# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Abhydrolase_5 PF12695.2 EPE24090.1 - 4.7e-05 23.1 0.2 7.3e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Epimerase PF01370.16 EPE24091.1 - 1.8e-12 47.1 0.1 5.8e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE24091.1 - 2e-09 37.7 0.0 3.3e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE24091.1 - 2.9e-06 26.1 0.0 8.2e-06 24.7 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EPE24091.1 - 6.3e-06 25.6 0.0 9.3e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EPE24091.1 - 0.00033 19.6 0.0 0.0046 15.9 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain TrkA_N PF02254.13 EPE24091.1 - 0.00034 20.5 0.1 0.00069 19.5 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.10 EPE24091.1 - 0.0051 16.6 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_4 PF07993.7 EPE24091.1 - 0.0082 15.0 0.3 0.024 13.5 0.1 1.7 1 1 1 2 2 2 1 Male sterility protein Pyr_redox PF00070.22 EPE24091.1 - 0.035 14.5 0.0 0.096 13.1 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EPE24091.1 - 0.073 13.5 0.1 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sugar_tr PF00083.19 EPE24092.1 - 1e-93 314.3 30.3 1.2e-93 314.2 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE24092.1 - 1.2e-27 96.5 25.2 1.2e-27 96.5 17.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE24092.1 - 0.00041 18.6 1.7 0.00041 18.6 1.2 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_31 PF01055.21 EPE24094.1 - 4.4e-113 378.4 0.2 5.3e-113 378.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EPE24094.1 - 3e-17 62.2 0.2 1.8e-16 59.6 0.0 2.6 3 0 0 3 3 3 1 Galactose mutarotase-like p450 PF00067.17 EPE24095.1 - 6.6e-54 183.1 0.0 9.2e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.13 EPE24096.1 - 5.7e-19 68.3 7.4 8.3e-19 67.8 5.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NUDIX PF00293.23 EPE24097.1 - 1e-11 44.6 0.1 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Iso_dh PF00180.15 EPE24098.1 - 6.1e-86 288.5 0.0 7.1e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1400 PF07176.6 EPE24098.1 - 0.087 12.7 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) PdxA PF04166.7 EPE24098.1 - 0.097 11.8 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthetic protein PdxA Catalase PF00199.14 EPE24099.1 - 8.9e-169 561.1 0.0 1.2e-168 560.7 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EPE24099.1 - 5.9e-11 42.0 0.0 1.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Bac_rhodopsin PF01036.13 EPE24101.1 - 3.3e-38 131.2 21.5 3.3e-38 131.2 14.9 1.7 2 0 0 2 2 2 1 Bacteriorhodopsin-like protein DUF809 PF05663.6 EPE24101.1 - 0.13 12.2 0.2 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF809) DUF3810 PF12725.2 EPE24101.1 - 9.5 5.0 8.0 1.1 8.1 2.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) GMC_oxred_N PF00732.14 EPE24102.1 - 4.7e-48 163.8 0.0 7.6e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE24102.1 - 5e-32 111.1 0.0 2.1e-31 109.1 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EPE24102.1 - 0.00095 18.1 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPE24102.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AAA PF00004.24 EPE24107.1 - 3.4e-18 66.1 0.0 7.9e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE24107.1 - 2.2e-05 25.2 0.3 0.00068 20.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EPE24107.1 - 0.00031 20.7 4.2 0.0027 17.6 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EPE24107.1 - 0.0016 18.1 0.0 0.0047 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EPE24107.1 - 0.0036 17.5 0.1 0.02 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE24107.1 - 0.0066 16.5 0.2 0.091 12.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EPE24107.1 - 0.2 11.4 0.2 0.54 10.0 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Pkinase PF00069.20 EPE24109.1 - 7.4e-25 87.5 0.0 1.2e-24 86.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE24109.1 - 2.4e-09 36.6 0.0 4.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPE24109.1 - 0.0002 21.1 0.1 0.0037 17.0 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPE24109.1 - 0.024 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF1098 PF06497.6 EPE24109.1 - 0.1 12.6 0.1 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) OPT PF03169.10 EPE24110.1 - 2.1e-209 697.0 33.9 2.5e-209 696.7 23.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GP46 PF07409.7 EPE24111.1 - 0.028 13.7 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 Phage protein GP46 3Beta_HSD PF01073.14 EPE24114.1 - 5.5e-40 136.8 0.0 6.5e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE24114.1 - 6.8e-26 91.1 0.0 9.1e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPE24114.1 - 7.5e-13 47.9 0.0 5.2e-10 38.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EPE24114.1 - 3.3e-05 22.9 0.0 4.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPE24114.1 - 5.2e-05 23.3 0.0 7.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPE24114.1 - 0.0014 18.6 0.1 0.0082 16.0 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Saccharop_dh PF03435.13 EPE24114.1 - 0.061 12.2 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 EPE24114.1 - 0.091 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family p450 PF00067.17 EPE24115.1 - 4.4e-34 117.7 0.0 5.9e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EPE24116.1 - 1.9e-36 125.5 45.4 1.5e-24 86.3 11.6 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE24116.1 - 3.9e-10 38.8 6.0 3.9e-10 38.8 4.2 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter DUF3186 PF11382.3 EPE24116.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Pam17 PF08566.5 EPE24116.1 - 0.69 9.5 3.0 2.5 7.7 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 zf-DHHC PF01529.15 EPE24119.1 - 0.047 13.0 1.4 0.061 12.7 0.4 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF2985 PF11204.3 EPE24119.1 - 4.6 7.0 13.6 0.79 9.5 4.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2985) Peptidase_M50B PF13398.1 EPE24120.1 - 9.9e-57 191.5 16.5 1.2e-56 191.2 11.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 EPE24120.1 - 0.0042 16.0 1.6 0.0082 15.1 0.1 2.2 1 1 1 2 2 2 1 Peptidase family M50 Peptidase_M41 PF01434.13 EPE24120.1 - 0.04 13.3 0.1 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M41 DUF373 PF04123.8 EPE24120.1 - 2.5 7.0 7.7 4.4 6.2 4.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) MLANA PF14991.1 EPE24120.1 - 4.9 7.1 5.9 3.5 7.6 0.2 2.3 1 1 1 2 2 2 0 Protein melan-A 7tm_2 PF00002.19 EPE24121.1 - 1.6e-11 43.8 6.5 2e-11 43.4 4.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.3 EPE24121.1 - 4.3e-11 42.7 9.3 6.3e-11 42.2 6.4 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 EPE24121.1 - 8.4e-09 34.7 7.1 8.4e-09 34.7 4.9 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 EPE24121.1 - 8e-08 31.7 3.3 1.1e-07 31.2 2.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEMspv1-c74-12 PF11044.3 EPE24121.1 - 0.057 12.9 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein TMEM190 PF15431.1 EPE24121.1 - 0.37 10.7 2.6 0.5 10.2 0.7 2.0 3 0 0 3 3 3 0 Transmembrane protein 190 HRXXH PF13933.1 EPE24122.1 - 0.0015 17.9 0.4 0.0022 17.4 0.3 1.2 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M35 PF02102.10 EPE24122.1 - 0.06 11.9 0.2 0.082 11.5 0.1 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family HRXXH PF13933.1 EPE24123.1 - 1.2e-06 28.1 0.2 1.9e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.1 EPE24123.1 - 0.003 18.0 0.0 0.01 16.3 0.0 1.9 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.10 EPE24123.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family MGDG_synth PF06925.6 EPE24125.1 - 0.029 14.2 0.1 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase Abhydrolase_6 PF12697.2 EPE24126.1 - 7.7e-16 58.6 0.0 2e-15 57.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE24126.1 - 0.028 14.1 0.1 0.064 13.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE24126.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold SPR1 PF15356.1 EPE24128.1 - 0.036 14.4 0.5 0.036 14.4 0.3 2.2 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 SKG6 PF08693.5 EPE24130.1 - 4.7e-06 25.8 0.2 4.7e-06 25.8 0.1 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Inositol_P PF00459.20 EPE24132.1 - 9.4e-62 208.7 0.0 1.1e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1134 PF06577.7 EPE24132.1 - 0.073 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) Alpha-amylase PF00128.19 EPE24133.1 - 9.4e-96 320.9 0.1 9.4e-96 320.9 0.0 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EPE24133.1 - 0.00083 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme zf-C2H2 PF00096.21 EPE24136.1 - 1.3 9.5 5.3 6.7 7.2 0.0 3.3 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE24136.1 - 4.3 7.8 6.9 8.8 6.9 0.0 3.0 4 0 0 4 4 4 0 C2H2-type zinc finger HET PF06985.6 EPE24137.1 - 4.9e-24 85.0 3.1 1.1e-23 83.9 2.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N_2 PF13602.1 EPE24138.1 - 2.6e-21 76.8 0.6 5.3e-21 75.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EPE24138.1 - 7.6e-17 61.0 0.1 1.4e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EPE24138.1 - 0.12 12.3 0.8 0.41 10.6 0.0 2.2 2 1 0 2 2 2 0 NADH(P)-binding DAGK_cat PF00781.19 EPE24139.1 - 2.5e-13 49.5 0.0 4.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain TT_ORF1 PF02956.9 EPE24142.1 - 2.4 6.4 6.8 4.3 5.6 4.7 1.3 1 0 0 1 1 1 0 TT viral orf 1 DUF604 PF04646.7 EPE24143.1 - 1.1e-06 28.1 0.3 5.3e-06 25.8 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EPE24143.1 - 0.029 13.5 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 Fringe-like HET PF06985.6 EPE24144.1 - 6.1e-18 65.3 0.6 1.2e-17 64.3 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pirin PF02678.11 EPE24145.1 - 2e-24 85.5 2.1 7.6e-24 83.6 1.5 1.9 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EPE24145.1 - 2.5e-05 23.7 1.0 0.006 16.0 0.3 3.2 2 1 0 2 2 2 2 Cupin domain His_Phos_2 PF00328.17 EPE24147.1 - 2.6e-122 408.5 0.5 3.4e-122 408.0 0.4 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EPE24147.1 - 5.5e-06 25.9 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 EPE24148.1 - 1e-83 280.1 0.0 1.4e-83 279.6 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EPE24148.1 - 2.5e-22 77.8 26.7 4.4e-06 26.3 0.9 8.8 9 0 0 9 9 9 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EPE24148.1 - 0.00022 20.1 0.0 1.3 7.7 0.0 3.5 4 0 0 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EPE24148.1 - 0.0015 16.9 0.0 0.0025 16.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain DUF4211 PF13926.1 EPE24149.1 - 7.6e-10 38.3 0.0 3e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4211) GPI2 PF06432.6 EPE24152.1 - 3.5e-117 390.7 1.1 4.3e-117 390.4 0.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3136 PF11334.3 EPE24152.1 - 0.08 12.3 0.3 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) YjgP_YjgQ PF03739.9 EPE24152.1 - 0.49 9.0 6.9 0.41 9.3 0.4 2.2 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family DUF4211 PF13926.1 EPE24154.1 - 8.2e-17 61.0 0.0 1.5e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Mhr1 PF12829.2 EPE24154.1 - 0.15 11.9 1.4 0.72 9.7 0.5 2.1 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination Raptor_N PF14538.1 EPE24157.1 - 0.023 14.5 0.3 0.093 12.5 0.0 2.2 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain adh_short PF00106.20 EPE24158.1 - 7e-16 58.5 0.7 6e-15 55.5 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE24158.1 - 1.1e-06 28.4 0.1 2.1e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE24158.1 - 0.0011 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPE24158.1 - 0.0028 17.1 0.0 0.0062 15.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.17 EPE24159.1 - 4.9e-51 173.6 0.0 6.2e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CHAT PF12770.2 EPE24160.1 - 8.5e-33 113.7 0.5 1.7e-32 112.6 0.1 1.7 2 0 0 2 2 2 1 CHAT domain TPR_12 PF13424.1 EPE24160.1 - 1.6e-07 31.1 4.3 0.086 12.7 0.0 7.1 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPE24160.1 - 3.8e-06 26.4 7.8 2.6 7.7 0.0 7.5 6 2 2 8 8 8 2 TPR repeat DUF4404 PF14357.1 EPE24160.1 - 0.0011 19.3 3.9 1.5 9.2 0.0 5.4 5 0 0 5 5 5 1 Domain of unknown function (DUF4404) DUF1041 PF06292.12 EPE24160.1 - 0.0091 16.1 0.0 3.2 7.9 0.0 3.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) TPR_1 PF00515.23 EPE24160.1 - 1.2 8.8 4.9 52 3.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPE24160.1 - 8.5 6.5 12.7 31 4.8 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat PAP_assoc PF03828.14 EPE24163.1 - 1.3e-16 60.2 0.0 1.1e-15 57.3 0.0 2.3 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPE24163.1 - 0.00023 21.4 0.0 0.0007 19.8 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain TFIIF_alpha PF05793.7 EPE24164.1 - 2e-07 29.7 64.7 4e-07 28.8 37.0 4.5 1 1 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.4 EPE24165.1 - 1.4e-31 109.7 12.7 1.4e-31 109.7 8.8 2.0 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex HTH_Tnp_Mu_1 PF02316.11 EPE24165.1 - 0.085 12.5 2.5 0.22 11.2 1.7 1.8 1 0 0 1 1 1 0 Mu DNA-binding domain zf-C2H2_4 PF13894.1 EPE24166.1 - 0.89 10.0 5.5 0.49 10.8 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger ABC2_membrane_4 PF12730.2 EPE24167.1 - 0.045 12.9 8.1 0.065 12.3 5.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1469 PF07332.6 EPE24167.1 - 0.82 9.4 7.0 1.7 8.3 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Aldo_ket_red PF00248.16 EPE24169.1 - 3.7e-63 213.0 0.0 4.2e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zip PF02535.17 EPE24170.1 - 0.12 11.3 6.6 0.15 11.0 0.4 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter PrsW-protease PF13367.1 EPE24171.1 - 0.14 11.3 0.8 0.2 10.8 0.5 1.2 1 0 0 1 1 1 0 Protease prsW family SPRY PF00622.23 EPE24172.1 - 2.1e-10 40.7 0.0 9.6e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 SPRY domain YjgP_YjgQ PF03739.9 EPE24173.1 - 0.0006 18.6 0.0 0.00075 18.3 0.0 1.2 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family Tweety PF04906.8 EPE24173.1 - 0.0029 16.1 1.6 0.0039 15.6 1.1 1.2 1 0 0 1 1 1 1 Tweety DUF2207 PF09972.4 EPE24173.1 - 0.12 10.9 0.5 0.16 10.5 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1700 PF08006.6 EPE24173.1 - 6.7 5.9 11.2 2.8 7.2 6.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) zf-RING_2 PF13639.1 EPE24175.1 - 1.6e-13 50.1 5.7 2.6e-13 49.5 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EPE24175.1 - 1.7e-12 46.9 0.0 5.3e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EPE24175.1 - 5.4e-09 35.9 5.3 8.5e-09 35.2 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE24175.1 - 1.1e-08 34.5 2.7 1.8e-08 33.9 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE24175.1 - 1.2e-08 34.9 3.9 2.2e-08 34.0 2.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EPE24175.1 - 1e-07 31.4 3.1 1.5e-07 30.9 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE24175.1 - 3.8e-07 29.7 2.2 5.9e-07 29.1 1.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPE24175.1 - 0.0012 18.6 0.9 0.0022 17.7 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EPE24175.1 - 0.046 13.6 3.4 0.14 12.0 2.4 1.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EPE24175.1 - 0.12 12.3 1.9 0.28 11.1 1.3 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EPE24175.1 - 0.13 12.2 3.3 0.25 11.3 2.3 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EPE24175.1 - 0.14 11.9 2.6 0.29 10.8 1.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 EPE24175.1 - 0.23 11.4 3.5 0.42 10.6 2.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EPE24175.1 - 0.36 10.4 2.4 0.66 9.5 1.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EPE24175.1 - 1.1 8.9 2.6 2.1 8.1 1.8 1.5 1 0 0 1 1 1 0 PHD-finger MIP PF00230.15 EPE24176.1 - 7.5e-50 169.5 16.4 9.8e-50 169.1 11.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Abhydrolase_5 PF12695.2 EPE24177.1 - 1.7e-06 27.8 0.0 2.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EPE24177.1 - 1.9e-05 23.3 0.0 0.0024 16.4 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EPE24177.1 - 0.00088 18.5 0.0 0.0073 15.5 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 EPE24177.1 - 0.0059 15.8 0.0 0.012 14.8 0.0 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 EPE24177.1 - 0.028 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EPE24177.1 - 0.07 12.5 0.0 1.5 8.2 0.0 2.2 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase VCBS PF13517.1 EPE24178.1 - 5.4e-27 93.9 27.3 1.5e-11 44.5 0.5 7.4 3 3 5 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EPE24178.1 - 1.8e-14 52.9 26.2 0.0049 16.5 0.0 7.1 6 0 0 6 6 6 5 FG-GAP repeat Lipase_GDSL PF00657.17 EPE24178.1 - 4.6e-14 52.8 0.3 1e-13 51.6 0.2 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EPE24178.1 - 4.8e-13 49.6 0.0 1.5e-12 47.9 0.0 2.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 EPE24178.1 - 0.00052 19.5 10.5 0.42 10.0 0.1 6.5 3 2 3 7 7 7 2 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 EPE24178.1 - 0.00069 19.3 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SprT-like PF10263.4 EPE24179.1 - 0.0001 21.9 0.4 0.00019 21.0 0.3 1.6 1 1 0 1 1 1 1 SprT-like family Zn_clus PF00172.13 EPE24180.1 - 2.6e-07 30.4 14.0 4.3e-07 29.7 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF937 PF06078.6 EPE24181.1 - 1.7 8.9 7.9 1.3 9.2 0.7 2.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Anoctamin PF04547.7 EPE24183.1 - 4.2e-118 394.8 1.6 5.3e-118 394.5 1.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Metallophos PF00149.23 EPE24184.1 - 3.8e-09 36.2 0.6 1.2e-08 34.6 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPE24184.1 - 5.1e-07 29.6 0.0 5.3e-06 26.3 0.0 2.2 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EPE24184.1 - 0.093 11.8 0.0 0.27 10.3 0.0 1.7 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily MutL PF13941.1 EPE24184.1 - 0.1 10.9 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 MutL protein DUF946 PF06101.6 EPE24185.1 - 2.2e-12 45.7 0.8 6.1e-11 41.0 0.4 2.1 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) NPP1 PF05630.6 EPE24185.1 - 0.066 12.9 1.8 0.12 12.0 1.3 1.4 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Myb_DNA-binding PF00249.26 EPE24186.1 - 0.0015 18.5 0.1 0.0043 17.0 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0016 PF01169.14 EPE24187.1 - 9.8e-42 140.9 22.8 7.8e-21 74.0 5.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF1996 PF09362.5 EPE24188.1 - 1.7e-88 296.2 0.5 2.4e-88 295.7 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RNA_pol_3_Rpc31 PF11705.3 EPE24190.1 - 1.1e-44 153.1 12.1 1.2e-44 153.0 8.4 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.4 EPE24190.1 - 5.1 5.6 15.8 7.1 5.2 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Bac_rhodopsin PF01036.13 EPE24192.1 - 7.8e-59 198.6 19.8 9.8e-59 198.3 13.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MARVEL PF01284.18 EPE24192.1 - 1.8 8.4 14.1 4.4 7.1 2.5 2.3 2 0 0 2 2 2 0 Membrane-associating domain RPE65 PF03055.10 EPE24193.1 - 3.2e-133 444.8 0.0 3.7e-133 444.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PPI_Ypi1 PF07491.6 EPE24193.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor SQS_PSY PF00494.14 EPE24194.1 - 2.1e-66 223.9 0.1 2.7e-66 223.6 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Peptidase_C48 PF02902.14 EPE24195.1 - 1.9e-09 37.4 0.1 2.3e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain NAD_binding_8 PF13450.1 EPE24196.1 - 3.3e-15 55.8 0.1 8.5e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE24196.1 - 3.5e-15 55.7 2.7 7.3e-14 51.4 1.3 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EPE24196.1 - 1.5e-14 53.9 0.0 1.2e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EPE24196.1 - 1e-09 37.8 1.2 2e-06 26.9 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EPE24196.1 - 6.2e-08 31.5 1.1 0.0024 16.4 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EPE24196.1 - 4.4e-07 29.9 0.0 6e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE24196.1 - 1.1e-06 28.8 0.0 0.0022 18.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPE24196.1 - 4.9e-06 25.8 0.0 0.00072 18.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.13 EPE24196.1 - 0.00023 19.6 0.1 0.067 11.4 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Strep_67kDa_ant PF06100.6 EPE24196.1 - 0.0015 16.9 0.0 0.61 8.3 0.0 2.1 2 0 0 2 2 2 2 Streptococcal 67 kDa myosin-cross-reactive antigen like family Pyr_redox PF00070.22 EPE24196.1 - 0.0017 18.7 2.9 0.14 12.5 0.8 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE24196.1 - 0.0026 16.8 0.6 0.0026 16.8 0.4 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EPE24196.1 - 0.0037 16.3 1.2 0.0062 15.6 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Spore_YabQ PF09578.5 EPE24196.1 - 0.0087 15.9 0.6 0.021 14.7 0.4 1.6 1 0 0 1 1 1 1 Spore cortex protein YabQ (Spore_YabQ) GIDA PF01134.17 EPE24196.1 - 0.016 14.0 6.0 0.024 13.4 1.4 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GMC_oxred_N PF00732.14 EPE24196.1 - 0.034 13.2 0.7 1.4 8.0 0.1 2.3 2 0 0 2 2 2 0 GMC oxidoreductase 3HCDH_N PF02737.13 EPE24196.1 - 0.044 13.4 0.8 0.082 12.5 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EPE24196.1 - 0.1 11.1 4.3 1.8 7.0 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EPE24196.1 - 0.13 12.0 4.1 0.18 11.5 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EPE24196.1 - 1.4 7.7 4.3 0.43 9.4 0.3 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein DEAD PF00270.24 EPE24197.1 - 3.7e-42 143.6 0.0 1.7e-41 141.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE24197.1 - 6.1e-23 80.4 0.4 2.4e-22 78.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPE24197.1 - 5.4e-08 31.9 0.0 1.8e-07 30.2 0.0 1.9 2 1 1 3 3 3 1 SNF2 family N-terminal domain Septin PF00735.13 EPE24199.1 - 1.6e-30 106.0 0.0 2.2e-10 40.0 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 EPE24199.1 - 0.0009 18.7 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.15 EPE24199.1 - 0.016 13.9 0.0 0.029 13.0 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit Miro PF08477.8 EPE24199.1 - 0.03 14.8 0.0 0.089 13.2 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 EPE24199.1 - 0.039 13.7 1.3 0.081 12.7 0.2 2.0 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.1 EPE24199.1 - 0.12 12.3 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EPE24199.1 - 0.14 12.1 0.8 0.99 9.3 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain HET PF06985.6 EPE24200.1 - 1.2e-19 70.8 10.4 3.7e-18 66.0 0.7 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 EPE24201.1 - 3.8e-35 121.0 1.2 8.4e-35 119.9 0.8 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC1 PF03109.11 EPE24202.1 - 8.8e-24 83.7 0.0 2.1e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EPE24202.1 - 0.055 13.2 0.1 0.15 11.7 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family SUR7 PF06687.7 EPE24203.1 - 4e-27 95.1 13.8 5.1e-27 94.8 9.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4231 PF14015.1 EPE24203.1 - 0.0037 17.2 0.3 0.0094 15.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) NfeD PF01957.13 EPE24203.1 - 0.028 14.5 0.8 0.028 14.5 0.6 2.1 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding CobD_Cbib PF03186.8 EPE24203.1 - 0.19 10.7 2.1 0.3 10.1 1.5 1.2 1 0 0 1 1 1 0 CobD/Cbib protein DUF3507 PF12015.3 EPE24204.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) DUF1768 PF08719.6 EPE24205.1 - 6.3e-50 168.9 0.0 7.4e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Talin_middle PF09141.5 EPE24206.1 - 0.0059 16.3 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Talin, middle domain Acyl_transf_3 PF01757.17 EPE24207.1 - 2e-24 86.0 32.6 9.9e-24 83.7 22.6 1.8 1 1 0 1 1 1 1 Acyltransferase family Isochorismatase PF00857.15 EPE24208.1 - 1.8e-38 132.2 0.0 2.1e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Fungal_trans_2 PF11951.3 EPE24209.1 - 1.2e-11 43.9 0.0 1.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RCR PF12273.3 EPE24210.1 - 2.2e-13 50.9 7.3 3e-13 50.4 5.1 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red tRNA-synt_2c PF01411.14 EPE24212.1 - 6.4e-214 711.3 0.1 6.4e-214 711.3 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EPE24212.1 - 8.5e-17 60.7 0.5 2e-16 59.5 0.3 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain FKBP_N PF01346.13 EPE24212.1 - 0.0029 17.6 5.4 0.0029 17.6 3.7 2.4 4 0 0 4 4 4 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DHHA1 PF02272.14 EPE24212.1 - 0.068 12.8 0.1 0.18 11.5 0.1 1.8 1 0 0 1 1 1 0 DHHA1 domain XPC-binding PF09280.6 EPE24212.1 - 0.18 11.2 0.1 0.64 9.5 0.0 1.9 2 0 0 2 2 2 0 XPC-binding domain AATase PF07247.7 EPE24213.1 - 1.9e-33 115.7 0.0 2.5e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EPE24213.1 - 1.8e-09 36.9 0.0 8.6e-09 34.6 0.0 1.8 1 1 0 1 1 1 1 Condensation domain Bul1_N PF04425.7 EPE24215.1 - 1.8e-10 39.9 1.7 0.00013 20.7 0.1 3.2 2 1 1 3 3 3 3 Bul1 N terminus Arrestin_N PF00339.24 EPE24215.1 - 8.6e-06 25.6 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EPE24215.1 - 0.047 12.8 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Bul1 C terminus MBOAT PF03062.14 EPE24217.1 - 1.5e-42 145.8 18.9 1.5e-42 145.8 13.1 2.6 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family ESSS PF10183.4 EPE24217.1 - 0.035 14.5 0.0 0.087 13.2 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) adh_short PF00106.20 EPE24219.1 - 2.2e-13 50.4 0.0 3.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE24219.1 - 4.4e-05 23.2 0.0 6.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE24219.1 - 0.0013 18.5 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPE24219.1 - 0.021 14.8 0.1 0.043 13.8 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EPE24219.1 - 0.13 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peptidase_S41 PF03572.13 EPE24220.1 - 2e-06 27.3 0.0 5.9e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 Ank_2 PF12796.2 EPE24221.1 - 7.7e-73 240.8 10.6 1.6e-14 53.9 0.2 8.0 4 1 5 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE24221.1 - 3.6e-48 161.1 7.1 9.7e-07 29.1 0.0 10.1 7 2 4 11 11 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE24221.1 - 1.7e-43 145.6 8.6 4.7e-06 26.6 0.0 9.7 5 2 6 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.25 EPE24221.1 - 1.3e-42 141.4 16.2 8.6e-07 28.4 0.1 11.6 13 0 0 13 13 12 7 Ankyrin repeat Ank_3 PF13606.1 EPE24221.1 - 1.2e-34 114.8 16.1 0.00047 20.1 0.0 12.8 13 0 0 13 13 13 7 Ankyrin repeat AAA_16 PF13191.1 EPE24221.1 - 0.0022 17.9 0.1 0.01 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EPE24221.1 - 0.0084 16.4 5.7 0.25 11.6 0.0 4.2 2 1 0 2 2 2 1 AAA domain Clathrin PF00637.15 EPE24221.1 - 0.0086 15.6 3.5 0.024 14.2 1.5 2.5 3 0 0 3 3 3 1 Region in Clathrin and VPS AAA_22 PF13401.1 EPE24221.1 - 0.048 13.8 0.0 0.5 10.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF1664 PF07889.7 EPE24221.1 - 0.78 9.5 9.0 0.11 12.2 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3647 PF12363.3 EPE24221.1 - 3 7.9 9.7 0.22 11.6 0.2 3.9 4 1 1 5 5 5 0 Phage protein MFS_1_like PF12832.2 EPE24222.1 - 1.8e-06 27.6 6.2 4.1e-05 23.2 0.1 3.5 3 0 0 3 3 3 2 MFS_1 like family DUF2306 PF10067.4 EPE24223.1 - 1.6e-09 37.8 7.3 1.6e-09 37.8 5.0 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) PepSY_TM_3 PF13706.1 EPE24223.1 - 2.8 7.4 7.8 6.7 6.2 1.0 3.0 2 0 0 2 2 2 0 PepSY-associated TM helix DUF1793 PF08760.6 EPE24224.1 - 1.3e-60 204.1 0.0 3.2e-60 202.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4518 PF15008.1 EPE24224.1 - 0.028 13.4 0.1 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Bap31 PF05529.7 EPE24225.1 - 6.7e-68 227.9 2.6 7.5e-68 227.7 1.8 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DivIC PF04977.10 EPE24225.1 - 0.00026 20.4 1.2 0.0099 15.3 0.1 2.7 2 0 0 2 2 2 1 Septum formation initiator Mod_r PF07200.8 EPE24225.1 - 0.031 14.1 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CCDC155 PF14662.1 EPE24225.1 - 0.037 13.6 0.6 0.055 13.0 0.4 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 TMF_DNA_bd PF12329.3 EPE24225.1 - 0.038 13.7 2.3 0.065 13.0 1.6 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2956 PF11169.3 EPE24225.1 - 0.5 10.3 3.4 0.96 9.4 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Dus PF01207.12 EPE24226.1 - 1.1e-39 136.1 0.0 9.2e-29 100.2 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EPE24226.1 - 0.019 14.6 2.4 2.6 7.8 0.1 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_3 PF13415.1 EPE24227.1 - 2.1e-43 145.5 7.1 9.1e-08 32.0 0.0 6.8 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EPE24227.1 - 2.3e-40 136.1 14.1 6.9e-09 35.3 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EPE24227.1 - 5.8e-38 128.2 12.1 3e-06 27.0 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EPE24227.1 - 7.7e-38 127.7 10.4 1.7e-06 27.4 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EPE24227.1 - 3.1e-34 115.7 10.0 1.4e-06 28.2 0.0 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EPE24227.1 - 4.2e-29 99.1 15.2 1.8e-05 24.3 0.0 6.5 6 1 0 6 6 6 6 Kelch motif HIG_1_N PF04588.8 EPE24228.1 - 2e-08 33.8 2.5 3.5e-08 33.0 1.7 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Macoilin PF09726.4 EPE24228.1 - 0.063 11.5 17.4 0.074 11.3 12.0 1.2 1 0 0 1 1 1 0 Transmembrane protein zf-C2H2_4 PF13894.1 EPE24229.1 - 1.5e-05 25.0 8.2 0.039 14.2 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE24229.1 - 5.9e-05 23.1 7.6 0.0042 17.3 0.5 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPE24229.1 - 0.0017 18.5 13.2 0.056 13.8 1.0 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EPE24229.1 - 0.0077 16.3 5.6 0.04 14.0 0.2 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding SprT-like PF10263.4 EPE24229.1 - 0.094 12.3 0.8 0.16 11.6 0.6 1.4 1 0 0 1 1 1 0 SprT-like family zf-C2H2_6 PF13912.1 EPE24229.1 - 1.4 8.9 7.3 0.11 12.4 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger HET PF06985.6 EPE24230.1 - 3.6e-34 117.8 0.8 6.6e-34 117.0 0.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3425 PF11905.3 EPE24231.1 - 5.7e-20 71.5 0.1 1e-19 70.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EPE24231.1 - 0.0005 19.9 4.8 0.00099 19.0 3.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPE24231.1 - 0.048 13.4 5.7 0.091 12.5 4.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DUF4345 PF14248.1 EPE24232.1 - 0.016 14.6 6.5 0.56 9.6 1.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4345) 7tm_1 PF00001.16 EPE24232.1 - 0.026 13.6 0.2 0.035 13.2 0.2 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) MNHE PF01899.11 EPE24232.1 - 0.054 13.1 0.6 0.088 12.4 0.4 1.4 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit DUF385 PF04075.9 EPE24232.1 - 0.075 12.9 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF385) Scm3 PF10384.4 EPE24233.1 - 2.1e-20 71.9 0.2 4.8e-20 70.7 0.1 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_2 PF08914.6 EPE24233.1 - 0.036 13.8 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Rap1 Myb domain APG6 PF04111.7 EPE24234.1 - 6.3e-128 426.2 0.3 7.8e-128 425.9 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 EPE24234.1 - 0.13 10.1 3.1 0.17 9.6 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.4 EPE24234.1 - 0.24 11.3 6.7 0.44 10.5 4.6 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4337 PF14235.1 EPE24234.1 - 4 7.2 6.8 7.9 6.2 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Pkinase PF00069.20 EPE24235.1 - 5e-36 124.1 0.6 1.5e-23 83.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE24235.1 - 6.5e-07 28.6 0.4 9.6e-05 21.5 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase CPSase_sm_chain PF00988.17 EPE24237.1 - 1.2e-47 160.6 0.0 2.4e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EPE24237.1 - 2e-44 151.3 0.1 2.7e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPE24237.1 - 3.3e-06 26.7 0.1 0.00055 19.4 0.1 2.8 2 1 0 2 2 2 1 Peptidase C26 ETF PF01012.16 EPE24238.1 - 4.5e-35 120.7 0.0 6.5e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AAA_17 PF13207.1 EPE24239.1 - 0.0033 18.2 0.0 0.012 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EPE24239.1 - 0.064 12.8 0.1 0.6 9.6 0.0 2.5 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EPE24239.1 - 0.072 13.3 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Bac_luciferase PF00296.15 EPE24240.1 - 2e-62 211.1 0.0 2.6e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_zinc_N PF00107.21 EPE24241.1 - 4.2e-07 29.5 0.3 8e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE24241.1 - 0.0014 18.3 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Grp1_Fun34_YaaH PF01184.14 EPE24242.1 - 1e-36 126.2 23.8 1.2e-36 125.9 16.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Acyl-CoA_dh_2 PF08028.6 EPE24243.1 - 2.1e-18 66.8 0.5 4e-18 65.9 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EPE24243.1 - 1.1e-08 35.5 0.2 6e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EPE24243.1 - 1.8e-05 24.8 0.2 3.8e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MH2 PF03166.9 EPE24244.1 - 0.081 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 MH2 domain DUF904 PF06005.7 EPE24245.1 - 0.0049 17.1 7.8 0.17 12.1 0.4 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF904) Leu_zip PF15294.1 EPE24245.1 - 0.036 13.1 2.5 0.52 9.3 0.1 2.2 2 0 0 2 2 2 0 Leucine zipper SlyX PF04102.7 EPE24245.1 - 0.04 14.2 4.9 4.4 7.7 0.2 3.0 3 0 0 3 3 3 0 SlyX DivIC PF04977.10 EPE24245.1 - 0.094 12.2 7.8 2.8 7.5 2.1 2.6 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 EPE24245.1 - 0.25 11.3 10.0 0.2 11.6 0.3 3.0 3 0 0 3 3 2 0 bZIP transcription factor DUF972 PF06156.8 EPE24245.1 - 0.25 11.6 2.7 17 5.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DASH_Spc19 PF08287.6 EPE24245.1 - 0.26 10.9 8.8 0.89 9.1 0.1 3.2 3 0 0 3 3 3 0 Spc19 TMF_DNA_bd PF12329.3 EPE24245.1 - 1.2 8.9 6.7 13 5.7 0.2 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Rootletin PF15035.1 EPE24245.1 - 1.4 8.8 8.7 0.56 10.1 0.6 2.8 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Prefoldin_2 PF01920.15 EPE24245.1 - 2.3 8.0 5.2 21 4.9 0.5 2.5 2 0 0 2 2 2 0 Prefoldin subunit Tropomyosin_1 PF12718.2 EPE24245.1 - 4.6 7.0 10.1 4.8 7.0 3.8 2.6 2 1 1 3 3 3 0 Tropomyosin like TRI12 PF06609.8 EPE24246.1 - 3.7e-75 253.3 21.8 4.8e-75 252.9 15.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EPE24246.1 - 7.7e-26 90.6 43.4 7.7e-26 90.6 30.0 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE24246.1 - 8.5e-09 34.4 8.4 8.5e-09 34.4 5.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter adh_short PF00106.20 EPE24247.1 - 1.2e-26 93.5 0.7 2.6e-26 92.5 0.6 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE24247.1 - 9.2e-23 81.2 0.4 1.1e-22 80.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE24247.1 - 1.2e-13 51.1 0.2 2.2e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPE24247.1 - 0.37 10.5 4.0 0.78 9.5 0.1 2.8 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zn_clus PF00172.13 EPE24248.1 - 5.7e-09 35.7 7.8 5.7e-09 35.7 5.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.23 EPE24249.1 - 1.8e-81 274.5 0.1 3.4e-81 273.5 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE24249.1 - 1.4e-10 41.1 0.3 5.2e-10 39.2 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE24249.1 - 0.0033 16.6 0.9 0.0068 15.6 0.3 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE24249.1 - 0.08 12.7 0.2 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 EPE24250.1 - 1.4e-37 129.2 53.3 3e-36 124.8 35.8 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPE24250.1 - 8.8e-23 80.3 24.5 1.2e-22 79.9 17.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE24250.1 - 8.1e-12 44.4 7.5 8.1e-12 44.4 5.2 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter ABC_tran PF00005.22 EPE24251.1 - 3e-45 153.9 5.2 1.7e-23 83.4 0.1 3.6 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EPE24251.1 - 3.2e-19 69.9 6.9 3.3e-06 27.2 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EPE24251.1 - 9.1e-11 41.4 0.4 0.0053 16.0 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EPE24251.1 - 1.1e-08 35.8 0.2 0.003 18.3 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EPE24251.1 - 3.5e-08 32.8 2.8 0.00069 19.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EPE24251.1 - 5e-07 29.9 4.1 0.01 15.9 0.1 4.2 2 2 1 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EPE24251.1 - 3.6e-06 26.9 1.0 0.011 15.6 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EPE24251.1 - 2.3e-05 24.8 0.2 0.22 12.0 0.0 3.0 2 1 0 2 2 2 2 Miro-like protein ABC_tran_2 PF12848.2 EPE24251.1 - 3.5e-05 23.5 6.2 3.5e-05 23.5 4.3 1.9 2 0 0 2 2 1 1 ABC transporter AAA PF00004.24 EPE24251.1 - 0.00011 22.3 0.2 0.021 15.0 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EPE24251.1 - 0.00022 21.1 4.4 0.14 12.0 0.0 3.4 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 EPE24251.1 - 0.00023 20.4 0.1 0.59 9.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 EPE24251.1 - 0.00024 21.1 2.5 0.35 10.8 0.2 3.5 2 1 1 3 3 3 2 AAA domain MobB PF03205.9 EPE24251.1 - 0.00053 19.7 1.1 0.66 9.6 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EPE24251.1 - 0.00058 19.4 4.4 0.51 9.8 1.4 3.2 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.8 EPE24251.1 - 0.00066 18.6 0.1 0.26 10.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EPE24251.1 - 0.00073 19.5 15.3 0.2 11.6 0.5 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 EPE24251.1 - 0.002 18.4 6.3 0.84 9.9 0.8 3.4 3 1 0 3 3 2 2 AAA domain ArgK PF03308.11 EPE24251.1 - 0.004 15.9 1.2 0.12 11.1 0.1 2.5 2 0 0 2 2 2 1 ArgK protein NTPase_1 PF03266.10 EPE24251.1 - 0.0051 16.5 0.6 3 7.5 0.0 3.5 4 0 0 4 4 3 1 NTPase AAA_5 PF07728.9 EPE24251.1 - 0.0056 16.4 0.4 3.3 7.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 EPE24251.1 - 0.0067 16.2 5.8 0.72 9.6 0.4 3.1 3 1 0 3 3 2 2 Dynamin family RNA_helicase PF00910.17 EPE24251.1 - 0.0075 16.4 0.1 2.1 8.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 EPE24251.1 - 0.0079 16.0 0.2 11 5.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EPE24251.1 - 0.0081 15.8 0.6 2.2 7.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.1 EPE24251.1 - 0.014 14.5 9.9 0.031 13.3 0.0 3.4 4 1 0 5 5 4 0 AAA ATPase domain AAA_25 PF13481.1 EPE24251.1 - 0.09 12.1 4.7 0.38 10.1 0.4 2.8 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EPE24251.1 - 0.097 11.1 15.4 1 7.7 0.0 4.0 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 EPE24251.1 - 0.1 12.0 3.5 0.59 9.5 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EPE24251.1 - 0.22 11.8 23.7 1.1 9.6 5.4 4.0 3 1 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EPE24251.1 - 0.71 9.2 6.7 3.6 6.9 0.3 3.1 2 1 0 2 2 2 0 AAA-like domain Thymidylate_kin PF02223.12 EPE24251.1 - 2.7 7.3 9.7 1.7 8.0 0.0 3.5 4 0 0 4 4 4 0 Thymidylate kinase AAA_19 PF13245.1 EPE24251.1 - 3.1 7.6 7.8 0.5 10.1 0.2 2.9 3 0 0 3 3 2 0 Part of AAA domain Arf PF00025.16 EPE24251.1 - 3.3 6.8 7.0 3.5 6.8 0.3 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family Pyr_redox_3 PF13738.1 EPE24253.1 - 4.9e-20 72.4 0.0 1e-19 71.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE24253.1 - 8.6e-13 47.3 0.0 4.7e-10 38.2 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EPE24253.1 - 5.5e-11 42.3 0.0 1.8e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPE24253.1 - 1.4e-05 24.9 0.0 6.7e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPE24253.1 - 1.9e-05 23.7 0.1 0.038 12.9 0.0 3.4 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EPE24253.1 - 0.021 13.9 0.0 0.052 12.6 0.0 1.6 2 0 0 2 2 2 0 Thi4 family adh_short PF00106.20 EPE24254.1 - 1.5e-23 83.5 0.1 2e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE24254.1 - 1.8e-16 60.6 0.1 2.7e-16 60.0 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE24254.1 - 4.7e-10 39.4 0.0 6.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EPE24254.1 - 0.0011 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.16 EPE24254.1 - 0.01 15.3 0.1 0.016 14.6 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPE24254.1 - 0.025 13.4 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EPE24254.1 - 0.08 12.7 0.9 0.19 11.5 0.6 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.16 EPE24254.1 - 0.12 12.2 0.2 0.6 9.9 0.0 2.1 1 1 2 3 3 3 0 ThiF family HHH_5 PF14520.1 EPE24254.1 - 0.13 12.4 0.2 0.28 11.3 0.1 1.6 1 1 0 1 1 1 0 Helix-hairpin-helix domain C5-epim_C PF06662.8 EPE24255.1 - 0.095 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Fungal_trans PF04082.13 EPE24256.1 - 5.8e-17 61.4 0.1 2.7e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE24256.1 - 1e-07 31.7 9.2 2.7e-07 30.3 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1446 PF07287.6 EPE24257.1 - 1.7e-121 405.1 0.1 2e-121 404.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Abhydrolase_3 PF07859.8 EPE24258.1 - 3.7e-58 196.5 0.1 4.8e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EPE24258.1 - 2.1e-07 30.0 0.0 4.5e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 EPE24258.1 - 5.8e-06 25.1 0.0 7.9e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPE24258.1 - 7.8e-05 22.4 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE24258.1 - 0.0002 21.3 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EPE24258.1 - 0.028 14.6 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.3 EPE24258.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Acyl-CoA_dh_1 PF00441.19 EPE24259.1 - 9.2e-26 90.7 0.1 1.4e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EPE24259.1 - 1.1e-11 45.3 0.6 2.8e-11 43.9 0.0 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EPE24259.1 - 3e-10 40.4 0.0 5.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPE24259.1 - 7.5e-09 34.9 0.0 1.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Glyco_hydro_114 PF03537.8 EPE24260.1 - 9.8e-23 79.7 0.1 1.7e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 DUF4286 PF14114.1 EPE24262.1 - 0.0079 16.4 0.1 0.092 13.0 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4286) EthD PF07110.6 EPE24262.1 - 0.05 14.5 2.4 0.057 14.3 0.0 2.2 3 0 0 3 3 3 0 EthD domain Aldedh PF00171.17 EPE24263.1 - 6e-154 512.7 0.0 6.8e-154 512.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPE24263.1 - 0.015 14.0 0.0 0.052 12.2 0.0 1.7 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) PAT1 PF09770.4 EPE24264.1 - 3.1 5.9 14.0 4 5.5 9.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rick_17kDa_Anti PF05433.10 EPE24264.1 - 9.8 5.9 13.8 1.3e+02 2.3 9.7 2.1 1 1 0 1 1 1 0 Glycine zipper 2TM domain Fungal_trans PF04082.13 EPE24266.1 - 8.6e-27 93.6 0.0 2.8e-26 91.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE24266.1 - 0.00024 20.9 11.4 0.0005 19.9 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 EPE24267.1 - 1.8e-18 67.3 0.0 9e-18 65.0 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE24267.1 - 8e-14 50.7 0.1 2.4e-12 45.8 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EPE24267.1 - 8e-12 45.0 0.0 2.3e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EPE24267.1 - 1e-07 31.2 0.0 0.00037 19.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPE24267.1 - 3.9e-05 23.4 0.1 0.00023 20.9 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EPE24267.1 - 0.053 12.4 0.0 0.45 9.3 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase AMP-binding PF00501.23 EPE24268.1 - 5.3e-85 285.3 0.0 7.4e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE24268.1 - 1.7e-09 38.4 1.8 2.1e-09 38.1 0.3 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 EPE24269.1 - 5.3e-28 98.0 2.5 6.7e-28 97.6 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE24269.1 - 1.8e-27 96.6 0.0 2.6e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE24269.1 - 2.3e-13 50.2 0.7 4.5e-13 49.2 0.5 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPE24269.1 - 0.069 12.9 0.6 0.19 11.5 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EPE24269.1 - 0.11 11.8 0.2 0.31 10.4 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 EPE24270.1 - 7.1e-78 262.1 0.0 9.4e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sigma70_r2 PF04542.9 EPE24270.1 - 0.013 15.0 0.4 0.097 12.2 0.1 2.4 2 0 0 2 2 2 0 Sigma-70 region 2 DUF1924 PF09086.6 EPE24270.1 - 0.085 12.9 0.1 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) CorA PF01544.13 EPE24271.1 - 0.00018 20.6 0.7 0.00038 19.5 0.5 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sec6 PF06046.8 EPE24271.1 - 0.00029 19.0 0.0 0.00056 18.1 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec6 RdRP PF05183.7 EPE24272.1 - 7.7e-178 592.7 0.0 1e-177 592.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase MORN PF02493.15 EPE24272.1 - 0.18 11.5 0.2 17 5.3 0.0 2.7 2 0 0 2 2 2 0 MORN repeat Vasohibin PF14822.1 EPE24273.1 - 0.021 13.8 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Vasohibin Phage_int_SAM_4 PF13495.1 EPE24273.1 - 0.032 14.5 0.1 0.061 13.6 0.1 1.7 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Fumble PF03630.9 EPE24274.1 - 3.3e-130 433.9 0.0 2.7e-129 430.9 0.0 1.9 1 1 0 1 1 1 1 Fumble Sushi_2 PF09014.5 EPE24275.1 - 0.061 13.1 0.2 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Calsarcin PF05556.6 EPE24278.1 - 0.032 13.4 0.2 0.053 12.7 0.1 1.3 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) 2OG-FeII_Oxy_3 PF13640.1 EPE24279.1 - 4.2e-13 49.6 0.0 6.6e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EPE24279.1 - 6.1e-07 28.9 0.0 1.8e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPE24279.1 - 8.6e-06 25.9 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 EPE24280.1 - 5.6e-18 65.4 0.0 1.1e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE24280.1 - 8.1e-14 51.9 0.0 1.9e-06 27.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE24280.1 - 2.1e-08 34.0 0.0 3.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 KR domain MoaE PF02391.12 EPE24281.1 - 4.1e-33 113.6 0.0 5.7e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 MoaE protein RRM_1 PF00076.17 EPE24283.1 - 1.7e-12 46.7 0.4 7.7e-05 22.2 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE24283.1 - 2.1e-11 43.6 0.0 4.4e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 EPE24283.1 - 2.6e-09 36.7 1.8 2.6e-09 36.7 1.2 2.2 2 0 0 2 2 2 1 G-patch domain zf-RanBP PF00641.13 EPE24283.1 - 7.2e-08 31.3 1.8 1.5e-07 30.4 1.2 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.2 EPE24283.1 - 1.9e-07 30.7 0.2 7e-07 29.0 0.2 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_5 PF13893.1 EPE24283.1 - 1e-05 25.2 0.0 0.067 13.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 EPE24283.1 - 0.00032 20.7 3.6 0.0009 19.3 2.5 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RED_N PF07808.8 EPE24283.1 - 0.0053 16.0 0.6 0.0053 16.0 0.4 2.6 4 0 0 4 4 4 1 RED-like protein N-terminal region zf-C2H2_2 PF12756.2 EPE24283.1 - 0.041 13.9 0.4 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Glyco_hydro_53 PF07745.8 EPE24284.1 - 9.7e-107 356.5 0.0 1.1e-106 356.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Sec63 PF02889.11 EPE24285.1 - 1.3e-152 507.5 0.2 7.8e-97 324.2 0.3 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EPE24285.1 - 1.4e-52 177.5 0.1 2.6e-28 98.6 0.3 3.2 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE24285.1 - 5.1e-16 58.2 0.0 3.6e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EPE24285.1 - 3.3e-14 53.1 0.0 6.8e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EPE24285.1 - 2e-09 37.6 0.2 0.0084 16.2 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EPE24285.1 - 2.9e-05 23.7 0.0 0.057 13.1 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain IstB_IS21 PF01695.12 EPE24285.1 - 0.0086 15.5 0.0 4.2 6.7 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.1 EPE24285.1 - 0.009 15.4 0.1 0.5 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain bZIP_1 PF00170.16 EPE24286.1 - 5.6e-08 32.6 9.1 6.7e-07 29.1 6.3 2.3 1 1 0 1 1 1 1 bZIP transcription factor Actin PF00022.14 EPE24287.1 - 6.6e-52 176.2 0.0 4.2e-33 114.3 0.0 2.2 2 0 0 2 2 2 2 Actin DASH_Dad4 PF08650.5 EPE24288.1 - 4.5e-27 93.7 5.7 5.2e-27 93.5 4.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.12 EPE24288.1 - 0.0085 16.0 0.4 0.01 15.7 0.3 1.1 1 0 0 1 1 1 1 Granulocyte-macrophage colony-stimulating factor Pecanex_C PF05041.10 EPE24288.1 - 0.023 13.7 0.6 0.025 13.6 0.4 1.0 1 0 0 1 1 1 0 Pecanex protein (C-terminus) DASH_Dad1 PF08649.5 EPE24288.1 - 0.037 13.7 4.2 0.049 13.3 2.9 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 YL1_C PF08265.6 EPE24289.1 - 1.6e-17 62.7 0.1 2.6e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Profilin PF00235.14 EPE24290.1 - 2.1e-42 144.0 0.3 2.3e-42 143.8 0.2 1.0 1 0 0 1 1 1 1 Profilin MannoseP_isomer PF01050.13 EPE24290.1 - 0.055 13.0 0.2 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Ank_2 PF12796.2 EPE24291.1 - 0.0063 16.8 0.0 0.0081 16.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPE24291.1 - 0.01 16.0 0.1 8.1 7.0 0.0 3.1 3 1 0 3 3 3 0 Ankyrin repeat Ank PF00023.25 EPE24291.1 - 0.031 14.0 0.0 6.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat FAD-oxidase_C PF02913.14 EPE24293.1 - 2.5e-63 213.6 0.1 3.6e-63 213.2 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EPE24293.1 - 5.3e-34 116.6 0.0 1e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 EPE24293.1 - 0.006 15.1 0.1 0.019 13.4 0.0 1.7 2 0 0 2 2 2 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Ribosomal_S4e PF00900.15 EPE24294.1 - 2e-32 110.7 0.5 4e-32 109.7 0.3 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EPE24294.1 - 3.2e-18 65.2 3.9 5.9e-18 64.4 2.7 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EPE24294.1 - 7.7e-07 28.4 0.0 1.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EPE24294.1 - 0.0041 16.7 2.0 0.0041 16.7 1.4 3.1 3 0 0 3 3 3 1 KOW motif Semialdhyde_dhC PF02774.13 EPE24295.1 - 3.7e-39 134.4 0.0 5e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EPE24295.1 - 2.2e-30 105.4 0.0 9.6e-30 103.3 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EPE24295.1 - 0.00018 21.3 0.1 0.00071 19.4 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 EPE24295.1 - 0.027 15.0 0.0 0.073 13.6 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 EPE24295.1 - 0.083 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ApbA_C PF08546.6 EPE24296.1 - 2.3e-23 82.5 0.1 4.2e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EPE24296.1 - 9.1e-09 34.9 0.0 2.1e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PXB PF12828.2 EPE24296.1 - 0.0061 16.1 0.1 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 PX-associated Sas10_Utp3 PF04000.10 EPE24297.1 - 1.6e-18 66.6 0.4 3.9e-18 65.4 0.3 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family SR-25 PF10500.4 EPE24297.1 - 3.2 7.1 31.1 1.1 8.7 19.7 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2076 PF09849.4 EPE24298.1 - 3.3e-08 33.8 10.6 3.9e-08 33.6 7.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EPE24298.1 - 1.9e-06 27.5 4.1 2.8e-06 27.1 2.8 1.2 1 0 0 1 1 1 1 CHCH domain Bindin PF02084.10 EPE24298.1 - 9.5 6.1 8.8 6.9 6.6 5.5 1.3 1 1 0 1 1 1 0 Bindin WD40 PF00400.27 EPE24299.1 - 2.7e-21 74.5 9.6 2.2e-06 27.2 0.4 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_3 PF13570.1 EPE24299.1 - 0.036 14.3 0.8 8.4 6.8 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Cytochrom_D1 PF02239.11 EPE24299.1 - 0.04 12.2 0.4 2.7 6.1 0.0 3.3 4 0 0 4 4 4 0 Cytochrome D1 heme domain CDC27 PF09507.5 EPE24299.1 - 0.4 9.8 6.6 0.69 9.0 4.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PD40 PF07676.7 EPE24299.1 - 0.47 10.1 0.0 0.47 10.1 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat CDC45 PF02724.9 EPE24299.1 - 5.5 4.9 8.4 7.8 4.3 5.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EPE24299.1 - 6.2 6.0 13.1 11 5.2 9.1 1.3 1 0 0 1 1 1 0 SDA1 Methyltransf_11 PF08241.7 EPE24300.1 - 1.8e-16 60.3 0.0 2.8e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE24300.1 - 7.3e-14 52.3 0.0 1.1e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE24300.1 - 2.9e-13 49.8 0.0 3.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE24300.1 - 1.2e-12 47.6 0.0 1.4e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE24300.1 - 1.4e-12 47.9 0.0 2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE24300.1 - 4.3e-12 46.2 0.0 6.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE24300.1 - 7.7e-10 38.8 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPE24300.1 - 7e-08 31.8 0.0 8.4e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EPE24300.1 - 1e-07 31.4 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EPE24300.1 - 1.8e-07 30.5 0.0 3.2e-07 29.7 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 EPE24300.1 - 0.00059 19.1 0.0 0.19 11.0 0.0 2.7 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain TehB PF03848.9 EPE24300.1 - 0.0006 19.0 0.0 0.001 18.2 0.0 1.3 1 1 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.15 EPE24300.1 - 0.0013 17.8 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 EPE24300.1 - 0.0024 17.3 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_PK PF05891.7 EPE24300.1 - 0.0026 17.0 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase AviRa PF11599.3 EPE24300.1 - 0.048 12.6 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa UPF0146 PF03686.8 EPE24300.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) 3HCDH_N PF02737.13 EPE24300.1 - 0.17 11.5 0.0 0.74 9.4 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ras PF00071.17 EPE24301.1 - 6.2e-46 155.7 0.0 7.7e-46 155.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE24301.1 - 5.9e-11 42.9 0.0 9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein RRM_1 PF00076.17 EPE24302.1 - 7.1e-09 35.1 0.0 2.1e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE24302.1 - 2.3e-08 33.8 0.0 4.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CFEM PF05730.6 EPE24303.1 - 2.8e-10 39.8 7.8 3.9e-10 39.4 5.4 1.2 1 0 0 1 1 1 1 CFEM domain CMS1 PF14617.1 EPE24304.1 - 1.6e-95 318.9 3.1 1.9e-95 318.7 2.2 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EPE24304.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF3192 PF11399.3 EPE24304.1 - 0.088 12.7 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3192) CENP-T PF15511.1 EPE24305.1 - 1.5e-93 314.3 13.6 1.5e-93 314.3 9.5 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EPE24305.1 - 3.8e-06 26.9 0.0 6.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EPE24305.1 - 0.023 14.8 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPE24305.1 - 0.026 14.5 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SURF1 PF02104.10 EPE24306.1 - 1e-65 221.5 0.0 1.2e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 EPE24307.1 - 4.2e-11 42.7 0.0 8e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain Myb_DNA-bind_6 PF13921.1 EPE24308.1 - 2.2e-13 50.1 0.1 1.1e-05 25.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPE24308.1 - 2.6e-13 49.8 0.2 4.4e-07 29.8 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.5 EPE24308.1 - 0.0021 17.7 0.2 0.79 9.4 0.0 2.4 2 0 0 2 2 2 2 SLIDE YbjM PF11045.3 EPE24309.1 - 0.21 11.3 2.0 0.35 10.6 0.6 1.8 1 1 1 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae SET PF00856.23 EPE24310.1 - 7.6e-08 32.8 0.0 1.1e-06 29.0 0.0 2.3 2 0 0 2 2 2 1 SET domain UbiA PF01040.13 EPE24311.1 - 6e-07 28.9 4.6 9.6e-07 28.2 3.0 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 EPE24312.1 - 4.2e-25 88.1 0.0 5.9e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EPE24313.1 - 2.6e-10 40.2 0.0 9e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE24313.1 - 1.1e-07 32.2 0.0 9.8e-07 29.1 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE24313.1 - 2.5e-06 28.0 0.0 2.3e-05 24.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE24313.1 - 3.1e-06 27.5 0.0 1.3e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE24313.1 - 3.4e-06 26.7 0.0 1.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE24313.1 - 0.15 12.4 0.0 4.8 7.5 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Abhydrolase_6 PF12697.2 EPE24314.1 - 4.6e-20 72.4 0.0 5.6e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE24314.1 - 4.3e-08 33.0 0.0 5.5e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE24314.1 - 0.079 12.8 0.0 0.33 10.8 0.0 2.1 2 1 1 3 3 3 0 Putative lysophospholipase Methyltransf_23 PF13489.1 EPE24315.1 - 1.6e-05 24.6 0.0 5.8e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE24315.1 - 3.3e-05 23.5 0.0 0.00028 20.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE24315.1 - 0.00012 22.4 0.0 0.0012 19.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE24315.1 - 0.00069 20.1 0.0 0.0063 17.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 EPE24315.1 - 0.0042 16.4 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_11 PF08241.7 EPE24315.1 - 0.033 14.6 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.7 EPE24315.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Epimerase PF01370.16 EPE24317.1 - 1e-45 156.0 0.0 1.4e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EPE24317.1 - 9.7e-25 86.2 0.0 1.8e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EPE24317.1 - 5.1e-16 58.1 0.0 1.1e-15 57.0 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EPE24317.1 - 1.6e-13 50.2 0.0 3.8e-13 48.9 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 EPE24317.1 - 5.9e-13 49.0 0.0 8.6e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPE24317.1 - 1.3e-12 47.2 0.0 4.2e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EPE24317.1 - 5e-10 39.3 0.0 8.8e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EPE24317.1 - 8.5e-08 31.4 0.0 6.6e-07 28.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EPE24317.1 - 2.6e-06 27.5 0.0 4.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE24317.1 - 0.0013 18.0 0.0 0.19 10.9 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EPE24317.1 - 0.0046 16.3 0.1 0.0084 15.5 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EPE24317.1 - 0.0095 14.8 0.1 0.017 14.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Saccharop_dh PF03435.13 EPE24317.1 - 0.07 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Thrombin_light PF09396.5 EPE24317.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Thrombin light chain Sad1_UNC PF07738.8 EPE24319.1 - 3.4e-09 36.5 0.2 7.6e-08 32.2 0.0 2.6 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal CorA PF01544.13 EPE24319.1 - 0.058 12.4 0.6 0.099 11.6 0.4 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HMG_box PF00505.14 EPE24319.1 - 1.3 9.3 5.9 3.1 8.1 0.2 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box DEAD PF00270.24 EPE24320.1 - 1.2e-44 151.7 0.1 2.4e-44 150.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EPE24320.1 - 6.2e-25 86.5 0.1 1.4e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EPE24320.1 - 8.1e-22 76.8 0.0 1.8e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE24320.1 - 0.00083 19.2 1.3 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPE24320.1 - 0.0076 15.0 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain PAPS_reduct PF01507.14 EPE24321.1 - 3.4e-29 101.8 0.0 1.3e-19 70.7 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family MFS_1 PF07690.11 EPE24323.1 - 4.7e-53 180.1 52.0 7.9e-47 159.6 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE24323.1 - 2.1e-10 39.5 21.8 2.3e-05 23.0 5.2 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.15 EPE24323.1 - 0.00011 20.3 0.5 0.028 12.4 0.8 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EPE24323.1 - 0.26 9.3 11.2 0.022 12.9 2.4 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector DEAD PF00270.24 EPE24324.1 - 3.1e-45 153.6 0.0 5.6e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBP10CT PF08147.7 EPE24324.1 - 2.6e-23 81.5 4.3 7.8e-23 80.0 3.0 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 EPE24324.1 - 6.3e-21 74.0 0.0 5.7e-20 70.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain BSD PF03909.12 EPE24324.1 - 0.12 12.1 0.2 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 BSD domain Pro-kuma_activ PF09286.6 EPE24325.1 - 1.2e-43 148.6 0.1 2.6e-43 147.4 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain RPA_C PF08784.6 EPE24326.1 - 3.8e-21 75.4 0.1 3.8e-21 75.4 0.1 2.2 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EPE24326.1 - 8.8e-05 22.2 0.1 0.00021 21.0 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Acetyltransf_7 PF13508.1 EPE24327.1 - 1.2e-07 31.8 0.3 1.9e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE24327.1 - 1.7e-05 24.7 0.1 3e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EPE24327.1 - 0.0038 17.0 0.2 0.069 13.0 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain NUDIX PF00293.23 EPE24328.1 - 2.1e-28 98.6 0.0 3.2e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain HEAT PF02985.17 EPE24329.1 - 0.00025 20.8 0.7 2 8.7 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Arm_2 PF04826.8 EPE24329.1 - 0.008 15.3 1.4 2.6 7.0 0.2 2.3 2 0 0 2 2 2 2 Armadillo-like Arm PF00514.18 EPE24329.1 - 0.012 15.4 4.2 2 8.3 0.1 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 EPE24329.1 - 0.023 15.0 0.0 3.4 8.1 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Apo-CIII PF05778.7 EPE24329.1 - 0.083 12.2 0.2 0.21 10.9 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) HEAT_EZ PF13513.1 EPE24329.1 - 0.15 12.6 4.2 8.9 6.9 0.1 4.2 4 0 0 4 4 4 0 HEAT-like repeat Daxx PF03344.10 EPE24329.1 - 0.92 7.9 6.2 1.2 7.4 4.3 1.2 1 0 0 1 1 1 0 Daxx Family Metallophos PF00149.23 EPE24331.1 - 2.6e-36 124.9 0.3 5.2e-29 101.0 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase TACC PF05010.9 EPE24333.1 - 0.018 14.8 0.9 0.028 14.2 0.6 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF605 PF04652.11 EPE24333.1 - 0.28 10.5 10.8 0.31 10.3 7.5 1.1 1 0 0 1 1 1 0 Vta1 like FCH PF00611.18 EPE24334.1 - 0.0042 17.2 4.2 0.016 15.3 2.9 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DnaJ PF00226.26 EPE24335.1 - 1.4e-13 50.3 0.4 1.4e-13 50.3 0.3 2.3 3 0 0 3 3 3 1 DnaJ domain ADH_zinc_N PF00107.21 EPE24337.1 - 7.1e-30 103.2 0.1 1.1e-29 102.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE24337.1 - 3e-16 60.4 0.0 9.9e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE24337.1 - 0.0014 18.3 0.5 0.021 14.5 0.1 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EPE24337.1 - 0.012 15.2 0.1 0.026 14.0 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EPE24337.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.13 EPE24338.1 - 2.6e-24 85.4 0.0 8e-24 83.9 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Polyketide_cyc2 PF10604.4 EPE24339.1 - 0.073 13.2 0.3 0.18 11.9 0.2 1.9 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Fungal_trans PF04082.13 EPE24340.1 - 1e-44 152.3 0.1 1.6e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE24340.1 - 6e-09 35.6 7.9 1.3e-08 34.6 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE24341.1 - 4.8e-46 157.0 18.1 4.8e-46 157.0 12.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE24341.1 - 8.5e-15 54.2 2.3 8.5e-15 54.2 1.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EPE24341.1 - 4e-05 22.0 1.8 6.4e-05 21.3 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EPE24341.1 - 4.3e-05 21.8 0.8 7.1e-05 21.1 0.6 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 EPE24341.1 - 0.26 9.2 3.6 0.21 9.6 0.8 2.0 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pyr_redox_3 PF13738.1 EPE24342.1 - 3.2e-20 73.0 0.1 2.4e-16 60.4 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE24342.1 - 2.3e-16 60.2 0.0 1.7e-11 44.4 0.0 2.6 1 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE24342.1 - 1.7e-12 46.3 0.4 1e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EPE24342.1 - 6.1e-09 35.7 0.0 1.9e-07 31.0 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EPE24342.1 - 9.4e-09 34.6 0.0 1.2e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EPE24342.1 - 1.2e-06 27.7 0.5 0.061 12.2 0.0 3.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPE24342.1 - 1.2e-05 25.6 0.0 0.21 12.0 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE24342.1 - 2.5e-05 24.0 2.2 3.9 7.2 0.0 4.1 3 1 1 4 4 4 3 FAD-NAD(P)-binding Thi4 PF01946.12 EPE24342.1 - 0.0021 17.1 1.8 0.02 13.9 0.2 2.4 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 EPE24342.1 - 0.0029 16.5 0.0 0.0057 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EPE24342.1 - 0.0059 16.8 0.0 4 7.7 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding GIDA PF01134.17 EPE24342.1 - 0.0084 15.0 0.2 4 6.2 0.0 3.3 3 1 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 EPE24342.1 - 0.013 13.9 0.4 1.5 7.2 0.0 3.3 4 0 0 4 4 4 0 HI0933-like protein FAD_binding_3 PF01494.14 EPE24342.1 - 0.27 10.2 2.9 0.21 10.5 0.1 2.1 3 0 0 3 3 3 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EPE24342.1 - 0.41 9.7 1.3 0.73 8.9 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain tRNA_bind PF01588.15 EPE24343.1 - 1.1e-21 76.4 2.0 4.3e-21 74.5 0.2 2.5 2 1 0 2 2 2 1 Putative tRNA binding domain GST_C_3 PF14497.1 EPE24343.1 - 2.2e-07 31.2 0.0 1.3e-06 28.7 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPE24343.1 - 0.0079 16.1 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPE24343.1 - 0.052 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF530 PF04409.7 EPE24343.1 - 0.12 10.4 0.1 0.16 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) DUF3435 PF11917.3 EPE24344.1 - 3.1e-20 72.3 0.1 4.5e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_4 PF13894.1 EPE24344.1 - 2.1 8.8 8.8 13 6.3 0.2 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE24344.1 - 4.7 7.7 12.6 5.2 7.6 0.1 5.3 5 0 0 5 5 5 0 Zinc finger, C2H2 type Pyridox_oxase_2 PF12766.2 EPE24346.1 - 7.5e-24 83.9 0.0 1.3e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4448 PF14610.1 EPE24347.1 - 0.021 14.3 1.4 0.031 13.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Herpes_BLRF2 PF05812.7 EPE24348.1 - 0.021 14.6 0.1 0.023 14.4 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Imm24 PF15570.1 EPE24348.1 - 0.083 12.6 0.0 0.083 12.6 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 24 DUF1581 PF07619.6 EPE24349.1 - 0.018 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) HATPase_c PF02518.21 EPE24350.1 - 1.4e-24 85.9 0.0 2.6e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE24350.1 - 7.8e-20 70.9 0.3 1.5e-19 70.0 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EPE24350.1 - 9.3e-10 38.8 0.0 7.6e-09 35.8 0.0 2.6 2 0 0 2 2 2 1 PAS domain HisKA PF00512.20 EPE24350.1 - 3.7e-08 33.2 0.2 1.5e-07 31.3 0.1 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EPE24350.1 - 4.9e-06 26.2 0.0 1.5e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EPE24350.1 - 4.1e-05 23.2 0.0 0.00023 20.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain GAF_2 PF13185.1 EPE24350.1 - 0.00014 22.3 0.0 0.0005 20.5 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EPE24350.1 - 0.00038 20.5 0.0 0.0042 17.1 0.0 2.4 2 0 0 2 2 2 1 GAF domain PAS_4 PF08448.5 EPE24350.1 - 0.02 14.9 0.0 0.24 11.4 0.0 2.8 2 0 0 2 2 2 0 PAS fold HATPase_c_3 PF13589.1 EPE24350.1 - 0.028 14.0 0.0 0.081 12.5 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.6 EPE24350.1 - 0.043 13.8 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 PAS fold ADH_N PF08240.7 EPE24351.1 - 3.9e-11 42.6 0.1 1.1e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE24351.1 - 1.1e-08 34.6 0.0 1.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Snf7 PF03357.16 EPE24352.1 - 2.7e-17 62.6 10.6 2.7e-17 62.6 7.3 2.1 1 1 1 2 2 2 1 Snf7 DRY_EERY PF09750.4 EPE24352.1 - 2.8 8.0 9.7 6.4 6.9 6.8 1.5 1 0 0 1 1 1 0 Alternative splicing regulator DUF607 PF04678.8 EPE24352.1 - 6.8 6.5 17.1 0.34 10.7 4.2 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF607 zf-C3HC4 PF00097.20 EPE24353.1 - 6.6e-08 32.0 13.8 6.6e-08 32.0 9.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE24353.1 - 1.8e-07 30.7 17.3 3.5e-07 29.8 9.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPE24353.1 - 2.8e-07 30.4 16.6 1.2e-06 28.4 9.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE24353.1 - 6.1e-07 29.0 14.2 2.7e-06 26.9 6.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE24353.1 - 4.5e-06 26.3 16.9 6.9e-06 25.7 8.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 EPE24353.1 - 0.00048 19.8 7.1 0.00048 19.8 5.0 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EPE24353.1 - 0.0007 19.1 6.6 0.0007 19.1 4.6 2.8 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EPE24353.1 - 0.0016 18.2 17.0 0.0019 18.0 9.3 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPE24353.1 - 0.0024 17.5 8.9 0.0024 17.5 6.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EPE24353.1 - 0.0038 17.2 5.0 0.0038 17.2 3.5 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger Mob_synth_C PF06463.8 EPE24353.1 - 0.062 12.9 3.0 0.19 11.4 2.1 1.8 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-Apc11 PF12861.2 EPE24353.1 - 0.23 11.3 5.2 0.11 12.2 1.9 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger CDC27 PF09507.5 EPE24354.1 - 4.8e-93 312.7 28.2 5.7e-93 312.4 19.6 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DEAD PF00270.24 EPE24355.1 - 6.2e-40 136.4 0.1 1.1e-39 135.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE24355.1 - 5.1e-21 74.3 0.0 1.1e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EPE24355.1 - 1.3e-16 59.8 0.0 2.6e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EPE24355.1 - 0.00025 20.9 0.0 0.00047 20.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPE24355.1 - 0.0058 15.4 0.0 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Pantoate_ligase PF02569.10 EPE24356.1 - 5.6e-82 274.6 0.0 9.9e-82 273.8 0.0 1.4 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Fungal_trans PF04082.13 EPE24357.1 - 3.2e-09 36.0 0.2 7e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF221 PF02714.10 EPE24358.1 - 2.2e-111 371.8 23.3 2.2e-111 371.8 16.1 2.5 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPE24358.1 - 4.9e-41 139.8 0.3 4.9e-41 139.8 0.2 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EPE24358.1 - 1.9e-31 107.7 0.1 1.4e-30 105.0 0.0 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EPE24358.1 - 1.5e-18 67.0 0.0 2.4e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Git3 PF11710.3 EPE24359.1 - 5.2e-74 248.1 18.2 5.2e-74 248.1 12.6 1.9 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EPE24359.1 - 2.7e-27 94.3 0.9 2.7e-27 94.3 0.6 2.6 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EPE24359.1 - 7.5e-06 25.2 0.0 1.2e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DHHA2 PF02833.9 EPE24361.1 - 7.5e-20 71.4 0.0 1.4e-19 70.5 0.0 1.4 1 1 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EPE24362.1 - 4.9e-10 39.2 0.1 1.4e-09 37.7 0.1 1.6 1 1 0 1 1 1 1 DHH family AMP-binding PF00501.23 EPE24363.1 - 4.5e-23 81.3 0.0 7.6e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPE24363.1 - 1.9e-21 76.1 0.0 2.8e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EPE24363.1 - 2.4e-07 30.8 0.0 8.6e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 EPE24363.1 - 4.1e-07 29.6 0.0 6.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Flavin_Reduct PF01613.13 EPE24363.1 - 0.087 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Flavin reductase like domain adh_short PF00106.20 EPE24363.1 - 0.31 10.9 0.5 2 8.3 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase DHQ_synthase PF01761.15 EPE24364.1 - 3.7e-54 183.3 0.0 5.2e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EPE24364.1 - 7.8e-14 51.5 0.0 1.2e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.12 EPE24365.1 - 1.4e-11 43.8 0.0 1.9e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EPE24365.1 - 1.7e-09 38.4 0.0 2.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain SIS_2 PF13580.1 EPE24365.1 - 0.064 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 SIS domain ATP-grasp_4 PF13535.1 EPE24366.1 - 6.7e-07 29.2 0.0 2.3e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPE24366.1 - 5.1e-06 25.4 0.0 4.7e-05 22.2 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon MOR2-PAG1_N PF14222.1 EPE24367.1 - 2.6e-225 749.3 0.0 4.6e-225 748.4 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EPE24367.1 - 3.7e-95 318.6 0.2 1.2e-94 316.9 0.0 2.0 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EPE24367.1 - 9e-35 119.6 13.4 3.4e-14 51.4 0.1 4.1 2 1 1 3 3 3 3 Cell morphogenesis central region FAD_binding_1 PF00667.15 EPE24368.1 - 2e-60 203.9 0.0 3.1e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EPE24368.1 - 6.9e-34 116.9 0.8 1.8e-33 115.5 0.5 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EPE24368.1 - 4.4e-23 81.9 0.1 9.2e-22 77.6 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EPE24368.1 - 0.014 15.3 0.1 0.2 11.6 0.0 2.5 1 1 1 2 2 2 0 Flavodoxin domain RRM_1 PF00076.17 EPE24369.1 - 2.9e-23 81.2 0.0 1.6e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE24369.1 - 1e-15 57.4 0.0 4.7e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE24369.1 - 0.002 17.9 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.17 EPE24370.1 - 1.2e-41 142.1 0.1 6.8e-40 136.4 0.1 2.2 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EPE24370.1 - 4.6e-30 103.5 0.0 1.1e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EPE24370.1 - 4.4e-08 33.1 0.0 0.00072 19.3 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EPE24370.1 - 1e-05 24.7 0.0 0.0014 17.7 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sporozoite_P67 PF05642.6 EPE24370.1 - 0.025 12.4 5.3 0.034 12.0 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CobT PF06213.7 EPE24370.1 - 0.11 11.5 9.3 0.17 11.0 6.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 EPE24370.1 - 0.26 10.5 6.2 0.38 9.9 4.3 1.1 1 0 0 1 1 1 0 NOA36 protein PC_rep PF01851.17 EPE24371.1 - 3.6e-23 80.4 20.3 7.5e-07 29.0 0.2 10.1 11 0 0 11 11 11 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EPE24371.1 - 6.6e-11 42.3 2.2 0.00014 22.0 0.1 4.5 4 2 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EPE24371.1 - 0.047 13.7 0.0 3 8.1 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat DNA_mis_repair PF01119.14 EPE24372.1 - 3.6e-33 113.5 0.1 6.2e-33 112.7 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EPE24372.1 - 8.3e-15 54.6 0.0 1.8e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EPE24372.1 - 2.1e-09 37.0 0.0 4.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GMC_oxred_N PF00732.14 EPE24373.1 - 3.1e-48 164.4 0.0 6.9e-47 160.0 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE24373.1 - 4.6e-21 75.6 0.0 9.6e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EPE24373.1 - 5e-05 23.2 0.1 0.00013 21.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE24373.1 - 7.4e-05 21.8 0.2 0.0003 19.7 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE24373.1 - 0.018 13.9 0.0 0.097 11.4 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EPE24373.1 - 0.021 13.7 0.1 0.031 13.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein MatE PF01554.13 EPE24374.1 - 9.5e-55 184.6 24.5 9.7e-28 96.8 4.4 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EPE24374.1 - 0.0015 18.3 6.5 0.0015 18.3 4.5 4.0 1 1 3 4 4 4 1 Polysaccharide biosynthesis C-terminal domain PRKCSH_1 PF13015.1 EPE24374.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein DUF202 PF02656.10 EPE24375.1 - 3.9e-18 65.4 1.1 2.5e-17 62.8 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) TctB PF07331.6 EPE24375.1 - 0.12 12.0 4.0 0.17 11.4 2.7 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family SH3_1 PF00018.23 EPE24376.1 - 7.7e-27 92.4 0.0 8.8e-13 47.4 0.0 2.9 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EPE24376.1 - 7.4e-16 57.4 0.1 8.4e-07 28.4 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 EPE24376.1 - 3.2e-14 52.6 0.0 6.1e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EPE24376.1 - 2.2e-12 46.2 0.0 2.3e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 EPE24376.1 - 1e-06 28.3 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 PB1 domain Pex14_N PF04695.8 EPE24376.1 - 1.9 8.4 10.5 0.31 11.1 1.9 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DBD_Tnp_Mut PF03108.10 EPE24377.1 - 5.7e-13 48.2 0.0 1.2e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 MuDR family transposase DUF1996 PF09362.5 EPE24378.1 - 3.3e-55 187.3 1.3 4.2e-55 186.9 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SAC3_GANP PF03399.11 EPE24379.1 - 2e-68 229.9 0.1 3.3e-68 229.2 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPE24379.1 - 0.013 15.3 0.0 0.038 13.7 0.0 1.7 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 EAP30 PF04157.11 EPE24380.1 - 2.1e-52 177.5 0.0 2.7e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EPE24380.1 - 4e-27 93.8 0.0 6.4e-27 93.2 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EPE24380.1 - 0.00097 18.6 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 EPE24380.1 - 0.0011 18.5 4.9 0.0026 17.2 0.3 2.7 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 EPE24380.1 - 0.036 13.1 8.3 0.19 10.8 0.9 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DZR PF12773.2 EPE24380.1 - 0.083 12.7 1.5 0.2 11.5 0.2 2.0 2 0 0 2 2 2 0 Double zinc ribbon FYVE PF01363.16 EPE24381.1 - 0.0014 18.5 0.4 0.0022 17.8 0.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_UBOX PF13445.1 EPE24381.1 - 0.023 14.3 0.4 0.062 13.0 0.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EPE24381.1 - 0.64 10.0 6.1 2.4 8.2 4.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SKG6 PF08693.5 EPE24382.1 - 0.00071 18.8 0.2 0.0011 18.1 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain GRA6 PF05084.8 EPE24382.1 - 0.0028 17.1 0.1 0.003 17.1 0.1 1.0 1 0 0 1 1 1 1 Granule antigen protein (GRA6) Herpes_gE PF02480.11 EPE24382.1 - 0.013 13.7 0.0 0.015 13.5 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4448 PF14610.1 EPE24382.1 - 0.03 13.8 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EPE24382.1 - 0.03 14.0 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family RAMP4 PF06624.7 EPE24382.1 - 0.041 13.4 0.4 0.078 12.5 0.0 1.7 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DUF1191 PF06697.7 EPE24382.1 - 0.097 11.4 0.0 0.099 11.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF3377 PF11857.3 EPE24382.1 - 0.12 11.9 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Sarcoglycan_2 PF05510.8 EPE24382.1 - 0.15 10.3 0.0 0.16 10.2 0.0 1.0 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon TadE PF07811.7 EPE24382.1 - 1.6 8.6 5.7 2.4 8.1 4.0 1.2 1 0 0 1 1 1 0 TadE-like protein NAD_binding_4 PF07993.7 EPE24385.1 - 8.5e-32 110.0 0.0 1.3e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EPE24385.1 - 3.7e-28 98.0 0.0 8.2e-28 96.9 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EPE24385.1 - 3.3e-06 26.7 0.0 7.8e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EPE24385.1 - 0.0006 20.0 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EPE24385.1 - 0.0075 16.2 0.1 0.096 12.5 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE24385.1 - 0.064 12.9 0.2 0.51 9.9 0.0 2.3 2 0 0 2 2 2 0 KR domain RmlD_sub_bind PF04321.12 EPE24385.1 - 0.086 11.7 0.0 2.2 7.1 0.0 2.6 2 1 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EPE24385.1 - 0.095 11.5 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sec7 PF01369.15 EPE24386.1 - 3.8e-62 209.3 2.5 4.3e-62 209.1 0.2 2.3 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 EPE24386.1 - 1.1e-37 129.0 8.2 7.8e-20 70.9 0.1 3.7 2 1 1 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EPE24386.1 - 5.9e-32 109.0 0.6 1.4e-30 104.6 0.1 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 EPE24387.1 - 1.9e-73 246.5 0.0 2.4e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EPE24387.1 - 4.6e-18 64.6 2.9 4.7e-18 64.6 0.5 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EPE24387.1 - 1.2e-06 27.9 0.6 2.5e-06 27.0 0.4 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EPE24387.1 - 0.07 12.8 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like DUF3614 PF12267.3 EPE24387.1 - 0.41 10.9 0.0 0.41 10.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) CHCH PF06747.8 EPE24388.1 - 2.1e-07 30.6 2.1 4.1e-07 29.7 1.5 1.5 1 0 0 1 1 1 1 CHCH domain Mnd1 PF03962.10 EPE24388.1 - 4.1 7.0 11.0 0.89 9.1 1.7 2.2 2 0 0 2 2 2 0 Mnd1 family Med2 PF11214.3 EPE24388.1 - 4.9 7.2 9.3 0.28 11.2 2.5 1.8 2 0 0 2 2 2 0 Mediator complex subunit 2 GCK PF07802.6 EPE24388.1 - 9.9 6.3 7.3 0.66 10.1 1.4 1.8 2 0 0 2 2 2 0 GCK domain TPK_catalytic PF04263.11 EPE24389.1 - 1.4e-26 92.5 0.0 1.8e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EPE24389.1 - 1.9e-21 75.5 0.4 2.8e-21 74.9 0.3 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Fer4_3 PF12798.2 EPE24391.1 - 3.4 8.4 6.6 0.5 11.0 1.2 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 EPE24391.1 - 6.1 6.9 7.5 31 4.7 5.2 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF4375 PF14300.1 EPE24392.1 - 0.015 15.3 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Ribosomal_L38e PF01781.13 EPE24392.1 - 0.055 13.2 2.0 0.15 11.8 1.3 1.9 1 1 0 1 1 1 0 Ribosomal L38e protein family Cytochrome_C7 PF14522.1 EPE24394.1 - 0.21 11.2 4.8 5.1 6.8 0.5 2.4 2 0 0 2 2 2 0 Cytochrome c7 Rad4 PF03835.10 EPE24395.1 - 1.3e-25 89.4 0.3 1.3e-25 89.4 0.2 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EPE24395.1 - 2.2e-24 84.9 0.0 3.9e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EPE24395.1 - 2.7e-19 68.4 0.3 6.8e-19 67.1 0.2 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EPE24395.1 - 6.2e-14 52.0 2.9 1.2e-13 51.1 0.3 2.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EPE24395.1 - 0.026 14.7 0.0 0.073 13.2 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily Acid_PPase PF12689.2 EPE24396.1 - 3.6e-67 225.2 0.0 4.2e-67 224.9 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EPE24396.1 - 0.093 12.9 0.6 1 9.5 0.0 2.3 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Acetyltransf_1 PF00583.19 EPE24397.1 - 2.4e-13 49.8 0.0 4.8e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE24397.1 - 2.3e-12 47.0 0.0 7.2e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPE24397.1 - 9.4e-09 35.3 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE24397.1 - 5e-06 26.3 0.0 9.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EPE24397.1 - 1.6e-05 24.5 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EPE24397.1 - 4.4e-05 23.3 0.1 7.5e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EPE24397.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 EPE24398.1 - 1.1e-44 152.6 56.9 1.3e-43 149.1 39.4 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE24398.1 - 2.1e-21 75.8 48.6 8.6e-21 73.8 33.7 1.7 1 1 0 1 1 1 1 Amino acid permease adh_short PF00106.20 EPE24399.1 - 1.6e-13 50.8 2.1 2.4e-13 50.3 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE24399.1 - 2.7e-07 30.6 0.1 3.7e-07 30.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE24399.1 - 3.8e-06 26.7 2.0 4.7e-06 26.3 1.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE24399.1 - 0.0046 16.4 0.2 0.012 15.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE24399.1 - 0.17 11.8 1.5 0.79 9.7 1.1 2.1 1 1 0 1 1 1 0 NADH(P)-binding FYVE PF01363.16 EPE24400.1 - 2.1e-22 78.7 27.9 1.2e-16 60.3 5.7 3.1 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 EPE24400.1 - 9.3e-05 22.4 6.1 0.0029 17.7 0.1 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 EPE24400.1 - 0.00018 21.3 3.1 0.00018 21.3 2.2 4.0 5 1 0 5 5 5 2 AN1-like Zinc finger zf-C2H2_2 PF12756.2 EPE24400.1 - 0.032 14.3 10.7 0.13 12.3 0.0 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EPE24400.1 - 2.4 8.4 17.5 0.19 11.9 0.4 5.2 6 0 0 6 6 6 0 Zinc-finger of C2H2 type NAD_binding_7 PF13241.1 EPE24401.1 - 1.2e-33 115.4 0.0 2.2e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EPE24401.1 - 9.4e-26 88.9 0.0 1.5e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EPE24401.1 - 2e-12 45.8 0.1 3.8e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 EPE24401.1 - 0.008 16.2 0.1 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EPE24401.1 - 0.038 13.9 0.1 0.078 12.9 0.1 1.5 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 EPE24401.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 EPE24401.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.16 EPE24401.1 - 0.33 10.7 2.6 0.36 10.6 0.0 2.2 2 1 1 3 3 3 0 ThiF family SUR7 PF06687.7 EPE24402.1 - 2.3e-29 102.4 3.2 2.7e-29 102.2 2.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EPE24402.1 - 0.00014 21.8 1.2 0.00014 21.8 0.8 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 DUF4516 PF14990.1 EPE24402.1 - 0.44 10.1 2.8 9.1 5.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) DUF1218 PF06749.7 EPE24402.1 - 1.6 9.2 8.3 3.6 8.1 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) DUF2514 PF10721.4 EPE24403.1 - 0.048 13.3 6.2 0.052 13.2 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) VIT1 PF01988.14 EPE24403.1 - 0.051 13.0 0.6 0.061 12.8 0.4 1.2 1 0 0 1 1 1 0 VIT family ParA PF10609.4 EPE24404.1 - 2.8e-36 123.2 0.1 8.1e-36 121.7 0.0 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EPE24404.1 - 1.3e-17 63.8 0.0 2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EPE24404.1 - 2.8e-05 24.1 0.0 0.00011 22.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EPE24404.1 - 2.8e-05 23.3 0.2 0.00098 18.2 0.1 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EPE24404.1 - 0.00088 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 EPE24404.1 - 0.0012 17.9 0.0 0.0031 16.6 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EPE24404.1 - 0.0018 17.8 0.1 0.2 11.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EPE24404.1 - 0.015 14.4 0.1 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 EPE24404.1 - 0.017 13.9 0.2 0.026 13.4 0.1 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Fer4_NifH PF00142.13 EPE24404.1 - 0.021 14.0 0.0 0.54 9.3 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.1 EPE24404.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain VirE PF05272.6 EPE24404.1 - 0.05 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E Zn_Tnp_IS1595 PF12760.2 EPE24404.1 - 0.068 12.9 0.1 0.22 11.3 0.0 1.8 2 0 0 2 2 1 0 Transposase zinc-ribbon domain RNA_helicase PF00910.17 EPE24404.1 - 0.071 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EPE24404.1 - 0.093 12.4 0.8 0.75 9.5 0.0 2.4 2 1 0 2 2 2 0 Part of AAA domain SRP54 PF00448.17 EPE24404.1 - 0.13 11.6 0.1 0.43 9.9 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EPE24404.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPE24404.1 - 0.2 12.5 0.3 0.41 11.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EPE24404.1 - 0.2 10.4 0.0 1 8.1 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PEMT PF04191.8 EPE24405.1 - 1e-56 189.5 12.3 4.1e-35 120.0 1.8 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase DUF883 PF05957.8 EPE24406.1 - 0.00057 20.2 1.3 0.0011 19.2 0.9 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Cas_Csy4 PF09618.5 EPE24406.1 - 0.016 15.0 0.4 0.021 14.6 0.3 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) DUF3752 PF12572.3 EPE24406.1 - 0.033 14.2 6.3 0.043 13.9 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) NCD2 PF04905.8 EPE24406.1 - 0.051 13.3 1.9 0.071 12.8 1.3 1.1 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) YlqD PF11068.3 EPE24406.1 - 0.17 11.9 2.9 0.23 11.5 2.0 1.1 1 0 0 1 1 1 0 YlqD protein ISG65-75 PF11727.3 EPE24406.1 - 0.31 10.0 5.9 0.42 9.6 4.1 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DNA_pol3_a_NII PF11490.3 EPE24406.1 - 1.3 8.6 6.5 2 8.0 4.5 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Glycophorin_A PF01102.13 EPE24407.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A GHMP_kinases_N PF00288.21 EPE24408.1 - 1.1e-15 57.4 1.5 2.5e-15 56.2 1.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPE24408.1 - 5.5e-06 26.4 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PPR_2 PF13041.1 EPE24409.1 - 1.1e-49 166.2 0.2 3.4e-09 36.5 0.0 13.5 11 2 3 14 14 14 11 PPR repeat family PPR PF01535.15 EPE24409.1 - 2.9e-25 86.4 15.4 0.00021 21.0 0.0 14.1 18 0 0 18 18 18 4 PPR repeat PPR_3 PF13812.1 EPE24409.1 - 7.5e-24 81.9 18.2 0.00023 21.1 0.0 14.6 16 0 0 16 16 16 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 EPE24409.1 - 1.9e-22 78.4 0.4 5.9e-08 32.0 0.0 9.7 11 0 0 11 11 11 3 PPR repeat RPM2 PF08579.6 EPE24409.1 - 0.002 18.2 0.0 0.045 13.8 0.0 3.2 3 1 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.1 EPE24409.1 - 0.015 15.0 0.0 24 5.0 0.0 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PH_5 PF15405.1 EPE24410.1 - 0.4 10.6 3.3 0.9 9.4 2.3 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain DUF605 PF04652.11 EPE24410.1 - 2.7 7.2 18.3 3.1 7.1 12.7 1.0 1 0 0 1 1 1 0 Vta1 like Methyltransf_33 PF10017.4 EPE24413.1 - 4.5e-32 110.5 0.0 7.7e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EPE24413.1 - 4.8e-18 65.4 0.2 7.3e-17 61.5 0.0 2.5 2 1 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EPE24413.1 - 5.7e-08 33.1 0.2 1.4e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 EPE24413.1 - 0.012 15.9 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2020 PF09449.5 EPE24413.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) Nuf2 PF03800.9 EPE24414.1 - 8.4e-42 142.6 2.5 1.3e-41 141.9 0.2 2.2 2 0 0 2 2 2 1 Nuf2 family DUF869 PF05911.6 EPE24414.1 - 0.027 12.7 32.7 0.18 10.0 22.8 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 EPE24414.1 - 0.77 8.8 10.5 0.24 10.5 2.6 2.6 1 1 1 3 3 3 0 Reovirus sigma C capsid protein DivIC PF04977.10 EPE24414.1 - 6.5 6.3 29.9 0.047 13.1 1.3 5.6 4 2 2 6 6 6 0 Septum formation initiator Adaptin_N PF01602.15 EPE24416.1 - 2.1e-109 366.2 0.0 2.7e-109 365.8 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EPE24416.1 - 4.1e-11 43.0 7.1 3.6e-05 23.9 0.0 5.2 4 2 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EPE24416.1 - 1.1e-10 40.6 0.0 0.2 11.8 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EPE24416.1 - 8.6e-05 22.9 4.0 0.11 13.0 0.0 5.1 5 0 0 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EPE24416.1 - 0.00022 21.0 0.0 0.52 10.3 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EPE24416.1 - 0.081 12.7 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HTH_36 PF13730.1 EPE24416.1 - 0.097 12.8 0.0 0.59 10.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain VHS PF00790.14 EPE24416.1 - 0.17 11.4 1.0 29 4.2 0.0 3.5 4 0 0 4 4 4 0 VHS domain CDC45 PF02724.9 EPE24416.1 - 7.7 4.4 17.2 12 3.8 11.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Metallophos PF00149.23 EPE24418.1 - 5.5e-27 94.4 0.3 1.4e-12 47.4 0.2 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase DUF2268 PF10026.4 EPE24418.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Rho_GDI PF02115.12 EPE24419.1 - 2.9e-57 193.3 0.4 3.2e-57 193.1 0.3 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Pkinase PF00069.20 EPE24420.1 - 3e-68 229.7 0.0 4.2e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE24420.1 - 1.2e-30 106.4 0.0 4.9e-29 101.1 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE24420.1 - 0.0085 15.0 0.2 2 7.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EPE24420.1 - 0.0089 15.7 0.1 0.15 11.7 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 EPE24420.1 - 0.02 14.2 0.1 0.037 13.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family DUF3328 PF11807.3 EPE24422.1 - 1.2e-06 28.4 0.0 1.6e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_2 PF13347.1 EPE24423.1 - 5.3e-08 31.6 8.8 5.3e-08 31.6 6.1 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF3328 PF11807.3 EPE24425.1 - 2.8e-24 86.0 3.1 3.6e-24 85.6 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.3 EPE24427.1 - 4.4e-25 88.0 7.9 5.4e-25 87.8 5.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EPE24428.1 - 2e-12 46.8 0.0 1.3e-11 44.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE24428.1 - 0.00039 19.5 0.0 0.00064 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Transp_cyt_pur PF02133.10 EPE24430.1 - 1.1e-16 60.4 37.5 1.7e-16 59.8 26.0 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pec_lyase_C PF00544.14 EPE24431.1 - 1.4e-46 158.5 8.0 2e-46 158.0 5.6 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EPE24431.1 - 0.0002 21.1 14.2 0.0084 15.8 9.8 2.3 1 1 0 1 1 1 1 Right handed beta helix region PPI_Ypi1 PF07491.6 EPE24432.1 - 0.002 17.6 0.0 0.0049 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor Ribonuc_L-PSP PF01042.16 EPE24433.1 - 3.2e-38 130.1 0.0 3.6e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP LCE PF14672.1 EPE24434.1 - 0.068 13.6 0.6 0.072 13.5 0.4 1.2 1 0 0 1 1 1 0 Late cornified envelope Isochorismatase PF00857.15 EPE24435.1 - 1.5e-28 99.9 0.0 3.1e-28 98.8 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family DDE_3 PF13358.1 EPE24436.1 - 2.5e-11 43.5 0.0 4.3e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EPE24436.1 - 8.6e-05 22.5 1.3 0.0001 22.2 0.3 1.6 2 0 0 2 2 2 1 Transposase rve PF00665.21 EPE24436.1 - 0.0055 16.8 0.0 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain HTH_32 PF13565.1 EPE24436.1 - 0.075 13.8 4.9 0.13 13.0 0.2 2.8 3 0 0 3 3 3 0 Homeodomain-like domain zf-RING_3 PF14369.1 EPE24437.1 - 0.043 13.8 0.2 0.13 12.2 0.2 1.8 1 0 0 1 1 1 0 zinc-finger DUF2413 PF10310.4 EPE24438.1 - 7.8e-145 483.0 0.2 9.1e-145 482.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Ank_2 PF12796.2 EPE24439.1 - 1.2e-12 48.0 0.0 0.0019 18.4 0.0 4.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE24439.1 - 5.3e-12 45.8 0.1 0.00013 22.3 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Clr5 PF14420.1 EPE24439.1 - 3.5e-11 42.8 0.5 8.1e-11 41.6 0.4 1.6 1 0 0 1 1 1 1 Clr5 domain Ank_5 PF13857.1 EPE24439.1 - 4.9e-11 42.5 0.9 0.04 14.1 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EPE24439.1 - 4.6e-08 32.4 0.1 0.0033 17.1 0.0 5.7 6 1 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.1 EPE24439.1 - 1.6e-05 24.7 0.6 0.084 13.1 0.0 5.7 7 0 0 7 7 7 1 Ankyrin repeat LicD PF04991.8 EPE24440.1 - 8.2e-34 117.5 6.5 8.2e-34 117.5 4.5 3.2 2 1 0 2 2 2 1 LicD family HC2 PF07382.6 EPE24440.1 - 0.041 13.7 22.5 0.061 13.1 15.6 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 YjgP_YjgQ PF03739.9 EPE24440.1 - 4 6.0 5.0 7.7 5.1 3.4 1.5 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family Slx4 PF09494.5 EPE24441.1 - 1.8e-24 85.2 0.0 3.7e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease Ribosomal_S21e PF01249.13 EPE24442.1 - 3.3e-42 142.3 0.0 3.7e-42 142.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FAD_binding_7 PF03441.9 EPE24443.1 - 1.2e-103 346.1 0.6 1.2e-103 346.1 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EPE24443.1 - 1.5e-39 135.4 0.0 3.7e-39 134.1 0.0 1.7 2 0 0 2 2 2 1 DNA photolyase Usp PF00582.21 EPE24443.1 - 0.015 15.4 0.4 0.03 14.5 0.0 1.7 2 0 0 2 2 2 0 Universal stress protein family Pro_dh PF01619.13 EPE24444.1 - 7.9e-36 123.6 0.0 1.1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Tim17 PF02466.14 EPE24445.1 - 0.0038 17.2 3.8 0.0087 16.0 2.6 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3464 PF11947.3 EPE24445.1 - 0.45 9.9 2.7 0.42 10.0 0.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3464) Reo_sigmaC PF04582.7 EPE24448.1 - 0.097 11.8 3.3 0.37 9.9 0.6 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EPE24448.1 - 0.64 9.8 7.8 4.3 7.1 1.3 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NUDIX PF00293.23 EPE24450.1 - 3.3e-10 39.7 0.0 1.3e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 NUDIX domain Vps53_N PF04100.7 EPE24451.1 - 1.1e-103 347.0 3.2 2e-103 346.1 2.2 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EPE24451.1 - 1.6e-08 33.8 7.4 1.6e-08 33.8 5.1 1.7 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 EPE24451.1 - 7.8e-05 21.4 4.8 0.00014 20.6 3.4 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Rbsn PF11464.3 EPE24451.1 - 0.029 13.9 0.2 0.1 12.2 0.1 1.9 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Snapin_Pallidin PF14712.1 EPE24451.1 - 0.055 13.7 7.0 0.039 14.2 1.6 3.1 1 1 0 2 2 2 0 Snapin/Pallidin PEX-2N PF09263.5 EPE24451.1 - 0.057 13.7 0.2 2 8.7 0.0 2.6 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal Sigma70_ner PF04546.8 EPE24451.1 - 0.1 12.2 2.4 0.14 11.7 1.0 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF904 PF06005.7 EPE24451.1 - 3.3 8.0 7.9 17 5.7 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF904) COG2 PF06148.6 EPE24451.1 - 6.5 6.6 12.6 0.59 9.9 2.1 3.6 3 2 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Renin_r PF07850.9 EPE24452.1 - 0.17 12.2 0.6 0.41 11.0 0.4 1.6 1 0 0 1 1 1 0 Renin receptor-like protein LETM1 PF07766.8 EPE24453.1 - 8.2e-105 349.6 0.1 1.3e-104 348.9 0.1 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EPE24453.1 - 0.00015 21.1 0.0 0.055 13.0 0.0 3.2 3 0 0 3 3 3 2 SAP domain AflR PF08493.5 EPE24453.1 - 1.2 8.0 5.8 2.6 6.9 3.3 1.9 2 0 0 2 2 2 0 Aflatoxin regulatory protein ADK PF00406.17 EPE24454.1 - 1.3e-37 129.0 0.0 3.2e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EPE24454.1 - 1.2e-11 44.0 0.0 2.1e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EPE24454.1 - 2.6e-07 31.0 0.0 8.2e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPE24454.1 - 1.5e-05 24.8 0.0 0.0042 16.9 0.0 2.4 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EPE24454.1 - 7.8e-05 23.4 0.0 0.00028 21.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPE24454.1 - 0.03 13.4 0.0 0.071 12.2 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 EPE24454.1 - 0.031 14.4 0.0 0.68 10.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPE24454.1 - 0.048 13.3 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPE24454.1 - 0.051 13.7 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 EPE24454.1 - 0.14 11.5 0.0 0.73 9.2 0.0 2.1 3 0 0 3 3 3 0 Guanylate kinase Mg_chelatase PF01078.16 EPE24454.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Metallophos PF00149.23 EPE24455.1 - 2.6e-10 40.0 4.0 5.6e-09 35.6 2.7 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase zf-DHHC PF01529.15 EPE24456.1 - 1e-36 125.9 1.9 2e-36 125.0 1.3 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase NnrU PF07298.6 EPE24456.1 - 0.0085 15.4 3.2 0.013 14.8 2.2 1.3 1 0 0 1 1 1 1 NnrU protein Transglut_core3 PF13471.1 EPE24456.1 - 0.053 13.3 0.8 0.053 13.3 0.5 1.8 2 0 0 2 2 2 0 Transglutaminase-like superfamily DZR PF12773.2 EPE24456.1 - 0.89 9.4 8.9 1.5 8.6 6.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon Spt4 PF06093.8 EPE24456.1 - 1.6 8.6 5.4 3.3 7.6 3.7 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger MFS_1 PF07690.11 EPE24457.1 - 2.3e-40 138.3 64.2 7.5e-39 133.4 41.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE24457.1 - 4.8e-12 45.2 9.5 4.8e-12 45.2 6.6 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EPE24457.1 - 5.4e-08 31.5 29.1 1.6e-07 29.9 20.2 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE24459.1 - 3.6e-126 421.3 27.6 4.2e-126 421.1 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE24459.1 - 3.3e-19 68.8 44.8 3.9e-14 52.1 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3165 PF11364.3 EPE24459.1 - 1.1 9.4 7.6 0.2 11.7 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3165) Glyco_hydro_61 PF03443.9 EPE24460.1 - 8.2e-61 205.5 1.2 1.1e-60 205.2 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CorA PF01544.13 EPE24461.1 - 6.4e-10 38.5 1.4 3.8e-09 35.9 0.9 2.3 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Fasciclin PF02469.17 EPE24462.1 - 0.0046 16.9 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain DUF1020 PF06255.8 EPE24462.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1020) Longin PF13774.1 EPE24463.1 - 8.5e-16 57.2 0.0 1.5e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EPE24463.1 - 2.8e-14 52.4 0.5 4.2e-14 51.8 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 EPE24463.1 - 0.068 12.9 0.5 0.13 12.0 0.4 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 TPR_14 PF13428.1 EPE24464.1 - 0.038 14.6 0.0 0.13 12.9 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPE24466.1 - 0.0057 17.1 0.0 9.8 7.1 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPE24466.1 - 0.031 14.7 0.0 15 6.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPE24466.1 - 0.069 12.7 0.0 2.6 7.7 0.0 2.8 2 0 0 2 2 2 0 TPR repeat Pyridoxal_deC PF00282.14 EPE24467.1 - 1.9e-118 395.1 0.0 2.3e-118 394.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 EPE24467.1 - 0.017 14.1 0.0 0.05 12.5 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II PAH PF02671.16 EPE24467.1 - 0.023 14.2 0.3 5.9 6.5 0.1 2.6 2 0 0 2 2 2 0 Paired amphipathic helix repeat SMC_Nse1 PF07574.8 EPE24468.1 - 1.3e-28 100.0 0.2 2e-28 99.3 0.2 1.3 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex DUF427 PF04248.7 EPE24468.1 - 9.1e-21 73.3 1.3 2e-20 72.2 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF427) zf-RING-like PF08746.6 EPE24468.1 - 9.5e-11 41.5 10.9 1.8e-10 40.6 7.6 1.5 1 0 0 1 1 1 1 RING-like domain DUF1033 PF06279.6 EPE24468.1 - 0.018 14.8 0.6 0.04 13.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Phage_int_SAM_4 PF13495.1 EPE24468.1 - 0.029 14.7 0.4 0.15 12.4 0.0 2.3 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Ceramidase_alk PF04734.8 EPE24469.1 - 4.3e-273 907.2 0.2 4.9e-273 907.0 0.1 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Toxin_29 PF08116.6 EPE24469.1 - 5.6 6.8 5.6 16 5.4 3.8 1.8 1 1 0 1 1 1 0 PhTx neurotoxin family DUF383 PF04063.9 EPE24470.1 - 3.3e-74 248.5 1.8 5.3e-74 247.9 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EPE24470.1 - 6.5e-23 80.0 3.3 2.6e-22 78.1 2.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DED PF01335.16 EPE24470.1 - 0.066 13.3 1.1 4.7 7.4 0.1 2.9 2 1 0 2 2 2 0 Death effector domain FMN_dh PF01070.13 EPE24471.1 - 8.3e-122 406.4 0.1 1e-121 406.1 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EPE24471.1 - 5.5e-23 80.5 0.0 1.1e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EPE24471.1 - 1.2e-07 30.9 0.0 2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EPE24471.1 - 0.00082 18.3 0.0 0.0017 17.2 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EPE24471.1 - 0.0047 16.1 0.0 0.0074 15.4 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EPE24471.1 - 0.012 14.9 0.8 0.93 8.7 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein DUF2348 PF09807.4 EPE24472.1 - 1.2e-06 27.8 0.9 2.5e-06 26.7 0.5 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Elong_Iki1 PF10483.4 EPE24472.1 - 0.00063 19.2 1.8 0.0014 18.0 1.3 1.5 1 1 0 1 1 1 1 Elongator subunit Iki1 DnaB_C PF03796.10 EPE24472.1 - 0.0037 16.1 0.3 0.0053 15.6 0.2 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Ribosomal_L37e PF01907.14 EPE24473.1 - 2.4e-14 52.8 0.9 5e-14 51.8 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L37e IncA PF04156.9 EPE24475.1 - 8.2e-05 22.2 17.0 0.022 14.3 5.3 2.3 2 0 0 2 2 2 2 IncA protein BLOC1_2 PF10046.4 EPE24475.1 - 0.0015 18.6 2.5 0.0015 18.6 1.7 2.7 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin PF02996.12 EPE24475.1 - 0.011 15.3 2.6 0.011 15.3 1.8 3.4 2 1 2 4 4 4 0 Prefoldin subunit AAA_13 PF13166.1 EPE24475.1 - 0.051 12.0 3.0 0.067 11.6 2.1 1.2 1 0 0 1 1 1 0 AAA domain FliD_N PF02465.13 EPE24475.1 - 0.097 13.0 2.3 0.15 12.4 0.4 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Adeno_IVa2 PF02456.10 EPE24475.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Cob_adeno_trans PF01923.13 EPE24475.1 - 1.8 8.3 6.3 0.38 10.5 0.4 2.3 2 1 1 3 3 3 0 Cobalamin adenosyltransferase IL2 PF00715.12 EPE24475.1 - 2.2 7.9 7.7 2.5 7.8 0.7 2.4 1 1 1 2 2 2 0 Interleukin 2 Phage_GP20 PF06810.6 EPE24475.1 - 2.5 7.5 13.5 1.1 8.7 3.1 3.0 2 1 0 3 3 3 0 Phage minor structural protein GP20 GvpK PF05121.7 EPE24475.1 - 2.7 7.8 11.7 0.19 11.5 2.2 3.1 2 1 2 4 4 4 0 Gas vesicle protein K FlaC_arch PF05377.6 EPE24475.1 - 3.6 7.5 7.5 5.1 7.0 0.4 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.17 EPE24475.1 - 3.9 7.5 10.3 1.5 8.8 2.0 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mod_r PF07200.8 EPE24475.1 - 4.8 7.0 19.4 0.74 9.7 6.0 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.6 EPE24475.1 - 6.6 5.2 14.6 2.1 6.9 4.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FAD_binding_4 PF01565.18 EPE24478.1 - 2.6e-17 62.5 0.0 4.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF718 PF05336.8 EPE24479.1 - 2.7e-35 120.3 0.7 3.3e-35 120.0 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF718) DUF2704 PF10866.3 EPE24479.1 - 0.089 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) Baculo_LEF-11 PF06385.7 EPE24479.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Baculovirus LEF-11 protein Thioredoxin PF00085.15 EPE24480.1 - 3.6e-07 29.8 0.0 5.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EPE24480.1 - 0.066 13.4 0.1 0.82 9.8 0.1 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain MFS_1 PF07690.11 EPE24482.1 - 9.9e-35 119.8 35.5 2.3e-25 89.0 10.4 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE24482.1 - 1e-16 60.6 0.1 1e-16 60.6 0.0 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Phtf-FEM1B_bdg PF12129.3 EPE24482.1 - 0.11 11.8 0.8 0.24 10.7 0.5 1.5 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor ADH_zinc_N PF00107.21 EPE24484.1 - 3e-30 104.4 0.3 5.7e-30 103.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE24484.1 - 8.3e-13 49.3 0.0 2e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EPE24484.1 - 3.9e-05 23.3 0.2 6.2e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N PF08240.7 EPE24484.1 - 9.6e-05 22.1 0.0 0.0003 20.5 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EPE24484.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EPE24484.1 - 0.022 13.9 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CMAS PF02353.15 EPE24484.1 - 0.062 12.3 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Amidohydro_1 PF01979.15 EPE24485.1 - 4.5e-40 138.3 0.0 6e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EPE24485.1 - 5.1e-07 29.2 0.9 0.0002 20.7 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EPE24485.1 - 9.2e-06 25.3 0.0 2.9e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EPE24485.1 - 0.00011 22.2 0.0 0.097 12.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase cNMP_binding PF00027.24 EPE24486.1 - 1.8e-41 139.8 0.0 1.1e-21 76.4 0.0 4.7 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EPE24486.1 - 2.2e-17 63.6 7.0 7.1e-17 62.0 3.4 2.8 2 1 0 2 2 2 1 Patatin-like phospholipase EIF_2_alpha PF07541.7 EPE24487.1 - 5.4e-38 129.2 0.0 1.1e-37 128.1 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EPE24487.1 - 3.4e-13 49.4 0.7 9.6e-13 48.0 0.5 1.8 1 0 0 1 1 1 1 S1 RNA binding domain Peptidase_S26 PF10502.4 EPE24488.1 - 0.0002 20.9 0.0 0.012 15.0 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EPE24488.1 - 0.0023 17.5 0.0 0.013 15.1 0.0 2.1 2 1 0 2 2 2 1 Peptidase S24-like Mito_carr PF00153.22 EPE24489.1 - 9.7e-63 207.9 1.7 1.3e-20 72.8 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein PPR_2 PF13041.1 EPE24490.1 - 0.00044 20.1 0.0 3.4 7.7 0.0 4.3 4 0 0 4 4 4 2 PPR repeat family NCA2 PF08637.5 EPE24491.1 - 8.5e-89 297.2 0.0 1.9e-88 296.1 0.0 1.6 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ras PF00071.17 EPE24492.1 - 6.5e-66 220.6 0.1 8.1e-66 220.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE24492.1 - 1.4e-19 70.7 0.0 2.2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE24492.1 - 4e-13 48.9 0.1 5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPE24492.1 - 2.6e-06 27.0 0.1 4.6e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPE24492.1 - 5.8e-06 25.6 0.0 6.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPE24492.1 - 0.0038 17.1 0.0 0.0065 16.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE24492.1 - 0.078 12.2 0.0 0.41 9.9 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EPE24492.1 - 0.084 12.4 0.0 0.29 10.6 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EPE24492.1 - 0.088 11.9 0.0 0.23 10.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPE24492.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 EPE24494.1 - 2.8e-54 182.8 0.0 1.3e-37 128.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE24494.1 - 1.3e-07 31.8 2.5 0.026 14.5 0.0 4.3 2 2 1 4 4 4 1 AAA ATPase domain AAA_5 PF07728.9 EPE24494.1 - 1.6e-05 24.6 0.2 0.014 15.1 0.0 3.6 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EPE24494.1 - 1.8e-05 23.9 0.0 0.0022 17.0 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EPE24494.1 - 3.3e-05 23.9 0.0 0.0032 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EPE24494.1 - 7.1e-05 22.8 0.0 0.38 10.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.17 EPE24494.1 - 0.00014 21.9 0.0 0.38 10.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 EPE24494.1 - 0.00022 20.6 5.5 6 6.2 0.0 4.4 2 2 2 4 4 4 1 AAA domain AAA_19 PF13245.1 EPE24494.1 - 0.00055 19.6 0.7 0.098 12.4 0.0 3.0 2 1 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 EPE24494.1 - 0.00087 18.7 0.0 1.5 8.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.1 EPE24494.1 - 0.00097 19.2 5.0 3.6 7.7 0.0 4.4 3 2 1 4 4 3 1 AAA domain AAA_14 PF13173.1 EPE24494.1 - 0.0015 18.3 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EPE24494.1 - 0.0031 17.4 0.1 0.057 13.3 0.0 2.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EPE24494.1 - 0.0074 15.4 0.2 0.19 10.8 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EPE24494.1 - 0.017 14.0 0.0 0.075 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EPE24494.1 - 0.028 13.8 0.4 5.8 6.3 0.0 3.4 3 2 0 3 3 2 0 Sigma-54 interaction domain AAA_33 PF13671.1 EPE24494.1 - 0.045 13.6 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EPE24494.1 - 0.064 12.9 3.2 0.94 9.1 0.2 3.4 3 1 1 4 4 4 0 NACHT domain Rad17 PF03215.10 EPE24494.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KaiC PF06745.8 EPE24494.1 - 0.12 11.4 0.1 4.2 6.4 0.0 2.5 2 0 0 2 2 2 0 KaiC GFRP PF06399.8 EPE24494.1 - 0.14 11.7 0.0 0.46 10.1 0.0 1.8 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Glycos_transf_2 PF00535.21 EPE24495.1 - 1.7e-22 79.9 0.0 2.6e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EPE24495.1 - 5.8e-08 32.8 0.2 4e-05 23.5 0.0 2.7 2 1 1 3 3 3 2 Glycosyltransferase like family 2 LrgB PF04172.11 EPE24495.1 - 0.084 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 LrgB-like family SMK-1 PF04802.10 EPE24496.1 - 1.6e-73 246.3 0.4 3.5e-73 245.2 0.3 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 CMV_1a PF12467.3 EPE24497.1 - 0.99 9.7 5.3 2.2 8.6 3.7 1.5 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family M-inducer_phosp PF06617.8 EPE24497.1 - 3 6.8 8.3 0.11 11.5 0.5 2.2 3 0 0 3 3 3 0 M-phase inducer phosphatase SE PF08491.5 EPE24498.1 - 1.8e-97 325.5 0.0 2.4e-97 325.0 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EPE24498.1 - 1.7e-09 37.0 0.1 6.5e-09 35.1 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPE24498.1 - 1.5e-08 34.1 0.6 2.3e-05 23.6 0.1 2.7 2 1 0 2 2 2 2 FAD binding domain GIDA PF01134.17 EPE24498.1 - 1.8e-05 23.7 0.2 0.00046 19.1 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EPE24498.1 - 2.1e-05 24.4 0.5 4.5e-05 23.3 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE24498.1 - 4e-05 22.6 0.7 5.9e-05 22.0 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EPE24498.1 - 0.00014 21.0 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EPE24498.1 - 0.00021 20.5 0.2 0.00029 20.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPE24498.1 - 0.00027 20.8 0.1 0.0005 20.0 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE24498.1 - 0.0012 17.9 0.2 0.018 13.9 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EPE24498.1 - 0.0031 17.8 0.2 0.0068 16.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EPE24498.1 - 0.007 16.0 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EPE24498.1 - 0.0086 15.5 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EPE24498.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 EPE24498.1 - 0.017 13.5 0.2 0.029 12.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 EPE24498.1 - 0.05 13.6 0.1 0.089 12.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EPE24498.1 - 0.071 11.7 0.2 0.19 10.3 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.15 EPE24498.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EPE24498.1 - 0.075 12.8 0.3 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 ThiF family Pterin_4a PF01329.14 EPE24499.1 - 4.3e-27 93.6 0.0 5.7e-27 93.3 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase FA_hydroxylase PF04116.8 EPE24500.1 - 6.2e-17 62.0 19.5 6.2e-17 62.0 13.5 2.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Zn_clus PF00172.13 EPE24501.1 - 0.0063 16.4 3.1 0.0063 16.4 2.2 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Calici_PP_N PF08405.6 EPE24502.1 - 0.099 11.4 0.2 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal Lustrin_cystein PF14625.1 EPE24503.1 - 2.9 8.0 17.7 19 5.4 0.6 4.7 4 0 0 4 4 4 0 Lustrin, cysteine-rich repeated domain adh_short PF00106.20 EPE24504.1 - 1.5e-26 93.3 0.1 2.8e-26 92.4 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE24504.1 - 2.7e-10 40.4 0.0 4.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE24504.1 - 4.5e-08 32.9 0.9 2.1e-07 30.7 0.6 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE24504.1 - 0.0067 15.8 0.0 0.0092 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE24504.1 - 0.041 13.8 0.1 0.074 13.0 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EPE24504.1 - 0.075 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HAD_2 PF13419.1 EPE24506.1 - 7.3e-29 101.2 0.0 8.8e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPE24506.1 - 0.088 13.2 0.0 0.24 11.8 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase SH3_9 PF14604.1 EPE24507.1 - 1.6e-17 62.7 1.2 1.5e-12 46.9 0.4 2.9 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EPE24507.1 - 2.9e-08 33.0 0.9 4.3e-05 22.9 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EPE24507.1 - 0.07 12.5 2.8 0.11 11.9 0.8 2.1 2 0 0 2 2 2 0 SH3 domain zf-C2H2_4 PF13894.1 EPE24508.1 - 0.00016 21.7 34.9 0.044 14.1 0.0 7.0 7 0 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.2 EPE24508.1 - 0.0016 18.6 2.6 0.12 12.6 0.3 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type NAD_binding_10 PF13460.1 EPE24510.1 - 3.8e-20 72.6 0.0 4.5e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE24510.1 - 0.0051 16.2 0.0 0.016 14.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPE24510.1 - 0.0061 15.8 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Zn_clus PF00172.13 EPE24511.1 - 7.1e-07 29.0 7.9 7.1e-07 29.0 5.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.1 EPE24512.1 - 3.1e-15 56.1 0.0 4.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPE24512.1 - 8.5e-15 54.6 0.0 1.5e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPE24512.1 - 5.3e-11 42.3 0.0 9.1e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPE24512.1 - 5.4e-11 42.3 0.0 9.6e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPE24512.1 - 4.1e-08 32.9 0.1 6.6e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PT PF04886.7 EPE24513.1 - 0.019 14.2 6.7 0.019 14.2 4.7 5.6 5 0 0 5 5 5 0 PT repeat PAT1 PF09770.4 EPE24513.1 - 5.7 5.0 8.4 6.6 4.8 5.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sulfate_transp PF00916.15 EPE24514.1 - 7.8e-53 179.2 2.1 7.8e-53 179.2 1.5 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EPE24514.1 - 7.7e-30 102.4 3.3 2.6e-29 100.6 2.3 2.0 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EPE24514.1 - 3.4e-14 52.2 0.0 6.5e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EPE24514.1 - 0.03 14.3 0.0 0.08 12.9 0.0 1.8 1 1 0 1 1 1 0 STAS domain DUF2892 PF11127.3 EPE24514.1 - 8.1 6.3 8.2 0.98 9.2 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2892) Glyco_hydro_61 PF03443.9 EPE24515.1 - 1.4e-67 227.7 0.7 1.6e-67 227.5 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Sugar_tr PF00083.19 EPE24516.1 - 1.9e-119 399.2 28.7 2.1e-119 399.0 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE24516.1 - 9.6e-23 80.4 44.7 6.3e-19 67.9 26.3 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE24516.1 - 6.6e-08 31.3 25.6 7.4e-06 24.6 5.6 3.2 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EPE24516.1 - 0.00034 18.9 3.0 0.00034 18.9 2.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EPE24516.1 - 0.0015 17.3 0.9 0.0015 17.3 0.6 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF791) Mitofilin PF09731.4 EPE24516.1 - 0.19 10.3 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MFS_1_like PF12832.2 EPE24516.1 - 7.8 6.3 17.2 0.17 11.6 0.2 4.0 4 1 0 4 4 4 0 MFS_1 like family GATA PF00320.22 EPE24518.1 - 5.8e-31 105.5 16.8 3.8e-17 61.3 2.3 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EPE24518.1 - 4.5e-06 25.8 1.5 0.016 14.4 0.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EPE24518.1 - 0.0067 15.5 8.5 0.29 10.3 0.4 3.0 2 1 0 2 2 2 2 zinc-ribbon domain HypA PF01155.14 EPE24518.1 - 0.0098 15.5 1.8 0.49 10.1 0.0 2.4 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EPE24518.1 - 0.027 14.4 1.6 3.7 7.5 0.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain RRN7 PF11781.3 EPE24518.1 - 0.036 13.5 5.3 0.73 9.3 0.3 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 EPE24518.1 - 0.072 12.9 15.0 0.17 11.7 0.4 3.4 1 1 2 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.12 EPE24518.1 - 0.21 11.2 3.8 4.4 6.9 0.4 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.7 EPE24518.1 - 0.23 11.2 3.1 6.7 6.5 0.1 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn_Tnp_IS1595 PF12760.2 EPE24518.1 - 0.35 10.7 6.8 0.85 9.4 0.6 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 EPE24518.1 - 0.66 9.5 7.9 0.18 11.4 0.4 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_3 PF13878.1 EPE24518.1 - 0.81 9.3 8.8 6 6.5 0.3 4.3 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO zinc_ribbon_2 PF13240.1 EPE24518.1 - 7.8 6.1 9.8 6.3 6.4 0.0 3.5 4 0 0 4 4 4 0 zinc-ribbon domain CorA PF01544.13 EPE24519.1 - 0.0011 18.0 0.7 0.0018 17.3 0.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein OSCP PF00213.13 EPE24519.1 - 0.013 15.3 1.7 0.026 14.3 0.8 1.7 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit RNase_P_p30 PF01876.11 EPE24521.1 - 6.8e-45 151.9 0.0 9.5e-45 151.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 TFIIS_M PF07500.9 EPE24522.1 - 2.8e-24 85.3 0.9 4.2e-24 84.8 0.1 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EPE24522.1 - 7.4e-18 63.9 6.1 1.2e-17 63.2 4.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EPE24522.1 - 3e-12 45.8 0.6 6.3e-12 44.8 0.4 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Hus1 PF04005.7 EPE24522.1 - 0.075 11.9 2.5 0.6 9.0 0.1 2.1 2 0 0 2 2 2 0 Hus1-like protein S_tail_recep_bd PF14928.1 EPE24522.1 - 0.087 13.0 0.4 0.24 11.6 0.1 1.8 2 0 0 2 2 2 0 Short tail fibre protein receptor-binding domain PALP PF00291.20 EPE24523.1 - 3.2e-54 184.2 0.7 4e-54 183.9 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 EPE24524.1 - 5.8e-39 134.0 0.0 1e-38 133.2 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 EPE24524.1 - 0.032 13.1 0.0 0.076 11.9 0.0 1.5 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase HMG-CoA_red PF00368.13 EPE24525.1 - 2.1e-159 530.1 3.8 3e-159 529.6 2.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EPE24525.1 - 2.5e-47 160.3 0.1 5.9e-47 159.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EPE24525.1 - 2.4e-14 53.0 6.2 8.5e-13 48.0 4.3 2.4 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EPE24525.1 - 2.2e-07 29.2 4.7 2.2e-07 29.2 3.3 1.6 2 1 0 2 2 2 1 Patched family Lig_chan PF00060.21 EPE24525.1 - 0.36 10.5 3.7 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel Isochorismatase PF00857.15 EPE24526.1 - 1.7e-24 86.7 0.0 4.3e-24 85.3 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family SH3_1 PF00018.23 EPE24527.1 - 1.6e-08 33.7 0.0 3.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPE24527.1 - 5.6e-08 32.2 0.1 1.2e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPE24527.1 - 5.7e-05 22.5 0.0 0.00014 21.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain NMU PF02070.10 EPE24527.1 - 0.077 12.5 0.1 0.35 10.4 0.1 2.2 1 0 0 1 1 1 0 Neuromedin U FoP_duplication PF13865.1 EPE24527.1 - 0.095 13.1 3.0 0.58 10.6 2.1 2.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ssu72 PF04722.8 EPE24528.1 - 1.8e-86 288.4 0.0 2e-86 288.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.6 EPE24529.1 - 1.2e-23 82.0 3.9 1.9e-14 52.7 0.5 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF3573 PF12097.3 EPE24529.1 - 0.24 9.9 1.3 0.68 8.4 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) OmpH PF03938.9 EPE24529.1 - 0.92 9.4 32.8 0.3 11.0 0.2 3.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 EPE24529.1 - 5.1 6.0 33.8 0.51 9.3 14.0 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 Acetyltransf_1 PF00583.19 EPE24530.1 - 1.5e-11 44.1 0.0 2.2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE24530.1 - 5.1e-07 29.8 0.0 6.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE24530.1 - 8.9e-06 25.3 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EPE24530.1 - 1e-05 25.7 0.0 1.3e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPE24530.1 - 2e-05 24.5 0.0 4.6e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPE24530.1 - 2.9e-05 24.1 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPE24530.1 - 0.0097 15.7 0.0 0.021 14.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3662 PF12401.3 EPE24530.1 - 0.021 14.9 0.0 0.31 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2662) Acetyltransf_CG PF14542.1 EPE24530.1 - 0.033 14.0 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FMN_bind_2 PF04299.7 EPE24531.1 - 9.9e-47 158.5 0.0 1.3e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain DUF3854 PF12965.2 EPE24531.1 - 0.025 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Transp_cyt_pur PF02133.10 EPE24532.1 - 1.4e-44 152.3 35.6 1.8e-44 152.0 24.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Lactamase_B PF00753.22 EPE24533.1 - 2.2e-14 53.5 0.8 4.3e-14 52.6 0.5 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPE24533.1 - 6.9e-07 29.0 0.1 8.7e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HET PF06985.6 EPE24535.1 - 7.9e-22 77.9 0.0 2.1e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pro_isomerase PF00160.16 EPE24536.1 - 1.5e-47 161.6 0.4 1.7e-47 161.5 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-RING_2 PF13639.1 EPE24537.1 - 1.3e-13 50.4 6.1 2e-13 49.8 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPE24537.1 - 6e-08 32.2 3.5 9.8e-08 31.5 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE24537.1 - 1.1e-07 31.8 1.3 2.1e-07 30.9 0.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPE24537.1 - 3.9e-06 26.4 3.4 6.1e-06 25.8 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPE24537.1 - 2.5e-05 24.2 5.0 4e-05 23.5 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE24537.1 - 0.00013 21.5 1.8 0.00019 21.0 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPE24537.1 - 0.0025 17.6 2.8 0.0067 16.2 1.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EPE24537.1 - 0.0059 16.1 6.2 0.01 15.3 4.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EPE24537.1 - 0.071 13.0 3.0 0.2 11.6 2.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EPE24537.1 - 0.1 12.2 5.1 0.18 11.5 3.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 EPE24537.1 - 0.11 12.2 0.5 0.24 11.1 0.2 1.8 1 1 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 EPE24537.1 - 0.17 11.9 5.4 0.3 11.1 3.7 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EPE24537.1 - 0.21 11.4 4.5 0.42 10.5 3.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 EPE24537.1 - 5.5 6.7 7.4 0.54 10.0 0.7 2.0 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3752 PF12572.3 EPE24538.1 - 2.2e-34 118.7 11.1 3.9e-34 117.9 7.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Vps8 PF12816.2 EPE24539.1 - 3.6e-73 245.0 0.1 8.3e-73 243.8 0.1 1.7 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EPE24539.1 - 0.00025 20.6 0.0 0.33 10.5 0.0 2.8 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_5 PF14634.1 EPE24539.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EPE24539.1 - 0.017 14.9 0.0 0.056 13.2 0.0 1.8 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.2 EPE24539.1 - 0.25 11.4 0.0 0.57 10.3 0.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPE24539.1 - 0.3 11.1 0.0 0.78 9.8 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RTA1 PF04479.8 EPE24542.1 - 3.5e-46 157.5 0.5 4.5e-46 157.1 0.4 1.1 1 0 0 1 1 1 1 RTA1 like protein ADH_zinc_N PF00107.21 EPE24543.1 - 1.5e-09 37.4 0.1 2.6e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE24543.1 - 4e-07 29.7 0.0 7.1e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SspN PF08177.6 EPE24543.1 - 0.015 14.9 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Small acid-soluble spore protein N family PALP PF00291.20 EPE24543.1 - 0.022 13.9 0.5 0.055 12.6 0.3 1.5 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF2374 PF09574.5 EPE24543.1 - 0.055 13.1 1.0 0.13 11.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) Eno-Rase_NADH_b PF12242.3 EPE24543.1 - 0.12 12.1 1.1 3.1 7.6 0.4 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EPE24543.1 - 0.18 11.7 1.8 0.53 10.2 1.3 1.7 1 1 1 2 2 2 0 NADH(P)-binding F-box PF00646.28 EPE24544.1 - 0.061 12.9 0.5 0.16 11.6 0.3 1.7 1 0 0 1 1 1 0 F-box domain ESR1_C PF12743.2 EPE24545.1 - 0.83 9.2 3.7 12 5.5 0.2 2.5 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal ADH_zinc_N PF00107.21 EPE24546.1 - 4.3e-24 84.5 0.1 6.5e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE24546.1 - 5.1e-08 33.8 0.0 1e-07 32.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RRM_1 PF00076.17 EPE24548.1 - 9.1e-06 25.2 0.0 0.0027 17.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE24548.1 - 0.00046 19.9 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE24548.1 - 0.0016 18.3 0.0 0.038 13.9 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_S8 PF00082.17 EPE24550.1 - 1.2e-55 188.6 0.8 1.7e-55 188.1 0.6 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EPE24550.1 - 3.3e-25 87.6 0.4 6.4e-25 86.7 0.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Glyco_hydro_3 PF00933.16 EPE24551.1 - 2.6e-83 279.4 0.0 3.8e-83 278.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE24551.1 - 8.7e-75 251.1 0.6 1.1e-72 244.2 0.0 2.5 3 0 0 3 3 3 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE24551.1 - 4.8e-22 77.6 0.0 9.6e-22 76.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EPE24551.1 - 1.3e-12 47.5 0.7 1.9e-12 47.0 0.0 1.6 2 0 0 2 2 2 1 PA14 domain DUF202 PF02656.10 EPE24553.1 - 2.8e-18 65.8 3.7 4.2e-18 65.3 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Baculo_11_kDa PF06143.6 EPE24553.1 - 0.15 11.4 0.8 0.25 10.7 0.5 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family CcmD PF04995.9 EPE24553.1 - 7.7 6.3 7.3 1.6 8.4 1.8 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Cation_efflux PF01545.16 EPE24554.1 - 3.2e-75 252.8 8.2 1.3e-74 250.8 5.7 1.8 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 EPE24554.1 - 2.3e-05 23.5 0.6 2.3e-05 23.5 0.4 2.5 1 1 0 2 2 2 1 ZIP Zinc transporter NicO PF03824.11 EPE24554.1 - 0.00075 18.8 0.3 0.00075 18.8 0.2 3.0 3 1 0 3 3 3 1 High-affinity nickel-transport protein Squash PF00299.13 EPE24554.1 - 6.5 6.6 13.5 12 5.7 9.4 1.4 1 0 0 1 1 1 0 Squash family serine protease inhibitor Myosin_head PF00063.16 EPE24555.1 - 7.2e-230 764.6 1.3 1.1e-229 764.0 0.9 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EPE24555.1 - 4.7e-42 143.5 0.0 9.5e-42 142.5 0.0 1.6 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EPE24555.1 - 8.2e-11 41.1 0.1 1.6e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPE24555.1 - 1.1e-07 31.2 0.0 2.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EPE24555.1 - 1.2e-07 31.2 0.1 3.5e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EPE24555.1 - 0.0039 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Hpr_kinase_C PF07475.7 EPE24555.1 - 0.0055 16.0 0.3 1.6 8.0 0.0 2.4 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain IQ PF00612.22 EPE24555.1 - 0.014 14.9 7.7 0.51 10.1 0.6 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif Zeta_toxin PF06414.7 EPE24555.1 - 0.024 13.7 0.0 0.062 12.3 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EPE24555.1 - 0.026 15.3 0.0 0.077 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPE24555.1 - 0.059 13.5 0.3 0.46 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase eIF-1a PF01176.14 EPE24555.1 - 0.071 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 AAA_18 PF13238.1 EPE24555.1 - 0.072 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPE24555.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 EPE24555.1 - 0.15 11.5 0.3 0.85 9.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain SET PF00856.23 EPE24556.1 - 1.4e-11 44.9 0.4 2.5e-10 40.8 0.3 2.5 2 1 0 2 2 2 1 SET domain FAD_binding_8 PF08022.7 EPE24558.1 - 1.9e-22 79.0 0.0 3.8e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EPE24558.1 - 3.4e-22 79.0 0.0 5.6e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPE24558.1 - 7.1e-17 61.6 6.3 1.6e-16 60.5 4.3 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EPE24558.1 - 5.3e-06 26.4 0.0 1.6e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain ubiquitin PF00240.18 EPE24559.1 - 1.3e-16 59.7 0.0 2.2e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EPE24559.1 - 2.9e-07 30.1 0.0 2.9e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.1 EPE24559.1 - 0.0013 18.6 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 EPE24559.1 - 0.0032 17.1 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ADH_zinc_N PF00107.21 EPE24560.1 - 2.3e-34 117.7 0.1 3.8e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE24560.1 - 4e-09 37.4 0.0 1e-08 36.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE24560.1 - 2.9e-07 30.2 0.0 2.6e-06 27.1 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EPE24560.1 - 0.02 14.9 0.1 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.1 EPE24560.1 - 0.046 13.7 0.2 0.081 12.9 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 EPE24560.1 - 0.061 12.8 2.0 0.3 10.6 1.3 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SprT-like PF10263.4 EPE24562.1 - 5.3e-11 42.4 0.2 7.9e-11 41.8 0.2 1.2 1 0 0 1 1 1 1 SprT-like family F-box-like PF12937.2 EPE24564.1 - 1.2e-07 31.3 0.8 2.4e-07 30.3 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE24564.1 - 5.6e-05 22.6 0.2 0.00012 21.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain Imm15 PF15590.1 EPE24565.1 - 0.011 14.8 0.0 0.6 9.2 0.0 2.7 2 0 0 2 2 2 0 Immunity protein 15 DUF1713 PF08213.6 EPE24566.1 - 1.2e-13 50.3 20.0 1.2e-13 50.3 13.8 1.9 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Asp PF00026.18 EPE24567.1 - 2.6e-46 158.3 0.0 4.3e-46 157.6 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EPE24567.1 - 1.2e-06 28.9 0.4 0.00078 19.8 0.1 3.4 2 2 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.1 EPE24567.1 - 0.00018 21.4 0.2 0.00055 19.9 0.1 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EPE24567.1 - 0.0016 18.2 0.1 0.012 15.3 0.1 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 EPE24567.1 - 0.0038 16.7 0.2 0.016 14.7 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal RVP PF00077.15 EPE24567.1 - 0.031 14.1 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease UDPGP PF01704.13 EPE24570.1 - 4.1e-55 186.9 0.0 5.6e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Fer4_20 PF14691.1 EPE24570.1 - 0.031 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Spc7 PF08317.6 EPE24570.1 - 0.061 11.9 0.0 0.78 8.3 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein NTP_transf_3 PF12804.2 EPE24570.1 - 0.085 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain UQ_con PF00179.21 EPE24571.1 - 8.1e-49 164.6 0.0 1e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPE24571.1 - 3.4e-06 26.8 0.0 4.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPE24571.1 - 0.00031 20.6 0.3 0.00052 19.8 0.2 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EPE24571.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.20 EPE24572.1 - 2e-60 204.1 0.0 2.7e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE24572.1 - 6.8e-28 97.4 0.0 9.6e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE24572.1 - 2.8e-08 33.0 0.0 4.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPE24572.1 - 0.0024 17.6 0.0 0.88 9.2 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EPE24572.1 - 0.039 13.0 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UDG PF03167.14 EPE24573.1 - 1.3e-17 63.6 0.0 2e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF605 PF04652.11 EPE24573.1 - 0.25 10.7 10.8 0.29 10.5 7.5 1.1 1 0 0 1 1 1 0 Vta1 like Ribosomal_L31e PF01198.14 EPE24574.1 - 8.9e-38 127.8 0.9 1.2e-37 127.4 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e RGS PF00615.14 EPE24575.1 - 3.1e-12 46.6 0.0 5.3e-09 36.1 0.0 2.5 2 1 0 2 2 2 2 Regulator of G protein signaling domain PAP1 PF08601.5 EPE24575.1 - 0.018 14.7 2.6 0.023 14.3 1.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 PCI PF01399.22 EPE24576.1 - 3e-06 27.4 0.0 6e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 PCI domain DivIC PF04977.10 EPE24576.1 - 0.13 11.8 0.2 0.34 10.4 0.1 1.7 1 0 0 1 1 1 0 Septum formation initiator E1-E2_ATPase PF00122.15 EPE24577.1 - 6.1e-55 185.7 4.9 6.2e-54 182.4 0.4 2.6 2 0 0 2 2 2 2 E1-E2 ATPase HMA PF00403.21 EPE24577.1 - 8.7e-47 157.1 0.3 1.8e-11 44.0 0.1 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 EPE24577.1 - 3.6e-46 158.2 1.5 3.6e-46 158.2 1.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPE24577.1 - 5.2e-15 56.1 0.0 1.2e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPE24577.1 - 2.9e-07 30.3 0.6 6.9e-05 22.5 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3133 PF11331.3 EPE24577.1 - 0.0032 16.9 0.9 4.7 6.8 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3133) FAM70 PF14967.1 EPE24577.1 - 0.029 13.5 0.5 6.7 5.8 0.0 3.0 3 0 0 3 3 3 0 FAM70 protein DUF2089 PF09862.4 EPE24577.1 - 0.52 10.1 2.0 34 4.2 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2089) DUF155 PF02582.9 EPE24578.1 - 5e-64 215.4 0.1 9e-64 214.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 bZIP_2 PF07716.10 EPE24578.1 - 0.9 9.4 7.0 1.7 8.5 4.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper p450 PF00067.17 EPE24579.1 - 5.6e-63 213.0 0.0 1e-62 212.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 cNMP_binding PF00027.24 EPE24581.1 - 3.2e-35 119.8 0.0 4.3e-18 64.9 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EPE24581.1 - 1.2e-11 43.4 10.4 1.1 9.5 0.0 8.4 8 0 0 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.1 EPE24581.1 - 1.7e-08 34.0 0.4 0.0024 17.5 0.2 4.9 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EPE24581.1 - 1.5e-06 27.4 8.7 18 5.8 0.0 8.3 6 3 2 8 8 8 2 Leucine Rich Repeat F-box-like PF12937.2 EPE24581.1 - 1.1e-05 25.0 3.9 2.1e-05 24.1 0.2 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EPE24581.1 - 0.00094 18.7 0.6 0.00094 18.7 0.4 3.4 3 0 0 3 3 3 1 F-box domain LRR_7 PF13504.1 EPE24581.1 - 2.2 8.8 17.2 52 4.6 0.0 7.7 10 0 0 10 10 10 0 Leucine rich repeat Cactin_mid PF10312.4 EPE24583.1 - 8.6e-64 214.3 3.4 8.6e-64 214.3 2.4 1.6 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EPE24583.1 - 3.1e-50 168.9 2.0 1.4e-49 166.8 0.9 2.1 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.8 EPE24583.1 - 0.021 14.7 1.7 0.22 11.4 0.2 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF1139 PF06599.6 EPE24583.1 - 0.28 10.2 2.6 0.15 11.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1139) Fork_head PF00250.13 EPE24584.1 - 5.1e-15 55.2 0.1 1.1e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Fork head domain DUF3678 PF12435.3 EPE24584.1 - 0.068 12.7 2.9 0.2 11.2 2.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Glyco_hydro_28 PF00295.12 EPE24585.1 - 1.1e-51 175.7 4.5 2.1e-51 174.8 3.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 XLF PF09302.6 EPE24586.1 - 8.5e-38 129.8 0.5 1.2e-37 129.2 0.3 1.2 1 0 0 1 1 1 1 XLF (XRCC4-like factor) DUF2458 PF10454.4 EPE24587.1 - 0.035 13.9 0.2 0.038 13.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) WD40 PF00400.27 EPE24588.1 - 7.1e-16 57.4 12.5 7.9e-07 28.7 0.8 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EPE24588.1 - 0.002 17.8 0.0 0.2 11.3 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Myb_DNA-binding PF00249.26 EPE24589.1 - 0.0062 16.5 0.5 1.9 8.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPE24589.1 - 0.049 13.7 0.3 0.27 11.3 0.2 2.1 1 1 0 1 1 1 0 Myb-like DNA-binding domain Fungal_trans PF04082.13 EPE24590.1 - 2.4e-06 26.6 0.6 5.5e-06 25.4 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE24590.1 - 4e-06 26.6 9.6 4e-06 26.6 6.7 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FYTT PF07078.6 EPE24590.1 - 0.047 13.0 0.3 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Forty-two-three protein Cellulase PF00150.13 EPE24592.1 - 1.7e-15 56.9 2.2 1.7e-15 56.9 1.5 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Aldedh PF00171.17 EPE24593.1 - 1.2e-140 468.9 0.2 1.4e-140 468.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IBN_N PF03810.14 EPE24594.1 - 2.6e-11 43.2 0.1 5e-10 39.1 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EPE24594.1 - 0.023 14.6 2.5 0.25 11.2 0.1 3.2 2 1 1 3 3 3 0 Exportin 1-like protein Ank_2 PF12796.2 EPE24595.1 - 1.2e-27 96.0 0.2 1.5e-08 34.8 0.0 4.6 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPE24595.1 - 2.2e-17 61.8 3.2 0.0035 17.0 0.0 8.2 7 1 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.1 EPE24595.1 - 1.2e-15 56.0 0.8 0.0033 17.5 0.0 7.7 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 EPE24595.1 - 6.4e-14 52.0 0.1 0.0039 17.6 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE24595.1 - 8.2e-09 35.4 0.2 0.026 14.7 0.0 5.4 4 3 2 6 6 6 2 Ankyrin repeats (many copies) PLC-beta_C PF08703.5 EPE24595.1 - 0.0038 16.9 0.1 0.0064 16.2 0.1 1.3 1 0 0 1 1 1 1 PLC-beta C terminal Shigella_OspC PF06128.6 EPE24595.1 - 0.041 13.3 0.0 2.6 7.4 0.0 2.7 3 0 0 3 3 3 0 Shigella flexneri OspC protein MFS_1 PF07690.11 EPE24596.1 - 3.1e-52 177.4 52.1 6e-52 176.4 36.1 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE24596.1 - 6.7e-24 84.0 21.6 8.3e-24 83.7 15.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE24596.1 - 5.4e-18 64.7 10.5 5.4e-18 64.7 7.3 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EPE24596.1 - 9e-06 24.3 9.1 9e-06 24.3 6.3 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein GCS2 PF04107.8 EPE24596.1 - 1.5 7.8 3.9 11 4.9 1.0 2.2 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) DUF963 PF06131.6 EPE24596.1 - 1.8 7.9 4.7 3.8 6.8 3.3 1.5 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) MFS_1 PF07690.11 EPE24597.1 - 1.1e-46 159.1 41.6 3e-44 151.2 28.0 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE24597.1 - 6.6e-13 48.0 10.2 6.6e-13 48.0 7.1 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EPE24597.1 - 1.8e-08 33.0 5.6 1.8e-08 33.0 3.9 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2140 PF09911.4 EPE24597.1 - 0.028 13.5 0.1 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) HXXEE PF13787.1 EPE24597.1 - 0.19 12.0 14.2 0.63 10.4 1.7 3.3 3 0 0 3 3 3 0 Protein of unknown function with HXXEE motif Zn_clus PF00172.13 EPE24598.1 - 0.0016 18.2 9.2 0.0027 17.5 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 EPE24600.1 - 2.1e-08 33.7 0.1 5.6e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE24600.1 - 4.6e-08 32.7 0.3 1.3e-07 31.3 0.2 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPE24600.1 - 9.6e-08 32.9 0.1 4.8e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EPE24600.1 - 0.047 13.6 0.1 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Paramyx_P_V_C PF03210.8 EPE24601.1 - 0.037 13.9 0.2 0.044 13.6 0.2 1.1 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Zn_clus PF00172.13 EPE24602.1 - 2.6e-09 36.8 5.9 4.2e-09 36.1 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE24602.1 - 1.6e-06 27.1 0.0 2.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pex2_Pex12 PF04757.9 EPE24603.1 - 3e-41 141.3 0.9 4.8e-41 140.6 0.6 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EPE24603.1 - 0.00078 19.2 4.0 0.0016 18.2 2.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPE24603.1 - 0.1 12.3 2.4 0.17 11.6 0.1 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EPE24603.1 - 0.93 9.5 7.8 0.61 10.1 2.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Na_trans_assoc PF06512.8 EPE24603.1 - 1.5 8.7 4.6 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 Sodium ion transport-associated zf-C3HC4_3 PF13920.1 EPE24603.1 - 1.5 8.5 5.2 8.8 6.0 1.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Na_H_Exchanger PF00999.16 EPE24604.1 - 9.2e-54 182.4 24.5 1.3e-53 181.9 17.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PTS_EIIC_2 PF13303.1 EPE24604.1 - 0.0048 15.7 1.1 0.0048 15.7 0.8 2.2 2 1 0 2 2 2 1 Phosphotransferase system, EIIC YIEGIA PF14045.1 EPE24604.1 - 0.089 11.4 0.4 0.14 10.7 0.3 1.3 1 0 0 1 1 1 0 YIEGIA protein DUF3272 PF11676.3 EPE24604.1 - 5.9 6.9 7.7 23 5.1 0.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) FtsX PF02687.16 EPE24604.1 - 9 6.0 24.6 0.41 10.4 2.7 4.3 4 2 0 4 4 4 0 FtsX-like permease family SET PF00856.23 EPE24605.1 - 1.3e-11 45.0 0.3 1.1e-09 38.8 0.2 2.7 1 1 0 1 1 1 1 SET domain HCO3_cotransp PF00955.16 EPE24606.1 - 3.1e-50 171.3 10.5 1.1e-28 100.1 2.1 2.1 1 1 1 2 2 2 2 HCO3- transporter family Peptidase_S49 PF01343.13 EPE24606.1 - 0.26 11.0 0.2 0.46 10.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 PEP_mutase PF13714.1 EPE24607.1 - 3.3e-45 154.1 1.5 3.9e-45 153.9 1.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EPE24607.1 - 1e-20 73.5 0.5 1.3e-20 73.1 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family WLM PF08325.5 EPE24608.1 - 7.8e-54 182.3 0.1 1.8e-53 181.2 0.0 1.6 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EPE24608.1 - 0.0034 16.4 3.4 0.0034 16.4 2.4 3.4 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EPE24608.1 - 0.026 14.3 11.0 0.052 13.3 7.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon DUF45 PF01863.12 EPE24608.1 - 0.027 14.2 3.3 0.06 13.1 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF45 SprT-like PF10263.4 EPE24608.1 - 0.14 11.8 0.0 0.14 11.8 0.0 2.5 2 1 0 2 2 2 0 SprT-like family zf-Sec23_Sec24 PF04810.10 EPE24608.1 - 3.4 7.3 15.7 3.8 7.1 0.2 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger DUF1776 PF08643.5 EPE24609.1 - 1e-101 340.0 0.3 2.3e-101 338.8 0.0 1.6 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Dscam_C PF12355.3 EPE24609.1 - 0.0056 16.9 0.5 0.015 15.5 0.3 1.7 1 0 0 1 1 1 1 Down syndrome cell adhesion molecule C terminal P12 PF12669.2 EPE24609.1 - 0.18 12.0 0.7 0.32 11.2 0.5 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family MSC PF09402.5 EPE24609.1 - 0.21 10.2 0.1 0.35 9.5 0.1 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain zf-CCCH PF00642.19 EPE24610.1 - 8.8e-25 85.8 29.8 8e-07 28.6 0.2 5.2 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPE24610.1 - 0.022 14.7 0.2 0.022 14.7 0.2 6.0 7 0 0 7 7 7 0 Zinc finger C-x8-C-x5-C-x3-H type GRP PF07172.6 EPE24610.1 - 6.8 7.2 19.0 10 6.6 13.2 1.2 1 0 0 1 1 1 0 Glycine rich protein family Glyco_hydro_18 PF00704.23 EPE24611.1 - 4.2e-79 266.4 0.0 4.8e-79 266.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 IBR PF01485.16 EPE24613.1 - 1.5e-11 44.0 36.1 1.8e-06 27.7 4.3 3.4 3 0 0 3 3 3 3 IBR domain Acetyltransf_1 PF00583.19 EPE24614.1 - 1.8e-06 27.8 0.0 4.9e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE24614.1 - 4.7e-05 23.4 0.0 7.9e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE24614.1 - 0.002 18.2 0.0 0.0057 16.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 EPE24615.1 - 2.1e-20 72.6 25.2 2.9e-20 72.2 17.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE24615.1 - 1.9e-05 23.2 22.4 2.3e-05 22.9 15.6 1.0 1 0 0 1 1 1 1 Amino acid permease NfeD PF01957.13 EPE24615.1 - 0.0091 16.1 2.7 0.0091 16.1 1.9 2.3 1 1 1 2 2 2 1 NfeD-like C-terminal, partner-binding GRAM PF02893.15 EPE24616.1 - 2.1e-17 62.4 0.0 3.7e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Acyl_transf_1 PF00698.16 EPE24617.1 - 9.8e-81 271.5 0.0 1.8e-79 267.3 0.0 2.9 4 0 0 4 4 4 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EPE24617.1 - 2.4e-39 133.4 0.0 5.3e-39 132.4 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EPE24617.1 - 1.8e-30 104.4 0.1 4.9e-30 103.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EPE24617.1 - 4.1e-22 78.3 0.0 1.8e-21 76.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EPE24617.1 - 0.00028 20.1 0.6 0.049 12.7 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase PCIF1_WW PF12237.3 EPE24617.1 - 0.088 12.0 0.0 0.25 10.6 0.0 1.7 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain adh_short_C2 PF13561.1 EPE24618.1 - 2e-20 73.6 0.0 9.8e-20 71.3 0.0 2.2 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 EPE24618.1 - 2.5e-20 73.0 0.0 4.8e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EPE24618.1 - 8.7e-18 64.2 0.1 2.5e-17 62.7 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EPE24618.1 - 6.1e-11 42.2 0.2 4.9e-10 39.2 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EPE24618.1 - 5.3e-05 23.2 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE24618.1 - 0.0085 15.7 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 KR domain Tannase PF07519.6 EPE24619.1 - 1.4e-109 366.9 2.9 2e-109 366.4 2.0 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EPE24619.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Gp23 PF07068.6 EPE24619.1 - 0.04 12.4 0.0 0.067 11.7 0.0 1.2 1 0 0 1 1 1 0 Major capsid protein Gp23 HET PF06985.6 EPE24620.1 - 6e-32 110.7 0.2 1e-31 109.9 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Actin PF00022.14 EPE24622.1 - 3e-18 65.4 0.0 1.4e-16 59.9 0.0 2.6 2 1 0 2 2 2 1 Actin MreB_Mbl PF06723.8 EPE24622.1 - 3.1e-08 32.5 0.0 9.3e-05 21.1 0.0 2.9 2 1 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.3 EPE24622.1 - 0.0013 17.6 0.0 0.011 14.6 0.0 2.0 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; PIN_3 PF13470.1 EPE24622.1 - 0.06 14.0 0.3 0.42 11.3 0.0 2.3 2 0 0 2 2 2 0 PIN domain Ras PF00071.17 EPE24624.1 - 6.7e-41 139.3 0.0 1.5e-38 131.7 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EPE24624.1 - 5.4e-16 59.1 0.0 7.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE24624.1 - 1.5e-11 43.8 0.0 2.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPE24624.1 - 0.001 18.2 0.0 0.0016 17.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPE24624.1 - 0.0035 17.2 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPE24624.1 - 0.0073 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EPE24624.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EPE24624.1 - 0.036 13.8 0.0 0.076 12.8 0.0 1.5 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.1 EPE24624.1 - 0.046 13.8 0.0 0.098 12.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EPE24624.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 EPE24624.1 - 0.1 12.1 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EPE24624.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPE24624.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain FAD_binding_2 PF00890.19 EPE24625.1 - 2.3e-84 283.6 0.9 3e-84 283.3 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EPE24625.1 - 1.3e-20 72.9 0.7 1.8e-19 69.3 0.0 2.9 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EPE24625.1 - 1.3e-13 50.6 2.9 8.9e-13 47.8 2.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EPE24625.1 - 8.7e-10 38.2 0.4 3.1e-09 36.4 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE24625.1 - 2.4e-07 30.6 5.7 3e-07 30.3 0.6 3.2 3 1 1 4 4 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE24625.1 - 3.8e-07 30.2 0.0 3.6e-05 23.7 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE24625.1 - 8.2e-06 25.0 2.0 0.011 14.8 0.2 3.3 3 0 0 3 3 3 2 Thi4 family HI0933_like PF03486.9 EPE24625.1 - 0.0001 20.9 4.1 0.0058 15.1 0.2 3.2 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.19 EPE24625.1 - 0.00031 19.9 0.1 0.22 10.5 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.17 EPE24625.1 - 0.00036 19.4 3.2 0.067 12.0 0.4 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EPE24625.1 - 0.00066 18.8 1.1 0.0062 15.6 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EPE24625.1 - 0.013 15.8 2.5 1.4 9.4 0.4 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE24625.1 - 0.023 14.7 1.1 0.094 12.7 0.8 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PAH PF02671.16 EPE24626.1 - 1.3e-49 165.5 0.5 1e-16 60.2 0.4 4.0 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EPE24626.1 - 2.1e-33 114.0 0.9 9e-29 99.2 0.1 3.9 3 0 0 3 3 3 3 Sin3 family co-repressor MTBP_mid PF14919.1 EPE24627.1 - 0.15 10.7 2.2 0.16 10.6 1.6 1.2 1 0 0 1 1 1 0 MDM2-binding Band_3_cyto PF07565.8 EPE24627.1 - 0.16 11.4 3.6 0.2 11.1 2.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2383 PF09537.5 EPE24627.1 - 0.47 10.7 5.1 0.98 9.6 2.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) SAP PF02037.22 EPE24628.1 - 7.4e-05 22.1 0.1 7.4e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 SAP domain DUF4200 PF13863.1 EPE24628.1 - 0.046 13.6 8.0 0.079 12.9 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Adenyl_transf PF04439.7 EPE24628.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Streptomycin adenylyltransferase HET PF06985.6 EPE24630.1 - 0.029 14.5 0.1 0.071 13.2 0.1 1.7 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Peptidase_M16 PF00675.15 EPE24631.1 - 4.8e-56 188.6 0.3 1.7e-55 186.8 0.2 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPE24631.1 - 3.1e-40 137.8 0.1 9.9e-40 136.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain CybS PF05328.7 EPE24632.1 - 3.9e-51 172.1 0.0 5.1e-51 171.7 0.0 1.2 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 EPE24632.1 - 0.12 12.2 0.8 1.5 8.6 0.5 2.1 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pyr_redox_2 PF07992.9 EPE24636.1 - 9.4e-30 103.9 0.0 1.7e-29 103.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE24636.1 - 4.2e-15 55.8 6.2 7.4e-14 51.9 0.9 3.3 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE24636.1 - 2.6e-08 34.1 0.5 0.00012 22.1 0.0 3.1 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE24636.1 - 4.3e-06 25.8 4.2 0.36 9.6 0.1 3.5 3 1 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EPE24636.1 - 2.1e-05 24.6 0.7 0.005 17.0 0.1 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EPE24636.1 - 3.2e-05 23.1 2.7 0.00047 19.3 0.0 2.6 2 1 1 3 3 3 1 Thi4 family NAD_binding_8 PF13450.1 EPE24636.1 - 0.00056 19.8 0.8 0.028 14.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EPE24636.1 - 0.007 16.4 0.6 5.2 7.1 0.1 2.5 2 1 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EPE24636.1 - 0.011 14.8 0.2 0.29 10.1 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPE24636.1 - 0.016 14.2 3.6 4.9 6.0 0.0 3.1 2 1 1 3 3 3 0 FAD binding domain Trp_halogenase PF04820.9 EPE24636.1 - 0.02 13.5 0.7 0.42 9.1 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.19 EPE24636.1 - 0.021 13.7 8.2 0.28 9.9 0.4 3.1 2 1 0 3 3 3 0 FAD binding domain K_oxygenase PF13434.1 EPE24636.1 - 0.021 13.7 0.7 2 7.2 0.0 3.2 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EPE24636.1 - 0.022 13.6 7.4 0.76 8.5 0.2 3.8 3 1 1 4 4 4 0 Glucose inhibited division protein A HI0933_like PF03486.9 EPE24636.1 - 0.049 12.0 1.6 2.9 6.2 0.1 3.2 2 2 1 3 3 3 0 HI0933-like protein PX PF00787.19 EPE24637.1 - 5.5e-21 74.4 0.2 2.3e-20 72.5 0.1 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EPE24637.1 - 3.1e-10 39.7 5.5 8.4e-05 21.9 0.1 2.2 1 1 1 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EPE24637.1 - 2.2e-07 30.6 1.0 4.3e-07 29.6 0.7 1.5 1 1 0 1 1 1 1 BAR domain Reo_sigmaC PF04582.7 EPE24637.1 - 0.0015 17.7 0.1 0.0031 16.7 0.0 1.4 2 0 0 2 2 2 1 Reovirus sigma C capsid protein FlaC_arch PF05377.6 EPE24637.1 - 0.027 14.3 0.1 9.3 6.2 0.0 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EPE24637.1 - 0.2 11.2 4.5 0.22 11.1 0.1 2.2 2 0 0 2 2 2 0 IncA protein DUF4404 PF14357.1 EPE24637.1 - 0.56 10.6 3.1 4 7.9 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3586 PF12131.3 EPE24639.1 - 0.19 11.7 2.1 0.38 10.8 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3586) TSC22 PF01166.13 EPE24640.1 - 0.059 13.3 0.2 0.059 13.3 0.1 4.6 4 0 0 4 4 4 0 TSC-22/dip/bun family AAA_27 PF13514.1 EPE24640.1 - 0.38 8.3 43.0 1.9 6.0 29.0 1.9 1 1 0 1 1 1 0 AAA domain DUF948 PF06103.6 EPE24640.1 - 2.6 7.9 16.8 0.28 11.0 0.3 4.5 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) MFS_1 PF07690.11 EPE24641.1 - 4.7e-33 114.3 21.9 6.1e-33 113.9 15.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ion_trans_2 PF07885.11 EPE24641.1 - 7.6 6.3 15.3 0.044 13.4 1.5 3.3 3 0 0 3 3 3 0 Ion channel GFO_IDH_MocA PF01408.17 EPE24642.1 - 3.2e-17 63.1 0.0 6.5e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPE24642.1 - 4.3e-16 58.7 0.2 1.2e-15 57.3 0.1 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PP_kinase_N PF13089.1 EPE24643.1 - 0.009 16.1 0.3 0.08 13.0 0.0 2.5 2 1 1 3 3 3 1 Polyphosphate kinase N-terminal domain Glutaredoxin2_C PF04399.8 EPE24643.1 - 0.045 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain TLP-20 PF06088.6 EPE24644.1 - 1 8.9 12.1 4 7.0 2.5 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.9 EPE24644.1 - 1.1 7.1 14.5 0.013 13.5 4.9 1.5 2 0 0 2 2 2 0 CDC45-like protein GST_N_3 PF13417.1 EPE24648.1 - 1.2e-13 51.0 0.0 2.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPE24648.1 - 3.5e-11 42.9 0.1 8.2e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPE24648.1 - 8.7e-10 38.4 0.1 1.6e-09 37.6 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPE24648.1 - 2.2e-08 34.1 0.0 4.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EPE24648.1 - 2e-06 28.1 0.1 2.7e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPE24648.1 - 0.00013 21.7 0.1 0.00025 20.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EPE24648.1 - 0.0094 16.3 0.1 1.7 9.0 0.0 2.2 2 0 0 2 2 2 1 MetRS-N binding domain DUF3791 PF12668.2 EPE24648.1 - 0.013 15.0 0.2 0.038 13.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) TPR_12 PF13424.1 EPE24649.1 - 5.5e-26 90.3 27.1 3.6e-08 33.2 1.2 5.7 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_20 PF14561.1 EPE24649.1 - 1.4e-16 60.3 11.8 0.0055 16.7 0.0 7.7 2 2 5 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.1 EPE24649.1 - 2.4e-16 59.0 15.5 0.14 12.1 0.0 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_6 PF13174.1 EPE24649.1 - 2.5e-16 58.9 5.7 0.42 11.1 0.0 8.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPE24649.1 - 5.8e-15 55.3 15.8 0.0081 16.4 0.1 7.2 3 2 3 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPE24649.1 - 8.6e-15 54.9 4.5 0.00059 20.4 0.8 5.7 2 1 4 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 EPE24649.1 - 4.7e-14 52.2 16.7 0.0015 18.5 0.5 5.3 3 2 1 5 5 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EPE24649.1 - 1.2e-13 50.3 8.4 0.75 10.6 0.1 7.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EPE24649.1 - 1.6e-12 46.2 4.6 1.3 8.9 0.1 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPE24649.1 - 2.5e-12 45.6 6.9 2.5 8.2 0.0 8.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EPE24649.1 - 2.1e-11 42.6 13.0 1 9.2 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_4 PF07721.9 EPE24649.1 - 9.1e-11 41.1 12.9 0.08 13.4 0.3 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPE24649.1 - 3.3e-10 39.3 3.6 2.4 8.5 0.0 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPE24649.1 - 2.9e-09 36.4 8.4 0.096 12.3 0.1 5.4 1 1 7 8 8 8 5 TPR repeat NB-ARC PF00931.17 EPE24649.1 - 1.9e-08 33.5 0.0 3.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 EPE24649.1 - 5.9e-08 31.9 8.5 2.5 7.8 0.0 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat PPR PF01535.15 EPE24649.1 - 5.1e-05 22.9 1.1 7.2 6.8 0.0 7.1 9 0 0 9 9 8 0 PPR repeat Abhydrolase_6 PF12697.2 EPE24649.1 - 8.1e-05 22.6 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 EPE24649.1 - 0.00034 20.7 0.0 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Vps39_1 PF10366.4 EPE24649.1 - 0.00053 19.9 12.0 3.9 7.5 0.2 5.3 2 2 4 6 6 5 1 Vacuolar sorting protein 39 domain 1 AAA_16 PF13191.1 EPE24649.1 - 0.0075 16.2 0.3 0.14 12.1 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain PGAP1 PF07819.8 EPE24649.1 - 0.0091 15.6 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_9 PF10081.4 EPE24649.1 - 0.019 13.6 0.0 0.48 9.0 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta-hydrolase family Abhydrolase_5 PF12695.2 EPE24649.1 - 0.019 14.7 0.0 0.07 12.8 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family NACHT PF05729.7 EPE24649.1 - 0.022 14.4 0.0 0.085 12.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain LCAT PF02450.10 EPE24649.1 - 0.024 13.6 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HlyD PF00529.15 EPE24649.1 - 0.044 13.0 4.3 2.5 7.3 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein DUF2305 PF10230.4 EPE24649.1 - 0.045 13.1 0.2 0.42 9.9 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) NTPase_1 PF03266.10 EPE24649.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 NTPase CbiA PF01656.18 EPE24649.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1996 PF09362.5 EPE24655.1 - 3.4e-79 265.8 0.3 3.4e-79 265.8 0.2 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) CPSF_A PF03178.10 EPE24656.1 - 1e-86 290.9 0.0 1.7e-85 286.9 0.0 2.6 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EPE24656.1 - 1.1e-06 27.1 0.0 5.6e-06 24.7 0.0 2.3 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.11 EPE24657.1 - 1.9e-16 59.7 0.2 1.9e-16 59.7 0.2 2.5 3 0 0 3 3 3 2 LMBR1-like membrane protein WD40 PF00400.27 EPE24658.1 - 3.9e-10 39.1 4.1 0.0005 19.8 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF162 PF02589.10 EPE24658.1 - 0.032 13.7 0.1 0.42 10.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised ACR, YkgG family COG1556 RNA_pol_N PF01194.12 EPE24659.1 - 1.3e-30 105.1 2.0 1.6e-30 104.9 1.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EPE24659.1 - 0.083 12.9 0.9 0.15 12.1 0.6 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Fer4_13 PF13370.1 EPE24660.1 - 4.7 7.6 7.1 29 5.1 0.0 4.4 4 1 0 4 4 4 0 4Fe-4S single cluster domain 4F5 PF04419.9 EPE24661.1 - 0.00018 22.1 7.2 0.00031 21.4 5.0 1.4 1 0 0 1 1 1 1 4F5 protein family HypA PF01155.14 EPE24661.1 - 0.048 13.3 0.2 0.06 13.0 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family AT_hook PF02178.14 EPE24662.1 - 5.8e-05 22.3 37.8 0.055 13.1 0.4 7.2 6 0 0 6 6 6 5 AT hook motif Glyoxalase_4 PF13669.1 EPE24662.1 - 0.087 12.8 0.2 0.28 11.2 0.1 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ank_2 PF12796.2 EPE24664.1 - 1e-109 359.0 20.2 2.5e-14 53.3 0.3 11.7 3 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 EPE24664.1 - 1.5e-94 305.4 33.8 6.9e-08 31.9 0.0 21.2 22 1 0 22 22 22 16 Ankyrin repeat Ank_4 PF13637.1 EPE24664.1 - 7.9e-81 265.1 22.3 3.2e-10 40.2 0.1 16.2 9 5 8 17 17 17 15 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE24664.1 - 4.1e-72 236.5 28.6 4.1e-08 33.1 0.0 16.6 7 5 13 20 20 20 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE24664.1 - 6.1e-70 224.1 17.3 0.00036 20.5 0.0 21.3 21 1 0 21 21 21 15 Ankyrin repeat SPRY PF00622.23 EPE24664.1 - 3.1e-12 46.6 0.1 9.6e-12 45.0 0.1 1.8 2 0 0 2 2 2 1 SPRY domain Peptidase_S8 PF00082.17 EPE24666.1 - 2.4e-14 53.1 0.1 4.3e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 Subtilase family Ank_3 PF13606.1 EPE24666.1 - 0.0015 18.5 0.0 4.1 7.9 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EPE24666.1 - 0.0018 18.7 0.0 3.3 8.3 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE24666.1 - 0.015 15.5 0.0 5 7.5 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DIOX_N PF14226.1 EPE24667.1 - 1.9e-28 99.3 0.0 3.1e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPE24667.1 - 5.5e-15 55.4 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NPR2 PF06218.6 EPE24669.1 - 8e-134 446.5 1.0 9.9e-112 373.7 0.6 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Methyltransf_16 PF10294.4 EPE24670.1 - 2.6e-17 62.8 0.0 4.9e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EPE24670.1 - 0.00015 21.3 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE24670.1 - 0.00053 20.5 0.2 0.002 18.6 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE24670.1 - 0.0016 17.8 0.1 0.17 11.2 0.1 3.0 2 1 1 3 3 3 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EPE24670.1 - 0.0056 16.4 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain IBR PF01485.16 EPE24671.1 - 1.1e-06 28.3 7.4 1.1e-06 28.3 5.1 3.6 2 2 1 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EPE24671.1 - 0.0076 16.0 10.0 0.0076 16.0 7.0 3.1 2 1 0 2 2 2 1 Ring finger domain RAP1 PF07218.6 EPE24671.1 - 1.9 6.4 8.6 2.8 5.9 5.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_M3 PF01432.15 EPE24672.1 - 1.9e-101 340.4 0.0 2.4e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF4589 PF15252.1 EPE24672.1 - 0.22 11.3 0.3 2.8 7.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) Glyco_hydro_76 PF03663.9 EPE24673.1 - 3.4e-22 79.3 7.9 2.1e-15 57.0 0.1 2.8 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 Hpr_kinase_C PF07475.7 EPE24673.1 - 0.058 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain FAD_binding_3 PF01494.14 EPE24674.1 - 1.6e-15 57.0 3.3 4.7e-12 45.6 0.7 3.0 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 EPE24674.1 - 7e-07 28.4 0.3 2.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EPE24674.1 - 4.5e-06 26.5 0.2 1.7e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPE24674.1 - 7.4e-06 26.2 0.1 0.039 14.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE24674.1 - 2e-05 24.5 0.3 0.0022 17.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPE24674.1 - 7.2e-05 22.0 1.4 9.2e-05 21.6 0.3 1.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EPE24674.1 - 0.00066 18.6 0.0 0.00092 18.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EPE24674.1 - 0.0016 17.0 0.0 0.0024 16.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EPE24674.1 - 0.0057 15.5 7.7 0.019 13.8 0.1 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPE24674.1 - 0.018 15.1 0.5 0.047 13.7 0.3 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EPE24674.1 - 0.082 12.4 0.1 0.082 12.4 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain RRM_1 PF00076.17 EPE24675.1 - 1.1e-16 60.1 0.0 1.7e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE24675.1 - 4.3e-13 49.0 0.0 7.1e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE24675.1 - 8.5e-08 31.9 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPE24675.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif BTB PF00651.26 EPE24676.1 - 0.0049 16.8 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EPE24677.1 - 0.00013 21.9 0.0 0.0007 19.5 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain BTB PF00651.26 EPE24678.1 - 0.0094 15.9 0.0 0.028 14.4 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EPE24679.1 - 0.0016 18.3 0.0 0.0061 16.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Thioredoxin_6 PF13848.1 EPE24679.1 - 0.0049 16.6 0.1 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Malic_M PF03949.10 EPE24681.1 - 2.5e-81 273.0 0.0 3.4e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EPE24681.1 - 4.9e-67 225.0 0.0 9.4e-67 224.1 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain AlaDh_PNT_C PF01262.16 EPE24681.1 - 0.066 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-C2H2 PF00096.21 EPE24682.1 - 0.00079 19.6 2.8 0.022 15.0 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE24682.1 - 0.0014 18.8 1.6 0.057 13.7 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPE24682.1 - 0.15 12.2 1.8 8.6 6.6 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EPE24682.1 - 0.17 12.0 0.9 4.4 7.5 0.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Glyco_hydro_67N PF03648.9 EPE24683.1 - 0.022 14.7 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus ERM PF00769.14 EPE24684.1 - 0.00037 20.0 15.7 0.00047 19.7 10.8 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Atg14 PF10186.4 EPE24684.1 - 0.017 14.0 9.8 0.024 13.5 6.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_pp85 PF04637.7 EPE24684.1 - 0.18 10.0 6.6 0.27 9.4 4.6 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Asp-B-Hydro_N PF05279.6 EPE24684.1 - 1 9.1 11.3 1.4 8.7 7.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region OSTbeta PF15048.1 EPE24684.1 - 1.8 8.6 5.3 3 7.9 3.7 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein HAUS6_N PF14661.1 EPE24684.1 - 3.4 6.9 10.8 5.4 6.2 7.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PAP2_3 PF14378.1 EPE24685.1 - 1.7e-18 66.8 16.5 1.6e-11 44.1 0.1 4.0 4 1 0 4 4 4 3 PAP2 superfamily PAP2_C PF14360.1 EPE24685.1 - 0.035 14.3 1.4 0.074 13.3 0.1 2.2 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Metallophos PF00149.23 EPE24687.1 - 1e-07 31.5 8.0 4.6e-07 29.4 5.5 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1399 PF07173.7 EPE24689.1 - 9e-19 68.1 0.1 5e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) DUF1045 PF06299.7 EPE24689.1 - 0.0017 18.0 0.1 0.0046 16.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1045) Rifin_STEVOR PF02009.11 EPE24690.1 - 0.0016 18.1 0.9 0.0031 17.1 0.6 1.4 1 0 0 1 1 1 1 Rifin/stevor family ATP-synt_B PF00430.13 EPE24690.1 - 4.4 7.1 7.3 7.1 6.4 4.3 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) NIF PF03031.13 EPE24693.1 - 4.6e-37 127.1 0.0 6.7e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase YndJ PF14158.1 EPE24693.1 - 0.22 10.5 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 YndJ-like protein DUF605 PF04652.11 EPE24693.1 - 2.5 7.4 24.4 3.8 6.7 16.9 1.2 1 0 0 1 1 1 0 Vta1 like Hydrolase PF00702.21 EPE24694.1 - 2.8e-20 73.6 0.4 3.9e-16 60.1 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EPE24694.1 - 2e-18 66.2 0.0 5.2e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EPE24694.1 - 2.8e-12 46.4 0.0 1e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPE24694.1 - 4.3e-12 46.6 0.2 3.4e-11 43.6 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPE24694.1 - 1.7e-05 24.5 0.3 0.016 14.8 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ICMT PF04140.9 EPE24695.1 - 4.7e-10 39.5 1.5 2.9e-08 33.7 0.1 2.6 1 1 1 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EPE24695.1 - 3.6e-07 30.2 3.7 4.7e-06 26.6 0.1 2.9 2 1 0 3 3 3 2 Phospholipid methyltransferase HisKA_3 PF07730.8 EPE24697.1 - 0.24 11.7 1.2 10 6.5 0.2 3.0 3 0 0 3 3 3 0 Histidine kinase AAA PF00004.24 EPE24698.1 - 5.5e-20 71.9 0.0 1.1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE24698.1 - 0.035 14.2 0.2 0.18 11.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EPE24698.1 - 0.038 13.9 0.0 0.038 13.9 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain DUF3145 PF11343.3 EPE24698.1 - 0.046 13.1 0.2 0.46 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) AAA_17 PF13207.1 EPE24698.1 - 0.061 14.1 0.5 0.39 11.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EPE24698.1 - 0.82 9.9 0.0 0.82 9.9 0.0 3.5 4 0 0 4 4 4 0 AAA domain BTB PF00651.26 EPE24699.1 - 1.2e-07 31.7 0.2 0.0031 17.5 0.0 3.2 3 0 0 3 3 3 2 BTB/POZ domain BTB PF00651.26 EPE24700.1 - 8.2e-06 25.7 0.0 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 EPE24701.1 - 3.1e-06 27.1 0.5 0.00082 19.3 0.1 2.2 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 EPE24703.1 - 8.9e-08 32.1 0.5 0.00022 21.1 0.1 2.3 2 0 0 2 2 2 2 BTB/POZ domain Peptidase_S8 PF00082.17 EPE24704.1 - 4.8e-46 157.1 12.9 8.1e-46 156.4 8.9 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EPE24704.1 - 7.5e-10 39.2 0.1 1.6e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Methyltrans_SAM PF10672.4 EPE24704.1 - 0.03 13.1 0.3 0.23 10.2 0.2 2.0 2 0 0 2 2 2 0 S-adenosylmethionine-dependent methyltransferase SKG6 PF08693.5 EPE24706.1 - 0.024 13.9 0.1 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Acetyltransf_7 PF13508.1 EPE24707.1 - 4.1e-08 33.2 0.0 5.6e-07 29.6 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE24707.1 - 3.3e-07 30.4 0.1 1.7e-06 28.1 0.0 2.0 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE24707.1 - 1.1e-06 28.6 0.1 1.8e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.13 EPE24707.1 - 0.00031 20.0 0.0 0.00048 19.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_9 PF13527.1 EPE24707.1 - 0.0036 17.1 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE24707.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein ADH_N PF08240.7 EPE24708.1 - 1e-26 92.8 3.2 1e-26 92.8 2.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE24708.1 - 3.8e-18 65.2 0.0 6.1e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EPE24708.1 - 0.0019 17.8 0.1 0.0031 17.1 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Zip PF02535.17 EPE24709.1 - 3.3e-49 167.6 1.3 4e-49 167.3 0.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Vma12 PF11712.3 EPE24709.1 - 0.11 12.2 0.2 0.93 9.1 0.0 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3357 PF11837.3 EPE24709.1 - 0.11 12.3 1.4 3.7 7.4 0.0 3.5 4 1 1 5 5 5 0 Domain of unknown function (DUF3357) Pec_lyase_C PF00544.14 EPE24710.1 - 1.1e-16 60.9 4.2 1.8e-16 60.2 2.9 1.3 1 0 0 1 1 1 1 Pectate lyase Methyltransf_11 PF08241.7 EPE24714.1 - 1.5e-17 63.8 0.0 2.4e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE24714.1 - 1.8e-15 57.0 0.0 2.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE24714.1 - 2.4e-15 56.4 0.0 3.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE24714.1 - 3.2e-12 46.7 0.0 4.7e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE24714.1 - 9.3e-12 45.5 0.0 1.4e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE24714.1 - 1e-09 38.6 0.0 2.3e-09 37.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE24714.1 - 3.5e-08 33.4 0.0 6.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE24714.1 - 1.7e-05 24.0 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EPE24714.1 - 2.7e-05 23.0 0.0 3.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.7 EPE24714.1 - 8.3e-05 22.0 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EPE24714.1 - 0.00012 21.4 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EPE24714.1 - 0.00014 21.0 0.0 0.00019 20.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EPE24714.1 - 0.00027 20.1 0.0 0.00036 19.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 EPE24714.1 - 0.00061 19.0 0.0 0.00092 18.4 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 EPE24714.1 - 0.079 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 EPE24714.1 - 0.17 11.4 0.0 0.43 10.1 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase LRR_8 PF13855.1 EPE24716.1 - 1.8e-19 69.2 15.5 3e-10 39.6 1.2 4.1 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EPE24716.1 - 4.6e-19 67.6 7.3 2.6e-06 26.8 0.0 4.8 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) Pkinase PF00069.20 EPE24716.1 - 1.2e-16 60.6 0.0 2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE24716.1 - 1.5e-15 57.0 0.0 8.7e-15 54.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase LRR_1 PF00560.28 EPE24716.1 - 1.6e-14 51.7 5.9 0.0079 16.0 0.1 6.6 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EPE24716.1 - 2.6e-07 29.7 8.3 3.7 8.1 0.1 6.6 7 0 0 7 7 7 3 Leucine rich repeat Kdo PF06293.9 EPE24716.1 - 2.1e-06 26.9 0.1 3.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.1 EPE24716.1 - 0.0014 18.4 4.5 4.8 7.5 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich repeat Kinase-like PF14531.1 EPE24716.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EPE24716.1 - 0.12 12.0 0.2 0.23 11.1 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family p450 PF00067.17 EPE24717.1 - 6.1e-66 222.8 0.0 8.1e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_6 PF00970.19 EPE24718.1 - 2.9e-27 94.6 0.0 4.2e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EPE24718.1 - 1e-22 80.7 0.0 1.6e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_9 PF08021.6 EPE24718.1 - 0.00058 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_6 PF08030.7 EPE24718.1 - 0.002 18.0 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain 3HCDH_N PF02737.13 EPE24719.1 - 5e-30 104.4 0.0 7.2e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EPE24719.1 - 2.9e-15 56.4 0.0 7e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EPE24719.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EPE24719.1 - 0.0036 17.1 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ldl_recept_b PF00058.12 EPE24719.1 - 0.008 16.4 0.5 1.3 9.4 0.0 4.1 5 0 0 5 5 5 1 Low-density lipoprotein receptor repeat class B F420_oxidored PF03807.12 EPE24719.1 - 0.031 14.7 0.0 0.079 13.3 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EPE24719.1 - 0.067 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HET PF06985.6 EPE24720.1 - 2.1e-25 89.4 0.0 4.5e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Actin PF00022.14 EPE24721.1 - 3.7e-130 433.8 0.0 4.2e-130 433.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPE24721.1 - 1.2e-07 30.6 0.0 0.02 13.5 0.0 3.1 2 1 1 3 3 3 3 MreB/Mbl protein D-ser_dehydrat PF14031.1 EPE24722.1 - 7.8e-24 83.6 0.0 1.9e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EPE24722.1 - 8.1e-15 54.9 0.0 1.2e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Pkinase PF00069.20 EPE24724.1 - 1.2e-11 44.2 0.4 1.4e-07 30.9 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE24724.1 - 0.032 13.3 0.0 0.074 12.1 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Kdo PF06293.9 EPE24724.1 - 0.039 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE24724.1 - 0.052 13.2 0.1 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 EPE24725.1 - 5.1e-47 160.2 56.9 5.1e-46 157.0 38.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE24725.1 - 3.2e-17 62.2 9.8 3.2e-17 62.2 6.8 3.5 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EPE24725.1 - 7.5e-15 54.1 24.3 3.1e-14 52.0 16.8 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CorA PF01544.13 EPE24726.1 - 0.00084 18.4 2.3 0.0015 17.6 1.2 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2269 PF10027.4 EPE24726.1 - 0.071 12.8 0.2 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) BatD PF13584.1 EPE24726.1 - 0.096 11.2 0.1 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF4381 PF14316.1 EPE24726.1 - 0.26 11.4 0.2 0.26 11.4 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF3490 PF11995.3 EPE24726.1 - 1.1 8.8 6.0 1.2 8.6 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3490) UPF0197 PF05251.7 EPE24727.1 - 8.2 6.8 8.3 15 5.9 0.4 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0197) F-box-like PF12937.2 EPE24728.1 - 1.8e-11 43.5 0.0 3.3e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE24728.1 - 0.00025 20.5 0.1 0.0011 18.5 0.0 2.0 2 0 0 2 2 2 1 F-box domain MIT PF04212.13 EPE24728.1 - 0.059 13.2 0.1 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 EPE24729.1 - 1.1e-66 220.6 0.2 5.1e-22 77.3 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein UDG PF03167.14 EPE24730.1 - 1.8e-23 82.6 0.1 2.7e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Macoilin PF09726.4 EPE24730.1 - 0.74 8.0 7.5 1.1 7.4 5.2 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF3140 PF11338.3 EPE24731.1 - 1e-28 99.2 1.5 1.2e-28 99.0 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) TMA7 PF09072.5 EPE24731.1 - 0.27 11.7 2.0 0.5 10.8 1.4 1.5 1 0 0 1 1 1 0 Translation machinery associated TMA7 DUF1708 PF08101.6 EPE24732.1 - 1.6e-153 511.5 0.0 2e-153 511.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) SRF-TF PF00319.13 EPE24733.1 - 4e-24 83.5 0.2 6.2e-24 82.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HET PF06985.6 EPE24734.1 - 9.9e-35 119.7 1.7 1.9e-34 118.7 1.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EPE24735.1 - 4.2e-19 68.4 38.3 4.2e-19 68.4 26.6 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE24735.1 - 4.8e-05 22.1 14.9 0.0034 16.0 2.7 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter DUF1049 PF06305.6 EPE24735.1 - 0.037 13.5 0.1 0.037 13.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Ribosomal_L14 PF00238.14 EPE24736.1 - 2.1e-32 111.4 0.0 2.3e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.14 EPE24737.1 - 1.8e-79 267.2 0.5 2.9e-79 266.6 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.16 EPE24738.1 - 1e-34 118.6 0.0 1.8e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EPE24738.1 - 4.8e-27 94.3 1.7 6e-27 94.0 0.5 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EPE24738.1 - 5.6e-09 35.5 0.0 1.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RasGAP_C PF03836.10 EPE24739.1 - 4.7e-49 165.7 2.6 1.3e-48 164.2 1.8 1.8 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EPE24739.1 - 4.4e-45 153.7 0.1 1.6e-44 151.9 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 EPE24739.1 - 2.8e-10 40.1 0.0 1.1e-09 38.3 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.22 EPE24739.1 - 3.6e-10 38.5 26.6 3.9 7.3 0.0 12.3 14 0 0 14 14 14 5 IQ calmodulin-binding motif DNA_repr_REX1B PF14966.1 EPE24739.1 - 0.0027 18.0 3.9 0.092 13.1 0.4 3.6 1 1 1 2 2 2 1 DNA repair REX1-B IMPDH PF00478.20 EPE24740.1 - 9.8e-131 435.8 5.6 1.2e-130 435.5 3.9 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EPE24740.1 - 4.2e-18 64.8 0.1 2.3e-09 36.8 0.1 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EPE24740.1 - 1.2e-06 27.9 7.3 0.012 14.7 0.0 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EPE24740.1 - 1.5e-06 27.3 1.4 1.5e-05 24.0 0.3 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EPE24740.1 - 0.0053 16.0 1.1 0.026 13.7 0.8 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein PK PF00224.16 EPE24740.1 - 0.014 14.0 0.0 0.062 11.9 0.0 1.9 2 1 0 2 2 2 0 Pyruvate kinase, barrel domain P53_TAD PF08563.6 EPE24741.1 - 3.8 6.6 5.1 0.46 9.6 0.2 1.9 2 0 0 2 2 2 0 P53 transactivation motif DUF2730 PF10805.3 EPE24743.1 - 0.042 13.5 0.1 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) adh_short PF00106.20 EPE24744.1 - 8.9e-15 54.9 0.0 1.1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE24744.1 - 7.2e-07 29.2 0.0 1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE24744.1 - 1e-06 28.5 0.0 1.4e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE24744.1 - 1.6e-05 24.4 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sigma54_activ_2 PF14532.1 EPE24744.1 - 0.098 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain EthD PF07110.6 EPE24745.1 - 3.1e-09 37.6 0.3 4.2e-09 37.2 0.2 1.2 1 0 0 1 1 1 1 EthD domain BTB PF00651.26 EPE24746.1 - 0.01 15.8 0.9 0.035 14.1 0.2 2.2 3 0 0 3 3 3 0 BTB/POZ domain MtrG PF04210.8 EPE24746.1 - 0.018 14.7 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G BTB PF00651.26 EPE24747.1 - 3.4e-07 30.2 0.5 0.0014 18.5 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain BTB PF00651.26 EPE24748.1 - 4.2e-06 26.7 0.9 0.0068 16.3 0.0 3.1 3 1 0 3 3 3 2 BTB/POZ domain DEAD PF00270.24 EPE24748.1 - 0.1 12.1 0.0 0.28 10.6 0.0 1.6 1 1 1 2 2 2 0 DEAD/DEAH box helicase TFR_dimer PF04253.10 EPE24752.1 - 2.2e-19 69.2 0.0 4.3e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EPE24752.1 - 1.6e-14 54.0 0.0 5.6e-14 52.2 0.0 1.9 3 0 0 3 3 3 1 Peptidase family M28 PA PF02225.17 EPE24752.1 - 7.6e-05 22.3 0.1 0.0002 20.9 0.0 1.7 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 EPE24752.1 - 0.077 12.2 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Nicastrin MFS_1 PF07690.11 EPE24753.1 - 5.2e-32 110.9 34.1 6.7e-27 94.1 7.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE24753.1 - 4.8e-12 45.1 2.6 4.8e-12 45.1 1.8 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EPE24753.1 - 0.00018 20.0 1.2 0.00018 20.0 0.8 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.11 EPE24755.1 - 1.1e-29 103.2 36.0 1.1e-29 103.2 25.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.1 EPE24756.1 - 5.2e-18 65.6 0.1 1.2e-17 64.4 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPE24756.1 - 7.3e-14 51.8 0.2 8.9e-13 48.3 0.0 2.6 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily HET PF06985.6 EPE24757.1 - 6.5e-36 123.5 0.5 1.2e-35 122.7 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clr2 PF10383.4 EPE24757.1 - 0.019 14.9 0.1 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 BNR_2 PF13088.1 EPE24758.1 - 0.0027 17.0 0.1 0.041 13.1 0.0 2.1 1 1 1 2 2 2 1 BNR repeat-like domain BNR PF02012.15 EPE24758.1 - 0.019 14.7 0.9 2.5 8.2 0.2 3.3 2 0 0 2 2 2 0 BNR/Asp-box repeat Aldo_ket_red PF00248.16 EPE24759.1 - 2.3e-48 164.4 0.0 2.6e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_25 PF13649.1 EPE24760.1 - 0.0011 19.3 0.0 0.002 18.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE24760.1 - 0.0017 18.1 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE24760.1 - 0.0025 18.2 0.0 0.025 15.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Aldo_ket_red PF00248.16 EPE24761.1 - 1.1e-55 188.5 0.0 1.2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_Tnp_1 PF01527.15 EPE24761.1 - 0.041 13.8 0.1 0.55 10.2 0.1 2.3 2 0 0 2 2 2 0 Transposase RHH_1 PF01402.16 EPE24761.1 - 0.38 10.7 3.7 8 6.5 0.0 2.8 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family p450 PF00067.17 EPE24762.1 - 3e-47 161.2 0.0 3.9e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 V-ATPase_H_C PF11698.3 EPE24762.1 - 0.063 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 V-ATPase subunit H Peptidase_A4 PF01828.12 EPE24763.1 - 8.1e-10 38.1 0.7 1.4e-09 37.3 0.5 1.3 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_A4 PF01828.12 EPE24764.1 - 7.5e-10 38.2 0.1 8.5e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase A4 family Abhydrolase_6 PF12697.2 EPE24766.1 - 1e-31 110.5 0.5 1.3e-31 110.2 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE24766.1 - 4.6e-15 55.8 0.0 2.4e-14 53.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE24766.1 - 3.9e-13 49.3 0.0 6.2e-13 48.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE24766.1 - 6.4e-09 35.5 0.0 1.5e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EPE24766.1 - 1.5e-07 31.2 0.0 1.8e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EPE24766.1 - 0.00025 20.3 0.0 0.0007 18.9 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.6 EPE24766.1 - 0.00052 18.9 0.0 0.00085 18.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EPE24766.1 - 0.0052 15.7 0.0 0.0088 14.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.8 EPE24766.1 - 0.024 14.2 0.3 0.053 13.0 0.1 1.6 2 0 0 2 2 2 0 PGAP1-like protein Peptidase_S9 PF00326.16 EPE24766.1 - 0.033 13.4 0.0 0.54 9.4 0.0 2.6 3 1 0 3 3 3 0 Prolyl oligopeptidase family CLPTM1 PF05602.7 EPE24767.1 - 5.7 5.5 9.3 6.9 5.2 6.5 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) cwf18 PF08315.7 EPE24767.1 - 6.9 7.1 14.6 1.6e+02 2.7 10.1 2.2 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor SLAC1 PF03595.12 EPE24768.1 - 1.5e-91 306.5 52.6 1.7e-91 306.3 36.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Ank_2 PF12796.2 EPE24770.1 - 3.3e-43 145.9 0.0 1.1e-13 51.3 0.0 5.8 4 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPE24770.1 - 2.1e-30 101.7 1.9 0.0019 18.2 0.0 13.9 15 1 1 16 16 16 7 Ankyrin repeat Ank PF00023.25 EPE24770.1 - 7.5e-30 101.2 4.8 0.0006 19.4 0.0 11.7 11 1 1 12 12 12 7 Ankyrin repeat Ank_4 PF13637.1 EPE24770.1 - 1.1e-25 89.4 0.1 0.013 16.0 0.0 11.2 7 4 5 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE24770.1 - 1.5e-15 56.8 1.4 0.046 13.9 0.0 8.2 7 2 1 8 8 8 4 Ankyrin repeats (many copies) ABC_tran PF00005.22 EPE24772.1 - 3e-46 157.1 0.6 1.1e-25 90.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EPE24772.1 - 6.7e-29 101.0 52.3 1.3e-19 70.4 18.0 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EPE24772.1 - 3.1e-21 76.6 2.2 7.8e-05 22.7 0.0 4.7 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EPE24772.1 - 1.4e-09 37.3 3.1 0.0002 20.8 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EPE24772.1 - 5.1e-07 29.1 3.6 0.18 11.0 0.0 3.6 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EPE24772.1 - 2.5e-06 26.7 1.0 0.033 13.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EPE24772.1 - 6.9e-06 26.5 6.3 0.027 14.7 0.6 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPE24772.1 - 1.4e-05 25.1 0.6 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane PF01061.19 EPE24772.1 - 5.6e-05 22.4 16.7 5.6e-05 22.4 11.5 4.5 5 1 0 5 5 4 1 ABC-2 type transporter AAA_15 PF13175.1 EPE24772.1 - 0.00063 18.8 0.0 0.16 10.9 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EPE24772.1 - 0.00079 18.8 0.1 0.39 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE24772.1 - 0.002 18.2 0.5 0.37 10.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain MutS_V PF00488.16 EPE24772.1 - 0.0091 15.4 0.4 0.47 9.8 0.1 2.5 2 0 0 2 2 2 1 MutS domain V AAA_30 PF13604.1 EPE24772.1 - 0.018 14.6 1.0 5.1 6.6 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPE24772.1 - 0.025 14.3 3.3 5 6.9 0.2 3.4 3 0 0 3 3 3 0 Part of AAA domain SRP54 PF00448.17 EPE24772.1 - 0.041 13.3 0.9 9.1 5.6 0.3 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EPE24772.1 - 0.044 12.8 0.5 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.1 EPE24772.1 - 0.052 13.5 3.6 4.1 7.3 0.3 3.3 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EPE24772.1 - 0.074 12.9 0.1 9.2 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EPE24772.1 - 0.079 11.4 0.7 1 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EPE24772.1 - 0.083 12.7 0.0 16 5.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EPE24772.1 - 0.13 12.4 0.0 17 5.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 EPE24772.1 - 0.13 11.6 2.7 4.8 6.5 0.7 2.4 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 EPE24772.1 - 0.17 12.4 0.1 6.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein G-alpha PF00503.15 EPE24772.1 - 0.2 10.2 0.0 1.3 7.5 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit AIG1 PF04548.11 EPE24772.1 - 4.7 6.2 4.8 4.5 6.3 1.0 2.3 2 0 0 2 2 2 0 AIG1 family DUF605 PF04652.11 EPE24773.1 - 2.8e-103 346.2 20.2 2.3e-101 339.9 14.0 2.0 1 1 0 1 1 1 1 Vta1 like Thioredoxin PF00085.15 EPE24774.1 - 4.1e-32 109.9 0.0 5.1e-25 87.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.1 EPE24774.1 - 4.7e-06 26.6 0.3 0.15 12.2 0.0 4.6 3 3 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EPE24774.1 - 0.00052 20.1 9.8 0.027 14.6 2.4 3.8 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EPE24774.1 - 0.035 13.8 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_7 PF13899.1 EPE24774.1 - 0.092 12.7 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.6 EPE24774.1 - 0.093 12.6 0.0 2.2 8.2 0.0 3.0 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE RNase_PH PF01138.16 EPE24775.1 - 3.5e-34 117.9 0.1 5e-34 117.4 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ER_lumen_recept PF00810.13 EPE24776.1 - 3.8e-37 128.0 5.2 6.2e-37 127.3 3.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EPE24776.1 - 0.0029 17.1 7.9 0.021 14.3 0.0 3.1 3 0 0 3 3 3 2 PQ loop repeat MreB_Mbl PF06723.8 EPE24777.1 - 0.0012 17.5 0.1 0.0023 16.5 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein DcuC PF03606.10 EPE24778.1 - 0.1 10.8 0.0 0.14 10.3 0.0 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF3951 PF13131.1 EPE24778.1 - 0.13 12.0 1.7 0.26 11.1 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) APG6 PF04111.7 EPE24780.1 - 0.42 9.6 7.2 0.74 8.7 5.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 HSP70 PF00012.15 EPE24781.1 - 0.0025 15.8 0.1 0.011 13.6 0.1 2.0 2 1 0 2 2 2 1 Hsp70 protein zf-MYND PF01753.13 EPE24783.1 - 1.3e-09 37.8 12.3 2.3e-09 36.9 8.5 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EPE24783.1 - 0.14 11.8 8.2 0.27 10.9 5.7 1.5 1 0 0 1 1 1 0 HIT zinc finger DZR PF12773.2 EPE24783.1 - 0.23 11.2 6.9 0.56 10.0 4.8 1.7 1 0 0 1 1 1 0 Double zinc ribbon Ribonuclease_3 PF00636.21 EPE24784.1 - 1.1e-08 35.4 0.0 3.2e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EPE24784.1 - 6.3e-08 32.6 0.0 7.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like zf-His_Me_endon PF05551.6 EPE24785.1 - 0.21 11.5 0.9 0.44 10.5 0.6 1.5 1 1 0 1 1 1 0 Zinc-binding loop region of homing endonuclease TPR_10 PF13374.1 EPE24786.1 - 3e-48 160.4 6.1 2e-13 49.8 0.0 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EPE24786.1 - 5e-47 157.7 14.7 7.6e-17 61.0 0.1 3.2 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 EPE24786.1 - 2.2e-14 51.9 5.2 0.00086 18.9 0.1 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPE24786.1 - 3.2e-13 48.6 4.4 0.007 15.9 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPE24786.1 - 3.9e-13 48.4 2.5 0.048 13.8 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EPE24786.1 - 3.6e-12 45.7 14.2 3.7e-06 26.4 0.2 3.2 1 1 3 4 4 4 4 TPR repeat TPR_16 PF13432.1 EPE24786.1 - 4.2e-12 46.3 1.4 1.1e-06 29.1 0.2 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPE24786.1 - 1.1e-11 43.6 1.9 0.0094 15.8 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 EPE24786.1 - 5.6e-10 38.6 0.1 0.08 13.4 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EPE24786.1 - 4.2e-08 33.2 1.2 0.099 12.7 0.0 3.4 1 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EPE24786.1 - 2.5e-06 27.7 3.5 0.22 11.8 0.3 3.8 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_3 PF07720.7 EPE24786.1 - 1.1e-05 25.1 1.5 0.012 15.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPE24786.1 - 1.6e-05 24.2 6.3 0.019 14.6 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE24786.1 - 0.00032 21.0 4.4 1.4 9.7 0.3 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat PPR PF01535.15 EPE24786.1 - 0.0015 18.3 0.1 4.7 7.4 0.0 3.8 4 0 0 4 4 4 1 PPR repeat Surp PF01805.15 EPE24786.1 - 0.002 17.7 0.1 2.5 7.8 0.0 2.8 3 0 0 3 3 3 2 Surp module TPR_20 PF14561.1 EPE24786.1 - 0.0033 17.5 4.8 6.8 6.8 0.0 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat Gly_radical PF01228.16 EPE24786.1 - 0.0065 16.8 0.2 0.84 10.0 0.0 2.6 1 1 1 2 2 2 1 Glycine radical Rab5-bind PF09311.6 EPE24786.1 - 0.0098 15.7 2.0 8.1 6.2 0.0 3.4 1 1 1 3 3 3 0 Rabaptin-like protein DUF3366 PF11846.3 EPE24786.1 - 0.056 13.3 0.5 1.9 8.3 0.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) TPR_9 PF13371.1 EPE24786.1 - 0.057 13.2 0.2 0.81 9.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat FTCD PF02971.9 EPE24786.1 - 0.077 12.6 0.0 28 4.3 0.0 2.9 1 1 2 3 3 3 0 Formiminotransferase domain CH PF00307.26 EPE24786.1 - 0.14 12.2 0.3 3.9 7.5 0.0 2.6 1 1 2 3 3 3 0 Calponin homology (CH) domain DUF4404 PF14357.1 EPE24786.1 - 0.15 12.4 3.5 8.8 6.8 0.3 3.1 2 1 2 4 4 3 0 Domain of unknown function (DUF4404) TPR_6 PF13174.1 EPE24786.1 - 0.18 12.3 7.0 0.7 10.4 0.0 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat Patatin PF01734.17 EPE24787.1 - 7e-25 88.1 0.0 1.8e-24 86.8 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.17 EPE24787.1 - 3.6e-10 39.1 0.0 5.2e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EPE24787.1 - 1.5e-07 31.6 0.0 4e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EPE24787.1 - 4.8e-06 26.3 0.0 9.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPE24787.1 - 6.3e-06 26.3 0.1 1.6e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain TPR_10 PF13374.1 EPE24787.1 - 0.00013 21.7 0.2 0.002 17.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2285 PF10074.4 EPE24787.1 - 0.13 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) RdRP_5 PF07925.6 EPE24788.1 - 0.097 10.0 0.0 0.13 9.5 0.0 1.1 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 p450 PF00067.17 EPE24789.1 - 2e-45 155.1 0.0 2.5e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy_3 PF13640.1 EPE24790.1 - 1.1e-09 38.6 0.0 1.9e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EPE24790.1 - 9.6e-07 28.3 0.0 2.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPE24790.1 - 0.048 13.9 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Asp PF00026.18 EPE24792.1 - 1.3e-12 47.5 0.0 2e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF2001 PF09393.5 EPE24793.1 - 0.031 13.9 4.1 0.059 13.0 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2001) Acetyltransf_1 PF00583.19 EPE24794.1 - 1.4e-05 25.0 0.0 0.00014 21.7 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE24794.1 - 0.00024 21.1 0.0 0.00047 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1900 PF08954.6 EPE24795.1 - 5.9e-49 165.0 0.0 5.1e-48 162.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EPE24795.1 - 1.5e-34 117.4 0.1 2.5e-34 116.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EPE24795.1 - 7.8e-27 92.1 1.1 7.5e-08 31.9 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EPE24795.1 - 0.00013 20.2 0.1 0.21 9.6 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 MFS_1 PF07690.11 EPE24797.1 - 1.7e-35 122.3 21.9 5.1e-33 114.2 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GMC_oxred_C PF05199.8 EPE24797.1 - 5.6e-33 114.2 0.0 1e-32 113.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EPE24797.1 - 2.6e-32 112.1 0.0 3.1e-25 88.9 0.0 2.8 1 1 1 2 2 2 2 GMC oxidoreductase DAO PF01266.19 EPE24797.1 - 8.1e-05 21.6 0.0 0.15 10.9 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase DUF1228 PF06779.9 EPE24797.1 - 0.00011 22.1 1.4 0.00037 20.4 0.4 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1228) DUF1248 PF06852.7 EPE24797.1 - 0.02 14.1 0.0 0.05 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) NAD_binding_8 PF13450.1 EPE24797.1 - 0.072 13.1 0.0 0.27 11.3 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE24797.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein APH PF01636.18 EPE24799.1 - 3.2e-17 63.0 0.0 1.1e-16 61.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EPE24799.1 - 0.00053 18.7 0.0 0.11 11.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.15 EPE24799.1 - 0.0083 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Acetyltransf_3 PF13302.1 EPE24801.1 - 1.4e-18 67.4 0.0 1.9e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE24801.1 - 1.5e-08 34.4 0.1 2.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EPE24801.1 - 0.089 12.6 0.0 0.18 11.7 0.0 1.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NAP PF00956.13 EPE24802.1 - 2.6e-47 160.9 0.0 3.7e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) BUD22 PF09073.5 EPE24802.1 - 0.23 10.5 7.7 0.27 10.2 5.3 1.2 1 0 0 1 1 1 0 BUD22 Asparaginase PF00710.15 EPE24803.1 - 4.2e-100 334.6 0.0 5.6e-100 334.2 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EPE24803.1 - 2.2e-13 50.3 0.2 4.1e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE24803.1 - 1.7e-11 43.2 0.2 4.4e-06 26.2 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EPE24803.1 - 6.2e-11 42.5 0.1 1.1e-09 38.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE24803.1 - 5.9e-10 39.0 0.1 2e-07 31.0 0.2 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE24803.1 - 3.9e-08 32.7 0.3 0.018 15.2 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat DUF2629 PF10945.3 EPE24803.1 - 0.0038 16.5 0.1 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2629) PTR2 PF00854.16 EPE24804.1 - 5e-49 167.0 11.0 4.4e-48 163.9 7.6 2.0 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EPE24804.1 - 4.2e-13 48.7 19.9 6.7e-13 48.0 12.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Beta-lactamase PF00144.19 EPE24805.1 - 1.5e-50 172.0 0.0 2.1e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EPE24805.1 - 9.3e-10 38.2 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Peptidase_S11 PF00768.15 EPE24805.1 - 0.01 15.1 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase p450 PF00067.17 EPE24806.1 - 1.8e-49 168.5 0.0 2.3e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 EPE24807.1 - 7.7e-13 48.7 0.0 1.7e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EPE24808.1 - 7.9e-18 64.5 0.0 6e-09 36.1 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE24808.1 - 1.3e-13 51.0 0.6 2.1e-06 28.0 0.1 4.5 3 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE24808.1 - 4.1e-10 39.5 0.3 4e-06 26.8 0.2 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EPE24808.1 - 6.2e-09 35.2 0.1 4.3e-05 23.1 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 EPE24808.1 - 1.2e-07 31.2 1.5 0.0021 18.1 0.0 5.9 7 0 0 7 7 7 1 Ankyrin repeat DZF PF07528.9 EPE24808.1 - 0.02 14.2 0.3 0.045 13.1 0.0 1.7 2 0 0 2 2 2 0 DZF domain MscS_porin PF12795.2 EPE24808.1 - 0.044 13.1 0.2 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain UPF0029 PF01205.14 EPE24809.1 - 1e-31 108.8 0.0 2e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EPE24809.1 - 5.1e-11 42.4 0.0 1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 EPE24809.1 - 0.038 13.4 0.0 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme AIG2 PF06094.7 EPE24812.1 - 5.4e-10 39.6 0.0 1.1e-09 38.7 0.0 1.5 2 0 0 2 2 2 1 AIG2-like family DUF1244 PF06844.6 EPE24812.1 - 0.09 12.6 0.2 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Chitin_bind_3 PF03067.10 EPE24813.1 - 7.8e-05 23.0 0.0 0.0002 21.6 0.0 1.7 2 0 0 2 2 2 1 Chitin binding domain Pyr_redox_3 PF13738.1 EPE24814.1 - 5.7e-28 98.3 0.0 1.1e-27 97.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE24814.1 - 3.4e-21 75.0 0.5 5.2e-20 71.1 0.3 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPE24814.1 - 7.2e-11 41.5 0.9 1.2e-08 34.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EPE24814.1 - 1.1e-08 35.0 0.0 3e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE24814.1 - 9.9e-08 32.0 0.0 8.8e-06 25.7 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE24814.1 - 3e-06 26.3 0.1 4.6e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE24814.1 - 5.4e-06 25.5 0.7 1.7e-05 23.9 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPE24814.1 - 0.00074 19.3 0.0 0.0026 17.5 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EPE24814.1 - 0.0013 17.8 0.0 0.0025 16.9 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPE24814.1 - 0.0014 17.7 0.2 0.037 13.0 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EPE24814.1 - 0.0018 17.4 0.1 0.004 16.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.15 EPE24814.1 - 0.0034 17.4 0.9 0.42 10.7 0.0 3.0 3 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EPE24814.1 - 0.0053 15.2 0.6 0.027 12.9 0.5 2.1 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.19 EPE24814.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Strep_67kDa_ant PF06100.6 EPE24814.1 - 0.04 12.2 0.0 0.062 11.6 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Lycopene_cycl PF05834.7 EPE24814.1 - 0.054 12.4 0.0 0.099 11.5 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EPE24814.1 - 0.061 13.7 0.1 2.2 8.7 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.23 EPE24815.1 - 9.5e-43 146.1 0.0 1.5e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme 7tm_4 PF13853.1 EPE24815.1 - 0.068 12.9 1.9 0.13 12.0 1.3 1.4 1 0 0 1 1 1 0 Olfactory receptor DUF1757 PF08560.5 EPE24816.1 - 2.2e-06 27.4 0.0 3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) TPR_2 PF07719.12 EPE24817.1 - 2.2e-31 105.2 9.6 0.00026 20.6 0.2 10.5 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 EPE24817.1 - 2.3e-29 100.8 11.4 5.4e-10 38.7 0.0 7.6 5 2 1 7 7 7 6 TPR repeat TPR_1 PF00515.23 EPE24817.1 - 1.1e-27 94.4 1.0 6.4e-05 22.3 0.4 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat Apc3 PF12895.2 EPE24817.1 - 2.3e-27 94.9 17.3 6.1e-22 77.5 0.5 6.0 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EPE24817.1 - 9e-23 80.0 13.4 2.3e-11 43.4 0.0 8.5 7 3 1 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPE24817.1 - 2.8e-20 72.4 6.9 0.0023 18.2 0.0 7.6 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EPE24817.1 - 2.6e-17 61.7 5.5 0.0047 17.4 0.0 9.4 5 3 5 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPE24817.1 - 4.8e-17 62.1 5.3 0.00063 20.3 0.0 7.4 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPE24817.1 - 1e-16 59.3 0.1 0.0032 17.1 0.1 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPE24817.1 - 2e-14 52.1 5.9 0.088 12.6 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.1 EPE24817.1 - 1.1e-11 44.2 1.7 0.013 15.3 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPE24817.1 - 8.9e-09 35.2 8.1 0.44 11.1 0.1 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPE24817.1 - 9.6e-08 31.6 0.4 4.8 7.6 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPE24817.1 - 0.00019 21.2 2.9 7.9 6.4 0.0 4.9 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 EPE24817.1 - 0.0084 15.1 3.2 17 4.3 0.0 4.6 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPE24817.1 - 0.0095 16.2 0.3 25 5.6 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.2 EPE24817.1 - 0.031 14.3 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat RPN7 PF10602.4 EPE24817.1 - 0.06 12.7 6.2 1.7 8.0 0.0 4.6 5 2 0 5 5 5 0 26S proteasome subunit RPN7 MIT PF04212.13 EPE24817.1 - 0.42 10.5 2.9 37 4.3 0.0 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF572 PF04502.8 EPE24818.1 - 1.5e-75 254.4 18.0 1.8e-75 254.2 12.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) SprT-like PF10263.4 EPE24818.1 - 0.38 10.4 2.7 0.9 9.1 1.8 1.6 1 1 0 1 1 1 0 SprT-like family zf-FCS PF06467.9 EPE24818.1 - 1.8 8.2 4.0 2.2 7.9 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF4407 PF14362.1 EPE24818.1 - 3.1 6.6 8.4 5.1 5.9 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TBCA PF02970.11 EPE24818.1 - 6.1 6.9 14.7 0.15 12.1 3.1 2.3 2 0 0 2 2 2 0 Tubulin binding cofactor A Transglut_i_TM PF14400.1 EPE24818.1 - 8.6 5.8 7.0 4.1 6.8 0.5 2.1 1 1 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices zf-C2H2 PF00096.21 EPE24819.1 - 2.1e-15 56.0 37.1 0.0013 18.9 0.9 6.3 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EPE24819.1 - 3.5e-15 55.6 30.0 4.4e-05 23.4 2.8 5.7 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EPE24819.1 - 1.9e-13 49.7 27.3 0.022 15.0 2.5 6.3 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.2 EPE24819.1 - 4.5e-11 42.5 25.2 1.3e-05 25.1 2.2 4.9 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EPE24819.1 - 2.5e-09 36.9 22.0 0.017 15.3 0.1 6.4 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 EPE24819.1 - 1.3e-07 31.3 30.6 0.0003 20.5 3.2 5.7 6 0 0 6 6 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EPE24819.1 - 1.2e-05 25.3 25.0 0.017 15.1 1.2 5.3 1 1 2 4 4 4 2 C2H2 type zinc-finger (2 copies) DUF1272 PF06906.6 EPE24819.1 - 0.02 14.6 1.2 0.02 14.6 0.8 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1272) zf-C2HC_2 PF13913.1 EPE24819.1 - 0.041 13.5 18.2 1.5 8.5 0.1 5.7 5 0 0 5 5 5 0 zinc-finger of a C2HC-type DUF1360 PF07098.6 EPE24819.1 - 0.077 12.7 0.1 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Rpr2 PF04032.11 EPE24819.1 - 0.13 12.1 6.0 1.9 8.4 0.1 2.9 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-Di19 PF05605.7 EPE24819.1 - 0.16 12.1 0.1 0.16 12.1 0.0 5.0 3 2 1 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.9 EPE24819.1 - 0.29 10.6 0.0 0.29 10.6 0.0 3.7 4 0 0 4 4 4 0 Rad50 zinc hook motif Zn-ribbon_8 PF09723.5 EPE24819.1 - 1.7 8.6 25.7 12 5.8 0.5 6.0 5 1 0 5 5 5 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 EPE24819.1 - 2.5 7.8 10.3 3.1 7.5 3.2 3.3 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.7 EPE24819.1 - 2.9 8.1 23.7 3.9 7.7 0.6 3.4 2 1 1 3 3 3 0 CHY zinc finger zf-AN1 PF01428.11 EPE24819.1 - 3.1 7.7 19.7 4 7.3 0.2 5.3 4 1 1 5 5 5 0 AN1-like Zinc finger AKAP95 PF04988.7 EPE24819.1 - 9.8 5.9 10.0 12 5.6 0.1 3.3 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) F-box-like PF12937.2 EPE24820.1 - 0.00055 19.6 1.3 0.0044 16.7 0.0 2.9 3 0 0 3 3 3 1 F-box-like F-box-like_2 PF13013.1 EPE24820.1 - 0.0055 16.4 0.1 0.0096 15.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like domain Lipase_GDSL PF00657.17 EPE24821.1 - 1e-14 54.9 1.1 2.1e-14 53.9 0.8 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EPE24821.1 - 5.8e-13 49.3 0.1 7.4e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE24822.1 - 4.7e-14 52.7 0.0 5.7e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Abhydrolase_2 PF02230.11 EPE24823.1 - 1.4e-08 34.4 0.3 2.1e-06 27.3 0.1 2.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EPE24823.1 - 0.0019 17.9 0.0 0.0029 17.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE24823.1 - 0.022 14.6 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE24823.1 - 0.048 12.8 0.2 0.1 11.7 0.1 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.4 EPE24823.1 - 0.059 12.6 0.7 0.37 9.9 0.2 2.4 1 1 1 2 2 2 0 Esterase PHB depolymerase MIP PF00230.15 EPE24824.1 - 1.8e-26 93.0 8.7 3.2e-26 92.2 6.0 1.4 1 1 0 1 1 1 1 Major intrinsic protein Fungal_trans PF04082.13 EPE24825.1 - 3.3e-17 62.2 0.2 1.1e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2417 PF10329.4 EPE24826.1 - 0.014 14.7 1.3 0.023 14.0 0.9 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Aminotran_5 PF00266.14 EPE24829.1 - 3.2e-12 45.8 0.0 8.2e-12 44.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPE24829.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.13 EPE24830.1 - 3.9e-148 493.3 0.0 4.4e-148 493.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Methyltransf_33 PF10017.4 EPE24831.1 - 0.052 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent COX7B PF05392.6 EPE24831.1 - 0.094 12.3 0.7 0.41 10.2 0.0 2.5 2 1 1 3 3 3 0 Cytochrome C oxidase chain VIIB WD40 PF00400.27 EPE24832.1 - 6.4e-34 114.6 7.4 1.7e-09 37.2 0.1 6.4 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EPE24832.1 - 1.1e-06 27.1 5.5 0.00024 19.4 0.3 4.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EPE24832.1 - 0.0047 16.6 0.0 0.054 13.2 0.0 2.6 1 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region YihI PF04220.7 EPE24833.1 - 0.32 10.3 4.3 0.37 10.0 3.0 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) WAP PF00095.16 EPE24833.1 - 2.5 8.1 12.6 4.2 7.4 8.7 1.4 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' EGF PF00008.22 EPE24833.1 - 2.9 7.9 11.0 6.5 6.8 7.6 1.6 1 0 0 1 1 1 0 EGF-like domain Nop14 PF04147.7 EPE24834.1 - 0.2 9.5 29.3 0.29 9.0 20.3 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 EPE24834.1 - 2.9 6.4 5.2 3.6 6.1 3.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Na_trans_assoc PF06512.8 EPE24834.1 - 7.5 6.4 17.4 11 5.9 12.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated NmrA PF05368.8 EPE24838.1 - 1.5e-60 204.3 0.0 1.9e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE24838.1 - 0.0046 16.9 0.3 1.7 8.6 0.0 2.3 2 0 0 2 2 2 2 NADH(P)-binding FAT PF02259.18 EPE24839.1 - 9.1e-76 255.1 3.6 9.1e-76 255.1 2.5 2.0 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 EPE24839.1 - 6.3e-29 101.1 0.5 4.2e-28 98.4 0.3 2.5 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EPE24839.1 - 9.4e-07 28.1 0.0 2.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 EPE24839.1 - 0.0011 18.5 6.7 0.39 10.4 1.1 4.1 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 EPE24839.1 - 0.0077 15.7 2.8 0.59 9.8 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPE24839.1 - 0.011 15.7 0.9 3.1 7.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPE24839.1 - 0.017 15.0 3.7 2.8 8.0 0.3 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPE24839.1 - 0.02 14.6 3.3 0.85 9.5 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1772 PF08592.6 EPE24840.1 - 3e-13 49.7 0.1 1.6e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) Sporozoite_P67 PF05642.6 EPE24843.1 - 0.35 8.6 10.1 0.44 8.3 7.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MGC-24 PF05283.6 EPE24843.1 - 1.7 8.3 16.5 0.22 11.3 8.3 1.8 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) CAP59_mtransfer PF11735.3 EPE24844.1 - 1.6e-63 214.1 0.0 2.1e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 NAS PF03059.11 EPE24845.1 - 3.7e-64 216.5 0.1 4.7e-64 216.2 0.1 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.1 EPE24845.1 - 6.8e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.19 EPE24847.1 - 2e-40 138.7 23.8 9.9e-23 80.4 6.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPE24847.1 - 1.2e-21 76.8 30.8 7.7e-14 51.1 14.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EPE24848.1 - 1.7e-17 63.1 0.1 2.8e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EPE24849.1 - 4.7e-12 46.1 0.2 7.6e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE24849.1 - 1.2e-06 28.3 0.3 2.3e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE24849.1 - 0.00088 19.1 0.0 0.003 17.3 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase BCS1_N PF08740.6 EPE24851.1 - 1.8e-39 135.2 0.0 2.7e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EPE24851.1 - 8.7e-16 58.3 0.0 1.9e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EPE24851.1 - 0.00084 18.7 0.0 0.0023 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPE24851.1 - 0.0022 17.1 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EPE24851.1 - 0.0028 18.4 0.0 0.0093 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPE24851.1 - 0.0094 16.2 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPE24851.1 - 0.011 15.4 0.0 0.2 11.4 0.0 2.9 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EPE24851.1 - 0.02 14.4 0.4 0.043 13.3 0.3 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EPE24851.1 - 0.027 13.5 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 EPE24851.1 - 0.041 13.8 0.2 0.26 11.2 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 EPE24851.1 - 0.059 12.7 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 EPE24851.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EPE24851.1 - 0.22 10.9 0.8 6.4 6.1 0.0 2.6 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) Syntaxin-6_N PF09177.6 EPE24852.1 - 2e-23 82.6 2.1 3.1e-23 81.9 0.2 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EPE24852.1 - 1.1e-08 34.6 6.5 4.9e-08 32.5 1.1 2.6 2 0 0 2 2 2 1 SNARE domain Transposase_22 PF02994.9 EPE24852.1 - 0.024 13.1 0.7 0.056 11.9 0.0 1.7 2 0 0 2 2 2 0 L1 transposable element WXG100 PF06013.7 EPE24852.1 - 0.043 13.8 3.0 3.6 7.6 0.0 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF2203 PF09969.4 EPE24852.1 - 0.05 13.8 0.4 0.86 9.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF972 PF06156.8 EPE24852.1 - 0.068 13.5 0.4 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 EPE24852.1 - 0.1 12.6 0.9 20 5.2 0.1 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EPE24852.1 - 0.13 11.8 4.7 0.35 10.4 3.3 1.7 1 1 0 1 1 1 0 IncA protein DUF948 PF06103.6 EPE24852.1 - 0.14 12.0 2.9 0.7 9.7 0.3 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TBPIP PF07106.8 EPE24852.1 - 0.53 9.8 3.2 2.1 7.8 0.1 2.4 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Methyltransf_32 PF13679.1 EPE24853.1 - 9e-18 64.3 0.1 2.2e-17 63.0 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Sof1 PF04158.9 EPE24853.1 - 0.32 11.0 3.0 0.23 11.5 0.5 1.8 2 0 0 2 2 2 0 Sof1-like domain Pentapeptide_4 PF13599.1 EPE24855.1 - 1.7e-11 43.7 2.2 0.00035 20.3 1.2 4.4 2 1 1 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EPE24855.1 - 0.0031 17.3 4.0 1.3 9.0 0.0 4.3 5 0 0 5 5 5 2 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 EPE24856.1 - 2e-09 37.0 5.1 0.0021 17.8 3.4 4.0 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EPE24856.1 - 0.0011 18.8 1.9 2 8.3 0.0 3.8 4 0 0 4 4 4 2 Pentapeptide repeats (9 copies) Acetyltransf_7 PF13508.1 EPE24857.1 - 2.6e-06 27.4 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE24857.1 - 8.4e-06 25.7 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE24857.1 - 0.00036 20.6 0.0 0.00049 20.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE24857.1 - 0.027 14.2 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein FAD_binding_4 PF01565.18 EPE24859.1 - 1.9e-16 59.7 1.3 4.2e-16 58.6 0.9 1.6 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE24859.1 - 9.8e-12 44.5 0.1 2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EPE24859.1 - 0.05 12.7 0.1 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Peptidase_A4 PF01828.12 EPE24860.1 - 8.8e-20 70.6 0.2 1.3e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase A4 family WD40 PF00400.27 EPE24862.1 - 5.8e-25 86.2 14.7 7.4e-07 28.8 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Fungal_trans PF04082.13 EPE24863.1 - 9.6e-27 93.4 1.3 1.7e-26 92.6 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE24863.1 - 6.6e-07 29.1 8.6 6.6e-07 29.1 5.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2967 PF11179.3 EPE24864.1 - 0.051 13.0 0.2 0.055 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) MMR_HSR1 PF01926.18 EPE24866.1 - 3.2e-07 30.3 0.0 4.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPE24866.1 - 1.3e-05 24.4 0.0 2.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPE24866.1 - 6.2e-05 23.0 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 EPE24866.1 - 0.00027 20.8 0.8 0.54 10.0 0.0 2.2 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 EPE24866.1 - 0.00088 18.4 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.1 EPE24866.1 - 0.00096 19.3 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EPE24866.1 - 0.0012 18.1 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EPE24866.1 - 0.0062 17.0 0.0 0.01 16.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 EPE24866.1 - 0.0073 15.1 0.1 0.013 14.2 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Arch_ATPase PF01637.13 EPE24866.1 - 0.026 14.2 0.1 0.061 13.0 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 EPE24866.1 - 0.053 14.3 0.2 0.11 13.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPE24866.1 - 0.081 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EPE24867.1 - 1e-08 35.1 0.1 1.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPE24867.1 - 0.0003 20.0 0.1 0.00057 19.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EPE24867.1 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 Septin ABC_tran PF00005.22 EPE24867.1 - 0.0013 18.9 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AIG1 PF04548.11 EPE24867.1 - 0.0017 17.4 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 EPE24867.1 - 0.002 17.3 0.1 0.0039 16.4 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EPE24867.1 - 0.0031 17.3 6.0 0.12 12.1 0.0 2.7 2 1 1 3 3 3 2 Dynamin family Miro PF08477.8 EPE24867.1 - 0.0063 17.0 0.4 0.021 15.3 0.3 1.9 1 1 0 1 1 1 1 Miro-like protein GATase_5 PF13507.1 EPE24868.1 - 1.7e-97 325.3 0.0 2.7e-97 324.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EPE24868.1 - 3.3e-41 140.8 0.1 1.1e-20 74.2 0.0 3.0 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EPE24868.1 - 8.6e-24 83.6 0.1 3.9e-23 81.4 0.0 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain PQ-loop PF04193.9 EPE24869.1 - 7.1e-15 54.3 1.0 1.8e-14 53.0 0.7 1.7 1 0 0 1 1 1 1 PQ loop repeat ORC6 PF05460.8 EPE24869.1 - 0.73 8.8 6.9 1.2 8.2 4.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HATPase_c PF02518.21 EPE24872.1 - 1e-22 79.9 0.1 1.9e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE24872.1 - 4.8e-17 61.9 4.8 6.3e-17 61.6 0.1 3.3 3 1 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 EPE24872.1 - 8.8e-09 35.2 1.2 3.2e-08 33.4 0.2 2.6 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EPE24872.1 - 1.4e-05 25.3 0.0 0.014 15.7 0.0 2.8 2 0 0 2 2 2 2 PAS domain GAF_2 PF13185.1 EPE24872.1 - 0.061 13.8 0.0 0.31 11.5 0.0 2.2 2 0 0 2 2 2 0 GAF domain PUB PF09409.5 EPE24872.1 - 0.082 12.6 0.3 0.22 11.2 0.2 1.6 1 0 0 1 1 1 0 PUB domain B56 PF01603.15 EPE24873.1 - 2.9e-173 576.1 7.4 3.5e-173 575.9 5.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Tau95 PF09734.4 EPE24874.1 - 4e-58 197.1 0.1 5.1e-58 196.8 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Ifi-6-16 PF06140.8 EPE24875.1 - 0.0051 16.5 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 Interferon-induced 6-16 family HET PF06985.6 EPE24876.1 - 5.5e-28 97.8 0.0 8.6e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 EPE24878.1 - 1.7e-22 80.0 0.0 1.1e-21 77.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EPE24878.1 - 1.4e-06 28.1 0.5 3.3e-06 27.0 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE24878.1 - 0.00019 20.3 3.5 0.0093 14.8 2.9 2.2 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EPE24878.1 - 0.00078 19.5 0.1 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EPE24878.1 - 0.001 17.7 0.1 0.0016 17.1 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.2 EPE24878.1 - 0.004 16.2 0.1 0.008 15.3 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPE24878.1 - 0.0088 15.9 0.9 0.026 14.4 0.6 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE24878.1 - 0.0098 14.8 2.2 0.041 12.7 1.6 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPE24878.1 - 0.025 13.6 0.5 0.054 12.5 0.1 1.6 2 0 0 2 2 2 0 Thi4 family SE PF08491.5 EPE24878.1 - 0.026 13.3 0.0 0.12 11.2 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase ThiF PF00899.16 EPE24878.1 - 0.029 14.2 0.7 0.081 12.7 0.1 2.0 2 0 0 2 2 2 0 ThiF family Pyr_redox PF00070.22 EPE24878.1 - 0.032 14.6 0.4 0.64 10.4 0.2 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPE24878.1 - 0.23 10.2 1.6 0.36 9.6 1.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Spc97_Spc98 PF04130.8 EPE24879.1 - 1.1e-73 248.3 7.9 1.7e-73 247.8 5.5 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EPE24879.1 - 5.4e-07 28.1 0.5 9.2e-06 24.0 0.4 2.1 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 SseB_C PF14581.1 EPE24879.1 - 0.02 14.7 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 SseB protein C-terminal domain Glyco_transf_15 PF01793.11 EPE24880.1 - 4.1e-130 433.5 6.2 4.7e-130 433.3 4.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Beta-lactamase PF00144.19 EPE24881.1 - 5.7e-36 124.1 0.0 8.5e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase MoeZ_MoeB PF05237.8 EPE24881.1 - 0.16 11.6 0.0 0.66 9.6 0.0 2.0 1 1 1 2 2 2 0 MoeZ/MoeB domain MTHFR PF02219.12 EPE24882.1 - 1.3e-104 349.2 0.0 2.1e-104 348.6 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Aminotran_1_2 PF00155.16 EPE24883.1 - 7.5e-08 31.7 0.0 6.5e-07 28.6 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II CbiA PF01656.18 EPE24883.1 - 0.038 13.3 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DLH PF01738.13 EPE24884.1 - 2.9e-17 62.6 0.0 9.3e-17 61.0 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPE24884.1 - 4.6e-06 26.4 0.0 6.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EPE24884.1 - 0.077 12.6 0.0 1.1 8.9 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Taeniidae_ag PF05596.6 EPE24884.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Taeniidae antigen MIP PF00230.15 EPE24887.1 - 3.4e-39 134.6 18.7 4.3e-39 134.2 13.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein UPF0444 PF15475.1 EPE24887.1 - 0.041 13.9 2.3 0.12 12.3 1.6 1.8 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 adh_short PF00106.20 EPE24888.1 - 1.8e-10 40.9 0.1 1.1e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE24888.1 - 0.0006 19.5 0.0 0.00093 18.9 0.0 1.4 1 1 0 1 1 1 1 KR domain Corona_NS2A PF05213.7 EPE24888.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NS2A protein Pkinase PF00069.20 EPE24889.1 - 2.5e-20 72.7 0.0 3e-19 69.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE24889.1 - 1.3e-09 37.5 0.0 8.6e-09 34.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase MoaF PF10703.4 EPE24889.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F wnt PF00110.14 EPE24890.1 - 0.0031 16.7 0.9 0.036 13.2 0.5 2.0 2 0 0 2 2 2 1 wnt family PhoQ_Sensor PF08918.5 EPE24890.1 - 0.077 12.4 0.8 0.17 11.4 0.5 1.5 1 0 0 1 1 1 0 PhoQ Sensor Pkinase PF00069.20 EPE24891.1 - 9.5e-24 83.9 0.0 1.6e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE24891.1 - 2.7e-12 46.3 0.0 6.1e-12 45.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase HNH_2 PF13391.1 EPE24892.1 - 2e-11 43.5 0.0 4.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease ORC6 PF05460.8 EPE24892.1 - 0.081 12.0 1.4 0.13 11.3 0.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HSP20 PF00011.16 EPE24893.1 - 1e-20 73.4 0.1 1.3e-14 53.9 0.1 2.3 2 1 0 2 2 2 2 Hsp20/alpha crystallin family DUF221 PF02714.10 EPE24894.1 - 1.7e-92 309.7 18.7 1.9e-92 309.6 12.3 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPE24894.1 - 9.8e-34 116.1 1.4 1.3e-33 115.8 0.0 1.9 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EPE24894.1 - 1.2e-18 67.4 0.5 2.6e-18 66.3 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) PGM_PMM_I PF02878.11 EPE24895.1 - 7e-31 106.5 0.0 1e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EPE24895.1 - 2.2e-24 85.6 0.0 5.9e-24 84.2 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EPE24895.1 - 3.7e-15 56.1 0.0 7.9e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EPE24895.1 - 6.1e-12 45.3 0.0 1.4e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 EPE24896.1 - 9.6e-24 84.5 0.1 1.1e-23 84.3 0.1 1.0 1 0 0 1 1 1 1 Exonuclease ATP_sub_h PF10775.4 EPE24897.1 - 9e-27 92.5 0.6 1.4e-26 92.0 0.4 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EPE24897.1 - 0.034 14.0 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Lipase_GDSL PF00657.17 EPE24898.1 - 4.7e-15 56.0 0.1 6.2e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EPE24898.1 - 1.3e-12 48.2 0.0 1.7e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FYVE PF01363.16 EPE24900.1 - 0.0025 17.6 0.6 0.0025 17.6 0.4 2.3 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.11 EPE24900.1 - 2.6 7.9 9.5 0.94 9.3 0.9 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger HET PF06985.6 EPE24901.1 - 2.4e-20 73.1 0.0 4.5e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MaoC_dehydratas PF01575.14 EPE24902.1 - 4.1e-20 71.3 0.0 6.7e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EPE24902.1 - 5e-07 29.5 0.0 8.4e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase DUF1768 PF08719.6 EPE24903.1 - 1.4e-45 154.8 0.0 1.7e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) TFIIB PF00382.14 EPE24904.1 - 4.4e-36 122.5 0.1 1.9e-21 75.6 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EPE24904.1 - 4.2e-13 48.3 0.7 9.4e-13 47.2 0.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 EPE24904.1 - 0.00016 21.6 0.0 0.2 11.5 0.0 2.5 1 1 1 2 2 2 2 Cyclin, C-terminal domain Qn_am_d_aII PF14930.1 EPE24904.1 - 0.092 12.7 0.0 0.83 9.6 0.0 2.3 1 1 1 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II RB_B PF01857.15 EPE24904.1 - 0.16 11.4 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain AAA PF00004.24 EPE24905.1 - 4.4e-40 136.9 0.0 8.6e-40 135.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPE24905.1 - 0.00017 21.3 0.1 0.00088 19.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPE24905.1 - 0.00022 21.2 0.5 0.012 15.5 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EPE24905.1 - 0.00024 20.2 0.0 0.0005 19.1 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EPE24905.1 - 0.00088 19.4 1.2 0.018 15.1 0.0 2.8 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.9 EPE24905.1 - 0.00089 19.2 0.1 0.0095 15.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EPE24905.1 - 0.0046 16.2 0.2 0.045 12.9 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EPE24905.1 - 0.0066 15.6 0.1 0.017 14.2 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EPE24905.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EPE24905.1 - 0.011 14.7 0.0 0.023 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EPE24905.1 - 0.018 14.7 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EPE24905.1 - 0.024 14.0 0.1 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EPE24905.1 - 0.039 13.3 1.2 0.35 10.2 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EPE24905.1 - 0.049 13.2 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPE24905.1 - 0.097 13.4 0.1 0.097 13.4 0.1 3.0 2 2 1 3 3 3 0 AAA domain AAA_11 PF13086.1 EPE24905.1 - 0.33 10.4 2.2 0.83 9.1 0.0 2.5 2 2 0 3 3 3 0 AAA domain Vfa1 PF08432.5 EPE24905.1 - 3.4 7.6 9.2 6.5 6.7 6.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pro-kuma_activ PF09286.6 EPE24906.1 - 2.3e-46 157.4 0.0 3.6e-45 153.5 0.0 2.5 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EPE24906.1 - 8e-07 28.4 0.3 1.3e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 Subtilase family ADH_zinc_N PF00107.21 EPE24907.1 - 6.4e-13 48.3 0.0 1.5e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE24907.1 - 9.5e-10 38.2 0.0 8.9e-09 35.0 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain F-box-like PF12937.2 EPE24908.1 - 0.0001 21.9 0.1 0.00021 20.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE24908.1 - 0.011 15.4 0.3 0.02 14.5 0.2 1.4 1 0 0 1 1 1 0 F-box domain PBP1_TM PF14812.1 EPE24909.1 - 9.2 6.6 16.5 6.7 7.0 3.0 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 EPE24912.1 - 1.9e-25 89.3 42.3 3.6e-24 85.1 29.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE24912.1 - 1.1e-20 73.3 14.7 1.5e-20 72.9 10.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RNase_T PF00929.19 EPE24913.1 - 1.5e-18 67.6 0.1 1.5e-18 67.6 0.0 1.7 2 0 0 2 2 2 1 Exonuclease zf-C2H2 PF00096.21 EPE24913.1 - 0.0065 16.7 0.4 0.023 15.0 0.3 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPE24913.1 - 0.036 13.9 0.2 0.1 12.5 0.0 1.9 1 1 1 2 2 2 0 C2H2-type zinc finger Tetraspannin PF00335.15 EPE24913.1 - 6 6.0 5.1 13 4.9 3.5 1.5 1 0 0 1 1 1 0 Tetraspanin family Acyl_transf_3 PF01757.17 EPE24914.1 - 6.7e-32 110.6 36.2 8.6e-32 110.2 25.1 1.1 1 0 0 1 1 1 1 Acyltransferase family ABC2_membrane_2 PF12679.2 EPE24914.1 - 0.057 12.2 1.1 0.12 11.2 0.8 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein eIF3g PF12353.3 EPE24915.1 - 0.00023 21.0 36.8 0.0038 17.1 1.4 4.4 2 1 1 4 4 4 3 Eukaryotic translation initiation factor 3 subunit G Pex14_N PF04695.8 EPE24915.1 - 3.9 7.5 6.8 7.6 6.5 4.7 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dicty_REP PF05086.7 EPE24915.1 - 6.9 4.2 11.4 9.1 3.8 7.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein p450 PF00067.17 EPE24916.1 - 1.3e-31 109.6 0.1 3.9e-30 104.7 0.1 2.3 1 1 0 1 1 1 1 Cytochrome P450 Acylphosphatase PF00708.13 EPE24917.1 - 0.92 9.6 3.1 6.1 7.0 0.2 3.0 2 1 1 3 3 3 0 Acylphosphatase F-box-like PF12937.2 EPE24918.1 - 2.9e-09 36.5 0.8 8.1e-09 35.0 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPE24918.1 - 5.7e-05 22.6 4.9 0.034 13.8 0.5 4.1 4 0 0 4 4 4 2 F-box domain MFS_1 PF07690.11 EPE24922.1 - 5.7e-28 97.6 35.9 5.7e-28 97.6 24.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PLDc_N PF13396.1 EPE24923.1 - 3.1e-11 42.7 1.6 3.9e-11 42.4 0.8 1.4 1 1 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF3309 PF11752.3 EPE24923.1 - 0.0035 17.0 1.8 0.0037 17.0 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3309) DUF456 PF04306.8 EPE24923.1 - 0.037 14.0 0.6 0.048 13.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF3951 PF13131.1 EPE24923.1 - 0.044 13.5 1.7 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) DUF4199 PF13858.1 EPE24923.1 - 0.099 12.5 0.3 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) FUSC-like PF12805.2 EPE24923.1 - 0.11 11.4 1.5 0.12 11.2 1.0 1.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Cation_ATPase_C PF00689.16 EPE24923.1 - 0.32 10.5 2.3 0.37 10.2 1.6 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus AMP-binding PF00501.23 EPE24924.1 - 4.2e-95 318.5 0.0 4.9e-95 318.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE24924.1 - 5.7e-13 49.6 1.4 2e-12 47.8 0.5 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain IBR PF01485.16 EPE24925.1 - 8.5e-13 47.9 18.6 2.8e-08 33.4 2.3 3.8 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EPE24925.1 - 0.0026 17.5 10.0 0.0026 17.5 6.9 3.5 2 1 1 3 3 3 1 Ring finger domain ESCRT-II PF05871.7 EPE24926.1 - 0.043 13.7 0.1 0.063 13.2 0.1 1.2 1 0 0 1 1 1 0 ESCRT-II complex subunit DZR PF12773.2 EPE24926.1 - 0.11 12.2 5.0 0.35 10.7 1.6 2.8 2 1 0 2 2 2 0 Double zinc ribbon Paired_CXXCH_1 PF09699.5 EPE24926.1 - 0.45 10.0 5.7 0.37 10.3 0.2 3.1 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_c3_2 PF14537.1 EPE24926.1 - 1.6 9.1 9.1 0.27 11.6 0.3 2.6 2 1 0 2 2 2 0 Cytochrome c3 DUF2387 PF09526.5 EPE24926.1 - 4.6 7.2 11.8 20 5.1 2.6 3.8 2 2 1 3 3 3 0 Probable metal-binding protein (DUF2387) Amidase PF01425.16 EPE24927.1 - 5.1e-35 121.1 2.0 9.1e-34 117.0 0.4 2.2 2 0 0 2 2 2 2 Amidase DFP PF04127.10 EPE24928.1 - 5.7e-13 48.8 0.0 5e-05 22.9 0.0 3.2 2 1 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein HAD PF12710.2 EPE24928.1 - 0.094 12.8 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EPE24930.1 - 5.6e-26 90.9 0.5 1.1e-25 90.0 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE24930.1 - 1.3e-05 24.9 8.7 2.8e-05 23.9 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.8 EPE24930.1 - 0.55 10.0 8.8 0.029 14.2 1.5 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CENP-O PF09496.5 EPE24931.1 - 5.6e-22 77.7 0.0 1.1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component FliJ PF02050.11 EPE24931.1 - 0.011 15.7 0.5 0.15 12.1 0.2 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein AIP3 PF03915.8 EPE24931.1 - 0.11 11.4 0.2 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Uds1 PF15456.1 EPE24931.1 - 0.93 9.4 4.0 0.63 10.0 0.3 2.1 2 0 0 2 2 2 0 Up-regulated During Septation Acatn PF13000.2 EPE24932.1 - 5.4e-154 513.7 25.5 1.3e-78 264.9 7.5 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 TFIIF_alpha PF05793.7 EPE24932.1 - 0.21 9.9 7.6 0.31 9.3 5.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) EzrA PF06160.7 EPE24933.1 - 0.031 12.4 0.1 0.047 11.8 0.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA YchF-GTPase_C PF06071.8 EPE24934.1 - 2.3e-32 110.6 0.2 5.4e-32 109.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EPE24934.1 - 8e-14 51.5 0.0 2e-13 50.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE24934.1 - 0.0013 18.0 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EPE24934.1 - 0.0074 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain MobB PF03205.9 EPE24934.1 - 0.047 13.3 0.4 3.6 7.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EPE24934.1 - 0.065 13.0 0.0 1.1 9.0 0.0 2.4 1 1 0 2 2 2 0 Dynamin family AAA_23 PF13476.1 EPE24934.1 - 0.28 11.4 3.9 1.7 8.8 2.7 2.5 1 1 0 1 1 1 0 AAA domain Peptidase_C97 PF05903.9 EPE24935.1 - 2.2e-32 111.9 0.0 3e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EPE24935.1 - 1.8e-05 24.6 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF3742 PF12553.3 EPE24935.1 - 0.33 11.4 3.2 0.7 10.3 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3742) Ribosomal_S11 PF00411.14 EPE24936.1 - 1.8e-12 47.3 0.1 4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 PAP1 PF08601.5 EPE24936.1 - 0.05 13.2 1.0 0.059 13.0 0.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Tim44 PF04280.10 EPE24937.1 - 1.1e-32 112.9 0.0 2.4e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 Tim44-like domain Polysacc_deac_1 PF01522.16 EPE24938.1 - 5e-22 77.8 0.0 1.1e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EPE24938.1 - 0.048 13.0 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) VPS9 PF02204.13 EPE24939.1 - 2.5e-17 62.7 0.0 8.3e-17 61.1 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 EPE24939.1 - 4.2e-16 58.5 0.0 4.1e-11 42.7 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPE24939.1 - 4.3e-11 42.9 0.0 5.4e-07 29.8 0.0 3.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE24939.1 - 2.1e-09 37.6 0.2 0.0024 18.3 0.0 4.8 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE24939.1 - 3.8e-08 32.7 0.0 1.9 8.9 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 EPE24939.1 - 1.2e-06 28.0 0.4 0.018 14.8 0.0 4.8 6 0 0 6 6 6 1 Ankyrin repeat PX PF00787.19 EPE24939.1 - 0.04 13.6 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 PX domain PUA PF01472.15 EPE24940.1 - 2.7e-14 52.6 0.7 1.8e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 PUA domain RE_HaeIII PF09556.5 EPE24940.1 - 0.044 12.6 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 HaeIII restriction endonuclease DUF1479 PF07350.7 EPE24940.1 - 0.049 12.1 0.0 0.062 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Abhydrolase_3 PF07859.8 EPE24941.1 - 4.8e-26 91.6 0.0 6.7e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EPE24941.1 - 4.9e-12 45.1 0.0 1.4e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPE24941.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EPE24941.1 - 0.19 10.3 0.5 0.41 9.2 0.3 1.5 1 1 0 1 1 1 0 Carboxylesterase family TPR_11 PF13414.1 EPE24942.1 - 3.8e-18 64.8 3.0 4.6e-15 55.0 0.4 2.4 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EPE24942.1 - 1.3e-13 49.7 2.1 0.00012 21.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPE24942.1 - 1.1e-12 46.9 0.8 8.2e-05 22.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPE24942.1 - 4.1e-09 36.8 13.7 1.7e-07 31.6 0.9 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPE24942.1 - 1e-06 28.4 2.9 0.035 14.2 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPE24942.1 - 1.1e-05 25.5 2.6 0.015 15.8 0.5 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPE24942.1 - 2.3e-05 23.8 0.4 1.1 9.2 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPE24942.1 - 0.00023 21.0 2.0 0.52 10.2 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPE24942.1 - 0.0011 19.2 0.2 0.0036 17.5 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE24942.1 - 0.0014 18.3 0.1 4 7.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 EPE24942.1 - 0.0069 16.7 0.4 1.2 9.3 0.3 2.2 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_9 PF13371.1 EPE24942.1 - 0.0074 16.1 0.3 0.023 14.5 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat Turandot PF07240.6 EPE24942.1 - 0.018 14.5 0.0 7.6 6.1 0.0 3.1 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot XPC-binding PF09280.6 EPE24942.1 - 0.086 12.3 5.6 0.036 13.5 1.5 2.0 2 0 0 2 2 2 0 XPC-binding domain ABC_tran PF00005.22 EPE24943.1 - 2e-35 122.0 0.5 4.2e-35 121.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EPE24943.1 - 1.2e-16 60.9 5.1 1.2e-16 60.9 3.5 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EPE24943.1 - 1.3e-05 24.5 0.0 0.00016 21.0 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE24943.1 - 0.00027 21.0 0.2 0.013 15.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPE24943.1 - 0.0071 15.5 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPE24943.1 - 0.011 15.1 0.5 0.034 13.6 0.4 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 EPE24943.1 - 0.032 14.1 0.2 0.19 11.6 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NfeD PF01957.13 EPE24943.1 - 0.036 14.1 0.3 0.37 10.9 0.0 2.7 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding PAM2 PF07145.10 EPE24943.1 - 0.09 12.3 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region AAA_23 PF13476.1 EPE24943.1 - 1.6 9.0 10.7 0.7 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cep57_CLD PF14073.1 EPE24944.1 - 0.49 10.2 36.8 0.89 9.3 15.0 2.7 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 Pox_A_type_inc PF04508.7 EPE24944.1 - 1.4 8.8 8.1 3.1 7.8 0.5 4.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat M_domain PF12938.2 EPE24944.1 - 1.8 8.3 4.0 9.4 5.9 0.4 2.5 2 1 0 2 2 2 0 M domain of GW182 Cyt-b5 PF00173.23 EPE24946.1 - 2.3e-14 52.9 0.0 2.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Inositol_P PF00459.20 EPE24947.1 - 1.2e-70 237.9 0.0 1.3e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family AP_endonuc_2 PF01261.19 EPE24948.1 - 2.1e-26 92.5 0.0 8.6e-26 90.5 0.0 1.8 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel Shikimate_dh_N PF08501.6 EPE24949.1 - 6.3e-22 77.4 0.0 1.1e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EPE24949.1 - 1.8e-13 50.7 0.0 2.7e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EPE24949.1 - 0.04 12.9 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pro_CA PF00484.14 EPE24950.1 - 1.4e-20 73.8 0.0 1.7e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Sugar_tr PF00083.19 EPE24951.1 - 8.6e-133 443.2 28.3 9.9e-133 443.0 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE24951.1 - 7.2e-24 84.1 31.8 7.2e-24 84.1 22.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Pribosyltran_N PF13793.1 EPE24952.1 - 6.1e-39 132.3 0.1 4e-38 129.7 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EPE24952.1 - 3.9e-32 111.4 0.0 7.5e-28 97.5 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EPE24952.1 - 9.2e-06 25.3 0.1 0.00025 20.7 0.0 2.7 3 0 0 3 3 3 1 Phosphoribosyl transferase domain XPG_I_2 PF12813.2 EPE24953.1 - 9.6e-54 182.4 0.0 1.7e-53 181.6 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing K_trans PF02705.11 EPE24954.1 - 6e-181 602.4 13.6 7.1e-181 602.1 9.4 1.0 1 0 0 1 1 1 1 K+ potassium transporter Sugar_tr PF00083.19 EPE24955.1 - 1.3e-78 264.6 23.0 1.5e-78 264.4 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE24955.1 - 1.5e-19 69.9 49.4 1.4e-15 56.8 13.6 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EPE24955.1 - 0.0016 18.3 7.0 0.54 10.3 0.6 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF1228) Gly-zipper_YMGG PF13441.1 EPE24955.1 - 0.18 11.3 5.3 0.62 9.6 3.7 1.9 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 EPE24955.1 - 0.44 10.2 9.1 1.7 8.3 6.3 2.1 1 0 0 1 1 1 0 Glycine zipper 2TM domain DegT_DnrJ_EryC1 PF01041.12 EPE24960.1 - 4.9e-79 265.9 0.0 5.9e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EPE24960.1 - 2.9e-08 33.0 0.2 9.1e-08 31.4 0.1 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPE24960.1 - 5.7e-08 31.8 0.2 8.8e-08 31.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 EPE24960.1 - 4.5e-06 25.4 0.5 1.1e-05 24.2 0.4 1.5 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.15 EPE24960.1 - 0.00061 18.1 0.2 0.00081 17.7 0.2 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.11 EPE24961.1 - 3.3e-40 137.8 31.2 3.3e-40 137.8 21.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE24961.1 - 1.9e-15 56.4 23.9 5.6e-15 54.8 16.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EPE24961.1 - 0.035 12.1 6.8 0.01 13.9 1.3 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Bac_luciferase PF00296.15 EPE24962.1 - 5.8e-53 180.0 0.0 1.1e-52 179.0 0.0 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase Fungal_trans PF04082.13 EPE24963.1 - 2.5e-29 101.9 0.3 3.8e-29 101.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE24963.1 - 7.5e-10 38.5 9.5 1.3e-09 37.8 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 EPE24965.1 - 6.7e-63 212.7 35.3 7.9e-63 212.5 24.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Bac_luciferase PF00296.15 EPE24966.1 - 1.2e-57 195.4 0.1 1.6e-57 195.0 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Arch_ATPase PF01637.13 EPE24970.1 - 0.00014 21.6 0.1 0.0002 21.1 0.1 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EPE24970.1 - 0.00094 19.2 4.6 0.021 14.8 2.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EPE24970.1 - 0.0046 16.3 0.0 0.015 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPE24970.1 - 0.0056 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 EPE24970.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EPE24970.1 - 0.028 14.5 0.2 0.08 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.26 EPE24972.1 - 1.2e-12 47.6 6.3 3.7e-07 30.0 0.2 4.1 4 1 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPE24972.1 - 1.3e-10 41.2 21.2 2e-09 37.4 2.8 4.0 3 1 1 4 4 4 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EPE24972.1 - 5.8 7.1 12.7 3 8.0 0.1 4.4 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MFS_1 PF07690.11 EPE24973.1 - 9.6e-32 110.0 40.3 5.4e-31 107.5 28.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily ADH_zinc_N PF00107.21 EPE24973.1 - 1.3e-25 89.4 0.0 2.7e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE24973.1 - 8.8e-05 23.3 0.0 0.00023 22.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF912 PF06024.7 EPE24973.1 - 0.035 14.1 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ELFV_dehydrog PF00208.16 EPE24973.1 - 0.086 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AA_permease PF00324.16 EPE24974.1 - 1.7e-137 458.6 49.5 2.1e-137 458.3 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE24974.1 - 1.7e-31 109.2 56.2 2.1e-31 108.9 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease RGCC PF15151.1 EPE24975.1 - 0.14 12.6 0.4 0.14 12.6 0.3 2.1 1 1 0 2 2 2 0 Response gene to complement 32 protein family EI24 PF07264.6 EPE24977.1 - 0.037 13.4 20.5 0.38 10.1 14.2 2.3 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) PAP1 PF08601.5 EPE24978.1 - 0.7 9.5 8.2 1 8.9 5.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Mid2 PF04478.7 EPE24979.1 - 8.5e-05 22.0 0.1 0.00018 20.9 0.1 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF1191 PF06697.7 EPE24979.1 - 0.025 13.4 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Beta-APP PF03494.8 EPE24979.1 - 0.33 10.4 4.0 0.78 9.2 1.7 2.2 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) Gly-zipper_Omp PF13488.1 EPE24979.1 - 3.5 7.3 9.2 0.46 10.1 3.6 1.6 2 0 0 2 2 2 0 Glycine zipper Pkinase PF00069.20 EPE24981.1 - 8.2e-68 228.3 0.0 1e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE24981.1 - 1.8e-28 99.3 0.0 2.4e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE24981.1 - 1.6e-06 27.2 0.0 2.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPE24981.1 - 0.00018 21.3 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPE24981.1 - 0.0006 18.9 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPE24981.1 - 0.032 13.5 0.0 0.071 12.4 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PAP2 PF01569.16 EPE24982.1 - 1.4e-12 47.3 4.3 1.4e-12 47.3 2.9 2.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EPE24982.1 - 1.4e-06 28.0 8.7 1.4e-06 28.0 6.0 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EPE24982.1 - 4.3 7.6 9.8 0.5 10.6 1.8 2.6 3 0 0 3 3 3 0 PAP2 superfamily C-terminal MFS_1 PF07690.11 EPE24983.1 - 3.8e-22 78.4 64.1 1.9e-13 49.8 23.7 3.1 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EPE24983.1 - 6.5e-09 34.5 30.0 9.3e-09 34.0 20.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trehalase PF01204.13 EPE24983.1 - 0.029 13.0 0.1 0.048 12.3 0.1 1.2 1 0 0 1 1 1 0 Trehalase Zn_clus PF00172.13 EPE24984.1 - 7.2e-06 25.8 13.0 1.3e-05 25.0 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE24984.1 - 0.0019 16.8 0.7 0.0025 16.4 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 EPE24985.1 - 5.5e-27 93.9 0.7 9.2e-27 93.2 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE24985.1 - 0.00034 20.4 0.0 0.00077 19.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_5 PF00941.16 EPE24985.1 - 0.021 14.2 0.1 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase Zn_clus PF00172.13 EPE24988.1 - 1.8e-06 27.7 7.5 2.9e-06 27.0 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE24988.1 - 1e-05 24.3 0.1 1.8e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EPE24989.1 - 5.5e-18 65.6 0.5 7.2e-18 65.2 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE24989.1 - 8.4e-07 28.8 0.0 1.7e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.9 EPE24990.1 - 4e-44 151.0 0.1 7.3e-44 150.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EPE24990.1 - 8.7e-11 41.2 9.0 8.7e-11 41.2 6.2 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain phage_tail_N PF08400.5 EPE24991.1 - 0.16 11.6 5.5 0.53 9.9 0.7 2.4 2 0 0 2 2 2 0 Prophage tail fibre N-terminal MFS_1 PF07690.11 EPE24992.1 - 1.4e-39 135.8 44.1 6.5e-37 127.0 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE24992.1 - 5.4e-11 41.7 26.8 8.6e-10 37.7 8.4 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.15 EPE24992.1 - 0.016 13.2 3.3 0.68 7.9 0.7 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Isochorismatase PF00857.15 EPE24993.1 - 9e-25 87.6 0.0 1.2e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Cro PF09048.5 EPE24993.1 - 0.037 13.6 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Cro HK PF02110.10 EPE24994.1 - 3e-77 259.1 3.4 4.9e-77 258.4 2.4 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EPE24994.1 - 7.3e-57 191.3 2.1 1.4e-56 190.4 1.4 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 EPE24994.1 - 4.8e-05 22.7 1.5 7.6e-05 22.1 0.2 1.9 2 0 0 2 2 2 1 Carbohydrate kinase eIF-5_eIF-2B PF01873.12 EPE24995.1 - 1.6e-39 134.3 0.0 2.6e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EPE24995.1 - 5.3e-23 80.7 0.4 5.3e-23 80.7 0.3 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon HEAT PF02985.17 EPE24996.1 - 1.2e-05 24.9 0.5 0.32 11.2 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EPE24996.1 - 0.02 15.3 3.0 5 7.7 0.0 4.3 3 0 0 3 3 3 0 HEAT-like repeat RelB PF04221.7 EPE24996.1 - 0.055 13.2 0.1 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 RelB antitoxin Arm PF00514.18 EPE24996.1 - 0.26 11.1 5.5 11 5.9 0.1 4.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DNA_pol_lambd_f PF10391.4 EPE24997.1 - 4.9e-18 64.4 0.6 4.9e-18 64.4 0.4 2.1 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 EPE24997.1 - 1.6e-16 60.3 0.0 5.3e-16 58.6 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EPE24997.1 - 4.7e-15 55.0 0.0 1.2e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 EPE24997.1 - 2e-09 37.5 0.2 6.3e-08 32.6 0.2 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EPE24997.1 - 0.00016 21.7 0.1 0.032 14.4 0.0 2.3 1 1 1 2 2 2 2 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EPE24997.1 - 0.02 15.2 0.3 0.25 11.6 0.0 2.7 3 0 0 3 3 3 0 Nucleotidyltransferase domain 5_3_exonuc PF01367.15 EPE24997.1 - 0.078 13.2 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold TFIIE_alpha PF02002.12 EPE24998.1 - 2.7e-13 49.3 0.0 4.7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit SURF2 PF05477.6 EPE24998.1 - 0.3 10.1 3.2 0.53 9.3 2.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NOA36 PF06524.7 EPE24998.1 - 2.5 7.2 11.5 2.3 7.3 4.1 2.1 2 0 0 2 2 2 0 NOA36 protein PseudoU_synth_1 PF01416.15 EPE24999.1 - 2.4e-21 76.1 0.0 9.4e-10 38.8 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase Sec31 PF11549.3 EPE24999.1 - 0.04 13.5 1.4 0.09 12.4 0.9 1.5 1 0 0 1 1 1 0 Protein transport protein SEC31 Mito_carr PF00153.22 EPE25000.1 - 1.2e-69 230.1 4.3 1.2e-22 79.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.15 EPE25001.1 - 3.5e-27 94.7 0.0 9.7e-14 51.3 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Med22 PF06179.7 EPE25002.1 - 4.9e-17 61.9 0.0 9.3e-17 61.0 0.0 1.4 2 0 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex UCH PF00443.24 EPE25003.1 - 2.6e-44 151.3 1.3 1.1e-43 149.2 0.9 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 EPE25003.1 - 1.7e-38 132.0 0.1 7e-38 130.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 EPE25003.1 - 4.9e-20 72.1 0.6 8.7e-20 71.3 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_P_pop3 PF08228.6 EPE25004.1 - 3.7e-13 49.5 0.1 3.3e-10 40.0 0.0 2.6 3 0 0 3 3 3 2 RNase P subunit Pop3 TFIIA PF03153.8 EPE25005.1 - 0.00057 19.9 9.7 0.00067 19.6 6.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ADH_N PF08240.7 EPE25006.1 - 5.6e-08 32.5 0.0 4.3e-06 26.4 0.0 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE25006.1 - 8.8e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MAPEG PF01124.13 EPE25007.1 - 2e-20 72.7 1.6 2.5e-20 72.3 1.1 1.1 1 0 0 1 1 1 1 MAPEG family HET PF06985.6 EPE25008.1 - 1e-29 103.4 1.8 2e-29 102.5 1.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PRCC PF10253.4 EPE25009.1 - 3.5e-38 132.1 3.5 3.5e-38 132.1 2.4 2.9 2 1 0 3 3 3 2 Mitotic checkpoint regulator, MAD2B-interacting SIN1 PF05422.7 EPE25010.1 - 8.3e-42 143.3 10.0 6.8e-24 84.2 0.0 3.3 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) RBD PF02196.10 EPE25010.1 - 0.0011 18.7 0.2 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 Raf-like Ras-binding domain TUG-UBL1 PF11470.3 EPE25010.1 - 0.0026 17.6 0.0 0.0083 16.0 0.0 1.8 1 0 0 1 1 1 1 GLUT4 regulating protein TUG GTP_cyclohydro2 PF00925.15 EPE25010.1 - 0.045 12.9 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 GTP cyclohydrolase II Glyco_transf_8 PF01501.15 EPE25012.1 - 5e-05 22.7 0.7 0.0011 18.4 0.5 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Antimicrobial20 PF08256.6 EPE25013.1 - 6.5 7.3 5.7 41 4.9 0.3 2.7 1 1 1 2 2 2 0 Aurein-like antibiotic peptide Anillin PF08174.6 EPE25016.1 - 5e-34 117.3 0.7 1.5e-33 115.8 0.5 1.9 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EPE25016.1 - 6.4e-08 32.7 0.0 3.2e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 PH domain SET PF00856.23 EPE25017.1 - 2.4e-11 44.2 0.0 3.4e-10 40.4 0.0 2.5 2 1 0 2 2 2 1 SET domain SAF PF08666.7 EPE25017.1 - 0.03 14.7 0.1 10 6.5 0.0 2.4 2 0 0 2 2 2 0 SAF domain PASTA PF03793.14 EPE25017.1 - 0.13 11.9 0.1 0.36 10.5 0.1 1.8 1 0 0 1 1 1 0 PASTA domain SKG6 PF08693.5 EPE25019.1 - 4.1e-05 22.8 0.2 8.9e-05 21.7 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SF3b1 PF08920.5 EPE25019.1 - 0.35 10.9 8.6 0.03 14.3 2.5 1.8 2 0 0 2 2 2 0 Splicing factor 3B subunit 1 SAGA-Tad1 PF12767.2 EPE25019.1 - 0.42 10.2 5.3 1.7 8.2 3.7 1.9 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit adh_short PF00106.20 EPE25020.1 - 9.6e-26 90.6 0.0 1.3e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE25020.1 - 8e-23 81.4 0.0 9.5e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE25020.1 - 2.5e-07 30.5 0.0 3.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPE25020.1 - 0.085 12.6 0.8 0.19 11.5 0.5 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F-box-like PF12937.2 EPE25022.1 - 0.071 12.8 0.2 0.27 10.9 0.2 2.1 1 0 0 1 1 1 0 F-box-like DUF4389 PF14333.1 EPE25025.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) zf-C2H2 PF00096.21 EPE25027.1 - 0.00037 20.6 5.2 0.0046 17.2 0.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE25027.1 - 0.0065 16.7 4.4 0.06 13.7 0.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger CTD PF12815.2 EPE25027.1 - 0.052 13.9 13.1 0.048 14.0 7.5 2.0 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 zf-H2C2_2 PF13465.1 EPE25027.1 - 9 6.7 8.9 1.4 9.3 0.7 2.6 3 0 0 3 3 3 0 Zinc-finger double domain PNGaseA PF12222.3 EPE25028.1 - 7.1e-112 374.3 5.6 1.1e-111 373.7 3.9 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Acetyltransf_2 PF00797.12 EPE25029.1 - 8e-31 107.4 0.1 5.7e-29 101.3 0.1 2.8 1 1 0 1 1 1 1 N-acetyltransferase zf-RING_6 PF14835.1 EPE25030.1 - 0.0009 18.9 6.8 0.0014 18.3 4.7 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EPE25030.1 - 0.0026 17.4 11.1 0.0039 16.8 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE25030.1 - 0.45 10.2 12.2 0.72 9.6 8.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPE25030.1 - 6 6.9 13.9 9.9 6.2 9.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2424 PF10340.4 EPE25031.1 - 3.8e-21 75.1 0.0 1e-13 50.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EPE25031.1 - 2.3e-19 69.8 0.0 4.4e-19 68.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE25031.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EPE25031.1 - 0.31 9.6 1.6 4.3 5.9 0.1 2.1 2 0 0 2 2 2 0 Carboxylesterase family U3_snoRNA_assoc PF08297.6 EPE25032.1 - 1e-08 35.2 0.7 4.9e-08 33.1 0.5 2.2 1 0 0 1 1 1 1 U3 snoRNA associated SAP PF02037.22 EPE25033.1 - 6.1e-11 41.5 0.6 6.1e-11 41.5 0.4 2.1 3 0 0 3 3 3 1 SAP domain TFIIB PF00382.14 EPE25033.1 - 0.07 12.9 0.0 9.4 6.1 0.0 2.8 2 0 0 2 2 2 0 Transcription factor TFIIB repeat DUF676 PF05057.9 EPE25034.1 - 4.7e-43 147.0 0.2 2.2e-26 92.5 0.0 3.2 2 1 1 3 3 3 3 Putative serine esterase (DUF676) PGAP1 PF07819.8 EPE25034.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein IBR PF01485.16 EPE25035.1 - 2.8e-11 43.0 45.0 3e-07 30.2 7.3 3.5 3 1 0 3 3 3 2 IBR domain RNase_H PF00075.19 EPE25036.1 - 2.4e-19 69.9 0.0 4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EPE25036.1 - 0.0036 17.0 0.0 0.17 11.6 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase-like Daxx PF03344.10 EPE25037.1 - 0.0026 16.3 12.3 0.0026 16.3 8.5 2.1 2 0 0 2 2 2 1 Daxx Family RXT2_N PF08595.6 EPE25037.1 - 0.075 12.8 11.1 0.14 11.9 0.5 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal BACK PF07707.10 EPE25037.1 - 0.15 11.9 0.0 0.46 10.3 0.0 1.7 2 0 0 2 2 2 0 BTB And C-terminal Kelch Nop14 PF04147.7 EPE25037.1 - 2 6.2 25.1 0.036 12.0 8.7 2.1 2 0 0 2 2 2 0 Nop14-like family DASH_Spc34 PF08657.5 EPE25038.1 - 1e-54 185.9 10.8 4.8e-53 180.4 7.5 2.0 1 1 0 1 1 1 1 DASH complex subunit Spc34 IncA PF04156.9 EPE25038.1 - 1.7e-06 27.7 5.1 2.2e-06 27.4 3.5 1.2 1 0 0 1 1 1 1 IncA protein Nsp1_C PF05064.8 EPE25038.1 - 0.0022 17.6 2.9 0.88 9.2 0.9 2.3 1 1 1 2 2 2 2 Nsp1-like C-terminal region Laminin_II PF06009.7 EPE25038.1 - 0.0079 15.9 0.1 2.4 7.9 0.0 2.2 2 0 0 2 2 2 1 Laminin Domain II Snapin_Pallidin PF14712.1 EPE25038.1 - 0.015 15.5 1.3 0.9 9.8 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin AAA_13 PF13166.1 EPE25038.1 - 0.025 13.0 0.6 0.03 12.7 0.4 1.1 1 0 0 1 1 1 0 AAA domain DUF1978 PF09321.5 EPE25038.1 - 0.038 13.4 10.9 0.055 12.9 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Uds1 PF15456.1 EPE25038.1 - 0.053 13.5 6.7 0.088 12.8 4.6 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Fib_alpha PF08702.5 EPE25038.1 - 0.11 12.6 0.6 0.19 11.8 0.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 EPE25038.1 - 0.11 11.4 5.5 0.16 11.0 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 EPE25038.1 - 0.19 11.6 13.6 0.55 10.0 8.1 2.1 1 1 0 2 2 2 0 Tropomyosin like Tropomyosin PF00261.15 EPE25038.1 - 0.25 10.4 14.6 0.61 9.1 10.2 1.6 1 1 0 1 1 1 0 Tropomyosin TBPIP PF07106.8 EPE25038.1 - 0.4 10.2 4.0 9.7 5.6 1.4 2.2 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 EPE25038.1 - 0.5 8.1 3.5 0.66 7.7 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.8 EPE25038.1 - 0.58 10.9 5.4 2.3 9.0 3.7 1.9 1 1 0 1 1 1 0 Occludin homology domain DUF4140 PF13600.1 EPE25038.1 - 0.94 9.9 9.3 6.1 7.3 4.0 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 EPE25038.1 - 1.2 9.0 6.3 31 4.4 5.0 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3552 PF12072.3 EPE25038.1 - 1.2 8.3 9.9 1.9 7.6 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Ax_dynein_light PF10211.4 EPE25038.1 - 1.4 8.6 9.9 10 5.9 0.1 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain SlyX PF04102.7 EPE25038.1 - 2.1 8.7 6.3 7.3 7.0 2.3 2.6 1 1 1 2 2 2 0 SlyX Lge1 PF11488.3 EPE25038.1 - 2.5 8.3 6.1 20 5.4 2.4 2.4 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DASH_Spc19 PF08287.6 EPE25038.1 - 3.2 7.3 8.4 6.1 6.4 5.6 1.6 1 1 0 1 1 1 0 Spc19 PspB PF06667.7 EPE25038.1 - 3.2 7.7 5.6 4.6 7.2 2.3 2.1 2 0 0 2 2 2 0 Phage shock protein B XhlA PF10779.4 EPE25038.1 - 3.9 7.4 7.3 2.5 8.0 2.0 2.5 2 1 1 3 3 3 0 Haemolysin XhlA DUF3429 PF11911.3 EPE25041.1 - 1.3e-38 132.1 11.2 1.7e-38 131.8 7.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Nucleoplasmin PF03066.10 EPE25041.1 - 0.055 12.9 7.3 0.097 12.1 5.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 EPE25041.1 - 0.36 11.0 9.8 0.8 9.8 6.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RNA_pol_3_Rpc31 PF11705.3 EPE25041.1 - 1.6 8.5 18.9 2.7 7.8 13.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 EPE25041.1 - 3.3 5.6 9.5 4.2 5.2 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 EPE25041.1 - 3.3 6.6 6.6 5 6.0 4.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CytochromB561_N PF09786.4 EPE25042.1 - 0.39 9.1 4.4 0.45 8.8 3.0 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF3984 PF13136.1 EPE25042.1 - 5.1 6.2 12.2 6.8 5.8 8.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) Pkinase PF00069.20 EPE25044.1 - 4.4e-21 75.2 0.1 8.4e-15 54.6 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25044.1 - 1.8e-13 50.1 0.0 2e-11 43.4 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase His_Phos_1 PF00300.17 EPE25045.1 - 1.5e-31 109.5 0.2 5.3e-31 107.8 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EPE25045.1 - 0.002 17.5 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1168 PF06658.7 EPE25046.1 - 7e-38 129.3 16.2 7e-38 129.3 11.2 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1168) Peptidase_U57 PF05582.7 EPE25046.1 - 0.025 13.5 1.0 0.037 12.9 0.7 1.3 1 0 0 1 1 1 0 YabG peptidase U57 MIP-T3 PF10243.4 EPE25046.1 - 0.69 8.3 14.0 0.92 7.9 9.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Peptidase_S49_N PF08496.5 EPE25046.1 - 2 8.1 4.7 3.3 7.5 3.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal U79_P34 PF03064.11 EPE25046.1 - 7.9 5.9 14.0 13 5.2 9.7 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Cpn60_TCP1 PF00118.19 EPE25047.1 - 2.6e-160 534.2 0.4 2.9e-160 534.0 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family adh_short PF00106.20 EPE25048.1 - 1.1e-28 100.1 2.1 2.3e-28 99.1 1.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE25048.1 - 8e-13 48.7 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE25048.1 - 2.6e-09 36.9 4.0 2.6e-08 33.7 2.8 2.1 1 1 0 1 1 1 1 KR domain DUF3115 PF11312.3 EPE25048.1 - 0.016 14.1 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) NAD_binding_10 PF13460.1 EPE25048.1 - 0.04 13.9 0.4 0.79 9.6 0.2 2.1 2 0 0 2 2 2 0 NADH(P)-binding DFP PF04127.10 EPE25048.1 - 0.048 13.2 0.2 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 EPE25048.1 - 0.099 12.0 0.2 0.86 8.9 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RF-1 PF00472.15 EPE25049.1 - 3.9e-14 52.4 1.9 6.1e-14 51.7 1.4 1.3 1 0 0 1 1 1 1 RF-1 domain Bromodomain PF00439.20 EPE25050.1 - 2.4e-18 65.8 0.6 7.5e-18 64.2 0.1 2.1 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 EPE25050.1 - 2.5e-08 33.5 0.0 1.4e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Bromodomain associated VanZ PF04892.7 EPE25051.1 - 4.3e-11 42.8 0.9 5.9e-11 42.4 0.6 1.1 1 0 0 1 1 1 1 VanZ like family YhhN PF07947.9 EPE25051.1 - 0.33 10.2 2.4 0.84 8.9 1.7 1.6 1 1 0 1 1 1 0 YhhN-like protein Nop PF01798.13 EPE25052.1 - 3.5e-60 201.6 0.1 6.3e-60 200.8 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EPE25052.1 - 6.3e-25 86.7 0.0 1.3e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EPE25052.1 - 1.8e-21 76.0 0.0 1.8e-21 76.0 0.0 2.7 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EPE25052.1 - 0.0099 15.5 22.7 0.019 14.6 15.7 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 EPE25052.1 - 0.5 10.2 11.2 0.84 9.5 7.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 EPE25052.1 - 2.1 7.4 14.2 3.8 6.6 9.9 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) AAA PF00004.24 EPE25053.1 - 1.4e-42 145.0 0.0 2.2e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EPE25053.1 - 5.2e-27 93.5 0.0 2.2e-26 91.4 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EPE25053.1 - 2.2e-19 69.0 6.3 2.2e-19 69.0 4.3 2.4 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EPE25053.1 - 2e-06 28.5 0.6 1.7e-05 25.6 0.0 2.6 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPE25053.1 - 6.8e-06 25.8 0.0 4.8e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPE25053.1 - 9.3e-06 25.6 0.2 0.0029 17.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EPE25053.1 - 1.1e-05 24.6 0.0 1.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EPE25053.1 - 1.4e-05 25.1 0.1 0.0016 18.5 0.1 2.8 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EPE25053.1 - 1.7e-05 24.2 0.0 4.6e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 EPE25053.1 - 3.4e-05 23.7 0.0 6.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPE25053.1 - 6.5e-05 23.0 0.0 0.0081 16.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 EPE25053.1 - 8.8e-05 22.5 0.0 0.0012 18.8 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EPE25053.1 - 0.00016 20.5 0.0 0.00028 19.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EPE25053.1 - 0.00019 20.4 0.0 0.0007 18.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EPE25053.1 - 0.00025 20.5 0.1 0.2 11.0 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.1 EPE25053.1 - 0.00053 19.8 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPE25053.1 - 0.0037 16.3 0.1 0.16 11.0 0.0 2.6 2 1 1 3 3 3 1 Zeta toxin AAA_18 PF13238.1 EPE25053.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EPE25053.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPE25053.1 - 0.018 14.7 0.0 0.065 12.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EPE25053.1 - 0.019 14.1 0.0 0.06 12.5 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EPE25053.1 - 0.027 14.1 0.2 0.23 11.1 0.0 2.3 2 1 1 3 3 3 0 Archaeal ATPase Torsin PF06309.6 EPE25053.1 - 0.031 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Torsin PhoH PF02562.11 EPE25053.1 - 0.039 13.1 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EPE25053.1 - 0.045 13.4 0.0 0.59 9.7 0.0 2.1 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.10 EPE25053.1 - 0.046 13.5 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EPE25053.1 - 0.05 12.4 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_21 PF13304.1 EPE25053.1 - 0.056 13.3 0.3 3 7.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain Peptidase_M28 PF04389.12 EPE25053.1 - 0.081 12.6 0.1 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M28 AAA_28 PF13521.1 EPE25053.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain USP8_dimer PF08969.6 EPE25053.1 - 0.16 11.9 3.9 0.31 11.0 2.1 1.9 2 0 0 2 2 2 0 USP8 dimerisation domain Prefoldin_2 PF01920.15 EPE25054.1 - 6.2e-18 64.5 6.5 6.2e-18 64.5 4.5 2.0 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 EPE25054.1 - 3.7e-07 29.8 5.3 1.1e-06 28.3 3.7 1.8 1 1 0 1 1 1 1 Prefoldin subunit DUF1515 PF07439.6 EPE25054.1 - 0.0016 18.2 2.5 0.025 14.3 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1515) MIP-T3 PF10243.4 EPE25054.1 - 0.0065 15.0 1.6 0.0065 15.0 1.1 2.0 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Scaffolding_pro PF11418.3 EPE25054.1 - 0.45 10.8 3.6 1.2 9.5 0.1 2.2 1 1 1 2 2 2 0 Phi29 scaffolding protein APG6 PF04111.7 EPE25054.1 - 2.4 7.1 10.8 0.57 9.1 3.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DivIC PF04977.10 EPE25054.1 - 3.1 7.3 16.3 1.9 8.0 1.0 3.2 3 0 0 3 3 3 0 Septum formation initiator IncA PF04156.9 EPE25054.1 - 5.6 6.5 12.9 0.77 9.3 4.5 1.9 1 1 1 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 EPE25054.1 - 6.7 6.4 16.3 11 5.7 1.0 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Acetyltransf_1 PF00583.19 EPE25055.1 - 6e-13 48.6 0.0 8.2e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE25055.1 - 4.4e-07 29.9 0.0 6.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE25055.1 - 4.5e-06 26.7 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE25055.1 - 0.00021 20.9 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EPE25055.1 - 0.0073 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE25055.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EPE25055.1 - 0.016 15.4 0.0 0.019 15.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPE25055.1 - 0.052 13.4 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EPE25056.1 - 1.6e-58 197.9 0.0 1.9e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25056.1 - 3.1e-32 111.6 0.0 3.9e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE25056.1 - 4.6e-05 22.5 0.0 0.00013 21.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPE25056.1 - 0.0035 16.4 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE25056.1 - 0.022 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPE25056.1 - 0.084 11.6 0.1 0.28 9.9 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase SAC3_GANP PF03399.11 EPE25058.1 - 1.6e-09 37.5 0.1 2.7e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPE25058.1 - 1.5e-06 28.0 0.0 2.6e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 HlyIII PF03006.15 EPE25059.1 - 4.3e-59 199.5 15.8 5.1e-59 199.3 11.0 1.0 1 0 0 1 1 1 1 Haemolysin-III related TMEM238 PF15125.1 EPE25059.1 - 0.049 13.5 0.3 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 TMEM238 protein family Ni_hydr_CYTB PF01292.15 EPE25059.1 - 0.13 11.6 10.0 0.035 13.5 3.1 2.2 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF4405 PF14358.1 EPE25059.1 - 0.45 10.6 9.6 0.55 10.3 0.4 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4405) Annexin PF00191.15 EPE25061.1 - 4.7e-66 218.6 9.6 8.1e-19 67.3 0.1 4.2 4 0 0 4 4 4 4 Annexin MiaE PF06175.6 EPE25061.1 - 0.016 14.6 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) Spore_YpjB PF09577.5 EPE25061.1 - 0.023 14.2 1.1 0.12 11.9 0.1 2.2 1 1 1 2 2 2 0 Sporulation protein YpjB (SpoYpjB) Acetyltransf_11 PF13720.1 EPE25061.1 - 0.048 13.8 2.9 16 5.7 0.0 4.0 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PAT1 PF09770.4 EPE25061.1 - 3.6 5.7 24.2 5.2 5.1 16.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2_4 PF13894.1 EPE25062.1 - 0.06 13.7 4.2 3.9 8.0 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE25062.1 - 0.07 13.4 6.7 1.1 9.7 0.9 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.2 EPE25062.1 - 0.1 12.8 0.6 0.27 11.4 0.4 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type APH PF01636.18 EPE25063.1 - 6.2e-10 39.2 0.0 2e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Dus PF01207.12 EPE25064.1 - 3.4e-47 160.8 0.0 4.1e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Atg14 PF10186.4 EPE25065.1 - 7.9e-06 25.0 0.0 1.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 GAS PF13851.1 EPE25065.1 - 0.032 13.4 7.3 0.05 12.7 5.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EPE25065.1 - 0.54 9.8 5.1 0.85 9.1 3.5 1.3 1 0 0 1 1 1 0 IncA protein Hydrolase_6 PF13344.1 EPE25066.1 - 1e-20 73.4 0.0 2.5e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE25066.1 - 6.3e-18 64.2 0.0 1.9e-17 62.6 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EPE25066.1 - 0.0013 18.9 0.0 0.22 11.7 0.0 2.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPE25066.1 - 0.0067 16.8 0.0 0.37 11.1 0.0 2.9 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase ERF PF04404.7 EPE25066.1 - 0.1 12.1 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 ERF superfamily Aldo_ket_red PF00248.16 EPE25067.1 - 2.2e-56 190.7 0.0 2.6e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cyclin_N PF00134.18 EPE25070.1 - 1.1e-13 50.9 0.4 3e-13 49.4 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPE25070.1 - 0.00031 20.6 0.0 0.047 13.6 0.0 2.6 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 EPE25070.1 - 0.0076 16.0 0.7 0.026 14.3 0.1 2.1 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Abhydrolase_3 PF07859.8 EPE25071.1 - 4.5e-42 144.0 0.0 5.6e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EPE25071.1 - 6.6e-07 28.4 0.2 1.3e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EPE25071.1 - 2.5e-05 24.2 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE25071.1 - 0.00011 21.9 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE25071.1 - 0.0061 15.8 0.4 2.6 7.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EPE25071.1 - 0.013 15.0 0.1 0.037 13.4 0.1 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase F-box-like PF12937.2 EPE25072.1 - 2e-05 24.2 0.4 7.5e-05 22.3 0.3 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EPE25072.1 - 0.015 15.3 0.1 2.5 8.4 0.0 3.8 2 0 0 2 2 2 0 Leucine Rich repeat LRR_8 PF13855.1 EPE25072.1 - 0.038 13.7 11.9 0.54 10.0 1.4 3.7 2 1 0 3 3 3 0 Leucine rich repeat DUF1515 PF07439.6 EPE25073.1 - 0.04 13.7 2.2 0.051 13.3 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF1765 PF08578.5 EPE25075.1 - 2.8e-46 156.6 10.0 3.1e-45 153.3 7.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) TFR_dimer PF04253.10 EPE25076.1 - 2e-27 95.2 0.0 3.8e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EPE25076.1 - 4.4e-19 68.9 0.0 1.1e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EPE25076.1 - 3.4e-06 26.6 0.0 6.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 EPE25076.1 - 0.24 10.6 0.0 0.44 9.7 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Vps35 PF03635.12 EPE25077.1 - 1.6e-292 972.3 12.3 2.1e-290 965.3 8.5 2.0 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribonuc_L-PSP PF01042.16 EPE25077.1 - 0.055 13.2 0.2 1.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Endoribonuclease L-PSP FAD_binding_4 PF01565.18 EPE25079.1 - 8.2e-21 73.9 0.4 1.6e-20 72.9 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE25079.1 - 0.0027 17.5 0.1 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like DLH PF01738.13 EPE25079.1 - 0.13 11.5 0.1 0.24 10.6 0.1 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Glyco_transf_49 PF13896.1 EPE25080.1 - 0.066 12.3 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan GTP_EFTU PF00009.22 EPE25082.1 - 6e-54 182.3 0.0 8.8e-54 181.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EPE25082.1 - 7.2e-25 86.6 0.0 1.5e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EPE25082.1 - 3.5e-16 58.8 0.0 3.3e-15 55.7 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPE25082.1 - 3.3e-06 27.1 0.0 7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EPE25082.1 - 0.0036 16.8 0.0 0.15 11.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EPE25082.1 - 0.03 14.2 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Vps5 PF09325.5 EPE25083.1 - 1.9e-12 46.9 0.4 3.7e-12 46.0 0.3 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EPE25083.1 - 1.7e-10 40.6 0.0 3.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 PX domain CCT_2 PF09425.5 EPE25083.1 - 0.19 11.2 3.7 6.1 6.4 0.0 2.6 2 0 0 2 2 2 0 Divergent CCT motif ADH_N PF08240.7 EPE25084.1 - 2e-26 91.9 2.4 4.1e-26 90.8 1.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE25084.1 - 1.3e-18 66.7 0.1 5.1e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase TrkA_N PF02254.13 EPE25084.1 - 0.0038 17.2 0.0 0.007 16.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 EPE25084.1 - 0.0059 16.7 0.1 0.028 14.5 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EPE25084.1 - 0.012 15.3 0.1 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EPE25084.1 - 0.029 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_18 PF12847.2 EPE25084.1 - 0.032 14.8 0.0 0.069 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain ThiF PF00899.16 EPE25084.1 - 0.04 13.7 0.6 0.084 12.6 0.4 1.5 1 0 0 1 1 1 0 ThiF family Pyr_redox_2 PF07992.9 EPE25084.1 - 0.053 13.4 0.1 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EPE25084.1 - 0.053 12.8 0.3 0.13 11.5 0.1 1.6 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Semialdhyde_dh PF01118.19 EPE25084.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPE25084.1 - 0.077 12.1 0.1 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EPE25084.1 - 0.082 12.9 0.3 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EPE25084.1 - 0.087 12.3 0.3 0.18 11.3 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EPE25084.1 - 0.14 12.6 0.7 0.48 10.8 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NADH_4Fe-4S PF10589.4 EPE25084.1 - 0.3 10.2 4.9 0.61 9.2 3.4 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region JAB PF01398.16 EPE25085.1 - 4.6e-10 39.2 0.0 8.3e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EPE25085.1 - 1.8e-06 27.9 0.1 4.3e-05 23.5 0.1 2.6 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function ChlamPMP_M PF07548.6 EPE25085.1 - 0.049 13.3 0.1 0.088 12.5 0.0 1.4 1 1 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain DUF1087 PF06465.8 EPE25087.1 - 0.0074 16.1 0.7 0.014 15.3 0.5 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) ArfGap PF01412.13 EPE25088.1 - 5.2e-32 110.0 0.0 8.9e-32 109.3 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.17 EPE25089.1 - 1.2e-29 101.7 0.3 1.1e-12 47.3 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE25089.1 - 6e-23 80.6 0.0 4.7e-11 42.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE25089.1 - 3e-10 39.7 0.0 0.00032 20.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 EPE25089.1 - 0.029 14.0 0.2 11 5.8 0.0 2.7 3 0 0 3 3 3 0 DbpA RNA binding domain DLIC PF05783.6 EPE25089.1 - 0.072 11.7 0.4 3.1 6.3 0.1 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Limkain-b1 PF11608.3 EPE25089.1 - 0.09 12.5 0.1 17 5.2 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 API5 PF05918.6 EPE25089.1 - 1.1 7.6 6.3 2 6.8 4.3 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Flavodoxin_1 PF00258.20 EPE25090.1 - 3.1e-33 114.7 0.0 5.5e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EPE25090.1 - 3.1e-32 111.8 0.0 6.4e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPE25090.1 - 1.2e-16 61.2 0.0 3.7e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EPE25090.1 - 0.00051 20.0 0.0 0.00097 19.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.2 EPE25090.1 - 0.00067 19.1 0.0 0.0025 17.2 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin domain Cas_APE2256 PF09651.5 EPE25090.1 - 0.015 14.9 0.0 0.23 11.1 0.0 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_APE2256) p450 PF00067.17 EPE25091.1 - 1.3e-43 149.2 0.0 4.6e-31 107.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 3Beta_HSD PF01073.14 EPE25092.1 - 6.3e-45 153.0 0.0 8.2e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE25092.1 - 2e-29 102.6 0.0 2.7e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPE25092.1 - 6.6e-13 48.1 0.0 9.1e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPE25092.1 - 3.2e-11 43.5 0.0 6.1e-11 42.6 0.0 1.4 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPE25092.1 - 1.3e-10 40.6 0.0 4.5e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EPE25092.1 - 0.0001 22.2 0.2 0.00035 20.5 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPE25092.1 - 0.0002 20.3 0.0 0.0025 16.7 0.0 2.5 2 2 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EPE25092.1 - 0.0042 16.7 0.0 0.052 13.2 0.0 2.3 1 1 0 1 1 1 1 KR domain DAO PF01266.19 EPE25093.1 - 1.6e-41 142.4 0.0 2e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE25093.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE25093.1 - 0.0016 18.3 0.0 0.025 14.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Bystin PF05291.6 EPE25094.1 - 1.7e-126 421.2 0.0 2.3e-126 420.8 0.0 1.1 1 0 0 1 1 1 1 Bystin GFO_IDH_MocA PF01408.17 EPE25096.1 - 1.8e-14 54.2 0.0 3.5e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPE25096.1 - 0.00021 21.0 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Mito_fiss_Elm1 PF06258.6 EPE25096.1 - 0.13 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 DHquinase_I PF01487.10 EPE25098.1 - 4.5e-41 140.9 0.0 9.9e-41 139.8 0.0 1.5 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.17 EPE25098.1 - 7.1e-18 64.9 0.0 1.4e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 EPE25098.1 - 6.2e-14 51.8 0.0 1.6e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EPE25098.1 - 1.4e-13 51.1 0.1 1.5e-12 47.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EPE25098.1 - 0.062 13.7 0.1 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AAA_17 PF13207.1 EPE25098.1 - 0.13 13.1 0.0 0.85 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain ThiF PF00899.16 EPE25098.1 - 0.16 11.8 0.4 0.48 10.2 0.1 1.9 2 0 0 2 2 2 0 ThiF family Fungal_trans PF04082.13 EPE25099.1 - 4.7e-26 91.2 0.1 8.1e-26 90.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE25099.1 - 6.6e-08 32.3 13.5 1e-07 31.7 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF500 PF04366.7 EPE25101.1 - 3.9e-43 145.9 0.1 6.5e-43 145.1 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) NAD_binding_6 PF08030.7 EPE25103.1 - 1.2e-18 67.4 0.0 2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPE25103.1 - 9.4e-14 51.5 8.5 9.4e-14 51.5 5.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EPE25103.1 - 3.7e-12 46.0 0.0 7.9e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EPE25103.1 - 0.0038 17.7 0.0 0.12 12.9 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Rho_Binding PF08912.6 EPE25105.1 - 0.036 14.3 0.6 0.036 14.3 0.4 2.9 3 1 0 3 3 3 0 Rho Binding DUF2259 PF10016.4 EPE25105.1 - 0.077 12.7 2.5 0.15 11.7 0.4 1.9 1 1 1 2 2 2 0 Predicted secreted protein (DUF2259) DUF1779 PF08680.5 EPE25105.1 - 0.23 11.2 7.6 0.024 14.4 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1779) DUF4172 PF13776.1 EPE25105.1 - 0.97 9.5 4.7 1.1 9.3 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4172) COG2 PF06148.6 EPE25105.1 - 1.1 9.1 5.9 4.3 7.2 3.1 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.1 EPE25105.1 - 1.9 7.3 6.1 2.6 6.9 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.6 EPE25105.1 - 2.1 8.2 4.7 1.6 8.6 0.3 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 EPE25105.1 - 2.8 5.6 8.0 3.2 5.5 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 EPE25105.1 - 5.1 6.7 15.5 1.1 8.8 7.5 2.1 1 1 1 2 2 2 0 Mnd1 family APG6 PF04111.7 EPE25105.1 - 10 5.0 15.8 0.33 9.9 6.9 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Val_tRNA-synt_C PF10458.4 EPE25105.1 - 10 6.3 11.5 12 6.0 1.6 3.5 1 1 2 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DPBB_1 PF03330.13 EPE25106.1 - 3.8e-06 26.8 0.0 1.6e-05 24.8 0.0 2.1 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EPE25106.1 - 2.2e-05 24.1 0.7 6.2e-05 22.6 0.2 1.9 2 0 0 2 2 2 1 Barwin family Pollen_allerg_1 PF01357.16 EPE25106.1 - 0.014 15.1 1.3 0.024 14.4 0.9 1.3 1 0 0 1 1 1 0 Pollen allergen Cerato-platanin PF07249.7 EPE25106.1 - 0.027 14.4 2.4 0.05 13.6 0.4 2.3 1 1 1 2 2 2 0 Cerato-platanin BNR PF02012.15 EPE25106.1 - 0.098 12.5 0.2 0.37 10.7 0.1 2.1 1 0 0 1 1 1 0 BNR/Asp-box repeat Kelch_5 PF13854.1 EPE25108.1 - 0.0022 17.8 1.2 0.03 14.2 0.0 3.3 2 1 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 EPE25108.1 - 0.032 13.9 12.0 0.9 9.3 0.1 4.9 5 0 0 5 5 5 0 Galactose oxidase, central domain SKG6 PF08693.5 EPE25108.1 - 0.3 10.4 2.4 0.17 11.2 0.1 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain LRR_4 PF12799.2 EPE25109.1 - 2.6e-08 33.2 6.0 2.6e-07 30.0 3.7 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE25109.1 - 3e-07 30.1 2.4 3e-07 30.1 1.7 1.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EPE25109.1 - 0.00017 21.1 7.0 0.25 11.5 0.4 4.5 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EPE25109.1 - 0.024 14.7 6.6 0.63 10.4 0.2 4.1 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 EPE25109.1 - 0.51 10.5 5.7 1.3 9.2 0.4 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Methyltrn_RNA_3 PF02598.12 EPE25110.1 - 1.4e-76 257.5 0.0 1.7e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase FMO-like PF00743.14 EPE25111.1 - 3.3e-45 154.3 0.1 7e-28 97.1 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EPE25111.1 - 6.4e-15 55.7 0.0 2.9e-14 53.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE25111.1 - 1.3e-12 47.7 1.7 1.7e-10 40.9 0.0 3.8 4 2 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPE25111.1 - 1e-10 41.0 0.1 1.5e-09 37.2 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPE25111.1 - 1e-07 32.0 0.0 1e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE25111.1 - 3.2e-07 29.6 0.0 0.00091 18.3 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 EPE25111.1 - 5.4e-06 26.3 0.0 2.6e-05 24.1 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EPE25111.1 - 0.0077 14.7 0.2 0.28 9.5 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 EPE25111.1 - 0.15 12.4 0.4 7.6 7.0 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE25111.1 - 0.17 10.7 0.2 0.96 8.2 0.0 2.3 4 0 0 4 4 4 0 FAD dependent oxidoreductase IF4E PF01652.13 EPE25112.1 - 4.9e-52 175.7 0.2 6.8e-52 175.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Chromo PF00385.19 EPE25113.1 - 0.024 14.2 0.9 0.06 13.0 0.6 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Corona_S2 PF01601.11 EPE25113.1 - 0.055 11.5 4.8 0.089 10.8 3.3 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein IncA PF04156.9 EPE25113.1 - 0.72 9.4 37.7 2.1 7.8 10.9 2.9 1 1 1 2 2 2 0 IncA protein Ribosomal_L4 PF00573.17 EPE25114.1 - 4.8e-38 130.4 0.2 6.3e-38 130.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EPE25114.1 - 7.4e-27 93.0 0.2 2.2e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain ELO PF01151.13 EPE25116.1 - 6.9e-64 215.5 18.7 8.1e-64 215.3 13.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family HET PF06985.6 EPE25117.1 - 2.3e-26 92.6 0.0 4.8e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COX5A PF02284.11 EPE25118.1 - 1.9e-40 137.1 0.3 2.6e-40 136.7 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DHC_N1 PF08385.7 EPE25118.1 - 0.056 11.8 0.2 1.4 7.2 0.0 2.0 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 Peptidase_C48 PF02902.14 EPE25119.1 - 2.7e-33 115.4 0.0 1.4e-32 113.1 0.0 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF508 PF04370.7 EPE25120.1 - 0.022 14.3 0.4 0.061 12.9 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF508) ERM PF00769.14 EPE25120.1 - 3.9 6.9 47.9 1.4 8.4 8.6 3.5 1 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF972 PF06156.8 EPE25120.1 - 7.7 6.9 40.6 3.6 7.9 2.1 6.4 2 1 4 6 6 6 0 Protein of unknown function (DUF972) Cupin_1 PF00190.17 EPE25122.1 - 1.3e-21 76.5 0.1 1.7e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EPE25122.1 - 3.6e-21 74.4 1.2 1.3e-11 43.8 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EPE25122.1 - 5e-08 32.2 0.1 0.00038 19.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EPE25122.1 - 3.1e-05 23.6 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.14 EPE25122.1 - 5.3e-05 22.9 0.1 0.17 11.5 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain NAD_binding_8 PF13450.1 EPE25123.1 - 1.5e-12 47.3 0.1 5.2e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EPE25123.1 - 2.5e-07 30.1 0.0 1.9e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EPE25123.1 - 1.8e-05 23.8 0.5 2.5e-05 23.3 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EPE25123.1 - 3e-05 24.1 0.0 0.017 15.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPE25123.1 - 9.5e-05 21.6 0.5 0.00028 20.0 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPE25123.1 - 0.00046 18.7 0.5 0.00089 17.8 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EPE25123.1 - 0.00056 18.9 3.3 0.001 18.0 0.8 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPE25123.1 - 0.0015 18.4 0.2 0.0034 17.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EPE25123.1 - 0.007 15.0 0.1 0.011 14.4 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.12 EPE25123.1 - 0.0085 15.2 0.1 0.014 14.4 0.1 1.2 1 0 0 1 1 1 1 Thi4 family GMC_oxred_N PF00732.14 EPE25123.1 - 0.0087 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox PF00070.22 EPE25123.1 - 0.014 15.7 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE25123.1 - 0.029 14.1 0.2 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EPE25123.1 - 0.073 11.9 0.1 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EPE25123.1 - 0.12 11.4 0.2 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EPE25123.1 - 0.19 11.7 0.2 0.37 10.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Staygreen PF12638.2 EPE25124.1 - 0.015 14.8 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Staygreen protein Homeobox PF00046.24 EPE25126.1 - 5e-09 35.6 1.2 2e-08 33.7 0.8 2.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EPE25126.1 - 0.0021 17.7 0.0 0.0098 15.5 0.0 2.2 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EPE25126.1 - 0.029 13.4 0.4 0.067 12.2 0.3 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Glycogen_syn PF05693.8 EPE25127.1 - 0 1136.8 0.0 0 1136.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EPE25127.1 - 2.1e-06 27.2 0.0 0.0058 16.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EPE25127.1 - 6.3e-06 26.4 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_hydro_3 PF00933.16 EPE25129.1 - 9.9e-75 251.2 0.0 9.3e-40 136.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE25129.1 - 1.8e-43 148.6 0.0 1.3e-42 145.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE25129.1 - 1.6e-22 79.2 0.3 3e-22 78.3 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Herpes_U5 PF05999.6 EPE25130.1 - 0.045 12.3 0.4 0.068 11.7 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus U5-like family AAA-ATPase_like PF09820.4 EPE25130.1 - 0.095 11.8 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase Apolipoprotein PF01442.13 EPE25131.1 - 0.032 13.7 113.6 0.078 12.4 1.5 14.0 4 3 5 10 10 10 0 Apolipoprotein A1/A4/E domain Cyclin PF08613.6 EPE25136.1 - 3e-11 43.9 0.0 4.2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin CRC_subunit PF08624.5 EPE25137.1 - 2.8e-59 199.0 0.1 4e-59 198.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Pkinase PF00069.20 EPE25138.1 - 1.1e-69 234.4 0.0 1.7e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25138.1 - 1.6e-30 106.0 0.0 2.2e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EPE25138.1 - 1.2e-14 54.5 0.2 6.6e-14 52.1 0.1 2.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPE25138.1 - 5.3e-09 35.4 0.0 9.6e-09 34.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 EPE25138.1 - 0.00012 21.8 0.0 0.0004 20.1 0.0 2.0 1 1 0 1 1 1 1 C2 domain APH PF01636.18 EPE25138.1 - 0.0096 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.2 EPE25142.1 - 9e-22 77.2 0.0 1.3e-09 38.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPE25142.1 - 3.9e-19 68.2 0.0 6.8e-08 32.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EPE25142.1 - 1.9e-17 62.1 0.2 1e-08 34.5 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EPE25142.1 - 2.7e-15 56.4 0.1 1.3e-06 28.7 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE25142.1 - 2e-12 46.0 0.3 2.5e-05 24.0 0.0 4.9 3 1 0 3 3 3 3 Ankyrin repeat NACHT PF05729.7 EPE25142.1 - 3e-07 30.2 0.1 3.3e-06 26.8 0.0 2.7 3 0 0 3 3 3 1 NACHT domain NB-ARC PF00931.17 EPE25142.1 - 0.00025 20.0 0.0 0.00057 18.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EPE25142.1 - 0.0027 17.8 0.0 0.014 15.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPE25142.1 - 0.019 14.3 0.0 0.064 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Inhibitor_I78 PF11720.3 EPE25143.1 - 4.1e-13 48.8 0.0 6e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EPE25143.1 - 4.3e-05 23.5 0.0 5.8e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 Potato inhibitor I family FTP PF07504.8 EPE25143.1 - 0.02 14.3 0.2 0.032 13.7 0.1 1.4 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif DUF2668 PF10873.3 EPE25144.1 - 1.5 8.9 8.0 0.55 10.3 3.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2668) DUF3609 PF12259.3 EPE25144.1 - 2.5 6.6 4.4 0.54 8.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3609) SNARE PF05739.14 EPE25145.1 - 6e-18 64.2 2.7 2e-17 62.6 0.5 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EPE25145.1 - 1.9e-16 60.0 0.7 1.9e-16 60.0 0.5 3.3 3 1 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 EPE25145.1 - 0.0082 15.7 0.3 0.0082 15.7 0.2 2.8 3 1 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.4 EPE25145.1 - 0.035 14.2 0.8 1.7 8.8 0.0 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sed5p PF11416.3 EPE25145.1 - 0.055 12.9 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 EPE25145.1 - 0.055 13.2 1.0 0.7 9.7 0.0 2.8 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.7 EPE25145.1 - 0.23 11.7 7.8 4.7 7.5 0.1 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 EPE25145.1 - 4.8 5.7 9.1 0.12 11.0 0.5 2.2 3 0 0 3 3 3 0 Spc7 kinetochore protein SF-assemblin PF06705.6 EPE25145.1 - 4.9 6.2 10.4 0.82 8.7 1.0 2.7 3 0 0 3 3 3 0 SF-assemblin/beta giardin HET PF06985.6 EPE25147.1 - 2.9e-32 111.7 0.3 6.7e-32 110.5 0.2 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PRK PF00485.13 EPE25148.1 - 5.3e-05 22.8 0.0 7.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EPE25148.1 - 0.00071 20.3 0.4 0.011 16.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EPE25148.1 - 0.0055 16.2 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EPE25148.1 - 0.017 14.0 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 EPE25148.1 - 0.027 14.7 0.0 0.61 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EPE25148.1 - 0.065 12.3 0.1 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin CoaE PF01121.15 EPE25148.1 - 0.092 12.1 0.1 8.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_33 PF13671.1 EPE25148.1 - 0.093 12.6 0.1 2 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF1219 PF06755.7 EPE25148.1 - 0.095 12.2 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1219) Sugar_tr PF00083.19 EPE25149.1 - 5.2e-42 143.9 15.1 6.4e-42 143.6 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE25149.1 - 4.3e-09 35.5 10.7 5.9e-09 35.1 7.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily YrhC PF14143.1 EPE25149.1 - 0.095 12.6 0.4 0.89 9.5 0.1 2.5 1 1 1 2 2 2 0 YrhC-like protein Fungal_trans PF04082.13 EPE25150.1 - 9.2e-35 119.7 0.1 1.9e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribonuc_L-PSP PF01042.16 EPE25151.1 - 2.3e-23 82.2 0.0 2.7e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peripla_BP_6 PF13458.1 EPE25151.1 - 0.011 15.0 0.1 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Nitr_red_alph_N PF14710.1 EPE25151.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Respiratory nitrate reductase alpha N-terminal HET PF06985.6 EPE25152.1 - 6.1e-25 88.0 1.7 2.9e-24 85.7 1.2 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ndc1_Nup PF09531.5 EPE25153.1 - 0.22 9.8 5.2 0.3 9.4 3.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Asp PF00026.18 EPE25154.1 - 1.8e-60 204.8 1.3 2.8e-60 204.2 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPE25154.1 - 5.6e-08 32.8 0.0 8.2e-07 29.1 0.0 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EPE25154.1 - 0.088 12.3 0.1 0.37 10.3 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Abhydrolase_2 PF02230.11 EPE25155.1 - 3.2e-39 134.6 0.0 6e-38 130.4 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EPE25155.1 - 5.1e-11 42.5 0.0 8.7e-11 41.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE25155.1 - 3.4e-06 27.1 0.0 1e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPE25155.1 - 3.3e-05 23.4 0.0 4.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EPE25155.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold HHH_7 PF14635.1 EPE25155.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif UPF0565 PF10561.4 EPE25155.1 - 0.15 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Connexin_CCC PF10582.4 EPE25156.1 - 0.27 11.0 2.4 0.84 9.4 1.7 1.8 1 0 0 1 1 1 0 Gap junction channel protein cysteine-rich domain DUF3433 PF11915.3 EPE25157.1 - 1.2e-23 83.0 1.0 1.2e-23 83.0 0.7 4.1 5 0 0 5 5 5 3 Protein of unknown function (DUF3433) Acetyltransf_7 PF13508.1 EPE25158.1 - 2.1e-08 34.2 0.0 4.8e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE25158.1 - 6.4e-08 32.5 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE25158.1 - 0.0019 18.3 0.0 0.0077 16.3 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE25158.1 - 0.0071 16.1 0.2 0.23 11.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Pentapeptide_4 PF13599.1 EPE25158.1 - 0.011 15.5 1.8 0.018 14.7 1.2 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EPE25158.1 - 0.013 15.3 1.8 0.024 14.5 1.2 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) FR47 PF08445.5 EPE25158.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF3328 PF11807.3 EPE25159.1 - 1.5e-25 90.1 0.2 1.9e-25 89.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AA_permease_2 PF13520.1 EPE25162.1 - 7.3e-44 149.9 60.1 1e-43 149.4 41.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE25162.1 - 4e-20 71.6 52.5 2.3e-19 69.1 36.4 1.9 1 1 0 1 1 1 1 Amino acid permease cEGF PF12662.2 EPE25163.1 - 0.019 14.6 0.4 0.052 13.1 0.3 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_3 PF12947.2 EPE25163.1 - 0.024 14.6 3.8 0.06 13.3 2.7 1.8 1 0 0 1 1 1 0 EGF domain EGF_CA PF07645.10 EPE25163.1 - 0.07 13.1 2.5 0.24 11.4 1.7 1.9 1 0 0 1 1 1 0 Calcium-binding EGF domain SCO1-SenC PF02630.9 EPE25164.1 - 8.2e-57 191.6 0.0 1.3e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EPE25164.1 - 0.0015 18.2 0.0 0.0044 16.6 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family GRAM PF02893.15 EPE25164.1 - 0.056 12.9 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 GRAM domain Thioredoxin_8 PF13905.1 EPE25164.1 - 0.06 13.4 0.0 0.16 12.1 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like Glyco_hydro_92 PF07971.7 EPE25166.1 - 4.9e-153 510.4 0.6 6e-153 510.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_transf_25 PF01755.12 EPE25167.1 - 3.3e-10 39.9 0.0 5.5e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF3679 PF12438.3 EPE25167.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3679) Esterase_phd PF10503.4 EPE25168.1 - 3.5e-21 75.4 0.3 5.5e-21 74.8 0.2 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EPE25168.1 - 4.4e-15 55.4 1.7 6.2e-15 54.9 1.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE25168.1 - 3.8e-06 26.7 0.1 5.9e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE25168.1 - 1.3e-05 25.2 0.1 3.3e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EPE25168.1 - 0.0011 18.4 0.2 0.002 17.6 0.1 1.3 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.23 EPE25168.1 - 0.0046 15.7 0.2 0.013 14.2 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Zn_clus PF00172.13 EPE25169.1 - 6.7e-05 22.7 7.6 0.00017 21.4 5.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 EPE25170.1 - 1.3e-17 64.2 0.0 9.4e-10 38.8 0.0 2.6 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) Glyco_hydro_18 PF00704.23 EPE25170.1 - 2.3e-09 37.1 0.0 4.8e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AAA_17 PF13207.1 EPE25170.1 - 0.00046 20.9 0.2 0.0016 19.2 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EPE25170.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EPE25170.1 - 0.012 15.8 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EPE25170.1 - 0.016 15.1 0.3 0.041 13.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPE25170.1 - 0.03 14.0 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EPE25170.1 - 0.035 13.5 0.0 0.089 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPE25170.1 - 0.039 13.9 0.1 0.097 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 EPE25170.1 - 0.058 12.8 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 EPE25170.1 - 0.064 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF815 PF05673.8 EPE25170.1 - 0.076 11.9 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EPE25170.1 - 0.11 12.4 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 EPE25170.1 - 0.12 11.8 0.5 0.3 10.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 EPE25170.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus MIP PF00230.15 EPE25174.1 - 6.1e-44 150.1 11.3 8.4e-44 149.7 7.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Rad60-SLD PF11976.3 EPE25175.1 - 3.6e-19 68.2 0.1 4.5e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EPE25175.1 - 3.5e-06 26.2 0.0 4.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Nckap1 PF09735.4 EPE25175.1 - 0.02 12.4 0.1 0.021 12.3 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein DUF111 PF01969.12 EPE25175.1 - 0.04 12.7 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF111 Pab87_oct PF13969.1 EPE25175.1 - 0.083 12.9 0.0 0.096 12.7 0.0 1.2 1 0 0 1 1 1 0 Pab87 octamerisation domain HET PF06985.6 EPE25177.1 - 1.3e-22 80.4 7.7 6.1e-22 78.2 5.3 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.18 EPE25178.1 - 3.3e-26 91.4 2.3 5.3e-26 90.7 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE25178.1 - 1.4e-11 44.1 0.0 4e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like NACHT PF05729.7 EPE25179.1 - 4.9e-09 36.0 0.1 2e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EPE25179.1 - 0.0068 16.5 0.0 0.032 14.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPE25179.1 - 0.046 14.0 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DUF1913 PF08931.5 EPE25180.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1913) AA_permease PF00324.16 EPE25181.1 - 1.8e-133 445.4 45.1 2.1e-133 445.1 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE25181.1 - 2e-31 108.9 48.4 2.6e-31 108.5 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease CD20 PF04103.10 EPE25181.1 - 0.007 16.3 3.5 0.007 16.3 2.4 3.6 3 1 0 3 3 3 1 CD20-like family Pectate_lyase_3 PF12708.2 EPE25182.1 - 1.2e-82 277.4 20.2 1.6e-63 214.8 6.9 3.0 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EPE25182.1 - 7e-08 31.8 0.8 0.0018 17.6 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase CrtC PF07143.6 EPE25183.1 - 1.1e-06 28.2 1.7 1.9e-06 27.4 1.2 1.4 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Ras PF00071.17 EPE25184.1 - 1.5e-55 186.9 0.0 1.8e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE25184.1 - 5.6e-16 59.1 0.0 8e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE25184.1 - 6.1e-10 38.6 0.0 9e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPE25184.1 - 0.00059 19.0 0.0 0.00069 18.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EPE25184.1 - 0.0013 18.0 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EPE25184.1 - 0.0037 16.0 0.0 0.0049 15.6 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EPE25184.1 - 0.017 15.0 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EPE25184.1 - 0.032 14.5 0.0 0.056 13.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EPE25184.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 EPE25184.1 - 0.14 11.6 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IU_nuc_hydro PF01156.14 EPE25185.1 - 6.4e-09 35.4 0.0 9.8e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PepX_N PF09168.5 EPE25185.1 - 0.11 12.7 0.1 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal CWC25 PF12542.3 EPE25186.1 - 6.9e-27 93.7 0.7 6.9e-27 93.7 0.5 4.0 3 3 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EPE25186.1 - 1.8e-13 50.2 7.2 1.8e-13 50.2 5.0 2.8 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3674 PF12426.3 EPE25186.1 - 0.14 11.5 0.1 0.38 10.1 0.1 1.7 1 0 0 1 1 1 0 RNA dependent RNA polymerase PCI PF01399.22 EPE25187.1 - 5.9e-19 68.3 0.6 1.6e-18 66.9 0.1 2.1 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EPE25187.1 - 1.2e-08 34.8 0.5 2.7e-08 33.6 0.2 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 EPE25187.1 - 0.00012 21.5 0.5 0.08 12.7 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EPE25187.1 - 0.0019 18.0 0.1 1.1 9.2 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPE25187.1 - 0.0042 16.8 0.7 0.048 13.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPE25187.1 - 0.0059 16.1 1.3 0.037 13.6 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPE25187.1 - 0.017 14.7 1.6 0.066 12.8 0.0 2.7 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.1 EPE25187.1 - 0.019 14.8 1.9 1.3 8.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPE25187.1 - 0.038 13.7 3.3 0.048 13.4 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ipi1_N PF12333.3 EPE25187.1 - 0.065 13.1 0.1 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Peptidase_C65 PF10275.4 EPE25188.1 - 2.8e-66 223.3 0.0 3.9e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain BPL_LplA_LipB PF03099.14 EPE25189.1 - 8.3e-09 35.5 0.0 0.00036 20.5 0.0 2.3 2 0 0 2 2 2 2 Biotin/lipoate A/B protein ligase family Erg28 PF03694.8 EPE25190.1 - 8.9e-30 102.9 1.2 1.2e-29 102.5 0.8 1.2 1 0 0 1 1 1 1 Erg28 like protein EOS1 PF12326.3 EPE25190.1 - 4 7.0 8.2 1.3 8.6 3.1 1.8 2 0 0 2 2 2 0 N-glycosylation protein Papilloma_E5A PF05776.7 EPE25190.1 - 4.1 7.6 6.2 6.3 7.0 0.2 2.4 2 1 0 2 2 2 0 Papillomavirus E5A protein 3Beta_HSD PF01073.14 EPE25191.1 - 2e-48 164.5 0.0 2.4e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE25191.1 - 8.9e-25 87.4 0.0 1.4e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPE25191.1 - 1.6e-13 50.1 0.0 2.3e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EPE25191.1 - 1.5e-10 41.3 0.0 2.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPE25191.1 - 1.5e-07 30.6 0.1 1.6e-06 27.2 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EPE25191.1 - 1.4e-06 27.4 0.0 2.6e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EPE25191.1 - 0.00021 21.2 1.6 0.12 12.3 0.1 2.9 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EPE25191.1 - 0.0018 17.9 1.9 0.087 12.4 0.1 2.9 2 1 0 2 2 2 1 KR domain TPR_4 PF07721.9 EPE25191.1 - 0.13 12.7 0.3 0.32 11.5 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat SUR7 PF06687.7 EPE25192.1 - 6.9e-33 114.0 3.6 8.5e-33 113.7 2.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EPE25192.1 - 1.5 8.4 19.4 6.3 6.4 0.5 3.0 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Pyridox_oxidase PF01243.15 EPE25194.1 - 3.5e-13 49.3 0.0 2.5e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EPE25194.1 - 0.00053 19.8 0.0 0.074 12.8 0.0 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase DUF2002 PF09400.5 EPE25194.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) TRM PF02005.11 EPE25195.1 - 4.5e-107 358.2 0.0 9.8e-92 307.7 0.0 2.4 2 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EPE25195.1 - 0.0076 15.8 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EPE25195.1 - 0.071 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain RAP1 PF07218.6 EPE25196.1 - 2.4 6.1 10.7 3.4 5.6 7.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YbgT_YccB PF08173.6 EPE25197.1 - 0.46 10.3 6.8 0.8 9.5 0.2 3.0 2 0 0 2 2 2 0 Membrane bound YbgT-like protein UPF0182 PF03699.8 EPE25197.1 - 4.5 5.0 7.5 3.3 5.5 4.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) Tyrosinase PF00264.15 EPE25198.1 - 8.7e-51 173.2 2.6 1.1e-50 172.8 1.8 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Tho2 PF11262.3 EPE25199.1 - 1.5e-75 254.0 0.0 2.1e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EPE25199.1 - 4.4e-26 90.4 0.1 4e-25 87.4 0.0 2.3 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.15 EPE25200.1 - 1.5e-46 158.7 0.0 3e-46 157.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE25200.1 - 1.3e-14 54.6 1.8 1e-13 51.6 1.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EPE25200.1 - 0.0016 18.3 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.2 EPE25200.1 - 0.0028 17.4 0.1 0.042 13.6 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EPE25200.1 - 0.1 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) ERG4_ERG24 PF01222.12 EPE25201.1 - 5.1e-91 305.3 13.8 6.1e-91 305.1 9.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EPE25201.1 - 0.00091 18.5 0.3 0.0024 17.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NAD_binding_10 PF13460.1 EPE25202.1 - 3.6e-14 53.1 0.0 4.4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE25202.1 - 5.4e-06 26.0 0.0 7.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EPE25202.1 - 6.7e-06 26.4 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EPE25202.1 - 2.1e-05 23.9 0.0 2.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EPE25202.1 - 0.0004 19.1 0.0 0.00055 18.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPE25202.1 - 0.023 13.6 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.10 EPE25202.1 - 0.066 12.1 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aldolase_II PF00596.16 EPE25203.1 - 6.4e-40 136.7 0.1 8e-40 136.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain CDP-OH_P_transf PF01066.16 EPE25204.1 - 9.1e-16 58.0 3.7 9.1e-16 58.0 2.6 2.4 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Adaptin_N PF01602.15 EPE25205.1 - 1.9e-104 349.8 0.0 2.6e-104 349.4 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EPE25205.1 - 1.7e-59 199.9 5.5 3.4e-59 199.0 3.8 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EPE25205.1 - 3.4e-11 43.2 0.8 0.00017 21.8 0.1 5.2 2 1 4 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 EPE25205.1 - 0.029 14.8 0.5 0.17 12.3 0.3 2.4 1 0 0 1 1 1 0 HEAT-like repeat HEAT_PBS PF03130.11 EPE25205.1 - 0.044 14.2 0.3 1.1 9.8 0.0 3.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Alpha_adaptin_C PF02296.11 EPE25205.1 - 0.072 13.0 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain HEAT PF02985.17 EPE25205.1 - 0.1 12.7 7.0 2 8.6 0.2 4.3 5 0 0 5 5 5 0 HEAT repeat bZIP_1 PF00170.16 EPE25206.1 - 3e-09 36.6 14.1 4.4e-09 36.1 9.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EPE25206.1 - 0.0059 16.8 9.9 0.0099 16.1 6.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2205 PF10224.4 EPE25206.1 - 0.16 11.5 4.2 0.33 10.5 2.9 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) FlaC_arch PF05377.6 EPE25206.1 - 0.22 11.4 1.6 0.39 10.6 1.1 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Glutaredoxin2_C PF04399.8 EPE25206.1 - 0.36 10.4 3.6 0.71 9.4 2.5 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF972 PF06156.8 EPE25206.1 - 1.1 9.6 7.2 0.5 10.7 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF966 PF06136.8 EPE25206.1 - 1.2 8.4 8.3 1.5 8.1 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) IFP_35_N PF07334.8 EPE25206.1 - 2.4 8.2 5.7 1.3 9.0 2.0 2.0 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus bZIP_2 PF07716.10 EPE25206.1 - 2.8 7.8 18.5 8.1 6.3 12.1 2.1 1 1 1 2 2 2 0 Basic region leucine zipper APG6 PF04111.7 EPE25206.1 - 2.8 6.8 8.8 3.7 6.5 6.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RNR_inhib PF08591.5 EPE25207.1 - 4.1e-18 66.0 0.2 4.1e-18 66.0 0.1 1.9 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor Phosducin PF02114.11 EPE25208.1 - 5.8e-11 41.6 0.0 1.1e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Phosducin ADH_N PF08240.7 EPE25209.1 - 1.6e-27 95.4 0.8 3.1e-27 94.4 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE25209.1 - 4.7e-14 52.0 0.2 1.3e-09 37.6 0.1 2.6 1 1 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPE25209.1 - 0.0088 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EPE25209.1 - 0.012 16.1 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 EPE25211.1 - 6.8e-18 64.4 0.1 1e-17 63.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DctQ PF04290.7 EPE25212.1 - 0.032 14.0 7.2 0.37 10.5 0.5 3.0 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component 60KD_IMP PF02096.15 EPE25212.1 - 0.054 13.1 6.6 0.43 10.2 0.1 2.1 1 1 1 2 2 2 0 60Kd inner membrane protein EphA2_TM PF14575.1 EPE25212.1 - 1.2 9.5 0.0 1.2 9.5 0.0 2.6 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF1129 PF06570.6 EPE25212.1 - 5.7 6.1 9.4 0.35 10.1 2.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Sigma_reg_N PF13800.1 EPE25212.1 - 7.8 6.6 12.5 2.5 8.2 0.9 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal ERG4_ERG24 PF01222.12 EPE25213.1 - 1.7e-09 36.7 0.5 3e-09 35.9 0.4 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EPE25213.1 - 2.6e-09 36.7 0.0 3.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) MFS_1 PF07690.11 EPE25214.1 - 8.6e-31 106.9 35.5 8.6e-31 106.9 24.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE25214.1 - 1.3e-09 37.1 27.5 5.6e-08 31.7 19.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Na_K-ATPase PF00287.13 EPE25214.1 - 0.14 10.8 0.2 0.25 10.0 0.1 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain tRNA-synt_2 PF00152.15 EPE25215.1 - 3.5e-65 219.9 0.0 5.7e-65 219.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPE25215.1 - 2.9e-06 27.0 0.2 4e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF3391 PF11871.3 EPE25215.1 - 1.5 9.0 4.8 3.1 8.0 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) NARP1 PF12569.3 EPE25215.1 - 1.6 7.4 8.5 2.2 6.9 5.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Raptor_N PF14538.1 EPE25216.1 - 2.6e-63 212.4 0.0 4.8e-63 211.5 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EPE25216.1 - 3.6e-08 32.9 9.6 1 9.3 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPE25216.1 - 0.00015 21.5 0.1 0.83 9.4 0.0 3.5 1 1 2 3 3 3 3 Ciliary BBSome complex subunit 2, middle region DUF1900 PF08954.6 EPE25216.1 - 0.00077 18.9 0.0 2.7 7.5 0.0 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF1900) Atx10homo_assoc PF09759.4 EPE25216.1 - 0.022 14.5 0.1 0.042 13.5 0.1 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Flavi_NS1 PF00948.16 EPE25217.1 - 0.085 11.2 0.0 0.1 10.9 0.0 1.0 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 Kelch_5 PF13854.1 EPE25218.1 - 1e-33 114.7 5.4 1.8e-09 37.3 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EPE25218.1 - 3.5e-33 112.9 15.8 3.2e-08 33.5 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EPE25218.1 - 3.5e-33 113.1 8.5 9.1e-07 28.5 0.7 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EPE25218.1 - 1.7e-30 103.9 5.4 8.3e-12 44.7 1.2 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EPE25218.1 - 1.5e-28 98.0 4.5 1.5e-10 40.4 0.8 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EPE25218.1 - 1.3e-20 72.2 3.1 2.3e-08 33.4 0.4 6.4 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.9 EPE25218.1 - 0.05 12.3 0.0 0.58 8.8 0.0 2.5 2 0 0 2 2 2 0 Recombination activating protein 2 Pkinase PF00069.20 EPE25219.1 - 4.8e-38 130.8 0.0 6.5e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25219.1 - 3e-13 49.4 0.0 4.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPE25219.1 - 4.8e-05 23.1 0.0 0.0026 17.5 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPE25219.1 - 0.1 11.3 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Med3 PF11593.3 EPE25219.1 - 2.7 7.1 5.2 0.24 10.5 0.4 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF4596 PF15363.1 EPE25220.1 - 0.4 10.6 2.2 0.42 10.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) p450 PF00067.17 EPE25222.1 - 6e-53 179.9 0.0 8e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SAB PF04382.8 EPE25222.1 - 0.03 14.0 0.0 0.86 9.3 0.0 2.5 2 0 0 2 2 2 0 SAB domain NMO PF03060.10 EPE25223.1 - 3.5e-39 134.8 8.0 4.3e-37 127.9 5.5 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EPE25223.1 - 5.8e-09 35.2 1.1 9.1e-09 34.6 0.8 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EPE25223.1 - 4e-06 25.9 0.7 2.3e-05 23.4 0.5 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EPE25223.1 - 6.5e-06 25.3 0.7 9.6e-06 24.7 0.5 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EPE25223.1 - 0.046 12.8 0.3 0.066 12.2 0.2 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PTR2 PF00854.16 EPE25225.1 - 1.3e-39 136.0 15.3 5.7e-38 130.6 10.6 2.4 1 1 0 1 1 1 1 POT family UCH PF00443.24 EPE25227.1 - 6.6e-42 143.4 0.2 4.2e-35 121.1 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPE25227.1 - 1.1e-16 61.1 2.0 3e-13 49.8 0.1 2.5 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L9_N PF01281.14 EPE25228.1 - 7.3e-10 37.9 0.1 1.8e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain F_bP_aldolase PF01116.15 EPE25229.1 - 6.8e-98 327.3 0.0 7.6e-98 327.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II COP-gamma_platf PF08752.5 EPE25229.1 - 0.036 13.8 0.1 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Coatomer gamma subunit appendage platform subdomain Oxysterol_BP PF01237.13 EPE25230.1 - 2.9e-90 302.3 0.0 3.5e-90 302.0 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PIG-F PF06699.6 EPE25230.1 - 0.097 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F zf-RING_2 PF13639.1 EPE25231.1 - 1.5e-05 24.7 6.0 6.5e-05 22.6 4.2 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE25231.1 - 0.041 13.8 5.8 0.14 12.1 4.0 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HUN PF08729.5 EPE25232.1 - 0.052 13.4 0.6 0.11 12.3 0.4 1.5 1 0 0 1 1 1 0 HPC2 and ubinuclein domain ATP-synt_A PF00119.15 EPE25233.1 - 0.18 11.2 8.3 1.9 7.9 2.0 2.3 2 0 0 2 2 2 0 ATP synthase A chain SPO22 PF08631.5 EPE25234.1 - 0.095 11.7 0.2 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like AA_permease_2 PF13520.1 EPE25235.1 - 2.1e-52 178.1 56.1 2.6e-52 177.8 38.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE25235.1 - 6.8e-14 51.0 49.0 9.3e-14 50.6 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4234 PF14018.1 EPE25235.1 - 0.0055 16.4 0.1 0.0055 16.4 0.1 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF4234) DUF3405 PF11885.3 EPE25237.1 - 4.6e-206 684.8 3.6 5.5e-206 684.5 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) RRM_1 PF00076.17 EPE25238.1 - 1.3e-11 43.9 0.3 2.2e-06 27.2 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE25238.1 - 1.2e-10 41.1 0.2 8.9e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE25238.1 - 5e-06 26.2 0.0 1.3e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hira PF07569.6 EPE25238.1 - 0.038 13.1 0.0 0.96 8.6 0.0 2.3 2 0 0 2 2 2 0 TUP1-like enhancer of split Peptidase_S49_N PF08496.5 EPE25238.1 - 0.077 12.7 0.4 0.077 12.7 0.2 2.4 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Cupin_2 PF07883.6 EPE25239.1 - 1.2e-08 34.3 0.1 1.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Cupin domain DUF4437 PF14499.1 EPE25239.1 - 0.0035 16.2 0.0 0.0039 16.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) PI-PLC-X PF00388.14 EPE25240.1 - 8.6e-11 41.4 0.0 1.4e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF3596 PF12167.3 EPE25240.1 - 0.061 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) Ribosomal_L10 PF00466.15 EPE25241.1 - 0.004 17.0 0.0 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L10 Sec31 PF11549.3 EPE25241.1 - 0.03 13.9 0.1 0.072 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein transport protein SEC31 Glycos_transf_3 PF00591.16 EPE25242.1 - 1.6e-61 207.9 0.0 2.3e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EPE25242.1 - 9.3e-13 47.5 0.0 1.8e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain 2-Hacid_dh_C PF02826.14 EPE25243.1 - 4.1e-52 175.9 0.0 9.9e-52 174.6 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPE25243.1 - 1.4e-20 73.0 0.0 1.8e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPE25243.1 - 0.00046 20.0 0.2 0.00084 19.2 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3151 PF11349.3 EPE25243.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3151) Zn_clus PF00172.13 EPE25244.1 - 5.9e-09 35.6 10.8 8.8e-09 35.1 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2478 PF10649.4 EPE25244.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) Nefa_Nip30_N PF10187.4 EPE25245.1 - 1.2e-29 102.4 5.1 3e-29 101.1 3.5 1.7 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Flagellar_rod PF05149.7 EPE25245.1 - 0.07 12.3 10.3 0.12 11.5 7.1 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein Aldo_ket_red PF00248.16 EPE25246.1 - 6.2e-44 149.9 0.0 7.4e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HIT PF01230.18 EPE25247.1 - 1.1e-18 67.5 0.0 1.7e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPE25247.1 - 2.4e-05 24.5 0.0 3.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EPE25247.1 - 0.0032 17.1 0.3 0.0087 15.7 0.2 1.9 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.13 EPE25248.1 - 3.2e-10 39.8 0.0 6.6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EPE25248.1 - 4.2e-07 30.0 0.0 8.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DNA_ligase_IV PF11411.3 EPE25248.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 DNA ligase IV Ribonuc_P_40 PF08584.6 EPE25249.1 - 3.8e-28 98.3 0.0 4.1e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Ank_5 PF13857.1 EPE25250.1 - 2.5e-12 46.6 0.0 9.1e-10 38.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE25250.1 - 4e-09 36.7 0.0 8.8e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPE25250.1 - 3.5e-06 27.2 0.2 5.2e-05 23.5 0.2 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPE25250.1 - 6.3e-05 22.8 0.5 0.00049 20.0 0.3 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 EPE25250.1 - 0.0001 21.9 0.2 0.00092 18.9 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeat RNA_lig_T4_1 PF09511.5 EPE25251.1 - 2.2e-79 266.0 0.0 4.4e-79 265.0 0.0 1.5 2 0 0 2 2 2 1 RNA ligase tRNA_lig_CPD PF08302.6 EPE25251.1 - 3.3e-76 255.9 0.0 4.4e-76 255.4 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EPE25251.1 - 5.1e-55 185.8 0.0 1.1e-54 184.8 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 EPE25251.1 - 0.076 13.8 0.0 0.84 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.1 EPE25251.1 - 0.16 11.8 0.2 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fe_hyd_lg_C PF02906.9 EPE25254.1 - 2.5e-63 214.0 0.0 4.8e-63 213.0 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain HTH_Tnp_ISL3 PF13542.1 EPE25254.1 - 0.065 12.4 0.2 0.94 8.7 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 OAD_beta PF03977.8 EPE25255.1 - 0.1 11.3 0.9 0.16 10.7 0.6 1.2 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit Neurensin PF14927.1 EPE25255.1 - 0.88 8.9 4.7 4.7 6.5 3.3 2.0 1 1 0 1 1 1 0 Neurensin Aldo_ket_red PF00248.16 EPE25256.1 - 1.1e-61 208.1 0.0 1.2e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LEDGF PF11467.3 EPE25256.1 - 0.043 13.5 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) zf-C2H2 PF00096.21 EPE25257.1 - 6.2e-06 26.2 0.1 6.2e-06 26.2 0.1 1.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE25257.1 - 0.0015 18.6 2.2 0.0026 17.9 0.2 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE25257.1 - 0.0084 16.3 2.8 0.093 13.0 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-Di19 PF05605.7 EPE25257.1 - 0.46 10.6 2.9 2.8 8.1 2.0 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CAP_GLY PF01302.20 EPE25259.1 - 7.8e-17 60.7 0.1 3.8e-16 58.5 0.1 2.0 2 0 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.2 EPE25259.1 - 4.9e-12 45.1 14.6 0.00055 19.4 1.6 4.8 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE25259.1 - 2.2e-10 40.1 12.2 0.00012 21.8 1.3 4.5 3 2 0 4 4 4 3 Leucine rich repeat LRR_7 PF13504.1 EPE25259.1 - 1.6e-05 24.3 8.9 11 6.7 0.1 7.3 7 0 0 7 7 7 1 Leucine rich repeat LRR_6 PF13516.1 EPE25259.1 - 0.00011 21.8 12.5 30 5.0 1.3 7.0 6 1 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.28 EPE25259.1 - 0.00076 19.1 15.4 23 5.5 0.0 7.1 6 1 1 7 7 7 1 Leucine Rich Repeat zf-met PF12874.2 EPE25260.1 - 1.9e-05 24.6 0.6 3.9e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EPE25260.1 - 0.053 12.7 0.9 0.097 11.9 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.20 EPE25261.1 - 2e-57 194.3 0.0 2.8e-56 190.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25261.1 - 8.6e-27 93.8 0.0 4.8e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPE25261.1 - 0.00031 19.7 0.0 0.00057 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPE25261.1 - 0.00084 18.4 0.0 0.0019 17.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE25261.1 - 0.00089 19.0 0.1 0.085 12.5 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPE25261.1 - 0.027 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EPE25261.1 - 0.19 11.0 0.1 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Atx10homo_assoc PF09759.4 EPE25263.1 - 2.2e-14 53.0 0.2 1.1e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DZR PF12773.2 EPE25263.1 - 0.019 14.7 0.4 0.038 13.8 0.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.7 EPE25263.1 - 0.1 12.3 1.0 0.22 11.2 0.7 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rifin_STEVOR PF02009.11 EPE25264.1 - 0.048 13.2 1.4 0.06 12.9 1.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Adeno_PIX PF03955.9 EPE25264.1 - 0.1 13.1 4.3 0.25 11.8 2.9 1.6 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) DUF829 PF05705.9 EPE25265.1 - 3.3e-36 125.1 0.1 3.9e-36 124.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) p450 PF00067.17 EPE25266.1 - 5.9e-61 206.4 0.0 7.7e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_2 PF00152.15 EPE25267.1 - 2.4e-90 302.7 1.6 3.5e-90 302.1 1.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPE25267.1 - 1.3e-11 44.1 0.5 3.4e-11 42.8 0.1 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EPE25267.1 - 7.8e-06 25.2 1.2 0.0088 15.2 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) COX15-CtaA PF02628.10 EPE25268.1 - 6.1e-96 320.8 11.8 7.4e-96 320.5 8.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF2768 PF10966.3 EPE25268.1 - 9.5 6.4 7.8 9.3 6.4 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2768) UCH PF00443.24 EPE25270.1 - 1.2e-27 96.6 0.0 2e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPE25270.1 - 1.4e-09 37.8 0.0 1.1e-08 34.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase VHS PF00790.14 EPE25271.1 - 8.3e-40 135.6 1.3 4.6e-39 133.2 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EPE25271.1 - 3.6e-16 58.7 1.1 7.1e-16 57.8 0.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EPE25271.1 - 0.00076 18.8 11.1 0.014 14.8 0.6 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif C1_1 PF00130.17 EPE25271.1 - 0.024 14.3 2.1 0.044 13.5 1.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-DHHC PF01529.15 EPE25271.1 - 0.22 10.8 6.0 0.085 12.2 0.5 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase Foie-gras_1 PF11817.3 EPE25271.1 - 3.4 7.0 8.3 7.9 5.8 5.7 1.6 1 0 0 1 1 1 0 Foie gras liver health family 1 GTP_EFTU PF00009.22 EPE25272.1 - 3.8e-50 169.9 0.0 6.7e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EPE25272.1 - 1.5e-18 66.6 1.4 2.8e-18 65.8 1.0 1.4 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 EPE25272.1 - 1.4e-09 37.9 0.0 3.1e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPE25272.1 - 7e-08 32.4 0.0 9.2e-07 28.8 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 EPE25272.1 - 8.2e-07 29.1 0.0 2.4e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Miro PF08477.8 EPE25272.1 - 3.5e-05 24.2 0.1 0.0011 19.4 0.0 2.6 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EPE25272.1 - 0.016 14.4 0.0 1.2 8.3 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Mem_trans PF03547.13 EPE25273.1 - 0.067 11.4 2.9 0.079 11.2 2.0 1.2 1 0 0 1 1 1 0 Membrane transport protein Bax1-I PF01027.15 EPE25273.1 - 0.085 12.4 11.1 0.11 12.0 7.7 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Chordopox_A33R PF05966.7 EPE25273.1 - 0.17 10.6 3.8 4.8 5.9 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus A33R protein HlyIII PF03006.15 EPE25273.1 - 0.43 9.9 8.8 1.6 8.0 6.4 1.6 1 1 0 1 1 1 0 Haemolysin-III related DUF2417 PF10329.4 EPE25273.1 - 0.73 9.2 8.5 0.28 10.5 4.1 1.8 1 1 1 2 2 2 0 Region of unknown function (DUF2417) DUF3139 PF11337.3 EPE25273.1 - 1.8 8.9 0.0 1.8 8.9 0.0 2.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3139) DUF2306 PF10067.4 EPE25273.1 - 3.5 7.7 8.2 4.2 7.5 0.5 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) YrhC PF14143.1 EPE25273.1 - 4.7 7.2 7.3 0.27 11.2 0.7 2.1 2 1 0 2 2 2 0 YrhC-like protein VCBS PF13517.1 EPE25275.1 - 1.1e-24 86.5 34.7 2.2e-08 34.3 3.3 5.2 1 1 3 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.1 EPE25275.1 - 8e-18 65.1 0.2 1.9e-17 64.0 0.2 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.18 EPE25275.1 - 3.3e-15 55.2 14.8 0.0045 16.6 0.0 5.7 5 0 0 5 5 5 5 FG-GAP repeat Lipase_GDSL PF00657.17 EPE25275.1 - 3.9e-15 56.3 0.1 6.2e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EPE25275.1 - 5.1e-06 26.3 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 EPE25275.1 - 4.9e-05 22.8 4.8 0.64 9.4 0.0 4.5 5 0 0 5 5 5 2 Insecticide toxin TcdB middle/N-terminal region Aspzincin_M35 PF14521.1 EPE25275.1 - 0.00011 22.7 0.2 0.00075 20.0 0.2 2.3 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase PAGK PF15284.1 EPE25275.1 - 0.2 11.4 0.9 0.41 10.4 0.6 1.5 1 0 0 1 1 1 0 Phage-encoded virulence factor Hamartin PF04388.7 EPE25276.1 - 0.017 13.8 5.1 0.019 13.6 3.6 1.0 1 0 0 1 1 1 0 Hamartin protein DUF1675 PF07897.6 EPE25276.1 - 2.6 7.8 9.8 3.3 7.5 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Sigma70_ner PF04546.8 EPE25276.1 - 2.8 7.4 10.1 3.5 7.1 7.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region MRI PF15325.1 EPE25276.1 - 3.2 8.7 10.8 13 6.7 5.9 2.5 1 1 1 2 2 2 0 Modulator of retrovirus infection Imm7 PF15588.1 EPE25277.1 - 0.0098 15.9 0.1 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Immunity protein 7 Baculo_RING PF05883.6 EPE25277.1 - 0.086 12.6 0.2 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain F-box-like PF12937.2 EPE25279.1 - 0.0014 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE25279.1 - 0.0022 17.5 0.0 0.0051 16.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain Zn_clus PF00172.13 EPE25280.1 - 0.023 14.6 14.6 0.042 13.7 10.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pneumo_phosprot PF02478.11 EPE25280.1 - 0.2 11.1 0.3 0.55 9.7 0.0 1.8 2 0 0 2 2 2 0 Pneumovirus phosphoprotein MFS_1 PF07690.11 EPE25281.1 - 1.1e-41 142.7 51.9 3.9e-41 140.9 34.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE25281.1 - 1.3e-12 46.7 26.1 4e-12 45.1 18.1 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE25281.1 - 9.7e-11 40.8 7.2 9.7e-11 40.8 5.0 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter Pam17 PF08566.5 EPE25281.1 - 1.5 8.5 3.3 0.63 9.7 0.2 1.9 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Glyco_transf_8 PF01501.15 EPE25282.1 - 0.00052 19.4 3.1 0.0018 17.6 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EPE25282.1 - 0.0066 15.8 0.1 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Zn_clus PF00172.13 EPE25284.1 - 7.3e-09 35.3 12.8 1.5e-08 34.4 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EPE25285.1 - 5.1e-19 68.5 0.0 1.6e-17 63.6 0.0 2.6 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EPE25285.1 - 0.00043 19.2 0.0 0.0034 16.2 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 EPE25285.1 - 0.0049 16.7 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE25285.1 - 0.0061 16.5 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPE25285.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE25285.1 - 0.13 12.7 0.0 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sulf_transp PF04143.9 EPE25286.1 - 3.9e-11 42.7 25.5 1.1e-07 31.7 7.6 5.3 5 0 0 5 5 5 2 Sulphur transport DUF4341 PF14241.1 EPE25286.1 - 7.7e-05 22.3 2.3 7.7e-05 22.3 1.6 4.4 4 2 0 4 4 4 1 Domain of unknown function (DUF4341) LAMTOR PF15454.1 EPE25288.1 - 9.7e-21 73.8 0.2 2.6e-20 72.4 0.0 1.7 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator F-box PF00646.28 EPE25290.1 - 1.1e-07 31.3 0.1 1.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE25290.1 - 4.6e-07 29.4 0.7 7e-07 28.8 0.5 1.3 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EPE25290.1 - 0.11 12.5 0.1 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 PRANC domain UPF0542 PF15086.1 EPE25291.1 - 0.25 11.1 0.8 0.71 9.6 0.5 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 HET PF06985.6 EPE25292.1 - 3.4e-22 79.0 5.1 6.3e-19 68.5 0.5 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Acyl_transf_1 PF00698.16 EPE25293.1 - 1.2e-66 225.2 0.0 1.8e-66 224.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EPE25293.1 - 2e-62 210.9 0.1 4.2e-62 209.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EPE25293.1 - 6.3e-59 198.6 0.0 3.7e-58 196.1 0.0 2.4 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EPE25293.1 - 2.4e-56 191.0 1.9 3.8e-56 190.4 1.3 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EPE25293.1 - 2.7e-46 157.5 2.2 1.9e-44 151.5 0.0 3.9 5 0 0 5 5 5 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPE25293.1 - 1.2e-37 128.3 0.0 4.2e-37 126.6 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EPE25293.1 - 6.2e-16 58.1 0.0 8.8e-15 54.4 0.0 2.8 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EPE25293.1 - 1.3e-15 57.6 0.0 3.5e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE25293.1 - 2e-10 40.6 0.0 5e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EPE25293.1 - 8.5e-10 38.3 0.8 4.8e-09 35.9 0.5 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.1 EPE25293.1 - 2.6e-09 36.8 0.0 6.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE25293.1 - 4.5e-09 36.6 0.0 3.4e-08 33.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EPE25293.1 - 2.3e-08 34.9 0.0 7.9e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EPE25293.1 - 3.3e-08 34.1 0.0 9.7e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EPE25293.1 - 9.7e-08 32.1 0.1 2.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EPE25293.1 - 0.0054 15.8 0.0 0.093 11.8 0.0 2.7 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.10 EPE25293.1 - 0.016 14.1 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NodS PF05401.6 EPE25293.1 - 0.054 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) 2OG-FeII_Oxy PF03171.15 EPE25294.1 - 2.4e-10 40.5 0.0 3.7e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EPE25294.1 - 0.07 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal CAP_N PF01213.14 EPE25294.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Myb_DNA-bind_6 PF13921.1 EPE25295.1 - 6e-29 99.9 9.3 1.9e-13 50.3 0.6 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPE25295.1 - 1.9e-20 72.6 14.7 7.6e-09 35.4 0.3 3.4 4 0 0 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EPE25295.1 - 5.7e-05 22.9 4.6 0.045 13.6 1.6 2.7 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.1 EPE25295.1 - 0.02 14.7 9.9 1.5 8.7 0.0 4.4 2 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EPE25295.1 - 0.072 13.2 5.0 7 6.9 0.1 3.1 2 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like p450 PF00067.17 EPE25296.1 - 2.3e-59 201.1 0.0 3e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EPE25297.1 - 2.2e-13 50.4 0.0 4.5e-13 49.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE25297.1 - 4.3e-06 26.5 0.0 7.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE25297.1 - 0.00016 21.5 0.0 0.00021 21.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_4 PF01565.18 EPE25298.1 - 3.5e-21 75.1 1.9 5.4e-21 74.5 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE25298.1 - 6.9e-08 32.2 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Dabb PF07876.7 EPE25299.1 - 2.7e-08 34.1 0.3 3.2e-07 30.6 0.2 1.9 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain NAD_binding_10 PF13460.1 EPE25300.1 - 1.5e-09 38.1 0.0 1.9e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPE25300.1 - 7.2e-05 21.8 0.0 0.15 10.9 0.0 2.2 1 1 0 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.19 EPE25300.1 - 0.00065 20.0 0.0 0.0022 18.2 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EPE25300.1 - 0.00089 19.1 0.1 0.0018 18.2 0.1 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EPE25300.1 - 0.0046 15.8 0.0 0.031 13.1 0.0 2.1 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EPE25300.1 - 0.0082 15.0 0.1 0.029 13.2 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Saccharop_dh PF03435.13 EPE25300.1 - 0.0097 14.9 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase MFS_1 PF07690.11 EPE25301.1 - 5.3e-40 137.2 51.9 6.7e-40 136.8 34.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 EPE25302.1 - 5.2e-52 176.9 0.0 8.1e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4511 PF14974.1 EPE25302.1 - 0.14 11.9 0.0 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4511) DUF3500 PF12006.3 EPE25303.1 - 1.8e-86 289.9 0.0 2.1e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAA_hydrolase PF01557.13 EPE25304.1 - 4.6e-53 179.8 0.0 6.2e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Polysacc_deac_1 PF01522.16 EPE25305.1 - 6.1e-12 45.2 0.0 9.8e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase HSP70 PF00012.15 EPE25306.1 - 4.5e-265 880.2 14.8 5.2e-265 880.0 10.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPE25306.1 - 5.1e-19 68.0 2.2 1.1e-17 63.5 0.5 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EPE25306.1 - 0.0022 17.1 2.8 0.046 12.8 0.1 3.1 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Ppx-GppA PF02541.11 EPE25306.1 - 0.019 14.1 0.3 0.019 14.1 0.2 1.8 2 0 0 2 2 2 0 Ppx/GppA phosphatase family FtsA PF14450.1 EPE25306.1 - 0.14 12.0 5.7 0.71 9.7 0.1 3.3 2 2 0 2 2 2 0 Cell division protein FtsA HET PF06985.6 EPE25307.1 - 3.4e-07 30.4 0.0 5.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Caps_synth_CapC PF14102.1 EPE25307.1 - 0.083 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Capsule biosynthesis CapC EST1_DNA_bind PF10373.4 EPE25308.1 - 3.9e-12 45.9 0.0 1.8e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Tcp11 PF05794.8 EPE25308.1 - 1.1e-06 27.6 0.1 1.8e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 T-complex protein 11 Ehbp PF10622.4 EPE25308.1 - 0.034 14.1 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) CorA PF01544.13 EPE25310.1 - 8.3e-07 28.3 13.8 2.2e-06 26.9 9.6 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2972 PF11186.3 EPE25310.1 - 0.046 13.6 0.8 0.53 10.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) DUF4017 PF13209.1 EPE25310.1 - 0.14 11.9 1.8 0.2 11.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) DUF21 PF01595.15 EPE25311.1 - 4.6e-30 104.2 0.0 7.5e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EPE25311.1 - 3.4e-07 29.9 0.5 0.036 13.8 0.0 2.9 3 0 0 3 3 3 2 CBS domain T4_Gp59_C PF08994.5 EPE25311.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Ribosomal_L4 PF00573.17 EPE25311.1 - 4.2 6.7 7.7 0.094 12.0 0.4 1.8 2 0 0 2 2 2 0 Ribosomal protein L4/L1 family CorA PF01544.13 EPE25312.1 - 1.2e-07 31.0 0.0 2.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein p450 PF00067.17 EPE25313.1 - 1.2e-26 93.2 0.0 6.7e-26 90.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 zf-met PF12874.2 EPE25314.1 - 0.0038 17.3 0.5 0.0064 16.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPE25314.1 - 0.012 15.7 0.2 0.022 14.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EPE25314.1 - 0.022 14.8 0.2 0.022 14.8 0.1 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3505 PF12013.3 EPE25314.1 - 0.079 13.2 0.6 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) HAUS6_N PF14661.1 EPE25314.1 - 0.55 9.5 7.4 0.95 8.7 5.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PA26 PF04636.8 EPE25314.1 - 3.6 6.1 5.6 5.4 5.5 3.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) V_ATPase_I PF01496.14 EPE25314.1 - 6.6 4.4 5.7 8.8 4.0 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hex_IIIa PF02455.11 EPE25314.1 - 8.9 4.8 7.4 1.5 7.4 2.8 1.4 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) SPOC PF07744.8 EPE25315.1 - 2.3e-18 66.8 0.0 5.3e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 EPE25315.1 - 6.6e-17 61.6 0.6 2.1e-16 59.9 0.4 1.9 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 EPE25315.1 - 2.5e-06 27.0 7.6 5.6e-06 25.9 5.2 1.5 1 0 0 1 1 1 1 PHD-finger TFIIA PF03153.8 EPE25316.1 - 0.0058 16.5 7.2 0.0095 15.8 5.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EPE25316.1 - 2.8 6.0 14.7 4.2 5.5 10.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 EPE25317.1 - 1.3e-24 86.6 51.5 1e-23 83.6 29.3 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EPE25317.1 - 2.2e-05 22.8 22.0 0.00021 19.6 15.2 2.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF543 PF04418.7 EPE25317.1 - 9.7 6.2 6.9 16 5.5 0.5 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF543) DUF673 PF05054.7 EPE25318.1 - 0.036 12.6 0.0 0.046 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF673) MFS_1 PF07690.11 EPE25319.1 - 1.3e-33 116.2 23.2 1.3e-33 116.2 16.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EPE25320.1 - 4e-54 183.8 0.0 5.5e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 EPE25321.1 - 4.1e-52 177.1 54.8 5.1e-52 176.8 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE25321.1 - 3.6e-22 78.3 43.3 4.8e-22 77.9 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EPE25325.1 - 1e-30 106.6 29.0 1e-30 106.6 20.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily ECSIT PF06239.6 EPE25326.1 - 0.092 11.5 0.3 0.17 10.7 0.2 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Zip PF02535.17 EPE25327.1 - 6.4e-44 150.2 9.1 3.5e-43 147.8 6.3 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Abhydrolase_6 PF12697.2 EPE25327.1 - 0.0022 17.8 0.1 0.0039 17.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cation_efflux PF01545.16 EPE25328.1 - 1.7e-36 125.7 9.5 2.2e-36 125.4 6.6 1.1 1 0 0 1 1 1 1 Cation efflux family AJAP1_PANP_C PF15298.1 EPE25329.1 - 0.0092 15.8 4.8 0.0092 15.8 3.3 1.7 2 0 0 2 2 2 1 AJAP1/PANP C-terminus Herpes_gE PF02480.11 EPE25329.1 - 0.037 12.3 0.2 0.051 11.8 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.1 EPE25329.1 - 0.18 11.9 2.6 0.15 12.2 0.3 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator ADH_zinc_N PF00107.21 EPE25330.1 - 1e-21 76.8 0.3 1.5e-21 76.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE25330.1 - 1.1e-12 49.0 0.1 4.2e-12 47.0 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE25330.1 - 5e-05 23.0 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EPE25330.1 - 0.025 14.1 0.1 0.025 14.1 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 EPE25330.1 - 0.036 14.0 0.3 0.063 13.2 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding Med7 PF05983.6 EPE25331.1 - 5.6e-57 192.0 0.1 6.4e-57 191.8 0.1 1.0 1 0 0 1 1 1 1 MED7 protein PAP2 PF01569.16 EPE25332.1 - 4.1e-24 84.6 1.3 9.6e-24 83.5 0.9 1.6 1 0 0 1 1 1 1 PAP2 superfamily RseC_MucC PF04246.7 EPE25332.1 - 0.0068 15.9 0.2 0.13 11.8 0.1 2.5 2 1 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC YhhN PF07947.9 EPE25332.1 - 5.8 6.2 8.5 0.31 10.4 0.3 2.3 3 0 0 3 3 3 0 YhhN-like protein FokI_N PF02981.10 EPE25333.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain Pox_A_type_inc PF04508.7 EPE25333.1 - 7.5 6.6 12.1 14 5.8 0.1 4.6 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Proteasome PF00227.21 EPE25335.1 - 6.8e-61 204.8 0.2 8.2e-61 204.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPE25335.1 - 1.8e-14 52.7 0.3 7.1e-14 50.8 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EPE25335.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit WW PF00397.21 EPE25336.1 - 2.6e-08 33.5 3.9 2.6e-08 33.5 2.7 3.0 4 0 0 4 4 4 1 WW domain FF PF01846.14 EPE25336.1 - 8.5e-07 28.8 12.9 3.7e-06 26.7 0.1 3.9 4 0 0 4 4 4 3 FF domain Tyrosinase PF00264.15 EPE25338.1 - 7.8e-55 186.4 0.7 1.1e-54 185.9 0.5 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase RNA_pol_Rpb2_6 PF00562.23 EPE25339.1 - 1.8e-112 375.9 0.1 2.4e-112 375.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPE25339.1 - 6.8e-30 103.5 0.0 1e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EPE25339.1 - 5.9e-26 91.0 0.0 1e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EPE25339.1 - 3.4e-25 87.5 0.0 7.8e-25 86.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EPE25339.1 - 1.1e-22 79.7 0.0 2.3e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EPE25339.1 - 6.1e-13 48.8 0.0 1.8e-12 47.3 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EPE25339.1 - 3.7e-05 23.6 0.0 9.1e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Arf PF00025.16 EPE25340.1 - 5.1e-44 149.5 0.0 5.9e-44 149.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EPE25340.1 - 9.2e-19 67.3 0.0 1.1e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE25340.1 - 3.8e-10 40.2 0.0 6.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EPE25340.1 - 4.7e-07 29.2 0.0 5.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPE25340.1 - 8.5e-06 25.0 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EPE25340.1 - 3e-05 22.8 0.5 0.00012 20.9 0.1 2.0 2 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EPE25340.1 - 7.9e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPE25340.1 - 0.00024 20.5 0.0 0.004 16.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EPE25340.1 - 0.012 15.3 0.0 0.1 12.4 0.1 2.0 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.13 EPE25340.1 - 0.026 13.8 0.4 0.11 11.8 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EPE25340.1 - 0.077 12.4 0.1 0.33 10.4 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RCR PF12273.3 EPE25341.1 - 2.9e-28 99.0 7.0 3.7e-28 98.6 4.8 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 EPE25341.1 - 0.00021 20.9 1.7 0.00028 20.5 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) LysE PF01810.13 EPE25341.1 - 0.027 13.7 0.1 0.036 13.3 0.1 1.1 1 0 0 1 1 1 0 LysE type translocator Rhabdo_glycop PF00974.13 EPE25341.1 - 0.052 11.7 0.5 0.072 11.3 0.4 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF1180 PF06679.7 EPE25341.1 - 3.4 7.5 5.1 1 9.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Corona_S2 PF01601.11 EPE25342.1 - 0.018 13.2 13.7 0.023 12.7 9.5 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein GP41 PF00517.12 EPE25342.1 - 0.75 9.3 1.5 1.1 8.7 1.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Pil1 PF13805.1 EPE25343.1 - 6.9e-106 353.3 5.8 9e-106 352.9 4.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Mur_ligase_C PF02875.16 EPE25343.1 - 0.06 13.3 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain APG6 PF04111.7 EPE25343.1 - 0.86 8.5 5.3 1.8 7.5 2.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 GFO_IDH_MocA PF01408.17 EPE25344.1 - 5.2e-14 52.7 0.0 8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ank_2 PF12796.2 EPE25345.1 - 5.2e-21 74.7 0.0 1.6e-08 34.7 0.0 3.6 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPE25345.1 - 6.9e-15 54.0 0.0 0.0078 15.9 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EPE25345.1 - 6.3e-13 48.8 0.0 0.00021 21.7 0.0 5.1 3 3 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE25345.1 - 2.6e-11 42.6 0.0 1.7 9.1 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EPE25345.1 - 3.3e-11 43.0 0.0 0.0051 17.0 0.0 4.9 4 1 2 6 6 6 2 Ankyrin repeats (many copies) ADH_N PF08240.7 EPE25345.1 - 9.7e-07 28.5 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peptidase_S8 PF00082.17 EPE25348.1 - 1.9e-11 43.6 0.0 3.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Pkinase PF00069.20 EPE25349.1 - 2.6e-43 148.0 0.0 4.6e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25349.1 - 8.7e-23 80.6 0.0 1.3e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EPE25349.1 - 1.3e-08 34.8 0.5 3.6e-08 33.3 0.4 1.8 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EPE25349.1 - 4.9e-05 22.4 0.0 0.00051 19.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPE25349.1 - 0.02 13.9 0.1 0.055 12.5 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPE25349.1 - 0.028 13.7 0.1 0.21 10.9 0.1 2.1 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 EPE25349.1 - 0.036 12.8 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NPV_P10 PF05531.7 EPE25351.1 - 0.044 14.0 0.0 7.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Phyto_Pns9_10 PF05878.6 EPE25352.1 - 0.04 12.9 0.0 0.057 12.4 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Acetyltransf_3 PF13302.1 EPE25353.1 - 4.7e-19 68.9 0.0 7.3e-19 68.3 0.0 1.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPE25353.1 - 9.1e-05 22.4 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE25353.1 - 0.0023 17.9 0.1 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE25353.1 - 0.02 15.0 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2527 PF10736.4 EPE25353.1 - 0.15 11.6 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) E1-E2_ATPase PF00122.15 EPE25354.1 - 3.4e-48 163.6 0.1 1.9e-47 161.2 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPE25354.1 - 7e-41 140.9 0.1 1.5e-40 139.9 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EPE25354.1 - 1.1e-36 124.7 0.6 1.5e-10 41.0 0.2 4.8 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EPE25354.1 - 1.2e-15 58.1 0.0 2.6e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPE25354.1 - 0.00017 21.2 0.2 0.0037 16.8 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2589 PF11655.3 EPE25356.1 - 0.097 12.7 0.1 5.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2589) Fil_haemagg_2 PF13332.1 EPE25356.1 - 0.2 11.4 0.1 0.2 11.4 0.1 2.6 3 0 0 3 3 3 0 Haemagluttinin repeat DUF1996 PF09362.5 EPE25357.1 - 9.9e-52 175.9 0.0 1.3e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Methyltransf_23 PF13489.1 EPE25358.1 - 2.9e-09 36.8 0.0 5.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE25358.1 - 3.2e-08 33.9 0.0 5.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE25358.1 - 2.7e-07 30.9 0.0 4.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE25358.1 - 8.7e-07 29.5 0.0 2e-06 28.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE25358.1 - 9.1e-06 25.3 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE25358.1 - 0.00076 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE25358.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.7 EPE25358.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase DUF938 PF06080.7 EPE25358.1 - 0.021 14.3 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 EPE25358.1 - 0.036 14.0 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EPE25358.1 - 0.04 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.4 EPE25358.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 EPE25358.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF3328 PF11807.3 EPE25360.1 - 7.4e-34 117.3 0.7 9e-34 117.0 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EPE25361.1 - 3.2e-47 160.9 30.1 3.2e-47 160.9 20.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE25361.1 - 1.2e-11 43.9 10.3 1.2e-11 43.9 7.1 3.1 1 1 1 2 2 2 1 Sugar (and other) transporter Amidohydro_1 PF01979.15 EPE25362.1 - 4.5e-33 115.2 0.5 5.7e-33 114.9 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EPE25362.1 - 2.1e-19 70.6 0.9 2.4e-17 63.8 0.6 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EPE25362.1 - 1.8e-11 43.6 0.2 5.5e-11 42.1 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPE25362.1 - 2.7e-08 33.4 6.1 6.3e-06 25.6 1.1 2.3 1 1 1 2 2 2 2 Amidohydrolase family Fungal_trans_2 PF11951.3 EPE25363.1 - 4e-40 137.5 0.1 5e-40 137.2 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE25363.1 - 2.4e-09 36.9 6.0 2.4e-09 36.9 4.2 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.16 EPE25364.1 - 2.9e-55 187.4 0.0 3.7e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III CBP4 PF07960.6 EPE25365.1 - 0.3 10.7 0.0 0.3 10.7 0.0 2.8 2 1 0 2 2 2 0 CBP4 MIT PF04212.13 EPE25366.1 - 0.094 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Peptidase_S8 PF00082.17 EPE25367.1 - 8.9e-17 61.1 0.0 1.7e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Mito_fiss_reg PF05308.6 EPE25367.1 - 0.039 13.3 1.7 0.078 12.3 1.2 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Amidase PF01425.16 EPE25370.1 - 6.6e-96 321.8 0.0 7.9e-96 321.5 0.0 1.1 1 0 0 1 1 1 1 Amidase 2OG-FeII_Oxy_2 PF13532.1 EPE25371.1 - 2.3e-33 115.6 0.0 7.1e-33 114.0 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EPE25372.1 - 5.1e-73 245.4 0.0 6.3e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25372.1 - 5.7e-32 110.7 0.0 7.2e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE25372.1 - 0.0019 17.2 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPE25372.1 - 0.0088 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPE25372.1 - 0.016 14.0 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EPE25372.1 - 0.082 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TH1 PF04858.8 EPE25373.1 - 0.02 13.0 0.0 0.026 12.6 0.0 1.1 1 0 0 1 1 1 0 TH1 protein REV PF00424.13 EPE25373.1 - 0.043 13.6 2.1 0.043 13.6 1.4 2.3 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) HET PF06985.6 EPE25374.1 - 7.1e-29 100.7 0.2 3.7e-27 95.1 0.2 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyoxalase PF00903.20 EPE25375.1 - 4.4e-05 23.4 0.0 7.5e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EPE25375.1 - 0.00018 22.1 0.0 0.00022 21.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain HET PF06985.6 EPE25376.1 - 1.5e-23 83.4 0.0 2.5e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EPE25378.1 - 6.3e-25 87.9 4.1 9.8e-25 87.3 2.8 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.19 EPE25379.1 - 7e-77 258.9 25.9 8.2e-77 258.6 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE25379.1 - 2.5e-29 102.1 35.6 2.4e-21 75.8 11.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Tri3 PF07428.6 EPE25380.1 - 7.3e-06 24.9 0.1 9.5e-05 21.2 0.0 2.4 2 1 0 2 2 2 1 15-O-acetyltransferase Tri3 AATase PF07247.7 EPE25380.1 - 0.0046 15.5 0.0 0.0079 14.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EPE25380.1 - 0.061 12.1 0.0 2.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Condensation domain ketoacyl-synt PF00109.21 EPE25381.1 - 1.6e-69 234.2 0.1 3.6e-69 233.0 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPE25381.1 - 2.2e-58 198.0 0.0 3.7e-58 197.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EPE25381.1 - 6e-50 170.0 0.0 1.3e-49 168.9 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EPE25381.1 - 8.1e-48 162.4 0.0 2.8e-47 160.7 0.0 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EPE25381.1 - 8.9e-42 142.8 0.0 1.5e-40 138.8 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPE25381.1 - 2e-36 124.4 0.1 6.6e-36 122.7 0.1 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EPE25381.1 - 2.5e-18 66.3 0.0 1.2e-17 64.2 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EPE25381.1 - 1.2e-16 60.4 1.0 8.8e-16 57.6 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EPE25381.1 - 5.2e-12 45.7 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE25381.1 - 3e-09 37.4 0.0 3.4e-08 34.0 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE25381.1 - 4.6e-09 36.6 0.0 1.9e-08 34.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EPE25381.1 - 1.3e-08 35.7 0.0 1.8e-07 32.0 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EPE25381.1 - 1.4e-06 27.9 0.0 3.4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE25381.1 - 1.1e-05 25.7 0.0 5.8e-05 23.3 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE25381.1 - 1.1e-05 24.6 0.0 3.6e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EPE25381.1 - 1.3e-05 25.3 0.4 5.8e-05 23.2 0.2 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EPE25381.1 - 0.00027 20.6 0.0 0.00058 19.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PCMT PF01135.14 EPE25381.1 - 0.0022 17.5 0.1 0.17 11.4 0.0 2.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LEM PF03020.10 EPE25381.1 - 0.01 15.2 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 LEM domain Zn_clus PF00172.13 EPE25382.1 - 3.3e-06 26.8 9.2 3.3e-06 26.8 6.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.4 EPE25382.1 - 0.064 13.0 6.8 0.19 11.5 0.3 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Transferase PF02458.10 EPE25383.1 - 5.1e-11 41.6 0.0 5.4e-08 31.6 0.0 3.1 2 1 0 2 2 2 2 Transferase family p450 PF00067.17 EPE25384.1 - 3e-65 220.5 0.0 3.8e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UDPGT PF00201.13 EPE25385.1 - 4.9e-05 22.0 0.0 6.6e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Mito_fiss_Elm1 PF06258.6 EPE25385.1 - 0.0042 16.0 0.1 0.021 13.8 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial fission ELM1 Rap1_C PF11626.3 EPE25386.1 - 2.2e-20 72.3 2.8 8.9e-20 70.3 0.1 3.0 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EPE25386.1 - 8.2e-20 70.3 3.5 7.4e-16 57.7 0.2 2.9 2 1 0 2 2 2 2 Rap1 Myb domain ARID PF01388.16 EPE25386.1 - 4.1e-14 52.1 0.0 9.5e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Rap1-DNA-bind PF09197.5 EPE25386.1 - 4.7e-08 33.5 11.2 1.2e-05 25.8 0.0 4.2 4 1 1 5 5 5 2 Rap1, DNA-binding Myb_DNA-bind_6 PF13921.1 EPE25386.1 - 2.6 8.2 10.2 3.2 7.9 1.9 4.2 4 1 1 5 5 5 0 Myb-like DNA-binding domain Neur_chan_memb PF02932.11 EPE25386.1 - 6.8 6.4 5.3 2.6 7.8 1.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-DHHC PF01529.15 EPE25387.1 - 2.5e-33 114.9 8.9 2.5e-33 114.9 6.2 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Fungal_trans_2 PF11951.3 EPE25388.1 - 3.4e-14 52.2 1.5 5.5e-14 51.5 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE25388.1 - 0.0045 16.8 7.2 0.0073 16.1 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ytp1 PF10355.4 EPE25389.1 - 3.8e-90 301.7 21.3 2.2e-85 286.1 4.4 2.7 2 1 1 3 3 3 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EPE25389.1 - 1.3e-23 82.5 2.8 1.3e-23 82.5 2.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) DUF1129 PF06570.6 EPE25389.1 - 0.015 14.5 0.2 0.015 14.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) zf-Di19 PF05605.7 EPE25390.1 - 0.017 15.2 0.2 0.049 13.7 0.1 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF4503 PF14951.1 EPE25390.1 - 0.18 9.8 0.0 0.41 8.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4503) zf-C2H2_2 PF12756.2 EPE25391.1 - 6.8e-32 109.5 22.0 8e-30 102.9 0.6 3.9 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EPE25391.1 - 1.7e-06 28.0 3.5 0.00015 21.7 0.8 4.6 5 1 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPE25391.1 - 0.00044 20.3 7.7 0.0012 18.9 0.6 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type AKAP95 PF04988.7 EPE25391.1 - 0.0034 17.1 2.1 2.8 7.7 0.0 3.2 2 1 1 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 EPE25391.1 - 0.011 15.9 13.5 0.56 10.6 0.2 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE25391.1 - 0.097 13.0 19.0 0.26 11.7 0.3 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2HC5 PF06221.8 EPE25391.1 - 0.4 10.4 2.8 24 4.7 0.1 3.4 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-C2H2_6 PF13912.1 EPE25391.1 - 0.42 10.5 0.1 0.42 10.5 0.1 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger HECT PF00632.20 EPE25392.1 - 1.2e-72 244.8 0.0 1.6e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Mitofilin PF09731.4 EPE25392.1 - 4.4 5.8 4.8 6.5 5.2 3.3 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2207 PF09972.4 EPE25394.1 - 0.43 9.1 2.3 0.54 8.7 1.0 1.5 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SdpI PF13630.1 EPE25394.1 - 6.6 6.5 7.9 12 5.7 5.4 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family Zn_clus PF00172.13 EPE25395.1 - 6.1 6.8 8.4 26 4.8 2.1 3.0 1 1 2 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EPE25396.1 - 0.003 17.4 8.8 0.0054 16.6 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EPE25396.1 - 0.14 11.9 0.0 0.98 9.2 0.0 2.2 2 0 0 2 2 2 0 PAS fold MFS_1 PF07690.11 EPE25398.1 - 4e-44 150.7 27.2 4e-44 150.7 18.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE25398.1 - 1.7e-09 36.4 2.0 1.7e-09 36.4 1.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Flavokinase PF01687.12 EPE25399.1 - 5.3e-33 113.5 0.0 1.8e-31 108.6 0.0 2.1 1 1 0 1 1 1 1 Riboflavin kinase DUF3958 PF13125.1 EPE25400.1 - 0.038 13.8 0.1 0.092 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Apolipoprotein PF01442.13 EPE25400.1 - 0.08 12.4 0.7 0.18 11.3 0.5 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain GAS PF13851.1 EPE25400.1 - 1.5 7.9 4.5 0.44 9.7 0.6 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding AA_permease_2 PF13520.1 EPE25401.1 - 2.4e-55 187.8 32.3 1.1e-53 182.3 22.4 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE25401.1 - 6.8e-12 44.4 24.1 6.8e-12 44.4 16.7 2.9 2 1 0 2 2 2 1 Amino acid permease Aa_trans PF01490.13 EPE25402.1 - 5.5e-31 107.4 28.1 6.4e-31 107.2 19.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2453 PF10507.4 EPE25402.1 - 0.0047 16.7 1.7 1.1 9.0 0.1 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF2453) NACHT PF05729.7 EPE25403.1 - 8.2e-10 38.5 0.0 2.6e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EPE25403.1 - 2.8e-05 24.2 1.9 0.001 19.2 0.0 3.3 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EPE25403.1 - 0.0039 17.5 0.4 0.096 12.9 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.1 EPE25403.1 - 0.021 15.1 0.1 0.15 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EPE25403.1 - 0.053 14.3 0.0 0.48 11.2 0.0 2.8 1 1 0 1 1 1 0 AAA domain HMG-CoA_red PF00368.13 EPE25403.1 - 0.064 11.9 0.4 0.13 10.9 0.3 1.4 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase Exo_endo_phos PF03372.18 EPE25404.1 - 3.5e-08 33.6 0.8 6.5e-08 32.8 0.6 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 EPE25404.1 - 4.7e-05 23.2 0.1 0.00013 21.8 0.0 1.8 1 1 1 2 2 2 1 Jacalin-like lectin domain Mur_ligase_C PF02875.16 EPE25404.1 - 0.055 13.5 0.1 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain UDPGT PF00201.13 EPE25405.1 - 0.00086 17.9 0.0 0.0075 14.8 0.0 2.0 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase B12-binding PF02310.14 EPE25406.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain ArsC PF03960.10 EPE25406.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 ArsC family VHS PF00790.14 EPE25409.1 - 3.1e-14 52.7 0.1 6.7e-14 51.7 0.0 1.6 2 0 0 2 2 2 1 VHS domain Lyase_1 PF00206.15 EPE25410.1 - 1.7e-22 80.0 0.0 2.6e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EPE25410.1 - 6.4e-16 58.1 0.0 4.3e-15 55.4 0.0 2.5 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus Fasciclin PF02469.17 EPE25412.1 - 3.9e-46 156.2 0.0 1.1e-25 90.0 0.0 2.9 3 0 0 3 3 3 2 Fasciclin domain Pyridoxal_deC PF00282.14 EPE25413.1 - 7.3e-58 195.7 0.0 1e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EPE25413.1 - 2.9e-05 22.9 0.0 6.8e-05 21.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Glyoxalase PF00903.20 EPE25415.1 - 6.8e-41 139.2 0.2 6.4e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EPE25415.1 - 3.1e-32 111.4 0.0 5.2e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EPE25415.1 - 2.8e-18 65.9 0.0 6.1e-07 29.4 0.0 3.9 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EPE25415.1 - 3.4e-07 30.3 0.0 0.031 14.1 0.0 2.8 1 1 1 2 2 2 2 Glyoxalase-like domain DUF4105 PF13387.1 EPE25415.1 - 0.0021 17.2 0.1 3.2 6.9 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4105) CppA_N PF14506.1 EPE25415.1 - 0.019 14.6 0.3 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 CppA N-terminal MoaF PF10703.4 EPE25415.1 - 0.022 13.8 0.1 0.7 8.9 0.0 2.1 2 0 0 2 2 2 0 Molybdenum cofactor biosynthesis protein F 2-Hacid_dh_C PF02826.14 EPE25416.1 - 1.7e-52 177.1 0.0 3.1e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPE25416.1 - 2.1e-35 121.0 0.3 2.3e-34 117.7 0.1 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 EPE25416.1 - 0.00017 20.9 6.0 0.0019 17.6 0.0 3.4 3 1 0 3 3 3 2 ACT domain Asparaginase PF00710.15 EPE25417.1 - 1.1e-69 234.7 4.7 1.3e-69 234.4 3.2 1.1 1 0 0 1 1 1 1 Asparaginase RHIM PF12721.2 EPE25417.1 - 9.7 6.6 8.9 0.22 11.9 0.4 2.7 4 0 0 4 4 4 0 RIP homotypic interaction motif Abhydrolase_2 PF02230.11 EPE25419.1 - 1.1e-29 103.4 0.0 3.9e-19 68.9 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EPE25419.1 - 3.6e-09 36.1 0.0 7.2e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EPE25419.1 - 3.1e-08 33.7 0.1 2.8e-07 30.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE25419.1 - 4.3e-08 33.0 0.0 6.5e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EPE25419.1 - 8.4e-06 25.1 0.0 1.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Secretory lipase Fungal_trans_2 PF11951.3 EPE25420.1 - 6.9e-05 21.6 0.1 8.7e-05 21.2 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_3 PF01596.12 EPE25421.1 - 3.2e-47 160.2 0.0 3.8e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EPE25421.1 - 6.7e-15 55.8 0.1 2.2e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE25421.1 - 1.2e-09 38.7 0.0 2.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPE25421.1 - 5.2e-09 35.9 0.0 7.8e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EPE25421.1 - 1.3e-07 31.3 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE25421.1 - 1.3e-06 28.4 0.0 2.1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPE25421.1 - 0.0013 17.9 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CmcI PF04989.7 EPE25421.1 - 0.0014 17.9 0.0 0.0031 16.8 0.0 1.4 1 1 0 1 1 1 1 Cephalosporin hydroxylase GCD14 PF08704.5 EPE25421.1 - 0.0029 17.1 0.0 0.0037 16.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.9 EPE25421.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 EPE25421.1 - 0.0092 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 EPE25421.1 - 0.043 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EPE25421.1 - 0.047 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 4HBT PF03061.17 EPE25422.1 - 7.4e-08 32.4 0.1 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily FMN_red PF03358.10 EPE25423.1 - 2.2e-24 85.7 0.0 3e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase zf-RING_2 PF13639.1 EPE25424.1 - 4.3e-10 39.2 3.6 4.3e-10 39.2 2.5 2.9 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EPE25424.1 - 1.9e-06 27.4 1.3 1.9e-06 27.4 0.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EPE25424.1 - 1.3e-05 25.1 8.1 1.5e-05 24.9 2.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE25424.1 - 2.4e-05 24.3 4.4 4.3e-05 23.5 0.3 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPE25424.1 - 3e-05 23.6 5.3 0.00011 21.8 1.3 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE25424.1 - 4.9e-05 22.9 0.9 4.9e-05 22.9 0.6 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE25424.1 - 0.00027 20.5 5.7 0.00065 19.3 1.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPE25424.1 - 0.0031 17.3 2.1 0.0031 17.3 1.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EPE25424.1 - 0.017 14.9 4.3 0.028 14.2 0.4 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.16 EPE25424.1 - 0.031 14.1 2.5 0.56 10.1 0.9 2.8 2 1 0 2 2 2 0 FYVE zinc finger RINGv PF12906.2 EPE25424.1 - 0.12 12.4 5.2 0.17 11.9 1.8 2.6 2 1 0 2 2 2 0 RING-variant domain zf-met PF12874.2 EPE25424.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF1275 PF06912.6 EPE25425.1 - 3.1e-43 147.4 8.2 3.9e-43 147.0 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MgtC PF02308.11 EPE25425.1 - 0.02 14.7 0.3 0.041 13.7 0.2 1.5 1 0 0 1 1 1 0 MgtC family ABC_tran PF00005.22 EPE25426.1 - 1.1e-48 165.0 0.1 1.5e-26 93.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPE25426.1 - 2.8e-15 57.0 2.9 0.008 16.1 0.2 4.2 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 EPE25426.1 - 2.4e-10 40.0 4.3 0.0014 17.8 0.0 4.2 3 2 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPE25426.1 - 6.8e-08 31.9 1.0 0.0028 17.1 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EPE25426.1 - 5.4e-07 30.1 2.7 0.0036 17.6 0.1 2.9 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 EPE25426.1 - 7.6e-06 26.4 0.0 0.028 14.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EPE25426.1 - 7.9e-06 25.1 0.1 0.03 13.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EPE25426.1 - 1.6e-05 24.1 0.2 0.39 9.7 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 EPE25426.1 - 2.3e-05 24.3 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EPE25426.1 - 4.5e-05 24.2 0.1 0.57 11.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain Chromo PF00385.19 EPE25426.1 - 8.6e-05 22.1 0.8 0.00025 20.6 0.3 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain SbcCD_C PF13558.1 EPE25426.1 - 9e-05 22.3 0.0 0.94 9.4 0.0 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EPE25426.1 - 0.00032 20.2 2.2 1 8.7 0.1 3.6 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 EPE25426.1 - 0.00044 20.3 0.1 0.57 10.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_13 PF13166.1 EPE25426.1 - 0.0011 17.5 0.0 0.88 7.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EPE25426.1 - 0.0012 18.8 0.0 0.086 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EPE25426.1 - 0.0014 18.4 4.0 0.51 10.1 0.5 3.5 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_33 PF13671.1 EPE25426.1 - 0.0016 18.2 0.0 0.58 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPE25426.1 - 0.0031 17.8 0.1 1.3 9.3 0.1 2.8 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EPE25426.1 - 0.0033 17.2 0.0 0.22 11.3 0.0 2.9 3 0 0 3 3 3 1 Dynamin family AAA_25 PF13481.1 EPE25426.1 - 0.0061 15.9 0.0 2.7 7.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EPE25426.1 - 0.0066 15.9 0.6 0.7 9.3 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 EPE25426.1 - 0.008 15.8 0.9 0.59 9.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EPE25426.1 - 0.012 15.8 0.5 2.3 8.4 0.0 2.9 3 0 0 3 3 2 0 RNA helicase MobB PF03205.9 EPE25426.1 - 0.026 14.2 0.4 6.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EPE25426.1 - 0.037 13.5 0.1 3.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 EPE25426.1 - 0.05 13.1 0.1 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HEAT_2 PF13646.1 EPE25426.1 - 0.059 13.6 0.6 1.8 8.8 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats AAA PF00004.24 EPE25426.1 - 0.074 13.2 0.1 5.8 7.1 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3584 PF12128.3 EPE25426.1 - 1.2 6.3 9.8 0.81 6.9 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Rifin_STEVOR PF02009.11 EPE25427.1 - 6e-05 22.8 0.1 0.0059 16.2 0.0 2.2 2 0 0 2 2 2 1 Rifin/stevor family DUF912 PF06024.7 EPE25427.1 - 8.4e-05 22.5 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 2 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_gE PF02480.11 EPE25427.1 - 9.1e-05 20.8 1.7 0.038 12.2 0.0 2.1 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E DUF4064 PF13273.1 EPE25427.1 - 0.00016 21.7 1.9 0.42 10.7 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4064) TMEM154 PF15102.1 EPE25427.1 - 0.00026 20.7 1.8 0.27 10.9 0.1 2.3 2 0 0 2 2 2 2 TMEM154 protein family DUF4448 PF14610.1 EPE25427.1 - 0.00029 20.3 0.2 0.074 12.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) IncA PF04156.9 EPE25427.1 - 0.0031 17.1 0.3 0.35 10.4 0.1 2.3 2 0 0 2 2 2 1 IncA protein EphA2_TM PF14575.1 EPE25427.1 - 0.0052 17.1 2.6 2.6 8.4 0.2 2.4 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Tetraspannin PF00335.15 EPE25427.1 - 0.0065 15.7 0.9 0.79 8.9 0.0 2.3 2 0 0 2 2 2 1 Tetraspanin family DAG1 PF05454.6 EPE25427.1 - 0.013 14.7 0.3 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TRP PF06011.7 EPE25427.1 - 0.02 13.5 1.4 0.053 12.0 0.1 1.9 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel RSN1_TM PF13967.1 EPE25427.1 - 0.58 9.7 4.4 15 5.1 0.0 2.6 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport RCR PF12273.3 EPE25427.1 - 1.6 9.3 10.1 7.6 7.1 0.6 2.7 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Rax2 PF12768.2 EPE25428.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF1517 PF07466.6 EPE25428.1 - 0.014 14.3 0.4 0.022 13.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) TMEM154 PF15102.1 EPE25429.1 - 0.00054 19.6 0.3 0.00084 19.0 0.2 1.4 1 1 0 1 1 1 1 TMEM154 protein family Protocadherin PF08374.6 EPE25429.1 - 0.018 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Protocadherin TMEM51 PF15345.1 EPE25429.1 - 0.022 14.4 0.1 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 FAM176 PF14851.1 EPE25429.1 - 0.022 14.4 0.1 0.03 14.0 0.1 1.2 1 0 0 1 1 1 0 FAM176 family EphA2_TM PF14575.1 EPE25429.1 - 0.1 13.0 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 EPE25429.1 - 0.1 11.3 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Ly49 PF08391.5 EPE25429.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region CcoS PF03597.10 EPE25429.1 - 1.8 8.1 5.2 0.5 9.8 1.1 1.8 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Chitin_bind_1 PF00187.14 EPE25430.1 - 2.9e-09 36.7 22.1 1.1e-08 34.9 15.3 2.1 1 0 0 1 1 1 1 Chitin recognition protein Chitin_bind_3 PF03067.10 EPE25430.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 1 0 1 1 1 0 Chitin binding domain Abhydrolase_6 PF12697.2 EPE25431.1 - 9.6e-32 110.6 0.0 1.2e-31 110.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE25431.1 - 4.1e-20 72.3 0.0 2.1e-19 70.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE25431.1 - 8.5e-10 38.5 0.0 6.5e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE25431.1 - 7.5e-07 28.9 0.0 1.7e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Putative lysophospholipase EHN PF06441.7 EPE25431.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DASH_Hsk3 PF08227.6 EPE25432.1 - 1.8e-21 76.0 3.1 2.4e-21 75.6 2.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like zf-CHY PF05495.7 EPE25433.1 - 2e-17 63.0 27.9 2.5e-15 56.3 10.0 3.6 3 0 0 3 3 3 2 CHY zinc finger CAF1A PF12253.3 EPE25433.1 - 0.06 13.4 3.7 0.13 12.3 2.5 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A DUF3295 PF11702.3 EPE25434.1 - 1.5e-148 496.0 36.8 1.9e-148 495.6 25.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EPE25434.1 - 1.6e-10 40.3 1.5 4.3e-10 38.9 1.0 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) HET PF06985.6 EPE25439.1 - 1.8e-24 86.4 0.0 3.7e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_2 PF00891.13 EPE25441.1 - 2.7e-38 131.5 0.0 3.6e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EPE25441.1 - 0.00021 21.8 0.0 0.0007 20.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE25441.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EPE25441.1 - 0.0015 17.8 0.1 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain DOT1 PF08123.8 EPE25441.1 - 0.0079 15.5 0.1 0.11 11.8 0.1 2.3 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 EPE25441.1 - 0.0083 16.5 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE25441.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.17 EPE25442.1 - 5.7e-55 186.6 0.0 7.5e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2642 PF10842.3 EPE25442.1 - 0.078 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) ABC2_membrane_3 PF12698.2 EPE25443.1 - 0.091 11.7 3.8 0.14 11.1 2.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein RTA1 PF04479.8 EPE25444.1 - 1.4e-40 139.2 10.3 2.1e-40 138.5 7.1 1.2 1 0 0 1 1 1 1 RTA1 like protein Glycophorin_A PF01102.13 EPE25444.1 - 0.093 12.5 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Glycophorin A DUF21 PF01595.15 EPE25444.1 - 0.44 9.8 7.9 0.035 13.3 0.7 2.3 1 1 0 2 2 2 0 Domain of unknown function DUF21 PAN_4 PF14295.1 EPE25445.1 - 0.027 14.1 1.1 0.062 13.0 0.7 1.6 1 0 0 1 1 1 0 PAN domain NAD_binding_6 PF08030.7 EPE25446.1 - 3.8e-18 65.8 0.0 5.8e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPE25446.1 - 9.5e-18 64.4 11.6 9.5e-18 64.4 8.0 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EPE25446.1 - 1.7e-11 43.9 0.0 3.1e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain Rad4 PF03835.10 EPE25447.1 - 1e-33 115.8 0.3 2.1e-33 114.7 0.2 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EPE25447.1 - 1.5e-28 98.2 0.0 3e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EPE25447.1 - 2.1e-17 62.3 0.0 4.7e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EPE25447.1 - 1.6e-11 44.3 0.1 5.9e-11 42.5 0.1 2.1 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EPE25447.1 - 0.018 15.2 0.0 0.12 12.6 0.0 2.3 1 1 0 1 1 1 0 Transglutaminase-like superfamily Ion_trans_2 PF07885.11 EPE25449.1 - 4.9e-28 96.6 23.7 3.6e-15 55.4 4.2 3.3 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.21 EPE25449.1 - 1.2 8.8 7.3 2.3 7.9 2.7 2.9 2 2 0 2 2 2 0 Ligand-gated ion channel DEAD PF00270.24 EPE25451.1 - 8.9e-42 142.4 0.0 1.5e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE25451.1 - 1.8e-22 78.9 0.0 4.9e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPE25451.1 - 0.00044 19.1 0.0 0.00067 18.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EPE25451.1 - 0.064 11.6 0.0 11 4.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) GET2 PF08690.5 EPE25451.1 - 0.42 9.8 3.1 0.73 9.0 2.2 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 RR_TM4-6 PF06459.7 EPE25451.1 - 0.45 10.3 8.5 0.95 9.2 5.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FtsJ PF01728.14 EPE25452.1 - 3.3e-61 206.4 0.0 4.2e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Mito_carr PF00153.22 EPE25453.1 - 5.6e-55 183.0 4.6 5.3e-19 67.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PEX11 PF05648.9 EPE25454.1 - 1.2e-75 253.6 0.2 1.3e-75 253.4 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Fapy_DNA_glyco PF01149.19 EPE25455.1 - 3.4e-22 78.9 0.0 8.1e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EPE25455.1 - 5.5e-22 77.3 0.0 1.1e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Mitofilin PF09731.4 EPE25455.1 - 0.29 9.7 23.1 0.41 9.2 16.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ABC2_membrane PF01061.19 EPE25456.1 - 1.2e-92 308.8 62.8 3.1e-48 163.7 17.9 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPE25456.1 - 5.3e-35 120.6 0.0 2.9e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EPE25456.1 - 1.1e-34 118.1 9.9 1.5e-31 108.1 0.0 3.7 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.1 EPE25456.1 - 1.9e-18 66.3 0.0 4.7e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EPE25456.1 - 2.5e-07 30.2 0.0 4.3e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EPE25456.1 - 3.6e-06 26.2 0.1 0.00041 19.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EPE25456.1 - 4.3e-06 26.6 0.1 0.00022 21.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPE25456.1 - 5.9e-06 26.3 0.8 0.0007 19.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EPE25456.1 - 0.00062 19.2 2.0 0.036 13.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EPE25456.1 - 0.0014 18.0 2.1 0.023 14.1 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 EPE25456.1 - 0.0026 17.0 0.0 0.19 10.9 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EPE25456.1 - 0.0028 17.9 0.1 0.22 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPE25456.1 - 0.0085 16.9 0.0 0.38 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE25456.1 - 0.0087 16.2 0.2 1.2 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EPE25456.1 - 0.019 14.9 0.0 1.6 8.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain ABC2_membrane_3 PF12698.2 EPE25456.1 - 0.029 13.4 51.4 0.32 9.9 15.7 2.9 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_19 PF13245.1 EPE25456.1 - 0.029 14.0 2.1 2.2 8.0 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EPE25456.1 - 0.036 13.7 0.8 3.7 7.1 0.3 2.6 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 EPE25456.1 - 0.046 14.2 0.0 17 5.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 EPE25456.1 - 0.064 13.2 0.4 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EPE25456.1 - 0.21 11.5 0.0 17 5.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RTA1 PF04479.8 EPE25458.1 - 9.9e-25 87.3 4.0 1.4e-24 86.8 2.8 1.2 1 0 0 1 1 1 1 RTA1 like protein Ndc1_Nup PF09531.5 EPE25458.1 - 0.37 9.1 4.2 0.74 8.1 2.9 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAS_9 PF13426.1 EPE25460.1 - 8.8e-14 51.7 0.0 1.4e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EPE25460.1 - 0.034 13.9 0.0 0.22 11.3 0.0 2.2 2 1 0 2 2 2 0 PAS fold DUF3400 PF11880.3 EPE25460.1 - 0.094 11.9 1.2 0.16 11.2 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) Rad10 PF03834.9 EPE25460.1 - 0.15 11.7 0.2 0.41 10.3 0.1 1.7 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DUF4064 PF13273.1 EPE25461.1 - 0.0062 16.6 0.6 0.013 15.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) MacB_PCD PF12704.2 EPE25461.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 MacB-like periplasmic core domain DUF1191 PF06697.7 EPE25461.1 - 0.023 13.5 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF912 PF06024.7 EPE25461.1 - 0.049 13.6 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EPE25461.1 - 0.068 12.8 0.2 0.098 12.2 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family SKG6 PF08693.5 EPE25461.1 - 0.45 9.8 6.4 1.2 8.4 4.4 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RPN7 PF10602.4 EPE25462.1 - 1.1e-57 194.2 0.8 1.7e-57 193.6 0.5 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EPE25462.1 - 5.8e-13 49.0 0.0 2.1e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 PCI domain BEX PF04538.7 EPE25462.1 - 0.11 12.7 5.9 0.19 11.9 4.1 1.4 1 0 0 1 1 1 0 Brain expressed X-linked like family TPR_7 PF13176.1 EPE25462.1 - 0.13 12.1 1.3 0.39 10.6 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pox_MCEL PF03291.11 EPE25463.1 - 2.2e-64 217.4 0.0 1.6e-42 145.5 0.0 3.5 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 EPE25463.1 - 2.1e-08 34.5 0.0 0.0096 16.3 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EPE25463.1 - 1.5e-07 31.2 0.0 3.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE25463.1 - 2.1e-07 31.5 0.0 6.8e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE25463.1 - 4.4e-07 30.2 0.0 0.011 16.2 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EPE25463.1 - 1.4e-05 24.7 0.1 0.00025 20.6 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE25463.1 - 4.3e-05 23.8 0.0 0.0046 17.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EPE25463.1 - 0.0022 17.0 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family DUF2961 PF11175.3 EPE25465.1 - 0.0036 16.6 0.2 0.0051 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Aminotran_1_2 PF00155.16 EPE25466.1 - 7.9e-42 143.4 0.0 1.1e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PAS_9 PF13426.1 EPE25467.1 - 8.5e-17 61.4 0.0 4.6e-15 55.8 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EPE25467.1 - 0.0025 17.5 0.0 0.009 15.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold RTA1 PF04479.8 EPE25468.1 - 1.3e-38 132.7 7.6 1.7e-38 132.3 5.3 1.1 1 0 0 1 1 1 1 RTA1 like protein ATP_bind_2 PF03668.10 EPE25469.1 - 0.00068 18.8 0.0 0.023 13.7 0.0 2.1 2 0 0 2 2 2 2 P-loop ATPase protein family DSPc PF00782.15 EPE25469.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain SAPS PF04499.10 EPE25469.1 - 0.13 10.8 4.3 0.17 10.4 3.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ADH_zinc_N PF00107.21 EPE25470.1 - 1.9e-15 56.5 0.1 3.3e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE25470.1 - 8.6e-13 49.2 0.0 1.6e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE25470.1 - 1.3e-05 24.9 0.0 0.0057 16.4 0.0 2.9 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 EPE25470.1 - 0.0063 16.8 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_4 PF01565.18 EPE25471.1 - 3.9e-32 110.6 5.0 7.5e-32 109.7 3.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE25471.1 - 3.9e-08 33.0 0.1 4.5e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EPE25471.1 - 0.016 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding zf-Nse PF11789.3 EPE25472.1 - 1e-16 60.1 0.0 2.4e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Cwf_Cwc_15 PF04889.7 EPE25472.1 - 0.0026 17.5 3.6 0.0026 17.5 2.5 2.6 2 1 1 3 3 3 1 Cwf15/Cwc15 cell cycle control protein zf-RING_UBOX PF13445.1 EPE25472.1 - 0.019 14.6 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Fungal_trans_2 PF11951.3 EPE25473.1 - 5.2e-08 31.8 0.2 7.5e-08 31.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EPE25474.1 - 1.6e-33 115.9 33.8 4.6e-19 68.3 8.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPE25474.1 - 1.6e-16 59.9 43.6 4.5e-11 42.0 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3425 PF11905.3 EPE25475.1 - 1.1e-33 116.0 1.5 2.1e-33 115.1 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.20 EPE25476.1 - 1.1e-14 54.6 0.1 1.5e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE25476.1 - 1.3e-06 28.3 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE25476.1 - 0.0003 20.4 0.3 0.00054 19.6 0.2 1.4 1 1 0 1 1 1 1 KR domain DIL PF01843.14 EPE25476.1 - 0.088 12.6 0.0 0.69 9.8 0.0 2.1 2 0 0 2 2 2 0 DIL domain Nit_Regul_Hom PF10126.4 EPE25476.1 - 0.15 11.8 0.2 1.1 9.0 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII VSP PF03302.8 EPE25479.1 - 0.017 13.7 1.4 0.021 13.4 1.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein CD99L2 PF12301.3 EPE25479.1 - 0.088 12.4 2.0 0.11 12.2 0.6 1.6 1 1 1 2 2 2 0 CD99 antigen like protein 2 DUF4027 PF13219.1 EPE25479.1 - 0.77 9.2 3.4 0.8 9.1 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4027) NUC153 PF08159.7 EPE25480.1 - 3.6e-14 52.0 2.7 8.3e-14 50.8 1.9 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EPE25480.1 - 2.8e-06 26.9 0.0 0.034 14.0 0.0 5.0 6 0 0 6 6 6 1 WD domain, G-beta repeat Med13_C PF06333.7 EPE25481.1 - 5.3e-85 285.5 0.0 1.1e-84 284.4 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EPE25481.1 - 2e-36 125.5 0.1 3.4e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal PNP_UDP_1 PF01048.15 EPE25481.1 - 1.5e-30 105.9 0.0 2.5e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily TauD PF02668.11 EPE25482.1 - 5.8e-44 150.7 0.1 7.1e-44 150.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Clathrin PF00637.15 EPE25483.1 - 5.2e-18 65.0 1.7 5.2e-18 65.0 1.2 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.3 EPE25483.1 - 1.8e-13 50.1 1.6 2.5e-13 49.6 0.2 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal TPR_14 PF13428.1 EPE25483.1 - 0.0014 19.0 0.2 3.7 8.4 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat zf-RING_5 PF14634.1 EPE25483.1 - 0.0017 18.0 4.9 0.0033 17.1 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.1 EPE25483.1 - 0.0021 17.6 0.9 0.0071 15.9 0.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EPE25483.1 - 0.0036 17.0 2.2 0.017 15.0 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_2 PF13639.1 EPE25483.1 - 0.0041 16.9 4.2 0.0095 15.7 2.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.1 EPE25483.1 - 0.013 15.5 1.2 0.013 15.5 0.8 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-Apc11 PF12861.2 EPE25483.1 - 0.016 15.0 1.8 0.038 13.8 1.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EPE25483.1 - 0.038 14.0 3.6 0.087 12.8 2.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 EPE25483.1 - 0.33 10.9 8.0 1.2 9.1 0.1 3.8 4 1 0 4 4 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 EPE25483.1 - 0.62 9.7 3.9 1.3 8.7 2.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.1 EPE25483.1 - 1.3 8.9 9.3 0.14 12.0 0.6 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.1 EPE25483.1 - 1.5 8.7 3.9 2.9 7.8 2.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EPE25483.1 - 1.7 8.8 5.8 4.9 7.3 4.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger TPR_1 PF00515.23 EPE25483.1 - 2.9 7.6 5.4 3.8 7.2 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPE25483.1 - 3.6 8.0 9.2 19 5.6 0.6 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Miro PF08477.8 EPE25485.1 - 3.1e-35 121.2 0.0 1.9e-18 67.1 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EPE25485.1 - 3.8e-33 113.0 0.0 8.4e-33 112.0 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EPE25485.1 - 1.2e-30 104.5 0.3 2.1e-30 103.7 0.2 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EPE25485.1 - 1.5e-25 89.4 0.0 1.8e-16 59.9 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EPE25485.1 - 1.4e-08 34.6 0.0 0.00064 19.6 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPE25485.1 - 4.5e-07 29.8 0.1 0.083 12.6 0.0 3.3 2 1 1 3 3 3 2 Dynamin family EF-hand_7 PF13499.1 EPE25485.1 - 5.3e-07 29.6 1.0 0.01 15.9 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair AAA_16 PF13191.1 EPE25485.1 - 6.2e-06 26.3 0.1 0.062 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_1 PF00036.27 EPE25485.1 - 2.4e-05 23.2 4.0 0.097 12.0 0.1 2.7 2 0 0 2 2 2 2 EF hand AAA_29 PF13555.1 EPE25485.1 - 4.8e-05 22.8 0.0 0.1 12.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EPE25485.1 - 0.00016 21.1 0.0 0.8 9.1 0.0 3.2 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.1 EPE25485.1 - 0.00028 20.5 4.6 0.16 11.9 0.5 2.7 2 0 0 2 2 2 2 EF-hand domain AAA_28 PF13521.1 EPE25485.1 - 0.00049 20.0 0.0 0.23 11.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EPE25485.1 - 0.00094 19.3 0.0 0.38 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPE25485.1 - 0.0078 15.9 0.0 0.39 10.4 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EPE25485.1 - 0.0097 16.0 0.0 0.43 10.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase EF-hand_8 PF13833.1 EPE25485.1 - 0.014 14.9 3.4 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair ABC_tran PF00005.22 EPE25485.1 - 0.017 15.4 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 EPE25485.1 - 0.028 14.0 0.0 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EPE25485.1 - 0.029 14.2 0.0 12 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EPE25485.1 - 0.044 12.8 0.0 4.4 6.3 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.1 EPE25485.1 - 0.045 13.1 0.0 5.6 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EPE25485.1 - 0.05 13.3 0.0 3 7.4 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 EPE25485.1 - 0.054 12.6 0.0 0.47 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF463 PF04317.7 EPE25485.1 - 0.089 11.3 0.0 0.36 9.3 0.0 1.8 2 0 0 2 2 2 0 YcjX-like family, DUF463 FtsK_SpoIIIE PF01580.13 EPE25485.1 - 0.11 11.9 0.0 9.4 5.6 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family EF-hand_5 PF13202.1 EPE25485.1 - 0.14 11.5 6.8 0.77 9.2 2.0 2.7 2 0 0 2 2 2 0 EF hand WD40 PF00400.27 EPE25486.1 - 1.8e-20 71.9 16.0 4.4e-06 26.3 0.4 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EPE25486.1 - 0.00038 20.2 0.0 0.0035 17.0 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EPE25486.1 - 0.0043 14.9 0.0 0.0079 14.0 0.0 1.4 1 1 0 1 1 1 1 IKI3 family Cytochrom_D1 PF02239.11 EPE25486.1 - 0.016 13.5 0.0 0.029 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Band_7 PF01145.20 EPE25488.1 - 4.9e-14 52.6 0.0 4.9e-14 52.6 0.0 2.9 2 2 0 2 2 2 1 SPFH domain / Band 7 family PhyH PF05721.8 EPE25489.1 - 1.4e-05 25.2 0.0 9.9e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2433 PF10360.4 EPE25490.1 - 2e-54 183.4 0.0 3e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EPE25490.1 - 0.0062 16.3 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2360 PF10152.4 EPE25490.1 - 0.032 14.5 6.2 1 9.6 4.1 2.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos PF00149.23 EPE25490.1 - 0.1 11.9 0.0 0.37 10.1 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase TFIIA PF03153.8 EPE25490.1 - 4.9 6.9 9.2 8.4 6.1 6.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ubie_methyltran PF01209.13 EPE25491.1 - 5.3e-80 267.8 0.0 6.8e-80 267.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EPE25491.1 - 3e-15 56.1 0.0 4.2e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE25491.1 - 8.3e-14 51.8 0.0 2e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE25491.1 - 6.6e-11 42.5 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE25491.1 - 4.8e-10 39.3 0.0 1.5e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE25491.1 - 3e-09 37.1 0.0 5.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE25491.1 - 9.3e-08 32.6 0.0 1.6e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE25491.1 - 0.00027 20.9 0.0 0.00081 19.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Bac_luciferase PF00296.15 EPE25492.1 - 1.2e-62 211.7 0.0 1.4e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase His_Phos_1 PF00300.17 EPE25493.1 - 1.4e-14 54.4 0.3 3.7e-14 53.1 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Gly_transf_sug PF04488.10 EPE25495.1 - 1.4e-09 38.2 0.0 3.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EPE25495.1 - 0.0071 14.8 0.1 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain zf-CCCH PF00642.19 EPE25496.1 - 2.9e-06 26.7 2.5 6.2e-06 25.7 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cpn60_TCP1 PF00118.19 EPE25497.1 - 9.4e-148 492.8 6.1 1.1e-147 492.6 4.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 EPE25497.1 - 0.12 12.3 2.5 20 5.1 0.0 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Pkinase PF00069.20 EPE25498.1 - 6.4e-71 238.5 0.0 9.2e-71 238.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25498.1 - 1.7e-45 155.1 0.0 2.6e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EPE25498.1 - 1.3e-20 73.5 0.1 5.8e-20 71.4 0.1 2.3 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EPE25498.1 - 5.1e-07 28.9 0.0 8e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPE25498.1 - 0.071 12.8 1.6 0.19 11.4 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 EPE25498.1 - 0.15 11.2 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.9 EPE25498.1 - 0.22 10.5 0.2 0.69 8.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family KH_1 PF00013.24 EPE25499.1 - 2.7e-98 321.5 26.0 1e-13 50.6 1.0 12.0 11 2 0 11 11 11 9 KH domain KH_3 PF13014.1 EPE25499.1 - 4.2e-68 224.0 29.2 2.4e-11 43.0 0.4 12.1 12 0 0 12 12 12 9 KH domain KH_2 PF07650.12 EPE25499.1 - 1.2e-13 50.3 21.6 0.0027 17.2 0.1 8.3 7 1 0 8 8 8 5 KH domain SLS PF14611.1 EPE25499.1 - 1.8e-10 40.5 11.9 0.0022 17.4 0.5 8.2 5 3 3 9 9 9 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 EPE25499.1 - 8e-05 22.2 13.8 0.18 11.4 0.0 7.6 9 0 0 9 9 9 1 KH domain KH_5 PF13184.1 EPE25499.1 - 0.024 14.4 19.2 0.46 10.3 0.0 7.3 8 1 1 9 9 9 0 NusA-like KH domain ExbD PF02472.11 EPE25499.1 - 0.78 9.7 7.4 2.8 7.9 0.0 3.8 3 1 0 4 4 4 0 Biopolymer transport protein ExbD/TolR NUDIX PF00293.23 EPE25500.1 - 1.9e-12 46.9 0.3 3.1e-12 46.2 0.2 1.3 1 1 0 1 1 1 1 NUDIX domain Chromo_shadow PF01393.14 EPE25501.1 - 4e-12 45.7 0.1 1.1e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.19 EPE25501.1 - 9.2e-12 44.4 1.4 4.4e-11 42.2 0.3 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3022 PF11226.3 EPE25501.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) DUF2457 PF10446.4 EPE25501.1 - 4.9 5.7 12.4 9 4.9 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAD_binding_3 PF01494.14 EPE25502.1 - 2.3e-22 79.5 0.1 4.3e-22 78.6 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EPE25502.1 - 1.1e-07 31.3 0.6 0.00042 19.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EPE25502.1 - 2.3e-06 26.7 0.0 0.02 13.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE25502.1 - 8e-06 25.0 0.1 0.0037 16.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPE25502.1 - 0.00099 19.0 0.1 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPE25502.1 - 0.0029 17.9 0.7 0.052 13.9 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE25502.1 - 0.0054 16.6 0.1 0.022 14.6 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EPE25503.1 - 4.7e-31 107.9 0.6 6.8e-31 107.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE25503.1 - 3.1e-27 95.9 1.1 4.3e-27 95.4 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE25503.1 - 6e-13 48.8 0.1 8.6e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE25503.1 - 0.00012 21.5 0.1 0.00023 20.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 EPE25503.1 - 0.00047 19.7 0.9 0.004 16.8 0.2 2.6 2 1 0 2 2 2 1 PA domain Polysacc_synt_2 PF02719.10 EPE25503.1 - 0.0027 16.6 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.10 EPE25503.1 - 0.053 13.1 0.9 0.46 10.0 0.8 2.5 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein CbiA PF01656.18 EPE25503.1 - 0.063 12.6 0.1 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Acetyltransf_1 PF00583.19 EPE25504.1 - 2.3e-09 37.1 1.0 6.9e-09 35.6 0.7 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE25504.1 - 2.8e-09 37.0 0.1 1.3e-07 31.6 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE25504.1 - 7.5e-06 26.0 0.1 0.00022 21.3 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE25504.1 - 0.00035 20.4 0.0 0.02 14.7 0.0 2.6 2 2 0 2 2 2 1 Acetyltransferase (GNAT) domain ARID PF01388.16 EPE25505.1 - 1.1e-19 70.0 0.0 2.9e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain HRXXH PF13933.1 EPE25506.1 - 0.00057 19.3 5.0 0.0018 17.7 3.5 1.7 1 1 0 1 1 1 1 Putative peptidase family SelR PF01641.13 EPE25508.1 - 8.3e-50 167.6 0.1 1.1e-49 167.2 0.1 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 EPE25508.1 - 0.015 15.0 0.9 3 7.7 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 EPE25508.1 - 0.018 14.7 0.2 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) GFA PF04828.9 EPE25508.1 - 0.019 14.9 0.5 1.3 8.9 0.0 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.7 EPE25508.1 - 0.073 12.3 1.5 0.63 9.4 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding ArfGap PF01412.13 EPE25509.1 - 5.6e-41 138.9 0.3 8.6e-41 138.3 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF4349 PF14257.1 EPE25510.1 - 0.032 13.4 0.1 0.038 13.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF500 PF04366.7 EPE25511.1 - 5.8e-44 148.5 0.2 9.3e-44 147.8 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EPE25511.1 - 3e-13 48.9 0.1 9.6e-13 47.3 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EPE25511.1 - 3.1e-13 49.0 0.0 9.1e-13 47.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EPE25511.1 - 2.8e-12 45.9 0.1 7.2e-12 44.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Wbp11 PF09429.5 EPE25512.1 - 4.3e-22 77.8 12.5 4.3e-22 77.8 8.6 2.2 2 0 0 2 2 2 1 WW domain binding protein 11 DUF3450 PF11932.3 EPE25512.1 - 0.17 11.1 2.4 0.32 10.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FSH1 PF03959.8 EPE25513.1 - 4.4e-28 98.1 0.0 5.6e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EPE25513.1 - 0.00029 20.5 0.0 0.00063 19.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE25513.1 - 0.00068 19.1 0.0 0.0067 15.9 0.0 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EPE25513.1 - 0.0081 16.0 0.0 0.74 9.6 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE25513.1 - 0.13 11.8 0.0 1.5 8.3 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold ADH_zinc_N PF00107.21 EPE25514.1 - 1.8e-21 76.0 0.0 2.5e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE25514.1 - 1e-15 57.4 0.9 1.9e-15 56.5 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 EPE25514.1 - 0.0059 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EPE25514.1 - 0.031 15.1 0.0 0.054 14.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.13 EPE25514.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF2183 PF09949.4 EPE25515.1 - 4.2e-17 61.9 0.1 7.5e-17 61.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF2435 PF10363.4 EPE25516.1 - 8.1e-20 70.5 0.9 7.9e-18 64.1 0.1 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EPE25516.1 - 6.1e-10 38.3 0.1 1.9e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DUF4042 PF13251.1 EPE25516.1 - 0.064 12.7 1.4 1.6 8.1 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4042) WAC_Acf1_DNA_bd PF10537.4 EPE25518.1 - 0.002 18.2 0.6 0.0059 16.7 0.1 2.0 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal zf-MIZ PF02891.15 EPE25518.1 - 6.7 6.3 9.7 4.9 6.7 0.2 3.4 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger TPPII_N PF12583.3 EPE25519.1 - 0.073 13.2 0.1 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal ApbA PF02558.11 EPE25520.1 - 1.1e-24 86.5 0.0 1.6e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPE25520.1 - 1.7e-23 82.9 0.0 2.5e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF4271 PF14093.1 EPE25521.1 - 0.0086 15.7 3.6 0.015 15.0 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) FliJ PF02050.11 EPE25521.1 - 0.025 14.6 2.0 0.028 14.4 0.2 1.9 2 0 0 2 2 2 0 Flagellar FliJ protein Agglutinin PF07468.6 EPE25521.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Agglutinin CMV_1a PF12467.3 EPE25523.1 - 0.012 16.0 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family BRI3BP PF14965.1 EPE25523.1 - 0.039 13.3 4.2 0.058 12.7 2.9 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 YfhD PF14151.1 EPE25523.1 - 0.11 12.6 0.6 0.26 11.4 0.4 1.6 1 0 0 1 1 1 0 YfhD-like protein DUF1700 PF08006.6 EPE25523.1 - 0.23 10.7 8.6 0.34 10.1 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Robl_LC7 PF03259.12 EPE25526.1 - 1.5e-11 43.6 0.1 1e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.3 EPE25527.1 - 1.8e-24 85.6 0.6 1.1e-23 83.1 0.0 2.3 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Pyrid_oxidase_2 PF13883.1 EPE25528.1 - 9e-47 158.9 0.0 1.1e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_S30 PF04758.9 EPE25529.1 - 2.8e-29 100.6 7.2 3.3e-29 100.3 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Rpr2 PF04032.11 EPE25530.1 - 8.8e-16 57.5 1.7 7.8e-15 54.5 1.1 2.0 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DEAD PF00270.24 EPE25531.1 - 2.5e-36 124.7 0.1 4.2e-36 123.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE25531.1 - 1.7e-23 82.2 0.0 2.4e-22 78.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE25531.1 - 1.3e-06 28.4 0.0 2.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4572 PF15139.1 EPE25531.1 - 0.12 12.1 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) DASH_Dam1 PF08653.5 EPE25532.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 DUF1691 PF07950.6 EPE25533.1 - 0.078 12.9 0.0 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) ECH PF00378.15 EPE25534.1 - 5.2e-29 101.0 0.0 7.2e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Glyoxalase_3 PF13468.1 EPE25535.1 - 3.8e-05 23.6 0.0 4.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EPE25535.1 - 5.1e-05 23.2 0.0 0.00015 21.7 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF302 PF03625.9 EPE25536.1 - 1.6e-08 34.0 0.0 4.1e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF302 ADH_zinc_N PF00107.21 EPE25537.1 - 2.8e-17 62.4 0.0 4.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE25537.1 - 3e-10 41.0 0.0 6.1e-10 40.0 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glyco_hydro_7 PF00840.15 EPE25538.1 - 1.3e-202 672.9 18.8 1.5e-202 672.7 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 BUD22 PF09073.5 EPE25539.1 - 5.6e-79 266.2 20.2 8.5e-79 265.6 14.0 1.3 1 0 0 1 1 1 1 BUD22 DUF605 PF04652.11 EPE25539.1 - 0.0044 16.4 7.9 0.0059 16.0 5.5 1.3 1 0 0 1 1 1 1 Vta1 like WSC PF01822.14 EPE25540.1 - 7.4e-14 51.4 5.1 1.6e-13 50.3 3.5 1.6 1 0 0 1 1 1 1 WSC domain VIT1 PF01988.14 EPE25540.1 - 0.096 12.1 0.2 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 VIT family GATA PF00320.22 EPE25543.1 - 9.8e-17 60.0 2.1 2.1e-16 58.9 1.5 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EPE25543.1 - 5.1e-14 51.5 4.6 9.3e-14 50.7 3.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.6 EPE25543.1 - 6.4 7.4 19.0 0.096 13.2 5.5 3.9 3 1 0 3 3 3 0 Nitrogen regulatory protein AreA N terminus POP1 PF06978.6 EPE25544.1 - 1.2e-63 214.2 10.0 2.1e-63 213.4 6.9 1.4 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EPE25544.1 - 6.1e-32 109.3 0.3 1.5e-31 108.0 0.2 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain Adeno_terminal PF02459.10 EPE25544.1 - 0.049 11.8 4.0 0.072 11.2 2.8 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein HgmA PF04209.8 EPE25545.1 - 7e-156 518.8 0.1 8e-156 518.6 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase NAD_binding_10 PF13460.1 EPE25546.1 - 1.1e-10 41.8 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 EPE25546.1 - 1.1e-05 24.0 0.0 4e-05 22.2 0.0 1.8 1 1 0 2 2 2 1 HIM1 Epimerase PF01370.16 EPE25546.1 - 9.1e-05 21.9 0.0 0.00085 18.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EPE25546.1 - 0.0013 19.0 0.0 0.0033 17.7 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EPE25546.1 - 0.0024 16.8 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EPE25546.1 - 0.0033 16.7 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family HET PF06985.6 EPE25547.1 - 7.7e-23 81.1 0.0 1.3e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_1 PF00667.15 EPE25548.1 - 1.1e-61 208.0 0.0 1.9e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPE25548.1 - 3e-11 43.8 0.0 8.6e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EPE25548.1 - 7.9e-06 25.8 0.0 2.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EPE25548.1 - 8.8e-05 22.4 0.1 0.00025 20.9 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Glyco_hydro_61 PF03443.9 EPE25549.1 - 6.6e-54 183.0 0.0 7.8e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RNA_pol_Rpb5_N PF03871.9 EPE25550.1 - 0.069 13.5 0.9 0.18 12.2 0.4 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain FYVE_2 PF02318.11 EPE25550.1 - 0.65 9.9 4.2 1.7 8.5 0.2 3.0 3 0 0 3 3 3 0 FYVE-type zinc finger Chal_sti_synt_C PF02797.10 EPE25552.1 - 8.6e-22 77.6 0.0 1.7e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 EPE25552.1 - 3.2e-20 72.3 0.1 5e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.7 EPE25552.1 - 3.2e-06 26.4 0.0 4.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 EPE25552.1 - 4e-06 26.7 0.0 0.00022 21.1 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EPE25552.1 - 0.0027 17.3 0.0 0.0073 15.9 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF4142 PF13628.1 EPE25553.1 - 0.032 14.2 1.7 0.048 13.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) UPF0184 PF03670.8 EPE25553.1 - 3.8 7.7 8.8 11 6.2 0.5 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) TRAUB PF08164.7 EPE25554.1 - 1.2e-30 105.4 0.0 7e-30 102.9 0.0 2.5 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EPE25554.1 - 8.1e-28 97.1 3.4 8.1e-28 97.1 2.3 2.9 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor Protamine_P2 PF00841.14 EPE25554.1 - 0.39 11.2 2.4 1.3 9.6 1.7 1.8 1 0 0 1 1 1 0 Sperm histone P2 ParA PF10609.4 EPE25555.1 - 9.8e-35 118.3 1.6 4.4e-34 116.2 0.5 2.3 3 0 0 3 3 3 1 ParA/MinD ATPase like CbiA PF01656.18 EPE25555.1 - 4.5e-16 58.8 0.1 6.6e-16 58.3 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EPE25555.1 - 3.2e-08 33.6 0.1 3.4e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EPE25555.1 - 1.6e-05 24.1 0.0 2.3e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 EPE25555.1 - 0.001 18.5 0.2 0.0027 17.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EPE25555.1 - 0.0024 16.9 0.9 0.046 12.7 0.2 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase Rhomboid PF01694.17 EPE25555.1 - 0.0096 15.9 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 1 Rhomboid family AAA_19 PF13245.1 EPE25555.1 - 0.028 14.1 0.7 6 6.6 0.0 2.7 3 0 0 3 3 3 0 Part of AAA domain Fer4_NifH PF00142.13 EPE25555.1 - 0.028 13.5 0.0 0.48 9.5 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DegS PF05384.6 EPE25556.1 - 0.0013 17.9 4.7 0.0016 17.6 0.7 2.4 2 0 0 2 2 2 1 Sensor protein DegS HD_assoc PF13286.1 EPE25556.1 - 0.0036 17.5 1.5 0.33 11.2 0.1 3.0 3 0 0 3 3 3 1 Phosphohydrolase-associated domain Tht1 PF04163.7 EPE25556.1 - 0.077 11.3 12.5 0.034 12.5 5.9 2.3 2 1 0 2 2 2 0 Tht1-like nuclear fusion protein HEAT_EZ PF13513.1 EPE25559.1 - 2.8e-19 69.0 21.9 5.7e-05 23.4 0.1 11.3 10 3 5 15 15 13 5 HEAT-like repeat HEAT PF02985.17 EPE25559.1 - 7.9e-19 65.9 7.8 0.00041 20.1 0.0 11.0 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 EPE25559.1 - 5.5e-17 61.8 11.4 0.0049 17.1 0.0 7.8 4 3 5 9 9 9 7 HEAT repeats Vac14_Fab1_bd PF12755.2 EPE25559.1 - 6.2e-09 36.1 0.0 0.11 12.8 0.0 6.9 6 3 2 8 8 7 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EPE25559.1 - 5.1e-07 28.3 0.0 0.0016 16.8 0.0 3.6 4 0 0 4 4 4 1 Adaptin N terminal region IBN_N PF03810.14 EPE25559.1 - 1.8e-06 27.7 2.1 5e-06 26.3 0.1 2.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EPE25559.1 - 3.8e-06 26.4 1.1 0.084 12.2 0.0 5.2 4 1 1 6 6 6 1 CLASP N terminal Arm PF00514.18 EPE25559.1 - 1.2e-05 24.9 12.8 0.034 13.9 0.0 8.2 10 0 0 10 10 9 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EPE25559.1 - 5.4e-05 23.1 1.0 6 6.6 0.4 5.3 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EPE25559.1 - 0.0005 20.0 0.1 0.0081 16.0 0.0 3.0 3 1 0 3 3 3 1 Parkin co-regulated protein MMS19_C PF12460.3 EPE25559.1 - 0.0035 16.1 5.8 0.043 12.5 0.0 4.2 5 0 0 5 5 5 1 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.11 EPE25559.1 - 3.3 8.4 8.3 36 5.2 0.0 5.1 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Acetyltransf_1 PF00583.19 EPE25560.1 - 5.1e-06 26.4 0.0 8.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE25560.1 - 5.6e-05 23.2 0.0 8.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE25560.1 - 0.015 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cas_GSU0053 PF09617.5 EPE25560.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) DUF4339 PF14237.1 EPE25560.1 - 0.029 13.9 2.7 4.4 6.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4339) MOZ_SAS PF01853.13 EPE25560.1 - 0.13 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Aldo_ket_red PF00248.16 EPE25562.1 - 1.6e-44 151.8 0.0 2.2e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family eRF1_1 PF03463.10 EPE25563.1 - 1.7e-46 157.0 0.1 3e-46 156.2 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EPE25563.1 - 6.1e-23 81.6 0.0 8.7e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EPE25563.1 - 1.5e-20 73.5 0.0 3e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 PTPA PF03095.10 EPE25565.1 - 4.1e-109 364.3 0.0 4.9e-109 364.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein TFIIA PF03153.8 EPE25566.1 - 1.4 8.7 8.8 1.6 8.5 6.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fib_alpha PF08702.5 EPE25567.1 - 0.00087 19.4 6.7 0.00087 19.4 4.7 9.0 2 1 7 10 10 10 4 Fibrinogen alpha/beta chain family Filament PF00038.16 EPE25567.1 - 0.15 11.5 147.0 0.18 11.2 27.9 5.6 2 2 2 5 5 5 0 Intermediate filament protein TCO89 PF10452.4 EPE25569.1 - 1.7 7.4 37.5 5.2 5.8 0.0 3.2 2 1 0 2 2 2 0 TORC1 subunit TCO89 Med5 PF08689.5 EPE25569.1 - 8.8 3.8 6.7 13 3.3 4.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit Med5 PEPCK_ATP PF01293.15 EPE25570.1 - 6.4e-213 707.4 0.0 8.1e-213 707.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EPE25570.1 - 0.0061 16.8 0.1 1.8 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EPE25570.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Mid2 PF04478.7 EPE25571.1 - 0.019 14.4 0.6 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor UQ_con PF00179.21 EPE25572.1 - 5.7e-35 119.7 0.1 7.3e-35 119.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pantoate_transf PF02548.10 EPE25573.1 - 3.8e-102 340.8 0.2 4.5e-102 340.6 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EPE25573.1 - 8.9e-08 31.6 0.6 1.7e-07 30.7 0.4 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase APG12 PF04110.8 EPE25574.1 - 4.2e-27 94.1 0.0 4.9e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EPE25574.1 - 3.9e-05 23.5 0.0 4.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Peptidase_M24 PF00557.19 EPE25575.1 - 2.4e-50 170.9 0.0 3.7e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EPE25575.1 - 1.2e-36 125.1 0.0 2.2e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.5 EPE25576.1 - 5.2e-43 145.7 0.7 3.9e-42 142.9 0.0 2.6 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 EPE25576.1 - 1.5e-23 82.1 1.1 4e-23 80.8 0.8 1.8 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 EPE25576.1 - 0.0014 18.4 0.0 0.0046 16.7 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain zf-C2H2_2 PF12756.2 EPE25576.1 - 0.025 14.6 1.6 0.062 13.4 1.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) BRCT PF00533.21 EPE25576.1 - 0.04 14.0 0.3 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Abhydrolase_6 PF12697.2 EPE25578.1 - 1.3e-16 61.2 0.0 1.8e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE25578.1 - 9.8e-10 38.3 0.0 1.2e-09 38.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EPE25578.1 - 0.0006 19.4 0.0 0.00095 18.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EPE25578.1 - 0.0062 15.3 0.0 0.012 14.4 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EPE25578.1 - 0.0086 14.9 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EPE25578.1 - 0.014 14.9 0.0 0.056 12.9 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE25578.1 - 0.027 13.7 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.8 EPE25578.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein UCH_1 PF13423.1 EPE25579.1 - 1.2e-53 182.4 0.0 1.8e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EPE25579.1 - 5.7e-26 91.7 0.0 1.1e-25 90.8 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EPE25579.1 - 0.00068 18.8 0.0 0.004 16.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase eIF2A PF08662.6 EPE25579.1 - 0.05 13.3 0.1 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A adh_short PF00106.20 EPE25580.1 - 9.2e-17 61.4 0.0 1.4e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE25580.1 - 6.6e-10 38.9 0.1 9.7e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 EPE25581.1 - 0.00086 18.2 3.7 0.0019 17.0 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE25581.1 - 0.00092 19.0 9.4 0.0021 17.9 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phtf-FEM1B_bdg PF12129.3 EPE25581.1 - 0.16 11.2 0.1 0.4 10.0 0.0 1.6 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor MFS_1 PF07690.11 EPE25582.1 - 3.4e-45 154.2 47.4 3.4e-45 154.2 32.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE25582.1 - 5.7e-12 44.6 19.4 8.7e-12 44.0 13.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.20 EPE25583.1 - 6.5e-32 110.7 0.0 4.7e-15 55.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25583.1 - 9e-15 54.4 0.0 3.6e-07 29.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase zf-RING_UBOX PF13445.1 EPE25583.1 - 0.075 12.7 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DUF605 PF04652.11 EPE25583.1 - 0.44 9.9 15.3 0.65 9.3 10.6 1.2 1 0 0 1 1 1 0 Vta1 like PAP1 PF08601.5 EPE25584.1 - 7.5e-57 193.5 44.4 8.6e-49 167.0 7.0 4.5 2 2 2 4 4 4 3 Transcription factor PAP1 bZIP_1 PF00170.16 EPE25584.1 - 1.9e-08 34.0 9.9 4.1e-08 33.0 6.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPE25584.1 - 0.0067 16.2 10.7 0.021 14.6 7.4 1.8 1 1 0 1 1 1 1 Basic region leucine zipper GAS PF13851.1 EPE25584.1 - 0.0096 15.1 5.8 0.016 14.4 4.0 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Adeno_PIX PF03955.9 EPE25584.1 - 0.033 14.7 1.2 0.033 14.7 0.8 2.5 3 0 0 3 3 1 0 Adenovirus hexon-associated protein (IX) IncA PF04156.9 EPE25584.1 - 0.044 13.3 3.1 0.09 12.3 2.1 1.4 1 0 0 1 1 1 0 IncA protein bZIP_Maf PF03131.12 EPE25584.1 - 0.054 13.8 8.5 0.11 12.8 5.9 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor CENP-H PF05837.7 EPE25584.1 - 0.18 11.9 4.3 0.47 10.6 3.0 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) NAM-associated PF14303.1 EPE25584.1 - 2.1 8.6 18.4 0.19 12.0 9.2 1.8 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Bap31 PF05529.7 EPE25584.1 - 7.3 6.0 6.1 14 5.0 4.2 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Sigma70_ner PF04546.8 EPE25584.1 - 7.7 6.0 12.5 2.9 7.4 6.4 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region XhlA PF10779.4 EPE25584.1 - 8.8 6.3 5.8 2.9 7.8 1.8 1.8 2 0 0 2 2 2 0 Haemolysin XhlA BSD PF03909.12 EPE25585.1 - 3.7e-14 52.1 1.0 8.3e-14 51.0 0.7 1.6 1 0 0 1 1 1 1 BSD domain Suf PF05843.9 EPE25585.1 - 0.17 11.5 5.0 0.027 14.2 0.8 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) WGG PF10273.4 EPE25586.1 - 2.2e-31 107.7 0.7 3.4e-31 107.1 0.5 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 NPDC1 PF06809.6 EPE25586.1 - 0.061 12.1 0.6 0.078 11.7 0.4 1.1 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) RRP7 PF12923.2 EPE25586.1 - 2.3 8.2 6.5 2.9 7.9 0.1 2.3 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Abhydrolase_3 PF07859.8 EPE25587.1 - 1.7e-41 142.1 0.0 3.1e-32 111.8 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EPE25587.1 - 5.2e-14 51.6 0.0 2.5e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EPE25587.1 - 8.6e-06 24.7 0.9 0.00023 20.0 0.6 2.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EPE25587.1 - 0.00029 20.6 0.0 0.00059 19.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIN37 PF15306.1 EPE25587.1 - 1.7 8.6 8.8 0.2 11.6 2.5 2.1 2 0 0 2 2 2 0 LIN37 Cellulase PF00150.13 EPE25588.1 - 1.1e-10 41.1 0.7 1.1e-10 41.1 0.5 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF3357 PF11837.3 EPE25588.1 - 0.00028 20.6 0.0 0.00028 20.6 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3357) ODV-E18 PF10717.4 EPE25588.1 - 0.077 12.4 0.3 0.19 11.2 0.2 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF1510 PF07423.6 EPE25588.1 - 0.17 11.2 0.1 0.17 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Protocadherin PF08374.6 EPE25588.1 - 0.46 10.0 0.0 0.46 10.0 0.0 2.8 2 1 1 3 3 3 0 Protocadherin Transket_pyr PF02779.19 EPE25589.1 - 1.7e-41 141.6 0.0 2.3e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EPE25589.1 - 1.3e-29 102.6 0.0 2.8e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain F-actin_cap_A PF01267.12 EPE25590.1 - 2.8e-95 318.4 0.0 3.2e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF2648 PF10855.3 EPE25590.1 - 0.23 10.9 0.6 0.65 9.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) Cyt-b5 PF00173.23 EPE25591.1 - 5.1e-23 80.6 0.2 6.6e-23 80.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-RING_2 PF13639.1 EPE25592.1 - 2e-08 33.9 2.2 3.1e-08 33.3 1.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPE25592.1 - 3e-06 27.2 0.3 5.6e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPE25592.1 - 4e-05 23.3 0.8 6.7e-05 22.6 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EPE25592.1 - 0.00034 20.5 2.1 0.00053 19.9 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE25592.1 - 0.0019 17.8 0.5 0.0038 16.8 0.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE25592.1 - 0.012 15.2 1.7 0.021 14.4 1.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EPE25592.1 - 0.054 12.6 2.5 3.8 6.6 0.1 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EPE25592.1 - 0.06 13.0 0.7 0.12 12.1 0.4 1.6 1 1 0 1 1 1 0 RING-type zinc-finger Ribosomal_60s PF00428.14 EPE25592.1 - 5 7.5 5.5 9.2 6.7 3.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein MFS_1 PF07690.11 EPE25593.1 - 2e-51 174.7 33.8 8.2e-50 169.4 24.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4245 PF14030.1 EPE25593.1 - 0.11 12.1 3.7 0.67 9.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4245) Ribosomal_S5_C PF03719.10 EPE25594.1 - 5.9e-19 67.1 0.3 1.5e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EPE25594.1 - 8.2e-10 38.2 0.0 1.7e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.5 EPE25595.1 - 4.5e-28 96.7 0.3 5.2e-28 96.5 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Baculo_gp64 PF03273.8 EPE25595.1 - 0.052 11.7 0.0 0.059 11.5 0.0 1.0 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family FBPase_2 PF06874.6 EPE25595.1 - 0.072 11.1 0.0 0.074 11.0 0.0 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Vac_Fusion PF02346.11 EPE25595.1 - 0.11 11.9 0.1 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DUF2317 PF10079.4 EPE25595.1 - 0.13 10.8 0.1 0.16 10.5 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Fungal_trans PF04082.13 EPE25596.1 - 3.1e-09 36.1 0.0 4.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE25596.1 - 1.1e-08 34.7 7.3 2e-08 33.9 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 EPE25597.1 - 1.1e-26 93.2 25.7 1.8e-26 92.6 17.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EPE25597.1 - 1.1e-24 87.2 0.1 1.7e-24 86.6 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPE25597.1 - 2.6e-09 37.4 2.1 4.7e-06 26.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EPE25597.1 - 9.6e-05 21.6 0.1 0.00016 20.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EPE25597.1 - 0.00031 20.0 0.3 0.0006 19.1 0.2 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EPE25597.1 - 0.00034 19.7 0.2 0.0086 15.1 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EPE25597.1 - 0.00036 20.7 0.1 0.012 15.7 0.1 2.6 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE25597.1 - 0.00048 20.1 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EPE25597.1 - 0.0012 18.3 0.1 0.012 14.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EPE25597.1 - 0.0015 17.3 0.0 0.0022 16.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EPE25597.1 - 0.0016 18.5 0.0 0.0035 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPE25597.1 - 0.0031 17.4 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPE25597.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EPE25597.1 - 0.018 15.8 0.0 0.042 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EPE25597.1 - 0.029 14.2 0.0 0.087 12.7 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EPE25597.1 - 0.029 14.3 0.1 0.076 12.9 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EPE25597.1 - 0.033 13.6 0.1 0.088 12.3 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EPE25597.1 - 0.035 14.0 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EPE25597.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_18 PF13238.1 EPE25597.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 EPE25598.1 - 1.1e-16 61.2 0.1 3.1e-16 59.7 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE25598.1 - 1.7e-13 50.8 0.0 2.6e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE25598.1 - 2e-09 37.3 0.6 3.6e-08 33.2 0.4 2.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE25598.1 - 3.8e-08 33.0 0.0 6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE25598.1 - 5.6e-08 32.9 0.0 2.7e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE25598.1 - 2.2e-06 26.6 0.0 1.1e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.1 EPE25598.1 - 0.038 14.2 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_4 PF07993.7 EPE25598.1 - 0.1 11.5 0.1 0.2 10.5 0.0 1.7 1 1 0 1 1 1 0 Male sterility protein NmrA PF05368.8 EPE25598.1 - 0.17 11.1 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Eapp_C PF10238.4 EPE25599.1 - 0.079 12.8 1.0 0.18 11.7 0.5 1.8 1 1 0 1 1 1 0 E2F-associated phosphoprotein Stn1 PF10451.4 EPE25599.1 - 3.3 6.4 6.5 0.94 8.2 0.8 2.3 1 1 0 2 2 2 0 Telomere regulation protein Stn1 SKG6 PF08693.5 EPE25600.1 - 0.00043 19.5 0.0 0.00043 19.5 0.0 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 EPE25600.1 - 0.11 12.1 3.5 0.13 11.9 0.0 2.0 1 1 0 2 2 2 0 Transmembrane protein 51 SpoIIIAH PF12685.2 EPE25600.1 - 0.16 11.4 2.3 0.67 9.4 0.0 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Plasmodium_Vir PF05795.6 EPE25600.1 - 0.2 10.8 0.1 0.26 10.4 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TMEM154 PF15102.1 EPE25600.1 - 0.32 10.6 4.5 1.5 8.5 3.1 2.0 1 1 0 1 1 1 0 TMEM154 protein family DUF2217 PF10265.4 EPE25600.1 - 1.4 7.6 5.0 1.3 7.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) MGC-24 PF05283.6 EPE25600.1 - 4.4 7.0 30.2 36 4.0 20.9 2.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) GMC_oxred_C PF05199.8 EPE25602.1 - 4.9e-29 101.4 0.0 7.6e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EPE25602.1 - 1.4e-26 93.3 0.0 1.9e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EPE25603.1 - 5.7e-23 81.4 0.0 6.8e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EPE25603.1 - 1.6e-05 24.8 0.1 3.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE25603.1 - 0.00013 20.9 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE25603.1 - 0.00015 20.7 0.0 0.00019 20.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EPE25603.1 - 0.0002 19.9 0.0 0.00025 19.6 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EPE25603.1 - 0.0058 15.5 0.1 0.0077 15.1 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPE25603.1 - 0.013 15.5 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE25603.1 - 0.017 15.0 0.4 0.017 15.0 0.3 1.8 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EPE25603.1 - 0.018 15.0 0.4 0.034 14.1 0.3 1.5 1 0 0 1 1 1 0 TrkA-N domain Peptidase_C25_C PF03785.9 EPE25603.1 - 0.019 14.7 0.3 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain Thi4 PF01946.12 EPE25603.1 - 0.02 13.9 0.1 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EPE25603.1 - 0.083 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EPE25603.1 - 0.095 12.4 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pkinase PF00069.20 EPE25604.1 - 1.1e-66 224.7 0.0 1.4e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25604.1 - 6.9e-30 103.9 0.0 1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPE25604.1 - 0.00064 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPE25604.1 - 0.00068 18.6 0.0 0.0041 16.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPE25604.1 - 0.091 12.4 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_transf_28 PF03033.15 EPE25606.1 - 5.8e-22 77.9 0.0 1.8e-21 76.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EPE25606.1 - 5.3e-09 35.1 0.0 1.6e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EPE25606.1 - 0.00023 20.8 0.0 0.00073 19.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain adh_short PF00106.20 EPE25607.1 - 4.6e-19 68.9 0.0 5.8e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE25607.1 - 9.1e-10 38.7 0.0 1.2e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE25607.1 - 3.6e-07 30.0 0.0 6.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Agenet PF05641.7 EPE25607.1 - 0.043 13.9 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 Agenet domain MinC_N PF05209.8 EPE25607.1 - 0.053 13.2 0.2 0.094 12.4 0.1 1.3 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain 3HCDH_N PF02737.13 EPE25607.1 - 0.058 13.0 0.1 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPE25607.1 - 0.064 12.3 0.1 0.53 9.4 0.0 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EPE25607.1 - 0.088 12.6 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EPE25607.1 - 0.098 12.0 0.1 0.28 10.5 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.13 EPE25607.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPE25607.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rav1p_C PF12234.3 EPE25608.1 - 1e-270 899.4 0.3 1.2e-270 899.1 0.2 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EPE25608.1 - 0.00038 20.2 0.5 1.6 8.7 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.3 EPE25608.1 - 0.042 11.9 0.0 0.076 11.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Sfi1 PF08457.5 EPE25609.1 - 3.8e-58 197.2 92.2 4.8e-29 101.2 20.4 3.4 1 1 2 3 3 3 3 Sfi1 spindle body protein tRNA-synt_1 PF00133.17 EPE25610.1 - 2.8e-218 725.7 0.0 4.4e-218 725.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPE25610.1 - 3.5e-26 91.8 0.1 3.2e-25 88.6 0.0 2.4 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EPE25610.1 - 5.8e-18 64.7 0.2 4.4e-07 28.9 0.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EPE25610.1 - 0.0029 16.7 0.0 0.13 11.3 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Glyoxalase_3 PF13468.1 EPE25616.1 - 3.2e-27 95.5 0.0 4e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain MIP PF00230.15 EPE25617.1 - 2.1e-05 24.1 0.4 2.5e-05 23.8 0.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein GFA PF04828.9 EPE25618.1 - 0.0011 18.8 2.1 0.0011 18.8 1.4 2.0 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PRMT5 PF05185.11 EPE25619.1 - 3e-176 586.7 0.0 3.8e-176 586.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase DUF866 PF05907.8 EPE25620.1 - 4.1e-41 140.1 0.1 1e-40 138.8 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.17 EPE25620.1 - 6.8e-18 63.9 0.4 1.2e-17 63.2 0.3 1.3 1 0 0 1 1 1 1 LSM domain PPR_2 PF13041.1 EPE25621.1 - 0.0026 17.6 0.0 0.094 12.7 0.0 2.5 2 0 0 2 2 2 1 PPR repeat family PPR_1 PF12854.2 EPE25621.1 - 0.15 11.5 1.9 0.29 10.6 0.1 2.4 2 0 0 2 2 2 0 PPR repeat adh_short PF00106.20 EPE25622.1 - 6.4e-11 42.4 0.0 8.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE25622.1 - 6.6e-08 32.6 0.0 8.4e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE25622.1 - 0.00034 20.3 0.0 0.00053 19.7 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF460 PF04312.8 EPE25622.1 - 0.017 14.6 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) KOW PF00467.24 EPE25623.1 - 3.4e-08 32.9 1.3 3.4e-08 32.9 0.9 1.7 2 0 0 2 2 2 1 KOW motif Sugar_tr PF00083.19 EPE25624.1 - 4.3e-139 463.9 20.1 5e-139 463.7 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE25624.1 - 8.6e-28 97.0 42.4 1.4e-23 83.1 12.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EPE25624.1 - 0.021 14.7 0.5 0.99 9.4 0.0 3.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 UNC45-central PF11701.3 EPE25625.1 - 1.4e-47 161.2 1.0 2.7e-44 150.5 0.0 4.6 5 1 0 5 5 5 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 EPE25625.1 - 1.3e-06 28.5 7.5 0.058 13.6 0.2 6.0 4 3 1 5 5 5 2 HEAT repeats Arm PF00514.18 EPE25625.1 - 5.1e-05 22.9 7.1 3 7.8 0.0 7.2 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EPE25625.1 - 0.008 16.6 7.5 52 4.5 0.0 6.8 6 1 0 6 6 6 0 HEAT-like repeat Atx10homo_assoc PF09759.4 EPE25625.1 - 0.1 12.3 0.5 8.9 6.1 0.0 3.6 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.17 EPE25625.1 - 0.18 11.9 6.1 25 5.2 0.1 6.0 6 1 0 6 6 6 0 HEAT repeat Tfb4 PF03850.9 EPE25626.1 - 5.6e-109 363.6 0.8 6.4e-109 363.4 0.6 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Asparaginase_2 PF01112.13 EPE25627.1 - 3.8e-34 117.8 4.4 3.7e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Actin PF00022.14 EPE25628.1 - 5.1e-89 298.4 0.0 1.3e-88 297.1 0.0 1.5 1 1 0 1 1 1 1 Actin ADH_N PF08240.7 EPE25629.1 - 8.4e-29 99.5 0.7 8.4e-29 99.5 0.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE25629.1 - 2.5e-27 94.9 0.1 4.2e-27 94.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPE25629.1 - 0.049 12.7 0.1 0.089 11.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.20 EPE25630.1 - 8.3e-71 238.1 0.0 2.3e-70 236.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25630.1 - 1.3e-30 106.3 0.0 2.2e-22 79.3 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPE25630.1 - 5.8e-06 25.4 0.0 0.35 9.7 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EPE25630.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE25630.1 - 0.069 12.8 0.0 1.4 8.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family OB_NTP_bind PF07717.11 EPE25633.1 - 3.6e-26 91.2 0.0 7.9e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPE25633.1 - 2.3e-23 82.1 0.4 7.7e-23 80.4 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPE25633.1 - 1e-10 41.2 0.0 3.1e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPE25633.1 - 7.8e-06 26.0 0.1 4.5e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 EPE25633.1 - 8.8e-06 25.3 0.2 2.4e-05 23.9 0.2 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 EPE25633.1 - 0.0023 17.3 0.0 0.0092 15.4 0.0 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EPE25633.1 - 0.0029 17.4 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 EPE25633.1 - 0.014 14.3 0.0 0.035 13.0 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EPE25633.1 - 0.04 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.11 EPE25633.1 - 0.076 12.2 0.1 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein TFIID_30kDa PF03540.8 EPE25634.1 - 3.9e-24 84.2 0.2 6e-24 83.6 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 EPE25634.1 - 0.093 13.1 0.3 0.21 12.0 0.2 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_S19 PF00203.16 EPE25635.1 - 1.5e-23 82.1 0.0 1.9e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Mre11_DNA_bind PF04152.9 EPE25636.1 - 6.6e-52 175.8 0.1 1e-51 175.2 0.1 1.3 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EPE25636.1 - 6.2e-23 81.2 1.7 8.6e-23 80.7 1.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPE25636.1 - 4.7e-06 26.5 0.0 1.4e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EPE25636.1 - 0.015 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily HD PF01966.17 EPE25637.1 - 1.9e-05 24.6 0.1 3.9e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 HD domain adh_short PF00106.20 EPE25638.1 - 1.3e-14 54.4 0.1 2.6e-14 53.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE25638.1 - 4e-05 23.3 0.0 6.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE25638.1 - 0.002 17.9 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Kinesin PF00225.18 EPE25639.1 - 1.5e-90 303.3 2.3 6e-90 301.3 0.0 2.9 2 1 0 2 2 2 1 Kinesin motor domain IncA PF04156.9 EPE25639.1 - 0.0062 16.1 0.1 0.0062 16.1 0.1 10.8 4 3 3 8 8 8 2 IncA protein Tri3 PF07428.6 EPE25640.1 - 4.8e-18 65.0 0.4 6.6e-17 61.3 0.0 2.7 2 1 0 2 2 2 1 15-O-acetyltransferase Tri3 AATase PF07247.7 EPE25640.1 - 0.0022 16.5 0.1 0.003 16.1 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase ORC6 PF05460.8 EPE25641.1 - 9.5e-41 140.0 9.4 2.7e-39 135.2 1.7 2.0 2 0 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) EF-hand_6 PF13405.1 EPE25642.1 - 5.6e-05 22.6 6.6 0.0017 18.1 0.7 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EPE25642.1 - 0.036 14.2 2.9 0.097 12.8 2.0 1.7 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.1 EPE25642.1 - 0.22 11.1 2.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 EPE25642.1 - 0.43 10.0 0.1 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 EF hand Met_10 PF02475.11 EPE25643.1 - 7.9e-05 22.3 0.0 0.00037 20.1 0.0 2.0 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EPE25643.1 - 0.056 13.4 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HLH PF00010.21 EPE25644.1 - 2.4e-10 39.9 1.3 2.4e-10 39.9 0.9 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DENN PF02141.16 EPE25645.1 - 1.4e-40 139.0 0.1 2.4e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EPE25645.1 - 0.00011 22.1 0.0 0.00032 20.5 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EPE25645.1 - 0.0062 16.9 4.0 0.0062 16.9 2.8 2.3 1 1 1 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2570 PF10828.3 EPE25645.1 - 4.8 6.8 9.9 4.1 7.0 5.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) zf-HIT PF04438.11 EPE25646.1 - 1.2e-09 37.6 10.6 2.1e-09 36.8 7.3 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF829 PF05705.9 EPE25647.1 - 5.9e-31 108.0 0.2 7.5e-31 107.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) His_Phos_2 PF00328.17 EPE25648.1 - 3.3e-07 29.9 0.3 2.3e-06 27.2 0.2 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aldedh PF00171.17 EPE25650.1 - 1.1e-189 630.6 0.7 1.2e-189 630.4 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TRF PF08558.5 EPE25651.1 - 9.4e-63 211.7 0.4 1.5e-62 211.0 0.3 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EPE25651.1 - 6.8e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain FAD_binding_3 PF01494.14 EPE25652.1 - 5.2e-09 35.6 0.0 1.6e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EPE25652.1 - 0.032 13.3 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EPE25652.1 - 0.044 12.6 0.0 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE25652.1 - 0.071 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPE25652.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GBS_Bsp-like PF08481.5 EPE25652.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 GBS Bsp-like repeat Abhydrolase_3 PF07859.8 EPE25653.1 - 2e-63 213.8 0.0 3.5e-63 212.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EPE25653.1 - 4.8e-09 35.4 0.1 1.2e-08 34.1 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EPE25653.1 - 2.3e-06 26.9 0.0 7.6e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EPE25653.1 - 6.7e-05 21.7 0.0 0.00012 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) FLgD_tudor PF13861.1 EPE25653.1 - 0.03 14.3 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 FlgD Tudor-like domain Pkinase PF00069.20 EPE25654.1 - 2.7e-11 43.1 0.0 3.1e-10 39.6 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25654.1 - 0.009 15.1 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE25654.1 - 0.18 10.7 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pyridox_oxidase PF01243.15 EPE25655.1 - 5.8e-11 42.2 0.0 6e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 EPE25655.1 - 3.3e-08 33.5 0.0 9.1e-06 25.7 0.0 2.9 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.6 EPE25655.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_1 PF00175.16 EPE25655.1 - 0.021 15.4 0.0 0.038 14.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain adh_short PF00106.20 EPE25656.1 - 1.2e-25 90.3 0.0 1.6e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE25656.1 - 9.9e-14 51.6 0.0 1.3e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE25656.1 - 5.1e-11 42.5 0.0 7.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPE25656.1 - 0.00053 20.0 0.0 0.00071 19.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EPE25656.1 - 0.0006 19.0 0.0 0.00083 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EPE25656.1 - 0.0019 17.6 0.0 0.0036 16.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPE25656.1 - 0.0034 17.1 0.0 0.0085 15.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EPE25656.1 - 0.011 14.7 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Asparaginase_2 PF01112.13 EPE25657.1 - 1.1e-38 132.7 0.1 1.9e-35 122.1 0.0 3.4 3 1 0 3 3 3 2 Asparaginase SNF2_N PF00176.18 EPE25659.1 - 2.7e-72 243.1 0.0 4.5e-72 242.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC PF07967.8 EPE25659.1 - 4.6e-39 133.2 8.9 9e-35 119.3 0.4 3.5 3 0 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.5 EPE25659.1 - 8.7e-24 83.2 1.5 2.2e-23 81.9 0.1 2.5 2 0 0 2 2 2 1 Rsm1-like Helicase_C PF00271.26 EPE25659.1 - 3.1e-11 42.9 0.0 6.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BIR PF00653.16 EPE25659.1 - 0.011 16.1 6.7 0.011 16.0 0.1 3.2 3 1 0 3 3 3 0 Inhibitor of Apoptosis domain DEAD_2 PF06733.10 EPE25659.1 - 0.024 14.0 1.8 0.026 13.9 0.0 2.0 2 0 0 2 2 2 0 DEAD_2 Inositol_P PF00459.20 EPE25660.1 - 2.5e-51 174.5 3.4 4.8e-51 173.6 2.4 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.18 EPE25661.1 - 1.3e-24 86.5 1.3 1.3e-12 48.0 0.0 3.2 4 0 0 4 4 4 2 Ribosomal protein L6 HET PF06985.6 EPE25662.1 - 4.5e-23 81.9 3.6 7.3e-23 81.2 2.5 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ICL PF00463.16 EPE25664.1 - 2.6e-196 652.9 0.1 3e-196 652.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EPE25664.1 - 6.3e-12 45.2 0.1 3.4e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 EPE25664.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Citrate_synt PF00285.16 EPE25665.1 - 2.5e-103 345.5 0.0 2.9e-103 345.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Glyco_hydro_98M PF08306.6 EPE25665.1 - 0.043 12.5 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 WSC PF01822.14 EPE25666.1 - 2.6e-47 158.6 34.9 1.8e-18 66.2 3.9 3.8 3 0 0 3 3 3 3 WSC domain PQQ_3 PF13570.1 EPE25666.1 - 2.9e-05 24.1 4.7 0.078 13.2 0.0 5.0 4 0 0 4 4 4 2 PQQ-like domain SnoaL_2 PF12680.2 EPE25667.1 - 0.00021 21.6 0.1 0.00027 21.2 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.11 EPE25668.1 - 4.6e-37 127.5 26.6 4.6e-37 127.5 18.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE25668.1 - 3.9e-06 25.3 5.9 7.9e-06 24.3 4.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ADH_N PF08240.7 EPE25669.1 - 2.4e-07 30.4 0.0 4.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain cwf18 PF08315.7 EPE25670.1 - 0.026 14.9 2.4 0.059 13.8 1.7 1.6 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor CD99L2 PF12301.3 EPE25670.1 - 1.6 8.4 6.3 0.34 10.5 2.0 1.6 2 0 0 2 2 2 0 CD99 antigen like protein 2 Tautomerase_3 PF14832.1 EPE25671.1 - 9.7e-10 38.5 0.0 1.9e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme WVELL PF14043.1 EPE25671.1 - 0.056 13.0 0.4 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 WVELL protein Peptidase_M19 PF01244.16 EPE25672.1 - 3.4e-98 328.5 0.0 3.9e-98 328.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Imm42 PF15601.1 EPE25672.1 - 0.027 13.8 0.1 0.086 12.2 0.1 1.8 1 1 0 1 1 1 0 Immunity protein 42 p450 PF00067.17 EPE25673.1 - 2.6e-20 72.4 0.0 3.3e-19 68.7 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 PAP2_3 PF14378.1 EPE25673.1 - 0.51 9.8 2.0 1.1 8.7 1.4 1.6 1 0 0 1 1 1 0 PAP2 superfamily zf-CCCH PF00642.19 EPE25675.1 - 3e-05 23.5 3.5 3e-05 23.5 2.5 2.4 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cwf_Cwc_15 PF04889.7 EPE25675.1 - 0.0032 17.2 6.1 0.0032 17.2 4.2 2.6 2 1 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Ost4 PF10215.4 EPE25676.1 - 1.3e-15 56.5 0.5 1.6e-15 56.3 0.4 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase Sugar_transport PF06800.7 EPE25676.1 - 0.099 11.7 0.1 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Sugar transport protein RRM_1 PF00076.17 EPE25677.1 - 1e-13 50.6 0.0 1.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE25677.1 - 4.5e-11 42.5 0.0 7.5e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EPE25677.1 - 0.00012 22.4 1.3 0.00012 22.4 0.9 2.9 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EPE25677.1 - 0.039 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cutinase PF01083.17 EPE25678.1 - 1e-48 165.4 0.8 1.3e-48 165.1 0.6 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 EPE25678.1 - 0.006 16.3 0.1 0.009 15.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 EPE25678.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_1 PF00561.15 EPE25678.1 - 0.032 13.7 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold TM_helix PF05552.7 EPE25678.1 - 0.092 12.4 0.2 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 Conserved TM helix Lipase_3 PF01764.20 EPE25678.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.3 1 1 0 1 1 1 0 Lipase (class 3) AAA PF00004.24 EPE25679.1 - 2e-18 66.8 0.1 5.9e-18 65.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE25679.1 - 4.5e-05 24.2 0.6 0.0028 18.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE25679.1 - 0.00067 19.8 0.2 0.0076 16.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EPE25679.1 - 0.0035 17.3 0.1 0.0087 16.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EPE25679.1 - 0.01 16.1 0.0 0.065 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPE25679.1 - 0.016 14.9 0.2 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 EPE25679.1 - 0.02 13.9 0.0 0.065 12.2 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPE25679.1 - 0.024 14.3 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPE25679.1 - 0.058 13.2 0.0 0.3 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EPE25679.1 - 0.075 12.9 0.0 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EPE25679.1 - 0.077 12.4 0.2 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein KaiC PF06745.8 EPE25679.1 - 0.13 11.3 0.9 0.5 9.4 0.2 2.0 1 1 1 2 2 2 0 KaiC Benyvirus_P25 PF05744.6 EPE25680.1 - 0.069 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Benyvirus P25/P26 protein SNF2_N PF00176.18 EPE25681.1 - 8.6e-34 116.6 0.0 8.7e-31 106.8 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE25681.1 - 1.5e-08 34.3 0.0 3.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EPE25681.1 - 7.1e-05 22.4 9.4 0.00015 21.4 6.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPE25681.1 - 0.00068 19.4 8.6 0.00068 19.4 5.9 2.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EPE25681.1 - 0.0069 16.0 10.1 0.016 14.8 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EPE25681.1 - 0.063 13.1 4.9 0.15 11.9 3.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4_2 PF13923.1 EPE25681.1 - 0.79 9.8 13.4 0.13 12.3 6.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EPE25681.1 - 2 8.2 4.8 6.3 6.6 3.3 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EPE25681.1 - 2.2 7.8 7.3 4.8 6.8 0.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Snf7 PF03357.16 EPE25682.1 - 5.3e-25 87.7 8.1 5.3e-25 87.7 5.6 1.7 1 1 1 2 2 2 1 Snf7 CS PF04969.11 EPE25683.1 - 2.9e-07 30.9 0.2 4.9e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 CS domain PIH1 PF08190.7 EPE25683.1 - 0.0058 16.1 0.5 0.01 15.3 0.1 1.5 2 0 0 2 2 2 1 pre-RNA processing PIH1/Nop17 CENP-B_dimeris PF09026.5 EPE25683.1 - 8 6.7 13.0 11 6.3 4.3 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RabGAP-TBC PF00566.13 EPE25684.1 - 4.5e-49 166.8 0.1 7e-49 166.1 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain adh_short_C2 PF13561.1 EPE25685.1 - 3.4e-30 105.5 2.0 4.1e-30 105.3 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE25685.1 - 1.3e-26 93.4 1.2 1.8e-26 93.0 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE25685.1 - 8.8e-11 41.7 0.7 1.8e-10 40.8 0.5 1.5 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 EPE25685.1 - 0.11 12.8 0.1 0.29 11.5 0.1 1.6 1 1 1 2 2 2 0 Methyltransferase domain Rick_17kDa_Anti PF05433.10 EPE25689.1 - 0.091 12.4 15.1 0.2 11.3 10.5 1.6 1 1 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EPE25689.1 - 6 6.4 15.5 17 5.0 10.7 1.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 EPE25689.1 - 9.3 5.9 9.5 2.6 7.7 2.1 2.4 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 EPE25689.1 - 9.9 5.8 15.7 0.72 9.5 2.8 2.2 1 1 1 2 2 2 0 Glycine zipper Amidohydro_5 PF13594.1 EPE25691.1 - 0.064 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Amidohydrolase tRNA_int_end_N2 PF12928.2 EPE25692.1 - 1.7e-25 88.2 0.0 3e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EPE25692.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Arrestin_C PF02752.17 EPE25693.1 - 2.1e-13 50.5 0.3 8.5e-13 48.5 0.0 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 EPE25694.1 - 2.1e-48 164.4 0.1 2.4e-48 164.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAP2 PF01569.16 EPE25695.1 - 2.1e-19 69.4 2.1 7.5e-19 67.6 1.5 1.9 1 0 0 1 1 1 1 PAP2 superfamily DUF566 PF04484.7 EPE25695.1 - 0.28 10.6 1.8 0.41 10.0 1.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ras PF00071.17 EPE25696.1 - 3.4e-48 163.0 0.0 4.5e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE25696.1 - 3e-12 47.1 0.0 4.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE25696.1 - 4.2e-05 22.8 0.0 7.2e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPE25696.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DASH_Dad1 PF08649.5 EPE25697.1 - 7.5e-25 86.3 1.5 9.5e-25 86.0 1.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 PTR2 PF00854.16 EPE25698.1 - 3.2e-27 95.3 7.6 4.9e-14 51.9 2.1 2.2 2 0 0 2 2 2 2 POT family TMF_DNA_bd PF12329.3 EPE25700.1 - 1.6e-07 31.0 5.9 1.6e-07 31.0 4.1 2.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding DUF4404 PF14357.1 EPE25700.1 - 0.4 11.1 3.7 0.59 10.5 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) TMPIT PF07851.8 EPE25700.1 - 0.67 8.9 2.8 1.1 8.1 1.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF4200 PF13863.1 EPE25700.1 - 0.74 9.7 14.8 0.024 14.6 4.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG6 PF04111.7 EPE25700.1 - 1.5 7.7 9.1 3.1 6.7 6.3 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 GDPD PF03009.12 EPE25701.1 - 6.2e-72 242.1 0.0 1.7e-71 240.7 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EPE25701.1 - 3.3e-33 113.8 0.6 9.3e-13 48.3 0.2 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE25701.1 - 3.6e-27 94.2 2.0 3.3e-09 37.0 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EPE25701.1 - 4.4e-26 89.3 6.2 2.4e-07 30.2 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat SPX PF03105.14 EPE25701.1 - 1.7e-25 90.3 3.1 1.8e-12 47.6 0.6 3.5 1 1 1 2 2 2 2 SPX domain Ank_5 PF13857.1 EPE25701.1 - 4.6e-25 87.0 3.5 8.5e-09 35.3 0.0 6.5 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE25701.1 - 6.4e-16 56.8 1.4 0.0012 18.8 0.0 6.4 5 0 0 5 5 5 2 Ankyrin repeat DBR1 PF05011.8 EPE25702.1 - 3.2e-48 163.3 0.0 5.8e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EPE25702.1 - 4.5e-08 32.7 0.8 6.8e-08 32.1 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rpr2 PF04032.11 EPE25703.1 - 2.7e-10 39.9 4.0 2.7e-10 39.9 2.7 1.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Basic PF01586.11 EPE25703.1 - 0.022 15.4 2.2 0.047 14.4 1.5 1.7 1 0 0 1 1 1 0 Myogenic Basic domain DUF4551 PF15087.1 EPE25703.1 - 0.95 7.7 3.9 1.1 7.5 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-ZPR1 PF03367.8 EPE25704.1 - 1.8e-104 345.8 0.0 1.1e-52 177.4 0.0 2.4 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-C2H2 PF00096.21 EPE25707.1 - 1.3e-11 44.1 10.5 5.5e-06 26.4 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPE25707.1 - 1.4e-09 37.7 10.1 1.9e-06 27.8 1.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPE25707.1 - 1.9e-09 37.1 7.2 7.9e-05 22.7 0.1 2.9 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EPE25707.1 - 0.0037 17.4 7.0 0.39 10.9 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EPE25707.1 - 0.0064 16.3 3.4 0.24 11.3 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EPE25707.1 - 0.037 14.2 1.5 0.037 14.2 1.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EPE25707.1 - 0.039 14.1 0.0 0.039 14.1 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EPE25707.1 - 2.5 7.9 10.3 0.39 10.5 0.6 3.0 2 1 1 3 3 3 0 BED zinc finger Pkinase PF00069.20 EPE25708.1 - 2.8e-74 249.5 0.0 4.6e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25708.1 - 4.5e-34 117.7 0.0 2.5e-32 111.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE25708.1 - 0.00013 21.0 0.0 0.00029 19.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPE25708.1 - 0.0016 17.5 0.0 0.0038 16.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE25708.1 - 0.0077 15.9 0.0 0.024 14.3 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE25708.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase SMC_N PF02463.14 EPE25709.1 - 3.2e-24 85.3 0.0 5.2e-24 84.6 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPE25709.1 - 1.2e-18 68.1 0.0 1.2e-18 68.1 0.0 5.2 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EPE25709.1 - 4.3e-08 33.4 0.2 0.00058 19.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EPE25709.1 - 0.00088 18.7 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EPE25709.1 - 0.015 14.5 7.4 0.25 10.4 0.1 3.9 3 1 1 4 4 4 0 Reovirus sigma C capsid protein AAA PF00004.24 EPE25709.1 - 0.075 13.2 1.8 0.25 11.5 0.0 2.9 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EPE25709.1 - 0.19 11.0 0.0 0.19 11.0 0.0 3.7 4 1 1 5 5 5 0 AAA domain ABC_tran PF00005.22 EPE25709.1 - 0.57 10.4 0.0 0.57 10.4 0.0 5.4 3 2 0 4 4 4 0 ABC transporter NPV_P10 PF05531.7 EPE25709.1 - 0.76 10.0 23.7 2.1 8.6 0.7 6.9 5 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Ctr PF04145.10 EPE25712.1 - 5.1e-29 101.1 1.2 6.1e-29 100.9 0.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4134 PF13572.1 EPE25712.1 - 0.021 14.9 0.5 0.054 13.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) FAD_binding_8 PF08022.7 EPE25713.1 - 2.1e-18 66.0 0.0 4.8e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EPE25713.1 - 2.9e-17 62.9 7.3 2.9e-17 62.9 5.1 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EPE25713.1 - 9.4e-16 58.0 0.0 1.5e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EPE25713.1 - 0.0021 18.1 0.0 0.0092 16.0 0.0 2.1 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain Lyase_1 PF00206.15 EPE25714.1 - 1.2e-109 366.3 0.0 1.9e-109 365.6 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EPE25714.1 - 6.9e-22 77.2 0.0 1.6e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Malate_synthase PF01274.17 EPE25715.1 - 3.7e-232 770.9 0.0 4.2e-232 770.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase FAD_binding_3 PF01494.14 EPE25718.1 - 1.4e-25 90.1 0.0 2.9e-25 89.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EPE25718.1 - 3.3e-05 22.8 0.0 0.00038 19.3 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 EPE25718.1 - 0.0004 19.4 0.0 0.0017 17.3 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EPE25718.1 - 0.0017 17.3 0.0 1 8.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE25718.1 - 0.0095 15.9 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE25718.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE25718.1 - 0.023 14.5 0.2 0.07 12.8 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EPE25718.1 - 0.05 12.2 0.5 2 6.9 0.1 2.6 2 1 1 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 EPE25718.1 - 0.12 10.8 0.0 0.44 8.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein DUF2428 PF10350.4 EPE25720.1 - 0.0025 16.8 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) Tetraspannin PF00335.15 EPE25721.1 - 7.6e-08 31.8 8.1 1.1e-07 31.3 5.6 1.1 1 0 0 1 1 1 1 Tetraspanin family PepSY_TM_1 PF13172.1 EPE25721.1 - 0.12 12.1 0.4 0.12 12.1 0.3 2.7 2 0 0 2 2 2 0 PepSY-associated TM helix DUF3810 PF12725.2 EPE25721.1 - 1.3 7.8 4.0 21 3.8 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Cytochrom_B561 PF03188.11 EPE25721.1 - 2.1 8.2 6.5 0.2 11.5 1.3 1.7 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 FeoB_C PF07664.7 EPE25721.1 - 5.5 6.5 0.0 5.5 6.5 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus SRF-TF PF00319.13 EPE25722.1 - 1.1e-08 34.2 0.1 1.6e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Mg_trans_NIPA PF05653.9 EPE25723.1 - 5.4e-14 51.8 5.3 9e-14 51.1 3.6 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EPE25723.1 - 0.00012 22.0 18.0 0.0027 17.7 0.0 3.3 2 1 1 3 3 3 2 EamA-like transporter family vATP-synt_E PF01991.13 EPE25724.1 - 1e-61 207.7 10.0 1.2e-61 207.4 6.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit MRP-63 PF14978.1 EPE25724.1 - 5.4 7.5 6.5 1.4 9.3 1.8 2.0 1 1 2 3 3 3 0 Mitochondrial ribosome protein 63 Phe_tRNA-synt_N PF02912.13 EPE25724.1 - 5.4 6.8 9.4 0.35 10.6 0.1 3.5 4 1 1 5 5 5 0 Aminoacyl tRNA synthetase class II, N-terminal domain FAM178 PF14816.1 EPE25725.1 - 1 7.9 7.2 0.11 11.1 0.8 2.3 2 1 1 3 3 3 0 Family of unknown function, FAM178 E1-E2_ATPase PF00122.15 EPE25726.1 - 3.9e-15 55.5 2.3 1.8e-14 53.3 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 EPE25726.1 - 2e-12 47.6 0.4 1.1e-11 45.3 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPE25726.1 - 2.3e-12 46.6 0.0 7.2e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EPE25726.1 - 5.8e-12 46.4 2.2 3.5e-10 40.6 1.6 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPE25726.1 - 0.007 15.9 1.9 0.011 15.2 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Apo-CII PF05355.6 EPE25726.1 - 0.27 11.1 0.8 0.58 10.0 0.0 1.9 2 0 0 2 2 2 0 Apolipoprotein C-II SEN1_N PF12726.2 EPE25727.1 - 1.1e-176 589.0 1.3 1.6e-176 588.5 0.9 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EPE25727.1 - 6.8e-66 222.2 0.6 6.8e-66 222.2 0.4 2.3 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EPE25727.1 - 9.3e-63 211.2 0.0 1.9e-62 210.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE25727.1 - 4.9e-10 39.0 0.0 1.5e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPE25727.1 - 2.7e-07 30.3 0.1 8.1e-05 22.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EPE25727.1 - 5.4e-07 29.3 0.1 0.0049 16.4 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EPE25727.1 - 2.5e-06 27.0 0.5 0.022 14.0 0.0 3.1 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EPE25727.1 - 0.00028 20.4 0.2 0.0092 15.4 0.0 2.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_23 PF13476.1 EPE25727.1 - 0.0056 17.0 3.2 0.023 15.0 1.1 2.9 2 1 0 2 2 2 1 AAA domain OmpH PF03938.9 EPE25727.1 - 7.6 6.4 16.9 6.1 6.7 6.1 3.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Pectate_lyase PF03211.8 EPE25729.1 - 9.2e-64 214.7 8.3 1.1e-63 214.5 5.7 1.0 1 0 0 1 1 1 1 Pectate lyase Phosphoesterase PF04185.9 EPE25730.1 - 2.8e-35 122.2 3.9 9.8e-35 120.4 1.8 2.2 1 1 1 2 2 2 1 Phosphoesterase family PI3K_rbd PF00794.13 EPE25730.1 - 0.018 15.0 0.0 0.08 12.8 0.0 2.1 2 0 0 2 2 2 0 PI3-kinase family, ras-binding domain GH114_assoc PF14741.1 EPE25730.1 - 0.026 14.2 0.1 0.072 12.8 0.1 1.7 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain DUF3670 PF12419.3 EPE25731.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 SNF2 Helicase protein Metallophos PF00149.23 EPE25732.1 - 5e-10 39.0 1.6 9.2e-10 38.2 1.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EPE25732.1 - 0.0086 16.0 0.0 0.094 12.6 0.0 2.3 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain PHO4 PF01384.15 EPE25733.1 - 4.4e-118 393.6 14.8 5.3e-118 393.3 10.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family Fungal_trans PF04082.13 EPE25734.1 - 4.4e-33 114.2 0.5 6.3e-33 113.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 EPE25734.1 - 1.1e-09 37.8 2.9 3.6e-05 22.9 1.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EPE25734.1 - 4.7e-05 22.4 0.9 0.0066 15.4 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPE25734.1 - 0.00044 20.5 0.6 0.0016 18.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE25734.1 - 0.00047 19.1 1.4 0.001 17.9 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EPE25734.1 - 0.0051 15.3 0.4 0.012 14.1 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EPE25734.1 - 0.014 15.2 0.8 0.052 13.4 0.6 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE25734.1 - 0.12 12.3 0.3 0.3 11.1 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-C2H2 PF00096.21 EPE25735.1 - 0.00037 20.6 15.5 0.0092 16.2 0.4 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE25735.1 - 0.0069 16.6 11.3 0.46 10.9 0.0 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger Transpos_assoc PF13963.1 EPE25735.1 - 0.092 12.7 0.1 0.31 11.0 0.1 1.8 1 0 0 1 1 1 0 Transposase-associated domain zf-BED PF02892.10 EPE25735.1 - 2.1 8.1 12.2 2.7 7.8 1.4 3.1 3 0 0 3 3 3 0 BED zinc finger DUF3446 PF11928.3 EPE25736.1 - 1.3 9.2 7.6 1.6 9.0 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) BNIP3 PF06553.7 EPE25736.1 - 4.6 6.5 8.4 5.3 6.3 5.8 1.0 1 0 0 1 1 1 0 BNIP3 Oxidored_FMN PF00724.15 EPE25737.1 - 6.1e-64 216.1 0.0 7.9e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NTP_transferase PF00483.18 EPE25738.1 - 3.1e-28 98.7 0.0 4e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EPE25738.1 - 1.7e-10 39.9 7.0 2.4e-06 26.7 0.0 3.9 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EPE25738.1 - 3.6e-07 30.3 0.0 5.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EPE25738.1 - 0.049 13.1 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.1 EPE25738.1 - 0.12 11.9 3.7 1.4 8.5 0.0 3.8 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Dynamin_N PF00350.18 EPE25739.1 - 2e-21 76.5 0.0 5.6e-21 75.0 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EPE25739.1 - 2e-12 46.5 0.1 5.1e-10 38.5 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EPE25739.1 - 3.7e-06 26.7 1.3 8.8e-06 25.5 0.2 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 EPE25739.1 - 0.001 19.5 0.2 0.0099 16.3 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein ABC_tran PF00005.22 EPE25739.1 - 0.0012 19.1 0.0 0.0051 17.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 EPE25739.1 - 0.0014 18.6 0.0 1.3 8.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EPE25739.1 - 0.0031 17.4 0.0 0.038 13.9 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.1 EPE25739.1 - 0.024 14.5 1.2 0.036 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EPE25739.1 - 0.03 13.8 0.2 0.072 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MFS_1 PF07690.11 EPE25740.1 - 8.6e-19 67.4 24.4 2.8e-17 62.4 1.2 3.2 3 1 0 3 3 3 2 Major Facilitator Superfamily MgtC PF02308.11 EPE25740.1 - 0.0056 16.5 0.3 0.014 15.2 0.2 1.6 1 0 0 1 1 1 1 MgtC family TraQ PF09679.5 EPE25740.1 - 0.12 12.3 0.2 0.83 9.6 0.0 2.5 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) FAD_binding_7 PF03441.9 EPE25741.1 - 8.9e-58 195.6 0.0 1.3e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EPE25741.1 - 6.2e-22 78.0 0.0 1.1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Coatomer_E PF04733.9 EPE25741.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit Pkinase PF00069.20 EPE25744.1 - 5.1e-27 94.6 0.0 1.9e-26 92.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25744.1 - 1.5e-11 43.8 0.0 1.3e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPE25744.1 - 0.024 13.6 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Peptidase_M20 PF01546.23 EPE25747.1 - 1.7e-21 76.6 0.0 9.5e-21 74.1 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EPE25747.1 - 1.5e-12 46.8 6.6 0.00057 19.6 0.0 5.8 7 0 0 7 7 7 3 WD domain, G-beta repeat M20_dimer PF07687.9 EPE25747.1 - 1.9e-06 27.5 0.0 3.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain PQQ_3 PF13570.1 EPE25747.1 - 0.045 14.0 0.9 0.74 10.1 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain DUF747 PF05346.6 EPE25748.1 - 3.3e-132 440.5 6.7 4.2e-132 440.2 4.6 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Uso1_p115_head PF04869.9 EPE25749.1 - 5.9e-108 360.3 0.0 2.4e-107 358.3 0.0 2.0 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EPE25749.1 - 7.5e-10 38.8 29.3 7.5e-10 38.8 20.3 3.4 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Arm PF00514.18 EPE25749.1 - 0.00053 19.7 0.0 3.3 7.6 0.0 3.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat XRN_N PF03159.13 EPE25750.1 - 3.9e-110 366.8 0.0 6.1e-110 366.2 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus UDPG_MGDP_dh_N PF03721.9 EPE25750.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-CCHC PF00098.18 EPE25750.1 - 0.19 11.7 3.6 0.34 10.9 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EPE25750.1 - 0.36 10.5 0.7 1.5 8.5 0.7 1.9 2 0 0 2 2 2 0 Zinc knuckle RasGAP PF00616.14 EPE25751.1 - 1.7e-46 158.3 0.0 3.1e-46 157.5 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EPE25751.1 - 2.2e-07 30.9 0.0 6e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2419 PF10343.4 EPE25752.1 - 1.9e-129 431.0 0.2 2.6e-129 430.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Methyltransf_11 PF08241.7 EPE25752.1 - 0.085 13.3 0.1 15 6.1 0.1 2.4 2 0 0 2 2 2 0 Methyltransferase domain ThiF PF00899.16 EPE25753.1 - 1.2e-41 141.6 0.2 2.8e-41 140.5 0.1 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EPE25753.1 - 2.3e-30 103.9 0.1 4.6e-30 102.9 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EPE25753.1 - 5e-19 68.1 0.3 1.3e-18 66.8 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EPE25753.1 - 0.00088 19.4 0.1 0.0029 17.8 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EPE25753.1 - 0.0084 16.2 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EPE25754.1 - 5e-28 98.0 0.5 7.2e-28 97.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE25754.1 - 2.5e-17 63.4 0.0 3.4e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE25754.1 - 1.3e-07 31.4 0.2 2.4e-07 30.5 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE25754.1 - 0.0022 17.4 0.0 0.063 12.6 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE25754.1 - 0.0027 17.7 0.3 0.0072 16.3 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EPE25754.1 - 0.023 14.4 0.2 0.023 14.4 0.1 2.2 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PAP2 PF01569.16 EPE25755.1 - 7.6e-10 38.5 9.1 7.6e-10 38.5 6.3 2.2 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EPE25755.1 - 1.6e-06 27.7 6.0 1.8e-06 27.5 3.4 1.6 1 1 0 1 1 1 1 PAP2 superfamily Peptidase_M50 PF02163.17 EPE25755.1 - 0.032 13.1 1.4 0.057 12.3 0.3 1.8 2 0 0 2 2 2 0 Peptidase family M50 PAP2_C PF14360.1 EPE25755.1 - 5.4 7.3 9.5 0.39 11.0 1.8 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Skp1_POZ PF03931.10 EPE25756.1 - 4.3e-08 33.1 0.0 2e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Amidase PF01425.16 EPE25757.1 - 3.4e-86 289.8 0.0 4.1e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Amidase DNA_pol_delta_4 PF04081.8 EPE25758.1 - 7.3e-24 84.4 0.2 1.4e-23 83.5 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Seryl_tRNA_N PF02403.17 EPE25758.1 - 0.58 10.1 3.9 0.97 9.4 2.7 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Citrate_synt PF00285.16 EPE25759.1 - 6e-18 64.6 0.0 2.8e-15 55.9 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EPE25759.1 - 2.4e-17 63.2 0.0 8.8e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EPE25759.1 - 1.7e-14 53.6 0.0 2.9e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EPE25759.1 - 1.9e-05 24.2 0.0 0.00015 21.3 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CEP1-DNA_bind PF09287.5 EPE25759.1 - 0.2 11.0 0.0 0.46 9.8 0.0 1.5 1 0 0 1 1 1 0 CEP-1, DNA binding ATP-grasp_2 PF08442.5 EPE25760.1 - 4e-08 32.8 0.0 7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Glyco_hydro_72 PF03198.9 EPE25761.1 - 1e-113 379.4 0.0 1.3e-113 379.1 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EPE25761.1 - 4.2e-05 22.5 0.0 6.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain HALZ PF02183.13 EPE25761.1 - 0.18 11.5 0.6 0.57 9.9 0.2 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Mito_carr PF00153.22 EPE25762.1 - 7.4e-57 189.0 4.9 5.8e-23 80.4 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EPE25762.1 - 1.6e-23 82.6 1.4 9.9e-13 48.0 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EPE25762.1 - 1.1e-19 68.1 7.4 3.2e-06 26.0 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EPE25762.1 - 1.3e-17 61.9 5.3 9.3e-05 21.9 0.3 4.8 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 EPE25762.1 - 6.8e-15 54.4 2.0 2.4e-06 27.0 0.0 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EPE25762.1 - 5.4e-12 44.4 7.9 0.00034 19.8 0.1 3.8 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.4 EPE25762.1 - 1.4e-05 25.0 0.0 0.0095 15.9 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EPE25762.1 - 0.92 9.2 4.1 9 6.0 0.1 3.5 4 0 0 4 4 4 0 EF hand Cyclin_N PF00134.18 EPE25763.1 - 1.3e-10 40.9 0.0 2.9e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 EPE25763.1 - 0.025 14.3 0.3 0.077 12.8 0.2 1.9 1 1 0 1 1 1 0 Transcription factor TFIIB repeat CRAL_TRIO_N PF03765.10 EPE25763.1 - 0.042 13.9 0.1 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain DUF4452 PF14618.1 EPE25765.1 - 2.1e-62 209.7 8.7 2.7e-62 209.4 6.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) U79_P34 PF03064.11 EPE25766.1 - 4.3 6.7 10.4 4.7 6.6 7.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SNARE PF05739.14 EPE25767.1 - 1.7e-13 49.9 4.8 3.8e-13 48.8 3.4 1.6 1 0 0 1 1 1 1 SNARE domain Rifin_STEVOR PF02009.11 EPE25767.1 - 0.019 14.6 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 Rifin/stevor family ING PF12998.2 EPE25767.1 - 0.07 13.4 4.1 0.076 13.2 2.0 1.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF912 PF06024.7 EPE25767.1 - 0.097 12.7 1.0 0.23 11.5 0.4 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Serine_rich PF08824.5 EPE25767.1 - 0.84 9.3 5.0 1.3 8.7 0.3 2.5 2 1 0 2 2 2 0 Serine rich protein interaction domain Use1 PF09753.4 EPE25767.1 - 0.99 8.7 5.3 1.7 7.9 3.7 1.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 Synaptobrevin PF00957.16 EPE25767.1 - 8.3 6.0 10.1 4.2 7.0 4.7 2.3 2 1 0 2 2 2 0 Synaptobrevin zf-TRAF PF02176.13 EPE25768.1 - 9.7e-11 41.8 29.3 8.3e-05 22.8 2.1 4.2 1 1 3 4 4 4 3 TRAF-type zinc finger zf-RING_2 PF13639.1 EPE25768.1 - 9.2e-08 31.7 8.7 9.2e-08 31.7 6.1 3.9 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE25768.1 - 1.5e-07 31.2 8.1 1.5e-07 31.2 5.6 4.1 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE25768.1 - 3.9e-07 29.6 6.9 3.9e-07 29.6 4.8 4.6 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE25768.1 - 2.8e-06 26.9 5.8 2.8e-06 26.9 4.0 3.9 3 1 1 4 4 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE25768.1 - 3.5e-05 23.3 5.1 3.5e-05 23.3 3.5 4.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPE25768.1 - 5.5e-05 22.7 5.0 5.5e-05 22.7 3.5 3.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EPE25768.1 - 0.00053 19.8 9.4 0.00053 19.8 6.5 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EPE25768.1 - 0.0024 17.9 3.2 0.0024 17.9 2.2 3.9 2 2 0 2 2 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EPE25768.1 - 0.0058 16.3 3.3 0.0058 16.3 2.3 3.0 2 1 1 3 3 3 1 zf-RING of BARD1-type protein U-box PF04564.10 EPE25768.1 - 0.018 14.9 0.0 0.13 12.2 0.0 2.3 3 0 0 3 3 3 0 U-box domain zf-Nse PF11789.3 EPE25768.1 - 0.82 9.2 15.9 1.4 8.4 9.2 2.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ATP_bind_3 PF01171.15 EPE25769.1 - 3.4e-45 153.7 0.0 6.3e-45 152.8 0.0 1.4 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 EPE25769.1 - 0.0018 17.8 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 EPE25769.1 - 0.0041 15.7 0.3 0.013 14.0 0.0 1.8 2 0 0 2 2 2 1 tRNA methyl transferase NAD_synthase PF02540.12 EPE25769.1 - 0.021 13.7 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Mito_carr PF00153.22 EPE25770.1 - 1.6e-50 168.7 7.6 2.9e-18 65.3 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 EPE25770.1 - 0.078 13.3 0.5 4.3 7.7 0.0 2.6 2 0 0 2 2 2 0 YtxH-like protein DUF3337 PF11816.3 EPE25771.1 - 1.4e-90 304.0 0.0 9.7e-88 294.7 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EPE25771.1 - 6.8e-29 98.6 11.2 4e-07 29.6 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Peptidase_C48 PF02902.14 EPE25772.1 - 7.7e-21 74.7 0.0 1.8e-20 73.5 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FAD_binding_3 PF01494.14 EPE25773.1 - 1e-72 245.1 0.0 1.3e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EPE25773.1 - 3.8e-44 150.2 0.0 6.7e-44 149.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EPE25773.1 - 0.0012 19.1 0.0 0.019 15.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE25773.1 - 0.0034 16.3 0.0 0.0078 15.1 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EPE25773.1 - 0.018 13.9 0.0 0.26 10.1 0.0 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EPE25773.1 - 0.021 13.9 0.0 0.052 12.6 0.0 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 EPE25773.1 - 0.025 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE25773.1 - 0.032 14.0 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EPE25773.1 - 0.036 13.5 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 EPE25773.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.9 EPE25773.1 - 0.091 12.1 0.2 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EPE25773.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 ThiF family DDHD PF02862.12 EPE25775.1 - 2.2e-41 142.1 17.3 7.5e-27 94.5 0.0 4.7 3 1 1 4 4 4 2 DDHD domain DSBA PF01323.15 EPE25776.1 - 5.1e-17 62.0 0.0 6e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain zf-C2H2 PF00096.21 EPE25779.1 - 1.5e-13 50.2 22.0 0.00035 20.7 1.2 4.0 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE25779.1 - 2.5e-10 39.9 18.2 0.00098 19.2 1.0 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE25779.1 - 1.8e-05 24.7 23.7 0.00071 19.7 1.8 4.2 4 1 1 5 5 5 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 EPE25779.1 - 0.009 16.1 0.4 0.009 16.1 0.3 3.9 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EPE25779.1 - 0.18 12.0 15.4 0.33 11.1 0.6 4.3 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EPE25779.1 - 2.6 8.4 12.0 1.7 9.0 4.7 2.8 1 1 2 3 3 3 0 TRAF-type zinc finger WD40 PF00400.27 EPE25781.1 - 8.1e-06 25.5 2.8 0.0014 18.4 0.0 3.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EPE25781.1 - 0.15 11.5 0.0 17 5.0 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cupin_8 PF13621.1 EPE25782.1 - 1.2e-36 126.5 0.0 1.8e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 EPE25782.1 - 6.9e-17 61.5 0.0 1.4e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 EPE25782.1 - 6.2e-06 25.8 12.8 0.00012 21.7 0.1 5.2 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 EPE25782.1 - 0.00016 21.1 6.9 0.5 9.9 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Cupin_4 PF08007.7 EPE25782.1 - 0.00031 20.0 0.0 0.00059 19.1 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_3 PF13415.1 EPE25782.1 - 0.0012 18.9 1.5 0.22 11.7 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 EPE25782.1 - 0.016 15.1 7.1 2.3 8.2 0.1 4.7 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 EPE25782.1 - 0.28 11.4 12.8 10 6.5 0.1 4.9 3 1 1 4 4 4 0 Kelch motif MFS_1 PF07690.11 EPE25783.1 - 1.3e-24 86.6 67.8 3.3e-17 62.2 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_Rpb1_5 PF04998.12 EPE25784.1 - 1.6e-85 286.7 0.0 1.5e-84 283.5 0.0 2.5 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPE25784.1 - 1.9e-63 213.3 0.2 3.9e-63 212.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EPE25784.1 - 1.1e-33 116.1 0.0 3.9e-33 114.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EPE25784.1 - 9.9e-24 84.2 11.4 2.7e-16 59.7 0.2 3.8 3 1 1 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EPE25784.1 - 7.4e-17 61.0 0.7 3.5e-16 58.8 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 PRP3 PF08572.5 EPE25785.1 - 4.2e-69 232.3 6.4 6.7e-69 231.6 4.5 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EPE25785.1 - 1.4e-40 137.9 1.5 3e-40 136.8 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF1227 PF06777.6 EPE25786.1 - 1.1e-57 193.7 0.2 3e-57 192.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EPE25786.1 - 2.7e-49 166.9 0.2 4.4e-49 166.2 0.2 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EPE25786.1 - 6.1e-44 149.9 0.0 2.1e-43 148.1 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 EPE25786.1 - 0.00059 19.3 0.0 0.1 12.0 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EPE25786.1 - 0.0016 17.2 0.1 0.016 14.0 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EPE25786.1 - 0.012 15.3 0.0 0.046 13.5 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EPE25786.1 - 0.033 13.4 0.0 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 EPE25786.1 - 0.043 13.9 0.1 3.1 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EPE25786.1 - 0.099 12.1 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain DSPc PF00782.15 EPE25787.1 - 3.7e-30 104.2 0.0 8.2e-24 83.6 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPE25787.1 - 1.1e-05 24.9 0.0 0.00023 20.6 0.0 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EPE25787.1 - 0.0085 16.1 0.1 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 Inositol hexakisphosphate Trypan_PARP PF05887.6 EPE25788.1 - 0.0038 17.0 2.6 0.0038 17.0 1.8 1.0 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.7 EPE25788.1 - 0.093 12.1 4.1 0.093 12.0 2.8 1.0 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF3886 PF13025.1 EPE25788.1 - 0.32 10.9 3.5 0.4 10.6 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DUF4632 PF15451.1 EPE25788.1 - 0.38 10.6 2.6 0.46 10.4 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF3154 PF11351.3 EPE25788.1 - 0.4 10.4 2.0 0.47 10.2 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) PepSY PF03413.14 EPE25788.1 - 0.67 10.6 5.6 0.78 10.4 3.9 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain NMT1 PF09084.6 EPE25789.1 - 6.9e-75 251.3 0.0 8.9e-75 250.9 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EPE25789.1 - 0.0001 21.7 0.3 0.21 10.9 0.1 2.9 2 1 0 3 3 3 2 NMT1-like family HIG_1_N PF04588.8 EPE25789.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Hypoxia induced protein conserved region Phosphonate-bd PF12974.2 EPE25789.1 - 0.082 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Histone PF00125.19 EPE25790.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EPE25790.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EPE25790.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPE25790.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPE25790.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EPE25790.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EPE25791.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EPE25791.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPE25791.1 - 0.0042 17.0 0.4 0.0073 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPE25791.1 - 0.039 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Fungal_trans PF04082.13 EPE25792.1 - 1.4e-22 79.8 1.2 2.2e-22 79.2 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CheC PF04509.7 EPE25792.1 - 0.057 13.1 0.1 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 CheC-like family zf-C2H2 PF00096.21 EPE25793.1 - 1.4e-09 37.7 14.8 0.00069 19.8 0.5 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE25793.1 - 1e-07 31.7 13.5 0.00067 19.8 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 EPE25793.1 - 0.00092 19.2 4.7 0.006 16.6 0.9 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EPE25793.1 - 0.28 11.4 4.9 34 4.9 0.5 3.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Glyco_hydro_76 PF03663.9 EPE25794.1 - 1.7e-127 425.8 18.6 2.2e-127 425.5 12.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EPE25794.1 - 0.0065 15.5 9.5 0.0089 15.1 0.2 3.0 2 1 1 3 3 3 1 Glycosyl Hydrolase Family 88 YmdB PF13277.1 EPE25794.1 - 0.055 12.4 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 YmdB-like protein p450 PF00067.17 EPE25795.1 - 2.6e-43 148.2 0.0 3.2e-23 81.9 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 Acetyltransf_7 PF13508.1 EPE25796.1 - 1.6e-07 31.3 0.0 2.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE25796.1 - 1.4e-06 28.2 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE25796.1 - 0.019 15.0 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NmrA PF05368.8 EPE25797.1 - 2.7e-26 92.2 3.7 6.6e-25 87.7 2.6 2.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE25797.1 - 1.6e-06 28.2 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Glyco_hydro_53 PF07745.8 EPE25797.1 - 0.00086 18.1 1.6 0.36 9.5 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 53 DUF4267 PF14087.1 EPE25798.1 - 4.2e-16 58.5 5.3 4.6e-16 58.3 3.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) TraW_N PF12477.3 EPE25798.1 - 0.098 12.6 1.2 0.24 11.3 0.9 1.7 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal zf-H2C2_2 PF13465.1 EPE25799.1 - 2.1e-10 40.3 15.7 9.9e-06 25.5 2.3 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EPE25799.1 - 2.9e-08 33.5 13.5 0.001 19.2 2.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE25799.1 - 7.5e-06 25.9 12.7 0.012 15.8 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Peptidase_M3 PF01432.15 EPE25800.1 - 1.9e-157 525.0 0.1 2.4e-157 524.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 EPE25800.1 - 0.0076 16.3 0.3 0.038 14.0 0.0 2.2 2 0 0 2 2 2 1 Effector protein EF-hand_7 PF13499.1 EPE25802.1 - 7.9e-13 48.3 0.6 2.4e-09 37.2 0.4 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPE25802.1 - 1.1e-09 37.3 0.6 0.0092 15.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EPE25802.1 - 1.2e-07 30.4 0.2 0.014 14.6 0.0 3.7 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 EPE25802.1 - 1.6e-06 27.9 0.0 0.069 13.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EPE25802.1 - 1.7e-05 24.3 0.2 0.00093 18.7 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain pair UPF0154 PF03672.8 EPE25802.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 EPE25802.1 - 4.5 6.7 5.4 2.3 7.7 0.7 2.6 2 0 0 2 2 2 0 EF hand Methyltransf_11 PF08241.7 EPE25803.1 - 4.2e-16 59.2 0.0 6.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE25803.1 - 4.2e-12 46.6 0.0 7.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE25803.1 - 1.2e-10 41.1 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE25803.1 - 2.3e-10 40.8 0.0 3.9e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE25803.1 - 2e-09 37.6 0.0 3.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE25803.1 - 2e-07 30.8 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE25803.1 - 5.3e-06 25.7 0.0 1.6e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 EPE25803.1 - 2e-05 23.5 0.0 3.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 EPE25803.1 - 0.001 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EPE25803.1 - 0.0066 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EPE25803.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EPE25803.1 - 0.032 12.9 0.0 0.047 12.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase CoA_binding_2 PF13380.1 EPE25804.1 - 2.6e-26 92.0 0.0 3.6e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Spore_coat_CotO PF14153.1 EPE25805.1 - 0.0012 18.3 0.5 0.0012 18.3 0.4 1.1 1 0 0 1 1 1 1 Spore coat protein CotO DUF883 PF05957.8 EPE25805.1 - 0.98 9.8 18.6 36 4.8 12.9 2.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) HAUS6_N PF14661.1 EPE25805.1 - 4.9 6.4 12.6 6.4 6.0 8.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Glyco_hydro_3 PF00933.16 EPE25806.1 - 1.2e-86 290.4 0.0 1.7e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE25806.1 - 1.4e-60 204.6 0.3 2.7e-60 203.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE25806.1 - 9.3e-25 86.3 0.1 2e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Sec62 PF03839.11 EPE25808.1 - 4.8e-51 173.3 0.1 4.8e-51 173.3 0.1 1.7 2 0 0 2 2 2 1 Translocation protein Sec62 DUF4414 PF14377.1 EPE25808.1 - 0.15 11.9 3.4 0.29 11.0 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) APC_CDC26 PF10471.4 EPE25808.1 - 0.2 12.4 8.5 0.76 10.5 2.2 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Lectin_C PF00059.16 EPE25809.1 - 0.0076 16.8 1.6 1.7 9.3 0.2 2.7 2 0 0 2 2 2 2 Lectin C-type domain RhoGAP PF00620.22 EPE25810.1 - 1.8e-44 150.9 2.0 2.2e-44 150.7 0.0 2.2 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.17 EPE25810.1 - 1.1e-13 51.0 16.9 7.6e-09 35.5 1.2 2.4 2 0 0 2 2 2 2 LIM domain zinc_ribbon_2 PF13240.1 EPE25810.1 - 0.032 13.7 3.3 0.72 9.4 0.0 3.8 3 1 0 3 3 3 0 zinc-ribbon domain DUF948 PF06103.6 EPE25810.1 - 0.21 11.4 3.9 0.64 9.9 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 EPE25810.1 - 0.6 10.5 10.3 0.035 14.4 1.2 3.1 2 1 0 2 2 2 0 SlyX Zn-ribbon_8 PF09723.5 EPE25810.1 - 3 7.8 18.9 0.51 10.3 1.0 4.2 4 0 0 4 4 4 0 Zinc ribbon domain Desulfoferrod_N PF06397.7 EPE25810.1 - 7.2 6.0 8.7 16 5.0 0.6 3.4 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain CLASP_N PF12348.3 EPE25811.1 - 6.8e-129 427.9 0.5 9.8e-90 299.8 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 EPE25811.1 - 6.8e-07 28.8 0.0 0.55 10.4 0.0 4.9 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 EPE25811.1 - 0.00047 20.3 1.6 0.31 11.3 0.0 4.8 4 1 1 5 5 5 2 HEAT repeats BSP PF04450.7 EPE25812.1 - 1.3e-73 246.8 0.0 1.6e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EPE25812.1 - 3.7e-07 30.2 0.2 2.4e-06 27.6 0.2 2.0 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EPE25812.1 - 0.00014 21.5 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 SprT-like family rRNA_processing PF08524.6 EPE25814.1 - 6.4e-07 29.2 21.8 2.2e-06 27.5 15.1 1.7 1 1 0 1 1 1 1 rRNA processing RR_TM4-6 PF06459.7 EPE25814.1 - 6.6 6.5 9.1 8.4 6.2 6.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4210 PF13915.1 EPE25815.1 - 3.7e-25 87.9 0.0 8.9e-25 86.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EPE25815.1 - 5.2e-20 71.0 0.5 1.5e-19 69.6 0.3 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis PPR_2 PF13041.1 EPE25816.1 - 2.9e-17 62.3 0.9 8.2e-05 22.5 0.0 7.3 6 2 2 8 8 8 4 PPR repeat family PPR_3 PF13812.1 EPE25816.1 - 1.4e-12 46.7 4.4 0.34 11.3 0.0 10.2 11 0 0 11 11 11 2 Pentatricopeptide repeat domain PPR PF01535.15 EPE25816.1 - 8e-08 31.7 2.3 2.7 8.1 0.0 8.0 9 0 0 9 9 9 2 PPR repeat PPR_1 PF12854.2 EPE25816.1 - 0.0043 16.4 0.0 41 3.7 0.0 4.8 5 0 0 5 5 5 0 PPR repeat TPR_14 PF13428.1 EPE25816.1 - 0.023 15.2 2.6 11 6.9 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3920 PF13058.1 EPE25816.1 - 0.057 13.2 0.0 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3920) Mo-co_dimer PF03404.11 EPE25818.1 - 2.5e-53 179.1 1.6 2.7e-53 179.0 0.3 1.7 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EPE25818.1 - 2.1e-49 167.1 0.0 3.4e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EPE25818.1 - 1.5e-30 105.1 0.0 2.7e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EPE25818.1 - 1.1e-24 86.0 0.0 4e-24 84.2 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 EPE25818.1 - 2.4e-23 82.7 0.0 1.2e-22 80.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EPE25818.1 - 0.0017 18.3 0.1 0.11 12.3 0.0 2.4 1 1 0 2 2 2 1 Ferric reductase NAD binding domain MIF4G PF02854.14 EPE25819.1 - 4.4e-61 205.9 0.1 6.7e-28 97.5 0.1 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EPE25819.1 - 1.2e-53 181.3 10.4 1.2e-53 181.3 7.2 2.5 3 0 0 3 3 3 1 Up-frameshift suppressor 2 Chitin_synth_2 PF03142.10 EPE25820.1 - 8.3e-24 83.8 3.4 1.5e-23 83.0 1.4 2.7 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EPE25820.1 - 9.8e-18 64.5 3.6 9.8e-18 64.5 2.5 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPE25820.1 - 2.9e-17 63.2 0.0 7.2e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EPE25820.1 - 0.0028 17.3 0.1 2.3 7.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Ribosomal_S19e PF01090.14 EPE25821.1 - 1.6e-56 189.6 0.2 1.8e-56 189.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Fmp27 PF10344.4 EPE25822.1 - 7.2e-235 781.7 0.0 1.3e-234 780.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EPE25822.1 - 4.6e-176 586.1 8.0 4.6e-176 586.1 5.6 2.8 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EPE25822.1 - 1.3e-155 518.4 4.1 1.3e-155 518.4 2.9 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EPE25822.1 - 8e-56 188.2 0.1 2.1e-55 186.9 0.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EPE25822.1 - 2.9e-55 186.3 0.1 6.7e-55 185.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EPE25822.1 - 3.1e-35 120.7 0.0 1.4e-34 118.6 0.0 2.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Stig1 PF04885.8 EPE25823.1 - 8.4e-06 26.0 22.5 8.4e-06 26.0 15.6 3.0 2 1 0 3 3 3 1 Stigma-specific protein, Stig1 Macoilin PF09726.4 EPE25823.1 - 4.3 5.4 6.5 5.1 5.2 4.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Zn_clus PF00172.13 EPE25824.1 - 1.9e-09 37.2 10.1 3.5e-09 36.4 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE25824.1 - 1.9e-06 26.7 0.0 2.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF521 PF04412.8 EPE25824.1 - 0.0012 17.5 0.0 0.0019 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) p450 PF00067.17 EPE25825.1 - 2e-76 257.3 0.0 7.1e-76 255.5 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 DUF1932 PF09130.6 EPE25826.1 - 1.6e-18 66.1 0.0 3.3e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 EPE25826.1 - 5.6e-07 29.8 0.1 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EPE25826.1 - 7.5e-07 29.1 0.1 1.5e-06 28.1 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EPE25826.1 - 0.0054 15.8 0.0 0.0089 15.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EPE25826.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RRM_1 PF00076.17 EPE25827.1 - 1.8e-18 65.9 0.0 2.7e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE25827.1 - 9.9e-13 47.8 0.0 1.5e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE25827.1 - 1.3e-06 28.1 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EPE25827.1 - 3.7e-06 27.2 13.8 3.7e-06 27.2 9.6 3.4 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 TPR_16 PF13432.1 EPE25828.1 - 2.8e-10 40.5 1.3 6.5e-05 23.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPE25828.1 - 1.3e-08 34.1 5.4 0.0021 17.8 0.1 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EPE25828.1 - 5.6e-08 32.8 0.0 2.3e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EPE25828.1 - 1.6e-07 31.1 3.2 0.23 11.4 0.1 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EPE25828.1 - 3.5e-06 26.5 2.4 0.011 15.3 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 EPE25828.1 - 8e-06 25.2 4.8 0.001 18.6 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPE25828.1 - 9.7e-06 25.8 9.5 0.0097 16.2 0.1 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPE25828.1 - 1.3e-05 25.4 4.0 0.18 12.5 0.1 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPE25828.1 - 4.4e-05 22.8 6.6 0.01 15.3 0.1 4.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPE25828.1 - 0.00016 21.4 4.6 4.3 7.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 EPE25828.1 - 0.00043 20.2 1.0 0.0022 17.9 0.7 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.9 EPE25828.1 - 0.00064 19.9 0.0 5.9 7.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.7 EPE25828.1 - 0.0013 19.2 7.0 2.3 8.9 0.0 5.1 5 1 0 5 5 4 1 Sel1 repeat TPR_17 PF13431.1 EPE25828.1 - 0.0016 18.4 1.6 0.78 10.0 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPE25828.1 - 0.0077 16.6 7.7 1.3 9.6 0.1 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc5 PF12862.2 EPE25828.1 - 0.013 15.3 0.3 0.43 10.4 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 DUF4194 PF13835.1 EPE25828.1 - 0.021 14.2 0.1 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) TPR_7 PF13176.1 EPE25828.1 - 0.058 13.2 3.4 0.42 10.5 0.1 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat ADH_zinc_N_2 PF13602.1 EPE25829.1 - 1.3e-15 58.4 0.0 3.1e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EPE25829.1 - 6.4e-12 45.1 0.0 1.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE25829.1 - 0.0022 17.7 0.1 0.052 13.3 0.0 2.7 1 1 2 3 3 3 1 Alcohol dehydrogenase GroES-like domain CBFD_NFYB_HMF PF00808.18 EPE25830.1 - 2.1e-15 56.4 0.8 3.6e-15 55.7 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPE25830.1 - 3.8e-06 26.9 0.2 7.1e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Acetyltransf_9 PF13527.1 EPE25831.1 - 5.8e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPE25831.1 - 0.00012 22.1 0.0 0.00031 20.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE25831.1 - 0.023 14.7 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family CAF-1_p150 PF11600.3 EPE25832.1 - 3.9 6.7 10.1 4.6 6.5 7.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Neisseria_TspB PF05616.8 EPE25832.1 - 5.6 5.2 7.4 6 5.1 5.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Peptidase_C15 PF01470.12 EPE25833.1 - 1.5e-17 64.1 0.0 1.8e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase Pkinase PF00069.20 EPE25834.1 - 7.6e-25 87.5 0.0 4.4e-24 85.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25834.1 - 1.5e-07 30.7 0.0 2.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPE25834.1 - 0.065 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AMP-binding PF00501.23 EPE25835.1 - 1.5e-63 214.6 0.0 2e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE25835.1 - 3.1e-06 28.0 0.0 6.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 EPE25836.1 - 2.5e-65 220.0 0.1 4.1e-65 219.3 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPE25836.1 - 1.5e-45 153.6 0.1 3.2e-45 152.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EPE25836.1 - 0.00046 20.1 0.2 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EPE25836.1 - 0.00047 19.7 0.4 0.028 14.0 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EPE25836.1 - 0.092 12.2 1.4 0.31 10.4 0.9 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EPE25837.1 - 6.5e-26 91.5 0.0 8.7e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE25837.1 - 2.2e-21 76.4 1.0 5.9e-21 75.1 0.7 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE25837.1 - 1.7e-10 40.8 1.6 5.3e-10 39.2 0.3 2.0 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EPE25837.1 - 0.063 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPE25837.1 - 0.09 11.4 0.1 0.23 10.1 0.1 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ketoacyl-synt PF00109.21 EPE25838.1 - 1.1e-72 244.5 0.9 1.7e-72 243.9 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPE25838.1 - 1.2e-54 185.7 0.0 1.9e-54 185.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EPE25838.1 - 2.7e-54 184.3 0.0 4.6e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EPE25838.1 - 6.7e-50 169.2 0.1 2.9e-49 167.1 0.0 2.1 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.17 EPE25838.1 - 7.5e-38 129.0 0.2 1.9e-37 127.7 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EPE25838.1 - 2.1e-37 128.6 0.7 1.2e-36 126.2 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EPE25838.1 - 7.5e-18 64.3 0.0 3.4e-17 62.1 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EPE25838.1 - 6.4e-07 29.5 0.2 1.7e-06 28.2 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EPE25838.1 - 4.1e-05 23.3 0.1 9.5e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.5 EPE25838.1 - 0.00027 20.5 0.4 0.0013 18.3 0.3 2.2 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EPE25838.1 - 0.0041 16.1 0.1 0.0078 15.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DNA_gyraseB_C PF00986.16 EPE25838.1 - 0.071 12.8 0.0 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus Fungal_trans PF04082.13 EPE25839.1 - 1.9e-07 30.2 0.8 3.4e-07 29.4 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE25839.1 - 1.9e-07 30.8 13.5 3.5e-07 30.0 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EPE25839.1 - 0.08 13.1 7.2 0.18 11.9 5.0 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DUF4646 PF15496.1 EPE25841.1 - 5.7e-05 23.1 0.1 0.00013 22.0 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) DUF331 PF03889.8 EPE25841.1 - 0.021 14.0 0.9 0.05 12.8 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function Zn_clus PF00172.13 EPE25842.1 - 7.7e-11 41.7 12.7 1.6e-10 40.7 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE25842.1 - 8.3e-07 27.9 0.1 2.3e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Velvet PF11754.3 EPE25843.1 - 8.9e-56 188.7 0.0 1.5e-55 187.9 0.0 1.3 1 0 0 1 1 1 1 Velvet factor DUF4611 PF15387.1 EPE25843.1 - 0.16 12.1 3.1 0.31 11.2 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EPE25843.1 - 0.19 11.2 1.9 0.3 10.5 1.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 EPE25843.1 - 7.8 6.8 14.0 0.52 10.6 4.6 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 EPE25844.1 - 2.6e-45 154.6 0.0 1.8e-44 151.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE25844.1 - 4.3e-33 114.4 0.0 6e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE25844.1 - 0.00035 19.6 0.0 0.0026 16.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPE25844.1 - 0.0011 18.0 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE25844.1 - 0.0026 17.5 0.2 0.17 11.5 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPE25844.1 - 0.35 9.6 0.0 0.55 8.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CTP_synth_N PF06418.9 EPE25845.1 - 5.7e-89 297.8 0.1 8e-89 297.3 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EPE25845.1 - 1.1e-55 188.0 0.0 1.7e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPE25845.1 - 3.8e-09 36.3 0.0 7.8e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 KRAB PF01352.22 EPE25845.1 - 0.026 13.9 0.7 0.071 12.5 0.5 1.7 1 0 0 1 1 1 0 KRAB box PI3_PI4_kinase PF00454.22 EPE25847.1 - 6.8e-31 107.5 0.0 1.1e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EPE25847.1 - 9.3e-20 70.1 0.1 2.2e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 EPE25847.1 - 0.0053 15.9 1.4 0.0097 15.1 1.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) LigB PF02900.13 EPE25848.1 - 0.054 12.4 0.1 0.1 11.5 0.1 1.4 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans PF04082.13 EPE25849.1 - 8.8e-12 44.4 8.2 1.6e-11 43.6 5.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE25849.1 - 1.4e-09 37.6 7.2 5.2e-09 35.8 5.0 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IF-2B PF01008.12 EPE25850.1 - 5e-76 255.3 3.6 5.2e-75 252.0 2.5 1.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family SMC_N PF02463.14 EPE25851.1 - 2.4e-66 223.1 6.4 5.5e-66 221.9 4.5 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPE25851.1 - 4.2e-28 97.7 0.1 3e-27 94.9 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPE25851.1 - 1.7e-14 54.4 3.3 2.5e-06 27.6 0.0 3.3 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EPE25851.1 - 7.1e-14 52.6 25.2 7.1e-14 52.6 17.5 7.7 3 2 2 5 5 5 1 AAA domain AAA_29 PF13555.1 EPE25851.1 - 0.00037 19.9 0.0 0.00091 18.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.6 EPE25851.1 - 0.0059 16.4 7.4 0.0059 16.4 5.1 8.0 2 2 6 8 8 8 1 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EPE25851.1 - 0.066 12.3 25.8 0.097 11.8 0.7 5.2 2 2 2 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EPE25851.1 - 0.16 10.3 0.0 0.16 10.3 0.0 6.1 3 2 2 6 6 6 0 AAA domain ABC_tran PF00005.22 EPE25851.1 - 0.26 11.5 0.0 0.26 11.5 0.0 5.9 3 2 0 3 3 3 0 ABC transporter Cupin_2 PF07883.6 EPE25852.1 - 5.5e-07 28.9 0.0 9.1e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EPE25852.1 - 0.016 14.8 0.0 0.029 13.9 0.0 1.4 1 1 0 1 1 1 0 Cupin Peptidase_S8 PF00082.17 EPE25853.1 - 1.2e-43 149.3 17.3 1.5e-43 149.0 12.0 1.2 1 0 0 1 1 1 1 Subtilase family Pribosyltran PF00156.22 EPE25854.1 - 1e-14 54.3 0.0 1.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 EPE25854.1 - 0.00073 18.8 0.0 0.0024 17.2 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase MFS_1 PF07690.11 EPE25855.1 - 2.3e-26 92.3 31.6 1.2e-25 89.9 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LAP1C PF05609.7 EPE25855.1 - 2.2 6.8 4.3 0.33 9.5 0.1 1.6 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Gamma-thionin PF00304.15 EPE25857.1 - 0.093 12.7 3.0 0.14 12.2 2.1 1.2 1 0 0 1 1 1 0 Gamma-thionin family DUF1996 PF09362.5 EPE25858.1 - 9.3e-87 290.5 1.0 1.1e-86 290.3 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Cu_amine_oxid PF01179.15 EPE25859.1 - 6e-162 539.0 0.1 7.1e-162 538.8 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EPE25859.1 - 1.7e-08 34.4 0.0 3.5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EPE25859.1 - 9.5e-07 28.8 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_2 PF13520.1 EPE25860.1 - 3.9e-62 210.1 39.7 4.9e-62 209.8 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE25860.1 - 2.4e-26 92.1 34.8 3.3e-26 91.6 24.1 1.1 1 0 0 1 1 1 1 Amino acid permease Amidohydro_2 PF04909.9 EPE25861.1 - 2e-43 148.9 0.0 3.1e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 EPE25861.1 - 2.3e-23 82.4 0.0 3.7e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE25861.1 - 0.17 11.8 3.5 0.32 10.9 2.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Polyketide_cyc2 PF10604.4 EPE25862.1 - 6.1e-09 36.1 0.0 6.9e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Cyclin_N PF00134.18 EPE25864.1 - 3.6e-07 29.7 0.1 1.2e-06 28.0 0.1 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3653 PF12375.3 EPE25864.1 - 0.1 12.8 0.1 0.39 10.9 0.1 2.0 1 0 0 1 1 1 0 Phage protein FAD_binding_4 PF01565.18 EPE25867.1 - 1.6e-16 60.0 0.2 4.1e-16 58.7 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE25867.1 - 5.5e-07 29.3 1.0 1.8e-06 27.7 0.7 1.9 1 0 0 1 1 1 1 Berberine and berberine like TyeA PF09059.5 EPE25867.1 - 0.029 14.3 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 TyeA Cytokin-bind PF09265.5 EPE25867.1 - 0.045 12.8 0.6 0.078 12.1 0.4 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding BNR PF02012.15 EPE25868.1 - 1.2e-08 33.4 25.0 0.18 11.7 0.1 7.7 7 0 0 7 7 7 5 BNR/Asp-box repeat CBM_1 PF00734.13 EPE25868.1 - 2.2e-08 33.5 7.3 5.9e-08 32.2 5.0 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Kelch_3 PF13415.1 EPE25868.1 - 1.7 8.9 8.4 9.5 6.5 0.0 3.8 3 0 0 3 3 3 0 Galactose oxidase, central domain DNA_pol_A_exo1 PF01612.15 EPE25870.1 - 0.0044 16.5 0.2 0.067 12.6 0.0 2.3 2 0 0 2 2 2 1 3'-5' exonuclease IL31 PF15209.1 EPE25870.1 - 0.044 13.3 0.2 0.12 11.9 0.1 1.7 1 1 1 2 2 2 0 Interleukin 31 AAA_10 PF12846.2 EPE25871.1 - 1.9e-10 40.6 0.0 1.3e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EPE25871.1 - 3.7e-05 23.2 0.0 0.00055 19.4 0.0 2.4 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF87 PF01935.12 EPE25871.1 - 0.0028 17.4 0.0 0.062 13.1 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EPE25871.1 - 0.032 14.3 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EPE25871.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EPE25871.1 - 0.077 12.4 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family TauD PF02668.11 EPE25872.1 - 4.9e-35 121.4 0.1 7.4e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EPE25872.1 - 7.3e-05 23.1 0.1 0.00023 21.4 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF971) IL17 PF06083.6 EPE25872.1 - 0.031 14.3 0.0 0.087 12.8 0.0 1.7 1 0 0 1 1 1 0 Interleukin-17 UQ_con PF00179.21 EPE25874.1 - 2.3e-41 140.5 0.0 3.9e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EPE25874.1 - 1.4e-06 27.7 0.3 2.9e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EPE25874.1 - 0.00048 19.8 0.0 0.00082 19.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPE25874.1 - 0.0049 16.7 0.0 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 RWD domain UEV PF05743.8 EPE25874.1 - 0.055 13.1 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 UEV domain AAA PF00004.24 EPE25875.1 - 1.1e-41 142.0 0.0 1.9e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE25875.1 - 5.9e-07 29.6 0.1 0.0002 21.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EPE25875.1 - 1.1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EPE25875.1 - 1.1e-05 24.4 0.0 1.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EPE25875.1 - 2.2e-05 24.2 0.1 7.1e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EPE25875.1 - 0.00029 19.9 0.0 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPE25875.1 - 0.00037 20.5 0.0 0.0013 18.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EPE25875.1 - 0.0013 18.6 0.6 0.0041 17.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPE25875.1 - 0.0022 17.9 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EPE25875.1 - 0.0032 17.1 0.1 0.34 10.5 0.1 2.6 1 1 1 2 2 2 1 NACHT domain AAA_17 PF13207.1 EPE25875.1 - 0.0043 17.8 0.2 0.013 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EPE25875.1 - 0.0054 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EPE25875.1 - 0.0064 16.2 0.3 0.015 14.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EPE25875.1 - 0.0076 16.1 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPE25875.1 - 0.0092 15.0 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EPE25875.1 - 0.01 16.1 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EPE25875.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EPE25875.1 - 0.024 13.3 0.6 0.046 12.4 0.1 1.7 2 1 0 2 2 2 0 TIP49 C-terminus NB-ARC PF00931.17 EPE25875.1 - 0.041 12.7 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EPE25875.1 - 0.043 14.0 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EPE25875.1 - 0.056 12.6 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EPE25875.1 - 0.058 12.4 0.2 0.48 9.4 0.1 2.1 1 1 0 2 2 2 0 KaiC AAA_24 PF13479.1 EPE25875.1 - 0.06 12.9 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EPE25875.1 - 0.061 12.5 0.3 0.21 10.7 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 EPE25875.1 - 0.12 11.3 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EPE25875.1 - 0.17 11.2 4.8 0.25 10.7 0.3 2.6 2 1 0 3 3 3 0 AAA domain Adap_comp_sub PF00928.16 EPE25878.1 - 3.1e-85 285.4 0.0 4e-85 285.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EPE25878.1 - 0.00012 21.8 0.2 0.00022 20.9 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 EPE25878.1 - 0.039 13.8 0.2 0.088 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) CoA_binding PF02629.14 EPE25879.1 - 5.6e-26 90.8 5.4 2.2e-25 89.0 1.3 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EPE25879.1 - 8.6e-25 87.1 0.3 1.4e-24 86.4 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EPE25879.1 - 3.9e-09 36.2 0.1 7.5e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EPE25879.1 - 0.00093 19.3 0.1 0.0028 17.7 0.1 1.9 1 0 0 1 1 1 1 CoA binding domain Radical_SAM PF04055.16 EPE25880.1 - 3.5e-15 56.5 0.1 1.2e-14 54.7 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EPE25880.1 - 5.6e-13 48.7 0.0 1.4e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE25880.1 - 0.0033 17.5 0.0 0.0072 16.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPE25880.1 - 0.1 12.7 0.0 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain HET PF06985.6 EPE25881.1 - 1.5e-18 67.2 0.6 3.5e-18 66.1 0.5 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CFEM PF05730.6 EPE25882.1 - 0.0076 16.0 4.1 0.0086 15.8 1.7 1.8 1 1 0 1 1 1 1 CFEM domain GFO_IDH_MocA PF01408.17 EPE25883.1 - 1.1e-21 77.5 0.1 2.2e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPE25883.1 - 6.4e-13 48.5 0.0 1.1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain OCD_Mu_crystall PF02423.10 EPE25883.1 - 0.0026 16.5 0.0 0.0056 15.4 0.0 1.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family DapB_N PF01113.15 EPE25883.1 - 0.013 15.4 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EPE25883.1 - 0.014 15.7 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 EPE25884.1 - 8.7e-20 71.5 0.0 1.4e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE25884.1 - 3.6e-10 39.7 0.2 2.1e-09 37.2 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE25884.1 - 0.0079 16.0 2.4 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EPE25884.1 - 0.018 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold BCNT PF07572.7 EPE25885.1 - 1.7e-23 82.3 1.2 1.7e-23 82.3 0.8 1.9 2 0 0 2 2 2 1 Bucentaur or craniofacial development Phage_B PF02304.10 EPE25886.1 - 7.6 6.8 15.6 0.095 12.9 0.4 4.4 4 1 1 5 5 5 0 Scaffold protein B Dus PF01207.12 EPE25887.1 - 6.3e-59 199.3 0.0 4.2e-58 196.6 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EPE25887.1 - 0.0073 15.3 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Imm20 PF15568.1 EPE25887.1 - 0.025 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 20 MIP-T3 PF10243.4 EPE25892.1 - 0.044 12.2 64.1 0.092 11.1 44.4 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF572 PF04502.8 EPE25892.1 - 1.6 7.8 41.2 3.1 6.9 28.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pectate_lyase_3 PF12708.2 EPE25894.1 - 1.1e-84 284.0 36.3 4.4e-72 242.8 9.0 3.6 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EPE25894.1 - 5.3e-06 25.8 1.8 0.02 14.3 0.0 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase EB1 PF03271.12 EPE25895.1 - 7.1e-17 61.1 0.9 1.5e-16 60.1 0.6 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EPE25895.1 - 7.5e-08 32.3 0.8 1.4e-07 31.5 0.5 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Syja_N PF02383.13 EPE25895.1 - 0.029 13.1 0.0 0.033 12.9 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain Phi-29_GP3 PF05435.6 EPE25895.1 - 0.094 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 Suppressor_APC PF11414.3 EPE25895.1 - 0.13 12.0 0.9 0.27 11.0 0.6 1.6 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein PX PF00787.19 EPE25896.1 - 1.3e-14 53.9 0.0 2.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EPE25896.1 - 1.5e-10 40.6 8.7 2.9e-10 39.6 6.0 1.5 1 0 0 1 1 1 1 SNARE domain Crystall_3 PF08964.5 EPE25897.1 - 0.11 12.2 0.1 1.4 8.6 0.0 1.9 1 1 1 2 2 2 0 Beta/Gamma crystallin NAD_binding_10 PF13460.1 EPE25898.1 - 8.7e-18 64.9 0.0 7e-17 62.0 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE25898.1 - 1.5e-11 44.2 0.0 1.1e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPE25898.1 - 5.9e-07 28.9 0.0 1.5e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EPE25898.1 - 8.5e-06 25.7 0.1 1.5e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EPE25898.1 - 0.00016 20.6 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EPE25898.1 - 0.00019 20.2 0.0 0.00025 19.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EPE25898.1 - 0.0052 16.7 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 EPE25898.1 - 0.0072 16.0 0.1 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPE25898.1 - 0.02 13.7 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EPE25898.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EPE25898.1 - 0.023 13.6 0.0 0.049 12.5 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.19 EPE25898.1 - 0.097 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 EPE25899.1 - 4e-28 98.1 55.9 9.3e-28 96.9 36.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE25899.1 - 1e-11 44.0 13.3 1e-11 44.0 9.2 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter ADH_N PF08240.7 EPE25900.1 - 5.1e-26 90.5 3.3 8.1e-26 89.9 2.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE25900.1 - 4e-14 52.2 0.0 6.9e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPE25900.1 - 0.00013 21.2 0.2 0.00023 20.3 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fer4_4 PF12800.2 EPE25900.1 - 9.2 6.9 7.4 6.1 7.4 1.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain zf-HC5HC2H_2 PF13832.1 EPE25901.1 - 7.2e-33 112.8 6.8 7.2e-33 112.8 4.7 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EPE25901.1 - 2.6e-26 91.5 6.6 2.6e-26 91.5 4.6 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain EPL1 PF10513.4 EPE25901.1 - 1.7e-22 80.3 0.0 1.2e-21 77.6 0.0 2.5 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 EPE25901.1 - 2.2e-14 52.4 1.7 2.2e-14 52.4 1.2 1.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EPE25901.1 - 2.4e-08 33.5 22.8 1.5e-07 30.9 6.5 2.7 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 EPE25901.1 - 0.32 10.7 14.2 0.15 11.8 1.1 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 EPE25901.1 - 2.4 8.2 21.7 0.038 13.9 3.4 2.7 2 0 0 2 2 2 0 RING-like domain WD40 PF00400.27 EPE25903.1 - 2e-44 147.9 16.1 1.1e-09 37.8 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EPE25903.1 - 9.1e-09 34.9 0.6 2.2e-08 33.6 0.4 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EPE25903.1 - 7.8e-07 27.5 0.2 0.0042 15.3 0.0 3.5 1 1 1 3 3 3 3 Nucleoporin Nup120/160 F-box PF00646.28 EPE25903.1 - 2.1e-06 27.2 0.1 4.2e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EPE25903.1 - 0.006 16.0 0.0 0.057 12.8 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 EPE25903.1 - 0.021 13.6 0.4 12 4.4 0.0 3.2 2 1 0 3 3 3 0 Nup133 N terminal like DUF1900 PF08954.6 EPE25903.1 - 0.082 12.4 0.4 1 8.8 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1900) Ribosomal_S7e PF01251.13 EPE25904.1 - 7.2e-83 276.7 0.2 8e-83 276.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.8 EPE25905.1 - 1.8e-167 558.0 0.0 2.3e-167 557.6 0.0 1.1 1 0 0 1 1 1 1 Dynactin p62 family Glyco_hydro_cc PF11790.3 EPE25906.1 - 2.9e-60 203.6 6.7 3.3e-60 203.4 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SMC_N PF02463.14 EPE25908.1 - 4.6e-51 173.1 26.0 1.6e-49 168.1 18.1 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPE25908.1 - 3.9e-26 91.3 0.0 1.5e-25 89.4 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EPE25908.1 - 1.1e-13 51.9 7.6 1.1e-13 51.9 5.3 6.5 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.1 EPE25908.1 - 3.8e-09 36.9 12.6 0.00015 21.8 0.1 4.0 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EPE25908.1 - 2.4e-08 33.3 0.0 5.4e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EPE25908.1 - 5.3e-08 32.4 21.6 0.00091 18.5 3.0 5.2 5 0 0 5 5 5 4 Reovirus sigma C capsid protein Tropomyosin PF00261.15 EPE25908.1 - 0.00028 20.0 40.5 0.00028 20.0 28.1 5.6 4 1 1 5 5 5 4 Tropomyosin Spc7 PF08317.6 EPE25908.1 - 0.0013 17.4 12.5 0.0013 17.4 8.7 6.6 3 2 4 7 7 7 4 Spc7 kinetochore protein SbcCD_C PF13558.1 EPE25908.1 - 0.0042 16.9 0.0 0.019 14.8 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Tropomyosin_1 PF12718.2 EPE25908.1 - 0.0048 16.7 18.5 0.0048 16.7 12.8 7.3 4 2 2 7 7 6 1 Tropomyosin like AAA_13 PF13166.1 EPE25908.1 - 0.036 12.5 108.0 0.035 12.5 12.6 6.4 4 2 2 6 6 6 0 AAA domain DUF2838 PF10998.3 EPE25909.1 - 3.7e-46 155.5 11.3 3.7e-46 155.5 7.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) AAA_27 PF13514.1 EPE25909.1 - 0.023 12.4 2.1 0.033 11.8 1.4 1.1 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 EPE25909.1 - 0.95 8.3 2.8 1.9 7.3 2.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Not3 PF04065.10 EPE25909.1 - 0.96 8.6 5.8 0.75 9.0 1.9 1.9 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component WD40 PF00400.27 EPE25910.1 - 2.6e-31 106.3 10.2 1.5e-05 24.6 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EPE25910.1 - 5.6e-07 29.4 0.0 0.024 14.3 0.0 3.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF3425 PF11905.3 EPE25910.1 - 0.066 13.1 0.2 0.6 10.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3425) Glyco_hydro_32N PF00251.15 EPE25911.1 - 2.3e-82 276.7 5.4 3.1e-82 276.4 3.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EPE25911.1 - 0.087 13.2 0.1 0.22 11.8 0.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal Peptidase_M20 PF01546.23 EPE25912.1 - 1.2e-17 64.0 0.0 1.7e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPE25912.1 - 1.1e-09 38.0 0.0 2.4e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain CorA PF01544.13 EPE25913.1 - 0.0094 15.0 3.5 0.011 14.7 1.7 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein p450 PF00067.17 EPE25914.1 - 1.4e-30 106.2 0.0 3.6e-27 94.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 ABC2_membrane PF01061.19 EPE25915.1 - 6.8e-85 283.5 46.5 3.7e-44 150.4 16.2 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPE25915.1 - 1.2e-37 129.2 0.0 5.3e-18 65.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EPE25915.1 - 2.3e-36 123.5 2.7 9.4e-31 105.5 0.0 3.2 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EPE25915.1 - 5.4e-16 58.4 0.0 1.2e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EPE25915.1 - 8.5e-08 31.8 0.0 0.0003 20.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPE25915.1 - 8.6e-06 25.1 1.2 0.0034 16.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EPE25915.1 - 3.8e-05 22.9 0.0 0.0011 18.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EPE25915.1 - 5.1e-05 23.3 0.3 0.078 12.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPE25915.1 - 5.4e-05 23.2 1.6 0.0058 16.6 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EPE25915.1 - 6.4e-05 22.2 0.0 0.7 9.0 0.0 3.5 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EPE25915.1 - 0.0013 18.8 0.6 0.06 13.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPE25915.1 - 0.0037 17.1 0.1 0.097 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EPE25915.1 - 0.016 14.8 0.1 6.8 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EPE25915.1 - 0.02 15.1 0.0 0.76 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EPE25915.1 - 0.026 15.3 0.0 0.4 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EPE25915.1 - 0.034 14.4 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPE25915.1 - 0.036 13.8 2.4 1.2 8.8 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 EPE25915.1 - 0.057 13.6 0.0 17 5.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EPE25915.1 - 0.066 13.1 0.7 0.12 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EPE25915.1 - 0.071 12.7 0.9 2.9 7.5 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EPE25915.1 - 0.12 12.0 0.0 7.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 EPE25915.1 - 0.15 11.4 1.3 10 5.4 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 EPE25915.1 - 0.17 11.8 0.6 1.5 8.8 0.0 2.6 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 EPE25915.1 - 0.17 11.3 0.3 2.4 7.6 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EPE25915.1 - 0.25 11.3 0.0 32 4.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.1 EPE25915.1 - 0.3 10.0 0.0 0.87 8.5 0.0 1.6 1 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 EPE25915.1 - 0.42 10.1 0.3 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EPE25915.1 - 0.44 9.9 3.9 0.5 9.8 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 EPE25915.1 - 0.49 9.3 49.1 0.3 10.0 11.8 3.1 2 1 1 3 3 3 0 ABC-2 family transporter protein Lactamase_B_2 PF12706.2 EPE25916.1 - 3.7e-28 98.4 0.0 5.6e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPE25916.1 - 1.1e-08 34.9 0.0 2.6e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPE25916.1 - 0.0057 16.3 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily EthD PF07110.6 EPE25917.1 - 1.7e-16 60.9 0.0 2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 EthD domain ORC2 PF04084.9 EPE25920.1 - 0.028 13.2 0.8 0.92 8.2 0.1 2.4 2 0 0 2 2 2 0 Origin recognition complex subunit 2 NACHT PF05729.7 EPE25921.1 - 5e-13 49.0 0.0 1.2e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain zf-C2H2_4 PF13894.1 EPE25921.1 - 0.00022 21.2 28.3 0.0049 17.1 0.6 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger AAA_22 PF13401.1 EPE25921.1 - 0.00044 20.4 0.1 0.0025 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain zf-C2H2 PF00096.21 EPE25921.1 - 0.00045 20.3 1.7 0.00045 20.3 1.2 5.6 5 1 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EPE25921.1 - 0.0021 18.1 7.0 0.75 10.0 0.2 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding AAA PF00004.24 EPE25921.1 - 0.0065 16.6 0.9 0.088 13.0 0.6 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EPE25921.1 - 0.034 13.8 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain zf-C2H2_6 PF13912.1 EPE25921.1 - 0.079 12.8 5.2 0.44 10.5 0.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE25921.1 - 6.5 7.2 25.7 0.29 11.4 0.3 4.6 4 0 0 4 4 4 0 Zinc-finger double domain SNF2_N PF00176.18 EPE25922.1 - 9.2e-69 231.5 0.1 1.3e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE25922.1 - 5e-09 35.8 0.0 1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPE25922.1 - 1.8e-06 27.5 0.0 4.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPE25922.1 - 2.5e-06 27.4 0.0 7.2e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 EPE25922.1 - 0.0021 17.7 8.5 0.0045 16.6 5.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE25922.1 - 0.18 11.4 8.6 0.45 10.2 5.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EPE25922.1 - 1.1 9.1 6.8 2.8 7.9 4.7 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4_2 PF13923.1 EPE25922.1 - 1.9 8.5 7.5 7 6.7 5.2 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PTPA PF03095.10 EPE25923.1 - 1.2e-111 372.6 0.0 1.5e-111 372.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNase_PH PF01138.16 EPE25924.1 - 4.3e-12 46.4 0.2 6.6e-12 45.8 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_kinase PF01513.16 EPE25925.1 - 1.2e-68 230.9 0.0 1.7e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase PAN_1 PF00024.21 EPE25926.1 - 0.028 14.1 0.9 0.066 12.9 0.0 2.1 2 0 0 2 2 2 0 PAN domain Anp1 PF03452.9 EPE25928.1 - 1.5e-110 368.5 0.0 2e-110 368.2 0.0 1.0 1 0 0 1 1 1 1 Anp1 ODV-E18 PF10717.4 EPE25928.1 - 0.014 14.7 0.0 0.036 13.4 0.0 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Glycos_transf_2 PF00535.21 EPE25928.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 UQ_con PF00179.21 EPE25931.1 - 9.9e-25 86.6 0.0 1.2e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPE25931.1 - 0.086 12.7 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain NUP PF06516.6 EPE25932.1 - 1.1e-112 375.9 0.0 1.4e-112 375.6 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Collagen PF01391.13 EPE25933.1 - 5.9e-20 70.5 88.3 6.6e-08 31.9 17.6 3.5 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) WSC PF01822.14 EPE25933.1 - 3.1e-12 46.2 9.4 5.8e-12 45.3 6.5 1.5 1 0 0 1 1 1 1 WSC domain CBM_4_9 PF02018.12 EPE25933.1 - 0.0098 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain WSC PF01822.14 EPE25934.1 - 2.2e-17 62.7 8.3 3.2e-17 62.2 5.7 1.2 1 0 0 1 1 1 1 WSC domain Collagen PF01391.13 EPE25934.1 - 5.3e-07 29.0 26.3 1e-06 28.2 18.2 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF2841 PF11001.3 EPE25935.1 - 1.4e-41 141.2 1.4 2.4e-41 140.5 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ABC_membrane PF00664.18 EPE25936.1 - 2.2e-63 214.2 28.2 3e-34 118.7 6.6 3.8 3 1 1 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.22 EPE25936.1 - 1.2e-49 168.1 0.7 2.5e-30 105.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EPE25936.1 - 1.3e-09 37.6 2.1 0.0069 15.6 0.1 4.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EPE25936.1 - 4.7e-05 23.4 0.8 0.2 11.6 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EPE25936.1 - 4.9e-05 23.4 0.1 2.4 8.0 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 EPE25936.1 - 7.2e-05 22.2 0.0 0.26 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EPE25936.1 - 0.00012 21.9 0.2 0.75 9.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EPE25936.1 - 0.00026 20.2 0.0 0.069 12.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EPE25936.1 - 0.00034 20.4 0.2 0.042 13.6 0.0 2.6 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 EPE25936.1 - 0.00037 20.9 0.1 1.4 9.4 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 EPE25936.1 - 0.0012 18.5 1.5 0.32 10.5 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EPE25936.1 - 0.0014 18.9 1.0 0.12 12.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EPE25936.1 - 0.0015 18.0 0.5 3.1 7.3 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EPE25936.1 - 0.0023 17.4 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.12 EPE25936.1 - 0.003 17.4 0.1 0.85 9.3 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 CDC45 PF02724.9 EPE25936.1 - 0.017 13.2 0.1 0.026 12.5 0.1 1.2 1 0 0 1 1 1 0 CDC45-like protein CAF-1_p150 PF11600.3 EPE25936.1 - 0.12 11.7 11.1 0.19 11.1 7.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_17 PF13207.1 EPE25936.1 - 0.14 12.9 0.0 21 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EPE25936.1 - 0.43 10.2 2.1 1.1 8.9 0.0 2.5 3 0 0 3 3 3 0 NACHT domain HLH PF00010.21 EPE25937.1 - 1.9e-12 46.6 0.2 4.1e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SRP_SPB PF02978.14 EPE25937.1 - 0.012 15.8 0.9 0.048 13.9 0.3 2.3 2 1 0 2 2 2 0 Signal peptide binding domain CLTH PF10607.4 EPE25938.1 - 9.3e-33 112.9 0.1 1.7e-32 112.1 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EPE25938.1 - 0.0012 18.4 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 LisH Nic96 PF04097.9 EPE25938.1 - 0.0024 16.0 0.4 0.013 13.6 0.0 1.9 2 0 0 2 2 2 1 Nup93/Nic96 DUF4206 PF13901.1 EPE25938.1 - 0.086 12.3 3.2 0.44 10.0 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) Peptidase_M28 PF04389.12 EPE25941.1 - 1.7e-32 112.5 0.0 3.5e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EPE25941.1 - 2.1e-05 24.1 0.0 4.6e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Acetyltransf_1 PF00583.19 EPE25942.1 - 2.7e-11 43.3 0.0 4.9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE25942.1 - 1.8e-08 34.4 0.0 7.5e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE25942.1 - 0.0017 18.4 0.0 0.011 15.9 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE25942.1 - 0.0063 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE25942.1 - 0.0089 15.7 0.0 0.021 14.5 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein AMP-binding PF00501.23 EPE25943.1 - 1.5e-73 247.5 0.3 5.5e-73 245.7 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.15 EPE25943.1 - 8.7e-59 198.8 0.0 1.1e-33 116.4 0.0 2.6 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.20 EPE25943.1 - 1.4e-27 95.7 0.2 7.7e-13 48.5 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Peptidase_S58 PF03576.9 EPE25943.1 - 0.035 13.2 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S58 IncA PF04156.9 EPE25944.1 - 0.037 13.6 10.9 0.083 12.4 7.5 1.5 1 0 0 1 1 1 0 IncA protein AAA_35 PF14516.1 EPE25944.1 - 0.2 10.2 2.6 0.31 9.6 1.8 1.2 1 0 0 1 1 1 0 AAA-like domain Herpes_UL25 PF01499.11 EPE25944.1 - 0.59 8.3 4.4 0.94 7.7 3.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Spc7 PF08317.6 EPE25944.1 - 0.61 8.6 10.9 1.1 7.8 7.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4239 PF14023.1 EPE25944.1 - 0.65 9.3 1.6 1.1 8.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) CP12 PF02672.10 EPE25944.1 - 1.3 9.5 6.1 12 6.4 2.3 2.7 2 0 0 2 2 2 0 CP12 domain NmrA PF05368.8 EPE25945.1 - 7.2e-44 149.7 0.0 8.6e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE25945.1 - 1.1e-12 48.3 0.0 1.4e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE25945.1 - 0.00014 20.6 0.0 0.00019 20.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE25945.1 - 0.0019 17.7 0.1 0.0024 17.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EPE25945.1 - 0.0046 16.8 0.5 0.0071 16.2 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EPE25945.1 - 0.035 14.1 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 EPE25945.1 - 0.036 14.1 0.1 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SGT1 PF07093.6 EPE25945.1 - 0.22 9.8 0.0 0.29 9.4 0.0 1.1 1 0 0 1 1 1 0 SGT1 protein Fungal_trans PF04082.13 EPE25946.1 - 8.7e-20 70.6 0.1 1.4e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE25946.1 - 5.7e-08 32.5 11.6 1.1e-07 31.6 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ytp1 PF10355.4 EPE25947.1 - 1.2e-87 293.6 14.3 1.2e-87 293.6 9.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EPE25947.1 - 4e-32 109.9 4.1 4e-32 109.9 2.8 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF3671 PF12420.3 EPE25947.1 - 9.6 6.2 10.6 2.2 8.2 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function Ank_2 PF12796.2 EPE25948.1 - 2.6e-49 165.4 0.0 1.7e-15 57.1 0.1 9.7 7 3 0 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EPE25948.1 - 4.3e-43 143.0 3.0 1.9e-07 30.5 0.1 11.3 13 0 0 13 13 13 7 Ankyrin repeat Ank_3 PF13606.1 EPE25948.1 - 1.6e-34 114.4 1.7 3.1e-05 23.7 0.1 12.4 14 0 0 14 14 14 6 Ankyrin repeat Ank_4 PF13637.1 EPE25948.1 - 7e-33 112.4 0.1 2e-06 28.1 0.0 9.8 8 1 1 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE25948.1 - 4e-28 96.8 1.8 8e-05 22.7 0.0 9.2 8 1 1 9 9 9 5 Ankyrin repeats (many copies) ABM PF03992.11 EPE25949.1 - 0.0026 17.7 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF605 PF04652.11 EPE25951.1 - 1.2 8.4 19.9 1.5 8.1 13.8 1.2 1 0 0 1 1 1 0 Vta1 like Whi5 PF08528.6 EPE25952.1 - 2.3e-10 39.7 0.0 4.3e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Whi5 like V-SNARE_C PF12352.3 EPE25955.1 - 3.7e-13 49.3 1.2 5.9e-13 48.6 0.1 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EPE25955.1 - 8.5e-05 22.1 0.4 0.0021 17.7 0.0 2.4 2 1 0 2 2 2 1 Sec20 V-SNARE PF05008.10 EPE25955.1 - 0.023 14.8 0.4 0.068 13.3 0.1 1.9 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus HR1 PF02185.11 EPE25955.1 - 0.025 14.2 0.5 0.025 14.2 0.3 1.7 2 0 0 2 2 2 0 Hr1 repeat AAA_11 PF13086.1 EPE25955.1 - 0.049 13.1 0.3 0.18 11.3 0.2 1.7 2 0 0 2 2 2 0 AAA domain Cytochrom_B562 PF07361.6 EPE25955.1 - 0.059 13.7 0.3 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 Cytochrome b562 DUF3154 PF11351.3 EPE25955.1 - 0.092 12.5 0.3 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) DHC_N1 PF08385.7 EPE25955.1 - 0.11 10.8 0.4 0.17 10.1 0.1 1.4 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 T2SM PF04612.7 EPE25955.1 - 0.92 9.2 3.1 5.4 6.7 0.4 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Arb1 PF09692.5 EPE25956.1 - 5.6e-104 348.1 0.2 3e-103 345.7 0.2 1.9 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF188 PF02639.9 EPE25956.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 IPK PF03770.11 EPE25957.1 - 1.1e-50 172.0 0.0 1.4e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Clp1 PF06807.9 EPE25958.1 - 1.1e-26 93.8 0.0 1.7e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EPE25958.1 - 1.9e-08 34.1 0.0 3.9e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EPE25958.1 - 5.1e-06 26.4 0.0 2.9e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EPE25958.1 - 6e-05 22.5 0.0 0.066 12.6 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 EPE25958.1 - 0.002 17.5 0.0 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Dynamin_N PF00350.18 EPE25958.1 - 0.0044 16.8 0.0 1.3 8.8 0.0 2.4 2 1 0 2 2 2 1 Dynamin family AAA_21 PF13304.1 EPE25958.1 - 0.0062 16.5 0.0 0.0093 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EPE25958.1 - 0.0071 15.9 0.0 0.063 12.8 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EPE25958.1 - 0.0084 16.4 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 EPE25958.1 - 0.024 14.0 0.1 0.054 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EPE25958.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EPE25958.1 - 0.048 12.7 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_35 PF14516.1 EPE25958.1 - 0.049 12.2 0.0 0.074 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Miro PF08477.8 EPE25958.1 - 0.052 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 EPE25958.1 - 0.12 11.6 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 EPE25958.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EPE25958.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE25958.1 - 0.15 12.9 0.0 0.36 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EPE25958.1 - 0.18 10.9 0.0 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MMS1_N PF10433.4 EPE25960.1 - 6.8e-77 258.7 0.0 1.8e-76 257.3 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EPE25960.1 - 7.9e-61 205.9 0.1 6.3e-60 202.9 0.0 2.4 3 0 0 3 3 3 1 CPSF A subunit region PQQ_2 PF13360.1 EPE25960.1 - 0.0091 15.4 0.1 11 5.4 0.0 3.3 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 EPE25960.1 - 0.024 14.8 1.9 15 6.0 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain Sin_N PF04801.8 EPE25961.1 - 9.3e-21 74.1 7.9 1.6e-20 73.3 3.6 2.3 1 1 1 2 2 2 1 Sin-like protein conserved region Pmp3 PF01679.12 EPE25962.1 - 7.2e-20 70.4 4.9 9.3e-20 70.0 3.4 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NAD_binding_2 PF03446.10 EPE25963.1 - 3.1e-38 131.1 0.1 4.5e-38 130.6 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EPE25963.1 - 2.9e-29 101.6 0.0 6e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 EPE25963.1 - 4.3e-07 28.9 0.0 9.8e-07 27.8 0.0 1.5 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EPE25963.1 - 8.6e-06 26.0 0.0 1.9e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EPE25963.1 - 0.0026 18.2 0.0 0.007 16.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RestrictionMunI PF11407.3 EPE25963.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme MunI ATP-synt_C PF00137.16 EPE25964.1 - 3e-29 100.7 26.6 3.1e-18 65.4 5.0 2.4 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 EPE25964.1 - 0.21 11.2 3.7 1.3 8.7 2.3 2.4 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Cation_efflux PF01545.16 EPE25964.1 - 6.3 5.7 9.8 0.2 10.6 0.7 2.3 1 1 0 2 2 2 0 Cation efflux family TFIIA_gamma_N PF02268.11 EPE25965.1 - 5.2e-27 93.1 0.3 7.3e-27 92.6 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EPE25965.1 - 6.1e-26 89.9 1.0 8.3e-26 89.5 0.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit EamA PF00892.15 EPE25966.1 - 0.00012 22.0 15.4 0.00025 21.0 10.7 1.5 1 1 0 1 1 1 1 EamA-like transporter family UPF0546 PF10639.4 EPE25966.1 - 0.22 11.3 4.7 0.33 10.7 3.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0546 EmrE PF13536.1 EPE25966.1 - 0.25 11.5 12.1 0.12 12.5 6.3 1.8 1 1 1 2 2 2 0 Multidrug resistance efflux transporter KilA-N PF04383.8 EPE25968.1 - 0.00093 18.7 0.2 0.006 16.1 0.0 2.3 2 1 0 2 2 2 1 KilA-N domain SMAP PF15477.1 EPE25969.1 - 0.35 11.1 1.8 0.99 9.7 1.2 1.7 1 0 0 1 1 1 0 Small acidic protein family Alk_phosphatase PF00245.15 EPE25972.1 - 3.1e-111 372.0 0.0 3.9e-111 371.7 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EPE25972.1 - 0.00082 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 EPE25972.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Ribosomal_L34e PF01199.13 EPE25973.1 - 5.5e-37 125.8 2.6 7.7e-37 125.4 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Gaa1 PF04114.9 EPE25974.1 - 2.2e-99 333.4 3.5 3.2e-99 332.9 2.4 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 EPE25975.1 - 4.9e-14 52.5 8.1 4.9e-14 52.5 5.6 1.7 2 0 0 2 2 2 1 Rhomboid family 5TM-5TMR_LYT PF07694.7 EPE25975.1 - 0.14 11.4 4.3 0.057 12.7 1.1 1.7 2 0 0 2 2 2 0 5TMR of 5TMR-LYT Aconitase PF00330.15 EPE25976.1 - 3.7e-168 559.7 0.0 6.4e-168 559.0 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPE25976.1 - 1.3e-46 157.9 0.0 2.4e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 EPE25977.1 - 4.9e-09 36.0 5.8 2.8e-08 33.6 0.8 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding L31 PF09784.4 EPE25977.1 - 0.11 12.5 2.4 0.15 12.0 1.2 1.6 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 zf-H2C2_2 PF13465.1 EPE25977.1 - 0.12 12.7 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 EPE25977.1 - 0.14 12.0 0.2 0.14 12.0 0.2 2.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 EPE25977.1 - 0.27 11.5 4.8 1.3 9.2 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EPE25977.1 - 3 8.3 7.3 0.99 9.8 0.5 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger DASH_Dam1 PF08653.5 EPE25978.1 - 1.8e-28 98.0 2.0 2.4e-28 97.6 1.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.15 EPE25979.1 - 7.1e-45 152.3 0.0 1.4e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPE25979.1 - 2.8e-16 59.3 0.0 7.2e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPE25979.1 - 2.1e-09 37.4 0.0 4.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF4463 PF14703.1 EPE25979.1 - 0.024 15.1 0.9 0.15 12.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Ion_trans_N PF08412.5 EPE25979.1 - 0.14 11.5 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal HIT PF01230.18 EPE25980.1 - 1.1e-24 86.7 0.3 1.7e-24 86.2 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPE25980.1 - 1.1e-15 57.9 0.5 1.3e-15 57.5 0.1 1.3 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EPE25980.1 - 4.2e-07 29.6 0.5 5.9e-07 29.1 0.3 1.3 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Ssl1 PF04056.9 EPE25980.1 - 0.064 12.8 0.0 0.089 12.3 0.0 1.1 1 0 0 1 1 1 0 Ssl1-like Mog1 PF04603.7 EPE25981.1 - 3e-18 66.1 0.0 4.5e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Myb_DNA-bind_6 PF13921.1 EPE25982.1 - 6.8e-14 51.7 0.5 1e-10 41.5 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPE25982.1 - 1.3e-10 41.1 1.0 3.9e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 EPE25982.1 - 0.027 13.9 0.0 0.071 12.5 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 PROCN PF08083.6 EPE25983.1 - 6.8e-223 739.5 7.2 6.8e-223 739.5 5.0 1.6 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EPE25983.1 - 2.5e-125 416.3 1.7 5.1e-125 415.3 1.2 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EPE25983.1 - 1e-94 314.2 1.2 2.2e-94 313.1 0.8 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EPE25983.1 - 5.1e-78 259.9 2.5 9.4e-78 259.1 1.0 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EPE25983.1 - 1.5e-65 218.8 0.1 3.2e-65 217.8 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EPE25983.1 - 2.8e-45 153.0 0.2 1.1e-44 151.1 0.0 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 EPE25983.1 - 7.8e-45 150.6 0.2 2.1e-44 149.2 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 OCD_Mu_crystall PF02423.10 EPE25983.1 - 0.13 10.9 1.4 0.24 10.1 0.9 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Lactamase_B PF00753.22 EPE25984.1 - 9.8e-24 84.0 0.8 1.3e-23 83.6 0.6 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPE25984.1 - 0.0019 17.7 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ytp1 PF10355.4 EPE25985.1 - 1.5e-106 355.5 12.6 2.8e-106 354.6 8.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EPE25985.1 - 7.5e-32 109.0 6.7 7.5e-32 109.0 4.7 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) CRISPR_Cse2 PF09485.5 EPE25985.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) NADH-u_ox-rdase PF10785.4 EPE25985.1 - 0.34 11.1 6.9 4.2 7.6 0.1 4.0 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit COX5B PF01215.14 EPE25986.1 - 1.7e-35 121.6 0.0 3.4e-35 120.6 0.0 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EPE25986.1 - 0.01 15.2 1.0 2.8 7.5 0.1 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger ABC_tran PF00005.22 EPE25987.1 - 3.1e-33 114.9 0.0 7.2e-33 113.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EPE25987.1 - 2.4e-30 105.9 9.3 2.4e-30 105.9 6.5 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EPE25987.1 - 3.3e-07 29.7 0.1 1.2e-06 27.8 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE25987.1 - 0.00014 21.9 0.9 0.028 14.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPE25987.1 - 0.00033 20.6 0.1 0.0011 19.0 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EPE25987.1 - 0.001 18.2 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EPE25987.1 - 0.0014 18.4 0.4 0.014 15.2 0.3 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EPE25987.1 - 0.019 15.0 0.2 0.15 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPE25987.1 - 0.033 13.6 0.1 0.094 12.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain OTT_1508_deam PF14441.1 EPE25988.1 - 7.1e-08 32.3 2.1 1.9e-07 30.9 1.5 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Aminotran_1_2 PF00155.16 EPE25989.1 - 3.2e-37 128.3 0.0 4.2e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EPE25989.1 - 0.00064 18.1 0.0 0.0012 17.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3755 PF12579.3 EPE25989.1 - 0.11 11.8 0.2 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) Glucan_synthase PF02364.10 EPE25990.1 - 0 1471.9 0.0 0 1471.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EPE25990.1 - 7.9e-39 132.1 0.6 1.8e-38 131.0 0.4 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 XhlA PF10779.4 EPE25990.1 - 0.54 10.2 0.6 1.4 8.8 0.4 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Glyco_hydro_72 PF03198.9 EPE25991.1 - 1.2e-129 431.8 1.0 1.6e-129 431.4 0.7 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EPE25991.1 - 2.8e-25 88.6 7.8 5.2e-25 87.7 4.8 2.0 2 0 0 2 2 2 1 X8 domain RasGAP PF00616.14 EPE25992.1 - 4.1e-54 183.2 0.0 4.1e-54 183.2 0.0 2.5 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase SprT-like PF10263.4 EPE25992.1 - 1.3e-48 164.6 1.2 2.2e-48 163.9 0.8 1.4 1 0 0 1 1 1 1 SprT-like family RasGAP_C PF03836.10 EPE25992.1 - 3.4e-30 104.6 4.0 1.2e-29 102.8 2.7 2.0 1 0 0 1 1 1 1 RasGAP C-terminus HMG_box PF00505.14 EPE25992.1 - 0.017 15.3 0.0 0.052 13.8 0.0 1.8 1 0 0 1 1 1 0 HMG (high mobility group) box Peptidase_MA_2 PF13485.1 EPE25992.1 - 0.1 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily AA_permease PF00324.16 EPE25993.1 - 6.1e-124 413.9 38.7 7.1e-124 413.7 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE25993.1 - 1.3e-28 99.7 44.0 1.5e-28 99.4 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease RCR PF12273.3 EPE25995.1 - 9.3 6.8 16.1 10 6.6 11.2 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red HET PF06985.6 EPE25996.1 - 1.2e-21 77.3 8.2 7.1e-19 68.3 0.6 2.9 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.21 EPE25997.1 - 9.4e-11 41.4 21.3 0.0016 18.6 0.3 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE25997.1 - 3.3e-08 33.2 18.6 0.016 15.4 0.3 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE25997.1 - 0.00044 20.3 15.5 0.84 10.0 0.4 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2HC_2 PF13913.1 EPE25997.1 - 0.061 13.0 0.7 0.061 13.0 0.5 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Tmemb_55A PF09788.4 EPE25997.1 - 0.17 11.0 3.2 4.5 6.3 0.1 2.3 1 1 1 2 2 2 0 Transmembrane protein 55A zf-Di19 PF05605.7 EPE25997.1 - 0.91 9.6 6.8 1.6 8.9 2.3 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EPE25997.1 - 2.1 8.5 15.0 2.3 8.4 3.0 4.0 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ank_2 PF12796.2 EPE25998.1 - 8e-34 115.8 0.6 1.7e-20 73.1 0.2 3.1 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE25998.1 - 3.3e-27 92.8 0.9 2.5e-07 30.1 0.2 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EPE25998.1 - 8.2e-22 77.1 1.9 3.3e-11 43.3 0.1 5.6 1 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE25998.1 - 1.3e-21 74.4 2.9 2e-05 24.3 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EPE25998.1 - 1.8e-16 59.7 1.1 0.00068 19.8 0.1 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) NAD_binding_6 PF08030.7 EPE25999.1 - 1.8e-19 70.1 0.1 3.4e-17 62.7 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPE25999.1 - 3.7e-19 69.0 10.8 3.7e-19 69.0 7.5 3.1 4 0 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EPE25999.1 - 5.5e-12 45.4 0.1 1.3e-10 41.0 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EPE25999.1 - 0.13 12.8 0.0 0.57 10.7 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF1690 PF07956.6 EPE26000.1 - 8.6e-35 119.7 1.2 1e-34 119.5 0.9 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Lebercilin PF15619.1 EPE26000.1 - 0.036 13.4 2.7 0.22 10.9 0.3 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Cep57_CLD_2 PF14197.1 EPE26000.1 - 0.26 11.2 4.7 0.17 11.8 1.2 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Lzipper-MIP1 PF14389.1 EPE26000.1 - 0.73 9.9 3.7 0.79 9.8 0.9 2.1 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Med9 PF07544.8 EPE26000.1 - 2.8 7.7 6.6 0.91 9.3 0.2 2.8 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TYW3 PF02676.9 EPE26001.1 - 1.1e-57 194.4 0.0 1.4e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 RRM_6 PF14259.1 EPE26002.1 - 0.00017 21.5 0.1 0.00042 20.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ARPC4 PF05856.7 EPE26003.1 - 1.6e-76 255.4 4.3 1.8e-76 255.2 3.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) ARID PF01388.16 EPE26005.1 - 5.4e-19 67.8 0.1 5.4e-19 67.8 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Img2 PF05046.9 EPE26006.1 - 2.2e-20 72.6 0.6 3.2e-20 72.1 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Propep_M14 PF02244.11 EPE26006.1 - 0.0008 19.0 0.3 0.87 9.2 0.0 2.9 1 1 1 2 2 2 2 Carboxypeptidase activation peptide SUI1 PF01253.17 EPE26006.1 - 0.044 13.6 1.0 0.064 13.0 0.7 1.2 1 0 0 1 1 1 0 Translation initiation factor SUI1 Axin_b-cat_bind PF08833.5 EPE26006.1 - 0.07 12.8 1.5 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Axin beta-catenin binding domain eIF3_N PF09440.5 EPE26007.1 - 2.2e-45 154.0 0.6 5e-45 152.9 0.4 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EPE26007.1 - 5.8e-15 55.4 0.0 5.2e-14 52.4 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EPE26007.1 - 0.039 13.3 0.3 0.17 11.2 0.0 2.0 1 1 1 2 2 2 0 26S proteasome subunit RPN7 EVE PF01878.13 EPE26008.1 - 9e-52 174.9 0.2 1.8e-51 173.9 0.2 1.4 1 0 0 1 1 1 1 EVE domain Mhr1 PF12829.2 EPE26012.1 - 0.02 14.7 0.5 0.041 13.6 0.3 1.5 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination Acyl_transf_3 PF01757.17 EPE26014.1 - 4.6e-28 98.0 26.3 6.2e-28 97.6 18.2 1.2 1 0 0 1 1 1 1 Acyltransferase family GFA PF04828.9 EPE26015.1 - 2.1e-19 69.2 0.0 2.8e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 EPE26015.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) WD40 PF00400.27 EPE26016.1 - 0.03 14.2 0.2 21 5.1 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat MFS_1 PF07690.11 EPE26017.1 - 1.3e-39 135.9 36.8 3.6e-39 134.4 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26017.1 - 2.6e-10 39.4 8.6 2.6e-10 39.4 6.0 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EPE26017.1 - 4.6e-09 35.0 1.6 6.8e-09 34.4 1.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 EPE26017.1 - 0.0011 19.0 1.8 0.0011 19.0 1.3 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) Asp-Al_Ex PF06826.7 EPE26017.1 - 0.0018 17.8 4.0 0.0018 17.8 2.8 2.0 2 0 0 2 2 2 1 Predicted Permease Membrane Region eIF2A PF08662.6 EPE26018.1 - 8.9e-79 263.7 0.1 2.6e-77 258.9 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EPE26018.1 - 4.8e-05 23.0 1.4 2.4 8.1 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat CDV3 PF15359.1 EPE26018.1 - 0.0034 17.4 0.2 0.0034 17.4 0.2 2.9 3 0 0 3 3 3 1 Carnitine deficiency-associated protein 3 DUF2967 PF11179.3 EPE26018.1 - 0.39 10.1 14.1 0.59 9.5 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Med15 PF09606.5 EPE26018.1 - 1.4 7.0 30.6 1.8 6.6 21.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4544 PF15077.1 EPE26018.1 - 2 7.8 4.0 3.5 7.0 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) PD40 PF07676.7 EPE26018.1 - 3.3 7.4 6.3 11 5.7 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Apc1 PF12859.2 EPE26019.1 - 1.9e-26 92.2 0.0 7.5e-26 90.3 0.0 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EPE26019.1 - 3.4e-06 26.9 1.5 0.37 11.1 0.1 4.5 4 0 0 4 4 4 3 Proteasome/cyclosome repeat CsbD PF05532.7 EPE26020.1 - 0.0037 16.8 17.0 0.0037 16.8 11.8 3.7 2 1 1 3 3 3 1 CsbD-like DUF883 PF05957.8 EPE26020.1 - 0.57 10.6 5.2 0.6 10.5 1.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EPE26020.1 - 0.71 10.2 9.5 1.1 9.6 3.9 2.3 1 1 1 2 2 2 0 YtxH-like protein ISG65-75 PF11727.3 EPE26020.1 - 0.76 8.7 8.3 0.97 8.4 5.7 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein CtnDOT_TraJ PF07863.6 EPE26020.1 - 2.4 8.6 5.9 3.2 8.2 3.4 1.9 1 1 1 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon LEA_4 PF02987.11 EPE26020.1 - 8.2 6.3 22.0 6.7 6.6 11.6 2.9 2 1 0 2 2 2 0 Late embryogenesis abundant protein Sec7 PF01369.15 EPE26021.1 - 8.6e-45 152.7 0.2 5.7e-44 150.0 0.1 2.1 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 EPE26021.1 - 4.2e-19 68.8 0.0 8.5e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1510 PF07423.6 EPE26022.1 - 3.6 6.8 20.9 5 6.4 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2413 PF10310.4 EPE26022.1 - 5.9 5.5 15.3 7.4 5.2 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) GAS PF13851.1 EPE26023.1 - 0.00031 19.9 0.1 0.00036 19.7 0.1 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Rootletin PF15035.1 EPE26023.1 - 0.0051 16.8 0.0 0.0058 16.6 0.0 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Mad3_BUB1_I PF08311.7 EPE26023.1 - 0.02 14.6 0.2 0.024 14.4 0.1 1.1 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Ank_2 PF12796.2 EPE26026.1 - 7.9e-16 58.1 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPE26026.1 - 1.3e-15 57.0 1.0 9e-09 35.2 0.2 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EPE26026.1 - 8.8e-14 50.5 0.2 1.7e-08 33.8 0.2 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EPE26026.1 - 5.4e-12 45.8 0.4 4.6e-07 30.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE26026.1 - 1.1e-08 34.4 0.0 0.00035 20.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat ECH PF00378.15 EPE26027.1 - 3e-53 180.4 0.4 2.1e-48 164.6 0.2 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family HET PF06985.6 EPE26028.1 - 8.2e-36 123.2 3.6 1.4e-35 122.4 2.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RTA1 PF04479.8 EPE26029.1 - 2.4e-12 46.8 5.3 4.4e-12 45.9 3.6 1.3 1 0 0 1 1 1 1 RTA1 like protein Sec3_C PF09763.4 EPE26030.1 - 0.29 9.2 2.9 0.88 7.6 2.5 1.4 2 0 0 2 2 2 0 Exocyst complex component Sec3 SHMT PF00464.14 EPE26031.1 - 3.6e-207 687.4 0.0 4.3e-207 687.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 EPE26031.1 - 0.0091 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPE26031.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase HAD_2 PF13419.1 EPE26032.1 - 3.7e-29 102.1 0.0 4.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE26032.1 - 5.3e-06 26.0 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EPE26032.1 - 0.0046 17.4 0.0 0.15 12.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HNH PF01844.18 EPE26033.1 - 0.00011 21.9 1.7 0.00024 20.8 1.2 1.6 1 0 0 1 1 1 1 HNH endonuclease Clp1 PF06807.9 EPE26035.1 - 6.6e-09 35.8 0.0 1.4e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EPE26035.1 - 6.2e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EPE26035.1 - 0.00012 22.8 0.0 0.0022 18.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPE26035.1 - 0.0068 16.2 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPE26035.1 - 0.042 14.1 1.3 0.18 12.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain COBRA PF04833.10 EPE26035.1 - 0.056 13.2 0.1 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 COBRA-like protein MutS_V PF00488.16 EPE26035.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 MutS domain V AAA_14 PF13173.1 EPE26035.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPE26035.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.1 3 0 0 3 3 3 0 RNA helicase RNA_polI_A34 PF08208.6 EPE26036.1 - 7.4e-35 120.4 4.7 7.4e-35 120.4 3.2 3.1 2 1 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 PAF-AH_p_II PF03403.8 EPE26037.1 - 5.5e-19 67.7 0.0 1.5e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EPE26037.1 - 1.7e-15 57.0 0.1 2.8e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE26037.1 - 3.9e-07 30.1 0.2 1.2e-06 28.5 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EPE26037.1 - 2.3e-05 23.4 0.0 5.7e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPE26037.1 - 0.0018 17.1 0.3 1 8.1 0.1 2.3 2 0 0 2 2 2 2 Chlorophyllase Peptidase_S9 PF00326.16 EPE26037.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 EPE26037.1 - 0.019 14.5 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 EPE26037.1 - 0.13 10.7 0.4 1.7 7.0 0.1 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) O-FucT PF10250.4 EPE26038.1 - 6.2e-11 41.9 0.0 9e-09 34.8 0.0 2.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PUA_2 PF14306.1 EPE26038.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 PUA-like domain AAA PF00004.24 EPE26039.1 - 1.6e-45 154.5 0.4 4.5e-45 153.0 0.0 1.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPE26039.1 - 4.6e-09 36.1 0.3 1.6e-08 34.3 0.1 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPE26039.1 - 5.5e-08 32.9 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPE26039.1 - 5.5e-07 29.7 0.0 1.7e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE26039.1 - 9.4e-07 29.0 0.7 0.0003 20.9 0.5 2.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EPE26039.1 - 4.9e-06 25.6 0.0 9.3e-06 24.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EPE26039.1 - 0.00015 21.6 0.0 0.00075 19.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPE26039.1 - 0.00043 19.3 0.0 0.001 18.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EPE26039.1 - 0.00048 20.2 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 EPE26039.1 - 0.00052 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE26039.1 - 0.00087 20.0 0.0 0.005 17.6 0.0 2.2 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 EPE26039.1 - 0.0013 17.5 0.0 0.0023 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus NACHT PF05729.7 EPE26039.1 - 0.0015 18.2 0.4 0.056 13.0 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EPE26039.1 - 0.0015 18.2 0.2 0.0037 16.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EPE26039.1 - 0.0025 17.5 0.0 0.0083 15.8 0.0 1.9 2 0 0 2 2 1 1 NTPase Zeta_toxin PF06414.7 EPE26039.1 - 0.0032 16.6 0.1 0.012 14.7 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.1 EPE26039.1 - 0.0039 16.7 0.1 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EPE26039.1 - 0.0043 16.6 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EPE26039.1 - 0.0048 16.5 0.0 0.037 13.6 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EPE26039.1 - 0.0051 17.1 0.6 0.81 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPE26039.1 - 0.0053 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPE26039.1 - 0.0061 16.2 0.5 0.077 12.6 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase Mg_chelatase PF01078.16 EPE26039.1 - 0.0069 15.5 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EPE26039.1 - 0.008 15.6 0.8 0.084 12.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 EPE26039.1 - 0.012 15.2 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EPE26039.1 - 0.013 14.9 0.3 0.03 13.7 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_30 PF13604.1 EPE26039.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPE26039.1 - 0.016 15.5 0.0 0.047 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EPE26039.1 - 0.02 14.0 1.0 0.46 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC Bac_DnaA PF00308.13 EPE26039.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.21 EPE26039.1 - 0.048 13.1 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.9 EPE26039.1 - 0.072 11.3 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Sigma54_activ_2 PF14532.1 EPE26039.1 - 0.077 13.0 0.1 0.51 10.3 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain Cast PF10174.4 EPE26039.1 - 0.084 10.9 2.0 0.15 10.0 0.7 1.7 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone NB-ARC PF00931.17 EPE26039.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EPE26039.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mis14 PF08641.7 EPE26041.1 - 3e-05 24.1 0.9 3e-05 24.1 0.6 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Nup88 PF10168.4 EPE26041.1 - 0.011 13.5 0.3 0.014 13.2 0.2 1.2 1 0 0 1 1 1 0 Nuclear pore component P34-Arc PF04045.9 EPE26041.1 - 0.075 12.2 0.2 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Arp2/3 complex, 34 kD subunit p34-Arc Pox_polyA_pol_N PF12630.2 EPE26041.1 - 0.14 12.3 0.4 0.41 10.7 0.1 1.9 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain tRNA_m1G_MT PF01746.16 EPE26042.1 - 5e-35 120.7 0.0 3e-28 98.6 0.0 2.3 1 1 1 2 2 2 2 tRNA (Guanine-1)-methyltransferase SR-25 PF10500.4 EPE26042.1 - 0.14 11.6 11.7 0.03 13.7 3.0 2.9 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein MutS_V PF00488.16 EPE26043.1 - 2e-96 321.9 0.0 3e-96 321.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPE26043.1 - 8.4e-38 130.2 0.7 1.5e-37 129.4 0.5 1.4 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EPE26043.1 - 7.7e-20 71.3 0.0 2.9e-19 69.5 0.0 2.1 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.15 EPE26043.1 - 3.4e-19 68.9 0.0 1.5e-18 66.8 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EPE26043.1 - 5.7e-17 61.6 0.4 1.6e-16 60.2 0.3 1.8 1 0 0 1 1 1 1 MutS family domain IV Peptidase_M16 PF00675.15 EPE26043.1 - 0.044 13.5 0.1 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Folliculin PF11704.3 EPE26044.1 - 8.8e-31 106.7 0.0 2.2e-30 105.4 0.0 1.7 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport DEAD PF00270.24 EPE26045.1 - 4.5e-42 143.4 0.0 6.2e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE26045.1 - 1.4e-23 82.5 0.1 3.2e-23 81.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DNA_primase_S PF01896.14 EPE26046.1 - 1.2e-54 184.0 0.1 2e-54 183.3 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DNA_pol_A_exo1 PF01612.15 EPE26047.1 - 1.4e-43 148.4 0.1 2.8e-43 147.4 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EPE26047.1 - 9.6e-26 89.9 0.3 5.6e-25 87.4 0.1 2.2 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 EPE26047.1 - 1.2e-11 44.1 0.0 2.7e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain UPF0203 PF05254.7 EPE26048.1 - 1.9e-29 101.2 1.9 2.7e-29 100.7 1.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EPE26048.1 - 0.0034 17.3 2.5 0.0035 17.3 0.3 2.0 2 1 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EPE26048.1 - 0.0056 16.4 3.9 0.17 11.7 0.1 2.4 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 EPE26048.1 - 0.088 12.7 1.8 0.43 10.5 1.3 2.0 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF3128 PF11326.3 EPE26048.1 - 0.11 12.6 1.4 0.16 12.0 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.12 EPE26048.1 - 0.25 11.3 7.4 0.71 9.9 1.0 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Gpi1 PF05024.10 EPE26049.1 - 1.2e-63 214.2 9.1 2.6e-63 213.1 6.3 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Tom37_C PF11801.3 EPE26049.1 - 0.0016 18.3 0.3 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 Tom37 C-terminal domain Ferric_reduct PF01794.14 EPE26050.1 - 3.1e-15 56.3 11.2 6.3e-15 55.3 6.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EPE26050.1 - 7.7e-12 45.0 0.1 2.6e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EPE26050.1 - 8.8e-11 41.9 0.0 0.00016 21.6 0.0 2.7 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EPE26050.1 - 0.015 15.3 0.0 1.4 9.0 0.0 2.4 1 1 1 2 2 2 0 Oxidoreductase FAD-binding domain YhhN PF07947.9 EPE26050.1 - 3.8 6.8 12.1 0.12 11.7 2.7 2.4 3 0 0 3 3 3 0 YhhN-like protein Prefoldin PF02996.12 EPE26051.1 - 6.6e-32 109.6 0.0 2.9e-31 107.6 0.0 1.8 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 EPE26051.1 - 0.00022 20.9 0.3 0.0036 17.0 0.0 2.2 2 0 0 2 2 2 1 Prefoldin subunit DIL PF01843.14 EPE26051.1 - 0.064 13.1 0.0 0.18 11.6 0.0 1.7 1 1 1 2 2 2 0 DIL domain CRAL_TRIO PF00650.15 EPE26052.1 - 1.7e-35 121.8 0.0 2.6e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPE26052.1 - 2.1e-09 37.3 0.1 6.6e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPE26052.1 - 0.00017 21.5 0.0 0.00047 20.0 0.0 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain W2 PF02020.13 EPE26053.1 - 4.9e-19 68.0 4.0 1.2e-18 66.8 2.8 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EPE26053.1 - 1.2e-11 43.5 6.4 0.0014 18.0 0.0 4.3 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EPE26053.1 - 2.9e-06 26.7 0.0 4.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EPE26053.1 - 5.5e-05 22.6 8.3 0.0097 15.4 1.5 3.4 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EPE26053.1 - 0.00034 20.7 0.0 0.00069 19.7 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain SAM_2 PF07647.12 EPE26054.1 - 8.7e-17 60.7 0.0 1.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EPE26054.1 - 5e-14 52.5 0.0 9.5e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 EPE26054.1 - 5.2e-14 52.1 0.0 9.2e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SNF2_N PF00176.18 EPE26055.1 - 3.6e-70 236.1 0.0 5.5e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EPE26055.1 - 3.4e-25 88.0 0.0 8.1e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EPE26055.1 - 9.2e-13 47.8 0.0 2.4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EPE26055.1 - 2.5e-06 27.3 9.2 5.5e-06 26.3 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EPE26055.1 - 3.7e-05 23.6 0.0 0.00014 21.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EPE26055.1 - 5.4e-05 22.7 10.2 0.00011 21.7 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA_22 PF13401.1 EPE26055.1 - 0.005 16.9 0.0 0.33 11.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain zf-RING_2 PF13639.1 EPE26055.1 - 0.033 14.0 11.3 0.068 13.0 7.8 1.5 1 0 0 1 1 1 0 Ring finger domain UBA_4 PF14555.1 EPE26055.1 - 0.04 13.4 0.0 0.16 11.5 0.0 2.0 1 0 0 1 1 1 0 UBA-like domain zf-C3HC4_3 PF13920.1 EPE26055.1 - 0.4 10.3 9.6 0.84 9.3 6.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE26055.1 - 0.78 9.5 9.4 2.2 8.1 6.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain SQS_PSY PF00494.14 EPE26056.1 - 5.2e-48 163.6 0.0 8.5e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Pyr_redox_2 PF07992.9 EPE26057.1 - 1.2e-28 100.3 0.1 3.6e-19 69.4 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE26057.1 - 1.7e-14 53.9 0.0 8.7e-12 45.2 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE26057.1 - 3.1e-05 24.1 0.7 0.037 14.0 0.2 3.8 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EPE26057.1 - 0.13 12.5 0.5 5.6 7.2 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding Acetyltransf_1 PF00583.19 EPE26058.1 - 9.1e-09 35.2 0.0 4.3e-08 33.0 0.1 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE26058.1 - 1.8e-06 27.9 0.0 4.9e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE26058.1 - 8.2e-05 22.7 0.1 0.00017 21.6 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE26058.1 - 0.00015 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EPE26058.1 - 0.00032 20.6 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE26058.1 - 0.00086 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EPE26058.1 - 0.044 13.6 0.1 0.28 11.0 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain S4 PF01479.20 EPE26059.1 - 8.9e-15 53.8 0.0 2.1e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EPE26059.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 S4 domain DUF2927 PF11150.3 EPE26059.1 - 0.046 13.4 0.3 0.046 13.4 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2927) Con-6 PF10346.4 EPE26059.1 - 0.047 13.1 0.6 0.11 11.8 0.4 1.6 1 0 0 1 1 1 0 Conidiation protein 6 CHAD PF05235.9 EPE26059.1 - 5 6.6 15.4 0.95 8.9 7.7 1.8 1 1 1 2 2 2 0 CHAD domain Carn_acyltransf PF00755.15 EPE26060.1 - 4.1e-181 603.0 0.0 4.7e-181 602.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Eaf7 PF07904.8 EPE26061.1 - 1.1e-29 102.2 0.3 2.3e-29 101.1 0.2 1.5 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Spc97_Spc98 PF04130.8 EPE26062.1 - 1.1e-82 278.1 0.8 1.5e-82 277.7 0.6 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family ETC_C1_NDUFA5 PF04716.9 EPE26063.1 - 2.3e-21 75.0 0.6 4.4e-21 74.1 0.1 1.7 2 0 0 2 2 2 1 ETC complex I subunit conserved region Tub_2 PF04525.7 EPE26064.1 - 1.4e-05 24.6 0.0 3.1e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Tubby C 2 Acetyltransf_1 PF00583.19 EPE26065.1 - 9.8e-07 28.7 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE26065.1 - 2.4e-06 27.5 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE26065.1 - 0.00064 19.5 0.2 0.0019 18.0 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE26065.1 - 0.0054 16.8 0.0 0.0092 16.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE26065.1 - 0.069 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fib_alpha PF08702.5 EPE26066.1 - 0.058 13.5 3.3 3.7 7.6 0.6 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TSC22 PF01166.13 EPE26066.1 - 1.4 8.9 5.4 0.8 9.7 0.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family cIII PF08134.6 EPE26066.1 - 1.5 8.5 3.7 13 5.5 0.0 2.9 2 0 0 2 2 2 0 cIII protein family DUF2968 PF11180.3 EPE26066.1 - 1.6 8.0 16.8 0.63 9.3 0.6 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2968) DUF2046 PF09755.4 EPE26066.1 - 1.6 7.5 11.3 0.14 10.9 3.0 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) MerR-DNA-bind PF09278.6 EPE26066.1 - 2.2 8.7 12.8 0.71 10.3 0.5 2.4 2 0 0 2 2 2 0 MerR, DNA binding DivIC PF04977.10 EPE26066.1 - 2.3 7.7 10.1 0.23 10.9 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.6 EPE26066.1 - 3 7.8 4.6 5.7 6.9 0.6 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Nsp1_C PF05064.8 EPE26066.1 - 3.8 7.1 8.6 2 8.0 2.6 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region Surfac_D-trimer PF09006.6 EPE26066.1 - 7.1 6.4 9.7 5.4 6.8 0.2 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation MFS_1 PF07690.11 EPE26067.1 - 1.5e-32 112.6 31.6 6.2e-29 100.8 3.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26067.1 - 8.7e-10 37.7 2.4 8.7e-10 37.7 1.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EPE26067.1 - 9.2e-05 21.0 20.6 0.00069 18.1 1.9 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 EPE26067.1 - 0.14 10.2 4.9 0.074 11.1 1.1 2.1 2 1 1 3 3 3 0 Transmembrane secretion effector GDI PF00996.13 EPE26068.1 - 2.8e-177 589.4 0.0 3.3e-177 589.1 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EPE26068.1 - 0.016 15.1 0.1 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.8 EPE26069.1 - 1.3e-19 69.8 0.2 2.2e-19 69.1 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.7 EPE26069.1 - 0.14 11.4 0.6 0.23 10.6 0.4 1.3 1 0 0 1 1 1 0 Clc-like MRP-L20 PF12824.2 EPE26069.1 - 0.91 9.4 6.0 0.76 9.7 2.3 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Fungal_trans PF04082.13 EPE26072.1 - 1.3e-16 60.2 0.0 2.4e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EPE26072.1 - 1.4e-05 25.1 1.2 1.4e-05 25.1 0.8 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPE26072.1 - 2.8e-05 24.1 14.2 0.0016 18.5 4.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EPE26072.1 - 0.00067 19.7 3.1 0.002 18.1 2.2 1.8 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding LRR_8 PF13855.1 EPE26073.1 - 0.0087 15.7 0.6 0.07 12.8 0.1 2.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 EPE26073.1 - 0.14 11.8 7.5 0.43 10.2 0.1 3.4 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) PsbI PF02532.9 EPE26074.1 - 1.2 8.7 11.0 2.6 7.7 0.9 3.1 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) eIF3g PF12353.3 EPE26075.1 - 1.8e-45 153.9 4.0 1.8e-45 153.9 2.8 1.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EPE26075.1 - 4.8e-17 61.3 0.1 9.1e-17 60.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE26075.1 - 7.6e-12 45.0 0.1 1.4e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE26075.1 - 4.6e-07 29.5 0.2 1.2e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.15 EPE26076.1 - 2.4e-263 874.5 16.5 2.7e-263 874.3 11.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPE26076.1 - 1.7e-15 56.4 5.0 1.7e-13 49.8 1.3 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EPE26076.1 - 0.00075 19.1 0.0 0.0027 17.3 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EPE26076.1 - 0.0035 17.1 8.3 58 3.5 5.7 4.2 1 1 0 1 1 1 0 Cell division protein FtsA DUF4363 PF14276.1 EPE26076.1 - 0.0049 16.5 2.8 0.011 15.4 1.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4363) DUF2415 PF10313.4 EPE26077.1 - 4.7e-11 42.1 0.0 1.2e-09 37.6 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) PD40 PF07676.7 EPE26077.1 - 0.0099 15.5 0.1 20 4.9 0.0 3.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40 PF00400.27 EPE26077.1 - 0.032 14.1 7.8 3.2 7.7 0.0 5.4 5 2 0 5 5 5 0 WD domain, G-beta repeat DAO PF01266.19 EPE26078.1 - 4.5e-55 187.0 0.0 5.9e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase PAH PF02671.16 EPE26078.1 - 2.7e-07 30.0 0.0 6.7e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Paired amphipathic helix repeat Pyr_redox_3 PF13738.1 EPE26078.1 - 0.00052 20.1 0.0 0.0018 18.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE26078.1 - 0.00058 19.8 0.8 0.0013 18.6 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE26078.1 - 0.0085 15.9 0.5 0.017 14.9 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPE26078.1 - 0.044 12.8 3.9 0.15 11.0 2.7 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.20 EPE26078.1 - 0.06 13.2 0.3 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.13 EPE26078.1 - 0.093 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 EPE26078.1 - 0.11 10.9 0.8 0.17 10.3 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 EPE26078.1 - 0.13 11.6 0.4 0.32 10.4 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 EPE26078.1 - 0.19 10.5 1.4 0.52 9.1 1.0 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EPE26078.1 - 0.19 11.4 0.3 0.38 10.4 0.2 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GMC_oxred_C PF05199.8 EPE26080.1 - 8.7e-14 52.0 0.0 1.1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EPE26080.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase MFS_1 PF07690.11 EPE26081.1 - 2.4e-49 167.9 36.0 2.4e-49 167.9 24.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26081.1 - 3.1e-12 45.8 28.9 3.1e-12 45.8 20.0 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EPE26081.1 - 0.0001 20.5 5.1 0.0035 15.4 1.0 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Aconitase PF00330.15 EPE26082.1 - 2.6e-181 603.1 0.2 3.2e-181 602.8 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPE26082.1 - 7.3e-46 155.5 0.0 2.3e-45 153.8 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF2418 PF10332.4 EPE26084.1 - 6.1e-33 113.0 0.6 6.1e-33 113.0 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.12 EPE26085.1 - 1.5e-31 108.5 0.0 1.8e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.10 EPE26086.1 - 3.7e-26 91.9 0.9 4.3e-26 91.7 0.6 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EPE26086.1 - 0.0007 19.6 0.1 0.0016 18.4 0.1 1.6 1 1 0 1 1 1 1 ML-like domain EBP PF05241.7 EPE26087.1 - 1.5e-65 219.8 9.6 1.7e-65 219.6 6.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein WBP-1 PF11669.3 EPE26087.1 - 0.035 14.1 0.1 0.083 12.9 0.1 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 Sprouty PF05210.8 EPE26087.1 - 0.16 12.0 0.4 0.29 11.1 0.1 1.5 1 1 0 1 1 1 0 Sprouty protein (Spry) DUF605 PF04652.11 EPE26088.1 - 1.4 8.2 5.6 1.3 8.3 3.9 1.1 1 0 0 1 1 1 0 Vta1 like PHD PF00628.24 EPE26089.1 - 3.7e-07 29.7 9.3 7.4e-07 28.7 6.5 1.5 1 0 0 1 1 1 1 PHD-finger Glycos_transf_4 PF00953.16 EPE26090.1 - 9e-33 113.3 9.2 9e-33 113.3 6.4 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 WD40 PF00400.27 EPE26091.1 - 1.6e-25 88.0 0.1 2.9e-06 26.9 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat IF4E PF01652.13 EPE26093.1 - 0.015 14.8 0.2 0.02 14.4 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E DUF3336 PF11815.3 EPE26094.1 - 4.2 6.8 5.2 6.2 6.3 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3336) SOG2 PF10428.4 EPE26095.1 - 2.2 6.8 14.7 2.6 6.6 10.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.4 EPE26095.1 - 7.3 4.7 17.5 8.6 4.5 12.1 1.1 1 0 0 1 1 1 0 Transmembrane protein HlyIII PF03006.15 EPE26096.1 - 0.69 9.2 15.8 0.02 14.3 4.5 2.3 1 1 2 3 3 3 0 Haemolysin-III related DUF4267 PF14087.1 EPE26097.1 - 2.6e-10 39.8 4.2 2.9e-10 39.7 2.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) MFS_1 PF07690.11 EPE26098.1 - 6.1e-38 130.4 51.6 4.1e-37 127.7 33.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26098.1 - 1.8e-13 49.9 4.9 1.8e-13 49.9 3.4 3.5 2 1 2 4 4 4 1 Sugar (and other) transporter p450 PF00067.17 EPE26099.1 - 5.4e-27 94.4 0.0 7.7e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 FlbD PF06289.6 EPE26099.1 - 0.02 14.2 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein (FlbD) p450 PF00067.17 EPE26100.1 - 2.4e-29 102.1 0.0 3.1e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Phenyl_P_gamma PF09662.5 EPE26100.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) Glyco_hydro_53 PF07745.8 EPE26100.1 - 0.28 9.9 0.1 0.57 8.9 0.1 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 53 Mob1_phocein PF03637.12 EPE26102.1 - 2.9e-24 85.6 0.0 4.7e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 EPE26103.1 - 4.6e-41 140.2 0.3 6.5e-41 139.7 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EPE26103.1 - 0.006 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain ATP_bind_1 PF03029.12 EPE26103.1 - 0.011 15.2 0.7 0.67 9.4 0.3 2.2 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EPE26103.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.22 EPE26103.1 - 0.014 14.8 0.9 0.21 11.0 0.6 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPE26103.1 - 0.015 15.2 0.2 0.035 14.0 0.2 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EPE26103.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 EPE26103.1 - 0.019 15.1 0.4 0.059 13.5 0.0 2.0 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 EPE26103.1 - 0.02 13.6 0.7 1.8 7.2 0.0 2.8 3 0 0 3 3 3 0 ArgK protein AAA_10 PF12846.2 EPE26103.1 - 0.031 13.7 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain APS_kinase PF01583.15 EPE26103.1 - 0.044 13.4 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.22 EPE26103.1 - 0.047 13.9 0.4 0.16 12.2 0.1 2.0 2 1 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 EPE26103.1 - 0.054 12.5 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 EPE26103.1 - 0.069 12.8 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EPE26103.1 - 0.085 12.6 0.1 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EPE26103.1 - 0.097 12.5 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EPE26103.1 - 0.1 11.6 0.2 6.4 5.6 0.0 2.4 3 0 0 3 3 3 0 Septin AAA_29 PF13555.1 EPE26103.1 - 0.1 12.1 0.0 0.31 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EPE26103.1 - 0.1 11.7 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EPE26103.1 - 0.12 12.6 0.1 0.31 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EPE26103.1 - 0.22 12.0 1.3 1.4 9.4 0.0 2.9 3 1 0 3 3 3 0 Miro-like protein CAP_N PF01213.14 EPE26104.1 - 0.23 10.7 4.1 0.31 10.3 2.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RGS PF00615.14 EPE26105.1 - 6.8e-34 116.4 0.0 1.9e-33 115.0 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EPE26105.1 - 1.4e-23 82.3 0.1 2.9e-19 68.5 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RGS-like PF09128.6 EPE26105.1 - 0.038 13.4 0.1 3 7.3 0.0 2.5 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain CDC73 PF05179.9 EPE26106.1 - 8.3e-47 159.8 0.0 1.2e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Dak1 PF02733.12 EPE26108.1 - 4.7e-81 271.8 0.0 5.7e-81 271.5 0.0 1.0 1 0 0 1 1 1 1 Dak1 domain MF_alpha_N PF05436.6 EPE26108.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Dak2 PF02734.12 EPE26109.1 - 5.7e-44 149.8 0.1 1.9e-43 148.1 0.0 1.9 2 0 0 2 2 2 1 DAK2 domain TF_Zn_Ribbon PF08271.7 EPE26110.1 - 0.0039 16.4 0.5 0.082 12.2 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding p450 PF00067.17 EPE26111.1 - 4.6e-51 173.7 0.0 7.9e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 JSRP PF15312.1 EPE26112.1 - 0.081 12.9 0.2 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Hid1 PF12722.2 EPE26112.1 - 0.71 7.4 6.0 0.82 7.2 4.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DASH_Ask1 PF08655.5 EPE26113.1 - 3.3e-05 23.6 4.1 0.012 15.3 0.0 2.6 2 0 0 2 2 2 2 DASH complex subunit Ask1 Rhodanese PF00581.15 EPE26114.1 - 7.9e-15 55.1 0.0 1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Yip1 PF04893.12 EPE26115.1 - 1.4e-11 44.2 19.3 2.8e-11 43.2 13.3 1.6 1 1 0 1 1 1 1 Yip1 domain ubiquitin PF00240.18 EPE26116.1 - 1.7e-31 107.3 0.5 3.8e-31 106.3 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EPE26116.1 - 3e-29 100.3 9.8 6.6e-29 99.2 6.8 1.6 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EPE26116.1 - 3.6e-17 61.8 0.9 7.1e-17 60.8 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RRN7 PF11781.3 EPE26116.1 - 9.8e-06 24.9 3.3 9.8e-06 24.9 2.3 1.8 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 Ubiquitin_2 PF14560.1 EPE26116.1 - 0.00034 20.8 0.1 0.001 19.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EPE26116.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like eIF-5a PF01287.15 EPE26117.1 - 1.6e-24 85.6 2.0 2.2e-24 85.1 1.4 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EPE26117.1 - 0.0014 18.2 0.4 0.0033 17.0 0.3 1.7 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EPE26117.1 - 0.002 17.9 0.4 0.0046 16.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.7 EPE26118.1 - 4.3e-128 428.0 6.3 5.3e-128 427.7 4.4 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EPE26118.1 - 1.7e-06 26.5 1.6 1.7e-06 26.5 1.1 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec3 Mer2 PF09074.5 EPE26118.1 - 0.0039 17.1 1.6 0.012 15.4 0.1 2.4 3 0 0 3 3 3 1 Mer2 DUF1664 PF07889.7 EPE26118.1 - 0.15 11.8 0.7 0.37 10.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RabGAP-TBC PF00566.13 EPE26119.1 - 9.6e-22 77.5 0.0 1.5e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.4 EPE26120.1 - 6.7e-81 271.9 0.0 2.9e-80 269.8 0.0 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.22 EPE26121.1 - 6.6e-32 110.4 0.0 6.6e-32 110.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EPE26121.1 - 3.7e-18 65.4 0.0 1e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EPE26121.1 - 2.3e-08 34.0 1.0 2.1e-06 27.7 0.0 3.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPE26121.1 - 2.9e-06 27.2 0.1 9.9e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EPE26121.1 - 0.00072 19.1 0.0 0.0018 17.8 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EPE26121.1 - 0.22 11.4 0.0 0.22 11.4 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain ATG22 PF11700.3 EPE26122.1 - 1.1e-130 436.3 28.7 1.3e-130 436.1 19.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like BAR_2 PF10455.4 EPE26123.1 - 3.1e-63 213.3 0.3 4.5e-63 212.8 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EPE26123.1 - 2.8e-19 69.5 1.4 1.5e-18 67.1 1.0 1.9 1 1 0 1 1 1 1 BAR domain Tox-GHH2 PF15635.1 EPE26123.1 - 0.011 16.1 0.2 0.082 13.2 0.0 2.3 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 Apolipoprotein PF01442.13 EPE26123.1 - 0.11 12.0 6.8 0.029 13.8 0.5 2.4 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain YdjC PF04794.7 EPE26123.1 - 0.72 9.2 3.8 0.25 10.7 0.2 1.9 2 1 1 3 3 3 0 YdjC-like protein DUF619 PF04768.8 EPE26124.1 - 9.5e-51 171.5 0.0 1.7e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF619) DnaJ PF00226.26 EPE26125.1 - 5.5e-22 77.2 1.4 1.2e-21 76.1 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EPE26125.1 - 7.2e-18 64.2 0.0 2.6e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EPE26125.1 - 2.1e-11 43.7 17.3 3.5e-11 42.9 12.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EPE26125.1 - 0.043 13.5 5.7 1.7 8.3 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Fungal_trans PF04082.13 EPE26126.1 - 2.3e-11 43.0 0.0 3.8e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE26126.1 - 1.2e-08 34.7 8.0 2.3e-08 33.8 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.21 EPE26127.1 - 7.1e-46 155.8 0.1 9e-46 155.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EPE26127.1 - 1.8e-13 49.4 1.9 3.9e-13 48.3 1.3 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal WD40 PF00400.27 EPE26128.1 - 0.12 12.2 0.1 0.76 9.7 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat NatB_MDM20 PF09797.4 EPE26129.1 - 1.1e-63 215.1 0.6 1.1e-63 215.1 0.4 1.6 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF3826 PF12875.2 EPE26129.1 - 0.026 14.2 0.2 0.056 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) TerY-C PF15616.1 EPE26129.1 - 0.041 13.8 0.1 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain 2OG-Fe_Oxy_2 PF10014.4 EPE26130.1 - 0.042 13.2 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe dioxygenase 2OG-FeII_Oxy_3 PF13640.1 EPE26130.1 - 0.06 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-C3HC4_2 PF13923.1 EPE26131.1 - 4.4e-06 26.6 12.5 4.4e-06 26.6 8.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE26131.1 - 4.7e-06 26.1 10.7 1e-05 25.1 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPE26131.1 - 8.8e-06 25.5 12.2 8.8e-06 25.5 8.5 1.8 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EPE26131.1 - 7.5e-05 22.4 15.3 7.5e-05 22.4 10.6 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPE26131.1 - 0.00013 21.5 15.9 0.00017 21.2 7.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE26131.1 - 0.00014 21.4 9.9 0.00014 21.4 6.9 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPE26131.1 - 0.0028 17.3 4.7 0.0059 16.2 3.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger UPF0547 PF10571.4 EPE26131.1 - 0.025 14.2 5.7 0.23 11.1 0.7 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_6 PF14835.1 EPE26131.1 - 0.051 13.3 7.5 0.12 12.1 5.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zinc_ribbon_2 PF13240.1 EPE26131.1 - 0.76 9.3 8.3 6.2 6.4 0.1 3.5 2 1 2 4 4 4 0 zinc-ribbon domain DZR PF12773.2 EPE26131.1 - 2.6 7.9 14.1 2.8 7.8 0.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon Ilm1 PF10311.4 EPE26132.1 - 1.5e-51 174.1 3.6 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF1049 PF06305.6 EPE26132.1 - 0.66 9.4 0.1 0.66 9.4 0.1 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Prenyltrans PF00432.16 EPE26133.1 - 2.7e-36 122.8 12.6 2.9e-08 33.1 1.2 6.9 6 2 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPE26133.1 - 2.4e-24 85.8 0.0 8.1e-14 51.9 0.0 4.4 1 1 4 5 5 5 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPE26133.1 - 8.2e-08 32.2 0.0 0.00053 19.9 0.0 3.9 2 1 2 4 4 4 3 Prenyltransferase-like SIS PF01380.17 EPE26134.1 - 8.5e-55 183.9 0.1 4.6e-30 103.9 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EPE26134.1 - 1e-27 96.8 0.0 1.9e-18 66.3 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EPE26134.1 - 1.2e-19 70.5 0.0 2.7e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EPE26134.1 - 3e-11 43.1 0.0 6.6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EPE26134.1 - 1.8e-06 26.8 0.0 3.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EPE26134.1 - 0.054 13.2 0.0 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 SIS domain AAA PF00004.24 EPE26135.1 - 5e-43 146.4 0.0 8.7e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE26135.1 - 3.9e-08 33.4 0.1 4.1e-06 26.9 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EPE26135.1 - 1.9e-06 27.6 0.1 3.7e-05 23.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPE26135.1 - 2.3e-06 27.6 0.0 7.7e-06 25.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EPE26135.1 - 2.8e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EPE26135.1 - 7.5e-06 25.1 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EPE26135.1 - 0.00021 20.3 0.0 0.00062 18.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EPE26135.1 - 0.00032 20.3 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EPE26135.1 - 0.00062 20.5 0.5 0.0023 18.7 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPE26135.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPE26135.1 - 0.0014 18.5 0.0 0.0063 16.4 0.0 2.1 3 0 0 3 3 2 1 AAA domain DUF4200 PF13863.1 EPE26135.1 - 0.0015 18.4 1.0 0.0035 17.2 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) TIP49 PF06068.8 EPE26135.1 - 0.0016 17.2 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 EPE26135.1 - 0.0017 18.6 0.1 0.0081 16.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EPE26135.1 - 0.0024 17.3 0.0 0.0053 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EPE26135.1 - 0.0035 16.5 0.0 0.0065 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EPE26135.1 - 0.005 17.0 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EPE26135.1 - 0.0057 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EPE26135.1 - 0.0074 15.7 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EPE26135.1 - 0.0079 15.6 0.1 0.046 13.1 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EPE26135.1 - 0.0092 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EPE26135.1 - 0.019 14.5 0.1 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EPE26135.1 - 0.019 14.0 0.7 0.11 11.6 0.0 2.4 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 EPE26135.1 - 0.023 14.7 0.0 0.064 13.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.10 EPE26135.1 - 0.023 14.5 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EPE26135.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EPE26135.1 - 0.029 14.0 0.0 0.14 11.8 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase AAA_11 PF13086.1 EPE26135.1 - 0.03 13.9 0.3 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EPE26135.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EPE26135.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain HAUS-augmin3 PF14932.1 EPE26135.1 - 0.046 12.8 0.2 0.066 12.3 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Tropomyosin_1 PF12718.2 EPE26135.1 - 0.047 13.5 1.0 0.095 12.5 0.7 1.4 1 0 0 1 1 1 0 Tropomyosin like UPF0079 PF02367.12 EPE26135.1 - 0.05 13.2 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EPE26135.1 - 0.051 13.9 3.4 3.8 7.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EPE26135.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EPE26135.1 - 0.092 12.1 0.1 1.4 8.2 0.0 2.5 3 0 0 3 3 2 0 Thymidylate kinase eIF-1a PF01176.14 EPE26135.1 - 0.1 12.0 0.1 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Parvo_NS1 PF01057.12 EPE26135.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IncA PF04156.9 EPE26135.1 - 0.37 10.3 2.4 0.71 9.4 1.6 1.4 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EPE26135.1 - 0.45 10.0 3.8 2.9 7.4 1.3 2.7 2 0 0 2 2 2 0 Septum formation initiator Enolase_C PF00113.17 EPE26136.1 - 1.8e-150 499.8 0.0 2.4e-150 499.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EPE26136.1 - 9.9e-59 197.0 0.6 1.8e-58 196.1 0.4 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EPE26136.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Enolase C-terminal domain-like MR_MLE PF01188.16 EPE26136.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain eIF3_subunit PF08597.5 EPE26137.1 - 8.2e-68 228.5 28.5 9.3e-68 228.4 19.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit tRNA-synt_1c PF00749.16 EPE26137.1 - 0.73 8.4 6.1 0.1 11.2 1.4 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain FNIP_N PF14636.1 EPE26137.1 - 0.79 10.2 8.9 0.26 11.7 2.9 2.3 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Nop53 PF07767.6 EPE26137.1 - 4.6 6.1 27.1 1.3 7.8 12.3 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Glyco_hydro_3 PF00933.16 EPE26138.1 - 2.1e-90 302.7 0.0 4e-90 301.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE26138.1 - 2.1e-59 200.7 3.6 7.9e-59 198.9 2.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE26138.1 - 1.9e-14 53.3 0.0 5.2e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain tRNA-synt_1b PF00579.20 EPE26144.1 - 1.2e-55 188.6 0.0 1.6e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Peptidase_M3 PF01432.15 EPE26145.1 - 2.2e-121 406.1 0.0 3.5e-121 405.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EPE26145.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like DNA_pol3_delt_C PF14840.1 EPE26145.1 - 0.05 13.7 0.1 0.73 9.9 0.0 2.6 2 0 0 2 2 2 0 Processivity clamp loader gamma complex DNA pol III C-term ISG65-75 PF11727.3 EPE26145.1 - 0.16 10.9 1.0 0.28 10.1 0.7 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein ApoO PF09769.4 EPE26146.1 - 4.6e-51 172.6 1.7 3.2e-49 166.6 0.1 2.1 2 0 0 2 2 2 2 Apolipoprotein O DUF3084 PF11283.3 EPE26146.1 - 0.053 13.3 0.0 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) Pyr_redox_2 PF07992.9 EPE26148.1 - 7e-21 75.0 0.0 1.1e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE26148.1 - 1.5e-09 38.1 0.0 5.4e-08 33.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_76 PF03663.9 EPE26149.1 - 6.7e-39 134.3 16.0 1.9e-38 132.8 11.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 EPE26149.1 - 0.0093 14.2 0.2 0.031 12.5 0.1 1.7 1 1 1 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) WD40 PF00400.27 EPE26150.1 - 4.5e-66 216.5 20.9 2.6e-13 49.2 0.2 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EPE26150.1 - 8.5e-09 35.4 0.0 0.0045 16.7 0.0 3.4 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPE26150.1 - 3.6e-08 32.0 1.8 0.0014 16.9 0.2 3.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPE26150.1 - 2.1e-05 23.4 0.1 0.049 12.3 0.0 4.0 3 2 1 4 4 4 1 Nup133 N terminal like DUF1513 PF07433.6 EPE26150.1 - 3.8e-05 22.7 1.5 0.48 9.2 0.0 3.9 2 2 2 4 4 4 2 Protein of unknown function (DUF1513) PD40 PF07676.7 EPE26150.1 - 0.00016 21.2 1.1 1.5 8.5 0.1 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EPE26150.1 - 0.0011 18.4 1.4 1.6 8.1 0.1 3.1 2 1 0 2 2 2 2 PQQ-like domain Coatomer_WDAD PF04053.9 EPE26150.1 - 0.0042 15.9 0.0 4.6 5.9 0.0 3.0 1 1 1 3 3 3 1 Coatomer WD associated region DUF3312 PF11768.3 EPE26150.1 - 0.011 14.0 0.0 0.02 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 EPE26150.1 - 0.017 13.4 0.0 5.5 5.1 0.0 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain Nbas_N PF15492.1 EPE26150.1 - 0.038 13.0 0.1 4.8 6.1 0.0 2.8 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal GspH PF12019.3 EPE26150.1 - 0.04 14.0 0.1 17 5.6 0.0 3.2 1 1 2 3 3 3 0 Type II transport protein GspH IKI3 PF04762.7 EPE26150.1 - 0.16 9.7 0.0 0.39 8.4 0.0 1.6 2 0 0 2 2 2 0 IKI3 family PQQ_3 PF13570.1 EPE26150.1 - 0.51 10.6 6.9 8.3 6.8 0.4 4.1 2 2 0 2 2 2 0 PQQ-like domain CDC45 PF02724.9 EPE26150.1 - 3.6 5.5 5.0 5 5.0 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Exo_endo_phos PF03372.18 EPE26151.1 - 2.3e-17 63.7 0.0 3.6e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF2_N PF00176.18 EPE26152.1 - 2.4e-37 128.3 0.0 9.1e-34 116.6 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE26152.1 - 2.6e-05 23.9 0.0 0.00025 20.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HET PF06985.6 EPE26153.1 - 3.7e-22 78.9 0.3 9.9e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FAM60A PF15396.1 EPE26153.1 - 0.03 14.0 0.1 0.03 14.0 0.1 2.0 2 0 0 2 2 2 0 Protein Family FAM60A Glyco_hydro_62 PF03664.8 EPE26154.1 - 3e-70 236.4 2.0 3.4e-70 236.2 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 HlyIII PF03006.15 EPE26155.1 - 6.5e-52 176.1 20.0 8.1e-52 175.8 13.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related TRAM_LAG1_CLN8 PF03798.11 EPE26156.1 - 1.7e-41 141.9 17.2 1.7e-41 141.9 11.9 2.0 2 0 0 2 2 2 2 TLC domain BTB PF00651.26 EPE26158.1 - 0.0011 18.9 2.6 0.16 11.9 0.1 2.8 2 1 1 3 3 3 2 BTB/POZ domain DUF2953 PF11167.3 EPE26158.1 - 0.14 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) DUF4293 PF14126.1 EPE26161.1 - 0.025 14.4 0.1 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF639 PF04842.7 EPE26163.1 - 0.092 10.8 0.1 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) YrhK PF14145.1 EPE26163.1 - 0.61 9.7 5.2 13 5.5 0.0 3.4 3 0 0 3 3 3 0 YrhK-like protein Mad3_BUB1_I PF08311.7 EPE26164.1 - 9.9e-43 144.9 0.1 4.3e-42 142.8 0.0 2.1 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EPE26164.1 - 5.5e-14 51.9 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE26164.1 - 3.7e-08 32.7 0.0 9.7e-08 31.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 EPE26164.1 - 0.00067 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 BTB PF00651.26 EPE26165.1 - 8.8e-07 28.8 0.1 1.2e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain RasGEF_N PF00618.15 EPE26166.1 - 0.0079 16.2 0.1 0.016 15.2 0.0 1.6 2 0 0 2 2 2 1 RasGEF N-terminal motif Tubulin_C PF03953.12 EPE26166.1 - 0.043 13.8 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin C-terminal domain Aegerolysin PF06355.8 EPE26167.1 - 5.9e-11 42.3 0.5 7e-11 42.1 0.3 1.1 1 0 0 1 1 1 1 Aegerolysin DUF1902 PF08972.6 EPE26168.1 - 0.013 15.0 0.2 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) CwfJ_C_1 PF04677.10 EPE26169.1 - 4.6e-27 94.0 0.0 7.2e-26 90.2 0.0 2.4 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EPE26169.1 - 1.3e-24 86.5 0.1 2.8e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.18 EPE26169.1 - 0.046 14.2 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 HIT domain K_oxygenase PF13434.1 EPE26169.1 - 0.2 10.5 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Cyclin_N PF00134.18 EPE26170.1 - 8.6e-13 47.9 1.7 1.1e-11 44.3 0.1 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain DRIM PF07539.7 EPE26171.1 - 1.4e-42 144.4 0.3 4.4e-42 142.8 0.2 2.0 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT_2 PF13646.1 EPE26171.1 - 0.0014 18.8 8.3 0.7 10.2 0.0 6.5 6 0 0 6 6 6 2 HEAT repeats HEAT PF02985.17 EPE26171.1 - 0.68 10.1 7.4 1.3 9.2 0.0 5.4 6 0 0 6 6 6 0 HEAT repeat zf-DNL PF05180.7 EPE26172.1 - 2.5e-28 97.5 0.6 3.8e-28 97.0 0.4 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 EPE26172.1 - 0.02 14.3 0.3 0.037 13.5 0.2 1.4 1 0 0 1 1 1 0 CSL zinc finger Elf1 PF05129.8 EPE26172.1 - 0.071 12.8 0.3 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like TFIIS_C PF01096.13 EPE26172.1 - 0.08 12.5 0.7 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Cullin PF00888.17 EPE26173.1 - 8.3e-133 443.9 8.6 1.2e-132 443.4 5.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EPE26173.1 - 1.4e-24 85.6 2.3 4.5e-24 84.0 1.6 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain MT0933_antitox PF14013.1 EPE26174.1 - 5.4 7.2 7.4 3.2 7.9 2.0 2.6 2 1 0 2 2 2 0 MT0933-like antitoxin protein DNA_pol_phi PF04931.8 EPE26175.1 - 1.1e-54 185.5 42.7 3.7e-54 183.7 29.6 1.8 1 1 0 1 1 1 1 DNA polymerase phi RRN3 PF05327.6 EPE26175.1 - 0.24 9.4 15.7 0.54 8.2 10.9 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1664 PF07889.7 EPE26176.1 - 0.013 15.3 2.2 0.77 9.5 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 EPE26176.1 - 0.034 12.8 10.3 0.016 13.8 0.8 2.8 3 1 0 3 3 3 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EPE26176.1 - 0.047 13.4 9.7 8.3 6.2 0.4 4.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding INT_SG_DDX_CT_C PF15300.1 EPE26176.1 - 0.051 13.0 0.9 2.6 7.5 0.1 3.6 4 0 0 4 4 4 0 INTS6/SAGE1/DDX26B/CT45 C-terminus SF-assemblin PF06705.6 EPE26176.1 - 0.088 11.9 4.5 0.081 12.0 0.2 2.4 2 0 0 2 2 2 0 SF-assemblin/beta giardin APG17 PF04108.7 EPE26176.1 - 0.93 8.2 9.5 0.031 13.0 1.8 1.9 2 0 0 2 2 2 0 Autophagy protein Apg17 DUF812 PF05667.6 EPE26176.1 - 7 5.0 12.6 0.15 10.5 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) NACHT PF05729.7 EPE26177.1 - 2.6e-07 30.4 0.0 5.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EPE26177.1 - 0.00037 20.6 0.0 0.0068 16.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain PGAP1 PF07819.8 EPE26177.1 - 0.0061 16.1 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EPE26177.1 - 0.012 15.5 0.0 0.038 13.8 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF829 PF05705.9 EPE26177.1 - 0.016 14.9 0.1 0.062 12.9 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) AAA_16 PF13191.1 EPE26177.1 - 0.017 15.1 0.0 0.054 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DUF676 PF05057.9 EPE26177.1 - 0.025 13.8 0.0 0.055 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RNA_helicase PF00910.17 EPE26177.1 - 0.12 12.5 0.2 1.5 9.0 0.0 3.0 4 0 0 4 4 4 0 RNA helicase KAP_NTPase PF07693.9 EPE26177.1 - 0.12 11.2 1.0 2 7.3 0.3 2.2 1 1 0 2 2 2 0 KAP family P-loop domain Peptidase_M56 PF05569.6 EPE26178.1 - 0.0034 16.4 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 Pex14_N PF04695.8 EPE26178.1 - 0.0048 16.9 0.3 0.0099 15.9 0.2 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Rifin_STEVOR PF02009.11 EPE26178.1 - 0.0073 15.9 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family Podoplanin PF05808.6 EPE26178.1 - 0.017 14.7 0.4 0.029 13.9 0.3 1.4 1 0 0 1 1 1 0 Podoplanin DUF4328 PF14219.1 EPE26178.1 - 0.019 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) 5TM-5TMR_LYT PF07694.7 EPE26178.1 - 0.036 13.4 0.1 0.076 12.3 0.1 1.5 1 0 0 1 1 1 0 5TMR of 5TMR-LYT TMEM154 PF15102.1 EPE26178.1 - 0.038 13.6 0.4 0.069 12.8 0.3 1.3 1 0 0 1 1 1 0 TMEM154 protein family MLANA PF14991.1 EPE26178.1 - 0.062 13.3 1.1 0.13 12.2 0.3 1.9 2 1 0 2 2 2 0 Protein melan-A EphA2_TM PF14575.1 EPE26178.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Sensor PF13796.1 EPE26178.1 - 0.12 11.9 2.0 0.28 10.7 1.4 1.5 1 0 0 1 1 1 0 Putative sensor DUF1576 PF07613.6 EPE26178.1 - 0.21 11.0 2.8 0.35 10.3 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) Plasmodium_Vir PF05795.6 EPE26178.1 - 0.28 10.3 0.0 0.36 9.9 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Thi4 PF01946.12 EPE26179.1 - 6.3e-107 355.8 0.0 7.5e-107 355.6 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EPE26179.1 - 1.6e-07 30.5 0.2 8.4e-07 28.2 0.3 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE26179.1 - 1.8e-05 23.8 0.4 5.1e-05 22.3 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPE26179.1 - 8.6e-05 22.4 0.2 0.00026 20.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPE26179.1 - 0.0002 21.1 0.4 0.00093 19.0 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EPE26179.1 - 0.002 17.0 1.9 0.091 11.5 0.2 2.8 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 EPE26179.1 - 0.0021 18.1 0.2 0.0029 17.7 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE26179.1 - 0.0036 17.1 0.3 0.012 15.5 0.3 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPE26179.1 - 0.08 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EPE26179.1 - 0.11 11.0 0.2 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.1 EPE26179.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) AP_endonuc_2 PF01261.19 EPE26180.1 - 4.9e-31 107.6 0.1 6.8e-31 107.2 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Pectinesterase PF01095.14 EPE26181.1 - 0.049 12.2 0.3 0.053 12.0 0.2 1.0 1 0 0 1 1 1 0 Pectinesterase RED_N PF07808.8 EPE26183.1 - 0.0017 17.6 1.6 0.0033 16.6 1.1 1.5 1 0 0 1 1 1 1 RED-like protein N-terminal region zf-UBR PF02207.15 EPE26184.1 - 4.4e-18 64.7 13.2 1.1e-17 63.4 9.1 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EPE26184.1 - 7.4e-06 25.6 0.3 1.5e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 EPE26184.1 - 0.0016 18.2 1.8 0.0016 18.2 1.3 5.1 5 1 1 6 6 6 1 Ring finger domain CAP_N PF01213.14 EPE26184.1 - 5.5 6.1 5.8 2.7 7.2 2.1 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal UCR_UQCRX_QCR9 PF05365.7 EPE26185.1 - 1.2e-25 88.8 1.4 1.9e-25 88.2 0.9 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 EPE26186.1 - 9.4e-13 47.4 2.7 1.9e-12 46.5 1.9 1.5 1 0 0 1 1 1 1 Mago binding Peptidase_A21 PF03566.8 EPE26186.1 - 0.22 9.5 2.2 0.25 9.3 1.6 1.1 1 0 0 1 1 1 0 Peptidase family A21 NAM-associated PF14303.1 EPE26186.1 - 0.62 10.3 12.1 0.8 10.0 8.4 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF3827 PF12877.2 EPE26186.1 - 1.3 7.0 5.8 1.5 6.8 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Dsh_C PF12316.3 EPE26186.1 - 2.9 7.9 9.6 3.7 7.5 5.6 1.7 1 1 1 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal eIF3_subunit PF08597.5 EPE26186.1 - 3.5 7.1 18.9 4.3 6.8 13.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4407 PF14362.1 EPE26186.1 - 3.6 6.4 8.4 4.1 6.2 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spore_coat_CotO PF14153.1 EPE26186.1 - 5.3 6.4 10.9 7.8 5.8 7.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO IU_nuc_hydro PF01156.14 EPE26187.1 - 5.8e-85 285.2 0.0 6.8e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF3129 PF11327.3 EPE26188.1 - 1e-68 230.7 17.2 1.4e-68 230.3 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) AMP-binding PF00501.23 EPE26189.1 - 3e-28 98.3 0.0 5.9e-28 97.4 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme CSTF2_hinge PF14327.1 EPE26190.1 - 3.7e-30 103.8 2.0 3.7e-30 103.8 1.4 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EPE26190.1 - 1.7e-20 72.4 0.0 2.5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE26190.1 - 8.2e-16 57.7 0.0 1.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EPE26190.1 - 2e-08 33.3 10.1 3.3e-08 32.6 5.1 2.3 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 EPE26190.1 - 3.6e-08 33.1 0.0 5.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Band_7 PF01145.20 EPE26191.1 - 1.2e-23 83.8 1.7 1.7e-23 83.4 1.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S9 PF00326.16 EPE26193.1 - 9e-50 168.8 0.9 9e-50 168.8 0.6 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE26193.1 - 1.7e-10 40.8 0.1 3.3e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EPE26193.1 - 1.8e-07 29.9 0.2 4e-05 22.2 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 EPE26193.1 - 0.00012 21.9 0.3 0.00048 20.0 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EPE26193.1 - 0.031 12.9 0.3 0.046 12.4 0.2 1.1 1 0 0 1 1 1 0 Carboxylesterase family Ank PF00023.25 EPE26194.1 - 1.2e-15 56.4 0.0 0.071 12.9 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 EPE26194.1 - 1.1e-13 51.3 0.0 1.1e-05 25.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE26194.1 - 1.2e-12 47.9 0.0 0.0092 16.4 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE26194.1 - 2.8e-11 42.5 0.0 0.28 11.5 0.0 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EPE26194.1 - 6.2e-11 42.1 0.0 0.01 16.0 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeats (many copies) TPT PF03151.11 EPE26195.1 - 1.9e-33 115.2 9.5 1.9e-33 115.2 6.6 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EPE26195.1 - 1.9e-05 23.7 13.2 1.9e-05 23.7 9.2 1.7 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 EPE26195.1 - 0.0099 15.9 1.9 0.0099 15.9 1.3 3.0 3 0 0 3 3 3 2 EamA-like transporter family HET PF06985.6 EPE26197.1 - 9.7e-31 106.7 1.2 2.2e-30 105.6 0.8 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TMEM52 PF14979.1 EPE26197.1 - 0.029 14.2 1.2 11 5.9 0.4 2.8 2 0 0 2 2 2 0 Transmembrane 52 SWI-SNF_Ssr4 PF08549.5 EPE26198.1 - 8.3e-188 625.8 5.0 1e-187 625.5 3.5 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) 6PGD PF00393.14 EPE26200.1 - 2.1e-132 440.7 0.0 2.6e-132 440.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EPE26200.1 - 1.1e-50 171.6 0.0 1.6e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EPE26200.1 - 0.016 15.2 0.0 0.069 13.2 0.0 2.1 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.14 EPE26200.1 - 0.059 11.9 0.0 0.089 11.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoglycerate kinase DUF401 PF04165.7 EPE26200.1 - 0.21 10.5 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF401) RRM_1 PF00076.17 EPE26201.1 - 2e-17 62.6 0.0 3.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE26201.1 - 1.7e-09 37.5 0.0 3.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE26201.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EPE26201.1 - 0.1 12.1 0.6 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Abhydrolase_5 PF12695.2 EPE26202.1 - 9.9e-10 38.3 0.0 2e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE26202.1 - 6.9e-09 35.9 0.6 9.2e-09 35.5 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EPE26202.1 - 7.7e-09 34.4 0.0 6.8e-06 24.8 0.0 3.0 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EPE26202.1 - 2.3e-06 26.9 0.1 2.1e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EPE26202.1 - 5.8e-06 26.1 0.0 1.5e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EPE26202.1 - 0.00065 19.2 0.0 0.0025 17.2 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EPE26202.1 - 0.0007 18.9 0.0 0.0013 18.0 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Glyco_hydro_15 PF00723.16 EPE26203.1 - 1.6e-54 185.1 0.0 4.8e-52 177.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 CorA PF01544.13 EPE26204.1 - 4.1e-07 29.3 0.1 4.1e-07 29.3 0.1 3.1 3 0 0 3 3 3 2 CorA-like Mg2+ transporter protein PI-PLC-X PF00388.14 EPE26205.1 - 0.043 13.2 0.0 0.092 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain K1 PF02960.9 EPE26205.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 K1 glycoprotein PEHE PF15275.1 EPE26206.1 - 0.87 10.0 13.4 3 8.3 2.6 3.1 2 1 1 3 3 3 0 PEHE domain DUF1510 PF07423.6 EPE26207.1 - 0.053 12.8 5.4 0.087 12.1 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Prominin PF05478.6 EPE26208.1 - 0.031 11.8 0.1 0.032 11.7 0.1 1.0 1 0 0 1 1 1 0 Prominin RdRP PF05183.7 EPE26210.1 - 4.1e-166 554.0 0.0 5.3e-166 553.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 EPE26210.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PD40 PF07676.7 EPE26211.1 - 1.7e-05 24.3 0.2 0.012 15.3 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat WD40 PF00400.27 EPE26211.1 - 6.3e-05 22.6 0.0 0.55 10.2 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF2583 PF10762.4 EPE26211.1 - 0.034 14.2 0.2 0.069 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) U-box PF04564.10 EPE26212.1 - 0.027 14.4 0.1 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 U-box domain DUF2985 PF11204.3 EPE26213.1 - 4.5e-33 112.8 3.1 4.5e-33 112.8 2.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF2567 PF10821.3 EPE26213.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) Sld5 PF05916.6 EPE26214.1 - 9.6e-08 32.2 0.3 1.7e-07 31.5 0.2 1.4 1 0 0 1 1 1 1 GINS complex protein DUF896 PF05979.7 EPE26214.1 - 0.063 12.8 0.3 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) SNase PF00565.12 EPE26215.1 - 1.2e-05 25.4 0.0 7.9e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Staphylococcal nuclease homologue HrpJ PF07201.6 EPE26216.1 - 0.087 12.8 1.4 0.12 12.3 1.0 1.1 1 0 0 1 1 1 0 HrpJ-like domain Rhodanese PF00581.15 EPE26218.1 - 5.7e-11 42.7 0.0 1.4e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Sugar_tr PF00083.19 EPE26220.1 - 3e-81 273.3 21.4 3.8e-81 272.9 14.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE26220.1 - 8e-23 80.7 24.3 8e-23 80.7 16.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE26220.1 - 7.2e-07 27.7 1.2 7.2e-07 27.7 0.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EPE26220.1 - 0.0013 17.2 7.2 0.0013 17.2 5.0 3.1 2 2 0 2 2 2 2 MFS/sugar transport protein OAD_gamma PF04277.8 EPE26220.1 - 3.4 8.1 5.3 27 5.2 0.0 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain CENP-B_dimeris PF09026.5 EPE26222.1 - 0.044 14.0 2.1 0.044 14.0 1.5 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SDA1 PF05285.7 EPE26222.1 - 1.3 8.2 10.4 1.6 7.9 7.2 1.1 1 0 0 1 1 1 0 SDA1 AF-4 PF05110.8 EPE26222.1 - 2.5 5.8 7.3 2.8 5.7 5.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Indigoidine_A PF04227.7 EPE26224.1 - 2.5e-114 381.4 0.0 4.4e-114 380.6 0.0 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EPE26224.1 - 3.2e-23 82.3 1.1 9.6e-22 77.4 0.8 2.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase POX PF07526.6 EPE26224.1 - 0.27 11.4 1.3 0.91 9.7 0.8 1.8 2 0 0 2 2 2 0 Associated with HOX adh_short PF00106.20 EPE26226.1 - 1.4e-25 90.1 1.9 7.5e-25 87.7 1.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE26226.1 - 1.8e-12 47.5 0.0 2.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE26226.1 - 1.5e-08 34.5 2.4 7e-07 29.0 1.7 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPE26226.1 - 0.00016 21.7 0.0 0.00058 19.9 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE26226.1 - 0.00053 19.4 0.1 0.0012 18.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPE26226.1 - 0.0014 17.5 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 EPE26226.1 - 0.029 14.3 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EPE26226.1 - 0.055 13.0 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3Beta_HSD PF01073.14 EPE26226.1 - 0.059 12.0 0.1 0.13 10.9 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family FtsJ PF01728.14 EPE26226.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Polysacc_synt_2 PF02719.10 EPE26226.1 - 0.52 9.1 4.6 0.2 10.5 1.3 1.9 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein DUF2514 PF10721.4 EPE26227.1 - 0.13 11.9 6.8 0.17 11.5 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Ribosomal_S8e PF01201.17 EPE26227.1 - 0.89 9.6 4.5 1.1 9.3 3.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S8e DUF4192 PF13830.1 EPE26227.1 - 1.7 8.1 3.8 2.4 7.7 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) TBCA PF02970.11 EPE26229.1 - 2e-21 75.8 8.2 4.7e-21 74.6 5.7 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor A TEBP_beta PF07404.6 EPE26229.1 - 0.0055 15.8 0.4 0.0055 15.8 0.3 1.0 1 0 0 1 1 1 1 Telomere-binding protein beta subunit (TEBP beta) IncA PF04156.9 EPE26229.1 - 0.015 14.8 2.8 0.018 14.6 1.9 1.1 1 0 0 1 1 1 0 IncA protein Dynamitin PF04912.9 EPE26229.1 - 0.018 13.8 1.8 0.044 12.6 1.2 1.6 1 1 0 1 1 1 0 Dynamitin Toxin_39 PF15500.1 EPE26229.1 - 0.029 14.4 1.6 0.036 14.1 0.8 1.5 1 1 1 2 2 2 0 Putative RNase-like toxin CALCOCO1 PF07888.6 EPE26229.1 - 0.14 10.4 3.7 0.16 10.2 2.5 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Herpes_UL14 PF03580.9 EPE26229.1 - 0.16 11.7 3.5 0.21 11.3 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL14-like protein DUF2721 PF11026.3 EPE26229.1 - 0.19 11.3 1.0 2.9 7.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Fmp27_WPPW PF10359.4 EPE26229.1 - 0.2 10.0 2.4 0.21 9.9 1.7 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc24 PF08286.6 EPE26229.1 - 0.24 11.0 3.7 0.52 10.0 1.5 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 KfrA_N PF11740.3 EPE26229.1 - 0.34 11.3 10.6 1.7 9.0 1.4 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term APG6 PF04111.7 EPE26229.1 - 0.5 9.3 3.8 0.57 9.1 2.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Strabismus PF06638.6 EPE26229.1 - 0.58 8.3 2.6 0.72 8.1 1.8 1.0 1 0 0 1 1 1 0 Strabismus protein TMCO5 PF14992.1 EPE26229.1 - 0.73 8.9 4.4 0.83 8.7 3.1 1.1 1 0 0 1 1 1 0 TMCO5 family DUF4164 PF13747.1 EPE26229.1 - 2.2 8.4 10.7 4.6 7.4 0.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF4407 PF14362.1 EPE26229.1 - 3.1 6.6 6.1 3.6 6.4 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) THOC7 PF05615.8 EPE26230.1 - 5.8e-42 143.2 10.0 5.8e-42 143.2 6.9 1.7 2 0 0 2 2 2 1 Tho complex subunit 7 zf-C4H2 PF10146.4 EPE26230.1 - 2.8 7.9 13.0 0.23 11.4 2.7 2.6 1 1 2 3 3 3 0 Zinc finger-containing protein Elongin_A PF06881.6 EPE26231.1 - 1.5e-19 70.3 1.4 1.5e-19 70.3 0.9 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A NOA36 PF06524.7 EPE26231.1 - 1.8 7.7 4.4 2.6 7.2 3.1 1.1 1 0 0 1 1 1 0 NOA36 protein ubiquitin PF00240.18 EPE26232.1 - 6.5e-24 83.1 0.1 7.2e-24 82.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPE26232.1 - 1.4e-15 56.6 0.1 1.6e-15 56.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPE26232.1 - 0.00013 22.1 0.0 0.00025 21.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain CTDII PF01556.13 EPE26232.1 - 0.081 12.8 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 DnaJ C terminal domain HMA PF00403.21 EPE26232.1 - 0.14 12.2 0.3 0.2 11.8 0.2 1.2 1 0 0 1 1 1 0 Heavy-metal-associated domain MFS_1 PF07690.11 EPE26233.1 - 4.2e-33 114.5 24.7 4.2e-33 114.5 17.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.8 EPE26234.1 - 1.1e-80 271.1 2.2 1.3e-80 270.9 1.5 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Thioredoxin PF00085.15 EPE26235.1 - 3.9e-07 29.7 0.2 3.6e-06 26.5 0.2 2.1 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.6 EPE26236.1 - 0.021 14.6 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin PF00085.15 EPE26236.1 - 0.036 13.7 0.0 0.085 12.5 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin Redoxin PF08534.5 EPE26237.1 - 1.8e-29 102.1 0.0 2e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EPE26237.1 - 5.2e-07 29.3 0.0 6.2e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Mito_fiss_reg PF05308.6 EPE26238.1 - 6.8 5.9 8.2 4.4 6.5 1.6 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator AA_permease PF00324.16 EPE26239.1 - 1.3e-133 445.8 44.0 1.6e-133 445.5 30.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE26239.1 - 1.7e-35 122.3 46.5 2.2e-35 122.0 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease DOG1 PF14144.1 EPE26240.1 - 0.051 13.6 0.4 0.18 11.8 0.1 2.2 2 0 0 2 2 2 0 Seed dormancy control Epimerase PF01370.16 EPE26242.1 - 5.6e-15 55.4 0.0 8.9e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE26242.1 - 1.7e-07 31.3 0.1 1.2e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE26242.1 - 2.3e-05 23.2 0.0 5.6e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPE26242.1 - 2.4e-05 23.4 0.0 3.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EPE26242.1 - 0.0019 17.1 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPE26242.1 - 0.037 13.9 0.2 0.18 11.7 0.0 2.2 2 1 0 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.11 EPE26243.1 - 1.4e-41 142.4 17.3 1.4e-41 142.4 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26243.1 - 1.8e-15 56.4 1.4 1.8e-15 56.4 1.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter BTB PF00651.26 EPE26244.1 - 6.2e-05 22.9 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain GBV-C_env PF12786.2 EPE26244.1 - 0.052 12.0 0.0 0.079 11.4 0.0 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope zf-C3HC4_4 PF15227.1 EPE26244.1 - 0.31 10.9 3.6 3.9 7.4 0.9 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING adh_short PF00106.20 EPE26245.1 - 1.3e-15 57.6 0.0 2.2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE26245.1 - 2.7e-06 27.1 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE26245.1 - 0.00022 20.7 0.0 0.00036 20.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EPE26245.1 - 0.0071 16.1 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPE26245.1 - 0.0072 16.3 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Amidoligase_2 PF12224.3 EPE26247.1 - 2.7e-10 40.2 0.1 9.1e-05 22.1 0.0 2.7 3 0 0 3 3 3 2 Putative amidoligase enzyme MFS_1 PF07690.11 EPE26248.1 - 1.9e-34 118.9 41.8 2.7e-32 111.8 29.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26248.1 - 2.5e-09 36.2 11.2 2.5e-09 36.2 7.8 3.3 2 2 1 3 3 3 1 Sugar (and other) transporter Sulfotransfer_3 PF13469.1 EPE26249.1 - 0.037 14.9 0.5 0.36 11.7 0.1 2.1 1 1 1 2 2 2 0 Sulfotransferase family DUF456 PF04306.8 EPE26250.1 - 0.98 9.4 10.2 0.24 11.4 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF456) ketoacyl-synt PF00109.21 EPE26251.1 - 1.5e-74 250.6 0.0 2.8e-74 249.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EPE26251.1 - 1.5e-59 200.7 0.1 5.9e-59 198.7 0.0 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EPE26251.1 - 2.4e-51 174.9 0.0 3.7e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EPE26251.1 - 4.8e-46 157.2 0.0 9.9e-46 156.2 0.0 1.5 2 0 0 2 2 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EPE26251.1 - 1.2e-42 145.6 0.6 8.4e-42 142.9 0.0 2.6 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPE26251.1 - 2.8e-37 127.2 0.1 6.6e-37 125.9 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EPE26251.1 - 3.8e-18 65.7 0.0 1.6e-17 63.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EPE26251.1 - 5.1e-15 55.1 0.0 1.4e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EPE26251.1 - 1.8e-10 40.5 0.0 6.8e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE26251.1 - 1.4e-09 37.8 0.0 8.7e-09 35.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EPE26251.1 - 1.5e-09 38.8 0.0 5.3e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EPE26251.1 - 1.8e-08 34.7 0.0 4.7e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE26251.1 - 1.1e-06 28.0 0.0 3.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.7 EPE26251.1 - 1.7e-06 27.7 0.1 4.5e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EPE26251.1 - 2.2e-06 28.2 0.0 8.2e-06 26.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EPE26251.1 - 2.2e-05 23.5 0.0 5.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 EPE26251.1 - 0.00025 21.3 0.0 0.001 19.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EPE26251.1 - 0.0097 16.1 0.1 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 EPE26251.1 - 0.019 14.9 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EPE26251.1 - 0.028 13.8 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DREV PF05219.7 EPE26251.1 - 0.079 11.8 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase CorA PF01544.13 EPE26252.1 - 2.6e-41 141.5 0.1 1.3e-40 139.2 0.1 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein NAD_binding_10 PF13460.1 EPE26253.1 - 1.1e-09 38.5 0.0 1.9e-09 37.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EPE26253.1 - 0.0027 17.6 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EPE26253.1 - 0.0034 16.8 0.0 0.0055 16.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EPE26253.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EPE26253.1 - 0.12 11.2 0.0 0.44 9.4 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.14 EPE26253.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_transf_25 PF01755.12 EPE26254.1 - 8.4e-05 22.2 0.2 0.00037 20.1 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) FAD_binding_3 PF01494.14 EPE26255.1 - 0.00012 21.2 0.0 0.00014 21.0 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EPE26256.1 - 9.2e-07 28.2 0.3 1.2e-05 24.6 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EPE26256.1 - 0.00011 22.1 0.0 0.00028 20.8 0.0 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE26256.1 - 0.00013 20.9 0.1 0.00064 18.7 0.1 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPE26256.1 - 0.0029 17.5 0.0 0.008 16.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE26256.1 - 0.0063 16.3 0.1 0.0086 15.8 0.0 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 EPE26256.1 - 0.02 14.0 0.0 0.43 9.6 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EPE26256.1 - 0.073 13.4 0.1 17 5.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EPE26256.1 - 0.085 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EPE26256.1 - 0.087 12.6 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F-box-like PF12937.2 EPE26257.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 F-box-like HET PF06985.6 EPE26258.1 - 1.1e-23 83.9 1.0 2.8e-23 82.5 0.7 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AIRC PF00731.15 EPE26260.1 - 4.4e-60 201.3 1.7 9e-60 200.3 1.2 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EPE26260.1 - 1.6e-51 174.0 0.0 2.5e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EPE26260.1 - 4.5e-13 49.3 0.0 8e-12 45.2 0.0 2.4 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EPE26260.1 - 2.2e-05 23.9 0.0 4.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.1 EPE26260.1 - 0.0017 18.6 0.0 0.041 14.2 0.0 2.5 2 0 0 2 2 2 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 EPE26260.1 - 0.0018 17.4 0.0 0.004 16.3 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Radical_SAM PF04055.16 EPE26260.1 - 0.0023 18.1 0.2 0.029 14.5 0.1 2.4 1 1 1 2 2 2 1 Radical SAM superfamily NAD_binding_2 PF03446.10 EPE26260.1 - 0.007 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ATP-grasp_3 PF02655.9 EPE26260.1 - 0.016 15.0 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPE26260.1 - 0.027 13.2 0.0 0.69 8.5 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon CbiG_C PF01890.11 EPE26260.1 - 0.039 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus TrkA_N PF02254.13 EPE26260.1 - 0.057 13.4 0.1 0.34 10.9 0.1 2.4 1 1 0 1 1 1 0 TrkA-N domain VIT1 PF01988.14 EPE26261.1 - 0.067 12.6 9.8 0.12 11.8 6.8 1.6 1 1 0 1 1 1 0 VIT family 7TMR-DISM_7TM PF07695.6 EPE26261.1 - 0.23 11.1 6.1 0.32 10.6 4.3 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF2232 PF09991.4 EPE26261.1 - 1.1 8.1 9.8 0.15 11.0 4.1 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Pkinase PF00069.20 EPE26262.1 - 7.2e-25 87.6 0.0 1.3e-24 86.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE26262.1 - 5.5e-11 42.0 0.0 0.00015 20.8 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 EPE26262.1 - 0.015 14.6 0.1 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EPE26262.1 - 0.07 12.8 0.2 0.26 10.9 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPE26262.1 - 0.18 10.5 0.3 0.27 9.9 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SH3_2 PF07653.12 EPE26264.1 - 0.072 12.5 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain Tachylectin PF14517.1 EPE26264.1 - 0.097 11.9 0.2 0.18 11.0 0.2 1.4 1 0 0 1 1 1 0 Tachylectin L_HGMIC_fpl PF10242.4 EPE26266.1 - 0.079 12.9 0.1 0.095 12.7 0.1 1.1 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein PAN_4 PF14295.1 EPE26267.1 - 0.00079 19.0 0.5 0.0018 17.9 0.3 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 EPE26267.1 - 0.0018 18.0 0.9 0.0018 18.0 0.6 1.8 2 0 0 2 2 2 1 PAN-like domain RRM_1 PF00076.17 EPE26268.1 - 2.5e-17 62.2 0.6 6e-17 61.0 0.2 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE26268.1 - 6.7e-12 45.2 0.1 1.1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE26268.1 - 2.5e-07 30.4 0.2 4.5e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DPCD PF14913.1 EPE26268.1 - 0.043 12.9 0.1 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 DPCD protein family Ank_2 PF12796.2 EPE26269.1 - 3.7e-18 65.6 0.2 2.1e-10 40.7 0.0 4.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPE26269.1 - 1.9e-12 46.3 10.4 1.6e-05 24.4 0.2 7.0 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.1 EPE26269.1 - 2.4e-09 37.1 9.5 0.00022 21.3 0.2 6.8 5 2 3 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE26269.1 - 1.9e-07 30.6 5.9 0.0021 18.1 0.0 5.2 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.1 EPE26269.1 - 9.4e-07 29.1 1.6 0.00012 22.4 0.0 4.5 4 2 1 5 5 5 2 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.1 EPE26269.1 - 0.0042 17.3 9.2 0.16 12.3 0.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE26269.1 - 0.022 15.0 11.5 0.13 12.6 0.8 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type CAP_N PF01213.14 EPE26270.1 - 0.061 12.6 0.9 0.082 12.1 0.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EPE26270.1 - 0.098 12.0 1.0 0.16 11.3 0.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3661 PF12400.3 EPE26272.1 - 1.5e-43 147.9 2.3 2.5e-43 147.2 1.6 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein DUF3292 PF11696.3 EPE26277.1 - 9.2 3.9 8.9 1.6 6.4 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3292) Peptidase_M22 PF00814.20 EPE26278.1 - 4.7e-48 164.0 0.3 5.3e-42 144.1 0.0 2.9 2 1 0 2 2 2 2 Glycoprotease family MFS_1 PF07690.11 EPE26279.1 - 2.1e-25 89.1 48.0 4.4e-25 88.1 30.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26279.1 - 2.4e-07 29.7 12.5 2.4e-07 29.7 8.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EPE26279.1 - 0.13 10.2 8.6 0.24 9.4 1.2 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2613 PF11021.3 EPE26279.1 - 1.2 8.8 0.0 1.2 8.8 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) DUF4448 PF14610.1 EPE26279.1 - 1.3 8.4 3.6 0.29 10.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Shisa PF13908.1 EPE26280.1 - 0.013 15.6 1.7 0.013 15.6 1.2 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Syndecan PF01034.15 EPE26280.1 - 0.021 14.4 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Rifin_STEVOR PF02009.11 EPE26280.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family DUF1191 PF06697.7 EPE26280.1 - 0.022 13.5 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Gemini_mov PF01708.11 EPE26280.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Geminivirus putative movement protein Methyltransf_2 PF00891.13 EPE26281.1 - 3.5e-26 91.8 0.0 4.6e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EPE26281.1 - 0.0095 16.5 0.0 0.033 14.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF2805 PF10985.3 EPE26281.1 - 0.054 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Methyltransf_16 PF10294.4 EPE26281.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Acetyltransf_1 PF00583.19 EPE26282.1 - 1.6e-12 47.2 0.1 2.2e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE26282.1 - 2.3e-09 37.2 0.0 3.2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE26282.1 - 1.8e-08 34.4 0.1 2.3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE26282.1 - 9.3e-06 25.5 0.0 2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPE26282.1 - 0.00067 19.6 0.0 0.00091 19.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EPE26282.1 - 0.013 15.1 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HET PF06985.6 EPE26283.1 - 3.6e-27 95.2 0.0 6.6e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clat_adaptor_s PF01217.15 EPE26284.1 - 3.9e-15 55.7 1.0 1.6e-06 27.9 0.0 2.9 2 1 0 2 2 2 2 Clathrin adaptor complex small chain Sua5_yciO_yrdC PF01300.13 EPE26285.1 - 1.5e-50 170.9 0.0 2.4e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EPE26285.1 - 3.4e-27 94.9 0.5 1.8e-26 92.6 0.4 2.0 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Proteasome PF00227.21 EPE26286.1 - 5.2e-48 162.8 0.3 6.5e-48 162.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3222 PF11519.3 EPE26286.1 - 0.11 12.4 0.6 11 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) DUF2233 PF09992.4 EPE26289.1 - 0.022 14.7 0.0 0.048 13.6 0.0 1.7 1 1 0 1 1 1 0 Predicted periplasmic protein (DUF2233) APH PF01636.18 EPE26291.1 - 3.7e-12 46.4 0.0 5e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE26291.1 - 1.3e-06 28.1 0.0 9.6e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EPE26291.1 - 0.071 12.2 0.1 6.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain BTB PF00651.26 EPE26292.1 - 2.8e-07 30.5 0.1 8.5e-07 28.9 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.13 EPE26293.1 - 2.4e-14 52.8 0.4 4.4e-14 51.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EPE26294.1 - 1.5e-21 77.0 0.5 4.1e-19 69.0 0.0 2.5 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 EPE26294.1 - 4.1e-08 33.0 0.0 7.9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE26294.1 - 0.00019 20.9 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE26294.1 - 0.0017 18.3 0.0 0.011 15.7 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPE26294.1 - 0.016 14.1 0.1 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPE26294.1 - 0.024 13.3 0.0 0.042 12.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPE26294.1 - 0.026 13.4 0.0 0.06 12.2 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein DUF2098 PF09871.4 EPE26296.1 - 0.079 12.8 0.1 0.32 10.9 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) AAA PF00004.24 EPE26297.1 - 6.5e-18 65.1 0.0 1.7e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE26297.1 - 5.8e-05 23.1 0.0 0.00021 21.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE26297.1 - 0.00045 20.3 0.1 0.0034 17.5 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EPE26297.1 - 0.014 15.2 0.0 0.046 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPE26297.1 - 0.024 14.3 0.0 0.073 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPE26297.1 - 0.038 13.7 0.7 0.096 12.4 0.5 1.7 1 0 0 1 1 1 0 Part of AAA domain CPT PF07931.7 EPE26297.1 - 0.047 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 EPE26297.1 - 0.87 10.4 9.2 0.19 12.5 0.3 3.9 2 1 1 3 3 3 0 AAA domain p450 PF00067.17 EPE26298.1 - 3.4e-36 124.7 0.1 8.3e-24 83.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Oxidored_FMN PF00724.15 EPE26299.1 - 6.2e-72 242.4 0.0 1.6e-69 234.4 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SUR7 PF06687.7 EPE26300.1 - 0.0018 17.8 8.0 0.0038 16.8 5.5 1.5 1 1 0 1 1 1 1 SUR7/PalI family MARVEL PF01284.18 EPE26300.1 - 0.023 14.5 8.0 0.24 11.1 5.0 2.1 1 1 0 1 1 1 0 Membrane-associating domain DUF747 PF05346.6 EPE26300.1 - 0.033 13.2 0.1 0.059 12.4 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic membrane protein family Claudin_3 PF06653.6 EPE26300.1 - 0.34 10.6 7.0 1.4 8.6 0.4 2.5 2 1 1 3 3 3 0 Tight junction protein, Claudin-like DUF3953 PF13129.1 EPE26300.1 - 0.47 10.1 10.9 0.82 9.3 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) DUF1218 PF06749.7 EPE26300.1 - 0.65 10.4 4.4 1.1 9.8 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) YjgP_YjgQ PF03739.9 EPE26300.1 - 0.83 8.3 6.4 0.061 12.0 0.1 1.9 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4282 PF14110.1 EPE26300.1 - 0.96 9.6 4.9 1.8 8.7 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) CbiQ PF02361.11 EPE26300.1 - 1.3 8.5 6.6 9.2 5.7 4.5 2.0 1 1 0 1 1 1 0 Cobalt transport protein ATP-synt_8 PF00895.15 EPE26300.1 - 3.5 7.9 7.4 12 6.2 0.1 2.9 3 0 0 3 3 3 0 ATP synthase protein 8 Peptidase_C15 PF01470.12 EPE26302.1 - 1.2e-07 31.8 0.0 3e-07 30.4 0.0 1.5 1 1 1 2 2 2 1 Pyroglutamyl peptidase O-FucT PF10250.4 EPE26303.1 - 3.8e-08 32.8 0.3 6.5e-06 25.4 0.2 2.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CoA_trans PF01144.18 EPE26304.1 - 4.4e-95 316.9 1.8 2.3e-54 183.8 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Thiolase_N PF00108.18 EPE26305.1 - 3e-73 246.0 0.3 4.1e-73 245.5 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lyase_1 PF00206.15 EPE26305.1 - 5.2e-46 157.2 0.0 9.6e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Lyase Thiolase_C PF02803.13 EPE26305.1 - 4e-36 123.1 0.0 1e-35 121.8 0.0 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ADSL_C PF10397.4 EPE26305.1 - 4.3e-16 58.6 0.0 1e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ketoacyl-synt PF00109.21 EPE26305.1 - 0.00088 18.8 0.1 0.0016 18.0 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EPE26305.1 - 0.012 15.2 0.1 0.15 11.7 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HgmA PF04209.8 EPE26306.1 - 9.2e-129 429.5 0.0 1.1e-128 429.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Fungal_trans PF04082.13 EPE26307.1 - 2.7e-15 55.9 1.0 4.6e-15 55.1 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPE26307.1 - 1.1e-07 31.7 17.8 0.0015 18.7 3.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE26307.1 - 4.4e-06 26.6 15.2 0.01 16.1 2.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE26307.1 - 1.4e-05 25.1 12.4 3.9e-05 23.7 4.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EPE26307.1 - 0.0083 15.9 1.0 0.0083 15.9 0.7 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger Plasmid_RAQPRD PF09686.5 EPE26307.1 - 0.012 15.7 0.1 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) zf-C2H2_jaz PF12171.3 EPE26307.1 - 0.9 9.7 10.1 0.09 12.9 2.4 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding p450 PF00067.17 EPE26308.1 - 5.3e-65 219.7 0.0 1.3e-64 218.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EPE26309.1 - 1.7e-32 112.5 24.4 1.7e-32 112.5 16.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_tranf_2_4 PF13704.1 EPE26310.1 - 5.9e-12 45.7 0.6 1.4e-11 44.5 0.4 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 EPE26310.1 - 4.1e-08 32.8 0.3 7.1e-08 32.0 0.2 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 92 Nuc_sug_transp PF04142.10 EPE26311.1 - 7.8e-23 80.8 0.7 1.3e-22 80.0 0.5 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EPE26311.1 - 0.014 15.0 1.8 0.014 15.0 1.2 2.9 2 1 0 2 2 2 0 Triose-phosphate Transporter family FAD_binding_3 PF01494.14 EPE26312.1 - 6e-51 173.5 0.0 7.5e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE26312.1 - 1.3e-05 24.3 0.7 0.0025 16.7 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPE26312.1 - 5.2e-05 23.5 0.1 0.04 14.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE26312.1 - 5.3e-05 23.1 0.4 0.00024 21.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EPE26312.1 - 0.00043 19.0 1.6 0.31 9.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 EPE26312.1 - 0.0012 17.4 0.1 0.003 16.0 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EPE26312.1 - 0.0065 15.5 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EPE26312.1 - 0.0096 15.8 0.0 0.031 14.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE26312.1 - 0.013 14.3 0.1 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPE26312.1 - 0.014 14.2 0.9 0.34 9.7 0.1 2.1 1 1 1 2 2 2 0 FAD binding domain Mqo PF06039.10 EPE26312.1 - 0.024 12.8 0.0 0.038 12.1 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 EPE26312.1 - 0.09 12.5 0.4 1.5 8.5 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding IBR PF01485.16 EPE26313.1 - 4.1e-11 42.5 45.0 4.8e-06 26.3 9.1 3.6 3 1 0 3 3 3 3 IBR domain zf-RING_2 PF13639.1 EPE26313.1 - 0.0092 15.7 4.8 0.0092 15.7 3.4 3.8 2 1 1 3 3 3 1 Ring finger domain AAA PF00004.24 EPE26314.1 - 3.3e-18 66.1 0.0 5.7e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE26314.1 - 0.002 18.2 0.2 0.027 14.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EPE26314.1 - 0.0025 18.0 0.0 0.15 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPE26314.1 - 0.0026 17.7 0.0 0.0071 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EPE26314.1 - 0.0031 17.2 0.0 0.0071 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EPE26314.1 - 0.04 12.9 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 EPE26314.1 - 0.05 12.7 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC Zot PF05707.7 EPE26314.1 - 0.06 12.8 0.1 1.1 8.7 0.0 2.3 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) NACHT PF05729.7 EPE26314.1 - 0.07 12.7 0.0 3.5 7.2 0.0 2.7 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.17 EPE26314.1 - 0.089 12.9 0.0 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Cyclase PF04199.8 EPE26315.1 - 9.9e-16 57.8 0.0 1.5e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 EPE26315.1 - 0.031 13.6 0.0 0.95 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Sigma70_r4 PF04545.11 EPE26315.1 - 0.18 11.1 0.0 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 Hydant_A_N PF05378.8 EPE26315.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.4 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Fructosamin_kin PF03881.9 EPE26316.1 - 1.4e-32 112.8 0.0 1.9e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase WD40 PF00400.27 EPE26317.1 - 5.5e-07 29.2 13.7 0.68 9.9 0.0 7.6 8 1 0 8 8 8 3 WD domain, G-beta repeat Abhydrolase_5 PF12695.2 EPE26317.1 - 2.5e-05 24.0 0.0 6.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPE26317.1 - 0.00018 21.1 0.1 0.00048 19.7 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EPE26317.1 - 0.0004 19.7 0.0 0.00083 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPE26317.1 - 0.00053 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EPE26317.1 - 0.0048 16.2 0.0 0.0097 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) NACHT PF05729.7 EPE26317.1 - 0.048 13.3 0.0 0.29 10.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EPE26317.1 - 0.049 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF3328 PF11807.3 EPE26318.1 - 9.9e-47 159.4 1.0 1.2e-46 159.1 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) CENP-O PF09496.5 EPE26319.1 - 1.3e-09 38.1 1.7 2 8.7 0.2 7.9 1 1 4 5 5 5 2 Cenp-O kinetochore centromere component YqcI_YcgG PF08892.6 EPE26319.1 - 0.021 14.4 16.8 10 5.6 0.2 6.9 1 1 10 11 11 11 0 YqcI/YcgG family Pantoate_ligase PF02569.10 EPE26319.1 - 0.022 13.5 15.6 3.6 6.2 0.0 7.7 2 1 6 10 10 10 0 Pantoate-beta-alanine ligase DUF3889 PF13028.1 EPE26319.1 - 0.023 14.3 18.7 1.6 8.4 0.4 5.5 1 1 6 7 7 7 0 Protein of unknown function (DUF3889) Hormone_3 PF00159.13 EPE26319.1 - 0.078 12.9 25.1 57 3.8 0.0 12.2 8 3 5 14 14 14 0 Pancreatic hormone peptide Staph_haemo PF05480.6 EPE26319.1 - 0.081 12.6 8.6 1.5e+02 2.2 0.0 8.1 9 1 1 11 11 11 0 Staphylococcus haemolytic protein Phage_min_cap2 PF06152.6 EPE26319.1 - 0.1 11.5 3.2 7 5.5 0.0 3.5 1 1 2 3 3 3 0 Phage minor capsid protein 2 DUF1170 PF06663.8 EPE26319.1 - 0.12 12.3 5.2 8.5 6.2 0.1 4.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1170) RE_XcyI PF09571.5 EPE26319.1 - 0.13 11.1 20.1 5.1 5.8 0.1 7.7 1 1 9 10 10 10 0 XcyI restriction endonuclease Egg_lysin PF01303.12 EPE26319.1 - 0.22 11.4 1.3 6.6 6.7 0.1 3.4 1 1 3 4 4 4 0 Egg lysin (Sperm-lysin) HPPK PF01288.15 EPE26319.1 - 0.3 10.8 8.1 22 4.8 0.6 4.8 1 1 3 4 4 4 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Acetyltransf_1 PF00583.19 EPE26320.1 - 1.6e-12 47.2 0.0 2.7e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EPE26320.1 - 2.4e-12 47.2 0.0 3.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPE26320.1 - 1.2e-07 31.7 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPE26320.1 - 0.0032 17.5 0.1 0.0083 16.2 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPE26320.1 - 0.032 14.1 0.0 0.043 13.7 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain COesterase PF00135.23 EPE26321.1 - 3.8e-64 217.3 0.0 5.1e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE26321.1 - 5.6e-06 26.0 0.0 1.5e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DHQ_synthase PF01761.15 EPE26321.1 - 0.18 10.6 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 3-dehydroquinate synthase PTR2 PF00854.16 EPE26322.1 - 1.3e-20 73.5 6.6 2.7e-20 72.4 0.4 2.5 2 1 0 2 2 2 1 POT family MFS_1 PF07690.11 EPE26322.1 - 4.7e-07 28.8 4.2 4.7e-07 28.8 2.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Caps_synth_CapC PF14102.1 EPE26322.1 - 0.012 15.7 0.3 0.99 9.5 0.1 2.5 2 0 0 2 2 2 0 Capsule biosynthesis CapC MCM PF00493.18 EPE26323.1 - 1.6e-140 467.6 0.0 2.2e-140 467.1 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPE26323.1 - 1.3e-24 87.0 0.0 1.3e-23 83.7 0.0 2.7 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPE26323.1 - 9.1e-06 24.9 0.0 0.00034 19.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPE26323.1 - 3.2e-05 23.6 0.0 0.00026 20.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPE26323.1 - 0.0012 18.4 0.0 0.0042 16.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 EPE26323.1 - 0.008 14.8 5.2 0.015 14.0 0.4 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase_2 PF13335.1 EPE26323.1 - 0.035 14.5 5.2 0.15 12.4 1.5 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI TraT PF05818.7 EPE26323.1 - 0.041 13.3 0.6 0.72 9.2 0.0 2.5 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein FAD-oxidase_C PF02913.14 EPE26325.1 - 5.7e-55 186.3 0.1 9e-55 185.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EPE26325.1 - 1.3e-35 121.9 0.0 2e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 EPE26325.1 - 1.1e-05 24.0 0.2 3.2e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) AT_hook PF02178.14 EPE26325.1 - 0.092 12.4 1.3 0.23 11.2 0.9 1.7 1 0 0 1 1 1 0 AT hook motif Phytase-like PF13449.1 EPE26327.1 - 1e-25 90.7 0.0 2.1e-25 89.6 0.0 1.7 1 1 0 1 1 1 1 Esterase-like activity of phytase Cellulase PF00150.13 EPE26328.1 - 5.2e-47 160.3 0.0 6.6e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fer4_9 PF13187.1 EPE26329.1 - 0.098 12.9 0.6 0.17 12.2 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain CorA PF01544.13 EPE26332.1 - 0.11 11.5 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TIG PF01833.19 EPE26335.1 - 6.4e-05 22.8 0.9 0.00017 21.4 0.1 2.3 2 0 0 2 2 2 1 IPT/TIG domain CARDB PF07705.6 EPE26335.1 - 0.00021 21.2 0.2 0.00077 19.4 0.2 1.9 1 0 0 1 1 1 1 CARDB Reprolysin_5 PF13688.1 EPE26335.1 - 0.00031 20.7 0.0 0.00078 19.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EPE26335.1 - 0.00047 20.2 0.1 0.0009 19.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EPE26335.1 - 0.0072 16.8 0.3 0.015 15.7 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EPE26335.1 - 0.11 12.0 0.1 0.24 10.9 0.0 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3254 PF11630.3 EPE26335.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) Rad50_zn_hook PF04423.9 EPE26337.1 - 0.61 9.5 4.1 0.32 10.4 1.1 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif COG4 PF08318.7 EPE26339.1 - 1.6e-96 322.9 0.0 2.1e-96 322.5 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein E1-E2_ATPase PF00122.15 EPE26340.1 - 8.8e-73 244.1 0.5 1.5e-72 243.3 0.3 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPE26340.1 - 6.4e-46 156.1 0.7 1.3e-45 155.1 0.5 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPE26340.1 - 5.4e-30 105.4 0.0 1.3e-28 100.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPE26340.1 - 5.6e-21 73.7 0.1 1.5e-20 72.3 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EPE26340.1 - 7.7e-14 51.4 0.0 1.4e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPE26340.1 - 8.5e-13 48.8 0.0 2.9e-12 47.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPE26340.1 - 0.00016 21.3 1.1 0.00016 21.3 0.7 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 EPE26341.1 - 9.6e-39 131.7 0.0 1.6e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EPE26341.1 - 8.3e-09 34.5 0.5 2.2e-08 33.1 0.3 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EPE26341.1 - 0.0025 17.4 0.0 0.02 14.4 0.0 2.2 2 0 0 2 2 2 1 ScpA/B protein DUF3533 PF12051.3 EPE26342.1 - 9e-92 307.7 21.9 1.1e-91 307.4 15.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) adh_short PF00106.20 EPE26343.1 - 5e-25 88.3 1.3 7.1e-25 87.8 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE26343.1 - 1.2e-24 87.3 0.0 1.6e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE26343.1 - 4.6e-12 45.9 0.4 6.7e-12 45.4 0.3 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EPE26343.1 - 0.021 13.8 0.3 0.055 12.5 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1372 PF07116.6 EPE26343.1 - 0.03 14.2 0.1 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) Fungal_trans_2 PF11951.3 EPE26345.1 - 1.2e-11 43.8 0.0 1.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AGTRAP PF06396.6 EPE26346.1 - 0.011 15.4 0.4 0.011 15.4 0.2 2.6 1 1 1 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) gag-asp_proteas PF13975.1 EPE26348.1 - 0.019 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease AhpC-TSA PF00578.16 EPE26348.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family DUF870 PF05912.6 EPE26350.1 - 0.0015 18.3 0.6 0.0024 17.6 0.4 1.3 1 0 0 1 1 1 1 Caenorhabditis elegans protein of unknown function (DUF870) DUF3431 PF11913.3 EPE26350.1 - 0.058 12.8 0.2 0.067 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) BON PF04972.12 EPE26350.1 - 0.095 12.4 0.1 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 BON domain DUF1752 PF08550.5 EPE26352.1 - 1.4e-07 30.9 7.3 2.9e-07 29.9 5.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) NgoMIV_restric PF09015.5 EPE26352.1 - 0.042 12.8 0.8 0.097 11.6 0.1 1.8 2 0 0 2 2 2 0 NgoMIV restriction enzyme adh_short PF00106.20 EPE26353.1 - 2.7e-17 63.1 0.0 5.5e-17 62.1 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE26353.1 - 1.8e-08 34.4 0.0 3.9e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPE26353.1 - 0.00018 21.0 0.0 0.00037 20.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EPE26353.1 - 0.028 13.9 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase KR PF08659.5 EPE26353.1 - 0.077 12.6 0.1 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 KR domain p450 PF00067.17 EPE26354.1 - 1.1e-55 189.0 0.0 1.3e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MEDS PF14417.1 EPE26354.1 - 0.058 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain MFS_1 PF07690.11 EPE26355.1 - 1e-27 96.7 68.9 5.3e-24 84.5 30.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EPE26355.1 - 1.8e-06 27.6 8.3 0.0012 18.6 1.9 3.7 4 0 0 4 4 4 2 MFS_1 like family TraT PF05818.7 EPE26355.1 - 8 5.8 6.5 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Fungal_trans PF04082.13 EPE26356.1 - 1.3e-16 60.3 1.3 2.4e-16 59.3 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE26356.1 - 3e-08 33.4 9.3 6.1e-08 32.4 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EPE26356.1 - 4.1 7.6 9.8 8.3 6.6 6.8 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Tetraspannin PF00335.15 EPE26357.1 - 0.87 8.8 5.2 0.42 9.8 1.4 2.3 2 1 0 2 2 2 0 Tetraspanin family DUF1479 PF07350.7 EPE26358.1 - 7.9e-165 548.3 0.0 9.1e-165 548.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EPE26358.1 - 0.0099 15.9 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DUF3425 PF11905.3 EPE26359.1 - 7.9e-16 58.1 0.0 1.9e-15 56.9 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) TMEM51 PF15345.1 EPE26359.1 - 0.12 12.0 1.6 0.16 11.6 1.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 MCM2_N PF12619.3 EPE26359.1 - 0.14 12.1 4.0 0.2 11.6 2.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 ubiquitin PF00240.18 EPE26360.1 - 0.006 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF1399 PF07173.7 EPE26360.1 - 0.046 14.0 0.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1399) TUG-UBL1 PF11470.3 EPE26361.1 - 0.007 16.2 0.3 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 GLUT4 regulating protein TUG XAP5 PF04921.9 EPE26361.1 - 0.026 14.0 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator LUC7 PF03194.10 EPE26363.1 - 9.3e-71 238.3 0.6 1.1e-70 238.0 0.4 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF4200 PF13863.1 EPE26363.1 - 0.019 14.8 0.9 0.067 13.1 0.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) zf-C4H2 PF10146.4 EPE26363.1 - 0.031 14.3 0.9 0.044 13.7 0.6 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Occludin_ELL PF07303.8 EPE26363.1 - 0.57 10.9 3.1 1.2 9.9 0.3 2.3 1 1 1 2 2 2 0 Occludin homology domain Gpi16 PF04113.9 EPE26364.1 - 6.2e-237 787.1 0.0 8.1e-237 786.7 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Glyco_hydro_18 PF00704.23 EPE26365.1 - 1.4e-95 320.7 12.3 1.6e-95 320.4 8.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 p450 PF00067.17 EPE26366.1 - 9.8e-75 251.8 0.0 1.6e-74 251.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EPE26366.1 - 6.8e-37 127.0 0.0 1.2e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EPE26366.1 - 2.5e-22 79.4 0.4 7.2e-22 77.9 0.0 2.1 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EPE26366.1 - 1.6e-14 54.3 0.2 5.4e-14 52.6 0.1 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EPE26366.1 - 0.001 19.0 0.0 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.6 EPE26366.1 - 0.0033 17.3 0.0 0.0082 16.0 0.0 1.7 1 0 0 1 1 1 1 NrdI Flavodoxin like XOO_2897-deam PF14440.1 EPE26366.1 - 0.074 12.7 0.1 0.19 11.4 0.1 1.7 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Sugar_tr PF00083.19 EPE26367.1 - 5.7e-83 278.9 21.3 6.7e-83 278.7 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE26367.1 - 7.3e-37 126.8 17.5 7.3e-37 126.8 12.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPE26367.1 - 0.00033 18.9 2.6 0.00033 18.9 1.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cons_hypoth698 PF03601.9 EPE26367.1 - 0.048 12.2 7.0 0.08 11.5 0.8 2.4 2 0 0 2 2 2 0 Conserved hypothetical protein 698 Ribophorin_I PF04597.9 EPE26369.1 - 1.4e-149 498.2 0.2 1.6e-149 498.0 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I Prok-E2_E PF14462.1 EPE26369.1 - 0.062 12.8 0.1 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family E Hexokinase_2 PF03727.11 EPE26370.1 - 4.8e-87 291.2 0.0 7.1e-87 290.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EPE26370.1 - 2.7e-76 255.5 0.0 7.8e-75 250.7 0.0 2.1 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.16 EPE26370.1 - 0.07 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain MiAMP1 PF09117.5 EPE26370.1 - 0.098 13.0 0.3 0.27 11.6 0.1 1.7 2 0 0 2 2 2 0 MiAMP1 Ank_2 PF12796.2 EPE26371.1 - 6.1e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE26371.1 - 0.16 12.5 0.0 41 4.8 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) VTC PF09359.5 EPE26372.1 - 6.8e-99 330.4 1.1 7.9e-99 330.2 0.0 1.6 2 0 0 2 2 2 1 VTC domain DUF3328 PF11807.3 EPE26372.1 - 6.8e-28 97.8 0.1 2.1e-27 96.2 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) SPX PF03105.14 EPE26372.1 - 7.8e-24 84.9 14.3 3e-22 79.6 7.5 3.1 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EPE26372.1 - 3.8e-12 46.2 4.5 2.6e-11 43.5 2.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) FixQ PF05545.6 EPE26372.1 - 0.0062 16.1 2.5 0.05 13.2 0.7 2.4 2 0 0 2 2 2 1 Cbb3-type cytochrome oxidase component FixQ LXG PF04740.7 EPE26372.1 - 0.084 12.6 2.4 0.78 9.4 0.1 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily PMP22_Claudin PF00822.15 EPE26372.1 - 0.19 11.3 1.2 0.53 9.9 0.4 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family NmrA PF05368.8 EPE26373.1 - 6.5e-15 55.0 0.0 8.2e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE26373.1 - 2e-12 47.5 0.0 9.1e-12 45.3 0.0 1.8 1 1 1 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EPE26373.1 - 2.6e-05 24.5 0.0 5.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EPE26373.1 - 0.022 14.6 0.0 0.093 12.6 0.0 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EPE26373.1 - 0.025 14.0 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family zf-C3HC4_3 PF13920.1 EPE26375.1 - 0.0017 17.9 1.2 0.0039 16.8 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Hemerythrin PF01814.18 EPE26376.1 - 1.4e-10 41.3 0.3 1.9e-10 40.9 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain AXE1 PF05448.7 EPE26377.1 - 0.0081 14.7 0.1 0.026 13.0 0.1 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) PhoPQ_related PF10142.4 EPE26377.1 - 0.065 11.7 0.0 0.1 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Ppx-GppA PF02541.11 EPE26378.1 - 2.7e-41 141.6 0.0 3.9e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Glycolytic PF00274.14 EPE26378.1 - 0.046 12.1 0.1 10 4.3 0.0 3.2 3 1 0 4 4 4 0 Fructose-bisphosphate aldolase class-I FAD_binding_4 PF01565.18 EPE26379.1 - 1.4e-16 60.2 0.0 2.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.20 EPE26380.1 - 7.4e-14 52.0 0.3 1.1e-13 51.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE26380.1 - 1.2e-05 25.0 0.1 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE26380.1 - 2.7e-05 24.0 0.1 4.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EPE26380.1 - 0.013 15.2 1.0 0.044 13.5 0.3 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EPE26380.1 - 0.035 14.1 1.2 0.12 12.4 0.8 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EPE26380.1 - 0.068 12.0 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 EPE26382.1 - 6.5e-06 25.2 0.1 6.5e-06 25.2 0.1 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain BBE PF08031.7 EPE26383.1 - 1.3e-07 31.3 3.1 1.3e-07 31.3 2.1 2.6 3 0 0 3 3 3 1 Berberine and berberine like Cytokin-bind PF09265.5 EPE26383.1 - 0.072 12.2 0.9 0.19 10.8 0.2 1.6 1 1 1 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Tyrosinase PF00264.15 EPE26384.1 - 4.7e-43 147.9 5.5 6.8e-43 147.3 3.8 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase NACHT PF05729.7 EPE26384.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AsnA PF03590.10 EPE26384.1 - 0.058 12.8 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Aspartate-ammonia ligase MFS_1 PF07690.11 EPE26385.1 - 1.7e-30 105.9 38.5 3.2e-28 98.4 26.7 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26385.1 - 1.5e-14 53.4 12.3 1.5e-14 53.4 8.5 2.4 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EPE26385.1 - 3e-05 22.4 4.4 5.7e-05 21.5 3.1 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Asp-Al_Ex PF06826.7 EPE26385.1 - 5.1e-05 22.8 7.0 0.00016 21.2 4.8 1.8 1 0 0 1 1 1 1 Predicted Permease Membrane Region DUF4360 PF14273.1 EPE26386.1 - 3.7e-20 72.3 0.2 4.7e-20 72.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Chitin_synth_1 PF01644.12 EPE26386.1 - 0.051 13.3 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Chitin synthase SET PF00856.23 EPE26387.1 - 9.4e-05 22.7 0.1 0.00023 21.5 0.0 1.6 1 0 0 1 1 1 1 SET domain Chitin_bind_3 PF03067.10 EPE26388.1 - 0.009 16.2 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain GAT PF03127.9 EPE26389.1 - 1.1e-16 60.6 1.3 5.2e-16 58.4 0.3 2.1 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 EPE26389.1 - 4.8e-05 23.0 0.0 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 VHS domain Peptidase_M28 PF04389.12 EPE26391.1 - 5.1e-31 107.7 0.0 7.6e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EPE26391.1 - 1.7e-13 50.0 0.1 3.9e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EPE26391.1 - 9.3e-06 25.2 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EPE26391.1 - 0.023 13.4 0.2 0.44 9.2 0.0 2.3 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase HEAT_EZ PF13513.1 EPE26392.1 - 3.1e-12 46.5 7.5 5.9e-05 23.4 0.0 8.8 7 2 2 9 9 9 3 HEAT-like repeat HEAT PF02985.17 EPE26392.1 - 3.8e-11 42.1 7.4 0.17 12.0 0.0 8.5 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 EPE26392.1 - 1e-10 41.7 13.9 0.0011 19.1 0.0 7.0 3 2 6 9 9 9 4 HEAT repeats IBN_N PF03810.14 EPE26392.1 - 1.3e-09 37.8 6.0 1e-08 34.9 0.7 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EPE26392.1 - 2.5e-06 27.0 0.1 1.1 8.5 0.0 5.1 2 1 2 4 4 4 1 CLASP N terminal Xpo1 PF08389.7 EPE26392.1 - 4.1e-05 23.5 2.5 1.3 8.9 0.0 5.8 4 1 1 5 5 5 1 Exportin 1-like protein RIX1 PF08167.7 EPE26392.1 - 0.00081 19.1 0.3 0.33 10.6 0.0 3.8 1 1 3 4 4 4 2 rRNA processing/ribosome biogenesis Arm PF00514.18 EPE26392.1 - 0.009 15.8 0.1 34 4.4 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cse1 PF08506.5 EPE26392.1 - 0.022 13.3 0.0 1.4 7.4 0.0 3.4 3 1 1 4 4 4 0 Cse1 Cnd1 PF12717.2 EPE26392.1 - 0.096 12.5 0.5 3.6 7.4 0.0 3.7 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 EPE26392.1 - 0.39 11.3 3.9 1.6e+02 3.2 0.1 5.2 6 0 0 6 6 3 0 PBS lyase HEAT-like repeat HMGL-like PF00682.14 EPE26393.1 - 5.2e-66 222.6 0.0 9.3e-66 221.8 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EPE26393.1 - 6.5e-24 84.2 0.0 1.4e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain UCH PF00443.24 EPE26394.1 - 7.7e-49 166.2 0.0 9.4e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPE26394.1 - 2.9e-19 69.6 0.0 1.1e-18 67.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EPE26394.1 - 2.5e-09 36.4 0.1 5.6e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Thaumatin PF00314.12 EPE26395.1 - 1.3e-64 217.5 1.3 1.6e-64 217.2 0.9 1.1 1 0 0 1 1 1 1 Thaumatin family DUF2235 PF09994.4 EPE26397.1 - 4.5e-22 78.7 0.1 8.4e-11 41.7 0.0 2.0 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Hexokinase_1 PF00349.16 EPE26398.1 - 1.7e-63 213.7 0.1 2.7e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EPE26398.1 - 1.6e-61 207.5 2.8 1.4e-46 158.7 0.0 2.3 2 0 0 2 2 2 2 Hexokinase HSP70 PF00012.15 EPE26400.1 - 6.6e-12 44.1 0.3 2.4e-10 38.9 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EPE26400.1 - 0.0028 17.2 0.1 0.006 16.2 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EPE26400.1 - 0.02 13.4 0.1 0.11 11.1 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Mem_trans PF03547.13 EPE26403.1 - 2.6e-50 170.8 1.3 4.7e-50 169.9 0.9 1.4 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 EPE26404.1 - 2.9e-48 164.2 0.0 2.1e-45 154.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE26404.1 - 3.2e-30 105.0 0.0 6.6e-29 100.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE26404.1 - 0.0018 17.2 0.0 0.0028 16.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EPE26404.1 - 0.041 12.7 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 EPE26405.1 - 9.6e-62 208.2 0.0 1.8e-61 207.3 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EPE26405.1 - 2.7e-20 71.5 0.0 5.1e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EPE26405.1 - 8e-06 25.7 0.4 0.00012 21.8 0.0 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Rad21_Rec8_N PF04825.8 EPE26406.1 - 1.1e-33 115.5 0.6 2.2e-33 114.4 0.4 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EPE26406.1 - 0.00021 20.3 0.0 0.00044 19.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein TRP PF06011.7 EPE26407.1 - 3.5e-102 342.2 27.1 5.6e-57 193.2 7.6 2.4 3 0 0 3 3 3 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPE26407.1 - 2.2e-27 95.8 0.1 3.6e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 ML-like domain Ank_2 PF12796.2 EPE26409.1 - 9.3e-10 38.7 0.0 5.7e-09 36.1 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE26409.1 - 5.9e-08 32.1 0.2 0.017 14.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EPE26409.1 - 2.5e-07 31.0 0.1 0.00067 20.1 0.0 3.7 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE26409.1 - 7.8e-07 28.7 1.3 0.18 12.1 0.0 4.4 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EPE26409.1 - 0.00011 22.3 0.7 2.1 8.7 0.0 4.5 3 1 2 5 5 5 1 Ankyrin repeats (many copies) TFIIS_C PF01096.13 EPE26410.1 - 3.9e-11 42.4 0.2 3.9e-11 42.4 0.2 2.9 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EPE26410.1 - 1.9e-05 24.2 4.5 1.9e-05 24.2 3.1 2.6 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit Med31 PF05669.7 EPE26411.1 - 4.4e-37 125.9 0.1 5.1e-37 125.7 0.1 1.0 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.6 EPE26414.1 - 2.7e-49 167.2 0.5 2.7e-49 167.2 0.3 2.0 2 0 0 2 2 2 1 Pal1 cell morphology protein UBA_4 PF14555.1 EPE26416.1 - 2.5e-10 39.6 0.0 5.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EPE26416.1 - 1.2e-06 28.4 0.0 2.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 UBX domain DUF742 PF05331.6 EPE26416.1 - 0.0018 17.8 0.0 0.0076 15.8 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF742) Cation_ATPase_N PF00690.21 EPE26416.1 - 0.085 12.3 0.1 0.34 10.4 0.0 2.0 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Pkinase PF00069.20 EPE26418.1 - 0.0049 16.0 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LSM PF01423.17 EPE26419.1 - 7.3e-14 51.0 0.0 9.7e-14 50.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 EPE26419.1 - 0.0013 19.1 6.9 0.002 18.5 4.8 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Gly-rich_Ago1 PF12764.2 EPE26419.1 - 2.5 8.7 10.0 4.1 8.0 7.0 1.4 1 0 0 1 1 1 0 Glycine-rich region of argonaut Zn_clus PF00172.13 EPE26420.1 - 0.0033 17.3 9.6 0.1 12.5 0.3 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_UL73 PF03554.8 EPE26421.1 - 0.15 11.8 3.0 0.14 11.9 0.9 1.8 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein BTB PF00651.26 EPE26422.1 - 7.8e-24 83.8 0.9 5.1e-13 48.9 0.6 3.5 4 0 0 4 4 4 2 BTB/POZ domain Ank_5 PF13857.1 EPE26422.1 - 3.9e-10 39.6 1.0 6.6e-07 29.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPE26422.1 - 4.7e-09 36.4 0.0 1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE26422.1 - 5.7e-09 35.3 0.6 1.8e-06 27.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EPE26422.1 - 4.1e-08 33.5 0.1 1e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE26422.1 - 0.0011 19.0 0.2 0.015 15.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat YqzH PF14164.1 EPE26422.1 - 0.19 11.6 2.0 18 5.3 1.0 2.8 2 0 0 2 2 2 0 YqzH-like protein Palm_thioest PF02089.10 EPE26423.1 - 2.5e-54 184.0 0.0 3.4e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 EPE26423.1 - 0.022 13.8 0.0 0.081 12.0 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 EPE26423.1 - 0.044 13.6 0.0 0.097 12.5 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Lipase_2 PF01674.13 EPE26423.1 - 0.061 12.6 0.0 0.29 10.3 0.0 2.2 1 1 0 1 1 1 0 Lipase (class 2) Ribosomal_L1 PF00687.16 EPE26424.1 - 7.8e-58 195.4 2.1 7.8e-58 195.4 1.4 2.0 2 1 1 3 3 3 1 Ribosomal protein L1p/L10e family Nbl1_Borealin_N PF10444.4 EPE26424.1 - 0.074 12.4 0.5 0.2 11.0 0.4 1.7 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Lipase_GDSL_2 PF13472.1 EPE26425.1 - 5.3e-08 33.2 0.0 4.6e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE26425.1 - 3.5e-06 27.0 0.0 1e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EPE26425.1 - 0.025 14.3 0.0 0.057 13.1 0.0 1.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family GDI PF00996.13 EPE26426.1 - 8.1e-37 126.5 0.0 1.1e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Asp PF00026.18 EPE26427.1 - 0.00038 19.7 0.0 0.001 18.3 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.5 EPE26427.1 - 0.0022 17.2 0.3 0.0054 16.0 0.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2561 PF10812.3 EPE26427.1 - 0.0034 17.0 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Protocadherin PF08374.6 EPE26430.1 - 0.084 12.5 0.7 0.1 12.2 0.5 1.1 1 0 0 1 1 1 0 Protocadherin FUSC-like PF12805.2 EPE26431.1 - 0.062 12.2 2.2 0.074 11.9 1.5 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS PHD PF00628.24 EPE26432.1 - 2e-09 37.0 11.6 5e-09 35.7 8.1 1.7 1 0 0 1 1 1 1 PHD-finger DUF2365 PF10157.4 EPE26433.1 - 0.0043 16.9 0.1 0.0059 16.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) DASH_Dad2 PF08654.5 EPE26433.1 - 0.017 15.1 0.2 0.73 9.8 0.0 2.3 1 1 1 2 2 2 0 DASH complex subunit Dad2 HSBP1 PF06825.7 EPE26433.1 - 0.023 14.2 1.9 1.2 8.7 0.1 2.7 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Not3 PF04065.10 EPE26433.1 - 0.028 13.6 2.4 0.035 13.3 0.9 1.6 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component PLU-1 PF08429.6 EPE26433.1 - 0.031 13.1 0.6 0.039 12.8 0.4 1.1 1 0 0 1 1 1 0 PLU-1-like protein BBP1_C PF15272.1 EPE26433.1 - 0.088 12.3 2.4 0.14 11.6 1.7 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal YscO PF07321.7 EPE26433.1 - 0.12 12.2 7.6 0.22 11.3 3.2 2.5 2 1 0 2 2 2 0 Type III secretion protein YscO IncA PF04156.9 EPE26433.1 - 0.24 10.9 5.9 0.3 10.6 4.0 1.3 1 1 0 1 1 1 0 IncA protein Syntaxin PF00804.20 EPE26433.1 - 1.2 9.3 4.8 1.8e+02 2.3 0.1 2.5 1 1 0 1 1 1 0 Syntaxin UreE_C PF05194.7 EPE26433.1 - 2.2 8.4 12.3 1.9 8.6 6.7 2.2 2 1 0 2 2 2 0 UreE urease accessory protein, C-terminal domain FliJ PF02050.11 EPE26433.1 - 4.2 7.4 10.5 0.65 10.0 2.0 2.5 1 1 2 3 3 3 0 Flagellar FliJ protein Glyco_hydro_61 PF03443.9 EPE26434.1 - 1.6e-62 211.1 0.4 2e-62 210.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cellulase PF00150.13 EPE26435.1 - 5.6e-19 68.4 5.1 7.2e-19 68.0 3.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EPE26435.1 - 9.4e-08 31.3 0.1 1.5e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 EPE26435.1 - 0.00044 20.6 0.0 0.00097 19.5 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like DUF2255 PF10012.4 EPE26435.1 - 0.006 16.5 0.5 0.013 15.4 0.3 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2255) Glyco_hydro_10 PF00331.15 EPE26435.1 - 0.0076 15.3 0.2 0.039 12.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 EPE26435.1 - 0.01 14.9 0.5 0.023 13.8 0.1 1.7 2 0 0 2 2 2 0 Beta-galactosidase Lipase_GDSL_2 PF13472.1 EPE26436.1 - 1.6e-08 34.8 0.3 3.2e-08 33.9 0.2 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE26436.1 - 1.5e-06 28.1 4.4 4.7e-06 26.5 3.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EPE26436.1 - 0.038 13.7 0.0 1.7 8.3 0.0 2.2 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family zf-C2H2 PF00096.21 EPE26437.1 - 1.7e-08 34.2 13.2 0.00037 20.6 1.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPE26437.1 - 5.1e-07 29.6 9.7 1.2e-06 28.4 1.0 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPE26437.1 - 0.00011 22.2 11.2 0.013 15.8 1.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EPE26437.1 - 0.019 15.1 3.4 0.036 14.2 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPE26437.1 - 0.063 13.4 0.7 0.063 13.4 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EPE26437.1 - 0.42 10.5 2.5 8.7 6.3 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 EPE26437.1 - 2.8 7.7 7.8 9.2 6.1 0.5 2.3 1 1 1 2 2 2 0 BED zinc finger Lactonase PF10282.4 EPE26439.1 - 3.5e-61 207.2 0.0 4.6e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Lactonase PF10282.4 EPE26440.1 - 1.8e-16 60.1 1.4 2.2e-16 59.8 0.9 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.7 EPE26440.1 - 0.034 14.1 1.1 0.034 14.1 0.7 2.8 1 1 1 2 2 2 0 Putative Ig domain FAD_binding_4 PF01565.18 EPE26441.1 - 7.2e-27 93.5 5.4 1.2e-26 92.8 3.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE26441.1 - 2.8e-14 52.7 0.0 5.6e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 EPE26442.1 - 2.2e-24 85.8 47.4 3e-23 82.1 32.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26442.1 - 1e-07 30.9 11.2 1e-07 30.9 7.8 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter DUF2177 PF09945.4 EPE26442.1 - 0.02 14.8 3.2 0.043 13.8 0.1 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2177) CUE PF02845.11 EPE26442.1 - 0.043 13.3 0.1 0.098 12.1 0.1 1.6 1 0 0 1 1 1 0 CUE domain Ferric_reduct PF01794.14 EPE26444.1 - 9.9e-17 61.1 3.6 9.9e-17 61.1 2.5 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EPE26444.1 - 2.2e-16 60.1 0.0 5.6e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EPE26444.1 - 5.9e-13 48.5 0.0 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EPE26444.1 - 0.00018 22.0 0.7 1.2 9.7 0.0 3.3 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain RNase_PH PF01138.16 EPE26445.1 - 1.5e-21 77.0 0.0 2.4e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EPE26445.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MYT1 PF08474.6 EPE26445.1 - 0.25 10.7 0.9 0.53 9.7 0.1 1.8 1 1 1 2 2 2 0 Myelin transcription factor 1 p450 PF00067.17 EPE26448.1 - 4.6e-37 127.6 0.0 2.7e-36 125.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_42M PF08532.5 EPE26449.1 - 0.041 13.0 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain PPTA PF01239.17 EPE26449.1 - 0.28 10.5 1.4 0.57 9.6 0.3 2.0 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Redoxin PF08534.5 EPE26450.1 - 6.2e-36 123.1 0.0 7.1e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EPE26450.1 - 6.6e-12 45.2 0.0 8.3e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.6 EPE26451.1 - 1.5e-53 180.4 5.8 1.9e-53 180.1 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EPE26451.1 - 7.6e-05 23.0 1.0 0.00012 22.4 0.7 1.3 1 0 0 1 1 1 1 SnoaL-like domain A_deamin PF02137.13 EPE26452.1 - 9.3e-61 206.0 0.0 1.2e-60 205.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain NT-C2 PF10358.4 EPE26453.1 - 1.3e-31 109.0 0.0 2e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Transformer PF06495.6 EPE26453.1 - 5.4 6.8 12.7 12 5.7 8.8 1.6 1 0 0 1 1 1 0 Fruit fly transformer protein zf-RING_3 PF14369.1 EPE26454.1 - 0.14 12.2 2.2 2 8.4 0.1 2.5 2 0 0 2 2 2 0 zinc-finger Sgf11 PF08209.6 EPE26454.1 - 3.5 7.0 5.7 0.45 9.8 0.8 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) PRP21_like_P PF12230.3 EPE26454.1 - 7.7 5.9 8.7 1.7 8.1 0.3 2.5 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Acetyltransf_1 PF00583.19 EPE26455.1 - 3.5e-08 33.3 0.0 5.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE26455.1 - 0.00011 22.2 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_A22B PF04258.8 EPE26456.1 - 8.1e-57 192.9 1.7 6.5e-56 189.9 1.2 2.0 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EPE26456.1 - 0.0031 16.6 16.7 0.027 13.6 7.8 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) Zip PF02535.17 EPE26456.1 - 0.064 12.2 1.1 3.3 6.6 0.0 2.7 3 0 0 3 3 3 0 ZIP Zinc transporter Pro_isomerase PF00160.16 EPE26457.1 - 1.4e-50 171.4 0.0 1.6e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ALO PF04030.9 EPE26458.1 - 1.8e-87 293.2 0.7 2.3e-87 292.8 0.5 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EPE26458.1 - 7.7e-25 86.9 0.0 1.4e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain His_Phos_1 PF00300.17 EPE26459.1 - 3e-30 105.4 0.0 3.7e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TOBE_3 PF12857.2 EPE26460.1 - 0.048 13.5 0.1 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 TOBE-like domain NACHT PF05729.7 EPE26461.1 - 1.5e-11 44.2 0.0 2.9e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 EPE26461.1 - 8.7e-05 22.2 0.0 0.00047 19.8 0.0 2.3 2 1 0 2 2 2 1 PGAP1-like protein AAA_22 PF13401.1 EPE26461.1 - 0.00033 20.8 0.0 0.00096 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.9 EPE26461.1 - 0.00037 19.8 0.0 0.0011 18.3 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPE26461.1 - 0.00052 19.9 0.0 0.0045 16.9 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.1 EPE26461.1 - 0.0097 15.9 0.1 0.059 13.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EPE26461.1 - 0.018 13.8 0.0 0.053 12.3 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EPE26461.1 - 0.024 14.7 0.0 0.081 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 EPE26461.1 - 0.044 12.8 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.4 EPE26461.1 - 0.05 12.5 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 EPE26461.1 - 0.057 13.2 0.1 8.3 6.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 Hexokinase_1 PF00349.16 EPE26462.1 - 3.7e-57 192.9 0.0 5.3e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EPE26462.1 - 4e-57 193.2 0.0 4e-56 189.9 0.0 2.2 1 1 0 1 1 1 1 Hexokinase Fructosamin_kin PF03881.9 EPE26463.1 - 9.4e-31 106.8 0.0 1.1e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase DHQ_synthase PF01761.15 EPE26464.1 - 1.2e-64 217.7 0.0 1.5e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EPE26464.1 - 5.2e-06 25.9 2.4 8.2e-06 25.2 0.0 1.9 1 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EPE26464.1 - 0.04 12.5 3.6 0.24 10.0 0.1 2.1 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase MARVEL PF01284.18 EPE26465.1 - 4.6e-05 23.2 1.5 8.5e-05 22.4 1.0 1.4 1 0 0 1 1 1 1 Membrane-associating domain DUF443 PF04276.7 EPE26465.1 - 0.026 13.9 1.6 0.05 13.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Ank_2 PF12796.2 EPE26466.1 - 3.3e-29 101.0 8.0 3.7e-07 30.4 0.2 7.1 3 1 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE26466.1 - 1.1e-24 86.3 6.2 0.0045 17.4 0.0 8.9 7 2 3 10 10 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE26466.1 - 1.9e-22 78.7 6.6 0.001 19.2 0.1 9.2 5 3 4 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.25 EPE26466.1 - 1.7e-18 65.4 8.7 0.0051 16.5 0.0 9.7 9 0 0 9 9 9 4 Ankyrin repeat Ank_3 PF13606.1 EPE26466.1 - 6.7e-16 56.8 2.9 0.11 12.8 0.0 9.1 9 0 0 9 9 9 4 Ankyrin repeat NACHT PF05729.7 EPE26466.1 - 5.2e-08 32.7 0.1 3e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EPE26466.1 - 3.3e-05 24.0 0.2 0.00039 20.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPE26466.1 - 0.00013 21.6 0.0 0.00073 19.2 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain DUF2448 PF10476.4 EPE26466.1 - 0.00031 20.3 0.5 0.017 14.6 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2448) AAA_16 PF13191.1 EPE26466.1 - 0.00036 20.5 0.4 0.0014 18.6 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EPE26466.1 - 0.012 15.5 0.0 1.5 8.7 0.0 3.2 1 1 0 1 1 1 0 AAA domain DUF336 PF03928.9 EPE26467.1 - 7.6e-20 71.0 0.0 1e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF336) HET PF06985.6 EPE26469.1 - 9.4e-16 58.2 8.1 3.1e-13 50.0 1.7 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RNA_ligase PF09414.5 EPE26470.1 - 6.3e-05 22.8 0.0 0.00017 21.4 0.0 1.7 2 0 0 2 2 2 1 RNA ligase AAA_22 PF13401.1 EPE26471.1 - 6.6e-05 23.0 0.0 0.00061 19.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain TPR_12 PF13424.1 EPE26471.1 - 0.001 18.9 5.6 0.18 11.7 0.3 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ZZ PF00569.12 EPE26471.1 - 0.0024 17.3 3.5 0.0054 16.2 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type AAA_16 PF13191.1 EPE26471.1 - 0.01 15.8 0.2 0.12 12.3 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.7 EPE26471.1 - 0.023 14.3 0.0 0.062 12.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EPE26471.1 - 0.024 14.8 0.0 0.1 12.8 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EPE26471.1 - 0.027 14.6 0.0 0.094 12.8 0.0 2.0 1 0 0 1 1 1 0 RNA helicase TPR_7 PF13176.1 EPE26471.1 - 0.071 12.9 0.4 2.5 8.1 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat HRXXH PF13933.1 EPE26472.1 - 6.3e-08 32.3 0.1 2.8e-05 23.6 0.1 2.2 2 0 0 2 2 2 2 Putative peptidase family Peptidase_M35 PF02102.10 EPE26472.1 - 0.15 10.6 0.1 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family OPT PF03169.10 EPE26473.1 - 4.3e-172 573.8 64.4 4.9e-172 573.6 44.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF885 PF05960.6 EPE26474.1 - 1.7e-52 179.3 0.0 2.9e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) SLS PF14611.1 EPE26475.1 - 3.4e-24 85.4 0.5 6.4e-24 84.5 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator MAGE PF01454.14 EPE26476.1 - 4.6e-25 88.1 0.0 1.5e-24 86.3 0.0 1.8 1 1 0 1 1 1 1 MAGE family CDC27 PF09507.5 EPE26476.1 - 2.3 7.3 9.1 4.3 6.4 6.3 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SF3b10 PF07189.6 EPE26477.1 - 4.7e-31 106.4 0.0 5.5e-31 106.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) zf-MYND PF01753.13 EPE26478.1 - 0.97 9.3 21.2 0.07 13.0 2.5 3.5 4 0 0 4 4 4 0 MYND finger zf-Mss51 PF13824.1 EPE26478.1 - 4.4 7.2 12.4 2.2 8.1 2.1 3.2 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Peptidase_S8 PF00082.17 EPE26481.1 - 1.1e-17 64.1 0.0 1.3e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 Subtilase family CorA PF01544.13 EPE26482.1 - 1.7e-13 50.2 0.0 1.3e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Cytochrom_B561 PF03188.11 EPE26485.1 - 1.4e-06 28.1 5.4 1.4e-06 28.1 3.7 1.8 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 Peptidase_C15 PF01470.12 EPE26485.1 - 0.051 13.3 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 Pyroglutamyl peptidase Ank PF00023.25 EPE26486.1 - 3.5e-23 80.1 3.1 1.6e-07 30.7 0.2 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EPE26486.1 - 2.9e-21 75.6 0.7 8.2e-21 74.1 0.6 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPE26486.1 - 7.9e-20 68.9 0.8 2.9e-05 23.8 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EPE26486.1 - 7.9e-18 64.4 0.3 1.5e-11 44.4 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE26486.1 - 1.7e-17 62.9 6.8 2.2e-09 37.2 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF3984 PF13136.1 EPE26486.1 - 0.032 13.4 0.2 0.032 13.4 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) DUF3328 PF11807.3 EPE26487.1 - 7.8e-42 143.3 0.3 8.7e-42 143.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cu-oxidase_3 PF07732.10 EPE26488.1 - 4.7e-39 132.7 4.4 4.3e-38 129.6 0.8 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPE26488.1 - 4.7e-36 123.3 3.5 8.6e-34 116.0 0.0 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EPE26488.1 - 1.1e-13 51.4 0.1 9.9e-10 38.5 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase YfhE PF14152.1 EPE26489.1 - 0.064 13.1 0.3 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 YfhE-like protein DUF3328 PF11807.3 EPE26489.1 - 0.15 11.7 5.5 0.38 10.4 3.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) DUF4446 PF14584.1 EPE26490.1 - 0.0004 20.2 8.5 0.18 11.6 0.4 4.4 1 1 3 5 5 5 3 Protein of unknown function (DUF4446) RBD PF02196.10 EPE26490.1 - 0.0068 16.1 4.0 27 4.6 0.0 6.0 4 2 4 9 9 9 1 Raf-like Ras-binding domain Bacillus_PapR PF05968.6 EPE26490.1 - 0.43 10.6 4.2 53 4.0 0.0 4.8 6 2 1 7 7 7 0 Bacillus PapR protein RNA_replicase_B PF03431.8 EPE26490.1 - 0.94 7.6 5.3 4.7 5.2 0.2 3.0 1 1 3 4 4 4 0 RNA replicase, beta-chain PKK PF12474.3 EPE26490.1 - 2.1 8.0 5.1 4.2 7.0 0.2 3.0 2 2 1 3 3 3 0 Polo kinase kinase DUF3328 PF11807.3 EPE26491.1 - 2.7e-35 122.0 0.1 3.4e-35 121.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pam17 PF08566.5 EPE26492.1 - 0.0015 18.2 0.0 0.0019 17.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Dioxygenase_C PF00775.16 EPE26493.1 - 1.7e-52 177.3 0.0 2.4e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EPE26493.1 - 1.3e-14 53.9 0.0 2.3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EPE26493.1 - 0.0097 15.9 0.0 0.025 14.6 0.0 1.7 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain GTP_EFTU PF00009.22 EPE26494.1 - 6.1e-57 192.0 0.0 1.1e-56 191.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPE26494.1 - 1.4e-34 118.2 0.1 3.3e-34 117.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPE26494.1 - 3.3e-15 55.9 2.7 3.3e-15 55.9 1.9 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPE26494.1 - 0.00049 20.0 0.2 0.0019 18.1 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EPE26494.1 - 0.0053 16.3 1.0 0.0053 16.3 0.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 EPE26494.1 - 0.01 15.7 0.4 0.026 14.4 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain HET PF06985.6 EPE26495.1 - 9e-24 84.2 0.0 1.6e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lipase_3 PF01764.20 EPE26496.1 - 3.5e-14 52.6 0.0 3.8e-13 49.2 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EPE26496.1 - 0.0018 18.2 0.1 0.0038 17.1 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_7 PF13508.1 EPE26497.1 - 6.9e-11 42.1 0.2 9.6e-11 41.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE26497.1 - 1.6e-10 40.9 0.1 2.3e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EPE26497.1 - 0.0015 18.3 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_tranf_2_4 PF13704.1 EPE26498.1 - 0.12 12.6 0.2 2.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Peptidase_M14 PF00246.19 EPE26499.1 - 9.1e-75 251.8 0.1 1.1e-74 251.5 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EPE26499.1 - 1.7e-06 27.5 0.0 4.2e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Methyltransf_23 PF13489.1 EPE26500.1 - 1.3e-11 44.4 0.0 2.4e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE26500.1 - 2.3e-07 30.5 0.0 3.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE26500.1 - 3.8e-07 30.5 0.0 1.3e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE26500.1 - 4.1e-07 30.5 0.0 7.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE26500.1 - 2.1e-06 27.0 0.0 0.00016 20.8 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EPE26500.1 - 3.9e-06 27.2 0.0 1.7e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE26500.1 - 0.00015 22.0 0.0 0.00039 20.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE26500.1 - 0.025 14.6 0.0 0.044 13.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 EPE26502.1 - 2.7e-80 269.8 0.0 3.9e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPE26502.1 - 2.9e-63 213.0 0.0 4.6e-61 205.8 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EPE26502.1 - 5.8e-38 130.4 3.1 4.9e-35 120.9 1.1 3.2 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 EPE26502.1 - 7.2e-22 77.9 2.6 4.9e-18 65.4 1.2 2.7 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EPE26502.1 - 1.2e-21 77.5 0.3 2.2e-21 76.7 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPE26502.1 - 1.1e-18 67.6 0.1 3e-09 36.6 0.0 3.0 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EPE26502.1 - 7.3e-11 42.1 0.0 1.8e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EPE26502.1 - 3.8e-10 38.9 0.1 1.7e-06 26.9 0.0 2.8 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EPE26502.1 - 3e-09 37.6 0.9 9.1e-08 32.9 0.1 3.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 EPE26502.1 - 1.2e-07 30.9 1.2 0.0002 20.3 0.1 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EPE26502.1 - 8.1e-07 29.2 2.0 9.1e-05 22.5 0.5 3.1 2 1 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EPE26502.1 - 7.9e-06 24.9 0.1 0.0057 15.5 0.0 3.3 3 0 0 3 3 3 1 RmlD substrate binding domain Saccharop_dh PF03435.13 EPE26502.1 - 0.00039 19.5 0.2 0.00068 18.7 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DFP PF04127.10 EPE26502.1 - 0.0041 16.7 0.5 0.0098 15.5 0.4 1.6 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 EPE26502.1 - 0.0093 15.7 0.7 0.023 14.5 0.5 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EPE26502.1 - 0.013 14.6 0.0 0.036 13.1 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain p450 PF00067.17 EPE26503.1 - 1e-32 113.2 0.0 1.3e-28 99.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Malic_M PF03949.10 EPE26504.1 - 6.5e-15 55.3 0.0 8.4e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Octopine_DH PF02317.12 EPE26504.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Glyco_hydro_18 PF00704.23 EPE26505.1 - 3.7e-55 187.7 2.3 4.4e-55 187.5 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EPE26505.1 - 0.03 14.2 20.9 0.03 14.2 14.5 2.4 2 1 0 2 2 2 0 Chitin recognition protein Peptidase_S8 PF00082.17 EPE26506.1 - 8.9e-42 143.1 7.0 1.6e-41 142.3 4.8 1.5 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EPE26506.1 - 5.5e-10 39.6 0.0 5.9e-09 36.3 0.1 2.4 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 EPE26506.1 - 1.1e-09 37.8 0.0 3.6e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 PA domain DUF4363 PF14276.1 EPE26507.1 - 0.0025 17.5 22.8 0.44 10.2 0.3 9.2 5 4 7 12 12 12 3 Domain of unknown function (DUF4363) TAFH PF07531.9 EPE26507.1 - 0.031 13.9 2.0 0.34 10.5 0.1 3.6 3 0 0 3 3 3 0 NHR1 homology to TAF Trns_repr_metal PF02583.12 EPE26507.1 - 0.54 10.4 12.0 6.4 7.0 0.2 6.3 6 0 0 6 6 6 0 Metal-sensitive transcriptional repressor Sel1 PF08238.7 EPE26508.1 - 5.4e-40 134.9 25.5 7.7e-07 29.5 0.2 8.0 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.1 EPE26508.1 - 1 9.9 0.0 1 9.9 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat CBP4 PF07960.6 EPE26509.1 - 1.7e-32 111.7 0.4 2.1e-32 111.4 0.3 1.1 1 0 0 1 1 1 1 CBP4 Seryl_tRNA_N PF02403.17 EPE26509.1 - 0.022 14.7 4.4 0.036 14.0 3.1 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Aldedh PF00171.17 EPE26509.1 - 0.1 10.9 0.2 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Pkinase PF00069.20 EPE26510.1 - 4.1e-17 62.2 0.0 1.5e-16 60.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE26510.1 - 9.7e-07 28.1 0.2 1.5e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EPE26510.1 - 0.00084 18.7 0.1 0.0014 17.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EPE26510.1 - 0.027 13.4 0.0 0.41 9.5 0.0 2.5 3 0 0 3 3 3 0 Kinase-like Reductase_C PF14759.1 EPE26510.1 - 0.12 12.6 0.1 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 Reductase C-terminal GMC_oxred_N PF00732.14 EPE26513.1 - 4.8e-35 121.1 0.0 1.3e-31 109.9 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE26513.1 - 6.7e-28 97.7 0.0 1.1e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 EPE26513.1 - 0.00027 20.8 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE26513.1 - 0.00057 19.8 0.1 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE26513.1 - 0.0043 16.0 0.0 0.0092 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE26513.1 - 0.0047 15.9 0.0 0.0066 15.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPE26513.1 - 0.013 14.3 0.1 0.036 12.9 0.1 1.7 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EPE26513.1 - 0.014 15.4 0.0 0.17 11.8 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE26513.1 - 0.073 11.5 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein MPC PF03650.8 EPE26514.1 - 1.7e-42 144.1 0.4 1.7e-42 144.1 0.3 1.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0041) L51_S25_CI-B8 PF05047.11 EPE26515.1 - 1.7e-11 43.6 0.0 2.1e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain NifW PF03206.9 EPE26515.1 - 0.087 12.9 0.1 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Nitrogen fixation protein NifW Glyco_hydro_19 PF00182.14 EPE26516.1 - 0.046 13.3 0.1 0.064 12.9 0.1 1.4 1 0 0 1 1 1 0 Chitinase class I Ferritin_2 PF13668.1 EPE26517.1 - 3.2e-14 53.0 0.0 5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain CHZ PF09649.5 EPE26518.1 - 0.00085 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Histone chaperone domain CHZ adh_short PF00106.20 EPE26519.1 - 2e-17 63.6 0.0 3.1e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE26519.1 - 2.3e-10 40.6 0.0 3.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE26519.1 - 4.4e-09 36.2 0.0 8.3e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EPE26519.1 - 0.00017 21.2 0.9 0.00021 21.0 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EPE26519.1 - 0.0067 15.3 0.1 0.0097 14.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EPE26519.1 - 0.081 13.0 0.4 0.15 12.1 0.3 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UPF0051 PF01458.12 EPE26519.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) Pkinase PF00069.20 EPE26520.1 - 5.1e-18 65.1 0.0 1.1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE26520.1 - 9.6e-08 31.4 0.0 1.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPE26520.1 - 0.0038 16.9 0.1 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1996 PF09362.5 EPE26521.1 - 1.9e-85 286.3 1.0 2.6e-85 285.8 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) APH PF01636.18 EPE26521.1 - 1.3e-11 44.6 0.0 3.7e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE26521.1 - 0.00083 18.9 0.1 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3091 PF11291.3 EPE26521.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) Oxysterol_BP PF01237.13 EPE26524.1 - 1.4e-134 448.1 0.2 4.5e-134 446.4 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EPE26524.1 - 4.5e-18 65.3 0.0 1.8e-11 44.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE26524.1 - 2.5e-16 59.6 0.2 1.8e-09 37.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE26524.1 - 4.7e-16 58.4 0.9 1.6e-09 37.6 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EPE26524.1 - 1.5e-15 56.0 0.2 8.1e-05 22.2 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EPE26524.1 - 3.7e-13 48.3 0.1 0.0011 19.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.24 EPE26524.1 - 8.7e-10 38.7 0.2 1.7e-09 37.7 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EPE26524.1 - 4.3e-06 26.7 0.5 9.7e-06 25.5 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain BAF1_ABF1 PF04684.8 EPE26525.1 - 0.005 15.7 1.6 0.0064 15.4 1.1 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DZR PF12773.2 EPE26525.1 - 0.13 12.0 15.7 0.14 11.9 1.5 3.6 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 EPE26525.1 - 7.4 6.4 11.5 0.6 9.9 0.3 3.5 2 1 1 3 3 3 0 zinc-ribbons TPR_12 PF13424.1 EPE26527.1 - 1e-10 41.3 7.0 0.08 12.8 0.0 6.1 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPE26527.1 - 5.1e-07 29.9 0.9 2.8 8.3 0.0 5.8 4 1 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EPE26527.1 - 0.00034 20.6 11.1 0.0044 17.1 0.0 4.6 4 1 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EPE26527.1 - 0.006 17.1 0.8 18 6.2 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPE26527.1 - 0.0063 17.1 1.0 5.3 7.8 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPE26527.1 - 0.045 14.2 4.6 3 8.5 0.0 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPE26527.1 - 0.052 13.5 3.9 20 5.2 0.2 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Peripla_BP_4 PF13407.1 EPE26527.1 - 0.065 12.5 0.1 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Periplasmic binding protein domain TPR_11 PF13414.1 EPE26527.1 - 0.2 11.3 8.4 9.3 5.9 0.1 4.3 3 2 2 5 5 4 0 TPR repeat TPR_7 PF13176.1 EPE26527.1 - 0.21 11.4 5.6 8.9 6.3 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPE26527.1 - 0.96 9.5 12.3 0.89 9.6 0.1 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF4064 PF13273.1 EPE26528.1 - 0.12 12.4 3.9 0.44 10.6 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) CoA_binding_3 PF13727.1 EPE26528.1 - 1.4 8.7 9.9 0.049 13.4 1.5 2.2 1 1 1 2 2 2 0 CoA-binding domain DUF3328 PF11807.3 EPE26531.1 - 4.8e-32 111.3 0.4 6.4e-32 111.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) p450 PF00067.17 EPE26532.1 - 9.7e-43 146.3 0.0 1.3e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 G-gamma PF00631.17 EPE26533.1 - 0.069 12.9 1.7 0.23 11.2 1.1 1.9 1 0 0 1 1 1 0 GGL domain NPV_P10 PF05531.7 EPE26533.1 - 0.098 12.9 0.9 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.6 EPE26533.1 - 0.32 8.4 2.1 0.49 7.8 0.0 1.9 1 1 1 2 2 2 0 Prominin DUF4404 PF14357.1 EPE26533.1 - 3 8.3 6.3 3.9 7.9 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) C2 PF00168.25 EPE26535.1 - 1.1e-14 54.0 0.0 4.8e-12 45.5 0.1 2.4 2 0 0 2 2 2 2 C2 domain HET PF06985.6 EPE26537.1 - 5.3e-24 84.9 0.2 1.1e-23 83.9 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glycos_transf_1 PF00534.15 EPE26539.1 - 2.1e-19 69.6 0.0 4.2e-19 68.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPE26539.1 - 1.1e-09 38.5 0.0 2.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EPE26539.1 - 0.014 15.6 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_20 PF00982.16 EPE26539.1 - 0.28 9.6 0.0 0.49 8.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 20 zf-C2H2 PF00096.21 EPE26541.1 - 2.7e-05 24.2 14.6 8.8e-05 22.6 0.3 5.0 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EPE26541.1 - 0.012 15.7 1.6 0.29 11.2 0.2 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EPE26541.1 - 0.05 13.9 0.2 0.05 13.9 0.1 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger IBR PF01485.16 EPE26541.1 - 0.12 12.2 5.0 0.46 10.4 3.4 2.0 1 0 0 1 1 1 0 IBR domain 4HBT_3 PF13622.1 EPE26542.1 - 4.3e-34 118.4 0.2 7e-34 117.7 0.1 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EPE26542.1 - 5.6e-11 42.1 0.0 0.00091 18.8 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase Zn_clus PF00172.13 EPE26543.1 - 4.8 7.1 8.7 13 5.8 6.0 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tn7_Tnp_TnsA_C PF08721.6 EPE26544.1 - 0.084 12.9 0.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 TnsA endonuclease C terminal Zn_clus PF00172.13 EPE26545.1 - 0.082 12.8 3.7 0.17 11.8 2.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro-kuma_activ PF09286.6 EPE26547.1 - 5.2e-44 149.7 0.2 9.9e-44 148.8 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF2514 PF10721.4 EPE26548.1 - 1.7 8.3 22.1 2.3 7.9 15.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) GST_N_2 PF13409.1 EPE26549.1 - 8e-16 57.8 0.0 1.7e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE26549.1 - 5.9e-13 48.4 0.0 1.2e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPE26549.1 - 6.6e-05 23.3 0.0 0.00013 22.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPE26549.1 - 0.012 15.8 0.0 0.078 13.2 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Cyclin PF08613.6 EPE26550.1 - 0.1 12.9 0.1 0.14 12.5 0.1 1.2 1 0 0 1 1 1 0 Cyclin Cu_bind_like PF02298.12 EPE26551.1 - 0.017 14.8 1.0 0.15 11.8 0.7 2.2 1 1 0 1 1 1 0 Plastocyanin-like domain QRPTase_C PF01729.14 EPE26552.1 - 9.8e-55 184.6 0.1 1.2e-54 184.3 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EPE26552.1 - 1.5e-22 79.2 0.0 4.2e-22 77.7 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.17 EPE26552.1 - 0.0046 16.5 0.1 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase IGPS PF00218.16 EPE26552.1 - 0.032 13.3 0.2 0.086 11.8 0.1 1.6 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF1341 PF07071.6 EPE26552.1 - 0.067 12.7 0.1 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1341) PHB_depo_C PF06850.6 EPE26552.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 PHB de-polymerase C-terminus Methyltransf_11 PF08241.7 EPE26553.1 - 2e-27 95.5 0.0 1.1e-16 61.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EPE26553.1 - 4.9e-22 78.3 0.0 3.1e-14 52.9 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EPE26553.1 - 5.9e-16 58.4 0.1 5.1e-11 42.3 0.0 3.2 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EPE26553.1 - 6.6e-16 58.8 0.0 2.3e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EPE26553.1 - 1.5e-12 47.8 0.0 2e-06 28.2 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EPE26553.1 - 1.6e-12 47.6 0.0 1.7e-07 31.5 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.13 EPE26553.1 - 9.5e-11 41.2 0.0 8.2e-09 34.9 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EPE26553.1 - 3.3e-10 39.6 0.0 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EPE26553.1 - 4.8e-06 26.5 0.1 0.0014 18.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPE26553.1 - 1.5e-05 24.3 0.0 0.041 13.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain NodS PF05401.6 EPE26553.1 - 0.0012 18.2 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) GidB PF02527.10 EPE26553.1 - 0.0017 17.4 0.2 0.033 13.3 0.0 2.2 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G DREV PF05219.7 EPE26553.1 - 0.0037 16.1 0.0 0.01 14.7 0.0 1.7 2 0 0 2 2 2 1 DREV methyltransferase CheR PF01739.13 EPE26553.1 - 0.0042 16.4 0.0 1.7 7.8 0.0 3.3 3 0 0 3 3 3 1 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.1 EPE26553.1 - 0.013 15.2 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.13 EPE26553.1 - 0.031 13.4 0.1 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_9 PF08003.6 EPE26553.1 - 0.04 12.6 0.0 0.97 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) PrmA PF06325.8 EPE26553.1 - 0.045 12.8 0.0 4 6.4 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 EPE26553.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 YkyA PF10368.4 EPE26555.1 - 0.21 10.8 0.2 0.33 10.2 0.1 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Peroxidase_2 PF01328.12 EPE26557.1 - 2.4e-19 69.1 0.2 5.1e-19 68.0 0.0 1.6 2 0 0 2 2 2 1 Peroxidase, family 2 Dabb PF07876.7 EPE26558.1 - 8.2e-09 35.7 0.0 1.7e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Pyrid_oxidase_2 PF13883.1 EPE26558.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DLH PF01738.13 EPE26559.1 - 1.9e-09 37.1 0.0 2.3e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPE26559.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family SH3_9 PF14604.1 EPE26560.1 - 3e-10 39.5 0.3 5.5e-10 38.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPE26560.1 - 8.1e-10 37.9 0.1 1.5e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPE26560.1 - 4.4e-08 32.4 0.3 1.6e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain YcaO PF02624.11 EPE26560.1 - 0.02 14.3 0.1 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 YcaO-like family Acetyltransf_7 PF13508.1 EPE26563.1 - 0.0013 18.8 0.0 0.0044 17.1 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 EPE26563.1 - 0.018 15.3 0.0 0.045 14.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE26563.1 - 0.1 13.1 0.0 0.29 11.7 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE26563.1 - 0.13 12.5 0.0 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Nop14 PF04147.7 EPE26563.1 - 0.55 8.0 10.5 0.95 7.3 7.3 1.3 1 0 0 1 1 1 0 Nop14-like family AMP-binding PF00501.23 EPE26566.1 - 3.3e-86 289.3 0.0 4.1e-82 275.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EPE26566.1 - 1.3e-66 224.5 0.0 2.8e-43 147.8 0.0 3.0 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EPE26566.1 - 2.2e-21 75.8 0.2 6.4e-12 45.5 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPE26566.1 - 3.9e-06 27.7 0.0 0.017 16.0 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain ABC_tran PF00005.22 EPE26567.1 - 1.5e-42 145.1 0.0 4.1e-21 75.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPE26567.1 - 7.7e-31 107.5 39.6 8e-26 91.0 14.9 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EPE26567.1 - 7.6e-11 42.5 0.0 0.026 14.5 0.0 4.2 2 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 EPE26567.1 - 1.1e-06 28.0 3.6 0.13 11.4 0.1 4.4 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPE26567.1 - 1.4e-05 24.4 0.4 0.22 11.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EPE26567.1 - 6.5e-05 23.7 0.0 0.34 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPE26567.1 - 0.00017 21.6 0.2 0.44 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EPE26567.1 - 0.0011 18.9 0.0 0.27 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE26567.1 - 0.0011 19.1 0.0 0.29 11.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPE26567.1 - 0.0014 18.9 1.7 1.2 9.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 EPE26567.1 - 0.0027 17.4 0.2 0.99 9.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EPE26567.1 - 0.0036 16.4 0.2 2.6 7.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EPE26567.1 - 0.0082 15.6 0.3 7.6 5.8 0.0 3.4 3 0 0 3 3 3 0 AAA-like domain AAA_25 PF13481.1 EPE26567.1 - 0.019 14.3 0.3 4.7 6.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 EPE26567.1 - 0.019 15.4 0.0 0.4 11.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 EPE26567.1 - 0.044 12.6 0.1 1.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EPE26567.1 - 0.074 13.0 0.2 11 5.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EPE26567.1 - 0.13 11.7 0.0 0.54 9.6 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EPE26567.1 - 0.13 12.5 0.7 9.8 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EPE26567.1 - 0.13 12.0 0.2 0.48 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 3Beta_HSD PF01073.14 EPE26568.1 - 3.4e-11 42.3 0.3 1e-10 40.8 0.2 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPE26568.1 - 1.9e-08 33.5 0.4 7.8e-07 28.2 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EPE26568.1 - 7.9e-08 32.5 0.1 5.7e-07 29.7 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE26568.1 - 1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPE26568.1 - 2e-06 27.2 0.3 9.2e-06 25.0 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EPE26568.1 - 0.021 14.5 0.2 3.9 7.0 0.0 3.1 3 0 0 3 3 3 0 KR domain adh_short PF00106.20 EPE26568.1 - 0.022 14.6 1.4 1.2 8.9 0.6 3.1 2 1 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPE26568.1 - 0.049 12.5 0.1 0.089 11.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans_2 PF11951.3 EPE26569.1 - 0.00068 18.3 0.1 0.00091 17.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MmgE_PrpD PF03972.9 EPE26570.1 - 1.1e-152 508.3 0.0 1.2e-152 508.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family EAF PF09816.4 EPE26571.1 - 1.8e-19 69.6 0.4 5.6e-19 68.1 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor PAXIP1_C PF15364.1 EPE26571.1 - 0.0023 17.8 5.0 0.0023 17.8 3.4 2.8 2 1 0 2 2 2 1 PAXIP1-associated-protein-1 C term PTIP binding protein Cellulase PF00150.13 EPE26572.1 - 3e-50 171.0 1.1 3.5e-50 170.7 0.8 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pyr_redox_3 PF13738.1 EPE26574.1 - 2.5e-20 73.3 0.0 4e-19 69.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE26574.1 - 9.9e-10 37.2 0.0 2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPE26574.1 - 7e-09 35.0 0.0 6.7e-06 25.2 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPE26574.1 - 4.2e-07 29.8 0.1 0.0019 17.9 0.0 3.2 2 2 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.12 EPE26574.1 - 2e-06 27.0 0.0 0.023 13.8 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 EPE26574.1 - 1.9e-05 24.6 0.0 0.055 13.3 0.0 3.5 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE26574.1 - 0.00035 19.5 0.1 0.011 14.6 0.0 2.6 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE26574.1 - 0.00052 19.9 0.0 0.008 16.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPE26574.1 - 0.0051 17.1 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE26574.1 - 0.035 12.5 0.0 5.7 5.3 0.0 3.2 4 0 0 4 4 4 0 HI0933-like protein GIDA PF01134.17 EPE26574.1 - 0.096 11.5 0.0 0.33 9.7 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EPE26574.1 - 0.22 10.5 0.2 1.5 7.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain GMC_oxred_C PF05199.8 EPE26576.1 - 2.1e-32 112.3 0.0 3.8e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EPE26576.1 - 1.4e-28 99.9 0.0 6.6e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 EPE26576.1 - 0.0014 18.5 0.1 0.0038 17.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE26576.1 - 0.0031 17.4 0.1 0.033 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE26576.1 - 0.012 14.4 0.0 0.035 12.9 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EPE26576.1 - 0.017 13.6 0.0 0.025 13.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 EPE26576.1 - 0.018 13.9 0.0 0.062 12.1 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE26576.1 - 0.03 13.2 0.1 0.045 12.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EPE26576.1 - 0.036 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EPE26576.1 - 0.08 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EPE26576.1 - 0.12 11.4 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EPE26576.1 - 0.14 10.9 0.2 0.55 9.0 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A p450 PF00067.17 EPE26577.1 - 1.7e-49 168.6 0.0 2.6e-48 164.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EPE26579.1 - 1e-14 54.7 0.7 2.4e-14 53.6 0.1 1.9 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EPE26579.1 - 3.7e-05 23.4 0.1 9.3e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE26579.1 - 0.00033 20.4 0.1 0.00075 19.3 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPE26579.1 - 0.0028 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family IBR PF01485.16 EPE26581.1 - 4.3e-11 42.5 18.2 4.6e-09 36.0 3.5 4.1 3 1 1 4 4 4 2 IBR domain DHquinase_II PF01220.14 EPE26582.1 - 7.5e-60 200.2 0.1 8.5e-60 200.1 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II MTS PF05175.9 EPE26582.1 - 0.1 12.0 0.1 0.4 10.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EPE26583.1 - 2.6e-11 43.8 0.0 4.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE26583.1 - 4.3e-09 36.7 0.0 6.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE26583.1 - 2.1e-07 31.5 0.0 3.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE26583.1 - 2.4e-07 30.6 0.0 5.4e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE26583.1 - 1.5e-06 27.5 0.0 5.8e-06 25.5 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPE26583.1 - 1.6e-06 28.3 0.0 2.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE26583.1 - 6.2e-06 25.8 0.0 9.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF2806 PF10987.3 EPE26583.1 - 0.11 12.0 0.4 5.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2806) Ank_2 PF12796.2 EPE26584.1 - 3.1e-12 46.6 0.1 7.8e-11 42.1 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE26584.1 - 3.5e-08 33.7 1.1 8e-06 26.2 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EPE26584.1 - 4.4e-08 32.5 4.9 4.8e-06 26.1 0.3 4.6 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 EPE26584.1 - 1.8e-07 31.1 1.4 0.00013 22.1 0.4 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NACHT PF05729.7 EPE26584.1 - 3.2e-07 30.1 0.1 3e-06 26.9 0.0 2.5 2 1 1 3 3 3 1 NACHT domain Ank_3 PF13606.1 EPE26584.1 - 5.4e-06 26.1 0.0 0.0002 21.2 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat AAA_16 PF13191.1 EPE26584.1 - 4.4e-05 23.5 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NAC PF01849.13 EPE26587.1 - 1.2e-20 72.8 0.2 1.2e-20 72.8 0.1 1.5 2 0 0 2 2 2 1 NAC domain AdoMet_MTase PF07757.8 EPE26588.1 - 2.1e-39 134.1 0.0 3.1e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 EPE26588.1 - 0.00011 21.8 0.0 0.0003 20.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE26588.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE26588.1 - 0.037 14.6 0.0 0.068 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EPE26588.1 - 0.15 11.4 0.0 0.48 9.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Ribosomal_L24e PF01246.15 EPE26589.1 - 5.2e-30 103.1 0.4 5.2e-30 103.1 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e Abhydrolase_2 PF02230.11 EPE26590.1 - 3.3e-57 193.3 0.0 3.9e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EPE26590.1 - 4.2e-09 36.3 0.0 7.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE26590.1 - 5.7e-05 22.4 0.5 0.00042 19.6 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EPE26590.1 - 9.1e-05 22.4 0.1 0.012 15.5 0.1 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPE26590.1 - 0.00021 20.8 0.0 0.0026 17.2 0.0 2.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EPE26590.1 - 0.0018 17.8 0.0 1.5 8.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 EPE26590.1 - 0.0025 17.1 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydro_lipase PF04083.11 EPE26590.1 - 0.023 14.0 0.1 0.32 10.3 0.0 2.3 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF1581 PF07619.6 EPE26590.1 - 0.026 14.4 0.1 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) Lipase_3 PF01764.20 EPE26590.1 - 0.058 13.0 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.17 EPE26590.1 - 0.08 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase IMD PF08397.6 EPE26591.1 - 0.001 18.4 0.9 0.0024 17.1 0.2 1.7 2 0 0 2 2 2 1 IRSp53/MIM homology domain Seryl_tRNA_N PF02403.17 EPE26591.1 - 0.043 13.8 0.7 0.16 11.9 0.5 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CytochromB561_N PF09786.4 EPE26592.1 - 2.4 6.4 5.3 0.31 9.4 0.1 1.8 2 0 0 2 2 2 0 Cytochrome B561, N terminal DUF1687 PF07955.6 EPE26593.1 - 4.7e-18 65.4 3.3 2.4e-17 63.1 2.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 EPE26593.1 - 0.073 13.1 0.1 1.4 9.0 0.0 2.4 1 1 1 2 2 2 0 ArsC family AIF_C PF14721.1 EPE26593.1 - 0.1 12.8 0.2 0.17 12.1 0.1 1.4 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RRM_6 PF14259.1 EPE26594.1 - 8.3e-07 28.8 0.0 1.7e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE26594.1 - 3.9e-06 26.4 0.0 8.7e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE26594.1 - 0.0039 17.0 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GST_N_2 PF13409.1 EPE26596.1 - 1.7e-12 47.1 0.0 3.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPE26596.1 - 3.2e-11 43.2 0.0 6.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPE26596.1 - 4.1e-10 39.7 0.0 9e-10 38.6 0.0 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPE26596.1 - 2.5e-08 33.7 0.1 3.9e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPE26596.1 - 0.00042 20.1 0.0 0.00092 19.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPE26596.1 - 0.039 14.4 0.1 0.062 13.7 0.1 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box PF00646.28 EPE26597.1 - 5.3e-08 32.3 0.0 1.6e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE26597.1 - 4.6e-07 29.4 0.3 1.5e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 F-box-like Zn_clus PF00172.13 EPE26598.1 - 3.6e-09 36.3 7.1 5.5e-09 35.7 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mpv17_PMP22 PF04117.7 EPE26599.1 - 2.1e-15 56.0 0.4 2.1e-15 56.0 0.3 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Mucin PF01456.12 EPE26600.1 - 0.041 13.6 19.4 0.065 13.0 13.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Zn_clus PF00172.13 EPE26601.1 - 0.0068 16.2 14.1 0.011 15.5 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE26602.1 - 1.9e-40 138.6 46.5 1.9e-40 138.6 32.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE26602.1 - 3.3e-14 52.0 15.0 3.3e-14 52.0 10.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2919 PF11143.3 EPE26602.1 - 0.055 13.2 0.5 0.055 13.2 0.3 3.2 3 2 0 3 3 3 0 Protein of unknown function (DUF2919) DUF3918 PF13056.1 EPE26602.1 - 1.9 7.9 5.7 0.27 10.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Thr_synth_N PF14821.1 EPE26603.1 - 2e-30 104.6 0.0 4.8e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EPE26603.1 - 8.2e-20 71.2 0.0 6.3e-19 68.3 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DOMON PF03351.12 EPE26604.1 - 0.0048 16.8 0.1 0.0068 16.3 0.1 1.4 1 0 0 1 1 1 1 DOMON domain DUF1996 PF09362.5 EPE26605.1 - 4.4e-76 255.6 1.0 5.7e-76 255.2 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Smg4_UPF3 PF03467.10 EPE26606.1 - 3.7e-26 92.1 0.0 1.4e-25 90.3 0.0 1.9 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_6 PF14259.1 EPE26606.1 - 2.2e-06 27.5 0.6 8e-05 22.5 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE26606.1 - 8.1e-06 25.3 0.0 7e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 EPE26607.1 - 1e-37 129.5 0.1 1.7e-32 112.4 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPE26607.1 - 0.035 13.9 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain DUF3459 PF11941.3 EPE26608.1 - 0.016 15.3 0.1 0.19 11.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3459) Pyridox_oxidase PF01243.15 EPE26608.1 - 0.03 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase IncA PF04156.9 EPE26609.1 - 0.0018 17.8 4.6 0.0024 17.5 3.2 1.1 1 0 0 1 1 1 1 IncA protein YscO PF07321.7 EPE26609.1 - 0.0029 17.4 7.9 0.0041 16.9 5.5 1.1 1 0 0 1 1 1 1 Type III secretion protein YscO LCD1 PF09798.4 EPE26609.1 - 0.011 13.7 5.7 0.014 13.4 4.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein FliJ PF02050.11 EPE26609.1 - 0.013 15.5 6.2 0.017 15.1 4.3 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein GAS PF13851.1 EPE26609.1 - 0.019 14.1 10.7 0.026 13.7 7.4 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EPE26609.1 - 0.029 13.4 7.3 0.038 13.0 5.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4515 PF14988.1 EPE26609.1 - 0.034 13.8 8.6 0.048 13.3 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) AAA_13 PF13166.1 EPE26609.1 - 0.076 11.4 4.4 0.095 11.1 3.1 1.0 1 0 0 1 1 1 0 AAA domain DivIC PF04977.10 EPE26609.1 - 0.21 11.0 10.6 0.18 11.2 5.8 1.9 1 1 1 2 2 2 0 Septum formation initiator DUF2968 PF11180.3 EPE26609.1 - 0.23 10.8 4.7 0.34 10.2 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF869 PF05911.6 EPE26609.1 - 0.26 9.4 10.0 0.36 9.0 6.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF342 PF03961.8 EPE26609.1 - 0.51 8.7 4.3 0.65 8.3 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 EPE26609.1 - 0.59 10.6 8.6 1.8 9.0 4.0 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 EPE26609.1 - 0.6 10.4 5.9 1 9.7 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 EPE26609.1 - 0.69 9.5 6.0 0.94 9.1 4.1 1.1 1 0 0 1 1 1 0 Mnd1 family DUF1635 PF07795.6 EPE26609.1 - 0.77 9.0 8.5 0.63 9.3 4.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) RAP1 PF07218.6 EPE26609.1 - 0.87 7.6 10.5 1.1 7.2 7.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-C4H2 PF10146.4 EPE26609.1 - 0.96 9.4 8.3 1.4 8.9 5.7 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Macoilin PF09726.4 EPE26609.1 - 1.2 7.2 15.2 1.7 6.7 10.6 1.2 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 EPE26609.1 - 1.8 6.3 5.2 2.3 5.9 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 EPE26609.1 - 1.9 7.9 4.2 2.9 7.3 2.9 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 EPE26609.1 - 2.2 8.1 16.5 3.8 7.3 11.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding LPP PF04728.8 EPE26610.1 - 0.022 14.5 0.4 0.062 13.1 0.3 1.8 1 1 0 1 1 1 0 Lipoprotein leucine-zipper GAS PF13851.1 EPE26610.1 - 0.17 11.0 27.7 0.88 8.7 19.1 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3166 PF11365.3 EPE26610.1 - 0.55 10.7 11.1 0.59 10.6 4.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) V_ATPase_I PF01496.14 EPE26610.1 - 3.9 5.2 12.7 4.7 4.9 8.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.10 EPE26610.1 - 6.2 5.9 15.6 8.8 5.4 10.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit U79_P34 PF03064.11 EPE26611.1 - 0.31 10.5 5.7 0.37 10.2 4.0 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Cyclin PF08613.6 EPE26614.1 - 4.3e-13 49.9 0.5 1.4e-12 48.2 0.0 2.2 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EPE26614.1 - 0.031 13.8 0.0 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain Zn_clus PF00172.13 EPE26615.1 - 2.3e-05 24.1 8.5 3.9e-05 23.4 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE26615.1 - 0.0022 16.6 0.0 0.0047 15.5 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.20 EPE26616.1 - 2.3e-57 194.1 0.0 1.5e-56 191.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE26616.1 - 3.2e-27 95.2 0.7 1.7e-19 69.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EPE26616.1 - 5.6e-07 29.9 1.0 1.9e-06 28.2 0.4 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPE26616.1 - 0.0017 17.3 0.1 0.0052 15.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPE26616.1 - 0.0064 16.2 0.0 0.16 11.6 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family HSP9_HSP12 PF04119.7 EPE26617.1 - 5.5e-22 77.6 3.8 1.9e-21 75.9 0.6 2.1 1 1 0 2 2 2 1 Heat shock protein 9/12 DUF4398 PF14346.1 EPE26617.1 - 0.16 12.0 1.4 0.31 11.0 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) YtxH PF12732.2 EPE26617.1 - 0.17 12.2 1.9 1 9.7 0.3 2.0 1 1 1 2 2 2 0 YtxH-like protein adh_short PF00106.20 EPE26618.1 - 7.9e-28 97.4 0.0 1.1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE26618.1 - 1.4e-12 47.6 0.0 2.3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE26618.1 - 7.5e-12 45.5 0.0 9.4e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EPE26618.1 - 0.0038 16.9 0.1 0.012 15.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Thymidylat_synt PF00303.14 EPE26620.1 - 2.7e-107 357.7 0.0 3e-107 357.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase PAP2 PF01569.16 EPE26621.1 - 1.4e-13 50.6 0.0 2.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily TauD PF02668.11 EPE26622.1 - 7.7e-52 176.5 0.2 9.3e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EPE26623.1 - 2.3e-32 112.1 18.4 2.3e-32 112.1 12.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.2 EPE26623.1 - 0.0028 17.5 0.9 0.0028 17.5 0.6 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3792) MFS_1_like PF12832.2 EPE26623.1 - 0.0068 16.1 2.0 0.066 13.0 1.1 2.5 2 0 0 2 2 2 1 MFS_1 like family adh_short PF00106.20 EPE26624.1 - 4.3e-16 59.2 0.0 9.1e-16 58.2 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE26624.1 - 2.2e-06 27.6 0.0 3.2e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE26624.1 - 6.1e-06 26.0 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 KR domain TrfA PF07042.6 EPE26624.1 - 0.047 12.5 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 TrfA protein NAD_binding_10 PF13460.1 EPE26624.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 EPE26625.1 - 1.1e-65 222.0 0.0 2.1e-65 221.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 SET PF00856.23 EPE26626.1 - 5.7e-10 39.7 0.0 7.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 SET domain DUF4537 PF15057.1 EPE26627.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) FlxA PF14282.1 EPE26627.1 - 0.085 12.8 0.3 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 FlxA-like protein Cep57_MT_bd PF06657.8 EPE26627.1 - 0.15 12.0 1.3 0.27 11.2 0.9 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 CCDC-167 PF15188.1 EPE26627.1 - 0.31 10.9 1.5 0.54 10.2 1.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PixA PF12306.3 EPE26627.1 - 0.82 9.4 3.1 0.85 9.4 0.3 2.2 2 1 0 2 2 2 0 Inclusion body protein DUF572 PF04502.8 EPE26628.1 - 6.2e-59 199.8 0.0 7.9e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Adeno_100 PF02438.11 EPE26629.1 - 0.094 10.9 0.1 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Late 100kD protein Gp23 PF07068.6 EPE26630.1 - 0.13 10.7 0.2 0.16 10.4 0.1 1.1 1 0 0 1 1 1 0 Major capsid protein Gp23 Tyrosinase PF00264.15 EPE26631.1 - 3.3e-46 158.2 0.3 4.4e-46 157.8 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Acetyltransf_3 PF13302.1 EPE26632.1 - 2.8e-32 111.8 0.0 3.3e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE26632.1 - 0.0059 16.6 0.1 0.013 15.5 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EPE26632.1 - 0.031 14.1 0.1 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain WD40 PF00400.27 EPE26634.1 - 1.6e-10 40.4 17.9 7.8e-05 22.4 0.3 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.17 EPE26634.1 - 0.00013 21.8 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain Integrin_b_cyt PF08725.6 EPE26634.1 - 0.016 14.5 0.2 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain UQ_con PF00179.21 EPE26635.1 - 3.7e-38 130.0 0.1 7.4e-38 129.1 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPE26635.1 - 0.067 13.0 0.1 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 EPE26635.1 - 0.1 12.3 0.1 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic E2 family B TRI12 PF06609.8 EPE26636.1 - 4.9e-38 130.7 26.7 6.1e-38 130.4 18.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EPE26636.1 - 6.8e-19 67.7 48.6 6.8e-19 67.7 33.7 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26636.1 - 3.6e-07 29.1 13.0 3.6e-07 29.1 9.0 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Phage_holin_1 PF04531.8 EPE26636.1 - 0.21 11.6 1.6 1.4 9.0 0.0 3.0 2 1 0 2 2 2 0 Bacteriophage holin zf-C2H2 PF00096.21 EPE26637.1 - 4.6e-05 23.5 52.8 0.0018 18.4 0.3 8.6 8 1 1 9 9 9 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE26637.1 - 7.9e-05 22.7 38.0 0.019 15.2 3.3 7.2 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EPE26637.1 - 0.22 11.6 17.5 3 7.9 0.6 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-MYND PF01753.13 EPE26638.1 - 1.3e-10 40.9 12.8 2e-10 40.3 8.9 1.3 1 0 0 1 1 1 1 MYND finger DUF4157 PF13699.1 EPE26638.1 - 0.099 12.7 0.2 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) Clathrin PF00637.15 EPE26639.1 - 0.41 10.2 0.0 0.71 9.4 0.0 1.3 1 0 0 1 1 1 0 Region in Clathrin and VPS tRNA_U5-meth_tr PF05958.6 EPE26644.1 - 1.7e-12 46.7 0.0 1.2e-10 40.6 0.0 2.9 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.15 EPE26644.1 - 2.5e-06 27.1 2.1 2.8e-06 27.0 0.1 2.0 2 0 0 2 2 2 1 TRAM domain Methyltransf_31 PF13847.1 EPE26644.1 - 1.5e-05 24.6 0.0 2.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EPE26644.1 - 2.2e-05 24.0 0.0 5.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EPE26644.1 - 0.0028 18.2 0.0 0.0075 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPE26644.1 - 0.0032 16.6 0.0 0.006 15.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) SIR2 PF02146.12 EPE26646.1 - 3.3e-26 92.0 0.0 2.6e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 EPE26646.1 - 0.024 14.4 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF4231 PF14015.1 EPE26646.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) GTP_EFTU PF00009.22 EPE26647.1 - 5.1e-44 149.9 0.0 8.6e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPE26647.1 - 3.9e-22 78.2 0.1 1.1e-21 76.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPE26647.1 - 1.8e-05 24.7 0.1 4.8e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPE26647.1 - 0.00011 22.0 0.0 0.00031 20.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EPE26647.1 - 0.14 10.7 0.4 0.23 10.1 0.2 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Ran-binding PF05508.6 EPE26648.1 - 3.2e-100 334.9 0.1 4e-100 334.6 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein DUF2726 PF10881.3 EPE26648.1 - 0.017 14.7 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) MFS_1 PF07690.11 EPE26649.1 - 1.7e-15 56.6 3.4 1.7e-15 56.6 2.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EPE26649.1 - 2.5e-07 30.2 3.3 2.5e-07 30.2 2.3 2.0 2 0 0 2 2 2 1 Nodulin-like DUF4516 PF14990.1 EPE26649.1 - 0.12 11.8 1.1 0.44 10.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) RecX PF02631.11 EPE26649.1 - 0.23 11.6 2.6 0.78 9.9 1.9 1.7 1 1 0 1 1 1 0 RecX family WSC PF01822.14 EPE26650.1 - 6e-72 237.6 71.7 5.4e-21 74.3 9.0 4.6 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 EPE26650.1 - 8e-30 103.6 0.0 4.8e-28 97.8 0.0 2.9 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EPE26650.1 - 6.8e-23 80.6 0.0 1.5e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Mitoc_L55 PF09776.4 EPE26650.1 - 0.13 11.9 0.0 0.81 9.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 DNA_binding_1 PF01035.15 EPE26652.1 - 2.7e-05 23.8 0.0 5.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain AAA_27 PF13514.1 EPE26652.1 - 0.81 7.2 3.2 0.2 9.3 0.1 1.4 2 0 0 2 2 2 0 AAA domain Fungal_trans_2 PF11951.3 EPE26653.1 - 7.5e-05 21.4 0.0 0.0013 17.4 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE26653.1 - 0.00038 20.2 2.5 0.00038 20.2 1.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_lectin PF07938.7 EPE26654.1 - 2.3e-07 30.4 0.0 0.011 15.0 0.0 2.3 1 1 0 2 2 2 2 Fungal fucose-specific lectin WD40 PF00400.27 EPE26654.1 - 0.00092 19.0 0.1 18 5.3 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat PD40 PF07676.7 EPE26654.1 - 0.031 13.9 0.0 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat bZIP_1 PF00170.16 EPE26654.1 - 0.13 12.2 3.7 0.27 11.2 2.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor zf-RING_4 PF14570.1 EPE26655.1 - 4.6e-19 67.7 12.0 7.5e-19 67.0 8.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EPE26655.1 - 8.2e-07 28.5 0.0 1.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE26655.1 - 6.1e-06 25.9 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EPE26655.1 - 2.6e-05 23.8 7.3 4.2e-05 23.1 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE26655.1 - 0.0013 18.5 9.3 0.0022 17.7 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 EPE26655.1 - 0.0025 17.0 4.9 0.0025 17.0 3.4 3.7 3 1 0 3 3 2 1 Rtf2 RING-finger RRM_6 PF14259.1 EPE26655.1 - 0.0066 16.4 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FYVE_2 PF02318.11 EPE26655.1 - 0.008 16.0 4.7 0.008 16.0 3.2 2.5 2 1 1 3 3 3 1 FYVE-type zinc finger Baculo_IE-1 PF05290.6 EPE26655.1 - 0.045 13.4 5.8 0.093 12.4 4.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) SET_assoc PF11767.3 EPE26655.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-RING_5 PF14634.1 EPE26655.1 - 0.15 11.8 10.6 0.25 11.0 7.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain FYVE PF01363.16 EPE26655.1 - 0.2 11.5 4.1 0.47 10.3 2.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-UDP PF14569.1 EPE26655.1 - 0.42 10.4 3.8 1 9.1 2.7 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 EPE26655.1 - 0.59 10.1 10.9 1 9.4 7.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE26655.1 - 2.5 7.8 11.0 4.6 6.9 7.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EPE26655.1 - 2.8 7.5 9.2 0.63 9.6 2.9 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Complex1_30kDa PF00329.14 EPE26656.1 - 1e-35 122.0 0.0 1.7e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Patched PF02460.13 EPE26657.1 - 3.8e-79 266.5 2.5 6.2e-79 265.8 1.7 1.3 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EPE26657.1 - 7.7e-53 178.0 6.2 7.7e-53 178.0 4.3 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EPE26657.1 - 1e-05 24.4 8.4 1e-05 24.4 5.8 2.5 2 0 0 2 2 2 2 MMPL family HECT PF00632.20 EPE26658.1 - 3.7e-81 272.7 0.0 7.7e-81 271.6 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 EPE26658.1 - 0.024 14.4 2.9 22 5.0 0.1 5.8 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EPE26658.1 - 0.24 11.5 1.6 12 6.3 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat RRN3 PF05327.6 EPE26658.1 - 0.39 8.7 10.0 0.069 11.2 2.9 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Clr5 PF14420.1 EPE26658.1 - 0.6 10.0 1.9 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 Clr5 domain E1_dh PF00676.15 EPE26659.1 - 1.1e-87 293.5 0.0 1.8e-87 292.8 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Smr PF01713.16 EPE26659.1 - 8.9e-12 45.0 0.7 2.4e-11 43.6 0.5 1.8 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EPE26659.1 - 5.9e-05 22.9 11.6 0.00012 21.9 8.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.11 EPE26659.1 - 0.00019 20.8 0.0 0.0018 17.7 0.0 2.8 3 0 0 3 3 3 1 CUE domain TPP_enzyme_C PF02775.16 EPE26659.1 - 0.0016 17.9 0.0 0.011 15.3 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EPE26659.1 - 0.046 12.6 0.0 0.1 11.4 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase adh_short PF00106.20 EPE26663.1 - 3.1e-13 49.9 0.0 6.3e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EPE26663.1 - 7.9e-07 28.9 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE26663.1 - 1.7e-05 24.7 0.0 3.2e-05 23.8 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EPE26663.1 - 0.035 12.8 0.0 0.047 12.3 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BTB PF00651.26 EPE26664.1 - 2.2e-06 27.6 0.0 3.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PTCB-BRCT PF12738.2 EPE26665.1 - 4.1e-11 42.5 0.0 7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EPE26665.1 - 9.2e-10 38.5 0.0 1.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EPE26665.1 - 0.0005 20.1 0.1 0.0028 17.7 0.1 2.2 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 EPE26665.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) eIF-1a PF01176.14 EPE26667.1 - 4.2e-28 96.5 0.0 6.1e-28 96.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.18 EPE26668.1 - 1.2e-28 99.0 0.2 1.6e-28 98.6 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EPE26668.1 - 0.0006 19.3 0.2 0.0014 18.1 0.1 1.7 1 0 0 1 1 1 1 WH2 motif ERCC4 PF02732.10 EPE26670.1 - 4.7e-26 91.2 0.0 1.3e-25 89.7 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain Glycoprotein_B PF00606.13 EPE26671.1 - 0.0047 15.0 1.0 0.0047 15.0 0.7 1.0 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B CorA PF01544.13 EPE26674.1 - 6e-09 35.3 0.1 1.1e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Aldedh PF00171.17 EPE26675.1 - 2.2e-120 402.1 0.0 2.6e-120 401.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1644 PF07800.7 EPE26676.1 - 0.016 15.0 2.3 0.035 13.9 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) HhH-GPD PF00730.20 EPE26678.1 - 6.7e-10 39.2 0.0 1.4e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein VirionAssem_T7 PF11653.3 EPE26678.1 - 0.78 10.5 5.0 0.69 10.7 0.6 2.6 1 1 1 2 2 2 0 Bacteriophage T7 virion assembly protein GATase_2 PF00310.16 EPE26679.1 - 4.2e-21 75.0 0.0 5.8e-16 58.1 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EPE26679.1 - 1.1e-16 61.0 0.0 2.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EPE26679.1 - 1.2e-14 54.0 0.0 2.3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EPE26679.1 - 2.7e-11 43.2 0.0 8e-11 41.7 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EPE26679.1 - 0.00027 19.6 0.0 0.00046 18.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.21 EPE26679.1 - 0.0083 15.6 0.1 0.18 11.3 0.0 2.9 4 0 0 4 4 4 1 Zinc-binding dehydrogenase DNA_methylase PF00145.12 EPE26680.1 - 7.8e-34 117.2 0.0 7.2e-22 77.9 0.0 2.3 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase SPT6_acidic PF14632.1 EPE26680.1 - 0.23 11.6 9.2 0.2 11.8 4.9 2.1 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Ribosomal_L14e PF01929.12 EPE26681.1 - 2.7e-28 98.1 5.4 3.9e-28 97.5 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EPE26681.1 - 1.5e-05 24.5 0.2 3e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 KOW motif AAA_11 PF13086.1 EPE26681.1 - 0.0059 16.2 0.1 0.0071 15.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE26681.1 - 0.038 13.7 0.2 0.079 12.7 0.1 1.8 1 1 0 1 1 1 0 Part of AAA domain Tfb2 PF03849.9 EPE26681.1 - 0.052 12.1 0.4 0.063 11.9 0.3 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 NAC PF01849.13 EPE26682.1 - 6.2e-24 83.3 0.1 5.7e-23 80.2 0.0 2.1 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EPE26682.1 - 0.0063 16.3 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain SelP_N PF04592.9 EPE26682.1 - 1.2 8.4 5.9 2.1 7.6 4.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2946 PF11162.3 EPE26682.1 - 4.6 7.4 5.6 9.1 6.5 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Mt_ATP-synt_D PF05873.7 EPE26683.1 - 3.2e-18 65.8 0.6 3.9e-18 65.6 0.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Syntaxin PF00804.20 EPE26683.1 - 0.016 15.3 2.1 0.026 14.6 1.3 1.5 1 1 0 1 1 1 0 Syntaxin Staph_haemo PF05480.6 EPE26683.1 - 0.061 13.0 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Staphylococcus haemolytic protein DUF2799 PF10973.3 EPE26683.1 - 0.079 12.9 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2799) BLOC1_2 PF10046.4 EPE26683.1 - 0.19 11.9 1.9 0.97 9.6 0.5 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Abhydrolase_3 PF07859.8 EPE26684.1 - 3.9e-33 114.8 0.0 5.2e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE26684.1 - 7.8e-06 25.7 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE26684.1 - 0.02 14.8 0.1 0.031 14.1 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family SRP-alpha_N PF04086.8 EPE26686.1 - 1.1e-82 277.6 0.0 1.4e-82 277.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EPE26686.1 - 3.9e-40 137.4 0.1 8e-40 136.3 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Isochorismatase PF00857.15 EPE26686.1 - 2.4e-25 89.4 0.0 8e-25 87.7 0.0 1.9 2 0 0 2 2 2 1 Isochorismatase family ArgK PF03308.11 EPE26686.1 - 2.3e-07 29.8 0.0 4.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein SRP54_N PF02881.14 EPE26686.1 - 4.9e-06 26.5 0.1 1.8e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 EPE26686.1 - 6.1e-05 22.5 0.1 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EPE26686.1 - 0.0012 18.8 0.0 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 EPE26686.1 - 0.0025 17.5 0.1 0.0065 16.1 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_NifH PF00142.13 EPE26686.1 - 0.017 14.2 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Neuropep_like PF15161.1 EPE26686.1 - 0.024 14.0 0.2 0.053 12.9 0.1 1.5 1 0 0 1 1 1 0 Neuropeptide-like MMR_HSR1 PF01926.18 EPE26686.1 - 0.025 14.5 0.1 0.47 10.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 EPE26686.1 - 0.13 11.9 0.1 0.6 9.7 0.0 2.1 2 0 0 2 2 2 0 NTPase YIF1 PF03878.10 EPE26687.1 - 3.6e-76 255.4 1.2 4.2e-76 255.2 0.8 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EPE26687.1 - 0.00014 21.3 5.8 0.00027 20.4 4.0 1.4 1 0 0 1 1 1 1 Yip1 domain DUF4014 PF13198.1 EPE26687.1 - 0.12 12.7 1.1 0.28 11.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) DUF619 PF04768.8 EPE26689.1 - 6.7e-51 172.0 0.5 1.6e-50 170.8 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EPE26689.1 - 5.4e-30 104.1 0.0 1.9e-29 102.4 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EPE26689.1 - 1.4e-25 90.2 0.0 2.6e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family GFO_IDH_MocA PF01408.17 EPE26689.1 - 0.023 15.1 0.0 0.076 13.5 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EPE26689.1 - 0.04 13.8 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.16 EPE26690.1 - 3.6e-34 116.2 0.9 4.1e-34 116.0 0.6 1.0 1 0 0 1 1 1 1 Synaptobrevin Glyco_hydro_76 PF03663.9 EPE26691.1 - 8.9e-159 528.7 24.2 1.1e-158 528.4 16.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EPE26691.1 - 0.086 11.8 8.6 0.1 11.6 0.3 3.0 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 PrpF PF04303.8 EPE26692.1 - 1.2e-101 340.1 2.7 4.8e-101 338.1 1.9 1.7 1 1 0 1 1 1 1 PrpF protein Transaldolase PF00923.14 EPE26693.1 - 6.3e-46 156.7 0.6 7.8e-46 156.4 0.4 1.1 1 0 0 1 1 1 1 Transaldolase Ferritin_2 PF13668.1 EPE26694.1 - 3e-45 153.5 2.2 4e-45 153.1 1.6 1.2 1 0 0 1 1 1 1 Ferritin-like domain DinB_2 PF12867.2 EPE26695.1 - 0.13 12.6 4.3 1.1 9.6 1.3 2.2 1 1 1 2 2 2 0 DinB superfamily MFS_1 PF07690.11 EPE26696.1 - 2.8e-34 118.3 17.7 2.8e-34 118.3 12.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26696.1 - 1.7e-11 43.4 12.4 6.2e-10 38.2 3.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EPE26696.1 - 4.7e-07 28.5 15.7 3.4e-06 25.7 1.3 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EPE26696.1 - 0.011 15.4 0.3 0.12 12.2 0.0 2.8 2 0 0 2 2 2 0 MFS_1 like family MFS_3 PF05977.8 EPE26696.1 - 0.024 12.7 3.3 0.58 8.2 0.9 2.3 1 1 1 2 2 2 0 Transmembrane secretion effector TRI12 PF06609.8 EPE26696.1 - 0.038 12.1 1.4 0.058 11.5 1.0 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.13 EPE26696.1 - 0.071 11.6 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF4040 PF13244.1 EPE26696.1 - 2.1 8.3 6.8 5.2 7.1 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4040) Glyco_hydro_92 PF07971.7 EPE26699.1 - 1.1e-165 552.1 0.0 1.4e-165 551.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Barwin PF00967.12 EPE26701.1 - 0.13 11.9 0.7 0.14 11.8 0.5 1.1 1 0 0 1 1 1 0 Barwin family Glyco_hydro_3 PF00933.16 EPE26702.1 - 8.2e-89 297.5 0.0 1.2e-88 297.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE26702.1 - 6.3e-54 182.8 0.3 1.9e-52 178.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE26702.1 - 8.4e-23 80.1 0.7 1.6e-22 79.2 0.5 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.19 EPE26704.1 - 6.8e-74 249.0 29.3 8.1e-74 248.8 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE26704.1 - 4.6e-18 65.0 29.7 4.6e-18 65.0 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE26704.1 - 9 4.5 34.3 0.12 10.7 3.0 3.2 3 1 0 4 4 4 0 MFS/sugar transport protein MFS_1 PF07690.11 EPE26705.1 - 2e-31 108.9 38.5 2e-31 108.9 26.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26705.1 - 3.9e-10 38.8 25.8 6.2e-10 38.2 17.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Adeno_E3_CR2 PF02439.10 EPE26706.1 - 0.046 13.2 1.4 0.088 12.3 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DAG1 PF05454.6 EPE26706.1 - 0.27 10.4 0.0 0.27 10.4 0.0 3.0 3 0 0 3 3 3 0 Dystroglycan (Dystrophin-associated glycoprotein 1) CN_hydrolase PF00795.17 EPE26708.1 - 5.5e-30 104.1 0.0 8e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_76 PF03663.9 EPE26709.1 - 3.4e-151 503.8 8.8 4.5e-151 503.4 6.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_16 PF00722.16 EPE26710.1 - 2.7e-18 65.8 0.8 7.1e-18 64.5 0.4 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Arabinose_trans PF04602.7 EPE26710.1 - 0.01 14.0 0.0 0.017 13.2 0.0 1.2 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein Glyco_trans_2_3 PF13632.1 EPE26711.1 - 9.9e-49 165.6 2.2 2.4e-48 164.4 1.5 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPE26711.1 - 8.6e-06 25.7 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EPE26711.1 - 0.00019 21.1 0.0 0.00078 19.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EPE26711.1 - 0.00091 18.5 0.0 0.0019 17.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Fasciclin PF02469.17 EPE26712.1 - 8.3e-40 135.7 2.1 2e-21 76.3 0.5 2.2 2 0 0 2 2 2 2 Fasciclin domain Ferritin_2 PF13668.1 EPE26713.1 - 4.5e-44 149.7 2.0 6.8e-44 149.1 1.4 1.3 1 0 0 1 1 1 1 Ferritin-like domain PsbI PF02532.9 EPE26713.1 - 0.14 11.7 0.5 0.29 10.7 0.3 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Gln-synt_C PF00120.19 EPE26714.1 - 7.1e-64 215.4 0.0 9.7e-64 214.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 EPE26715.1 - 3.6e-27 95.3 1.6 5.1e-27 94.8 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE26715.1 - 3e-18 66.4 0.0 3.9e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE26715.1 - 6.3e-10 39.0 1.2 1e-09 38.2 0.8 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EPE26715.1 - 0.00029 20.5 0.1 0.00044 19.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EPE26715.1 - 0.0016 17.9 0.1 0.0022 17.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPE26715.1 - 0.0021 17.0 0.1 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_18 PF12847.2 EPE26715.1 - 0.038 14.5 0.0 0.29 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 EPE26715.1 - 0.056 13.2 2.0 0.25 11.1 0.4 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_12 PF08242.7 EPE26715.1 - 0.063 13.7 0.0 0.13 12.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EPE26715.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain THF_DHG_CYH_C PF02882.14 EPE26715.1 - 0.075 12.1 0.1 0.18 10.9 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.14 EPE26715.1 - 0.11 11.1 0.1 0.5 9.0 0.1 1.9 1 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPE26715.1 - 0.14 12.1 0.9 0.44 10.5 0.5 1.9 2 1 0 2 2 2 0 NADH(P)-binding AMP-binding PF00501.23 EPE26716.1 - 8.5e-73 245.1 0.0 1.1e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE26716.1 - 1e-07 32.7 0.0 2.4e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PHY PF00360.15 EPE26717.1 - 1.9e-25 89.0 0.0 4.6e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 EPE26717.1 - 1.3e-18 66.7 0.1 2.8e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE26717.1 - 1.1e-15 57.5 0.0 3.1e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 EPE26717.1 - 4.4e-15 56.1 0.0 1.2e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.20 EPE26717.1 - 2.6e-13 49.7 0.5 8.7e-13 48.0 0.4 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EPE26717.1 - 9e-10 38.9 0.0 2.5e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.1 EPE26717.1 - 0.01 15.4 0.3 0.022 14.4 0.2 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Copper-fist PF00649.13 EPE26718.1 - 1.8e-21 75.0 1.8 1.8e-21 75.0 1.2 3.0 2 1 1 3 3 3 1 Copper fist DNA binding domain MaoC_dehydratas PF01575.14 EPE26718.1 - 0.13 11.5 0.2 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 MaoC like domain GTP_EFTU PF00009.22 EPE26719.1 - 7.4e-39 133.1 3.5 7.4e-39 133.1 2.4 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EPE26719.1 - 1.2e-24 86.2 0.9 3.1e-24 84.9 0.6 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EPE26719.1 - 3.5e-10 39.8 0.4 0.00017 21.6 0.0 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPE26719.1 - 1.3e-07 31.5 0.1 3e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.10 EPE26719.1 - 1.6e-07 30.8 0.0 3.5e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 EPE26719.1 - 3.1e-06 27.6 0.1 8e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE26719.1 - 1.9e-05 23.9 0.0 3.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 EPE26719.1 - 0.00024 20.6 0.5 0.00062 19.2 0.3 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EPE26719.1 - 0.00065 18.9 0.1 0.0018 17.5 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EPE26719.1 - 0.00097 18.4 0.2 0.0031 16.8 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU_D4 PF14578.1 EPE26719.1 - 0.0076 15.8 2.2 0.044 13.4 0.8 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Hydrolase_6 PF13344.1 EPE26719.1 - 0.027 14.3 0.0 2.5 8.0 0.0 2.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Dynamin_N PF00350.18 EPE26719.1 - 1.2 8.9 9.8 6 6.6 0.0 3.9 3 1 1 4 4 4 0 Dynamin family 2-Hacid_dh_C PF02826.14 EPE26720.1 - 5.3e-39 133.2 0.0 8.4e-39 132.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPE26720.1 - 2.2e-24 85.4 0.1 3e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPE26720.1 - 0.0012 18.7 0.1 0.0036 17.1 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EPE26720.1 - 0.017 14.9 0.0 0.094 12.5 0.0 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 EPE26720.1 - 0.028 14.8 1.1 0.061 13.7 0.1 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EPE26720.1 - 0.039 14.2 0.1 0.26 11.5 0.0 2.3 3 1 0 3 3 3 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EPE26720.1 - 0.043 13.4 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 EPE26720.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain adh_short PF00106.20 EPE26720.1 - 0.33 10.8 2.2 0.23 11.3 0.2 1.7 2 0 0 2 2 2 0 short chain dehydrogenase DUF2205 PF10224.4 EPE26721.1 - 0.016 14.7 0.4 0.057 12.9 0.3 1.9 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Reo_sigmaC PF04582.7 EPE26721.1 - 0.072 12.2 0.2 2.6 7.1 0.2 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein FliD_N PF02465.13 EPE26721.1 - 0.085 13.2 0.7 12 6.3 0.0 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Scaffolding_pro PF11418.3 EPE26721.1 - 0.12 12.6 7.6 1.4 9.2 0.0 3.4 3 1 0 3 3 3 0 Phi29 scaffolding protein Lge1 PF11488.3 EPE26721.1 - 0.28 11.4 5.3 0.48 10.6 0.4 3.1 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 DUF677 PF05055.7 EPE26723.1 - 0.086 11.5 1.0 0.4 9.2 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF677) Dynamin_N PF00350.18 EPE26724.1 - 2.2e-25 89.4 1.3 4.5e-25 88.4 0.0 2.2 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EPE26724.1 - 1.6e-11 43.5 0.2 3.1e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EPE26724.1 - 0.00011 22.0 0.0 0.00043 20.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 EPE26724.1 - 0.021 14.6 0.3 0.16 11.8 0.1 2.5 2 0 0 2 2 2 0 Dynamin GTPase effector domain DUF676 PF05057.9 EPE26725.1 - 0.015 14.6 0.1 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_16 PF13191.1 EPE26725.1 - 0.022 14.7 0.1 0.21 11.5 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain PGAP1 PF07819.8 EPE26725.1 - 0.027 14.0 0.3 0.068 12.7 0.1 1.7 2 0 0 2 2 2 0 PGAP1-like protein AAA_22 PF13401.1 EPE26725.1 - 0.1 12.7 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain FHA PF00498.21 EPE26726.1 - 9e-14 51.3 0.0 1.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF2431 PF10354.4 EPE26727.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) DUF2076 PF09849.4 EPE26727.1 - 0.17 11.9 1.2 0.36 10.8 0.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pkinase PF00069.20 EPE26730.1 - 1.4e-21 76.8 0.0 2.3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE26730.1 - 2.1e-11 43.4 0.0 1e-10 41.1 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Glyco_transf_25 PF01755.12 EPE26731.1 - 0.0084 15.7 0.2 0.089 12.4 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) nlz1 PF12402.3 EPE26732.1 - 0.16 12.3 31.5 6.5 7.1 0.2 6.1 5 1 1 6 6 6 0 NocA-like zinc-finger protein 1 Herpes_US9 PF06072.6 EPE26733.1 - 0.075 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 MFS_1 PF07690.11 EPE26735.1 - 8.1e-37 126.7 44.0 9.6e-37 126.5 29.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Carn_acyltransf PF00755.15 EPE26736.1 - 7.6e-83 278.5 0.0 1.1e-81 274.7 0.0 2.1 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.21 EPE26736.1 - 7.9e-77 258.1 0.0 1.6e-76 257.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPE26736.1 - 1.9e-45 155.6 0.2 2.9e-45 154.9 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EPE26736.1 - 1e-42 146.3 0.0 1.7e-41 142.3 0.0 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EPE26736.1 - 1.7e-36 124.6 0.2 5.9e-36 122.9 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EPE26736.1 - 1.4e-13 50.5 0.0 4.8e-13 48.7 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE26736.1 - 2.7e-11 44.4 0.0 1.9e-10 41.7 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KR PF08659.5 EPE26736.1 - 9.7e-10 38.3 0.0 1.4e-08 34.6 0.0 2.7 2 0 0 2 2 2 1 KR domain PP-binding PF00550.20 EPE26736.1 - 1.4e-07 31.6 0.1 8.4e-06 25.9 0.1 3.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 EPE26736.1 - 2.4e-07 30.8 0.2 2.2e-06 27.7 0.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.7 EPE26736.1 - 0.00015 22.1 0.2 0.00099 19.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 EPE26736.1 - 0.027 14.2 0.1 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EPE26736.1 - 0.088 13.3 0.1 0.55 10.7 0.0 2.5 2 0 0 2 2 1 0 Methyltransferase domain Glyco_hydro_43 PF04616.9 EPE26738.1 - 4.7e-15 55.4 0.9 8.4e-15 54.6 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AT_hook PF02178.14 EPE26740.1 - 0.082 12.6 0.2 0.082 12.6 0.2 3.1 3 0 0 3 3 3 0 AT hook motif Bac_rhamnosid PF05592.6 EPE26741.1 - 8.8e-36 123.1 1.1 4.6e-30 104.3 0.3 2.5 2 2 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EPE26741.1 - 0.00037 19.3 2.2 0.0011 17.7 1.8 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF608 WD40 PF00400.27 EPE26742.1 - 3.3e-08 33.1 2.1 0.001 18.8 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Nop14 PF04147.7 EPE26742.1 - 0.061 11.2 10.2 0.088 10.7 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family YqfQ PF14181.1 EPE26742.1 - 0.14 12.1 3.3 0.24 11.4 2.3 1.3 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.9 EPE26742.1 - 1.3 6.9 16.4 1.8 6.5 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 EPE26742.1 - 1.3 7.9 15.2 1.9 7.4 10.6 1.1 1 0 0 1 1 1 0 BUD22 NAM-associated PF14303.1 EPE26742.1 - 1.6 9.0 9.7 2.7 8.2 6.7 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain TFIIF_alpha PF05793.7 EPE26742.1 - 1.9 6.7 17.7 2.9 6.1 12.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TATR PF03430.8 EPE26742.1 - 2.8 6.4 5.3 3.8 6.0 3.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF3176 PF11374.3 EPE26743.1 - 4.9e-29 100.4 1.5 6.9e-29 99.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) ESSS PF10183.4 EPE26743.1 - 0.033 14.5 0.1 0.092 13.1 0.1 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Amidase PF01425.16 EPE26745.1 - 3e-99 332.8 0.0 3.6e-99 332.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Oxidored_FMN PF00724.15 EPE26747.1 - 8.6e-48 163.0 0.0 2.8e-47 161.3 0.0 1.6 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Metallophos PF00149.23 EPE26749.1 - 5.8e-39 133.5 0.1 7.8e-39 133.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SNARE PF05739.14 EPE26750.1 - 3.9e-10 39.2 4.7 8.9e-10 38.1 3.3 1.6 1 0 0 1 1 1 1 SNARE domain MCPsignal PF00015.16 EPE26750.1 - 0.0072 15.8 4.4 0.0072 15.8 3.0 1.9 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 EPE26750.1 - 0.019 14.5 3.9 0.051 13.1 2.7 1.8 1 0 0 1 1 1 0 Synaptobrevin Rifin_STEVOR PF02009.11 EPE26750.1 - 0.057 13.0 4.4 0.13 11.8 3.0 1.7 1 1 0 1 1 1 0 Rifin/stevor family Cytochrom_C_2 PF01322.15 EPE26750.1 - 0.28 11.7 3.6 5 7.6 0.3 2.5 2 0 0 2 2 2 0 Cytochrome C' DUF2951 PF11166.3 EPE26750.1 - 0.85 9.5 6.6 0.12 12.2 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) SlyX PF04102.7 EPE26750.1 - 1.3 9.4 4.2 9.9 6.6 0.3 3.0 2 1 0 2 2 2 0 SlyX Ank_2 PF12796.2 EPE26751.1 - 1.7e-77 255.7 12.9 2.9e-16 59.5 0.0 6.6 3 2 1 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EPE26751.1 - 5.1e-58 190.1 32.3 1.9e-06 27.3 0.2 15.2 16 0 0 16 16 16 12 Ankyrin repeat Ank_4 PF13637.1 EPE26751.1 - 3.6e-49 164.2 12.7 1.9e-06 28.2 0.0 11.4 6 3 4 12 12 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE26751.1 - 1.1e-45 149.0 14.2 0.011 15.8 0.0 14.6 14 0 0 14 14 14 10 Ankyrin repeat Ank_5 PF13857.1 EPE26751.1 - 4.9e-35 118.7 14.0 5.5e-07 29.6 0.1 11.9 6 3 6 12 12 12 9 Ankyrin repeats (many copies) AAA_16 PF13191.1 EPE26751.1 - 4.2e-07 30.1 0.0 1.1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PGAP1 PF07819.8 EPE26751.1 - 4.1e-05 23.2 0.0 8.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.7 EPE26751.1 - 4.3e-05 23.2 0.0 8.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EPE26751.1 - 0.00031 20.8 0.1 0.0017 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF676 PF05057.9 EPE26751.1 - 0.00073 18.8 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPE26751.1 - 0.0063 16.4 0.0 0.026 14.3 0.0 2.1 3 0 0 3 3 2 1 Alpha/beta hydrolase family AAA_19 PF13245.1 EPE26751.1 - 0.022 14.5 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain PG_binding_3 PF09374.5 EPE26751.1 - 0.027 14.4 0.2 0.12 12.3 0.2 2.1 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Shigella_OspC PF06128.6 EPE26751.1 - 0.04 13.4 0.7 10 5.5 0.0 4.1 5 0 0 5 5 5 0 Shigella flexneri OspC protein AAA PF00004.24 EPE26751.1 - 0.041 14.0 0.0 0.37 11.0 0.0 2.6 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF900 PF05990.7 EPE26751.1 - 0.079 12.2 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) RNA_helicase PF00910.17 EPE26751.1 - 0.096 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.15 EPE26751.1 - 0.12 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CorA PF01544.13 EPE26752.1 - 4.4e-11 42.3 1.1 4.4e-11 42.3 0.8 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein COG2 PF06148.6 EPE26752.1 - 0.052 13.4 0.1 4.6 7.1 0.0 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AMP-binding PF00501.23 EPE26753.1 - 3e-87 292.7 0.0 4.7e-87 292.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EPE26753.1 - 5.2e-78 262.0 0.0 1e-77 261.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EPE26753.1 - 5.6e-57 192.3 1.0 5.6e-57 192.3 0.7 2.5 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 EPE26753.1 - 1.8e-53 181.9 0.0 3.2e-53 181.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EPE26753.1 - 3.1e-48 163.8 0.6 3.1e-48 163.8 0.4 3.2 4 0 0 4 4 4 1 short chain dehydrogenase PS-DH PF14765.1 EPE26753.1 - 2e-47 161.8 0.0 5.1e-47 160.4 0.0 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EPE26753.1 - 3.3e-47 160.8 0.0 5.3e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 EPE26753.1 - 1.9e-36 124.4 0.2 2.4e-35 120.9 0.0 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EPE26753.1 - 8e-31 106.8 0.0 2.2e-30 105.4 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein ADH_zinc_N PF00107.21 EPE26753.1 - 4.5e-22 77.9 0.0 1.7e-21 76.1 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EPE26753.1 - 4.7e-18 65.2 0.0 5e-09 36.3 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 EPE26753.1 - 1.8e-13 51.4 0.0 1.7e-10 41.8 0.0 3.7 3 0 0 3 3 3 1 Zinc-binding dehydrogenase HxxPF_rpt PF13745.1 EPE26753.1 - 4e-13 49.5 0.0 9.7e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 HxxPF-repeated domain ADH_N PF08240.7 EPE26753.1 - 0.00095 18.9 0.0 0.0026 17.4 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EPE26753.1 - 0.0039 16.2 0.0 0.01 14.8 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 EPE26753.1 - 0.15 10.6 0.0 3.3 6.3 0.0 2.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family MBOAT_2 PF13813.1 EPE26754.1 - 1.5e-15 57.0 1.6 1.5e-15 57.0 1.1 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MFS_1 PF07690.11 EPE26755.1 - 1e-45 156.0 81.1 3.7e-41 141.0 39.5 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPE26755.1 - 2.2e-18 65.8 26.3 2.9e-18 65.3 18.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE26755.1 - 6.2e-09 34.9 19.4 6.2e-09 34.9 13.5 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 EPE26755.1 - 0.00016 19.9 3.9 0.00016 19.9 2.7 2.6 2 1 0 2 2 2 1 Transmembrane secretion effector LPAM_1 PF08139.7 EPE26755.1 - 0.034 14.3 0.6 0.18 12.0 0.4 2.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Zn_clus PF00172.13 EPE26757.1 - 9.4e-06 25.4 10.4 1.7e-05 24.6 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioesterase PF00975.15 EPE26758.1 - 1.4e-23 84.3 0.0 3.7e-22 79.6 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EPE26758.1 - 5.9e-10 39.4 0.2 1.2e-09 38.3 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE26758.1 - 1.2e-06 28.3 0.0 1.4e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE26758.1 - 4.3e-06 26.4 0.0 4e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 EPE26758.1 - 0.00093 18.6 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 EPE26758.1 - 0.12 11.5 0.2 0.87 8.7 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Asp PF00026.18 EPE26759.1 - 1.9e-16 60.1 0.1 5.1e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.1 EPE26759.1 - 2.8e-05 23.7 0.0 5.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EPE26759.1 - 0.012 15.6 0.5 0.028 14.3 0.2 1.7 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal FAD_binding_3 PF01494.14 EPE26760.1 - 5.8e-27 94.6 0.0 9.7e-27 93.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EPE26760.1 - 0.00011 22.2 0.1 0.00024 21.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE26760.1 - 0.0002 20.4 0.7 0.0014 17.6 0.5 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EPE26760.1 - 0.0013 17.4 0.6 0.92 8.0 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 EPE26760.1 - 0.0019 17.1 0.1 0.003 16.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EPE26760.1 - 0.0037 17.2 0.1 0.0088 16.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE26760.1 - 0.0068 16.2 0.3 0.044 13.6 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE26760.1 - 0.051 13.9 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE26760.1 - 0.11 11.3 1.1 7.7 5.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EPE26760.1 - 0.13 10.6 0.0 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.20 EPE26761.1 - 9.4e-22 77.6 0.8 1.3e-21 77.1 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE26761.1 - 2.4e-17 63.5 0.2 5.2e-17 62.4 0.2 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPE26761.1 - 1.8e-05 24.8 0.1 3.5e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EPE26761.1 - 2.4e-05 24.0 0.1 4e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE26761.1 - 3.2e-05 23.5 0.1 5e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPE26761.1 - 0.0035 16.6 0.3 0.0085 15.3 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family MtaB PF12176.3 EPE26761.1 - 0.07 11.5 0.0 0.099 11.0 0.0 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Eno-Rase_NADH_b PF12242.3 EPE26761.1 - 0.082 12.7 0.1 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EPE26761.1 - 0.084 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain POR PF01558.13 EPE26761.1 - 0.19 11.6 1.8 9.2 6.1 1.3 2.9 1 1 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase AIG2 PF06094.7 EPE26762.1 - 9.2e-09 35.7 0.0 2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 AIG2-like family Bac_rhamnosid PF05592.6 EPE26764.1 - 4e-173 576.2 0.0 5.2e-173 575.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EPE26764.1 - 5.7e-60 201.7 0.5 1.1e-59 200.8 0.3 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain WSC PF01822.14 EPE26765.1 - 5e-19 68.0 10.1 9.5e-19 67.1 7.0 1.5 1 0 0 1 1 1 1 WSC domain LacI PF00356.16 EPE26766.1 - 0.25 10.9 1.5 0.58 9.8 1.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family MFS_1 PF07690.11 EPE26767.1 - 8.3e-41 139.8 24.1 8.3e-41 139.8 16.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SecY PF00344.15 EPE26767.1 - 0.0017 17.3 5.1 0.0096 14.8 0.9 2.7 2 1 0 2 2 2 2 SecY translocase DUF4131 PF13567.1 EPE26767.1 - 0.0089 15.4 0.4 0.0089 15.4 0.3 3.7 3 1 0 4 4 4 1 Domain of unknown function (DUF4131) Corona_S2 PF01601.11 EPE26767.1 - 0.12 10.3 0.9 0.17 9.9 0.6 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein CorA PF01544.13 EPE26767.1 - 1.1 8.2 3.8 2.3 7.1 2.6 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IMS PF00817.15 EPE26768.1 - 1.6e-40 138.3 0.0 3.2e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EPE26768.1 - 8.7e-16 58.0 0.0 2.1e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EPE26768.1 - 1.4e-12 47.4 5.0 7.6e-07 29.0 0.1 3.6 4 0 0 4 4 4 2 Domain of unknown function (DUF4414) BRCT PF00533.21 EPE26768.1 - 5.9e-08 32.7 0.0 2.1e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EPE26768.1 - 3.4e-06 26.7 0.1 2e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 EPE26768.1 - 6.5e-05 22.7 0.0 0.00019 21.2 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain HHH_5 PF14520.1 EPE26768.1 - 0.009 16.1 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF1805 PF08827.6 EPE26768.1 - 0.052 13.3 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Cdd1 PF11731.3 EPE26768.1 - 0.088 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus HA2 PF04408.18 EPE26769.1 - 6.6e-19 67.8 0.2 6.6e-19 67.8 0.2 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EPE26769.1 - 3.7e-16 58.9 0.1 1.2e-15 57.2 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EPE26769.1 - 2.8e-12 46.3 0.0 6.6e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPE26769.1 - 4.9e-05 22.8 0.0 0.00023 20.7 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPE26769.1 - 0.0012 18.9 0.0 0.0059 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPE26769.1 - 0.017 14.6 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain KaiC PF06745.8 EPE26769.1 - 0.026 13.6 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 KaiC WD40 PF00400.27 EPE26771.1 - 2.1e-09 36.8 15.3 2.6e-07 30.2 0.4 6.1 7 0 0 7 7 7 2 WD domain, G-beta repeat PEGA PF08308.6 EPE26771.1 - 0.076 12.8 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 PEGA domain PD40 PF07676.7 EPE26771.1 - 0.099 12.3 0.6 1.9 8.2 0.1 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat LigB PF02900.13 EPE26772.1 - 3.7e-49 167.1 0.1 4.3e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short PF00106.20 EPE26773.1 - 0.00043 20.2 0.2 0.00088 19.2 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EPE26773.1 - 0.03 13.2 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 EPE26773.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 EPE26773.1 - 0.085 12.8 0.1 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding Fungal_trans_2 PF11951.3 EPE26774.1 - 1.2e-46 159.0 1.1 1.8e-46 158.4 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE26774.1 - 1.8e-06 27.7 9.0 1.8e-06 27.7 6.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPAP3_C PF13877.1 EPE26774.1 - 0.033 14.1 0.1 0.099 12.6 0.0 1.8 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 TauD PF02668.11 EPE26775.1 - 2.3e-25 89.7 0.0 3.1e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Complex1_LYR PF05347.10 EPE26776.1 - 3.5e-09 36.3 0.1 5.2e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPE26776.1 - 4.7e-08 33.1 0.1 8.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EPE26776.1 - 3.9e-06 27.2 0.1 5.7e-06 26.7 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Methyltransf_26 PF13659.1 EPE26777.1 - 7e-11 42.1 0.0 1.1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE26777.1 - 0.012 15.0 0.0 0.027 13.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain LSM PF01423.17 EPE26778.1 - 1.7e-15 56.3 0.0 2.2e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPE26778.1 - 0.0043 16.9 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2763 PF10961.3 EPE26778.1 - 6.2 7.2 11.3 12 6.4 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Pkr1 PF08636.5 EPE26779.1 - 2.8e-30 104.2 7.3 3.4e-30 103.9 5.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Pkinase PF00069.20 EPE26780.1 - 2.3e-48 164.6 0.0 6.3e-29 100.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE26780.1 - 1.5e-21 76.6 0.0 6.8e-15 54.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EPE26780.1 - 0.0035 17.1 0.2 0.0099 15.6 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family SDH_alpha PF03313.10 EPE26780.1 - 0.0092 15.0 0.8 0.016 14.2 0.5 1.3 1 0 0 1 1 1 1 Serine dehydratase alpha chain Pkinase_C PF00433.19 EPE26780.1 - 0.016 15.7 0.5 0.14 12.6 0.3 2.6 1 1 0 1 1 1 0 Protein kinase C terminal domain FKBP_C PF00254.23 EPE26781.1 - 3.5e-30 103.8 0.2 1.1e-29 102.2 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase FA_desaturase PF00487.19 EPE26781.1 - 1 8.7 1.7 1.5 8.2 1.2 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF4066 PF13278.1 EPE26782.1 - 1.2e-14 53.9 0.0 1.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EPE26782.1 - 2.8e-06 26.8 0.0 3.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GTP_EFTU PF00009.22 EPE26783.1 - 7.6e-10 38.5 0.0 2.8e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EPE26783.1 - 0.1 12.1 0.4 0.27 10.8 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SNARE PF05739.14 EPE26784.1 - 1.7e-05 24.4 1.5 1.7e-05 24.4 1.0 2.6 2 0 0 2 2 2 1 SNARE domain V-SNARE_C PF12352.3 EPE26784.1 - 0.054 13.5 3.2 0.43 10.6 0.2 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus KRTAP PF11759.3 EPE26784.1 - 3.4 7.9 22.5 2.3 8.5 3.3 2.9 1 1 1 2 2 2 0 Keratin-associated matrix TPR_16 PF13432.1 EPE26786.1 - 0.028 15.0 0.0 0.68 10.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Nro1 PF12753.2 EPE26786.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Vezatin PF12632.2 EPE26787.1 - 4.7e-49 166.7 0.0 7.6e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes CHASE3 PF05227.8 EPE26787.1 - 0.033 13.8 3.9 12 5.5 0.0 3.6 3 0 0 3 3 3 0 CHASE3 domain Vpu PF00558.14 EPE26787.1 - 0.7 9.4 0.0 0.7 9.4 0.0 2.4 3 0 0 3 3 3 0 Vpu protein Cullin PF00888.17 EPE26788.1 - 5e-47 160.7 0.0 1e-46 159.6 0.0 1.4 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EPE26788.1 - 2e-20 72.7 0.5 4.5e-20 71.6 0.4 1.6 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 zf-RING_2 PF13639.1 EPE26789.1 - 3.5e-12 45.9 2.2 6.6e-12 45.0 1.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPE26789.1 - 6.6e-11 42.1 0.6 1.2e-10 41.3 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPE26789.1 - 1.1e-06 28.5 2.9 2.6e-06 27.3 2.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE26789.1 - 6.2e-06 25.8 1.8 1e-05 25.1 1.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPE26789.1 - 9.1e-06 25.4 0.2 1.8e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EPE26789.1 - 1.4e-05 24.6 2.4 2.6e-05 23.7 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE26789.1 - 5.7e-05 22.7 0.7 9.8e-05 21.9 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPE26789.1 - 0.00082 19.0 1.1 0.0022 17.6 0.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 EPE26789.1 - 0.012 15.6 3.4 0.24 11.3 2.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 EPE26789.1 - 0.068 12.7 1.0 0.17 11.4 0.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_RING PF05883.6 EPE26789.1 - 0.26 11.1 0.6 0.46 10.3 0.4 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 EPE26789.1 - 2.5 8.0 4.3 0.48 10.3 0.4 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Voltage_CLC PF00654.15 EPE26790.1 - 0.14 11.1 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel Sporozoite_P67 PF05642.6 EPE26790.1 - 2.9 5.6 5.0 3.7 5.2 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen APH PF01636.18 EPE26791.1 - 2.4e-40 138.7 0.0 5.4e-40 137.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPE26791.1 - 0.00052 19.4 0.1 0.0015 17.9 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EPE26791.1 - 0.0023 17.0 0.0 0.0062 15.6 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EPE26791.1 - 0.0049 16.0 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EPE26791.1 - 0.0057 15.3 0.0 0.061 11.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) DUF928 PF06051.7 EPE26791.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) WD40 PF00400.27 EPE26792.1 - 2e-67 220.8 25.5 1.3e-08 34.3 0.1 12.0 13 0 0 13 13 13 10 WD domain, G-beta repeat Utp12 PF04003.7 EPE26792.1 - 4.2e-18 65.2 0.8 7.1e-18 64.5 0.6 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EPE26792.1 - 0.00029 19.6 3.9 0.52 9.0 0.1 4.9 2 2 2 5 5 5 2 Nup133 N terminal like Nup160 PF11715.3 EPE26792.1 - 0.00043 18.5 3.5 0.38 8.8 0.0 4.6 3 2 2 5 5 5 3 Nucleoporin Nup120/160 U3_assoc_6 PF08640.6 EPE26793.1 - 3.8e-28 97.0 0.3 1.4e-26 92.0 0.1 2.3 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 CENP-R PF06729.7 EPE26794.1 - 0.086 12.5 0.1 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinetochore component, CENP-R DHH PF01368.15 EPE26795.1 - 7.9e-09 35.3 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 DHH family CTK3_C PF12350.3 EPE26796.1 - 0.01 15.8 1.5 0.018 15.0 1.1 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus Adenylate_cycl PF01295.13 EPE26797.1 - 0.0017 16.7 0.2 0.0028 16.0 0.1 1.3 2 0 0 2 2 2 1 Adenylate cyclase, class-I Abhydrolase_6 PF12697.2 EPE26798.1 - 1.9e-27 96.6 0.0 2.9e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE26798.1 - 1.2e-12 47.8 0.0 1.7e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE26798.1 - 2.5e-06 27.3 0.0 1.2e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EPE26798.1 - 0.047 12.1 0.0 0.26 9.7 0.0 1.9 2 0 0 2 2 2 0 Ndr family Hydrolase_4 PF12146.3 EPE26798.1 - 0.051 13.4 0.0 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 Putative lysophospholipase bZIP_2 PF07716.10 EPE26799.1 - 0.0075 16.0 5.1 0.0083 15.9 2.3 1.9 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EPE26799.1 - 0.0095 15.8 4.5 0.015 15.2 2.3 1.9 1 1 1 2 2 2 1 bZIP transcription factor Ovate PF04844.8 EPE26799.1 - 0.046 13.5 0.2 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Transcriptional repressor, ovate FTA4 PF13093.1 EPE26799.1 - 0.28 10.5 4.3 0.44 9.9 3.0 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Chromate_transp PF02417.10 EPE26800.1 - 3.1e-54 183.1 36.9 6.3e-33 113.7 8.7 2.4 2 0 0 2 2 2 2 Chromate transporter Kinesin PF00225.18 EPE26801.1 - 1.5e-66 224.3 0.1 5.1e-57 193.0 0.0 2.3 1 1 1 2 2 2 2 Kinesin motor domain HHH_3 PF12836.2 EPE26801.1 - 4.4e-05 23.3 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.18 EPE26801.1 - 0.0082 15.7 0.0 4.9 7.0 0.0 3.0 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 EPE26801.1 - 0.025 14.7 0.0 3.2 8.0 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain LNP1 PF15419.1 EPE26801.1 - 0.9 9.6 8.9 0.03 14.4 1.7 1.8 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 MFS_1 PF07690.11 EPE26802.1 - 1.4e-34 119.3 66.7 2.3e-26 92.3 25.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26802.1 - 4.3e-09 35.4 34.0 3.7e-06 25.7 10.4 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EPE26802.1 - 0.0074 16.0 4.8 0.019 14.7 2.6 2.3 2 0 0 2 2 2 1 MFS_1 like family OapA_N PF08525.6 EPE26802.1 - 7.6 6.4 7.8 0.3 10.9 0.6 2.3 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif AIM24 PF01987.12 EPE26803.1 - 1.6e-47 161.7 0.0 2.1e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 EPE26803.1 - 0.013 15.9 0.1 0.11 12.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4402) ABC_tran PF00005.22 EPE26804.1 - 3.2e-34 118.1 0.0 5.7e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EPE26804.1 - 1e-33 116.9 9.7 1.5e-33 116.4 6.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EPE26804.1 - 1.6e-06 27.5 0.0 0.00075 18.7 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE26804.1 - 2.2e-06 27.8 0.0 0.018 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPE26804.1 - 9.9e-05 22.4 0.0 0.00034 20.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPE26804.1 - 0.00084 19.4 0.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPE26804.1 - 0.00092 20.0 0.0 0.0025 18.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EPE26804.1 - 0.0016 18.3 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPE26804.1 - 0.0039 17.3 0.0 0.048 13.8 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EPE26804.1 - 0.0039 16.3 0.0 0.0081 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPE26804.1 - 0.007 15.8 0.1 0.021 14.3 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EPE26804.1 - 0.0075 16.2 0.1 0.27 11.1 0.0 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase MobB PF03205.9 EPE26804.1 - 0.028 14.1 0.1 0.4 10.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EPE26804.1 - 0.036 14.3 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EPE26804.1 - 0.051 13.0 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 EPE26804.1 - 0.062 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EPE26804.1 - 0.16 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SbcCD_C PF13558.1 EPE26804.1 - 0.37 10.7 1.9 1 9.2 0.3 2.4 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit MAM33 PF02330.11 EPE26806.1 - 7.3e-31 107.5 0.1 1e-30 107.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF2962 PF11176.3 EPE26807.1 - 9.9e-50 168.1 1.5 1.1e-49 167.9 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) HTH_32 PF13565.1 EPE26807.1 - 0.33 11.7 5.5 1 10.2 0.1 2.3 1 1 1 2 2 2 0 Homeodomain-like domain XPG_I PF00867.13 EPE26808.1 - 3.6e-25 87.8 0.1 8.2e-25 86.6 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EPE26808.1 - 1.3e-22 79.9 0.0 2.7e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EPE26808.1 - 0.0019 17.7 0.0 0.0038 16.7 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing IBR PF01485.16 EPE26809.1 - 7.3e-23 80.2 50.0 3.3e-12 46.0 4.9 4.6 3 1 1 4 4 4 3 IBR domain zf-C3HC4 PF00097.20 EPE26809.1 - 9.8e-06 25.1 42.9 0.00088 18.8 4.2 4.7 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE26809.1 - 1.7e-05 24.7 7.8 1.7e-05 24.7 5.4 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE26809.1 - 0.00047 19.9 46.4 0.0026 17.5 6.5 3.7 2 1 1 3 3 3 2 Ring finger domain UN_NPL4 PF11543.3 EPE26809.1 - 0.01 16.1 0.4 0.035 14.3 0.0 2.2 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 zf-RING_5 PF14634.1 EPE26809.1 - 0.011 15.4 12.0 0.011 15.4 8.3 3.8 3 1 1 4 4 4 0 zinc-RING finger domain AceK PF06315.6 EPE26809.1 - 0.039 12.2 3.9 0.058 11.6 2.7 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) zf-C3HC4_4 PF15227.1 EPE26809.1 - 0.76 9.7 35.4 0.15 11.9 3.6 4.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Redoxin PF08534.5 EPE26810.1 - 5.5e-29 100.5 0.0 6.5e-29 100.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin BNR_2 PF13088.1 EPE26811.1 - 9.7e-07 28.3 0.3 0.002 17.4 0.1 2.7 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EPE26811.1 - 0.12 12.2 10.2 0.34 10.9 0.1 3.9 4 0 0 4 4 4 0 BNR/Asp-box repeat Fig1 PF12351.3 EPE26812.1 - 5.7e-56 189.2 4.3 5.7e-56 189.2 3.0 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EPE26812.1 - 4e-09 36.3 10.1 5.4e-09 35.9 7.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EPE26812.1 - 4.8e-05 22.4 6.1 4.8e-05 22.4 4.2 2.0 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 EPE26812.1 - 0.099 12.8 12.2 0.19 11.9 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF202) MLTD_N PF06474.7 EPE26812.1 - 0.14 12.3 2.6 0.76 10.0 1.8 2.3 1 0 0 1 1 1 0 MltD lipid attachment motif DUF4064 PF13273.1 EPE26812.1 - 2.2 8.4 19.0 0.19 11.8 0.9 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Drc1-Sld2 PF11719.3 EPE26813.1 - 1.2e-101 340.9 24.3 1.5e-101 340.6 16.8 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein zf-RING_2 PF13639.1 EPE26814.1 - 2.4e-07 30.4 9.6 4.1e-07 29.7 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPE26814.1 - 2.5e-07 30.2 5.5 3.7e-07 29.7 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE26814.1 - 9.5e-07 28.7 6.5 1.5e-06 28.0 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE26814.1 - 6.9e-06 25.6 5.4 1.2e-05 24.8 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE26814.1 - 0.0086 16.1 8.2 0.033 14.3 5.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger YdjO PF14169.1 EPE26814.1 - 0.029 13.8 0.9 0.2 11.1 0.0 2.4 2 0 0 2 2 2 0 Cold-inducible protein YdjO GAGA PF09237.6 EPE26814.1 - 0.049 13.2 1.7 0.36 10.4 0.0 2.8 3 0 0 3 3 3 0 GAGA factor DUF2384 PF09722.5 EPE26814.1 - 0.15 11.9 0.3 12 5.8 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2384) F-box-like_2 PF13013.1 EPE26815.1 - 0.0076 15.9 0.1 0.013 15.1 0.1 1.5 1 1 0 1 1 1 1 F-box-like domain Mito_carr PF00153.22 EPE26816.1 - 1.6e-64 213.6 4.4 2e-22 78.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WSC PF01822.14 EPE26817.1 - 1.5e-12 47.2 12.1 3e-12 46.2 8.4 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 EPE26817.1 - 0.00011 21.3 1.4 0.00011 21.3 1.0 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain G_glu_transpept PF01019.16 EPE26817.1 - 0.041 12.3 0.8 0.065 11.7 0.6 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase DUF4366 PF14283.1 EPE26817.1 - 0.056 12.8 0.3 0.085 12.2 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF2627 PF11118.3 EPE26817.1 - 0.098 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) OppC_N PF12911.2 EPE26817.1 - 0.17 11.2 0.2 0.33 10.3 0.1 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C MatE PF01554.13 EPE26817.1 - 1.6 8.3 8.6 3.2 7.3 0.1 2.4 2 0 0 2 2 2 0 MatE Toxin_3 PF00537.13 EPE26817.1 - 1.7 8.6 9.5 0.37 10.6 2.3 2.3 2 0 0 2 2 2 0 Scorpion toxin-like domain RINT1_TIP1 PF04437.8 EPE26818.1 - 1.9e-89 300.5 0.0 2.4e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DNA_ligase_A_M PF01068.16 EPE26819.1 - 2.1e-48 164.3 0.1 7.6e-46 156.0 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPE26819.1 - 9.2e-42 142.8 0.0 2e-41 141.7 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPE26819.1 - 3.5e-19 68.9 0.0 6.8e-18 64.8 0.0 3.1 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region FTHFS PF01268.14 EPE26819.1 - 0.1 10.5 0.0 3.6 5.4 0.0 2.1 2 0 0 2 2 2 0 Formate--tetrahydrofolate ligase CorA PF01544.13 EPE26821.1 - 0.085 11.8 0.2 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Asp PF00026.18 EPE26823.1 - 2.3e-107 358.9 0.2 2.7e-107 358.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPE26823.1 - 9.2e-13 48.4 0.0 4.7e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EPE26823.1 - 2.4e-06 27.9 0.0 0.069 13.6 0.0 3.1 2 2 1 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EPE26823.1 - 2.1e-05 24.1 0.0 0.00022 20.8 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EPE26823.1 - 0.08 12.7 0.1 16 5.3 0.0 3.1 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Alpha-amylase_C PF02806.13 EPE26823.1 - 0.13 12.4 0.0 0.41 10.8 0.0 1.9 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Pkinase PF00069.20 EPE26827.1 - 1.1e-51 175.5 0.1 1.6e-51 174.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE26827.1 - 8.5e-24 84.0 0.4 2.2e-23 82.6 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EPE26827.1 - 0.0038 16.0 0.0 0.0059 15.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase TMA7 PF09072.5 EPE26828.1 - 8.7e-21 74.1 19.2 9.8e-21 73.9 13.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 adh_short PF00106.20 EPE26829.1 - 1.1e-32 113.1 0.8 1.7e-32 112.6 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE26829.1 - 7.4e-27 94.6 0.2 1.2e-26 94.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE26829.1 - 5.7e-16 58.6 0.1 8.7e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EPE26829.1 - 0.0073 15.9 0.9 0.01 15.5 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EPE26829.1 - 0.032 14.0 0.4 0.058 13.2 0.3 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.13 EPE26829.1 - 0.087 12.8 0.3 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain RINGv PF12906.2 EPE26831.1 - 9.8e-07 28.7 4.7 1.7e-06 27.9 3.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EPE26831.1 - 8.3e-05 22.3 4.0 0.00014 21.6 2.8 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EPE26831.1 - 0.025 14.5 2.6 0.052 13.5 1.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.2 EPE26831.1 - 0.59 10.2 4.4 1.3 9.1 3.0 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger Fringe PF02434.11 EPE26832.1 - 2.6e-09 36.7 0.1 6.5e-09 35.3 0.1 1.6 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.7 EPE26832.1 - 3e-09 36.4 1.2 5.4e-09 35.6 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Meth_synt_2 PF01717.13 EPE26833.1 - 2.5e-15 56.2 0.0 1.3e-09 37.4 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EPE26833.1 - 7.4e-05 22.1 0.3 0.082 12.1 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Fungal_trans PF04082.13 EPE26835.1 - 1.9e-19 69.5 0.8 3.1e-19 68.8 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE26835.1 - 4e-08 33.0 12.1 4e-08 33.0 8.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 EPE26836.1 - 7.8e-54 182.4 0.0 1.1e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glycos_transf_2 PF00535.21 EPE26837.1 - 2.2e-29 102.3 0.0 2.8e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EPE26837.1 - 1e-10 41.8 0.0 2.1e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EPE26837.1 - 6.4e-09 35.2 0.0 8.4e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EPE26837.1 - 0.0028 16.9 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 FAD_binding_4 PF01565.18 EPE26839.1 - 2.7e-25 88.4 1.8 6e-25 87.3 0.7 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPE26839.1 - 0.008 16.0 1.6 0.012 15.4 0.5 1.8 2 0 0 2 2 2 1 Berberine and berberine like TPR_19 PF14559.1 EPE26840.1 - 2.5e-06 27.7 3.7 0.0036 17.6 0.2 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPE26840.1 - 0.00059 19.5 3.3 0.63 10.1 0.4 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE26840.1 - 0.0011 19.3 2.2 14 6.6 0.0 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPE26840.1 - 0.0024 17.7 5.0 0.053 13.4 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPE26840.1 - 0.0031 17.1 1.5 0.4 10.3 0.0 3.1 2 1 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 EPE26840.1 - 0.0087 16.7 7.3 0.64 10.7 0.0 4.1 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPE26840.1 - 0.012 15.2 1.6 0.65 9.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EPE26840.1 - 0.044 13.6 1.7 5.9 6.8 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EPE26840.1 - 0.06 13.4 0.5 35 4.6 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2240 PF09999.4 EPE26840.1 - 0.12 11.7 0.1 0.45 9.9 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) TPR_17 PF13431.1 EPE26840.1 - 0.14 12.4 1.2 3.7 7.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF605 PF04652.11 EPE26840.1 - 0.42 9.9 9.9 0.64 9.3 6.9 1.1 1 0 0 1 1 1 0 Vta1 like GalKase_gal_bdg PF10509.4 EPE26841.1 - 1.2e-20 72.5 0.0 2.3e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EPE26841.1 - 4.2e-14 52.3 2.5 1.5e-13 50.6 1.7 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPE26841.1 - 1.9e-13 50.4 0.0 5.3e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r3 PF04539.11 EPE26841.1 - 0.24 11.3 1.0 3 7.7 0.2 2.3 2 0 0 2 2 2 0 Sigma-70 region 3 TPP_enzyme_N PF02776.13 EPE26842.1 - 1.1e-54 184.5 0.1 2.8e-54 183.1 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EPE26842.1 - 2.5e-49 166.7 0.1 1.3e-47 161.1 0.0 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPE26842.1 - 7.2e-36 122.9 1.0 2.8e-35 121.0 0.3 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPR_18 PF13512.1 EPE26844.1 - 0.024 14.6 1.3 0.034 14.1 0.9 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat Bcr-Abl_Oligo PF09036.5 EPE26844.1 - 0.076 12.9 3.0 0.12 12.3 1.0 2.0 1 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF724 PF05266.9 EPE26844.1 - 0.3 10.6 4.0 0.15 11.6 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) ATP-synt_F6 PF05511.6 EPE26844.1 - 0.77 9.6 3.5 0.32 10.9 0.4 1.9 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 GAS PF13851.1 EPE26844.1 - 1.2 8.2 9.8 0.18 11.0 2.8 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding adh_short PF00106.20 EPE26845.1 - 6.7e-29 100.9 0.1 8.9e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE26845.1 - 1.6e-16 60.5 0.0 2.3e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE26845.1 - 2.7e-16 60.0 0.0 3.5e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EPE26845.1 - 1.4e-05 24.1 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EPE26845.1 - 2e-05 24.1 0.0 3.2e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 EPE26845.1 - 0.02 14.3 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Eno-Rase_NADH_b PF12242.3 EPE26845.1 - 0.023 14.4 1.6 0.044 13.5 1.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EPE26845.1 - 0.099 12.7 0.1 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NST1 PF13945.1 EPE26846.1 - 2e-61 207.4 0.7 2e-61 207.4 0.5 4.9 2 2 3 5 5 5 1 Salt tolerance down-regulator Ras PF00071.17 EPE26847.1 - 1.2e-46 158.1 0.0 1.3e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE26847.1 - 7.5e-14 52.2 0.0 1.1e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE26847.1 - 1.4e-05 24.3 0.0 5.3e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPE26847.1 - 0.0065 15.6 0.0 0.0081 15.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EPE26847.1 - 0.0097 15.3 0.0 1.4 8.4 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EPE26847.1 - 0.078 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPE26847.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 EPE26847.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_U35_2 PF14550.1 EPE26847.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative phage protease XkdF MRP-L28 PF09812.4 EPE26848.1 - 3.1e-08 33.5 0.3 4.8e-08 32.9 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Inhibitor_Mig-6 PF11555.3 EPE26848.1 - 0.0092 16.3 1.0 0.02 15.2 0.7 1.6 1 0 0 1 1 1 1 EGFR receptor inhibitor Mig-6 DUF1749 PF08538.5 EPE26849.1 - 4.9e-94 314.6 0.0 5.8e-94 314.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 EPE26849.1 - 1.5e-05 24.7 0.0 6.4e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE26849.1 - 0.0017 18.2 0.0 0.0035 17.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EPE26849.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase LCAT PF02450.10 EPE26849.1 - 0.089 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DEAD PF00270.24 EPE26851.1 - 8.9e-46 155.4 0.0 1.4e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE26851.1 - 2.1e-26 91.5 0.0 4e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE26851.1 - 0.00056 19.7 0.0 0.0021 17.8 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EPE26851.1 - 0.051 13.3 0.4 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Part of AAA domain Brix PF04427.13 EPE26852.1 - 1.1e-56 191.5 0.0 1.6e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain HD_4 PF13328.1 EPE26852.1 - 0.3 10.7 2.0 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 HD domain YqzE PF14038.1 EPE26852.1 - 3.4 7.4 5.9 14 5.4 4.1 2.1 1 0 0 1 1 1 0 YqzE-like protein Syntaphilin PF15290.1 EPE26854.1 - 0.18 11.2 6.1 0.11 11.9 2.9 1.6 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp CoA_transf_3 PF02515.12 EPE26855.1 - 1.6e-59 200.3 0.0 3.2e-59 199.4 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.24 EPE26856.1 - 5.9e-09 35.4 7.0 9.4e-09 34.8 4.8 1.3 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EPE26856.1 - 0.00036 20.2 4.0 0.00075 19.1 0.8 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EPE26856.1 - 0.00045 19.4 3.9 0.00045 19.4 2.7 2.3 2 1 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.1 EPE26856.1 - 0.0057 15.9 2.4 0.0057 15.9 1.7 1.7 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 EPE26856.1 - 0.079 12.7 1.4 0.17 11.6 1.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.6 EPE26856.1 - 2.5 7.8 4.4 0.85 9.3 0.8 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Peroxidase_2 PF01328.12 EPE26857.1 - 9.5e-12 44.2 0.0 1.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 GFA PF04828.9 EPE26858.1 - 1.6e-15 56.7 0.8 2.4e-15 56.2 0.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme C1_1 PF00130.17 EPE26858.1 - 0.13 12.0 3.8 5.1 6.9 1.4 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lum_binding PF00677.12 EPE26860.1 - 5.1e-39 132.0 0.6 3.9e-21 74.7 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain DUF411 PF04214.8 EPE26860.1 - 0.012 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF AcetylCoA_hydro PF02550.10 EPE26860.1 - 0.061 13.0 0.2 0.2 11.3 0.1 1.8 1 1 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain YabP PF07873.6 EPE26860.1 - 0.1 12.1 0.0 4.5 6.8 0.0 3.1 2 1 1 3 3 3 0 YabP family Per1 PF04080.8 EPE26861.1 - 8.6e-106 353.2 10.1 1.2e-105 352.7 7.0 1.2 1 0 0 1 1 1 1 Per1-like Cellulase PF00150.13 EPE26861.1 - 0.001 18.3 0.0 0.002 17.3 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) tRNA-synt_2b PF00587.20 EPE26862.1 - 2.3e-31 108.6 0.0 3.7e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPE26862.1 - 3.2e-11 43.0 0.0 6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.12 EPE26863.1 - 3.5e-45 153.3 0.0 9.9e-45 151.9 0.0 1.9 1 0 0 1 1 1 1 CBF/Mak21 family APS_kinase PF01583.15 EPE26865.1 - 4e-69 231.2 0.0 6e-69 230.6 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase 4HBT PF03061.17 EPE26865.1 - 1.1e-10 41.4 0.0 2.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily AAA_33 PF13671.1 EPE26865.1 - 7.6e-05 22.6 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE26865.1 - 0.00042 21.1 0.0 0.00089 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPE26865.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPE26865.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.5 EPE26865.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 V-ATPase_C PF03223.10 EPE26866.1 - 1.8e-119 398.9 0.1 2e-119 398.8 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 EPE26866.1 - 0.098 12.9 0.7 0.59 10.4 0.0 2.4 3 0 0 3 3 3 0 mRNA capping enzyme, C-terminal domain IU_nuc_hydro PF01156.14 EPE26868.1 - 2.5e-47 161.6 0.1 3.2e-47 161.2 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF726 PF05277.7 EPE26870.1 - 0.091 11.6 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) GMC_oxred_N PF00732.14 EPE26872.1 - 1.8e-55 188.1 0.0 2.4e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE26872.1 - 1.2e-32 113.1 0.1 2.2e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EPE26872.1 - 0.00074 19.4 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE26872.1 - 0.0013 17.6 0.0 0.11 11.3 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE26872.1 - 0.0022 16.9 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EPE26872.1 - 0.059 11.8 0.0 0.8 8.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EPE26872.1 - 0.066 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EPE26872.1 - 0.099 11.2 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 EPE26872.1 - 0.11 11.6 0.1 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family BAH PF01426.13 EPE26873.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 BAH domain Mod_r PF07200.8 EPE26874.1 - 6.2e-10 39.1 4.7 9.4e-10 38.5 3.2 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein AAA_32 PF13654.1 EPE26874.1 - 0.046 12.3 0.6 0.064 11.9 0.4 1.1 1 0 0 1 1 1 0 AAA domain F-box PF00646.28 EPE26876.1 - 0.00079 19.0 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE26876.1 - 0.066 12.9 0.1 0.066 12.9 0.0 2.0 2 0 0 2 2 2 0 F-box-like Nup84_Nup100 PF04121.8 EPE26878.1 - 3.4e-80 269.6 0.2 3.4e-80 269.6 0.2 1.7 2 1 0 2 2 2 1 Nuclear pore protein 84 / 107 Rad60-SLD PF11976.3 EPE26879.1 - 2.2e-20 72.1 0.0 2.8e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EPE26879.1 - 1.7e-08 33.7 0.0 2.2e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family NAM-associated PF14303.1 EPE26880.1 - 0.047 14.0 8.7 0.071 13.4 6.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Ligase_CoA PF00549.14 EPE26881.1 - 2.3e-34 118.2 2.9 1.1e-18 67.3 0.8 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EPE26881.1 - 6.9e-16 58.5 2.2 9.7e-16 58.0 0.2 2.4 2 1 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 EPE26881.1 - 2e-08 33.9 0.1 0.00035 20.1 0.0 2.8 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 EPE26881.1 - 0.0026 17.1 0.0 0.026 13.9 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Aa_trans PF01490.13 EPE26882.1 - 1.1e-27 96.6 35.9 1.8e-27 95.8 24.9 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein OSTbeta PF15048.1 EPE26882.1 - 0.05 13.6 0.0 0.05 13.6 0.0 1.7 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein BRX_N PF13713.1 EPE26883.1 - 0.094 12.1 0.5 0.49 9.8 0.0 2.3 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain HD PF01966.17 EPE26884.1 - 5.5e-05 23.1 0.0 9.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 HD domain LIM PF00412.17 EPE26885.1 - 1.4e-22 79.5 36.0 2.8e-08 33.7 4.5 3.6 4 0 0 4 4 4 3 LIM domain MFS_1 PF07690.11 EPE26886.1 - 2.5e-33 115.2 76.5 4.9e-26 91.2 33.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2681 PF10883.3 EPE26886.1 - 0.18 12.0 0.2 0.18 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Pmp3 PF01679.12 EPE26886.1 - 0.73 9.5 9.6 3 7.6 0.2 3.9 3 1 0 3 3 3 0 Proteolipid membrane potential modulator FAD_binding_4 PF01565.18 EPE26887.1 - 2.2e-17 62.8 2.4 3.9e-17 62.0 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE26887.1 - 1.1e-08 34.8 0.2 3.5e-08 33.2 0.2 2.0 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EPE26888.1 - 2.3e-17 62.7 1.9 5.7e-17 61.4 1.3 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE26888.1 - 7.1e-11 41.8 4.2 9.3e-11 41.4 0.6 2.7 3 0 0 3 3 3 1 Berberine and berberine like Cytokin-bind PF09265.5 EPE26888.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding UbiA PF01040.13 EPE26890.1 - 1.4e-21 76.8 8.9 1.8e-21 76.5 6.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family adh_short PF00106.20 EPE26891.1 - 7.9e-18 64.9 2.5 1.1e-17 64.5 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE26891.1 - 7.7e-09 35.4 0.4 1e-08 35.0 0.3 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPE26891.1 - 0.00023 20.1 0.0 0.00027 19.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EPE26891.1 - 0.0082 15.9 1.5 0.021 14.5 0.4 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EPE26891.1 - 0.01 15.9 0.1 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EPE26891.1 - 0.011 15.2 0.0 0.018 14.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GIDA PF01134.17 EPE26891.1 - 0.24 10.2 1.1 0.31 9.8 0.8 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A p450 PF00067.17 EPE26892.1 - 7.6e-37 126.9 0.0 9.9e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MIF4G PF02854.14 EPE26893.1 - 4e-23 81.9 0.1 9.2e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EPE26893.1 - 3.4e-22 78.2 0.9 9.7e-21 73.5 0.1 2.6 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.10 EPE26894.1 - 2e-25 88.5 0.0 3.5e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Rep_N PF08724.5 EPE26894.1 - 0.13 11.7 0.2 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Rep protein catalytic domain like RRM_1 PF00076.17 EPE26896.1 - 1.9e-48 161.9 0.0 2.7e-18 65.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE26896.1 - 5e-40 135.3 0.0 7e-15 54.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE26896.1 - 1e-22 79.7 0.0 1.2e-06 28.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPE26896.1 - 0.00012 21.8 0.0 0.42 10.4 0.0 3.4 3 0 0 3 3 3 1 RNA binding motif ATP-grasp_2 PF08442.5 EPE26896.1 - 0.00027 20.3 0.0 0.01 15.2 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Limkain-b1 PF11608.3 EPE26896.1 - 0.00032 20.3 0.1 6.6 6.5 0.0 4.0 3 2 0 3 3 3 1 Limkain b1 DUF1777 PF08648.7 EPE26896.1 - 0.11 12.2 15.5 0.19 11.4 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Corona_nucleoca PF00937.13 EPE26896.1 - 0.46 9.3 8.1 0.71 8.7 5.6 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein GRP PF07172.6 EPE26896.1 - 0.85 10.1 0.0 0.057 13.8 6.5 4.2 3 1 0 3 3 3 0 Glycine rich protein family Got1 PF04178.7 EPE26897.1 - 1.1e-31 109.3 14.5 1.5e-31 108.9 10.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family La PF05383.12 EPE26898.1 - 4.3e-18 64.8 0.9 7.1e-18 64.1 0.6 1.4 1 0 0 1 1 1 1 La domain FtsJ PF01728.14 EPE26899.1 - 1.9e-14 54.0 0.0 3.1e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Nol1_Nop2_Fmu PF01189.12 EPE26899.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 NOL1/NOP2/sun family Tetraspannin PF00335.15 EPE26901.1 - 0.15 11.3 3.1 0.07 12.4 0.4 1.7 2 0 0 2 2 2 0 Tetraspanin family DUF4118 PF13493.1 EPE26901.1 - 3.1 8.0 6.9 0.35 11.0 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) DUF4229 PF14012.1 EPE26901.1 - 4.7 7.1 5.8 2.6 8.0 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) PAP_assoc PF03828.14 EPE26902.1 - 2.8e-19 68.8 0.1 9.8e-19 67.0 0.1 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPE26902.1 - 5.3e-06 26.6 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain MFS_1 PF07690.11 EPE26904.1 - 1.4e-25 89.7 12.1 1.4e-25 89.7 8.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily AhpC-TSA_2 PF13911.1 EPE26905.1 - 1.7e-08 34.3 0.0 2.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EPE26905.1 - 5.3e-08 32.5 0.0 8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPE26905.1 - 4.7e-06 26.2 0.0 6.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin MIP PF00230.15 EPE26906.1 - 2.6e-42 144.8 13.7 3.7e-42 144.3 9.5 1.2 1 0 0 1 1 1 1 Major intrinsic protein GMC_oxred_N PF00732.14 EPE26908.1 - 1.6e-54 185.1 0.0 2.1e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE26908.1 - 3.7e-23 82.4 0.1 6.9e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EPE26908.1 - 0.065 12.0 0.9 8.6 5.0 0.4 2.2 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 EPE26908.1 - 0.074 11.9 0.2 3.1 6.6 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NUDIX PF00293.23 EPE26910.1 - 7.8e-06 25.5 0.0 1.6e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EPE26911.1 - 5.9e-18 64.8 0.1 1.3e-17 63.7 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain PI3_PI4_kinase PF00454.22 EPE26913.1 - 8.9e-49 166.0 0.0 1.7e-48 165.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EPE26913.1 - 7.9e-44 150.0 10.4 7.9e-44 150.0 7.2 1.7 2 0 0 2 2 2 1 FAT domain UME PF08064.8 EPE26913.1 - 5.9e-32 109.7 0.6 6.3e-31 106.5 0.0 3.1 4 0 0 4 4 4 1 UME (NUC010) domain FATC PF02260.15 EPE26913.1 - 1.1e-12 47.0 0.0 2.9e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 FATC domain COX16 PF14138.1 EPE26914.1 - 3.7e-32 110.3 0.1 5.2e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Dak1 PF02733.12 EPE26915.1 - 5.9e-112 373.4 0.1 8.9e-112 372.8 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EPE26915.1 - 2.3e-38 131.5 1.4 3.7e-38 130.9 0.9 1.3 1 0 0 1 1 1 1 DAK2 domain F-box-like PF12937.2 EPE26916.1 - 0.0022 17.6 0.4 2.4 7.9 0.0 3.0 2 1 0 2 2 2 2 F-box-like zf-PARP PF00645.13 EPE26917.1 - 7.1e-16 58.2 0.1 2.8e-15 56.3 0.1 2.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Med17 PF10156.4 EPE26918.1 - 2.6e-96 322.7 0.3 3.2e-96 322.4 0.2 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.15 EPE26919.1 - 8.3e-160 530.2 3.6 1.1e-118 395.3 0.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase TgMIC1 PF11476.3 EPE26919.1 - 0.049 13.1 3.2 0.17 11.3 0.0 2.8 3 0 0 3 3 3 0 Toxoplasma gondii micronemal protein 1 TgMIC1 ISN1 PF06437.6 EPE26920.1 - 1.9e-192 639.4 0.0 2.2e-192 639.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase TORC_N PF12884.2 EPE26920.1 - 0.091 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus PG_binding_1 PF01471.13 EPE26920.1 - 0.12 12.3 0.1 25 4.9 0.0 2.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain DUF1691 PF07950.6 EPE26921.1 - 1.1e-39 134.7 9.1 2.2e-23 82.2 3.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Cytochrom_B559 PF00283.14 EPE26921.1 - 0.15 11.3 3.5 0.35 10.1 2.4 1.5 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Glyco_transf_15 PF01793.11 EPE26922.1 - 6.9e-141 468.9 4.8 8.4e-141 468.6 3.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase MFS_1 PF07690.11 EPE26923.1 - 5.9e-38 130.4 74.6 9.1e-32 110.1 33.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE26923.1 - 2.3e-09 36.3 41.2 3.7e-07 29.0 14.2 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EPE26923.1 - 2.7e-05 22.7 23.5 2.7e-05 22.7 16.3 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Arif-1 PF06770.6 EPE26923.1 - 0.49 9.7 5.2 0.093 12.0 0.4 2.2 2 1 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) Aldo_ket_red PF00248.16 EPE26924.1 - 1.7e-65 220.6 0.1 2e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UCR_TM PF02921.9 EPE26926.1 - 4.1e-21 74.9 0.8 7.3e-21 74.1 0.6 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EPE26926.1 - 5.3e-18 64.3 0.1 8.2e-18 63.7 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Cpn60_TCP1 PF00118.19 EPE26927.1 - 2.8e-143 478.0 16.0 3.2e-143 477.8 11.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.20 EPE26928.1 - 1.5e-20 73.5 0.0 3.4e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EPE26928.1 - 6.5e-20 70.8 0.9 1.5e-19 69.6 0.6 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EPE26928.1 - 2.9e-19 68.8 0.0 6.5e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Pkinase PF00069.20 EPE26929.1 - 2.4e-64 217.0 0.0 5e-64 215.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE26929.1 - 4e-37 127.7 0.0 7.2e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EPE26929.1 - 5.3e-31 106.1 22.8 1.2e-17 63.4 5.6 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EPE26929.1 - 1.6e-20 72.5 33.3 1e-11 44.3 7.6 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EPE26929.1 - 1.8e-13 50.7 2.8 5.7e-13 49.1 1.9 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPE26929.1 - 0.022 13.7 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Uds1 PF15456.1 EPE26929.1 - 3.1 7.8 12.8 1 9.3 1.0 2.6 2 0 0 2 2 2 0 Up-regulated During Septation DUF892 PF05974.7 EPE26929.1 - 3.9 7.2 9.8 0.19 11.5 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF892) DUF4449 PF14613.1 EPE26930.1 - 4.9e-05 23.3 0.1 4.9e-05 23.3 0.1 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) DUF1828 PF08861.5 EPE26930.1 - 0.0015 18.1 0.0 0.0067 16.0 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function DUF1828 Tricorn_C1 PF14684.1 EPE26930.1 - 0.0022 17.8 0.7 0.015 15.1 0.1 2.7 2 1 0 2 2 2 1 Tricorn protease C1 domain D5_N PF08706.6 EPE26930.1 - 0.072 13.1 0.7 0.31 11.1 0.5 2.2 1 1 0 1 1 1 0 D5 N terminal like Syntaxin-6_N PF09177.6 EPE26930.1 - 4.5 7.7 6.7 4.1 7.8 0.3 3.7 2 2 3 5 5 5 0 Syntaxin 6, N-terminal Zn_clus PF00172.13 EPE26931.1 - 0.062 13.2 7.8 0.11 12.4 5.4 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Elf1 PF05129.8 EPE26932.1 - 0.7 9.6 4.7 5.3 6.8 0.2 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like HypA PF01155.14 EPE26932.1 - 1.5 8.5 5.8 1.1 9.0 1.9 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2439 PF10382.4 EPE26933.1 - 3.1e-27 94.5 0.4 6.3e-27 93.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) SH3_1 PF00018.23 EPE26934.1 - 1.9e-14 52.7 0.1 3.2e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPE26934.1 - 2.8e-14 52.4 0.1 5.7e-14 51.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 EPE26934.1 - 2.5e-12 46.8 0.2 3.4e-12 46.3 0.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.12 EPE26934.1 - 3.2e-11 42.5 0.0 6.5e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Rsa3 PF14615.1 EPE26936.1 - 1.5e-18 65.7 0.1 2e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 NST1 PF13945.1 EPE26936.1 - 0.21 11.6 3.2 0.26 11.3 2.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Ribosomal_S10 PF00338.17 EPE26938.1 - 2.6e-30 104.1 0.6 3.1e-30 103.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.11 EPE26939.1 - 2.8e-10 39.4 0.1 5e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 CUE domain Gly-rich_Ago1 PF12764.2 EPE26939.1 - 8.2 7.1 6.9 26 5.5 4.8 1.9 1 0 0 1 1 1 0 Glycine-rich region of argonaut Inp1 PF12634.2 EPE26940.1 - 3e-32 111.2 0.1 1.1e-31 109.4 0.0 2.0 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 EPE26941.1 - 1.3e-09 37.8 8.1 3.7e-08 33.0 5.6 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SKG6 PF08693.5 EPE26941.1 - 0.41 10.0 7.6 47 3.4 5.3 2.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain FmdA_AmdA PF03069.10 EPE26942.1 - 1.1e-151 504.7 0.0 1.2e-151 504.5 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family PCI PF01399.22 EPE26943.1 - 3.2e-10 40.2 0.0 6.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain NAD_binding_10 PF13460.1 EPE26944.1 - 5.7e-19 68.8 0.0 7.8e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE26944.1 - 1e-15 57.6 0.0 1.3e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EPE26944.1 - 5.8e-14 52.1 0.0 1.1e-13 51.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE26944.1 - 1.1e-09 37.4 0.0 1.9e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EPE26944.1 - 6.9e-09 35.0 0.0 4.3e-07 29.1 0.0 2.8 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EPE26944.1 - 2.3e-06 26.7 0.2 0.0013 17.7 0.2 3.0 1 1 1 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 EPE26944.1 - 0.00071 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EPE26944.1 - 0.0012 18.8 0.0 0.023 14.5 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE26944.1 - 0.0072 16.0 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 1 KR domain DDE_Tnp_1_3 PF13612.1 EPE26944.1 - 0.047 13.4 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain HIM1 PF08732.5 EPE26944.1 - 0.063 11.7 0.0 0.094 11.1 0.0 1.2 1 0 0 1 1 1 0 HIM1 ApbA PF02558.11 EPE26944.1 - 0.094 12.1 0.0 0.5 9.7 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA N6-adenineMlase PF10237.4 EPE26945.1 - 3.9e-56 189.1 0.2 4.9e-56 188.8 0.1 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase UCH PF00443.24 EPE26946.1 - 1.4e-57 194.8 8.6 1.9e-57 194.4 5.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPE26946.1 - 1.8e-39 135.9 7.4 2.5e-39 135.5 5.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPE26946.1 - 0.00029 20.8 0.1 0.00029 20.8 0.1 2.5 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein TRAM_LAG1_CLN8 PF03798.11 EPE26947.1 - 3.9e-33 114.6 19.8 3.9e-33 114.6 13.7 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EPE26947.1 - 5.4e-25 86.6 0.2 1.1e-23 82.4 0.0 2.5 2 0 0 2 2 2 1 TRAM1-like protein PalH PF08733.5 EPE26948.1 - 3.3e-107 358.3 0.0 5.5e-107 357.6 0.0 1.3 1 1 0 1 1 1 1 PalH/RIM21 SH3_1 PF00018.23 EPE26949.1 - 1.3e-05 24.5 0.1 4.1e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EPE26949.1 - 0.0063 16.0 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF2410 PF10307.4 EPE26950.1 - 1.9e-78 262.3 0.0 2.7e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) HSF_DNA-bind PF00447.12 EPE26951.1 - 2.1e-38 130.6 0.4 3.6e-38 129.8 0.3 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EPE26951.1 - 4.2e-19 68.6 0.1 7.4e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Mito_carr PF00153.22 EPE26952.1 - 1.1e-47 159.7 3.7 1.3e-16 60.0 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Phage_holin_3 PF05106.7 EPE26952.1 - 0.035 14.0 0.3 2.1 8.4 0.1 2.6 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) Spp-24 PF07448.6 EPE26952.1 - 0.081 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) SNF2_N PF00176.18 EPE26953.1 - 1.5e-68 230.7 0.0 2.2e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EPE26953.1 - 2.9e-60 203.4 1.5 7e-60 202.1 1.1 1.7 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EPE26953.1 - 3.4e-13 49.2 0.0 2.3e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EPE26953.1 - 0.00055 18.8 0.0 0.003 16.4 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EPE26953.1 - 0.00072 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Hydrophobin PF01185.13 EPE26954.1 - 0.0002 21.7 3.3 0.00031 21.1 2.3 1.4 1 0 0 1 1 1 1 Fungal hydrophobin SURF6 PF04935.7 EPE26956.1 - 6.6e-50 169.3 42.0 6.6e-50 169.3 29.1 4.0 2 1 1 4 4 4 1 Surfeit locus protein 6 RRP14 PF15459.1 EPE26956.1 - 6e-21 74.2 2.8 6e-21 74.2 1.9 6.8 4 2 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 GPP34 PF05719.6 EPE26957.1 - 1.5e-66 224.4 0.2 1.8e-66 224.1 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.20 EPE26958.1 - 1.8e-09 37.7 0.3 2.4e-09 37.2 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EPE26958.1 - 2.7e-07 30.5 0.3 3.9e-07 30.0 0.2 1.1 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EPE26958.1 - 0.14 12.2 0.2 0.21 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Fer4 PF00037.22 EPE26959.1 - 9.3e-14 50.3 16.0 5.5e-08 32.0 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EPE26959.1 - 3.5e-12 46.5 10.5 5.8e-12 45.7 7.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EPE26959.1 - 5.4e-10 38.9 4.3 6.1e-05 22.8 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EPE26959.1 - 1.9e-09 37.1 22.1 5.9e-08 32.3 8.5 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EPE26959.1 - 2.1e-09 37.9 7.3 0.00021 21.9 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 EPE26959.1 - 2.7e-09 37.1 11.0 5.3e-09 36.2 7.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EPE26959.1 - 8.4e-08 31.6 14.2 0.00045 19.9 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EPE26959.1 - 9.7e-08 31.9 20.3 1.6e-05 24.8 7.9 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 EPE26959.1 - 2.5e-07 30.2 17.1 0.0013 18.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EPE26959.1 - 5.1e-06 26.3 12.7 0.00059 19.9 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EPE26959.1 - 5.7e-06 26.5 9.6 0.00085 19.6 7.8 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EPE26959.1 - 4.1e-05 23.9 9.8 0.014 15.8 0.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EPE26959.1 - 0.0076 16.6 15.0 0.31 11.4 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EPE26959.1 - 0.017 15.7 13.1 0.3 11.6 1.2 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EPE26959.1 - 0.067 13.7 16.9 0.16 12.5 2.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EPE26959.1 - 0.23 11.6 4.6 0.28 11.3 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain BTB PF00651.26 EPE26960.1 - 4e-10 39.6 0.0 7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain RPAP1_C PF08620.5 EPE26961.1 - 1.3e-28 98.6 0.3 2.8e-28 97.5 0.0 1.8 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EPE26961.1 - 9.2e-17 60.3 5.1 9.2e-17 60.3 3.5 2.2 2 0 0 2 2 2 1 RPAP1-like, N-terminal HEAT PF02985.17 EPE26961.1 - 0.14 12.3 0.1 0.69 10.1 0.0 2.2 2 0 0 2 2 2 0 HEAT repeat HUN PF08729.5 EPE26962.1 - 1.9e-13 50.0 0.1 5.3e-13 48.6 0.1 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Mito_carr PF00153.22 EPE26963.1 - 1.7e-56 187.9 3.3 1.3e-22 79.2 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Complex1_LYR PF05347.10 EPE26964.1 - 0.0081 15.9 0.0 0.078 12.7 0.0 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) TTSSLRR PF12468.3 EPE26964.1 - 0.06 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein DUF2370 PF10176.4 EPE26965.1 - 2.2e-88 295.5 1.6 3.1e-88 295.0 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2370) DUF2561 PF10812.3 EPE26965.1 - 0.058 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) PCMT PF01135.14 EPE26966.1 - 4.5e-58 196.2 0.0 5.7e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EPE26966.1 - 4.5e-08 33.6 0.1 7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE26966.1 - 0.0001 21.9 0.1 0.0002 21.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE26966.1 - 0.00027 20.6 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPE26966.1 - 0.00069 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE26966.1 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EPE26966.1 - 0.019 15.8 0.1 0.048 14.4 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EPE26966.1 - 0.062 12.4 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EPE26966.1 - 0.068 12.1 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.7 EPE26966.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UCH PF00443.24 EPE26968.1 - 2.6e-42 144.7 0.0 4.9e-42 143.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EPE26968.1 - 8.5e-35 117.9 4.5 3.6e-11 42.3 0.0 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 EPE26968.1 - 5.2e-15 55.6 0.0 1.2e-06 28.2 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pox_A_type_inc PF04508.7 EPE26968.1 - 0.014 15.1 0.5 0.066 13.0 0.3 2.3 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF948 PF06103.6 EPE26968.1 - 0.069 13.0 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tim17 PF02466.14 EPE26969.1 - 1.5e-12 47.7 8.1 1.3e-11 44.6 3.0 2.1 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family TBCC PF07986.7 EPE26970.1 - 5.4e-32 109.7 0.5 8.4e-32 109.0 0.4 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF2937 PF11157.3 EPE26970.1 - 0.095 12.0 0.1 7.1 5.9 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) Med9 PF07544.8 EPE26971.1 - 2.5e-20 71.9 0.4 4.1e-20 71.2 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.5 EPE26971.1 - 0.013 15.6 0.1 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 EPE26971.1 - 0.024 14.4 0.2 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 EPE26971.1 - 0.05 13.9 0.7 0.11 12.8 0.5 1.6 1 0 0 1 1 1 0 SlyX Med21 PF11221.3 EPE26971.1 - 0.054 13.4 3.2 0.063 13.2 2.2 1.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF1090 PF06476.7 EPE26971.1 - 0.1 12.2 4.2 0.13 11.9 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) IncA PF04156.9 EPE26971.1 - 0.11 12.1 0.8 0.14 11.7 0.5 1.1 1 0 0 1 1 1 0 IncA protein SNARE PF05739.14 EPE26971.1 - 0.24 11.1 2.4 0.59 9.8 1.1 1.9 2 0 0 2 2 2 0 SNARE domain zf-C4H2 PF10146.4 EPE26971.1 - 1.4 8.9 5.3 0.32 10.9 1.6 1.5 1 1 1 2 2 2 0 Zinc finger-containing protein iPGM_N PF06415.8 EPE26972.1 - 1.8e-72 243.3 0.0 2.3e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 EPE26972.1 - 4.5e-70 235.9 0.1 5.2e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EPE26972.1 - 4e-06 26.2 0.0 1.6e-05 24.2 0.0 1.7 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EPE26972.1 - 1.3e-05 24.6 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase ketoacyl-synt PF00109.21 EPE26975.1 - 1.3e-71 241.0 0.0 3e-71 239.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EPE26975.1 - 2e-58 197.0 0.0 5.4e-58 195.6 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EPE26975.1 - 6.8e-56 189.9 1.8 5.5e-55 186.9 0.0 2.8 3 0 0 3 3 3 1 Acyl transferase domain adh_short PF00106.20 EPE26975.1 - 1.3e-45 155.3 0.1 6.7e-45 152.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EPE26975.1 - 1.4e-42 145.8 0.0 2.5e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EPE26975.1 - 1.4e-39 134.6 0.0 3.3e-39 133.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EPE26975.1 - 4.1e-17 61.9 0.0 1.2e-16 60.4 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EPE26975.1 - 3e-16 59.7 0.0 8e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE26975.1 - 5.9e-12 45.5 0.0 1.6e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EPE26975.1 - 2.1e-10 41.5 0.0 1.3e-09 39.0 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EPE26975.1 - 3.8e-10 39.5 0.0 9.4e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE26975.1 - 6.6e-09 36.3 0.0 2.5e-08 34.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EPE26975.1 - 7.6e-09 35.3 0.2 2.1e-08 33.8 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EPE26975.1 - 4.1e-06 26.9 0.2 8.3e-05 22.7 0.0 2.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EPE26975.1 - 1.3e-05 25.5 0.0 4.1e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE26975.1 - 0.0011 19.2 0.0 0.014 15.7 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 EPE26975.1 - 0.0015 18.0 0.0 0.0034 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 EPE26975.1 - 0.0033 16.4 0.0 0.027 13.4 0.0 2.2 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EPE26975.1 - 0.013 14.6 0.0 0.044 12.8 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family NmrA PF05368.8 EPE26975.1 - 0.018 14.3 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Methyltransf_26 PF13659.1 EPE26975.1 - 0.038 14.0 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 EPE26975.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Polysacc_synt_2 PF02719.10 EPE26975.1 - 0.06 12.2 0.0 0.14 11.0 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EPE26976.1 - 7e-42 143.3 41.6 2.7e-41 141.4 28.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE26976.1 - 1.2e-14 53.5 18.4 1.5e-14 53.1 12.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE26976.1 - 7.1e-12 44.6 7.4 7.1e-12 44.6 5.1 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Abhydrolase_3 PF07859.8 EPE26978.1 - 1.4e-26 93.3 0.0 1.9e-25 89.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE26978.1 - 0.02 14.6 0.0 0.062 13.0 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family p450 PF00067.17 EPE26979.1 - 6.9e-62 209.4 0.0 9.1e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2953 PF11167.3 EPE26979.1 - 0.068 13.0 0.1 11 6.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) Pyr_redox_3 PF13738.1 EPE26980.1 - 1.6e-28 100.1 0.0 3.6e-28 99.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE26980.1 - 2.2e-14 52.5 0.2 5.1e-14 51.3 0.1 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPE26980.1 - 3.8e-14 52.3 0.6 9.1e-12 44.5 0.1 3.5 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EPE26980.1 - 1.7e-12 47.1 0.1 8.1e-12 44.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE26980.1 - 2.7e-06 26.5 0.0 0.00023 20.1 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPE26980.1 - 0.00012 21.9 0.1 0.024 14.4 0.0 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EPE26980.1 - 0.016 15.6 0.1 3.8 7.9 0.0 3.5 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE26980.1 - 0.12 11.4 0.2 0.92 8.5 0.1 2.3 2 0 0 2 2 2 0 Thi4 family p450 PF00067.17 EPE26982.1 - 1.2e-34 119.6 0.0 1.8e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GFO_IDH_MocA PF01408.17 EPE26982.1 - 1.7e-05 25.2 0.1 6.5e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DAGAT PF03982.8 EPE26982.1 - 0.12 11.0 0.3 0.75 8.4 0.0 2.2 3 0 0 3 3 3 0 Diacylglycerol acyltransferase DUF4351 PF14261.1 EPE26982.1 - 0.16 11.9 0.3 31 4.5 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) ATP-grasp_4 PF13535.1 EPE26983.1 - 3e-20 72.7 0.0 1.2e-17 64.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EPE26983.1 - 1.9e-06 27.3 0.0 2.4e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EPE26983.1 - 4.3e-05 22.4 0.0 0.07 11.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EPE26983.1 - 0.00013 21.9 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain TTL PF03133.10 EPE26983.1 - 0.0052 15.7 0.0 0.37 9.6 0.0 2.2 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EPE26983.1 - 0.064 12.0 0.0 0.91 8.2 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp CPSase_L_D2 PF02786.12 EPE26983.1 - 0.097 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GSH-S_ATP PF02955.11 EPE26983.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain ABC_membrane PF00664.18 EPE26984.1 - 1.6e-76 257.3 38.0 6.3e-40 137.3 8.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPE26984.1 - 5.1e-71 237.3 0.0 3.1e-35 121.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPE26984.1 - 2.3e-15 57.3 0.7 2.9e-05 24.1 0.3 4.4 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EPE26984.1 - 1.8e-13 50.2 6.4 0.00024 20.3 1.1 4.6 3 2 1 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EPE26984.1 - 9.2e-11 42.0 2.1 0.00016 21.6 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EPE26984.1 - 4.5e-09 35.4 0.2 0.0009 17.9 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EPE26984.1 - 1.1e-08 34.4 1.2 0.0032 16.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPE26984.1 - 1e-07 31.2 0.0 0.0079 15.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EPE26984.1 - 2.6e-07 31.4 0.0 0.0027 18.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPE26984.1 - 4.4e-06 26.8 0.7 0.23 11.6 0.0 4.1 3 2 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EPE26984.1 - 1.2e-05 24.6 0.0 0.076 12.0 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.7 EPE26984.1 - 1.3e-05 24.4 0.1 0.061 12.4 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin AAA_23 PF13476.1 EPE26984.1 - 2.2e-05 24.8 0.3 0.17 12.2 0.1 3.1 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.12 EPE26984.1 - 3.9e-05 23.5 0.2 0.029 14.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EPE26984.1 - 8.5e-05 22.8 0.2 0.25 11.6 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 EPE26984.1 - 0.00014 21.5 0.4 2 7.9 0.0 3.7 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 EPE26984.1 - 0.00043 20.1 3.4 0.86 9.5 0.2 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.15 EPE26984.1 - 0.00044 19.0 0.0 0.069 11.8 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit DUF815 PF05673.8 EPE26984.1 - 0.0013 17.7 0.0 0.46 9.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EPE26984.1 - 0.0013 18.4 0.0 1.5 8.5 0.0 3.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EPE26984.1 - 0.0016 18.3 0.4 1.2 8.9 0.0 4.7 6 0 0 6 6 5 1 AAA domain MMR_HSR1 PF01926.18 EPE26984.1 - 0.0031 17.4 0.0 4.7 7.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EPE26984.1 - 0.0075 15.7 0.0 4.5 6.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EPE26984.1 - 0.0098 16.3 0.0 3.9 7.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EPE26984.1 - 0.01 15.3 1.3 9 5.6 0.0 3.6 4 0 0 4 4 4 0 AAA-like domain APS_kinase PF01583.15 EPE26984.1 - 0.015 14.9 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 EPE26984.1 - 0.025 14.3 0.0 5.9 6.5 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EPE26984.1 - 0.028 13.8 0.2 2.4 7.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF3987 PF13148.1 EPE26984.1 - 0.028 12.9 0.9 2.9 6.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Dynamin_N PF00350.18 EPE26984.1 - 0.043 13.6 0.4 11 5.7 0.0 3.4 3 0 0 3 3 3 0 Dynamin family AAA_33 PF13671.1 EPE26984.1 - 0.053 13.4 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 EPE26984.1 - 0.09 12.3 0.0 9.5 5.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cache_3 PF14827.1 EPE26984.1 - 0.43 10.4 4.1 6 6.7 0.2 2.5 2 0 0 2 2 2 0 Sensory domain of two-component sensor kinase Aminotran_3 PF00202.16 EPE26985.1 - 4.8e-86 288.6 0.0 5.9e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III adh_short PF00106.20 EPE26986.1 - 3.6e-11 43.2 0.2 1.1e-10 41.6 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE26986.1 - 0.00043 20.1 0.0 0.00051 19.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE26986.1 - 0.0054 16.4 0.1 0.011 15.3 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPE26986.1 - 0.13 12.3 0.1 1.2 9.0 0.0 2.2 1 1 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 EPE26987.1 - 1.5e-63 214.9 0.0 1.8e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C14 PF00656.17 EPE26988.1 - 2e-72 243.8 0.1 2.4e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EPE26988.1 - 0.091 12.6 0.5 0.62 9.8 0.0 2.4 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Microtub_assoc PF07989.6 EPE26989.1 - 8.7e-26 89.5 3.6 8.7e-26 89.5 2.5 14.1 12 3 1 15 15 15 2 Microtubule associated PACT_coil_coil PF10495.4 EPE26989.1 - 2.2e-08 33.8 2.5 8e-08 32.0 0.1 3.3 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.4 EPE26989.1 - 0.00052 19.8 17.5 0.00052 19.8 12.1 15.4 3 2 10 14 14 14 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.1 EPE26989.1 - 0.0016 18.4 3.8 0.0016 18.4 2.7 14.7 2 1 10 13 13 13 2 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.7 EPE26989.1 - 0.77 8.8 69.1 0.62 9.1 0.8 9.3 1 1 8 11 11 11 0 Reovirus sigma C capsid protein SGT1 PF07093.6 EPE26990.1 - 4.5e-144 481.0 29.7 9e-143 476.7 20.6 2.0 1 1 0 1 1 1 1 SGT1 protein THUMP PF02926.12 EPE26992.1 - 4.5e-06 26.5 0.2 1.7e-05 24.7 0.1 1.9 1 1 0 1 1 1 1 THUMP domain NAD_binding_10 PF13460.1 EPE26993.1 - 9.6e-17 61.5 0.0 2.5e-16 60.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE26993.1 - 1.7e-11 43.8 0.0 1.3e-07 31.1 0.0 2.9 2 1 0 2 2 2 2 NmrA-like family Peripla_BP_6 PF13458.1 EPE26993.1 - 0.00054 19.4 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Epimerase PF01370.16 EPE26993.1 - 0.002 17.5 0.0 0.52 9.7 0.0 3.1 2 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family PIF1 PF05970.9 EPE26994.1 - 6.6e-43 147.0 0.1 2.3e-29 102.4 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EPE26994.1 - 6e-16 58.6 0.0 9.7e-15 54.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain Cauli_VI PF01693.11 EPE26994.1 - 4.6e-13 48.9 0.2 1.1e-12 47.7 0.1 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin AAA_22 PF13401.1 EPE26994.1 - 1.1e-08 35.2 0.0 2.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPE26994.1 - 1.4e-06 28.1 0.1 0.014 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPE26994.1 - 2e-06 27.4 0.1 5.8e-06 25.9 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 EPE26994.1 - 7.7e-05 22.7 0.3 0.0011 18.9 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EPE26994.1 - 0.00033 20.3 2.2 0.0035 17.0 0.4 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 EPE26994.1 - 0.00045 19.1 0.0 0.01 14.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DEAD PF00270.24 EPE26994.1 - 0.0011 18.5 2.1 0.24 10.8 0.1 2.5 2 1 0 3 3 3 1 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.4 EPE26994.1 - 0.0014 17.3 0.0 0.0024 16.5 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain UvrD_C_2 PF13538.1 EPE26994.1 - 0.0031 17.6 0.0 0.017 15.2 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain NACHT PF05729.7 EPE26994.1 - 0.0036 16.9 0.0 0.0068 16.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain UvrD-helicase PF00580.16 EPE26994.1 - 0.0084 15.4 1.0 0.019 14.3 0.7 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EPE26994.1 - 0.0099 14.8 0.0 0.031 13.2 0.0 1.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.1 EPE26994.1 - 0.01 14.5 0.1 0.041 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EPE26994.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 EPE26994.1 - 0.014 15.1 0.1 0.57 9.8 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 EPE26994.1 - 0.015 15.1 0.0 0.045 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EPE26994.1 - 0.04 13.1 0.1 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 EPE26994.1 - 0.044 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Herpes_Helicase PF02689.9 EPE26994.1 - 0.051 11.3 0.0 0.29 8.8 0.0 1.9 2 0 0 2 2 2 0 Helicase UPF0079 PF02367.12 EPE26994.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EPE26994.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EPE26994.1 - 0.13 12.5 0.0 0.46 10.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain cobW PF02492.14 EPE26994.1 - 0.15 11.5 0.1 0.86 9.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 EPE26994.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Mg_chelatase PF01078.16 EPE26994.1 - 0.16 11.1 0.0 0.4 9.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Fungal_trans PF04082.13 EPE26995.1 - 4.2e-18 65.1 0.1 1e-17 63.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE26995.1 - 8.9e-07 28.7 10.1 1.9e-06 27.6 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.6 EPE26995.1 - 0.0065 16.2 2.4 0.017 14.8 1.7 1.7 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) MAF_flag10 PF01973.13 EPE26996.1 - 0.037 13.5 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF115 Nrap PF03813.9 EPE26997.1 - 0 1089.0 0.0 0 1088.7 0.0 1.1 1 0 0 1 1 1 1 Nrap protein Cys_Met_Meta_PP PF01053.15 EPE26998.1 - 6.8e-34 116.7 0.0 9.6e-34 116.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPE26998.1 - 0.09 11.7 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II PCI_Csn8 PF10075.4 EPE26999.1 - 3.1e-41 140.4 0.0 4.3e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EPE26999.1 - 4.9e-24 85.0 0.1 6.8e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PDCD2_C PF04194.8 EPE27000.1 - 4.5e-54 182.4 0.1 1.6e-52 177.4 0.0 2.2 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain A2L_zn_ribbon PF08792.5 EPE27000.1 - 0.18 11.2 1.2 2.3 7.7 0.0 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain Pkinase PF00069.20 EPE27001.1 - 5.3e-65 219.1 0.0 7.6e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE27001.1 - 3.3e-47 160.7 0.0 5.2e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE27001.1 - 7.6e-10 38.2 0.0 1.1e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EPE27001.1 - 0.017 14.2 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE27001.1 - 0.021 14.5 0.4 0.29 10.8 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family SMC_N PF02463.14 EPE27002.1 - 1.7e-19 69.9 24.5 7.5e-19 67.8 16.9 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPE27002.1 - 3.6e-10 40.5 27.8 3.6e-10 40.5 19.3 5.0 2 2 0 3 3 3 1 AAA domain AAA_15 PF13175.1 EPE27002.1 - 4.2e-05 22.7 3.3 4.2e-05 22.7 2.3 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 EPE27002.1 - 0.00043 20.3 0.8 0.013 15.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EPE27002.1 - 0.00086 19.1 0.0 0.003 17.4 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EPE27002.1 - 0.0064 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KxDL PF10241.4 EPE27002.1 - 8.7 6.3 17.1 0.026 14.4 2.3 3.7 3 1 1 4 4 4 0 Uncharacterized conserved protein COQ9 PF08511.6 EPE27003.1 - 3.5e-26 90.5 0.1 5.4e-26 89.9 0.1 1.3 1 0 0 1 1 1 1 COQ9 PP2 PF14299.1 EPE27003.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Phloem protein 2 DHFR_2 PF06442.6 EPE27004.1 - 0.053 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 R67 dihydrofolate reductase Esterase_phd PF10503.4 EPE27005.1 - 3.8e-20 72.0 1.9 5.4e-20 71.5 1.3 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EPE27005.1 - 3.5e-10 39.4 0.3 4.8e-10 39.0 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE27005.1 - 2.7e-06 27.1 0.3 4e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EPE27005.1 - 0.0043 15.8 0.6 0.0066 15.2 0.4 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE27005.1 - 0.01 15.4 0.1 0.017 14.6 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EPE27005.1 - 0.14 11.5 0.5 1.1 8.6 0.4 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase HET PF06985.6 EPE27006.1 - 5.2e-31 107.6 0.1 9.8e-31 106.7 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Y2_Tnp PF04986.8 EPE27006.1 - 0.013 15.2 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 Putative transposase Adenyl_transf PF04439.7 EPE27006.1 - 0.019 14.0 0.2 0.03 13.3 0.2 1.2 1 0 0 1 1 1 0 Streptomycin adenylyltransferase Dehydratase_hem PF13816.1 EPE27008.1 - 2e-60 204.4 0.0 2.4e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase Fungal_trans PF04082.13 EPE27009.1 - 8.5e-09 34.6 0.5 1.9e-08 33.4 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27009.1 - 2.1e-07 30.6 15.0 2.4e-07 30.5 9.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.17 EPE27010.1 - 8.1e-33 113.3 0.0 1.1e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Git3 PF11710.3 EPE27011.1 - 3.3e-25 88.8 11.9 1.3e-24 86.9 8.2 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EPE27011.1 - 5e-12 45.4 0.3 5e-12 45.4 0.2 3.2 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 EPE27011.1 - 0.0012 17.7 10.8 0.0026 16.6 7.5 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Syndecan PF01034.15 EPE27011.1 - 2.4 7.8 7.5 0.12 11.9 0.4 2.1 2 0 0 2 2 2 0 Syndecan domain MFS_1 PF07690.11 EPE27012.1 - 1.7e-33 115.8 26.6 1.7e-33 115.8 18.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE27012.1 - 1.3e-06 27.2 27.5 1.5e-05 23.7 19.1 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter AMP-binding PF00501.23 EPE27013.1 - 6.5e-68 229.0 0.0 9.6e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme UPF0075 PF03702.9 EPE27013.1 - 9.3e-53 179.4 0.0 1.4e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) AMP-binding_C PF13193.1 EPE27013.1 - 1.8e-10 41.6 0.0 4.5e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PIG-S PF10510.4 EPE27014.1 - 1.3e-142 476.0 0.0 1.7e-142 475.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Diphthamide_syn PF01866.12 EPE27015.1 - 1.1e-48 166.0 0.0 7.1e-48 163.4 0.0 1.9 2 0 0 2 2 2 1 Putative diphthamide synthesis protein MARVEL PF01284.18 EPE27017.1 - 0.0032 17.2 16.8 0.0044 16.8 11.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3149 PF11346.3 EPE27017.1 - 6.5 6.4 8.9 18 5.0 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3149) HET PF06985.6 EPE27018.1 - 2e-20 73.3 6.7 1.8e-17 63.8 0.5 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3425 PF11905.3 EPE27019.1 - 2.1e-17 63.3 4.0 2.3e-16 59.9 1.6 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) Abhydrolase_6 PF12697.2 EPE27020.1 - 2.7e-16 60.1 0.6 3.6e-16 59.7 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE27020.1 - 0.00033 20.4 0.0 0.00061 19.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EPE27020.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 EPE27020.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Methyltransf_11 PF08241.7 EPE27021.1 - 2.5e-10 40.7 0.0 3.9e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE27021.1 - 4e-09 36.7 0.0 6.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE27021.1 - 2e-07 31.0 0.0 3.9e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE27021.1 - 5.4e-07 29.3 0.0 7.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE27021.1 - 1.7e-05 25.2 0.0 2.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE27021.1 - 0.00049 19.2 0.0 0.00089 18.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EPE27021.1 - 0.0013 18.4 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE27021.1 - 0.003 16.9 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EPE27021.1 - 0.0039 17.7 0.0 0.0093 16.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EPE27021.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase PLA2_B PF01735.13 EPE27025.1 - 1.7e-193 643.3 8.6 2e-193 643.0 5.9 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Prenyltrans PF00432.16 EPE27026.1 - 5.6e-40 134.5 18.9 2.6e-10 39.6 0.2 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPE27026.1 - 8.1e-24 84.2 0.0 2.7e-16 59.9 0.0 4.3 1 1 3 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPE27026.1 - 0.00011 22.2 0.0 0.0024 17.8 0.0 3.0 3 1 1 4 4 4 1 Prenyltransferase-like NTP_transferase PF00483.18 EPE27027.1 - 1.6e-48 165.1 0.0 3.6e-48 164.0 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EPE27027.1 - 2.1e-16 58.5 12.7 1.8e-09 36.6 1.3 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EPE27027.1 - 1.5e-10 41.4 0.0 2.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EPE27027.1 - 7.9e-07 28.5 1.0 7.9e-07 28.5 0.7 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Velvet PF11754.3 EPE27029.1 - 8.1e-50 169.2 1.4 8.1e-50 169.2 1.0 2.8 3 1 0 3 3 3 1 Velvet factor Lin-8 PF03353.10 EPE27029.1 - 3.6 6.7 6.3 5.7 6.1 4.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AvrE PF11725.3 EPE27029.1 - 3.6 4.4 6.1 4.7 4.0 4.2 1.0 1 0 0 1 1 1 0 Pathogenicity factor MOZ_SAS PF01853.13 EPE27031.1 - 2.9e-79 264.7 0.1 4e-79 264.2 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 EPE27031.1 - 0.00012 21.7 7.3 0.00012 21.7 5.1 2.1 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 EPE27031.1 - 0.024 14.3 0.3 0.057 13.1 0.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1825 PF08855.5 EPE27031.1 - 0.046 13.7 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) HTH_36 PF13730.1 EPE27031.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PHD_2 PF13831.1 EPE27031.1 - 2.2 7.6 5.1 0.65 9.3 1.2 2.0 2 0 0 2 2 2 0 PHD-finger DUF3129 PF11327.3 EPE27032.1 - 1.3e-54 184.7 14.1 1.3e-54 184.7 9.8 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) O-antigen_lig PF13425.1 EPE27033.1 - 0.011 15.7 0.6 0.014 15.4 0.0 1.5 2 0 0 2 2 2 0 O-antigen ligase like membrane protein MotB_plug PF13677.1 EPE27033.1 - 0.021 14.1 0.4 0.037 13.3 0.3 1.4 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB DUF4131 PF13567.1 EPE27033.1 - 0.053 12.9 0.3 0.093 12.1 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) OppC_N PF12911.2 EPE27033.1 - 3.9 6.9 6.9 18 4.7 0.2 3.1 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C BphX PF06139.7 EPE27034.1 - 0.012 15.1 0.5 0.024 14.2 0.3 1.6 1 1 0 1 1 1 0 BphX-like MENTAL PF10457.4 EPE27034.1 - 0.094 12.3 1.0 0.13 11.9 0.7 1.1 1 0 0 1 1 1 0 Cholesterol-capturing domain Tannase PF07519.6 EPE27035.1 - 3.4e-108 362.3 2.1 4.4e-108 362.0 1.5 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EPE27035.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Mannosyl_trans2 PF04188.8 EPE27038.1 - 2.1e-58 198.3 17.2 3.1e-58 197.7 11.9 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF3437 PF11919.3 EPE27040.1 - 1.2e-32 111.4 0.0 3.2e-32 110.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EPE27040.1 - 0.0038 17.1 2.2 9.5 6.6 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat HET PF06985.6 EPE27041.1 - 1.9e-34 118.8 0.0 2.8e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TMEM52 PF14979.1 EPE27041.1 - 0.086 12.7 0.3 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Transmembrane 52 Herpes_UL95 PF03038.9 EPE27042.1 - 0.15 10.9 0.4 0.19 10.5 0.3 1.1 1 0 0 1 1 1 0 UL95 family IBR PF01485.16 EPE27043.1 - 1.3e-09 37.7 26.5 4.5e-07 29.6 3.0 4.8 4 1 1 5 5 5 2 IBR domain DUF982 PF06169.7 EPE27043.1 - 0.00072 19.2 0.1 0.0015 18.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF982) Pribosyltran PF00156.22 EPE27044.1 - 1.7e-16 60.0 0.0 3.5e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.18 EPE27044.1 - 7.6e-14 51.3 3.9 1.8e-13 50.1 2.7 1.7 1 0 0 1 1 1 1 FAD binding domain P-mevalo_kinase PF04275.9 EPE27044.1 - 6.2e-10 38.8 0.0 1.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Phosphomevalonate kinase BBE PF08031.7 EPE27044.1 - 0.0002 21.1 0.0 0.00063 19.5 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like UPRTase PF14681.1 EPE27044.1 - 0.00086 18.5 0.0 0.0019 17.4 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Methyltransf_23 PF13489.1 EPE27044.1 - 0.0019 17.9 0.0 0.017 14.8 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain TPR_12 PF13424.1 EPE27045.1 - 6e-20 70.9 18.6 9.4e-07 28.6 0.1 6.6 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 EPE27045.1 - 1.7e-12 46.8 18.0 4.3e-06 26.4 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.17 EPE27045.1 - 0.00025 20.0 0.0 0.19 10.5 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain TPR_1 PF00515.23 EPE27045.1 - 0.00025 20.5 2.8 0.44 10.2 0.3 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPE27045.1 - 0.00046 19.7 5.8 1.6 8.4 0.0 4.7 5 0 0 5 5 5 1 TPR repeat TPR_9 PF13371.1 EPE27045.1 - 0.00058 19.6 1.2 0.53 10.1 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat Arch_ATPase PF01637.13 EPE27045.1 - 0.00062 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase TPR_2 PF07719.12 EPE27045.1 - 0.00064 19.4 9.9 0.064 13.2 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE27045.1 - 0.0022 18.6 3.0 9.2 7.0 0.1 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EPE27045.1 - 0.0072 16.6 10.0 1.1 9.9 0.4 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPE27045.1 - 0.078 12.7 1.7 7.9 6.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPE27045.1 - 0.43 11.3 5.5 22 6.0 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat p450 PF00067.17 EPE27046.1 - 1.1e-31 109.8 0.0 1.3e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Na_Ca_ex PF01699.19 EPE27047.1 - 5.3e-46 155.6 39.5 3.7e-26 91.4 8.7 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Stn1 PF10451.4 EPE27048.1 - 1.6e-12 46.8 0.7 2e-10 39.9 0.5 2.1 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 EPE27048.1 - 0.00073 19.3 0.2 0.075 12.9 0.1 2.5 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DnaJ PF00226.26 EPE27049.1 - 2.2e-21 75.3 4.8 2.2e-21 75.3 3.3 2.1 2 0 0 2 2 2 1 DnaJ domain Porphobil_deam PF01379.15 EPE27050.1 - 4.4e-83 277.4 0.1 6.9e-83 276.7 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EPE27050.1 - 6e-18 64.7 0.1 1.3e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GCV_H PF01597.14 EPE27051.1 - 7.7e-34 115.9 1.1 9.7e-34 115.6 0.8 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Ras PF00071.17 EPE27052.1 - 2.7e-31 108.1 0.1 3.7e-31 107.7 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE27052.1 - 2.3e-20 73.2 0.1 7.9e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPE27052.1 - 1e-06 28.0 0.1 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPE27052.1 - 1.4e-05 24.3 0.2 1.9e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF3602 PF12223.3 EPE27052.1 - 0.0025 18.1 4.0 0.0025 18.1 2.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3602) G-alpha PF00503.15 EPE27052.1 - 0.04 12.6 3.3 0.22 10.1 0.0 2.6 1 1 1 3 3 3 0 G-protein alpha subunit DLIC PF05783.6 EPE27052.1 - 0.12 10.9 3.8 3.9 6.0 0.0 2.4 2 1 1 3 3 3 0 Dynein light intermediate chain (DLIC) DUF1590 PF07629.6 EPE27052.1 - 0.21 11.2 6.4 0.44 10.1 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) PLAC8 PF04749.12 EPE27053.1 - 1.3e-16 61.0 5.8 2.6e-16 60.1 4.0 1.5 1 0 0 1 1 1 1 PLAC8 family Ycf1 PF05758.7 EPE27054.1 - 1.9 6.0 11.2 2.1 5.9 7.7 1.1 1 0 0 1 1 1 0 Ycf1 TIP120 PF08623.5 EPE27055.1 - 4.6e-64 215.0 2.5 4.8e-63 211.7 0.1 3.6 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EPE27055.1 - 7.5e-18 64.6 20.2 0.033 14.4 1.9 9.2 9 1 1 10 10 10 5 HEAT repeats HEAT PF02985.17 EPE27055.1 - 1.4e-16 59.0 8.4 0.058 13.5 0.0 11.4 12 0 0 12 12 12 4 HEAT repeat DUF2435 PF10363.4 EPE27055.1 - 9.1e-08 31.9 5.9 0.083 12.7 0.0 6.3 6 1 1 7 7 7 2 Protein of unknown function (DUF2435) Cnd1 PF12717.2 EPE27055.1 - 9.6e-06 25.5 10.1 0.17 11.7 0.0 5.8 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EPE27055.1 - 0.00034 20.0 1.5 0.32 10.3 0.0 4.3 4 1 1 5 5 5 1 CLASP N terminal HEAT_EZ PF13513.1 EPE27055.1 - 0.00048 20.5 23.4 1.6 9.3 0.3 11.2 12 3 1 13 13 13 1 HEAT-like repeat Proteasom_PSMB PF10508.4 EPE27055.1 - 0.0066 14.7 4.7 0.037 12.2 0.2 3.5 3 2 0 3 3 3 1 Proteasome non-ATPase 26S subunit DUF2457 PF10446.4 EPE27055.1 - 1.3 7.6 8.7 2 7.0 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GFA PF04828.9 EPE27056.1 - 8.1e-08 32.1 0.0 1.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme zf-CGNR PF11706.3 EPE27056.1 - 0.0077 15.7 0.3 0.019 14.4 0.2 1.6 1 0 0 1 1 1 1 CGNR zinc finger Nudix_N_2 PF14803.1 EPE27056.1 - 0.21 11.2 4.6 0.86 9.3 0.1 3.0 3 0 0 3 3 3 0 Nudix N-terminal Peptidase_M28 PF04389.12 EPE27057.1 - 1.2e-36 126.1 0.0 1.7e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EPE27057.1 - 1.1e-13 50.7 0.6 3.1e-13 49.2 0.3 1.8 2 0 0 2 2 2 1 PA domain GMC_oxred_N PF00732.14 EPE27059.1 - 4.2e-78 262.5 0.0 5.9e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE27059.1 - 9.3e-36 123.2 0.0 2e-35 122.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPE27059.1 - 1.7e-06 27.1 0.2 1.1e-05 24.5 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE27059.1 - 0.00014 20.8 0.1 0.11 11.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EPE27059.1 - 0.0068 15.3 0.1 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EPE27059.1 - 0.064 12.3 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Dynamin_N PF00350.18 EPE27060.1 - 1.1e-16 61.0 0.5 2.2e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EPE27060.1 - 4.5e-09 36.2 0.0 1.6e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPE27060.1 - 1.6e-07 30.9 0.1 8.8e-07 28.5 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2205 PF10224.4 EPE27060.1 - 0.0029 17.1 2.6 0.0031 17.0 0.2 2.3 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) PMEI PF04043.10 EPE27060.1 - 0.0082 16.0 0.9 0.019 14.8 0.6 1.6 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor IIGP PF05049.8 EPE27060.1 - 0.031 13.0 0.0 0.067 11.9 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 EPE27060.1 - 0.052 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EPE27060.1 - 0.069 13.4 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Snf7 PF03357.16 EPE27061.1 - 1.9e-38 131.4 17.0 2.6e-38 131.0 11.8 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EPE27061.1 - 0.0083 15.5 3.7 0.015 14.7 2.6 1.4 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.3 EPE27061.1 - 0.034 14.1 16.3 3.1 7.8 8.0 2.2 1 1 1 2 2 2 0 YlqD protein V_ATPase_I PF01496.14 EPE27061.1 - 0.064 11.1 2.5 0.079 10.8 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATP-synt_B PF00430.13 EPE27061.1 - 4 7.2 12.3 11 5.8 0.1 2.5 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) Laminin_II PF06009.7 EPE27061.1 - 9 6.0 8.9 2.7 7.7 0.2 2.6 1 1 1 2 2 2 0 Laminin Domain II PP2C PF00481.16 EPE27062.1 - 8.8e-64 215.3 1.2 1.1e-51 175.6 0.4 3.2 2 1 1 3 3 3 3 Protein phosphatase 2C Herpes_LMP2 PF07415.6 EPE27062.1 - 0.35 9.4 1.9 0.57 8.7 1.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Glyco_hydro_81 PF03639.8 EPE27063.1 - 1e-208 694.7 0.1 1.2e-208 694.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Utp14 PF04615.8 EPE27064.1 - 1.2e-206 688.3 60.6 1.2e-206 688.3 42.0 2.1 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.4 EPE27065.1 - 6.2e-18 64.4 0.3 8.7e-18 63.9 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Peptidase_M54 PF07998.6 EPE27066.1 - 6.8e-07 29.2 0.1 3.1e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M54 Reprolysin_2 PF13574.1 EPE27066.1 - 0.085 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Endonuclease_1 PF04231.8 EPE27066.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Endonuclease I Metallopep PF12044.3 EPE27066.1 - 0.14 10.5 0.1 0.27 9.6 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_4 PF13583.1 EPE27066.1 - 0.16 11.5 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Ribonuclease_T2 PF00445.13 EPE27067.1 - 9.1e-44 149.3 0.2 1.7e-43 148.4 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family DUF1792 PF08759.6 EPE27067.1 - 0.0039 16.8 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1792) Aldolase_II PF00596.16 EPE27068.1 - 4.9e-27 94.7 0.4 6.3e-27 94.3 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MGC-24 PF05283.6 EPE27069.1 - 8.4 6.1 6.7 1.1 9.0 1.6 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Abhydrolase_3 PF07859.8 EPE27070.1 - 8.9e-34 116.9 0.0 1.3e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE27070.1 - 3.3e-07 30.4 0.0 5.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE27070.1 - 1.6e-06 27.9 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE27070.1 - 0.002 17.6 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 EPE27070.1 - 0.0037 16.5 0.0 0.0057 15.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family COesterase PF00135.23 EPE27070.1 - 0.0039 15.9 0.0 0.014 14.1 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family AXE1 PF05448.7 EPE27070.1 - 0.011 14.2 0.0 0.017 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2424 PF10340.4 EPE27070.1 - 0.012 14.2 0.0 0.054 12.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2424) BAAT_C PF08840.6 EPE27070.1 - 0.025 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 EPE27070.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.16 EPE27070.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans PF04082.13 EPE27071.1 - 9.8e-21 73.7 0.0 1.2e-19 70.1 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27071.1 - 9.2e-09 35.0 8.0 1.6e-08 34.2 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.19 EPE27072.1 - 3.1e-31 108.9 1.3 1.5e-30 106.7 0.9 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EPE27072.1 - 0.0084 13.9 2.9 1.1 6.8 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 DUF1939 PF09154.5 EPE27072.1 - 0.022 14.6 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) HRXXH PF13933.1 EPE27074.1 - 3.1e-12 46.4 0.7 6.8e-12 45.3 0.5 1.5 1 1 0 1 1 1 1 Putative peptidase family DUF1338 PF07063.8 EPE27074.1 - 0.074 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) Fungal_trans_2 PF11951.3 EPE27075.1 - 1.6e-09 36.8 3.0 2.5e-09 36.2 2.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27075.1 - 7.4e-09 35.3 8.7 1.9e-08 34.0 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 EPE27076.1 - 1.5e-54 185.2 5.9 1.8e-54 184.9 4.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Cation_ATPase_C PF00689.16 EPE27076.1 - 0.035 13.6 7.1 0.63 9.5 0.2 2.5 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF3722 PF12519.3 EPE27077.1 - 1.2e-93 313.1 0.0 1.5e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EPE27077.1 - 2e-07 30.5 0.0 0.032 13.5 0.0 3.3 4 0 0 4 4 4 2 Eukaryotic porin Ribosomal_L10 PF00466.15 EPE27078.1 - 4.4e-20 71.4 0.0 6.8e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.3 EPE27079.1 - 2.3e-31 107.9 3.6 2.3e-31 107.9 2.5 1.6 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EPE27079.1 - 6.5e-17 60.9 0.2 3.3e-16 58.6 0.2 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE27079.1 - 3.4e-13 49.3 0.0 5.6e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE27079.1 - 6.8e-09 35.4 0.2 2.4e-08 33.7 0.2 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3035 PF11233.3 EPE27079.1 - 0.14 12.1 0.3 0.3 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) L51_S25_CI-B8 PF05047.11 EPE27080.1 - 7.6e-12 44.7 0.0 1.1e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain E1-E2_ATPase PF00122.15 EPE27081.1 - 0.018 14.0 0.2 0.021 13.8 0.1 1.1 1 0 0 1 1 1 0 E1-E2 ATPase EphA2_TM PF14575.1 EPE27081.1 - 0.076 13.4 0.0 0.094 13.1 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gly-zipper_YMGG PF13441.1 EPE27082.1 - 0.033 13.7 1.8 0.05 13.1 1.2 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 EPE27082.1 - 0.037 14.1 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Podoplanin PF05808.6 EPE27082.1 - 0.059 12.9 0.2 0.58 9.6 0.0 2.0 2 0 0 2 2 2 0 Podoplanin Rick_17kDa_Anti PF05433.10 EPE27082.1 - 0.081 12.6 2.9 0.14 11.7 2.0 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EPE27082.1 - 0.21 11.2 2.6 0.36 10.4 1.8 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1469 PF07332.6 EPE27083.1 - 0.0064 16.2 0.2 0.01 15.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) DUF485 PF04341.7 EPE27083.1 - 0.046 13.4 0.1 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DivIC PF04977.10 EPE27083.1 - 0.058 12.8 0.1 0.083 12.3 0.1 1.1 1 0 0 1 1 1 0 Septum formation initiator NTase_sub_bind PF08780.6 EPE27083.1 - 0.071 12.8 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like Innexin PF00876.13 EPE27084.1 - 0.046 12.8 0.1 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 Innexin DUF3328 PF11807.3 EPE27084.1 - 0.12 12.0 0.2 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) BatD PF13584.1 EPE27084.1 - 0.12 10.9 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance FA_desaturase PF00487.19 EPE27085.1 - 0.085 12.2 1.4 0.13 11.7 1.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase TMEM154 PF15102.1 EPE27085.1 - 0.98 9.1 5.7 0.11 12.1 0.5 2.2 2 1 0 2 2 2 0 TMEM154 protein family DUF1295 PF06966.7 EPE27086.1 - 2.1e-43 148.3 0.1 1.4e-41 142.3 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EPE27086.1 - 0.0016 18.5 0.6 0.027 14.5 0.0 2.8 2 1 1 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 EPE27086.1 - 0.0017 18.5 0.1 0.04 14.1 0.0 2.6 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 EPE27086.1 - 0.0052 16.5 0.0 0.41 10.3 0.0 2.3 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase dCMP_cyt_deam_1 PF00383.17 EPE27087.1 - 3.2e-13 49.2 0.0 4.4e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region WD40 PF00400.27 EPE27088.1 - 9.4e-35 117.2 4.1 4.2e-10 39.1 0.0 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat Nudix_N_2 PF14803.1 EPE27088.1 - 0.032 13.9 2.0 0.093 12.4 1.4 1.8 1 0 0 1 1 1 0 Nudix N-terminal DUF382 PF04037.8 EPE27089.1 - 9.6e-62 206.5 0.6 9.6e-62 206.5 0.4 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.11 EPE27089.1 - 4.6e-21 73.9 6.5 1.1e-20 72.7 4.5 1.7 1 0 0 1 1 1 1 PSP DUF241 PF03087.9 EPE27090.1 - 0.0042 16.6 0.1 0.0055 16.2 0.1 1.2 1 0 0 1 1 1 1 Arabidopsis protein of unknown function DUF2956 PF11169.3 EPE27090.1 - 0.015 15.2 3.0 0.028 14.3 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) APG6 PF04111.7 EPE27090.1 - 0.23 10.4 8.0 0.4 9.6 3.7 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EPE27090.1 - 0.29 10.7 4.7 0.45 10.0 3.3 1.2 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EPE27090.1 - 1.7 8.2 8.9 3.5 7.1 6.2 1.5 1 0 0 1 1 1 0 Septum formation initiator WASH-7_C PF14746.1 EPE27090.1 - 2.7 7.5 4.9 4.4 6.8 3.4 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal zf-CCHH PF10283.4 EPE27091.1 - 1.7 8.5 7.1 51 3.8 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif Chromo PF00385.19 EPE27092.1 - 3.4e-08 33.0 0.4 6.9e-08 32.0 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCCH PF00642.19 EPE27092.1 - 0.026 14.2 0.5 0.026 14.2 0.3 4.2 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ras PF00071.17 EPE27093.1 - 1.6e-63 212.9 0.2 1.8e-63 212.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE27093.1 - 6.2e-22 78.3 0.1 8.7e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE27093.1 - 2.5e-13 49.6 0.1 3.3e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EPE27093.1 - 3.4e-08 33.4 0.1 5.4e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPE27093.1 - 4e-05 23.1 0.1 0.00014 21.4 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPE27093.1 - 6.1e-05 22.2 0.1 9.7e-05 21.6 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EPE27093.1 - 0.00011 22.4 0.1 0.00031 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPE27093.1 - 0.0011 18.8 0.1 0.0031 17.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EPE27093.1 - 0.0022 17.1 0.1 0.0028 16.7 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EPE27093.1 - 0.0029 16.8 0.1 0.0066 15.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 EPE27093.1 - 0.0069 16.2 0.1 0.085 12.8 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 EPE27093.1 - 0.01 15.0 0.0 0.014 14.5 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EPE27093.1 - 0.018 15.0 0.4 0.047 13.6 0.2 1.8 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EPE27093.1 - 0.022 15.0 0.1 0.035 14.3 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EPE27093.1 - 0.024 14.1 0.1 0.04 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EPE27093.1 - 0.085 12.1 0.1 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EPE27093.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EPE27093.1 - 0.12 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CENP-K PF11802.3 EPE27094.1 - 0.17 11.0 2.6 0.26 10.5 1.8 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Brix PF04427.13 EPE27095.1 - 6.6e-40 136.8 0.1 8.3e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain ATP-synt_ab PF00006.20 EPE27096.1 - 1e-69 234.3 0.0 1.7e-69 233.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPE27096.1 - 1.9e-27 95.9 0.0 5.9e-27 94.3 0.0 1.9 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPE27096.1 - 1.3e-15 57.3 2.8 3.3e-15 56.0 2.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EPE27096.1 - 0.0038 17.1 1.0 0.0086 15.9 0.7 1.6 1 0 0 1 1 1 1 HAS barrel domain Arch_ATPase PF01637.13 EPE27096.1 - 0.034 13.8 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 EPE27096.1 - 0.035 13.5 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Hist_deacetyl PF00850.14 EPE27097.1 - 1.2e-91 307.2 0.0 1.7e-91 306.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EPE27097.1 - 5.4e-34 117.1 0.2 9.1e-34 116.4 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain UBN2_3 PF14244.1 EPE27097.1 - 0.054 13.0 0.2 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Gp_dh_C PF02800.15 EPE27098.1 - 1.6e-74 248.5 0.1 2.4e-74 247.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EPE27098.1 - 3.3e-59 199.1 0.1 5.7e-59 198.4 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EPE27098.1 - 0.008 16.0 0.1 0.026 14.4 0.1 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus APH PF01636.18 EPE27100.1 - 6e-10 39.2 0.0 1.4e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE27100.1 - 8.8e-05 22.1 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1289 PF06945.8 EPE27100.1 - 0.061 12.7 2.2 13 5.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) EcKinase PF02958.15 EPE27100.1 - 0.084 12.0 0.0 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase COX4 PF02936.9 EPE27101.1 - 1.9e-48 163.8 0.2 2.3e-48 163.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.6 EPE27101.1 - 0.06 13.4 0.3 0.32 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DUF3333 PF11812.3 EPE27101.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) AAA_2 PF07724.9 EPE27102.1 - 1.3e-37 129.3 0.0 2.7e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EPE27102.1 - 1.2e-14 54.6 0.1 3.1e-14 53.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPE27102.1 - 2.6e-07 30.4 0.0 5.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPE27102.1 - 3.5e-06 27.1 0.1 1.2e-05 25.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain ClpB_D2-small PF10431.4 EPE27102.1 - 1.3e-05 24.9 0.1 0.035 14.0 0.0 2.5 2 0 0 2 2 2 2 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EPE27102.1 - 6.4e-05 23.0 1.1 0.00086 19.3 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain MCM PF00493.18 EPE27102.1 - 8.3e-05 21.5 0.4 0.00015 20.6 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family AAA_14 PF13173.1 EPE27102.1 - 0.00011 22.1 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EPE27102.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 EPE27102.1 - 0.0033 16.9 0.0 0.015 14.7 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 EPE27102.1 - 0.009 16.8 0.4 0.028 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 EPE27102.1 - 0.018 13.7 0.2 0.027 13.1 0.2 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.1 EPE27102.1 - 0.03 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPE27102.1 - 0.036 14.3 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 EPE27102.1 - 0.037 13.1 0.3 0.3 10.2 0.0 2.3 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 EPE27102.1 - 0.038 13.4 0.1 0.08 12.4 0.1 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EPE27102.1 - 0.046 13.3 1.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EPE27102.1 - 0.072 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPE27102.1 - 0.073 12.6 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Alpha-amylase_C PF02806.13 EPE27103.1 - 1.1e-25 89.6 0.0 2.9e-25 88.2 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EPE27103.1 - 9.5e-19 67.9 0.4 3.8e-15 56.0 0.3 2.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 EPE27103.1 - 1.6e-17 63.3 0.1 5.3e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) ATP-synt_ab PF00006.20 EPE27104.1 - 1.6e-61 207.5 0.0 2.3e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPE27104.1 - 1.4e-25 89.9 0.5 2.5e-25 89.1 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPE27104.1 - 4.3e-23 81.3 1.3 1.1e-22 79.9 0.4 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 EPE27104.1 - 0.0042 16.5 0.1 0.037 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EPE27104.1 - 0.0061 16.2 0.0 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 EPE27104.1 - 0.0088 16.2 0.1 0.64 10.2 0.0 3.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EPE27104.1 - 0.012 14.8 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EPE27104.1 - 0.012 15.3 0.2 1.1 8.9 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EPE27104.1 - 0.016 15.1 0.4 0.24 11.3 0.3 2.4 1 1 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 EPE27104.1 - 0.017 14.2 0.3 0.035 13.2 0.1 1.6 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 EPE27104.1 - 0.025 14.2 0.1 0.063 12.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EPE27104.1 - 0.062 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EPE27104.1 - 0.096 11.5 0.9 0.59 8.9 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.1 EPE27104.1 - 0.1 12.7 0.1 0.39 10.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain GAF PF01590.21 EPE27106.1 - 0.00076 19.6 0.0 0.0026 17.9 0.0 1.9 1 0 0 1 1 1 1 GAF domain Glyco_transf_17 PF04724.8 EPE27107.1 - 2e-49 168.5 1.3 3.2e-49 167.8 0.9 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 17 DUF4131 PF13567.1 EPE27107.1 - 0.059 12.7 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SpoIIE PF07228.7 EPE27108.1 - 5.9e-11 42.4 0.0 3e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EPE27108.1 - 6.8e-09 35.4 0.0 0.00014 21.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EPE27108.1 - 1.1e-08 34.6 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C HSCB_C PF07743.8 EPE27109.1 - 8.1e-15 55.0 7.4 1.6e-14 54.1 4.6 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EPE27109.1 - 3.3e-10 39.5 0.0 7.7e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain adh_short PF00106.20 EPE27110.1 - 1.4e-17 64.1 0.0 3e-17 63.0 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE27110.1 - 9.3e-15 55.0 0.0 1.5e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE27110.1 - 8.2e-08 32.1 0.0 5.8e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EPE27110.1 - 0.003 17.5 0.0 1.3 8.9 0.0 2.6 2 1 1 3 3 3 2 NADH(P)-binding dCMP_cyt_deam_1 PF00383.17 EPE27111.1 - 3.1e-15 55.6 0.1 3.9e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EPE27111.1 - 4.5e-08 33.1 1.7 2.1e-07 30.9 0.1 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EPE27111.1 - 0.0088 15.4 0.7 0.67 9.3 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases RRM_6 PF14259.1 EPE27112.1 - 1.9e-08 34.1 0.0 4.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE27112.1 - 2.4e-08 33.4 0.0 6.7e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE27112.1 - 0.21 11.4 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HET PF06985.6 EPE27113.1 - 1.3e-24 86.9 0.3 1.3e-24 86.9 0.2 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Amidoligase_2 PF12224.3 EPE27114.1 - 8.4e-19 68.1 0.0 1.1e-17 64.5 0.0 2.2 1 1 0 1 1 1 1 Putative amidoligase enzyme SH3BGR PF04908.10 EPE27115.1 - 7.4e-05 22.6 0.0 0.00023 21.0 0.0 1.9 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein DUF4265 PF14085.1 EPE27115.1 - 0.041 13.6 0.0 1.6 8.4 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4265) DUF4661 PF15576.1 EPE27115.1 - 2.6 7.6 12.8 0.044 13.4 1.9 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4661) TPP_enzyme_N PF02776.13 EPE27116.1 - 1.6e-42 144.9 0.1 3.4e-42 143.8 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPE27116.1 - 4.8e-31 107.3 0.1 1.1e-30 106.1 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EPE27116.1 - 1.5e-21 76.5 0.0 1.7e-20 73.1 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EPE27116.1 - 5.4e-05 22.8 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit B12-binding PF02310.14 EPE27116.1 - 0.21 11.4 3.3 0.17 11.7 0.3 2.3 3 0 0 3 3 3 0 B12 binding domain SDA1 PF05285.7 EPE27119.1 - 0.057 12.6 40.0 0.0083 15.4 21.5 2.1 2 0 0 2 2 2 0 SDA1 CDC27 PF09507.5 EPE27119.1 - 4.1 6.5 37.1 2.8 7.0 0.6 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SHS2_Rpb7-N PF03876.12 EPE27120.1 - 2.8e-16 59.4 0.0 4.7e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EPE27120.1 - 1.4e-11 44.3 0.0 2.4e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.6 EPE27121.1 - 1.1e-25 89.2 1.0 1.7e-25 88.7 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF2681 PF10883.3 EPE27121.1 - 0.079 13.1 0.4 0.15 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF1770 PF08589.5 EPE27124.1 - 1.8 9.2 11.9 1.8 9.2 0.3 3.5 3 1 0 3 3 3 0 Fungal protein of unknown function (DUF1770) FAD_binding_4 PF01565.18 EPE27125.1 - 2.5e-19 69.1 1.2 5.7e-19 67.9 0.8 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE27125.1 - 0.03 14.2 0.1 0.074 12.9 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Peptidase_S28 PF05577.7 EPE27126.1 - 1.4e-52 178.7 0.0 3.3e-52 177.5 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 ORC5_C PF14630.1 EPE27128.1 - 5.6e-72 242.4 0.0 7.3e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EPE27128.1 - 1.3e-09 38.2 0.2 4.1e-09 36.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EPE27128.1 - 0.039 14.1 0.0 0.083 13.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EPE27128.1 - 0.045 12.6 0.0 0.086 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EPE27128.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EPE27128.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase INTS2 PF14750.1 EPE27128.1 - 0.23 8.9 0.1 0.33 8.4 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 Fungal_trans_2 PF11951.3 EPE27129.1 - 6.3e-09 34.9 0.2 9.3e-09 34.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27129.1 - 2.4e-07 30.5 9.3 4.1e-07 29.8 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.6 EPE27130.1 - 0.0022 17.7 6.4 0.0054 16.5 4.5 1.6 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Herpes_gE PF02480.11 EPE27130.1 - 0.0032 15.7 0.3 0.0046 15.2 0.2 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E FixQ PF05545.6 EPE27130.1 - 0.024 14.2 0.2 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Lamp PF01299.12 EPE27130.1 - 0.18 10.9 0.0 0.18 10.9 0.0 2.7 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Sporozoite_P67 PF05642.6 EPE27130.1 - 0.31 8.8 7.5 0.57 7.9 5.2 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VTC PF09359.5 EPE27131.1 - 5.1e-92 307.8 0.7 5.1e-92 307.8 0.5 1.8 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EPE27131.1 - 6.3e-16 58.9 19.5 5.4e-08 32.9 1.0 4.5 3 1 1 4 4 4 2 SPX domain DUF202 PF02656.10 EPE27131.1 - 2.9e-11 43.4 0.9 6.4e-11 42.3 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Cob_adeno_trans PF01923.13 EPE27131.1 - 0.005 16.6 0.7 3.1 7.5 0.0 2.8 2 1 0 2 2 2 2 Cobalamin adenosyltransferase DUF2628 PF10947.3 EPE27131.1 - 2.6 7.8 4.4 0.59 9.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Arm PF00514.18 EPE27132.1 - 4.4e-09 35.8 18.2 0.00088 19.0 0.0 8.3 9 1 1 10 10 10 3 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EPE27132.1 - 3.8e-05 23.3 6.8 1.3 9.2 0.1 7.0 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EPE27132.1 - 0.00091 19.6 10.9 0.022 15.2 0.0 7.2 9 0 0 9 9 9 1 HEAT-like repeat HEAT_2 PF13646.1 EPE27132.1 - 0.0038 17.4 8.1 1.2 9.4 0.1 5.4 6 0 0 6 6 6 1 HEAT repeats Cyclin PF08613.6 EPE27133.1 - 5.4e-30 104.7 0.0 9.6e-30 103.9 0.0 1.4 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EPE27133.1 - 5.4e-05 22.7 0.0 8.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SNARE PF05739.14 EPE27136.1 - 2.5e-08 33.5 1.3 3.4e-08 33.0 0.9 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EPE27136.1 - 0.0035 16.8 0.0 0.0039 16.6 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Apc15p PF05841.6 EPE27137.1 - 2.1e-18 67.2 6.6 2.1e-18 67.2 4.5 2.3 2 1 0 2 2 2 1 Apc15p protein Spidroin_MaSp PF11260.3 EPE27137.1 - 0.035 14.1 0.8 0.066 13.2 0.5 1.3 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 GATase_2 PF00310.16 EPE27138.1 - 1.8e-140 467.7 0.0 2.4e-140 467.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.12 EPE27138.1 - 7.9e-120 400.1 0.2 1.2e-85 287.6 0.0 2.3 1 1 1 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.9 EPE27138.1 - 1.3e-116 388.9 0.0 2.4e-116 388.0 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EPE27138.1 - 1.4e-66 223.4 2.4 2.6e-66 222.4 1.7 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EPE27138.1 - 6.3e-23 80.5 0.1 1.5e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EPE27138.1 - 9.3e-16 58.3 0.1 2.5e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE27138.1 - 1.6e-10 41.4 0.2 0.00045 20.3 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE27138.1 - 4e-09 36.7 0.0 1.1e-05 25.7 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE27138.1 - 5.7e-09 35.8 0.0 2.2e-08 33.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EPE27138.1 - 5.2e-06 25.1 0.1 1.2e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EPE27138.1 - 8.7e-06 24.8 0.3 6.1e-05 22.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EPE27138.1 - 1.7e-05 24.1 0.0 3.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EPE27138.1 - 4.4e-05 22.5 0.1 0.00015 20.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EPE27138.1 - 0.00086 18.4 0.3 0.0051 15.9 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EPE27138.1 - 0.00097 18.3 0.1 0.0022 17.1 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EPE27138.1 - 0.0015 18.2 0.0 0.0037 17.0 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 EPE27138.1 - 0.0019 18.4 3.8 0.33 11.2 0.1 3.2 3 0 0 3 3 2 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 EPE27138.1 - 0.0031 17.3 0.8 1.3 8.8 0.1 2.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_3 PF01494.14 EPE27138.1 - 0.0034 16.4 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EPE27138.1 - 0.0046 16.5 0.1 0.074 12.6 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.14 EPE27138.1 - 0.0049 15.1 0.2 1.9 6.5 0.0 2.2 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like DJ-1_PfpI PF01965.19 EPE27138.1 - 0.012 15.0 0.9 0.6 9.5 0.1 2.4 1 1 1 2 2 2 0 DJ-1/PfpI family ApbA PF02558.11 EPE27138.1 - 0.032 13.6 0.1 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EPE27138.1 - 0.048 13.5 0.2 0.17 11.6 0.0 2.0 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.17 EPE27138.1 - 0.049 12.5 0.1 0.049 12.5 0.0 2.1 3 0 0 3 3 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EPE27138.1 - 0.055 12.3 0.1 1.1 8.1 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EPE27138.1 - 0.1 12.7 0.2 9.5 6.3 0.0 2.7 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EPE27138.1 - 0.12 11.4 0.2 0.43 9.6 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EPE27138.1 - 0.44 10.1 2.8 0.18 11.4 0.1 1.7 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aldedh PF00171.17 EPE27139.1 - 2.3e-138 461.4 0.0 2.8e-138 461.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPE27139.1 - 0.0039 15.9 0.0 0.011 14.4 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Epimerase PF01370.16 EPE27140.1 - 6.3e-17 61.8 0.0 1.1e-16 60.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPE27140.1 - 3.1e-11 42.6 0.0 3.2e-10 39.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EPE27140.1 - 1.7e-10 40.0 0.0 2.9e-10 39.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPE27140.1 - 1.2e-07 31.9 0.2 2.3e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE27140.1 - 0.0036 16.5 0.3 0.047 12.9 0.1 2.3 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EPE27140.1 - 0.0076 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DUF3425 PF11905.3 EPE27141.1 - 1.3e-35 122.2 2.8 2.3e-35 121.4 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EPE27141.1 - 0.0053 16.6 12.9 0.014 15.3 8.4 2.1 1 1 1 2 2 2 1 bZIP transcription factor DUF2937 PF11157.3 EPE27141.1 - 0.13 11.5 1.5 0.23 10.7 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Nic96 PF04097.9 EPE27142.1 - 3.1e-180 600.3 0.0 5.6e-180 599.4 0.0 1.4 1 1 1 2 2 2 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 EPE27142.1 - 0.0031 17.7 40.0 0.0031 17.7 27.7 3.3 2 1 1 3 3 3 1 Nucleoporin FG repeat region Y_phosphatase PF00102.22 EPE27143.1 - 2e-61 207.3 0.5 9.8e-60 201.8 0.4 2.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EPE27143.1 - 1.1e-09 38.5 0.0 8.3e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 EPE27143.1 - 0.0063 16.0 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EPE27143.1 - 0.01 16.0 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family MFS_1 PF07690.11 EPE27144.1 - 1.6e-39 135.6 25.2 4e-38 131.0 16.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 EPE27144.1 - 0.25 10.8 0.1 0.25 10.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Na_Ca_ex PF01699.19 EPE27146.1 - 3.5e-31 107.6 26.9 4.3e-18 65.2 8.0 3.4 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EPE27146.1 - 7.3e-14 51.9 13.4 7.3e-14 51.9 9.3 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF307) AAA PF00004.24 EPE27147.1 - 5.2e-44 149.6 0.0 8.5e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPE27147.1 - 3.2e-08 33.4 0.0 7.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPE27147.1 - 1.2e-07 31.8 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPE27147.1 - 3.1e-06 27.2 0.0 6.8e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE27147.1 - 5.2e-06 26.6 0.1 0.00025 21.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE27147.1 - 6.9e-05 23.6 0.0 0.00015 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPE27147.1 - 7.6e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EPE27147.1 - 0.00013 21.6 0.1 0.00029 20.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EPE27147.1 - 0.00041 19.8 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EPE27147.1 - 0.00088 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EPE27147.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPE27147.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPE27147.1 - 0.0024 16.9 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EPE27147.1 - 0.0025 17.4 0.0 0.0074 15.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EPE27147.1 - 0.0039 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EPE27147.1 - 0.0067 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EPE27147.1 - 0.0067 15.5 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 EPE27147.1 - 0.0078 16.5 0.0 0.028 14.7 0.0 2.1 3 0 0 3 3 1 1 AAA domain AAA_25 PF13481.1 EPE27147.1 - 0.017 14.5 0.1 0.081 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 EPE27147.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EPE27147.1 - 0.018 14.5 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EPE27147.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EPE27147.1 - 0.021 14.0 0.0 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 EPE27147.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EPE27147.1 - 0.048 13.7 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EPE27147.1 - 0.051 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Histone PF00125.19 EPE27147.1 - 0.077 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NB-ARC PF00931.17 EPE27147.1 - 0.078 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF2072 PF09845.4 EPE27147.1 - 0.084 12.7 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NACHT PF05729.7 EPE27147.1 - 0.1 12.2 0.0 0.55 9.8 0.0 2.0 1 1 0 2 2 2 0 NACHT domain FGGY_C PF02782.11 EPE27148.1 - 2.3e-49 167.7 0.3 3.5e-49 167.1 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EPE27148.1 - 1.5e-22 80.1 0.2 2e-19 69.8 0.0 2.8 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain F-box-like PF12937.2 EPE27149.1 - 2.7e-07 30.2 0.3 7e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPE27149.1 - 1.2e-05 24.7 0.0 2.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain Erythro-docking PF09277.6 EPE27149.1 - 0.01 15.4 0.1 0.029 14.0 0.1 1.8 1 0 0 1 1 1 0 Erythronolide synthase, docking HSF_DNA-bind PF00447.12 EPE27150.1 - 3.6e-36 123.4 0.6 6.2e-36 122.7 0.4 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding adh_short PF00106.20 EPE27152.1 - 2.8e-23 82.6 0.5 8.5e-22 77.8 0.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE27152.1 - 3.4e-22 79.3 0.6 6.8e-21 75.1 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE27152.1 - 5e-09 36.0 0.1 3e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EPE27152.1 - 0.0066 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EPE27152.1 - 0.037 13.4 0.0 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EPE27152.1 - 0.043 13.3 0.1 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF162 PF02589.10 EPE27152.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised ACR, YkgG family COG1556 ATP-grasp_2 PF08442.5 EPE27154.1 - 3e-78 261.8 0.1 5.7e-78 260.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EPE27154.1 - 9.5e-27 93.4 1.2 2.1e-26 92.3 0.3 2.0 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EPE27154.1 - 1e-09 37.9 0.3 2e-09 36.9 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EPE27154.1 - 0.0063 16.0 0.6 0.082 12.4 0.0 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EPE27154.1 - 0.022 14.4 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Ribosomal_S11 PF00411.14 EPE27154.1 - 0.088 13.0 1.4 9.4 6.4 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein S11 DUF3245 PF11595.3 EPE27155.1 - 4.6e-08 33.4 6.0 4.6e-08 33.4 4.2 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3245) PMT PF02366.13 EPE27156.1 - 7.8e-81 271.0 16.4 7.8e-81 271.0 11.4 2.1 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPE27156.1 - 7.6e-19 67.9 0.1 7e-18 64.8 0.0 2.0 1 1 1 2 2 2 2 MIR domain Ribonuc_L-PSP PF01042.16 EPE27157.1 - 9.8e-38 128.6 0.0 1.1e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Mito_carr PF00153.22 EPE27159.1 - 5.3e-70 231.2 5.0 7.9e-24 83.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TauD PF02668.11 EPE27160.1 - 1.3e-60 205.2 1.0 2.2e-60 204.5 0.7 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EPE27160.1 - 2e-05 23.6 0.1 3.5e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 CsiD 2OG-FeII_Oxy_3 PF13640.1 EPE27160.1 - 0.0083 16.6 0.3 0.021 15.3 0.2 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF971 PF06155.7 EPE27160.1 - 0.018 15.4 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF971) 3Beta_HSD PF01073.14 EPE27162.1 - 2.9e-62 209.8 0.0 4.1e-31 107.7 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE27162.1 - 7.6e-25 87.7 0.0 5.6e-19 68.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPE27162.1 - 5.2e-11 41.9 0.2 4.4e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EPE27162.1 - 2.4e-10 39.8 0.0 2.1e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPE27162.1 - 7.4e-09 35.8 0.0 5.5e-08 33.0 0.0 2.2 1 1 1 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPE27162.1 - 3.7e-08 32.6 0.0 2.8e-07 29.7 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPE27162.1 - 0.0031 17.4 0.1 0.021 14.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EPE27162.1 - 0.0038 16.5 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 EPE27162.1 - 0.022 14.6 0.0 0.078 12.8 0.0 1.9 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EPE27162.1 - 0.023 14.3 0.2 0.47 10.1 0.1 2.3 1 1 0 1 1 1 0 KR domain UQ_con PF00179.21 EPE27163.1 - 7.7e-42 142.0 0.0 1.7e-28 98.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.8 EPE27163.1 - 0.017 14.8 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 UEV domain Cyt-b5 PF00173.23 EPE27164.1 - 5.4e-19 67.7 0.3 9e-18 63.8 0.1 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EPE27164.1 - 2.1e-08 34.5 24.3 4.8e-08 33.3 16.5 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EPE27164.1 - 0.032 14.2 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region RRM_1 PF00076.17 EPE27165.1 - 1.9e-41 139.5 0.9 1.9e-19 69.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE27165.1 - 5.3e-35 119.2 0.1 1.3e-18 66.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EPE27165.1 - 3.7e-26 91.1 0.1 8.6e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EPE27165.1 - 1.4e-22 79.2 0.0 3.1e-09 36.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPE27165.1 - 0.0063 16.3 0.0 0.056 13.3 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif MIP-T3 PF10243.4 EPE27165.1 - 0.022 13.2 20.6 0.3 9.5 15.6 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 GAS PF13851.1 EPE27166.1 - 1.8e-05 24.0 14.9 1.8e-05 24.0 10.3 1.7 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Mer2 PF09074.5 EPE27166.1 - 0.0011 18.9 4.4 0.0011 18.9 3.0 1.6 1 1 0 1 1 1 1 Mer2 Prp19 PF08606.6 EPE27166.1 - 0.015 15.0 4.4 0.015 15.0 3.0 2.2 1 1 2 3 3 3 0 Prp19/Pso4-like CALCOCO1 PF07888.6 EPE27166.1 - 0.024 12.9 13.1 0.039 12.2 9.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.9 EPE27166.1 - 0.039 13.5 18.6 0.1 12.1 12.9 1.8 1 0 0 1 1 1 0 IncA protein DUF3584 PF12128.3 EPE27166.1 - 0.074 10.3 18.0 0.11 9.7 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 EPE27166.1 - 0.16 10.9 15.5 0.32 9.9 10.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 FliJ PF02050.11 EPE27166.1 - 0.18 11.8 26.5 0.11 12.5 13.5 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein LMBR1 PF04791.11 EPE27166.1 - 0.24 9.9 6.6 0.37 9.3 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ALMT PF11744.3 EPE27166.1 - 0.38 9.3 6.9 0.61 8.6 4.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF948 PF06103.6 EPE27166.1 - 0.4 10.5 6.9 0.21 11.4 0.5 2.9 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.1 EPE27166.1 - 1 8.2 12.7 1.7 7.5 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_23 PF13476.1 EPE27166.1 - 1.3 9.3 11.6 1 9.6 6.9 1.6 2 0 0 2 2 2 0 AAA domain DUF1635 PF07795.6 EPE27166.1 - 3.6 6.8 15.1 0.083 12.2 3.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF3450 PF11932.3 EPE27166.1 - 4.3 6.5 22.7 0.27 10.4 10.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Laminin_II PF06009.7 EPE27166.1 - 4.9 6.9 14.4 3.5 7.3 8.5 1.8 2 0 0 2 2 2 0 Laminin Domain II V_ATPase_I PF01496.14 EPE27166.1 - 7.1 4.3 7.3 12 3.5 5.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EPE27166.1 - 7.6 4.8 8.9 12 4.1 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) VWA_2 PF13519.1 EPE27167.1 - 1.5e-07 31.6 0.0 2.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EPE27167.1 - 2.5e-07 30.5 0.0 1.4e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain SOG2 PF10428.4 EPE27167.1 - 0.097 11.3 0.9 0.16 10.5 0.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein EntA_Immun PF08951.5 EPE27167.1 - 0.18 11.9 0.0 0.61 10.2 0.0 1.9 2 0 0 2 2 2 0 Enterocin A Immunity zf-C2H2_4 PF13894.1 EPE27168.1 - 0.023 15.0 3.8 0.023 15.0 2.6 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger DUF629 PF04780.7 EPE27168.1 - 0.19 10.1 4.9 0.38 9.2 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF629) DUF3505 PF12013.3 EPE27168.1 - 0.23 11.7 6.7 0.15 12.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) zf-C2H2 PF00096.21 EPE27168.1 - 0.37 11.2 23.6 0.095 13.0 2.1 3.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF4611 PF15387.1 EPE27168.1 - 1 9.5 4.5 0.7 10.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-C2H2_2 PF12756.2 EPE27168.1 - 1.7 8.8 5.5 5.1 7.2 0.1 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EPE27168.1 - 8.9 6.6 9.0 4.2 7.6 0.6 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding TIM PF00121.13 EPE27170.1 - 1.5e-87 292.6 0.2 1.7e-87 292.5 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase UPF0231 PF06062.6 EPE27170.1 - 0.11 12.3 0.1 17 5.2 0.0 2.9 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0231) zf-C3HC4 PF00097.20 EPE27172.1 - 3.6e-07 29.7 7.8 6.4e-07 28.9 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE27172.1 - 7.6e-07 29.0 7.9 1.4e-06 28.2 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE27172.1 - 9.6e-07 28.3 3.7 1.5e-06 27.7 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE27172.1 - 1e-05 25.2 7.1 1.7e-05 24.5 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPE27172.1 - 0.0025 17.5 6.0 0.0048 16.5 4.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPE27172.1 - 0.0079 16.0 1.3 0.017 14.9 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EPE27172.1 - 0.01 15.6 6.9 0.02 14.7 4.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Vps39_2 PF10367.4 EPE27172.1 - 0.11 12.6 0.9 0.2 11.8 0.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-MIZ PF02891.15 EPE27172.1 - 0.73 9.3 5.5 1.7 8.2 3.8 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EPE27172.1 - 1.2 8.8 6.7 0.5 10.1 2.8 1.8 2 0 0 2 2 2 0 RING-type zinc-finger RNA_pol_Rpb1_6 PF04992.9 EPE27173.1 - 0.071 12.8 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Aminotran_1_2 PF00155.16 EPE27174.1 - 8.5e-64 215.7 0.0 1.2e-63 215.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPE27174.1 - 0.00056 19.1 0.0 0.00088 18.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EPE27174.1 - 0.0053 15.0 0.0 0.014 13.7 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EPE27174.1 - 0.0068 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPE27174.1 - 0.12 11.4 0.0 0.85 8.5 0.0 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AMP-binding PF00501.23 EPE27175.1 - 4.1e-42 144.0 0.0 5.8e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Aminotran_5 PF00266.14 EPE27175.1 - 0.0043 15.8 0.1 0.012 14.4 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Gly-zipper_OmpA PF13436.1 EPE27175.1 - 0.07 12.7 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Protoglobin PF11563.3 EPE27176.1 - 1.2e-37 128.9 0.0 4.7e-18 65.3 0.0 2.0 2 0 0 2 2 2 2 Protoglobin TPT PF03151.11 EPE27177.1 - 4.4e-37 127.0 5.8 4.4e-37 127.0 4.0 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EPE27177.1 - 6.1e-09 35.2 14.8 5.8e-08 32.0 10.3 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPE27177.1 - 0.00061 19.8 34.5 0.022 14.7 7.7 3.4 3 2 0 3 3 3 2 EamA-like transporter family F-box-like PF12937.2 EPE27178.1 - 0.001 18.7 0.2 0.0023 17.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like VEFS-Box PF09733.4 EPE27179.1 - 1.5e-12 47.3 0.1 2.7e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Tubulin_C PF03953.12 EPE27179.1 - 0.087 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Tubulin C-terminal domain Transferase PF02458.10 EPE27182.1 - 2.6e-08 32.7 0.0 1.5e-07 30.2 0.0 2.1 2 1 0 2 2 2 1 Transferase family O-FucT PF10250.4 EPE27183.1 - 0.0055 15.8 0.0 2.8 6.9 0.0 2.6 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Moulting_cycle PF04870.11 EPE27185.1 - 0.043 12.9 0.1 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Moulting cycle DUF2203 PF09969.4 EPE27185.1 - 0.053 13.7 0.5 0.14 12.3 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) UFD1 PF03152.9 EPE27186.1 - 5.6e-72 240.5 0.0 7.2e-72 240.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EPE27186.1 - 0.0032 17.0 0.1 0.0072 15.9 0.1 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 GYF PF02213.11 EPE27187.1 - 3.5e-11 42.5 0.4 7.6e-11 41.4 0.3 1.6 1 0 0 1 1 1 1 GYF domain Sorting_nexin PF03700.8 EPE27187.1 - 0.015 15.4 1.7 0.015 15.4 1.2 2.5 2 0 0 2 2 2 0 Sorting nexin, N-terminal domain tRNA-synt_1e PF01406.14 EPE27187.1 - 0.048 12.7 0.1 0.081 12.0 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Med2 PF11214.3 EPE27187.1 - 0.23 11.5 5.1 0.44 10.6 2.9 1.9 1 1 1 2 2 2 0 Mediator complex subunit 2 TIP49 PF06068.8 EPE27188.1 - 9.9e-139 462.4 3.8 1.1e-138 462.2 2.7 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 EPE27188.1 - 0.02 15.0 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EPE27189.1 - 4.2e-21 75.1 0.3 5e-21 74.8 0.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EPE27189.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Shugoshin_N PF07558.6 EPE27190.1 - 0.35 10.6 8.8 0.045 13.4 0.8 3.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Lectin_N PF03954.9 EPE27190.1 - 5.9 6.3 27.0 0.093 12.1 0.3 5.2 4 1 1 5 5 5 0 Hepatic lectin, N-terminal domain Nol1_Nop2_Fmu PF01189.12 EPE27191.1 - 7.2e-101 337.2 0.0 2.1e-99 332.4 0.0 2.2 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EPE27191.1 - 0.0031 17.1 0.0 0.0073 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EPE27191.1 - 0.0084 16.1 0.0 0.023 14.7 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Blt1 PF12754.2 EPE27192.1 - 2.4e-27 96.3 0.7 4.9e-22 78.9 0.3 2.6 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 EPE27192.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family Cofilin_ADF PF00241.15 EPE27193.1 - 1e-30 106.2 0.3 1.3e-30 105.8 0.2 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AAA_2 PF07724.9 EPE27194.1 - 3.8e-45 153.8 0.0 1.5e-43 148.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EPE27194.1 - 1.8e-27 95.0 0.3 5.8e-27 93.4 0.2 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EPE27194.1 - 2.5e-18 66.5 0.0 2.9e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPE27194.1 - 1e-12 47.9 0.0 5.5e-08 32.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPE27194.1 - 2.2e-11 44.0 7.5 5e-05 23.3 0.0 4.9 4 2 2 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 EPE27194.1 - 7e-11 42.3 0.0 0.00049 20.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EPE27194.1 - 7.7e-08 31.9 0.2 6.9e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 EPE27194.1 - 7.6e-06 25.7 3.9 0.54 9.9 0.1 4.7 3 2 0 3 3 3 2 Archaeal ATPase AAA_17 PF13207.1 EPE27194.1 - 1.8e-05 25.5 4.9 0.051 14.3 0.0 4.2 3 1 1 4 4 4 2 AAA domain NACHT PF05729.7 EPE27194.1 - 2.1e-05 24.2 0.1 0.16 11.5 0.0 2.4 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 EPE27194.1 - 3.1e-05 23.6 0.2 0.036 13.7 0.0 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EPE27194.1 - 5e-05 23.2 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPE27194.1 - 5.5e-05 23.4 6.2 0.62 10.3 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.1 EPE27194.1 - 0.00016 21.3 0.0 0.017 14.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 EPE27194.1 - 0.00023 20.6 0.0 0.29 10.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EPE27194.1 - 0.0013 18.8 0.0 0.64 10.2 0.0 2.7 2 1 0 2 2 2 1 RNA helicase SRP54 PF00448.17 EPE27194.1 - 0.0032 16.9 0.0 0.27 10.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CALCOCO1 PF07888.6 EPE27194.1 - 0.0048 15.2 7.0 0.0075 14.6 4.8 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_30 PF13604.1 EPE27194.1 - 0.0049 16.4 0.2 0.31 10.6 0.0 3.3 3 1 1 4 4 3 1 AAA domain AAA_28 PF13521.1 EPE27194.1 - 0.0076 16.2 2.3 1.4 8.8 0.0 3.8 4 1 0 4 4 3 1 AAA domain TrwB_AAD_bind PF10412.4 EPE27194.1 - 0.0086 14.7 0.0 0.86 8.1 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 EPE27194.1 - 0.0094 15.1 0.3 4.5 6.3 0.0 3.3 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EPE27194.1 - 0.011 15.9 1.4 3 8.1 0.0 3.3 3 0 0 3 3 3 0 ABC transporter Zeta_toxin PF06414.7 EPE27194.1 - 0.015 14.4 0.0 0.53 9.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.10 EPE27194.1 - 0.016 15.0 0.4 2.6 7.8 0.0 2.9 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 EPE27194.1 - 0.017 14.9 0.4 4.9 7.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EPE27194.1 - 0.018 14.4 0.3 0.14 11.5 0.0 2.7 2 2 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 EPE27194.1 - 0.019 13.8 0.2 1.5 7.6 0.1 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF815) DUF258 PF03193.11 EPE27194.1 - 0.028 13.5 0.0 6.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 PhoH PF02562.11 EPE27194.1 - 0.032 13.4 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Miro PF08477.8 EPE27194.1 - 0.036 14.5 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 EPE27194.1 - 0.036 13.6 0.0 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EPE27194.1 - 0.043 13.3 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EPE27194.1 - 0.049 13.1 0.0 2.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PIF1 PF05970.9 EPE27194.1 - 0.056 12.3 0.0 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase UPF0079 PF02367.12 EPE27194.1 - 0.057 13.0 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EPE27194.1 - 0.06 12.7 0.2 4.3 6.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF4058 PF13267.1 EPE27194.1 - 0.33 10.0 2.6 1.3 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4058) Atg14 PF10186.4 EPE27194.1 - 0.47 9.3 6.8 0.85 8.4 4.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EPE27194.1 - 0.66 9.5 12.4 1.4 8.5 8.6 1.4 1 0 0 1 1 1 0 IncA protein OEP PF02321.13 EPE27194.1 - 0.96 9.0 5.7 1.8 8.1 3.9 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein CENP-F_leu_zip PF10473.4 EPE27194.1 - 3.5 7.4 18.8 0.73 9.6 8.5 2.5 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EPE27194.1 - 6.2 5.7 9.4 10 5.0 6.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cortex-I_coil PF09304.5 EPE27194.1 - 8.1 6.5 17.2 0.52 10.3 7.1 2.4 3 0 0 3 3 2 0 Cortexillin I, coiled coil EMP24_GP25L PF01105.19 EPE27195.1 - 1.1e-47 162.1 0.0 1.2e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dioxygenase_C PF00775.16 EPE27195.1 - 0.075 12.2 0.1 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Dioxygenase Arf PF00025.16 EPE27196.1 - 3e-79 264.2 0.1 3.5e-79 264.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPE27196.1 - 1.2e-14 53.9 0.0 1.4e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EPE27196.1 - 3e-13 49.4 0.0 3.3e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EPE27196.1 - 1.1e-12 47.3 1.7 1.2e-09 37.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EPE27196.1 - 3.8e-11 42.5 0.0 4.4e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EPE27196.1 - 1.4e-08 35.2 0.0 2.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPE27196.1 - 3.4e-06 27.0 0.0 4.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPE27196.1 - 0.0067 15.8 0.2 0.053 12.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EPE27196.1 - 0.0081 15.2 0.4 0.017 14.2 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EPE27196.1 - 0.042 13.7 0.2 0.11 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain GST_C PF00043.20 EPE27197.1 - 5.3e-09 35.9 1.0 1.5e-08 34.5 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPE27197.1 - 2.1e-07 31.0 0.0 4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPE27197.1 - 7.4e-07 29.0 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPE27197.1 - 3.9e-06 26.9 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE27197.1 - 2.4e-05 24.1 0.7 0.0001 22.1 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Lactamase_B_2 PF12706.2 EPE27198.1 - 6.3e-41 140.0 0.0 8.2e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPE27198.1 - 2.6e-11 43.4 0.0 5.2e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPE27198.1 - 0.00097 18.8 2.7 0.0047 16.6 0.6 2.6 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RRM_1 PF00076.17 EPE27199.1 - 1.7e-20 72.4 0.1 2.1e-11 43.2 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE27199.1 - 1.6e-15 56.8 0.0 2e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE27199.1 - 2e-12 46.7 0.0 3.9e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ndc80_HEC PF03801.8 EPE27200.1 - 1.9e-58 196.4 0.1 4.5e-58 195.1 0.0 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family Filament PF00038.16 EPE27200.1 - 0.00016 21.2 38.9 0.011 15.1 12.6 2.3 2 0 0 2 2 2 2 Intermediate filament protein FliJ PF02050.11 EPE27200.1 - 0.0022 18.0 4.8 0.0022 18.0 3.3 3.5 2 2 1 3 3 3 1 Flagellar FliJ protein WASH_WAHD PF11945.3 EPE27200.1 - 0.52 9.5 8.7 0.037 13.3 2.1 1.9 2 0 0 2 2 2 0 WAHD domain of WASH complex Tropomyosin PF00261.15 EPE27200.1 - 0.57 9.2 49.6 0.19 10.7 9.8 3.3 2 1 1 3 3 3 0 Tropomyosin V_ATPase_I PF01496.14 EPE27200.1 - 0.88 7.3 28.0 0.92 7.2 6.2 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 EPE27200.1 - 1.1 8.3 4.3 0.53 9.4 0.8 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EPE27200.1 - 1.8 8.8 10.0 7.3 6.9 0.6 4.2 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 EPE27200.1 - 2.8 7.7 53.4 1 9.1 14.5 4.1 2 2 1 3 3 3 0 Tropomyosin like TPR_MLP1_2 PF07926.7 EPE27200.1 - 5.7 6.6 40.2 0.42 10.3 10.9 3.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein WXG100 PF06013.7 EPE27200.1 - 6.1 6.9 17.2 15 5.6 1.1 4.9 5 1 0 5 5 5 0 Proteins of 100 residues with WXG Pex14_N PF04695.8 EPE27201.1 - 1.3e-40 138.6 6.9 7.2e-40 136.1 0.0 2.9 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 EPE27201.1 - 4.1e-05 23.2 0.1 6e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 IncA protein zf-C4H2 PF10146.4 EPE27201.1 - 0.00044 20.3 0.2 0.00044 20.3 0.2 1.5 2 0 0 2 2 1 1 Zinc finger-containing protein DUF1635 PF07795.6 EPE27201.1 - 0.072 12.4 3.4 0.12 11.7 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF3584 PF12128.3 EPE27201.1 - 0.094 10.0 9.9 0.13 9.6 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3829 PF12889.2 EPE27201.1 - 0.11 11.7 3.5 0.22 10.7 2.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) GRIM-19 PF06212.7 EPE27201.1 - 0.24 11.1 3.2 0.78 9.4 0.1 2.3 2 0 0 2 2 2 0 GRIM-19 protein WD40_alt PF14077.1 EPE27201.1 - 0.34 10.5 1.6 0.42 10.2 0.2 1.8 1 1 1 2 2 2 0 Alternative WD40 repeat motif Sec2p PF06428.6 EPE27201.1 - 0.39 10.5 6.8 0.53 10.1 3.2 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF1043 PF06295.7 EPE27201.1 - 0.4 10.3 1.8 0.61 9.7 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF848 PF05852.6 EPE27201.1 - 0.51 10.1 6.3 1.1 9.0 4.4 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Baculo_PEP_C PF04513.7 EPE27201.1 - 0.54 10.0 6.2 9.5 6.0 0.1 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 EPE27201.1 - 0.65 10.4 5.9 0.71 10.3 1.7 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal V-SNARE PF05008.10 EPE27201.1 - 0.78 9.9 7.0 7.7 6.7 3.3 2.5 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Sipho_Gp157 PF05565.6 EPE27201.1 - 0.84 9.2 5.0 1.6 8.2 2.9 1.8 1 1 0 1 1 1 0 Siphovirus Gp157 SlyX PF04102.7 EPE27201.1 - 0.85 10.0 6.7 0.2 12.0 0.5 2.9 3 1 1 4 4 3 0 SlyX ERM PF00769.14 EPE27201.1 - 0.86 9.0 13.1 1.8 8.0 9.1 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TBPIP PF07106.8 EPE27201.1 - 2 7.9 7.1 0.87 9.1 2.1 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Transposase_22 PF02994.9 EPE27201.1 - 2.8 6.3 8.5 0.58 8.5 3.1 1.9 1 1 2 3 3 3 0 L1 transposable element Spectrin PF00435.16 EPE27201.1 - 4.4 7.6 8.6 53 4.1 6.1 2.3 1 1 0 1 1 1 0 Spectrin repeat DUF972 PF06156.8 EPE27201.1 - 7.6 6.9 6.0 5.3 7.4 1.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Use1 PF09753.4 EPE27201.1 - 8.1 5.8 10.5 4.2 6.7 2.5 2.1 1 1 1 2 2 2 0 Membrane fusion protein Use1 Abhydrolase_3 PF07859.8 EPE27202.1 - 1.5e-39 135.7 0.2 1.5e-38 132.5 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EPE27202.1 - 6.3e-05 21.7 0.0 0.00011 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPE27202.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family HMG_CoA_synt_C PF08540.5 EPE27203.1 - 3.4e-103 345.0 0.4 4.4e-103 344.6 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EPE27203.1 - 2.5e-95 316.9 0.3 3.8e-95 316.3 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal PSK_trans_fac PF07704.6 EPE27203.1 - 0.07 13.8 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Rv0623-like transcription factor RRM_1 PF00076.17 EPE27204.1 - 2.3e-23 81.5 0.0 3e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE27204.1 - 4.5e-17 61.7 0.0 5.6e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE27204.1 - 3.6e-09 36.3 0.0 4.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ChaC PF04752.7 EPE27205.1 - 9.3e-51 172.3 0.0 3.8e-50 170.3 0.0 1.8 1 1 0 1 1 1 1 ChaC-like protein Flocculin PF00624.13 EPE27205.1 - 0.13 12.0 2.2 0.23 11.3 1.5 1.4 1 0 0 1 1 1 0 Flocculin repeat EF-hand_1 PF00036.27 EPE27206.1 - 1.1e-14 52.5 1.0 4.6e-06 25.5 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EPE27206.1 - 4.5e-14 51.7 1.7 1.8e-09 37.0 0.0 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EPE27206.1 - 3.9e-10 38.7 1.1 0.011 15.5 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EPE27206.1 - 5.5e-10 39.2 0.1 2e-05 24.6 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EPE27206.1 - 4.2e-09 35.3 2.8 0.0046 16.2 0.0 4.2 4 0 0 4 4 4 3 EF hand DUF3315 PF11776.3 EPE27207.1 - 0.089 12.3 0.4 0.18 11.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3315) Myb_DNA-binding PF00249.26 EPE27209.1 - 4.7e-22 77.7 1.3 2.2e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPE27209.1 - 6.9e-18 64.4 0.8 2.2e-12 46.8 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_38 PF13936.1 EPE27209.1 - 0.036 13.6 0.1 0.084 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2774 PF11242.3 EPE27209.1 - 0.041 13.8 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EPE27209.1 - 0.14 11.6 0.0 0.35 10.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Glyco_transf_41 PF13844.1 EPE27210.1 - 9.2e-96 320.6 0.1 2.6e-50 170.7 0.0 3.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EPE27210.1 - 8.1e-22 76.6 12.4 6.7e-09 35.2 0.2 4.5 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 EPE27210.1 - 2.9e-15 55.1 6.2 0.00019 20.9 0.0 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EPE27210.1 - 5.3e-14 50.9 8.5 0.005 16.6 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPE27210.1 - 1.2e-11 44.4 7.3 8.2e-07 28.8 0.2 4.2 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPE27210.1 - 7.6e-11 41.3 2.2 0.053 13.7 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPE27210.1 - 6.8e-10 38.6 3.2 0.00021 21.6 0.2 5.7 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE27210.1 - 1.7e-09 36.7 1.6 0.0016 18.0 0.1 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE27210.1 - 6e-09 36.3 6.9 0.04 14.6 0.6 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPE27210.1 - 1.4e-08 33.8 1.3 0.11 12.3 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPE27210.1 - 3.7e-07 29.8 11.4 0.056 13.4 0.4 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPE27210.1 - 4.8e-06 26.8 4.5 0.06 13.6 0.1 3.6 3 2 2 5 5 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EPE27210.1 - 0.00049 20.1 2.5 0.19 11.8 0.3 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 EPE27210.1 - 0.032 14.5 0.3 2.3 8.4 0.0 2.8 3 0 0 3 3 2 0 Bacterial transcriptional activator domain TPR_15 PF13429.1 EPE27210.1 - 0.044 12.8 0.2 0.23 10.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPE27210.1 - 0.95 10.0 5.1 2 9.0 0.0 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat Sec23_trunk PF04811.10 EPE27211.1 - 3.8e-80 268.7 0.0 5.9e-80 268.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPE27211.1 - 2.5e-34 116.7 0.7 5.4e-34 115.7 0.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPE27211.1 - 3.4e-30 104.4 0.3 7.5e-30 103.3 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Ribosomal_L11_N PF03946.9 EPE27211.1 - 5.9e-16 57.6 0.0 5.9e-16 57.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Gelsolin PF00626.17 EPE27211.1 - 1e-10 41.1 0.0 2.3e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11 PF00298.14 EPE27211.1 - 1.9e-09 37.4 0.3 4.5e-09 36.3 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain zf-Sec23_Sec24 PF04810.10 EPE27211.1 - 2.2e-07 30.3 0.1 4.3e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Aa_trans PF01490.13 EPE27212.1 - 7.1e-41 140.0 38.4 8.5e-41 139.7 26.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EPE27212.1 - 3.1e-06 26.2 22.8 5.8e-06 25.3 15.8 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DCP1 PF06058.8 EPE27213.1 - 6.5e-16 58.4 0.0 8.8e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family Vps39_2 PF10367.4 EPE27214.1 - 6.2e-07 29.5 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EPE27214.1 - 0.0014 18.6 0.0 0.11 12.5 0.0 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 EPE27214.1 - 0.0017 17.9 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS CASP_C PF08172.7 EPE27215.1 - 2.5e-89 298.5 2.8 2.5e-89 298.5 1.9 3.2 2 1 0 3 3 3 1 CASP C terminal TPR_MLP1_2 PF07926.7 EPE27215.1 - 0.0075 16.0 40.1 0.026 14.2 1.7 5.6 4 3 0 4 4 4 2 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EPE27215.1 - 0.0078 15.1 35.1 0.23 10.3 4.8 4.5 4 1 1 5 5 5 3 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 EPE27215.1 - 0.11 12.3 48.5 0.36 10.6 6.5 5.4 4 1 1 5 5 5 0 Tropomyosin like DUF972 PF06156.8 EPE27215.1 - 0.35 11.2 29.6 1.3 9.4 0.1 5.9 4 2 1 6 6 6 0 Protein of unknown function (DUF972) SlyX PF04102.7 EPE27215.1 - 1.4 9.3 0.0 1.4 9.3 0.0 5.2 7 0 0 7 7 6 0 SlyX V_ATPase_I PF01496.14 EPE27215.1 - 2.8 5.7 26.5 0.76 7.5 6.0 4.0 2 1 2 4 4 4 0 V-type ATPase 116kDa subunit family Tropomyosin PF00261.15 EPE27215.1 - 3.7 6.5 43.4 1.1 8.3 0.6 4.2 3 1 0 3 3 3 0 Tropomyosin ADIP PF11559.3 EPE27215.1 - 3.7 7.4 56.4 0.14 12.0 2.7 6.8 4 1 2 7 7 7 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EPE27215.1 - 6.4 6.3 52.8 0.67 9.5 0.1 6.0 3 1 1 5 5 4 0 IncA protein DUF4140 PF13600.1 EPE27215.1 - 8.5 6.8 36.8 0.65 10.4 0.5 6.5 6 1 1 7 7 7 0 N-terminal domain of unknown function (DUF4140) DUF1515 PF07439.6 EPE27215.1 - 9.3 6.1 12.6 0.71 9.7 0.5 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1515) DUF3455 PF11937.3 EPE27216.1 - 1.5e-48 165.0 0.2 2.1e-48 164.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Mis12 PF05859.7 EPE27217.1 - 4.6e-39 133.5 0.0 7.2e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein PPR_2 PF13041.1 EPE27218.1 - 1.1e-32 111.7 0.0 1.4e-09 37.7 0.0 8.1 5 3 3 8 8 8 7 PPR repeat family PPR_3 PF13812.1 EPE27218.1 - 5.6e-22 76.1 2.0 0.081 13.2 0.0 10.6 11 0 0 11 11 11 5 Pentatricopeptide repeat domain PPR PF01535.15 EPE27218.1 - 6.1e-15 54.0 0.2 0.1 12.5 0.1 8.1 9 0 0 9 9 9 4 PPR repeat PPR_1 PF12854.2 EPE27218.1 - 2.3e-13 49.3 0.1 0.00083 18.7 0.0 6.7 7 0 0 7 7 7 4 PPR repeat MRP-S27 PF10037.4 EPE27218.1 - 0.31 9.9 0.0 0.72 8.6 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 FAD_binding_3 PF01494.14 EPE27220.1 - 3.6e-05 22.9 1.4 0.00059 18.9 0.0 2.7 3 1 0 3 3 3 1 FAD binding domain SE PF08491.5 EPE27220.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Metal_resist PF13801.1 EPE27220.1 - 0.11 12.4 0.1 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Heavy-metal resistance DEAD PF00270.24 EPE27221.1 - 1e-43 148.7 0.0 2e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EPE27221.1 - 2.6e-22 78.1 0.3 6e-22 76.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EPE27221.1 - 1.7e-19 69.4 0.0 4.7e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE27221.1 - 0.03 14.1 1.6 0.16 11.7 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF159 PF02586.9 EPE27222.1 - 1.3e-58 197.9 0.1 1.8e-58 197.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Mif2_N PF15624.1 EPE27222.1 - 1.2 9.7 8.8 3 8.4 6.1 1.7 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cellulase PF00150.13 EPE27223.1 - 1.5e-48 165.4 0.0 2e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_6 PF01341.12 EPE27224.1 - 6.1e-110 367.3 1.3 7.4e-110 367.0 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EPE27224.1 - 2e-08 33.7 9.4 7.9e-08 31.8 6.5 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_61 PF03443.9 EPE27225.1 - 5e-39 134.3 0.1 6.6e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 EPE27226.1 - 5.5e-65 219.2 0.1 6.4e-65 219.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Med1 PF10744.4 EPE27227.1 - 1.2e-41 142.8 0.0 3e-41 141.4 0.0 1.6 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 AIM24 PF01987.12 EPE27230.1 - 8e-56 188.8 0.1 9.8e-56 188.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.12 EPE27231.1 - 1.6e-45 153.7 0.4 2.5e-45 153.1 0.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EPE27231.1 - 0.072 13.4 0.1 0.26 11.6 0.0 2.1 1 0 0 1 1 1 0 Restriction alleviation protein Lar Daxx PF03344.10 EPE27231.1 - 1 7.7 14.3 1.4 7.3 9.9 1.1 1 0 0 1 1 1 0 Daxx Family zf-HYPF PF07503.7 EPE27231.1 - 1.9 7.9 6.7 6.7 6.2 3.1 2.7 2 1 1 3 3 3 0 HypF finger Arc_trans_TRASH PF08394.5 EPE27231.1 - 2.1 8.5 6.7 2 8.6 0.2 2.9 1 1 1 2 2 2 0 Archaeal TRASH domain NTR2 PF15458.1 EPE27231.1 - 6.7 5.8 19.3 26 3.9 13.4 1.9 1 1 0 1 1 1 0 Nineteen complex-related protein 2 MARVEL PF01284.18 EPE27233.1 - 7.3e-28 97.1 13.0 8.8e-28 96.9 9.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 EPE27233.1 - 3.1 7.3 11.0 1.3 8.5 5.8 1.6 1 1 0 1 1 1 0 SUR7/PalI family MpPF26 PF07666.6 EPE27233.1 - 3.4 7.5 5.6 1.1 9.1 1.2 2.2 2 1 0 2 2 2 0 M penetrans paralogue family 26 UbiA PF01040.13 EPE27234.1 - 1.6e-34 119.3 21.9 2.1e-34 118.8 15.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.17 EPE27235.1 - 2.1e-08 34.3 0.2 6.5e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EPE27235.1 - 3.9e-06 26.9 9.1 3.9e-06 26.9 6.3 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EPE27235.1 - 0.031 13.7 0.1 0.099 12.1 0.0 1.8 2 0 0 2 2 2 0 Cupin domain DUF1772 PF08592.6 EPE27237.1 - 0.0026 17.5 0.1 0.0048 16.6 0.0 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) EthD PF07110.6 EPE27238.1 - 0.00014 22.7 0.2 0.00021 22.1 0.2 1.3 1 1 0 1 1 1 1 EthD domain Glyco_hydro_16 PF00722.16 EPE27239.1 - 2.2e-15 56.4 0.1 4.1e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EPE27239.1 - 1.9e-05 23.0 1.1 0.059 11.5 0.1 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Collagen_bind PF05737.7 EPE27239.1 - 0.066 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Collagen binding domain PS_Dcarbxylase PF02666.10 EPE27240.1 - 6.8e-52 175.6 0.0 1e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EPE27240.1 - 6.6e-33 112.4 0.2 3.7e-15 55.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EPE27240.1 - 0.00038 20.5 0.1 0.0014 18.6 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPE27240.1 - 0.0013 18.4 0.1 0.04 13.8 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EPE27240.1 - 0.0018 17.4 0.0 0.0077 15.4 0.0 2.2 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EPE27240.1 - 0.032 13.5 0.0 0.12 11.7 0.0 2.0 1 0 0 1 1 1 0 EF hand HAD PF12710.2 EPE27241.1 - 2e-10 41.1 0.0 3.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPE27241.1 - 0.00033 19.8 0.0 0.00078 18.6 0.0 1.5 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.21 EPE27241.1 - 0.069 13.5 0.3 0.53 10.6 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EPE27241.1 - 0.074 12.3 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Pkinase PF00069.20 EPE27244.1 - 6.1e-26 91.1 0.0 9e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE27244.1 - 1.5e-10 40.6 0.0 1.6e-09 37.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Fungal_trans_2 PF11951.3 EPE27245.1 - 1.9e-06 26.7 0.2 3.7e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27245.1 - 0.00016 21.5 5.6 0.00016 21.5 3.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Per1 PF04080.8 EPE27246.1 - 0.17 11.3 3.9 0.22 10.9 2.7 1.1 1 0 0 1 1 1 0 Per1-like ATPase_gene1 PF09527.5 EPE27246.1 - 0.27 11.0 3.4 0.19 11.5 0.3 2.2 2 1 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) APH PF01636.18 EPE27247.1 - 1.6e-11 44.4 0.0 2.2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE27247.1 - 6.8e-05 22.5 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPE27247.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase C1_1 PF00130.17 EPE27248.1 - 0.025 14.3 0.8 0.036 13.7 0.5 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Tnp_zf-ribbon_2 PF13842.1 EPE27248.1 - 0.14 12.5 1.5 0.23 11.9 1.1 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Ank PF00023.25 EPE27249.1 - 8.6e-17 60.0 2.6 1.1e-05 24.9 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EPE27249.1 - 4.6e-15 55.7 1.3 8.6e-08 32.4 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE27249.1 - 2e-14 53.6 0.4 1.2e-07 32.0 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE27249.1 - 5.4e-11 42.3 3.0 0.0012 19.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE27249.1 - 6.5e-11 41.3 0.8 0.02 15.0 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EPE27249.1 - 2e-06 27.3 0.1 1.1e-05 24.9 0.1 2.2 1 1 0 1 1 1 1 KilA-N domain FbpA PF05833.6 EPE27249.1 - 0.0018 16.8 3.3 0.0032 16.0 2.3 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) FliL PF03748.9 EPE27249.1 - 0.18 11.8 7.0 0.32 11.0 2.9 2.8 2 1 1 3 3 3 0 Flagellar basal body-associated protein FliL Sugar_tr PF00083.19 EPE27250.1 - 2.7e-83 280.0 21.6 5.6e-82 275.6 15.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE27250.1 - 1.9e-33 115.6 31.5 2.1e-32 112.2 17.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EPE27251.1 - 5.4e-62 209.2 0.0 6.8e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE27251.1 - 8.4e-30 103.6 0.0 1.6e-29 102.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE27251.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPE27251.1 - 0.032 13.9 0.0 0.16 11.7 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.16 EPE27252.1 - 3.3e-74 247.8 0.1 3.9e-74 247.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EPE27252.1 - 7.4e-12 44.6 2.4 1.8e-08 33.5 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EPE27252.1 - 9e-12 44.6 0.0 1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EPE27252.1 - 1.5e-11 43.8 0.0 1.9e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPE27252.1 - 1.1e-10 41.1 0.0 1.3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EPE27252.1 - 8.6e-08 32.7 0.0 1.3e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPE27252.1 - 9.6e-05 22.3 0.1 0.00039 20.3 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EPE27252.1 - 0.02 14.0 0.3 0.037 13.0 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF1325 PF07039.6 EPE27253.1 - 3.2e-20 72.0 0.1 8e-20 70.7 0.0 1.7 2 0 0 2 2 2 1 SGF29 tudor-like domain PMI_typeI PF01238.16 EPE27254.1 - 1.3e-144 481.8 0.1 1.5e-144 481.5 0.1 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I SATase_N PF06426.9 EPE27254.1 - 0.063 13.5 0.1 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Fungal_trans_2 PF11951.3 EPE27255.1 - 3.2e-16 58.9 0.0 1e-15 57.2 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.6 EPE27256.1 - 2e-23 83.1 0.0 4.6e-23 81.9 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.3 EPE27257.1 - 1.4e-06 27.2 0.9 1.8e-06 26.8 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27257.1 - 0.00013 21.7 1.2 0.00025 20.8 0.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_FMN PF00724.15 EPE27258.1 - 2e-55 188.1 0.0 2.4e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 EPE27258.1 - 0.017 14.3 0.1 0.51 9.5 0.0 3.0 3 1 1 4 4 4 0 Xylose isomerase-like TIM barrel GTP_cyclohydro2 PF00925.15 EPE27259.1 - 2.9e-59 199.0 0.1 3.8e-54 182.4 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II AA_permease_2 PF13520.1 EPE27260.1 - 7.9e-63 212.4 48.4 9.5e-63 212.1 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE27260.1 - 2.9e-18 65.4 45.4 3.7e-18 65.1 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease HET PF06985.6 EPE27261.1 - 3.4e-18 66.1 0.0 7.5e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.13 EPE27262.1 - 2.2e-06 27.4 7.0 5e-06 26.3 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE27262.1 - 0.018 13.9 0.2 0.034 13.0 0.1 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF3328 PF11807.3 EPE27263.1 - 2.1e-24 86.4 0.5 3e-24 85.9 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NifW PF03206.9 EPE27263.1 - 0.3 11.2 1.3 0.6 10.2 0.9 1.4 1 0 0 1 1 1 0 Nitrogen fixation protein NifW HET PF06985.6 EPE27264.1 - 4.9e-35 120.6 4.4 1.5e-34 119.1 3.1 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.8 EPE27265.1 - 1.7e-11 43.8 0.0 1.9e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE27265.1 - 5.7e-09 36.2 0.0 1.2e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EPE27265.1 - 0.0013 17.7 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EPE27265.1 - 0.0042 17.1 0.0 0.0064 16.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase CFEM PF05730.6 EPE27267.1 - 0.017 14.9 9.9 0.043 13.6 6.9 1.6 1 1 0 1 1 1 0 CFEM domain Acyl-CoA_dh_1 PF00441.19 EPE27268.1 - 2.5e-23 82.8 0.4 4.4e-23 82.0 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPE27268.1 - 2e-09 36.8 0.9 3.7e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EPE27268.1 - 2.5e-07 31.2 0.0 4.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EPE27268.1 - 1.6e-06 28.3 1.2 3.3e-06 27.3 0.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HARE-HTH PF05066.8 EPE27269.1 - 0.032 14.5 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain DEAD PF00270.24 EPE27272.1 - 6e-33 113.7 0.0 9.2e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE27272.1 - 1.5e-22 79.2 0.1 2.9e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EPE27272.1 - 0.0063 16.2 0.2 0.055 13.2 0.0 2.4 3 0 0 3 3 3 1 Part of AAA domain DUF2999 PF11212.3 EPE27272.1 - 0.097 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) AAA_30 PF13604.1 EPE27272.1 - 0.11 11.9 0.0 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain C1-set PF07654.10 EPE27272.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin C1-set domain FCH PF00611.18 EPE27273.1 - 4.3e-24 84.5 0.5 3e-23 81.8 0.0 2.7 2 1 1 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EPE27273.1 - 2e-20 72.0 0.7 1e-12 47.4 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EPE27273.1 - 4.8e-16 57.8 0.3 6.7e-08 31.8 0.1 2.5 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 EPE27273.1 - 1.3e-14 53.5 5.6 2.1e-14 52.9 3.9 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 EPE27273.1 - 9.2e-05 22.5 1.6 0.0069 16.5 0.4 2.6 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_2 PF07653.12 EPE27273.1 - 0.00055 19.3 0.1 0.3 10.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Ax_dynein_light PF10211.4 EPE27273.1 - 0.0069 16.2 5.0 0.0069 16.2 3.5 3.0 4 0 0 4 4 4 1 Axonemal dynein light chain Allexi_40kDa PF05549.6 EPE27273.1 - 0.026 13.8 0.4 0.11 11.7 0.0 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein COG2 PF06148.6 EPE27273.1 - 0.26 11.1 5.0 0.85 9.4 1.3 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 C1_2 PF03107.11 EPE27273.1 - 0.54 10.4 7.8 0.96 9.6 5.4 1.4 1 0 0 1 1 1 0 C1 domain BCDHK_Adom3 PF10436.4 EPE27274.1 - 4.4e-70 234.4 0.0 6.6e-70 233.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EPE27274.1 - 2e-17 62.8 0.0 4.2e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EPE27274.1 - 0.0097 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Beta-Casp PF10996.3 EPE27276.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Beta-Casp domain PRCC PF10253.4 EPE27280.1 - 0.51 10.9 2.8 0.55 10.8 2.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF605 PF04652.11 EPE27280.1 - 4.2 6.6 14.6 5 6.4 10.1 1.1 1 0 0 1 1 1 0 Vta1 like Pol_alpha_B_N PF08418.5 EPE27280.1 - 4.6 6.7 10.8 5.1 6.5 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF2746 PF10874.3 EPE27281.1 - 0.19 11.9 0.7 0.49 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Adeno_terminal PF02459.10 EPE27284.1 - 0.015 13.4 3.4 0.024 12.8 2.3 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein YqgF PF14639.1 EPE27284.1 - 0.086 12.3 0.4 0.18 11.3 0.3 1.5 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Glyco_hydro_72 PF03198.9 EPE27286.1 - 5.5e-131 436.2 0.1 6.7e-131 435.9 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EPE27286.1 - 0.00015 21.0 0.1 0.00077 18.7 0.0 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EPE27286.1 - 0.0031 16.4 0.0 0.0051 15.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Pyridoxal_deC PF00282.14 EPE27288.1 - 7.2e-18 64.1 0.0 1.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EPE27288.1 - 5.2e-07 28.7 0.0 1.3e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPE27288.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_34 PF05637.7 EPE27289.1 - 6.7e-71 238.5 0.0 8e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EPE27289.1 - 0.0031 16.8 0.0 0.23 10.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF273 PMI_typeI PF01238.16 EPE27290.1 - 6.6e-74 249.1 0.0 4.9e-72 242.9 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 EPE27290.1 - 7.1e-05 22.5 0.0 0.0046 16.6 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.6 EPE27290.1 - 0.00011 21.6 0.1 0.19 11.2 0.0 2.4 2 0 0 2 2 2 2 Cupin domain RINGv PF12906.2 EPE27291.1 - 5e-10 39.2 5.2 1.4e-09 37.8 1.2 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EPE27291.1 - 0.00098 18.9 4.9 0.0054 16.5 1.2 2.2 2 0 0 2 2 2 1 Ring finger domain SurA_N_3 PF13624.1 EPE27291.1 - 0.028 14.4 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 SurA N-terminal domain Proteasome PF00227.21 EPE27292.1 - 1.2e-57 194.2 0.0 2.2e-33 115.1 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EPE27292.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RCC1_2 PF13540.1 EPE27293.1 - 3.8e-10 39.0 5.1 0.024 14.2 0.0 5.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EPE27293.1 - 1e-08 35.2 2.9 0.054 13.7 0.1 4.9 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat HSP70 PF00012.15 EPE27294.1 - 7.4e-11 40.6 0.0 3.1e-09 35.3 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein DUF4201 PF13870.1 EPE27296.1 - 0.0041 16.5 8.6 0.0088 15.5 6.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) Lebercilin PF15619.1 EPE27296.1 - 0.058 12.8 10.2 0.032 13.6 3.2 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Tup_N PF08581.5 EPE27296.1 - 0.33 11.1 8.9 0.63 10.2 1.2 2.6 1 1 0 2 2 2 0 Tup N-terminal IncA PF04156.9 EPE27296.1 - 0.36 10.3 12.9 3.3 7.2 9.1 2.1 1 1 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 EPE27296.1 - 1.1 8.9 11.5 0.62 9.7 0.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.1 EPE27296.1 - 4.2 7.3 14.9 1.3 9.0 1.9 3.1 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Bap31 PF05529.7 EPE27296.1 - 5.5 6.4 6.0 5.7 6.3 0.2 2.3 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF904 PF06005.7 EPE27296.1 - 7.2 6.9 8.8 35 4.7 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 EPE27296.1 - 9.7 3.8 6.5 12 3.5 0.9 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Hpt PF01627.18 EPE27297.1 - 1.1e-13 51.0 0.1 1.7e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Hpt domain GrpE PF01025.14 EPE27297.1 - 0.16 11.4 2.4 1 8.9 0.2 2.1 2 0 0 2 2 2 0 GrpE YkyA PF10368.4 EPE27297.1 - 1 8.6 7.3 0.26 10.5 0.5 2.4 2 1 0 3 3 3 0 Putative cell-wall binding lipoprotein Sigma70_ner PF04546.8 EPE27297.1 - 5.4 6.5 8.8 2 7.9 1.7 2.0 1 1 1 2 2 2 0 Sigma-70, non-essential region AKAP7_NLS PF10469.4 EPE27299.1 - 4.7e-27 95.0 0.0 6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 EPE27299.1 - 0.00027 20.6 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Ribonuclease_3 PF00636.21 EPE27300.1 - 1.4e-39 135.0 0.0 2.3e-19 69.9 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.9 EPE27300.1 - 7.5e-21 73.7 0.0 3e-20 71.7 0.0 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 EPE27300.1 - 1.2e-19 70.5 0.1 3e-08 33.6 0.0 3.7 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.26 EPE27300.1 - 3.1e-15 55.7 0.0 8.9e-15 54.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPE27300.1 - 1.3e-07 31.3 0.1 7.1e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EPE27300.1 - 0.022 14.5 0.0 0.063 13.1 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 EPE27300.1 - 0.04 13.3 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 Pkinase PF00069.20 EPE27301.1 - 2.6e-58 197.1 0.0 4e-58 196.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE27301.1 - 1.4e-32 112.8 0.0 4.1e-31 107.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EPE27301.1 - 0.015 14.0 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stc1 PF12898.2 EPE27302.1 - 1.2e-08 34.8 9.7 3.5e-08 33.3 6.7 1.9 1 0 0 1 1 1 1 Stc1 domain Chorismate_bind PF00425.13 EPE27305.1 - 5.1e-86 288.1 0.0 1.7e-84 283.1 0.0 2.1 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EPE27305.1 - 4.5e-27 94.7 0.0 1.1e-24 87.0 0.0 3.3 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Dzip-like_N PF13815.1 EPE27305.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal AAA_32 PF13654.1 EPE27306.1 - 0.021 13.4 7.5 0.017 13.8 4.3 1.4 1 1 0 1 1 1 0 AAA domain DUF4446 PF14584.1 EPE27306.1 - 0.76 9.5 7.1 1.1 9.0 0.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) IncA PF04156.9 EPE27306.1 - 0.84 9.2 9.4 1.6 8.2 6.5 1.5 1 0 0 1 1 1 0 IncA protein Zn_clus PF00172.13 EPE27307.1 - 4.6e-08 32.8 7.0 7.9e-08 32.0 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE27307.1 - 1.7e-05 23.6 1.1 3.2e-05 22.7 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EPE27308.1 - 1.2e-93 314.2 28.5 1.4e-93 313.9 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE27308.1 - 1.3e-22 79.9 51.1 9.6e-21 73.8 15.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SOBP PF15279.1 EPE27309.1 - 6.1 7.1 9.6 7.5 6.8 6.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4064 PF13273.1 EPE27310.1 - 0.00089 19.3 4.5 0.63 10.1 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF4064) Virul_fac_BrkB PF03631.10 EPE27310.1 - 0.007 15.7 3.7 0.007 15.7 2.5 1.7 2 0 0 2 2 2 1 Virulence factor BrkB Mannosyl_trans PF05007.8 EPE27310.1 - 0.042 13.4 0.2 0.042 13.4 0.1 2.2 2 1 0 2 2 2 0 Mannosyltransferase (PIG-M) SUR7 PF06687.7 EPE27310.1 - 0.12 11.8 6.1 1.1 8.7 4.2 2.1 1 1 0 1 1 1 0 SUR7/PalI family PRA1 PF03208.14 EPE27310.1 - 2.8 7.2 6.8 0.68 9.2 1.6 2.0 2 0 0 2 2 2 0 PRA1 family protein CcmD PF04995.9 EPE27310.1 - 5.3 6.8 6.0 8.1 6.2 0.1 2.9 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) DUF2721 PF11026.3 EPE27310.1 - 8.7 5.9 11.4 6.7 6.3 1.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Rrn6 PF10214.4 EPE27311.1 - 1.7e-91 307.5 2.5 2.2e-91 307.2 1.8 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 EPE27312.1 - 1.5e-21 76.1 0.1 1.5e-21 76.1 0.1 2.1 3 0 0 3 3 3 1 Chromosome segregation protein Spc25 Polysacc_deac_3 PF15421.1 EPE27312.1 - 0.019 13.6 1.0 0.026 13.2 0.4 1.4 1 1 0 1 1 1 0 Putative polysaccharide deacetylase Cortex-I_coil PF09304.5 EPE27312.1 - 0.093 12.7 11.5 0.42 10.6 7.6 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil Rgp1 PF08737.5 EPE27312.1 - 0.11 11.5 5.7 0.15 11.1 3.9 1.1 1 0 0 1 1 1 0 Rgp1 Filament PF00038.16 EPE27312.1 - 4.4 6.6 20.5 1.1 8.6 11.0 2.1 2 1 0 2 2 2 0 Intermediate filament protein MOZART1 PF12554.3 EPE27313.1 - 2.8e-25 87.4 0.5 3.4e-25 87.2 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Npa1 PF11707.3 EPE27313.1 - 0.076 12.0 0.1 0.091 11.7 0.0 1.0 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal GFA PF04828.9 EPE27314.1 - 1.5e-15 56.8 1.7 2.3e-15 56.3 1.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cytochrom_C PF00034.16 EPE27316.1 - 9.5e-09 35.9 0.0 1.9e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EPE27316.1 - 5.1e-07 29.7 2.1 4e-06 26.8 1.5 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EPE27316.1 - 0.00018 20.9 0.5 0.0012 18.2 0.4 2.0 1 1 0 1 1 1 1 Cytochrome c-550 domain ATP-synt_A PF00119.15 EPE27317.1 - 0.11 11.9 0.4 0.15 11.5 0.3 1.1 1 0 0 1 1 1 0 ATP synthase A chain LSM PF01423.17 EPE27318.1 - 1.4e-12 46.9 0.0 2.2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain NUDIX PF00293.23 EPE27319.1 - 4.4e-15 55.5 0.3 6e-15 55.0 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain ATE_C PF04377.10 EPE27321.1 - 5.6e-44 149.2 0.2 8.5e-44 148.7 0.2 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus adh_short PF00106.20 EPE27322.1 - 9.5e-17 61.4 0.4 1.6e-16 60.6 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE27322.1 - 5.6e-08 32.6 0.1 8.6e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPE27322.1 - 0.032 14.0 0.2 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RNase_PH PF01138.16 EPE27323.1 - 3.1e-16 59.8 0.0 7.6e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EPE27323.1 - 0.0083 16.0 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MC1 PF05854.6 EPE27325.1 - 0.039 13.9 0.7 0.09 12.7 0.5 1.6 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 PAT1 PF09770.4 EPE27325.1 - 1.7 6.8 5.2 1.7 6.7 3.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lipase_GDSL_2 PF13472.1 EPE27326.1 - 1.2e-16 61.4 0.8 1.4e-16 61.1 0.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE27326.1 - 3e-09 37.0 1.4 4.1e-09 36.6 1.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EPE27326.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family TRP PF06011.7 EPE27327.1 - 1.8e-161 537.5 31.4 2.2e-161 537.3 21.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPE27327.1 - 9.2e-43 145.6 0.7 1.6e-42 144.8 0.5 1.4 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 EPE27327.1 - 0.00078 18.8 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Glycoprotein UL132 VirB3 PF05101.8 EPE27327.1 - 0.069 13.1 9.8 0.29 11.1 1.4 3.1 2 1 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein 4HBT PF03061.17 EPE27328.1 - 1.7e-05 24.8 0.5 0.011 15.8 0.1 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Snf7 PF03357.16 EPE27329.1 - 6.4e-23 80.9 15.1 4.4e-19 68.5 4.1 2.2 1 1 1 2 2 2 2 Snf7 GSH_synth_ATP PF03917.12 EPE27329.1 - 0.051 12.1 0.7 0.064 11.8 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain PMSR PF01625.16 EPE27329.1 - 0.19 11.6 1.2 6 6.7 0.1 2.1 1 1 1 2 2 2 0 Peptide methionine sulfoxide reductase AAA PF00004.24 EPE27330.1 - 1.6e-90 300.1 0.0 6.2e-46 155.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPE27330.1 - 1.9e-14 53.2 0.0 4e-06 26.0 0.0 2.5 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPE27330.1 - 1.6e-12 47.7 0.0 3.6e-05 23.8 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EPE27330.1 - 1.3e-10 41.4 0.1 0.0036 17.4 0.0 4.6 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EPE27330.1 - 3.4e-10 40.0 0.0 0.0012 18.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EPE27330.1 - 4.2e-10 39.6 0.0 0.001 18.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EPE27330.1 - 4.6e-10 39.3 0.3 0.0017 18.1 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPE27330.1 - 8.4e-10 39.5 0.1 0.00046 20.9 0.0 3.2 3 1 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EPE27330.1 - 1.4e-09 37.3 0.0 0.00061 18.9 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_33 PF13671.1 EPE27330.1 - 4.6e-09 36.2 0.0 0.0039 17.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPE27330.1 - 8.6e-09 35.0 1.6 0.0028 17.3 0.0 3.8 5 1 0 5 5 3 2 Part of AAA domain TIP49 PF06068.8 EPE27330.1 - 3.1e-08 32.7 0.1 0.0015 17.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EPE27330.1 - 4.9e-08 32.5 0.0 0.0061 15.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 EPE27330.1 - 9.5e-08 31.6 5.9 0.52 9.6 0.0 4.9 3 2 1 5 5 4 3 AAA domain RNA_helicase PF00910.17 EPE27330.1 - 1.7e-07 31.3 0.0 0.013 15.7 0.0 2.7 2 1 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EPE27330.1 - 3e-07 29.8 0.2 0.026 13.6 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EPE27330.1 - 8.2e-07 28.8 0.2 0.097 12.3 0.0 3.6 2 2 1 3 3 3 2 NACHT domain KaiC PF06745.8 EPE27330.1 - 1e-06 28.0 0.6 0.012 14.7 0.0 3.6 4 0 0 4 4 3 2 KaiC AAA_3 PF07726.6 EPE27330.1 - 1.6e-06 27.7 0.0 0.04 13.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EPE27330.1 - 1.6e-06 28.1 0.0 0.034 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPE27330.1 - 2e-06 28.1 0.2 0.063 13.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain Cytidylate_kin2 PF13189.1 EPE27330.1 - 1.8e-05 24.7 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 Cytidylate kinase-like family ABC_tran PF00005.22 EPE27330.1 - 2.9e-05 24.3 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.21 EPE27330.1 - 4e-05 23.1 0.0 0.15 11.5 0.0 3.4 3 1 0 3 3 3 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EPE27330.1 - 4e-05 23.6 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EPE27330.1 - 7.3e-05 22.5 0.4 0.71 9.5 0.0 3.8 3 2 0 3 3 2 2 Archaeal ATPase SKI PF01202.17 EPE27330.1 - 0.00017 21.5 0.0 0.97 9.2 0.0 2.9 3 0 0 3 3 2 2 Shikimate kinase Rad17 PF03215.10 EPE27330.1 - 0.00019 20.2 0.0 0.19 10.3 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein ATP-synt_ab PF00006.20 EPE27330.1 - 0.00021 20.8 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 EPE27330.1 - 0.00036 20.1 0.0 0.29 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EPE27330.1 - 0.00042 19.2 0.0 0.27 10.0 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.8 EPE27330.1 - 0.00047 19.1 0.0 0.019 13.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EPE27330.1 - 0.00062 19.0 0.1 1.1 8.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AFG1_ATPase PF03969.11 EPE27330.1 - 0.0012 17.7 0.0 0.4 9.4 0.0 2.6 2 1 0 2 2 2 1 AFG1-like ATPase ResIII PF04851.10 EPE27330.1 - 0.0016 18.2 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EPE27330.1 - 0.0019 17.8 0.2 2.1 7.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.12 EPE27330.1 - 0.0021 16.9 0.1 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EPE27330.1 - 0.0047 16.5 0.9 3 7.4 0.0 2.8 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EPE27330.1 - 0.012 15.2 0.2 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EPE27330.1 - 0.016 14.9 0.6 1.9 8.1 0.0 3.3 3 0 0 3 3 3 0 NTPase DUF2075 PF09848.4 EPE27330.1 - 0.031 13.2 0.0 4 6.2 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 EPE27330.1 - 0.033 13.8 0.0 2.5 7.6 0.0 3.0 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein T2SE PF00437.15 EPE27330.1 - 0.045 12.6 0.0 4.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein KTI12 PF08433.5 EPE27330.1 - 0.049 12.8 0.2 44 3.1 0.0 3.2 3 0 0 3 3 3 0 Chromatin associated protein KTI12 SRPRB PF09439.5 EPE27330.1 - 0.075 12.2 0.1 9.8 5.3 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 EPE27330.1 - 0.097 12.9 1.3 4.4 7.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain DAP3 PF10236.4 EPE27330.1 - 0.1 11.4 0.0 23 3.8 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_10 PF12846.2 EPE27330.1 - 0.14 11.5 0.8 34 3.7 0.0 3.8 4 0 0 4 4 4 0 AAA-like domain Bac_DnaA PF00308.13 EPE27330.1 - 0.16 11.5 0.0 2.8 7.5 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein DUF2293 PF10056.4 EPE27331.1 - 1.7e-28 98.4 1.8 3.9e-28 97.2 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2293) Mito_carr PF00153.22 EPE27332.1 - 1.5e-44 149.6 8.4 5.1e-18 64.5 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DmpG_comm PF07836.6 EPE27332.1 - 0.084 12.2 0.0 0.26 10.7 0.0 1.8 1 0 0 1 1 1 0 DmpG-like communication domain Complex1_LYR PF05347.10 EPE27333.1 - 3.4e-06 26.7 0.7 7.6e-06 25.6 0.1 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPE27333.1 - 0.022 14.9 0.6 0.064 13.4 0.1 1.9 2 0 0 2 2 2 0 Complex1_LYR-like zinc_ribbon_6 PF14599.1 EPE27334.1 - 1.5e-25 88.7 0.9 1.5e-25 88.7 0.6 3.8 3 1 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.7 EPE27334.1 - 5.3e-16 58.5 19.2 5.3e-16 58.5 13.3 4.3 4 0 0 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 EPE27334.1 - 4.5e-08 32.7 11.1 4.5e-08 32.7 7.7 5.0 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE27334.1 - 2.2e-06 27.5 8.8 2.2e-06 27.5 6.1 5.9 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE27334.1 - 1.1e-05 24.9 8.6 1.1e-05 24.9 6.0 5.8 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE27334.1 - 3.9e-05 23.2 8.6 3.9e-05 23.2 6.0 6.0 3 2 1 4 4 4 1 zinc-RING finger domain DUF2722 PF10846.3 EPE27334.1 - 0.043 12.8 3.3 0.1 11.5 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2722) SOG2 PF10428.4 EPE27334.1 - 0.36 9.4 3.4 0.53 8.8 2.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Translin PF01997.11 EPE27335.1 - 1.3e-51 175.1 0.0 1.5e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Translin family Phage_int_SAM_1 PF02899.12 EPE27335.1 - 0.024 14.8 0.3 4.4 7.5 0.1 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain PqqD PF05402.7 EPE27335.1 - 0.039 13.9 1.2 0.078 13.0 0.1 2.0 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) BLOC1_2 PF10046.4 EPE27335.1 - 0.14 12.3 0.8 3.9 7.6 0.0 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Peroxidase_2 PF01328.12 EPE27336.1 - 1.7e-57 194.4 0.0 2.3e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 SCP2 PF02036.12 EPE27338.1 - 8.9e-25 86.9 0.4 1.1e-24 86.6 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EPE27338.1 - 3.8e-05 23.6 0.2 6.6e-05 22.8 0.2 1.4 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Rb_C PF08934.5 EPE27338.1 - 0.076 12.6 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Rb C-terminal domain SCP2_2 PF13530.1 EPE27338.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain Ran_BP1 PF00638.13 EPE27339.1 - 1.5e-13 50.8 0.1 4.5e-13 49.3 0.1 1.9 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EPE27339.1 - 0.0012 19.0 25.5 0.0012 19.0 17.7 13.7 5 3 8 13 13 13 8 Nucleoporin FG repeat region DUF287 PF03384.9 EPE27339.1 - 0.95 9.6 9.3 6.4 7.0 0.9 2.4 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 GCOM2 PF15328.1 EPE27340.1 - 0.0038 16.9 5.0 0.0046 16.7 3.4 1.2 1 0 0 1 1 1 1 Putative GRINL1B complex locus protein 2 CDC45 PF02724.9 EPE27340.1 - 0.01 13.9 6.6 0.012 13.6 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.7 EPE27340.1 - 0.038 12.3 10.9 0.044 12.1 7.5 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.7 EPE27340.1 - 0.077 10.9 7.1 0.083 10.8 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 EPE27340.1 - 0.69 7.5 3.2 0.81 7.2 2.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRN3 PF05327.6 EPE27340.1 - 3.4 5.6 6.5 3.6 5.5 4.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FTA4 PF13093.1 EPE27344.1 - 1.9e-47 161.4 0.0 2.2e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4047 PF13256.1 EPE27344.1 - 0.14 12.1 2.2 1.7 8.6 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4047) Sugar_tr PF00083.19 EPE27345.1 - 1.1e-60 205.5 28.6 1.3e-60 205.2 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE27345.1 - 2e-13 49.7 52.4 8.3e-11 41.1 11.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Hexapep PF00132.19 EPE27346.1 - 6.1e-10 38.1 19.0 1.5e-05 24.2 0.8 4.4 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 EPE27346.1 - 0.098 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.1 EPE27346.1 - 6.7 6.3 14.1 0.091 12.3 2.5 3.0 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase F-box-like PF12937.2 EPE27347.1 - 2.8e-08 33.3 0.0 1.3e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPE27347.1 - 0.027 14.1 4.0 0.034 13.8 1.2 2.4 2 1 0 2 2 2 0 F-box domain LIM PF00412.17 EPE27349.1 - 4.8e-24 84.1 19.3 1.3e-12 47.5 3.6 2.3 2 0 0 2 2 2 2 LIM domain NAD_binding_5 PF07994.7 EPE27350.1 - 5e-111 370.9 0.1 5.9e-111 370.6 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EPE27350.1 - 4.8e-46 155.1 0.2 1.8e-45 153.3 0.1 2.0 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase tRNA_anti-codon PF01336.20 EPE27351.1 - 0.0094 15.7 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain DUF3773 PF12608.3 EPE27351.1 - 0.032 14.2 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3773) Metallophos_2 PF12850.2 EPE27352.1 - 1.9e-13 50.5 0.0 2.4e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Catalase PF00199.14 EPE27353.1 - 2.5e-147 490.5 0.6 3.5e-147 490.0 0.1 1.4 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.7 EPE27353.1 - 4.8e-10 39.1 0.0 9.2e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive NmrA PF05368.8 EPE27354.1 - 1.1e-07 31.3 0.0 2.4e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EPE27354.1 - 0.00023 21.2 0.1 0.00061 19.8 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding PAC2 PF09754.4 EPE27354.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.6 2 0 0 2 2 2 0 PAC2 family Hemerythrin PF01814.18 EPE27355.1 - 1.7e-14 54.1 1.3 2.3e-14 53.6 0.9 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain NAAA-beta PF15508.1 EPE27355.1 - 0.12 12.7 0.4 1.1 9.6 0.1 2.2 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase GFA PF04828.9 EPE27356.1 - 8.8e-12 44.8 0.0 1.1e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme KGG PF10685.4 EPE27357.1 - 7e-26 89.5 9.0 6.4e-10 38.7 0.4 3.6 4 0 0 4 4 4 3 Stress-induced bacterial acidophilic repeat motif CpcD PF01383.16 EPE27357.1 - 0.084 13.0 0.1 88 3.3 0.0 3.2 3 0 0 3 3 3 0 CpcD/allophycocyanin linker domain Lectin_N PF03954.9 EPE27357.1 - 0.099 12.0 1.3 30 3.9 0.0 3.0 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain M_domain PF12938.2 EPE27357.1 - 1.2 8.8 13.2 1.6 8.4 9.1 1.2 1 0 0 1 1 1 0 M domain of GW182 DUF3534 PF12053.3 EPE27357.1 - 3.2 7.6 7.0 10 6.0 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3534) DUF1183 PF06682.7 EPE27357.1 - 7.7 6.0 19.3 3 7.3 4.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) Hemagglutinin PF00509.13 EPE27360.1 - 0.0057 14.8 0.2 0.0084 14.3 0.2 1.2 1 0 0 1 1 1 1 Haemagglutinin DUF1664 PF07889.7 EPE27360.1 - 0.29 10.9 2.5 1.3 8.8 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Lectin_N PF03954.9 EPE27360.1 - 0.75 9.1 5.0 0.42 10.0 1.4 2.1 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain CDO_I PF05995.7 EPE27364.1 - 3e-35 120.9 0.0 3.7e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EPE27364.1 - 0.00074 18.9 0.4 0.003 16.9 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) Abhydrolase_6 PF12697.2 EPE27367.1 - 8.7e-14 51.9 0.2 1.5e-13 51.2 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE27367.1 - 0.029 13.9 0.0 0.32 10.5 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold MFS_1 PF07690.11 EPE27368.1 - 1.7e-25 89.5 26.3 1.7e-25 89.5 18.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE27368.1 - 2.4e-10 39.6 3.3 2.4e-10 39.6 2.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter UNC-93 PF05978.11 EPE27368.1 - 0.0038 16.7 1.0 0.0038 16.7 0.7 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EPE27369.1 - 1.7e-93 313.6 17.5 2e-93 313.4 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE27369.1 - 9.4e-37 126.5 35.8 3e-32 111.7 13.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4538 PF15061.1 EPE27369.1 - 1.1 8.6 6.4 9 5.6 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Peptidase_C1_2 PF03051.10 EPE27370.1 - 3.7e-153 510.1 0.0 4.3e-153 509.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EPE27370.1 - 1.3e-06 28.4 0.0 0.0075 16.1 0.1 2.5 2 0 0 2 2 2 2 Papain family cysteine protease Choline_sulf_C PF12411.3 EPE27370.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal Y_phosphatase3 PF13350.1 EPE27371.1 - 1.5e-33 116.3 0.0 2.2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EPE27371.1 - 9.4e-11 41.6 1.1 1.6e-10 40.9 0.3 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EPE27371.1 - 0.003 16.9 0.0 0.0039 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EPE27371.1 - 0.038 13.3 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family FAD_binding_3 PF01494.14 EPE27372.1 - 1.2e-65 221.8 0.0 1.6e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EPE27372.1 - 7.9e-51 172.0 0.0 1.4e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain PKD PF00801.15 EPE27372.1 - 0.065 12.9 0.1 10 5.9 0.0 2.5 2 0 0 2 2 2 0 PKD domain SE PF08491.5 EPE27372.1 - 0.1 11.3 0.0 0.31 9.8 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase PSI_PsaE PF02427.12 EPE27372.1 - 0.13 11.6 0.2 21 4.5 0.1 2.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE RNase_T PF00929.19 EPE27374.1 - 0.023 14.9 0.0 0.027 14.7 0.0 1.1 1 0 0 1 1 1 0 Exonuclease Asparaginase_2 PF01112.13 EPE27375.1 - 9.2e-78 261.1 0.0 1.1e-77 260.8 0.0 1.0 1 0 0 1 1 1 1 Asparaginase Peptidase_M43 PF05572.8 EPE27376.1 - 1.4e-14 53.9 0.0 2.9e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EPE27376.1 - 4.2e-08 33.3 0.0 7.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EPE27376.1 - 6.6e-06 26.6 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EPE27376.1 - 2.2e-05 24.5 0.1 4.1e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EPE27376.1 - 0.0038 16.7 0.5 0.0072 15.8 0.3 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EPE27376.1 - 0.019 13.8 0.2 0.029 13.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.3 EPE27376.1 - 0.067 11.6 0.6 0.098 11.0 0.4 1.2 1 0 0 1 1 1 0 Putative peptidase family adh_short PF00106.20 EPE27377.1 - 3.2e-16 59.6 0.0 8.4e-16 58.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE27377.1 - 2e-07 30.8 0.0 3.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE27377.1 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPE27377.1 - 7.4e-05 21.7 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Clr5 PF14420.1 EPE27378.1 - 4.5e-11 42.4 5.7 1.4e-10 40.8 3.9 1.9 1 0 0 1 1 1 1 Clr5 domain FabA PF07977.8 EPE27378.1 - 0.029 13.8 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 FabA-like domain zf-C2H2_4 PF13894.1 EPE27378.1 - 0.22 11.9 14.6 5.9 7.4 0.4 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE27378.1 - 2.1 8.8 11.9 8.2 6.9 0.3 4.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF605 PF04652.11 EPE27380.1 - 0.75 9.1 26.8 0.95 8.7 18.6 1.1 1 0 0 1 1 1 0 Vta1 like SNase PF00565.12 EPE27383.1 - 9.6e-71 234.9 0.9 5.7e-23 81.2 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EPE27383.1 - 3.3e-23 81.8 0.0 7e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 EPE27383.1 - 4e-05 22.8 1.3 0.00014 21.1 0.0 2.2 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) DUF3560 PF12083.3 EPE27383.1 - 2.2 8.3 9.9 19 5.3 1.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3560) Sod_Cu PF00080.15 EPE27384.1 - 3e-43 147.3 5.7 4e-43 146.9 3.9 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MR_MLE_C PF13378.1 EPE27385.1 - 8.2e-21 74.0 0.0 1.5e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EPE27385.1 - 2.1e-12 47.3 0.0 6.2e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EPE27385.1 - 1.1e-09 38.2 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short PF00106.20 EPE27386.1 - 9e-28 97.2 2.0 1.3e-27 96.7 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE27386.1 - 3.1e-21 76.2 0.0 3.8e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE27386.1 - 3.4e-10 39.8 1.0 4.8e-10 39.3 0.7 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EPE27386.1 - 2.5e-05 23.3 0.0 3.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EPE27386.1 - 0.014 15.3 0.2 0.023 14.6 0.2 1.3 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPE27386.1 - 0.11 11.4 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RTA1 PF04479.8 EPE27388.1 - 8e-46 156.3 16.1 1.4e-45 155.5 11.1 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF3188 PF11384.3 EPE27388.1 - 0.12 11.9 3.3 2.5 7.7 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3188) LHC PF00556.15 EPE27388.1 - 2.7 7.9 10.8 0.31 10.9 0.8 3.1 2 1 1 3 3 3 0 Antenna complex alpha/beta subunit YrhK PF14145.1 EPE27388.1 - 3.6 7.3 13.2 4.3 7.0 0.2 4.0 4 0 0 4 4 4 0 YrhK-like protein RNase_H PF00075.19 EPE27391.1 - 3.6e-07 30.5 0.0 4.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EPE27391.1 - 0.15 11.8 0.1 0.76 9.5 0.0 2.1 2 1 0 2 2 2 0 Reverse transcriptase-like DAO PF01266.19 EPE27392.1 - 1.8e-50 171.8 0.1 2.2e-50 171.5 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE27392.1 - 1.1e-05 24.4 0.5 0.00011 21.1 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EPE27392.1 - 0.00012 22.2 0.0 0.57 10.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE27392.1 - 0.00027 20.1 0.0 0.00078 18.6 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EPE27392.1 - 0.0042 17.0 0.0 0.0096 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE27392.1 - 0.0079 15.1 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DUF258 PF03193.11 EPE27392.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NAD_binding_9 PF13454.1 EPE27392.1 - 0.063 13.0 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPE27392.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase OPT PF03169.10 EPE27393.1 - 3e-179 597.4 60.1 3.5e-179 597.2 41.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2953 PF11167.3 EPE27393.1 - 0.003 17.4 0.2 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2953) DUF4191 PF13829.1 EPE27393.1 - 0.12 11.5 2.2 0.45 9.5 1.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) CcmD PF04995.9 EPE27393.1 - 7.5 6.3 8.4 0.49 10.1 1.2 2.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Memo PF01875.12 EPE27394.1 - 2.5e-72 243.0 0.0 2.8e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Fungal_trans_2 PF11951.3 EPE27395.1 - 0.0001 21.0 3.0 0.0031 16.1 0.0 2.8 2 1 1 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27395.1 - 0.0065 16.3 2.8 0.01 15.7 2.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3 PF00933.16 EPE27396.1 - 1.1e-82 277.4 0.0 1.5e-82 276.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE27396.1 - 1.5e-52 178.3 0.1 1.1e-51 175.5 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE27396.1 - 2.1e-22 78.8 0.2 3.8e-22 78.0 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Mito_carr PF00153.22 EPE27396.1 - 0.083 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial carrier protein UPF0184 PF03670.8 EPE27397.1 - 0.12 12.5 0.3 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Atg14 PF10186.4 EPE27398.1 - 0.0048 15.8 2.4 0.0098 14.8 1.6 1.6 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 COG2 PF06148.6 EPE27398.1 - 0.0091 15.8 6.6 0.96 9.3 0.2 3.3 2 1 2 4 4 4 2 COG (conserved oligomeric Golgi) complex component, COG2 Filament PF00038.16 EPE27398.1 - 0.011 15.2 1.7 0.04 13.4 1.0 1.9 2 0 0 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 EPE27398.1 - 2 8.1 9.6 0.24 11.1 2.6 2.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Lipoprotein_15 PF03640.10 EPE27399.1 - 0.059 12.8 0.2 0.18 11.2 0.1 1.8 1 0 0 1 1 1 0 Secreted repeat of unknown function Pkinase PF00069.20 EPE27400.1 - 1.1e-08 34.5 0.0 1.5e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE27400.1 - 0.0049 15.9 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EPE27400.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EPE27400.1 - 0.02 13.9 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE27400.1 - 0.024 14.3 0.6 0.034 13.8 0.4 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3425 PF11905.3 EPE27401.1 - 3.7e-32 111.0 0.4 6.7e-32 110.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) HTH_Tnp_Tc5 PF03221.11 EPE27401.1 - 1.5e-13 50.2 0.5 5.9e-13 48.4 0.4 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain adh_short PF00106.20 EPE27402.1 - 2.5e-14 53.5 0.1 4.5e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE27402.1 - 0.00033 20.5 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE27402.1 - 0.0062 16.2 0.1 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EPE27402.1 - 0.13 11.6 0.8 0.32 10.4 0.5 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 EPE27403.1 - 4.4e-15 55.2 19.1 8e-15 54.4 13.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.11 EPE27404.1 - 5.5e-40 137.6 0.0 7.1e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Syja_N PF02383.13 EPE27405.1 - 3.7e-94 315.0 0.1 4.7e-94 314.7 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.17 EPE27406.1 - 3.7e-59 198.7 0.4 4.2e-59 198.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE27406.1 - 3.3e-19 69.5 0.1 7.9e-19 68.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPE27406.1 - 8.2e-16 57.7 0.1 1e-15 57.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPE27406.1 - 1.1e-08 34.4 0.0 1.4e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPE27406.1 - 4.3e-08 32.8 0.0 6.1e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPE27406.1 - 7.6e-06 25.8 0.0 1.1e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EPE27406.1 - 0.015 15.4 0.1 2 8.5 0.0 2.5 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 EPE27406.1 - 0.041 13.0 0.4 0.19 10.9 0.0 2.1 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EPE27406.1 - 0.1 12.5 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain TCP PF03634.8 EPE27406.1 - 0.11 12.9 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 TCP family transcription factor G-alpha PF00503.15 EPE27406.1 - 0.11 11.1 0.3 6.7 5.2 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 EPE27406.1 - 0.14 12.1 0.4 0.36 10.7 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain Mitofilin PF09731.4 EPE27407.1 - 1.9e-159 532.0 17.7 2.2e-159 531.8 12.3 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Myco_arth_vir_N PF09610.5 EPE27407.1 - 0.48 10.4 2.7 1.1 9.3 1.9 1.6 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) PhyH PF05721.8 EPE27408.1 - 6.6e-10 39.3 0.1 2e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EPE27408.1 - 1.5e-06 27.0 0.1 0.0079 14.7 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) Fungal_trans PF04082.13 EPE27409.1 - 8.9e-22 77.2 0.1 1.3e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EPE27410.1 - 1.2e-96 324.0 23.8 1.4e-96 323.8 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE27410.1 - 3.8e-13 48.9 20.2 3.8e-13 48.9 14.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3029 PF11230.3 EPE27413.1 - 0.018 13.2 0.1 0.023 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) MutS_V PF00488.16 EPE27414.1 - 5.4e-80 268.1 0.1 8.1e-80 267.5 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPE27414.1 - 7.2e-48 163.0 0.0 1.2e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EPE27414.1 - 6e-33 113.2 0.0 2.6e-32 111.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EPE27414.1 - 5.4e-14 52.1 0.0 1.3e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EPE27414.1 - 3.6e-10 40.0 0.0 1.3e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 EPE27414.1 - 0.01 16.1 1.8 0.018 15.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EPE27414.1 - 0.021 14.3 0.0 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EPE27414.1 - 0.053 13.4 1.4 0.082 12.8 0.2 1.9 2 0 0 2 2 2 0 AAA domain Abhydrolase_2 PF02230.11 EPE27415.1 - 1.1e-19 70.7 0.3 2.8e-11 43.3 0.1 3.1 2 1 1 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EPE27415.1 - 4e-06 26.6 0.1 9e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPE27415.1 - 6.7e-05 22.4 0.0 0.0001 21.8 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EPE27415.1 - 0.00014 21.2 0.0 0.00026 20.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EPE27415.1 - 0.00024 21.0 0.5 0.0069 16.2 0.1 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Raffinose_syn PF05691.7 EPE27416.1 - 1.8e-53 181.2 3.1 4.2e-46 156.8 0.0 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EPE27416.1 - 1.4e-05 23.9 0.2 2.7e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Melibiase ocr PF08684.5 EPE27416.1 - 0.00014 21.8 0.1 0.00033 20.6 0.1 1.6 1 0 0 1 1 1 1 DNA mimic ocr tRNA-synt_1b PF00579.20 EPE27417.1 - 4.1e-74 249.3 0.0 5.4e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EPE27417.1 - 0.054 12.9 0.1 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 S4 domain CD34_antigen PF06365.7 EPE27418.1 - 0.005 16.5 0.6 0.0084 15.7 0.4 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Sensor PF13796.1 EPE27418.1 - 0.18 11.4 2.2 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 Putative sensor Adeno_E3_CR2 PF02439.10 EPE27418.1 - 5.2 6.6 7.0 12 5.5 4.8 1.6 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 Peptidase_M28 PF04389.12 EPE27419.1 - 1.7e-36 125.5 0.1 2.3e-36 125.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M28 DUF3328 PF11807.3 EPE27422.1 - 1.7e-56 191.3 0.0 2.1e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.3 EPE27424.1 - 3e-15 55.7 1.4 2.9e-14 52.4 0.6 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27424.1 - 5.7e-05 22.9 8.7 0.00011 22.0 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_N PF00752.12 EPE27425.1 - 9.9e-35 118.8 0.0 2.7e-34 117.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EPE27425.1 - 2.9e-26 91.3 0.0 6.9e-26 90.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EPE27425.1 - 0.0065 15.9 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EPE27425.1 - 0.033 14.4 0.0 0.14 12.3 0.0 2.2 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.15 EPE27425.1 - 0.28 10.8 11.3 0.55 9.9 1.5 3.8 3 0 0 3 3 3 0 Ubiquitin interaction motif NAD_binding_10 PF13460.1 EPE27426.1 - 2.7e-09 37.3 0.0 4.9e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE27426.1 - 0.0031 16.7 0.0 0.0061 15.8 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family DUF1996 PF09362.5 EPE27427.1 - 6.1e-79 264.9 4.5 8.3e-79 264.5 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) adh_short PF00106.20 EPE27427.1 - 2.3e-17 63.4 0.0 7.3e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE27427.1 - 1e-09 38.5 0.0 1.8e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EPE27427.1 - 0.045 12.8 0.0 0.99 8.4 0.0 2.1 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EPE27427.1 - 0.048 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding ZZ PF00569.12 EPE27428.1 - 2.8e-11 42.7 8.1 5e-11 41.9 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 EPE27428.1 - 4.8e-11 41.1 3.8 9.8e-05 21.3 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EPE27428.1 - 3e-08 33.6 0.4 0.011 15.8 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 EPE27428.1 - 1.5e-06 27.7 0.2 0.063 12.9 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EPE27428.1 - 4.5e-06 26.0 2.0 0.0069 16.1 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain Asp PF00026.18 EPE27429.1 - 2.2e-64 217.7 3.8 2.9e-64 217.3 2.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPE27429.1 - 5.5e-08 32.9 1.6 2.3e-06 27.6 0.0 3.5 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EPE27429.1 - 0.00013 21.5 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EPE27429.1 - 0.73 10.3 10.4 6.8 7.2 0.0 4.7 6 0 0 6 6 6 0 Aspartyl protease Fungal_trans_2 PF11951.3 EPE27430.1 - 2.7e-07 29.5 0.0 0.013 14.1 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Atg31 PF09795.4 EPE27431.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 31 DUF605 PF04652.11 EPE27431.1 - 4.6 6.5 12.7 5.6 6.2 8.8 1.1 1 0 0 1 1 1 0 Vta1 like HAD_2 PF13419.1 EPE27433.1 - 4.2e-31 108.5 0.1 6.5e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE27433.1 - 2.2e-08 33.6 0.1 3.5e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EPE27433.1 - 2.8e-06 27.8 0.1 2.6e-05 24.7 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2353 PF09789.4 EPE27434.1 - 0.0035 16.6 2.2 0.0064 15.7 1.5 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) MutS_IV PF05190.13 EPE27434.1 - 0.027 14.6 0.2 0.067 13.3 0.1 1.6 1 0 0 1 1 1 0 MutS family domain IV PRANC PF09372.5 EPE27434.1 - 0.047 13.6 1.6 0.12 12.4 1.1 1.6 1 0 0 1 1 1 0 PRANC domain Med10 PF09748.4 EPE27434.1 - 0.048 13.4 1.0 0.11 12.3 0.2 2.0 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex BLOC1_2 PF10046.4 EPE27434.1 - 0.081 13.0 2.3 0.19 11.9 1.6 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rootletin PF15035.1 EPE27434.1 - 1.2 9.1 11.1 0.088 12.7 4.5 1.4 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Myb_DNA-bind_4 PF13837.1 EPE27434.1 - 2.8 8.1 9.1 0.74 9.9 0.8 3.0 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain TMF_DNA_bd PF12329.3 EPE27434.1 - 9 6.1 8.5 0.65 9.8 1.9 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc7_N PF15402.1 EPE27435.1 - 0 1085.0 76.0 1.1e-176 589.6 24.5 2.1 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EPE27435.1 - 1.4e-114 382.1 2.2 2.8e-114 381.1 1.5 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EPE27435.1 - 1.2e-17 63.3 0.8 2.3e-17 62.4 0.6 1.5 1 0 0 1 1 1 1 Spc7_C2 Ribosomal_S17 PF00366.15 EPE27436.1 - 5.4e-30 103.2 0.7 7.7e-30 102.7 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 DUF4642 PF15484.1 EPE27437.1 - 0.039 13.9 3.7 0.046 13.7 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) DUF809 PF05663.6 EPE27437.1 - 2.4 8.1 5.8 3.1 7.7 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Glyco_hydro_61 PF03443.9 EPE27438.1 - 3e-67 226.6 0.1 5e-67 225.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EPE27438.1 - 6.2e-10 38.5 5.7 2.2e-09 36.7 3.9 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain p450 PF00067.17 EPE27439.1 - 1e-28 100.1 0.0 1.4e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.9 EPE27440.1 - 2e-101 338.8 0.2 3.4e-101 338.1 0.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EPE27440.1 - 0.028 13.7 0.1 0.049 12.9 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Tetraspannin PF00335.15 EPE27441.1 - 0.0063 15.8 0.7 2.2 7.4 0.1 2.2 2 0 0 2 2 2 2 Tetraspanin family DUF2668 PF10873.3 EPE27441.1 - 0.024 14.8 0.3 0.064 13.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) DUF2976 PF11190.3 EPE27441.1 - 0.065 12.7 0.5 5.5 6.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) HET PF06985.6 EPE27442.1 - 9.7e-21 74.3 0.0 1.9e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EPE27443.1 - 1.1e-28 100.0 0.0 5.7e-28 97.8 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 EPE27444.1 - 1.3e-18 67.5 0.0 2.1e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE27444.1 - 0.00038 21.2 0.0 0.0054 17.5 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 EPE27444.1 - 0.0035 17.4 0.1 0.018 15.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EPE27444.1 - 0.0072 15.4 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPE27444.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zot PF05707.7 EPE27444.1 - 0.019 14.4 0.0 0.26 10.7 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_16 PF13191.1 EPE27444.1 - 0.024 14.6 0.0 0.077 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EPE27444.1 - 0.025 13.6 0.0 0.65 9.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 EPE27444.1 - 0.036 13.6 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPE27444.1 - 0.044 14.0 0.0 0.26 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 EPE27444.1 - 0.06 13.2 0.0 0.74 9.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EPE27444.1 - 0.067 12.9 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EPE27444.1 - 0.15 11.1 0.1 0.36 9.8 0.1 1.6 1 0 0 1 1 1 0 KaiC ApbA_C PF08546.6 EPE27446.1 - 8e-29 100.1 0.1 3.3e-28 98.1 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EPE27446.1 - 9.7e-28 96.5 0.0 1.3e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 EPE27446.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding Fungal_trans_2 PF11951.3 EPE27447.1 - 1.2e-38 132.7 0.7 1.6e-38 132.3 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27447.1 - 4.6e-07 29.6 6.6 1.2e-06 28.3 4.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Isochorismatase PF00857.15 EPE27448.1 - 1.3e-21 77.3 0.0 1.9e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Mur_ligase_M PF08245.7 EPE27451.1 - 3.4e-05 23.9 0.0 0.0002 21.4 0.0 2.2 1 1 0 1 1 1 1 Mur ligase middle domain Vg_Tdu PF07545.9 EPE27451.1 - 0.12 11.8 0.3 0.33 10.4 0.2 1.7 1 0 0 1 1 1 0 Vestigial/Tondu family MFS_1 PF07690.11 EPE27452.1 - 9.5e-28 96.9 46.0 9.5e-28 96.9 31.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Dispanin PF04505.7 EPE27452.1 - 0.0021 17.5 0.3 0.33 10.5 0.0 2.9 2 0 0 2 2 2 2 Interferon-induced transmembrane protein p450 PF00067.17 EPE27453.1 - 2.3e-37 128.6 0.0 3e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 EPE27454.1 - 3.6e-79 265.8 0.2 4.5e-78 262.2 0.1 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EPE27454.1 - 1.7e-36 124.6 0.3 5.4e-36 123.0 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EPE27454.1 - 9.1e-23 81.0 0.0 1.6e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.7 EPE27454.1 - 6.3e-17 61.8 0.0 1.7e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 EPE27454.1 - 2e-14 53.6 0.0 2.1e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold PP-binding PF00550.20 EPE27454.1 - 5.8e-13 48.9 0.2 4.8e-12 45.9 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EPE27454.1 - 2.2e-09 37.2 0.0 2.8e-08 33.6 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 EPE27454.1 - 2.4e-09 36.9 0.0 6.4e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE27454.1 - 2.9e-09 36.8 0.0 5.9e-08 32.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_6 PF12697.2 EPE27454.1 - 4.6e-08 33.2 4.5 1.8e-06 27.9 2.1 3.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Methyltransf_18 PF12847.2 EPE27454.1 - 2.7e-07 31.1 0.0 4.4e-06 27.2 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE27454.1 - 3e-07 30.8 0.0 9.2e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 EPE27454.1 - 4.7e-06 25.9 0.1 0.0037 16.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Methyltransf_16 PF10294.4 EPE27454.1 - 5.8e-05 22.6 0.0 0.00083 18.8 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Thiolase_N PF00108.18 EPE27454.1 - 0.00011 21.2 0.1 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DLH PF01738.13 EPE27454.1 - 0.0002 20.6 0.0 0.093 11.9 0.0 2.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Methyltransf_26 PF13659.1 EPE27454.1 - 0.0037 17.2 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE27454.1 - 0.0065 15.8 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain AXE1 PF05448.7 EPE27454.1 - 0.057 11.9 0.0 0.11 10.9 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) ACP_syn_III PF08545.5 EPE27454.1 - 0.1 12.2 2.7 9.4 5.9 0.0 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.17 EPE27455.1 - 2.8e-56 191.0 0.0 3.3e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YtxC PF08812.6 EPE27455.1 - 0.043 13.3 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 YtxC-like family Methyltransf_25 PF13649.1 EPE27456.1 - 1.8e-08 34.6 0.0 4.1e-08 33.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE27456.1 - 4.1e-06 27.1 0.0 7.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE27456.1 - 1.5e-05 24.7 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE27456.1 - 0.00055 20.3 0.0 0.00092 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE27456.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GMC_oxred_N PF00732.14 EPE27458.1 - 1.8e-50 171.7 0.2 2.9e-50 171.1 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE27458.1 - 2.9e-33 115.1 0.4 6.2e-33 114.1 0.1 1.8 2 0 0 2 2 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EPE27458.1 - 4.8e-07 28.9 1.6 0.0019 17.1 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EPE27458.1 - 1.5e-05 25.1 0.8 0.086 12.8 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE27458.1 - 2.9e-05 23.9 0.1 0.00014 21.7 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE27458.1 - 5e-05 22.3 0.2 0.00012 21.1 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE27458.1 - 9.6e-05 21.4 0.5 0.00046 19.2 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPE27458.1 - 0.0061 16.4 0.4 0.015 15.1 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE27458.1 - 0.0074 15.4 0.2 0.018 14.1 0.1 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EPE27458.1 - 0.03 12.7 0.1 0.048 12.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EPE27458.1 - 0.039 13.7 0.3 0.098 12.4 0.2 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EPE27458.1 - 0.068 11.7 1.4 0.11 11.1 1.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 EPE27458.1 - 0.11 12.5 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain PhyH PF05721.8 EPE27459.1 - 1.6e-13 51.1 0.0 2.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 EPE27459.1 - 0.0022 18.4 0.0 0.0044 17.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 EPE27459.1 - 0.023 14.9 0.0 1.4 9.2 0.0 2.9 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase Trp_DMAT PF11991.3 EPE27460.1 - 4.6e-48 164.2 0.0 5.9e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF3328 PF11807.3 EPE27461.1 - 2.1e-22 79.8 0.4 2.9e-22 79.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EPE27462.1 - 1.4e-23 83.2 18.4 1.3e-21 76.7 1.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EPE27463.1 - 8.2e-42 143.2 0.0 9.9e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 EPE27464.1 - 2.4e-09 36.8 0.0 3.1e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE27464.1 - 3.1e-08 33.8 0.0 5.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EPE27464.1 - 0.0062 16.2 0.0 2.5 7.7 0.0 3.0 2 1 0 3 3 3 1 KR domain Polysacc_deac_2 PF04748.8 EPE27464.1 - 0.0082 15.1 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase Methyltransf_2 PF00891.13 EPE27465.1 - 4e-32 111.3 0.0 5.7e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EPE27465.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain p450 PF00067.17 EPE27466.1 - 5.5e-62 209.7 0.0 7.2e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2938 PF11158.3 EPE27467.1 - 0.0041 16.4 0.1 0.0047 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2938) Myb_DNA-binding PF00249.26 EPE27468.1 - 3.8e-30 103.6 10.5 3.3e-13 49.4 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPE27468.1 - 4.3e-28 97.1 8.3 1.1e-14 54.2 0.2 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EPE27468.1 - 0.089 12.7 5.8 19 5.2 1.1 4.2 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EPE27468.1 - 0.9 9.7 3.4 2.9 8.1 0.1 2.9 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like p450 PF00067.17 EPE27469.1 - 1.9e-30 105.8 0.2 4.3e-17 61.7 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 3Beta_HSD PF01073.14 EPE27470.1 - 7.4e-58 195.4 0.0 1.4e-57 194.6 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE27470.1 - 2.8e-29 102.2 0.1 3.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPE27470.1 - 2.6e-09 36.3 0.0 3.5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPE27470.1 - 2.8e-08 34.0 0.0 4.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPE27470.1 - 2.8e-08 33.0 0.2 1.5e-06 27.2 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EPE27470.1 - 0.00017 20.9 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EPE27470.1 - 0.00026 20.0 0.1 0.00053 18.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EPE27470.1 - 0.0018 18.2 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 EPE27470.1 - 0.0039 16.8 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EPE27470.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EPE27470.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase ABC2_membrane PF01061.19 EPE27472.1 - 8e-32 110.1 22.7 8e-32 110.1 15.7 1.4 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 EPE27472.1 - 2.5e-25 88.1 1.2 5.3e-25 87.0 0.0 2.2 2 0 0 2 2 2 1 CDR ABC transporter ABC_tran PF00005.22 EPE27472.1 - 4.7e-16 59.3 0.3 8.5e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 EPE27472.1 - 0.00036 19.9 0.0 0.0011 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPE27472.1 - 0.0062 16.0 0.6 0.014 14.9 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EPE27472.1 - 0.042 13.0 0.0 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EPE27472.1 - 0.092 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.19 EPE27473.1 - 6.7e-35 120.1 28.2 6.7e-35 120.1 19.5 1.4 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 EPE27473.1 - 0.015 14.9 2.5 0.22 11.2 0.1 2.9 2 0 0 2 2 2 0 CDR ABC transporter ABC2_membrane_3 PF12698.2 EPE27473.1 - 0.019 13.9 31.9 0.013 14.5 19.4 2.5 1 1 1 2 2 2 0 ABC-2 family transporter protein SMC_N PF02463.14 EPE27473.1 - 0.069 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain IBR PF01485.16 EPE27474.1 - 8.1e-06 25.6 6.3 8.1e-06 25.6 4.4 3.8 2 2 0 3 3 3 1 IBR domain zf-C3HC4_2 PF13923.1 EPE27474.1 - 4.3e-05 23.4 5.1 4.3e-05 23.4 3.5 4.3 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE27474.1 - 0.00033 20.3 2.2 0.00033 20.3 1.5 4.3 4 1 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPE27474.1 - 0.00034 20.3 11.7 0.00034 20.3 8.1 3.7 2 1 1 3 3 3 1 Ring finger domain zf-RING_4 PF14570.1 EPE27474.1 - 7.7 6.1 21.7 31 4.2 2.4 4.7 4 1 0 4 4 4 0 RING/Ubox like zinc-binding domain Mur_ligase_M PF08245.7 EPE27475.1 - 1.2e-05 25.4 0.5 0.00017 21.7 0.1 2.8 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EPE27475.1 - 0.0013 18.6 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 EPE27476.1 - 7.9e-05 22.7 0.0 0.073 13.1 0.0 2.9 2 1 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.16 EPE27476.1 - 0.034 14.1 0.0 0.095 12.7 0.0 1.8 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain CorA PF01544.13 EPE27477.1 - 1.5e-07 30.7 0.0 2.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein WD40 PF00400.27 EPE27479.1 - 1.3e-27 94.5 12.6 1.8e-06 27.6 0.0 6.9 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EPE27479.1 - 1.5e-05 24.8 0.5 0.03 14.0 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 EPE27479.1 - 0.0042 16.6 0.4 0.015 14.7 0.0 2.3 2 0 0 2 2 2 1 HIRA B motif Apc4_WD40 PF12894.2 EPE27479.1 - 0.056 12.9 0.0 2.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 EPE27479.1 - 0.086 12.5 2.4 8.7 6.1 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ABC_tran PF00005.22 EPE27480.1 - 1.2e-48 164.8 0.0 1.2e-28 100.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPE27480.1 - 1.6e-22 80.1 30.9 2.9e-15 56.4 8.5 3.7 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EPE27480.1 - 1.6e-08 34.0 0.0 9.3e-05 21.7 0.0 3.7 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EPE27480.1 - 2.3e-05 23.8 0.0 0.054 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPE27480.1 - 0.00011 22.2 0.1 0.14 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 EPE27480.1 - 0.00017 20.6 0.0 0.14 11.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 EPE27480.1 - 0.00066 19.1 0.3 0.86 9.1 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPE27480.1 - 0.00087 18.5 0.0 0.6 9.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 EPE27480.1 - 0.001 18.9 0.1 0.86 9.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 EPE27480.1 - 0.0052 17.1 0.3 0.47 10.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EPE27480.1 - 0.0074 16.4 0.6 8.8 6.4 0.0 3.5 3 1 0 3 3 3 0 AAA domain Miro PF08477.8 EPE27480.1 - 0.0079 16.6 0.1 5.6 7.4 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EPE27480.1 - 0.0094 15.8 0.1 0.51 10.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.1 EPE27480.1 - 0.014 15.3 0.5 0.26 11.1 0.0 3.0 2 2 1 3 3 3 0 AAA domain AAA_10 PF12846.2 EPE27480.1 - 0.017 14.5 0.0 1.9 7.8 0.0 2.5 2 1 0 2 2 2 0 AAA-like domain DUF2075 PF09848.4 EPE27480.1 - 0.018 14.0 0.0 0.33 9.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.18 EPE27480.1 - 0.034 13.9 0.1 9.2 6.0 0.0 2.8 3 0 0 3 3 3 0 Dynamin family SbcCD_C PF13558.1 EPE27480.1 - 0.1 12.5 0.1 8.4 6.3 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Glyco_hydro_61 PF03443.9 EPE27481.1 - 1.5e-44 152.3 0.0 3.5e-44 151.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Vps52 PF04129.7 EPE27482.1 - 0.25 9.8 2.4 0.31 9.5 1.7 1.0 1 0 0 1 1 1 0 Vps52 / Sac2 family p450 PF00067.17 EPE27485.1 - 1.3e-43 149.1 0.0 2.4e-43 148.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 EPE27486.1 - 2.6e-162 540.3 0.1 3e-162 540.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EPE27486.1 - 0.22 10.7 0.0 1.5 7.9 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) DUF676 PF05057.9 EPE27487.1 - 2e-05 23.9 0.0 3.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.7 EPE27487.1 - 0.008 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 EPE27487.1 - 0.022 14.3 0.0 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein PQQ_2 PF13360.1 EPE27488.1 - 2.1e-06 27.3 0.3 0.027 13.9 0.1 3.0 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.16 EPE27488.1 - 0.015 14.8 0.0 1.3 8.7 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat MMS1_N PF10433.4 EPE27488.1 - 0.021 13.0 0.0 2.5 6.1 0.0 2.6 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EPE27488.1 - 0.17 11.8 4.3 1.1e+02 2.9 0.1 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat adh_short PF00106.20 EPE27489.1 - 2.7e-21 76.2 0.2 3.5e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE27489.1 - 1.3e-12 47.9 0.0 1.7e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE27489.1 - 1.7e-11 44.1 0.1 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE27489.1 - 1.1e-09 38.1 0.1 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE27489.1 - 8e-06 25.9 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE27489.1 - 0.00011 21.5 0.1 0.00021 20.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EPE27489.1 - 0.00032 19.7 0.0 0.00045 19.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EPE27489.1 - 0.0013 17.6 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EPE27489.1 - 0.018 13.9 0.3 0.2 10.5 0.2 2.0 1 1 0 1 1 1 0 Male sterility protein Fungal_trans PF04082.13 EPE27490.1 - 2.4e-16 59.4 1.0 2.4e-16 59.4 0.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27490.1 - 2.5e-05 24.0 13.5 2.5e-05 24.0 9.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 EPE27492.1 - 6.5e-54 179.7 19.7 2.6e-11 43.2 0.0 8.7 5 1 4 10 10 10 8 Tetratricopeptide repeat TPR_10 PF13374.1 EPE27492.1 - 1.3e-49 164.7 11.7 3.9e-09 36.1 0.1 10.9 11 0 0 11 11 10 9 Tetratricopeptide repeat NB-ARC PF00931.17 EPE27492.1 - 1.5e-11 43.7 0.0 3e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 EPE27492.1 - 3.6e-11 41.9 10.0 0.093 12.5 0.0 8.9 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPE27492.1 - 2.9e-10 40.5 3.9 7.2e-05 23.3 0.0 6.4 6 1 2 8 8 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 EPE27492.1 - 4.9e-09 35.7 8.8 0.41 11.2 0.0 7.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EPE27492.1 - 6.4e-09 35.3 9.3 0.0018 17.9 0.7 6.3 6 2 2 8 8 8 2 TPR repeat TPR_2 PF07719.12 EPE27492.1 - 1.1e-08 34.3 20.6 0.02 14.7 0.0 9.3 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPE27492.1 - 1.4e-08 33.9 13.6 0.0003 20.2 0.0 8.6 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPE27492.1 - 4.8e-06 26.8 1.4 0.005 17.1 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE27492.1 - 8.6e-05 22.8 4.8 46 5.0 0.0 7.7 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPE27492.1 - 0.00019 21.0 6.6 9.2 6.3 0.0 6.9 8 0 0 8 8 6 0 Tetratricopeptide repeat AAA_22 PF13401.1 EPE27492.1 - 0.00036 20.6 0.0 0.0015 18.6 0.0 2.0 1 1 0 2 2 2 1 AAA domain TPR_17 PF13431.1 EPE27492.1 - 0.00097 19.1 9.2 11 6.5 0.0 6.4 8 0 0 8 8 5 0 Tetratricopeptide repeat DUF429 PF04250.8 EPE27492.1 - 0.004 16.4 0.1 0.0086 15.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF429) Apc3 PF12895.2 EPE27492.1 - 0.0058 16.7 11.9 0.088 12.9 0.1 5.8 4 2 2 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EPE27492.1 - 0.0085 16.4 8.8 16 6.1 0.0 6.6 6 0 0 6 6 5 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 EPE27492.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase Methyltransf_2 PF00891.13 EPE27494.1 - 1.2e-39 135.9 0.0 1.9e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EPE27494.1 - 0.0013 19.3 0.0 0.0084 16.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain DUF2805 PF10985.3 EPE27494.1 - 0.0057 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2805) Peptidase_M48 PF01435.13 EPE27495.1 - 1.3e-07 31.4 0.0 0.0098 15.4 0.0 2.4 2 1 0 2 2 2 2 Peptidase family M48 DUF955 PF06114.8 EPE27495.1 - 9.4e-05 22.1 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF955) Peptidase_U49 PF10463.4 EPE27495.1 - 0.037 13.8 0.2 0.067 12.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase U49 adh_short PF00106.20 EPE27496.1 - 9.8e-13 48.3 0.0 2.4e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE27496.1 - 0.067 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 KR domain Fungal_trans_2 PF11951.3 EPE27497.1 - 2.1e-43 148.4 0.2 3.3e-43 147.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27497.1 - 4.4e-07 29.7 12.7 8.6e-07 28.7 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.15 EPE27498.1 - 4.7e-38 131.5 1.5 6.7e-38 131.0 1.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase CorA PF01544.13 EPE27499.1 - 0.0032 16.5 3.8 0.0035 16.4 1.3 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF4100 PF13352.1 EPE27499.1 - 0.013 14.9 0.0 0.034 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4100) PAM2 PF07145.10 EPE27499.1 - 0.018 14.5 0.5 0.073 12.6 0.3 2.1 1 0 0 1 1 1 0 Ataxin-2 C-terminal region C6_DPF PF10170.4 EPE27500.1 - 0.013 15.5 2.7 0.026 14.5 1.0 2.0 2 0 0 2 2 2 0 Cysteine-rich domain zf-UDP PF14569.1 EPE27500.1 - 0.054 13.2 0.3 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 EPE27500.1 - 0.12 12.3 4.6 0.27 11.3 3.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EPE27500.1 - 0.15 11.9 4.1 0.31 10.9 2.9 1.6 1 0 0 1 1 1 0 IBR domain FYVE_2 PF02318.11 EPE27500.1 - 0.28 11.1 6.0 0.064 13.1 1.9 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.16 EPE27500.1 - 0.37 10.7 9.4 1.6 8.6 6.5 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_3 PF13920.1 EPE27500.1 - 0.57 9.8 9.0 0.27 10.9 4.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE27500.1 - 4.1 7.2 10.3 9.7 6.0 7.1 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-B_box PF00643.19 EPE27500.1 - 4.4 7.2 9.7 0.26 11.2 0.9 2.6 3 0 0 3 3 3 0 B-box zinc finger zf-RanBP PF00641.13 EPE27500.1 - 7.4 5.7 11.7 0.1 11.7 0.8 2.9 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others HET PF06985.6 EPE27502.1 - 3.7e-34 117.8 0.0 6.3e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EPE27503.1 - 2e-17 62.9 21.5 9.6e-17 60.7 14.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_2 PF00891.13 EPE27504.1 - 2.7e-32 111.8 0.0 4.9e-32 111.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EPE27504.1 - 0.0037 17.0 0.1 0.0081 15.9 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.1 EPE27504.1 - 0.0073 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NfrA_C PF13283.1 EPE27504.1 - 0.039 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term Rrf2 PF02082.15 EPE27504.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator PEX-2N PF09263.5 EPE27504.1 - 0.14 12.5 0.1 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal DNA_pol_A_exo1 PF01612.15 EPE27505.1 - 0.00029 20.3 0.0 0.00061 19.3 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease zf-piccolo PF05715.8 EPE27506.1 - 0.047 13.6 5.8 0.94 9.5 0.3 2.4 2 0 0 2 2 2 0 Piccolo Zn-finger HATPase_c PF02518.21 EPE27507.1 - 2.7e-21 75.3 0.1 8.2e-21 73.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE27507.1 - 6e-21 74.5 0.1 1.2e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EPE27507.1 - 5.6e-11 42.2 0.0 1.3e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EPE27507.1 - 2.2e-07 31.1 0.0 8.2e-05 22.9 0.0 2.7 2 0 0 2 2 2 1 PAS domain GAF_3 PF13492.1 EPE27507.1 - 5.1e-05 23.3 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 GAF domain PAS_4 PF08448.5 EPE27507.1 - 0.00027 20.9 0.0 0.0012 18.9 0.0 2.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EPE27507.1 - 0.0027 17.4 0.0 0.048 13.5 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EPE27507.1 - 0.0036 17.0 0.0 0.016 14.9 0.0 2.2 2 1 0 2 2 2 1 PAS fold FAD_binding_3 PF01494.14 EPE27508.1 - 5.1e-17 61.9 0.0 8.4e-17 61.2 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EPE27508.1 - 1.9e-06 28.1 0.0 0.00013 22.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE27508.1 - 2.3e-05 24.3 0.2 0.00012 21.9 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE27508.1 - 2.3e-05 23.4 0.0 0.00026 20.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE27508.1 - 2.8e-05 24.0 0.1 8.1e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EPE27508.1 - 0.00013 20.5 0.0 0.00021 19.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.5 EPE27508.1 - 0.00013 20.8 0.0 0.00028 19.8 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase GIDA PF01134.17 EPE27508.1 - 0.0022 16.9 0.1 0.0036 16.2 0.0 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EPE27508.1 - 0.0022 17.1 0.2 0.045 12.8 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EPE27508.1 - 0.0026 17.3 0.0 0.0069 15.9 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EPE27508.1 - 0.035 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EPE27508.1 - 0.045 12.6 0.0 0.081 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EPE27508.1 - 0.076 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Peptidase_M24 PF00557.19 EPE27509.1 - 1.5e-38 132.4 0.1 1.9e-38 132.1 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EPE27509.1 - 0.00086 19.1 4.8 0.00086 19.1 3.3 2.2 2 0 0 2 2 2 1 MYND finger Cornichon PF03311.9 EPE27510.1 - 3.2e-47 159.8 13.6 8.2e-40 135.9 4.0 2.2 2 0 0 2 2 2 2 Cornichon protein WD40 PF00400.27 EPE27511.1 - 1.3e-40 135.8 9.4 5.1e-10 38.8 0.1 7.1 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EPE27511.1 - 7.2e-05 21.1 0.3 0.025 12.7 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EPE27511.1 - 0.00054 19.7 1.8 0.18 11.5 0.1 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.11 EPE27512.1 - 1.8e-09 36.7 12.7 2.5e-09 36.3 8.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE27512.1 - 0.0041 15.7 5.3 0.0046 15.5 3.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Got1 PF04178.7 EPE27512.1 - 0.098 12.7 5.9 0.085 12.9 0.8 2.1 2 0 0 2 2 2 0 Got1/Sft2-like family Myc_N PF01056.13 EPE27514.1 - 0.04 13.0 0.1 0.065 12.3 0.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Anillin PF08174.6 EPE27514.1 - 0.094 12.7 0.7 0.52 10.3 0.2 2.3 2 1 0 2 2 2 0 Cell division protein anillin Glyco_hydro_7 PF00840.15 EPE27520.1 - 1.7e-135 451.7 6.7 1.9e-135 451.5 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Vps16_N PF04841.8 EPE27520.1 - 0.21 10.0 0.0 0.6 8.5 0.0 1.6 2 0 0 2 2 2 0 Vps16, N-terminal region GrpE PF01025.14 EPE27521.1 - 0.19 11.2 8.4 0.35 10.3 5.8 1.4 1 0 0 1 1 1 0 GrpE ScpA_ScpB PF02616.9 EPE27521.1 - 0.59 9.6 3.9 0.73 9.3 2.7 1.1 1 0 0 1 1 1 0 ScpA/B protein OmpH PF03938.9 EPE27521.1 - 3 7.7 11.7 4 7.3 8.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Daxx PF03344.10 EPE27522.1 - 0.57 8.6 7.5 0.65 8.4 5.2 1.0 1 0 0 1 1 1 0 Daxx Family Pescadillo_N PF06732.6 EPE27525.1 - 1.1e-110 369.3 4.8 1.2e-110 369.2 0.0 2.4 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EPE27525.1 - 2.2e-10 40.5 0.0 2.6e-09 37.0 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 EPE27526.1 - 1.9e-124 415.4 30.1 2.2e-124 415.2 20.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U RRN9 PF10680.4 EPE27527.1 - 1.1e-19 69.8 0.2 4.3e-19 68.0 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.21 EPE27527.1 - 0.0019 18.4 1.0 0.0019 18.4 0.7 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE27527.1 - 0.014 15.7 0.9 0.014 15.7 0.6 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger RRN3 PF05327.6 EPE27527.1 - 0.75 7.8 4.3 1.1 7.3 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_6 PF12697.2 EPE27529.1 - 1.5e-12 47.9 0.4 2.1e-12 47.4 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE27529.1 - 8.8e-12 44.9 0.2 1.4e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE27529.1 - 1.2e-06 28.3 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EPE27529.1 - 1.6e-05 24.5 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE27529.1 - 7.5e-05 22.0 0.0 0.00017 20.8 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Cutinase PF01083.17 EPE27529.1 - 0.0098 15.6 0.1 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Cutinase Hydrolase_4 PF12146.3 EPE27529.1 - 0.035 13.9 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 EPE27529.1 - 0.059 12.7 0.1 0.13 11.6 0.1 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF818 PF05677.7 EPE27529.1 - 0.075 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) NMT_C PF02799.10 EPE27530.1 - 1e-78 263.1 0.1 2e-78 262.1 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EPE27530.1 - 7.8e-73 243.4 0.1 1.7e-72 242.3 0.0 1.6 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EPE27530.1 - 7.2e-05 22.6 0.1 0.00083 19.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPE27530.1 - 0.031 14.4 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF427 PF04248.7 EPE27530.1 - 0.041 13.5 0.1 0.096 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) SAPS PF04499.10 EPE27530.1 - 1.1 7.8 8.1 1.1 7.7 4.6 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Dicty_REP PF05086.7 EPE27530.1 - 1.2 6.8 5.7 1.7 6.2 4.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Abhydrolase_6 PF12697.2 EPE27531.1 - 4.1e-19 69.3 0.0 8.1e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE27531.1 - 5.1e-16 58.9 0.0 3.6e-15 56.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE27531.1 - 9.3e-08 31.9 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 EPE27531.1 - 0.0016 17.3 0.0 0.0037 16.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Thioesterase PF00975.15 EPE27531.1 - 0.019 15.2 0.3 0.053 13.7 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain Esterase PF00756.15 EPE27531.1 - 0.022 14.2 0.0 0.043 13.2 0.0 1.5 1 1 0 1 1 1 0 Putative esterase PGAP1 PF07819.8 EPE27531.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Dynamin_N PF00350.18 EPE27532.1 - 1.3e-26 93.3 0.1 1.3e-26 93.3 0.1 2.7 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.15 EPE27532.1 - 9.2e-16 57.4 0.1 2.3e-15 56.1 0.1 1.7 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EPE27532.1 - 7.3e-06 25.9 1.2 4e-05 23.5 0.2 2.7 2 1 0 2 2 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPE27532.1 - 0.00015 22.2 0.0 0.00059 20.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein PPP4R2 PF09184.6 EPE27532.1 - 0.004 16.7 10.7 0.0091 15.5 7.4 1.5 1 0 0 1 1 1 1 PPP4R2 AAA_21 PF13304.1 EPE27532.1 - 0.008 16.1 0.0 0.008 16.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPE27532.1 - 0.053 13.8 0.0 0.32 11.2 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Sigma70_ner PF04546.8 EPE27532.1 - 0.065 12.8 9.7 0.21 11.1 6.8 1.9 1 0 0 1 1 1 0 Sigma-70, non-essential region AAA_29 PF13555.1 EPE27532.1 - 0.091 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nop14 PF04147.7 EPE27532.1 - 0.15 9.9 13.0 0.24 9.2 9.0 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 EPE27532.1 - 0.27 10.3 12.5 0.68 9.0 8.7 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 EPE27532.1 - 0.55 9.4 5.9 0.88 8.7 4.1 1.3 1 0 0 1 1 1 0 NOA36 protein PAP_central PF04928.12 EPE27534.1 - 0.088 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain ABM PF03992.11 EPE27535.1 - 1.9e-05 24.6 0.0 0.00088 19.2 0.0 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase CABIT PF12736.2 EPE27537.1 - 0.032 13.2 0.8 0.066 12.2 0.6 1.4 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, TEBP_beta PF07404.6 EPE27537.1 - 0.64 9.0 8.9 1.7 7.7 6.2 1.7 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Med3 PF11593.3 EPE27537.1 - 4.6 6.3 10.1 0.41 9.8 1.9 2.6 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal DUF92 PF01940.11 EPE27538.1 - 3.9e-64 215.8 1.6 5.1e-64 215.5 1.1 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Amidase PF01425.16 EPE27539.1 - 1.8e-68 231.3 0.1 8.9e-63 212.6 0.0 2.1 2 0 0 2 2 2 2 Amidase p450 PF00067.17 EPE27540.1 - 6.9e-66 222.6 0.0 1.1e-56 192.2 0.0 2.6 3 0 0 3 3 3 2 Cytochrome P450 FAD_binding_1 PF00667.15 EPE27540.1 - 2.6e-22 79.3 0.1 4.2e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EPE27540.1 - 5.6e-18 65.3 0.0 1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EPE27540.1 - 7.7e-15 55.4 0.0 1.7e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EPE27540.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Tyrosinase PF00264.15 EPE27541.1 - 8.8e-50 169.9 4.0 1.4e-49 169.2 2.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_114 PF03537.8 EPE27542.1 - 8.5e-23 79.9 0.1 1.6e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 FMN_dh PF01070.13 EPE27542.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DAO PF01266.19 EPE27543.1 - 1e-55 189.0 0.0 1.2e-55 188.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE27543.1 - 4.3e-05 23.4 0.0 0.00011 22.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPE27543.1 - 0.00015 21.9 0.0 0.016 15.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPE27543.1 - 0.0024 16.9 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EPE27543.1 - 0.0028 16.5 0.0 0.0065 15.3 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EPE27543.1 - 0.019 13.4 0.1 0.75 8.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 EPE27543.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4404 PF14357.1 EPE27543.1 - 0.15 12.5 0.2 0.32 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Lycopene_cycl PF05834.7 EPE27543.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EPE27543.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Ifi-6-16 PF06140.8 EPE27545.1 - 0.0028 17.4 29.5 0.0051 16.5 20.1 1.8 1 1 0 1 1 1 1 Interferon-induced 6-16 family CENP-T PF15511.1 EPE27546.1 - 6.5 5.8 11.6 8.8 5.4 8.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Myc_target_1 PF15179.1 EPE27547.1 - 0.038 13.5 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Myc target protein 1 Herpes_gE PF02480.11 EPE27547.1 - 0.048 11.9 0.2 0.05 11.8 0.2 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM52 PF14979.1 EPE27547.1 - 0.21 11.4 1.8 0.34 10.8 1.2 1.4 1 1 0 1 1 1 0 Transmembrane 52 Ifi-6-16 PF06140.8 EPE27550.1 - 4.3e-06 26.4 22.9 7.2e-06 25.7 15.9 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.8 EPE27551.1 - 0.9 9.3 20.9 1.9 8.2 14.5 1.6 1 1 0 1 1 1 0 Interferon-induced 6-16 family Beta_helix PF13229.1 EPE27552.1 - 0.12 12.1 3.2 0.22 11.2 2.2 1.5 1 1 0 1 1 1 0 Right handed beta helix region Ctr PF04145.10 EPE27553.1 - 3.7 7.6 4.0 0.99 9.4 0.2 2.0 2 0 0 2 2 2 0 Ctr copper transporter family APH PF01636.18 EPE27555.1 - 2.2e-11 43.9 0.3 1.5e-10 41.2 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EPE27555.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Choline_kinase PF01633.15 EPE27555.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Methyltransf_11 PF08241.7 EPE27556.1 - 2.6e-20 72.7 0.0 4e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE27556.1 - 4.8e-17 61.9 0.0 6.7e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE27556.1 - 1.3e-12 47.7 0.0 2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE27556.1 - 2.6e-09 37.4 0.0 7.3e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE27556.1 - 1.3e-08 35.3 0.0 2.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE27556.1 - 1.9e-08 34.6 0.0 3.1e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPE27556.1 - 7.1e-08 31.8 0.0 9e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EPE27556.1 - 2e-07 30.3 0.0 3.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Sterol_MT_C PF08498.5 EPE27556.1 - 4.8e-06 26.4 0.0 8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_26 PF13659.1 EPE27556.1 - 2.2e-05 24.4 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EPE27556.1 - 0.0042 16.7 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 EPE27556.1 - 0.077 12.3 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain CHAT PF12770.2 EPE27557.1 - 8.2e-27 94.0 0.0 1.9e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 CHAT domain DinB PF05163.7 EPE27557.1 - 0.00024 20.8 0.0 0.00065 19.4 0.0 1.7 1 0 0 1 1 1 1 DinB family Peptidase_C50 PF03568.12 EPE27557.1 - 0.0087 14.7 0.0 0.018 13.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 SIS PF01380.17 EPE27559.1 - 2.8e-12 46.3 0.0 9.1e-12 44.7 0.0 1.9 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EPE27559.1 - 0.00012 21.8 0.0 0.028 14.1 0.0 2.4 1 1 1 2 2 2 2 SIS domain IMS_HHH PF11798.3 EPE27559.1 - 0.022 14.7 0.0 11 6.3 0.1 3.2 2 0 0 2 2 2 0 IMS family HHH motif Pkinase PF00069.20 EPE27561.1 - 1.6e-25 89.7 0.0 2.4e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE27561.1 - 5e-14 51.9 0.0 9e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EPE27562.1 - 1.2e-19 70.5 0.0 2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE27562.1 - 3.4e-12 45.9 0.0 5.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.6 EPE27563.1 - 4.8e-17 62.4 0.2 9.9e-17 61.4 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cyt-b5 PF00173.23 EPE27564.1 - 4.2e-19 68.1 0.3 4.6e-19 67.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 EPE27564.1 - 0.035 14.0 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H BRX PF08381.6 EPE27564.1 - 0.13 11.2 0.6 0.52 9.4 0.4 2.1 1 1 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 DUF2842 PF11003.3 EPE27565.1 - 0.074 12.9 0.8 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2842) TMF_TATA_bd PF12325.3 EPE27568.1 - 0.021 14.5 0.4 0.034 13.8 0.3 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding zf-C2H2_4 PF13894.1 EPE27569.1 - 6.5e-10 38.6 9.5 0.0045 17.2 0.2 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPE27569.1 - 0.077 13.1 5.7 1.5 9.0 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EPE27569.1 - 0.077 13.3 20.5 0.71 10.3 0.1 4.6 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2 PF00096.21 EPE27570.1 - 1e-06 28.7 42.6 0.0036 17.5 0.1 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE27570.1 - 2.9e-05 24.0 49.1 0.0097 16.1 0.1 7.6 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPE27570.1 - 0.005 16.9 22.5 0.4 10.8 0.6 5.7 5 1 0 5 5 5 3 Zinc-finger double-stranded RNA-binding Cyt-b5 PF00173.23 EPE27571.1 - 1.3e-11 44.1 0.0 1.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_12 PF13424.1 EPE27572.1 - 1e-07 31.7 8.5 0.0082 16.0 0.0 5.1 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPE27572.1 - 0.0034 16.9 5.0 0.69 9.6 0.0 3.8 3 1 0 4 4 4 1 TPR repeat TPR_2 PF07719.12 EPE27572.1 - 0.013 15.3 14.0 0.34 10.9 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Enkurin PF13864.1 EPE27572.1 - 0.016 15.3 0.2 0.044 13.9 0.2 1.7 1 0 0 1 1 1 0 Calmodulin-binding TPR_14 PF13428.1 EPE27572.1 - 0.026 15.1 3.1 33 5.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPE27572.1 - 0.029 14.1 1.0 23 5.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPE27572.1 - 0.087 12.4 3.8 25 4.6 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2482 PF10655.4 EPE27572.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) TPR_16 PF13432.1 EPE27572.1 - 0.34 11.6 4.0 10 6.9 0.0 3.8 6 0 0 6 6 6 0 Tetratricopeptide repeat F-protein PF00469.15 EPE27574.1 - 0.088 12.1 0.3 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef DUF2486 PF10667.4 EPE27575.1 - 0.019 15.5 6.1 0.053 14.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) LysM PF01476.15 EPE27577.1 - 3.5e-22 77.9 0.1 3.5e-05 23.5 0.0 6.3 6 0 0 6 6 6 6 LysM domain LysM PF01476.15 EPE27579.1 - 6.8e-10 38.6 0.2 6.4e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 LysM domain Glyco_hydro_18 PF00704.23 EPE27580.1 - 4.1e-70 236.9 0.1 7.7e-70 236.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DNase_NucA_NucB PF14040.1 EPE27580.1 - 3.7e-05 23.8 0.1 0.00028 21.0 0.1 2.4 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB Chitin_bind_1 PF00187.14 EPE27580.1 - 5.6e-05 23.0 16.0 5.6e-05 23.0 11.1 3.6 3 0 0 3 3 3 1 Chitin recognition protein Ceramidase PF05875.7 EPE27582.1 - 7.2e-72 241.6 9.3 8.8e-72 241.3 6.5 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.6 EPE27582.1 - 0.081 12.6 2.1 0.28 10.9 1.5 1.9 1 0 0 1 1 1 0 Trp-operon Leader Peptide ADH_N PF08240.7 EPE27583.1 - 7e-20 70.8 0.5 1.2e-19 70.0 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE27583.1 - 8.7e-11 41.4 0.3 1.5e-10 40.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE27583.1 - 5.6e-07 30.5 0.1 6.2e-06 27.1 0.0 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.20 EPE27583.1 - 0.13 12.1 0.4 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF3970 PF13113.1 EPE27584.1 - 0.013 15.1 0.9 0.019 14.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) Peptidase_M48 PF01435.13 EPE27585.1 - 2.4e-38 131.9 0.0 3.1e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M13 PF01431.16 EPE27585.1 - 0.14 11.3 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M13 Kelch_3 PF13415.1 EPE27586.1 - 4.7e-24 83.9 20.1 1.6e-07 31.2 0.1 7.6 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EPE27586.1 - 2.3e-18 65.7 0.8 0.00022 21.0 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EPE27586.1 - 3e-18 65.1 4.2 6.3e-08 32.4 0.0 5.1 4 2 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 EPE27586.1 - 5.8e-17 61.2 14.7 0.00011 21.9 0.4 7.0 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EPE27586.1 - 9.5e-16 57.0 3.3 8.2e-08 31.6 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EPE27586.1 - 2.7e-13 49.0 6.6 2e-06 27.2 0.0 5.7 5 1 1 6 6 6 3 Kelch motif RAG2 PF03089.9 EPE27586.1 - 0.076 11.7 0.0 0.16 10.6 0.0 1.5 1 0 0 1 1 1 0 Recombination activating protein 2 dCMP_cyt_deam_1 PF00383.17 EPE27587.1 - 7.7e-10 38.3 0.3 1e-09 37.9 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EPE27587.1 - 0.0034 17.0 0.5 0.0046 16.6 0.3 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 EPE27587.1 - 0.1 12.4 0.2 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase Transferase PF02458.10 EPE27588.1 - 1e-36 126.3 0.0 5.4e-34 117.3 0.0 2.4 1 1 0 1 1 1 1 Transferase family ApbA PF02558.11 EPE27589.1 - 3.4e-29 101.2 0.0 6.3e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPE27589.1 - 3.3e-24 85.2 0.0 5.4e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal 2Fe-2S_thioredx PF01257.14 EPE27590.1 - 1.3e-60 203.2 0.1 1.6e-60 202.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin LRR_6 PF13516.1 EPE27591.1 - 1.6e-11 42.9 1.4 0.032 14.2 0.0 7.6 9 0 0 9 9 9 3 Leucine Rich repeat F-box-like PF12937.2 EPE27591.1 - 2.5e-09 36.7 0.0 8.8e-09 34.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 EPE27591.1 - 7.6e-07 28.3 5.1 0.25 11.5 0.4 7.1 6 2 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.1 EPE27591.1 - 2e-06 27.4 2.0 0.00028 20.5 0.1 4.2 4 0 0 4 4 4 1 Leucine rich repeat F-box PF00646.28 EPE27591.1 - 3.2e-06 26.6 0.0 1.2e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 EPE27591.1 - 0.00016 21.2 5.9 0.027 14.0 0.0 4.9 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EPE27591.1 - 0.0032 17.4 5.1 1.9 9.0 0.2 6.1 6 0 0 6 6 6 1 Leucine rich repeat HET PF06985.6 EPE27592.1 - 3.1e-33 114.8 0.0 5.3e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2305 PF10230.4 EPE27594.1 - 1.2e-59 201.9 0.0 1.3e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EPE27594.1 - 7.5e-08 32.5 0.0 1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE27594.1 - 4.2e-05 23.3 0.0 7.1e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EPE27594.1 - 0.0045 16.3 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.8 EPE27594.1 - 0.0081 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EPE27594.1 - 0.019 15.2 0.0 0.039 14.1 0.0 1.5 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_1 PF00561.15 EPE27594.1 - 0.072 12.6 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EPE27594.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SNF2_N PF00176.18 EPE27595.1 - 2.8e-82 275.8 0.7 2.8e-82 275.8 0.5 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EPE27595.1 - 2e-18 66.0 0.1 5.5e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EPE27595.1 - 6.6e-18 64.3 0.0 5.7e-17 61.3 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 EPE27595.1 - 5.4e-17 61.7 0.7 5.4e-17 61.7 0.5 4.4 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EPE27595.1 - 9.3e-14 50.9 13.4 9.3e-14 50.9 9.3 3.5 4 0 0 4 4 4 1 HSA QLQ PF08880.6 EPE27595.1 - 4.1e-13 48.4 1.0 4.1e-13 48.4 0.7 2.5 3 0 0 3 3 3 1 QLQ Mucin PF01456.12 EPE27595.1 - 1.4 8.6 10.5 3.4 7.4 7.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Form_Nir_trans PF01226.12 EPE27596.1 - 1.9e-73 246.4 18.0 2.1e-73 246.2 12.5 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter SpecificRecomb PF10136.4 EPE27596.1 - 0.0029 15.7 1.5 0.0042 15.1 1.0 1.3 1 0 0 1 1 1 1 Site-specific recombinase Peptidase_M18 PF02127.10 EPE27597.1 - 6.8e-161 535.5 0.0 9.6e-161 535.0 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) PBD PF00786.23 EPE27598.1 - 0.005 17.2 0.4 0.019 15.3 0.3 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain TPR_11 PF13414.1 EPE27601.1 - 1.6e-30 104.5 29.2 9.8e-08 31.5 0.7 11.1 9 3 4 13 13 13 8 TPR repeat TPR_8 PF13181.1 EPE27601.1 - 4.9e-23 79.1 14.3 0.0024 17.5 0.0 11.9 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.12 EPE27601.1 - 7.1e-23 78.6 36.1 0.0026 17.5 0.0 13.1 13 1 0 13 13 13 7 Tetratricopeptide repeat TPR_1 PF00515.23 EPE27601.1 - 1.5e-20 71.8 30.6 0.00014 21.3 0.0 11.7 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_19 PF14559.1 EPE27601.1 - 2.2e-18 66.3 26.7 3.5e-05 24.0 0.0 10.4 8 3 2 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 EPE27601.1 - 8.7e-15 54.4 41.7 7.1e-06 25.8 0.3 10.8 9 2 6 15 15 15 6 Tetratricopeptide repeat TPR_14 PF13428.1 EPE27601.1 - 1.3e-14 53.3 37.5 0.0031 18.0 0.0 12.2 12 3 3 15 15 13 5 Tetratricopeptide repeat TPR_17 PF13431.1 EPE27601.1 - 1.7e-12 46.4 11.5 0.081 13.1 0.1 11.5 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPE27601.1 - 2.9e-11 43.7 46.8 0.044 14.4 0.1 12.0 11 2 1 12 12 11 5 Tetratricopeptide repeat TPR_7 PF13176.1 EPE27601.1 - 1.1e-10 40.4 20.7 0.024 14.3 0.0 10.7 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPE27601.1 - 1e-05 25.2 13.6 0.26 11.2 0.0 7.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPE27601.1 - 0.11 13.0 42.6 0.21 12.1 0.0 12.1 16 0 0 16 16 12 0 Tetratricopeptide repeat DUF2834 PF11196.3 EPE27602.1 - 3.3e-06 27.1 0.4 0.015 15.4 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) Arf PF00025.16 EPE27603.1 - 8.1e-40 135.9 0.0 1.2e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EPE27603.1 - 3e-13 49.2 0.0 2.1e-08 33.2 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EPE27603.1 - 2.8e-09 36.4 0.0 3.4e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EPE27603.1 - 5.5e-08 32.3 0.0 9e-08 31.6 0.0 1.4 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 EPE27603.1 - 2.1e-06 27.0 0.0 3.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EPE27603.1 - 4.9e-06 27.0 0.0 1.2e-05 25.8 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EPE27603.1 - 5e-05 22.8 0.0 0.00063 19.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPE27603.1 - 0.00085 19.2 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pro_CA PF00484.14 EPE27604.1 - 1.4e-12 47.9 0.0 1.9e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase GBP_repeat PF02526.9 EPE27604.1 - 0.11 11.9 0.3 0.33 10.3 0.1 1.9 2 0 0 2 2 2 0 Glycophorin-binding protein GMC_oxred_N PF00732.14 EPE27606.1 - 1.1e-47 162.6 0.2 1.9e-47 161.8 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE27606.1 - 8.1e-28 97.5 0.2 5.3e-27 94.8 0.0 2.3 3 0 0 3 3 2 1 GMC oxidoreductase DAO PF01266.19 EPE27606.1 - 3.3e-07 29.5 6.0 3.1e-06 26.3 4.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE27606.1 - 7.8e-07 28.2 1.1 4.6e-05 22.4 1.3 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 EPE27606.1 - 1.2e-05 25.2 0.1 3.8e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE27606.1 - 2.1e-05 24.4 0.7 0.00016 21.6 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE27606.1 - 0.00026 20.1 0.3 0.001 18.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EPE27606.1 - 0.0025 16.3 0.6 0.0057 15.1 0.4 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EPE27606.1 - 0.0053 15.8 0.4 0.0087 15.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DUF1690 PF07956.6 EPE27606.1 - 0.025 14.5 0.4 0.048 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) UDPG_MGDP_dh_N PF03721.9 EPE27606.1 - 0.049 13.0 0.1 0.3 10.4 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 EPE27606.1 - 0.072 12.1 1.6 0.14 11.2 1.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EPE27606.1 - 0.097 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HTH_Tnp_1 PF01527.15 EPE27606.1 - 0.14 12.0 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Transposase Lycopene_cycl PF05834.7 EPE27606.1 - 0.17 10.7 0.6 0.29 10.0 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EPE27606.1 - 0.26 10.0 3.0 0.71 8.6 0.2 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A zf-C3HC4_3 PF13920.1 EPE27608.1 - 0.0051 16.4 5.0 0.0091 15.6 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE27608.1 - 0.0062 16.3 7.4 0.014 15.2 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE27608.1 - 0.34 10.9 11.7 0.058 13.4 5.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE27608.1 - 0.98 9.2 5.8 2 8.2 4.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPE27608.1 - 1.7 8.5 7.9 18 5.2 5.5 2.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPE27608.1 - 2 8.0 6.7 3.9 7.1 4.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Toprim_N PF08275.6 EPE27609.1 - 0.029 14.3 0.1 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain DUF2235 PF09994.4 EPE27610.1 - 4e-72 242.9 0.0 9.7e-72 241.6 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) TPPK_C PF12555.3 EPE27611.1 - 0.17 11.6 7.8 3.1 7.6 2.0 2.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Filament_head PF04732.9 EPE27616.1 - 0.091 13.4 1.0 0.21 12.2 0.7 1.6 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region Lactamase_B_2 PF12706.2 EPE27617.1 - 1.7e-34 119.0 0.3 2.8e-34 118.3 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EPE27617.1 - 8.1e-20 70.0 0.0 1.6e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EPE27617.1 - 1.1e-06 28.4 0.3 1.6e-05 24.6 0.1 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Pkinase PF00069.20 EPE27618.1 - 5.7e-59 199.3 0.0 9.7e-59 198.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE27618.1 - 5.3e-20 71.5 0.1 1.4e-18 66.9 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Mtc PF03820.12 EPE27619.1 - 8.6e-103 343.1 0.1 5.9e-102 340.4 0.0 1.8 1 1 0 1 1 1 1 Tricarboxylate carrier CHAP PF05257.11 EPE27620.1 - 0.0029 17.2 0.9 0.0058 16.2 0.0 1.9 2 0 0 2 2 2 1 CHAP domain DUF371 PF04027.8 EPE27621.1 - 0.037 13.7 0.2 0.29 10.8 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF371) SASRP1 PF15160.1 EPE27621.1 - 0.4 9.8 2.6 0.48 9.6 1.4 1.4 1 1 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 BTB PF00651.26 EPE27622.1 - 2.5e-07 30.6 0.0 4.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_S4e PF00900.15 EPE27623.1 - 0.068 12.8 0.2 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 Ribosomal family S4e YtxH PF12732.2 EPE27623.1 - 0.13 12.6 6.3 0.54 10.6 4.4 2.0 1 0 0 1 1 1 0 YtxH-like protein TCTP PF00838.12 EPE27625.1 - 5.5e-65 218.3 2.7 6.2e-65 218.2 1.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein FA_hydroxylase PF04116.8 EPE27626.1 - 3.1e-18 66.2 9.4 3.1e-18 66.2 6.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cas1_AcylT PF07779.7 EPE27630.1 - 1.3e-114 383.3 25.1 5.3e-114 381.3 17.4 1.8 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EPE27630.1 - 3.8e-30 105.5 0.0 5.7e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p ELO PF01151.13 EPE27631.1 - 6.9e-83 277.7 7.3 8.7e-83 277.4 5.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_S10 PF00450.17 EPE27632.1 - 2.2e-92 310.4 7.0 5.1e-92 309.1 4.8 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.17 EPE27633.1 - 3e-129 431.8 0.8 4e-129 431.4 0.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EPE27633.1 - 2.6e-12 46.9 0.3 4.5e-12 46.1 0.2 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EPE27633.1 - 0.0083 16.0 0.0 0.043 13.6 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family SBDS_C PF09377.5 EPE27634.1 - 1.8e-48 163.3 0.2 3.2e-48 162.5 0.0 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 EPE27634.1 - 5.6e-28 96.5 0.0 9.6e-28 95.8 0.0 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_S13 PF00416.17 EPE27635.1 - 3.3e-40 136.8 1.6 4e-40 136.5 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EPE27635.1 - 0.0067 15.0 0.0 0.0067 15.0 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 EPE27635.1 - 0.11 12.5 0.5 0.22 11.5 0.3 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 DUF2746 PF10874.3 EPE27635.1 - 0.11 12.7 0.2 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Ribosomal_L22 PF00237.14 EPE27636.1 - 1.8e-34 117.8 0.1 2.5e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4506 PF14958.1 EPE27636.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) SMAP PF15477.1 EPE27637.1 - 0.073 13.3 0.1 0.3 11.3 0.1 2.0 1 0 0 1 1 1 0 Small acidic protein family Amidoligase_2 PF12224.3 EPE27638.1 - 0.006 16.2 0.1 0.04 13.5 0.1 2.1 1 1 0 1 1 1 1 Putative amidoligase enzyme PI3K_1B_p101 PF10486.4 EPE27639.1 - 0.01 13.4 1.1 0.014 13.0 0.7 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CorA PF01544.13 EPE27640.1 - 3.3e-07 29.6 3.8 5.8e-06 25.5 3.1 2.4 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Glyco_hydro_10 PF00331.15 EPE27641.1 - 9.5e-96 320.5 2.4 1.1e-95 320.3 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 EPE27641.1 - 0.029 13.9 0.0 0.086 12.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) Cellulase-like PF12876.2 EPE27641.1 - 0.03 14.7 0.0 0.085 13.3 0.0 1.8 1 0 0 1 1 1 0 Sugar-binding cellulase-like SUFU PF05076.8 EPE27642.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Suppressor of fused protein (SUFU) TMPIT PF07851.8 EPE27642.1 - 0.2 10.7 0.7 0.44 9.5 0.5 1.6 1 0 0 1 1 1 0 TMPIT-like protein SUR7 PF06687.7 EPE27643.1 - 1.8e-31 109.3 13.6 2.1e-31 109.1 9.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EPE27643.1 - 2.4e-05 24.0 7.2 2.4e-05 24.0 5.0 2.3 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF1049 PF06305.6 EPE27643.1 - 0.13 11.7 0.0 0.13 11.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF4064 PF13273.1 EPE27643.1 - 3.6 7.7 13.4 0.34 11.0 1.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) YadA_anchor PF03895.10 EPE27643.1 - 5.5 7.0 6.9 6.4 6.8 1.4 2.4 2 0 0 2 2 2 0 YadA-like C-terminal region Clc-like PF07062.7 EPE27643.1 - 7.2 5.8 14.2 0.97 8.6 4.2 2.4 2 1 0 2 2 2 0 Clc-like EthD PF07110.6 EPE27644.1 - 1e-11 45.5 0.6 1.8e-11 44.8 0.4 1.4 1 0 0 1 1 1 1 EthD domain Ank_2 PF12796.2 EPE27645.1 - 3.5e-36 123.3 0.1 3.3e-11 43.3 0.0 5.7 4 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EPE27645.1 - 1.3e-27 94.1 2.2 0.00014 21.4 0.1 10.4 10 1 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.1 EPE27645.1 - 5.2e-27 93.7 2.4 4.5e-06 27.0 0.0 7.3 3 3 5 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE27645.1 - 9.5e-25 86.0 0.6 1.8e-07 31.1 0.0 6.5 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE27645.1 - 1.7e-20 71.0 1.8 0.0019 18.2 0.0 9.5 11 0 0 11 11 11 5 Ankyrin repeat zinc_ribbon_5 PF13719.1 EPE27646.1 - 0.018 14.6 0.3 0.039 13.5 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EPE27646.1 - 0.02 14.5 0.2 0.046 13.4 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Acetone_carb_G PF08882.6 EPE27646.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 Acetone carboxylase gamma subunit Thg1C PF14413.1 EPE27646.1 - 0.065 12.9 0.0 0.51 10.0 0.0 2.2 2 0 0 2 2 2 0 Thg1 C terminal domain F-box-like PF12937.2 EPE27647.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE27647.1 - 0.00026 20.5 0.0 0.00069 19.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain OpgC_C PF10129.4 EPE27648.1 - 0.013 14.2 0.4 0.015 13.9 0.3 1.2 1 0 0 1 1 1 0 OpgC protein DPM3 PF08285.6 EPE27648.1 - 0.079 12.8 1.4 0.11 12.3 0.3 1.8 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) p450 PF00067.17 EPE27649.1 - 3e-21 75.5 0.0 4.3e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TLD PF07534.11 EPE27652.1 - 1.7e-10 41.0 0.1 4.2e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 TLD TC1 PF15063.1 EPE27652.1 - 0.096 12.2 0.2 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Thyroid cancer protein 1 ABC_membrane PF00664.18 EPE27653.1 - 1.9e-80 270.1 30.4 4.4e-45 154.2 7.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPE27653.1 - 1.2e-59 200.5 0.1 3.4e-29 101.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EPE27653.1 - 1.3e-14 53.9 2.5 1.1e-06 28.0 0.8 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE27653.1 - 7.3e-11 42.5 0.0 0.097 12.6 0.2 4.4 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EPE27653.1 - 1.1e-08 35.2 1.0 0.0056 16.6 0.1 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EPE27653.1 - 3e-08 33.0 3.5 0.0029 17.1 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EPE27653.1 - 7.5e-08 33.2 0.9 0.002 18.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPE27653.1 - 9.7e-08 32.2 3.2 0.013 15.6 0.7 3.9 2 2 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EPE27653.1 - 1e-07 31.7 3.9 0.28 10.6 0.0 4.6 5 0 0 5 5 5 2 AAA-like domain DUF258 PF03193.11 EPE27653.1 - 2.2e-07 30.1 0.2 0.045 12.9 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 EPE27653.1 - 5.2e-07 28.6 0.1 0.028 13.0 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_18 PF13238.1 EPE27653.1 - 4.5e-06 26.9 1.2 0.038 14.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EPE27653.1 - 4.8e-06 26.5 0.0 0.092 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EPE27653.1 - 5.8e-06 25.8 2.4 0.065 12.6 0.0 3.7 4 1 0 4 4 3 2 AAA domain SbcCD_C PF13558.1 EPE27653.1 - 2.1e-05 24.3 0.6 0.62 10.0 0.1 4.1 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit DUF2075 PF09848.4 EPE27653.1 - 0.00017 20.6 0.2 0.00048 19.1 0.1 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 EPE27653.1 - 0.00086 19.6 2.0 0.058 13.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EPE27653.1 - 0.0013 18.3 0.2 0.39 10.3 0.0 3.4 3 0 0 3 3 3 1 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 EPE27653.1 - 0.0017 17.9 0.1 0.46 9.9 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 EPE27653.1 - 0.0099 15.0 0.0 0.58 9.2 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MobB PF03205.9 EPE27653.1 - 0.01 15.5 0.5 6.1 6.5 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Sororin PF09666.5 EPE27653.1 - 0.011 15.9 2.3 0.022 14.9 1.6 1.5 1 0 0 1 1 1 0 Sororin protein AAA_5 PF07728.9 EPE27653.1 - 0.011 15.4 0.0 0.76 9.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EPE27653.1 - 0.02 15.0 1.7 8.4 6.6 0.0 3.4 4 0 0 4 4 3 0 RNA helicase AAA PF00004.24 EPE27653.1 - 0.031 14.4 0.0 28 4.8 0.0 3.6 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.1 EPE27653.1 - 0.035 12.6 0.0 5.2 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_14 PF13173.1 EPE27653.1 - 0.063 13.1 0.0 5.8 6.8 0.0 3.1 2 1 1 3 3 3 0 AAA domain Mg_chelatase PF01078.16 EPE27653.1 - 0.07 12.2 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Guanylate_kin PF00625.16 EPE27653.1 - 0.1 12.0 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase MMR_HSR1 PF01926.18 EPE27653.1 - 0.13 12.2 2.5 8.6 6.3 0.5 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Septin PF00735.13 EPE27653.1 - 0.13 11.2 0.6 0.67 8.9 0.1 2.0 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.12 EPE27653.1 - 0.17 11.3 0.1 17 4.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CbiA PF01656.18 EPE27653.1 - 0.36 10.2 1.7 4.3 6.6 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_15 PF13175.1 EPE27653.1 - 0.37 9.7 0.1 25 3.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Polysacc_synt_4 PF04669.8 EPE27654.1 - 5.5e-27 94.3 0.9 3.3e-26 91.8 0.6 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis WD40 PF00400.27 EPE27656.1 - 1.7e-13 49.8 11.9 0.026 14.4 0.0 9.1 10 0 0 10 10 10 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EPE27656.1 - 0.00045 19.7 0.2 0.0063 16.0 0.1 2.6 1 1 0 1 1 1 1 PQQ-like domain Lactonase PF10282.4 EPE27656.1 - 0.057 12.5 0.0 0.93 8.5 0.0 2.1 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller DUF3312 PF11768.3 EPE27656.1 - 0.17 10.1 0.0 0.28 9.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Alpha-amylase PF00128.19 EPE27657.1 - 1.6e-92 310.3 0.1 2.6e-92 309.5 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EPE27657.1 - 0.0018 17.2 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Glyoxalase_2 PF12681.2 EPE27657.1 - 0.037 14.6 0.0 0.22 12.1 0.0 2.2 2 0 0 2 2 2 0 Glyoxalase-like domain DUF3459 PF11941.3 EPE27657.1 - 0.1 12.7 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Glyco_hydro_32N PF00251.15 EPE27658.1 - 1.2e-43 149.6 0.0 1.6e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EPE27658.1 - 2.4e-15 56.6 0.4 4.5e-15 55.8 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.9 EPE27658.1 - 0.018 14.1 0.1 1 8.4 0.1 2.7 2 1 0 2 2 2 0 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 EPE27659.1 - 2.2e-80 270.4 22.0 2.7e-80 270.1 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE27659.1 - 2.6e-22 79.0 25.6 2.6e-22 79.0 17.7 2.0 2 1 1 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE27659.1 - 2e-05 23.0 0.8 3.2e-05 22.3 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EPE27659.1 - 2.2e-05 23.0 33.7 0.00014 20.4 2.9 3.8 2 1 1 4 4 4 3 MFS/sugar transport protein MFS_3 PF05977.8 EPE27659.1 - 0.007 14.5 9.0 0.022 12.8 0.5 2.6 3 0 0 3 3 3 2 Transmembrane secretion effector WD40 PF00400.27 EPE27660.1 - 3.3e-19 67.9 18.1 9.9e-07 28.4 0.2 5.9 5 1 0 5 5 5 4 WD domain, G-beta repeat PQQ_3 PF13570.1 EPE27660.1 - 2.4e-05 24.4 7.1 0.42 10.9 0.2 5.9 6 1 0 6 6 6 1 PQQ-like domain PQQ_2 PF13360.1 EPE27660.1 - 0.00039 19.9 6.2 0.05 13.0 0.2 3.0 2 1 0 2 2 2 2 PQQ-like domain YajC PF02699.10 EPE27660.1 - 0.00039 20.0 0.2 7.9 6.2 0.0 4.0 2 1 2 4 4 4 2 Preprotein translocase subunit BBS2_Mid PF14783.1 EPE27660.1 - 0.00053 19.7 0.2 1.1 9.0 0.0 2.6 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EPE27660.1 - 0.013 13.6 2.5 1.2 7.2 0.0 3.8 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPE27660.1 - 0.039 12.6 2.6 1.3 7.6 0.2 2.3 1 1 1 2 2 2 0 Nup133 N terminal like eIF2A PF08662.6 EPE27660.1 - 0.07 12.8 0.0 0.47 10.1 0.0 2.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EPE27660.1 - 0.091 10.9 0.0 0.19 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Kelch_1 PF01344.20 EPE27660.1 - 0.49 9.9 3.8 6.1 6.4 0.0 3.8 4 1 1 5 5 5 0 Kelch motif Pyr_redox_2 PF07992.9 EPE27662.1 - 2e-28 99.6 0.0 3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE27662.1 - 5.4e-11 42.7 0.0 1.2e-08 35.2 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE27662.1 - 4.4e-06 26.8 0.0 0.0016 18.5 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE27662.1 - 0.00045 19.2 0.1 0.55 9.0 0.0 3.6 2 2 2 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE27662.1 - 0.0098 15.8 0.0 1.7 8.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trehalase_Ca-bi PF07492.6 EPE27662.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain NAD_binding_9 PF13454.1 EPE27662.1 - 0.16 11.7 0.1 1.6 8.4 0.0 2.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding Ribosomal_S5 PF00333.15 EPE27664.1 - 4.4e-29 100.0 1.6 3.1e-28 97.3 1.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EPE27664.1 - 1.1e-21 75.8 0.0 2.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain CBFNT PF08143.6 EPE27664.1 - 7 7.8 10.2 12 7.0 7.1 1.4 1 0 0 1 1 1 0 CBFNT (NUC161) domain Zn_clus PF00172.13 EPE27665.1 - 2.8e-08 33.5 7.4 5.7e-08 32.5 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Reo_sigmaC PF04582.7 EPE27666.1 - 0.042 13.0 0.9 0.071 12.2 0.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein SPT16 PF08644.6 EPE27666.1 - 0.44 10.3 3.4 0.83 9.4 2.4 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) OmpH PF03938.9 EPE27666.1 - 0.5 10.2 5.8 0.8 9.6 4.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 EPE27666.1 - 2.7 6.9 13.8 3.9 6.4 9.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EPE27666.1 - 3.3 7.2 11.5 5.6 6.5 7.9 1.3 1 0 0 1 1 1 0 IncA protein Shugoshin_N PF07558.6 EPE27668.1 - 0.0004 20.0 6.8 0.0012 18.5 4.7 1.8 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF2360 PF10152.4 EPE27668.1 - 0.1 12.9 6.7 6.8 6.9 4.7 2.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PXA PF02194.10 EPE27668.1 - 0.17 11.4 3.5 0.39 10.2 2.3 1.6 2 0 0 2 2 2 0 PXA domain Sigma70_ECF PF07638.6 EPE27668.1 - 0.37 10.4 5.2 0.74 9.4 3.6 1.4 1 0 0 1 1 1 0 ECF sigma factor Nsp1_C PF05064.8 EPE27668.1 - 2 8.0 13.1 0.12 11.9 1.6 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region UPF0184 PF03670.8 EPE27669.1 - 0.035 14.2 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Fungal_trans PF04082.13 EPE27670.1 - 1.9e-14 53.1 0.8 3.5e-14 52.2 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27670.1 - 4.9e-10 39.1 14.2 7.9e-10 38.4 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FA_hydroxylase PF04116.8 EPE27670.1 - 0.31 11.4 5.4 0.056 13.8 0.9 1.9 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily DSPc PF00782.15 EPE27672.1 - 3.6e-24 84.8 0.0 4.2e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ANTAR PF03861.9 EPE27672.1 - 0.066 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 ANTAR domain CDKN3 PF05706.7 EPE27672.1 - 0.13 11.7 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Tom37_C PF11801.3 EPE27673.1 - 7.1e-34 117.0 0.0 1.2e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EPE27673.1 - 8.3e-25 86.8 0.1 8.2e-23 80.4 0.0 2.9 3 0 0 3 3 3 1 Outer mitochondrial membrane transport complex protein NACHT PF05729.7 EPE27675.1 - 1.5e-07 31.2 0.0 4e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EPE27675.1 - 0.0012 18.9 0.4 0.092 12.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 EPE27675.1 - 0.053 13.7 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase SNF2_N PF00176.18 EPE27676.1 - 7.3e-72 241.6 0.2 1e-71 241.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE27676.1 - 1.1e-09 38.0 0.0 5.3e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPE27676.1 - 1.1e-06 28.2 0.0 2.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase tRNA-synt_1 PF00133.17 EPE27677.1 - 2e-154 514.8 0.0 2.9e-154 514.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPE27677.1 - 2.8e-20 72.6 0.0 5e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EPE27677.1 - 1.8e-18 66.4 0.3 6.3e-09 34.9 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 EPE27677.1 - 0.00053 19.5 3.6 0.0011 18.5 2.5 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS UPF0183 PF03676.9 EPE27678.1 - 4.2e-41 140.8 0.0 1.3e-25 89.8 0.0 4.2 4 0 0 4 4 4 4 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 EPE27679.1 - 1.6e-108 362.3 0.1 3.7e-108 361.1 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EPE27679.1 - 1e-08 35.4 0.5 1e-08 35.4 0.3 4.4 4 2 0 4 4 4 1 Kinesin-associated microtubule-binding CIDE-N PF02017.10 EPE27679.1 - 0.0056 16.4 1.3 0.097 12.4 0.2 2.8 2 0 0 2 2 2 1 CIDE-N domain DUF4530 PF15039.1 EPE27679.1 - 0.0062 16.4 0.6 0.54 10.1 0.0 3.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4530) Baculo_PEP_C PF04513.7 EPE27679.1 - 3.8 7.3 24.8 0.43 10.4 0.6 5.9 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3425 PF11905.3 EPE27680.1 - 2.1e-23 82.6 3.5 2.1e-23 82.6 2.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EPE27680.1 - 0.00044 20.1 19.2 0.0012 18.7 13.3 1.7 1 1 0 1 1 1 1 bZIP transcription factor DUF904 PF06005.7 EPE27680.1 - 0.0013 18.9 6.3 0.0026 17.9 4.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) FlxA PF14282.1 EPE27680.1 - 0.042 13.8 4.9 0.083 12.8 3.4 1.5 1 0 0 1 1 1 0 FlxA-like protein Mito_fiss_reg PF05308.6 EPE27680.1 - 0.1 11.9 3.9 0.28 10.5 2.7 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator bZIP_2 PF07716.10 EPE27680.1 - 0.29 11.0 22.8 0.21 11.4 9.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Mitofilin PF09731.4 EPE27680.1 - 0.77 8.3 10.2 1.1 7.8 7.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein BMFP PF04380.8 EPE27680.1 - 5 7.3 10.2 0.13 12.3 2.0 2.0 2 0 0 2 2 2 0 Membrane fusogenic activity Dynamin_N PF00350.18 EPE27681.1 - 4.5e-28 98.1 0.3 1.3e-27 96.6 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EPE27681.1 - 1.7e-16 59.8 0.1 6.2e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EPE27681.1 - 0.00094 19.1 0.0 0.0095 15.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPE27681.1 - 0.0016 18.9 0.0 0.0045 17.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein DUF946 PF06101.6 EPE27682.1 - 8.4e-11 40.5 0.1 1.6e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DUF1302 PF06980.6 EPE27682.1 - 0.035 12.6 0.3 0.055 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) DUF4054 PF13262.1 EPE27682.1 - 0.056 13.7 0.1 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) zf-MYND PF01753.13 EPE27683.1 - 5.2e-08 32.6 10.9 5.2e-08 32.6 7.6 1.9 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 EPE27683.1 - 0.11 12.3 6.7 0.33 10.8 4.6 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF4106 PF13388.1 EPE27683.1 - 0.18 10.7 1.9 0.27 10.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Ecl1 PF12855.2 EPE27683.1 - 3.2 7.1 8.1 12 5.2 5.6 2.0 1 1 0 1 1 1 0 Life-span regulatory factor DUF953 PF06110.6 EPE27684.1 - 9.5e-21 73.4 0.1 1.1e-20 73.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 EPE27684.1 - 0.00033 20.3 0.0 0.00039 20.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EPE27684.1 - 0.0058 16.7 0.0 0.013 15.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EPE27684.1 - 0.043 13.3 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.5 EPE27684.1 - 0.052 13.1 0.0 0.08 12.4 0.0 1.3 1 1 0 1 1 1 0 Redoxin TauD PF02668.11 EPE27685.1 - 6.1e-54 183.3 0.3 7.5e-54 183.1 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EPE27685.1 - 0.0046 17.4 0.1 0.77 10.3 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily zf-CCHC PF00098.18 EPE27687.1 - 1.6e-38 128.8 51.6 4.9e-09 35.6 1.7 6.3 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.1 EPE27687.1 - 3.9e-06 26.4 34.2 0.012 15.3 0.4 5.0 3 1 2 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.1 EPE27687.1 - 2.5e-05 23.8 35.4 0.29 10.8 0.6 5.8 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 EPE27687.1 - 0.057 13.0 1.9 0.057 13.0 1.3 6.1 4 2 1 5 5 5 0 Zinc knuckle RNA_pol_N PF01194.12 EPE27687.1 - 2 8.4 0.0 2 8.4 0.0 4.5 6 0 0 6 6 6 0 RNA polymerases N / 8 kDa subunit Kinesin PF00225.18 EPE27688.1 - 5.3e-111 370.5 1.0 1e-110 369.6 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 EPE27688.1 - 1.7e-41 141.2 0.0 4.7e-41 139.7 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 EPE27688.1 - 1e-06 28.6 1.8 1e-06 28.6 1.2 2.2 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.24 EPE27688.1 - 2.6e-05 24.3 0.0 9.5e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 PH domain V_ATPase_I PF01496.14 EPE27688.1 - 0.069 11.0 9.1 0.021 12.7 2.7 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4404 PF14357.1 EPE27688.1 - 1.2 9.6 12.2 27 5.2 0.0 4.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Erp_C PF06780.6 EPE27688.1 - 7.1 6.4 16.3 1.2 9.0 5.5 3.2 3 1 0 3 3 3 0 Erp protein C-terminus DUF2196 PF09962.4 EPE27689.1 - 1.7e-21 75.7 1.1 2.7e-21 75.1 0.8 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) MFS_1 PF07690.11 EPE27690.1 - 4.3e-37 127.6 51.7 4.3e-37 127.6 35.8 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE27690.1 - 0.00033 19.3 2.3 0.00033 19.3 1.6 3.6 3 1 1 4 4 4 3 Sugar (and other) transporter ArsA_ATPase PF02374.10 EPE27691.1 - 7.8e-113 376.5 0.0 9e-113 376.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EPE27691.1 - 6.2e-17 61.6 0.2 7.7e-16 58.0 0.2 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EPE27691.1 - 4.9e-09 36.3 0.0 1.2e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EPE27691.1 - 5e-06 25.8 0.0 9.9e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EPE27691.1 - 7.1e-05 22.3 0.0 0.0022 17.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EPE27691.1 - 0.0022 17.4 0.0 0.0044 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE27691.1 - 0.0066 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EPE27691.1 - 0.014 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 EPE27691.1 - 0.027 13.8 0.0 0.059 12.7 0.0 1.5 2 0 0 2 2 2 0 YhjQ protein MipZ PF09140.6 EPE27691.1 - 0.029 13.4 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ NB-ARC PF00931.17 EPE27691.1 - 0.045 12.6 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ParA PF10609.4 EPE27691.1 - 0.064 13.1 0.1 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 ParA/MinD ATPase like Tir_receptor_N PF07490.6 EPE27691.1 - 0.095 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus RNA_helicase PF00910.17 EPE27691.1 - 0.13 12.4 0.0 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EPE27691.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Transthyretin PF00576.16 EPE27692.1 - 1.2e-24 86.3 0.1 6e-15 55.1 0.1 2.1 1 1 1 2 2 2 2 HIUase/Transthyretin family PHZA_PHZB PF03284.8 EPE27692.1 - 0.022 13.8 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B GMC_oxred_N PF00732.14 EPE27694.1 - 1.4e-49 168.8 0.0 2.3e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE27694.1 - 4.6e-38 130.7 0.0 6.9e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPE27694.1 - 8.4e-07 28.2 0.5 0.0019 17.1 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE27694.1 - 1.7e-06 27.2 1.1 0.014 14.2 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EPE27694.1 - 0.0058 15.6 0.1 0.011 14.6 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPE27694.1 - 0.0073 16.2 0.2 0.02 14.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE27694.1 - 0.0083 16.1 1.8 0.023 14.7 1.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPE27694.1 - 0.026 14.5 0.1 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE27694.1 - 0.053 11.9 0.7 0.086 11.2 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein Chlamy_scaf PF09675.5 EPE27694.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) Pyr_redox PF00070.22 EPE27694.1 - 0.49 10.8 2.0 4.7 7.6 1.5 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.17 EPE27695.1 - 1.1e-122 409.7 0.7 1.3e-122 409.4 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPE27695.1 - 2.4e-05 23.2 0.3 3.8e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) MBF1 PF08523.5 EPE27698.1 - 2.2e-27 94.8 0.9 3.8e-27 94.0 0.6 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EPE27698.1 - 6.3e-10 38.7 0.0 9.8e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EPE27698.1 - 0.00024 21.0 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EPE27698.1 - 0.0016 18.6 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MRP-L27 PF09809.4 EPE27698.1 - 0.0024 17.4 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 RTC PF01137.16 EPE27698.1 - 0.031 13.0 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase Peptidase_M1 PF01433.15 EPE27699.1 - 1.1e-136 455.9 1.4 1.9e-136 455.2 1.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EPE27699.1 - 2.9e-92 309.3 0.0 5.2e-92 308.5 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EPE27699.1 - 2.5e-20 72.7 0.1 5.7e-20 71.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Mnd1 PF03962.10 EPE27700.1 - 1.5e-48 164.9 0.0 1.8e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Mnd1 family CENP-F_leu_zip PF10473.4 EPE27700.1 - 0.0039 17.0 0.1 0.0067 16.2 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Arrestin_N PF00339.24 EPE27701.1 - 5.5e-19 68.4 0.0 2.5e-18 66.3 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EPE27701.1 - 1.1e-08 35.2 0.0 0.0018 18.3 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain FA_desaturase PF00487.19 EPE27702.1 - 6.9e-24 84.6 16.1 1e-23 84.1 11.2 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EPE27702.1 - 6.1e-08 32.7 0.0 1.6e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3474) DEAD PF00270.24 EPE27704.1 - 5.4e-41 139.9 0.0 4.6e-40 136.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE27704.1 - 9e-26 89.5 0.1 2.2e-25 88.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3334 PF11813.3 EPE27704.1 - 0.043 13.3 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) PRAI PF00697.17 EPE27704.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase ResIII PF04851.10 EPE27704.1 - 0.079 12.7 0.0 0.23 11.2 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2986 PF11661.3 EPE27704.1 - 0.099 12.9 10.8 0.11 12.8 3.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Glyco_hydro_61 PF03443.9 EPE27705.1 - 6.5e-55 186.3 0.0 7.8e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-C2H2 PF00096.21 EPE27707.1 - 4.2e-12 45.6 16.5 4.1e-06 26.7 1.8 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE27707.1 - 4.8e-09 35.9 14.0 0.00013 22.0 3.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE27707.1 - 9.5e-07 28.8 14.6 4.1e-05 23.6 4.5 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EPE27707.1 - 5.3e-06 26.4 8.9 0.00031 20.7 0.7 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPE27707.1 - 8e-05 22.7 9.6 0.00011 22.3 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EPE27707.1 - 0.001 18.9 10.2 0.0071 16.2 0.8 2.8 2 1 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 EPE27707.1 - 6.6 6.5 8.8 4.2 7.2 2.3 2.4 1 1 1 2 2 2 0 BED zinc finger ATP_bind_4 PF01902.12 EPE27708.1 - 4.4e-27 94.8 0.0 1.6e-26 93.0 0.0 1.8 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 EPE27708.1 - 9.5e-14 51.2 0.0 3.3e-08 33.3 0.0 3.0 3 0 0 3 3 3 2 Endoribonuclease L-PSP QueC PF06508.8 EPE27708.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC AAA_11 PF13086.1 EPE27709.1 - 5e-60 203.0 0.0 1.1e-59 201.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EPE27709.1 - 5.5e-48 163.0 0.0 1.2e-47 161.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE27709.1 - 8.3e-13 47.9 0.1 5.9e-12 45.1 0.0 2.5 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 EPE27709.1 - 6.1e-12 45.5 0.0 4.8e-10 39.3 0.0 2.9 2 1 0 2 2 1 1 AAA domain DUF2075 PF09848.4 EPE27709.1 - 1e-05 24.6 0.4 7.6e-05 21.8 0.3 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EPE27709.1 - 2.1e-05 24.4 0.0 6.7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EPE27709.1 - 0.00018 20.8 0.0 0.00035 19.9 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EPE27709.1 - 0.00034 20.2 0.0 0.025 14.2 0.0 2.6 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EPE27709.1 - 0.00066 19.2 0.1 1.2 8.6 0.0 2.9 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EPE27709.1 - 0.00071 19.6 0.2 0.0015 18.5 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain DEAD PF00270.24 EPE27709.1 - 0.0013 18.2 0.0 0.0067 15.9 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 EPE27709.1 - 0.0013 18.1 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.11 EPE27709.1 - 0.0015 17.7 0.4 0.095 11.9 0.0 3.3 4 0 0 4 4 4 1 PhoH-like protein AAA_22 PF13401.1 EPE27709.1 - 0.0018 18.4 0.2 0.026 14.6 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPE27709.1 - 0.0047 16.3 0.0 0.014 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EPE27709.1 - 0.0062 15.4 0.0 0.025 13.4 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.4 EPE27709.1 - 0.0074 14.9 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain UvrD_C PF13361.1 EPE27709.1 - 0.0075 15.7 0.1 0.077 12.4 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Flavi_DEAD PF07652.9 EPE27709.1 - 0.0086 15.8 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain Zot PF05707.7 EPE27709.1 - 0.0091 15.4 0.0 0.039 13.4 0.0 2.1 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_10 PF12846.2 EPE27709.1 - 0.01 15.3 0.0 0.13 11.7 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain PIF1 PF05970.9 EPE27709.1 - 0.016 14.1 0.0 3.2 6.5 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA PF00004.24 EPE27709.1 - 0.031 14.4 0.0 0.089 12.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE27709.1 - 0.038 14.7 0.3 0.15 12.8 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPE27709.1 - 0.078 12.7 0.1 0.63 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF482 PF04339.7 EPE27709.1 - 0.085 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF482 XkdW PF09636.5 EPE27710.1 - 0.024 14.4 0.1 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 XkdW protein MbeD_MobD PF04899.7 EPE27710.1 - 0.12 12.2 1.9 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 MbeD/MobD like SUN PF03856.8 EPE27711.1 - 2.7e-86 288.9 15.5 3.5e-86 288.5 10.7 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Neisseria_TspB PF05616.8 EPE27711.1 - 0.014 13.7 5.3 0.019 13.3 3.7 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Med3 PF11593.3 EPE27711.1 - 1.4 8.0 6.2 1.6 7.8 4.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF202 PF02656.10 EPE27712.1 - 2.1e-25 88.7 5.4 2.1e-25 88.7 3.7 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF202) JSRP PF15312.1 EPE27712.1 - 0.92 9.5 0.0 0.92 9.5 0.0 2.5 3 0 0 3 3 3 0 Junctional sarcoplasmic reticulum protein DUF2205 PF10224.4 EPE27713.1 - 2.7e-31 106.9 0.1 4.6e-31 106.2 0.1 1.3 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) TACC PF05010.9 EPE27713.1 - 0.0081 15.9 2.1 0.013 15.2 1.4 1.4 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) DUF4011 PF13195.1 EPE27713.1 - 0.028 14.4 2.8 0.038 14.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) AAA_32 PF13654.1 EPE27713.1 - 0.072 11.7 0.8 0.084 11.5 0.6 1.2 1 0 0 1 1 1 0 AAA domain Spectrin PF00435.16 EPE27713.1 - 0.082 13.1 1.9 0.12 12.6 1.3 1.3 1 0 0 1 1 1 0 Spectrin repeat RXT2_N PF08595.6 EPE27713.1 - 1.3 8.8 5.3 11 5.7 3.7 2.0 1 1 0 1 1 1 0 RXT2-like, N-terminal NDUF_B8 PF05821.6 EPE27715.1 - 9.2e-07 28.6 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 EPE27716.1 - 2.1e-73 246.7 0.5 3.4e-73 246.0 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE27716.1 - 3.1e-15 55.7 0.0 1.6e-14 53.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE27716.1 - 2.8e-08 33.8 0.1 1.6e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EPE27716.1 - 0.00013 20.9 0.4 0.11 11.2 0.1 2.5 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 TRAPPC10 PF12584.3 EPE27717.1 - 3.6e-29 101.1 0.0 9.1e-29 99.8 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 MBOAT_2 PF13813.1 EPE27717.1 - 3.7e-15 55.7 0.2 9.7e-15 54.4 0.1 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Foie-gras_1 PF11817.3 EPE27717.1 - 3e-07 30.1 0.4 5.5e-07 29.3 0.3 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Claudin_2 PF13903.1 EPE27718.1 - 0.018 14.7 1.1 0.022 14.4 0.8 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction zf-DHHC PF01529.15 EPE27718.1 - 5.9 6.2 7.5 9.4 5.5 5.2 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase BTB PF00651.26 EPE27719.1 - 0.00096 19.1 0.0 0.0034 17.3 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain Grp1_Fun34_YaaH PF01184.14 EPE27721.1 - 2.6e-86 288.3 18.1 3.1e-86 288.0 12.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Fungal_trans_2 PF11951.3 EPE27722.1 - 0.0028 16.3 2.2 0.0028 16.3 1.5 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain GMC_oxred_N PF00732.14 EPE27723.1 - 1.2e-55 188.7 0.0 1.6e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE27723.1 - 8.9e-35 120.0 0.0 1.7e-34 119.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPE27723.1 - 1.8e-05 23.8 0.4 0.023 13.6 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE27723.1 - 0.00016 20.6 0.2 0.091 11.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EPE27723.1 - 0.0032 17.5 0.0 0.044 13.8 0.0 2.6 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE27723.1 - 0.02 14.9 0.1 0.056 13.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE27723.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPE27723.1 - 0.029 14.2 0.1 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EPE27723.1 - 0.055 13.4 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 EPE27723.1 - 0.061 11.7 0.1 0.75 8.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EPE27723.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Collagen_bind_2 PF12904.2 EPE27723.1 - 0.11 12.2 0.2 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Putative collagen-binding domain of a collagenase TLD PF07534.11 EPE27724.1 - 3.2e-31 108.1 0.0 6.6e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 TLD MUG2_C PF08593.5 EPE27724.1 - 9.6e-14 51.3 0.2 2.3e-13 50.1 0.2 1.7 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal HIG_1_N PF04588.8 EPE27725.1 - 1.2e-22 79.3 0.8 2.4e-22 78.4 0.0 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region MAS20 PF02064.10 EPE27725.1 - 0.16 11.9 2.3 0.51 10.2 0.6 2.0 1 1 1 2 2 2 0 MAS20 protein import receptor TPX2 PF06886.6 EPE27725.1 - 2.4 8.3 14.1 5.7 7.0 9.8 1.6 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) PALP PF00291.20 EPE27726.1 - 1.9e-74 250.6 0.6 2.3e-74 250.4 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EPE27726.1 - 2e-42 142.6 0.0 2e-22 78.5 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.13 EPE27727.1 - 1.3e-18 66.6 8.4 2e-18 66.0 5.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Acetyltransf_1 PF00583.19 EPE27728.1 - 2e-14 53.3 0.0 3.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPE27728.1 - 1.1e-06 28.2 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPE27728.1 - 7.2e-06 26.1 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPE27728.1 - 1.1e-05 25.5 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPE27728.1 - 0.00027 21.1 0.0 0.00044 20.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPE27728.1 - 0.00034 20.5 0.0 0.00099 19.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE27728.1 - 0.0069 16.2 0.0 0.013 15.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPE27728.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PLAC8 PF04749.12 EPE27729.1 - 3e-21 75.9 8.3 3.7e-21 75.6 5.8 1.1 1 0 0 1 1 1 1 PLAC8 family zf-CCHC PF00098.18 EPE27729.1 - 0.088 12.7 1.3 0.17 11.8 0.2 2.1 2 0 0 2 2 2 0 Zinc knuckle Cyclin_N PF00134.18 EPE27731.1 - 9.9e-37 125.3 0.6 2.3e-36 124.1 0.4 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPE27731.1 - 7.2e-11 42.0 0.2 1.6e-10 40.9 0.2 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF3746 PF12562.3 EPE27732.1 - 0.026 14.3 0.3 0.06 13.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) FRG1 PF06229.7 EPE27732.1 - 0.043 13.2 0.3 0.1 12.0 0.1 1.7 1 1 0 1 1 1 0 FRG1-like family DUF605 PF04652.11 EPE27733.1 - 0.52 9.6 12.9 0.58 9.4 9.0 1.2 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 EPE27733.1 - 1.1 7.7 10.5 1.4 7.2 7.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Tropomyosin PF00261.15 EPE27735.1 - 0.074 12.1 1.8 0.41 9.7 0.4 2.5 3 0 0 3 3 3 0 Tropomyosin DUF2630 PF10944.3 EPE27735.1 - 0.12 12.4 1.2 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) Myosin_tail_1 PF01576.14 EPE27735.1 - 0.77 7.4 3.3 0.69 7.5 1.3 1.5 1 1 0 1 1 1 0 Myosin tail F-box PF00646.28 EPE27736.1 - 0.0099 15.5 0.0 0.5 10.0 0.0 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EPE27736.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 F-box-like AKNA PF12443.3 EPE27737.1 - 0.052 13.5 0.4 0.35 10.8 0.1 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor CENP-Q PF13094.1 EPE27737.1 - 0.79 9.7 4.5 1.7 8.6 3.1 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2414 PF10309.4 EPE27738.1 - 1.7e-23 82.0 0.0 2.7e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Myb_DNA-bind_4 PF13837.1 EPE27739.1 - 0.12 12.4 3.2 0.12 12.5 0.6 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ureidogly_hydro PF04115.7 EPE27740.1 - 1.1e-51 174.5 0.0 1.3e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase DUF1858 PF08984.6 EPE27740.1 - 0.047 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) AAA PF00004.24 EPE27741.1 - 4e-97 321.5 0.0 2.1e-47 160.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EPE27741.1 - 3.2e-20 71.8 0.7 9.9e-20 70.2 0.3 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EPE27741.1 - 1.3e-13 51.2 0.0 2.3e-07 30.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EPE27741.1 - 3.4e-13 49.6 0.0 2.5e-06 27.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EPE27741.1 - 5.7e-13 48.4 0.0 2.3e-05 23.5 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPE27741.1 - 6e-12 45.4 0.6 4.1e-06 26.5 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPE27741.1 - 2.5e-11 43.8 0.3 0.0022 18.1 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EPE27741.1 - 2.6e-11 44.3 0.0 0.00058 20.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPE27741.1 - 2.8e-10 40.4 0.0 0.0011 18.9 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 EPE27741.1 - 3.7e-09 35.7 0.0 0.0013 17.5 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EPE27741.1 - 8.1e-08 31.8 0.2 0.012 15.0 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EPE27741.1 - 1.3e-07 31.5 0.0 0.0061 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EPE27741.1 - 1.7e-07 30.7 0.0 4.4e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_25 PF13481.1 EPE27741.1 - 3.4e-07 29.8 5.0 0.059 12.7 0.0 4.6 3 2 1 5 5 4 2 AAA domain Zeta_toxin PF06414.7 EPE27741.1 - 3.4e-07 29.5 0.0 0.0049 15.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 EPE27741.1 - 4.4e-07 29.5 1.9 0.014 15.0 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 EPE27741.1 - 4.5e-07 29.2 0.2 0.031 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EPE27741.1 - 2.4e-06 27.6 0.0 0.034 14.3 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 EPE27741.1 - 2.4e-06 26.8 0.7 0.52 9.3 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 EPE27741.1 - 4e-06 27.1 0.0 0.048 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EPE27741.1 - 1.1e-05 24.4 0.0 0.01 14.8 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) ResIII PF04851.10 EPE27741.1 - 1.2e-05 25.2 0.0 0.0076 16.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EPE27741.1 - 1.5e-05 25.0 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 EPE27741.1 - 2.4e-05 24.0 0.3 0.13 11.8 0.0 3.2 4 0 0 4 4 2 2 AAA domain Sigma54_activ_2 PF14532.1 EPE27741.1 - 2.9e-05 24.1 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EPE27741.1 - 2.9e-05 23.5 0.0 0.29 10.5 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EPE27741.1 - 3.8e-05 23.0 0.2 0.31 10.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.22 EPE27741.1 - 4.6e-05 23.7 0.0 0.27 11.5 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Parvo_NS1 PF01057.12 EPE27741.1 - 6.8e-05 21.8 0.0 0.068 12.0 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EPE27741.1 - 8e-05 22.4 0.0 5.5 6.6 0.0 4.1 2 2 2 4 4 4 0 Archaeal ATPase AAA_3 PF07726.6 EPE27741.1 - 0.00038 20.0 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EPE27741.1 - 0.0005 19.7 0.0 0.81 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EPE27741.1 - 0.00066 19.3 0.0 0.85 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 EPE27741.1 - 0.00068 19.3 0.0 1.9 8.0 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein NACHT PF05729.7 EPE27741.1 - 0.0011 18.6 0.0 1.5 8.4 0.0 3.3 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 EPE27741.1 - 0.0012 17.8 0.0 0.5 9.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.5 EPE27741.1 - 0.0014 18.4 0.1 0.0054 16.6 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain NTPase_1 PF03266.10 EPE27741.1 - 0.0028 17.3 1.1 1 9.0 0.0 4.1 5 0 0 5 5 4 1 NTPase NB-ARC PF00931.17 EPE27741.1 - 0.0033 16.3 0.1 0.57 8.9 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain Viral_helicase1 PF01443.13 EPE27741.1 - 0.0042 16.6 0.0 0.56 9.6 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 EPE27741.1 - 0.013 14.7 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 EPE27741.1 - 0.018 14.0 0.0 1 8.2 0.0 2.7 2 1 0 3 3 3 0 KAP family P-loop domain SKI PF01202.17 EPE27741.1 - 0.042 13.7 0.1 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_10 PF12846.2 EPE27741.1 - 0.049 13.0 0.8 10 5.4 0.0 3.6 3 1 1 4 4 4 0 AAA-like domain Zot PF05707.7 EPE27741.1 - 0.084 12.3 0.1 31 3.9 0.1 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) KTI12 PF08433.5 EPE27741.1 - 0.098 11.8 0.2 18 4.3 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 UFD1 PF03152.9 EPE27741.1 - 0.11 11.6 0.0 6 5.9 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 UPF0079 PF02367.12 EPE27741.1 - 0.13 11.8 0.1 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PTPLA PF04387.9 EPE27742.1 - 7.1e-55 184.8 9.6 1.2e-54 184.1 6.6 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Glyco_hydro_71 PF03659.9 EPE27746.1 - 4.2e-61 206.5 2.4 5.2e-61 206.2 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Adaptin_binding PF10199.4 EPE27748.1 - 1.7e-14 54.2 6.9 1.7e-14 54.2 4.8 2.2 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 LSM PF01423.17 EPE27748.1 - 3.3e-13 48.9 0.4 6.4e-13 48.0 0.2 1.5 1 0 0 1 1 1 1 LSM domain PGP_phosphatase PF09419.5 EPE27749.1 - 1.9e-58 196.5 0.0 2.3e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EPE27749.1 - 7.4e-08 31.9 0.0 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Homeobox PF00046.24 EPE27750.1 - 1e-19 69.8 3.3 2.1e-19 68.8 2.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EPE27750.1 - 0.00023 20.7 0.6 0.00056 19.5 0.4 1.6 1 0 0 1 1 1 1 Homeobox KN domain E1-E2_ATPase PF00122.15 EPE27751.1 - 2e-19 69.5 0.2 5.6e-19 68.0 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPE27751.1 - 2.2e-18 67.4 0.5 2.3e-14 54.3 0.9 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPE27751.1 - 1.4e-15 57.9 0.0 2.1e-14 54.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPE27751.1 - 1.6e-12 47.2 0.0 6.2e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPE27751.1 - 2.1e-05 24.2 0.2 4.6e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EPE27751.1 - 0.089 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Aha1_N PF09229.6 EPE27752.1 - 4.4e-37 126.9 0.4 7.9e-37 126.1 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EPE27752.1 - 2.8e-19 69.4 0.4 5.8e-19 68.4 0.1 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EPE27752.1 - 0.0008 19.5 1.3 0.026 14.7 0.2 2.1 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Pox_A12 PF04651.8 EPE27752.1 - 0.062 13.4 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein Na_Ca_ex PF01699.19 EPE27754.1 - 1.6 8.3 6.1 1.1 8.8 2.7 1.9 2 1 0 2 2 2 0 Sodium/calcium exchanger protein WD40 PF00400.27 EPE27755.1 - 2.4e-56 185.7 12.0 5.7e-10 38.6 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EPE27755.1 - 8.7e-12 44.5 0.0 1.7e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE27755.1 - 1.8e-10 40.1 0.1 7.7e-10 38.1 0.0 2.1 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 EPE27755.1 - 5.1e-08 31.5 5.3 0.21 9.6 0.0 5.7 2 2 3 6 6 6 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EPE27755.1 - 0.00067 19.1 0.4 0.92 8.9 0.0 3.2 2 1 0 3 3 3 2 PQQ-like domain CPSF_A PF03178.10 EPE27755.1 - 0.0046 16.0 0.0 0.013 14.5 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region UMPH-1 PF05822.7 EPE27755.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) PRANC PF09372.5 EPE27755.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 PRANC domain HORMA PF02301.13 EPE27756.1 - 2.7e-11 43.3 0.0 5.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 HORMA domain UPF1_Zn_bind PF09416.5 EPE27756.1 - 0.035 13.6 0.6 0.068 12.7 0.4 1.4 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) PHD PF00628.24 EPE27756.1 - 0.82 9.4 10.8 1.8 8.3 7.5 1.6 1 0 0 1 1 1 0 PHD-finger Nuc_sug_transp PF04142.10 EPE27758.1 - 4.3e-72 242.1 7.0 8.1e-72 241.2 4.9 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EPE27758.1 - 4e-07 29.2 11.7 4.9e-06 25.6 8.0 2.1 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EPE27758.1 - 8e-06 26.0 11.2 0.00016 21.8 0.5 2.5 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 EPE27758.1 - 0.00053 19.6 18.7 0.029 14.0 8.5 2.6 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EPE27758.1 - 0.0015 18.5 18.2 0.068 13.2 0.4 2.7 2 1 0 2 2 2 2 EamA-like transporter family Sec63 PF02889.11 EPE27759.1 - 1.1e-47 162.8 0.0 1.7e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EPE27759.1 - 3.6e-26 91.6 0.0 9.7e-26 90.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE27759.1 - 2.4e-08 33.7 0.0 7.8e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE27759.1 - 1e-06 28.7 0.0 2.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 EPE27759.1 - 0.0005 20.1 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_22 PF13401.1 EPE27759.1 - 0.017 15.2 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 EPE27759.1 - 0.022 14.3 0.0 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 Helicase UvrD-helicase PF00580.16 EPE27759.1 - 0.024 13.9 1.5 0.15 11.3 0.0 2.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 EPE27759.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPE27759.1 - 0.084 11.7 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EPE27759.1 - 0.097 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF2142 PF09913.4 EPE27760.1 - 0.028 13.0 2.4 0.035 12.7 1.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF1129 PF06570.6 EPE27760.1 - 0.63 9.3 3.8 1.6 7.9 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Complex1_51K PF01512.12 EPE27761.1 - 4.9e-47 159.4 0.0 7.5e-47 158.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EPE27761.1 - 3.6e-18 64.4 0.9 3.6e-18 64.4 0.7 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EPE27761.1 - 4e-09 36.2 0.0 8.5e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Hexapep PF00132.19 EPE27762.1 - 2.5e-10 39.3 14.3 2.1e-05 23.8 0.6 4.2 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EPE27762.1 - 0.00073 19.0 19.6 0.095 12.2 6.1 4.1 2 2 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase TPR_MLP1_2 PF07926.7 EPE27763.1 - 1.9e-31 108.5 22.0 1.9e-31 108.5 15.3 17.5 6 4 7 14 14 14 5 TPR/MLP1/MLP2-like protein CALCOCO1 PF07888.6 EPE27763.1 - 0.00015 20.2 34.0 0.00015 20.2 23.5 10.0 3 2 5 9 9 9 1 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.4 EPE27763.1 - 0.00036 20.3 16.9 0.00036 20.3 11.7 17.5 6 5 9 16 16 16 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TFIIE_beta PF02186.10 EPE27764.1 - 3.4e-06 26.9 0.0 1.4e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 TFIIE beta subunit core domain Thymidylat_synt PF00303.14 EPE27764.1 - 0.08 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Thymidylate synthase FXR1P_C PF12235.3 EPE27764.1 - 0.15 12.1 5.2 0.039 14.0 1.4 1.6 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal DSBA PF01323.15 EPE27765.1 - 4.4e-36 124.2 0.0 5e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EPE27765.1 - 4.4e-05 23.5 0.0 0.00066 19.7 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 EPE27765.1 - 4.6e-05 23.5 0.0 0.077 13.2 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EPE27765.1 - 0.0034 17.1 0.1 0.34 10.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain zf-C2H2 PF00096.21 EPE27767.1 - 1.1e-22 78.9 25.8 2.6e-05 24.2 1.2 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPE27767.1 - 1e-21 76.0 30.7 1.9e-07 31.0 0.3 5.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPE27767.1 - 1.3e-16 59.6 23.9 0.00028 21.0 2.6 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPE27767.1 - 5e-06 26.4 5.2 4.3 7.5 0.0 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EPE27767.1 - 0.0013 18.5 13.0 1.4 8.9 0.8 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EPE27767.1 - 0.01 15.9 12.4 5.2 7.4 0.5 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EPE27767.1 - 0.018 14.6 6.1 1.2 8.9 0.4 3.9 4 0 0 4 4 4 0 zinc-finger of a C2HC-type XPA_N PF01286.13 EPE27767.1 - 0.088 12.5 0.3 0.088 12.5 0.2 3.2 4 0 0 4 4 4 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 EPE27767.1 - 0.61 10.0 11.9 19 5.3 0.1 4.0 2 1 2 4 4 4 0 Zinc ribbon domain zf-TRAF PF02176.13 EPE27767.1 - 0.95 9.8 10.1 3.2 8.1 1.0 2.6 1 1 0 2 2 2 0 TRAF-type zinc finger DHBP_synthase PF00926.14 EPE27768.1 - 2.9e-71 238.7 0.0 5.5e-71 237.8 0.0 1.4 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.1 EPE27769.1 - 5.6e-20 71.6 0.0 7.7e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE27769.1 - 4.3e-16 59.1 0.0 6.5e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE27769.1 - 1e-15 57.6 0.0 1.3e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE27769.1 - 4.6e-13 49.7 0.0 6.7e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE27769.1 - 6.6e-13 48.9 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE27769.1 - 5.2e-09 36.1 0.0 1.2e-07 31.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPE27769.1 - 5.8e-08 32.2 0.0 8.1e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EPE27769.1 - 8.3e-08 32.5 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPE27769.1 - 1.8e-05 23.9 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EPE27769.1 - 0.00025 20.4 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Telomere_Sde2_2 PF13297.1 EPE27769.1 - 0.092 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Telomere stability C-terminal Peptidase_S10 PF00450.17 EPE27771.1 - 2.3e-76 257.6 0.1 6.4e-76 256.1 0.1 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Secretin PF00263.16 EPE27773.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein Rad60-SLD PF11976.3 EPE27774.1 - 0.00071 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EPE27774.1 - 0.0022 17.3 0.0 0.0042 16.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EPE27774.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPE27774.1 - 0.073 13.2 0.1 0.15 12.2 0.0 1.5 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain 4HBT PF03061.17 EPE27775.1 - 0.00019 21.4 0.0 0.00023 21.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EPE27775.1 - 2.2 7.1 4.3 2.6 6.9 3.0 1.4 1 1 0 1 1 1 0 Acyl-ACP thioesterase MFS_1 PF07690.11 EPE27776.1 - 6.7e-39 133.5 22.9 6.7e-39 133.5 15.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE27776.1 - 4.4e-11 42.0 22.9 6.1e-11 41.5 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Trp_oprn_chp PF09534.5 EPE27776.1 - 0.056 13.0 4.7 0.14 11.7 3.2 1.6 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Cu-oxidase_3 PF07732.10 EPE27778.1 - 3.3e-40 136.4 4.8 5.2e-40 135.8 0.7 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPE27778.1 - 7.1e-38 129.2 1.1 7.1e-38 129.2 0.8 3.1 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EPE27778.1 - 1.2e-36 126.0 4.4 4.4e-36 124.1 0.5 2.8 3 1 0 3 3 3 1 Multicopper oxidase UPF0546 PF10639.4 EPE27779.1 - 3.7e-37 126.5 1.0 8.9e-37 125.3 0.7 1.5 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EPE27779.1 - 0.0017 18.3 6.3 0.0037 17.2 2.9 2.1 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EPE27779.1 - 2.5 8.3 7.7 0.83 9.8 3.1 1.8 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF2011 PF09428.5 EPE27780.1 - 0.0051 16.7 0.0 0.028 14.3 0.0 2.2 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Dec-1 PF04624.9 EPE27780.1 - 0.13 11.9 0.8 0.3 10.7 0.5 1.6 1 0 0 1 1 1 0 Dec-1 repeat Proteasome PF00227.21 EPE27781.1 - 1.1e-46 158.4 0.0 1.6e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPE27781.1 - 1.5e-12 46.5 0.5 2.7e-12 45.7 0.4 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 EPE27781.1 - 0.075 12.5 0.7 0.17 11.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) DUF2373 PF10180.4 EPE27782.1 - 1.1e-23 82.4 0.1 2.3e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Transferase PF02458.10 EPE27782.1 - 0.033 12.6 5.2 0.061 11.7 3.6 1.4 1 0 0 1 1 1 0 Transferase family Vmethyltransf_C PF08456.5 EPE27782.1 - 0.053 12.9 0.3 0.053 12.9 0.2 1.8 2 0 0 2 2 2 0 Viral methyltransferase C-terminal SpoVR PF04293.8 EPE27782.1 - 0.3 9.4 3.4 0.49 8.7 2.4 1.3 1 0 0 1 1 1 0 SpoVR like protein SLAC1 PF03595.12 EPE27783.1 - 0.0035 16.0 1.9 0.0035 16.0 1.3 1.8 2 0 0 2 2 2 1 Voltage-dependent anion channel L_HGMIC_fpl PF10242.4 EPE27783.1 - 0.0035 17.3 6.2 0.0092 15.9 4.3 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.6 EPE27783.1 - 0.042 13.5 6.7 0.069 12.8 4.6 1.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Pox_A14 PF05767.7 EPE27783.1 - 0.068 13.1 2.9 0.36 10.8 1.1 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Competence PF03772.11 EPE27783.1 - 0.52 9.3 8.1 0.04 12.9 2.1 1.7 2 1 0 2 2 2 0 Competence protein Glyco_hydro_65m PF03632.10 EPE27784.1 - 4.9e-74 249.2 5.1 3.1e-73 246.6 3.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EPE27784.1 - 3.4e-22 78.9 0.1 1.2e-21 77.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.20 EPE27784.1 - 0.00089 19.0 0.4 0.017 14.9 0.0 3.2 2 1 0 2 2 2 1 F5/8 type C domain Dabb PF07876.7 EPE27785.1 - 5.1e-20 71.7 0.3 7.7e-20 71.1 0.2 1.3 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ArfGap PF01412.13 EPE27786.1 - 9.9e-31 105.9 0.1 2.7e-28 98.1 0.0 3.9 5 0 0 5 5 5 2 Putative GTPase activating protein for Arf Cupin_5 PF06172.6 EPE27787.1 - 3.7e-25 88.4 0.0 4.6e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) C2 PF00168.25 EPE27788.1 - 3.5e-13 49.2 0.0 6.6e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain HA2 PF04408.18 EPE27789.1 - 2.2e-28 98.2 0.1 5.3e-28 97.0 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EPE27789.1 - 2.3e-20 72.5 0.0 5.1e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EPE27789.1 - 1.1e-12 47.6 0.0 2.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EPE27789.1 - 7.7e-10 38.7 0.0 1.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EPE27789.1 - 3.8e-06 26.5 0.2 1e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPE27789.1 - 2.8e-05 24.2 0.0 6.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE27789.1 - 0.00045 19.9 0.2 0.0024 17.5 0.2 2.1 2 0 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 EPE27789.1 - 0.00082 18.3 0.0 0.0019 17.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EPE27789.1 - 0.028 14.3 0.4 0.25 11.2 0.3 2.2 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EPE27789.1 - 0.032 14.3 0.2 0.17 11.9 0.0 2.3 3 0 0 3 3 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 EPE27789.1 - 0.045 14.0 2.1 0.94 9.7 0.1 3.3 3 1 1 4 4 3 0 ABC transporter ResIII PF04851.10 EPE27789.1 - 0.059 13.2 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PBP_like_2 PF12849.2 EPE27789.1 - 0.081 12.3 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 PBP superfamily domain PhoH PF02562.11 EPE27789.1 - 0.098 11.8 0.3 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.1 EPE27789.1 - 0.12 12.7 0.1 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Herpes_ori_bp PF02399.10 EPE27789.1 - 0.27 9.1 0.0 0.4 8.5 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein zf-RING_2 PF13639.1 EPE27790.1 - 1e-05 25.2 11.1 2e-05 24.2 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPE27790.1 - 5.3e-05 22.7 8.5 9.2e-05 22.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE27790.1 - 0.00012 21.9 7.9 0.00023 21.1 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE27790.1 - 0.00069 19.2 9.7 0.0012 18.5 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE27790.1 - 0.0063 16.5 9.7 0.02 14.9 6.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-MIZ PF02891.15 EPE27790.1 - 2.4 7.7 9.0 4.3 6.9 6.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_5 PF14634.1 EPE27790.1 - 3.8 7.3 10.6 8.4 6.2 7.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Abhydrolase_6 PF12697.2 EPE27791.1 - 7.2e-16 58.7 0.1 1.1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE27791.1 - 2e-06 27.6 0.0 3.5e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE27791.1 - 0.022 13.9 0.1 1.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EPE27791.1 - 0.083 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Methyltransf_23 PF13489.1 EPE27792.1 - 1.9e-17 63.4 0.0 3.1e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE27792.1 - 4.1e-08 33.6 0.0 2.4e-07 31.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE27792.1 - 3.8e-07 30.5 0.0 9.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE27792.1 - 2.3e-06 27.2 0.0 1.6e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE27792.1 - 4.2e-05 24.0 0.0 0.00032 21.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE27792.1 - 0.0024 18.1 0.0 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.7 EPE27792.1 - 0.022 14.2 0.0 0.054 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) FtsJ PF01728.14 EPE27792.1 - 0.034 14.1 0.0 0.088 12.7 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EPE27792.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Pyridoxal_deC PF00282.14 EPE27793.1 - 6.6e-31 107.0 0.0 8.9e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EPE27793.1 - 0.00044 19.4 0.0 0.00074 18.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EPE27793.1 - 0.00049 19.1 0.0 0.00074 18.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2462 PF09495.5 EPE27794.1 - 4e-19 69.1 7.8 4e-19 69.1 5.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) Arginase PF00491.16 EPE27796.1 - 1.1e-88 297.2 0.0 1.4e-88 296.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EPE27796.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain Shisa PF13908.1 EPE27797.1 - 4.4e-06 26.9 0.0 6.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF2668 PF10873.3 EPE27797.1 - 0.027 14.6 0.7 0.05 13.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Amino_oxidase PF01593.19 EPE27798.1 - 4.6e-50 171.0 0.1 1.7e-41 142.7 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPE27798.1 - 1.5e-06 28.1 0.0 3.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPE27798.1 - 0.00014 21.9 0.5 0.00046 20.3 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EPE27798.1 - 0.0045 17.0 0.1 0.008 16.2 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EPE27798.1 - 0.0093 15.0 0.1 0.089 11.8 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain ThiF PF00899.16 EPE27798.1 - 0.0098 15.7 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 ThiF family Pyr_redox_2 PF07992.9 EPE27798.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE27798.1 - 0.16 10.8 0.3 0.7 8.7 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPE27798.1 - 0.17 12.3 0.2 1.1 9.7 0.1 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Adaptin_N PF01602.15 EPE27799.1 - 0.16 10.2 0.5 0.21 9.8 0.3 1.3 1 0 0 1 1 1 0 Adaptin N terminal region SseC PF04888.7 EPE27799.1 - 1.5 8.0 11.0 3.4 6.9 7.6 1.6 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Cytochrom_B561 PF03188.11 EPE27800.1 - 2.2e-10 40.5 11.1 3.8e-10 39.7 7.7 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EPE27800.1 - 5.5e-09 35.5 2.3 1.6e-08 34.0 1.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF4079 PF13301.1 EPE27800.1 - 0.24 11.4 9.3 1.5 8.7 5.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF2306 PF10067.4 EPE27800.1 - 2.9 8.0 15.7 0.13 12.3 0.8 3.4 3 1 1 4 4 4 0 Predicted membrane protein (DUF2306) RseC_MucC PF04246.7 EPE27800.1 - 5.5 6.5 14.2 0.16 11.5 0.5 3.5 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC GFO_IDH_MocA PF01408.17 EPE27801.1 - 1.8e-16 60.7 0.0 5e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPE27801.1 - 3.8e-07 29.8 0.0 6.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PI-PLC-X PF00388.14 EPE27802.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain SPOB_a PF14689.1 EPE27802.1 - 0.034 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain Sigma54_AID PF00309.15 EPE27802.1 - 0.063 12.7 1.3 0.064 12.7 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) Zn_clus PF00172.13 EPE27803.1 - 9.4e-10 38.2 10.7 1.7e-09 37.4 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1515 PF07439.6 EPE27803.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) UAF_Rrn10 PF05234.6 EPE27805.1 - 0.0017 18.3 0.1 0.0035 17.3 0.0 1.5 1 1 0 1 1 1 1 UAF complex subunit Rrn10 Adhesin_P1 PF03257.8 EPE27805.1 - 0.074 13.3 4.3 0.088 13.1 0.3 2.6 2 0 0 2 2 2 0 Mycoplasma adhesin P1 Cyclase PF04199.8 EPE27806.1 - 1.8e-09 37.4 0.0 3.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase MFS_1 PF07690.11 EPE27807.1 - 7.8e-37 126.7 32.7 7.8e-37 126.7 22.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EPE27807.1 - 0.039 12.0 8.6 0.014 13.4 0.6 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3493 PF11998.3 EPE27807.1 - 0.14 12.0 0.6 22 5.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) WD40 PF00400.27 EPE27808.1 - 3e-18 64.9 4.8 5.4e-09 35.5 0.2 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_2 PF13360.1 EPE27808.1 - 0.0095 15.4 0.4 4.2 6.7 0.1 3.0 3 0 0 3 3 3 2 PQQ-like domain Clr5 PF14420.1 EPE27809.1 - 3.7e-06 26.7 0.0 7.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Clr5 domain HD PF01966.17 EPE27809.1 - 4.7e-05 23.3 0.1 0.00018 21.5 0.1 2.0 1 1 0 1 1 1 1 HD domain Arg_repressor PF01316.16 EPE27809.1 - 0.14 11.7 0.0 9.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain F-box PF00646.28 EPE27810.1 - 2.9e-06 26.8 0.1 5.8e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE27810.1 - 3e-06 26.8 0.2 7.3e-06 25.6 0.1 1.7 1 1 0 1 1 1 1 F-box-like CFEM PF05730.6 EPE27812.1 - 4.9e-11 42.2 9.9 9.5e-11 41.3 6.8 1.5 1 0 0 1 1 1 1 CFEM domain 4HBT_2 PF13279.1 EPE27813.1 - 7.9e-07 29.5 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF2530 PF10745.4 EPE27814.1 - 0.012 15.6 1.6 0.028 14.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF4131 PF13567.1 EPE27814.1 - 6.3 6.1 14.1 6.4 6.1 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Ammonium_transp PF00909.16 EPE27815.1 - 8.7e-96 320.8 23.0 4.4e-95 318.4 15.9 1.8 1 1 0 1 1 1 1 Ammonium Transporter Family Cellulase PF00150.13 EPE27817.1 - 2.6e-19 69.5 3.9 3.2e-19 69.2 2.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EPE27817.1 - 0.00072 18.5 0.0 0.0032 16.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4434 PF14488.1 EPE27817.1 - 0.0082 15.8 0.2 0.017 14.8 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4434) Glyco_hydro_42 PF02449.10 EPE27817.1 - 0.0085 15.2 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 Beta-galactosidase Cellulase-like PF12876.2 EPE27817.1 - 0.0091 16.4 0.0 0.031 14.7 0.0 2.0 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_10 PF00331.15 EPE27817.1 - 0.012 14.6 0.4 0.027 13.5 0.1 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 10 Pkinase PF00069.20 EPE27819.1 - 4.7e-44 150.4 0.0 3e-42 144.5 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE27819.1 - 1.5e-25 89.8 0.0 1.5e-24 86.5 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE27819.1 - 0.22 10.4 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 EPE27819.1 - 1.1 7.9 0.0 1.6 7.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Vac7 PF12751.2 EPE27820.1 - 5.1e-142 473.2 15.1 1e-127 426.2 2.2 2.6 2 0 0 2 2 2 2 Vacuolar segregation subunit 7 PXA PF02194.10 EPE27821.1 - 6.3e-39 133.4 1.9 1.7e-38 132.0 0.0 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EPE27821.1 - 7.7e-21 74.2 0.1 7.7e-21 74.2 0.0 2.0 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EPE27821.1 - 8.4e-10 38.4 0.0 1.1e-07 31.6 0.0 2.8 2 0 0 2 2 2 1 PX domain Serglycin PF04360.7 EPE27821.1 - 0.046 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Serglycin PC4 PF02229.11 EPE27822.1 - 4.5e-19 67.4 0.4 1.1e-18 66.2 0.0 1.8 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) Hydantoinase_B PF02538.9 EPE27823.1 - 8.5e-201 667.7 0.1 7.5e-200 664.6 0.0 2.0 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EPE27823.1 - 1.7e-92 309.6 0.7 2.9e-92 308.8 0.5 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EPE27823.1 - 5.2e-57 192.1 0.9 2e-55 187.0 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Ank_2 PF12796.2 EPE27824.1 - 0.0047 17.2 0.0 0.024 14.9 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF2296 PF10058.4 EPE27824.1 - 0.36 10.5 2.9 0.72 9.6 2.0 1.4 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) zf-RING_4 PF14570.1 EPE27824.1 - 1.5 8.4 5.0 0.38 10.3 1.0 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EPE27824.1 - 2.3 8.1 8.2 0.23 11.3 2.4 1.8 2 0 0 2 2 2 0 Ring finger domain 4HBT PF03061.17 EPE27825.1 - 7.5e-13 48.4 0.1 1.2e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily CH PF00307.26 EPE27826.1 - 3.9e-60 200.5 0.0 2.6e-16 59.5 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EPE27826.1 - 1.5e-06 28.2 0.2 3.5e-05 23.8 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EPE27826.1 - 0.00087 18.4 1.5 0.12 11.7 0.2 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EPE27826.1 - 0.038 13.8 4.5 0.049 13.5 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain CAMSAP_CH PF11971.3 EPE27826.1 - 0.13 11.8 0.0 38 4.0 0.0 3.2 3 0 0 3 3 3 0 CAMSAP CH domain EF-hand_5 PF13202.1 EPE27826.1 - 0.46 9.9 3.0 0.38 10.1 0.2 2.4 2 0 0 2 2 2 0 EF hand HCMVantigenic_N PF12154.3 EPE27826.1 - 2.4 8.1 6.7 6.1 6.8 0.3 2.4 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV MBOAT PF03062.14 EPE27827.1 - 1.5e-31 109.7 13.9 1.5e-31 109.7 9.6 2.4 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EPE27827.1 - 0.00021 21.2 0.6 0.00055 19.9 0.4 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Plasmid_RAQPRD PF09686.5 EPE27827.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) MIT PF04212.13 EPE27829.1 - 1e-11 44.5 0.4 2.8e-11 43.1 0.3 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DDHD PF02862.12 EPE27830.1 - 2.9e-70 236.6 0.1 5.9e-69 232.3 0.0 2.6 2 0 0 2 2 2 1 DDHD domain RRM_1 PF00076.17 EPE27831.1 - 3.1e-12 45.9 0.0 4.3e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE27831.1 - 2.1e-08 34.0 0.0 3.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE27831.1 - 3.6e-07 29.9 0.0 5.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPE27831.1 - 0.00059 19.5 0.0 0.00087 19.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.22 EPE27832.1 - 6.5e-74 243.7 4.1 4e-25 87.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 EPE27833.1 - 3.3e-25 88.9 0.0 3.3e-25 88.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 FtsJ PF01728.14 EPE27834.1 - 1.7e-60 204.0 0.0 2.1e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EPE27834.1 - 4e-05 23.3 0.0 0.00019 21.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE27834.1 - 0.0073 16.8 0.0 0.03 14.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE27834.1 - 0.01 15.4 0.0 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain OST3_OST6 PF04756.8 EPE27836.1 - 2.2e-19 69.6 0.4 3.1e-19 69.1 0.3 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EPE27836.1 - 0.0095 15.6 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HXXEE PF13787.1 EPE27836.1 - 0.012 15.9 0.7 0.027 14.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif NmrA PF05368.8 EPE27837.1 - 4.4e-19 68.6 0.0 6.9e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE27837.1 - 2e-08 34.4 0.0 2.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EPE27837.1 - 0.033 14.5 0.1 0.094 13.0 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain HIT PF01230.18 EPE27838.1 - 3.2e-24 85.2 0.0 5.1e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPE27838.1 - 7.5e-07 29.3 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding WSC PF01822.14 EPE27839.1 - 1.3e-59 198.0 75.4 5.4e-18 64.7 6.2 5.6 6 0 0 6 6 6 4 WSC domain PQQ_3 PF13570.1 EPE27839.1 - 5.3e-05 23.3 1.6 0.34 11.2 0.0 4.2 4 0 0 4 4 4 2 PQQ-like domain Cys_Met_Meta_PP PF01053.15 EPE27840.1 - 7.9e-32 109.9 0.0 1.1e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPE27840.1 - 4.5e-05 22.5 0.0 0.00015 20.8 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II AMP-binding PF00501.23 EPE27841.1 - 1.6e-80 270.5 0.0 2.3e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPE27841.1 - 1.7e-41 141.8 0.0 3.2e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EPE27841.1 - 1.1e-06 28.2 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EPE27841.1 - 3.6e-05 24.6 0.0 0.00011 23.0 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EPE27841.1 - 6.3e-05 23.1 0.1 0.00017 21.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EPE27841.1 - 0.00022 20.0 0.2 0.0012 17.6 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPE27841.1 - 0.0022 18.0 3.1 0.098 12.6 0.8 2.9 2 1 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EPE27841.1 - 0.0048 17.1 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EPE27841.1 - 0.028 14.3 0.8 0.11 12.3 0.1 2.4 2 0 0 2 2 2 0 short chain dehydrogenase FrhB_FdhB_N PF04422.8 EPE27841.1 - 0.031 14.1 0.2 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term FAD_binding_4 PF01565.18 EPE27842.1 - 1.5e-23 82.7 1.9 2.7e-23 81.9 1.0 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPE27842.1 - 3.4e-12 46.0 0.2 9.9e-12 44.5 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.11 EPE27843.1 - 5.4e-25 87.8 7.4 6e-25 87.6 5.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.10 EPE27843.1 - 3.2e-05 22.8 1.7 3.6e-05 22.6 1.2 1.2 1 0 0 1 1 1 1 PUCC protein Sugar_tr PF00083.19 EPE27843.1 - 0.00013 20.6 2.2 0.00017 20.3 1.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF791 PF05631.9 EPE27843.1 - 0.00063 18.5 0.2 0.00075 18.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_2 PF13347.1 EPE27843.1 - 0.0013 17.2 2.8 0.0015 16.9 1.9 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_3 PF05977.8 EPE27843.1 - 0.0018 16.4 4.6 0.0022 16.1 3.2 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 EPE27843.1 - 0.0076 14.3 0.5 0.01 13.9 0.3 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EPE27844.1 - 2.1e-09 36.5 20.8 3.8e-09 35.7 14.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Ion_trans_2 PF07885.11 EPE27844.1 - 3.7 7.3 10.6 6.4 6.5 0.7 3.0 2 1 0 2 2 2 0 Ion channel DUF2374 PF09574.5 EPE27844.1 - 6.4 6.4 10.5 1.7 8.3 4.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) DUF3114 PF11311.3 EPE27845.1 - 0.046 13.0 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) DUF4098 PF13345.1 EPE27847.1 - 0.056 13.4 11.3 0.64 10.0 0.1 4.5 5 1 0 5 5 5 0 Domain of unknown function (DUF4098) VID27 PF08553.5 EPE27848.1 - 0 1116.2 0.0 0 1116.1 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Mg_trans_NIPA PF05653.9 EPE27850.1 - 4.8e-91 304.8 14.9 2.8e-89 299.0 10.3 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EPE27850.1 - 1.5e-07 31.6 1.8 1.5e-07 31.6 1.2 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EPE27850.1 - 2.5e-05 24.2 6.0 2.5e-05 24.2 4.1 3.7 2 1 0 3 3 3 2 EamA-like transporter family DNA_methylase PF00145.12 EPE27851.1 - 2.2e-33 115.7 0.0 7.5e-33 114.0 0.0 1.9 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EPE27851.1 - 2.6e-07 30.4 0.2 0.0006 19.5 0.0 2.4 2 0 0 2 2 2 2 BAH domain DUF3602 PF12223.3 EPE27852.1 - 0.14 12.5 5.1 0.44 10.9 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3602) WD40 PF00400.27 EPE27854.1 - 5.7e-14 51.3 13.3 0.00027 20.7 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat YL1 PF05764.8 EPE27854.1 - 3 7.3 11.9 5.8 6.4 8.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein GRAM PF02893.15 EPE27855.1 - 1.2e-26 91.9 1.1 1.3e-14 53.3 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 EPE27855.1 - 2e-25 89.1 0.0 1.1e-24 86.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 EPE27855.1 - 8.3e-14 51.6 0.1 4.2e-13 49.3 0.0 2.3 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 EPE27855.1 - 2.3e-05 24.6 0.1 9.1e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EPE27855.1 - 0.00012 22.0 0.0 0.00036 20.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 EPE27855.1 - 0.00029 19.5 0.0 0.00047 18.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase NIF PF03031.13 EPE27856.1 - 4.2e-29 101.2 0.0 9.1e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EPE27856.1 - 2.7e-09 36.7 0.3 6.5e-09 35.5 0.2 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EPE27856.1 - 1.7e-08 34.4 0.3 1.7e-07 31.2 0.0 2.8 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain GRIM-19 PF06212.7 EPE27857.1 - 1e-22 80.2 0.0 1.8e-22 79.4 0.0 1.4 1 1 0 1 1 1 1 GRIM-19 protein Sigma70_r1_2 PF00140.15 EPE27857.1 - 0.083 12.5 1.4 0.17 11.5 0.1 1.9 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 DUF1358 PF07096.6 EPE27857.1 - 0.15 11.7 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) adh_short PF00106.20 EPE27858.1 - 6.5e-17 61.9 0.0 8.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE27858.1 - 3.6e-15 56.4 0.0 5.2e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE27858.1 - 2.9e-07 30.3 0.0 3.9e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE27858.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 EPE27859.1 - 1e-29 102.4 0.2 2.5e-29 101.2 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE27859.1 - 1.7e-20 72.8 0.4 1.7e-20 72.8 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EPE27859.1 - 0.00048 19.7 0.4 0.00084 18.9 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EPE27859.1 - 0.0051 16.2 0.2 0.0084 15.5 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EPE27859.1 - 0.011 15.3 0.3 0.023 14.3 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain STAS_2 PF13466.1 EPE27859.1 - 0.044 13.8 0.1 3.9 7.5 0.0 2.3 2 0 0 2 2 2 0 STAS domain PALP PF00291.20 EPE27859.1 - 0.058 12.6 1.3 0.17 11.0 1.1 1.6 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme HI0933_like PF03486.9 EPE27859.1 - 0.061 11.7 0.4 0.085 11.3 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 EPE27859.1 - 0.066 12.3 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EPE27859.1 - 0.07 13.7 0.0 0.14 12.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox PF00070.22 EPE27859.1 - 0.073 13.4 1.0 1.1 9.6 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 EPE27859.1 - 0.1 12.8 0.1 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain Epimerase PF01370.16 EPE27860.1 - 6.3e-09 35.6 0.0 0.0005 19.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EPE27860.1 - 1.9e-08 34.6 0.1 1e-07 32.2 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EPE27860.1 - 3.3e-07 29.2 0.0 0.0028 16.4 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EPE27860.1 - 1e-05 24.9 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EPE27860.1 - 4.4e-05 22.5 0.0 0.00047 19.1 0.0 2.4 2 1 1 3 3 3 1 Male sterility protein Acetyltransf_13 PF13880.1 EPE27861.1 - 3.7e-12 45.8 0.0 9.5e-12 44.4 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EPE27861.1 - 3.2e-11 42.6 1.3 7.2e-11 41.4 0.9 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EPE27861.1 - 0.0051 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ADK_lid PF05191.9 EPE27861.1 - 0.07 12.8 0.1 0.3 10.7 0.3 2.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid Fungal_trans_2 PF11951.3 EPE27863.1 - 3.5e-37 127.9 0.0 4.6e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE27863.1 - 6.3e-10 38.8 11.2 1.1e-09 38.0 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1890 PF09001.6 EPE27863.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) Trypan_PARP PF05887.6 EPE27863.1 - 0.62 9.8 5.0 0.96 9.2 2.2 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) AT_hook PF02178.14 EPE27863.1 - 1.3 8.8 10.1 4.8 7.2 7.0 2.0 1 0 0 1 1 1 0 AT hook motif ABC_tran PF00005.22 EPE27864.1 - 2e-50 170.6 0.1 3.4e-24 85.6 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EPE27864.1 - 1.5e-42 145.1 40.5 1e-27 96.6 6.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.1 EPE27864.1 - 4.7e-17 62.8 1.9 0.00073 19.5 0.0 4.2 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 EPE27864.1 - 1.7e-08 33.9 0.5 0.00065 18.9 0.1 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EPE27864.1 - 7.1e-08 32.0 0.1 0.0094 15.3 0.0 3.2 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 EPE27864.1 - 9.6e-08 31.3 1.0 0.0055 15.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPE27864.1 - 1.5e-07 30.8 2.2 0.0061 16.0 0.7 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EPE27864.1 - 1.5e-07 31.5 0.7 0.0047 16.9 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 EPE27864.1 - 2e-07 30.4 0.0 0.2 10.6 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain AAA_23 PF13476.1 EPE27864.1 - 2.8e-07 31.0 0.1 0.002 18.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EPE27864.1 - 4.2e-07 29.6 0.8 0.0017 17.9 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.1 EPE27864.1 - 8.1e-07 29.2 0.8 0.016 15.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 EPE27864.1 - 4.1e-06 26.5 0.0 0.042 13.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain SbcCD_C PF13558.1 EPE27864.1 - 6.2e-06 26.0 1.2 0.17 11.8 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 EPE27864.1 - 2e-05 23.6 0.8 0.027 13.3 0.1 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_28 PF13521.1 EPE27864.1 - 2.6e-05 24.2 0.7 0.089 12.7 0.5 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EPE27864.1 - 3.2e-05 24.7 0.0 0.61 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EPE27864.1 - 5.8e-05 22.7 0.4 0.06 12.9 0.1 2.8 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EPE27864.1 - 0.00011 21.9 0.1 0.053 13.2 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_19 PF13245.1 EPE27864.1 - 0.00019 21.1 0.1 0.2 11.4 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EPE27864.1 - 0.00026 20.7 0.2 1.3 8.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) cobW PF02492.14 EPE27864.1 - 0.00056 19.3 3.1 0.37 10.2 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EPE27864.1 - 0.0006 19.9 0.1 0.93 9.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.2 EPE27864.1 - 0.0008 18.9 5.6 0.23 10.8 0.6 2.3 2 0 0 2 2 2 2 AAA-like domain UPF0079 PF02367.12 EPE27864.1 - 0.00094 18.8 0.6 1.7 8.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EPE27864.1 - 0.00096 19.3 0.1 3.4 7.8 0.1 3.4 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EPE27864.1 - 0.0015 19.0 0.1 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 EPE27864.1 - 0.0018 17.9 0.3 1.3 8.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EPE27864.1 - 0.0019 17.7 1.0 0.52 9.8 0.3 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Pox_A32 PF04665.7 EPE27864.1 - 0.002 17.4 1.3 0.77 9.0 0.2 2.2 2 0 0 2 2 2 2 Poxvirus A32 protein AAA_33 PF13671.1 EPE27864.1 - 0.0022 17.8 0.1 2.6 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPE27864.1 - 0.0027 17.4 0.3 2.8 7.6 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EPE27864.1 - 0.0028 17.9 0.1 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EPE27864.1 - 0.004 16.8 0.4 0.57 9.8 0.2 3.2 4 0 0 4 4 4 1 NTPase MMR_HSR1 PF01926.18 EPE27864.1 - 0.0043 16.9 0.4 4.4 7.2 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EPE27864.1 - 0.012 15.5 0.1 6.3 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EPE27864.1 - 0.014 14.6 0.4 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.12 EPE27864.1 - 0.02 14.3 0.1 4.7 6.5 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein G-alpha PF00503.15 EPE27864.1 - 0.022 13.4 0.1 4 6.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Septin PF00735.13 EPE27864.1 - 0.03 13.3 0.8 3.2 6.6 0.1 2.3 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.7 EPE27864.1 - 0.033 13.2 1.1 4.8 6.2 0.3 2.4 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.13 EPE27864.1 - 0.035 13.6 0.3 2.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.20 EPE27864.1 - 0.035 13.6 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PDR_CDR PF06422.7 EPE27864.1 - 0.083 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 CDR ABC transporter KAP_NTPase PF07693.9 EPE27864.1 - 0.088 11.7 0.0 9.1 5.1 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain SRP54 PF00448.17 EPE27864.1 - 0.1 12.0 0.7 11 5.4 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PIF1 PF05970.9 EPE27864.1 - 0.19 10.6 0.3 3.4 6.5 0.1 2.3 2 0 0 2 2 2 0 PIF1-like helicase PduV-EutP PF10662.4 EPE27864.1 - 0.24 10.8 0.4 14 5.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EPE27864.1 - 0.27 10.4 0.5 8.8 5.5 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF2075 PF09848.4 EPE27864.1 - 0.3 10.0 0.2 9 5.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MFS_1 PF07690.11 EPE27865.1 - 4e-52 177.0 11.9 4e-52 177.0 8.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE27865.1 - 2.9e-06 26.1 9.1 2.9e-06 26.1 6.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EPE27865.1 - 3.1e-05 22.3 4.1 6.1e-05 21.4 2.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EPE27865.1 - 0.0085 14.8 1.5 0.014 14.1 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) OATP PF03137.15 EPE27865.1 - 0.65 7.9 11.9 0.0089 14.1 1.8 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Neil1-DNA_bind PF09292.5 EPE27866.1 - 0.079 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind Syntaxin-18_N PF10496.4 EPE27867.1 - 5e-17 61.5 0.9 1.6e-16 59.9 0.1 2.3 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EPE27867.1 - 0.00022 20.8 2.6 0.00022 20.8 1.8 2.4 3 0 0 3 3 3 1 SNARE domain HTH_33 PF13592.1 EPE27867.1 - 0.0086 15.5 0.6 0.18 11.3 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix Syntaxin PF00804.20 EPE27867.1 - 0.009 16.1 0.7 0.009 16.1 0.5 3.1 2 1 0 3 3 3 1 Syntaxin Sec20 PF03908.8 EPE27867.1 - 0.023 14.3 2.7 0.043 13.5 0.1 2.6 2 1 0 2 2 2 0 Sec20 DUF16 PF01519.11 EPE27867.1 - 0.86 9.8 8.9 3 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 TipAS PF07739.8 EPE27867.1 - 0.99 9.7 5.6 1.8 8.9 0.6 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain IL3 PF02059.10 EPE27867.1 - 2.3 8.2 8.0 3.6 7.6 0.1 3.2 3 1 0 3 3 3 0 Interleukin-3 LXG PF04740.7 EPE27867.1 - 3.8 7.2 12.1 4.3 7.0 2.6 3.1 3 0 0 3 3 3 0 LXG domain of WXG superfamily Caudo_TAP PF02413.12 EPE27867.1 - 7.3 6.7 9.5 0.65 10.1 0.3 3.0 2 1 1 3 3 3 0 Caudovirales tail fibre assembly protein Aminotran_1_2 PF00155.16 EPE27868.1 - 8e-84 281.6 0.0 9.2e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Chitin_synth_2 PF03142.10 EPE27869.1 - 1.1e-229 763.2 0.0 1.5e-229 762.8 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EPE27869.1 - 6e-63 212.9 0.0 8.3e-62 209.2 0.0 2.4 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 EPE27869.1 - 9.5e-16 58.0 3.2 9.5e-16 58.0 2.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 EPE27869.1 - 1.5e-15 56.7 0.0 8.3e-09 35.1 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EPE27869.1 - 1.3e-13 51.3 0.0 5.4e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 EPE27869.1 - 1.7e-12 46.8 1.2 1.2e-11 44.2 0.7 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 EPE27869.1 - 1.1e-05 24.7 0.0 2.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EPE27869.1 - 0.00061 19.5 0.0 0.037 13.7 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 EPE27870.1 - 7e-253 839.8 1.4 1.1e-252 839.1 1.0 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EPE27870.1 - 1.5e-171 571.9 0.0 2e-171 571.4 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EPE27870.1 - 3e-23 81.4 0.0 1.6e-14 53.4 0.0 2.8 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EPE27870.1 - 3.7e-17 61.8 2.0 1.7e-16 59.7 1.0 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EPE27870.1 - 2.6e-15 56.8 0.5 5.1e-12 46.0 0.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EPE27870.1 - 4.6e-15 55.8 3.6 4.6e-15 55.8 2.5 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EPE27870.1 - 0.0002 21.0 0.0 0.031 13.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 EPE27870.1 - 0.0011 19.0 0.1 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Glyco_transf_21 PF13506.1 EPE27870.1 - 0.0082 15.4 0.0 0.029 13.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 21 AAA_22 PF13401.1 EPE27870.1 - 0.013 15.6 0.1 0.043 13.9 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EPE27870.1 - 0.039 13.3 0.4 2 7.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EPE27870.1 - 0.045 13.2 0.1 0.16 11.5 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EPE27870.1 - 0.078 12.6 0.1 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2592 PF10766.4 EPE27870.1 - 0.091 12.1 1.1 0.33 10.3 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) SRPRB PF09439.5 EPE27870.1 - 0.13 11.5 0.4 2.2 7.4 0.3 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPE27870.1 - 0.17 10.9 0.1 0.37 9.9 0.1 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NIR_SIR PF01077.17 EPE27871.1 - 6.4e-53 178.3 0.3 7.6e-46 155.3 0.0 2.7 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EPE27871.1 - 1.7e-30 104.4 0.0 7.4e-15 54.3 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EPE27871.1 - 7e-27 94.1 0.0 2e-26 92.6 0.0 1.9 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EPE27871.1 - 1.2e-08 34.7 0.1 2.6e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Death PF00531.17 EPE27871.1 - 0.017 14.8 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 Death domain Kei1 PF08552.6 EPE27872.1 - 9.3e-57 191.7 4.6 1.2e-56 191.4 3.2 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Ras PF00071.17 EPE27873.1 - 6.6e-52 175.1 0.1 8.7e-52 174.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE27873.1 - 5.7e-15 55.8 0.1 1.1e-14 54.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPE27873.1 - 1.1e-13 50.7 0.2 1.5e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EPE27873.1 - 8.6e-05 22.4 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPE27873.1 - 0.00043 19.5 0.0 0.00067 18.9 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EPE27873.1 - 0.00082 18.8 0.0 0.0046 16.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPE27873.1 - 0.00092 18.4 0.1 0.0018 17.4 0.0 1.5 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EPE27873.1 - 0.074 13.1 0.0 2.3 8.3 0.0 2.6 1 1 1 2 2 2 0 AAA domain Nop53 PF07767.6 EPE27874.1 - 4.3e-108 361.7 23.9 5.2e-108 361.4 16.6 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Peptidase_C12 PF01088.16 EPE27876.1 - 6.4e-53 179.1 0.0 7.5e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 EMP70 PF02990.11 EPE27877.1 - 6.2e-165 549.5 1.1 1.7e-164 548.1 0.8 1.7 1 1 0 1 1 1 1 Endomembrane protein 70 Pex2_Pex12 PF04757.9 EPE27878.1 - 2.8e-55 187.2 0.3 9.3e-55 185.5 0.5 1.6 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EPE27878.1 - 3.1e-06 27.1 2.4 5.4e-06 26.3 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE27878.1 - 0.00071 19.3 2.0 0.0011 18.7 1.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EPE27878.1 - 0.0045 16.8 2.0 0.0077 16.0 1.4 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EPE27878.1 - 0.0095 15.5 1.4 0.015 14.9 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE27878.1 - 0.014 15.0 3.9 0.023 14.3 2.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_16 PF00722.16 EPE27879.1 - 2.6e-42 144.2 3.2 5.5e-42 143.1 2.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ApoM PF11032.3 EPE27880.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 1 0 1 1 1 0 Apolipoprotein M (ApoM) Thaumatin PF00314.12 EPE27880.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Thaumatin family DPM3 PF08285.6 EPE27881.1 - 0.28 11.0 4.0 0.59 10.0 0.4 2.3 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) CutC PF03932.9 EPE27883.1 - 9.8e-45 152.2 0.0 1.4e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 CutC family BtpA PF03437.10 EPE27883.1 - 0.11 11.7 0.3 0.38 9.9 0.0 1.9 2 0 0 2 2 2 0 BtpA family PRAI PF00697.17 EPE27883.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase APH PF01636.18 EPE27885.1 - 1.1e-15 58.0 0.0 1.6e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE27885.1 - 3.2e-09 36.6 0.0 4.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPE27885.1 - 5.2e-05 22.5 0.0 8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pyridox_ox_2 PF12900.2 EPE27886.1 - 3.6e-38 130.6 0.0 5e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase APC8 PF04049.8 EPE27887.1 - 1.6e-36 125.1 0.2 4.5e-35 120.4 0.0 2.5 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 EPE27887.1 - 2.9e-17 62.0 12.0 3.4e-06 26.5 0.1 6.9 5 1 2 7 7 7 3 TPR repeat TPR_1 PF00515.23 EPE27887.1 - 1.3e-15 56.2 10.5 0.00057 19.3 0.0 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPE27887.1 - 4.2e-12 44.9 22.6 0.1 12.5 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPE27887.1 - 4e-10 39.4 17.6 0.015 15.2 1.1 6.9 5 1 2 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EPE27887.1 - 7.3e-10 38.8 6.5 0.059 13.5 0.2 5.4 5 1 1 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EPE27887.1 - 1.9e-09 36.6 9.3 0.00026 20.5 0.0 6.3 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPE27887.1 - 2e-08 33.9 9.8 0.0016 18.2 0.1 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPE27887.1 - 2.1e-08 34.0 11.6 0.025 15.1 0.0 7.9 6 1 3 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPE27887.1 - 2.6e-08 34.2 15.3 1.8e-05 25.2 0.5 6.5 6 1 2 8 8 6 1 Tetratricopeptide repeat DUF3856 PF12968.2 EPE27887.1 - 1.8e-05 24.6 1.9 0.0061 16.3 0.1 2.8 1 1 1 2 2 2 2 Domain of Unknown Function (DUF3856) TPR_7 PF13176.1 EPE27887.1 - 0.00072 19.1 12.8 0.54 10.1 0.0 5.9 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPE27887.1 - 0.0046 17.2 7.9 13 6.2 0.1 5.9 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPE27887.1 - 0.0066 16.5 6.3 2.6 8.4 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2424 PF10340.4 EPE27887.1 - 0.048 12.2 0.0 0.088 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) MIT PF04212.13 EPE27887.1 - 0.073 12.9 0.1 0.38 10.6 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 EPE27887.1 - 0.13 12.7 20.7 75 4.1 0.1 8.8 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_15 PF13429.1 EPE27887.1 - 4.4 6.2 11.3 0.18 10.8 2.0 2.8 4 1 0 4 4 4 0 Tetratricopeptide repeat polyprenyl_synt PF00348.12 EPE27888.1 - 4e-72 242.2 0.0 4.8e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CaKB PF03185.10 EPE27889.1 - 0.092 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Ycf66_N PF07444.6 EPE27889.1 - 0.49 10.1 5.1 0.43 10.3 0.5 2.6 2 0 0 2 2 2 0 Ycf66 protein N-terminus Subtilosin_A PF11420.3 EPE27890.1 - 2.5 8.1 4.3 0.74 9.8 0.6 1.8 2 0 0 2 2 2 0 Bacteriocin subtilosin A DUF1996 PF09362.5 EPE27891.1 - 1.2e-90 303.3 0.7 1.4e-90 303.0 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Cation_efflux PF01545.16 EPE27892.1 - 1.2e-32 113.1 5.3 1.6e-32 112.7 3.7 1.1 1 0 0 1 1 1 1 Cation efflux family TMEM223 PF14640.1 EPE27894.1 - 0.068 13.1 0.2 0.097 12.6 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 Spherulin4 PF12138.3 EPE27895.1 - 1.2e-55 188.7 0.0 1.3e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Glyco_hydro_114 PF03537.8 EPE27896.1 - 1.8e-21 75.7 0.0 3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 SEP PF08059.8 EPE27898.1 - 5.3e-26 90.7 0.0 1.2e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 EPE27898.1 - 1.9e-12 46.4 0.6 3e-12 45.8 0.4 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EPE27898.1 - 6.2e-12 45.4 0.0 1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 UBX domain TOM13 PF08219.6 EPE27899.1 - 6.2e-30 102.7 0.0 7.8e-30 102.4 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.15 EPE27900.1 - 3.3e-29 101.9 2.8 5.1e-29 101.3 1.9 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein DUF1996 PF09362.5 EPE27901.1 - 3.1e-76 256.1 0.0 4.4e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gtr1_RagA PF04670.7 EPE27902.1 - 6.6e-91 303.5 0.2 8.8e-91 303.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EPE27902.1 - 1e-07 31.3 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EPE27902.1 - 5.7e-07 29.0 0.1 9.8e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE27902.1 - 4.6e-06 27.1 0.0 1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPE27902.1 - 6.6e-06 26.0 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EPE27902.1 - 0.0014 18.1 0.3 0.0073 15.8 0.2 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EPE27902.1 - 0.0042 17.3 0.6 0.011 16.0 0.4 2.0 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.8 EPE27902.1 - 0.021 13.7 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EPE27902.1 - 0.063 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 EPE27902.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HATPase_c_4 PF13749.1 EPE27902.1 - 0.083 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal G-alpha PF00503.15 EPE27902.1 - 0.15 10.7 3.6 0.59 8.7 0.7 2.2 1 1 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.4 EPE27902.1 - 0.15 11.5 0.2 0.78 9.2 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PAS_9 PF13426.1 EPE27903.1 - 7.6e-18 64.8 0.0 1.5e-15 57.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EPE27903.1 - 4.4e-06 26.4 0.0 1.5e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 PAS fold Cutinase PF01083.17 EPE27904.1 - 3.2e-51 173.6 11.2 3.6e-51 173.4 7.8 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EPE27904.1 - 0.0025 17.2 0.2 0.0043 16.4 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EPE27904.1 - 0.029 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_1 PF00561.15 EPE27904.1 - 0.05 13.1 0.1 0.073 12.6 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE27904.1 - 0.17 11.6 1.5 0.25 11.0 0.9 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.9 EPE27905.1 - 1.8e-65 220.7 0.0 2.6e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 EPE27905.1 - 9.8e-09 34.3 80.7 7.8e-08 31.4 33.3 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 EPE27905.1 - 0.038 13.7 4.5 0.15 11.8 0.2 3.2 3 0 0 3 3 3 0 MFS_1 like family Peptidase_M24 PF00557.19 EPE27906.1 - 4e-43 147.4 0.2 5.2e-43 147.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 SPT6_acidic PF14632.1 EPE27906.1 - 0.16 12.1 3.6 0.31 11.2 2.5 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Mgm101p PF06420.7 EPE27906.1 - 0.45 9.8 1.7 4.2 6.6 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial genome maintenance MGM101 HET PF06985.6 EPE27907.1 - 1e-21 77.5 0.0 1.9e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kdo PF06293.9 EPE27908.1 - 2.2e-06 26.8 0.0 3.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EPE27908.1 - 0.045 12.8 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain RNase_H PF00075.19 EPE27909.1 - 4.7e-05 23.7 0.0 5.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EPE27909.1 - 0.0021 17.8 0.0 0.008 15.9 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase-like Fungal_lectin PF07938.7 EPE27910.1 - 3.2e-07 29.9 0.7 4.5e-07 29.4 0.5 1.2 1 0 0 1 1 1 1 Fungal fucose-specific lectin Glyco_hydro_47 PF01532.15 EPE27911.1 - 8.2e-165 548.8 0.0 9.4e-165 548.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HET PF06985.6 EPE27912.1 - 2.6e-22 79.4 0.0 6.2e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1546 PF07571.8 EPE27913.1 - 4.3e-31 106.8 0.0 1.3e-30 105.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EPE27913.1 - 3.4e-20 71.7 0.1 7e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EPE27913.1 - 0.031 14.3 0.1 0.053 13.6 0.1 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Ufd2P_core PF10408.4 EPE27913.1 - 0.17 10.0 0.0 0.24 9.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin elongating factor core Thymidylate_kin PF02223.12 EPE27914.1 - 1.7e-32 112.3 0.0 2.1e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase Methyltransf_24 PF13578.1 EPE27914.1 - 0.094 13.5 0.0 0.38 11.5 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain GTP_cyclohydroI PF01227.17 EPE27915.1 - 5.3e-73 244.1 0.1 7.1e-73 243.6 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EPE27915.1 - 0.0033 17.3 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein CDC45 PF02724.9 EPE27915.1 - 7.4 4.4 13.2 9.6 4.0 9.2 1.2 1 0 0 1 1 1 0 CDC45-like protein TAFII28 PF04719.9 EPE27916.1 - 3.6e-19 68.3 0.0 1.1e-17 63.5 0.0 2.3 1 1 0 1 1 1 1 hTAFII28-like protein conserved region DUF566 PF04484.7 EPE27916.1 - 0.79 9.1 9.8 1.1 8.7 6.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF500 PF04366.7 EPE27917.1 - 2.4e-41 140.1 0.0 3.6e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Glyco_hydro_3 PF00933.16 EPE27918.1 - 3.5e-82 275.7 0.0 5.2e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE27918.1 - 3.5e-46 157.5 0.2 8.2e-46 156.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE27918.1 - 8.4e-21 73.6 0.0 1.5e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain NUDIX PF00293.23 EPE27920.1 - 3.4e-06 26.7 0.0 5.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain F-box PF00646.28 EPE27922.1 - 0.005 16.4 0.0 0.005 16.4 0.0 2.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EPE27922.1 - 0.096 12.4 0.5 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 F-box-like DUF3632 PF12311.3 EPE27923.1 - 2.9e-25 89.1 0.1 4.2e-25 88.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) p450 PF00067.17 EPE27925.1 - 3.7e-51 174.0 0.0 4.9e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_Tnp_IS1595 PF12762.2 EPE27925.1 - 0.091 12.5 0.2 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 ISXO2-like transposase domain HeLo PF14479.1 EPE27926.1 - 2.5e-34 118.8 0.1 3.7e-34 118.3 0.1 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation UQ_con PF00179.21 EPE27926.1 - 2e-23 82.3 0.0 6.8e-23 80.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Zn_clus PF00172.13 EPE27926.1 - 0.32 10.9 7.0 0.86 9.5 4.8 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sdh_cyt PF01127.17 EPE27927.1 - 7.9e-24 83.8 2.9 1.1e-23 83.3 2.0 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sugar_tr PF00083.19 EPE27928.1 - 4e-126 421.2 29.2 4.9e-126 420.9 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE27928.1 - 2.3e-17 62.7 37.6 2.3e-17 62.7 26.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_1 PF00232.13 EPE27929.1 - 4.4e-98 328.4 0.7 5.5e-98 328.1 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 TGT PF01702.13 EPE27930.1 - 1.4e-37 129.2 0.0 2.1e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase HET PF06985.6 EPE27931.1 - 1.1e-22 80.7 0.0 2.1e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EPE27933.1 - 5.8e-30 104.2 0.0 1.3e-29 103.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_28 PF13521.1 EPE27934.1 - 1.2e-26 93.5 0.0 1.4e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPE27934.1 - 6.8e-05 22.7 0.0 0.0097 15.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EPE27934.1 - 0.00057 19.8 0.1 0.00074 19.4 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EPE27934.1 - 0.00062 19.7 0.2 0.0012 18.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EPE27934.1 - 0.0024 18.1 0.0 0.0045 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_32 PF13654.1 EPE27934.1 - 0.013 14.1 0.0 0.025 13.2 0.0 1.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EPE27934.1 - 0.014 15.0 0.2 0.045 13.4 0.1 1.9 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EPE27934.1 - 0.016 14.6 0.0 0.06 12.7 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EPE27934.1 - 0.017 15.9 0.1 0.049 14.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EPE27934.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EPE27934.1 - 0.018 15.4 0.1 0.029 14.8 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 EPE27934.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.17 EPE27934.1 - 0.029 14.5 0.0 0.049 13.8 0.0 1.6 1 1 0 1 1 1 0 RNA helicase Dynamin_N PF00350.18 EPE27934.1 - 0.032 14.0 0.1 0.055 13.2 0.0 1.6 1 1 1 2 2 2 0 Dynamin family AAA_21 PF13304.1 EPE27934.1 - 0.037 14.0 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPE27934.1 - 0.044 13.3 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EPE27934.1 - 0.05 13.9 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EPE27934.1 - 0.054 12.5 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Septin ABC_ATPase PF09818.4 EPE27934.1 - 0.088 11.3 0.1 0.18 10.3 0.0 1.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.13 EPE27934.1 - 0.095 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RdRP PF05183.7 EPE27935.1 - 2.9e-137 458.8 0.0 4.7e-137 458.1 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_12 PF13087.1 EPE27935.1 - 1.7e-48 164.6 0.0 3.7e-48 163.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPE27935.1 - 2.3e-47 161.5 0.7 9e-46 156.3 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE27935.1 - 5e-13 48.6 0.0 3.7e-12 45.8 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EPE27935.1 - 7.8e-13 48.4 0.0 2.3e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 EPE27935.1 - 5e-06 26.2 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Helicase ResIII PF04851.10 EPE27935.1 - 2.2e-05 24.3 0.0 5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EPE27935.1 - 2.6e-05 23.8 0.0 0.63 9.5 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EPE27935.1 - 9.3e-05 21.7 0.0 0.00095 18.4 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.1 EPE27935.1 - 0.00014 21.9 0.1 0.00048 20.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPE27935.1 - 0.00038 20.6 0.0 0.0033 17.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EPE27935.1 - 0.0011 19.2 0.1 0.01 16.0 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 EPE27935.1 - 0.0014 18.0 0.0 0.011 15.1 0.0 2.2 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EPE27935.1 - 0.0073 15.3 0.2 0.068 12.1 0.0 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EPE27935.1 - 0.009 15.5 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 EPE27935.1 - 0.03 14.4 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Arch_ATPase PF01637.13 EPE27935.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 EPE27935.1 - 0.095 12.8 0.0 0.33 11.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EPE27935.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EPE27935.1 - 0.17 11.3 0.0 0.4 10.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein HET PF06985.6 EPE27936.1 - 2e-24 86.3 0.1 3.2e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SF-assemblin PF06705.6 EPE27937.1 - 0.049 12.7 1.1 0.098 11.7 0.3 1.7 1 1 0 1 1 1 0 SF-assemblin/beta giardin SAM_decarbox PF01536.11 EPE27938.1 - 7e-87 291.1 0.0 8.9e-61 205.3 0.0 2.9 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase BTB PF00651.26 EPE27939.1 - 0.0048 16.8 0.0 0.03 14.3 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Ank_2 PF12796.2 EPE27940.1 - 9.2e-11 41.9 0.0 2.2e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE27940.1 - 2.5e-10 40.5 0.0 9.9e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EPE27940.1 - 4.5e-09 35.6 0.0 1.6e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EPE27940.1 - 2.4e-08 33.4 0.0 0.00091 19.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EPE27940.1 - 0.00029 20.9 0.0 0.0017 18.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) ParA PF10609.4 EPE27943.1 - 4.4e-36 122.6 0.2 7.4e-36 121.8 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EPE27943.1 - 2.9e-15 56.1 0.0 4.4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EPE27943.1 - 1.8e-06 27.2 0.0 5e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 EPE27943.1 - 1.3e-05 25.1 0.0 6.5e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EPE27943.1 - 6.4e-05 22.1 1.3 9.5e-05 21.5 0.4 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 EPE27943.1 - 0.0017 17.1 0.2 0.0029 16.4 0.2 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 EPE27943.1 - 0.0035 16.7 0.1 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 EPE27943.1 - 0.016 14.5 0.4 0.027 13.8 0.3 1.5 1 1 0 1 1 1 0 YhjQ protein DUF258 PF03193.11 EPE27943.1 - 0.038 13.1 1.0 0.062 12.4 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_26 PF13500.1 EPE27943.1 - 0.12 11.9 1.5 4.4 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EPE27943.1 - 0.16 11.6 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AA_permease PF00324.16 EPE27944.1 - 2.8e-136 454.6 40.1 3.5e-136 454.3 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE27944.1 - 5.8e-40 137.1 42.7 7.6e-40 136.7 29.6 1.1 1 0 0 1 1 1 1 Amino acid permease XPC-binding PF09280.6 EPE27945.1 - 0.047 13.1 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 XPC-binding domain Hrs_helical PF12210.3 EPE27945.1 - 0.3 11.3 1.4 0.44 10.8 0.3 1.7 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Ribonucleas_3_3 PF14622.1 EPE27946.1 - 3.8e-27 94.7 0.0 7.9e-27 93.7 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EPE27946.1 - 0.00014 22.3 0.0 0.00033 21.0 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain KAT11 PF08214.6 EPE27947.1 - 2.4e-100 336.0 0.0 3.4e-100 335.5 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Frag1 PF10277.4 EPE27948.1 - 0.003 17.0 0.2 0.003 17.0 0.2 1.9 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family RTA1 PF04479.8 EPE27950.1 - 2e-30 105.9 10.0 2.8e-30 105.4 6.9 1.1 1 0 0 1 1 1 1 RTA1 like protein AA_permease_2 PF13520.1 EPE27951.1 - 2.4e-49 168.0 47.4 3e-49 167.7 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE27951.1 - 1.4e-19 69.8 36.0 1.9e-19 69.3 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease E1-E2_ATPase PF00122.15 EPE27952.1 - 1.8e-63 213.6 1.4 3.4e-63 212.7 1.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPE27952.1 - 8.2e-34 116.7 6.2 2.7e-33 115.0 4.3 1.9 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPE27952.1 - 1.7e-31 110.2 0.0 1.3e-29 104.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPE27952.1 - 3.3e-17 62.2 0.0 8.6e-17 60.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPE27952.1 - 1.1e-16 61.5 0.0 2.4e-16 60.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPE27952.1 - 6.3e-16 57.5 1.6 7.3e-16 57.4 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPE27952.1 - 0.00023 20.8 0.2 0.0025 17.4 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HET PF06985.6 EPE27953.1 - 1.1e-28 100.1 0.6 1.7e-28 99.5 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LCCL PF03815.14 EPE27953.1 - 6.9e-20 70.8 0.2 1.4e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 LCCL domain HET PF06985.6 EPE27956.1 - 2.2e-26 92.6 2.6 4.1e-26 91.8 1.8 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTB PF00651.26 EPE27957.1 - 0.0028 17.6 0.0 0.081 12.9 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain TRAM_LAG1_CLN8 PF03798.11 EPE27959.1 - 4.7e-40 137.2 17.0 4.7e-40 137.2 11.8 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EPE27959.1 - 1.4e-14 53.3 0.0 1.4e-14 53.3 0.0 2.4 2 0 0 2 2 2 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 EPE27960.1 - 1.6e-33 115.9 20.0 1.6e-33 115.9 13.9 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EPE27960.1 - 2.1e-22 78.3 0.0 2.1e-22 78.3 0.0 2.2 3 0 0 3 3 3 1 TRAM1-like protein Mito_carr PF00153.22 EPE27961.1 - 1.2e-12 47.3 0.2 0.0054 16.4 0.0 5.0 4 1 0 4 4 4 4 Mitochondrial carrier protein Histone PF00125.19 EPE27962.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EPE27962.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EPE27962.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPE27962.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPE27962.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EPE27962.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Sedlin_N PF04628.8 EPE27963.1 - 3.8e-42 143.2 0.0 4.4e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EPE27963.1 - 0.00088 18.9 0.1 0.021 14.5 0.0 2.1 1 1 1 2 2 2 1 Sybindin-like family DUF331 PF03889.8 EPE27963.1 - 0.065 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function L31 PF09784.4 EPE27964.1 - 3.9e-42 142.5 2.0 4.3e-42 142.3 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 RRM_1 PF00076.17 EPE27965.1 - 1.8e-15 56.3 0.0 2.5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE27965.1 - 1e-11 44.6 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE27965.1 - 2.1e-08 33.8 0.1 3.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.1 EPE27966.1 - 0.21 10.5 7.5 0.38 9.6 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1492 PF07374.6 EPE27966.1 - 0.55 10.3 4.7 0.15 12.1 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) DUF2315 PF10231.4 EPE27968.1 - 0.14 12.0 2.6 0.88 9.4 1.8 1.9 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) zf-C2H2_4 PF13894.1 EPE27971.1 - 0.0023 18.1 15.1 0.051 13.9 0.1 5.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE27971.1 - 0.011 15.9 0.0 0.011 15.9 0.0 5.1 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPE27971.1 - 0.013 15.3 6.5 0.24 11.3 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.1 EPE27971.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain IncA PF04156.9 EPE27971.1 - 0.14 11.6 0.4 0.32 10.5 0.3 1.6 1 0 0 1 1 1 0 IncA protein zinc_ribbon_4 PF13717.1 EPE27971.1 - 1.3 8.7 6.6 0.21 11.2 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-met PF12874.2 EPE27971.1 - 1.6 9.0 4.5 32 4.9 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Prok-RING_1 PF14446.1 EPE27971.1 - 2.1 8.1 6.4 3.2 7.5 0.2 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Peptidase_S28 PF05577.7 EPE27972.1 - 8.8e-44 149.7 0.8 2e-42 145.3 0.6 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 RAI16-like PF10257.4 EPE27973.1 - 1.7e-84 283.7 3.1 1.9e-84 283.6 1.4 1.6 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein Adeno_52K PF03052.10 EPE27973.1 - 0.023 13.9 0.1 0.17 11.0 0.0 2.3 1 1 1 2 2 2 0 Adenoviral protein L1 52/55-kDa ABC_tran PF00005.22 EPE27975.1 - 4.1e-46 156.6 0.1 4.7e-26 91.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EPE27975.1 - 2.6e-30 105.6 42.8 4.1e-15 55.6 13.6 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EPE27975.1 - 1.3e-20 74.5 0.6 7.2e-07 29.4 0.0 4.4 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EPE27975.1 - 1.5e-06 27.6 1.4 0.033 13.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EPE27975.1 - 5.5e-06 26.8 3.7 0.052 13.8 0.6 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EPE27975.1 - 8.9e-06 25.0 3.4 0.012 14.8 0.1 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 EPE27975.1 - 1.1e-05 25.0 3.5 0.033 13.9 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain AAA_15 PF13175.1 EPE27975.1 - 0.0001 21.5 0.0 0.78 8.7 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EPE27975.1 - 0.00011 21.4 1.1 0.038 13.1 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EPE27975.1 - 0.00024 20.7 0.2 1.1 8.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EPE27975.1 - 0.0039 16.6 0.5 0.04 13.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EPE27975.1 - 0.0066 16.5 0.1 6.1 7.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 EPE27975.1 - 0.011 15.8 1.0 4 7.6 0.2 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EPE27975.1 - 0.018 14.1 0.3 0.38 9.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.1 EPE27975.1 - 0.032 14.2 1.4 0.9 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EPE27975.1 - 0.046 13.1 1.1 2.1 7.7 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain Rad4 PF03835.10 EPE27975.1 - 0.047 13.1 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain AAA_16 PF13191.1 EPE27975.1 - 0.058 13.3 0.0 7 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.17 EPE27975.1 - 0.1 12.0 2.3 2.5 7.5 0.3 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 EPE27975.1 - 0.14 11.6 2.1 29 4.1 0.0 3.6 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 EPE27975.1 - 0.18 11.4 0.9 14 5.3 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EPE27975.1 - 0.2 11.2 1.4 16 5.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TPR_11 PF13414.1 EPE27976.1 - 3.2e-38 129.1 24.0 2.6e-11 42.9 1.1 7.5 5 2 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 EPE27976.1 - 4.2e-35 117.9 15.3 2e-07 30.2 0.0 8.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 EPE27976.1 - 3.9e-34 113.8 25.7 3.1e-06 26.6 0.0 10.5 11 1 0 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.1 EPE27976.1 - 4.6e-25 85.4 9.8 0.00064 19.3 0.0 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 EPE27976.1 - 8e-22 76.9 21.2 3.8e-05 23.5 0.3 8.1 4 3 4 8 8 7 6 Tetratricopeptide repeat Apc3 PF12895.2 EPE27976.1 - 1.1e-21 76.7 27.3 9.5e-18 64.1 3.2 5.1 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EPE27976.1 - 8.4e-20 70.9 19.4 0.00021 21.8 0.2 7.7 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 EPE27976.1 - 5.9e-15 53.8 6.1 0.48 10.3 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EPE27976.1 - 1.5e-14 53.1 12.7 0.25 12.0 0.2 9.1 6 3 7 13 13 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPE27976.1 - 9.5e-14 51.4 13.8 0.01 16.1 0.0 7.4 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPE27976.1 - 2.6e-13 48.9 14.3 0.13 12.5 0.0 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPE27976.1 - 8.6e-12 44.6 15.4 0.086 13.3 0.3 9.0 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPE27976.1 - 2.9e-06 27.0 4.0 1.2 9.0 0.0 6.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 EPE27976.1 - 0.0068 16.5 0.5 1.6 8.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.7 EPE27976.1 - 0.016 15.8 8.9 9.2 7.0 0.0 5.7 5 0 0 5 5 5 0 Sel1 repeat TPR_10 PF13374.1 EPE27976.1 - 0.93 9.5 8.1 1.2 9.1 0.2 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF788 PF05620.6 EPE27977.1 - 5.6e-42 143.4 0.0 6.2e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF3605 PF12239.3 EPE27978.1 - 1.2e-55 187.7 0.0 1.4e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) NAD_binding_1 PF00175.16 EPE27979.1 - 2.5e-26 92.3 0.0 3.8e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EPE27979.1 - 1.7e-24 85.8 0.0 3e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EPE27979.1 - 1.5e-05 24.9 0.0 0.00073 19.4 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain ATG_C PF09333.6 EPE27980.1 - 3.9e-06 26.9 0.0 0.00039 20.5 0.0 2.6 2 1 0 2 2 2 2 ATG C terminal domain Methyltransf_23 PF13489.1 EPE27981.1 - 5.4e-21 74.9 0.0 9.4e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE27981.1 - 1.9e-09 37.8 0.0 3.9e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE27981.1 - 2.2e-09 37.1 0.0 1.1e-08 34.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE27981.1 - 9.3e-09 35.8 0.0 9e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE27981.1 - 2.4e-06 27.9 0.0 1.5e-05 25.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPE27981.1 - 0.0025 16.9 0.0 0.0049 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EPE27981.1 - 0.031 14.6 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EPE27981.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EPE27981.1 - 0.051 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EPE27981.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF4653 PF15546.1 EPE27981.1 - 0.38 10.0 4.2 0.6 9.3 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Macoilin PF09726.4 EPE27981.1 - 0.66 8.1 2.0 0.88 7.7 1.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Clathrin_lg_ch PF01086.12 EPE27982.1 - 2.7e-71 240.0 6.2 3.2e-71 239.8 4.3 1.0 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.1 EPE27982.1 - 0.14 11.6 0.1 0.29 10.6 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain ATP-synt_B PF00430.13 EPE27982.1 - 1.3 8.8 8.1 1.9 8.3 5.6 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) OmpH PF03938.9 EPE27982.1 - 5.6 6.8 8.7 8.2 6.3 6.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CDC37_N PF03234.9 EPE27983.1 - 1e-53 182.3 6.4 1e-53 182.3 4.4 2.9 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EPE27983.1 - 9.6e-44 148.9 1.5 2.8e-43 147.4 0.1 2.3 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EPE27983.1 - 8.5e-27 92.9 2.1 8.5e-27 92.9 1.5 2.6 3 0 0 3 3 3 1 Cdc37 C terminal domain Cytochrom_B562 PF07361.6 EPE27983.1 - 3 8.3 9.6 3.5 8.1 0.7 4.1 4 0 0 4 4 4 0 Cytochrome b562 ABC_membrane PF00664.18 EPE27984.1 - 1.2e-45 156.1 10.2 1.5e-45 155.7 7.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EPE27984.1 - 2.3e-34 118.6 0.0 7.2e-34 117.0 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EPE27984.1 - 5e-05 22.6 0.0 0.00014 21.1 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE27984.1 - 7.1e-05 22.9 2.0 0.49 10.3 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EPE27984.1 - 0.0009 19.2 0.0 0.0031 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EPE27984.1 - 0.0034 16.8 1.2 0.0062 16.0 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EPE27984.1 - 0.0084 16.2 0.2 0.04 14.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EPE27984.1 - 0.019 14.8 0.8 0.13 12.1 0.5 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EPE27984.1 - 0.04 14.7 0.8 0.12 13.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EPE27984.1 - 0.12 10.9 1.9 0.087 11.3 0.1 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class PH_10 PF15411.1 EPE27986.1 - 7.9e-23 80.8 0.2 1.6e-22 79.8 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EPE27986.1 - 5.7e-10 39.1 0.1 2.3e-09 37.1 0.1 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EPE27986.1 - 2.3e-08 33.7 5.5 4.2e-08 32.8 3.8 1.5 1 0 0 1 1 1 1 Ring finger domain VWA PF00092.23 EPE27986.1 - 2e-07 30.8 0.0 4.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C3HC4_3 PF13920.1 EPE27986.1 - 0.00012 21.6 1.6 0.00021 20.9 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE27986.1 - 0.00025 20.7 5.3 0.00042 19.9 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPE27986.1 - 0.00065 19.6 4.8 0.0012 18.8 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE27986.1 - 0.001 19.1 1.3 0.002 18.2 0.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPE27986.1 - 0.0034 17.0 5.2 0.0062 16.1 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1147 PF06615.6 EPE27986.1 - 0.19 11.5 0.3 0.46 10.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING-like PF08746.6 EPE27986.1 - 0.44 10.5 4.5 0.82 9.7 3.1 1.4 1 0 0 1 1 1 0 RING-like domain DNA_PPF PF02916.10 EPE27987.1 - 0.063 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor Neurochondrin PF05536.6 EPE27988.1 - 6.8e-79 265.6 0.4 1.9e-78 264.1 0.1 1.7 1 1 1 2 2 2 1 Neurochondrin CBF PF03914.12 EPE27988.1 - 0.0069 15.8 0.2 0.018 14.4 0.1 1.7 1 0 0 1 1 1 1 CBF/Mak21 family RIX1 PF08167.7 EPE27988.1 - 0.51 9.9 9.5 0.33 10.6 2.9 3.1 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Voltage_CLC PF00654.15 EPE27989.1 - 2.7e-90 302.9 31.7 2.7e-90 302.9 22.0 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EPE27989.1 - 0.00016 21.3 0.0 0.0076 16.0 0.0 2.4 2 0 0 2 2 2 1 CBS domain Ank_2 PF12796.2 EPE27990.1 - 1.6e-53 178.9 24.2 1.7e-07 31.4 0.0 12.5 7 3 2 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 EPE27990.1 - 3.5e-19 67.5 33.6 0.055 13.3 0.0 17.1 18 1 1 19 19 19 6 Ankyrin repeat Ank_4 PF13637.1 EPE27990.1 - 8.3e-16 58.0 22.1 1.1e-05 25.8 0.0 13.1 10 3 5 15 15 15 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE27990.1 - 5.5e-12 44.6 19.7 0.52 10.7 0.0 17.3 19 1 1 20 20 20 1 Ankyrin repeat Ank_5 PF13857.1 EPE27990.1 - 2.4e-10 40.3 12.1 0.0026 17.9 0.0 10.9 11 1 1 12 12 12 2 Ankyrin repeats (many copies) Glyco_transf_8 PF01501.15 EPE27991.1 - 1.7e-26 93.0 1.5 3e-26 92.2 1.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EPE27991.1 - 0.024 13.9 0.1 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Pkinase PF00069.20 EPE27993.1 - 1.5e-54 184.8 0.0 2.3e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE27993.1 - 4.4e-26 91.5 0.0 6.2e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EPE27993.1 - 5.7e-12 45.5 0.2 2.1e-11 43.7 0.1 2.1 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EPE27993.1 - 0.00043 19.3 0.0 0.0033 16.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPE27993.1 - 0.00049 19.8 0.0 0.0069 16.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EPE27993.1 - 0.00065 18.8 0.0 0.0016 17.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPE27993.1 - 0.042 13.1 0.2 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RNA_pol_I_A49 PF06870.7 EPE27994.1 - 2.3e-71 240.4 2.8 3e-71 240.0 1.9 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF2946 PF11162.3 EPE27995.1 - 0.063 13.4 1.8 0.068 13.3 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Asp PF00026.18 EPE27997.1 - 2.6e-72 243.7 4.8 3.2e-72 243.4 3.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPE27997.1 - 6.6e-11 42.4 3.6 7.4e-11 42.2 0.2 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EPE27997.1 - 8.6e-07 28.6 0.1 2e-06 27.4 0.1 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EPE27997.1 - 4.4e-06 27.0 1.9 0.17 12.3 0.0 4.3 4 1 0 4 4 4 2 Aspartyl protease Pep3_Vps18 PF05131.9 EPE27998.1 - 1.1e-50 170.9 0.0 2.5e-50 169.7 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EPE27998.1 - 4.9e-12 45.6 6.4 6.1e-09 35.6 0.0 3.6 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EPE27998.1 - 5e-05 23.0 0.3 0.00011 22.0 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPE27998.1 - 0.00077 19.1 0.5 0.0015 18.1 0.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF2175 PF09943.4 EPE27998.1 - 0.017 15.1 1.2 0.095 12.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_2 PF13923.1 EPE27998.1 - 0.029 14.3 0.6 0.073 13.1 0.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.4 EPE27998.1 - 0.037 14.1 0.4 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.20 EPE27998.1 - 0.048 13.3 0.3 0.13 11.9 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE27998.1 - 0.079 13.0 0.1 0.23 11.6 0.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger DNA_pol3_theta PF06440.6 EPE27998.1 - 0.12 12.0 0.1 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III, theta subunit Pkinase PF00069.20 EPE28000.1 - 4.8e-68 229.1 0.0 8.7e-68 228.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE28000.1 - 1.6e-49 168.3 0.0 2.5e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EPE28000.1 - 2.3e-26 91.7 0.0 5.2e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EPE28000.1 - 3.4e-17 62.3 0.1 7e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EPE28000.1 - 4.1e-17 61.7 0.2 9.9e-17 60.5 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.18 EPE28000.1 - 2.5e-10 40.7 0.1 4.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 EPE28000.1 - 1.5e-07 30.6 0.0 2.7e-05 23.2 0.0 2.6 3 0 0 3 3 3 1 Kinase-like SAM_PNT PF02198.11 EPE28000.1 - 0.0064 16.2 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 EPE28000.1 - 0.057 13.4 0.6 0.13 12.2 0.4 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Kdo PF06293.9 EPE28000.1 - 0.16 10.9 0.0 0.33 9.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HATPase_c_3 PF13589.1 EPE28001.1 - 7.2e-16 58.0 0.1 2.3e-15 56.4 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EPE28001.1 - 4e-11 42.4 0.0 1.3e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EPE28001.1 - 8.8e-11 41.5 0.2 1.7e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank_2 PF12796.2 EPE28002.1 - 4.2e-34 116.7 2.3 1.3e-12 47.9 0.0 4.7 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPE28002.1 - 1.6e-29 100.2 10.2 1.3e-05 24.7 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 EPE28002.1 - 4.1e-29 100.4 4.1 1.7e-09 37.9 0.0 6.6 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE28002.1 - 3.6e-21 73.1 2.0 0.016 15.3 0.0 7.6 8 0 0 8 8 7 5 Ankyrin repeat Ank_5 PF13857.1 EPE28002.1 - 9.2e-17 60.6 5.4 0.0015 18.6 0.0 6.3 6 1 1 7 7 6 4 Ankyrin repeats (many copies) NACHT PF05729.7 EPE28002.1 - 1.7e-10 40.7 0.1 7.8e-10 38.6 0.0 2.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPE28002.1 - 2.5e-07 30.8 1.5 1.8e-06 28.0 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.17 EPE28002.1 - 1.4e-05 24.1 0.0 2.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EPE28002.1 - 0.00067 19.8 0.0 0.0026 17.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPE28002.1 - 0.0018 18.2 0.7 0.13 12.2 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EPE28002.1 - 0.0048 17.1 0.0 0.014 15.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EPE28002.1 - 0.015 15.4 0.0 0.042 14.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EPE28002.1 - 0.019 14.7 0.0 0.063 13.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Syntaxin_2 PF14523.1 EPE28002.1 - 0.02 14.9 0.1 0.064 13.2 0.1 1.9 1 0 0 1 1 1 0 Syntaxin-like protein Arch_ATPase PF01637.13 EPE28002.1 - 0.046 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase AAA_11 PF13086.1 EPE28002.1 - 0.064 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPE28002.1 - 0.11 12.7 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter tRNA-synt_1 PF00133.17 EPE28003.1 - 2.6e-214 712.6 1.5 1.5e-213 710.1 1.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPE28003.1 - 1.9e-33 115.3 0.1 4.2e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EPE28003.1 - 7e-16 57.8 1.0 1.8e-06 26.8 0.0 4.7 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EPE28003.1 - 6.9e-12 45.0 5.8 3.5e-09 36.2 0.0 3.3 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 EPE28003.1 - 0.0025 17.8 7.3 0.0025 17.8 5.1 2.7 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 EPE28003.1 - 0.011 14.8 0.0 0.093 11.8 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF4028 PF13220.1 EPE28003.1 - 0.074 12.6 1.8 0.32 10.6 1.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) DUF1771 PF08590.5 EPE28004.1 - 3e-13 49.5 10.3 3e-13 49.5 7.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EPE28004.1 - 2e-10 40.7 0.0 8.1e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Smr domain zf-CCCH PF00642.19 EPE28004.1 - 4.8e-07 29.3 0.7 0.0046 16.6 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 EPE28004.1 - 0.058 12.8 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 CUE domain HBS1_N PF08938.5 EPE28004.1 - 0.11 12.6 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 HBS1 N-terminus APH PF01636.18 EPE28005.1 - 1.7e-11 44.3 0.0 2.6e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EPE28005.1 - 0.0063 15.1 0.0 0.0079 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) CTP_synth_N PF06418.9 EPE28006.1 - 6.7e-92 307.4 0.1 9.2e-92 307.0 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EPE28006.1 - 7.5e-56 188.6 0.0 1e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPE28006.1 - 1.6e-06 27.6 0.1 8.2e-06 25.4 0.0 2.2 2 1 0 2 2 2 1 Peptidase C26 DUF1183 PF06682.7 EPE28007.1 - 7.6e-42 144.0 10.1 4.5e-40 138.2 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1183) DnaJ PF00226.26 EPE28008.1 - 1.6e-26 91.8 5.5 2.8e-26 91.0 3.8 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EPE28008.1 - 2.1e-23 81.9 2.3 1.1e-20 73.2 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain PLDc_2 PF13091.1 EPE28009.1 - 1.9e-13 50.2 0.0 5.4e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EPE28009.1 - 2.2e-10 39.9 0.2 0.00032 20.3 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF4660 PF15559.1 EPE28009.1 - 0.096 12.7 0.1 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) NDUFA12 PF05071.11 EPE28010.1 - 1.4e-27 96.1 1.1 1.7e-27 95.9 0.8 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ArgJ PF01960.13 EPE28012.1 - 3.2e-147 490.0 0.0 3.6e-147 489.8 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Pkinase PF00069.20 EPE28013.1 - 6.3e-82 274.6 3.0 5e-39 134.0 0.0 4.6 4 1 0 4 4 4 3 Protein kinase domain HGTP_anticodon2 PF12745.2 EPE28013.1 - 1e-73 247.8 1.3 1e-73 247.8 0.9 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 EPE28013.1 - 4.8e-50 170.0 0.9 9.2e-21 74.0 0.0 3.9 4 0 0 4 4 4 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 EPE28013.1 - 4.9e-14 52.1 0.0 2.8e-13 49.5 0.0 2.3 2 1 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 EPE28013.1 - 7.3e-12 45.1 1.3 1.1e-11 44.5 0.1 2.1 2 0 0 2 2 2 1 RWD domain Kinase-like PF14531.1 EPE28013.1 - 5.5e-06 25.5 0.1 0.17 10.8 0.0 3.3 4 0 0 4 4 4 2 Kinase-like APH PF01636.18 EPE28013.1 - 0.0031 17.2 0.0 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family PDT PF00800.13 EPE28014.1 - 1.6e-63 213.5 0.0 2.9e-61 206.1 0.0 2.1 2 0 0 2 2 2 2 Prephenate dehydratase ACT PF01842.20 EPE28014.1 - 0.00097 18.5 0.0 0.0025 17.2 0.0 1.7 1 0 0 1 1 1 1 ACT domain MaoC_dehydratas PF01575.14 EPE28015.1 - 8.7e-05 21.8 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain PH PF00169.24 EPE28016.1 - 0.078 13.1 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 PH domain FolB PF02152.13 EPE28017.1 - 1.8e-24 86.0 0.0 6.2e-19 68.2 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase Minor_capsid_1 PF10665.4 EPE28017.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Minor capsid protein FYVE PF01363.16 EPE28018.1 - 5.7e-21 74.1 2.1 5.7e-21 74.1 1.5 2.5 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.11 EPE28018.1 - 0.0061 16.4 1.1 0.0061 16.4 0.7 2.4 2 0 0 2 2 2 1 FYVE-type zinc finger DUF1501 PF07394.7 EPE28018.1 - 0.13 11.1 1.0 0.21 10.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) zf-DHHC PF01529.15 EPE28018.1 - 0.29 10.5 4.0 0.4 10.0 0.6 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase ATP_Ca_trans_C PF12424.3 EPE28018.1 - 1.8 8.9 5.4 4.1 7.8 0.0 3.5 3 0 0 3 3 3 0 Plasma membrane calcium transporter ATPase C terminal UDPGP PF01704.13 EPE28019.1 - 2.3e-182 606.2 0.4 2.6e-182 606.0 0.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 EPE28019.1 - 0.017 13.7 2.3 0.048 12.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) HeLo PF14479.1 EPE28020.1 - 5.8e-23 81.7 0.0 1.2e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Ank_2 PF12796.2 EPE28021.1 - 3.6e-33 113.7 0.0 2.3e-12 47.1 0.0 6.0 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPE28021.1 - 4.4e-28 95.6 10.0 1.2e-06 28.0 0.1 8.9 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 EPE28021.1 - 4e-27 93.6 4.3 7e-06 26.1 0.0 7.9 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE28021.1 - 1.1e-24 83.9 6.4 0.0013 18.7 0.1 9.1 9 0 0 9 9 9 6 Ankyrin repeat Pkinase PF00069.20 EPE28021.1 - 2.7e-21 75.9 0.0 4.5e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.1 EPE28021.1 - 4.2e-19 68.5 2.0 0.00011 22.5 0.0 7.0 5 2 4 9 9 9 5 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 EPE28021.1 - 6.5e-16 58.1 0.0 1.2e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPE28021.1 - 0.027 14.2 0.3 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Herpes_US9 PF06072.6 EPE28022.1 - 0.017 14.9 1.5 0.026 14.3 1.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 ETRAMP PF09716.5 EPE28022.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3605 PF12239.3 EPE28023.1 - 9.5e-57 191.2 1.8 1.1e-56 191.0 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Hist_deacetyl PF00850.14 EPE28024.1 - 4.4e-80 269.2 0.1 6e-80 268.8 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.2 EPE28025.1 - 1.4e-21 76.7 3.3 1.9e-21 76.2 2.3 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EPE28025.1 - 3.9e-08 32.8 7.8 6.7e-08 32.1 5.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-CCCH PF00642.19 EPE28026.1 - 1.1e-08 34.4 16.6 4e-07 29.5 1.5 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EPE28026.1 - 1.4e-05 24.7 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE28026.1 - 0.00033 20.2 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE28026.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cys_Met_Meta_PP PF01053.15 EPE28027.1 - 6e-56 189.3 0.0 3e-55 187.0 0.0 2.1 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EPE28027.1 - 0.0067 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V C2 PF00168.25 EPE28028.1 - 3.6e-65 215.7 2.1 3.1e-19 68.6 0.0 5.5 5 0 0 5 5 5 5 C2 domain B56 PF01603.15 EPE28028.1 - 0.23 10.0 0.1 0.37 9.3 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) TRP PF06011.7 EPE28031.1 - 2e-91 306.7 19.4 2.7e-89 299.7 13.5 2.3 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPE28031.1 - 5.6e-26 91.2 0.2 9.1e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 ML-like domain DUF4271 PF14093.1 EPE28031.1 - 0.09 12.4 13.9 0.048 13.3 7.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) Strabismus PF06638.6 EPE28031.1 - 2.3 6.4 4.5 4.7 5.4 3.1 1.4 1 0 0 1 1 1 0 Strabismus protein Herpes_US9 PF06072.6 EPE28031.1 - 7.9 6.3 6.3 0.94 9.3 0.1 2.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Oxysterol_BP PF01237.13 EPE28032.1 - 1.3e-63 214.6 0.0 2e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein MFS_1 PF07690.11 EPE28033.1 - 1.7e-13 50.0 22.8 1.7e-13 50.0 15.8 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily DUF3382 PF11862.3 EPE28033.1 - 0.036 13.9 1.4 0.28 11.1 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) DUF4231 PF14015.1 EPE28033.1 - 0.31 11.0 1.7 11 6.0 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Cu-oxidase_2 PF07731.9 EPE28034.1 - 2e-41 140.7 8.1 2.2e-39 134.1 0.5 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EPE28034.1 - 5.7e-39 132.4 3.0 5.7e-39 132.4 2.1 3.4 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 EPE28034.1 - 7.6e-31 107.1 0.1 3.7e-29 101.6 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Zn_clus PF00172.13 EPE28035.1 - 1.2e-05 25.1 11.2 1.9e-05 24.4 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE28035.1 - 0.00018 20.5 0.0 0.00035 19.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MerR-DNA-bind PF09278.6 EPE28035.1 - 0.086 13.2 0.6 0.19 12.1 0.4 1.5 1 0 0 1 1 1 0 MerR, DNA binding NAD_binding_10 PF13460.1 EPE28036.1 - 1.3e-11 44.8 0.0 1.8e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE28036.1 - 4.5e-05 22.9 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE28036.1 - 0.00013 20.7 0.0 0.00019 20.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EPE28036.1 - 0.00039 20.3 0.0 0.0015 18.4 0.0 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EPE28036.1 - 0.00087 18.2 0.1 0.0053 15.7 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EPE28036.1 - 0.021 14.0 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Semialdhyde_dh PF01118.19 EPE28036.1 - 0.039 14.2 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EPE28036.1 - 0.061 12.2 0.0 0.13 11.1 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FMN_dh PF01070.13 EPE28038.1 - 1.2e-101 340.1 0.0 1.6e-101 339.7 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EPE28038.1 - 4.3e-19 68.0 0.0 1.2e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EPE28038.1 - 4.9e-07 28.9 0.1 7.5e-07 28.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EPE28038.1 - 5.3e-06 25.5 0.0 0.00044 19.2 0.0 2.4 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EPE28038.1 - 0.022 14.0 0.0 0.049 12.8 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.16 EPE28038.1 - 0.048 12.6 0.0 0.096 11.6 0.0 1.4 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.10 EPE28038.1 - 0.054 12.6 0.2 0.09 11.9 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ATP11 PF06644.6 EPE28038.1 - 0.18 11.2 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein Ribul_P_3_epim PF00834.14 EPE28038.1 - 0.21 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Na_Ca_ex PF01699.19 EPE28039.1 - 7.9e-48 161.6 41.3 1.2e-25 89.7 4.3 3.7 4 0 0 4 4 4 2 Sodium/calcium exchanger protein MAPEG PF01124.13 EPE28039.1 - 0.0039 16.7 1.9 0.0039 16.7 1.3 3.2 4 0 0 4 4 4 1 MAPEG family Pex14_N PF04695.8 EPE28039.1 - 0.024 14.6 0.1 0.1 12.6 0.1 2.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Vpu PF00558.14 EPE28039.1 - 0.065 12.8 0.0 0.28 10.7 0.0 2.1 1 0 0 1 1 1 0 Vpu protein Cnd2 PF05786.9 EPE28040.1 - 1.3e-65 222.3 1.7 1.6e-65 221.9 1.2 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Gag_p15 PF08723.5 EPE28040.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Gag protein p15 Cnd2 PF05786.9 EPE28041.1 - 1e-149 500.3 0.1 1.2e-149 500.0 0.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Mid2 PF04478.7 EPE28043.1 - 0.00098 18.5 0.3 0.0019 17.5 0.2 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.1 EPE28043.1 - 0.0042 16.7 0.4 0.011 15.4 0.3 1.7 1 0 0 1 1 1 1 TMEM154 protein family VSP PF03302.8 EPE28043.1 - 0.0061 15.2 1.4 0.0098 14.5 1.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein IncA PF04156.9 EPE28043.1 - 0.018 14.6 0.1 0.036 13.6 0.1 1.4 1 0 0 1 1 1 0 IncA protein Herpes_gE PF02480.11 EPE28043.1 - 0.018 13.3 0.1 0.029 12.6 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 EPE28043.1 - 0.057 12.7 1.2 0.12 11.6 0.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.1 EPE28043.1 - 0.068 13.3 0.0 0.068 13.3 0.0 2.6 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EPE28043.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PH PF00169.24 EPE28044.1 - 2e-06 27.9 0.5 3.5e-05 23.9 0.0 2.8 4 0 0 4 4 4 1 PH domain PH_9 PF15410.1 EPE28044.1 - 0.0075 16.4 2.4 0.014 15.5 0.0 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain PP2C_2 PF13672.1 EPE28045.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EPE28045.1 - 0.00032 20.4 0.0 0.0016 18.1 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EPE28045.1 - 0.0025 17.2 0.0 0.079 12.3 0.0 2.2 1 1 1 2 2 2 1 Protein phosphatase 2C COesterase PF00135.23 EPE28046.1 - 9e-76 255.6 0.7 1.1e-75 255.3 0.5 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE28046.1 - 9.6e-05 22.0 0.2 0.00042 19.9 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE28046.1 - 0.00038 20.2 0.1 0.00074 19.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE28046.1 - 0.0017 18.3 0.2 0.0032 17.3 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EPE28046.1 - 0.024 13.5 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Jag_N PF14804.1 EPE28048.1 - 0.15 12.1 0.7 0.31 11.0 0.5 1.5 1 0 0 1 1 1 0 Jag N-terminus Spherulin4 PF12138.3 EPE28049.1 - 1.6e-51 175.2 0.1 1.8e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Pkinase PF00069.20 EPE28050.1 - 1.5e-68 230.8 0.0 2e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE28050.1 - 2.2e-41 141.6 0.0 3e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE28050.1 - 8.6e-10 38.0 0.1 1.4e-08 34.0 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 EPE28050.1 - 9.1e-05 21.6 0.2 0.00015 20.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPE28050.1 - 0.065 12.5 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EPE28050.1 - 0.081 12.6 0.4 0.29 10.8 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cutinase PF01083.17 EPE28051.1 - 3.2e-50 170.3 0.1 3.8e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EPE28051.1 - 0.002 17.5 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EPE28051.1 - 0.032 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 EPE28051.1 - 0.033 13.9 0.1 0.04 13.6 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE28051.1 - 0.08 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2974 PF11187.3 EPE28051.1 - 0.13 11.6 0.2 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Omega-toxin PF06357.6 EPE28052.1 - 0.0065 16.0 9.9 3.2 7.4 0.1 4.1 4 0 0 4 4 4 2 Omega-atracotoxin Viral_cys_rich PF08008.7 EPE28052.1 - 0.011 15.2 7.3 5.8 6.5 0.0 3.9 4 0 0 4 4 4 0 Viral cysteine rich Toxin_30 PF08117.6 EPE28052.1 - 4.4 7.4 5.3 58 3.8 0.0 3.6 4 0 0 4 4 4 0 Ptu family Trypan_PARP PF05887.6 EPE28052.1 - 6.1 6.6 13.6 2.6 7.8 3.5 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Iso_dh PF00180.15 EPE28053.1 - 3.2e-84 282.8 0.0 4.1e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.3 EPE28055.1 - 3.1e-17 62.8 9.2 4.9e-17 62.1 6.4 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EPE28055.1 - 7.1e-11 42.4 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE28055.1 - 1.5e-07 31.7 0.0 3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE28055.1 - 6.9e-05 22.4 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPE28055.1 - 0.00035 20.1 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EPE28055.1 - 0.00043 20.6 0.0 0.0013 19.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE28055.1 - 0.0006 19.5 0.0 0.00091 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE28055.1 - 0.0027 18.2 0.0 0.0055 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE28055.1 - 0.0038 17.2 0.0 0.0078 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPE28055.1 - 0.011 14.8 0.0 0.51 9.3 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase DUF3724 PF12521.3 EPE28055.1 - 0.069 12.8 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) Cor1 PF04803.7 EPE28056.1 - 0.12 12.0 3.9 0.25 11.0 1.3 2.0 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region Hrs_helical PF12210.3 EPE28056.1 - 0.24 11.6 3.8 0.39 11.0 0.7 2.4 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Syntaxin PF00804.20 EPE28056.1 - 0.54 10.4 6.5 0.41 10.8 3.3 1.7 1 1 1 2 2 2 0 Syntaxin YgaB PF14182.1 EPE28056.1 - 0.88 9.8 5.4 1.2 9.4 1.2 2.2 1 1 1 2 2 2 0 YgaB-like protein G-patch PF01585.18 EPE28057.1 - 8.2e-08 31.9 0.0 8.1e-07 28.7 0.0 2.7 1 1 0 1 1 1 1 G-patch domain DUF936 PF06075.7 EPE28057.1 - 1.3 7.8 29.4 1.6 7.5 20.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DinI PF06183.8 EPE28060.1 - 0.066 13.2 1.3 0.13 12.3 0.9 1.5 1 0 0 1 1 1 0 DinI-like family Imm10 PF15562.1 EPE28061.1 - 0.79 9.5 7.2 0.51 10.1 1.1 2.8 3 0 0 3 3 3 0 Immunity protein 10 CM2 PF03021.9 EPE28064.1 - 0.038 13.5 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Influenza C virus M2 protein Alpha_GJ PF03229.8 EPE28064.1 - 0.065 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Rax2 PF12768.2 EPE28065.1 - 0.019 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Fungal_trans_2 PF11951.3 EPE28066.1 - 4.4e-54 183.5 0.4 7.1e-54 182.8 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_isomerase PF00160.16 EPE28066.1 - 5.2e-50 169.6 0.1 9.9e-50 168.7 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EPE28066.1 - 2.2e-13 49.4 1.1 9.7e-06 25.2 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Zn_clus PF00172.13 EPE28066.1 - 3.5e-08 33.2 7.5 7.2e-08 32.2 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Far-17a_AIG1 PF04750.9 EPE28067.1 - 5.7e-60 201.9 12.4 6.5e-60 201.7 8.6 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein ATP1G1_PLM_MAT8 PF02038.11 EPE28067.1 - 0.07 12.1 0.2 0.15 11.0 0.1 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family HhH-GPD PF00730.20 EPE28068.1 - 3.3e-06 27.3 0.1 2.1e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Cytochrom_C1 PF02167.10 EPE28069.1 - 1.7e-82 276.3 0.0 2.1e-82 276.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EPE28069.1 - 0.0046 17.0 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EPE28069.1 - 0.15 12.9 0.9 0.35 11.7 0.1 2.2 2 1 0 2 2 2 0 Cytochrome c DAHP_synth_1 PF00793.15 EPE28070.1 - 2.3e-98 328.2 0.0 2.9e-98 327.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family NAD_Gly3P_dh_N PF01210.18 EPE28071.1 - 1.1e-45 155.1 0.1 5.1e-45 153.0 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EPE28071.1 - 5.9e-41 139.6 0.3 1e-40 138.8 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus hDGE_amylase PF14701.1 EPE28072.1 - 7.2e-180 598.3 0.0 9.2e-180 598.0 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EPE28072.1 - 7.9e-111 370.3 0.1 1.8e-110 369.2 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EPE28072.1 - 2.2e-89 299.0 0.0 3.5e-89 298.4 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EPE28072.1 - 5.5e-28 96.6 0.1 4e-27 93.8 0.0 2.5 3 0 0 3 3 3 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EPE28072.1 - 1.6e-06 27.7 0.1 0.00084 18.8 0.1 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain YqfQ PF14181.1 EPE28074.1 - 0.015 15.3 1.3 0.019 15.0 0.9 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF788 PF05620.6 EPE28074.1 - 0.016 15.0 0.7 0.041 13.7 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF788) DUF2828 PF11443.3 EPE28074.1 - 0.027 12.6 0.7 0.033 12.4 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RNA_pol_Rpc4 PF05132.9 EPE28075.1 - 0.22 11.4 2.5 1 9.3 1.8 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Tom37_C PF11801.3 EPE28075.1 - 1.5 8.7 4.3 0.62 9.9 1.4 1.4 2 0 0 2 2 2 0 Tom37 C-terminal domain PDR_assoc PF08370.6 EPE28076.1 - 1.2 8.7 3.9 9 5.8 0.2 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated MCM PF00493.18 EPE28077.1 - 7.9e-133 442.3 0.0 1.1e-132 441.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPE28077.1 - 3.2e-27 95.4 0.2 9.4e-27 93.9 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPE28077.1 - 1.8e-07 30.5 0.0 1.7e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPE28077.1 - 3.6e-06 26.7 0.0 1.4e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) phiKZ_IP PF12699.2 EPE28077.1 - 0.035 13.0 0.9 0.065 12.1 0.6 1.3 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Mg_chelatase_2 PF13335.1 EPE28077.1 - 0.039 14.3 0.2 0.15 12.4 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EPE28077.1 - 0.085 12.4 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EPE28078.1 - 2.5e-55 186.2 0.0 1.7e-43 147.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EPE28078.1 - 7.9e-28 96.3 1.5 2.3e-27 94.8 0.2 2.3 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EPE28078.1 - 1.1e-12 48.3 2.3 2.4e-07 30.9 0.0 3.6 2 1 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EPE28078.1 - 1.7e-06 28.8 0.0 0.13 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EPE28078.1 - 1.8e-06 27.6 0.3 0.045 13.4 0.0 3.7 3 1 0 3 3 3 2 NACHT domain AAA_5 PF07728.9 EPE28078.1 - 2.1e-06 27.5 0.1 0.021 14.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPE28078.1 - 2.4e-06 27.5 0.0 0.05 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EPE28078.1 - 3.9e-06 26.8 0.0 0.046 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPE28078.1 - 4.5e-06 26.9 0.5 0.0028 17.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPE28078.1 - 1.4e-05 24.2 0.1 0.0076 15.3 0.0 2.8 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 EPE28078.1 - 1.5e-05 25.1 0.0 0.0036 17.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 EPE28078.1 - 1.7e-05 24.9 0.4 0.42 10.7 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPE28078.1 - 2e-05 24.2 0.2 0.082 12.6 0.0 3.6 3 1 0 3 3 3 1 Part of AAA domain AAA_33 PF13671.1 EPE28078.1 - 2.6e-05 24.1 0.1 0.22 11.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EPE28078.1 - 5e-05 22.5 0.0 0.32 10.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EPE28078.1 - 0.00027 20.4 2.6 0.7 9.2 0.1 3.8 2 2 1 4 4 4 1 AAA domain IstB_IS21 PF01695.12 EPE28078.1 - 0.00055 19.4 0.3 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EPE28078.1 - 0.00063 18.9 0.8 0.13 11.4 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI KTI12 PF08433.5 EPE28078.1 - 0.00069 18.8 0.0 0.0086 15.3 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 TIP49 PF06068.8 EPE28078.1 - 0.001 17.8 0.0 0.62 8.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Sigma54_activat PF00158.21 EPE28078.1 - 0.0014 18.1 0.0 0.098 12.1 0.0 2.6 3 0 0 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EPE28078.1 - 0.0025 17.9 0.0 4 7.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.8 EPE28078.1 - 0.0026 16.7 0.0 0.068 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EPE28078.1 - 0.005 17.1 0.0 3.1 8.1 0.0 2.9 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 EPE28078.1 - 0.0065 16.4 0.1 5.3 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 EPE28078.1 - 0.011 15.5 0.0 4.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin2 PF13189.1 EPE28078.1 - 0.015 15.1 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_29 PF13555.1 EPE28078.1 - 0.022 14.3 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain APS_kinase PF01583.15 EPE28078.1 - 0.039 13.6 0.4 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase Viral_helicase1 PF01443.13 EPE28078.1 - 0.061 12.8 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EPE28078.1 - 0.073 11.9 0.2 5.2 5.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.9 EPE28078.1 - 0.078 11.9 0.1 0.62 8.9 0.0 2.3 2 1 1 3 3 2 0 KAP family P-loop domain UPF0079 PF02367.12 EPE28078.1 - 0.082 12.5 0.1 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SnoaL_4 PF13577.1 EPE28079.1 - 9.3e-18 64.3 0.0 1.1e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain PNMA PF14893.1 EPE28079.1 - 0.031 13.2 0.1 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 PNMA Peptidase_C48 PF02902.14 EPE28081.1 - 6e-16 58.7 0.0 2.1e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Chromo PF00385.19 EPE28082.1 - 0.00011 21.8 1.4 0.00025 20.6 1.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pam17 PF08566.5 EPE28083.1 - 6e-66 221.4 0.0 7.7e-66 221.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Myosin_HC-like PF07058.6 EPE28083.1 - 0.079 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Myosin II heavy chain-like ThiF PF00899.16 EPE28084.1 - 1.1e-41 141.8 0.0 1.8e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EPE28084.1 - 8.2e-23 79.8 0.1 1.3e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EPE28084.1 - 8.8e-13 48.6 0.0 2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EPE28084.1 - 0.031 14.3 1.1 0.24 11.5 0.1 2.7 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EPE28084.1 - 0.16 12.2 0.0 0.66 10.2 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding FlxA PF14282.1 EPE28084.1 - 0.18 11.7 3.2 0.18 11.7 1.1 1.8 2 0 0 2 2 2 0 FlxA-like protein SLX9 PF15341.1 EPE28085.1 - 1.1e-27 96.9 0.9 1.1e-27 96.9 0.7 1.5 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 AP_endonuc_2 PF01261.19 EPE28086.1 - 3.7e-34 117.8 0.0 4.5e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AKAP7_NLS PF10469.4 EPE28087.1 - 0.11 12.1 0.4 0.93 9.1 0.0 2.1 2 0 0 2 2 2 0 AKAP7 2'5' RNA ligase-like domain zf-CCHC_6 PF15288.1 EPE28088.1 - 0.11 12.1 0.4 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle ADH_N PF08240.7 EPE28089.1 - 3.1e-16 59.0 0.2 7.9e-16 57.7 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE28089.1 - 8.3e-08 31.8 0.0 8.3e-07 28.6 0.0 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EPE28089.1 - 0.0026 16.2 0.0 0.004 15.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EPE28089.1 - 0.086 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HET PF06985.6 EPE28090.1 - 1.9e-29 102.6 0.2 3e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RabGAP-TBC PF00566.13 EPE28094.1 - 0.092 12.2 0.3 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 Rab-GTPase-TBC domain ORC6 PF05460.8 EPE28098.1 - 0.4 9.7 8.7 0.49 9.4 6.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pyr_redox_3 PF13738.1 EPE28099.1 - 1.1e-18 68.0 0.0 2.7e-18 66.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE28099.1 - 4.9e-14 51.4 0.0 2.5e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EPE28099.1 - 7.2e-13 48.8 0.0 8e-12 45.4 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE28099.1 - 2e-10 40.5 0.3 4.2e-08 33.0 0.0 3.5 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EPE28099.1 - 2.8e-07 29.8 0.3 3.3e-06 26.2 0.1 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPE28099.1 - 3.9e-07 29.9 0.6 5.7e-06 26.1 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EPE28099.1 - 3.9e-06 26.0 0.1 0.072 11.9 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EPE28099.1 - 6.3e-05 22.2 0.0 0.00038 19.6 0.0 2.2 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EPE28099.1 - 0.00026 21.3 2.5 0.2 12.0 0.0 3.2 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE28099.1 - 0.00039 18.9 0.0 0.066 11.6 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 EPE28099.1 - 0.00099 18.2 1.0 0.0015 17.6 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EPE28099.1 - 0.002 17.2 0.0 0.016 14.2 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain Trp_halogenase PF04820.9 EPE28099.1 - 0.054 12.1 0.0 0.1 11.1 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase YtkA PF13115.1 EPE28099.1 - 0.22 11.9 2.4 19 5.6 0.0 2.7 2 0 0 2 2 2 0 YtkA-like NACHT PF05729.7 EPE28101.1 - 6.7e-07 29.1 0.1 3.8e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 NACHT domain DUF676 PF05057.9 EPE28101.1 - 8.3e-06 25.2 0.1 2.7e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EPE28101.1 - 0.0022 17.6 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPE28101.1 - 0.0031 17.2 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE28101.1 - 0.0032 17.3 0.0 0.0094 15.8 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family RNA_helicase PF00910.17 EPE28101.1 - 0.0046 17.0 0.1 0.046 13.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 EPE28101.1 - 0.0077 16.3 0.1 0.054 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPE28101.1 - 0.017 15.4 0.0 0.053 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPE28101.1 - 0.037 14.8 0.0 0.26 12.1 0.0 2.5 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 EPE28101.1 - 0.04 13.8 0.1 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EPE28101.1 - 0.043 14.1 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 EPE28101.1 - 0.045 13.2 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Septin PF00735.13 EPE28101.1 - 0.046 12.7 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_33 PF13671.1 EPE28101.1 - 0.052 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EPE28101.1 - 0.072 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EPE28101.1 - 0.097 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EPE28101.1 - 0.21 11.1 0.0 0.61 9.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EPE28102.1 - 4.2e-35 121.1 25.7 4.2e-35 121.1 17.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Trep_Strep PF09605.5 EPE28103.1 - 0.034 13.8 1.1 0.071 12.7 0.8 1.5 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) TauE PF01925.14 EPE28103.1 - 0.14 11.5 8.4 0.011 15.2 2.6 1.6 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE CFEM PF05730.6 EPE28103.1 - 0.27 11.0 10.7 0.85 9.4 7.4 1.8 1 1 0 1 1 1 0 CFEM domain eIF2A PF08662.6 EPE28107.1 - 8.8e-38 129.9 6.9 1.1e-36 126.4 0.3 4.0 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 EPE28107.1 - 8e-05 22.5 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE28107.1 - 8.5e-05 22.1 0.0 0.00021 20.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EPE28107.1 - 0.00029 20.5 0.0 0.11 12.4 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat RRM_5 PF13893.1 EPE28107.1 - 0.0018 18.0 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.19 EPE28108.1 - 1.2e-133 446.2 10.0 1.4e-133 446.0 7.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribonuc_2-5A PF06479.7 EPE28109.1 - 2.8e-44 150.0 0.2 7.2e-44 148.7 0.1 1.8 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EPE28109.1 - 2e-43 148.4 0.0 3.1e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE28109.1 - 4.6e-22 78.3 0.0 2.7e-20 72.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Ada_Zn_binding PF02805.11 EPE28110.1 - 1.7e-26 91.5 3.1 3.3e-26 90.6 2.1 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EPE28110.1 - 9.3e-09 34.8 0.0 2.1e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EPE28110.1 - 0.00094 19.2 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EPE28110.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Flavin_Reduct PF01613.13 EPE28111.1 - 5.6e-10 39.2 0.0 7.8e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 EPE28111.1 - 0.00044 19.8 0.0 0.0006 19.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF447) Abhydrolase_6 PF12697.2 EPE28112.1 - 7.3e-13 48.9 0.0 1.1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE28112.1 - 7.7e-07 28.8 0.0 9.1e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold SWIB PF02201.13 EPE28113.1 - 5.8e-26 89.9 0.1 9.6e-26 89.2 0.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EPE28113.1 - 9.1e-11 41.3 0.4 1.8e-10 40.4 0.3 1.5 1 0 0 1 1 1 1 DEK C terminal domain zf-C3HC4_3 PF13920.1 EPE28114.1 - 0.00015 21.3 9.8 0.00015 21.3 6.8 2.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Epimerase PF01370.16 EPE28115.1 - 3e-09 36.6 0.1 0.00022 20.7 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE28115.1 - 6.1e-07 29.6 0.4 1.7e-06 28.2 0.2 1.7 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EPE28115.1 - 9e-07 28.3 0.1 1.4e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EPE28115.1 - 1.4e-05 25.4 0.1 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EPE28115.1 - 0.0076 15.1 0.1 0.017 14.0 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EPE28115.1 - 0.035 12.9 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.15 EPE28115.1 - 0.062 13.2 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NACHT PF05729.7 EPE28116.1 - 1.1e-08 34.8 0.0 2.8e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EPE28116.1 - 0.0066 16.5 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EPE28116.1 - 0.018 14.4 0.3 0.042 13.2 0.2 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 EPE28116.1 - 0.046 14.0 0.1 0.046 14.0 0.1 2.7 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.1 EPE28116.1 - 0.092 13.0 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPE28116.1 - 0.095 12.2 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EPE28116.1 - 0.099 12.9 1.1 0.22 11.7 0.1 2.1 2 1 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 EPE28116.1 - 0.23 12.2 2.5 1.2 9.9 0.8 3.1 2 1 0 2 2 2 0 AAA domain zf-MYND PF01753.13 EPE28118.1 - 1.2e-07 31.4 14.6 4e-07 29.8 10.2 1.9 1 1 0 1 1 1 1 MYND finger DUF3840 PF12944.2 EPE28120.1 - 0.097 12.5 0.2 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3840) Microvir_J PF04726.8 EPE28122.1 - 0.12 12.3 2.0 0.24 11.3 1.4 1.5 1 0 0 1 1 1 0 Microvirus J protein Poxvirus_B22R_N PF13169.1 EPE28125.1 - 0.034 14.3 0.1 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal RhoGAP PF00620.22 EPE28127.1 - 3.4e-28 98.1 0.0 6e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain TMEM171 PF15471.1 EPE28127.1 - 0.32 9.7 2.7 0.99 8.1 1.9 1.8 1 0 0 1 1 1 0 Transmembrane protein family 171 RRS1 PF04939.7 EPE28128.1 - 1.4e-59 200.2 2.8 1.6e-59 200.0 1.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.4 EPE28129.1 - 2.6e-94 315.6 0.0 3.2e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 DUF2791 PF10923.3 EPE28129.1 - 0.026 13.1 0.2 0.13 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) 6PF2K PF01591.13 EPE28131.1 - 0.012 14.6 3.9 0.18 10.8 0.0 2.6 2 1 0 2 2 2 0 6-phosphofructo-2-kinase DUF3161 PF11362.3 EPE28131.1 - 0.04 13.8 0.4 0.21 11.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3161) SBF PF01758.11 EPE28131.1 - 0.19 11.0 0.1 0.32 10.3 0.1 1.2 1 0 0 1 1 1 0 Sodium Bile acid symporter family Phage_int_SAM_2 PF12834.2 EPE28131.1 - 1.5 9.2 7.0 0.18 12.2 1.2 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal DUF2203 PF09969.4 EPE28131.1 - 3.4 7.9 5.7 4 7.6 1.8 2.7 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) DnaJ PF00226.26 EPE28133.1 - 1.5e-23 82.2 0.1 3.5e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Trm112p PF03966.11 EPE28133.1 - 0.051 13.9 1.7 0.19 12.0 0.0 2.8 3 1 0 3 3 3 0 Trm112p-like protein FYVE PF01363.16 EPE28133.1 - 0.23 11.3 4.7 0.47 10.3 3.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger C1_1 PF00130.17 EPE28133.1 - 0.99 9.1 5.6 2 8.2 3.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MBOAT_2 PF13813.1 EPE28134.1 - 3.6e-16 58.9 5.3 1e-15 57.5 3.7 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family GD_AH_C PF04295.8 EPE28134.1 - 0.12 10.9 0.2 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus bZIP_1 PF00170.16 EPE28135.1 - 0.00095 19.0 6.4 0.0017 18.2 4.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor Mif2_N PF15624.1 EPE28135.1 - 0.35 11.4 5.7 0.53 10.8 3.9 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal bZIP_2 PF07716.10 EPE28135.1 - 0.46 10.3 5.8 0.73 9.7 4.0 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Fungal_trans_2 PF11951.3 EPE28136.1 - 3.1e-16 58.9 1.3 5.9e-16 58.0 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_U5 PF05999.6 EPE28136.1 - 0.039 12.5 0.1 0.086 11.4 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus U5-like family FAD_binding_4 PF01565.18 EPE28137.1 - 1.9e-22 79.2 1.9 1.9e-22 79.2 1.3 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPE28137.1 - 1.3e-12 47.3 0.1 2.9e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like MutS_V PF00488.16 EPE28138.1 - 6.8e-86 287.4 0.1 1.2e-85 286.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPE28138.1 - 9.9e-39 133.2 1.0 1.9e-38 132.2 0.7 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EPE28138.1 - 2.8e-27 94.9 0.0 5.9e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EPE28138.1 - 1.6e-06 28.1 0.0 5.3e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EPE28138.1 - 3.6e-06 27.0 0.0 1.4e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 MutS family domain IV zf-C2H2_4 PF13894.1 EPE28139.1 - 0.15 12.4 0.9 0.4 11.1 0.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE28139.1 - 0.32 11.4 2.0 0.86 10.0 1.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Prenyltrans PF00432.16 EPE28140.1 - 7e-58 191.8 11.0 1.2e-12 47.1 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPE28140.1 - 3.7e-36 123.9 0.0 8.7e-16 58.3 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPE28140.1 - 3.3e-09 36.7 0.0 0.00045 20.2 0.0 2.8 2 1 1 3 3 3 2 Prenyltransferase-like AIG2_2 PF13772.1 EPE28141.1 - 9.5e-07 28.8 0.0 3.2e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 AIG2-like family Amidoligase_2 PF12224.3 EPE28142.1 - 1.2e-31 110.3 0.1 3.5e-30 105.4 0.1 2.1 1 1 0 1 1 1 1 Putative amidoligase enzyme HLH PF00010.21 EPE28146.1 - 2.4e-08 33.5 0.5 5.8e-08 32.3 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_2 PF07716.10 EPE28146.1 - 0.0095 15.7 3.2 0.033 13.9 2.2 1.9 1 0 0 1 1 1 1 Basic region leucine zipper Fzo_mitofusin PF04799.8 EPE28146.1 - 0.037 13.3 2.2 0.067 12.5 1.5 1.4 1 0 0 1 1 1 0 fzo-like conserved region RTBV_P46 PF06216.6 EPE28146.1 - 0.069 11.9 1.2 0.1 11.4 0.8 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein bZIP_1 PF00170.16 EPE28146.1 - 0.52 10.3 7.5 0.4 10.6 3.6 2.0 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 EPE28146.1 - 1.9 8.0 6.0 0.37 10.3 1.1 2.0 2 0 0 2 2 2 0 Septum formation initiator CTF_NFI PF00859.13 EPE28146.1 - 3.2 7.4 15.0 6.9 6.3 5.3 2.2 1 1 1 2 2 2 0 CTF/NF-I family transcription modulation region DUF972 PF06156.8 EPE28146.1 - 3.5 8.0 6.6 2.1 8.7 2.6 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Striatin PF08232.7 EPE28146.1 - 4.7 7.5 10.5 11 6.3 2.2 2.4 2 0 0 2 2 2 0 Striatin family Cu-oxidase_3 PF07732.10 EPE28147.1 - 1.9e-22 79.1 0.2 4.8e-22 77.9 0.1 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPE28147.1 - 1.3e-21 76.5 4.3 7.5e-20 70.8 1.8 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EPE28147.1 - 7.3e-09 35.7 0.0 2.9e-06 27.2 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase peroxidase PF00141.18 EPE28148.1 - 3.7e-27 95.3 0.0 5.8e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EPE28148.1 - 0.002 17.9 0.0 0.0065 16.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) Ribosomal_S28e PF01200.13 EPE28149.1 - 4.6e-33 112.7 2.6 5e-33 112.6 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.13 EPE28150.1 - 3.3e-49 166.6 1.1 1.6e-47 161.1 0.8 2.4 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EPE28150.1 - 2.9e-29 100.8 0.4 5e-29 100.0 0.3 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EPE28150.1 - 0.041 13.4 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 NMT1/THI5 like Cytokin_check_N PF10407.4 EPE28152.1 - 0.0086 15.6 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Lipase_GDSL_2 PF13472.1 EPE28153.1 - 2.2e-12 47.4 0.6 3.9e-12 46.6 0.4 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE28153.1 - 9.8e-11 41.9 3.3 4.6e-10 39.7 2.3 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Brr6_like_C_C PF10104.4 EPE28155.1 - 0.47 9.9 2.4 0.42 10.1 0.4 1.8 2 1 1 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain zf-C2H2_4 PF13894.1 EPE28155.1 - 1.7 9.1 6.4 0.42 11.0 0.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Fungal_trans_2 PF11951.3 EPE28156.1 - 0.00021 20.0 0.1 0.00036 19.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE28156.1 - 0.00082 19.2 4.6 0.0014 18.5 3.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.18 EPE28157.1 - 1.1e-06 28.5 20.4 1.6e-06 27.9 13.9 1.5 1 1 0 1 1 1 1 Membrane-associating domain Tetraspannin PF00335.15 EPE28157.1 - 4.3 6.5 11.4 17 4.6 7.9 1.9 1 1 0 1 1 1 0 Tetraspanin family Glyco_transf_28 PF03033.15 EPE28158.1 - 2e-20 72.9 0.0 6.7e-20 71.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EPE28158.1 - 9.3e-08 31.0 0.0 1.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase FAD_binding_4 PF01565.18 EPE28159.1 - 2.5e-19 69.1 1.2 2.5e-19 69.1 0.8 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPE28159.1 - 3.5e-07 30.0 0.7 7.6e-07 28.9 0.5 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF3733 PF12534.3 EPE28160.1 - 0.028 13.7 1.2 0.062 12.6 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 p450 PF00067.17 EPE28162.1 - 5.6e-37 127.3 0.0 7.2e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3328 PF11807.3 EPE28163.1 - 6.8e-31 107.6 0.0 8.4e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pex2_Pex12 PF04757.9 EPE28164.1 - 3.6e-40 137.8 9.8 4.5e-40 137.4 6.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EPE28164.1 - 1.3e-10 40.9 7.8 2.1e-10 40.2 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE28164.1 - 2.6e-10 40.1 7.6 4.2e-10 39.4 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE28164.1 - 8.9e-10 38.0 5.1 1.4e-09 37.4 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE28164.1 - 1.8e-09 37.1 5.4 3e-09 36.3 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE28164.1 - 6.6e-07 28.9 4.8 1.1e-06 28.2 3.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPE28164.1 - 9.5e-07 28.5 7.6 1.6e-06 27.8 5.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EPE28164.1 - 8.2e-05 22.6 8.6 0.00028 20.9 5.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EPE28164.1 - 0.00018 21.2 2.6 0.00035 20.2 1.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EPE28164.1 - 0.0024 17.5 4.1 0.0058 16.3 2.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EPE28164.1 - 0.015 14.8 5.2 0.032 13.8 3.6 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EPE28164.1 - 0.052 13.0 1.9 0.1 12.1 1.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.16 EPE28164.1 - 2.2 8.2 7.3 6.4 6.7 4.9 1.9 1 1 0 1 1 1 0 IBR domain FYVE PF01363.16 EPE28164.1 - 6.1 6.8 8.0 24 4.8 5.6 2.0 1 1 0 1 1 1 0 FYVE zinc finger EXS PF03124.9 EPE28165.1 - 3.1e-101 338.8 5.1 3.6e-101 338.6 3.5 1.0 1 0 0 1 1 1 1 EXS family ABC_tran PF00005.22 EPE28166.1 - 2.9e-41 140.9 0.0 9.4e-23 81.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPE28166.1 - 8.1e-34 117.2 22.9 2.2e-24 86.3 8.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EPE28166.1 - 9.7e-07 29.0 0.1 1 9.2 0.1 4.3 3 1 1 4 4 4 1 AAA domain AAA_29 PF13555.1 EPE28166.1 - 1e-06 28.1 3.9 0.0039 16.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EPE28166.1 - 1.4e-06 28.5 0.0 0.062 13.4 0.0 3.3 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EPE28166.1 - 3.6e-06 26.3 0.1 3.5 6.7 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EPE28166.1 - 4.3e-06 25.8 0.8 0.032 13.1 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 EPE28166.1 - 8.3e-06 25.0 0.4 0.072 12.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EPE28166.1 - 1.5e-05 24.6 0.3 0.059 12.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 EPE28166.1 - 3e-05 23.5 2.2 0.22 10.8 0.1 3.1 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EPE28166.1 - 4.4e-05 23.3 0.3 0.14 11.9 0.0 2.4 2 0 0 2 2 2 2 Dynamin family Miro PF08477.8 EPE28166.1 - 8.3e-05 23.0 0.3 0.19 12.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EPE28166.1 - 0.00013 21.9 0.1 0.38 10.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 EPE28166.1 - 0.00026 20.6 0.6 0.028 14.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EPE28166.1 - 0.00041 20.3 0.7 0.034 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EPE28166.1 - 0.0012 18.3 4.5 0.35 10.2 0.1 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_33 PF13671.1 EPE28166.1 - 0.0043 16.9 0.0 0.36 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EPE28166.1 - 0.0094 15.6 0.7 0.22 11.1 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_23 PF13476.1 EPE28166.1 - 0.043 14.1 6.4 2.1 8.6 0.6 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EPE28166.1 - 0.068 13.4 3.4 5.3 7.3 0.3 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EPE28166.1 - 0.078 12.6 2.6 2.5 7.7 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EPE28166.1 - 0.16 12.7 6.2 5.7 7.7 0.4 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EPE28166.1 - 0.35 10.5 1.9 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_15 PF13175.1 EPE28166.1 - 0.37 9.7 0.4 0.87 8.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 EPE28166.1 - 0.37 10.3 2.8 16 5.0 0.2 2.8 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 EPE28166.1 - 0.47 10.2 6.3 1.5 8.6 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 EPE28166.1 - 0.65 9.4 2.9 5.9 6.3 0.3 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TrwB_AAD_bind PF10412.4 EPE28166.1 - 1.5 7.4 4.8 8.8 4.8 0.3 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 EPE28166.1 - 1.6 8.1 5.5 1.7 8.0 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Phage_T7_Capsid PF05396.6 EPE28167.1 - 0.054 13.6 0.4 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Phage T7 capsid assembly protein CENP-X PF09415.5 EPE28169.1 - 0.034 13.9 1.8 0.086 12.6 0.1 2.3 3 0 0 3 3 3 0 CENP-S associating Centromere protein X GFA PF04828.9 EPE28171.1 - 2.2e-08 33.9 1.8 2.2e-08 33.9 1.2 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EPE28171.1 - 0.034 13.6 1.0 0.095 12.2 0.7 1.7 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-RING_6 PF14835.1 EPE28171.1 - 0.092 12.5 0.3 0.092 12.5 0.2 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 EPE28171.1 - 1.7 8.3 8.0 16 5.2 5.7 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.8 EPE28172.1 - 0.61 9.9 6.0 0.79 9.5 4.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Amidohydro_1 PF01979.15 EPE28173.1 - 1.4e-34 120.3 0.0 1.8e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EPE28173.1 - 1e-24 88.0 0.0 9.9e-24 84.8 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPE28173.1 - 3.4e-12 46.2 2.9 1.9e-10 40.5 0.1 2.4 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EPE28173.1 - 1.2e-10 41.0 0.1 5e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Fungal_trans PF04082.13 EPE28174.1 - 2e-07 30.1 3.4 2.3e-06 26.6 2.3 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE28174.1 - 1.5e-05 24.7 7.4 4.1e-05 23.3 5.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EPE28174.1 - 0.12 12.5 8.6 0.33 11.1 6.0 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region YlbD_coat PF14071.1 EPE28174.1 - 0.24 11.4 1.0 0.46 10.5 0.7 1.4 1 0 0 1 1 1 0 Putative coat protein Fungal_trans PF04082.13 EPE28175.1 - 1.9e-27 95.8 0.2 3.4e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE28175.1 - 6.7e-06 25.9 9.4 6.7e-06 25.9 6.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE28176.1 - 4e-32 111.2 24.6 4e-32 111.2 17.0 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE28176.1 - 1.5e-13 50.1 7.2 1.5e-13 50.1 5.0 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EPE28176.1 - 0.00011 20.5 1.1 0.00016 20.0 0.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Leader_Erm PF08253.6 EPE28176.1 - 0.068 12.6 1.1 0.14 11.6 0.8 1.5 1 0 0 1 1 1 0 Erm Leader peptide Grp1_Fun34_YaaH PF01184.14 EPE28177.1 - 4e-85 284.4 22.0 5e-85 284.0 15.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Velvet PF11754.3 EPE28178.1 - 1.1e-72 243.9 0.0 1.6e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Fer2_3 PF13085.1 EPE28179.1 - 5.4e-31 106.6 0.0 8.9e-31 105.9 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EPE28179.1 - 1.1e-09 38.4 7.3 1.1e-09 38.4 5.1 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EPE28179.1 - 1.7e-08 34.3 5.9 1.7e-08 34.3 4.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EPE28179.1 - 0.00017 21.9 8.2 0.00052 20.3 1.6 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EPE28179.1 - 0.00024 21.2 5.0 0.013 15.7 0.9 3.0 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EPE28179.1 - 0.0045 16.7 6.7 0.0045 16.7 4.6 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EPE28179.1 - 0.0092 15.7 0.5 0.0092 15.7 0.3 2.5 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 EPE28179.1 - 0.029 14.7 8.8 0.029 14.7 6.1 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EPE28179.1 - 3.9 8.1 7.7 0.62 10.6 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain Abhydrolase_5 PF12695.2 EPE28180.1 - 3.8e-23 81.8 0.0 5.3e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE28180.1 - 9.8e-16 58.3 0.0 2.4e-14 53.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE28180.1 - 3.2e-07 30.0 0.0 0.0044 16.4 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.7 EPE28180.1 - 2.4e-05 22.9 0.3 0.81 8.1 0.0 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 EPE28180.1 - 5.8e-05 22.6 0.0 0.00023 20.7 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EPE28180.1 - 0.0001 21.9 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EPE28180.1 - 0.00012 21.6 0.0 0.0093 15.5 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE28180.1 - 0.00036 19.8 0.0 0.00084 18.6 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.7 EPE28180.1 - 0.0011 17.8 0.0 0.0015 17.3 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.6 EPE28180.1 - 0.0013 18.5 0.0 0.013 15.2 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EPE28180.1 - 0.004 16.4 0.0 0.082 12.1 0.0 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EPE28180.1 - 0.013 14.9 0.0 1.4 8.2 0.0 2.6 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EPE28180.1 - 0.013 15.3 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 EPE28180.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase zf-LYAR PF08790.6 EPE28181.1 - 5.1e-14 51.6 3.0 5.1e-14 51.6 2.1 1.7 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF1675 PF07897.6 EPE28181.1 - 4.2 7.1 10.4 1.3 8.7 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1675) R3H PF01424.17 EPE28182.1 - 2.7e-13 49.3 0.1 5e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EPE28182.1 - 1.8e-06 27.7 67.3 0.00015 21.6 8.3 12.8 12 1 0 12 12 12 6 NF-X1 type zinc finger Kelch_5 PF13854.1 EPE28183.1 - 2.3e-08 33.8 1.9 9.2e-05 22.3 0.0 4.2 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 EPE28183.1 - 0.00033 20.1 0.8 0.38 10.3 0.0 3.8 3 0 0 3 3 3 1 Kelch motif Mid2 PF04478.7 EPE28183.1 - 0.018 14.4 0.0 0.045 13.1 0.0 1.6 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor VSP PF03302.8 EPE28183.1 - 0.064 11.8 0.1 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein Syndecan PF01034.15 EPE28183.1 - 0.099 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Kelch_2 PF07646.10 EPE28183.1 - 0.85 9.4 5.4 12 5.8 0.0 4.2 4 0 0 4 4 4 0 Kelch motif SKG6 PF08693.5 EPE28183.1 - 3.2 7.1 5.3 0.35 10.2 0.2 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF3602 PF12223.3 EPE28184.1 - 1.7e-15 57.1 12.1 4.8e-13 49.3 2.8 2.6 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Cpl-7 PF08230.6 EPE28184.1 - 0.13 12.0 0.2 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Cpl-7 lysozyme C-terminal domain RhoGEF PF00621.15 EPE28185.1 - 1.6e-29 103.0 0.0 3e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EPE28185.1 - 0.001 18.6 0.8 0.0021 17.5 0.5 1.5 1 0 0 1 1 1 1 BAR domain Telomerase_RBD PF12009.3 EPE28186.1 - 5.6e-42 142.8 3.2 1.5e-41 141.4 2.2 1.8 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EPE28186.1 - 1.4e-17 63.7 0.0 7.9e-17 61.3 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FANCI_S2 PF14676.1 EPE28187.1 - 0.026 14.4 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 2 RabGAP-TBC PF00566.13 EPE28188.1 - 2.6e-32 112.0 0.0 4e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3328 PF11807.3 EPE28189.1 - 4.4e-19 69.0 0.2 6.7e-19 68.4 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3399 PF11879.3 EPE28189.1 - 0.12 12.5 5.1 1.9 8.7 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3399) DUF3328 PF11807.3 EPE28190.1 - 3.5e-54 183.7 0.0 4.4e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EPE28192.1 - 3.2e-35 121.4 25.7 4.5e-35 120.9 17.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EPE28192.1 - 0.00026 20.5 1.2 0.00079 18.9 0.8 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 CoA_trans PF01144.18 EPE28194.1 - 1.5e-100 334.8 6.7 9.9e-61 204.6 1.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EPE28194.1 - 0.04 13.5 0.1 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Chitin_bind_3 PF03067.10 EPE28195.1 - 3.2e-05 24.2 0.0 5.6e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Chitin binding domain MFS_1 PF07690.11 EPE28196.1 - 9.9e-33 113.2 31.3 5.9e-31 107.4 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.7 EPE28196.1 - 0.003 17.0 0.1 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF697) MFS_2 PF13347.1 EPE28196.1 - 0.023 13.0 20.6 0.2 10.0 11.4 3.8 1 1 1 2 2 2 0 MFS/sugar transport protein adh_short PF00106.20 EPE28197.1 - 7.1e-25 87.8 0.4 9.7e-25 87.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE28197.1 - 5.2e-12 46.0 0.3 6.7e-12 45.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE28197.1 - 1.9e-11 43.9 0.4 2.5e-11 43.5 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE28197.1 - 2.8e-05 23.6 0.4 5.8e-05 22.6 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE28197.1 - 0.0074 15.0 0.2 0.023 13.3 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.11 EPE28197.1 - 0.0087 16.5 0.5 0.015 15.8 0.3 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Eno-Rase_NADH_b PF12242.3 EPE28197.1 - 0.017 14.9 0.6 0.037 13.8 0.2 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ldh_1_N PF00056.18 EPE28197.1 - 0.025 14.3 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EPE28197.1 - 0.033 13.1 0.2 0.071 12.0 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.10 EPE28197.1 - 0.036 12.9 0.3 0.049 12.5 0.2 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_synthase PF02540.12 EPE28197.1 - 0.057 12.3 0.2 0.082 11.7 0.2 1.1 1 0 0 1 1 1 0 NAD synthase MFS_1 PF07690.11 EPE28198.1 - 5.5e-33 114.1 45.3 5.5e-33 114.1 31.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE28198.1 - 2.4e-13 49.4 6.5 2.4e-13 49.4 4.5 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter p450 PF00067.17 EPE28199.1 - 1.8e-51 175.1 0.0 2.3e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 EPE28200.1 - 1.3e-24 86.7 0.0 1.6e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_2 PF00891.13 EPE28201.1 - 3.1e-16 59.3 0.0 4.6e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase HTH_24 PF13412.1 EPE28201.1 - 0.068 12.5 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 EPE28201.1 - 0.12 11.9 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain NmrA PF05368.8 EPE28203.1 - 8.7e-32 110.2 0.0 1e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE28203.1 - 3.8e-17 62.8 0.0 5e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding p450 PF00067.17 EPE28204.1 - 3.2e-23 82.0 0.0 8.2e-23 80.6 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Methyltransf_2 PF00891.13 EPE28205.1 - 9.8e-26 90.4 0.0 1.4e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EPE28205.1 - 0.0023 17.6 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain BsuBI_PstI_RE PF06616.6 EPE28205.1 - 0.075 11.8 0.0 0.15 10.8 0.0 1.5 1 1 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus HTH_24 PF13412.1 EPE28205.1 - 0.088 12.2 0.0 0.26 10.7 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF977 PF06163.6 EPE28205.1 - 0.14 11.9 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) Methyltransf_2 PF00891.13 EPE28206.1 - 1.8e-37 128.8 0.1 2.5e-37 128.3 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EPE28206.1 - 0.013 16.0 0.0 0.038 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 EPE28207.1 - 6.8e-60 202.5 0.0 1e-59 202.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EPE28207.1 - 1.4e-26 94.1 0.0 4.6e-25 89.1 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EPE28207.1 - 4.9e-11 42.7 0.0 1.1e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EPE28207.1 - 5.3e-06 26.4 0.2 1.2e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE28207.1 - 0.0027 17.4 0.0 0.0067 16.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family GH3 PF03321.8 EPE28207.1 - 0.015 13.8 0.0 2.6 6.4 0.0 2.3 2 0 0 2 2 2 0 GH3 auxin-responsive promoter PE-PPE PF08237.6 EPE28207.1 - 0.18 11.1 0.0 0.85 8.9 0.0 2.0 2 0 0 2 2 2 0 PE-PPE domain Aminotran_1_2 PF00155.16 EPE28208.1 - 1.9e-44 152.0 0.0 2.4e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPE28208.1 - 0.00049 19.3 0.0 0.00085 18.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase BNR_2 PF13088.1 EPE28209.1 - 5.7e-05 22.5 0.0 0.011 15.0 0.0 2.6 1 1 1 2 2 2 2 BNR repeat-like domain DUF2690 PF10901.3 EPE28209.1 - 0.048 13.6 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2690) BNR PF02012.15 EPE28209.1 - 0.77 9.8 6.4 6 7.1 0.0 4.6 5 0 0 5 5 5 0 BNR/Asp-box repeat 2OG-FeII_Oxy_3 PF13640.1 EPE28210.1 - 2.5e-08 34.3 0.0 4.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EPE28210.1 - 3.2e-07 29.8 0.0 1.5e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 EPE28211.1 - 2.3e-93 312.8 0.0 5.2e-93 311.7 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPE28211.1 - 5.3e-55 186.0 0.0 1.1e-54 184.9 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EPE28211.1 - 3.4e-16 59.4 0.0 5.7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPE28211.1 - 1.1e-11 44.1 0.0 8.7e-11 41.2 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EPE28211.1 - 5e-11 41.8 0.0 9.7e-11 40.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EPE28211.1 - 3.3e-06 27.9 0.0 8.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 EPE28211.1 - 1.7e-05 24.9 0.1 9.6e-05 22.4 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding PP-binding PF00550.20 EPE28211.1 - 0.00013 22.1 0.0 0.00032 20.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EPE28211.1 - 0.0055 15.6 0.0 0.022 13.6 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPE28211.1 - 0.038 13.9 0.6 0.13 12.1 0.4 1.9 1 1 0 1 1 1 0 short chain dehydrogenase tRNA-synt_1b PF00579.20 EPE28212.1 - 2.5e-52 177.8 0.0 3e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HIT PF01230.18 EPE28213.1 - 2.1e-24 85.8 0.0 3e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPE28213.1 - 1.1e-07 32.0 0.1 1.7e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding APH PF01636.18 EPE28215.1 - 5.9e-21 75.2 0.1 8.7e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE28215.1 - 8.6e-14 51.6 0.0 7.4e-13 48.5 0.0 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPE28215.1 - 0.0014 17.7 0.3 0.0022 17.1 0.2 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.9 EPE28215.1 - 0.0021 17.1 0.1 0.0029 16.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH_6_hur PF04655.9 EPE28215.1 - 0.14 11.2 2.7 0.095 11.8 0.2 1.9 2 1 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Transferase PF02458.10 EPE28217.1 - 3e-37 128.1 0.0 3.7e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Transferase family Metallophos_C PF14008.1 EPE28217.1 - 0.029 14.4 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Iron/zinc purple acid phosphatase-like protein C U3_snoRNA_assoc PF08297.6 EPE28219.1 - 0.045 13.9 3.5 0.081 13.1 2.4 1.4 1 0 0 1 1 1 0 U3 snoRNA associated OAD_gamma PF04277.8 EPE28219.1 - 7.2 7.0 5.4 22 5.5 1.7 2.6 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ThuA PF06283.6 EPE28220.1 - 0.016 14.8 0.1 0.022 14.4 0.1 1.1 1 0 0 1 1 1 0 Trehalose utilisation p450 PF00067.17 EPE28221.1 - 1.8e-48 165.2 0.1 2.4e-48 164.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rab3-GTPase_cat PF13890.1 EPE28222.1 - 0.022 14.1 0.1 0.045 13.1 0.1 1.6 1 1 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit DUF4660 PF15559.1 EPE28222.1 - 0.023 14.7 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) Troponin-I_N PF11636.3 EPE28222.1 - 0.097 12.3 0.3 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 Troponin I residues 1-32 Aldo_ket_red PF00248.16 EPE28223.1 - 8.7e-37 126.4 0.0 1.2e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.24 EPE28224.1 - 3.7e-15 56.2 0.0 1.3e-14 54.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EPE28224.1 - 0.00015 21.4 0.1 0.00043 19.9 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EPE28224.1 - 0.00081 20.2 0.2 0.0074 17.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE28224.1 - 0.00082 19.5 0.6 0.014 15.5 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EPE28224.1 - 0.00095 18.9 0.0 0.0028 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPE28224.1 - 0.03 14.3 1.2 0.11 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_C14 PF00656.17 EPE28225.1 - 6.9e-08 32.4 0.0 2e-07 30.9 0.0 1.5 1 1 1 2 2 2 1 Caspase domain Raptor_N PF14538.1 EPE28225.1 - 0.028 14.2 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF452 PF04301.8 EPE28225.1 - 0.06 12.6 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF452) DUF3169 PF11368.3 EPE28227.1 - 0.0047 16.1 1.8 0.0047 16.1 1.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) DUF4401 PF14351.1 EPE28227.1 - 0.0056 15.7 2.5 0.0081 15.1 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) Polysacc_synt PF01943.12 EPE28227.1 - 0.0058 15.9 3.4 0.0081 15.4 2.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ABC2_membrane_4 PF12730.2 EPE28227.1 - 0.0082 15.3 0.5 0.0082 15.3 0.4 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein TrbL PF04610.9 EPE28227.1 - 0.046 13.4 2.7 0.085 12.5 1.9 1.4 1 1 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF2207 PF09972.4 EPE28227.1 - 0.055 12.0 0.7 0.078 11.5 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1705 PF08019.7 EPE28227.1 - 0.11 12.0 5.8 0.19 11.2 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) YqhR PF11085.3 EPE28227.1 - 1.5 8.2 4.5 2.3 7.7 3.1 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR Ldh_1_N PF00056.18 EPE28228.1 - 1.6e-43 147.8 0.0 1.3e-42 144.9 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EPE28228.1 - 6.1e-43 146.5 0.0 1e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EPE28228.1 - 0.0033 16.1 0.0 0.0049 15.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EPE28228.1 - 0.081 13.2 0.4 0.47 10.7 0.0 2.4 2 1 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Pex14_N PF04695.8 EPE28229.1 - 0.1 12.6 0.3 0.15 12.0 0.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PGK PF00162.14 EPE28230.1 - 0.011 14.3 0.2 0.014 13.9 0.1 1.1 1 0 0 1 1 1 0 Phosphoglycerate kinase Pex14_N PF04695.8 EPE28230.1 - 0.038 14.0 0.1 0.065 13.2 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Myb_DNA-bind_4 PF13837.1 EPE28231.1 - 0.047 13.8 0.1 0.16 12.0 0.2 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EPE28231.1 - 0.056 14.0 0.2 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Rad60-SLD_2 PF13881.1 EPE28235.1 - 4.2e-09 36.2 0.0 2.1e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPE28235.1 - 0.0014 18.7 0.0 0.0037 17.4 0.0 1.8 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EPE28235.1 - 0.008 15.5 0.0 0.026 13.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family UMP1 PF05348.6 EPE28236.1 - 2.6e-20 72.7 0.0 3.4e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.22 EPE28237.1 - 8.6e-30 103.8 0.0 4.8e-16 59.3 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPE28237.1 - 4.8e-16 59.5 6.1 0.00012 22.1 0.0 4.0 3 1 0 3 3 3 3 AAA domain AAA_23 PF13476.1 EPE28237.1 - 3.9e-08 33.8 1.4 0.0064 16.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPE28237.1 - 1.2e-07 31.1 0.2 0.003 17.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EPE28237.1 - 2.6e-07 31.4 0.2 0.0043 17.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EPE28237.1 - 2.3e-06 27.7 0.1 0.034 14.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 EPE28237.1 - 2.6e-06 27.2 0.1 0.0071 16.2 0.1 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EPE28237.1 - 7.7e-06 25.5 0.4 0.021 14.2 0.1 2.8 3 0 0 3 3 3 2 AAA-like domain NACHT PF05729.7 EPE28237.1 - 1.6e-05 24.6 0.0 0.062 12.9 0.1 3.0 3 0 0 3 3 2 2 NACHT domain AAA_16 PF13191.1 EPE28237.1 - 2.3e-05 24.4 0.2 0.013 15.4 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EPE28237.1 - 7.8e-05 22.0 0.0 0.067 12.4 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EPE28237.1 - 0.00021 21.1 0.2 0.17 11.7 0.2 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EPE28237.1 - 0.00027 20.8 0.2 0.085 12.6 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EPE28237.1 - 0.00032 21.0 0.5 0.17 12.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EPE28237.1 - 0.00037 20.9 0.1 1.1 9.7 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 EPE28237.1 - 0.00062 19.2 0.1 0.02 14.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 EPE28237.1 - 0.00085 18.7 0.5 0.61 9.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.1 EPE28237.1 - 0.0009 18.8 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain ATP_bind_1 PF03029.12 EPE28237.1 - 0.0016 18.0 0.4 0.2 11.1 0.1 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 EPE28237.1 - 0.0023 17.9 0.2 1 9.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPE28237.1 - 0.0023 18.1 0.4 2 8.6 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EPE28237.1 - 0.0024 17.0 0.0 0.84 8.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EPE28237.1 - 0.0025 17.2 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EPE28237.1 - 0.0026 17.4 0.0 0.91 9.2 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EPE28237.1 - 0.0027 17.4 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase T2SE PF00437.15 EPE28237.1 - 0.0028 16.6 0.1 0.4 9.5 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 EPE28237.1 - 0.0073 15.8 0.1 0.62 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EPE28237.1 - 0.0082 15.8 1.4 0.63 9.7 0.1 2.8 3 0 0 3 3 3 1 NTPase ATP-synt_ab PF00006.20 EPE28237.1 - 0.011 15.1 0.0 0.52 9.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 EPE28237.1 - 0.011 15.5 0.1 8.5 6.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 EPE28237.1 - 0.013 15.7 0.2 5.2 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 EPE28237.1 - 0.015 14.9 0.2 3.5 7.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 EPE28237.1 - 0.016 15.1 0.0 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 EPE28237.1 - 0.017 14.8 1.3 1.3 8.8 0.2 2.7 2 0 0 2 2 2 0 Part of AAA domain Pox_A32 PF04665.7 EPE28237.1 - 0.021 14.1 0.0 0.27 10.4 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_15 PF13175.1 EPE28237.1 - 0.026 13.6 0.0 28 3.5 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain PduV-EutP PF10662.4 EPE28237.1 - 0.036 13.5 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EPE28237.1 - 0.081 11.7 1.0 9.5 4.9 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_13 PF13166.1 EPE28237.1 - 0.096 11.1 1.0 0.12 10.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EPE28237.1 - 0.24 10.4 0.9 13 4.7 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin SRPRB PF09439.5 EPE28237.1 - 0.33 10.1 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SRP54 PF00448.17 EPE28237.1 - 0.43 10.0 0.2 31 3.9 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MFS_1 PF07690.11 EPE28238.1 - 8.9e-25 87.1 29.2 1.2e-24 86.7 20.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Cir_N PF10197.4 EPE28238.1 - 0.36 10.8 4.0 0.84 9.7 2.8 1.6 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR MFS_1_like PF12832.2 EPE28238.1 - 1.5 8.6 13.1 0.092 12.5 0.5 2.6 2 0 0 2 2 2 0 MFS_1 like family CDC45 PF02724.9 EPE28238.1 - 2 6.3 6.2 2.9 5.8 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RTA1 PF04479.8 EPE28240.1 - 3.8e-37 127.9 4.1 5e-37 127.5 2.8 1.1 1 0 0 1 1 1 1 RTA1 like protein ABC_tran PF00005.22 EPE28241.1 - 1.1e-46 158.5 0.2 8.9e-23 81.0 0.0 4.4 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EPE28241.1 - 5.3e-18 65.9 0.1 0.00067 19.7 0.0 4.4 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 EPE28241.1 - 2e-17 63.1 0.0 1.7e-05 24.1 0.0 3.7 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPE28241.1 - 4.4e-10 38.9 0.0 0.0013 18.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EPE28241.1 - 2.1e-08 34.7 9.3 0.00013 22.3 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 EPE28241.1 - 3.4e-08 34.3 0.0 0.0025 18.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPE28241.1 - 7.5e-08 32.5 0.1 0.00093 19.3 0.0 3.5 4 0 0 4 4 2 2 AAA domain DUF258 PF03193.11 EPE28241.1 - 9.7e-08 31.3 0.0 0.00088 18.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EPE28241.1 - 1.9e-07 31.0 0.1 5.7e-05 22.9 0.0 2.9 2 1 0 2 2 2 1 Dynamin family AAA_15 PF13175.1 EPE28241.1 - 2.4e-07 30.1 0.6 0.24 10.4 0.0 4.0 4 1 0 4 4 4 3 AAA ATPase domain MMR_HSR1 PF01926.18 EPE28241.1 - 3.6e-07 30.1 0.0 0.0038 17.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 EPE28241.1 - 6e-07 29.5 0.1 0.0093 15.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EPE28241.1 - 3.4e-06 26.9 0.0 0.091 12.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPE28241.1 - 7.6e-06 26.2 0.3 0.18 12.1 0.0 3.7 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EPE28241.1 - 9.9e-06 25.2 0.2 0.26 10.6 0.0 3.3 4 0 0 4 4 3 2 AAA-like domain MobB PF03205.9 EPE28241.1 - 1.6e-05 24.6 0.0 0.25 11.0 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EPE28241.1 - 1.7e-05 24.6 0.0 0.16 11.9 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EPE28241.1 - 1.8e-05 25.2 0.1 0.079 13.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein ArgK PF03308.11 EPE28241.1 - 2.3e-05 23.2 0.1 0.2 10.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 EPE28241.1 - 3.9e-05 23.7 0.0 0.45 10.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 EPE28241.1 - 5.5e-05 23.3 0.1 0.38 10.9 0.1 4.1 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EPE28241.1 - 8.7e-05 22.3 0.2 0.46 10.1 0.0 3.4 4 0 0 4 4 2 2 Archaeal ATPase AAA_16 PF13191.1 EPE28241.1 - 9.1e-05 22.5 0.1 0.82 9.6 0.0 3.8 4 0 0 4 4 3 1 AAA ATPase domain NACHT PF05729.7 EPE28241.1 - 0.00021 20.9 0.0 0.089 12.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 EPE28241.1 - 0.00028 20.7 0.0 1.5 8.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 EPE28241.1 - 0.00069 19.1 0.0 0.97 8.9 0.0 3.1 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EPE28241.1 - 0.0012 18.4 0.0 4.6 6.7 0.0 3.7 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EPE28241.1 - 0.0015 18.0 0.1 1.4 8.3 0.0 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 EPE28241.1 - 0.0035 16.8 0.2 2.4 7.6 0.0 2.7 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain HEAT_2 PF13646.1 EPE28241.1 - 0.0042 17.3 3.7 11 6.3 0.0 3.2 2 1 1 3 3 2 0 HEAT repeats AAA_25 PF13481.1 EPE28241.1 - 0.0064 15.9 0.0 5 6.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EPE28241.1 - 0.0066 16.2 2.7 0.95 9.2 0.0 3.3 3 0 0 3 3 2 1 Domain of unknown function DUF87 MutS_V PF00488.16 EPE28241.1 - 0.0082 15.5 0.1 0.74 9.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain V Septin PF00735.13 EPE28241.1 - 0.014 14.4 0.1 1.8 7.4 0.0 2.8 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.12 EPE28241.1 - 0.021 14.3 0.2 7.7 5.9 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 EPE28241.1 - 0.022 14.2 0.1 2.5 7.5 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EPE28241.1 - 0.027 13.3 1.8 2 7.2 0.0 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_13 PF13166.1 EPE28241.1 - 0.028 12.9 10.8 1 7.6 0.0 4.3 5 0 0 5 5 4 0 AAA domain NB-ARC PF00931.17 EPE28241.1 - 0.038 12.8 0.0 0.44 9.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.16 EPE28241.1 - 0.044 12.9 0.0 3.7 6.6 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI PRK PF00485.13 EPE28241.1 - 0.046 13.2 0.0 1.6 8.2 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family V-ATPase_H_C PF11698.3 EPE28241.1 - 0.054 13.4 1.8 0.16 11.8 1.3 1.8 1 0 0 1 1 1 0 V-ATPase subunit H Pyr_redox_3 PF13738.1 EPE28242.1 - 3.5e-21 76.2 0.0 1.5e-20 74.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE28242.1 - 1.2e-11 43.5 0.0 4.1e-10 38.4 0.0 2.7 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPE28242.1 - 8.1e-10 38.1 0.1 8.5e-09 34.7 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPE28242.1 - 3.3e-09 36.9 0.0 1.4e-08 34.9 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE28242.1 - 1.2e-05 25.1 0.0 4.1e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPE28242.1 - 3.9e-05 23.4 0.1 0.028 14.1 0.0 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EPE28242.1 - 0.0019 17.1 0.0 0.0038 16.2 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EPE28242.1 - 0.0094 14.8 0.4 1.2 7.9 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPE28242.1 - 0.049 12.0 0.3 3.2 6.1 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.12 EPE28242.1 - 0.068 12.2 0.6 0.15 11.1 0.1 1.7 2 0 0 2 2 2 0 Thi4 family MoeA_N PF03453.12 EPE28242.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 MoeA N-terminal region (domain I and II) Pyr_redox PF00070.22 EPE28242.1 - 0.9 9.9 5.1 1.7 9.1 0.6 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AFG1_ATPase PF03969.11 EPE28245.1 - 1.7e-97 326.4 0.0 3.2e-92 309.1 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EPE28245.1 - 0.00016 21.7 0.1 0.19 11.6 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE28245.1 - 0.0028 17.8 0.0 0.0094 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPE28245.1 - 0.003 17.4 0.0 0.0079 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 EPE28245.1 - 0.0039 16.8 0.3 0.81 9.2 0.0 2.4 2 1 0 2 2 2 2 Bacterial dnaA protein NACHT PF05729.7 EPE28245.1 - 0.031 13.9 0.0 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EPE28245.1 - 0.04 13.6 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EPE28245.1 - 0.043 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EPE28245.1 - 0.048 13.6 0.0 0.53 10.3 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain CorA PF01544.13 EPE28247.1 - 0.055 12.4 0.0 0.18 10.8 0.0 1.9 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein R3H-assoc PF13902.1 EPE28249.1 - 4.1e-23 81.7 3.0 4.1e-23 81.7 2.1 1.6 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 EPE28249.1 - 5.3e-05 22.8 1.7 0.0003 20.4 0.1 2.6 2 1 0 2 2 2 1 R3H domain Peptidase_M28 PF04389.12 EPE28250.1 - 5.6e-26 91.3 0.1 1.1e-25 90.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EPE28250.1 - 0.00042 19.8 0.0 0.00074 19.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Frataxin_Cyay PF01491.11 EPE28250.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Frataxin-like domain zf-MYND PF01753.13 EPE28252.1 - 1.9e-05 24.4 13.2 1.9e-05 24.4 9.1 1.7 2 0 0 2 2 2 1 MYND finger UPF0137 PF03677.8 EPE28252.1 - 0.26 10.7 1.4 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0137) PolC_DP2 PF03833.8 EPE28252.1 - 0.28 8.7 1.5 0.4 8.2 1.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Melibiase PF02065.13 EPE28253.1 - 3.1e-21 75.5 0.1 8.2e-14 51.0 0.0 2.2 2 0 0 2 2 2 2 Melibiase Sugar_tr PF00083.19 EPE28255.1 - 2.3e-38 131.9 23.3 7.3e-38 130.2 16.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE28255.1 - 3.5e-36 124.6 41.5 1.1e-31 109.8 16.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EPE28255.1 - 0.0022 16.5 18.6 0.053 12.0 3.4 2.3 1 1 0 2 2 2 2 Vacuole effluxer Atg22 like Glyco_hydro_3 PF00933.16 EPE28256.1 - 3.4e-65 219.9 0.0 5.4e-65 219.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE28256.1 - 3e-43 147.9 0.0 4.1e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE28256.1 - 2.7e-05 24.0 0.0 6.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2324 PF10086.4 EPE28256.1 - 0.0052 16.0 0.0 0.0081 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative membrane peptidase family (DUF2324) DUF2823 PF11034.3 EPE28257.1 - 0.044 13.8 1.1 0.067 13.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2823) DUF3708 PF12501.3 EPE28257.1 - 0.084 12.7 0.1 0.084 12.7 0.1 1.6 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter FlxA PF14282.1 EPE28257.1 - 0.22 11.4 2.7 0.29 11.1 1.9 1.1 1 0 0 1 1 1 0 FlxA-like protein DUF3307 PF11750.3 EPE28258.1 - 0.058 13.1 1.7 0.089 12.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3307) Rhomboid PF01694.17 EPE28258.1 - 0.37 10.8 3.2 0.32 10.9 0.6 1.8 1 1 1 2 2 2 0 Rhomboid family RPN7 PF10602.4 EPE28264.1 - 0.00014 21.2 0.0 0.00038 19.8 0.0 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN7 AAA_16 PF13191.1 EPE28264.1 - 0.00035 20.5 0.1 0.0024 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.1 EPE28264.1 - 0.00059 19.7 1.7 0.029 14.3 0.1 2.6 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPE28264.1 - 0.00076 19.0 0.6 0.0043 16.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat NACHT PF05729.7 EPE28264.1 - 0.00084 19.0 0.0 0.0034 17.0 0.0 2.1 3 0 0 3 3 1 1 NACHT domain AAA_25 PF13481.1 EPE28264.1 - 0.0049 16.2 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain TPR_2 PF07719.12 EPE28264.1 - 0.0059 16.4 3.0 0.026 14.4 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat RNA_helicase PF00910.17 EPE28264.1 - 0.0084 16.2 0.0 0.033 14.3 0.0 2.1 1 0 0 1 1 1 1 RNA helicase DUF2075 PF09848.4 EPE28264.1 - 0.011 14.7 0.0 0.03 13.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EPE28264.1 - 0.012 15.3 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EPE28264.1 - 0.015 15.4 0.0 0.27 11.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain TPR_11 PF13414.1 EPE28264.1 - 0.015 14.9 2.7 0.023 14.3 0.1 2.4 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.1 EPE28264.1 - 0.022 14.4 0.7 0.057 13.2 0.0 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat CEP44 PF15007.1 EPE28264.1 - 0.028 14.1 0.1 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Centrosomal spindle body, CEP44 TPR_21 PF09976.4 EPE28264.1 - 0.028 14.3 3.9 0.075 12.9 2.7 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPE28264.1 - 0.034 13.7 0.1 0.14 11.8 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Torsin PF06309.6 EPE28264.1 - 0.042 13.7 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Torsin TPR_14 PF13428.1 EPE28264.1 - 0.044 14.4 2.6 2.7 8.8 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat IstB_IS21 PF01695.12 EPE28264.1 - 0.044 13.2 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SAS4 PF15460.1 EPE28264.1 - 0.074 12.9 0.0 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 ABC_tran PF00005.22 EPE28264.1 - 0.077 13.2 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 1 0 ABC transporter TPR_6 PF13174.1 EPE28264.1 - 0.18 12.3 1.0 0.93 10.0 0.7 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat PGAP1 PF07819.8 EPE28265.1 - 0.002 17.7 0.1 0.051 13.1 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EPE28265.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lactonase PF10282.4 EPE28267.1 - 1.1e-20 74.0 0.0 1.8e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1794 PF08768.6 EPE28267.1 - 0.75 9.6 3.3 0.65 9.8 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1794) Zn_clus PF00172.13 EPE28268.1 - 4.7e-08 32.8 11.8 1e-07 31.7 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.18 EPE28269.1 - 0.029 14.2 6.7 0.68 9.7 4.7 2.3 1 1 0 1 1 1 0 Membrane-associating domain DUF805 PF05656.9 EPE28269.1 - 0.75 9.6 5.6 0.16 11.8 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Cyd_oper_YbgE PF09600.5 EPE28269.1 - 3 8.0 5.9 0.91 9.7 0.1 2.7 2 1 1 3 3 3 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Glyco_hydro_3_C PF01915.17 EPE28270.1 - 1.8e-48 165.0 0.4 2.1e-47 161.5 0.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EPE28270.1 - 1.7e-40 138.8 0.0 3.1e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EPE28270.1 - 4.4e-18 64.9 0.0 8e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.16 EPE28271.1 - 7e-30 104.0 0.0 7.7e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Ank_2 PF12796.2 EPE28272.1 - 3.1e-109 357.5 27.5 1.6e-17 63.5 0.8 7.8 2 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EPE28272.1 - 4.2e-71 231.4 31.5 3.4e-07 29.7 0.1 15.9 16 0 0 16 16 15 11 Ankyrin repeat Ank_4 PF13637.1 EPE28272.1 - 2.8e-66 218.7 15.9 1.1e-08 35.3 0.1 12.6 8 4 6 14 14 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE28272.1 - 2.7e-56 181.8 19.4 8.7e-05 22.3 0.0 15.6 17 0 0 17 17 15 10 Ankyrin repeat Ank_5 PF13857.1 EPE28272.1 - 1.2e-53 177.9 26.3 5.2e-09 36.0 0.1 14.0 3 3 11 14 14 14 12 Ankyrin repeats (many copies) NACHT PF05729.7 EPE28272.1 - 4.7e-09 36.1 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EPE28272.1 - 2.5e-05 24.4 0.0 0.00013 22.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EPE28272.1 - 0.00017 20.5 0.0 0.00045 19.1 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 EPE28272.1 - 0.00038 20.3 0.1 0.04 13.8 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EPE28272.1 - 0.00045 20.4 0.5 0.0035 17.5 0.0 2.9 3 1 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE28272.1 - 0.0033 17.4 0.0 0.016 15.1 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EPE28272.1 - 0.0056 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase Viral_helicase1 PF01443.13 EPE28272.1 - 0.01 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EPE28272.1 - 0.014 15.5 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Torsin PF06309.6 EPE28272.1 - 0.036 13.9 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.1 EPE28272.1 - 0.1 12.4 0.0 0.39 10.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF2984 PF11203.3 EPE28272.1 - 0.28 11.3 5.3 11 6.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2984) DUF2611 PF11022.3 EPE28273.1 - 3.4e-21 75.1 4.3 1.6e-15 56.8 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2611) DUF1469 PF07332.6 EPE28273.1 - 0.01 15.5 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) MTP18 PF10558.4 EPE28274.1 - 3.4e-64 215.2 0.1 4.3e-64 214.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.11 EPE28275.1 - 6e-25 86.8 19.3 9.1e-13 47.8 4.3 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EPE28275.1 - 0.00018 21.3 14.3 0.0069 16.2 1.9 2.3 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 EPE28275.1 - 0.0015 18.6 10.8 0.15 12.3 1.7 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain C1_4 PF07975.7 EPE28275.1 - 5 7.2 17.1 9.6 6.3 2.2 2.8 2 1 0 2 2 2 0 TFIIH C1-like domain Acetyltransf_1 PF00583.19 EPE28276.1 - 0.0076 16.2 0.1 0.016 15.2 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE28276.1 - 0.011 15.8 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EPE28276.1 - 0.045 14.3 0.0 0.13 12.8 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PHP PF02811.14 EPE28277.1 - 2.2e-06 27.6 0.0 2.9e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 PHP domain MARVEL PF01284.18 EPE28278.1 - 5.3e-06 26.2 22.3 0.016 15.0 1.0 3.2 2 1 0 2 2 2 2 Membrane-associating domain UPF0233 PF06781.7 EPE28278.1 - 0.00067 19.2 1.6 2.5 7.7 0.0 3.6 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0233) Ank_2 PF12796.2 EPE28279.1 - 1.4e-10 41.3 0.0 5.4e-10 39.4 0.0 2.0 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) NACHT PF05729.7 EPE28279.1 - 3.1e-10 39.9 0.3 8.4e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Ank_5 PF13857.1 EPE28279.1 - 1.1e-07 31.8 0.0 6e-05 23.1 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE28279.1 - 2.4e-07 31.0 0.1 1.6e-06 28.4 0.0 2.6 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE28279.1 - 1e-06 28.3 0.0 0.0049 16.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 EPE28279.1 - 2.4e-06 27.0 0.0 0.0013 18.4 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat AAA_22 PF13401.1 EPE28279.1 - 0.00034 20.7 0.5 0.0018 18.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPE28279.1 - 0.0012 18.7 0.5 0.029 14.2 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPE28279.1 - 0.0015 18.5 4.0 0.0089 16.0 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EPE28279.1 - 0.0025 17.5 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase T2SE PF00437.15 EPE28279.1 - 0.011 14.6 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3365 PF11845.3 EPE28279.1 - 0.038 13.8 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) RNA_helicase PF00910.17 EPE28279.1 - 0.038 14.1 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.12 EPE28279.1 - 1.4 8.6 5.4 7.7 6.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAL_decarboxy PF03306.8 EPE28280.1 - 1e-68 230.6 0.1 1.2e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase TPP_enzyme_N PF02776.13 EPE28281.1 - 1.2e-45 155.0 1.1 6.1e-45 152.7 1.3 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EPE28281.1 - 8e-40 135.8 0.5 1.6e-39 134.9 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPE28281.1 - 2.6e-20 72.5 0.0 5.8e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain UDPG_MGDP_dh_N PF03721.9 EPE28282.1 - 1.1e-47 161.8 0.6 2e-31 108.8 0.1 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EPE28282.1 - 4.7e-32 110.0 0.0 9.1e-32 109.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EPE28282.1 - 3.4e-22 78.6 0.0 2.1e-17 63.2 0.0 3.1 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 EPE28282.1 - 0.00025 20.8 0.2 0.053 13.2 0.0 2.5 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EPE28282.1 - 0.046 12.6 0.0 0.088 11.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF2922 PF11148.3 EPE28282.1 - 0.1 12.2 0.0 1.2 8.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2922) ERM PF00769.14 EPE28283.1 - 0.00022 20.8 0.7 0.00022 20.8 0.5 3.5 2 1 1 3 3 3 1 Ezrin/radixin/moesin family DUF1664 PF07889.7 EPE28283.1 - 0.00065 19.4 25.6 0.033 14.0 3.7 4.4 2 2 2 4 4 4 2 Protein of unknown function (DUF1664) RAP1 PF07218.6 EPE28283.1 - 0.18 9.8 7.2 0.24 9.4 2.7 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Mitofilin PF09731.4 EPE28283.1 - 0.31 9.6 32.6 0.014 14.1 14.7 2.4 2 1 1 3 3 3 0 Mitochondrial inner membrane protein Apolipoprotein PF01442.13 EPE28283.1 - 0.88 9.0 37.0 5.2 6.5 19.8 3.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EPE28283.1 - 0.93 9.3 16.6 1.9 8.3 4.2 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3348 PF11828.3 EPE28283.1 - 1 8.7 13.7 0.23 10.8 6.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3348) DUF4407 PF14362.1 EPE28283.1 - 1.8 7.4 16.2 4.4 6.1 11.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.8 EPE28283.1 - 2.5 8.5 20.3 2.9 8.3 2.0 3.9 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF342 PF03961.8 EPE28283.1 - 3.7 5.8 27.6 0.97 7.7 12.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF342) TBPIP PF07106.8 EPE28283.1 - 6.3 6.3 38.7 0.13 11.8 8.4 4.0 2 2 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Borrelia_P83 PF05262.6 EPE28283.1 - 7.4 4.7 19.8 14 3.8 13.7 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Mnd1 PF03962.10 EPE28283.1 - 8.2 6.0 34.1 1.1 8.8 16.9 2.9 2 1 0 2 2 2 0 Mnd1 family IncA PF04156.9 EPE28283.1 - 9.5 5.7 35.4 14 5.1 4.6 3.2 2 1 1 3 3 3 0 IncA protein LIP PF03583.9 EPE28284.1 - 0.23 10.6 5.2 0.069 12.3 1.2 1.6 1 1 1 2 2 2 0 Secretory lipase Fzo_mitofusin PF04799.8 EPE28284.1 - 0.42 9.9 31.0 0.88 8.9 6.1 3.2 1 1 2 3 3 3 0 fzo-like conserved region AAA_13 PF13166.1 EPE28284.1 - 0.71 8.2 31.8 0.87 7.9 22.0 1.1 1 0 0 1 1 1 0 AAA domain Sds3 PF08598.6 EPE28284.1 - 2.4 7.6 26.6 4 6.9 18.4 1.4 1 0 0 1 1 1 0 Sds3-like ApoO PF09769.4 EPE28284.1 - 2.6 7.7 13.5 1.2 8.7 1.0 2.7 1 1 2 3 3 3 0 Apolipoprotein O DUF3452 PF11934.3 EPE28284.1 - 3.2 7.0 16.9 2.3 7.5 9.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) DUF3337 PF11816.3 EPE28284.1 - 3.9 6.7 21.8 6.3 6.0 14.9 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3337) CCDC84 PF14968.1 EPE28284.1 - 4.4 6.7 18.8 6.3 6.1 13.0 1.4 1 0 0 1 1 1 0 Coiled coil protein 84 Peptidase_S46 PF10459.4 EPE28284.1 - 4.7 5.5 27.2 5.3 5.3 18.9 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF3086 PF11285.3 EPE28284.1 - 5.1 5.8 21.3 1 8.1 12.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Apolipoprotein PF01442.13 EPE28284.1 - 6.1 6.2 36.2 11 5.4 25.1 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Allexi_40kDa PF05549.6 EPE28284.1 - 8.7 5.5 25.6 0.41 9.9 5.6 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein HNH_2 PF13391.1 EPE28286.1 - 2.9e-05 23.7 0.0 5.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF1664 PF07889.7 EPE28286.1 - 0.096 12.4 1.3 0.17 11.6 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 EPE28286.1 - 0.11 12.1 0.7 0.17 11.4 0.5 1.2 1 0 0 1 1 1 0 IncA protein TBPIP PF07106.8 EPE28286.1 - 0.13 11.8 2.6 0.21 11.1 1.8 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3847 PF12958.2 EPE28286.1 - 0.42 10.4 3.7 0.49 10.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) COG5 PF10392.4 EPE28287.1 - 0.0018 18.2 0.2 0.0025 17.7 0.1 1.1 1 0 0 1 1 1 1 Golgi transport complex subunit 5 AATF-Che1 PF13339.1 EPE28287.1 - 0.0061 16.7 0.1 0.0074 16.4 0.1 1.1 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor SlyX PF04102.7 EPE28287.1 - 0.084 13.2 1.8 0.15 12.4 1.2 1.4 1 0 0 1 1 1 0 SlyX MutS_III PF05192.13 EPE28289.1 - 0.0041 16.9 0.2 0.0044 16.8 0.1 1.1 1 0 0 1 1 1 1 MutS domain III Cast PF10174.4 EPE28289.1 - 0.012 13.7 7.3 0.016 13.3 5.1 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Med30 PF11315.3 EPE28289.1 - 0.016 15.3 1.3 0.016 15.3 0.9 2.0 2 0 0 2 2 2 0 Mediator complex subunit 30 FUSC PF04632.7 EPE28289.1 - 0.11 10.9 1.5 0.14 10.5 1.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family WASH-7_mid PF14744.1 EPE28289.1 - 0.16 10.8 2.2 0.21 10.3 1.5 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 Rootletin PF15035.1 EPE28289.1 - 0.26 11.2 13.4 0.48 10.3 9.3 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF2730 PF10805.3 EPE28289.1 - 0.34 10.6 2.6 1.2 8.9 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) LRR_4 PF12799.2 EPE28289.1 - 0.36 10.4 2.1 0.52 9.9 0.2 2.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Filament PF00038.16 EPE28289.1 - 0.49 9.8 11.1 1.9 7.8 7.7 1.7 1 1 0 1 1 1 0 Intermediate filament protein YlbD_coat PF14071.1 EPE28289.1 - 2.8 8.0 9.6 20 5.2 5.1 2.3 1 1 1 2 2 2 0 Putative coat protein Baculo_p24 PF05073.7 EPE28289.1 - 3.3 7.2 8.4 2.7 7.5 1.5 2.2 1 1 1 2 2 2 0 Baculovirus P24 capsid protein CorA PF01544.13 EPE28289.1 - 8 5.3 8.8 4.1 6.3 3.9 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-C2H2 PF00096.21 EPE28292.1 - 3.2e-15 55.4 90.7 0.0031 17.7 0.1 15.9 16 0 0 16 16 16 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE28292.1 - 6.8e-12 44.8 77.5 0.015 15.5 0.0 14.8 16 0 0 16 16 16 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPE28292.1 - 4.3e-08 32.7 50.4 0.0002 21.1 0.0 11.4 12 0 0 12 12 12 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE28292.1 - 8.5e-08 32.1 76.8 0.055 13.7 0.3 13.9 13 1 0 13 13 13 6 Zinc-finger double domain zf-C2HC_2 PF13913.1 EPE28292.1 - 0.00061 19.3 0.0 0.00061 19.3 0.0 8.0 7 0 0 7 7 7 1 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 EPE28292.1 - 0.0046 17.0 3.9 0.0046 17.0 2.7 10.6 12 0 0 12 12 12 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EPE28292.1 - 0.12 12.6 0.0 0.12 12.6 0.0 13.6 15 0 0 15 15 15 0 Zinc-finger double-stranded RNA-binding Yippee-Mis18 PF03226.9 EPE28292.1 - 1.1 9.3 25.8 0.31 11.1 0.7 5.6 5 0 0 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Rad50_zn_hook PF04423.9 EPE28292.1 - 4.9 6.7 9.5 20 4.7 0.0 4.4 4 0 0 4 4 4 0 Rad50 zinc hook motif Methyltransf_2 PF00891.13 EPE28293.1 - 6.4e-33 113.9 0.0 8.1e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Sigma70_r4 PF04545.11 EPE28293.1 - 0.024 13.9 0.0 0.059 12.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 BCDHK_Adom3 PF10436.4 EPE28294.1 - 1.5e-46 157.9 0.0 2.1e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EPE28294.1 - 1.3e-15 57.0 0.0 1.5e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EPE28294.1 - 0.036 13.7 0.0 0.27 10.8 0.0 2.2 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EPE28294.1 - 0.093 12.5 0.0 0.29 10.9 0.0 1.9 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Inhibitor_I9 PF05922.11 EPE28295.1 - 0.022 15.3 0.0 0.022 15.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase inhibitor I9 DUF663 PF04950.7 EPE28296.1 - 1.3e-88 296.8 0.0 2.9e-88 295.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EPE28296.1 - 5.4e-28 96.3 0.0 4.5e-27 93.4 0.0 2.6 3 0 0 3 3 3 1 AARP2CN (NUC121) domain AAA_22 PF13401.1 EPE28296.1 - 1.3e-05 25.3 0.0 3.8e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPE28296.1 - 1.4e-05 25.1 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 EPE28296.1 - 1.7e-05 24.3 0.0 0.011 15.2 0.0 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain NACHT PF05729.7 EPE28296.1 - 0.00014 21.5 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EPE28296.1 - 0.00018 22.2 0.0 0.00018 22.2 0.0 4.7 3 1 1 4 4 2 1 AAA domain Miro PF08477.8 EPE28296.1 - 0.00029 21.2 0.0 0.0013 19.2 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_33 PF13671.1 EPE28296.1 - 0.0004 20.2 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EPE28296.1 - 0.00054 19.4 0.0 0.0016 17.9 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EPE28296.1 - 0.0006 20.0 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EPE28296.1 - 0.00074 19.4 0.0 0.0022 17.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EPE28296.1 - 0.0014 18.0 0.0 0.0041 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPE28296.1 - 0.0016 18.7 0.0 0.0016 18.7 0.0 4.3 3 1 1 4 4 2 1 AAA domain AAA_19 PF13245.1 EPE28296.1 - 0.002 17.8 0.0 0.0063 16.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 EPE28296.1 - 0.0023 17.4 0.1 0.0058 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 EPE28296.1 - 0.003 17.2 0.3 0.014 15.0 0.2 2.2 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EPE28296.1 - 0.003 17.8 2.2 0.0058 16.9 0.0 2.6 3 0 0 3 3 2 1 ABC transporter AAA_14 PF13173.1 EPE28296.1 - 0.0031 17.4 0.0 0.01 15.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPE28296.1 - 0.0064 16.6 0.1 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.1 EPE28296.1 - 0.0074 15.8 0.1 0.021 14.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EPE28296.1 - 0.0084 14.9 0.1 0.03 13.1 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain DUF258 PF03193.11 EPE28296.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EPE28296.1 - 0.014 15.1 0.3 0.029 14.0 0.2 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.14 EPE28296.1 - 0.02 14.3 0.1 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.10 EPE28296.1 - 0.024 13.3 1.5 0.23 10.0 0.0 2.5 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 EPE28296.1 - 0.035 13.8 0.5 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRPRB PF09439.5 EPE28296.1 - 0.26 10.4 0.0 0.26 10.4 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ADH_zinc_N PF00107.21 EPE28297.1 - 8.5e-20 70.6 0.2 1.5e-19 69.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE28297.1 - 5.3e-09 37.0 0.1 1.4e-08 35.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE28297.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DHC_N2 PF08393.8 EPE28298.1 - 0.0097 14.4 0.2 0.014 13.8 0.1 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_16 PF13191.1 EPE28299.1 - 7.1e-10 39.1 0.0 3e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EPE28299.1 - 6e-08 32.5 0.0 1.5e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EPE28299.1 - 0.00012 22.1 0.2 0.00039 20.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EPE28299.1 - 0.00013 21.1 0.0 0.00049 19.2 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.17 EPE28299.1 - 0.0002 20.3 0.1 0.00043 19.2 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain KaiC PF06745.8 EPE28299.1 - 0.00021 20.5 0.2 0.00069 18.8 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA PF00004.24 EPE28299.1 - 0.00055 20.1 2.8 0.011 15.9 0.0 3.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE28299.1 - 0.0011 19.8 0.3 0.012 16.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EPE28299.1 - 0.0023 17.6 0.0 0.017 14.8 0.0 2.3 2 1 0 2 2 2 1 Part of AAA domain KAP_NTPase PF07693.9 EPE28299.1 - 0.0023 16.9 4.5 0.0053 15.7 0.0 2.5 2 1 1 3 3 3 1 KAP family P-loop domain CCDC92 PF14916.1 EPE28299.1 - 0.01 15.4 0.3 0.024 14.2 0.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function AAA_33 PF13671.1 EPE28299.1 - 0.011 15.6 0.4 0.047 13.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EPE28299.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Methyltransf_32 PF13679.1 EPE28299.1 - 0.016 14.9 0.0 0.04 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AAA_14 PF13173.1 EPE28299.1 - 0.018 14.9 0.1 0.11 12.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EPE28299.1 - 0.025 13.5 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.6 EPE28299.1 - 0.039 13.8 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 Torsin SAP30_Sin3_bdg PF13867.1 EPE28299.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 IMD PF08397.6 EPE28299.1 - 0.067 12.4 2.7 2 7.6 0.3 2.3 2 0 0 2 2 2 0 IRSp53/MIM homology domain AAA_30 PF13604.1 EPE28299.1 - 0.073 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain FlaC_arch PF05377.6 EPE28299.1 - 0.37 10.7 2.4 0.56 10.1 0.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) MRP PF09387.5 EPE28301.1 - 0.0048 16.6 0.0 2 8.1 0.0 2.4 1 1 1 2 2 2 2 Mitochondrial RNA binding protein MRP Viral_P18 PF04521.8 EPE28301.1 - 0.26 10.7 4.3 0.16 11.4 0.3 2.4 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein Cyclase PF04199.8 EPE28302.1 - 7.9e-17 61.4 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase NSs PF11073.3 EPE28302.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like Sugar_tr PF00083.19 EPE28303.1 - 1.9e-115 386.0 25.3 2.2e-115 385.8 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE28303.1 - 8.8e-24 83.8 46.4 2.1e-17 62.8 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RBDV_coat PF06593.6 EPE28304.1 - 0.032 13.4 1.7 0.06 12.5 0.9 1.6 1 1 1 2 2 2 0 Raspberry bushy dwarf virus coat protein Ribosomal_L28e PF01778.12 EPE28304.1 - 1.1 9.6 6.7 6.5 7.1 4.7 2.0 1 1 0 1 1 1 0 Ribosomal L28e protein family MFS_1 PF07690.11 EPE28305.1 - 1.6e-29 102.7 28.5 2.4e-29 102.1 19.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_2 PF12796.2 EPE28306.1 - 1.4e-49 166.3 1.6 1.1e-16 60.8 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPE28306.1 - 1.3e-40 135.2 13.7 6.6e-08 31.9 0.0 8.6 7 2 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.1 EPE28306.1 - 1.6e-36 120.6 4.5 7.6e-05 22.5 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 EPE28306.1 - 2e-35 120.5 2.2 1.6e-16 60.3 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE28306.1 - 2.9e-26 90.8 9.3 9.3e-08 32.0 0.1 6.8 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 EPE28307.1 - 3.1e-23 80.3 0.4 2.2e-07 30.3 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EPE28307.1 - 6.9e-23 80.7 0.4 1.2e-12 47.9 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPE28307.1 - 5.1e-18 63.3 0.1 0.00032 20.6 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EPE28307.1 - 1.5e-16 60.4 0.2 4.2e-06 27.1 0.0 3.6 3 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE28307.1 - 6e-14 51.7 0.5 4.7e-05 23.4 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) TES PF08034.6 EPE28309.1 - 0.0012 18.8 0.4 0.0026 17.7 0.3 1.4 1 0 0 1 1 1 1 Trematode eggshell synthesis protein UreE_N PF02814.10 EPE28310.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Pyr_redox_3 PF13738.1 EPE28311.1 - 1.4e-11 44.8 0.0 2.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE28311.1 - 3.5e-06 26.9 0.0 7.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EPE28311.1 - 5e-05 22.5 0.0 7.4e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EPE28311.1 - 0.00015 20.9 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EPE28311.1 - 0.0026 17.6 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE28311.1 - 0.0065 16.8 0.0 0.1 13.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE28311.1 - 0.0066 15.3 0.2 0.01 14.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE28311.1 - 0.0083 15.0 0.3 0.013 14.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EPE28311.1 - 0.0098 14.8 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EPE28311.1 - 0.022 13.2 0.0 0.03 12.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 EPE28311.1 - 0.039 13.9 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain SnoaL_2 PF12680.2 EPE28311.1 - 0.058 13.8 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain Shikimate_DH PF01488.15 EPE28311.1 - 0.098 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4585 PF15232.1 EPE28312.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) SIR2 PF02146.12 EPE28313.1 - 3.4e-28 98.5 0.0 3.9e-10 39.7 0.0 3.3 2 1 1 3 3 3 3 Sir2 family zf-CHY PF05495.7 EPE28314.1 - 3.8e-14 52.5 7.3 5.1e-14 52.1 5.0 1.1 1 0 0 1 1 1 1 CHY zinc finger DUF3133 PF11331.3 EPE28314.1 - 0.017 14.6 5.6 0.019 14.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) TACI-CRD2 PF09305.5 EPE28314.1 - 0.029 14.1 0.5 0.26 11.0 0.0 2.4 2 0 0 2 2 2 0 TACI, cysteine-rich domain Cytochrome_C7 PF14522.1 EPE28314.1 - 0.36 10.4 8.0 1.3 8.7 5.5 1.9 1 1 0 1 1 1 0 Cytochrome c7 DZR PF12773.2 EPE28314.1 - 2.4 8.0 9.8 31 4.4 6.8 2.4 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 EPE28314.1 - 7.3 6.2 7.9 19 4.9 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain CENP-L PF13092.1 EPE28316.1 - 1.7e-39 135.1 0.0 2.2e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 peroxidase PF00141.18 EPE28317.1 - 1.2e-27 96.9 0.2 1.8e-27 96.3 0.2 1.3 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EPE28317.1 - 0.0005 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) DUF1774 PF08611.5 EPE28318.1 - 1e-34 118.5 3.4 1e-34 118.5 2.4 2.6 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Zn_clus PF00172.13 EPE28319.1 - 7.1e-08 32.2 8.8 1.2e-07 31.5 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE28319.1 - 1.8e-05 23.7 0.1 3.8e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain SGL PF08450.7 EPE28320.1 - 1e-23 83.9 0.0 2.9e-23 82.5 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PM0188 PF11477.3 EPE28322.1 - 0.0009 18.1 0.9 0.0012 17.7 0.6 1.1 1 0 0 1 1 1 1 Sialyltransferase PMO188 Prominin PF05478.6 EPE28322.1 - 0.076 10.5 0.2 0.9 6.9 0.0 1.8 1 1 1 2 2 2 0 Prominin Occludin_ELL PF07303.8 EPE28322.1 - 0.11 13.2 7.9 0.23 12.1 3.9 2.5 1 1 1 2 2 2 0 Occludin homology domain THOC7 PF05615.8 EPE28322.1 - 1.2 9.4 9.4 0.38 11.0 1.8 2.7 1 1 2 3 3 3 0 Tho complex subunit 7 HALZ PF02183.13 EPE28324.1 - 0.13 11.9 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Acylphosphatase PF00708.13 EPE28330.1 - 1.5e-27 95.5 0.2 1.6e-27 95.3 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase F-box-like PF12937.2 EPE28331.1 - 5.9e-05 22.7 0.1 0.00022 20.8 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE28331.1 - 9.3e-05 21.9 0.2 0.00039 19.9 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE28332.1 - 0.053 13.2 1.5 0.078 12.7 0.1 2.1 2 0 0 2 2 2 0 F-box-like PTPA PF03095.10 EPE28332.1 - 0.06 12.5 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein Glyco_hydro_cc PF11790.3 EPE28333.1 - 1.4e-71 240.7 0.4 1.6e-71 240.5 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF1G PF00647.14 EPE28333.1 - 0.11 12.1 0.4 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain Thiolase_N PF00108.18 EPE28334.1 - 2.8e-75 252.7 0.2 5.1e-75 251.8 0.1 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPE28334.1 - 2.4e-40 136.7 0.8 4.1e-40 136.0 0.1 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EPE28334.1 - 0.01 15.4 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EPE28334.1 - 0.046 13.1 2.8 0.14 11.6 1.4 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 EPE28334.1 - 0.065 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SepQ PF06622.6 EPE28335.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 SepQ protein Lactamase_B_2 PF12706.2 EPE28336.1 - 2.5e-21 76.1 0.0 3.2e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPE28336.1 - 6.7e-07 29.1 0.2 1.5e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Isochorismatase PF00857.15 EPE28339.1 - 9.1e-41 139.6 0.0 1e-40 139.4 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family OTU PF02338.14 EPE28340.1 - 5.2e-12 46.4 0.0 3e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 OTU-like cysteine protease CUE PF02845.11 EPE28340.1 - 0.006 16.0 0.1 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain SLAC1 PF03595.12 EPE28341.1 - 1.1e-65 221.4 49.1 1.3e-65 221.2 34.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Senescence PF06911.7 EPE28342.1 - 3.6e-46 157.1 10.7 5.2e-46 156.5 7.4 1.2 1 0 0 1 1 1 1 Senescence-associated protein Fungal_trans PF04082.13 EPE28343.1 - 1.4e-25 89.6 0.0 2.9e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE28343.1 - 3.7e-05 23.5 8.9 7.2e-05 22.6 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spc97_Spc98 PF04130.8 EPE28344.1 - 4.3e-65 220.0 0.0 6.1e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF1835 PF08874.5 EPE28345.1 - 0.15 12.0 0.4 0.31 10.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) Thioredoxin PF00085.15 EPE28346.1 - 1.1e-29 102.2 0.2 1.2e-29 102.0 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 EPE28346.1 - 1e-07 31.5 0.1 1.2e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EPE28346.1 - 4.6e-07 30.0 0.9 5.7e-06 26.4 0.6 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPE28346.1 - 5.2e-07 29.7 0.1 1.6e-06 28.1 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.11 EPE28346.1 - 3.4e-05 22.6 0.0 3.9e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Phosducin Redoxin PF08534.5 EPE28346.1 - 4.2e-05 23.1 0.6 0.0024 17.4 0.3 2.0 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 EPE28346.1 - 0.00066 19.3 0.3 0.0022 17.6 0.2 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EPE28346.1 - 0.0017 18.3 0.1 0.0033 17.4 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.10 EPE28346.1 - 0.0027 17.4 0.5 0.0056 16.4 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_4 PF13462.1 EPE28346.1 - 0.081 12.9 0.2 0.16 11.9 0.0 1.5 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.19 EPE28346.1 - 0.13 12.2 0.5 0.27 11.2 0.4 1.6 1 1 0 1 1 1 0 Glutaredoxin Dsh_C PF12316.3 EPE28347.1 - 0.51 10.4 4.6 0.54 10.3 3.2 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Methyltransf_2 PF00891.13 EPE28348.1 - 3.8e-26 91.7 0.0 6e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EPE28348.1 - 0.11 12.3 4.4 0.11 12.4 0.6 2.7 2 1 0 2 2 2 0 Dimerisation domain COPI_assoc PF08507.5 EPE28349.1 - 2.3e-38 131.0 4.5 2.5e-38 130.8 3.1 1.0 1 0 0 1 1 1 1 COPI associated protein Neurensin PF14927.1 EPE28349.1 - 0.016 14.5 1.0 0.016 14.5 0.7 1.7 1 1 1 2 2 2 0 Neurensin Cg6151-P PF10233.4 EPE28349.1 - 0.021 14.7 3.4 0.033 14.1 2.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P UCR_Fe-S_N PF10399.4 EPE28349.1 - 0.15 11.2 0.3 0.25 10.5 0.2 1.3 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF2583 PF10762.4 EPE28349.1 - 1.1 9.4 3.6 20 5.4 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Acyltransferase PF01553.16 EPE28350.1 - 2.1e-16 59.5 0.0 7.9e-16 57.6 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase UPF0086 PF01868.11 EPE28351.1 - 1.2e-19 69.7 0.5 1.9e-19 69.0 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Fungal_trans_2 PF11951.3 EPE28352.1 - 1.3e-11 43.7 4.1 1.4e-10 40.3 2.9 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE28352.1 - 4.7e-07 29.6 9.4 9e-07 28.7 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 EPE28353.1 - 2.1e-23 83.0 0.0 4.9e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 EPE28353.1 - 7.5e-14 50.9 3.5 0.021 14.7 0.0 6.2 5 2 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_C550 PF14495.1 EPE28354.1 - 0.045 13.2 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain PQ-loop PF04193.9 EPE28355.1 - 7.4e-12 44.6 1.4 7.4e-12 44.6 1.0 2.1 1 1 1 2 2 2 1 PQ loop repeat Hemerythrin PF01814.18 EPE28356.1 - 1.4e-10 41.4 0.8 1.9e-10 40.9 0.4 1.4 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Afaf PF15339.1 EPE28356.1 - 0.042 13.4 0.1 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor XAP5 PF04921.9 EPE28357.1 - 6.5e-79 264.8 0.0 9.9e-79 264.2 0.0 1.3 1 0 0 1 1 1 1 XAP5, circadian clock regulator TPR_11 PF13414.1 EPE28358.1 - 5.8e-12 45.0 2.9 1.2e-11 44.1 1.1 2.0 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EPE28358.1 - 4.9e-07 29.0 3.6 0.00019 20.8 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPE28358.1 - 5.9e-07 28.9 2.3 0.0048 16.7 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPE28358.1 - 6.2e-06 26.0 1.0 1.6e-05 24.7 0.7 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE28358.1 - 0.0011 18.6 1.2 0.48 10.3 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPE28358.1 - 0.0025 18.3 1.0 0.068 13.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EPE28358.1 - 0.01 15.9 1.1 0.02 15.0 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EPE28358.1 - 0.15 12.7 2.6 0.54 11.0 0.5 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2229 PF09989.4 EPE28358.1 - 1.3 8.3 4.8 0.77 9.1 0.8 2.0 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) TPR_6 PF13174.1 EPE28358.1 - 5.5 7.6 5.4 24 5.6 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat HAD_2 PF13419.1 EPE28359.1 - 1.7e-11 44.6 0.0 2.5e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPE28359.1 - 4.8e-06 27.1 0.0 0.00097 19.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE28359.1 - 4.9e-05 22.9 0.0 8.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF1722 PF08349.6 EPE28361.1 - 0.01 15.6 0.0 0.021 14.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1722) Acetyltransf_10 PF13673.1 EPE28362.1 - 6.9e-05 22.9 0.0 0.00015 21.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE28362.1 - 0.0001 22.2 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE28362.1 - 0.0062 16.6 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE28362.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 EPE28362.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Ribosomal_S24e PF01282.14 EPE28362.1 - 0.052 13.3 0.0 0.7 9.7 0.0 2.3 3 0 0 3 3 3 0 Ribosomal protein S24e DUF3112 PF11309.3 EPE28363.1 - 1.6e-45 154.7 5.3 1.6e-45 154.7 3.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) DUF1643 PF07799.7 EPE28363.1 - 0.016 14.8 0.1 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Metallophos PF00149.23 EPE28364.1 - 4.8e-44 150.1 0.9 6.1e-44 149.8 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vps51 PF08700.6 EPE28365.1 - 5.4e-16 58.2 4.3 1.5e-15 56.7 3.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 EPE28365.1 - 0.021 14.6 2.3 0.16 11.8 0.3 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 EPE28365.1 - 6.8 6.2 7.6 0.84 9.1 1.4 2.2 2 1 0 2 2 2 0 IncA protein MAS20 PF02064.10 EPE28366.1 - 6.9e-17 61.4 1.1 3.6e-12 46.2 0.9 2.7 2 1 0 2 2 2 2 MAS20 protein import receptor Frankia_peptide PF14407.1 EPE28366.1 - 0.028 14.1 0.4 0.062 13.0 0.3 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. PMC2NT PF08066.7 EPE28366.1 - 0.039 14.2 0.1 0.067 13.4 0.1 1.3 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DHC_N1 PF08385.7 EPE28367.1 - 1.5e-195 651.0 4.7 1.5e-195 651.0 3.3 4.4 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EPE28367.1 - 2.1e-130 434.8 6.8 2.1e-130 434.8 4.7 4.6 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EPE28367.1 - 1.3e-104 350.6 0.2 4.1e-104 349.0 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EPE28367.1 - 2.3e-78 262.9 0.0 5.9e-78 261.5 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 EPE28367.1 - 7.1e-44 149.7 2.4 1.2e-42 145.7 0.3 3.5 3 1 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 EPE28367.1 - 1.5e-42 145.0 0.2 6.2e-42 142.9 0.1 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 EPE28367.1 - 1.4e-40 139.1 6.0 1.4e-40 139.1 4.1 2.4 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EPE28367.1 - 3.3e-32 111.1 2.2 2.2e-11 43.6 0.0 7.5 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EPE28367.1 - 1.9e-20 73.0 0.0 1.6e-18 66.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EPE28367.1 - 5.7e-15 55.6 0.0 0.012 15.7 0.0 5.9 4 0 0 4 4 4 3 AAA domain AAA PF00004.24 EPE28367.1 - 3e-13 50.0 0.0 0.0019 18.3 0.0 4.9 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EPE28367.1 - 3.6e-10 39.8 0.2 0.36 10.7 0.0 5.2 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 EPE28367.1 - 4.3e-10 40.4 2.4 0.032 15.0 0.0 6.6 6 0 0 6 6 5 2 AAA domain AAA_18 PF13238.1 EPE28367.1 - 2.1e-09 37.7 3.8 0.021 15.1 0.0 6.2 6 0 0 6 6 6 2 AAA domain T2SE PF00437.15 EPE28367.1 - 3.3e-07 29.4 0.0 0.052 12.4 0.0 3.8 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_16 PF13191.1 EPE28367.1 - 9.7e-07 28.9 12.3 0.15 12.0 0.1 7.6 6 2 1 7 7 6 2 AAA ATPase domain Mg_chelatase PF01078.16 EPE28367.1 - 5.3e-06 25.7 0.9 0.5 9.4 0.0 4.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EPE28367.1 - 6.1e-06 25.8 0.1 0.87 9.3 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain AAA_29 PF13555.1 EPE28367.1 - 1.2e-05 24.7 0.0 1.8 8.1 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_tran PF00005.22 EPE28367.1 - 2.3e-05 24.7 0.1 2.7 8.3 0.0 5.0 3 0 0 3 3 3 2 ABC transporter FtsK_SpoIIIE PF01580.13 EPE28367.1 - 0.0012 18.4 0.8 16 4.9 0.0 4.2 4 0 0 4 4 3 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EPE28367.1 - 0.0012 18.2 1.1 0.36 10.2 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.1 EPE28367.1 - 0.004 16.5 0.4 0.41 10.0 0.0 3.9 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 EPE28367.1 - 0.0049 17.0 0.1 19 5.4 0.0 4.7 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 EPE28367.1 - 0.032 13.9 0.3 11 5.6 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ERM PF00769.14 EPE28367.1 - 0.57 9.6 25.9 0.44 10.0 7.7 3.0 3 0 0 3 3 3 0 Ezrin/radixin/moesin family AAA_10 PF12846.2 EPE28367.1 - 1.1 8.5 12.1 5.5 6.3 0.1 5.0 6 0 0 6 6 5 0 AAA-like domain CorA PF01544.13 EPE28369.1 - 6.7e-10 38.4 1.2 1.7e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Orbi_NS3 PF01616.11 EPE28369.1 - 0.023 13.6 0.5 1.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Orbivirus NS3 DUF2203 PF09969.4 EPE28369.1 - 4.1 7.6 6.8 21 5.3 0.4 3.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Histone PF00125.19 EPE28370.1 - 1.9e-12 47.1 0.1 2.8e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPE28370.1 - 5.6e-07 29.5 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EPE28370.1 - 0.00018 21.3 0.1 0.00018 21.3 0.0 1.5 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TFIID-18kDa PF02269.11 EPE28370.1 - 0.0025 17.5 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 EPE28370.1 - 0.025 14.7 0.1 0.042 14.0 0.0 1.4 1 1 0 1 1 1 0 Kinetochore component CENP-S TFIID-31kDa PF02291.10 EPE28370.1 - 0.084 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 EPE28370.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Svf1 PF08622.5 EPE28371.1 - 2.5e-127 424.3 0.3 2.9e-127 424.1 0.2 1.0 1 0 0 1 1 1 1 Svf1-like DUF2231 PF09990.4 EPE28372.1 - 9.5e-08 32.3 0.2 1.6e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) HTH_23 PF13384.1 EPE28375.1 - 0.09 12.4 0.0 0.51 10.0 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Cpn10 PF00166.16 EPE28376.1 - 1.7e-25 88.7 0.0 1.9e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.20 EPE28377.1 - 2.7e-59 200.4 0.0 3.9e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE28377.1 - 2.1e-21 76.2 0.0 4.7e-20 71.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EPE28377.1 - 0.0033 17.1 0.0 0.0077 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.9 EPE28378.1 - 5.4e-26 89.8 0.1 8e-26 89.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EPE28378.1 - 5.6e-17 61.6 0.2 1e-16 60.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF4267 PF14087.1 EPE28380.1 - 4e-19 68.2 4.6 4.5e-19 68.0 3.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) MoCF_biosynth PF00994.19 EPE28381.1 - 1.2e-55 186.9 1.1 1.1e-30 105.9 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EPE28381.1 - 5.5e-36 123.3 2.1 8.6e-36 122.7 1.4 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EPE28381.1 - 1.5e-15 56.9 0.0 4.6e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.9 EPE28381.1 - 2.5 7.4 9.9 3.6 6.9 6.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ATP_bind_1 PF03029.12 EPE28382.1 - 2e-75 253.4 0.0 2.6e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EPE28382.1 - 2.6e-05 23.1 0.1 6.3e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 EPE28382.1 - 0.0022 18.8 2.1 0.021 15.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EPE28382.1 - 0.0029 17.0 0.0 0.007 15.8 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 EPE28382.1 - 0.005 16.7 0.0 0.017 15.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.18 EPE28382.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 EPE28382.1 - 0.072 12.1 0.9 0.099 11.7 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 EPE28382.1 - 0.088 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EPE28382.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EPE28382.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 EPE28382.1 - 0.18 10.9 0.4 0.91 8.6 0.3 2.0 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family WD40 PF00400.27 EPE28383.1 - 3.9e-21 74.0 2.6 3.5e-05 23.5 0.2 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat SNF2_N PF00176.18 EPE28384.1 - 7.1e-69 231.8 0.0 9.7e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EPE28384.1 - 1.2e-14 54.1 0.0 2.2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EPE28384.1 - 6.5e-10 38.7 0.0 1.7e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EPE28384.1 - 7.7e-10 38.4 7.4 1.7e-09 37.3 5.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE28384.1 - 6.8e-09 35.6 8.5 1.8e-08 34.2 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE28384.1 - 5.1e-07 29.2 6.2 5.1e-07 29.2 4.3 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE28384.1 - 7.4e-07 29.1 3.0 2.2e-06 27.6 2.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPE28384.1 - 1.9e-06 27.4 7.7 3.6e-06 26.5 5.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE28384.1 - 2e-06 27.3 9.9 4.1e-06 26.3 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPE28384.1 - 4.9e-05 23.1 7.3 0.0001 22.0 5.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EPE28384.1 - 0.0039 16.6 6.4 0.0095 15.4 4.2 1.9 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EPE28384.1 - 0.0053 16.6 0.1 0.12 12.3 0.0 2.9 2 0 0 2 2 2 1 U-box domain zf-Apc11 PF12861.2 EPE28384.1 - 0.0058 16.4 1.3 0.014 15.2 0.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EPE28384.1 - 0.011 15.3 5.6 0.031 13.9 3.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Arif-1 PF06770.6 EPE28384.1 - 0.37 10.1 1.5 0.88 8.9 1.0 1.6 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) zf-RING_4 PF14570.1 EPE28384.1 - 0.9 9.1 4.6 2.4 7.7 3.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HET PF06985.6 EPE28385.1 - 2.6e-34 118.3 0.1 4e-34 117.7 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MARVEL PF01284.18 EPE28386.1 - 6.4e-05 22.8 0.1 0.0001 22.1 0.1 1.4 1 0 0 1 1 1 1 Membrane-associating domain HlyIII PF03006.15 EPE28386.1 - 0.0071 15.7 1.5 0.01 15.2 1.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related CbiQ PF02361.11 EPE28386.1 - 0.0084 15.6 0.2 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Cobalt transport protein DUF3784 PF12650.2 EPE28386.1 - 0.096 12.6 3.6 0.15 12.0 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) Chromate_transp PF02417.10 EPE28386.1 - 0.14 11.7 7.4 0.24 10.9 5.1 1.3 1 0 0 1 1 1 0 Chromate transporter DUF3317 PF11779.3 EPE28386.1 - 0.36 10.3 5.9 6 6.3 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) AA_permease_2 PF13520.1 EPE28386.1 - 0.47 8.9 8.0 1.4 7.3 5.6 1.5 1 1 0 1 1 1 0 Amino acid permease DUF2973 PF11189.3 EPE28386.1 - 0.51 10.1 3.1 19 5.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2973) Fig1 PF12351.3 EPE28386.1 - 6.7 6.5 9.0 3 7.7 4.5 1.8 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Chitin_synth_1 PF01644.12 EPE28387.1 - 3.4e-84 280.5 0.1 5.1e-84 280.0 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EPE28387.1 - 2.7e-32 110.2 0.1 6.4e-32 109.0 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EPE28387.1 - 2.1e-24 85.8 2.2 1.4e-21 76.5 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EPE28387.1 - 6.1e-09 35.8 0.4 6.1e-09 35.8 0.3 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPE28387.1 - 0.00031 20.6 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CD99L2 PF12301.3 EPE28388.1 - 0.088 12.4 4.8 0.65 9.6 1.6 2.7 2 0 0 2 2 2 0 CD99 antigen like protein 2 Abhydrolase_6 PF12697.2 EPE28389.1 - 3e-07 30.5 0.1 4.9e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE28389.1 - 0.00026 20.5 0.0 0.00048 19.6 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EPE28389.1 - 0.0028 17.4 0.0 0.0067 16.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIP PF03583.9 EPE28389.1 - 0.0044 16.2 0.0 0.006 15.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_1 PF00561.15 EPE28389.1 - 0.057 12.9 0.0 0.088 12.3 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.20 EPE28390.1 - 8.4e-47 159.4 0.0 1.4e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EPE28390.1 - 4.9e-37 126.1 2.0 1.4e-11 44.5 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPE28390.1 - 2.1e-28 96.6 13.0 0.00017 21.2 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EPE28390.1 - 3.9e-28 97.2 8.0 8.1e-06 26.2 0.1 7.5 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 EPE28390.1 - 5.4e-25 87.9 0.0 8.7e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.1 EPE28390.1 - 2.1e-24 83.1 7.4 0.0031 17.6 0.0 9.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 EPE28390.1 - 1.1e-21 76.3 5.4 5.7e-07 29.5 0.0 6.2 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Kinase-like PF14531.1 EPE28390.1 - 0.062 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF1077 PF06417.7 EPE28391.1 - 2.3e-53 178.8 1.5 2.9e-53 178.4 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.15 EPE28392.1 - 6.1e-134 447.2 8.9 7.7e-134 446.8 6.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EPE28392.1 - 9.9e-17 61.3 2.2 2.9e-16 59.8 0.1 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EPE28392.1 - 2.6e-14 53.2 5.7 2e-09 37.6 0.3 4.3 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EPE28392.1 - 6.2e-10 38.3 3.2 0.011 15.7 0.0 4.9 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EPE28392.1 - 0.00013 22.3 4.2 0.8 10.2 0.0 5.4 5 1 1 6 6 6 2 HEAT-like repeat Atx10homo_assoc PF09759.4 EPE28392.1 - 0.00057 19.5 0.1 0.42 10.3 0.0 3.6 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 EPE28392.1 - 0.00067 19.0 2.5 0.44 9.8 0.1 3.2 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.18 EPE28392.1 - 0.034 13.9 2.0 4 7.4 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat T_hemolysin PF12261.3 EPE28392.1 - 0.074 12.5 0.1 0.18 11.3 0.1 1.6 2 0 0 2 2 2 0 Thermostable hemolysin FKBP_C PF00254.23 EPE28393.1 - 2.5e-28 97.9 0.1 2.9e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.16 EPE28394.1 - 3.9e-50 169.2 0.0 7.8e-32 109.9 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EPE28394.1 - 3.4e-42 143.5 0.1 1.7e-41 141.3 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EPE28394.1 - 2.7e-37 126.1 3.9 1.1e-25 88.9 0.3 2.7 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EPE28394.1 - 4.3e-25 86.8 0.9 1.2e-21 75.8 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site GST_N_2 PF13409.1 EPE28395.1 - 1e-21 76.7 0.0 2.5e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE28395.1 - 2.3e-14 53.0 0.0 1.1e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPE28395.1 - 3.9e-06 26.7 0.1 1.1e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPE28395.1 - 1.5e-05 25.1 0.0 0.057 13.6 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EPE28395.1 - 0.0015 18.9 0.0 0.0033 17.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_61 PF03443.9 EPE28396.1 - 2.2e-50 171.5 0.0 3.8e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_17 PF00332.13 EPE28397.1 - 0.00012 21.2 0.7 0.0002 20.4 0.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 EPE28397.1 - 0.0043 15.8 0.0 0.0063 15.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Radical_SAM PF04055.16 EPE28400.1 - 4.1e-24 85.6 0.7 1.2e-23 84.1 0.0 2.2 3 0 0 3 3 3 1 Radical SAM superfamily Wyosine_form PF08608.7 EPE28400.1 - 7.6e-22 77.1 0.0 1.8e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EPE28400.1 - 5.6e-09 36.1 0.2 1e-07 32.0 0.1 2.6 1 1 0 1 1 1 1 Flavodoxin FAR1 PF03101.10 EPE28401.1 - 0.00073 20.0 0.1 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain Med9 PF07544.8 EPE28401.1 - 0.0085 15.8 3.2 0.028 14.1 2.2 1.9 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 COG2 PF06148.6 EPE28401.1 - 0.23 11.3 1.4 0.54 10.1 1.0 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ApoLp-III PF07464.6 EPE28401.1 - 8.8 6.3 12.6 0.2 11.6 3.0 2.4 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF4139 PF13598.1 EPE28402.1 - 9e-57 192.7 0.6 9e-39 133.6 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EPE28402.1 - 1.6e-11 44.5 1.8 1.6e-11 44.5 1.3 4.5 3 2 1 4 4 4 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.1 EPE28402.1 - 0.00066 19.8 5.0 0.00066 19.8 3.5 2.6 2 0 0 2 2 2 1 Nucleoporin FG repeat region DUF1843 PF08898.5 EPE28402.1 - 0.047 13.7 0.5 0.24 11.4 0.4 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DUF4419 PF14388.1 EPE28403.1 - 9.6e-103 343.4 0.0 1.2e-102 343.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) FAD_binding_3 PF01494.14 EPE28404.1 - 7.6e-19 67.9 0.0 1.2e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.13 EPE28404.1 - 8.4e-12 44.5 3.2 1.4e-11 43.7 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 EPE28404.1 - 2.5e-07 29.9 0.3 0.0027 16.6 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPE28404.1 - 9.8e-06 25.8 0.4 0.00025 21.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE28404.1 - 0.07 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Epimerase PF01370.16 EPE28405.1 - 5.1e-08 32.6 0.0 9.1e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE28405.1 - 7.5e-08 31.4 0.0 2e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPE28405.1 - 1.7e-05 24.9 0.1 4.4e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPE28405.1 - 7.5e-05 21.7 0.0 0.0031 16.4 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EPE28405.1 - 0.00015 21.1 0.1 0.00059 19.1 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EPE28405.1 - 0.0024 17.7 0.1 0.028 14.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE28405.1 - 0.015 14.9 0.0 0.92 9.1 0.0 2.5 2 0 0 2 2 2 0 KR domain RmlD_sub_bind PF04321.12 EPE28405.1 - 0.095 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Acetyltransf_8 PF13523.1 EPE28405.1 - 0.13 12.1 0.1 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3425 PF11905.3 EPE28408.1 - 2.9e-29 101.7 0.5 8.9e-29 100.1 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3425) adh_short PF00106.20 EPE28409.1 - 1.5e-08 34.7 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE28409.1 - 0.0073 16.1 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MiaE_2 PF13794.1 EPE28409.1 - 0.16 11.4 0.7 4.6 6.6 0.1 2.1 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like DUF1989 PF09347.5 EPE28410.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) Neur_chan_memb PF02932.11 EPE28410.1 - 0.016 15.0 0.7 0.027 14.3 0.5 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region gag-asp_proteas PF13975.1 EPE28410.1 - 0.052 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease FAM163 PF15069.1 EPE28410.1 - 7.8 7.0 10.3 0.42 11.1 2.8 2.0 2 1 0 2 2 2 0 FAM163 family Lipase_GDSL_2 PF13472.1 EPE28412.1 - 9.1e-19 68.2 0.0 1.2e-18 67.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE28412.1 - 7.6e-17 61.9 0.0 9.1e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Methyltransf_11 PF08241.7 EPE28413.1 - 2.2e-13 50.4 0.0 5.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE28413.1 - 3.3e-11 42.7 0.0 1.8e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EPE28413.1 - 4.5e-11 42.5 0.0 1.5e-10 40.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE28413.1 - 3.1e-09 37.0 0.0 6.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE28413.1 - 4.1e-08 33.5 0.0 9.4e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE28413.1 - 6.1e-08 32.5 0.0 1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE28413.1 - 4.5e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPE28413.1 - 4.5e-06 26.1 0.0 7.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EPE28413.1 - 1.5e-05 25.5 0.0 4.1e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EPE28413.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_PK PF05891.7 EPE28413.1 - 0.022 14.0 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase UPF0020 PF01170.13 EPE28413.1 - 0.029 13.9 0.1 0.058 12.9 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 NUC153 PF08159.7 EPE28414.1 - 6.5e-09 35.2 10.8 6.9e-09 35.1 0.0 3.3 3 0 0 3 3 3 2 NUC153 domain EamA PF00892.15 EPE28415.1 - 1.2e-19 70.5 30.1 8.2e-14 51.7 3.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EPE28415.1 - 6.4e-05 23.1 6.7 6.4e-05 23.1 4.7 3.8 2 1 0 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EPE28415.1 - 0.021 13.9 5.1 0.069 12.2 3.5 2.0 1 1 0 1 1 1 0 Nucleotide-sugar transporter DUF2420 PF10336.4 EPE28416.1 - 0.0029 17.1 0.1 0.0064 16.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) IBN_N PF03810.14 EPE28416.1 - 0.0037 17.1 0.0 0.0086 15.9 0.0 1.6 1 1 0 1 1 1 1 Importin-beta N-terminal domain DUF4477 PF14780.1 EPE28416.1 - 0.053 12.8 0.2 0.083 12.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4477) HET PF06985.6 EPE28418.1 - 4.1e-08 33.4 0.0 6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.19 EPE28423.1 - 1e-39 135.3 28.0 4.5e-20 71.6 7.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4131 PF13567.1 EPE28423.1 - 0.89 8.9 8.1 0.45 9.8 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) SNF2_N PF00176.18 EPE28424.1 - 1.6e-63 214.3 0.1 1.6e-63 214.3 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 EPE28424.1 - 1.6e-07 30.8 7.2 3.4e-07 29.8 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 EPE28424.1 - 5.8e-07 29.2 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EPE28424.1 - 1.6e-06 28.0 6.8 3.2e-06 27.0 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE28424.1 - 1.3e-05 24.7 5.2 2.6e-05 23.7 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPE28424.1 - 1.9e-05 24.4 6.7 4e-05 23.4 4.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EPE28424.1 - 3.6e-05 23.5 7.3 7e-05 22.5 5.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPE28424.1 - 4.1e-05 23.2 7.8 8e-05 22.2 5.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPE28424.1 - 0.0058 16.3 1.2 0.016 14.9 0.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger FYVE PF01363.16 EPE28424.1 - 0.049 13.5 3.6 0.14 12.0 2.5 1.8 1 0 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.3 EPE28424.1 - 0.12 11.9 4.2 0.3 10.6 2.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit NARP1 PF12569.3 EPE28424.1 - 0.19 10.4 15.1 0.34 9.6 8.2 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Tom37_C PF11801.3 EPE28424.1 - 2.1 8.1 9.3 13 5.6 5.0 2.7 2 0 0 2 2 2 0 Tom37 C-terminal domain Peptidase_M24 PF00557.19 EPE28425.1 - 5.6e-10 39.1 0.0 6.2e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Ank_2 PF12796.2 EPE28427.1 - 1.8e-37 127.5 1.0 9e-21 74.0 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE28427.1 - 1.6e-20 71.8 0.3 4.1e-09 35.8 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EPE28427.1 - 3.3e-16 57.7 0.0 5.7e-06 26.0 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EPE28427.1 - 4.6e-16 58.8 0.3 2e-09 37.7 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE28427.1 - 3.1e-15 55.8 0.1 3e-13 49.5 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) ATP-grasp_4 PF13535.1 EPE28428.1 - 3e-20 72.7 0.0 2.7e-19 69.6 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EPE28428.1 - 1.3e-06 27.9 0.0 2.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EPE28428.1 - 0.0052 15.5 0.0 0.035 12.8 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.6 EPE28428.1 - 0.0054 16.2 0.0 0.0098 15.3 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.12 EPE28428.1 - 0.18 11.0 0.0 0.38 10.0 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Cys_Met_Meta_PP PF01053.15 EPE28429.1 - 1.5e-45 155.1 0.0 1.7e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Cys_Met_Meta_PP PF01053.15 EPE28430.1 - 7.2e-17 60.7 0.0 9e-17 60.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NAS PF03059.11 EPE28431.1 - 2e-30 105.9 0.0 2.5e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.1 EPE28431.1 - 0.00061 19.4 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE28431.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EPE28431.1 - 0.047 14.2 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy PF03171.15 EPE28432.1 - 2.5e-17 62.9 0.0 4e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EPE28432.1 - 4e-08 33.8 0.0 7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DAO PF01266.19 EPE28433.1 - 2.8e-49 167.9 0.0 3.3e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPE28433.1 - 0.00042 18.9 0.0 0.17 10.3 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 EPE28433.1 - 0.00044 20.0 0.7 0.015 15.0 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPE28433.1 - 0.00045 20.3 0.0 0.036 14.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE28433.1 - 0.00066 19.6 0.1 0.0016 18.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE28433.1 - 0.0015 17.5 0.0 0.018 13.9 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPE28433.1 - 0.0073 16.2 0.0 0.061 13.1 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EPE28433.1 - 0.01 14.9 0.0 2 7.4 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 EPE28433.1 - 0.04 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EPE28433.1 - 0.074 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EPE28433.1 - 0.078 12.0 0.1 0.44 9.5 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPE28433.1 - 0.088 13.2 0.0 2.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PALP PF00291.20 EPE28433.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Cys_Met_Meta_PP PF01053.15 EPE28434.1 - 3.9e-113 377.6 0.0 4.5e-113 377.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EPE28434.1 - 2.4e-07 29.8 0.0 4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPE28434.1 - 3.8e-05 22.9 0.0 5.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 EPE28434.1 - 0.0019 16.9 0.0 0.0027 16.4 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EPE28434.1 - 0.055 11.7 0.0 0.082 11.1 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase AMP-binding PF00501.23 EPE28435.1 - 1.1e-164 547.7 0.0 6.1e-82 275.2 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EPE28435.1 - 5.1e-95 317.7 0.0 1.2e-32 113.0 0.1 4.4 3 1 0 3 3 3 3 Condensation domain AMP-binding_C PF13193.1 EPE28435.1 - 1.8e-15 57.5 0.0 1.4e-08 35.5 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EPE28435.1 - 1.5e-13 50.8 0.1 9.2e-07 29.0 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site P5CR_dimer PF14748.1 EPE28435.1 - 8.4e-12 45.0 0.4 2.7e-11 43.4 0.3 1.9 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EPE28435.1 - 7.5e-07 29.5 0.0 2.3e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent LAGLIDADG_2 PF03161.8 EPE28435.1 - 0.48 10.2 0.0 1.1 9.1 0.0 1.5 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family 2OG-FeII_Oxy PF03171.15 EPE28436.1 - 6.5e-16 58.4 0.0 1.1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EPE28436.1 - 1.2e-05 25.8 0.0 2.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Abhydrolase_1 PF00561.15 EPE28437.1 - 9.3e-33 113.6 0.1 4.1e-31 108.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE28437.1 - 6.8e-18 65.3 0.0 1.3e-17 64.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE28437.1 - 0.00081 19.1 0.0 0.011 15.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EPE28437.1 - 0.072 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DIOX_N PF14226.1 EPE28438.1 - 3.3e-19 69.5 0.0 9.5e-19 68.0 0.0 1.8 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPE28438.1 - 2.3e-13 50.2 0.0 1.4e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 EPE28439.1 - 7.3e-85 284.8 0.1 9.7e-85 284.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme HxxPF_rpt PF13745.1 EPE28439.1 - 9.1e-13 48.3 0.3 2.8e-12 46.7 0.2 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain AMP-binding_C PF13193.1 EPE28439.1 - 3.1e-11 44.0 0.0 1.2e-10 42.1 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EPE28440.1 - 1.3e-79 267.6 0.0 1.8e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EPE28440.1 - 1.4e-61 208.0 2.0 2.1e-61 207.3 1.4 1.2 1 0 0 1 1 1 1 Condensation domain HxxPF_rpt PF13745.1 EPE28440.1 - 9.7e-24 83.5 0.2 3.2e-23 81.8 0.0 2.0 2 0 0 2 2 2 1 HxxPF-repeated domain AMP-binding_C PF13193.1 EPE28440.1 - 1.3e-12 48.4 0.0 3.2e-11 44.0 0.0 3.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EPE28440.1 - 1.5e-10 41.1 0.2 7.7e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thioesterase PF00975.15 EPE28441.1 - 1.6e-11 44.9 0.0 2.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EPE28441.1 - 1e-05 25.5 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE28441.1 - 0.07 12.8 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family OxoDH_E1alpha_N PF12573.3 EPE28441.1 - 0.14 11.7 1.2 0.32 10.5 0.9 1.5 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal MFS_1 PF07690.11 EPE28442.1 - 3.3e-24 85.2 25.6 3.3e-24 85.2 17.7 1.7 3 0 0 3 3 3 1 Major Facilitator Superfamily DUF2721 PF11026.3 EPE28442.1 - 0.014 15.0 1.7 0.014 15.0 1.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Prominin PF05478.6 EPE28442.1 - 0.094 10.2 0.7 0.13 9.7 0.5 1.1 1 0 0 1 1 1 0 Prominin DUF973 PF06157.6 EPE28442.1 - 0.11 11.4 7.2 0.2 10.5 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF973) MFS_1 PF07690.11 EPE28443.1 - 3.3e-33 114.8 15.5 3.3e-33 114.8 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 EPE28444.1 - 4.5e-23 81.2 1.0 4.5e-23 81.2 0.7 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPE28444.1 - 0.027 14.3 0.0 0.084 12.7 0.0 1.9 1 0 0 1 1 1 0 Berberine and berberine like Glyco_hydro_43 PF04616.9 EPE28445.1 - 3.7e-38 131.2 3.7 6.2e-38 130.5 2.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Esterase_phd PF10503.4 EPE28446.1 - 2.2e-18 66.3 0.6 3.6e-18 65.6 0.4 1.3 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EPE28446.1 - 4.8e-12 45.5 2.0 7e-12 45.0 1.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE28446.1 - 9.4e-06 25.4 0.2 1.5e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE28446.1 - 1.5e-05 25.0 0.1 2.4e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 EPE28446.1 - 0.0065 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Serine carboxypeptidase COesterase PF00135.23 EPE28446.1 - 0.0077 14.9 0.1 0.014 14.1 0.1 1.4 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.15 EPE28446.1 - 0.016 14.7 0.6 0.025 14.1 0.4 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EPE28446.1 - 0.045 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_L28 PF00830.14 EPE28448.1 - 6.1e-19 67.6 1.2 9.4e-19 67.0 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L28 family ATP_bind_4 PF01902.12 EPE28448.1 - 0.075 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 ATP-binding region MFS_1 PF07690.11 EPE28449.1 - 8.1e-42 143.1 59.3 4.1e-40 137.5 30.4 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE28449.1 - 3.1e-09 35.9 15.6 3.1e-09 35.9 10.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter GATase PF00117.23 EPE28450.1 - 1.6e-12 47.3 0.0 2.8e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPE28450.1 - 0.1 11.9 0.4 0.64 9.4 0.3 2.2 1 1 0 1 1 1 0 Peptidase C26 S1-P1_nuclease PF02265.11 EPE28451.1 - 5.6e-66 222.7 0.0 6.9e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Oligomerisation PF02410.10 EPE28452.1 - 4.7e-07 29.7 0.2 0.045 13.7 0.1 3.2 3 0 0 3 3 3 2 Oligomerisation domain TPR_14 PF13428.1 EPE28452.1 - 0.005 17.3 3.8 0.058 14.0 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPE28452.1 - 0.021 15.5 0.1 0.11 13.2 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPE28452.1 - 0.069 13.0 0.7 0.29 11.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPE28452.1 - 0.11 12.3 0.9 0.49 10.2 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPE28452.1 - 0.19 11.3 0.1 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Amidase PF01425.16 EPE28453.1 - 1.6e-86 290.8 0.1 2.1e-86 290.5 0.1 1.2 1 0 0 1 1 1 1 Amidase DUF612 PF04747.7 EPE28456.1 - 0.031 13.1 1.8 0.045 12.6 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF612 PBD PF00786.23 EPE28456.1 - 0.07 13.5 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 P21-Rho-binding domain DUF4140 PF13600.1 EPE28456.1 - 0.075 13.4 2.1 0.16 12.4 1.5 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 EPE28456.1 - 0.2 11.5 5.9 0.47 10.2 4.1 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CCDC-167 PF15188.1 EPE28456.1 - 1.7 8.6 5.8 1.3 9.0 2.7 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Angiomotin_C PF12240.3 EPE28456.1 - 6.3 6.2 12.7 0.79 9.1 5.6 1.8 2 0 0 2 2 2 0 Angiomotin C terminal DUF972 PF06156.8 EPE28458.1 - 0.011 16.0 5.5 0.018 15.3 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CENP-H PF05837.7 EPE28458.1 - 0.056 13.6 7.5 0.091 12.9 5.2 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF904 PF06005.7 EPE28458.1 - 0.084 13.1 6.9 0.16 12.2 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) BTV_NS2 PF04514.7 EPE28458.1 - 0.097 11.5 3.5 0.16 10.8 2.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 IncA PF04156.9 EPE28458.1 - 0.11 12.1 5.6 0.15 11.6 3.9 1.2 1 0 0 1 1 1 0 IncA protein Foamy_virus_ENV PF03408.9 EPE28458.1 - 0.12 9.9 3.0 0.15 9.5 2.1 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein V_ATPase_I PF01496.14 EPE28458.1 - 0.2 9.4 2.0 0.27 9.0 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.3 EPE28458.1 - 0.68 8.5 5.2 0.92 8.0 3.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Sec20 PF03908.8 EPE28458.1 - 1.4 8.6 4.9 2.6 7.8 3.4 1.4 1 0 0 1 1 1 0 Sec20 Fungal_trans PF04082.13 EPE28461.1 - 1.2e-24 86.5 0.0 2.2e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE28461.1 - 3.4e-06 26.8 15.4 6e-06 26.0 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiF PF00899.16 EPE28463.1 - 0.00074 19.3 0.2 0.0073 16.1 0.1 2.3 1 1 1 2 2 2 1 ThiF family Rib_5-P_isom_A PF06026.9 EPE28464.1 - 7.5e-40 136.0 0.0 6.3e-33 113.5 0.0 3.1 2 1 1 3 3 3 3 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EPE28464.1 - 0.02 14.5 0.1 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain ECH PF00378.15 EPE28465.1 - 9e-45 152.7 0.0 1.2e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3005 PF11448.3 EPE28465.1 - 0.12 12.0 0.2 15 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) ECH PF00378.15 EPE28466.1 - 2.6e-45 154.4 0.1 3.3e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EPE28466.1 - 0.0016 18.1 0.3 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 RVT_1 PF00078.22 EPE28468.1 - 3e-07 30.0 0.0 1.4e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATP-synt_E_2 PF08112.6 EPE28468.1 - 0.0039 17.2 0.4 0.064 13.3 0.1 2.6 2 0 0 2 2 2 1 ATP synthase epsilon subunit Nfu_N PF08712.6 EPE28468.1 - 0.014 15.0 0.3 0.2 11.2 0.1 2.6 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal PBP1_TM PF14812.1 EPE28468.1 - 0.092 13.0 0.5 0.26 11.6 0.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal p450 PF00067.17 EPE28469.1 - 2.3e-15 56.1 0.1 3.7e-13 48.8 0.0 3.3 2 2 0 2 2 2 2 Cytochrome P450 HsbA PF12296.3 EPE28470.1 - 2.8e-15 56.2 2.5 2.8e-15 56.2 1.1 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF2756 PF10956.3 EPE28470.1 - 0.15 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) DUF31 PF01732.11 EPE28470.1 - 0.33 10.2 2.1 0.41 9.9 1.4 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) NPV_P10 PF05531.7 EPE28470.1 - 3.4 7.9 6.1 7.2 6.9 0.9 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CTP_transf_1 PF01148.15 EPE28471.1 - 1.1e-80 270.9 31.8 1.5e-80 270.6 22.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Asp PF00026.18 EPE28471.1 - 0.00014 21.2 0.0 0.025 13.8 0.0 3.3 4 1 0 4 4 4 2 Eukaryotic aspartyl protease DUF3636 PF12331.3 EPE28472.1 - 3.5e-45 153.2 0.6 7.2e-45 152.2 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) rRNA_processing PF08524.6 EPE28476.1 - 0.013 15.2 7.1 0.016 15.0 4.9 1.1 1 0 0 1 1 1 0 rRNA processing DUF3580 PF12117.3 EPE28476.1 - 0.039 13.8 0.1 0.052 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) DUF4337 PF14235.1 EPE28476.1 - 0.32 10.8 1.6 0.33 10.7 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Myb_Cef PF11831.3 EPE28476.1 - 0.68 9.1 6.7 0.78 8.9 4.7 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component DUF4355 PF14265.1 EPE28476.1 - 1.4 8.8 12.7 1.7 8.6 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Nop14 PF04147.7 EPE28476.1 - 1.8 6.3 8.3 2 6.1 5.7 1.0 1 0 0 1 1 1 0 Nop14-like family zf-RING_2 PF13639.1 EPE28477.1 - 4.9e-05 23.0 10.9 4.9e-05 23.0 7.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPE28477.1 - 7.9e-05 22.2 6.7 0.0002 20.9 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE28477.1 - 0.00037 20.4 11.0 0.00037 20.4 7.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 EPE28477.1 - 0.0022 17.7 1.9 0.0045 16.7 1.3 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.1 EPE28477.1 - 0.014 15.0 8.6 0.014 15.0 6.0 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE28477.1 - 0.022 14.4 9.9 0.022 14.4 6.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EPE28477.1 - 0.059 12.9 7.8 0.16 11.5 5.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EPE28477.1 - 0.29 10.8 6.5 0.8 9.4 4.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger E1-E2_ATPase PF00122.15 EPE28479.1 - 1.1e-20 73.6 0.1 4e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPE28479.1 - 1.6e-20 74.4 0.0 1.1e-19 71.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPE28479.1 - 2e-17 64.0 0.0 4.9e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPE28479.1 - 4.4e-06 26.5 0.0 0.00013 21.8 0.0 2.5 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPE28479.1 - 0.026 14.1 1.3 0.071 12.6 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4059 PF13268.1 EPE28479.1 - 0.069 13.3 0.5 8.5 6.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) PLDc PF00614.17 EPE28480.1 - 2.1e-12 46.3 4.3 1.1e-06 28.1 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EPE28480.1 - 6.1e-12 45.3 0.0 1.2e-05 25.0 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain NB PF04159.8 EPE28481.1 - 0.16 11.7 0.1 12 5.6 0.0 2.2 1 1 1 2 2 2 0 NB glycoprotein PKD_channel PF08016.7 EPE28483.1 - 4.9e-07 28.5 19.9 4.4e-05 22.0 13.8 2.2 1 1 0 1 1 1 1 Polycystin cation channel DUF843 PF05814.6 EPE28483.1 - 4.5 7.1 10.3 5.6 6.8 0.5 3.2 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) peroxidase PF00141.18 EPE28484.1 - 7.5e-16 58.3 0.0 1.3e-15 57.5 0.0 1.4 1 1 0 1 1 1 1 Peroxidase GMC_oxred_N PF00732.14 EPE28486.1 - 2.2e-66 224.0 0.0 3.6e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE28486.1 - 1.3e-39 135.7 0.1 2.1e-39 135.1 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EPE28486.1 - 5.9e-05 23.0 0.1 0.00021 21.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE28486.1 - 0.00019 20.4 0.1 0.00048 19.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EPE28486.1 - 0.0059 15.5 2.3 0.017 14.0 1.6 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 EPE28486.1 - 0.0092 15.9 0.1 0.049 13.6 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.7 EPE28486.1 - 0.012 14.5 0.1 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EPE28486.1 - 0.015 13.8 0.0 0.027 12.9 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EPE28486.1 - 0.038 13.8 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DNA_repr_REX1B PF14966.1 EPE28487.1 - 0.029 14.7 0.9 2.5 8.5 0.0 3.3 2 1 1 3 3 3 0 DNA repair REX1-B THOC7 PF05615.8 EPE28487.1 - 2.6 8.3 7.0 2.1 8.6 0.6 2.9 4 0 0 4 4 4 0 Tho complex subunit 7 MAPEG PF01124.13 EPE28489.1 - 1.7e-15 56.7 0.5 2.1e-15 56.4 0.4 1.2 1 0 0 1 1 1 1 MAPEG family BTP PF05232.7 EPE28489.1 - 0.25 11.1 0.1 0.25 11.1 0.1 2.0 3 0 0 3 3 3 0 Bacterial Transmembrane Pair family GLTP PF08718.6 EPE28491.1 - 3.6e-45 153.6 0.0 4.6e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Abhydrolase_1 PF00561.15 EPE28493.1 - 1.7e-14 53.9 0.6 2.3e-07 30.6 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EPE28493.1 - 4.5e-14 52.1 0.0 9.9e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EPE28493.1 - 3.8e-06 26.9 0.1 2.7e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE28493.1 - 0.0099 15.6 0.0 0.17 11.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_10 PF05971.7 EPE28494.1 - 2.1e-64 217.5 0.0 3e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) PrmA PF06325.8 EPE28494.1 - 8.5e-08 31.6 0.0 1.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EPE28494.1 - 2.7e-05 23.6 0.0 0.00011 21.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EPE28494.1 - 4.6e-05 23.4 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE28494.1 - 8.2e-05 22.2 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE28494.1 - 0.00022 21.7 0.0 0.0007 20.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 EPE28494.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 EPE28494.1 - 0.017 15.5 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EPE28494.1 - 0.04 14.2 0.0 3.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Macro PF01661.16 EPE28495.1 - 2.1e-39 134.1 0.1 3.1e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Macro domain tRNA-synt_1c PF00749.16 EPE28496.1 - 1.1e-99 333.1 0.0 1.5e-99 332.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EPE28496.1 - 1.3e-28 99.8 0.1 4e-28 98.2 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_S17e PF00833.13 EPE28497.1 - 1.2e-59 199.4 0.5 1.5e-59 199.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EPE28497.1 - 0.025 15.2 0.1 0.034 14.8 0.1 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal RPAP2_Rtr1 PF04181.8 EPE28498.1 - 2.7e-18 65.8 0.0 5.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_9 PF14604.1 EPE28499.1 - 1.8e-10 40.2 0.2 6.3e-10 38.4 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EPE28499.1 - 1.5e-09 37.0 0.1 3.8e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPE28499.1 - 8.7e-09 34.7 0.0 1.7e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TFIIA PF03153.8 EPE28499.1 - 0.001 19.0 17.0 0.001 19.0 11.8 3.4 2 1 2 4 4 4 1 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.8 EPE28499.1 - 3.3 7.2 20.6 1.1 8.7 7.2 2.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Acetyltransf_1 PF00583.19 EPE28500.1 - 8.1e-05 22.5 0.1 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.3 EPE28500.1 - 0.00021 20.3 0.3 0.0003 19.8 0.2 1.2 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Acetyltransf_CG PF14542.1 EPE28500.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Amidase PF01425.16 EPE28501.1 - 2.7e-109 365.9 0.0 3.7e-109 365.5 0.0 1.2 1 0 0 1 1 1 1 Amidase Fip1 PF05182.8 EPE28504.1 - 8.9e-21 72.8 0.9 1.8e-20 71.9 0.6 1.5 1 0 0 1 1 1 1 Fip1 motif Daxx PF03344.10 EPE28504.1 - 2.3 6.6 13.1 3 6.2 9.1 1.2 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 EPE28504.1 - 2.8 7.4 12.3 4.7 6.7 8.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region M_domain PF12938.2 EPE28504.1 - 7.6 6.2 15.0 13 5.4 10.4 1.4 1 0 0 1 1 1 0 M domain of GW182 Nucleoporin_FG PF13634.1 EPE28505.1 - 1.1e-33 115.8 151.7 1.1e-16 61.0 32.7 4.5 2 1 3 5 5 5 4 Nucleoporin FG repeat region Cupin_8 PF13621.1 EPE28505.1 - 0.035 13.5 0.0 0.062 12.7 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain DUF2025 PF09634.5 EPE28506.1 - 0.16 11.7 0.6 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2025) WD40 PF00400.27 EPE28507.1 - 2.1e-06 27.4 11.7 0.039 13.8 0.3 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat DAO PF01266.19 EPE28508.1 - 1.2e-29 103.3 0.1 1.5e-29 103.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE28508.1 - 0.00074 19.5 1.5 0.0012 18.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE28508.1 - 0.0068 15.2 0.0 0.0099 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EPE28508.1 - 0.012 14.7 0.1 0.012 14.7 0.0 2.0 2 1 1 3 3 3 0 Thi4 family Pyr_redox_2 PF07992.9 EPE28508.1 - 0.032 14.1 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1188 PF06690.6 EPE28508.1 - 0.085 11.9 0.0 1.7 7.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) FAD_binding_3 PF01494.14 EPE28508.1 - 0.11 11.4 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Toxin_28 PF08115.6 EPE28508.1 - 0.16 11.6 0.2 0.53 9.9 0.2 1.9 1 0 0 1 1 1 0 SFI toxin family 3Beta_HSD PF01073.14 EPE28509.1 - 1.7e-43 148.3 0.0 2.2e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE28509.1 - 1e-22 80.7 0.0 1.4e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE28509.1 - 1.4e-11 44.7 0.0 2.3e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPE28509.1 - 1.2e-10 41.5 0.4 3.3e-10 40.1 0.1 1.9 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EPE28509.1 - 1.3e-10 40.6 0.1 4.4e-05 22.5 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EPE28509.1 - 4.1e-07 29.1 0.0 6.8e-07 28.4 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EPE28509.1 - 6e-07 28.6 0.0 4e-05 22.6 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EPE28509.1 - 1.6e-05 24.6 0.1 4.8e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 KR domain DapB_N PF01113.15 EPE28509.1 - 0.0049 16.7 0.0 0.0084 16.0 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EPE28509.1 - 0.05 12.5 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pyr_redox_2 PF07992.9 EPE28510.1 - 1.5e-18 67.3 3.9 8.1e-12 45.4 0.1 3.5 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE28510.1 - 8.3e-17 61.3 3.3 1.6e-15 57.2 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EPE28510.1 - 7.5e-16 58.1 0.0 2.9e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain XdhC_C PF13478.1 EPE28510.1 - 3.2e-06 27.4 0.0 0.0045 17.3 0.0 3.5 3 1 0 3 3 2 1 XdhC Rossmann domain HI0933_like PF03486.9 EPE28510.1 - 5.3e-06 25.1 5.9 0.053 11.9 0.0 3.2 2 1 1 3 3 3 3 HI0933-like protein NAD_binding_7 PF13241.1 EPE28510.1 - 3.1e-05 24.1 3.0 0.13 12.5 0.0 2.7 3 0 0 3 3 3 2 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 EPE28510.1 - 9.8e-05 22.5 0.3 0.27 11.2 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE28510.1 - 0.0002 20.3 3.1 0.29 9.9 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 EPE28510.1 - 0.00023 20.1 6.2 0.25 10.2 0.4 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EPE28510.1 - 0.0003 20.5 1.3 0.00096 18.8 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EPE28510.1 - 0.0027 16.6 8.5 0.15 10.8 0.6 3.1 3 2 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.12 EPE28510.1 - 0.0041 16.2 0.9 0.047 12.7 0.0 2.3 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 EPE28510.1 - 0.012 15.0 4.2 0.14 11.5 0.0 2.7 3 0 0 3 3 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EPE28510.1 - 0.02 14.0 0.3 0.05 12.7 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EPE28510.1 - 0.076 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EPE28510.1 - 0.13 12.2 0.9 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.14 EPE28510.1 - 0.49 9.3 2.1 7.3 5.5 0.1 2.4 2 1 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 EPE28510.1 - 0.54 9.0 8.0 0.89 8.3 0.2 3.7 4 0 0 4 4 4 0 FAD binding domain NAD_binding_8 PF13450.1 EPE28510.1 - 0.8 9.7 5.5 4.7 7.3 0.2 2.8 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain Ald_Xan_dh_C2 PF02738.13 EPE28511.1 - 7.2e-193 641.8 0.3 9.7e-193 641.3 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EPE28511.1 - 3.2e-50 169.8 0.0 5.7e-50 169.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EPE28511.1 - 5.7e-33 112.9 0.1 2.9e-32 110.6 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EPE28511.1 - 9.2e-30 102.9 0.0 2.2e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EPE28511.1 - 2.5e-28 97.7 0.0 5.3e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EPE28511.1 - 5.5e-08 32.4 0.1 5.5e-08 32.4 0.1 2.7 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r3 PF04539.11 EPE28511.1 - 0.14 12.0 0.2 0.8 9.6 0.1 2.2 2 0 0 2 2 2 0 Sigma-70 region 3 p450 PF00067.17 EPE28512.1 - 1.8e-24 86.1 0.0 1.3e-21 76.7 0.0 2.9 1 1 0 2 2 2 2 Cytochrome P450 Amino_oxidase PF01593.19 EPE28513.1 - 8.7e-14 51.4 0.1 6.7e-12 45.2 0.0 2.7 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPE28513.1 - 7.6e-12 45.0 0.1 1.6e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPE28513.1 - 2.8e-07 30.8 0.1 0.0027 17.8 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE28513.1 - 9e-06 24.8 0.0 0.00054 18.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPE28513.1 - 1.5e-05 24.8 0.1 0.034 13.9 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPE28513.1 - 0.00065 19.6 0.1 0.032 14.1 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EPE28513.1 - 0.00082 18.9 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EPE28513.1 - 0.003 16.1 0.0 1.4 7.3 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.22 EPE28513.1 - 0.0086 16.4 0.1 0.16 12.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE28513.1 - 0.088 11.6 0.1 0.21 10.4 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain V-SNARE PF05008.10 EPE28514.1 - 1.5e-21 76.2 2.3 1.5e-21 76.2 1.6 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EPE28514.1 - 1.3e-15 57.1 0.3 1.3e-15 57.1 0.2 2.6 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus TBCA PF02970.11 EPE28514.1 - 0.012 15.6 3.3 1.9 8.5 0.1 2.9 2 1 1 3 3 3 0 Tubulin binding cofactor A YqjK PF13997.1 EPE28514.1 - 0.02 15.0 1.0 0.34 11.1 0.1 2.4 2 0 0 2 2 2 0 YqjK-like protein MbeB_N PF04837.7 EPE28514.1 - 0.1 12.6 3.8 1.4 9.0 0.0 3.4 4 0 0 4 4 4 0 MbeB-like, N-term conserved region DUF1542 PF07564.6 EPE28514.1 - 0.11 12.5 1.0 0.19 11.7 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Spectrin PF00435.16 EPE28514.1 - 0.19 12.0 2.8 0.27 11.5 0.3 2.4 1 1 2 3 3 3 0 Spectrin repeat Tropomyosin_1 PF12718.2 EPE28514.1 - 0.22 11.3 4.5 0.58 9.9 2.3 2.0 1 1 0 1 1 1 0 Tropomyosin like Methyltransf_23 PF13489.1 EPE28515.1 - 1.2e-23 83.5 0.0 2.2e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE28515.1 - 1.7e-08 34.7 0.0 1.4e-07 31.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE28515.1 - 1.2e-07 32.3 0.0 2e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE28515.1 - 2.4e-07 30.4 0.0 7.2e-06 25.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE28515.1 - 2.6e-06 27.8 0.0 6.5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE28515.1 - 0.00068 19.0 0.0 0.055 12.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EPE28515.1 - 0.00073 19.8 0.0 0.0031 17.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPE28515.1 - 0.0018 17.3 0.1 0.018 14.0 0.0 2.5 4 0 0 4 4 4 1 Putative methyltransferase Methyltransf_26 PF13659.1 EPE28515.1 - 0.004 17.1 0.0 0.0089 16.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EPE28515.1 - 0.0052 16.8 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EPE28515.1 - 0.014 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EPE28515.1 - 0.019 14.0 0.0 0.087 11.9 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family UPF0258 PF06789.7 EPE28515.1 - 0.042 13.9 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Methyltransf_16 PF10294.4 EPE28515.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF2407_C PF13373.1 EPE28516.1 - 1.9e-35 121.7 0.2 2.7e-35 121.3 0.1 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EPE28516.1 - 2e-27 95.1 0.0 3.9e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EPE28516.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Aminotran_1_2 PF00155.16 EPE28517.1 - 8.1e-60 202.6 0.0 2.2e-59 201.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPE28517.1 - 0.022 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EPE28517.1 - 0.041 12.1 0.0 0.061 11.5 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Rhodanese PF00581.15 EPE28518.1 - 5.1e-05 23.5 0.0 0.00013 22.3 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Fungal_trans PF04082.13 EPE28519.1 - 3.1e-07 29.5 0.1 8.2e-07 28.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Utp12 PF04003.7 EPE28521.1 - 7e-22 77.4 0.1 9.8e-22 76.9 0.1 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Utp14 PF04615.8 EPE28521.1 - 0.81 7.7 23.5 1.3 7.1 1.4 2.1 2 0 0 2 2 2 0 Utp14 protein BUD22 PF09073.5 EPE28521.1 - 7.9 5.4 37.5 0.85 8.6 14.8 2.1 2 0 0 2 2 2 0 BUD22 Bromodomain PF00439.20 EPE28522.1 - 2.9e-36 123.2 0.2 6.4e-20 70.8 0.0 2.5 2 0 0 2 2 2 2 Bromodomain HAD_2 PF13419.1 EPE28523.1 - 4.2e-17 62.9 0.0 5.7e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPE28523.1 - 1.9e-09 38.2 0.0 9.3e-08 32.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE28523.1 - 1.1e-05 24.9 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EPE28523.1 - 0.00085 19.1 0.0 0.029 14.2 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EPE28523.1 - 0.029 14.5 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Dabb PF07876.7 EPE28524.1 - 5.8e-24 84.3 0.0 6.4e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fe-S_biosyn PF01521.15 EPE28525.1 - 5.3e-19 68.2 0.0 7.6e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1741 PF08427.5 EPE28526.1 - 5.7e-82 274.7 0.1 1.9e-81 273.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) adh_short PF00106.20 EPE28528.1 - 9e-14 51.7 0.1 1.5e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE28528.1 - 8.8e-06 25.4 0.1 2.1e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 KR domain NUC173 PF08161.7 EPE28529.1 - 9.2e-77 256.8 0.2 4e-73 245.0 0.0 3.4 3 0 0 3 3 3 2 NUC173 domain HEAT_2 PF13646.1 EPE28529.1 - 0.00038 20.6 4.8 0.56 10.5 0.2 4.9 4 0 0 4 4 4 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EPE28529.1 - 0.019 15.3 0.0 1.5e+02 2.8 0.0 4.6 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EPE28529.1 - 0.031 14.3 0.2 8.7 6.7 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat DUF4646 PF15496.1 EPE28530.1 - 1.6e-07 31.4 0.0 3.1e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) HAUS4 PF14735.1 EPE28531.1 - 0.00053 19.3 5.4 0.00093 18.5 3.7 1.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 YgaB PF14182.1 EPE28531.1 - 0.1 12.8 1.9 0.16 12.2 0.1 2.2 3 0 0 3 3 3 0 YgaB-like protein Aminotran_1_2 PF00155.16 EPE28532.1 - 8.9e-90 301.2 0.0 1e-89 301.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AAA_17 PF13207.1 EPE28533.1 - 2.7e-06 28.2 0.0 9.3e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPE28533.1 - 3.1e-05 24.2 0.0 7.9e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 EPE28533.1 - 0.00022 20.8 0.0 0.0005 19.7 0.0 1.7 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.13 EPE28533.1 - 0.0062 16.1 0.0 0.025 14.1 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 EPE28533.1 - 0.021 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPE28533.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain zinc-ribbons_6 PF07191.7 EPE28534.1 - 0.11 12.2 6.1 0.41 10.4 0.7 3.0 3 1 0 3 3 3 0 zinc-ribbons zf-FCS PF06467.9 EPE28534.1 - 0.57 9.8 8.5 0.9 9.2 0.9 3.2 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif C1_1 PF00130.17 EPE28534.1 - 1.4 8.7 9.0 1e+02 2.7 3.9 3.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 EPE28534.1 - 1.8 8.4 7.3 21 5.0 5.0 2.5 1 1 0 1 1 1 0 Double zinc ribbon G8 PF10162.4 EPE28535.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 G8 domain Pacs-1 PF10254.4 EPE28535.1 - 0.15 10.6 0.7 0.17 10.5 0.5 1.0 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein DUF917 PF06032.7 EPE28536.1 - 9.2e-111 369.7 0.6 1.6e-110 369.0 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EPE28536.1 - 7.8e-47 159.7 2.9 7.8e-47 159.7 2.0 3.3 3 1 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EPE28536.1 - 1.1e-32 112.9 0.1 4.2e-30 104.5 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 EPE28536.1 - 0.00022 20.6 6.6 0.0092 15.3 0.0 3.2 3 1 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.1 EPE28536.1 - 0.0026 16.1 3.4 0.014 13.7 0.0 2.6 3 0 0 3 3 3 1 MutL protein StbA PF06406.6 EPE28536.1 - 0.0043 16.0 0.4 0.53 9.1 0.0 2.8 2 1 1 3 3 3 1 StbA protein tRNA_U5-meth_tr PF05958.6 EPE28536.1 - 0.3 9.7 0.0 0.55 8.8 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase adh_short PF00106.20 EPE28537.1 - 3.9e-17 62.6 0.0 5.3e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE28537.1 - 3.3e-06 26.9 0.0 4.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE28537.1 - 0.002 17.5 0.0 0.0043 16.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPE28537.1 - 0.095 11.9 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Diphthamide_syn PF01866.12 EPE28538.1 - 3e-113 378.0 0.0 3.9e-113 377.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Lactamase_B PF00753.22 EPE28539.1 - 3.4e-08 33.3 0.0 5.6e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPE28539.1 - 0.00057 19.4 0.0 0.0011 18.4 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain adh_short PF00106.20 EPE28540.1 - 3.3e-25 88.9 0.6 6e-25 88.0 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE28540.1 - 1.2e-22 80.8 1.1 1.4e-22 80.6 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE28540.1 - 8.4e-10 38.5 0.4 1.3e-09 37.9 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE28540.1 - 0.00054 19.4 0.2 0.0031 17.0 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HEM4 PF02602.10 EPE28540.1 - 0.015 14.5 0.1 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD ICL PF00463.16 EPE28541.1 - 1.3e-279 927.8 0.2 1.5e-279 927.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EPE28541.1 - 5.1e-12 45.5 0.1 6.3e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.13 EPE28542.1 - 1.7e-187 624.1 0.1 2e-187 623.9 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EPE28542.1 - 2.8e-16 58.5 0.1 4.4e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.1 EPE28542.1 - 0.11 12.3 0.0 5.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix domain Glyco_trans_2_3 PF13632.1 EPE28543.1 - 7.7e-47 159.5 5.3 2.1e-46 158.0 3.6 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EPE28543.1 - 0.00018 21.2 0.0 0.00058 19.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EPE28543.1 - 0.00019 20.7 0.0 0.00041 19.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF3936 PF13072.1 EPE28545.1 - 0.16 11.4 0.1 0.35 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) Asp_protease_2 PF13650.1 EPE28548.1 - 0.02 15.3 0.1 0.068 13.6 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 EPE28548.1 - 0.1 12.4 0.0 0.57 10.0 0.0 2.3 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease Sugar_tr PF00083.19 EPE28550.1 - 8.3e-78 261.9 14.8 9.5e-78 261.7 10.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE28550.1 - 2.6e-21 75.7 32.5 1.2e-17 63.7 3.4 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EPE28550.1 - 0.0011 18.8 1.7 0.92 9.5 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) DUF4181 PF13789.1 EPE28550.1 - 0.99 9.3 6.3 0.26 11.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) Acetyltransf_1 PF00583.19 EPE28552.1 - 4.4e-07 29.8 0.0 7.5e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE28552.1 - 2.1e-06 27.8 0.0 9.9e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPE28552.1 - 1.3e-05 25.2 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE28552.1 - 0.0062 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EPE28552.1 - 0.015 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family FR47 PF08445.5 EPE28552.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Fungal_trans_2 PF11951.3 EPE28553.1 - 3.6e-35 121.3 5.9 2.1e-19 69.3 0.2 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE28553.1 - 9.5e-10 38.2 10.0 1.6e-09 37.5 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAP PF02037.22 EPE28554.1 - 3.9e-18 64.4 7.0 1.5e-08 33.8 0.1 4.3 3 1 1 4 4 4 2 SAP domain Telomere_Sde2_2 PF13297.1 EPE28554.1 - 0.00035 19.7 0.2 0.00035 19.7 0.1 2.9 4 0 0 4 4 4 1 Telomere stability C-terminal Barttin PF15462.1 EPE28554.1 - 1.1 8.8 5.3 0.38 10.3 0.7 2.0 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) HTH_22 PF13309.1 EPE28555.1 - 0.083 12.6 0.6 0.33 10.7 0.0 2.3 2 1 0 2 2 2 0 HTH domain RRM_1 PF00076.17 EPE28557.1 - 4.8e-21 74.1 0.1 4.4e-10 39.0 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE28557.1 - 2.9e-20 72.0 0.0 1.5e-08 34.5 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE28557.1 - 1.7e-06 27.7 0.0 0.0044 16.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ino80_Iec3 PF14612.1 EPE28558.1 - 1.4e-55 188.8 0.4 3e-55 187.7 0.2 1.5 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Iso_dh PF00180.15 EPE28559.1 - 1.6e-70 237.8 0.0 1.8e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase M_domain PF12938.2 EPE28560.1 - 0.43 10.3 5.3 0.12 12.1 1.6 1.5 2 0 0 2 2 2 0 M domain of GW182 Not3 PF04065.10 EPE28562.1 - 4.4e-101 337.0 26.4 8.1e-101 336.1 18.3 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EPE28562.1 - 4.6e-43 146.3 12.0 1.8e-42 144.4 8.3 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 EPE28562.1 - 0.0026 17.2 2.5 0.0061 16.0 1.8 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Poty_PP PF08440.5 EPE28562.1 - 0.029 13.4 1.8 0.073 12.1 1.2 1.6 1 0 0 1 1 1 0 Potyviridae polyprotein Cep57_MT_bd PF06657.8 EPE28562.1 - 0.031 14.1 1.1 0.031 14.1 0.7 2.9 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Snapin_Pallidin PF14712.1 EPE28562.1 - 0.29 11.4 13.0 0.79 10.0 0.3 3.4 3 0 0 3 3 3 0 Snapin/Pallidin Syntaxin_2 PF14523.1 EPE28562.1 - 2 8.5 12.0 0.11 12.4 3.2 2.7 3 0 0 3 3 3 0 Syntaxin-like protein Sec5 PF15469.1 EPE28562.1 - 3.8 7.1 11.7 0.58 9.8 1.7 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 Tyr_Deacylase PF02580.11 EPE28563.1 - 2e-46 157.5 0.3 2.2e-46 157.4 0.2 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.16 EPE28564.1 - 2.5e-46 157.6 0.4 3.8e-46 157.1 0.3 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EPE28564.1 - 0.00016 21.2 4.5 0.069 12.8 0.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.1 EPE28564.1 - 0.028 14.1 0.0 0.11 12.3 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPE28564.1 - 0.03 14.2 3.8 0.16 11.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RasGAP PF00616.14 EPE28565.1 - 8.5e-43 146.3 0.0 1.8e-42 145.2 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EPE28565.1 - 8.4e-05 22.3 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain MRP-L20 PF12824.2 EPE28567.1 - 6.1e-47 159.6 5.4 7.2e-47 159.3 3.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_38 PF13936.1 EPE28567.1 - 0.0054 16.2 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4158 PF13700.1 EPE28567.1 - 0.049 13.1 0.3 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) ZZ PF00569.12 EPE28568.1 - 2.8e-20 71.5 48.4 5.7e-06 25.7 4.6 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type Btz PF09405.5 EPE28569.1 - 1.9e-27 95.8 3.0 1.9e-27 95.8 2.1 1.9 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Aft1_HRA PF11786.3 EPE28570.1 - 4.1e-27 94.2 6.7 4.1e-27 94.2 4.6 2.8 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.3 EPE28570.1 - 2.2e-16 60.6 1.8 2.2e-16 60.6 1.2 3.7 3 2 2 5 5 5 1 Aft1 HRR domain bZIP_1 PF00170.16 EPE28570.1 - 2.2e-14 53.1 4.7 4e-14 52.3 3.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 EPE28570.1 - 2.5e-08 34.2 5.5 2.5e-08 34.2 3.8 3.7 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EPE28570.1 - 2.9e-07 30.1 6.5 5.2e-07 29.3 4.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPE28570.1 - 0.00033 20.8 3.7 0.00087 19.5 2.5 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF972 PF06156.8 EPE28570.1 - 0.056 13.7 0.2 0.056 13.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Macoilin PF09726.4 EPE28570.1 - 1.9 6.7 13.3 2.4 6.3 9.2 1.1 1 0 0 1 1 1 0 Transmembrane protein GST_N_3 PF13417.1 EPE28571.1 - 4.4e-12 46.0 0.3 8e-12 45.2 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPE28571.1 - 0.00032 20.6 0.0 0.00052 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPE28571.1 - 0.0027 17.6 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE28571.1 - 0.029 14.2 0.1 0.052 13.4 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NACHT PF05729.7 EPE28572.1 - 8.8e-09 35.2 0.1 7.9e-05 22.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain Abhydrolase_5 PF12695.2 EPE28572.1 - 2.7e-05 23.9 0.0 5.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 EPE28572.1 - 0.00023 21.1 0.0 0.00085 19.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EPE28572.1 - 0.00041 19.3 0.0 0.0011 17.9 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain Abhydrolase_6 PF12697.2 EPE28572.1 - 0.00042 20.2 0.0 0.00097 19.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family ABC_tran PF00005.22 EPE28572.1 - 0.00067 19.9 0.0 0.0025 18.1 0.0 2.0 1 0 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 EPE28572.1 - 0.0008 19.1 0.0 0.0052 16.5 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EPE28572.1 - 0.00098 19.2 0.0 0.0055 16.8 0.0 2.3 2 0 0 2 2 1 1 AAA domain DUF900 PF05990.7 EPE28572.1 - 0.0012 18.2 0.0 0.023 13.9 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) AAA_10 PF12846.2 EPE28572.1 - 0.01 15.3 0.0 0.03 13.7 0.0 1.8 1 0 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 EPE28572.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain PGAP1 PF07819.8 EPE28572.1 - 0.015 14.9 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein AAA_29 PF13555.1 EPE28572.1 - 0.016 14.6 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EPE28572.1 - 0.032 13.9 0.1 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF676 PF05057.9 EPE28572.1 - 0.047 12.9 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RNA_helicase PF00910.17 EPE28572.1 - 0.051 13.7 1.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Cutinase PF01083.17 EPE28572.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase Thioesterase PF00975.15 EPE28572.1 - 0.12 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain Viral_helicase1 PF01443.13 EPE28572.1 - 0.13 11.7 0.0 0.39 10.2 0.0 1.8 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TFIIA_gamma_C PF02751.9 EPE28572.1 - 0.13 12.0 1.5 8 6.3 0.1 2.6 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit AAA_30 PF13604.1 EPE28572.1 - 0.35 10.4 0.0 0.65 9.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DWNN PF08783.6 EPE28573.1 - 1.9e-30 104.6 0.0 5.5e-30 103.1 0.0 1.8 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EPE28573.1 - 6.6e-05 22.3 3.1 0.00019 20.8 2.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EPE28573.1 - 0.0047 16.7 1.3 0.009 15.8 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.10 EPE28573.1 - 0.0052 16.7 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-RING_6 PF14835.1 EPE28573.1 - 0.0067 16.1 2.1 0.012 15.3 1.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF737 PF05300.6 EPE28573.1 - 0.019 14.9 0.6 0.019 14.9 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF737) GRP PF07172.6 EPE28573.1 - 0.19 12.2 19.0 0.11 13.0 11.3 1.9 2 0 0 2 2 1 0 Glycine rich protein family zf-Nse PF11789.3 EPE28573.1 - 0.32 10.5 4.6 0.7 9.4 3.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EPE28573.1 - 1.3 8.7 9.4 2.8 7.6 6.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPE28573.1 - 2 8.3 9.1 5.9 6.8 6.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EPE28573.1 - 3.4 7.7 16.4 0.079 13.0 6.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HJURP_mid PF12346.3 EPE28577.1 - 0.002 18.2 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction recognition protein-associated repeat T2SM PF04612.7 EPE28577.1 - 0.047 13.4 0.6 0.14 11.9 0.4 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Yippee-Mis18 PF03226.9 EPE28578.1 - 9e-19 67.3 0.0 1.5e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Sorting_nexin PF03700.8 EPE28578.1 - 0.049 13.7 0.3 0.049 13.7 0.2 2.0 2 0 0 2 2 2 0 Sorting nexin, N-terminal domain PIF1 PF05970.9 EPE28579.1 - 1.1e-40 139.6 1.6 7.4e-28 97.5 0.0 3.7 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 EPE28579.1 - 3.3e-15 56.2 0.0 1.1e-12 47.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Cauli_VI PF01693.11 EPE28579.1 - 1.2e-12 47.6 0.3 2.8e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin AAA_19 PF13245.1 EPE28579.1 - 5.9e-07 29.1 0.0 1.8e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EPE28579.1 - 1.3e-05 25.3 0.0 2.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EPE28579.1 - 0.00034 19.5 0.0 0.00074 18.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.1 EPE28579.1 - 0.00092 18.8 1.1 0.43 10.1 0.1 2.9 2 1 0 3 3 3 1 AAA domain DEAD PF00270.24 EPE28579.1 - 0.0018 17.7 0.2 0.02 14.3 0.1 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.1 EPE28579.1 - 0.0025 17.8 0.0 0.0066 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Pox_A32 PF04665.7 EPE28579.1 - 0.01 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein TrwB_AAD_bind PF10412.4 EPE28579.1 - 0.011 14.4 0.0 0.026 13.1 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 EPE28579.1 - 0.014 14.9 0.0 0.038 13.4 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.7 EPE28579.1 - 0.019 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 EPE28579.1 - 0.02 14.0 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF853 PF05872.7 EPE28579.1 - 0.022 13.1 0.0 0.035 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) NB-ARC PF00931.17 EPE28579.1 - 0.022 13.6 0.0 0.068 12.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.4 EPE28579.1 - 0.023 13.6 0.0 0.2 10.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 EPE28579.1 - 0.027 14.5 0.0 0.13 12.3 0.0 2.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 EPE28579.1 - 0.034 13.8 0.0 6.9 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EPE28579.1 - 0.034 14.3 0.0 2.7 8.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EPE28579.1 - 0.036 13.2 0.0 0.08 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Herpes_Helicase PF02689.9 EPE28579.1 - 0.037 11.7 0.1 0.44 8.2 0.0 2.0 2 0 0 2 2 2 0 Helicase UPF0079 PF02367.12 EPE28579.1 - 0.065 12.8 0.1 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 EPE28579.1 - 0.077 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD-helicase PF00580.16 EPE28579.1 - 0.099 11.9 0.9 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_14 PF13173.1 EPE28579.1 - 0.1 12.5 0.0 0.3 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EPE28579.1 - 0.12 11.8 0.0 0.75 9.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ODC_AZ PF02100.12 EPE28580.1 - 5.7e-26 90.1 0.0 8.1e-26 89.6 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF4355 PF14265.1 EPE28581.1 - 0.74 9.7 16.9 1.8 8.5 7.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) Aminotran_4 PF01063.14 EPE28581.1 - 1.1 8.7 4.5 0.49 9.8 0.9 1.9 1 1 1 2 2 2 0 Aminotransferase class IV AA_permease PF00324.16 EPE28583.1 - 2.5e-112 375.6 43.8 3.1e-112 375.3 30.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE28583.1 - 6.8e-26 90.7 43.4 8.2e-26 90.5 30.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF218 PF02698.12 EPE28584.1 - 9e-08 31.7 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Plus-3 PF03126.13 EPE28586.1 - 1.6e-32 111.7 0.0 3.6e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain COQ7 PF03232.8 EPE28587.1 - 1.8e-64 216.3 0.1 2.6e-64 215.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 UPF0184 PF03670.8 EPE28587.1 - 0.002 18.2 0.2 0.0032 17.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) Rubrerythrin PF02915.12 EPE28587.1 - 0.011 16.0 0.1 0.021 15.1 0.0 1.6 2 0 0 2 2 2 0 Rubrerythrin PLDc PF00614.17 EPE28588.1 - 2.7e-15 55.5 1.3 8.7e-08 31.7 0.1 2.8 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EPE28588.1 - 2.1e-12 46.9 0.0 2.1e-07 30.7 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EPE28588.1 - 1.8e-07 30.9 0.0 1.2e-06 28.3 0.0 2.4 2 1 0 2 2 2 1 PX domain Abhydrolase_6 PF12697.2 EPE28589.1 - 6.1e-07 29.5 0.0 7.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE28589.1 - 1e-05 25.3 0.0 2e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE28589.1 - 0.046 12.9 0.0 8.6 5.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.13 EPE28589.1 - 0.053 12.8 0.0 4.1 6.6 0.0 3.0 3 1 0 3 3 3 0 Dienelactone hydrolase family zf-CCCH PF00642.19 EPE28590.1 - 0.0011 18.5 4.7 0.0018 17.8 3.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sec1 PF00995.18 EPE28591.1 - 1.4e-154 515.8 0.0 1.8e-154 515.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Pox_A21 PF05323.7 EPE28592.1 - 3.2 8.1 5.3 0.45 10.9 0.8 1.7 2 0 0 2 2 2 0 Poxvirus A21 Protein CBM_1 PF00734.13 EPE28594.1 - 3.9e-09 35.9 12.0 9.5e-09 34.7 8.3 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Pro-kuma_activ PF09286.6 EPE28595.1 - 6.4e-38 130.0 0.1 1.4e-37 128.9 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EPE28595.1 - 1.1e-08 34.5 0.0 2.6e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Subtilase family DUF3757 PF12582.3 EPE28595.1 - 0.14 12.3 0.1 0.51 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3757) LMWPc PF01451.16 EPE28596.1 - 4.7e-38 130.6 0.0 5.3e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Chitin_synth_1 PF01644.12 EPE28597.1 - 5.3e-83 276.6 0.3 8e-83 276.1 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EPE28597.1 - 3.2e-31 106.8 0.0 5.8e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EPE28597.1 - 5.9e-22 77.7 3.9 1.7e-18 66.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EPE28597.1 - 3.6e-08 33.5 0.0 1.8e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EPE28597.1 - 1.2e-06 28.3 11.9 1.2e-06 28.3 8.3 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 ATP_synt_H PF05493.8 EPE28597.1 - 1.8 8.7 10.9 8.8 6.4 4.0 2.8 2 0 0 2 2 2 0 ATP synthase subunit H G_glu_transpept PF01019.16 EPE28598.1 - 6.4e-146 486.8 0.0 7.5e-146 486.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase RF-1 PF00472.15 EPE28599.1 - 1.2e-32 112.1 2.9 1.2e-32 112.1 2.0 2.0 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 EPE28599.1 - 4e-30 103.8 1.9 5.3e-30 103.4 0.0 2.2 3 0 0 3 3 3 1 PCRF domain MIR PF02815.14 EPE28599.1 - 0.02 14.4 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 MIR domain Toxin_52 PF15605.1 EPE28599.1 - 0.23 11.3 2.3 0.24 11.3 0.4 1.9 2 0 0 2 2 2 0 Putative toxin 52 DUF3328 PF11807.3 EPE28600.1 - 2.2e-27 96.1 0.0 2.8e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AKAP7_RIRII_bdg PF10470.4 EPE28600.1 - 0.042 13.6 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Peptidase_S10 PF00450.17 EPE28601.1 - 2.9e-91 306.7 0.1 3.9e-91 306.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Aminotran_4 PF01063.14 EPE28602.1 - 2e-23 83.0 0.0 4.1e-23 82.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 EPE28603.1 - 3.7e-63 209.0 39.6 6.9e-14 51.2 1.1 6.8 3 3 5 8 8 8 8 TPR repeat TPR_1 PF00515.23 EPE28603.1 - 2.4e-45 150.3 29.5 5e-06 25.8 0.0 11.5 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 EPE28603.1 - 3.3e-44 145.2 27.4 9.5e-05 22.0 0.0 11.5 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_12 PF13424.1 EPE28603.1 - 9.9e-29 99.1 27.7 4.8e-08 32.8 0.1 7.5 2 2 5 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 EPE28603.1 - 1e-24 86.5 15.8 2.7e-07 31.0 0.1 7.1 5 2 3 8 8 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 EPE28603.1 - 1.6e-24 83.9 11.6 0.0006 19.8 0.0 9.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EPE28603.1 - 3e-18 64.1 20.0 0.015 15.0 0.1 10.5 10 1 1 11 11 11 3 Tetratricopeptide repeat Apc3 PF12895.2 EPE28603.1 - 1.1e-16 60.7 17.6 0.00025 21.1 1.3 5.4 2 1 4 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EPE28603.1 - 5.7e-15 53.8 20.5 0.045 13.5 0.1 9.5 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPE28603.1 - 6.6e-14 51.1 17.1 0.049 14.2 0.0 9.9 3 3 8 11 11 11 4 Tetratricopeptide repeat TPR_9 PF13371.1 EPE28603.1 - 6.9e-13 48.2 10.2 1.5e-05 24.7 0.1 6.8 3 2 3 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPE28603.1 - 1.4e-12 47.7 20.8 3.1e-06 27.4 0.3 6.6 4 2 1 6 6 6 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 EPE28603.1 - 2.8e-06 26.4 11.3 0.14 11.3 0.0 6.8 6 0 0 6 6 6 1 SHNi-TPR TPR_15 PF13429.1 EPE28603.1 - 2.4e-05 23.5 8.1 0.15 11.1 0.6 4.7 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPE28603.1 - 0.00011 22.3 25.4 3.2 8.4 0.0 9.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_4 PF07721.9 EPE28603.1 - 0.00057 20.0 0.4 45 4.8 0.0 6.0 7 0 0 7 7 4 0 Tetratricopeptide repeat BLVR PF06375.6 EPE28603.1 - 0.0013 18.5 1.0 0.0013 18.5 0.7 1.9 2 0 0 2 2 2 1 Bovine leukaemia virus receptor (BLVR) TPR_10 PF13374.1 EPE28603.1 - 0.0046 16.8 15.1 2 8.4 0.2 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF3856 PF12968.2 EPE28603.1 - 0.005 16.6 12.1 9 6.1 0.0 6.3 4 1 1 7 7 6 0 Domain of Unknown Function (DUF3856) MAS20 PF02064.10 EPE28603.1 - 0.085 12.7 1.1 55 3.6 0.0 3.9 3 1 0 3 3 3 0 MAS20 protein import receptor Apc5 PF12862.2 EPE28603.1 - 0.34 10.7 7.2 6.7 6.6 0.2 4.1 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_3 PF07720.7 EPE28603.1 - 2.1 8.2 16.2 30 4.5 0.5 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.7 EPE28603.1 - 5.1 7.8 12.1 10 6.9 0.0 5.0 4 0 0 4 4 4 0 Sel1 repeat DUF3455 PF11937.3 EPE28605.1 - 7.6e-36 123.7 0.1 1.1e-35 123.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) HET PF06985.6 EPE28606.1 - 1.5e-37 128.8 1.0 3.1e-37 127.8 0.7 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PS_Dcarbxylase PF02666.10 EPE28606.1 - 0.19 11.0 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase Pkinase PF00069.20 EPE28608.1 - 8.5e-71 238.1 0.0 1e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE28608.1 - 7.6e-31 107.1 0.0 1.3e-30 106.3 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EPE28608.1 - 0.019 14.6 0.1 0.068 12.8 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family EHN PF06441.7 EPE28611.1 - 7.7e-31 106.3 0.1 1.5e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EPE28611.1 - 3.7e-12 46.6 0.0 7.6e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE28611.1 - 4.6e-11 42.7 0.0 8.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold FYVE PF01363.16 EPE28612.1 - 0.0018 18.1 7.1 0.0018 18.1 4.9 2.4 2 0 0 2 2 2 1 FYVE zinc finger PHD_3 PF13922.1 EPE28612.1 - 0.09 13.0 0.3 0.09 13.0 0.2 2.2 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx FYVE_2 PF02318.11 EPE28612.1 - 3.9 7.3 8.8 5.7 6.8 1.4 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Mid2 PF04478.7 EPE28613.1 - 0.003 16.9 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF543 PF04418.7 EPE28613.1 - 0.021 14.7 2.4 3 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Sulfate_transp PF00916.15 EPE28614.1 - 1.6e-08 33.9 3.5 1.1e-06 27.8 0.4 2.6 2 0 0 2 2 2 2 Sulfate transporter family Xan_ur_permease PF00860.15 EPE28614.1 - 4.3e-06 25.4 23.5 5.1e-05 21.9 8.5 2.2 1 1 0 2 2 2 2 Permease family BenE PF03594.8 EPE28614.1 - 0.0039 15.8 10.9 0.038 12.5 3.4 2.9 2 1 0 2 2 2 2 Benzoate membrane transport protein MRC1 PF09444.5 EPE28615.1 - 3.6e-37 127.9 18.1 3.6e-37 127.9 12.5 6.5 5 2 0 6 6 6 1 MRC1-like domain Ribosomal_L22 PF00237.14 EPE28616.1 - 1.2e-18 66.9 2.5 7.2e-09 35.5 0.7 2.6 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e LEA_2 PF03168.8 EPE28616.1 - 0.039 14.3 0.2 0.16 12.3 0.0 2.0 1 1 1 2 2 2 0 Late embryogenesis abundant protein RRM_1 PF00076.17 EPE28617.1 - 2.4e-42 142.4 0.1 1.5e-14 53.3 0.1 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE28617.1 - 1.5e-38 130.5 0.1 3e-12 46.3 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE28617.1 - 1.6e-18 66.2 0.0 2.7e-05 23.9 0.0 5.7 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPE28617.1 - 6.1e-08 32.3 0.0 0.005 16.5 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 EPE28617.1 - 0.04 13.3 0.1 0.04 13.3 0.1 2.6 2 0 0 2 2 2 0 Lsm interaction motif BTB PF00651.26 EPE28619.1 - 0.0032 17.4 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain YGGT PF02325.12 EPE28620.1 - 0.025 14.4 1.6 0.069 13.0 0.1 2.4 2 0 0 2 2 2 0 YGGT family FUSC_2 PF13515.1 EPE28620.1 - 0.41 10.5 9.9 0.071 13.0 3.1 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein-like adh_short_C2 PF13561.1 EPE28621.1 - 2.6e-31 109.2 0.4 3.1e-31 108.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE28621.1 - 1e-22 80.8 0.2 1.4e-22 80.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE28621.1 - 0.00072 19.2 0.1 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_18 PF12847.2 EPE28621.1 - 0.0065 17.0 0.1 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE28621.1 - 0.014 15.8 0.1 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EPE28621.1 - 0.023 14.7 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ATP-synt_C PF00137.16 EPE28621.1 - 0.13 12.2 3.7 0.25 11.2 2.6 1.4 1 0 0 1 1 1 0 ATP synthase subunit C Glyoxalase_2 PF12681.2 EPE28622.1 - 1.1e-15 58.2 0.0 1.4e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EPE28622.1 - 1.8e-08 34.4 0.0 6.8e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EPE28622.1 - 0.093 12.6 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain UTP15_C PF09384.5 EPE28623.1 - 2.6e-46 156.9 0.0 4.3e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EPE28623.1 - 1.6e-31 106.9 0.4 8e-09 35.0 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Utp12 PF04003.7 EPE28623.1 - 0.0039 17.0 0.2 0.042 13.7 0.2 2.2 1 1 0 1 1 1 1 Dip2/Utp12 Family ATP-synt_E PF05680.7 EPE28623.1 - 0.015 15.2 0.3 0.03 14.2 0.2 1.4 1 0 0 1 1 1 0 ATP synthase E chain L31 PF09784.4 EPE28623.1 - 0.051 13.6 2.0 0.41 10.7 0.3 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 bZIP_1 PF00170.16 EPE28624.1 - 0.01 15.7 1.3 0.023 14.6 0.9 1.6 1 0 0 1 1 1 0 bZIP transcription factor AT_hook PF02178.14 EPE28624.1 - 0.014 14.9 0.7 0.034 13.7 0.5 1.7 1 0 0 1 1 1 0 AT hook motif Ku_PK_bind PF08785.6 EPE28626.1 - 0.098 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Ku C terminal domain like Cript PF10235.4 EPE28627.1 - 4.5e-31 107.0 10.2 4.5e-31 107.0 7.1 1.3 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 EPE28627.1 - 0.0035 17.1 19.6 0.015 15.0 5.9 2.5 2 1 1 3 3 3 2 Double zinc ribbon zf-ribbon_3 PF13248.1 EPE28627.1 - 0.05 12.8 7.9 16 4.8 3.8 3.2 2 1 1 3 3 3 0 zinc-ribbon domain MRVI1 PF05781.7 EPE28627.1 - 0.059 11.7 1.3 0.058 11.7 0.9 1.0 1 0 0 1 1 1 0 MRVI1 protein zinc_ribbon_2 PF13240.1 EPE28627.1 - 0.073 12.5 1.7 0.073 12.5 1.2 3.2 2 1 1 3 3 3 0 zinc-ribbon domain DUF1272 PF06906.6 EPE28627.1 - 4.9 7.0 9.2 0.7 9.7 3.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) HAD PF12710.2 EPE28628.1 - 1.8e-20 73.9 0.1 4.8e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EPE28628.1 - 1.7e-19 69.7 0.0 3e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EPE28628.1 - 1.1e-14 55.3 0.2 8.4e-14 52.4 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPE28628.1 - 4e-12 45.9 0.0 9.6e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPE28628.1 - 0.00086 18.9 0.1 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPE28628.1 - 0.02 15.1 0.1 0.07 13.3 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Homeobox_KN PF05920.6 EPE28630.1 - 1.7e-18 66.0 0.6 9.6e-18 63.6 0.4 2.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EPE28630.1 - 7.7e-08 31.8 1.1 2.3e-07 30.3 0.8 1.8 1 0 0 1 1 1 1 Homeobox domain Drf_FH1 PF06346.7 EPE28631.1 - 8e-05 22.2 8.0 8e-05 22.2 5.6 4.5 3 1 1 4 4 4 2 Formin Homology Region 1 DIM PF08194.7 EPE28633.1 - 0.013 15.4 1.5 0.029 14.3 1.0 1.6 1 0 0 1 1 1 0 DIM protein Excalibur PF05901.6 EPE28636.1 - 0.23 11.8 5.6 57 4.1 0.1 4.2 4 0 0 4 4 4 0 Excalibur calcium-binding domain YpzI PF14140.1 EPE28636.1 - 1.6 8.2 6.4 1.7 8.2 0.0 3.6 4 0 0 4 4 4 0 YpzI-like protein Ish1 PF10281.4 EPE28637.1 - 7.5e-88 288.1 20.9 6.6e-13 48.4 0.2 8.6 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EPE28637.1 - 7.6e-15 54.1 0.0 0.00089 18.7 0.0 7.0 7 0 0 7 7 7 4 HeH/LEM domain SAP PF02037.22 EPE28637.1 - 6.4e-14 51.0 0.0 0.085 12.3 0.0 8.0 7 2 0 7 7 7 4 SAP domain Slx4 PF09494.5 EPE28637.1 - 2.3e-08 33.6 1.6 1.2 8.9 0.0 6.5 6 0 0 6 6 6 2 Slx4 endonuclease APC2 PF08672.6 EPE28637.1 - 3.3e-06 27.2 1.5 15 5.9 0.0 6.5 7 0 0 7 7 7 1 Anaphase promoting complex (APC) subunit 2 Endonuc-dimeris PF09124.5 EPE28637.1 - 0.046 13.3 0.0 7.5 6.2 0.0 4.1 5 0 0 5 5 5 0 T4 recombination endonuclease VII, dimerisation DUF905 PF06006.7 EPE28637.1 - 0.072 12.4 0.3 27 4.2 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF905) SAM_2 PF07647.12 EPE28637.1 - 7.8 6.4 6.7 15 5.4 0.0 4.5 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) AMP-binding PF00501.23 EPE28638.1 - 3e-70 236.7 0.0 6.6e-70 235.5 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE28638.1 - 0.0051 17.7 0.2 0.011 16.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Condensation PF00668.15 EPE28638.1 - 0.0092 14.8 0.4 0.023 13.5 0.1 1.7 2 0 0 2 2 2 1 Condensation domain MIF4G_like PF09088.6 EPE28638.1 - 0.094 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 MIF4G like MFS_1 PF07690.11 EPE28639.1 - 7.4e-44 149.8 27.6 1.5e-37 129.1 13.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EPE28639.1 - 2.9e-05 22.9 1.3 2.9e-05 22.9 0.9 2.4 1 1 1 2 2 2 1 BT1 family MFS_2 PF13347.1 EPE28639.1 - 4.7e-05 21.9 24.7 0.0044 15.4 9.4 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 EPE28639.1 - 0.25 9.4 26.8 1.6 6.7 15.2 2.9 1 1 1 2 2 2 0 Transmembrane secretion effector AP_endonuc_2 PF01261.19 EPE28640.1 - 1.7e-22 79.7 0.0 2.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Trypsin PF00089.21 EPE28641.1 - 1.8e-63 214.0 7.6 2.1e-63 213.8 5.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EPE28641.1 - 5.5e-06 26.3 0.9 1.6e-05 24.8 0.6 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain CFEM PF05730.6 EPE28642.1 - 2.1e-09 37.0 12.2 3.2e-09 36.4 8.5 1.3 1 0 0 1 1 1 1 CFEM domain Shisa PF13908.1 EPE28642.1 - 1.7e-05 25.0 5.5 3.2e-05 24.1 3.8 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EPE28642.1 - 0.0016 18.7 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1049 PF06305.6 EPE28642.1 - 0.0024 17.3 0.2 0.0047 16.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) Peptidase_M56 PF05569.6 EPE28642.1 - 0.022 13.7 0.2 0.029 13.3 0.2 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 MGC-24 PF05283.6 EPE28642.1 - 0.092 12.5 13.9 0.18 11.6 9.7 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) CD34_antigen PF06365.7 EPE28642.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family gpUL132 PF11359.3 EPE28642.1 - 0.4 9.9 3.7 0.14 11.4 0.3 1.7 1 1 1 2 2 2 0 Glycoprotein UL132 PAT1 PF09770.4 EPE28642.1 - 4.8 5.2 13.4 6.3 4.8 9.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box-like PF12937.2 EPE28644.1 - 0.059 13.0 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 F-box-like Ank_2 PF12796.2 EPE28645.1 - 2.3e-22 79.1 0.0 1e-17 64.2 0.0 3.7 2 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE28645.1 - 1.6e-17 62.3 1.8 9.3e-08 31.5 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EPE28645.1 - 3.6e-13 49.6 1.2 1.2e-06 28.9 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE28645.1 - 1.6e-12 46.3 0.7 7.9e-05 22.5 0.1 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EPE28645.1 - 1.5e-10 40.9 3.4 1.1e-05 25.5 0.2 4.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) F-box-like PF12937.2 EPE28645.1 - 0.046 13.4 0.8 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 F-box-like PGA_cap PF09587.5 EPE28645.1 - 0.095 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap CAP59_mtransfer PF11735.3 EPE28646.1 - 1.5e-59 201.1 0.0 2e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Abhydrolase_6 PF12697.2 EPE28647.1 - 1.3e-16 61.1 0.1 1.6e-16 60.8 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE28647.1 - 6.5e-07 29.2 0.1 1e-06 28.5 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF498 PF04430.9 EPE28647.1 - 0.088 12.3 0.1 22 4.6 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF498/DUF598) DUF1356 PF07092.7 EPE28647.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) tRNA-synt_1b PF00579.20 EPE28648.1 - 1.1e-21 77.3 1.1 3.9e-21 75.4 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) PRELI PF04707.9 EPE28649.1 - 1.6e-22 79.7 0.1 7.6e-21 74.3 0.0 2.3 2 0 0 2 2 2 2 PRELI-like family Asp PF00026.18 EPE28650.1 - 2.3e-61 207.7 3.8 2.8e-61 207.4 2.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPE28650.1 - 1.3e-05 25.2 0.1 0.00017 21.5 0.0 2.6 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Kinesin PF00225.18 EPE28653.1 - 2.7e-107 358.3 5.9 6.8e-107 357.0 4.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain Filament PF00038.16 EPE28653.1 - 7.1e-05 22.4 32.4 7.1e-05 22.4 22.5 2.3 2 1 0 2 2 2 1 Intermediate filament protein Pyr_redox_3 PF13738.1 EPE28654.1 - 2.2e-22 80.1 0.0 6.4e-21 75.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE28654.1 - 8.4e-14 50.6 0.0 5e-13 48.1 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPE28654.1 - 2e-13 49.9 0.0 3.5e-11 42.6 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPE28654.1 - 3.7e-09 36.7 0.0 7e-09 35.8 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE28654.1 - 3.4e-06 26.2 0.1 0.037 12.9 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE28654.1 - 1.6e-05 24.8 0.0 4.9e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPE28654.1 - 2e-05 24.4 0.0 0.0032 17.2 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EPE28654.1 - 0.01 14.9 0.1 0.018 14.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EPE28654.1 - 0.011 14.1 0.1 0.46 8.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.19 EPE28654.1 - 0.075 12.0 0.0 2.9 6.8 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EPE28654.1 - 0.13 11.1 0.1 0.4 9.5 0.1 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPE28654.1 - 0.22 10.3 0.0 11 4.7 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_4 PF01565.18 EPE28656.1 - 3.8e-18 65.3 3.0 3.8e-18 65.3 2.1 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPE28656.1 - 2e-11 43.6 0.3 5.8e-11 42.1 0.2 1.9 1 0 0 1 1 1 1 Berberine and berberine like Zn_clus PF00172.13 EPE28657.1 - 0.0049 16.7 7.3 0.011 15.6 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE28657.1 - 0.04 12.5 0.1 0.045 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Toxin_18 PF08087.6 EPE28657.1 - 0.075 12.8 0.3 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Conotoxin O-superfamily RTA1 PF04479.8 EPE28658.1 - 7.7e-27 94.2 8.2 1.2e-26 93.6 5.7 1.2 1 0 0 1 1 1 1 RTA1 like protein EF-hand_1 PF00036.27 EPE28659.1 - 3.4e-06 25.9 0.0 0.0088 15.2 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EPE28659.1 - 7.6e-06 25.9 0.0 2.8e-05 24.1 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPE28659.1 - 5.9e-05 22.6 0.0 0.49 10.4 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain WW PF00397.21 EPE28659.1 - 0.00039 20.2 2.6 0.016 15.0 0.0 3.0 3 0 0 3 3 3 1 WW domain EF-hand_5 PF13202.1 EPE28659.1 - 0.024 13.9 0.0 0.11 11.8 0.0 2.2 1 0 0 1 1 1 0 EF hand DUF2450 PF10475.4 EPE28659.1 - 0.047 12.5 0.8 0.37 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Antimicrobial10 PF08105.6 EPE28660.1 - 0.1 12.2 0.1 0.36 10.4 0.0 1.9 1 0 0 1 1 1 0 Metchnikowin family Methyltransf_23 PF13489.1 EPE28661.1 - 0.00052 19.7 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE28661.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.24 EPE28662.1 - 1.5e-44 151.4 0.0 7.5e-42 142.6 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE28662.1 - 9.2e-22 76.7 0.1 3.5e-21 74.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE28662.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EPE28662.1 - 0.012 14.8 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain WSC PF01822.14 EPE28663.1 - 2.2e-70 232.5 86.0 2.3e-18 65.8 8.5 8.6 8 1 0 8 8 8 5 WSC domain PQQ_3 PF13570.1 EPE28663.1 - 7.2e-06 26.1 8.5 0.022 15.0 0.0 5.0 4 0 0 4 4 4 2 PQQ-like domain FAD_binding_3 PF01494.14 EPE28664.1 - 1.3e-79 267.8 0.0 1.7e-79 267.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EPE28664.1 - 2.7e-47 160.5 0.0 4.4e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EPE28664.1 - 0.0037 16.1 0.0 0.77 8.5 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.1 EPE28664.1 - 0.0046 16.9 1.3 0.029 14.3 0.1 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPE28664.1 - 0.0066 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EPE28664.1 - 0.0078 16.1 0.0 0.017 14.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE28664.1 - 0.017 14.0 0.2 0.038 12.9 0.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EPE28664.1 - 0.025 13.6 0.2 0.051 12.6 0.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE28664.1 - 0.027 13.3 0.0 0.058 12.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain FtsL PF04999.8 EPE28665.1 - 0.093 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Cell division protein FtsL DUF997 PF06196.7 EPE28665.1 - 0.15 11.6 1.6 1 8.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF997) MFS_1 PF07690.11 EPE28666.1 - 1.1e-29 103.2 31.0 1.1e-29 103.2 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EPE28667.1 - 6.6e-40 136.9 53.7 6.6e-40 136.9 37.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE28667.1 - 5.6e-10 38.0 23.6 7.5e-10 37.6 16.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_1 PF00232.13 EPE28668.1 - 3.8e-114 381.3 1.6 5.5e-114 380.8 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Activator_LAG-3 PF11498.3 EPE28669.1 - 0.029 13.1 13.1 0.038 12.7 9.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Lac_bphage_repr PF06543.7 EPE28669.1 - 0.086 12.3 0.2 0.2 11.1 0.2 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor Ycf1 PF05758.7 EPE28669.1 - 0.31 8.6 7.5 0.32 8.6 5.2 1.1 1 0 0 1 1 1 0 Ycf1 zinc-ribbons_6 PF07191.7 EPE28669.1 - 0.52 10.1 5.0 1.8 8.4 0.5 2.4 1 1 1 2 2 2 0 zinc-ribbons FAA_hydrolase_N PF09298.6 EPE28669.1 - 0.74 9.8 6.2 0.59 10.1 3.3 1.6 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal zinc_ribbon_5 PF13719.1 EPE28669.1 - 1.7 8.3 10.3 1.8 8.2 0.1 3.4 2 1 1 3 3 3 0 zinc-ribbon domain Neur_chan_memb PF02932.11 EPE28669.1 - 2 8.2 3.6 2.5 7.9 2.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EutA PF06277.6 EPE28669.1 - 2.4 6.6 4.3 3.3 6.1 3.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA DUF2229 PF09989.4 EPE28669.1 - 2.4 7.5 6.3 3.5 7.0 4.3 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Hom_end_hint PF05203.11 EPE28669.1 - 2.5 7.7 6.8 3.5 7.3 4.7 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint APG6 PF04111.7 EPE28669.1 - 3.3 6.6 16.8 4.7 6.1 11.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 BORG_CEP PF14957.1 EPE28669.1 - 4.4 8.2 7.3 8.4 7.3 5.1 1.5 1 0 0 1 1 1 0 Cdc42 effector zinc_ribbon_4 PF13717.1 EPE28669.1 - 6.1 6.6 10.9 6.3 6.5 0.2 3.4 2 1 1 3 3 3 0 zinc-ribbon domain Spore_coat_CotO PF14153.1 EPE28669.1 - 8.3 5.8 18.4 12 5.3 12.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DnaJ PF00226.26 EPE28670.1 - 2e-18 65.8 1.2 3.7e-18 64.9 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3450 PF11932.3 EPE28670.1 - 0.011 15.0 0.6 0.012 14.8 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.5 EPE28670.1 - 0.05 13.7 0.3 0.1 12.7 0.1 1.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tyrosinase PF00264.15 EPE28671.1 - 1.1e-42 146.7 0.0 1.8e-42 146.0 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Eno-Rase_FAD_bd PF07055.7 EPE28671.1 - 0.073 13.0 0.1 0.23 11.4 0.1 1.7 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain DEAD PF00270.24 EPE28672.1 - 2.2e-18 66.3 0.0 4.4e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE28672.1 - 1.1e-08 34.7 0.6 4.6e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE28672.1 - 2.6e-08 33.9 0.0 4e-07 30.0 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EPE28672.1 - 0.011 14.9 0.0 0.035 13.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Fungal_trans_2 PF11951.3 EPE28673.1 - 9.5e-12 44.1 1.7 2e-11 43.1 1.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain E1-E2_ATPase PF00122.15 EPE28674.1 - 4.8e-67 225.3 3.2 1.1e-66 224.2 2.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPE28674.1 - 4.6e-34 117.5 2.9 4.6e-34 117.5 2.0 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPE28674.1 - 2.9e-28 99.7 0.2 2.6e-23 83.5 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPE28674.1 - 2.4e-22 78.6 0.0 8e-22 77.0 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EPE28674.1 - 1.1e-14 53.5 0.0 3.1e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EPE28674.1 - 5.7e-12 46.1 0.1 1.7e-11 44.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPE28674.1 - 6.8e-07 29.1 0.9 0.0098 15.4 0.8 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase FSH1 PF03959.8 EPE28676.1 - 4.5e-31 107.9 0.0 5.7e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EPE28676.1 - 0.0029 17.5 0.1 0.021 14.6 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE28676.1 - 0.0061 16.3 0.0 0.012 15.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE28676.1 - 0.077 12.4 0.0 4.2 6.7 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Transferase PF02458.10 EPE28677.1 - 1.1e-23 83.3 0.0 5.4e-22 77.8 0.0 2.0 2 0 0 2 2 2 2 Transferase family FAD_binding_3 PF01494.14 EPE28678.1 - 1.9e-15 56.8 3.1 3.6e-12 46.0 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EPE28678.1 - 1.2e-06 28.4 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 EPE28678.1 - 1.4e-05 24.2 0.2 6e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE28678.1 - 4.9e-05 23.2 0.5 0.00028 20.8 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPE28678.1 - 0.0033 17.5 0.0 0.011 15.7 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE28678.1 - 0.0034 17.7 0.6 0.0085 16.4 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE28678.1 - 0.0094 15.8 0.2 0.017 15.0 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE28678.1 - 0.014 14.3 0.1 0.39 9.5 0.1 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPE28678.1 - 0.017 13.9 0.5 0.028 13.2 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain SE PF08491.5 EPE28678.1 - 0.076 11.8 0.0 0.48 9.2 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.9 EPE28678.1 - 0.08 11.4 0.4 0.11 10.9 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_4 PF01565.18 EPE28679.1 - 8.3e-20 70.6 2.2 1.4e-19 69.9 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE28679.1 - 6e-08 32.4 0.1 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Zn_clus PF00172.13 EPE28680.1 - 0.014 15.3 12.2 0.026 14.4 8.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 EPE28681.1 - 1.9e-67 227.4 1.2 1e-66 225.0 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EPE28681.1 - 1e-31 109.2 0.0 2.5e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EPE28681.1 - 8e-30 103.5 0.0 1.4e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 EPE28681.1 - 7.7e-26 91.1 0.1 1.5e-23 83.6 0.0 2.5 2 0 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.20 EPE28681.1 - 7.4e-22 77.3 5.4 1.1e-11 44.8 0.1 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EPE28681.1 - 1.7e-15 57.2 0.0 5.3e-15 55.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.1 EPE28681.1 - 1.2e-10 41.0 0.0 2.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_31 PF13847.1 EPE28681.1 - 4.2e-08 32.9 0.0 1.3e-07 31.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE28681.1 - 2e-06 27.6 0.0 7.3e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE28681.1 - 6.6e-06 26.5 0.0 2e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE28681.1 - 5.9e-05 23.6 0.0 0.00039 20.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.20 EPE28681.1 - 0.00012 21.9 0.0 0.00036 20.4 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.18 EPE28681.1 - 0.0012 17.8 0.2 0.0031 16.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.16 EPE28681.1 - 0.0019 17.7 0.0 0.0051 16.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EPE28681.1 - 0.0061 16.2 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 KR domain Methyltransf_26 PF13659.1 EPE28681.1 - 0.008 16.1 0.0 0.025 14.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EPE28681.1 - 0.024 13.6 0.0 0.057 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Sigma70_ner PF04546.8 EPE28681.1 - 2.1 7.8 4.2 5.4 6.5 0.8 2.7 3 0 0 3 3 3 0 Sigma-70, non-essential region ADH_N PF08240.7 EPE28682.1 - 5e-09 35.8 0.0 5e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE28682.1 - 2.1e-07 30.5 0.0 4.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EPE28683.1 - 7e-20 71.9 0.0 6.7e-19 68.7 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE28683.1 - 9.2e-18 63.7 0.0 3.7e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPE28683.1 - 1.2e-08 34.2 0.0 7.6e-08 31.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EPE28683.1 - 1.1e-07 31.8 0.0 9.5e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPE28683.1 - 0.00032 19.8 0.0 0.0031 16.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EPE28683.1 - 0.00054 19.9 0.0 0.0025 17.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE28683.1 - 0.00079 19.7 0.1 1.8 9.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE28683.1 - 0.0033 16.3 0.0 0.093 11.6 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EPE28683.1 - 0.093 11.5 0.1 4.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.11 EPE28684.1 - 1.6e-40 138.9 48.4 1.6e-40 138.9 33.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE28684.1 - 1e-11 43.8 24.2 1.4e-11 43.3 16.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE28684.1 - 2.4e-07 29.7 14.1 2.4e-07 29.7 9.8 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE28685.1 - 9.6e-33 113.3 56.1 1.4e-32 112.8 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE28685.1 - 2.4e-11 42.9 20.7 2.4e-11 42.9 14.3 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter FAD_binding_4 PF01565.18 EPE28686.1 - 9.4e-28 96.4 1.7 9.4e-28 96.4 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPE28686.1 - 1.2e-06 28.3 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans PF04082.13 EPE28687.1 - 6.7e-16 57.9 4.7 1.2e-15 57.1 3.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE28687.1 - 9.7e-10 38.2 7.2 1.8e-09 37.3 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AnfG_VnfG PF03139.10 EPE28687.1 - 0.014 15.2 0.9 6 6.7 0.0 2.7 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit UPF0565 PF10561.4 EPE28688.1 - 0.12 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 tRNA-synt_2c PF01411.14 EPE28690.1 - 1.1e-09 37.1 0.0 1.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EPE28690.1 - 0.0029 17.4 1.1 0.0053 16.6 0.8 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain YL1 PF05764.8 EPE28691.1 - 2.1 7.9 8.5 0.17 11.4 1.5 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Fungal_trans_2 PF11951.3 EPE28692.1 - 2.1e-15 56.2 0.3 4.7e-15 55.0 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Epiglycanin_C PF14654.1 EPE28693.1 - 0.028 14.4 0.3 0.11 12.5 0.2 2.0 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Elf1 PF05129.8 EPE28694.1 - 0.015 14.9 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-CHY PF05495.7 EPE28694.1 - 0.051 13.7 0.1 0.071 13.2 0.1 1.3 1 0 0 1 1 1 0 CHY zinc finger HET PF06985.6 EPE28695.1 - 2.8e-37 127.9 0.1 8.2e-37 126.4 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AP_endonuc_2 PF01261.19 EPE28695.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Bac_luciferase PF00296.15 EPE28696.1 - 4.5e-62 209.9 0.1 5.8e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase p450 PF00067.17 EPE28698.1 - 7.2e-43 146.7 0.0 3.4e-42 144.5 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Wzy_C PF04932.10 EPE28698.1 - 0.0087 15.8 0.1 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 O-Antigen ligase p450 PF00067.17 EPE28699.1 - 5.2e-31 107.6 0.0 8.7e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 PP-binding PF00550.20 EPE28700.1 - 1.3e-08 34.9 0.1 2.5e-08 34.0 0.0 1.6 1 1 1 2 2 2 1 Phosphopantetheine attachment site ketoacyl-synt PF00109.21 EPE28701.1 - 2.1e-57 194.5 0.0 3.5e-57 193.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EPE28701.1 - 6.5e-50 169.9 0.0 1.1e-49 169.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EPE28701.1 - 4.6e-49 167.4 2.7 1.7e-47 162.2 0.3 2.7 2 1 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EPE28701.1 - 1.7e-23 82.6 0.6 7e-22 77.4 0.4 2.4 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EPE28701.1 - 5.7e-18 65.2 0.0 1.4e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE28701.1 - 1.7e-11 44.0 0.0 3.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE28701.1 - 7.3e-10 38.6 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE28701.1 - 1.6e-08 34.9 0.0 5.2e-08 33.2 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE28701.1 - 4.8e-08 33.5 0.0 1.6e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE28701.1 - 3.5e-05 24.1 0.0 9.5e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE28701.1 - 0.00024 20.3 0.0 0.00043 19.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EPE28701.1 - 0.00082 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EPE28701.1 - 0.0011 18.0 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 EPE28701.1 - 0.0053 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 EPE28701.1 - 0.0059 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 EPE28701.1 - 0.009 15.4 0.0 0.039 13.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Thiolase_N PF00108.18 EPE28701.1 - 0.014 14.4 0.1 0.026 13.5 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain PCMT PF01135.14 EPE28701.1 - 0.096 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.7 EPE28701.1 - 0.16 10.8 0.0 0.32 9.8 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Abhydrolase_3 PF07859.8 EPE28702.1 - 7.1e-10 38.8 0.1 1.7e-09 37.5 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE28702.1 - 4.8e-09 36.1 0.0 7.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE28702.1 - 3.7e-07 30.2 1.0 5.9e-07 29.5 0.7 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EPE28702.1 - 0.0004 19.3 0.0 0.00068 18.6 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EPE28702.1 - 0.0005 19.3 0.0 0.021 14.0 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 EPE28702.1 - 0.00071 18.4 0.1 0.0087 14.8 0.0 2.2 3 0 0 3 3 3 1 Carboxylesterase family Chlorophyllase PF07224.6 EPE28702.1 - 0.0066 15.2 0.0 0.009 14.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.11 EPE28702.1 - 0.0071 15.8 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ribonuclease_T2 PF00445.13 EPE28703.1 - 2.4e-39 134.8 0.1 3.5e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family SNO PF01174.14 EPE28704.1 - 1.5e-50 171.4 0.0 1.2e-40 139.1 0.0 2.1 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EPE28704.1 - 2.1e-08 33.9 0.0 5.4e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 EPE28704.1 - 8.8e-06 25.2 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EPE28704.1 - 1.8e-05 24.2 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Acyltransferase PF01553.16 EPE28705.1 - 2.9e-33 114.0 0.0 5e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.16 EPE28705.1 - 0.079 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP AAA PF00004.24 EPE28706.1 - 7.1e-18 65.0 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE28706.1 - 0.002 18.1 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EPE28706.1 - 0.0025 18.6 0.5 0.03 15.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE28706.1 - 0.0042 17.2 0.1 0.1 12.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EPE28706.1 - 0.0059 16.3 0.0 0.025 14.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Torsin PF06309.6 EPE28706.1 - 0.0093 15.8 0.1 0.16 11.8 0.0 2.3 2 0 0 2 2 2 1 Torsin AAA_33 PF13671.1 EPE28706.1 - 0.014 15.2 0.0 0.043 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Statherin PF03875.8 EPE28706.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Statherin AAA_14 PF13173.1 EPE28706.1 - 0.085 12.7 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Clr5 PF14420.1 EPE28707.1 - 3.3e-16 58.8 3.5 7.7e-16 57.7 2.4 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 EPE28707.1 - 2.9e-09 36.7 1.8 1.5e-05 24.8 0.0 3.6 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 EPE28707.1 - 0.007 16.3 0.9 0.018 14.9 0.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE28707.1 - 0.043 13.6 0.0 0.45 10.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPE28707.1 - 0.068 13.1 0.0 0.53 10.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Zn_clus PF00172.13 EPE28709.1 - 0.00036 20.3 12.3 0.00076 19.3 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EPE28709.1 - 0.026 14.8 0.0 0.026 14.8 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger PHO4 PF01384.15 EPE28710.1 - 7.1e-98 327.2 20.9 8.3e-98 327.0 14.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF1084 PF06454.6 EPE28710.1 - 0.0093 15.0 0.7 0.29 10.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1084) FAD_binding_3 PF01494.14 EPE28711.1 - 1.4e-16 60.5 0.0 7.4e-13 48.2 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EPE28711.1 - 6.3e-08 31.9 0.1 0.0055 15.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPE28711.1 - 3.8e-06 27.1 0.4 3.1e-05 24.1 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE28711.1 - 0.0018 18.2 0.3 0.0045 16.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE28711.1 - 0.0019 17.1 0.0 0.45 9.3 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.19 EPE28711.1 - 0.0019 17.3 0.1 0.19 10.7 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EPE28711.1 - 0.0074 16.0 0.1 2.3 7.9 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 EPE28711.1 - 0.0093 14.8 0.0 0.45 9.2 0.0 2.4 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.12 EPE28711.1 - 0.012 14.7 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EPE28711.1 - 0.016 13.7 0.0 1.7 7.0 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 EPE28711.1 - 0.016 15.0 0.0 0.064 13.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE28711.1 - 0.02 15.2 0.0 3.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EPE28711.1 - 0.035 13.7 0.3 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YCII PF03795.9 EPE28712.1 - 0.036 14.2 0.0 0.061 13.5 0.0 1.4 1 1 0 1 1 1 0 YCII-related domain NUDIX_4 PF14815.1 EPE28712.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 NUDIX domain Tim17 PF02466.14 EPE28715.1 - 5.3e-27 94.3 3.5 7e-27 94.0 2.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.4 EPE28716.1 - 2.2e-56 190.7 6.1 4.8e-55 186.3 2.8 2.7 2 0 0 2 2 2 2 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EPE28716.1 - 5.3e-13 47.8 6.1 0.0041 17.0 0.0 6.9 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EPE28716.1 - 1.5e-05 25.2 10.9 0.042 14.1 0.5 6.3 6 1 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 EPE28716.1 - 0.00041 20.7 5.4 2.7 8.5 0.0 6.3 5 1 1 6 6 6 1 HEAT-like repeat DUF4030 PF13222.1 EPE28716.1 - 0.084 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) TadE PF07811.7 EPE28717.1 - 0.038 13.8 0.7 0.066 13.1 0.5 1.4 1 0 0 1 1 1 0 TadE-like protein TraL PF07178.6 EPE28717.1 - 0.07 13.1 0.1 0.079 12.9 0.1 1.1 1 0 0 1 1 1 0 TraL protein Cytochrom_B561 PF03188.11 EPE28717.1 - 0.074 12.8 0.3 0.092 12.5 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 NVEALA PF14055.1 EPE28717.1 - 0.21 11.3 0.8 0.26 11.0 0.6 1.2 1 0 0 1 1 1 0 NVEALA protein DUF3487 PF11990.3 EPE28719.1 - 0.019 14.3 1.4 0.032 13.6 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3487) Cytochrom_B_N PF00033.14 EPE28719.1 - 0.057 12.7 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF2207 PF09972.4 EPE28719.1 - 0.062 11.8 0.0 0.062 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ni_hydr_CYTB PF01292.15 EPE28719.1 - 0.064 12.6 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 UPF0233 PF06781.7 EPE28719.1 - 0.073 12.6 1.4 0.11 12.1 0.7 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) Myc_target_1 PF15179.1 EPE28719.1 - 0.13 11.8 0.6 0.24 10.9 0.4 1.4 1 0 0 1 1 1 0 Myc target protein 1 PX PF00787.19 EPE28721.1 - 2.2e-19 69.3 0.0 6.4e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EPE28721.1 - 1.7e-13 50.3 4.5 1.5e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 Vps5 C terminal like ATP-synt_E PF05680.7 EPE28721.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.3 2 0 0 2 2 2 0 ATP synthase E chain Pex14_N PF04695.8 EPE28721.1 - 3.4 7.7 6.7 4.1 7.4 0.2 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mito_carr PF00153.22 EPE28722.1 - 5.3e-47 157.4 0.1 2e-15 56.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 EPE28722.1 - 0.033 14.5 2.6 11 6.4 0.0 3.8 4 1 0 4 4 4 0 YtxH-like protein zf-C3HC4_2 PF13923.1 EPE28723.1 - 3.7e-09 36.4 12.3 3.5e-05 23.7 2.3 2.9 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE28723.1 - 1.4e-07 31.2 11.1 2.2e-05 24.1 2.5 2.7 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 EPE28723.1 - 1.9e-06 27.4 12.8 3.7e-05 23.2 3.0 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE28723.1 - 4.6e-06 26.2 4.8 4.6e-06 26.2 3.3 2.9 2 2 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.7 EPE28723.1 - 1.6e-05 24.2 2.4 1.6e-05 24.2 1.7 2.9 1 1 2 3 3 3 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 EPE28723.1 - 0.0001 21.8 13.8 0.00034 20.1 1.0 2.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EPE28723.1 - 0.00037 20.3 7.3 0.0021 17.9 1.3 2.6 2 0 0 2 2 2 1 FYVE zinc finger zf-RING_UBOX PF13445.1 EPE28723.1 - 0.0024 17.5 2.1 0.0024 17.5 1.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EPE28723.1 - 0.048 13.2 0.5 0.048 13.2 0.4 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EPE28723.1 - 0.1 12.5 14.7 1.7 8.5 1.3 3.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Acyltransferase PF01553.16 EPE28724.1 - 5.2e-13 48.5 0.0 1.7e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 Acyltransferase Abhydrolase_5 PF12695.2 EPE28728.1 - 3.3e-17 62.5 0.0 4.3e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE28728.1 - 3.2e-09 37.0 0.1 7.8e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE28728.1 - 4.6e-06 25.9 0.1 0.012 14.8 0.1 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 EPE28728.1 - 0.00015 21.1 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EPE28728.1 - 0.00032 20.3 0.0 0.00065 19.3 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold VirJ PF06057.6 EPE28728.1 - 0.0031 17.3 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.11 EPE28728.1 - 0.0056 16.1 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF915 PF06028.6 EPE28728.1 - 0.008 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) PhoPQ_related PF10142.4 EPE28728.1 - 0.0083 14.6 0.1 0.017 13.6 0.1 1.4 2 0 0 2 2 2 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_7 PF12715.2 EPE28728.1 - 0.083 11.8 0.2 12 4.7 0.0 2.5 2 1 1 3 3 3 0 Abhydrolase family MFS_1 PF07690.11 EPE28729.1 - 8.1e-37 126.7 46.3 1.7e-35 122.4 22.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.18 EPE28730.1 - 8.7e-11 41.8 18.0 4.4e-10 39.5 12.5 1.9 1 1 0 1 1 1 1 Membrane-associating domain Shisa PF13908.1 EPE28730.1 - 0.0057 16.8 0.6 0.0089 16.2 0.4 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Hum_adeno_E3A PF05393.6 EPE28730.1 - 0.19 11.4 1.7 3 7.5 0.2 2.2 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein PHA-1 PF06542.6 EPE28731.1 - 0.091 11.4 0.3 0.13 10.9 0.2 1.1 1 0 0 1 1 1 0 Regulator protein PHA-1 PDR_assoc PF08370.6 EPE28731.1 - 7.9 6.0 10.6 3.1 7.3 0.0 3.2 3 0 0 3 3 3 0 Plant PDR ABC transporter associated ILVD_EDD PF00920.16 EPE28733.1 - 8.4e-205 681.1 0.5 9.7e-205 680.9 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.13 EPE28733.1 - 0.0063 16.5 0.0 0.06 13.3 0.0 2.6 3 0 0 3 3 3 1 5'-nucleotidase, C-terminal domain Peptidase_M14 PF00246.19 EPE28734.1 - 2.9e-40 138.6 0.4 4.2e-40 138.1 0.3 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase C1_1 PF00130.17 EPE28735.1 - 0.0046 16.6 0.6 0.011 15.4 0.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-GRF PF06839.7 EPE28735.1 - 0.0073 16.2 5.7 0.074 12.9 0.3 2.8 2 1 0 2 2 2 2 GRF zinc finger Collagen PF01391.13 EPE28737.1 - 0.0029 17.1 6.5 0.0068 15.9 4.5 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) U79_P34 PF03064.11 EPE28737.1 - 1.3 8.4 20.5 1.8 8.0 14.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Glyco_hydro_12 PF01670.11 EPE28738.1 - 8.6e-39 132.8 0.8 1.5e-38 132.0 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Ecl1 PF12855.2 EPE28739.1 - 5.7e-06 25.5 0.8 1e-05 24.7 0.5 1.3 1 0 0 1 1 1 1 Life-span regulatory factor BTB PF00651.26 EPE28740.1 - 3.3e-08 33.4 0.2 0.00014 21.8 0.0 2.9 2 1 1 3 3 3 2 BTB/POZ domain CytochromB561_N PF09786.4 EPE28740.1 - 0.29 9.5 2.5 0.36 9.2 1.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal PSP94 PF05825.6 EPE28742.1 - 0.52 10.6 3.6 7.2 6.9 1.4 2.3 2 1 0 2 2 2 0 Beta-microseminoprotein (PSP-94) 2OG-FeII_Oxy PF03171.15 EPE28744.1 - 1.9e-05 24.8 0.0 5.6e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EPE28744.1 - 3.2e-05 24.3 0.0 5.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MRP-S26 PF14943.1 EPE28746.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 HET PF06985.6 EPE28747.1 - 2.4e-05 24.5 0.0 4.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2855 PF11017.3 EPE28748.1 - 3.3e-72 243.2 0.0 3.9e-72 243.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) mRNA_cap_enzyme PF01331.14 EPE28749.1 - 2.2e-50 171.0 0.1 3e-50 170.6 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EPE28749.1 - 2.1e-23 82.6 0.2 5e-23 81.4 0.1 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EPE28749.1 - 1.5e-07 31.0 0.1 1.6e-05 24.3 0.0 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DUF3958 PF13125.1 EPE28749.1 - 0.085 12.7 2.1 0.087 12.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) DUF1762 PF08574.5 EPE28751.1 - 5.9e-07 29.8 10.9 5.9e-07 29.8 7.5 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1762) ABC2_membrane PF01061.19 EPE28752.1 - 3e-91 304.2 40.7 3e-48 163.7 11.6 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EPE28752.1 - 2.9e-41 140.9 0.0 6.7e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EPE28752.1 - 1.6e-30 104.8 5.0 2.5e-28 97.7 0.0 3.4 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 EPE28752.1 - 2.6e-16 59.5 27.9 2e-11 43.5 8.2 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EPE28752.1 - 7.1e-09 35.6 0.0 2e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EPE28752.1 - 3.6e-07 29.7 0.0 0.00058 19.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPE28752.1 - 7.7e-06 26.0 0.2 0.05 13.7 0.0 3.1 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 EPE28752.1 - 0.00018 20.7 0.1 0.0015 17.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EPE28752.1 - 0.0002 20.8 0.7 0.37 10.2 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EPE28752.1 - 0.00031 21.0 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPE28752.1 - 0.00032 20.7 0.3 0.062 13.2 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EPE28752.1 - 0.00069 19.6 0.0 0.29 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EPE28752.1 - 0.00099 19.1 0.3 1.3 8.9 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EPE28752.1 - 0.0014 18.1 1.4 0.06 12.8 0.1 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EPE28752.1 - 0.0023 17.6 0.4 1.2 8.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EPE28752.1 - 0.0025 18.6 0.0 1.5 9.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPE28752.1 - 0.01 15.7 0.1 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EPE28752.1 - 0.021 14.2 0.4 1.6 8.1 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EPE28752.1 - 0.023 14.3 0.7 2.6 7.7 0.2 2.4 2 0 0 2 2 2 0 NACHT domain RuvB_N PF05496.7 EPE28752.1 - 0.044 12.8 0.1 0.69 8.9 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Miro PF08477.8 EPE28752.1 - 0.062 13.8 0.0 3.5 8.1 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 EPE28752.1 - 0.064 13.4 0.0 13 5.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EPE28752.1 - 0.073 12.7 0.1 16 5.1 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase UPF0079 PF02367.12 EPE28752.1 - 0.089 12.4 0.7 4.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EPE28752.1 - 0.38 10.2 0.6 8.5 5.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain Glyco_hydro_6 PF01341.12 EPE28753.1 - 3.3e-96 322.2 2.0 4.2e-96 321.9 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 zf-MYND PF01753.13 EPE28755.1 - 1e-08 34.9 6.1 1.8e-08 34.1 4.3 1.4 1 0 0 1 1 1 1 MYND finger DUF106 PF01956.11 EPE28755.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 zf-Mss51 PF13824.1 EPE28755.1 - 0.25 11.2 1.8 0.48 10.3 1.2 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF4360 PF14273.1 EPE28756.1 - 4.5e-61 205.6 3.0 5.2e-61 205.4 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Abhydrolase_6 PF12697.2 EPE28757.1 - 1.1e-22 81.1 0.9 1.3e-22 80.7 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE28757.1 - 6.2e-11 42.2 0.2 1.1e-10 41.4 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE28757.1 - 2.8e-10 40.1 0.0 3.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE28757.1 - 2.6e-05 23.9 0.0 6.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Fungal_trans PF04082.13 EPE28758.1 - 3.1e-18 65.5 0.1 6.4e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE28758.1 - 2.3e-08 33.8 11.9 4e-08 33.0 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE28759.1 - 4.9e-15 55.1 0.0 1.1e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_1 PF00190.17 EPE28760.1 - 9.9e-29 99.6 0.0 6.6e-15 54.8 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EPE28760.1 - 1.6e-23 81.9 0.7 1.5e-10 40.4 0.0 3.0 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.7 EPE28760.1 - 7.7e-11 41.2 0.1 4.8e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 EPE28760.1 - 4.9e-08 32.7 0.0 3.5e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase FdtA PF05523.6 EPE28760.1 - 4.7e-07 29.3 0.0 0.025 14.0 0.0 2.2 2 0 0 2 2 2 2 WxcM-like, C-terminal AraC_binding PF02311.14 EPE28760.1 - 1.1e-05 25.0 0.0 6.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain 3-HAO PF06052.7 EPE28760.1 - 0.0086 15.4 0.0 0.031 13.6 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_8 PF13621.1 EPE28760.1 - 0.012 15.1 0.0 0.16 11.4 0.0 2.3 2 1 0 2 2 2 0 Cupin-like domain Cupin_4 PF08007.7 EPE28760.1 - 0.013 14.7 0.0 0.28 10.4 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein ARD PF03079.9 EPE28760.1 - 0.02 14.8 0.1 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family Cupin_6 PF12852.2 EPE28760.1 - 0.022 14.3 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Cupin 2OG-FeII_Oxy_5 PF13759.1 EPE28760.1 - 0.079 13.2 0.2 4.6 7.6 0.0 3.2 3 1 1 4 4 4 0 Putative 2OG-Fe(II) oxygenase Zn_clus PF00172.13 EPE28761.1 - 1.4e-06 28.0 9.6 3.4e-06 26.8 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Act-Frag_cataly PF09192.5 EPE28764.1 - 0.016 14.1 0.3 0.046 12.7 0.1 2.0 2 0 0 2 2 2 0 Actin-fragmin kinase, catalytic Fungal_trans PF04082.13 EPE28765.1 - 5.5e-17 61.5 0.2 8.8e-17 60.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_UL92 PF03048.9 EPE28768.1 - 0.0024 17.4 0.4 0.0047 16.5 0.0 1.7 2 0 0 2 2 2 1 UL92 family AIF_C PF14721.1 EPE28768.1 - 0.033 14.4 0.0 0.075 13.2 0.0 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Late_protein_L2 PF00513.13 EPE28768.1 - 0.14 10.9 11.1 0.28 10.0 7.7 1.5 1 0 0 1 1 1 0 Late Protein L2 Podoplanin PF05808.6 EPE28768.1 - 0.84 9.1 19.3 0.021 14.3 8.0 1.9 1 1 1 2 2 2 0 Podoplanin Macoilin PF09726.4 EPE28768.1 - 4.6 5.4 7.7 6.4 4.9 5.3 1.2 1 0 0 1 1 1 0 Transmembrane protein MutL PF13941.1 EPE28769.1 - 0.081 11.2 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 MutL protein DUF3592 PF12158.3 EPE28770.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) NicO PF03824.11 EPE28771.1 - 2.8e-55 187.6 13.8 2.8e-55 187.6 9.5 1.4 2 0 0 2 2 2 1 High-affinity nickel-transport protein COX4_pro_2 PF07835.7 EPE28771.1 - 1.4 8.9 0.0 1.4 8.9 0.0 3.4 4 0 0 4 4 4 0 Bacterial aa3 type cytochrome c oxidase subunit IV Histone PF00125.19 EPE28773.1 - 0.1 12.7 0.2 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Abhydrolase_6 PF12697.2 EPE28774.1 - 7.9e-30 104.4 0.0 1.3e-29 103.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE28774.1 - 4.6e-20 72.1 0.0 2.7e-18 66.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE28774.1 - 4.4e-14 52.4 0.0 1.4e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE28774.1 - 0.00024 20.9 0.0 0.0004 20.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EPE28774.1 - 0.048 12.8 0.0 0.6 9.2 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family Ndr PF03096.9 EPE28774.1 - 0.11 10.9 0.0 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family Pinin_SDK_memA PF04696.8 EPE28775.1 - 1.9e-25 88.9 13.7 1.9e-25 88.9 9.5 2.3 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region PHF5 PF03660.9 EPE28776.1 - 2.1e-51 172.4 10.0 2.4e-51 172.2 7.0 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EPE28776.1 - 0.92 9.3 15.7 0.19 11.5 5.4 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EPE28776.1 - 1.4 8.7 15.8 2.9 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 EPE28776.1 - 6 6.6 15.3 0.2 11.3 4.5 2.5 1 1 1 2 2 2 0 PHD-finger Peptidase_M24 PF00557.19 EPE28777.1 - 2.3e-12 46.9 0.0 3.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 NusA_N PF08529.6 EPE28777.1 - 0.18 11.8 2.4 0.35 10.8 0.8 2.1 2 0 0 2 2 2 0 NusA N-terminal domain SNF5 PF04855.7 EPE28778.1 - 3.4e-71 239.5 0.0 5.4e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 CytochromB561_N PF09786.4 EPE28778.1 - 0.25 9.7 0.3 0.37 9.1 0.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF1793 PF08760.6 EPE28779.1 - 1.8e-36 125.5 6.0 1.7e-24 86.5 0.2 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 EPE28779.1 - 0.0012 17.1 0.2 0.0023 16.2 0.2 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase MOSC PF03473.12 EPE28780.1 - 1e-20 73.5 0.1 4.9e-20 71.3 0.0 2.2 3 0 0 3 3 3 1 MOSC domain Fer2 PF00111.22 EPE28780.1 - 5.8e-10 38.7 1.9 1.2e-09 37.8 1.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 EPE28780.1 - 1.9e-05 25.2 0.0 0.00016 22.2 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain CART PF06373.6 EPE28780.1 - 0.1 12.5 1.4 0.31 11.0 1.0 1.8 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) Ank_2 PF12796.2 EPE28782.1 - 4.6e-26 90.9 0.0 3.6e-09 36.8 0.0 4.3 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPE28782.1 - 1.2e-17 62.2 0.0 1.2e-05 25.0 0.0 7.1 6 1 1 7 7 7 3 Ankyrin repeat Ank PF00023.25 EPE28782.1 - 1.8e-17 62.1 0.3 2.2e-06 27.1 0.0 7.2 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.1 EPE28782.1 - 4.9e-14 52.0 0.9 0.00034 20.7 0.0 5.9 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE28782.1 - 2.9e-10 40.3 0.2 0.0014 19.0 0.0 5.5 6 1 0 6 6 6 2 Ankyrin repeats (many copies) RNase_H PF00075.19 EPE28784.1 - 3.1e-06 27.5 0.0 6.8e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 RNase H SnoaL PF07366.7 EPE28785.1 - 5.8e-23 80.8 0.0 6.6e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EPE28785.1 - 3.8e-11 43.3 0.1 5.3e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain GH114_assoc PF14741.1 EPE28785.1 - 0.067 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain HEAT_2 PF13646.1 EPE28786.1 - 3.6e-06 27.1 2.0 0.0015 18.8 0.1 4.5 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EPE28786.1 - 3.3e-05 23.6 8.0 0.39 10.9 0.0 5.5 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EPE28786.1 - 0.00018 21.8 6.6 0.065 13.7 0.1 4.7 4 0 0 4 4 4 2 HEAT-like repeat Pec_lyase_N PF04431.8 EPE28786.1 - 0.027 14.5 0.2 0.7 10.0 0.1 2.6 2 0 0 2 2 2 0 Pectate lyase, N terminus Cu-oxidase_3 PF07732.10 EPE28788.1 - 3.1e-40 136.5 3.8 3.1e-40 136.5 2.6 3.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPE28788.1 - 2.4e-39 133.9 6.9 1e-36 125.4 0.4 4.1 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EPE28788.1 - 6.5e-33 113.8 0.4 2.5e-32 111.9 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Ank_2 PF12796.2 EPE28790.1 - 4.2e-19 68.6 0.0 1.8e-13 50.6 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE28790.1 - 1.2e-15 56.3 0.1 1.9e-05 24.2 0.0 5.1 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EPE28790.1 - 1.2e-13 49.8 0.0 0.00022 21.1 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EPE28790.1 - 1.7e-12 47.4 0.0 0.014 15.8 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE28790.1 - 0.00016 21.7 0.1 0.016 15.4 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF3159 PF11361.3 EPE28792.1 - 0.04 13.3 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) AA_permease PF00324.16 EPE28793.1 - 1.6e-121 406.0 44.3 1.8e-121 405.8 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE28793.1 - 1e-34 119.7 49.5 1.3e-34 119.4 34.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3370 PF11850.3 EPE28795.1 - 0.18 10.2 0.5 0.27 9.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) Glyco_hydro_28 PF00295.12 EPE28796.1 - 4e-47 160.7 1.8 5.2e-47 160.3 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ET PF01684.11 EPE28796.1 - 0.047 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 ET module YabP PF07873.6 EPE28796.1 - 0.17 11.4 0.4 0.44 10.1 0.1 1.8 2 0 0 2 2 2 0 YabP family Tyrosinase PF00264.15 EPE28797.1 - 1.8e-53 181.9 4.7 1.8e-53 181.9 3.3 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase WAC_Acf1_DNA_bd PF10537.4 EPE28798.1 - 1.7e-38 130.8 0.5 5.1e-38 129.3 0.1 2.1 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EPE28798.1 - 3.4e-17 61.9 4.0 5.5e-17 61.2 2.8 1.3 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EPE28798.1 - 3e-13 49.0 0.5 7.4e-13 47.8 0.3 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EPE28798.1 - 0.0056 16.4 0.2 0.015 15.1 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 DUF303 PF03629.13 EPE28798.1 - 0.015 14.5 0.5 0.035 13.3 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF303) WHIM1 PF15612.1 EPE28798.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 IncA PF04156.9 EPE28798.1 - 0.95 9.0 8.7 12 5.3 3.7 2.8 2 0 0 2 2 2 0 IncA protein Alg6_Alg8 PF03155.10 EPE28799.1 - 4.7e-68 230.1 9.2 5.9e-68 229.8 6.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF2029 PF09594.5 EPE28799.1 - 0.0028 17.2 6.7 0.0028 17.2 4.6 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2029) Lectin_leg-like PF03388.8 EPE28800.1 - 8.3e-28 97.0 0.0 1.2e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family PRCC PF10253.4 EPE28800.1 - 0.024 15.3 1.8 0.035 14.8 1.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Phage_T7_Capsid PF05396.6 EPE28800.1 - 0.036 14.2 0.7 0.16 12.0 0.0 2.2 1 1 2 3 3 3 0 Phage T7 capsid assembly protein DUF2175 PF09943.4 EPE28801.1 - 0.52 10.3 3.5 1.2 9.2 2.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) CAF1 PF04857.15 EPE28802.1 - 5.2e-47 160.3 0.1 6.4e-47 160.0 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 EPE28802.1 - 0.00072 19.0 0.0 0.021 14.3 0.0 2.3 2 0 0 2 2 2 1 3'-5' exonuclease COesterase PF00135.23 EPE28804.1 - 1.5e-98 330.8 0.0 2e-98 330.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE28804.1 - 1.8e-05 24.4 0.1 6.2e-05 22.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_2 PF00891.13 EPE28805.1 - 4.8e-32 111.0 0.1 7.2e-32 110.4 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EPE28805.1 - 3.9e-06 26.6 0.5 7.5e-06 25.6 0.3 1.5 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.15 EPE28805.1 - 0.0037 17.3 0.1 0.0099 15.9 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulator Methyltransf_25 PF13649.1 EPE28805.1 - 0.021 15.1 0.2 0.35 11.2 0.1 2.5 1 1 0 1 1 1 0 Methyltransferase domain HTH_27 PF13463.1 EPE28805.1 - 0.11 12.8 0.1 19 5.6 0.0 2.6 1 1 1 2 2 2 0 Winged helix DNA-binding domain Arginase PF00491.16 EPE28806.1 - 3.7e-91 305.2 0.0 4.3e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EPE28806.1 - 0.065 13.4 0.1 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Cu_bind_like PF02298.12 EPE28807.1 - 0.0013 18.4 0.5 0.0069 16.1 0.4 2.1 1 1 0 1 1 1 1 Plastocyanin-like domain MRF_C2 PF13888.1 EPE28807.1 - 0.053 13.3 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 Cas_csx3 PF09620.5 EPE28807.1 - 0.071 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Cys_Met_Meta_PP PF01053.15 EPE28807.1 - 1.7 6.8 7.1 2.6 6.2 5.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Saccharop_dh PF03435.13 EPE28808.1 - 1.5e-20 73.5 0.0 2.9e-20 72.6 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EPE28808.1 - 0.013 15.8 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L37ae PF01780.14 EPE28809.1 - 1.1e-39 134.1 9.6 1.2e-39 134.0 6.7 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EPE28809.1 - 0.00066 19.4 2.9 0.001 18.8 2.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EPE28809.1 - 0.0022 17.3 5.1 0.011 15.1 0.1 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EPE28809.1 - 0.069 13.1 1.1 0.71 9.8 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Sgf11 PF08209.6 EPE28809.1 - 0.088 12.1 0.5 0.67 9.3 0.0 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) OrfB_Zn_ribbon PF07282.6 EPE28809.1 - 0.13 11.9 1.6 0.18 11.4 1.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain CarbpepA_inh PF02977.10 EPE28809.1 - 0.19 11.3 5.3 2.3 7.8 3.7 2.2 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-BED PF02892.10 EPE28809.1 - 0.28 10.9 7.6 2.7 7.8 0.9 2.4 1 1 1 2 2 2 0 BED zinc finger Elf1 PF05129.8 EPE28809.1 - 0.3 10.8 3.6 0.5 10.1 2.5 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.1 EPE28809.1 - 1 9.7 8.4 0.8 10.1 0.9 2.3 1 1 1 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 EPE28809.1 - 1.4 9.4 4.5 2.8 8.4 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type PHD PF00628.24 EPE28810.1 - 8.1e-11 41.4 5.5 8.1e-11 41.4 3.8 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EPE28810.1 - 2.6e-08 33.5 3.7 2.6e-08 33.5 2.6 3.9 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EPE28810.1 - 2.9e-07 30.5 2.5 2.9e-07 30.5 1.7 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EPE28810.1 - 7.3e-06 25.5 1.6 7.3e-06 25.5 1.1 3.5 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EPE28810.1 - 0.00011 21.3 2.8 0.00011 21.3 1.9 2.3 2 0 0 2 2 2 1 PHD-finger zf-Apc11 PF12861.2 EPE28810.1 - 0.00016 21.4 0.8 0.00016 21.4 0.5 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EPE28810.1 - 0.00021 21.2 3.4 0.00021 21.2 2.4 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EPE28810.1 - 0.00023 20.8 1.2 0.00023 20.8 0.9 2.9 3 1 0 3 3 3 1 Prokaryotic RING finger family 1 zf-RING_5 PF14634.1 EPE28810.1 - 0.0019 17.8 7.6 0.0019 17.8 5.2 3.5 2 2 1 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE28810.1 - 0.0041 16.7 6.9 0.0041 16.7 4.8 3.0 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EPE28810.1 - 0.0076 15.4 1.0 0.015 14.5 0.3 1.7 1 1 0 1 1 1 1 Rtf2 RING-finger DUF1653 PF07866.6 EPE28810.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1653) Prok-RING_4 PF14447.1 EPE28810.1 - 0.16 11.5 4.2 0.21 11.1 0.7 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EPE28810.1 - 0.42 10.3 6.7 0.042 13.5 0.7 2.3 2 0 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EPE28810.1 - 3 7.8 8.4 1.6 8.7 0.9 2.6 2 0 0 2 2 2 0 FANCL C-terminal domain MRP-L46 PF11788.3 EPE28811.1 - 1e-31 109.8 0.1 2.5e-31 108.5 0.0 1.7 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EPE28811.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain DAO PF01266.19 EPE28812.1 - 1.9e-20 73.0 5.5 2.4e-20 72.7 3.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FA_desaturase PF00487.19 EPE28813.1 - 1.9e-25 89.7 19.8 3.9e-25 88.7 13.7 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EPE28813.1 - 6.3e-05 23.0 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) adh_short PF00106.20 EPE28814.1 - 1.4e-11 44.5 0.0 2.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE28814.1 - 0.00013 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE28814.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EPE28814.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase LNS2 PF08235.8 EPE28814.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) NAD_binding_10 PF13460.1 EPE28814.1 - 0.078 12.9 0.0 0.42 10.5 0.0 2.1 1 1 0 1 1 1 0 NADH(P)-binding MFS_1 PF07690.11 EPE28815.1 - 1.9e-41 141.9 24.9 9.6e-39 133.0 8.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EPE28815.1 - 0.00048 18.3 6.7 0.00048 18.3 4.7 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector Mem_trans PF03547.13 EPE28815.1 - 0.0046 15.3 0.0 0.012 13.9 0.0 1.6 1 1 0 1 1 1 1 Membrane transport protein OATP PF03137.15 EPE28815.1 - 0.013 13.5 0.8 2.2 6.2 1.3 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PUF PF00806.14 EPE28816.1 - 1.6e-27 93.3 0.0 2.6e-05 23.4 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EPE28816.1 - 3.1e-10 39.5 0.0 6.2e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE28816.1 - 9.2e-06 25.5 0.0 2.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE28816.1 - 0.00025 20.8 0.0 0.0005 19.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2811 PF10929.3 EPE28816.1 - 0.079 12.9 0.1 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) YL1 PF05764.8 EPE28817.1 - 3.6e-54 183.9 24.3 3.6e-54 183.9 16.9 1.9 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EPE28817.1 - 1.3e-08 34.2 0.7 2.6e-08 33.2 0.5 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.11 EPE28817.1 - 0.0039 16.7 0.2 0.0065 16.0 0.1 1.2 1 0 0 1 1 1 1 HIT zinc finger DUF342 PF03961.8 EPE28817.1 - 1.9 6.7 8.8 3 6.1 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Methyltransf_31 PF13847.1 EPE28818.1 - 3.3e-31 107.9 0.0 5e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE28818.1 - 1.7e-19 70.1 0.0 4.2e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE28818.1 - 2.7e-15 56.9 0.0 5e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE28818.1 - 5.3e-15 55.1 0.0 7.9e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPE28818.1 - 1.4e-14 54.2 0.0 2.5e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE28818.1 - 8.3e-12 45.1 0.0 1.5e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE28818.1 - 1.2e-10 41.7 0.0 3e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE28818.1 - 3.6e-10 39.8 0.0 1.3e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EPE28818.1 - 5.7e-08 32.2 0.1 8.9e-08 31.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EPE28818.1 - 5.8e-08 32.5 0.0 1.1e-07 31.5 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EPE28818.1 - 2.5e-06 26.9 0.1 8.2e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 EPE28818.1 - 2.2e-05 23.6 0.0 3.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 EPE28818.1 - 0.0009 18.8 0.4 0.0024 17.4 0.3 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 EPE28818.1 - 0.0018 17.9 0.0 0.0081 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 EPE28818.1 - 0.0021 17.7 0.6 0.0084 15.7 0.4 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.12 EPE28818.1 - 0.046 12.7 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase HET PF06985.6 EPE28819.1 - 2.8e-30 105.2 0.1 5.1e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EPE28820.1 - 2.3e-22 79.2 70.9 7e-20 71.0 32.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.17 EPE28821.1 - 8.1e-37 124.6 0.0 1.3e-11 43.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE28821.1 - 3.6e-36 122.9 0.0 1e-07 31.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE28821.1 - 5.5e-18 64.5 0.0 0.0004 20.1 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EPE28821.1 - 4.7e-13 48.5 4.4 4.7e-13 48.5 3.0 3.6 4 0 0 4 4 4 1 Putative RRM domain RRM_3 PF08777.6 EPE28821.1 - 0.017 14.9 8.0 0.067 13.0 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif tRNA-synt_2 PF00152.15 EPE28822.1 - 6.9e-69 232.1 0.0 1.4e-68 231.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPE28822.1 - 1.4e-08 34.4 0.1 3.6e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Lipoprotein_16 PF03923.8 EPE28822.1 - 0.0031 16.8 0.1 0.079 12.3 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized lipoprotein tRNA_anti_2 PF13742.1 EPE28822.1 - 0.03 14.1 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DNA_ligase_A_M PF01068.16 EPE28823.1 - 2.6e-54 183.6 0.4 1.2e-52 178.2 0.3 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPE28823.1 - 1.1e-49 168.6 0.0 2.9e-49 167.2 0.0 1.8 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPE28823.1 - 4.8e-29 100.6 6.1 6e-28 97.1 0.0 3.7 4 0 0 4 4 4 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EPE28823.1 - 0.1 12.2 0.1 12 5.6 0.0 2.9 2 0 0 2 2 2 0 DNA ligase OB-like domain Med5 PF08689.5 EPE28823.1 - 1.5 6.4 9.0 2.7 5.5 6.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit Med5 Dec-1 PF04624.9 EPE28824.1 - 0.0046 16.5 1.5 0.014 15.0 1.0 1.8 1 0 0 1 1 1 1 Dec-1 repeat DUF3449 PF11931.3 EPE28824.1 - 5.6 6.4 9.0 8.4 5.8 6.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3449) Ras PF00071.17 EPE28825.1 - 7.4e-53 178.2 0.0 9.3e-53 177.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE28825.1 - 4.6e-16 59.3 0.0 9.1e-16 58.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPE28825.1 - 6e-07 28.8 0.0 8.4e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MFS_1 PF07690.11 EPE28826.1 - 3.1e-16 59.0 51.2 5.9e-10 38.3 20.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EPE28827.1 - 5.1e-06 25.5 0.0 8.6e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE28827.1 - 0.00018 21.3 7.9 0.00032 20.5 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE28828.1 - 7.5e-38 130.1 59.0 7.5e-38 130.1 40.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE28828.1 - 2.3e-13 49.5 11.5 2.3e-13 49.5 8.0 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter RAMP4 PF06624.7 EPE28828.1 - 0.21 11.1 4.1 0.24 10.9 0.8 2.5 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Methyltransf_2 PF00891.13 EPE28829.1 - 1.6e-29 102.7 0.0 2.1e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EPE28829.1 - 6.3e-05 23.5 0.0 0.00019 21.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE28829.1 - 0.0066 16.7 0.0 0.023 15.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_5 PF01795.14 EPE28829.1 - 0.033 13.4 0.0 5.9 6.0 0.0 2.3 2 0 0 2 2 2 0 MraW methylase family MTS PF05175.9 EPE28829.1 - 0.035 13.4 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EPE28829.1 - 0.075 12.0 0.1 0.2 10.6 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase DUF4242 PF14026.1 EPE28830.1 - 0.074 13.1 0.1 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) COesterase PF00135.23 EPE28831.1 - 1.7e-45 155.7 0.0 2e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family ketoacyl-synt PF00109.21 EPE28832.1 - 3.1e-72 243.1 1.5 1.9e-71 240.5 0.1 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EPE28832.1 - 1.2e-32 112.2 0.3 2.5e-32 111.2 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EPE28832.1 - 1.7e-25 90.0 1.3 4.6e-25 88.6 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EPE28832.1 - 4.3e-23 81.9 0.0 6.9e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_3 PF07859.8 EPE28832.1 - 7.5e-14 51.8 0.0 2e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_12 PF08242.7 EPE28832.1 - 1.3e-13 51.2 0.0 3.5e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 EPE28832.1 - 1.7e-13 50.5 0.0 7.2e-11 42.0 0.0 3.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE28832.1 - 3.1e-11 43.6 4.0 2.1e-10 40.9 0.1 3.4 3 1 0 3 3 3 1 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 EPE28832.1 - 3.4e-10 39.8 0.1 2.5e-09 37.0 0.0 2.6 4 0 0 4 4 1 1 Methyltransferase domain PP-binding PF00550.20 EPE28832.1 - 7.8e-10 38.8 3.0 2.5e-09 37.2 2.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Peptidase_S9 PF00326.16 EPE28832.1 - 4.8e-08 32.4 0.4 0.00043 19.5 0.0 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family Methyltransf_31 PF13847.1 EPE28832.1 - 7.2e-08 32.1 0.0 3e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE28832.1 - 7.3e-05 23.0 0.0 0.00035 20.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EPE28832.1 - 0.00011 21.2 0.0 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 EPE28832.1 - 0.00036 20.9 0.0 0.0018 18.6 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain DLH PF01738.13 EPE28832.1 - 0.00047 19.5 0.0 2.5 7.3 0.0 3.5 3 0 0 3 3 3 1 Dienelactone hydrolase family Methyltransf_18 PF12847.2 EPE28832.1 - 0.001 19.6 0.0 0.0034 17.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE28832.1 - 0.012 14.7 0.0 0.033 13.2 0.0 1.7 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Abhydrolase_2 PF02230.11 EPE28832.1 - 0.015 14.7 0.0 0.63 9.4 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.9 EPE28832.1 - 0.016 14.3 0.3 0.09 11.9 0.0 2.4 3 0 0 3 3 2 0 Secretory lipase DUF829 PF05705.9 EPE28832.1 - 0.052 13.2 0.0 0.39 10.3 0.0 2.4 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF829) Methyltransf_26 PF13659.1 EPE28832.1 - 0.077 13.0 0.0 0.29 11.1 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain ACP_syn_III PF08545.5 EPE28832.1 - 0.18 11.4 2.7 0.35 10.5 0.2 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MtrF PF09472.5 EPE28832.1 - 0.35 10.1 2.2 0.81 8.9 0.1 2.7 3 0 0 3 3 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF2920 PF11144.3 EPE28832.1 - 0.75 8.7 0.0 2.5 7.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) p450 PF00067.17 EPE28833.1 - 1.3e-40 139.3 0.0 2.4e-40 138.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SeqA PF03925.8 EPE28833.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 SeqA protein Transformer PF06495.6 EPE28834.1 - 0.016 15.1 1.7 0.031 14.1 1.2 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein FSH1 PF03959.8 EPE28835.1 - 4.7e-29 101.3 0.0 6.4e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EPE28835.1 - 5.4e-06 25.9 0.0 0.0038 16.7 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EPE28835.1 - 0.0064 16.4 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1524 PF07510.6 EPE28836.1 - 0.055 13.3 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) Isochorismatase PF00857.15 EPE28837.1 - 1.4e-42 145.5 0.0 1.9e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Abhydrolase_6 PF12697.2 EPE28838.1 - 3e-09 37.1 0.2 5.4e-09 36.2 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE28838.1 - 3.1e-06 27.0 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 EPE28840.1 - 5.2e-06 26.1 0.0 9.9e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE28840.1 - 5.5e-06 26.1 0.0 8.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE28840.1 - 0.002 18.4 0.0 0.0032 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF3328 PF11807.3 EPE28841.1 - 2e-25 89.7 0.0 2.5e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SCA7 PF08313.7 EPE28842.1 - 1.1e-30 105.0 1.8 1.1e-30 105.0 1.3 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain DUF2457 PF10446.4 EPE28842.1 - 0.46 9.1 23.1 0.37 9.4 14.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) DUF572 PF04502.8 EPE28842.1 - 2.7 7.1 22.2 5.1 6.2 15.4 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF572) CDC45 PF02724.9 EPE28842.1 - 8.7 4.2 16.5 13 3.6 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.17 EPE28843.1 - 2.9e-50 171.1 0.0 3.7e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Actin PF00022.14 EPE28844.1 - 2.4e-102 342.2 0.0 2.8e-102 342.0 0.0 1.0 1 0 0 1 1 1 1 Actin BBS2_N PF14781.1 EPE28844.1 - 0.19 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal GCIP PF13324.1 EPE28845.1 - 1.3e-05 24.5 2.9 3.4e-05 23.2 0.0 2.5 3 0 0 3 3 3 1 Grap2 and cyclin-D-interacting Thioredoxin_9 PF14595.1 EPE28845.1 - 0.014 14.9 0.0 0.038 13.5 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin Amino_oxidase PF01593.19 EPE28846.1 - 1.1e-33 116.9 0.1 2e-32 112.8 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPE28846.1 - 1.9e-11 43.8 0.0 5.2e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPE28846.1 - 0.0077 16.3 0.1 0.06 13.3 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE28846.1 - 0.0081 16.5 0.1 0.032 14.6 0.1 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPE28846.1 - 0.057 12.4 1.1 0.16 11.0 0.3 2.1 3 0 0 3 3 3 0 FAD binding domain Pec_lyase_C PF00544.14 EPE28848.1 - 1.5e-28 99.6 2.4 2e-28 99.2 1.6 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EPE28848.1 - 1.1e-07 31.7 14.9 3.5e-06 26.8 10.3 2.1 1 1 0 1 1 1 1 Right handed beta helix region Pectate_lyase_3 PF12708.2 EPE28848.1 - 0.001 19.2 8.0 0.11 12.6 5.5 2.3 1 1 0 1 1 1 1 Pectate lyase superfamily protein Sugar_tr PF00083.19 EPE28849.1 - 4.8e-89 299.0 22.8 5.9e-89 298.7 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE28849.1 - 3e-30 105.1 29.4 6.1e-23 81.0 3.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE28849.1 - 3.2e-06 25.8 22.0 0.0011 17.5 0.4 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Polysacc_deac_1 PF01522.16 EPE28850.1 - 6.7e-27 93.5 0.0 8.8e-27 93.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EPE28850.1 - 0.11 11.3 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 UFD1 PF03152.9 EPE28851.1 - 3.8e-23 81.5 0.0 2.4e-19 69.1 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 DUF2442 PF10387.4 EPE28851.1 - 0.018 15.0 0.0 1.6 8.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) Glyco_hydro_17 PF00332.13 EPE28853.1 - 3.1e-16 59.3 0.3 4.3e-16 58.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 CBM-like PF14683.1 EPE28854.1 - 4e-14 52.5 0.1 8.9e-14 51.4 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EPE28854.1 - 1.7e-11 44.0 0.2 4.6e-11 42.6 0.2 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EPE28854.1 - 0.005 16.8 0.1 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Bac_surface_Ag PF01103.18 EPE28855.1 - 1.5e-40 139.6 1.7 1.8e-40 139.3 1.2 1.1 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.21 EPE28856.1 - 7.9e-24 83.6 0.2 1.1e-23 83.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MARVEL PF01284.18 EPE28858.1 - 1.3e-23 83.4 17.4 1.5e-23 83.2 12.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain Transpos_assoc PF13963.1 EPE28859.1 - 0.041 13.8 0.3 14 5.7 0.0 2.8 1 1 1 2 2 2 0 Transposase-associated domain DSPc PF00782.15 EPE28860.1 - 2.8e-24 85.1 0.0 3.5e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPE28860.1 - 1.4e-05 24.5 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EPE28860.1 - 0.0036 16.2 0.0 0.0038 16.1 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 EPE28860.1 - 0.0058 16.6 0.0 0.0078 16.2 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Sugar_tr PF00083.19 EPE28861.1 - 6.6e-30 104.0 26.4 2.4e-29 102.2 18.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE28861.1 - 7.2e-27 94.0 31.1 6.9e-23 80.9 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyto_heme_lyase PF01265.12 EPE28865.1 - 6.7e-76 255.2 0.0 7.6e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.11 EPE28866.1 - 6.7e-24 84.1 0.0 8.2e-14 51.6 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 EPE28866.1 - 0.0078 15.9 0.4 0.016 14.9 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrzO PF14142.1 EPE28866.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 YrzO-like protein RIO1 PF01163.17 EPE28866.1 - 0.17 11.1 0.0 0.39 10.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Med7 PF05983.6 EPE28867.1 - 0.046 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 MED7 protein RRM_5 PF13893.1 EPE28869.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_Tnp_1_4 PF13701.1 EPE28869.1 - 0.33 9.0 3.1 0.53 8.4 2.1 1.2 1 0 0 1 1 1 0 Transposase DDE domain group 1 AA_permease_2 PF13520.1 EPE28870.1 - 1.3e-69 234.7 36.6 1.8e-69 234.3 25.3 1.1 1 0 0 1 1 1 1 Amino acid permease TauD PF02668.11 EPE28871.1 - 6e-30 104.7 0.1 7.6e-30 104.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EPE28871.1 - 0.073 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 CsiD Vac7 PF12751.2 EPE28874.1 - 0.0031 16.4 1.3 0.0048 15.8 0.9 1.3 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 CRC_subunit PF08624.5 EPE28875.1 - 3.2e-35 121.0 0.2 5.7e-35 120.2 0.1 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Spermine_synth PF01564.12 EPE28876.1 - 3.1e-07 29.5 0.0 6.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase MR_MLE_C PF13378.1 EPE28877.1 - 2.7e-19 69.1 0.0 9.1e-19 67.4 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EPE28877.1 - 2.3e-12 47.2 0.0 6.7e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EPE28877.1 - 0.00035 20.5 0.3 0.0014 18.6 0.0 2.0 3 0 0 3 3 3 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EPE28877.1 - 0.017 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus DAO PF01266.19 EPE28879.1 - 1.6e-26 93.0 0.9 8e-26 90.7 0.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE28879.1 - 0.00018 21.4 0.4 0.00018 21.4 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE28879.1 - 0.00099 18.0 0.0 0.0023 16.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EPE28879.1 - 0.0071 15.4 0.2 0.014 14.4 0.0 1.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EPE28879.1 - 0.017 14.2 0.0 0.22 10.5 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain Pyr_redox PF00070.22 EPE28879.1 - 0.017 15.5 3.2 0.049 14.0 0.2 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE28879.1 - 0.023 14.5 0.1 0.046 13.5 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EPE28879.1 - 0.083 12.6 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 EPE28879.1 - 0.12 12.1 0.0 0.71 9.6 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding NDT80_PhoG PF05224.7 EPE28880.1 - 2.1e-32 112.6 0.0 9.3e-32 110.5 0.0 2.0 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Hexokinase_2 PF03727.11 EPE28881.1 - 3.1e-34 118.2 0.0 4.6e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EPE28881.1 - 1.5e-33 115.8 0.0 2.3e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Glucosamine_iso PF01182.15 EPE28882.1 - 3.1e-25 89.0 0.0 4.7e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Peroxidase_2 PF01328.12 EPE28884.1 - 2.4e-11 42.8 0.6 2.4e-11 42.8 0.4 2.3 2 1 1 3 3 3 1 Peroxidase, family 2 Glyco_hydro_3 PF00933.16 EPE28885.1 - 1.6e-55 188.1 0.0 2.4e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_7 PF13508.1 EPE28885.1 - 7.7e-06 25.9 0.0 2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 EPE28885.1 - 0.00044 19.8 0.0 0.00088 18.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 EPE28885.1 - 0.0055 16.7 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE28885.1 - 0.033 14.3 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidohydro_4 PF13147.1 EPE28886.1 - 3.6e-11 43.6 0.1 2.5e-09 37.6 0.1 2.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EPE28886.1 - 1.3e-06 28.3 0.0 9.6e-06 25.4 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EPE28886.1 - 0.00011 21.6 0.1 0.00026 20.3 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EPE28886.1 - 0.00077 19.2 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase F-box-like PF12937.2 EPE28887.1 - 1.1e-07 31.4 0.9 1.7e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EPE28887.1 - 0.0073 15.9 1.7 5.6 6.6 0.0 4.0 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EPE28887.1 - 0.012 15.6 1.2 3 8.2 0.4 4.1 5 0 0 5 5 5 0 Leucine Rich repeat F-box PF00646.28 EPE28887.1 - 0.024 14.3 0.0 0.069 12.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain Fungal_trans PF04082.13 EPE28888.1 - 3.9e-10 39.0 0.8 5.7e-10 38.5 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE28888.1 - 2.3e-08 33.7 10.7 4.7e-08 32.8 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aspzincin_M35 PF14521.1 EPE28892.1 - 0.033 14.7 0.1 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase APH PF01636.18 EPE28893.1 - 7.6e-12 45.4 0.0 2.8e-11 43.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EPE28893.1 - 0.00023 20.4 0.1 0.00034 19.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EPE28893.1 - 0.0067 15.1 0.0 0.013 14.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) RIO1 PF01163.17 EPE28893.1 - 0.0094 15.3 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Glyco_hydro_16 PF00722.16 EPE28895.1 - 1.5e-36 125.4 1.4 1.5e-36 125.4 1.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 WD40 PF00400.27 EPE28897.1 - 4.4e-48 159.5 24.3 6.9e-12 44.7 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EPE28897.1 - 4.2e-09 36.3 12.7 0.0093 15.6 0.1 4.6 2 2 3 5 5 5 3 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 EPE28897.1 - 0.052 11.3 4.2 0.2 9.3 0.1 2.1 2 0 0 2 2 2 0 IKI3 family SAD_SRA PF02182.12 EPE28899.1 - 3.4e-32 110.8 0.1 4.9e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 SAD/SRA domain Dscam_C PF12355.3 EPE28899.1 - 1.1 9.4 5.9 2.8 8.2 0.3 2.4 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal ABC2_membrane PF01061.19 EPE28900.1 - 1.9e-83 278.7 57.0 1.4e-42 145.2 13.5 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPE28900.1 - 6.2e-36 123.7 0.0 4.4e-18 65.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EPE28900.1 - 1.7e-27 95.0 5.1 6.6e-25 86.7 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EPE28900.1 - 9.3e-09 35.2 0.2 3.9e-08 33.2 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 EPE28900.1 - 3.8e-06 26.8 0.1 0.0018 18.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EPE28900.1 - 4.7e-06 26.7 0.1 0.071 13.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EPE28900.1 - 7.4e-06 25.4 0.2 0.002 17.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EPE28900.1 - 2.7e-05 24.9 0.0 0.018 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EPE28900.1 - 3.8e-05 23.7 1.2 0.036 14.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EPE28900.1 - 0.0001 21.7 0.1 0.0049 16.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EPE28900.1 - 0.00015 20.9 47.5 0.006 15.6 18.1 3.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 EPE28900.1 - 0.00024 21.1 0.2 0.023 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EPE28900.1 - 0.00028 20.3 0.9 0.0086 15.5 0.3 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EPE28900.1 - 0.0004 20.5 0.2 0.17 12.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPE28900.1 - 0.001 18.7 6.1 0.84 9.4 0.0 3.6 3 0 0 3 3 3 1 Part of AAA domain DUF258 PF03193.11 EPE28900.1 - 0.0011 18.1 0.0 0.0048 16.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EPE28900.1 - 0.0018 17.5 0.0 0.31 10.2 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EPE28900.1 - 0.0034 17.6 0.0 0.27 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EPE28900.1 - 0.0047 16.5 0.6 1.8 8.1 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EPE28900.1 - 0.0072 15.8 0.1 0.83 9.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 EPE28900.1 - 0.014 15.0 0.3 5.1 6.7 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 EPE28900.1 - 0.014 14.8 1.5 0.4 10.0 0.0 2.6 3 0 0 3 3 2 0 AAA-like domain PduV-EutP PF10662.4 EPE28900.1 - 0.034 13.6 0.2 2.4 7.6 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EPE28900.1 - 0.047 13.3 0.0 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EPE28900.1 - 0.073 13.2 0.1 13 5.9 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 EPE28900.1 - 0.099 11.0 0.6 18 3.5 0.0 3.3 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.1 EPE28900.1 - 0.13 11.2 0.0 3.9 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 EPE28900.1 - 0.16 12.4 0.0 9.4 6.7 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein Spherulin4 PF12138.3 EPE28901.1 - 1.4e-40 139.3 4.4 1.6e-40 139.1 3.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 DUF1510 PF07423.6 EPE28901.1 - 0.34 10.2 10.7 0.53 9.6 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 EPE28901.1 - 0.64 8.7 10.4 0.9 8.2 7.2 1.2 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 EPE28901.1 - 6.1 4.7 15.8 7.8 4.3 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EPE28901.1 - 8.4 4.1 25.9 10 3.8 17.9 1.1 1 0 0 1 1 1 0 Nop14-like family Ricin_B_lectin PF00652.17 EPE28902.1 - 2.3e-13 50.2 3.2 4.4e-13 49.3 2.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase PF02065.13 EPE28902.1 - 4.8e-11 41.9 0.0 1.8e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Melibiase CDtoxinA PF03498.9 EPE28902.1 - 0.0029 16.9 0.2 0.0065 15.8 0.1 1.5 1 0 0 1 1 1 1 Cytolethal distending toxin A/C family PhyH PF05721.8 EPE28903.1 - 9.5e-10 38.8 0.0 2.7e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ESX-1_EspG PF14011.1 EPE28903.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 EspG family NAD_binding_10 PF13460.1 EPE28904.1 - 5.7e-13 49.2 0.0 1e-12 48.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE28904.1 - 3.8e-12 46.1 0.0 1.6e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE28904.1 - 2.4e-07 29.7 0.0 1.6e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EPE28904.1 - 6.3e-07 28.8 0.2 7.8e-05 22.0 0.2 2.1 2 0 0 2 2 2 1 NmrA-like family TrkA_N PF02254.13 EPE28904.1 - 1.7e-05 24.7 0.5 2.7e-05 24.1 0.4 1.3 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 EPE28904.1 - 2.2e-05 24.4 0.5 7.4e-05 22.7 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EPE28904.1 - 0.00012 21.0 0.0 0.086 11.7 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.19 EPE28904.1 - 0.00023 21.4 0.1 0.00038 20.7 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EPE28904.1 - 0.0003 19.8 0.2 0.0005 19.0 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EPE28904.1 - 0.00036 20.8 0.3 0.00075 19.8 0.2 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 EPE28904.1 - 0.002 17.0 0.0 0.69 8.7 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain KR PF08659.5 EPE28904.1 - 0.0083 15.8 0.2 0.022 14.4 0.1 1.7 1 1 0 1 1 1 1 KR domain DapB_N PF01113.15 EPE28904.1 - 0.011 15.7 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 EPE28904.1 - 0.026 14.6 0.4 0.042 13.9 0.3 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.11 EPE28904.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF1237 PF06824.6 EPE28907.1 - 8e-174 578.1 0.0 9.7e-174 577.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Herpes_LMP2 PF07415.6 EPE28908.1 - 0.58 8.6 1.2 1.2 7.6 0.8 1.5 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Nuc_deoxyrib_tr PF05014.10 EPE28909.1 - 0.00014 21.7 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase DUF2872 PF11071.3 EPE28909.1 - 0.1 12.4 0.0 0.66 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2872) UvrD_C PF13361.1 EPE28912.1 - 6.4e-77 259.3 0.1 1e-76 258.7 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EPE28912.1 - 3.5e-60 203.9 3.3 1.1e-58 198.9 0.2 2.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EPE28912.1 - 5.2e-15 55.4 0.0 2.7e-14 53.1 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EPE28912.1 - 6.4e-11 41.8 0.2 3.6e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EPE28912.1 - 3.2e-07 30.1 0.1 2.8e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EPE28912.1 - 1.4e-05 24.7 0.3 0.054 12.9 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 EPE28912.1 - 0.0025 17.2 0.4 0.0077 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE28912.1 - 0.049 13.7 0.3 8.1 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain DIOX_N PF14226.1 EPE28913.1 - 3.8e-31 108.0 0.0 5.3e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPE28913.1 - 1.9e-25 88.9 0.0 3.6e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CBM_2 PF00553.14 EPE28914.1 - 0.039 13.9 0.4 0.14 12.2 0.1 1.8 2 0 0 2 2 2 0 Cellulose binding domain ABC_tran PF00005.22 EPE28916.1 - 1.4e-47 161.4 0.9 3.6e-23 82.3 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EPE28916.1 - 6.6e-20 70.7 7.8 6.6e-20 70.7 5.4 2.9 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 EPE28916.1 - 8.9e-16 58.6 1.1 0.0044 17.0 0.5 4.5 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EPE28916.1 - 1.9e-11 43.6 0.4 0.0073 15.5 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EPE28916.1 - 9.4e-09 36.1 0.1 0.01 16.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EPE28916.1 - 2e-06 27.9 1.2 0.0005 20.1 0.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EPE28916.1 - 2.6e-06 27.9 0.4 0.028 14.9 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_29 PF13555.1 EPE28916.1 - 2.8e-06 26.7 0.3 0.063 12.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EPE28916.1 - 7.1e-06 26.1 0.0 0.31 11.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPE28916.1 - 9.5e-06 24.8 0.0 0.051 12.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 EPE28916.1 - 1.5e-05 24.7 0.2 0.26 10.9 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EPE28916.1 - 2.6e-05 24.1 0.0 0.072 13.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EPE28916.1 - 2.8e-05 24.4 1.9 0.29 11.4 0.0 3.4 5 0 0 5 5 2 2 AAA domain AAA PF00004.24 EPE28916.1 - 7e-05 23.0 0.1 0.44 10.7 0.1 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EPE28916.1 - 9.6e-05 22.0 0.1 0.24 11.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 EPE28916.1 - 9.8e-05 22.2 0.1 0.37 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EPE28916.1 - 0.00016 21.5 0.2 0.91 9.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 EPE28916.1 - 0.00026 21.3 0.4 0.0062 16.8 0.0 4.5 5 0 0 5 5 4 2 AAA domain AAA_15 PF13175.1 EPE28916.1 - 0.0003 19.9 9.8 0.35 9.8 0.0 4.4 4 2 1 5 5 5 2 AAA ATPase domain AAA_10 PF12846.2 EPE28916.1 - 0.0011 18.5 0.5 1.8 7.9 0.0 3.1 2 1 1 3 3 3 2 AAA-like domain RNA_helicase PF00910.17 EPE28916.1 - 0.0017 18.5 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 EPE28916.1 - 0.0022 17.4 0.0 2.3 7.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EPE28916.1 - 0.0023 16.7 0.2 1.4 7.6 0.0 2.5 2 0 0 2 2 2 2 ArgK protein Dynamin_N PF00350.18 EPE28916.1 - 0.0026 17.6 4.4 0.81 9.4 0.0 3.8 3 1 0 3 3 3 1 Dynamin family AAA_28 PF13521.1 EPE28916.1 - 0.0031 17.5 4.8 0.18 11.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 EPE28916.1 - 0.0042 16.8 0.1 0.77 9.4 0.0 2.7 2 0 0 2 2 2 1 NTPase ATP-synt_ab PF00006.20 EPE28916.1 - 0.0087 15.5 0.4 1.4 8.3 0.0 2.6 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 EPE28916.1 - 0.0088 15.1 1.5 0.51 9.4 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin cobW PF02492.14 EPE28916.1 - 0.011 15.1 1.0 2.1 7.7 0.5 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EPE28916.1 - 0.014 15.2 0.2 10 6.1 0.1 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 EPE28916.1 - 0.017 14.0 0.0 5 5.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 EPE28916.1 - 0.017 14.8 0.3 4.8 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EPE28916.1 - 0.023 14.2 0.2 6.6 6.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EPE28916.1 - 0.029 13.8 0.2 4.6 6.6 0.1 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 EPE28916.1 - 0.059 12.8 0.2 9.8 5.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EPE28916.1 - 3.4 7.3 9.8 26 4.3 0.0 4.0 4 0 0 4 4 4 0 Archaeal ATPase Tubulin PF00091.20 EPE28917.1 - 8.2e-70 234.9 0.0 1.3e-69 234.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPE28917.1 - 1.1e-48 164.3 0.1 1.9e-48 163.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EPE28917.1 - 1.5e-05 25.0 0.0 4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EPE28917.1 - 0.0049 16.3 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Arginosuc_synth PF00764.14 EPE28918.1 - 1.1e-154 515.1 0.0 1.3e-154 514.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EPE28918.1 - 0.0031 17.0 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EPE28918.1 - 0.0047 16.2 0.0 0.008 15.4 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EPE28918.1 - 0.036 12.6 0.0 0.055 12.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase CIA30 PF08547.7 EPE28919.1 - 4.3e-38 130.6 0.1 4.9e-38 130.4 0.1 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.16 EPE28920.1 - 0.00018 21.4 7.4 0.00031 20.6 5.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPE28920.1 - 0.0023 17.7 6.9 0.0037 17.0 4.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPE28920.1 - 0.029 14.6 3.8 0.055 13.7 2.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Na_H_Exchanger PF00999.16 EPE28922.1 - 3e-69 233.3 45.1 4e-69 232.9 31.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_C PF02080.16 EPE28923.1 - 0.082 12.5 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-C domain bZIP_1 PF00170.16 EPE28925.1 - 3.3e-12 46.1 3.7 4.9e-12 45.6 2.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPE28925.1 - 2.5e-06 27.2 7.1 4.1e-06 26.5 4.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper THOC7 PF05615.8 EPE28925.1 - 0.042 14.1 0.4 0.059 13.6 0.3 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 bZIP_Maf PF03131.12 EPE28925.1 - 0.13 12.5 2.9 0.23 11.7 2.0 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor GSDH PF07995.6 EPE28926.1 - 1.7e-05 24.0 0.1 6.6e-05 22.1 0.1 2.1 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 EPE28926.1 - 0.00055 19.3 0.3 0.097 12.0 0.0 2.6 3 0 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 EPE28926.1 - 0.0018 17.4 0.1 0.11 11.5 0.0 2.8 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller NHL PF01436.16 EPE28926.1 - 0.027 14.4 0.0 32 4.7 0.0 4.0 4 0 0 4 4 4 0 NHL repeat B9-C2 PF07162.6 EPE28926.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein Adeno_PVIII PF01310.13 EPE28926.1 - 0.084 12.6 0.0 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 Adenovirus hexon associated protein, protein VIII Reg_prop PF07494.6 EPE28926.1 - 0.086 12.9 0.1 4.3 7.6 0.0 3.2 2 1 1 3 3 3 0 Two component regulator propeller stn_TNFRSF12A PF12191.3 EPE28929.1 - 0.00029 20.8 2.6 0.71 9.9 0.1 2.9 1 1 1 2 2 2 2 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain EphA2_TM PF14575.1 EPE28929.1 - 0.068 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 EPE28929.1 - 0.18 11.1 0.4 0.35 10.2 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Plug PF07715.10 EPE28930.1 - 0.035 14.4 0.1 0.055 13.7 0.1 1.2 1 0 0 1 1 1 0 TonB-dependent Receptor Plug Domain Antimicrobial_2 PF08023.7 EPE28932.1 - 2 8.7 5.7 1.3e+02 3.0 0.1 4.1 4 0 0 4 4 4 0 Frog antimicrobial peptide TcdA_TcdB_pore PF12920.2 EPE28933.1 - 0.011 13.7 0.2 0.017 13.0 0.1 1.3 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain CagE_TrbE_VirB PF03135.9 EPE28935.1 - 0.028 14.2 0.6 0.054 13.2 0.4 1.4 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Asp_Glu_race PF01177.17 EPE28937.1 - 3.7e-18 66.2 0.0 4.3e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase GMC_oxred_N PF00732.14 EPE28940.1 - 1.6e-54 185.1 0.0 2e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE28940.1 - 2.9e-34 118.4 0.0 5.8e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPE28940.1 - 3.1e-06 26.3 4.5 4.4e-05 22.5 3.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE28940.1 - 4.4e-05 22.5 0.1 7.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPE28940.1 - 0.0011 18.9 0.1 0.0036 17.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EPE28940.1 - 0.0051 15.3 0.4 0.94 7.8 0.0 2.6 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.1 EPE28940.1 - 0.027 14.2 1.3 0.063 13.0 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding TfuA PF07812.7 EPE28940.1 - 0.042 13.2 0.1 0.13 11.7 0.1 1.8 1 0 0 1 1 1 0 TfuA-like protein Pyr_redox_2 PF07992.9 EPE28940.1 - 0.052 13.4 0.0 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease PF00324.16 EPE28941.1 - 1.5e-107 359.8 32.3 1.9e-107 359.5 22.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE28941.1 - 1.6e-19 69.7 35.1 2.2e-19 69.3 24.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EPE28941.1 - 0.017 14.8 2.5 0.017 14.8 1.7 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF1772) DUF3487 PF11990.3 EPE28941.1 - 0.02 14.2 0.0 0.02 14.2 0.0 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF3487) Orai-1 PF07856.7 EPE28941.1 - 4.1 6.9 13.2 1 8.9 2.9 2.6 2 0 0 2 2 2 0 Mediator of CRAC channel activity HET PF06985.6 EPE28942.1 - 0.0027 17.8 0.0 0.0033 17.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1989 PF09347.5 EPE28944.1 - 7.5e-52 175.1 0.0 9.4e-52 174.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) AA_permease PF00324.16 EPE28945.1 - 4.7e-108 361.5 50.5 5.9e-108 361.2 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE28945.1 - 7.4e-23 80.7 56.3 9.4e-23 80.4 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2252 PF10009.4 EPE28946.1 - 0.85 8.4 6.1 1.4 7.7 4.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Glyco_hydro_61 PF03443.9 EPE28947.1 - 3.5e-31 108.7 0.1 4.3e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 UPF0029 PF01205.14 EPE28948.1 - 3.1e-27 94.4 0.0 6e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF3210 PF11489.3 EPE28949.1 - 6.8e-207 689.4 69.6 6.8e-207 689.4 48.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 EPE28950.1 - 1.5e-38 131.2 11.6 1.8e-38 130.9 8.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF2207 PF09972.4 EPE28950.1 - 0.14 10.6 6.3 0.17 10.4 4.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PRA1 PF03208.14 EPE28950.1 - 0.47 9.7 9.6 0.65 9.3 6.7 1.2 1 0 0 1 1 1 0 PRA1 family protein Not1 PF04054.10 EPE28951.1 - 1.2e-123 412.7 0.7 2.2e-123 411.8 0.5 1.4 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EPE28951.1 - 3.4e-45 153.3 5.7 3.4e-45 153.3 3.9 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) ADH_zinc_N PF00107.21 EPE28953.1 - 7.7e-15 54.5 0.2 1.2e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE28953.1 - 8.1e-09 35.2 0.0 1.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FCH PF00611.18 EPE28954.1 - 1e-21 76.8 0.1 3.4e-21 75.2 0.1 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EPE28954.1 - 3.6e-13 48.6 0.0 7.1e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPE28954.1 - 2.4e-11 43.0 0.0 4.2e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPE28954.1 - 1.7e-10 40.1 0.0 3.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Seipin PF06775.9 EPE28955.1 - 4.7e-56 189.4 0.2 6e-56 189.1 0.2 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Pkinase PF00069.20 EPE28956.1 - 2.7e-76 256.1 0.0 3.8e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE28956.1 - 4.6e-39 134.0 0.1 4.9e-38 130.6 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EPE28956.1 - 1.1e-17 63.1 0.1 1.9e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EPE28956.1 - 4.2e-06 25.9 0.2 8.2e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPE28956.1 - 8.4e-05 21.6 0.0 0.00024 20.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPE28956.1 - 0.0021 17.8 0.3 0.038 13.7 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 EPE28956.1 - 0.0026 17.0 0.1 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EPE28956.1 - 0.0033 16.8 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 EPE28956.1 - 0.038 13.3 0.2 0.11 11.7 0.2 1.8 1 1 0 1 1 1 0 RIO1 family DUF1604 PF07713.8 EPE28957.1 - 9.2e-38 127.9 2.1 9.2e-38 127.9 1.4 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EPE28957.1 - 1.2e-08 34.5 1.2 7.3e-08 32.0 0.4 2.6 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EPE28957.1 - 0.0013 18.5 0.5 0.0013 18.5 0.4 3.4 2 2 1 3 3 3 1 DExH-box splicing factor binding site ADH_N PF08240.7 EPE28958.1 - 3.9e-11 42.6 0.0 2.5e-10 40.0 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE28958.1 - 3.7e-09 36.2 0.1 5.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TBP PF00352.16 EPE28959.1 - 4e-70 231.2 0.2 3.9e-35 119.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EPE28959.1 - 0.00022 21.2 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DAO PF01266.19 EPE28960.1 - 6.3e-52 176.6 0.0 7.6e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EPE28960.1 - 2.2e-05 23.5 0.0 0.00013 20.9 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EPE28960.1 - 2.7e-05 23.9 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EPE28960.1 - 4e-05 23.5 0.0 9.6e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE28960.1 - 7.1e-05 22.7 0.0 0.32 10.8 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPE28960.1 - 0.0028 16.6 0.0 0.0051 15.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EPE28960.1 - 0.0085 14.9 0.0 0.85 8.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EPE28960.1 - 0.026 14.5 0.0 0.33 10.9 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EPE28960.1 - 0.03 12.9 0.0 3.5 6.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.22 EPE28960.1 - 0.053 13.9 0.0 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EPE28960.1 - 0.089 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Surp PF01805.15 EPE28961.1 - 7.3e-17 60.7 0.0 1.3e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Surp module Pkinase PF00069.20 EPE28962.1 - 4.9e-20 71.7 0.2 3.9e-14 52.4 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE28962.1 - 0.00035 19.7 0.1 0.0011 18.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Sec7_N PF12783.2 EPE28963.1 - 3.6e-37 127.3 0.2 3.6e-37 127.3 0.1 3.8 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EPE28963.1 - 0.00097 18.6 0.0 0.016 14.6 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) UQ_con PF00179.21 EPE28964.1 - 4.3e-10 39.1 0.1 4.5e-08 32.6 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Complex1_LYR PF05347.10 EPE28965.1 - 1.8e-05 24.4 0.1 8.6e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPE28965.1 - 0.00054 20.1 0.3 0.0029 17.7 0.0 2.3 2 0 0 2 2 2 1 Complex1_LYR-like Telomere_Sde2 PF13019.1 EPE28965.1 - 7.9 6.1 6.8 18 5.0 4.7 1.6 1 0 0 1 1 1 0 Telomere stability and silencing HSP70 PF00012.15 EPE28966.1 - 8.6e-09 33.8 4.0 1e-08 33.6 0.3 2.0 2 0 0 2 2 2 2 Hsp70 protein bZIP_1 PF00170.16 EPE28967.1 - 6.7e-06 25.9 1.2 1.8e-05 24.5 0.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor Rcd1 PF04078.8 EPE28968.1 - 7.5e-131 434.7 3.1 9.1e-131 434.4 2.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like NSP2-B_epitope PF14757.1 EPE28968.1 - 0.059 12.8 1.0 0.12 11.8 0.7 1.4 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein V-ATPase_H_N PF03224.9 EPE28968.1 - 0.54 9.3 3.8 7.6 5.5 0.1 2.7 1 1 0 1 1 1 0 V-ATPase subunit H OSCP PF00213.13 EPE28968.1 - 0.78 9.5 4.6 1.5 8.6 0.0 2.6 2 1 0 2 2 2 0 ATP synthase delta (OSCP) subunit BAF1_ABF1 PF04684.8 EPE28968.1 - 5.3 5.7 10.2 7.2 5.3 7.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor BTB PF00651.26 EPE28969.1 - 6.1e-07 29.4 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EPE28970.1 - 1.8e-10 40.7 0.0 2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain SnoaL PF07366.7 EPE28970.1 - 0.043 13.4 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase PI3K_rbd PF00794.13 EPE28970.1 - 0.077 12.9 0.0 0.11 12.4 0.0 1.3 1 1 0 1 1 1 0 PI3-kinase family, ras-binding domain Ribosomal_L29 PF00831.18 EPE28970.1 - 0.091 12.4 0.0 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Ribosomal L29 protein F-box-like PF12937.2 EPE28971.1 - 0.0008 19.0 0.2 0.0022 17.6 0.1 1.8 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EPE28971.1 - 0.036 13.6 4.3 21 4.8 0.2 5.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Glyco_transf_15 PF01793.11 EPE28972.1 - 2.5e-97 325.8 6.8 2.4e-58 197.6 4.5 2.1 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Hira PF07569.6 EPE28973.1 - 1.8e-86 288.9 0.1 3.6e-86 287.9 0.0 1.6 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 EPE28973.1 - 1.6e-37 126.0 22.2 6e-07 29.0 0.0 8.9 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 EPE28973.1 - 1.6e-11 43.4 0.9 2.9e-11 42.5 0.6 1.5 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EPE28973.1 - 0.0049 16.5 1.2 15 5.3 0.0 4.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Band_7 PF01145.20 EPE28974.1 - 8.6e-30 103.9 0.6 1.4e-29 103.2 0.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EPE28974.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DRTGG PF07085.7 EPE28974.1 - 0.11 12.0 1.0 0.87 9.2 0.0 2.5 2 1 0 2 2 2 0 DRTGG domain zf-U1 PF06220.7 EPE28975.1 - 5.1e-05 22.7 0.5 8.5e-05 22.0 0.4 1.4 1 0 0 1 1 1 1 U1 zinc finger Thioredoxin PF00085.15 EPE28975.1 - 0.17 11.5 0.9 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin CCDC84 PF14968.1 EPE28975.1 - 0.23 10.9 3.9 0.6 9.5 2.7 1.8 1 1 0 1 1 1 0 Coiled coil protein 84 ADH_N PF08240.7 EPE28976.1 - 1.1e-06 28.4 0.0 2.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE28976.1 - 0.00021 20.8 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2314 PF10077.4 EPE28976.1 - 0.00041 20.3 0.0 0.00079 19.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2314) XH PF03469.9 EPE28979.1 - 0.0011 18.6 8.2 1.2 8.8 0.0 3.6 3 1 0 3 3 3 3 XH domain Peptidase_M41 PF01434.13 EPE28979.1 - 0.0039 16.7 5.7 0.0048 16.4 1.1 2.7 2 1 1 3 3 3 1 Peptidase family M41 KorB PF08535.5 EPE28979.1 - 0.019 15.1 9.6 1.2 9.3 0.0 4.8 5 0 0 5 5 5 0 KorB domain Globin PF00042.17 EPE28979.1 - 0.21 11.9 5.6 5.9 7.2 0.0 3.7 3 1 1 5 5 5 0 Globin BRX_N PF13713.1 EPE28979.1 - 0.31 10.5 5.2 0.3 10.5 0.2 3.5 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain Prominin PF05478.6 EPE28979.1 - 1.4 6.3 3.3 19 2.6 0.0 2.4 1 1 0 2 2 2 0 Prominin GlutR_dimer PF00745.15 EPE28979.1 - 1.7 8.5 6.0 2 8.4 0.0 3.6 4 0 0 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF883 PF05957.8 EPE28979.1 - 3 8.2 0.0 3 8.2 0.0 5.6 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF883) Mgm101p PF06420.7 EPE28980.1 - 7.1e-91 302.1 0.0 8.9e-91 301.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 FAM220 PF15487.1 EPE28980.1 - 0.42 9.9 2.5 0.67 9.2 1.7 1.2 1 0 0 1 1 1 0 FAM220 family DUF2360 PF10152.4 EPE28980.1 - 0.81 9.9 3.6 1.3 9.3 2.5 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) BPL_N PF09825.4 EPE28981.1 - 1.5e-145 484.6 0.0 1.9e-145 484.3 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EPE28981.1 - 4.4e-21 75.1 0.0 9.1e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HET PF06985.6 EPE28982.1 - 4.7e-22 78.6 0.6 1.2e-21 77.3 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TB2_DP1_HVA22 PF03134.14 EPE28983.1 - 5.8e-28 96.4 6.2 8.6e-28 95.9 4.3 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family NRDE PF05742.7 EPE28984.1 - 3.5e-46 157.7 0.0 4.9e-45 153.9 0.0 2.0 1 1 0 1 1 1 1 NRDE protein DUF4501 PF14946.1 EPE28985.1 - 0.0013 18.3 1.3 0.0016 17.9 0.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4501) DUF1772 PF08592.6 EPE28987.1 - 6.1e-16 58.4 2.0 7.7e-16 58.0 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Aldedh PF00171.17 EPE28988.1 - 2.8e-153 510.5 0.1 3.2e-153 510.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3445 PF11927.3 EPE28989.1 - 1.5e-65 221.0 0.0 1.9e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) NTF2 PF02136.15 EPE28990.1 - 1.8e-18 67.0 0.9 2e-18 66.8 0.6 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 EPE28990.1 - 0.00043 20.4 0.0 0.00057 20.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4518 PF15008.1 EPE28990.1 - 0.0062 15.6 0.3 0.031 13.2 0.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) Beta-lactamase PF00144.19 EPE28992.1 - 2.1e-43 148.6 0.3 3e-43 148.0 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EPE28992.1 - 4.7e-10 39.2 0.0 8.3e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) zf-primase PF09329.6 EPE28993.1 - 1.3e-18 66.2 1.6 2.5e-18 65.3 1.1 1.5 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.5 EPE28994.1 - 8.6e-91 304.2 2.8 1.1e-90 303.9 1.9 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DASH_Duo1 PF08651.5 EPE28995.1 - 2.2e-32 110.4 2.6 3.1e-32 109.9 1.8 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 Macoilin PF09726.4 EPE28995.1 - 0.66 8.1 8.1 0.86 7.8 5.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1764 PF08576.5 EPE28995.1 - 3 8.6 5.8 26 5.6 0.6 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) TTL PF03133.10 EPE28997.1 - 1.2e-53 181.9 0.0 1.9e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EPE28997.1 - 1e-43 148.9 0.0 1.6e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 EPE28997.1 - 9.4e-05 21.3 0.0 0.015 14.0 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EPE28997.1 - 0.00013 21.7 0.2 0.015 15.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain CsbD PF05532.7 EPE28999.1 - 0.0052 16.4 6.4 0.017 14.8 4.4 2.0 1 1 0 1 1 1 1 CsbD-like Mito_carr PF00153.22 EPE29000.1 - 1.4e-68 226.6 1.8 1.8e-24 85.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Dna2 PF08696.6 EPE29001.1 - 1.2e-68 230.5 0.0 2.4e-68 229.5 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EPE29001.1 - 1.1e-52 178.3 0.0 2.4e-52 177.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPE29001.1 - 8.2e-38 130.3 7.5 1.2e-36 126.4 0.5 2.7 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.1 EPE29001.1 - 5.2e-12 45.7 0.0 2e-11 43.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE29001.1 - 1.9e-11 43.5 0.2 4.6e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 EPE29001.1 - 2.5e-08 33.9 0.2 1.2e-06 28.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 EPE29001.1 - 8.3e-08 31.9 0.1 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 EPE29001.1 - 3.1e-07 30.1 2.2 0.28 10.6 0.1 4.0 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EPE29001.1 - 1.7e-05 24.5 0.0 4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Helicase DUF911 PF06023.7 EPE29001.1 - 0.00026 20.3 0.1 0.00098 18.4 0.1 1.9 1 1 0 1 1 1 1 Archaeal protein of unknown function (DUF911) UvrD-helicase PF00580.16 EPE29001.1 - 0.00037 19.9 0.8 0.00099 18.4 0.5 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 EPE29001.1 - 0.00084 18.8 0.1 0.0016 17.9 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 EPE29001.1 - 0.0012 18.3 0.1 0.0028 17.1 0.1 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EPE29001.1 - 0.0018 17.9 0.2 0.0044 16.7 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 EPE29001.1 - 0.0019 17.1 0.1 0.0055 15.7 0.1 1.7 1 1 0 1 1 1 1 PIF1-like helicase AAA_25 PF13481.1 EPE29001.1 - 0.0047 16.3 0.1 0.09 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EPE29001.1 - 0.0056 15.6 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EPE29001.1 - 0.0057 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.12 EPE29001.1 - 0.032 14.0 0.2 0.11 12.2 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF87 RuvB_N PF05496.7 EPE29001.1 - 0.033 13.2 0.1 0.065 12.2 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ResIII PF04851.10 EPE29001.1 - 0.047 13.5 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit cobW PF02492.14 EPE29001.1 - 0.048 13.1 0.1 0.098 12.0 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EPE29001.1 - 0.062 13.8 0.0 0.23 11.9 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein AAA_33 PF13671.1 EPE29001.1 - 0.077 12.8 0.7 0.44 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EPE29001.1 - 0.078 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 EPE29001.1 - 0.086 13.0 0.1 0.24 11.5 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EPE29001.1 - 0.087 12.5 0.2 0.28 10.8 0.1 1.8 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 EPE29001.1 - 0.089 12.9 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EPE29001.1 - 0.095 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Sulfatase PF00884.18 EPE29002.1 - 4.7e-64 216.4 0.1 6e-64 216.1 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EPE29002.1 - 0.012 14.9 0.0 0.28 10.4 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DPM3 PF08285.6 EPE29004.1 - 1e-32 111.8 0.2 1.1e-32 111.7 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Oxidored-like PF09791.4 EPE29005.1 - 1.4e-23 82.0 4.7 2.4e-23 81.2 3.2 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal MFS_1 PF07690.11 EPE29007.1 - 1.3e-35 122.7 43.6 1.2e-34 119.6 16.5 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE29007.1 - 1.7e-11 43.4 10.6 1.7e-11 43.4 7.4 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EPE29007.1 - 0.00059 18.0 0.6 0.00059 18.0 0.4 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector ABC2_membrane_5 PF13346.1 EPE29007.1 - 8.1 5.6 25.9 0.048 12.9 2.0 4.2 4 0 0 4 4 4 0 ABC-2 family transporter protein Pro_CA PF00484.14 EPE29008.1 - 8.9e-16 58.2 0.0 1.3e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase RRM_1 PF00076.17 EPE29009.1 - 6.9e-10 38.4 0.1 1.3e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE29009.1 - 1e-08 34.9 0.0 2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPE29009.1 - 0.0005 19.7 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EPE29009.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPE29009.1 - 0.0077 16.0 0.1 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif G-gamma PF00631.17 EPE29010.1 - 0.021 14.5 1.2 0.26 11.0 0.0 2.5 2 0 0 2 2 2 0 GGL domain Phage_lysis PF03245.8 EPE29010.1 - 0.026 14.5 0.7 0.026 14.5 0.5 1.8 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein ATG16 PF08614.6 EPE29010.1 - 0.12 12.2 3.4 0.15 11.8 0.2 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Striatin PF08232.7 EPE29010.1 - 0.21 11.9 5.1 1.5 9.1 1.0 2.3 2 0 0 2 2 2 0 Striatin family TSC22 PF01166.13 EPE29010.1 - 0.99 9.4 4.8 0.43 10.5 0.7 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Uds1 PF15456.1 EPE29010.1 - 1 9.3 7.7 0.29 11.1 1.3 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Rad10 PF03834.9 EPE29012.1 - 1.1e-30 105.1 0.1 1.7e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EPE29012.1 - 0.0017 18.4 0.0 0.0044 17.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Sipho_Gp37 PF14594.1 EPE29012.1 - 0.068 12.4 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein SLAC1 PF03595.12 EPE29013.1 - 1.5e-97 326.2 56.9 1.9e-97 325.9 39.5 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel SET PF00856.23 EPE29014.1 - 3.5e-06 27.4 1.4 2e-05 24.9 0.0 2.7 3 1 0 3 3 3 1 SET domain Ribosomal_L13e PF01294.13 EPE29015.1 - 5.2e-66 221.5 2.2 7.8e-66 220.9 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e N_methyl_2 PF13544.1 EPE29015.1 - 0.19 11.2 1.4 0.82 9.2 0.0 2.7 3 0 0 3 3 3 0 Type IV pilin N-term methylation site GFxxxE DUF1664 PF07889.7 EPE29017.1 - 0.82 9.4 6.5 0.094 12.5 0.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF1460 PF07313.7 EPE29018.1 - 0.098 11.8 0.1 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DUF4349 PF14257.1 EPE29018.1 - 0.4 9.8 11.6 0.051 12.8 1.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) FlbD PF06289.6 EPE29020.1 - 0.089 12.1 0.3 1.7 8.0 0.1 2.3 2 0 0 2 2 2 0 Flagellar protein (FlbD) IncA PF04156.9 EPE29021.1 - 0.00019 21.1 13.3 0.00019 21.1 9.2 2.2 2 1 1 3 3 3 1 IncA protein AAA_13 PF13166.1 EPE29021.1 - 0.027 12.9 6.0 0.037 12.5 4.1 1.2 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 EPE29021.1 - 0.031 13.4 2.2 0.12 11.5 1.1 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 EPE29021.1 - 0.032 14.1 3.7 0.032 14.1 2.6 3.1 3 0 0 3 3 3 0 bZIP transcription factor LYTB PF02401.13 EPE29021.1 - 0.23 10.3 1.9 3.3 6.5 0.1 2.1 1 1 1 2 2 2 0 LytB protein Cob_adeno_trans PF01923.13 EPE29021.1 - 0.35 10.6 4.4 0.45 10.2 2.1 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase TSC22 PF01166.13 EPE29021.1 - 0.52 10.3 11.3 1.5 8.8 0.1 2.7 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF972 PF06156.8 EPE29021.1 - 0.71 10.2 14.6 2.5 8.4 2.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 EPE29021.1 - 1.2 6.8 11.8 0.27 9.0 5.7 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.1 EPE29021.1 - 1.6 9.2 6.0 7.3 7.0 0.4 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 EPE29021.1 - 6.6 6.2 15.2 1.3 8.5 0.6 3.5 4 0 0 4 4 4 0 Septum formation initiator Sec2p PF06428.6 EPE29021.1 - 7.2 6.5 11.9 1.8 8.4 5.8 1.9 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p zf-RING_2 PF13639.1 EPE29022.1 - 3.1e-12 46.1 5.2 6.1e-12 45.1 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPE29022.1 - 1.1e-09 38.2 0.9 2.3e-09 37.2 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPE29022.1 - 1.4e-05 24.6 4.3 3e-05 23.5 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE29022.1 - 2.4e-05 24.2 5.5 4.9e-05 23.2 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE29022.1 - 5e-05 22.9 4.2 8.3e-05 22.2 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE29022.1 - 0.00012 21.7 3.2 0.00019 21.0 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPE29022.1 - 0.00025 20.8 1.5 0.0005 19.8 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2267 PF10025.4 EPE29022.1 - 0.0036 17.3 1.3 0.0073 16.3 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2267) zf-RING_UBOX PF13445.1 EPE29022.1 - 0.0042 16.7 1.7 0.0099 15.5 1.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger SDA1 PF05285.7 EPE29022.1 - 0.012 14.9 22.6 0.026 13.8 15.7 1.5 1 0 0 1 1 1 0 SDA1 zf-Nse PF11789.3 EPE29022.1 - 0.013 14.9 1.0 0.031 13.7 0.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EPE29022.1 - 0.042 13.7 5.3 0.18 11.7 3.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Tmpp129 PF10272.4 EPE29022.1 - 0.22 10.1 0.7 0.37 9.4 0.5 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor HgmA PF04209.8 EPE29024.1 - 2.1e-184 612.8 0.0 2.4e-184 612.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Fungal_trans PF04082.13 EPE29025.1 - 9.4e-18 64.0 0.0 1.9e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE29025.1 - 3.6e-08 33.1 13.9 6.3e-08 32.3 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 EPE29026.1 - 2e-54 184.8 0.1 2.3e-54 184.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPE29026.1 - 0.00058 19.9 0.0 0.031 14.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE29026.1 - 0.0029 17.6 0.1 0.0029 17.6 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPE29026.1 - 0.0039 16.9 0.4 0.4 10.4 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EPE29026.1 - 0.11 11.0 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Aldo_ket_red PF00248.16 EPE29028.1 - 1.9e-66 223.7 0.0 2.4e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 EPE29029.1 - 5.7e-60 203.1 0.0 6.4e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.13 EPE29030.1 - 1.2e-44 152.4 0.0 1.6e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EPE29030.1 - 4.6e-22 78.0 0.0 7.4e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal RCC1 PF00415.13 EPE29031.1 - 1.5e-52 175.6 4.8 3.8e-11 43.0 0.0 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPE29031.1 - 5.4e-32 108.7 28.2 6.7e-10 38.3 0.2 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat FUSC_2 PF13515.1 EPE29032.1 - 4.1e-14 52.5 30.7 6.1e-12 45.5 6.5 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like DUF2422 PF10337.4 EPE29032.1 - 4.2e-11 42.3 7.4 2.7e-07 29.7 1.8 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EPE29032.1 - 6.1e-08 32.5 0.0 4.5e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC PF04632.7 EPE29032.1 - 5e-05 21.9 12.0 5e-05 21.9 8.3 2.3 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF478 PF04334.7 EPE29032.1 - 1.3 8.9 8.4 0.67 9.8 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF478) ALMT PF11744.3 EPE29032.1 - 1.9 7.0 13.3 0.0054 15.4 2.2 1.8 2 0 0 2 2 2 0 Aluminium activated malate transporter SIR2 PF02146.12 EPE29033.1 - 1.5e-57 194.2 0.0 2.2e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EPE29033.1 - 9.5e-05 21.9 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EPE29033.1 - 0.0041 16.8 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Ribosomal_L34e PF01199.13 EPE29033.1 - 0.045 13.9 1.6 0.091 12.9 1.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L34e HET PF06985.6 EPE29034.1 - 1.6e-20 73.6 0.0 3.3e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SRR1 PF07985.7 EPE29035.1 - 0.0038 17.1 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 SRR1 E1-E2_ATPase PF00122.15 EPE29037.1 - 1.8e-57 194.0 0.9 1.8e-57 194.0 0.6 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPE29037.1 - 1.2e-42 145.4 8.1 1.2e-42 145.4 5.6 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPE29037.1 - 2.3e-27 96.8 0.4 5e-27 95.7 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPE29037.1 - 8.9e-21 73.6 0.0 1.9e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPE29037.1 - 1.6e-13 51.2 0.0 4.1e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPE29037.1 - 1.8e-06 27.7 0.4 9.4e-05 22.0 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPE29037.1 - 3.8e-05 23.0 0.1 0.00045 19.6 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF3500 PF12006.3 EPE29037.1 - 0.0055 15.6 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) DevR PF01905.11 EPE29037.1 - 0.054 12.3 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 DUF2976 PF11190.3 EPE29037.1 - 2.3 7.8 8.4 0.22 11.0 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) ESSS PF10183.4 EPE29038.1 - 8.4e-29 100.0 0.3 9.9e-29 99.8 0.2 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Aminotran_4 PF01063.14 EPE29039.1 - 4.1e-29 101.6 0.0 5.5e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 EPE29040.1 - 4.9e-18 65.2 0.0 1.2e-17 63.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29040.1 - 1.9e-08 33.7 0.0 1.1e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase bZIP_2 PF07716.10 EPE29043.1 - 0.056 13.2 8.7 0.13 12.1 0.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.16 EPE29043.1 - 0.5 10.3 6.3 2.8 7.9 1.7 2.2 2 0 0 2 2 2 0 bZIP transcription factor MFS_1 PF07690.11 EPE29044.1 - 3.4e-19 68.7 44.6 1.6e-10 40.2 14.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EPE29044.1 - 0.016 15.0 1.3 0.074 12.8 0.0 2.8 3 0 0 3 3 3 0 MFS_1 like family BatA PF07584.6 EPE29044.1 - 0.035 14.2 0.1 0.22 11.7 0.1 2.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal NAD_binding_6 PF08030.7 EPE29044.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Rhodanese PF00581.15 EPE29045.1 - 2e-06 28.1 0.0 4e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain SBF PF01758.11 EPE29046.1 - 2.1e-51 174.0 9.8 2.1e-51 174.0 6.8 2.3 4 0 0 4 4 4 1 Sodium Bile acid symporter family PRKCSH-like PF12999.2 EPE29047.1 - 1.1e-45 155.3 3.4 1.6e-26 92.9 0.1 2.8 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EPE29047.1 - 1.2e-28 99.5 4.5 2e-28 98.8 0.7 2.6 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EPE29047.1 - 1.1e-09 38.9 3.1 1.1e-09 38.9 2.1 2.3 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein RILP PF11461.3 EPE29047.1 - 0.014 15.5 0.8 0.039 14.1 0.6 1.8 1 0 0 1 1 1 0 Rab interacting lysosomal protein Snapin_Pallidin PF14712.1 EPE29047.1 - 0.015 15.5 1.3 0.45 10.8 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin ydhR PF08803.6 EPE29047.1 - 0.076 13.0 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR IncA PF04156.9 EPE29047.1 - 0.091 12.3 4.5 0.44 10.1 3.1 2.0 1 1 0 1 1 1 0 IncA protein Sec2p PF06428.6 EPE29047.1 - 0.12 12.2 2.4 5.6 6.8 0.1 3.2 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p CASP_C PF08172.7 EPE29047.1 - 0.13 11.2 1.4 0.23 10.4 1.0 1.3 1 0 0 1 1 1 0 CASP C terminal Prefoldin_2 PF01920.15 EPE29047.1 - 0.36 10.6 3.9 0.77 9.5 0.2 2.6 2 0 0 2 2 2 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.4 EPE29047.1 - 0.39 10.7 5.8 0.18 11.7 1.3 2.5 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Ldl_recept_a PF00057.13 EPE29047.1 - 0.46 10.4 9.2 0.17 11.8 1.2 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Rtf2 PF04641.7 EPE29051.1 - 2.6e-59 200.5 2.2 3.3e-59 200.2 1.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EPE29051.1 - 2.8e-06 26.7 0.1 0.0013 18.2 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EPE29051.1 - 0.00019 21.0 0.2 0.0005 19.7 0.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EPE29051.1 - 0.049 13.4 0.2 0.84 9.5 0.3 2.3 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 EPE29051.1 - 0.076 12.7 0.1 0.27 10.9 0.1 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE29051.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-TFIIIC PF12660.2 EPE29051.1 - 0.13 12.1 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex Plasmodium_Vir PF05795.6 EPE29051.1 - 0.28 10.3 3.7 0.44 9.7 2.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAT PF02259.18 EPE29052.1 - 1.1e-126 422.6 2.5 2.4e-126 421.4 1.7 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EPE29052.1 - 4.5e-60 203.0 0.3 1.4e-59 201.3 0.2 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EPE29052.1 - 2.7e-58 196.4 4.7 7.8e-57 191.6 0.6 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EPE29052.1 - 2.3e-41 139.9 3.6 3.2e-41 139.4 0.0 3.2 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EPE29052.1 - 1.5e-19 70.0 11.4 0.00036 20.7 0.1 9.8 4 3 6 10 10 10 6 HEAT repeats HEAT PF02985.17 EPE29052.1 - 3.9e-17 60.7 20.5 0.00033 20.4 0.0 12.8 13 0 0 13 13 12 2 HEAT repeat FATC PF02260.15 EPE29052.1 - 6.1e-11 41.5 0.1 1.4e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 EPE29052.1 - 1.7e-10 41.0 16.0 0.00018 21.8 0.0 11.7 10 3 3 13 13 12 2 HEAT-like repeat Adaptin_N PF01602.15 EPE29052.1 - 3.1e-06 25.7 9.7 0.0004 18.8 0.1 4.5 4 1 0 4 4 4 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EPE29052.1 - 2.3e-05 24.7 1.1 45 4.5 0.0 7.4 7 2 1 8 8 7 0 Vacuolar 14 Fab1-binding region UME PF08064.8 EPE29052.1 - 5.2e-05 23.1 5.3 0.1 12.5 0.2 6.2 7 0 0 7 7 6 1 UME (NUC010) domain CLASP_N PF12348.3 EPE29052.1 - 0.00061 19.2 0.0 1 8.6 0.0 4.9 4 1 0 4 4 4 1 CLASP N terminal Apc3 PF12895.2 EPE29052.1 - 0.0035 17.4 1.9 5.5 7.1 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EPE29052.1 - 1.1 9.2 4.3 4.4 7.3 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat adh_short_C2 PF13561.1 EPE29053.1 - 4.3e-28 98.7 0.0 5.4e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE29053.1 - 4.1e-26 91.8 0.4 6.9e-26 91.1 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE29053.1 - 5.6e-13 48.9 0.3 9.6e-13 48.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE29053.1 - 0.0018 17.7 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPE29053.1 - 0.012 14.5 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pam16 PF03656.8 EPE29054.1 - 3.1e-35 120.7 1.1 4.1e-35 120.3 0.7 1.1 1 0 0 1 1 1 1 Pam16 14-3-3 PF00244.15 EPE29055.1 - 3.7e-114 379.7 1.4 4.8e-114 379.3 1.0 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EPE29055.1 - 0.011 15.2 0.3 5.2 6.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF837) DUF4085 PF13315.1 EPE29055.1 - 0.019 14.3 0.2 0.03 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) TPR_12 PF13424.1 EPE29055.1 - 0.041 13.8 0.2 8.4 6.4 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat MCM_N PF14551.1 EPE29055.1 - 0.95 9.9 2.9 14 6.2 2.0 2.3 1 1 0 1 1 1 0 MCM N-terminal domain Suf PF05843.9 EPE29057.1 - 4.8e-05 23.2 9.1 0.002 17.9 0.0 3.2 2 1 0 3 3 3 2 Suppressor of forked protein (Suf) SNAP PF14938.1 EPE29057.1 - 0.0011 18.2 1.3 0.0025 17.0 0.5 1.8 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 EPE29057.1 - 0.021 15.4 2.2 6.8 7.6 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPE29057.1 - 0.048 14.3 0.2 51 4.7 0.0 3.8 2 1 0 3 3 3 0 Tetratricopeptide repeat HET PF06985.6 EPE29058.1 - 1.8e-23 83.2 0.3 3.3e-23 82.3 0.0 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF781 PF05612.7 EPE29058.1 - 0.0083 14.8 0.1 0.014 14.1 0.1 1.2 1 0 0 1 1 1 1 Mouse protein of unknown function (DUF781) zf-RING_2 PF13639.1 EPE29060.1 - 6.2e-13 48.3 2.1 6.2e-13 48.3 1.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EPE29060.1 - 1.1e-09 38.2 1.5 1.1e-09 38.2 1.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPE29060.1 - 4.9e-08 32.5 1.4 4.9e-08 32.5 1.0 2.2 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE29060.1 - 1.8e-05 24.3 3.4 1.8e-05 24.3 2.4 2.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE29060.1 - 2.4e-05 24.2 4.5 2.4e-05 24.2 3.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE29060.1 - 0.0006 19.4 3.6 0.0006 19.4 2.5 2.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPE29060.1 - 0.0033 17.2 3.0 0.0033 17.2 2.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EPE29060.1 - 0.0057 16.4 0.3 0.02 14.6 0.2 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EPE29060.1 - 0.027 14.2 1.1 0.23 11.2 0.1 2.6 1 1 1 2 2 2 0 RING-type zinc-finger zf-P11 PF03854.9 EPE29060.1 - 0.049 13.1 1.2 0.086 12.3 0.1 1.9 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4_4 PF15227.1 EPE29060.1 - 0.2 11.5 4.3 0.13 12.1 0.9 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EPE29060.1 - 0.71 9.4 5.8 0.062 12.8 0.4 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EPE29060.1 - 2.1 8.3 6.5 1.6 8.7 2.0 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain zf-rbx1 PF12678.2 EPE29061.1 - 9.5e-09 35.2 0.4 9.5e-09 35.2 0.3 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPE29061.1 - 8.9e-08 31.8 2.5 8.9e-08 31.8 1.8 3.1 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EPE29061.1 - 1.3e-06 28.0 1.1 1.3e-06 28.0 0.8 3.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPE29061.1 - 1.6e-06 27.8 0.3 1.6e-06 27.8 0.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EPE29061.1 - 1.6e-05 24.4 0.8 1.6e-05 24.4 0.6 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE29061.1 - 0.00027 20.9 1.6 0.00027 20.9 1.1 4.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE29061.1 - 0.0068 16.0 2.9 0.0068 16.0 2.0 3.0 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPE29061.1 - 0.028 14.1 3.3 0.13 12.0 0.5 2.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EPE29061.1 - 0.053 13.4 0.3 0.053 13.4 0.2 2.8 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-Sec23_Sec24 PF04810.10 EPE29061.1 - 0.39 10.3 2.2 15 5.2 0.1 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger RhoGAP PF00620.22 EPE29062.1 - 9e-42 142.2 0.0 2.3e-41 140.9 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 EPE29062.1 - 4.7e-09 36.3 0.0 1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EPE29062.1 - 5.5e-08 33.0 0.0 1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3450 PF11932.3 EPE29062.1 - 0.0096 15.2 0.3 0.018 14.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) zf-RING_2 PF13639.1 EPE29064.1 - 4.6e-11 42.3 5.5 4.6e-11 42.3 3.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE29064.1 - 2.2e-05 24.3 5.2 2.2e-05 24.3 3.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE29064.1 - 6.4e-05 22.5 3.7 6.4e-05 22.5 2.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE29064.1 - 0.0001 22.3 1.1 0.0001 22.3 0.7 2.3 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPE29064.1 - 0.036 13.7 7.9 0.038 13.7 3.3 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE29064.1 - 0.081 12.5 8.7 0.032 13.8 3.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPE29064.1 - 0.47 10.3 2.6 1.9 8.4 1.8 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EPE29064.1 - 0.59 9.7 3.7 1.6 8.3 2.5 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2358 PF10184.4 EPE29065.1 - 0.061 13.2 0.9 0.2 11.5 0.6 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) zf-RING_2 PF13639.1 EPE29066.1 - 9.8e-14 50.9 8.6 9.8e-14 50.9 5.9 2.0 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EPE29066.1 - 1.7e-09 37.6 3.6 3.3e-09 36.7 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPE29066.1 - 1.5e-06 27.8 7.1 1.5e-06 27.8 4.9 2.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE29066.1 - 4e-05 23.1 7.9 4e-05 23.1 5.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE29066.1 - 0.00011 22.1 8.6 0.00011 22.1 6.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE29066.1 - 0.00012 21.6 6.3 0.00012 21.6 4.4 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPE29066.1 - 0.00018 21.2 2.2 0.0005 19.8 1.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SIP1 PF04938.7 EPE29066.1 - 0.0066 15.8 1.5 0.0097 15.2 1.0 1.4 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Prok-RING_4 PF14447.1 EPE29066.1 - 0.0073 15.8 4.8 0.027 14.0 3.3 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.9 EPE29066.1 - 0.013 14.9 1.2 5.8 6.4 0.0 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 EPE29066.1 - 0.023 14.4 4.5 0.046 13.4 2.3 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EPE29066.1 - 0.064 12.8 6.2 0.13 11.8 4.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EPE29066.1 - 0.073 12.9 0.5 0.17 11.7 0.4 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-Nse PF11789.3 EPE29066.1 - 0.13 11.8 3.2 0.31 10.5 2.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EPE29066.1 - 1.8 8.4 12.4 0.98 9.3 5.9 2.5 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EPE29066.1 - 2.3 8.0 6.4 0.32 10.7 0.7 2.2 2 1 1 3 3 3 0 zf-RING of BARD1-type protein F-box PF00646.28 EPE29067.1 - 0.0035 16.9 0.0 0.0087 15.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE29067.1 - 0.018 14.7 2.0 0.057 13.1 0.0 2.7 3 0 0 3 3 3 0 F-box-like zf-RING_2 PF13639.1 EPE29068.1 - 8.6e-06 25.4 10.6 8.6e-06 25.4 7.3 2.4 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EPE29068.1 - 1.5e-05 24.9 3.3 1.5e-05 24.9 2.3 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPE29068.1 - 0.00035 20.1 8.3 0.00042 19.9 3.3 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPE29068.1 - 0.0013 18.5 0.6 0.0035 17.1 0.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EPE29068.1 - 0.015 15.0 6.5 0.015 15.0 4.5 2.7 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_2 PF13639.1 EPE29069.1 - 3.7e-10 39.4 6.4 3.7e-10 39.4 4.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EPE29069.1 - 5.4e-08 32.8 3.2 1.4e-07 31.5 2.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EPE29069.1 - 1.8e-05 24.2 3.6 1.8e-05 24.2 2.5 2.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE29069.1 - 2.3e-05 24.3 0.3 2.3e-05 24.3 0.2 3.2 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE29069.1 - 4.2e-05 23.1 3.6 4.2e-05 23.1 2.5 2.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPE29069.1 - 0.00013 21.6 3.2 0.00043 19.9 0.0 3.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EPE29069.1 - 0.00016 21.2 1.4 0.00016 21.2 1.0 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EPE29069.1 - 0.00025 20.5 0.4 0.00081 18.8 0.3 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EPE29069.1 - 0.0067 16.2 0.6 0.0067 16.2 0.4 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPE29069.1 - 0.032 13.7 1.9 0.2 11.2 1.3 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EPE29069.1 - 0.041 13.7 1.4 0.11 12.3 1.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 EPE29069.1 - 0.053 12.9 0.1 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif FANCL_C PF11793.3 EPE29069.1 - 0.19 11.7 2.9 0.82 9.6 2.0 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain HET PF06985.6 EPE29070.1 - 1.2e-24 87.0 0.5 2e-24 86.3 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DnaJ PF00226.26 EPE29071.1 - 2.2e-11 43.2 0.2 2.2e-11 43.2 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain PRA1 PF03208.14 EPE29072.1 - 3e-39 133.8 0.1 3.7e-39 133.5 0.1 1.0 1 0 0 1 1 1 1 PRA1 family protein DnaJ PF00226.26 EPE29074.1 - 4e-21 74.5 1.7 7.7e-21 73.6 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EPE29074.1 - 0.02 14.9 0.2 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 EPE29074.1 - 0.055 13.1 0.5 0.14 11.8 0.4 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Nucleoporin_FG PF13634.1 EPE29075.1 - 0.0021 18.2 9.2 0.0034 17.5 6.4 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeat region FAA_hydrolase PF01557.13 EPE29076.1 - 2.2e-60 203.8 0.0 3e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.10 EPE29077.1 - 1.6e-13 50.2 0.9 4.6e-13 48.7 0.6 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPE29077.1 - 1.8e-10 40.8 1.0 5.3e-10 39.3 0.7 1.8 1 0 0 1 1 1 1 Complex1_LYR-like TMEM223 PF14640.1 EPE29077.1 - 0.096 12.6 0.1 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 223 BTB PF00651.26 EPE29078.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Lipase_3 PF01764.20 EPE29082.1 - 1.6e-28 99.1 0.0 2.3e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 EPE29082.1 - 0.0072 16.5 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EPE29082.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE29082.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_trans_1_4 PF13692.1 EPE29082.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Lipase PF00151.14 EPE29082.1 - 0.026 13.7 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Lipase DUF2974 PF11187.3 EPE29082.1 - 0.058 12.7 0.1 0.51 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EPE29082.1 - 0.22 11.1 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein HATPase_c PF02518.21 EPE29083.1 - 3.6e-19 68.5 0.0 1.8e-17 63.0 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE29083.1 - 3.9e-14 52.6 0.1 1e-13 51.2 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EPE29083.1 - 8e-05 22.5 0.0 0.00033 20.5 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EPE29083.1 - 0.011 15.3 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.1 EPE29083.1 - 0.032 14.7 0.0 0.086 13.3 0.0 1.7 1 0 0 1 1 1 0 GAF domain Syja_N PF02383.13 EPE29084.1 - 5.9e-84 281.5 0.0 1.2e-83 280.5 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EPE29084.1 - 6.1e-22 78.7 0.0 1.3e-21 77.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 EPE29085.1 - 1.9e-10 40.0 44.3 3e-09 36.0 25.7 3.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPE29085.1 - 0.00022 19.5 14.1 0.00046 18.5 9.7 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BRI3BP PF14965.1 EPE29085.1 - 0.038 13.3 0.1 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 Negative regulator of p53/TP53 His_Phos_1 PF00300.17 EPE29086.1 - 9.2e-15 55.0 0.0 2.2e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CBM_5_12_2 PF14600.1 EPE29087.1 - 0.017 14.7 0.0 0.045 13.3 0.0 1.7 1 0 0 1 1 1 0 Cellulose-binding domain PTR2 PF00854.16 EPE29088.1 - 1.5e-42 145.7 12.1 3.9e-42 144.3 8.4 1.7 1 1 0 1 1 1 1 POT family AMP-binding PF00501.23 EPE29089.1 - 2.6e-92 309.3 0.0 3.1e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE29089.1 - 2.2e-14 54.1 0.3 5.8e-14 52.8 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ATP11 PF06644.6 EPE29090.1 - 2e-90 302.9 0.0 2.3e-90 302.7 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein DUF1018 PF06252.7 EPE29090.1 - 0.053 14.0 0.3 0.18 12.3 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1018) RHH_1 PF01402.16 EPE29090.1 - 0.072 13.0 1.5 0.4 10.6 0.4 2.7 1 1 1 2 2 2 0 Ribbon-helix-helix protein, copG family Cas_Cas02710 PF09670.5 EPE29090.1 - 0.079 11.5 0.1 0.13 10.8 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Proteasome PF00227.21 EPE29091.1 - 1.2e-44 151.8 0.1 2.7e-31 108.3 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EPE29091.1 - 1.3e-11 43.6 0.0 3.6e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature S-methyl_trans PF02574.11 EPE29093.1 - 4.3e-24 85.3 0.0 6.1e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Mit_KHE1 PF10173.4 EPE29093.1 - 0.12 12.2 0.1 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related RTA1 PF04479.8 EPE29094.1 - 5.5e-44 150.3 6.9 8.5e-44 149.7 4.8 1.2 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.3 EPE29094.1 - 0.00086 18.0 0.4 0.0018 16.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE29094.1 - 0.0033 17.2 1.3 0.0064 16.3 0.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.26 EPE29097.1 - 3e-10 40.0 0.0 5.3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EPE29098.1 - 0.00015 21.6 0.1 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EPE29100.1 - 0.0078 16.1 0.1 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 EPE29103.1 - 4.4e-80 260.9 27.7 2.2e-13 49.4 1.3 8.7 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EPE29103.1 - 9.3e-11 41.7 0.4 0.00051 19.7 0.0 4.0 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPE29103.1 - 2.7e-09 35.7 8.2 0.0014 16.8 0.4 4.9 3 1 2 5 5 5 4 Nucleoporin Nup120/160 NLE PF08154.7 EPE29103.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 EPE29103.1 - 0.013 15.4 0.2 1.3 9.0 0.0 2.8 2 1 0 2 2 2 0 Siderophore-interacting FAD-binding domain PD40 PF07676.7 EPE29103.1 - 0.055 13.1 0.3 37 4.1 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 EPE29103.1 - 0.2 12.0 2.1 1.3 9.3 0.3 3.3 4 0 0 4 4 4 0 PQQ-like domain MutS_V PF00488.16 EPE29104.1 - 1.2e-74 250.6 0.1 1.8e-74 250.0 0.1 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPE29104.1 - 3.2e-28 98.9 2.9 9.8e-27 94.0 0.4 2.7 2 1 0 2 2 2 2 MutS domain III MutS_II PF05188.12 EPE29104.1 - 1.5e-09 38.0 0.0 9.1e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EPE29104.1 - 1e-06 28.8 0.2 2.2e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV Cyclin PF08613.6 EPE29105.1 - 4e-38 131.1 1.7 2.4e-22 79.9 0.1 2.9 3 0 0 3 3 3 2 Cyclin DUF605 PF04652.11 EPE29105.1 - 9.6 5.4 23.9 6.7 6.0 13.1 2.3 2 0 0 2 2 2 0 Vta1 like Proteasome PF00227.21 EPE29107.1 - 2.3e-48 164.0 0.2 2.6e-48 163.8 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Evr1_Alr PF04777.8 EPE29108.1 - 1e-28 99.0 0.2 1.6e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Aminotran_4 PF01063.14 EPE29109.1 - 7.7e-25 87.7 0.0 1e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV BTB PF00651.26 EPE29112.1 - 0.0057 16.6 0.0 0.013 15.4 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain SLD3 PF08639.5 EPE29113.1 - 0.054 12.1 0.2 0.059 11.9 0.1 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 CAP PF00188.21 EPE29114.1 - 9.7e-21 74.5 1.2 1.4e-20 73.9 0.8 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_transf_20 PF00982.16 EPE29115.1 - 2.7e-164 547.1 0.2 3.6e-164 546.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPE29115.1 - 3.2e-48 163.6 0.0 5.5e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EPE29115.1 - 6.4e-05 22.6 0.0 0.034 13.7 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase DUF718 PF05336.8 EPE29115.1 - 0.11 12.2 5.6 1.4 8.7 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF718) AAA PF00004.24 EPE29116.1 - 5.7e-12 45.9 0.1 6.9e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF221 PF02714.10 EPE29117.1 - 3.3e-99 331.8 18.9 4.7e-99 331.3 13.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPE29117.1 - 3.7e-43 146.7 0.3 3.7e-43 146.7 0.2 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EPE29117.1 - 9e-21 74.1 0.4 2e-20 73.1 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 EPE29117.1 - 0.00026 19.7 0.8 0.00047 18.9 0.5 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel F-box-like PF12937.2 EPE29117.1 - 0.026 14.2 0.1 0.026 14.2 0.1 2.8 3 0 0 3 3 3 0 F-box-like GATase PF00117.23 EPE29118.1 - 1.1e-09 38.0 0.0 1.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPE29118.1 - 5.4e-05 22.7 0.2 0.00014 21.3 0.2 1.7 1 1 0 1 1 1 1 Peptidase C26 DUF4078 PF13300.1 EPE29118.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) ADH_zinc_N PF00107.21 EPE29120.1 - 2.9e-12 46.2 0.0 5.9e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE29120.1 - 1.6e-06 27.8 0.8 1.4e-05 24.8 0.2 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPE29120.1 - 0.00016 22.6 0.0 0.00034 21.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase MAPEG PF01124.13 EPE29121.1 - 2.3e-16 59.5 0.2 3e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 MAPEG family DUF1772 PF08592.6 EPE29121.1 - 0.012 15.3 0.3 0.024 14.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) BTP PF05232.7 EPE29121.1 - 1.3 8.7 4.8 2.7 7.7 0.2 2.4 3 0 0 3 3 3 0 Bacterial Transmembrane Pair family HET PF06985.6 EPE29122.1 - 2.4e-24 86.0 0.0 4.7e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 EPE29124.1 - 3e-74 250.2 0.0 3.8e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EPE29124.1 - 1.6e-30 106.1 0.1 2.8e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EPE29124.1 - 1.7e-22 79.9 0.0 2.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EPE29124.1 - 7.4e-12 45.8 0.0 1.7e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EPE29124.1 - 0.0018 18.2 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.6 EPE29124.1 - 0.0024 17.7 0.0 0.0086 15.9 0.0 1.9 2 0 0 2 2 2 1 NrdI Flavodoxin like KAR9 PF08580.5 EPE29125.1 - 7.9e-127 424.3 16.9 7.9e-127 424.3 11.7 1.7 2 0 0 2 2 2 1 Yeast cortical protein KAR9 THOC7 PF05615.8 EPE29125.1 - 0.067 13.4 3.9 1.4 9.1 0.1 2.9 3 0 0 3 3 3 0 Tho complex subunit 7 Prefoldin_2 PF01920.15 EPE29125.1 - 0.31 10.8 6.8 2.3 8.0 0.1 3.7 3 0 0 3 3 3 0 Prefoldin subunit DUF4047 PF13256.1 EPE29125.1 - 0.55 10.1 3.6 5 7.1 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Syntaxin-6_N PF09177.6 EPE29125.1 - 2.8 8.4 11.6 13 6.2 0.6 4.8 2 2 0 4 4 4 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 EPE29125.1 - 8.7 6.3 11.0 24 4.9 0.3 4.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF706 PF05153.10 EPE29126.1 - 4.8e-129 429.0 1.4 6.1e-129 428.7 1.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EPE29126.1 - 0.03 14.3 0.1 0.51 10.3 0.0 2.5 3 0 0 3 3 3 0 HD domain F-box-like PF12937.2 EPE29127.1 - 0.0024 17.5 0.2 0.01 15.5 0.1 2.1 1 1 0 1 1 1 1 F-box-like AOX PF01786.12 EPE29129.1 - 1.1e-87 292.7 0.1 1.4e-87 292.4 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF726 PF05277.7 EPE29130.1 - 6.2e-125 416.6 1.7 9e-125 416.1 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EPE29130.1 - 0.022 14.5 0.6 0.18 11.5 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Fcf1 PF04900.7 EPE29131.1 - 9.3e-24 83.4 0.0 1.8e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Fcf1 Peptidase_C57 PF03290.8 EPE29131.1 - 0.17 10.3 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase zf-CCHC PF00098.18 EPE29133.1 - 4.4e-05 23.1 0.8 4.4e-05 23.1 0.6 4.3 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_4 PF14392.1 EPE29133.1 - 0.00024 20.6 24.1 0.18 11.4 0.4 4.7 4 0 0 4 4 4 4 Zinc knuckle SPATA24 PF15175.1 EPE29133.1 - 0.00047 19.8 0.4 0.0024 17.5 0.2 2.2 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 DUF3425 PF11905.3 EPE29134.1 - 1.6e-30 105.7 0.0 3.1e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.20 EPE29135.1 - 2.3e-16 60.1 0.0 4e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE29135.1 - 5.4e-06 26.1 0.0 1.3e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EPE29135.1 - 0.0014 18.0 0.1 0.0037 16.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPE29135.1 - 0.0015 17.4 0.0 0.002 17.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.8 EPE29135.1 - 0.0035 16.7 0.0 0.82 9.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase WecB/TagA/CpsF family Methyltransf_25 PF13649.1 EPE29135.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 EPE29135.1 - 0.13 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_N PF08240.7 EPE29136.1 - 1.1e-27 95.9 1.5 1.4e-27 95.6 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE29136.1 - 3.7e-20 71.7 0.4 5.8e-20 71.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EPE29136.1 - 0.0012 18.2 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EPE29136.1 - 0.0016 18.2 0.1 0.0038 17.0 0.1 1.6 1 0 0 1 1 1 1 ThiF family Methyltransf_18 PF12847.2 EPE29136.1 - 0.0058 17.1 0.1 0.012 16.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.13 EPE29136.1 - 0.014 15.0 0.7 0.023 14.3 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EPE29136.1 - 0.093 11.5 0.2 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EPE29136.1 - 0.1 11.0 0.5 0.15 10.4 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 EPE29136.1 - 0.13 11.4 0.1 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EPE29136.1 - 0.19 12.0 1.1 0.47 10.7 0.8 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.20 EPE29139.1 - 6.4e-33 114.0 0.3 8.1e-33 113.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE29139.1 - 2.5e-23 83.1 0.0 3.1e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE29139.1 - 1.1e-14 54.5 0.5 2e-14 53.6 0.4 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE29139.1 - 7.8e-08 32.0 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPE29139.1 - 6.5e-05 22.6 0.2 0.00013 21.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 EPE29139.1 - 0.033 13.7 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EPE29139.1 - 0.076 13.2 0.1 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.11 EPE29139.1 - 0.078 12.4 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DEAD PF00270.24 EPE29141.1 - 9.6e-24 83.7 0.0 2.8e-23 82.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE29141.1 - 7.8e-21 73.7 1.0 3.3e-18 65.3 0.0 3.4 3 1 0 3 3 3 2 Helicase conserved C-terminal domain RQC PF09382.5 EPE29141.1 - 6.1e-18 64.4 1.1 1.1e-17 63.6 0.1 2.0 2 0 0 2 2 2 1 RQC domain ResIII PF04851.10 EPE29141.1 - 0.00017 21.5 0.0 0.00058 19.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MFS_1 PF07690.11 EPE29142.1 - 5.3e-29 101.0 13.3 7.8e-29 100.4 9.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.14 EPE29142.1 - 1.4 7.4 14.4 0.051 12.1 2.9 2.6 3 0 0 3 3 3 0 LacY proton/sugar symporter GPI-anchored PF10342.4 EPE29143.1 - 2.2e-18 66.5 0.7 2.2e-18 66.5 0.5 2.9 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ABC_membrane PF00664.18 EPE29144.1 - 4.1e-64 216.6 41.7 5e-35 121.2 12.2 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EPE29144.1 - 4.3e-63 211.6 0.0 3.9e-31 108.1 0.0 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPE29144.1 - 3.1e-12 46.1 4.5 0.00053 19.2 1.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE29144.1 - 6.6e-12 45.9 0.4 0.00079 19.4 0.1 4.1 2 2 1 3 3 3 3 AAA domain AAA_16 PF13191.1 EPE29144.1 - 9.1e-09 35.5 0.6 8.7e-05 22.5 0.0 3.1 4 0 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 EPE29144.1 - 1.3e-08 35.0 0.2 0.013 15.6 0.0 3.9 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EPE29144.1 - 1.7e-08 33.5 0.0 0.0072 14.9 0.0 3.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EPE29144.1 - 4.3e-08 34.0 0.1 0.006 17.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPE29144.1 - 5.4e-08 32.2 0.5 0.0005 19.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPE29144.1 - 1.6e-07 30.6 0.0 0.01 15.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EPE29144.1 - 6.3e-06 26.6 0.1 0.019 15.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EPE29144.1 - 0.00012 21.7 0.4 0.94 9.0 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EPE29144.1 - 0.00018 20.9 0.2 0.95 8.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EPE29144.1 - 0.00028 21.2 0.2 0.13 12.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPE29144.1 - 0.00073 19.2 0.0 0.68 9.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EPE29144.1 - 0.00086 19.2 0.0 4.2 7.2 0.0 3.8 4 0 0 4 4 3 1 AAA domain SbcCD_C PF13558.1 EPE29144.1 - 0.00096 19.0 1.4 0.74 9.7 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EPE29144.1 - 0.0015 18.0 0.1 0.55 9.6 0.0 3.6 3 0 0 3 3 3 1 AAA-like domain AAA PF00004.24 EPE29144.1 - 0.0015 18.6 1.5 0.53 10.4 0.2 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 EPE29144.1 - 0.0022 17.5 0.3 0.69 9.3 0.1 2.6 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 EPE29144.1 - 0.0036 16.4 0.1 0.47 9.4 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EPE29144.1 - 0.0052 16.7 0.0 3.8 7.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EPE29144.1 - 0.0057 16.2 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein PRK PF00485.13 EPE29144.1 - 0.018 14.6 0.0 5.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EPE29144.1 - 0.019 14.8 0.0 3.6 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.1 EPE29144.1 - 0.038 12.5 0.1 1.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) RNA_helicase PF00910.17 EPE29144.1 - 0.1 12.8 0.1 26 5.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase DUF2098 PF09871.4 EPE29144.1 - 2.1 8.3 6.3 1.6 8.7 0.6 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) TRP PF06011.7 EPE29145.1 - 5.2e-129 430.6 15.8 6.9e-129 430.2 10.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPE29145.1 - 4.8e-37 127.1 4.2 4.8e-37 127.1 2.9 1.6 2 0 0 2 2 2 1 ML-like domain MscL PF01741.13 EPE29145.1 - 0.045 13.9 2.5 0.082 13.0 0.2 2.3 2 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL TMEM154 PF15102.1 EPE29145.1 - 1.6 8.4 6.4 9.3 5.9 1.8 2.7 2 0 0 2 2 2 0 TMEM154 protein family CRT10 PF08728.5 EPE29147.1 - 6e-14 51.0 0.0 2.5e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 CRT10 Ammonium_transp PF00909.16 EPE29148.1 - 4.5e-116 387.6 29.4 5.2e-116 387.4 20.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Sugar_tr PF00083.19 EPE29153.1 - 2.1e-123 412.2 26.7 2.4e-123 412.0 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE29153.1 - 3.7e-16 58.8 31.2 1.5e-10 40.3 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_35 PF01301.14 EPE29153.1 - 0.078 12.3 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 NUMOD1 PF07453.8 EPE29154.1 - 0.03 14.1 0.9 1.2 9.0 0.1 3.0 2 1 1 3 3 3 0 NUMOD1 domain Kelch_6 PF13964.1 EPE29156.1 - 0.00013 21.9 1.1 2.8 8.2 0.0 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 EPE29156.1 - 0.039 13.9 0.1 0.99 9.4 0.0 3.2 4 0 0 4 4 4 0 Kelch motif HLH PF00010.21 EPE29158.1 - 5.4e-16 58.0 0.0 1.4e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IncA PF04156.9 EPE29158.1 - 0.52 9.8 7.1 0.49 9.9 1.1 2.4 2 0 0 2 2 2 0 IncA protein Pcc1 PF09341.5 EPE29159.1 - 3e-25 88.0 0.2 3.8e-25 87.7 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.1 EPE29160.1 - 2.9e-43 147.2 0.0 1.5e-39 135.1 0.0 3.3 3 0 0 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EPE29160.1 - 1e-15 57.5 0.0 2.1e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPE29160.1 - 1.4e-05 24.6 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EPE29160.1 - 0.078 13.0 0.1 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EPE29160.1 - 0.13 12.5 0.1 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.7 EPE29160.1 - 0.17 11.3 0.1 0.43 10.0 0.1 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) 14-3-3 PF00244.15 EPE29161.1 - 9.1e-117 388.2 6.5 1.1e-116 388.0 4.5 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_M17_N PF02789.12 EPE29161.1 - 0.0059 16.3 0.3 0.034 13.8 0.0 2.3 2 1 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain TPR_19 PF14559.1 EPE29161.1 - 0.31 11.4 3.1 2.5 8.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3461 PF11944.3 EPE29161.1 - 2.9 7.7 6.1 2 8.2 0.3 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3461) IATP PF04568.7 EPE29163.1 - 5.3e-23 80.9 1.0 6.1e-23 80.7 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Atg14 PF10186.4 EPE29163.1 - 0.04 12.8 0.5 0.037 12.9 0.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3233 PF11557.3 EPE29163.1 - 0.048 12.4 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3233) Fib_alpha PF08702.5 EPE29163.1 - 0.094 12.8 0.2 0.12 12.4 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MutS_III PF05192.13 EPE29163.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 MutS domain III SseC PF04888.7 EPE29163.1 - 0.14 11.4 2.0 0.2 10.9 1.4 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DivIC PF04977.10 EPE29163.1 - 0.19 11.2 2.2 0.31 10.5 1.5 1.3 1 0 0 1 1 1 0 Septum formation initiator RBD-FIP PF09457.5 EPE29163.1 - 2.5 7.9 6.3 2.1 8.2 3.1 1.8 1 1 1 2 2 2 0 FIP domain Nsp1_C PF05064.8 EPE29164.1 - 1e-38 131.5 3.2 1e-38 131.5 2.2 1.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EPE29164.1 - 0.00042 20.5 45.5 0.00042 20.5 31.5 5.3 1 1 2 3 3 1 1 Nucleoporin FG repeat region WXG100 PF06013.7 EPE29164.1 - 0.031 14.2 0.5 0.031 14.2 0.3 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG AAA_13 PF13166.1 EPE29164.1 - 0.082 11.3 8.1 0.28 9.6 1.2 2.0 1 1 1 2 2 2 0 AAA domain APG6 PF04111.7 EPE29164.1 - 0.13 11.2 7.7 0.14 11.1 4.2 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EPE29164.1 - 0.58 10.5 1.7 7.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) MscS_porin PF12795.2 EPE29164.1 - 1.1 8.4 10.4 0.23 10.7 1.9 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Myosin_tail_1 PF01576.14 EPE29164.1 - 1.2 6.7 11.1 11 3.5 0.6 1.6 1 1 0 1 1 1 0 Myosin tail Laminin_II PF06009.7 EPE29164.1 - 1.4 8.7 8.3 2.2 8.0 0.6 2.6 2 1 0 2 2 2 0 Laminin Domain II Spc7 PF08317.6 EPE29164.1 - 3.4 6.2 10.2 1.9 7.0 0.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein V-SNARE PF05008.10 EPE29164.1 - 4.1 7.6 6.0 1.2 9.2 0.3 2.7 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF3450 PF11932.3 EPE29164.1 - 4.7 6.3 9.5 1.7 7.8 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin_2 PF14523.1 EPE29164.1 - 8.5 6.4 6.7 7.4 6.6 0.3 2.5 2 1 0 2 2 2 0 Syntaxin-like protein RRM_1 PF00076.17 EPE29166.1 - 6.3e-44 147.4 0.0 9.3e-17 60.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE29166.1 - 9.5e-25 86.3 0.0 2.3e-09 37.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE29166.1 - 3.5e-22 78.0 0.0 3e-08 33.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPE29166.1 - 2.7e-06 27.1 0.0 0.00011 21.9 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EPE29166.1 - 0.00014 21.5 0.0 0.0099 15.6 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif HAMP PF00672.20 EPE29167.1 - 1.6e-49 165.9 15.6 2.9e-11 43.3 0.2 7.1 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 EPE29167.1 - 8.4e-29 99.5 0.1 3.7e-28 97.4 0.0 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE29167.1 - 5.7e-26 90.7 1.5 6.6e-25 87.3 0.3 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EPE29167.1 - 3.9e-18 65.1 0.5 3.9e-18 65.1 0.4 4.0 5 0 0 5 5 5 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 EPE29167.1 - 0.0034 15.9 18.1 0.017 13.6 0.0 3.2 1 1 0 3 3 3 2 AAA domain DUF4279 PF14106.1 EPE29167.1 - 0.0059 16.4 0.0 12 5.7 0.0 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF4279) AAA_23 PF13476.1 EPE29167.1 - 0.25 11.6 3.7 0.92 9.7 2.6 2.0 1 0 0 1 1 1 0 AAA domain Tup_N PF08581.5 EPE29167.1 - 2.1 8.5 15.8 20 5.4 0.0 4.7 5 0 0 5 5 5 0 Tup N-terminal Pox_A_type_inc PF04508.7 EPE29167.1 - 2.4 8.1 5.2 5.4 7.0 0.0 4.1 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat DUF883 PF05957.8 EPE29167.1 - 3.5 8.0 20.7 1.7 9.0 0.1 5.9 3 1 2 6 6 6 0 Bacterial protein of unknown function (DUF883) NAAA-beta PF15508.1 EPE29167.1 - 4.2 7.8 10.0 51 4.3 0.0 6.3 7 2 1 8 8 8 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Membr_traf_MHD PF10540.4 EPE29168.1 - 1.5e-23 83.0 0.7 4e-23 81.7 0.2 2.0 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EPE29168.1 - 1.1e-16 60.4 0.0 3.3e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 EPE29168.1 - 3.1e-07 29.1 0.1 7.1e-07 27.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF810) Nucleoplasmin PF03066.10 EPE29169.1 - 0.17 11.3 7.3 0.35 10.3 5.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin zf-C2H2_4 PF13894.1 EPE29170.1 - 0.00054 20.1 4.0 0.13 12.6 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE29170.1 - 0.0093 16.2 6.4 0.35 11.3 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPE29170.1 - 0.62 10.0 3.3 13 5.8 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Sugar_tr PF00083.19 EPE29171.1 - 9.4e-39 133.2 14.1 2.3e-29 102.2 0.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPE29171.1 - 1.1e-07 30.9 31.7 1.1e-05 24.3 6.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily PCNA_N PF00705.13 EPE29172.1 - 4e-53 178.2 4.1 4e-53 178.2 2.8 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EPE29172.1 - 3.3e-49 166.0 0.1 1.6e-48 163.8 0.0 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EPE29172.1 - 2.1e-09 36.8 0.0 2.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EPE29172.1 - 0.00012 21.1 0.1 0.0017 17.3 0.0 2.1 2 0 0 2 2 2 1 Hus1-like protein DUF1480 PF07351.8 EPE29172.1 - 0.015 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) Phos_pyr_kin PF08543.7 EPE29173.1 - 1.4e-11 44.0 0.0 4.8e-11 42.3 0.0 1.8 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EPE29173.1 - 1.1e-09 37.9 0.2 2.3e-08 33.5 0.0 2.3 2 1 0 2 2 2 1 pfkB family carbohydrate kinase dUTPase PF00692.14 EPE29174.1 - 6.3e-45 151.7 0.0 9.1e-45 151.2 0.0 1.2 1 0 0 1 1 1 1 dUTPase TUSC2 PF15000.1 EPE29176.1 - 0.021 14.8 0.3 0.04 13.9 0.2 1.4 1 0 0 1 1 1 0 Tumour suppressor candidate 2 Abhydrolase_6 PF12697.2 EPE29178.1 - 1.8e-25 90.1 0.3 2.6e-25 89.6 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE29178.1 - 7.1e-13 48.5 0.0 3.5e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE29178.1 - 3e-11 43.3 0.2 4.1e-09 36.3 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EPE29178.1 - 3.9e-05 23.4 0.0 8.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EPE29178.1 - 0.0001 21.6 0.0 0.26 10.5 0.0 2.7 2 1 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.8 EPE29178.1 - 0.077 12.4 0.8 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) zf-C2H2 PF00096.21 EPE29179.1 - 2.9e-06 27.2 23.8 0.00036 20.6 0.5 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE29179.1 - 0.0097 16.1 25.2 0.019 15.2 0.6 5.1 4 0 0 4 4 4 2 C2H2-type zinc finger DUF202 PF02656.10 EPE29180.1 - 0.054 13.7 5.9 0.21 11.8 4.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) RseC_MucC PF04246.7 EPE29180.1 - 0.09 12.3 0.1 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Zn_clus PF00172.13 EPE29181.1 - 2.3e-07 30.6 8.8 3.5e-07 29.9 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sod_Cu PF00080.15 EPE29183.1 - 6.8e-11 42.5 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF4190 PF13828.1 EPE29184.1 - 0.097 12.2 1.4 0.18 11.3 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) Myb_DNA-bind_6 PF13921.1 EPE29185.1 - 5.5e-05 23.1 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPE29185.1 - 0.013 15.5 0.4 0.042 13.8 0.3 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rotamase_3 PF13616.1 EPE29185.1 - 0.08 13.2 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain Methyltransf_11 PF08241.7 EPE29186.1 - 1.2e-10 41.7 0.2 3.6e-10 40.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE29186.1 - 8.7e-08 32.7 0.0 2.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE29186.1 - 1.1e-07 31.5 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE29186.1 - 1e-06 29.1 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE29186.1 - 3.3e-06 26.9 0.0 4.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE29186.1 - 9.9e-06 24.8 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPE29186.1 - 1.3e-05 25.4 0.0 4.1e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE29186.1 - 0.0032 17.5 0.3 0.024 14.6 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPE29186.1 - 0.0088 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.7 EPE29186.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase APH PF01636.18 EPE29187.1 - 3.5e-16 59.6 0.0 6.4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE29187.1 - 3.8e-06 26.6 0.0 6.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPE29187.1 - 0.055 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase FYVE PF01363.16 EPE29189.1 - 0.0067 16.3 1.2 0.014 15.3 0.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-B_box PF00643.19 EPE29189.1 - 0.014 15.2 6.6 0.029 14.2 4.6 1.4 1 0 0 1 1 1 0 B-box zinc finger IBR PF01485.16 EPE29189.1 - 0.022 14.6 2.9 0.045 13.6 2.0 1.4 1 0 0 1 1 1 0 IBR domain C1_4 PF07975.7 EPE29189.1 - 0.5 10.4 6.0 1.2 9.2 4.2 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain C1_3 PF07649.7 EPE29189.1 - 2.3 8.3 5.4 3.5 7.7 3.7 1.3 1 0 0 1 1 1 0 C1-like domain SAGA-Tad1 PF12767.2 EPE29190.1 - 0.12 11.9 3.4 0.11 12.1 0.3 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit CpeS PF09367.5 EPE29193.1 - 0.035 14.0 0.1 0.04 13.8 0.1 1.1 1 0 0 1 1 1 0 CpeS-like protein Lactamase_B_3 PF13483.1 EPE29195.1 - 1.3e-08 34.7 0.0 2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain OB_NTP_bind PF07717.11 EPE29196.1 - 3.1e-25 88.2 0.0 3.1e-24 85.0 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPE29196.1 - 9.5e-25 86.5 0.1 4e-24 84.5 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPE29196.1 - 1.2e-12 47.5 0.0 3.8e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPE29196.1 - 2.1e-08 33.8 0.1 4.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPE29196.1 - 0.00035 20.4 0.2 0.21 11.4 0.0 2.6 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EPE29196.1 - 0.00053 19.0 0.0 0.00097 18.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EPE29196.1 - 0.00061 19.9 0.5 0.0023 18.1 0.1 2.1 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EPE29196.1 - 0.0022 16.9 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EPE29196.1 - 0.013 15.3 0.4 0.1 12.5 0.3 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EPE29196.1 - 0.015 14.7 0.4 0.042 13.2 0.3 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain KaiC PF06745.8 EPE29196.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EPE29196.1 - 0.031 13.9 0.1 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Flavi_DEAD PF07652.9 EPE29196.1 - 0.037 13.7 0.1 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Phage_G PF02306.10 EPE29196.1 - 0.058 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Major spike protein (G protein) GAD PF02938.9 EPE29196.1 - 0.069 13.3 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 GAD domain ABC_tran PF00005.22 EPE29196.1 - 0.076 13.3 0.1 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 EPE29196.1 - 0.37 11.0 0.0 0.37 11.0 0.0 2.3 1 1 1 2 2 1 0 AAA domain WD40 PF00400.27 EPE29197.1 - 6.8e-25 85.9 11.7 3e-07 30.0 0.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EPE29197.1 - 0.00038 18.7 2.4 0.00092 17.4 0.7 2.2 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Baculo_LEF-3 PF05847.6 EPE29197.1 - 0.021 13.7 1.3 0.035 12.9 0.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) Cyclin_N PF00134.18 EPE29197.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain Hep_59 PF07052.6 EPE29199.1 - 5.6e-15 55.5 0.2 6.7e-14 52.1 0.0 2.6 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 ResIII PF04851.10 EPE29200.1 - 3.8e-21 75.7 0.0 9.6e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPE29200.1 - 2.1e-20 72.8 0.0 3.5e-19 68.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE29200.1 - 1.1e-19 70.0 0.6 2.6e-19 68.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 EPE29200.1 - 0.017 14.0 0.0 0.053 12.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EPE29200.1 - 0.021 14.9 0.0 0.29 11.2 0.0 2.6 1 1 1 2 2 2 0 AAA domain TT_ORF2 PF02957.10 EPE29200.1 - 1.4 9.6 6.5 6.7 7.4 0.0 3.7 3 0 0 3 3 3 0 TT viral ORF2 DUF846 PF05832.7 EPE29201.1 - 8.4e-34 116.3 5.0 3.6e-32 111.0 3.4 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) AMP-binding PF00501.23 EPE29202.1 - 1.1e-72 244.6 0.0 1.3e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE29202.1 - 5.8e-11 43.1 0.0 1.5e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IMP_cyclohyd PF07826.6 EPE29203.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein F-box PF00646.28 EPE29204.1 - 8.7e-08 31.6 1.3 1.5e-07 30.8 0.9 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE29204.1 - 2.1e-07 30.5 1.0 4.3e-07 29.5 0.7 1.6 1 0 0 1 1 1 1 F-box-like Aldedh PF00171.17 EPE29205.1 - 1e-133 446.0 0.5 1.2e-133 445.8 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPE29205.1 - 0.05 12.3 0.0 0.092 11.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Sec20 PF03908.8 EPE29207.1 - 1.1e-18 66.6 0.4 3e-18 65.2 0.3 1.8 1 0 0 1 1 1 1 Sec20 TMF_TATA_bd PF12325.3 EPE29207.1 - 0.036 13.7 0.1 0.036 13.7 0.1 4.0 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding MRP_L53 PF10780.4 EPE29208.1 - 6.1e-17 61.3 1.6 1e-16 60.5 1.1 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.14 EPE29209.1 - 1.6e-52 177.1 0.1 2e-52 176.7 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.12 EPE29210.1 - 6.5e-44 150.0 0.1 1.5e-43 148.7 0.1 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Ctr PF04145.10 EPE29211.1 - 7.5e-40 136.2 1.2 9.1e-40 136.0 0.9 1.1 1 0 0 1 1 1 1 Ctr copper transporter family ATP_synt_I PF03899.10 EPE29211.1 - 0.014 15.5 4.8 0.96 9.6 0.1 2.1 2 0 0 2 2 2 0 ATP synthase I chain DUF3169 PF11368.3 EPE29211.1 - 0.024 13.8 2.2 0.41 9.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) AAA PF00004.24 EPE29212.1 - 2.2e-16 60.2 0.0 5.7e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EPE29212.1 - 2.5e-14 53.2 0.2 2.7e-13 49.8 0.0 2.4 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EPE29212.1 - 8e-13 48.1 0.0 1.8e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EPE29212.1 - 2.1e-11 43.1 0.1 3.9e-08 32.4 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EPE29212.1 - 2.9e-07 30.6 0.0 3.1e-06 27.3 0.0 2.5 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPE29212.1 - 2.1e-06 26.9 0.1 1.3e-05 24.3 0.0 2.3 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 EPE29212.1 - 4.8e-06 26.2 0.0 1.8e-05 24.3 0.0 1.9 2 0 0 2 2 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 EPE29212.1 - 1.9e-05 24.3 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE29212.1 - 2.6e-05 23.9 0.0 7.2e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EPE29212.1 - 4.3e-05 23.5 0.0 0.00056 19.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EPE29212.1 - 9.5e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EPE29212.1 - 0.00052 19.1 0.0 0.00086 18.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 EPE29212.1 - 0.00072 18.7 0.0 0.029 13.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EPE29212.1 - 0.00082 20.1 0.0 0.0025 18.6 0.0 1.8 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 EPE29212.1 - 0.00083 18.3 0.0 0.0026 16.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EPE29212.1 - 0.0014 18.3 0.1 0.014 15.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EPE29212.1 - 0.002 17.5 0.0 0.0091 15.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EPE29212.1 - 0.0023 17.5 1.7 0.0044 16.6 0.1 2.2 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.8 EPE29212.1 - 0.0044 15.7 0.1 0.35 9.5 0.0 2.5 3 0 0 3 3 3 1 TIP49 C-terminus AAA_18 PF13238.1 EPE29212.1 - 0.0056 16.9 0.0 0.015 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPE29212.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EPE29212.1 - 0.02 14.4 0.0 0.086 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EPE29212.1 - 0.022 14.2 0.0 0.067 12.6 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EPE29212.1 - 0.041 13.5 0.0 0.14 11.8 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EPE29212.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 EPE29212.1 - 0.051 13.0 0.0 0.62 9.4 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EPE29212.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPE29212.1 - 0.066 13.3 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 RNA helicase ResIII PF04851.10 EPE29212.1 - 0.068 12.9 0.0 0.21 11.3 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_3 PF07726.6 EPE29212.1 - 0.083 12.4 0.0 0.45 10.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 EPE29212.1 - 0.13 11.0 0.0 2 7.1 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain Pkinase PF00069.20 EPE29213.1 - 5.1e-30 104.4 0.0 2.1e-28 99.2 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29213.1 - 0.00011 21.3 0.0 0.0035 16.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2417 PF10329.4 EPE29214.1 - 1.5e-86 289.5 1.1 2.2e-86 289.0 0.7 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EPE29214.1 - 1e-06 28.8 0.1 2.2e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family ABC2_membrane_3 PF12698.2 EPE29214.1 - 0.025 13.6 11.2 0.044 12.8 7.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3165 PF11364.3 EPE29214.1 - 1.5 8.9 10.5 0.5 10.5 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) DUF4267 PF14087.1 EPE29214.1 - 9.9 5.7 9.2 0.6 9.7 2.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) Abhydrolase_6 PF12697.2 EPE29215.1 - 1.5e-21 77.3 0.1 2.7e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE29215.1 - 5.7e-09 35.8 0.0 1.3e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE29215.1 - 1.6e-05 24.5 0.0 0.00026 20.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EPE29215.1 - 0.00017 21.9 0.0 0.00045 20.5 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain DUF1746 PF08508.5 EPE29216.1 - 3.3e-41 139.8 1.2 4.5e-41 139.4 0.8 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RTC PF01137.16 EPE29217.1 - 8.6e-31 106.4 0.1 1.2e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EPE29217.1 - 7.5e-29 99.7 0.2 1.4e-28 98.9 0.2 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PWWP PF00855.12 EPE29218.1 - 6.7e-11 42.2 1.9 5.7e-10 39.2 1.1 2.6 1 1 0 1 1 1 1 PWWP domain Sec63 PF02889.11 EPE29219.1 - 5.5e-197 653.2 0.1 2.2e-108 362.2 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EPE29219.1 - 2.7e-52 176.6 0.0 4e-30 104.5 0.0 3.8 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EPE29219.1 - 2e-17 63.6 0.0 1.6e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPE29219.1 - 1.4e-10 40.8 0.0 1.6e-09 37.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPE29219.1 - 1.8e-10 41.0 0.2 0.00052 20.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 EPE29219.1 - 5.8e-05 22.1 0.0 0.25 10.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 EPE29219.1 - 0.00059 19.3 0.1 5 6.4 0.0 4.9 4 1 1 5 5 5 1 AAA-like domain PhoH PF02562.11 EPE29219.1 - 0.00081 18.6 0.0 0.027 13.7 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EPE29219.1 - 0.0076 15.9 0.0 0.28 10.9 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain DUF1548 PF07579.6 EPE29220.1 - 0.033 14.2 0.1 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) tRNA-synt_2d PF01409.15 EPE29221.1 - 2.2e-86 289.0 0.0 3e-86 288.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EPE29221.1 - 6.9e-06 25.0 0.2 0.00018 20.4 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EPE29221.1 - 0.0001 21.9 0.0 0.00026 20.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) CPSase_L_D2 PF02786.12 EPE29222.1 - 2.1e-83 278.7 0.0 3.2e-83 278.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EPE29222.1 - 1.8e-41 140.7 0.0 4.4e-41 139.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EPE29222.1 - 6.5e-16 58.4 0.0 1.5e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EPE29222.1 - 5.3e-13 49.0 0.0 9.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPE29222.1 - 2.7e-12 46.0 0.0 1.7e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EPE29222.1 - 1.3e-08 34.4 0.0 2.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EPE29222.1 - 5.7e-06 25.8 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.1 EPE29222.1 - 0.019 14.1 0.0 0.053 12.7 0.0 1.8 1 1 1 2 2 2 0 ATP-grasp domain HTH_AsnC-type PF13404.1 EPE29222.1 - 0.02 14.4 0.0 0.052 13.0 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain CPSase_L_D2 PF02786.12 EPE29223.1 - 2.7e-24 85.6 0.0 5.2e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 EPE29223.1 - 1.3e-20 73.9 0.2 5e-20 71.9 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPE29223.1 - 7.4e-11 41.3 0.0 2.7e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_chain PF00289.17 EPE29223.1 - 8e-10 38.8 0.7 2.9e-09 37.0 0.0 2.3 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp PF02222.17 EPE29223.1 - 2.5e-09 36.7 0.0 9.4e-09 34.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EPE29223.1 - 4.8e-09 35.9 0.1 9.8e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EPE29223.1 - 2.6e-06 27.0 0.0 4.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EPE29223.1 - 0.012 15.2 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MGS PF02142.17 EPE29223.1 - 0.074 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 MGS-like domain EAP30 PF04157.11 EPE29223.1 - 0.088 11.9 0.0 0.54 9.3 0.0 2.1 2 0 0 2 2 2 0 EAP30/Vps36 family NPL4 PF05021.10 EPE29224.1 - 7.2e-126 419.4 0.0 9.1e-126 419.1 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EPE29224.1 - 9e-69 229.8 0.1 1.5e-68 229.0 0.1 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EPE29224.1 - 0.00011 22.3 0.0 0.00028 21.1 0.0 1.7 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.4 EPE29225.1 - 2.2e-80 268.5 0.0 2.6e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 ORC3_N PF07034.6 EPE29227.1 - 1.1e-39 136.3 3.1 3.7e-25 88.5 1.8 2.4 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus PPR_2 PF13041.1 EPE29228.1 - 8.5e-10 38.4 0.6 0.089 12.7 0.0 7.6 8 0 0 8 8 8 2 PPR repeat family PPR_3 PF13812.1 EPE29228.1 - 6.1e-05 22.9 3.6 16 6.0 0.0 7.3 8 0 0 8 8 8 1 Pentatricopeptide repeat domain PPR PF01535.15 EPE29228.1 - 0.0071 16.2 8.9 3.6 7.7 0.1 6.1 6 0 0 6 6 6 1 PPR repeat DUF4346 PF14251.1 EPE29228.1 - 0.069 12.8 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) PPR_1 PF12854.2 EPE29228.1 - 0.32 10.5 3.2 24 4.5 0.0 4.0 4 0 0 4 4 4 0 PPR repeat DUF4187 PF13821.1 EPE29229.1 - 8.7e-19 66.8 1.2 2.8e-18 65.2 0.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EPE29229.1 - 1.1e-05 25.0 13.4 9e-05 22.1 9.3 2.3 1 1 0 1 1 1 1 G-patch domain CAP_GLY PF01302.20 EPE29230.1 - 1.2e-17 63.4 0.6 1.2e-17 63.4 0.4 1.9 2 0 0 2 2 2 1 CAP-Gly domain NPV_P10 PF05531.7 EPE29230.1 - 0.00012 22.2 2.1 0.069 13.3 0.6 2.8 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF812 PF05667.6 EPE29230.1 - 0.00017 20.2 6.3 0.00017 20.2 4.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF812) ApoLp-III PF07464.6 EPE29230.1 - 0.031 14.3 1.9 0.058 13.4 0.2 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SPOUT_MTase_2 PF14419.1 EPE29230.1 - 0.14 11.3 0.6 0.31 10.2 0.0 1.7 2 0 0 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP ISG65-75 PF11727.3 EPE29230.1 - 0.23 10.5 7.7 1.6 7.7 1.6 2.5 1 1 1 2 2 2 0 Invariant surface glycoprotein Baculo_PEP_C PF04513.7 EPE29230.1 - 0.27 11.0 1.0 7.1 6.4 0.4 2.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mod_r PF07200.8 EPE29230.1 - 0.29 11.0 11.8 0.21 11.4 1.5 3.2 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Phage_GP20 PF06810.6 EPE29230.1 - 0.39 10.1 12.4 1.2 8.5 0.1 3.7 4 0 0 4 4 4 0 Phage minor structural protein GP20 Spc7 PF08317.6 EPE29230.1 - 0.4 9.2 18.2 0.4 9.3 3.8 3.1 3 0 0 3 3 3 0 Spc7 kinetochore protein AAA_13 PF13166.1 EPE29230.1 - 0.41 9.0 11.2 0.18 10.2 2.3 2.0 1 1 1 2 2 2 0 AAA domain Med4 PF10018.4 EPE29230.1 - 1.1 8.6 14.4 0.11 11.8 0.3 3.2 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Lectin_N PF03954.9 EPE29230.1 - 1.9 7.8 4.4 2.3 7.5 0.1 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Cast PF10174.4 EPE29230.1 - 6.3 4.7 36.5 0.27 9.2 15.1 3.0 1 1 1 3 3 3 0 RIM-binding protein of the cytomatrix active zone PITH PF06201.8 EPE29231.1 - 5.8e-42 143.0 0.0 8.5e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EPE29231.1 - 6.3e-17 61.1 0.0 1.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EPE29231.1 - 0.0035 17.4 0.0 0.0085 16.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EPE29231.1 - 0.067 13.3 0.1 0.31 11.2 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain PknH_C PF14032.1 EPE29232.1 - 0.03 13.8 1.0 0.031 13.8 0.7 1.1 1 0 0 1 1 1 0 PknH-like extracellular domain MGC-24 PF05283.6 EPE29232.1 - 0.75 9.5 9.1 0.89 9.3 6.3 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Pkinase PF00069.20 EPE29233.1 - 3e-07 29.8 0.1 2.8e-06 26.6 0.1 2.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29233.1 - 0.0003 19.9 0.0 0.016 14.2 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EPE29233.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BESS PF02944.15 EPE29233.1 - 0.13 11.7 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 BESS motif AICARFT_IMPCHas PF01808.13 EPE29234.1 - 2.5e-109 365.1 0.0 3.3e-109 364.7 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EPE29234.1 - 1.3e-23 82.7 0.1 2.4e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DUF4401 PF14351.1 EPE29236.1 - 0.007 15.4 2.2 0.013 14.4 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) BCD PF15461.1 EPE29236.1 - 0.073 12.4 3.5 0.024 14.0 0.7 1.4 2 0 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase DUF202 PF02656.10 EPE29236.1 - 0.11 12.7 6.7 1.7 8.9 0.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF202) DUF4131 PF13567.1 EPE29236.1 - 1.1 8.6 4.1 3 7.2 2.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) MPC PF03650.8 EPE29237.1 - 4.1e-35 120.3 0.0 4.9e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) EutH PF04346.7 EPE29237.1 - 0.039 12.8 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH LSM PF01423.17 EPE29238.1 - 6.8e-17 60.7 0.0 9.1e-17 60.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 EPE29238.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Ribosomal_L5_C PF00673.16 EPE29239.1 - 1.6e-22 79.0 0.0 2.4e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EPE29239.1 - 2.9e-21 74.9 0.1 8.1e-21 73.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 DUF605 PF04652.11 EPE29240.1 - 7.9 5.7 12.3 9 5.5 8.5 1.1 1 0 0 1 1 1 0 Vta1 like CPSase_L_D2 PF02786.12 EPE29242.1 - 4.2e-80 267.9 0.1 6.8e-80 267.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EPE29242.1 - 1.9e-65 219.9 0.0 3.2e-65 219.2 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EPE29242.1 - 2.7e-36 124.0 0.0 5.9e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EPE29242.1 - 2.5e-31 107.8 0.0 7.3e-31 106.3 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EPE29242.1 - 3.7e-27 95.5 0.0 8.4e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EPE29242.1 - 3.5e-19 69.2 0.1 7.8e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EPE29242.1 - 3.2e-18 65.1 6.0 5.2e-18 64.4 2.9 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EPE29242.1 - 1.6e-16 60.0 0.0 7.2e-16 57.8 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EPE29242.1 - 1.7e-10 40.6 0.0 3.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EPE29242.1 - 4.1e-10 39.1 4.4 2.9e-07 30.0 0.1 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like RimK PF08443.6 EPE29242.1 - 4.8e-08 32.6 0.0 1.1e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EPE29242.1 - 5.7e-07 29.0 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EPE29242.1 - 4.8e-05 23.2 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EPE29242.1 - 0.00023 21.4 0.4 0.019 15.3 0.2 3.3 2 1 1 3 3 3 1 HlyD family secretion protein HlyD_2 PF12700.2 EPE29242.1 - 0.00028 20.1 0.1 0.17 11.0 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 EPE29242.1 - 0.0011 18.2 0.3 0.016 14.5 0.1 2.4 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 EPE29242.1 - 0.037 13.5 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.4 EPE29242.1 - 0.071 12.8 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.1 EPE29242.1 - 0.088 12.5 2.4 0.65 9.7 1.7 2.2 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Clathrin PF00637.15 EPE29243.1 - 4e-212 694.3 33.4 5e-35 120.1 2.8 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EPE29243.1 - 7.1e-32 109.1 1.1 1.9e-31 107.7 0.1 2.4 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 EPE29243.1 - 2e-25 87.2 1.1 0.00041 20.4 0.0 7.8 7 0 0 7 7 7 5 Clathrin propeller repeat TPR_12 PF13424.1 EPE29243.1 - 0.00017 21.4 0.4 1.4 8.8 0.0 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE29243.1 - 0.00029 20.4 5.0 8.4 6.4 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat Clathrin-link PF09268.5 EPE29243.1 - 0.00044 19.2 0.7 0.0012 17.7 0.2 2.1 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Vps39_1 PF10366.4 EPE29243.1 - 0.00068 19.6 3.3 2.2 8.3 0.0 5.4 5 1 1 6 6 6 1 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.23 EPE29243.1 - 0.019 14.5 1.6 5.7 6.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPE29243.1 - 0.035 14.4 4.3 43 4.5 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPE29243.1 - 0.28 11.1 8.4 5.7 7.1 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPE29243.1 - 3.1 8.6 16.1 68 4.5 0.0 8.9 12 0 0 12 12 11 0 Tetratricopeptide repeat DUF1640 PF07798.6 EPE29244.1 - 1.3e-63 214.2 10.2 1.6e-63 213.9 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) cwf21 PF08312.7 EPE29244.1 - 0.71 9.7 5.4 5.3 6.9 3.7 2.5 1 1 0 1 1 1 0 cwf21 domain FTA4 PF13093.1 EPE29244.1 - 1.4 8.2 9.6 11 5.3 6.6 2.0 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GTP_EFTU PF00009.22 EPE29245.1 - 5.8e-39 133.4 0.0 9.4e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EPE29245.1 - 2e-36 123.8 0.4 4.8e-36 122.6 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EPE29245.1 - 2.6e-10 40.2 0.6 5.6e-10 39.1 0.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPE29245.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MFS_1 PF07690.11 EPE29247.1 - 1.4e-42 145.7 53.6 1.4e-42 145.7 37.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE29247.1 - 1.2e-07 30.3 29.9 1.6e-07 29.9 20.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WTF PF03303.8 EPE29247.1 - 0.41 10.0 3.9 0.93 8.8 2.7 1.6 1 0 0 1 1 1 0 WTF protein CUE PF02845.11 EPE29248.1 - 2.3e-08 33.3 1.6 0.00015 21.2 0.1 2.5 2 0 0 2 2 2 2 CUE domain UBA PF00627.26 EPE29248.1 - 4.1e-08 32.8 1.7 8.2e-05 22.3 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain DMA PF03474.9 EPE29248.1 - 0.00018 21.2 0.3 0.15 11.8 0.0 2.6 2 0 0 2 2 2 2 DMRTA motif UBA_4 PF14555.1 EPE29248.1 - 0.29 10.6 2.2 4.8 6.7 0.1 2.4 2 0 0 2 2 2 0 UBA-like domain Pkinase PF00069.20 EPE29249.1 - 5.2e-69 232.2 0.0 7.7e-69 231.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29249.1 - 4.1e-50 170.2 0.0 6.3e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE29249.1 - 0.00031 19.8 0.0 0.015 14.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Thioredoxin_7 PF13899.1 EPE29250.1 - 1.9e-14 53.4 0.1 4.3e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EPE29250.1 - 5.8e-11 41.7 0.0 2e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.15 EPE29250.1 - 1e-05 25.5 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 EPE29250.1 - 0.0017 18.0 0.1 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 EPE29250.1 - 0.0058 16.8 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Ecm29 PF13001.2 EPE29251.1 - 1.2e-135 452.9 1.0 1.6e-135 452.4 0.1 1.7 2 0 0 2 2 2 1 Proteasome stabiliser HEAT_2 PF13646.1 EPE29251.1 - 0.00057 20.1 15.4 0.066 13.4 0.0 7.9 9 2 1 10 10 10 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EPE29251.1 - 0.004 17.4 0.9 0.28 11.6 0.0 3.8 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EPE29251.1 - 0.0062 16.9 15.1 26 5.4 0.0 9.8 9 1 2 11 11 11 1 HEAT-like repeat HEAT PF02985.17 EPE29251.1 - 0.0072 16.3 11.0 22 5.4 0.1 8.5 10 0 0 10 10 10 1 HEAT repeat PCI PF01399.22 EPE29252.1 - 2.5e-17 63.1 0.7 9.7e-17 61.2 0.5 2.1 1 0 0 1 1 1 1 PCI domain DUF2223 PF09985.4 EPE29252.1 - 0.11 11.7 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2223) ADK PF00406.17 EPE29253.1 - 9.1e-48 161.9 0.1 1.2e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EPE29253.1 - 1e-08 35.5 0.0 1.5e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPE29253.1 - 2.3e-06 27.5 0.0 1.3e-05 25.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EPE29253.1 - 2.6e-06 28.2 0.0 4.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EPE29253.1 - 8.1e-05 22.0 0.8 0.019 14.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase EthD PF07110.6 EPE29254.1 - 1.9e-22 80.0 0.3 2.4e-22 79.6 0.2 1.2 1 0 0 1 1 1 1 EthD domain Acetyltransf_2 PF00797.12 EPE29255.1 - 4.2e-47 160.7 0.1 5.4e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Peptidase_M20 PF01546.23 EPE29256.1 - 6.7e-26 90.9 0.0 9.9e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPE29256.1 - 1.1e-06 28.3 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EPE29256.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 FAD_binding_3 PF01494.14 EPE29258.1 - 2.6e-63 214.2 0.0 3.8e-63 213.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amidohydro_4 PF13147.1 EPE29258.1 - 1.6e-22 80.8 0.0 2.8e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EPE29258.1 - 1.8e-09 37.7 0.0 1.2e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EPE29258.1 - 3.4e-09 36.3 0.1 3.4e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase Phe_hydrox_dim PF07976.7 EPE29258.1 - 6.7e-06 25.8 0.0 1.6e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Amidohydro_3 PF07969.6 EPE29258.1 - 0.0019 17.5 0.0 0.1 11.7 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family DAO PF01266.19 EPE29258.1 - 0.0078 15.1 0.0 0.02 13.8 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPE29258.1 - 0.11 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiS PF02597.15 EPE29259.1 - 1.2e-09 38.5 0.0 1.5e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 ThiS family RNB PF00773.14 EPE29260.1 - 2.8e-52 178.0 0.0 1.3e-50 172.5 0.0 2.1 2 0 0 2 2 2 2 RNB domain S1 PF00575.18 EPE29260.1 - 0.14 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 S1 RNA binding domain PAP1 PF08601.5 EPE29261.1 - 1.5 8.4 6.4 1.8 8.1 4.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Pkinase PF00069.20 EPE29262.1 - 2.1e-27 95.9 0.0 3.6e-27 95.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29262.1 - 7e-07 28.5 0.1 0.0018 17.3 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase WD40 PF00400.27 EPE29263.1 - 5e-07 29.3 0.0 7.9e-06 25.5 0.1 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EPE29263.1 - 0.0005 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term DUF2415 PF10313.4 EPE29263.1 - 0.077 12.6 0.1 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) DLH PF01738.13 EPE29266.1 - 4e-33 114.5 0.0 4.8e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPE29266.1 - 1.8e-07 30.9 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2752 PF10825.3 EPE29266.1 - 0.091 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) MOSC_N PF03476.11 EPE29267.1 - 2.5e-24 85.2 0.0 6e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.14 EPE29267.1 - 1.9e-21 76.2 0.0 3.1e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.12 EPE29267.1 - 2.2e-20 72.5 0.0 5e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Sod_Fe_C PF02777.13 EPE29268.1 - 1.3e-09 37.8 0.0 0.00047 19.9 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EPE29268.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain SAM_2 PF07647.12 EPE29269.1 - 2.9e-09 36.6 0.0 5.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EPE29269.1 - 7.9e-09 35.5 0.0 1.8e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EPE29269.1 - 6.4e-06 26.3 0.0 2e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 PH domain Fungal_trans_2 PF11951.3 EPE29271.1 - 8.6e-83 278.0 0.1 1.1e-82 277.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE29271.1 - 1.5e-07 31.2 7.4 2.5e-07 30.4 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2235 PF09994.4 EPE29272.1 - 6.6e-64 215.9 0.0 1e-63 215.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SHR3_chaperone PF08229.6 EPE29273.1 - 7.6e-77 256.7 0.0 8.6e-77 256.5 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DcuC PF03606.10 EPE29273.1 - 0.016 13.4 0.2 3.1 5.9 0.0 2.0 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier Sugar_tr PF00083.19 EPE29274.1 - 1.5e-77 261.1 22.3 1.8e-77 260.8 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE29274.1 - 1.1e-21 77.0 26.8 1.1e-21 77.0 18.6 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 EPE29277.1 - 4.5e-17 62.5 0.0 9.9e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Yip1 PF04893.12 EPE29278.1 - 0.005 16.3 0.6 0.005 16.3 0.4 1.6 2 0 0 2 2 2 1 Yip1 domain S1FA PF04689.8 EPE29278.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA Cu_bind_like PF02298.12 EPE29278.1 - 0.16 11.7 0.0 1.2 8.9 0.0 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain Amnionless PF14828.1 EPE29278.1 - 0.18 10.2 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless FimP PF09766.4 EPE29279.1 - 8.5e-27 94.1 8.4 1.1e-26 93.7 5.8 1.1 1 0 0 1 1 1 1 Fms-interacting protein YfiO PF13525.1 EPE29279.1 - 0.019 14.4 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein LAG1-DNAbind PF09271.6 EPE29279.1 - 0.15 12.5 1.4 15 6.0 0.1 2.1 1 1 0 2 2 2 0 LAG1, DNA binding K-box PF01486.12 EPE29279.1 - 0.18 11.5 9.0 0.11 12.3 3.5 2.6 1 1 1 2 2 2 0 K-box region DUF4200 PF13863.1 EPE29279.1 - 0.24 11.3 10.8 0.49 10.3 1.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF948 PF06103.6 EPE29279.1 - 0.52 10.1 3.6 7.1 6.5 0.2 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Pinin_SDK_memA PF04696.8 EPE29279.1 - 3.7 7.1 7.9 8.5 5.9 1.1 2.4 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF3074 PF11274.3 EPE29280.1 - 1.3e-40 139.0 0.5 1.6e-40 138.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) DMRL_synthase PF00885.14 EPE29281.1 - 2.1e-43 147.4 0.0 2.4e-25 88.9 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Cation_efflux PF01545.16 EPE29283.1 - 1.9e-30 105.9 10.1 2.6e-30 105.4 7.0 1.1 1 0 0 1 1 1 1 Cation efflux family Rad60-SLD PF11976.3 EPE29284.1 - 8.4e-16 57.4 2.9 9.7e-15 54.0 0.3 3.0 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like LSM PF01423.17 EPE29285.1 - 1.4e-20 72.6 0.2 1.6e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPE29285.1 - 0.00011 22.0 0.2 0.00013 21.7 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 EPE29285.1 - 0.024 14.4 0.1 0.029 14.1 0.1 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain UnbV_ASPIC PF07593.7 EPE29285.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 ASPIC and UnbV Methyltransf_11 PF08241.7 EPE29286.1 - 6.3e-13 49.0 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE29286.1 - 2.2e-06 28.0 0.0 3.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE29286.1 - 2.5e-06 28.0 0.0 4.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE29286.1 - 5.1e-06 26.2 0.0 8.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE29286.1 - 7.5e-05 22.3 0.0 0.00017 21.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE29286.1 - 8.1e-05 21.8 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EPE29286.1 - 0.0015 18.5 0.0 0.0076 16.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EPE29286.1 - 0.0074 16.2 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.10 EPE29286.1 - 0.022 14.4 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_25 PF13649.1 EPE29286.1 - 0.027 14.8 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PI3_PI4_kinase PF00454.22 EPE29287.1 - 2.6e-41 141.6 0.1 2.7e-40 138.2 0.0 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EPE29287.1 - 7.3e-26 90.4 0.1 2.2e-25 88.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Proteasome PF00227.21 EPE29288.1 - 1.2e-29 102.9 0.4 4e-29 101.2 0.2 1.8 2 1 0 2 2 2 1 Proteasome subunit EPSP_synthase PF00275.15 EPE29289.1 - 3.8e-128 427.4 0.0 6.1e-128 426.8 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EPE29289.1 - 5.6e-101 336.8 0.0 1.3e-100 335.6 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EPE29289.1 - 4.4e-64 216.2 0.0 7e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EPE29289.1 - 7.7e-34 116.8 0.0 4.6e-32 111.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EPE29289.1 - 8.5e-24 83.4 0.0 2.2e-23 82.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EPE29289.1 - 1.8e-12 47.5 0.0 5.5e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EPE29289.1 - 1.4e-07 31.1 0.0 3.6e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EPE29289.1 - 0.002 18.9 0.0 0.0077 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain bZIP_2 PF07716.10 EPE29290.1 - 0.011 15.5 8.1 0.011 15.5 5.6 1.7 2 0 0 2 2 2 0 Basic region leucine zipper Sporozoite_P67 PF05642.6 EPE29290.1 - 0.016 13.0 5.5 0.023 12.5 3.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CAF-1_p150 PF11600.3 EPE29290.1 - 0.052 12.9 13.4 0.094 12.0 9.3 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4653 PF15546.1 EPE29290.1 - 0.12 11.6 6.5 0.16 11.2 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) bZIP_1 PF00170.16 EPE29290.1 - 1.1 9.2 13.6 0.076 12.9 4.8 2.2 2 1 1 3 3 3 0 bZIP transcription factor Macoilin PF09726.4 EPE29290.1 - 5.7 5.0 10.4 7.4 4.7 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Period_C PF12114.3 EPE29290.1 - 7.7 6.0 18.0 3.7 7.0 0.6 2.3 2 0 0 2 2 2 0 Period protein 2/3C-terminal region GHMP_kinases_N PF00288.21 EPE29292.1 - 1.4e-20 73.1 0.0 4e-20 71.6 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPE29292.1 - 2.5e-11 43.5 0.1 5.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EPE29292.1 - 0.11 11.8 1.1 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Galactokinase galactose-binding signature PPTA PF01239.17 EPE29293.1 - 1.8e-38 128.2 10.6 1.4e-08 33.6 0.9 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF4458 PF14660.1 EPE29293.1 - 0.062 13.3 4.0 0.52 10.3 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4458) DUF4219 PF13961.1 EPE29293.1 - 2.5 7.6 7.3 13 5.2 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4219) Spherulin4 PF12138.3 EPE29295.1 - 7.1e-10 38.7 0.0 1.7e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Spherulation-specific family 4 Gram_pos_anchor PF00746.16 EPE29295.1 - 0.097 12.5 0.5 0.34 10.7 0.4 2.0 1 0 0 1 1 1 0 Gram positive anchor Lipase_GDSL_2 PF13472.1 EPE29296.1 - 9.6e-09 35.6 0.1 1.7e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE29296.1 - 1.4e-06 28.3 0.1 2.2e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aspzincin_M35 PF14521.1 EPE29296.1 - 2e-06 28.3 0.0 6.4e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF4344 PF14247.1 EPE29296.1 - 0.099 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) HSP70 PF00012.15 EPE29297.1 - 5.2e-99 331.8 0.1 1e-65 221.8 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein Beta-lactamase PF00144.19 EPE29298.1 - 2.4e-31 108.9 0.0 5.4e-31 107.8 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EPE29298.1 - 0.032 13.5 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase NAD_binding_10 PF13460.1 EPE29299.1 - 5.7e-12 46.0 0.2 9.4e-12 45.3 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE29299.1 - 7.3e-07 28.6 0.9 1e-06 28.2 0.6 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EPE29299.1 - 4.8e-06 26.1 0.1 7.3e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPE29299.1 - 0.0035 16.2 0.1 0.0059 15.5 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EPE29299.1 - 0.0085 15.0 0.3 0.013 14.4 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CbiJ PF02571.9 EPE29299.1 - 0.014 14.7 0.2 0.023 14.0 0.2 1.3 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK 3Beta_HSD PF01073.14 EPE29299.1 - 0.032 12.9 0.1 0.042 12.5 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPE29299.1 - 0.039 13.8 1.2 0.071 13.0 0.8 1.4 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.13 EPE29299.1 - 0.057 13.4 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 EPE29299.1 - 0.088 12.6 0.1 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Cytochrom_B561 PF03188.11 EPE29302.1 - 8.3e-19 67.7 3.7 1.4e-18 66.9 2.6 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4064 PF13273.1 EPE29302.1 - 0.011 15.7 1.6 0.011 15.7 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Cytochrom_B_N PF00033.14 EPE29302.1 - 0.48 9.7 6.9 0.065 12.5 1.3 2.1 1 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB PepSY_TM_3 PF13706.1 EPE29302.1 - 0.64 9.4 6.4 1 8.8 1.1 3.0 3 0 0 3 3 3 0 PepSY-associated TM helix DUF2231 PF09990.4 EPE29302.1 - 1.4 9.2 11.8 0.074 13.3 1.0 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) DUF1230 PF06799.6 EPE29302.1 - 1.7 8.5 4.4 7.1 6.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1230) COX15-CtaA PF02628.10 EPE29302.1 - 2.9 6.6 12.1 2.5 6.9 0.2 2.5 1 1 0 3 3 3 0 Cytochrome oxidase assembly protein Allantoicase PF03561.10 EPE29303.1 - 3.3e-105 348.0 0.0 7.9e-57 190.9 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.14 EPE29304.1 - 1.6e-18 66.5 2.5 1.9e-16 59.7 1.8 2.6 1 1 0 1 1 1 1 DIL domain Ank_2 PF12796.2 EPE29304.1 - 8.9e-16 58.0 0.1 2.5e-15 56.6 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE29304.1 - 3e-13 48.8 0.2 1.8e-05 24.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EPE29304.1 - 2.4e-10 40.3 0.0 2.9e-07 30.5 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE29304.1 - 1.6e-09 37.9 0.0 0.0016 18.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE29304.1 - 2.8e-06 27.0 0.1 0.14 12.4 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat RabGAP-TBC PF00566.13 EPE29306.1 - 3.8e-36 124.5 0.0 5.6e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_M13_N PF05649.8 EPE29307.1 - 1.8e-92 310.3 0.0 2.3e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EPE29307.1 - 8e-57 191.7 0.0 1.3e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 HATPase_c PF02518.21 EPE29308.1 - 3.2e-22 78.3 0.6 6.8e-22 77.2 0.4 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE29308.1 - 9.9e-22 77.0 0.2 4.1e-21 75.0 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EPE29308.1 - 3.2e-20 71.8 0.0 7.8e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EPE29308.1 - 1.1e-19 70.3 7.3 2.2e-10 40.4 1.8 3.8 4 0 0 4 4 4 3 PAS fold PAS_9 PF13426.1 EPE29308.1 - 2e-12 47.4 0.0 9.4e-06 25.9 0.0 3.5 2 1 0 2 2 2 2 PAS domain PAS PF00989.19 EPE29308.1 - 6.2e-10 38.8 0.0 5.4e-05 22.9 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.5 EPE29308.1 - 5.4e-09 36.0 0.4 5.9e-07 29.4 0.1 3.2 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 EPE29308.1 - 0.085 12.7 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 PAS domain Ank_2 PF12796.2 EPE29309.1 - 1.3e-25 89.5 0.0 1.3e-10 41.4 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPE29309.1 - 2e-16 58.8 0.9 0.00052 19.6 0.0 7.0 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 EPE29309.1 - 6.5e-16 57.9 0.1 0.0058 16.8 0.0 7.2 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE29309.1 - 1.9e-14 53.7 0.0 0.0007 20.0 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE29309.1 - 1.3e-11 43.5 0.7 0.0021 18.1 0.0 7.4 8 0 0 8 8 8 1 Ankyrin repeat U79_P34 PF03064.11 EPE29310.1 - 0.00064 19.3 10.6 0.00093 18.7 7.3 1.2 1 0 0 1 1 1 1 HSV U79 / HCMV P34 DUF1510 PF07423.6 EPE29310.1 - 0.02 14.2 8.9 0.036 13.4 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Peptidase_S49_N PF08496.5 EPE29310.1 - 0.086 12.6 7.0 0.22 11.3 4.8 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2201_N PF13203.1 EPE29310.1 - 0.77 8.8 6.8 1.3 8.1 4.7 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain SAPS PF04499.10 EPE29310.1 - 0.85 8.1 5.9 1.2 7.7 4.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Med19 PF10278.4 EPE29310.1 - 1.1 8.9 15.2 1.8 8.2 10.5 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Vfa1 PF08432.5 EPE29310.1 - 1.3 9.0 17.1 2.2 8.2 11.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Hid1 PF12722.2 EPE29310.1 - 2 5.9 4.8 2.6 5.6 3.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SHR3_chaperone PF08229.6 EPE29310.1 - 2.7 6.9 4.1 4.7 6.1 2.9 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 Bap31 PF05529.7 EPE29310.1 - 10 5.5 7.1 19 4.6 4.9 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like NAD_binding_11 PF14833.1 EPE29312.1 - 1.3e-43 147.9 0.6 1.4e-24 86.4 0.0 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EPE29312.1 - 3e-35 121.4 0.0 6.2e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EPE29312.1 - 3.4e-05 24.1 0.0 0.00013 22.3 0.0 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EPE29312.1 - 0.005 16.5 0.2 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EPE29312.1 - 0.018 14.4 0.0 0.045 13.1 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EPE29312.1 - 0.12 11.7 0.0 5.2 6.4 0.0 2.4 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RasGEF PF00617.14 EPE29313.1 - 9.1e-44 149.4 0.1 1.4e-43 148.8 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EPE29313.1 - 2.8e-14 53.0 0.4 6.2e-14 51.9 0.3 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Cir_N PF10197.4 EPE29315.1 - 0.051 13.6 0.1 0.051 13.6 0.1 4.2 3 1 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.24 EPE29316.1 - 1.4e-55 187.0 0.0 1.4e-38 132.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EPE29316.1 - 1e-11 44.6 0.0 5.7e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EPE29316.1 - 9e-11 41.2 0.6 1.1e-08 34.6 0.2 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EPE29316.1 - 3.4e-10 40.1 0.2 0.00083 19.4 0.0 3.9 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 EPE29316.1 - 8.7e-10 39.4 0.1 0.0015 19.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EPE29316.1 - 1.4e-09 37.1 0.1 0.00018 20.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EPE29316.1 - 2.2e-09 37.2 0.0 0.00019 21.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPE29316.1 - 1e-08 35.3 0.0 0.01 15.8 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.1 EPE29316.1 - 1.4e-08 35.0 0.1 0.004 17.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EPE29316.1 - 2.6e-08 33.5 0.7 0.0028 17.3 0.0 2.9 3 0 0 3 3 2 2 Part of AAA domain AAA_5 PF07728.9 EPE29316.1 - 3.5e-08 33.2 0.2 0.0022 17.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPE29316.1 - 3.7e-08 33.4 0.0 3.7e-05 23.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EPE29316.1 - 8.7e-08 31.4 0.2 0.0027 16.7 0.0 2.9 3 1 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EPE29316.1 - 1.9e-07 31.0 0.0 0.0086 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EPE29316.1 - 5.2e-07 29.0 0.1 0.0057 15.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EPE29316.1 - 3.4e-06 27.1 0.0 0.087 13.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EPE29316.1 - 8.5e-06 25.3 0.2 0.025 13.9 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EPE29316.1 - 9.6e-06 24.8 0.1 0.04 13.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin Sigma54_activat PF00158.21 EPE29316.1 - 3.6e-05 23.3 0.0 0.27 10.7 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain NB-ARC PF00931.17 EPE29316.1 - 5.8e-05 22.0 0.4 0.045 12.5 0.0 3.0 2 1 1 3 3 3 1 NB-ARC domain NACHT PF05729.7 EPE29316.1 - 0.00011 21.8 0.4 0.1 12.2 0.0 3.3 4 0 0 4 4 3 1 NACHT domain AAA_28 PF13521.1 EPE29316.1 - 0.00015 21.7 0.0 0.33 10.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 EPE29316.1 - 0.00017 21.9 0.2 0.03 14.6 0.1 2.5 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 EPE29316.1 - 0.00022 20.8 2.3 0.81 9.2 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EPE29316.1 - 0.00038 19.9 2.7 0.99 8.7 0.0 3.8 2 2 2 4 4 4 2 AAA domain KTI12 PF08433.5 EPE29316.1 - 0.00045 19.5 0.0 0.34 10.0 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 KaiC PF06745.8 EPE29316.1 - 0.00047 19.3 0.9 0.036 13.1 0.1 2.7 2 1 1 3 3 3 1 KaiC PhoH PF02562.11 EPE29316.1 - 0.0006 19.1 0.0 0.92 8.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.4 EPE29316.1 - 0.00065 18.7 0.1 0.62 8.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EPE29316.1 - 0.00084 18.9 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EPE29316.1 - 0.00085 19.3 0.1 1.8 8.5 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 EPE29316.1 - 0.0012 18.5 0.7 7.8 6.1 0.0 3.5 2 2 1 3 3 3 0 Archaeal ATPase AAA_3 PF07726.6 EPE29316.1 - 0.002 17.7 0.0 0.81 9.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EPE29316.1 - 0.0022 16.9 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EPE29316.1 - 0.0065 16.0 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EPE29316.1 - 0.0077 16.0 0.1 1.6 8.5 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EPE29316.1 - 0.0089 15.6 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EPE29316.1 - 0.009 15.5 0.1 1.9 7.9 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EPE29316.1 - 0.021 14.5 0.1 7.7 6.1 0.0 2.6 2 0 0 2 2 2 0 NTPase SRP54 PF00448.17 EPE29316.1 - 0.023 14.1 0.0 2.3 7.6 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EPE29316.1 - 0.041 13.3 0.0 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain CPT PF07931.7 EPE29316.1 - 0.063 12.9 0.1 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein cobW PF02492.14 EPE29316.1 - 0.071 12.5 0.2 6.3 6.2 0.0 2.7 2 1 1 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain IPT PF01745.11 EPE29316.1 - 0.074 12.2 0.0 0.72 8.9 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase Torsin PF06309.6 EPE29316.1 - 0.079 12.8 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Torsin DEAD PF00270.24 EPE29316.1 - 0.096 12.1 0.3 25 4.2 0.0 3.7 2 2 1 4 4 4 0 DEAD/DEAH box helicase SKI PF01202.17 EPE29316.1 - 0.11 12.3 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase APS_kinase PF01583.15 EPE29316.1 - 0.13 11.9 0.0 17 5.0 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Viral_helicase1 PF01443.13 EPE29316.1 - 0.19 11.2 0.0 2 7.8 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SurE PF01975.12 EPE29317.1 - 1.7e-37 128.6 0.0 2.4e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE DUF3328 PF11807.3 EPE29319.1 - 2.9e-29 102.3 0.3 3.7e-29 101.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Dyp_perox PF04261.7 EPE29320.1 - 1.6e-07 30.4 0.0 3.7e-06 25.9 0.0 2.8 4 0 0 4 4 4 1 Dyp-type peroxidase family TFIID-18kDa PF02269.11 EPE29320.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF1162 PF06650.7 EPE29321.1 - 4.1e-92 308.3 0.0 1.3e-89 300.0 0.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EPE29321.1 - 5.3e-43 145.3 0.1 1.8e-42 143.5 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EPE29321.1 - 5e-07 29.7 0.1 3.6e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 ATG C terminal domain TFIID_20kDa PF03847.8 EPE29323.1 - 2.8e-19 69.1 0.0 3.9e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EPE29323.1 - 0.0039 17.2 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.11 EPE29323.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit AhpC-TSA PF00578.16 EPE29324.1 - 2.9e-27 94.8 0.0 5.1e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPE29324.1 - 4.9e-15 55.3 0.0 7.4e-15 54.7 0.0 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EPE29324.1 - 0.022 14.7 0.0 0.12 12.2 0.0 1.9 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme GTP_EFTU PF00009.22 EPE29326.1 - 5.3e-47 159.6 0.0 8.6e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EPE29326.1 - 1.8e-37 127.5 5.1 3.1e-37 126.7 3.5 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EPE29326.1 - 7.8e-19 67.3 0.0 1.5e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.17 EPE29326.1 - 8.6e-06 25.2 0.0 2.4e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Ras family GTP_EFTU_D2 PF03144.20 EPE29326.1 - 1.5e-05 24.9 0.0 3.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPE29326.1 - 8e-05 22.5 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPE29326.1 - 0.0025 17.0 0.0 0.0055 15.9 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.1 EPE29326.1 - 0.0081 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II HORMA PF02301.13 EPE29327.1 - 2.5e-46 157.8 0.0 2.8e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 HORMA domain Alba PF01918.16 EPE29327.1 - 0.045 13.3 0.1 0.08 12.5 0.1 1.5 1 0 0 1 1 1 0 Alba Bap31 PF05529.7 EPE29328.1 - 2.4 7.5 0.0 2.4 7.5 0.0 3.1 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like SpoIIIAH PF12685.2 EPE29329.1 - 0.073 12.5 4.0 0.093 12.2 2.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Phage_stabilise PF11134.3 EPE29329.1 - 0.077 11.5 0.2 0.085 11.4 0.2 1.1 1 0 0 1 1 1 0 Phage stabilisation protein DUF883 PF05957.8 EPE29329.1 - 0.16 12.4 7.4 0.5 10.8 5.0 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.13 EPE29329.1 - 2.9 7.7 13.1 1.2 8.8 5.8 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4200 PF13863.1 EPE29329.1 - 4.2 7.3 7.9 3.8 7.4 4.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) MT0933_antitox PF14013.1 EPE29329.1 - 9 6.4 11.1 9.4 6.4 4.2 2.8 1 1 1 3 3 3 0 MT0933-like antitoxin protein YtxH PF12732.2 EPE29329.1 - 9.4 6.6 9.7 3.4e+02 1.6 6.8 2.4 1 1 0 1 1 1 0 YtxH-like protein His_Phos_1 PF00300.17 EPE29330.1 - 5.4e-16 59.0 0.2 1.6e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1761 PF08570.5 EPE29331.1 - 5.1e-25 87.9 1.4 5.7e-25 87.7 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) CD20 PF04103.10 EPE29331.1 - 0.091 12.6 0.7 0.15 11.9 0.5 1.4 1 0 0 1 1 1 0 CD20-like family Acetyltransf_1 PF00583.19 EPE29332.1 - 8.9e-15 54.4 0.1 2.6e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPE29332.1 - 7.7e-07 28.7 0.2 1.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPE29332.1 - 0.00092 19.3 0.0 0.0023 18.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPE29332.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPE29332.1 - 0.0049 16.8 0.0 0.008 16.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE29332.1 - 0.011 15.5 0.1 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPE29332.1 - 0.057 13.5 0.0 0.095 12.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EPE29332.1 - 0.09 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase adh_short PF00106.20 EPE29333.1 - 3.3e-32 111.7 0.0 4.1e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE29333.1 - 1.9e-24 86.7 0.0 6.3e-24 85.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE29333.1 - 2.6e-15 56.5 0.0 3.6e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE29333.1 - 0.00014 21.3 0.0 0.00048 19.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPE29333.1 - 0.027 14.2 0.5 0.051 13.3 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EPE29333.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) tRNA-synt_1g PF09334.6 EPE29334.1 - 1.4e-141 471.7 0.0 2.1e-141 471.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EPE29334.1 - 3.5e-08 31.9 0.4 0.0012 17.0 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Yae1_N PF09811.4 EPE29335.1 - 1.2e-06 27.8 5.8 2.3e-06 27.0 4.0 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF1024 PF06260.7 EPE29335.1 - 0.028 14.5 0.2 0.07 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1024) Fork_head PF00250.13 EPE29336.1 - 2.5e-21 75.5 0.2 5.2e-21 74.4 0.2 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EPE29336.1 - 1.1e-05 25.4 0.0 3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain DUF2340 PF10209.4 EPE29336.1 - 0.2 11.8 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) Ten1 PF12658.2 EPE29338.1 - 3.4e-31 107.5 0.0 3.9e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EPE29338.1 - 8.8e-08 31.7 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.6 EPE29338.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Replication factor A protein 3 Snf7 PF03357.16 EPE29339.1 - 4.3e-35 120.6 17.2 4.3e-35 120.6 11.9 2.0 1 1 1 2 2 2 1 Snf7 PAS_10 PF13596.1 EPE29339.1 - 0.09 13.0 0.9 0.39 11.0 0.0 2.2 1 1 1 2 2 2 0 PAS domain DUF3138 PF11336.3 EPE29339.1 - 1.3 7.0 7.2 1.3 7.0 4.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) DUF3508 PF12018.3 EPE29339.1 - 1.6 7.6 8.9 5 6.0 3.9 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3508) Fmp27_WPPW PF10359.4 EPE29339.1 - 7.3 4.8 12.5 5 5.4 7.7 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Peptidase_C2 PF00648.16 EPE29341.1 - 3.7e-45 154.1 0.2 9.8e-33 113.4 0.2 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease Arginase PF00491.16 EPE29342.1 - 2.3e-78 263.3 0.1 2.7e-78 263.0 0.1 1.0 1 0 0 1 1 1 1 Arginase family Imm21 PF15569.1 EPE29342.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 21 YchF-GTPase_C PF06071.8 EPE29345.1 - 3.8e-21 74.6 0.0 9.3e-21 73.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EPE29345.1 - 3.5e-17 62.4 0.0 5.6e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE29345.1 - 5.2e-08 32.3 0.0 1.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF2580 PF10824.3 EPE29347.1 - 0.049 13.9 0.0 0.055 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) GATA PF00320.22 EPE29348.1 - 9.4e-15 53.6 5.2 1.7e-14 52.8 3.6 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 EPE29348.1 - 0.22 11.5 1.9 0.51 10.3 1.3 1.6 1 0 0 1 1 1 0 zinc-finger GCS PF03074.11 EPE29349.1 - 6e-151 502.6 0.0 1.2e-150 501.6 0.0 1.4 1 1 0 1 1 1 1 Glutamate-cysteine ligase SUR7 PF06687.7 EPE29351.1 - 1.4e-18 67.2 9.1 1.4e-18 67.2 6.3 1.6 1 1 1 2 2 2 1 SUR7/PalI family VIT1 PF01988.14 EPE29351.1 - 0.00043 19.8 5.7 0.00066 19.2 4.0 1.3 1 0 0 1 1 1 1 VIT family Claudin_2 PF13903.1 EPE29351.1 - 0.0069 16.0 11.9 0.0069 16.0 8.3 2.3 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.1 EPE29351.1 - 0.019 15.3 6.3 0.059 13.7 0.0 2.7 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain L_HGMIC_fpl PF10242.4 EPE29351.1 - 0.16 12.0 10.8 0.031 14.3 1.2 2.6 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein Wzy_C PF04932.10 EPE29351.1 - 1.1 8.9 4.9 0.22 11.3 0.6 1.8 2 0 0 2 2 2 0 O-Antigen ligase DUF4064 PF13273.1 EPE29351.1 - 2 8.5 10.7 5.4 7.1 2.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Shisa PF13908.1 EPE29351.1 - 3.1 7.9 8.2 1.4 9.0 0.1 2.3 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator zf-C2H2_4 PF13894.1 EPE29352.1 - 1.8e-07 30.9 12.9 0.082 13.2 0.2 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE29352.1 - 0.0021 18.2 16.3 0.44 11.0 0.5 4.4 3 1 0 3 3 3 3 Zinc finger, C2H2 type Raptor_N PF14538.1 EPE29352.1 - 0.0064 16.3 0.1 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain zf-TRAF PF02176.13 EPE29352.1 - 0.034 14.5 0.6 0.15 12.5 0.4 2.2 1 0 0 1 1 1 0 TRAF-type zinc finger zf-H2C2_2 PF13465.1 EPE29352.1 - 0.29 11.4 7.4 4.3 7.8 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 EPE29352.1 - 2.3 8.6 9.4 26 5.3 0.4 4.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Pkinase PF00069.20 EPE29353.1 - 9e-76 254.4 0.0 1.3e-75 253.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29353.1 - 9.2e-40 136.3 0.0 1.4e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EPE29353.1 - 3.4e-14 52.7 0.1 9.2e-14 51.3 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EPE29353.1 - 1.8e-07 30.4 0.0 5.7e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EPE29353.1 - 0.00012 21.4 0.3 0.00026 20.3 0.2 1.5 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EPE29353.1 - 0.0012 17.5 0.1 0.0022 16.6 0.1 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EPE29353.1 - 0.081 12.6 0.2 0.55 9.9 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EPE29353.1 - 0.088 11.8 0.0 0.21 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ndc1_Nup PF09531.5 EPE29353.1 - 1.7 6.9 4.3 2.6 6.3 3.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Gln-synt_C PF00120.19 EPE29355.1 - 1.4e-60 204.6 0.0 1.7e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EPE29355.1 - 8.7e-20 70.0 0.0 1.8e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain KH_3 PF13014.1 EPE29355.1 - 0.08 12.6 0.0 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 KH domain Transp_cyt_pur PF02133.10 EPE29356.1 - 2.4e-152 507.5 38.8 2.7e-152 507.3 26.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GRP PF07172.6 EPE29358.1 - 3.2 8.2 18.4 13 6.3 12.8 2.1 1 0 0 1 1 1 0 Glycine rich protein family CN_hydrolase PF00795.17 EPE29359.1 - 2.2e-30 105.3 0.0 3.6e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Spermine_synth PF01564.12 EPE29360.1 - 5.2e-98 326.8 0.1 6.9e-98 326.4 0.1 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EPE29360.1 - 0.00011 22.7 0.0 0.00022 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE29360.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 EPE29360.1 - 0.0018 17.3 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 EPE29360.1 - 0.02 15.3 0.2 0.25 11.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.13 EPE29360.1 - 0.062 12.4 0.2 0.25 10.5 0.1 1.8 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_30 PF05430.6 EPE29360.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase G-alpha PF00503.15 EPE29362.1 - 4.6e-115 384.4 0.4 5.4e-115 384.2 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EPE29362.1 - 4.7e-14 52.0 1.5 1.1e-09 37.7 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPE29362.1 - 0.00088 18.4 1.3 0.18 10.8 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EPE29362.1 - 0.0048 17.3 0.1 2.5 8.6 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EPE29362.1 - 0.038 13.5 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EPE29362.1 - 0.053 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family zf-U1 PF06220.7 EPE29363.1 - 4.1e-16 58.2 2.1 5.9e-16 57.7 1.4 1.2 1 0 0 1 1 1 1 U1 zinc finger tRNA-synt_2b PF00587.20 EPE29364.1 - 8.5e-47 158.9 0.0 1.3e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPE29364.1 - 4.4e-09 36.1 0.1 9.7e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain HLH PF00010.21 EPE29365.1 - 2.2e-08 33.6 0.2 4.2e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Maf PF02545.9 EPE29366.1 - 4.7e-49 166.1 0.0 6e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein ERG4_ERG24 PF01222.12 EPE29367.1 - 0.12 10.8 0.1 0.18 10.2 0.1 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family HVSL PF09749.4 EPE29368.1 - 1.1e-75 253.7 0.0 1.3e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.6 EPE29369.1 - 1.7e-09 38.2 0.2 9.9e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 Pal1 cell morphology protein DUF3419 PF11899.3 EPE29370.1 - 1.1e-156 521.3 0.1 1.9e-156 520.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EPE29370.1 - 3.7e-11 42.9 0.0 2.2e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE29370.1 - 8.9e-08 32.6 0.0 4.4e-07 30.4 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE29370.1 - 1.4e-07 31.2 0.0 5.9e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE29370.1 - 7.1e-06 26.0 0.0 0.00032 20.6 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE29370.1 - 3.5e-05 24.1 0.0 0.00024 21.5 0.0 2.5 2 1 1 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE29370.1 - 0.00047 20.4 0.0 0.0016 18.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE29370.1 - 0.00076 18.6 0.0 0.017 14.2 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EPE29370.1 - 0.0014 19.0 0.0 0.024 15.1 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain PCMT PF01135.14 EPE29370.1 - 0.0045 16.5 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2391 PF09622.5 EPE29370.1 - 0.012 14.8 0.3 0.024 13.7 0.1 1.5 2 0 0 2 2 2 0 Putative integral membrane protein (DUF2391) Methyltransf_32 PF13679.1 EPE29370.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EPE29370.1 - 0.045 12.7 0.0 0.27 10.2 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_28 PF02636.12 EPE29370.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Noc2 PF03715.8 EPE29371.1 - 3.1e-122 407.1 0.0 8.8e-122 405.6 0.0 1.8 1 0 0 1 1 1 1 Noc2p family PseudoU_synth_2 PF00849.17 EPE29372.1 - 7.5e-29 100.6 0.0 1.3e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.1 EPE29372.1 - 0.038 13.5 0.1 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Mut7-C ubiquitin TGS PF02824.16 EPE29372.1 - 0.11 12.3 0.1 0.36 10.7 0.1 1.8 1 0 0 1 1 1 0 TGS domain GFA PF04828.9 EPE29372.1 - 0.15 12.0 0.0 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme SNF2_N PF00176.18 EPE29373.1 - 7.3e-49 166.1 0.1 1.1e-48 165.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EPE29373.1 - 2.3e-24 85.0 0.7 6.5e-24 83.6 0.5 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EPE29373.1 - 6.1e-11 42.0 0.0 1.1e-09 38.0 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPE29373.1 - 3.9e-05 23.1 0.0 8.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPE29373.1 - 6.5e-05 22.8 0.0 0.00057 19.7 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.1 EPE29373.1 - 0.028 13.2 0.2 4.6 5.9 0.0 2.9 3 0 0 3 3 3 0 P-loop containing NTP hydrolase pore-1 PTS_2-RNA PF01885.11 EPE29374.1 - 5.1e-21 74.8 0.0 7.6e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family zf-CpG_bind_C PF12269.3 EPE29374.1 - 0.14 11.6 0.1 0.47 9.9 0.0 1.7 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain MFS_1 PF07690.11 EPE29375.1 - 6.1e-25 87.6 47.7 2e-23 82.6 16.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE29375.1 - 4.4e-06 25.5 3.0 4.4e-06 25.5 2.1 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EPE29375.1 - 1.7 6.6 12.6 0.51 8.4 0.8 2.7 2 1 0 2 2 2 0 Transmembrane secretion effector PAN_4 PF14295.1 EPE29376.1 - 0.12 12.1 4.2 0.18 11.5 0.5 2.6 2 0 0 2 2 2 0 PAN domain MatE PF01554.13 EPE29377.1 - 8.5e-55 184.7 21.3 9e-30 103.4 4.9 2.3 2 0 0 2 2 2 2 MatE Dispanin PF04505.7 EPE29377.1 - 0.035 13.6 2.2 0.11 12.0 1.5 1.8 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Epimerase PF01370.16 EPE29378.1 - 2.8e-11 43.3 0.0 4.5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE29378.1 - 1.9e-07 31.2 0.0 2.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE29378.1 - 3.8e-05 23.0 0.0 0.00055 19.2 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EPE29378.1 - 0.00055 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EPE29378.1 - 0.013 14.4 0.0 0.07 12.0 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 EPE29378.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 EPE29378.1 - 0.067 11.8 0.0 2.7 6.6 0.0 2.3 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family PhyH PF05721.8 EPE29380.1 - 1.9e-55 188.1 0.0 2.3e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RRM_1 PF00076.17 EPE29381.1 - 5.7e-37 125.1 0.1 1.6e-17 62.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE29381.1 - 1.6e-26 92.0 0.1 3e-12 46.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE29381.1 - 1.2e-11 44.2 1.7 6.9e-05 22.6 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPE29381.1 - 0.14 11.9 2.7 2.9 7.7 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif RabGAP-TBC PF00566.13 EPE29382.1 - 3.2e-48 164.0 0.0 5.2e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SHNi-TPR PF10516.4 EPE29383.1 - 4.9e-15 54.4 0.4 4.9e-15 54.4 0.2 2.8 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.1 EPE29383.1 - 5.8e-08 32.5 1.7 0.0004 20.2 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE29383.1 - 0.00017 22.1 0.1 0.00017 22.1 0.1 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPE29383.1 - 0.00036 20.1 4.7 0.0008 19.0 0.1 2.9 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 EPE29383.1 - 0.0081 16.4 0.1 0.0081 16.4 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPE29383.1 - 0.029 14.2 6.1 0.16 11.9 0.7 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.11 EPE29384.1 - 4e-56 189.5 0.9 4.3e-56 189.4 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B MFS_1 PF07690.11 EPE29386.1 - 2.2e-36 125.3 51.3 2.2e-36 125.3 35.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2937 PF11157.3 EPE29386.1 - 0.056 12.7 2.8 0.4 9.9 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) PgaD PF13994.1 EPE29386.1 - 1.5 8.3 4.0 18 4.8 0.5 2.7 2 0 0 2 2 2 0 PgaD-like protein But2 PF09792.4 EPE29387.1 - 4.8e-30 104.1 1.7 1.2e-29 102.9 1.1 1.7 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain RrnaAD PF00398.15 EPE29388.1 - 2e-58 197.5 0.0 2.7e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EPE29388.1 - 9.1e-11 41.8 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE29388.1 - 6.2e-08 33.2 0.0 1.1e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE29388.1 - 1.7e-05 24.2 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EPE29388.1 - 1.7e-05 24.4 0.0 2.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE29388.1 - 4.8e-05 23.1 0.0 9.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPE29388.1 - 0.00024 20.3 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EPE29388.1 - 0.0003 21.2 0.0 0.00062 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EPE29388.1 - 0.0004 20.0 0.3 0.0007 19.2 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein PCMT PF01135.14 EPE29388.1 - 0.0007 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EPE29388.1 - 0.0012 19.2 0.0 0.0031 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EPE29388.1 - 0.0064 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase NodS PF05401.6 EPE29388.1 - 0.009 15.4 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_25 PF13649.1 EPE29388.1 - 0.0095 16.2 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE29388.1 - 0.043 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EPE29388.1 - 0.046 12.8 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EPE29388.1 - 0.052 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase BNIP2 PF12496.3 EPE29388.1 - 0.12 12.5 0.6 0.22 11.6 0.4 1.4 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Spc97_Spc98 PF04130.8 EPE29389.1 - 1.1e-119 400.1 0.0 1.4e-119 399.8 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3921 PF13060.1 EPE29389.1 - 0.0063 16.3 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3921) SAGA-Tad1 PF12767.2 EPE29390.1 - 3e-61 207.2 0.0 4e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit WD40 PF00400.27 EPE29391.1 - 6.8e-42 139.8 26.6 1.1e-07 31.3 0.1 11.0 11 0 0 11 11 11 9 WD domain, G-beta repeat CPSF_A PF03178.10 EPE29391.1 - 0.011 14.9 0.0 0.17 10.9 0.0 2.3 2 0 0 2 2 2 0 CPSF A subunit region FUSC_2 PF13515.1 EPE29392.1 - 5.6e-26 90.9 7.0 5.6e-26 90.9 4.9 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EPE29392.1 - 2.8e-10 39.4 14.8 0.0013 17.4 0.1 4.5 5 0 0 5 5 5 3 Aluminium activated malate transporter FUSC PF04632.7 EPE29392.1 - 5.1e-05 21.9 17.4 0.00022 19.8 5.5 2.7 2 1 0 2 2 2 2 Fusaric acid resistance protein family DUF2421 PF10334.4 EPE29392.1 - 0.00026 20.6 0.1 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 EPE29392.1 - 6.7 5.3 20.0 0.025 13.3 5.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2422) Dynamin_N PF00350.18 EPE29393.1 - 6.8e-12 45.5 0.1 3.4e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 EPE29393.1 - 7.5e-05 21.9 0.2 0.0005 19.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EPE29393.1 - 0.00013 21.9 0.0 0.0075 16.2 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EPE29393.1 - 0.00015 22.0 0.0 0.0013 19.0 0.0 2.5 2 0 0 2 2 2 1 ABC transporter IIGP PF05049.8 EPE29393.1 - 0.039 12.7 0.0 0.074 11.8 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Tom5 PF10642.4 EPE29394.1 - 1e-21 76.2 0.0 1.1e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase GDC-P PF02347.11 EPE29395.1 - 1.9e-181 603.4 0.0 3.6e-167 556.4 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EPE29395.1 - 3.6e-07 29.6 0.0 6.9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EPE29395.1 - 0.00019 20.2 0.0 0.00084 18.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPE29395.1 - 0.033 13.2 0.0 0.088 11.8 0.0 1.6 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family CHCH PF06747.8 EPE29396.1 - 5.5e-09 35.7 13.5 1.4e-08 34.4 2.4 2.6 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 EPE29396.1 - 0.014 15.1 9.9 0.46 10.2 0.5 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EPE29396.1 - 0.042 13.9 7.0 0.28 11.2 0.7 2.5 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EPE29396.1 - 1.2 9.1 9.3 3.9 7.5 0.4 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DEAD PF00270.24 EPE29397.1 - 8.5e-37 126.2 0.0 2.2e-36 124.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EPE29397.1 - 8.1e-20 70.1 0.0 1.6e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EPE29397.1 - 1.1e-17 63.6 0.0 3.6e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE29397.1 - 0.0046 16.8 1.4 0.046 13.5 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EPE29397.1 - 0.055 13.2 0.0 0.2 11.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain DUF3768 PF12599.3 EPE29398.1 - 0.032 14.1 0.1 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3768) MPLKIP PF15502.1 EPE29398.1 - 0.36 11.5 3.9 0.17 12.6 0.9 1.8 2 0 0 2 2 2 0 M-phase-specific PLK1-interacting protein RNA_pol_Rpb4 PF03874.11 EPE29400.1 - 5.8e-17 61.7 0.3 9.9e-17 61.0 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 GIT1_C PF12205.3 EPE29400.1 - 0.044 13.6 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Trypsin_2 PF13365.1 EPE29400.1 - 0.081 12.9 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Trypsin-like peptidase domain DRY_EERY PF09750.4 EPE29400.1 - 0.42 10.7 3.9 1.6 8.8 0.2 2.2 2 0 0 2 2 2 0 Alternative splicing regulator Pribosyl_synth PF14572.1 EPE29401.1 - 1e-39 136.2 0.8 6.2e-34 117.3 0.1 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EPE29401.1 - 3.2e-29 101.0 0.0 1e-28 99.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EPE29401.1 - 2.3e-11 43.4 0.4 5.7e-11 42.2 0.3 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPE29401.1 - 0.033 13.3 0.1 0.057 12.6 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase WD40 PF00400.27 EPE29403.1 - 3.6e-39 131.2 5.7 2.5e-08 33.5 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 EPE29403.1 - 2.7e-30 104.2 18.7 4.5e-30 103.5 12.9 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 EPE29403.1 - 0.00065 19.4 0.2 10 5.9 0.0 4.4 2 2 3 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 EPE29403.1 - 0.0095 14.2 0.2 0.14 10.3 0.0 2.6 1 1 2 3 3 3 1 Cytochrome D1 heme domain PCI PF01399.22 EPE29404.1 - 6.1e-22 77.9 0.0 1.8e-21 76.4 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 EPE29404.1 - 0.0001 21.8 0.2 0.52 10.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat DDRGK PF09756.4 EPE29404.1 - 0.00067 19.1 1.8 0.001 18.4 0.2 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_16 PF13432.1 EPE29404.1 - 0.0061 17.2 9.7 5.7 7.7 0.3 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Med2 PF11214.3 EPE29404.1 - 0.016 15.2 0.8 0.064 13.2 0.1 2.4 2 0 0 2 2 2 0 Mediator complex subunit 2 TPR_12 PF13424.1 EPE29404.1 - 0.018 14.9 11.6 5.9 6.8 0.4 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EPE29404.1 - 0.063 13.0 0.2 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 DUF627 PF04781.7 EPE29404.1 - 0.086 12.4 0.8 2 8.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_1 PF00515.23 EPE29404.1 - 0.088 12.4 0.9 12 5.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Ras PF00071.17 EPE29406.1 - 5.2e-51 172.2 0.0 1e-50 171.2 0.0 1.5 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.2 EPE29406.1 - 3.2e-34 117.1 0.1 8.3e-18 64.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE29406.1 - 1.2e-26 91.1 12.2 0.00053 19.6 0.1 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EPE29406.1 - 4.3e-21 74.4 2.5 1.2e-07 31.7 0.1 5.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE29406.1 - 4.3e-20 71.6 0.5 5.1e-07 30.0 0.0 4.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Miro PF08477.8 EPE29406.1 - 2e-18 66.9 0.0 1.3e-17 64.3 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Ank_3 PF13606.1 EPE29406.1 - 1.9e-16 58.5 4.4 0.046 13.9 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Abhydrolase_6 PF12697.2 EPE29406.1 - 6.9e-06 26.1 0.0 2e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EPE29406.1 - 0.00018 20.8 0.1 0.0052 16.0 0.1 2.3 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Arf PF00025.16 EPE29406.1 - 0.00024 20.3 0.0 0.00046 19.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family PGAP1 PF07819.8 EPE29406.1 - 0.00047 19.8 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPE29406.1 - 0.00049 19.8 0.0 0.0092 15.7 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family GTP_EFTU PF00009.22 EPE29406.1 - 0.0027 17.1 0.0 0.0092 15.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPE29406.1 - 0.0049 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE29406.1 - 0.053 12.7 0.1 0.34 10.1 0.0 2.3 3 0 0 3 3 3 0 Ferrous iron transport protein B p450 PF00067.17 EPE29407.1 - 2.9e-47 161.2 0.0 5.5e-47 160.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_L44 PF00935.14 EPE29409.1 - 8.4e-35 118.6 11.6 1.4e-34 117.9 8.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 RRM_1 PF00076.17 EPE29410.1 - 6.4e-16 57.7 0.1 1.7e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE29410.1 - 5.4e-13 48.7 0.0 9.8e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE29410.1 - 8.5e-06 25.5 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4646 PF15496.1 EPE29410.1 - 0.00016 21.7 0.0 0.0024 17.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) RRM_3 PF08777.6 EPE29410.1 - 0.93 9.3 0.0 0.93 9.3 0.0 2.4 3 0 0 3 3 3 0 RNA binding motif Abhydrolase_1 PF00561.15 EPE29411.1 - 2.6e-15 56.6 0.0 9.2e-15 54.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EPE29411.1 - 1.7e-14 53.5 0.0 3.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EPE29411.1 - 5.7e-10 39.4 0.0 2.2e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE29411.1 - 0.027 14.2 0.1 0.47 10.1 0.1 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family Pro-kuma_activ PF09286.6 EPE29412.1 - 4.9e-45 153.0 0.1 1.1e-44 151.9 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain WD40 PF00400.27 EPE29413.1 - 3.3e-29 99.6 0.6 1.7e-06 27.7 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EPE29413.1 - 0.13 11.7 0.0 7 6.2 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4066 PF13278.1 EPE29414.1 - 1.2e-21 76.7 0.0 1.5e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EPE29414.1 - 1.8e-09 37.1 0.0 3.8e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family Amidase PF01425.16 EPE29415.1 - 4.6e-68 230.0 0.1 5.8e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Amidase EST1_DNA_bind PF10373.4 EPE29416.1 - 8.1e-17 61.3 0.0 2e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain HET PF06985.6 EPE29417.1 - 1.1e-24 87.2 0.1 2.7e-24 85.9 0.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cupin_2 PF07883.6 EPE29418.1 - 5.7e-05 22.5 0.1 7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.2 EPE29418.1 - 0.077 12.8 0.0 0.18 11.6 0.0 1.5 1 1 0 1 1 1 0 ChrR Cupin-like domain AraC_binding PF02311.14 EPE29418.1 - 0.098 12.3 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain PI-PLC-X PF00388.14 EPE29419.1 - 1.4e-56 189.9 0.3 2.6e-56 189.1 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EPE29419.1 - 6.2e-38 129.4 0.0 2.2e-37 127.6 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF4139 PF13598.1 EPE29419.1 - 0.021 14.1 0.7 0.034 13.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Phosphodiest PF01663.17 EPE29421.1 - 8.2e-87 291.8 0.1 1.1e-86 291.4 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPE29421.1 - 0.00018 20.8 0.1 0.025 13.7 0.0 2.2 1 1 1 2 2 2 2 Sulfatase Herpes_BLLF1 PF05109.8 EPE29421.1 - 1.9 6.3 7.9 2.6 5.8 5.5 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) AA_permease_2 PF13520.1 EPE29422.1 - 7.5e-56 189.4 56.8 1e-55 189.0 39.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE29422.1 - 3.5e-15 55.3 45.0 7.7e-15 54.1 31.2 1.5 1 1 0 1 1 1 1 Amino acid permease HET PF06985.6 EPE29423.1 - 1.3e-33 116.0 1.3 5.5e-33 114.0 0.3 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.18 EPE29424.1 - 6.6e-69 231.9 0.8 9.3e-69 231.4 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE29424.1 - 7.7e-12 44.9 0.0 1.7e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPE29424.1 - 3.3e-06 26.6 0.0 9.2e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase SlyX PF04102.7 EPE29424.1 - 8.7 6.8 16.0 0.043 14.1 3.0 2.9 3 0 0 3 3 3 0 SlyX APH PF01636.18 EPE29427.1 - 3.5e-10 40.0 0.0 3.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE29427.1 - 2.3e-08 33.8 0.0 2.5e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3441 PF11923.3 EPE29430.1 - 4.5e-37 126.0 0.1 4.5e-37 126.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EPE29430.1 - 3.7e-32 111.4 14.2 3.7e-32 111.4 9.8 2.3 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EPE29430.1 - 1.1e-22 79.7 0.0 4e-22 77.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF814) CrtC PF07143.6 EPE29432.1 - 6.2e-15 55.2 0.0 7.6e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Metallophos PF00149.23 EPE29433.1 - 5.7e-11 42.1 0.6 1.6e-10 40.6 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPE29433.1 - 1.5e-08 34.6 1.1 2.6e-08 33.8 0.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2380 PF09533.5 EPE29433.1 - 0.1 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Tannase PF07519.6 EPE29434.1 - 1.8e-99 333.5 0.0 3.6e-99 332.6 0.0 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EPE29434.1 - 0.00064 19.6 0.0 0.0013 18.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE29434.1 - 0.00071 19.3 0.0 0.079 12.7 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE29434.1 - 0.0026 17.3 0.0 0.0073 15.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE29434.1 - 0.039 13.1 0.5 5.6 6.1 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Isy1 PF06246.7 EPE29436.1 - 2.2e-81 273.0 0.0 2.8e-81 272.6 0.0 1.1 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 EPE29436.1 - 0.0094 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 YolD-like protein MMR_HSR1 PF01926.18 EPE29437.1 - 3.1e-14 52.9 0.0 6.8e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPE29437.1 - 2e-05 23.8 0.0 3.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EPE29437.1 - 4.3e-05 22.8 0.0 6.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPE29437.1 - 6.1e-05 22.9 0.5 0.18 11.6 0.0 3.0 2 1 1 3 3 3 2 Dynamin family IIGP PF05049.8 EPE29437.1 - 0.0013 17.6 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EPE29437.1 - 0.0068 16.8 0.2 0.021 15.3 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EPE29437.1 - 0.012 15.9 0.8 0.066 13.5 0.1 2.4 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.11 EPE29437.1 - 0.015 14.3 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AAA_17 PF13207.1 EPE29437.1 - 0.028 15.2 0.2 0.099 13.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain Septin PF00735.13 EPE29437.1 - 0.049 12.6 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Septin SRPRB PF09439.5 EPE29437.1 - 0.1 11.8 0.9 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit HCO3_cotransp PF00955.16 EPE29438.1 - 3.9e-52 177.5 16.3 1e-27 97.0 1.1 2.1 1 1 1 2 2 2 2 HCO3- transporter family Transaldolase PF00923.14 EPE29439.1 - 1.8e-91 306.2 0.2 2e-91 306.0 0.1 1.0 1 0 0 1 1 1 1 Transaldolase CNH PF00780.17 EPE29440.1 - 7.4e-79 265.0 0.0 1.2e-78 264.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EPE29440.1 - 3.6e-26 92.1 0.1 6.8e-26 91.2 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EPE29440.1 - 2.7e-15 56.5 0.1 2.5e-14 53.3 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EPE29440.1 - 1.9e-05 24.8 0.0 5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 PH domain Fungal_trans PF04082.13 EPE29441.1 - 1.1e-25 89.9 0.5 1.7e-25 89.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE29441.1 - 2.5e-05 24.0 2.3 4.5e-05 23.2 1.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 EPE29442.1 - 1.4e-09 37.4 1.4 3.7e-07 29.6 0.2 3.0 2 1 1 3 3 3 2 TPR repeat LRR_4 PF12799.2 EPE29442.1 - 7.7e-08 31.7 1.8 0.6 9.7 0.1 5.8 4 2 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE29442.1 - 2e-06 27.4 2.0 1.6 8.5 0.0 5.6 4 3 1 5 5 5 2 Leucine rich repeat TPR_1 PF00515.23 EPE29442.1 - 6.9e-06 25.4 4.8 0.062 12.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat F-box-like PF12937.2 EPE29442.1 - 5.7e-05 22.7 0.8 0.00012 21.7 0.5 1.6 1 0 0 1 1 1 1 F-box-like TPR_12 PF13424.1 EPE29442.1 - 0.00021 21.1 3.6 0.066 13.1 0.4 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPE29442.1 - 0.00021 20.9 2.9 0.48 10.4 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat LRR_6 PF13516.1 EPE29442.1 - 0.0014 18.4 1.4 15 6.0 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich repeat TPR_9 PF13371.1 EPE29442.1 - 0.0092 15.8 0.1 0.54 10.1 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat F-box PF00646.28 EPE29442.1 - 0.01 15.5 0.2 0.024 14.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain LRR_7 PF13504.1 EPE29442.1 - 0.014 15.4 4.9 31 5.3 0.0 6.1 6 0 0 6 6 6 0 Leucine rich repeat PRANC PF09372.5 EPE29442.1 - 0.033 14.1 0.3 0.097 12.6 0.0 1.9 2 0 0 2 2 2 0 PRANC domain TPR_14 PF13428.1 EPE29442.1 - 0.045 14.4 0.4 0.57 10.9 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPE29442.1 - 0.14 12.9 1.6 0.34 11.6 0.9 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat LRR_1 PF00560.28 EPE29442.1 - 0.75 10.0 7.2 50 4.5 0.4 5.4 5 2 0 5 5 3 0 Leucine Rich Repeat IDO PF01231.13 EPE29443.1 - 1e-174 580.9 0.0 1.2e-174 580.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.8 EPE29444.1 - 4.6e-33 113.4 0.1 2.2e-30 104.8 0.1 2.4 1 1 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EPE29444.1 - 3.1e-21 74.7 0.0 6.3e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 EPE29444.1 - 0.0091 15.4 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF972 PF06156.8 EPE29444.1 - 0.22 11.8 0.2 0.43 10.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) STE2 PF02116.10 EPE29446.1 - 4.7e-45 153.8 21.7 5.5e-45 153.5 15.1 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Abhydrolase_3 PF07859.8 EPE29447.1 - 2.6e-11 43.5 0.2 2e-05 24.2 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE29447.1 - 0.014 15.2 0.1 0.021 14.7 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE29447.1 - 0.026 14.2 0.0 0.037 13.7 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Aminotran_5 PF00266.14 EPE29448.1 - 1.1e-24 86.8 0.0 1.4e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V CRM1_C PF08767.6 EPE29450.1 - 1.4e-134 448.0 0.9 1.4e-134 448.0 0.6 3.4 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 EPE29450.1 - 2.4e-41 141.0 11.6 4.6e-41 140.1 4.6 3.7 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EPE29450.1 - 1.6e-11 43.9 0.2 7.7e-11 41.7 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EPE29450.1 - 0.091 13.1 2.1 2.7 8.4 0.0 4.3 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region DUF3385 PF11865.3 EPE29450.1 - 0.11 12.4 5.5 0.17 11.8 0.0 3.9 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) C8 PF08742.6 EPE29450.1 - 0.25 11.6 1.9 1.3 9.3 0.0 2.9 3 0 0 3 3 3 0 C8 domain Ecl1 PF12855.2 EPE29451.1 - 1.5e-09 36.9 1.5 3.1e-09 35.9 1.0 1.4 1 0 0 1 1 1 1 Life-span regulatory factor Metallothio_Pro PF02069.11 EPE29451.1 - 0.037 13.8 2.1 0.062 13.1 1.4 1.4 1 0 0 1 1 1 0 Prokaryotic metallothionein DNA_processg_A PF02481.10 EPE29452.1 - 0.018 13.9 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 DNA recombination-mediator protein A Med3 PF11593.3 EPE29454.1 - 8.9 5.4 14.6 9.9 5.2 10.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spc7 PF08317.6 EPE29455.1 - 0.027 13.1 17.2 0.14 10.7 3.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein HALZ PF02183.13 EPE29455.1 - 0.75 9.5 12.1 0.42 10.3 1.5 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 EPE29455.1 - 1.1 9.2 15.2 0.83 9.6 2.7 4.0 3 1 1 4 4 4 0 bZIP transcription factor TSC22 PF01166.13 EPE29455.1 - 1.8 8.6 10.4 20 5.2 2.1 3.6 2 2 1 3 3 3 0 TSC-22/dip/bun family DUF87 PF01935.12 EPE29455.1 - 5.5 6.7 9.4 0.19 11.5 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF87 Peptidase_M20 PF01546.23 EPE29457.1 - 1.6e-07 30.9 0.3 2.4e-07 30.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPE29457.1 - 0.049 13.3 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Peptidase dimerisation domain MFS_1 PF07690.11 EPE29458.1 - 4.5e-29 101.2 36.6 5.9e-29 100.8 25.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_18 PF00704.23 EPE29459.1 - 6.5e-17 61.9 0.2 1.7e-15 57.3 0.0 2.1 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 Big_3_2 PF12245.3 EPE29459.1 - 0.0056 16.2 0.7 1.2 8.7 0.0 3.9 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 3) SKG6 PF08693.5 EPE29460.1 - 9.8e-08 31.1 4.2 3e-07 29.6 2.9 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EPE29460.1 - 0.0058 16.1 1.1 0.013 14.9 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF4448) CcmD PF04995.9 EPE29460.1 - 0.052 13.2 1.6 0.11 12.2 1.1 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Rax2 PF12768.2 EPE29460.1 - 0.094 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Shugoshin_N PF07558.6 EPE29461.1 - 1.5e-12 47.0 4.9 1.6e-12 46.8 2.1 2.2 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EPE29461.1 - 9e-12 44.2 4.4 9e-12 44.2 3.0 3.9 3 0 0 3 3 3 1 Shugoshin C terminus DUF3405 PF11885.3 EPE29461.1 - 0.04 12.1 0.1 0.065 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) DASH_Dad2 PF08654.5 EPE29462.1 - 3.8e-36 123.1 0.7 4.7e-36 122.8 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 COesterase PF00135.23 EPE29464.1 - 2.7e-98 330.0 0.0 3.6e-98 329.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE29464.1 - 0.00066 19.3 1.4 0.0053 16.3 1.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold SKG6 PF08693.5 EPE29465.1 - 0.0074 15.5 1.8 0.014 14.7 1.3 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain OB_NTP_bind PF07717.11 EPE29466.1 - 3.7e-22 78.3 0.0 7.2e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPE29466.1 - 1.8e-21 76.0 0.0 3.4e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPE29466.1 - 4.4e-12 45.6 0.0 8.8e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPE29466.1 - 1.8e-06 28.0 0.0 4.7e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EPE29466.1 - 8.5e-05 22.1 0.1 0.00019 20.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_33 PF13671.1 EPE29466.1 - 0.013 15.4 0.0 0.097 12.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 EPE29466.1 - 0.017 14.0 0.1 0.037 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 EPE29466.1 - 0.018 14.5 0.1 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EPE29466.1 - 0.031 13.8 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EPE29466.1 - 0.034 13.2 0.3 0.14 11.2 0.1 2.1 1 1 1 2 2 2 0 Zeta toxin AAA_10 PF12846.2 EPE29466.1 - 0.038 13.4 0.5 0.38 10.1 0.3 2.5 1 1 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EPE29466.1 - 0.042 13.7 0.3 3.6 7.5 0.2 2.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EPE29466.1 - 0.21 11.8 0.5 0.59 10.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain Glyco_hydro_76 PF03663.9 EPE29468.1 - 9.4e-147 489.2 13.9 1.2e-146 488.8 9.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Sdh5 PF03937.11 EPE29470.1 - 9.9e-23 79.6 0.4 1.9e-22 78.7 0.3 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Nebulin PF00880.13 EPE29471.1 - 0.016 14.8 0.2 0.052 13.1 0.1 1.9 1 0 0 1 1 1 0 Nebulin repeat DUF3433 PF11915.3 EPE29472.1 - 1.9e-45 152.9 6.8 4.1e-27 94.1 0.3 3.7 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Peptidase_C74 PF12387.3 EPE29472.1 - 0.062 12.4 0.1 0.93 8.6 0.0 2.2 2 0 0 2 2 2 0 Pestivirus NS2 peptidase PIG-F PF06699.6 EPE29473.1 - 2.7e-55 187.2 6.4 3.3e-55 186.9 4.4 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Bacteriocin_IIc PF10439.4 EPE29473.1 - 0.011 15.8 4.0 0.89 9.7 0.2 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Ank_2 PF12796.2 EPE29474.1 - 1.7e-40 137.2 6.7 2.6e-12 46.8 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) SPX PF03105.14 EPE29474.1 - 1.2e-26 94.1 13.5 1e-13 51.7 3.2 3.0 2 1 1 3 3 3 2 SPX domain Ank PF00023.25 EPE29474.1 - 1.7e-23 81.1 11.8 0.00034 20.2 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 EPE29474.1 - 7e-23 80.5 4.2 1e-06 29.0 0.0 6.5 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE29474.1 - 1.1e-15 56.1 7.7 0.0017 18.3 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 EPE29474.1 - 1.6e-14 53.5 7.9 0.001 19.2 0.0 6.2 3 1 4 7 7 7 6 Ankyrin repeats (many copies) CUE PF02845.11 EPE29474.1 - 2.1e-13 49.4 0.0 7e-13 47.7 0.0 2.0 1 0 0 1 1 1 1 CUE domain GDPD PF03009.12 EPE29474.1 - 4.1e-07 29.7 0.0 2e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Rsa3 PF14615.1 EPE29474.1 - 0.27 10.5 2.6 1.4 8.2 0.1 2.9 3 0 0 3 3 3 0 Ribosome-assembly protein 3 Enkurin PF13864.1 EPE29475.1 - 0.0032 17.6 0.2 0.0066 16.6 0.2 1.5 1 0 0 1 1 1 1 Calmodulin-binding MRP-S26 PF14943.1 EPE29475.1 - 0.14 11.7 1.1 0.23 10.9 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Coa1 PF08695.5 EPE29476.1 - 1.1e-37 128.0 0.0 1.4e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L3 PF00297.17 EPE29477.1 - 2.3e-33 115.7 5.0 5.5e-32 111.1 3.4 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 DUF814 PF05670.8 EPE29478.1 - 9.6e-20 70.2 0.1 4.2e-19 68.2 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF814) ATP-synt_E PF05680.7 EPE29478.1 - 8 6.4 9.0 15 5.6 6.2 1.4 1 0 0 1 1 1 0 ATP synthase E chain PITH PF06201.8 EPE29479.1 - 3.9e-48 163.0 0.1 4.7e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 PITH domain AA_permease PF00324.16 EPE29481.1 - 4.7e-126 420.9 37.2 5.7e-126 420.6 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE29481.1 - 7.8e-34 116.9 40.5 1.1e-33 116.4 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease Adeno_E3_14_5 PF04834.7 EPE29481.1 - 0.17 12.3 3.7 2.1 8.8 1.2 2.8 2 0 0 2 2 2 0 Early E3 14.5 kDa protein HhH-GPD PF00730.20 EPE29482.1 - 6.2e-18 65.0 0.0 1.3e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EPE29482.1 - 7.6e-07 28.4 0.0 1.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Amino_oxidase PF01593.19 EPE29483.1 - 1.1e-41 143.4 0.1 3.9e-24 85.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPE29483.1 - 6.7e-15 54.8 0.0 1.3e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE29483.1 - 6.9e-06 25.1 0.1 2.7e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPE29483.1 - 2.4e-05 23.0 0.3 0.0059 15.1 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 EPE29483.1 - 2.8e-05 24.4 0.2 8.9e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE29483.1 - 9.4e-05 22.5 0.0 0.0035 17.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPE29483.1 - 0.00029 20.0 0.3 0.00043 19.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EPE29483.1 - 0.00036 19.7 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EPE29483.1 - 0.0011 17.9 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EPE29483.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EPE29483.1 - 0.016 14.8 0.2 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EPE29483.1 - 0.028 14.2 3.1 2.1 8.1 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 EPE29483.1 - 0.086 11.6 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Rossmann-like PF10727.4 EPE29483.1 - 0.088 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain FAD_oxidored PF12831.2 EPE29483.1 - 0.17 10.9 0.1 0.29 10.1 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GDPD PF03009.12 EPE29484.1 - 1.1e-32 113.6 0.0 1.6e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EPE29484.1 - 0.0027 17.8 0.1 0.0092 16.1 0.1 2.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SseC PF04888.7 EPE29485.1 - 0.054 12.8 0.9 0.093 12.0 0.6 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family SET PF00856.23 EPE29487.1 - 0.00081 19.7 0.0 0.0031 17.8 0.0 2.0 1 1 0 1 1 1 1 SET domain Fungal_trans PF04082.13 EPE29488.1 - 8.9e-34 116.5 0.9 1.6e-33 115.6 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MMR_HSR1_C PF08438.5 EPE29490.1 - 4.4e-33 113.7 0.0 9.8e-33 112.6 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EPE29490.1 - 2.2e-18 66.3 0.0 6.3e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE29490.1 - 1.1e-09 37.7 0.1 1.9e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EPE29490.1 - 0.00041 19.8 0.0 0.2 11.0 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EPE29490.1 - 0.0054 16.3 0.1 1.3 8.4 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 EPE29490.1 - 0.012 15.4 1.8 0.16 11.7 0.2 2.6 3 0 0 3 3 3 0 Dynamin family ABC_tran PF00005.22 EPE29490.1 - 0.015 15.6 0.1 0.55 10.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter VirB8 PF04335.8 EPE29490.1 - 0.021 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 VirB8 protein ArgK PF03308.11 EPE29490.1 - 0.041 12.6 0.1 0.22 10.2 0.0 2.1 2 0 0 2 2 2 0 ArgK protein KTI12 PF08433.5 EPE29490.1 - 0.087 12.0 0.0 0.22 10.6 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Pmp3 PF01679.12 EPE29491.1 - 4.5e-27 93.5 5.8 4.9e-27 93.3 4.0 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 EPE29491.1 - 0.6 9.8 4.3 0.28 10.8 1.0 1.7 2 0 0 2 2 2 0 Conserved TM helix Ribosomal_L22e PF01776.12 EPE29492.1 - 1.4e-48 163.4 1.0 1.6e-48 163.3 0.7 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Glyco_transf_8 PF01501.15 EPE29493.1 - 5.8e-19 68.4 0.0 7.7e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.22 EPE29494.1 - 6.4e-55 182.8 1.6 1.1e-18 66.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Kinase-like PF14531.1 EPE29494.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Nucleopor_Nup85 PF07575.8 EPE29495.1 - 2.7e-07 29.1 1.5 0.036 12.2 0.0 4.3 4 1 0 4 4 4 4 Nup85 Nucleoporin Tubulin PF00091.20 EPE29496.1 - 4.5e-73 245.6 0.0 6.7e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPE29496.1 - 5.3e-47 158.9 0.6 8.1e-47 158.3 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EPE29496.1 - 1.2e-07 31.8 0.0 2.5e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain MgsA_C PF12002.3 EPE29499.1 - 2e-60 203.2 0.0 3.3e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EPE29499.1 - 2.5e-12 47.1 0.0 7.7e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPE29499.1 - 9.4e-09 34.6 0.0 2.1e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EPE29499.1 - 4.3e-06 26.0 0.1 0.026 13.7 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPE29499.1 - 9.2e-05 22.1 0.0 0.0031 17.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EPE29499.1 - 9.5e-05 21.9 0.1 0.01 15.2 0.0 2.6 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 EPE29499.1 - 0.00023 21.2 0.1 0.00072 19.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EPE29499.1 - 0.00037 20.1 0.0 0.0013 18.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EPE29499.1 - 0.0016 18.1 0.0 0.0048 16.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EPE29499.1 - 0.0052 15.7 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 EPE29499.1 - 0.0097 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 EPE29499.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPE29499.1 - 0.026 14.5 0.6 0.2 11.6 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain TIP49 PF06068.8 EPE29499.1 - 0.033 12.9 0.0 0.42 9.2 0.0 2.0 2 0 0 2 2 2 0 TIP49 C-terminus AAA_18 PF13238.1 EPE29499.1 - 0.046 14.0 0.4 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 EPE29499.1 - 0.05 13.4 0.1 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.1 EPE29499.1 - 0.055 13.4 0.3 0.17 11.7 0.2 1.9 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EPE29499.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Lipase_3 PF01764.20 EPE29501.1 - 1.1e-28 99.5 0.0 1.6e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EPE29501.1 - 6e-05 22.7 0.0 8.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPE29501.1 - 0.00045 19.9 0.0 0.00061 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE29501.1 - 0.0025 17.7 2.7 0.0064 16.3 1.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EPE29501.1 - 0.0066 16.7 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 EPE29501.1 - 0.015 14.8 0.2 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 EPE29501.1 - 0.072 11.5 0.1 0.12 10.8 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2048 PF09752.4 EPE29501.1 - 0.081 11.7 0.2 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF2974 PF11187.3 EPE29501.1 - 0.1 11.9 1.1 0.18 11.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) LCAT PF02450.10 EPE29501.1 - 0.2 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase F-box PF00646.28 EPE29502.1 - 0.00046 19.7 0.5 0.00046 19.7 0.4 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EPE29502.1 - 0.0044 16.7 0.3 0.014 15.0 0.2 2.0 1 0 0 1 1 1 1 F-box-like FAD_binding_4 PF01565.18 EPE29503.1 - 3.3e-09 36.3 0.0 4.5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF1279 PF06916.8 EPE29504.1 - 8.8e-13 48.3 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF1869 PF08956.5 EPE29504.1 - 0.03 13.9 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) TrbH PF07283.6 EPE29504.1 - 0.069 13.0 0.1 7.6 6.4 0.0 2.1 1 1 1 2 2 2 0 Conjugal transfer protein TrbH Pectinesterase PF01095.14 EPE29506.1 - 5.7e-45 153.1 11.7 7.4e-45 152.7 8.1 1.1 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_46 PF01374.13 EPE29506.1 - 0.034 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 Glyco_hydro_28 PF00295.12 EPE29507.1 - 5.3e-107 357.5 22.8 6.2e-107 357.3 15.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Sugar_tr PF00083.19 EPE29508.1 - 6.9e-110 367.7 15.6 9.5e-110 367.2 10.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE29508.1 - 3.4e-26 91.7 26.9 3.4e-26 91.7 18.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPE29508.1 - 3.2e-06 25.6 2.5 5.3e-06 24.9 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.14 EPE29508.1 - 0.0025 16.4 5.1 0.23 9.9 0.6 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_1_like PF12832.2 EPE29508.1 - 0.0044 16.7 0.4 2.1 8.1 0.1 3.7 3 0 0 3 3 3 1 MFS_1 like family PspC PF04024.7 EPE29508.1 - 0.47 9.9 5.7 0.32 10.4 0.7 3.1 2 0 0 2 2 2 0 PspC domain AIP3 PF03915.8 EPE29509.1 - 5.6e-158 526.3 9.5 9.3e-158 525.5 6.6 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 FliL PF03748.9 EPE29509.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.8 3 0 0 3 3 3 0 Flagellar basal body-associated protein FliL Lectin_N PF03954.9 EPE29509.1 - 0.93 8.8 8.4 0.19 11.1 0.3 3.3 4 0 0 4 4 4 0 Hepatic lectin, N-terminal domain Syntaxin_2 PF14523.1 EPE29509.1 - 3.6 7.6 10.3 3.3 7.8 0.0 3.9 4 0 0 4 4 4 0 Syntaxin-like protein LsmAD PF06741.8 EPE29510.1 - 1.7e-25 88.8 1.1 3.4e-25 87.9 0.8 1.5 1 0 0 1 1 1 1 LsmAD domain DNA_binding_1 PF01035.15 EPE29511.1 - 8e-23 79.9 0.3 1.7e-22 78.9 0.2 1.5 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain FAD_binding_4 PF01565.18 EPE29513.1 - 8.5e-19 67.4 0.4 1.7e-18 66.4 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE29513.1 - 1.8e-09 37.3 0.0 4.9e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like PPI_Ypi1 PF07491.6 EPE29514.1 - 3.5e-18 64.9 8.2 5.6e-10 38.7 0.0 2.9 3 1 0 3 3 3 2 Protein phosphatase inhibitor CDC45 PF02724.9 EPE29514.1 - 0.21 9.5 3.1 0.29 9.1 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 EPE29514.1 - 1.3 7.2 6.9 1.5 7.0 4.7 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2201_N PF13203.1 EPE29514.1 - 1.4 8.0 9.5 4 6.5 0.1 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain SelP_N PF04592.9 EPE29514.1 - 1.9 7.8 5.4 3 7.1 3.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MFS_1 PF07690.11 EPE29515.1 - 1.8e-38 132.1 40.2 1.8e-38 132.1 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ACOX PF01756.14 EPE29516.1 - 1.7e-35 122.1 0.1 3.2e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EPE29516.1 - 4.1e-24 85.2 0.2 8.8e-24 84.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EPE29516.1 - 2.4e-12 46.1 0.8 6.4e-12 44.7 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EPE29516.1 - 1.8e-06 28.1 0.0 0.035 14.2 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain RGS PF00615.14 EPE29517.1 - 3.5e-06 27.1 0.0 0.00015 21.8 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Aldolase_II PF00596.16 EPE29518.1 - 4.5e-43 146.9 0.1 6.1e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.11 EPE29520.1 - 9.1e-30 103.5 53.5 7.9e-26 90.5 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE29520.1 - 1.1e-20 73.6 26.9 2.8e-17 62.4 3.1 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter SH3_9 PF14604.1 EPE29521.1 - 4.3e-13 48.6 0.0 8.7e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 EPE29521.1 - 1.6e-11 43.8 0.0 2.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 EPE29521.1 - 6.1e-11 41.5 0.0 1.4e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EPE29521.1 - 4.2e-09 36.5 0.0 1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EPE29521.1 - 1.1e-05 25.6 0.0 2.9e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 EPE29521.1 - 1.2e-05 24.7 0.0 2.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EPE29521.1 - 0.052 13.7 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EPE29521.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain zf-MIZ PF02891.15 EPE29522.1 - 9.5e-11 41.0 1.9 2.4e-10 39.7 1.3 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EPE29522.1 - 0.00018 20.9 0.5 0.00044 19.6 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DnaJ PF00226.26 EPE29523.1 - 3.2e-13 49.1 0.0 4.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain SHS2_Rpb7-N PF03876.12 EPE29524.1 - 8.1e-07 29.0 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF3807 PF12720.2 EPE29524.1 - 2.8 8.0 9.6 7 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) GAF_2 PF13185.1 EPE29525.1 - 1.8e-07 31.7 0.0 5.2e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EPE29525.1 - 9e-05 22.6 0.0 0.00013 22.0 0.0 1.3 1 1 0 1 1 1 1 GAF domain Arrestin_N PF00339.24 EPE29527.1 - 2.9e-18 66.1 0.2 6e-11 42.3 0.0 2.7 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EPE29527.1 - 0.028 13.6 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus Las1 PF04031.8 EPE29529.1 - 6.5e-56 188.2 0.0 1.2e-55 187.3 0.0 1.5 1 0 0 1 1 1 1 Las1-like zf-RING_5 PF14634.1 EPE29530.1 - 0.0012 18.5 5.3 0.004 16.8 3.7 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPE29530.1 - 0.0015 18.5 0.7 0.0015 18.5 0.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE29530.1 - 0.0063 16.1 3.4 0.02 14.5 2.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EPE29530.1 - 0.053 13.5 0.4 0.053 13.5 0.3 2.2 2 0 0 2 2 2 0 zinc-finger zf-C3HC4_3 PF13920.1 EPE29530.1 - 0.06 13.0 4.0 0.14 11.8 1.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE29530.1 - 0.091 12.6 2.5 0.19 11.5 0.5 2.1 2 0 0 2 2 2 0 Ring finger domain zf-B_box PF00643.19 EPE29530.1 - 0.13 12.2 5.3 4.2 7.3 0.1 2.5 2 0 0 2 2 2 0 B-box zinc finger zf-C3HC4_4 PF15227.1 EPE29530.1 - 0.21 11.5 1.8 0.62 9.9 0.3 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.16 EPE29530.1 - 1.3 9.0 6.5 6.9 6.6 4.5 2.0 1 1 0 1 1 1 0 FYVE zinc finger Prp19 PF08606.6 EPE29531.1 - 3.8e-35 119.4 0.9 8.3e-35 118.3 0.6 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EPE29531.1 - 7.3e-15 54.2 1.8 0.0001 22.0 0.0 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EPE29531.1 - 0.00026 19.9 0.0 0.23 10.1 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 EPE29531.1 - 0.00037 20.2 0.0 0.025 14.3 0.0 2.5 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A U-box PF04564.10 EPE29531.1 - 0.00047 20.0 0.0 0.0016 18.3 0.0 1.8 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 EPE29531.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit OHCU_decarbox PF09349.5 EPE29532.1 - 3.8e-38 131.2 0.8 5.9e-25 88.4 0.0 2.0 2 0 0 2 2 2 2 OHCU decarboxylase HILPDA PF15220.1 EPE29532.1 - 0.052 13.5 0.0 6.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated FLgD_tudor PF13861.1 EPE29532.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 FlgD Tudor-like domain WD40 PF00400.27 EPE29535.1 - 4.7e-24 83.3 12.0 4.4e-10 39.0 0.1 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EPE29535.1 - 2.5e-18 65.7 0.0 5.6e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Ribosomal_S6 PF01250.12 EPE29536.1 - 1.6e-10 40.7 0.0 1.9e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Cullin_binding PF03556.10 EPE29537.1 - 5e-31 107.2 5.4 7.2e-31 106.7 3.7 1.2 1 0 0 1 1 1 1 Cullin binding PX PF00787.19 EPE29538.1 - 1.7e-17 63.2 0.1 3.8e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.1 EPE29538.1 - 0.11 12.2 0.2 0.11 12.2 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit APH PF01636.18 EPE29539.1 - 6.8e-07 29.2 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L18e PF00828.14 EPE29540.1 - 1.7e-16 60.7 0.3 2.7e-16 60.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Glyco_transf_90 PF05686.7 EPE29541.1 - 5.8e-12 45.0 4.9 4.1e-10 38.9 1.0 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF2422 PF10337.4 EPE29542.1 - 3.5e-97 326.0 2.3 2e-96 323.6 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EPE29542.1 - 1.1e-15 57.6 14.9 1.1e-15 57.6 10.3 3.0 2 2 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EPE29542.1 - 4e-06 26.6 0.0 6.3e-05 22.7 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EPE29542.1 - 0.16 10.5 10.2 0.7 8.4 7.1 2.0 1 1 0 1 1 1 0 Aluminium activated malate transporter Chs3p PF12271.3 EPE29543.1 - 1.6e-137 457.3 22.8 1.8e-137 457.1 15.8 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit MpPF26 PF07666.6 EPE29543.1 - 4.4 7.1 17.4 3.8 7.4 6.6 2.8 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF3382 PF11862.3 EPE29543.1 - 8.2 6.4 11.6 1.1 9.2 4.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) Cyclin PF08613.6 EPE29544.1 - 2.6e-18 66.8 0.1 4.1e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EPE29544.1 - 0.00024 20.6 0.1 0.00042 19.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain PGAP1 PF07819.8 EPE29545.1 - 9.5e-05 22.0 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPE29545.1 - 0.00039 20.1 0.1 0.0015 18.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EPE29545.1 - 0.00054 19.3 0.0 0.0017 17.6 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF2730 PF10805.3 EPE29545.1 - 0.0048 16.5 0.5 0.0097 15.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Abhydrolase_6 PF12697.2 EPE29545.1 - 0.01 15.7 0.1 0.022 14.6 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3420 PF11900.3 EPE29545.1 - 0.013 15.6 0.0 0.038 14.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) Abhydrolase_2 PF02230.11 EPE29545.1 - 0.069 12.5 0.0 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Aldedh PF00171.17 EPE29546.1 - 3.3e-153 510.3 0.0 4.1e-153 510.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 EPE29547.1 - 2.2e-53 181.3 0.0 3.1e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE29547.1 - 5.6e-41 140.1 0.1 9.1e-41 139.5 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EPE29547.1 - 0.00017 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPE29547.1 - 0.00021 21.2 0.0 0.00072 19.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE29547.1 - 0.00062 18.7 0.0 0.0026 16.7 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE29547.1 - 0.0084 14.9 0.0 0.92 8.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EPE29547.1 - 0.013 15.3 0.0 0.07 12.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EPE29547.1 - 0.024 13.2 0.1 0.057 12.0 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase DUF498 PF04430.9 EPE29548.1 - 5e-30 103.2 0.0 7e-30 102.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) ILVD_EDD PF00920.16 EPE29549.1 - 3.9e-200 665.7 3.6 4.5e-200 665.5 2.5 1.0 1 0 0 1 1 1 1 Dehydratase family Abhydrolase_6 PF12697.2 EPE29550.1 - 3e-24 86.1 0.1 5.5e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE29550.1 - 2.9e-16 59.5 0.0 1.3e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 EPE29550.1 - 7.9e-10 38.4 0.0 1.9e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 EPE29550.1 - 1.5e-08 34.4 0.0 3.4e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold PTPlike_phytase PF14566.1 EPE29550.1 - 3.3e-05 23.9 0.0 6.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Thioesterase PF00975.15 EPE29550.1 - 0.0001 22.5 0.2 0.00029 21.1 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Y_phosphatase PF00102.22 EPE29550.1 - 0.00042 19.7 0.0 0.00086 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ser_hydrolase PF06821.8 EPE29550.1 - 0.00073 19.1 0.0 0.014 14.9 0.0 2.7 3 0 0 3 3 3 1 Serine hydrolase PGAP1 PF07819.8 EPE29550.1 - 0.0016 18.1 0.1 0.0051 16.4 0.1 1.8 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EPE29550.1 - 0.0076 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Esterase_phd PF10503.4 EPE29550.1 - 0.061 12.5 0.8 0.81 8.8 0.2 2.4 2 1 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 EPE29550.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1749 PF08538.5 EPE29550.1 - 0.086 11.7 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF2305 PF10230.4 EPE29550.1 - 0.12 11.7 0.1 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_2 PF02230.11 EPE29550.1 - 0.18 11.2 0.0 15 4.9 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase MafB19-deam PF14437.1 EPE29551.1 - 0.023 14.3 0.0 0.071 12.7 0.0 1.8 2 0 0 2 2 2 0 MafB19-like deaminase MAP65_ASE1 PF03999.7 EPE29552.1 - 4.8e-72 243.4 8.0 4.8e-72 243.4 5.5 1.4 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) LemA PF04011.7 EPE29552.1 - 0.064 12.3 0.1 0.17 10.9 0.1 1.7 1 0 0 1 1 1 0 LemA family Sipho_Gp157 PF05565.6 EPE29552.1 - 2.3 7.7 9.1 0.11 12.0 0.5 2.8 3 0 0 3 3 3 0 Siphovirus Gp157 JAB PF01398.16 EPE29553.1 - 5.8e-30 103.3 0.0 1.9e-28 98.4 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EPE29553.1 - 3.3e-06 26.6 0.0 7.5e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain tRNA-synt_1c PF00749.16 EPE29554.1 - 1.3e-96 323.0 0.0 1.6e-96 322.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.13 EPE29554.1 - 0.037 12.7 0.0 21 3.6 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetases class I (K) Ribosomal_L32e PF01655.13 EPE29555.1 - 2.2e-47 159.6 1.4 4.9e-47 158.5 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L32 CTDII PF01556.13 EPE29555.1 - 9.4e-21 73.5 0.4 5.9e-18 64.5 0.0 3.4 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 EPE29555.1 - 2.5e-20 71.9 2.8 5.3e-20 70.9 1.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EPE29555.1 - 6.5e-15 54.9 18.4 1.2e-14 54.0 12.8 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EPE29555.1 - 0.0042 16.7 7.7 0.34 10.6 1.0 2.6 2 1 0 2 2 2 2 Hydrogenase expression/synthesis hypA family UreE_N PF02814.10 EPE29555.1 - 0.09 12.2 0.1 0.38 10.3 0.0 2.1 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain GCC2_GCC3 PF07699.8 EPE29555.1 - 2.2 7.9 12.2 1.3 8.6 0.9 2.4 2 0 0 2 2 2 0 GCC2 and GCC3 DUF1356 PF07092.7 EPE29555.1 - 4.2 6.4 6.1 14 4.7 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1356) Sec2p PF06428.6 EPE29556.1 - 5.8e-10 38.9 6.3 5.8e-10 38.9 4.4 2.3 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Jnk-SapK_ap_N PF09744.4 EPE29556.1 - 0.00012 22.1 11.2 0.011 15.7 1.3 2.1 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 ATG16 PF08614.6 EPE29556.1 - 0.00039 20.2 15.9 0.0056 16.5 6.0 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) IncA PF04156.9 EPE29556.1 - 0.003 17.1 15.5 0.02 14.4 3.1 2.1 2 0 0 2 2 2 2 IncA protein DUF4407 PF14362.1 EPE29556.1 - 0.011 14.6 6.1 0.23 10.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.7 EPE29556.1 - 0.013 15.2 2.2 0.013 15.2 1.5 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EPE29556.1 - 0.039 12.8 9.3 0.078 11.9 0.2 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PBC PF03792.8 EPE29556.1 - 0.061 12.9 6.3 0.061 13.0 1.3 2.1 2 0 0 2 2 2 0 PBC domain SlyX PF04102.7 EPE29556.1 - 0.075 13.4 14.3 0.21 11.9 0.8 3.8 2 2 1 3 3 3 0 SlyX CENP-F_leu_zip PF10473.4 EPE29556.1 - 0.083 12.7 14.2 0.46 10.3 4.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 EPE29556.1 - 0.16 9.7 10.2 0.24 9.1 1.4 2.0 2 0 0 2 2 2 0 HOOK protein YlqD PF11068.3 EPE29556.1 - 0.19 11.7 11.1 2.1 8.3 0.7 2.1 2 0 0 2 2 2 0 YlqD protein DUF3373 PF11853.3 EPE29556.1 - 0.26 9.7 3.2 2.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) MRP-L28 PF09812.4 EPE29556.1 - 0.59 9.9 11.0 2.7 7.7 0.3 2.9 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L28 DUF148 PF02520.12 EPE29556.1 - 0.79 9.5 9.4 0.045 13.5 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF2894 PF11445.3 EPE29556.1 - 0.82 9.9 12.2 2.1 8.5 8.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) DUF2968 PF11180.3 EPE29556.1 - 0.99 8.7 20.6 0.52 9.6 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Tup_N PF08581.5 EPE29556.1 - 1 9.5 6.2 1.5 9.0 0.5 2.4 2 0 0 2 2 2 0 Tup N-terminal ERM PF00769.14 EPE29556.1 - 1.2 8.5 19.6 0.43 10.0 2.5 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family BLOC1_2 PF10046.4 EPE29556.1 - 1.5 9.0 5.8 3.6 7.7 0.4 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.16 EPE29556.1 - 2 8.4 9.5 1 9.3 0.1 3.2 2 1 1 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 EPE29556.1 - 2.9 8.2 6.8 2.8 8.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Spc7 PF08317.6 EPE29556.1 - 4.4 5.8 13.3 0.64 8.6 1.9 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein Phlebovirus_NSM PF07246.6 EPE29556.1 - 5.3 6.1 5.6 0.96 8.5 0.1 1.9 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Laminin_I PF06008.9 EPE29556.1 - 6 6.0 14.9 0.58 9.4 1.9 2.1 2 0 0 2 2 2 0 Laminin Domain I UPRTase PF14681.1 EPE29557.1 - 4.1e-73 245.0 0.0 4.7e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EPE29557.1 - 2.3e-07 30.5 0.0 3.5e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain P5CR_dimer PF14748.1 EPE29557.1 - 0.04 13.9 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation CRCB PF02537.10 EPE29558.1 - 2.4e-32 111.2 18.8 7.1e-21 74.2 3.5 3.9 4 0 0 4 4 4 3 CrcB-like protein Peptidase_S28 PF05577.7 EPE29559.1 - 2e-48 165.0 1.1 7.4e-48 163.1 0.7 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Thioredoxin PF00085.15 EPE29560.1 - 2e-62 207.3 0.2 7.1e-30 102.7 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EPE29560.1 - 3.4e-25 88.4 0.1 3.4e-25 88.4 0.0 2.7 4 0 0 4 4 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EPE29560.1 - 7.7e-20 71.1 0.1 2.5e-09 37.3 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EPE29560.1 - 2.2e-17 62.8 0.0 2e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EPE29560.1 - 3.1e-13 49.6 0.1 1.5e-05 25.0 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.1 EPE29560.1 - 6e-10 39.2 0.1 0.001 18.9 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EPE29560.1 - 3.7e-09 36.3 0.2 0.0016 18.0 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EPE29560.1 - 3.9e-06 26.4 2.1 0.0032 17.0 0.1 2.3 1 1 1 2 2 2 2 Redoxin ERp29_N PF07912.8 EPE29560.1 - 7.8e-06 25.8 0.2 0.0038 17.1 0.0 2.7 3 0 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_9 PF14595.1 EPE29560.1 - 9.6e-06 25.1 0.0 0.0037 16.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.1 EPE29560.1 - 5e-05 23.0 0.0 0.26 11.1 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_4 PF13462.1 EPE29560.1 - 8.3e-05 22.6 1.1 3 7.8 0.1 4.0 2 2 2 4 4 4 2 Thioredoxin HyaE PF07449.6 EPE29560.1 - 0.0014 18.5 0.0 0.0095 15.8 0.0 2.1 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE DSBA PF01323.15 EPE29560.1 - 0.002 17.7 1.8 4.7 6.7 0.1 4.0 3 1 1 4 4 4 1 DSBA-like thioredoxin domain TraF PF13728.1 EPE29560.1 - 0.036 13.5 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 F plasmid transfer operon protein DDE_Tnp_1_2 PF13586.1 EPE29560.1 - 0.05 13.7 0.0 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain Glutaredoxin PF00462.19 EPE29560.1 - 0.27 11.2 3.0 8.8 6.4 0.1 3.1 2 2 0 2 2 2 0 Glutaredoxin HSBP1 PF06825.7 EPE29561.1 - 4.9e-18 64.4 0.1 7.5e-18 63.8 0.1 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 EPE29561.1 - 0.023 14.0 0.1 0.08 12.3 0.1 1.8 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Cytochrom_C_2 PF01322.15 EPE29561.1 - 0.053 14.0 0.1 0.064 13.7 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C' Translin PF01997.11 EPE29561.1 - 0.057 13.0 0.0 0.071 12.7 0.0 1.0 1 0 0 1 1 1 0 Translin family DHC_N1 PF08385.7 EPE29561.1 - 0.07 11.5 0.0 0.084 11.2 0.0 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 PspA_IM30 PF04012.7 EPE29561.1 - 0.097 12.0 0.9 0.12 11.7 0.4 1.3 1 1 0 1 1 1 0 PspA/IM30 family Baculo_PEP_C PF04513.7 EPE29561.1 - 0.11 12.3 0.5 0.14 11.9 0.3 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Corona_S2 PF01601.11 EPE29561.1 - 0.13 10.3 0.2 0.13 10.3 0.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein zf-RING_2 PF13639.1 EPE29562.1 - 1.8e-09 37.2 7.7 1.2e-08 34.6 5.3 2.1 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPE29562.1 - 9.7e-09 35.2 0.4 1.8e-08 34.3 0.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPE29562.1 - 6.1e-07 28.9 0.6 1e-06 28.3 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE29562.1 - 1.2e-06 28.1 0.6 2.5e-06 27.0 0.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE29562.1 - 1.9e-06 27.4 3.5 6e-06 25.8 2.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE29562.1 - 1.5e-05 24.9 6.1 2.9e-05 23.9 1.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.3 EPE29562.1 - 0.0099 13.6 0.2 0.014 13.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) zf-Apc11 PF12861.2 EPE29562.1 - 0.03 14.1 1.9 0.069 12.9 1.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EPE29562.1 - 0.11 12.0 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EPE29562.1 - 2.5 7.8 8.0 0.092 12.4 0.7 2.2 2 1 1 3 3 3 0 RING-type zinc-finger FANCL_C PF11793.3 EPE29562.1 - 3.7 7.5 6.1 22 5.1 4.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain DNA_ligase_A_M PF01068.16 EPE29563.1 - 9.7e-46 155.6 0.1 5e-45 153.3 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPE29563.1 - 6e-37 127.1 0.0 1.5e-36 125.8 0.0 1.6 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPE29563.1 - 7.3e-15 55.1 0.0 3.4e-14 53.0 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EPE29563.1 - 1.6e-05 24.9 0.0 0.00038 20.5 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain EF-hand_4 PF12763.2 EPE29566.1 - 0.047 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Peptidase_M28 PF04389.12 EPE29567.1 - 3e-21 75.9 0.1 5.5e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EPE29567.1 - 1.5e-05 24.5 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EPE29567.1 - 0.077 11.7 0.0 0.21 10.3 0.0 1.5 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase PTCB-BRCT PF12738.2 EPE29568.1 - 1.1e-46 156.4 0.1 8.8e-20 70.3 0.0 3.6 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 EPE29568.1 - 1.3e-30 105.3 0.2 3.3e-11 43.1 0.0 4.7 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain Fungal_trans PF04082.13 EPE29568.1 - 1.1e-14 53.9 0.2 2.1e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_20 PF00728.17 EPE29569.1 - 1.9e-83 280.5 0.0 2.4e-83 280.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EPE29569.1 - 5.3e-22 78.8 0.0 1.9e-21 77.0 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EPE29569.1 - 7.2e-06 26.5 0.1 0.00035 21.1 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.17 EPE29570.1 - 1.4e-67 228.1 0.0 1.8e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.16 EPE29571.1 - 7.1e-18 64.6 0.0 9.5e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EPE29571.1 - 0.00016 20.3 0.0 0.00041 19.0 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EPE29571.1 - 0.0024 16.9 0.0 0.033 13.2 0.0 2.2 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Amidase PF01425.16 EPE29572.1 - 1.8e-67 228.1 0.0 2.7e-67 227.5 0.0 1.3 1 1 0 1 1 1 1 Amidase DDE_Tnp_1_7 PF13843.1 EPE29572.1 - 0.094 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Transposase IS4 Glutaredoxin PF00462.19 EPE29572.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin CENP-K PF11802.3 EPE29573.1 - 1e-08 34.7 0.5 0.0063 15.7 0.0 2.1 2 0 0 2 2 2 2 Centromere-associated protein K WHEP-TRS PF00458.15 EPE29573.1 - 0.056 13.1 0.1 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 WHEP-TRS domain DASH_Dad3 PF08656.5 EPE29573.1 - 1.1 8.9 4.9 2.3 7.9 0.4 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad3 TarH PF02203.10 EPE29573.1 - 2.2 8.1 7.2 0.7 9.7 2.7 1.8 2 0 0 2 2 2 0 Tar ligand binding domain homologue FliT PF05400.8 EPE29573.1 - 5.6 7.4 19.9 5 7.6 1.7 3.4 3 0 0 3 3 3 0 Flagellar protein FliT CP12 PF02672.10 EPE29573.1 - 8.9 6.8 6.9 2.5 8.6 0.0 3.1 4 0 0 4 4 4 0 CP12 domain KH_1 PF00013.24 EPE29574.1 - 6.9e-38 128.1 4.1 2e-16 59.3 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EPE29574.1 - 8.3e-30 101.9 9.6 7.2e-12 44.6 1.7 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EPE29574.1 - 2.3e-13 49.4 3.3 0.0027 17.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EPE29574.1 - 3.8e-05 23.2 1.0 0.63 9.7 0.1 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EPE29574.1 - 0.011 15.5 6.7 0.44 10.3 0.1 3.2 3 0 0 3 3 3 0 NusA-like KH domain Recep_L_domain PF01030.19 EPE29576.1 - 0.0048 16.8 2.6 3.9 7.4 0.0 3.9 2 2 0 3 3 3 1 Receptor L domain Ecm33 PF12454.3 EPE29576.1 - 0.29 11.0 8.5 0.17 11.7 1.6 2.8 2 1 1 3 3 3 0 GPI-anchored cell wall organization protein ABM PF03992.11 EPE29577.1 - 3.1e-05 23.9 0.1 0.0017 18.3 0.0 2.6 2 1 1 3 3 3 2 Antibiotic biosynthesis monooxygenase MSC PF09402.5 EPE29578.1 - 1.6e-90 303.1 0.0 2.2e-90 302.7 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EPE29578.1 - 1.7e-16 59.4 0.0 3.4e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain DUF809 PF05663.6 EPE29578.1 - 1.9 8.3 5.0 5.3 6.9 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF809) HSP20 PF00011.16 EPE29579.1 - 6e-13 48.5 0.4 9.3e-13 47.9 0.2 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Peptidase_M20 PF01546.23 EPE29580.1 - 8.3e-24 84.1 0.2 1.4e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPE29580.1 - 1.3e-21 76.3 0.3 2.3e-21 75.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EPE29580.1 - 0.013 15.2 0.2 0.065 12.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase family M28 ACP_syn_III_C PF08541.5 EPE29580.1 - 0.11 12.5 0.2 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HAD PF12710.2 EPE29581.1 - 8.4e-09 35.8 0.0 1.3e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPE29581.1 - 7.7e-05 21.9 0.1 0.0021 17.2 0.0 2.3 2 0 0 2 2 2 1 Putative Phosphatase MutS_V PF00488.16 EPE29582.1 - 2.2e-81 272.6 0.0 3.6e-81 272.0 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPE29582.1 - 7.7e-39 133.5 0.2 1.9e-38 132.3 0.2 1.7 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EPE29582.1 - 2e-18 66.4 0.0 5.7e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EPE29582.1 - 5.7e-09 36.1 0.0 3.8e-08 33.4 0.0 2.3 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EPE29582.1 - 0.012 15.7 0.0 0.037 14.2 0.0 1.9 1 0 0 1 1 1 0 MutS family domain IV AAA_29 PF13555.1 EPE29582.1 - 0.027 14.0 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 EPE29582.1 - 0.13 11.9 0.2 19 4.9 0.0 3.3 2 1 0 2 2 2 0 NTPase Ribosomal_L10 PF00466.15 EPE29583.1 - 2.8e-25 88.1 0.1 6.9e-25 86.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EPE29583.1 - 8.4e-15 54.9 4.8 8.4e-15 54.9 3.3 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein WD40 PF00400.27 EPE29584.1 - 3e-05 23.7 0.2 0.17 11.8 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat CPSF_A PF03178.10 EPE29584.1 - 0.032 13.3 0.0 0.78 8.7 0.0 2.4 2 1 0 2 2 2 0 CPSF A subunit region 23S_rRNA_IVP PF05635.6 EPE29585.1 - 0.027 14.3 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein URO-D PF01208.12 EPE29586.1 - 1e-116 389.6 0.0 1.2e-116 389.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 EPE29586.1 - 0.057 13.0 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Phloem filament protein PP1 dCMP_cyt_deam_1 PF00383.17 EPE29587.1 - 1.9e-22 78.8 0.0 2.5e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EPE29587.1 - 0.0013 18.5 0.9 0.039 13.8 0.4 2.2 1 1 1 2 2 2 1 Bd3614-like deaminase XOO_2897-deam PF14440.1 EPE29587.1 - 0.0088 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.6 EPE29587.1 - 0.023 14.3 0.0 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 APOBEC-like N-terminal domain Oxysterol_BP PF01237.13 EPE29588.1 - 1.8e-55 187.8 0.0 2.2e-45 154.7 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein DUF2697 PF10906.3 EPE29589.1 - 0.001 19.0 0.1 0.0015 18.4 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2697) Y_phosphatase PF00102.22 EPE29590.1 - 1.1e-44 152.5 0.0 1.7e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EPE29590.1 - 0.0012 19.0 0.1 0.0069 16.6 0.0 2.2 1 1 1 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EPE29590.1 - 0.0078 16.2 0.0 0.025 14.6 0.0 2.0 1 1 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EPE29590.1 - 0.015 14.8 0.2 0.037 13.6 0.0 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Peptidase_M28 PF04389.12 EPE29591.1 - 1.3e-32 113.0 0.0 1.9e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EPE29591.1 - 7.3e-16 57.7 0.1 1.6e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 EPE29591.1 - 0.083 11.6 0.0 0.28 9.8 0.0 1.7 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase PhzC-PhzF PF02567.11 EPE29592.1 - 1e-37 129.8 0.6 1.1e-36 126.5 0.4 2.0 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Frag1 PF10277.4 EPE29593.1 - 6.7e-41 140.1 9.3 6.7e-41 140.1 6.4 2.8 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family P34-Arc PF04045.9 EPE29594.1 - 7.5e-101 336.4 0.3 9.1e-101 336.1 0.2 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EPE29594.1 - 0.02 14.2 0.2 0.038 13.3 0.1 1.4 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Radical_SAM PF04055.16 EPE29594.1 - 0.043 13.9 1.5 3.4 7.8 0.1 2.5 1 1 1 3 3 3 0 Radical SAM superfamily SF3b1 PF08920.5 EPE29596.1 - 1.9e-42 144.7 0.2 1.9e-42 144.7 0.1 2.1 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EPE29596.1 - 5.8e-14 52.1 2.3 0.011 16.0 0.0 7.3 6 2 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 EPE29596.1 - 3.5e-10 40.0 2.2 0.34 11.4 0.0 7.8 7 2 2 9 9 9 2 HEAT-like repeat HEAT PF02985.17 EPE29596.1 - 1.3e-09 37.3 9.5 1 9.6 0.0 9.2 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EPE29596.1 - 2.5e-05 24.5 0.2 0.91 9.9 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EPE29596.1 - 0.00038 18.9 0.1 0.19 9.9 0.0 3.0 2 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.7 EPE29596.1 - 0.014 14.7 0.2 12 5.2 0.0 3.9 4 0 0 4 4 4 0 NUC173 domain CLASP_N PF12348.3 EPE29596.1 - 0.039 13.3 0.1 0.92 8.8 0.0 3.0 3 0 0 3 3 3 0 CLASP N terminal DUF2945 PF11160.3 EPE29597.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2945) zf-H2C2_2 PF13465.1 EPE29598.1 - 4.5e-11 42.4 16.2 2.9e-06 27.2 1.1 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EPE29598.1 - 5.7e-09 35.7 15.0 2.1e-05 24.5 3.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE29598.1 - 1e-06 28.6 12.1 0.00022 21.3 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EPE29598.1 - 7.1e-06 26.0 1.5 2.1e-05 24.5 1.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPE29598.1 - 8.7e-05 22.5 5.1 0.00013 22.0 1.4 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EPE29598.1 - 0.00064 19.5 6.5 0.0043 16.9 1.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EPE29598.1 - 0.053 13.6 1.3 0.053 13.6 0.9 1.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 EPE29598.1 - 6.8 6.5 7.4 53 3.6 5.1 2.1 1 1 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.1 EPE29598.1 - 7.6 6.9 8.6 5.1 7.5 0.9 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain VRR_NUC PF08774.6 EPE29599.1 - 5.1e-18 64.9 0.0 2.3e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 VRR-NUC domain Dpy-30 PF05186.8 EPE29600.1 - 7.4e-14 50.9 0.0 1.2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.7 EPE29601.1 - 6.2e-30 102.8 0.0 1.2e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EPE29601.1 - 1.5e-22 79.1 0.0 2.5e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EPE29601.1 - 0.022 14.4 0.1 0.05 13.3 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain RRM_1 PF00076.17 EPE29602.1 - 1e-27 95.5 0.1 9.3e-12 44.4 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE29602.1 - 1.1e-21 76.5 0.0 7.5e-06 25.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE29602.1 - 2.1e-16 59.4 0.0 3.8e-07 29.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTV_NS2 PF04514.7 EPE29602.1 - 0.58 8.9 0.0 0.58 8.9 0.0 2.0 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 OGG_N PF07934.7 EPE29603.1 - 8.6e-28 96.6 1.6 1e-27 96.4 0.2 1.8 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EPE29603.1 - 3.3e-14 53.0 0.0 6.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EPE29603.1 - 0.00024 20.6 0.0 0.00058 19.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SNase PF00565.12 EPE29604.1 - 2.3e-22 79.2 0.7 3.8e-22 78.5 0.5 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Rax2 PF12768.2 EPE29605.1 - 1.4e-87 293.4 18.7 4.4e-81 272.1 0.0 6.0 4 2 1 6 6 6 6 Cortical protein marker for cell polarity zf-RING_2 PF13639.1 EPE29606.1 - 1.4e-08 34.4 5.1 2.3e-08 33.7 3.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPE29606.1 - 1.1e-06 28.5 2.0 2.2e-06 27.6 1.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPE29606.1 - 0.00052 19.7 1.9 0.001 18.8 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EPE29606.1 - 0.00058 19.4 2.5 0.0022 17.6 1.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE29606.1 - 0.0014 18.5 3.4 0.0035 17.3 2.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EPE29606.1 - 0.0044 16.9 1.4 0.75 9.8 0.0 2.5 2 0 0 2 2 2 1 zinc-finger zf-C3HC4_4 PF15227.1 EPE29606.1 - 0.0089 15.8 1.9 0.046 13.5 1.4 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EPE29606.1 - 0.0096 15.4 0.8 1.4 8.5 0.0 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.3 EPE29606.1 - 0.014 15.3 2.2 0.029 14.3 1.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Sgf11 PF08209.6 EPE29606.1 - 0.039 13.2 0.6 0.039 13.2 0.4 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Rad50_zn_hook PF04423.9 EPE29606.1 - 0.084 12.3 0.7 0.73 9.3 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_5 PF14634.1 EPE29606.1 - 1.3 8.7 4.8 39 4.0 0.2 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE29606.1 - 8.2 6.1 7.2 41 3.9 5.0 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) 7tm_2 PF00002.19 EPE29607.1 - 6.9e-07 28.5 6.3 6.9e-07 28.5 4.4 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (Secretin family) O-FucT PF10250.4 EPE29609.1 - 5.5e-05 22.4 0.0 0.00014 21.1 0.0 1.6 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase VSP PF03302.8 EPE29610.1 - 0.00035 19.3 1.4 0.00035 19.3 1.0 1.9 2 0 0 2 2 2 1 Giardia variant-specific surface protein PepSY_TM_2 PF13703.1 EPE29610.1 - 0.91 9.7 4.7 0.47 10.6 0.2 2.7 4 0 0 4 4 4 0 PepSY-associated TM helix NTF2 PF02136.15 EPE29611.1 - 2.1e-07 31.3 0.0 1.6e-06 28.4 0.0 2.7 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain TAP_C PF03943.8 EPE29611.1 - 1.6e-06 27.4 0.0 2.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EPE29611.1 - 1.3e-05 24.6 5.3 0.0075 15.8 0.0 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) COPIIcoated_ERV PF07970.7 EPE29612.1 - 2e-71 240.1 0.1 4.8e-69 232.3 0.0 2.3 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EPE29612.1 - 5e-34 116.1 0.0 1.3e-33 114.8 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sel1 PF08238.7 EPE29613.1 - 3.8e-14 52.7 7.7 0.0017 18.9 0.1 4.4 4 0 0 4 4 4 3 Sel1 repeat Dynamin_N PF00350.18 EPE29614.1 - 3e-13 49.9 0.0 3e-13 49.9 0.0 4.7 2 2 1 3 3 1 1 Dynamin family MMR_HSR1 PF01926.18 EPE29614.1 - 5.8e-07 29.4 0.4 1.9e-05 24.5 0.3 3.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EPE29614.1 - 0.00076 19.7 0.0 0.00076 19.7 0.0 3.5 3 1 0 3 3 2 1 ABC transporter DUF258 PF03193.11 EPE29614.1 - 0.0018 17.4 0.0 0.0095 15.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 EPE29614.1 - 0.0031 16.5 0.0 0.0031 16.5 0.0 3.0 3 0 0 3 3 3 1 KAP family P-loop domain Miro PF08477.8 EPE29614.1 - 0.0047 17.4 0.6 0.025 15.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein Adeno_IVa2 PF02456.10 EPE29614.1 - 0.022 13.4 0.0 0.044 12.4 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_22 PF13401.1 EPE29614.1 - 0.042 13.9 0.6 0.45 10.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EPE29614.1 - 0.045 14.5 0.0 0.045 14.5 0.0 4.0 3 1 0 3 3 2 0 AAA domain AAA_16 PF13191.1 EPE29614.1 - 0.12 12.3 0.1 0.12 12.3 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.1 EPE29614.1 - 0.15 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EPE29614.1 - 2.5 7.9 0.0 2.5 7.9 0.0 3.9 4 0 0 4 4 4 0 AAA domain RabGAP-TBC PF00566.13 EPE29616.1 - 3.5e-31 108.3 0.0 7.5e-26 90.9 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Sulfate_transp PF00916.15 EPE29617.1 - 4e-74 249.1 11.4 6.7e-74 248.3 7.9 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EPE29617.1 - 1.9e-31 107.5 5.2 1.9e-31 107.5 3.6 3.8 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EPE29617.1 - 2.2e-10 39.9 0.0 4.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain FTCD PF02971.9 EPE29617.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase domain RRN3 PF05327.6 EPE29619.1 - 1.2e-183 611.3 0.1 1.2e-183 611.3 0.1 1.5 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF3993 PF13158.1 EPE29619.1 - 0.021 14.6 0.3 0.052 13.3 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3993) Retrotrans_gag PF03732.12 EPE29619.1 - 0.042 13.9 0.2 8.1 6.5 0.0 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein CBFD_NFYB_HMF PF00808.18 EPE29620.1 - 3.6e-26 91.0 1.2 6.3e-26 90.2 0.8 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPE29620.1 - 5.3e-07 29.6 0.1 9.2e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EPE29620.1 - 0.0011 18.6 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EPE29620.1 - 0.0022 17.6 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EPE29620.1 - 0.091 13.0 0.1 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Abhydrolase_6 PF12697.2 EPE29621.1 - 2.8e-22 79.7 0.0 3.2e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE29621.1 - 3.7e-11 42.9 0.1 5.4e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPE29621.1 - 0.0067 16.0 0.1 0.13 11.7 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 EPE29621.1 - 0.053 13.0 0.1 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 EPE29621.1 - 0.1 11.8 0.0 12 5.1 0.0 2.6 2 1 1 3 3 3 0 Dienelactone hydrolase family Prefoldin_2 PF01920.15 EPE29622.1 - 5e-24 84.1 6.5 6.1e-24 83.8 4.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit FTA4 PF13093.1 EPE29622.1 - 0.0044 16.4 2.9 0.0049 16.3 2.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Prefoldin PF02996.12 EPE29622.1 - 0.01 15.4 6.6 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit GrpE PF01025.14 EPE29622.1 - 0.038 13.5 5.1 1.5 8.3 0.1 2.0 2 0 0 2 2 2 0 GrpE DASH_Dad3 PF08656.5 EPE29622.1 - 0.042 13.5 3.4 0.057 13.1 0.7 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4461 PF14688.1 EPE29622.1 - 0.068 12.4 1.6 0.079 12.2 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) UBN2 PF14223.1 EPE29622.1 - 0.092 12.5 5.5 2.4 7.9 1.0 2.7 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type DUF2316 PF10078.4 EPE29622.1 - 0.1 12.6 2.9 1.2 9.2 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Mnd1 PF03962.10 EPE29622.1 - 0.11 12.1 4.5 0.19 11.4 3.1 1.4 1 1 0 1 1 1 0 Mnd1 family Sec8_exocyst PF04048.9 EPE29622.1 - 0.13 11.8 2.7 0.17 11.5 0.3 1.9 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain GAS PF13851.1 EPE29622.1 - 0.17 11.0 8.6 0.44 9.6 6.0 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2205 PF10224.4 EPE29622.1 - 0.22 11.1 9.6 1.1 8.8 1.9 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF641 PF04859.7 EPE29622.1 - 0.24 11.1 4.0 0.71 9.6 0.2 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) WXG100 PF06013.7 EPE29622.1 - 0.27 11.2 4.5 0.99 9.4 2.2 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG V_ATPase_I PF01496.14 EPE29622.1 - 0.32 8.8 2.3 0.34 8.7 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrcA PF01628.16 EPE29622.1 - 0.48 9.9 3.3 2 7.9 2.3 1.9 1 1 0 1 1 1 0 HrcA protein C terminal domain Seryl_tRNA_N PF02403.17 EPE29622.1 - 0.49 10.4 4.8 2 8.4 0.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.6 EPE29622.1 - 0.57 10.6 3.9 3.7 8.0 0.9 2.1 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF1657 PF07870.6 EPE29622.1 - 0.67 9.6 4.6 2.6 7.7 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) Tho2 PF11262.3 EPE29622.1 - 0.69 8.9 3.8 7.2 5.5 0.9 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Muted PF14942.1 EPE29622.1 - 0.96 9.3 5.9 5.9 6.7 1.3 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Apolipoprotein PF01442.13 EPE29622.1 - 1 8.8 8.4 6.8 6.1 5.0 1.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF148 PF02520.12 EPE29622.1 - 1.2 8.9 8.2 6.1 6.6 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 Viral_P18 PF04521.8 EPE29622.1 - 2.2 7.7 5.2 15 5.0 1.2 2.1 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein IncA PF04156.9 EPE29622.1 - 4.7 6.7 8.9 7.7 6.0 6.2 1.6 1 1 0 1 1 1 0 IncA protein DUF4337 PF14235.1 EPE29622.1 - 5.5 6.8 7.2 1.2 8.9 2.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Tmemb_14 PF03647.8 EPE29623.1 - 2e-23 82.5 6.9 2.3e-23 82.4 4.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 EPE29623.1 - 0.0064 16.7 1.4 0.01 16.0 0.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) DAD PF02109.11 EPE29624.1 - 2e-48 163.1 2.4 2.6e-48 162.7 1.7 1.1 1 0 0 1 1 1 1 DAD family DUF4389 PF14333.1 EPE29624.1 - 0.03 14.0 0.6 0.05 13.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) GRASP55_65 PF04495.9 EPE29625.1 - 1.2e-46 158.1 0.0 3.7e-45 153.3 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Methyltransf_15 PF09445.5 EPE29626.1 - 3.2e-46 156.8 0.0 4.1e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EPE29626.1 - 7.7e-11 41.8 0.0 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EPE29626.1 - 1.7e-06 28.0 0.0 3.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EPE29626.1 - 3.2e-06 26.6 0.0 6.9e-06 25.5 0.0 1.5 1 1 1 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EPE29626.1 - 7.9e-06 26.4 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EPE29626.1 - 4.3e-05 23.2 0.0 5.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.15 EPE29626.1 - 5.5e-05 22.3 0.0 7.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EPE29626.1 - 0.003 16.9 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EPE29626.1 - 0.0068 16.0 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EPE29626.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Nucleoporin2 PF04096.9 EPE29627.1 - 0.025 14.4 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin autopeptidase HsdM_N PF12161.3 EPE29627.1 - 0.054 13.9 0.0 0.083 13.3 0.0 1.2 1 0 0 1 1 1 0 HsdM N-terminal domain Dopey_N PF04118.9 EPE29628.1 - 7.8e-122 405.8 0.0 5.1e-120 399.9 0.0 2.9 2 1 0 2 2 2 2 Dopey, N-terminal Mon1 PF03164.9 EPE29629.1 - 9.9e-116 386.7 0.0 1.2e-115 386.4 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Thioredoxin PF00085.15 EPE29631.1 - 5.5e-65 215.5 3.6 2.6e-33 113.7 0.1 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EPE29631.1 - 2.8e-51 173.9 2.7 8.3e-38 130.0 0.2 3.5 3 1 1 4 4 4 3 Thioredoxin-like domain Calsequestrin PF01216.12 EPE29631.1 - 1.5e-12 47.0 1.3 3.1e-12 45.9 0.5 1.8 2 1 0 2 2 2 1 Calsequestrin Thioredoxin_7 PF13899.1 EPE29631.1 - 2.2e-12 46.8 0.0 1.1e-05 25.3 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EPE29631.1 - 1.8e-10 41.0 3.2 5.3e-05 23.3 0.1 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPE29631.1 - 2.4e-10 40.4 0.2 0.0014 18.7 0.0 5.1 4 2 1 5 5 5 2 Thioredoxin-like Redoxin PF08534.5 EPE29631.1 - 8.6e-07 28.6 1.2 0.25 10.8 0.0 3.5 3 0 0 3 3 3 2 Redoxin AhpC-TSA PF00578.16 EPE29631.1 - 1.1e-06 28.3 0.5 0.0011 18.7 0.0 3.0 2 1 1 3 3 3 2 AhpC/TSA family KfrA_N PF11740.3 EPE29631.1 - 0.032 14.6 8.0 0.075 13.4 5.5 1.6 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Thioredoxin_3 PF13192.1 EPE29631.1 - 0.032 14.0 1.8 0.085 12.6 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain DUF883 PF05957.8 EPE29631.1 - 0.17 12.3 4.7 0.54 10.6 3.2 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Thioredoxin_4 PF13462.1 EPE29631.1 - 0.31 11.0 10.8 6.4 6.7 2.7 3.9 3 1 0 3 3 3 0 Thioredoxin IncA PF04156.9 EPE29632.1 - 0.054 13.0 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 IncA protein zf-HIT PF04438.11 EPE29633.1 - 2.6e-08 33.3 9.5 3.9e-08 32.7 6.6 1.3 1 0 0 1 1 1 1 HIT zinc finger Peptidase_M15 PF01427.12 EPE29633.1 - 0.12 11.9 0.1 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase Kelch_3 PF13415.1 EPE29634.1 - 2.4e-29 100.7 14.6 1.6e-10 40.8 0.0 6.9 7 0 0 7 7 7 3 Galactose oxidase, central domain DUF4110 PF13422.1 EPE29634.1 - 5.9e-26 90.1 0.3 5.9e-26 90.1 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 EPE29634.1 - 9.5e-22 76.5 19.6 8e-08 31.9 0.0 6.2 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EPE29634.1 - 9.9e-19 66.8 4.9 8e-08 32.0 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EPE29634.1 - 4.8e-16 58.1 5.9 0.00053 20.0 0.1 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EPE29634.1 - 6.4e-14 51.0 4.6 0.0068 16.1 0.0 6.1 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EPE29634.1 - 2.3e-11 43.0 12.1 1.8e-07 30.5 0.1 5.4 7 0 0 7 7 7 3 Kelch motif Abhydrolase_1 PF00561.15 EPE29635.1 - 6.5e-08 32.4 0.0 9.1e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE29635.1 - 6.3e-07 29.5 0.0 1.8e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE29635.1 - 2.6e-06 27.2 0.0 4e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE29635.1 - 0.023 13.9 0.0 0.056 12.6 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family FAD_binding_3 PF01494.14 EPE29636.1 - 1e-12 47.8 1.0 3.1e-11 42.9 0.2 2.6 2 1 0 2 2 2 1 FAD binding domain SE PF08491.5 EPE29636.1 - 0.00017 20.5 0.0 0.0059 15.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 EPE29636.1 - 0.074 11.9 1.8 0.17 10.7 0.7 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Methyltransf_2 PF00891.13 EPE29636.1 - 0.082 12.0 0.2 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 O-methyltransferase NAD_binding_8 PF13450.1 EPE29636.1 - 0.27 11.2 1.5 0.68 9.9 1.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain WLM PF08325.5 EPE29637.1 - 2.3e-49 167.8 0.0 4.6e-49 166.8 0.0 1.5 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EPE29637.1 - 4.2e-10 39.7 0.1 8.2e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 DZR PF12773.2 EPE29637.1 - 1.3 8.8 6.1 3.2 7.6 4.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon DUF605 PF04652.11 EPE29637.1 - 4.6 6.5 10.7 6 6.1 7.4 1.1 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 EPE29638.1 - 1.3e-48 165.4 0.0 2e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29638.1 - 1.7e-35 122.3 0.0 2.8e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE29638.1 - 0.024 13.6 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EPE29638.1 - 0.18 11.5 0.0 0.18 11.5 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EPE29638.1 - 0.25 10.3 2.6 0.25 10.3 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Telomere_reg-2 PF10193.4 EPE29639.1 - 2.9e-36 124.1 0.0 2.2e-35 121.3 0.0 2.5 2 0 0 2 2 2 1 Telomere length regulation protein ThiF PF00899.16 EPE29640.1 - 5.5e-37 126.6 0.1 1.6e-36 125.1 0.0 1.7 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EPE29640.1 - 2.5e-30 104.0 0.0 5.2e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EPE29640.1 - 6e-24 83.3 1.0 1.4e-23 82.1 0.7 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EPE29640.1 - 3.3e-15 55.1 2.5 3.3e-15 55.1 1.8 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Ecm33 PF12454.3 EPE29640.1 - 0.082 12.7 2.9 0.16 11.8 2.0 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Shikimate_DH PF01488.15 EPE29640.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RNA_pol_A_bac PF01000.21 EPE29641.1 - 4.6e-25 87.9 0.0 1.3e-24 86.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EPE29641.1 - 1.1e-11 43.6 0.0 2e-11 42.8 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain BBS1 PF14779.1 EPE29641.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Complex1_49kDa PF00346.14 EPE29642.1 - 7.8e-134 444.8 0.0 1e-133 444.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit F_actin_cap_B PF01115.12 EPE29645.1 - 7.4e-107 356.0 0.0 8.6e-107 355.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.12 EPE29645.1 - 0.078 12.0 0.0 0.19 10.7 0.0 1.6 1 1 0 1 1 1 0 F-actin capping protein alpha subunit Amino_oxidase PF01593.19 EPE29646.1 - 1.5e-85 287.9 0.0 2.9e-85 287.0 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EPE29646.1 - 4e-09 36.4 0.0 7.8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.14 EPE29646.1 - 6e-08 32.8 5.7 6e-08 32.8 4.0 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPE29646.1 - 2.7e-07 30.8 10.0 5.7e-07 29.8 7.0 1.6 1 0 0 1 1 1 1 HMG-box domain NAD_binding_8 PF13450.1 EPE29646.1 - 1.3e-06 28.3 0.0 3.5e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE29646.1 - 0.022 13.6 0.2 1.8 7.3 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Sec1 PF00995.18 EPE29647.1 - 9.4e-125 417.4 0.0 2.6e-122 409.3 0.0 2.0 1 1 0 1 1 1 1 Sec1 family tRNA-synt_His PF13393.1 EPE29648.1 - 1.7e-39 135.7 0.0 4.2e-33 114.7 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EPE29648.1 - 5.5e-17 61.8 0.0 8.9e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPE29648.1 - 2.5e-12 46.5 0.0 5.5e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EPE29648.1 - 0.00019 20.3 0.3 0.0056 15.4 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) MOZART1 PF12554.3 EPE29648.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Pkinase PF00069.20 EPE29650.1 - 2e-71 240.2 0.0 2.5e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29650.1 - 4.5e-34 117.7 0.0 7.4e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE29650.1 - 3.2e-06 26.3 0.0 5.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EPE29650.1 - 0.00052 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EPE29650.1 - 0.0074 15.3 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 EPE29651.1 - 9.2e-25 86.7 0.0 1.1e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPE29651.1 - 2.4e-06 27.3 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPE29651.1 - 4.7e-05 23.2 0.1 6.2e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EPE29651.1 - 0.031 13.9 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 UEV domain FAD_binding_3 PF01494.14 EPE29652.1 - 8.7e-25 87.5 0.0 1.7e-23 83.2 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE29652.1 - 5.4e-06 25.5 0.0 0.0042 16.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE29652.1 - 0.0004 19.4 0.1 0.047 12.5 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein SE PF08491.5 EPE29652.1 - 0.0028 16.5 0.0 0.0042 15.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 EPE29652.1 - 0.0088 15.9 0.0 0.023 14.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPE29652.1 - 0.018 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPE29652.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EPE29652.1 - 0.026 13.0 0.0 0.2 10.1 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 EPE29652.1 - 0.058 12.0 0.0 1.1 7.8 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 EPE29652.1 - 0.074 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Topoisom_I_N PF02919.10 EPE29653.1 - 2.4e-97 324.4 3.9 2.4e-97 324.4 2.7 3.7 4 2 1 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EPE29653.1 - 1.7e-85 285.8 8.6 1.7e-85 285.8 6.0 2.5 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EPE29653.1 - 5.7e-31 105.9 0.2 2.4e-30 103.9 0.1 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-synt PF00231.14 EPE29654.1 - 3.7e-69 233.2 3.4 4.2e-69 233.1 2.4 1.0 1 0 0 1 1 1 1 ATP synthase Beta-Casp PF10996.3 EPE29654.1 - 0.0033 17.3 0.0 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Ribosomal_S3_C PF00189.15 EPE29654.1 - 0.037 14.2 0.1 0.084 13.0 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain Epimerase PF01370.16 EPE29656.1 - 9e-20 71.1 0.0 1.2e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPE29656.1 - 2.9e-12 46.0 0.0 4.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPE29656.1 - 6.2e-06 26.3 0.2 0.00025 21.0 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EPE29656.1 - 7.8e-06 25.9 0.0 0.00027 20.8 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EPE29656.1 - 0.00074 18.3 0.0 0.0012 17.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EPE29656.1 - 0.048 13.3 0.0 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 KR domain Saccharop_dh PF03435.13 EPE29656.1 - 0.12 11.2 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DLH PF01738.13 EPE29658.1 - 2e-22 79.5 0.2 4e-11 42.6 0.0 3.0 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPE29658.1 - 6.6e-07 29.1 0.0 1.3e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE29658.1 - 0.0039 16.4 0.0 0.023 13.9 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EPE29658.1 - 0.0095 15.8 0.2 1.5 8.6 0.0 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family BTB PF00651.26 EPE29659.1 - 0.0072 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3425 PF11905.3 EPE29659.1 - 0.095 12.5 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) Med14 PF08638.6 EPE29660.1 - 7.6e-71 237.4 0.1 1.4e-70 236.5 0.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG22 PF11700.3 EPE29661.1 - 1.5e-204 679.9 12.9 1.7e-204 679.7 9.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EPE29661.1 - 5.4e-06 25.3 6.5 5.4e-06 25.3 4.5 3.4 2 2 1 3 3 3 2 Major Facilitator Superfamily UBN2_3 PF14244.1 EPE29662.1 - 0.00019 21.0 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type RTC4 PF14474.1 EPE29664.1 - 1.6e-28 99.1 0.0 3.1e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain Dynamitin PF04912.9 EPE29665.1 - 1.2e-32 113.1 2.9 4e-16 58.8 0.0 3.3 2 1 0 2 2 2 2 Dynamitin Laminin_II PF06009.7 EPE29665.1 - 0.0014 18.4 0.9 0.27 10.9 0.1 3.5 3 1 1 4 4 4 1 Laminin Domain II Sipho_Gp157 PF05565.6 EPE29665.1 - 0.048 13.2 1.0 7.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 Cwf_Cwc_15 PF04889.7 EPE29665.1 - 0.22 11.1 11.0 0.046 13.4 3.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein bZIP_Maf PF03131.12 EPE29665.1 - 0.63 10.3 6.9 1.1 9.5 2.0 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor DivIC PF04977.10 EPE29665.1 - 0.66 9.5 5.5 7.6 6.1 0.1 3.2 3 0 0 3 3 3 0 Septum formation initiator MFS_2 PF13347.1 EPE29666.1 - 1.6e-12 46.5 12.4 1.6e-12 46.5 8.6 2.2 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 EPE29666.1 - 0.00095 18.9 0.9 0.024 14.4 0.0 3.2 2 0 0 2 2 2 1 MFS_1 like family DUF962 PF06127.6 EPE29666.1 - 0.0076 16.1 1.0 2.4 8.1 0.0 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF962) UCH PF00443.24 EPE29667.1 - 1.3e-62 211.3 0.0 2.2e-62 210.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPE29667.1 - 6.1e-30 104.6 0.7 1.7e-22 80.2 0.2 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EPE29667.1 - 0.014 14.6 4.1 0.2 10.9 0.8 2.5 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase UIM PF02809.15 EPE29667.1 - 0.022 14.3 0.3 0.051 13.1 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Borrelia_P83 PF05262.6 EPE29667.1 - 1.4 7.0 18.0 2.1 6.5 12.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Yos1 PF08571.5 EPE29668.1 - 1.3e-12 47.6 0.0 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.12 EPE29669.1 - 1.6e-41 142.7 13.7 2.1e-41 142.3 9.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HflK_N PF12221.3 EPE29670.1 - 0.032 13.9 0.0 0.094 12.4 0.0 1.8 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Integrin_b_cyt PF08725.6 EPE29670.1 - 0.056 12.8 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain adh_short PF00106.20 EPE29672.1 - 6.9e-15 55.3 0.2 1.1e-14 54.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE29672.1 - 4.2e-07 29.8 0.8 7e-07 29.0 0.6 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPE29672.1 - 0.019 13.8 0.1 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Alpha-amylase PF00128.19 EPE29672.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain SNF2_N PF00176.18 EPE29673.1 - 6.9e-58 195.8 0.0 9.4e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE29673.1 - 1.9e-13 50.0 0.2 5.2e-13 48.6 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE29673.1 - 2.3e-06 27.5 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPE29673.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EPE29673.1 - 0.0013 17.6 0.0 0.003 16.4 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 UBA PF00627.26 EPE29673.1 - 0.015 15.1 0.1 0.045 13.6 0.0 1.9 1 0 0 1 1 1 0 UBA/TS-N domain VMA21 PF09446.5 EPE29674.1 - 1.9e-16 59.6 5.0 2.7e-16 59.2 3.5 1.2 1 0 0 1 1 1 1 VMA21-like domain Toprim_3 PF13362.1 EPE29674.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Toprim domain DUF2406 PF10295.4 EPE29675.1 - 4.6e-19 68.6 0.5 1.4e-18 67.1 0.4 1.9 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Ribosomal_L35Ae PF01247.13 EPE29676.1 - 5.8e-44 147.7 0.7 6.5e-44 147.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EPE29676.1 - 0.0021 17.9 0.0 0.84 9.6 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain G6PD_C PF02781.11 EPE29677.1 - 7e-120 399.3 0.0 3.1e-119 397.1 0.0 1.9 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EPE29677.1 - 2.1e-66 223.6 0.2 3.1e-66 223.0 0.2 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.3 EPE29677.1 - 0.00058 19.3 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) DLH PF01738.13 EPE29678.1 - 2.8e-07 30.0 0.0 3.5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family PRiA4_ORF3 PF07929.6 EPE29679.1 - 6.2e-15 55.0 0.0 7.7e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.13 EPE29679.1 - 2.6e-10 39.9 9.0 5.4e-10 38.9 6.3 1.6 1 0 0 1 1 1 1 MYND finger HARP PF07443.8 EPE29679.1 - 0.081 12.3 0.4 0.19 11.1 0.3 1.6 1 0 0 1 1 1 0 HepA-related protein (HARP) DUF1029 PF06269.7 EPE29681.1 - 0.1 12.6 2.0 0.17 11.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1029) K_trans PF02705.11 EPE29681.1 - 0.18 10.1 0.5 0.24 9.7 0.3 1.0 1 0 0 1 1 1 0 K+ potassium transporter BAH PF01426.13 EPE29682.1 - 2.9e-05 23.7 0.0 6.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 BAH domain FANCL_C PF11793.3 EPE29682.1 - 0.0025 17.7 2.0 0.0025 17.7 1.4 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.24 EPE29682.1 - 0.43 10.3 12.0 0.058 13.0 3.3 2.3 2 0 0 2 2 2 0 PHD-finger DUF3602 PF12223.3 EPE29683.1 - 8.9e-12 45.2 15.1 9.2e-10 38.7 3.6 2.7 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Mito_carr PF00153.22 EPE29684.1 - 1.7e-50 168.6 10.1 6.4e-19 67.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.23 EPE29685.1 - 1.6e-05 24.5 0.0 0.082 12.7 0.0 3.1 1 1 1 2 2 2 2 CBS domain Phage_Gp23 PF10669.4 EPE29686.1 - 0.0045 17.0 0.4 0.0095 16.0 0.3 1.5 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) DUF3015 PF11220.3 EPE29686.1 - 0.1 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DUF479 PF04336.7 EPE29686.1 - 0.12 12.4 0.5 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF479 PdxJ PF03740.8 EPE29687.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ Glyco_hydro_16 PF00722.16 EPE29688.1 - 2.7e-39 134.3 2.2 4.8e-39 133.5 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PP2C PF00481.16 EPE29689.1 - 1.3e-53 182.0 0.0 2.2e-53 181.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EPE29689.1 - 8.2e-42 140.2 59.7 5.3e-06 25.9 1.9 12.7 7 3 5 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE29689.1 - 1.1e-37 127.5 48.1 2.2e-09 36.9 1.2 10.1 5 3 6 11 11 11 10 Leucine rich repeat Guanylate_cyc PF00211.15 EPE29689.1 - 1.3e-25 89.8 0.0 3.2e-25 88.5 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EPE29689.1 - 5.5e-22 74.4 49.8 0.035 14.1 0.0 17.6 19 0 0 19 19 19 9 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 EPE29689.1 - 7.3e-12 44.4 0.5 7.3e-12 44.4 0.4 2.2 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain RA PF00788.18 EPE29689.1 - 4.4e-10 39.9 0.0 1.8e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 EPE29689.1 - 3.5e-07 29.3 55.4 0.51 10.7 0.1 15.9 18 0 0 18 18 18 3 Leucine rich repeat LRR_9 PF14580.1 EPE29689.1 - 0.021 14.4 10.1 0.19 11.3 0.2 4.1 2 1 2 4 4 4 0 Leucine-rich repeat LRR_6 PF13516.1 EPE29689.1 - 1.6 9.0 51.4 9.1 6.6 0.3 14.5 15 2 2 17 17 17 0 Leucine Rich repeat Arrestin_C PF02752.17 EPE29690.1 - 1.4e-20 73.7 0.0 4.6e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EPE29690.1 - 1.8e-08 34.3 0.1 0.003 17.4 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain zf-CCCH_2 PF14608.1 EPE29691.1 - 1.4e-13 50.2 45.4 7.6e-06 25.7 4.4 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EPE29691.1 - 0.023 14.7 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Amino_oxidase PF01593.19 EPE29692.1 - 1.7e-17 63.6 0.0 2.9e-17 62.8 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPE29692.1 - 1.6e-13 50.4 0.1 3.1e-12 46.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE29692.1 - 1.1e-06 27.7 0.0 5.8e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPE29692.1 - 0.021 15.2 0.1 0.079 13.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE29692.1 - 0.11 11.6 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Peptidase_C39 PF03412.10 EPE29693.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family IBR PF01485.16 EPE29694.1 - 5.2e-10 39.0 3.2 5.2e-10 39.0 2.2 3.0 2 1 0 2 2 2 1 IBR domain Phosducin PF02114.11 EPE29695.1 - 1.4e-12 46.9 2.4 5.2e-12 45.0 0.1 2.3 2 1 0 2 2 2 1 Phosducin IBR PF01485.16 EPE29696.1 - 2.7e-19 68.7 17.7 1.9e-11 43.6 1.0 4.0 3 1 1 4 4 4 2 IBR domain NAD_binding_8 PF13450.1 EPE29697.1 - 2.2e-12 46.8 0.2 2.8e-11 43.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE29697.1 - 2.2e-08 34.2 0.0 4.6e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE29697.1 - 1.1e-07 31.1 1.0 2.6e-07 29.8 0.7 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EPE29697.1 - 1.4e-07 31.8 0.3 0.0028 18.0 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE29697.1 - 2.3e-07 30.0 0.4 7.2e-06 25.1 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPE29697.1 - 3.1e-06 26.4 0.2 6.5e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EPE29697.1 - 2.6e-05 22.8 1.0 0.00022 19.8 0.6 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EPE29697.1 - 0.00014 21.1 0.2 0.00086 18.4 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPE29697.1 - 0.00016 21.7 0.1 0.0007 19.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE29697.1 - 0.00033 20.4 0.0 0.0033 17.2 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EPE29697.1 - 0.0012 17.9 0.2 0.002 17.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EPE29697.1 - 0.003 16.6 0.1 0.018 14.1 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 EPE29697.1 - 0.021 13.4 0.5 0.04 12.5 0.3 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Shikimate_DH PF01488.15 EPE29697.1 - 0.035 14.2 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EPE29697.1 - 0.065 12.0 0.7 0.11 11.2 0.5 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EPE29697.1 - 0.12 11.9 0.2 0.36 10.3 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Abi PF02517.11 EPE29698.1 - 4.7e-15 55.4 13.6 6.9e-15 54.9 8.3 2.3 1 1 0 1 1 1 1 CAAX protease self-immunity UPF0233 PF06781.7 EPE29698.1 - 0.23 11.1 2.5 5.8 6.6 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Synaptobrevin PF00957.16 EPE29700.1 - 0.014 14.9 0.2 0.014 14.9 0.1 2.0 2 0 0 2 2 2 0 Synaptobrevin MBOAT PF03062.14 EPE29701.1 - 3e-50 171.1 3.9 3e-50 171.1 2.7 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Sec1 PF00995.18 EPE29702.1 - 5.2e-155 517.2 0.1 6e-155 517.0 0.1 1.0 1 0 0 1 1 1 1 Sec1 family HEAT_2 PF13646.1 EPE29702.1 - 0.022 15.0 0.3 0.34 11.2 0.1 2.6 3 0 0 3 3 3 0 HEAT repeats Cellulase PF00150.13 EPE29703.1 - 1.3e-20 73.7 4.6 1.9e-20 73.2 3.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DER1 PF04511.10 EPE29704.1 - 3.5e-21 75.6 1.5 4.1e-21 75.4 1.0 1.0 1 0 0 1 1 1 1 Der1-like family Saccharop_dh PF03435.13 EPE29705.1 - 3e-131 437.9 0.0 3.5e-131 437.7 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EPE29705.1 - 7.4e-09 35.8 0.6 1.8e-06 28.1 0.1 2.2 2 0 0 2 2 2 2 NADH(P)-binding Shikimate_DH PF01488.15 EPE29705.1 - 4.1e-06 26.9 0.1 6.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EPE29705.1 - 0.00034 20.0 0.2 0.008 15.5 0.0 2.8 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EPE29705.1 - 0.0066 16.8 0.1 0.014 15.8 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pterin_bind PF00809.17 EPE29705.1 - 0.0097 15.2 0.3 0.27 10.5 0.2 2.2 1 1 0 1 1 1 1 Pterin binding enzyme TrkA_N PF02254.13 EPE29705.1 - 0.016 15.2 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.17 EPE29705.1 - 0.034 14.6 0.1 0.075 13.5 0.1 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3Beta_HSD PF01073.14 EPE29705.1 - 0.15 10.7 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CN_hydrolase PF00795.17 EPE29706.1 - 1.3e-12 47.5 0.0 2.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_61 PF03443.9 EPE29707.1 - 1.6e-64 217.7 0.2 2.2e-64 217.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ABC_tran PF00005.22 EPE29708.1 - 5.9e-38 130.2 0.0 1e-17 64.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPE29708.1 - 1.3e-23 83.8 25.2 2.5e-22 79.5 8.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EPE29708.1 - 1.5e-13 51.4 0.1 3.7e-05 23.8 0.0 4.4 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EPE29708.1 - 4.8e-12 45.5 1.5 0.00054 19.2 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPE29708.1 - 2.4e-08 33.3 0.2 0.0031 17.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EPE29708.1 - 3.3e-07 30.5 0.0 0.023 14.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPE29708.1 - 4.3e-07 30.1 0.0 0.0051 16.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 EPE29708.1 - 7.6e-07 28.2 0.0 0.00054 18.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 EPE29708.1 - 9.4e-07 29.6 0.0 0.041 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EPE29708.1 - 1.2e-05 25.2 0.2 0.23 11.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EPE29708.1 - 1.5e-05 25.3 0.0 0.064 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EPE29708.1 - 1.8e-05 24.3 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Dynamin_N PF00350.18 EPE29708.1 - 2.7e-05 24.0 0.1 0.026 14.3 0.0 2.5 2 0 0 2 2 2 2 Dynamin family DUF258 PF03193.11 EPE29708.1 - 3.8e-05 22.9 0.1 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EPE29708.1 - 6.3e-05 23.4 1.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EPE29708.1 - 7.9e-05 22.1 0.1 0.037 13.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EPE29708.1 - 0.00017 21.4 0.6 0.0084 15.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 EPE29708.1 - 0.00018 22.0 0.0 0.026 15.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 EPE29708.1 - 0.00024 20.9 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EPE29708.1 - 0.00029 20.6 1.4 1.1 9.2 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EPE29708.1 - 0.00039 20.6 0.0 1.5 9.0 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EPE29708.1 - 0.00048 19.8 0.4 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EPE29708.1 - 0.0015 17.9 2.0 0.34 10.3 0.2 2.6 3 0 0 3 3 2 1 AAA-like domain ATP_bind_1 PF03029.12 EPE29708.1 - 0.0022 17.5 0.1 0.041 13.4 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EPE29708.1 - 0.0087 16.2 0.1 3.8 7.7 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Adeno_IVa2 PF02456.10 EPE29708.1 - 0.015 14.0 0.1 3.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein IIGP PF05049.8 EPE29708.1 - 0.031 13.0 0.1 4.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Arch_ATPase PF01637.13 EPE29708.1 - 0.045 13.4 0.0 7.6 6.1 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 EPE29708.1 - 0.045 13.4 0.4 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain TrwB_AAD_bind PF10412.4 EPE29708.1 - 0.071 11.7 0.5 17 3.8 0.0 3.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.21 EPE29708.1 - 0.073 12.5 0.0 28 4.1 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_5 PF07728.9 EPE29708.1 - 0.13 11.9 0.2 26 4.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EPE29708.1 - 0.14 11.3 0.3 12 4.9 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EPE29708.1 - 0.25 10.3 0.0 13 4.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AIG1 PF04548.11 EPE29708.1 - 0.78 8.8 1.9 5.7 5.9 0.1 2.7 2 0 0 2 2 2 0 AIG1 family PepSY_TM_2 PF13703.1 EPE29709.1 - 0.095 12.8 0.2 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix TPR_12 PF13424.1 EPE29710.1 - 0.003 17.4 0.4 0.17 11.8 0.0 1.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPE29710.1 - 0.012 15.5 0.1 0.61 10.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Mid2 PF04478.7 EPE29711.1 - 0.0047 16.3 0.0 0.014 14.7 0.0 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.10 EPE29711.1 - 0.035 13.6 0.5 0.062 12.8 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rax2 PF12768.2 EPE29711.1 - 0.046 12.9 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.5 EPE29711.1 - 0.096 12.0 0.3 0.2 10.9 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RRM_6 PF14259.1 EPE29713.1 - 1.4e-05 24.9 0.1 0.00014 21.8 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 EPE29713.1 - 0.00063 19.9 23.8 0.02 15.2 1.0 5.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPE29713.1 - 0.0012 19.0 0.3 0.0012 19.0 0.2 3.5 5 0 0 5 5 5 1 Zinc-finger double domain RRM_5 PF13893.1 EPE29713.1 - 0.0027 17.5 0.0 0.007 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 EPE29713.1 - 0.027 14.5 2.5 0.43 10.7 0.0 3.7 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.17 EPE29713.1 - 0.028 14.0 0.0 0.072 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.1 EPE29713.1 - 0.032 14.5 20.5 0.71 10.3 1.1 5.0 3 1 0 3 3 3 0 C2H2-type zinc finger zf-CHCC PF10276.4 EPE29713.1 - 0.043 13.6 3.6 2.7 7.9 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger domain DKCLD PF08068.7 EPE29714.1 - 1.4e-28 98.5 0.1 9.4e-28 95.9 0.0 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EPE29714.1 - 3.8e-24 85.5 0.2 3.1e-21 76.0 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EPE29714.1 - 4.4e-21 74.3 1.1 8.6e-21 73.4 0.7 1.5 1 0 0 1 1 1 1 PUA domain RNase_H2-Ydr279 PF09468.5 EPE29714.1 - 1.1 8.4 7.5 1.6 7.8 5.2 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Med19 PF10278.4 EPE29714.1 - 2.4 7.8 12.4 3.4 7.2 8.0 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Spo12 PF05032.7 EPE29715.1 - 1.8e-13 49.8 2.4 3.5e-13 48.9 1.7 1.5 1 0 0 1 1 1 1 Spo12 family Nucleoporin_FG PF13634.1 EPE29715.1 - 0.032 14.4 3.2 0.038 14.2 2.2 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region Acyl-CoA_dh_1 PF00441.19 EPE29716.1 - 1.5e-29 103.0 0.2 3.2e-29 101.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPE29716.1 - 1.2e-15 56.7 0.0 2.6e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EPE29716.1 - 2.1e-14 53.9 0.4 4.7e-14 52.7 0.3 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EPE29716.1 - 1e-13 51.8 0.0 2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Toxin_14 PF07829.6 EPE29717.1 - 0.38 10.5 0.0 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 Alpha-A conotoxin PIVA-like protein MMR_HSR1 PF01926.18 EPE29718.1 - 5.3e-17 61.8 0.2 3.2e-15 56.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE29718.1 - 6.1e-07 28.8 0.1 1.6e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EPE29718.1 - 7.1e-05 22.0 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EPE29718.1 - 0.0055 15.8 0.1 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EPE29718.1 - 0.0071 16.1 4.8 0.025 14.4 0.1 3.1 3 0 0 3 3 3 1 Dynamin family Miro PF08477.8 EPE29718.1 - 0.032 14.7 1.0 0.07 13.6 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein TRAP_alpha PF03896.11 EPE29718.1 - 0.15 11.0 5.4 0.28 10.1 3.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Na_trans_assoc PF06512.8 EPE29718.1 - 0.27 11.1 10.4 0.61 10.0 7.2 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated LTV PF04180.9 EPE29719.1 - 3.2e-105 353.0 16.3 3.8e-105 352.8 11.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein SAC3_GANP PF03399.11 EPE29720.1 - 3.2e-43 147.6 0.4 5e-43 147.0 0.3 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TGS PF02824.16 EPE29721.1 - 1.7e-19 69.3 0.1 3.3e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EPE29721.1 - 8.1e-19 67.6 0.0 2.6e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE29721.1 - 3.9e-13 48.9 0.0 6.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPE29721.1 - 0.00031 20.6 0.2 0.9 9.3 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EPE29721.1 - 0.005 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EPE29721.1 - 0.056 12.2 0.1 0.13 11.0 0.1 1.5 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 EPE29721.1 - 0.095 11.4 0.0 0.19 10.4 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family Methyltransf_33 PF10017.4 EPE29721.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DNA_pol_B PF00136.16 EPE29722.1 - 3.2e-109 365.7 4.9 5e-109 365.1 3.4 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EPE29722.1 - 5.8e-63 211.6 4.4 1.1e-62 210.8 3.1 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EPE29722.1 - 2.3e-38 131.8 0.0 5.5e-38 130.6 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EPE29722.1 - 1.1e-20 73.2 16.8 2.5e-19 68.8 8.2 2.9 2 0 0 2 2 2 2 DNA polymerase alpha subunit p180 N terminal PPR_2 PF13041.1 EPE29723.1 - 2.9e-29 100.7 0.7 2.6e-17 62.5 0.0 2.8 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.15 EPE29723.1 - 2.6e-11 42.6 2.6 0.00049 19.9 0.1 4.8 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 EPE29723.1 - 5.7e-11 41.7 2.1 0.0093 16.1 0.0 5.8 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EPE29723.1 - 5.2e-09 35.4 0.6 0.32 10.4 0.0 4.5 4 0 0 4 4 4 4 PPR repeat RRM_1 PF00076.17 EPE29725.1 - 1.1e-06 28.1 0.0 1.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE29725.1 - 3.8e-05 23.5 0.0 0.00023 21.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE29725.1 - 6.9e-05 22.6 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIF4G PF02854.14 EPE29726.1 - 2e-52 177.6 0.0 2.9e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EPE29726.1 - 1.1e-21 76.4 0.7 4.6e-21 74.4 0.5 2.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 PCEMA1 PF07418.6 EPE29726.1 - 1.7 7.9 26.5 4.1 6.6 18.4 1.6 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Pkinase PF00069.20 EPE29727.1 - 8.2e-53 179.2 0.0 1.8e-52 178.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29727.1 - 1.3e-23 83.3 0.1 3e-23 82.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EPE29727.1 - 0.00025 20.8 0.1 0.00067 19.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPE29727.1 - 0.0039 16.5 0.2 0.012 15.0 0.2 1.7 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 EPE29727.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) SNF2_N PF00176.18 EPE29728.1 - 3.3e-69 232.9 0.0 6.6e-69 231.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE29728.1 - 2.1e-15 56.3 0.0 8e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EPE29728.1 - 9.4e-05 21.3 0.0 0.0003 19.6 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 LON PF02190.11 EPE29730.1 - 1.4e-28 99.9 0.0 2.2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_3 PF13920.1 EPE29730.1 - 3.9e-10 39.2 6.2 3.9e-10 39.2 4.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE29730.1 - 1.2e-08 34.6 11.6 3.5e-08 33.1 8.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE29730.1 - 1.4e-08 34.6 10.2 3.4e-08 33.3 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE29730.1 - 5.5e-07 29.1 8.8 5.5e-07 29.1 6.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE29730.1 - 6.1e-07 29.0 9.0 1.3e-06 27.9 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPE29730.1 - 1.2e-05 25.0 7.2 1.2e-05 25.0 5.0 2.8 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPE29730.1 - 6.6e-05 22.5 2.7 6.6e-05 22.5 1.9 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_4 PF14570.1 EPE29730.1 - 0.0014 18.1 6.4 0.0051 16.3 4.4 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EPE29730.1 - 0.0017 18.4 2.8 0.0046 17.0 1.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-P11 PF03854.9 EPE29730.1 - 0.0039 16.6 5.9 0.008 15.6 4.1 1.5 1 0 0 1 1 1 1 P-11 zinc finger U-box PF04564.10 EPE29730.1 - 0.087 12.7 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 U-box domain MTHFR_C PF12225.3 EPE29730.1 - 0.34 10.4 4.1 0.39 10.2 0.0 2.4 2 1 1 3 3 3 0 Methylene-tetrahydrofolate reductase C terminal 3HCDH_N PF02737.13 EPE29731.1 - 5.2e-52 176.1 1.0 6.7e-52 175.7 0.7 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EPE29731.1 - 7.2e-34 116.0 0.0 1.5e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EPE29731.1 - 4.7e-05 23.2 0.1 0.0001 22.1 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 EPE29731.1 - 0.00047 19.2 0.1 0.00066 18.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DAO PF01266.19 EPE29731.1 - 0.0053 15.7 0.4 0.0089 14.9 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EPE29731.1 - 0.014 15.1 0.3 0.027 14.2 0.2 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EPE29731.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EPE29731.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 EPE29731.1 - 0.02 15.2 0.1 0.081 13.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EPE29731.1 - 0.029 14.7 0.0 0.07 13.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.9 EPE29731.1 - 0.048 13.5 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UPF0137 PF03677.8 EPE29731.1 - 0.059 12.8 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Pyr_redox_3 PF13738.1 EPE29731.1 - 0.075 13.0 1.1 0.25 11.3 0.7 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EPE29731.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain TIMELESS PF04821.9 EPE29732.1 - 6e-95 317.4 0.0 1e-94 316.7 0.0 1.4 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 EPE29732.1 - 7e-35 120.9 23.4 7e-35 120.9 16.2 3.8 2 1 0 2 2 2 1 Timeless protein C terminal region Arg_repressor_C PF02863.13 EPE29732.1 - 0.075 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Acetyltransf_10 PF13673.1 EPE29733.1 - 0.00019 21.5 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE29733.1 - 0.0005 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 EPE29733.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EPE29733.1 - 0.053 13.6 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Homeobox PF00046.24 EPE29734.1 - 7.4e-17 60.7 4.5 9.3e-17 60.3 2.2 1.8 2 0 0 2 2 2 1 Homeobox domain Sigma70_ner PF04546.8 EPE29734.1 - 0.026 14.1 5.0 0.051 13.1 3.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Homeobox_KN PF05920.6 EPE29734.1 - 0.045 13.4 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain AAA_12 PF13087.1 EPE29735.1 - 6.7e-27 94.1 0.0 1.2e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPE29735.1 - 1.3e-22 80.5 0.0 2.9e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE29735.1 - 5.2e-09 35.7 0.0 3.1e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EPE29735.1 - 8.4e-05 22.2 0.0 0.011 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EPE29735.1 - 0.00033 20.5 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EPE29735.1 - 0.00062 19.2 0.0 0.0022 17.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.13 EPE29735.1 - 0.0014 18.2 0.1 0.062 12.8 0.0 2.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EPE29735.1 - 0.0014 18.8 0.0 0.005 17.0 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE29735.1 - 0.0033 17.5 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPE29735.1 - 0.0084 16.1 0.1 0.057 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 EPE29735.1 - 0.014 14.4 0.9 0.021 13.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 EPE29735.1 - 0.019 13.8 0.0 0.051 12.4 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.7 EPE29735.1 - 0.035 13.1 0.0 0.085 11.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 EPE29735.1 - 0.043 13.5 0.0 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EPE29735.1 - 0.045 12.6 0.0 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain UvrD_C_2 PF13538.1 EPE29735.1 - 0.046 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DEAD PF00270.24 EPE29735.1 - 0.046 13.2 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Parvo_NS1 PF01057.12 EPE29735.1 - 0.05 12.4 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 EPE29735.1 - 0.051 13.4 0.1 0.39 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EPE29735.1 - 0.064 14.0 0.0 0.84 10.4 0.0 3.0 2 0 0 2 2 1 0 AAA domain ATP-synt_ab PF00006.20 EPE29735.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EPE29735.1 - 0.23 11.6 0.0 0.61 10.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase efThoc1 PF11957.3 EPE29736.1 - 3.3e-154 514.0 2.4 3.3e-154 514.0 1.7 1.8 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 EPE29736.1 - 8.3e-48 162.2 0.2 8.3e-48 162.2 0.1 2.1 2 0 0 2 2 2 1 Guanylate kinase DUF258 PF03193.11 EPE29736.1 - 3.8e-07 29.4 0.0 8.6e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EPE29736.1 - 6.1e-06 26.5 0.1 6.1e-06 26.5 0.0 2.3 3 1 0 3 3 1 1 AAA domain MMR_HSR1 PF01926.18 EPE29736.1 - 3.6e-05 23.6 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPE29736.1 - 0.00018 22.0 0.6 0.0035 17.8 0.0 2.9 3 0 0 3 3 3 1 Miro-like protein ABC_tran PF00005.22 EPE29736.1 - 0.00018 21.8 0.0 0.00062 20.0 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 EPE29736.1 - 0.00021 21.2 0.2 0.0039 17.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPE29736.1 - 0.00047 20.2 0.0 0.002 18.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EPE29736.1 - 0.002 18.1 0.1 0.01 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 EPE29736.1 - 0.002 16.8 0.0 0.0035 16.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EPE29736.1 - 0.0023 18.7 2.2 0.01 16.6 0.9 2.8 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.1 EPE29736.1 - 0.0038 16.7 0.0 0.0097 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EPE29736.1 - 0.0054 15.6 0.0 0.0089 14.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Septin PF00735.13 EPE29736.1 - 0.0083 15.1 0.3 0.023 13.7 0.0 1.8 2 0 0 2 2 2 1 Septin MobB PF03205.9 EPE29736.1 - 0.0094 15.6 0.1 0.033 13.9 0.1 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EPE29736.1 - 0.012 15.4 0.2 0.057 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EPE29736.1 - 0.017 14.5 0.6 0.088 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain NACHT PF05729.7 EPE29736.1 - 0.022 14.4 0.1 0.066 12.8 0.1 1.8 1 0 0 1 1 1 0 NACHT domain DUF1599 PF07659.6 EPE29736.1 - 0.035 14.1 1.1 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1599) RNA_helicase PF00910.17 EPE29736.1 - 0.039 14.1 0.0 0.095 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EPE29736.1 - 0.05 13.2 2.0 0.1 12.3 0.0 2.6 3 0 0 3 3 3 0 Archaeal ATPase NTPase_1 PF03266.10 EPE29736.1 - 0.055 13.1 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 1 0 NTPase Viral_helicase1 PF01443.13 EPE29736.1 - 0.061 12.8 0.0 0.23 10.9 0.0 2.0 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EPE29736.1 - 0.066 12.7 0.5 0.31 10.5 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EPE29736.1 - 0.42 10.8 5.2 0.6 10.3 1.9 2.4 2 1 0 2 2 2 0 AAA domain Oxidored_FMN PF00724.15 EPE29737.1 - 3.6e-71 239.9 0.0 5.4e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Polysacc_deac_1 PF01522.16 EPE29739.1 - 4.3e-15 55.4 0.0 8.1e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Methyltransf_PK PF05891.7 EPE29740.1 - 1.8e-77 259.5 0.0 2.1e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EPE29740.1 - 0.00011 21.9 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EPE29740.1 - 0.0031 16.7 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EPE29740.1 - 0.046 14.3 0.1 0.31 11.6 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 EPE29742.1 - 4.6e-58 196.4 0.0 5.9e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPE29742.1 - 2.3e-23 82.5 0.0 2.5e-22 79.1 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EPE29742.1 - 1.7e-22 79.5 0.1 9.2e-22 77.1 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EPE29742.1 - 1.3e-20 73.4 0.0 1.9e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EPE29742.1 - 5.3e-20 71.2 0.0 8.8e-20 70.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPE29742.1 - 3e-07 30.6 0.0 5.7e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPE29742.1 - 0.00063 19.7 0.0 0.07 13.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase CPSF_A PF03178.10 EPE29743.1 - 9.2e-99 330.5 0.0 2.3e-97 325.9 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EPE29743.1 - 5.6e-69 232.6 0.0 9.3e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EPE29743.1 - 0.015 15.1 0.1 0.079 12.8 0.0 2.3 1 0 0 1 1 1 0 WD domain, G-beta repeat LysM PF01476.15 EPE29744.1 - 0.0021 17.9 0.0 0.0059 16.4 0.0 1.7 2 0 0 2 2 2 1 LysM domain Prok-RING_4 PF14447.1 EPE29744.1 - 0.06 12.8 3.8 0.13 11.7 2.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 EPE29744.1 - 0.16 11.8 7.4 0.37 10.6 5.1 1.7 1 1 0 1 1 1 0 Ring finger domain FYVE PF01363.16 EPE29744.1 - 0.32 10.9 5.3 0.79 9.6 3.6 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_2 PF13923.1 EPE29744.1 - 0.5 10.4 9.4 0.11 12.5 3.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE29744.1 - 0.55 10.0 9.2 1.5 8.5 6.3 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE29744.1 - 3.1 7.5 8.6 3.6 7.3 3.3 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) His_Phos_2 PF00328.17 EPE29745.1 - 1.3e-24 87.1 0.0 1.9e-23 83.3 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ribosomal_L18p PF00861.17 EPE29746.1 - 4.3e-43 146.3 0.1 7.9e-43 145.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EPE29746.1 - 3.6e-30 104.3 7.7 3.6e-30 104.3 5.3 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region LRR_4 PF12799.2 EPE29747.1 - 0.00013 21.4 3.2 0.48 10.0 0.1 5.0 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EPE29747.1 - 0.025 14.5 10.4 26 5.2 0.0 6.6 8 0 0 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 EPE29747.1 - 0.46 10.9 4.9 2.3e+02 2.7 0.0 6.0 8 0 0 8 8 8 0 Leucine rich repeat DUF3129 PF11327.3 EPE29751.1 - 9.1e-70 234.2 14.7 4.3e-69 232.0 10.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3129) HET PF06985.6 EPE29752.1 - 2.6e-26 92.4 0.0 6.1e-26 91.2 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PM0188 PF11477.3 EPE29752.1 - 0.095 11.5 0.0 0.21 10.3 0.0 1.5 2 0 0 2 2 2 0 Sialyltransferase PMO188 Ank_2 PF12796.2 EPE29753.1 - 4.8e-07 30.0 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE29753.1 - 0.0016 18.1 0.1 0.5 10.2 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EPE29753.1 - 0.0028 17.7 0.2 1.5 9.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EPE29753.1 - 0.007 16.8 0.1 0.02 15.4 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) NACHT PF05729.7 EPE29754.1 - 4.6e-05 23.1 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPE29754.1 - 0.004 17.1 0.0 0.48 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain fn3 PF00041.16 EPE29755.1 - 4.2e-06 26.8 0.0 1.2e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain COesterase PF00135.23 EPE29756.1 - 4.2e-80 269.9 0.0 5.4e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE29756.1 - 0.00011 21.8 0.0 0.00045 19.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold ERO1 PF04137.10 EPE29757.1 - 2.4e-137 457.7 0.0 2.8e-137 457.5 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) CKS PF01111.14 EPE29758.1 - 5.8e-37 125.3 1.3 7.2e-37 125.0 0.9 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 EPE29758.1 - 0.079 12.9 2.2 0.73 9.9 0.3 2.5 2 0 0 2 2 2 0 APC 15 residue motif Bromodomain PF00439.20 EPE29759.1 - 3.8e-34 116.4 2.2 2.4e-17 62.6 0.1 2.4 2 0 0 2 2 2 2 Bromodomain HSP70 PF00012.15 EPE29760.1 - 8.3e-230 763.7 9.7 9.2e-230 763.6 6.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPE29760.1 - 5e-16 58.2 0.2 4.1e-15 55.2 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EPE29760.1 - 9.7e-05 22.0 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MRC1 PF09444.5 EPE29760.1 - 0.32 11.3 6.8 0.088 13.1 2.1 1.9 2 0 0 2 2 2 0 MRC1-like domain RRF PF01765.14 EPE29761.1 - 4.3e-36 123.8 3.0 5.5e-36 123.5 2.0 1.1 1 0 0 1 1 1 1 Ribosome recycling factor Guanylate_kin PF00625.16 EPE29761.1 - 0.004 16.6 0.3 0.26 10.7 0.1 2.4 2 1 0 2 2 2 2 Guanylate kinase Methyltrans_RNA PF04452.9 EPE29761.1 - 0.011 14.8 0.0 1.2 8.1 0.0 2.6 2 1 0 2 2 2 0 RNA methyltransferase YscK PF06578.7 EPE29761.1 - 0.027 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) FadR_C PF07840.7 EPE29762.1 - 0.034 13.7 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 FadR C-terminal domain CLIP PF12032.3 EPE29762.1 - 0.12 12.4 0.1 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Regulatory CLIP domain of proteinases APC_CDC26 PF10471.4 EPE29763.1 - 1.8e-17 63.8 4.2 2.7e-17 63.2 2.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Spo12 PF05032.7 EPE29763.1 - 0.33 10.6 1.7 1.4 8.5 0.2 2.4 2 0 0 2 2 2 0 Spo12 family vMSA PF00695.14 EPE29763.1 - 0.43 9.7 3.5 0.67 9.0 2.5 1.3 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus UCN2 PF11613.3 EPE29763.1 - 1.5 8.8 4.1 0.69 9.9 0.9 1.7 2 0 0 2 2 2 0 Agonist of corticotropin releasing factor R2, Urocortin-2 Peptidase_M1 PF01433.15 EPE29764.1 - 3.6e-11 42.8 0.0 0.00017 20.8 0.0 3.3 2 1 0 3 3 3 3 Peptidase family M1 DUF3822 PF12864.2 EPE29764.1 - 0.047 12.9 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) UL97 PF06734.7 EPE29764.1 - 0.18 11.1 0.1 0.37 10.1 0.1 1.4 1 0 0 1 1 1 0 UL97 SAS4 PF15460.1 EPE29765.1 - 7.5e-36 122.0 3.2 2.4e-35 120.4 2.2 1.9 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 EPE29765.1 - 0.0019 18.6 0.8 0.0019 18.6 0.6 4.1 3 2 0 3 3 3 1 PEHE domain Adaptin_binding PF10199.4 EPE29765.1 - 0.022 15.0 2.3 0.022 15.0 1.6 2.9 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Response_reg PF00072.19 EPE29766.1 - 5e-22 78.0 0.5 1.3e-21 76.6 0.3 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EPE29766.1 - 6.1e-20 71.0 0.0 1.2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EPE29766.1 - 1.8e-09 37.8 0.0 1.2e-05 25.6 0.0 2.8 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 EPE29766.1 - 4.8e-08 32.8 0.9 1.9e-07 30.9 0.6 2.1 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EPE29766.1 - 1.2e-05 25.0 0.0 0.00015 21.4 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 EPE29766.1 - 0.00043 20.3 0.1 0.00093 19.2 0.1 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EPE29766.1 - 0.00048 20.1 0.0 0.072 13.1 0.0 2.9 2 0 0 2 2 2 1 PAS fold GAF_3 PF13492.1 EPE29766.1 - 0.03 14.4 0.0 0.09 12.8 0.0 1.9 1 0 0 1 1 1 0 GAF domain Thioredoxin_4 PF13462.1 EPE29767.1 - 0.00022 21.2 0.0 0.00052 20.0 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EPE29767.1 - 0.015 14.8 0.0 0.046 13.2 0.0 1.7 2 0 0 2 2 2 0 DSBA-like thioredoxin domain SKG6 PF08693.5 EPE29768.1 - 3.9e-12 45.2 0.1 3.9e-12 45.2 0.1 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EPE29768.1 - 0.0071 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.6 EPE29768.1 - 0.056 13.0 3.6 0.091 12.3 2.5 1.4 1 0 0 1 1 1 0 Podoplanin Syndecan PF01034.15 EPE29768.1 - 0.09 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Atrophin-1 PF03154.10 EPE29768.1 - 5.3 5.0 12.6 7.2 4.6 8.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family Pkinase PF00069.20 EPE29769.1 - 6e-19 68.1 0.0 2.2e-18 66.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain PX PF00787.19 EPE29769.1 - 1.4e-12 47.4 0.0 2.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 PX domain Pkinase_Tyr PF07714.12 EPE29769.1 - 0.0051 15.9 0.0 0.089 11.8 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase DUF4626 PF15422.1 EPE29769.1 - 0.047 13.6 0.4 0.082 12.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4626) CDP-OH_P_transf PF01066.16 EPE29771.1 - 1e-16 61.0 5.0 1e-16 61.0 3.5 2.4 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase GRAB PF10375.4 EPE29771.1 - 0.12 12.0 0.1 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 GRIP-related Arf-binding domain IQ PF00612.22 EPE29772.1 - 0.012 15.1 0.3 0.054 13.1 0.2 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF3611 PF12263.3 EPE29773.1 - 0.02 14.2 0.1 0.02 14.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DctQ PF04290.7 EPE29773.1 - 0.047 13.4 0.0 0.051 13.3 0.0 1.0 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF4282 PF14110.1 EPE29773.1 - 0.1 12.8 0.1 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF2681 PF10883.3 EPE29773.1 - 0.12 12.5 0.1 0.14 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF2404 PF10296.4 EPE29777.1 - 0.0072 16.4 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) VPS28 PF03997.7 EPE29778.1 - 6.1e-54 182.5 0.1 7.1e-54 182.2 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 EPE29778.1 - 0.093 12.5 1.9 6.1 6.7 0.1 2.3 2 0 0 2 2 2 0 Gas vesicle protein G Fungal_trans PF04082.13 EPE29780.1 - 3.5e-23 81.7 0.0 6.1e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE29780.1 - 4.7e-08 32.8 13.7 1.1e-07 31.5 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shugoshin_N PF07558.6 EPE29780.1 - 0.011 15.4 0.5 0.02 14.6 0.3 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.13 EPE29780.1 - 0.03 14.2 0.4 0.06 13.3 0.3 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.7 EPE29780.1 - 0.043 13.5 1.1 0.069 12.8 0.8 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Nha1_C PF08619.5 EPE29781.1 - 2.8e-77 260.8 53.4 1.1e-72 245.7 24.6 3.1 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EPE29781.1 - 5.7e-68 229.1 19.9 7.4e-68 228.8 13.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family p450 PF00067.17 EPE29781.1 - 5.8e-45 153.6 0.0 9.3e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 YrhC PF14143.1 EPE29781.1 - 0.46 10.4 2.1 0.58 10.1 0.1 2.1 2 0 0 2 2 2 0 YrhC-like protein MFS_1 PF07690.11 EPE29782.1 - 1.4e-40 139.1 47.7 7.8e-40 136.6 33.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EPE29783.1 - 3e-19 68.9 0.3 5e-19 68.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE29783.1 - 1.6e-09 37.4 9.4 2.8e-09 36.7 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rick_17kDa_Anti PF05433.10 EPE29784.1 - 0.014 15.0 0.3 0.03 13.9 0.2 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Glyco_tranf_2_4 PF13704.1 EPE29785.1 - 8.5e-06 26.0 0.0 1.7e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 EPE29785.1 - 0.0028 17.0 0.0 0.005 16.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 92 bZIP_1 PF00170.16 EPE29786.1 - 6.4e-11 42.0 10.1 2.4e-10 40.1 7.0 2.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPE29786.1 - 4e-05 23.3 9.7 4e-05 23.3 6.7 2.6 2 0 0 2 2 2 1 Basic region leucine zipper Amidase PF01425.16 EPE29787.1 - 2.5e-92 310.0 0.0 2.9e-92 309.8 0.0 1.0 1 0 0 1 1 1 1 Amidase HET PF06985.6 EPE29788.1 - 6e-24 84.7 0.6 1.3e-23 83.6 0.4 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sporozoite_P67 PF05642.6 EPE29789.1 - 0.00017 19.6 2.4 0.00017 19.6 1.7 1.4 2 0 0 2 2 2 1 Sporozoite P67 surface antigen AT_hook PF02178.14 EPE29789.1 - 0.3 10.9 8.0 1.3 8.9 5.5 2.2 1 0 0 1 1 1 0 AT hook motif Nucleoplasmin PF03066.10 EPE29789.1 - 0.38 10.2 19.2 0.31 10.5 9.6 2.2 2 0 0 2 2 2 0 Nucleoplasmin Nop53 PF07767.6 EPE29789.1 - 0.38 9.6 20.0 0.041 12.8 7.7 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Spt5_N PF11942.3 EPE29789.1 - 0.61 10.7 22.4 0.13 12.8 9.4 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 EPE29789.1 - 0.84 7.5 19.6 0.024 12.6 7.9 2.0 2 0 0 2 2 2 0 CDC45-like protein Sigma70_ner PF04546.8 EPE29789.1 - 0.88 9.1 16.9 2.5 7.6 7.6 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Prothymosin PF03247.9 EPE29789.1 - 1.7 8.8 30.1 0.64 10.1 12.5 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF3381 PF11861.3 EPE29789.1 - 2.4 7.6 21.2 2.1 7.8 7.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Myc_N PF01056.13 EPE29789.1 - 4.4 6.3 13.7 1.2 8.1 5.3 2.1 2 0 0 2 2 2 0 Myc amino-terminal region PRP21_like_P PF12230.3 EPE29789.1 - 7.8 5.9 17.3 0.66 9.4 5.8 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Zn_clus PF00172.13 EPE29791.1 - 4e-07 29.8 11.6 6.4e-07 29.1 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 EPE29792.1 - 5.4e-45 153.3 0.2 1.1e-44 152.3 0.2 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 EPE29792.1 - 4.6e-05 23.2 0.0 0.00019 21.3 0.0 2.0 2 0 0 2 2 2 1 U-box domain FGGY_C PF02782.11 EPE29795.1 - 1.7e-73 246.4 0.7 2.6e-73 245.8 0.5 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EPE29795.1 - 2.7e-67 226.6 0.0 3.9e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Thiolase_N PF00108.18 EPE29796.1 - 5.1e-77 258.4 0.4 8e-77 257.7 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPE29796.1 - 1.2e-44 150.6 0.3 3e-44 149.3 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EPE29796.1 - 0.092 12.7 0.0 0.32 11.0 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ran_BP1 PF00638.13 EPE29798.1 - 1.8e-50 170.0 1.8 2.8e-50 169.4 1.3 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EPE29798.1 - 3e-06 26.9 0.6 1.7e-05 24.5 0.4 1.9 1 1 0 1 1 1 1 WH1 domain Acyl-CoA_dh_2 PF08028.6 EPE29798.1 - 0.018 15.2 0.3 0.046 13.9 0.2 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain FHIPEP PF00771.15 EPE29798.1 - 0.13 10.5 0.4 0.17 10.1 0.3 1.2 1 0 0 1 1 1 0 FHIPEP family YEATS PF03366.11 EPE29799.1 - 1.2e-21 76.2 0.0 2.2e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 YEATS family DUF3083 PF11281.3 EPE29799.1 - 0.01 14.9 0.1 0.051 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3083) SLX9 PF15341.1 EPE29799.1 - 0.19 12.1 3.9 0.38 11.2 2.0 1.8 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 DUF4604 PF15377.1 EPE29800.1 - 1.4e-19 70.8 18.3 1.6e-19 70.6 12.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Lin-8 PF03353.10 EPE29800.1 - 0.89 8.7 10.2 1.2 8.3 7.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Glyco_transf_15 PF01793.11 EPE29801.1 - 7e-133 442.6 1.2 8.9e-133 442.3 0.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4048 PF13257.1 EPE29801.1 - 0.1 12.2 0.1 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4048) MFS_1 PF07690.11 EPE29802.1 - 4e-28 98.1 45.1 2.2e-20 72.6 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.22 EPE29804.1 - 2.1e-45 152.3 9.1 2.4e-17 62.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Vps55 PF04133.9 EPE29811.1 - 2.6e-46 156.2 4.3 2.9e-46 156.1 3.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 GtrA PF04138.9 EPE29811.1 - 0.09 12.7 2.3 0.22 11.4 1.6 1.6 1 1 0 1 1 1 0 GtrA-like protein Proteasome PF00227.21 EPE29812.1 - 2.6e-49 167.0 0.0 3.5e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPE29812.1 - 4.5e-11 41.8 0.2 7.1e-11 41.2 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lysine_decarbox PF03641.9 EPE29813.1 - 1.4e-30 105.8 0.0 2.1e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase CLPTM1 PF05602.7 EPE29814.1 - 1.6e-167 557.6 0.3 2e-167 557.3 0.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Longin PF13774.1 EPE29815.1 - 3.1e-27 93.9 0.7 5.8e-27 93.0 0.5 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EPE29815.1 - 3.9e-16 58.4 0.0 4.4e-15 55.0 0.0 2.2 2 0 0 2 2 2 1 Synaptobrevin EMP24_GP25L PF01105.19 EPE29815.1 - 0.035 13.8 3.8 2 8.0 0.4 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.7 EPE29815.1 - 0.15 11.8 0.7 0.46 10.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF334 PF03904.8 EPE29815.1 - 1.3 8.3 3.8 4.3 6.5 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF334) GMC_oxred_N PF00732.14 EPE29817.1 - 5.2e-25 88.2 0.1 9.9e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE29817.1 - 1.7e-19 70.5 0.0 9e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EPE29817.1 - 1.2e-06 27.7 0.3 0.00011 21.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE29817.1 - 4.6e-06 25.7 1.2 0.0048 15.8 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EPE29817.1 - 5.1e-05 23.4 0.1 0.00041 20.4 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE29817.1 - 6.2e-05 22.9 0.1 0.0003 20.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE29817.1 - 0.0014 18.5 0.1 0.0028 17.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE29817.1 - 0.0037 15.8 0.2 0.0054 15.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EPE29817.1 - 0.004 16.2 0.4 0.0078 15.3 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EPE29817.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EPE29817.1 - 0.19 10.5 0.1 0.3 9.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HET PF06985.6 EPE29819.1 - 5.1e-37 127.1 0.3 1.1e-36 126.0 0.2 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) XH PF03469.9 EPE29820.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.5 1 1 0 1 1 1 0 XH domain Chorismate_bind PF00425.13 EPE29821.1 - 3.7e-67 226.3 0.0 2.9e-40 138.2 0.0 2.2 1 1 1 2 2 2 2 chorismate binding enzyme GATase PF00117.23 EPE29821.1 - 4.3e-23 81.7 0.0 1.2e-15 57.4 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EPE29821.1 - 1e-14 54.7 0.0 2.3e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EPE29821.1 - 0.00024 20.6 0.1 0.0057 16.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase C26 DUF4116 PF13475.1 EPE29821.1 - 0.07 12.6 0.0 3.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Mso1_Sec1_bdg PF14475.1 EPE29822.1 - 3.1e-08 32.8 0.0 5.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 EPE29823.1 - 3.2e-33 114.5 0.8 3.2e-33 114.5 0.6 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EPE29823.1 - 1.1e-19 70.3 32.4 1.2e-19 70.1 14.0 3.4 2 1 0 2 2 2 1 Mak16 protein C-terminal region SMN PF06003.7 EPE29823.1 - 0.031 13.3 3.0 0.058 12.4 2.1 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) CENP-T PF15511.1 EPE29823.1 - 0.29 10.3 11.1 0.38 9.9 7.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EPE29823.1 - 0.44 8.3 27.5 0.65 7.8 19.1 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 EPE29823.1 - 1.3 7.2 23.1 1.6 6.9 16.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Stm1_N PF09598.5 EPE29823.1 - 9.4 7.0 9.0 5.2 7.8 1.1 2.5 2 0 0 2 2 2 0 Stm1 DUF1996 PF09362.5 EPE29824.1 - 1.9e-83 279.7 2.1 2.6e-83 279.2 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gal_mutarotas_2 PF13802.1 EPE29824.1 - 0.018 14.8 1.0 0.69 9.8 0.1 2.4 2 0 0 2 2 2 0 Galactose mutarotase-like Peptidase_S8 PF00082.17 EPE29825.1 - 0.00012 21.3 0.1 0.43 9.6 0.0 2.9 2 1 1 3 3 3 2 Subtilase family Ank_4 PF13637.1 EPE29825.1 - 0.00032 21.1 0.1 1.2 9.6 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPE29825.1 - 0.00058 20.1 0.1 0.23 11.8 0.0 3.3 2 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPE29825.1 - 0.0013 18.8 0.1 2.7 8.5 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 EPE29825.1 - 0.0096 15.6 0.2 6.1 6.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EPE29825.1 - 0.018 15.2 0.0 12 6.2 0.0 3.8 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPE29826.1 - 1.8e-122 399.9 32.8 2.1e-18 66.4 0.3 12.4 6 3 6 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 EPE29826.1 - 2e-105 339.7 40.4 4e-08 32.6 0.1 24.4 23 1 0 23 23 23 19 Ankyrin repeat Ank_5 PF13857.1 EPE29826.1 - 5.9e-77 251.9 31.8 3.2e-09 36.7 0.2 18.4 10 6 11 21 21 21 14 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE29826.1 - 2.6e-72 237.9 29.5 1.4e-09 38.2 0.0 16.0 9 4 7 17 17 17 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE29826.1 - 8.3e-70 223.7 38.6 1.4e-05 24.9 0.0 24.5 26 1 1 27 27 27 15 Ankyrin repeat SPRY PF00622.23 EPE29826.1 - 2.9e-14 53.2 0.4 5.5e-14 52.3 0.3 1.4 1 0 0 1 1 1 1 SPRY domain DUF1843 PF08898.5 EPE29826.1 - 0.75 9.8 7.2 14 5.8 0.1 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) DUF4448 PF14610.1 EPE29828.1 - 0.00062 19.3 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Elong_Iki1 PF10483.4 EPE29829.1 - 3.9e-65 220.0 0.0 5.2e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 Glyco_hydro_63 PF03200.11 EPE29830.1 - 3e-238 792.7 0.1 2.5e-237 789.6 0.1 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EPE29830.1 - 0.0017 17.0 0.2 0.0031 16.2 0.1 1.3 1 0 0 1 1 1 1 Trehalase DUF1777 PF08648.7 EPE29831.1 - 1.5e-22 80.1 74.5 8.7e-15 54.9 51.6 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) Ank_2 PF12796.2 EPE29832.1 - 0.0051 17.1 0.0 0.23 11.8 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Apc4 PF12896.2 EPE29832.1 - 0.05 12.8 0.3 0.16 11.2 0.2 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Ank PF00023.25 EPE29832.1 - 0.073 12.9 0.8 0.98 9.3 0.0 3.0 3 1 0 3 3 3 0 Ankyrin repeat TPK_catalytic PF04263.11 EPE29832.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain p450 PF00067.17 EPE29833.1 - 7.7e-49 166.4 0.0 9.6e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FTA2 PF13095.1 EPE29835.1 - 8.3e-24 84.3 0.0 1.1e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 TrmE_N PF10396.4 EPE29836.1 - 2.5e-32 111.2 0.0 6.3e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EPE29836.1 - 4.3e-21 75.1 0.2 1.5e-20 73.3 0.2 2.0 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EPE29836.1 - 9e-18 64.3 0.1 4.3e-17 62.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPE29836.1 - 2.2e-08 34.0 0.5 8.3e-08 32.2 0.1 2.2 2 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 EPE29836.1 - 1.9e-05 23.9 0.0 3.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EPE29836.1 - 5.7e-05 23.5 0.0 0.00019 21.8 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein cobW PF02492.14 EPE29836.1 - 0.0038 16.6 0.3 0.042 13.3 0.2 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 EPE29836.1 - 0.012 15.0 0.0 4.4 6.6 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EPE29836.1 - 0.039 13.1 0.0 1.6 7.9 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family Glyco_hydro_3_C PF01915.17 EPE29836.1 - 0.044 13.2 0.7 0.17 11.3 0.2 2.0 2 1 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain ABC_tran PF00005.22 EPE29836.1 - 0.06 13.6 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EPE29836.1 - 0.097 12.6 0.4 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain PTS_IIB PF02302.12 EPE29836.1 - 0.13 12.7 1.1 0.79 10.2 0.0 2.3 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit HATPase_c PF02518.21 EPE29838.1 - 4.8e-17 61.6 0.1 1.3e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EPE29838.1 - 1.2e-12 47.6 0.1 3.4e-12 46.1 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EPE29838.1 - 4.2e-12 46.0 0.1 9.4e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain GAF_2 PF13185.1 EPE29838.1 - 0.016 15.6 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 GAF domain RabGAP-TBC PF00566.13 EPE29839.1 - 3.2e-34 118.2 2.4 7.2e-34 117.1 1.7 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EPE29839.1 - 8e-10 38.3 0.0 1.2e-05 24.7 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF3548) NOA36 PF06524.7 EPE29841.1 - 3.5 6.8 6.1 3.8 6.6 4.2 1.0 1 0 0 1 1 1 0 NOA36 protein Asp PF00026.18 EPE29842.1 - 1.3e-19 70.6 0.1 2e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Adeno_E3_CR2 PF02439.10 EPE29842.1 - 0.31 10.6 0.5 0.59 9.7 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MRJP PF03022.11 EPE29845.1 - 1.5e-24 86.7 0.0 2.5e-24 86.0 0.0 1.3 1 1 0 1 1 1 1 Major royal jelly protein NHL PF01436.16 EPE29845.1 - 0.11 12.4 0.0 5.6 7.1 0.0 2.8 2 0 0 2 2 2 0 NHL repeat GFA PF04828.9 EPE29846.1 - 4.4e-07 29.7 3.2 4.4e-07 29.7 2.3 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EPE29846.1 - 0.022 14.2 2.0 0.037 13.5 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Yippee-Mis18 PF03226.9 EPE29846.1 - 0.074 13.0 3.5 0.1 12.6 2.4 1.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF678 PF05077.7 EPE29846.1 - 1.8 8.5 5.1 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) MMtag PF10159.4 EPE29847.1 - 3.5e-30 103.8 5.5 3.5e-30 103.8 3.8 2.6 3 1 0 3 3 3 1 Kinase phosphorylation protein Ribonuc_L-PSP PF01042.16 EPE29848.1 - 5.7e-19 68.0 0.0 6.9e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peroxidase_2 PF01328.12 EPE29850.1 - 7.3e-40 136.5 0.3 7.3e-40 136.5 0.2 1.5 2 0 0 2 2 2 1 Peroxidase, family 2 HET PF06985.6 EPE29850.1 - 1.4e-21 77.0 0.1 2.6e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3684 PF12449.3 EPE29851.1 - 0 1361.4 0.0 0 1361.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EPE29851.1 - 0.00029 20.4 0.0 0.0013 18.3 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Complex1_LYR_1 PF13232.1 EPE29852.1 - 0.04 14.1 2.8 1.2 9.3 0.5 3.3 3 0 0 3 3 3 0 Complex1_LYR-like CorA PF01544.13 EPE29854.1 - 8.4e-11 41.4 3.0 3.1e-10 39.5 0.3 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Nup54 PF13874.1 EPE29855.1 - 0.15 11.6 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Med6 PF04934.9 EPE29857.1 - 4.3e-40 136.4 0.0 6e-40 136.0 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component HA2 PF04408.18 EPE29858.1 - 1.3e-18 66.8 0.0 4.3e-18 65.2 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPE29858.1 - 2.9e-13 49.4 0.0 1.3e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EPE29858.1 - 3e-13 49.6 0.0 7.3e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EPE29858.1 - 1.1e-07 31.5 0.3 2.3e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPE29858.1 - 0.00046 20.3 0.1 0.0023 18.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EPE29858.1 - 0.0088 14.9 0.1 0.025 13.4 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 EPE29858.1 - 0.082 13.2 0.1 0.082 13.2 0.0 3.4 3 1 0 3 3 3 0 AAA domain ResIII PF04851.10 EPE29858.1 - 0.42 10.4 0.0 0.42 10.4 0.0 4.0 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit RdRP PF05183.7 EPE29858.1 - 0.67 8.5 6.6 6 5.4 0.0 3.0 3 0 0 3 3 3 0 RNA dependent RNA polymerase DUF2372 PF10178.4 EPE29859.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) DIOX_N PF14226.1 EPE29860.1 - 1.9e-23 83.1 0.0 3.7e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPE29860.1 - 1.3e-19 70.3 0.0 2.6e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 EPE29861.1 - 2e-104 349.5 42.3 2.5e-104 349.3 29.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COesterase PF00135.23 EPE29862.1 - 3.5e-74 250.4 1.2 6.2e-74 249.6 0.8 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE29862.1 - 9.7e-07 28.5 0.1 6e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE29862.1 - 0.02 14.0 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S10 PF00450.17 EPE29863.1 - 4.2e-82 276.5 0.1 5.7e-82 276.1 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DivIC PF04977.10 EPE29864.1 - 0.00015 21.1 16.3 0.024 14.1 0.0 4.4 3 1 1 4 4 4 1 Septum formation initiator TPR_MLP1_2 PF07926.7 EPE29864.1 - 0.00077 19.2 16.4 0.049 13.3 2.1 3.4 3 0 0 3 3 3 2 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EPE29864.1 - 0.0031 16.5 12.9 0.0033 16.4 2.1 2.2 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 Microtub_assoc PF07989.6 EPE29864.1 - 0.0032 17.2 16.5 0.07 12.9 0.3 4.5 2 2 2 4 4 4 1 Microtubule associated DUF3509 PF12021.3 EPE29864.1 - 0.023 14.4 1.0 0.079 12.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) HALZ PF02183.13 EPE29864.1 - 0.027 14.1 13.8 0.52 10.0 1.6 4.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper DUF972 PF06156.8 EPE29864.1 - 0.078 13.3 22.1 0.071 13.4 1.5 4.4 3 2 1 4 4 4 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EPE29864.1 - 0.12 12.3 11.0 2.8 7.9 0.1 4.1 3 1 0 3 3 3 0 bZIP transcription factor DUF2570 PF10828.3 EPE29864.1 - 0.18 11.4 0.1 0.18 11.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) IncA PF04156.9 EPE29864.1 - 0.69 9.4 16.4 0.36 10.4 0.5 2.5 2 0 0 2 2 2 0 IncA protein DUF342 PF03961.8 EPE29864.1 - 0.92 7.8 6.9 2.7 6.3 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) PilJ PF13675.1 EPE29864.1 - 2.8 8.2 8.0 4.2 7.7 0.8 2.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.7 EPE29864.1 - 3.2 7.5 8.8 3.2 7.5 0.6 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Mnd1 PF03962.10 EPE29864.1 - 5.2 6.6 17.1 3.1 7.4 3.7 3.0 2 1 1 3 3 3 0 Mnd1 family Rieske_2 PF13806.1 EPE29865.1 - 0.14 11.8 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain Pkinase PF00069.20 EPE29866.1 - 4.8e-25 88.2 0.0 8.5e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29866.1 - 2.4e-11 43.2 0.0 8.6e-11 41.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase ArsB PF02040.10 EPE29870.1 - 9.1e-15 54.5 24.7 3.8e-08 32.7 8.6 2.4 2 0 0 2 2 2 2 Arsenical pump membrane protein FH2 PF02181.18 EPE29872.1 - 6.8e-78 262.1 7.1 6.8e-78 262.1 4.9 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EPE29872.1 - 3.1e-68 228.8 0.0 3.1e-68 228.8 0.0 3.1 3 1 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EPE29872.1 - 6.4e-55 185.6 1.7 3.9e-54 183.0 0.6 2.6 1 1 1 2 2 2 1 Diaphanous FH3 Domain Sugar_tr PF00083.19 EPE29876.1 - 1.2e-120 403.2 25.1 1.3e-120 403.0 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE29876.1 - 2.1e-18 66.1 45.4 2.4e-17 62.6 27.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.4 EPE29877.1 - 8.7e-126 419.4 0.0 1.2e-125 418.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Aminotran_5 PF00266.14 EPE29878.1 - 3.2e-31 108.4 0.0 2.6e-20 72.5 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V adh_short PF00106.20 EPE29879.1 - 2.5e-05 24.2 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE29879.1 - 3e-05 23.9 0.0 4.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AMP-binding PF00501.23 EPE29880.1 - 8.9e-41 139.6 0.0 1.2e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TRAPPC9-Trs120 PF08626.6 EPE29881.1 - 1.3e-147 493.1 0.0 3e-147 491.9 0.0 1.6 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF3733 PF12534.3 EPE29881.1 - 0.051 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 ADH_zinc_N PF00107.21 EPE29883.1 - 1.1e-23 83.2 0.0 1.8e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE29883.1 - 6e-16 59.5 0.0 1e-15 58.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE29883.1 - 4e-05 23.3 0.0 8.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 EPE29883.1 - 0.0017 17.9 0.1 0.0048 16.5 0.0 1.7 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 EPE29883.1 - 0.0097 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HEAT_2 PF13646.1 EPE29884.1 - 2.9e-09 37.0 9.0 0.071 13.3 0.0 8.2 8 2 1 9 9 9 3 HEAT repeats HEAT PF02985.17 EPE29884.1 - 7e-09 35.0 7.7 0.76 10.0 0.0 9.5 11 0 0 11 11 11 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EPE29884.1 - 1.2e-05 25.6 0.0 0.16 12.3 0.0 4.3 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EPE29884.1 - 2.7e-05 23.6 1.1 1.7 7.9 0.0 4.4 4 0 0 4 4 4 2 CLASP N terminal Transcrip_reg PF01709.15 EPE29885.1 - 1.1e-50 172.0 4.3 7.9e-46 156.0 0.5 2.0 2 0 0 2 2 2 2 Transcriptional regulator ECH PF00378.15 EPE29887.1 - 1.6e-25 89.6 0.0 2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family cwf21 PF08312.7 EPE29888.1 - 6.7e-16 57.8 10.9 6.7e-16 57.8 7.6 1.9 2 0 0 2 2 2 1 cwf21 domain VIT1 PF01988.14 EPE29888.1 - 0.18 11.2 0.5 0.22 10.9 0.3 1.2 1 0 0 1 1 1 0 VIT family D123 PF07065.9 EPE29889.1 - 1.2e-93 313.5 0.0 2.4e-93 312.4 0.0 1.5 1 1 0 1 1 1 1 D123 DUF4343 PF14243.1 EPE29889.1 - 0.047 13.5 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) adh_short PF00106.20 EPE29890.1 - 2.3e-28 99.2 0.3 5.2e-28 98.0 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE29890.1 - 5.6e-24 85.2 0.0 7.8e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE29890.1 - 4.1e-13 49.3 0.3 1.3e-12 47.7 0.1 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EPE29890.1 - 0.0001 21.8 0.1 0.00017 21.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPE29890.1 - 0.0013 18.4 0.7 0.0032 17.2 0.5 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EPE29890.1 - 0.1 12.7 0.1 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EPE29890.1 - 0.12 11.2 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein A_deaminase PF00962.17 EPE29891.1 - 1.2e-42 146.0 0.0 2.9e-41 141.4 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase A_deaminase_N PF08451.6 EPE29891.1 - 0.0026 17.7 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Acetyltransf_1 PF00583.19 EPE29892.1 - 4.8e-17 61.7 0.4 3e-08 33.5 0.2 2.8 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE29892.1 - 8.1e-15 54.7 0.0 6.6e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE29892.1 - 2.2e-11 43.7 0.2 0.00012 21.9 0.1 3.5 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE29892.1 - 3.1e-08 33.7 0.0 0.0091 16.1 0.0 2.5 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE29892.1 - 2.3e-06 27.2 0.2 0.0036 17.0 0.1 2.8 2 1 0 2 2 2 2 FR47-like protein Acetyltransf_CG PF14542.1 EPE29892.1 - 2.3e-05 24.2 0.0 0.07 13.0 0.0 2.4 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.1 EPE29892.1 - 0.034 14.0 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EPE29892.1 - 0.11 12.1 0.0 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Cellulase PF00150.13 EPE29894.1 - 2.4e-47 161.4 0.3 3.3e-47 161.0 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PRNT PF15174.1 EPE29895.1 - 0.13 11.8 0.6 0.19 11.3 0.4 1.3 1 0 0 1 1 1 0 Prion-related protein testis-specific Hus1 PF04005.7 EPE29898.1 - 3.4e-98 328.1 0.0 3.8e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Phosphodiest PF01663.17 EPE29900.1 - 1e-14 54.6 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EPE29900.1 - 4.8e-06 26.1 1.3 8e-06 25.4 0.9 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EPE29900.1 - 0.001 18.3 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Gly-zipper_OmpA PF13436.1 EPE29900.1 - 0.045 13.4 0.5 0.11 12.0 0.3 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain UPF0220 PF05255.6 EPE29901.1 - 5.1e-66 221.0 5.2 5.7e-66 220.8 3.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) SMI1_KNR4 PF09346.5 EPE29902.1 - 3.9e-35 120.7 0.0 7.5e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Sec8_exocyst PF04048.9 EPE29903.1 - 2.3e-46 156.9 0.2 5.4e-46 155.7 0.2 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EPE29903.1 - 1.8e-07 30.3 0.7 3.1e-07 29.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) adh_short PF00106.20 EPE29905.1 - 1.2e-11 44.8 0.0 1.6e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE29905.1 - 0.001 18.7 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 KR domain STAS PF01740.16 EPE29905.1 - 0.018 14.4 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 STAS domain Polysacc_synt_2 PF02719.10 EPE29905.1 - 0.045 12.6 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pkinase PF00069.20 EPE29906.1 - 1.6e-53 181.5 0.0 2.5e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29906.1 - 1.2e-30 106.4 0.0 1.8e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE29906.1 - 9.8e-11 41.1 0.0 1.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PDZ_assoc PF10600.4 EPE29906.1 - 0.02 15.1 0.1 0.066 13.5 0.1 1.9 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors Kdo PF06293.9 EPE29906.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 EPE29906.1 - 0.055 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 PAS domain HAD_2 PF13419.1 EPE29907.1 - 4.6e-24 85.5 0.0 5.6e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPE29907.1 - 0.00014 22.3 0.0 0.00016 22.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EPE29907.1 - 0.04 13.5 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase Fes1 PF08609.5 EPE29908.1 - 1.4e-31 108.8 2.5 2.1e-31 108.2 0.2 2.2 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EPE29908.1 - 1.7e-05 24.9 0.8 6.9e-05 23.0 0.1 2.2 2 2 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EPE29908.1 - 0.00078 19.3 0.1 0.0078 16.2 0.0 2.4 2 0 0 2 2 2 1 HEAT repeat Arm PF00514.18 EPE29908.1 - 0.0047 16.7 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EPE29908.1 - 0.015 15.7 0.4 0.41 11.2 0.0 3.0 2 1 2 4 4 4 0 HEAT-like repeat ACP PF06857.6 EPE29908.1 - 0.071 13.0 0.3 0.16 11.8 0.2 1.6 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) DUF4066 PF13278.1 EPE29909.1 - 4.5e-28 97.5 0.0 5.8e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EPE29909.1 - 4.9e-11 42.2 0.0 6.9e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Aa_trans PF01490.13 EPE29910.1 - 2.3e-60 204.2 27.0 2.7e-60 203.9 18.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3321 PF11968.3 EPE29911.1 - 1.3e-88 296.2 0.1 1.8e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EPE29911.1 - 0.0046 16.7 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_L23eN PF03939.8 EPE29912.1 - 8.8e-21 73.6 12.0 8.8e-21 73.6 8.3 2.0 1 1 1 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EPE29912.1 - 2.1e-16 59.6 1.3 2.1e-16 59.6 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 CorA PF01544.13 EPE29913.1 - 6.9e-43 146.7 0.0 9.3e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein YmdB PF13277.1 EPE29913.1 - 0.021 13.8 0.1 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 YmdB-like protein SPC12 PF06645.8 EPE29914.1 - 2.2e-26 91.4 0.0 2.7e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.9 EPE29914.1 - 0.0025 18.1 0.1 0.003 17.8 0.1 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein Nucleos_tra2_N PF01773.15 EPE29914.1 - 0.033 14.5 0.3 0.076 13.3 0.2 1.6 1 1 1 2 2 2 0 Na+ dependent nucleoside transporter N-terminus MIP PF00230.15 EPE29914.1 - 0.078 12.4 0.1 0.097 12.1 0.1 1.1 1 0 0 1 1 1 0 Major intrinsic protein zf-rbx1 PF12678.2 EPE29915.1 - 4.2e-18 65.2 4.5 6.6e-18 64.5 3.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPE29915.1 - 7.5e-06 25.6 1.8 1.1e-05 25.1 1.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PNRC PF15365.1 EPE29916.1 - 4.7e-05 23.3 6.2 4.7e-05 23.3 4.3 4.3 4 1 0 4 4 4 2 Proline-rich nuclear receptor coactivator GIDA PF01134.17 EPE29917.1 - 6.3e-158 525.7 0.0 7.7e-158 525.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EPE29917.1 - 1e-18 67.1 0.1 3.9e-17 62.0 0.0 2.5 2 0 0 2 2 2 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EPE29917.1 - 1.5e-06 28.2 0.5 3.7e-06 26.9 0.4 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPE29917.1 - 2.1e-06 27.1 0.7 3.7e-06 26.2 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EPE29917.1 - 0.00074 18.5 3.0 0.19 10.6 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE29917.1 - 0.0034 16.2 3.0 0.0061 15.4 1.5 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EPE29917.1 - 0.0099 15.4 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EPE29917.1 - 0.11 10.9 2.6 0.3 9.5 0.5 2.2 2 0 0 2 2 2 0 HI0933-like protein Ala_racemase_N PF01168.15 EPE29919.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Pyridoxal_deC PF00282.14 EPE29920.1 - 8.3e-75 251.5 0.0 1.2e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EPE29920.1 - 2e-07 30.0 0.0 3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 EPE29920.1 - 0.03 12.8 0.0 0.068 11.7 0.0 1.6 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain WD40 PF00400.27 EPE29921.1 - 1.8e-50 167.0 22.3 1.5e-09 37.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EPE29921.1 - 0.00015 21.5 0.1 0.092 12.4 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WXG100 PF06013.7 EPE29921.1 - 0.39 10.7 4.5 0.49 10.4 1.2 2.5 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DivIC PF04977.10 EPE29921.1 - 0.52 9.8 2.3 0.94 9.0 1.6 1.4 1 0 0 1 1 1 0 Septum formation initiator Atg14 PF10186.4 EPE29921.1 - 0.55 9.1 5.0 0.92 8.3 3.2 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 A_deaminase PF00962.17 EPE29922.1 - 1.6e-27 96.3 0.0 1.7e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 EPE29922.1 - 0.007 16.4 0.0 0.052 13.5 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Tyr-DNA_phospho PF06087.7 EPE29923.1 - 5.8e-70 236.1 0.0 7.6e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EPE29923.1 - 2e-06 27.5 0.0 0.0023 17.6 0.0 3.0 3 0 0 3 3 3 2 PLD-like domain UIM PF02809.15 EPE29923.1 - 0.012 15.0 1.2 0.012 15.0 0.9 2.8 3 0 0 3 3 3 0 Ubiquitin interaction motif Gti1_Pac2 PF09729.4 EPE29924.1 - 5.9e-61 205.1 0.0 1.6e-60 203.8 0.0 1.7 1 0 0 1 1 1 1 Gti1/Pac2 family SRP1_TIP1 PF00660.12 EPE29924.1 - 0.089 12.6 0.5 5 7.0 0.1 2.4 2 0 0 2 2 2 0 Seripauperin and TIP1 family CDP-OH_P_transf PF01066.16 EPE29925.1 - 1.9e-16 60.1 6.1 1.9e-16 60.1 4.2 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase His_Phos_2 PF00328.17 EPE29927.1 - 3.1e-30 105.7 0.0 4e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PepX_N PF09168.5 EPE29930.1 - 0.098 12.8 0.1 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal HET PF06985.6 EPE29931.1 - 8.5e-21 74.5 3.9 6.5e-18 65.2 0.2 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Sec16_C PF12931.2 EPE29933.1 - 3.7e-96 322.2 0.1 5.1e-96 321.7 0.1 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EPE29933.1 - 4.8e-31 107.1 0.0 1.2e-30 105.9 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region E1-E2_ATPase PF00122.15 EPE29934.1 - 9.3e-17 60.8 0.0 1.9e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EPE29934.1 - 1.6e-15 58.1 0.0 4e-15 56.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPE29934.1 - 3.7e-09 37.0 0.0 1.1e-08 35.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPE29934.1 - 0.00047 20.0 0.0 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPE29934.1 - 0.003 17.1 0.0 0.0069 15.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAD_binding_6 PF00970.19 EPE29935.1 - 2.4e-08 33.9 0.0 5.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EPE29935.1 - 4.4e-08 33.6 0.0 2.9e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EPE29935.1 - 0.0087 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF3402 PF11882.3 EPE29937.1 - 3.3e-154 513.8 0.0 4.6e-154 513.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EPE29937.1 - 3.2e-82 275.6 0.1 4.3e-82 275.2 0.1 1.2 1 0 0 1 1 1 1 N1221-like protein Prok-E2_E PF14462.1 EPE29938.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family E CHAT PF12770.2 EPE29939.1 - 2.5e-38 131.8 0.1 4.5e-38 131.0 0.1 1.4 1 0 0 1 1 1 1 CHAT domain ZZ PF00569.12 EPE29939.1 - 1.4e-10 40.5 6.2 1.4e-10 40.5 4.3 2.0 2 0 0 2 2 2 1 Zinc finger, ZZ type Peptidase_C25 PF01364.13 EPE29939.1 - 0.009 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C25 BTB PF00651.26 EPE29940.1 - 2.6e-09 37.0 0.4 7.5e-08 32.3 0.3 2.4 1 1 0 1 1 1 1 BTB/POZ domain YopX PF09643.5 EPE29940.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 YopX protein Aldo_ket_red PF00248.16 EPE29941.1 - 2e-70 236.8 0.0 2.3e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 EPE29942.1 - 2.6e-06 27.2 7.1 7.2e-06 25.8 4.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE29942.1 - 0.00015 20.5 1.3 0.00048 18.8 0.9 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain EthD PF07110.6 EPE29943.1 - 1.1e-12 48.7 0.0 1.5e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 EthD domain Nop10p PF04135.7 EPE29946.1 - 0.025 14.3 0.5 6.6 6.5 0.1 3.4 3 0 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family ZZ PF00569.12 EPE29947.1 - 1.4 8.5 6.2 15 5.2 0.3 3.3 3 0 0 3 3 3 0 Zinc finger, ZZ type PGA2 PF07543.7 EPE29948.1 - 2e-22 79.4 5.6 5.4e-22 78.0 3.9 1.7 1 1 0 1 1 1 1 Protein trafficking PGA2 CENP-S PF15630.1 EPE29949.1 - 1.8e-33 114.5 0.0 2.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EPE29949.1 - 0.0025 17.5 0.0 0.0053 16.4 0.0 1.5 2 0 0 2 2 2 1 Bromodomain associated TEBP_beta PF07404.6 EPE29949.1 - 0.034 13.2 0.8 0.034 13.2 0.6 1.2 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) CENP-T PF15511.1 EPE29949.1 - 0.066 12.4 0.0 0.088 12.0 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SUR7 PF06687.7 EPE29950.1 - 0.023 14.2 7.4 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 SUR7/PalI family MARVEL PF01284.18 EPE29950.1 - 1.3 8.8 22.0 7.2 6.4 15.6 1.8 1 1 0 1 1 1 0 Membrane-associating domain ADH_N PF08240.7 EPE29951.1 - 2.1e-25 88.5 5.5 4e-25 87.7 3.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE29951.1 - 6.9e-16 57.9 0.0 1.3e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPE29951.1 - 0.00095 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EPE29951.1 - 0.0056 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DZR PF12773.2 EPE29951.1 - 0.0084 15.9 2.2 0.022 14.6 1.5 1.7 1 1 0 1 1 1 1 Double zinc ribbon PAR1 PF06521.6 EPE29951.1 - 0.3 10.6 3.0 0.17 11.4 0.4 1.8 1 1 0 2 2 2 0 PAR1 protein Fungal_trans PF04082.13 EPE29952.1 - 4e-36 124.2 0.1 8.2e-36 123.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE29952.1 - 7.7e-07 28.9 8.1 1.5e-06 28.0 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 EPE29954.1 - 4.2e-33 114.8 4.8 1.6e-32 112.9 2.4 2.0 2 0 0 2 2 2 1 Amidase zf-RING_2 PF13639.1 EPE29955.1 - 1.1e-09 37.9 8.9 1.7e-09 37.3 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE29955.1 - 2.1e-08 34.0 9.3 3.4e-08 33.3 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE29955.1 - 8.7e-08 31.7 5.8 1.4e-07 31.1 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE29955.1 - 9.8e-08 31.6 7.5 1.4e-07 31.0 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE29955.1 - 7.2e-07 28.7 9.3 1.2e-06 28.1 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPE29955.1 - 9e-07 28.6 9.6 1.5e-06 27.9 6.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EPE29955.1 - 1e-06 28.4 2.5 2.4e-06 27.2 1.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EPE29955.1 - 0.0001 22.3 5.0 0.00021 21.3 3.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EPE29955.1 - 0.0016 18.1 3.4 0.003 17.2 2.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EPE29955.1 - 0.0045 16.7 6.2 0.14 11.9 0.2 3.1 2 1 1 3 3 3 1 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EPE29955.1 - 0.015 14.7 8.4 0.026 14.0 5.8 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 EPE29955.1 - 0.021 14.4 6.9 0.041 13.4 4.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EPE29955.1 - 0.023 14.2 6.5 0.029 13.9 0.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TerY-C PF15616.1 EPE29955.1 - 0.034 14.0 1.6 0.058 13.3 1.1 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain DNA_ligase_ZBD PF03119.11 EPE29955.1 - 0.058 13.1 0.9 2.1 8.0 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RING_3 PF14369.1 EPE29955.1 - 0.078 12.9 0.7 0.078 12.9 0.5 1.9 2 0 0 2 2 2 0 zinc-finger DZR PF12773.2 EPE29955.1 - 0.14 12.0 4.2 0.44 10.4 2.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF1272 PF06906.6 EPE29955.1 - 0.31 10.9 5.0 0.66 9.8 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) MPLKIP PF15502.1 EPE29957.1 - 0.23 12.1 8.7 0.26 11.9 6.0 1.1 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein Gly-zipper_YMGG PF13441.1 EPE29958.1 - 0.00019 20.8 0.5 0.00028 20.3 0.3 1.2 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 EPE29958.1 - 0.00027 20.5 0.1 0.00039 20.0 0.1 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 EPE29958.1 - 0.00065 19.2 0.3 0.0013 18.3 0.2 1.4 1 0 0 1 1 1 1 Glycine zipper Pkinase PF00069.20 EPE29959.1 - 2e-27 96.0 0.0 2.5e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29959.1 - 2.6e-21 75.8 0.0 3.6e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE29959.1 - 0.011 14.6 0.0 0.021 13.8 0.0 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 EPE29959.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAP2 PF01569.16 EPE29960.1 - 4.8e-13 48.9 0.9 4.8e-13 48.9 0.6 1.7 1 1 1 2 2 2 1 PAP2 superfamily DUF2759 PF10958.3 EPE29960.1 - 0.0072 15.8 1.2 0.021 14.3 0.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2759) DUF212 PF02681.9 EPE29960.1 - 0.024 14.3 0.1 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family IBR PF01485.16 EPE29961.1 - 2.5e-19 68.9 31.6 7.6e-13 48.1 2.1 4.0 3 1 1 4 4 4 3 IBR domain RWD PF05773.17 EPE29961.1 - 5.1e-18 65.0 0.1 9.3e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 EPE29961.1 - 0.00027 20.7 7.5 0.00027 20.7 5.2 3.7 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 EPE29961.1 - 0.002 18.1 8.0 0.002 18.1 5.6 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE29961.1 - 0.0025 17.4 5.1 0.0025 17.4 3.6 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE29961.1 - 0.0064 16.2 4.4 0.0064 16.2 3.0 3.8 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPE29961.1 - 0.014 15.1 2.6 0.014 15.1 1.8 2.8 2 0 0 2 2 2 0 RING-type zinc-finger AA_permease_2 PF13520.1 EPE29962.1 - 3.8e-62 210.2 45.8 5.4e-62 209.7 31.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE29962.1 - 3.9e-27 94.7 30.5 3.9e-27 94.7 21.2 2.2 2 0 0 2 2 2 1 Amino acid permease tRNA-synt_1 PF00133.17 EPE29963.1 - 1.1e-50 172.3 0.1 3.3e-17 61.7 0.1 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EPE29963.1 - 3.3e-40 137.3 0.0 6.3e-40 136.4 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EPE29963.1 - 3.9e-28 98.1 0.1 3.7e-21 75.2 0.0 4.0 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EPE29963.1 - 5.8e-11 42.3 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EPE29963.1 - 0.0023 16.8 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EPE29963.1 - 0.0032 16.6 0.0 0.28 10.2 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.1 EPE29963.1 - 0.14 11.4 1.7 7.1 5.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_S8 PF00082.17 EPE29964.1 - 8.8e-40 136.6 0.0 1.7e-30 106.1 0.0 2.8 2 1 0 2 2 2 2 Subtilase family DUF1034 PF06280.7 EPE29964.1 - 2e-07 31.3 0.4 3.8e-07 30.5 0.3 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) MFS_1 PF07690.11 EPE29965.1 - 4.1e-39 134.2 60.6 2.4e-36 125.1 35.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE29965.1 - 0.0057 15.2 36.0 0.062 11.8 9.4 4.0 1 1 2 4 4 4 2 Sugar (and other) transporter PDR_assoc PF08370.6 EPE29965.1 - 9 5.8 10.4 0.3 10.6 1.5 2.9 4 0 0 4 4 4 0 Plant PDR ABC transporter associated TPR_MLP1_2 PF07926.7 EPE29967.1 - 0.011 15.5 24.6 0.011 15.5 17.0 3.9 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein TSC22 PF01166.13 EPE29967.1 - 0.042 13.7 1.4 0.042 13.7 1.0 4.4 3 2 1 5 5 5 0 TSC-22/dip/bun family SpoU_methylase PF00588.14 EPE29967.1 - 0.059 13.2 0.2 0.18 11.6 0.2 1.8 1 0 0 1 1 1 0 SpoU rRNA Methylase family ATP_bind_2 PF03668.10 EPE29967.1 - 0.35 9.8 4.4 0.16 10.9 1.2 1.8 1 1 0 1 1 1 0 P-loop ATPase protein family DUF2011 PF09428.5 EPE29968.1 - 1.4e-27 96.1 17.4 2.7e-27 95.2 12.1 1.4 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Peptidase_S49_N PF08496.5 EPE29968.1 - 8.5 6.1 9.9 14 5.4 6.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NDT80_PhoG PF05224.7 EPE29969.1 - 3.3e-29 102.2 0.0 5.5e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Methyltransf_26 PF13659.1 EPE29971.1 - 3.8e-12 46.2 0.0 7.7e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE29971.1 - 3.7e-10 39.5 0.0 2.7e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE29971.1 - 7.7e-08 32.8 0.0 2.4e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPE29971.1 - 1.7e-06 27.5 0.0 8.7e-05 21.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.11 EPE29971.1 - 4.1e-05 22.8 0.0 5.9e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.13 EPE29971.1 - 0.0019 17.7 0.0 0.031 13.8 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 EPE29971.1 - 0.0094 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE29971.1 - 0.063 13.7 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EPE29971.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EPE29971.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Suc_Fer-like PF06999.7 EPE29972.1 - 1.1e-49 169.5 0.0 1.3e-49 169.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF2823 PF11034.3 EPE29974.1 - 1.3e-32 111.6 11.1 1.5e-32 111.5 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) CtnDOT_TraJ PF07863.6 EPE29974.1 - 0.092 13.2 1.7 0.11 12.9 1.2 1.2 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon HSP9_HSP12 PF04119.7 EPE29974.1 - 0.81 9.8 4.3 3.1 7.9 2.6 1.9 1 1 1 2 2 2 0 Heat shock protein 9/12 EBP PF05241.7 EPE29975.1 - 3.9e-64 215.2 11.2 4.6e-64 215.0 7.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein Kei1 PF08552.6 EPE29975.1 - 0.1 12.2 3.4 0.22 11.1 2.3 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF788 PF05620.6 EPE29975.1 - 0.16 11.7 6.4 0.3 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) zf-RING_5 PF14634.1 EPE29976.1 - 3.2e-05 23.5 17.3 6.2e-05 22.6 12.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPE29976.1 - 9.8e-05 22.1 17.9 0.00021 21.0 12.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE29976.1 - 0.0001 22.2 16.6 0.00022 21.1 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EPE29976.1 - 0.0016 17.9 13.9 0.0037 16.8 9.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EPE29976.1 - 0.0044 16.7 6.4 0.0093 15.6 4.5 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 EPE29976.1 - 0.0076 15.8 17.4 0.018 14.6 12.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPE29976.1 - 0.16 11.7 10.1 0.42 10.3 6.9 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Thioredoxin_2 PF13098.1 EPE29977.1 - 0.12 12.5 0.4 0.35 11.0 0.3 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain zf-C3HC4_3 PF13920.1 EPE29977.1 - 0.14 11.8 2.7 0.23 11.1 1.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE29978.1 - 0.00051 19.8 9.0 0.00096 18.9 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE29978.1 - 0.00052 19.9 7.1 0.00052 19.9 4.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE29978.1 - 0.0019 17.8 5.6 0.0075 15.9 4.0 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE29978.1 - 0.0031 17.1 3.5 0.0032 17.0 1.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPE29978.1 - 0.026 14.2 2.0 0.062 13.0 1.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EPE29978.1 - 0.067 12.7 5.3 0.4 10.2 3.9 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Mit_ribos_Mrp51 PF11709.3 EPE29978.1 - 0.091 11.9 0.3 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit zf-C3HC4_3 PF13920.1 EPE29979.1 - 6.9e-06 25.6 4.2 1.8e-05 24.3 2.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE29979.1 - 1.4e-05 24.7 5.7 2.9e-05 23.7 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPE29979.1 - 5.1e-05 22.8 7.6 0.00011 21.8 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE29979.1 - 0.00033 20.3 5.6 0.00066 19.3 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.6 EPE29979.1 - 0.0004 20.1 1.7 0.00087 19.0 1.2 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.1 EPE29979.1 - 0.0011 18.9 7.7 0.0023 17.8 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPE29979.1 - 0.0023 17.5 2.3 0.0054 16.4 1.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EPE29979.1 - 0.0026 17.2 7.9 0.0026 17.2 5.5 2.2 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EPE29979.1 - 0.53 10.1 4.0 0.28 11.0 0.6 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EPE29979.1 - 0.66 9.9 8.9 1.6 8.7 6.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EPE29979.1 - 1.3 8.5 7.6 6 6.4 5.3 2.1 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger 7TM_GPCR_Srh PF10318.4 EPE29982.1 - 0.0019 17.0 6.4 0.0019 17.0 4.5 1.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srh adh_short PF00106.20 EPE29983.1 - 2.2e-24 86.2 0.3 4.4e-24 85.2 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE29983.1 - 4.6e-11 42.9 0.1 6.1e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EPE29983.1 - 2.1e-08 33.6 0.1 4.3e-07 29.3 0.1 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EPE29983.1 - 5.3e-07 29.4 0.2 9.5e-07 28.6 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPE29983.1 - 2.8e-05 24.1 0.1 4.7e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE29983.1 - 0.0027 16.9 0.1 0.0049 16.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.21 EPE29983.1 - 0.025 14.1 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPE29984.1 - 1.2e-49 167.8 0.0 2.3e-49 166.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPE29984.1 - 3.1e-15 55.8 0.0 4.7e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain HET PF06985.6 EPE29985.1 - 7.2e-24 84.5 0.9 6.1e-23 81.5 0.4 2.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CorA PF01544.13 EPE29986.1 - 2.4 7.1 8.4 7.2 5.5 5.7 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 EPE29987.1 - 5.5e-22 78.1 0.0 9.1e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE29987.1 - 1.1e-07 31.1 0.0 2.7e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3425 PF11905.3 EPE29988.1 - 3.1e-29 101.6 0.8 6.3e-29 100.5 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Glyco_hydro_3 PF00933.16 EPE29989.1 - 4.2e-85 285.3 0.0 5.9e-85 284.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE29989.1 - 1.9e-45 155.1 0.1 3.1e-45 154.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE29989.1 - 9.4e-23 79.9 0.0 2.1e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ketoacyl-synt PF00109.21 EPE29990.1 - 2e-78 263.4 0.0 3.4e-78 262.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPE29990.1 - 1.1e-41 143.2 0.0 1.8e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EPE29990.1 - 8.7e-33 112.6 0.1 2e-32 111.4 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EPE29990.1 - 1.1e-29 104.3 0.0 2.6e-29 103.0 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EPE29990.1 - 6.4e-20 71.1 10.5 1.3e-09 38.2 1.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EPE29990.1 - 3.1e-11 42.9 0.0 6.4e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 EPE29990.1 - 1.3e-07 31.6 0.2 0.00031 20.7 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE29990.1 - 1.8e-05 24.4 0.0 0.077 12.7 0.0 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EPE29990.1 - 0.00063 18.8 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.3 EPE29990.1 - 0.4 10.0 0.0 0.92 8.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) adh_short PF00106.20 EPE29991.1 - 2.6e-13 50.2 3.0 1e-11 45.0 2.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE29991.1 - 6.3e-12 45.7 0.0 3.7e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE29991.1 - 4e-07 29.8 0.1 6.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EPE29991.1 - 2.9e-05 24.1 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Acyl_transf_1 PF00698.16 EPE29992.1 - 6.9e-56 189.8 0.0 2.5e-54 184.7 0.0 2.5 3 0 0 3 3 3 1 Acyl transferase domain DUF1729 PF08354.5 EPE29992.1 - 7.8e-31 105.6 0.1 1.8e-30 104.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 EPE29992.1 - 4.6e-28 97.0 0.1 9.5e-28 96.0 0.1 1.5 1 0 0 1 1 1 1 MaoC like domain NMO PF03060.10 EPE29992.1 - 4.8e-09 35.8 0.0 3.7e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase MaoC_dehydrat_N PF13452.1 EPE29992.1 - 3.4e-08 33.3 0.0 3.1e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase ketoacyl-synt PF00109.21 EPE29993.1 - 3.8e-22 78.9 0.2 9.5e-22 77.6 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EPE29993.1 - 2.2e-19 70.1 0.0 5.7e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EPE29993.1 - 5.9e-13 48.6 0.0 1.2e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EPE29993.1 - 4e-11 42.7 0.0 1.8e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EPE29993.1 - 9.2e-07 28.6 0.2 3.5e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EPE29993.1 - 1.1e-06 28.6 0.1 9.5e-06 25.6 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.16 EPE29993.1 - 0.05 13.0 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 EPE29994.1 - 1.2e-41 142.6 53.0 1.2e-41 142.6 36.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE29994.1 - 3.1e-12 45.8 3.8 3.1e-12 45.8 2.7 3.4 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 EPE29994.1 - 1e-07 30.5 23.3 1.4e-07 30.1 16.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WTF PF03303.8 EPE29994.1 - 0.095 12.1 2.6 0.25 10.7 1.8 1.8 1 0 0 1 1 1 0 WTF protein DUF3169 PF11368.3 EPE29994.1 - 1.5 7.9 8.7 0.13 11.4 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) AflR PF08493.5 EPE29995.1 - 4e-16 58.8 3.9 6.6e-16 58.1 2.7 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EPE29995.1 - 3.6e-07 29.9 11.3 8.1e-07 28.8 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EPE29997.1 - 1.7e-18 66.8 0.1 1.9e-17 63.3 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE29997.1 - 3.4e-06 26.1 0.1 0.0041 16.0 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE29997.1 - 0.00022 21.1 0.0 0.00065 19.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPE29997.1 - 0.00081 19.7 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE29997.1 - 0.011 15.6 0.2 0.04 13.7 0.2 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE29997.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FSH1 PF03959.8 EPE29998.1 - 7.8e-27 94.1 0.0 5.7e-26 91.2 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EPE29998.1 - 7.9e-07 29.1 0.1 1e-06 28.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EPE29999.1 - 3.3e-13 49.4 0.0 1.7e-12 47.1 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPE29999.1 - 1.6e-06 27.9 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE29999.1 - 0.00025 20.9 0.0 0.00041 20.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EPE29999.1 - 0.017 14.3 0.0 0.082 12.0 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase p450 PF00067.17 EPE30000.1 - 3.7e-23 81.7 0.0 6.1e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2062 PF09835.4 EPE30000.1 - 0.049 13.2 0.1 0.15 11.6 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Methyltransf_2 PF00891.13 EPE30001.1 - 2.8e-33 115.1 0.0 3.9e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase YARHG PF13308.1 EPE30002.1 - 0.043 13.3 0.2 0.15 11.5 0.1 1.9 1 0 0 1 1 1 0 YARHG domain LRAT PF04970.8 EPE30003.1 - 0.11 12.3 0.2 0.2 11.5 0.1 1.5 1 1 0 1 1 1 0 Lecithin retinol acyltransferase HET PF06985.6 EPE30004.1 - 1.2e-33 116.1 0.2 1.8e-33 115.6 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4003 PF13170.1 EPE30004.1 - 0.22 10.7 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) PNTB PF02233.11 EPE30005.1 - 1.1e-162 542.0 21.5 1.1e-162 542.0 14.9 1.8 2 1 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EPE30005.1 - 2.2e-51 173.7 0.3 4.8e-51 172.6 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EPE30005.1 - 3.4e-46 156.6 0.1 9.4e-46 155.1 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EPE30005.1 - 9.9e-31 105.7 4.3 9.9e-31 105.7 3.0 4.0 5 0 0 5 5 4 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EPE30005.1 - 0.00085 18.5 0.1 1.2 8.2 0.0 2.9 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EPE30005.1 - 0.0055 16.2 0.1 0.027 13.9 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EPE30005.1 - 0.011 15.2 0.0 0.09 12.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox_2 PF07992.9 EPE30005.1 - 0.047 13.5 1.0 0.081 12.7 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF442 PF04273.8 EPE30005.1 - 0.049 13.4 0.1 7.4 6.4 0.1 2.7 2 0 0 2 2 2 0 Putative phosphatase (DUF442) TPP_enzyme_M PF00205.17 EPE30005.1 - 0.076 12.7 1.3 0.86 9.3 0.5 2.9 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Shikimate_DH PF01488.15 EPE30005.1 - 0.63 10.1 3.7 22 5.1 0.0 3.5 5 0 0 5 5 4 0 Shikimate / quinate 5-dehydrogenase PBP PF01161.15 EPE30006.1 - 9.7e-12 44.9 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SEEEED PF14797.1 EPE30007.1 - 0.31 11.1 3.1 0.42 10.7 2.1 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex RRN7 PF11781.3 EPE30008.1 - 1.5 8.4 4.3 18 4.9 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 FAD_binding_4 PF01565.18 EPE30009.1 - 4.4e-22 78.0 1.7 7.4e-22 77.3 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPE30009.1 - 4.2e-12 45.7 0.1 8e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like HA2 PF04408.18 EPE30010.1 - 4.1e-15 55.6 0.1 8.9e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPE30010.1 - 2.3e-12 46.6 0.0 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPE30010.1 - 1.4e-08 34.3 0.3 3.9e-08 32.9 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EPE30010.1 - 0.0023 17.7 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EPE30010.1 - 0.0032 17.5 0.0 0.013 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EPE30010.1 - 0.0034 16.3 0.1 0.0077 15.1 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EPE30010.1 - 0.041 13.3 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Nucleo_P87 PF07267.6 EPE30011.1 - 0.27 9.8 2.2 0.3 9.7 1.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GAS2 PF02187.12 EPE30012.1 - 0.00012 21.8 0.1 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Aconitase PF00330.15 EPE30013.1 - 2.5e-70 237.2 0.2 1.3e-45 155.7 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPE30013.1 - 4.4e-24 85.0 0.0 9.2e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain NAD_binding_4 PF07993.7 EPE30014.1 - 4.2e-37 127.4 0.0 1e-36 126.1 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EPE30014.1 - 4.3e-15 55.7 0.0 7.5e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EPE30014.1 - 2.2e-05 24.6 0.2 4.1e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EPE30014.1 - 5.9e-05 21.9 0.0 9.2e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPE30014.1 - 0.0032 17.5 0.0 0.0079 16.2 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EPE30014.1 - 0.0032 17.7 0.0 0.0087 16.3 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF604 PF04646.7 EPE30016.1 - 2.4e-06 26.9 0.0 6.5e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Fringe PF02434.11 EPE30016.1 - 3.4e-06 26.4 0.0 7.4e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Fringe-like AA_permease_2 PF13520.1 EPE30018.1 - 2.7e-45 154.7 38.7 1.9e-40 138.7 19.5 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 EPE30018.1 - 3.6e-07 28.8 37.6 6.4e-06 24.7 17.9 2.2 2 0 0 2 2 2 2 Amino acid permease GFA PF04828.9 EPE30019.1 - 1.4e-09 37.7 0.3 2.3e-07 30.6 0.2 2.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.11 EPE30019.1 - 0.07 13.0 0.2 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Abhydrolase_4 PF08386.5 EPE30020.1 - 1.9e-20 72.6 0.0 9.7e-20 70.3 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 EPE30020.1 - 4.3e-17 62.4 0.0 4.8e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE30020.1 - 7.5e-10 39.0 0.0 1e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE30020.1 - 0.00059 19.6 0.0 0.0069 16.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family APH PF01636.18 EPE30021.1 - 3.4e-11 43.3 0.0 7.2e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE30021.1 - 0.0004 20.0 0.0 0.0008 19.0 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Rax2 PF12768.2 EPE30022.1 - 0.036 13.2 0.0 1.6 7.8 0.0 2.7 3 0 0 3 3 3 0 Cortical protein marker for cell polarity DUF2919 PF11143.3 EPE30022.1 - 4.6 7.0 8.2 9.9 5.9 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2919) HET PF06985.6 EPE30023.1 - 7.9e-24 84.3 0.0 1.4e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TEP1_N PF05386.6 EPE30023.1 - 0.04 13.3 0.0 0.099 12.1 0.0 1.6 1 0 0 1 1 1 0 TEP1 N-terminal domain Peptidase_S41 PF03572.13 EPE30024.1 - 2.5e-11 43.2 0.0 1.1e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase family S41 Peptidase_S41 PF03572.13 EPE30025.1 - 1.2e-06 28.1 0.0 6.9e-06 25.5 0.0 2.2 2 1 0 2 2 2 1 Peptidase family S41 Aminotran_1_2 PF00155.16 EPE30027.1 - 2.3e-84 283.4 0.0 3e-84 283.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPE30027.1 - 3.5e-07 29.2 0.0 6.7e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EPE30027.1 - 1.7e-05 23.2 0.0 3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EPE30027.1 - 0.0048 15.9 0.8 0.008 15.2 0.6 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3405 PF11885.3 EPE30027.1 - 0.079 11.1 0.1 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Actin PF00022.14 EPE30028.1 - 1.1e-21 76.7 0.0 2.4e-09 36.0 0.0 3.4 3 1 0 3 3 3 3 Actin MreB_Mbl PF06723.8 EPE30028.1 - 0.0035 15.9 0.0 0.17 10.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein AAA PF00004.24 EPE30030.1 - 6.9e-21 74.8 0.0 1.7e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE30030.1 - 0.0053 16.7 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE30030.1 - 0.0082 16.2 0.1 0.054 13.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EPE30030.1 - 0.011 15.4 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPE30030.1 - 0.017 15.9 0.0 0.017 15.9 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EPE30030.1 - 0.098 12.9 0.0 0.098 12.9 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.1 EPE30030.1 - 0.13 11.9 0.2 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain Peptidase_C14 PF00656.17 EPE30031.1 - 0.0046 16.6 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Caspase domain CLASP_N PF12348.3 EPE30031.1 - 0.1 11.9 0.1 0.31 10.3 0.1 1.7 2 0 0 2 2 2 0 CLASP N terminal DUF4652 PF15525.1 EPE30031.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) MoaC PF01967.16 EPE30032.1 - 1.8e-49 166.9 4.3 2.1e-26 92.1 0.2 2.2 2 0 0 2 2 2 2 MoaC family Mob_synth_C PF06463.8 EPE30033.1 - 7e-34 116.2 0.0 3.9e-33 113.8 0.0 2.0 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EPE30033.1 - 4.1e-20 72.6 0.1 2.1e-19 70.3 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 EPE30033.1 - 0.00016 21.6 0.0 0.00084 19.3 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EPE30033.1 - 0.00022 21.3 0.0 0.00062 19.9 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain IKI3 PF04762.7 EPE30034.1 - 0.047 11.4 1.2 3.3 5.4 0.0 2.9 2 1 0 3 3 3 0 IKI3 family Methyltransf_18 PF12847.2 EPE30035.1 - 1.4e-11 44.9 0.0 2.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPE30035.1 - 1.1e-05 25.1 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EPE30035.1 - 3e-05 23.7 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE30035.1 - 0.00052 19.6 0.0 0.00082 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE30035.1 - 0.0011 19.2 0.0 0.0024 18.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE30035.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.5 EPE30035.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MetW PF07021.7 EPE30035.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 EPE30035.1 - 0.038 14.8 0.0 0.067 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EPE30035.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EPE30035.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PDEase_I PF00233.14 EPE30036.1 - 2.2e-48 165.0 0.2 1.6e-44 152.4 0.0 2.1 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase DUF2589 PF11655.3 EPE30037.1 - 0.0031 17.6 6.6 0.52 10.4 0.3 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2589) DUF1798 PF08807.5 EPE30037.1 - 0.54 9.9 3.2 1.6 8.4 2.2 1.8 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Abhydrolase_3 PF07859.8 EPE30038.1 - 1.5e-36 125.9 0.0 2e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EPE30038.1 - 0.04 12.6 0.0 0.066 11.9 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Peptidase_S9 PF00326.16 EPE30038.1 - 0.095 11.8 0.0 0.28 10.3 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF39 PF01837.11 EPE30038.1 - 0.19 10.3 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF39 STE3 PF02076.10 EPE30040.1 - 1.9e-59 201.0 15.0 2.3e-59 200.7 10.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF3328 PF11807.3 EPE30042.1 - 2.8e-45 154.6 0.0 3.1e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TPR_12 PF13424.1 EPE30043.1 - 5.4e-07 29.4 0.1 0.0088 15.9 0.0 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPE30043.1 - 0.00033 20.9 0.0 0.084 13.2 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EPE30043.1 - 0.006 16.4 0.2 12 5.9 0.0 3.8 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPE30043.1 - 0.047 13.6 0.3 15 5.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPE30043.1 - 0.18 12.2 0.4 8.9 7.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.2 EPE30044.1 - 1.5e-35 121.3 0.5 4.6e-20 71.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE30044.1 - 3.3e-22 77.1 0.3 6.8e-07 28.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EPE30044.1 - 8.2e-14 51.6 0.1 1.4e-07 31.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE30044.1 - 2.2e-13 49.9 0.3 3.3e-09 36.6 0.1 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE30044.1 - 1.4e-11 43.4 0.1 0.022 14.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Abhydrolase_5 PF12695.2 EPE30045.1 - 4.2e-08 33.0 0.1 1.8e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE30045.1 - 2.7e-06 27.4 0.1 3.9e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EPE30045.1 - 3.5e-05 23.1 0.1 0.00017 20.9 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF1100 PF06500.6 EPE30045.1 - 0.01 14.4 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.6 EPE30045.1 - 0.01 15.5 0.1 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 EPE30045.1 - 0.012 14.0 0.2 0.022 13.2 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) adh_short PF00106.20 EPE30046.1 - 4e-22 78.9 0.0 5.5e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE30046.1 - 6.1e-07 29.4 0.0 8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE30046.1 - 3.1e-05 23.7 0.0 5.9e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE30046.1 - 0.00017 21.1 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EPE30046.1 - 0.0055 15.7 0.1 0.0083 15.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EPE30046.1 - 0.045 13.7 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NACHT PF05729.7 EPE30047.1 - 0.0065 16.1 0.0 0.12 11.9 0.0 2.5 1 1 0 1 1 1 1 NACHT domain AF0941-like PF14591.1 EPE30047.1 - 0.049 13.6 1.4 0.13 12.3 0.2 2.3 2 0 0 2 2 2 0 AF0941-like AAA_16 PF13191.1 EPE30047.1 - 0.06 13.3 0.0 0.66 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EPE30047.1 - 0.07 13.0 0.1 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EPE30047.1 - 0.13 12.5 0.6 0.89 9.8 0.0 2.6 3 0 0 3 3 3 0 ABC transporter adh_short PF00106.20 EPE30048.1 - 9.6e-05 22.3 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE30048.1 - 0.0008 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 KR domain SHP PF03579.8 EPE30049.1 - 0.029 13.7 3.1 0.044 13.1 0.7 2.2 2 0 0 2 2 2 0 Small hydrophobic protein His_Phos_2 PF00328.17 EPE30050.1 - 4e-28 98.7 0.0 4.9e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EPE30050.1 - 0.00027 21.0 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pept_tRNA_hydro PF01195.14 EPE30051.1 - 6.3e-38 130.0 0.0 7.9e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase BAR PF03114.13 EPE30052.1 - 2e-62 210.7 4.8 2.4e-62 210.4 3.3 1.1 1 0 0 1 1 1 1 BAR domain FliD_N PF02465.13 EPE30052.1 - 0.53 10.6 3.1 7 7.0 0.2 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus KAR9 PF08580.5 EPE30053.1 - 0.88 7.7 5.4 0.97 7.6 3.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 MTTB PF06253.6 EPE30055.1 - 0.037 11.7 0.1 0.046 11.4 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Glycos_transf_1 PF00534.15 EPE30056.1 - 4.3e-24 84.8 0.0 7.5e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPE30056.1 - 1.4e-10 41.4 0.0 3.4e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EPE30056.1 - 2.5e-10 40.3 0.1 6.8e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EPE30056.1 - 2.6e-08 33.9 0.0 6.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EPE30056.1 - 2.9e-08 34.0 0.3 7.5e-08 32.6 0.2 1.7 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain GDE_C PF06202.9 EPE30057.1 - 0.045 12.4 0.1 0.31 9.6 0.0 2.2 2 1 0 2 2 2 0 Amylo-alpha-1,6-glucosidase Mito_carr PF00153.22 EPE30058.1 - 6.5e-47 157.1 0.7 2e-16 59.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.7 EPE30059.1 - 7.7e-29 99.6 1.4 7.7e-29 99.6 1.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE30059.1 - 5.7e-07 29.1 0.0 0.00098 18.6 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EPE30059.1 - 0.018 14.7 0.1 0.05 13.2 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Methyltransf_18 PF12847.2 EPE30059.1 - 0.092 13.3 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EPE30059.1 - 0.1 11.7 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EPE30059.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF2306 PF10067.4 EPE30060.1 - 5.1e-14 52.2 6.0 5.1e-14 52.2 4.2 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF4118 PF13493.1 EPE30061.1 - 0.14 12.3 2.9 0.27 11.4 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4118) GMC_oxred_C PF05199.8 EPE30063.1 - 2.7e-09 37.4 0.8 1.8e-08 34.8 0.1 2.6 3 0 0 3 3 3 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EPE30063.1 - 3.3e-06 26.4 0.0 3.3e-05 23.2 0.0 2.5 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EPE30063.1 - 0.00022 20.2 0.0 0.00034 19.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EPE30063.1 - 0.0096 15.9 0.4 0.038 14.0 0.3 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain adh_short PF00106.20 EPE30065.1 - 7.5e-17 61.7 0.0 1e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE30065.1 - 4.2e-06 26.6 0.0 5.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE30065.1 - 5.2e-06 26.2 0.0 7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE30065.1 - 0.00026 20.5 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPE30065.1 - 0.0011 18.7 0.3 0.002 17.8 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EPE30065.1 - 0.0016 18.4 0.5 0.02 14.9 0.2 2.3 2 1 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 EPE30065.1 - 0.016 15.3 1.5 0.12 12.5 0.4 2.5 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EPE30065.1 - 0.036 13.7 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_4 PF13439.1 EPE30065.1 - 0.094 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ROF PF07073.7 EPE30065.1 - 0.17 11.8 0.1 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) Rox3 PF08633.5 EPE30066.1 - 9e-45 153.3 1.1 9e-45 153.3 0.7 2.0 2 1 0 2 2 2 1 Rox3 mediator complex subunit RRM_1 PF00076.17 EPE30067.1 - 6.7e-60 198.6 0.0 2.5e-19 68.6 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE30067.1 - 1.1e-39 134.2 1.1 1.2e-10 41.2 0.0 5.8 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE30067.1 - 3.1e-23 81.3 0.3 5.9e-07 29.2 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 EPE30067.1 - 0.018 14.3 0.0 0.67 9.3 0.0 2.8 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated SGT1 PF07093.6 EPE30067.1 - 0.12 10.6 17.9 0.21 9.9 12.4 1.3 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.7 EPE30067.1 - 0.97 7.2 36.8 0.052 11.4 19.5 2.5 3 0 0 3 3 3 0 Nop14-like family Gln-synt_C PF00120.19 EPE30068.1 - 0.13 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain PRY PF13765.1 EPE30073.1 - 0.091 12.3 1.1 1.4 8.4 0.1 2.1 2 0 0 2 2 2 0 SPRY-associated domain Med5 PF08689.5 EPE30074.1 - 8.3e-97 325.0 0.0 1e-96 324.7 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 Involucrin_N PF10583.4 EPE30076.1 - 0.028 14.7 1.8 0.036 14.3 1.3 1.2 1 0 0 1 1 1 0 Involucrin of squamous epithelia N-terminus POM121 PF15229.1 EPE30076.1 - 0.091 12.1 1.0 0.093 12.1 0.7 1.0 1 0 0 1 1 1 0 POM121 family FTZ PF03867.9 EPE30076.1 - 0.11 11.7 2.5 0.11 11.6 1.8 1.0 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region 1-cysPrx_C PF10417.4 EPE30076.1 - 0.39 10.4 2.0 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin DUF2076 PF09849.4 EPE30078.1 - 0.051 13.6 1.3 0.051 13.6 0.9 2.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Acetyltransf_1 PF00583.19 EPE30079.1 - 9.9e-09 35.1 0.0 2.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE30079.1 - 0.00018 21.6 0.0 0.00048 20.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE30079.1 - 0.00052 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPE30079.1 - 0.0015 18.6 0.0 0.009 16.1 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3528 PF12045.3 EPE30079.1 - 0.0035 17.4 0.0 0.0059 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) EHN PF06441.7 EPE30080.1 - 2.9e-37 127.0 0.6 4.1e-37 126.5 0.4 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EPE30080.1 - 1.8e-15 57.4 1.8 2.8e-15 56.8 0.6 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE30080.1 - 2.9e-06 27.0 0.1 5.8e-06 26.0 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Amidase PF01425.16 EPE30081.1 - 4.1e-85 286.2 0.2 5.6e-85 285.8 0.2 1.1 1 0 0 1 1 1 1 Amidase FAD_binding_2 PF00890.19 EPE30082.1 - 2e-121 405.7 6.0 2.7e-121 405.3 4.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EPE30082.1 - 5.6e-38 129.7 0.2 8.5e-38 129.1 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EPE30082.1 - 3e-06 27.2 1.3 0.00024 21.0 0.9 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPE30082.1 - 4.3e-06 25.8 1.4 2.5e-05 23.3 1.0 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 EPE30082.1 - 0.00021 20.3 0.8 0.0023 16.9 0.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPE30082.1 - 0.00035 19.7 2.0 0.036 13.1 0.5 2.7 2 1 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 EPE30082.1 - 0.0045 16.0 0.4 0.0072 15.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EPE30082.1 - 0.048 12.1 0.5 0.12 10.8 0.4 1.6 1 0 0 1 1 1 0 HI0933-like protein ELFV_dehydrog PF00208.16 EPE30083.1 - 1.2e-86 290.2 5.2 1.5e-86 289.9 3.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EPE30083.1 - 2.1e-48 163.2 0.0 7.6e-48 161.3 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EPE30083.1 - 0.0069 16.6 0.1 0.017 15.4 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EPE30083.1 - 0.082 12.4 0.2 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EPE30083.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 EPE30084.1 - 6.9e-47 159.6 0.0 8.6e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SDH_sah PF01972.11 EPE30085.1 - 0.013 14.3 1.2 0.024 13.4 0.9 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DUF2894 PF11445.3 EPE30085.1 - 0.034 14.3 11.0 0.048 13.9 6.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) FUSC PF04632.7 EPE30085.1 - 2.6 6.3 5.0 2.3 6.5 2.8 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF1510 PF07423.6 EPE30085.1 - 8.3 5.7 23.6 0.29 10.4 8.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) GLE1 PF07817.8 EPE30087.1 - 5.1e-22 78.0 0.0 8.2e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein Aminotran_4 PF01063.14 EPE30087.1 - 0.13 11.7 0.2 0.25 10.7 0.2 1.5 1 0 0 1 1 1 0 Aminotransferase class IV SMN PF06003.7 EPE30087.1 - 2.4 7.1 14.9 4 6.4 10.3 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RNB PF00773.14 EPE30088.1 - 1.3e-85 287.5 0.0 2.6e-85 286.5 0.0 1.5 1 0 0 1 1 1 1 RNB domain AAA_7 PF12775.2 EPE30088.1 - 0.092 11.8 0.1 1.8 7.5 0.0 2.2 1 1 1 2 2 2 0 P-loop containing dynein motor region D3 DUF4239 PF14023.1 EPE30088.1 - 0.39 10.0 0.2 0.81 9.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Ferritin_2 PF13668.1 EPE30089.1 - 2.8e-40 137.4 0.4 4.3e-40 136.8 0.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain adh_short PF00106.20 EPE30090.1 - 4.5e-12 46.1 0.1 7.2e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE30090.1 - 9.3e-05 22.1 0.1 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE30090.1 - 0.00027 20.7 0.0 0.00036 20.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MCPsignal PF00015.16 EPE30090.1 - 0.06 12.8 0.1 0.093 12.2 0.1 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Ecl1 PF12855.2 EPE30091.1 - 0.0037 16.5 0.5 0.0083 15.4 0.4 1.5 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EPE30091.1 - 0.19 11.6 2.0 0.44 10.4 1.4 1.5 1 0 0 1 1 1 0 MYND finger DHO_dh PF01180.16 EPE30092.1 - 5.6e-15 55.0 0.0 7.9e-15 54.5 0.0 1.3 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 EPE30092.1 - 0.34 10.0 7.9 0.15 11.1 3.2 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase ABC_tran PF00005.22 EPE30093.1 - 2.2e-48 164.0 0.0 5.6e-26 91.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPE30093.1 - 3.4e-33 115.2 31.0 5.1e-31 108.1 6.2 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EPE30093.1 - 1.9e-12 47.7 1.0 0.074 13.0 0.0 4.5 3 1 1 4 4 4 4 AAA domain AAA_16 PF13191.1 EPE30093.1 - 1.3e-11 44.8 0.0 2e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EPE30093.1 - 7.8e-09 35.7 0.0 0.00068 19.7 0.0 3.2 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EPE30093.1 - 4.3e-07 29.3 6.1 0.026 13.7 1.2 4.5 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPE30093.1 - 4.4e-07 29.3 0.1 0.01 15.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPE30093.1 - 2.8e-06 26.5 0.0 0.018 14.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EPE30093.1 - 7e-06 26.5 0.0 0.071 13.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_14 PF13173.1 EPE30093.1 - 7.2e-06 25.9 0.0 0.0024 17.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EPE30093.1 - 1.9e-05 24.4 0.0 0.0018 18.0 0.0 2.8 2 0 0 2 2 2 1 Archaeal ATPase AAA_25 PF13481.1 EPE30093.1 - 2e-05 24.0 0.2 0.35 10.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 EPE30093.1 - 3.9e-05 23.7 0.1 0.06 13.5 0.0 2.8 3 0 0 3 3 2 1 RNA helicase ATP-synt_ab PF00006.20 EPE30093.1 - 4.6e-05 23.0 0.1 0.011 15.2 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 EPE30093.1 - 6.4e-05 23.7 0.3 0.28 12.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EPE30093.1 - 0.00013 21.8 0.0 0.43 10.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EPE30093.1 - 0.00013 22.2 0.0 0.2 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EPE30093.1 - 0.00019 21.0 0.2 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_33 PF13671.1 EPE30093.1 - 0.00022 21.1 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPE30093.1 - 0.00043 20.4 0.1 0.15 12.3 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EPE30093.1 - 0.00067 19.3 0.2 0.059 13.0 0.0 3.0 2 1 1 3 3 3 1 NACHT domain Adeno_IVa2 PF02456.10 EPE30093.1 - 0.0007 18.3 0.1 0.57 8.7 0.0 2.3 2 0 0 2 2 2 2 Adenovirus IVa2 protein AAA_23 PF13476.1 EPE30093.1 - 0.00077 19.8 0.1 0.14 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPE30093.1 - 0.0035 17.0 0.6 3 7.5 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EPE30093.1 - 0.0051 16.5 0.1 6.8 6.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RVP_2 PF08284.6 EPE30093.1 - 0.0051 16.7 0.2 0.02 14.8 0.1 2.0 2 0 0 2 2 1 1 Retroviral aspartyl protease AAA_24 PF13479.1 EPE30093.1 - 0.0061 16.1 0.1 1 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EPE30093.1 - 0.018 13.8 0.9 1.5 7.5 0.0 3.2 3 1 0 3 3 3 0 NB-ARC domain cobW PF02492.14 EPE30093.1 - 0.027 13.9 0.2 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EPE30093.1 - 0.032 13.2 0.1 3.8 6.4 0.0 2.6 3 0 0 3 3 2 0 Septin FtsK_SpoIIIE PF01580.13 EPE30093.1 - 0.032 13.6 0.1 0.51 9.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 EPE30093.1 - 0.035 13.6 0.0 5.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EPE30093.1 - 0.043 13.5 0.1 11 5.7 0.0 2.6 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 EPE30093.1 - 0.054 12.3 0.0 11 4.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 EPE30093.1 - 0.055 13.0 0.0 0.65 9.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 EPE30093.1 - 0.093 12.5 0.0 8 6.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family ABC_ATPase PF09818.4 EPE30093.1 - 0.11 11.0 1.5 0.78 8.2 0.0 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_PrkA PF08298.6 EPE30093.1 - 0.12 11.0 0.0 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain PRK PF00485.13 EPE30093.1 - 0.14 11.7 0.4 0.46 10.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 EPE30093.1 - 0.23 10.0 0.4 0.65 8.6 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Guanylate_kin PF00625.16 EPE30093.1 - 0.25 10.7 0.0 1 8.7 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase Zeta_toxin PF06414.7 EPE30093.1 - 0.34 9.9 0.0 9.8 5.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.1 EPE30093.1 - 0.74 8.7 0.0 6 5.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.1 EPE30093.1 - 0.85 9.5 3.7 0.71 9.8 0.2 2.6 3 1 0 3 3 1 0 Putative exonuclease SbcCD, C subunit TauD PF02668.11 EPE30094.1 - 3.1e-49 167.9 0.3 3.6e-49 167.7 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family BRCT PF00533.21 EPE30096.1 - 1.7e-11 44.0 0.0 5.5e-11 42.4 0.0 1.9 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPE30096.1 - 0.00024 20.8 0.0 0.00055 19.7 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain Nucleoplasmin PF03066.10 EPE30096.1 - 0.45 10.0 12.1 0.032 13.7 4.9 1.7 2 0 0 2 2 2 0 Nucleoplasmin DUF2890 PF11081.3 EPE30096.1 - 0.52 10.3 19.1 1.2 9.1 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) DUF4604 PF15377.1 EPE30096.1 - 0.94 9.6 22.0 1.6 8.9 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Tim54 PF11711.3 EPE30096.1 - 7.9 4.9 14.7 1.3 7.5 2.9 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 MFS_1 PF07690.11 EPE30099.1 - 1.5e-35 122.5 32.5 4.4e-34 117.7 23.3 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily FMN_dh PF01070.13 EPE30100.1 - 8.3e-113 376.8 0.0 1.1e-112 376.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EPE30100.1 - 5.6e-19 67.7 0.0 1.1e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EPE30100.1 - 0.00014 20.8 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EPE30100.1 - 0.0069 15.5 0.0 0.016 14.3 0.0 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase DGF-1_5 PF11038.3 EPE30100.1 - 0.0071 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 IMPDH PF00478.20 EPE30100.1 - 0.025 13.4 1.2 0.24 10.2 0.3 2.4 2 1 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain ABC_tran PF00005.22 EPE30102.1 - 1.3e-24 87.0 0.0 2.4e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPE30102.1 - 0.00065 19.7 0.0 0.017 15.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPE30102.1 - 0.0011 18.4 0.0 0.035 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EPE30102.1 - 0.006 15.7 0.2 0.011 14.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EPE30102.1 - 0.053 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPE30102.1 - 0.061 13.1 0.3 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Dynamin family SbcCD_C PF13558.1 EPE30102.1 - 0.077 12.9 0.1 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EPE30102.1 - 0.21 11.0 0.4 0.45 9.9 0.3 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TILa PF12714.2 EPE30102.1 - 5.4 6.8 8.7 2.2 8.1 0.6 3.2 1 1 2 3 3 3 0 TILa domain Fungal_trans PF04082.13 EPE30104.1 - 7.4e-10 38.1 1.7 2.2e-09 36.6 1.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE30104.1 - 1.9e-06 27.6 11.2 3e-06 27.0 7.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_2 PF03446.10 EPE30105.1 - 1.5e-72 242.7 10.1 1.4e-37 129.0 1.5 2.8 3 0 0 3 3 3 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EPE30105.1 - 2.2e-65 218.1 2.9 7.2e-34 116.4 0.2 2.7 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF1537 PF07005.6 EPE30105.1 - 4.7e-24 85.3 3.8 4.7e-24 85.3 2.6 2.8 3 0 0 3 3 3 1 Protein of unknown function, DUF1537 F420_oxidored PF03807.12 EPE30105.1 - 1.4e-12 47.8 3.5 1.2e-05 25.6 0.2 4.0 3 1 1 4 4 4 2 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EPE30105.1 - 1.1e-11 44.7 4.4 2.3e-05 24.1 0.0 2.8 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPE30105.1 - 1.6e-11 43.7 0.0 0.00017 20.8 0.0 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EPE30105.1 - 2.4e-08 33.5 6.5 0.052 12.9 0.0 4.6 3 2 1 5 5 5 3 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EPE30105.1 - 6.2e-06 26.3 0.0 0.27 11.3 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain POR PF01558.13 EPE30105.1 - 7.7e-05 22.6 5.3 0.003 17.4 0.1 3.8 3 1 0 3 3 3 1 Pyruvate ferredoxin/flavodoxin oxidoreductase IlvN PF07991.7 EPE30105.1 - 0.00058 19.2 0.2 0.59 9.4 0.0 2.5 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 EPE30105.1 - 0.00069 19.0 0.6 1.1 8.6 0.0 2.9 2 1 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Methyltransf_18 PF12847.2 EPE30105.1 - 0.003 18.1 0.0 1 9.9 0.0 3.4 4 0 0 4 4 4 1 Methyltransferase domain TrkA_N PF02254.13 EPE30105.1 - 0.003 17.5 0.1 7 6.6 0.0 3.7 3 0 0 3 3 3 1 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EPE30105.1 - 0.0036 17.0 1.4 3.2 7.4 0.0 3.9 2 2 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glu_syn_central PF04898.9 EPE30105.1 - 0.031 13.5 0.1 0.069 12.3 0.1 1.5 1 0 0 1 1 1 0 Glutamate synthase central domain Methyltransf_23 PF13489.1 EPE30105.1 - 0.14 11.8 0.0 6.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Ank_2 PF12796.2 EPE30107.1 - 3.1e-110 360.7 7.7 6.5e-25 87.2 0.0 6.6 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EPE30107.1 - 3.8e-89 288.3 5.7 1.8e-09 36.9 0.0 13.7 13 1 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.1 EPE30107.1 - 1.6e-65 215.6 16.0 2.5e-11 43.4 0.4 10.4 5 3 5 10 10 10 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE30107.1 - 6.1e-62 204.9 9.7 2.5e-13 50.1 0.3 9.4 5 1 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE30107.1 - 1.4e-57 185.8 0.6 1.3e-06 28.0 0.0 12.9 13 0 0 13 13 13 9 Ankyrin repeat NACHT PF05729.7 EPE30107.1 - 3.8e-10 39.6 0.0 3.8e-10 39.6 0.0 2.1 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EPE30107.1 - 0.00022 21.3 1.1 0.0011 19.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain Glyco_transf_90 PF05686.7 EPE30108.1 - 1.4e-13 50.2 2.4 2.2e-11 43.0 0.3 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 CAP59_mtransfer PF11735.3 EPE30110.1 - 7.3e-81 270.9 0.0 9.6e-81 270.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF2674 PF10879.3 EPE30110.1 - 0.021 14.5 0.1 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2674) Pectinesterase PF01095.14 EPE30112.1 - 2.9e-36 124.5 3.3 4.2e-36 124.0 2.3 1.1 1 0 0 1 1 1 1 Pectinesterase ERG4_ERG24 PF01222.12 EPE30115.1 - 2.6e-129 431.5 22.6 3.3e-129 431.2 15.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Xan_ur_permease PF00860.15 EPE30116.1 - 1.7e-52 178.1 29.8 6.7e-52 176.2 20.6 1.8 1 1 0 1 1 1 1 Permease family Amidohydro_1 PF01979.15 EPE30117.1 - 6.4e-51 173.9 1.8 8.6e-51 173.5 1.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EPE30117.1 - 2.4e-19 70.4 1.1 3.2e-18 66.7 0.8 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPE30117.1 - 3.8e-14 52.7 0.7 2.6e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EPE30117.1 - 8.4e-13 47.9 0.0 2.1e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EPE30117.1 - 0.0016 17.4 0.1 0.0033 16.3 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase DisA_N PF02457.11 EPE30117.1 - 0.016 14.3 0.0 0.053 12.6 0.0 1.9 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding TRAP_alpha PF03896.11 EPE30118.1 - 0.00018 20.5 0.0 0.0032 16.5 0.0 2.1 2 0 0 2 2 2 2 Translocon-associated protein (TRAP), alpha subunit 2OG-FeII_Oxy PF03171.15 EPE30119.1 - 1e-15 57.7 0.0 2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EPE30119.1 - 4.6e-13 49.7 0.0 8.3e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_transf_90 PF05686.7 EPE30120.1 - 1.4e-11 43.7 0.0 1.6e-08 33.6 0.0 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 90 Fungal_trans PF04082.13 EPE30121.1 - 1.9e-13 49.9 0.0 4.6e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain OTT_1508_deam PF14441.1 EPE30121.1 - 4.1e-13 49.3 0.0 1.1e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase DPPIV_N PF00930.16 EPE30122.1 - 2.2e-107 358.6 2.7 3.2e-107 358.1 1.9 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EPE30122.1 - 1.4e-42 145.3 4.3 3.3e-42 144.1 2.3 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE30122.1 - 2.1e-08 34.0 0.1 7.2e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EPE30122.1 - 4.8e-07 29.4 0.3 8.5e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EPE30122.1 - 3.7e-06 26.9 0.0 6.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EPE30122.1 - 7.4e-05 22.4 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EPE30122.1 - 0.0025 17.2 0.2 0.0054 16.1 0.2 1.5 1 0 0 1 1 1 1 Putative esterase PD40 PF07676.7 EPE30122.1 - 2.6 7.7 5.3 9.3 6.0 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat p450 PF00067.17 EPE30125.1 - 1.3e-46 159.1 0.0 1.5e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sas10 PF09368.5 EPE30126.1 - 5.1e-29 100.2 9.4 5.1e-29 100.2 6.5 2.2 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EPE30126.1 - 1.9e-11 43.9 0.1 6e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Glyco_hydro_18 PF00704.23 EPE30127.1 - 2.9e-57 194.6 0.0 4e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EPE30127.1 - 7.1e-18 64.3 145.4 9.9e-08 31.8 5.1 7.2 6 1 1 7 7 7 5 Chitin recognition protein FMN_dh PF01070.13 EPE30128.1 - 1.8e-109 365.9 0.0 2e-109 365.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EPE30128.1 - 0.00043 19.2 0.2 0.00064 18.7 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EPE30128.1 - 0.015 14.2 0.2 0.021 13.7 0.1 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase His_biosynth PF00977.16 EPE30128.1 - 0.03 13.6 0.2 0.88 8.7 0.1 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein HET PF06985.6 EPE30129.1 - 2.4e-19 69.8 0.1 5.4e-19 68.7 0.1 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.9 EPE30131.1 - 1.8e-52 178.3 1.5 2e-52 178.1 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DAO PF01266.19 EPE30132.1 - 4.2e-53 180.5 0.1 4.9e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPE30132.1 - 0.00032 20.8 0.0 0.076 13.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE30132.1 - 0.0033 17.3 0.2 0.0085 16.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE30132.1 - 0.025 14.4 0.0 0.051 13.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE30132.1 - 0.11 11.3 1.2 0.19 10.5 0.8 1.4 1 0 0 1 1 1 0 FAD binding domain SNF2_N PF00176.18 EPE30134.1 - 4.5e-41 140.6 0.0 6.1e-25 87.6 0.1 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE30134.1 - 4.6e-12 45.6 0.0 1.2e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EPE30134.1 - 0.00064 19.3 7.8 0.0015 18.2 5.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPE30134.1 - 0.14 11.9 7.3 0.31 10.9 5.1 1.6 1 0 0 1 1 1 0 Ring finger domain NACHT PF05729.7 EPE30135.1 - 1.1e-08 34.8 0.0 2.3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain zf-H2C2_2 PF13465.1 EPE30135.1 - 8.6e-07 28.9 16.5 2.3e-05 24.4 0.3 4.8 4 0 0 4 4 4 2 Zinc-finger double domain AAA_22 PF13401.1 EPE30135.1 - 0.00011 22.3 0.3 0.00091 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPE30135.1 - 0.00057 19.9 0.5 0.0061 16.5 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 EPE30135.1 - 0.0027 17.9 0.0 0.0095 16.1 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EPE30135.1 - 0.0063 15.5 0.0 0.015 14.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) zf-C2H2 PF00096.21 EPE30135.1 - 0.0073 16.5 2.2 0.0073 16.5 1.5 5.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE30135.1 - 0.011 15.9 1.7 0.011 15.9 1.2 6.1 5 0 0 5 5 5 0 C2H2-type zinc finger AAA_14 PF13173.1 EPE30135.1 - 0.018 14.9 0.0 0.1 12.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EPE30135.1 - 0.04 13.4 0.0 0.098 12.1 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase GvpL_GvpF PF06386.6 EPE30135.1 - 0.066 12.7 3.0 0.13 11.8 2.1 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF AAA_25 PF13481.1 EPE30135.1 - 0.1 11.9 0.0 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EPE30135.1 - 0.17 12.7 1.6 3.4 8.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain Zn-ribbon_8 PF09723.5 EPE30135.1 - 0.38 10.7 3.3 1.7 8.6 0.6 2.7 2 0 0 2 2 2 0 Zinc ribbon domain APH PF01636.18 EPE30136.1 - 2.2e-09 37.4 0.0 4.7e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EPE30136.1 - 0.0012 17.5 0.0 0.0016 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EPE30136.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sterol-sensing PF12349.3 EPE30138.1 - 1.1e-35 122.3 5.1 2.3e-35 121.3 3.6 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EPE30138.1 - 3.8e-07 28.4 5.3 5.4e-07 27.9 3.7 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 EPE30138.1 - 8.4e-06 25.4 2.3 0.14 12.1 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat MMPL PF03176.10 EPE30138.1 - 0.0063 15.2 1.1 0.014 14.1 0.7 1.6 1 0 0 1 1 1 1 MMPL family UK PF02512.9 EPE30139.1 - 0.17 12.3 0.3 1.2 9.6 0.1 2.0 2 0 0 2 2 2 0 Virulence determinant ketoacyl-synt PF00109.21 EPE30140.1 - 2e-68 230.6 0.0 3.4e-68 229.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPE30140.1 - 4.7e-66 223.2 0.0 8.8e-66 222.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EPE30140.1 - 2.3e-60 204.2 0.0 3.6e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EPE30140.1 - 7e-57 192.0 0.3 1.9e-56 190.6 0.1 1.8 2 0 0 2 2 1 1 KR domain adh_short PF00106.20 EPE30140.1 - 7e-42 143.1 0.8 2.2e-41 141.5 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPE30140.1 - 9.1e-33 112.6 0.1 1.9e-32 111.5 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EPE30140.1 - 2.5e-17 63.1 0.0 7.2e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EPE30140.1 - 5e-15 55.1 0.0 1.3e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE30140.1 - 1.3e-13 51.9 0.0 1.1e-12 48.9 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EPE30140.1 - 5.7e-13 48.8 0.0 5.3e-12 45.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 EPE30140.1 - 1.1e-07 31.6 0.2 3.6e-07 29.8 0.2 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.1 EPE30140.1 - 2.2e-07 30.5 0.0 5.1e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE30140.1 - 5.5e-06 26.7 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE30140.1 - 9.2e-06 26.2 0.0 4.7e-05 23.9 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EPE30140.1 - 0.00064 19.9 0.1 0.0017 18.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 EPE30140.1 - 0.034 14.5 0.0 0.092 13.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EPE30140.1 - 0.053 12.9 0.0 0.37 10.2 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase DREV PF05219.7 EPE30140.1 - 0.088 11.6 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Pyr_redox PF00070.22 EPE30140.1 - 0.13 12.6 0.0 4.4 7.7 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EPE30141.1 - 8.3e-53 179.5 0.0 1.1e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SPC22 PF04573.7 EPE30141.1 - 0.13 11.5 0.2 0.6 9.3 0.0 2.2 2 0 0 2 2 2 0 Signal peptidase subunit DUF829 PF05705.9 EPE30142.1 - 1.2e-35 123.3 0.0 1.4e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.11 EPE30143.1 - 2e-41 141.9 61.4 2.2e-41 141.7 40.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE30143.1 - 8.5e-19 67.1 27.2 1.2e-18 66.7 18.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE30143.1 - 2.7e-08 32.8 17.7 2.7e-08 32.8 12.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF500 PF04366.7 EPE30143.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF500) DUF4519 PF15012.1 EPE30143.1 - 0.23 11.4 0.6 0.96 9.4 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) p450 PF00067.17 EPE30144.1 - 2e-44 151.8 0.0 2.7e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 EPE30145.1 - 3e-43 147.9 60.0 3.7e-43 147.6 41.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE30145.1 - 4.9e-27 94.4 54.5 5.7e-26 90.8 37.8 1.9 1 1 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 EPE30145.1 - 0.04 13.7 0.5 0.04 13.7 0.3 3.3 3 0 0 3 3 3 0 Gram positive anchor TcdA_TcdB_pore PF12920.2 EPE30145.1 - 2.2 6.1 9.6 1.1 7.1 2.0 2.3 2 0 0 2 2 2 0 TcdA/TcdB pore forming domain MFS_1 PF07690.11 EPE30146.1 - 8.7e-44 149.6 48.5 1.3e-43 149.1 33.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TPR_12 PF13424.1 EPE30146.1 - 4e-15 55.4 3.7 2.2e-05 24.2 0.0 5.4 4 2 2 6 6 6 4 Tetratricopeptide repeat Sugar_tr PF00083.19 EPE30146.1 - 8.5e-14 50.9 15.0 8.5e-14 50.9 10.4 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter TPR_10 PF13374.1 EPE30146.1 - 3e-12 46.0 0.1 0.00066 19.5 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 EPE30146.1 - 8.3e-06 24.8 0.1 7.8e-05 21.6 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EPE30146.1 - 3.7e-05 23.8 0.0 0.00014 22.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain TPR_7 PF13176.1 EPE30146.1 - 0.12 12.2 0.3 41 4.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MARVEL PF01284.18 EPE30147.1 - 2.2e-09 37.2 7.3 4.2e-09 36.3 5.1 1.5 1 1 0 1 1 1 1 Membrane-associating domain HAD_2 PF13419.1 EPE30148.1 - 1.5e-09 38.2 0.0 0.0064 16.7 0.0 3.3 3 0 0 3 3 3 3 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE30148.1 - 3.2e-09 36.3 0.0 9.5e-09 34.8 0.0 1.8 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EPE30148.1 - 6.5e-05 23.4 0.0 0.0014 19.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GMC_oxred_C PF05199.8 EPE30149.1 - 1.1e-32 113.3 0.0 2.1e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EPE30149.1 - 2.6e-31 108.8 0.0 1.1e-22 80.5 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.19 EPE30149.1 - 6.5e-09 35.1 0.0 2.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE30149.1 - 3.7e-05 22.7 1.5 0.00059 18.7 0.2 3.0 4 0 0 4 4 4 1 FAD binding domain Pyr_redox_2 PF07992.9 EPE30149.1 - 6.9e-05 22.8 0.0 0.046 13.6 0.0 3.0 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE30149.1 - 8.4e-05 22.7 0.0 0.0044 17.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE30149.1 - 0.00079 19.3 0.4 0.0018 18.2 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPE30149.1 - 0.0031 17.2 0.1 0.02 14.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EPE30149.1 - 0.0077 15.1 0.0 0.078 11.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EPE30149.1 - 0.025 13.0 0.1 0.15 10.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 EPE30149.1 - 0.041 13.8 0.4 0.22 11.5 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain DUF1785 PF08699.5 EPE30149.1 - 0.066 12.5 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1785) Thi4 PF01946.12 EPE30149.1 - 0.087 11.9 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EPE30149.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DUF2776 PF10951.3 EPE30151.1 - 0.018 14.1 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) adh_short_C2 PF13561.1 EPE30152.1 - 3.9e-09 36.6 0.2 1.1e-08 35.1 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE30152.1 - 5.9e-08 32.8 0.0 8.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DUF4202 PF13875.1 EPE30156.1 - 2.3e-73 245.7 0.0 2.6e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Ank_2 PF12796.2 EPE30157.1 - 2.6e-30 104.5 0.1 1.4e-14 54.1 0.1 5.2 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EPE30157.1 - 3e-15 55.1 11.9 0.01 15.6 0.0 9.0 9 1 0 9 9 9 4 Ankyrin repeat Ank_4 PF13637.1 EPE30157.1 - 2.8e-14 53.1 6.3 0.61 10.6 0.0 7.6 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE30157.1 - 1e-12 46.9 6.9 1.1 9.7 0.0 9.1 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.1 EPE30157.1 - 5e-11 42.4 8.1 0.18 12.1 0.0 7.4 5 3 3 8 8 8 3 Ankyrin repeats (many copies) DHDPS PF00701.17 EPE30158.1 - 1.3e-33 115.8 0.0 1.6e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.17 EPE30159.1 - 2.3e-09 37.7 1.2 1e-08 35.7 0.8 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RE_Bsp6I PF09504.5 EPE30160.1 - 7e-05 22.3 0.1 0.00084 18.8 0.0 2.4 2 0 0 2 2 2 1 Bsp6I restriction endonuclease Chromo PF00385.19 EPE30160.1 - 0.042 13.5 4.3 0.13 11.9 2.0 2.4 1 1 1 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Ank_2 PF12796.2 EPE30161.1 - 2e-19 69.7 0.0 1.2e-05 25.4 0.0 4.6 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPE30161.1 - 9.7e-14 50.1 8.5 0.14 12.4 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 EPE30161.1 - 3.5e-12 46.4 2.0 0.0047 17.3 0.0 6.8 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE30161.1 - 2.9e-11 43.2 3.1 0.2 11.9 0.1 7.2 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.25 EPE30161.1 - 8e-08 31.7 13.0 0.34 10.8 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat Glyco_transf_8 PF01501.15 EPE30162.1 - 3.3e-07 29.8 0.4 6.8e-07 28.8 0.3 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 FtsH_ext PF06480.10 EPE30162.1 - 0.015 15.4 0.1 0.027 14.6 0.1 1.5 1 1 0 1 1 1 0 FtsH Extracellular Mannosyl_trans3 PF11051.3 EPE30162.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative Init_tRNA_PT PF04179.7 EPE30163.1 - 5.8e-113 378.1 0.0 2.6e-96 323.2 0.0 2.0 2 0 0 2 2 2 2 Initiator tRNA phosphoribosyl transferase Hexapep_2 PF14602.1 EPE30164.1 - 6.2e-14 51.2 7.2 1.9e-12 46.5 3.1 3.5 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EPE30164.1 - 5.8e-13 47.7 9.6 2.8e-11 42.3 2.7 3.4 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EPE30164.1 - 4.6e-12 45.7 0.0 7.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Nop16 PF09420.5 EPE30165.1 - 3.4e-53 180.1 3.6 3.9e-53 179.8 2.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 EHN PF06441.7 EPE30165.1 - 0.14 12.1 0.5 0.35 10.8 0.4 1.6 1 0 0 1 1 1 0 Epoxide hydrolase N terminus POPLD PF08170.7 EPE30165.1 - 0.15 11.9 1.0 0.39 10.5 0.6 1.9 1 1 0 1 1 1 0 POPLD (NUC188) domain Pkinase PF00069.20 EPE30166.1 - 8.4e-59 198.8 0.0 1.3e-58 198.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30166.1 - 2.9e-36 124.8 0.0 1.1e-35 122.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE30166.1 - 0.00019 20.4 0.0 0.00045 19.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like NCA2 PF08637.5 EPE30166.1 - 0.012 14.5 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 APH PF01636.18 EPE30166.1 - 0.049 13.3 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family TPD52 PF04201.10 EPE30166.1 - 0.91 9.2 9.4 0.76 9.4 4.6 2.0 2 0 0 2 2 2 0 Tumour protein D52 family Fungal_trans_2 PF11951.3 EPE30167.1 - 3.6e-48 164.0 0.6 6.8e-47 159.8 0.4 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE30167.1 - 9.9e-07 28.5 7.7 2.3e-06 27.3 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE30168.1 - 9.8e-09 34.4 0.0 1.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAN_2 PF08276.6 EPE30169.1 - 0.0044 16.8 1.4 0.0077 16.0 0.3 1.9 2 0 0 2 2 2 1 PAN-like domain PAN_4 PF14295.1 EPE30169.1 - 0.011 15.4 0.6 0.024 14.3 0.4 1.6 1 0 0 1 1 1 0 PAN domain Methyltransf_23 PF13489.1 EPE30170.1 - 1.4e-13 50.8 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE30170.1 - 1.9e-12 47.5 0.0 3.1e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE30170.1 - 3.7e-09 36.3 0.0 5.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE30170.1 - 1.1e-07 31.1 0.0 9.1e-07 28.2 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EPE30170.1 - 2.8e-06 27.7 0.0 5.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE30170.1 - 1.7e-05 25.0 0.0 3.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE30170.1 - 2e-05 24.6 0.1 0.0002 21.4 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE30170.1 - 3.6e-05 24.3 0.0 7.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE30170.1 - 0.013 14.9 0.1 0.03 13.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.1 EPE30170.1 - 0.017 14.7 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EPE30170.1 - 0.033 13.3 0.1 0.057 12.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RelB_N PF12910.2 EPE30170.1 - 0.1 11.9 0.2 0.26 10.6 0.1 1.7 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal Acetyltransf_1 PF00583.19 EPE30171.1 - 1.2e-10 41.3 0.0 2.6e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE30171.1 - 7.5e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE30171.1 - 4.5e-06 26.7 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE30171.1 - 0.00043 20.1 0.1 0.0024 17.7 0.0 2.1 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE30171.1 - 0.074 12.8 0.0 0.23 11.2 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein YccJ PF13993.1 EPE30171.1 - 0.1 12.7 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 YccJ-like protein Aldedh PF00171.17 EPE30173.1 - 1.5e-182 607.0 0.2 1.7e-182 606.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EPE30173.1 - 0.0017 17.6 0.1 0.07 12.3 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1487) TAXi_C PF14541.1 EPE30173.1 - 0.1 12.1 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal EMP24_GP25L PF01105.19 EPE30174.1 - 0.01 15.5 0.5 0.014 15.0 0.3 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD bZIP_2 PF07716.10 EPE30174.1 - 0.019 14.8 13.0 0.035 13.9 9.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper V_ATPase_I PF01496.14 EPE30174.1 - 0.65 7.7 0.5 0.86 7.3 0.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SGL PF08450.7 EPE30175.1 - 4.6e-69 232.5 0.4 5.4e-69 232.2 0.3 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 EPE30175.1 - 0.83 9.8 2.9 7.8 6.9 0.1 3.3 3 0 0 3 3 3 0 Two component regulator propeller DBP10CT PF08147.7 EPE30178.1 - 0.039 13.7 2.2 0.11 12.3 1.5 1.9 1 1 0 1 1 1 0 DBP10CT (NUC160) domain LOH1CR12 PF10158.4 EPE30178.1 - 0.041 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor protein Glyco_hydro_8 PF01270.12 EPE30178.1 - 0.052 12.2 0.1 0.094 11.4 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 DAO PF01266.19 EPE30179.1 - 1e-60 205.5 0.1 1.4e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE30179.1 - 9.6e-06 25.5 0.1 2.1e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EPE30179.1 - 0.00076 18.2 0.3 0.0054 15.4 0.2 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 EPE30179.1 - 0.00096 19.5 0.2 0.0086 16.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE30179.1 - 0.0079 16.0 1.4 2.7 7.8 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE30179.1 - 0.027 13.3 0.9 0.26 10.0 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 EPE30179.1 - 0.06 13.1 0.2 0.73 9.5 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mqo PF06039.10 EPE30179.1 - 0.068 11.3 0.0 6.9 4.7 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Neogenin_C PF06583.7 EPE30179.1 - 0.071 12.6 0.7 7.9 5.9 0.0 2.1 1 1 1 2 2 2 0 Neogenin C-terminus Thi4 PF01946.12 EPE30179.1 - 0.096 11.7 0.1 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Arc PF03869.9 EPE30179.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Arc-like DNA binding domain GSHPx PF00255.14 EPE30180.1 - 3.7e-41 138.8 0.0 5e-41 138.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EPE30180.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPE30180.1 - 0.0036 16.8 0.0 0.0073 15.8 0.0 1.6 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 EPE30180.1 - 0.024 14.7 0.0 0.07 13.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) Herpes_gE PF02480.11 EPE30182.1 - 0.0045 15.3 0.2 0.0084 14.4 0.0 1.5 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E Rifin_STEVOR PF02009.11 EPE30182.1 - 0.021 14.4 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Rax2 PF12768.2 EPE30182.1 - 0.067 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.5 EPE30182.1 - 0.068 12.4 1.6 0.17 11.2 1.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2207 PF09972.4 EPE30182.1 - 0.16 10.5 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FAM178 PF14816.1 EPE30182.1 - 0.25 10.0 1.1 0.32 9.6 0.7 1.0 1 0 0 1 1 1 0 Family of unknown function, FAM178 CCDC14 PF15254.1 EPE30182.1 - 4.4 5.5 7.5 5.4 5.2 5.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 DUF605 PF04652.11 EPE30182.1 - 9.4 5.5 13.3 12 5.1 9.2 1.1 1 0 0 1 1 1 0 Vta1 like SART-1 PF03343.8 EPE30183.1 - 0.00064 18.1 5.3 0.00078 17.9 3.7 1.1 1 0 0 1 1 1 1 SART-1 family Metallophos_2 PF12850.2 EPE30184.1 - 5.3e-07 29.6 0.0 8.1e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EPE30184.1 - 0.00019 20.9 5.2 0.013 14.9 0.2 2.6 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase GCV_H PF01597.14 EPE30184.1 - 0.045 13.4 0.1 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Glycine cleavage H-protein Ank_2 PF12796.2 EPE30185.1 - 1.5e-33 114.9 13.6 6.3e-10 39.2 0.0 7.1 3 3 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE30185.1 - 3.6e-16 59.1 7.4 0.0062 17.0 0.0 9.6 7 2 1 9 9 9 3 Ankyrin repeats (many copies) Ank PF00023.25 EPE30185.1 - 4e-15 54.7 22.8 0.37 10.6 0.0 10.5 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 EPE30185.1 - 8.9e-14 51.2 9.9 0.0013 18.9 0.0 8.7 8 2 2 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE30185.1 - 4.4e-09 35.7 19.1 1.2 9.5 0.0 11.2 13 0 0 13 13 13 2 Ankyrin repeat NACHT PF05729.7 EPE30185.1 - 6.8e-06 25.8 0.0 9.1e-05 22.1 0.0 2.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPE30185.1 - 3.4e-05 23.9 0.0 0.00013 21.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EPE30185.1 - 0.1 12.7 0.0 1.7 8.8 0.0 2.8 3 0 0 3 3 3 0 RNA helicase Methyltransf_28 PF02636.12 EPE30186.1 - 9.1e-81 270.9 0.0 1.2e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.20 EPE30187.1 - 8.5e-62 208.6 0.0 1.6e-61 207.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30187.1 - 1.3e-27 96.5 0.0 2.5e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE30187.1 - 0.031 13.2 0.0 0.031 13.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EPE30187.1 - 0.057 13.1 0.5 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family CR6_interact PF10147.4 EPE30187.1 - 0.97 8.7 13.0 1.7 7.8 9.0 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Rtf2 PF04641.7 EPE30187.1 - 1.3 8.1 9.7 2.2 7.4 6.7 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Period_C PF12114.3 EPE30188.1 - 0.26 10.8 11.7 0.36 10.4 8.1 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Glyco_transf_90 PF05686.7 EPE30189.1 - 7e-19 67.7 8.6 1.2e-15 57.1 4.9 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 ABA_GPCR PF12430.3 EPE30190.1 - 6.1e-52 175.6 2.9 6.1e-52 175.6 2.0 1.6 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EPE30190.1 - 2e-21 75.8 0.0 6e-21 74.2 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) Cytochrom_B561 PF03188.11 EPE30192.1 - 1.6e-06 27.9 8.0 4.2e-06 26.6 5.6 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EPE30192.1 - 0.0001 22.2 0.2 0.00025 20.9 0.2 1.6 1 0 0 1 1 1 1 DOMON domain zf-LSD1 PF06943.7 EPE30192.1 - 0.013 15.0 1.6 4.7 6.9 0.8 2.5 2 0 0 2 2 2 0 LSD1 zinc finger DUF1434 PF07254.7 EPE30192.1 - 0.016 15.0 0.2 0.046 13.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1434) DUF2306 PF10067.4 EPE30192.1 - 0.034 14.2 15.5 0.091 12.8 0.8 3.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) ABC2_membrane PF01061.19 EPE30192.1 - 0.049 12.7 12.5 0.025 13.7 5.9 2.0 2 0 0 2 2 2 0 ABC-2 type transporter DUF2427 PF10348.4 EPE30192.1 - 0.12 11.9 9.8 0.031 13.8 3.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Paf67 PF10255.4 EPE30193.1 - 5.2e-154 512.9 0.0 6e-154 512.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EPE30193.1 - 0.02 14.7 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Usp PF00582.21 EPE30194.1 - 2.2e-12 47.3 0.1 6.7e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Universal stress protein family Pkinase PF00069.20 EPE30195.1 - 9.7e-58 195.3 0.0 2.6e-57 193.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30195.1 - 4.1e-36 124.3 0.0 2.2e-35 121.9 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE30195.1 - 1.4e-08 34.0 0.0 2.1e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DEAD PF00270.24 EPE30196.1 - 1.9e-40 138.1 0.0 4.2e-40 137.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE30196.1 - 2.3e-26 91.4 0.1 7.9e-26 89.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPE30196.1 - 1e-05 24.4 0.0 1.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EPE30196.1 - 0.00033 20.5 0.0 0.00078 19.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_23 PF13489.1 EPE30197.1 - 2.1e-10 40.5 0.0 3.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE30197.1 - 1.2e-06 29.0 0.0 2.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE30197.1 - 8.7e-05 22.1 0.0 0.002 17.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE30197.1 - 0.00012 22.4 0.0 0.00088 19.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE30197.1 - 0.00013 22.3 0.0 0.00053 20.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EPE30197.1 - 0.00038 19.2 0.0 0.0077 14.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 EPE30197.1 - 0.0091 16.0 0.0 0.024 14.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE30197.1 - 0.011 15.1 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 EPE30197.1 - 0.022 15.1 0.0 0.059 13.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EPE30197.1 - 0.033 13.2 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase ABM PF03992.11 EPE30198.1 - 1.6e-13 50.4 0.0 1.9e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SAD_SRA PF02182.12 EPE30199.1 - 2.4e-06 26.9 0.1 6.1e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 SAD/SRA domain TruD PF01142.13 EPE30200.1 - 2.1e-53 181.3 1.0 1.2e-49 168.9 0.0 4.1 3 2 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) CDO_I PF05995.7 EPE30201.1 - 2.5e-40 137.4 0.0 3e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EPE30201.1 - 0.0033 16.8 0.2 0.01 15.1 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) Auxin_BP PF02041.11 EPE30201.1 - 0.05 13.0 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein Rotamase PF00639.16 EPE30202.1 - 2.6e-14 53.6 0.1 4.1e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EPE30202.1 - 7.9e-14 51.9 0.2 1.1e-13 51.4 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EPE30202.1 - 0.0017 19.0 0.1 0.0019 18.8 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Transketolase_N PF00456.16 EPE30202.1 - 0.064 12.0 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Ribosomal_L7Ae PF01248.21 EPE30203.1 - 4.5e-28 96.5 1.1 6.3e-28 96.1 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_S8 PF00410.14 EPE30204.1 - 2.5e-24 85.5 0.1 3.6e-24 85.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Peptidase_M41 PF01434.13 EPE30208.1 - 1.1e-75 253.7 0.1 1.8e-75 253.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EPE30208.1 - 6.9e-42 142.7 0.0 1.6e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EPE30208.1 - 7.9e-08 32.4 0.0 2.2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EPE30208.1 - 0.00022 20.9 0.0 0.00083 19.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPE30208.1 - 0.0033 17.1 0.4 0.011 15.4 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EPE30208.1 - 0.0057 16.7 1.6 0.18 11.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPE30208.1 - 0.006 16.0 1.2 0.034 13.5 0.1 2.6 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EPE30208.1 - 0.0073 16.3 0.1 0.11 12.4 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EPE30208.1 - 0.014 14.4 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EPE30208.1 - 0.015 14.0 0.1 0.029 13.0 0.1 1.4 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 EPE30208.1 - 0.025 13.9 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 EPE30208.1 - 0.027 14.4 0.0 0.079 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EPE30208.1 - 0.045 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPE30208.1 - 0.083 13.7 0.0 0.22 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EPE30208.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Fungal_trans PF04082.13 EPE30209.1 - 3.2e-30 104.8 0.0 6.4e-30 103.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE30209.1 - 2.5e-10 40.0 11.7 5e-10 39.1 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syntaxin-6_N PF09177.6 EPE30209.1 - 0.15 12.4 0.2 15 6.0 0.0 3.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal SKG6 PF08693.5 EPE30210.1 - 0.12 11.7 0.3 0.47 9.8 0.2 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_C62 PF12380.3 EPE30210.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase Abhydrolase_6 PF12697.2 EPE30211.1 - 8.8e-06 25.7 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE30211.1 - 1.7e-05 24.5 0.0 5.1e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EPE30211.1 - 0.0018 17.5 0.0 0.005 16.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EPE30211.1 - 0.0027 17.3 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 EPE30211.1 - 0.0028 17.2 0.0 0.0075 15.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EPE30211.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) HCO3_cotransp PF00955.16 EPE30212.1 - 6.9e-61 206.4 14.3 1.8e-38 132.5 3.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family FAD_binding_4 PF01565.18 EPE30213.1 - 2.1e-15 56.4 0.0 3.7e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain A_deaminase PF00962.17 EPE30214.1 - 2.2e-41 141.8 0.0 4.7e-41 140.8 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.6 EPE30214.1 - 0.047 12.8 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family Radical_SAM PF04055.16 EPE30214.1 - 0.075 13.1 0.3 1.1 9.4 0.1 2.5 1 1 1 2 2 2 0 Radical SAM superfamily MFS_1 PF07690.11 EPE30215.1 - 1.2e-30 106.4 23.3 1.7e-30 105.9 16.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FAM91_C PF14648.1 EPE30215.1 - 0.21 10.4 0.3 0.33 9.7 0.2 1.2 1 0 0 1 1 1 0 FAM91 C-terminus Taeniidae_ag PF05596.6 EPE30217.1 - 0.076 12.8 0.1 0.55 10.0 0.0 2.2 2 0 0 2 2 2 0 Taeniidae antigen Fez1 PF06818.10 EPE30218.1 - 0.049 13.6 2.0 0.064 13.2 1.4 1.1 1 0 0 1 1 1 0 Fez1 Paf1 PF03985.8 EPE30219.1 - 4.1e-49 167.5 0.8 8.6e-49 166.4 0.6 1.5 1 1 0 1 1 1 1 Paf1 VPS9 PF02204.13 EPE30220.1 - 6.7e-25 87.1 0.0 1.2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.20 EPE30221.1 - 9.8e-05 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) ECH PF00378.15 EPE30222.1 - 4.6e-67 225.7 0.0 5.8e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EPE30222.1 - 0.12 12.5 0.1 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Rer1 PF03248.8 EPE30223.1 - 7.9e-82 273.0 3.4 9.1e-82 272.9 2.4 1.0 1 0 0 1 1 1 1 Rer1 family Glyco_hydro_30 PF02055.11 EPE30224.1 - 7.2e-23 80.5 0.2 3.1e-15 55.3 0.1 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EPE30224.1 - 5.1e-21 75.0 2.0 3.1e-18 65.8 0.0 2.5 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 DUF3328 PF11807.3 EPE30225.1 - 2.6e-53 180.8 0.3 3.4e-53 180.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TRAP_beta PF05753.9 EPE30225.1 - 0.026 13.6 0.0 0.076 12.1 0.0 1.7 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) TPR_8 PF13181.1 EPE30227.1 - 1.9e-08 33.5 0.0 0.0059 16.2 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPE30227.1 - 6.2e-08 32.6 5.3 0.017 15.7 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPE30227.1 - 2.8e-07 31.0 4.7 0.35 11.6 0.4 6.2 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPE30227.1 - 5.5e-07 29.8 0.2 0.0037 17.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPE30227.1 - 4.2e-06 26.2 5.5 0.067 13.1 0.1 7.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPE30227.1 - 9.4e-06 25.1 1.3 0.82 9.3 0.0 5.7 8 0 0 8 8 8 2 TPR repeat TPR_17 PF13431.1 EPE30227.1 - 4.9e-05 23.2 0.1 0.003 17.6 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPE30227.1 - 7.3e-05 22.6 3.0 23 5.0 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPE30227.1 - 0.0001 21.7 0.1 3.7 7.2 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPE30227.1 - 0.00011 22.3 0.6 0.14 12.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 EPE30227.1 - 0.00096 19.3 2.0 0.97 10.0 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE30227.1 - 0.0031 17.2 0.5 3 7.8 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat RIX1 PF08167.7 EPE30228.1 - 7.4e-49 165.6 0.8 1.4e-48 164.7 0.6 1.4 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis peroxidase PF00141.18 EPE30229.1 - 4.3e-28 98.3 0.1 6.4e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EPE30229.1 - 0.038 13.8 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) Glyco_transf_54 PF04666.8 EPE30230.1 - 5.9e-10 38.3 0.1 1.1e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region F5_F8_type_C PF00754.20 EPE30231.1 - 2.4e-05 24.1 0.2 5.5e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 F5/8 type C domain Glyco_hydro_43 PF04616.9 EPE30232.1 - 1.4e-63 214.6 14.1 1.5e-55 188.3 1.3 3.0 2 1 1 3 3 3 3 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EPE30232.1 - 6.7e-09 35.5 0.6 0.00022 20.6 0.0 3.3 3 1 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Pkinase PF00069.20 EPE30234.1 - 5.1e-26 91.3 0.1 2e-12 46.8 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30234.1 - 1.5e-09 37.3 0.0 0.00014 21.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 EPE30234.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family HeLo PF14479.1 EPE30235.1 - 3.2e-11 43.3 0.4 4e-11 43.0 0.3 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation RF-1 PF00472.15 EPE30235.1 - 0.12 12.2 0.2 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 RF-1 domain MAPEG PF01124.13 EPE30236.1 - 7.1e-12 45.0 0.3 9.9e-12 44.5 0.2 1.2 1 0 0 1 1 1 1 MAPEG family DUF1996 PF09362.5 EPE30237.1 - 3.9e-91 304.8 0.6 4.9e-91 304.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NMT1 PF09084.6 EPE30238.1 - 4.1e-11 42.9 0.1 6.5e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EPE30238.1 - 0.00089 18.5 0.0 0.0018 17.5 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 FAD_binding_5 PF00941.16 EPE30238.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase Ligase_CoA PF00549.14 EPE30238.1 - 0.086 12.4 0.5 0.34 10.5 0.0 2.1 2 1 1 3 3 3 0 CoA-ligase MARVEL PF01284.18 EPE30239.1 - 2.1e-06 27.5 14.8 3.2e-06 27.0 10.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.1 EPE30239.1 - 7.7 5.7 11.0 0.4 9.9 4.0 1.4 2 0 0 2 2 2 0 ABC-2 family transporter protein PTR2 PF00854.16 EPE30241.1 - 1e-24 87.0 7.1 1e-24 87.0 4.9 2.5 2 1 0 2 2 2 1 POT family DUF2649 PF10854.3 EPE30241.1 - 0.016 15.3 1.1 0.06 13.4 0.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) Prefoldin_3 PF13758.1 EPE30242.1 - 2.7e-32 110.4 0.7 2.7e-32 110.4 0.5 2.0 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 EPE30242.1 - 2.1e-23 83.0 6.8 2.4e-20 73.2 0.0 4.5 5 0 0 5 5 5 2 Domain of unknown function (DUF3835) UAA PF08449.6 EPE30243.1 - 9e-72 241.5 7.1 3.1e-71 239.7 4.9 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPE30243.1 - 3.7e-08 33.4 21.6 4.5e-07 29.9 2.9 3.4 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EPE30243.1 - 1.8e-07 31.3 20.3 2.8e-06 27.4 3.6 3.1 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EPE30243.1 - 3.3e-07 29.6 2.4 0.0016 17.5 0.1 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 EPE30243.1 - 0.64 9.6 17.1 0.068 12.8 5.6 2.5 2 1 0 2 2 2 0 Triose-phosphate Transporter family Cofilin_ADF PF00241.15 EPE30244.1 - 2.4e-17 62.9 0.0 2.7e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein KH_1 PF00013.24 EPE30245.1 - 9.5e-39 130.8 13.1 4.6e-15 55.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EPE30245.1 - 1.3e-29 101.2 13.0 2.9e-11 42.7 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EPE30245.1 - 1.6e-10 40.4 6.0 0.01 15.3 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EPE30245.1 - 3.3e-08 33.0 4.7 0.053 13.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EPE30245.1 - 0.00019 21.1 4.2 0.72 9.6 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EPE30245.1 - 0.01 15.2 0.4 0.46 9.9 0.0 2.8 3 0 0 3 3 3 0 dUTPase RabGAP-TBC PF00566.13 EPE30246.1 - 9.1e-33 113.5 3.0 2.4e-32 112.1 2.1 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DAHP_synth_2 PF01474.11 EPE30249.1 - 6.9e-192 637.6 0.0 7.9e-192 637.4 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family UBA_4 PF14555.1 EPE30250.1 - 0.024 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Antitoxin-MazE PF04014.13 EPE30251.1 - 0.062 13.0 0.5 0.15 11.8 0.4 1.6 1 0 0 1 1 1 0 Antidote-toxin recognition MazE Aldolase_II PF00596.16 EPE30252.1 - 2.6e-41 141.2 0.0 3e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.13 EPE30253.1 - 2.8e-155 516.4 16.6 3.6e-155 516.1 11.5 1.1 1 0 0 1 1 1 1 Calreticulin family DUF4407 PF14362.1 EPE30254.1 - 0.016 14.1 0.4 0.017 14.0 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.6 EPE30254.1 - 0.017 14.8 0.2 0.021 14.5 0.2 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ATG16 PF08614.6 EPE30254.1 - 0.03 14.1 0.2 0.035 13.9 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AhpC-TSA PF00578.16 EPE30255.1 - 4.7e-31 107.0 0.0 6.4e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPE30255.1 - 3.4e-12 46.1 0.0 4.2e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EPE30255.1 - 4.6e-11 42.1 0.0 8.3e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.11 EPE30256.1 - 6.5e-38 130.3 29.0 6.5e-38 130.3 20.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE30256.1 - 2.1e-09 36.4 6.3 2.1e-09 36.4 4.4 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter Myco_arth_vir_N PF09610.5 EPE30256.1 - 0.011 15.6 1.0 0.047 13.6 0.0 2.6 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Transgly_assoc PF04226.8 EPE30256.1 - 0.011 15.7 4.9 0.013 15.6 1.8 2.4 2 0 0 2 2 2 0 Transglycosylase associated protein P12 PF12669.2 EPE30257.1 - 0.33 11.1 3.7 13 6.0 0.5 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family Exo_endo_phos PF03372.18 EPE30258.1 - 1.7e-17 64.1 0.3 2e-17 63.9 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HpcH_HpaI PF03328.9 EPE30259.1 - 1.9e-42 144.6 0.0 5.1e-42 143.2 0.0 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EPE30259.1 - 4.7e-15 55.2 0.0 4.2e-07 29.1 0.0 2.0 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.16 EPE30259.1 - 0.01 14.5 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain DUF3860 PF12976.2 EPE30259.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) BolA PF01722.13 EPE30262.1 - 2.8e-26 91.2 2.2 3.5e-26 90.9 1.6 1.1 1 0 0 1 1 1 1 BolA-like protein RPA_C PF08784.6 EPE30262.1 - 0.0086 16.4 0.1 0.011 16.1 0.1 1.2 1 0 0 1 1 1 1 Replication protein A C terminal Beta-lactamase PF00144.19 EPE30262.1 - 0.047 12.7 0.0 0.052 12.5 0.0 1.0 1 0 0 1 1 1 0 Beta-lactamase FAD_binding_3 PF01494.14 EPE30263.1 - 1.3e-13 50.7 7.2 1.9e-12 46.9 0.2 3.1 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 EPE30263.1 - 1.9e-07 30.3 0.2 0.00036 19.5 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPE30263.1 - 0.0002 21.1 0.0 0.00052 19.8 0.0 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EPE30263.1 - 0.00044 20.2 2.8 0.00048 20.0 0.7 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EPE30263.1 - 0.00048 19.0 0.0 0.0078 15.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.19 EPE30263.1 - 0.0034 16.5 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EPE30263.1 - 0.024 15.0 2.6 0.15 12.4 0.5 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE30263.1 - 0.044 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE30263.1 - 0.084 11.9 0.4 0.14 11.2 0.3 1.3 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.11 EPE30264.1 - 3e-23 82.1 22.7 3e-23 82.1 15.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF202 PF02656.10 EPE30265.1 - 4.9 7.4 6.4 22 5.3 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Pkinase PF00069.20 EPE30266.1 - 0.023 13.8 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain TPR_11 PF13414.1 EPE30269.1 - 2.8e-11 42.9 5.2 1.4e-09 37.4 0.1 2.7 2 1 1 3 3 2 2 TPR repeat TPR_1 PF00515.23 EPE30269.1 - 8.6e-09 34.6 1.3 0.068 12.8 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat SET PF00856.23 EPE30269.1 - 2.6e-08 34.3 0.1 4.5e-07 30.3 0.1 2.4 2 0 0 2 2 2 1 SET domain TPR_2 PF07719.12 EPE30269.1 - 7.1e-08 31.7 1.6 0.0022 17.7 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPE30269.1 - 3.2e-07 30.3 1.6 1.8e-05 24.9 0.5 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE30269.1 - 5.7e-05 23.3 1.2 0.64 10.8 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPE30269.1 - 0.0008 19.0 5.7 0.016 14.9 1.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EPE30269.1 - 0.0016 18.5 2.2 0.0078 16.3 1.6 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EPE30269.1 - 0.0073 16.9 2.8 0.23 12.2 2.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPE30269.1 - 0.01 15.6 0.5 0.21 11.4 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPE30269.1 - 0.036 14.0 8.0 0.38 10.7 2.7 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPE30269.1 - 0.048 13.5 0.4 5.1 7.0 0.1 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 EPE30269.1 - 0.053 13.4 1.2 0.45 10.4 1.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPE30269.1 - 0.08 13.4 0.3 0.35 11.4 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPE30269.1 - 0.1 12.9 3.0 1.6 9.1 0.7 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPE30269.1 - 0.17 12.1 0.8 3.5 8.0 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPE30269.1 - 1.7 8.6 4.8 1e+02 3.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol3_tau_4 PF12168.3 EPE30270.1 - 3.5 8.1 7.2 0.66 10.4 1.7 2.1 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding adh_short_C2 PF13561.1 EPE30271.1 - 2.2e-28 99.6 0.0 3e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE30271.1 - 2.9e-27 95.6 2.2 3.8e-27 95.2 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE30271.1 - 2.8e-16 59.7 1.0 4.1e-16 59.1 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE30271.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE30271.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Exo_endo_phos PF03372.18 EPE30272.1 - 1.2e-08 35.2 0.0 1.5e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2007 PF09413.5 EPE30273.1 - 0.036 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) Glyco_hydro_61 PF03443.9 EPE30275.1 - 1.4e-35 123.1 0.0 2.9e-35 122.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 DltD_C PF04914.7 EPE30276.1 - 0.086 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 DltD C-terminal region Pkinase PF00069.20 EPE30277.1 - 5.4e-18 65.0 0.0 6.8e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30277.1 - 1.4e-05 24.2 0.0 2.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UQ_con PF00179.21 EPE30278.1 - 2.1e-26 92.0 0.0 4.2e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.1 EPE30278.1 - 2.9e-19 69.8 0.0 5.5e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EPE30278.1 - 9.7e-13 48.2 0.0 1.7e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_hydro_43 PF04616.9 EPE30279.1 - 1e-14 54.2 5.9 1.3e-08 34.2 0.7 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 zf-RING_4 PF14570.1 EPE30280.1 - 7.1e-05 22.3 6.6 0.0011 18.5 2.9 2.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EPE30280.1 - 0.00039 20.1 8.8 0.00097 18.9 3.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE30280.1 - 0.00052 19.9 9.4 0.00062 19.7 4.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE30280.1 - 0.00069 19.2 6.1 0.0016 18.0 2.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE30280.1 - 0.0021 17.6 6.9 0.019 14.6 2.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPE30280.1 - 0.047 13.5 7.5 0.25 11.2 3.1 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Cation_ATPase_C PF00689.16 EPE30281.1 - 0.13 11.7 9.4 0.6 9.5 2.3 2.4 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Tmemb_18A PF09771.4 EPE30281.1 - 0.38 10.7 5.0 0.4 10.6 1.5 2.4 2 0 0 2 2 2 0 Transmembrane protein 188 Fungal_trans_2 PF11951.3 EPE30282.1 - 1.1e-05 24.1 0.7 4e-05 22.3 0.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ank PF00023.25 EPE30285.1 - 4.7e-17 60.8 2.3 5.2e-07 29.1 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EPE30285.1 - 5.9e-17 61.8 0.6 0.0028 17.9 0.0 3.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPE30285.1 - 2.3e-15 56.2 3.6 2e-06 27.8 0.2 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE30285.1 - 3.9e-12 46.3 2.5 2.5e-06 27.8 0.0 5.0 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE30285.1 - 6.4e-12 44.4 1.4 0.00042 20.2 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat PQ-loop PF04193.9 EPE30287.1 - 1.5e-23 82.1 5.6 4.4e-14 51.7 1.9 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF1290 PF06947.7 EPE30287.1 - 5.3 7.0 8.7 0.53 10.2 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1290) Chromo PF00385.19 EPE30288.1 - 0.00066 19.2 2.5 0.0012 18.4 1.8 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF572 PF04502.8 EPE30288.1 - 0.27 10.4 7.9 0.29 10.3 5.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GAPT PF11770.3 EPE30288.1 - 0.39 10.3 1.7 0.5 10.0 0.7 1.4 1 1 0 1 1 1 0 GRB2-binding adapter (GAPT) Bac_chlorC PF02043.12 EPE30288.1 - 7.7 6.3 6.3 8.2 6.2 0.3 2.4 1 1 1 2 2 2 0 Bacteriochlorophyll C binding protein zf-RING_2 PF13639.1 EPE30290.1 - 2.5e-07 30.3 9.7 4.3e-07 29.6 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE30290.1 - 1.8e-06 27.8 7.9 3.3e-06 27.0 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE30290.1 - 2.7e-06 26.9 8.3 4.8e-06 26.1 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE30290.1 - 6.2e-06 25.8 8.4 1.1e-05 25.1 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE30290.1 - 1.6e-05 24.4 6.7 3.2e-05 23.4 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPE30290.1 - 0.00029 20.4 4.5 0.00062 19.4 3.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EPE30290.1 - 0.00038 19.9 6.9 0.00076 19.0 4.8 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EPE30290.1 - 0.0063 16.3 6.1 0.012 15.4 4.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EPE30290.1 - 0.0064 16.5 3.3 0.014 15.4 2.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FYVE PF01363.16 EPE30290.1 - 0.084 12.7 3.2 0.16 11.8 2.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-Apc11 PF12861.2 EPE30290.1 - 0.085 12.7 1.9 0.18 11.6 1.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EPE30290.1 - 0.14 11.7 6.6 0.32 10.5 4.6 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-CHY PF05495.7 EPE30290.1 - 0.26 11.4 7.1 0.62 10.2 4.9 1.7 1 0 0 1 1 1 0 CHY zinc finger NMD3 PF04981.8 EPE30290.1 - 1.1 8.2 4.4 2.2 7.3 3.1 1.5 1 0 0 1 1 1 0 NMD3 family Prok-RING_4 PF14447.1 EPE30290.1 - 6.3 6.4 10.9 4.5e+02 0.4 7.6 3.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Lipase_GDSL PF00657.17 EPE30291.1 - 1.6e-18 67.3 0.0 1.9e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EPE30291.1 - 2.9e-11 43.8 1.4 4.9e-11 43.0 1.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Aminotran_1_2 PF00155.16 EPE30292.1 - 8.3e-45 153.2 0.0 1.1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPE30292.1 - 0.0051 16.0 0.0 0.0093 15.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Glyco_hydro_7 PF00840.15 EPE30293.1 - 1.9e-143 477.9 6.6 2.3e-143 477.6 4.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Kelch_1 PF01344.20 EPE30294.1 - 6.9e-32 108.7 9.4 9.3e-09 34.6 0.2 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EPE30294.1 - 1.3e-23 82.0 22.0 2e-08 34.0 0.3 6.4 3 1 4 7 7 7 4 Kelch motif Kelch_4 PF13418.1 EPE30294.1 - 3.8e-21 74.5 13.0 0.00029 20.5 0.1 7.1 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EPE30294.1 - 2.5e-16 59.3 10.3 0.0008 19.4 0.5 6.6 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EPE30294.1 - 1.2e-11 43.9 16.3 0.0081 15.8 0.3 6.9 6 2 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EPE30294.1 - 1.5e-05 24.8 15.9 0.44 10.5 0.0 6.2 6 1 0 6 6 6 3 Kelch motif DUF1668 PF07893.8 EPE30294.1 - 0.03 13.4 0.1 0.37 9.8 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1668) CBM_20 PF00686.14 EPE30294.1 - 0.078 12.5 0.1 0.49 10.0 0.0 2.4 2 0 0 2 2 2 0 Starch binding domain PQQ_3 PF13570.1 EPE30294.1 - 0.09 13.0 16.4 12 6.3 0.1 5.6 6 0 0 6 6 6 0 PQQ-like domain NACHT PF05729.7 EPE30296.1 - 6.2e-08 32.4 0.0 1.7e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EPE30296.1 - 0.00011 22.3 0.0 0.00068 19.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EPE30296.1 - 0.0021 16.9 0.1 0.0079 15.0 0.1 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA_10 PF12846.2 EPE30296.1 - 0.0035 16.8 0.3 0.051 12.9 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain AAA_16 PF13191.1 EPE30296.1 - 0.0037 17.2 0.1 0.032 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 EPE30296.1 - 0.017 15.4 0.0 0.13 12.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 EPE30296.1 - 0.029 14.5 0.3 0.089 12.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.1 EPE30296.1 - 0.038 13.5 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EPE30296.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein UQ_con PF00179.21 EPE30297.1 - 5.7e-16 58.2 0.1 9.9e-16 57.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPE30297.1 - 0.00068 19.5 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 RWD domain F-box-like PF12937.2 EPE30297.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 F-box-like FAD_binding_3 PF01494.14 EPE30298.1 - 3.6e-91 305.8 0.0 4.4e-91 305.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE30298.1 - 1.8e-10 40.2 1.9 0.0005 19.0 0.0 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPE30298.1 - 4.8e-07 29.8 0.2 7e-06 26.0 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE30298.1 - 0.00046 20.2 0.1 0.0022 18.0 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE30298.1 - 0.0022 16.9 0.1 0.11 11.3 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EPE30298.1 - 0.0032 17.8 0.1 1.4 9.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE30298.1 - 0.0048 16.8 0.0 0.019 15.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EPE30298.1 - 0.0083 15.2 0.1 0.059 12.4 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EPE30298.1 - 0.037 12.6 0.8 0.83 8.2 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase zf-RING_2 PF13639.1 EPE30299.1 - 2.4e-06 27.2 5.9 2.4e-06 27.2 4.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EPE30299.1 - 0.00028 20.5 5.1 0.00028 20.5 3.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE30299.1 - 0.0019 17.8 6.3 0.0019 17.8 4.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 EPE30299.1 - 0.0045 16.7 1.7 0.0045 16.7 1.2 2.1 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 EPE30299.1 - 0.8 9.3 10.3 0.2 11.2 3.4 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Mem_trans PF03547.13 EPE30300.1 - 2.4e-27 95.2 0.8 3.4e-27 94.7 0.6 1.2 1 0 0 1 1 1 1 Membrane transport protein TMEM169 PF15052.1 EPE30300.1 - 1.7 8.5 7.0 0.16 11.8 0.5 2.5 3 0 0 3 3 3 0 TMEM169 protein family adh_short PF00106.20 EPE30301.1 - 1.5e-11 44.4 0.1 9e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE30301.1 - 0.0001 22.0 0.1 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 KR domain GSDH PF07995.6 EPE30303.1 - 8.3e-116 386.6 0.1 9.6e-116 386.4 0.0 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 EPE30303.1 - 4.6e-05 23.1 0.0 0.14 12.1 0.0 3.8 3 0 0 3 3 3 1 NHL repeat Reg_prop PF07494.6 EPE30303.1 - 0.028 14.4 0.7 67 4.0 0.0 4.0 4 0 0 4 4 4 0 Two component regulator propeller Rick_17kDa_Anti PF05433.10 EPE30304.1 - 0.0026 17.3 17.2 0.0042 16.7 11.9 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EPE30304.1 - 0.0029 17.2 4.2 0.0029 17.2 2.9 1.9 2 0 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 EPE30304.1 - 0.0041 16.7 11.1 0.0079 15.8 7.7 1.5 1 0 0 1 1 1 1 Glycine zipper TFIIA PF03153.8 EPE30304.1 - 0.015 15.2 8.4 0.016 15.0 5.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Bacteriocin_IIc PF10439.4 EPE30304.1 - 0.38 10.9 9.7 0.54 10.4 6.7 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 EPE30304.1 - 8 6.0 16.9 19 4.8 11.2 1.9 1 1 1 2 2 2 0 YMGG-like Gly-zipper HET PF06985.6 EPE30305.1 - 2.6e-36 124.8 0.7 5.4e-36 123.8 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ThylakoidFormat PF11264.3 EPE30305.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Thylakoid formation protein ketoacyl-synt PF00109.21 EPE30306.1 - 3.5e-69 233.1 0.0 7.3e-69 232.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPE30306.1 - 2.8e-66 224.0 0.5 4.3e-66 223.4 0.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EPE30306.1 - 1.4e-63 213.8 0.1 4.3e-63 212.2 0.0 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EPE30306.1 - 9.5e-52 175.2 0.1 9.5e-52 175.2 0.1 2.9 4 0 0 4 4 4 1 short chain dehydrogenase PS-DH PF14765.1 EPE30306.1 - 4.9e-48 163.7 0.0 1e-47 162.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EPE30306.1 - 3.6e-42 142.9 0.0 1.9e-41 140.6 0.0 2.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EPE30306.1 - 1.1e-15 57.3 0.9 5.1e-15 55.1 0.1 2.7 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE30306.1 - 2.5e-15 57.4 0.0 1.3e-14 55.1 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EPE30306.1 - 4.1e-07 30.1 0.1 9.3e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EPE30306.1 - 1e-06 28.4 1.5 1.7e-06 27.7 0.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.10 EPE30306.1 - 0.0079 15.1 0.0 0.017 13.9 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FSH1 PF03959.8 EPE30307.1 - 5.7e-26 91.2 0.0 9.2e-26 90.5 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF1993 PF09351.5 EPE30308.1 - 1.4e-47 161.6 0.2 1.6e-47 161.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) TBCA PF02970.11 EPE30308.1 - 0.089 12.8 0.3 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 Tubulin binding cofactor A POX PF07526.6 EPE30308.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 1 0 1 1 1 0 Associated with HOX AAA_16 PF13191.1 EPE30309.1 - 5.2e-07 29.8 0.1 2.5e-06 27.5 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain Ank_2 PF12796.2 EPE30309.1 - 0.00023 21.4 0.0 0.0019 18.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) NACHT PF05729.7 EPE30309.1 - 0.00031 20.4 0.0 0.00081 19.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank PF00023.25 EPE30309.1 - 0.00076 19.1 0.3 1.2 9.0 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat AAA_22 PF13401.1 EPE30309.1 - 0.004 17.2 1.2 0.08 13.0 0.0 3.6 4 1 0 4 4 4 1 AAA domain Ank_5 PF13857.1 EPE30309.1 - 0.0096 16.1 0.1 1.3 9.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE30309.1 - 0.026 15.0 0.1 8.5 7.0 0.0 2.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE30309.1 - 0.063 13.5 0.1 5.3 7.5 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat AAA_14 PF13173.1 EPE30309.1 - 0.098 12.5 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EPE30309.1 - 0.099 12.8 0.1 0.85 9.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3918 PF13056.1 EPE30310.1 - 0.067 12.5 0.5 0.067 12.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) DUF2484 PF10658.4 EPE30312.1 - 0.54 10.4 6.0 0.17 11.9 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) VWA_3 PF13768.1 EPE30314.1 - 1.4e-29 102.7 0.0 4e-29 101.3 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 EPE30314.1 - 5.5e-19 68.0 0.0 1.7e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.1 EPE30314.1 - 1.3e-09 37.3 0.0 2.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EPE30314.1 - 1.5e-09 38.1 0.1 4.2e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EPE30314.1 - 7.6e-08 32.2 0.0 1.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EPE30314.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Ish1 PF10281.4 EPE30315.1 - 0.068 13.2 1.3 0.23 11.5 0.1 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein SID PF11778.3 EPE30315.1 - 0.092 12.6 2.6 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 Septation initiation Bac_rhamnosid PF05592.6 EPE30316.1 - 1.4e-42 145.5 0.0 5.3e-38 130.5 0.0 2.4 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EPE30316.1 - 1.6e-06 27.0 0.0 2.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 EPE30316.1 - 0.00017 20.4 0.0 0.00036 19.3 0.0 1.5 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Epimerase PF01370.16 EPE30317.1 - 1.5e-14 53.9 0.0 2.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE30317.1 - 2e-11 43.1 0.0 4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPE30317.1 - 2.1e-10 40.9 0.5 6e-10 39.4 0.4 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPE30317.1 - 6.5e-06 25.2 0.1 9.4e-06 24.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EPE30317.1 - 0.00034 19.9 0.5 0.00067 18.9 0.3 1.6 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EPE30317.1 - 0.00043 20.2 0.1 0.00089 19.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EPE30317.1 - 0.00064 18.7 0.5 0.011 14.6 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein PQ-loop PF04193.9 EPE30318.1 - 5.4e-20 70.6 2.8 8.6e-12 44.4 0.0 3.0 3 0 0 3 3 3 2 PQ loop repeat Cmc1 PF08583.5 EPE30318.1 - 0.017 14.8 2.0 0.034 13.9 1.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like adh_short PF00106.20 EPE30319.1 - 1.1e-20 74.2 0.0 1.4e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE30319.1 - 4.7e-10 39.4 0.2 1.9e-09 37.4 0.1 1.8 1 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EPE30319.1 - 1.7e-07 31.2 0.0 2.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPE30319.1 - 0.0096 15.3 0.4 0.27 10.6 0.3 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CW_binding_2 PF04122.7 EPE30319.1 - 0.012 15.8 0.4 0.023 14.8 0.3 1.4 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Polysacc_synt_2 PF02719.10 EPE30319.1 - 0.02 13.8 0.1 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EPE30319.1 - 0.02 14.9 0.5 0.032 14.3 0.3 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EPE30319.1 - 0.12 11.3 0.3 0.16 10.9 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EPE30319.1 - 0.21 11.3 3.1 0.62 9.8 1.7 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aldose_epim PF01263.15 EPE30321.1 - 1.1e-38 133.0 0.0 1.4e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Rif1_N PF12231.3 EPE30324.1 - 2e-108 362.6 1.7 3.1e-108 362.0 1.2 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Arf PF00025.16 EPE30324.1 - 0.27 10.4 0.0 0.51 9.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Ric8 PF10165.4 EPE30325.1 - 2.6e-115 385.7 0.1 3.1e-115 385.5 0.1 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn FlxA PF14282.1 EPE30325.1 - 0.15 11.9 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 FlxA-like protein p450 PF00067.17 EPE30327.1 - 1e-41 142.9 0.0 1.8e-41 142.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Tannase PF07519.6 EPE30331.1 - 2.3e-77 260.7 0.0 3.2e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EPE30331.1 - 0.00014 21.7 0.1 0.00052 19.9 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE30331.1 - 0.0027 17.4 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE30331.1 - 0.029 13.5 0.0 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Sugar_tr PF00083.19 EPE30333.1 - 8.9e-37 126.7 0.0 1.1e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE30333.1 - 3e-12 45.9 0.1 3.4e-12 45.7 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.10 EPE30333.1 - 0.0086 14.8 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 PUCC protein Glyco_hydro_3 PF00933.16 EPE30335.1 - 1.8e-27 96.1 0.0 1.9e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fungal_trans PF04082.13 EPE30336.1 - 5.9e-07 28.6 0.3 1.5e-06 27.2 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE30336.1 - 5.2e-05 23.0 8.1 5.2e-05 23.0 5.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EPE30336.1 - 3.3 7.9 8.9 7.3 6.8 6.2 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region adh_short PF00106.20 EPE30337.1 - 7.4e-17 61.7 0.9 1e-16 61.2 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE30337.1 - 8.8e-07 28.7 0.2 1.6e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPE30337.1 - 0.0071 16.1 0.1 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EPE30337.1 - 0.062 12.1 0.0 0.087 11.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YuzL PF14115.1 EPE30338.1 - 0.022 15.0 2.0 0.022 15.0 1.4 1.6 2 0 0 2 2 2 0 YuzL-like protein HNH_2 PF13391.1 EPE30339.1 - 1.8e-10 40.4 0.1 7e-10 38.5 0.0 2.1 1 1 1 2 2 2 1 HNH endonuclease p450 PF00067.17 EPE30340.1 - 0.028 12.9 0.0 0.034 12.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 p450 PF00067.17 EPE30341.1 - 9.2e-75 251.9 0.0 1.1e-74 251.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ELO PF01151.13 EPE30342.1 - 1.1e-43 149.3 10.6 9.8e-24 84.0 1.0 2.1 1 1 1 2 2 2 2 GNS1/SUR4 family Nup54 PF13874.1 EPE30343.1 - 0.018 14.6 3.3 0.018 14.6 2.3 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 zf-MYND PF01753.13 EPE30344.1 - 0.018 14.8 5.2 0.054 13.3 3.6 1.9 1 0 0 1 1 1 0 MYND finger zf-HIT PF04438.11 EPE30344.1 - 2.7 7.7 6.8 9.2 6.0 4.7 1.9 1 0 0 1 1 1 0 HIT zinc finger KH_1 PF00013.24 EPE30345.1 - 1.5e-41 139.8 11.1 7e-15 54.4 0.7 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EPE30345.1 - 8.1e-28 95.5 16.1 2e-09 36.8 0.5 3.9 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EPE30345.1 - 1.1e-11 44.0 2.7 0.018 14.6 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EPE30345.1 - 9.2e-10 38.0 3.2 0.025 14.1 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EPE30345.1 - 1.8e-06 27.6 0.8 0.2 11.4 0.0 3.7 3 0 0 3 3 3 3 NusA-like KH domain SLS PF14611.1 EPE30345.1 - 0.064 12.6 0.0 4.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial inner-membrane-bound regulator DNA_processg_A PF02481.10 EPE30345.1 - 0.089 11.6 0.6 6.5 5.5 0.1 2.3 2 0 0 2 2 2 0 DNA recombination-mediator protein A TIP49 PF06068.8 EPE30346.1 - 1.2e-186 620.2 0.1 1.4e-186 620.0 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EPE30346.1 - 1.7e-11 44.4 0.2 7.3e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPE30346.1 - 2.6e-10 39.7 2.4 1.4e-06 27.5 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EPE30346.1 - 3.2e-05 23.5 0.2 7.8e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EPE30346.1 - 4.2e-05 23.7 0.3 0.28 11.3 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPE30346.1 - 4.3e-05 23.5 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EPE30346.1 - 0.00021 20.7 0.1 0.00054 19.4 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EPE30346.1 - 0.00046 20.1 0.1 0.00099 19.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPE30346.1 - 0.00049 19.8 0.2 0.16 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EPE30346.1 - 0.0013 17.8 0.1 0.0031 16.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EPE30346.1 - 0.0016 17.9 0.1 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF2075 PF09848.4 EPE30346.1 - 0.0075 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 EPE30346.1 - 0.0079 15.3 0.2 0.38 9.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EPE30346.1 - 0.011 15.1 0.3 0.023 14.1 0.2 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 EPE30346.1 - 0.013 15.3 0.0 0.5 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EPE30346.1 - 0.027 13.6 0.3 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.1 EPE30346.1 - 0.027 14.7 0.2 0.09 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.10 EPE30346.1 - 0.047 12.5 0.0 0.085 11.7 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 EPE30346.1 - 0.051 14.3 0.1 0.12 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 EPE30346.1 - 0.11 11.3 0.0 11 4.8 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase HMG_box PF00505.14 EPE30347.1 - 2.6e-22 78.8 0.8 4.7e-22 78.0 0.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPE30347.1 - 4.8e-06 26.8 0.2 9.6e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain AAA PF00004.24 EPE30348.1 - 1.7e-37 128.6 1.3 1.3e-35 122.4 0.0 3.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE30348.1 - 0.00011 22.1 0.1 0.0016 18.4 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EPE30348.1 - 0.00028 20.0 0.0 0.00066 18.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 EPE30348.1 - 0.00052 20.0 0.1 0.34 10.9 0.0 3.3 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_22 PF13401.1 EPE30348.1 - 0.00058 20.0 0.2 0.0097 16.0 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EPE30348.1 - 0.001 18.9 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPE30348.1 - 0.0018 19.0 0.1 0.0063 17.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EPE30348.1 - 0.0063 15.9 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EPE30348.1 - 0.0079 15.9 0.1 0.027 14.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EPE30348.1 - 0.0085 15.8 0.3 7 6.2 0.0 3.4 3 0 0 3 3 3 1 Archaeal ATPase RNA_helicase PF00910.17 EPE30348.1 - 0.012 15.7 0.0 0.21 11.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase TIP49 PF06068.8 EPE30348.1 - 0.017 13.8 0.9 0.055 12.1 0.0 2.0 2 0 0 2 2 2 0 TIP49 C-terminus AAA_19 PF13245.1 EPE30348.1 - 0.022 14.4 0.3 0.022 14.4 0.2 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 EPE30348.1 - 0.024 14.9 0.4 0.11 12.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.16 EPE30348.1 - 0.033 13.3 0.1 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EPE30348.1 - 0.043 13.2 0.1 1.9 7.8 0.1 2.9 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.1 EPE30348.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cu-oxidase_3 PF07732.10 EPE30349.1 - 1.8e-42 143.8 7.9 1.1e-41 141.1 1.7 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPE30349.1 - 3.6e-39 133.4 3.9 8.4e-38 128.9 0.1 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EPE30349.1 - 5.2e-39 133.7 0.2 2.3e-38 131.5 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase Glyco_hydro_114 PF03537.8 EPE30352.1 - 1.9e-23 82.0 0.0 4e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 CBM_1 PF00734.13 EPE30352.1 - 2.2e-08 33.6 11.8 2.2e-08 33.6 8.2 2.5 2 1 0 2 2 2 1 Fungal cellulose binding domain PTH2 PF01981.11 EPE30353.1 - 9.1e-47 157.5 0.5 1.2e-46 157.1 0.4 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF663 PF04950.7 EPE30354.1 - 3.4e-105 351.2 0.0 6.7e-105 350.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EPE30354.1 - 4.9e-19 67.6 0.0 2.1e-18 65.6 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BING4CT PF08149.6 EPE30355.1 - 3.6e-39 132.1 0.0 4.3e-37 125.4 0.0 3.2 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 EPE30355.1 - 4.4e-06 26.3 0.0 0.002 17.9 0.0 4.1 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EPE30355.1 - 0.047 12.4 0.0 0.12 11.0 0.0 1.6 1 1 1 2 2 2 0 Coatomer WD associated region SET PF00856.23 EPE30356.1 - 2.5e-08 34.4 0.1 8e-08 32.7 0.1 1.9 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.11 EPE30357.1 - 2.3e-17 62.7 44.0 4.6e-17 61.7 26.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE30357.1 - 2.1e-05 23.2 8.3 2.1e-05 23.2 5.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2839 PF10999.3 EPE30357.1 - 1.3 9.1 4.3 7.7 6.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) cobW PF02492.14 EPE30358.1 - 1.4e-35 122.3 0.0 1.9e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EPE30358.1 - 2.8e-05 23.0 1.1 0.00033 19.5 0.7 2.0 1 1 0 1 1 1 1 ArgK protein AAA_23 PF13476.1 EPE30358.1 - 0.0093 16.3 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EPE30358.1 - 0.015 15.2 0.0 0.043 13.7 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 EPE30358.1 - 0.032 13.6 0.2 0.069 12.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 EPE30358.1 - 0.051 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TMEM51 PF15345.1 EPE30358.1 - 0.092 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 IstB_IS21 PF01695.12 EPE30358.1 - 0.097 12.0 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein ResIII PF04851.10 EPE30358.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EPE30358.1 - 0.14 11.7 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain SNAP PF14938.1 EPE30359.1 - 1.3e-28 99.9 18.0 2.1e-15 56.6 2.4 2.1 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EPE30359.1 - 0.00036 20.3 19.1 0.00041 20.2 0.7 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPE30359.1 - 0.081 12.5 17.7 0.14 11.7 0.2 4.1 3 2 0 3 3 3 0 TPR repeat TPR_7 PF13176.1 EPE30359.1 - 0.093 12.5 11.6 3.2 7.7 0.0 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPE30359.1 - 4.5 8.1 19.4 15 6.5 0.1 5.9 4 3 2 6 6 6 0 Tetratricopeptide repeat HHH_8 PF14716.1 EPE30359.1 - 5.1 7.3 11.6 2.3 8.4 1.0 3.7 2 1 1 3 3 3 0 Helix-hairpin-helix domain Foie-gras_1 PF11817.3 EPE30359.1 - 6.5 6.1 7.7 0.72 9.2 1.6 2.0 2 1 1 3 3 3 0 Foie gras liver health family 1 DUF1268 PF06896.6 EPE30360.1 - 0.013 15.8 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1268) Glu-tRNAGln PF02686.10 EPE30360.1 - 0.04 13.7 0.2 0.091 12.5 0.1 1.6 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF726 PF05277.7 EPE30361.1 - 3.7e-122 407.5 1.0 5.2e-122 407.0 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 EPE30361.1 - 0.00018 21.8 0.0 0.00039 20.7 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EPE30361.1 - 0.0006 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE30361.1 - 0.089 12.5 0.1 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family TcdA_TcdB_pore PF12920.2 EPE30361.1 - 9 4.0 9.4 15 3.3 6.5 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Mus7 PF09462.5 EPE30363.1 - 2.8e-93 313.8 0.3 4.8e-93 313.0 0.2 1.4 1 0 0 1 1 1 1 Mus7/MMS22 family HET PF06985.6 EPE30364.1 - 7.7e-23 81.1 0.0 1.8e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PilM PF07419.7 EPE30365.1 - 0.018 14.5 1.0 2.6 7.5 0.1 2.3 2 0 0 2 2 2 0 PilM DUF3239 PF11580.3 EPE30365.1 - 0.024 14.6 0.1 5.7 6.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3239) Lactamase_B_2 PF12706.2 EPE30366.1 - 4.5e-22 78.5 0.0 7.2e-22 77.8 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPE30366.1 - 1.9e-12 47.1 0.6 1.3e-11 44.4 0.4 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPE30366.1 - 0.012 15.2 5.2 0.2 11.2 2.2 2.7 2 1 1 3 3 3 0 Metallo-beta-lactamase superfamily Kdo PF06293.9 EPE30368.1 - 4.7e-11 42.1 0.0 7.4e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE30368.1 - 4.6e-09 36.3 0.9 0.00025 20.8 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EPE30368.1 - 3.4e-07 29.6 0.0 4.2e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30368.1 - 0.00013 21.1 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EPE30368.1 - 0.00071 18.9 0.0 0.0016 17.8 0.0 1.5 1 1 0 1 1 1 1 RIO1 family EcKinase PF02958.15 EPE30368.1 - 0.079 12.0 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Aldo_ket_red PF00248.16 EPE30369.1 - 7.3e-09 34.8 0.0 9.7e-09 34.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RunxI PF08504.6 EPE30369.1 - 0.081 13.3 0.2 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Runx inhibition domain Clat_adaptor_s PF01217.15 EPE30370.1 - 1.3e-47 161.0 4.2 9.5e-46 155.0 2.9 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 EPE30371.1 - 1.8e-56 190.7 0.0 2.4e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator polyprenyl_synt PF00348.12 EPE30373.1 - 2.3e-61 206.9 0.0 3e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.6 EPE30374.1 - 1e-89 300.1 0.0 1.2e-89 299.9 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component SKG6 PF08693.5 EPE30375.1 - 0.019 14.2 0.2 0.019 14.2 0.2 1.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Mid2 PF04478.7 EPE30375.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MCM PF00493.18 EPE30377.1 - 1.6e-137 457.7 0.0 2.3e-137 457.2 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EPE30377.1 - 3e-35 121.5 40.8 3e-35 121.5 28.3 2.1 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EPE30377.1 - 1.8e-19 70.4 0.0 4.4e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPE30377.1 - 2.9e-08 33.1 0.3 5.3e-06 25.7 0.0 2.8 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPE30377.1 - 6.1e-06 26.0 0.0 1.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPE30377.1 - 0.0009 18.8 0.0 0.012 15.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPE30377.1 - 0.0026 17.2 0.1 0.011 15.2 0.1 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EPE30377.1 - 0.07 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain zf-TFIIB PF13453.1 EPE30377.1 - 0.35 10.1 1.7 0.81 8.9 1.2 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-UBR PF02207.15 EPE30378.1 - 2.8e-16 58.9 4.1 2.8e-16 58.9 2.9 3.4 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Glyco_hydro_3 PF00933.16 EPE30379.1 - 4.1e-83 278.7 0.0 6.2e-83 278.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE30379.1 - 1.2e-67 227.7 0.0 3.1e-67 226.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE30379.1 - 2e-23 82.0 0.8 5e-23 80.8 0.6 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EPE30379.1 - 5e-12 45.6 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Macro_2 PF14519.1 EPE30379.1 - 0.0072 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain Lipase_GDSL_2 PF13472.1 EPE30379.1 - 0.039 14.0 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Diphtheria_C PF02763.9 EPE30379.1 - 0.05 13.0 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Diphtheria toxin, C domain IDO PF01231.13 EPE30380.1 - 2.3e-49 167.9 0.0 3e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CAP PF00188.21 EPE30381.1 - 1.7e-21 76.9 0.4 3.2e-21 76.1 0.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SOG2 PF10428.4 EPE30381.1 - 0.26 9.8 3.6 0.32 9.5 2.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Trypan_PARP PF05887.6 EPE30381.1 - 0.63 9.8 6.3 1.1 9.0 4.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4576 PF15144.1 EPE30381.1 - 3.9 7.1 5.4 7.5 6.2 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Cu-oxidase_3 PF07732.10 EPE30382.1 - 1.6e-44 150.4 2.5 3e-44 149.5 0.5 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPE30382.1 - 2.4e-38 130.7 7.4 1e-36 125.5 0.3 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EPE30382.1 - 3.3e-34 118.0 0.4 1.9e-32 112.3 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase Aldo_ket_red PF00248.16 EPE30383.1 - 1.4e-56 191.3 0.0 1.6e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SNARE PF05739.14 EPE30384.1 - 3.9e-14 52.0 3.5 3.9e-14 52.0 2.4 2.4 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EPE30384.1 - 5.9e-07 29.6 9.8 5.9e-07 29.6 6.8 2.1 2 1 0 2 2 2 1 Syntaxin ETRAMP PF09716.5 EPE30384.1 - 0.0026 17.6 1.3 0.0042 17.0 0.0 2.0 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Use1 PF09753.4 EPE30384.1 - 0.0028 17.1 7.6 0.0045 16.4 5.3 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 Herpes_US9 PF06072.6 EPE30384.1 - 0.016 15.0 0.3 0.06 13.1 0.1 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 PBP1_TM PF14812.1 EPE30384.1 - 0.056 13.7 0.1 0.056 13.7 0.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2077 PF09850.4 EPE30384.1 - 0.13 11.6 0.0 0.13 11.6 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) Allexi_40kDa PF05549.6 EPE30384.1 - 0.13 11.4 7.1 0.074 12.3 1.7 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Utp12 PF04003.7 EPE30384.1 - 0.14 12.0 1.1 0.44 10.4 0.3 2.0 2 0 0 2 2 2 0 Dip2/Utp12 Family SPT16 PF08644.6 EPE30384.1 - 0.28 11.0 4.0 0.18 11.6 0.3 2.1 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF3708 PF12501.3 EPE30384.1 - 1.6 8.5 10.3 0.14 12.0 0.4 2.8 1 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter COPIIcoated_ERV PF07970.7 EPE30385.1 - 3.8e-37 128.0 0.1 5.4e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EPE30385.1 - 1.2e-21 76.4 0.0 2.5e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1996 PF09362.5 EPE30386.1 - 4.5e-81 271.9 0.9 5.7e-81 271.6 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EPE30386.1 - 6.2e-06 26.0 0.0 6.2e-06 26.0 0.0 2.7 3 0 0 3 3 3 1 WSC domain PhoD PF09423.5 EPE30387.1 - 5.2e-159 529.6 3.3 6.2e-159 529.3 2.3 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PgaD PF13994.1 EPE30388.1 - 0.00089 18.7 0.1 0.001 18.5 0.1 1.1 1 0 0 1 1 1 1 PgaD-like protein Sigma_reg_N PF13800.1 EPE30388.1 - 0.055 13.5 1.0 0.062 13.3 0.7 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF4307 PF14155.1 EPE30388.1 - 0.13 12.0 0.4 0.16 11.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) DUF3328 PF11807.3 EPE30388.1 - 0.14 11.8 0.1 0.15 11.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) TRP PF06011.7 EPE30388.1 - 0.16 10.5 1.2 0.16 10.5 0.8 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF912 PF06024.7 EPE30388.1 - 6 6.9 5.3 6 6.9 3.4 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MFS_1 PF07690.11 EPE30389.1 - 9.3e-30 103.5 43.8 5.1e-29 101.0 27.8 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE30389.1 - 1e-10 40.7 5.4 1e-10 40.7 3.7 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EPE30389.1 - 5.5e-07 28.1 9.3 5.5e-07 28.1 6.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF43 PF01861.11 EPE30389.1 - 0.0031 16.5 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Iron_permease PF04120.7 EPE30389.1 - 1 8.9 6.4 0.56 9.7 0.0 2.9 2 1 1 3 3 3 0 Low affinity iron permease p450 PF00067.17 EPE30390.1 - 3.3e-49 167.6 0.0 4.3e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 EPE30391.1 - 0.00049 19.9 9.9 0.00094 19.0 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 EPE30392.1 - 1.5e-31 109.5 2.8 2.5e-31 108.8 2.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EPE30392.1 - 5.3e-21 74.2 0.1 1.3e-20 72.9 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EPE30392.1 - 2.6e-16 58.8 0.7 6e-16 57.6 0.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EPE30392.1 - 4.7e-11 43.2 0.1 1.1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EPE30392.1 - 0.00023 21.4 0.1 0.00047 20.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain A_deaminase PF00962.17 EPE30393.1 - 1.3e-47 162.3 0.0 1.8e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase ATG2_CAD PF13329.1 EPE30394.1 - 5.6e-37 126.7 0.0 1.5e-36 125.3 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EPE30394.1 - 5.4e-19 68.1 0.0 1.6e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 EPE30394.1 - 0.00017 21.1 0.2 0.00066 19.2 0.1 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ubiquitin PF00240.18 EPE30395.1 - 1.5e-11 43.5 0.0 4.7e-11 41.9 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin family zf-AN1 PF01428.11 EPE30395.1 - 3.4e-10 39.6 11.6 6.8e-10 38.6 8.1 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.3 EPE30395.1 - 2.5e-09 36.6 0.0 3.8e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 EPE30395.1 - 0.001 18.7 0.2 0.0016 18.1 0.1 1.2 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 EPE30395.1 - 0.0035 17.4 0.0 0.0041 17.2 0.0 1.3 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain YukD PF08817.5 EPE30395.1 - 0.079 13.5 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD ADH_N PF08240.7 EPE30396.1 - 9e-28 96.2 1.9 9e-28 96.2 1.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE30396.1 - 4.5e-18 65.0 0.2 8e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EPE30396.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FtsJ PF01728.14 EPE30396.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase 2-Hacid_dh_C PF02826.14 EPE30396.1 - 0.13 11.3 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 EPE30397.1 - 4e-18 66.1 0.1 4.6e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE30397.1 - 8.4e-10 38.5 0.6 1.3e-09 37.9 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE30397.1 - 7e-05 22.4 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold PrsW-protease PF13367.1 EPE30397.1 - 0.038 13.1 0.1 0.054 12.6 0.1 1.2 1 0 0 1 1 1 0 Protease prsW family Ser_hydrolase PF06821.8 EPE30397.1 - 0.051 13.1 0.2 0.13 11.8 0.1 1.6 1 1 1 2 2 2 0 Serine hydrolase Abhydrolase_8 PF06259.7 EPE30397.1 - 0.19 11.2 1.5 0.3 10.5 1.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase CMD PF02627.15 EPE30398.1 - 1.8e-09 37.2 0.0 1.2e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family GNVR PF13807.1 EPE30398.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase ATP-synt_C PF00137.16 EPE30399.1 - 2.9e-32 110.3 30.1 1e-18 66.9 8.6 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EPE30399.1 - 0.15 11.6 4.7 0.037 13.5 0.7 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Ribosomal_L7Ae PF01248.21 EPE30400.1 - 4.9e-24 83.6 0.1 5.6e-24 83.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EPE30400.1 - 0.00035 20.4 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EPE30400.1 - 0.027 14.2 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF3115 PF11312.3 EPE30401.1 - 6.5e-95 317.6 0.0 7.6e-95 317.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) HATPase_c PF02518.21 EPE30403.1 - 1.3e-27 95.6 0.0 6.4e-27 93.4 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE30403.1 - 6.3e-25 87.3 0.1 1.3e-24 86.3 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EPE30403.1 - 8.2e-14 51.3 0.0 1.6e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EPE30403.1 - 5.3e-05 23.3 0.0 0.27 11.4 0.0 2.7 2 0 0 2 2 2 2 HAMP domain Syja_N PF02383.13 EPE30404.1 - 2.2e-94 315.7 0.0 3.5e-94 315.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EPE30404.1 - 7.4e-38 128.4 0.0 1.3e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase bZIP_1 PF00170.16 EPE30406.1 - 9e-11 41.5 5.0 1.9e-10 40.5 3.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPE30406.1 - 0.00034 20.3 7.8 0.00034 20.3 5.4 2.7 2 1 1 3 3 3 1 Basic region leucine zipper HALZ PF02183.13 EPE30406.1 - 0.019 14.6 0.7 0.038 13.7 0.5 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper IncA PF04156.9 EPE30406.1 - 0.073 12.6 6.7 0.098 12.2 4.6 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EPE30406.1 - 0.19 9.5 2.8 0.23 9.2 2.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zwint PF15556.1 EPE30406.1 - 0.22 10.7 4.8 0.29 10.3 3.3 1.1 1 0 0 1 1 1 0 ZW10 interactor DUF972 PF06156.8 EPE30406.1 - 0.3 11.4 2.7 0.4 11.0 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF724 PF05266.9 EPE30406.1 - 0.3 10.6 3.1 0.41 10.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GAS PF13851.1 EPE30406.1 - 0.37 9.9 4.7 0.48 9.5 3.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EPE30406.1 - 0.43 10.0 2.0 13 5.3 0.2 2.5 1 1 1 2 2 2 0 Septum formation initiator KLRAQ PF10205.4 EPE30406.1 - 0.6 10.1 6.7 0.99 9.4 4.5 1.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein FAM75 PF14650.1 EPE30406.1 - 0.87 8.9 6.6 1.2 8.4 4.5 1.1 1 0 0 1 1 1 0 FAM75 family APG6 PF04111.7 EPE30406.1 - 0.93 8.4 5.5 1.2 8.1 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_Maf PF03131.12 EPE30406.1 - 1.6 9.0 16.4 4.2 7.7 11.1 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor Transketolase_N PF00456.16 EPE30407.1 - 1.9e-147 490.4 0.2 2.7e-147 489.9 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EPE30407.1 - 4.5e-46 156.5 0.0 6.5e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EPE30407.1 - 3.1e-12 46.5 0.0 6.5e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EPE30407.1 - 5.3e-06 25.5 0.1 2.2e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Filament PF00038.16 EPE30409.1 - 0.00032 20.2 31.7 0.00032 20.2 22.0 3.8 2 1 0 3 3 3 1 Intermediate filament protein ATG16 PF08614.6 EPE30409.1 - 0.092 12.5 66.0 0.12 12.1 9.6 5.2 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EPE30409.1 - 0.69 9.0 14.0 0.78 8.8 3.4 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein zf-C2H2_4 PF13894.1 EPE30410.1 - 0.00012 22.1 13.5 1.1 9.6 0.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE30410.1 - 0.0018 18.5 14.3 0.2 12.0 1.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type MFS_1 PF07690.11 EPE30411.1 - 2.3e-30 105.5 38.7 2.3e-30 105.5 26.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1616 PF07760.6 EPE30411.1 - 0.66 9.0 5.9 0.2 10.7 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1616) DUF427 PF04248.7 EPE30412.1 - 1.6e-36 123.8 0.4 6.5e-29 99.4 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF427) 6PGD PF00393.14 EPE30413.1 - 6.1e-70 235.7 0.3 7.3e-70 235.4 0.2 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EPE30413.1 - 2.3e-35 121.8 0.1 5.1e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EPE30413.1 - 7.4e-06 25.7 0.1 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EPE30413.1 - 3.1e-05 24.3 0.0 8.7e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EPE30413.1 - 0.00066 19.4 0.0 0.002 17.8 0.0 1.9 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EPE30413.1 - 0.0015 17.9 0.2 0.029 13.7 0.1 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EPE30413.1 - 0.0039 16.6 0.0 0.0095 15.3 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_11 PF14833.1 EPE30413.1 - 0.037 14.0 0.1 0.098 12.7 0.0 1.8 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GFO_IDH_MocA PF01408.17 EPE30413.1 - 0.06 13.8 0.1 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold SET PF00856.23 EPE30414.1 - 0.11 12.8 0.2 0.34 11.2 0.0 1.8 2 1 0 2 2 2 0 SET domain AMP-binding PF00501.23 EPE30416.1 - 6.7e-75 252.0 0.0 1e-74 251.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPE30416.1 - 2.7e-67 226.3 0.0 4.3e-67 225.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EPE30416.1 - 6e-11 42.2 0.0 1.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE30416.1 - 1.1e-09 37.4 0.0 3.1e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EPE30416.1 - 4.7e-09 36.3 0.0 8.7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPE30416.1 - 6.6e-07 30.1 0.0 6.3e-06 27.0 0.0 2.7 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain DUF1667 PF07892.6 EPE30416.1 - 0.038 13.6 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1667) Glyco_hydro_15 PF00723.16 EPE30417.1 - 4e-106 355.2 0.1 4.8e-106 354.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EPE30417.1 - 5.1e-35 118.9 0.2 1.3e-34 117.6 0.1 1.8 1 0 0 1 1 1 1 Starch binding domain SART-1 PF03343.8 EPE30418.1 - 4.1e-173 577.0 65.4 4.7e-173 576.8 45.4 1.0 1 0 0 1 1 1 1 SART-1 family HeLo PF14479.1 EPE30419.1 - 3.9e-24 85.5 0.1 1.7e-23 83.4 0.0 2.0 1 1 0 1 1 1 1 Prion-inhibition and propagation F-box PF00646.28 EPE30420.1 - 0.32 10.6 2.4 14 5.4 0.1 2.6 2 0 0 2 2 2 0 F-box domain DUF676 PF05057.9 EPE30423.1 - 2.5e-55 187.1 0.0 3.6e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EPE30423.1 - 5.5e-08 32.6 0.0 9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EPE30423.1 - 0.00018 21.1 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EPE30423.1 - 0.00025 21.0 0.0 0.0012 18.8 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPE30423.1 - 0.0033 17.0 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 EPE30423.1 - 0.059 12.4 0.4 3.9 6.4 0.0 2.6 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.11 EPE30423.1 - 0.16 11.4 0.3 6.2 6.2 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 EPE30423.1 - 0.17 11.1 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family RNase_T PF00929.19 EPE30424.1 - 2.4e-09 37.6 0.0 4.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease CHORD PF04968.7 EPE30424.1 - 0.3 11.3 8.1 0.76 10.0 1.5 2.7 1 1 1 2 2 2 0 CHORD Rep_fac_C PF08542.6 EPE30425.1 - 3.9e-21 74.8 0.0 9.7e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPE30425.1 - 7.9e-12 45.1 0.0 1.5e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EPE30425.1 - 1.7e-06 28.2 0.2 3.9e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE30425.1 - 1.2e-05 25.4 1.3 0.00047 20.2 0.3 3.2 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.10 EPE30425.1 - 0.00051 18.8 0.0 0.00077 18.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EPE30425.1 - 0.0014 18.6 0.9 0.033 14.1 0.5 2.5 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EPE30425.1 - 0.005 16.9 0.2 0.15 12.1 0.2 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 EPE30425.1 - 0.0062 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2861 PF11060.3 EPE30425.1 - 0.0091 15.3 0.1 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2861) ABC_tran PF00005.22 EPE30425.1 - 0.0096 16.2 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 EPE30425.1 - 0.032 13.9 0.1 0.077 12.6 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase T4SS-DNA_transf PF02534.9 EPE30425.1 - 0.043 12.3 0.1 0.1 11.1 0.0 1.5 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer DNA_pol3_delta PF06144.8 EPE30425.1 - 0.056 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit SNF2_N PF00176.18 EPE30425.1 - 0.074 11.8 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_10 PF12846.2 EPE30425.1 - 0.14 11.5 0.1 2.4 7.4 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 EPE30425.1 - 0.14 11.7 0.0 0.92 9.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EPE30425.1 - 0.17 11.6 0.6 0.69 9.6 0.4 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AATase PF07247.7 EPE30426.1 - 4.3e-15 55.2 0.0 1.2e-12 47.2 0.0 2.3 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EPE30426.1 - 2e-06 26.8 1.1 5.9e-05 22.0 0.7 2.2 1 1 0 1 1 1 1 Condensation domain HTH_42 PF06224.7 EPE30427.1 - 0.0096 15.2 1.0 0.011 15.0 0.7 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain COG2 PF06148.6 EPE30427.1 - 0.039 13.8 2.5 0.057 13.2 1.7 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Pox_A_type_inc PF04508.7 EPE30427.1 - 2.4 8.1 8.9 3.6 7.6 0.0 3.8 3 2 0 3 3 3 0 Viral A-type inclusion protein repeat alpha-hel2 PF14456.1 EPE30429.1 - 0.027 13.2 0.1 0.047 12.4 0.1 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 Pyridox_oxidase PF01243.15 EPE30430.1 - 0.047 13.7 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase VWA_2 PF13519.1 EPE30431.1 - 9e-17 61.7 0.5 9e-17 61.7 0.4 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EPE30431.1 - 8.1e-11 41.9 0.7 1.3e-10 41.3 0.1 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.1 EPE30431.1 - 2.8e-05 23.8 0.1 0.002 17.8 0.0 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EPE30431.1 - 0.0023 17.0 0.2 0.0054 15.9 0.1 1.5 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2201 PF09967.4 EPE30431.1 - 0.055 13.4 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 VWA-like domain (DUF2201) DUF1233 PF06806.7 EPE30432.1 - 0.12 11.9 0.2 16 5.0 0.1 2.3 2 0 0 2 2 2 0 Putative excisionase (DUF1233) SDA1 PF05285.7 EPE30433.1 - 0.00091 18.6 2.3 0.0014 18.0 1.6 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.9 EPE30433.1 - 0.029 12.4 1.2 0.037 12.0 0.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CCDC14 PF15254.1 EPE30434.1 - 0.016 13.6 3.4 0.02 13.2 2.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Cuticle_3 PF11018.3 EPE30434.1 - 0.023 14.8 1.5 0.037 14.1 1.0 1.3 1 0 0 1 1 1 0 Pupal cuticle protein C1 OTT_1508_deam PF14441.1 EPE30438.1 - 9.6e-11 41.6 0.7 9.6e-11 41.6 0.5 2.1 2 0 0 2 2 2 1 OTT_1508-like deaminase zf-MYND PF01753.13 EPE30438.1 - 2.2e-06 27.4 15.0 5.1e-06 26.2 10.4 1.7 1 0 0 1 1 1 1 MYND finger ACCA PF03255.9 EPE30438.1 - 0.00082 18.9 1.5 0.0074 15.8 0.0 3.1 4 0 0 4 4 4 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CIDE-N PF02017.10 EPE30438.1 - 2.2 8.1 4.8 19 5.0 0.0 3.2 3 0 0 3 3 3 0 CIDE-N domain zf-CCHC PF00098.18 EPE30439.1 - 0.34 10.9 34.4 0.058 13.3 2.6 4.3 4 0 0 4 4 4 0 Zinc knuckle ORMDL PF04061.9 EPE30440.1 - 6.2e-61 203.8 4.0 7e-61 203.7 2.8 1.0 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 EPE30440.1 - 0.11 12.1 1.7 0.12 12.0 0.4 1.6 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) MFS_1 PF07690.11 EPE30441.1 - 2.1e-37 128.6 39.6 2.1e-37 128.6 27.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PAP2_C PF14360.1 EPE30441.1 - 0.07 13.4 0.4 0.07 13.4 0.3 3.2 3 0 0 3 3 3 0 PAP2 superfamily C-terminal GP41 PF00517.12 EPE30441.1 - 9.6 5.7 5.8 24 4.4 0.1 2.8 3 0 0 3 3 3 0 Retroviral envelope protein Ank_2 PF12796.2 EPE30442.1 - 6.1e-26 90.5 0.3 2.4e-11 43.7 0.1 3.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE30442.1 - 2.9e-21 74.1 3.1 2.4e-06 27.0 0.1 6.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.1 EPE30442.1 - 5.2e-16 57.1 5.8 0.0016 18.4 0.2 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 EPE30442.1 - 2.4e-13 50.2 1.3 1.4e-05 25.4 0.2 5.5 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE30442.1 - 2.6e-08 33.8 0.4 0.0014 18.7 0.0 4.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) F-box-like PF12937.2 EPE30442.1 - 0.031 14.0 0.3 0.068 12.9 0.2 1.6 1 0 0 1 1 1 0 F-box-like RTA1 PF04479.8 EPE30443.1 - 3e-32 111.9 9.5 4.9e-32 111.2 6.6 1.3 1 0 0 1 1 1 1 RTA1 like protein Caveolin PF01146.12 EPE30443.1 - 0.072 12.6 2.6 0.25 10.8 1.8 2.0 1 0 0 1 1 1 0 Caveolin DUF2207 PF09972.4 EPE30443.1 - 0.076 11.5 7.7 0.69 8.4 0.6 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ABC2_membrane_2 PF12679.2 EPE30443.1 - 3.6 6.3 16.0 30 3.3 11.1 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein Vps39_1 PF10366.4 EPE30444.1 - 4.8e-34 116.6 0.0 3.4e-33 113.8 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EPE30444.1 - 9.1e-31 106.2 0.1 3.3e-30 104.4 0.0 2.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EPE30444.1 - 7.2e-20 71.5 0.0 5.9e-19 68.5 0.0 2.1 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 EPE30444.1 - 9.7e-05 21.9 3.7 0.00014 21.4 0.7 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS Apc3 PF12895.2 EPE30444.1 - 0.092 12.9 3.3 0.43 10.7 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EPE30444.1 - 0.11 13.1 0.8 26 5.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Gon7 PF08738.5 EPE30445.1 - 6.9e-16 58.1 8.5 1.4e-14 53.9 5.9 2.0 1 1 0 1 1 1 1 Gon7 family BTV_NS2 PF04514.7 EPE30445.1 - 0.16 10.8 3.1 0.16 10.8 2.2 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AATF-Che1 PF13339.1 EPE30445.1 - 0.17 12.0 2.2 0.19 11.8 1.5 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Hamartin PF04388.7 EPE30445.1 - 0.19 10.3 1.6 0.19 10.3 1.1 1.0 1 0 0 1 1 1 0 Hamartin protein HbrB PF08539.6 EPE30446.1 - 2.3e-54 183.4 0.0 3.4e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 HbrB-like TMEM171 PF15471.1 EPE30446.1 - 0.13 11.0 1.9 0.35 9.6 1.3 1.7 1 0 0 1 1 1 0 Transmembrane protein family 171 SelP_N PF04592.9 EPE30446.1 - 6.2 6.1 10.6 4.9 6.4 2.5 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF4448 PF14610.1 EPE30447.1 - 0.0025 17.3 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Mid2 PF04478.7 EPE30447.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM51 PF15345.1 EPE30447.1 - 0.024 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1191 PF06697.7 EPE30447.1 - 0.025 13.3 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 EPE30447.1 - 0.34 10.2 2.0 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain CFEM PF05730.6 EPE30447.1 - 6.4 6.6 14.7 29 4.5 10.2 2.1 1 1 0 1 1 1 0 CFEM domain Bac_luciferase PF00296.15 EPE30448.1 - 2.2e-58 197.8 0.2 3.2e-58 197.2 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Pyr_redox_2 PF07992.9 EPE30449.1 - 4.9e-30 104.9 0.9 7.4e-30 104.3 0.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE30449.1 - 4.2e-14 52.7 3.4 3.9e-13 49.6 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EPE30449.1 - 1.3e-12 47.0 0.0 3.8e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EPE30449.1 - 3.6e-09 36.9 0.0 9.3e-05 22.5 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EPE30449.1 - 3.4e-06 27.2 0.0 8.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.1 EPE30449.1 - 0.011 15.5 2.9 0.57 9.9 0.0 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EPE30449.1 - 0.011 15.9 0.8 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF1188 PF06690.6 EPE30449.1 - 0.044 12.9 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Fib_alpha PF08702.5 EPE30450.1 - 1.9 8.5 14.8 0.35 11.0 4.6 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EPE30450.1 - 3.4 7.2 36.6 16 4.9 0.0 3.3 2 1 1 3 3 3 0 IncA protein DUF2937 PF11157.3 EPE30450.1 - 6.1 6.1 7.5 18 4.6 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) GAS PF13851.1 EPE30450.1 - 6.5 5.8 28.1 3.7 6.6 7.1 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.15 EPE30450.1 - 7.4 5.5 36.9 72 2.3 24.8 2.3 1 1 0 1 1 1 0 Tropomyosin Mgr1 PF08602.5 EPE30450.1 - 7.9 5.3 11.5 12 4.7 3.4 2.5 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Ank_2 PF12796.2 EPE30452.1 - 2.5e-07 30.9 0.0 6.7e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE30452.1 - 6.2e-07 28.9 0.8 4.1e-06 26.3 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EPE30452.1 - 1.3e-06 28.4 0.1 4.1e-06 26.8 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE30452.1 - 1.5e-05 25.4 0.2 7.7e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE30452.1 - 0.00069 19.6 0.1 0.0044 17.1 0.1 2.4 1 0 0 1 1 1 1 Ankyrin repeat p450 PF00067.17 EPE30453.1 - 2e-52 178.2 0.0 2.8e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 EPE30454.1 - 3.8e-54 183.8 0.0 3.2e-27 95.4 0.0 2.0 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE30454.1 - 7.9e-32 110.5 0.0 1.4e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPE30454.1 - 5.8e-09 35.3 0.1 1.9e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE30454.1 - 4.9e-06 26.4 0.2 1.5e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE30454.1 - 0.00056 18.8 0.9 0.039 12.7 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 EPE30454.1 - 0.0092 15.0 0.1 0.02 14.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EPE30454.1 - 0.014 15.3 0.1 0.057 13.2 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE30454.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPE30454.1 - 0.054 13.5 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE30454.1 - 0.055 11.9 0.0 0.1 11.0 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EPE30454.1 - 0.19 12.1 2.4 0.21 12.0 0.0 2.3 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Oxysterol_BP PF01237.13 EPE30455.1 - 2.2e-80 269.8 0.0 2.8e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein DUF658 PF04936.7 EPE30455.1 - 0.00053 19.8 0.7 0.00093 19.0 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF658) CsbD PF05532.7 EPE30456.1 - 2.7e-15 55.7 28.2 2.6e-10 39.7 4.1 3.1 2 1 1 3 3 3 3 CsbD-like UPF0444 PF15475.1 EPE30456.1 - 0.051 13.6 9.6 0.59 10.2 0.4 2.9 3 1 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 Band_7 PF01145.20 EPE30457.1 - 4.1e-25 88.7 6.4 5e-25 88.4 4.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 EPE30457.1 - 0.021 14.1 0.8 0.034 13.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) UcrQ PF02939.11 EPE30458.1 - 8.8e-29 99.1 0.1 1e-28 98.9 0.1 1.0 1 0 0 1 1 1 1 UcrQ family Ribosomal_L7Ae PF01248.21 EPE30459.1 - 6.5e-23 80.0 0.5 1.9e-22 78.5 0.4 1.8 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Anti-adapt_IraP PF10796.4 EPE30459.1 - 0.049 14.0 1.2 0.16 12.3 0.1 2.3 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein Sox_N PF12444.3 EPE30459.1 - 7.8 7.6 7.9 5.4 8.1 4.0 1.9 2 0 0 2 2 2 0 Sox developmental protein N terminal DHDPS PF00701.17 EPE30462.1 - 4.3e-35 120.7 0.0 5.7e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Lys-AminoMut_A PF09043.6 EPE30462.1 - 0.19 9.8 0.0 0.36 8.8 0.0 1.4 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase alpha subunit Amidohydro_2 PF04909.9 EPE30463.1 - 2.9e-20 72.9 0.0 3.8e-20 72.5 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase HET PF06985.6 EPE30464.1 - 5.3e-21 75.2 6.5 1.7e-19 70.3 0.6 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Hydrolase_6 PF13344.1 EPE30465.1 - 1.8e-23 82.3 0.0 3.5e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE30465.1 - 4.8e-12 45.4 0.0 2.1e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EPE30465.1 - 0.0053 16.9 0.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPE30465.1 - 0.013 15.8 0.0 0.043 14.2 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sec3_C PF09763.4 EPE30467.1 - 0.41 8.7 5.1 0.44 8.6 3.5 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF4551 PF15087.1 EPE30467.1 - 1.5 7.1 11.9 2.4 6.4 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RP-C_C PF11800.3 EPE30467.1 - 3.4 7.3 6.3 5.2 6.7 4.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Glyco_hydro_63 PF03200.11 EPE30468.1 - 5.1e-09 34.5 4.0 5.2e-07 27.9 0.6 3.3 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase Nop PF01798.13 EPE30468.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative snoRNA binding domain OSCP PF00213.13 EPE30469.1 - 1.6e-43 148.5 1.1 1.9e-43 148.2 0.7 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Mob1_phocein PF03637.12 EPE30470.1 - 3.6e-72 241.6 0.0 5.3e-72 241.1 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Rgp1 PF08737.5 EPE30471.1 - 3.3e-130 434.8 0.0 7.9e-130 433.6 0.0 1.6 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 EPE30471.1 - 0.0095 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EPE30471.1 - 0.012 15.7 0.0 0.082 13.0 0.0 2.4 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain vMSA PF00695.14 EPE30471.1 - 1.8 7.7 2.9 3.2 6.8 2.0 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus SprT-like PF10263.4 EPE30472.1 - 0.0077 15.8 0.0 0.0077 15.8 0.0 1.1 1 0 0 1 1 1 1 SprT-like family SprT-like PF10263.4 EPE30473.1 - 0.00092 18.8 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.1 EPE30473.1 - 0.079 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Effector protein SAM_2 PF07647.12 EPE30473.1 - 0.079 12.8 0.2 8.5 6.3 0.0 2.7 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Peptidase_M27 PF01742.12 EPE30473.1 - 0.19 10.5 2.6 4 6.2 0.0 2.1 1 1 1 2 2 2 0 Clostridial neurotoxin zinc protease DUF3896 PF13035.1 EPE30473.1 - 0.27 11.2 2.9 0.37 10.8 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) SprT-like PF10263.4 EPE30474.1 - 0.0016 18.1 0.1 0.0041 16.7 0.1 1.7 1 1 0 1 1 1 1 SprT-like family Toxin_7 PF05980.7 EPE30475.1 - 0.015 15.3 6.6 0.022 14.7 4.6 1.3 1 0 0 1 1 1 0 Toxin 7 Atracotoxin PF05353.6 EPE30475.1 - 0.38 10.6 6.9 0.63 9.9 4.8 1.3 1 0 0 1 1 1 0 Delta Atracotoxin Toxin_12 PF07740.7 EPE30475.1 - 0.61 10.6 9.2 1.1 9.8 6.4 1.5 1 1 0 1 1 1 0 Ion channel inhibitory toxin DIM1 PF02966.11 EPE30476.1 - 7.2e-70 232.6 0.1 9.1e-70 232.3 0.1 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EPE30476.1 - 0.041 13.9 0.2 0.1 12.7 0.1 1.7 2 1 0 2 2 2 0 Thioredoxin-like TnpW PF14202.1 EPE30477.1 - 0.12 12.0 0.5 0.24 11.0 0.1 1.8 1 1 1 2 2 2 0 Transposon-encoded protein TnpW LIM_bind PF01803.11 EPE30478.1 - 1.4e-73 246.9 1.5 1.4e-73 246.9 1.1 4.5 3 1 1 4 4 4 1 LIM-domain binding protein HET PF06985.6 EPE30479.1 - 2.9e-33 114.9 1.0 4.3e-33 114.4 0.7 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 EPE30480.1 - 2.9e-17 62.6 0.0 2.2e-15 56.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30480.1 - 8.5e-08 31.5 0.0 2e-06 27.0 0.0 2.6 2 1 1 3 3 3 1 Protein tyrosine kinase Ank_2 PF12796.2 EPE30481.1 - 2.7e-78 258.3 15.9 6e-22 77.7 0.1 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE30481.1 - 1.6e-55 184.5 12.6 3e-09 37.1 0.0 5.7 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.25 EPE30481.1 - 4.6e-54 177.6 13.3 4e-07 29.5 0.2 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 EPE30481.1 - 6.8e-46 149.6 3.6 8.7e-06 25.4 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 EPE30481.1 - 3.6e-40 135.0 12.9 3.7e-09 36.5 1.0 7.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 EPE30481.1 - 0.0094 15.4 0.0 0.78 9.1 0.0 2.6 2 1 1 3 3 3 1 Shigella flexneri OspC protein SelA PF03841.8 EPE30481.1 - 0.0098 14.6 0.1 0.016 13.9 0.1 1.4 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Arg_repressor PF01316.16 EPE30481.1 - 0.051 13.1 1.1 15 5.2 0.1 4.1 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain BRX_N PF13713.1 EPE30481.1 - 0.067 12.6 0.4 0.18 11.2 0.3 1.7 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain DUF2384 PF09722.5 EPE30481.1 - 0.07 12.9 0.2 5.2 7.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) CholecysA-Rec_N PF09193.5 EPE30481.1 - 0.15 11.9 0.1 3.9 7.4 0.0 3.2 5 0 0 5 5 5 0 Cholecystokinin A receptor, N-terminal FA PF08736.6 EPE30481.1 - 1.5 8.6 8.3 4.2 7.2 0.0 4.4 6 0 0 6 6 6 0 FERM adjacent (FA) WW PF00397.21 EPE30483.1 - 6e-17 61.1 8.4 5.1e-06 26.2 0.0 4.1 4 0 0 4 4 4 3 WW domain DUF4585 PF15232.1 EPE30483.1 - 0.077 12.8 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4585) dsrm PF00035.20 EPE30484.1 - 1.7 9.2 4.5 3 8.4 0.4 2.3 2 0 0 2 2 2 0 Double-stranded RNA binding motif RyR PF02026.11 EPE30485.1 - 0.3 11.1 1.9 0.44 10.6 0.3 1.9 2 0 0 2 2 2 0 RyR domain Cerato-platanin PF07249.7 EPE30486.1 - 1.1e-53 180.2 2.3 1.3e-53 180.0 1.6 1.0 1 0 0 1 1 1 1 Cerato-platanin 2OG-FeII_Oxy_3 PF13640.1 EPE30487.1 - 0.0007 20.0 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.6 EPE30488.1 - 1.7e-28 99.4 8.2 3.1e-28 98.6 5.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4050 PF13259.1 EPE30491.1 - 1e-35 122.2 0.3 2.6e-34 117.7 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4050) HET PF06985.6 EPE30492.1 - 6.4e-23 81.4 2.2 1.4e-22 80.3 0.0 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) JmjC PF02373.17 EPE30493.1 - 0.077 13.2 0.2 3.8 7.7 0.1 2.6 1 1 0 1 1 1 0 JmjC domain, hydroxylase Mitofilin PF09731.4 EPE30493.1 - 1 7.9 8.6 1.3 7.6 5.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SRP-alpha_N PF04086.8 EPE30493.1 - 2.5 7.4 8.6 3.9 6.7 6.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pex14_N PF04695.8 EPE30496.1 - 2.4e-27 95.6 0.2 2.4e-27 95.6 0.1 2.7 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DTHCT PF08070.6 EPE30497.1 - 0.32 11.6 3.8 0.43 11.2 2.6 1.2 1 0 0 1 1 1 0 DTHCT (NUC029) region PAPA-1 PF04795.7 EPE30498.1 - 2.2e-27 95.5 2.3 2.2e-27 95.5 1.6 3.5 4 1 0 4 4 4 1 PAPA-1-like conserved region RNA_pol_3_Rpc31 PF11705.3 EPE30498.1 - 8.1 6.3 45.4 0.13 12.1 6.7 3.2 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Myb_DNA-bind_6 PF13921.1 EPE30501.1 - 0.00026 21.0 1.2 0.00069 19.6 0.3 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EPE30501.1 - 0.0014 18.7 0.8 0.0023 17.9 0.5 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EPE30501.1 - 0.0014 18.4 1.5 0.0024 17.7 1.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EPE30501.1 - 0.011 16.2 0.2 0.019 15.5 0.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 EPE30501.1 - 0.037 14.0 1.0 6.9 6.8 0.1 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPE30502.1 - 0.00012 22.0 0.8 0.00024 21.1 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EPE30502.1 - 0.0021 18.1 0.1 0.0063 16.6 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain 4HBT PF03061.17 EPE30507.1 - 6.4e-15 55.0 0.0 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EPE30507.1 - 0.00019 21.8 0.0 0.00037 20.9 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily HMGL-like PF00682.14 EPE30508.1 - 2.3e-38 132.1 0.0 4.7e-38 131.1 0.0 1.5 1 1 0 1 1 1 1 HMGL-like PAN_2 PF08276.6 EPE30509.1 - 0.00015 21.5 0.8 0.00043 20.0 0.4 2.0 1 1 0 1 1 1 1 PAN-like domain PAN_1 PF00024.21 EPE30509.1 - 0.002 17.8 1.8 0.004 16.8 0.8 1.9 1 1 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EPE30509.1 - 0.0026 17.4 0.3 0.0087 15.7 0.2 1.9 1 0 0 1 1 1 1 PAN domain HET PF06985.6 EPE30510.1 - 1.6e-24 86.6 3.7 2.4e-24 86.0 2.5 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1647 PF07801.6 EPE30510.1 - 0.045 13.2 0.1 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) Epimerase PF01370.16 EPE30511.1 - 1.4e-14 54.1 0.0 4.5e-14 52.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE30511.1 - 3.7e-12 46.6 0.0 4.7e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EPE30511.1 - 2.7e-08 33.0 0.0 7e-08 31.6 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EPE30511.1 - 6.8e-06 25.5 0.0 1.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EPE30511.1 - 3.5e-05 22.8 0.1 0.00099 18.1 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EPE30511.1 - 0.0049 16.7 0.2 0.012 15.5 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE30511.1 - 0.02 14.5 0.0 0.057 13.0 0.0 1.8 2 0 0 2 2 2 0 KR domain 3Beta_HSD PF01073.14 EPE30511.1 - 0.041 12.5 0.0 0.085 11.5 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aldose_epim PF01263.15 EPE30512.1 - 2.5e-48 164.7 0.1 3.3e-48 164.3 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ATP-synt_ab PF00006.20 EPE30513.1 - 1.2e-60 204.6 0.0 1.6e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPE30513.1 - 1.4e-14 54.4 0.0 2.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPE30513.1 - 2.1e-12 47.0 0.7 4.4e-12 46.0 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EPE30513.1 - 0.00034 20.4 0.2 0.00074 19.3 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain Asp PF00026.18 EPE30514.1 - 3.6e-37 128.2 0.1 3.6e-37 128.2 0.1 2.8 2 1 0 2 2 2 1 Eukaryotic aspartyl protease HET PF06985.6 EPE30515.1 - 3e-07 30.6 0.0 5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peroxidase_2 PF01328.12 EPE30517.1 - 5e-13 48.4 0.8 4.2e-12 45.3 0.6 2.1 1 1 0 1 1 1 1 Peroxidase, family 2 DUF4402 PF14352.1 EPE30518.1 - 0.65 10.4 3.3 0.77 10.2 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4402) PBP PF01161.15 EPE30519.1 - 2.4e-09 37.1 0.1 3.6e-09 36.6 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_transf_28 PF03033.15 EPE30522.1 - 4.2e-18 65.4 0.0 1.2e-17 63.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EPE30522.1 - 6.9e-07 28.1 0.1 1.1e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EPE30522.1 - 0.017 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF2985 PF11204.3 EPE30523.1 - 2.3e-39 133.0 0.7 2.3e-39 133.0 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF4349 PF14257.1 EPE30523.1 - 0.42 9.7 1.2 0.94 8.6 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) SPX PF03105.14 EPE30524.1 - 8.2e-45 153.7 3.0 1.5e-44 152.8 2.1 1.4 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EPE30524.1 - 1.5e-32 113.0 43.4 2.2e-32 112.5 30.1 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EPE30524.1 - 1.3e-15 56.9 24.4 1.3e-15 56.9 16.9 2.4 1 1 1 2 2 2 2 Citrate transporter APH PF01636.18 EPE30525.1 - 1.8e-18 67.1 0.0 2.7e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE30525.1 - 3.5e-07 30.0 0.0 6.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPE30525.1 - 0.00021 20.5 0.0 0.00039 19.6 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EPE30525.1 - 0.031 12.9 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) p450 PF00067.17 EPE30527.1 - 5e-50 170.3 0.0 6.7e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EPE30528.1 - 4.4e-07 28.7 1.0 6.7e-06 24.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Aminotran_3 PF00202.16 EPE30529.1 - 4.5e-97 324.9 0.0 5.6e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EPE30529.1 - 0.0058 15.6 0.0 0.0091 14.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Bestrophin PF01062.16 EPE30530.1 - 1.1e-48 165.7 0.5 8.3e-47 159.5 0.4 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Abhydrolase_3 PF07859.8 EPE30531.1 - 2.8e-36 125.1 0.0 1.7e-25 89.8 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EPE30531.1 - 0.013 14.1 0.0 0.023 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) CPSF100_C PF13299.1 EPE30532.1 - 0.13 12.4 0.1 0.18 11.9 0.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Glyco_hydro_62 PF03664.8 EPE30533.1 - 7.7e-138 458.1 11.2 8.9e-138 457.8 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Abhydrolase_5 PF12695.2 EPE30534.1 - 8.4e-06 25.6 0.0 3.9e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE30534.1 - 0.0034 16.8 0.1 0.0082 15.6 0.0 1.7 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EPE30534.1 - 0.13 11.8 0.0 6.1 6.4 0.0 2.2 1 1 1 2 2 2 0 Lipase (class 3) DUF1674 PF07896.7 EPE30538.1 - 2.1e-17 63.0 5.4 5.5e-17 61.7 3.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) Trp_syntA PF00290.15 EPE30539.1 - 1e-93 312.6 0.1 2.9e-93 311.1 0.0 1.7 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 EPE30539.1 - 5.6e-49 167.0 0.7 9.9e-49 166.2 0.5 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rxt3 PF08642.5 EPE30540.1 - 1.8e-25 89.3 0.2 6.2e-25 87.6 0.0 2.0 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EPE30540.1 - 0.00037 20.4 0.0 0.0098 15.8 0.0 2.5 2 0 0 2 2 2 1 LCCL domain DUF1777 PF08648.7 EPE30540.1 - 1.5 8.5 50.7 0.13 11.9 24.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Aminotran_3 PF00202.16 EPE30541.1 - 1.8e-86 290.0 0.5 2.1e-86 289.8 0.4 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ZapA PF05164.8 EPE30541.1 - 0.15 12.0 0.1 0.48 10.4 0.1 1.9 1 0 0 1 1 1 0 Cell division protein ZapA DUF829 PF05705.9 EPE30542.1 - 1.4e-39 136.2 0.0 1.7e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) CLN3 PF02487.12 EPE30544.1 - 1.6e-99 333.4 23.7 3.7e-97 325.6 16.4 2.9 1 1 0 1 1 1 1 CLN3 protein AA_permease_2 PF13520.1 EPE30545.1 - 1.7e-59 201.5 41.1 1.6e-57 194.9 28.5 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE30545.1 - 2e-15 56.1 23.5 2e-15 56.1 16.3 2.1 1 1 1 2 2 2 2 Amino acid permease DUF3092 PF11289.3 EPE30545.1 - 0.043 13.0 1.1 0.088 12.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) PPTA PF01239.17 EPE30547.1 - 2.3e-23 80.4 12.3 7.5e-06 25.0 1.2 6.2 5 1 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Sporozoite_P67 PF05642.6 EPE30547.1 - 0.077 10.8 0.7 0.097 10.5 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.27 EPE30548.1 - 2.4e-09 36.7 6.3 0.00014 21.5 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EPE30548.1 - 0.19 10.5 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region His_Phos_2 PF00328.17 EPE30549.1 - 0.00011 21.6 0.0 0.023 14.0 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) YwqJ-deaminase PF14431.1 EPE30551.1 - 0.2 11.5 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 YwqJ-like deaminase F-box-like PF12937.2 EPE30552.1 - 0.00061 19.4 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like Dynactin PF12455.3 EPE30553.1 - 7.3e-95 316.9 2.6 7.3e-95 316.9 1.8 2.5 3 0 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 EPE30553.1 - 3.5e-21 74.6 0.1 6.4e-21 73.8 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain DUF2158 PF09926.4 EPE30553.1 - 0.095 12.1 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) Ribosomal_S6e PF01092.14 EPE30555.1 - 1.3e-62 209.0 0.3 2.4e-62 208.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Ctf8 PF09696.5 EPE30556.1 - 1.6e-32 111.8 0.0 2e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Ctf8 DUF1128 PF06569.6 EPE30556.1 - 0.05 13.3 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) Cupin_2 PF07883.6 EPE30557.1 - 0.0007 19.0 0.1 0.002 17.6 0.0 1.7 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EPE30557.1 - 0.00083 18.8 0.0 0.0016 17.9 0.0 1.5 1 1 0 1 1 1 1 Cupin GPI PF06560.6 EPE30557.1 - 0.0052 15.8 0.0 0.0064 15.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Ank_2 PF12796.2 EPE30559.1 - 6.1e-08 32.9 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE30559.1 - 1.1e-06 28.1 0.0 2.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EPE30559.1 - 4.6e-06 27.0 0.0 1.3e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE30559.1 - 5.7e-06 26.0 0.0 4e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EPE30559.1 - 1.3e-05 25.2 0.0 3.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) COG2 PF06148.6 EPE30559.1 - 0.078 12.8 1.7 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SbcD_C PF12320.3 EPE30559.1 - 0.25 11.4 1.9 0.56 10.2 1.3 1.6 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Reo_sigmaC PF04582.7 EPE30559.1 - 1.1 8.3 11.6 0.16 11.1 1.0 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fungal_trans PF04082.13 EPE30560.1 - 1.4e-10 40.4 0.1 7.1e-10 38.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE30560.1 - 9.9e-09 34.9 12.4 2.4e-08 33.7 8.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE30561.1 - 9.2e-41 139.7 47.7 1.4e-39 135.8 32.3 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily NPP1 PF05630.6 EPE30562.1 - 1e-54 185.4 0.0 1.2e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Tropomodulin PF03250.9 EPE30563.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Tropomodulin Phosphoesterase PF04185.9 EPE30565.1 - 5.5e-30 104.8 0.5 9e-30 104.1 0.4 1.3 1 0 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.18 EPE30565.1 - 0.0058 15.8 0.2 0.009 15.2 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Pribosyltran_N PF13793.1 EPE30566.1 - 3.4e-43 146.0 0.4 2e-42 143.5 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EPE30566.1 - 2.1e-40 138.4 2.2 8.2e-33 113.6 1.1 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EPE30566.1 - 2.4e-12 46.6 0.6 1.2e-11 44.4 0.2 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPE30566.1 - 0.0031 16.7 0.2 0.0052 16.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF913 PF06025.7 EPE30567.1 - 8.8e-124 413.0 0.0 8.8e-124 413.0 0.0 3.9 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EPE30567.1 - 2.2e-98 329.3 0.0 4.4e-98 328.3 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EPE30567.1 - 7.2e-81 272.0 1.1 7.2e-81 272.0 0.7 2.5 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EPE30567.1 - 1.1e-30 105.7 8.7 1.1e-30 105.7 6.0 4.4 3 1 1 4 4 4 1 Domain of unknown function (DUF4414) UBA PF00627.26 EPE30567.1 - 4.8e-05 23.0 0.1 0.0002 21.1 0.0 2.2 1 0 0 1 1 1 1 UBA/TS-N domain RabGAP-TBC PF00566.13 EPE30568.1 - 1.1e-48 165.5 3.0 5.5e-48 163.2 0.0 2.8 3 1 0 3 3 3 1 Rab-GTPase-TBC domain PilJ PF13675.1 EPE30568.1 - 0.025 14.9 11.6 0.059 13.6 0.6 3.2 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term ApoO PF09769.4 EPE30568.1 - 0.24 11.1 4.6 0.5 10.0 2.7 2.0 1 1 0 1 1 1 0 Apolipoprotein O Microtub_assoc PF07989.6 EPE30568.1 - 0.28 11.0 18.6 0.1 12.4 5.3 2.8 2 0 0 2 2 2 0 Microtubule associated HALZ PF02183.13 EPE30568.1 - 2.5 7.9 20.8 0.39 10.4 0.5 4.1 3 1 1 4 4 4 0 Homeobox associated leucine zipper MFS_1 PF07690.11 EPE30569.1 - 2.8e-24 85.4 34.4 2.8e-24 85.4 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4334 PF14232.1 EPE30571.1 - 0.055 13.1 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) GCN5L1 PF06320.8 EPE30573.1 - 3.4e-09 36.5 0.1 5.5e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Striatin PF08232.7 EPE30573.1 - 0.046 14.0 7.0 0.052 13.8 0.9 2.4 1 1 1 2 2 2 0 Striatin family GAS PF13851.1 EPE30573.1 - 0.1 11.7 0.2 0.31 10.2 0.1 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Ribosomal_S8e PF01201.17 EPE30574.1 - 1e-45 155.0 1.1 1.2e-45 154.8 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EPE30574.1 - 0.031 14.5 3.4 0.033 14.4 1.2 1.9 2 1 0 2 2 2 0 Small acidic protein family Methyltransf_2 PF00891.13 EPE30575.1 - 3.5e-30 104.9 0.0 4.7e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EPE30575.1 - 0.0022 18.5 0.0 0.005 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE30576.1 - 8.6e-19 67.8 0.0 1.7e-18 66.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE30576.1 - 5.9e-10 39.5 0.0 1.5e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE30576.1 - 1.4e-09 37.6 0.0 2.9e-08 33.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE30576.1 - 2e-08 34.6 0.0 3.5e-07 30.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE30576.1 - 8e-07 29.6 0.0 2.3e-05 24.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPE30576.1 - 0.0017 17.4 0.0 0.0079 15.2 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EPE30576.1 - 0.003 16.7 0.0 0.073 12.1 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPE30576.1 - 0.013 15.8 0.0 0.12 12.7 0.0 2.6 3 1 0 3 3 3 0 Methyltransferase domain FtsJ PF01728.14 EPE30576.1 - 0.014 15.3 0.1 0.071 13.1 0.0 1.9 1 1 0 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.8 EPE30576.1 - 0.021 13.9 0.2 0.081 12.0 0.0 1.9 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EPE30576.1 - 0.026 13.7 0.0 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_9 PF08003.6 EPE30576.1 - 0.076 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.9 EPE30576.1 - 0.08 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 EPE30576.1 - 0.12 11.4 0.0 0.3 10.1 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase HTH_20 PF12840.2 EPE30576.1 - 0.16 11.8 0.0 0.55 10.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3410 PF11890.3 EPE30578.1 - 0.13 11.8 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) Aldo_ket_red PF00248.16 EPE30579.1 - 3.7e-56 190.0 0.0 4.1e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 EPE30579.1 - 0.0075 16.5 0.1 0.089 13.0 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase LmjF365940-deam PF14421.1 EPE30580.1 - 2.7 7.3 6.7 20 4.4 0.1 3.3 2 1 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases His_Phos_1 PF00300.17 EPE30581.1 - 2.2e-18 66.8 0.0 3.3e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WD40 PF00400.27 EPE30582.1 - 1.5e-69 227.6 21.7 9.7e-13 47.4 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EPE30582.1 - 3e-10 38.8 0.4 0.00026 19.2 0.0 4.6 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPE30582.1 - 2.5e-06 26.5 0.1 0.28 9.8 0.0 3.2 2 1 0 2 2 2 2 Nup133 N terminal like bZIP_1 PF00170.16 EPE30582.1 - 0.0024 17.7 0.5 0.0044 16.9 0.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor tRNA-synt_1 PF00133.17 EPE30583.1 - 1.9e-35 121.9 0.0 1.2e-23 82.9 0.0 4.2 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EPE30583.1 - 2.2e-18 66.1 0.2 2e-11 43.2 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EPE30583.1 - 1.1e-11 44.7 0.6 1.1e-11 44.7 0.4 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EPE30583.1 - 8.1e-08 31.7 0.0 2.2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Clat_adaptor_s PF01217.15 EPE30584.1 - 6.1e-44 149.1 0.0 1.2e-43 148.2 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.11 EPE30585.1 - 3e-33 113.8 0.0 4.1e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain zf-CSL PF05207.8 EPE30586.1 - 3e-24 84.2 0.4 3.7e-24 83.9 0.3 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EPE30586.1 - 0.023 14.6 0.2 0.041 13.8 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Prok-RING_1 PF14446.1 EPE30586.1 - 1.1 8.9 3.9 2.9 7.6 2.7 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_clus PF00172.13 EPE30587.1 - 3.2e-07 30.1 6.1 5.9e-07 29.2 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE30587.1 - 7.6e-05 21.4 0.0 0.00018 20.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain FGGY_C PF02782.11 EPE30589.1 - 9.4e-76 253.8 3.5 1.1e-75 253.6 0.9 2.1 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EPE30589.1 - 1.6e-67 227.3 0.0 2.1e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 EPE30590.1 - 1.3e-53 181.8 7.9 1.5e-53 181.6 5.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein ABC_membrane_2 PF06472.10 EPE30591.1 - 1.9e-106 355.2 1.5 2.9e-106 354.7 1.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EPE30591.1 - 1.3e-18 67.6 0.0 2.9e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPE30591.1 - 0.0005 20.1 0.2 0.0021 18.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPE30591.1 - 0.016 15.2 0.3 0.044 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EPE30591.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EPE30591.1 - 0.017 15.4 0.4 0.056 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EPE30591.1 - 0.03 13.5 0.1 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EPE30591.1 - 0.18 10.9 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MFS_1 PF07690.11 EPE30593.1 - 7.6e-24 84.0 19.3 7.6e-24 84.0 13.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Connexin PF00029.14 EPE30594.1 - 0.0056 16.7 0.2 0.0081 16.2 0.1 1.2 1 0 0 1 1 1 1 Connexin Vma12 PF11712.3 EPE30594.1 - 0.033 13.8 0.1 0.042 13.5 0.1 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1118 PF06549.7 EPE30594.1 - 0.046 13.8 0.5 0.071 13.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) EphA2_TM PF14575.1 EPE30594.1 - 0.083 13.2 0.7 1.4 9.3 0.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3995 PF13160.1 EPE30594.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) MMgT PF10270.4 EPE30594.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Membrane magnesium transporter DUF843 PF05814.6 EPE30594.1 - 0.21 11.4 1.5 0.4 10.5 0.0 1.9 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF843) adh_short PF00106.20 EPE30595.1 - 8.3e-12 45.3 0.0 1.5e-11 44.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE30595.1 - 8.5e-05 22.4 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE30595.1 - 0.0064 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 KR domain PS_Dcarbxylase PF02666.10 EPE30596.1 - 5.9e-48 162.8 0.0 7.8e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M35 PF02102.10 EPE30598.1 - 1.7e-103 346.0 26.8 2e-103 345.7 18.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EPE30598.1 - 3.9e-06 27.4 1.7 6.7e-06 26.6 1.2 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Pkinase PF00069.20 EPE30600.1 - 3.1e-37 128.1 0.0 4.2e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30600.1 - 1.1e-20 73.8 0.0 1.5e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPE30600.1 - 0.00043 20.0 0.1 0.00083 19.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.11 EPE30601.1 - 8.8e-20 70.7 36.7 1.4e-13 50.3 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE30601.1 - 7.2e-13 47.9 22.4 1.3e-12 47.0 14.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Fasciclin PF02469.17 EPE30602.1 - 1e-45 154.8 1.4 1e-24 86.9 0.0 2.4 2 1 0 2 2 2 2 Fasciclin domain MFS_1 PF07690.11 EPE30603.1 - 1.7e-18 66.4 36.4 1.6e-09 36.9 6.9 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EPE30604.1 - 1.2e-60 205.3 0.1 1.6e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 EPE30605.1 - 4.4e-33 114.3 0.1 8.8e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2470 PF10615.4 EPE30606.1 - 6.4e-17 61.5 0.0 9.7e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) 6PF2K PF01591.13 EPE30607.1 - 8e-80 267.0 0.1 1.1e-79 266.6 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPE30607.1 - 5.9e-34 117.4 0.1 1.5e-33 116.1 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EPE30607.1 - 1.6e-06 28.0 0.0 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPE30607.1 - 0.00039 19.7 0.0 0.0028 16.8 0.0 1.8 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EPE30607.1 - 0.00048 20.9 0.2 0.028 15.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPE30607.1 - 0.019 14.0 0.1 0.33 10.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.15 EPE30607.1 - 0.096 12.3 0.0 0.27 10.8 0.0 1.8 1 1 0 1 1 1 0 Adenylylsulphate kinase DUF3328 PF11807.3 EPE30609.1 - 0.55 9.8 7.0 2.1 7.9 4.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EPE30610.1 - 1.3e-56 191.7 2.4 1.7e-56 191.2 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Syd PF07348.7 EPE30610.1 - 0.81 9.0 3.4 0.46 9.8 0.3 2.0 3 0 0 3 3 3 0 Syd protein (SUKH-2) Herpes_UL73 PF03554.8 EPE30610.1 - 2.5 8.0 6.1 0.95 9.3 2.2 1.8 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein DUF3328 PF11807.3 EPE30611.1 - 1.3e-26 93.6 0.2 1.9e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EPE30612.1 - 2e-50 171.4 0.4 2.7e-50 171.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Sigma70_r3 PF04539.11 EPE30613.1 - 0.024 14.5 6.6 12 5.9 0.1 3.2 3 0 0 3 3 3 0 Sigma-70 region 3 SRP19 PF01922.12 EPE30613.1 - 0.031 14.8 2.9 33 5.1 0.1 3.1 1 1 2 3 3 3 0 SRP19 protein Rotamase_3 PF13616.1 EPE30613.1 - 0.17 12.1 1.3 21 5.4 0.0 2.9 1 1 2 3 3 3 0 PPIC-type PPIASE domain DUF1442 PF07279.6 EPE30613.1 - 0.18 10.8 1.9 7.2 5.6 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1442) RTC_insert PF05189.8 EPE30613.1 - 0.26 11.3 3.6 12 5.9 0.0 2.9 3 0 0 3 3 3 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF3054 PF11255.3 EPE30613.1 - 4.7 7.0 5.4 2.5 7.9 0.4 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3054) DUF3328 PF11807.3 EPE30614.1 - 7.3e-27 94.4 0.4 1e-26 94.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EPE30615.1 - 7.2e-25 87.9 2.7 9.1e-25 87.6 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) CD20 PF04103.10 EPE30615.1 - 0.052 13.4 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 CD20-like family DUF3328 PF11807.3 EPE30616.1 - 8.4e-26 90.9 2.9 8.9e-25 87.6 2.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) TMEM191C PF15194.1 EPE30616.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 TMEM191C family Ank_2 PF12796.2 EPE30617.1 - 5.5e-33 113.1 0.9 2.5e-19 69.4 0.1 2.6 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE30617.1 - 4.3e-25 86.2 2.3 4.1e-08 32.6 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EPE30617.1 - 5.6e-18 64.5 0.1 5.1e-06 26.5 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE30617.1 - 3.5e-17 60.7 1.2 6.5e-06 25.8 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EPE30617.1 - 8.1e-16 58.0 0.1 1.1e-11 44.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) bZIP_1 PF00170.16 EPE30617.1 - 0.0073 16.2 6.9 0.019 14.8 4.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF2161 PF09929.4 EPE30617.1 - 0.19 11.6 0.6 0.42 10.5 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) TPR_12 PF13424.1 EPE30618.1 - 0.03 14.2 0.2 0.33 10.9 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.11 EPE30619.1 - 1.5e-20 73.2 13.4 2e-20 72.8 9.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1218 PF06749.7 EPE30619.1 - 0.26 11.7 2.8 0.98 9.9 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Sulfatase PF00884.18 EPE30620.1 - 5.3e-47 160.5 1.0 6.3e-26 91.2 0.0 2.4 2 1 1 3 3 3 2 Sulfatase Phosphodiest PF01663.17 EPE30620.1 - 1.6e-05 24.4 0.7 0.00018 20.9 0.5 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Thioredox_DsbH PF03190.10 EPE30620.1 - 0.0018 18.0 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 DUF229 PF02995.12 EPE30620.1 - 0.037 12.4 0.0 0.048 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) NUDIX PF00293.23 EPE30621.1 - 5.7e-05 22.7 0.0 9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HET PF06985.6 EPE30622.1 - 5.2e-21 75.2 0.4 1.2e-20 74.0 0.3 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Integrase_DNA PF02920.10 EPE30622.1 - 0.1 12.0 0.0 0.42 10.0 0.0 2.0 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase ADH_N PF08240.7 EPE30623.1 - 2.8e-18 65.6 3.1 2.8e-18 65.6 2.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE30623.1 - 6.3e-15 54.8 0.0 1.5e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPE30623.1 - 3e-05 23.2 0.0 6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EPE30623.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EPE30623.1 - 0.052 13.4 0.1 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EPE30623.1 - 0.069 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 EPE30623.1 - 0.099 12.4 0.5 0.19 11.5 0.3 1.4 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.15 EPE30623.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans_2 PF11951.3 EPE30624.1 - 0.078 11.5 0.1 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_transf_8 PF01501.15 EPE30625.1 - 3.5e-15 56.0 0.0 5.4e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 PsaD PF02531.11 EPE30625.1 - 0.015 14.5 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 PsaD Mannosyl_trans3 PF11051.3 EPE30625.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative FAD_binding_3 PF01494.14 EPE30626.1 - 3.2e-84 282.9 0.0 4.4e-84 282.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EPE30626.1 - 5.5e-05 23.1 0.1 0.00018 21.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE30626.1 - 0.00063 18.9 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EPE30626.1 - 0.0018 17.2 0.0 0.012 14.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE30626.1 - 0.004 17.1 0.8 0.01 15.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE30626.1 - 0.0065 15.3 0.1 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EPE30626.1 - 0.041 12.8 0.1 0.068 12.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EPE30626.1 - 0.071 11.9 0.4 0.1 11.4 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Mqo PF06039.10 EPE30626.1 - 0.11 10.6 0.0 0.35 8.9 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.22 EPE30626.1 - 0.16 12.4 0.0 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EPE30626.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyoxalase PF00903.20 EPE30627.1 - 9.3e-11 41.8 3.6 8.4e-09 35.4 1.4 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EPE30627.1 - 0.0012 19.4 0.6 1.8 9.1 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EPE30627.1 - 0.0089 16.0 0.1 1.6 8.8 0.0 2.9 3 1 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily F-box-like PF12937.2 EPE30628.1 - 0.0052 16.4 0.1 0.029 14.0 0.1 2.3 1 1 0 1 1 1 1 F-box-like Bromodomain PF00439.20 EPE30629.1 - 1.9e-13 50.1 0.0 4.5e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain ATG16 PF08614.6 EPE30630.1 - 0.03 14.1 0.3 0.044 13.5 0.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SlyX PF04102.7 EPE30630.1 - 3.1 8.2 8.4 29 5.1 5.8 2.3 1 1 0 1 1 1 0 SlyX Steroid_dh PF02544.11 EPE30631.1 - 3.9e-30 104.6 0.8 5.9e-30 104.0 0.6 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EPE30631.1 - 0.00017 21.6 0.5 0.00034 20.6 0.0 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EPE30631.1 - 0.0016 17.7 0.5 0.0037 16.5 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) DUF1418 PF07214.7 EPE30631.1 - 0.023 14.2 0.1 0.054 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) DOCK-C2 PF14429.1 EPE30632.1 - 6.9e-27 94.2 0.0 1.2e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.23 EPE30632.1 - 2.3e-05 23.6 0.0 4.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPE30632.1 - 0.00044 19.7 0.0 0.0038 16.7 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain Ded_cyto PF06920.8 EPE30633.1 - 1.3e-11 44.0 0.3 7.4e-11 41.6 0.2 2.2 1 1 0 1 1 1 1 Dedicator of cytokinesis MFS_1 PF07690.11 EPE30634.1 - 7.1e-38 130.2 46.2 8.2e-37 126.7 33.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily 4HBT_2 PF13279.1 EPE30635.1 - 1.6e-09 38.2 0.0 2.6e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily TMEM191C PF15194.1 EPE30635.1 - 0.1 12.4 0.8 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 TMEM191C family DUF605 PF04652.11 EPE30636.1 - 3.6 6.8 21.1 5.2 6.3 14.6 1.2 1 0 0 1 1 1 0 Vta1 like GrpE PF01025.14 EPE30637.1 - 3.6e-47 159.9 6.3 5.2e-47 159.4 4.3 1.2 1 0 0 1 1 1 1 GrpE DUF2763 PF10961.3 EPE30640.1 - 1.2 9.6 5.7 0.23 11.9 0.9 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2763) Reprolysin_5 PF13688.1 EPE30641.1 - 2e-60 204.0 8.8 2e-60 204.0 6.1 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EPE30641.1 - 2.7e-48 164.3 2.8 9e-48 162.6 1.9 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EPE30641.1 - 1.4e-47 161.9 2.4 3.6e-47 160.5 1.7 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EPE30641.1 - 4.2e-19 69.2 0.6 4.2e-19 69.2 0.4 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EPE30641.1 - 1.6e-15 57.0 30.8 1.6e-15 57.0 21.3 5.0 3 2 2 5 5 5 1 Disintegrin Reprolysin PF01421.14 EPE30641.1 - 0.0048 16.5 10.7 0.0048 16.5 7.4 3.2 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 EPE30641.1 - 0.0056 16.4 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide GP41 PF00517.12 EPE30641.1 - 0.07 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral envelope protein AMP-binding PF00501.23 EPE30642.1 - 3.3e-91 305.7 0.3 4e-91 305.4 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE30642.1 - 2.3e-23 82.9 0.7 1.3e-20 74.0 0.3 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain DUF1967 PF09269.6 EPE30642.1 - 0.12 12.0 0.0 0.56 9.9 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Aspzincin_M35 PF14521.1 EPE30643.1 - 0.009 16.5 2.0 0.067 13.7 1.4 2.3 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF695 PF05117.7 EPE30643.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF695) Peptidase_M35 PF02102.10 EPE30643.1 - 0.11 11.1 5.2 0.35 9.4 0.9 2.1 2 0 0 2 2 2 0 Deuterolysin metalloprotease (M35) family tRNA-synt_2d PF01409.15 EPE30645.1 - 4.5e-47 160.3 0.3 9.2e-26 90.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EPE30645.1 - 1.1e-25 89.5 0.0 2.5e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.22 EPE30646.1 - 5.5e-60 199.0 0.1 5.1e-20 70.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_A_bac PF01000.21 EPE30647.1 - 2.5e-32 111.3 0.0 3.9e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EPE30647.1 - 3.8e-16 57.9 0.0 4.9e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Calcipressin PF04847.7 EPE30648.1 - 5.8e-46 156.3 0.1 7.9e-46 155.9 0.1 1.1 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 EPE30648.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 DUF2236 PF09995.4 EPE30649.1 - 1.1e-36 126.3 1.4 1.6e-36 125.8 1.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) WD40 PF00400.27 EPE30650.1 - 1.5e-27 94.4 1.4 3.2e-06 26.8 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat PD40 PF07676.7 EPE30650.1 - 0.072 12.7 0.2 4.9 6.9 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Neugrin PF06413.6 EPE30651.1 - 3.1e-13 50.0 0.3 3.1e-13 50.0 0.2 1.7 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 EPE30651.1 - 1.2e-06 28.6 0.3 3.7e-06 26.9 0.2 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Fil_haemagg_2 PF13332.1 EPE30651.1 - 4.4 7.0 6.0 2 8.1 0.9 2.1 2 0 0 2 2 2 0 Haemagluttinin repeat DUF1180 PF06679.7 EPE30652.1 - 1.2 9.0 5.7 0.28 11.0 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TRAP-delta PF05404.7 EPE30653.1 - 0.049 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) DUF1590 PF07629.6 EPE30653.1 - 0.11 12.0 0.4 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) OTT_1508_deam PF14441.1 EPE30654.1 - 1.9e-09 37.4 0.0 4.1e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 OTT_1508-like deaminase HTH_41 PF14502.1 EPE30654.1 - 0.018 14.6 0.3 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MaoC_dehydratas PF01575.14 EPE30655.1 - 6.9e-17 60.9 0.0 1.1e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EPE30655.1 - 0.012 15.4 0.0 0.3 10.8 0.0 2.9 2 2 0 2 2 2 0 N-terminal half of MaoC dehydratase 4HBT PF03061.17 EPE30655.1 - 0.019 15.1 0.1 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Acetyltransf_8 PF13523.1 EPE30656.1 - 9.9e-45 152.1 0.4 1.6e-44 151.4 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPE30656.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 EPE30657.1 - 1e-93 314.0 0.0 1.2e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE30657.1 - 4.5e-10 40.3 0.0 1.1e-09 39.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain K_oxygenase PF13434.1 EPE30658.1 - 1.1e-41 142.8 0.0 1.4e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPE30658.1 - 7.6e-06 25.7 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding Mqo PF06039.10 EPE30658.1 - 0.0027 15.9 0.0 0.025 12.7 0.0 2.0 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) ABC_membrane PF00664.18 EPE30659.1 - 2.2e-76 256.8 25.9 1.4e-41 142.7 4.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPE30659.1 - 3e-61 205.6 0.0 7.3e-30 104.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPE30659.1 - 5.6e-13 48.6 0.5 0.0049 16.1 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE30659.1 - 6.8e-10 39.3 0.1 0.026 14.5 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EPE30659.1 - 1e-08 34.5 0.8 0.0049 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EPE30659.1 - 5.9e-08 33.5 0.0 0.0029 18.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPE30659.1 - 1.3e-07 31.7 5.5 0.0017 18.3 0.9 3.0 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 EPE30659.1 - 2.1e-05 24.6 0.3 1.9 8.6 0.1 4.3 4 1 0 4 4 3 2 AAA domain DUF258 PF03193.11 EPE30659.1 - 3.2e-05 23.1 0.1 0.03 13.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 EPE30659.1 - 6.6e-05 22.8 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EPE30659.1 - 0.00018 20.2 0.3 0.0038 15.8 0.0 2.8 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_30 PF13604.1 EPE30659.1 - 0.00023 20.7 0.2 1.2 8.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EPE30659.1 - 0.00054 19.8 0.6 1.9 8.4 0.1 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EPE30659.1 - 0.00062 20.0 0.0 0.31 11.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EPE30659.1 - 0.00066 19.1 0.3 2.2 7.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EPE30659.1 - 0.00088 18.4 0.1 0.45 9.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin APS_kinase PF01583.15 EPE30659.1 - 0.00094 18.8 0.1 0.12 12.0 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA PF00004.24 EPE30659.1 - 0.0014 18.8 0.1 12 6.0 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EPE30659.1 - 0.0032 17.8 0.1 0.24 11.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPE30659.1 - 0.0082 15.8 0.0 6.6 6.4 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EPE30659.1 - 0.017 14.9 0.1 0.68 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 EPE30659.1 - 0.05 13.3 0.1 9.9 5.8 0.0 2.9 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EPE30659.1 - 0.052 12.9 0.1 14 4.9 0.0 2.8 2 0 0 2 2 2 0 AAA-like domain Mito_fiss_Elm1 PF06258.6 EPE30659.1 - 0.16 10.8 1.3 13 4.6 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial fission ELM1 MMR_HSR1 PF01926.18 EPE30659.1 - 0.16 11.9 0.1 21 5.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DPBB_1 PF03330.13 EPE30660.1 - 5.4e-07 29.5 2.2 1.2e-06 28.4 0.1 2.0 1 1 1 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel zinc_ribbon_2 PF13240.1 EPE30660.1 - 0.074 12.5 1.8 17 5.0 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EPE30660.1 - 9 5.6 7.7 77 2.6 0.0 3.3 3 1 0 3 3 3 0 zinc-ribbon domain Isochorismatase PF00857.15 EPE30661.1 - 5.9e-25 88.1 0.0 3.4e-23 82.4 0.0 2.3 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 EPE30661.1 - 6.1e-23 81.6 0.0 1e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_3 PF14497.1 EPE30661.1 - 4.8e-07 30.1 0.0 1.4e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPE30661.1 - 0.021 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 2OG-FeII_Oxy PF03171.15 EPE30661.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily GST_C PF00043.20 EPE30661.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ECH PF00378.15 EPE30662.1 - 1.8e-40 138.6 0.1 1.4e-39 135.7 0.1 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EPE30662.1 - 0.004 17.2 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region TAF8_C PF10406.4 EPE30663.1 - 4.2e-18 65.1 0.9 1.7e-17 63.2 0.6 2.1 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EPE30663.1 - 1e-07 31.5 0.0 2.3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated SKN1 PF03935.10 EPE30666.1 - 3.7e-222 737.9 0.7 4.4e-222 737.6 0.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF1751 PF08551.5 EPE30667.1 - 9.2e-26 90.0 4.2 1.9e-25 89.0 2.9 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) WD40 PF00400.27 EPE30668.1 - 3e-19 68.0 7.4 7e-05 22.5 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat LisH PF08513.6 EPE30668.1 - 7.2e-05 22.4 0.3 0.082 12.6 0.1 2.8 3 0 0 3 3 3 2 LisH Nucleoporin_N PF08801.6 EPE30668.1 - 0.048 12.4 0.0 0.46 9.1 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like TPR_1 PF00515.23 EPE30669.1 - 5.7e-53 174.4 27.4 4.6e-08 32.3 0.0 10.6 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 EPE30669.1 - 4e-48 160.9 33.8 1.9e-13 49.8 1.6 6.4 2 2 4 7 7 7 7 TPR repeat TPR_2 PF07719.12 EPE30669.1 - 5e-48 157.1 21.7 1.7e-05 24.3 0.0 10.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.1 EPE30669.1 - 4.1e-41 135.6 14.3 8.5e-06 25.1 0.6 10.3 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 EPE30669.1 - 4.9e-34 116.2 6.2 4e-07 30.5 0.0 6.6 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EPE30669.1 - 1.3e-30 105.1 23.0 1.3e-06 28.2 0.1 7.3 3 2 5 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 EPE30669.1 - 6.5e-28 94.5 17.8 0.0013 18.7 0.1 10.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 EPE30669.1 - 3.7e-25 86.1 7.1 0.018 15.6 0.1 9.5 3 2 7 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.1 EPE30669.1 - 1.2e-23 80.9 16.2 0.0017 18.0 0.0 9.8 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 EPE30669.1 - 1.4e-22 78.5 15.4 0.0088 16.4 0.0 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPE30669.1 - 2.3e-20 72.6 18.7 9e-06 25.9 0.1 6.6 5 1 2 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EPE30669.1 - 4e-15 55.7 9.9 1.1e-07 31.8 1.3 4.1 3 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EPE30669.1 - 7.6e-13 48.1 10.9 0.0013 18.5 1.0 7.0 1 1 7 8 8 8 4 Tetratricopeptide repeat TPR_15 PF13429.1 EPE30669.1 - 3.7e-10 39.3 7.2 0.012 14.6 0.0 4.9 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_21 PF09976.4 EPE30669.1 - 2.7e-05 24.1 12.1 0.2 11.6 1.5 4.2 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 EPE30669.1 - 0.0001 22.3 1.5 0.8 9.8 0.0 4.5 5 1 1 6 6 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 EPE30669.1 - 0.0023 17.4 3.0 0.43 10.0 0.0 3.5 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.1 EPE30669.1 - 0.084 12.0 13.3 15 4.6 0.4 4.7 1 1 4 5 5 5 0 Soluble NSF attachment protein, SNAP GAS PF13851.1 EPE30669.1 - 0.11 11.6 1.3 0.2 10.8 0.1 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_10 PF13374.1 EPE30669.1 - 0.84 9.6 18.6 20 5.2 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Ribosomal_L3 PF00297.17 EPE30670.1 - 1.8e-117 391.4 7.7 2.1e-117 391.1 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 NuiA PF07924.6 EPE30671.1 - 0.017 14.9 0.6 1.2 9.1 0.1 2.3 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein APC_CDC26 PF10471.4 EPE30671.1 - 0.11 13.2 3.6 0.33 11.7 2.5 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF1296 PF06972.6 EPE30671.1 - 1.5 8.8 5.6 11 6.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) Alpha-L-AF_C PF06964.7 EPE30672.1 - 8.5e-35 120.1 0.0 1.4e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 EPE30673.1 - 1.2e-101 340.5 21.6 1.4e-101 340.3 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE30673.1 - 8e-27 93.8 26.5 1.1e-20 73.6 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Med25 PF11232.3 EPE30673.1 - 0.015 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 EMP70 PF02990.11 EPE30673.1 - 0.023 13.1 2.7 0.039 12.4 1.8 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 Lig_chan PF00060.21 EPE30673.1 - 0.47 10.1 2.3 12 5.6 0.1 2.6 2 1 0 2 2 2 0 Ligand-gated ion channel APH PF01636.18 EPE30674.1 - 1.2e-09 38.2 0.0 4.1e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EPE30674.1 - 0.0001 21.0 0.0 0.036 12.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) RIO1 PF01163.17 EPE30674.1 - 0.019 14.3 0.1 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.9 EPE30674.1 - 0.073 12.0 0.0 7.2 5.4 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase DUF4574 PF15141.1 EPE30674.1 - 0.17 11.6 0.8 0.34 10.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) Sugar_tr PF00083.19 EPE30675.1 - 5.3e-106 354.9 25.0 6.1e-106 354.6 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE30675.1 - 4.3e-18 65.1 40.4 4.8e-15 55.1 7.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily zf-CCHC PF00098.18 EPE30676.1 - 7.5e-43 142.4 80.1 3.9e-06 26.5 0.2 10.4 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_4 PF14392.1 EPE30676.1 - 9.3e-05 22.0 67.3 0.26 10.9 0.4 10.3 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.1 EPE30676.1 - 0.0063 15.9 53.8 0.014 14.8 0.3 9.1 6 3 4 10 10 10 6 Zinc knuckle zf-CCHC_6 PF15288.1 EPE30676.1 - 0.065 12.9 0.3 0.065 12.9 0.2 9.6 8 2 1 9 9 9 0 Zinc knuckle Aldo_ket_red PF00248.16 EPE30677.1 - 1.3e-62 211.1 0.0 1.6e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4293 PF14126.1 EPE30678.1 - 0.058 13.3 0.1 0.077 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Tbf5 PF06331.7 EPE30679.1 - 1e-22 79.6 1.1 1.1e-22 79.5 0.8 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Unstab_antitox PF09720.5 EPE30679.1 - 0.11 12.1 1.2 0.73 9.5 0.8 1.9 1 1 0 1 1 1 0 Putative addiction module component Ribosomal_L16 PF00252.13 EPE30680.1 - 7.2e-29 100.2 0.5 1.1e-28 99.6 0.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L16p/L10e MliC PF09864.4 EPE30680.1 - 0.13 12.0 0.0 0.46 10.2 0.0 1.9 1 1 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme RFC1 PF08519.7 EPE30681.1 - 1.2e-56 190.7 0.2 4.4e-56 188.9 0.0 2.1 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EPE30681.1 - 2.3e-10 40.4 0.0 6.9e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EPE30681.1 - 3.3e-09 37.0 1.1 3.5e-08 33.7 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EPE30681.1 - 7.3e-06 24.9 0.0 1.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EPE30681.1 - 0.00014 22.6 0.0 0.00014 22.6 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA_22 PF13401.1 EPE30681.1 - 0.00035 20.7 0.2 0.007 16.5 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EPE30681.1 - 0.00063 19.6 0.1 0.033 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPE30681.1 - 0.001 18.7 0.1 0.0031 17.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EPE30681.1 - 0.0053 17.0 0.0 0.0053 17.0 0.0 3.1 3 0 0 3 3 1 1 AAA domain AAA_16 PF13191.1 EPE30681.1 - 0.0093 15.9 0.0 0.04 13.9 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.1 EPE30681.1 - 0.014 14.7 0.2 0.9 8.9 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EPE30681.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EPE30681.1 - 0.039 12.9 0.1 0.098 11.6 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus DDE_Tnp_IS66 PF03050.9 EPE30681.1 - 0.056 12.6 2.0 10 5.2 0.0 3.0 2 0 0 2 2 2 0 Transposase IS66 family RNA_helicase PF00910.17 EPE30681.1 - 0.058 13.5 0.1 0.53 10.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 EPE30681.1 - 0.069 12.8 0.0 0.23 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3666 PF12408.3 EPE30681.1 - 0.075 12.1 0.0 0.19 10.8 0.0 1.7 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase AAA_28 PF13521.1 EPE30681.1 - 0.21 11.5 2.7 0.23 11.3 0.0 2.5 3 0 0 3 3 2 0 AAA domain WD40 PF00400.27 EPE30682.1 - 4e-60 197.6 26.4 1.2e-11 43.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EPE30682.1 - 7.9e-05 20.9 4.2 0.13 10.3 0.2 3.7 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EPE30682.1 - 0.014 13.7 0.1 2.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain FAD_binding_8 PF08022.7 EPE30683.1 - 1.4e-21 76.3 0.0 3.2e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EPE30683.1 - 1.8e-15 57.1 0.0 4.2e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPE30683.1 - 1.1e-09 38.4 8.5 1.1e-09 38.4 5.9 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.27 EPE30683.1 - 0.00049 19.2 0.3 0.0013 17.9 0.2 1.7 1 0 0 1 1 1 1 EF hand FAD_binding_6 PF00970.19 EPE30683.1 - 0.0037 17.3 0.0 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain EF-hand_6 PF13405.1 EPE30683.1 - 0.035 13.9 0.2 0.091 12.6 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain NAD_binding_1 PF00175.16 EPE30683.1 - 0.078 13.5 0.0 5.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain EF-hand_7 PF13499.1 EPE30683.1 - 0.081 13.0 0.9 0.27 11.3 0.5 1.7 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 EPE30683.1 - 0.16 11.3 0.1 0.35 10.2 0.1 1.6 1 0 0 1 1 1 0 EF hand GFA PF04828.9 EPE30684.1 - 8.7e-15 54.4 5.4 2.8e-09 36.7 0.2 2.6 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme EMP24_GP25L PF01105.19 EPE30685.1 - 8.8e-44 149.3 0.0 1e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 EPE30685.1 - 0.013 13.6 0.1 0.017 13.3 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Helicase_RecD PF05127.9 EPE30685.1 - 0.09 12.3 0.0 0.23 11.0 0.0 1.6 1 1 0 2 2 2 0 Helicase NPV_P10 PF05531.7 EPE30686.1 - 0.095 12.9 2.7 74 3.7 0.0 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF2422 PF10337.4 EPE30688.1 - 2.5e-60 204.5 1.5 2.5e-60 204.5 1.0 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EPE30688.1 - 1.3e-10 41.2 16.5 1.3e-10 41.2 11.4 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EPE30688.1 - 0.0019 17.8 0.0 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) PROL5-SMR PF15621.1 EPE30689.1 - 0.87 10.0 4.7 1.2 9.5 3.3 1.2 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family DUF2397 PF09660.5 EPE30690.1 - 0.93 8.0 6.7 0.93 8.0 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Het-C PF07217.6 EPE30691.1 - 3.7e-262 870.9 0.0 5.2e-262 870.4 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C RasGAP PF00616.14 EPE30691.1 - 0.079 12.6 0.3 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase NAD_binding_1 PF00175.16 EPE30692.1 - 9.8e-31 106.5 0.0 3.1e-30 104.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EPE30692.1 - 3.2e-24 84.9 0.0 5.8e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EPE30692.1 - 3.9e-08 33.3 0.0 0.00026 20.9 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain AAR2 PF05282.6 EPE30692.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 AAR2 protein FAD_binding_9 PF08021.6 EPE30692.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain AP3B1_C PF14796.1 EPE30692.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Acetyltransf_1 PF00583.19 EPE30693.1 - 1.6e-08 34.4 0.1 6.8e-08 32.4 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE30693.1 - 5.9e-08 32.7 0.0 2.3e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE30693.1 - 2.4e-06 27.6 0.0 5.2e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE30693.1 - 0.0049 16.7 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EPE30693.1 - 0.048 13.5 0.1 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peroxidase_2 PF01328.12 EPE30694.1 - 2.8e-49 167.5 0.8 3.3e-49 167.2 0.5 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 DUF2237 PF09996.4 EPE30695.1 - 6.1e-32 109.5 2.6 4e-31 106.9 1.8 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Dynein_light PF01221.13 EPE30697.1 - 1.1e-40 137.4 1.6 1.3e-40 137.2 1.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_M24 PF00557.19 EPE30697.1 - 0.01 15.4 0.0 0.012 15.2 0.0 1.0 1 0 0 1 1 1 0 Metallopeptidase family M24 Imm28 PF15574.1 EPE30697.1 - 0.082 12.4 0.1 0.12 11.9 0.1 1.4 1 1 0 1 1 1 0 Immunity protein 28 RRM_1 PF00076.17 EPE30698.1 - 5.7e-77 253.3 0.1 1.1e-18 66.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE30698.1 - 1.9e-62 207.1 0.1 2.4e-13 49.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE30698.1 - 5.3e-34 115.8 0.0 3.2e-09 36.4 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EPE30698.1 - 1.2e-07 31.4 0.0 0.64 9.8 0.0 5.4 4 1 0 4 4 4 3 Limkain b1 Nup35_RRM_2 PF14605.1 EPE30698.1 - 3.1e-07 30.0 0.0 0.39 10.5 0.0 3.7 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EPE30698.1 - 2.2e-05 24.2 2.0 0.53 10.1 0.0 4.7 4 1 1 5 5 5 2 RNA binding motif TEA PF01285.13 EPE30699.1 - 2e-23 83.2 0.5 1.3e-20 74.0 0.0 2.9 3 0 0 3 3 3 2 TEA/ATTS domain family CinA PF02464.12 EPE30701.1 - 2e-25 89.0 2.3 7.7e-25 87.1 0.2 2.0 2 0 0 2 2 2 2 Competence-damaged protein SSF PF00474.12 EPE30703.1 - 1.2e-17 63.6 33.8 3e-17 62.3 23.5 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family zf-trcl PF13451.1 EPE30704.1 - 0.052 13.1 2.3 0.052 13.1 1.6 1.8 2 0 0 2 2 2 0 Probable zinc-binding domain RecR PF02132.10 EPE30704.1 - 0.16 11.4 2.8 1.6 8.2 0.2 2.3 2 0 0 2 2 2 0 RecR protein Melibiase PF02065.13 EPE30705.1 - 3.4e-17 62.2 0.4 1.7e-14 53.3 0.0 2.1 1 1 1 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 EPE30705.1 - 0.00021 20.5 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 Glycoside hydrolase 97 Raffinose_syn PF05691.7 EPE30705.1 - 0.0017 15.9 0.0 0.0025 15.4 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Acetyltransf_7 PF13508.1 EPE30706.1 - 1.8e-13 50.4 0.1 2.4e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE30706.1 - 1.8e-11 43.9 0.1 2.6e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE30706.1 - 5.6e-09 36.1 0.0 7.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPE30706.1 - 1.9e-05 24.8 0.0 2.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPE30706.1 - 0.00065 19.6 0.1 0.0011 18.9 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE30706.1 - 0.00075 19.1 0.1 0.0025 17.5 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 EPE30706.1 - 0.0013 18.5 0.0 0.0043 16.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE30706.1 - 0.094 12.6 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Sugar_tr PF00083.19 EPE30707.1 - 1.5e-77 261.0 25.5 1.8e-77 260.8 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE30707.1 - 5.5e-16 58.2 54.4 6.4e-13 48.1 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE30707.1 - 0.00021 19.8 4.3 0.00021 19.8 3.0 3.8 2 2 2 4 4 4 3 MFS/sugar transport protein FA_desaturase PF00487.19 EPE30708.1 - 3.3e-13 49.6 25.7 3.5e-13 49.5 15.7 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Pribosyltran PF00156.22 EPE30710.1 - 5.3e-17 61.7 0.0 7.2e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPE30710.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 EPE30710.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 PRTase ComF-like WD40 PF00400.27 EPE30711.1 - 6.6e-22 76.5 11.2 8e-06 25.5 0.0 7.0 7 1 1 8 8 8 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EPE30711.1 - 0.012 15.0 0.3 0.31 10.4 0.2 2.3 1 1 0 1 1 1 0 PQQ-like domain Nup160 PF11715.3 EPE30711.1 - 0.11 10.5 1.2 1.1 7.3 0.2 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF1852 PF08908.6 EPE30711.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1852) Atg14 PF10186.4 EPE30712.1 - 7.1e-22 77.7 0.8 1.1e-21 77.1 0.6 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EPE30712.1 - 1.1e-06 28.0 0.0 2.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 Spc7 PF08317.6 EPE30712.1 - 0.21 10.2 7.3 0.33 9.5 5.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_assoc_C PF09821.4 EPE30712.1 - 0.24 11.6 1.0 1 9.6 0.3 2.2 2 1 1 3 3 3 0 C-terminal AAA-associated domain XFP_N PF09364.5 EPE30713.1 - 2e-181 602.6 0.0 2.5e-181 602.2 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EPE30713.1 - 3e-86 288.0 0.0 4.2e-86 287.5 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EPE30713.1 - 2.1e-82 275.0 0.0 4.3e-82 274.0 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase NACHT PF05729.7 EPE30716.1 - 2.3e-10 40.3 0.0 5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPE30716.1 - 5.7e-07 29.6 0.0 5.9e-06 26.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Ank_2 PF12796.2 EPE30716.1 - 0.00015 22.0 0.0 0.00049 20.3 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF2075 PF09848.4 EPE30716.1 - 0.00076 18.5 0.1 0.01 14.8 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Ank_4 PF13637.1 EPE30716.1 - 0.0022 18.4 0.0 0.034 14.6 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 EPE30716.1 - 0.0037 17.4 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE30716.1 - 0.0069 16.1 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EPE30716.1 - 0.01 16.0 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE30716.1 - 0.036 14.8 0.6 0.78 10.5 0.0 3.3 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.17 EPE30716.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase KIP1 PF07765.7 EPE30716.1 - 0.093 12.5 1.0 2.2 8.2 0.0 3.1 3 0 0 3 3 3 0 KIP1-like protein AAA_25 PF13481.1 EPE30716.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.1 EPE30716.1 - 1.2 9.6 8.3 3.9 8.0 0.9 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger SNF2_N PF00176.18 EPE30717.1 - 8e-63 212.0 0.0 1.2e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EPE30717.1 - 1.1e-05 24.9 0.0 2.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE30717.1 - 0.00024 20.8 0.0 0.0057 16.4 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE30717.1 - 0.00035 20.4 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ASXH PF13919.1 EPE30717.1 - 0.039 13.7 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Asx homology domain zf-RING_5 PF14634.1 EPE30717.1 - 0.085 12.5 13.6 0.21 11.3 9.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EPE30717.1 - 0.21 11.4 12.7 0.76 9.6 8.8 2.1 1 0 0 1 1 1 0 Ring finger domain zf-4CXXC_R1 PF10497.4 EPE30717.1 - 0.43 10.7 6.7 1.1 9.4 4.6 1.6 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4 PF00097.20 EPE30717.1 - 1.8 8.2 14.2 5.1 6.8 9.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CGI-121 PF08617.5 EPE30720.1 - 1.7e-49 167.6 0.0 2e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Fungal_trans PF04082.13 EPE30721.1 - 3.1e-14 52.4 2.5 6.1e-14 51.5 1.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE30721.1 - 1.1e-06 28.4 8.0 2e-06 27.5 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain He_PIG PF05345.7 EPE30722.1 - 7.4 6.6 19.9 10 6.2 4.6 3.0 2 0 0 2 2 2 0 Putative Ig domain Ank_2 PF12796.2 EPE30724.1 - 1.5e-56 188.7 17.5 7.3e-18 64.6 0.1 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EPE30724.1 - 4.7e-46 152.3 10.0 5.7e-07 29.0 0.1 9.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 EPE30724.1 - 3.4e-39 128.9 10.0 6.6e-05 22.7 0.2 10.2 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 EPE30724.1 - 1.2e-33 114.8 9.2 4.8e-08 33.3 0.1 7.3 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE30724.1 - 4.4e-32 109.3 5.9 5.1e-10 39.2 0.2 6.7 3 3 4 7 7 7 6 Ankyrin repeats (many copies) CorA PF01544.13 EPE30724.1 - 1.5e-11 43.9 1.0 4.2e-11 42.4 0.4 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF1198 PF06711.6 EPE30724.1 - 0.021 14.6 0.9 6.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) PRP1_N PF06424.7 EPE30724.1 - 0.71 10.1 10.3 0.026 14.8 2.6 1.9 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal IncA PF04156.9 EPE30724.1 - 5.2 6.6 8.6 1.5 8.3 3.4 1.9 1 1 1 2 2 2 0 IncA protein Esterase_phd PF10503.4 EPE30725.1 - 2.2e-21 76.1 0.3 3e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EPE30725.1 - 2.6e-06 26.8 0.5 4.2e-06 26.1 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE30725.1 - 5.1e-05 23.0 0.1 6.2e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE30725.1 - 0.00012 21.9 0.0 0.00028 20.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE30725.1 - 0.00014 21.4 0.3 0.00028 20.5 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EPE30725.1 - 0.028 13.8 0.1 0.067 12.6 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Patatin PF01734.17 EPE30725.1 - 0.035 14.0 0.1 0.054 13.4 0.1 1.4 1 0 0 1 1 1 0 Patatin-like phospholipase BAAT_C PF08840.6 EPE30725.1 - 0.11 12.1 0.6 0.18 11.4 0.4 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Glyco_hydro_61 PF03443.9 EPE30726.1 - 3.6e-48 164.2 0.3 4e-48 164.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ricin_B_lectin PF00652.17 EPE30727.1 - 3.1e-12 46.5 0.4 1.3e-11 44.5 0.3 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EPE30727.1 - 4.9e-07 30.0 0.3 2.1e-06 28.0 0.2 1.8 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like WSC PF01822.14 EPE30728.1 - 5e-63 209.0 65.9 2.4e-19 69.0 9.8 5.1 4 1 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 EPE30728.1 - 4.8e-24 84.7 0.0 4.2e-20 71.8 0.0 4.0 2 1 2 4 4 4 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EPE30728.1 - 8.5e-23 80.2 0.1 2.1e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyco_transf_28 PF03033.15 EPE30729.1 - 2.6e-21 75.8 0.1 2.7e-20 72.5 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EPE30729.1 - 1.7e-06 26.8 0.1 2.8e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EPE30729.1 - 0.00046 19.8 0.1 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 EPE30729.1 - 0.011 15.8 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 ATG C terminal domain Cutinase PF01083.17 EPE30730.1 - 1.8e-50 171.1 2.5 2e-50 171.0 1.7 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EPE30730.1 - 4.9e-05 22.8 0.2 6.2e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.20 EPE30730.1 - 0.00011 21.8 0.1 0.00015 21.4 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 EPE30730.1 - 0.00061 20.0 0.0 0.00088 19.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.3 EPE30730.1 - 0.00065 19.1 0.1 0.00088 18.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EPE30730.1 - 0.00087 19.0 0.3 0.0011 18.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE30730.1 - 0.0023 17.5 0.1 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EPE30730.1 - 0.02 14.4 0.4 0.035 13.6 0.3 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE30730.1 - 0.043 13.6 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family vATP-synt_E PF01991.13 EPE30730.1 - 0.047 12.9 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit SseC PF04888.7 EPE30730.1 - 0.18 11.0 2.6 0.22 10.7 1.8 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Phasin_2 PF09361.5 EPE30731.1 - 0.023 14.7 0.0 0.24 11.4 0.0 2.2 1 1 1 2 2 2 0 Phasin protein UPAR_LY6 PF00021.16 EPE30733.1 - 0.1 13.0 5.8 0.12 12.7 4.0 1.1 1 0 0 1 1 1 0 u-PAR/Ly-6 domain TF_Zn_Ribbon PF08271.7 EPE30733.1 - 0.11 11.8 0.6 0.19 11.0 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding CDC45 PF02724.9 EPE30734.1 - 0.00021 19.5 0.2 0.00027 19.1 0.1 1.1 1 0 0 1 1 1 1 CDC45-like protein RRN3 PF05327.6 EPE30734.1 - 0.13 10.3 3.3 0.19 9.7 2.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.1 EPE30734.1 - 1 9.7 8.1 1.9 8.8 5.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.13 EPE30735.1 - 8e-25 87.1 0.2 1.3e-24 86.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE30735.1 - 9.2e-10 38.2 11.4 1.6e-09 37.5 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Plectin PF00681.15 EPE30735.1 - 0.081 12.4 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Plectin repeat Tnp_zf-ribbon_2 PF13842.1 EPE30736.1 - 0.5 10.8 8.8 4.7 7.7 5.5 2.3 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Bax1-I PF01027.15 EPE30737.1 - 1.9e-34 119.0 13.2 3e-34 118.4 9.1 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FATC PF02260.15 EPE30737.1 - 0.088 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 FATC domain PMSR PF01625.16 EPE30738.1 - 5e-61 205.1 0.3 5.8e-61 204.9 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase SH3_1 PF00018.23 EPE30738.1 - 4.2 6.8 7.5 2.7 7.4 0.7 2.3 1 1 1 2 2 2 0 SH3 domain Peptidase_M50B PF13398.1 EPE30739.1 - 0.16 11.3 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Kinesin PF00225.18 EPE30740.1 - 1.8e-115 385.2 0.0 5.3e-115 383.7 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain AAA_33 PF13671.1 EPE30740.1 - 0.015 15.1 0.0 0.067 13.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain Aldedh PF00171.17 EPE30741.1 - 2.7e-155 517.2 0.0 3e-155 517.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPE30741.1 - 7.9e-08 31.4 0.0 1.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EPE30741.1 - 0.0026 17.0 0.0 0.0089 15.2 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) SnoaL_4 PF13577.1 EPE30742.1 - 3.5e-25 88.3 0.3 5.3e-25 87.7 0.2 1.3 1 0 0 1 1 1 1 SnoaL-like domain Amidohydro_2 PF04909.9 EPE30743.1 - 7.7e-38 130.6 0.0 1.1e-37 130.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase RPE65 PF03055.10 EPE30744.1 - 9.4e-130 433.4 0.0 1.1e-129 433.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Sex_peptide PF08138.6 EPE30745.1 - 0.021 14.6 0.1 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 Sex peptide (SP) family Epiglycanin_C PF14654.1 EPE30745.1 - 0.079 12.9 0.3 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region DUF4400 PF14348.1 EPE30745.1 - 0.082 12.2 0.0 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) DUF1122 PF06557.6 EPE30746.1 - 0.17 11.0 0.3 0.33 10.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) Cmc1 PF08583.5 EPE30747.1 - 2.1e-12 46.5 1.0 2.1e-12 46.5 0.7 2.8 1 1 2 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like Utp11 PF03998.8 EPE30748.1 - 3.7e-56 190.6 24.6 4.2e-56 190.4 17.1 1.0 1 0 0 1 1 1 1 Utp11 protein G_glu_transpept PF01019.16 EPE30750.1 - 4.9e-144 480.6 0.1 5.6e-144 480.4 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3844 PF12955.2 EPE30752.1 - 6.7e-30 103.2 2.4 6.7e-30 103.2 1.6 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) PAF-AH_p_II PF03403.8 EPE30753.1 - 7e-56 189.1 0.0 1.3e-52 178.4 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EPE30753.1 - 7e-10 38.8 0.1 2.7e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE30753.1 - 5.4e-07 29.7 0.0 1.8e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EPE30753.1 - 0.00092 18.1 0.1 0.0028 16.5 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPE30753.1 - 0.0021 16.9 0.0 0.004 15.9 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Integrase_AP2 PF14657.1 EPE30755.1 - 0.051 13.3 3.9 0.11 12.2 2.7 1.5 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain Aldo_ket_red PF00248.16 EPE30756.1 - 8.6e-47 159.2 0.0 1e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 EPE30757.1 - 8.1e-46 152.9 54.5 8.6e-10 38.0 1.5 6.9 2 2 7 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE30757.1 - 3.7e-26 90.6 39.8 2.2e-09 36.9 2.3 5.3 2 1 5 7 7 7 6 Leucine rich repeat LRR_7 PF13504.1 EPE30757.1 - 2.3e-14 50.9 14.3 0.2 11.9 0.0 9.3 9 1 1 10 10 10 3 Leucine rich repeat LRR_6 PF13516.1 EPE30757.1 - 2.6e-14 51.6 21.9 0.039 14.0 0.4 10.2 5 4 5 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.28 EPE30757.1 - 4e-14 50.4 23.1 0.11 12.6 0.0 10.5 10 1 0 10 10 10 4 Leucine Rich Repeat LRR_9 PF14580.1 EPE30757.1 - 2.4e-11 43.5 17.3 2.7e-06 27.0 1.4 3.3 1 1 4 5 5 5 5 Leucine-rich repeat Abhydrolase_5 PF12695.2 EPE30758.1 - 1.4e-09 37.8 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE30758.1 - 3.6e-07 30.2 0.0 8.3e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EPE30758.1 - 0.17 11.0 0.4 5.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase MiAMP1 PF09117.5 EPE30759.1 - 0.053 13.9 0.6 0.072 13.5 0.4 1.4 1 0 0 1 1 1 0 MiAMP1 SnoaL_2 PF12680.2 EPE30760.1 - 3.7e-08 33.6 0.0 4.5e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain BTB PF00651.26 EPE30761.1 - 6.2e-09 35.8 0.0 2.2e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Sperm_Ag_HE2 PF05324.8 EPE30761.1 - 0.21 11.5 1.0 1.7 8.6 0.7 2.3 2 0 0 2 2 2 0 Sperm antigen HE2 PCI PF01399.22 EPE30762.1 - 1.5e-09 38.1 0.0 4.8e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 PCI domain Ribosomal_L18ae PF01775.12 EPE30763.1 - 1.2e-59 199.6 0.6 1.5e-59 199.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DNA_pol_A_exo1 PF01612.15 EPE30764.1 - 0.002 17.6 0.0 0.12 11.8 0.0 2.2 1 1 1 2 2 2 2 3'-5' exonuclease Radical_SAM PF04055.16 EPE30764.1 - 0.07 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily SAD_SRA PF02182.12 EPE30765.1 - 8.6e-23 80.3 0.0 1.7e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain Queuosine_synth PF02547.10 EPE30767.1 - 0.038 12.7 1.1 0.045 12.4 0.8 1.0 1 0 0 1 1 1 0 Queuosine biosynthesis protein DUF4598 PF15370.1 EPE30767.1 - 0.75 10.1 3.5 0.92 9.8 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) MFS_1 PF07690.11 EPE30769.1 - 1.4e-29 102.8 46.6 1.4e-29 102.8 32.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily HTH_17 PF12728.2 EPE30770.1 - 0.019 15.2 0.1 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Peptidase_M19 PF01244.16 EPE30771.1 - 4.6e-96 321.5 0.1 5.3e-96 321.3 0.1 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Methyltransf_23 PF13489.1 EPE30772.1 - 2.5e-08 33.8 0.0 3.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE30772.1 - 1.8e-05 24.3 0.0 4.3e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE30772.1 - 0.00077 19.8 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE30772.1 - 0.0077 16.6 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EPE30772.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.1 EPE30773.1 - 7.8e-09 35.4 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE30773.1 - 1.1e-05 25.9 0.0 2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE30773.1 - 1.8e-05 24.3 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE30773.1 - 8.3e-05 23.0 0.0 0.00014 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE30773.1 - 0.00073 19.9 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EPE30773.1 - 0.0017 17.6 0.0 0.0073 15.6 0.0 1.9 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.12 EPE30773.1 - 0.0074 15.3 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_PK PF05891.7 EPE30773.1 - 0.011 15.0 0.0 0.029 13.6 0.0 1.7 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase HRXXH PF13933.1 EPE30776.1 - 0.00082 18.8 0.0 0.0036 16.7 0.1 1.8 2 0 0 2 2 2 1 Putative peptidase family Aspzincin_M35 PF14521.1 EPE30776.1 - 0.027 14.9 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase SET PF00856.23 EPE30777.1 - 8e-13 49.0 0.0 4.4e-12 46.6 0.0 2.1 1 1 0 1 1 1 1 SET domain Gon7 PF08738.5 EPE30777.1 - 2.3 8.2 5.2 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 Gon7 family NIF PF03031.13 EPE30780.1 - 1.1e-50 171.3 0.2 1.7e-50 170.7 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec61_beta PF03911.11 EPE30780.1 - 2e-19 69.0 2.4 3.6e-19 68.2 1.7 1.4 1 0 0 1 1 1 1 Sec61beta family ABC_membrane_2 PF06472.10 EPE30782.1 - 7.5e-97 323.8 0.1 7.5e-97 323.8 0.1 2.1 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EPE30782.1 - 2e-15 57.3 0.0 5.6e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EPE30782.1 - 0.019 14.4 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EPE30782.1 - 0.027 14.4 0.0 0.12 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain T2SF PF00482.18 EPE30782.1 - 0.037 13.9 0.1 0.15 11.9 0.1 2.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Sigma54_activ_2 PF14532.1 EPE30782.1 - 0.064 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EPE30782.1 - 0.069 12.3 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EPE30782.1 - 0.079 12.9 0.1 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EPE30782.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EPE30782.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 EPE30782.1 - 0.45 10.7 4.4 4.3 7.6 3.0 2.2 1 1 0 1 1 1 0 AAA domain Glyco_hydro_72 PF03198.9 EPE30783.1 - 1.3e-118 395.5 0.2 1.7e-118 395.2 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EPE30783.1 - 2.2e-18 66.4 1.9 5.8e-18 65.1 1.3 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EPE30783.1 - 0.054 12.3 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Pectinesterase PF01095.14 EPE30784.1 - 1.2e-31 109.3 0.4 3.8e-26 91.3 0.6 2.1 1 1 0 2 2 2 2 Pectinesterase Perilipin PF03036.11 EPE30785.1 - 0.14 10.9 0.5 0.14 10.9 0.3 1.1 1 0 0 1 1 1 0 Perilipin family Chlorosome_CsmC PF11098.3 EPE30785.1 - 0.15 11.7 10.1 0.18 11.4 7.0 1.1 1 0 0 1 1 1 0 Chlorosome envelope protein C zinc_ribbon_5 PF13719.1 EPE30786.1 - 0.63 9.6 3.7 1.4 8.5 2.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Endostatin PF06482.6 EPE30787.1 - 0.0088 15.4 7.0 0.012 15.0 4.9 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin eIF-3_zeta PF05091.7 EPE30787.1 - 0.8 8.2 17.1 1 7.9 11.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3513 PF12026.3 EPE30787.1 - 0.83 9.1 13.7 0.99 8.9 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) PAT1 PF09770.4 EPE30787.1 - 1.3 7.1 29.9 1.4 7.0 20.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.10 EPE30787.1 - 3.1 6.9 16.4 3.4 6.8 11.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ycf1 PF05758.7 EPE30787.1 - 4.6 4.8 12.5 5.1 4.6 8.7 1.0 1 0 0 1 1 1 0 Ycf1 TFIIA PF03153.8 EPE30787.1 - 8.7 6.1 23.3 9.4 6.0 16.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4551 PF15087.1 EPE30787.1 - 8.8 4.5 10.2 9.8 4.4 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Abhydrolase_6 PF12697.2 EPE30790.1 - 4e-05 23.6 0.4 6.9e-05 22.8 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPE30790.1 - 9.1e-05 22.1 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPE30790.1 - 0.00031 20.5 0.0 0.00073 19.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EPE30790.1 - 0.0062 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2305 PF10230.4 EPE30790.1 - 0.034 13.5 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 EPE30790.1 - 0.19 11.0 0.1 0.4 9.9 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3659 PF12396.3 EPE30791.1 - 1.3e-12 47.2 8.7 3.9e-12 45.6 6.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) DUF883 PF05957.8 EPE30791.1 - 8.2 6.9 64.6 1.8 9.0 6.7 9.4 3 3 6 9 9 9 0 Bacterial protein of unknown function (DUF883) DUF3659 PF12396.3 EPE30792.1 - 6.4e-181 586.2 91.3 7e-25 86.4 3.1 10.6 10 0 0 10 10 10 10 Protein of unknown function (DUF3659) Trypan_PARP PF05887.6 EPE30792.1 - 0.0066 16.2 9.8 0.0066 16.2 6.8 8.1 6 1 0 6 6 6 1 Procyclic acidic repetitive protein (PARP) 2C_adapt PF08793.5 EPE30792.1 - 0.085 12.7 0.3 0.43 10.5 0.1 2.3 2 0 0 2 2 2 0 2-cysteine adaptor domain CCDC155 PF14662.1 EPE30792.1 - 0.088 12.3 5.6 0.017 14.7 1.1 1.7 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Sugar_tr PF00083.19 EPE30793.1 - 3e-94 316.1 27.0 3.5e-94 315.9 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE30793.1 - 1.9e-31 109.0 26.4 4.1e-26 91.5 5.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE30793.1 - 9.3e-05 20.9 31.8 0.012 14.0 8.6 3.5 1 1 2 3 3 3 2 MFS/sugar transport protein DUF3671 PF12420.3 EPE30793.1 - 1.8 8.5 11.1 13 5.8 0.3 3.6 2 1 0 2 2 2 0 Protein of unknown function Pectinesterase PF01095.14 EPE30794.1 - 1.3e-53 181.5 10.4 1.6e-53 181.2 7.2 1.1 1 0 0 1 1 1 1 Pectinesterase Adeno_E1B_55K PF01696.12 EPE30794.1 - 0.12 10.8 0.7 0.15 10.4 0.5 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Histidinol_dh PF00815.15 EPE30797.1 - 1.3e-178 593.8 2.8 2.3e-178 593.0 1.9 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EPE30797.1 - 3.9e-27 93.7 0.1 7.6e-27 92.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EPE30797.1 - 4.7e-10 39.6 0.7 1.1e-09 38.4 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase TFIID-31kDa PF02291.10 EPE30798.1 - 4.2e-24 84.7 0.0 2e-23 82.5 0.0 1.8 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit FAD_oxidored PF12831.2 EPE30799.1 - 0.015 14.3 0.6 0.036 13.1 0.1 1.6 1 1 1 2 2 2 0 FAD dependent oxidoreductase HNF-1A_C PF04813.7 EPE30799.1 - 0.051 13.8 0.9 0.16 12.2 0.1 2.3 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus RNA_pol_Rpb1_1 PF04997.7 EPE30800.1 - 8e-114 380.4 0.0 1.2e-113 379.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EPE30800.1 - 4.7e-103 344.2 0.1 7.8e-103 343.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPE30800.1 - 8.9e-71 237.1 0.0 1.7e-70 236.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EPE30800.1 - 4.6e-62 209.0 2.8 7.7e-62 208.3 1.9 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EPE30800.1 - 8.8e-48 162.0 0.0 2e-47 160.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EPE30800.1 - 1.7e-39 134.6 5.7 1.7e-39 134.6 3.9 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EPE30800.1 - 6.7e-38 128.7 0.1 1.5e-37 127.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EPE30800.1 - 8.5e-07 28.5 203.5 0.023 14.8 7.1 14.6 11 3 6 17 17 17 12 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.27 EPE30801.1 - 9.8e-08 31.5 9.2 1.3e-05 24.9 0.7 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.6 EPE30801.1 - 1.5e-06 28.0 0.2 0.082 12.6 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EPE30801.1 - 0.0031 15.8 0.2 0.31 9.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Peroxidase_2 PF01328.12 EPE30802.1 - 1.8e-10 40.0 1.5 4.1e-10 38.8 1.1 1.6 1 1 0 1 1 1 1 Peroxidase, family 2 dCMP_cyt_deam_1 PF00383.17 EPE30804.1 - 4.4e-07 29.4 0.1 6.3e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Rad1 PF02144.11 EPE30805.1 - 1.5e-91 305.9 0.0 1.8e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Bromodomain PF00439.20 EPE30806.1 - 2.7e-24 84.9 0.5 5e-24 84.0 0.4 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EPE30806.1 - 2e-09 37.4 0.4 4.4e-09 36.3 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE30806.1 - 4.8e-09 36.1 0.1 1.1e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPE30806.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein PTS_EIIC PF02378.13 EPE30807.1 - 0.0069 15.2 0.9 0.013 14.3 0.6 1.4 1 0 0 1 1 1 1 Phosphotransferase system, EIIC MR_MLE_C PF13378.1 EPE30808.1 - 5.7e-35 119.6 0.3 1e-34 118.8 0.2 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EPE30808.1 - 3.4e-17 62.5 0.0 7.2e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EPE30808.1 - 3e-10 40.4 0.0 7.5e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain CN_hydrolase PF00795.17 EPE30811.1 - 5.5e-34 117.1 0.0 6.9e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.13 EPE30812.1 - 0.0018 17.1 0.0 0.0036 16.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF605 PF04652.11 EPE30812.1 - 8.9 5.5 16.8 16 4.7 11.6 1.3 1 0 0 1 1 1 0 Vta1 like COesterase PF00135.23 EPE30813.1 - 3.5e-91 306.5 0.0 4.4e-91 306.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE30813.1 - 0.00096 18.7 0.0 0.006 16.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cellulase PF00150.13 EPE30815.1 - 1.7e-20 73.3 7.5 2.9e-19 69.3 5.2 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_53 PF07745.8 EPE30815.1 - 0.00055 18.8 1.0 0.00085 18.2 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Glyco_hydro_42 PF02449.10 EPE30815.1 - 0.027 13.5 0.6 0.15 11.1 0.0 2.2 3 0 0 3 3 3 0 Beta-galactosidase AAA PF00004.24 EPE30816.1 - 2e-20 73.3 0.0 1.1e-19 70.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE30816.1 - 0.0025 17.9 0.1 0.042 13.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EPE30816.1 - 0.003 17.0 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.1 EPE30816.1 - 0.0034 17.1 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EPE30816.1 - 0.011 15.7 0.7 0.032 14.2 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.13 EPE30816.1 - 0.015 14.8 0.0 0.036 13.5 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 EPE30816.1 - 0.029 14.0 0.0 0.19 11.3 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_33 PF13671.1 EPE30816.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPE30816.1 - 0.074 13.8 0.7 0.32 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EPE30816.1 - 0.078 13.2 1.1 0.33 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.4 EPE30816.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain 2OG-FeII_Oxy PF03171.15 EPE30817.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.7 EPE30818.1 - 2e-61 206.7 0.1 2.9e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EPE30818.1 - 0.015 15.3 0.1 0.054 13.5 0.0 1.9 2 0 0 2 2 2 0 Fascin domain Alpha_E2_glycop PF00943.14 EPE30818.1 - 0.14 10.7 0.0 0.25 9.9 0.0 1.3 1 1 0 1 1 1 0 Alphavirus E2 glycoprotein WD40 PF00400.27 EPE30819.1 - 1.8e-11 43.4 3.6 4.4e-05 23.1 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EPE30819.1 - 0.087 11.0 0.0 0.4 8.9 0.0 1.8 1 1 1 2 2 2 0 Cytochrome D1 heme domain Sel1 PF08238.7 EPE30820.1 - 2.8e-32 110.3 40.9 0.00011 22.7 0.1 13.7 13 1 0 13 13 13 9 Sel1 repeat TPR_11 PF13414.1 EPE30820.1 - 0.00061 19.3 11.1 0.0025 17.4 0.1 5.1 4 1 1 5 5 5 1 TPR repeat TPR_14 PF13428.1 EPE30820.1 - 0.00089 19.6 8.2 11 7.0 0.2 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPE30820.1 - 0.084 13.5 24.5 1.6 9.4 0.2 7.4 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPE30820.1 - 0.13 12.1 1.7 18 5.4 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Xan_ur_permease PF00860.15 EPE30821.1 - 1.9e-22 79.3 30.4 9.4e-22 77.0 19.2 2.7 2 1 0 2 2 2 2 Permease family Mei5 PF10376.4 EPE30822.1 - 0.0018 17.8 12.4 0.0079 15.7 8.4 2.0 1 1 0 1 1 1 1 Double-strand recombination repair protein DUF1444 PF07285.6 EPE30822.1 - 0.015 14.6 0.4 0.024 13.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) DUF4597 PF15366.1 EPE30822.1 - 0.38 10.3 2.4 8.7 6.0 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Amidohydro_1 PF01979.15 EPE30823.1 - 3e-60 204.6 1.5 6e-60 203.6 1.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EPE30823.1 - 1.7e-51 173.4 3.3 1.8e-51 173.3 1.3 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EPE30823.1 - 7.4e-43 144.4 0.5 1.5e-42 143.5 0.1 1.7 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EPE30823.1 - 2.5e-38 130.0 0.2 7.3e-38 128.5 0.0 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EPE30823.1 - 3.4e-06 26.7 2.4 1.1e-05 25.1 1.7 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPE30823.1 - 7.2e-05 22.1 0.3 0.00024 20.4 0.0 2.0 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.9 EPE30823.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 Amidohydrolase zf-RING_2 PF13639.1 EPE30824.1 - 3.7e-12 45.8 4.4 8.3e-12 44.7 3.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE30824.1 - 6e-07 29.3 5.2 1.6e-06 28.0 3.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE30824.1 - 6.7e-07 28.9 3.5 1.3e-06 28.0 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE30824.1 - 8.2e-07 28.5 4.2 2.1e-06 27.2 2.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE30824.1 - 0.00025 21.1 2.1 0.00061 19.8 1.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EPE30824.1 - 0.00062 19.3 5.1 0.0012 18.4 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPE30824.1 - 0.0017 18.0 2.0 0.0019 17.8 0.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EPE30824.1 - 0.035 13.9 2.3 0.076 12.8 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EPE30824.1 - 0.3 10.6 4.6 0.7 9.4 3.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EPE30824.1 - 0.54 10.1 10.0 1.1 9.2 6.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ada3 PF10198.4 EPE30825.1 - 1.1e-43 148.1 0.1 1.1e-43 148.1 0.1 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Lactamase_B_2 PF12706.2 EPE30826.1 - 1.4e-09 37.8 0.0 2.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 EPE30826.1 - 2e-06 27.8 0.0 4.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 EPE30826.1 - 3.8e-06 26.6 0.0 6.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EPE30826.1 - 0.041 13.7 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase Glyco_tranf_2_3 PF13641.1 EPE30827.1 - 5.1e-20 72.2 0.0 7.8e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EPE30827.1 - 3.2e-08 33.4 0.0 1.5e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EPE30827.1 - 1e-06 28.1 0.0 3.8e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Tic20 PF09685.5 EPE30827.1 - 0.00082 19.3 2.1 0.0016 18.4 1.5 1.4 1 0 0 1 1 1 1 Tic20-like protein DUF420 PF04238.7 EPE30827.1 - 0.0015 18.4 1.2 0.0029 17.5 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF420) DNA_pol3_a_NII PF11490.3 EPE30829.1 - 2.7 7.6 7.0 5 6.7 4.8 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II F-box PF00646.28 EPE30830.1 - 2.3e-06 27.0 0.0 6e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE30830.1 - 0.032 13.9 0.6 0.065 12.9 0.0 1.8 2 0 0 2 2 2 0 F-box-like Lipase_GDSL_2 PF13472.1 EPE30832.1 - 7.9e-10 39.1 0.7 1.4e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family HTH_OrfB_IS605 PF12323.3 EPE30832.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain SH3_3 PF08239.6 EPE30834.1 - 0.11 12.6 0.2 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Zn_clus PF00172.13 EPE30836.1 - 3.8e-07 29.8 11.7 3.8e-07 29.8 8.1 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE30836.1 - 5.3e-07 28.5 1.8 2.2e-06 26.5 0.2 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain FliJ PF02050.11 EPE30836.1 - 0.0076 16.2 3.2 0.0076 16.2 2.2 1.9 2 0 0 2 2 2 1 Flagellar FliJ protein SpaB_C PF14028.1 EPE30836.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 SpaB C-terminal domain Neisseria_TspB PF05616.8 EPE30836.1 - 0.31 9.3 3.6 0.53 8.5 2.5 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Cyanate_lyase PF02560.9 EPE30837.1 - 4e-29 99.9 0.0 5.7e-29 99.4 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.7 EPE30837.1 - 0.025 14.0 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.17 EPE30837.1 - 0.042 13.6 0.1 0.07 12.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix Chitin_bind_1 PF00187.14 EPE30838.1 - 1.1e-12 47.6 307.2 2.7e-05 24.0 16.0 13.5 11 2 2 13 13 13 11 Chitin recognition protein Glyco_hydro_18 PF00704.23 EPE30839.1 - 3.3e-64 217.4 0.8 5.2e-64 216.8 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_S8 PF00082.17 EPE30839.1 - 9e-15 54.5 0.0 9e-15 54.5 0.0 2.3 4 0 0 4 4 4 1 Subtilase family Chitin_bind_1 PF00187.14 EPE30839.1 - 2.1e-06 27.5 8.8 2.1e-06 27.5 6.1 4.3 5 0 0 5 5 5 2 Chitin recognition protein Metallophos_2 PF12850.2 EPE30841.1 - 1.5e-12 47.6 0.0 2.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EPE30841.1 - 7.4e-09 35.2 0.9 5.1e-08 32.5 0.6 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase BSP_II PF05432.6 EPE30842.1 - 0.25 10.6 11.8 0.28 10.4 8.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pex14_N PF04695.8 EPE30842.1 - 0.3 11.1 11.4 0.35 10.9 7.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4545 PF15078.1 EPE30842.1 - 0.52 9.1 4.3 0.54 9.1 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) Daxx PF03344.10 EPE30842.1 - 0.59 8.5 15.7 0.56 8.6 10.9 1.0 1 0 0 1 1 1 0 Daxx Family eIF-3_zeta PF05091.7 EPE30842.1 - 0.77 8.3 10.7 0.85 8.1 7.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.9 EPE30842.1 - 1.1 7.2 11.5 1.1 7.2 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 EPE30842.1 - 1.6 8.3 9.8 2.3 7.8 6.8 1.3 1 0 0 1 1 1 0 FAM176 family Vfa1 PF08432.5 EPE30842.1 - 1.8 8.5 11.7 2 8.4 8.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RP-C_C PF11800.3 EPE30842.1 - 1.9 8.1 7.4 1.9 8.1 5.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region AUX_IAA PF02309.11 EPE30842.1 - 2.1 8.0 7.8 2.8 7.6 5.4 1.3 1 0 0 1 1 1 0 AUX/IAA family Lin-8 PF03353.10 EPE30842.1 - 2.5 7.2 13.6 2.6 7.2 9.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Raftlin PF15250.1 EPE30842.1 - 2.6 6.4 9.2 2.7 6.4 6.4 1.0 1 0 0 1 1 1 0 Raftlin Spore_coat_CotO PF14153.1 EPE30842.1 - 2.9 7.3 16.3 3.3 7.0 11.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Myc_N PF01056.13 EPE30842.1 - 3.1 6.8 10.4 3.9 6.5 7.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region FAM60A PF15396.1 EPE30842.1 - 3.4 7.3 6.3 3.4 7.3 4.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.3 EPE30842.1 - 4.9 5.6 9.7 5 5.6 6.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TEX19 PF15553.1 EPE30842.1 - 5 6.9 11.0 6.9 6.5 7.6 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 XAP5 PF04921.9 EPE30842.1 - 5.9 6.3 10.8 7 6.1 7.5 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator DDHD PF02862.12 EPE30842.1 - 6.8 6.4 8.8 6.8 6.4 6.1 1.3 1 0 0 1 1 1 0 DDHD domain Merozoite_SPAM PF07133.6 EPE30842.1 - 7.4 6.4 18.6 11 5.9 12.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PIH1 PF08190.7 EPE30842.1 - 8.2 5.7 13.6 13 5.1 9.4 1.3 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Packaging_FI PF14000.1 EPE30842.1 - 8.9 6.5 11.3 14 5.8 7.8 1.3 1 0 0 1 1 1 0 DNA packaging protein FI CMAS PF02353.15 EPE30843.1 - 1.7e-18 66.6 0.0 3.6e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EPE30843.1 - 8.8e-17 61.2 0.0 1.3e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE30843.1 - 1.9e-13 50.2 0.0 4.8e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE30843.1 - 3.3e-13 49.9 0.0 6.6e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE30843.1 - 9.7e-12 45.4 0.0 2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE30843.1 - 2.6e-11 43.8 0.0 8.5e-11 42.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE30843.1 - 1.6e-09 38.0 0.0 3.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE30843.1 - 1.5e-07 31.4 0.0 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE30843.1 - 6.2e-06 25.6 0.1 7.2e-05 22.2 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 EPE30843.1 - 0.00012 21.4 0.1 0.0006 19.1 0.1 1.9 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MetW PF07021.7 EPE30843.1 - 0.0003 20.2 0.1 0.0034 16.7 0.1 2.3 2 1 1 3 3 3 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 EPE30843.1 - 0.0044 16.1 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EPE30843.1 - 0.0054 16.2 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 EPE30843.1 - 0.021 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.6 EPE30843.1 - 0.033 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DOT1 PF08123.8 EPE30843.1 - 0.074 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 FtsJ PF01728.14 EPE30843.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MFS_1 PF07690.11 EPE30844.1 - 4.1e-27 94.8 29.3 4.1e-27 94.8 20.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily PIG-L PF02585.12 EPE30846.1 - 3.5e-25 88.9 0.0 5.4e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase UPF0150 PF03681.10 EPE30846.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) GMC_oxred_C PF05199.8 EPE30847.1 - 6.9e-28 97.7 0.0 1.2e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EPE30847.1 - 1.5e-24 86.7 0.0 2.8e-21 75.9 0.0 3.0 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 EPE30847.1 - 0.00045 20.1 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE30847.1 - 0.0055 15.6 0.0 0.0077 15.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPE30847.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE30847.1 - 0.057 12.2 0.2 0.14 10.9 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EPE30847.1 - 0.2 10.6 0.1 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.14 EPE30848.1 - 3.6e-31 108.4 0.0 6.2e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE30848.1 - 3.4e-21 76.0 0.9 7.8e-21 74.8 0.6 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EPE30848.1 - 1.3e-07 30.8 0.2 4.5e-07 29.0 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE30848.1 - 0.00013 20.9 4.4 0.0042 16.0 0.1 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EPE30848.1 - 0.00065 18.2 0.8 0.0013 17.2 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EPE30848.1 - 0.0007 19.5 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPE30848.1 - 0.0026 17.8 0.1 0.14 12.1 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPE30848.1 - 0.0064 15.6 0.0 0.3 10.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE30848.1 - 0.0073 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EPE30848.1 - 0.0086 15.1 0.1 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EPE30848.1 - 0.014 15.2 0.4 0.11 12.3 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE30848.1 - 0.071 12.1 0.2 0.17 10.9 0.1 1.6 1 0 0 1 1 1 0 Thi4 family UreD PF01774.12 EPE30850.1 - 6.5e-55 185.8 0.0 8.4e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Fungal_trans PF04082.13 EPE30851.1 - 2.2e-20 72.6 0.2 4.6e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE30851.1 - 2.4e-06 27.3 11.1 4.2e-06 26.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 EPE30851.1 - 0.1 12.1 0.1 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 F-box-like PF12937.2 EPE30852.1 - 0.058 13.1 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 F-box-like SH3_9 PF14604.1 EPE30853.1 - 8.7e-32 108.4 3.4 2.1e-15 56.0 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EPE30853.1 - 1.2e-26 91.7 6.3 7.8e-13 47.5 0.4 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EPE30853.1 - 5.1e-16 57.9 0.1 1.1e-07 31.2 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 EPE30853.1 - 2.6e-11 43.5 0.0 4.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Glutaredoxin PF00462.19 EPE30855.1 - 1.8e-19 69.4 0.0 1.5e-18 66.4 0.0 2.3 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EPE30855.1 - 4.7e-13 48.7 0.0 1.1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EPE30855.1 - 0.088 12.9 0.1 4.5 7.4 0.0 2.8 3 1 1 4 4 4 0 Thioredoxin-like TrbC_Ftype PF09673.5 EPE30855.1 - 0.11 12.1 0.0 2.3 7.8 0.0 2.6 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin assembly protein ArsC PF03960.10 EPE30855.1 - 0.15 12.1 0.0 0.47 10.5 0.0 1.7 2 0 0 2 2 2 0 ArsC family TPR_12 PF13424.1 EPE30856.1 - 9.8e-14 51.0 7.7 4.5e-06 26.5 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.17 EPE30856.1 - 1e-11 44.2 0.1 2.2e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.1 EPE30856.1 - 2.8e-08 33.4 2.6 0.12 12.3 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_22 PF13401.1 EPE30856.1 - 5.8e-06 26.4 0.1 9.2e-05 22.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF676 PF05057.9 EPE30856.1 - 3.2e-05 23.3 0.0 5.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPE30856.1 - 0.00017 21.5 0.0 0.00087 19.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family TPR_1 PF00515.23 EPE30856.1 - 0.00034 20.1 0.2 0.062 12.9 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EPE30856.1 - 0.002 18.2 3.9 0.012 15.6 0.1 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EPE30856.1 - 0.0021 18.5 1.4 15 6.5 0.0 6.0 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPE30856.1 - 0.0058 16.2 1.1 0.15 11.7 0.1 3.1 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 EPE30856.1 - 0.011 15.6 3.6 0.84 9.7 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Lipase_3 PF01764.20 EPE30856.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) TPR_7 PF13176.1 EPE30856.1 - 0.027 14.2 4.5 27 4.9 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat ResIII PF04851.10 EPE30856.1 - 0.028 14.2 0.1 0.085 12.6 0.0 1.9 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit TPR_8 PF13181.1 EPE30856.1 - 0.048 13.4 3.1 0.91 9.4 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF829 PF05705.9 EPE30856.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Vps51 PF08700.6 EPE30856.1 - 0.086 12.6 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 Vps51/Vps67 Ank_2 PF12796.2 EPE30858.1 - 2.3e-12 47.0 0.0 4.1e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE30858.1 - 3.3e-12 45.5 0.8 5e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 EPE30858.1 - 4.9e-12 45.6 0.1 1.6e-11 44.0 0.1 2.0 1 0 0 1 1 1 1 IPT/TIG domain Ank_4 PF13637.1 EPE30858.1 - 7.4e-09 35.8 0.2 1.9e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE30858.1 - 4e-08 33.2 0.2 2.8e-06 27.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE30858.1 - 1.6e-07 30.8 0.2 0.011 15.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Na_H_Exchanger PF00999.16 EPE30859.1 - 1.5e-39 135.6 21.4 1.9e-39 135.2 14.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Vma12 PF11712.3 EPE30859.1 - 0.82 9.3 2.5 2.5 7.7 0.2 2.5 2 1 1 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cauli_VI PF01693.11 EPE30860.1 - 1.9e-33 114.2 10.2 9.6e-17 60.7 0.3 3.4 3 0 0 3 3 3 2 Caulimovirus viroplasmin RNase_H PF00075.19 EPE30860.1 - 1.1e-22 80.8 0.0 2.1e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 RNase H DUF3680 PF12441.3 EPE30860.1 - 0.13 12.1 1.1 2.4 8.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3680) 6PF2K PF01591.13 EPE30861.1 - 2.2e-69 232.9 0.0 1.3e-49 168.3 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPE30861.1 - 8.3e-24 84.4 0.0 3.8e-23 82.3 0.0 2.2 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EPE30861.1 - 3.8e-07 30.0 0.0 2e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPE30861.1 - 0.0013 18.0 0.0 0.034 13.3 0.0 2.2 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EPE30861.1 - 0.016 16.0 0.0 0.081 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain CARD PF00619.16 EPE30861.1 - 0.044 13.6 0.1 0.12 12.2 0.1 1.8 1 1 0 1 1 1 0 Caspase recruitment domain DUF1349 PF07081.6 EPE30862.1 - 1.9e-24 86.0 0.1 3.2e-24 85.2 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) Glyoxalase PF00903.20 EPE30865.1 - 9.8e-24 83.7 0.1 2.6e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EPE30865.1 - 3e-13 49.7 0.0 3.6e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EPE30865.1 - 2.5e-11 44.1 0.0 0.00017 22.1 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EPE30865.1 - 1.1e-07 31.9 0.0 0.014 15.3 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EPE30865.1 - 5.1e-05 23.2 0.1 0.0017 18.3 0.0 2.6 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Aida_N PF08910.5 EPE30865.1 - 0.044 14.0 0.2 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Aida N-terminus Dynactin_p22 PF07426.6 EPE30866.1 - 0.012 14.9 0.3 0.017 14.3 0.2 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 E1-E2_ATPase PF00122.15 EPE30867.1 - 2.4e-63 213.2 5.3 5.4e-63 212.0 3.7 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EPE30867.1 - 3e-23 83.3 0.0 6.7e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPE30867.1 - 4.2e-13 49.9 0.0 1.2e-12 48.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPE30867.1 - 1.2e-11 43.8 0.0 3.3e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPE30867.1 - 0.0013 18.3 0.1 0.0029 17.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPE30867.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit CBM_5_12_2 PF14600.1 EPE30868.1 - 0.56 9.8 4.1 13 5.5 0.2 2.7 2 0 0 2 2 2 0 Cellulose-binding domain Mito_carr PF00153.22 EPE30869.1 - 7.8e-27 92.8 7.8 3.5e-11 42.6 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 EPE30870.1 - 4.9e-103 344.5 0.0 6.6e-103 344.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EPE30870.1 - 0.0069 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Eclosion hormone RRM_1 PF00076.17 EPE30871.1 - 9.4e-09 34.7 0.0 1.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE30871.1 - 1.4e-08 34.4 0.0 2.2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE30871.1 - 8.1e-07 28.9 0.1 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EPE30871.1 - 7e-05 22.9 0.1 0.00019 21.5 0.1 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. MerR_1 PF13411.1 EPE30871.1 - 0.042 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 MerR HTH family regulatory protein WD40 PF00400.27 EPE30872.1 - 2.6e-06 27.0 8.6 0.082 12.8 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ABM PF03992.11 EPE30873.1 - 4.5e-05 23.3 0.0 6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase dCMP_cyt_deam_1 PF00383.17 EPE30875.1 - 4.1e-09 35.9 0.2 8.2e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EPE30875.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase PUF PF00806.14 EPE30876.1 - 9.6e-58 188.5 16.7 1.4e-08 33.7 0.3 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RNA_pol_Rpb2_6 PF00562.23 EPE30877.1 - 1.9e-115 385.6 0.2 3e-115 385.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPE30877.1 - 2.4e-51 173.5 0.2 4.7e-51 172.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EPE30877.1 - 1.5e-32 112.5 0.0 5.4e-32 110.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EPE30877.1 - 4.8e-28 97.2 0.6 1.2e-27 95.9 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EPE30877.1 - 3.4e-22 77.9 0.1 8e-22 76.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EPE30877.1 - 3.9e-20 71.3 0.0 7.7e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EPE30877.1 - 1.1e-08 34.9 0.3 3.1e-08 33.4 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Choline_transpo PF04515.7 EPE30878.1 - 3.6e-14 52.2 19.6 3.6e-14 52.2 13.6 3.2 3 1 1 4 4 4 2 Plasma-membrane choline transporter Ras PF00071.17 EPE30879.1 - 2.6e-49 166.7 0.0 1.1e-38 132.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EPE30879.1 - 4.6e-16 59.4 0.0 1.3e-15 57.8 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE30879.1 - 6.9e-13 48.2 0.0 3e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPE30879.1 - 7.2e-08 32.0 0.0 2.7e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPE30879.1 - 2.2e-06 27.0 0.0 4.8e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPE30879.1 - 0.00017 21.5 0.0 0.00031 20.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EPE30879.1 - 0.016 14.5 0.1 4 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EPE30879.1 - 0.018 15.1 0.0 0.071 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EPE30879.1 - 0.13 11.6 0.0 0.75 9.1 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EPE30879.1 - 0.16 11.9 0.1 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain WW PF00397.21 EPE30880.1 - 0.00028 20.6 2.6 0.00028 20.6 1.8 2.0 2 0 0 2 2 2 1 WW domain DUF2012 PF09430.5 EPE30881.1 - 3.6e-26 91.4 0.0 6.8e-26 90.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) DUF3465 PF11948.3 EPE30881.1 - 0.15 11.9 0.0 0.39 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3465) MARVEL PF01284.18 EPE30882.1 - 8.3e-25 87.2 15.7 1e-24 86.9 10.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain Cys_Met_Meta_PP PF01053.15 EPE30883.1 - 1.7e-149 497.3 0.0 2e-149 497.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EPE30883.1 - 5.3e-13 48.7 0.2 8.5e-13 48.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EPE30883.1 - 6e-08 32.0 0.0 1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPE30883.1 - 8.9e-07 27.9 0.1 1.5e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPE30883.1 - 2.1e-06 27.1 0.0 3.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EPE30883.1 - 0.0017 16.7 0.1 0.0022 16.3 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EPE30883.1 - 0.0092 14.7 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Sugar_tr PF00083.19 EPE30884.1 - 2.2e-73 247.3 19.3 2.7e-73 247.1 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE30884.1 - 4.2e-25 88.1 29.4 4.3e-22 78.3 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S5_C PF03719.10 EPE30884.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain PMT PF02366.13 EPE30885.1 - 1.5e-82 276.6 16.7 1.5e-82 276.6 11.6 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPE30885.1 - 1.4e-38 132.4 2.2 1.9e-38 131.9 1.5 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.3 EPE30885.1 - 0.9 9.1 8.5 0.03 13.8 0.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Sugar_tr PF00083.19 EPE30886.1 - 1.9e-99 333.3 15.1 2.2e-99 333.0 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE30886.1 - 2e-30 105.6 13.6 2e-30 105.6 9.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF791 PF05631.9 EPE30886.1 - 0.00029 19.6 1.7 0.00051 18.8 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 EPE30886.1 - 0.004 16.9 0.3 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 MFS_1 like family Chs3p PF12271.3 EPE30887.1 - 1.2e-101 339.5 7.1 1.6e-101 339.1 4.9 1.1 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit NADH-u_ox-rdase PF10785.4 EPE30887.1 - 0.28 11.4 1.6 3.3 8.0 0.3 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit YajC PF02699.10 EPE30887.1 - 1.5 8.5 0.0 1.5 8.5 0.0 2.5 3 0 0 3 3 3 0 Preprotein translocase subunit DUF973 PF06157.6 EPE30887.1 - 2.4 7.0 17.6 0.51 9.2 5.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF973) Ssl1 PF04056.9 EPE30888.1 - 1.3e-75 253.2 0.0 1.7e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EPE30888.1 - 2.2e-14 53.1 11.9 2.2e-14 53.1 8.3 3.1 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EPE30888.1 - 2e-06 28.0 0.0 3.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Fungal_trans PF04082.13 EPE30890.1 - 1.2e-08 34.2 7.3 3.4e-08 32.7 5.1 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE30890.1 - 3.1e-06 26.9 7.1 3.1e-06 26.9 4.9 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EPE30891.1 - 9.4e-21 74.2 0.9 5.1e-20 71.8 0.6 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE30891.1 - 3.2e-08 32.8 2.5 0.0015 17.5 0.4 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE30891.1 - 1.2e-06 28.3 0.1 3.4e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPE30891.1 - 4.7e-06 26.6 1.4 4.7e-05 23.3 0.4 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE30891.1 - 0.00013 20.9 0.2 0.00026 19.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EPE30891.1 - 0.00045 19.4 0.3 0.38 9.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EPE30891.1 - 0.00053 18.7 0.3 0.034 12.7 0.0 2.6 2 1 0 3 3 3 1 Tryptophan halogenase SE PF08491.5 EPE30891.1 - 0.0027 16.5 0.0 1.5 7.5 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Thi4 PF01946.12 EPE30891.1 - 0.0065 15.6 0.7 0.016 14.3 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EPE30891.1 - 0.012 15.6 0.1 0.025 14.6 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE30891.1 - 0.013 15.8 0.7 0.034 14.5 0.5 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE30891.1 - 0.017 13.5 0.4 0.039 12.4 0.3 1.7 1 1 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EPE30891.1 - 0.024 14.4 1.0 5.7 6.7 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EPE30891.1 - 0.043 12.7 0.4 4 6.2 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 EPE30891.1 - 0.082 12.9 0.5 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.17 EPE30891.1 - 0.14 11.0 1.9 3.1 6.5 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pkinase PF00069.20 EPE30892.1 - 5.9e-12 45.2 0.0 9.8e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30892.1 - 0.00014 21.0 0.0 0.006 15.6 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase RTA1 PF04479.8 EPE30893.1 - 6e-52 176.3 6.4 8.1e-52 175.9 4.4 1.1 1 0 0 1 1 1 1 RTA1 like protein PDR_CDR PF06422.7 EPE30893.1 - 0.073 12.7 1.0 0.43 10.2 0.0 2.6 3 0 0 3 3 3 0 CDR ABC transporter Zn_clus PF00172.13 EPE30894.1 - 1.1e-10 41.2 9.2 2.2e-10 40.2 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE30894.1 - 2.3e-05 23.2 0.2 3.8e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Velvet PF11754.3 EPE30895.1 - 5.4e-63 212.2 0.0 8.9e-63 211.5 0.0 1.3 1 0 0 1 1 1 1 Velvet factor E1-E2_ATPase PF00122.15 EPE30896.1 - 5.8 5.8 5.4 10 5.0 0.2 2.4 2 0 0 2 2 2 0 E1-E2 ATPase DUF1043 PF06295.7 EPE30897.1 - 0.39 10.3 3.3 1.4 8.5 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Pkinase PF00069.20 EPE30898.1 - 2.7e-17 62.7 0.0 6.4e-12 45.1 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30898.1 - 2.9e-09 36.3 0.0 0.052 12.6 0.0 4.0 2 2 1 3 3 3 3 Protein tyrosine kinase Rsd_AlgQ PF04353.8 EPE30898.1 - 2.7e-05 23.9 0.0 4.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Pkinase PF00069.20 EPE30899.1 - 1.3e-13 50.7 0.0 3.5e-13 49.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30899.1 - 6.1e-08 32.0 0.0 0.00019 20.5 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Vps54 PF07928.7 EPE30900.1 - 4.9e-39 133.5 0.6 1.4e-38 132.0 0.4 1.9 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EPE30900.1 - 9.9e-05 21.3 3.6 0.00028 19.8 2.5 1.7 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Pkinase PF00069.20 EPE30901.1 - 4.4e-06 26.0 0.0 1.2e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain AMP-binding PF00501.23 EPE30902.1 - 4.4e-71 239.4 0.0 5.7e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FAD_binding_3 PF01494.14 EPE30903.1 - 2.3e-23 82.8 0.0 8.3e-23 81.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE30903.1 - 4e-05 22.6 0.1 0.018 13.9 0.0 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPE30903.1 - 0.0084 15.9 0.0 0.019 14.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE30903.1 - 0.0087 16.0 0.0 0.036 14.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EPE30903.1 - 0.015 14.1 0.0 0.56 8.9 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Lycopene_cycl PF05834.7 EPE30903.1 - 0.053 12.4 0.1 0.12 11.3 0.1 1.8 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPE30903.1 - 0.095 11.5 0.1 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Viral_DNA_bp PF00747.12 EPE30905.1 - 0.49 7.5 2.6 0.69 7.0 1.8 1.1 1 0 0 1 1 1 0 ssDNA binding protein FYVE PF01363.16 EPE30905.1 - 1.1 9.2 15.0 0.2 11.5 7.5 2.1 2 0 0 2 2 2 0 FYVE zinc finger Vps39_2 PF10367.4 EPE30905.1 - 2.2 8.5 6.2 6 7.0 1.7 2.7 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 FYVE_2 PF02318.11 EPE30905.1 - 4.5 7.1 16.6 0.058 13.2 4.4 2.5 1 1 1 2 2 2 0 FYVE-type zinc finger DUF605 PF04652.11 EPE30906.1 - 0.68 9.2 13.7 0.79 9.0 9.5 1.1 1 0 0 1 1 1 0 Vta1 like Metallophos PF00149.23 EPE30907.1 - 0.014 14.8 0.2 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase p450 PF00067.17 EPE30908.1 - 4.8e-53 180.3 0.0 6.6e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 mit_SMPDase PF14724.1 EPE30908.1 - 0.057 11.2 0.0 0.086 10.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase Seadorna_VP7 PF07387.6 EPE30909.1 - 0.0006 18.7 0.0 0.0012 17.8 0.0 1.4 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.18 EPE30909.1 - 0.002 17.9 0.0 0.051 13.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EPE30909.1 - 0.038 13.1 0.0 0.067 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.17 EPE30909.1 - 0.042 13.1 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EPE30909.1 - 0.13 11.8 0.1 0.34 10.4 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase LRR_7 PF13504.1 EPE30910.1 - 0.19 12.0 7.5 2.4 8.7 0.0 5.1 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 EPE30910.1 - 1.8 8.8 4.6 40 4.7 0.1 4.4 5 1 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 EPE30910.1 - 8.8 6.7 6.8 16 6.0 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat NDT80_PhoG PF05224.7 EPE30911.1 - 2.3e-41 141.8 0.0 3e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family PetN PF03742.9 EPE30911.1 - 0.021 14.3 0.1 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 PetN Pyr_redox_3 PF13738.1 EPE30912.1 - 4.8e-20 72.5 0.0 9.2e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE30912.1 - 5.6e-10 38.0 0.1 1.6e-09 36.5 0.1 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EPE30912.1 - 1.9e-06 27.7 0.0 6.3e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EPE30912.1 - 0.0004 19.3 0.0 0.27 10.0 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EPE30912.1 - 0.00067 20.0 1.0 0.71 10.3 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE30912.1 - 0.0032 17.3 0.0 0.017 15.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE30912.1 - 0.0082 15.9 0.5 0.058 13.1 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EPE30912.1 - 0.0096 14.8 0.0 0.054 12.3 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPE30912.1 - 0.044 12.8 0.1 1 8.4 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.9 EPE30913.1 - 6.2e-07 28.4 0.0 1e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Tryptophan halogenase DAO PF01266.19 EPE30913.1 - 2.9e-05 23.1 0.0 4.5e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE30913.1 - 0.00051 20.0 0.0 0.00085 19.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPE30913.1 - 0.0064 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EPE30913.1 - 0.0079 16.5 0.0 0.089 13.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE30913.1 - 0.023 13.2 0.0 0.032 12.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EPE30913.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family zf-ribbon_3 PF13248.1 EPE30914.1 - 0.00023 20.2 1.5 0.00036 19.6 0.4 1.8 2 0 0 2 2 2 1 zinc-ribbon domain Lar_restr_allev PF14354.1 EPE30914.1 - 0.051 13.8 1.5 0.83 9.9 0.1 2.6 1 1 1 2 2 2 0 Restriction alleviation protein Lar HypA PF01155.14 EPE30914.1 - 0.1 12.3 0.2 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 EPE30914.1 - 0.45 10.0 2.7 0.46 10.0 0.6 2.0 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 EPE30914.1 - 0.46 10.2 3.9 0.72 9.6 0.2 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Beta_helix PF13229.1 EPE30915.1 - 3.3e-09 36.6 19.6 1.9e-07 30.9 8.7 2.8 2 1 1 3 3 3 2 Right handed beta helix region NosD PF05048.8 EPE30915.1 - 4.8e-06 25.8 11.8 0.0023 17.1 5.1 2.3 1 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) Chondroitinas_B PF14592.1 EPE30915.1 - 3.2e-05 22.9 0.3 6.2e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Chondroitinase B DUF1565 PF07602.6 EPE30915.1 - 0.00016 20.9 0.2 0.00016 20.9 0.1 2.5 3 1 1 4 4 4 1 Protein of unknown function (DUF1565) F-box-like PF12937.2 EPE30916.1 - 2.6e-07 30.2 0.0 6.6e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE30916.1 - 7.2e-06 25.5 0.0 1.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain PAPA-1 PF04795.7 EPE30916.1 - 0.41 11.3 8.7 6.1 7.6 2.6 2.9 2 0 0 2 2 2 0 PAPA-1-like conserved region DUF972 PF06156.8 EPE30916.1 - 1.2 9.4 10.1 5.8 7.3 0.6 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Amidohydro_1 PF01979.15 EPE30917.1 - 3.8e-15 56.3 0.0 9e-14 51.8 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EPE30917.1 - 1.1e-13 50.7 0.9 4.7e-13 48.7 0.2 2.6 3 1 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EPE30917.1 - 1.1e-07 31.4 0.9 9.7e-06 25.0 0.1 2.3 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EPE30917.1 - 2.5e-06 27.7 0.3 0.051 13.6 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase DUF1981 PF09324.5 EPE30917.1 - 0.092 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) adh_short PF00106.20 EPE30918.1 - 2.8e-08 33.8 0.0 7.4e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE30918.1 - 0.00013 21.6 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE30918.1 - 0.0036 17.1 0.3 0.0073 16.0 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Transglut_core PF01841.14 EPE30919.1 - 7.2e-12 45.5 0.0 2.5e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily Thioredoxin PF00085.15 EPE30919.1 - 2.2e-11 43.3 0.0 3.5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 EPE30919.1 - 0.0019 18.0 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain DUF553 PF04473.7 EPE30919.1 - 0.031 13.5 0.0 0.23 10.7 0.0 2.1 1 1 0 1 1 1 0 Transglutaminase-like domain NOGCT PF08155.6 EPE30921.1 - 0.015 14.9 0.3 0.04 13.6 0.2 1.6 1 0 0 1 1 1 0 NOGCT (NUC087) domain PINIT PF14324.1 EPE30922.1 - 0.087 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 PINIT domain AT_hook PF02178.14 EPE30922.1 - 5.2 7.0 9.9 0.33 10.7 2.2 2.7 2 0 0 2 2 2 0 AT hook motif DUF1675 PF07897.6 EPE30923.1 - 0.21 11.4 5.8 0.25 11.1 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Pox_Ag35 PF03286.9 EPE30923.1 - 4.7 6.6 10.6 6.4 6.2 7.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PDZ_1 PF12812.2 EPE30924.1 - 1.3e-57 191.5 0.0 1.3e-35 121.1 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EPE30924.1 - 4.2e-15 55.4 0.4 1.2e-05 25.1 0.0 4.5 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EPE30924.1 - 1.6e-14 53.8 0.3 5.2e-12 45.8 0.0 3.0 2 1 1 3 3 3 1 Trypsin-like peptidase domain PDZ PF00595.19 EPE30924.1 - 4e-10 39.7 0.0 9.5e-05 22.5 0.0 3.8 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EPE30924.1 - 9.1e-05 22.1 0.0 0.00025 20.7 0.0 1.7 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 EPE30924.1 - 0.0014 18.3 0.4 0.2 11.4 0.0 3.6 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EPE30924.1 - 0.1 11.9 0.2 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 EPE30924.1 - 0.19 11.0 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) EthD PF07110.6 EPE30925.1 - 0.00016 22.5 0.0 0.00025 21.9 0.0 1.4 1 1 0 1 1 1 1 EthD domain Fungal_trans PF04082.13 EPE30929.1 - 1.4e-27 96.2 0.0 2.1e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE30929.1 - 6.3e-09 35.5 11.3 1.1e-08 34.8 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE30930.1 - 3e-37 128.1 12.9 3e-37 128.1 9.0 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE30930.1 - 2.7e-09 36.1 1.3 2.7e-09 36.1 0.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF465 PF04325.8 EPE30930.1 - 0.063 12.9 0.7 0.095 12.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF465) DUF1014 PF06244.7 EPE30931.1 - 6.8e-18 65.0 17.0 6.8e-18 65.0 11.7 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) Fzo_mitofusin PF04799.8 EPE30931.1 - 0.033 13.5 0.4 0.056 12.8 0.3 1.3 1 0 0 1 1 1 0 fzo-like conserved region ELL PF10390.4 EPE30931.1 - 8.9 5.4 18.1 0.55 9.4 5.9 2.2 2 1 0 2 2 2 0 RNA polymerase II elongation factor ELL UQ_con PF00179.21 EPE30932.1 - 9.8e-08 31.5 1.4 1.7e-07 30.7 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPE30932.1 - 0.05 13.5 0.2 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 RWD domain GFA PF04828.9 EPE30934.1 - 1.7e-07 31.0 1.4 0.00011 22.1 0.0 3.1 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EPE30934.1 - 0.0039 16.3 5.2 0.66 9.2 0.0 3.5 3 0 0 3 3 3 2 zinc-ribbon domain NOB1_Zn_bind PF08772.6 EPE30934.1 - 1.3 8.9 0.0 1.3 8.9 0.0 3.7 4 0 0 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like Peptidase_S58 PF03576.9 EPE30935.1 - 7.9e-95 317.7 0.3 8.9e-95 317.6 0.2 1.0 1 0 0 1 1 1 1 Peptidase family S58 DUF3445 PF11927.3 EPE30936.1 - 1.9e-37 129.0 0.0 2.3e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) MIT PF04212.13 EPE30937.1 - 0.0041 16.9 0.0 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain VKG_Carbox PF05090.9 EPE30937.1 - 0.051 12.4 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase DEAD PF00270.24 EPE30938.1 - 1.3e-41 141.9 0.1 2.7e-41 140.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE30938.1 - 2.8e-23 81.5 0.3 1.3e-22 79.3 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE30938.1 - 0.00022 21.1 0.0 0.00052 19.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EPE30938.1 - 0.024 14.5 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain Glyco_hydro_10 PF00331.15 EPE30939.1 - 2.1e-86 289.8 0.7 2.4e-86 289.6 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 WD40 PF00400.27 EPE30940.1 - 3.4e-25 86.9 11.5 4.8e-08 32.5 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.1 EPE30941.1 - 8.6e-35 120.3 0.0 1.2e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 EPE30941.1 - 1.4e-08 34.5 4.5 2.6e-08 33.6 3.1 1.4 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 EPE30941.1 - 0.0037 17.5 0.0 0.0079 16.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3328 PF11807.3 EPE30942.1 - 6.5e-41 140.3 1.6 7.7e-41 140.1 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EPE30943.1 - 4.8e-40 137.5 0.7 6.1e-40 137.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PA14_2 PF10528.4 EPE30943.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 GLEYA domain BRF1 PF07741.8 EPE30944.1 - 0.0018 18.4 0.8 1.3 9.2 0.1 3.2 1 1 1 2 2 2 2 Brf1-like TBP-binding domain Phage_CI_repr PF07022.8 EPE30944.1 - 0.1 12.6 10.6 19 5.4 0.1 5.0 2 1 3 5 5 5 0 Bacteriophage CI repressor helix-turn-helix domain ketoacyl-synt PF00109.21 EPE30946.1 - 4.1e-75 252.5 0.0 1.2e-74 251.0 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 EPE30946.1 - 1.2e-71 241.3 0.0 1.8e-71 240.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EPE30946.1 - 3.1e-55 187.1 0.1 7.8e-55 185.8 0.0 1.7 2 0 0 2 2 2 1 Condensation domain Acyl_transf_1 PF00698.16 EPE30946.1 - 7e-52 176.7 0.0 1.4e-51 175.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EPE30946.1 - 3.2e-50 170.9 0.0 5.6e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EPE30946.1 - 6e-49 166.1 0.0 2.6e-47 160.8 0.0 2.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EPE30946.1 - 1.2e-40 139.1 0.0 4.4e-38 130.8 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EPE30946.1 - 7.6e-39 133.1 0.0 2.1e-37 128.4 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EPE30946.1 - 3.7e-32 110.6 0.0 9e-32 109.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EPE30946.1 - 1.1e-17 64.2 0.0 5.4e-17 62.0 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 EPE30946.1 - 3.9e-16 59.0 0.1 2.7e-08 33.9 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EPE30946.1 - 9.3e-16 57.9 0.0 4e-15 55.8 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.16 EPE30946.1 - 8.4e-14 51.5 0.0 1.3e-10 41.1 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EPE30946.1 - 7.6e-12 45.0 0.0 2.5e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EPE30946.1 - 1.4e-11 43.6 0.0 1.9e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family HxxPF_rpt PF13745.1 EPE30946.1 - 2e-11 44.0 0.1 2.1e-10 40.7 0.0 3.0 3 0 0 3 3 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 EPE30946.1 - 4.2e-11 43.1 0.0 1.3e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE30946.1 - 6.5e-09 36.3 0.0 3.3e-08 34.0 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE30946.1 - 4.8e-06 25.8 0.0 1.5e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AMP-binding_C PF13193.1 EPE30946.1 - 5.9e-06 27.1 0.1 2.5e-05 25.1 0.1 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 EPE30946.1 - 3.5e-05 22.9 0.0 7.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_24 PF13578.1 EPE30946.1 - 0.00024 21.9 0.0 0.074 13.8 0.0 3.6 3 0 0 3 3 2 1 Methyltransferase domain RrnaAD PF00398.15 EPE30946.1 - 0.011 14.8 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Shikimate_DH PF01488.15 EPE30946.1 - 0.033 14.2 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase NodS PF05401.6 EPE30946.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.14 EPE30946.1 - 0.14 11.6 0.1 0.67 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EPE30946.1 - 0.15 11.4 0.0 0.61 9.4 0.0 2.0 2 0 0 2 2 1 0 Methionine biosynthesis protein MetW Abhydrolase_6 PF12697.2 EPE30947.1 - 5.1e-09 36.3 0.1 9.1e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE30947.1 - 1.8e-08 34.2 0.0 6e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EPE30947.1 - 2.5e-06 26.3 0.0 3.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 EPE30947.1 - 4e-05 22.9 0.0 8.2e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EPE30947.1 - 0.0067 16.0 0.1 0.032 13.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_transf_43 PF03360.11 EPE30948.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 43 DUF1772 PF08592.6 EPE30950.1 - 0.0053 16.4 2.1 0.0053 16.4 1.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) COX6C PF02937.10 EPE30950.1 - 0.016 15.0 0.1 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc Amidohydro_1 PF01979.15 EPE30951.1 - 5.3e-27 95.3 3.8 2.2e-14 53.8 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EPE30951.1 - 3.7e-16 58.7 0.3 3.7e-16 58.7 0.2 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EPE30951.1 - 7.6e-10 39.2 1.9 0.00019 21.5 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EPE30951.1 - 1.9e-06 27.3 1.1 0.0015 17.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family W2 PF02020.13 EPE30951.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Zn_clus PF00172.13 EPE30952.1 - 0.00012 21.8 9.5 0.00022 21.0 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE30953.1 - 3.8e-41 140.9 54.7 3.8e-41 140.9 37.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily ADH_zinc_N PF00107.21 EPE30954.1 - 9.2e-10 38.1 0.0 1.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE30954.1 - 2.1e-06 27.4 0.3 6.6e-06 25.8 0.2 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF3586 PF12131.3 EPE30955.1 - 0.13 12.3 1.4 0.17 11.9 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3586) FAD_binding_4 PF01565.18 EPE30956.1 - 1.6e-24 85.9 0.5 3.9e-23 81.4 0.9 2.2 2 0 0 2 2 2 1 FAD binding domain ABC2_membrane PF01061.19 EPE30957.1 - 1.5e-93 311.7 57.7 2.3e-49 167.3 13.6 3.9 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EPE30957.1 - 1.2e-41 140.5 5.8 1.7e-36 123.9 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 EPE30957.1 - 8e-40 136.3 0.1 4.9e-19 68.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EPE30957.1 - 1.5e-17 63.4 0.1 6.2e-17 61.4 0.0 2.2 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EPE30957.1 - 1.2e-08 34.6 0.0 9.6e-06 25.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EPE30957.1 - 4e-07 30.1 0.2 0.00073 19.5 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EPE30957.1 - 1.8e-06 27.2 0.0 0.0017 17.5 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 EPE30957.1 - 2.4e-05 23.5 16.1 2.4e-05 23.5 11.2 4.0 2 2 1 3 3 3 1 ABC-2 family transporter protein cobW PF02492.14 EPE30957.1 - 5.1e-05 22.7 0.6 0.0043 16.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EPE30957.1 - 0.00014 21.3 0.3 0.037 13.5 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EPE30957.1 - 0.00016 21.5 0.1 0.035 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPE30957.1 - 0.00043 20.5 0.0 0.14 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE30957.1 - 0.0012 18.9 0.3 1 9.5 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPE30957.1 - 0.0014 19.4 0.0 0.22 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPE30957.1 - 0.0059 16.3 0.2 3 7.6 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain NACHT PF05729.7 EPE30957.1 - 0.0059 16.2 2.7 0.89 9.1 0.1 2.9 3 0 0 3 3 3 1 NACHT domain AAA_21 PF13304.1 EPE30957.1 - 0.0062 16.5 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EPE30957.1 - 0.0064 15.7 0.1 0.47 9.6 0.0 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.17 EPE30957.1 - 0.015 15.4 0.1 9.9 6.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 EPE30957.1 - 0.028 14.9 0.1 3.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 EPE30957.1 - 0.044 13.7 0.0 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EPE30957.1 - 0.056 13.0 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EPE30957.1 - 0.059 13.0 1.2 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EPE30957.1 - 0.064 12.7 0.2 0.89 8.9 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EPE30957.1 - 0.081 12.6 0.0 9 5.9 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 EPE30957.1 - 0.32 10.4 1.9 15 4.8 0.0 2.9 2 1 1 3 3 3 0 AAA-like domain XPA_C PF05181.7 EPE30959.1 - 3.3e-28 97.0 2.6 7.8e-28 95.8 1.8 1.7 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EPE30959.1 - 0.0028 17.2 0.5 0.0028 17.2 0.4 2.1 2 0 0 2 2 2 1 XPA protein N-terminal Vma12 PF11712.3 EPE30959.1 - 0.12 12.0 2.8 0.13 11.9 0.2 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ArfGap PF01412.13 EPE30959.1 - 5.1 6.9 6.7 1.4 8.7 0.1 2.9 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf Pho88 PF10032.4 EPE30960.1 - 7e-78 260.2 1.3 7.9e-78 260.0 0.9 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Striatin PF08232.7 EPE30961.1 - 5.9e-37 126.9 1.3 1.2e-36 125.9 0.9 1.6 1 0 0 1 1 1 1 Striatin family WD40 PF00400.27 EPE30961.1 - 1.9e-32 109.9 19.5 3.8e-07 29.7 0.1 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat ERM PF00769.14 EPE30961.1 - 0.019 14.4 4.0 0.035 13.6 2.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HET PF06985.6 EPE30962.1 - 1e-21 77.5 0.0 1.9e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PIG-P PF08510.7 EPE30963.1 - 7.9e-44 148.3 0.6 1.1e-43 147.9 0.4 1.2 1 0 0 1 1 1 1 PIG-P Nif11 PF07862.6 EPE30964.1 - 0.11 12.5 0.4 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function Abhydrolase_6 PF12697.2 EPE30965.1 - 6.1e-23 81.8 2.2 1.2e-22 80.9 1.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE30965.1 - 2e-13 50.3 0.0 4.4e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE30965.1 - 3.5e-05 23.5 0.0 0.00013 21.7 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EPE30965.1 - 0.031 13.5 2.1 0.054 12.7 1.4 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3494 PF11999.3 EPE30966.1 - 1.4e-33 116.2 20.3 1.7e-33 115.9 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Pro-kuma_activ PF09286.6 EPE30967.1 - 1.2e-41 142.0 0.2 2e-41 141.3 0.2 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EPE30967.1 - 4.3e-10 39.1 0.4 6.8e-10 38.5 0.3 1.2 1 0 0 1 1 1 1 Subtilase family Myb_DNA-bind_6 PF13921.1 EPE30968.1 - 3e-05 24.0 1.5 0.0026 17.8 0.2 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4512 PF14975.1 EPE30968.1 - 0.31 11.8 0.0 0.31 11.8 0.0 4.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4512) DS PF01916.12 EPE30969.1 - 7.9e-139 461.8 0.0 9.3e-139 461.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EPE30969.1 - 0.017 14.2 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 Carbamoyltransferase HSF_DNA-bind PF00447.12 EPE30970.1 - 2.2e-27 95.2 0.0 5.5e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding G-gamma PF00631.17 EPE30971.1 - 0.32 10.7 2.6 0.93 9.2 1.8 1.8 1 0 0 1 1 1 0 GGL domain DivIC PF04977.10 EPE30971.1 - 0.65 9.5 4.5 0.82 9.2 2.1 1.9 2 0 0 2 2 2 0 Septum formation initiator Val_tRNA-synt_C PF10458.4 EPE30971.1 - 8.3 6.5 10.9 0.69 10.0 3.7 1.9 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Pro_isomerase PF00160.16 EPE30972.1 - 6.3e-38 130.4 0.0 1.1e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LMWSLP_N PF12211.3 EPE30974.1 - 0.033 14.0 0.3 0.058 13.2 0.2 1.3 1 0 0 1 1 1 0 Low molecular weight S layer protein N terminal DUF3746 PF12562.3 EPE30974.1 - 1.1 9.1 6.6 4.6 7.1 4.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3746) Polyketide_cyc2 PF10604.4 EPE30975.1 - 0.002 18.3 0.0 0.0027 17.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AAA PF00004.24 EPE30976.1 - 2.3e-16 60.1 0.0 4.2e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EPE30976.1 - 3.2e-16 59.0 0.0 8.9e-16 57.6 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPE30976.1 - 4.2e-14 52.5 0.0 9e-14 51.4 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EPE30976.1 - 3.6e-10 39.1 0.0 4e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EPE30976.1 - 3e-07 30.6 0.0 1.1e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPE30976.1 - 1.9e-06 27.9 0.1 9.8e-05 22.4 0.0 2.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EPE30976.1 - 3.5e-06 26.7 0.3 8e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPE30976.1 - 4.6e-06 25.8 0.2 0.00012 21.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 EPE30976.1 - 7.4e-06 25.5 0.4 1.7e-05 24.4 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_5 PF07728.9 EPE30976.1 - 9.8e-06 25.3 0.1 3.4e-05 23.5 0.1 1.9 1 1 1 2 2 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPE30976.1 - 1e-05 25.1 0.0 2.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EPE30976.1 - 1.4e-05 24.0 0.4 0.13 10.9 0.0 3.0 2 1 1 3 3 3 2 TIP49 C-terminus AAA_11 PF13086.1 EPE30976.1 - 6.4e-05 22.6 0.3 0.00013 21.6 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPE30976.1 - 9e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EPE30976.1 - 0.00033 19.6 0.0 0.00059 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 EPE30976.1 - 0.0005 19.1 0.0 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 EPE30976.1 - 0.00062 19.4 0.0 0.0017 17.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.6 EPE30976.1 - 0.00079 19.0 0.1 0.0026 17.3 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EPE30976.1 - 0.0015 17.8 0.4 0.36 10.0 0.0 2.3 1 1 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.1 EPE30976.1 - 0.0021 17.4 0.3 0.046 13.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 EPE30976.1 - 0.0034 17.3 0.1 0.007 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain VTC PF09359.5 EPE30976.1 - 0.0058 15.6 0.3 0.0082 15.1 0.2 1.1 1 0 0 1 1 1 1 VTC domain AAA_10 PF12846.2 EPE30976.1 - 0.012 15.0 0.2 1 8.7 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EPE30976.1 - 0.013 16.3 0.0 0.026 15.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TK PF00265.13 EPE30976.1 - 0.013 15.0 0.2 0.082 12.4 0.0 2.0 2 0 0 2 2 2 0 Thymidine kinase IstB_IS21 PF01695.12 EPE30976.1 - 0.02 14.3 0.2 0.19 11.0 0.2 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein DEAD PF00270.24 EPE30976.1 - 0.026 14.0 0.1 0.22 10.9 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.13 EPE30976.1 - 0.031 13.7 0.1 0.099 12.1 0.0 1.9 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EPE30976.1 - 0.033 14.4 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EPE30976.1 - 0.042 12.9 0.1 0.26 10.4 0.0 2.4 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 EPE30976.1 - 0.066 13.0 0.0 0.27 11.0 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 EPE30976.1 - 0.071 12.9 0.4 0.2 11.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPE30976.1 - 0.077 13.1 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EPE30976.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase Flavi_DEAD PF07652.9 EPE30976.1 - 0.16 11.7 2.2 1.6 8.4 0.1 2.8 2 1 1 3 3 3 0 Flavivirus DEAD domain Glyco_hydro_61 PF03443.9 EPE30977.1 - 1e-77 260.8 1.3 1.3e-77 260.5 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Big_3_4 PF13754.1 EPE30977.1 - 0.047 14.0 0.7 0.047 14.0 0.5 2.9 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) Methyltransf_23 PF13489.1 EPE30978.1 - 2.9e-07 30.3 0.0 4.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE30978.1 - 0.0044 16.6 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Sigma70_ner PF04546.8 EPE30978.1 - 3.3 7.2 11.8 0.31 10.6 2.2 2.3 2 1 0 2 2 2 0 Sigma-70, non-essential region P21-Arc PF04062.9 EPE30979.1 - 1.6e-76 255.9 0.0 3e-38 131.3 0.0 2.0 1 1 1 2 2 2 2 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 EPE30979.1 - 0.11 12.4 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Pancreatic hormone peptide Gcd10p PF04189.8 EPE30980.1 - 6.9e-78 261.7 0.0 9.5e-78 261.3 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family DUF544 PF04424.8 EPE30981.1 - 6.7e-14 51.7 0.0 1.1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Glyco_hydro_16 PF00722.16 EPE30982.1 - 1.4e-10 40.7 0.3 6e-10 38.7 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 PAT1 PF09770.4 EPE30982.1 - 1.6 6.8 39.1 1.9 6.5 27.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF866 PF05907.8 EPE30984.1 - 1.1 8.7 5.3 0.29 10.6 0.9 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF866) IBR PF01485.16 EPE30984.1 - 6.5 6.6 23.7 0.36 10.7 2.6 3.4 1 1 1 2 2 2 0 IBR domain Copper-bind PF00127.15 EPE30987.1 - 8.5e-05 22.7 0.2 0.0002 21.5 0.2 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 EPE30987.1 - 0.001 18.8 0.5 0.0023 17.6 0.3 1.6 1 1 0 1 1 1 1 Plastocyanin-like domain Cytochrom_D1 PF02239.11 EPE30989.1 - 1.1e-05 23.9 2.9 6.7e-05 21.3 0.3 2.7 1 1 2 3 3 3 2 Cytochrome D1 heme domain SGL PF08450.7 EPE30989.1 - 2.6e-05 23.7 0.3 0.00044 19.7 0.0 2.8 2 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 EPE30989.1 - 5.7e-05 22.3 0.4 0.014 14.5 0.1 2.7 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller FlaG PF03646.10 EPE30989.1 - 0.018 15.1 1.2 0.21 11.7 0.1 2.6 2 0 0 2 2 2 0 FlaG protein DUF4221 PF13970.1 EPE30989.1 - 0.079 12.2 0.0 7.2 5.8 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4221) PD40 PF07676.7 EPE30990.1 - 2.2e-47 158.0 23.8 3.8e-10 39.1 0.3 10.6 9 1 1 10 10 10 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EPE30990.1 - 1.8e-09 36.6 5.3 0.034 12.7 0.0 6.3 5 1 1 6 6 6 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region SGL PF08450.7 EPE30990.1 - 0.026 13.8 3.2 0.34 10.2 0.2 3.7 2 2 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Bac_rhamnosid_N PF08531.5 EPE30990.1 - 0.041 13.3 0.0 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Alpha-L-rhamnosidase N-terminal domain Cytochrom_D1 PF02239.11 EPE30990.1 - 0.055 11.7 0.0 0.82 7.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40 PF00400.27 EPE30990.1 - 0.42 10.5 8.4 5.5 7.0 0.4 5.0 4 2 0 4 4 4 0 WD domain, G-beta repeat Herpes_gE PF02480.11 EPE30992.1 - 0.12 10.6 0.3 1.1 7.4 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E MMR_HSR1 PF01926.18 EPE30994.1 - 1.2e-08 34.8 0.0 3.7e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPE30994.1 - 1.1e-06 27.9 0.0 2.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EPE30994.1 - 0.00011 22.0 1.7 0.023 14.5 0.9 3.4 2 1 0 2 2 2 1 Dynamin family AIG1 PF04548.11 EPE30994.1 - 0.00029 20.0 0.0 0.48 9.4 0.0 2.5 2 0 0 2 2 2 2 AIG1 family FtsK_SpoIIIE PF01580.13 EPE30994.1 - 0.00046 19.7 0.0 0.0014 18.1 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EPE30994.1 - 0.0011 19.0 0.0 0.0077 16.2 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 EPE30994.1 - 0.0012 18.2 0.0 0.0031 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.13 EPE30994.1 - 0.002 17.1 0.1 0.0057 15.7 0.1 1.7 1 1 0 1 1 1 1 Septin AAA_23 PF13476.1 EPE30994.1 - 0.0033 17.7 2.9 0.0075 16.6 1.3 2.2 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EPE30994.1 - 0.0036 16.2 0.4 0.0098 14.8 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 EPE30994.1 - 0.0043 17.2 0.0 0.089 12.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain IIGP PF05049.8 EPE30994.1 - 0.0069 15.2 0.0 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EPE30994.1 - 0.011 16.0 0.7 0.095 12.9 0.0 2.9 3 1 1 4 4 3 0 ABC transporter AAA_10 PF12846.2 EPE30994.1 - 0.014 14.8 0.1 0.083 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 EPE30994.1 - 0.027 14.9 0.0 0.091 13.2 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein Sigma54_activat PF00158.21 EPE30994.1 - 0.044 13.2 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EPE30994.1 - 0.057 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Filament PF00038.16 EPE30996.1 - 0.071 12.5 53.6 0.023 14.1 6.0 3.4 2 2 1 3 3 3 0 Intermediate filament protein HET PF06985.6 EPE30997.1 - 4.2e-23 82.0 0.0 9.5e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 EPE30997.1 - 3.2e-20 72.3 0.0 5.6e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30997.1 - 7.1e-13 48.2 0.0 1.2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EPE30998.1 - 4e-20 72.0 0.1 7.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE30998.1 - 5.7e-11 41.9 0.0 6.3e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase HTH_25 PF13413.1 EPE31000.1 - 0.019 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Avl9 PF09794.4 EPE31001.1 - 4.6e-145 482.8 0.0 6.1e-145 482.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 EPE31001.1 - 3e-07 30.0 0.7 2.7e-06 26.8 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EPE31001.1 - 3.3e-07 29.9 0.0 0.00018 21.1 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis GST_N PF02798.15 EPE31002.1 - 7.7e-12 45.2 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPE31002.1 - 2.5e-11 43.6 0.0 5.2e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPE31002.1 - 3.7e-10 39.6 0.1 5.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPE31002.1 - 8.7e-10 38.4 0.0 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE31002.1 - 1.6e-05 24.6 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPE31002.1 - 1.8e-05 25.1 0.2 2.5e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2034 PF10356.4 EPE31003.1 - 7.6e-31 106.7 0.0 1.8e-15 56.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EPE31003.1 - 1.7e-08 34.2 0.0 2.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.3 EPE31004.1 - 2.6e-48 163.6 8.9 2.8e-48 163.5 6.2 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.1 EPE31004.1 - 0.0077 15.4 9.3 0.18 11.0 4.2 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.15 EPE31004.1 - 0.0084 15.2 7.5 0.0084 15.2 5.2 1.4 2 0 0 2 2 2 1 Tropomyosin Med9 PF07544.8 EPE31004.1 - 0.016 14.9 1.5 0.016 14.9 1.0 3.0 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Herpes_UL6 PF01763.11 EPE31004.1 - 0.034 12.3 1.9 0.034 12.3 1.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like AAA_23 PF13476.1 EPE31004.1 - 0.14 12.5 7.4 0.14 12.4 5.1 1.2 1 0 0 1 1 1 0 AAA domain SRP_SPB PF02978.14 EPE31004.1 - 0.18 12.0 1.5 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 Signal peptide binding domain DUF4642 PF15484.1 EPE31004.1 - 0.36 10.8 3.9 0.32 10.9 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4642) ADIP PF11559.3 EPE31004.1 - 0.59 10.0 9.8 0.37 10.6 4.4 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 EPE31004.1 - 0.63 10.1 5.1 2.6 8.1 3.3 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spore_III_AB PF09548.5 EPE31004.1 - 0.87 9.3 5.8 0.5 10.1 2.8 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF607 PF04678.8 EPE31004.1 - 0.98 9.3 4.5 1.4 8.8 3.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF607 CENP-Q PF13094.1 EPE31004.1 - 1.1 9.2 11.6 1.8 8.5 7.8 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 EPE31004.1 - 2.1 8.2 14.9 1.8 8.4 9.3 1.7 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.14 EPE31004.1 - 2.4 5.9 4.9 2.5 5.8 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EPE31004.1 - 2.8 6.9 12.1 3.6 6.5 8.4 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF948 PF06103.6 EPE31004.1 - 2.9 7.8 5.0 3.1 7.7 0.4 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF349 PF03993.7 EPE31004.1 - 4.5 7.5 9.6 6.7 6.9 3.8 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) IncA PF04156.9 EPE31004.1 - 6.7 6.2 14.9 2.1 7.9 7.9 1.7 1 1 1 2 2 2 0 IncA protein HAD_2 PF13419.1 EPE31005.1 - 3.8e-34 118.4 0.6 4.8e-34 118.1 0.4 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE31005.1 - 1.8e-06 27.5 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EPE31005.1 - 1.2e-05 25.8 0.0 3.2e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EPE31005.1 - 0.011 15.3 0.1 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase Pkinase PF00069.20 EPE31007.1 - 2.2e-71 240.0 0.0 2.8e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE31007.1 - 1.5e-31 109.4 0.0 1.8e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPE31007.1 - 2e-05 23.7 0.0 7.4e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE31007.1 - 0.00038 20.2 0.0 0.00089 19.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPE31007.1 - 0.00063 18.7 0.0 0.022 13.7 0.0 2.2 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EPE31007.1 - 0.025 13.9 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Polysacc_lyase PF14099.1 EPE31009.1 - 9.6e-05 22.1 2.2 0.00019 21.1 1.5 1.4 1 1 0 1 1 1 1 Polysaccharide lyase HIT PF01230.18 EPE31010.1 - 4.1e-22 78.5 0.1 5.9e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPE31010.1 - 2e-08 34.4 0.0 3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Mg_trans_NIPA PF05653.9 EPE31011.1 - 1.6e-91 306.4 27.4 2.2e-91 305.9 19.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EPE31011.1 - 8e-06 25.9 7.6 8e-06 25.9 5.3 3.0 3 1 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EPE31011.1 - 1.9e-05 24.8 5.3 1.9e-05 24.8 3.7 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Mpv17_PMP22 PF04117.7 EPE31012.1 - 6.1e-19 67.4 1.7 9.4e-19 66.8 0.1 2.0 1 1 1 2 2 2 1 Mpv17 / PMP22 family zf-RING_2 PF13639.1 EPE31013.1 - 2.3e-08 33.7 6.4 4.4e-08 32.8 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPE31013.1 - 2.2e-07 30.8 1.5 5e-07 29.7 1.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EPE31013.1 - 2.1e-06 27.5 4.4 4.8e-06 26.4 3.0 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EPE31013.1 - 9e-06 25.4 1.1 2e-05 24.3 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EPE31013.1 - 0.003 17.5 6.5 0.0062 16.5 4.5 1.6 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.17 EPE31013.1 - 0.0067 16.1 2.2 0.0067 16.1 1.6 1.8 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 EPE31013.1 - 0.0098 15.5 7.4 0.019 14.6 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE31013.1 - 0.049 13.3 4.3 0.091 12.4 3.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE31013.1 - 0.051 13.5 7.4 0.1 12.6 5.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EPE31013.1 - 0.098 12.6 6.0 0.21 11.5 4.2 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_5 PF14634.1 EPE31013.1 - 0.63 9.8 7.0 1.3 8.7 4.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 EPE31013.1 - 1.1 8.8 5.7 38 3.9 4.0 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EPE31013.1 - 3.3 7.4 5.8 6.1 6.6 4.0 1.5 1 0 0 1 1 1 0 PHD-finger BUD22 PF09073.5 EPE31015.1 - 0.5 9.3 27.5 0.97 8.4 19.1 1.6 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.20 EPE31017.1 - 4.1e-39 134.3 0.0 6.8e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE31017.1 - 1.1e-24 86.9 0.0 1.7e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Epimerase PF01370.16 EPE31019.1 - 1.1e-15 57.6 0.0 2e-15 56.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE31019.1 - 1.6e-11 43.4 0.0 4.1e-11 42.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPE31019.1 - 2.4e-08 33.2 0.2 2.2e-07 30.0 0.1 2.3 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.8 EPE31019.1 - 8.2e-08 31.7 0.1 1.2e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE31019.1 - 3.5e-07 30.3 0.9 6e-07 29.6 0.6 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPE31019.1 - 0.00041 19.3 0.1 0.00059 18.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPE31019.1 - 0.023 14.5 1.5 0.13 12.1 1.1 2.2 1 1 0 1 1 1 0 short chain dehydrogenase Na_Ca_ex PF01699.19 EPE31020.1 - 4.2e-28 97.7 16.7 5.5e-15 55.1 4.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Otopetrin PF03189.8 EPE31020.1 - 0.031 13.2 6.4 0.011 14.7 1.9 1.9 2 0 0 2 2 2 0 Otopetrin Cation_efflux PF01545.16 EPE31020.1 - 3.2 6.7 15.6 0.052 12.6 4.3 2.2 2 1 0 2 2 2 0 Cation efflux family DEAD PF00270.24 EPE31026.1 - 7.7e-26 90.5 0.0 1.6e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 EPE31026.1 - 1.7e-13 50.9 0.2 5.8e-13 49.2 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 EPE31026.1 - 3.7e-10 39.5 0.4 1.1e-09 38.0 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.6 EPE31026.1 - 0.00091 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like Rab_eff_C PF04698.7 EPE31026.1 - 0.56 8.2 2.1 0.42 8.6 0.1 1.6 2 0 0 2 2 2 0 Rab effector MyRIP/melanophilin C-terminus Inhibitor_I10 PF12559.3 EPE31028.1 - 0.073 13.3 0.8 0.13 12.5 0.5 1.5 1 1 0 1 1 1 0 Serine endopeptidase inhibitors QCR10 PF09796.4 EPE31029.1 - 1.2e-28 98.5 0.5 1.6e-28 98.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) U-box PF04564.10 EPE31030.1 - 6e-23 80.5 0.0 1.2e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EPE31030.1 - 1.8e-19 69.1 4.6 2.9e-13 49.2 0.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EPE31030.1 - 3.9e-08 32.5 3.9 0.0012 18.4 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPE31030.1 - 3e-07 29.8 4.8 0.0038 17.0 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPE31030.1 - 1.9e-06 27.5 1.3 0.058 13.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPE31030.1 - 2.7e-05 24.4 0.4 0.21 11.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPE31030.1 - 0.00012 22.3 0.5 1.1 10.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE31030.1 - 0.00058 20.4 0.7 0.036 14.7 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPE31030.1 - 0.02 14.8 6.0 0.69 9.8 1.8 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-Nse PF11789.3 EPE31030.1 - 0.03 13.8 0.0 0.11 12.0 0.0 1.9 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit HTH_Tnp_Mu_1 PF02316.11 EPE31030.1 - 0.062 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Mu DNA-binding domain Apc3 PF12895.2 EPE31030.1 - 0.076 13.1 1.0 0.17 12.0 0.7 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EPE31030.1 - 1.7 9.2 7.2 10 6.8 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat DIE2_ALG10 PF04922.7 EPE31031.1 - 7.8e-81 272.0 15.9 1.5e-58 198.6 0.6 2.2 2 0 0 2 2 2 2 DIE2/ALG10 family Sld5 PF05916.6 EPE31032.1 - 1.4e-25 89.6 0.0 2.3e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Flu_M1_C PF08289.6 EPE31032.1 - 0.026 14.5 0.2 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Peroxin-3 PF04882.7 EPE31033.1 - 0.011 14.4 0.2 0.016 13.9 0.1 1.3 1 0 0 1 1 1 0 Peroxin-3 NMO PF03060.10 EPE31034.1 - 1.6e-71 241.1 2.1 1.9e-71 240.8 1.4 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EPE31034.1 - 1.4e-08 34.0 0.6 3e-08 32.9 0.4 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EPE31034.1 - 8.7e-08 31.3 2.4 1.5e-07 30.6 1.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EPE31034.1 - 0.0038 16.2 0.3 0.0056 15.6 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EPE31034.1 - 0.0068 15.3 0.8 0.012 14.5 0.5 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Pterin_bind PF00809.17 EPE31035.1 - 9.1e-62 208.1 0.0 2e-61 207.0 0.0 1.6 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 EPE31035.1 - 2.8e-41 140.2 0.0 4.6e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Mit_KHE1 PF10173.4 EPE31035.1 - 0.032 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related HET PF06985.6 EPE31036.1 - 1.1e-28 100.1 0.2 2.3e-28 99.0 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EPE31037.1 - 3.3e-15 56.4 0.1 5.9e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Carla_C4 PF01623.12 EPE31038.1 - 0.37 10.5 3.9 0.17 11.6 0.8 1.8 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein Aspzincin_M35 PF14521.1 EPE31040.1 - 0.00035 21.1 0.0 0.00065 20.2 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase PRK PF00485.13 EPE31040.1 - 0.076 12.5 0.1 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family R3H PF01424.17 EPE31041.1 - 2.7e-12 46.1 0.0 6.1e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EPE31041.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE31041.1 - 2.2e-05 23.9 0.0 4.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE31041.1 - 0.00083 19.1 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 EPE31041.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Histone PF00125.19 EPE31042.1 - 4.6e-22 77.9 0.0 5.9e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPE31042.1 - 5e-05 23.2 0.0 7.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Fungal_trans PF04082.13 EPE31043.1 - 6e-09 35.1 0.3 1.4e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE31043.1 - 3.1e-07 30.1 10.3 5.4e-07 29.4 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 EPE31044.1 - 2.4e-34 118.9 0.0 2.9e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE31044.1 - 9e-08 31.6 0.2 2.9e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EPE31044.1 - 2.1e-07 30.6 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EPE31044.1 - 0.00062 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EPE31044.1 - 0.0011 17.8 0.0 0.07 12.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein TrkA_N PF02254.13 EPE31044.1 - 0.029 14.3 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Semialdhyde_dh PF01118.19 EPE31044.1 - 0.033 14.5 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EPE31044.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain AAA PF00004.24 EPE31046.1 - 5.4e-12 46.0 0.0 1.3e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE31046.1 - 2.2e-06 27.8 0.0 5.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPE31046.1 - 6.3e-06 25.9 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPE31046.1 - 2.5e-05 23.9 0.3 0.00022 20.9 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 EPE31046.1 - 3.7e-05 22.8 0.0 6.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EPE31046.1 - 0.00024 19.9 0.0 0.00046 19.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EPE31046.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE31046.1 - 0.0021 18.8 0.1 0.012 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPE31046.1 - 0.0025 17.6 0.1 0.0081 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPE31046.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 EPE31046.1 - 0.014 15.1 1.0 0.14 11.8 0.1 2.5 1 1 1 2 2 2 0 NTPase AAA_16 PF13191.1 EPE31046.1 - 0.018 15.0 0.1 0.095 12.6 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain TIP49 PF06068.8 EPE31046.1 - 0.04 12.6 0.0 0.074 11.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 EPE31046.1 - 0.045 13.1 0.3 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 EPE31046.1 - 0.058 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EPE31046.1 - 0.074 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EPE31046.1 - 0.096 12.9 0.4 0.46 10.7 0.1 2.2 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 EPE31046.1 - 0.16 11.5 0.0 0.78 9.3 0.0 2.1 1 1 0 1 1 1 0 NACHT domain Fungal_trans PF04082.13 EPE31047.1 - 3.7e-23 81.7 2.6 4.7e-23 81.3 1.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_2 PF13639.1 EPE31048.1 - 3.7e-16 58.6 17.8 9.5e-16 57.3 4.4 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 EPE31048.1 - 4e-12 45.6 7.2 8.7e-10 38.1 0.9 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE31048.1 - 6.9e-08 32.3 15.2 3.9e-07 29.9 4.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE31048.1 - 1.1e-06 28.2 3.3 1.1e-06 28.2 2.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EPE31048.1 - 1.5e-06 28.2 2.0 1.5e-06 28.2 1.4 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPE31048.1 - 5.4e-06 25.9 13.0 0.0002 20.9 3.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 EPE31048.1 - 0.0019 17.8 0.4 0.0019 17.8 0.3 2.1 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-Apc11 PF12861.2 EPE31048.1 - 0.0053 16.5 1.5 0.0053 16.5 1.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 EPE31048.1 - 0.011 15.6 6.9 0.15 12.0 2.9 2.6 2 0 0 2 2 2 0 zinc-finger Baculo_RING PF05883.6 EPE31048.1 - 0.22 11.3 1.8 0.51 10.1 0.1 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain PHD PF00628.24 EPE31048.1 - 0.25 11.0 16.0 0.023 14.3 3.7 2.6 2 1 0 2 2 2 0 PHD-finger Prok-RING_4 PF14447.1 EPE31048.1 - 0.86 9.1 7.9 0.076 12.5 1.8 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 EPE31048.1 - 1.2 9.0 7.7 1.1 9.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.7 EPE31048.1 - 1.4 8.8 5.2 1.8 8.3 0.3 2.8 3 0 0 3 3 3 0 zinc-ribbons NADH-G_4Fe-4S_3 PF10588.4 EPE31048.1 - 1.6 8.0 6.2 1.8 7.8 0.0 2.7 3 0 0 3 3 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C3HC4_4 PF15227.1 EPE31048.1 - 2.9 7.8 13.6 2.7 7.9 1.1 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPE31048.1 - 3.3 7.3 11.8 2.1 7.9 1.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RecR PF02132.10 EPE31048.1 - 4.4 6.8 6.5 13 5.3 0.0 3.1 3 0 0 3 3 3 0 RecR protein Prok-RING_1 PF14446.1 EPE31048.1 - 5.4 6.8 14.1 8.1 6.2 3.2 3.2 2 2 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.2 EPE31048.1 - 6.4 6.6 7.8 0.93 9.3 0.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon Fis1_TPR_C PF14853.1 EPE31049.1 - 5.5e-25 86.9 0.5 9.7e-25 86.2 0.4 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EPE31049.1 - 2.6e-17 61.8 0.1 5.9e-17 60.6 0.0 1.7 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EPE31049.1 - 0.011 15.5 0.9 0.021 14.6 0.7 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPE31049.1 - 0.012 16.2 0.1 0.022 15.4 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.6 EPE31050.1 - 3.6e-28 97.6 0.3 1.4e-26 92.4 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF4613 PF15390.1 EPE31050.1 - 0.022 12.9 1.4 0.026 12.7 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Reo_sigmaC PF04582.7 EPE31050.1 - 0.032 13.4 3.6 0.042 13.0 2.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Prefoldin_2 PF01920.15 EPE31050.1 - 0.064 13.0 2.4 0.4 10.4 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Ax_dynein_light PF10211.4 EPE31050.1 - 0.086 12.6 2.1 0.14 11.9 0.6 1.8 1 1 1 2 2 2 0 Axonemal dynein light chain YscO PF07321.7 EPE31050.1 - 0.13 12.1 2.3 0.18 11.6 1.6 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO APG6 PF04111.7 EPE31050.1 - 0.13 11.2 4.3 0.17 10.9 3.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.9 EPE31050.1 - 0.26 10.9 1.8 1.8 8.1 1.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FlxA PF14282.1 EPE31050.1 - 0.58 10.1 5.5 1.5 8.8 2.6 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF4164 PF13747.1 EPE31050.1 - 0.61 10.2 10.8 3.9 7.6 5.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) IncA PF04156.9 EPE31050.1 - 1.4 8.4 9.4 5.1 6.6 0.7 2.0 1 1 1 2 2 2 0 IncA protein TBPIP PF07106.8 EPE31050.1 - 1.7 8.1 4.3 7.1 6.1 0.8 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 EPE31050.1 - 4 7.3 8.4 1 9.2 1.1 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EPE31050.1 - 5.2 6.9 10.3 4.8 7.0 0.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DASH_Hsk3 PF08227.6 EPE31050.1 - 7.9 6.7 9.9 0.83 9.8 0.8 2.4 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF566 PF04484.7 EPE31051.1 - 1.2 8.5 4.2 2.9 7.3 2.9 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF566) TatD_DNase PF01026.16 EPE31052.1 - 8.7e-31 107.0 0.0 1.4e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase Myb_DNA-bind_6 PF13921.1 EPE31053.1 - 0.075 13.1 0.0 0.95 9.6 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain SNF2_N PF00176.18 EPE31054.1 - 1.4e-66 224.3 0.3 1.4e-66 224.3 0.2 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE31054.1 - 1.1e-15 57.2 0.0 4.9e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE31054.1 - 3.3e-06 27.0 0.0 3.3e-06 27.0 0.0 3.6 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EPE31054.1 - 0.00011 21.1 0.0 0.00011 21.1 0.0 2.1 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 SecG PF03840.9 EPE31055.1 - 0.13 12.0 0.3 0.22 11.3 0.2 1.3 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Herpes_UL16 PF03044.9 EPE31055.1 - 0.14 11.1 0.3 3.4 6.5 0.0 2.0 1 1 1 2 2 2 0 Herpesvirus UL16/UL94 family Coq4 PF05019.8 EPE31056.1 - 0.0049 15.8 0.5 0.77 8.6 0.0 2.0 1 1 1 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF4443 PF14544.1 EPE31056.1 - 0.032 14.1 4.4 0.81 9.6 0.3 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4443) gpUL132 PF11359.3 EPE31057.1 - 0.017 14.4 4.3 0.03 13.6 3.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Rifin_STEVOR PF02009.11 EPE31058.1 - 0.00041 20.0 0.0 0.0006 19.5 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family GAPT PF11770.3 EPE31058.1 - 0.046 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) DUF2029 PF09594.5 EPE31058.1 - 0.048 13.1 0.1 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) Adeno_E3_CR2 PF02439.10 EPE31058.1 - 0.13 11.8 0.3 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 EPE31058.1 - 0.13 11.5 0.2 0.33 10.3 0.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TBPIP PF07106.8 EPE31059.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WSC PF01822.14 EPE31060.1 - 2.9e-43 145.6 74.5 1.3e-10 41.0 3.0 6.2 6 0 0 6 6 6 5 WSC domain LCM PF04072.9 EPE31060.1 - 1.6e-19 70.2 0.0 2.6e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase SUN PF03856.8 EPE31061.1 - 7.3e-76 254.7 15.9 1.2e-75 254.1 11.0 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF2217 PF10265.4 EPE31061.1 - 0.28 9.9 14.3 0.42 9.3 9.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4551 PF15087.1 EPE31061.1 - 9.4 4.4 13.5 17 3.6 9.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Reo_sigmaC PF04582.7 EPE31062.1 - 0.028 13.6 17.9 0.04 13.0 1.3 3.4 2 2 1 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EPE31062.1 - 0.04 14.1 29.1 0.5 10.6 0.0 8.2 6 2 2 9 9 9 0 Nucleopolyhedrovirus P10 protein DASH_Dad3 PF08656.5 EPE31062.1 - 2 8.1 10.7 4.1 7.1 0.4 5.0 3 1 1 4 4 4 0 DASH complex subunit Dad3 DUF812 PF05667.6 EPE31063.1 - 0.017 13.6 22.2 0.045 12.2 15.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Sigma54_activ_2 PF14532.1 EPE31063.1 - 0.04 13.9 0.5 0.24 11.4 0.3 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Peptidase_S64 PF08192.6 EPE31064.1 - 0.66 8.2 10.4 0.51 8.6 6.2 1.4 1 1 0 1 1 1 0 Peptidase family S64 CPSF73-100_C PF11718.3 EPE31064.1 - 5.3 6.3 7.0 0.58 9.4 0.3 2.3 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term AT_hook PF02178.14 EPE31065.1 - 0.027 14.1 5.1 0.094 12.4 3.5 2.0 1 0 0 1 1 1 0 AT hook motif Ion_trans_2 PF07885.11 EPE31066.1 - 4.1e-28 96.9 24.1 7.1e-17 60.8 2.7 3.0 3 0 0 3 3 3 2 Ion channel DUF3456 PF11938.3 EPE31066.1 - 0.015 15.2 0.1 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Claudin_2 PF13903.1 EPE31066.1 - 2.2 7.9 12.6 0.6 9.7 4.8 2.8 2 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction SKN1 PF03935.10 EPE31067.1 - 3.5e-222 738.0 0.3 4.1e-222 737.7 0.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF3716 PF12511.3 EPE31068.1 - 1.4e-13 50.2 5.6 2.2e-13 49.6 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Mit_KHE1 PF10173.4 EPE31069.1 - 4.8e-64 215.6 0.0 7.6e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related MARVEL PF01284.18 EPE31070.1 - 0.0089 15.8 0.6 0.015 15.1 0.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.7 EPE31070.1 - 0.017 14.6 0.1 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Cupin_2 PF07883.6 EPE31071.1 - 4.8e-06 25.9 0.2 8.3e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EPE31071.1 - 6.2e-05 22.4 0.1 8.8e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EPE31071.1 - 0.00014 21.5 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 EPE31071.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cullin PF00888.17 EPE31072.1 - 5.3e-201 669.1 13.6 7e-201 668.7 9.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EPE31072.1 - 2.3e-26 91.3 7.0 2.5e-26 91.2 2.7 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Erf4 PF10256.4 EPE31072.1 - 0.058 13.2 1.6 1.2 9.0 0.2 2.7 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family G-alpha PF00503.15 EPE31074.1 - 9.1e-124 413.0 0.1 1.1e-123 412.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EPE31074.1 - 1.7e-15 56.7 0.9 2.6e-10 39.8 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPE31074.1 - 0.00053 19.1 0.4 0.48 9.5 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EPE31074.1 - 0.0011 19.4 0.0 0.35 11.3 0.0 2.7 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 EPE31074.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.15 EPE31075.1 - 0 1073.1 0.4 0 1072.5 0.2 1.3 1 0 0 1 1 1 1 Carbohydrate phosphorylase GATA PF00320.22 EPE31076.1 - 2.3e-14 52.4 2.4 5.1e-14 51.3 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger DegS PF05384.6 EPE31076.1 - 0.0076 15.4 5.4 0.015 14.4 3.8 1.6 1 1 0 1 1 1 1 Sensor protein DegS Tropomyosin PF00261.15 EPE31076.1 - 0.037 13.1 11.3 0.049 12.7 7.8 1.1 1 0 0 1 1 1 0 Tropomyosin DivIVA PF05103.8 EPE31076.1 - 0.081 12.9 6.2 0.12 12.3 4.3 1.3 1 0 0 1 1 1 0 DivIVA protein ADIP PF11559.3 EPE31076.1 - 0.46 10.3 11.3 2 8.3 5.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 EPE31076.1 - 0.56 9.0 8.7 1.1 8.1 6.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fmp27_WPPW PF10359.4 EPE31076.1 - 1.1 7.6 5.3 1.5 7.1 3.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain KH_3 PF13014.1 EPE31077.1 - 0.045 13.4 0.0 0.82 9.3 0.0 2.7 3 0 0 3 3 3 0 KH domain Fungal_trans PF04082.13 EPE31078.1 - 1.7e-06 27.1 0.0 2.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE31078.1 - 0.063 13.2 1.0 0.13 12.1 0.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain KH_3 PF13014.1 EPE31079.1 - 5.3e-27 92.9 6.0 8.1e-06 25.3 0.0 6.5 6 0 0 6 6 6 5 KH domain KH_1 PF00013.24 EPE31079.1 - 1.4e-26 91.8 6.9 1.5e-07 30.9 0.3 7.6 8 0 0 8 8 8 6 KH domain Myb_DNA-binding PF00249.26 EPE31081.1 - 0.0058 16.6 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ResIII PF04851.10 EPE31082.1 - 1.2e-24 87.1 0.0 3.4e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPE31082.1 - 3.1e-14 52.5 0.0 8.7e-14 51.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPE31082.1 - 1.1e-12 47.7 0.0 2.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 EPE31082.1 - 0.00017 20.9 1.5 0.066 12.4 0.0 3.1 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EPE31082.1 - 0.00064 18.8 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 EPE31082.1 - 0.067 11.9 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 EPE31082.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain SWIRM PF04433.12 EPE31084.1 - 1.6e-34 117.8 0.1 2.8e-34 117.0 0.1 1.4 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 EPE31084.1 - 1.8e-06 27.9 0.0 4.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3439 PF11921.3 EPE31084.1 - 0.2 11.3 6.5 0.46 10.2 4.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ZZ PF00569.12 EPE31084.1 - 0.77 9.3 7.3 5.9 6.5 5.1 2.2 1 1 0 1 1 1 0 Zinc finger, ZZ type ETF PF01012.16 EPE31085.1 - 8e-38 129.7 1.8 8.1e-38 129.7 0.4 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EPE31085.1 - 2e-34 117.0 0.2 4.1e-34 116.0 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Pyr_redox_2 PF07992.9 EPE31086.1 - 0.00011 22.1 0.0 0.0011 18.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE31086.1 - 0.00034 20.7 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MutL_C PF08676.6 EPE31088.1 - 2.4e-23 82.3 0.0 6.8e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EPE31088.1 - 9.5e-19 67.0 0.0 3.2e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EPE31088.1 - 1.4e-14 53.8 0.0 4.4e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EPE31088.1 - 2.5e-11 43.2 0.0 5.3e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cys_Met_Meta_PP PF01053.15 EPE31089.1 - 4.5e-137 456.4 0.0 5.3e-137 456.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPE31089.1 - 1.4e-06 27.5 0.0 2.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPE31089.1 - 2.2e-05 23.3 0.0 5.5e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPE31089.1 - 7.5e-05 21.9 0.1 0.00023 20.3 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 EPE31089.1 - 0.00013 20.4 0.1 0.00051 18.4 0.1 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 EPE31089.1 - 0.00068 18.8 0.0 0.0027 16.9 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EPE31089.1 - 0.0038 15.9 0.0 0.0089 14.7 0.0 1.5 2 0 0 2 2 2 1 Glycine cleavage system P-protein POTRA_2 PF08479.6 EPE31089.1 - 0.0075 15.9 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 POTRA domain, ShlB-type RE_XamI PF09572.5 EPE31090.1 - 0.17 11.2 0.6 0.27 10.6 0.4 1.2 1 0 0 1 1 1 0 XamI restriction endonuclease AIG2 PF06094.7 EPE31091.1 - 5.6e-08 33.1 0.0 9.5e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 EPE31091.1 - 9.9e-05 22.3 0.0 0.005 16.9 0.0 2.3 2 0 0 2 2 2 1 AIG2-like family HSP20 PF00011.16 EPE31092.1 - 2.4e-13 49.8 0.0 2.7e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Med3 PF11593.3 EPE31092.1 - 0.29 10.3 3.6 0.08 12.1 0.5 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal SH3_9 PF14604.1 EPE31093.1 - 1.5e-10 40.4 0.0 2.3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPE31093.1 - 2.1e-07 30.1 0.0 3.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPE31093.1 - 2.1e-06 27.0 0.0 4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TMEM154 PF15102.1 EPE31093.1 - 0.025 14.2 3.4 0.14 11.8 2.4 2.2 1 1 0 1 1 1 0 TMEM154 protein family DUF2668 PF10873.3 EPE31093.1 - 0.034 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) EphA2_TM PF14575.1 EPE31093.1 - 0.054 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EPE31093.1 - 0.069 11.4 0.0 0.14 10.4 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Rifin_STEVOR PF02009.11 EPE31093.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family Amnionless PF14828.1 EPE31093.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless Podoplanin PF05808.6 EPE31093.1 - 4.2 6.9 18.3 0.1 12.1 6.0 2.4 2 1 1 3 3 3 0 Podoplanin ATG22 PF11700.3 EPE31095.1 - 3.4e-182 606.2 26.0 3.8e-182 606.0 18.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EPE31095.1 - 6.5e-05 21.7 47.8 0.0089 14.7 4.5 3.5 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 EPE31095.1 - 0.11 12.3 6.5 3.1 7.6 0.0 3.7 4 0 0 4 4 4 0 MFS_1 like family DUF2809 PF10990.3 EPE31095.1 - 0.2 12.1 0.1 0.2 12.1 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2809) DUF3425 PF11905.3 EPE31096.1 - 5.7e-29 100.7 0.1 1e-28 99.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) RTA1 PF04479.8 EPE31097.1 - 7.4e-46 156.4 7.8 1.2e-45 155.7 5.4 1.3 1 0 0 1 1 1 1 RTA1 like protein Syndecan PF01034.15 EPE31097.1 - 2.7 7.7 7.6 6.2 6.5 0.0 3.4 4 0 0 4 4 4 0 Syndecan domain Glyco_hydro_61 PF03443.9 EPE31098.1 - 3.2e-81 272.3 0.0 4.1e-81 271.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Lipase_GDSL PF00657.17 EPE31101.1 - 2.2e-17 63.6 0.8 2.8e-17 63.3 0.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FAD_binding_3 PF01494.14 EPE31102.1 - 4.1e-46 157.6 0.0 5.8e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE31102.1 - 1.6e-07 30.5 0.0 0.0022 16.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE31102.1 - 1e-05 24.6 0.3 7.2e-05 21.8 0.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPE31102.1 - 2.2e-05 23.4 0.1 0.0035 16.2 0.5 2.1 1 1 1 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EPE31102.1 - 2.3e-05 23.0 0.4 0.0004 18.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EPE31102.1 - 2.9e-05 23.9 1.1 0.00011 22.1 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPE31102.1 - 6.1e-05 22.2 0.1 0.00011 21.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EPE31102.1 - 0.00013 21.2 0.0 0.00018 20.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPE31102.1 - 0.0012 19.1 0.1 0.1 13.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EPE31102.1 - 0.0051 15.9 0.5 0.035 13.1 0.0 2.3 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EPE31102.1 - 0.011 15.8 0.2 0.071 13.1 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE31102.1 - 0.022 14.5 0.4 4.3 7.0 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPE31102.1 - 0.031 14.1 0.7 0.14 11.9 0.5 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPE31102.1 - 0.036 12.9 0.1 0.054 12.3 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EPE31102.1 - 0.091 11.3 0.3 3 6.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 EPE31102.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EPE31102.1 - 0.14 11.5 0.2 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 EPE31103.1 - 1.1e-15 57.9 0.0 1.5e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE31103.1 - 1.1e-10 41.5 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE31103.1 - 2.7e-07 30.6 0.0 3.4e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPE31103.1 - 0.00042 19.8 0.0 0.00067 19.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-C2HC_2 PF13913.1 EPE31104.1 - 9.6e-05 21.9 1.9 0.00022 20.7 1.3 1.7 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 EPE31104.1 - 0.41 11.1 8.8 0.34 11.3 0.4 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE31105.1 - 0.27 11.5 0.3 0.27 11.5 0.2 2.3 3 0 0 3 3 3 0 Zinc-finger double domain Cupin_8 PF13621.1 EPE31110.1 - 2.7e-42 145.0 0.0 4.5e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EPE31110.1 - 2.6e-08 33.5 0.0 1.4e-06 27.8 0.0 2.5 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EPE31110.1 - 0.038 14.2 0.0 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.6 EPE31110.1 - 0.088 12.3 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Reticulon PF02453.12 EPE31111.1 - 1.6e-39 135.1 6.3 2.5e-39 134.6 4.3 1.3 1 0 0 1 1 1 1 Reticulon DUF883 PF05957.8 EPE31111.1 - 0.039 14.3 2.3 0.18 12.2 0.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2547 PF10818.3 EPE31111.1 - 0.041 14.4 4.6 0.15 12.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2547) SieB PF14163.1 EPE31111.1 - 0.058 12.9 0.1 1.2 8.7 0.1 2.4 1 1 1 2 2 2 0 Superinfection exclusion protein B ApoO PF09769.4 EPE31111.1 - 0.84 9.3 4.5 0.22 11.2 0.1 2.2 2 1 0 2 2 2 0 Apolipoprotein O FUSC_2 PF13515.1 EPE31111.1 - 1.1 9.2 8.3 6.1 6.7 0.8 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein-like DUF21 PF01595.15 EPE31111.1 - 1.4 8.1 7.7 1.3 8.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF21 COesterase PF00135.23 EPE31114.1 - 1.1e-97 328.0 0.0 1.4e-97 327.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE31114.1 - 0.0012 18.4 0.0 0.0063 16.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold GST_N_3 PF13417.1 EPE31116.1 - 5.2e-17 61.8 0.1 1e-16 60.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPE31116.1 - 6.7e-13 48.4 0.0 1.2e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPE31116.1 - 2.1e-06 27.7 0.0 4.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE31116.1 - 0.00057 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EPE31116.1 - 0.0093 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.1 EPE31116.1 - 0.042 14.3 0.0 0.06 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Rpn3_C PF08375.6 EPE31116.1 - 0.11 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal Hepsin-SRCR PF09272.5 EPE31117.1 - 0.063 13.5 0.3 0.091 12.9 0.2 1.3 1 0 0 1 1 1 0 Hepsin, SRCR HET PF06985.6 EPE31118.1 - 1e-28 100.2 0.1 2e-28 99.2 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EPE31119.1 - 1.8e-30 105.8 0.1 3e-30 105.2 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GTP1_OBG PF01018.17 EPE31120.1 - 3.7e-36 124.1 2.6 2e-27 95.7 1.7 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EPE31120.1 - 9.6e-22 77.1 0.0 1.8e-21 76.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE31120.1 - 3.7e-07 29.5 0.0 8.3e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EPE31120.1 - 0.012 15.0 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EPE31120.1 - 0.03 14.2 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EPE31120.1 - 0.048 12.4 0.0 0.22 10.2 0.0 1.9 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 EPE31120.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 EPE31120.1 - 0.1 12.9 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EPE31120.1 - 0.14 11.9 0.1 2.9 7.6 0.0 2.5 1 1 0 1 1 1 0 Dynamin family Arf PF00025.16 EPE31120.1 - 0.19 10.9 0.0 0.51 9.5 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF4413 PF14372.1 EPE31122.1 - 0.5 10.3 3.1 7.9 6.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4413) Med9 PF07544.8 EPE31122.1 - 2.1 8.1 17.7 1.2 8.9 0.7 5.2 2 1 3 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 RNA_pol_Rpb5_C PF01191.14 EPE31123.1 - 8.3e-36 121.4 0.2 2e-35 120.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EPE31123.1 - 1.3e-26 92.8 0.0 2.1e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EPE31123.1 - 0.0043 16.8 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease MFS_1 PF07690.11 EPE31124.1 - 1.9e-36 125.5 33.4 1.9e-36 125.5 23.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE31124.1 - 8.9e-10 37.7 16.1 4.8e-07 28.7 9.6 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter AMP-binding PF00501.23 EPE31125.1 - 2.8e-84 282.9 0.2 3.4e-84 282.6 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE31125.1 - 8.7e-11 42.6 0.2 2.6e-10 41.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Nol1_Nop2_Fmu PF01189.12 EPE31126.1 - 1.7e-30 106.4 0.0 1.7e-19 70.2 0.0 4.1 4 1 0 4 4 4 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EPE31126.1 - 0.0045 17.0 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Aldolase_II PF00596.16 EPE31127.1 - 4.2e-46 156.8 0.1 5.5e-46 156.4 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain p450 PF00067.17 EPE31128.1 - 4.3e-33 114.5 0.0 5.7e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GM_CSF PF01109.12 EPE31130.1 - 0.013 15.3 0.1 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Cep57_CLD PF14073.1 EPE31130.1 - 0.049 13.4 12.2 0.097 12.4 8.5 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 CDC45 PF02724.9 EPE31132.1 - 4.7e-244 811.1 0.3 2.3e-243 808.8 0.2 2.5 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.7 EPE31132.1 - 0.00046 19.9 6.5 0.00046 19.9 4.5 2.3 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein HET PF06985.6 EPE31133.1 - 1.8e-28 99.4 0.1 6.8e-28 97.5 0.1 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CHAT PF12770.2 EPE31134.1 - 3.9e-33 114.8 0.0 5.2e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EPE31134.1 - 0.00021 20.8 0.1 0.03 13.9 0.3 2.9 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 EPE31134.1 - 0.018 15.0 0.5 0.57 10.1 0.0 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPE31134.1 - 0.26 11.2 1.6 11 6.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPE31135.1 - 1.2e-07 31.5 24.0 0.012 15.4 4.5 5.9 3 2 5 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EPE31135.1 - 1.8e-07 30.6 23.7 0.0062 16.1 3.7 6.1 2 2 5 8 8 8 4 TPR repeat Peptidase_C10 PF01640.12 EPE31135.1 - 0.005 16.6 1.7 0.68 9.6 0.0 3.4 3 1 0 4 4 4 1 Peptidase C10 family TPR_17 PF13431.1 EPE31135.1 - 0.006 16.6 14.3 6 7.3 0.1 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPE31135.1 - 4.2 7.3 6.5 8.1 6.4 0.4 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat adh_short PF00106.20 EPE31137.1 - 2.4e-08 34.0 0.0 4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE31137.1 - 3.2e-06 27.0 0.0 4.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE31137.1 - 5.1e-05 23.0 0.0 8.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 KR domain CCDC71L PF15374.1 EPE31137.1 - 0.17 11.1 0.2 0.22 10.8 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L MFS_1 PF07690.11 EPE31138.1 - 9.1e-33 113.4 30.0 9.1e-33 113.4 20.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2183 PF09949.4 EPE31138.1 - 8.2e-31 105.9 0.0 1.6e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Sugar_tr PF00083.19 EPE31138.1 - 3.9e-21 75.1 4.1 3.9e-21 75.1 2.9 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter Glyco_hydro_18 PF00704.23 EPE31140.1 - 6.8e-52 177.0 3.1 1e-51 176.4 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EPE31140.1 - 9.3e-10 38.2 0.2 0.0012 18.7 0.0 2.8 2 0 0 2 2 2 2 LysM domain DUF3142 PF11340.3 EPE31140.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) Chitin_bind_1 PF00187.14 EPE31140.1 - 0.0052 16.7 2.8 0.0052 16.7 1.9 3.0 2 0 0 2 2 2 1 Chitin recognition protein DnaJ PF00226.26 EPE31142.1 - 6.5e-21 73.8 1.1 1.6e-20 72.5 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain Fungal_trans_2 PF11951.3 EPE31143.1 - 1.3e-36 126.0 0.0 1.9e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE31143.1 - 1.5e-06 27.9 12.4 1.5e-06 27.9 8.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_gp2 PF05955.6 EPE31143.1 - 0.15 11.3 0.2 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 Equine herpesvirus glycoprotein gp2 Dioxygenase_C PF00775.16 EPE31144.1 - 1.1e-51 174.7 0.0 1.4e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EPE31144.1 - 1.5e-10 40.9 0.0 2.5e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EPE31144.1 - 0.00012 22.0 0.0 0.00094 19.1 0.0 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain FAD_binding_3 PF01494.14 EPE31145.1 - 1.1e-85 287.7 0.0 2.3e-85 286.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EPE31145.1 - 7.4e-53 178.6 0.0 1.3e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 EPE31145.1 - 1e-05 24.6 0.2 2e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EPE31145.1 - 2.5e-05 22.9 0.2 3.8e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EPE31145.1 - 4.1e-05 22.8 0.1 0.00033 19.8 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EPE31145.1 - 0.00011 22.2 0.3 0.00023 21.0 0.1 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPE31145.1 - 0.0011 17.8 0.2 0.0019 17.1 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EPE31145.1 - 0.0014 17.8 0.2 0.0024 17.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EPE31145.1 - 0.0028 16.6 0.0 0.0089 14.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE31145.1 - 0.0031 17.5 0.1 0.028 14.4 0.0 2.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE31145.1 - 0.015 14.2 0.1 0.029 13.2 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EPE31145.1 - 0.045 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 EPE31145.1 - 0.064 12.0 0.0 0.73 8.6 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.9 EPE31145.1 - 0.069 11.7 1.2 0.69 8.4 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EPE31145.1 - 0.095 12.7 0.1 0.3 11.1 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.2 EPE31146.1 - 2.1e-32 112.8 0.0 2.5e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE31146.1 - 6.4e-23 81.5 0.0 1.1e-16 61.1 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE31146.1 - 2.3e-21 76.0 0.4 8.2e-21 74.2 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE31146.1 - 7.1e-07 28.9 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EPE31146.1 - 2e-06 27.2 0.0 0.036 13.3 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family PGAP1 PF07819.8 EPE31146.1 - 3.6e-06 26.7 0.0 6.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 EPE31146.1 - 9.7e-05 21.8 0.0 1.8 7.9 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ndr PF03096.9 EPE31146.1 - 0.00025 19.6 0.0 0.00035 19.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.15 EPE31146.1 - 0.00031 21.0 0.0 0.00043 20.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 EPE31146.1 - 0.00052 19.6 0.0 0.00094 18.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF1057 PF06342.7 EPE31146.1 - 0.0016 17.3 0.0 0.0022 16.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.8 EPE31146.1 - 0.0017 17.9 0.1 0.0037 16.8 0.1 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 EPE31146.1 - 0.0026 16.1 0.0 0.086 11.1 0.0 2.1 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.9 EPE31146.1 - 0.0027 17.0 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) BAAT_C PF08840.6 EPE31146.1 - 0.0035 17.0 0.0 0.031 13.9 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.8 EPE31146.1 - 0.005 16.4 0.0 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase Pro_CA PF00484.14 EPE31146.1 - 0.0075 16.2 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Carbonic anhydrase AXE1 PF05448.7 EPE31146.1 - 0.01 14.3 0.2 0.021 13.3 0.2 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF915 PF06028.6 EPE31146.1 - 0.01 14.9 0.0 0.91 8.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.2 EPE31146.1 - 0.015 14.1 0.2 0.13 11.1 0.1 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme Acyl_transf_1 PF00698.16 EPE31146.1 - 0.021 14.1 0.3 0.031 13.6 0.2 1.2 1 0 0 1 1 1 0 Acyl transferase domain Abhydrolase_8 PF06259.7 EPE31146.1 - 0.024 14.1 0.6 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase DUF1598 PF07643.6 EPE31146.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) Esterase PF00756.15 EPE31146.1 - 0.038 13.3 0.6 0.078 12.3 0.1 1.7 1 1 1 2 2 2 0 Putative esterase UPF0227 PF05728.7 EPE31146.1 - 0.057 13.1 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.16 EPE31146.1 - 0.067 12.4 0.0 7 5.8 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2048 PF09752.4 EPE31146.1 - 0.098 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_9 PF10081.4 EPE31146.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family BRX_N PF13713.1 EPE31147.1 - 0.024 14.0 0.7 0.044 13.2 0.5 1.5 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Ank_2 PF12796.2 EPE31148.1 - 3.1e-59 197.3 2.8 4.1e-18 65.4 0.0 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EPE31148.1 - 8.1e-45 148.4 8.2 5.2e-07 29.1 0.0 11.1 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.1 EPE31148.1 - 3.9e-39 132.3 6.3 3.3e-09 37.0 0.1 8.6 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE31148.1 - 2.9e-36 119.8 5.4 0.00072 19.5 0.0 10.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 EPE31148.1 - 2.1e-34 116.7 3.4 5.9e-08 32.7 0.1 7.9 3 1 4 7 7 7 7 Ankyrin repeats (many copies) NACHT PF05729.7 EPE31148.1 - 4.1e-11 42.8 0.4 6.5e-10 38.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EPE31148.1 - 4.6e-05 23.4 1.3 8.4e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPE31148.1 - 0.0033 17.5 0.1 0.068 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain LBR_tudor PF09465.5 EPE31149.1 - 0.12 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Pyr_redox_3 PF13738.1 EPE31150.1 - 2.3e-23 83.3 0.0 5.6e-23 82.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE31150.1 - 1.4e-09 37.7 0.0 3.4e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EPE31150.1 - 5.5e-09 35.3 0.0 6.7e-07 28.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EPE31150.1 - 8e-07 27.6 0.0 5.9e-06 24.7 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EPE31150.1 - 2.6e-05 24.0 0.2 0.00014 21.7 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPE31150.1 - 0.00011 22.1 0.0 0.00043 20.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE31150.1 - 0.078 12.0 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EPE31150.1 - 0.08 11.3 0.1 0.15 10.4 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Peptidase_S10 PF00450.17 EPE31151.1 - 2e-104 350.0 0.0 2.5e-104 349.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EPE31151.1 - 0.031 14.1 0.0 0.23 11.2 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EPE31152.1 - 2.6e-09 36.3 0.0 3.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 EPE31152.1 - 4.8e-09 36.1 0.3 7.1e-09 35.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EPE31152.1 - 3.7e-06 25.9 0.0 5.4e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase PAF-AH_p_II PF03403.8 EPE31152.1 - 3.8e-05 22.1 0.0 0.012 13.9 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.8 EPE31152.1 - 0.051 13.1 0.1 0.083 12.4 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold HET PF06985.6 EPE31153.1 - 2.8e-17 63.1 0.0 6.7e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GBV-C_env PF12786.2 EPE31153.1 - 0.061 11.7 0.2 0.097 11.1 0.1 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope DUF934 PF06073.7 EPE31153.1 - 0.084 12.5 0.1 0.52 10.0 0.0 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF934) HET PF06985.6 EPE31154.1 - 4.2e-27 95.0 0.6 4.2e-27 95.0 0.4 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 EPE31155.1 - 3.3e-50 170.9 0.0 4.3e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DSPc PF00782.15 EPE31157.1 - 2.2e-14 53.1 0.2 5.1e-14 51.9 0.2 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EPE31157.1 - 0.012 14.5 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EPE31157.1 - 0.085 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MFS_1 PF07690.11 EPE31158.1 - 3.2e-12 45.8 32.0 5.7e-12 45.0 22.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EPE31158.1 - 1e-09 38.1 9.1 1e-09 38.1 6.3 3.9 4 1 1 5 5 5 1 Ion channel regulatory protein UNC-93 End3 PF12761.2 EPE31159.1 - 4.8e-72 241.7 0.7 6.5e-72 241.2 0.5 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EPE31159.1 - 1.4e-51 172.5 0.0 1.8e-49 165.7 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EPE31159.1 - 5.2e-08 31.6 0.8 3.8e-07 28.9 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EPE31159.1 - 7.5e-08 31.8 0.1 2.3e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EPE31159.1 - 9.6e-06 25.6 0.2 8.9e-05 22.5 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EPE31159.1 - 0.00027 20.5 1.3 0.0024 17.6 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EPE31159.1 - 0.0014 17.8 1.4 0.003 16.8 0.1 2.3 2 0 0 2 2 2 1 EF hand TBPIP PF07106.8 EPE31159.1 - 0.041 13.4 4.0 1.5 8.3 0.9 2.6 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AKNA PF12443.3 EPE31159.1 - 0.043 13.8 2.2 1.9 8.5 0.2 2.4 1 1 0 2 2 2 0 AT-hook-containing transcription factor Phage_GP20 PF06810.6 EPE31159.1 - 0.11 11.9 2.8 0.25 10.7 1.9 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 ATG16 PF08614.6 EPE31159.1 - 0.19 11.5 6.5 0.56 9.9 0.3 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 EPE31159.1 - 0.24 11.3 4.7 1.4 8.9 0.2 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Mnd1 PF03962.10 EPE31159.1 - 1.2 8.7 5.9 3.5 7.2 4.2 1.7 1 1 0 1 1 1 0 Mnd1 family HET PF06985.6 EPE31160.1 - 1.3e-19 70.7 0.0 3.5e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CAMSAP_CH PF11971.3 EPE31160.1 - 0.011 15.3 0.0 0.041 13.5 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain zf-C2H2 PF00096.21 EPE31160.1 - 0.14 12.5 0.8 0.42 11.0 0.5 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type HET PF06985.6 EPE31161.1 - 7e-28 97.5 0.0 1.6e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pyr_redox_2 PF07992.9 EPE31163.1 - 1.1e-15 58.0 0.4 4e-15 56.2 0.3 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE31163.1 - 1e-13 51.4 0.2 1.8e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE31163.1 - 2e-05 24.7 1.0 0.00055 20.0 0.1 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE31163.1 - 0.00015 20.8 3.2 0.14 11.0 0.1 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EPE31163.1 - 0.0007 18.6 0.8 0.00098 18.1 0.1 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPE31163.1 - 0.0021 17.8 0.1 11 5.7 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding TrkA_N PF02254.13 EPE31163.1 - 0.005 16.8 0.1 0.71 9.8 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain Trp_halogenase PF04820.9 EPE31163.1 - 0.013 14.1 1.3 0.028 13.0 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 EPE31163.1 - 0.029 14.6 0.2 1.6 9.0 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EPE31163.1 - 0.066 12.1 0.2 4 6.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 EPE31163.1 - 0.083 11.3 3.4 6.2 5.1 0.1 3.1 3 0 0 3 3 3 0 HI0933-like protein TIM PF00121.13 EPE31164.1 - 4.4e-47 160.1 0.0 5.3e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 EPE31165.1 - 8e-42 142.1 0.0 9.3e-42 141.9 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2620 PF10941.3 EPE31165.1 - 0.038 14.0 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2620 Gly_rich_SFCGS PF14272.1 EPE31165.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycine-rich SFCGS CorA PF01544.13 EPE31166.1 - 6.9e-09 35.1 1.8 6.9e-09 35.1 1.3 1.8 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Abhydrolase_6 PF12697.2 EPE31167.1 - 1.3e-25 90.5 0.0 2.6e-25 89.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE31167.1 - 1.7e-16 60.4 0.0 1.7e-15 57.2 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE31167.1 - 9e-13 48.2 0.0 9.2e-11 41.6 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 EPE31167.1 - 5.6e-06 25.6 0.0 1.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EPE31167.1 - 3e-05 23.5 0.0 5.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 EPE31167.1 - 0.00013 20.9 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.15 EPE31167.1 - 0.00079 19.7 0.0 0.073 13.2 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.20 EPE31167.1 - 0.00086 18.9 0.0 0.0022 17.5 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) DUF2305 PF10230.4 EPE31167.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_2 PF02230.11 EPE31167.1 - 0.007 15.8 0.0 12 5.2 0.0 3.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 EPE31167.1 - 0.008 16.0 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EPE31167.1 - 0.012 14.4 0.0 0.036 12.8 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase PGAP1 PF07819.8 EPE31167.1 - 0.024 14.2 0.0 0.057 12.9 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_3 PF07859.8 EPE31167.1 - 0.14 11.7 0.0 0.43 10.1 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Spo7 PF03907.8 EPE31168.1 - 4.5e-74 248.5 0.0 5.8e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein Transketolase_N PF00456.16 EPE31169.1 - 4.6e-16 58.5 2.5 7.6e-15 54.5 1.7 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 EPE31169.1 - 2.3e-09 37.2 0.0 6.2e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 EPE31169.1 - 0.00031 20.2 0.2 0.00069 19.1 0.2 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 EPE31169.1 - 0.0011 18.5 0.1 0.0068 15.9 0.1 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF3414 PF11894.3 EPE31170.1 - 0.015 12.2 0.1 0.017 12.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) RINT1_TIP1 PF04437.8 EPE31170.1 - 0.079 11.5 0.0 0.087 11.3 0.0 1.0 1 0 0 1 1 1 0 RINT-1 / TIP-1 family GrpE PF01025.14 EPE31172.1 - 0.00063 19.3 0.7 0.00086 18.8 0.5 1.1 1 0 0 1 1 1 1 GrpE TMF_DNA_bd PF12329.3 EPE31172.1 - 0.0042 16.8 0.3 0.0076 16.0 0.2 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding GAS PF13851.1 EPE31172.1 - 0.0062 15.7 0.3 0.0085 15.3 0.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Blo-t-5 PF11642.3 EPE31172.1 - 0.044 13.5 0.2 0.071 12.8 0.1 1.4 1 1 0 1 1 1 0 Mite allergen Blo t 5 Imm25 PF15571.1 EPE31172.1 - 0.057 13.5 0.2 0.076 13.1 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 25 Ax_dynein_light PF10211.4 EPE31172.1 - 0.064 13.0 0.1 0.071 12.9 0.1 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DUF2555 PF10742.4 EPE31172.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) DivIC PF04977.10 EPE31172.1 - 0.15 11.5 1.0 0.23 10.9 0.7 1.3 1 0 0 1 1 1 0 Septum formation initiator M PF02370.11 EPE31172.1 - 0.15 12.4 5.6 0.28 11.6 3.0 2.2 2 0 0 2 2 2 0 M protein repeat LysM PF01476.15 EPE31173.1 - 4.5e-05 23.2 0.0 8.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 LysM domain FmdA_AmdA PF03069.10 EPE31174.1 - 6.1e-48 163.3 0.0 2.2e-26 92.4 0.0 2.1 1 1 1 2 2 2 2 Acetamidase/Formamidase family TFCD_C PF12612.3 EPE31175.1 - 1.5e-22 79.9 4.4 1.8e-21 76.4 0.3 4.1 4 1 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 EPE31175.1 - 0.00011 22.3 7.7 0.27 11.5 0.0 5.7 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.17 EPE31175.1 - 0.0017 18.2 10.9 0.88 9.8 0.0 7.7 8 0 0 8 8 8 1 HEAT repeat Cnd1 PF12717.2 EPE31175.1 - 0.23 11.2 2.6 10 5.9 0.0 4.2 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EPE31175.1 - 0.71 10.4 21.6 0.6 10.6 0.1 7.0 8 0 0 8 8 8 0 HEAT-like repeat Abhydrolase_3 PF07859.8 EPE31176.1 - 8.6e-29 100.6 0.0 1.2e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EPE31176.1 - 0.00019 20.2 0.0 0.00023 19.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Fungal_trans PF04082.13 EPE31177.1 - 8.6e-14 51.0 0.1 1.8e-13 49.9 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE31177.1 - 1.1e-05 25.2 11.2 2.7e-05 23.9 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.23 EPE31178.1 - 3.3e-06 26.7 0.0 5.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GST_N_2 PF13409.1 EPE31180.1 - 6.8e-16 58.0 0.0 1.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE31180.1 - 1.3e-15 57.0 0.0 2.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPE31180.1 - 5.9e-09 35.8 0.1 1.2e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPE31180.1 - 0.00021 21.6 0.1 0.0004 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPE31180.1 - 0.025 14.8 0.1 0.35 11.1 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Abhydrolase_6 PF12697.2 EPE31181.1 - 7.8e-24 84.8 0.1 2e-23 83.5 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE31181.1 - 3.2e-10 39.9 0.0 9.2e-10 38.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE31181.1 - 4.5e-07 29.6 0.1 3.7e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EPE31181.1 - 0.00026 19.5 0.0 0.00095 17.7 0.0 1.8 2 0 0 2 2 2 1 Ndr family Hydrolase_4 PF12146.3 EPE31181.1 - 0.00034 20.3 0.0 0.00066 19.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EPE31181.1 - 0.015 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 EPE31181.1 - 0.019 13.8 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme AXE1 PF05448.7 EPE31181.1 - 0.081 11.4 0.0 0.15 10.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) CsbD PF05532.7 EPE31182.1 - 0.11 12.1 0.3 0.17 11.6 0.2 1.2 1 0 0 1 1 1 0 CsbD-like MFS_1 PF07690.11 EPE31184.1 - 1.2e-28 99.8 62.2 9.1e-23 80.5 20.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YobH PF13996.1 EPE31184.1 - 1.1 9.2 6.2 0.19 11.6 0.7 2.4 3 0 0 3 3 3 0 YobH-like protein Trp_halogenase PF04820.9 EPE31185.1 - 5.6e-33 114.2 0.5 1.7e-17 63.2 0.2 2.5 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EPE31185.1 - 4e-12 45.8 0.0 7.8e-12 44.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EPE31185.1 - 6.3e-07 29.4 0.0 1.6e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPE31185.1 - 1.8e-05 24.0 0.8 1.8e-05 24.0 0.5 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE31185.1 - 3.5e-05 23.7 0.2 0.00024 21.0 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE31185.1 - 0.00012 21.0 0.3 0.00021 20.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EPE31185.1 - 0.00021 20.3 0.2 0.00064 18.6 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 EPE31185.1 - 0.00053 18.9 0.2 0.001 18.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPE31185.1 - 0.0011 17.5 0.1 0.0023 16.4 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein ThiF PF00899.16 EPE31185.1 - 0.026 14.3 1.5 0.093 12.5 0.5 2.1 2 0 0 2 2 2 0 ThiF family Pyr_redox_3 PF13738.1 EPE31185.1 - 0.03 14.3 0.2 0.11 12.5 0.1 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE31185.1 - 0.083 13.3 0.4 0.23 11.8 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE31185.1 - 0.12 11.4 0.1 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 Thi4 family C2 PF00168.25 EPE31186.1 - 1.6e-18 66.2 0.4 1.5e-10 40.7 0.0 3.1 3 0 0 3 3 3 2 C2 domain Vma12 PF11712.3 EPE31186.1 - 1.1 8.9 0.0 1.1 8.9 0.0 3.2 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ecm33 PF12454.3 EPE31187.1 - 0.081 12.8 0.5 0.27 11.1 0.3 2.0 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Ribonuclease_T2 PF00445.13 EPE31189.1 - 1.8e-46 158.1 0.2 4.1e-46 156.9 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease T2 family FHA PF00498.21 EPE31192.1 - 1.8e-05 24.7 0.1 5e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 FHA domain UPF0546 PF10639.4 EPE31194.1 - 0.011 15.5 0.1 0.049 13.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Serpentine_r_xa PF03383.10 EPE31194.1 - 0.046 13.4 1.6 0.056 13.2 0.5 1.6 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa ABC2_membrane PF01061.19 EPE31195.1 - 1.9e-96 321.2 54.5 2.6e-48 163.9 12.3 2.7 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EPE31195.1 - 4e-36 124.3 0.0 4.9e-17 62.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EPE31195.1 - 4.4e-32 109.8 6.0 8.3e-30 102.4 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EPE31195.1 - 1.4e-19 69.9 0.1 3.1e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EPE31195.1 - 2.1e-09 36.9 42.5 4.4e-06 25.9 12.4 3.0 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 EPE31195.1 - 8.4e-08 31.8 0.0 0.00015 21.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EPE31195.1 - 2.7e-06 27.2 0.1 0.045 13.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EPE31195.1 - 4.4e-06 26.8 0.2 0.0019 18.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EPE31195.1 - 5e-06 25.8 0.3 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPE31195.1 - 9.9e-05 21.7 1.3 0.021 14.3 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EPE31195.1 - 0.00011 23.0 0.0 0.44 11.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPE31195.1 - 0.00036 20.2 0.1 0.43 10.3 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain cobW PF02492.14 EPE31195.1 - 0.00046 19.6 0.9 0.18 11.2 0.2 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 EPE31195.1 - 0.00065 18.9 0.0 0.18 11.0 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EPE31195.1 - 0.0016 18.5 0.1 2 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EPE31195.1 - 0.0021 18.2 0.1 0.77 9.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EPE31195.1 - 0.0029 17.9 0.1 1.3 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EPE31195.1 - 0.0043 16.7 0.2 1.9 8.0 0.1 2.6 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 EPE31195.1 - 0.0053 16.4 0.0 0.58 9.8 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 EPE31195.1 - 0.01 15.7 0.2 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EPE31195.1 - 0.021 14.7 2.0 1.1 9.1 0.0 3.5 5 0 0 5 5 2 0 AAA domain Miro PF08477.8 EPE31195.1 - 0.1 13.0 0.0 14 6.2 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 EPE31195.1 - 0.12 11.4 0.0 4.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 EPE31195.1 - 0.15 11.8 0.5 12 5.5 0.2 3.0 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.1 EPE31195.1 - 0.17 11.4 0.3 5.3 6.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EPE31195.1 - 0.23 11.1 0.9 3.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EPE31195.1 - 0.48 9.8 2.1 5.4 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain RE_MjaI PF09568.5 EPE31198.1 - 0.046 13.2 0.2 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 MjaI restriction endonuclease Sugar_tr PF00083.19 EPE31199.1 - 3.8e-72 243.3 20.4 4.7e-72 243.0 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE31199.1 - 1.2e-16 60.3 26.4 9e-16 57.5 14.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Response_reg PF00072.19 EPE31201.1 - 6.1e-24 84.1 0.5 1.2e-23 83.2 0.3 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EPE31201.1 - 1.8e-23 82.3 0.1 5.5e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EPE31201.1 - 7e-19 68.1 0.0 2.2e-14 53.7 0.0 2.7 3 0 0 3 3 3 2 PAS domain HisKA PF00512.20 EPE31201.1 - 4.4e-16 58.6 0.1 1e-15 57.4 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EPE31201.1 - 1.6e-13 50.6 0.0 5.6e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 EPE31201.1 - 3.2e-11 42.9 0.0 9.5e-08 31.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 EPE31201.1 - 0.024 14.6 0.1 0.058 13.5 0.1 1.7 1 0 0 1 1 1 0 PAS fold Na_H_Exchanger PF00999.16 EPE31205.1 - 3.6e-28 98.1 43.9 8.3e-22 77.2 17.3 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family MFS_1_like PF12832.2 EPE31205.1 - 0.055 13.2 7.7 0.19 11.5 0.0 3.9 3 1 0 3 3 3 0 MFS_1 like family Thiolase_N PF00108.18 EPE31207.1 - 7.9e-92 306.9 2.1 1.2e-91 306.4 1.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPE31207.1 - 3e-36 123.5 0.9 3e-36 123.5 0.6 1.9 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EPE31207.1 - 0.0011 18.4 3.7 0.0024 17.3 1.1 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.21 EPE31208.1 - 3.4e-52 175.5 0.1 3.8e-52 175.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPE31208.1 - 5.5e-07 29.3 0.0 6.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPE31208.1 - 0.042 13.7 0.2 0.073 12.9 0.2 1.6 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 EPE31209.1 - 1.1e-113 379.3 4.0 2e-113 378.5 0.1 2.4 2 0 0 2 2 2 1 Kinesin motor domain XkdW PF09636.5 EPE31209.1 - 5.5 6.9 8.8 3.2 7.6 0.8 3.1 2 1 0 2 2 2 0 XkdW protein DUF1062 PF06353.7 EPE31210.1 - 0.039 14.1 0.1 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1062) DUF2244 PF10003.4 EPE31210.1 - 2 7.7 4.1 0.65 9.3 0.3 2.0 2 1 1 3 3 3 0 Integral membrane protein (DUF2244) HTH_Tnp_Tc5 PF03221.11 EPE31211.1 - 1.5e-19 69.5 1.5 0.00012 21.8 0.0 5.7 5 0 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.6 EPE31211.1 - 6.9e-13 48.0 1.3 1.9e-12 46.6 0.9 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EPE31211.1 - 0.0023 17.4 0.1 0.006 16.1 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 EPE31211.1 - 0.004 17.3 16.2 0.016 15.5 2.6 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_clus PF00172.13 EPE31211.1 - 0.065 13.1 6.8 0.5 10.3 0.6 2.5 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EPE31211.1 - 0.12 12.7 20.7 0.022 15.0 2.6 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type Transp_cyt_pur PF02133.10 EPE31212.1 - 2.9e-71 240.3 33.7 3.4e-71 240.1 23.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Bac_luciferase PF00296.15 EPE31213.1 - 1.2e-53 182.2 0.2 2.1e-53 181.4 0.2 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase Glyco_hydro_7 PF00840.15 EPE31214.1 - 1.5e-209 695.7 18.6 2.1e-209 695.3 12.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 EPE31214.1 - 4.4e-07 29.4 11.9 4.4e-07 29.4 8.2 4.5 5 1 0 5 5 5 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.1 EPE31216.1 - 3.9e-17 62.9 0.1 5.6e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE31216.1 - 1.9e-14 54.0 0.0 2.6e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EPE31216.1 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF563 PF04577.9 EPE31217.1 - 3.6e-24 85.8 0.1 5.5e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PIP49_N PF14875.1 EPE31217.1 - 0.45 10.1 1.5 27 4.3 0.0 2.4 2 0 0 2 2 2 0 N-term cysteine-rich ER, FAM69 NmrA PF05368.8 EPE31218.1 - 2.3e-20 72.8 0.0 2.8e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE31218.1 - 9.8e-10 38.7 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EPE31218.1 - 0.0065 16.7 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EPE31218.1 - 0.051 13.4 0.2 0.27 11.1 0.0 2.4 4 0 0 4 4 4 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EPE31218.1 - 0.063 12.6 0.0 0.29 10.5 0.0 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EPE31218.1 - 0.077 12.9 0.0 7.3 6.6 0.0 2.4 2 1 0 2 2 2 0 TrkA-N domain ThiF PF00899.16 EPE31218.1 - 0.72 9.6 4.4 23 4.8 0.4 3.0 2 1 1 3 3 3 0 ThiF family DUF2785 PF10978.3 EPE31219.1 - 0.075 12.4 0.3 0.16 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) GalP_UDP_transf PF01087.17 EPE31220.1 - 2.5e-70 236.2 0.1 4.1e-68 229.0 0.0 2.6 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EPE31220.1 - 1.1e-55 187.7 0.0 2.2e-55 186.7 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EPE31220.1 - 0.0042 17.6 0.0 0.016 15.7 0.0 1.9 2 0 0 2 2 2 1 HIT domain Filament PF00038.16 EPE31220.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein Erg28 PF03694.8 EPE31221.1 - 2.8e-34 117.4 0.4 3.8e-34 117.0 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.20 EPE31222.1 - 3.3e-21 75.9 0.0 4.6e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE31222.1 - 2e-09 37.6 0.0 2.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE31222.1 - 3e-05 23.7 0.1 5.7e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPE31222.1 - 0.00059 18.8 0.1 0.00074 18.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EPE31222.1 - 0.0036 17.3 0.1 0.009 16.0 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Nucleoporin_C PF03177.9 EPE31223.1 - 2.1e-129 432.7 10.7 3e-129 432.1 7.4 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EPE31223.1 - 1.9e-93 313.5 0.3 2.4e-93 313.1 0.2 1.1 1 0 0 1 1 1 1 Nup133 N terminal like DUF659 PF04937.10 EPE31223.1 - 0.077 12.4 0.1 0.32 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) Glyco_hydro_3 PF00933.16 EPE31224.1 - 3.9e-85 285.4 0.0 5.9e-85 284.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE31224.1 - 3.8e-49 167.2 0.2 6e-49 166.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE31224.1 - 5.9e-24 83.8 0.0 1.2e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pro_CA PF00484.14 EPE31225.1 - 2.2e-10 40.7 0.0 2.6e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DUF3328 PF11807.3 EPE31226.1 - 2.4e-26 92.7 1.3 3.4e-26 92.2 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2342 PF10103.4 EPE31226.1 - 0.029 13.3 0.2 0.052 12.5 0.1 1.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2342) DUF3328 PF11807.3 EPE31227.1 - 8.5e-25 87.7 0.1 9.9e-25 87.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EPE31229.1 - 3.2e-19 69.4 0.0 4.4e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.3 EPE31230.1 - 2.3e-53 181.1 2.6 2.8e-53 180.8 1.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE31230.1 - 1.9e-08 34.0 8.7 1.9e-08 34.0 6.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3328 PF11807.3 EPE31231.1 - 4e-33 114.9 0.0 4.4e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EPE31232.1 - 4e-20 71.8 17.6 1e-11 44.1 1.0 2.4 2 1 1 3 3 3 3 Major Facilitator Superfamily Asp PF00026.18 EPE31236.1 - 4.9e-32 111.4 0.0 2.6e-31 109.0 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EPE31236.1 - 0.00019 20.9 0.0 0.00056 19.4 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal HTHP PF11534.3 EPE31237.1 - 0.11 12.5 0.1 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Hexameric tyrosine-coordinated heme protein (HTHP) Alk_phosphatase PF00245.15 EPE31238.1 - 1.2e-61 208.7 0.0 1.5e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Alk_phosphatase PF00245.15 EPE31239.1 - 3.1e-19 68.9 0.0 4.1e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase IBR PF01485.16 EPE31241.1 - 1.7e-07 30.9 35.3 0.00032 20.5 4.0 3.4 3 0 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EPE31241.1 - 0.0055 16.7 6.5 0.0055 16.7 4.5 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE31241.1 - 0.007 16.1 5.4 0.007 16.1 3.7 3.9 4 0 0 4 4 4 1 Ring finger domain tRNA-synt_1g PF09334.6 EPE31241.1 - 0.4 9.2 1.3 1.9 7.0 0.7 1.8 1 1 1 2 2 2 0 tRNA synthetases class I (M) HAUS6_N PF14661.1 EPE31242.1 - 3e-53 180.7 4.0 3e-53 180.7 2.7 1.8 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Glyco_hydro_72 PF03198.9 EPE31243.1 - 2.7e-128 427.3 5.3 3.5e-128 427.0 3.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase ECH PF00378.15 EPE31243.1 - 5.4e-48 163.2 0.1 9.1e-48 162.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Cellulase PF00150.13 EPE31243.1 - 9.1e-05 21.7 0.9 0.00026 20.3 0.6 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rieske PF00355.21 EPE31244.1 - 0.088 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain DUF3328 PF11807.3 EPE31245.1 - 1.4e-36 126.2 2.0 1.7e-36 125.9 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EPE31246.1 - 1.8e-42 145.5 1.0 2.8e-42 144.8 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EPE31247.1 - 6.1e-50 169.9 2.6 8.5e-50 169.4 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) CsbD PF05532.7 EPE31248.1 - 0.0059 16.2 22.1 24 4.7 0.0 10.1 12 0 0 12 12 12 2 CsbD-like Tox-MPTase3 PF15639.1 EPE31248.1 - 0.01 15.6 9.3 9.7 5.9 2.2 5.4 1 1 2 3 3 3 0 Metallopeptidase toxin 3 Apelin PF15360.1 EPE31248.1 - 0.012 15.7 0.8 28 5.0 0.0 4.4 1 1 4 5 5 5 0 APJ endogenous ligand Inhibitor_I69 PF13734.1 EPE31248.1 - 0.037 14.1 0.9 18 5.5 0.0 3.3 2 1 1 3 3 3 0 Spi protease inhibitor DUF4173 PF13777.1 EPE31249.1 - 0.002 17.4 0.0 0.0023 17.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4173) Baculo_11_kDa PF06143.6 EPE31249.1 - 0.047 13.0 1.2 0.069 12.5 0.8 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF2141 PF09912.4 EPE31249.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) DHO_dh PF01180.16 EPE31250.1 - 4.4e-67 226.1 0.4 6.6e-52 176.3 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EPE31250.1 - 0.00053 18.9 0.2 0.71 8.6 0.0 2.5 2 1 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.12 EPE31250.1 - 0.0017 17.6 4.4 0.24 10.6 0.0 2.7 3 0 0 3 3 3 2 PcrB family Lipase_GDSL_2 PF13472.1 EPE31250.1 - 0.024 14.7 0.1 0.078 13.0 0.0 1.9 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Coatomer_WDAD PF04053.9 EPE31251.1 - 2e-174 580.5 0.0 7.2e-174 578.7 0.0 1.8 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EPE31251.1 - 6.4e-47 155.8 8.3 2.1e-10 40.0 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EPE31251.1 - 7.3e-05 21.0 2.8 0.024 12.7 0.1 3.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EPE31251.1 - 0.0014 18.3 0.0 2.6 7.8 0.0 3.5 2 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region YmzC PF14157.1 EPE31251.1 - 0.11 12.3 0.1 76 3.2 0.0 4.3 5 0 0 5 5 5 0 YmzC-like protein Mannitol_dh_C PF08125.8 EPE31252.1 - 1.3e-47 162.0 0.1 1.9e-47 161.5 0.1 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EPE31252.1 - 3.6e-19 69.2 0.2 3.6e-19 69.2 0.1 2.2 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 EPE31252.1 - 0.00064 19.4 6.4 0.0031 17.1 0.0 3.3 3 1 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EPE31252.1 - 0.027 13.8 1.5 0.053 12.9 0.2 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EPE31252.1 - 0.056 13.8 0.2 0.79 10.1 0.2 2.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ring_hydroxyl_A PF00848.14 EPE31254.1 - 0.027 14.1 0.3 0.055 13.1 0.2 1.5 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Rhodanese PF00581.15 EPE31255.1 - 3.5e-10 40.2 0.1 7.4e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain DUF1996 PF09362.5 EPE31257.1 - 1.9e-79 266.6 3.4 3.1e-79 265.9 2.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) COesterase PF00135.23 EPE31258.1 - 5e-94 315.9 0.1 5.3e-94 315.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE31258.1 - 2.4e-05 24.0 0.1 5.3e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE31258.1 - 5.8e-05 22.4 0.4 0.00011 21.5 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family F-box-like PF12937.2 EPE31259.1 - 8.8e-06 25.3 0.8 2.1e-05 24.1 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE31259.1 - 0.00013 21.5 1.6 0.00026 20.5 1.1 1.5 1 0 0 1 1 1 1 F-box domain APH PF01636.18 EPE31261.1 - 1.1e-16 61.3 0.0 1.3e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPE31261.1 - 2e-05 24.0 0.1 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EPE31261.1 - 0.0027 17.3 0.0 0.0052 16.3 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase SchA_CurD PF04486.7 EPE31261.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 SchA/CurD like domain Pkinase_Tyr PF07714.12 EPE31261.1 - 0.12 11.4 0.0 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase EcKinase PF02958.15 EPE31261.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Fructosamin_kin PF03881.9 EPE31261.1 - 0.35 9.8 1.5 1.7 7.5 0.0 2.4 2 1 1 3 3 3 0 Fructosamine kinase HD_3 PF13023.1 EPE31263.1 - 9.4e-46 155.5 1.1 6.4e-45 152.8 0.0 2.0 1 1 1 2 2 2 1 HD domain Nucleoplasmin PF03066.10 EPE31265.1 - 0.0017 17.8 0.7 0.0027 17.2 0.5 1.3 1 0 0 1 1 1 1 Nucleoplasmin CENP-B_dimeris PF09026.5 EPE31265.1 - 0.027 14.6 3.5 0.049 13.8 2.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EPE31265.1 - 0.081 12.5 2.5 0.12 11.9 1.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 EPE31265.1 - 2 7.0 7.7 2.9 6.5 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 EPE31265.1 - 2.2 8.6 8.6 4.1 7.7 6.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PWI PF01480.12 EPE31269.1 - 4.6e-08 33.0 0.1 1.4e-07 31.4 0.1 1.9 1 0 0 1 1 1 1 PWI domain Ribosomal_S21 PF01165.15 EPE31270.1 - 5.4e-10 38.5 2.5 1.1e-09 37.6 1.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 Mucin PF01456.12 EPE31270.1 - 0.72 9.6 13.5 1.1 9.0 9.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Pol_alpha_B_N PF08418.5 EPE31270.1 - 6.7 6.1 11.6 9.4 5.6 8.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Fungal_trans PF04082.13 EPE31271.1 - 1.9e-05 23.6 0.0 2.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SWIRM PF04433.12 EPE31274.1 - 1e-11 44.8 0.0 4.1e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 EPE31274.1 - 1.3e-09 37.4 3.9 1.3e-09 37.4 2.7 1.9 2 0 0 2 2 2 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EPE31274.1 - 9e-07 28.8 0.0 2.9e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cobl PF09469.5 EPE31274.1 - 0.016 15.2 0.2 0.058 13.3 0.1 2.0 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Pkinase PF00069.20 EPE31275.1 - 3.9e-71 239.2 0.0 5.2e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE31275.1 - 1e-34 119.8 0.0 1.6e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EPE31275.1 - 8.1e-10 39.0 1.5 1.8e-09 37.9 1.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPE31275.1 - 0.001 18.0 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PGI PF00342.14 EPE31276.1 - 6.3e-215 714.1 0.1 7.2e-215 713.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase zf-LITAF-like PF10601.4 EPE31278.1 - 1.4e-21 76.1 3.4 2e-21 75.6 2.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-ribbon_3 PF13248.1 EPE31278.1 - 0.0085 15.2 1.2 1.4 8.2 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EPE31278.1 - 0.018 15.0 0.5 0.073 13.0 0.0 2.0 2 0 0 2 2 2 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 EPE31278.1 - 0.029 13.8 0.5 0.49 9.8 0.0 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit HET PF06985.6 EPE31279.1 - 1.9e-25 89.6 0.0 3.7e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FSH1 PF03959.8 EPE31280.1 - 1.6e-21 76.7 0.0 1.8e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EPE31280.1 - 3.9e-05 23.4 0.0 7.4e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE31280.1 - 0.00042 20.2 0.0 0.033 14.0 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE31280.1 - 0.0031 17.0 0.3 0.077 12.4 0.2 2.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase HET PF06985.6 EPE31281.1 - 2.7e-22 79.4 0.1 4.4e-22 78.7 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2781 PF10914.3 EPE31283.1 - 7.7e-36 123.1 10.4 8.8e-36 122.9 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Sugar_tr PF00083.19 EPE31285.1 - 9.6e-76 255.1 9.6 1.1e-75 254.9 6.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE31285.1 - 1.4e-32 112.7 26.5 1.2e-29 103.0 8.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE31285.1 - 0.0012 17.3 1.2 0.0012 17.3 0.8 2.8 2 2 0 2 2 2 2 MFS/sugar transport protein CorA PF01544.13 EPE31286.1 - 0.0035 16.4 0.0 0.0064 15.5 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_M4_C PF02868.10 EPE31287.1 - 2.2e-43 147.8 0.1 3.7e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 EPE31287.1 - 1.4e-27 96.6 0.3 2.5e-27 95.8 0.2 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain DUF1002 PF06207.6 EPE31287.1 - 0.02 14.2 0.1 0.035 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) YopJ PF03421.11 EPE31287.1 - 0.08 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase Asp PF00026.18 EPE31288.1 - 2e-29 102.8 0.0 7.6e-25 87.8 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Phage_lysozyme PF00959.14 EPE31289.1 - 3.8e-13 49.6 0.0 5.8e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Phage lysozyme DNA_binding_1 PF01035.15 EPE31290.1 - 0.0016 18.1 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain SNF2_N PF00176.18 EPE31291.1 - 2.7e-69 233.2 0.0 3.9e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE31291.1 - 2.1e-11 43.5 0.0 6.1e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPE31291.1 - 8.6e-07 28.5 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EPE31291.1 - 1.2e-05 24.8 4.9 2.2e-05 24.0 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EPE31291.1 - 0.01 15.3 0.3 0.027 13.9 0.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.1 EPE31291.1 - 0.033 13.8 5.2 0.084 12.5 3.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE31291.1 - 0.45 10.3 2.7 1 9.2 1.9 1.7 1 0 0 1 1 1 0 Ring finger domain PI3_PI4_kinase PF00454.22 EPE31292.1 - 1.3e-40 139.3 0.0 1.9e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UBN_AB PF14075.1 EPE31292.1 - 0.1 12.2 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Methyltransf_8 PF05148.10 EPE31293.1 - 8.7e-59 198.7 0.0 7.3e-57 192.5 0.0 2.7 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EPE31293.1 - 3e-05 24.4 0.0 0.00012 22.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE31293.1 - 0.0071 15.9 0.1 4.6 6.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 EPE31293.1 - 0.017 14.4 0.0 1.2 8.4 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase small domain Methyltransf_32 PF13679.1 EPE31293.1 - 0.07 12.8 0.0 0.07 12.8 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Lamp PF01299.12 EPE31293.1 - 0.16 11.1 3.0 0.3 10.2 2.1 1.4 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Asp_protease PF09668.5 EPE31294.1 - 1.1e-62 209.1 0.2 1.7e-62 208.5 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EPE31294.1 - 8.3e-13 48.6 0.1 4.5e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.18 EPE31294.1 - 9.6e-12 44.1 0.0 1.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.6 EPE31294.1 - 1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.26 EPE31294.1 - 1.3e-07 31.2 0.0 3.4e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain gag-asp_proteas PF13975.1 EPE31294.1 - 7e-07 28.9 1.0 2.1e-06 27.4 0.0 2.3 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EPE31294.1 - 9.5e-05 22.2 0.0 0.00067 19.5 0.0 2.3 2 1 0 2 2 2 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 EPE31294.1 - 0.0001 21.9 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RuvA_C PF07499.8 EPE31294.1 - 0.00092 19.3 0.0 0.0032 17.5 0.0 1.9 1 0 0 1 1 1 1 RuvA, C-terminal domain UN_NPL4 PF11543.3 EPE31294.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 UBA_4 PF14555.1 EPE31294.1 - 0.015 14.8 0.4 0.05 13.1 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain YukD PF08817.5 EPE31294.1 - 0.036 14.6 0.1 0.091 13.3 0.1 1.7 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD RRM_6 PF14259.1 EPE31296.1 - 2e-11 43.6 0.0 4.6e-10 39.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE31296.1 - 1.2e-07 31.5 0.0 4.3e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE31296.1 - 8.2e-07 28.5 0.1 3.9e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPE31296.1 - 2e-06 27.4 0.0 0.00015 21.4 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif PWI PF01480.12 EPE31296.1 - 0.00016 21.6 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 EPE31296.1 - 0.011 15.3 4.6 0.02 14.5 3.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1330 PF07045.6 EPE31296.1 - 0.096 12.5 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) Seryl_tRNA_N PF02403.17 EPE31296.1 - 0.41 10.6 13.5 0.82 9.7 9.3 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.1 EPE31296.1 - 9.8 6.4 8.7 17 5.6 6.0 1.3 1 0 0 1 1 1 0 AAA domain Xpo1 PF08389.7 EPE31297.1 - 2.6e-28 98.7 1.5 1.3e-26 93.3 0.3 3.4 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EPE31297.1 - 6.6e-06 25.9 0.1 1.8e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 EPE31297.1 - 0.00086 17.7 0.7 0.44 8.7 0.1 2.8 2 1 0 2 2 2 2 Adaptin N terminal region F-box-like PF12937.2 EPE31297.1 - 0.031 13.9 0.2 0.21 11.3 0.1 2.4 2 0 0 2 2 2 0 F-box-like LSM PF01423.17 EPE31298.1 - 1.1e-15 56.9 0.1 1.4e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain PhnA PF03831.9 EPE31298.1 - 0.036 13.4 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 PhnA protein 5-FTHF_cyc-lig PF01812.15 EPE31299.1 - 4.3e-33 114.6 0.0 6.7e-33 114.0 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.4 EPE31300.1 - 1.7e-86 289.0 0.1 2e-86 288.7 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal His_Phos_2 PF00328.17 EPE31301.1 - 1.5e-55 188.9 0.0 1.8e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Iso_dh PF00180.15 EPE31302.1 - 2.9e-97 325.7 0.0 3.6e-97 325.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sec5 PF15469.1 EPE31303.1 - 3.7e-37 127.8 0.0 5e-36 124.1 0.0 2.6 2 1 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EPE31303.1 - 1.4e-06 28.0 6.4 9e-06 25.4 0.1 3.9 3 1 0 3 3 3 1 Vps51/Vps67 PGI PF00342.14 EPE31303.1 - 0.059 11.7 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoglucose isomerase Trypsin_2 PF13365.1 EPE31304.1 - 6.5e-17 61.6 0.0 1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EPE31304.1 - 1.1e-07 31.6 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Peptidase_S32 PF05579.8 EPE31304.1 - 0.00086 18.3 0.1 0.0028 16.6 0.0 1.7 2 0 0 2 2 2 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.4 EPE31304.1 - 0.072 11.5 0.1 4.8 5.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase S46 Zn_clus PF00172.13 EPE31305.1 - 3.9 7.4 15.0 0.32 10.9 6.8 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain YqeY PF09424.5 EPE31306.1 - 3.7e-23 81.9 0.9 4.3e-23 81.7 0.6 1.0 1 0 0 1 1 1 1 Yqey-like protein Fungal_trans_2 PF11951.3 EPE31307.1 - 5e-15 54.9 1.4 1.2e-13 50.4 0.9 2.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE31307.1 - 3.3e-06 26.8 12.7 6.1e-06 26.0 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AIG2 PF06094.7 EPE31308.1 - 1.2e-11 44.9 0.0 1.7e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family Abhydrolase_6 PF12697.2 EPE31309.1 - 3.2e-32 112.2 0.0 4.7e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE31309.1 - 9.3e-12 44.9 0.1 6.1e-11 42.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE31309.1 - 8.8e-08 32.0 0.0 1e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EPE31309.1 - 1.1e-05 24.1 0.0 1.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EPE31309.1 - 0.0003 20.5 0.0 0.00067 19.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EPE31309.1 - 0.0039 16.1 0.1 0.0078 15.1 0.1 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPE31309.1 - 0.0095 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Ribosomal_L18_c PF14204.1 EPE31309.1 - 0.088 13.3 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region ADH_N PF08240.7 EPE31310.1 - 6.1e-08 32.4 0.3 1.1e-07 31.5 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE31310.1 - 1e-06 28.3 0.1 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MTHFR PF02219.12 EPE31311.1 - 1.5e-115 385.2 0.0 2.7e-115 384.3 0.0 1.4 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase Spc97_Spc98 PF04130.8 EPE31312.1 - 6.2e-125 417.5 0.7 1e-124 416.8 0.5 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family PspA_IM30 PF04012.7 EPE31312.1 - 0.25 10.6 1.6 6.9 5.9 0.2 2.3 2 0 0 2 2 2 0 PspA/IM30 family Proteasome PF00227.21 EPE31313.1 - 7.6e-56 188.4 0.0 9.7e-56 188.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPE31313.1 - 1.2e-13 50.1 0.0 2.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EPE31313.1 - 0.0076 15.9 0.2 0.2 11.3 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3137) Pro_CA PF00484.14 EPE31314.1 - 2.3e-11 43.9 0.0 3.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Ank_2 PF12796.2 EPE31315.1 - 7.3e-30 103.1 0.7 2.1e-13 50.4 0.0 6.1 3 2 2 6 6 6 5 Ankyrin repeats (3 copies) Pkinase PF00069.20 EPE31315.1 - 2.4e-27 95.7 0.0 3.9e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.1 EPE31315.1 - 2.6e-24 85.1 7.5 2.5e-07 31.0 0.1 8.3 6 2 1 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.25 EPE31315.1 - 3.2e-21 74.0 7.1 1e-05 25.0 0.0 8.7 9 1 0 9 9 9 4 Ankyrin repeat Pkinase_Tyr PF07714.12 EPE31315.1 - 1.1e-18 67.3 0.0 2.8e-18 65.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_5 PF13857.1 EPE31315.1 - 7.6e-17 60.9 11.4 0.00032 20.8 0.0 9.0 6 3 3 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE31315.1 - 5.9e-16 56.9 3.5 0.00016 21.6 0.0 9.5 9 0 0 9 9 9 2 Ankyrin repeat RVP PF00077.15 EPE31315.1 - 0.028 14.3 0.1 22 5.0 0.0 3.2 3 0 0 3 3 3 0 Retroviral aspartyl protease Kinase-like PF14531.1 EPE31315.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 EPE31315.1 - 0.41 9.3 0.6 0.8 8.4 0.1 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EPE31318.1 - 0.00061 19.0 0.0 0.00098 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE31318.1 - 0.019 14.0 0.0 0.064 12.3 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase Peptidase_C14 PF00656.17 EPE31318.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Caspase domain GMC_oxred_N PF00732.14 EPE31319.1 - 1.1e-52 179.0 0.0 1.4e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE31319.1 - 7.1e-28 97.6 0.0 1.3e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EPE31319.1 - 6.5e-06 25.2 0.1 0.0014 17.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EPE31319.1 - 6.1e-05 22.0 0.1 0.08 11.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE31319.1 - 0.00028 19.9 0.1 0.00045 19.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPE31319.1 - 0.0024 17.9 0.0 0.083 12.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPE31319.1 - 0.0027 16.6 0.0 0.84 8.4 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EPE31319.1 - 0.0029 16.7 0.1 0.0047 16.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EPE31319.1 - 0.0035 17.2 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE31319.1 - 0.086 12.8 0.4 0.26 11.3 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain PriCT_1 PF08708.6 EPE31320.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) ASCH PF04266.9 EPE31321.1 - 0.0058 16.9 0.0 0.0078 16.5 0.0 1.3 1 0 0 1 1 1 1 ASCH domain adh_short_C2 PF13561.1 EPE31322.1 - 1.2e-15 57.9 0.0 1.5e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE31322.1 - 2.1e-13 50.5 1.2 2.6e-13 50.2 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EPE31322.1 - 0.00011 22.2 0.7 0.0002 21.4 0.3 1.6 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_7 PF13241.1 EPE31322.1 - 0.0007 19.8 0.2 0.0027 17.9 0.1 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding KR PF08659.5 EPE31322.1 - 0.0022 17.6 0.4 0.003 17.2 0.3 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EPE31322.1 - 0.0027 17.3 0.1 0.0048 16.5 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EPE31322.1 - 0.0028 17.6 0.2 0.0063 16.5 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.14 EPE31322.1 - 0.063 12.3 0.1 0.15 11.1 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox PF00070.22 EPE31322.1 - 0.076 13.4 0.2 0.26 11.7 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ORC4_C PF14629.1 EPE31323.1 - 1.6e-49 168.0 0.0 3e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus PHD_2 PF13831.1 EPE31323.1 - 3.8e-10 38.9 2.5 8.5e-10 37.7 1.7 1.6 1 0 0 1 1 1 1 PHD-finger PHD PF00628.24 EPE31323.1 - 5.7e-10 38.7 6.8 1e-09 37.9 4.7 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EPE31323.1 - 8.4e-06 25.4 0.5 8.4e-06 25.4 0.3 1.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 EPE31323.1 - 0.013 15.4 3.1 0.015 15.2 1.0 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger SAE2 PF08573.5 EPE31323.1 - 0.022 15.4 0.2 0.16 12.6 0.1 2.6 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Prok-RING_1 PF14446.1 EPE31323.1 - 0.16 11.7 1.2 0.33 10.7 0.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 ABM PF03992.11 EPE31327.1 - 0.00012 22.0 2.0 0.0025 17.8 0.1 2.5 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase AMP-binding PF00501.23 EPE31328.1 - 2.6e-82 276.4 0.0 4.1e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE31328.1 - 0.04 14.8 0.0 0.09 13.7 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.4 EPE31329.1 - 1.8e-16 60.1 1.0 2.3e-14 53.2 0.7 2.1 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EPE31329.1 - 0.0012 18.1 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Pex19 PF04614.7 EPE31329.1 - 0.058 12.9 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 Pex19 protein family adh_short PF00106.20 EPE31330.1 - 7.6e-62 208.1 7.3 1.1e-30 106.8 0.6 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EPE31330.1 - 3e-30 105.2 1.6 2.1e-15 56.8 0.1 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EPE31330.1 - 7.7e-27 93.1 0.0 1.6e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EPE31330.1 - 5e-07 29.5 0.0 2e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Epimerase PF01370.16 EPE31330.1 - 0.00044 19.7 3.0 0.007 15.8 0.1 2.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EPE31330.1 - 0.0084 15.2 3.5 0.011 14.7 0.1 2.5 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 EPE31330.1 - 0.04 14.2 0.6 6.4 7.0 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) AAA_17 PF13207.1 EPE31331.1 - 1.8e-05 25.5 0.0 0.00014 22.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EPE31331.1 - 4.1e-05 23.2 0.0 7.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ArgK PF03308.11 EPE31331.1 - 0.00022 20.1 0.0 0.00045 19.0 0.0 1.4 1 0 0 1 1 1 1 ArgK protein SRP54 PF00448.17 EPE31331.1 - 0.00032 20.1 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KAP_NTPase PF07693.9 EPE31331.1 - 0.00034 19.7 0.0 0.00049 19.2 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain Zeta_toxin PF06414.7 EPE31331.1 - 0.00072 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EPE31331.1 - 0.0012 18.8 0.0 0.0042 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EPE31331.1 - 0.002 17.6 0.1 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EPE31331.1 - 0.0022 18.3 0.2 0.0049 17.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EPE31331.1 - 0.0038 16.9 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase UPF0079 PF02367.12 EPE31331.1 - 0.0047 16.5 0.1 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SCA7 PF08313.7 EPE31331.1 - 0.01 15.4 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 SCA7, zinc-binding domain Thymidylate_kin PF02223.12 EPE31331.1 - 0.014 14.7 0.1 0.029 13.7 0.1 1.5 1 0 0 1 1 1 0 Thymidylate kinase ABC_tran PF00005.22 EPE31331.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 EPE31331.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPE31331.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EPE31331.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EPE31331.1 - 0.072 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 EPE31331.1 - 0.12 12.0 0.3 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.1 EPE31331.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ECM11 PF15463.1 EPE31332.1 - 7.1e-25 87.9 8.6 7.1e-25 87.9 6.0 3.3 2 1 1 3 3 3 1 Extracellular mutant protein 11 Glutaredoxin2_C PF04399.8 EPE31332.1 - 0.52 9.8 4.4 0.51 9.9 1.3 2.1 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain TROVE PF05731.6 EPE31332.1 - 2.1 7.0 9.8 0.13 10.9 3.3 1.5 2 0 0 2 2 2 0 TROVE domain GTP_EFTU PF00009.22 EPE31333.1 - 1.7e-62 210.2 0.1 2.4e-62 209.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPE31333.1 - 2.9e-37 126.8 0.0 8.1e-37 125.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EPE31333.1 - 4.5e-22 77.7 0.0 1.2e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPE31333.1 - 2e-11 43.8 3.0 2.2e-11 43.6 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EPE31333.1 - 5.3e-11 42.2 0.1 3e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EPE31333.1 - 2.7e-05 24.1 0.2 5.3e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EPE31333.1 - 0.076 12.4 0.2 0.29 10.6 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Xan_ur_permease PF00860.15 EPE31334.1 - 1.1 7.6 0.2 1.8 6.9 0.1 1.2 1 0 0 1 1 1 0 Permease family Solute_trans_a PF03619.11 EPE31335.1 - 2.3e-89 299.3 1.5 3.3e-89 298.8 1.0 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Methyltransf_23 PF13489.1 EPE31336.1 - 2.6e-08 33.7 0.1 4.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE31336.1 - 5.6e-07 29.9 0.1 2.3e-06 28.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE31336.1 - 0.00044 20.5 0.0 0.0011 19.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE31336.1 - 0.0069 15.9 0.0 0.096 12.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE31336.1 - 0.0087 16.0 0.0 0.034 14.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE31336.1 - 0.063 13.7 0.0 0.17 12.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EPE31336.1 - 0.092 13.3 0.0 0.42 11.1 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EPE31336.1 - 0.12 12.3 0.0 0.89 9.5 0.0 2.2 2 0 0 2 2 2 0 FtsJ-like methyltransferase Lon_C PF05362.8 EPE31337.1 - 3.3e-62 209.4 0.0 9e-62 208.0 0.0 1.8 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EPE31337.1 - 2.8e-38 131.6 0.1 8.1e-38 130.1 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EPE31337.1 - 2e-22 79.7 0.0 4.7e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE31337.1 - 3e-06 27.4 0.1 0.00013 22.1 0.1 2.9 1 1 0 1 1 1 1 AAA domain ChlI PF13541.1 EPE31337.1 - 1.2e-05 24.8 0.0 3.4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EPE31337.1 - 1.3e-05 24.9 0.0 3.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPE31337.1 - 2.3e-05 25.1 0.1 0.00031 21.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.6 EPE31337.1 - 0.00011 21.0 0.0 0.0002 20.1 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.7 EPE31337.1 - 0.00015 20.8 0.0 0.0011 18.0 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPE31337.1 - 0.0019 18.2 7.3 0.0033 17.4 0.0 3.7 4 1 0 4 4 4 1 AAA ATPase domain AAA_14 PF13173.1 EPE31337.1 - 0.0073 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EPE31337.1 - 0.015 14.6 0.1 0.057 12.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 EPE31337.1 - 0.03 14.6 0.0 0.03 14.6 0.0 3.8 5 0 0 5 5 3 0 AAA domain DUF258 PF03193.11 EPE31337.1 - 0.044 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EPE31337.1 - 0.064 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EPE31337.1 - 0.066 12.6 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EPE31337.1 - 0.074 12.7 0.0 0.074 12.7 0.0 2.0 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EPE31337.1 - 0.1 12.1 0.1 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_21 PF13304.1 EPE31337.1 - 0.18 11.7 0.2 3.1 7.6 0.0 2.9 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EPE31337.1 - 0.34 11.1 3.8 0.72 10.1 0.0 2.8 3 0 0 3 3 2 0 ABC transporter Pkinase PF00069.20 EPE31339.1 - 5.1e-12 45.4 0.0 6.5e-10 38.5 0.0 3.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE31339.1 - 1.8e-09 37.0 0.0 2.3e-08 33.4 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_1 PF00583.19 EPE31340.1 - 8.4e-07 28.9 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE31340.1 - 4.1e-06 26.8 0.0 6.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE31340.1 - 0.002 17.8 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPE31340.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE31340.1 - 0.041 13.7 0.1 0.15 11.9 0.1 1.9 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase MYT1 PF08474.6 EPE31340.1 - 0.059 12.8 0.7 0.92 8.9 0.2 2.1 2 0 0 2 2 2 0 Myelin transcription factor 1 NOGCT PF08155.6 EPE31341.1 - 4.3e-30 103.1 1.3 9.9e-30 102.0 0.9 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EPE31341.1 - 3.7e-27 93.9 0.9 8.6e-27 92.8 0.6 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EPE31341.1 - 8.4e-15 54.7 0.0 1.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE31341.1 - 1.5e-08 34.0 0.0 2.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EPE31341.1 - 0.00014 22.2 0.0 0.0011 19.4 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EPE31341.1 - 0.0099 15.7 0.1 4.6 7.0 0.0 2.7 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.1 EPE31341.1 - 0.012 15.6 0.4 1.4 8.8 0.1 3.4 2 1 0 2 2 2 0 AAA ATPase domain DUF4192 PF13830.1 EPE31341.1 - 2.2 7.8 7.8 4.7 6.7 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Pribosyltran PF00156.22 EPE31342.1 - 1.4e-13 50.6 0.4 2.9e-13 49.6 0.3 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain BRO1 PF03097.13 EPE31343.1 - 2.6e-132 441.1 0.7 2.6e-132 441.1 0.5 2.6 3 0 0 3 3 3 2 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EPE31343.1 - 1.9e-92 309.4 20.3 3e-92 308.7 14.1 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CTDII PF01556.13 EPE31344.1 - 1e-28 99.0 2.2 2.8e-22 78.3 0.2 3.4 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EPE31344.1 - 7.3e-21 73.6 0.2 7.3e-21 73.6 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EPE31344.1 - 1.3e-09 37.9 22.1 3e-09 36.8 15.3 1.7 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EPE31344.1 - 2.3 7.9 9.5 3.1 7.5 0.9 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Stc1 PF12898.2 EPE31344.1 - 9.8 6.3 8.6 84 3.3 6.0 2.4 1 1 0 1 1 1 0 Stc1 domain SAP30_Sin3_bdg PF13867.1 EPE31345.1 - 2e-11 43.5 0.2 7.7e-10 38.4 0.0 2.8 3 0 0 3 3 3 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Fungal_trans PF04082.13 EPE31347.1 - 1.1e-65 221.1 0.3 1.5e-65 220.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPE31347.1 - 3.9e-05 23.7 10.0 0.00016 21.8 0.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE31347.1 - 0.00035 20.6 13.0 0.00067 19.8 0.7 3.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE31347.1 - 0.67 10.3 11.2 0.76 10.1 0.8 3.1 3 0 0 3 3 3 0 Zinc-finger double domain MIP-T3 PF10243.4 EPE31348.1 - 1.5 7.2 48.5 1.9 6.8 33.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 EPE31348.1 - 2.2 5.9 17.7 2.4 5.7 12.3 1.2 1 0 0 1 1 1 0 Ycf1 DUF4551 PF15087.1 EPE31348.1 - 5.7 5.1 13.2 7.2 4.8 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MCPsignal PF00015.16 EPE31349.1 - 0.01 15.3 2.0 0.017 14.6 1.4 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Orbi_VP5 PF00901.12 EPE31349.1 - 0.018 13.2 1.2 0.031 12.4 0.8 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 zf-C4pol PF14260.1 EPE31349.1 - 0.043 13.8 0.7 0.15 12.0 0.5 1.9 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DUF4158 PF13700.1 EPE31349.1 - 0.061 12.8 0.2 0.17 11.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) zf-tcix PF14952.1 EPE31349.1 - 0.07 12.4 1.6 0.14 11.5 1.1 1.4 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding DUF1664 PF07889.7 EPE31349.1 - 0.18 11.6 4.1 0.34 10.7 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF745 PF05335.8 EPE31349.1 - 0.19 11.2 4.2 0.32 10.4 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) zf-ribbon_3 PF13248.1 EPE31349.1 - 0.2 10.9 0.8 0.34 10.1 0.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-MYND PF01753.13 EPE31351.1 - 0.00037 20.2 13.6 0.0007 19.4 9.5 1.5 1 0 0 1 1 1 1 MYND finger DPM3 PF08285.6 EPE31352.1 - 2.7 7.9 5.7 0.62 9.9 1.5 1.8 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) zf-DHHC PF01529.15 EPE31352.1 - 5.4 6.3 7.2 9.4 5.5 5.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase NACHT PF05729.7 EPE31353.1 - 1.2e-08 34.7 0.0 3.2e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 EPE31353.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 EPE31353.1 - 0.0085 16.1 0.2 0.21 11.5 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPE31353.1 - 0.014 15.4 0.1 0.66 10.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain Abhydrolase_5 PF12695.2 EPE31353.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.9 EPE31355.1 - 8.7e-59 198.9 0.4 1.6e-58 198.1 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EPE31355.1 - 4.4e-11 42.2 10.5 4.4e-11 42.2 7.3 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF218 PF02698.12 EPE31356.1 - 9.7e-09 34.8 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Methyltransf_23 PF13489.1 EPE31357.1 - 9.5e-12 44.9 0.0 3.1e-11 43.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE31357.1 - 2.9e-05 24.4 0.0 7.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE31357.1 - 0.00013 22.3 0.0 0.00049 20.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE31357.1 - 0.00018 21.1 0.0 0.00073 19.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE31357.1 - 0.047 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EPE31358.1 - 3.4e-29 101.7 0.0 6e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EPE31358.1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EPE31358.1 - 0.044 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Glyco_hydro_12 PF01670.11 EPE31359.1 - 1.7e-29 102.6 0.6 1.7e-29 102.6 0.4 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 DUF1455 PF07306.6 EPE31359.1 - 0.013 15.5 4.1 0.025 14.6 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) Sugar_tr PF00083.19 EPE31360.1 - 2e-80 270.5 23.2 2.5e-80 270.2 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE31360.1 - 3.9e-30 104.7 29.4 3.3e-28 98.4 15.1 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE31360.1 - 1.2e-05 23.9 3.5 1.2e-05 23.9 2.4 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein DUF3292 PF11696.3 EPE31361.1 - 1.3e-260 865.8 0.0 1.5e-260 865.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Pex24p PF06398.6 EPE31361.1 - 0.022 13.5 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Flavi_M PF01004.14 EPE31361.1 - 0.14 11.5 0.3 0.31 10.4 0.2 1.5 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M RecA PF00154.16 EPE31362.1 - 5.5e-08 32.2 0.4 8.5e-08 31.6 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EPE31362.1 - 8.8e-06 25.2 0.0 3e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EPE31362.1 - 2e-05 23.7 0.0 3.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 KaiC Rad51 PF08423.6 EPE31362.1 - 0.00056 18.8 0.0 0.82 8.5 0.0 2.8 2 1 0 2 2 2 2 Rad51 NB-ARC PF00931.17 EPE31362.1 - 0.00075 18.4 0.0 0.0011 17.9 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.1 EPE31362.1 - 0.0044 16.6 0.0 0.31 10.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPE31362.1 - 0.006 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE31362.1 - 0.0066 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EPE31362.1 - 0.024 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EPE31362.1 - 0.11 12.3 0.1 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Ribonuclease_T2 PF00445.13 EPE31363.1 - 9.3e-31 106.9 0.0 1.5e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Hap4_Hap_bind PF10297.4 EPE31364.1 - 1.1e-06 28.3 8.7 1.1e-06 28.3 6.0 1.9 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EPE31364.1 - 1.4e-06 28.1 13.0 1.5e-05 24.8 7.9 2.5 1 1 1 2 2 2 1 bZIP transcription factor MAD PF05557.8 EPE31364.1 - 0.0037 15.4 3.9 0.0054 14.8 2.7 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein ACCA PF03255.9 EPE31364.1 - 0.17 11.4 1.2 0.28 10.7 0.8 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF790 PF05626.6 EPE31364.1 - 0.57 8.6 2.6 0.81 8.1 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF790) COG2 PF06148.6 EPE31365.1 - 4.8e-28 97.6 0.0 8e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EPE31365.1 - 0.0002 21.1 0.0 0.00049 19.8 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Sigma70_ner PF04546.8 EPE31365.1 - 0.023 14.2 0.1 0.045 13.3 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EPE31365.1 - 0.21 11.0 2.8 0.39 10.2 1.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_L1 PF00687.16 EPE31366.1 - 3.4e-28 98.5 0.1 5.1e-28 97.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.16 EPE31367.1 - 3.4e-100 334.7 0.0 5e-100 334.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EPE31367.1 - 2.2e-39 134.8 0.2 3.6e-39 134.2 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 EPE31367.1 - 0.0074 15.4 0.7 0.023 13.8 0.2 1.7 1 1 1 2 2 2 1 tRNA synthetases class I (C) catalytic domain Ribosomal_L27 PF01016.14 EPE31368.1 - 2.9e-29 100.6 0.2 4.8e-29 99.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein DNA_methylase PF00145.12 EPE31369.1 - 0.1 11.6 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Kelch_5 PF13854.1 EPE31372.1 - 1.3e-12 47.3 0.5 1.3e-12 47.3 0.4 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 EPE31372.1 - 3.2e-05 23.3 8.6 0.018 14.5 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EPE31372.1 - 3.5e-05 23.8 5.8 0.00015 21.8 0.2 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EPE31372.1 - 0.13 12.5 5.0 0.49 10.6 0.3 3.8 4 1 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 EPE31372.1 - 0.32 10.8 6.9 2.9 7.8 0.4 4.2 4 1 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 EPE31372.1 - 0.63 9.8 12.9 0.55 10.0 0.5 5.4 5 1 0 5 5 5 0 Galactose oxidase, central domain Piwi PF02171.12 EPE31374.1 - 1.5e-53 181.7 0.0 2.3e-53 181.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EPE31374.1 - 3e-05 23.2 0.5 6.4e-05 22.2 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Ank_2 PF12796.2 EPE31375.1 - 3.1e-41 139.5 2.9 8.2e-18 64.5 0.1 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPE31375.1 - 2e-26 90.3 4.3 2.2e-06 27.1 0.0 7.7 7 1 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EPE31375.1 - 2.1e-22 79.0 1.6 9.6e-09 35.5 0.1 5.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE31375.1 - 1.5e-20 72.7 0.7 2.2e-07 30.8 0.0 5.2 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE31375.1 - 2.8e-20 70.3 1.4 0.011 15.9 0.0 8.0 8 0 0 8 8 8 5 Ankyrin repeat NACHT PF05729.7 EPE31375.1 - 0.0097 15.5 0.3 0.032 13.8 0.1 1.9 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.13 EPE31376.1 - 0.021 14.3 0.1 0.067 12.7 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EPE31376.1 - 0.025 14.5 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain NCD2 PF04905.8 EPE31376.1 - 0.066 12.9 0.1 0.092 12.5 0.1 1.1 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) AAA PF00004.24 EPE31376.1 - 0.087 13.0 0.6 0.34 11.1 0.1 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EPE31376.1 - 0.11 12.6 0.2 1.4 9.0 0.0 2.3 2 1 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 EPE31376.1 - 0.14 12.0 0.5 0.61 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain 2OG-FeII_Oxy PF03171.15 EPE31377.1 - 5e-19 68.4 0.0 7.7e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EPE31377.1 - 1.4e-08 35.2 0.0 2.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Methyltransf_2 PF00891.13 EPE31380.1 - 6e-28 97.6 0.0 7.9e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase HTH_24 PF13412.1 EPE31380.1 - 0.0069 15.7 0.2 0.018 14.4 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 EPE31380.1 - 0.0089 16.3 0.1 0.026 14.8 0.0 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain Dimerisation PF08100.6 EPE31380.1 - 1.2 9.0 3.7 1.3 8.8 0.3 2.5 2 0 0 2 2 2 0 Dimerisation domain Chitin_bind_3 PF03067.10 EPE31382.1 - 7.1e-14 52.4 1.4 1.1e-13 51.8 1.0 1.3 1 0 0 1 1 1 1 Chitin binding domain DUF2422 PF10337.4 EPE31383.1 - 4.7e-26 91.5 13.6 8.2e-12 44.6 2.4 3.4 2 1 1 3 3 3 3 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EPE31383.1 - 1.5e-12 47.5 17.7 1.5e-12 47.5 12.3 3.4 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 EPE31383.1 - 3.7e-10 39.0 13.0 3.3e-08 32.6 5.8 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 EPE31383.1 - 2.2e-05 24.1 0.1 4.6e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) Glyco_transf_15 PF01793.11 EPE31384.1 - 3.5e-120 400.9 3.3 4.3e-120 400.6 2.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ist1 PF03398.9 EPE31385.1 - 6.3e-65 217.6 2.5 8.4e-65 217.1 1.7 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF2226 PF09987.4 EPE31385.1 - 0.79 8.7 4.2 0.41 9.7 0.3 1.8 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2226) Acyl-CoA_dh_1 PF00441.19 EPE31386.1 - 8.3e-30 103.8 1.8 1.3e-29 103.2 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EPE31386.1 - 3.1e-19 69.5 0.0 6.3e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EPE31386.1 - 7.8e-17 61.7 1.3 1.8e-16 60.6 0.4 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPE31386.1 - 6.8e-16 57.5 0.1 1.5e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain INCENP_ARK-bind PF03941.10 EPE31387.1 - 6.7e-12 45.0 3.5 3.2e-11 42.8 2.4 2.3 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Pyridox_oxidase PF01243.15 EPE31388.1 - 3.1e-07 30.3 0.0 6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DNA_pol3_tau_4 PF12168.3 EPE31388.1 - 0.16 12.3 1.0 0.24 11.8 0.1 1.6 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding DivIC PF04977.10 EPE31389.1 - 0.088 12.2 1.4 0.58 9.6 0.6 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF3409 PF11889.3 EPE31390.1 - 0.0019 17.8 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3409) Dynactin_p22 PF07426.6 EPE31390.1 - 0.063 12.5 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Dynactin subunit p22 DUF3895 PF13034.1 EPE31391.1 - 0.039 13.4 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) DUF4618 PF15397.1 EPE31392.1 - 0.028 13.7 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) KCNQ_channel PF03520.9 EPE31392.1 - 0.086 12.1 0.2 0.15 11.3 0.1 1.4 1 1 0 1 1 1 0 KCNQ voltage-gated potassium channel RED_C PF07807.6 EPE31392.1 - 0.1 12.7 0.5 0.15 12.2 0.3 1.2 1 0 0 1 1 1 0 RED-like protein C-terminal region adh_short PF00106.20 EPE31394.1 - 3.5e-16 59.5 0.1 1e-14 54.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EPE31394.1 - 6.3e-06 26.3 0.1 1.4e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 EPE31394.1 - 0.00026 20.8 0.1 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE31394.1 - 0.00028 20.6 0.6 0.00077 19.1 0.0 2.0 3 0 0 3 3 3 1 KR domain NmrA PF05368.8 EPE31394.1 - 0.0013 18.0 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EPE31394.1 - 0.033 13.6 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Exo5 PF09810.4 EPE31395.1 - 1.1e-118 396.1 0.0 1.3e-118 395.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EPE31395.1 - 2.3e-08 33.7 0.0 0.0012 18.2 0.0 2.6 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily PAS_9 PF13426.1 EPE31397.1 - 4.6e-17 62.2 0.0 8.4e-15 55.0 0.0 2.9 2 1 0 2 2 2 1 PAS domain RGS PF00615.14 EPE31397.1 - 6e-13 48.9 0.1 1.4e-12 47.7 0.0 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain PAS PF00989.19 EPE31397.1 - 0.00021 21.0 0.0 0.0051 16.5 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EPE31397.1 - 0.0015 18.5 0.0 2.2 8.3 0.0 3.3 4 0 0 4 4 4 2 PAS fold Haem_bd PF14376.1 EPE31398.1 - 0.016 14.8 0.5 0.033 13.8 0.4 1.5 1 0 0 1 1 1 0 Haem-binding domain Bromodomain PF00439.20 EPE31399.1 - 1.2e-20 73.2 0.2 2.9e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 Bromodomain BTB PF00651.26 EPE31399.1 - 0.00071 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF2780 PF11075.3 EPE31399.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) CBM_1 PF00734.13 EPE31401.1 - 1.5e-06 27.7 10.6 1.5e-06 27.7 7.3 2.0 1 1 0 1 1 1 1 Fungal cellulose binding domain Abhydrolase_1 PF00561.15 EPE31402.1 - 8.9e-14 51.6 0.0 1.3e-13 51.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EPE31402.1 - 1.5e-13 50.4 0.0 3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EPE31402.1 - 3e-10 40.3 0.0 8.9e-10 38.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE31402.1 - 0.024 14.3 0.0 0.2 11.4 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyco_transf_22 PF03901.12 EPE31404.1 - 5.6e-88 295.7 19.4 6.5e-88 295.5 13.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.9 EPE31405.1 - 2.8e-46 156.8 1.5 2.8e-46 156.8 1.0 2.6 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region DUF3445 PF11927.3 EPE31406.1 - 2.9e-78 262.7 0.0 3.8e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) HAUS-augmin3 PF14932.1 EPE31407.1 - 0.2 10.7 8.5 0.39 9.8 5.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 BIR PF00653.16 EPE31408.1 - 4.4e-42 142.3 8.6 1.6e-21 76.4 0.1 2.3 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Rsm1 PF08600.5 EPE31408.1 - 0.00045 20.0 2.4 0.0022 17.7 0.0 2.7 2 1 0 2 2 2 1 Rsm1-like zf-C3HC PF07967.8 EPE31408.1 - 0.028 14.1 7.0 0.071 12.8 2.6 2.7 2 1 1 3 3 3 0 C3HC zinc finger-like zf-RING_3 PF14369.1 EPE31408.1 - 0.04 13.9 0.9 11 6.1 0.1 2.6 2 0 0 2 2 2 0 zinc-finger ARA70 PF12489.3 EPE31408.1 - 0.072 13.0 0.3 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 Nuclear coactivator DUF4360 PF14273.1 EPE31409.1 - 1.2e-57 194.5 0.9 1.4e-57 194.2 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF2673 PF10880.3 EPE31409.1 - 4.2 7.4 8.3 6.1 6.9 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2673) Pkinase PF00069.20 EPE31410.1 - 2.5e-42 144.8 0.0 3.4e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE31410.1 - 5.7e-21 74.7 0.0 8.3e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPE31410.1 - 0.0084 15.8 0.0 2.8 7.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family muHD PF10291.4 EPE31411.1 - 3.7e-65 219.6 0.0 5.5e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EPE31411.1 - 2.1e-11 43.8 0.0 6.5e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain CAP_N PF01213.14 EPE31411.1 - 0.013 14.8 0.1 0.013 14.8 0.1 3.3 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal MAD PF05557.8 EPE31412.1 - 1.6e-51 175.3 58.1 2.1e-51 174.9 40.3 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Fib_alpha PF08702.5 EPE31412.1 - 0.019 15.0 0.3 0.019 15.0 0.2 6.0 4 2 1 6 6 6 0 Fibrinogen alpha/beta chain family Mmp37 PF09139.6 EPE31413.1 - 3.1e-41 141.5 0.0 3.5e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 ABC_membrane PF00664.18 EPE31414.1 - 2.2e-80 269.9 45.2 4.2e-42 144.4 8.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region p450 PF00067.17 EPE31414.1 - 9.2e-63 212.3 0.0 1.4e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.22 EPE31414.1 - 4e-59 198.8 0.0 2.6e-32 112.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPE31414.1 - 4.7e-12 45.5 4.7 0.00036 19.8 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE31414.1 - 1.8e-09 38.0 0.4 0.00055 19.9 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPE31414.1 - 1.3e-08 34.2 0.9 0.0008 18.8 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EPE31414.1 - 1.7e-07 31.4 0.6 0.0039 17.1 0.2 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EPE31414.1 - 6e-07 30.3 0.0 0.0057 17.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EPE31414.1 - 8.4e-07 27.9 2.4 0.0066 15.0 0.1 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EPE31414.1 - 8.9e-07 28.2 0.1 0.035 13.2 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EPE31414.1 - 6.4e-05 23.3 0.1 0.061 13.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EPE31414.1 - 0.0001 22.1 1.9 0.57 10.1 0.2 3.8 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EPE31414.1 - 0.00066 19.3 0.1 0.64 9.5 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EPE31414.1 - 0.0012 18.5 0.1 0.95 9.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EPE31414.1 - 0.0012 19.1 0.0 0.32 11.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EPE31414.1 - 0.0013 18.3 0.0 0.2 11.1 0.0 3.6 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.1 EPE31414.1 - 0.0028 17.8 2.7 2.1 8.4 0.1 3.5 2 2 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPE31414.1 - 0.014 14.7 1.1 2.3 7.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain YebG PF07130.7 EPE31414.1 - 0.017 14.8 0.0 8.1 6.2 0.0 3.2 3 0 0 3 3 3 0 YebG protein G-alpha PF00503.15 EPE31414.1 - 0.017 13.8 0.0 1.2 7.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.12 EPE31414.1 - 0.032 14.0 0.2 4.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EPE31414.1 - 0.037 13.4 0.2 12 5.2 0.1 3.1 3 0 0 3 3 3 0 AAA-like domain AAA_33 PF13671.1 EPE31414.1 - 0.079 12.8 0.0 16 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EPE31414.1 - 0.085 11.9 0.7 1.7 7.6 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_28 PF13521.1 EPE31414.1 - 0.1 12.5 0.3 0.84 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EPE31414.1 - 0.14 11.1 0.0 2 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 EPE31414.1 - 0.17 11.8 0.7 14 5.6 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 EPE31414.1 - 0.28 10.8 1.9 12 5.4 0.0 3.2 3 0 0 3 3 3 0 NACHT domain DUF4191 PF13829.1 EPE31414.1 - 0.54 9.3 2.5 1.6 7.7 1.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Aldose_epim PF01263.15 EPE31415.1 - 2.7e-30 105.5 0.1 3.4e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase ADH_zinc_N PF00107.21 EPE31417.1 - 6.2e-11 41.9 0.1 1.5e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE31417.1 - 0.00035 20.3 0.1 0.00067 19.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain S1 PF00575.18 EPE31417.1 - 0.019 15.0 0.0 0.23 11.5 0.0 2.4 3 0 0 3 3 3 0 S1 RNA binding domain AMP-binding PF00501.23 EPE31418.1 - 1.7e-79 267.1 0.0 2.9e-79 266.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EPE31418.1 - 3.2e-56 190.6 0.0 8.4e-56 189.2 0.0 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPE31418.1 - 1.9e-52 178.5 0.0 3.6e-52 177.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EPE31418.1 - 6.1e-46 156.3 0.6 1.2e-45 155.3 0.4 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EPE31418.1 - 6.8e-45 153.4 0.0 1.2e-44 152.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EPE31418.1 - 1.2e-42 145.7 0.0 2.6e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 EPE31418.1 - 1.1e-40 139.2 0.6 1.4e-39 135.6 0.1 2.9 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPE31418.1 - 1.5e-21 76.4 0.3 4.7e-21 74.8 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EPE31418.1 - 3.9e-17 62.5 0.0 1e-16 61.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EPE31418.1 - 2.8e-14 53.1 10.6 1.4e-08 34.8 0.1 4.0 4 0 0 4 4 3 2 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EPE31418.1 - 4.9e-13 49.3 0.0 6.4e-11 42.5 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE31418.1 - 9.6e-13 48.1 0.0 1.5e-11 44.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE31418.1 - 3.5e-11 42.9 0.0 2.8e-10 39.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE31418.1 - 1.7e-07 31.7 0.0 6.4e-07 29.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EPE31418.1 - 5.9e-06 26.5 0.0 1.7e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain Ubie_methyltran PF01209.13 EPE31418.1 - 0.00013 21.1 0.0 0.00029 20.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EPE31418.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 EPE31418.1 - 0.084 11.8 0.0 0.23 10.4 0.0 1.7 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Zn_clus PF00172.13 EPE31419.1 - 9.5e-08 31.8 7.0 1.7e-07 31.0 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1415 PF07209.7 EPE31419.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1415) Ank_2 PF12796.2 EPE31420.1 - 1.4e-06 28.5 0.0 9.9e-05 22.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE31420.1 - 4e-05 23.2 1.1 0.0014 18.3 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 EPE31420.1 - 0.00063 20.1 0.3 0.092 13.2 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE31420.1 - 0.0017 18.3 0.2 0.12 12.7 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat PRKCSH-like PF12999.2 EPE31420.1 - 0.093 12.3 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Glucosidase II beta subunit-like TP_methylase PF00590.15 EPE31423.1 - 3e-19 69.5 0.1 7.1e-19 68.3 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.3 EPE31424.1 - 4.9e-06 26.5 0.1 8.2e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPE31424.1 - 3.4e-05 23.8 0.3 6.1e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 EPE31424.1 - 0.00016 21.4 5.7 0.00016 21.4 3.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) DUF4398 PF14346.1 EPE31424.1 - 4.9 7.2 15.6 7.8 6.6 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Crystall PF00030.14 EPE31425.1 - 0.13 12.1 1.3 0.34 10.8 0.8 1.8 1 1 1 2 2 2 0 Beta/Gamma crystallin Aminotran_1_2 PF00155.16 EPE31427.1 - 3e-62 210.6 0.0 3.5e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 EPE31427.1 - 0.16 10.5 0.0 0.26 9.8 0.0 1.3 1 0 0 1 1 1 0 Allinase zf-CCHC_2 PF13696.1 EPE31429.1 - 0.0092 15.4 2.5 0.024 14.1 1.7 1.8 1 0 0 1 1 1 1 Zinc knuckle Epimerase PF01370.16 EPE31430.1 - 5.3e-17 62.0 0.0 6.8e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPE31430.1 - 9.9e-09 34.4 0.0 1.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EPE31430.1 - 4.6e-06 25.5 0.0 1.9e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPE31430.1 - 7.3e-05 22.8 0.0 0.0002 21.4 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPE31430.1 - 0.0012 18.7 0.1 0.0034 17.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase EphA2_TM PF14575.1 EPE31431.1 - 0.0066 16.8 0.1 0.42 11.0 0.0 2.1 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.2 EPE31431.1 - 0.0067 15.6 0.0 0.0067 15.6 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity CMD PF02627.15 EPE31432.1 - 8.4e-07 28.7 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family SAP30_Sin3_bdg PF13867.1 EPE31432.1 - 0.12 12.3 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DAO PF01266.19 EPE31433.1 - 4.3e-24 85.1 0.1 5.2e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE31433.1 - 9.9e-05 22.2 0.1 0.0003 20.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPE31433.1 - 0.0001 21.4 0.0 0.00033 19.8 0.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EPE31433.1 - 0.021 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EPE31433.1 - 0.028 13.0 0.1 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EPE31433.1 - 0.028 14.2 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPE31433.1 - 0.056 12.4 0.1 0.087 11.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EPE31433.1 - 0.074 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EHN PF06441.7 EPE31434.1 - 1.1e-31 109.0 2.1 1.9e-31 108.2 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EPE31434.1 - 3.6e-12 46.6 0.0 5.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE31434.1 - 2.1e-07 30.7 0.0 1.2e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF336 PF03928.9 EPE31435.1 - 9.5e-33 112.8 2.7 1.1e-32 112.6 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Glyco_trans_1_4 PF13692.1 EPE31436.1 - 2.3e-26 92.5 0.0 1.4e-25 89.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Cation_efflux PF01545.16 EPE31437.1 - 1.3e-58 198.3 0.8 1.8e-58 197.8 0.5 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EPE31437.1 - 0.00068 18.7 67.8 0.045 12.7 18.4 4.2 2 2 0 2 2 2 2 ZIP Zinc transporter UQ_con PF00179.21 EPE31441.1 - 4e-34 117.0 0.0 5.1e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPE31441.1 - 0.0046 16.7 0.1 0.0092 15.7 0.1 1.7 1 1 0 1 1 1 1 Prokaryotic E2 family B HD PF01966.17 EPE31443.1 - 5.2e-07 29.7 0.1 6.9e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 HD domain ER-remodelling PF14755.1 EPE31444.1 - 6.5 6.8 7.4 11 6.0 0.3 2.7 2 1 0 2 2 2 0 Intracellular membrane remodeller Cmc1 PF08583.5 EPE31447.1 - 0.096 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like O-FucT PF10250.4 EPE31448.1 - 0.0008 18.6 0.0 0.013 14.5 0.0 2.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF4521 PF15021.1 EPE31449.1 - 0.021 14.3 1.7 0.023 14.3 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) GATase PF00117.23 EPE31450.1 - 9.9e-07 28.3 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EPE31450.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Med4 PF10018.4 EPE31451.1 - 1.9e-38 131.7 6.8 2.5e-38 131.3 4.7 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DivIVA PF05103.8 EPE31451.1 - 4 7.5 9.2 0.66 10.0 0.9 2.6 2 1 0 2 2 2 0 DivIVA protein Hemerythrin PF01814.18 EPE31452.1 - 6e-07 29.6 1.3 9e-07 29.1 0.9 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain EF-hand_1 PF00036.27 EPE31453.1 - 1.9e-24 83.0 13.4 3.8e-08 32.0 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EPE31453.1 - 1.5e-23 80.4 4.1 7.1e-06 25.4 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 EPE31453.1 - 5.9e-22 77.5 3.3 1.6e-13 50.5 0.2 3.1 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPE31453.1 - 4.5e-17 60.5 14.2 2.6e-05 23.3 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EPE31453.1 - 2.8e-14 52.4 13.6 1.8e-05 24.2 0.9 4.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EPE31453.1 - 1.2e-09 37.7 7.5 0.0018 17.9 0.1 4.0 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EPE31453.1 - 3e-05 23.8 0.5 0.019 14.8 0.0 3.2 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EPE31453.1 - 0.0012 18.8 1.7 0.41 10.6 0.1 3.0 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EPE31453.1 - 0.0039 16.8 3.2 0.33 10.6 0.1 3.8 4 0 0 4 4 4 1 EF hand DUF1679 PF07914.6 EPE31453.1 - 0.0047 15.6 0.9 0.17 10.4 0.1 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF1679) Toprim PF01751.17 EPE31453.1 - 0.033 14.1 0.0 11 6.0 0.0 2.3 1 1 0 2 2 2 0 Toprim domain EF-hand_2 PF09068.6 EPE31453.1 - 0.049 13.7 0.1 2.9 7.9 0.0 2.8 3 1 0 3 3 3 0 EF hand Mad3_BUB1_II PF08171.6 EPE31453.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 LigB PF02900.13 EPE31454.1 - 4.9e-47 160.1 0.0 5.8e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short PF00106.20 EPE31456.1 - 9.3e-23 80.9 2.2 1e-21 77.6 1.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE31456.1 - 1.5e-18 67.4 4.6 1.2e-17 64.5 3.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE31456.1 - 1.1e-08 34.9 0.5 1.1e-08 34.9 0.4 1.6 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EPE31456.1 - 0.0004 20.4 2.2 0.0024 17.9 1.6 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EPE31456.1 - 0.00052 19.5 2.0 0.0034 16.8 0.8 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EPE31456.1 - 0.033 13.7 0.8 0.068 12.7 0.6 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 EPE31456.1 - 0.041 13.6 0.2 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 EPE31456.1 - 0.059 13.6 0.5 0.14 12.4 0.2 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EPE31456.1 - 0.13 12.2 2.8 3.1 7.7 2.0 2.7 1 1 0 1 1 1 0 NADH(P)-binding Pyr_redox_3 PF13738.1 EPE31459.1 - 1e-18 68.1 0.1 3.1e-18 66.5 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE31459.1 - 1.5e-15 56.3 0.0 1.3e-14 53.3 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPE31459.1 - 1.1e-09 37.6 0.2 3.7e-07 29.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPE31459.1 - 2.6e-09 37.2 0.0 2.7e-08 33.9 0.0 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE31459.1 - 2.1e-08 34.0 1.2 1.4e-07 31.4 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPE31459.1 - 2.4e-07 31.0 2.0 0.017 15.5 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE31459.1 - 3.6e-05 22.8 0.0 0.00012 21.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EPE31459.1 - 0.00023 21.2 0.2 0.12 12.5 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EPE31459.1 - 0.0021 17.8 1.4 0.02 14.6 0.1 2.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EPE31459.1 - 0.0034 17.0 0.2 0.0055 16.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EPE31459.1 - 0.0091 14.4 1.0 0.15 10.4 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.2 EPE31459.1 - 0.044 12.8 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EPE31459.1 - 0.052 12.7 0.0 8.8 5.4 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EPE31459.1 - 0.096 11.5 3.0 0.049 12.4 0.6 1.6 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EPE31459.1 - 0.17 10.7 0.1 0.38 9.6 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EPE31459.1 - 0.18 11.3 0.5 2.1 7.9 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EPE31459.1 - 0.35 9.9 1.2 1.6 7.7 0.1 2.2 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.17 EPE31459.1 - 4.6 5.9 6.4 0.2 10.4 0.5 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A EMP70 PF02990.11 EPE31461.1 - 4.9e-200 665.4 3.6 6.7e-200 664.9 2.5 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 EPE31461.1 - 0.0039 17.3 0.0 0.0039 17.3 0.0 4.7 2 2 3 5 5 5 1 NfeD-like C-terminal, partner-binding PIRT PF15099.1 EPE31461.1 - 3.6 6.8 6.7 0.64 9.2 1.6 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Sas10_Utp3 PF04000.10 EPE31462.1 - 2.7e-16 59.5 1.8 6.4e-16 58.3 1.2 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family PLRV_ORF5 PF01690.12 EPE31462.1 - 0.85 8.6 13.3 1.1 8.2 9.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mito_carr PF00153.22 EPE31463.1 - 4.8e-61 202.5 4.7 1e-20 73.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PBP-Tp47_a PF14889.1 EPE31463.1 - 0.035 13.4 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Pkinase PF00069.20 EPE31464.1 - 3.9e-05 22.9 0.0 6.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain His_Phos_1 PF00300.17 EPE31464.1 - 0.06 13.4 0.1 0.95 9.5 0.0 2.5 2 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) DUF1664 PF07889.7 EPE31465.1 - 0.13 12.0 26.3 0.19 11.5 0.0 6.7 4 2 2 8 8 8 0 Protein of unknown function (DUF1664) Mnd1 PF03962.10 EPE31465.1 - 0.99 9.0 8.3 0.6 9.7 0.0 4.2 3 1 0 3 3 3 0 Mnd1 family CorA PF01544.13 EPE31466.1 - 7e-11 41.7 0.3 1.5e-10 40.5 0.2 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein IncA PF04156.9 EPE31466.1 - 0.2 11.2 0.5 0.44 10.1 0.1 1.7 2 0 0 2 2 2 0 IncA protein ABC2_membrane PF01061.19 EPE31466.1 - 0.36 9.9 6.3 0.55 9.3 4.3 1.2 1 0 0 1 1 1 0 ABC-2 type transporter Cep57_CLD_2 PF14197.1 EPE31466.1 - 4.2 7.3 5.5 5.5 7.0 0.2 2.9 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 His_Phos_1 PF00300.17 EPE31467.1 - 2.2e-08 34.3 0.0 2.1e-06 27.9 0.0 2.6 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Peptidase_C13 PF01650.13 EPE31468.1 - 1.8e-41 142.1 0.1 2.5e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Serinc PF03348.10 EPE31469.1 - 1.9e-176 587.0 7.1 2.3e-176 586.7 4.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) ATG27 PF09451.5 EPE31469.1 - 1.7 7.8 3.8 0.33 10.1 0.1 1.6 2 0 0 2 2 2 0 Autophagy-related protein 27 MFS_1 PF07690.11 EPE31470.1 - 7.7e-16 57.7 30.9 4.7e-15 55.1 20.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EPE31470.1 - 4.3e-14 52.3 3.5 4.3e-14 52.3 2.5 1.7 2 0 0 2 2 2 1 Nodulin-like DUF3611 PF12263.3 EPE31470.1 - 0.15 11.4 3.0 8.6 5.7 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3611) ABC2_membrane_2 PF12679.2 EPE31470.1 - 1.2 7.9 9.0 6.2 5.6 3.3 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein PGAP1 PF07819.8 EPE31471.1 - 2.1e-87 292.4 0.0 3.5e-87 291.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPE31471.1 - 1.4e-05 24.9 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE31471.1 - 0.0003 20.7 0.1 0.00061 19.7 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE31471.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF601 PF04642.7 EPE31471.1 - 0.037 13.4 4.1 0.02 14.2 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF601 DUF676 PF05057.9 EPE31471.1 - 0.037 13.3 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) COesterase PF00135.23 EPE31471.1 - 0.065 11.9 0.0 0.097 11.3 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family adh_short_C2 PF13561.1 EPE31472.1 - 7.9e-33 114.2 0.0 9.6e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE31472.1 - 1.6e-28 99.7 0.0 1.9e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE31472.1 - 7e-07 29.0 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE31472.1 - 8.3e-05 22.1 0.1 0.0004 19.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE31472.1 - 0.03 14.3 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding AAA PF00004.24 EPE31473.1 - 2.1e-37 128.2 0.0 5.1e-37 127.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EPE31473.1 - 2.7e-06 27.2 0.0 7.6e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPE31473.1 - 4.9e-06 26.6 0.2 0.00055 19.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EPE31473.1 - 2.5e-05 25.0 0.0 6.6e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPE31473.1 - 2.7e-05 24.3 0.1 0.00042 20.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPE31473.1 - 4.1e-05 23.3 0.2 0.00047 19.8 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPE31473.1 - 5.7e-05 23.0 0.0 0.00018 21.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EPE31473.1 - 6.3e-05 22.1 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EPE31473.1 - 0.0002 20.8 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EPE31473.1 - 0.00034 20.5 0.0 0.00068 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EPE31473.1 - 0.00037 20.1 0.2 0.01 15.5 0.0 2.5 2 1 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 EPE31473.1 - 0.00041 19.7 0.2 0.039 13.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EPE31473.1 - 0.00042 20.3 0.0 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EPE31473.1 - 0.00081 18.6 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EPE31473.1 - 0.0012 18.9 0.0 0.0037 17.4 0.0 1.9 2 0 0 2 2 1 1 RNA helicase Zeta_toxin PF06414.7 EPE31473.1 - 0.0037 16.3 0.0 0.0071 15.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EPE31473.1 - 0.0039 17.1 0.0 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE31473.1 - 0.0049 16.5 0.0 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_24 PF13479.1 EPE31473.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EPE31473.1 - 0.0073 15.7 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 EPE31473.1 - 0.0078 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 EPE31473.1 - 0.014 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 EPE31473.1 - 0.016 15.4 0.0 0.044 14.0 0.0 1.9 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.8 EPE31473.1 - 0.024 13.5 0.4 0.084 11.7 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_11 PF13086.1 EPE31473.1 - 0.026 14.0 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 EPE31473.1 - 0.029 13.8 0.0 0.84 9.0 0.0 2.8 2 1 1 3 3 3 0 Guanylate kinase CPT PF07931.7 EPE31473.1 - 0.037 13.6 0.1 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.10 EPE31473.1 - 0.047 12.3 0.0 0.07 11.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 EPE31473.1 - 0.051 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EPE31473.1 - 0.067 12.8 0.0 0.24 11.0 0.0 1.8 1 1 1 2 2 2 0 Archaeal ATPase KaiC PF06745.8 EPE31473.1 - 0.09 11.8 0.0 1.2 8.1 0.0 2.3 1 1 1 2 2 2 0 KaiC NB-ARC PF00931.17 EPE31473.1 - 0.094 11.5 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain SKI PF01202.17 EPE31473.1 - 0.095 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase UPF0079 PF02367.12 EPE31473.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CH PF00307.26 EPE31474.1 - 4.7e-38 129.5 0.4 3.1e-19 69.0 0.1 2.9 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EPE31474.1 - 7.4e-27 93.1 0.3 2e-25 88.5 0.0 2.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EPE31474.1 - 2.9e-12 46.0 0.2 3.7e-08 32.9 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.1 EPE31474.1 - 0.00062 19.4 0.2 0.0075 16.0 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 EPE31474.1 - 0.018 14.6 0.5 0.43 10.2 0.0 3.3 3 1 1 4 4 4 0 EF-hand domain pair EIAV_Rev PF11129.3 EPE31474.1 - 0.021 14.8 2.1 0.071 13.1 1.4 1.8 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus EF-hand_1 PF00036.27 EPE31474.1 - 0.028 13.7 0.3 0.35 10.2 0.0 2.9 3 0 0 3 3 3 0 EF hand Spectrin PF00435.16 EPE31474.1 - 0.06 13.6 3.2 2.2 8.6 0.1 2.7 2 0 0 2 2 2 0 Spectrin repeat EF-hand_7 PF13499.1 EPE31474.1 - 0.53 10.4 3.2 0.82 9.8 1.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Dynamin_N PF00350.18 EPE31475.1 - 6.8e-30 104.0 0.1 1.8e-29 102.7 0.1 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EPE31475.1 - 9.9e-17 60.6 0.1 8.2e-16 57.6 0.0 2.2 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EPE31475.1 - 5.4e-05 23.1 0.3 0.0007 19.5 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase CheZ PF04344.8 EPE31475.1 - 0.0035 17.0 0.0 0.039 13.6 0.0 2.6 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ GED PF02212.13 EPE31475.1 - 0.011 15.5 0.5 0.011 15.5 0.4 2.7 3 0 0 3 3 3 0 Dynamin GTPase effector domain Miro PF08477.8 EPE31475.1 - 0.015 15.8 0.1 0.14 12.6 0.1 2.6 1 1 0 1 1 1 0 Miro-like protein AAA_21 PF13304.1 EPE31475.1 - 0.046 13.6 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2478 PF10649.4 EPE31475.1 - 0.049 12.9 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) Peptidase_M75 PF09375.5 EPE31475.1 - 0.068 12.4 1.5 0.089 12.0 0.1 1.9 2 0 0 2 2 2 0 Imelysin AAA_29 PF13555.1 EPE31475.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Methyltransf_11 PF08241.7 EPE31479.1 - 9.3e-10 38.8 0.0 1.6e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE31479.1 - 1.2e-06 28.8 0.0 2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE31479.1 - 5.3e-06 26.1 0.0 7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE31479.1 - 1e-05 26.0 0.0 2.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE31479.1 - 2.3e-05 24.1 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE31479.1 - 3.8e-05 24.0 0.0 6.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Myb_DNA-binding PF00249.26 EPE31480.1 - 2.8e-11 43.2 4.7 5.2e-09 36.0 0.2 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPE31480.1 - 2.2e-07 30.8 4.2 0.00022 21.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Sporozoite_P67 PF05642.6 EPE31480.1 - 0.11 10.2 1.3 0.16 9.8 0.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ubiquitin_2 PF14560.1 EPE31482.1 - 1.4e-17 63.7 0.0 2.3e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EPE31482.1 - 8.8e-05 21.8 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family CAP_GLY PF01302.20 EPE31483.1 - 3e-20 71.6 2.9 4e-20 71.2 2.0 1.2 1 0 0 1 1 1 1 CAP-Gly domain DUF726 PF05277.7 EPE31484.1 - 4.7e-111 371.0 0.8 7.1e-111 370.4 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 EPE31484.1 - 0.00013 22.2 0.0 0.00042 20.6 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EPE31484.1 - 0.00019 21.4 0.5 0.00051 19.9 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE31484.1 - 0.0042 16.8 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EPE31484.1 - 0.021 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Cutinase Transp_cyt_pur PF02133.10 EPE31485.1 - 1.8e-106 356.3 38.0 2.2e-106 356.0 26.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin S1FA PF04689.8 EPE31485.1 - 0.071 13.0 0.5 0.29 11.0 0.2 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA AMP-binding PF00501.23 EPE31486.1 - 3.2e-27 94.9 0.0 1.3e-26 92.9 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPE31486.1 - 8e-22 77.3 0.0 1.4e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EPE31486.1 - 4.4e-10 39.6 0.0 1.3e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EPE31486.1 - 0.00016 21.1 0.0 0.00043 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EPE31486.1 - 0.007 16.2 0.4 0.078 12.8 0.2 2.6 1 1 0 1 1 1 1 short chain dehydrogenase DXP_reductoisom PF02670.11 EPE31486.1 - 0.024 15.1 0.1 0.069 13.6 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.19 EPE31486.1 - 0.028 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EPE31486.1 - 0.057 13.0 0.3 1.5 8.4 0.2 2.7 1 1 0 1 1 1 0 KR domain zf-RING_2 PF13639.1 EPE31487.1 - 3.8e-14 52.2 4.4 5.9e-14 51.6 3.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPE31487.1 - 3.6e-08 33.3 0.1 6e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPE31487.1 - 7.7e-07 28.6 3.6 1.2e-06 28.0 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE31487.1 - 1.9e-06 27.7 4.7 3e-06 27.1 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE31487.1 - 7.9e-06 25.4 3.0 1.2e-05 24.8 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE31487.1 - 2.9e-05 23.6 1.2 4.8e-05 22.9 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SpoIIIAH PF12685.2 EPE31487.1 - 0.0015 18.0 0.0 0.0082 15.6 0.0 2.2 1 1 0 1 1 1 1 SpoIIIAH-like protein zf-Apc11 PF12861.2 EPE31487.1 - 0.0025 17.6 0.5 0.0045 16.7 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EPE31487.1 - 0.0076 15.8 2.7 0.013 15.1 1.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EPE31487.1 - 0.074 13.0 2.5 0.12 12.4 1.7 1.3 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 EPE31487.1 - 0.076 12.9 2.6 0.78 9.7 1.8 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EPE31487.1 - 0.57 9.9 3.3 1.1 9.0 2.3 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EPE31487.1 - 0.59 9.9 4.3 6 6.6 3.3 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF1191 PF06697.7 EPE31488.1 - 0.012 14.4 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF2283 PF10049.4 EPE31489.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) Ras PF00071.17 EPE31490.1 - 1.3e-65 219.7 0.5 1.5e-65 219.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE31490.1 - 1.1e-21 77.5 0.0 1.7e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE31490.1 - 2.4e-16 59.4 0.1 2.9e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPE31490.1 - 2.1e-05 23.8 0.1 2.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPE31490.1 - 2.9e-05 23.5 0.1 6.1e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPE31490.1 - 6e-05 22.9 0.1 9.3e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPE31490.1 - 0.00038 19.7 0.0 0.00055 19.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 EPE31490.1 - 0.00049 20.2 0.1 0.094 12.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE31490.1 - 0.0013 18.9 0.0 0.0025 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EPE31490.1 - 0.003 16.8 0.0 0.02 14.1 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EPE31490.1 - 0.0089 15.2 0.0 0.024 13.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPE31490.1 - 0.016 15.2 0.1 0.064 13.2 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EPE31490.1 - 0.021 14.6 0.2 0.067 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPE31490.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EPE31490.1 - 0.047 13.4 0.1 0.096 12.4 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EPE31490.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 EPE31490.1 - 0.08 11.9 0.0 0.2 10.6 0.0 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 EPE31490.1 - 0.091 12.2 0.0 0.93 8.9 0.0 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.27 EPE31492.1 - 9.1e-16 57.0 19.7 0.0054 16.5 0.4 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EPE31492.1 - 0.002 18.3 0.2 0.31 11.3 0.0 3.9 4 0 0 4 4 4 1 PQQ-like domain DUF1647 PF07801.6 EPE31492.1 - 0.045 13.2 0.2 0.078 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) WD40 PF00400.27 EPE31493.1 - 5.5e-21 73.6 5.2 5.3e-05 22.9 0.0 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 EPE31493.1 - 8.3e-11 41.6 0.6 3.1e-10 39.8 0.4 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 EPE31493.1 - 4.7e-08 32.2 0.0 1e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.6 EPE31493.1 - 7e-05 22.6 0.8 0.0036 17.0 0.1 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.3 EPE31493.1 - 0.099 12.4 2.4 0.23 11.3 1.7 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal IKI3 PF04762.7 EPE31493.1 - 0.14 9.9 0.1 0.43 8.3 0.0 1.7 1 1 1 2 2 2 0 IKI3 family DUF4083 PF13314.1 EPE31494.1 - 2 8.2 7.1 0.76 9.6 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4083) Beta_elim_lyase PF01212.16 EPE31495.1 - 4.6e-70 236.0 0.0 6e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EPE31495.1 - 0.0015 16.8 0.0 0.0026 16.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPE31495.1 - 0.014 14.3 0.0 0.025 13.5 0.0 1.4 2 0 0 2 2 2 0 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EPE31495.1 - 0.067 12.2 0.1 0.24 10.3 0.0 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family adh_short PF00106.20 EPE31496.1 - 2.2e-31 109.0 1.1 2.7e-31 108.7 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE31496.1 - 2.3e-21 76.6 0.2 2.8e-21 76.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE31496.1 - 3.5e-10 39.8 0.3 5e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.1 EPE31496.1 - 0.0002 21.4 0.4 0.068 13.3 0.3 2.9 1 1 0 1 1 1 1 Helix-hairpin-helix domain Epimerase PF01370.16 EPE31496.1 - 0.0038 16.6 0.2 0.0078 15.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4360 PF14273.1 EPE31497.1 - 1.2e-28 100.0 1.1 1.5e-28 99.7 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SSP160 PF06933.6 EPE31499.1 - 0.37 8.7 6.0 0.49 8.3 4.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 GIT_SHD PF08518.6 EPE31501.1 - 4.4e-20 70.7 9.4 1e-13 50.3 0.5 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT HeLo PF14479.1 EPE31501.1 - 3.9e-18 65.9 1.0 3.9e-18 65.9 0.7 1.7 2 0 0 2 2 2 1 Prion-inhibition and propagation RA PF00788.18 EPE31501.1 - 3.6e-16 59.4 0.0 6.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain TUG-UBL1 PF11470.3 EPE31501.1 - 0.024 14.5 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 GLUT4 regulating protein TUG SnoaL_2 PF12680.2 EPE31503.1 - 0.012 16.0 0.0 0.039 14.3 0.0 1.9 2 0 0 2 2 2 0 SnoaL-like domain adh_short PF00106.20 EPE31504.1 - 3e-18 66.2 1.2 8.1e-18 64.8 0.8 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE31504.1 - 7.8e-10 38.7 0.2 9.6e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EPE31504.1 - 4.2e-06 25.8 0.0 6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EPE31504.1 - 0.00019 20.4 0.1 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EPE31504.1 - 0.0013 18.7 0.1 0.019 14.9 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EPE31504.1 - 0.0082 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Glyco_transf_28 PF03033.15 EPE31505.1 - 2.4e-22 79.1 0.0 7.6e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EPE31505.1 - 1.4e-07 30.5 0.0 2.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase AAA PF00004.24 EPE31508.1 - 2e-51 173.6 0.0 3.9e-43 146.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE31508.1 - 1.8e-06 28.7 0.0 0.0013 19.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPE31508.1 - 1.4e-05 24.5 0.2 0.00076 18.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPE31508.1 - 0.00014 21.0 0.0 0.00047 19.2 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 EPE31508.1 - 0.00044 19.2 0.0 0.00076 18.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 EPE31508.1 - 0.00064 19.8 0.0 0.0063 16.6 0.0 2.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPE31508.1 - 0.001 19.2 0.0 0.013 15.7 0.0 2.4 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 EPE31508.1 - 0.0013 18.2 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EPE31508.1 - 0.0014 18.6 2.4 0.026 14.5 0.0 3.3 3 1 1 4 4 3 1 AAA ATPase domain AAA_2 PF07724.9 EPE31508.1 - 0.0018 18.2 0.0 0.0073 16.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EPE31508.1 - 0.004 15.9 0.0 0.0087 14.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EPE31508.1 - 0.0042 16.7 0.0 0.026 14.2 0.0 2.4 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EPE31508.1 - 0.013 14.6 0.4 0.04 13.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EPE31508.1 - 0.014 15.2 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EPE31508.1 - 0.02 14.6 0.0 0.073 12.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EPE31508.1 - 0.021 14.7 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EPE31508.1 - 0.033 13.3 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 EPE31508.1 - 0.035 14.4 0.0 0.092 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EPE31508.1 - 0.042 12.9 0.0 0.55 9.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.11 EPE31508.1 - 0.043 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 EPE31508.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1956 PF09209.6 EPE31508.1 - 0.11 12.3 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1956) PPV_E1_C PF00519.12 EPE31508.1 - 0.19 10.3 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Abhydro_lipase PF04083.11 EPE31509.1 - 1e-15 56.8 0.0 1.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EPE31509.1 - 9.3e-08 32.2 0.2 1.9e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE31509.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE31509.1 - 0.031 13.8 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-RING_2 PF13639.1 EPE31510.1 - 1.3e-11 44.1 3.8 1.3e-11 44.1 2.6 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EPE31510.1 - 2.9e-08 33.2 1.7 2.9e-08 33.2 1.2 2.4 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EPE31510.1 - 1.3e-07 31.5 2.6 1.3e-07 31.5 1.8 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE31510.1 - 3.5e-07 29.7 3.5 3.5e-07 29.7 2.4 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE31510.1 - 7.1e-07 28.8 3.1 7.1e-07 28.8 2.2 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPE31510.1 - 5e-06 26.2 10.8 8.6e-06 25.5 4.1 3.1 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EPE31510.1 - 9.9e-06 25.1 1.7 9.9e-06 25.1 1.2 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE31510.1 - 0.0015 18.5 1.1 0.0015 18.5 0.8 2.4 2 2 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPE31510.1 - 0.005 16.6 0.3 0.019 14.7 0.2 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.7 EPE31510.1 - 0.021 14.9 1.8 0.072 13.2 0.1 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 EPE31510.1 - 1.2 8.8 6.6 0.53 9.9 2.4 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF2616 PF11077.3 EPE31510.1 - 1.8 8.0 7.3 5 6.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) Prok-RING_4 PF14447.1 EPE31510.1 - 3 7.4 10.5 0.17 11.4 1.9 2.9 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 COesterase PF00135.23 EPE31511.1 - 1e-85 288.5 2.1 5.9e-76 256.2 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE31511.1 - 0.00046 19.8 0.0 0.0013 18.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DPPIV_N PF00930.16 EPE31514.1 - 8e-109 363.4 0.4 1.1e-108 362.9 0.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EPE31514.1 - 1.1e-55 188.2 2.5 2e-55 187.2 1.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE31514.1 - 3.4e-10 39.8 0.1 6.7e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EPE31514.1 - 5.8e-08 32.4 1.5 7.5e-07 28.8 0.4 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EPE31514.1 - 5.1e-07 29.7 0.1 1.2e-05 25.3 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 EPE31514.1 - 0.0016 17.7 0.1 0.0055 16.0 0.0 1.9 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region PAF-AH_p_II PF03403.8 EPE31514.1 - 0.0041 15.4 0.0 0.52 8.5 0.0 2.2 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II DLH PF01738.13 EPE31514.1 - 0.0087 15.3 0.1 0.048 12.9 0.1 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EPE31514.1 - 0.036 13.5 0.1 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EPE31514.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold WEMBL PF05701.6 EPE31515.1 - 0.0039 15.7 23.9 0.0051 15.3 16.6 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light ATG16 PF08614.6 EPE31515.1 - 8.8 6.0 18.4 4.7 6.9 3.2 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Carb_kinase PF01256.12 EPE31516.1 - 1.4e-55 188.2 0.0 1.9e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EPE31516.1 - 0.039 13.1 0.0 0.14 11.3 0.0 1.9 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase 7TM-7TMR_HD PF07698.6 EPE31518.1 - 0.063 12.7 1.5 0.14 11.5 0.1 1.9 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase DUF1201 PF06716.6 EPE31518.1 - 0.43 10.4 3.9 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) RHD3 PF05879.7 EPE31519.1 - 0 1035.4 0.0 0 1035.2 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EPE31519.1 - 2.4e-08 33.3 0.1 3.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EPE31519.1 - 1.8e-06 27.8 0.0 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EPE31519.1 - 0.00039 20.3 0.0 0.00099 19.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EPE31519.1 - 0.00085 19.3 0.1 0.0033 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EPE31519.1 - 0.016 15.7 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AA_permease_2 PF13520.1 EPE31520.1 - 1.2e-58 198.7 59.8 1.4e-58 198.4 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE31520.1 - 5.4e-33 114.0 55.4 7e-33 113.6 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease DPBB_1 PF03330.13 EPE31521.1 - 0.00035 20.4 0.3 0.00054 19.9 0.2 1.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Glyco_hydro_16 PF00722.16 EPE31522.1 - 1.7e-10 40.5 0.1 1.4e-09 37.5 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Toxin_13 PF07822.6 EPE31522.1 - 0.02 14.7 2.0 0.044 13.6 1.4 1.6 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein Glyco_transf_34 PF05637.7 EPE31523.1 - 8.9e-63 211.9 0.4 1.4e-62 211.3 0.3 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Spt5_N PF11942.3 EPE31524.1 - 0.43 11.2 4.1 0.31 11.6 0.4 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.1 EPE31524.1 - 5.1 7.4 11.9 23 5.4 0.6 3.4 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HET PF06985.6 EPE31525.1 - 3.6e-28 98.4 0.2 6.1e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BNR PF02012.15 EPE31526.1 - 2e-13 47.9 25.7 0.081 12.7 0.0 11.1 10 0 0 10 10 10 7 BNR/Asp-box repeat BNR_2 PF13088.1 EPE31526.1 - 1e-06 28.2 2.3 1.6 7.9 0.0 5.6 5 2 1 6 6 6 3 BNR repeat-like domain DUF3619 PF12279.3 EPE31528.1 - 0.037 14.0 0.0 0.084 12.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) Glyco_hydro_53 PF07745.8 EPE31529.1 - 5e-84 281.9 0.0 5.7e-84 281.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Myb_DNA-bind_3 PF12776.2 EPE31529.1 - 0.13 12.9 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Mpv17_PMP22 PF04117.7 EPE31530.1 - 1.5e-23 82.1 0.1 3.4e-23 81.0 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family PGK PF00162.14 EPE31531.1 - 1e-145 485.1 1.4 1.1e-145 484.9 1.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FIVAR PF07554.8 EPE31531.1 - 0.077 13.2 0.3 10 6.5 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised Sugar-binding Domain DSS1_SEM1 PF05160.8 EPE31532.1 - 5.5e-23 80.5 15.5 7.6e-23 80.0 10.7 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.4 EPE31533.1 - 5.2e-118 394.5 0.0 6.2e-118 394.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_8 PF13181.1 EPE31533.1 - 0.075 12.8 0.7 8.3 6.4 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EPE31534.1 - 1.7e-18 66.4 0.0 2.8e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE31534.1 - 8.5e-07 28.7 13.1 1.4e-06 28.1 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 EPE31534.1 - 0.94 8.8 10.9 1.9 7.8 7.5 1.4 1 0 0 1 1 1 0 Vta1 like Fungal_trans PF04082.13 EPE31535.1 - 2.3e-24 85.7 1.3 3.5e-24 85.0 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE31535.1 - 1.6e-07 31.1 9.7 3.2e-07 30.1 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gemini_mov PF01708.11 EPE31536.1 - 0.1 12.1 0.1 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 Geminivirus putative movement protein SNF5 PF04855.7 EPE31537.1 - 4.9e-82 275.0 0.0 7.6e-82 274.4 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EPE31537.1 - 0.0094 15.2 1.2 0.02 14.2 0.8 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF3060 PF11259.3 EPE31538.1 - 0.017 14.7 0.3 0.5 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) Glypican PF01153.14 EPE31538.1 - 0.26 9.8 1.6 0.31 9.5 1.1 1.1 1 0 0 1 1 1 0 Glypican Proteasom_Rpn13 PF04683.8 EPE31539.1 - 3e-28 97.7 0.0 4.6e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor MoaF PF10703.4 EPE31539.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F Ribosomal_L6e PF01159.14 EPE31540.1 - 4.1e-37 126.7 2.0 5.6e-37 126.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L6e Peptidase_M49 PF03571.10 EPE31541.1 - 1.3e-224 746.4 0.0 1.5e-224 746.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Ribosomal_L6 PF00347.18 EPE31542.1 - 4.7e-23 81.4 8.8 3e-12 46.8 0.3 3.1 3 0 0 3 3 3 3 Ribosomal protein L6 Acetyltransf_1 PF00583.19 EPE31543.1 - 3e-07 30.3 0.1 1.7e-06 27.9 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE31543.1 - 1.3e-06 28.4 0.0 1.2e-05 25.3 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE31543.1 - 1.9e-06 27.9 0.0 0.00026 21.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE31543.1 - 0.00023 20.8 0.0 0.00048 19.8 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EPE31543.1 - 0.00027 20.7 0.0 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE31543.1 - 0.00091 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 EPE31543.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Ammonium_transp PF00909.16 EPE31545.1 - 3.8e-116 387.8 31.4 4.3e-116 387.6 21.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DNA_pol_B_palm PF14792.1 EPE31546.1 - 2e-33 114.8 0.0 5.2e-33 113.4 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 EPE31546.1 - 5.8e-20 70.5 0.2 3.8e-19 67.9 0.0 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EPE31546.1 - 4.8e-19 67.8 0.0 1e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 EPE31546.1 - 7.9e-14 51.5 0.1 1.8e-12 47.2 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT PF00533.21 EPE31546.1 - 0.00016 21.7 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 EPE31546.1 - 0.015 15.5 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain PsbU PF06514.6 EPE31546.1 - 0.024 14.4 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) Ebola_NP PF05505.7 EPE31546.1 - 0.42 8.6 2.3 0.59 8.1 1.6 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Glutaredoxin PF00462.19 EPE31548.1 - 2e-14 53.2 0.0 1.7e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin MFS_1 PF07690.11 EPE31549.1 - 9.2e-39 133.1 37.0 9.2e-39 133.1 25.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 EPE31549.1 - 0.77 10.1 0.0 0.77 10.1 0.0 3.2 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PP2C PF00481.16 EPE31550.1 - 1.1e-29 103.6 0.0 1.6e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EPE31550.1 - 0.0039 16.6 0.0 0.01 15.2 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EPE31550.1 - 0.012 15.3 0.0 5.2 6.7 0.0 2.8 2 1 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) CBFD_NFYB_HMF PF00808.18 EPE31551.1 - 7.8e-10 38.6 0.0 1.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPE31551.1 - 0.0018 18.3 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PPP4R2 PF09184.6 EPE31551.1 - 9.4 5.6 18.5 14 5.0 12.8 1.4 1 0 0 1 1 1 0 PPP4R2 TMEM154 PF15102.1 EPE31552.1 - 0.097 12.3 4.3 0.41 10.3 3.0 2.0 1 1 0 1 1 1 0 TMEM154 protein family HRXXH PF13933.1 EPE31553.1 - 5e-06 26.1 1.8 2.2e-05 24.0 1.3 1.8 1 1 0 1 1 1 1 Putative peptidase family Pkinase PF00069.20 EPE31554.1 - 1.2e-66 224.5 0.0 2.1e-66 223.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE31554.1 - 2.2e-36 125.2 0.0 4.1e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE31554.1 - 1.3e-08 34.1 0.0 2.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPE31554.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family SLD3 PF08639.5 EPE31555.1 - 2.1e-125 419.2 3.1 2.1e-125 419.2 2.1 1.6 2 0 0 2 2 2 1 DNA replication regulator SLD3 APH PF01636.18 EPE31555.1 - 1.1e-13 51.5 0.0 2.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Apq12 PF12716.2 EPE31556.1 - 3.5e-08 33.0 8.8 3.5e-08 33.0 6.1 1.7 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis vMSA PF00695.14 EPE31556.1 - 0.0039 16.4 0.6 0.0051 16.0 0.4 1.1 1 0 0 1 1 1 1 Major surface antigen from hepadnavirus ATP_bind_1 PF03029.12 EPE31557.1 - 1.7e-72 243.8 0.0 2e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EPE31557.1 - 2.1e-06 28.5 0.0 6.4e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPE31557.1 - 0.00051 19.9 0.0 0.00087 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EPE31557.1 - 0.00057 19.3 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 EPE31557.1 - 0.00078 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EPE31557.1 - 0.0017 18.5 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPE31557.1 - 0.0023 17.9 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EPE31557.1 - 0.0072 16.4 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.18 EPE31557.1 - 0.01 15.8 0.0 0.033 14.1 0.0 2.0 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 EPE31557.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EPE31557.1 - 0.013 14.2 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_31 PF13614.1 EPE31557.1 - 0.019 14.8 0.0 0.055 13.4 0.0 1.9 2 1 0 2 2 1 0 AAA domain T2SE PF00437.15 EPE31557.1 - 0.023 13.6 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EPE31557.1 - 0.026 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EPE31557.1 - 0.028 14.7 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.12 EPE31557.1 - 0.029 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EPE31557.1 - 0.031 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EPE31557.1 - 0.043 14.1 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain GTP_EFTU PF00009.22 EPE31557.1 - 0.045 13.1 0.0 4.1 6.7 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.1 EPE31557.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EPE31557.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain KaiC PF06745.8 EPE31557.1 - 0.082 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC cobW PF02492.14 EPE31557.1 - 0.082 12.3 0.0 2.9 7.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EPE31557.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPE31557.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 EPE31557.1 - 0.093 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 EPE31557.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EPE31557.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain PPV_E1_C PF00519.12 EPE31557.1 - 0.15 10.6 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase NTPase_1 PF03266.10 EPE31557.1 - 0.17 11.5 0.0 0.94 9.1 0.0 1.9 2 0 0 2 2 2 0 NTPase S-AdoMet_synt_C PF02773.11 EPE31558.1 - 5.3e-76 252.9 0.1 1.1e-75 251.9 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EPE31558.1 - 2.8e-48 162.7 0.0 5e-48 161.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EPE31558.1 - 1.4e-42 143.9 0.5 3.7e-42 142.6 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain RIC1 PF07064.8 EPE31560.1 - 1.4e-92 309.8 0.1 1.9e-92 309.3 0.0 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 EPE31560.1 - 0.00012 21.7 4.1 0.65 9.9 0.2 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40 PF00400.27 EPE31561.1 - 5.2e-30 102.2 11.3 1.1e-07 31.3 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EPE31561.1 - 0.00033 19.0 0.0 0.021 13.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 EPE31561.1 - 0.00034 18.8 0.2 0.026 12.6 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EPE31561.1 - 0.0006 19.5 0.1 0.14 11.8 0.0 3.7 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EPE31561.1 - 0.012 14.3 1.1 2 7.0 0.1 2.8 1 1 1 2 2 2 0 Nup133 N terminal like DUF1513 PF07433.6 EPE31561.1 - 0.021 13.7 0.0 1.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Fungal_trans PF04082.13 EPE31562.1 - 2.5e-15 56.0 0.5 1.2e-14 53.8 0.1 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE31562.1 - 1.5e-09 37.5 9.7 3.1e-09 36.5 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4490 PF14892.1 EPE31562.1 - 0.38 10.4 3.2 0.26 10.9 0.3 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4490) Ribosomal_L2_C PF03947.13 EPE31563.1 - 8.6e-46 154.9 0.6 1.7e-45 153.9 0.4 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPE31563.1 - 3.2e-27 94.2 0.5 7.3e-27 93.1 0.3 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 EPE31564.1 - 3.9e-45 152.5 0.2 5e-44 148.9 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPE31564.1 - 9e-36 122.3 0.1 1.6e-35 121.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain MFS_1 PF07690.11 EPE31565.1 - 1.1e-29 103.2 42.5 9.5e-20 70.5 15.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE31565.1 - 7e-19 67.7 24.3 4.2e-17 61.8 16.8 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter Ank PF00023.25 EPE31566.1 - 2.7e-21 74.2 0.1 7.9e-07 28.5 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EPE31566.1 - 2.4e-20 72.6 0.0 3.7e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE31566.1 - 5.2e-16 58.6 0.0 3.5e-09 36.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE31566.1 - 1.5e-15 56.8 0.0 1.5e-10 40.9 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE31566.1 - 3e-13 48.5 0.0 0.00054 19.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.16 EPE31566.1 - 0.024 14.5 5.0 0.04 13.8 3.4 1.3 1 0 0 1 1 1 0 bZIP transcription factor Tannase PF07519.6 EPE31567.1 - 2.7e-77 260.5 0.8 1.7e-44 152.3 0.0 2.1 1 1 1 2 2 2 2 Tannase and feruloyl esterase FA_hydroxylase PF04116.8 EPE31567.1 - 1.9e-11 44.3 6.9 1.9e-11 44.3 4.8 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4190 PF13828.1 EPE31567.1 - 0.066 12.7 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Abhydrolase_6 PF12697.2 EPE31568.1 - 7.8e-20 71.7 0.2 2.4e-19 70.1 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE31568.1 - 3.1e-08 33.4 0.1 0.0081 15.9 0.0 2.6 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE31568.1 - 1.2e-07 31.5 0.0 7.8e-07 28.8 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE31568.1 - 0.1 11.7 0.0 0.48 9.6 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family PAP2 PF01569.16 EPE31569.1 - 4.4e-23 81.3 2.1 3e-22 78.6 0.2 2.3 2 0 0 2 2 2 1 PAP2 superfamily Aldo_ket_red PF00248.16 EPE31570.1 - 2e-56 190.9 0.0 2.5e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Inhibitor_I34 PF10466.4 EPE31570.1 - 0.39 10.8 5.1 1.2 9.2 0.2 3.3 3 0 0 3 3 3 0 Saccharopepsin inhibitor I34 Polysacc_deac_1 PF01522.16 EPE31571.1 - 4.8e-26 90.8 0.0 8.2e-26 90.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EPE31571.1 - 8.4e-10 38.4 38.7 5.8e-05 22.9 11.5 3.0 2 1 0 2 2 2 2 Chitin recognition protein CK_II_beta PF01214.13 EPE31572.1 - 3.1e-70 235.4 0.7 4.7e-70 234.8 0.5 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Nucleoplasmin PF03066.10 EPE31572.1 - 0.64 9.5 6.3 1.1 8.7 4.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin HMG_box_2 PF09011.5 EPE31573.1 - 3.1e-07 30.6 1.3 6.8e-06 26.3 0.1 3.0 3 0 0 3 3 3 2 HMG-box domain HMG_box PF00505.14 EPE31573.1 - 6.2e-07 29.5 5.2 0.00022 21.4 0.5 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box Phytochelatin PF05023.9 EPE31573.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Phytochelatin synthase DEAD PF00270.24 EPE31574.1 - 2.6e-45 153.9 0.0 4.4e-44 149.9 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE31574.1 - 8.6e-24 83.2 0.0 3e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPE31574.1 - 0.0039 16.0 0.0 0.0075 15.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EPE31574.1 - 0.053 13.3 0.0 0.17 11.6 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit WLM PF08325.5 EPE31575.1 - 0.068 13.0 0.5 0.068 13.0 0.3 1.8 2 0 0 2 2 2 0 WLM domain zf-C2H2 PF00096.21 EPE31576.1 - 9.9e-13 47.6 74.8 4e-05 23.7 1.7 10.5 10 1 0 10 10 10 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPE31576.1 - 5.1e-08 32.8 8.9 1e-05 25.5 0.2 7.6 8 1 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPE31576.1 - 1.7e-06 27.9 80.1 0.0076 16.5 0.5 10.3 11 0 0 11 11 11 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPE31576.1 - 0.0001 22.0 24.9 0.0066 16.3 0.4 5.9 5 0 0 5 5 5 3 C2H2-type zinc finger Ribosomal_L29 PF00831.18 EPE31577.1 - 6e-17 61.0 0.4 6e-17 61.0 0.2 1.9 2 1 1 3 3 3 1 Ribosomal L29 protein V-SNARE_C PF12352.3 EPE31578.1 - 1.1e-13 50.9 0.2 1.1e-13 50.9 0.1 3.4 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus IncA PF04156.9 EPE31578.1 - 0.028 14.0 10.2 0.053 13.1 7.1 1.4 1 0 0 1 1 1 0 IncA protein Rab3-GTPase_cat PF13890.1 EPE31578.1 - 0.059 12.7 0.9 0.085 12.2 0.2 1.6 2 0 0 2 2 2 0 Rab3 GTPase-activating protein catalytic subunit PA28_beta PF02252.13 EPE31578.1 - 0.09 12.2 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit MbeD_MobD PF04899.7 EPE31578.1 - 0.13 12.2 2.7 1.3 8.9 0.0 3.1 3 0 0 3 3 3 0 MbeD/MobD like Peptidase_S46 PF10459.4 EPE31578.1 - 0.17 10.2 2.2 0.2 10.0 1.5 1.1 1 0 0 1 1 1 0 Peptidase S46 Cep57_MT_bd PF06657.8 EPE31578.1 - 0.35 10.8 6.2 0.2 11.6 1.5 2.2 1 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APG6 PF04111.7 EPE31578.1 - 0.37 9.7 9.8 0.32 9.9 5.9 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 EPE31578.1 - 0.42 11.0 7.5 0.45 10.9 2.0 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CENP-H PF05837.7 EPE31578.1 - 0.47 10.6 6.6 1.2 9.3 4.6 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FliT PF05400.8 EPE31578.1 - 0.61 10.5 14.5 0.36 11.2 8.2 1.9 1 1 1 2 2 2 0 Flagellar protein FliT DEDD_Tnp_IS110 PF01548.12 EPE31578.1 - 1.1 8.9 5.9 3.1 7.4 1.2 2.3 1 1 1 2 2 2 0 Transposase Exonuc_VII_L PF02601.10 EPE31578.1 - 2 7.5 7.7 2.5 7.2 5.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Flagellin_N PF00669.15 EPE31578.1 - 2.3 8.0 7.8 0.27 11.0 1.2 2.4 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region DUF342 PF03961.8 EPE31578.1 - 6.3 5.0 6.2 11 4.2 3.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) MerR-DNA-bind PF09278.6 EPE31578.1 - 7.2 7.0 12.8 2 8.8 2.3 3.2 1 1 2 3 3 3 0 MerR, DNA binding ATP-synt_10 PF05176.9 EPE31579.1 - 2.8e-86 288.8 0.0 3.7e-86 288.5 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein 2-oxoacid_dh PF00198.18 EPE31580.1 - 6.3e-72 241.5 0.1 1.1e-71 240.7 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EPE31580.1 - 1.8e-17 62.7 0.0 3.4e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EPE31580.1 - 5.3e-12 45.1 1.4 9.2e-12 44.4 0.0 2.2 3 0 0 3 3 3 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EPE31580.1 - 0.014 15.0 0.1 0.036 13.7 0.1 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like SKI PF01202.17 EPE31581.1 - 7.5e-12 45.3 0.0 8.8e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EPE31581.1 - 2.1e-10 41.4 0.0 3.6e-10 40.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPE31581.1 - 8.7e-10 38.6 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPE31581.1 - 2.4e-08 34.3 0.0 4.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EPE31581.1 - 4.5e-05 22.3 0.0 6.5e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 EPE31581.1 - 0.00029 20.0 0.0 0.00039 19.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EPE31581.1 - 0.0011 18.6 0.1 0.0045 16.7 0.0 2.1 3 0 0 3 3 1 1 Part of AAA domain AAA PF00004.24 EPE31581.1 - 0.0011 19.1 0.1 0.0026 17.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EPE31581.1 - 0.0012 18.5 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase ABC_tran PF00005.22 EPE31581.1 - 0.0018 18.5 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EPE31581.1 - 0.0023 18.0 0.0 0.0048 17.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPE31581.1 - 0.0026 17.1 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPE31581.1 - 0.0031 17.6 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 EPE31581.1 - 0.0083 16.0 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EPE31581.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EPE31581.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPE31581.1 - 0.014 15.3 0.1 0.031 14.2 0.0 1.7 2 1 0 2 2 1 0 AAA ATPase domain CoaE PF01121.15 EPE31581.1 - 0.016 14.5 0.0 0.037 13.4 0.0 1.7 1 0 0 1 1 1 0 Dephospho-CoA kinase NTPase_1 PF03266.10 EPE31581.1 - 0.017 14.8 0.5 0.57 9.8 0.0 2.3 2 1 0 2 2 2 0 NTPase AAA_29 PF13555.1 EPE31581.1 - 0.017 14.6 0.1 0.032 13.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.1 EPE31581.1 - 0.024 14.2 0.1 0.12 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPE31581.1 - 0.024 14.6 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EPE31581.1 - 0.028 13.4 0.1 0.23 10.4 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 EPE31581.1 - 0.035 13.6 0.3 0.09 12.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 EPE31581.1 - 0.043 13.7 0.1 0.21 11.4 0.1 2.1 1 1 0 1 1 1 0 Cytidylate kinase-like family IPT PF01745.11 EPE31581.1 - 0.05 12.7 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Mg_chelatase PF01078.16 EPE31581.1 - 0.066 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PRK PF00485.13 EPE31581.1 - 0.08 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 EPE31581.1 - 0.082 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DNA_pol3_delta2 PF13177.1 EPE31581.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit SRP54 PF00448.17 EPE31581.1 - 0.12 11.7 0.1 3.3 7.1 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 EPE31581.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase MutS_V PF00488.16 EPE31581.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 MutS domain V PhoH PF02562.11 EPE31581.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 EPE31581.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain HpcH_HpaI PF03328.9 EPE31582.1 - 2.9e-36 124.4 0.0 3.7e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Coiled-coil_56 PF09813.4 EPE31585.1 - 5.5e-05 23.0 0.0 6.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 EPE31586.1 - 9e-61 205.3 2.3 4.2e-58 196.5 1.6 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3453) Pectate_lyase_3 PF12708.2 EPE31590.1 - 2.1e-82 276.5 26.5 1.1e-66 225.2 5.0 3.6 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EPE31590.1 - 1.1e-05 24.7 2.5 0.059 12.8 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PNGaseA PF12222.3 EPE31591.1 - 2.1e-114 382.7 8.6 2.8e-114 382.3 5.9 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1283 PF06932.6 EPE31592.1 - 0.07 13.1 0.3 0.091 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) THF_DHG_CYH PF00763.18 EPE31593.1 - 1.9e-19 69.8 0.0 3.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EPE31593.1 - 1.9e-14 53.0 0.0 1.5e-12 46.8 0.0 2.5 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MMS19_N PF14500.1 EPE31594.1 - 1e-36 126.5 0.1 2.1e-34 118.9 0.0 3.5 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EPE31594.1 - 1.5e-22 79.9 0.2 3.5e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT PF02985.17 EPE31594.1 - 0.014 15.4 4.1 7.1 7.0 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat DUF106 PF01956.11 EPE31595.1 - 3.3e-55 186.1 2.6 4.7e-55 185.6 1.8 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 EPE31596.1 - 2.2e-49 167.1 3.1 2.9e-49 166.7 2.1 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Brix PF04427.13 EPE31597.1 - 1.5e-34 119.3 0.1 2e-34 118.9 0.1 1.2 1 0 0 1 1 1 1 Brix domain Hex_IIIa PF02455.11 EPE31597.1 - 0.0069 15.1 0.0 0.0098 14.6 0.0 1.2 1 0 0 1 1 1 1 Hexon-associated protein (IIIa) Tim17 PF02466.14 EPE31598.1 - 2.3e-26 92.3 0.7 3.6e-26 91.7 0.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Prenylcys_lyase PF07156.9 EPE31600.1 - 2.4e-09 36.5 0.0 4e-08 32.5 0.0 2.6 2 1 0 2 2 2 1 Prenylcysteine lyase NAD_binding_9 PF13454.1 EPE31600.1 - 2.8e-07 30.4 0.2 7.1e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EPE31600.1 - 3.6e-06 26.9 0.0 1.4e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPE31600.1 - 4.8e-06 26.7 0.0 0.019 15.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE31600.1 - 0.00084 18.3 0.1 0.01 14.7 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase eIF-3_zeta PF05091.7 EPE31601.1 - 1.4e-206 687.0 0.0 1.8e-206 686.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 EPE31601.1 - 0.0045 16.4 0.1 0.011 15.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF569) bZIP_1 PF00170.16 EPE31602.1 - 6.6e-05 22.7 9.3 0.00014 21.7 6.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 EPE31602.1 - 0.0069 16.1 5.0 0.17 11.4 0.0 2.4 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_2 PF07716.10 EPE31602.1 - 0.012 15.4 3.4 0.012 15.4 2.3 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF904 PF06005.7 EPE31602.1 - 0.038 14.2 1.8 0.038 14.2 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_Maf PF03131.12 EPE31602.1 - 1.1 9.5 8.0 2.5 8.4 5.5 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor DFF-C PF09033.5 EPE31602.1 - 3.2 7.5 6.0 17 5.2 2.3 2.7 2 1 1 3 3 3 0 DNA Fragmentation factor 45kDa, C terminal domain Acyltransferase PF01553.16 EPE31603.1 - 3.2e-14 52.4 0.0 4.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Asn_synthase PF00733.16 EPE31605.1 - 8e-53 179.5 0.0 1.2e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EPE31605.1 - 0.00012 21.8 0.0 0.00058 19.5 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain VPS9 PF02204.13 EPE31606.1 - 3e-29 101.0 0.0 5.4e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EPE31606.1 - 4.4e-10 38.8 0.1 9e-09 34.6 0.0 2.3 2 0 0 2 2 2 1 CUE domain DUF3824 PF12868.2 EPE31607.1 - 1 10.3 10.6 0.79 10.6 4.4 2.8 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) CRC_subunit PF08624.5 EPE31609.1 - 8.5e-56 187.7 0.1 1.2e-55 187.2 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit LRR_4 PF12799.2 EPE31610.1 - 0.14 11.7 7.9 3 7.5 0.6 4.6 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE31610.1 - 4.2 7.2 6.6 5.3 6.8 0.5 3.1 3 0 0 3 3 3 0 Leucine rich repeat Amidoligase_2 PF12224.3 EPE31611.1 - 2.1e-30 106.1 0.0 4.1e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Putative amidoligase enzyme Lipase_GDSL PF00657.17 EPE31613.1 - 1.4e-16 61.1 0.2 2.2e-16 60.4 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EPE31613.1 - 0.00011 22.3 3.7 0.00018 21.7 2.6 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family VIT1 PF01988.14 EPE31614.1 - 6.4e-54 182.6 5.6 7.4e-54 182.4 3.9 1.0 1 0 0 1 1 1 1 VIT family Glyco_hydro_88 PF07470.8 EPE31615.1 - 1.8e-17 63.3 0.2 2.5e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_114 PF03537.8 EPE31616.1 - 9.9e-26 89.3 0.1 2.9e-25 87.8 0.1 1.8 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 DUF605 PF04652.11 EPE31616.1 - 0.025 14.0 7.7 0.039 13.3 5.4 1.2 1 0 0 1 1 1 0 Vta1 like DUF4592 PF15262.1 EPE31616.1 - 8.3 6.9 10.9 12 6.4 6.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4592) APH PF01636.18 EPE31617.1 - 3.9e-08 33.3 0.0 5.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE31617.1 - 0.00039 20.0 0.0 0.00068 19.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase MFS_1 PF07690.11 EPE31618.1 - 2e-31 108.9 78.5 5.9e-27 94.3 31.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE31618.1 - 3.3e-07 29.2 7.0 3.3e-07 29.2 4.9 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EPE31618.1 - 0.00016 20.0 6.4 0.00024 19.4 4.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cu_amine_oxid PF01179.15 EPE31619.1 - 5.8e-173 575.3 0.1 6.9e-173 575.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EPE31619.1 - 1.3e-21 76.5 0.1 3.8e-21 75.0 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EPE31619.1 - 1.6e-12 47.3 0.0 2.8e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RdgC PF04381.7 EPE31619.1 - 0.063 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative exonuclease, RdgC Tfb2 PF03849.9 EPE31622.1 - 4.4e-137 456.6 0.1 8.2e-137 455.7 0.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EPE31622.1 - 1.1e-05 25.2 0.0 3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.17 EPE31623.1 - 1.1e-11 44.6 0.1 1.7e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EPE31623.1 - 0.018 14.9 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Sugar_tr PF00083.19 EPE31624.1 - 1.1e-109 366.9 20.8 1.4e-109 366.7 14.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE31624.1 - 8e-23 80.7 42.0 5.7e-22 77.9 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SPW PF03779.9 EPE31626.1 - 0.44 9.9 7.3 0.77 9.1 5.1 1.3 1 0 0 1 1 1 0 SPW repeat Arm PF00514.18 EPE31627.1 - 9.6e-05 22.0 5.9 2.2 8.2 0.0 5.8 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat KAP PF05804.7 EPE31627.1 - 0.00012 20.2 0.1 0.011 13.6 0.0 2.2 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) Merozoite_SPAM PF07133.6 EPE31627.1 - 0.013 15.4 0.7 0.06 13.2 0.9 1.7 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) NA37 PF04245.8 EPE31628.1 - 0.003 16.9 1.2 0.003 16.9 0.9 1.5 2 0 0 2 2 2 1 37-kD nucleoid-associated bacterial protein DUF4201 PF13870.1 EPE31628.1 - 0.004 16.6 3.2 0.004 16.6 2.2 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Flavin_Reduct PF01613.13 EPE31628.1 - 0.017 14.9 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 Flavin reductase like domain LRR_4 PF12799.2 EPE31629.1 - 2.6e-36 122.6 48.3 6.4e-07 28.8 2.3 10.6 6 3 5 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE31629.1 - 1.2e-34 117.8 44.7 5.2e-08 32.5 3.4 8.6 5 2 3 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 EPE31629.1 - 3.9e-18 62.7 50.2 0.11 12.6 0.1 16.6 18 1 0 18 18 18 7 Leucine Rich Repeat LRR_7 PF13504.1 EPE31629.1 - 1.5e-12 45.5 44.9 0.82 10.1 0.0 14.5 15 0 0 15 15 15 8 Leucine rich repeat LRR_6 PF13516.1 EPE31629.1 - 0.017 15.1 48.2 4.5 7.6 0.4 13.2 13 1 1 14 14 14 0 Leucine Rich repeat Lactamase_B PF00753.22 EPE31631.1 - 1.8e-06 27.7 0.1 9.8e-06 25.3 0.0 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPE31631.1 - 2.9e-05 23.6 0.0 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pribosyltran PF00156.22 EPE31632.1 - 1.2e-08 34.6 0.2 9.9e-08 31.7 0.1 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain 2-Hacid_dh_C PF02826.14 EPE31633.1 - 7.7e-45 152.2 0.1 1.7e-30 105.4 0.0 2.8 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EPE31633.1 - 0.011 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EPE31633.1 - 0.021 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.25 EPE31633.1 - 0.046 13.1 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_10 PF13460.1 EPE31633.1 - 0.068 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 EPE31633.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_16 PF10294.4 EPE31635.1 - 1.1e-44 151.9 0.0 1.5e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EPE31635.1 - 0.0098 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EPE31635.1 - 0.028 14.0 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EPE31635.1 - 0.061 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain WW PF00397.21 EPE31636.1 - 0.00056 19.7 3.0 0.018 14.9 0.0 3.2 3 0 0 3 3 3 2 WW domain EF-hand_4 PF12763.2 EPE31636.1 - 0.0047 16.6 0.2 0.61 9.8 0.0 2.9 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand UvdE PF03851.9 EPE31637.1 - 1.7e-110 368.4 0.0 2.2e-110 368.0 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE KRAB PF01352.22 EPE31638.1 - 0.18 11.3 3.8 0.43 10.0 2.4 1.8 2 0 0 2 2 2 0 KRAB box CC PF04942.9 EPE31642.1 - 0.055 13.3 0.2 0.099 12.5 0.2 1.4 1 0 0 1 1 1 0 CC domain CMD PF02627.15 EPE31644.1 - 0.00014 21.6 0.5 0.00026 20.7 0.0 1.7 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family PAP_assoc PF03828.14 EPE31645.1 - 2.3e-11 43.4 0.1 4.9e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPE31645.1 - 4.4e-09 36.5 0.0 1.1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.1 EPE31645.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) EF1G PF00647.14 EPE31646.1 - 3.5e-43 145.6 0.1 6e-43 144.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EPE31646.1 - 2.3e-13 49.9 0.0 9e-13 48.0 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPE31646.1 - 6.7e-10 39.0 0.1 5e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE31646.1 - 3.5e-09 36.4 0.0 7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPE31646.1 - 4.5e-09 36.4 0.1 1.2e-08 35.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EPE31646.1 - 1.1e-05 25.7 0.0 2.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPE31646.1 - 0.023 14.6 0.0 0.083 12.9 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain NIF PF03031.13 EPE31647.1 - 1.6e-17 63.6 0.0 2.4e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PAP1 PF08601.5 EPE31647.1 - 0.17 11.5 11.4 0.27 10.9 7.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Rrn6 PF10214.4 EPE31647.1 - 6.6 4.6 10.5 9.5 4.1 7.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF605 PF04652.11 EPE31647.1 - 8.8 5.6 18.6 15 4.8 12.9 1.3 1 0 0 1 1 1 0 Vta1 like DUF947 PF06102.7 EPE31648.1 - 2.2e-54 183.7 27.1 2.2e-54 183.7 18.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF947) ABC1 PF03109.11 EPE31649.1 - 1.9e-34 118.1 0.0 8.4e-34 116.0 0.0 2.2 2 0 0 2 2 2 1 ABC1 family Es2 PF09751.4 EPE31650.1 - 8.6e-101 338.3 5.7 1.8e-100 337.3 3.9 1.5 1 1 0 1 1 1 1 Nuclear protein Es2 DUF572 PF04502.8 EPE31650.1 - 0.033 13.4 1.0 0.051 12.7 0.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3595 PF12166.3 EPE31650.1 - 0.1 11.3 0.2 0.18 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF1918 PF08940.6 EPE31651.1 - 0.00067 18.9 1.5 4.1 6.8 0.0 4.3 4 0 0 4 4 4 2 Domain of unknown function (DUF1918) Whi5 PF08528.6 EPE31652.1 - 3.6e-09 35.9 0.2 6.6e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 Whi5 like CytochromB561_N PF09786.4 EPE31652.1 - 0.056 11.9 9.7 0.03 12.7 5.4 1.3 1 1 0 1 1 1 0 Cytochrome B561, N terminal Metallopep PF12044.3 EPE31653.1 - 1.1e-172 574.3 0.0 1.4e-172 573.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.1 EPE31653.1 - 0.00019 21.4 0.2 0.00019 21.4 0.2 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EPE31653.1 - 0.0033 17.5 0.1 0.0099 15.9 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EPE31653.1 - 0.071 13.6 0.2 0.23 11.9 0.1 1.9 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Jacalin PF01419.12 EPE31653.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Jacalin-like lectin domain CDP-OH_P_transf PF01066.16 EPE31654.1 - 8.2e-14 51.7 2.2 1.4e-13 50.9 1.5 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PqiA PF04403.8 EPE31654.1 - 0.016 14.7 0.2 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 Paraquat-inducible protein A DUF4345 PF14248.1 EPE31654.1 - 0.13 11.6 4.3 0.33 10.4 1.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4345) Gar1 PF04410.9 EPE31655.1 - 1.5e-43 147.9 0.1 3.3e-43 146.8 0.0 1.5 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 EPE31656.1 - 7.7e-45 152.5 0.3 1.5e-44 151.6 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPE31656.1 - 9.3e-17 60.7 0.2 1.8e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EPE31656.1 - 3.5e-13 49.1 0.0 7.3e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EPE31656.1 - 5.5e-11 42.1 0.0 1.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain ARL2_Bind_BART PF11527.3 EPE31656.1 - 0.034 13.9 0.5 2 8.2 0.0 3.4 3 0 0 3 3 3 0 The ARF-like 2 binding protein BART PH PF00169.24 EPE31657.1 - 2.7e-12 46.8 0.1 5.2e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 EPE31657.1 - 0.038 11.5 0.2 0.072 10.6 0.1 1.4 2 0 0 2 2 2 0 Prominin DUF2013 PF09431.5 EPE31658.1 - 1.3e-51 174.0 3.5 2.7e-51 173.0 2.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) DnaJ PF00226.26 EPE31659.1 - 2.7e-21 75.0 0.9 2.7e-21 75.0 0.6 3.1 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 EPE31659.1 - 1.9e-17 62.6 11.0 4.7e-10 38.9 0.0 5.5 4 1 2 6 6 6 4 TPR repeat TPR_2 PF07719.12 EPE31659.1 - 2.6e-13 48.7 13.2 0.0017 18.1 0.0 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPE31659.1 - 1.6e-12 46.4 12.5 5.3e-05 22.6 0.0 7.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPE31659.1 - 1.8e-12 46.9 1.2 0.01 15.6 0.0 4.9 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPE31659.1 - 1.7e-11 44.4 8.9 0.00014 22.3 1.8 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPE31659.1 - 4.8e-10 39.1 7.9 0.21 12.3 0.0 6.5 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPE31659.1 - 8.8e-07 29.1 12.6 0.063 13.6 1.0 4.7 5 1 0 5 5 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPE31659.1 - 2.5e-06 26.8 6.6 0.0037 16.9 0.0 6.4 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPE31659.1 - 3.6e-06 27.0 11.4 4.7 7.8 0.0 7.6 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPE31659.1 - 1.6e-05 24.7 2.3 0.0096 16.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPE31659.1 - 1.8e-05 24.5 14.4 0.34 10.8 0.2 6.7 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPE31659.1 - 2.1e-05 23.9 7.0 0.35 10.7 0.0 5.7 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPE31659.1 - 0.022 13.8 6.4 3 6.8 0.0 4.8 2 2 2 5 5 5 0 Tetratricopeptide repeat YfiO PF13525.1 EPE31659.1 - 0.033 13.6 3.2 0.1 12.0 0.1 3.0 3 1 1 4 4 4 0 Outer membrane lipoprotein TPR_18 PF13512.1 EPE31659.1 - 0.044 13.8 0.5 0.69 9.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ClpS PF02617.12 EPE31659.1 - 0.075 12.7 0.2 0.51 10.1 0.0 2.4 3 0 0 3 3 3 0 ATP-dependent Clp protease adaptor protein ClpS SAE2 PF08573.5 EPE31659.1 - 6.6 7.5 6.8 0.72 10.5 0.1 2.8 3 1 0 3 3 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Syntaxin PF00804.20 EPE31660.1 - 0.04 14.0 1.2 0.24 11.6 0.8 2.3 1 1 0 1 1 1 0 Syntaxin Hox9_act PF04617.8 EPE31660.1 - 0.063 13.4 0.1 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 Hox9 activation region IncA PF04156.9 EPE31660.1 - 0.58 9.7 10.5 0.032 13.8 1.8 2.2 1 1 0 2 2 2 0 IncA protein Syntaxin-6_N PF09177.6 EPE31660.1 - 0.78 10.1 4.5 0.99 9.8 0.3 2.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Vac14_Fig4_bd PF11916.3 EPE31661.1 - 1.8e-82 274.8 7.3 1.8e-82 274.8 5.0 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EPE31661.1 - 6.3e-47 157.9 0.0 8.3e-44 147.9 0.0 3.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EPE31661.1 - 8.9e-09 34.7 1.9 0.0004 20.2 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EPE31661.1 - 8.9e-07 29.2 7.8 0.0014 19.0 0.1 6.3 5 2 2 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.1 EPE31661.1 - 4.7e-06 26.8 6.1 0.0031 17.7 0.0 5.1 6 0 0 6 6 6 1 HEAT repeats Arm PF00514.18 EPE31661.1 - 0.01 15.6 0.0 13 5.8 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EPE31661.1 - 0.046 13.0 0.0 2.2 7.5 0.0 3.5 4 1 1 5 5 5 0 CLASP N terminal Pet191_N PF10203.4 EPE31664.1 - 0.052 13.6 1.9 0.35 10.9 1.5 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 EPE31664.1 - 0.066 13.1 0.1 0.15 11.9 0.1 1.6 1 1 0 1 1 1 0 CHCH domain UCR_hinge PF02320.11 EPE31664.1 - 0.07 13.0 0.5 0.1 12.5 0.3 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EPE31664.1 - 0.28 11.0 2.8 2.3 8.1 2.0 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) GFA PF04828.9 EPE31665.1 - 0.00027 20.8 0.1 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme FA_desaturase PF00487.19 EPE31667.1 - 8.2e-35 120.4 26.8 1.1e-34 120.0 18.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EPE31667.1 - 1.5e-13 50.3 0.0 3.1e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAM60A PF15396.1 EPE31667.1 - 0.041 13.6 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Pyr_redox_dim PF02852.17 EPE31669.1 - 3.7e-40 136.3 0.3 1.4e-39 134.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EPE31669.1 - 2.3e-37 128.8 16.2 7e-36 123.9 11.3 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE31669.1 - 5.6e-23 81.1 11.0 3.2e-19 69.0 0.8 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE31669.1 - 2.4e-10 40.2 4.0 2.4e-06 27.4 0.3 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EPE31669.1 - 6.6e-10 38.6 0.5 6.6e-10 38.6 0.4 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EPE31669.1 - 6.1e-09 35.2 14.3 7.9e-08 31.5 3.7 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EPE31669.1 - 1.3e-07 30.9 14.0 4.4e-05 22.5 0.2 3.9 4 0 0 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE31669.1 - 7e-07 28.4 2.8 7e-07 28.4 1.9 2.7 2 1 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EPE31669.1 - 1.9e-06 27.1 4.1 7.7e-05 21.8 0.1 2.4 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 EPE31669.1 - 2.7e-06 26.1 15.3 9e-05 21.1 1.2 4.1 4 0 0 4 4 4 2 HI0933-like protein Pyr_redox_3 PF13738.1 EPE31669.1 - 4.4e-06 26.8 6.3 0.024 14.6 2.8 3.2 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPE31669.1 - 0.0001 21.3 0.8 0.63 8.8 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EPE31669.1 - 0.00013 21.6 2.6 0.29 10.7 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EPE31669.1 - 0.0022 16.9 1.2 0.0098 14.8 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EPE31669.1 - 0.004 16.2 11.1 0.082 11.9 0.8 3.3 3 0 0 3 3 3 2 FAD binding domain XdhC_CoxI PF02625.11 EPE31669.1 - 0.042 13.4 0.6 0.68 9.6 0.0 2.5 2 0 0 2 2 2 0 XdhC and CoxI family Amino_oxidase PF01593.19 EPE31669.1 - 0.057 12.4 0.3 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 EPE31669.1 - 0.16 12.2 6.6 4.1 7.7 0.6 3.3 2 2 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EPE31669.1 - 0.49 10.0 8.1 0.28 10.8 0.7 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EPE31669.1 - 4.7 6.5 6.8 6.6 6.0 0.4 2.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HLH PF00010.21 EPE31670.1 - 1.3e-12 47.2 0.0 6.1e-12 45.0 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain NPR3 PF03666.8 EPE31671.1 - 3.1e-113 378.7 2.8 3.1e-113 378.7 1.9 2.4 2 1 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Dala_Dala_lig_N PF01820.16 EPE31671.1 - 0.0034 17.6 1.5 0.0049 17.1 0.1 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase N-terminus DEAD PF00270.24 EPE31673.1 - 9.8e-42 142.3 1.4 1.7e-41 141.5 1.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE31673.1 - 1.1e-21 76.4 0.0 8.3e-11 41.6 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EPE31673.1 - 9.6e-06 25.5 0.3 3.3e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EPE31673.1 - 1.2 8.9 5.5 15 5.4 3.8 2.5 1 1 0 1 1 1 0 Part of AAA domain Atrophin-1 PF03154.10 EPE31673.1 - 2.3 6.2 8.3 3.7 5.5 5.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF1682 PF07946.9 EPE31674.1 - 7.3e-110 366.7 0.0 8.3e-110 366.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF3635 PF12330.3 EPE31675.1 - 0.00011 22.2 0.5 0.016 15.2 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3635) Pkinase PF00069.20 EPE31675.1 - 0.02 14.0 0.0 0.044 12.9 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain Nucleoside_tran PF01733.13 EPE31676.1 - 3.9e-41 141.2 15.3 5.4e-39 134.1 10.6 2.6 1 1 0 1 1 1 1 Nucleoside transporter HMG_box PF00505.14 EPE31679.1 - 6.2e-17 61.6 0.9 1.6e-16 60.3 0.6 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPE31679.1 - 4.3e-14 52.6 0.6 1.1e-13 51.2 0.4 1.8 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 EPE31679.1 - 4.7e-09 36.2 0.0 8.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EPE31679.1 - 1.2e-06 28.2 0.0 2.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RIO1 PF01163.17 EPE31680.1 - 3.6e-70 235.1 1.1 4.7e-70 234.7 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EPE31680.1 - 6.8e-05 22.0 0.1 0.18 10.8 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE31680.1 - 0.011 15.5 0.2 0.93 9.1 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family IncA PF04156.9 EPE31684.1 - 0.027 14.0 15.7 0.19 11.2 2.2 2.4 2 0 0 2 2 2 0 IncA protein DUF1192 PF06698.6 EPE31684.1 - 0.044 13.5 5.1 0.37 10.6 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMF_DNA_bd PF12329.3 EPE31684.1 - 0.66 9.8 6.9 2.7 7.8 1.0 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 EPE31684.1 - 1 8.3 11.5 0.67 8.9 0.9 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF2353 PF09789.4 EPE31684.1 - 2.7 7.1 12.3 0.74 9.0 2.5 2.7 2 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Spc24 PF08286.6 EPE31684.1 - 3.3 7.4 11.5 3.6 7.3 0.3 3.1 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.4 EPE31684.1 - 3.8 7.3 14.5 6.6 6.5 4.5 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PspB PF06667.7 EPE31684.1 - 4.2 7.3 5.1 1.7 8.6 0.3 2.6 2 1 1 3 3 3 0 Phage shock protein B OmpH PF03938.9 EPE31684.1 - 7.8 6.4 8.2 3.9 7.4 1.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Rab5-bind PF09311.6 EPE31684.1 - 9.2 6.1 21.8 0.79 9.5 5.3 2.8 2 1 0 2 2 2 0 Rabaptin-like protein DUF904 PF06005.7 EPE31684.1 - 9.2 6.6 14.9 0.56 10.5 1.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF904) SYF2 PF08231.7 EPE31689.1 - 2.3e-53 180.4 12.2 2.3e-53 180.4 8.5 1.8 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.9 EPE31689.1 - 0.65 9.9 7.3 2.3 8.1 2.6 2.7 1 1 1 2 2 2 0 ARD/ARD' family NAD_binding_10 PF13460.1 EPE31690.1 - 6e-15 55.7 0.0 6.3e-14 52.3 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE31690.1 - 1e-07 31.6 0.0 2.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE31690.1 - 0.00016 20.4 0.0 0.00048 18.9 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPE31690.1 - 0.00064 18.7 0.0 0.026 13.4 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EPE31690.1 - 0.012 15.5 0.0 0.034 14.0 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EPE31690.1 - 0.031 13.1 0.0 0.15 10.9 0.0 2.1 2 1 1 3 3 3 0 RmlD substrate binding domain YEATS PF03366.11 EPE31691.1 - 1.3e-31 108.0 0.4 1.9e-31 107.6 0.3 1.2 1 0 0 1 1 1 1 YEATS family Ins_P5_2-kin PF06090.7 EPE31692.1 - 3.8e-48 164.1 0.0 9.5e-47 159.5 0.0 2.0 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF2404 PF10296.4 EPE31693.1 - 3.6e-05 23.8 0.0 0.00013 22.0 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Disintegrin PF00200.18 EPE31694.1 - 0.048 13.8 14.9 0.069 13.3 10.3 1.2 1 0 0 1 1 1 0 Disintegrin LtrA PF06772.6 EPE31695.1 - 2.7e-19 69.3 24.7 2.7e-19 69.3 17.1 2.1 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) F-box-like PF12937.2 EPE31696.1 - 0.00097 18.8 0.3 0.0024 17.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like ATP-synt_8 PF00895.15 EPE31697.1 - 2.7 8.2 8.2 1.5 9.0 0.0 3.5 3 0 0 3 3 3 0 ATP synthase protein 8 Hen1_L PF12623.2 EPE31698.1 - 0.025 13.3 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 SNARE PF05739.14 EPE31701.1 - 5.4e-19 67.6 2.6 1.5e-18 66.2 1.8 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EPE31701.1 - 5e-11 42.6 0.2 5e-11 42.6 0.1 2.3 2 1 0 2 2 2 1 Syntaxin Pox_Ag35 PF03286.9 EPE31701.1 - 0.29 10.6 2.8 0.27 10.7 0.1 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein MCPsignal PF00015.16 EPE31701.1 - 0.31 10.5 7.5 0.32 10.4 1.2 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DNA_repr_REX1B PF14966.1 EPE31701.1 - 0.86 10.0 5.3 2.7 8.4 0.1 3.0 3 1 0 3 3 3 0 DNA repair REX1-B IncA PF04156.9 EPE31701.1 - 2.8 7.4 8.4 16 5.0 0.3 3.2 3 0 0 3 3 3 0 IncA protein EF-hand_1 PF00036.27 EPE31702.1 - 1.8e-40 133.1 12.8 1.7e-09 36.2 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EPE31702.1 - 1.3e-35 121.2 7.2 1.2e-19 70.1 1.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EPE31702.1 - 3.3e-34 116.2 12.3 1.3e-15 56.6 0.5 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EPE31702.1 - 9.5e-30 99.7 8.4 2e-09 36.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EPE31702.1 - 2.9e-25 86.4 9.7 2.2e-06 26.7 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EPE31702.1 - 3.9e-15 55.5 0.3 4.2e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EPE31702.1 - 7.9e-09 35.1 1.8 0.0012 18.5 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EPE31702.1 - 2.9e-08 33.7 0.1 0.0076 16.2 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EPE31702.1 - 8.2e-08 31.7 0.1 0.036 13.6 0.0 3.5 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EPE31702.1 - 1.3e-06 28.2 2.1 9e-06 25.5 0.2 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EPE31702.1 - 0.00045 19.9 0.3 0.6 9.8 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EPE31702.1 - 0.00063 19.3 0.1 0.14 11.7 0.0 2.8 1 1 0 2 2 2 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 EPE31702.1 - 0.004 17.1 0.2 2.1 8.3 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb4 Tenui_NCP PF04876.7 EPE31702.1 - 0.0048 16.4 0.2 0.16 11.5 0.0 2.4 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 EPE31702.1 - 0.01 16.1 1.0 2.1 8.7 0.0 2.5 1 1 1 2 2 2 0 Toprim-like DUF2267 PF10025.4 EPE31702.1 - 0.013 15.5 0.0 0.12 12.4 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) DUF3349 PF11829.3 EPE31702.1 - 0.046 14.1 0.3 16 6.0 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) RloB PF13707.1 EPE31702.1 - 0.18 11.4 3.1 1.9 8.1 1.4 2.2 1 1 0 1 1 1 0 RloB-like protein MgtE_N PF03448.12 EPE31702.1 - 0.22 11.8 1.8 2.7 8.3 0.0 2.2 1 1 0 2 2 2 0 MgtE intracellular N domain EF-hand_10 PF14788.1 EPE31702.1 - 0.33 10.6 2.0 1.5 8.5 0.1 2.9 1 1 3 4 4 4 0 EF hand Glyco_hydro_47 PF01532.15 EPE31703.1 - 7.1e-168 558.9 0.0 8.3e-168 558.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EPE31703.1 - 0.061 11.5 0.0 6.9 4.8 0.0 2.1 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) F-box-like PF12937.2 EPE31705.1 - 6e-06 25.8 0.4 3.5e-05 23.4 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPE31705.1 - 2.8 7.7 8.1 13 5.5 0.3 3.4 3 1 0 3 3 3 0 F-box domain HAD_2 PF13419.1 EPE31706.1 - 4.4e-08 33.5 0.0 6.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPE31706.1 - 0.00062 20.2 0.0 0.00082 19.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE31706.1 - 0.00077 19.1 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like FAD_binding_1 PF00667.15 EPE31708.1 - 1.8e-43 148.5 0.0 2.8e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPE31708.1 - 8.5e-11 42.3 0.0 1.5e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Nitroreductase PF00881.19 EPE31709.1 - 2.7e-13 50.0 0.0 3.1e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family BTB PF00651.26 EPE31710.1 - 0.00057 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EPE31711.1 - 2.3e-07 30.7 0.0 4.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EPE31712.1 - 1.7e-16 60.1 0.0 4.6e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DUF3342 PF11822.3 EPE31712.1 - 0.012 14.7 0.3 2.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) DUF1882 PF08966.6 EPE31712.1 - 0.73 9.8 3.9 19 5.3 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) p450 PF00067.17 EPE31714.1 - 4.8e-44 150.6 0.0 4.3e-37 127.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Sec1 PF00995.18 EPE31714.1 - 0.15 10.6 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Sec1 family p450 PF00067.17 EPE31715.1 - 1e-39 136.3 0.0 1.1e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Prenyltrans_2 PF13249.1 EPE31716.1 - 2.2e-10 40.9 3.5 0.015 15.6 0.0 4.9 5 1 0 5 5 5 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPE31716.1 - 6.3e-06 26.1 0.2 0.059 13.3 0.0 3.0 2 0 0 2 2 2 2 Prenyltransferase-like Prenyltrans PF00432.16 EPE31716.1 - 0.0016 17.9 0.5 0.16 11.5 0.0 3.9 4 0 0 4 4 4 1 Prenyltransferase and squalene oxidase repeat BTB PF00651.26 EPE31717.1 - 9.2e-11 41.7 0.0 1.3e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.20 EPE31719.1 - 2.7e-42 144.7 0.0 3.4e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE31719.1 - 1.7e-25 89.5 0.0 2.4e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE31719.1 - 0.00049 19.1 0.0 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPE31719.1 - 0.0037 17.0 1.7 0.11 12.1 1.1 2.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family FHA PF00498.21 EPE31719.1 - 0.0037 17.3 0.2 0.018 15.1 0.0 2.2 3 0 0 3 3 3 1 FHA domain Kdo PF06293.9 EPE31719.1 - 0.0044 16.1 0.0 0.0084 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EPE31719.1 - 0.082 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Shisa PF13908.1 EPE31720.1 - 2.5e-08 34.3 0.7 3.1e-08 33.9 0.5 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator RCR PF12273.3 EPE31720.1 - 1.2e-06 29.0 7.1 1.9e-06 28.4 4.9 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1510 PF07423.6 EPE31720.1 - 4.5e-05 22.9 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF1183 PF06682.7 EPE31720.1 - 7.1e-05 22.5 0.6 8.6e-05 22.2 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) TMEM154 PF15102.1 EPE31720.1 - 0.001 18.7 0.2 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family Mem_trans PF03547.13 EPE31720.1 - 0.001 17.4 0.0 0.001 17.4 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein ASFV_J13L PF05568.6 EPE31720.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein Herpes_gE PF02480.11 EPE31720.1 - 0.0012 17.2 0.0 0.0013 17.1 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E CD34_antigen PF06365.7 EPE31720.1 - 0.0015 18.2 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family AA_permease_2 PF13520.1 EPE31720.1 - 0.0024 16.4 0.2 0.003 16.1 0.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF912 PF06024.7 EPE31720.1 - 0.0029 17.6 0.2 0.0029 17.6 0.1 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EPE31720.1 - 0.0032 17.1 7.6 0.0048 16.5 5.2 1.2 1 0 0 1 1 1 1 Rifin/stevor family DUF3816 PF12822.2 EPE31720.1 - 0.0079 16.1 0.1 0.0079 16.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) EphA2_TM PF14575.1 EPE31720.1 - 0.0084 16.4 5.6 0.033 14.5 3.3 2.4 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF4330 PF14221.1 EPE31720.1 - 0.0085 15.9 1.8 0.26 11.1 0.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4330) Tetraspannin PF00335.15 EPE31720.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF3169 PF11368.3 EPE31720.1 - 0.015 14.5 1.2 0.019 14.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF443 PF04276.7 EPE31720.1 - 0.017 14.5 0.6 0.022 14.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) YajC PF02699.10 EPE31720.1 - 0.019 14.6 0.9 0.029 14.0 0.3 1.5 2 0 0 2 2 1 0 Preprotein translocase subunit Adeno_E3_CR2 PF02439.10 EPE31720.1 - 0.02 14.4 7.4 0.035 13.6 5.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3753 PF12575.3 EPE31720.1 - 0.028 14.2 3.7 0.046 13.5 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF3792 PF12670.2 EPE31720.1 - 0.028 14.2 0.8 0.038 13.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) DUF2970 PF11174.3 EPE31720.1 - 0.032 13.7 2.2 0.05 13.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) UPF0104 PF03706.8 EPE31720.1 - 0.036 13.3 1.0 0.043 13.1 0.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF3609 PF12259.3 EPE31720.1 - 0.036 12.7 0.1 0.041 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Amnionless PF14828.1 EPE31720.1 - 0.039 12.4 0.0 0.04 12.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless Chordopox_A33R PF05966.7 EPE31720.1 - 0.042 12.6 1.2 0.054 12.2 0.6 1.3 1 1 0 1 1 1 0 Chordopoxvirus A33R protein DUF3328 PF11807.3 EPE31720.1 - 0.045 13.4 0.0 0.056 13.1 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) DUF2561 PF10812.3 EPE31720.1 - 0.05 13.1 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) PrgH PF09480.5 EPE31720.1 - 0.053 12.3 0.1 0.067 12.0 0.1 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) TMEM192 PF14802.1 EPE31720.1 - 0.068 12.0 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 TMEM192 family Mid2 PF04478.7 EPE31720.1 - 0.073 12.4 0.4 0.099 12.0 0.3 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3377 PF11857.3 EPE31720.1 - 0.077 12.6 0.6 0.15 11.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) SIT PF15330.1 EPE31720.1 - 0.08 13.0 3.4 0.07 13.2 1.1 1.9 2 1 0 2 2 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF1980 PF09323.5 EPE31720.1 - 0.1 12.3 0.1 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Neur_chan_memb PF02932.11 EPE31720.1 - 0.11 12.3 0.3 0.2 11.5 0.2 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4446 PF14584.1 EPE31720.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Claudin_2 PF13903.1 EPE31720.1 - 0.14 11.8 0.2 0.14 11.8 0.1 1.4 2 0 0 2 2 1 0 PMP-22/EMP/MP20/Claudin tight junction Chloroa_b-bind PF00504.16 EPE31720.1 - 0.15 12.3 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyll A-B binding protein Protocadherin PF08374.6 EPE31720.1 - 0.15 11.6 4.8 0.19 11.3 3.3 1.3 1 1 0 1 1 1 0 Protocadherin Sigma_reg_N PF13800.1 EPE31720.1 - 0.16 12.0 3.4 0.33 11.0 2.3 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3112 PF11309.3 EPE31720.1 - 0.2 11.4 3.3 0.21 11.3 1.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) DUF202 PF02656.10 EPE31720.1 - 0.21 11.8 0.6 0.29 11.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) LRR19-TM PF15176.1 EPE31720.1 - 0.22 11.2 1.6 0.27 10.9 1.1 1.4 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Baculo_E56 PF04639.7 EPE31720.1 - 0.22 10.1 1.6 0.29 9.7 1.1 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope LRRC37AB_C PF14914.1 EPE31720.1 - 0.25 10.7 1.5 0.35 10.2 1.0 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Gemini_mov PF01708.11 EPE31720.1 - 0.25 10.8 2.0 0.41 10.2 0.0 2.2 2 1 0 2 2 2 0 Geminivirus putative movement protein NfeD PF01957.13 EPE31720.1 - 0.26 11.4 3.1 1.1 9.4 2.2 1.8 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4381 PF14316.1 EPE31720.1 - 0.31 11.1 0.1 0.31 11.1 0.1 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4381) DUF1049 PF06305.6 EPE31720.1 - 0.36 10.3 3.3 0.46 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) EzrA PF06160.7 EPE31720.1 - 0.42 8.7 4.3 0.58 8.2 3.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF2615 PF11027.3 EPE31720.1 - 0.51 10.2 2.2 0.67 9.9 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2615) Podoplanin PF05808.6 EPE31720.1 - 0.63 9.5 2.2 0.89 9.0 1.5 1.2 1 0 0 1 1 1 0 Podoplanin DUF3357 PF11837.3 EPE31720.1 - 0.66 9.8 2.8 0.72 9.7 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Wzy_C PF04932.10 EPE31720.1 - 1.3 8.7 6.1 3.2 7.5 4.2 1.7 1 1 0 1 1 1 0 O-Antigen ligase Synaptobrevin PF00957.16 EPE31720.1 - 1.6 8.3 4.3 2.8 7.5 3.0 1.4 1 0 0 1 1 1 0 Synaptobrevin DUF2393 PF09624.5 EPE31720.1 - 2.3 7.7 6.5 0.16 11.4 1.1 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2393) DUF3139 PF11337.3 EPE31720.1 - 3.9 7.8 7.0 5.8 7.2 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) Vpu PF00558.14 EPE31720.1 - 5.1 6.7 8.4 6.2 6.4 5.4 1.5 1 1 1 2 2 1 0 Vpu protein O-antigen_lig PF13425.1 EPE31720.1 - 6.4 6.7 9.1 13 5.7 6.3 1.7 1 1 0 1 1 1 0 O-antigen ligase like membrane protein RELT PF12606.3 EPE31720.1 - 6.4 5.9 9.3 15 4.8 6.5 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF4066 PF13278.1 EPE31721.1 - 1e-24 86.7 0.0 1.5e-20 73.1 0.0 2.0 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EPE31721.1 - 1.6e-07 30.8 0.0 3.7e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family SNO PF01174.14 EPE31721.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Mito_carr PF00153.22 EPE31722.1 - 4.9e-49 163.9 6.4 2.4e-17 62.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein APH PF01636.18 EPE31723.1 - 5.4e-12 45.9 0.0 5.4e-11 42.6 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EPE31723.1 - 0.012 14.3 0.6 0.9 8.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1679) NOC3p PF07540.6 EPE31724.1 - 4.8e-34 116.5 0.2 1.5e-33 114.9 0.1 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 EPE31724.1 - 8.3e-28 96.8 0.0 2.1e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 CBF/Mak21 family UPF0113 PF03657.8 EPE31725.1 - 1.4e-06 28.0 0.0 1.8e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EPE31725.1 - 0.035 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 PUA domain Methyltransf_2 PF00891.13 EPE31726.1 - 1e-16 60.8 0.0 1.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase DEAD PF00270.24 EPE31727.1 - 6.3e-33 113.6 0.0 1.5e-32 112.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE31727.1 - 3e-17 62.2 0.0 6e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE31727.1 - 0.00029 20.7 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPE31727.1 - 0.11 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF77 PF01910.12 EPE31730.1 - 4.2e-30 103.2 0.0 5.1e-30 102.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 DUF3328 PF11807.3 EPE31731.1 - 4.3e-30 105.0 1.0 5.5e-30 104.6 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PHP_C PF13263.1 EPE31732.1 - 0.046 13.2 1.6 10 5.7 0.0 3.7 2 1 3 5 5 5 0 PHP-associated Methyltransf_2 PF00891.13 EPE31733.1 - 5.5e-35 120.7 0.0 7e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EPE31733.1 - 7.6e-05 22.4 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE31733.1 - 0.0027 18.2 0.0 0.011 16.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE31733.1 - 0.005 16.4 0.0 0.036 13.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE31733.1 - 0.0054 17.1 0.0 0.013 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EPE31733.1 - 0.061 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF3328 PF11807.3 EPE31734.1 - 6.7e-28 97.8 0.0 1.3e-27 96.8 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Tyrosinase PF00264.15 EPE31735.1 - 2e-32 113.1 0.3 2.9e-32 112.6 0.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase p450 PF00067.17 EPE31736.1 - 3e-57 194.1 0.0 3.9e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3796 PF12676.2 EPE31737.1 - 6.8 6.9 8.0 4.3 7.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) RRP7 PF12923.2 EPE31738.1 - 0.052 13.5 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) DUF3945 PF13101.1 EPE31739.1 - 0.044 13.0 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) CorA PF01544.13 EPE31740.1 - 1.4e-11 43.9 7.2 2.1e-10 40.1 5.0 2.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein bZIP_1 PF00170.16 EPE31740.1 - 1.3e-06 28.2 2.3 2.3e-06 27.4 0.9 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EPE31740.1 - 0.00021 21.0 3.4 0.00021 21.0 2.3 2.7 3 0 0 3 3 3 1 Basic region leucine zipper Striatin PF08232.7 EPE31740.1 - 0.0045 17.2 0.5 0.0045 17.2 0.3 2.4 2 1 1 3 3 3 1 Striatin family Syntaxin_2 PF14523.1 EPE31740.1 - 0.011 15.6 1.9 0.064 13.2 0.0 2.8 3 0 0 3 3 3 0 Syntaxin-like protein TPD52 PF04201.10 EPE31740.1 - 0.044 13.4 0.2 0.12 12.0 0.1 1.8 1 0 0 1 1 1 0 Tumour protein D52 family WD40_alt PF14077.1 EPE31740.1 - 0.2 11.3 4.0 0.15 11.6 0.5 2.5 3 0 0 3 3 3 0 Alternative WD40 repeat motif bZIP_Maf PF03131.12 EPE31740.1 - 0.82 10.0 7.5 0.036 14.3 1.0 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF972 PF06156.8 EPE31740.1 - 9.9 6.5 6.2 69 3.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Sigma70_r4_2 PF08281.7 EPE31741.1 - 0.034 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 AAA_5 PF07728.9 EPE31743.1 - 1.9e-122 403.4 0.0 5.1e-21 74.8 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPE31743.1 - 4.1e-28 97.6 0.0 8.1e-11 41.6 0.0 7.9 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EPE31743.1 - 1.9e-27 96.0 0.0 0.00034 20.8 0.0 7.0 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE31743.1 - 1.6e-25 90.2 0.0 0.0015 19.3 0.0 7.7 6 1 0 6 6 6 5 AAA domain AAA_22 PF13401.1 EPE31743.1 - 4.9e-25 88.1 3.0 0.05 13.7 0.0 9.6 9 1 0 9 9 7 6 AAA domain AAA_33 PF13671.1 EPE31743.1 - 8.6e-25 87.2 0.0 0.002 18.0 0.0 7.3 6 0 0 6 6 6 6 AAA domain AAA_16 PF13191.1 EPE31743.1 - 3.8e-21 75.9 23.2 0.00076 19.5 0.1 8.4 8 1 0 8 8 6 5 AAA ATPase domain AAA_14 PF13173.1 EPE31743.1 - 1e-20 73.9 0.0 0.00095 19.0 0.0 7.3 6 0 0 6 6 6 3 AAA domain Sigma54_activ_2 PF14532.1 EPE31743.1 - 3.1e-20 72.6 0.3 0.00016 21.7 0.0 8.3 7 0 0 7 7 7 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EPE31743.1 - 3.8e-20 72.0 0.2 0.04 13.3 0.0 6.6 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_18 PF13238.1 EPE31743.1 - 9.6e-20 71.2 0.3 0.021 15.1 0.0 7.2 6 0 0 6 6 6 4 AAA domain T2SE PF00437.15 EPE31743.1 - 6.7e-18 64.5 0.1 0.052 12.4 0.0 6.5 6 0 0 6 6 6 5 Type II/IV secretion system protein NACHT PF05729.7 EPE31743.1 - 4e-17 62.3 2.6 0.055 13.1 0.0 6.3 6 0 0 6 6 5 5 NACHT domain ABC_tran PF00005.22 EPE31743.1 - 3.2e-15 56.6 4.9 0.024 14.9 0.0 7.5 7 0 0 7 7 7 3 ABC transporter AAA_19 PF13245.1 EPE31743.1 - 2.7e-14 52.6 6.2 0.0019 17.9 0.0 6.7 6 0 0 6 6 6 3 Part of AAA domain Zeta_toxin PF06414.7 EPE31743.1 - 3.4e-14 52.4 2.9 0.48 9.5 0.0 7.4 7 0 0 7 7 7 3 Zeta toxin UPF0079 PF02367.12 EPE31743.1 - 3.6e-14 52.4 3.6 0.015 14.9 0.0 6.2 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EPE31743.1 - 1.2e-13 51.1 1.5 0.12 12.5 0.0 7.0 6 0 0 6 6 6 2 RNA helicase AAA_29 PF13555.1 EPE31743.1 - 5.1e-13 48.3 0.3 0.35 10.4 0.0 6.5 6 0 0 6 6 6 2 P-loop containing region of AAA domain Miro PF08477.8 EPE31743.1 - 1.8e-12 47.8 0.8 2.5 8.6 0.0 7.0 6 0 0 6 6 6 1 Miro-like protein MobB PF03205.9 EPE31743.1 - 3.4e-12 46.2 3.9 0.73 9.5 0.0 6.8 7 0 0 7 7 6 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EPE31743.1 - 3.9e-12 45.6 2.6 0.26 10.4 0.1 5.9 6 0 0 6 6 6 3 Protein of unknown function, DUF258 AAA_28 PF13521.1 EPE31743.1 - 5.1e-12 46.0 4.2 0.094 12.6 0.0 7.1 7 0 0 7 7 6 2 AAA domain Arch_ATPase PF01637.13 EPE31743.1 - 6.8e-12 45.5 0.0 0.0087 15.7 0.0 6.7 6 0 0 6 6 6 1 Archaeal ATPase AAA_25 PF13481.1 EPE31743.1 - 8.7e-11 41.5 0.4 1.2 8.5 0.1 5.9 5 0 0 5 5 5 4 AAA domain SRP54 PF00448.17 EPE31743.1 - 1.3e-10 41.0 0.8 1.1 8.6 0.0 6.3 7 0 0 7 7 5 3 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 EPE31743.1 - 1.5e-09 37.5 1.5 0.035 13.6 0.0 5.7 6 0 0 6 6 6 3 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.7 EPE31743.1 - 3.5e-09 36.0 4.4 0.086 11.8 0.0 6.4 7 0 0 7 7 7 2 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EPE31743.1 - 6.4e-09 35.6 0.1 0.24 10.8 0.0 6.1 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 EPE31743.1 - 6.1e-08 32.2 0.2 0.43 9.9 0.0 5.4 5 0 0 5 5 5 1 IstB-like ATP binding protein cobW PF02492.14 EPE31743.1 - 2.6e-07 30.2 4.9 0.044 13.2 0.1 5.8 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EPE31743.1 - 3.4e-07 30.1 5.2 0.46 10.1 0.0 6.2 6 0 0 6 6 6 2 NTPase AAA_24 PF13479.1 EPE31743.1 - 1.9e-06 27.6 0.2 9.6 5.7 0.0 6.1 6 0 0 6 6 6 0 AAA domain FtsK_SpoIIIE PF01580.13 EPE31743.1 - 4.4e-06 26.3 1.5 4 6.8 0.0 5.7 6 0 0 6 6 6 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EPE31743.1 - 1e-05 25.4 1.7 4.7 7.2 0.0 6.3 6 0 0 6 6 6 0 50S ribosome-binding GTPase AAA_7 PF12775.2 EPE31743.1 - 9e-05 21.6 1.8 2.8 6.9 0.0 4.6 5 0 0 5 5 4 1 P-loop containing dynein motor region D3 Rad17 PF03215.10 EPE31743.1 - 0.00021 20.1 0.1 0.96 8.0 0.0 4.2 4 0 0 4 4 4 1 Rad17 cell cycle checkpoint protein AAA_6 PF12774.2 EPE31743.1 - 0.00032 20.2 0.0 8.1 5.8 0.0 5.6 6 0 0 6 6 6 0 Hydrolytic ATP binding site of dynein motor region D1 ATP_bind_1 PF03029.12 EPE31743.1 - 0.00061 19.3 5.5 29 4.1 0.0 6.4 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein TIP49 PF06068.8 EPE31743.1 - 0.00075 18.3 1.2 20 3.7 0.0 5.0 6 0 0 6 6 5 0 TIP49 C-terminus KaiC PF06745.8 EPE31743.1 - 0.00091 18.3 0.4 12 4.8 0.0 5.1 5 0 0 5 5 5 0 KaiC AAA_23 PF13476.1 EPE31743.1 - 0.0013 19.0 29.3 0.46 10.7 0.0 9.0 9 0 0 9 9 7 2 AAA domain AAA_21 PF13304.1 EPE31743.1 - 0.0014 18.6 0.4 7 6.5 0.0 5.2 5 0 0 5 5 5 0 AAA domain PhoH PF02562.11 EPE31743.1 - 0.0027 16.9 0.3 8.7 5.5 0.0 5.2 5 0 0 5 5 5 0 PhoH-like protein ATP-synt_ab PF00006.20 EPE31743.1 - 0.0038 16.7 0.0 5.4 6.4 0.0 4.3 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 EPE31743.1 - 0.0049 15.9 0.0 2.3 7.1 0.0 4.3 5 0 0 5 5 5 1 AAA ATPase domain PRK PF00485.13 EPE31743.1 - 0.0053 16.3 1.4 7.7 6.0 0.0 4.9 6 0 0 6 6 4 0 Phosphoribulokinase / Uridine kinase family CbiA PF01656.18 EPE31743.1 - 0.037 13.4 5.4 8 5.8 0.0 4.2 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ras PF00071.17 EPE31743.1 - 0.82 9.0 3.1 1.1e+02 2.1 0.0 4.4 5 0 0 5 5 5 0 Ras family Ribosomal_L12 PF00542.14 EPE31744.1 - 1.6e-18 66.4 4.2 1.5e-17 63.3 2.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain CTK3 PF12243.3 EPE31745.1 - 2.6e-60 202.0 1.4 3.7e-60 201.5 1.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EPE31745.1 - 9.6e-22 76.7 8.9 9.6e-22 76.7 6.2 2.2 3 0 0 3 3 3 1 CTD kinase subunit gamma CTK3 C-terminus DUF3873 PF12989.2 EPE31745.1 - 0.12 12.4 0.1 0.63 10.2 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3873) P5CR_dimer PF14748.1 EPE31746.1 - 5e-35 119.7 4.0 9.2e-35 118.8 2.8 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EPE31746.1 - 1.3e-15 57.5 0.0 4.4e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Hat1_N PF10394.4 EPE31747.1 - 2.2e-39 135.0 0.2 3.9e-39 134.3 0.1 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Zip PF02535.17 EPE31748.1 - 5.3e-42 143.9 7.2 8.5e-41 139.9 5.0 2.4 1 1 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.16 EPE31748.1 - 0.29 10.1 6.9 3.5 6.5 4.7 2.5 3 0 0 3 3 3 0 Cation efflux family WD40 PF00400.27 EPE31749.1 - 5.2e-53 175.1 16.1 6.3e-10 38.5 0.2 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EPE31749.1 - 2.7e-10 39.7 0.8 4.8e-10 39.0 0.6 1.4 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EPE31749.1 - 1.9e-09 36.2 6.7 0.0021 16.2 0.5 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.28 EPE31749.1 - 0.00013 21.5 0.7 0.00025 20.5 0.5 1.5 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EPE31749.1 - 0.0062 15.3 0.4 0.21 10.3 0.0 2.8 1 1 2 4 4 4 1 Nup133 N terminal like PQQ_3 PF13570.1 EPE31749.1 - 0.042 14.1 1.7 34 4.9 0.0 4.9 5 2 0 5 5 5 0 PQQ-like domain E1_dh PF00676.15 EPE31750.1 - 1.2e-114 382.0 0.3 1.5e-114 381.8 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EPE31750.1 - 2.8e-05 23.1 0.0 4.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EPE31750.1 - 0.023 14.2 1.7 0.046 13.3 1.2 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Asp PF00026.18 EPE31751.1 - 1e-06 28.2 0.2 4.7e-06 26.0 0.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPE31751.1 - 0.036 14.0 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal SKG6 PF08693.5 EPE31751.1 - 0.35 10.2 3.1 1.2 8.4 2.2 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ank_2 PF12796.2 EPE31753.1 - 1.1e-35 121.8 3.2 8.8e-19 67.6 0.9 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE31753.1 - 4.7e-35 117.6 5.3 5.1e-09 35.5 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 EPE31753.1 - 3.3e-27 91.8 1.4 2.4e-06 27.2 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EPE31753.1 - 2.1e-26 91.7 9.5 6.9e-08 32.7 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE31753.1 - 4.7e-22 77.5 3.9 1.9e-06 27.9 0.1 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) CTD_bind PF04818.8 EPE31756.1 - 1.5e-22 79.5 0.3 2.9e-22 78.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3277 PF11681.3 EPE31756.1 - 0.0012 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) CTK3 PF12243.3 EPE31756.1 - 0.0074 15.9 0.2 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 LepA_C PF06421.7 EPE31756.1 - 0.13 12.1 0.2 1.3 9.0 0.1 2.2 1 1 1 2 2 2 0 GTP-binding protein LepA C-terminus COX7a PF02238.10 EPE31757.1 - 0.35 10.6 6.4 3.8 7.3 4.5 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIa PPR_3 PF13812.1 EPE31758.1 - 0.032 14.5 0.0 1.5 9.3 0.0 3.7 5 0 0 5 5 5 0 Pentatricopeptide repeat domain DUF2975 PF11188.3 EPE31759.1 - 1.2 8.8 8.6 0.11 12.1 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) EHN PF06441.7 EPE31760.1 - 6.5e-31 106.5 0.1 1e-30 105.9 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EPE31760.1 - 1.3e-11 44.8 0.0 2.7e-11 43.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE31760.1 - 7.7e-10 38.7 0.0 1.7e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE31760.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family CTP_transf_2 PF01467.21 EPE31761.1 - 2.3e-24 86.2 0.0 2.9e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase APH PF01636.18 EPE31762.1 - 1.2e-07 31.7 0.0 0.00037 20.3 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Aldo_ket_red PF00248.16 EPE31763.1 - 3e-55 187.0 0.0 3.5e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1929 PF09118.6 EPE31765.1 - 2.8e-24 85.0 0.7 1.2e-23 83.0 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.20 EPE31765.1 - 1.2e-20 73.5 1.9 3.4e-20 72.2 1.3 1.8 1 0 0 1 1 1 1 F5/8 type C domain Kelch_1 PF01344.20 EPE31765.1 - 3e-05 23.4 0.3 0.27 10.8 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 EPE31765.1 - 4.7e-05 23.3 10.4 1.2 9.3 0.0 5.7 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.1 EPE31765.1 - 7e-05 22.5 6.8 0.33 10.7 0.2 5.6 5 1 0 5 5 5 2 Galactose oxidase, central domain PD40 PF07676.7 EPE31765.1 - 0.0022 17.6 0.4 0.03 13.9 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Glyoxal_oxid_N PF07250.6 EPE31765.1 - 0.011 14.8 0.2 0.54 9.2 0.0 2.9 3 0 0 3 3 3 0 Glyoxal oxidase N-terminus Glycos_transf_1 PF00534.15 EPE31766.1 - 2.5e-11 43.2 0.0 8.5e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF3492 PF11997.3 EPE31766.1 - 6.5e-05 22.6 0.0 0.00039 20.0 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 EPE31766.1 - 0.00054 20.1 0.1 0.0023 18.0 0.1 2.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Spherulin4 PF12138.3 EPE31767.1 - 3.6e-58 196.9 0.0 4.1e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 DUF4127 PF13552.1 EPE31767.1 - 0.16 10.3 0.1 0.23 9.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) Spherulin4 PF12138.3 EPE31768.1 - 2.3e-60 204.1 0.0 2.5e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Epimerase PF01370.16 EPE31769.1 - 7.6e-36 123.7 0.0 1.8e-35 122.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EPE31769.1 - 7.2e-13 48.2 0.0 1.4e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NAD_binding_4 PF07993.7 EPE31769.1 - 8.3e-09 34.7 0.0 3e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EPE31769.1 - 7.3e-08 31.6 0.0 3.4e-05 22.8 0.0 3.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPE31769.1 - 1.8e-07 30.1 0.0 0.00011 20.9 0.0 2.5 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EPE31769.1 - 3.7e-05 23.4 0.0 0.00012 21.8 0.0 1.8 1 1 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.9 EPE31769.1 - 0.002 17.5 0.2 0.027 13.8 0.0 2.4 2 1 1 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.20 EPE31769.1 - 0.0025 17.7 0.0 0.015 15.2 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EPE31769.1 - 0.059 13.3 0.0 7.3 6.5 0.0 2.5 2 1 0 2 2 2 0 NADH(P)-binding APH PF01636.18 EPE31771.1 - 3.3e-15 56.4 0.0 5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE31771.1 - 0.00016 21.3 0.4 0.00029 20.4 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 EPE31771.1 - 0.00092 18.6 0.1 0.04 13.2 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 EPE31771.1 - 0.042 13.0 0.0 0.26 10.4 0.0 2.1 2 1 0 2 2 2 0 Protein kinase domain HET PF06985.6 EPE31772.1 - 8.2e-28 97.3 0.0 1.3e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GSDH PF07995.6 EPE31773.1 - 1.2e-08 34.4 1.1 4.3e-07 29.3 0.8 2.8 1 1 1 2 2 2 2 Glucose / Sorbosone dehydrogenase SGL PF08450.7 EPE31773.1 - 0.00052 19.4 0.1 0.0072 15.7 0.0 2.6 3 1 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EPE31773.1 - 0.015 15.2 0.0 46 4.2 0.0 4.5 3 1 1 4 4 4 0 NHL repeat FtsJ PF01728.14 EPE31774.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase FBD PF08387.5 EPE31775.1 - 0.069 12.6 0.3 0.13 11.7 0.2 1.5 1 0 0 1 1 1 0 FBD BTB PF00651.26 EPE31778.1 - 3.4e-07 30.2 0.0 9.6e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Stm1_N PF09598.5 EPE31779.1 - 4.4e-11 43.3 5.7 4.4e-11 43.3 4.0 4.2 4 0 0 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.10 EPE31779.1 - 2.6e-07 31.0 1.8 2.6e-07 31.0 1.3 3.6 3 3 1 4 4 4 1 Hyaluronan / mRNA binding family bZIP_1 PF00170.16 EPE31780.1 - 4.9e-06 26.3 6.5 8.2e-06 25.6 4.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor GvpL_GvpF PF06386.6 EPE31780.1 - 0.08 12.5 2.2 0.16 11.5 1.5 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.10 EPE31780.1 - 0.082 12.7 5.6 0.18 11.6 3.9 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DUF4407 PF14362.1 EPE31780.1 - 0.41 9.5 2.3 0.61 8.9 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LIM PF00412.17 EPE31782.1 - 8e-05 22.6 3.8 0.00016 21.6 0.7 2.5 2 0 0 2 2 2 1 LIM domain Med10 PF09748.4 EPE31783.1 - 1.1e-34 118.9 0.0 1.3e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex KAR PF15222.1 EPE31783.1 - 0.083 12.9 0.1 0.19 11.8 0.1 1.6 2 0 0 2 2 2 0 Kidney androgen-regulated EF-hand_2 PF09068.6 EPE31783.1 - 0.096 12.7 0.1 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 EF hand p450 PF00067.17 EPE31784.1 - 2e-50 171.6 0.0 3.5e-50 170.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EPE31785.1 - 3.3e-23 81.7 3.9 7.8e-23 80.4 2.7 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE31785.1 - 0.007 16.2 0.7 0.018 14.9 0.5 1.7 1 0 0 1 1 1 1 Berberine and berberine like Ndc80_HEC PF03801.8 EPE31785.1 - 0.19 11.1 0.0 0.6 9.5 0.0 1.8 1 1 0 1 1 1 0 HEC/Ndc80p family MFS_1 PF07690.11 EPE31788.1 - 5.2e-45 153.6 45.4 9.6e-45 152.8 31.5 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE31788.1 - 1.4e-09 37.1 8.9 1.4e-09 37.1 6.2 3.0 1 1 1 3 3 3 1 Sugar (and other) transporter WD40 PF00400.27 EPE31789.1 - 0.088 12.7 0.3 36 4.4 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF2361 PF10153.4 EPE31790.1 - 3.7e-37 126.9 6.9 3.7e-37 126.9 4.8 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) DUF1075 PF06388.6 EPE31790.1 - 0.36 10.4 5.3 0.089 12.4 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) Matrilin_ccoil PF10393.4 EPE31790.1 - 0.64 9.4 4.2 3 7.2 0.0 3.0 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin dsrm PF00035.20 EPE31791.1 - 7.5e-06 26.4 0.0 0.00015 22.2 0.0 2.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EPE31791.1 - 0.038 14.2 0.1 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 double strand RNA binding domain from DEAD END PROTEIN 1 Transketolase_N PF00456.16 EPE31791.1 - 0.07 11.9 0.3 0.32 9.7 0.0 1.9 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain PTS_2-RNA PF01885.11 EPE31792.1 - 1.1e-64 217.1 0.0 1.4e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 EPE31792.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 La domain DSPc PF00782.15 EPE31794.1 - 8.8e-21 73.8 0.0 2.9e-18 65.7 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPE31794.1 - 0.0012 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EPE31794.1 - 0.0073 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EPE31794.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Formyl_trans_N PF00551.14 EPE31797.1 - 1.2e-38 132.5 0.0 1.4e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase HTHP PF11534.3 EPE31797.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Hexameric tyrosine-coordinated heme protein (HTHP) Pkinase PF00069.20 EPE31798.1 - 1.1e-47 162.3 0.0 1.8e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE31798.1 - 1.4e-24 86.5 0.0 2.1e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE31798.1 - 1.7e-09 37.1 0.0 2.5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPE31798.1 - 0.00031 20.5 0.5 0.049 13.3 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EPE31798.1 - 0.0065 15.5 0.0 0.016 14.2 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EPE31798.1 - 0.068 12.0 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 MDM31_MDM32 PF08118.6 EPE31799.1 - 6.2e-193 641.8 1.6 7.4e-193 641.5 1.1 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.6 EPE31799.1 - 0.0086 15.5 0.1 0.02 14.3 0.1 1.6 1 0 0 1 1 1 1 TraH_2 KH_1 PF00013.24 EPE31800.1 - 0.00014 21.4 1.6 0.00029 20.4 1.1 1.5 1 0 0 1 1 1 1 KH domain HSP20 PF00011.16 EPE31801.1 - 2.5e-14 52.9 0.1 6.4e-09 35.5 0.0 2.5 1 1 1 2 2 2 2 Hsp20/alpha crystallin family DUF4148 PF13663.1 EPE31801.1 - 0.067 13.0 0.4 0.3 10.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF1777 PF08648.7 EPE31801.1 - 0.2 11.3 18.7 0.4 10.4 13.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Corona_nucleoca PF00937.13 EPE31801.1 - 0.31 9.9 6.6 0.47 9.3 4.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein YTH PF04146.10 EPE31802.1 - 3.2e-58 195.2 0.0 5e-58 194.6 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Pkinase PF00069.20 EPE31803.1 - 2e-57 194.2 0.0 2.8e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE31803.1 - 2.7e-20 72.5 0.0 4e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE31803.1 - 3.1e-08 32.9 0.0 5.8e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPE31803.1 - 0.0001 21.4 0.1 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE31803.1 - 0.00013 21.8 0.4 0.026 14.2 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EPE31803.1 - 0.0058 16.0 0.3 0.014 14.7 0.2 1.6 1 1 0 1 1 1 1 RIO1 family DUF2207 PF09972.4 EPE31805.1 - 0.23 9.9 2.4 0.27 9.7 1.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 EPE31805.1 - 0.65 9.3 4.8 0.98 8.8 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1700 PF08006.6 EPE31805.1 - 0.98 8.6 4.9 1.3 8.2 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Ank_2 PF12796.2 EPE31806.1 - 7e-84 276.2 16.8 8e-14 51.7 0.8 8.8 4 2 5 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EPE31806.1 - 5.3e-65 212.1 18.3 0.00032 20.3 0.1 18.2 19 1 0 19 19 19 14 Ankyrin repeat Ank_4 PF13637.1 EPE31806.1 - 2.4e-54 180.8 16.0 9.5e-06 25.9 0.1 14.7 9 4 6 15 15 15 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE31806.1 - 1.8e-45 151.9 17.6 1.4e-05 25.1 0.0 12.0 6 3 5 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE31806.1 - 9.2e-44 143.0 9.4 0.058 13.6 0.0 18.3 18 0 0 18 18 18 11 Ankyrin repeat F-box-like PF12937.2 EPE31806.1 - 0.0017 18.0 0.2 0.005 16.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like Methyltransf_23 PF13489.1 EPE31807.1 - 1.3e-10 41.2 0.0 3.9e-10 39.6 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE31807.1 - 1.7e-09 38.0 0.0 3.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE31807.1 - 4.9e-09 36.7 0.0 3.8e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE31807.1 - 1.3e-08 35.2 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE31807.1 - 2.5e-06 27.1 0.0 3.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE31807.1 - 1.3e-05 25.4 0.0 2.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EPE31807.1 - 0.001 18.0 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 EPE31807.1 - 0.0024 17.2 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EPE31807.1 - 0.0025 17.8 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EPE31807.1 - 0.0026 17.3 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.12 EPE31807.1 - 0.016 14.2 0.0 0.032 13.2 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.14 EPE31807.1 - 0.05 13.5 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EPE31807.1 - 0.091 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.4 EPE31807.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Isochorismatase PF00857.15 EPE31808.1 - 2.9e-20 72.9 0.0 4.2e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family ABC_tran PF00005.22 EPE31810.1 - 7.4e-51 172.0 0.0 2e-26 92.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPE31810.1 - 1.4e-28 100.0 37.1 4.1e-22 78.8 14.6 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EPE31810.1 - 1.4e-13 51.4 0.4 0.064 13.2 0.1 4.5 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 EPE31810.1 - 1.5e-09 37.4 5.0 0.019 14.1 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EPE31810.1 - 3.9e-07 30.2 0.1 0.038 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 EPE31810.1 - 1e-06 27.8 0.6 0.00036 19.5 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 EPE31810.1 - 1.3e-06 28.5 0.1 0.0091 16.1 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPE31810.1 - 2.8e-06 26.7 0.9 0.028 13.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EPE31810.1 - 3.7e-05 24.1 0.1 0.13 12.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 EPE31810.1 - 3.8e-05 23.2 0.8 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 EPE31810.1 - 0.00037 19.9 0.1 0.66 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EPE31810.1 - 0.00043 20.6 3.0 0.039 14.2 0.2 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EPE31810.1 - 0.00046 19.4 2.0 0.21 10.7 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EPE31810.1 - 0.0008 19.3 0.2 0.55 10.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EPE31810.1 - 0.00081 19.2 0.0 0.18 11.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPE31810.1 - 0.0017 19.1 1.2 2.6 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPE31810.1 - 0.0024 17.5 2.2 0.33 10.6 0.1 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EPE31810.1 - 0.0028 17.5 0.5 0.89 9.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 EPE31810.1 - 0.0028 17.1 3.6 0.19 11.1 0.4 2.5 2 0 0 2 2 2 1 AAA-like domain cobW PF02492.14 EPE31810.1 - 0.0035 16.7 1.9 0.015 14.7 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EPE31810.1 - 0.0039 16.9 0.6 0.058 13.0 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 EPE31810.1 - 0.0039 16.2 0.0 0.3 10.1 0.0 2.5 3 0 0 3 3 2 1 Zeta toxin AAA_18 PF13238.1 EPE31810.1 - 0.007 16.6 0.2 4.4 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EPE31810.1 - 0.0083 15.7 0.6 0.8 9.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Pox_A32 PF04665.7 EPE31810.1 - 0.0093 15.2 0.7 1.6 7.9 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_14 PF13173.1 EPE31810.1 - 0.014 15.2 0.0 0.39 10.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 EPE31810.1 - 0.015 15.4 0.2 4.2 7.5 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EPE31810.1 - 0.015 14.9 0.6 0.54 9.8 0.1 2.6 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 EPE31810.1 - 0.022 14.2 1.3 2.3 7.6 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 EPE31810.1 - 0.025 14.4 3.2 0.091 12.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 Sigma54_activat PF00158.21 EPE31810.1 - 0.025 14.0 0.0 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 EPE31810.1 - 0.048 13.4 0.6 0.56 9.9 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 EPE31810.1 - 0.056 13.0 0.8 7.1 6.1 0.1 3.2 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EPE31810.1 - 0.061 12.8 2.0 0.8 9.2 0.2 2.6 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EPE31810.1 - 0.071 12.6 0.0 0.71 9.3 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.13 EPE31810.1 - 0.081 11.9 0.3 2 7.3 0.0 2.1 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.10 EPE31810.1 - 0.09 12.4 1.0 6.1 6.5 0.2 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 EPE31810.1 - 0.12 11.8 0.7 0.83 9.1 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TrwB_AAD_bind PF10412.4 EPE31810.1 - 0.15 10.6 0.9 1.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 EPE31810.1 - 0.2 11.8 0.0 41 4.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 EPE31810.1 - 0.24 11.1 1.0 14 5.3 0.1 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) DUF2513 PF10711.4 EPE31811.1 - 0.058 13.4 0.0 0.27 11.3 0.0 2.1 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) Pyr_redox_3 PF13738.1 EPE31812.1 - 0.17 11.9 0.5 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PIP5K PF01504.13 EPE31814.1 - 2.4e-60 203.7 0.3 4.6e-60 202.8 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EPE31814.1 - 1.1e-27 96.7 0.0 2e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EPE31814.1 - 5.7e-12 45.3 10.3 1.6e-11 43.8 7.1 1.8 1 0 0 1 1 1 1 FYVE zinc finger tRNA_anti-codon PF01336.20 EPE31814.1 - 0.23 11.3 0.0 0.62 9.9 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain FYVE_2 PF02318.11 EPE31814.1 - 1.3 8.9 11.7 0.098 12.5 4.0 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger ABC2_membrane PF01061.19 EPE31815.1 - 2.2e-38 131.5 23.1 3.9e-38 130.7 16.0 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EPE31815.1 - 5.4e-25 88.2 0.0 9.4e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPE31815.1 - 1.2e-08 35.2 0.0 1.3e-06 28.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EPE31815.1 - 3.3e-07 29.6 27.6 3.3e-07 29.6 19.1 2.2 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_25 PF13481.1 EPE31815.1 - 0.0031 16.9 0.0 0.22 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EPE31815.1 - 0.015 14.5 0.3 0.035 13.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 hEGF PF12661.2 EPE31815.1 - 0.019 15.0 23.4 0.057 13.5 4.3 4.0 3 0 0 3 3 3 0 Human growth factor-like EGF AAA_16 PF13191.1 EPE31815.1 - 0.04 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_2 PF12679.2 EPE31815.1 - 0.049 12.4 22.8 0.018 13.8 5.8 2.5 2 1 1 3 3 3 0 ABC-2 family transporter protein AAA_22 PF13401.1 EPE31815.1 - 0.052 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EPE31815.1 - 0.075 12.0 0.0 3.6 6.5 0.0 2.2 1 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EPE31815.1 - 0.083 12.4 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain EGF_2 PF07974.8 EPE31815.1 - 0.19 11.9 27.0 0.1 12.7 6.7 4.2 3 0 0 3 3 3 0 EGF-like domain Aminotran_1_2 PF00155.16 EPE31816.1 - 3e-40 138.3 0.0 3.8e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPE31816.1 - 3.7e-06 25.9 0.0 5.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EPE31816.1 - 7.9e-06 24.3 0.0 1.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EPE31816.1 - 0.00018 20.7 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.2 EPE31816.1 - 0.00021 19.9 0.0 0.00031 19.4 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EPE31816.1 - 0.037 13.0 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 EPE31816.1 - 0.056 12.0 0.2 0.4 9.2 0.1 2.1 1 1 1 2 2 2 0 Allinase DnaJ-X PF14308.1 EPE31817.1 - 8.1e-72 240.7 3.9 8.1e-72 240.7 2.7 3.1 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EPE31817.1 - 2.5e-24 84.7 0.4 8.2e-24 83.1 0.3 2.0 1 0 0 1 1 1 1 DnaJ domain RmlD_sub_bind PF04321.12 EPE31818.1 - 6.1e-15 54.8 0.0 1.2e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EPE31818.1 - 5.8e-14 52.0 0.0 1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPE31818.1 - 8.6e-06 24.8 0.0 6.1e-05 22.0 0.0 2.2 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPE31818.1 - 2.9e-05 24.0 0.0 5.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE31818.1 - 0.0092 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EPE31818.1 - 0.012 14.3 0.0 0.025 13.2 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TPT PF03151.11 EPE31819.1 - 9.7e-13 48.0 12.0 9.7e-13 48.0 8.3 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EPE31819.1 - 1.4e-06 28.3 27.8 1e-05 25.5 8.1 3.3 2 2 1 3 3 3 2 EamA-like transporter family 7TMR-DISM_7TM PF07695.6 EPE31819.1 - 0.53 9.9 25.4 0.37 10.4 5.7 2.4 2 1 1 3 3 3 0 7TM diverse intracellular signalling TPT PF03151.11 EPE31820.1 - 6.4e-17 61.6 4.0 6.4e-17 61.6 2.8 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EPE31820.1 - 1.5e-05 25.0 5.4 1.5e-05 25.0 3.7 3.1 2 2 2 4 4 4 3 EamA-like transporter family DUF3442 PF11924.3 EPE31820.1 - 0.088 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3442) Nuc_sug_transp PF04142.10 EPE31820.1 - 0.24 10.4 7.5 0.99 8.4 5.3 2.0 1 1 0 1 1 1 0 Nucleotide-sugar transporter SQS_PSY PF00494.14 EPE31821.1 - 4.8e-36 124.4 0.0 9.5e-36 123.4 0.0 1.5 2 0 0 2 2 2 1 Squalene/phytoene synthase AMP-binding PF00501.23 EPE31822.1 - 2.3e-63 214.0 0.0 3e-62 210.3 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE31822.1 - 9.1e-11 42.5 0.0 1.6e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FHA PF00498.21 EPE31823.1 - 8.2e-08 32.2 0.1 1.7e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain Cyt-b5 PF00173.23 EPE31824.1 - 1.4e-13 50.4 0.0 2.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HET PF06985.6 EPE31825.1 - 0.017 15.3 0.3 0.061 13.4 0.1 2.2 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) Tnp_P_element PF12017.3 EPE31826.1 - 1 8.5 3.5 6.5 5.9 0.1 2.1 2 0 0 2 2 2 0 Transposase protein IF4E PF01652.13 EPE31827.1 - 1.6e-59 200.1 0.1 1.9e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.7 EPE31828.1 - 5.3e-26 90.0 1.3 9.1e-26 89.2 0.9 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family WSC PF01822.14 EPE31830.1 - 1e-49 166.3 47.2 1.1e-21 76.5 10.4 3.6 4 0 0 4 4 4 3 WSC domain Translin PF01997.11 EPE31831.1 - 3e-61 206.5 0.0 3.5e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Translin family ECM11 PF15463.1 EPE31831.1 - 0.069 13.4 0.6 0.069 13.4 0.4 1.9 2 1 0 2 2 2 0 Extracellular mutant protein 11 NPV_P10 PF05531.7 EPE31831.1 - 0.19 11.9 3.8 12 6.2 0.1 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mannosyl_trans PF05007.8 EPE31832.1 - 3.5e-82 275.9 13.4 5.4e-82 275.3 9.3 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) DUF2029 PF09594.5 EPE31832.1 - 6.2e-11 42.2 7.7 6.2e-11 42.2 5.3 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2029) F-box-like PF12937.2 EPE31833.1 - 0.0012 18.5 0.0 0.0045 16.6 0.0 2.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EPE31833.1 - 0.86 9.3 3.4 1.8 8.2 0.2 2.6 2 0 0 2 2 2 0 F-box domain Peptidase_S10 PF00450.17 EPE31834.1 - 3.9e-82 276.6 0.1 6.6e-82 275.8 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Thaumatin PF00314.12 EPE31835.1 - 4.3e-21 75.3 2.0 5.6e-21 74.9 1.4 1.2 1 0 0 1 1 1 1 Thaumatin family Axin_b-cat_bind PF08833.5 EPE31835.1 - 0.022 14.4 0.2 0.054 13.2 0.2 1.7 1 0 0 1 1 1 0 Axin beta-catenin binding domain PLAC8 PF04749.12 EPE31836.1 - 9.1 6.8 7.5 0.53 10.8 0.4 2.4 2 1 1 3 3 3 0 PLAC8 family HET PF06985.6 EPE31837.1 - 3e-21 76.0 1.1 3.8e-21 75.7 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4222 PF13973.1 EPE31837.1 - 1.7 8.0 4.4 0.3 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4222) GATase_5 PF13507.1 EPE31838.1 - 0.033 13.1 0.0 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Med8 PF10232.4 EPE31841.1 - 3.8e-30 105.1 1.0 4.9e-30 104.7 0.7 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Rotamase PF00639.16 EPE31841.1 - 0.07 13.8 0.0 0.26 12.0 0.0 2.0 1 1 0 1 1 1 0 PPIC-type PPIASE domain Tim54 PF11711.3 EPE31841.1 - 0.24 9.9 5.5 0.039 12.5 0.9 1.7 1 1 1 2 2 2 0 Inner membrane protein import complex subunit Tim54 DNA_pol_phi PF04931.8 EPE31841.1 - 8.5 4.0 7.0 12 3.5 4.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi zf-RING_2 PF13639.1 EPE31843.1 - 7.1e-11 41.7 8.1 7.1e-11 41.7 5.6 1.9 2 0 0 2 2 2 1 Ring finger domain SAP PF02037.22 EPE31843.1 - 5.5e-10 38.5 0.3 1.4e-09 37.2 0.2 1.7 1 0 0 1 1 1 1 SAP domain zf-rbx1 PF12678.2 EPE31843.1 - 5.5e-06 26.4 6.6 1.3e-05 25.2 4.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPE31843.1 - 6.9e-05 22.6 6.0 6.9e-05 22.6 4.2 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EPE31843.1 - 0.0015 18.1 10.8 0.0038 16.8 7.5 1.7 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.1 EPE31843.1 - 0.012 15.6 9.1 0.012 15.6 6.3 1.9 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EPE31843.1 - 0.012 15.5 11.3 0.012 15.5 7.8 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain Baculo_RING PF05883.6 EPE31843.1 - 0.013 15.2 3.3 0.036 13.9 2.3 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 EPE31843.1 - 0.047 13.5 8.3 0.31 10.9 5.9 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3371 PF11851.3 EPE31843.1 - 0.09 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) zf-RING_4 PF14570.1 EPE31843.1 - 0.11 12.0 10.2 0.28 10.8 7.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.7 EPE31843.1 - 0.16 12.1 2.7 3.6 7.7 0.0 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_4 PF13717.1 EPE31843.1 - 0.23 11.1 4.1 0.19 11.4 0.8 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EPE31843.1 - 0.53 9.9 5.5 0.14 11.7 0.6 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 EPE31843.1 - 0.81 9.4 11.3 0.25 11.1 4.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.2 EPE31843.1 - 0.95 9.5 10.6 2.2 8.3 7.4 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.20 EPE31843.1 - 3.3 7.4 15.3 0.061 13.0 5.5 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE31843.1 - 4.7 6.9 12.8 0.097 12.3 3.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.6 EPE31843.1 - 7.2 6.3 9.0 6 6.6 2.5 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain DUF1966 PF09260.6 EPE31844.1 - 0.13 12.3 0.4 0.18 11.8 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1966) FAD_binding_4 PF01565.18 EPE31845.1 - 1.4e-25 89.3 0.7 2.4e-25 88.6 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.13 EPE31846.1 - 1.9e-08 34.0 14.2 3.7e-08 33.1 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE31846.1 - 0.0008 18.3 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Oxidored_FMN PF00724.15 EPE31847.1 - 7.1e-63 212.6 0.0 8.8e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EPE31847.1 - 0.026 13.3 0.0 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) HET PF06985.6 EPE31848.1 - 6.8e-24 84.6 0.3 1.5e-23 83.5 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) 4HBT_3 PF13622.1 EPE31849.1 - 1.3e-48 166.0 0.0 1.4e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EPE31849.1 - 0.0077 16.3 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 1 Thioesterase superfamily ArfGap PF01412.13 EPE31850.1 - 1.2e-33 115.3 2.1 2.2e-33 114.4 0.0 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EPE31850.1 - 1.2e-11 44.7 0.0 5.7e-11 42.5 0.0 2.2 1 0 0 1 1 1 1 PH domain EMP24_GP25L PF01105.19 EPE31850.1 - 0.62 9.7 4.7 2.4 7.8 2.1 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD C2 PF00168.25 EPE31851.1 - 4.3e-11 42.5 0.0 7.8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF2183 PF09949.4 EPE31851.1 - 0.049 13.5 0.2 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) Proteasome PF00227.21 EPE31852.1 - 7.6e-28 97.0 0.0 9.3e-28 96.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 EPE31853.1 - 4.1e-33 113.2 1.3 7.1e-33 112.5 0.9 1.3 1 0 0 1 1 1 1 HCNGP-like protein Pkinase PF00069.20 EPE31854.1 - 6.6e-77 258.1 0.0 1.2e-76 257.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE31854.1 - 7.1e-39 133.4 0.0 1.1e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EPE31854.1 - 2e-16 59.8 0.1 4.6e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EPE31854.1 - 8.3e-11 41.3 0.0 2.1e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPE31854.1 - 7e-06 25.9 0.0 2.3e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPE31854.1 - 0.016 14.0 0.1 0.036 12.8 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EPE31854.1 - 0.016 14.2 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPE31854.1 - 0.064 12.5 0.1 0.14 11.4 0.1 1.5 1 0 0 1 1 1 0 RIO1 family NUDE_C PF04880.8 EPE31854.1 - 0.18 12.1 2.2 0.45 10.8 1.5 1.6 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region adh_short PF00106.20 EPE31856.1 - 2.4e-06 27.5 0.2 6.5e-06 26.1 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EPE31856.1 - 0.00027 20.8 2.3 0.061 13.3 0.0 2.5 1 1 1 2 2 2 2 TrkA-N domain KR PF08659.5 EPE31856.1 - 0.00084 19.0 0.1 0.003 17.2 0.0 2.0 2 1 0 2 2 2 1 KR domain Fungal_trans_2 PF11951.3 EPE31857.1 - 6.2e-58 196.2 5.9 7.7e-58 195.9 4.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE31857.1 - 4.2e-09 36.1 4.5 7.9e-09 35.2 3.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3328 PF11807.3 EPE31858.1 - 0.0011 18.7 2.4 0.0028 17.3 1.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) TauD PF02668.11 EPE31859.1 - 1.2e-46 159.4 0.0 1.8e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EPE31859.1 - 0.11 13.0 0.0 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EPE31860.1 - 1.4e-26 93.0 69.6 1.1e-23 83.6 32.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.26 EPE31861.1 - 2.9e-06 27.2 0.0 5.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EPE31862.1 - 0.021 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Tim54 PF11711.3 EPE31862.1 - 1.7 7.1 9.0 0.032 12.8 0.6 1.9 1 1 1 2 2 2 0 Inner membrane protein import complex subunit Tim54 FGGY_C PF02782.11 EPE31863.1 - 2.3e-27 95.8 0.0 8e-27 94.1 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EPE31863.1 - 5.9e-20 71.6 0.0 4.3e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.16 EPE31864.1 - 1.5e-58 198.1 0.1 1.8e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family UreE_C PF05194.7 EPE31864.1 - 1.9 8.6 24.4 1.1 9.3 0.3 3.6 3 0 0 3 3 3 0 UreE urease accessory protein, C-terminal domain PAP2 PF01569.16 EPE31864.1 - 2.1 8.0 6.7 3 7.5 0.8 2.6 1 1 1 2 2 2 0 PAP2 superfamily SIR2 PF02146.12 EPE31865.1 - 5.9e-30 104.2 0.0 1.4e-29 103.0 0.0 1.7 2 0 0 2 2 2 1 Sir2 family Methyltransf_2 PF00891.13 EPE31865.1 - 8.2e-24 84.1 0.0 1.8e-23 83.0 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase Dimerisation PF08100.6 EPE31865.1 - 0.00062 19.5 0.3 0.0023 17.6 0.1 2.2 2 0 0 2 2 2 1 Dimerisation domain DUF1654 PF07867.6 EPE31866.1 - 0.044 13.1 1.8 0.14 11.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) RAMP4 PF06624.7 EPE31866.1 - 0.094 12.2 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 DUF4407 PF14362.1 EPE31866.1 - 1 8.2 3.5 0.86 8.5 1.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_C50 PF03568.12 EPE31867.1 - 7.5e-119 396.8 0.0 2.7e-118 394.9 0.0 2.1 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 EPE31867.1 - 0.014 15.3 14.3 0.67 9.9 0.2 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPE31867.1 - 0.019 14.7 0.5 0.36 10.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPE31867.1 - 0.21 12.3 4.6 27 5.7 0.7 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPE31868.1 - 8.8e-50 166.2 26.4 1.4e-19 69.4 4.3 6.7 3 2 1 6 6 6 5 TPR repeat TPR_1 PF00515.23 EPE31868.1 - 4.8e-39 130.3 24.5 2.9e-06 26.6 0.1 9.4 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 EPE31868.1 - 9.4e-37 121.9 23.4 2.1e-07 30.3 0.1 9.3 7 1 2 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EPE31868.1 - 2.8e-29 101.1 22.6 8.3e-08 32.7 0.8 6.9 5 2 2 7 7 7 5 Tetratricopeptide repeat DnaJ PF00226.26 EPE31868.1 - 2.9e-27 94.1 4.1 2.9e-27 94.1 2.8 3.0 3 0 0 3 3 3 1 DnaJ domain TPR_14 PF13428.1 EPE31868.1 - 1.8e-21 74.6 20.9 3.1e-05 24.2 0.2 9.0 4 3 5 9 9 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EPE31868.1 - 6.5e-21 74.4 26.4 2.5e-08 34.1 0.1 6.8 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EPE31868.1 - 1.5e-18 65.1 19.3 0.0043 16.7 0.0 9.4 6 2 4 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 EPE31868.1 - 4.5e-18 64.9 19.4 9.6e-06 25.4 0.0 6.7 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 EPE31868.1 - 1.6e-15 56.7 14.1 0.00026 20.7 0.0 6.4 4 1 2 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EPE31868.1 - 3.5e-15 55.8 6.8 4.6e-08 33.0 0.1 4.6 2 1 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EPE31868.1 - 1.7e-14 52.7 27.5 0.00091 19.2 0.3 8.3 10 0 0 10 10 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 EPE31868.1 - 2.2e-12 45.7 18.4 0.027 14.2 0.0 8.0 8 1 0 8 8 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 EPE31868.1 - 5.2e-10 39.1 20.4 0.0031 17.8 0.1 8.8 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 EPE31868.1 - 2.7e-06 26.6 10.1 0.06 12.3 0.1 4.5 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.9 EPE31868.1 - 4.1e-06 26.6 4.2 0.0024 18.1 0.2 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EPE31868.1 - 0.00011 22.2 13.7 0.22 11.6 0.3 5.1 3 3 2 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.12 EPE31868.1 - 0.00061 20.1 4.0 14 5.9 0.1 4.5 3 2 1 4 4 4 0 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.1 EPE31868.1 - 0.0013 19.0 6.9 2.4 8.3 0.0 4.6 2 2 2 4 4 4 1 Alkyl sulfatase dimerisation Coatomer_E PF04733.9 EPE31868.1 - 0.011 14.9 2.4 1.4 8.0 0.0 3.0 2 1 1 3 3 3 0 Coatomer epsilon subunit NARP1 PF12569.3 EPE31868.1 - 0.023 13.4 10.0 0.21 10.2 0.3 3.5 2 1 0 3 3 3 0 NMDA receptor-regulated protein 1 NatB_MDM20 PF09797.4 EPE31868.1 - 0.031 12.9 0.0 0.065 11.9 0.0 1.5 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit TOM20_plant PF06552.7 EPE31868.1 - 0.043 13.4 3.2 0.48 9.9 0.1 3.2 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_10 PF13374.1 EPE31868.1 - 0.045 13.6 15.5 0.65 10.0 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EPE31868.1 - 0.05 13.4 8.4 7.8 6.4 0.6 4.4 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 EPE31868.1 - 0.15 11.8 3.2 54 3.5 0.0 4.9 4 2 0 5 5 5 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 EPE31868.1 - 0.63 9.9 13.1 3.1 7.7 0.1 4.9 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 EPE31868.1 - 1.1 9.1 18.9 0.88 9.5 0.5 5.1 3 3 1 5 5 5 0 Tetratricopeptide repeat DUF3366 PF11846.3 EPE31868.1 - 2.5 7.9 8.4 19 5.0 0.0 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF3366) BTB PF00651.26 EPE31869.1 - 4.1e-05 23.5 0.0 8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain RNA_pol_3_Rpc31 PF11705.3 EPE31869.1 - 0.18 11.7 13.2 0.25 11.2 9.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 EPE31869.1 - 1.7 6.6 11.6 2.2 6.2 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 EPE31869.1 - 5.8 5.0 10.1 1 7.5 4.5 1.5 2 0 0 2 2 2 0 VID27 cytoplasmic protein Nop14 PF04147.7 EPE31869.1 - 8.7 4.1 16.8 11 3.7 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family NTF2 PF02136.15 EPE31873.1 - 3.4e-23 82.2 0.6 5e-23 81.7 0.4 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EPE31873.1 - 1.1e-07 31.3 0.0 2.7e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE31873.1 - 2.4e-06 27.4 0.0 6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE31873.1 - 0.00068 19.4 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 EPE31873.1 - 0.94 7.6 21.6 1.3 7.1 15.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPR_11 PF13414.1 EPE31874.1 - 0.00021 20.8 3.5 0.061 12.9 0.0 4.0 5 1 0 5 5 5 2 TPR repeat TPR_17 PF13431.1 EPE31874.1 - 0.02 15.0 0.8 8.4 6.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPE31874.1 - 0.029 15.0 1.6 2.6 8.8 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPE31874.1 - 0.085 13.5 3.8 0.53 11.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Nro1 PF12753.2 EPE31874.1 - 0.11 11.3 0.0 0.11 11.3 0.0 2.5 3 0 0 3 3 3 0 Nuclear pore complex subunit Nro1 Nckap1 PF09735.4 EPE31874.1 - 0.2 9.1 0.3 0.41 8.0 0.0 1.6 1 1 1 2 2 2 0 Membrane-associated apoptosis protein DUF2408 PF10303.4 EPE31875.1 - 0.046 13.8 0.7 0.058 13.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) APH PF01636.18 EPE31876.1 - 1.6e-09 37.8 0.0 2.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE31876.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SSrecog PF03531.9 EPE31877.1 - 7.2e-73 244.5 0.9 7.8e-72 241.2 0.6 2.3 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EPE31877.1 - 1.8e-26 91.9 0.2 9.8e-26 89.5 0.1 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC45 PF02724.9 EPE31877.1 - 0.0088 14.1 7.0 0.014 13.4 4.8 1.2 1 0 0 1 1 1 1 CDC45-like protein NAD_binding_10 PF13460.1 EPE31878.1 - 2.9e-08 33.9 0.0 3.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EPE31878.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EPE31878.1 - 0.026 13.4 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EPE31878.1 - 0.044 12.7 0.0 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein SNF2_N PF00176.18 EPE31879.1 - 1.7e-44 151.8 0.2 1.6e-43 148.5 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE31879.1 - 4.1e-14 52.1 0.0 1e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE31879.1 - 2.7e-05 24.0 0.0 0.00013 21.8 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GSH_synth_ATP PF03917.12 EPE31880.1 - 5.7e-112 373.9 0.0 6.9e-112 373.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EPE31880.1 - 3.6e-34 116.9 0.0 1.1e-33 115.4 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic glutathione synthase SSB PF00436.20 EPE31881.1 - 6e-19 67.8 0.0 7.4e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family EFG_C PF00679.19 EPE31881.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.5 1 1 0 1 1 1 0 Elongation factor G C-terminus tRNA_anti-codon PF01336.20 EPE31881.1 - 0.036 13.9 0.1 0.047 13.5 0.0 1.4 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain DUF4203 PF13886.1 EPE31882.1 - 2.5e-36 125.1 26.9 3.3e-36 124.7 18.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2681 PF10883.3 EPE31882.1 - 5.6 7.2 8.9 1.9 8.7 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2681) HATPase_c PF02518.21 EPE31883.1 - 1.2e-22 79.7 0.1 2.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE31883.1 - 1.2e-21 76.8 0.1 2.5e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EPE31883.1 - 9.6e-14 51.1 0.1 2.2e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 EPE31883.1 - 0.087 12.5 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 GHKL domain Cation_efflux PF01545.16 EPE31884.1 - 1.5e-31 109.5 0.5 2.1e-31 109.0 0.4 1.1 1 0 0 1 1 1 1 Cation efflux family Glyco_transf_90 PF05686.7 EPE31885.1 - 4.8e-21 74.9 0.1 8.2e-21 74.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 DDHD PF02862.12 EPE31886.1 - 3.5 7.3 9.8 7.3 6.3 6.8 1.5 1 0 0 1 1 1 0 DDHD domain NDUFA12 PF05071.11 EPE31887.1 - 2.2e-11 44.1 0.2 2.2e-11 44.1 0.1 1.7 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Erf4 PF10256.4 EPE31888.1 - 2.9e-27 94.8 0.0 4.7e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ECH PF00378.15 EPE31889.1 - 2e-21 76.2 0.0 2.6e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EPE31889.1 - 0.0009 19.0 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 Glycos_transf_1 PF00534.15 EPE31890.1 - 8.2e-31 106.7 0.1 6.7e-30 103.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Pyr_redox_3 PF13738.1 EPE31890.1 - 5.3e-23 82.1 0.0 8.7e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.1 EPE31890.1 - 2.8e-09 37.3 0.0 1.1e-08 35.4 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EPE31890.1 - 2.5e-07 30.5 0.0 6.6e-06 25.9 0.0 2.6 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EPE31890.1 - 8.6e-06 25.9 0.1 7.4e-05 22.9 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EPE31890.1 - 3.3e-05 24.0 0.0 7.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pyr_redox_2 PF07992.9 EPE31890.1 - 3.4e-05 23.8 0.0 9e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPE31890.1 - 0.011 14.7 0.0 0.03 13.2 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPE31890.1 - 0.022 14.5 0.1 2.5 7.8 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding LRR_4 PF12799.2 EPE31891.1 - 5.9e-25 86.4 42.9 4.9e-07 29.2 0.1 8.5 7 1 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE31891.1 - 8.5e-15 54.2 41.3 9.1e-06 25.3 0.3 7.0 5 2 3 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 EPE31891.1 - 6.6e-06 25.4 39.1 0.51 10.5 0.1 12.8 12 1 1 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.1 EPE31891.1 - 0.089 12.9 29.2 3.1 8.1 0.1 8.9 6 3 2 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 EPE31891.1 - 0.81 10.1 37.2 4.9 7.8 0.1 10.8 10 1 0 10 10 10 0 Leucine rich repeat LRR_9 PF14580.1 EPE31891.1 - 0.91 9.0 19.2 0.25 10.9 0.1 4.0 3 1 2 5 5 5 0 Leucine-rich repeat Cupin_6 PF12852.2 EPE31892.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Cupin SET PF00856.23 EPE31893.1 - 4.8e-18 65.9 1.1 4.8e-18 65.9 0.7 2.6 3 2 0 3 3 3 1 SET domain Mito_carr PF00153.22 EPE31894.1 - 1.4e-74 245.9 2.3 7.9e-25 86.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Herpes_UL37_2 PF07413.6 EPE31894.1 - 0.054 12.2 0.5 0.077 11.7 0.3 1.2 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 Gyro_capsid PF04162.7 EPE31896.1 - 0.033 12.4 0.0 0.035 12.3 0.0 1.0 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Zn_clus PF00172.13 EPE31897.1 - 0.21 11.5 12.4 0.58 10.1 8.6 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP21_like_P PF12230.3 EPE31898.1 - 3.5e-61 206.6 19.0 8e-61 205.4 13.2 1.6 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EPE31898.1 - 1.5e-36 123.8 1.2 2.4e-18 65.4 0.1 2.6 2 0 0 2 2 2 2 Surp module Sec2p PF06428.6 EPE31899.1 - 2.3e-23 81.9 15.4 2.3e-23 81.9 10.7 3.0 3 1 0 3 3 3 1 GDP/GTP exchange factor Sec2p DUF4404 PF14357.1 EPE31899.1 - 0.039 14.3 1.4 0.039 14.3 1.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) DUF3584 PF12128.3 EPE31899.1 - 0.18 9.1 20.5 0.26 8.5 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 EPE31899.1 - 3.7 5.2 16.3 20 2.8 11.4 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L21e PF01157.13 EPE31901.1 - 2e-23 82.0 4.6 2.8e-23 81.6 1.9 1.9 1 1 1 2 2 2 1 Ribosomal protein L21e Ribosomal_S4 PF00163.14 EPE31902.1 - 5.5e-27 93.9 2.2 4.9e-13 49.2 0.1 2.5 1 1 1 2 2 2 2 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EPE31902.1 - 3e-12 45.7 1.3 3e-12 45.7 0.9 2.1 2 0 0 2 2 2 1 S4 domain Slu7 PF11708.3 EPE31903.1 - 1.9e-79 266.7 18.3 3.9e-79 265.7 12.7 1.5 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EPE31903.1 - 0.022 14.3 0.8 0.041 13.5 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle DNA_pol_B PF00136.16 EPE31904.1 - 7.9e-96 321.6 0.0 1.3e-95 320.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EPE31904.1 - 2.7e-22 79.0 0.1 2.9e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EPE31904.1 - 1e-18 67.0 8.3 1.1e-18 66.9 3.5 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta NAD_binding_10 PF13460.1 EPE31905.1 - 0.0029 17.6 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding HsbA PF12296.3 EPE31906.1 - 9.2e-14 51.3 2.8 1.5e-13 50.6 1.9 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A MFS_1 PF07690.11 EPE31907.1 - 5.4e-30 104.2 42.4 5.4e-30 104.2 29.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily FSH1 PF03959.8 EPE31908.1 - 3.2e-24 85.5 0.1 2.6e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EPE31908.1 - 0.035 13.6 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE31908.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.13 EPE31909.1 - 0.00038 20.3 8.4 0.00038 20.3 5.8 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 EPE31910.1 - 2.2e-77 259.9 0.0 4.9e-77 258.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EPE31910.1 - 1.8e-59 200.4 0.0 4.5e-59 199.1 0.0 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EPE31910.1 - 5e-57 193.6 0.6 7.6e-57 193.0 0.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EPE31910.1 - 3.5e-46 157.1 0.1 9.3e-45 152.5 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPE31910.1 - 1.4e-34 118.4 0.2 5.3e-34 116.6 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EPE31910.1 - 1.6e-33 116.1 0.0 2.9e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EPE31910.1 - 4e-19 68.4 0.0 1.6e-18 66.4 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE31910.1 - 3.3e-08 34.4 0.0 1.5e-07 32.3 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EPE31910.1 - 7.8e-06 26.0 0.0 2.6e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EPE31910.1 - 0.0001 21.4 0.0 0.00034 19.7 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_N PF08240.7 EPE31910.1 - 0.00023 20.9 0.1 0.00059 19.5 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_12 PF08242.7 EPE31910.1 - 0.0024 18.3 0.0 0.0086 16.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ELFV_dehydrog PF00208.16 EPE31910.1 - 0.015 14.9 2.7 1.5 8.3 0.0 3.3 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Methyltransf_23 PF13489.1 EPE31910.1 - 0.016 14.9 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EPE31910.1 - 0.028 14.0 0.0 0.084 12.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EPE31910.1 - 0.055 14.0 0.0 0.33 11.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain HET PF06985.6 EPE31911.1 - 3.3e-33 114.8 0.5 6e-33 113.9 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2404 PF10296.4 EPE31912.1 - 1.2e-30 105.4 0.0 2.4e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Spore_YhaL PF14147.1 EPE31912.1 - 0.017 14.5 0.3 0.058 12.8 0.2 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL PH PF00169.24 EPE31912.1 - 0.041 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 PH domain ANTH PF07651.11 EPE31913.1 - 4.5e-81 271.6 2.5 9.5e-81 270.5 0.0 2.9 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.12 EPE31913.1 - 1.7e-62 209.8 6.2 1.7e-62 209.8 4.3 5.4 4 2 2 6 6 6 2 I/LWEQ domain ENTH PF01417.15 EPE31913.1 - 0.0012 18.7 0.0 0.0066 16.2 0.0 2.4 1 1 0 1 1 1 1 ENTH domain Med15 PF09606.5 EPE31913.1 - 4.5 5.3 50.9 0.047 11.8 28.2 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MAT_Alpha1 PF04769.7 EPE31914.1 - 2.7e-38 131.3 0.1 4.3e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 MORN_2 PF07661.8 EPE31915.1 - 0.065 13.2 0.1 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 MORN repeat variant HMG_box PF00505.14 EPE31916.1 - 5e-17 61.9 0.2 8.2e-17 61.2 0.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box DUF2462 PF09495.5 EPE31916.1 - 0.042 14.5 0.4 0.079 13.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) Exo_endo_phos_2 PF14529.1 EPE31917.1 - 3.1e-16 59.0 0.0 5.7e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EPE31917.1 - 1.2e-15 58.1 0.0 2.5e-15 57.0 0.0 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EPE31917.1 - 0.00017 21.4 1.4 0.00043 20.1 0.9 1.7 1 0 0 1 1 1 1 GRF zinc finger CDC27 PF09507.5 EPE31917.1 - 0.036 13.3 1.5 0.055 12.6 1.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 COX6A PF02046.10 EPE31918.1 - 3.3e-45 152.7 2.1 3.8e-45 152.5 1.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa IspA PF04279.10 EPE31918.1 - 0.12 12.3 0.5 0.16 11.9 0.4 1.1 1 0 0 1 1 1 0 Intracellular septation protein A Apc5 PF12862.2 EPE31919.1 - 2.6e-34 116.9 3.4 2.6e-34 116.9 2.3 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EPE31919.1 - 0.18 11.7 13.6 3.1 7.7 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat CIA30 PF08547.7 EPE31922.1 - 1.5e-41 141.8 0.0 1.9e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RRM_1 PF00076.17 EPE31923.1 - 3e-29 100.4 0.3 2.6e-15 55.8 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE31923.1 - 1.5e-17 63.3 0.1 1.5e-10 40.9 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE31923.1 - 1.1e-11 44.3 0.6 7.2e-06 25.7 0.1 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0139 PF03669.8 EPE31925.1 - 3.9e-05 23.1 0.2 0.0001 21.7 0.1 1.7 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0139) Med12 PF09497.5 EPE31926.1 - 5.6e-27 93.5 0.3 1.8e-26 91.8 0.2 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 EPE31926.1 - 0.017 13.6 0.1 0.037 12.5 0.0 1.5 2 0 0 2 2 2 0 Eukaryotic Mediator 12 subunit domain RhoGAP PF00620.22 EPE31927.1 - 3.7e-49 166.2 0.0 2.1e-48 163.8 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EPE31927.1 - 2.6e-14 53.1 0.5 7.3e-14 51.7 0.4 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RapA_C PF12137.3 EPE31927.1 - 0.014 14.2 0.0 0.029 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Scaffolding_pro PF11418.3 EPE31927.1 - 0.17 12.2 2.0 3.8 7.9 0.0 2.9 2 1 0 2 2 2 0 Phi29 scaffolding protein OmpH PF03938.9 EPE31927.1 - 0.61 10.0 6.5 1.5 8.7 4.5 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Rootletin PF15035.1 EPE31927.1 - 2.4 8.1 7.8 0.14 12.1 0.4 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Zn_clus PF00172.13 EPE31928.1 - 5.9e-10 38.8 14.0 9.2e-10 38.2 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE31928.1 - 1.8e-07 30.1 0.4 2.4e-07 29.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SAICAR_synt PF01259.13 EPE31929.1 - 4.9e-82 274.7 0.0 6.2e-82 274.4 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase SSF PF00474.12 EPE31930.1 - 0.04 12.5 34.2 0.35 9.4 23.7 2.1 1 1 0 1 1 1 0 Sodium:solute symporter family NDUF_B12 PF08122.7 EPE31930.1 - 1.2 8.8 5.7 0.25 11.1 0.6 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family SUI1 PF01253.17 EPE31931.1 - 2.2e-29 101.0 5.8 2.9e-29 100.6 4.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 EPE31931.1 - 0.13 12.3 0.4 0.38 10.8 0.1 1.7 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) EOS1 PF12326.3 EPE31932.1 - 5e-28 97.6 13.7 2.8e-25 88.7 4.3 2.0 1 1 1 2 2 2 2 N-glycosylation protein Tim44 PF04280.10 EPE31933.1 - 1.1e-06 28.6 0.1 1.7e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.6 EPE31933.1 - 2.4e-05 23.2 0.0 0.00057 18.7 0.0 2.0 2 0 0 2 2 2 2 MBA1-like protein Yae1_N PF09811.4 EPE31934.1 - 3e-14 52.2 1.4 5.9e-14 51.3 1.0 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Glyoxal_oxid_N PF07250.6 EPE31936.1 - 4.4e-41 140.5 0.0 1e-40 139.3 0.0 1.6 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EPE31936.1 - 1.6e-23 82.6 0.4 3.9e-23 81.3 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.14 EPE31936.1 - 7.5e-06 25.8 39.4 7.6e-06 25.8 16.9 2.5 2 0 0 2 2 2 2 Chitin recognition protein Annexin PF00191.15 EPE31937.1 - 3.7e-15 55.5 0.4 0.00046 20.0 0.0 4.4 4 0 0 4 4 4 4 Annexin DUF2235 PF09994.4 EPE31938.1 - 5.6e-75 252.2 0.0 7.6e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Endonuc-FokI_C PF09254.6 EPE31939.1 - 0.055 12.5 1.6 0.056 12.5 0.3 1.5 1 1 1 2 2 2 0 Restriction endonuclease FokI, C terminal CFEM PF05730.6 EPE31940.1 - 5.4e-11 42.1 9.6 8.7e-11 41.4 6.6 1.3 1 0 0 1 1 1 1 CFEM domain adh_short PF00106.20 EPE31941.1 - 2.6e-05 24.2 0.1 0.00064 19.6 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase m04gp34like PF12216.3 EPE31943.1 - 0.12 11.7 0.1 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Immune evasion protein Aldo_ket_red PF00248.16 EPE31945.1 - 4.6e-54 183.1 0.0 5.5e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RCC1 PF00415.13 EPE31946.1 - 1.4e-53 178.9 0.0 1.5e-09 37.9 0.2 7.7 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPE31946.1 - 5e-29 99.2 29.2 7.2e-08 31.8 0.6 6.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Acyl-CoA_dh_1 PF00441.19 EPE31947.1 - 1.1e-29 103.4 2.9 1.5e-29 103.0 2.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPE31947.1 - 2.3e-23 81.4 0.6 4.1e-23 80.6 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EPE31947.1 - 2.4e-19 69.9 0.0 8.2e-19 68.2 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain FAD_binding_4 PF01565.18 EPE31948.1 - 1.4e-17 63.4 0.1 3.2e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain ACPS PF01648.15 EPE31951.1 - 1.7e-05 24.6 0.0 0.00012 21.9 0.0 2.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ribosomal_S16 PF00886.14 EPE31951.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S16 MIP PF00230.15 EPE31952.1 - 1.7e-48 165.1 7.3 2.1e-48 164.7 5.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein PRA1 PF03208.14 EPE31952.1 - 0.15 11.3 0.6 0.38 10.0 0.1 1.8 2 0 0 2 2 2 0 PRA1 family protein Fer4_12 PF13353.1 EPE31953.1 - 0.00019 21.5 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EPE31953.1 - 0.0027 17.7 0.0 0.008 16.2 0.0 1.7 1 1 1 2 2 2 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 EPE31953.1 - 0.0065 16.6 0.0 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Herpes_UL47 PF03362.8 EPE31953.1 - 0.07 11.4 0.2 0.11 10.7 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL47 protein NmrA PF05368.8 EPE31954.1 - 2.4e-34 118.6 0.1 3.2e-34 118.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE31954.1 - 6.7e-17 62.0 0.0 8.6e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE31954.1 - 0.00026 20.5 0.0 0.003 17.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EPE31954.1 - 0.0069 16.3 0.1 0.014 15.3 0.1 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EPE31954.1 - 0.022 15.0 0.1 0.04 14.2 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EPE31954.1 - 0.04 13.8 0.1 0.079 12.8 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase DUF3842 PF12953.2 EPE31954.1 - 0.09 12.9 0.2 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) F420_oxidored PF03807.12 EPE31954.1 - 0.25 11.8 1.4 0.48 10.8 0.1 2.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent EI24 PF07264.6 EPE31955.1 - 7.9e-07 28.7 8.6 2.1e-06 27.3 6.0 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) TRIC PF05197.8 EPE31957.1 - 0.18 11.2 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 TRIC channel adh_short PF00106.20 EPE31958.1 - 2.8e-23 82.6 0.0 4.5e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE31958.1 - 7.8e-13 48.7 0.0 9.5e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPE31958.1 - 1.2e-05 25.3 0.7 2.6e-05 24.2 0.1 1.8 2 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EPE31958.1 - 0.00014 21.6 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 EPE31958.1 - 0.0033 16.6 0.0 0.0067 15.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EPE31958.1 - 0.0034 16.9 0.3 0.0061 16.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.8 EPE31958.1 - 0.013 14.8 0.1 0.062 12.5 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Epimerase PF01370.16 EPE31958.1 - 0.016 14.6 0.1 0.032 13.6 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EPE31958.1 - 0.027 14.4 0.1 0.071 13.1 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain MGS PF02142.17 EPE31958.1 - 0.055 13.4 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 MGS-like domain Cu_amine_oxidN2 PF02727.11 EPE31959.1 - 0.15 12.1 0.1 0.52 10.4 0.1 1.8 2 0 0 2 2 2 0 Copper amine oxidase, N2 domain DUF3431 PF11913.3 EPE31960.1 - 5e-25 88.2 0.0 8.5e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4231 PF14015.1 EPE31960.1 - 4.8 7.1 9.1 0.27 11.2 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Glyco_hydro_30 PF02055.11 EPE31962.1 - 4.8e-19 67.9 2.1 1e-12 47.0 0.9 2.7 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EPE31962.1 - 2.9e-17 62.6 3.9 1.7e-16 60.1 0.0 2.1 1 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 DUF3745 PF12560.3 EPE31963.1 - 0.21 11.2 1.3 0.45 10.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3745) ADH_zinc_N PF00107.21 EPE31964.1 - 6.5e-12 45.1 1.2 4.5e-10 39.1 0.8 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE31964.1 - 2.3e-06 27.3 0.0 0.00072 19.2 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EPE31964.1 - 2.3e-05 24.4 2.6 3.8e-05 23.7 1.8 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE31964.1 - 0.00071 19.0 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPE31964.1 - 0.0058 15.5 0.1 0.0088 14.9 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EPE31964.1 - 0.025 14.4 1.3 0.036 13.9 0.9 1.2 1 0 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EPE31964.1 - 0.033 15.0 0.3 0.077 13.8 0.1 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPE31964.1 - 0.034 13.3 0.1 0.068 12.3 0.1 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 EPE31964.1 - 0.081 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Eno-Rase_NADH_b PF12242.3 EPE31964.1 - 0.084 12.6 0.4 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.11 EPE31965.1 - 5.2e-48 163.5 48.5 3.6e-47 160.7 32.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily MtrF PF09472.5 EPE31965.1 - 0.016 14.4 4.7 0.025 13.8 0.0 2.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) CHASE2 PF05226.6 EPE31965.1 - 0.12 11.5 1.1 0.23 10.6 0.7 1.5 1 0 0 1 1 1 0 CHASE2 domain DUF2985 PF11204.3 EPE31966.1 - 4.3e-30 103.2 3.6 9.9e-30 102.1 2.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Ctr PF04145.10 EPE31967.1 - 3.8e-43 147.0 1.1 7.9e-43 145.9 0.7 1.5 1 1 0 1 1 1 1 Ctr copper transporter family DUF443 PF04276.7 EPE31967.1 - 0.0041 16.5 0.5 0.0077 15.6 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF443) DUF3328 PF11807.3 EPE31969.1 - 1.2e-42 146.0 5.7 1.4e-42 145.8 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Dioxygenase_C PF00775.16 EPE31970.1 - 7.8e-07 28.5 0.3 2.1e-06 27.1 0.2 1.8 1 1 0 1 1 1 1 Dioxygenase GXGXG PF01493.14 EPE31970.1 - 0.047 12.6 1.3 0.075 12.0 0.9 1.2 1 0 0 1 1 1 0 GXGXG motif CAP59_mtransfer PF11735.3 EPE31972.1 - 0.0045 16.2 0.0 0.0056 15.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CAP59_mtransfer PF11735.3 EPE31973.1 - 2.3e-56 190.7 0.0 2.7e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 hEGF PF12661.2 EPE31974.1 - 0.075 13.1 2.5 0.15 12.2 1.8 1.5 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.8 EPE31974.1 - 0.41 10.8 8.6 0.79 9.9 6.0 1.5 1 0 0 1 1 1 0 EGF-like domain BTB PF00651.26 EPE31975.1 - 1.9e-07 31.0 0.0 3.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Rep_4 PF05797.6 EPE31975.1 - 0.029 13.0 0.7 0.042 12.5 0.0 1.5 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) TFIIF_alpha PF05793.7 EPE31975.1 - 3.8 5.7 5.4 5.1 5.3 3.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sec66 PF09802.4 EPE31976.1 - 4.7e-23 81.5 0.5 7e-23 81.0 0.3 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Arb2 PF09757.4 EPE31978.1 - 1.6e-24 86.3 0.0 2.4e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Ribosomal_S14 PF00253.16 EPE31979.1 - 4.3e-17 61.2 1.2 6.7e-17 60.6 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e TPR_11 PF13414.1 EPE31981.1 - 2.3e-10 39.9 9.4 6.7e-07 28.8 0.0 4.4 4 1 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EPE31981.1 - 1e-07 31.2 15.5 0.0015 18.3 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE31981.1 - 2.1e-06 28.2 21.8 0.049 14.3 0.1 6.1 4 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPE31981.1 - 5.8e-06 26.1 9.8 0.11 12.4 0.1 4.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPE31981.1 - 8.5e-05 21.9 15.0 0.0079 15.7 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPE31981.1 - 0.0076 15.9 2.1 3.1 7.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE31981.1 - 0.015 15.8 9.7 14 6.6 0.6 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPE31981.1 - 0.089 12.6 6.7 1.7 8.5 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPE31981.1 - 0.55 10.6 11.6 2.9 8.2 0.0 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF1996 PF09362.5 EPE31982.1 - 6.9e-22 78.2 0.0 9.7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.5 EPE31983.1 - 0.0011 18.7 1.8 0.0015 18.2 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) BTB_2 PF02214.17 EPE31984.1 - 1.8e-07 31.2 0.0 4.4e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EPE31984.1 - 3.6e-05 23.7 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Epimerase PF01370.16 EPE31987.1 - 1.3e-11 44.4 0.0 2.1e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE31987.1 - 9.8e-09 34.3 0.0 1.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EPE31987.1 - 2.4e-06 26.9 0.2 3.8e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE31987.1 - 2e-05 24.6 0.6 0.00011 22.3 0.4 2.3 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPE31987.1 - 4.1e-05 22.6 0.0 6.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EPE31987.1 - 0.00067 18.6 0.1 0.0048 15.8 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EPE31987.1 - 0.00073 19.2 0.1 0.0016 18.1 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EPE31987.1 - 0.00089 19.2 0.1 0.0017 18.2 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DUF1996 PF09362.5 EPE31988.1 - 2.9e-83 279.1 4.5 3.8e-83 278.7 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SET PF00856.23 EPE31989.1 - 1.1e-08 35.5 0.0 4.6e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 SET domain zf-MYND PF01753.13 EPE31989.1 - 1.6 8.6 7.4 0.62 9.9 2.6 2.1 2 0 0 2 2 2 0 MYND finger SET PF00856.23 EPE31990.1 - 6.2e-09 36.3 0.0 1.6e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.13 EPE31990.1 - 1.3e-07 31.3 12.5 1.3e-07 31.3 8.7 2.0 2 0 0 2 2 2 1 MYND finger Tcf25 PF04910.9 EPE31990.1 - 0.033 13.1 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 DUF1877 PF08974.5 EPE31990.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) Aldedh PF00171.17 EPE31991.1 - 4.6e-138 460.4 0.0 5.5e-138 460.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPE31991.1 - 0.00024 19.9 0.0 0.00059 18.6 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) COesterase PF00135.23 EPE31992.1 - 4.9e-81 273.0 0.0 1.6e-79 268.0 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE31992.1 - 2.4e-07 30.5 0.0 7.3e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE31992.1 - 0.0043 16.8 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE31992.1 - 0.052 12.7 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Sugar_tr PF00083.19 EPE31993.1 - 5.2e-116 387.8 28.8 5.9e-116 387.6 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE31993.1 - 6.9e-19 67.7 46.4 1.4e-14 53.5 25.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S8 PF00082.17 EPE31995.1 - 6e-25 87.9 0.1 1.3e-24 86.8 0.1 1.5 1 0 0 1 1 1 1 Subtilase family Mito_fiss_reg PF05308.6 EPE31995.1 - 3.7 6.8 10.1 42 3.3 0.0 2.4 2 1 0 2 2 2 0 Mitochondrial fission regulator Amidohydro_2 PF04909.9 EPE31998.1 - 1.8e-26 93.3 0.0 2.3e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase zf-RanBP PF00641.13 EPE31999.1 - 0.00024 20.1 2.1 0.00046 19.2 1.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Imm42 PF15601.1 EPE31999.1 - 0.028 13.8 0.3 0.052 12.9 0.2 1.4 1 0 0 1 1 1 0 Immunity protein 42 zf-Dof PF02701.10 EPE31999.1 - 1.9 8.4 6.1 1.2 9.1 1.9 2.2 2 0 0 2 2 2 0 Dof domain, zinc finger FHA PF00498.21 EPE32000.1 - 2.5e-16 59.5 0.0 6e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain Atg14 PF10186.4 EPE32000.1 - 0.62 8.9 6.7 1.3 7.8 1.2 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 EPE32000.1 - 7 7.0 8.1 0.75 10.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Romo1 PF10247.4 EPE32001.1 - 7.9e-27 93.2 12.3 1e-26 92.8 8.5 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 EPE32001.1 - 0.24 11.4 9.3 1.3 9.1 6.4 1.8 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 EPE32001.1 - 2.7 7.6 5.8 6.2 6.5 2.3 2.0 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain WD40 PF00400.27 EPE32003.1 - 1.8e-14 52.9 3.7 8.6e-06 25.4 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat MFS_1 PF07690.11 EPE32005.1 - 7e-37 126.9 35.0 1.4e-36 125.9 23.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE32005.1 - 1.1e-11 43.9 11.8 1.1e-11 43.9 8.2 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter adh_short PF00106.20 EPE32006.1 - 1.7e-16 60.5 0.0 2.4e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE32006.1 - 1.2e-07 31.5 0.0 1.7e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE32006.1 - 5.2e-07 29.6 0.0 6.8e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPE32006.1 - 0.0015 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ABM PF03992.11 EPE32007.1 - 0.0043 17.0 0.0 0.014 15.4 0.0 1.8 1 1 1 2 2 2 1 Antibiotic biosynthesis monooxygenase zf-RING_2 PF13639.1 EPE32008.1 - 1.7e-11 43.7 6.0 1.7e-11 43.7 4.1 2.7 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EPE32008.1 - 2.3e-05 24.0 6.1 2.3e-05 24.0 4.3 2.8 4 0 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE32008.1 - 3.1e-05 23.5 3.2 3.1e-05 23.5 2.2 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE32008.1 - 3.7e-05 23.6 4.1 3.7e-05 23.6 2.9 3.0 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE32008.1 - 0.00016 21.2 5.0 0.00016 21.2 3.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE32008.1 - 0.0031 17.5 7.6 0.0031 17.5 5.3 2.6 2 1 0 2 2 1 1 RING-H2 zinc finger Tmpp129 PF10272.4 EPE32008.1 - 0.028 13.1 4.1 0.049 12.3 2.8 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-HC5HC2H PF13771.1 EPE32008.1 - 0.047 13.8 0.3 0.047 13.8 0.2 2.4 3 0 0 3 3 3 0 PHD-like zinc-binding domain RINGv PF12906.2 EPE32008.1 - 0.14 12.2 4.6 0.44 10.6 3.2 1.9 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EPE32008.1 - 0.32 10.9 4.7 1.1 9.2 3.2 2.0 1 0 0 1 1 1 0 FANCL C-terminal domain Rubredoxin PF00301.15 EPE32008.1 - 0.46 10.4 4.3 1.5 8.7 0.0 3.2 2 0 0 2 2 2 0 Rubredoxin zf-Apc11 PF12861.2 EPE32008.1 - 0.59 10.0 14.0 0.04 13.7 4.6 2.6 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Abhydrolase_3 PF07859.8 EPE32009.1 - 2.1e-13 50.3 0.0 9.2e-12 44.9 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE32009.1 - 1.1e-12 47.9 0.0 2e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE32009.1 - 8.2e-06 25.8 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE32009.1 - 0.00016 20.9 0.0 0.0053 15.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 EPE32009.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2305 PF10230.4 EPE32009.1 - 0.021 14.2 0.0 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF2235 PF09994.4 EPE32009.1 - 0.028 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_2 PF02230.11 EPE32009.1 - 0.039 13.3 0.0 7.5 5.9 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 EPE32009.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein DUF1947 PF09183.5 EPE32009.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) DUF829 PF05705.9 EPE32012.1 - 1e-37 130.1 0.0 1.2e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF4188 PF13826.1 EPE32013.1 - 3.5e-25 88.3 0.1 5.2e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EPE32013.1 - 0.0014 17.7 1.8 0.0018 17.3 1.3 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase Pyr_redox_2 PF07992.9 EPE32015.1 - 1.3e-14 54.5 0.0 1.8e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE32015.1 - 1.8e-06 27.8 0.8 0.068 12.9 0.0 3.3 4 0 0 4 4 4 2 FAD-NAD(P)-binding GIDA PF01134.17 EPE32015.1 - 2.1e-05 23.5 1.4 0.083 11.7 0.0 2.4 2 1 1 3 3 3 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EPE32015.1 - 4.6e-05 23.5 0.2 0.13 12.2 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE32015.1 - 7.6e-05 21.7 1.2 0.027 13.3 0.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EPE32015.1 - 9.6e-05 21.0 0.1 0.0045 15.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EPE32015.1 - 0.01 14.7 0.4 0.023 13.5 0.0 1.8 3 0 0 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.14 EPE32015.1 - 0.034 13.2 0.0 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 EPE32015.1 - 0.061 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPE32015.1 - 0.084 11.9 0.7 0.17 10.9 0.1 1.8 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.1 EPE32015.1 - 0.1 11.5 0.4 5.5 5.7 0.0 2.4 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Ninjurin PF04923.7 EPE32016.1 - 0.033 13.9 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 Ninjurin DUF1304 PF06993.7 EPE32016.1 - 0.052 13.2 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) RdRP_5 PF07925.6 EPE32016.1 - 0.077 10.3 0.1 0.1 9.9 0.1 1.0 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 F-box PF00646.28 EPE32017.1 - 0.00066 19.2 2.1 0.0015 18.0 1.5 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE32017.1 - 0.041 13.6 3.9 0.1 12.3 2.7 1.7 1 0 0 1 1 1 0 F-box-like Caleosin PF05042.8 EPE32018.1 - 8.9e-62 207.7 0.0 1.2e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein Vsr PF03852.10 EPE32019.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr p450 PF00067.17 EPE32020.1 - 6.2e-60 203.0 0.0 8.3e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EPE32021.1 - 2.7e-08 33.4 0.0 1.7e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE32021.1 - 4.8e-06 26.2 0.1 7.8e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF1699 PF08004.6 EPE32022.1 - 0.066 12.7 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) CorA PF01544.13 EPE32023.1 - 7.3e-06 25.2 1.5 1.1e-05 24.5 0.1 2.0 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein PGAP1 PF07819.8 EPE32024.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EPE32024.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPE32024.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF726 PF05277.7 EPE32024.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) p450 PF00067.17 EPE32026.1 - 2.6e-44 151.5 0.0 3.4e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EPE32027.1 - 7.3e-24 83.8 0.7 1.1e-23 83.2 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE32027.1 - 2.6e-08 33.6 0.0 7.5e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like Peptidase_A4 PF01828.12 EPE32030.1 - 1.4e-22 79.8 0.0 1.8e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF1223 PF06764.6 EPE32031.1 - 6.8e-44 150.1 0.0 8.3e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) DUF3991 PF13154.1 EPE32032.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3991) HSP70 PF00012.15 EPE32033.1 - 1.9e-80 270.5 3.9 2.9e-80 269.9 2.7 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPE32033.1 - 4.5e-09 35.3 0.2 6.9e-09 34.7 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.3 EPE32033.1 - 0.0022 16.9 0.7 2.3 7.0 0.0 2.9 3 0 0 3 3 3 2 Type IV pilus assembly protein PilM; FtsA PF14450.1 EPE32033.1 - 0.38 10.5 5.6 5.8 6.7 0.4 3.1 3 1 0 3 3 3 0 Cell division protein FtsA Glyco_hydro_7 PF00840.15 EPE32034.1 - 2.3e-204 678.7 24.0 2.6e-204 678.5 16.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 NIPSNAP PF07978.8 EPE32037.1 - 9.1e-38 128.3 0.1 9.4e-28 96.1 0.0 2.4 2 0 0 2 2 2 2 NIPSNAP Rogdi_lz PF10259.4 EPE32038.1 - 3.7e-57 193.5 0.0 4.3e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.3 EPE32039.1 - 4.7e-31 107.3 0.6 9.3e-31 106.4 0.5 1.5 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EPE32039.1 - 3.8e-20 71.2 0.1 5.9e-20 70.6 0.1 1.3 1 0 0 1 1 1 1 Alba Iron_traffic PF04362.9 EPE32042.1 - 0.0055 16.1 0.5 0.019 14.4 0.2 1.9 2 0 0 2 2 2 1 Bacterial Fe(2+) trafficking Zn_clus PF00172.13 EPE32044.1 - 0.0002 21.2 7.5 0.00034 20.4 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SBP56 PF05694.6 EPE32045.1 - 1.1e-05 24.0 0.0 0.0087 14.5 0.0 2.8 2 1 0 2 2 2 2 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 EPE32045.1 - 0.014 14.5 0.1 2.8 6.9 0.1 2.6 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller LVIVD PF08309.6 EPE32045.1 - 0.064 12.2 0.5 2 7.5 0.2 2.4 2 0 0 2 2 2 0 LVIVD repeat NHL PF01436.16 EPE32045.1 - 0.069 13.1 0.0 2.2 8.3 0.0 2.9 2 0 0 2 2 2 0 NHL repeat TP_methylase PF00590.15 EPE32046.1 - 2.9e-43 148.0 0.0 8.8e-43 146.4 0.0 1.9 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EPE32046.1 - 9.8e-12 45.0 0.0 2.5e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EPE32046.1 - 1.2e-09 37.3 0.1 8.1e-07 28.2 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EPE32046.1 - 3.9e-06 25.7 0.1 9.1e-06 24.5 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DASH_Spc19 PF08287.6 EPE32047.1 - 8.3e-45 152.1 1.5 1.1e-44 151.7 1.0 1.2 1 0 0 1 1 1 1 Spc19 Reo_sigmaC PF04582.7 EPE32047.1 - 0.15 11.2 3.2 0.22 10.6 2.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein HET PF06985.6 EPE32048.1 - 2.6e-32 111.8 0.1 4.5e-32 111.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Archease PF01951.11 EPE32048.1 - 0.14 12.1 0.0 4.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Archease protein family (MTH1598/TM1083) F-box-like PF12937.2 EPE32049.1 - 0.0026 17.4 0.7 0.014 15.0 0.6 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPE32049.1 - 0.013 15.1 0.5 0.03 13.9 0.4 1.6 1 0 0 1 1 1 0 F-box domain DUF989 PF06181.6 EPE32049.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF989) DUF3176 PF11374.3 EPE32050.1 - 1.4e-32 111.8 1.9 2.5e-32 111.0 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) MFS_1 PF07690.11 EPE32051.1 - 2.1e-48 164.8 53.9 1.2e-45 155.7 36.3 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Rsm22 PF09243.5 EPE32052.1 - 1.9e-31 109.1 0.0 2.1e-29 102.3 0.0 3.1 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Zn_clus PF00172.13 EPE32052.1 - 1.5e-05 24.8 9.7 1.5e-05 24.8 6.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE32052.1 - 0.00011 20.9 0.1 0.00023 19.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.16 EPE32053.1 - 1.4e-19 69.9 0.0 1.9e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase PGM_PMM_I PF02878.11 EPE32053.1 - 0.017 14.5 0.1 5.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I HET PF06985.6 EPE32054.1 - 4.3e-32 111.1 0.2 1.2e-31 109.7 0.2 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidohydro_3 PF07969.6 EPE32056.1 - 4.8e-60 203.8 0.0 6.6e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EPE32056.1 - 5e-05 23.1 0.0 0.00013 21.6 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family 2OG-FeII_Oxy_3 PF13640.1 EPE32057.1 - 1.5e-05 25.3 0.1 0.00012 22.5 0.0 2.4 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPE32057.1 - 0.00032 20.9 0.0 0.00084 19.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SIR2 PF02146.12 EPE32058.1 - 6.5e-56 188.8 0.0 1e-55 188.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EPE32058.1 - 0.0052 16.5 0.0 0.018 14.7 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Peptidase_M32 PF02074.10 EPE32058.1 - 0.0083 14.7 0.5 0.013 14.1 0.4 1.2 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase DUF3801 PF12687.2 EPE32058.1 - 0.25 10.8 5.1 0.37 10.3 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) NifU PF01106.12 EPE32059.1 - 0.0073 16.0 0.9 0.39 10.5 0.1 3.1 3 0 0 3 3 3 1 NifU-like domain TauD PF02668.11 EPE32060.1 - 7.6e-29 101.1 0.0 9.8e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EPE32060.1 - 1.3e-05 24.2 0.0 2.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 CsiD HET PF06985.6 EPE32061.1 - 1.5e-27 96.4 0.6 7.8e-27 94.1 0.4 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HsbA PF12296.3 EPE32062.1 - 0.00094 19.0 3.3 0.0026 17.6 0.9 2.1 1 1 1 2 2 2 1 Hydrophobic surface binding protein A DUF3814 PF12769.2 EPE32062.1 - 0.73 10.0 3.5 0.77 9.9 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3814) Pkinase PF00069.20 EPE32063.1 - 8.2e-09 34.9 0.0 1.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE32063.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 EPE32063.1 - 0.023 14.4 0.2 1 9.0 0.4 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EPE32063.1 - 0.044 12.8 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F1F0-ATPsyn_F PF10791.4 EPE32064.1 - 0.087 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi LRR_4 PF12799.2 EPE32064.1 - 0.56 9.9 18.1 39 4.0 0.1 7.6 7 3 2 9 9 9 0 Leucine Rich repeats (2 copies) NmrA PF05368.8 EPE32065.1 - 4.3e-28 98.1 0.0 5.2e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE32065.1 - 1e-15 58.2 0.7 1.5e-15 57.6 0.5 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE32065.1 - 0.00012 21.6 0.3 0.004 16.6 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE32065.1 - 0.00019 20.2 0.1 0.0004 19.1 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPE32065.1 - 0.021 14.7 2.5 0.021 14.7 1.7 1.8 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EPE32065.1 - 0.03 13.2 0.1 0.052 12.4 0.1 1.4 1 0 0 1 1 1 0 Male sterility protein KR PF08659.5 EPE32065.1 - 0.054 13.1 1.4 0.11 12.0 0.9 1.5 1 0 0 1 1 1 0 KR domain Bestrophin PF01062.16 EPE32066.1 - 1.7e-37 128.9 0.2 2.4e-37 128.4 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF3235 PF11574.3 EPE32067.1 - 0.056 13.6 1.1 0.12 12.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Tim17 PF02466.14 EPE32067.1 - 0.056 13.4 1.5 0.62 10.1 1.1 2.2 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Crystall_3 PF08964.5 EPE32067.1 - 0.062 13.0 0.4 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 Beta/Gamma crystallin Crystall PF00030.14 EPE32067.1 - 0.083 12.7 0.6 0.31 10.9 0.4 1.9 1 1 0 1 1 1 0 Beta/Gamma crystallin ATP-sulfurylase PF01747.12 EPE32068.1 - 8e-88 293.3 0.1 1.1e-87 292.8 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EPE32068.1 - 2.5e-54 183.1 0.0 3.8e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EPE32068.1 - 1.4e-52 177.3 0.0 2.2e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 EPE32068.1 - 0.05 13.4 0.1 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Complex1_LYR_1 PF13232.1 EPE32069.1 - 2.6e-20 72.3 4.2 3.5e-20 71.9 2.9 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EPE32069.1 - 2.9e-19 68.6 4.0 3.9e-19 68.1 2.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EPE32069.1 - 0.0065 16.9 2.3 0.0083 16.5 1.6 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Cnl2_NKP2 PF09447.5 EPE32069.1 - 0.04 13.5 1.1 0.98 9.1 0.0 2.3 2 0 0 2 2 2 0 Cnl2/NKP2 family protein ALS2CR8 PF15299.1 EPE32069.1 - 0.071 12.6 0.2 0.081 12.5 0.1 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DUF4653 PF15546.1 EPE32070.1 - 0.31 10.2 9.8 0.069 12.4 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) HAD PF12710.2 EPE32071.1 - 4.1e-15 56.4 0.1 6.2e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPE32071.1 - 1.9e-12 48.0 2.2 3.1e-11 44.0 1.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPE32071.1 - 2e-08 34.1 0.9 2.8e-07 30.3 0.1 2.5 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPE32071.1 - 4.2e-07 30.3 0.0 2e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPE32071.1 - 0.0011 18.2 0.0 0.051 12.7 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.7 EPE32071.1 - 0.0025 16.8 0.1 0.0037 16.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Acid_PPase PF12689.2 EPE32071.1 - 0.15 11.7 0.0 0.24 10.9 0.0 1.4 1 1 0 1 1 1 0 Acid Phosphatase PAPS_reduct PF01507.14 EPE32072.1 - 7.6e-41 139.8 0.0 1.2e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3494 PF11999.3 EPE32073.1 - 1.5e-42 145.5 18.5 1.5e-42 145.5 12.8 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3494) HET PF06985.6 EPE32075.1 - 3.2e-22 79.1 6.9 6.1e-20 71.7 4.8 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M28 PF04389.12 EPE32076.1 - 6.4e-36 123.7 0.0 1.1e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EPE32076.1 - 1.7e-13 50.0 0.5 4e-13 48.9 0.4 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EPE32076.1 - 5.3e-05 22.7 0.9 6e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EPE32076.1 - 0.0011 17.8 0.0 0.014 14.2 0.0 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase F-box-like PF12937.2 EPE32077.1 - 0.0027 17.3 0.6 0.0091 15.6 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPE32077.1 - 0.017 14.7 0.1 0.04 13.5 0.1 1.6 1 0 0 1 1 1 0 F-box domain p450 PF00067.17 EPE32078.1 - 4.5e-66 223.2 0.0 5.8e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3712 PF12505.3 EPE32079.1 - 9.3e-29 99.9 1.2 9.3e-29 99.9 0.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) ApoLp-III PF07464.6 EPE32080.1 - 0.0067 16.4 0.4 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Heme_oxygenase PF01126.15 EPE32080.1 - 0.013 15.0 0.2 0.019 14.5 0.1 1.3 1 1 0 1 1 1 0 Heme oxygenase Transcrip_act PF04949.8 EPE32080.1 - 0.075 12.6 0.1 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Transcriptional activator F-box-like PF12937.2 EPE32081.1 - 0.0015 18.1 0.4 0.006 16.2 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EPE32082.1 - 0.038 13.7 0.1 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 F-box-like Methyltransf_23 PF13489.1 EPE32083.1 - 0.00021 21.0 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE32083.1 - 0.0036 17.6 0.0 0.0058 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE32083.1 - 0.014 15.8 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EPE32083.1 - 0.032 14.7 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EPE32083.1 - 0.041 14.4 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain APH PF01636.18 EPE32084.1 - 6.3e-06 26.1 0.0 6.1e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE32084.1 - 0.00019 21.1 0.0 0.00045 19.8 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Asp_protease_2 PF13650.1 EPE32085.1 - 0.00024 21.5 0.1 0.0027 18.1 0.1 2.3 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.5 EPE32085.1 - 0.00039 19.9 0.2 0.079 12.5 0.0 2.3 1 1 1 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 EPE32085.1 - 0.002 17.8 0.1 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease DUF4064 PF13273.1 EPE32086.1 - 0.0096 16.0 0.5 0.02 14.9 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF3784 PF12650.2 EPE32086.1 - 0.053 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) CopD PF05425.8 EPE32086.1 - 1.5 9.0 8.9 0.16 12.1 1.7 2.2 2 0 0 2 2 2 0 Copper resistance protein D Hydrolase_6 PF13344.1 EPE32087.1 - 5.7e-28 96.7 0.0 1.3e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE32087.1 - 3.8e-18 64.9 0.3 3.8e-17 61.7 0.0 2.6 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 EPE32087.1 - 6e-09 36.3 0.0 0.0018 18.5 0.0 4.0 2 2 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPE32087.1 - 3.3e-06 27.6 0.0 0.47 10.8 0.0 3.7 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPE32087.1 - 0.029 14.5 0.0 0.49 10.5 0.0 2.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HET PF06985.6 EPE32089.1 - 6.4e-36 123.5 0.0 1e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3856 PF12968.2 EPE32089.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) HET PF06985.6 EPE32090.1 - 6.1e-32 110.6 0.6 1.1e-31 109.8 0.1 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.2 EPE32091.1 - 5.3e-18 65.7 0.5 7.1e-18 65.3 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE32091.1 - 4.6e-15 55.6 0.0 8.1e-15 54.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EPE32091.1 - 6.8e-12 44.5 0.0 3.9e-09 35.4 0.0 2.9 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 EPE32091.1 - 1.6e-08 34.3 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EPE32091.1 - 1.9e-07 30.5 0.2 7.1e-07 28.6 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EPE32091.1 - 0.00046 19.9 0.0 0.0012 18.6 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EPE32091.1 - 0.00071 18.9 0.0 0.0019 17.5 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EPE32091.1 - 0.0056 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EPE32091.1 - 0.095 12.2 0.1 0.13 11.7 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold FA_desaturase PF00487.19 EPE32093.1 - 0.033 13.6 2.7 0.059 12.8 1.9 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DUF3328 PF11807.3 EPE32096.1 - 2.1e-09 37.3 0.1 2.8e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) p450 PF00067.17 EPE32097.1 - 2.7e-36 125.0 0.0 1.1e-31 109.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Tyrosinase PF00264.15 EPE32098.1 - 3.2e-41 141.9 0.2 4.6e-41 141.4 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase IBR PF01485.16 EPE32099.1 - 2.1e-12 46.7 41.2 8.6e-08 31.9 6.4 3.9 3 0 0 3 3 3 2 IBR domain zf-CCCH PF00642.19 EPE32099.1 - 1.4e-11 43.7 15.0 5.4e-08 32.3 0.9 4.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EPE32099.1 - 0.00015 21.7 10.3 0.00015 21.7 7.1 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 EPE32099.1 - 0.00023 20.9 0.0 0.15 11.9 0.0 3.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EPE32099.1 - 0.00033 20.4 9.0 0.00033 20.4 6.3 4.1 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EPE32099.1 - 0.0029 17.2 10.4 0.0029 17.2 7.2 4.0 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.1 EPE32099.1 - 0.0079 16.1 4.2 0.0079 16.1 2.9 5.5 6 0 0 6 6 6 1 Zinc finger C-x8-C-x5-C-x3-H type zf-His_Me_endon PF05551.6 EPE32101.1 - 5.7e-11 42.5 3.3 8.8e-11 41.9 2.3 1.2 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease F-box-like PF12937.2 EPE32103.1 - 1.1e-07 31.4 1.8 1.1e-07 31.4 1.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPE32103.1 - 0.00022 20.7 0.1 0.017 14.8 0.0 3.1 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.2 EPE32103.1 - 0.28 10.8 3.0 0.72 9.5 0.2 2.8 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) SIP1 PF04938.7 EPE32104.1 - 1.7e-05 24.2 0.0 0.0001 21.7 0.0 2.2 2 1 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Amidohydro_2 PF04909.9 EPE32108.1 - 1.5e-27 96.9 0.3 1.8e-27 96.5 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase ketoacyl-synt PF00109.21 EPE32109.1 - 2.6e-70 236.8 0.0 6.4e-70 235.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPE32109.1 - 2.7e-48 164.9 0.0 5e-48 164.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EPE32109.1 - 1.9e-34 118.0 0.6 4.2e-34 116.9 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EPE32109.1 - 1.9e-28 100.2 0.0 8.1e-28 98.1 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EPE32109.1 - 2.5e-19 69.3 3.1 7.1e-10 39.0 0.3 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EPE32109.1 - 8.5e-17 61.2 0.0 2.3e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 EPE32109.1 - 1.6e-07 31.4 10.0 1.6e-06 28.1 0.2 4.1 5 0 0 5 5 5 2 Alpha/beta hydrolase family Podoplanin PF05808.6 EPE32110.1 - 0.00058 19.4 1.6 0.001 18.6 1.1 1.3 1 0 0 1 1 1 1 Podoplanin FMN_bind PF04205.9 EPE32110.1 - 0.0073 16.4 3.1 0.015 15.4 2.1 1.5 1 0 0 1 1 1 1 FMN-binding domain ABC2_membrane_3 PF12698.2 EPE32110.1 - 0.0081 15.2 1.8 0.011 14.8 1.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4366 PF14283.1 EPE32110.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) VSP PF03302.8 EPE32110.1 - 0.078 11.6 0.1 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein IncA PF04156.9 EPE32110.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 IncA protein Mucin PF01456.12 EPE32110.1 - 7.3 6.3 23.4 15 5.3 16.2 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein BTB PF00651.26 EPE32112.1 - 0.00082 19.3 0.1 0.0027 17.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Glyco_hydro_11 PF00457.12 EPE32113.1 - 1.3e-66 223.4 15.6 1.5e-66 223.2 10.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 MFS_1 PF07690.11 EPE32114.1 - 2.3e-45 154.8 27.4 2.3e-45 154.8 19.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EPE32114.1 - 1.1 9.6 2.5 1.1 9.7 0.3 2.0 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) BTB PF00651.26 EPE32115.1 - 1.9e-13 50.3 0.0 3.3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PCI PF01399.22 EPE32116.1 - 1.2e-20 73.7 0.1 4.5e-20 71.9 0.0 2.0 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EPE32116.1 - 0.085 12.6 1.0 0.19 11.4 0.0 2.1 3 0 0 3 3 3 0 COP9 signalosome, subunit CSN8 HhH-GPD PF00730.20 EPE32116.1 - 0.13 12.5 0.8 17 5.7 0.1 2.8 3 1 0 3 3 3 0 HhH-GPD superfamily base excision DNA repair protein FSH1 PF03959.8 EPE32117.1 - 2.6e-57 193.6 0.0 3.4e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EPE32117.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cys_Met_Meta_PP PF01053.15 EPE32119.1 - 5e-23 81.0 0.0 6.5e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPE32119.1 - 8.3e-06 24.9 0.0 1.7e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Pyr_redox_3 PF13738.1 EPE32120.1 - 8.5e-19 68.4 0.1 1.4e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE32120.1 - 3.9e-15 55.0 0.1 1e-14 53.6 0.1 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EPE32120.1 - 1.1e-09 38.1 0.0 4.3e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE32120.1 - 5.9e-05 22.1 0.0 0.034 13.0 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EPE32120.1 - 0.00043 19.2 0.0 0.002 17.1 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPE32120.1 - 0.0091 15.7 0.2 0.17 11.6 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EPE32120.1 - 0.028 13.5 0.1 0.076 12.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.10 EPE32120.1 - 0.06 11.5 0.3 1.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) MFS_1 PF07690.11 EPE32121.1 - 6.2e-25 87.6 25.2 6.2e-25 87.6 17.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.6 EPE32121.1 - 0.00016 21.4 9.5 0.0004 20.1 0.1 3.6 3 1 0 3 3 3 2 Domain of unknown function (DUF1772) Phage_T4_gp19 PF06841.7 EPE32121.1 - 0.045 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 MFS_1 PF07690.11 EPE32122.1 - 7.8e-30 103.7 29.2 2.1e-29 102.3 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 2TM PF13239.1 EPE32122.1 - 0.031 14.3 0.2 0.031 14.3 0.1 4.6 3 1 0 3 3 3 0 2TM domain Bac_luciferase PF00296.15 EPE32123.1 - 2.5e-63 214.0 0.0 3.4e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase PAN_4 PF14295.1 EPE32124.1 - 0.0018 17.9 0.5 0.0043 16.7 0.3 1.7 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 EPE32124.1 - 0.0093 15.5 1.0 0.022 14.3 0.7 1.6 1 0 0 1 1 1 1 PAN-like domain PAN_1 PF00024.21 EPE32124.1 - 0.029 14.1 0.5 0.065 12.9 0.4 1.6 1 0 0 1 1 1 0 PAN domain DUF1049 PF06305.6 EPE32124.1 - 0.36 10.3 1.5 0.64 9.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) adh_short PF00106.20 EPE32125.1 - 5.6e-10 39.3 0.0 7.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE32125.1 - 5.3e-06 26.2 0.0 4.3e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EPE32125.1 - 0.00037 20.0 0.0 0.00043 19.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EPE32125.1 - 0.0055 16.5 0.1 0.0078 16.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EPE32125.1 - 0.0068 15.3 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Radical_SAM PF04055.16 EPE32126.1 - 2.1e-13 50.7 0.0 4.4e-13 49.7 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily ERG2_Sigma1R PF04622.7 EPE32127.1 - 1.9e-90 301.8 1.4 2.1e-90 301.7 1.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF4360 PF14273.1 EPE32128.1 - 1.5e-56 190.9 3.6 2e-56 190.5 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) adh_short PF00106.20 EPE32129.1 - 2.5e-16 60.0 0.0 8.8e-16 58.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE32129.1 - 4.7e-05 23.2 0.0 0.00018 21.3 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE32129.1 - 5.3e-05 22.9 0.0 0.0017 18.0 0.0 2.1 2 0 0 2 2 2 1 KR domain CorA PF01544.13 EPE32131.1 - 2.2e-06 26.9 1.0 5.6e-06 25.6 0.3 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Abhydrolase_3 PF07859.8 EPE32132.1 - 7e-28 97.6 0.0 9.3e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EPE32132.1 - 3.1e-13 49.1 0.0 5.8e-13 48.2 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPE32132.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE32132.1 - 0.15 11.2 0.1 0.55 9.4 0.1 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF4238 PF14022.1 EPE32133.1 - 5.1e-31 107.9 0.0 8.4e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Acyl_transf_1 PF00698.16 EPE32134.1 - 8.2e-88 294.7 0.0 1.4e-87 293.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EPE32134.1 - 3.1e-80 269.3 0.0 5.9e-80 268.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EPE32134.1 - 6e-55 185.7 0.0 1.2e-54 184.7 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EPE32134.1 - 1.6e-46 158.3 0.0 3.2e-46 157.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPE32134.1 - 1.6e-38 131.2 2.1 3.7e-38 130.0 0.8 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EPE32134.1 - 5.3e-13 48.7 0.2 1.8e-12 47.0 0.1 1.9 1 1 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EPE32134.1 - 8.1e-12 45.2 0.0 1.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EPE32134.1 - 0.00011 21.2 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain FAD_binding_3 PF01494.14 EPE32135.1 - 1.5e-16 60.3 6.2 1.1e-10 41.1 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EPE32135.1 - 9.2e-05 22.3 0.7 0.00026 20.9 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPE32135.1 - 0.00018 21.2 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.5 EPE32135.1 - 0.00029 19.7 0.0 0.002 17.0 0.0 2.1 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 EPE32135.1 - 0.0071 16.7 0.7 0.033 14.5 0.3 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE32135.1 - 0.012 15.5 0.1 0.022 14.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ACP_syn_III_C PF08541.5 EPE32135.1 - 0.024 14.6 0.5 8.4 6.4 0.3 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DAO PF01266.19 EPE32135.1 - 0.041 12.7 1.8 0.072 11.9 1.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EPE32135.1 - 0.12 12.0 0.4 0.25 11.0 0.1 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Tyrosinase PF00264.15 EPE32136.1 - 1.5e-36 126.6 0.0 5.3e-36 124.8 0.0 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.11 EPE32137.1 - 7.6e-41 139.9 57.7 9.7e-41 139.6 32.3 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily PepSY_TM_2 PF13703.1 EPE32138.1 - 0.5 10.5 6.2 6.8 6.9 0.2 3.1 2 1 1 3 3 3 0 PepSY-associated TM helix zf-C2H2_4 PF13894.1 EPE32140.1 - 0.0091 16.2 0.4 0.016 15.4 0.3 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE32140.1 - 0.047 14.0 0.6 0.08 13.3 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type HET PF06985.6 EPE32141.1 - 2.4e-16 60.1 0.0 4.2e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Chitin_bind_1 PF00187.14 EPE32143.1 - 0.0024 17.8 14.1 0.005 16.7 9.8 1.6 1 1 0 1 1 1 1 Chitin recognition protein NMO PF03060.10 EPE32144.1 - 1.8e-42 145.6 3.4 3.9e-32 111.7 0.4 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 EPE32144.1 - 6.9e-09 35.0 0.0 0.00043 19.2 1.5 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EPE32144.1 - 1.6e-07 30.5 1.5 2.6e-07 29.8 1.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EPE32144.1 - 2.2e-07 30.1 0.2 3.3e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NAD_binding_1 PF00175.16 EPE32145.1 - 1.3e-09 38.5 0.0 2.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 EPE32145.1 - 5.4e-09 36.3 0.0 9.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.19 EPE32145.1 - 2.7e-07 30.6 0.0 4.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 EPE32145.1 - 0.00094 18.8 0.1 0.0021 17.7 0.0 1.5 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 EPE32145.1 - 0.014 15.3 1.0 0.97 9.3 0.1 3.1 2 1 0 3 3 3 0 Ferric reductase NAD binding domain DUF2315 PF10231.4 EPE32145.1 - 0.081 12.7 0.8 0.17 11.7 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2315) ATP_bind_3 PF01171.15 EPE32145.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Zn_clus PF00172.13 EPE32146.1 - 7.2e-11 41.8 9.2 1.4e-10 40.9 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE32146.1 - 6.8e-06 25.1 0.6 1.2e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EPE32147.1 - 1.9e-43 148.5 30.7 1.9e-43 148.5 21.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE32147.1 - 4.5e-11 42.0 23.7 5.7e-10 38.3 16.4 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter Cutinase PF01083.17 EPE32148.1 - 2.4e-29 102.3 4.2 3.8e-29 101.6 2.9 1.3 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EPE32148.1 - 0.0012 18.3 0.8 0.0019 17.6 0.0 1.7 2 0 0 2 2 2 1 PE-PPE domain ADH_zinc_N PF00107.21 EPE32149.1 - 3.2e-10 39.6 0.1 6.2e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE32149.1 - 2e-09 37.2 0.7 1.9e-08 34.0 0.4 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain SM-ATX PF14438.1 EPE32149.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 1 0 1 1 1 0 Ataxin 2 SM domain HrpA_pilin PF09589.5 EPE32150.1 - 4.4 7.7 8.2 0.22 11.9 0.8 2.2 2 0 0 2 2 2 0 HrpA pilus formation protein DUF4470 PF14737.1 EPE32151.1 - 4.2e-21 74.5 0.0 8.2e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_MLP1_2 PF07926.7 EPE32152.1 - 0.023 14.4 30.4 0.11 12.2 3.7 4.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.8 EPE32152.1 - 2.4 7.6 25.5 0.81 9.1 5.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) V_ATPase_I PF01496.14 EPE32152.1 - 3.5 5.3 21.8 7 4.3 15.1 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HTH_OrfB_IS605 PF12323.3 EPE32153.1 - 0.0089 15.3 0.2 0.61 9.4 0.1 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain XhlA PF10779.4 EPE32153.1 - 0.027 14.3 0.3 0.061 13.2 0.2 1.6 1 0 0 1 1 1 0 Haemolysin XhlA AAA_11 PF13086.1 EPE32156.1 - 2.1e-13 50.4 0.0 5.9e-13 48.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE32156.1 - 8.2e-09 35.1 0.0 1.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPE32156.1 - 1.6e-05 24.5 0.0 0.00012 21.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EPE32156.1 - 4e-05 23.0 0.0 8.2e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPE32156.1 - 0.0033 16.8 0.0 0.0083 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE32156.1 - 0.0056 17.4 0.0 0.019 15.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPE32156.1 - 0.048 13.7 0.1 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EPE32156.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 EPE32156.1 - 0.11 12.1 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 NTPase T2SE PF00437.15 EPE32156.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.10 EPE32156.1 - 0.19 10.3 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Abhydrolase_5 PF12695.2 EPE32159.1 - 2e-05 24.3 0.1 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EPE32159.1 - 0.013 14.9 0.2 0.055 12.8 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 EPE32159.1 - 0.035 13.3 0.3 0.089 12.0 0.2 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EPE32159.1 - 0.039 13.4 0.2 0.11 11.9 0.1 1.8 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EPE32159.1 - 0.058 13.2 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_35 PF01301.14 EPE32160.1 - 3.1e-90 302.7 0.8 3.8e-90 302.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 EPE32160.1 - 6.2e-09 35.4 0.4 3.2e-08 33.0 0.3 1.9 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 EPE32160.1 - 4.2e-08 33.4 0.0 4.6e-06 26.8 0.0 2.9 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Glyoxalase PF00903.20 EPE32160.1 - 0.0055 16.6 0.1 0.53 10.2 0.0 2.3 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3158 PF11358.3 EPE32161.1 - 0.0031 17.0 0.5 0.0064 16.0 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3158) DUF4618 PF15397.1 EPE32161.1 - 0.018 14.3 0.9 0.032 13.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Luteo_P1-P2 PF08467.5 EPE32161.1 - 0.02 13.7 0.1 4 6.1 0.0 2.1 2 0 0 2 2 2 0 Luteovirus RNA polymerase P1-P2/replicase TBPIP PF07106.8 EPE32161.1 - 0.041 13.4 1.2 0.1 12.1 0.9 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FliT PF05400.8 EPE32161.1 - 0.06 13.7 2.1 0.15 12.5 1.5 1.7 1 0 0 1 1 1 0 Flagellar protein FliT ERM PF00769.14 EPE32161.1 - 0.082 12.4 2.9 0.15 11.5 2.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF2390 PF09523.5 EPE32161.1 - 1 9.5 6.3 3.6 7.8 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2390) Fib_alpha PF08702.5 EPE32161.1 - 1.3 9.1 4.7 0.49 10.5 1.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_11 PF13086.1 EPE32162.1 - 7.6e-23 81.3 0.0 1.4e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EPE32162.1 - 2.2e-15 56.5 0.0 4.2e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE32162.1 - 2.8e-08 33.3 0.1 1e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EPE32162.1 - 0.00014 21.4 0.0 0.003 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain zf-CCCH PF00642.19 EPE32162.1 - 0.00022 20.8 3.5 0.00041 19.9 2.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ResIII PF04851.10 EPE32162.1 - 0.00037 20.3 0.0 0.00096 19.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EPE32162.1 - 0.0017 17.4 0.2 0.0038 16.2 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EPE32162.1 - 0.029 13.6 0.0 0.087 12.0 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.1 EPE32162.1 - 0.033 14.1 0.1 0.09 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.16 EPE32162.1 - 0.035 13.2 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EPE32162.1 - 0.1 11.9 0.1 0.28 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EPE32162.1 - 0.14 12.3 0.8 0.82 9.8 0.5 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) p450 PF00067.17 EPE32163.1 - 1.8e-55 188.2 0.0 2.4e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 EPE32164.1 - 1.6e-20 72.8 0.0 3.2e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE32164.1 - 3.9e-10 39.3 0.1 2.6e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EPE32164.1 - 0.0034 16.9 0.1 0.0034 16.9 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated FAD_binding_2 PF00890.19 EPE32164.1 - 0.0054 15.6 0.1 0.0083 15.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EPE32164.1 - 0.026 12.9 0.1 0.036 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_114 PF03537.8 EPE32165.1 - 9e-23 79.8 0.1 1.5e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Glyco_hydro_31 PF01055.21 EPE32167.1 - 1.9e-167 557.6 5.2 2.3e-167 557.3 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EPE32167.1 - 2.2e-09 37.0 0.4 7.3e-09 35.3 0.3 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Lipoxygenase PF00305.14 EPE32168.1 - 2.1e-29 102.0 0.0 2.9e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase FaeA PF04703.7 EPE32168.1 - 0.0034 17.5 0.2 1.1 9.4 0.0 2.4 2 0 0 2 2 2 2 FaeA-like protein RTA1 PF04479.8 EPE32169.1 - 1e-51 175.5 11.3 1.3e-51 175.2 7.9 1.1 1 0 0 1 1 1 1 RTA1 like protein dsDNA_bind PF01984.15 EPE32170.1 - 5.8e-28 97.0 5.2 7.6e-28 96.6 3.6 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Coq4 PF05019.8 EPE32171.1 - 2.6e-98 327.3 0.0 3.1e-98 327.1 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.23 EPE32172.1 - 2.5e-13 50.6 0.0 3.9e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 SET domain SURF2 PF05477.6 EPE32172.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RRM_6 PF14259.1 EPE32173.1 - 3.8e-07 30.0 0.0 7.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE32173.1 - 0.0003 20.3 0.0 0.00059 19.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE32173.1 - 0.0009 19.0 0.1 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SecE PF00584.15 EPE32174.1 - 8.3e-14 50.9 0.0 9.3e-14 50.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Fungal_trans_2 PF11951.3 EPE32175.1 - 0.00052 18.7 1.8 0.00052 18.7 1.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1992 PF09350.5 EPE32176.1 - 6.4e-24 83.5 0.2 1.7e-23 82.1 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) RPAP1_N PF08621.5 EPE32176.1 - 0.0098 15.4 1.0 0.027 14.0 0.0 2.2 2 0 0 2 2 2 1 RPAP1-like, N-terminal Microtub_assoc PF07989.6 EPE32178.1 - 0.0009 19.0 4.4 0.0022 17.7 3.0 1.7 1 0 0 1 1 1 1 Microtubule associated BLOC1_2 PF10046.4 EPE32178.1 - 0.23 11.5 5.1 0.65 10.1 3.5 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 EPE32178.1 - 3 7.3 11.9 7.2 6.1 8.3 1.7 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 EPE32179.1 - 1.7e-25 89.6 0.0 3e-25 88.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE32179.1 - 2.6e-08 33.2 0.1 2e-07 30.3 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Laminin_EGF PF00053.19 EPE32180.1 - 0.031 14.2 3.9 0.031 14.2 2.7 2.1 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) Ricin_B_lectin PF00652.17 EPE32181.1 - 8.5e-17 61.3 0.0 1.6e-05 24.9 0.0 3.8 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EPE32181.1 - 0.14 12.5 0.0 1.6 9.1 0.0 2.6 2 2 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like DPBB_1 PF03330.13 EPE32182.1 - 5.3e-07 29.5 0.7 8.3e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EPE32182.1 - 0.00026 20.6 0.5 0.00046 19.8 0.3 1.3 1 0 0 1 1 1 1 Barwin family ETRAMP PF09716.5 EPE32182.1 - 0.14 12.0 2.8 0.29 11.1 1.9 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NmrA PF05368.8 EPE32183.1 - 3.8e-34 117.9 0.0 4.8e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE32183.1 - 1.4e-17 64.2 0.0 1.7e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE32183.1 - 6e-05 22.5 0.0 8.4e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE32183.1 - 0.00051 18.8 0.0 0.00078 18.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPE32183.1 - 0.041 13.7 0.1 0.06 13.2 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPE32183.1 - 0.083 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EPE32183.1 - 0.098 11.5 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein GCFC PF07842.7 EPE32184.1 - 2.1e-76 256.9 5.2 2.1e-76 256.9 3.6 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 EPE32184.1 - 3.2e-16 59.3 12.8 3.2e-16 59.3 8.9 2.8 3 0 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.18 EPE32184.1 - 3e-13 49.3 5.5 6.6e-13 48.2 3.8 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EPE32184.1 - 8.6e-09 35.1 2.5 5.6e-08 32.5 0.6 2.8 2 0 0 2 2 2 1 DExH-box splicing factor binding site MSP1b PF03429.8 EPE32184.1 - 0.03 12.2 0.0 0.049 11.5 0.0 1.2 1 0 0 1 1 1 0 Major surface protein 1B NOA36 PF06524.7 EPE32184.1 - 1.3 8.1 5.5 2.4 7.3 3.8 1.3 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.27 EPE32185.1 - 6.4e-80 260.4 20.3 4.1e-13 48.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EPE32185.1 - 4.1e-08 31.8 2.2 0.00051 18.3 0.1 4.7 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPE32185.1 - 9.6e-07 27.8 0.3 0.4 9.3 0.0 3.4 2 1 0 3 3 3 3 Nup133 N terminal like bZIP_1 PF00170.16 EPE32185.1 - 0.28 11.1 2.3 0.22 11.4 0.2 1.8 2 0 0 2 2 2 0 bZIP transcription factor HEAT PF02985.17 EPE32186.1 - 3.9e-06 26.4 0.3 0.23 11.6 0.0 5.9 7 0 0 7 7 7 1 HEAT repeat CLASP_N PF12348.3 EPE32186.1 - 0.00022 20.6 0.1 0.0019 17.5 0.0 2.1 2 0 0 2 2 2 1 CLASP N terminal IncA PF04156.9 EPE32186.1 - 0.00086 18.9 0.5 0.00086 18.9 0.4 1.7 2 0 0 2 2 2 1 IncA protein TPR_MLP1_2 PF07926.7 EPE32186.1 - 0.0033 17.1 0.3 0.0033 17.1 0.2 2.8 4 0 0 4 4 4 1 TPR/MLP1/MLP2-like protein MMS19_N PF14500.1 EPE32186.1 - 0.018 14.3 0.7 0.09 12.0 0.2 2.2 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Proteasom_PSMB PF10508.4 EPE32186.1 - 0.039 12.2 0.5 2.9 6.0 0.0 2.6 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit APG6 PF04111.7 EPE32186.1 - 0.055 12.5 10.7 0.02 13.9 4.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Med14 PF08638.6 EPE32186.1 - 0.08 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit MED14 HsbA PF12296.3 EPE32186.1 - 0.11 12.3 0.4 1.9 8.3 0.0 2.9 3 0 0 3 3 3 0 Hydrophobic surface binding protein A RepB PF07506.6 EPE32186.1 - 1.7 8.4 9.6 0.2 11.4 1.4 3.0 2 1 1 3 3 3 0 RepB plasmid partitioning protein PH_10 PF15411.1 EPE32188.1 - 1.9e-37 127.9 0.4 4.5e-34 117.1 0.1 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain RhoGEF PF00621.15 EPE32188.1 - 1.5e-32 112.9 0.0 3e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EPE32188.1 - 1.6e-09 37.2 0.0 4.5e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 EPE32188.1 - 0.0046 17.1 0.1 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 PH domain FIVAR PF07554.8 EPE32188.1 - 0.0099 16.0 0.3 0.048 13.9 0.2 2.2 1 0 0 1 1 1 1 Uncharacterised Sugar-binding Domain CDC24 PF06395.6 EPE32189.1 - 6.6e-24 83.7 0.0 1.2e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin WD40 PF00400.27 EPE32190.1 - 5.6e-39 130.6 6.1 1.7e-06 27.6 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EPE32190.1 - 8.6e-09 34.9 2.8 1.3e-08 34.4 0.6 2.1 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 EPE32190.1 - 2.3e-06 26.0 2.7 0.025 12.7 0.1 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 F-box PF00646.28 EPE32190.1 - 0.00017 21.1 0.6 0.0019 17.8 0.1 2.3 1 1 1 2 2 2 1 F-box domain BBS2_Mid PF14783.1 EPE32190.1 - 0.0012 18.5 0.1 2.2 8.0 0.0 4.0 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region MgtE_N PF03448.12 EPE32190.1 - 0.068 13.5 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 MgtE intracellular N domain Aa_trans PF01490.13 EPE32191.1 - 6.5e-32 110.5 20.3 1e-31 109.8 14.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IBR PF01485.16 EPE32192.1 - 2e-15 56.3 25.2 2.5e-09 36.8 1.9 3.5 3 0 0 3 3 3 2 IBR domain P16-Arc PF04699.9 EPE32194.1 - 4.2e-58 195.6 0.0 4.9e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF4066 PF13278.1 EPE32195.1 - 1.9e-19 69.5 0.0 3.9e-19 68.5 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EPE32195.1 - 2.9e-09 36.5 0.0 4.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Adaptin_N PF01602.15 EPE32197.1 - 5.9e-116 387.8 9.7 7.3e-116 387.5 6.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EPE32197.1 - 5e-44 148.8 0.0 1.1e-43 147.7 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EPE32197.1 - 2.6e-19 69.6 0.0 5.2e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Methyltransf_11 PF08241.7 EPE32198.1 - 1e-09 38.7 0.0 2.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE32198.1 - 5.1e-09 36.0 0.0 7.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE32198.1 - 5.8e-07 29.9 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE32198.1 - 0.00062 19.3 0.0 0.0014 18.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE32198.1 - 0.02 15.2 0.0 0.035 14.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EPE32198.1 - 0.025 13.6 0.0 0.061 12.4 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family LMF1 PF06762.9 EPE32200.1 - 0.041 12.6 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Lipase maturation factor TMEM154 PF15102.1 EPE32200.1 - 0.14 11.8 4.0 0.72 9.5 2.8 2.0 1 1 0 1 1 1 0 TMEM154 protein family PALP PF00291.20 EPE32203.1 - 3.2e-58 197.3 0.4 3.7e-58 197.1 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aminotran_1_2 PF00155.16 EPE32203.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2620 PF10941.3 EPE32203.1 - 0.68 9.9 3.7 0.38 10.7 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function DUF2620 PRANC PF09372.5 EPE32204.1 - 0.13 12.2 3.0 0.37 10.7 0.0 2.9 3 0 0 3 3 3 0 PRANC domain HET PF06985.6 EPE32206.1 - 1.4e-26 93.3 0.0 2.4e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.18 EPE32207.1 - 1e-14 54.8 0.0 1.8e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE32207.1 - 0.0095 15.5 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPE32207.1 - 0.041 13.0 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.6 EPE32207.1 - 0.09 11.3 0.0 0.17 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DJ-1_PfpI PF01965.19 EPE32209.1 - 2e-23 82.4 0.1 3.8e-23 81.5 0.1 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EPE32209.1 - 1.6e-19 69.1 0.1 3.6e-19 67.9 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Sod_Fe_C PF02777.13 EPE32211.1 - 7e-38 128.7 0.7 1.3e-37 127.8 0.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EPE32211.1 - 6.1e-30 103.3 1.3 1.3e-29 102.2 0.9 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sld5 PF05916.6 EPE32212.1 - 1.3e-15 57.6 0.0 1.7e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Metallophos_2 PF12850.2 EPE32213.1 - 0.14 12.0 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_72 PF03198.9 EPE32215.1 - 1.1e-103 346.4 0.2 1.6e-103 345.9 0.1 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EPE32215.1 - 1.1e-06 28.0 0.2 0.0056 15.9 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EPE32215.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain adh_short PF00106.20 EPE32216.1 - 2.6e-22 79.5 0.0 5.3e-22 78.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE32216.1 - 8.9e-08 31.9 0.0 6.6e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EPE32216.1 - 2.9e-07 30.5 0.0 6.4e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EPE32216.1 - 0.058 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F-box-like PF12937.2 EPE32217.1 - 0.0022 17.6 1.0 0.017 14.8 0.1 2.8 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EPE32217.1 - 2.2 8.0 5.4 3 7.5 0.3 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Pirin PF02678.11 EPE32219.1 - 2.7e-32 110.8 0.0 4.9e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EPE32219.1 - 9.1e-24 83.5 0.0 2e-22 79.1 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EPE32219.1 - 1.2e-06 27.9 0.3 7.8e-05 22.1 0.1 2.3 2 0 0 2 2 2 1 Cupin domain DUF2672 PF10878.3 EPE32220.1 - 0.058 13.1 0.4 0.21 11.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2672) zf-C2H2_4 PF13894.1 EPE32222.1 - 8.8 6.9 8.0 1.7 9.1 1.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Abhydrolase_3 PF07859.8 EPE32223.1 - 2.2e-17 63.3 0.0 6.1e-17 61.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE32223.1 - 8e-12 44.8 0.0 0.0001 21.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE32223.1 - 1.3e-10 41.1 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE32223.1 - 6.2e-06 26.2 0.1 9.6e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EPE32223.1 - 1.3e-05 24.1 0.0 8.7e-05 21.4 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family AXE1 PF05448.7 EPE32223.1 - 3.2e-05 22.5 0.1 0.024 13.1 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 EPE32223.1 - 5.2e-05 22.2 0.0 7.4e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPE32223.1 - 0.0011 17.8 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase BAAT_C PF08840.6 EPE32223.1 - 0.005 16.5 0.0 0.014 15.0 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2424 PF10340.4 EPE32223.1 - 0.029 13.0 0.0 0.19 10.3 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) PRKCSH PF07915.8 EPE32224.1 - 2.8e-19 69.6 3.2 4.3e-19 69.1 0.1 2.9 4 0 0 4 4 4 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EPE32224.1 - 0.0053 16.2 0.2 0.054 12.9 0.1 2.3 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Sugar_tr PF00083.19 EPE32227.1 - 3.2e-74 250.1 14.0 1.9e-41 142.1 2.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPE32227.1 - 2.8e-28 98.6 14.4 2.2e-13 49.6 0.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Vfa1 PF08432.5 EPE32227.1 - 7.5 6.5 15.2 0.24 11.3 5.9 1.8 2 1 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Ank_2 PF12796.2 EPE32228.1 - 7.4e-25 87.1 0.3 8.4e-17 61.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE32228.1 - 4.8e-20 70.2 0.0 1.8e-08 33.7 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EPE32228.1 - 8.6e-18 62.6 0.2 1.5e-07 30.9 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EPE32228.1 - 1.4e-16 60.4 0.1 3.6e-10 40.0 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE32228.1 - 1.5e-15 56.8 0.1 1.3e-09 37.9 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Glyco_hydro_10 PF00331.15 EPE32229.1 - 9e-95 317.3 0.2 1.1e-94 317.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EPE32229.1 - 7.2e-12 44.7 11.6 1.6e-11 43.6 8.1 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Fungal_trans_2 PF11951.3 EPE32230.1 - 1.6e-07 30.2 0.3 3.3e-07 29.2 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE32230.1 - 0.0028 17.5 11.8 0.005 16.7 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE32231.1 - 1.6e-32 112.5 57.9 1.2e-30 106.4 9.1 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Acetyltransf_8 PF13523.1 EPE32232.1 - 2.9e-39 134.3 0.0 4.8e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPE32232.1 - 0.019 15.1 0.4 0.044 13.9 0.0 1.8 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain DUF607 PF04678.8 EPE32234.1 - 3.8e-42 144.2 3.8 7.3e-42 143.3 0.6 2.8 2 1 0 2 2 2 1 Protein of unknown function, DUF607 RNase_H2_suC PF08615.6 EPE32234.1 - 0.9 9.3 5.4 0.57 10.0 0.1 2.8 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Transket_pyr PF02779.19 EPE32235.1 - 2e-64 216.3 0.0 3.3e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EPE32235.1 - 2e-56 190.9 0.0 2.7e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component BSD PF03909.12 EPE32236.1 - 1.3e-24 85.6 3.3 4.6e-13 48.6 0.1 2.7 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EPE32236.1 - 8.3e-22 76.6 0.0 3.8e-21 74.5 0.0 2.1 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain GAS PF13851.1 EPE32236.1 - 0.035 13.2 0.6 0.094 11.8 0.4 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF816 PF05674.7 EPE32239.1 - 0.05 13.3 0.5 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF816) DUF1798 PF08807.5 EPE32239.1 - 0.53 10.0 3.8 1.4 8.6 0.8 2.4 1 1 1 2 2 2 0 Bacterial domain of unknown function (DUF1798) Pectate_lyase PF03211.8 EPE32240.1 - 5.6e-64 215.4 4.7 5.6e-64 215.4 3.3 2.1 2 0 0 2 2 2 1 Pectate lyase SAPS PF04499.10 EPE32240.1 - 0.09 11.3 0.3 0.11 11.1 0.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2413 PF10310.4 EPE32240.1 - 2.2 7.0 15.9 3.6 6.3 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Catalase PF00199.14 EPE32241.1 - 5.7e-165 548.6 0.3 7.7e-165 548.2 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EPE32241.1 - 4.1e-16 58.5 0.0 9.1e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive YscO PF07321.7 EPE32241.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO Fungal_trans PF04082.13 EPE32242.1 - 5.3e-15 54.9 3.6 7.4e-15 54.5 2.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.16 EPE32243.1 - 3.4e-137 457.6 40.0 4.2e-137 457.3 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE32243.1 - 6.8e-37 127.0 37.9 9.7e-37 126.4 26.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF202 PF02656.10 EPE32244.1 - 2 8.7 5.2 2.4 8.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Cation_ATPase_C PF00689.16 EPE32244.1 - 4.7 6.6 8.9 1.2 8.6 0.1 3.0 1 1 1 3 3 3 0 Cation transporting ATPase, C-terminus DUF4360 PF14273.1 EPE32245.1 - 4.2e-13 49.3 0.1 5.8e-13 48.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF1751 PF08551.5 EPE32246.1 - 1.3e-06 28.6 0.1 2.3e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EPE32246.1 - 0.0019 18.2 0.9 0.0032 17.5 0.6 1.5 1 0 0 1 1 1 1 Rhomboid family Prenyltransf PF01255.14 EPE32247.1 - 9.7e-87 289.7 0.0 1.5e-86 289.1 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4393 PF14337.1 EPE32247.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) PHD PF00628.24 EPE32248.1 - 2.5e-09 36.6 8.2 4e-09 36.0 5.7 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EPE32248.1 - 1.3e-07 31.8 2.0 9e-07 29.1 0.1 2.7 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 EPE32248.1 - 0.047 13.8 0.6 0.12 12.5 0.4 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 EPE32248.1 - 0.25 10.6 3.1 0.46 9.8 2.2 1.4 1 0 0 1 1 1 0 PHD-finger LRR_6 PF13516.1 EPE32249.1 - 0.00086 19.1 1.4 6.4 7.1 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 EPE32249.1 - 0.0079 15.7 8.3 2.3 7.9 0.0 4.6 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE32249.1 - 1.4 8.7 9.6 1.5 8.6 0.2 4.3 5 1 1 6 6 6 0 Leucine rich repeat LRR_7 PF13504.1 EPE32249.1 - 2.4 8.7 8.2 1.2e+02 3.5 0.2 5.8 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 EPE32249.1 - 6.6 7.1 9.2 14 6.1 0.1 5.1 6 0 0 6 6 6 0 Leucine Rich Repeat Sec62 PF03839.11 EPE32250.1 - 0.072 12.4 2.1 0.12 11.7 1.5 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 NARP1 PF12569.3 EPE32250.1 - 0.21 10.3 6.0 0.28 9.8 4.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2011 PF09428.5 EPE32250.1 - 0.41 10.5 15.9 0.22 11.3 9.1 2.0 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) RR_TM4-6 PF06459.7 EPE32250.1 - 2.4 8.0 6.5 3.4 7.4 4.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ADH_zinc_N PF00107.21 EPE32252.1 - 1.8e-10 40.4 0.1 2.9e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE32252.1 - 4e-10 39.4 0.6 1e-09 38.0 0.1 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain APO_RNA-bind PF05634.6 EPE32253.1 - 0.087 12.0 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 APO RNA-binding DUF4129 PF13559.1 EPE32256.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) NICE-3 PF07406.6 EPE32256.1 - 0.15 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 NICE-3 protein DDE_Tnp_1_6 PF13751.1 EPE32258.1 - 1.1 9.2 5.2 0.23 11.4 1.3 1.6 2 0 0 2 2 2 0 Transposase DDE domain DUF3431 PF11913.3 EPE32259.1 - 1.5e-25 90.0 0.0 2.3e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Fungal_trans_2 PF11951.3 EPE32260.1 - 7.5e-08 31.3 0.2 1.1e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE32260.1 - 7.9e-07 28.8 8.7 1.5e-06 27.9 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE32261.1 - 5.5e-21 74.6 24.4 5.5e-21 74.6 16.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE32261.1 - 5.5e-09 35.1 5.9 1.1e-08 34.0 4.1 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EPE32261.1 - 2.1e-05 23.1 6.9 2.1e-05 23.1 4.8 2.5 2 1 1 3 3 3 1 MFS/sugar transport protein MFS_3 PF05977.8 EPE32261.1 - 0.00019 19.7 3.8 0.0087 14.2 2.9 2.1 1 1 1 2 2 2 2 Transmembrane secretion effector HET PF06985.6 EPE32262.1 - 1.7e-23 83.2 0.0 4.8e-23 81.8 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) F-box PF00646.28 EPE32263.1 - 0.047 13.3 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 F-box domain LRR_8 PF13855.1 EPE32263.1 - 0.8 9.5 4.7 13 5.6 0.0 4.4 5 2 1 6 6 6 0 Leucine rich repeat FAD_binding_4 PF01565.18 EPE32265.1 - 4.4e-18 65.0 0.1 8.6e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE32265.1 - 0.0038 17.1 0.5 0.0094 15.8 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like Ank PF00023.25 EPE32266.1 - 4e-07 29.5 0.2 0.00065 19.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EPE32266.1 - 2.4e-06 27.8 0.0 5.1e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPE32266.1 - 3.9e-06 26.9 0.3 0.0036 17.5 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE32266.1 - 0.00014 22.2 0.1 0.014 15.9 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) RPAP3_C PF13877.1 EPE32266.1 - 0.046 13.6 0.2 2.2 8.2 0.1 2.6 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 H_lectin PF09458.5 EPE32267.1 - 1.5e-20 72.6 5.3 3.3e-15 55.5 0.0 4.4 5 0 0 5 5 5 3 H-type lectin domain Peptidase_M10 PF00413.19 EPE32267.1 - 9.9e-05 22.1 0.1 0.00023 20.8 0.1 1.6 1 0 0 1 1 1 1 Matrixin Peptidase_M7 PF02031.11 EPE32267.1 - 0.035 13.8 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family SAPS PF04499.10 EPE32268.1 - 6.9e-201 667.9 16.6 2.8e-200 665.9 5.5 3.7 3 1 0 3 3 3 2 SIT4 phosphatase-associated protein BPL_N PF09825.4 EPE32268.1 - 1.4 7.6 3.1 2.9 6.5 2.1 1.4 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Mso1_Sec1_bdg PF14475.1 EPE32268.1 - 1.9 7.9 4.4 0.69 9.3 0.3 2.4 2 0 0 2 2 2 0 Sec1-binding region of Mso1 Snf7 PF03357.16 EPE32269.1 - 9.6e-45 152.0 12.3 1.2e-44 151.7 8.5 1.0 1 0 0 1 1 1 1 Snf7 Reo_sigmaC PF04582.7 EPE32269.1 - 0.008 15.3 1.4 0.16 11.1 0.3 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EPE32269.1 - 0.0084 15.9 6.1 0.34 10.7 3.8 2.5 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 EPE32269.1 - 0.011 15.1 6.3 0.014 14.8 3.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 EPE32269.1 - 0.015 15.4 8.9 0.46 10.7 1.4 2.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1569 PF07606.6 EPE32269.1 - 0.021 14.7 2.3 0.05 13.5 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1569) Thioredoxin_3 PF13192.1 EPE32269.1 - 0.025 14.4 0.8 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Sec34 PF04136.10 EPE32269.1 - 0.029 14.0 2.5 0.049 13.3 1.1 1.7 2 0 0 2 2 2 0 Sec34-like family DUF3584 PF12128.3 EPE32269.1 - 0.031 11.6 6.0 0.04 11.2 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) OmpH PF03938.9 EPE32269.1 - 0.078 12.9 14.0 0.04 13.8 6.1 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF2205 PF10224.4 EPE32269.1 - 0.096 12.2 2.1 0.62 9.6 0.6 2.6 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Laminin_II PF06009.7 EPE32269.1 - 0.1 12.3 5.2 1.7 8.4 0.9 2.2 1 1 0 2 2 2 0 Laminin Domain II DUF848 PF05852.6 EPE32269.1 - 0.1 12.4 4.1 0.15 11.8 1.9 2.0 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4140 PF13600.1 EPE32269.1 - 0.17 12.3 4.2 0.28 11.6 0.0 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mod_r PF07200.8 EPE32269.1 - 0.19 11.6 6.4 0.13 12.2 3.0 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein COG2 PF06148.6 EPE32269.1 - 0.39 10.5 4.9 16 5.3 3.3 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Glutaredoxin PF00462.19 EPE32269.1 - 0.4 10.6 1.4 1 9.4 0.1 2.3 3 0 0 3 3 3 0 Glutaredoxin BLOC1_2 PF10046.4 EPE32269.1 - 0.5 10.5 6.6 2.5 8.2 2.5 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.15 EPE32269.1 - 0.67 9.7 0.0 0.67 9.7 0.0 3.3 3 1 0 3 3 2 0 Prefoldin subunit HET PF06985.6 EPE32270.1 - 2.3e-34 118.5 0.5 5.3e-34 117.3 0.4 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1771 PF08590.5 EPE32271.1 - 1.4e-23 82.6 6.0 1.4e-23 82.6 4.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EPE32271.1 - 2.7e-15 56.3 0.2 2.7e-15 56.3 0.1 1.9 2 0 0 2 2 2 1 Smr domain RHD PF00554.17 EPE32271.1 - 0.036 13.7 0.5 0.053 13.2 0.3 1.3 1 0 0 1 1 1 0 Rel homology domain (RHD) NIL PF09383.5 EPE32271.1 - 0.1 12.1 0.0 8.5 6.0 0.0 2.3 2 0 0 2 2 2 0 NIL domain H-K_ATPase_N PF09040.6 EPE32273.1 - 0.23 11.5 1.1 0.65 10.1 0.8 1.7 1 0 0 1 1 1 0 Gastric H+/K+-ATPase, N terminal domain DUF1996 PF09362.5 EPE32274.1 - 3.8e-66 223.1 0.1 5.4e-66 222.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EPE32274.1 - 1.7e-18 66.2 10.2 4.6e-18 64.9 7.1 1.8 1 0 0 1 1 1 1 WSC domain Oleosin PF01277.12 EPE32276.1 - 0.038 13.5 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Oleosin UCR_Fe-S_N PF10399.4 EPE32276.1 - 0.32 10.2 2.6 0.57 9.4 1.8 1.3 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal cobW PF02492.14 EPE32278.1 - 2.9e-40 137.5 0.1 4e-40 137.1 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EPE32278.1 - 0.001 18.8 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EPE32278.1 - 0.0021 17.8 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EPE32278.1 - 0.0047 16.8 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPE32278.1 - 0.0086 16.2 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EPE32278.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain Viral_helicase1 PF01443.13 EPE32278.1 - 0.029 13.9 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EPE32278.1 - 0.029 14.3 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EPE32278.1 - 0.039 13.4 0.2 0.57 9.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain CbiA PF01656.18 EPE32278.1 - 0.04 13.3 0.3 0.45 9.8 0.2 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 EPE32278.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EPE32278.1 - 0.086 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EPE32278.1 - 0.095 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase FAD_binding_4 PF01565.18 EPE32281.1 - 1.6e-23 82.7 3.1 3.1e-23 81.7 2.1 1.5 1 0 0 1 1 1 1 FAD binding domain AIB PF15334.1 EPE32281.1 - 0.039 13.0 0.1 0.061 12.3 0.1 1.2 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein Amidoligase_2 PF12224.3 EPE32282.1 - 1.6e-21 77.0 0.0 2.3e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Amidoligase_2 PF12224.3 EPE32283.1 - 1.2e-08 34.8 0.0 0.00014 21.5 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme Tyrosinase PF00264.15 EPE32284.1 - 1.7e-27 97.0 0.4 2.7e-27 96.3 0.3 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Dioxygenase_C PF00775.16 EPE32285.1 - 6.5e-12 45.0 0.3 3.5e-11 42.7 0.2 2.1 1 1 0 1 1 1 1 Dioxygenase Pkinase PF00069.20 EPE32286.1 - 7e-29 100.7 0.1 2.7e-28 98.8 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE32286.1 - 5.7e-07 28.8 0.4 1.5e-06 27.5 0.1 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase CTP_transf_1 PF01148.15 EPE32287.1 - 3.3e-06 26.9 20.2 3.4e-06 26.9 6.8 3.7 3 1 0 3 3 3 1 Cytidylyltransferase family Glyco_trans_2_3 PF13632.1 EPE32290.1 - 0.0024 17.6 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPE32290.1 - 0.056 13.2 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pkinase PF00069.20 EPE32291.1 - 8.3e-21 74.2 0.0 4.4e-20 71.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE32291.1 - 1.5e-06 27.5 0.0 0.009 15.1 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase CorA PF01544.13 EPE32292.1 - 1.8e-09 37.0 5.3 5.8e-09 35.4 3.7 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF63 PF01889.12 EPE32292.1 - 0.14 12.2 1.1 0.59 10.1 0.0 2.4 3 0 0 3 3 3 0 Membrane protein of unknown function DUF63 AA_permease PF00324.16 EPE32293.1 - 9.3e-43 146.2 35.8 1.6e-42 145.4 24.8 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE32293.1 - 2.8e-22 78.8 38.6 3.6e-22 78.4 26.7 1.1 1 0 0 1 1 1 1 Amino acid permease DIOX_N PF14226.1 EPE32294.1 - 1.6e-29 102.7 0.0 3.5e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPE32294.1 - 6.8e-23 80.8 0.0 1.2e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.2 EPE32295.1 - 5.7e-14 52.5 0.0 1e-13 51.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE32295.1 - 9.9e-07 28.6 0.0 6.3e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_3 PF13302.1 EPE32296.1 - 1.3e-22 80.5 0.0 1.6e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPE32296.1 - 6.2e-06 26.1 0.1 0.18 11.6 0.0 3.1 3 0 0 3 3 3 3 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE32296.1 - 0.0006 19.5 0.0 0.5 10.1 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_1 PF00583.19 EPE32296.1 - 0.028 14.4 0.0 12 5.9 0.0 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family Aminotran_1_2 PF00155.16 EPE32297.1 - 3.2e-34 118.4 0.0 3.7e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPE32297.1 - 0.052 12.6 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Sua5_yciO_yrdC PF01300.13 EPE32297.1 - 0.075 12.2 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 Telomere recombination V_ATPase_I PF01496.14 EPE32298.1 - 8.6e-302 1002.6 0.1 9.8e-302 1002.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 EPE32298.1 - 0.017 14.5 5.5 2.3 7.6 0.0 2.5 2 1 0 2 2 2 0 Intermediate filament protein Transposase_22 PF02994.9 EPE32298.1 - 0.035 12.6 0.4 0.059 11.8 0.1 1.4 2 0 0 2 2 2 0 L1 transposable element Baculo_PEP_C PF04513.7 EPE32298.1 - 0.045 13.5 1.7 4.2 7.2 0.1 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NDUF_B12 PF08122.7 EPE32298.1 - 0.07 12.8 0.3 0.24 11.1 0.2 2.0 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family DivIC PF04977.10 EPE32298.1 - 0.074 12.5 0.9 0.32 10.5 0.1 2.5 2 0 0 2 2 2 0 Septum formation initiator Reo_sigmaC PF04582.7 EPE32298.1 - 0.14 11.2 2.1 0.95 8.5 0.1 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 EPE32298.1 - 0.24 11.1 4.0 1.5 8.5 0.2 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF3552 PF12072.3 EPE32298.1 - 0.37 9.9 2.7 9.4 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) CENP-F_leu_zip PF10473.4 EPE32298.1 - 1.3 8.8 4.6 0.76 9.6 0.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EPE32298.1 - 5.9 6.4 6.6 2.5 7.6 1.6 2.2 2 0 0 2 2 2 0 IncA protein DUF2207 PF09972.4 EPE32299.1 - 0.069 11.7 0.8 0.098 11.2 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Uds1 PF15456.1 EPE32300.1 - 1.1e-44 151.4 6.2 1.1e-44 151.4 4.3 7.4 6 1 3 9 9 9 3 Up-regulated During Septation HR1 PF02185.11 EPE32300.1 - 0.0054 16.4 2.7 0.0054 16.4 1.9 8.3 6 3 4 10 10 10 4 Hr1 repeat DUF4634 PF15465.1 EPE32300.1 - 0.32 11.2 2.2 1.1 9.4 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4634) Peptidase_M41 PF01434.13 EPE32301.1 - 8e-71 237.8 0.5 1.3e-70 237.1 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EPE32301.1 - 1.1e-41 142.1 0.0 3e-41 140.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE32301.1 - 1.5e-05 25.0 0.3 0.00068 19.6 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EPE32301.1 - 3e-05 22.9 0.0 5.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EPE32301.1 - 3.1e-05 23.7 0.0 0.00013 21.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPE32301.1 - 4.7e-05 24.1 0.0 0.00014 22.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPE32301.1 - 5.5e-05 23.3 0.1 0.024 14.7 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPE32301.1 - 0.00032 20.5 0.6 0.0043 16.9 0.0 3.0 4 0 0 4 4 3 1 AAA domain RuvB_N PF05496.7 EPE32301.1 - 0.00059 18.9 0.0 0.0014 17.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EPE32301.1 - 0.0016 17.9 1.4 0.064 12.6 0.3 2.5 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPE32301.1 - 0.0026 16.8 1.5 0.022 13.8 0.2 2.3 1 1 1 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EPE32301.1 - 0.0028 17.3 1.9 0.0046 16.6 0.2 2.2 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 EPE32301.1 - 0.0028 17.0 0.2 0.0062 15.9 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EPE32301.1 - 0.0099 15.8 0.5 0.078 12.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EPE32301.1 - 0.017 14.2 0.2 0.039 13.0 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EPE32301.1 - 0.026 14.4 0.0 0.08 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EPE32301.1 - 0.045 12.6 0.0 0.081 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EPE32301.1 - 0.071 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPE32301.1 - 0.099 12.2 0.2 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 EPE32301.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.1 EPE32302.1 - 8.3e-21 73.1 26.3 5.5e-08 32.7 0.4 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EPE32302.1 - 1.4e-19 69.1 31.1 1.8e-05 24.8 1.3 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE32302.1 - 3.5e-10 39.4 26.9 0.0013 18.8 1.2 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPE32302.1 - 0.00023 21.1 4.7 2.1 8.5 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EPE32302.1 - 0.012 15.9 15.2 0.031 14.6 1.6 3.6 1 1 2 3 3 3 0 TRAF-type zinc finger zf-met PF12874.2 EPE32302.1 - 0.084 13.1 11.3 0.18 12.0 0.5 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 EPE32302.1 - 0.3 10.7 4.1 2.4 7.8 0.1 3.1 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger CHORD PF04968.7 EPE32302.1 - 3.1 8.0 16.0 3.8 7.8 0.2 4.5 1 1 3 4 4 4 0 CHORD Aldedh PF00171.17 EPE32303.1 - 3.5e-25 88.2 0.0 4.8e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NTP_transf_2 PF01909.18 EPE32303.1 - 2.1e-07 31.1 0.0 6e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain PTA_PTB PF01515.14 EPE32303.1 - 0.0015 17.6 0.1 0.0039 16.3 0.0 1.6 2 0 0 2 2 2 1 Phosphate acetyl/butaryl transferase GMC_oxred_N PF00732.14 EPE32304.1 - 1.7e-57 194.8 0.0 2.2e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE32304.1 - 5.7e-38 130.4 0.0 8.9e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPE32304.1 - 8.5e-06 24.8 0.0 1.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE32304.1 - 0.00015 20.7 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPE32304.1 - 0.00024 21.0 0.0 0.00054 19.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE32304.1 - 0.0011 17.9 0.0 0.0043 15.9 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EPE32304.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE32304.1 - 0.078 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE32304.1 - 0.13 10.7 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GDI PF00996.13 EPE32304.1 - 0.15 10.3 0.0 0.23 9.7 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Scytalone_dh PF02982.9 EPE32305.1 - 1.8e-76 255.1 0.7 2.3e-76 254.7 0.5 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EPE32305.1 - 8.1e-08 32.2 0.4 1.1e-07 31.8 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain Zn_clus PF00172.13 EPE32306.1 - 6.4e-06 25.9 9.9 1.2e-05 25.0 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L38e PF01781.13 EPE32308.1 - 1.9e-32 110.7 1.3 2.3e-32 110.5 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family LAGLIDADG_WhiA PF14527.1 EPE32308.1 - 0.1 12.4 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain SAP PF02037.22 EPE32309.1 - 4e-05 23.0 0.0 5.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 SAP domain Ish1 PF10281.4 EPE32309.1 - 0.00017 21.5 0.2 0.00026 20.9 0.1 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EPE32309.1 - 0.00035 20.0 0.0 0.00053 19.4 0.0 1.3 1 0 0 1 1 1 1 HeH/LEM domain Mtr2 PF10429.4 EPE32311.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.7 1 1 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Mesd PF10185.4 EPE32311.1 - 0.03 13.9 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor NTF2 PF02136.15 EPE32311.1 - 0.12 12.7 0.1 0.3 11.4 0.0 1.6 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain tRNA-synt_1g PF09334.6 EPE32312.1 - 1.2e-121 406.0 0.1 2e-121 405.3 0.1 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EPE32312.1 - 3.9e-27 94.5 2.9 3.3e-11 41.9 0.0 4.0 1 1 3 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EPE32312.1 - 7.2e-08 31.8 0.0 0.00015 20.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Peptidase_M48 PF01435.13 EPE32314.1 - 1.3e-46 159.0 0.0 2.1e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EPE32314.1 - 0.056 12.4 0.0 0.12 11.3 0.0 1.6 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF955 PF06114.8 EPE32314.1 - 0.12 12.1 0.2 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF955) DUF2201_N PF13203.1 EPE32314.1 - 0.21 10.7 0.5 0.38 9.8 0.1 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain RNA_polI_A14 PF08203.6 EPE32315.1 - 0.001 19.2 0.1 0.0033 17.6 0.0 1.9 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 RNase_H2-Ydr279 PF09468.5 EPE32315.1 - 7.5 5.6 7.5 10 5.2 5.2 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Ku_N PF03731.10 EPE32316.1 - 0.024 14.0 0.3 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain CENP-B_dimeris PF09026.5 EPE32316.1 - 2.8 8.2 6.1 44 4.3 2.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NMO PF03060.10 EPE32317.1 - 8.8e-71 238.7 0.9 1e-70 238.5 0.6 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EPE32317.1 - 3.3e-05 22.9 0.0 0.0016 17.4 0.0 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EPE32317.1 - 0.0018 17.1 4.1 0.0029 16.5 2.8 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Taxilin PF09728.4 EPE32319.1 - 5.8e-89 298.2 54.6 8.3e-89 297.7 37.9 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.3 EPE32319.1 - 0.63 9.7 50.7 0.22 11.2 2.8 4.6 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 EPE32319.1 - 6.7 5.7 6.8 2.7 7.0 0.4 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein M16C_assoc PF08367.6 EPE32320.1 - 7.5e-59 198.5 0.0 1.1e-58 198.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EPE32320.1 - 6.3e-36 123.7 0.0 1.1e-18 67.5 0.0 3.5 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPE32320.1 - 1.2e-05 25.0 0.0 0.00024 20.8 0.0 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Exonuc_VII_L PF02601.10 EPE32320.1 - 0.15 11.2 0.1 0.29 10.3 0.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Acetyltransf_3 PF13302.1 EPE32321.1 - 2.9e-13 50.1 0.7 2e-12 47.4 0.5 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE32321.1 - 0.002 18.1 0.1 0.0041 17.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family HET PF06985.6 EPE32322.1 - 9.3e-23 80.9 0.0 3.1e-22 79.2 0.0 1.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) zf-C2H2_2 PF12756.2 EPE32325.1 - 6.5e-27 93.5 14.6 1.5e-24 85.9 1.1 3.3 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EPE32325.1 - 0.00037 20.5 20.3 0.001 19.1 2.2 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding E2R135 PF11570.3 EPE32326.1 - 0.19 11.7 2.4 45 4.1 0.2 3.4 2 1 1 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 Trypan_glycop PF00913.14 EPE32328.1 - 0.079 11.8 1.4 0.2 10.5 1.1 1.6 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) DNA_pol_E_B PF04042.11 EPE32330.1 - 8.8e-50 168.8 0.0 1.2e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Elong-fact-P_C PF09285.6 EPE32330.1 - 0.38 10.1 2.0 0.62 9.4 0.0 2.3 3 0 0 3 3 3 0 Elongation factor P, C-terminal Sporozoite_P67 PF05642.6 EPE32331.1 - 0.93 7.2 11.1 1 7.1 7.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Aa_trans PF01490.13 EPE32332.1 - 9.4e-87 291.1 33.9 1.1e-86 290.8 23.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MAGE PF01454.14 EPE32332.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 MAGE family AA_permease PF00324.16 EPE32333.1 - 2.2e-55 187.8 34.1 2.9e-55 187.4 23.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE32333.1 - 4.9e-18 64.8 39.5 8.1e-18 64.1 27.4 1.2 1 0 0 1 1 1 1 Amino acid permease NMO PF03060.10 EPE32334.1 - 1.8e-37 129.2 3.0 1.6e-29 103.0 1.5 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EPE32334.1 - 1.3e-06 27.4 2.8 1.9e-06 26.9 2.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EPE32334.1 - 5.9e-05 22.1 0.0 0.021 13.7 0.3 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EPE32334.1 - 0.00083 18.3 0.3 0.0013 17.7 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase RNA_pol_L_2 PF13656.1 EPE32335.1 - 2.2e-21 75.0 0.0 2.8e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EPE32335.1 - 8.7e-13 47.1 0.0 1.2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2436 PF10365.4 EPE32335.1 - 0.15 11.7 0.0 0.49 10.0 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2436) adh_short PF00106.20 EPE32336.1 - 1.8e-21 76.7 0.2 2.5e-21 76.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE32336.1 - 3.3e-14 53.2 0.6 4.1e-14 52.9 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EPE32336.1 - 2.7e-07 30.0 0.0 8.1e-07 28.4 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EPE32336.1 - 4.2e-05 23.2 0.2 7.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EPE32336.1 - 0.0002 20.7 0.0 0.00088 18.5 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EPE32336.1 - 0.00047 20.2 0.0 0.0013 18.8 0.0 1.8 3 0 0 3 3 3 1 NADH(P)-binding NAD_binding_2 PF03446.10 EPE32336.1 - 0.0017 18.2 0.1 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.10 EPE32336.1 - 0.019 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.12 EPE32336.1 - 0.073 11.9 0.0 0.22 10.3 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain ApbA PF02558.11 EPE32336.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EPE32336.1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Orn_Arg_deC_N PF02784.11 EPE32337.1 - 2.7e-77 259.3 0.0 3.5e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EPE32337.1 - 6.4e-30 103.2 0.1 1.2e-29 102.3 0.1 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DNA_pol_A_exo1 PF01612.15 EPE32338.1 - 3.2e-16 59.3 0.0 4.9e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.17 EPE32339.1 - 3e-20 71.5 0.2 3.3e-20 71.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain DUF2069 PF09842.4 EPE32341.1 - 0.063 13.2 1.1 0.13 12.2 0.8 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2069) DOPA_dioxygen PF08883.6 EPE32342.1 - 2.3e-31 107.9 0.0 3.9e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Zn_clus PF00172.13 EPE32343.1 - 2.9e-07 30.2 7.8 5.3e-07 29.4 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE32343.1 - 1.1e-05 24.2 0.4 2.1e-05 23.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CK_II_beta PF01214.13 EPE32344.1 - 1.9e-77 258.9 0.0 3.2e-77 258.1 0.0 1.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EPE32344.1 - 0.0012 19.4 7.7 0.0012 19.4 5.3 1.9 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.6 EPE32344.1 - 0.26 9.3 2.1 0.33 9.0 1.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nucleoplasmin PF03066.10 EPE32344.1 - 0.32 10.5 7.2 0.57 9.6 5.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EPE32344.1 - 0.41 8.6 2.8 0.52 8.2 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_3 PF00933.16 EPE32345.1 - 2.6e-90 302.4 0.0 3.8e-90 301.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE32345.1 - 2.7e-60 203.7 1.2 1.5e-58 197.9 0.0 2.7 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE32345.1 - 1e-22 79.8 0.0 2.5e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3667 PF12412.3 EPE32345.1 - 0.1 11.9 0.1 0.27 10.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) Methyltransf_23 PF13489.1 EPE32348.1 - 8.8e-18 64.5 0.0 1.4e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE32348.1 - 0.0019 18.5 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE32348.1 - 0.0034 17.8 0.0 0.0066 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE32348.1 - 0.0047 17.3 0.0 0.047 14.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE32348.1 - 0.0061 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_C48 PF02902.14 EPE32349.1 - 3.6e-07 30.0 0.3 5.9e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Zn_clus PF00172.13 EPE32351.1 - 0.012 15.5 1.7 0.033 14.1 1.2 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_47 PF01532.15 EPE32352.1 - 5.3e-133 443.9 0.0 6.1e-133 443.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ETF_QO PF05187.8 EPE32353.1 - 5.8e-43 145.3 0.0 1e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EPE32353.1 - 1.7e-08 33.7 0.0 0.00015 20.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE32353.1 - 2.4e-08 33.8 0.0 7e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPE32353.1 - 1.2e-06 27.8 0.0 0.0013 17.8 0.1 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 EPE32353.1 - 4.8e-06 25.6 1.3 0.0022 16.9 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EPE32353.1 - 7.3e-05 22.7 0.3 0.00015 21.6 0.1 1.7 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE32353.1 - 0.00022 19.8 0.6 0.00033 19.2 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 EPE32353.1 - 0.00048 19.9 0.3 0.0015 18.2 0.2 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EPE32353.1 - 0.00055 19.1 0.1 0.00085 18.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EPE32353.1 - 0.00058 18.6 0.2 0.17 10.4 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EPE32353.1 - 0.00063 18.8 0.3 0.00092 18.3 0.2 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EPE32353.1 - 0.002 18.1 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 EPE32353.1 - 0.0073 16.6 0.9 0.022 15.1 0.6 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.22 EPE32353.1 - 0.011 16.0 0.4 5.1 7.5 0.3 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE32353.1 - 0.03 13.2 0.2 0.046 12.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.19 EPE32353.1 - 0.083 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.17 EPE32353.1 - 0.16 10.7 0.4 0.25 10.1 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Macoilin PF09726.4 EPE32354.1 - 0.94 7.6 22.6 1.2 7.2 15.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Glycos_transf_1 PF00534.15 EPE32355.1 - 2.1e-09 37.0 0.0 4.8e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF3492 PF11997.3 EPE32355.1 - 3.8e-07 29.9 0.0 2.6e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 EPE32355.1 - 0.00054 20.1 0.0 0.0019 18.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EPE32355.1 - 0.038 14.2 0.0 0.3 11.3 0.0 2.4 1 1 0 1 1 1 0 Glycosyl transferases group 1 Polysacc_deac_1 PF01522.16 EPE32356.1 - 0.029 14.0 0.1 0.07 12.7 0.0 1.7 1 0 0 1 1 1 0 Polysaccharide deacetylase Epimerase PF01370.16 EPE32357.1 - 1.1e-31 110.1 0.0 6e-31 107.6 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EPE32357.1 - 2.4e-18 65.8 0.2 5.2e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NAD_binding_4 PF07993.7 EPE32357.1 - 3.7e-07 29.3 0.0 2.8e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EPE32357.1 - 5.2e-07 28.8 0.0 0.0015 17.5 0.0 3.8 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPE32357.1 - 2.3e-06 26.5 0.0 0.0024 16.6 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family DAO PF01266.19 EPE32357.1 - 0.00013 20.9 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase adh_short PF00106.20 EPE32357.1 - 0.00024 21.0 0.0 0.00097 19.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE32357.1 - 0.0044 16.7 0.0 0.014 15.0 0.0 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_8 PF13450.1 EPE32357.1 - 0.0059 16.6 0.0 0.021 14.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NmrA PF05368.8 EPE32357.1 - 0.016 14.4 0.2 0.093 11.9 0.0 2.2 3 0 0 3 3 3 0 NmrA-like family 3HCDH_N PF02737.13 EPE32357.1 - 0.03 13.9 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EPE32357.1 - 0.039 12.8 0.0 0.69 8.7 0.0 2.7 1 1 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPE32357.1 - 0.049 13.6 0.1 0.67 9.9 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding TPMT PF05724.6 EPE32357.1 - 0.055 12.8 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) UDPG_MGDP_dh_N PF03721.9 EPE32357.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 EPE32357.1 - 0.13 11.1 0.0 0.26 10.2 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase DUF2014 PF09427.5 EPE32359.1 - 1.1e-102 342.6 0.0 1.8e-102 341.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EPE32359.1 - 4.3e-17 61.5 0.5 8.3e-17 60.6 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3255 PF11631.3 EPE32359.1 - 0.043 13.4 0.1 0.25 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3255) NIR_SIR PF01077.17 EPE32360.1 - 3.2e-30 104.5 0.0 5.5e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 EPE32360.1 - 9.5e-29 100.7 0.2 1.7e-28 99.8 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE32360.1 - 3.3e-16 59.4 6.1 5.9e-15 55.4 1.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EPE32360.1 - 4.3e-16 58.5 0.0 1.1e-15 57.1 0.0 1.8 2 0 0 2 2 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 EPE32360.1 - 1.4e-13 50.6 3.7 2.1e-11 43.7 2.7 2.6 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske PF00355.21 EPE32360.1 - 9.3e-11 41.1 0.1 3.4e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 EPE32360.1 - 2.1e-09 36.8 0.0 6.3e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 EPE32360.1 - 1.8e-08 34.7 0.0 0.0002 21.4 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE32360.1 - 3.8e-06 26.0 0.1 0.023 13.6 0.0 4.0 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPE32360.1 - 0.002 17.9 0.2 4.5 7.0 0.0 3.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EPE32360.1 - 0.021 13.8 0.0 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 EPE32360.1 - 0.026 13.4 0.0 0.11 11.3 0.0 1.9 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 EPE32360.1 - 0.041 13.8 0.6 3.1 7.8 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain Bac_rhodopsin PF01036.13 EPE32361.1 - 6.9e-34 117.0 19.1 8.8e-34 116.7 13.2 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Frag1 PF10277.4 EPE32361.1 - 0.0052 16.2 8.4 0.0052 16.2 5.8 1.9 1 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Prefoldin PF02996.12 EPE32363.1 - 2.4e-26 91.7 0.1 3.2e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EPE32363.1 - 0.0032 17.2 2.0 0.45 10.3 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit Cep57_MT_bd PF06657.8 EPE32363.1 - 0.018 14.9 2.0 0.055 13.4 0.1 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Prefoldin_3 PF13758.1 EPE32363.1 - 0.03 14.0 0.0 0.086 12.6 0.0 1.8 1 1 0 1 1 1 0 Prefoldin subunit Phage-MuB_C PF09077.6 EPE32363.1 - 0.089 12.4 0.2 0.26 10.9 0.1 1.8 2 0 0 2 2 2 0 Mu B transposition protein, C terminal IncA PF04156.9 EPE32363.1 - 0.17 11.4 1.9 2.8 7.5 0.2 2.0 2 0 0 2 2 2 0 IncA protein AAA PF00004.24 EPE32364.1 - 1.5e-14 54.3 0.0 3.5e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE32364.1 - 2.6e-10 40.5 0.0 1.3e-09 38.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE32364.1 - 2.1e-09 37.6 0.0 2.7e-08 34.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EPE32364.1 - 5.8e-05 23.9 0.0 0.0012 19.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EPE32364.1 - 0.00045 19.9 0.1 0.0016 18.1 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EPE32364.1 - 0.0038 17.1 1.0 0.021 14.8 0.0 2.5 3 0 0 3 3 2 1 AAA domain DUF2075 PF09848.4 EPE32364.1 - 0.004 16.1 0.0 0.012 14.6 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EPE32364.1 - 0.0057 16.9 0.1 0.06 13.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EPE32364.1 - 0.0063 16.1 0.6 0.023 14.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EPE32364.1 - 0.0082 15.8 0.0 0.11 12.2 0.0 2.6 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EPE32364.1 - 0.0087 15.7 0.0 0.026 14.1 0.0 1.8 1 1 0 1 1 1 1 NACHT domain BAH PF01426.13 EPE32364.1 - 0.011 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 BAH domain AAA_32 PF13654.1 EPE32364.1 - 0.023 13.3 0.0 0.044 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EPE32364.1 - 0.041 13.4 0.1 0.94 9.0 0.0 3.0 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EPE32364.1 - 0.047 13.3 0.3 0.41 10.3 0.0 2.3 2 0 0 2 2 2 0 NTPase PIF1 PF05970.9 EPE32364.1 - 0.064 12.1 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.17 EPE32364.1 - 0.068 13.3 0.1 0.5 10.5 0.0 2.6 3 0 0 3 3 2 0 RNA helicase WD40 PF00400.27 EPE32365.1 - 4.5e-52 172.1 11.9 2.3e-09 36.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 EPE32365.1 - 0.0047 16.4 0.2 4.7 6.5 0.0 2.6 2 1 0 2 2 2 2 PQQ-like domain Nup160 PF11715.3 EPE32365.1 - 0.0077 14.4 6.5 8.5 4.3 0.1 4.7 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Ank_2 PF12796.2 EPE32366.1 - 4.1e-33 113.5 0.5 8.5e-14 51.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPE32366.1 - 2.7e-32 110.0 1.0 1.8e-08 34.3 0.0 4.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EPE32366.1 - 1.4e-26 90.8 4.1 5e-07 29.2 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EPE32366.1 - 8.3e-25 86.7 10.5 7.5e-06 26.3 0.0 5.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE32366.1 - 2.6e-19 67.3 0.8 0.0012 18.8 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Shal-type PF11601.3 EPE32366.1 - 0.18 11.3 1.0 0.44 10.1 0.1 2.0 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels TMF_TATA_bd PF12325.3 EPE32367.1 - 3.3e-39 133.3 9.7 3.3e-39 133.3 6.7 7.1 3 2 4 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EPE32367.1 - 5.4e-18 64.5 18.6 5.4e-18 64.5 12.9 8.1 4 3 2 7 7 7 3 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 EPE32367.1 - 0.57 10.1 24.6 0.43 10.5 2.7 4.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Ceramidase PF05875.7 EPE32368.1 - 3.5e-106 354.1 10.0 4.8e-106 353.7 6.9 1.2 1 0 0 1 1 1 1 Ceramidase Renin_r PF07850.9 EPE32368.1 - 0.087 13.1 0.1 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 Renin receptor-like protein Prefoldin_2 PF01920.15 EPE32369.1 - 5e-20 71.2 4.1 6.2e-20 70.9 2.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF2570 PF10828.3 EPE32369.1 - 0.024 14.2 2.5 0.68 9.5 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Lge1 PF11488.3 EPE32369.1 - 0.032 14.4 2.3 2.1 8.6 1.1 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 USP8_interact PF08941.5 EPE32369.1 - 0.034 13.4 1.7 0.037 13.3 0.1 1.7 2 0 0 2 2 2 0 USP8 interacting DUF972 PF06156.8 EPE32369.1 - 0.035 14.4 3.7 4.2 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Rootletin PF15035.1 EPE32369.1 - 0.036 14.0 4.3 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion TBPIP PF07106.8 EPE32369.1 - 0.052 13.0 4.9 0.29 10.6 0.1 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RasGAP_C PF03836.10 EPE32369.1 - 0.054 13.1 0.1 0.054 13.1 0.1 2.2 2 1 0 2 2 2 0 RasGAP C-terminus CASP_C PF08172.7 EPE32369.1 - 0.077 12.0 3.4 0.31 10.0 0.1 2.0 2 0 0 2 2 2 0 CASP C terminal CENP-F_leu_zip PF10473.4 EPE32369.1 - 0.082 12.7 6.8 0.33 10.7 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlqD PF11068.3 EPE32369.1 - 0.088 12.8 5.3 0.29 11.1 0.9 2.0 2 0 0 2 2 2 0 YlqD protein AAA_27 PF13514.1 EPE32369.1 - 0.094 10.3 0.9 0.13 9.9 0.6 1.2 1 0 0 1 1 1 0 AAA domain FH2 PF02181.18 EPE32369.1 - 0.12 11.2 1.2 1.7 7.4 0.0 2.0 2 0 0 2 2 2 0 Formin Homology 2 Domain FlxA PF14282.1 EPE32369.1 - 0.13 12.2 12.9 0.24 11.3 4.9 2.1 2 0 0 2 2 2 0 FlxA-like protein Jnk-SapK_ap_N PF09744.4 EPE32369.1 - 0.13 12.2 3.7 0.55 10.2 0.1 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 ADIP PF11559.3 EPE32369.1 - 0.19 11.6 9.8 2 8.2 2.7 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2681 PF10883.3 EPE32369.1 - 0.19 11.9 8.3 5.8 7.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SF-assemblin PF06705.6 EPE32369.1 - 0.19 10.8 2.6 0.64 9.1 0.0 2.0 2 0 0 2 2 2 0 SF-assemblin/beta giardin Prefoldin PF02996.12 EPE32369.1 - 0.21 11.2 8.5 1.6 8.3 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit PspA_IM30 PF04012.7 EPE32369.1 - 0.22 10.8 10.7 1.6 8.0 0.1 2.0 2 0 0 2 2 2 0 PspA/IM30 family Striatin PF08232.7 EPE32369.1 - 0.23 11.7 4.7 3.2 8.0 0.3 2.0 2 0 0 2 2 2 0 Striatin family THOC7 PF05615.8 EPE32369.1 - 0.27 11.5 7.1 1.6 8.9 0.2 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 Spc24 PF08286.6 EPE32369.1 - 0.27 10.9 4.4 3.5 7.3 0.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.6 EPE32369.1 - 0.3 9.7 4.1 2.3 6.8 0.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 EPE32369.1 - 0.33 10.7 8.0 3.4 7.4 0.1 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 EPE32369.1 - 0.34 10.7 3.6 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RmuC PF02646.11 EPE32369.1 - 0.36 9.6 4.4 1.1 8.0 0.0 2.0 2 0 0 2 2 2 0 RmuC family Cast PF10174.4 EPE32369.1 - 0.37 8.7 6.2 0.62 8.0 0.1 2.0 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Seryl_tRNA_N PF02403.17 EPE32369.1 - 0.37 10.8 5.2 0.49 10.4 0.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.4 EPE32369.1 - 0.38 10.9 3.8 0.48 10.5 0.1 2.2 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 EPE32369.1 - 0.39 10.8 8.2 2.6 8.1 0.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4047 PF13256.1 EPE32369.1 - 0.4 10.6 3.8 0.83 9.6 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF3450 PF11932.3 EPE32369.1 - 0.41 9.8 9.6 1.8 7.7 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 EPE32369.1 - 0.48 9.3 5.1 8.3 5.2 0.0 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FliD_C PF07195.7 EPE32369.1 - 0.49 9.6 4.3 8.7 5.5 1.1 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Phage_GP20 PF06810.6 EPE32369.1 - 0.49 9.8 4.7 1.2 8.5 0.2 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 HALZ PF02183.13 EPE32369.1 - 0.5 10.1 4.2 1 9.1 0.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper OmpH PF03938.9 EPE32369.1 - 0.56 10.1 8.0 6.6 6.6 0.1 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4618 PF15397.1 EPE32369.1 - 0.77 9.0 7.2 1.2 8.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Bap31 PF05529.7 EPE32369.1 - 0.87 9.0 4.9 9.8 5.5 0.1 2.0 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF4200 PF13863.1 EPE32369.1 - 0.91 9.4 8.0 1.3 8.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.2 EPE32369.1 - 1.1 9.0 6.9 1.6 8.5 0.4 2.1 2 0 0 2 2 2 0 Tropomyosin like CtIP_N PF10482.4 EPE32369.1 - 1.3 8.8 4.7 0.87 9.3 1.1 1.9 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain FlaC_arch PF05377.6 EPE32369.1 - 1.3 8.9 5.1 0.82 9.6 0.1 2.6 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Tektin PF03148.9 EPE32369.1 - 1.4 7.3 6.7 2.5 6.5 0.1 2.0 2 0 0 2 2 2 0 Tektin family SlyX PF04102.7 EPE32369.1 - 1.6 9.1 9.1 1.6 9.1 2.9 2.1 2 0 0 2 2 2 0 SlyX IncA PF04156.9 EPE32369.1 - 2.7 7.5 9.4 17 4.9 6.5 1.9 1 1 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 EPE32369.1 - 4 7.1 9.1 7.9 6.2 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1640 PF07798.6 EPE32369.1 - 4.5 7.2 8.5 25 4.8 5.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Cep57_CLD_2 PF14197.1 EPE32369.1 - 4.9 7.1 6.4 0.82 9.6 0.2 2.3 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Microtub_assoc PF07989.6 EPE32369.1 - 8.3 6.3 7.2 1.5 8.6 0.4 2.4 2 1 0 2 2 2 0 Microtubule associated TMF_DNA_bd PF12329.3 EPE32369.1 - 8.5 6.2 11.3 0.54 10.1 0.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mito_carr PF00153.22 EPE32371.1 - 1.9e-53 178.1 1.9 2e-19 69.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CN_hydrolase PF00795.17 EPE32372.1 - 7e-25 87.4 0.0 1.2e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PEMT PF04191.8 EPE32373.1 - 2.4e-30 104.7 3.1 4.2e-30 103.9 2.2 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase RXT2_N PF08595.6 EPE32374.1 - 9.7e-43 145.5 2.0 4.9e-42 143.2 0.0 2.4 2 0 0 2 2 2 1 RXT2-like, N-terminal Homoserine_dh PF00742.14 EPE32375.1 - 2.7e-49 167.2 0.0 5.1e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EPE32375.1 - 5.2e-18 65.5 0.0 8.6e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain IGPS PF00218.16 EPE32375.1 - 0.012 14.6 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Methyltransf_4 PF02390.12 EPE32377.1 - 1.4e-54 184.2 0.0 1.9e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EPE32377.1 - 0.00042 20.8 0.0 0.00078 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE32377.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EPE32377.1 - 0.0026 16.7 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_25 PF13649.1 EPE32377.1 - 0.0036 17.6 0.0 0.0085 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE32377.1 - 0.0037 17.7 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE32377.1 - 0.014 14.8 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 EPE32377.1 - 0.022 13.8 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Psb28 PF03912.9 EPE32377.1 - 0.031 14.2 0.0 3.8 7.5 0.1 2.4 2 0 0 2 2 2 0 Psb28 protein Methyltransf_32 PF13679.1 EPE32377.1 - 0.035 13.8 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EPE32377.1 - 0.039 13.5 0.0 0.082 12.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EPE32377.1 - 0.061 13.8 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DUF4191 PF13829.1 EPE32377.1 - 0.067 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) PXA PF02194.10 EPE32378.1 - 1.5e-47 161.5 0.2 1.5e-47 161.5 0.1 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EPE32378.1 - 5.3e-29 100.5 0.3 1.7e-28 98.9 0.0 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EPE32378.1 - 5e-21 74.5 0.7 1.4e-20 73.1 0.5 1.8 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EPE32378.1 - 3.8e-09 36.6 0.2 1.6e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain Viral_P18 PF04521.8 EPE32378.1 - 0.21 11.0 1.3 0.57 9.6 0.9 1.7 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Lge1 PF11488.3 EPE32378.1 - 5.4 7.2 7.6 7.6 6.8 0.1 3.5 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 ESCRT-II PF05871.7 EPE32379.1 - 8.1e-51 171.5 1.2 1e-50 171.2 0.8 1.0 1 0 0 1 1 1 1 ESCRT-II complex subunit BRCT PF00533.21 EPE32380.1 - 2.7e-37 126.7 0.1 2.9e-10 40.1 0.0 6.3 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPE32380.1 - 2.6e-30 104.0 1.9 3.1e-20 71.7 0.1 5.1 6 0 0 6 6 6 3 twin BRCT domain Abhydrolase_6 PF12697.2 EPE32381.1 - 5.8e-25 88.5 0.0 8.6e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE32381.1 - 1e-05 25.2 0.0 9e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE32381.1 - 0.00033 20.4 0.0 0.00063 19.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EPE32381.1 - 0.092 11.2 0.0 0.17 10.3 0.0 1.3 1 0 0 1 1 1 0 Ndr family Gryzun PF07919.7 EPE32382.1 - 5.6e-105 351.7 0.0 9.6e-105 350.9 0.0 1.3 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EPE32382.1 - 1.3e-75 254.0 0.2 3.3e-68 229.8 0.8 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EPE32382.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking DUF4078 PF13300.1 EPE32383.1 - 3.1e-28 97.6 17.5 3.1e-28 97.6 12.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) DUF903 PF06004.7 EPE32383.1 - 0.14 11.7 1.3 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) Asp PF00026.18 EPE32386.1 - 3.2e-11 43.0 0.0 4.8e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EPE32386.1 - 0.045 13.3 0.0 0.12 11.9 0.0 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EPE32386.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal ADH_N PF08240.7 EPE32390.1 - 1.6e-26 92.2 0.7 3.4e-26 91.1 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE32390.1 - 1.5e-15 56.8 1.5 6e-15 54.9 1.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE32390.1 - 0.00054 20.8 0.4 0.00099 20.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Protoglobin PF11563.3 EPE32391.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Protoglobin Sigma70_ner PF04546.8 EPE32391.1 - 2.4 7.6 7.9 7.2 6.1 5.0 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Myosin_HC-like PF07058.6 EPE32391.1 - 2.7 7.0 6.2 6.7 5.6 0.2 2.2 2 0 0 2 2 2 0 Myosin II heavy chain-like CENP-B_dimeris PF09026.5 EPE32391.1 - 3.1 8.0 10.0 7.4 6.8 6.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain APH PF01636.18 EPE32392.1 - 3.3e-10 40.1 0.0 5.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE32392.1 - 0.042 13.4 0.1 0.07 12.6 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase ADH_zinc_N PF00107.21 EPE32393.1 - 8.3e-24 83.5 1.0 2e-23 82.3 0.7 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE32393.1 - 6.5e-22 77.3 4.6 1.5e-21 76.2 3.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPE32393.1 - 5.5e-05 24.0 0.5 0.00011 23.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EPE32393.1 - 0.013 16.0 0.1 0.023 15.2 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 EPE32393.1 - 0.051 13.1 1.0 0.086 12.4 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain His_Phos_2 PF00328.17 EPE32394.1 - 2e-37 129.3 0.0 2.4e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sel1 PF08238.7 EPE32395.1 - 7e-31 105.9 28.4 7.5e-06 26.4 0.6 7.9 8 0 0 8 8 8 7 Sel1 repeat Chitin_synth_2 PF03142.10 EPE32396.1 - 2.9e-291 966.4 0.6 3.7e-291 966.1 0.0 1.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EPE32396.1 - 7.2e-19 68.2 2.1 2.8e-18 66.3 1.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPE32396.1 - 8.1e-15 55.2 0.0 2.2e-13 50.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EPE32396.1 - 1e-13 50.8 0.3 2.6e-10 39.9 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EPE32396.1 - 0.00016 21.0 0.0 0.0027 17.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF639 PF04842.7 EPE32396.1 - 0.024 12.8 0.0 0.034 12.3 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Glycos_transf_2 PF00535.21 EPE32396.1 - 0.098 12.3 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 Pkinase PF00069.20 EPE32397.1 - 6.1e-70 235.3 0.0 1e-69 234.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE32397.1 - 2.9e-39 134.7 0.0 4.8e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE32397.1 - 1.9e-10 40.1 0.0 5.6e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like POLO_box PF00659.13 EPE32397.1 - 4.5e-10 39.3 0.2 8.6e-05 22.4 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 EPE32397.1 - 0.0012 17.9 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 EPE32398.1 - 1.7e-42 144.3 0.3 1.7e-42 144.3 0.2 1.9 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) HOOK PF05622.7 EPE32398.1 - 0.00082 17.3 4.0 0.00082 17.3 2.8 1.6 2 0 0 2 2 2 1 HOOK protein FUN14 PF04930.10 EPE32398.1 - 0.078 13.2 0.2 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 FUN14 family IncA PF04156.9 EPE32398.1 - 0.22 11.0 4.0 0.06 12.9 0.4 1.7 2 0 0 2 2 2 0 IncA protein Fmp27_WPPW PF10359.4 EPE32398.1 - 0.39 9.0 5.3 2.5 6.3 2.1 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Osmo_CC PF08946.5 EPE32398.1 - 0.48 10.4 5.5 3.3 7.8 0.1 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil RNase_H2-Ydr279 PF09468.5 EPE32398.1 - 0.69 9.0 7.2 0.26 10.4 0.3 2.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Striatin PF08232.7 EPE32398.1 - 1.2 9.4 12.0 0.47 10.7 2.8 2.1 2 0 0 2 2 2 0 Striatin family MerR-DNA-bind PF09278.6 EPE32398.1 - 6.5 7.2 10.9 0.11 12.8 1.1 2.5 2 1 1 3 3 3 0 MerR, DNA binding SBDS PF01172.13 EPE32400.1 - 1.2e-25 89.0 1.3 1.4e-25 88.8 0.9 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NmrA PF05368.8 EPE32401.1 - 6.8e-62 208.7 0.0 8.3e-62 208.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE32401.1 - 1.2e-13 51.4 0.0 1.9e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE32401.1 - 5.5e-06 25.2 0.0 9.1e-06 24.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EPE32401.1 - 0.0083 15.1 0.2 0.026 13.4 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase Peroxin-13_N PF04088.8 EPE32402.1 - 4e-60 202.3 0.0 6.5e-60 201.6 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 EPE32402.1 - 2.2e-07 30.1 0.0 4.5e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPE32402.1 - 4.4e-07 29.2 0.0 7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EPE32402.1 - 5e-06 25.9 0.1 8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain GtrA PF04138.9 EPE32403.1 - 0.012 15.5 8.7 0.019 14.9 0.9 2.2 2 0 0 2 2 2 0 GtrA-like protein MARVEL PF01284.18 EPE32403.1 - 0.051 13.3 11.9 0.37 10.5 7.8 2.1 1 1 1 2 2 2 0 Membrane-associating domain DUF2189 PF09955.4 EPE32403.1 - 0.091 12.7 13.6 0.56 10.1 3.7 2.5 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) ATP-synt_8 PF00895.15 EPE32403.1 - 0.11 12.6 0.7 4.6 7.5 0.0 3.0 3 0 0 3 3 3 0 ATP synthase protein 8 ThiW PF09512.5 EPE32403.1 - 0.68 9.7 6.9 0.18 11.6 0.9 2.5 1 1 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) DUF1751 PF08551.5 EPE32403.1 - 3 8.2 6.3 0.33 11.2 0.4 2.2 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) RNA_pol_Rpc34 PF05158.7 EPE32405.1 - 1.3e-90 303.8 0.0 1.7e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 EPE32405.1 - 0.0065 16.8 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 Replication protein A C terminal MarR PF01047.17 EPE32405.1 - 0.085 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 MarR family Pro_isomerase PF00160.16 EPE32406.1 - 6.7e-40 136.8 0.2 8.6e-40 136.4 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 EPE32407.1 - 1.1e-46 157.7 0.1 1.6e-46 157.2 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EPE32407.1 - 0.00092 17.9 0.0 0.0013 17.4 0.0 1.2 1 0 0 1 1 1 1 ANTH domain TPR_11 PF13414.1 EPE32408.1 - 1.4e-56 187.9 31.8 2.6e-18 65.4 1.4 6.4 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 EPE32408.1 - 7.6e-45 148.7 23.8 1.1e-06 27.9 0.9 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EPE32408.1 - 1.9e-36 121.0 27.2 7.5e-05 22.3 0.4 9.8 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 EPE32408.1 - 1.7e-18 66.7 13.6 7.5e-05 23.2 0.1 6.4 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 EPE32408.1 - 1.7e-18 66.3 18.3 3.5e-10 39.6 1.1 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPE32408.1 - 2.3e-17 61.3 24.1 0.0026 17.4 0.1 8.3 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EPE32408.1 - 1.4e-13 50.1 15.0 0.37 11.5 0.1 8.8 5 3 5 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPE32408.1 - 2.7e-12 45.8 13.7 0.0019 18.2 0.1 8.6 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPE32408.1 - 6.9e-12 44.2 14.4 0.0064 16.2 0.5 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPE32408.1 - 1.9e-10 40.9 16.7 3.8e-05 23.9 0.5 6.1 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPE32408.1 - 1.5e-07 31.1 6.9 0.02 14.7 0.0 5.3 4 2 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EPE32408.1 - 0.00027 21.0 14.0 0.05 13.7 1.3 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EPE32408.1 - 0.025 14.6 0.1 0.025 14.6 0.1 4.8 4 3 3 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPE32408.1 - 0.026 14.9 28.2 0.46 11.0 0.2 7.7 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPE32408.1 - 0.043 13.7 0.2 0.043 13.7 0.1 3.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 EPE32408.1 - 0.079 12.7 14.8 0.11 12.2 1.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF357 PF04010.8 EPE32408.1 - 0.11 12.2 9.4 1.5 8.5 0.9 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF357) SHNi-TPR PF10516.4 EPE32408.1 - 0.12 11.6 2.6 14 5.0 0.0 4.4 5 0 0 5 5 5 0 SHNi-TPR PH_6 PF15406.1 EPE32409.1 - 3.7e-43 146.1 5.6 3.7e-43 146.1 3.9 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain Tho2 PF11262.3 EPE32409.1 - 1.7 7.5 4.8 2.6 7.0 3.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Ycf1 PF05758.7 EPE32409.1 - 6.2 4.4 9.4 7.5 4.1 6.5 1.3 1 0 0 1 1 1 0 Ycf1 Cyclase PF04199.8 EPE32412.1 - 7.9e-18 64.7 0.2 1.1e-17 64.2 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase adh_short PF00106.20 EPE32413.1 - 1e-24 87.2 0.0 1.5e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE32413.1 - 1.6e-16 60.7 0.0 2.1e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE32413.1 - 2.1e-05 24.2 0.0 3.8e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE32413.1 - 0.00031 20.2 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE32413.1 - 0.0011 18.9 0.1 0.0024 17.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding tRNA-synt_2 PF00152.15 EPE32415.1 - 1e-76 257.8 0.0 1.3e-76 257.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EPE32415.1 - 5.2e-06 25.8 0.0 0.0021 17.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EPE32415.1 - 0.0057 16.2 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-codon PF01336.20 EPE32415.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain zf-Tim10_DDP PF02953.10 EPE32416.1 - 5.1e-23 80.1 2.0 5.9e-23 79.9 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.4 EPE32416.1 - 0.0027 17.3 2.7 0.008 15.7 0.1 2.2 2 0 0 2 2 2 1 Mitochondrial import receptor subunit or translocase PG_binding_1 PF01471.13 EPE32417.1 - 0.0014 18.5 0.0 0.82 9.6 0.0 3.5 3 0 0 3 3 3 1 Putative peptidoglycan binding domain ADIP PF11559.3 EPE32417.1 - 0.0031 17.4 0.3 0.0072 16.2 0.2 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Transposase_22 PF02994.9 EPE32417.1 - 0.057 11.9 3.4 0.087 11.3 2.3 1.2 1 0 0 1 1 1 0 L1 transposable element NPV_P10 PF05531.7 EPE32417.1 - 0.064 13.5 0.4 15 5.8 0.0 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EPE32417.1 - 0.085 12.6 1.7 0.22 11.3 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fungal_trans_2 PF11951.3 EPE32417.1 - 0.19 10.2 0.0 0.33 9.4 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain APG6 PF04111.7 EPE32417.1 - 0.29 10.1 1.9 0.57 9.1 1.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Laminin_II PF06009.7 EPE32417.1 - 0.35 10.6 1.9 4.1 7.1 0.5 2.4 1 1 1 2 2 2 0 Laminin Domain II Tropomyosin_1 PF12718.2 EPE32417.1 - 1.3 8.8 8.1 0.091 12.6 1.7 1.9 2 0 0 2 2 2 0 Tropomyosin like CLTH PF10607.4 EPE32418.1 - 7.9e-29 100.2 0.0 2.1e-28 98.8 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EPE32418.1 - 8.4e-19 67.0 0.5 1.9e-18 65.9 0.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EPE32418.1 - 4.6e-05 22.7 0.0 6.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EPE32418.1 - 0.00095 18.9 0.2 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE32418.1 - 0.0013 18.6 0.5 0.0023 17.9 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Syntaxin PF00804.20 EPE32418.1 - 0.0027 17.8 0.1 0.008 16.3 0.1 1.7 1 0 0 1 1 1 1 Syntaxin zf-RING_5 PF14634.1 EPE32418.1 - 0.0063 16.2 0.2 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE32418.1 - 0.015 14.9 0.3 0.026 14.1 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE32418.1 - 0.084 12.5 0.3 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UBN2_2 PF14227.1 EPE32418.1 - 0.14 11.6 0.1 0.33 10.5 0.1 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type PPP4R2 PF09184.6 EPE32419.1 - 4.5e-09 36.2 0.1 4.5e-09 36.2 0.0 2.4 2 1 0 2 2 2 1 PPP4R2 ECH PF00378.15 EPE32422.1 - 1.9e-35 122.1 0.1 2e-35 122.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3469 PF11952.3 EPE32422.1 - 0.037 13.6 0.1 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) Ribonuc_L-PSP PF01042.16 EPE32423.1 - 4.3e-39 133.0 0.0 4.8e-39 132.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP End_N_terminal PF12218.3 EPE32424.1 - 0.083 12.3 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase GATA PF00320.22 EPE32425.1 - 5.7e-16 57.5 4.9 1e-15 56.7 3.4 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EPE32425.1 - 4.8e-13 49.0 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EPE32425.1 - 1.3e-11 44.2 0.0 3.2e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EPE32425.1 - 2.3e-11 43.9 0.0 5.3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.1 EPE32425.1 - 5e-07 29.6 0.0 9.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EPE32425.1 - 7.3e-07 29.1 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold DUF4428 PF14471.1 EPE32425.1 - 1.4 8.7 4.1 0.43 10.3 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) POT1 PF02765.12 EPE32426.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Tht1 PF04163.7 EPE32426.1 - 1.5 7.1 1.2 2.4 6.4 0.9 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Epimerase PF01370.16 EPE32427.1 - 2.5e-14 53.2 0.0 5.7e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE32427.1 - 4e-06 25.7 0.0 5.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPE32427.1 - 6.3e-06 26.3 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPE32427.1 - 0.00013 20.9 0.2 0.0011 17.9 0.2 2.0 1 1 0 1 1 1 1 Male sterility protein Flavin_Reduct PF01613.13 EPE32431.1 - 5.2e-17 62.1 0.0 2.6e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 Flavin reductase like domain Vps5 PF09325.5 EPE32433.1 - 1.8e-87 292.4 7.0 2.8e-87 291.8 4.8 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EPE32433.1 - 5.4e-23 80.9 0.0 1.3e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 PX domain BAR PF03114.13 EPE32433.1 - 0.014 14.8 5.7 0.021 14.3 4.0 1.2 1 0 0 1 1 1 0 BAR domain G6PD_bact PF10786.4 EPE32433.1 - 0.03 13.7 0.3 0.05 13.0 0.2 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Med11 PF10280.4 EPE32434.1 - 3e-32 111.1 0.0 3.6e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein WD40 PF00400.27 EPE32435.1 - 2.8e-54 179.1 27.8 2.1e-12 46.3 0.7 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EPE32435.1 - 8.8e-44 149.0 0.6 1.2e-43 148.5 0.4 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EPE32435.1 - 0.001 18.7 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 EPE32435.1 - 0.027 12.6 1.5 2.1 6.3 0.1 2.6 1 1 0 3 3 3 0 Nucleoporin Nup120/160 Nucleos_tra2_C PF07662.8 EPE32437.1 - 2.3e-68 229.8 5.7 2.3e-68 229.8 4.0 2.5 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EPE32437.1 - 7e-21 74.3 5.6 7e-21 74.3 3.9 3.8 4 1 1 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 EPE32437.1 - 7.4e-06 25.8 6.3 7.4e-06 25.8 4.4 4.2 3 1 1 4 4 4 1 Nucleoside recognition Abhydrolase_6 PF12697.2 EPE32438.1 - 1.5e-22 80.6 0.0 2.2e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE32438.1 - 1.7e-05 24.5 0.0 3e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE32438.1 - 0.0039 16.7 0.0 0.0072 15.8 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1057 PF06342.7 EPE32438.1 - 0.075 11.8 0.0 0.97 8.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) adh_short PF00106.20 EPE32439.1 - 2.9e-14 53.3 1.1 6.7e-14 52.1 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE32439.1 - 6e-05 22.7 0.2 0.0001 22.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EPE32439.1 - 0.011 15.7 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EPE32439.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE32439.1 - 0.072 13.0 0.3 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding adh_short_C2 PF13561.1 EPE32439.1 - 0.094 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DAGK_prokar PF01219.14 EPE32439.1 - 0.14 11.7 0.1 0.29 10.7 0.1 1.5 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase DUF1776 PF08643.5 EPE32439.1 - 0.17 11.0 0.0 0.43 9.6 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Clr5 PF14420.1 EPE32440.1 - 2.8e-19 68.7 5.8 5.9e-19 67.7 4.0 1.6 1 0 0 1 1 1 1 Clr5 domain DUF543 PF04418.7 EPE32440.1 - 0.1 12.5 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) SMI1_KNR4 PF09346.5 EPE32446.1 - 3.2e-07 30.4 0.5 8.4e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.1 EPE32446.1 - 1.8e-06 28.4 0.4 7.7e-06 26.3 0.0 2.1 2 1 0 2 2 2 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.1 EPE32446.1 - 3.2e-05 23.3 1.3 6.4e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall Fasciclin PF02469.17 EPE32448.1 - 1.6e-47 160.6 1.4 2.1e-26 92.4 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain EFG_IV PF03764.13 EPE32448.1 - 0.034 13.7 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G, domain IV Glyco_transf_20 PF00982.16 EPE32449.1 - 1.6e-150 501.7 0.0 2.1e-150 501.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPE32449.1 - 4.6e-77 258.0 0.0 2e-76 256.0 0.0 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EPE32449.1 - 0.014 15.0 0.0 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HD_assoc PF13286.1 EPE32449.1 - 0.065 13.5 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Phosphohydrolase-associated domain Glyco_trans_1_4 PF13692.1 EPE32449.1 - 0.077 13.1 0.0 1.3 9.2 0.0 2.8 2 1 0 2 2 2 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EPE32449.1 - 0.078 12.4 0.1 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Nnf1 PF03980.9 EPE32452.1 - 9.9e-25 86.6 0.0 1.3e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Nnf1 SlyX PF04102.7 EPE32452.1 - 0.0004 20.7 0.4 0.27 11.6 0.1 2.6 2 0 0 2 2 2 2 SlyX bZIP_1 PF00170.16 EPE32452.1 - 0.041 13.8 0.5 0.09 12.7 0.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 EPE32452.1 - 0.059 13.2 0.1 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Adenine_glyco PF03352.8 EPE32452.1 - 0.062 12.8 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyladenine glycosylase DUF641 PF04859.7 EPE32452.1 - 0.094 12.4 0.5 0.26 11.0 0.3 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Mito_fiss_reg PF05308.6 EPE32452.1 - 1.5 8.1 12.9 0.16 11.2 1.1 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.14 EPE32452.1 - 3.6 6.7 11.8 0.25 10.5 1.1 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF899 PF05988.7 EPE32453.1 - 1.5e-68 230.4 0.0 1.9e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Glyco_hydro_3 PF00933.16 EPE32454.1 - 8.4e-93 310.6 0.0 1.3e-92 310.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE32454.1 - 8.9e-57 192.2 0.4 7e-56 189.2 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE32454.1 - 5.7e-14 51.8 0.0 1.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ERG4_ERG24 PF01222.12 EPE32456.1 - 2.8e-167 556.6 5.0 3.2e-167 556.4 3.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Man-6-P_recep PF02157.10 EPE32457.1 - 1.6e-09 37.2 0.0 2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 EPE32457.1 - 1.7e-09 37.5 0.0 0.00087 19.0 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 EPE32457.1 - 6.1e-08 32.2 9.0 3.8e-05 23.0 6.3 3.3 1 1 0 1 1 1 1 Autophagy-related protein 27 FAD_binding_7 PF03441.9 EPE32458.1 - 8.9e-84 280.9 0.0 1.6e-83 280.1 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EPE32458.1 - 1e-35 122.8 0.1 3.3e-35 121.2 0.1 1.8 2 0 0 2 2 2 1 DNA photolyase PH_9 PF15410.1 EPE32459.1 - 0.00085 19.4 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain Methyltransf_31 PF13847.1 EPE32461.1 - 7e-17 61.4 0.0 1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE32461.1 - 2.6e-14 53.7 0.0 3.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE32461.1 - 1.5e-05 25.3 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE32461.1 - 2.6e-05 24.4 0.0 4.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE32461.1 - 3.8e-05 23.7 0.0 8.1e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPE32461.1 - 0.0039 16.8 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE32461.1 - 0.022 14.4 0.1 0.091 12.4 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_3 PF01596.12 EPE32461.1 - 0.028 13.4 0.0 0.077 12.0 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_11 PF08241.7 EPE32461.1 - 0.035 14.5 0.1 0.1 13.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EPE32461.1 - 0.088 12.1 0.0 0.23 10.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Cytochrom_B561 PF03188.11 EPE32462.1 - 3.1e-07 30.2 7.4 1.1e-06 28.4 4.9 2.0 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EPE32462.1 - 0.0099 15.4 4.7 0.022 14.3 3.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) NfeD PF01957.13 EPE32462.1 - 0.12 12.5 2.9 0.13 12.3 0.2 2.4 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding FA_desaturase PF00487.19 EPE32462.1 - 0.4 10.0 19.5 0.012 15.0 5.8 2.2 1 1 1 2 2 2 0 Fatty acid desaturase Na_K-ATPase PF00287.13 EPE32463.1 - 0.08 11.7 0.5 0.19 10.4 0.1 1.7 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain F-box-like PF12937.2 EPE32463.1 - 0.34 10.6 4.3 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 F-box-like DUF4215 PF13948.1 EPE32464.1 - 9.5e-06 25.7 4.3 4.1e-05 23.6 3.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4215) zf-NADH-PPase PF09297.6 EPE32464.1 - 0.99 8.9 5.8 11 5.6 0.5 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Cmyb_C PF09316.5 EPE32464.1 - 5.2 6.6 5.5 8.5 6.0 3.8 1.2 1 0 0 1 1 1 0 C-myb, C-terminal AA_permease_2 PF13520.1 EPE32465.1 - 2.3e-43 148.3 48.6 3.4e-43 147.7 33.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE32465.1 - 1.1e-23 83.4 39.8 2e-23 82.5 27.6 1.3 1 1 0 1 1 1 1 Amino acid permease Apc4 PF12896.2 EPE32466.1 - 2.9e-58 196.6 0.3 5e-58 195.8 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EPE32466.1 - 2.3e-19 68.5 0.0 1.4e-15 56.4 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EPE32466.1 - 0.0032 17.3 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Pik1 PF11522.3 EPE32466.1 - 0.075 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Adap_comp_sub PF00928.16 EPE32467.1 - 2.8e-16 59.3 0.0 4.7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EPE32467.1 - 8.1e-07 28.8 0.3 1.5e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2420 PF10336.4 EPE32468.1 - 2.5e-10 39.9 0.0 4.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.9 EPE32469.1 - 1.8e-108 362.0 13.0 2.3e-108 361.7 9.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EPE32469.1 - 1.1e-07 31.9 2.8 1.1e-07 31.9 2.0 3.2 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EPE32469.1 - 0.0005 20.1 9.6 0.0005 20.1 6.6 3.2 2 2 0 2 2 2 1 EamA-like transporter family DUF4405 PF14358.1 EPE32469.1 - 0.36 10.9 5.1 3.1 8.0 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) Acyl_transf_3 PF01757.17 EPE32469.1 - 0.66 8.7 17.3 2.3 6.9 9.7 2.2 1 1 1 2 2 2 0 Acyltransferase family NfeD PF01957.13 EPE32469.1 - 2.5 8.2 14.8 1.6 8.8 0.1 3.3 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding Ribosomal_S3_C PF00189.15 EPE32470.1 - 1.1e-16 60.7 0.1 2.5e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EPE32470.1 - 2.5e-12 46.1 0.1 4.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EPE32470.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.9 EPE32472.1 - 2e-121 405.0 0.0 2.7e-121 404.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EPE32472.1 - 0.019 15.2 0.0 0.054 13.7 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family HEAT PF02985.17 EPE32473.1 - 6.2e-44 144.1 18.1 0.0027 17.6 0.1 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EPE32473.1 - 5.7e-34 116.2 3.4 6.3e-09 36.0 0.0 7.9 2 2 6 8 8 8 8 HEAT repeats HEAT_EZ PF13513.1 EPE32473.1 - 1e-12 48.1 7.0 0.0069 16.8 0.0 8.5 7 1 2 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPE32473.1 - 1.3e-11 44.7 4.7 0.0025 18.1 0.1 7.7 5 1 4 9 9 9 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EPE32473.1 - 2.1e-07 29.6 7.4 4.8e-05 21.8 1.0 5.0 2 1 2 4 4 4 4 Adaptin N terminal region DUF2435 PF10363.4 EPE32473.1 - 0.0017 18.1 4.7 0.74 9.7 0.1 4.4 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) CLASP_N PF12348.3 EPE32473.1 - 0.0025 17.2 1.7 0.74 9.1 0.1 4.4 3 2 2 5 5 5 2 CLASP N terminal Cnd3 PF12719.2 EPE32473.1 - 0.0029 16.6 0.2 0.028 13.4 0.1 2.5 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 EPE32473.1 - 0.0031 17.2 4.3 2.2 8.2 0.0 5.2 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 EPE32473.1 - 0.019 13.2 4.6 0.54 8.4 0.0 2.8 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit RIX1 PF08167.7 EPE32473.1 - 0.039 13.6 0.1 1.4 8.5 0.0 3.3 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis MadL PF03817.8 EPE32473.1 - 0.062 13.1 0.1 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Malonate transporter MadL subunit Cnd1 PF12717.2 EPE32473.1 - 0.21 11.4 7.5 24 4.7 0.0 5.1 3 1 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 B3_4 PF03483.12 EPE32474.1 - 6.6e-26 90.8 0.0 1.1e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EPE32474.1 - 4.7e-17 61.5 0.0 8.2e-15 54.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 EPE32474.1 - 0.093 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein MIP PF00230.15 EPE32478.1 - 1.3e-47 162.2 13.3 1.6e-47 161.8 9.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Zn_clus PF00172.13 EPE32479.1 - 0.0013 18.6 23.7 0.0061 16.4 4.2 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE32480.1 - 1.8e-18 66.4 54.3 1.4e-13 50.3 15.7 2.6 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EPE32480.1 - 6.2e-12 44.5 14.6 1.9e-11 42.9 10.1 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.23 EPE32481.1 - 1.7e-24 86.0 0.0 2.5e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.10 EPE32481.1 - 2.8e-11 42.5 0.0 4.5e-05 22.0 0.0 2.8 3 0 0 3 3 3 2 Transferase family PP-binding PF00550.20 EPE32481.1 - 3.6e-08 33.5 0.0 8.6e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ABC2_membrane PF01061.19 EPE32483.1 - 9e-91 302.7 54.6 9.5e-48 162.1 17.1 2.5 3 0 0 3 3 3 2 ABC-2 type transporter DIT1_PvcA PF05141.7 EPE32483.1 - 1.3e-86 290.3 0.0 1.9e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein ABC_tran PF00005.22 EPE32483.1 - 4.6e-33 114.4 0.0 1.5e-15 57.7 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EPE32483.1 - 6.7e-33 112.4 8.6 1e-31 108.6 0.0 3.4 4 0 0 4 4 4 2 CDR ABC transporter DUF4066 PF13278.1 EPE32483.1 - 2.5e-22 78.9 0.0 5.1e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Putative amidotransferase ABC_trans_N PF14510.1 EPE32483.1 - 2.3e-20 72.4 0.0 5.8e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DJ-1_PfpI PF01965.19 EPE32483.1 - 1.3e-11 44.1 0.1 2.5e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ABC2_membrane_3 PF12698.2 EPE32483.1 - 5.9e-08 32.1 37.9 2.1e-05 23.7 8.0 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EPE32483.1 - 3.3e-07 29.9 0.0 7.6e-05 22.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EPE32483.1 - 0.00014 21.0 0.0 0.016 14.4 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPE32483.1 - 0.00092 18.6 1.1 0.066 12.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EPE32483.1 - 0.0022 18.0 0.4 0.13 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EPE32483.1 - 0.0038 16.6 0.4 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EPE32483.1 - 0.0055 16.5 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE32483.1 - 0.0065 16.6 0.1 1.8 8.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EPE32483.1 - 0.011 16.0 0.0 0.32 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EPE32483.1 - 0.016 14.4 0.0 0.39 9.9 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EPE32483.1 - 0.15 11.7 1.1 7.9 6.1 0.1 2.9 2 0 0 2 2 2 0 NACHT domain Methyltransf_2 PF00891.13 EPE32484.1 - 1.4e-29 103.0 0.1 1.9e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EPE32484.1 - 0.0024 18.4 0.0 0.0057 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE32484.1 - 0.003 18.0 0.0 0.014 15.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPE32484.1 - 0.0097 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EPE32484.1 - 0.0099 14.9 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EPE32484.1 - 0.021 14.4 0.0 0.048 13.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EPE32484.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EPE32484.1 - 0.071 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PRMT5 PF05185.11 EPE32484.1 - 0.082 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DUF938 PF06080.7 EPE32484.1 - 0.095 12.2 0.0 0.32 10.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF938) CheR PF01739.13 EPE32484.1 - 0.15 11.2 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain T5orf172 PF10544.4 EPE32485.1 - 2.8e-15 56.5 0.6 6.3e-15 55.3 0.1 1.9 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.1 EPE32485.1 - 3.3e-15 56.2 0.5 1.1e-14 54.6 0.1 2.1 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 NmrA PF05368.8 EPE32486.1 - 4.7e-12 45.6 0.1 4.4e-05 22.8 0.0 2.2 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EPE32486.1 - 0.0017 18.4 0.3 0.12 12.3 0.1 2.3 1 1 1 2 2 2 2 NADH(P)-binding Semialdhyde_dh PF01118.19 EPE32486.1 - 0.019 15.2 0.0 0.055 13.7 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GIT_SHD PF08518.6 EPE32486.1 - 0.12 11.7 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT ADH_zinc_N PF00107.21 EPE32488.1 - 3.6e-25 88.0 0.4 6e-25 87.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE32488.1 - 2.4e-13 51.0 0.1 6.8e-13 49.6 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE32488.1 - 8.3e-11 41.6 0.1 1.3e-09 37.8 0.1 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Mem_trans PF03547.13 EPE32490.1 - 3.4e-24 84.8 0.0 4.5e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein NapE PF06796.6 EPE32490.1 - 0.13 11.5 4.0 0.25 10.6 0.0 3.2 3 0 0 3 3 3 0 Periplasmic nitrate reductase protein NapE Hydrophobin_2 PF06766.6 EPE32491.1 - 3.8e-23 80.9 9.7 4.9e-23 80.5 6.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CPL PF08144.6 EPE32492.1 - 2.3e-19 69.7 0.0 3.2e-18 65.9 0.0 2.9 2 0 0 2 2 2 1 CPL (NUC119) domain RWD PF05773.17 EPE32493.1 - 8.9e-23 80.3 0.1 1.9e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 RWD domain Cwf_Cwc_15 PF04889.7 EPE32493.1 - 0.097 12.3 5.9 0.17 11.5 4.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPR_11 PF13414.1 EPE32494.1 - 6.6e-11 41.7 0.0 2e-05 24.1 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 EPE32494.1 - 2.6e-10 40.1 2.9 0.00079 19.3 0.4 4.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPE32494.1 - 2.7e-10 39.3 0.0 0.00077 19.1 0.0 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE32494.1 - 9.2e-10 38.9 5.1 0.00027 21.5 0.1 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPE32494.1 - 2.6e-08 33.7 5.5 0.31 11.7 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPE32494.1 - 3.8e-08 33.5 6.6 0.0048 17.2 0.5 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPE32494.1 - 2.7e-07 29.8 1.6 0.01 15.5 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPE32494.1 - 2.8e-06 26.6 0.0 0.0065 16.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPE32494.1 - 6.7e-05 22.3 0.0 0.0012 18.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EPE32494.1 - 0.00075 19.5 0.0 2.5 8.5 0.0 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EPE32494.1 - 0.0054 16.8 0.0 0.14 12.3 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EPE32494.1 - 0.027 14.4 10.2 1.9 8.5 0.1 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPE32494.1 - 0.053 13.9 3.4 27 5.5 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPE32494.1 - 4.3 8.0 9.9 17 6.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Rad51 PF08423.6 EPE32497.1 - 1.1e-138 460.3 0.0 1.4e-138 460.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EPE32497.1 - 1.5e-13 50.6 0.0 2.1e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EPE32497.1 - 4.2e-07 30.0 0.2 1.2e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 EPE32497.1 - 4.5e-07 29.2 0.0 6e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EPE32497.1 - 5.3e-06 25.7 0.0 1e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.6 EPE32497.1 - 0.056 12.2 0.1 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein DnaB_C PF03796.10 EPE32497.1 - 0.067 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Nup160 PF11715.3 EPE32498.1 - 3.2e-126 421.6 0.7 4.3e-126 421.2 0.5 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Acetyltransf_7 PF13508.1 EPE32498.1 - 0.025 14.7 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Vps26 PF03643.10 EPE32499.1 - 8.5e-124 411.7 0.4 9.8e-124 411.5 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EPE32499.1 - 0.00025 20.8 0.1 1.6 8.5 0.0 3.6 2 1 2 4 4 4 3 Arrestin (or S-antigen), N-terminal domain PAT1 PF09770.4 EPE32500.1 - 4e-243 809.2 17.0 1.4e-241 804.1 11.8 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF746 PF05344.6 EPE32500.1 - 0.026 14.0 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) DUF3533 PF12051.3 EPE32501.1 - 6.2e-121 403.7 15.5 7.1e-121 403.5 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF1524 PF07510.6 EPE32502.1 - 5.7e-13 48.9 0.0 6.8e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 EPE32502.1 - 0.11 12.1 0.3 0.35 10.5 0.2 1.7 1 1 0 1 1 1 0 HNH endonuclease WD40 PF00400.27 EPE32504.1 - 1.7e-36 122.7 9.7 2.2e-10 40.0 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EPE32504.1 - 2.3e-07 29.3 7.0 0.076 11.1 0.0 4.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 APG6 PF04111.7 EPE32504.1 - 0.0025 16.9 4.0 0.0038 16.3 2.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 PQQ_2 PF13360.1 EPE32504.1 - 0.011 15.1 0.8 0.16 11.4 0.0 2.6 2 1 0 3 3 3 0 PQQ-like domain Nup54 PF13874.1 EPE32504.1 - 0.07 12.7 2.6 0.11 12.1 0.8 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 TBPIP PF07106.8 EPE32504.1 - 0.22 11.0 4.5 0.2 11.2 1.9 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cortex-I_coil PF09304.5 EPE32504.1 - 0.6 10.1 10.5 2.2 8.3 4.2 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil IncA PF04156.9 EPE32504.1 - 1.2 8.6 9.2 2 7.9 6.4 1.2 1 0 0 1 1 1 0 IncA protein CM_2 PF01817.16 EPE32505.1 - 3.4e-07 30.2 0.0 3.9e-05 23.6 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II BCIP PF13862.1 EPE32506.1 - 2.2e-69 232.8 0.1 2.7e-69 232.5 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein GMP_synt_C PF00958.17 EPE32507.1 - 2.7e-37 126.3 0.0 5.7e-37 125.3 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EPE32507.1 - 3.6e-37 127.6 0.0 6e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EPE32507.1 - 5.1e-11 41.9 0.0 3.7e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EPE32507.1 - 7.4e-09 35.3 0.1 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 EPE32507.1 - 0.00051 18.7 0.0 0.0015 17.2 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 EPE32507.1 - 0.0019 17.5 0.0 0.0078 15.5 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 EPE32507.1 - 0.0021 17.5 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EPE32507.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Arginosuc_synth PF00764.14 EPE32507.1 - 0.031 13.3 0.1 0.052 12.5 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.14 EPE32507.1 - 0.057 13.2 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 EPE32507.1 - 0.083 12.3 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 PP-loop family SH3_9 PF14604.1 EPE32508.1 - 7e-06 25.5 0.1 1.5e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPE32508.1 - 0.00032 20.0 0.5 0.0007 18.9 0.4 1.5 1 0 0 1 1 1 1 SH3 domain VSP PF03302.8 EPE32508.1 - 0.00083 18.0 17.1 0.0013 17.4 11.8 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF2668 PF10873.3 EPE32508.1 - 0.0054 16.9 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) Sporozoite_P67 PF05642.6 EPE32509.1 - 9.3 3.9 9.8 6.1 4.5 6.0 1.2 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.20 EPE32510.1 - 8.3e-24 84.1 0.0 1.5e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EPE32510.1 - 1.7e-10 40.3 9.3 6e-05 22.7 0.3 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 EPE32510.1 - 6.9e-07 28.8 1.9 0.67 10.1 0.1 6.3 6 0 0 6 6 6 1 HEAT repeat Pkinase_Tyr PF07714.12 EPE32510.1 - 2.2e-06 26.9 0.0 3.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EPE32510.1 - 0.00049 20.3 0.5 3.9 7.8 0.0 3.9 2 1 1 3 3 3 2 HEAT repeats DUF3958 PF13125.1 EPE32510.1 - 0.19 11.6 0.1 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) LRR_9 PF14580.1 EPE32511.1 - 8.1e-49 165.5 0.6 1.1e-48 165.1 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 EPE32511.1 - 3.6e-09 36.2 2.8 1.9e-08 33.8 0.8 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 EPE32511.1 - 1.7e-06 27.5 8.6 7.7e-06 25.4 1.9 3.9 3 1 0 4 4 4 1 Leucine Rich repeats (2 copies) DUF4570 PF15134.1 EPE32511.1 - 0.02 14.6 0.1 0.77 9.6 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) LRR_7 PF13504.1 EPE32511.1 - 0.059 13.5 3.1 4.5 7.9 0.1 4.3 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 EPE32511.1 - 0.092 12.8 2.3 1.8 8.8 0.1 3.8 3 1 1 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 EPE32511.1 - 0.28 11.3 5.5 21 5.6 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat CBFD_NFYB_HMF PF00808.18 EPE32512.1 - 2.1e-08 34.1 0.3 3.2e-08 33.5 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Voltage_CLC PF00654.15 EPE32513.1 - 7.8e-89 298.1 26.9 7.8e-89 298.1 18.7 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel Glyco_hydro_43 PF04616.9 EPE32513.1 - 2e-64 217.4 1.7 3.1e-64 216.8 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBS PF00571.23 EPE32513.1 - 7.8e-12 44.7 0.1 0.0001 22.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain C2 PF00168.25 EPE32513.1 - 3.6e-09 36.3 0.0 7.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain Lactonase PF10282.4 EPE32514.1 - 2.1e-63 214.4 0.0 2.6e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Kelch_5 PF13854.1 EPE32515.1 - 2.4e-18 65.6 9.2 3.4e-09 36.4 0.1 5.2 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EPE32515.1 - 1.5e-13 50.3 10.3 0.00015 21.4 0.9 6.1 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EPE32515.1 - 2.8e-11 43.2 12.2 0.00032 20.7 0.0 6.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EPE32515.1 - 3e-09 36.6 13.8 0.0086 16.2 0.1 5.9 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EPE32515.1 - 4e-08 32.7 1.3 0.0056 16.3 0.2 4.2 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 EPE32515.1 - 9.4e-05 21.8 9.9 1 8.9 0.3 4.9 4 0 0 4 4 4 2 Kelch motif SKG6 PF08693.5 EPE32515.1 - 0.13 11.6 0.2 0.46 9.8 0.1 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TraB PF01963.12 EPE32516.1 - 0.046 13.1 1.9 0.061 12.7 1.3 1.1 1 0 0 1 1 1 0 TraB family DsbD PF02683.10 EPE32516.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region COX14 PF14880.1 EPE32517.1 - 1.8e-18 65.8 0.2 4.3e-18 64.6 0.1 1.7 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF2458 PF10454.4 EPE32518.1 - 2.4e-46 157.3 0.2 3.4e-46 156.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Thiolase_N PF00108.18 EPE32519.1 - 1.3e-77 260.4 0.3 1.9e-77 259.8 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPE32519.1 - 5.4e-40 135.6 0.7 1.3e-39 134.3 0.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EPE32519.1 - 0.002 17.6 2.7 0.0021 17.6 0.5 1.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EPE32519.1 - 0.39 10.4 3.1 3.3 7.4 0.1 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DAHP_synth_1 PF00793.15 EPE32521.1 - 9e-100 332.8 0.2 1.1e-99 332.5 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Aldo_ket_red PF00248.16 EPE32522.1 - 8.4e-63 211.8 0.0 1.1e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Med19 PF10278.4 EPE32523.1 - 1.7 8.3 10.8 0.57 9.8 3.9 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 zf-MYND PF01753.13 EPE32524.1 - 8.4e-11 41.5 12.0 2.1e-10 40.2 8.3 1.7 1 0 0 1 1 1 1 MYND finger DUF3844 PF12955.2 EPE32524.1 - 0.51 10.4 10.8 0.62 10.2 4.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3844) ADH_N PF08240.7 EPE32525.1 - 8.7e-27 93.0 2.2 1.5e-26 92.2 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE32525.1 - 1.7e-08 34.0 0.4 4.5e-08 32.7 0.3 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EPE32525.1 - 0.00055 18.5 1.1 0.0036 15.8 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein ADH_N_assoc PF13823.1 EPE32525.1 - 0.0022 17.6 0.0 0.0063 16.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ABM PF03992.11 EPE32526.1 - 2.3e-08 33.9 0.0 2.9e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3734 PF12536.3 EPE32526.1 - 0.13 12.4 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Patatin phospholipase DUF3804 PF12707.2 EPE32526.1 - 0.14 11.6 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) SNARE_assoc PF09335.6 EPE32527.1 - 2.4e-17 63.2 8.3 2.4e-17 63.2 5.7 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF3278 PF11683.3 EPE32527.1 - 0.00011 22.1 3.2 0.00055 19.9 1.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3278) DUF4519 PF15012.1 EPE32527.1 - 0.0088 15.9 1.4 0.0088 15.9 0.9 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4519) Cyt_c_ox_IV PF12270.3 EPE32527.1 - 0.063 13.0 0.2 0.063 13.0 0.1 2.9 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV DUF3753 PF12575.3 EPE32527.1 - 0.21 11.4 8.0 0.7 9.7 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3753) RseC_MucC PF04246.7 EPE32527.1 - 8 6.0 6.2 28 4.2 0.3 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC MFS_1 PF07690.11 EPE32528.1 - 2.1e-31 108.9 51.8 5.2e-21 74.7 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EPE32528.1 - 1.8e-07 30.8 8.9 4.8e-06 26.2 2.9 3.6 3 0 0 3 3 3 2 MFS_1 like family Sugar_tr PF00083.19 EPE32528.1 - 9.7e-05 21.1 45.5 0.0026 16.4 9.7 2.7 1 1 2 3 3 3 2 Sugar (and other) transporter Fungal_trans PF04082.13 EPE32529.1 - 8.7e-08 31.3 0.0 1.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RhoGAP PF00620.22 EPE32529.1 - 0.13 11.8 0.0 1.5 8.3 0.0 2.5 3 0 0 3 3 3 0 RhoGAP domain Vma12 PF11712.3 EPE32530.1 - 1.5e-38 131.7 0.0 2.2e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2029 PF09594.5 EPE32530.1 - 0.003 17.1 0.9 0.0043 16.5 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) DUF1385 PF07136.6 EPE32530.1 - 0.086 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) polyprenyl_synt PF00348.12 EPE32531.1 - 5e-53 179.5 0.0 7.8e-50 169.1 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Thymosin PF01290.15 EPE32531.1 - 0.032 13.8 0.3 0.072 12.7 0.2 1.6 1 0 0 1 1 1 0 Thymosin beta-4 family MFS_1 PF07690.11 EPE32533.1 - 3.3e-35 121.4 49.9 5.9e-25 87.7 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE32533.1 - 0.00017 20.1 25.3 0.00031 19.2 4.1 2.9 1 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 EPE32533.1 - 0.002 16.7 25.2 0.0041 15.7 17.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 EPE32533.1 - 0.011 14.2 21.7 0.048 12.1 4.3 3.4 2 2 1 3 3 3 0 Vacuole effluxer Atg22 like DHDPS PF00701.17 EPE32535.1 - 1.1e-36 125.9 0.0 1.9e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Toxin_ToxA PF11584.3 EPE32535.1 - 0.092 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA Amidase PF01425.16 EPE32536.1 - 1e-86 291.5 3.9 1.3e-86 291.2 2.7 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.16 EPE32537.1 - 2.8e-69 234.0 0.0 3.5e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Acetyltransf_7 PF13508.1 EPE32537.1 - 4e-07 30.0 0.0 1e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE32537.1 - 2.6e-06 27.3 0.1 5e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE32537.1 - 1.2e-05 25.4 0.2 0.00015 21.8 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE32537.1 - 0.00014 21.8 0.2 0.00032 20.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Fungal_trans PF04082.13 EPE32538.1 - 4.7e-24 84.6 0.1 8.2e-24 83.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE32538.1 - 0.00056 19.7 9.1 0.001 18.9 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.15 EPE32539.1 - 1.6e-56 191.9 1.0 3.1e-56 191.0 0.7 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase DHHW PF14286.1 EPE32540.1 - 0.19 11.0 1.8 0.26 10.5 1.2 1.1 1 0 0 1 1 1 0 DHHW protein Macoilin PF09726.4 EPE32540.1 - 8.2 4.5 8.7 10 4.2 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L50 PF10501.4 EPE32541.1 - 1.6e-15 57.0 0.1 3.7e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S Prok_Ub PF14454.1 EPE32541.1 - 0.13 11.9 0.1 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic Ubiquitin SRA1 PF07304.6 EPE32542.1 - 0.033 13.9 0.4 0.044 13.5 0.3 1.1 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) zf-AN1 PF01428.11 EPE32542.1 - 0.039 13.8 1.0 0.039 13.8 0.7 1.8 2 0 0 2 2 2 0 AN1-like Zinc finger C1_4 PF07975.7 EPE32542.1 - 0.066 13.2 3.6 0.084 12.8 2.0 1.5 1 1 0 1 1 1 0 TFIIH C1-like domain ETRAMP PF09716.5 EPE32542.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) SIR2 PF02146.12 EPE32543.1 - 1.6e-24 86.6 0.0 5.1e-24 84.9 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.3 EPE32544.1 - 3.3e-150 501.5 0.0 4.2e-150 501.1 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 SNF2_N PF00176.18 EPE32545.1 - 4.1e-64 216.2 0.0 6.5e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EPE32545.1 - 5e-23 80.5 11.0 4.8e-14 51.7 0.1 4.2 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 EPE32545.1 - 6.1e-17 61.6 0.0 2.1e-16 59.9 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 EPE32545.1 - 1.2e-12 47.5 0.0 2.9e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.22 EPE32546.1 - 5.2e-35 120.7 0.0 2.5e-16 60.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EPE32546.1 - 7.6e-14 51.0 4.4 7.6e-14 51.0 3.0 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EPE32546.1 - 2e-12 47.6 9.3 0.0041 17.1 1.1 4.9 3 2 0 4 4 4 3 AAA domain SMC_N PF02463.14 EPE32546.1 - 6.5e-11 41.8 0.7 0.0028 16.9 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EPE32546.1 - 6.3e-07 28.7 0.1 0.88 8.5 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 EPE32546.1 - 3e-05 24.8 0.8 0.21 12.4 0.1 3.1 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPE32546.1 - 5.5e-05 22.4 1.0 0.43 9.7 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA PF00004.24 EPE32546.1 - 6.2e-05 23.2 0.2 0.04 14.1 0.1 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE32546.1 - 8.8e-05 22.6 0.0 0.032 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 EPE32546.1 - 0.0001 21.7 2.5 0.0001 21.7 1.7 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_29 PF13555.1 EPE32546.1 - 0.00014 21.3 0.5 0.14 11.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EPE32546.1 - 0.00053 19.4 0.1 0.49 9.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EPE32546.1 - 0.00071 19.8 0.3 1.8 8.8 0.1 2.9 2 1 0 2 2 2 2 AAA domain VirE PF05272.6 EPE32546.1 - 0.0011 18.4 0.1 1.4 8.3 0.0 2.6 2 0 0 2 2 2 2 Virulence-associated protein E RNA_helicase PF00910.17 EPE32546.1 - 0.0013 18.8 0.1 1 9.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Fer4_21 PF14697.1 EPE32546.1 - 0.002 17.9 11.6 0.0039 17.0 8.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.10 EPE32546.1 - 0.0029 16.3 0.0 0.05 12.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Fer4_6 PF12837.2 EPE32546.1 - 0.0036 17.0 10.7 0.0073 16.1 1.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain SRP54 PF00448.17 EPE32546.1 - 0.0038 16.7 1.1 0.2 11.0 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EPE32546.1 - 0.0044 16.9 0.0 0.51 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EPE32546.1 - 0.0048 17.2 3.7 0.18 12.1 0.7 2.7 3 1 0 3 3 2 1 AAA domain Miro PF08477.8 EPE32546.1 - 0.01 16.3 0.2 1.4 9.3 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein UPF0079 PF02367.12 EPE32546.1 - 0.011 15.3 0.3 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EPE32546.1 - 0.012 15.2 0.9 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 EPE32546.1 - 0.012 15.3 0.6 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Fer4_10 PF13237.1 EPE32546.1 - 0.017 14.9 2.0 0.017 14.9 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 EPE32546.1 - 0.03 14.6 1.8 0.03 14.6 1.3 2.4 1 1 0 2 2 2 0 4Fe-4S dicluster domain NB-ARC PF00931.17 EPE32546.1 - 0.036 12.9 0.0 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.1 EPE32546.1 - 0.043 13.7 0.0 3.8 7.4 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EPE32546.1 - 0.054 11.9 0.0 0.054 11.9 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EPE32546.1 - 0.056 13.4 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.12 EPE32546.1 - 0.063 12.6 0.5 18 4.6 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase AAA_5 PF07728.9 EPE32546.1 - 0.081 12.6 0.2 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EPE32546.1 - 0.11 11.9 1.8 0.25 10.8 0.0 2.4 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EPE32546.1 - 0.12 11.8 0.1 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EPE32546.1 - 0.13 11.3 0.1 0.27 10.3 0.1 1.5 1 0 0 1 1 1 0 KaiC MukB PF04310.7 EPE32546.1 - 0.18 11.0 0.5 4.7 6.4 0.0 2.8 3 0 0 3 3 3 0 MukB N-terminal AAA_24 PF13479.1 EPE32546.1 - 0.18 11.3 1.2 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 EPE32546.1 - 0.26 11.3 9.0 0.43 10.6 1.3 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.10 EPE32546.1 - 0.27 10.9 1.1 17 5.0 0.1 2.5 2 0 0 2 2 2 0 NTPase Fer4_9 PF13187.1 EPE32546.1 - 0.49 10.6 12.4 2.3 8.5 8.7 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EPE32546.1 - 1.2 9.1 12.9 0.24 11.4 1.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.14 EPE32547.1 - 1.2e-53 178.8 24.2 6.1e-16 58.1 0.9 7.0 6 1 0 6 6 6 6 FF domain WW PF00397.21 EPE32547.1 - 2.6e-17 62.3 6.7 3.1e-09 36.5 0.1 2.6 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 EPE32548.1 - 3.7e-80 269.4 0.0 6.4e-80 268.7 0.0 1.4 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Glycophorin_A PF01102.13 EPE32549.1 - 0.006 16.3 1.8 0.007 16.1 0.1 1.9 2 0 0 2 2 2 1 Glycophorin A Syndecan PF01034.15 EPE32549.1 - 0.5 10.0 2.0 1.1 8.9 1.4 1.6 1 0 0 1 1 1 0 Syndecan domain Glyco_hydro_18 PF00704.23 EPE32551.1 - 2.8e-66 224.3 0.0 6e-66 223.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EPE32551.1 - 0.00041 20.2 7.8 0.00041 20.2 5.4 3.7 3 0 0 3 3 3 2 Chitin recognition protein LysM PF01476.15 EPE32552.1 - 0.017 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 LysM domain DUF4038 PF13204.1 EPE32554.1 - 0.027 13.8 0.9 4.7 6.4 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4038) Allexi_40kDa PF05549.6 EPE32554.1 - 0.09 12.0 3.8 0.2 10.9 0.1 2.3 2 1 0 2 2 2 0 Allexivirus 40kDa protein IncA PF04156.9 EPE32554.1 - 3.2 7.3 7.1 7.1 6.1 4.9 1.6 1 0 0 1 1 1 0 IncA protein DUF3773 PF12608.3 EPE32556.1 - 0.029 14.4 1.0 3.3 7.8 0.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3773) DUF3328 PF11807.3 EPE32557.1 - 2.1e-36 125.6 1.3 5.3e-36 124.3 0.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EPE32558.1 - 5.3e-20 72.0 0.2 6e-17 62.0 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) V-ATPase_H_N PF03224.9 EPE32559.1 - 1.4e-74 251.0 0.0 3.1e-74 249.9 0.0 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EPE32559.1 - 1.3e-39 134.8 0.2 3.4e-39 133.4 0.1 1.8 1 0 0 1 1 1 1 V-ATPase subunit H GCV_T PF01571.16 EPE32560.1 - 2.3e-64 216.6 0.0 2.9e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EPE32560.1 - 8.5e-25 86.6 0.4 1.6e-24 85.7 0.3 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TrmE_N PF10396.4 EPE32560.1 - 0.019 14.9 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus Sulfate_transp PF00916.15 EPE32561.1 - 1.2e-37 129.4 1.3 2.8e-37 128.2 0.9 1.7 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 EPE32561.1 - 2.4e-18 65.7 0.0 4.3e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EPE32561.1 - 2.1e-10 40.0 0.0 3.8e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.6 EPE32562.1 - 9.8e-13 48.3 0.0 1.6e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein HMG_box PF00505.14 EPE32563.1 - 2.4e-11 43.7 0.3 2.4e-11 43.7 0.2 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPE32563.1 - 0.0055 17.0 0.3 0.014 15.7 0.2 1.8 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EPE32563.1 - 0.037 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 PHD PF00628.24 EPE32564.1 - 4.7e-09 35.7 8.4 9e-09 34.8 5.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EPE32564.1 - 0.0026 17.0 4.9 0.0051 16.0 3.4 1.5 1 0 0 1 1 1 1 PHD-finger DUF2098 PF09871.4 EPE32564.1 - 1.4 8.8 0.0 1.4 8.8 0.0 4.0 1 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2098) Ion_trans PF00520.26 EPE32565.1 - 9.4e-110 364.5 78.5 4e-35 120.8 6.1 5.2 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.27 EPE32565.1 - 0.056 12.7 0.0 0.22 10.9 0.0 2.1 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 EPE32565.1 - 0.17 12.0 0.0 0.51 10.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair DUF2976 PF11190.3 EPE32565.1 - 2.8 7.5 11.1 0.2 11.1 0.2 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2976) T2SF PF00482.18 EPE32566.1 - 0.041 13.7 0.4 0.078 12.8 0.3 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F FPN1 PF06963.7 EPE32568.1 - 1.6e-72 244.3 11.4 2.6e-53 180.9 1.9 2.0 2 0 0 2 2 2 2 Ferroportin1 (FPN1) UCR_Fe-S_N PF10399.4 EPE32568.1 - 2.9 7.1 4.8 2 7.6 1.7 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Copper-fist PF00649.13 EPE32569.1 - 2.2e-18 65.1 0.6 5.8e-18 63.7 0.4 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain Stb3 PF10330.4 EPE32570.1 - 0.0065 16.1 0.1 0.0074 15.9 0.0 1.1 1 0 0 1 1 1 1 Putative Sin3 binding protein Methyltransf_16 PF10294.4 EPE32571.1 - 2.7e-16 59.4 0.0 3.5e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EPE32571.1 - 0.0025 18.3 0.0 0.0038 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EPE32571.1 - 0.0063 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.8 EPE32571.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.12 EPE32571.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Cupin_8 PF13621.1 EPE32572.1 - 3.2e-28 98.9 0.0 9.4e-28 97.3 0.0 1.8 1 1 1 2 2 2 1 Cupin-like domain Cupin_2 PF07883.6 EPE32572.1 - 0.012 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain JmjC PF02373.17 EPE32572.1 - 0.014 15.6 0.2 2.1 8.6 0.0 3.5 4 0 0 4 4 4 0 JmjC domain, hydroxylase FRG1 PF06229.7 EPE32572.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FRG1-like family RNA_capsid PF03035.9 EPE32573.1 - 0.079 12.7 0.2 0.079 12.7 0.1 1.5 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein zf-C2H2_4 PF13894.1 EPE32574.1 - 0.00049 20.2 8.4 0.024 14.9 0.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE32574.1 - 0.36 11.2 6.9 1.8 9.0 0.2 4.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.21 EPE32574.1 - 8.6 6.9 9.6 3.2 8.2 0.3 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type Use1 PF09753.4 EPE32575.1 - 1.7e-06 27.7 6.6 8.8e-06 25.3 4.5 2.1 1 1 0 1 1 1 1 Membrane fusion protein Use1 Ndc1_Nup PF09531.5 EPE32575.1 - 0.023 13.1 0.1 0.032 12.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4463 PF14703.1 EPE32575.1 - 0.078 13.5 1.2 0.078 13.5 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) DUF605 PF04652.11 EPE32575.1 - 0.11 11.8 6.8 0.14 11.5 4.7 1.2 1 0 0 1 1 1 0 Vta1 like Spc24 PF08286.6 EPE32575.1 - 1 9.0 7.8 0.064 12.9 1.4 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PTCB-BRCT PF12738.2 EPE32576.1 - 1e-06 28.4 0.2 2.6e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EPE32576.1 - 2.5e-06 27.5 0.1 7.1e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain SDA1 PF05285.7 EPE32576.1 - 0.57 9.4 14.1 1.1 8.5 9.8 1.3 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.7 EPE32576.1 - 0.72 8.1 14.3 1.3 7.2 9.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 EPE32576.1 - 0.92 8.5 12.9 1.7 7.5 9.0 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 EPE32576.1 - 1.2 7.1 7.4 1.7 6.5 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 EPE32576.1 - 3.7 6.1 15.6 6.9 5.2 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) IGPS PF00218.16 EPE32577.1 - 4.5e-97 324.0 0.5 1.6e-96 322.3 0.0 2.1 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EPE32577.1 - 2.1e-51 174.2 0.2 6e-48 163.0 0.2 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EPE32577.1 - 9.6e-49 165.4 0.0 1.7e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPE32577.1 - 4.1e-07 29.6 0.0 8.7e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EPE32577.1 - 0.0017 17.9 2.9 0.24 10.9 0.1 3.7 3 1 1 4 4 4 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 EPE32577.1 - 0.0052 16.0 0.1 0.027 13.7 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.9 EPE32577.1 - 0.0062 15.5 1.3 0.026 13.4 0.0 2.5 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase Nup188 PF10487.4 EPE32578.1 - 1.7e-37 128.9 0.0 3.6e-37 127.8 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DNA_pol_viral_N PF00242.12 EPE32579.1 - 6.7 5.6 24.9 10 5.0 17.3 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Abhydrolase_5 PF12695.2 EPE32580.1 - 6.2e-13 48.7 0.2 1.2e-12 47.8 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 EPE32580.1 - 3.8e-11 41.8 0.0 2.6e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 EPE32580.1 - 9.3e-11 42.0 0.2 1.4e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE32580.1 - 0.0027 17.5 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EPE32580.1 - 0.011 14.6 0.2 0.03 13.2 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EPE32580.1 - 0.058 12.9 0.1 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE32580.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1754 PF08555.5 EPE32581.1 - 9.8e-14 51.7 6.2 1.7e-13 50.9 4.3 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Mucin PF01456.12 EPE32582.1 - 2.1e-08 34.0 0.7 2.1e-08 34.0 0.5 5.1 1 1 3 4 4 4 1 Mucin-like glycoprotein Melibiase PF02065.13 EPE32583.1 - 6.3e-23 81.1 0.1 4.4e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 EPE32583.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 NmrA PF05368.8 EPE32584.1 - 2.1e-31 108.9 0.0 2.7e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE32584.1 - 7e-12 45.7 0.3 8.9e-12 45.3 0.2 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE32584.1 - 0.0086 14.8 0.0 0.015 13.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EPE32584.1 - 0.046 13.3 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 EPE32584.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Neural_ProG_Cyt PF06567.6 EPE32584.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain zf-Tim10_DDP PF02953.10 EPE32585.1 - 9.1e-20 69.7 2.6 1.5e-19 68.9 1.8 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RhoGAP PF00620.22 EPE32586.1 - 5.9e-38 129.8 0.0 1e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain O-FucT PF10250.4 EPE32587.1 - 4.2e-09 35.9 0.0 3.1e-06 26.5 0.0 2.7 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Clr5 PF14420.1 EPE32588.1 - 9.2e-19 67.0 7.6 2e-18 66.0 5.2 1.6 1 0 0 1 1 1 1 Clr5 domain AAA PF00004.24 EPE32588.1 - 3.1e-18 66.2 0.0 7.2e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE32588.1 - 0.0013 18.8 0.5 0.011 15.9 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE32588.1 - 0.035 13.8 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EPE32588.1 - 0.077 13.8 0.0 0.4 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 EPE32588.1 - 0.16 10.6 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_16 PF13191.1 EPE32588.1 - 0.17 11.8 0.6 0.61 10.0 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain zf-DHHC PF01529.15 EPE32589.1 - 1.3 8.3 5.1 0.85 8.9 1.7 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase ABC2_membrane_5 PF13346.1 EPE32589.1 - 3.4 6.8 17.6 0.46 9.7 0.2 2.7 3 0 0 3 3 3 0 ABC-2 family transporter protein DUF2534 PF10749.4 EPE32590.1 - 0.025 14.4 0.6 0.04 13.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) HET PF06985.6 EPE32591.1 - 1.3e-25 90.1 0.1 2.5e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lipase_GDSL PF00657.17 EPE32593.1 - 4e-07 30.0 0.0 5.6e-07 29.6 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EPE32593.1 - 4.5e-06 26.9 0.0 5.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family tRNA-synt_2b PF00587.20 EPE32594.1 - 1.2e-24 86.7 0.0 1.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EPE32594.1 - 2.5e-09 37.0 9.0 2.1e-08 34.1 6.2 2.2 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain RRF_GI PF12614.3 EPE32594.1 - 0.025 14.3 0.2 0.7 9.7 0.2 2.5 2 0 0 2 2 2 0 Ribosome recycling factor K-box PF01486.12 EPE32594.1 - 0.36 10.6 6.8 2.4 7.9 4.7 2.2 1 1 0 1 1 1 0 K-box region Actin PF00022.14 EPE32595.1 - 7.1e-20 70.7 0.1 5.8e-17 61.1 0.0 2.8 2 1 0 2 2 2 2 Actin XPG_I PF00867.13 EPE32596.1 - 1.9e-23 82.3 0.0 4.3e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EPE32596.1 - 2.2e-07 31.0 0.0 4.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EPE32596.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing CH PF00307.26 EPE32600.1 - 1.7e-11 44.1 0.1 3e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EPE32600.1 - 0.0016 18.0 0.1 0.0034 16.9 0.1 1.5 1 0 0 1 1 1 1 CAMSAP CH domain PI-PLC-X PF00388.14 EPE32601.1 - 3.4e-60 201.6 0.1 6.2e-60 200.8 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EPE32601.1 - 1.8e-39 134.3 0.2 5.2e-39 132.8 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EPE32601.1 - 5.1e-07 29.4 0.0 1.6e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 C2 domain EF-hand_5 PF13202.1 EPE32601.1 - 0.0014 17.9 0.9 0.0049 16.1 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_like PF09279.6 EPE32601.1 - 0.0014 18.5 0.6 0.0037 17.2 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.12 EPE32601.1 - 0.0039 16.7 0.0 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_7 PF13499.1 EPE32601.1 - 0.013 15.6 0.7 0.099 12.7 0.3 2.6 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 EPE32601.1 - 0.027 13.7 0.1 0.027 13.7 0.0 3.6 4 0 0 4 4 4 0 EF hand EF-hand_8 PF13833.1 EPE32601.1 - 0.028 14.0 0.4 0.13 11.9 0.3 2.2 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_10 PF14788.1 EPE32601.1 - 0.098 12.3 0.1 0.26 10.9 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EPE32601.1 - 0.11 12.4 0.2 0.11 12.4 0.1 3.6 4 0 0 4 4 4 0 EF-hand domain HATPase_c PF02518.21 EPE32603.1 - 1.1e-28 99.0 0.3 3.5e-28 97.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE32603.1 - 1.6e-20 73.1 0.0 4.2e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EPE32603.1 - 7.9e-20 70.6 0.3 2.8e-19 68.8 0.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 EPE32603.1 - 4.2e-12 46.7 0.0 1.1e-11 45.4 0.0 1.8 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.1 EPE32603.1 - 3.3e-11 43.5 0.0 1e-10 41.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain GAF PF01590.21 EPE32603.1 - 8.2e-10 39.0 0.0 1.9e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EPE32603.1 - 2.2e-09 36.8 0.0 4.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 EPE32603.1 - 1.1e-07 31.9 0.0 2.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.12 EPE32603.1 - 0.00013 21.1 0.0 0.0003 19.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.1 EPE32603.1 - 0.0054 16.6 8.8 0.17 11.8 0.2 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat ArgK PF03308.11 EPE32603.1 - 0.0087 14.8 0.0 0.021 13.6 0.0 1.5 1 0 0 1 1 1 1 ArgK protein HATPase_c_3 PF13589.1 EPE32603.1 - 0.04 13.5 0.1 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_8 PF13181.1 EPE32603.1 - 0.051 13.3 0.8 65 3.6 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat NAD_binding_8 PF13450.1 EPE32604.1 - 1.3e-08 34.7 0.0 3.3e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPE32604.1 - 8.6e-06 25.9 0.1 2e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EPE32604.1 - 0.002 17.2 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EPE32604.1 - 0.005 16.7 0.0 0.035 13.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE32604.1 - 0.0091 15.1 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EPE32604.1 - 0.022 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EPE32604.1 - 0.041 12.3 0.1 0.068 11.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EPE32604.1 - 0.042 13.6 0.3 0.72 9.6 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EPE32604.1 - 0.16 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain INO80_Ies4 PF08193.6 EPE32605.1 - 5.8e-66 222.6 20.4 5.8e-66 222.6 14.1 1.5 2 0 0 2 2 2 1 INO80 complex subunit Ies4 CLTH PF10607.4 EPE32606.1 - 9.1e-33 112.9 0.3 1.3e-32 112.5 0.2 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EPE32606.1 - 4.8e-22 78.3 0.0 8.9e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EPE32606.1 - 7.8e-05 22.3 0.7 0.00089 18.9 0.0 2.8 3 0 0 3 3 3 1 LisH HsbA PF12296.3 EPE32606.1 - 0.01 15.6 0.0 0.58 10.0 0.0 2.6 2 0 0 2 2 2 0 Hydrophobic surface binding protein A DUF387 PF04079.11 EPE32606.1 - 0.12 11.7 0.1 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) CHRD PF07452.7 EPE32607.1 - 0.00011 22.8 0.0 0.00023 21.7 0.0 1.5 1 1 0 1 1 1 1 CHRD domain GST_C_2 PF13410.1 EPE32608.1 - 7.1e-05 22.6 0.1 0.00013 21.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPE32608.1 - 0.0013 19.1 0.1 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2731 PF10806.3 EPE32608.1 - 0.0042 17.3 0.1 0.0098 16.1 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2731) Tom37 PF10568.4 EPE32608.1 - 0.022 15.0 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein DUF3717 PF12512.3 EPE32609.1 - 0.07 12.7 0.0 0.072 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) FTZ PF03867.9 EPE32610.1 - 0.13 11.5 9.7 0.13 11.4 6.7 1.0 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region SR-25 PF10500.4 EPE32610.1 - 0.39 10.1 10.9 0.49 9.8 7.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.4 EPE32610.1 - 1.8 7.3 11.3 2 7.1 7.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2217 PF10265.4 EPE32610.1 - 3.3 6.3 12.0 3.3 6.3 8.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 EPE32610.1 - 3.8 5.6 12.2 4 5.5 8.4 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1675 PF07897.6 EPE32610.1 - 3.8 7.2 10.4 4.2 7.1 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Senescence_reg PF04520.8 EPE32610.1 - 3.9 7.9 8.4 4.4 7.7 5.8 1.1 1 0 0 1 1 1 0 Senescence regulator KAR9 PF08580.5 EPE32610.1 - 4.5 5.4 12.6 5.3 5.1 8.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF605 PF04652.11 EPE32610.1 - 6.2 6.1 16.0 7.5 5.8 11.1 1.0 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EPE32610.1 - 7.2 6.3 14.4 7.8 6.2 10.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gag_spuma PF03276.9 EPE32610.1 - 7.6 4.7 12.9 8.3 4.6 8.9 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Peptidase_S64 PF08192.6 EPE32610.1 - 7.9 4.6 11.7 8.5 4.5 8.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 APH PF01636.18 EPE32611.1 - 4.4e-10 39.6 0.2 2.1e-09 37.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE32611.1 - 1.5e-06 27.9 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPE32611.1 - 0.00024 20.3 0.0 0.00032 19.9 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EPE32611.1 - 0.058 12.0 0.0 0.075 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RIO1 PF01163.17 EPE32611.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PSP1 PF04468.7 EPE32613.1 - 4.2e-30 103.5 0.9 6.8e-30 102.8 0.6 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.6 EPE32614.1 - 1.6e-27 94.9 0.0 4.3e-27 93.5 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EPE32614.1 - 2.8e-22 78.2 0.3 4.5e-22 77.5 0.2 1.3 1 0 0 1 1 1 1 NifU-like domain zf-HIT PF04438.11 EPE32615.1 - 4.6e-09 35.7 12.5 6.4e-09 35.3 8.7 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 EPE32615.1 - 0.0034 17.2 8.9 0.0056 16.5 6.2 1.3 1 0 0 1 1 1 1 MYND finger CIAPIN1 PF05093.8 EPE32615.1 - 0.0054 16.8 1.9 0.012 15.6 1.3 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis GRDB PF07355.7 EPE32615.1 - 0.071 12.0 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) zf-B_box PF00643.19 EPE32615.1 - 0.21 11.4 7.8 0.35 10.7 5.4 1.3 1 0 0 1 1 1 0 B-box zinc finger Tnp_zf-ribbon_2 PF13842.1 EPE32615.1 - 1.4 9.4 9.9 2.2 8.7 6.9 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon RasGEF PF00617.14 EPE32617.1 - 4.5e-44 150.4 0.1 8.2e-44 149.5 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EPE32617.1 - 1.6e-13 50.6 0.0 3.8e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EPE32617.1 - 2.5e-13 50.5 0.0 7.1e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 EPE32617.1 - 5.5e-07 29.1 0.0 1.8e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Ras family G-alpha PF00503.15 EPE32617.1 - 0.0078 14.9 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.22 EPE32617.1 - 0.029 14.6 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 EPE32617.1 - 0.029 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ribosomal_L15e PF00827.12 EPE32618.1 - 8.3e-91 302.7 11.2 9.4e-91 302.5 7.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 HECT PF00632.20 EPE32619.1 - 1e-74 251.5 0.0 1.4e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Suf PF05843.9 EPE32619.1 - 0.014 15.1 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) L51_S25_CI-B8 PF05047.11 EPE32620.1 - 5.7e-10 38.7 0.0 8.9e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MMR_HSR1 PF01926.18 EPE32621.1 - 4.5e-05 23.3 0.0 0.0003 20.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ank_2 PF12796.2 EPE32623.1 - 0.003 17.8 0.1 0.0096 16.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPE32623.1 - 0.028 14.6 0.0 0.32 11.3 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat EssA PF10661.4 EPE32623.1 - 0.62 9.7 5.6 0.27 10.9 0.6 2.1 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA zf-FPG_IleRS PF06827.9 EPE32624.1 - 0.0056 16.2 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-CSL PF05207.8 EPE32625.1 - 3.6e-16 58.3 0.3 5.9e-16 57.7 0.2 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EPE32625.1 - 4.3e-12 45.5 0.1 6.9e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain HMGL-like PF00682.14 EPE32626.1 - 9.5e-71 238.1 0.5 9.5e-71 238.1 0.3 1.7 2 0 0 2 2 2 1 HMGL-like Methyltransf_23 PF13489.1 EPE32627.1 - 4.3e-20 72.0 0.0 7.1e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE32627.1 - 1.8e-10 40.6 0.0 8e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE32627.1 - 1.7e-07 31.8 0.0 2.3e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE32627.1 - 1.8e-06 28.3 0.0 4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE32627.1 - 5.2e-05 23.6 0.0 0.00037 20.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE32627.1 - 0.00072 19.8 0.0 0.0037 17.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EPE32627.1 - 0.0047 16.0 0.0 0.009 15.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EPE32627.1 - 0.0077 15.7 0.0 0.057 12.8 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EPE32627.1 - 0.01 14.9 0.0 0.099 11.7 0.0 2.4 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EPE32627.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EPE32627.1 - 0.024 14.6 0.0 0.044 13.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain HTH_24 PF13412.1 EPE32627.1 - 0.041 13.2 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Methyltransf_4 PF02390.12 EPE32627.1 - 0.047 12.7 0.0 0.086 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 EPE32627.1 - 0.12 11.8 0.0 0.42 10.0 0.0 1.9 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EPE32627.1 - 0.13 11.5 0.0 0.43 9.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain HPP PF04982.8 EPE32628.1 - 2e-37 127.6 3.2 3.5e-37 126.8 2.2 1.4 1 0 0 1 1 1 1 HPP family HlyIII PF03006.15 EPE32629.1 - 2.3e-59 200.4 16.9 2.9e-59 200.1 11.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF373 PF04123.8 EPE32629.1 - 0.024 13.6 2.1 0.041 12.9 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) SPC12 PF06645.8 EPE32629.1 - 0.077 12.8 2.1 0.15 11.9 0.6 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) p450 PF00067.17 EPE32630.1 - 1.2e-74 251.5 0.0 1.4e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAGAT PF03982.8 EPE32631.1 - 1.2e-94 316.3 0.0 1.7e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EPE32631.1 - 0.0055 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Rer1 family zf-H2C2_2 PF13465.1 EPE32632.1 - 5.3e-16 58.0 21.3 1.4e-08 34.5 1.4 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EPE32632.1 - 2.8e-12 46.2 26.2 0.00027 21.1 4.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE32632.1 - 2.1e-09 37.0 22.2 0.004 17.3 3.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPE32632.1 - 6.5e-05 22.9 13.7 0.013 15.6 0.7 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 EPE32632.1 - 0.0018 18.2 3.8 1.5 8.9 0.1 3.4 3 0 0 3 3 3 1 zinc-finger zf-C2H2_6 PF13912.1 EPE32632.1 - 0.0041 16.9 13.5 0.35 10.8 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-CHCC PF10276.4 EPE32632.1 - 0.0041 16.9 5.8 0.38 10.6 0.4 3.3 3 0 0 3 3 3 1 Zinc-finger domain zf-Di19 PF05605.7 EPE32632.1 - 0.027 14.5 13.0 0.14 12.3 5.8 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding GAS PF13851.1 EPE32632.1 - 0.067 12.3 5.6 0.12 11.5 3.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EPE32632.1 - 0.11 12.8 5.1 0.28 11.5 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Kinesin-relat_1 PF12711.2 EPE32632.1 - 0.28 11.5 8.5 2.5 8.5 3.5 2.3 2 0 0 2 2 2 0 Kinesin motor DZR PF12773.2 EPE32632.1 - 0.45 10.3 6.4 6.4 6.6 4.4 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-CHY PF05495.7 EPE32632.1 - 1.2 9.3 8.5 2.8 8.1 5.9 1.6 1 0 0 1 1 1 0 CHY zinc finger zinc_ribbon_5 PF13719.1 EPE32632.1 - 2.3 7.8 5.8 15 5.2 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EPE32632.1 - 3.3 7.4 5.7 27 4.5 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EPE32632.1 - 3.3 7.7 8.8 20 5.2 2.3 3.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 EPE32632.1 - 3.5 7.8 14.4 4.8 7.3 1.1 3.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) NuA4 PF09340.5 EPE32632.1 - 7.6 6.2 7.6 27 4.5 0.0 3.2 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 Kinesin PF00225.18 EPE32634.1 - 5.3e-95 317.9 0.0 1e-94 316.9 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Stk19 PF10494.4 EPE32635.1 - 1.8e-76 256.8 0.0 2.1e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Homeobox PF00046.24 EPE32638.1 - 9.9e-13 47.5 6.1 3e-12 45.9 4.2 1.9 1 0 0 1 1 1 1 Homeobox domain Ras PF00071.17 EPE32639.1 - 2.9e-48 163.2 0.0 5.3e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE32639.1 - 2e-13 50.8 0.0 4.4e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE32639.1 - 4.6e-10 39.0 0.0 7.2e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EPE32639.1 - 0.0006 19.9 0.0 0.0061 16.7 0.0 2.6 2 1 0 2 2 2 1 RNA helicase PDZ_2 PF13180.1 EPE32639.1 - 0.0029 17.4 0.0 0.0094 15.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EPE32639.1 - 0.0035 17.4 0.0 0.0095 16.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Gtr1_RagA PF04670.7 EPE32639.1 - 0.0083 15.2 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 EPE32639.1 - 0.04 13.1 0.4 0.14 11.4 0.1 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 EPE32639.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EPE32639.1 - 0.13 12.4 0.1 0.48 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EPE32639.1 - 0.21 10.2 1.8 2.7 6.5 0.1 2.5 2 1 1 3 3 3 0 G-protein alpha subunit RhoGEF PF00621.15 EPE32640.1 - 3.1e-23 82.5 0.0 5.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Hap4_Hap_bind PF10297.4 EPE32641.1 - 0.029 14.2 1.2 0.057 13.2 0.8 1.5 1 0 0 1 1 1 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 CorA PF01544.13 EPE32642.1 - 0.0017 17.4 2.6 0.0021 17.1 0.8 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PolyA_pol PF01743.15 EPE32642.1 - 0.082 13.1 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Poly A polymerase head domain DUF3638 PF12340.3 EPE32644.1 - 6.8e-93 309.8 2.9 1.3e-92 308.9 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EPE32644.1 - 8.5e-15 53.5 0.1 2.2e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Pkinase PF00069.20 EPE32644.1 - 5.1e-12 45.4 0.0 1.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain p450 PF00067.17 EPE32645.1 - 9.2e-47 159.5 0.1 1.2e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2401 PF10287.4 EPE32646.1 - 1.3e-81 273.5 0.0 1.8e-81 273.1 0.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EPE32646.1 - 8.7e-25 86.6 0.0 2.4e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Topo_Zn_Ribbon PF08272.6 EPE32646.1 - 0.083 12.2 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like TRAP_alpha PF03896.11 EPE32647.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Atg14 PF10186.4 EPE32648.1 - 2.3e-76 256.6 0.0 2.9e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EPE32648.1 - 0.027 13.1 1.8 0.041 12.5 1.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AIP3 PF03915.8 EPE32648.1 - 0.066 12.1 2.9 0.1 11.4 2.0 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 TPR_MLP1_2 PF07926.7 EPE32648.1 - 0.18 11.5 4.0 0.4 10.4 2.5 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.7 EPE32648.1 - 1.8 8.7 8.5 4.1 7.6 3.8 2.3 1 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF3807 PF12720.2 EPE32650.1 - 3.4e-39 134.7 3.9 4.4e-39 134.4 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) GAGA_bind PF06217.7 EPE32650.1 - 0.0027 17.7 2.1 0.0035 17.3 1.4 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family zf-B_box PF00643.19 EPE32651.1 - 0.047 13.5 2.5 0.07 13.0 1.7 1.2 1 0 0 1 1 1 0 B-box zinc finger DUF605 PF04652.11 EPE32651.1 - 0.11 11.8 16.6 0.8 9.0 4.8 2.1 2 0 0 2 2 2 0 Vta1 like zf-C3HC4_2 PF13923.1 EPE32651.1 - 0.15 12.1 4.9 0.26 11.3 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4448 PF14610.1 EPE32652.1 - 9.1e-46 155.7 0.0 1.2e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SBP56 PF05694.6 EPE32652.1 - 0.025 13.0 0.0 0.039 12.4 0.0 1.2 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) RicinB_lectin_2 PF14200.1 EPE32657.1 - 0.00016 21.9 0.6 0.0071 16.7 0.1 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like SKG6 PF08693.5 EPE32657.1 - 0.0011 18.1 0.2 0.0011 18.1 0.1 1.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain FAP PF07174.6 EPE32657.1 - 0.016 14.5 4.1 0.027 13.8 2.8 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) VSP PF03302.8 EPE32657.1 - 0.025 13.2 0.2 0.033 12.8 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF829 PF05705.9 EPE32659.1 - 5.9e-42 144.0 0.0 6.9e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EPE32659.1 - 0.00011 22.1 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE32659.1 - 0.0061 16.3 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family GATA PF00320.22 EPE32661.1 - 3.9e-13 48.5 3.9 8.8e-13 47.3 2.7 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1295 PF06966.7 EPE32663.1 - 8.9e-54 182.2 0.2 1.2e-53 181.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) GFA PF04828.9 EPE32663.1 - 3.4e-06 26.9 0.2 7.1e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Steroid_dh PF02544.11 EPE32663.1 - 1.3e-05 25.0 1.7 7.7e-05 22.5 0.1 2.7 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EPE32663.1 - 2e-05 24.6 0.0 0.00025 21.0 0.0 2.6 1 1 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 EPE32663.1 - 3.1e-05 24.0 0.0 6.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Nnf1 PF03980.9 EPE32663.1 - 0.0035 17.3 1.6 0.009 15.9 1.1 1.6 1 0 0 1 1 1 1 Nnf1 EmrE PF13536.1 EPE32663.1 - 0.011 15.9 2.6 0.011 15.9 1.8 2.4 3 0 0 3 3 3 0 Multidrug resistance efflux transporter IncA PF04156.9 EPE32663.1 - 5 6.6 8.4 56 3.2 4.7 2.5 2 0 0 2 2 2 0 IncA protein RINGv PF12906.2 EPE32664.1 - 2.6e-16 59.3 9.4 2.6e-16 59.3 6.5 1.7 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EPE32664.1 - 0.21 11.4 8.4 0.42 10.4 5.8 1.5 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 EPE32664.1 - 0.22 11.3 3.3 0.52 10.1 2.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EPE32664.1 - 3.7 7.2 6.1 7.6 6.2 4.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain KRE9 PF05390.6 EPE32665.1 - 2.5e-13 50.3 6.3 2.5e-13 50.3 4.3 2.1 3 0 0 3 3 3 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 EPE32665.1 - 3.3e-10 40.3 0.9 7.1e-10 39.2 0.1 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PALP PF00291.20 EPE32666.1 - 4.2e-59 200.2 0.1 5.3e-59 199.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EPE32666.1 - 1.5e-08 34.2 0.0 2e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 CBS domain SRPRB PF09439.5 EPE32667.1 - 1.1e-33 116.0 0.0 8.5e-33 113.0 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPE32667.1 - 3.2e-06 27.0 0.0 6.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EPE32667.1 - 1.4e-05 25.2 0.4 2.2e-05 24.5 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain Arf PF00025.16 EPE32667.1 - 1.5e-05 24.3 0.0 0.00094 18.4 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.1 EPE32667.1 - 5e-05 23.4 0.1 0.00026 21.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EPE32667.1 - 7.8e-05 22.1 0.0 0.00035 20.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPE32667.1 - 0.00015 20.9 0.0 0.00021 20.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EPE32667.1 - 0.00033 20.2 0.0 0.069 12.6 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 EPE32667.1 - 0.0013 19.2 0.0 0.011 16.2 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EPE32667.1 - 0.0053 15.9 0.2 0.015 14.4 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EPE32667.1 - 0.0068 16.7 0.2 0.013 15.7 0.1 1.7 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EPE32667.1 - 0.0095 15.4 0.2 0.024 14.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.14 EPE32667.1 - 0.012 15.0 0.2 1.3 8.4 0.2 2.5 2 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EPE32667.1 - 0.014 14.4 0.0 0.044 12.7 0.0 1.7 2 0 0 2 2 2 0 Septin AAA PF00004.24 EPE32667.1 - 0.02 15.0 0.4 0.17 12.0 0.3 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 EPE32667.1 - 0.021 14.7 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPE32667.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EPE32667.1 - 0.031 13.7 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EPE32667.1 - 0.049 13.9 0.0 0.096 12.9 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 EPE32667.1 - 0.051 14.3 0.2 0.086 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EPE32667.1 - 0.06 12.0 0.0 3.8 6.1 0.2 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Ras PF00071.17 EPE32667.1 - 0.063 12.6 0.0 0.55 9.5 0.0 2.2 2 1 0 2 2 2 0 Ras family SRP54 PF00448.17 EPE32667.1 - 0.078 12.4 0.1 9.6 5.5 0.1 2.3 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EPE32667.1 - 0.12 12.2 0.6 0.57 10.0 0.3 1.8 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EPE32667.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 EPE32668.1 - 8.9e-43 144.5 0.0 4.4e-17 62.1 0.0 3.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPE32668.1 - 1.7e-36 122.1 2.4 2e-08 33.6 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EPE32668.1 - 8e-27 92.6 3.6 1.8e-07 31.1 0.0 5.0 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE32668.1 - 5.8e-23 80.8 1.9 3.6e-06 27.3 0.1 3.9 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE32668.1 - 4.5e-22 75.9 3.2 7.8e-07 28.7 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat zf-DHHC PF01529.15 EPE32668.1 - 8.9e-05 21.9 7.1 0.015 14.7 0.8 3.1 2 1 1 3 3 3 2 DHHC palmitoyltransferase ATP-synt_C PF00137.16 EPE32669.1 - 2.3e-15 56.2 12.5 4.2e-15 55.3 8.7 1.5 1 0 0 1 1 1 1 ATP synthase subunit C DUF1469 PF07332.6 EPE32669.1 - 0.26 11.0 5.2 0.57 9.9 3.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) EHN PF06441.7 EPE32670.1 - 5.1e-27 94.0 0.9 1.4e-25 89.4 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EPE32670.1 - 3.3e-08 33.6 0.1 6.3e-08 32.7 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE32670.1 - 0.00036 20.1 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M14 PF00246.19 EPE32671.1 - 8.6e-70 235.5 0.0 1.1e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.15 EPE32672.1 - 4.5e-38 130.8 0.0 1.2e-37 129.4 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EPE32672.1 - 6.2e-06 26.3 0.1 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EPE32672.1 - 4.2e-05 23.7 0.1 9.5e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 PH domain Zn_clus PF00172.13 EPE32673.1 - 1.9e-07 30.8 8.3 1.9e-07 30.8 5.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE32673.1 - 0.002 16.8 0.3 0.0025 16.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EPE32674.1 - 6e-07 29.5 0.1 1.2e-06 28.5 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE32674.1 - 4.5e-05 23.3 0.0 6.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPE32674.1 - 0.0018 17.7 0.0 0.0037 16.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPE32674.1 - 0.0054 15.6 0.0 0.0074 15.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Shikimate_DH PF01488.15 EPE32674.1 - 0.014 15.4 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EPE32674.1 - 0.016 14.8 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PsbI PF02532.9 EPE32677.1 - 0.04 13.5 0.4 0.08 12.5 0.3 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Endonuclease_NS PF01223.18 EPE32678.1 - 4.6e-62 209.3 0.0 5.8e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease WD40 PF00400.27 EPE32679.1 - 7.9e-45 149.1 18.4 3.9e-08 32.8 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EPE32679.1 - 0.047 12.4 0.0 0.32 9.7 0.1 2.2 2 1 0 2 2 2 0 Nup133 N terminal like eIF2A PF08662.6 EPE32679.1 - 0.082 12.6 0.1 3.2 7.4 0.0 2.6 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A MBOAT PF03062.14 EPE32680.1 - 5.2e-22 78.3 13.0 5.2e-22 78.3 9.0 2.0 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EPE32680.1 - 0.0062 16.5 1.7 0.021 14.8 1.2 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RNase_PH PF01138.16 EPE32681.1 - 5.8e-22 78.4 0.0 1e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EPE32681.1 - 3.4e-05 23.6 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 EPE32682.1 - 6e-88 294.6 16.5 6.8e-88 294.4 11.5 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2890 PF11081.3 EPE32682.1 - 0.058 13.4 15.0 0.11 12.4 10.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) GEMIN8 PF15348.1 EPE32682.1 - 0.082 12.9 8.6 0.096 12.7 5.9 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DDHD PF02862.12 EPE32682.1 - 0.45 10.2 3.1 0.52 10.0 2.2 1.2 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.10 EPE32682.1 - 1.1 7.8 7.5 1.2 7.6 5.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 EPE32682.1 - 1.7 6.5 17.9 2.1 6.3 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 EPE32682.1 - 2.5 7.4 11.7 3.5 7.0 8.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.7 EPE32682.1 - 3 7.6 11.0 4 7.2 7.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 EPE32682.1 - 3.4 5.4 22.8 3.7 5.3 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1151 PF06625.6 EPE32682.1 - 3.6 7.3 19.1 1.8 8.3 11.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) APG6 PF04111.7 EPE32682.1 - 3.9 6.4 12.0 5.3 5.9 8.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Tom37_C PF11801.3 EPE32682.1 - 4.3 7.1 6.9 5.9 6.7 4.8 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Atg14 PF10186.4 EPE32682.1 - 7.1 5.4 7.9 11 4.8 5.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RNA_polI_A34 PF08208.6 EPE32682.1 - 7.6 6.1 14.2 11 5.6 9.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YqfQ PF14181.1 EPE32682.1 - 7.7 6.5 9.1 14 5.6 6.3 1.4 1 0 0 1 1 1 0 YqfQ-like protein Tmemb_170 PF10190.4 EPE32685.1 - 4.5e-05 23.4 10.0 5.8e-05 23.1 6.9 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF4311 PF14188.1 EPE32685.1 - 0.86 9.0 6.1 6.2 6.2 4.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4311) Hexapep_2 PF14602.1 EPE32686.1 - 3.1e-12 45.8 11.1 3.1e-11 42.6 3.0 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EPE32686.1 - 4.3e-12 45.8 0.1 7.2e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 EPE32686.1 - 5.2e-12 44.7 8.1 3.3e-11 42.1 2.3 2.9 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) ICMT PF04140.9 EPE32687.1 - 3.2e-25 88.1 0.1 5.2e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EPE32687.1 - 4e-13 49.3 1.0 9.3e-13 48.2 0.7 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 EPE32687.1 - 0.0025 17.1 0.1 0.0035 16.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 EPE32687.1 - 0.04 13.2 3.6 0.081 12.2 2.4 1.8 1 1 0 1 1 1 0 NnrU protein Zip PF02535.17 EPE32688.1 - 4.9e-20 71.7 13.4 1.2e-19 70.4 9.3 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Tat PF00539.13 EPE32691.1 - 0.035 13.7 0.7 0.067 12.8 0.4 1.5 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) DUF2524 PF10732.4 EPE32691.1 - 0.057 13.5 0.1 0.066 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Lipase_GDSL_2 PF13472.1 EPE32692.1 - 2.4e-22 79.9 0.0 3.2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE32692.1 - 1.3e-20 74.2 0.0 1.5e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EPE32692.1 - 0.0055 16.4 0.0 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family EIIA-man PF03610.11 EPE32692.1 - 0.035 14.1 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 PTS system fructose IIA component ALF PF03752.8 EPE32692.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Short repeats of unknown function Voltage_CLC PF00654.15 EPE32693.1 - 1.4e-94 317.0 21.0 1.4e-94 317.0 14.6 1.8 2 1 0 2 2 2 1 Voltage gated chloride channel DUF4235 PF14019.1 EPE32693.1 - 0.17 11.7 2.5 1.4 8.8 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) Lectin_leg-like PF03388.8 EPE32694.1 - 1.4e-64 217.4 0.0 2.2e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EPE32694.1 - 0.011 15.0 0.0 0.99 8.7 0.0 2.2 2 0 0 2 2 2 0 Legume lectin domain zf-Tim10_DDP PF02953.10 EPE32695.1 - 1.4e-23 81.9 1.7 1.7e-23 81.6 1.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF4372 PF14294.1 EPE32695.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4372) DUF2040 PF09745.4 EPE32696.1 - 1.1e-38 131.8 23.0 1.1e-38 131.8 15.9 3.3 2 1 1 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) OmpH PF03938.9 EPE32697.1 - 0.013 15.4 1.3 0.017 15.0 0.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.20 EPE32698.1 - 1.5e-69 234.0 0.0 2e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE32698.1 - 1.4e-38 132.4 0.0 2.4e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE32698.1 - 8.4e-08 31.5 0.0 2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Rad21_Rec8 PF04824.11 EPE32698.1 - 0.014 14.5 0.2 0.041 13.0 0.2 1.8 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein APH PF01636.18 EPE32698.1 - 0.018 14.8 0.2 0.057 13.1 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EPE32698.1 - 0.046 12.7 0.0 0.1 11.6 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HAUS-augmin3 PF14932.1 EPE32699.1 - 0.0062 15.7 15.1 0.0062 15.7 10.5 2.9 1 1 2 3 3 3 1 HAUS augmin-like complex subunit 3 DDE_Tnp_IS1595 PF12762.2 EPE32699.1 - 0.051 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 ISXO2-like transposase domain DUF3287 PF11690.3 EPE32699.1 - 0.057 13.4 2.3 0.15 12.1 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) LrgB PF04172.11 EPE32700.1 - 1.5e-26 92.8 9.4 2e-25 89.2 3.5 3.0 3 0 0 3 3 3 2 LrgB-like family LrgA PF03788.9 EPE32700.1 - 0.0035 16.9 6.9 0.019 14.6 4.8 2.4 1 0 0 1 1 1 1 LrgA family Rotamase PF00639.16 EPE32701.1 - 4.7e-20 72.1 0.0 7.1e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EPE32701.1 - 2.2e-14 53.7 0.0 2.8e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EPE32701.1 - 1.4e-07 31.2 0.4 2.9e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EPE32701.1 - 2.6e-05 24.8 0.0 3.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.18 EPE32701.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 MAM domain ADH_N PF08240.7 EPE32702.1 - 7.6e-10 38.5 0.0 2.9e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE32702.1 - 1.8e-06 27.5 0.1 3.3e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RNA_POL_M_15KD PF02150.11 EPE32703.1 - 2.4e-11 43.1 2.0 2.4e-11 43.1 1.4 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit GFA PF04828.9 EPE32703.1 - 0.0022 17.9 2.7 0.19 11.6 0.1 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EPE32703.1 - 0.026 14.3 2.9 0.026 14.3 2.0 1.9 2 0 0 2 2 2 0 Double zinc ribbon IBR PF01485.16 EPE32703.1 - 0.32 10.8 3.7 1 9.2 1.3 2.1 2 0 0 2 2 2 0 IBR domain zf-C2HC5 PF06221.8 EPE32703.1 - 0.87 9.3 8.8 1.3 8.8 0.3 2.9 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type FYVE PF01363.16 EPE32703.1 - 1.3 9.0 6.5 2.5 8.0 1.5 2.3 2 0 0 2 2 2 0 FYVE zinc finger SET PF00856.23 EPE32704.1 - 3.1e-08 34.0 4.2 3.3e-07 30.7 0.0 3.3 3 2 0 3 3 3 1 SET domain KilA-N PF04383.8 EPE32706.1 - 0.00034 20.1 0.0 0.0087 15.6 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain BTB PF00651.26 EPE32707.1 - 0.00048 20.1 0.0 0.0019 18.1 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain PAP2_3 PF14378.1 EPE32708.1 - 3.4e-20 72.3 17.7 6.8e-16 58.3 3.1 2.6 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.16 EPE32708.1 - 0.048 13.3 6.6 0.064 12.9 3.4 1.9 1 1 0 1 1 1 0 PAP2 superfamily PAP2_C PF14360.1 EPE32708.1 - 0.054 13.7 0.4 0.054 13.7 0.3 3.3 3 1 1 4 4 4 0 PAP2 superfamily C-terminal RtcB PF01139.12 EPE32708.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB Patatin PF01734.17 EPE32709.1 - 4.6e-27 95.2 0.0 2.5e-26 92.8 0.0 2.2 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4 PF00097.20 EPE32709.1 - 0.0067 16.0 6.1 0.014 15.0 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE32709.1 - 0.039 13.9 6.5 0.1 12.6 4.4 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE32709.1 - 0.07 12.9 6.8 0.15 11.8 4.7 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EPE32709.1 - 0.25 11.1 6.5 0.53 10.0 4.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain ABC_tran PF00005.22 EPE32710.1 - 6.5e-05 23.2 0.0 0.00017 21.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EPE32710.1 - 0.0071 16.3 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain zf-B_box PF00643.19 EPE32710.1 - 0.0096 15.7 5.5 0.017 15.0 3.8 1.3 1 0 0 1 1 1 1 B-box zinc finger DUF258 PF03193.11 EPE32710.1 - 0.01 15.0 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPE32710.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EPE32710.1 - 0.013 15.3 0.3 0.032 14.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EPE32710.1 - 0.016 15.1 0.3 0.077 12.9 0.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EPE32710.1 - 0.038 13.5 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EPE32710.1 - 0.075 13.3 0.9 0.13 12.5 0.2 1.7 2 1 0 2 2 1 0 AAA domain AAA_10 PF12846.2 EPE32710.1 - 0.099 12.0 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 EPE32710.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP72 PF08492.7 EPE32711.1 - 2.9e-12 46.7 8.1 2.9e-12 46.7 5.6 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 EPE32711.1 - 0.00044 20.3 7.7 0.015 15.3 0.3 4.0 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 SPO22 PF08631.5 EPE32711.1 - 0.019 14.0 0.0 0.23 10.4 0.0 2.4 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 EPE32711.1 - 0.059 13.7 17.7 0.34 11.2 0.0 6.5 5 2 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPE32711.1 - 0.075 12.9 12.4 33 4.7 0.6 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPE32711.1 - 0.21 11.5 7.8 0.97 9.4 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPE32711.1 - 0.29 11.8 12.6 3 8.6 0.2 4.5 5 1 1 6 6 6 0 Tetratricopeptide repeat Glyco_hydro_16 PF00722.16 EPE32712.1 - 0.0019 17.4 1.3 0.042 13.1 0.9 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 EPE32713.1 - 6.2e-18 64.6 35.5 6.2e-18 64.6 24.6 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily N-Term_TEN PF11474.3 EPE32714.1 - 0.068 12.5 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Telomerase reverse transcriptase TEN domain Chitin_bind_3 PF03067.10 EPE32715.1 - 3.2e-07 30.8 0.4 4.4e-07 30.3 0.3 1.2 1 0 0 1 1 1 1 Chitin binding domain Glyco_hydro_10 PF00331.15 EPE32717.1 - 3.5e-94 315.4 0.4 4e-94 315.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Amidoligase_2 PF12224.3 EPE32718.1 - 6.2e-33 114.4 0.0 9.3e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme Sugar_tr PF00083.19 EPE32719.1 - 7e-81 272.0 21.0 8.1e-81 271.8 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE32719.1 - 3e-16 59.0 30.5 1.5e-10 40.3 4.5 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily HET PF06985.6 EPE32720.1 - 2.8e-21 76.1 8.7 5.2e-19 68.7 6.1 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF924 PF06041.6 EPE32721.1 - 2.2e-41 141.6 0.0 2.7e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) HSP90 PF00183.13 EPE32724.1 - 2.5e-253 841.2 33.0 3.1e-253 841.0 22.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EPE32724.1 - 7.5e-12 45.0 0.2 7.5e-12 45.0 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EPE32724.1 - 8.8e-12 44.7 0.1 1.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EPE32724.1 - 0.024 14.4 2.0 0.031 14.0 0.2 2.1 2 0 0 2 2 2 0 Tumour suppressor protein DUF1676 PF07898.8 EPE32724.1 - 0.15 12.3 0.2 0.15 12.3 0.1 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF1676) Tom37_C PF11801.3 EPE32724.1 - 4.8 7.0 8.9 11 5.8 3.1 2.6 2 0 0 2 2 2 0 Tom37 C-terminal domain Tetraspannin PF00335.15 EPE32727.1 - 0.032 13.4 6.1 0.072 12.3 4.2 1.5 1 1 0 1 1 1 0 Tetraspanin family DUF2207 PF09972.4 EPE32727.1 - 0.056 12.0 4.2 0.81 8.1 0.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF1361 PF07099.6 EPE32727.1 - 0.079 12.7 2.4 0.19 11.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1361) VD10_N PF08476.5 EPE32727.1 - 0.1 12.1 0.3 0.51 9.8 0.0 2.0 2 0 0 2 2 2 0 Viral D10 N-terminal DUF1705 PF08019.7 EPE32727.1 - 0.32 10.4 2.8 2 7.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) ABC2_membrane_3 PF12698.2 EPE32727.1 - 1 8.3 5.1 4.5 6.2 4.1 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Lipase_GDSL_2 PF13472.1 EPE32729.1 - 5.2e-17 62.5 0.9 5.2e-17 62.5 0.6 1.9 2 1 1 3 3 3 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE32729.1 - 2.8e-14 53.5 0.4 1.2e-13 51.4 0.3 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Baseplate_J PF04865.9 EPE32729.1 - 0.004 16.5 0.5 0.02 14.2 0.1 2.1 2 1 0 2 2 2 1 Baseplate J-like protein Peptidase_S8 PF00082.17 EPE32730.1 - 1.5e-47 162.1 21.6 1.9e-47 161.7 15.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EPE32730.1 - 6.7e-12 45.8 0.8 1.5e-11 44.6 0.6 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Septin PF00735.13 EPE32731.1 - 1e-23 83.8 0.1 9.2e-23 80.6 0.1 2.0 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EPE32731.1 - 3.7e-06 26.8 0.0 9.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPE32731.1 - 0.0002 21.8 0.1 0.00052 20.4 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EPE32731.1 - 0.0003 20.8 0.7 0.002 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 EPE32731.1 - 0.00066 19.9 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EPE32731.1 - 0.0027 16.9 0.0 0.0076 15.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EPE32731.1 - 0.0058 16.0 0.0 0.023 14.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EPE32731.1 - 0.014 15.2 0.0 0.042 13.6 0.0 1.8 1 0 0 1 1 1 0 Dynamin family AAA_24 PF13479.1 EPE32731.1 - 0.015 14.8 0.0 0.038 13.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 EPE32731.1 - 0.02 14.4 0.0 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EPE32731.1 - 0.026 14.2 0.1 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EPE32731.1 - 0.033 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EPE32731.1 - 0.074 12.7 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.12 EPE32731.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MCM PF00493.18 EPE32731.1 - 0.096 11.4 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_22 PF13401.1 EPE32731.1 - 0.11 12.5 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EPE32731.1 - 0.14 11.6 0.1 0.32 10.5 0.1 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Pkinase PF00069.20 EPE32732.1 - 1.5e-76 256.9 0.0 1.7e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE32732.1 - 1.7e-35 122.3 0.0 2.2e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPE32732.1 - 0.029 13.4 0.1 0.051 12.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE32732.1 - 0.03 14.0 0.1 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EPE32732.1 - 0.049 12.5 0.1 0.26 10.1 0.0 2.0 2 1 0 2 2 2 0 Kinase-like AAA PF00004.24 EPE32733.1 - 9.4e-18 64.6 0.0 2.3e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE32733.1 - 1.4e-05 25.9 0.0 0.00011 23.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EPE32733.1 - 0.00078 19.5 0.0 0.0043 17.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EPE32733.1 - 0.0095 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EPE32733.1 - 0.015 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EPE32733.1 - 0.016 14.2 0.1 0.27 10.2 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPE32733.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Methyltransf_11 PF08241.7 EPE32734.1 - 0.16 12.5 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Xan_ur_permease PF00860.15 EPE32735.1 - 5.9e-32 110.6 31.1 1.5e-31 109.3 21.5 1.6 1 1 0 1 1 1 1 Permease family HLH PF00010.21 EPE32737.1 - 7.7e-12 44.7 0.3 1.4e-11 43.9 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HAP1_N PF04849.8 EPE32737.1 - 0.0068 15.4 0.1 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region PAF-AH_p_II PF03403.8 EPE32738.1 - 1.3e-17 63.2 0.0 5.4e-09 34.8 0.0 2.3 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EPE32738.1 - 8.7e-14 51.4 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE32738.1 - 8.7e-10 38.8 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EPE32738.1 - 1.8e-07 30.3 0.0 8.6e-06 24.8 0.0 2.1 1 1 0 2 2 2 1 Chlorophyllase enzyme Lipase_3 PF01764.20 EPE32738.1 - 4.2e-06 26.4 0.0 9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.6 EPE32738.1 - 0.00095 18.0 0.6 0.0064 15.3 0.2 2.2 2 1 0 2 2 2 1 Chlorophyllase PGAP1 PF07819.8 EPE32738.1 - 0.0026 17.4 0.0 0.0098 15.5 0.0 1.9 1 1 0 1 1 1 1 PGAP1-like protein Lipase PF00151.14 EPE32738.1 - 0.024 13.8 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Lipase Abhydrolase_1 PF00561.15 EPE32738.1 - 0.026 14.0 0.1 0.079 12.4 0.1 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 EPE32738.1 - 0.11 10.9 0.0 0.16 10.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EPE32738.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2974 PF11187.3 EPE32738.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AA_permease_2 PF13520.1 EPE32742.1 - 1e-51 175.8 52.7 1.3e-51 175.5 36.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE32742.1 - 2.5e-19 68.9 44.5 3.2e-19 68.6 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease SecE PF00584.15 EPE32742.1 - 1.7 8.2 7.4 0.99 9.0 1.2 3.1 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Fungal_trans_2 PF11951.3 EPE32744.1 - 6.1e-09 34.9 0.5 3.9e-08 32.3 0.4 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain SAP PF02037.22 EPE32746.1 - 2.8e-14 52.2 0.0 6.3e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 SAP domain PorB PF11565.3 EPE32746.1 - 0.065 13.4 0.3 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 Alpha helical Porin B Methyltransf_11 PF08241.7 EPE32747.1 - 0.001 19.5 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_6 PF08030.7 EPE32748.1 - 1.1e-05 25.3 0.1 0.00059 19.7 0.1 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EPE32748.1 - 3.7e-05 24.2 0.0 0.00015 22.2 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EPE32748.1 - 0.0093 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain HET PF06985.6 EPE32750.1 - 2.4e-31 108.7 0.1 3.7e-23 82.2 0.1 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Syndecan PF01034.15 EPE32751.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 EPE32751.1 - 0.04 14.3 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.8 EPE32751.1 - 0.07 11.7 0.4 0.091 11.3 0.3 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF1191 PF06697.7 EPE32751.1 - 0.084 11.6 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 EPE32751.1 - 0.15 11.4 1.6 0.25 10.6 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Lamp PF01299.12 EPE32751.1 - 3.3 6.7 9.5 0.13 11.4 0.9 2.1 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) DUF2613 PF11021.3 EPE32751.1 - 9.3 6.0 8.8 1.2 8.9 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) p450 PF00067.17 EPE32753.1 - 9.4e-54 182.6 0.0 1.2e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 EPE32754.1 - 3.4e-32 111.5 0.3 5.3e-32 110.8 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dicty_CAR PF05462.6 EPE32755.1 - 7.1e-14 51.4 6.0 7.1e-14 51.4 4.2 1.4 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EPE32755.1 - 6.4e-06 25.8 7.3 1.2e-05 24.9 5.0 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DnaJ PF00226.26 EPE32758.1 - 1.2e-20 72.9 2.1 2.3e-20 72.0 1.4 1.5 1 0 0 1 1 1 1 DnaJ domain Laminin_G_3 PF13385.1 EPE32759.1 - 3.5e-20 72.8 3.8 1.3e-19 70.9 0.1 2.6 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 EPE32759.1 - 5.1e-10 39.4 0.0 1.3e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Laminin G domain Ricin_B_lectin PF00652.17 EPE32759.1 - 1.2e-08 35.0 3.3 3.9e-05 23.6 0.1 2.9 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain PLAT PF01477.18 EPE32759.1 - 1.9e-06 28.2 0.0 6.7e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 PLAT/LH2 domain Laminin_G_1 PF00054.18 EPE32759.1 - 0.00064 19.7 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain ATS3 PF06232.6 EPE32759.1 - 0.0025 17.4 0.0 0.024 14.2 0.0 2.2 2 0 0 2 2 2 1 Embryo-specific protein 3, (ATS3) HTH_7 PF02796.10 EPE32759.1 - 0.027 14.3 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase PA-IIL PF07472.6 EPE32760.1 - 0.00012 22.2 4.2 0.0011 19.0 2.9 2.0 1 1 0 1 1 1 1 Fucose-binding lectin II (PA-IIL) COesterase PF00135.23 EPE32761.1 - 6.5e-79 266.0 1.1 1.6e-78 264.7 0.8 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EPE32761.1 - 2.5e-05 23.6 0.1 4.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EPE32761.1 - 0.021 14.4 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ceramidase_alk PF04734.8 EPE32763.1 - 4.2e-09 34.8 0.2 5.3e-09 34.5 0.1 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase DUF3813 PF12758.2 EPE32763.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) GPI-anchored PF10342.4 EPE32764.1 - 3.6e-11 43.3 0.3 3.6e-11 43.3 0.2 1.7 1 1 1 2 2 2 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Zn_clus PF00172.13 EPE32765.1 - 2.7e-09 36.7 9.4 6.3e-09 35.6 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rhabdo_glycop PF00974.13 EPE32766.1 - 0.13 10.4 0.1 0.21 9.8 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Adaptin_N PF01602.15 EPE32767.1 - 7.1e-141 470.1 1.7 8.5e-141 469.8 1.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EPE32767.1 - 2.5e-21 76.1 0.1 7e-21 74.6 0.1 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EPE32767.1 - 3.6e-06 27.1 1.7 0.035 14.3 0.0 3.9 4 2 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EPE32767.1 - 0.0016 18.3 1.3 13 6.1 0.0 4.8 4 1 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EPE32767.1 - 0.0029 17.4 3.4 0.057 13.2 1.3 3.3 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 EPE32767.1 - 0.0063 16.1 0.4 0.035 13.7 0.0 2.3 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.1 EPE32767.1 - 0.007 16.8 1.2 11 6.7 0.0 4.4 3 1 0 4 4 4 1 HEAT-like repeat MBOAT PF03062.14 EPE32768.1 - 2.4e-31 109.0 26.2 4.6e-30 104.8 18.2 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family TPR_11 PF13414.1 EPE32773.1 - 2.7e-14 52.5 0.4 6.1e-14 51.4 0.2 1.6 1 0 0 1 1 1 1 TPR repeat DUF4470 PF14737.1 EPE32773.1 - 4.2e-11 42.4 0.0 1.2e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.12 EPE32773.1 - 1e-07 31.3 0.1 1.9e-05 24.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPE32773.1 - 4.5e-05 23.3 0.2 0.00011 22.0 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EPE32773.1 - 0.00028 20.8 0.2 0.0022 18.0 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPE32773.1 - 0.00035 20.8 0.2 0.00074 19.8 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPE32773.1 - 0.0061 17.2 0.3 0.016 15.8 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPE32773.1 - 0.0075 15.8 0.3 0.046 13.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE32773.1 - 0.02 15.4 0.8 1.2 9.9 0.0 3.0 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPE32773.1 - 0.055 13.4 0.6 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RVT_N PF13655.1 EPE32773.1 - 0.09 12.8 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of reverse transcriptase DNA_primase_lrg PF04104.9 EPE32774.1 - 3e-79 265.9 0.0 4.7e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Seryl_tRNA_N PF02403.17 EPE32775.1 - 6.6 6.7 26.3 0.63 10.0 5.6 3.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain 4HBT_2 PF13279.1 EPE32776.1 - 2.3e-21 76.4 0.1 3.1e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EPE32776.1 - 0.0073 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily ERM PF00769.14 EPE32776.1 - 0.062 12.8 1.7 0.089 12.3 1.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family PP1c_bdg PF10488.4 EPE32776.1 - 0.52 9.4 5.5 0.27 10.3 1.3 1.9 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region Complex1_LYR_2 PF13233.1 EPE32777.1 - 2.4e-05 24.7 0.0 2.6e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EPE32777.1 - 0.00059 19.9 0.1 0.00081 19.5 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EPE32777.1 - 0.001 18.8 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Methyltransf_25 PF13649.1 EPE32778.1 - 6.1e-09 36.1 0.0 1.2e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE32778.1 - 1.3e-08 35.1 0.0 3.1e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE32778.1 - 1e-07 31.8 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE32778.1 - 1.8e-07 31.1 0.0 2.7e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE32778.1 - 4.3e-07 30.5 0.0 1.3e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE32778.1 - 1.1e-05 25.0 0.0 3e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE32778.1 - 2.6e-05 24.6 0.0 5.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE32778.1 - 0.0011 18.1 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EPE32778.1 - 0.011 15.3 0.0 0.088 12.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EPE32778.1 - 0.017 14.5 0.0 0.045 13.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Exo_endo_phos PF03372.18 EPE32779.1 - 2.1e-19 70.4 0.8 3.3e-19 69.7 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EPE32779.1 - 1e-10 40.9 0.5 3.3e-05 23.3 0.1 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE32779.1 - 9.3e-06 25.3 4.1 0.00026 20.6 0.3 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EPE32779.1 - 9.3e-05 21.9 0.1 2 8.7 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EPE32779.1 - 0.0012 18.6 1.0 39 5.0 0.0 4.3 4 0 0 4 4 4 0 Leucine rich repeat Glyco_hydro_18 PF00704.23 EPE32780.1 - 7.5e-14 51.9 0.3 1.4e-12 47.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 DUF1272 PF06906.6 EPE32781.1 - 0.022 14.6 0.3 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Presenilin PF01080.12 EPE32781.1 - 0.48 9.2 1.7 0.47 9.2 1.2 1.1 1 0 0 1 1 1 0 Presenilin zf-FPG_IleRS PF06827.9 EPE32781.1 - 0.86 9.3 5.0 0.88 9.2 0.1 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS HMA PF00403.21 EPE32781.1 - 1.7 8.8 3.7 0.64 10.1 0.3 1.8 2 0 0 2 2 2 0 Heavy-metal-associated domain SSP160 PF06933.6 EPE32781.1 - 2.8 5.7 9.7 2.7 5.8 6.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sec3_C PF09763.4 EPE32781.1 - 4.5 5.2 5.8 5.2 5.0 4.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 Paramyxo_C PF01692.13 EPE32781.1 - 7.5 6.1 6.7 9.4 5.7 4.6 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c DUF566 PF04484.7 EPE32781.1 - 8.7 5.7 13.7 9.2 5.6 9.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) AAA_12 PF13087.1 EPE32782.1 - 1.4e-32 112.7 0.0 2.4e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPE32782.1 - 3.4e-25 88.9 0.0 4.1e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPE32782.1 - 5.5e-11 42.0 0.0 1.1e-09 37.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 EPE32782.1 - 6.6e-06 25.6 0.0 1.8e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EPE32782.1 - 2.6e-05 23.9 0.0 0.00034 20.2 0.0 2.6 3 0 0 3 3 3 1 Helicase AAA_30 PF13604.1 EPE32782.1 - 8.9e-05 22.1 0.0 0.00026 20.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE32782.1 - 0.00058 20.0 0.0 0.0024 18.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.1 EPE32782.1 - 0.0049 16.3 0.0 0.092 12.1 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EPE32782.1 - 0.01 15.3 0.0 3.2 7.1 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EPE32782.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EPE32782.1 - 0.015 14.2 0.0 0.27 10.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EPE32782.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.24 EPE32782.1 - 0.079 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE32782.1 - 0.17 12.7 0.3 0.72 10.6 0.1 2.1 2 1 0 2 2 1 0 AAA domain PhoH PF02562.11 EPE32782.1 - 0.22 10.7 0.0 0.53 9.4 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein TPR_12 PF13424.1 EPE32783.1 - 3.5e-16 58.8 0.0 1.1e-09 38.0 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPE32783.1 - 1.1e-12 47.3 0.0 0.013 15.4 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPE32783.1 - 2e-05 24.0 0.0 0.0026 17.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE32783.1 - 2.3e-05 24.6 0.1 0.015 15.8 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPE32783.1 - 4.8e-05 22.8 0.0 0.079 12.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPE32783.1 - 0.00012 21.6 0.0 0.0064 16.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPE32783.1 - 0.0015 18.8 0.0 0.0041 17.4 0.0 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPE32783.1 - 0.0032 17.0 0.0 0.18 11.4 0.0 2.3 2 1 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 EPE32783.1 - 0.0054 17.3 0.0 0.78 10.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPE32784.1 - 1.6e-20 72.8 1.5 8.3e-11 41.6 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPE32784.1 - 4.7e-15 54.9 1.4 0.0004 20.2 0.0 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPE32784.1 - 3.9e-12 44.9 0.5 2.4e-05 23.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPE32784.1 - 1.6e-11 43.2 3.5 0.00023 20.6 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPE32784.1 - 6e-11 41.3 1.7 0.002 17.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPE32784.1 - 1.2e-09 37.2 2.1 0.00091 18.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPE32784.1 - 7e-08 32.0 2.0 2.9e-06 26.8 0.2 2.7 2 1 0 2 2 2 1 TPR repeat TPR_6 PF13174.1 EPE32784.1 - 1.5e-07 31.4 0.4 0.24 11.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE32784.1 - 3.4e-06 27.5 1.2 0.00078 20.0 0.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPE32784.1 - 3.8e-06 27.0 0.0 0.51 11.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 EPE32784.1 - 5.5e-05 23.2 0.2 0.062 13.7 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPE32784.1 - 0.00027 21.2 0.8 0.019 15.2 0.2 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EPE32784.1 - 0.0012 18.9 0.2 4.1 7.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR PF01535.15 EPE32784.1 - 0.0069 16.2 0.4 2.1 8.5 0.0 2.7 3 0 0 3 3 3 1 PPR repeat Tcf25 PF04910.9 EPE32784.1 - 0.0083 15.1 0.0 0.013 14.4 0.0 1.4 1 1 0 1 1 1 1 Transcriptional repressor TCF25 MIT PF04212.13 EPE32784.1 - 0.065 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 EPE32784.1 - 0.073 12.5 0.1 0.18 11.2 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) APH PF01636.18 EPE32785.1 - 3e-09 36.9 0.0 1.3e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Metallophos PF00149.23 EPE32787.1 - 2.5e-09 36.8 0.1 4.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPE32787.1 - 1.4e-05 24.9 0.0 3e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPP_enzyme_N PF02776.13 EPE32788.1 - 5.5e-34 117.1 0.0 9.6e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPE32788.1 - 6.9e-18 64.7 0.0 2.7e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EPE32788.1 - 2.6e-14 53.0 0.0 4.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EPE32788.1 - 0.051 12.5 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase FAD_binding_2 PF00890.19 EPE32790.1 - 3.4e-30 105.2 0.1 2.5e-29 102.4 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE32790.1 - 2.3e-09 36.6 0.9 1.2e-08 34.2 0.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPE32790.1 - 4.9e-07 28.5 4.0 0.0023 16.4 0.1 2.9 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 EPE32790.1 - 9.4e-07 28.8 1.4 0.00033 20.6 0.7 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPE32790.1 - 2.5e-05 23.5 1.8 0.00032 19.9 1.3 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPE32790.1 - 0.00019 21.5 0.6 0.15 12.1 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE32790.1 - 0.0064 15.4 0.1 0.014 14.3 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPE32790.1 - 0.0096 15.9 0.4 0.031 14.2 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EPE32790.1 - 0.013 14.5 2.1 1.6 7.6 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EPE32790.1 - 0.045 12.6 0.1 0.045 12.6 0.1 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EPE32790.1 - 0.066 13.6 0.7 23 5.4 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 EPE32792.1 - 6e-16 58.0 3.3 1.1e-15 57.2 2.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE32792.1 - 1.1e-09 38.0 11.5 1.9e-09 37.3 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.23 EPE32793.1 - 3.2e-81 273.6 0.0 4.4e-81 273.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE32793.1 - 3e-06 26.9 0.0 5.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AA_permease PF00324.16 EPE32794.1 - 7.2e-121 403.8 44.2 8.1e-121 403.6 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE32794.1 - 6e-38 130.4 48.4 8e-38 130.0 33.5 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3754 PF12576.3 EPE32795.1 - 0.094 12.3 0.3 0.094 12.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Wzy_C PF04932.10 EPE32795.1 - 1.1 8.9 6.2 2.1 8.1 3.2 2.2 2 1 0 2 2 2 0 O-Antigen ligase Choline_transpo PF04515.7 EPE32795.1 - 3.2 6.3 8.6 2.4 6.8 2.6 2.1 2 0 0 2 2 2 0 Plasma-membrane choline transporter SUR7 PF06687.7 EPE32795.1 - 5.5 6.4 11.1 3 7.3 5.3 2.2 2 1 0 2 2 2 0 SUR7/PalI family Metallophos PF00149.23 EPE32796.1 - 2.8e-14 52.9 0.2 4.8e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPE32796.1 - 9.9e-05 22.2 0.1 0.00021 21.1 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HrpB7 PF09486.5 EPE32797.1 - 0.077 12.9 4.2 2.8 7.8 0.3 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Abhydrolase_6 PF12697.2 EPE32798.1 - 5.4e-21 75.5 0.4 6.9e-21 75.1 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE32798.1 - 1e-20 73.3 0.0 2.1e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EPE32798.1 - 7.6e-17 61.4 0.0 1.3e-16 60.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE32798.1 - 5.4e-06 26.1 0.1 0.00041 19.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EPE32798.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.15 EPE32798.1 - 0.0019 17.6 0.1 0.17 11.2 0.0 2.2 2 0 0 2 2 2 1 Putative esterase Lipase_3 PF01764.20 EPE32798.1 - 0.0055 16.3 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 EPE32798.1 - 0.0077 15.6 0.1 0.23 10.8 0.0 2.3 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF1749 PF08538.5 EPE32798.1 - 0.058 12.2 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) PGAP1 PF07819.8 EPE32798.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein CLP_protease PF00574.18 EPE32800.1 - 3.7e-75 251.5 0.0 4.4e-75 251.3 0.0 1.0 1 0 0 1 1 1 1 Clp protease DUF1180 PF06679.7 EPE32808.1 - 0.35 10.7 2.1 0.44 10.4 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glyco_hydro_43 PF04616.9 EPE32809.1 - 7.5e-53 179.4 3.0 9.1e-53 179.1 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 EPE32809.1 - 2.2e-37 127.9 2.1 4.6e-37 126.9 1.4 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 EPE32809.1 - 0.011 15.0 1.2 0.011 15.0 0.8 1.7 2 1 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain Fungal_trans_2 PF11951.3 EPE32810.1 - 2.9e-34 118.2 1.9 2.5e-32 111.9 1.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE32810.1 - 9.8e-10 38.1 5.0 1.9e-09 37.2 3.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.1 EPE32811.1 - 2.1e-21 76.8 0.0 2.8e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.14 EPE32812.1 - 3.1e-55 187.4 0.0 4e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE32812.1 - 2.8e-39 134.6 0.0 4.7e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPE32812.1 - 1.9e-06 27.0 0.2 0.023 13.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPE32812.1 - 1.3e-05 25.3 0.0 0.042 13.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE32812.1 - 6.2e-05 22.8 0.7 0.068 12.9 0.2 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 EPE32812.1 - 0.00011 21.2 0.4 0.052 12.4 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EPE32812.1 - 0.00013 21.8 0.2 0.02 14.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE32812.1 - 0.00041 19.3 0.3 0.019 13.9 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPE32812.1 - 0.00042 19.2 0.6 0.0088 14.9 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EPE32812.1 - 0.00043 20.2 0.3 0.001 19.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPE32812.1 - 0.0033 17.7 0.3 2 8.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EPE32812.1 - 0.013 14.1 0.5 0.028 13.0 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pribosyltran PF00156.22 EPE32812.1 - 0.019 14.7 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase domain HI0933_like PF03486.9 EPE32812.1 - 0.13 10.7 0.2 0.4 9.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein NmrA PF05368.8 EPE32813.1 - 4.5e-33 114.4 1.8 6.2e-33 113.9 1.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE32813.1 - 3.4e-07 30.4 0.6 7.5e-07 29.3 0.4 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE32813.1 - 3.2e-06 26.0 0.9 6.3e-06 25.0 0.4 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE32813.1 - 1.2e-05 24.9 0.1 4e-05 23.1 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EPE32813.1 - 0.00044 19.9 0.0 0.00093 18.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EPE32813.1 - 0.00051 19.1 0.3 0.00074 18.5 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EPE32813.1 - 0.0014 18.8 0.2 0.0052 17.0 0.1 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EPE32813.1 - 0.0037 16.2 0.5 0.0055 15.6 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.11 EPE32813.1 - 0.0049 17.4 0.4 0.012 16.1 0.3 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short PF00106.20 EPE32813.1 - 0.01 15.7 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.13 EPE32813.1 - 0.022 14.7 0.4 0.022 14.7 0.3 1.8 2 0 0 2 2 1 0 TrkA-N domain NAD_binding_4 PF07993.7 EPE32813.1 - 0.039 12.8 0.0 0.07 12.0 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein Chromate_transp PF02417.10 EPE32815.1 - 1.8e-54 183.8 36.7 9.3e-29 100.1 10.2 2.5 3 0 0 3 3 3 2 Chromate transporter NUDIX PF00293.23 EPE32816.1 - 2.5e-11 43.3 0.0 4.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain ZZ PF00569.12 EPE32816.1 - 0.00035 20.0 6.2 0.00059 19.3 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Tnp_zf-ribbon_2 PF13842.1 EPE32816.1 - 0.22 11.9 7.5 0.38 11.1 5.2 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Peptidase_M36 PF02128.10 EPE32817.1 - 3e-153 510.1 8.4 3.9e-153 509.7 5.8 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EPE32817.1 - 4.8e-12 45.1 2.1 4.2e-11 42.1 2.4 2.0 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EPE32817.1 - 0.022 14.4 0.0 0.055 13.1 0.0 1.7 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Sugar_tr PF00083.19 EPE32818.1 - 4.2e-85 286.0 26.1 5.5e-85 285.6 18.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE32818.1 - 1.2e-28 99.8 30.6 1.2e-28 99.8 21.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE32818.1 - 2e-05 23.0 5.7 2e-05 23.0 3.9 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.27 EPE32820.1 - 7.5e-78 253.8 21.3 2.3e-09 36.7 0.0 11.6 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 EPE32820.1 - 1.8e-46 157.2 0.7 2.8e-46 156.6 0.5 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EPE32820.1 - 1.4e-08 33.3 17.3 0.22 9.6 0.0 6.4 2 2 3 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPE32820.1 - 2.2e-06 26.6 13.9 0.089 11.5 0.0 5.5 4 2 1 5 5 5 3 Nup133 N terminal like NQRA PF05896.6 EPE32820.1 - 0.0099 15.0 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 2 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) SRP-alpha_N PF04086.8 EPE32820.1 - 0.012 14.9 2.5 0.021 14.2 1.7 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Utp12 PF04003.7 EPE32820.1 - 0.044 13.6 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family BBS2_Mid PF14783.1 EPE32820.1 - 0.089 12.5 0.0 12 5.6 0.0 4.2 6 0 0 6 6 6 0 Ciliary BBSome complex subunit 2, middle region MFS_1 PF07690.11 EPE32821.1 - 3.7e-35 121.2 29.6 3.7e-35 121.2 20.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 EPE32821.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) F-box PF00646.28 EPE32822.1 - 0.00036 20.1 0.0 0.00036 20.1 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EPE32822.1 - 0.0035 17.0 0.0 0.0086 15.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like Peptidase_M20 PF01546.23 EPE32823.1 - 6.2e-22 78.0 0.1 8.7e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPE32823.1 - 7.8e-15 54.6 0.2 2e-14 53.2 0.2 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3883 PF13020.1 EPE32824.1 - 5.8e-05 22.7 0.0 0.00019 21.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) HSP70 PF00012.15 EPE32825.1 - 8.5e-11 40.4 0.0 2.1e-09 35.8 0.0 2.4 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EPE32825.1 - 4.9e-07 28.6 0.1 0.0033 16.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EPE32825.1 - 0.017 14.7 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain APG6 PF04111.7 EPE32826.1 - 0.002 17.2 16.8 0.0037 16.3 11.7 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EPE32826.1 - 0.004 17.0 16.0 0.0082 16.0 11.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4337 PF14235.1 EPE32826.1 - 3.2 7.5 15.2 1.9 8.2 9.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) LCD1 PF09798.4 EPE32826.1 - 4.8 5.0 14.3 7 4.5 9.9 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein V_ATPase_I PF01496.14 EPE32826.1 - 6.3 4.5 8.1 8.7 4.0 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.11 EPE32826.1 - 6.5 5.2 5.8 6.8 5.1 2.8 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF3450 PF11932.3 EPE32826.1 - 9.9 5.3 19.7 1.6 7.9 9.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Ank_2 PF12796.2 EPE32827.1 - 5.3e-72 238.2 3.4 2.2e-14 53.5 0.0 6.9 3 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EPE32827.1 - 1.3e-56 185.7 8.7 1.1e-06 28.1 0.0 13.9 14 0 0 14 14 14 11 Ankyrin repeat Ank_3 PF13606.1 EPE32827.1 - 1.4e-43 142.5 4.5 4.5e-05 23.2 0.0 13.2 14 0 0 14 14 14 10 Ankyrin repeat Ank_4 PF13637.1 EPE32827.1 - 7.5e-43 144.1 1.0 3.7e-06 27.2 0.0 11.2 6 3 6 12 12 12 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE32827.1 - 9.9e-34 114.6 11.6 0.00041 20.5 0.0 12.3 6 3 7 13 13 13 9 Ankyrin repeats (many copies) Glyco_transf_22 PF03901.12 EPE32828.1 - 2e-74 251.0 18.8 2.4e-74 250.8 13.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.16 EPE32829.1 - 3.4e-109 364.7 0.0 4.2e-109 364.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EPE32829.1 - 1.1e-06 28.0 0.0 1.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EPE32829.1 - 0.0052 15.7 0.0 0.008 15.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DUF3543 PF12063.3 EPE32830.1 - 1.2e-85 286.5 0.0 2e-85 285.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EPE32830.1 - 1.1e-64 218.0 0.0 3.3e-64 216.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE32830.1 - 3.6e-43 147.5 0.0 7.9e-43 146.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EPE32830.1 - 0.012 14.4 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EPE32830.1 - 0.063 12.2 0.0 2.1 7.2 0.0 2.7 3 0 0 3 3 3 0 Kinase-like CMAS PF02353.15 EPE32831.1 - 1.5e-59 201.3 0.1 2.4e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase EF-hand_4 PF12763.2 EPE32831.1 - 6.9e-24 83.5 0.0 1.3e-12 47.4 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Methyltransf_23 PF13489.1 EPE32831.1 - 2.4e-12 46.8 0.0 5.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE32831.1 - 6.9e-08 32.8 0.0 1.8e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE32831.1 - 0.0016 18.7 0.0 0.0049 17.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain EF-hand_7 PF13499.1 EPE32831.1 - 0.0049 16.9 0.1 0.4 10.8 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair Methyltransf_12 PF08242.7 EPE32831.1 - 0.0066 16.8 0.0 0.028 14.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE32831.1 - 0.0073 16.8 1.2 0.053 14.1 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE32831.1 - 0.012 15.6 0.1 0.059 13.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EPE32831.1 - 0.025 14.1 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EPE32831.1 - 1.2 8.4 3.0 0.63 9.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Zn_clus PF00172.13 EPE32832.1 - 0.00058 19.7 6.1 0.0014 18.4 4.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RWP-RK PF02042.10 EPE32832.1 - 0.055 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RWP-RK domain CPT PF07931.7 EPE32839.1 - 0.075 12.6 0.7 4.8 6.7 0.1 3.1 2 2 2 4 4 4 0 Chloramphenicol phosphotransferase-like protein CENP-K PF11802.3 EPE32840.1 - 0.014 14.6 0.5 0.036 13.2 0.3 1.7 2 0 0 2 2 2 0 Centromere-associated protein K Baculo_PEP_C PF04513.7 EPE32840.1 - 0.018 14.8 1.3 0.052 13.3 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3958 PF13125.1 EPE32842.1 - 0.041 13.7 0.5 0.13 12.2 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) WD40 PF00400.27 EPE32848.1 - 1.1e-33 113.8 18.3 8.3e-08 31.8 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 EPE32848.1 - 4.2e-21 74.7 0.1 6.9e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ank_2 PF12796.2 EPE32851.1 - 2e-65 217.1 8.7 4.3e-13 49.4 2.2 7.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPE32851.1 - 1.2e-53 177.9 11.3 3.2e-09 36.7 0.0 10.4 5 2 6 11 11 11 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE32851.1 - 1.5e-46 155.9 15.9 5.4e-09 36.3 0.0 9.9 5 3 5 10 10 9 7 Ankyrin repeats (many copies) Ank PF00023.25 EPE32851.1 - 1.7e-46 153.7 7.9 4.5e-06 26.2 0.0 12.6 12 0 0 12 12 12 9 Ankyrin repeat Ank_3 PF13606.1 EPE32851.1 - 7.8e-35 115.4 5.9 0.0017 18.3 0.0 12.3 12 0 0 12 12 12 9 Ankyrin repeat HET PF06985.6 EPE32851.1 - 3.4e-21 75.8 4.9 5.1e-19 68.8 3.4 2.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 EPE32851.1 - 1.3e-06 28.1 0.0 4.2e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPE32851.1 - 5.4e-06 26.5 0.6 6.1e-05 23.0 0.0 3.0 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 EPE32851.1 - 4.2e-05 23.6 0.1 0.00018 21.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.17 EPE32851.1 - 0.00076 18.4 0.3 0.0014 17.5 0.2 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 EPE32851.1 - 0.011 15.8 0.1 0.14 12.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EPE32851.1 - 0.014 15.6 0.1 1.9 8.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 EPE32851.1 - 0.035 14.3 0.0 0.18 12.0 0.0 2.4 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE32851.1 - 0.057 14.2 0.0 0.55 11.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 EPE32852.1 - 9.4e-61 205.2 0.0 1.4e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE32852.1 - 2.2e-13 49.8 0.0 8.4e-13 48.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EPE32852.1 - 1.4e-06 27.8 13.0 1.4e-06 27.8 9.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE32852.1 - 4.3e-05 23.4 11.5 4.3e-05 23.4 7.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE32852.1 - 0.00014 21.5 11.8 0.00014 21.5 8.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-Nse PF11789.3 EPE32852.1 - 0.77 9.3 8.7 0.44 10.1 3.9 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit AT_hook PF02178.14 EPE32852.1 - 6.1 6.8 9.0 0.33 10.7 0.3 2.9 2 0 0 2 2 2 0 AT hook motif LRR_6 PF13516.1 EPE32853.1 - 9.9e-05 22.0 10.1 0.48 10.6 0.0 7.3 9 0 0 9 9 9 1 Leucine Rich repeat LRR_8 PF13855.1 EPE32853.1 - 0.00014 21.5 7.9 0.25 11.1 0.1 4.2 3 2 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EPE32853.1 - 0.00043 19.8 6.3 0.76 9.4 0.5 5.0 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) DUF4428 PF14471.1 EPE32853.1 - 0.0019 17.8 0.4 0.005 16.5 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) LRR_7 PF13504.1 EPE32853.1 - 0.014 15.4 3.9 32 5.3 0.0 5.9 6 1 1 7 7 7 0 Leucine rich repeat TAP42 PF04177.7 EPE32853.1 - 0.027 13.4 4.7 0.05 12.5 3.2 1.4 1 0 0 1 1 1 0 TAP42-like family FYVE PF01363.16 EPE32853.1 - 0.061 13.2 0.2 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 FYVE zinc finger Zw10 PF06248.8 EPE32854.1 - 7.4e-11 40.9 1.4 2.7e-08 32.4 0.7 2.5 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Peptidase_M16_C PF05193.16 EPE32855.1 - 3.4e-18 65.9 0.0 3.9e-13 49.4 0.0 2.8 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPE32855.1 - 7.5e-06 25.7 0.0 6.7e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Pro_isomerase PF00160.16 EPE32857.1 - 4.9e-45 153.5 1.0 6.6e-45 153.0 0.7 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.17 EPE32858.1 - 1.6e-07 31.7 0.2 3.6e-07 30.6 0.0 1.6 1 1 1 2 2 2 1 Ribosomal protein S13/S18 HET PF06985.6 EPE32859.1 - 2e-25 89.5 0.0 4.2e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF640 PF04852.7 EPE32859.1 - 0.1 12.7 0.7 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF640) CPDase PF07823.6 EPE32860.1 - 0.063 12.7 0.1 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Cu_bind_like PF02298.12 EPE32861.1 - 0.00016 21.3 0.1 0.00037 20.2 0.1 1.6 1 0 0 1 1 1 1 Plastocyanin-like domain E1-E2_ATPase PF00122.15 EPE32862.1 - 1.9e-45 154.7 7.2 3.8e-45 153.7 5.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EPE32862.1 - 7.5e-28 98.4 0.0 1.2e-27 97.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPE32862.1 - 3.2e-15 56.8 0.0 6.3e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EPE32862.1 - 9.5e-08 32.0 0.2 3.1e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain Bactofilin PF04519.8 EPE32863.1 - 1.2e-07 31.6 24.2 0.0086 16.0 5.3 4.4 1 1 4 5 5 5 5 Polymer-forming cytoskeletal DUF342 PF03961.8 EPE32863.1 - 0.001 17.6 33.5 0.057 11.8 1.3 4.2 1 1 2 4 4 4 4 Protein of unknown function (DUF342) DUF748 PF05359.6 EPE32863.1 - 0.0026 17.7 0.9 1.7 8.5 0.0 4.2 4 1 0 4 4 4 1 Domain of Unknown Function (DUF748) HET PF06985.6 EPE32864.1 - 2.8e-26 92.3 0.0 5.3e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.21 EPE32865.1 - 0.0044 17.2 7.6 0.016 15.5 2.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EPE32865.1 - 0.0066 16.6 0.2 7.5 7.0 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc-finger domain DUF1059 PF06348.6 EPE32865.1 - 0.047 13.5 0.2 5.6 6.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) zf-C2H2_4 PF13894.1 EPE32865.1 - 0.055 13.8 7.2 0.061 13.6 1.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE32865.1 - 0.2 11.9 0.2 0.2 11.9 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Peptidase_M35 PF02102.10 EPE32866.1 - 1.6e-25 89.5 21.8 3.5e-25 88.4 15.1 1.4 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EPE32866.1 - 3.8e-08 33.9 0.5 9.4e-08 32.6 0.4 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase GSIII_N PF12437.3 EPE32866.1 - 0.019 14.3 0.2 0.1 12.0 0.1 2.1 2 0 0 2 2 2 0 Glutamine synthetase type III N terminal ChitinaseA_N PF08329.5 EPE32866.1 - 0.068 12.9 1.2 0.83 9.4 0.0 2.4 2 0 0 2 2 2 0 Chitinase A, N-terminal domain Golgin_A5 PF09787.4 EPE32866.1 - 2.1 6.7 3.9 2.7 6.3 2.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 NAD_binding_10 PF13460.1 EPE32867.1 - 2.8e-07 30.7 0.1 1.2e-06 28.6 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE32867.1 - 1.4e-05 23.9 0.0 2.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EPE32867.1 - 2.8e-05 23.4 0.0 5.9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EPE32867.1 - 0.00011 21.7 0.1 0.00023 20.6 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPE32867.1 - 0.025 13.4 0.0 0.056 12.3 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Zn_clus PF00172.13 EPE32869.1 - 1.1e-07 31.6 14.9 3.3e-07 30.0 6.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EPE32870.1 - 7.8e-14 51.9 0.7 7.8e-14 51.9 0.5 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE32870.1 - 6.8e-08 32.3 0.9 1.7e-07 31.1 0.0 1.9 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EPE32870.1 - 9.6e-06 25.5 0.2 1.6e-05 24.7 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPE32870.1 - 0.0076 15.6 0.2 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EPE32870.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.14 EPE32870.1 - 0.04 12.6 0.1 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ank_2 PF12796.2 EPE32873.1 - 8.3e-63 208.7 8.8 5.3e-12 45.9 0.0 8.1 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EPE32873.1 - 1.9e-48 159.8 19.2 1.5e-05 24.5 0.0 13.7 12 3 1 13 13 13 10 Ankyrin repeat Ank_4 PF13637.1 EPE32873.1 - 2.9e-40 135.9 10.6 3.1e-09 37.1 0.0 10.2 7 2 3 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE32873.1 - 6.1e-37 121.9 13.3 0.00018 21.4 0.0 13.8 15 1 0 15 15 15 9 Ankyrin repeat Ank_5 PF13857.1 EPE32873.1 - 1.7e-34 117.0 15.7 6.8e-09 35.6 0.0 11.2 8 4 4 12 12 12 7 Ankyrin repeats (many copies) adh_short PF00106.20 EPE32874.1 - 4e-17 62.6 0.1 5.7e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE32874.1 - 4.5e-07 29.7 0.1 6.7e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EPE32874.1 - 0.095 12.8 0.3 0.24 11.4 0.2 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CRCB PF02537.10 EPE32874.1 - 0.096 12.5 0.2 0.32 10.8 0.1 1.9 2 0 0 2 2 2 0 CrcB-like protein Fungal_trans PF04082.13 EPE32875.1 - 2.9e-15 55.8 0.1 4.5e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EPE32876.1 - 4.2e-82 276.1 18.6 4.9e-82 275.9 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE32876.1 - 5.7e-13 48.3 23.9 5.7e-13 48.3 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE32876.1 - 0.00087 17.7 2.1 0.00087 17.7 1.4 3.7 2 2 2 4 4 4 3 MFS/sugar transport protein DUF605 PF04652.11 EPE32877.1 - 1.5 8.1 21.4 2.1 7.6 14.8 1.1 1 0 0 1 1 1 0 Vta1 like Peptidase_M36 PF02128.10 EPE32881.1 - 1.7e-148 494.4 4.9 2.2e-148 494.1 3.4 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EPE32881.1 - 6.2e-12 44.7 1.2 1.5e-11 43.5 0.8 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EPE32881.1 - 0.014 15.1 0.0 0.059 13.1 0.0 2.1 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Trypan_PARP PF05887.6 EPE32881.1 - 0.14 12.0 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HET PF06985.6 EPE32882.1 - 1e-19 71.0 0.6 1.2e-16 61.0 0.2 2.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EPE32883.1 - 7.8e-23 81.1 0.0 1.6e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Securin PF04856.8 EPE32884.1 - 0.0039 16.9 4.4 0.0053 16.4 1.2 2.6 1 1 0 2 2 2 1 Securin sister-chromatid separation inhibitor Tropomyosin_1 PF12718.2 EPE32885.1 - 1.2e-19 70.5 22.7 1.4e-19 70.3 15.7 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EPE32885.1 - 0.00011 21.3 22.7 0.00017 20.7 15.7 1.3 1 1 0 1 1 1 1 Tropomyosin GAS PF13851.1 EPE32885.1 - 0.00031 19.9 15.0 0.00031 19.9 10.4 2.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 EPE32885.1 - 0.00055 19.6 21.9 0.0011 18.7 1.0 3.6 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 EPE32885.1 - 0.0017 18.3 9.9 0.029 14.3 1.9 2.8 2 0 0 2 2 2 1 bZIP transcription factor PspA_IM30 PF04012.7 EPE32885.1 - 0.0021 17.4 16.6 0.058 12.7 3.5 2.2 1 1 1 2 2 2 2 PspA/IM30 family CENP-Q PF13094.1 EPE32885.1 - 0.0029 17.6 21.0 0.12 12.3 7.0 2.1 1 1 1 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 EPE32885.1 - 0.0037 17.1 14.9 0.029 14.2 2.3 2.2 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.15 EPE32885.1 - 0.0061 16.3 19.3 0.0091 15.7 1.8 2.7 1 1 1 2 2 2 1 Prefoldin subunit Phage_GP20 PF06810.6 EPE32885.1 - 0.0071 15.8 18.8 0.19 11.1 5.7 2.6 1 1 1 2 2 2 1 Phage minor structural protein GP20 CENP-K PF11802.3 EPE32885.1 - 0.013 14.7 1.9 0.013 14.7 1.3 1.9 1 1 1 2 2 2 0 Centromere-associated protein K IncA PF04156.9 EPE32885.1 - 0.017 14.7 19.8 0.061 12.9 5.9 2.1 1 1 1 2 2 2 0 IncA protein DUF972 PF06156.8 EPE32885.1 - 0.019 15.2 11.1 0.42 10.9 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) BicD PF09730.4 EPE32885.1 - 0.042 12.2 18.4 0.037 12.3 4.1 2.0 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D ATG16 PF08614.6 EPE32885.1 - 0.069 12.9 16.1 1 9.1 2.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_CLD_2 PF14197.1 EPE32885.1 - 0.071 13.0 7.4 1.5 8.8 0.2 3.0 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Syntaxin-6_N PF09177.6 EPE32885.1 - 0.1 13.0 12.9 0.43 11.0 1.9 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Pox_A_type_inc PF04508.7 EPE32885.1 - 0.11 12.3 0.3 0.11 12.3 0.2 3.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat PilJ PF13675.1 EPE32885.1 - 0.13 12.5 5.5 1.1 9.5 0.4 2.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term CENP-F_leu_zip PF10473.4 EPE32885.1 - 0.18 11.6 19.7 0.032 14.0 3.6 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.11 EPE32885.1 - 0.19 11.8 22.8 0.14 12.2 6.3 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Fib_alpha PF08702.5 EPE32885.1 - 0.2 11.8 10.8 1.3 9.0 0.3 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 EPE32885.1 - 0.21 9.4 10.6 0.28 8.9 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_27 PF13514.1 EPE32885.1 - 0.24 9.0 21.3 0.12 10.0 5.5 2.0 1 1 1 2 2 2 0 AAA domain Striatin PF08232.7 EPE32885.1 - 0.25 11.6 14.6 0.79 10.0 1.1 2.3 1 1 1 2 2 2 0 Striatin family FH2 PF02181.18 EPE32885.1 - 0.3 9.9 10.7 0.13 11.0 1.5 2.0 1 1 0 2 2 2 0 Formin Homology 2 Domain Filament PF00038.16 EPE32885.1 - 0.31 10.4 18.5 0.17 11.3 1.5 2.1 1 1 0 2 2 2 0 Intermediate filament protein BLOC1_2 PF10046.4 EPE32885.1 - 0.35 11.0 14.4 0.16 12.1 1.0 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.8 EPE32885.1 - 0.39 10.0 6.8 0.63 9.3 0.5 2.2 1 1 1 2 2 2 0 fzo-like conserved region Fmp27_WPPW PF10359.4 EPE32885.1 - 0.54 8.6 14.9 1.6 7.0 3.0 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.17 EPE32885.1 - 0.56 10.2 18.3 0.21 11.6 2.1 2.8 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Transposase_22 PF02994.9 EPE32885.1 - 0.59 8.5 14.6 0.053 12.0 3.4 2.0 1 1 1 2 2 2 0 L1 transposable element Spectrin PF00435.16 EPE32885.1 - 0.64 10.3 18.2 2.8 8.2 4.0 2.7 1 1 1 2 2 2 0 Spectrin repeat T2SM PF04612.7 EPE32885.1 - 0.64 9.7 7.3 2.1 8.1 0.2 2.5 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein M DUF4140 PF13600.1 EPE32885.1 - 0.73 10.3 14.4 2.1 8.8 1.3 2.7 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Uds1 PF15456.1 EPE32885.1 - 0.89 9.5 11.0 4 7.4 7.1 2.3 1 1 0 1 1 1 0 Up-regulated During Septation Ax_dynein_light PF10211.4 EPE32885.1 - 0.9 9.3 19.5 1.6 8.5 2.6 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain DUF904 PF06005.7 EPE32885.1 - 1 9.7 21.0 0.72 10.1 3.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF904) AAA_13 PF13166.1 EPE32885.1 - 1.1 7.6 20.5 2.7 6.3 14.2 1.6 1 1 0 1 1 1 0 AAA domain DUF3818 PF12825.2 EPE32885.1 - 1.1 7.8 8.8 1.4 7.5 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) HSP70 PF00012.15 EPE32885.1 - 1.4 6.7 14.8 1.8 6.4 10.3 1.2 1 0 0 1 1 1 0 Hsp70 protein SlyX PF04102.7 EPE32885.1 - 1.6 9.1 12.5 0.64 10.4 1.2 3.5 1 1 2 3 3 3 0 SlyX DUF812 PF05667.6 EPE32885.1 - 1.7 7.0 18.4 5 5.5 12.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) HCMV_UL139 PF12507.3 EPE32885.1 - 1.7 8.8 10.0 30 4.7 3.3 3.0 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein ERM PF00769.14 EPE32885.1 - 2 7.8 22.5 0.14 11.6 4.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3552 PF12072.3 EPE32885.1 - 2.2 7.4 21.8 4.7 6.3 6.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DivIC PF04977.10 EPE32885.1 - 2.8 7.4 23.2 0.65 9.5 3.0 3.5 1 1 1 3 3 3 0 Septum formation initiator Cluap1 PF10234.4 EPE32885.1 - 3 6.9 16.8 2.1 7.5 6.0 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 APG6 PF04111.7 EPE32885.1 - 3.5 6.5 23.8 0.4 9.6 5.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 bZIP_Maf PF03131.12 EPE32885.1 - 3.5 7.9 9.8 1.1 9.6 1.1 2.5 1 1 2 3 3 3 0 bZIP Maf transcription factor Prefoldin PF02996.12 EPE32885.1 - 3.6 7.2 16.6 4.1e+02 0.6 9.6 3.2 1 1 1 2 2 2 0 Prefoldin subunit DUF4407 PF14362.1 EPE32885.1 - 3.6 6.4 16.8 25 3.7 11.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Spc34 PF08657.5 EPE32885.1 - 3.6 7.1 13.7 0.19 11.3 3.6 2.3 1 1 1 2 2 2 0 DASH complex subunit Spc34 DUF3287 PF11690.3 EPE32885.1 - 3.8 7.6 6.5 7.5 6.6 0.1 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF3287) DUF2937 PF11157.3 EPE32885.1 - 3.8 6.8 8.3 4.8 6.4 1.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) EHN PF06441.7 EPE32885.1 - 4.2 7.3 7.4 1.5 8.8 1.1 2.3 1 1 1 2 2 2 0 Epoxide hydrolase N terminus FlaC_arch PF05377.6 EPE32885.1 - 4.3 7.3 8.8 8.1 6.4 0.7 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 EPE32885.1 - 4.4 5.8 18.0 5.1 5.6 1.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein MIS13 PF08202.6 EPE32885.1 - 4.7 6.1 14.7 33 3.4 10.2 2.0 1 1 0 1 1 1 0 Mis12-Mtw1 protein family DUF1192 PF06698.6 EPE32885.1 - 5.3 6.9 11.6 0.11 12.2 1.3 2.9 2 2 0 3 3 3 0 Protein of unknown function (DUF1192) Mnd1 PF03962.10 EPE32885.1 - 5.3 6.6 20.6 1.2 8.7 8.0 2.6 1 1 2 3 3 3 0 Mnd1 family DUF16 PF01519.11 EPE32885.1 - 5.6 7.2 13.1 3.3e+02 1.5 9.1 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 LTXXQ PF07813.7 EPE32885.1 - 5.7 7.4 11.1 74 3.8 7.7 2.2 1 1 0 1 1 1 0 LTXXQ motif family protein DivIVA PF05103.8 EPE32885.1 - 5.9 6.9 20.1 47 4.0 12.8 2.6 1 1 0 1 1 1 0 DivIVA protein Med9 PF07544.8 EPE32885.1 - 6.1 6.6 11.5 0.36 10.5 0.8 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Viral_P18 PF04521.8 EPE32885.1 - 6.2 6.2 8.3 5 6.6 0.7 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF1003 PF06210.6 EPE32885.1 - 7.9 6.4 6.8 23 4.9 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Rootletin PF15035.1 EPE32885.1 - 8.6 6.2 16.4 39 4.1 11.3 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TSC22 PF01166.13 EPE32885.1 - 8.8 6.3 9.4 0.69 9.9 1.3 2.9 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF4200 PF13863.1 EPE32885.1 - 9 6.2 24.4 21 5.1 11.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Nop25 PF09805.4 EPE32886.1 - 4.9e-31 107.6 12.1 4.9e-31 107.6 8.4 2.2 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) FlaG PF03646.10 EPE32886.1 - 0.42 10.7 9.4 0.045 13.8 2.1 2.2 2 0 0 2 2 2 0 FlaG protein Telomere_Sde2 PF13019.1 EPE32886.1 - 2.9 7.5 7.9 5.5 6.6 5.5 1.4 1 0 0 1 1 1 0 Telomere stability and silencing DUF4661 PF15576.1 EPE32886.1 - 3.7 7.1 5.4 5.4 6.5 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) ATP-synt_S1 PF05827.7 EPE32887.1 - 1.5e-33 116.3 0.0 1.7e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Fcf1 PF04900.7 EPE32888.1 - 9.8e-38 128.3 0.8 2.1e-37 127.2 0.1 1.7 2 0 0 2 2 2 1 Fcf1 DUF4200 PF13863.1 EPE32888.1 - 0.78 9.7 8.2 0.26 11.2 3.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Plasmodium_Vir PF05795.6 EPE32890.1 - 0.0015 17.8 1.0 0.0019 17.4 0.7 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Rifin_STEVOR PF02009.11 EPE32890.1 - 0.0042 16.7 0.5 0.0067 16.1 0.3 1.2 1 0 0 1 1 1 1 Rifin/stevor family FixQ PF05545.6 EPE32890.1 - 0.04 13.5 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Podoplanin PF05808.6 EPE32890.1 - 0.044 13.3 9.2 0.084 12.4 6.4 1.4 1 0 0 1 1 1 0 Podoplanin MIP-T3 PF10243.4 EPE32890.1 - 0.11 11.0 5.9 0.14 10.5 4.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TMEM154 PF15102.1 EPE32890.1 - 0.24 11.0 8.9 1.9 8.1 6.2 2.1 1 1 0 1 1 1 0 TMEM154 protein family Macoilin PF09726.4 EPE32890.1 - 0.9 7.7 10.7 1.2 7.3 7.4 1.1 1 0 0 1 1 1 0 Transmembrane protein SSP160 PF06933.6 EPE32890.1 - 2.1 6.2 25.3 4.2 5.2 17.5 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dynamin_M PF01031.15 EPE32891.1 - 1.4e-18 66.6 0.0 1.2e-13 50.5 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EPE32891.1 - 0.0077 16.1 0.0 0.03 14.2 0.0 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_N PF00350.18 EPE32892.1 - 2.4e-23 82.7 0.0 5.6e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EPE32892.1 - 4e-06 26.7 0.1 3.2e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EPE32892.1 - 0.00043 19.8 0.0 0.72 9.2 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Miro PF08477.8 EPE32892.1 - 0.0029 18.0 0.0 0.0099 16.3 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 EPE32892.1 - 0.02 15.2 0.3 0.14 12.4 0.0 2.0 1 1 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EPE32892.1 - 0.024 13.9 0.1 4.3 6.5 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.22 EPE32892.1 - 0.034 14.4 0.1 0.097 12.9 0.0 1.9 1 1 1 2 2 2 0 ABC transporter AAA_21 PF13304.1 EPE32892.1 - 0.035 14.0 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPE32892.1 - 0.041 13.4 0.0 0.098 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 EPE32892.1 - 0.1 11.2 0.1 0.18 10.4 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Endothelin PF00322.12 EPE32893.1 - 0.0083 15.3 0.7 0.29 10.4 0.1 2.8 2 0 0 2 2 2 2 Endothelin family Peptidase_M19 PF01244.16 EPE32894.1 - 2.9e-84 282.7 0.0 3.5e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.9 EPE32894.1 - 0.04 13.4 0.0 0.057 12.9 0.0 1.5 1 1 0 1 1 1 0 Amidohydrolase DUF2938 PF11158.3 EPE32895.1 - 0.055 12.8 0.2 0.055 12.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) PqiA PF04403.8 EPE32895.1 - 0.056 13.0 1.8 0.06 12.9 1.2 1.0 1 0 0 1 1 1 0 Paraquat-inducible protein A RhoGAP PF00620.22 EPE32896.1 - 4.2e-17 62.1 0.6 8.6e-17 61.1 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EPE32896.1 - 1.2e-13 51.0 0.0 4.8e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EPE32896.1 - 9e-12 44.5 0.0 2.2e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) N-SET PF11764.3 EPE32897.1 - 7.9e-41 139.7 0.3 7.9e-41 139.7 0.2 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 EPE32897.1 - 1.5e-23 83.8 0.3 1.5e-23 83.8 0.2 3.1 3 1 0 3 3 3 1 SET domain SET_assoc PF11767.3 EPE32897.1 - 3.8e-17 61.3 0.1 1e-16 59.9 0.1 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_5 PF13893.1 EPE32897.1 - 0.031 14.1 0.2 1.6 8.6 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPE32897.1 - 0.17 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AAA PF00004.24 EPE32899.1 - 1.1e-37 129.1 0.0 3e-14 53.3 0.0 3.8 3 1 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE32899.1 - 7.8e-15 55.1 1.3 0.006 16.7 0.0 6.3 4 2 1 5 5 4 3 AAA domain AAA_17 PF13207.1 EPE32899.1 - 1.6e-09 38.6 1.0 0.0049 17.6 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EPE32899.1 - 3.6e-08 33.2 0.2 0.33 10.5 0.1 4.6 3 1 0 3 3 3 3 AAA domain AAA_19 PF13245.1 EPE32899.1 - 2.1e-07 30.5 2.0 0.018 14.7 0.0 3.2 3 0 0 3 3 2 2 Part of AAA domain AAA_5 PF07728.9 EPE32899.1 - 3.2e-07 30.1 0.0 0.0037 16.9 0.0 3.6 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EPE32899.1 - 7.5e-07 28.4 0.0 0.035 13.1 0.0 3.4 2 2 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EPE32899.1 - 8.6e-07 29.3 5.1 0.062 13.5 0.0 4.6 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.17 EPE32899.1 - 9.5e-07 28.9 0.2 0.56 10.3 0.0 4.6 5 0 0 5 5 5 2 RNA helicase AAA_33 PF13671.1 EPE32899.1 - 7.9e-06 25.8 0.1 0.22 11.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 EPE32899.1 - 2.7e-05 23.4 0.0 0.29 10.2 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EPE32899.1 - 5.6e-05 23.1 0.0 1.2 9.0 0.0 4.2 3 1 1 4 4 4 2 AAA ATPase domain AAA_24 PF13479.1 EPE32899.1 - 6.7e-05 22.5 0.3 1.1 8.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 EPE32899.1 - 8.5e-05 22.5 0.0 0.16 11.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 EPE32899.1 - 0.00016 21.7 0.0 2.2 8.3 0.0 3.9 3 1 0 3 3 3 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EPE32899.1 - 0.0011 18.5 0.4 1.2 8.5 0.0 2.9 3 0 0 3 3 2 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 EPE32899.1 - 0.0012 18.3 0.5 7.7 5.9 0.1 3.8 3 1 0 3 3 3 0 IstB-like ATP binding protein Torsin PF06309.6 EPE32899.1 - 0.0022 17.8 0.0 0.35 10.7 0.0 3.0 3 0 0 3 3 3 1 Torsin AAA_29 PF13555.1 EPE32899.1 - 0.0053 16.2 0.0 25 4.4 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain SRP54 PF00448.17 EPE32899.1 - 0.014 14.8 0.5 0.81 9.0 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EPE32899.1 - 0.019 14.4 0.1 13 5.1 0.0 3.7 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EPE32899.1 - 0.026 14.2 0.2 4.9 6.8 0.0 2.8 2 0 0 2 2 2 0 NTPase Zot PF05707.7 EPE32899.1 - 0.071 12.5 1.9 1.6 8.1 0.0 3.4 4 0 0 4 4 4 0 Zonular occludens toxin (Zot) Asp PF00026.18 EPE32901.1 - 1.8e-07 30.7 0.1 2.7e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF3609 PF12259.3 EPE32901.1 - 0.23 10.0 0.0 0.38 9.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) YcfA PF07927.7 EPE32902.1 - 0.14 12.0 0.2 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 YcfA-like protein DUF4188 PF13826.1 EPE32903.1 - 8e-25 87.1 0.1 1.1e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EPE32903.1 - 0.0074 15.3 0.5 1.6 7.7 0.0 2.0 1 1 1 2 2 2 2 Haem-containing dehydratase Adenylsucc_synt PF00709.16 EPE32904.1 - 1.5e-156 521.3 0.0 1.7e-156 521.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Fungal_trans PF04082.13 EPE32905.1 - 5.4e-11 41.8 0.6 1.8e-10 40.1 0.0 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE32905.1 - 0.037 13.9 4.3 0.077 12.9 3.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.2 EPE32906.1 - 1.9e-05 24.6 1.9 0.21 11.8 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPE32906.1 - 0.00023 21.2 1.7 0.04 14.0 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 EPE32906.1 - 0.00089 19.0 0.1 0.57 9.9 0.0 2.3 2 0 0 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 EPE32906.1 - 0.003 17.7 9.0 0.074 13.4 0.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EPE32906.1 - 0.0064 16.5 1.0 0.56 10.3 0.2 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF3505 PF12013.3 EPE32906.1 - 0.019 15.2 0.8 0.045 14.0 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 EPE32906.1 - 0.13 12.5 3.7 4.4 7.7 0.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EPE32906.1 - 0.29 11.5 4.3 5.8 7.4 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.24 EPE32907.1 - 9.9e-46 155.3 0.0 7.4e-45 152.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE32907.1 - 4.7e-09 35.9 0.0 1.2e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE32907.1 - 0.009 15.8 0.0 0.021 14.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EPE32907.1 - 0.027 13.5 0.1 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Proteasome PF00227.21 EPE32908.1 - 8.4e-36 123.0 0.0 9.7e-36 122.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 EPE32909.1 - 9.2e-25 85.5 5.6 8e-08 31.8 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EPE32909.1 - 0.026 12.6 0.1 9.2 4.2 0.0 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Histone_HNS PF00816.16 EPE32909.1 - 0.14 12.6 5.3 0.09 13.2 1.0 2.4 2 0 0 2 2 2 0 H-NS histone family UCH PF00443.24 EPE32910.1 - 9.1e-28 97.1 0.0 1.3e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPE32910.1 - 3e-11 43.2 0.3 5.9e-11 42.3 0.2 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUF3902 PF13042.1 EPE32911.1 - 0.0015 17.8 6.0 0.0034 16.6 4.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3902) AA_permease_2 PF13520.1 EPE32912.1 - 7.1e-54 182.9 57.3 9.5e-54 182.5 39.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE32912.1 - 1.3e-17 63.3 50.4 1.8e-17 62.8 35.0 1.1 1 0 0 1 1 1 1 Amino acid permease OAD_gamma PF04277.8 EPE32912.1 - 1.6 9.1 7.5 1.5 9.2 0.8 3.4 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF3377 PF11857.3 EPE32912.1 - 8.8 6.0 7.2 0.58 9.8 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) adh_short PF00106.20 EPE32913.1 - 9.4e-23 80.9 0.2 1.3e-22 80.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE32913.1 - 1e-14 54.9 0.0 1.3e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE32913.1 - 7.8e-10 38.7 0.1 1.8e-09 37.4 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE32913.1 - 0.00014 21.4 0.0 0.015 14.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPE32913.1 - 0.035 12.9 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Oxidored_FMN PF00724.15 EPE32914.1 - 1.9e-88 296.7 0.0 2.2e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NAD_binding_10 PF13460.1 EPE32915.1 - 8.2e-15 55.2 0.0 1.7e-14 54.2 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE32915.1 - 9.2e-06 25.0 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Methyltransf_33 PF10017.4 EPE32916.1 - 5e-27 94.2 0.0 9.2e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 EPE32916.1 - 0.00034 20.9 0.0 0.0014 18.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain FAD_binding_4 PF01565.18 EPE32917.1 - 1.9e-15 56.5 0.5 3.6e-15 55.6 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE32917.1 - 1.5e-10 40.8 0.2 3.5e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Trp_DMAT PF11991.3 EPE32918.1 - 1e-125 419.7 0.0 1.2e-125 419.4 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Catalase PF00199.14 EPE32919.1 - 5.3e-118 394.0 0.0 7e-118 393.6 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EPE32919.1 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive HAD PF12710.2 EPE32920.1 - 1.5e-15 57.8 0.0 2e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPE32920.1 - 0.00025 21.3 0.0 0.00072 19.8 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPE32920.1 - 0.0022 17.2 0.0 0.29 10.2 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase UMPH-1 PF05822.7 EPE32920.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) HET PF06985.6 EPE32921.1 - 1.1e-35 122.8 0.5 1.9e-35 122.0 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CDP-OH_P_transf PF01066.16 EPE32922.1 - 5e-17 62.0 8.8 9.3e-17 61.1 5.8 1.7 1 1 1 2 2 2 1 CDP-alcohol phosphatidyltransferase FAM47 PF14642.1 EPE32924.1 - 0.21 10.8 2.8 0.28 10.4 1.9 1.1 1 0 0 1 1 1 0 FAM47 family HSP70 PF00012.15 EPE32926.1 - 1.1e-170 568.5 8.0 1.1e-170 568.5 5.6 2.2 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EPE32926.1 - 1.8e-13 49.7 0.1 4.8e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EPE32926.1 - 0.00067 19.4 2.9 0.2 11.5 0.2 3.7 2 2 0 2 2 2 2 Cell division protein FtsA DUF3665 PF12427.3 EPE32926.1 - 0.29 10.5 1.4 4.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase HSP70 PF00012.15 EPE32927.1 - 2.9e-268 890.7 6.4 3.3e-268 890.5 4.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPE32927.1 - 9.6e-18 63.8 0.1 2.7e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EPE32927.1 - 0.0027 17.3 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EPE32927.1 - 0.008 15.3 0.0 0.036 13.1 0.0 2.1 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 EPE32927.1 - 0.038 13.8 3.5 1.4 8.7 0.2 3.2 2 2 0 2 2 2 0 Cell division protein FtsA StbA PF06406.6 EPE32927.1 - 0.049 12.5 0.0 0.089 11.7 0.0 1.4 1 0 0 1 1 1 0 StbA protein OMPdecase PF00215.19 EPE32928.1 - 3.6e-89 298.0 0.0 4.3e-89 297.7 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Sod_Cu PF00080.15 EPE32928.1 - 0.042 13.9 0.1 2.6 8.1 0.0 3.2 3 1 1 4 4 4 0 Copper/zinc superoxide dismutase (SODC) Spt20 PF12090.3 EPE32930.1 - 1.2e-42 145.3 0.0 1.2e-42 145.3 0.0 4.7 3 2 0 3 3 3 1 Spt20 family Remorin_C PF03763.8 EPE32930.1 - 0.45 10.0 37.3 0.38 10.2 13.0 3.9 3 0 0 3 3 3 0 Remorin, C-terminal region DUF3128 PF11326.3 EPE32931.1 - 4.3e-27 94.0 1.3 7.4e-27 93.3 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Pox_A_type_inc PF04508.7 EPE32931.1 - 0.093 12.5 2.1 0.28 11.0 1.4 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat RNA12 PF10443.4 EPE32932.1 - 2.3e-169 563.4 0.1 2.9e-169 563.1 0.1 1.1 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EPE32932.1 - 4.3e-05 23.3 0.1 0.00019 21.2 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 EPE32932.1 - 0.0064 16.1 0.0 0.043 13.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 EPE32932.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) FBPase PF00316.15 EPE32933.1 - 2.2e-117 391.5 0.0 2.8e-109 364.8 0.0 2.0 2 0 0 2 2 2 2 Fructose-1-6-bisphosphatase CwfJ_C_1 PF04677.10 EPE32934.1 - 7.1e-32 109.6 0.0 1.2e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EPE32934.1 - 5.8e-25 87.6 0.1 5.8e-25 87.6 0.1 2.3 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 ATP_bind_1 PF03029.12 EPE32935.1 - 4.9e-76 255.3 0.0 6.7e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EPE32935.1 - 3.8e-05 23.2 0.0 0.005 16.2 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EPE32935.1 - 8.5e-05 21.4 0.0 0.022 13.5 0.0 2.3 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EPE32935.1 - 0.0006 20.2 0.0 0.5 10.8 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EPE32935.1 - 0.00064 19.8 0.0 0.0028 17.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EPE32935.1 - 0.00082 18.8 0.4 0.0012 18.3 0.3 1.6 1 1 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 EPE32935.1 - 0.0012 18.8 0.0 0.0037 17.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PRK PF00485.13 EPE32935.1 - 0.0017 17.9 0.1 0.042 13.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EPE32935.1 - 0.0019 18.0 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPE32935.1 - 0.0025 16.9 0.0 0.0058 15.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EPE32935.1 - 0.0034 17.0 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EPE32935.1 - 0.0036 18.1 0.0 0.028 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPE32935.1 - 0.0048 16.9 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.13 EPE32935.1 - 0.0048 16.1 0.1 0.097 11.9 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B SRP54 PF00448.17 EPE32935.1 - 0.0054 16.2 0.0 0.03 13.7 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EPE32935.1 - 0.0064 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EPE32935.1 - 0.0066 15.3 0.6 0.018 13.9 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain MobB PF03205.9 EPE32935.1 - 0.0084 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 EPE32935.1 - 0.0095 15.1 0.0 1.1 8.4 0.0 2.9 3 0 0 3 3 3 1 ADP-ribosylation factor family G-alpha PF00503.15 EPE32935.1 - 0.012 14.3 0.2 0.69 8.5 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit cobW PF02492.14 EPE32935.1 - 0.016 14.6 0.0 0.64 9.4 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 EPE32935.1 - 0.024 13.6 0.0 0.085 11.8 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain PduV-EutP PF10662.4 EPE32935.1 - 0.064 12.7 0.1 0.72 9.3 0.0 2.6 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Adeno_IVa2 PF02456.10 EPE32935.1 - 0.11 11.1 0.1 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein 6PF2K PF01591.13 EPE32935.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase A_deaminase PF00962.17 EPE32936.1 - 3.1e-72 243.3 0.0 3.5e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase HET PF06985.6 EPE32937.1 - 3.4e-38 130.9 2.0 5.7e-38 130.2 1.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SBP_bac_3 PF00497.15 EPE32937.1 - 0.1 11.8 0.0 0.51 9.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Fungal_trans PF04082.13 EPE32938.1 - 1.4e-29 102.8 0.2 2.2e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE32938.1 - 0.00024 20.9 13.9 0.00024 20.9 9.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 EPE32939.1 - 4.8e-13 49.5 0.0 6.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE32939.1 - 1.2e-09 37.9 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPE32939.1 - 3.8e-05 23.0 0.1 5.5e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EPE32939.1 - 6.3e-05 22.0 0.1 8e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 EPE32939.1 - 0.00093 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.19 EPE32939.1 - 0.0049 17.1 0.1 0.0071 16.6 0.1 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PCP PF02429.10 EPE32939.1 - 0.0068 16.5 0.1 0.01 15.9 0.1 1.2 1 0 0 1 1 1 1 Peridinin-chlorophyll A binding protein OCD_Mu_crystall PF02423.10 EPE32940.1 - 1.9e-10 40.0 3.8 3.4e-05 22.7 0.0 3.0 3 1 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family DUF936 PF06075.7 EPE32940.1 - 0.1 11.5 10.7 0.14 11.0 7.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Macoilin PF09726.4 EPE32940.1 - 5 5.2 8.8 6.5 4.8 6.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Aldo_ket_red PF00248.16 EPE32941.1 - 7.9e-62 208.6 0.0 9.6e-62 208.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pro_CA PF00484.14 EPE32942.1 - 2.7e-44 150.8 0.0 3.4e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_L7Ae PF01248.21 EPE32943.1 - 7.2e-21 73.5 0.9 1.2e-20 72.7 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATP_bind_3 PF01171.15 EPE32944.1 - 1.3e-18 67.0 0.0 2.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 EPE32944.1 - 0.0017 17.7 1.0 0.0017 17.7 0.7 3.0 4 0 0 4 4 4 1 RecR protein DUF2392 PF10288.4 EPE32944.1 - 0.0034 17.6 0.0 0.0087 16.3 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EPE32944.1 - 0.023 13.2 0.0 0.042 12.4 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.15 EPE32944.1 - 0.15 11.7 8.2 0.34 10.6 0.7 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) RNHCP PF12647.2 EPE32944.1 - 5.7 6.8 7.1 1.9 8.3 0.1 2.8 3 0 0 3 3 3 0 RNHCP domain DZR PF12773.2 EPE32944.1 - 9.1 6.1 11.2 12 5.8 0.4 3.3 3 0 0 3 3 3 0 Double zinc ribbon GATase PF00117.23 EPE32947.1 - 3.6e-06 26.5 0.0 5.7e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Lipoprotein_1 PF00820.14 EPE32947.1 - 0.13 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein Cu_amine_oxid PF01179.15 EPE32948.1 - 2.9e-157 523.6 0.1 3.6e-157 523.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EPE32948.1 - 1.6e-09 37.7 0.0 4.9e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EPE32948.1 - 5.5e-07 29.5 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Utp8 PF10395.4 EPE32949.1 - 0.00021 19.7 0.7 0.0033 15.8 0.4 2.5 2 1 0 2 2 2 1 Utp8 family AAA PF00004.24 EPE32950.1 - 2.3e-07 31.0 1.5 2.5e-06 27.7 1.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EPE32950.1 - 4.7e-07 28.8 0.2 0.0041 15.8 0.0 3.3 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EPE32950.1 - 0.0023 18.0 0.1 0.015 15.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE32950.1 - 0.003 18.3 0.5 0.016 16.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EPE32950.1 - 0.0062 16.5 0.1 0.058 13.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EPE32950.1 - 0.033 13.9 0.0 0.089 12.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EPE32950.1 - 0.033 14.1 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EPE32950.1 - 0.066 11.9 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 EPE32950.1 - 0.11 12.3 0.0 0.4 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Catalase PF00199.14 EPE32951.1 - 2.7e-178 592.5 2.0 3.1e-178 592.2 1.4 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EPE32951.1 - 2e-11 43.5 0.1 5e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive bZIP_1 PF00170.16 EPE32952.1 - 6.1e-11 42.1 9.8 1.1e-10 41.3 6.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPE32952.1 - 3.3e-06 26.8 11.8 3.3e-06 26.8 8.2 1.5 2 0 0 2 2 2 1 Basic region leucine zipper Tmemb_cc2 PF10267.4 EPE32952.1 - 0.029 12.9 2.0 0.036 12.6 1.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF3395 PF11875.3 EPE32952.1 - 0.56 9.8 5.0 1 9.0 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) SDA1 PF05285.7 EPE32953.1 - 4.1e-94 315.4 44.7 6.5e-94 314.8 25.6 2.4 3 0 0 3 3 3 2 SDA1 NUC130_3NT PF08158.7 EPE32953.1 - 3.5e-22 78.4 0.3 1.2e-21 76.7 0.0 2.2 2 0 0 2 2 2 1 NUC130/3NT domain PRCC PF10253.4 EPE32954.1 - 0.072 13.7 2.3 0.093 13.4 1.6 1.0 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting AA_permease_2 PF13520.1 EPE32956.1 - 3e-41 141.3 52.0 2.4e-40 138.3 36.1 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE32956.1 - 8.2e-25 87.0 47.3 8.5e-24 83.7 32.7 2.2 1 1 0 1 1 1 1 Amino acid permease SGL PF08450.7 EPE32957.1 - 0.0019 17.6 0.0 0.01 15.2 0.0 2.1 3 0 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region ADH_zinc_N PF00107.21 EPE32958.1 - 2.5e-12 46.4 0.0 4.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE32958.1 - 4.9e-08 32.6 0.0 8.5e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PHP_C PF13263.1 EPE32958.1 - 0.12 11.9 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 PHP-associated WD40 PF00400.27 EPE32961.1 - 7.4e-62 203.1 28.2 1.1e-10 40.9 0.1 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.28 EPE32961.1 - 6e-13 48.0 1.6 2.6e-12 46.0 0.3 2.3 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.2 EPE32961.1 - 1.3e-12 47.2 0.4 2.6e-12 46.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EPE32961.1 - 3e-10 38.8 14.4 0.09 10.8 0.5 6.0 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPE32961.1 - 0.0024 16.7 0.9 0.9 8.2 0.3 3.2 2 1 0 2 2 2 1 Nup133 N terminal like PRANC PF09372.5 EPE32961.1 - 0.05 13.5 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Fungal_trans_2 PF11951.3 EPE32962.1 - 6.2e-05 21.7 0.1 0.00013 20.6 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 EPE32963.1 - 6.6e-26 90.3 0.2 1.9e-25 88.9 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE32963.1 - 7.5e-13 49.4 0.0 1.6e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE32963.1 - 7.4e-06 25.6 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 EPE32963.1 - 0.001 18.6 1.1 0.0015 18.1 0.3 1.6 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase APG17 PF04108.7 EPE32964.1 - 5.4e-118 394.3 1.5 6.4e-118 394.1 1.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 AF0941-like PF14591.1 EPE32964.1 - 0.011 15.7 0.7 0.011 15.7 0.5 3.3 4 1 0 4 4 4 0 AF0941-like HisKA PF00512.20 EPE32964.1 - 0.15 12.0 1.7 4.8 7.2 0.0 3.8 4 1 1 5 5 5 0 His Kinase A (phospho-acceptor) domain AATF-Che1 PF13339.1 EPE32964.1 - 0.4 10.8 7.5 1.5 9.0 0.3 3.5 2 2 0 2 2 2 0 Apoptosis antagonizing transcription factor Fib_alpha PF08702.5 EPE32964.1 - 1.7 8.7 10.1 1.5 8.9 0.6 4.1 3 3 1 4 4 4 0 Fibrinogen alpha/beta chain family Ribosomal_L4 PF00573.17 EPE32965.1 - 0.27 10.6 3.0 11 5.4 2.2 2.2 2 0 0 2 2 2 0 Ribosomal protein L4/L1 family Exo_endo_phos PF03372.18 EPE32967.1 - 2.7e-09 37.3 0.3 3.1e-09 37.1 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EPE32967.1 - 0.00062 19.3 0.0 0.004 16.7 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Fungal_trans PF04082.13 EPE32968.1 - 1.3e-07 30.7 0.0 2.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GpcrRhopsn4 PF10192.4 EPE32968.1 - 0.063 12.4 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain Serglycin PF04360.7 EPE32968.1 - 0.56 9.9 5.2 1.1 8.9 3.1 1.9 2 0 0 2 2 2 0 Serglycin Tyrosinase PF00264.15 EPE32969.1 - 5.8e-56 190.1 1.3 8.5e-56 189.5 0.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_M16 PF00675.15 EPE32970.1 - 1.4e-31 109.2 0.7 1.4e-31 109.2 0.5 2.3 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPE32970.1 - 2.4e-29 102.3 0.0 1.5e-17 63.8 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain TIP41 PF04176.8 EPE32972.1 - 2.5e-77 258.2 0.5 3e-77 257.9 0.3 1.1 1 0 0 1 1 1 1 TIP41-like family DUF3979 PF13141.1 EPE32972.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) Pkinase PF00069.20 EPE32973.1 - 5.3e-71 238.8 0.0 7e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE32973.1 - 5e-42 143.7 0.0 6.8e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE32973.1 - 3.9e-06 26.0 0.0 1.2e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPE32973.1 - 0.002 17.2 0.0 0.0051 15.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPE32973.1 - 0.013 14.8 0.1 0.032 13.5 0.0 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EPE32973.1 - 0.063 12.6 0.0 0.22 10.8 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Peptidase_M76 PF09768.4 EPE32974.1 - 9.9e-70 233.4 3.4 1.2e-69 233.1 2.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EPE32974.1 - 0.0014 18.3 4.1 0.0032 17.1 2.4 1.9 1 1 0 1 1 1 1 SprT-like family Tox-MPTase2 PF15638.1 EPE32974.1 - 0.059 12.8 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Peptidase_MA_2 PF13485.1 EPE32974.1 - 0.071 13.1 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily AA_kinase PF00696.23 EPE32975.1 - 3.4e-39 134.8 1.9 5.2e-39 134.2 1.3 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EPE32975.1 - 7.8e-14 51.1 1.9 1.5e-13 50.2 0.2 2.2 2 0 0 2 2 2 1 PUA domain Pkinase PF00069.20 EPE32977.1 - 8.9e-37 126.6 0.0 1.6e-36 125.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE32977.1 - 1.8e-17 63.3 0.1 8.6e-07 28.2 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase LANC_like PF05147.8 EPE32977.1 - 0.12 10.9 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Lipase_3 PF01764.20 EPE32979.1 - 3.3e-19 68.8 0.0 5.2e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EPE32979.1 - 0.073 12.9 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EPE32979.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein APH PF01636.18 EPE32980.1 - 2.1e-09 37.5 0.0 1e-08 35.2 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EPE32980.1 - 0.00034 19.3 0.0 0.00051 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EPE32980.1 - 0.003 16.7 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EPE32980.1 - 0.024 14.1 0.0 0.056 12.9 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase peroxidase PF00141.18 EPE32983.1 - 7e-47 159.8 0.0 9.7e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase VIT1 PF01988.14 EPE32984.1 - 0.027 13.9 0.3 0.038 13.4 0.2 1.2 1 0 0 1 1 1 0 VIT family ATP_synt_H PF05493.8 EPE32984.1 - 0.58 10.2 4.8 1.3 9.1 3.3 1.6 1 0 0 1 1 1 0 ATP synthase subunit H Pkinase PF00069.20 EPE32985.1 - 8.1e-32 110.3 0.0 1.3e-18 67.0 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EPE32985.1 - 1e-17 64.0 0.0 2.4e-15 56.2 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase CBM_21 PF03370.8 EPE32986.1 - 5.7e-29 100.3 0.2 1.4e-28 99.1 0.1 1.7 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit DUF948 PF06103.6 EPE32986.1 - 1.7 8.5 9.1 1.7 8.5 0.5 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.6 EPE32986.1 - 6 6.7 14.5 23 4.8 0.3 4.1 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_S8 PF00082.17 EPE32989.1 - 2.4e-09 36.7 0.2 2.4e-09 36.7 0.1 2.9 3 1 0 3 3 3 2 Subtilase family UCH PF00443.24 EPE32990.1 - 1.3e-76 257.3 0.0 9.4e-76 254.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPE32990.1 - 3.2e-16 59.6 0.0 8e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EPE32990.1 - 8.3e-12 45.3 0.1 6.7e-11 42.4 0.0 2.6 2 0 0 2 2 2 1 DUSP domain BCS1_N PF08740.6 EPE32991.1 - 1.7e-53 180.9 0.2 1.7e-53 180.9 0.2 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EPE32991.1 - 9.4e-18 64.6 0.0 5.3e-16 59.0 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE32991.1 - 0.0023 18.7 5.1 0.0079 17.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EPE32991.1 - 0.003 17.1 1.2 0.03 13.8 1.4 2.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPE32991.1 - 0.0058 15.7 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPE32991.1 - 0.0059 16.3 0.0 0.036 13.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EPE32991.1 - 0.0074 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EPE32991.1 - 0.01 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.1 EPE32991.1 - 0.026 14.4 0.0 0.073 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain CFIA_Pcf11 PF11526.3 EPE32991.1 - 0.072 13.2 0.5 0.072 13.2 0.4 2.5 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 ABC_tran PF00005.22 EPE32991.1 - 0.1 12.8 0.2 2.5 8.3 0.0 2.9 2 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 EPE32991.1 - 0.15 11.8 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RNase_H2-Ydr279 PF09468.5 EPE32991.1 - 4.4 6.4 10.7 43 3.1 6.1 2.4 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) RXT2_N PF08595.6 EPE32991.1 - 5.6 6.7 12.6 5.3 6.8 0.4 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal CBM_21 PF03370.8 EPE32993.1 - 6.9e-36 122.6 1.8 1.3e-35 121.7 1.2 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit BolA PF01722.13 EPE32994.1 - 3.9e-15 55.5 0.0 5.7e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Epimerase PF01370.16 EPE32995.1 - 1.8e-22 79.9 0.0 2.5e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE32995.1 - 1.1e-07 30.8 0.0 1.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPE32995.1 - 7.2e-07 29.2 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EPE32995.1 - 0.00043 20.3 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPE32995.1 - 0.0067 15.3 0.0 0.44 9.4 0.0 2.3 1 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EPE32995.1 - 0.0084 15.0 0.0 0.0098 14.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EPE32995.1 - 0.098 12.3 0.0 0.31 10.6 0.0 2.0 1 1 0 1 1 1 0 KR domain F_bP_aldolase PF01116.15 EPE32996.1 - 4.3e-77 259.0 0.0 4.9e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Glyco_hydro_cc PF11790.3 EPE32997.1 - 4.2e-60 203.1 4.7 4.9e-60 202.9 3.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Velvet PF11754.3 EPE32998.1 - 3.8e-06 26.6 0.0 4.4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Velvet factor tRNA-synt_1d PF00750.14 EPE32999.1 - 1.8e-82 277.0 4.8 3.5e-82 276.0 3.3 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EPE32999.1 - 9.2e-29 99.8 0.5 2.9e-28 98.2 0.3 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EPE32999.1 - 4.2e-09 36.8 0.0 4.9e-08 33.3 0.0 2.7 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain DUF1708 PF08101.6 EPE32999.1 - 0.14 10.9 2.3 0.74 8.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1708) HSP20 PF00011.16 EPE33000.1 - 4.4e-09 36.1 0.1 2.9e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family PIH1 PF08190.7 EPE33000.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 ACC_central PF08326.7 EPE33001.1 - 3.1e-264 878.4 0.0 3.8e-264 878.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EPE33001.1 - 1.1e-179 597.9 0.0 1.7e-179 597.2 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EPE33001.1 - 9e-51 172.1 0.0 1.6e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EPE33001.1 - 6e-24 84.2 0.1 1.2e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EPE33001.1 - 2.2e-21 75.8 0.0 1.3e-19 70.1 0.0 3.2 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EPE33001.1 - 4.7e-16 58.1 0.1 1.2e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EPE33001.1 - 2.9e-10 40.2 0.0 7.5e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPE33001.1 - 3.8e-07 29.1 0.0 1.7e-05 23.7 0.0 2.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EPE33001.1 - 0.0036 16.7 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EPE33001.1 - 0.013 15.4 0.0 0.043 13.6 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain HET PF06985.6 EPE33002.1 - 6.2e-18 65.2 0.1 6.2e-18 65.2 0.0 2.1 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) zf-Apc11 PF12861.2 EPE33002.1 - 0.074 12.8 3.2 0.16 11.8 2.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MFS_1 PF07690.11 EPE33003.1 - 1.9e-28 99.1 25.8 1.9e-28 99.1 17.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EPE33003.1 - 1.7 6.6 8.7 2.3 6.1 0.3 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family AJAP1_PANP_C PF15298.1 EPE33004.1 - 0.066 13.0 0.1 0.096 12.5 0.1 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus TauD PF02668.11 EPE33005.1 - 3e-16 59.8 0.0 4.7e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.13 EPE33006.1 - 0.0011 18.7 7.7 0.0021 17.9 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_10 PF13673.1 EPE33007.1 - 9e-06 25.8 0.0 0.0077 16.3 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE33007.1 - 1.6e-05 24.7 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EPE33007.1 - 5.4e-05 23.0 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPE33007.1 - 0.0044 17.1 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE33007.1 - 0.007 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.13 EPE33007.1 - 0.033 13.4 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family FR47 PF08445.5 EPE33007.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein TSSC4 PF15264.1 EPE33007.1 - 0.11 12.9 0.9 0.21 12.0 0.2 1.7 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 PEX11 PF05648.9 EPE33008.1 - 0.0016 17.7 0.8 0.08 12.1 0.0 2.3 3 0 0 3 3 3 2 Peroxisomal biogenesis factor 11 (PEX11) RRM_1 PF00076.17 EPE33009.1 - 1.1e-57 191.5 0.0 3.6e-21 74.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE33009.1 - 7.1e-42 141.2 0.0 1e-13 51.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE33009.1 - 9.5e-30 102.2 0.0 1.4e-09 37.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPE33009.1 - 2.1e-06 27.3 0.1 0.013 15.2 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EPE33009.1 - 0.00015 21.4 0.0 3.3 7.5 0.0 3.3 2 1 1 3 3 3 2 Nup53/35/40-type RNA recognition motif zf-C2H2_4 PF13894.1 EPE33010.1 - 0.00076 19.6 18.9 0.26 11.6 1.9 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger MCPVI PF02993.9 EPE33012.1 - 0.089 12.9 7.8 0.15 12.1 5.4 1.5 1 0 0 1 1 1 0 Minor capsid protein VI DAG1 PF05454.6 EPE33014.1 - 0.1 11.7 0.6 0.17 11.0 0.4 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF2024 PF09630.5 EPE33014.1 - 0.11 12.1 0.9 0.2 11.3 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) SR-25 PF10500.4 EPE33014.1 - 4.6 6.6 8.5 7 6.0 5.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mpv17_PMP22 PF04117.7 EPE33015.1 - 1.1e-12 47.3 2.0 2.9e-11 42.8 1.1 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF3557 PF12078.3 EPE33015.1 - 0.00016 21.4 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3557) DUF1275 PF06912.6 EPE33015.1 - 0.027 13.6 0.7 2 7.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1275) Isochorismatase PF00857.15 EPE33017.1 - 7.6e-44 149.6 0.0 8.8e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family AA_permease_2 PF13520.1 EPE33018.1 - 3.8e-59 200.3 48.2 4.5e-59 200.0 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE33018.1 - 3e-25 88.5 42.6 4.1e-25 88.0 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease NUDE_C PF04880.8 EPE33019.1 - 7.4e-21 75.2 8.2 7.4e-21 75.2 5.7 3.6 2 1 0 3 3 1 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 EPE33019.1 - 0.00019 21.6 5.5 0.00019 21.6 3.8 3.8 2 1 2 4 4 4 1 Protein of unknown function (DUF904) IncA PF04156.9 EPE33019.1 - 0.066 12.8 31.8 0.11 12.1 8.5 2.9 2 1 1 3 3 3 0 IncA protein NPV_P10 PF05531.7 EPE33019.1 - 0.1 12.8 3.0 3.3 8.0 0.0 3.3 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 EPE33019.1 - 0.4 10.5 33.9 12 5.7 14.9 4.1 2 1 1 3 3 3 0 Tropomyosin like Rab5-bind PF09311.6 EPE33019.1 - 0.71 9.7 32.1 1.1 9.0 12.2 3.1 2 1 1 3 3 3 0 Rabaptin-like protein EAP30 PF04157.11 EPE33019.1 - 0.74 8.9 8.5 0.61 9.1 2.2 2.8 2 1 0 3 3 3 0 EAP30/Vps36 family Prefoldin_2 PF01920.15 EPE33019.1 - 1.6 8.4 32.9 0.24 11.1 3.1 5.3 2 1 3 5 5 5 0 Prefoldin subunit DUF3584 PF12128.3 EPE33019.1 - 3.5 4.8 23.9 6.1 4.0 16.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ERM PF00769.14 EPE33019.1 - 4.1 6.8 29.4 14 5.1 20.4 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF3138 PF11336.3 EPE33019.1 - 5.4 5.0 4.4 2.9 5.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) ATG16 PF08614.6 EPE33019.1 - 5.4 6.7 30.7 4.9 6.9 11.0 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Lectin_N PF03954.9 EPE33019.1 - 5.8 6.3 7.3 1.4 8.3 1.1 2.7 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain V_ATPase_I PF01496.14 EPE33019.1 - 6 4.5 21.2 3.4 5.4 8.0 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family GrpE PF01025.14 EPE33019.1 - 6.3 6.3 32.8 0.26 10.8 7.0 3.6 2 1 2 4 4 4 0 GrpE DUF1664 PF07889.7 EPE33019.1 - 7.2 6.4 7.7 4.9 6.9 1.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PIF1 PF05970.9 EPE33021.1 - 4.1e-62 210.2 0.9 3e-59 200.8 0.6 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EPE33021.1 - 6.3e-16 58.5 0.0 2.1e-15 56.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPE33021.1 - 1.8e-06 28.1 0.0 5.7e-06 26.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EPE33021.1 - 8.3e-05 22.2 0.2 0.00018 21.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EPE33021.1 - 0.00017 20.5 0.1 0.00037 19.4 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Herpes_Helicase PF02689.9 EPE33021.1 - 0.00019 19.3 0.1 0.0022 15.8 0.0 2.0 2 0 0 2 2 2 1 Helicase PhoH PF02562.11 EPE33021.1 - 0.00041 19.6 0.3 0.0046 16.2 0.0 2.6 3 0 0 3 3 3 1 PhoH-like protein AAA_16 PF13191.1 EPE33021.1 - 0.00042 20.3 0.1 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EPE33021.1 - 0.00056 20.1 0.1 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 EPE33021.1 - 0.00057 19.9 0.0 0.0035 17.4 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 EPE33021.1 - 0.0055 15.7 0.9 0.0084 15.1 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 EPE33021.1 - 0.0061 16.8 0.4 0.032 14.5 0.0 2.3 1 1 1 2 2 2 1 ABC transporter RNA_helicase PF00910.17 EPE33021.1 - 0.0098 16.0 0.0 0.033 14.3 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.1 EPE33021.1 - 0.018 14.5 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EPE33021.1 - 0.019 14.1 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.2 EPE33021.1 - 0.021 13.9 0.0 0.047 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 TrwB_AAD_bind PF10412.4 EPE33021.1 - 0.022 13.3 0.0 0.036 12.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF258 PF03193.11 EPE33021.1 - 0.028 13.5 0.2 0.053 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EPE33021.1 - 0.034 13.7 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EPE33021.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EPE33021.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 EPE33021.1 - 0.067 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ArgK PF03308.11 EPE33021.1 - 0.079 11.7 0.1 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein NB-ARC PF00931.17 EPE33021.1 - 0.093 11.5 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 EPE33021.1 - 0.1 12.2 0.2 1 9.0 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) YjeF_N PF03853.10 EPE33022.1 - 4.9e-34 117.3 0.0 7.6e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EPE33022.1 - 1.2e-09 38.5 0.7 1.2e-09 38.5 0.5 1.9 2 0 0 2 2 2 1 FDF domain APH PF01636.18 EPE33023.1 - 5.4e-09 36.1 0.0 7.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EPE33023.1 - 0.0015 17.7 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase zf-C3HC4_3 PF13920.1 EPE33024.1 - 1.5e-10 40.5 5.4 2.1e-10 40.0 3.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE33024.1 - 1.8e-09 37.2 7.3 2.8e-09 36.6 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPE33024.1 - 2.8e-08 33.2 9.7 4.4e-08 32.6 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE33024.1 - 7.9e-08 32.2 9.0 1.2e-07 31.6 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE33024.1 - 7.9e-06 25.5 8.4 1.2e-05 24.9 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_3 PF14369.1 EPE33024.1 - 5.8e-05 22.9 3.8 0.04 13.9 0.3 2.6 2 0 0 2 2 2 2 zinc-finger zf-C3HC4_4 PF15227.1 EPE33024.1 - 0.0017 18.2 9.1 0.0026 17.5 6.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EPE33024.1 - 0.029 13.9 4.5 0.058 12.9 3.1 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 EPE33024.1 - 0.14 11.7 7.6 0.47 10.0 5.1 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EPE33024.1 - 0.18 11.5 4.6 0.4 10.4 3.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EPE33024.1 - 0.24 11.5 6.3 0.67 10.0 4.4 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger FANCL_C PF11793.3 EPE33024.1 - 2.1 8.3 6.8 72 3.4 4.7 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 EPE33024.1 - 5.9 6.5 9.5 56 3.3 6.6 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Snapin_Pallidin PF14712.1 EPE33025.1 - 0.016 15.4 1.0 0.073 13.3 0.0 2.3 2 1 0 2 2 2 0 Snapin/Pallidin bZIP_1 PF00170.16 EPE33025.1 - 1 9.3 3.9 11 6.0 0.0 2.3 2 1 0 2 2 2 0 bZIP transcription factor DUF1188 PF06690.6 EPE33027.1 - 0.094 11.8 0.3 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Pox_P35 PF03213.9 EPE33027.1 - 0.19 10.6 0.8 0.19 10.6 0.5 1.1 1 0 0 1 1 1 0 Poxvirus P35 protein Hamartin PF04388.7 EPE33027.1 - 0.22 10.1 4.2 0.25 9.9 2.9 1.1 1 0 0 1 1 1 0 Hamartin protein Mnd1 PF03962.10 EPE33027.1 - 0.38 10.4 6.1 0.51 9.9 4.2 1.3 1 0 0 1 1 1 0 Mnd1 family DUF4398 PF14346.1 EPE33027.1 - 0.73 9.9 10.8 1.4 8.9 3.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) CCDC-167 PF15188.1 EPE33027.1 - 2.5 8.0 9.5 0.75 9.7 2.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SOBP PF15279.1 EPE33027.1 - 2.7 8.2 5.7 3.2 8.0 3.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PB1-F2 PF11986.3 EPE33028.1 - 0.012 15.6 1.0 0.35 10.9 0.2 2.4 2 0 0 2 2 2 0 Influenza A Proapoptotic protein QRPTase_C PF01729.14 EPE33028.1 - 0.039 13.4 0.2 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain NEMO PF11577.3 EPE33028.1 - 0.17 11.6 3.7 0.37 10.5 2.6 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Suc_Fer-like PF06999.7 EPE33030.1 - 5e-35 121.5 0.0 7.6e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like MFS_1 PF07690.11 EPE33031.1 - 6.6e-24 84.2 27.7 9.8e-24 83.7 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EPE33031.1 - 4.8e-05 21.9 2.5 4.8e-05 21.9 1.8 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein UCR_hinge PF02320.11 EPE33032.1 - 6.9e-26 89.9 9.3 1.2e-25 89.1 6.5 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Senescence_reg PF04520.8 EPE33032.1 - 0.12 12.8 6.3 0.17 12.3 4.3 1.3 1 0 0 1 1 1 0 Senescence regulator DUF4045 PF13254.1 EPE33032.1 - 0.18 11.0 6.8 0.2 10.9 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SCHIP-1 PF10148.4 EPE33032.1 - 0.22 10.8 2.3 0.28 10.5 1.6 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 CDC45 PF02724.9 EPE33032.1 - 0.35 8.8 10.6 0.39 8.6 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EPE33032.1 - 0.39 10.2 13.7 0.51 9.9 9.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 EPE33032.1 - 0.45 8.3 22.4 0.5 8.2 15.5 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EPE33032.1 - 0.53 8.7 21.9 0.59 8.5 15.2 1.0 1 0 0 1 1 1 0 Daxx Family HSP70 PF00012.15 EPE33032.1 - 0.78 7.5 9.1 0.95 7.2 6.3 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF1510 PF07423.6 EPE33032.1 - 0.92 8.8 15.8 1.1 8.5 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC27 PF09507.5 EPE33032.1 - 0.93 8.6 15.9 0.99 8.5 11.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pox_Ag35 PF03286.9 EPE33032.1 - 1.1 8.7 14.2 1.4 8.4 9.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Merozoite_SPAM PF07133.6 EPE33032.1 - 2.2 8.1 23.7 2.7 7.8 16.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Tim54 PF11711.3 EPE33032.1 - 2.5 6.6 9.0 2.7 6.4 6.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_3_Rpc31 PF11705.3 EPE33032.1 - 2.6 7.9 15.9 3.4 7.5 11.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 MIP-T3 PF10243.4 EPE33032.1 - 2.7 6.3 19.5 3.4 6.0 13.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SDA1 PF05285.7 EPE33032.1 - 2.7 7.1 19.3 3.1 6.9 13.4 1.1 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.7 EPE33032.1 - 4 7.2 14.9 4.6 7.0 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP1_TM PF14812.1 EPE33032.1 - 5.2 7.4 13.0 8.3 6.8 9.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF740 PF05340.7 EPE33032.1 - 7.7 4.7 12.8 8.8 4.5 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) SAPS PF04499.10 EPE33032.1 - 7.9 4.9 7.6 8.9 4.8 5.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.7 EPE33032.1 - 7.9 5.5 20.7 10 5.1 14.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-T PF15511.1 EPE33032.1 - 8.4 5.5 15.9 9.5 5.3 11.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pox_RNA_Pol_19 PF05320.7 EPE33032.1 - 8.8 6.0 11.0 12 5.5 7.7 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RRN3 PF05327.6 EPE33032.1 - 9.7 4.1 9.2 11 3.9 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 WWbp PF10349.4 EPE33033.1 - 1.1e-17 65.0 4.5 1.1e-17 65.0 3.1 2.2 2 0 0 2 2 2 1 WW-domain ligand protein hGDE_N PF14699.1 EPE33033.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme Vps36_ESCRT-II PF11605.3 EPE33033.1 - 0.13 12.0 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 MCPVI PF02993.9 EPE33033.1 - 1.9 8.6 3.9 7.5 6.6 1.0 2.1 2 0 0 2 2 2 0 Minor capsid protein VI Methyltransf_6 PF03737.10 EPE33035.1 - 9.3e-21 74.2 0.2 1.2e-20 73.8 0.1 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Drf_GBD PF06371.8 EPE33036.1 - 6.1e-19 68.1 0.7 2.9e-17 62.6 0.5 2.5 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Hydrophobin_2 PF06766.6 EPE33037.1 - 1.3e-07 31.1 5.4 1.8e-07 30.7 3.7 1.3 1 0 0 1 1 1 1 Fungal hydrophobin ZZ PF00569.12 EPE33038.1 - 0.00046 19.6 9.8 0.00079 18.9 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Prominin PF05478.6 EPE33039.1 - 0.095 10.2 6.6 0.12 9.8 3.5 2.0 2 0 0 2 2 2 0 Prominin YajC PF02699.10 EPE33042.1 - 0.0013 18.3 1.4 0.0017 18.0 0.1 1.8 2 0 0 2 2 2 1 Preprotein translocase subunit AAA_13 PF13166.1 EPE33042.1 - 0.042 12.3 4.7 0.057 11.8 3.3 1.1 1 0 0 1 1 1 0 AAA domain DUF912 PF06024.7 EPE33042.1 - 0.066 13.2 0.1 0.066 13.2 0.1 2.6 2 1 0 2 2 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 EPE33042.1 - 0.082 12.6 0.1 0.082 12.6 0.1 2.7 2 1 0 2 2 1 0 TMEM154 protein family 7TM_GPCR_Srw PF10324.4 EPE33042.1 - 0.12 11.4 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Sarcoglycan_2 PF05510.8 EPE33042.1 - 0.12 10.6 0.0 0.24 9.6 0.0 1.4 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon AIP3 PF03915.8 EPE33042.1 - 0.16 10.8 11.8 0.051 12.4 6.3 1.4 2 0 0 2 2 2 0 Actin interacting protein 3 Prominin PF05478.6 EPE33042.1 - 0.8 7.1 5.4 1.2 6.6 3.7 1.1 1 0 0 1 1 1 0 Prominin DNA_pol_viral_N PF00242.12 EPE33042.1 - 1.2 8.0 15.6 3.2 6.6 10.8 1.7 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Mnd1 PF03962.10 EPE33042.1 - 1.5 8.4 8.5 2.7 7.6 5.9 1.3 1 0 0 1 1 1 0 Mnd1 family DivIVA PF05103.8 EPE33042.1 - 6.5 6.8 26.4 2.6 8.1 14.9 2.6 1 1 1 2 2 2 0 DivIVA protein Neur_chan_memb PF02932.11 EPE33042.1 - 8.1 6.2 8.4 35 4.1 4.0 2.3 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-C2H2 PF00096.21 EPE33043.1 - 4.7e-07 29.7 14.4 0.00043 20.4 2.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE33043.1 - 1.6e-06 28.0 12.5 0.0057 16.9 1.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-UDP PF14569.1 EPE33043.1 - 0.23 11.2 1.3 0.52 10.1 0.9 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger Ogr_Delta PF04606.7 EPE33043.1 - 1.6 8.4 6.4 0.34 10.6 1.2 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DUF3129 PF11327.3 EPE33044.1 - 2.5e-25 89.3 11.4 2.5e-25 89.3 7.9 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) ABC_tran PF00005.22 EPE33045.1 - 1.5e-41 141.8 0.1 7.4e-20 71.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPE33045.1 - 1.9e-38 132.4 27.7 2.1e-22 79.8 9.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region T2SE PF00437.15 EPE33045.1 - 5e-13 48.5 0.1 1.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.14 EPE33045.1 - 2.6e-10 39.9 3.0 1.1e-05 24.7 0.2 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EPE33045.1 - 1.1e-09 38.0 0.6 0.00087 18.8 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_29 PF13555.1 EPE33045.1 - 4.2e-09 35.8 0.9 0.00055 19.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EPE33045.1 - 1.4e-08 35.3 1.4 2.5e-05 24.7 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPE33045.1 - 3.9e-08 33.4 0.1 0.012 15.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EPE33045.1 - 1e-07 32.2 9.6 0.0014 18.6 0.1 4.4 4 1 0 4 4 3 2 AAA domain AAA_17 PF13207.1 EPE33045.1 - 2e-07 31.8 0.1 0.046 14.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EPE33045.1 - 5.5e-07 29.5 0.1 0.013 15.3 0.1 2.9 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EPE33045.1 - 1.6e-06 28.0 0.0 0.0032 17.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EPE33045.1 - 1.7e-06 28.1 2.1 0.017 15.1 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 EPE33045.1 - 1.7e-06 28.3 0.1 0.096 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EPE33045.1 - 1.9e-06 27.5 0.4 0.035 13.5 0.2 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_25 PF13481.1 EPE33045.1 - 2.6e-06 26.9 0.2 0.022 14.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPE33045.1 - 2.8e-06 26.6 1.5 0.032 13.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_14 PF13173.1 EPE33045.1 - 1.7e-05 24.7 0.2 0.34 10.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 EPE33045.1 - 3.1e-05 23.8 0.5 0.014 15.1 0.1 2.5 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.1 EPE33045.1 - 3.9e-05 23.5 3.4 0.13 12.1 0.0 3.6 3 1 0 3 3 2 2 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 EPE33045.1 - 4.4e-05 23.2 0.7 0.058 13.1 0.0 2.4 2 0 0 2 2 2 2 NTPase AAA_19 PF13245.1 EPE33045.1 - 4.5e-05 23.1 0.5 0.0046 16.6 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 EPE33045.1 - 4.7e-05 22.5 0.1 0.15 11.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Arch_ATPase PF01637.13 EPE33045.1 - 7.9e-05 22.4 0.1 0.14 11.8 0.0 2.7 3 0 0 3 3 2 1 Archaeal ATPase Miro PF08477.8 EPE33045.1 - 0.00013 22.4 0.1 0.64 10.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 EPE33045.1 - 0.00013 21.6 1.1 0.5 10.0 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EPE33045.1 - 0.00016 21.3 0.9 0.25 11.0 0.1 2.8 2 0 0 2 2 2 2 NACHT domain cobW PF02492.14 EPE33045.1 - 0.00017 21.0 1.8 0.19 11.1 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.10 EPE33045.1 - 0.00021 20.0 0.2 0.0069 15.0 0.1 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein Viral_helicase1 PF01443.13 EPE33045.1 - 0.00024 20.6 0.8 0.35 10.3 0.1 2.7 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 EPE33045.1 - 0.00033 19.3 0.4 0.22 10.0 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 EPE33045.1 - 0.0012 18.4 0.1 1.2 8.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 EPE33045.1 - 0.0024 17.7 5.2 0.26 11.0 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 RNA_helicase PF00910.17 EPE33045.1 - 0.0032 17.6 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DAP3 PF10236.4 EPE33045.1 - 0.0039 16.1 0.7 0.6 8.9 0.1 2.6 3 0 0 3 3 2 1 Mitochondrial ribosomal death-associated protein 3 ABC_ATPase PF09818.4 EPE33045.1 - 0.0039 15.8 3.4 1.5 7.3 0.0 3.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class Guanylate_kin PF00625.16 EPE33045.1 - 0.0043 16.5 0.6 0.066 12.6 0.0 2.2 2 0 0 2 2 2 1 Guanylate kinase Mg_chelatase PF01078.16 EPE33045.1 - 0.0094 15.1 0.1 2.4 7.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MutS_V PF00488.16 EPE33045.1 - 0.0095 15.3 0.2 0.04 13.3 0.0 2.0 2 0 0 2 2 2 1 MutS domain V Pox_A32 PF04665.7 EPE33045.1 - 0.016 14.4 0.4 0.63 9.2 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.9 EPE33045.1 - 0.02 14.5 0.7 18 5.0 0.1 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 EPE33045.1 - 0.027 13.9 0.0 2.1 7.8 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA PF00004.24 EPE33045.1 - 0.028 14.6 0.2 3 8.0 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EPE33045.1 - 0.028 14.0 0.2 5.3 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA12 PF10443.4 EPE33045.1 - 0.04 12.4 0.6 0.61 8.5 0.0 2.3 2 0 0 2 2 2 0 RNA12 protein IstB_IS21 PF01695.12 EPE33045.1 - 0.04 13.3 0.2 11 5.4 0.0 3.0 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_11 PF13086.1 EPE33045.1 - 0.046 13.2 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.12 EPE33045.1 - 0.087 12.3 0.3 12 5.3 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.4 EPE33045.1 - 0.11 11.5 0.1 4.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.4 EPE33045.1 - 0.11 12.0 1.1 12 5.3 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EPE33045.1 - 0.12 11.3 0.2 2.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_28 PF13521.1 EPE33045.1 - 0.13 12.2 1.4 2.6 7.9 0.3 2.4 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 EPE33045.1 - 0.22 10.9 0.9 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.20 EPE33046.1 - 9.1e-18 64.7 0.1 1.4e-17 64.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE33046.1 - 5.1e-07 29.5 0.1 7.2e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE33046.1 - 1.2e-06 28.4 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase T2SE PF00437.15 EPE33046.1 - 0.068 12.0 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Ogr_Delta PF04606.7 EPE33048.1 - 0.41 10.3 2.4 1 9.1 1.7 1.7 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger zf-C2H2_4 PF13894.1 EPE33048.1 - 5.5 7.5 16.3 0.78 10.2 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger KTI12 PF08433.5 EPE33049.1 - 1.2e-73 247.7 0.0 1.5e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EPE33049.1 - 7.6e-06 25.8 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE33049.1 - 0.00053 20.7 0.0 0.0011 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPE33049.1 - 0.001 19.3 0.0 0.0024 18.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPE33049.1 - 0.018 14.9 0.0 0.063 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EPE33051.1 - 5.2e-133 443.5 4.2 6.2e-133 443.2 2.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EPE33051.1 - 8.5e-15 54.4 1.9 2.3e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EPE33051.1 - 6.7e-05 22.3 0.0 0.00029 20.3 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EPE33051.1 - 0.0011 19.4 0.8 2 8.9 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EPE33051.1 - 0.01 15.3 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EPE33051.1 - 0.012 14.7 5.2 0.21 10.6 0.2 2.6 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPE33051.1 - 0.02 14.3 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPE33051.1 - 0.048 13.6 0.0 7 6.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mog1 PF04603.7 EPE33051.1 - 0.073 13.0 0.5 0.37 10.7 0.0 2.2 2 1 1 3 3 3 0 Ran-interacting Mog1 protein Ly49 PF08391.5 EPE33052.1 - 0.2 11.8 2.2 0.27 11.3 1.5 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF543 PF04418.7 EPE33053.1 - 3e-27 94.3 0.0 3.6e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.4 EPE33054.1 - 2.1e-59 200.8 1.8 2.1e-59 200.8 1.2 2.3 2 0 0 2 2 2 1 Urb2/Npa2 family DUF4255 PF14065.1 EPE33054.1 - 0.026 13.9 0.4 3.5 7.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4255) DUF905 PF06006.7 EPE33054.1 - 0.031 13.6 0.5 0.09 12.1 0.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Abhydrolase_5 PF12695.2 EPE33055.1 - 8.6e-10 38.5 0.1 1.2e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE33055.1 - 1.4e-08 34.9 0.3 1.3e-07 31.7 0.2 1.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EPE33055.1 - 6.7e-07 28.2 0.0 9.8e-07 27.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EPE33055.1 - 1.5e-06 27.9 0.1 3e-06 26.9 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EPE33055.1 - 0.00026 19.8 0.0 0.00036 19.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EPE33055.1 - 0.11 11.7 0.0 2.8 7.1 0.1 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family Sec10 PF07393.6 EPE33056.1 - 3.5e-160 534.5 0.0 4.4e-160 534.2 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 EPE33056.1 - 1.4e-06 27.7 0.1 3.6e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE33056.1 - 7e-06 25.6 0.2 6.8e-05 22.5 0.1 2.4 2 0 0 2 2 2 1 F-box-like DUF3812 PF12757.2 EPE33057.1 - 7.7e-37 126.0 11.3 7.7e-37 126.0 7.8 4.5 3 1 1 4 4 4 1 Protein of unknown function (DUF3812) Y_phosphatase3 PF13350.1 EPE33058.1 - 1.1e-26 93.9 0.3 4e-25 88.9 0.2 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EPE33058.1 - 4.9e-06 25.9 0.0 1.5e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EPE33058.1 - 0.0011 18.5 0.3 0.069 12.7 0.0 2.5 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPE33058.1 - 0.0027 17.0 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3C PF13348.1 EPE33058.1 - 0.0047 17.0 0.1 0.0093 16.0 0.1 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Myotub-related PF06602.9 EPE33058.1 - 0.0054 15.5 0.2 0.01 14.6 0.1 1.6 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain zf-RING_2 PF13639.1 EPE33059.1 - 1.6e-06 27.8 11.2 1.6e-06 27.8 7.7 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EPE33059.1 - 0.00049 19.7 10.0 0.00049 19.7 6.9 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE33059.1 - 0.002 17.7 12.0 0.002 17.7 8.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EPE33059.1 - 0.11 12.0 10.1 0.38 10.3 5.6 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3015 PF11220.3 EPE33059.1 - 0.12 12.0 0.1 2.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) zf-C3HC4_2 PF13923.1 EPE33059.1 - 1.1 9.3 19.0 0.13 12.3 8.0 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ABC_tran PF00005.22 EPE33060.1 - 6.6e-48 162.4 0.1 1.8e-26 93.0 0.0 3.2 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPE33060.1 - 8.5e-45 153.2 37.6 1.2e-24 87.1 11.3 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EPE33060.1 - 9.2e-07 29.1 0.8 0.83 9.5 0.1 4.5 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EPE33060.1 - 6.4e-06 26.1 0.0 0.11 12.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EPE33060.1 - 1.5e-05 24.4 1.2 0.036 13.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EPE33060.1 - 2.1e-05 24.9 0.4 0.11 12.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EPE33060.1 - 2.8e-05 24.1 0.3 0.063 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EPE33060.1 - 3.3e-05 23.2 3.0 0.092 11.9 0.3 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EPE33060.1 - 0.00042 19.5 0.3 0.46 9.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EPE33060.1 - 0.001 18.2 0.2 0.42 9.6 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_22 PF13401.1 EPE33060.1 - 0.0027 17.8 2.2 9.3 6.4 0.0 4.1 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.12 EPE33060.1 - 0.0033 17.2 2.4 0.13 12.0 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_17 PF13207.1 EPE33060.1 - 0.0066 17.2 3.9 5.4 7.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPE33060.1 - 0.0067 15.8 0.1 0.66 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EPE33060.1 - 0.01 15.3 0.3 1.5 8.1 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 EPE33060.1 - 0.01 14.6 1.1 1.7 7.3 0.0 2.4 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 EPE33060.1 - 0.026 13.9 0.1 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EPE33060.1 - 0.03 13.9 0.9 6.3 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPE33060.1 - 0.094 12.4 0.8 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 EPE33060.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.6 4 0 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.12 EPE33060.1 - 0.72 9.3 2.6 13 5.2 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 EPE33060.1 - 3 7.6 10.6 0.2 11.4 0.1 2.9 3 0 0 3 3 2 0 Dynamin family Pkinase PF00069.20 EPE33061.1 - 1.5e-66 224.2 0.0 1.8e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE33061.1 - 5.4e-33 114.1 0.0 7.2e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE33061.1 - 0.0014 17.6 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3404 PF11884.3 EPE33061.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) Frag1 PF10277.4 EPE33062.1 - 4.1e-45 153.8 16.9 4.8e-45 153.6 11.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family NfeD PF01957.13 EPE33062.1 - 0.00057 20.0 2.7 0.52 10.4 1.0 2.4 1 1 1 2 2 2 2 NfeD-like C-terminal, partner-binding TrbC PF04956.8 EPE33062.1 - 0.012 15.6 1.1 0.012 15.6 0.7 1.9 2 0 0 2 2 2 0 TrbC/VIRB2 family Dispanin PF04505.7 EPE33062.1 - 0.05 13.1 0.1 0.19 11.3 0.0 2.1 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Pox_A14 PF05767.7 EPE33062.1 - 2.5 8.1 7.6 0.21 11.5 0.2 2.5 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 SNF2_N PF00176.18 EPE33063.1 - 2.3e-55 187.4 0.2 4.7e-55 186.4 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 EPE33063.1 - 7.8e-08 31.8 7.3 1.5e-07 30.9 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE33063.1 - 1.2e-07 31.2 6.5 2.2e-07 30.4 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE33063.1 - 1.9e-07 30.7 9.0 3.6e-07 29.9 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE33063.1 - 2.9e-06 27.2 9.1 5.7e-06 26.2 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE33063.1 - 1.5e-05 24.6 7.8 2.7e-05 23.8 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPE33063.1 - 0.0019 17.8 2.9 0.0075 15.9 2.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EPE33063.1 - 0.0023 18.0 9.5 0.0066 16.5 6.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger Helicase_C PF00271.26 EPE33063.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 EPE33063.1 - 0.017 14.9 7.5 0.042 13.7 5.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 EPE33063.1 - 0.023 14.4 1.0 0.055 13.2 0.7 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 EPE33063.1 - 0.032 13.7 3.4 0.074 12.6 2.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 EPE33063.1 - 0.21 11.0 5.4 0.55 9.7 3.8 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.1 EPE33063.1 - 8.5 6.0 10.0 1.6 8.3 4.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain p450 PF00067.17 EPE33065.1 - 1.1e-58 198.8 0.0 1.4e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EPE33066.1 - 5.7e-38 130.6 0.0 8.6e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Band_7 PF01145.20 EPE33067.1 - 1e-24 87.4 2.0 1.5e-24 86.8 1.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family DLH PF01738.13 EPE33068.1 - 8.2e-29 100.4 0.0 9.6e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPE33068.1 - 1.8e-08 34.2 0.0 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE33068.1 - 0.024 13.8 0.0 0.07 12.3 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EPE33068.1 - 0.14 11.5 0.0 1.2 8.4 0.0 2.0 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Epimerase PF01370.16 EPE33069.1 - 3.2e-11 43.1 0.1 6.7e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPE33069.1 - 1.2e-10 41.0 0.4 1.7e-10 40.5 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EPE33069.1 - 5.3e-07 29.9 0.2 3e-06 27.5 0.1 2.2 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EPE33069.1 - 1.4e-05 23.9 0.4 0.029 13.0 0.3 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPE33069.1 - 0.022 13.7 0.0 0.063 12.2 0.0 1.7 3 0 0 3 3 3 0 Male sterility protein DapB_N PF01113.15 EPE33069.1 - 0.031 14.2 0.1 0.071 13.0 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 EPE33069.1 - 0.051 14.1 0.1 0.099 13.1 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Fungal_trans_2 PF11951.3 EPE33070.1 - 6.9e-07 28.1 0.1 1.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Grp1_Fun34_YaaH PF01184.14 EPE33071.1 - 2.8e-26 92.1 23.6 6.3e-26 90.9 16.4 1.5 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family Ran_BP1 PF00638.13 EPE33072.1 - 7.4e-16 58.3 0.5 2.7e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 RanBP1 domain Yip1 PF04893.12 EPE33073.1 - 5.5e-15 55.2 11.0 7.9e-15 54.7 7.6 1.4 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EPE33073.1 - 1.2 8.7 10.9 2.7 7.6 7.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) PAS_3 PF08447.6 EPE33074.1 - 3.6e-13 49.4 0.1 3.3e-08 33.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EPE33074.1 - 4.2e-11 43.1 0.0 5.5e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EPE33074.1 - 1.5e-08 34.3 0.0 0.00049 19.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 EPE33074.1 - 2.8e-05 24.0 0.0 0.0002 21.2 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EPE33074.1 - 8e-05 22.6 0.0 0.041 13.9 0.0 3.3 3 0 0 3 3 3 1 PAS fold WD40 PF00400.27 EPE33075.1 - 6e-22 76.6 5.7 2.9e-09 36.4 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Thioredoxin PF00085.15 EPE33076.1 - 1.6e-44 149.7 0.0 3.2e-25 87.8 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EPE33076.1 - 8.3e-12 45.2 0.0 3e-06 27.1 0.0 4.3 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EPE33076.1 - 2.7e-09 37.2 2.0 0.031 14.4 0.1 4.7 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPE33076.1 - 1.2e-07 31.7 0.0 0.00059 19.9 0.0 4.0 3 1 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 EPE33076.1 - 0.00047 20.0 0.0 0.85 9.5 0.0 2.9 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EPE33076.1 - 0.00088 19.2 0.6 0.0032 17.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 EPE33076.1 - 0.029 14.0 1.1 0.19 11.4 0.0 2.7 3 0 0 3 3 3 0 AhpC/TSA family Thioredoxin_9 PF14595.1 EPE33076.1 - 0.075 12.6 0.7 2.9 7.4 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin Tyr-DNA_phospho PF06087.7 EPE33077.1 - 4.3e-134 447.4 0.0 5e-134 447.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EPE33077.1 - 5.1e-05 23.0 0.2 0.064 13.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain ACBP PF00887.14 EPE33078.1 - 2.3e-23 81.6 0.5 2.6e-23 81.4 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF573 PF04504.9 EPE33078.1 - 0.039 14.2 0.2 0.063 13.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF573 DUF1436 PF07262.6 EPE33078.1 - 0.15 11.5 0.3 0.24 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1436) MOSC PF03473.12 EPE33079.1 - 3.9e-18 65.1 0.0 7.4e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EPE33079.1 - 1.2e-11 44.3 0.0 2.5e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain PQQ_3 PF13570.1 EPE33080.1 - 0.26 11.6 1.7 3.4 8.0 0.2 3.2 2 0 0 2 2 2 0 PQQ-like domain 4HBT PF03061.17 EPE33081.1 - 1.3e-13 50.8 0.1 2.4e-13 49.9 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.1 EPE33081.1 - 0.0017 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily FA_desaturase PF00487.19 EPE33082.1 - 2.6e-19 69.6 10.9 2.6e-19 69.6 7.6 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EPE33082.1 - 1.6e-16 59.8 0.0 3.6e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EII-Sor PF03609.9 EPE33082.1 - 0.15 11.2 2.2 3.6 6.7 0.2 2.2 2 0 0 2 2 2 0 PTS system sorbose-specific iic component Xan_ur_permease PF00860.15 EPE33083.1 - 4.4e-65 219.6 41.6 1.2e-63 214.9 28.8 2.1 1 1 0 1 1 1 1 Permease family SMC_N PF02463.14 EPE33084.1 - 8.9e-71 237.6 0.0 4.9e-70 235.1 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPE33084.1 - 1.4e-21 76.7 2.8 2.1e-21 76.0 0.1 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPE33084.1 - 6.3e-12 46.0 4.9 3.7e-05 23.8 0.6 3.6 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EPE33084.1 - 1.9e-11 44.6 13.3 1.9e-11 44.6 9.2 6.2 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 EPE33084.1 - 0.0008 18.8 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EPE33084.1 - 0.052 13.8 0.0 0.052 13.8 0.0 6.1 4 2 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 EPE33084.1 - 0.075 12.1 34.1 0.22 10.6 1.0 6.2 3 2 4 7 7 7 0 Reovirus sigma C capsid protein Fungal_trans_2 PF11951.3 EPE33086.1 - 1.2e-14 53.7 3.0 2.1e-14 52.9 2.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE33086.1 - 1.5e-08 34.3 9.1 2.6e-08 33.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 EPE33086.1 - 0.063 13.2 0.1 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat NOT2_3_5 PF04153.13 EPE33087.1 - 5.7e-33 113.6 1.1 1.2e-32 112.6 0.7 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CUE PF02845.11 EPE33088.1 - 5.2e-13 48.1 0.0 8.2e-13 47.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain ketoacyl-synt PF00109.21 EPE33089.1 - 9.6e-59 198.9 1.4 1e-57 195.5 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EPE33089.1 - 9.1e-34 115.8 0.6 9.1e-34 115.8 0.4 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EPE33089.1 - 2e-06 27.0 0.1 7e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF3328 PF11807.3 EPE33090.1 - 3.4e-34 118.4 0.2 5e-34 117.8 0.1 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PhyH PF05721.8 EPE33092.1 - 2.9e-15 56.8 0.0 4e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EPE33092.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase zf-CHCC PF10276.4 EPE33093.1 - 3.1e-15 55.7 1.6 4.7e-15 55.1 1.1 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 EPE33093.1 - 0.06 13.0 0.6 0.12 12.0 0.1 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb GAGA_bind PF06217.7 EPE33094.1 - 0.013 15.4 3.3 0.023 14.6 2.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family SR-25 PF10500.4 EPE33094.1 - 0.015 14.7 15.0 0.013 15.0 8.4 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MPP6 PF10175.4 EPE33094.1 - 0.017 15.4 5.9 3.6 8.0 0.0 3.3 3 0 0 3 3 3 0 M-phase phosphoprotein 6 Cwf_Cwc_15 PF04889.7 EPE33094.1 - 0.59 9.8 20.7 0.78 9.4 14.4 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EPE33094.1 - 1.1 7.1 11.5 1.5 6.7 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EPE33094.1 - 3.3 7.0 11.7 5.6 6.2 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4612 PF15389.1 EPE33095.1 - 0.63 10.6 4.1 1.5 9.4 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) ADH_zinc_N PF00107.21 EPE33096.1 - 9e-29 99.6 0.4 1.8e-28 98.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE33096.1 - 1.5e-28 98.7 0.3 3.9e-28 97.3 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPE33096.1 - 4.9e-05 24.2 0.1 0.0001 23.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EPE33096.1 - 7.4e-05 22.3 0.1 0.00037 20.0 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 EPE33096.1 - 0.012 14.7 0.0 0.03 13.4 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EPE33096.1 - 0.014 15.5 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EPE33096.1 - 0.068 13.4 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 EPE33096.1 - 0.085 12.8 0.1 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 EPE33096.1 - 0.46 10.3 3.1 0.59 9.9 0.9 2.0 2 0 0 2 2 2 0 ThiF family TPP_enzyme_N PF02776.13 EPE33097.1 - 1.5e-37 128.6 0.0 3.2e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPE33097.1 - 1.8e-19 69.8 0.0 5.2e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EPE33097.1 - 2.8e-19 69.2 0.0 6.4e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Cyclin PF08613.6 EPE33098.1 - 1.6e-39 135.6 0.0 2.2e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin CLU_N PF15044.1 EPE33098.1 - 0.13 12.4 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term Peptidase_M24 PF00557.19 EPE33099.1 - 2.8e-54 183.8 0.1 3.8e-54 183.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EPE33099.1 - 4.1e-24 84.4 0.0 1e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF1615 PF07759.7 EPE33099.1 - 0.04 12.6 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) Sulfatase PF00884.18 EPE33100.1 - 2.2e-17 63.2 0.1 3.9e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EPE33100.1 - 2.9e-06 26.8 0.0 4.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EPE33100.1 - 0.0099 14.3 0.0 0.014 13.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 EPE33100.1 - 0.045 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily DHFR_1 PF00186.14 EPE33101.1 - 1e-35 122.7 0.0 1.6e-35 122.0 0.0 1.4 1 1 0 1 1 1 1 Dihydrofolate reductase DUF4181 PF13789.1 EPE33103.1 - 0.0068 16.3 1.2 0.014 15.3 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4181) Oxidored_q1 PF00361.15 EPE33103.1 - 0.035 13.3 4.3 0.056 12.7 3.0 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone/plastoquinone (complex I), various chains NnrS PF05940.7 EPE33103.1 - 0.12 11.3 6.7 0.18 10.7 4.6 1.1 1 0 0 1 1 1 0 NnrS protein DUF412 PF04217.8 EPE33103.1 - 0.16 11.7 1.4 0.4 10.4 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF412 DUF1516 PF07457.6 EPE33103.1 - 0.28 11.2 5.6 0.61 10.1 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) DUF4131 PF13567.1 EPE33103.1 - 0.46 9.8 2.4 0.8 9.0 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Cpn60_TCP1 PF00118.19 EPE33104.1 - 2.5e-134 448.5 4.8 2.9e-134 448.3 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HMG_box PF00505.14 EPE33105.1 - 7.9e-07 29.2 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPE33105.1 - 0.013 15.8 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 HMG-box domain DUF155 PF02582.9 EPE33106.1 - 3.1e-56 190.0 1.0 5.4e-56 189.2 0.4 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 PTRF_SDPR PF15237.1 EPE33108.1 - 0.0078 15.6 1.4 0.0086 15.5 1.0 1.0 1 0 0 1 1 1 1 PTRF/SDPR family Glyco_hydro_61 PF03443.9 EPE33109.1 - 2.4e-82 276.0 0.8 2.4e-82 276.0 0.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Ribosomal_60s PF00428.14 EPE33110.1 - 1.1 9.7 6.8 2.4 8.5 4.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein UPF0121 PF03661.8 EPE33113.1 - 1.8e-11 43.7 5.0 2.8e-11 43.0 3.4 1.2 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) CaATP_NAI PF12515.3 EPE33113.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain MFS_1 PF07690.11 EPE33114.1 - 9.3e-32 110.0 37.0 9.3e-32 110.0 25.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2970 PF11174.3 EPE33114.1 - 1.9 8.1 5.6 12 5.5 2.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Cupin_2 PF07883.6 EPE33115.1 - 0.047 13.1 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Septin PF00735.13 EPE33117.1 - 1.3e-122 408.2 0.1 1.3e-122 408.2 0.0 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EPE33117.1 - 9.8e-07 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPE33117.1 - 7.2e-05 22.0 0.3 0.00066 18.9 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EPE33117.1 - 0.00012 21.5 0.5 0.0086 15.5 0.0 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EPE33117.1 - 0.0002 21.6 2.1 0.029 14.6 0.0 2.8 3 0 0 3 3 3 1 ABC transporter AAA_10 PF12846.2 EPE33117.1 - 0.00094 18.7 1.3 0.002 17.6 0.9 1.8 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 EPE33117.1 - 0.0023 18.4 0.0 0.011 16.2 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EPE33117.1 - 0.0026 16.8 1.1 0.0077 15.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 EPE33117.1 - 0.0042 17.1 0.1 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EPE33117.1 - 0.0055 16.2 0.1 0.03 13.7 0.0 2.2 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EPE33117.1 - 0.0074 16.4 0.0 0.056 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ras PF00071.17 EPE33117.1 - 0.01 15.2 0.2 0.054 12.8 0.0 2.3 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.1 EPE33117.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 EPE33117.1 - 0.014 15.2 4.4 0.59 9.9 0.0 3.4 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 EPE33117.1 - 0.026 14.0 0.2 18 4.7 0.0 3.6 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein MobB PF03205.9 EPE33117.1 - 0.11 12.2 0.1 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EPE33117.1 - 0.14 12.3 0.2 0.87 9.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Exonuc_VII_L PF02601.10 EPE33117.1 - 0.16 11.0 6.6 0.32 10.1 4.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_24 PF13479.1 EPE33117.1 - 0.17 11.4 1.7 0.21 11.1 0.0 2.1 3 0 0 3 3 2 0 AAA domain YlqD PF11068.3 EPE33117.1 - 0.23 11.5 10.8 0.44 10.5 7.5 1.5 1 0 0 1 1 1 0 YlqD protein Strep_SA_rep PF06696.6 EPE33117.1 - 0.31 10.8 3.0 0.45 10.3 1.1 1.9 1 1 1 2 2 2 0 Streptococcal surface antigen repeat DUF87 PF01935.12 EPE33117.1 - 0.59 9.9 4.1 3.9 7.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_32 PF13654.1 EPE33117.1 - 1.1 7.8 13.9 0.62 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Phage_GPO PF05929.6 EPE33117.1 - 1.4 8.1 6.2 2.3 7.3 4.3 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.9 EPE33117.1 - 1.5 8.4 9.3 3.1 7.3 6.5 1.6 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EPE33117.1 - 5.6 4.6 9.9 9.4 3.9 6.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DLH PF01738.13 EPE33118.1 - 9.8e-27 93.6 0.0 1.3e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPE33118.1 - 1.4e-06 28.1 0.1 2.2e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE33118.1 - 0.0016 18.3 0.0 0.0046 16.8 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 EPE33118.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) RNA_pol_I_TF PF04090.7 EPE33119.1 - 8.6e-10 38.2 0.0 2.2e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor UDPGT PF00201.13 EPE33121.1 - 2.1e-14 52.9 0.0 5.4e-14 51.6 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 EPE33121.1 - 4.4e-05 23.2 0.0 9.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.11 EPE33121.1 - 0.0028 17.3 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EPE33121.1 - 0.015 14.4 0.0 0.097 11.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 1 Ubiq_cyt_C_chap PF03981.7 EPE33122.1 - 1.9e-37 128.2 0.7 2.6e-37 127.7 0.5 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Exo70 PF03081.10 EPE33123.1 - 1.2e-66 225.0 0.0 2.3e-66 224.0 0.0 1.5 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Caps_synth_GfcC PF06251.6 EPE33123.1 - 0.024 13.7 0.1 0.086 11.9 0.0 1.9 2 0 0 2 2 2 0 Capsule biosynthesis GfcC PLA2_B PF01735.13 EPE33124.1 - 2.2e-24 85.4 0.0 7.3e-24 83.7 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DSPc PF00782.15 EPE33125.1 - 2.2e-10 40.2 0.0 5.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPE33125.1 - 2.5e-05 23.7 0.0 4.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTEN_C2 PF10409.4 EPE33125.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Y_phosphatase3 PF13350.1 EPE33125.1 - 0.039 14.1 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EPE33125.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Abhydrolase_5 PF12695.2 EPE33126.1 - 3.7e-15 55.9 0.8 7.7e-15 54.9 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE33126.1 - 2.5e-13 50.4 0.8 3.9e-13 49.8 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EPE33126.1 - 4.8e-09 35.8 1.5 2.2e-08 33.6 1.1 1.9 1 1 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 EPE33126.1 - 2.3e-05 23.7 0.1 0.05 12.8 0.0 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EPE33126.1 - 0.0047 16.5 0.6 0.51 9.8 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EPE33126.1 - 0.0084 15.7 0.2 0.022 14.3 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EPE33126.1 - 0.013 14.4 0.2 0.021 13.7 0.1 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.13 EPE33126.1 - 0.018 14.3 0.1 3 7.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family HATPase_c PF02518.21 EPE33127.1 - 1.9e-23 82.2 0.3 1.7e-22 79.2 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE33127.1 - 3.6e-19 68.8 0.2 3.3e-17 62.4 0.1 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EPE33127.1 - 3.1e-13 49.4 0.0 8.7e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EPE33127.1 - 1.6e-09 38.0 0.0 1.8e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 EPE33127.1 - 0.00059 19.9 0.0 0.0072 16.4 0.0 2.6 3 0 0 3 3 3 1 GAF domain DUF3194 PF11419.3 EPE33127.1 - 0.18 12.0 0.1 0.51 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3194) DUF2375 PF09558.5 EPE33127.1 - 0.21 11.4 0.7 4.4 7.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2375) Fungal_trans PF04082.13 EPE33128.1 - 3.3e-12 45.8 0.1 5.4e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE33128.1 - 3.3e-06 26.9 14.2 5.3e-06 26.2 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCH PF02289.11 EPE33128.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Cyclohydrolase (MCH) ATG27 PF09451.5 EPE33129.1 - 1.4e-66 224.5 0.0 1.7e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EPE33129.1 - 0.00012 21.8 0.6 0.021 14.5 0.1 2.9 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat HLH PF00010.21 EPE33130.1 - 1.3e-11 44.0 1.1 6.5e-11 41.7 0.2 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RicinB_lectin_2 PF14200.1 EPE33130.1 - 3.8e-08 33.6 1.0 0.017 15.4 0.0 3.6 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EPE33130.1 - 0.053 13.5 2.6 4.1 7.4 0.0 3.5 3 1 1 4 4 4 0 Ricin-type beta-trefoil lectin domain DAO PF01266.19 EPE33131.1 - 4.9e-48 163.8 0.0 7.2e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans PF04082.13 EPE33131.1 - 1.7e-14 53.3 2.9 3.9e-14 52.1 2.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE33131.1 - 2.3e-07 30.6 9.5 4.9e-07 29.5 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_8 PF13450.1 EPE33131.1 - 0.0035 17.3 0.1 0.011 15.7 0.0 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EPE33131.1 - 0.055 12.0 0.2 0.22 10.1 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.19 EPE33131.1 - 0.058 12.2 0.2 0.2 10.4 0.1 1.8 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EPE33131.1 - 0.27 11.6 0.0 0.53 10.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Corona_nucleoca PF00937.13 EPE33132.1 - 0.057 12.3 1.1 0.054 12.4 0.8 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein HSP20 PF00011.16 EPE33133.1 - 2.2e-08 33.8 0.0 6.9e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 Hsp20/alpha crystallin family DUF2379 PF09543.5 EPE33133.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) F-box-like PF12937.2 EPE33134.1 - 0.0008 19.0 1.1 0.0025 17.5 0.8 1.9 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 EPE33134.1 - 0.045 13.9 9.3 15 6.3 0.0 6.6 7 0 0 7 7 7 0 Leucine rich repeat LRR_4 PF12799.2 EPE33134.1 - 0.077 12.6 11.4 5.3 6.7 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPE33134.1 - 0.29 11.3 11.5 66 4.1 0.1 6.3 6 2 0 6 6 6 0 Leucine Rich Repeat zf-H2C2_2 PF13465.1 EPE33135.1 - 2.5e-06 27.4 8.9 7.6e-05 22.7 1.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPE33135.1 - 6.5e-05 23.0 13.5 0.025 14.9 4.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE33135.1 - 0.0014 18.7 16.5 0.13 12.6 3.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPE33135.1 - 5.5 7.2 8.8 7.3 6.8 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Apt1 PF10351.4 EPE33136.1 - 5.1 5.8 8.2 5.5 5.7 5.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hexapep PF00132.19 EPE33137.1 - 6.2e-09 34.9 4.6 0.00014 21.1 0.5 2.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EPE33137.1 - 0.0002 21.4 0.0 0.0004 20.5 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EPE33137.1 - 0.0045 16.3 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.7 EPE33137.1 - 0.14 10.6 0.3 0.22 10.0 0.2 1.2 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.1 EPE33137.1 - 5.4 6.6 14.2 23 4.6 3.8 3.8 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase SRP19 PF01922.12 EPE33139.1 - 7.7e-29 100.1 0.0 1.4e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein ComK PF06338.6 EPE33140.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 ComK protein Pex14_N PF04695.8 EPE33140.1 - 0.21 11.6 1.2 0.22 11.5 0.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3446 PF11928.3 EPE33140.1 - 8.2 6.6 13.9 11 6.3 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) BCL_N PF04714.8 EPE33141.1 - 0.11 12.0 0.5 0.11 12.0 0.3 2.1 2 0 0 2 2 2 0 BCL7, N-terminal conserver region HIRA_B PF09453.5 EPE33141.1 - 0.19 11.3 0.9 0.39 10.3 0.6 1.5 1 0 0 1 1 1 0 HIRA B motif DUF4391 PF14335.1 EPE33141.1 - 0.23 10.8 8.3 0.028 13.7 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) MFS_1 PF07690.11 EPE33143.1 - 3.9e-41 140.9 35.9 5e-40 137.2 25.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE33143.1 - 1.3e-13 50.3 15.7 2.5e-12 46.1 11.1 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter Prefoldin_2 PF01920.15 EPE33144.1 - 1.7e-25 88.8 7.4 2.3e-25 88.3 5.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit FTA4 PF13093.1 EPE33144.1 - 0.0058 16.0 3.9 0.0071 15.8 2.7 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 MerR-DNA-bind PF09278.6 EPE33144.1 - 0.0059 16.9 1.3 0.0059 16.9 0.9 1.9 2 1 0 2 2 2 1 MerR, DNA binding DivIC PF04977.10 EPE33144.1 - 0.081 12.4 10.9 0.16 11.4 0.5 2.2 2 0 0 2 2 2 0 Septum formation initiator DNA_primase_lrg PF04104.9 EPE33144.1 - 0.16 11.2 1.4 0.18 11.0 0.2 1.6 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit AAA_23 PF13476.1 EPE33144.1 - 0.17 12.2 8.5 0.2 11.9 5.9 1.1 1 0 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.19 EPE33144.1 - 0.56 9.8 4.2 1.1 9.0 2.9 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Siah-Interact_N PF09032.6 EPE33144.1 - 0.79 9.8 9.2 0.65 10.1 1.6 2.5 2 0 0 2 2 2 0 Siah interacting protein, N terminal DUF1664 PF07889.7 EPE33144.1 - 1.2 8.9 4.2 1.7 8.4 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) APG6 PF04111.7 EPE33144.1 - 1.3 7.9 10.3 2.9 6.8 0.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4140 PF13600.1 EPE33144.1 - 1.4 9.3 7.1 0.97 9.9 0.2 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Nsp1_C PF05064.8 EPE33144.1 - 1.5 8.4 7.1 0.43 10.2 0.4 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region IncA PF04156.9 EPE33144.1 - 3.3 7.2 10.9 1.1 8.7 0.5 2.0 2 0 0 2 2 2 0 IncA protein TBCA PF02970.11 EPE33144.1 - 3.4 7.8 10.7 5.6 7.1 5.9 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor A p450 PF00067.17 EPE33145.1 - 1.4e-68 231.4 0.0 1.8e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CVNH PF08881.5 EPE33146.1 - 2.9e-07 30.6 0.0 5.3e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 CVNH domain AA_permease_2 PF13520.1 EPE33147.1 - 6.7e-60 202.8 50.3 8.1e-60 202.5 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE33147.1 - 5.8e-11 41.4 41.0 9.1e-11 40.7 28.4 1.3 1 0 0 1 1 1 1 Amino acid permease Metallophos PF00149.23 EPE33148.1 - 3.8e-09 36.2 3.2 1.6e-08 34.1 2.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPE33148.1 - 0.0021 17.9 0.0 0.0084 15.9 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2098 PF09871.4 EPE33148.1 - 0.09 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) APC10 PF03256.11 EPE33149.1 - 3.7e-49 166.9 0.0 5.3e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Daxx PF03344.10 EPE33149.1 - 0.71 8.2 7.7 0.94 7.8 5.3 1.1 1 0 0 1 1 1 0 Daxx Family RNA_pol_3_Rpc31 PF11705.3 EPE33149.1 - 0.75 9.6 9.5 1.1 9.1 6.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 COPI_C PF06957.6 EPE33149.1 - 5.4 5.4 10.0 7.7 4.9 7.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF2457 PF10446.4 EPE33149.1 - 9.6 4.8 14.4 15 4.1 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Gly_acyl_tr_C PF08444.5 EPE33150.1 - 0.00082 19.3 0.1 0.001 19.0 0.1 1.2 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF1127 PF06568.6 EPE33150.1 - 0.018 14.4 3.5 0.034 13.5 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) SecA_DEAD PF07517.9 EPE33150.1 - 0.1 11.8 0.5 0.11 11.7 0.3 1.0 1 0 0 1 1 1 0 SecA DEAD-like domain DUF479 PF04336.7 EPE33150.1 - 0.15 12.1 0.8 0.55 10.3 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF479 AATF-Che1 PF13339.1 EPE33150.1 - 0.23 11.6 2.7 0.11 12.7 0.3 1.6 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor HRXXH PF13933.1 EPE33152.1 - 0.0005 19.5 5.1 0.23 10.8 0.1 2.2 2 0 0 2 2 2 2 Putative peptidase family Peptidase_M35 PF02102.10 EPE33152.1 - 0.0021 16.8 0.9 0.003 16.2 0.6 1.3 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Vps51 PF08700.6 EPE33154.1 - 0.28 11.0 1.8 0.57 10.0 0.6 2.1 1 1 0 1 1 1 0 Vps51/Vps67 FAD_binding_4 PF01565.18 EPE33156.1 - 1.7e-20 72.9 1.6 3.9e-20 71.7 1.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE33156.1 - 5.5e-12 45.4 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like zf-CCCH PF00642.19 EPE33157.1 - 0.046 13.4 1.1 0.046 13.4 0.7 3.0 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Toxin_21 PF08091.6 EPE33157.1 - 1.6 8.4 7.7 0.74 9.5 1.1 2.5 2 0 0 2 2 2 0 Spider insecticidal peptide SET PF00856.23 EPE33158.1 - 3.6e-10 40.3 0.4 4.9e-09 36.6 0.3 2.2 1 1 0 1 1 1 1 SET domain CARD PF00619.16 EPE33158.1 - 0.094 12.5 1.2 0.25 11.1 0.8 1.8 1 0 0 1 1 1 0 Caspase recruitment domain Asp_protease_2 PF13650.1 EPE33160.1 - 0.11 13.0 0.0 0.35 11.3 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease DUF2723 PF11028.3 EPE33161.1 - 0.0072 15.8 3.1 0.011 15.1 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) Ala_racemase_N PF01168.15 EPE33164.1 - 7.7e-42 143.3 0.0 9.3e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain MS_channel PF00924.13 EPE33165.1 - 2e-16 59.9 1.9 4.8e-16 58.7 1.3 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EPE33165.1 - 0.0045 16.1 0.1 0.0097 15.1 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EPE33165.1 - 0.0091 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EPE33165.1 - 0.065 13.3 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF605 PF04652.11 EPE33165.1 - 0.51 9.6 13.7 0.81 9.0 9.5 1.2 1 0 0 1 1 1 0 Vta1 like AAA_16 PF13191.1 EPE33166.1 - 0.31 10.9 2.5 0.35 10.8 1.7 1.0 1 0 0 1 1 1 0 AAA ATPase domain Zip PF02535.17 EPE33167.1 - 2.6e-36 125.2 16.8 2.6e-36 125.2 11.7 2.1 2 0 0 2 2 2 1 ZIP Zinc transporter HRXXH PF13933.1 EPE33168.1 - 3.1e-96 321.5 0.0 3.1e-96 321.5 0.0 1.5 2 0 0 2 2 2 1 Putative peptidase family SSP160 PF06933.6 EPE33168.1 - 5 4.9 16.8 7.4 4.4 11.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 LSM PF01423.17 EPE33169.1 - 2.9e-12 45.9 0.0 3.7e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain ECH_C PF13766.1 EPE33170.1 - 8e-33 113.0 0.3 1.9e-32 111.8 0.2 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EPE33170.1 - 5.2e-24 84.7 0.0 6.3e-23 81.1 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family GATA PF00320.22 EPE33172.1 - 1.1e-06 27.9 3.8 0.0038 16.5 0.5 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF2543 PF10820.3 EPE33172.1 - 0.085 12.8 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) Rep_fac-A_3 PF08661.6 EPE33173.1 - 8.4e-25 86.7 0.0 9.7e-25 86.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ribosomal_L4 PF00573.17 EPE33174.1 - 1e-43 148.9 0.0 1.4e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family RNA_pol_Rpb2_6 PF00562.23 EPE33174.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 PBP PF01161.15 EPE33175.1 - 9.2e-13 48.2 0.0 1.5e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PH PF00169.24 EPE33176.1 - 6.6e-25 87.3 1.1 7e-13 48.6 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EPE33176.1 - 5.8e-10 39.4 2.9 1.4e-05 25.2 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EPE33176.1 - 2.5e-08 34.0 0.6 0.0025 17.9 0.1 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EPE33176.1 - 2.4e-05 24.2 0.1 4.8e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EPE33176.1 - 3.8e-05 23.5 0.2 7.8e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 PH domain GTP_EFTU PF00009.22 EPE33177.1 - 2e-53 180.6 0.0 3.6e-53 179.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EPE33177.1 - 3.2e-16 58.9 0.0 1.1e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPE33177.1 - 9.9e-09 35.2 0.0 2.8e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EPE33177.1 - 5.4e-07 29.3 0.0 1.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EPE33177.1 - 3.8e-05 23.2 0.0 0.0012 18.3 0.0 3.0 2 1 1 3 3 3 1 Elongation factor G, domain IV SET PF00856.23 EPE33177.1 - 0.0056 17.0 0.4 0.024 14.9 0.1 2.1 2 0 0 2 2 2 1 SET domain MMR_HSR1 PF01926.18 EPE33177.1 - 0.0097 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase D123 PF07065.9 EPE33177.1 - 0.023 13.7 0.1 0.043 12.9 0.1 1.3 1 0 0 1 1 1 0 D123 DUF768 PF05589.6 EPE33178.1 - 0.015 15.2 0.2 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF768) Syntaxin_2 PF14523.1 EPE33178.1 - 0.054 13.5 0.1 0.74 9.8 0.0 2.6 2 0 0 2 2 2 0 Syntaxin-like protein C6_DPF PF10170.4 EPE33181.1 - 0.18 11.8 3.5 0.35 10.9 2.5 1.5 1 1 1 2 2 2 0 Cysteine-rich domain Cupin_1 PF00190.17 EPE33184.1 - 1e-24 86.6 0.0 3e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EPE33184.1 - 1e-23 82.6 0.1 2.4e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EPE33184.1 - 3.9e-09 35.7 0.0 0.0003 20.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 EPE33184.1 - 1.3e-05 24.9 0.0 0.00042 19.9 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.14 EPE33184.1 - 0.00011 21.8 0.1 0.0043 16.7 0.0 2.5 3 0 0 3 3 3 1 AraC-like ligand binding domain 3-HAO PF06052.7 EPE33184.1 - 0.00076 18.9 0.0 0.0025 17.2 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.2 EPE33184.1 - 0.019 14.6 0.0 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 Cupin CENP-C_C PF11699.3 EPE33184.1 - 0.18 11.8 0.0 0.64 10.0 0.0 1.8 2 0 0 2 2 2 0 Mif2/CENP-C like Tom22 PF04281.8 EPE33185.1 - 7.7e-44 148.5 0.8 1.4e-43 147.6 0.6 1.5 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Bestrophin PF01062.16 EPE33185.1 - 2e-35 122.1 0.7 2.1e-21 76.1 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Pol_alpha_B_N PF08418.5 EPE33186.1 - 4.1e-59 200.1 1.1 5.2e-59 199.8 0.8 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EPE33186.1 - 3.2e-38 131.0 0.0 4.4e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Prp19_bind PF06991.6 EPE33187.1 - 2.3e-47 161.6 32.4 2.3e-47 161.6 22.4 2.0 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain DUF4619 PF15398.1 EPE33187.1 - 0.83 9.0 16.7 0.69 9.2 2.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4619) Alb1 PF09135.6 EPE33188.1 - 8.3e-23 81.1 12.9 8.3e-23 81.1 9.0 1.6 2 0 0 2 2 2 1 Alb1 UCH PF00443.24 EPE33189.1 - 1.4e-38 132.5 0.0 1.8e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPE33189.1 - 1.4e-08 34.5 0.0 2.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase COMPASS-Shg1 PF05205.7 EPE33190.1 - 6e-23 81.1 0.3 6e-23 81.1 0.2 2.2 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF-2B PF01008.12 EPE33192.1 - 1.6e-75 253.7 0.0 2e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family FleQ PF06490.6 EPE33192.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Glyco_transf_28 PF03033.15 EPE33196.1 - 8.3e-22 77.4 0.0 2.3e-21 75.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EPE33196.1 - 2.4e-05 23.0 0.0 3.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EPE33196.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PGAP1 PF07819.8 EPE33197.1 - 6e-05 22.7 0.0 9.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPE33197.1 - 0.0026 17.5 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE33197.1 - 0.0048 16.8 0.2 0.012 15.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EPE33197.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.15 EPE33197.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2305 PF10230.4 EPE33197.1 - 0.068 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EPE33197.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 EPE33197.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Fungal_trans_2 PF11951.3 EPE33198.1 - 9.6e-08 31.0 0.2 1.4e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE33198.1 - 0.011 15.6 1.4 0.023 14.5 0.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3 PF00933.16 EPE33200.1 - 1.6e-92 309.7 0.0 2.2e-92 309.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE33200.1 - 8.7e-52 175.8 0.0 7.9e-51 172.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE33200.1 - 9.6e-18 63.8 0.1 1.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Carb_anhydrase PF00194.16 EPE33201.1 - 8.4e-22 77.3 0.0 2.4e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF4211 PF13926.1 EPE33202.1 - 2e-33 114.9 0.0 2e-33 114.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) BTB PF00651.26 EPE33203.1 - 1.2e-07 31.6 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.17 EPE33205.1 - 5.1e-07 29.8 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain COesterase PF00135.23 EPE33206.1 - 1e-94 318.1 1.2 5.7e-87 292.6 0.7 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE33206.1 - 1.5e-11 44.3 0.0 2.6e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2125 PF09898.4 EPE33207.1 - 0.027 13.7 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) NDT80_PhoG PF05224.7 EPE33208.1 - 0.039 13.9 0.6 0.05 13.5 0.4 1.1 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family Sugar_tr PF00083.19 EPE33209.1 - 1.3e-78 264.6 30.4 1.5e-78 264.3 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE33209.1 - 8e-18 64.2 42.1 2.8e-11 42.7 11.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE33209.1 - 1.1e-06 27.3 35.2 6.6e-06 24.7 2.3 3.7 3 2 1 4 4 4 3 MFS/sugar transport protein zf-MYND PF01753.13 EPE33210.1 - 3.5e-10 39.5 13.4 5.9e-10 38.8 9.3 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EPE33210.1 - 0.003 17.3 10.5 0.0062 16.3 7.3 1.5 1 1 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 C1_1 PF00130.17 EPE33210.1 - 0.41 10.4 8.4 8.4 6.2 5.8 2.2 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-TFIIB PF13453.1 EPE33210.1 - 0.59 9.3 4.6 1.4 8.1 3.2 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger Ecl1 PF12855.2 EPE33210.1 - 1.1 8.6 8.3 2.7 7.3 5.7 1.7 1 1 0 1 1 1 0 Life-span regulatory factor zf-HIT PF04438.11 EPE33210.1 - 5.8 6.6 12.0 1.5 8.5 4.5 2.3 2 0 0 2 2 2 0 HIT zinc finger Dak1 PF02733.12 EPE33212.1 - 2.7e-111 371.2 7.6 3.9e-111 370.7 5.3 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EPE33212.1 - 3.8e-45 153.6 1.4 8.7e-45 152.5 1.0 1.6 1 0 0 1 1 1 1 DAK2 domain EXOSC1 PF10447.4 EPE33213.1 - 1.8e-28 98.2 0.6 2.7e-28 97.7 0.4 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EPE33213.1 - 5.4e-15 54.3 0.0 1.1e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region FeoC PF09012.5 EPE33214.1 - 0.12 12.1 0.5 0.2 11.3 0.1 1.6 2 0 0 2 2 2 0 FeoC like transcriptional regulator OEP PF02321.13 EPE33214.1 - 0.58 9.7 4.4 0.69 9.4 3.0 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein RhoGAP PF00620.22 EPE33216.1 - 1.7e-12 47.1 0.0 4.8e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain WEMBL PF05701.6 EPE33216.1 - 0.0086 14.5 1.1 0.017 13.6 0.7 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Bap31 PF05529.7 EPE33216.1 - 1.4 8.3 3.6 6.6 6.1 2.4 2.0 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like CBS PF00571.23 EPE33217.1 - 2.8e-29 100.6 7.8 5.4e-14 51.6 0.1 4.3 4 0 0 4 4 4 4 CBS domain Erp_C PF06780.6 EPE33217.1 - 0.046 13.5 0.2 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Erp protein C-terminus Arm PF00514.18 EPE33219.1 - 6.5e-67 219.2 33.7 3.4e-13 48.8 0.1 11.2 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPE33219.1 - 8.6e-23 80.4 16.3 3.2e-05 24.1 1.2 7.5 1 1 4 6 6 6 5 HEAT repeats HEAT PF02985.17 EPE33219.1 - 2.2e-19 67.7 16.2 0.022 14.7 0.1 9.4 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 EPE33219.1 - 4.1e-16 58.9 15.8 0.0022 18.4 0.1 8.1 6 2 3 9 9 9 6 HEAT-like repeat Adaptin_N PF01602.15 EPE33219.1 - 7.8e-13 47.5 8.4 2.4e-08 32.7 0.2 2.8 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 EPE33219.1 - 5.9e-11 41.9 8.9 0.0048 16.0 1.8 3.5 2 1 1 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 EPE33219.1 - 1.2e-09 37.7 3.1 0.001 18.3 0.1 3.8 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 EPE33219.1 - 1.9e-09 36.0 0.6 4e-09 34.9 0.2 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) HEAT_PBS PF03130.11 EPE33219.1 - 0.0017 18.6 8.7 4.5 8.0 0.8 6.7 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPE33219.1 - 0.0034 17.7 0.6 0.49 10.8 0.1 3.9 3 1 2 5 5 5 1 Vacuolar 14 Fab1-binding region DUF908 PF06012.7 EPE33219.1 - 0.0039 16.5 2.5 1.2 8.4 0.2 3.7 2 1 2 4 4 4 1 Domain of Unknown Function (DUF908) DUF2454 PF10521.4 EPE33219.1 - 0.0073 15.3 0.5 0.027 13.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) RIX1 PF08167.7 EPE33219.1 - 0.014 15.1 0.7 0.22 11.1 0.2 2.8 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Vpu PF00558.14 EPE33219.1 - 0.014 14.8 0.9 0.044 13.3 0.2 2.1 2 0 0 2 2 2 0 Vpu protein V-ATPase_H_C PF11698.3 EPE33219.1 - 0.016 15.0 4.8 13 5.7 0.0 4.6 2 1 5 7 7 7 0 V-ATPase subunit H Peptidase_S24 PF00717.18 EPE33220.1 - 3e-09 36.4 0.2 4.9e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EPE33220.1 - 2.3e-05 23.9 0.0 0.0017 17.8 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 IF3_C PF00707.17 EPE33221.1 - 5.4e-08 32.4 1.1 1.3e-07 31.2 0.8 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 EPE33221.1 - 0.0084 16.0 2.0 0.056 13.3 1.4 2.3 1 1 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain ORC3_N PF07034.6 EPE33221.1 - 0.036 13.0 3.2 0.42 9.5 0.0 2.1 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus DUF830 PF05708.7 EPE33221.1 - 0.11 12.5 0.5 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) Kinesin-relat_1 PF12711.2 EPE33222.1 - 0.16 12.3 6.7 0.62 10.5 4.6 2.0 1 0 0 1 1 1 0 Kinesin motor TMCO5 PF14992.1 EPE33222.1 - 2.9 6.9 10.4 0.054 12.6 2.1 1.8 2 0 0 2 2 2 0 TMCO5 family ADIP PF11559.3 EPE33222.1 - 3.2 7.6 20.7 0.17 11.7 6.6 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2216 PF10226.4 EPE33222.1 - 3.5 7.0 11.3 0.19 11.1 0.8 2.6 1 1 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) HSP70 PF00012.15 EPE33223.1 - 2e-11 42.5 1.6 3.7e-09 35.0 0.2 2.7 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EPE33223.1 - 0.00031 19.4 0.1 0.005 15.4 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein WSC PF01822.14 EPE33224.1 - 2e-55 184.6 63.2 1.2e-19 70.0 8.5 4.7 4 1 1 5 5 5 3 WSC domain DUF3494 PF11999.3 EPE33224.1 - 1.4e-39 135.9 17.3 1.4e-39 135.9 12.0 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3494) HeLo PF14479.1 EPE33225.1 - 9.8e-06 25.4 2.3 0.0076 16.0 0.2 2.6 1 1 1 2 2 2 2 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 EPE33225.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Malic_M PF03949.10 EPE33226.1 - 1.2e-86 290.4 0.0 1.6e-86 290.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EPE33226.1 - 7.5e-69 230.9 0.0 1.3e-68 230.1 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain AlaDh_PNT_C PF01262.16 EPE33226.1 - 0.12 11.9 0.1 0.25 10.8 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain His_Phos_1 PF00300.17 EPE33227.1 - 5.2e-17 62.3 0.0 6.7e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NUDIX PF00293.23 EPE33228.1 - 7.8e-10 38.5 0.0 1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain zf-C2H2_4 PF13894.1 EPE33229.1 - 0.00014 21.9 31.0 0.019 15.2 1.6 5.0 4 1 1 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE33229.1 - 0.0047 17.2 35.6 0.12 12.7 1.3 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.2 EPE33229.1 - 0.95 9.7 13.2 0.95 9.7 0.6 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Myb_DNA-bind_6 PF13921.1 EPE33230.1 - 1e-09 38.3 1.1 3.9e-09 36.4 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPE33230.1 - 3.7e-07 30.1 0.1 8.6e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Patatin PF01734.17 EPE33230.1 - 7.4e-06 26.0 0.0 2.7e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Patatin-like phospholipase ketoacyl-synt PF00109.21 EPE33230.1 - 3.9e-05 23.2 0.0 8.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain zf-C2H2_4 PF13894.1 EPE33230.1 - 6.1e-05 23.0 23.7 0.28 11.6 0.5 6.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPE33230.1 - 0.001 19.1 10.5 8.1 6.7 1.7 5.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding gag-asp_proteas PF13975.1 EPE33230.1 - 0.02 14.7 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EPE33230.1 - 0.038 14.5 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease zf-met PF12874.2 EPE33230.1 - 0.16 12.2 5.4 9.1 6.6 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EPE33230.1 - 2.8 8.4 31.4 0.47 10.9 0.7 6.8 6 0 0 6 6 6 0 Zinc finger, C2H2 type GFO_IDH_MocA PF01408.17 EPE33234.1 - 2.5e-20 73.1 0.1 4.3e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPE33234.1 - 3.2e-05 23.6 0.0 7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EPE33234.1 - 0.1 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF3425 PF11905.3 EPE33235.1 - 2.8e-31 108.2 0.3 4.5e-31 107.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF1814 PF08843.6 EPE33237.1 - 2.9e-06 27.2 0.3 1.1e-05 25.3 0.2 1.8 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) CcmD PF04995.9 EPE33238.1 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) DUF4190 PF13828.1 EPE33238.1 - 0.038 13.5 0.0 0.049 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) DUF4129 PF13559.1 EPE33238.1 - 0.9 9.5 3.6 3.2 7.7 2.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) Aldo_ket_red PF00248.16 EPE33239.1 - 3.9e-44 150.5 0.0 5e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ApoLp-III PF07464.6 EPE33241.1 - 0.033 14.2 1.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Latarcin PF10279.4 EPE33241.1 - 0.041 14.0 0.3 0.08 13.1 0.2 1.5 1 0 0 1 1 1 0 Latarcin precursor DUF2973 PF11189.3 EPE33242.1 - 0.14 11.9 0.1 0.18 11.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2973) DUF1180 PF06679.7 EPE33242.1 - 6 6.7 7.3 54 3.6 5.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) ADH_N PF08240.7 EPE33243.1 - 6.3e-10 38.7 0.1 2.1e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPE33243.1 - 2.9e-06 28.1 0.0 7.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UPF0047 PF01894.12 EPE33244.1 - 7.2e-41 138.7 0.0 8.2e-41 138.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 NUDIX_2 PF13869.1 EPE33245.1 - 2.7e-82 274.6 0.0 3.2e-82 274.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase NACHT PF05729.7 EPE33246.1 - 1.3e-12 47.6 0.0 3.5e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EPE33246.1 - 0.008 16.3 0.0 0.038 14.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPE33246.1 - 0.011 15.9 0.6 0.11 12.8 0.0 2.3 1 1 1 2 2 2 0 ABC transporter T2SF PF00482.18 EPE33246.1 - 0.021 14.7 0.1 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F AAA_30 PF13604.1 EPE33246.1 - 0.16 11.5 0.0 0.39 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain Cutinase PF01083.17 EPE33248.1 - 1.7e-51 174.5 5.0 1.9e-51 174.3 3.5 1.0 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 EPE33248.1 - 0.00011 21.7 0.2 0.00015 21.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EPE33248.1 - 0.0012 18.5 0.1 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EPE33248.1 - 0.012 15.3 0.6 0.016 14.9 0.4 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIP PF03583.9 EPE33248.1 - 0.035 13.3 0.6 0.049 12.8 0.4 1.2 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_9 PF10081.4 EPE33248.1 - 0.066 11.9 0.0 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Abhydrolase_3 PF07859.8 EPE33248.1 - 0.069 12.7 0.4 0.083 12.4 0.3 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 EPE33248.1 - 0.087 12.1 0.2 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3425 PF11905.3 EPE33249.1 - 6.7e-34 116.6 0.1 1.5e-33 115.5 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EPE33249.1 - 0.13 12.2 11.2 0.25 11.3 7.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor Peptidase_C2 PF00648.16 EPE33250.1 - 1.7e-49 168.4 0.3 1.4e-33 116.2 0.1 2.5 2 0 0 2 2 2 2 Calpain family cysteine protease CoaE PF01121.15 EPE33252.1 - 3.4e-42 143.8 0.0 9.3e-42 142.4 0.0 1.6 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 EPE33252.1 - 0.0026 17.6 0.0 0.017 15.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE33252.1 - 0.027 15.2 0.7 0.11 13.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EPE33252.1 - 0.15 12.3 0.5 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain COesterase PF00135.23 EPE33253.1 - 5.1e-109 365.3 0.4 1e-108 364.3 0.3 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE33253.1 - 0.00012 21.6 1.2 0.00076 19.1 0.8 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE33253.1 - 0.0073 16.0 0.6 0.017 14.8 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Tim17 PF02466.14 EPE33255.1 - 3.5e-50 169.3 7.1 6e-50 168.5 4.9 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.1 EPE33255.1 - 0.013 15.0 0.9 0.013 15.0 0.6 2.6 2 0 0 2 2 2 0 Glycine zipper DLH PF01738.13 EPE33255.1 - 0.065 12.5 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF3602 PF12223.3 EPE33255.1 - 1.3 9.4 3.5 17 5.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3602) Glyco_hydro_16 PF00722.16 EPE33256.1 - 5.7e-08 32.2 0.2 1.7e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GP41 PF00517.12 EPE33256.1 - 0.057 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral envelope protein EphA2_TM PF14575.1 EPE33256.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain KR PF08659.5 EPE33257.1 - 4.6e-57 192.6 0.0 1.3e-56 191.1 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EPE33257.1 - 1e-55 188.9 0.0 1.5e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EPE33257.1 - 1e-44 152.3 0.1 3.6e-43 147.3 0.0 3.0 3 0 0 3 3 3 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 EPE33257.1 - 4.2e-32 111.7 0.0 7.1e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.7 EPE33257.1 - 3.3e-17 62.7 0.0 1.4e-16 60.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EPE33257.1 - 5.3e-17 61.5 0.0 1.8e-16 59.8 0.0 2.0 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE33257.1 - 2e-12 48.1 0.0 7.4e-12 46.2 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EPE33257.1 - 9.2e-12 44.9 0.0 2.8e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE33257.1 - 7.4e-10 38.6 0.0 2.5e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE33257.1 - 2.7e-09 37.5 0.1 1.9e-06 28.4 0.0 3.8 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE33257.1 - 1.7e-06 28.4 0.0 1.5e-05 25.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EPE33257.1 - 8.4e-06 25.9 0.1 2.7e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EPE33257.1 - 1e-05 25.2 0.2 2e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 EPE33257.1 - 0.00022 21.5 0.0 0.065 13.6 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE33257.1 - 0.00031 19.9 0.0 0.0007 18.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family T2SM_b PF10741.4 EPE33257.1 - 0.0023 17.5 0.0 0.0058 16.2 0.0 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M subtype b NodS PF05401.6 EPE33257.1 - 0.0087 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 EPE33257.1 - 0.012 15.0 0.0 0.094 12.1 0.0 2.4 2 1 0 2 2 2 0 Putative methyltransferase 3Beta_HSD PF01073.14 EPE33257.1 - 0.031 12.9 0.0 0.06 12.0 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ketoacyl-synt PF00109.21 EPE33258.1 - 5.1e-70 235.8 0.0 7.4e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EPE33258.1 - 8e-34 116.0 0.2 1.3e-33 115.3 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EPE33258.1 - 3.6e-07 29.8 0.2 5.4e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Acyl transferase domain Thiolase_N PF00108.18 EPE33258.1 - 4.5e-06 25.8 0.2 7.3e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EPE33258.1 - 0.0027 17.3 0.2 0.0054 16.3 0.2 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TRAM_LAG1_CLN8 PF03798.11 EPE33259.1 - 5.8e-18 65.1 4.3 7e-18 64.8 3.0 1.1 1 0 0 1 1 1 1 TLC domain MFS_1 PF07690.11 EPE33260.1 - 1.5e-36 125.8 51.1 9.5e-36 123.2 32.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPE33260.1 - 8.4e-18 63.8 20.3 1.8e-17 62.8 14.1 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE33260.1 - 1.3e-14 53.6 20.0 1.3e-14 53.6 13.9 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EPE33260.1 - 0.014 13.4 6.2 0.019 13.0 0.7 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ETRAMP PF09716.5 EPE33260.1 - 6.1 6.8 6.9 33 4.5 0.0 3.6 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF3291 PF11695.3 EPE33262.1 - 0.015 14.7 0.1 0.042 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) BRF1 PF07741.8 EPE33262.1 - 0.026 14.7 0.8 0.026 14.7 0.5 2.9 3 0 0 3 3 3 0 Brf1-like TBP-binding domain DBINO PF13892.1 EPE33263.1 - 0.00042 20.3 5.2 0.00048 20.1 3.6 1.1 1 0 0 1 1 1 1 DNA-binding domain DUF4398 PF14346.1 EPE33263.1 - 0.22 11.6 9.7 0.34 11.0 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) CAF-1_p150 PF11600.3 EPE33263.1 - 0.29 10.4 12.1 0.49 9.7 8.4 1.3 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BHD_2 PF10404.4 EPE33263.1 - 3 8.2 5.0 4.8 7.5 3.2 1.5 1 1 0 1 1 1 0 Rad4 beta-hairpin domain 2 Reo_sigmaC PF04582.7 EPE33264.1 - 5.6e-05 22.4 16.8 0.024 13.8 7.0 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein ATG16 PF08614.6 EPE33264.1 - 0.0002 21.2 14.9 0.00027 20.8 9.7 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Bacillus_HBL PF05791.6 EPE33264.1 - 0.00028 20.2 1.1 0.00058 19.2 0.6 1.7 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) TSC22 PF01166.13 EPE33264.1 - 0.00032 20.6 7.3 0.12 12.3 0.3 4.2 2 1 2 4 4 4 1 TSC-22/dip/bun family TMF_DNA_bd PF12329.3 EPE33264.1 - 0.0004 20.1 18.2 0.021 14.6 2.2 3.0 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 EPE33264.1 - 0.0011 18.7 8.0 0.0011 18.7 5.5 2.8 2 1 1 3 3 2 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 EPE33264.1 - 0.0018 17.8 16.4 0.045 13.3 0.7 2.2 1 1 1 2 2 2 2 IncA protein Rab5-bind PF09311.6 EPE33264.1 - 0.0034 17.3 7.2 0.15 11.9 1.7 3.1 1 1 2 3 3 3 1 Rabaptin-like protein ADIP PF11559.3 EPE33264.1 - 0.0056 16.5 9.6 0.01 15.7 1.8 2.6 2 1 1 3 3 2 1 Afadin- and alpha -actinin-Binding GAS PF13851.1 EPE33264.1 - 0.0071 15.5 6.0 0.74 8.9 1.7 2.9 1 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EPE33264.1 - 0.0081 14.8 11.4 0.021 13.4 5.0 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein EzrA PF06160.7 EPE33264.1 - 0.011 14.0 6.4 0.0081 14.3 2.5 2.0 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF972 PF06156.8 EPE33264.1 - 0.012 15.9 6.8 0.48 10.7 0.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Kinesin-relat_1 PF12711.2 EPE33264.1 - 0.013 15.9 7.3 0.25 11.7 0.5 3.4 2 1 1 3 3 2 0 Kinesin motor AAA_13 PF13166.1 EPE33264.1 - 0.025 13.0 8.9 0.042 12.3 6.0 1.4 1 1 1 2 2 2 0 AAA domain DUF4201 PF13870.1 EPE33264.1 - 0.032 13.6 4.2 0.095 12.1 2.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF1640 PF07798.6 EPE33264.1 - 0.033 14.2 6.5 0.037 14.0 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) TPD52 PF04201.10 EPE33264.1 - 0.04 13.6 11.3 0.28 10.8 1.5 3.7 1 1 3 4 4 4 0 Tumour protein D52 family DUF3450 PF11932.3 EPE33264.1 - 0.058 12.6 5.0 0.41 9.8 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) RBD-FIP PF09457.5 EPE33264.1 - 0.098 12.4 0.4 0.3 10.9 0.2 1.9 1 0 0 1 1 1 0 FIP domain Lebercilin PF15619.1 EPE33264.1 - 0.15 11.4 8.1 0.69 9.3 5.6 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Tup_N PF08581.5 EPE33264.1 - 0.16 12.1 1.3 0.94 9.7 0.4 2.8 1 1 1 2 2 1 0 Tup N-terminal TMF_TATA_bd PF12325.3 EPE33264.1 - 0.16 11.6 13.6 1.8 8.3 0.5 3.3 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding TBPIP PF07106.8 EPE33264.1 - 0.18 11.3 7.3 0.39 10.2 2.8 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4200 PF13863.1 EPE33264.1 - 0.2 11.5 4.8 0.57 10.1 3.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Atg14 PF10186.4 EPE33264.1 - 0.27 10.1 11.2 0.9 8.4 6.8 2.1 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 EPE33264.1 - 0.39 10.3 4.3 1.6 8.3 2.9 2.0 1 1 1 2 2 2 0 Mnd1 family Fib_alpha PF08702.5 EPE33264.1 - 0.42 10.7 2.4 2 8.5 1.3 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1515 PF07439.6 EPE33264.1 - 0.42 10.4 2.4 6.7 6.5 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) SlyX PF04102.7 EPE33264.1 - 0.46 10.9 2.1 8 6.9 0.3 2.8 2 0 0 2 2 2 0 SlyX CCDC155 PF14662.1 EPE33264.1 - 0.46 10.0 14.2 2.7 7.5 1.0 3.1 1 1 1 3 3 3 0 Coiled-coil region of CCDC155 CENP-Q PF13094.1 EPE33264.1 - 0.54 10.2 10.9 1.5 8.7 7.5 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Lzipper-MIP1 PF14389.1 EPE33264.1 - 0.6 10.2 6.6 0.95 9.6 2.8 2.6 2 1 1 3 3 2 0 Leucine-zipper of ternary complex factor MIP1 BLOC1_2 PF10046.4 EPE33264.1 - 0.74 9.9 6.8 0.82 9.8 1.1 2.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.10 EPE33264.1 - 0.78 9.7 14.0 0.86 9.5 6.7 2.6 1 1 1 2 2 2 0 Fez1 DUF724 PF05266.9 EPE33264.1 - 0.83 9.2 10.3 4 7.0 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF641 PF04859.7 EPE33264.1 - 0.87 9.3 7.3 0.69 9.6 1.1 2.6 1 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Shugoshin_N PF07558.6 EPE33264.1 - 0.91 9.2 5.2 0.73 9.5 0.9 3.0 2 1 0 2 2 1 0 Shugoshin N-terminal coiled-coil region Phage_GP20 PF06810.6 EPE33264.1 - 1 8.8 5.5 6.4 6.2 0.2 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 KLRAQ PF10205.4 EPE33264.1 - 1.2 9.2 7.8 0.63 10.0 0.5 2.6 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF904 PF06005.7 EPE33264.1 - 1.2 9.4 6.0 4.5 7.6 0.1 2.9 3 1 0 3 3 2 0 Protein of unknown function (DUF904) FUSC PF04632.7 EPE33264.1 - 1.3 7.3 6.9 1.6 7.0 4.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family COG2 PF06148.6 EPE33264.1 - 1.8 8.4 7.4 2.3 8.1 0.9 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.6 EPE33264.1 - 2.1 8.7 7.6 4.6 7.7 2.4 3.0 1 1 3 4 4 4 0 Syntaxin 6, N-terminal DivIC PF04977.10 EPE33264.1 - 2.5 7.6 10.5 3.9 7.0 0.7 3.3 1 1 1 3 3 3 0 Septum formation initiator CENP-F_leu_zip PF10473.4 EPE33264.1 - 2.6 7.8 14.7 8.4 6.2 0.9 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EPE33264.1 - 2.8 6.9 10.5 15 4.4 7.4 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 Bap31 PF05529.7 EPE33264.1 - 5.7 6.3 6.9 6.5 6.1 1.8 2.4 1 1 2 3 3 3 0 B-cell receptor-associated protein 31-like Cauli_VI PF01693.11 EPE33267.1 - 1.9e-17 62.9 2.9 2.8e-08 33.6 0.1 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin DUF2824 PF11039.3 EPE33267.1 - 0.03 14.0 0.1 0.041 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) HycH PF07450.6 EPE33267.1 - 0.036 14.1 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH GBP_C PF02841.9 EPE33268.1 - 0.083 12.0 3.4 0.11 11.6 2.3 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain SET PF00856.23 EPE33269.1 - 1.2e-06 28.9 0.0 2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 SET domain IFT20 PF14931.1 EPE33269.1 - 0.12 12.2 0.7 0.34 10.8 0.5 1.7 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DEAD PF00270.24 EPE33271.1 - 2.6e-32 111.6 0.2 2.1e-15 56.6 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE33271.1 - 3.2e-20 71.7 0.1 1.1e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE33271.1 - 1.3e-07 31.5 0.0 1.3e-07 31.5 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EPE33271.1 - 0.0049 15.8 0.0 0.0093 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PIGA PF08288.7 EPE33272.1 - 2.2e-46 156.1 3.2 3.4e-46 155.5 0.7 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EPE33272.1 - 1.4e-27 96.2 0.0 2.2e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EPE33272.1 - 1.5e-17 63.8 0.4 2.7e-17 63.0 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EPE33272.1 - 5e-17 62.3 0.1 9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EPE33272.1 - 3.1e-13 50.1 0.0 5.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EPE33272.1 - 1.1e-05 25.2 0.1 2e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EPE33272.1 - 0.00046 20.3 0.0 0.0014 18.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Tyrosinase PF00264.15 EPE33273.1 - 1.3e-43 149.7 0.3 1.7e-43 149.3 0.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase 2-Hacid_dh_C PF02826.14 EPE33274.1 - 9.1e-42 142.1 0.0 1.9e-27 95.5 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EPE33274.1 - 0.0031 17.3 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EPE33274.1 - 0.017 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EPE33274.1 - 0.029 14.3 0.0 0.18 11.8 0.0 2.3 1 1 1 2 2 2 0 TrkA-N domain 2-Hacid_dh PF00389.25 EPE33274.1 - 0.044 13.2 0.0 0.071 12.5 0.0 1.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EPE33274.1 - 0.06 13.1 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 EPE33274.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EPE33274.1 - 0.16 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain MFS_1 PF07690.11 EPE33275.1 - 7.1e-21 74.2 28.1 7.1e-21 74.2 19.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TPP1 PF10341.4 EPE33275.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD RseC_MucC PF04246.7 EPE33275.1 - 5.1 6.6 6.3 1.2 8.7 0.2 2.9 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Abhydrolase_6 PF12697.2 EPE33276.1 - 2.8e-22 79.7 0.5 3.5e-22 79.4 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE33276.1 - 3.3e-09 36.6 0.0 4.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE33276.1 - 3.9e-07 29.9 0.0 8.7e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE33276.1 - 0.029 14.2 0.1 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase Ser_hydrolase PF06821.8 EPE33276.1 - 0.049 13.2 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase TPP_enzyme_C PF02775.16 EPE33276.1 - 0.06 12.9 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF915 PF06028.6 EPE33276.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.9 EPE33276.1 - 0.13 10.7 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Pkinase PF00069.20 EPE33277.1 - 6.1e-24 84.5 0.0 1.3e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE33277.1 - 1.3e-12 47.3 0.0 9.3e-12 44.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPE33277.1 - 0.1 12.3 0.0 9.4 5.8 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family MYCBPAP PF14646.1 EPE33279.1 - 0.026 13.2 3.8 0.039 12.6 2.6 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family CorA PF01544.13 EPE33279.1 - 0.04 12.9 12.1 0.16 10.9 7.0 2.3 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 EPE33280.1 - 8.8e-19 67.6 0.0 1.5e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE33280.1 - 7e-08 31.8 0.0 3.3e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_28 PF00295.12 EPE33281.1 - 2.7e-32 112.0 5.8 3.6e-32 111.6 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EPE33281.1 - 3.1e-06 27.4 7.1 5e-06 26.8 4.3 1.9 1 1 0 1 1 1 1 Pectate lyase superfamily protein Fungal_trans_2 PF11951.3 EPE33282.1 - 8.6e-65 218.7 0.0 1.1e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE33282.1 - 2.2e-05 24.2 7.2 2.2e-05 24.2 5.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HrpA_pilin PF09589.5 EPE33282.1 - 0.057 13.8 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 HrpA pilus formation protein Acetyltransf_1 PF00583.19 EPE33284.1 - 4.8e-09 36.1 0.0 4.1e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EPE33284.1 - 5.3e-05 23.7 0.1 0.00048 20.6 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPE33284.1 - 8.8e-05 22.5 0.0 0.00035 20.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE33284.1 - 0.0032 17.3 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EPE33284.1 - 0.005 16.9 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HSP70 PF00012.15 EPE33285.1 - 6.8e-60 202.6 6.7 1.3e-56 191.7 0.0 2.8 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EPE33285.1 - 0.00094 17.8 0.1 0.0049 15.5 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EPE33285.1 - 0.058 13.0 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Ank_2 PF12796.2 EPE33286.1 - 5.9e-20 71.3 0.0 5.5e-06 26.6 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Pkinase PF00069.20 EPE33286.1 - 3.9e-19 68.8 0.0 6.8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE33286.1 - 1.1e-16 60.7 0.0 1.9e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.1 EPE33286.1 - 1.7e-11 43.1 0.3 2.2e-05 24.2 0.0 5.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 EPE33286.1 - 4.5e-09 35.6 4.5 0.00048 19.7 0.0 5.3 5 1 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EPE33286.1 - 3.3e-08 33.8 2.0 1.4e-05 25.4 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE33286.1 - 1e-06 28.8 0.7 0.0043 17.2 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Kdo PF06293.9 EPE33286.1 - 0.025 13.6 0.1 0.049 12.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPE33286.1 - 0.34 10.2 0.1 1.2 8.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family HeLo PF14479.1 EPE33287.1 - 1.6e-16 60.7 0.0 3e-16 59.8 0.0 1.5 1 1 0 1 1 1 1 Prion-inhibition and propagation CAF-1_p150 PF11600.3 EPE33288.1 - 0.00039 19.8 13.9 0.00039 19.8 9.6 2.2 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4449 PF14613.1 EPE33289.1 - 1.9e-64 216.4 2.8 1.9e-64 216.4 2.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) WHG PF13305.1 EPE33289.1 - 0.16 12.5 0.0 15 6.2 0.0 3.1 2 0 0 2 2 2 0 WHG domain DUF3452 PF11934.3 EPE33289.1 - 1 8.6 4.7 1.8 7.8 1.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3452) TBPIP PF07106.8 EPE33290.1 - 4.3 6.8 7.8 8.9 5.8 5.4 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ank_2 PF12796.2 EPE33291.1 - 2e-96 316.4 33.5 6.5e-16 58.4 0.4 10.3 4 2 7 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 EPE33291.1 - 9.5e-55 179.8 38.8 2.7e-05 23.7 0.0 17.6 19 0 0 19 19 19 13 Ankyrin repeat Ank_4 PF13637.1 EPE33291.1 - 7.6e-42 140.9 9.0 0.00016 22.1 0.0 13.0 10 3 3 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE33291.1 - 2.7e-38 126.1 23.9 0.0069 16.5 0.0 18.7 20 0 0 20 20 20 11 Ankyrin repeat Ank_5 PF13857.1 EPE33291.1 - 5.2e-29 99.6 25.2 0.021 15.0 0.0 15.7 12 5 6 18 18 18 9 Ankyrin repeats (many copies) Clr5 PF14420.1 EPE33291.1 - 1.1e-16 60.4 1.5 2.5e-16 59.2 1.0 1.7 1 0 0 1 1 1 1 Clr5 domain DNA_pol3_delt_C PF14840.1 EPE33292.1 - 0.072 13.1 0.1 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term Abhydrolase_4 PF08386.5 EPE33293.1 - 3.6e-20 71.7 0.1 1.1e-19 70.2 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 EPE33293.1 - 1.4e-14 54.2 0.1 8.9e-09 35.2 0.0 3.3 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE33293.1 - 2.5e-08 34.0 0.0 7.6e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE33293.1 - 0.00081 19.1 0.0 0.39 10.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family GTP_EFTU PF00009.22 EPE33295.1 - 2.8e-59 199.6 0.1 3.8e-59 199.3 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPE33295.1 - 1.3e-27 95.8 0.0 3.3e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPE33295.1 - 1.3e-17 63.7 5.1 2.2e-17 62.9 3.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPE33295.1 - 8.1e-06 25.7 0.0 2.1e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EPE33295.1 - 8.2e-05 22.1 0.8 0.00021 20.8 0.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EPE33295.1 - 0.0013 19.1 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EPE33295.1 - 0.042 13.3 0.2 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HET PF06985.6 EPE33296.1 - 6.3e-32 110.6 0.0 1.5e-31 109.4 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Muted PF14942.1 EPE33296.1 - 0.56 10.0 1.7 17 5.2 0.2 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Asp PF00026.18 EPE33297.1 - 1.2e-74 251.4 0.8 3.5e-66 223.6 1.7 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPE33297.1 - 0.00044 20.2 0.0 0.0027 17.6 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EPE33297.1 - 0.028 14.9 1.3 5 7.7 0.2 3.1 2 1 0 2 2 2 0 Aspartyl protease Rifin_STEVOR PF02009.11 EPE33297.1 - 0.15 11.6 0.6 0.25 10.9 0.4 1.2 1 0 0 1 1 1 0 Rifin/stevor family Herpes_gE PF02480.11 EPE33297.1 - 0.32 9.1 0.1 0.55 8.4 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ribosomal_S7 PF00177.16 EPE33298.1 - 9.6e-40 135.5 1.9 1.3e-39 135.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF1469 PF07332.6 EPE33299.1 - 8.9 6.0 11.2 17 5.1 2.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Mito_carr PF00153.22 EPE33300.1 - 2.7e-65 216.1 5.0 2.6e-22 78.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HET PF06985.6 EPE33301.1 - 1.2e-18 67.6 0.1 1.1e-10 41.8 0.1 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Laminin_II PF06009.7 EPE33302.1 - 0.19 11.4 4.5 0.66 9.7 3.1 1.9 1 0 0 1 1 1 0 Laminin Domain II CENP-X PF09415.5 EPE33303.1 - 6.9e-18 64.2 0.0 1.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Cu_bind_like PF02298.12 EPE33305.1 - 0.013 15.2 0.3 0.049 13.4 0.2 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Copper-bind PF00127.15 EPE33305.1 - 0.06 13.5 0.6 0.13 12.4 0.4 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Cyt-b5 PF00173.23 EPE33306.1 - 1.3e-10 40.8 0.1 2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S25 PF03297.10 EPE33307.1 - 2.8e-38 130.1 6.1 3.1e-38 130.0 4.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EPE33307.1 - 0.01 15.2 0.1 0.017 14.4 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.7 EPE33307.1 - 0.01 15.3 0.1 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain MarR_2 PF12802.2 EPE33307.1 - 0.016 14.8 0.1 0.031 13.9 0.1 1.5 1 1 1 2 2 2 0 MarR family Rrf2 PF02082.15 EPE33307.1 - 0.046 13.8 0.1 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator FeoC PF09012.5 EPE33307.1 - 0.047 13.3 0.2 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator PspB PF06667.7 EPE33308.1 - 0.028 14.3 0.1 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 Phage shock protein B DUF456 PF04306.8 EPE33308.1 - 0.053 13.5 0.5 0.053 13.5 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF456) Pmp3 PF01679.12 EPE33308.1 - 0.2 11.3 1.7 2.9 7.6 1.2 2.5 2 0 0 2 2 2 0 Proteolipid membrane potential modulator MFS_1 PF07690.11 EPE33309.1 - 7e-35 120.3 20.4 7e-35 120.3 14.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Adeno_E3_CR2 PF02439.10 EPE33309.1 - 0.14 11.7 0.9 0.99 8.9 0.0 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Glyco_hydro_76 PF03663.9 EPE33310.1 - 1.7e-140 468.6 6.5 2.2e-140 468.2 4.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EPE33310.1 - 0.0095 15.0 2.0 0.87 8.5 0.2 2.4 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 BTB_2 PF02214.17 EPE33311.1 - 2e-05 24.7 0.6 5.6e-05 23.2 0.4 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EPE33311.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain adh_short PF00106.20 EPE33312.1 - 7.2e-25 87.8 0.1 1.1e-24 87.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE33312.1 - 1.2e-11 44.8 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE33312.1 - 1.3e-08 34.6 0.0 2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPE33312.1 - 5.4e-06 26.5 0.1 0.00014 21.9 0.0 2.5 1 1 1 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 EPE33312.1 - 0.00028 20.1 0.0 0.00036 19.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 EPE33312.1 - 0.025 14.1 0.2 0.049 13.1 0.0 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase SSB PF00436.20 EPE33312.1 - 0.046 13.5 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Single-strand binding protein family YajC PF02699.10 EPE33312.1 - 0.15 11.7 0.1 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit DASH_Duo1 PF08651.5 EPE33312.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 Cache_2 PF08269.6 EPE33313.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Cache domain TRI12 PF06609.8 EPE33314.1 - 4.8e-39 134.0 23.3 5.7e-39 133.7 16.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EPE33314.1 - 1e-12 47.4 50.5 1.2e-12 47.2 31.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE33314.1 - 1.8e-07 30.1 8.8 1.8e-07 30.1 6.1 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.17 EPE33315.1 - 6.1e-69 232.7 0.0 8.8e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1446 PF07287.6 EPE33316.1 - 1.3e-120 402.1 0.6 1.6e-120 401.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Cyclase PF04199.8 EPE33317.1 - 1.2e-12 47.9 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase 2-Hacid_dh_C PF02826.14 EPE33318.1 - 2.3e-39 134.3 0.0 3.4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPE33318.1 - 9.5e-12 44.5 0.0 1.3e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPE33318.1 - 0.0023 17.7 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EPE33318.1 - 0.087 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PLU-1 PF08429.6 EPE33319.1 - 6.3e-104 347.4 17.6 2.6e-101 338.8 11.6 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EPE33319.1 - 4e-43 146.2 0.1 1.1e-42 144.8 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EPE33319.1 - 5.5e-28 96.6 0.1 1.7e-27 95.0 0.1 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EPE33319.1 - 1.3e-17 63.1 31.5 4e-09 36.0 5.3 3.6 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 EPE33319.1 - 2.2e-15 55.8 0.8 5.7e-15 54.5 0.6 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EPE33319.1 - 1.3e-14 53.9 5.9 3.4e-14 52.6 4.1 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.1 EPE33319.1 - 0.029 13.6 8.7 0.071 12.3 0.6 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain GIDA_assoc_3 PF13932.1 EPE33319.1 - 0.65 10.0 2.6 0.49 10.4 0.1 2.1 2 0 0 2 2 2 0 GidA associated domain 3 zf-RING_2 PF13639.1 EPE33319.1 - 2.3 8.1 21.9 5 7.0 4.0 2.6 2 0 0 2 2 2 0 Ring finger domain PHD_2 PF13831.1 EPE33319.1 - 5.6 6.3 12.7 0.29 10.5 1.3 2.9 2 0 0 2 2 2 0 PHD-finger GIY-YIG PF01541.19 EPE33320.1 - 5.6e-08 33.0 0.0 1.5e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.1 EPE33320.1 - 0.00033 20.6 0.7 0.00071 19.5 0.5 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EPE33320.1 - 0.00072 19.6 2.0 0.0017 18.4 1.4 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain FANCL_C PF11793.3 EPE33320.1 - 0.00086 19.2 3.6 0.0019 18.1 2.5 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.24 EPE33320.1 - 0.016 14.9 6.0 0.016 14.9 4.2 1.8 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.1 EPE33320.1 - 0.021 14.6 5.7 0.042 13.6 3.9 1.5 1 0 0 1 1 1 0 Ring finger domain Prok-RING_1 PF14446.1 EPE33320.1 - 0.34 10.6 3.5 0.95 9.2 0.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 EPE33320.1 - 1.5 8.6 4.8 0.67 9.7 1.6 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) COesterase PF00135.23 EPE33321.1 - 6.2e-103 345.3 0.0 8.4e-103 344.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE33321.1 - 3.2e-06 26.8 0.4 0.00046 19.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE33321.1 - 0.0083 15.3 0.5 0.015 14.5 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EPE33321.1 - 0.083 11.5 0.0 2.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) TPR_11 PF13414.1 EPE33322.1 - 5.3e-10 38.7 0.0 6.1e-07 28.9 0.0 3.3 3 0 0 3 3 3 2 TPR repeat UBA PF00627.26 EPE33322.1 - 4.3e-06 26.4 0.0 1.5e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.12 EPE33322.1 - 0.00023 20.8 0.0 1.8 8.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPE33322.1 - 0.0028 17.2 0.0 1.7 8.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF1688 PF07958.6 EPE33323.1 - 1.3e-176 587.2 0.0 1.5e-176 587.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) SNF2_N PF00176.18 EPE33324.1 - 3.2e-08 32.7 0.0 6e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF676 PF05057.9 EPE33326.1 - 2e-07 30.5 0.0 1.6e-06 27.5 0.0 2.2 2 1 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EPE33326.1 - 2.7e-05 23.8 0.0 4.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EPE33326.1 - 0.004 17.0 0.2 0.019 14.8 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 EPE33327.1 - 4.7e-08 33.4 0.0 7.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE33327.1 - 6.7e-07 29.0 0.0 8.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE33327.1 - 9.2e-05 22.8 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EPE33327.1 - 0.00023 20.8 0.0 0.00033 20.3 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.1 EPE33327.1 - 0.0011 18.7 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE33327.1 - 0.0013 19.0 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE33327.1 - 0.0014 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EPE33327.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DsrD PF08679.6 EPE33327.1 - 0.1 12.6 0.1 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) AA_permease_2 PF13520.1 EPE33329.1 - 1.3e-50 172.1 37.2 2.1e-50 171.5 25.8 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE33329.1 - 2.7e-08 32.5 36.2 3e-08 32.4 13.7 2.7 2 1 0 2 2 2 2 Amino acid permease Glyco_hyd_65N_2 PF14498.1 EPE33330.1 - 1.1e-56 192.2 1.3 1.6e-56 191.6 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Pyr_redox PF00070.22 EPE33331.1 - 2.2e-13 50.4 0.0 6.4e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE33331.1 - 1.4e-12 47.9 0.0 4.1e-12 46.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE33331.1 - 4.9e-05 23.4 0.0 0.027 14.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPE33331.1 - 5.6e-05 22.2 0.0 0.077 11.8 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EPE33331.1 - 0.00014 20.9 0.0 0.49 9.2 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 EPE33331.1 - 0.00021 20.3 0.1 0.079 11.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE33331.1 - 0.00044 20.2 0.0 0.064 13.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EPE33331.1 - 0.0027 17.7 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain Eno-Rase_NADH_b PF12242.3 EPE33331.1 - 0.0038 16.9 0.0 0.0099 15.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RuvA_N PF01330.16 EPE33331.1 - 0.0093 15.7 0.1 0.044 13.5 0.0 2.2 2 0 0 2 2 2 1 RuvA N terminal domain FAD_binding_3 PF01494.14 EPE33331.1 - 0.016 14.2 0.1 0.14 11.1 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EPE33331.1 - 0.033 12.6 0.0 4.8 5.5 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.11 EPE33331.1 - 0.079 12.3 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EPE33331.1 - 0.088 11.4 0.0 3.8 6.0 0.0 2.7 2 1 1 3 3 3 0 Tryptophan halogenase NmrA PF05368.8 EPE33332.1 - 5.6e-25 87.9 0.0 7.1e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE33332.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE33332.1 - 0.022 13.4 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EPE33332.1 - 0.14 12.4 0.0 0.75 10.1 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EPE33332.1 - 0.15 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 KR domain DUF485 PF04341.7 EPE33332.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 SLBP_RNA_bind PF15247.1 EPE33333.1 - 1 9.1 6.8 15 5.4 2.4 2.5 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Glyco_transf_21 PF13506.1 EPE33334.1 - 3.4e-10 39.4 0.0 0.00036 19.8 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EPE33334.1 - 7.8e-09 35.6 0.0 2e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EPE33334.1 - 0.00073 19.2 0.0 0.0074 15.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 tRNA_int_endo PF01974.12 EPE33335.1 - 3.7e-22 77.9 0.2 7e-22 77.0 0.2 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EPE33335.1 - 0.00014 21.3 0.0 0.056 13.0 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain HET PF06985.6 EPE33336.1 - 1.1e-19 70.9 11.6 4.8e-17 62.4 1.8 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.19 EPE33338.1 - 6.5e-25 87.3 16.5 7.7e-14 51.4 4.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Rubella_E2 PF05749.6 EPE33338.1 - 0.04 13.1 0.9 0.13 11.4 0.8 1.7 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 DUF4577 PF15145.1 EPE33338.1 - 0.095 12.6 0.1 0.55 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) DUF4229 PF14012.1 EPE33338.1 - 0.34 10.8 8.1 1.2 9.0 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Otopetrin PF03189.8 EPE33338.1 - 4.5 6.1 8.5 0.36 9.7 0.8 2.5 2 1 0 2 2 2 0 Otopetrin Ank_2 PF12796.2 EPE33339.1 - 4.3e-212 687.2 35.8 2.6e-21 75.7 0.0 19.0 3 3 17 21 21 21 21 Ankyrin repeats (3 copies) Ank PF00023.25 EPE33339.1 - 2.2e-172 551.0 20.7 2e-10 39.9 0.0 36.0 37 0 0 37 37 37 32 Ankyrin repeat Ank_4 PF13637.1 EPE33339.1 - 2.4e-124 403.8 24.9 1.6e-10 41.1 0.1 25.5 11 8 16 28 28 28 25 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE33339.1 - 4.5e-122 395.3 33.4 2.2e-09 37.2 0.0 29.6 7 6 24 32 32 32 28 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE33339.1 - 1.6e-112 355.9 18.9 4e-06 26.5 0.0 35.5 37 0 0 37 37 37 23 Ankyrin repeat ZZ PF00569.12 EPE33339.1 - 7.8e-05 22.1 6.5 0.00019 20.9 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type Sulfate_transp PF00916.15 EPE33339.1 - 0.0014 17.6 0.2 0.26 10.2 0.0 2.3 2 0 0 2 2 2 2 Sulfate transporter family AAA PF00004.24 EPE33340.1 - 3.9e-16 59.4 0.0 8e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CPT PF07931.7 EPE33340.1 - 0.0014 18.2 0.0 0.045 13.3 0.0 2.5 1 1 1 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.1 EPE33340.1 - 0.0028 17.8 0.2 0.052 13.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EPE33340.1 - 0.0034 17.3 0.0 0.0094 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EPE33340.1 - 0.036 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EPE33340.1 - 0.038 13.7 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EPE33340.1 - 0.052 13.2 0.0 0.19 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 EPE33340.1 - 0.095 12.1 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 EPE33340.1 - 0.2 11.1 0.0 0.41 10.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 EPE33340.1 - 2.8 8.7 5.9 2 9.2 1.0 3.1 3 1 0 3 3 3 0 AAA domain Ank_2 PF12796.2 EPE33342.1 - 1e-60 202.0 9.7 4.5e-17 62.1 0.2 6.4 3 1 4 8 8 8 6 Ankyrin repeats (3 copies) Ank PF00023.25 EPE33342.1 - 3e-44 146.6 13.1 1.1e-06 28.1 0.0 11.4 10 1 1 11 11 11 8 Ankyrin repeat Ank_4 PF13637.1 EPE33342.1 - 9.1e-37 124.8 6.6 2.9e-06 27.6 0.0 7.8 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE33342.1 - 1.2e-35 117.9 10.6 0.0011 19.0 0.0 11.2 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.1 EPE33342.1 - 5.3e-32 109.1 12.7 3.2e-06 27.1 0.1 8.7 4 1 4 8 8 8 7 Ankyrin repeats (many copies) NACHT PF05729.7 EPE33342.1 - 3.6e-08 33.2 0.0 9.3e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPE33342.1 - 9.5e-05 22.4 0.0 0.0004 20.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE33342.1 - 0.0018 18.4 0.0 0.0068 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPE33342.1 - 0.048 13.5 0.0 0.45 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EPE33342.1 - 0.07 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase p450 PF00067.17 EPE33343.1 - 6e-73 245.9 0.0 8e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF605 PF04652.11 EPE33345.1 - 4.8 6.4 12.1 6.5 6.0 8.4 1.1 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_16 PF00722.16 EPE33346.1 - 2e-10 40.2 0.8 2e-10 40.2 0.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Ldh_2 PF02615.9 EPE33346.1 - 0.044 12.5 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase Ery_res_leader1 PF08051.6 EPE33346.1 - 4.7 7.0 6.0 4.5 7.0 0.1 2.5 2 0 0 2 2 2 0 Erythromycin resistance leader peptide HET PF06985.6 EPE33347.1 - 5.5e-33 114.0 0.6 9.1e-33 113.3 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nbas_N PF15492.1 EPE33347.1 - 0.036 13.1 0.4 0.69 8.9 0.0 2.6 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal AMP-binding PF00501.23 EPE33348.1 - 4.6e-28 97.7 0.0 2.7e-25 88.6 0.0 2.1 1 1 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 EPE33348.1 - 1.3e-21 76.7 0.0 5e-20 71.4 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EPE33348.1 - 5.9e-09 35.7 0.0 9.2e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE33348.1 - 0.00042 20.3 0.0 0.00076 19.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EPE33348.1 - 0.048 13.9 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ank_2 PF12796.2 EPE33349.1 - 2.9e-50 168.5 10.3 4.1e-15 55.8 0.1 5.1 2 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPE33349.1 - 1.4e-39 131.9 20.1 5.6e-08 32.2 0.1 10.0 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 EPE33349.1 - 7.1e-34 115.5 6.6 3.1e-11 43.4 0.0 6.7 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE33349.1 - 1.2e-31 105.5 7.1 0.0015 18.6 0.0 9.0 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 EPE33349.1 - 1e-24 85.9 6.3 8.3e-07 29.0 0.0 8.4 3 2 7 10 10 10 8 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.1 EPE33350.1 - 0.00044 20.3 3.9 0.28 11.6 0.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE33350.1 - 0.01 16.1 6.5 1 9.8 1.0 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ank_2 PF12796.2 EPE33351.1 - 2.4e-48 162.4 5.9 4.8e-16 58.8 0.3 4.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPE33351.1 - 8.8e-40 132.5 18.8 2.5e-07 30.1 0.0 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 EPE33351.1 - 1e-37 127.8 2.7 1.2e-08 35.2 0.0 5.5 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE33351.1 - 5.2e-30 100.5 9.9 0.0003 20.7 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 EPE33351.1 - 1.3e-27 95.1 7.9 3.1e-08 33.5 0.1 6.5 2 2 6 8 8 8 7 Ankyrin repeats (many copies) DUF3447 PF11929.3 EPE33351.1 - 0.036 13.8 0.0 0.44 10.3 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) zf-C2H2 PF00096.21 EPE33352.1 - 4.1e-07 29.9 9.4 0.00028 21.0 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE33352.1 - 1.3e-06 28.2 8.9 0.0067 16.6 1.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC PF01530.13 EPE33352.1 - 2.2 8.0 7.3 2.3 7.9 0.0 3.0 3 0 0 3 3 3 0 Zinc finger, C2HC type zf-H2C2_2 PF13465.1 EPE33352.1 - 5 7.6 15.3 3 8.2 1.7 4.0 4 0 0 4 4 4 0 Zinc-finger double domain Beta_helix PF13229.1 EPE33353.1 - 1.7e-14 53.8 18.2 2.2e-12 47.0 4.5 2.9 1 1 2 3 3 3 2 Right handed beta helix region NosD PF05048.8 EPE33353.1 - 8.8e-11 41.4 10.3 5e-08 32.4 1.2 2.5 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) HOK_GEF PF01848.11 EPE33353.1 - 0.33 10.3 2.9 0.64 9.3 2.0 1.4 1 0 0 1 1 1 0 Hok/gef family Pkinase PF00069.20 EPE33355.1 - 1.9e-17 63.2 0.0 2.6e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE33355.1 - 3.1e-13 49.3 0.0 4.2e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPE33355.1 - 3.1e-05 23.1 0.1 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPE33355.1 - 0.011 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EPE33355.1 - 0.098 12.3 0.1 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.2 EPE33356.1 - 5.9e-18 65.0 3.2 2e-15 56.8 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE33356.1 - 5.6e-17 61.7 0.5 5.8e-09 36.2 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EPE33356.1 - 2.4e-15 55.4 3.7 2.7e-11 42.6 0.1 3.3 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EPE33356.1 - 3e-15 55.8 3.7 2.7e-11 43.3 0.2 3.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE33356.1 - 1.6e-13 49.4 1.8 4.8e-08 32.5 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeat DUF917 PF06032.7 EPE33357.1 - 5.4e-93 311.3 0.1 2.7e-91 305.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EPE33357.1 - 6.4e-40 137.0 3.8 2.1e-39 135.3 2.7 1.9 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EPE33357.1 - 1.3e-20 73.6 0.2 4.4e-20 71.9 0.1 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region CCDC-167 PF15188.1 EPE33357.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Acetyltransf_1 PF00583.19 EPE33358.1 - 7.3e-09 35.5 0.1 1.3e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE33358.1 - 1.8e-06 28.0 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE33358.1 - 4e-06 26.9 0.0 7.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE33358.1 - 1.9e-05 24.5 0.1 3.2e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE33358.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EPE33358.1 - 0.12 12.1 0.1 0.54 10.0 0.0 2.0 1 1 1 2 2 2 0 FR47-like protein 2-Hacid_dh_C PF02826.14 EPE33360.1 - 1.8e-44 151.0 0.0 7.5e-44 149.0 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPE33360.1 - 5.4e-05 22.6 0.0 7.1e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ADH_N PF08240.7 EPE33361.1 - 4.9e-27 93.8 2.0 1e-26 92.8 1.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE33361.1 - 1.5e-16 60.1 0.1 2.3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ATP-synt_G PF04718.10 EPE33362.1 - 8.8e-30 103.4 1.0 9.7e-29 100.0 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF883 PF05957.8 EPE33362.1 - 0.0019 18.5 2.6 0.0041 17.4 1.8 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) EspB PF05802.6 EPE33362.1 - 0.0093 14.9 8.9 0.29 10.0 6.1 2.1 2 0 0 2 2 2 1 Enterobacterial EspB protein Senescence PF06911.7 EPE33362.1 - 0.025 14.2 7.9 0.17 11.5 4.8 2.1 2 0 0 2 2 2 0 Senescence-associated protein DivIVA PF05103.8 EPE33362.1 - 0.25 11.4 4.3 0.41 10.6 3.0 1.3 1 0 0 1 1 1 0 DivIVA protein Glyco_hydro_2 PF00703.16 EPE33363.1 - 2e-05 25.0 0.0 5.2e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EPE33363.1 - 0.034 13.0 0.0 0.21 10.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain DNA_pol_viral_N PF00242.12 EPE33364.1 - 0.33 9.9 4.6 0.44 9.5 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain AA_permease_2 PF13520.1 EPE33365.1 - 1.4e-49 168.8 59.4 1.7e-49 168.5 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE33365.1 - 5.5e-27 94.2 49.7 8e-27 93.7 34.4 1.2 1 0 0 1 1 1 1 Amino acid permease zf-C2H2 PF00096.21 EPE33366.1 - 0.09 13.1 1.8 0.31 11.4 1.3 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type TRI12 PF06609.8 EPE33366.1 - 0.13 10.4 0.5 0.2 9.7 0.4 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Patatin PF01734.17 EPE33367.1 - 6.2e-27 94.8 0.0 1e-26 94.1 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Fungal_trans_2 PF11951.3 EPE33368.1 - 0.0082 14.7 0.0 0.012 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3253 PF11625.3 EPE33370.1 - 7e-20 70.7 0.0 9.2e-20 70.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) MARVEL PF01284.18 EPE33371.1 - 0.00018 21.3 8.7 0.00039 20.2 6.0 1.6 1 1 0 1 1 1 1 Membrane-associating domain Glycos_transf_4 PF00953.16 EPE33371.1 - 1.2 8.9 6.4 2.2 8.0 4.4 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 4 DUF3445 PF11927.3 EPE33372.1 - 6.1e-80 268.2 0.0 1.6e-78 263.5 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3445) DnaJ PF00226.26 EPE33373.1 - 5.9e-27 93.1 2.1 9.1e-27 92.5 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EPE33373.1 - 1.3e-14 54.0 16.1 2.2e-14 53.2 11.2 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EPE33373.1 - 3.9e-13 49.1 0.0 2.4e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EPE33373.1 - 0.0053 16.4 7.2 0.14 11.8 0.8 2.2 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EPE33373.1 - 0.35 10.7 7.1 2.2 8.1 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon OB_NTP_bind PF07717.11 EPE33374.1 - 7.8e-27 93.3 0.0 2.2e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPE33374.1 - 1.4e-24 86.0 0.2 1.4e-24 86.0 0.1 3.0 4 0 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPE33374.1 - 3.3e-13 49.2 0.0 1e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPE33374.1 - 0.0001 22.4 0.0 0.00036 20.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EPE33374.1 - 0.0002 20.8 0.1 0.00095 18.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 EPE33374.1 - 0.00097 18.1 0.0 0.0024 16.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EPE33374.1 - 0.086 12.7 0.9 0.8 9.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EPE33374.1 - 0.18 12.1 0.0 0.18 12.1 0.0 2.6 2 1 0 2 2 2 0 ABC transporter RhgB_N PF09284.5 EPE33375.1 - 1.4e-98 329.1 5.3 2.2e-98 328.5 3.7 1.2 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EPE33375.1 - 5.7e-61 204.9 0.3 6.4e-58 195.0 0.0 3.0 3 0 0 3 3 3 2 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EPE33375.1 - 1.9e-14 53.5 1.5 1.9e-14 53.5 1.1 2.7 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II Methyltransf_23 PF13489.1 EPE33376.1 - 3.3e-14 52.9 0.0 4.5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE33376.1 - 2.9e-08 34.1 0.0 3.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE33376.1 - 2.1e-05 24.1 0.0 2.7e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE33376.1 - 5.5e-05 23.7 0.0 7.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE33376.1 - 0.0002 21.7 0.0 0.00029 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EPE33376.1 - 0.0028 16.4 0.0 0.0035 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EPE33376.1 - 0.0033 16.5 0.0 0.0044 16.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EPE33376.1 - 0.0098 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 EPE33376.1 - 0.1 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 EPE33376.1 - 0.11 12.9 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TFIIIC_sub6 PF10419.4 EPE33377.1 - 8.2e-11 41.1 0.0 1.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit zf-CCHC PF00098.18 EPE33380.1 - 0.00093 19.0 2.8 0.00093 19.0 1.9 2.3 2 0 0 2 2 2 1 Zinc knuckle DUF3245 PF11595.3 EPE33381.1 - 0.27 11.4 0.7 0.43 10.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Sugar_tr PF00083.19 EPE33382.1 - 4.1e-127 424.4 23.2 4.7e-127 424.2 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE33382.1 - 5.3e-16 58.2 53.9 3.3e-15 55.6 21.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.7 EPE33382.1 - 2 7.3 9.1 1.5 7.8 4.8 1.9 1 1 1 2 2 2 0 Emopamil binding protein APG5 PF04106.7 EPE33383.1 - 1.5e-34 119.2 0.0 1.7e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg5 2OG-FeII_Oxy_3 PF13640.1 EPE33384.1 - 0.00024 21.5 0.1 0.00052 20.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPE33384.1 - 0.0089 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Herpes_gE PF02480.11 EPE33385.1 - 0.16 10.1 0.0 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4360 PF14273.1 EPE33386.1 - 1e-68 230.6 2.8 1.3e-68 230.3 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) hGDE_N PF14699.1 EPE33386.1 - 0.1 12.4 0.1 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme DUF1518 PF07469.7 EPE33386.1 - 2.7 8.1 7.4 2.1 8.5 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) HET PF06985.6 EPE33387.1 - 0.038 14.1 0.1 0.086 12.9 0.0 1.6 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.19 EPE33388.1 - 3.9e-37 126.9 26.3 3.7e-21 75.2 9.9 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CYSTM PF12734.2 EPE33389.1 - 0.15 12.1 0.5 0.15 12.1 0.4 2.2 3 0 0 3 3 3 0 Cysteine-rich TM module stress tolerance Bim_N PF06773.6 EPE33389.1 - 0.24 11.1 6.3 0.72 9.6 4.4 1.8 1 0 0 1 1 1 0 Bim protein N-terminus CDC50 PF03381.10 EPE33391.1 - 4.7e-98 327.7 0.0 5.6e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SAE2 PF08573.5 EPE33392.1 - 8.4e-25 87.2 0.1 8.4e-25 87.2 0.1 3.1 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus TPR_12 PF13424.1 EPE33392.1 - 5.5e-15 55.0 21.8 0.00017 21.4 0.2 6.6 4 1 1 6 6 6 6 Tetratricopeptide repeat NB-ARC PF00931.17 EPE33392.1 - 1.3e-06 27.4 0.0 6.8e-06 25.1 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.1 EPE33392.1 - 0.0055 16.3 3.5 12 5.9 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Choline_kin_N PF04428.9 EPE33392.1 - 0.0066 15.8 0.0 1.5 8.3 0.0 3.0 2 0 0 2 2 2 1 Choline kinase N terminus TPR_2 PF07719.12 EPE33392.1 - 0.026 14.4 12.9 19 5.4 0.0 7.8 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF972 PF06156.8 EPE33392.1 - 0.27 11.5 7.2 0.17 12.2 2.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Apc3 PF12895.2 EPE33392.1 - 0.29 11.2 9.8 4.4 7.5 0.1 4.5 3 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EPE33392.1 - 0.34 10.6 4.7 14 5.4 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Adeno_PIX PF03955.9 EPE33392.1 - 4.2 7.9 5.8 3.1 8.3 1.5 2.6 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Amino_oxidase PF01593.19 EPE33393.1 - 5.2e-36 124.6 0.0 3.2e-17 62.7 0.0 2.2 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPE33393.1 - 5.7e-14 51.8 0.0 1.2e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE33393.1 - 1e-07 31.2 0.1 8.8e-07 28.1 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPE33393.1 - 4e-07 30.3 0.5 1.4e-06 28.6 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE33393.1 - 6.2e-06 26.4 0.1 8.3e-05 22.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE33393.1 - 1.7e-05 24.7 0.0 0.00036 20.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE33393.1 - 0.00019 21.2 1.3 0.021 14.5 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EPE33393.1 - 0.0002 19.9 0.2 0.00036 19.1 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EPE33393.1 - 0.0018 17.4 0.1 0.0028 16.7 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EPE33393.1 - 0.0035 16.2 0.1 0.005 15.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.14 EPE33393.1 - 0.013 13.7 0.2 0.028 12.6 0.0 1.5 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.14 EPE33393.1 - 0.014 14.4 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EPE33393.1 - 0.033 13.8 0.1 0.076 12.6 0.0 1.6 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EPE33393.1 - 0.06 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 EPE33393.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 EPE33393.1 - 0.15 11.4 0.2 0.37 10.2 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EPE33393.1 - 0.16 12.2 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Sugar_tr PF00083.19 EPE33394.1 - 5.4e-120 401.0 29.5 6.3e-120 400.7 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE33394.1 - 9e-20 70.6 30.8 9e-20 70.6 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mem_trans PF03547.13 EPE33394.1 - 0.92 7.7 5.1 0.14 10.4 0.2 2.0 3 0 0 3 3 3 0 Membrane transport protein DHquinase_I PF01487.10 EPE33396.1 - 1.4e-58 198.2 0.0 1.9e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase DUF3970 PF13113.1 EPE33396.1 - 0.034 13.8 0.1 0.068 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) SPT16 PF08644.6 EPE33397.1 - 6.2e-59 198.1 0.2 6.2e-59 198.1 0.2 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EPE33397.1 - 5.5e-53 178.8 0.1 2.2e-52 176.8 0.1 2.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EPE33397.1 - 1e-23 84.0 0.0 1.8e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EPE33397.1 - 2.2e-21 75.6 0.1 7.5e-21 73.9 0.1 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like RhodobacterPufX PF11511.3 EPE33398.1 - 0.00076 18.8 1.4 0.0022 17.3 0.3 2.0 2 0 0 2 2 2 1 Intrinsic membrane protein PufX HET PF06985.6 EPE33399.1 - 1.6e-24 86.6 0.1 3.5e-24 85.5 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAM195 PF14799.1 EPE33403.1 - 0.036 13.9 0.0 0.085 12.7 0.0 1.7 1 0 0 1 1 1 0 FAM195 family Laminin_G_3 PF13385.1 EPE33404.1 - 0.012 15.8 1.0 0.018 15.2 0.7 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily SLAC1 PF03595.12 EPE33405.1 - 2.4e-74 249.9 48.5 2.7e-74 249.7 33.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel GerPB PF10803.3 EPE33406.1 - 0.033 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Spore germination GerPB Methyltransf_22 PF13383.1 EPE33407.1 - 7.8e-27 94.3 0.0 1.1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EPE33407.1 - 5.4e-09 36.2 0.0 7.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Fungal_trans PF04082.13 EPE33408.1 - 5.4e-28 97.5 0.0 1.2e-27 96.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE33408.1 - 0.0006 19.6 13.2 0.0012 18.7 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 EPE33408.1 - 0.61 8.8 2.5 1.3 7.7 1.7 1.5 1 0 0 1 1 1 0 Clusterin Opy2 PF09463.5 EPE33408.1 - 3.3 7.8 7.4 7.2 6.7 5.1 1.5 1 0 0 1 1 1 0 Opy2 protein EthD PF07110.6 EPE33409.1 - 0.00066 20.5 0.0 0.21 12.5 0.0 2.2 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.1 EPE33409.1 - 0.0058 16.8 0.0 0.06 13.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4286) APH PF01636.18 EPE33411.1 - 1.1e-14 54.7 0.0 2.5e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE33411.1 - 0.00048 19.7 0.1 0.00089 18.8 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EPE33411.1 - 0.074 12.3 0.1 2.9 7.1 0.1 2.5 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 EPE33411.1 - 0.087 11.8 0.0 2.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 EPE33412.1 - 2.2e-11 43.9 0.1 6.5e-11 42.4 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE33412.1 - 6.8e-06 25.8 0.1 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE33412.1 - 7e-05 22.3 0.0 0.00015 21.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPE33412.1 - 0.0015 17.4 0.0 0.0023 16.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EPE33412.1 - 0.0052 16.8 0.0 0.0094 16.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RgpF PF05045.7 EPE33413.1 - 0.092 11.2 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Rhamnan synthesis protein F MFS_1 PF07690.11 EPE33414.1 - 1.8e-37 128.8 35.2 1.8e-37 128.8 24.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE33414.1 - 9.5e-06 24.0 0.7 9.5e-06 24.0 0.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE33414.1 - 0.00024 19.8 43.7 0.0062 15.1 30.3 3.8 1 1 0 1 1 1 1 Sugar (and other) transporter OEP PF02321.13 EPE33415.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein MARVEL PF01284.18 EPE33416.1 - 0.74 9.6 7.0 20 4.9 6.0 2.2 1 1 1 2 2 2 0 Membrane-associating domain CcmD PF04995.9 EPE33416.1 - 1.5 8.5 0.0 1.5 8.5 0.0 3.0 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) DUF2681 PF10883.3 EPE33416.1 - 6.2 7.0 6.8 0.93 9.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) HET PF06985.6 EPE33417.1 - 9.3e-25 87.4 0.0 2.7e-24 85.8 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 EPE33418.1 - 4e-17 62.2 0.0 2e-16 60.0 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EPE33418.1 - 5.3e-06 26.7 0.5 3.1e-05 24.2 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE33418.1 - 0.011 14.7 0.4 0.045 12.6 0.2 1.9 1 1 2 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE33418.1 - 0.03 14.3 0.1 0.063 13.3 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TPR_8 PF13181.1 EPE33418.1 - 0.061 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DSBA PF01323.15 EPE33418.1 - 0.089 12.3 0.1 7 6.1 0.0 2.2 2 0 0 2 2 2 0 DSBA-like thioredoxin domain 3HCDH_N PF02737.13 EPE33418.1 - 0.1 12.2 0.1 1 8.9 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.27 EPE33420.1 - 4.2e-11 42.2 0.0 0.0025 17.6 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat TPR_11 PF13414.1 EPE33422.1 - 5.3e-14 51.6 4.3 1.7e-07 30.7 0.1 3.6 1 1 4 5 5 5 3 TPR repeat TPR_19 PF14559.1 EPE33422.1 - 1.5e-09 38.0 0.9 9.4e-09 35.4 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE33422.1 - 1e-08 35.0 3.8 0.0001 22.6 0.1 4.3 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE33422.1 - 1.3e-08 35.2 4.4 1.2e-05 25.8 0.2 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPE33422.1 - 6.7e-08 31.8 0.1 0.00022 20.9 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EPE33422.1 - 4.7e-06 26.3 0.8 0.0023 17.9 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPE33422.1 - 2.5e-05 23.7 0.2 0.00075 19.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 EPE33422.1 - 5.9e-05 23.1 1.0 0.0013 18.7 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPE33422.1 - 0.00066 19.5 0.2 0.12 12.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPE33422.1 - 0.002 18.4 0.3 3.5 8.3 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPE33422.1 - 0.0043 16.8 0.2 0.015 15.1 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPE33422.1 - 0.0083 15.7 0.1 0.47 10.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE33422.1 - 0.051 13.4 0.2 6.1 6.8 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EPE33422.1 - 0.096 12.8 0.1 0.27 11.3 0.0 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Adaptin_N PF01602.15 EPE33423.1 - 7.7e-81 271.9 0.0 1.4e-80 271.1 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region DUF2893 PF11459.3 EPE33423.1 - 0.094 12.5 0.2 19 5.1 0.0 3.9 4 0 0 4 4 4 0 Protein of unknwon function (DUF2893) SMAP PF15477.1 EPE33424.1 - 1.5e-16 60.3 7.5 1.5e-16 60.3 5.2 6.5 4 2 0 4 4 4 1 Small acidic protein family LAGLIDADG_WhiA PF14527.1 EPE33424.1 - 0.014 15.2 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain RAMP4 PF06624.7 EPE33425.1 - 1.9e-07 30.5 0.0 1.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Methyltransf_12 PF08242.7 EPE33429.1 - 4e-16 59.2 0.0 1.1e-15 57.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE33429.1 - 5.2e-12 45.7 0.0 8.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE33429.1 - 7.8e-11 42.2 0.0 1.7e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE33429.1 - 1.6e-10 41.3 0.0 3.7e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE33429.1 - 6.3e-10 39.6 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE33429.1 - 7.4e-10 38.6 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE33429.1 - 1.1e-06 27.9 0.0 1.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EPE33429.1 - 6.3e-06 26.2 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EPE33429.1 - 7.3e-05 21.8 0.0 0.22 10.4 0.0 2.4 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.9 EPE33429.1 - 0.00014 21.2 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 EPE33429.1 - 0.00074 20.3 0.0 0.0029 18.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DUF3419 PF11899.3 EPE33429.1 - 0.017 13.8 0.0 0.025 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_16 PF10294.4 EPE33429.1 - 0.036 13.5 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EPE33429.1 - 0.043 12.9 0.0 0.098 11.8 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB Polyketide_cyc PF03364.15 EPE33430.1 - 4e-21 75.3 0.0 9.1e-21 74.2 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EPE33430.1 - 0.027 14.6 0.1 3 8.0 0.0 2.2 1 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport YrhK PF14145.1 EPE33433.1 - 1.6e-08 34.0 17.8 1.5e-06 27.7 0.1 4.5 4 2 0 4 4 4 3 YrhK-like protein Ank_2 PF12796.2 EPE33434.1 - 5.3e-49 164.5 1.1 1.6e-11 44.3 0.0 8.2 8 2 1 9 9 9 5 Ankyrin repeats (3 copies) Ank PF00023.25 EPE33434.1 - 5.5e-43 142.6 17.9 1.7e-06 27.5 0.0 12.6 12 0 0 12 12 12 8 Ankyrin repeat Ank_3 PF13606.1 EPE33434.1 - 4.6e-33 109.9 18.7 2.4e-05 24.1 0.0 12.2 14 0 0 14 14 14 7 Ankyrin repeat Ank_4 PF13637.1 EPE33434.1 - 3.7e-31 106.9 14.4 2.1e-07 31.2 0.4 10.1 9 2 2 11 11 11 7 Ankyrin repeats (many copies) Pkinase PF00069.20 EPE33434.1 - 2.4e-27 95.7 0.0 4.4e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.1 EPE33434.1 - 2.9e-27 94.0 13.4 4.8e-08 33.0 0.0 9.0 7 2 2 9 9 9 6 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 EPE33434.1 - 1.7e-17 63.3 0.0 4.6e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Sel1 PF08238.7 EPE33434.1 - 0.0011 19.5 0.2 0.0042 17.6 0.0 2.1 2 0 0 2 2 2 1 Sel1 repeat Kdo PF06293.9 EPE33434.1 - 0.04 12.9 0.4 0.24 10.4 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EPE33435.1 - 4.2e-05 22.7 0.0 0.00034 19.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EPE33435.1 - 0.0085 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ldh_2 PF02615.9 EPE33436.1 - 3.6e-96 321.8 0.0 4.1e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Acetyltransf_1 PF00583.19 EPE33437.1 - 2.3e-08 33.9 0.0 3.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EPE33437.1 - 0.00068 19.4 0.0 0.00095 19.0 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 EPE33437.1 - 0.0071 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain COG5 PF10392.4 EPE33439.1 - 0.00019 21.4 0.2 0.00019 21.4 0.2 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 UQ_con PF00179.21 EPE33440.1 - 3.3e-09 36.3 0.0 7.4e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PARP PF00644.15 EPE33440.1 - 1.6e-07 30.9 0.1 3.9e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain RWD PF05773.17 EPE33440.1 - 0.012 15.5 0.0 0.037 13.9 0.0 1.9 1 0 0 1 1 1 0 RWD domain Sigma70_ner PF04546.8 EPE33440.1 - 0.019 14.5 1.7 0.036 13.6 1.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region STAG PF08514.6 EPE33441.1 - 3.8e-24 84.6 0.0 3.8e-24 84.6 0.0 2.3 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.1 EPE33441.1 - 0.0001 22.5 0.3 0.0013 19.0 0.0 3.1 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EPE33441.1 - 0.018 15.0 0.1 82 3.6 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat p450 PF00067.17 EPE33442.1 - 1.9e-68 231.0 0.0 2.6e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 EPE33442.1 - 1e-25 90.5 0.1 6.3e-25 87.9 0.0 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Methyltransf_2 PF00891.13 EPE33443.1 - 2.4e-34 118.5 0.0 4.3e-34 117.7 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EPE33443.1 - 3.3e-06 27.6 0.0 7.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE33443.1 - 0.00052 19.7 0.0 0.00091 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE33443.1 - 0.00093 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE33443.1 - 0.00094 19.6 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NUMOD1 PF07453.8 EPE33443.1 - 0.0087 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 NUMOD1 domain CENP-B_N PF04218.8 EPE33443.1 - 0.068 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain CheR PF01739.13 EPE33443.1 - 0.077 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain HTH_38 PF13936.1 EPE33443.1 - 0.096 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 EPE33443.1 - 0.1 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AMP-binding PF00501.23 EPE33445.1 - 2.3e-41 141.5 0.0 4.6e-41 140.5 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EPE33445.1 - 4.7e-28 98.9 0.0 9e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EPE33445.1 - 5.5e-06 26.5 0.3 1.2e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EPE33445.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE33445.1 - 0.076 12.7 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EPE33446.1 - 2e-37 128.7 0.0 2.4e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EPE33446.1 - 1.2e-06 27.5 0.0 1.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 EPE33446.1 - 0.00026 19.7 0.0 0.0011 17.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPE33446.1 - 0.0036 17.0 0.0 0.0055 16.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipoprotein_21 PF14041.1 EPE33446.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 LppP/LprE lipoprotein NB-ARC PF00931.17 EPE33447.1 - 3.9e-18 65.2 0.0 6.4e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EPE33447.1 - 3.4e-09 36.9 1.1 1.6e-08 34.7 0.3 2.5 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EPE33447.1 - 2.2e-05 24.1 0.1 5.1e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EPE33447.1 - 0.00037 20.6 0.0 0.0015 18.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain tRNA-synt_2 PF00152.15 EPE33448.1 - 2.5e-75 253.3 0.0 5e-75 252.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EPE33448.1 - 2e-12 46.5 0.2 3.9e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EPE33448.1 - 3.2e-05 23.7 0.1 6.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Abhydrolase_3 PF07859.8 EPE33449.1 - 7.7e-39 133.4 0.2 1e-26 93.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 EPE33449.1 - 3e-08 32.8 0.2 7.8e-08 31.4 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EPE33449.1 - 0.015 15.1 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 EPE33449.1 - 0.029 13.8 1.0 0.2 11.0 0.7 2.0 1 1 0 1 1 1 0 Putative esterase DUF2974 PF11187.3 EPE33449.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HET PF06985.6 EPE33450.1 - 1.2e-32 112.9 1.3 1.9e-32 112.2 0.9 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_2 PF00891.13 EPE33451.1 - 8.5e-38 129.9 0.0 1.7e-37 128.8 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EPE33451.1 - 0.0004 20.9 0.0 0.00084 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EPE33451.1 - 0.0091 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EPE33451.1 - 0.013 15.2 0.0 0.031 13.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain CheR PF01739.13 EPE33451.1 - 0.08 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.9 EPE33451.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Epiglycanin_C PF14654.1 EPE33452.1 - 0.0093 15.9 0.6 0.019 14.9 0.4 1.4 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region GMC_oxred_N PF00732.14 EPE33453.1 - 1e-33 116.7 0.0 2.2e-31 109.1 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE33453.1 - 1.9e-29 102.8 0.0 3e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EPE33453.1 - 6.5e-05 22.8 0.1 0.00019 21.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE33453.1 - 0.00016 20.6 0.0 0.00029 19.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EPE33453.1 - 0.0057 15.1 0.0 0.0085 14.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EPE33453.1 - 0.006 16.6 0.1 0.4 10.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE33453.1 - 0.009 14.9 0.4 0.015 14.2 0.1 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EPE33453.1 - 0.025 13.4 1.0 0.037 12.9 0.2 1.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPE33453.1 - 0.026 14.4 0.1 0.059 13.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPE33453.1 - 0.066 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EPE33453.1 - 0.074 12.4 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EPE33453.1 - 0.13 12.6 0.1 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EPE33453.1 - 0.19 11.4 0.1 0.37 10.5 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 EPE33453.1 - 0.23 10.5 0.0 0.42 9.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Ebp2 PF05890.7 EPE33454.1 - 6.2e-91 304.4 19.1 6.2e-91 304.4 13.2 1.9 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 PQ-loop PF04193.9 EPE33457.1 - 6.2e-38 128.1 13.4 1e-18 66.5 1.7 2.7 2 0 0 2 2 2 2 PQ loop repeat BT1 PF03092.11 EPE33457.1 - 0.068 11.8 0.0 0.11 11.1 0.0 1.3 1 1 0 1 1 1 0 BT1 family WD40 PF00400.27 EPE33458.1 - 1.3e-51 170.6 29.2 1.1e-11 44.0 0.1 11.9 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.7 EPE33458.1 - 8.6e-29 99.6 0.0 1.3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EPE33458.1 - 2.7e-07 30.4 1.2 0.054 13.2 0.1 5.6 4 2 2 6 6 6 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPE33458.1 - 0.00052 18.2 2.8 1.6 6.8 0.2 3.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 EPE33458.1 - 0.0022 17.1 0.1 3.8 6.5 0.0 3.4 3 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 EPE33458.1 - 0.041 11.7 0.0 4.3 5.0 0.0 2.6 2 1 0 2 2 2 0 IKI3 family Utp13 PF08625.6 EPE33458.1 - 0.13 11.8 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain Septin PF00735.13 EPE33459.1 - 2e-115 384.6 0.2 3e-115 384.1 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EPE33459.1 - 2.2e-07 30.8 0.0 4.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPE33459.1 - 3.8e-06 26.4 0.1 8e-05 22.1 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPE33459.1 - 2e-05 23.8 0.0 5.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EPE33459.1 - 0.0028 18.1 0.0 0.0093 16.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EPE33459.1 - 0.0031 17.1 0.1 0.006 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPE33459.1 - 0.0036 17.4 0.4 0.013 15.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.11 EPE33459.1 - 0.0048 16.0 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 EPE33459.1 - 0.0063 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EPE33459.1 - 0.0067 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 EPE33459.1 - 0.014 14.7 0.1 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein T2SE PF00437.15 EPE33459.1 - 0.024 13.5 0.3 0.073 11.9 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.17 EPE33459.1 - 0.026 13.9 0.6 0.073 12.4 0.2 1.9 2 1 0 2 2 2 0 Ras family Dynamin_N PF00350.18 EPE33459.1 - 0.043 13.6 5.4 0.88 9.3 0.0 2.9 2 1 1 3 3 3 0 Dynamin family NACHT PF05729.7 EPE33459.1 - 0.043 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EPE33459.1 - 0.062 13.5 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.21 EPE33459.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 EPE33459.1 - 0.083 11.8 0.9 0.12 11.3 0.6 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Arch_ATPase PF01637.13 EPE33459.1 - 0.09 12.4 2.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 EPE33459.1 - 0.1 12.1 0.7 2.9 7.3 0.2 2.6 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EPE33459.1 - 0.11 12.4 1.5 0.32 10.9 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 EPE33459.1 - 0.12 11.8 0.7 9.4 5.6 0.1 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EPE33459.1 - 0.15 10.7 2.1 0.95 8.1 0.0 2.7 3 0 0 3 3 3 0 ArgK protein RNA_helicase PF00910.17 EPE33459.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Myc-LZ PF02344.10 EPE33459.1 - 2.5 7.7 6.8 0.96 9.1 0.3 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain BCDHK_Adom3 PF10436.4 EPE33460.1 - 1.4e-49 167.8 0.2 3e-49 166.6 0.2 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EPE33460.1 - 1.3e-09 37.7 0.0 2.6e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EPE33460.1 - 0.051 13.2 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CRAL_TRIO PF00650.15 EPE33461.1 - 4.5e-13 49.0 0.0 7.3e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPE33461.1 - 0.0096 16.0 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain USP7_ICP0_bdg PF12436.3 EPE33462.1 - 7.7e-77 257.8 0.0 1.4e-74 250.4 0.0 3.3 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EPE33462.1 - 3.9e-70 235.5 5.1 4.2e-68 228.9 0.7 2.9 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 EPE33462.1 - 1.2e-52 178.6 1.4 2.2e-52 177.8 1.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPE33462.1 - 1.3e-27 96.9 0.0 2.2e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EPE33462.1 - 4.8e-10 39.7 0.3 6.7e-08 32.8 0.0 3.8 3 1 0 4 4 4 1 MATH domain RA PF00788.18 EPE33462.1 - 0.0014 19.1 0.0 0.038 14.4 0.0 3.2 4 0 0 4 4 4 1 Ras association (RalGDS/AF-6) domain SKIP_SNW PF02731.10 EPE33463.1 - 2.7e-67 225.1 4.5 2.7e-67 225.1 3.1 2.5 2 0 0 2 2 2 1 SKIP/SNW domain EMP24_GP25L PF01105.19 EPE33463.1 - 1.2e-33 116.3 1.1 1.2e-33 116.3 0.8 1.7 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD Serglycin PF04360.7 EPE33463.1 - 1.8 8.2 8.3 3.9 7.2 0.5 3.4 4 0 0 4 4 4 0 Serglycin FAM60A PF15396.1 EPE33463.1 - 2.1 8.0 10.6 5.3 6.7 7.4 1.7 1 0 0 1 1 1 0 Protein Family FAM60A PAF-AH_p_II PF03403.8 EPE33466.1 - 1.9e-45 154.8 0.0 1.1e-44 152.3 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EPE33466.1 - 8.4e-10 38.5 0.0 2.3e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EPE33466.1 - 1.5e-06 27.3 0.0 4.2e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPE33466.1 - 2e-06 26.8 0.0 3.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.2 EPE33466.1 - 2.5e-06 27.5 0.1 5.7e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE33466.1 - 0.0048 16.7 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase DLH PF01738.13 EPE33466.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family NACHT PF05729.7 EPE33467.1 - 2.1e-07 30.7 0.1 8.7e-07 28.7 0.1 2.1 2 0 0 2 2 2 1 NACHT domain DUF676 PF05057.9 EPE33467.1 - 7.3e-05 22.1 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EPE33467.1 - 0.00012 21.7 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.1 EPE33467.1 - 0.00025 21.1 0.0 0.00093 19.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE33467.1 - 0.00028 21.0 0.0 0.0039 17.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EPE33467.1 - 0.00034 20.1 0.0 0.00059 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 EPE33467.1 - 0.0076 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 EPE33467.1 - 0.013 15.8 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Abhydrolase_6 PF12697.2 EPE33467.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family NB-ARC PF00931.17 EPE33467.1 - 0.023 13.5 0.0 0.078 11.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.1 EPE33467.1 - 0.038 14.2 0.0 0.2 11.9 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 EPE33467.1 - 0.062 14.1 0.7 0.26 12.1 0.1 2.4 2 1 0 2 2 1 0 AAA domain DUF87 PF01935.12 EPE33467.1 - 0.088 12.6 0.1 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_33 PF13671.1 EPE33467.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPE33467.1 - 0.13 11.8 0.1 0.33 10.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EPE33467.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase MFS_1 PF07690.11 EPE33468.1 - 8.1e-33 113.5 32.4 1.1e-32 113.1 22.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CAF1A PF12253.3 EPE33469.1 - 1.7e-24 85.7 4.9 1.7e-24 85.7 3.4 3.0 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EPE33469.1 - 0.0023 17.3 68.9 0.0075 15.6 47.8 1.8 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF262 PF03235.9 EPE33469.1 - 0.11 12.3 5.9 0.29 11.0 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF262 Mitofilin PF09731.4 EPE33469.1 - 0.15 10.6 28.1 0.23 10.0 19.4 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Borrelia_P83 PF05262.6 EPE33469.1 - 1.1 7.4 40.1 1.8 6.7 27.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein SAPS PF04499.10 EPE33469.1 - 2.2 6.8 13.0 4 5.9 9.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DBINO PF13892.1 EPE33469.1 - 4.4 7.3 39.5 11 6.0 27.4 1.6 1 0 0 1 1 1 0 DNA-binding domain DUF4407 PF14362.1 EPE33469.1 - 7.8 5.3 22.6 14 4.5 15.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 EPE33469.1 - 7.8 4.8 24.4 12 4.1 16.9 1.2 1 0 0 1 1 1 0 AAA domain Dimeth_Pyl PF09505.5 EPE33471.1 - 0.00032 19.1 0.6 0.00037 18.8 0.4 1.0 1 0 0 1 1 1 1 Dimethylamine methyltransferase (Dimeth_PyL) HET PF06985.6 EPE33473.1 - 5.6e-21 75.1 0.0 1.3e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) tRNA-synt_1e PF01406.14 EPE33475.1 - 4.2e-99 331.4 0.0 1.5e-98 329.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.6 EPE33475.1 - 1.2e-06 28.6 0.0 4.1e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 DALR domain tRNA-synt_1g PF09334.6 EPE33475.1 - 3.4e-05 22.6 0.6 0.09 11.4 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.16 EPE33475.1 - 0.0044 15.7 2.4 0.13 10.9 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain GCD14 PF08704.5 EPE33476.1 - 4e-62 209.9 5.4 4.6e-43 147.4 0.1 3.9 3 2 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EPE33476.1 - 0.00064 19.7 0.0 0.0075 16.2 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Abhydrolase_2 PF02230.11 EPE33477.1 - 1.3e-14 54.2 0.0 1.6e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EPE33477.1 - 0.00013 21.9 0.1 0.00019 21.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE33477.1 - 0.0088 15.8 0.0 0.015 15.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3759 PF12585.3 EPE33478.1 - 3.9e-40 135.6 5.4 5.1e-40 135.2 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) NADPH_Ox PF08414.5 EPE33478.1 - 0.061 13.4 0.4 11 6.1 0.1 2.3 1 1 1 2 2 2 0 Respiratory burst NADPH oxidase Peptidase_M18 PF02127.10 EPE33479.1 - 4.6e-130 433.9 0.0 5.3e-130 433.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) ABM PF03992.11 EPE33480.1 - 0.0013 18.6 0.0 0.0017 18.3 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase adh_short PF00106.20 EPE33481.1 - 1.2e-11 44.8 0.1 1.8e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE33481.1 - 8.7e-05 22.2 0.2 0.00015 21.4 0.1 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EPE33481.1 - 0.0032 17.2 0.0 0.012 15.3 0.0 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPE33481.1 - 0.016 15.2 0.3 0.45 10.4 0.2 2.3 1 1 0 1 1 1 0 NADH(P)-binding DJ-1_PfpI PF01965.19 EPE33481.1 - 0.027 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Aa_trans PF01490.13 EPE33482.1 - 2e-79 267.0 23.4 2.4e-79 266.7 16.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 EPE33482.1 - 3.4 7.3 10.2 1.6 8.4 1.0 3.6 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase WW PF00397.21 EPE33484.1 - 3.6e-05 23.5 1.2 0.0001 22.1 0.9 1.8 1 0 0 1 1 1 1 WW domain Metallophos PF00149.23 EPE33487.1 - 1.6e-41 141.9 0.9 2.4e-41 141.3 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase bZIP_2 PF07716.10 EPE33488.1 - 7.2e-08 32.1 14.6 7.2e-08 32.1 10.1 2.0 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EPE33488.1 - 0.0018 18.2 17.5 0.17 11.8 0.8 2.3 1 1 1 2 2 2 2 bZIP transcription factor Voldacs PF03517.8 EPE33489.1 - 1.2e-28 99.6 0.4 2.3e-28 98.7 0.3 1.5 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling OPT PF03169.10 EPE33490.1 - 3.7e-129 431.9 43.9 4.2e-129 431.7 30.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PLDc_2 PF13091.1 EPE33491.1 - 9.6e-13 47.9 0.0 5.1e-06 26.2 0.0 3.5 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EPE33491.1 - 1.8e-12 46.6 0.7 2.5e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif 3Beta_HSD PF01073.14 EPE33493.1 - 6.4e-53 179.2 0.0 8.1e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE33493.1 - 2.8e-30 105.5 0.0 3.4e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPE33493.1 - 3.2e-15 55.7 0.3 1.6e-13 50.1 0.2 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EPE33493.1 - 8.1e-10 38.0 0.4 4.2e-09 35.7 0.3 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EPE33493.1 - 2.5e-09 37.4 0.0 3.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EPE33493.1 - 6.9e-06 25.1 0.0 1.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EPE33493.1 - 0.00024 21.0 0.6 0.00073 19.4 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE33493.1 - 0.091 12.4 0.4 0.68 9.5 0.3 2.3 1 1 0 1 1 1 0 KR domain DUF1853 PF08907.6 EPE33494.1 - 0.15 11.1 0.5 1.5 7.9 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1853) TRH PF05438.7 EPE33495.1 - 0.0028 17.0 1.2 0.0036 16.7 0.8 1.2 1 0 0 1 1 1 1 Thyrotropin-releasing hormone (TRH) Haemagg_act PF05860.8 EPE33495.1 - 0.016 14.9 0.6 0.26 11.0 0.2 2.3 1 1 1 2 2 2 0 haemagglutination activity domain Phycoerythr_ab PF02972.9 EPE33495.1 - 0.043 13.4 2.6 5.2 6.7 0.1 3.1 1 1 2 3 3 3 0 Phycoerythrin, alpha/beta chain Zn_clus PF00172.13 EPE33496.1 - 1.8e-08 34.1 14.7 3.5e-08 33.2 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE33496.1 - 1.4e-07 30.6 4.6 1.2e-06 27.5 1.2 2.3 1 1 0 2 2 2 2 Fungal specific transcription factor domain Sigma70_ECF PF07638.6 EPE33496.1 - 0.087 12.4 0.0 0.84 9.2 0.0 2.4 3 0 0 3 3 3 0 ECF sigma factor DUF3328 PF11807.3 EPE33497.1 - 1.8e-05 24.5 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans PF04082.13 EPE33499.1 - 3.7e-21 75.1 0.9 5.6e-21 74.5 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPE33499.1 - 2.9e-11 42.9 7.4 4.7e-05 23.4 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE33499.1 - 2.5e-10 39.9 7.9 4.5e-06 26.6 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE33499.1 - 1.5e-05 25.0 8.0 0.0056 16.9 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EPE33499.1 - 0.0089 15.9 4.8 0.018 14.9 0.2 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger Elf1 PF05129.8 EPE33499.1 - 0.036 13.7 0.6 0.074 12.7 0.5 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 EPE33499.1 - 0.1 12.7 0.6 0.27 11.3 0.4 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EPE33499.1 - 0.15 12.2 2.1 0.81 9.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EPE33499.1 - 0.55 10.0 4.2 8.4 6.2 0.0 2.7 2 1 1 3 3 3 0 BED zinc finger HET PF06985.6 EPE33500.1 - 3.5e-22 79.0 10.2 2.1e-19 70.0 1.2 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF791 PF05631.9 EPE33501.1 - 1.3e-67 227.9 3.5 1.9e-67 227.4 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EPE33501.1 - 1.6e-22 79.7 16.0 2.4e-22 79.1 11.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EPE33501.1 - 0.0025 17.5 3.2 0.41 10.4 0.0 3.5 3 0 0 3 3 3 2 MFS_1 like family EXS PF03124.9 EPE33502.1 - 2.6e-94 316.1 32.8 3.2e-94 315.7 22.8 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EPE33502.1 - 2.8e-50 171.6 0.0 2.9e-49 168.3 0.0 2.3 2 1 0 2 2 2 1 SPX domain FUR PF01475.14 EPE33502.1 - 0.074 12.9 0.1 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Ferric uptake regulator family MatE PF01554.13 EPE33503.1 - 1.1e-08 34.9 23.9 3.3e-06 26.8 2.0 3.8 4 0 0 4 4 4 3 MatE Polysacc_synt_C PF14667.1 EPE33503.1 - 0.003 17.3 4.4 0.003 17.3 3.0 3.6 3 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain SprT-like PF10263.4 EPE33504.1 - 4e-06 26.5 0.0 6.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.1 EPE33504.1 - 0.032 14.3 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Effector protein TRAUB PF08164.7 EPE33504.1 - 0.099 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal APH PF01636.18 EPE33505.1 - 3.6e-11 43.2 0.0 1.4e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE33505.1 - 6.3e-08 32.4 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EPE33505.1 - 0.08 11.5 0.0 0.24 9.9 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) DUF1845 PF08900.6 EPE33505.1 - 0.099 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) Metallothio_Euk PF12749.2 EPE33506.1 - 5.4 7.1 44.4 11 6.1 23.1 2.1 1 1 1 2 2 2 0 Eukaryotic metallothionein ABM PF03992.11 EPE33507.1 - 8.2e-06 25.7 2.2 0.016 15.1 0.3 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase YcgL PF05166.8 EPE33507.1 - 0.036 14.1 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 YcgL domain MFS_1 PF07690.11 EPE33508.1 - 4.9e-35 120.8 29.9 6.9e-35 120.3 20.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily C1_1 PF00130.17 EPE33509.1 - 0.053 13.2 3.1 0.16 11.6 2.1 1.9 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_trans_1_3 PF13528.1 EPE33509.1 - 0.16 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 adh_short_C2 PF13561.1 EPE33510.1 - 1.7e-27 96.7 1.2 2.7e-27 96.0 0.9 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE33510.1 - 3.2e-23 82.4 2.6 8.6e-23 81.0 1.8 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE33510.1 - 3e-10 40.0 1.3 7.3e-09 35.5 0.2 2.1 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.14 EPE33510.1 - 0.0019 17.3 0.0 0.0047 16.0 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 EPE33510.1 - 0.0068 15.8 0.2 0.11 11.9 0.1 2.3 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.18 EPE33510.1 - 0.0084 15.8 0.7 0.054 13.2 0.2 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EPE33510.1 - 0.01 14.8 0.2 0.012 14.6 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EPE33510.1 - 0.026 14.3 1.2 0.057 13.2 0.2 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EPE33510.1 - 0.039 13.5 0.3 0.073 12.7 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PNK3P PF08645.6 EPE33510.1 - 0.06 12.7 0.0 0.21 11.0 0.0 1.8 1 1 1 2 2 2 0 Polynucleotide kinase 3 phosphatase Peptidase_C11 PF03415.9 EPE33510.1 - 0.076 11.9 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Clostripain family NAD_binding_7 PF13241.1 EPE33510.1 - 0.079 13.2 0.2 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FLILHELTA PF10306.4 EPE33512.1 - 1.7e-30 104.8 0.0 6.9e-30 102.9 0.0 1.8 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EPE33512.1 - 0.0038 17.4 0.0 0.0053 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) NDK PF00334.14 EPE33513.1 - 4.6e-55 185.0 0.0 5.6e-55 184.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 EPE33514.1 - 2.2e-154 514.5 3.1 2.8e-154 514.1 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EPE33514.1 - 7.6e-24 83.3 1.8 7.7e-24 83.3 0.1 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like Phosphonate-bd PF12974.2 EPE33515.1 - 3.2e-05 23.4 0.0 7.7e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_11 PF13531.1 EPE33515.1 - 0.013 15.1 0.0 0.23 11.0 0.0 2.5 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein NMT1 PF09084.6 EPE33515.1 - 0.014 15.0 0.0 0.095 12.2 0.0 2.0 1 1 0 1 1 1 0 NMT1/THI5 like DUF3834 PF12916.2 EPE33515.1 - 0.068 12.1 0.0 0.14 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3834) UQ_con PF00179.21 EPE33516.1 - 1.1e-49 167.4 0.0 1.3e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPE33516.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B TP6A_N PF04406.9 EPE33517.1 - 3.3e-19 68.3 0.0 6.9e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Prenyltrans PF00432.16 EPE33518.1 - 1.7e-28 97.8 4.3 4.5e-09 35.7 0.0 4.1 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPE33518.1 - 2.1e-23 82.8 2.8 1.1e-11 45.1 0.0 5.7 3 1 1 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPE33518.1 - 2.4e-23 82.2 1.9 4.3e-14 52.4 0.1 6.5 5 2 1 7 7 7 4 Prenyltransferase-like Pec_lyase PF09492.5 EPE33518.1 - 4.3e-08 32.6 2.4 0.021 13.9 0.1 5.0 4 2 1 5 5 5 3 Pectic acid lyase Jacalin PF01419.12 EPE33519.1 - 3.4e-05 23.7 0.1 0.00015 21.6 0.0 2.1 1 1 0 1 1 1 1 Jacalin-like lectin domain SGS PF05002.10 EPE33520.1 - 4.8e-29 99.9 3.9 1.2e-28 98.6 2.7 1.8 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EPE33520.1 - 1.3e-15 57.7 0.0 2.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EPE33520.1 - 1.5e-08 34.1 1.7 3.9e-07 29.6 0.2 2.4 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 EPE33520.1 - 7.5e-08 31.7 2.3 0.016 15.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPE33520.1 - 3.2e-07 29.6 1.0 0.017 14.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE33520.1 - 4.1e-05 24.1 6.1 0.001 19.6 0.3 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE33520.1 - 0.00025 21.4 0.5 1.1 10.0 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPE33520.1 - 0.018 14.9 5.2 0.33 10.9 1.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2057 PF09829.4 EPE33520.1 - 0.025 14.2 1.8 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) TPR_19 PF14559.1 EPE33520.1 - 0.037 14.3 0.2 5 7.5 0.1 2.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPE33520.1 - 0.067 12.9 0.1 4.7 7.2 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPE33520.1 - 0.089 13.2 5.1 5.5 7.7 1.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EPE33520.1 - 0.13 12.4 0.4 0.29 11.2 0.3 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Alpha-amylase PF00128.19 EPE33521.1 - 4.5e-15 55.8 0.0 1.7e-14 53.9 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_21 PF03370.8 EPE33521.1 - 3.3e-10 39.9 0.5 6.8e-10 38.9 0.3 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Inhibitor_I42 PF09394.5 EPE33521.1 - 0.03 14.6 0.2 0.12 12.7 0.1 2.1 1 0 0 1 1 1 0 Chagasin family peptidase inhibitor I42 MscL PF01741.13 EPE33522.1 - 3.6e-16 59.4 0.1 7.7e-16 58.4 0.1 1.5 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.17 EPE33522.1 - 0.0054 16.4 2.2 0.011 15.4 1.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Yip1 PF04893.12 EPE33522.1 - 0.022 14.2 0.4 0.03 13.8 0.3 1.2 1 0 0 1 1 1 0 Yip1 domain zf-BED PF02892.10 EPE33522.1 - 0.025 14.3 2.4 0.047 13.4 1.7 1.4 1 0 0 1 1 1 0 BED zinc finger p450 PF00067.17 EPE33523.1 - 1.5e-48 165.5 0.0 1.8e-45 155.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Lipase_GDSL_2 PF13472.1 EPE33524.1 - 7.3e-13 49.0 0.0 1.1e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE33524.1 - 2.9e-05 24.0 0.4 8.8e-05 22.4 0.2 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Fungal_trans_2 PF11951.3 EPE33525.1 - 0.00036 19.2 0.0 0.00071 18.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EPE33526.1 - 1.6e-17 63.7 8.0 2.9e-17 62.9 5.5 1.3 1 1 0 1 1 1 1 RTA1 like protein ADH_zinc_N PF00107.21 EPE33528.1 - 1.2e-08 34.5 0.0 3e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE33528.1 - 5.8e-08 32.4 0.1 3.1e-07 30.1 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DXP_reductoisom PF02670.11 EPE33528.1 - 0.067 13.7 0.0 0.41 11.1 0.0 2.1 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NmrA PF05368.8 EPE33528.1 - 0.08 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Glyco_hydro_18 PF00704.23 EPE33529.1 - 6.4e-11 42.2 0.0 5.7e-10 39.1 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 MFS_1 PF07690.11 EPE33531.1 - 7.6e-35 120.2 34.7 7.6e-35 120.2 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE33531.1 - 4.5e-10 38.6 9.3 4.5e-10 38.6 6.5 3.1 2 2 0 2 2 2 1 Sugar (and other) transporter DUF3584 PF12128.3 EPE33534.1 - 0.0017 15.7 1.4 0.0024 15.3 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 EPE33534.1 - 0.016 15.0 4.1 0.03 14.1 2.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 EPE33534.1 - 0.077 12.7 4.0 0.12 12.1 2.1 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 EPE33534.1 - 0.085 11.8 1.9 0.13 11.2 1.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 EPE33534.1 - 0.15 11.8 4.1 0.3 10.8 2.8 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EPE33534.1 - 0.84 9.4 7.6 0.37 10.6 1.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.15 EPE33534.1 - 0.91 9.3 5.3 2.1 8.1 1.5 2.3 1 1 1 2 2 2 0 Prefoldin subunit DivIC PF04977.10 EPE33534.1 - 4.8 6.7 6.8 17 4.9 1.5 2.4 1 1 1 2 2 2 0 Septum formation initiator GAGA_bind PF06217.7 EPE33535.1 - 0.054 13.4 45.6 0.069 13.1 0.7 4.7 1 1 3 5 5 5 0 GAGA binding protein-like family 2OG-FeII_Oxy PF03171.15 EPE33537.1 - 0.00037 20.7 0.0 0.00076 19.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Allantoicase PF03561.10 EPE33538.1 - 3.3e-96 318.8 0.1 9.7e-52 174.4 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Amidohydro_4 PF13147.1 EPE33539.1 - 7.5e-26 91.7 0.0 1.1e-25 91.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EPE33539.1 - 8.9e-14 51.0 1.5 1.8e-12 46.8 0.4 2.7 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EPE33539.1 - 1.4e-09 38.0 0.0 8.4e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EPE33539.1 - 0.017 14.3 0.7 0.46 9.6 0.1 2.5 1 1 1 2 2 2 0 Amidohydrolase family IU_nuc_hydro PF01156.14 EPE33540.1 - 5.6e-77 259.0 0.0 7.3e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase AA_permease_2 PF13520.1 EPE33541.1 - 3e-66 223.7 47.2 3.8e-66 223.3 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE33541.1 - 2.1e-23 82.4 42.3 3e-23 81.9 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1469 PF07332.6 EPE33541.1 - 0.54 9.9 23.7 0.059 13.0 1.5 5.4 5 1 0 5 5 5 0 Protein of unknown function (DUF1469) His_Phos_1 PF00300.17 EPE33542.1 - 1e-20 74.4 0.0 1.3e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AMP-binding PF00501.23 EPE33543.1 - 1.2e-72 244.6 0.0 1.5e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE33543.1 - 6e-15 55.9 0.0 1.3e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.21 EPE33544.1 - 2.8e-70 236.6 0.0 5.2e-70 235.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EPE33544.1 - 2.2e-55 187.9 0.0 3.4e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EPE33544.1 - 2.5e-53 180.4 0.2 5.2e-53 179.4 0.1 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EPE33544.1 - 2.6e-53 181.4 0.0 4.5e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EPE33544.1 - 2.3e-43 147.9 0.1 5.9e-43 146.6 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPE33544.1 - 6.2e-35 119.6 0.2 1.9e-34 118.0 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EPE33544.1 - 3.1e-05 23.0 0.1 6.2e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 EPE33544.1 - 0.0022 16.9 0.0 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPE33544.1 - 0.0023 16.7 0.0 0.0045 15.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ACP_syn_III PF08545.5 EPE33544.1 - 0.097 12.3 1.2 0.25 11.0 0.5 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP-binding PF00550.20 EPE33544.1 - 0.097 12.9 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EPE33544.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DNA_gyraseB_C PF00986.16 EPE33544.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Rhomboid PF01694.17 EPE33545.1 - 4e-33 114.5 14.4 4e-33 114.5 10.0 2.1 2 0 0 2 2 2 1 Rhomboid family TATR PF03430.8 EPE33546.1 - 0.97 7.9 5.8 1.4 7.4 4.0 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF1180 PF06679.7 EPE33546.1 - 1.3 8.8 5.6 0.35 10.7 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) MFS_1 PF07690.11 EPE33550.1 - 6.1e-47 160.0 62.6 7.2e-47 159.7 41.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE33550.1 - 3.8e-17 61.7 14.2 1.7e-16 59.5 9.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE33550.1 - 6.8e-14 51.2 13.3 6.8e-14 51.2 9.2 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Kinocilin PF15033.1 EPE33550.1 - 0.15 11.6 2.0 6.7 6.2 0.0 3.4 3 0 0 3 3 3 0 Kinocilin protein Sulfatase PF00884.18 EPE33551.1 - 5.5e-54 183.4 0.0 7e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EPE33551.1 - 3.5e-23 81.1 0.5 7.3e-23 80.1 0.3 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EPE33551.1 - 1.6e-09 37.5 0.1 4.4e-08 32.8 0.1 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EPE33551.1 - 0.052 12.9 0.0 1.2 8.5 0.0 2.3 2 1 0 2 2 2 0 Metalloenzyme superfamily FSH1 PF03959.8 EPE33552.1 - 7.5e-30 103.9 0.0 6.1e-29 100.9 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EPE33552.1 - 0.0033 17.1 0.0 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF3530 PF12048.3 EPE33552.1 - 0.07 12.1 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Abhydrolase_2 PF02230.11 EPE33552.1 - 0.11 11.9 0.3 0.64 9.4 0.1 2.3 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase ketoacyl-synt PF00109.21 EPE33553.1 - 3.9e-72 242.7 0.0 7e-72 241.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EPE33553.1 - 1.9e-61 206.8 0.1 8e-61 204.8 0.0 2.2 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EPE33553.1 - 9.1e-54 182.9 0.0 2.6e-53 181.4 0.0 1.8 1 1 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EPE33553.1 - 2.1e-48 164.4 0.4 6.9e-48 162.7 0.0 2.2 2 0 0 2 2 1 1 short chain dehydrogenase PS-DH PF14765.1 EPE33553.1 - 8.6e-44 149.8 0.0 1.4e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EPE33553.1 - 3.2e-36 123.7 0.1 9e-36 122.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EPE33553.1 - 1.4e-19 69.9 0.3 9e-19 67.3 0.0 2.6 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EPE33553.1 - 2.2e-17 63.3 0.0 6.6e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE33553.1 - 3.6e-13 49.5 0.0 7.5e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE33553.1 - 1.5e-11 44.1 0.0 4.1e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EPE33553.1 - 1.6e-10 41.9 0.0 1.5e-09 38.8 0.0 2.7 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EPE33553.1 - 2e-09 37.7 0.0 5.8e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EPE33553.1 - 5.9e-08 32.4 0.1 1.3e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EPE33553.1 - 1.3e-05 25.7 0.0 5.7e-05 23.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE33553.1 - 0.00034 19.8 0.1 0.0015 17.7 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EPE33553.1 - 0.00055 20.1 0.0 0.0025 18.0 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 EPE33553.1 - 0.0057 17.0 0.0 0.021 15.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain YjeF_N PF03853.10 EPE33553.1 - 0.064 12.8 0.1 1.5 8.3 0.0 3.1 4 0 0 4 4 3 0 YjeF-related protein N-terminus NAD_binding_10 PF13460.1 EPE33553.1 - 0.084 12.8 0.6 2.1 8.3 0.1 2.7 2 0 0 2 2 2 0 NADH(P)-binding DNA_gyraseB_C PF00986.16 EPE33553.1 - 0.16 11.7 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus ATP13 PF12921.2 EPE33554.1 - 1.3e-25 89.1 0.0 2.3e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 EPE33554.1 - 2.1e-07 30.8 0.4 0.0098 15.8 0.1 2.9 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 EPE33554.1 - 0.00049 20.1 0.1 0.0074 16.4 0.0 3.1 3 0 0 3 3 3 1 Pentatricopeptide repeat domain LSM PF01423.17 EPE33555.1 - 3.1e-17 61.8 0.0 6.4e-17 60.8 0.0 1.5 1 1 0 1 1 1 1 LSM domain GTP_EFTU PF00009.22 EPE33556.1 - 1.4e-21 76.8 0.0 2.4e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPE33556.1 - 1.3e-14 54.1 0.0 3.2e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPE33556.1 - 1.8e-11 43.9 1.8 2.1e-10 40.5 0.8 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EPE33556.1 - 0.0032 16.9 1.2 0.24 10.8 0.1 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EPE33556.1 - 0.011 16.2 0.0 0.12 12.9 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 EPE33556.1 - 0.019 14.8 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EPE33556.1 - 0.16 11.6 2.9 0.13 11.9 0.2 2.2 2 1 0 2 2 2 0 Elongation factor Tu domain 4 Kinetochor_Ybp2 PF08568.5 EPE33557.1 - 1.8e-131 439.4 0.4 2.4e-131 439.0 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin CMD PF02627.15 EPE33558.1 - 0.033 14.0 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Dsh_C PF12316.3 EPE33561.1 - 1.2 9.1 12.4 2.2 8.3 8.6 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal zf-C2H2_4 PF13894.1 EPE33562.1 - 4.7e-09 35.9 28.2 0.077 13.3 1.1 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE33562.1 - 8.6e-07 28.9 30.9 0.027 14.8 2.2 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.2 EPE33562.1 - 0.00029 20.9 20.7 0.029 14.5 0.9 5.1 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPE33562.1 - 0.0012 18.9 21.0 0.87 9.8 1.6 4.8 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EPE33562.1 - 0.044 13.6 0.2 0.044 13.6 0.2 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.1 EPE33562.1 - 0.11 12.1 3.4 10 5.9 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EPE33562.1 - 0.19 11.3 3.6 9.8 5.8 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 EPE33562.1 - 1.2 9.3 21.4 5 7.2 1.2 4.7 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 EPE33562.1 - 1.7 8.8 17.5 0.063 13.4 1.4 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 EPE33562.1 - 6.9 5.0 15.0 0.057 11.9 2.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-DHHC PF01529.15 EPE33563.1 - 5.3e-44 149.6 5.5 1e-43 148.7 3.8 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 EPE33563.1 - 0.073 12.9 7.2 0.18 11.6 5.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon UQ_con PF00179.21 EPE33564.1 - 1.1e-21 76.7 0.0 1.8e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPE33564.1 - 0.044 13.6 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 RWD domain SGL PF08450.7 EPE33565.1 - 7.1e-05 22.3 0.0 0.00018 20.9 0.0 1.6 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Zn_clus PF00172.13 EPE33566.1 - 5e-06 26.3 11.7 9.5e-06 25.4 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE33566.1 - 1.8e-05 23.5 5.5 6e-05 21.8 0.6 2.4 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zip PF02535.17 EPE33568.1 - 0.047 12.6 1.1 0.16 10.9 0.2 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter DUF3397 PF11877.3 EPE33568.1 - 0.76 9.7 11.0 1.1 9.3 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) DUF4387 PF14330.1 EPE33569.1 - 1.3e-30 105.6 0.0 2.7e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 EPE33569.1 - 4e-11 41.9 0.0 2e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) MFS_1 PF07690.11 EPE33570.1 - 1.9e-25 89.3 28.1 2.6e-25 88.9 19.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EPE33571.1 - 1e-07 31.1 2.6 1.8e-07 30.3 1.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE33571.1 - 1.5e-07 31.2 10.3 3e-07 30.2 6.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EPE33575.1 - 1.2e-33 116.3 0.0 1.5e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 EPE33576.1 - 6.2e-09 34.9 0.2 6.4e-07 28.3 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE33576.1 - 9.9e-06 25.3 12.7 1.7e-05 24.6 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EPE33577.1 - 9.8e-50 169.4 0.0 1.8e-49 168.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EPE33578.1 - 1.1e-20 73.6 0.0 2e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EPE33579.1 - 5.7e-34 117.4 0.1 6.7e-34 117.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Hexapep PF00132.19 EPE33579.1 - 0.06 12.8 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) HET PF06985.6 EPE33580.1 - 8.2e-32 110.2 0.1 1.3e-31 109.6 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4038 PF13204.1 EPE33580.1 - 0.084 12.1 0.1 4 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4038) PAN_4 PF14295.1 EPE33581.1 - 0.00016 21.2 0.3 0.00049 19.7 0.2 1.8 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 EPE33581.1 - 0.0028 17.4 0.2 0.0064 16.2 0.1 1.5 1 0 0 1 1 1 1 PAN-like domain YpzI PF14140.1 EPE33582.1 - 0.0016 17.8 3.7 7.2 6.1 0.1 3.7 3 0 0 3 3 3 3 YpzI-like protein Excalibur PF05901.6 EPE33582.1 - 0.0046 17.2 1.9 21 5.5 0.0 3.7 3 0 0 3 3 3 3 Excalibur calcium-binding domain CorA PF01544.13 EPE33584.1 - 1.9e-32 112.4 7.3 2e-28 99.2 2.2 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein CAP59_mtransfer PF11735.3 EPE33585.1 - 3.6e-61 206.4 0.0 5.5e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CorA PF01544.13 EPE33587.1 - 0.029 13.3 0.0 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF423 PF04241.10 EPE33588.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF423) TrkH PF02386.11 EPE33589.1 - 4.9e-19 68.1 13.5 6.4e-16 57.8 2.3 2.1 2 0 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.11 EPE33589.1 - 0.017 14.8 3.3 0.017 14.8 2.3 1.9 2 0 0 2 2 2 0 Ion channel SieB PF14163.1 EPE33589.1 - 0.4 10.2 5.5 4 6.9 0.1 2.5 2 0 0 2 2 2 0 Superinfection exclusion protein B TrkH PF02386.11 EPE33590.1 - 1.9e-50 171.4 0.4 2.3e-50 171.1 0.3 1.0 1 0 0 1 1 1 1 Cation transport protein SAYSvFN PF10260.4 EPE33590.1 - 0.0086 15.8 0.3 0.025 14.3 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) DUF1891 PF09004.5 EPE33590.1 - 0.056 12.8 0.3 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) DUF4381 PF14316.1 EPE33590.1 - 0.075 13.1 0.1 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DNA_pol_B PF00136.16 EPE33591.1 - 2.2e-145 485.0 1.8 3.6e-145 484.3 1.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EPE33591.1 - 5.6e-81 271.9 0.3 1.2e-80 270.8 0.2 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EPE33591.1 - 1.2e-23 82.9 6.6 3.8e-23 81.2 4.6 2.0 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 EPE33591.1 - 7.1e-05 22.4 0.0 0.0002 20.9 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EPE33591.1 - 0.00018 21.3 0.2 0.00064 19.5 0.2 2.1 1 1 0 1 1 1 1 RNase_H superfamily C1_1 PF00130.17 EPE33591.1 - 1.4 8.7 9.9 1.7 8.4 0.6 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Chitin_synth_1 PF01644.12 EPE33592.1 - 9.4e-71 236.8 0.0 1.4e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EPE33592.1 - 2.6e-26 91.1 0.0 5.1e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EPE33592.1 - 2.1e-22 79.2 0.4 2.9e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EPE33592.1 - 5.3e-15 55.6 0.2 5.3e-15 55.6 0.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPE33592.1 - 9.6e-14 51.7 0.0 2.9e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 GST_N_3 PF13417.1 EPE33593.1 - 1.1e-16 60.7 0.0 1.8e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPE33593.1 - 3e-14 52.7 0.0 4.9e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPE33593.1 - 9.5e-14 51.3 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPE33593.1 - 8.3e-12 44.9 0.0 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE33593.1 - 1e-07 31.7 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPE33593.1 - 7.2e-06 26.4 0.0 9.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DcpS_C PF11969.3 EPE33594.1 - 2.2e-16 60.1 4.0 1.5e-15 57.4 2.7 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EPE33594.1 - 6.4e-14 52.2 1.1 1.5e-13 51.0 0.8 1.6 1 1 0 1 1 1 1 HIT domain Gp37 PF09646.5 EPE33594.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Gp37 protein Bac_rhamnosid PF05592.6 EPE33595.1 - 1.6e-21 76.1 1.3 2.7e-20 72.0 0.4 2.4 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase HA2 PF04408.18 EPE33596.1 - 3e-18 65.7 1.5 1.1e-17 63.8 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPE33596.1 - 5.4e-15 55.0 0.0 3.7e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EPE33596.1 - 1.5e-13 50.5 0.0 3.5e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 EPE33596.1 - 2.1e-13 50.1 0.0 4.4e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EPE33596.1 - 5.2e-09 35.8 0.2 1.3e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPE33596.1 - 4.1e-05 23.7 0.2 0.00013 22.0 0.1 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EPE33596.1 - 0.00093 18.1 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DND1_DSRM PF14709.1 EPE33596.1 - 0.004 17.4 0.1 0.017 15.4 0.1 2.1 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.1 EPE33596.1 - 0.0061 16.0 0.1 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.10 EPE33596.1 - 0.0064 16.3 0.0 0.027 14.2 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit KaiC PF06745.8 EPE33596.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EPE33596.1 - 0.031 14.0 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 EPE33596.1 - 0.055 13.8 0.0 0.055 13.8 0.0 2.7 3 1 0 4 4 3 0 AAA domain DUF3632 PF12311.3 EPE33597.1 - 2.9e-14 53.2 5.6 4.5e-14 52.6 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Tub_2 PF04525.7 EPE33599.1 - 0.003 16.9 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Tubby C 2 Keratin PF02422.11 EPE33600.1 - 0.011 15.7 0.9 0.011 15.7 0.6 1.8 2 1 1 3 3 3 0 Keratin MBOAT_2 PF13813.1 EPE33601.1 - 4.2e-15 55.5 6.8 4.2e-15 55.5 4.7 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF2934 PF11154.3 EPE33602.1 - 0.36 10.2 1.6 0.4 10.0 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2934) Zn_clus PF00172.13 EPE33603.1 - 0.00059 19.6 14.9 0.001 18.9 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EPE33603.1 - 0.0079 15.4 5.1 0.047 12.9 0.0 3.1 3 0 0 3 3 3 2 Histone chaperone domain CHZ Cyclin_N PF00134.18 EPE33604.1 - 1.7e-43 147.2 0.1 3.1e-43 146.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPE33604.1 - 2.2e-33 114.6 0.0 5.3e-33 113.4 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Mito_carr PF00153.22 EPE33605.1 - 2.7e-74 244.9 0.2 4.5e-25 87.1 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 EPE33605.1 - 7.9e-14 50.2 5.2 4e-07 29.3 0.1 5.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.27 EPE33605.1 - 8.1e-13 46.6 7.0 5.4e-07 28.4 0.1 5.2 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.1 EPE33605.1 - 7.2e-11 42.0 7.4 2.5e-06 27.5 1.0 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EPE33605.1 - 8.7e-10 37.4 3.3 1.4e-05 24.2 0.1 4.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EPE33605.1 - 3.6e-08 32.8 6.3 1.4 8.6 0.1 5.6 4 2 2 6 6 6 5 EF-hand domain pair EF-hand_9 PF14658.1 EPE33605.1 - 0.014 15.2 0.0 1.7 8.6 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain FAD_binding_3 PF01494.14 EPE33606.1 - 9.7e-19 67.6 0.0 2.3e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EPE33606.1 - 8.3e-13 47.9 0.8 9.3e-07 28.0 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPE33606.1 - 3.8e-08 32.6 0.4 6.8e-07 28.5 0.2 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EPE33606.1 - 6e-08 31.5 0.8 2.3e-07 29.6 0.6 1.8 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EPE33606.1 - 2.1e-06 27.7 0.0 6.3e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE33606.1 - 7.5e-06 26.2 0.1 0.024 15.0 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE33606.1 - 1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE33606.1 - 0.00016 20.6 1.6 0.0003 19.7 0.6 1.8 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EPE33606.1 - 0.00019 21.3 0.3 0.00048 20.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EPE33606.1 - 0.00066 18.8 0.1 0.032 13.3 0.0 2.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EPE33606.1 - 0.002 16.8 0.5 0.013 14.1 0.1 2.1 1 1 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 EPE33606.1 - 0.0064 15.3 0.6 0.012 14.4 0.3 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EPE33606.1 - 0.026 13.6 0.2 0.039 13.0 0.2 1.2 1 0 0 1 1 1 0 Thi4 family RNA_pol_Rpc4 PF05132.9 EPE33607.1 - 2.6e-26 92.1 0.2 2.6e-26 92.1 0.1 3.0 3 2 0 3 3 3 1 RNA polymerase III RPC4 DUF1996 PF09362.5 EPE33608.1 - 1.3e-85 286.8 0.2 1.6e-85 286.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HET PF06985.6 EPE33609.1 - 6.6e-25 87.8 0.1 1.1e-24 87.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pyr_redox_3 PF13738.1 EPE33611.1 - 5.1e-24 85.4 0.2 2.4e-23 83.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE33611.1 - 1.3e-19 69.8 0.1 6.3e-17 60.9 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EPE33611.1 - 2.3e-13 50.4 0.0 2.9e-05 24.0 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPE33611.1 - 1.9e-12 46.8 0.0 1.2e-08 34.2 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EPE33611.1 - 5.4e-09 36.3 0.1 0.0043 17.4 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EPE33611.1 - 5.4e-08 32.1 0.2 0.00067 18.8 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EPE33611.1 - 6.7e-07 28.6 0.1 0.00095 18.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EPE33611.1 - 7.1e-07 29.1 0.0 5.4e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPE33611.1 - 4.7e-06 26.4 0.2 0.47 10.2 0.0 3.4 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EPE33611.1 - 1.4e-05 24.1 0.3 0.0054 15.6 0.0 3.5 4 0 0 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPE33611.1 - 4e-05 22.2 0.0 0.005 15.3 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein 3HCDH_N PF02737.13 EPE33611.1 - 8.3e-05 22.3 0.2 0.039 13.6 0.2 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EPE33611.1 - 9.9e-05 21.3 0.2 0.25 10.1 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A IlvN PF07991.7 EPE33611.1 - 0.00012 21.5 0.1 0.0032 16.8 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EPE33611.1 - 0.00014 22.2 0.0 2.3 8.6 0.1 3.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EPE33611.1 - 0.00014 21.8 0.4 0.13 12.2 0.0 2.9 3 0 0 3 3 3 1 TrkA-N domain Lycopene_cycl PF05834.7 EPE33611.1 - 0.00028 19.9 0.1 0.083 11.7 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPE33611.1 - 0.00089 18.2 0.0 0.016 14.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EPE33611.1 - 0.0012 19.0 0.0 0.22 11.8 0.1 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EPE33611.1 - 0.0016 18.5 0.2 1.4 9.0 0.1 2.9 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 EPE33611.1 - 0.0031 17.0 0.0 3.6 7.1 0.0 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EPE33611.1 - 0.0068 15.5 0.1 3.8 6.5 0.0 3.1 3 0 0 3 3 3 1 Thi4 family NAD_binding_2 PF03446.10 EPE33611.1 - 0.0088 15.8 0.1 0.95 9.2 0.1 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 EPE33611.1 - 0.0096 15.9 0.9 4.4 7.2 0.0 2.9 3 0 0 3 3 3 1 NADH(P)-binding ApbA PF02558.11 EPE33611.1 - 0.017 14.5 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.16 EPE33611.1 - 0.032 13.8 0.1 0.45 10.0 0.6 2.1 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_Gly3P_dh_N PF01210.18 EPE33611.1 - 0.035 13.8 0.4 0.42 10.3 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Mur_ligase PF01225.20 EPE33611.1 - 0.06 13.4 0.0 0.22 11.5 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, catalytic domain FAD_oxidored PF12831.2 EPE33611.1 - 0.063 12.3 0.0 0.56 9.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase AdoHcyase_NAD PF00670.16 EPE33611.1 - 0.13 12.1 1.0 1.6 8.5 0.3 2.5 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sugar_tr PF00083.19 EPE33612.1 - 8.1e-95 318.0 18.3 9.5e-95 317.8 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE33612.1 - 2.5e-21 75.8 54.3 1.3e-19 70.1 18.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily SNARE_assoc PF09335.6 EPE33612.1 - 0.0088 16.2 0.1 0.0088 16.2 0.1 3.7 3 1 0 4 4 4 2 SNARE associated Golgi protein Fungal_trans PF04082.13 EPE33613.1 - 1.3e-14 53.7 1.8 1.9e-14 53.2 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 EPE33614.1 - 1.9e-32 112.4 0.0 2.1e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE33614.1 - 0.00054 20.0 0.0 0.00091 19.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EPE33614.1 - 0.0022 17.0 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EPE33614.1 - 0.0026 16.5 0.0 0.0034 16.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE33614.1 - 0.0034 16.8 0.1 0.007 15.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EPE33614.1 - 0.049 13.2 0.2 0.11 12.1 0.1 1.6 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 EPE33614.1 - 0.064 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF1374 PF07118.6 EPE33615.1 - 0.008 16.2 0.6 0.55 10.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1374) PQ-loop PF04193.9 EPE33618.1 - 1.4e-31 107.8 16.5 1.6e-15 56.3 1.1 3.3 2 1 1 3 3 3 2 PQ loop repeat GtrA PF04138.9 EPE33618.1 - 0.018 14.9 0.4 0.018 14.9 0.3 2.9 1 1 2 3 3 3 0 GtrA-like protein CEP1-DNA_bind PF09287.5 EPE33618.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 CEP-1, DNA binding PLDc_N PF13396.1 EPE33618.1 - 0.46 10.2 6.1 5.2 6.8 0.2 3.7 3 0 0 3 3 3 0 Phospholipase_D-nuclease N-terminal PAF-AH_p_II PF03403.8 EPE33621.1 - 3.3e-14 51.9 0.0 2.7e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EPE33621.1 - 2.7e-11 43.3 0.1 4.2e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE33621.1 - 2.2e-07 30.9 0.1 3.4e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EPE33621.1 - 0.0001 21.2 0.0 0.00026 19.9 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPE33621.1 - 0.0091 14.8 0.3 0.14 10.9 0.2 2.1 1 1 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.3 EPE33621.1 - 0.12 12.1 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Fungal_trans_2 PF11951.3 EPE33622.1 - 2.1e-10 39.8 0.1 1.7e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Mating_C PF12737.2 EPE33622.1 - 0.094 11.5 0.5 0.13 11.1 0.4 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Dynamin_N PF00350.18 EPE33623.1 - 6.1e-43 146.5 0.0 1.1e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EPE33623.1 - 3e-11 42.6 0.0 3.1e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EPE33623.1 - 0.0035 17.2 0.0 0.0095 15.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPE33623.1 - 0.0047 17.4 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 EPE33623.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain GATase_4 PF13230.1 EPE33624.1 - 7.6e-15 54.3 0.0 8.4e-13 47.6 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EPE33624.1 - 1.9e-09 37.6 0.0 4.6e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EPE33624.1 - 0.00041 19.1 0.0 0.00086 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Cation_efflux PF01545.16 EPE33625.1 - 3e-33 115.1 9.9 4.2e-33 114.6 6.9 1.1 1 0 0 1 1 1 1 Cation efflux family PLAC8 PF04749.12 EPE33625.1 - 0.19 12.3 2.2 0.25 11.8 0.1 2.1 2 0 0 2 2 2 0 PLAC8 family Use1 PF09753.4 EPE33626.1 - 8.4 5.7 5.7 7.1 5.9 0.1 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 Sigma70_r2 PF04542.9 EPE33627.1 - 0.026 14.1 0.1 0.27 10.8 0.0 2.7 2 1 1 3 3 3 0 Sigma-70 region 2 AAA PF00004.24 EPE33628.1 - 1.7e-15 57.3 0.0 3.8e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EPE33628.1 - 0.0011 18.6 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EPE33628.1 - 0.0022 18.1 0.9 0.049 13.7 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EPE33628.1 - 0.011 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EPE33628.1 - 0.032 13.9 0.0 0.087 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EPE33628.1 - 0.043 13.7 0.4 0.89 9.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.21 EPE33628.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EPE33628.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPE33628.1 - 0.12 13.2 2.0 1.4 9.7 0.3 3.1 2 1 0 2 2 2 0 AAA domain Glyco_hydro_11 PF00457.12 EPE33629.1 - 9.8e-82 272.7 20.9 1.2e-81 272.5 14.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Myosin_tail_1 PF01576.14 EPE33631.1 - 0.0041 14.9 2.3 0.0063 14.3 1.6 1.2 1 0 0 1 1 1 1 Myosin tail CASP_C PF08172.7 EPE33631.1 - 0.058 12.4 0.3 0.11 11.4 0.2 1.5 1 0 0 1 1 1 0 CASP C terminal DUF4298 PF14131.1 EPE33631.1 - 0.085 12.7 0.7 0.18 11.6 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) DivIVA PF05103.8 EPE33631.1 - 7.9 6.5 11.1 0.071 13.1 1.2 2.2 3 0 0 3 3 3 0 DivIVA protein VCBS PF13517.1 EPE33632.1 - 1.9e-26 92.1 45.5 1.2e-09 38.3 0.9 7.2 4 2 3 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EPE33632.1 - 9.2e-20 69.7 33.2 0.00078 19.0 0.1 7.6 7 0 0 7 7 7 6 FG-GAP repeat Lipase_GDSL PF00657.17 EPE33632.1 - 3.1e-13 50.0 0.1 5.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EPE33632.1 - 1.7e-12 47.8 0.0 3.7e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 EPE33632.1 - 2e-09 37.1 18.5 0.21 11.0 0.0 6.9 3 3 4 7 7 7 5 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 EPE33632.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BBS2_C PF14782.1 EPE33632.1 - 0.022 13.3 1.2 11 4.4 0.1 3.8 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, C-terminal NmrA PF05368.8 EPE33634.1 - 3e-06 26.6 0.0 1.2e-05 24.6 0.0 1.7 2 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EPE33634.1 - 2.5e-05 24.3 0.0 0.00018 21.5 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Arm PF00514.18 EPE33637.1 - 1.3e-94 307.1 16.1 8.3e-14 50.8 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPE33637.1 - 2.3e-26 91.8 2.1 1.9e-10 40.8 0.0 5.9 1 1 7 8 8 8 7 HEAT repeats IBB PF01749.15 EPE33637.1 - 2.9e-22 78.6 0.8 5.9e-22 77.6 0.6 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EPE33637.1 - 8.3e-21 73.8 12.8 3.5e-09 36.8 0.0 6.3 5 1 2 7 7 7 4 HEAT-like repeat HEAT PF02985.17 EPE33637.1 - 3.8e-20 70.0 1.2 1.1e-05 25.1 0.0 7.2 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.8 EPE33637.1 - 1.9e-11 43.5 0.0 0.00012 21.3 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EPE33637.1 - 1.8e-06 26.5 0.0 0.00023 19.6 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 EPE33637.1 - 4e-05 23.5 0.1 0.37 10.7 0.0 4.5 3 1 2 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EPE33637.1 - 0.0011 17.3 0.1 0.14 10.3 0.0 2.9 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.1 EPE33637.1 - 0.015 15.1 4.7 1.4 8.9 0.0 4.5 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.12 EPE33637.1 - 0.029 13.9 0.0 33 4.1 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain HEAT_PBS PF03130.11 EPE33637.1 - 0.034 14.6 6.6 1.4 9.6 0.2 4.8 5 1 0 5 5 5 0 PBS lyase HEAT-like repeat Mo25 PF08569.6 EPE33637.1 - 0.14 11.1 0.0 2.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Mo25-like ETX_MTX2 PF03318.8 EPE33638.1 - 0.00055 19.5 22.6 0.00063 19.3 14.0 2.3 2 1 0 2 2 2 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 vWF_A PF12450.3 EPE33638.1 - 0.037 13.7 0.1 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor DIOX_N PF14226.1 EPE33641.1 - 8e-23 81.1 0.0 1.2e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPE33641.1 - 6.4e-14 52.0 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.3 EPE33642.1 - 4.8e-67 225.4 0.0 6.9e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EPE33642.1 - 7.6e-24 83.8 0.0 2.1e-23 82.4 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EPE33642.1 - 2.9e-05 24.0 0.0 7.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EPE33642.1 - 0.00085 19.5 0.0 0.0028 17.8 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain TruB_N PF01509.13 EPE33643.1 - 1.5e-42 145.3 0.0 4.4e-42 143.7 0.0 1.7 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) ATP-synt_G PF04718.10 EPE33643.1 - 7.8 7.2 6.4 0.94 10.1 0.5 2.3 3 1 0 3 3 3 0 Mitochondrial ATP synthase g subunit zf-MYND PF01753.13 EPE33644.1 - 5.8e-07 29.2 18.9 1.7e-06 27.7 13.1 1.9 1 0 0 1 1 1 1 MYND finger Zip PF02535.17 EPE33644.1 - 0.73 8.7 4.0 1.2 8.0 2.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Mito_fiss_reg PF05308.6 EPE33645.1 - 0.013 14.9 1.1 0.018 14.3 0.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PspB PF06667.7 EPE33645.1 - 2.2 8.2 4.7 14 5.6 0.4 2.5 1 1 1 2 2 2 0 Phage shock protein B F-box PF00646.28 EPE33646.1 - 5.6e-06 25.8 2.4 1.7e-05 24.3 1.7 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE33646.1 - 0.00023 20.8 1.5 0.00065 19.3 1.0 1.8 1 0 0 1 1 1 1 F-box-like FixQ PF05545.6 EPE33647.1 - 0.00046 19.7 0.2 0.0007 19.1 0.1 1.3 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ CcmD PF04995.9 EPE33647.1 - 0.00097 18.8 0.3 0.0015 18.1 0.2 1.3 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) DUF3377 PF11857.3 EPE33647.1 - 0.0035 16.9 0.0 0.0044 16.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) ASFV_J13L PF05568.6 EPE33647.1 - 0.008 15.7 0.0 0.0094 15.5 0.0 1.1 1 0 0 1 1 1 1 African swine fever virus J13L protein Adeno_E3_CR2 PF02439.10 EPE33647.1 - 0.014 14.8 1.3 0.014 14.8 0.9 1.5 1 1 1 2 2 2 0 Adenovirus E3 region protein CR2 DUF4448 PF14610.1 EPE33647.1 - 0.016 14.7 0.1 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2681 PF10883.3 EPE33647.1 - 0.058 13.6 0.1 0.072 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) EphA2_TM PF14575.1 EPE33647.1 - 0.074 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MFS_Mycoplasma PF07672.8 EPE33647.1 - 0.077 12.1 0.0 0.082 12.0 0.0 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF2500 PF10694.4 EPE33647.1 - 0.086 12.8 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) EzrA PF06160.7 EPE33647.1 - 0.12 10.5 0.0 0.14 10.3 0.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA BatD PF13584.1 EPE33647.1 - 0.12 10.8 0.0 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance TrbC PF04956.8 EPE33648.1 - 0.0056 16.6 7.9 0.025 14.5 0.2 3.3 3 0 0 3 3 3 1 TrbC/VIRB2 family MARVEL PF01284.18 EPE33648.1 - 0.016 15.0 2.7 0.016 15.0 1.9 3.1 1 1 2 3 3 3 0 Membrane-associating domain PsbN PF02468.10 EPE33648.1 - 0.025 14.1 0.5 0.15 11.6 0.4 2.3 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) CopD PF05425.8 EPE33648.1 - 0.28 11.4 10.3 0.28 11.4 2.1 2.8 2 1 0 2 2 2 0 Copper resistance protein D COX4_pro_2 PF07835.7 EPE33648.1 - 4.4 7.3 7.6 1.9 8.5 0.3 3.4 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV zf-C2H2_4 PF13894.1 EPE33649.1 - 1.7e-05 24.7 19.4 0.0091 16.2 1.4 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE33649.1 - 0.0015 18.7 16.8 0.011 16.0 1.8 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type DUF2964 PF11177.3 EPE33650.1 - 0.15 11.9 0.2 0.15 11.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) HET PF06985.6 EPE33651.1 - 3.5e-22 79.0 0.1 7.3e-22 78.0 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EPE33651.1 - 0.00013 22.2 0.0 0.11 12.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Thioredoxin PF00085.15 EPE33652.1 - 7.2e-26 89.8 0.4 1.9e-25 88.5 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin PITH PF06201.8 EPE33652.1 - 5.2e-10 39.2 0.1 1.1e-09 38.2 0.1 1.5 1 1 0 1 1 1 1 PITH domain Thioredoxin_8 PF13905.1 EPE33652.1 - 4.1e-05 23.6 0.0 8.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EPE33652.1 - 0.00022 21.3 0.2 0.00098 19.3 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EPE33652.1 - 0.00039 20.3 0.0 0.00086 19.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EPE33652.1 - 0.0065 16.1 0.1 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EPE33652.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.5 EPE33652.1 - 0.021 14.3 0.1 0.047 13.2 0.1 1.6 1 0 0 1 1 1 0 Redoxin BMF PF15185.1 EPE33652.1 - 0.095 11.9 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis Tet_JBP PF12851.2 EPE33653.1 - 1.4e-06 27.7 0.0 2.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily RAI1 PF08652.6 EPE33653.1 - 0.15 11.8 0.9 0.39 10.5 0.6 1.6 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease TIM21 PF08294.6 EPE33654.1 - 7e-44 148.9 0.0 8.9e-44 148.6 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EPE33654.1 - 5.4e-05 22.6 0.0 0.00012 21.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DBR1 PF05011.8 EPE33654.1 - 0.099 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain ArfGap PF01412.13 EPE33655.1 - 4.8e-36 123.0 0.6 8.4e-36 122.3 0.1 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Choline_transpo PF04515.7 EPE33656.1 - 1.2e-99 333.2 29.4 1.2e-99 333.2 20.4 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.8 EPE33656.1 - 0.065 13.2 2.2 0.15 12.0 1.5 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Thioredox_DsbH PF03190.10 EPE33657.1 - 0.091 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 TFIID-18kDa PF02269.11 EPE33662.1 - 6.6e-29 99.5 2.6 2e-28 98.0 0.2 2.5 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.13 EPE33662.1 - 0.12 11.4 0.5 0.19 10.8 0.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TPR_11 PF13414.1 EPE33663.1 - 9.2e-11 41.2 4.6 4.5e-06 26.2 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EPE33663.1 - 2.5e-09 36.3 3.3 0.0043 16.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPE33663.1 - 2.2e-06 27.1 1.9 0.033 14.0 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EPE33663.1 - 9.3e-05 22.4 0.7 0.00019 21.5 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EPE33663.1 - 0.026 14.7 0.3 0.14 12.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPE33663.1 - 0.051 13.9 0.4 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPE33663.1 - 0.051 13.3 0.5 0.92 9.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_topoisoIV PF00521.15 EPE33665.1 - 3.2e-119 398.5 0.0 5e-119 397.9 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EPE33665.1 - 1.7e-32 112.0 2.1 4.2e-32 110.7 1.4 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EPE33665.1 - 8.3e-12 44.9 0.0 2.8e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EPE33665.1 - 1.3e-10 40.9 0.0 3.6e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3785 PF12653.2 EPE33665.1 - 0.6 9.9 8.0 1.3 8.9 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) RabGAP-TBC PF00566.13 EPE33666.1 - 2.2e-48 164.5 0.7 4.6e-48 163.5 0.0 2.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain HALZ PF02183.13 EPE33666.1 - 0.3 10.8 4.4 6.2 6.6 0.4 3.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1664 PF07889.7 EPE33666.1 - 9.4 6.0 12.0 0.79 9.5 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ank_5 PF13857.1 EPE33667.1 - 4.3e-11 42.6 0.2 3.7e-06 27.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPE33667.1 - 2.9e-10 40.3 0.0 8.5e-09 35.6 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) NACHT PF05729.7 EPE33667.1 - 7.4e-09 35.4 0.2 1.9e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.1 EPE33667.1 - 1.5e-08 34.9 0.3 0.0047 17.4 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EPE33667.1 - 1.3e-05 24.7 0.1 0.45 10.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EPE33667.1 - 0.00015 21.6 0.2 2.5 8.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat AAA_22 PF13401.1 EPE33667.1 - 0.00022 21.3 0.0 0.00096 19.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EPE33667.1 - 0.068 13.3 0.0 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) B PF02216.11 EPE33667.1 - 0.14 11.8 0.1 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 B domain SET PF00856.23 EPE33668.1 - 7.8e-08 32.7 0.3 1.6e-06 28.5 0.2 2.8 2 1 0 2 2 2 1 SET domain APH PF01636.18 EPE33670.1 - 6.4e-10 39.1 0.0 1.2e-09 38.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE33670.1 - 0.00097 18.7 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPE33670.1 - 0.016 14.3 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_Tyr PF07714.12 EPE33670.1 - 0.023 13.7 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 EPE33670.1 - 0.034 13.4 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Abhydrolase_2 PF02230.11 EPE33671.1 - 3.9e-19 68.9 0.1 1.3e-08 34.5 0.0 2.4 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EPE33671.1 - 7.1e-09 35.8 0.0 8.7e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE33671.1 - 4.3e-07 29.8 0.0 6.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE33671.1 - 1.1e-06 28.0 0.0 1.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.9 EPE33671.1 - 0.0006 19.1 0.0 0.018 14.2 0.0 2.0 2 0 0 2 2 2 1 Secretory lipase DLH PF01738.13 EPE33671.1 - 0.0024 17.2 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 EPE33671.1 - 0.0027 17.1 0.0 0.0047 16.3 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EPE33671.1 - 0.029 13.9 0.1 0.11 12.0 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ribonucleas_3_3 PF14622.1 EPE33674.1 - 3.7e-05 23.7 0.0 0.0054 16.6 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 EPE33674.1 - 9.5e-05 22.9 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EPE33674.1 - 0.054 13.9 0.0 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 Ribonuclease III domain La PF05383.12 EPE33676.1 - 3.1e-14 52.5 0.0 6.3e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 EPE33676.1 - 0.03 14.3 0.3 0.24 11.4 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1501 PF07394.7 EPE33678.1 - 0.74 8.5 5.2 1.3 7.7 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) CAP_N PF01213.14 EPE33679.1 - 8.6e-90 301.1 2.4 8.6e-90 301.1 1.6 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EPE33679.1 - 5.6e-59 198.0 4.5 7.7e-59 197.5 3.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EPE33679.1 - 0.0011 18.3 3.3 0.0029 16.9 2.3 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C PfkB PF00294.19 EPE33680.1 - 1.2e-14 54.1 0.0 1.6e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.18 EPE33681.1 - 1.5e-129 431.5 1.4 2.2e-129 431.0 0.9 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPE33681.1 - 6.4e-18 65.4 0.2 4.9e-17 62.5 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPE33681.1 - 8.1e-08 31.6 0.1 1.2e-06 27.8 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EPE33681.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPE33681.1 - 0.0087 15.5 0.0 0.035 13.5 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Carb_bind PF10645.4 EPE33683.1 - 4.5e-16 58.3 21.5 1.9e-09 37.1 2.8 3.3 3 1 1 4 4 4 2 Carbohydrate binding NYD-SP12_N PF15015.1 EPE33683.1 - 0.13 10.4 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal LDB19 PF13002.2 EPE33685.1 - 3.1e-40 137.7 0.9 1e-39 136.0 0.6 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.24 EPE33685.1 - 1.2e-06 28.3 0.0 3.2e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.6 EPE33685.1 - 0.00026 20.4 0.0 0.00043 19.6 0.0 1.3 1 0 0 1 1 1 1 SpoOM protein SATase_N PF06426.9 EPE33687.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal 7tm_2 PF00002.19 EPE33687.1 - 0.11 11.6 3.4 0.14 11.2 1.8 1.6 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) zf-PARP PF00645.13 EPE33689.1 - 0.18 12.0 2.7 0.41 10.9 1.9 1.5 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF2823 PF11034.3 EPE33691.1 - 0.095 12.8 1.5 0.14 12.2 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2823) Elongin_A PF06881.6 EPE33691.1 - 0.12 12.7 1.4 0.16 12.3 0.7 1.4 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Aldedh PF00171.17 EPE33692.1 - 8.2e-161 535.4 0.4 9.6e-161 535.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.1 EPE33693.1 - 8.1e-27 94.5 0.1 9.6e-27 94.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE33693.1 - 1.4e-26 93.4 0.4 1.9e-26 92.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE33693.1 - 3.2e-14 53.0 0.3 5.2e-14 52.3 0.2 1.3 1 0 0 1 1 1 1 KR domain FdsD PF11390.3 EPE33693.1 - 0.11 12.5 0.4 0.26 11.4 0.3 1.6 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Fungal_trans PF04082.13 EPE33694.1 - 2.6e-21 75.6 0.1 7.3e-21 74.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE33694.1 - 6e-09 35.6 10.1 1.1e-08 34.8 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EPE33695.1 - 6e-83 278.8 29.9 7e-83 278.6 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE33695.1 - 1.5e-12 46.9 64.9 1.7e-11 43.4 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 EPE33696.1 - 2.7e-24 86.3 0.0 5.5e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE33696.1 - 5e-12 45.6 0.0 1.7e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EPE33696.1 - 3.4e-11 42.0 1.0 3.4e-10 38.7 0.3 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPE33696.1 - 5.6e-08 32.0 0.3 9.7e-05 21.4 0.0 3.4 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPE33696.1 - 2.4e-06 27.5 0.0 8.7e-05 22.4 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE33696.1 - 2e-05 24.3 0.0 0.00077 19.2 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EPE33696.1 - 0.0036 17.3 0.1 36 4.4 0.0 3.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EPE33696.1 - 0.023 13.7 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EPE33696.1 - 0.064 12.1 0.0 2.4 6.9 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.20 EPE33697.1 - 3.1e-23 82.5 3.0 7.7e-23 81.2 2.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE33697.1 - 3.3e-14 53.2 0.0 4.7e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE33697.1 - 3.7e-09 36.4 2.6 2.1e-08 34.0 1.8 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPE33697.1 - 9.2e-05 21.4 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Transketolase_N PF00456.16 EPE33698.1 - 3.7e-107 357.9 0.1 7.1e-107 357.0 0.1 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EPE33698.1 - 1e-34 119.5 0.0 2.5e-34 118.3 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EPE33698.1 - 9.8e-10 38.4 0.0 2.2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EPE33698.1 - 8.6e-08 31.4 0.2 1.5e-06 27.3 0.1 2.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EPE33698.1 - 0.0013 18.3 0.8 0.006 16.1 0.6 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EPE33698.1 - 0.058 12.1 0.2 0.12 11.1 0.1 1.5 1 0 0 1 1 1 0 Dehydrogenase E1 component DUF3343 PF11823.3 EPE33698.1 - 0.07 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Epimerase PF01370.16 EPE33699.1 - 4.5e-12 45.9 0.0 2.7e-05 23.7 0.0 2.1 1 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE33699.1 - 2.1e-09 36.4 0.0 2.5e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPE33699.1 - 1.6e-05 23.9 0.0 5.9e-05 22.1 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EPE33699.1 - 4.9e-05 23.4 0.0 7.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE33699.1 - 0.00016 21.0 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family LysR_substrate PF03466.15 EPE33699.1 - 0.0088 15.1 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 LysR substrate binding domain Semialdhyde_dh PF01118.19 EPE33699.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Cyclase PF04199.8 EPE33700.1 - 5.3e-16 58.7 0.0 8.2e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase p450 PF00067.17 EPE33701.1 - 2.6e-41 141.6 0.0 3.2e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Scytalone_dh PF02982.9 EPE33702.1 - 9.5e-66 220.2 0.6 1.1e-65 220.0 0.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EPE33702.1 - 2.9e-05 23.9 0.2 4.3e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain adh_short PF00106.20 EPE33703.1 - 7.3e-30 104.0 0.1 1e-29 103.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE33703.1 - 1.3e-28 100.3 0.0 1.6e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE33703.1 - 5.5e-13 48.9 0.1 7.9e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE33703.1 - 0.00025 20.5 0.1 0.00084 18.8 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.21 EPE33704.1 - 1.2e-80 270.6 0.0 2.4e-80 269.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPE33704.1 - 3.2e-53 181.1 0.0 1.3e-52 179.1 0.1 1.9 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EPE33704.1 - 5e-32 110.2 0.1 2e-31 108.3 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EPE33704.1 - 2.4e-31 109.7 0.0 6.8e-31 108.2 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.1 EPE33704.1 - 1.1e-21 77.2 0.0 5.3e-21 75.0 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.20 EPE33704.1 - 7.9e-11 42.0 1.0 1.4e-09 38.0 0.3 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EPE33704.1 - 5.3e-07 29.4 0.0 0.015 15.0 0.0 2.9 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE33704.1 - 8.3e-06 25.8 1.4 0.00011 22.1 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 EPE33704.1 - 5.1e-05 22.3 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain APH PF01636.18 EPE33705.1 - 9e-20 71.4 0.0 1.2e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE33705.1 - 1.2e-05 25.0 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EPE33705.1 - 7.7e-05 21.9 0.0 0.082 12.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.17 EPE33705.1 - 0.00014 21.2 0.1 0.028 13.7 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Fructosamin_kin PF03881.9 EPE33705.1 - 0.0015 17.5 0.0 0.14 11.1 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase Pkinase_Tyr PF07714.12 EPE33705.1 - 0.051 12.6 0.0 0.22 10.5 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase DUF932 PF06067.6 EPE33705.1 - 0.055 12.7 0.1 0.097 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF932) PLA2_B PF01735.13 EPE33705.1 - 0.059 11.5 0.0 0.087 10.9 0.0 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Kdo PF06293.9 EPE33705.1 - 0.059 12.4 0.1 4.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.6 EPE33705.1 - 0.07 11.7 0.2 1.6 7.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1679) TAF4 PF05236.9 EPE33708.1 - 3.1e-17 62.7 0.0 9.5e-15 54.5 0.0 2.8 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CDK2AP PF09806.4 EPE33708.1 - 2.7 8.1 8.7 0.14 12.4 0.6 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein CPSF73-100_C PF11718.3 EPE33709.1 - 2.1e-75 252.7 0.0 3.3e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EPE33709.1 - 1.7e-31 108.8 0.0 3.4e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EPE33709.1 - 1.7e-14 53.9 1.1 3.2e-14 53.0 0.8 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPE33709.1 - 4.1e-12 46.0 0.7 7.3e-12 45.2 0.5 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EPE33709.1 - 1.1e-07 31.4 0.5 2.2e-07 30.5 0.1 1.8 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EPE33709.1 - 1.8e-06 27.7 0.1 4.3e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DnaJ PF00226.26 EPE33710.1 - 1.4e-16 59.9 0.7 1.4e-16 59.9 0.5 2.2 2 0 0 2 2 2 1 DnaJ domain DUF3740 PF12548.3 EPE33711.1 - 0.00024 21.3 0.2 0.00045 20.5 0.2 1.5 1 0 0 1 1 1 1 Sulfatase protein Mei4 PF13971.1 EPE33711.1 - 0.0022 17.0 1.9 0.0038 16.2 0.4 2.1 2 1 0 2 2 2 1 Meiosis-specific protein Mei4 DUF3542 PF12061.3 EPE33711.1 - 0.086 11.7 0.6 0.14 11.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3542) DivIC PF04977.10 EPE33711.1 - 0.11 11.9 1.6 18 4.8 1.2 2.5 2 0 0 2 2 2 0 Septum formation initiator 2OG-FeII_Oxy PF03171.15 EPE33712.1 - 4.3e-21 75.0 0.0 7.2e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EPE33712.1 - 4.7e-19 69.0 0.0 1.5e-18 67.4 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Amidohydro_2 PF04909.9 EPE33713.1 - 1.7e-46 158.9 0.0 2e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Asparaginase PF00710.15 EPE33713.1 - 0.043 12.6 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Asparaginase CCDC144C PF14915.1 EPE33716.1 - 0.017 14.0 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Seryl_tRNA_N PF02403.17 EPE33717.1 - 0.00034 20.5 11.3 0.00049 20.0 7.9 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Tektin PF03148.9 EPE33717.1 - 0.0018 16.8 3.4 0.0022 16.5 2.4 1.1 1 0 0 1 1 1 1 Tektin family Mnd1 PF03962.10 EPE33717.1 - 0.0074 15.9 7.6 0.009 15.6 5.3 1.1 1 0 0 1 1 1 1 Mnd1 family Transposase_22 PF02994.9 EPE33717.1 - 0.01 14.3 9.5 0.011 14.2 6.6 1.0 1 0 0 1 1 1 0 L1 transposable element DUF4200 PF13863.1 EPE33717.1 - 0.014 15.3 16.9 0.029 14.3 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF342 PF03961.8 EPE33717.1 - 0.014 13.7 5.8 0.016 13.6 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EPE33717.1 - 0.016 13.0 7.6 0.017 12.9 5.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HalX PF08663.5 EPE33717.1 - 0.016 15.1 2.8 1 9.4 0.1 2.1 2 0 0 2 2 2 0 HalX domain DUF677 PF05055.7 EPE33717.1 - 0.019 13.6 4.8 0.021 13.4 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DivIC PF04977.10 EPE33717.1 - 0.025 14.0 9.6 0.16 11.5 0.4 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF2439 PF10382.4 EPE33717.1 - 0.028 14.6 2.4 0.038 14.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) DUF2450 PF10475.4 EPE33717.1 - 0.038 12.8 4.4 0.045 12.6 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) DivIVA PF05103.8 EPE33717.1 - 0.063 13.3 8.2 0.22 11.5 0.7 2.1 1 1 0 2 2 2 0 DivIVA protein Kinetocho_Slk19 PF12709.2 EPE33717.1 - 0.065 13.3 8.1 0.48 10.5 0.9 2.1 2 0 0 2 2 2 0 Central kinetochore-associated TMF_TATA_bd PF12325.3 EPE33717.1 - 0.075 12.7 11.8 0.14 11.8 8.2 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 EPE33717.1 - 0.11 10.9 5.4 0.12 10.7 3.8 1.1 1 0 0 1 1 1 0 AAA domain Phasin PF05597.6 EPE33717.1 - 0.12 12.1 7.2 1.1 9.0 5.0 1.9 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Relaxase PF03432.9 EPE33717.1 - 0.14 11.5 4.1 0.16 11.3 2.9 1.0 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain PspA_IM30 PF04012.7 EPE33717.1 - 0.15 11.4 6.6 0.18 11.1 4.5 1.1 1 0 0 1 1 1 0 PspA/IM30 family NPV_P10 PF05531.7 EPE33717.1 - 0.16 12.2 1.6 2.6 8.3 1.1 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 EPE33717.1 - 0.17 11.4 9.9 1.8 8.0 2.1 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 EPE33717.1 - 0.17 11.7 4.8 0.27 11.0 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) COG5 PF10392.4 EPE33717.1 - 0.17 11.8 2.6 0.23 11.4 1.8 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF1192 PF06698.6 EPE33717.1 - 0.18 11.6 13.5 1.2 9.0 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF4201 PF13870.1 EPE33717.1 - 0.22 10.9 9.6 0.28 10.5 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Phage_GP20 PF06810.6 EPE33717.1 - 0.22 10.9 8.6 0.66 9.3 5.6 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 Pox_A_type_inc PF04508.7 EPE33717.1 - 0.24 11.2 11.3 0.15 11.9 1.5 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat 5_nucleotid PF05761.9 EPE33717.1 - 0.31 9.5 3.9 0.35 9.3 2.7 1.0 1 0 0 1 1 1 0 5' nucleotidase family Syntaxin PF00804.20 EPE33717.1 - 0.31 11.2 6.5 0.82 9.8 4.2 1.8 1 1 0 1 1 1 0 Syntaxin SlyX PF04102.7 EPE33717.1 - 0.31 11.4 3.5 2.5 8.5 0.3 2.1 1 1 1 2 2 2 0 SlyX FemAB PF02388.11 EPE33717.1 - 0.36 9.4 2.9 0.46 9.1 2.0 1.1 1 0 0 1 1 1 0 FemAB family HALZ PF02183.13 EPE33717.1 - 0.37 10.5 9.1 2.4 7.9 0.6 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper Fib_alpha PF08702.5 EPE33717.1 - 0.43 10.7 3.3 0.82 9.7 2.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1465 PF07323.7 EPE33717.1 - 0.47 10.0 2.7 0.56 9.7 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) ATG16 PF08614.6 EPE33717.1 - 0.51 10.1 10.4 1.3 8.7 7.2 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Bacillus_HBL PF05791.6 EPE33717.1 - 0.52 9.6 3.2 0.65 9.3 2.2 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TPR_MLP1_2 PF07926.7 EPE33717.1 - 0.54 9.9 7.5 1.1 9.0 5.2 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1003 PF06210.6 EPE33717.1 - 0.56 10.1 5.5 1.3 8.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) Spc24 PF08286.6 EPE33717.1 - 0.64 9.7 7.9 0.55 9.9 0.6 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.4 EPE33717.1 - 0.67 8.8 7.4 0.81 8.5 5.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HOOK PF05622.7 EPE33717.1 - 0.69 7.6 10.7 1.1 7.0 1.0 1.9 1 1 1 2 2 2 0 HOOK protein FlaC_arch PF05377.6 EPE33717.1 - 0.82 9.6 8.3 0.58 10.0 1.4 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) FlxA PF14282.1 EPE33717.1 - 1 9.3 4.1 3.4 7.6 2.8 1.7 1 1 0 1 1 1 0 FlxA-like protein Spc7 PF08317.6 EPE33717.1 - 1.1 7.8 8.8 1.5 7.4 6.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 EPE33717.1 - 1.2 8.1 8.4 1.4 7.8 5.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Cauli_AT PF03233.8 EPE33717.1 - 1.3 8.6 7.2 1.7 8.3 5.0 1.1 1 0 0 1 1 1 0 Aphid transmission protein Cep57_CLD_2 PF14197.1 EPE33717.1 - 1.5 8.8 12.3 2 8.3 1.0 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 EAP30 PF04157.11 EPE33717.1 - 1.5 7.9 5.5 5.1 6.2 3.9 1.7 1 1 0 1 1 1 0 EAP30/Vps36 family IncA PF04156.9 EPE33717.1 - 1.5 8.3 10.8 3.6 7.1 7.5 1.6 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 EPE33717.1 - 1.6 8.6 15.7 10 5.9 10.9 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ax_dynein_light PF10211.4 EPE33717.1 - 1.9 8.2 13.1 63 3.3 8.9 2.0 1 1 0 1 1 1 0 Axonemal dynein light chain DUF4140 PF13600.1 EPE33717.1 - 2 8.9 8.2 5.9 7.4 0.7 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.16 EPE33717.1 - 2 8.4 12.1 1.3 9.0 1.1 2.4 1 1 1 2 2 2 0 bZIP transcription factor Fmp27_WPPW PF10359.4 EPE33717.1 - 2.2 6.5 7.4 1.6 7.0 1.4 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF904 PF06005.7 EPE33717.1 - 2.3 8.5 12.5 2.9 8.2 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Wbp11 PF09429.5 EPE33717.1 - 3 7.9 14.0 11 6.1 4.5 2.3 1 1 1 2 2 2 0 WW domain binding protein 11 DUF724 PF05266.9 EPE33717.1 - 3 7.4 9.4 4 7.0 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ENT PF03735.9 EPE33717.1 - 3.1 7.5 5.3 4 7.2 0.4 2.1 1 1 1 2 2 2 0 ENT domain DUF2681 PF10883.3 EPE33717.1 - 3.2 8.0 7.9 9.8 6.4 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF241 PF03087.9 EPE33717.1 - 3.4 7.0 11.0 5.8 6.3 7.6 1.3 1 1 0 1 1 1 0 Arabidopsis protein of unknown function DUF2031 PF09592.5 EPE33717.1 - 3.9 6.5 9.0 4.7 6.3 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) AKNA PF12443.3 EPE33717.1 - 7 6.7 6.5 5.8 6.9 0.2 2.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor COG2 PF06148.6 EPE33717.1 - 7.6 6.4 7.1 30 4.4 4.4 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ORF6C PF10552.4 EPE33717.1 - 9.1 6.0 8.0 8.4 6.1 0.6 2.1 1 1 1 2 2 2 0 ORF6C domain AbiH PF14253.1 EPE33718.1 - 0.031 13.8 3.7 0.037 13.6 2.6 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH FadA PF09403.5 EPE33718.1 - 0.075 13.0 11.4 0.025 14.5 4.6 1.9 1 1 1 2 2 2 0 Adhesion protein FadA IncA PF04156.9 EPE33718.1 - 0.15 11.6 6.7 0.16 11.5 4.6 1.2 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 EPE33718.1 - 0.66 9.1 9.8 0.9 8.6 5.8 1.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ABC2_membrane_4 PF12730.2 EPE33719.1 - 0.046 12.8 15.6 0.013 14.6 2.1 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF3397 PF11877.3 EPE33719.1 - 3.2 7.7 12.7 0.77 9.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3397) DUF1308 PF07000.6 EPE33720.1 - 1.8e-72 244.0 1.4 2.2e-72 243.6 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) WD40 PF00400.27 EPE33721.1 - 3.9e-19 67.7 1.5 2.3e-08 33.5 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EPE33721.1 - 0.016 14.9 0.0 9.4 5.8 0.0 4.1 4 1 1 5 5 5 0 Eukaryotic translation initiation factor eIF2A SnoaL_4 PF13577.1 EPE33721.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Mito_carr PF00153.22 EPE33722.1 - 1.3e-59 197.9 4.1 2.7e-20 71.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2392 PF10288.4 EPE33723.1 - 2.4e-28 98.5 0.0 4.4e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DZR PF12773.2 EPE33723.1 - 0.0017 18.1 5.3 0.02 14.6 1.1 2.4 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.1 EPE33723.1 - 1.8 8.1 5.0 0.62 9.6 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon domain Lung_7-TM_R PF06814.8 EPE33724.1 - 4.1e-74 249.2 12.2 4.9e-74 248.9 8.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor EmrE PF13536.1 EPE33724.1 - 0.034 14.3 1.6 0.034 14.3 1.1 3.1 1 1 2 3 3 3 0 Multidrug resistance efflux transporter PrgI PF12666.2 EPE33724.1 - 0.7 10.0 17.5 7.3 6.8 1.4 3.6 3 1 0 3 3 3 0 PrgI family protein GCV_T PF01571.16 EPE33725.1 - 6.4e-17 61.6 0.0 1.3e-15 57.3 0.0 2.0 1 1 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EPE33725.1 - 0.0026 17.7 0.2 0.0047 16.9 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Nramp PF01566.13 EPE33726.1 - 1.3e-88 297.2 18.5 1.3e-88 297.2 12.8 1.6 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein DCP2 PF05026.8 EPE33727.1 - 7.4e-36 121.9 1.0 1.4e-35 120.9 0.7 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EPE33727.1 - 4.7e-16 58.6 0.0 9.2e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.1 EPE33728.1 - 1.5e-33 114.8 0.3 2e-33 114.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Ribonuc_red_sm PF00268.16 EPE33729.1 - 2.2e-120 400.8 3.6 2.7e-120 400.6 2.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.7 EPE33730.1 - 2.7e-29 100.7 0.5 3.8e-29 100.2 0.3 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Mucin PF01456.12 EPE33732.1 - 0.072 12.8 26.8 0.026 14.2 11.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein GFO_IDH_MocA PF01408.17 EPE33734.1 - 1.7e-14 54.3 0.0 2.9e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RhoGAP PF00620.22 EPE33735.1 - 3.7e-35 120.7 0.0 1.4e-34 118.8 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EPE33735.1 - 4.3e-34 116.3 37.4 3.8e-13 49.2 5.0 5.2 5 0 0 5 5 5 4 LIM domain Het-C PF07217.6 EPE33736.1 - 8.7e-286 948.9 0.0 1e-285 948.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Pkinase PF00069.20 EPE33739.1 - 4.7e-61 206.1 0.0 4.6e-40 137.3 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE33739.1 - 6.6e-26 90.9 0.0 2.7e-20 72.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EPE33739.1 - 5.2e-14 52.1 0.1 1e-13 51.2 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EPE33739.1 - 7.4e-08 31.6 0.0 2.7e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPE33739.1 - 1.3e-05 25.0 0.0 0.0053 16.5 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS_9 PF13426.1 EPE33739.1 - 0.0039 17.5 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain Kdo PF06293.9 EPE33739.1 - 0.023 13.7 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EPE33739.1 - 0.07 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DnaJ PF00226.26 EPE33741.1 - 7.6e-19 67.2 1.3 7.6e-19 67.2 0.9 1.9 2 0 0 2 2 2 1 DnaJ domain IBR PF01485.16 EPE33741.1 - 1.8 8.4 12.1 0.13 12.1 4.5 2.1 2 0 0 2 2 2 0 IBR domain DUF4094 PF13334.1 EPE33741.1 - 4.4 7.7 7.6 2.1 8.7 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) MFS_1 PF07690.11 EPE33742.1 - 2.8e-36 124.9 63.1 4.4e-36 124.3 40.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily RTA1 PF04479.8 EPE33743.1 - 8.6e-44 149.6 8.3 8.6e-44 149.6 5.8 1.6 2 0 0 2 2 2 1 RTA1 like protein Poxvirus_B22R_C PF13168.1 EPE33743.1 - 0.079 12.2 0.1 0.63 9.2 0.0 2.0 2 0 0 2 2 2 0 Poxvirus B22R protein C-terminal MFS_1 PF07690.11 EPE33744.1 - 5.6e-48 163.4 47.2 5.6e-48 163.4 32.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPE33744.1 - 1.8e-21 75.9 8.9 1.8e-21 75.9 6.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE33744.1 - 2.7e-15 55.8 7.5 2.7e-15 55.8 5.2 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter ADH_zinc_N PF00107.21 EPE33745.1 - 3e-10 39.7 0.0 6.7e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE33745.1 - 0.00023 20.9 0.2 0.00061 19.5 0.1 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 EPE33746.1 - 2.1e-07 30.7 4.5 3.7e-07 29.9 3.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TrwC PF08751.6 EPE33746.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 TrwC relaxase AMP-binding PF00501.23 EPE33747.1 - 1.5e-80 270.6 0.1 2.3e-80 270.0 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EPE33747.1 - 5e-76 255.5 0.1 1e-75 254.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 EPE33747.1 - 1.3e-54 185.1 0.9 2.2e-54 184.3 0.6 1.3 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.16 EPE33747.1 - 1.1e-52 179.3 1.1 2.4e-52 178.2 0.8 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EPE33747.1 - 3.1e-51 173.6 0.0 3.8e-50 170.0 0.0 2.7 3 0 0 3 3 3 1 KR domain PS-DH PF14765.1 EPE33747.1 - 1.2e-43 149.4 0.0 2.3e-43 148.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EPE33747.1 - 2.6e-43 147.8 0.2 1.9e-40 138.5 0.0 3.4 4 0 0 4 4 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EPE33747.1 - 2.4e-33 115.1 0.0 3e-31 108.2 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EPE33747.1 - 2.2e-31 108.1 0.1 1.2e-30 105.7 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EPE33747.1 - 1.9e-18 66.7 0.0 9.9e-18 64.4 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 EPE33747.1 - 3.9e-18 65.4 2.4 5e-11 42.6 0.0 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site Epimerase PF01370.16 EPE33747.1 - 3.3e-15 56.1 0.0 1.7e-11 44.0 0.0 3.3 4 0 0 4 4 4 2 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 EPE33747.1 - 3.1e-12 46.8 0.0 1.2e-11 44.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE33747.1 - 7.5e-12 45.2 0.0 1.8e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE33747.1 - 3.8e-09 36.3 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE33747.1 - 2e-08 34.7 0.0 1.7e-06 28.5 0.0 3.3 3 0 0 3 3 3 1 Methyltransferase domain 3Beta_HSD PF01073.14 EPE33747.1 - 1.1e-07 30.8 0.0 0.00024 19.8 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family HxxPF_rpt PF13745.1 EPE33747.1 - 2.5e-07 30.8 0.0 1.2e-06 28.6 0.0 2.2 2 0 0 2 2 1 1 HxxPF-repeated domain Ubie_methyltran PF01209.13 EPE33747.1 - 1.2e-06 27.8 0.0 3.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EPE33747.1 - 1.6e-05 24.0 0.0 3.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain RmlD_sub_bind PF04321.12 EPE33747.1 - 0.00059 18.8 0.0 0.0086 14.9 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain DREV PF05219.7 EPE33747.1 - 0.028 13.2 0.0 0.06 12.2 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase adh_short PF00106.20 EPE33749.1 - 2e-21 76.6 1.1 2.7e-21 76.2 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE33749.1 - 1.6e-13 50.7 0.0 2.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE33749.1 - 3.1e-10 40.2 0.0 4.3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EPE33749.1 - 1.6e-08 33.7 0.1 2.1e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Zn_clus PF00172.13 EPE33750.1 - 0.023 14.5 1.1 0.075 12.9 0.8 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 EPE33752.1 - 5.6e-61 206.2 0.0 8.1e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE33752.1 - 3.9e-31 108.2 0.0 6.8e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EPE33752.1 - 0.0022 16.9 0.1 0.0032 16.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPE33752.1 - 0.021 13.6 0.1 5.1 5.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EPE33752.1 - 0.053 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Myb_DNA-bind_2 PF08914.6 EPE33752.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Rap1 Myb domain Trp_halogenase PF04820.9 EPE33752.1 - 0.14 10.7 0.1 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase JmjC PF02373.17 EPE33753.1 - 1.5e-39 134.7 0.2 5.4e-39 132.9 0.1 2.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EPE33753.1 - 5.8e-19 68.1 3.6 1.4e-18 66.8 2.5 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EPE33753.1 - 1.9e-18 66.3 7.8 4.5e-18 65.1 5.4 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 EPE33753.1 - 1.7e-12 46.6 0.6 3.9e-12 45.4 0.4 1.7 1 0 0 1 1 1 1 jmjN domain PhoD PF09423.5 EPE33754.1 - 1.5e-06 27.1 0.0 0.0001 21.0 0.0 2.4 2 1 0 2 2 2 2 PhoD-like phosphatase Rhomboid PF01694.17 EPE33756.1 - 2.4e-21 76.3 5.6 2.4e-21 76.3 3.9 1.6 2 0 0 2 2 2 1 Rhomboid family IU_nuc_hydro PF01156.14 EPE33760.1 - 6.3e-56 189.8 0.0 1.7e-45 155.6 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.17 EPE33761.1 - 1.1e-05 24.8 0.0 0.00016 21.1 0.0 2.1 1 1 1 2 2 2 2 LSM domain MCM PF00493.18 EPE33762.1 - 8e-142 471.9 0.4 1.1e-141 471.4 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPE33762.1 - 1.4e-19 70.7 0.4 3.2e-19 69.5 0.1 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPE33762.1 - 4.2e-06 26.0 0.0 0.00084 18.5 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPE33762.1 - 4.3e-05 23.2 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPE33762.1 - 0.00048 19.7 0.1 0.0024 17.4 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EPE33762.1 - 0.0058 16.9 0.4 0.02 15.3 0.3 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EPE33762.1 - 0.032 13.7 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2689 PF10894.3 EPE33762.1 - 0.072 12.8 0.2 8.8 6.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2689) AAA PF00004.24 EPE33762.1 - 0.1 12.8 0.4 0.56 10.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 EPE33763.1 - 1.8e-70 237.0 0.0 3.6e-70 236.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE33763.1 - 6.5e-36 123.7 0.0 1.8e-35 122.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE33763.1 - 0.00073 18.5 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPE33763.1 - 0.0032 16.5 0.2 0.0072 15.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE33763.1 - 0.0065 16.2 3.4 0.045 13.4 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Sulfotransfer_3 PF13469.1 EPE33764.1 - 0.06 14.2 0.1 0.12 13.2 0.1 1.7 1 1 0 1 1 1 0 Sulfotransferase family Carboxyl_trans PF01039.17 EPE33765.1 - 2.6e-79 266.8 0.0 3.7e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain HJURP_C PF12347.3 EPE33765.1 - 0.0075 15.8 0.1 0.021 14.4 0.1 1.6 1 0 0 1 1 1 1 Holliday junction regulator protein family C-terminal repeat DUF3600 PF12207.3 EPE33765.1 - 0.13 11.7 0.0 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) CPSase_L_D2 PF02786.12 EPE33766.1 - 4.2e-54 183.0 0.0 5.6e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EPE33766.1 - 1.8e-24 85.9 0.0 3.7e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EPE33766.1 - 6.1e-16 58.6 0.0 9.8e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPE33766.1 - 1.2e-11 43.9 0.0 1.2e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_carb_C PF02785.14 EPE33766.1 - 2.9e-10 40.0 0.0 5.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.8 EPE33766.1 - 7.2e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EPE33766.1 - 1.9e-05 24.0 0.0 3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EPE33766.1 - 2.5e-05 24.2 0.0 5.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EPE33766.1 - 0.00026 20.5 0.0 0.0013 18.2 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EPE33766.1 - 0.026 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.1 EPE33766.1 - 0.029 13.4 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp zf-RanBP PF00641.13 EPE33767.1 - 6e-20 70.0 8.9 4.4e-11 41.6 0.8 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EPE33767.1 - 5.6e-08 32.3 0.0 1.4e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE33767.1 - 2e-05 24.5 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EPE33767.1 - 5e-05 23.6 0.0 8.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-ribbon_3 PF13248.1 EPE33767.1 - 1 8.6 5.9 9.7 5.5 1.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EPE33767.1 - 1.5 8.7 8.5 1 9.2 0.9 2.5 2 0 0 2 2 2 0 Double zinc ribbon Acetyltransf_8 PF13523.1 EPE33768.1 - 0.0071 16.2 0.0 1.9 8.3 0.0 2.4 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain WD40 PF00400.27 EPE33769.1 - 4e-37 124.7 0.1 1.4e-07 31.0 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EPE33769.1 - 3e-30 103.9 0.2 9.5e-30 102.3 0.1 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex XRN_N PF03159.13 EPE33770.1 - 9.2e-102 339.4 0.1 1.5e-101 338.7 0.1 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus R3H PF01424.17 EPE33770.1 - 0.022 14.4 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 R3H domain Pmp3 PF01679.12 EPE33771.1 - 5.5e-23 80.4 7.6 6.8e-23 80.1 5.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF929 PF06053.6 EPE33771.1 - 0.08 12.0 0.3 0.17 10.9 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF929) SPC22 PF04573.7 EPE33772.1 - 3.3e-34 117.6 0.5 7.1e-25 87.2 0.1 2.0 2 0 0 2 2 2 2 Signal peptidase subunit Sel1 PF08238.7 EPE33773.1 - 0.24 12.1 2.3 0.25 12.0 0.4 2.0 2 0 0 2 2 2 0 Sel1 repeat Amino_oxidase PF01593.19 EPE33774.1 - 5e-34 118.1 0.1 1.7e-23 83.3 0.2 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPE33774.1 - 8e-06 25.8 0.0 2.1e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EPE33774.1 - 0.0008 18.5 0.2 0.0015 17.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EPE33774.1 - 0.0037 17.3 0.0 0.0061 16.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase BTB PF00651.26 EPE33775.1 - 4e-12 46.1 0.0 1e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain DnaG_DnaB_bind PF08278.6 EPE33775.1 - 0.014 15.5 0.7 0.033 14.3 0.5 1.6 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding BTB PF00651.26 EPE33776.1 - 9.1e-10 38.5 0.0 2.3e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Zn_Tnp_IS1595 PF12760.2 EPE33776.1 - 0.16 11.8 2.6 0.42 10.4 1.8 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain BTB PF00651.26 EPE33777.1 - 4.1e-10 39.6 0.2 1e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF507 PF04368.8 EPE33777.1 - 0.0074 15.9 0.2 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF507) PI31_Prot_N PF11566.3 EPE33777.1 - 0.03 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal BTB PF00651.26 EPE33778.1 - 1e-10 41.5 0.1 1.9e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain SnoaL_2 PF12680.2 EPE33779.1 - 3.8e-06 27.2 0.3 7.4e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EPE33779.1 - 0.0002 20.9 0.1 0.00048 19.7 0.1 1.7 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF946 PF06101.6 EPE33780.1 - 7.9e-51 172.6 0.1 1e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) HET PF06985.6 EPE33781.1 - 1.9e-38 131.7 1.0 2.4e-38 131.4 0.7 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2617 PF10936.3 EPE33781.1 - 0.052 13.1 0.1 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF2617 Pkinase PF00069.20 EPE33783.1 - 2.9e-70 236.4 0.0 4e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE33783.1 - 3.4e-47 160.6 0.0 7.1e-47 159.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE33783.1 - 1.5e-05 24.1 0.0 6.2e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Transglut_core PF01841.14 EPE33784.1 - 1.9e-10 40.9 0.0 7.6e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EPE33784.1 - 4.8e-09 35.5 0.0 1.2e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPE33784.1 - 3.6e-08 32.6 0.0 9.3e-08 31.3 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPE33784.1 - 3.2e-05 23.4 0.0 7.1e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3431 PF11913.3 EPE33785.1 - 0.00037 20.0 0.0 0.00091 18.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) MFS_1 PF07690.11 EPE33786.1 - 1.2e-43 149.1 46.5 1.2e-43 149.1 32.3 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE33786.1 - 5.6e-20 71.0 14.1 8.8e-20 70.4 9.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE33786.1 - 3.2e-14 52.3 9.5 3.2e-14 52.3 6.6 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.17 EPE33787.1 - 1.3e-29 103.1 0.0 2.3e-29 102.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF2561 PF10812.3 EPE33788.1 - 0.02 14.4 2.0 0.024 14.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) p450 PF00067.17 EPE33789.1 - 1.4e-29 102.9 0.0 1.8e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2474 PF10617.4 EPE33789.1 - 0.17 11.5 0.8 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) FAD_binding_4 PF01565.18 EPE33791.1 - 2.6e-19 69.0 0.9 1.3e-18 66.8 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPE33791.1 - 0.016 15.0 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like DUF1217 PF06748.7 EPE33791.1 - 0.038 14.0 0.1 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) Hex_IIIa PF02455.11 EPE33792.1 - 2.6 6.6 13.8 4.4 5.8 9.6 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Spore_II_R PF09551.5 EPE33792.1 - 3.9 7.5 20.5 4.1 7.4 5.5 2.7 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) YpjP PF14005.1 EPE33792.1 - 7.3 6.3 17.6 2.7 7.7 6.3 2.7 1 1 2 3 3 3 0 YpjP-like protein ARGLU PF15346.1 EPE33792.1 - 9.5 5.9 53.1 1.3 8.8 10.7 2.3 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 Fungal_trans_2 PF11951.3 EPE33793.1 - 6e-33 113.9 1.5 1e-32 113.2 1.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE33793.1 - 6.1e-07 29.2 6.5 1e-06 28.5 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ammonium_transp PF00909.16 EPE33794.1 - 3.8e-72 242.9 21.9 4.6e-72 242.6 15.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family AA_permease_2 PF13520.1 EPE33795.1 - 3.5e-40 137.8 55.3 4.5e-40 137.4 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE33795.1 - 6.5e-24 84.1 48.8 8.7e-24 83.6 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.13 EPE33796.1 - 7.2e-07 29.0 9.8 1.4e-06 28.0 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 EPE33797.1 - 3.6e-10 40.0 0.2 8.1e-10 38.9 0.1 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EPE33797.1 - 1.7e-09 36.7 0.0 2.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 EPE33797.1 - 4.2e-09 36.3 0.0 9.9e-09 35.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE33797.1 - 0.00043 19.9 0.0 0.0065 16.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE33797.1 - 0.021 14.0 0.0 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family ADH_zinc_N PF00107.21 EPE33798.1 - 2.9e-10 39.7 0.0 4.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE33798.1 - 0.00074 19.2 0.1 0.031 14.0 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain DUF4489 PF14879.1 EPE33798.1 - 0.016 14.8 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) MFS_1 PF07690.11 EPE33799.1 - 2.6e-43 148.0 46.3 2.6e-43 148.0 32.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE33799.1 - 2.3e-15 56.1 13.7 2.3e-15 56.1 9.5 3.2 1 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EPE33799.1 - 9.6e-15 53.7 21.9 6.1e-14 51.1 15.1 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EthD PF07110.6 EPE33801.1 - 5.9e-10 39.9 0.1 8.5e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 EthD domain DUF4188 PF13826.1 EPE33801.1 - 0.024 14.7 0.0 0.043 13.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4188) Ribul_P_3_epim PF00834.14 EPE33801.1 - 0.061 12.4 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family AMP-binding PF00501.23 EPE33802.1 - 6.7e-76 255.3 0.0 2e-75 253.8 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EPE33802.1 - 9.2e-72 241.5 0.0 1.7e-71 240.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EPE33802.1 - 9.5e-58 194.8 0.0 9.6e-56 188.2 0.0 2.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EPE33802.1 - 3.4e-51 173.4 0.1 6.4e-46 156.3 0.0 3.4 3 0 0 3 3 3 2 short chain dehydrogenase PS-DH PF14765.1 EPE33802.1 - 2.9e-48 164.5 0.0 4.4e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EPE33802.1 - 4.9e-47 160.2 0.0 7.9e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 EPE33802.1 - 1.2e-46 158.6 0.0 2.9e-46 157.4 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 EPE33802.1 - 1e-44 153.1 0.0 2.1e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EPE33802.1 - 8.7e-32 109.4 0.0 2.5e-31 107.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 EPE33802.1 - 6.5e-22 78.1 0.0 1.3e-18 67.2 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EPE33802.1 - 4.7e-17 62.0 2.5 1.3e-10 41.4 0.0 3.3 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EPE33802.1 - 4.8e-16 59.0 0.0 1.3e-15 57.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE33802.1 - 8.5e-12 45.0 0.0 2.2e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE33802.1 - 1.1e-11 44.5 0.0 3.6e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EPE33802.1 - 3.1e-11 42.4 0.0 1.5e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_11 PF08241.7 EPE33802.1 - 1.1e-10 41.8 0.0 3.2e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EPE33802.1 - 1.1e-08 35.2 0.0 3.7e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 EPE33802.1 - 1.9e-08 34.8 0.0 1.1e-07 32.4 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.1 EPE33802.1 - 6.1e-07 29.6 0.0 1.8e-05 24.8 0.0 2.8 2 0 0 2 2 2 1 NADH(P)-binding Methyltransf_25 PF13649.1 EPE33802.1 - 3.4e-06 27.3 0.0 1.4e-05 25.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE33802.1 - 1.2e-05 24.6 0.0 2.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EPE33802.1 - 4.4e-05 23.0 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Thiolase_N PF00108.18 EPE33802.1 - 0.0005 19.1 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain NmrA PF05368.8 EPE33802.1 - 0.0096 15.1 0.0 0.038 13.2 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Methyltransf_32 PF13679.1 EPE33802.1 - 0.054 13.1 0.2 0.56 9.8 0.0 2.8 4 0 0 4 4 2 0 Methyltransferase domain NodS PF05401.6 EPE33802.1 - 0.061 12.7 0.0 0.44 9.8 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EPE33802.1 - 0.067 13.2 0.0 0.21 11.5 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 EPE33802.1 - 0.096 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Glyco_hydro_42M PF08532.5 EPE33802.1 - 0.26 10.4 0.0 0.71 9.0 0.0 1.7 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Polysacc_synt_2 PF02719.10 EPE33802.1 - 0.29 9.9 0.0 1.2 7.9 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF2919 PF11143.3 EPE33802.1 - 0.37 10.6 0.1 0.92 9.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) Methyltransf_8 PF05148.10 EPE33802.1 - 0.66 9.5 0.0 1.4 8.4 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF4200 PF13863.1 EPE33803.1 - 0.072 13.0 0.9 0.1 12.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DivIC PF04977.10 EPE33803.1 - 0.11 11.9 2.0 0.16 11.4 0.1 2.0 2 1 0 2 2 2 0 Septum formation initiator DUF1640 PF07798.6 EPE33803.1 - 0.21 11.5 1.3 0.26 11.2 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) bZIP_2 PF07716.10 EPE33803.1 - 1.1 9.1 5.0 18 5.2 0.0 2.1 2 0 0 2 2 2 0 Basic region leucine zipper PH PF00169.24 EPE33804.1 - 0.0005 20.2 1.6 0.0012 18.9 1.1 1.6 1 0 0 1 1 1 1 PH domain RmlD_sub_bind PF04321.12 EPE33805.1 - 1e-53 182.0 0.0 1.4e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EPE33805.1 - 9.9e-23 80.7 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPE33805.1 - 2.9e-11 42.7 0.1 8.4e-08 31.4 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EPE33805.1 - 1.6e-10 40.1 0.0 3.7e-10 38.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPE33805.1 - 1.6e-07 31.5 0.0 2.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPE33805.1 - 1.4e-06 27.3 0.5 0.00034 19.5 0.0 2.9 1 1 0 2 2 2 2 Polysaccharide biosynthesis protein NmrA PF05368.8 EPE33805.1 - 0.0046 16.2 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EPE33805.1 - 0.041 13.8 3.4 0.37 10.6 1.3 2.6 2 1 0 2 2 2 0 short chain dehydrogenase Bd3614_N PF14442.1 EPE33806.1 - 0.064 13.2 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal FliJ PF02050.11 EPE33807.1 - 0.008 16.2 1.2 0.008 16.2 0.8 1.5 2 1 0 2 2 1 1 Flagellar FliJ protein YscO PF07321.7 EPE33807.1 - 0.052 13.3 9.7 0.15 11.8 1.9 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO DUF3567 PF12091.3 EPE33807.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) TMF_DNA_bd PF12329.3 EPE33807.1 - 0.13 12.0 4.3 4.6 7.1 0.5 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 EPE33807.1 - 0.17 10.5 4.7 0.19 10.3 3.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EPE33807.1 - 0.2 11.2 6.5 0.12 12.0 3.3 1.5 2 0 0 2 2 2 0 IncA protein Tup_N PF08581.5 EPE33807.1 - 0.6 10.3 4.2 0.8 9.9 0.2 2.2 2 0 0 2 2 2 0 Tup N-terminal COMP PF11598.3 EPE33807.1 - 0.87 9.7 5.8 4.7 7.3 4.0 2.2 1 1 0 1 1 1 0 Cartilage oligomeric matrix protein DUF1664 PF07889.7 EPE33807.1 - 0.87 9.3 3.0 3.4 7.4 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Hrs_helical PF12210.3 EPE33807.1 - 1.7 8.9 6.7 1.1 9.6 1.7 2.2 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF972 PF06156.8 EPE33807.1 - 1.7 8.9 6.3 0.92 9.8 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4201 PF13870.1 EPE33807.1 - 3.1 7.2 9.8 26 4.2 6.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) IPP-2 PF04979.9 EPE33809.1 - 7.9e-08 32.6 20.6 1.2e-05 25.5 11.8 2.5 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Fic PF02661.13 EPE33810.1 - 5.5e-16 59.0 0.0 1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family Sugar_tr PF00083.19 EPE33813.1 - 5.4e-99 331.7 24.5 6.2e-99 331.6 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE33813.1 - 4.2e-18 65.1 59.3 1.8e-16 59.8 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 EPE33813.1 - 0.0057 16.6 1.2 0.021 14.7 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2530) DUF1049 PF06305.6 EPE33813.1 - 0.27 10.7 0.1 0.27 10.7 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) AAA PF00004.24 EPE33815.1 - 3.7e-16 59.5 0.0 7.2e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE33815.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE33815.1 - 0.0018 18.4 0.4 0.14 12.2 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EPE33815.1 - 0.013 15.1 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPE33815.1 - 0.032 13.9 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Zot PF05707.7 EPE33815.1 - 0.052 13.0 0.6 1.7 8.0 0.0 2.7 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_17 PF13207.1 EPE33815.1 - 0.21 12.4 1.8 0.41 11.4 0.1 2.4 2 1 0 2 2 2 0 AAA domain PI31_Prot_C PF08577.6 EPE33819.1 - 0.09 13.4 1.7 0.11 13.1 0.3 1.9 2 0 0 2 2 2 0 PI31 proteasome regulator HDAC4_Gln PF12203.3 EPE33819.1 - 0.31 11.0 2.3 1.5 8.8 1.7 1.9 1 1 1 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 HSL_N PF06350.7 EPE33821.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus Exonuc_VII_S PF02609.11 EPE33822.1 - 0.00054 19.6 1.0 0.00077 19.1 0.3 1.5 1 1 0 1 1 1 1 Exonuclease VII small subunit SH3BP5 PF05276.9 EPE33822.1 - 0.0074 15.6 0.2 0.0083 15.4 0.2 1.0 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) OEP PF02321.13 EPE33822.1 - 0.017 14.6 1.1 0.021 14.4 0.8 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein ATP-synt_DE PF00401.15 EPE33822.1 - 0.21 11.4 3.2 0.41 10.5 2.2 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain MscS_porin PF12795.2 EPE33823.1 - 0.049 12.9 0.1 0.05 12.9 0.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF3584 PF12128.3 EPE33823.1 - 0.051 10.9 0.4 0.051 10.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_S PF02609.11 EPE33823.1 - 0.12 12.2 0.4 10 5.9 0.0 2.2 2 0 0 2 2 2 0 Exonuclease VII small subunit SNARE PF05739.14 EPE33823.1 - 0.14 11.8 0.3 15 5.3 0.0 2.1 2 0 0 2 2 2 0 SNARE domain Flagellin_N PF00669.15 EPE33823.1 - 0.15 11.8 0.1 0.17 11.6 0.0 1.0 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Sec8_exocyst PF04048.9 EPE33823.1 - 0.16 11.6 0.3 0.2 11.2 0.2 1.2 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain AP2 PF00847.15 EPE33823.1 - 0.23 11.6 2.0 0.69 10.1 0.2 2.0 2 0 0 2 2 2 0 AP2 domain ATP-synt_DE PF00401.15 EPE33823.1 - 0.4 10.5 2.5 0.25 11.2 0.2 1.8 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Pyr_redox PF00070.22 EPE33824.1 - 4.9e-15 55.7 2.8 1.2e-13 51.2 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE33824.1 - 7e-11 42.5 0.2 2.9e-05 24.2 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE33824.1 - 8.1e-09 35.6 2.9 0.0015 18.4 1.2 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE33824.1 - 0.03 12.8 1.4 2.1 6.7 0.4 2.4 1 1 1 2 2 2 0 HI0933-like protein DAO PF01266.19 EPE33824.1 - 0.041 12.7 5.5 0.21 10.4 0.4 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase K_oxygenase PF13434.1 EPE33824.1 - 0.045 12.6 0.2 0.48 9.2 0.1 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EPE33824.1 - 0.12 11.2 0.1 0.23 10.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EPE33824.1 - 4.4 6.2 6.3 38 3.1 0.2 3.2 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.17 EPE33824.1 - 9 5.0 8.3 9.4 4.9 0.1 3.4 4 0 0 4 4 4 0 Glucose inhibited division protein A Cnd3 PF12719.2 EPE33826.1 - 1.5e-91 306.4 2.3 1.5e-91 306.4 1.6 2.5 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EPE33826.1 - 9.3e-11 41.8 12.1 0.00011 22.4 1.1 5.6 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EPE33826.1 - 3e-07 29.9 8.2 0.26 11.4 0.0 7.3 8 0 0 8 8 8 1 HEAT repeat MMS19_N PF14500.1 EPE33826.1 - 0.0064 15.7 0.3 0.37 10.0 0.0 2.9 2 1 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF1546 PF07571.8 EPE33826.1 - 0.017 15.2 0.9 1.2 9.2 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) PALP PF00291.20 EPE33827.1 - 7.1e-61 206.1 0.1 8.4e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YtxH PF12732.2 EPE33828.1 - 0.013 15.8 0.4 0.036 14.4 0.1 1.9 2 0 0 2 2 2 0 YtxH-like protein Ribosomal_L19 PF01245.15 EPE33829.1 - 5.2e-20 71.3 0.1 8.1e-20 70.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 Peptidase_M13_N PF05649.8 EPE33830.1 - 2.7e-71 240.6 0.0 3.8e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EPE33830.1 - 7.1e-50 169.0 0.0 1.4e-49 168.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 UBA_2 PF08587.6 EPE33831.1 - 0.0026 17.8 3.1 41 4.4 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin associated domain (UBA) Terminase_5 PF06056.7 EPE33831.1 - 0.0053 16.2 0.0 25 4.5 0.0 3.8 4 0 0 4 4 4 1 Putative ATPase subunit of terminase (gpP-like) SAE2 PF08573.5 EPE33831.1 - 0.026 15.2 0.1 0.035 14.8 0.1 1.3 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Phage_XkdX PF09693.5 EPE33831.1 - 5.3 6.6 8.7 14 5.3 0.1 3.9 4 0 0 4 4 4 0 Phage uncharacterised protein (Phage_XkdX) DUF3328 PF11807.3 EPE33832.1 - 2.3e-54 184.3 0.2 3.2e-54 183.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4048 PF13257.1 EPE33833.1 - 1.2e-13 51.2 29.0 1.2e-11 44.7 6.9 3.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4048) TPR_MLP1_2 PF07926.7 EPE33833.1 - 0.012 15.3 0.2 0.019 14.6 0.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Bap31 PF05529.7 EPE33833.1 - 0.23 10.9 1.4 0.43 10.0 1.0 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DNA_ligase_A_N PF04675.9 EPE33834.1 - 5.8e-10 39.2 0.0 1.4e-09 37.9 0.0 1.6 2 0 0 2 2 2 1 DNA ligase N terminus Carb_anhydrase PF00194.16 EPE33835.1 - 6.7e-17 61.3 0.0 1.3e-16 60.4 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase NUDIX PF00293.23 EPE33836.1 - 7.9e-17 61.1 0.6 2.3e-16 59.6 0.2 1.9 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.6 EPE33836.1 - 3.2e-14 53.0 0.0 1.4e-13 51.0 0.0 2.0 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EPE33836.1 - 6.7e-09 35.0 0.5 1.2e-08 34.2 0.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Glyco_hydro_61 PF03443.9 EPE33840.1 - 3.3e-43 148.0 0.1 3.9e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Helicase_C_3 PF13625.1 EPE33841.1 - 2.6e-23 82.1 0.0 1.5e-22 79.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE33841.1 - 1e-14 54.8 0.0 3.1e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPE33841.1 - 1.7e-11 43.5 0.0 2.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE33841.1 - 4e-10 39.4 0.0 9.3e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-FPG_IleRS PF06827.9 EPE33842.1 - 0.00045 19.7 0.6 0.001 18.6 0.4 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zinc_ribbon_2 PF13240.1 EPE33842.1 - 0.0061 16.0 1.6 0.088 12.3 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain HypA PF01155.14 EPE33842.1 - 0.0091 15.6 0.5 0.011 15.3 0.3 1.3 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family zf-CHY PF05495.7 EPE33842.1 - 0.013 15.6 3.0 0.018 15.1 2.1 1.2 1 0 0 1 1 1 0 CHY zinc finger RNHCP PF12647.2 EPE33842.1 - 0.015 15.1 0.3 0.016 15.0 0.2 1.2 1 0 0 1 1 1 0 RNHCP domain zinc_ribbon_5 PF13719.1 EPE33842.1 - 0.031 13.8 5.2 0.45 10.1 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EPE33842.1 - 0.044 13.4 5.6 0.56 9.9 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EPE33842.1 - 0.055 13.4 5.0 0.098 12.6 3.4 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zf-RING_3 PF14369.1 EPE33842.1 - 0.056 13.4 2.8 0.12 12.3 1.9 1.7 1 1 0 1 1 1 0 zinc-finger C1_4 PF07975.7 EPE33842.1 - 0.076 13.0 4.4 0.15 12.0 2.9 1.5 1 1 0 1 1 1 0 TFIIH C1-like domain zf-C3HC4_3 PF13920.1 EPE33842.1 - 0.088 12.5 0.9 0.13 11.9 0.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.2 EPE33842.1 - 0.19 11.5 2.5 6.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 EPE33842.1 - 0.31 10.8 3.6 0.56 10.0 2.5 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EPE33842.1 - 0.48 9.7 5.6 1.3 8.3 3.9 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Evr1_Alr PF04777.8 EPE33842.1 - 0.63 9.9 2.6 3.3 7.6 1.8 2.0 1 1 0 1 1 1 0 Erv1 / Alr family zf-C2H2 PF00096.21 EPE33842.1 - 0.76 10.2 4.9 2.3 8.7 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type TFIIS_C PF01096.13 EPE33842.1 - 2 8.1 4.7 7.3 6.3 0.6 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-H2C2_2 PF13465.1 EPE33842.1 - 2.8 8.4 7.7 11 6.5 1.8 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Proteasome PF00227.21 EPE33843.1 - 2.6e-54 183.4 0.1 3.5e-54 182.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPE33843.1 - 2.5e-13 49.0 0.1 2.5e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAD-oxidase_C PF02913.14 EPE33844.1 - 8.3e-51 172.6 0.0 1.2e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EPE33844.1 - 1e-34 119.0 0.7 2.1e-34 117.9 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain NPHI_C PF08469.5 EPE33844.1 - 0.1 12.5 0.1 0.56 10.0 0.0 2.3 3 0 0 3 3 3 0 Nucleoside triphosphatase I C-terminal Ferritin_2 PF13668.1 EPE33845.1 - 2e-08 34.2 0.1 2.8e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain CoA_transf_3 PF02515.12 EPE33846.1 - 8.5e-50 168.6 0.0 1.1e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Dynamin_M PF01031.15 EPE33848.1 - 1.3e-105 352.4 0.4 2.5e-105 351.4 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EPE33848.1 - 1.5e-55 187.6 0.0 2.7e-55 186.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EPE33848.1 - 4.2e-29 100.2 4.1 8.9e-29 99.2 2.8 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EPE33848.1 - 0.00041 20.2 0.9 0.0036 17.2 0.2 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EPE33848.1 - 0.0042 17.5 0.0 0.042 14.3 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein PfkB PF00294.19 EPE33849.1 - 1.5e-51 175.3 0.4 1.8e-51 175.0 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase WD40 PF00400.27 EPE33850.1 - 2.8e-32 109.3 10.7 5.2e-10 38.8 0.1 7.4 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EPE33850.1 - 9.4e-05 22.2 0.1 0.084 12.5 0.0 3.2 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 EPE33850.1 - 0.00051 19.5 0.0 0.09 12.1 0.0 3.1 2 1 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain IKI3 PF04762.7 EPE33850.1 - 0.0069 14.2 0.1 0.11 10.3 0.0 2.2 2 1 0 2 2 2 1 IKI3 family CLTH PF10607.4 EPE33850.1 - 0.011 15.4 0.1 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Coatomer_WDAD PF04053.9 EPE33850.1 - 0.019 13.7 0.0 0.086 11.6 0.0 2.0 2 1 1 3 3 3 0 Coatomer WD associated region Nbas_N PF15492.1 EPE33850.1 - 0.072 12.1 0.0 1.5 7.8 0.0 2.5 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Str_synth PF03088.11 EPE33850.1 - 0.074 13.1 0.0 8.6 6.4 0.0 3.3 3 0 0 3 3 3 0 Strictosidine synthase ATP-synt_ab PF00006.20 EPE33851.1 - 2.5e-114 380.1 0.0 3.6e-114 379.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPE33851.1 - 8.3e-20 71.3 0.5 1.8e-19 70.2 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPE33851.1 - 5e-15 55.4 3.9 1.1e-14 54.3 2.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain adh_short PF00106.20 EPE33852.1 - 3.2e-17 62.9 0.6 3.2e-17 62.9 0.4 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE33852.1 - 6.4e-09 35.7 1.0 7.8e-09 35.4 0.1 1.5 2 0 0 2 2 2 1 KR domain Bac_rhodopsin PF01036.13 EPE33853.1 - 4.1e-49 166.8 19.7 4.7e-49 166.6 13.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Intg_mem_TP0381 PF09529.5 EPE33853.1 - 0.01 15.1 5.4 0.14 11.3 0.9 2.5 2 1 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) DUF788 PF05620.6 EPE33853.1 - 2 8.2 4.6 7.8 6.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF788) ACT_7 PF13840.1 EPE33854.1 - 2.4e-19 68.5 0.0 1.4e-16 59.7 0.0 2.7 2 0 0 2 2 2 2 ACT domain CTD_bind PF04818.8 EPE33855.1 - 6.4e-07 29.5 0.4 2e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. HpaP PF09483.5 EPE33856.1 - 2.3 8.1 8.2 2.8 7.8 5.7 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Exo_endo_phos PF03372.18 EPE33857.1 - 7e-26 91.6 2.2 1e-25 91.1 0.5 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EPE33857.1 - 0.0079 16.0 0.3 0.043 13.7 0.1 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPE33857.1 - 0.036 13.8 0.5 0.36 10.6 0.0 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region GFA PF04828.9 EPE33858.1 - 7.7e-11 41.7 1.8 7.7e-11 41.7 1.2 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-RING_2 PF13639.1 EPE33859.1 - 1.3e-09 37.7 12.2 1.3e-09 37.7 8.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPE33859.1 - 2.5e-09 36.6 8.3 2.5e-09 36.6 5.7 2.3 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE33859.1 - 8.1e-08 31.8 9.5 8.1e-08 31.8 6.6 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPE33859.1 - 1.6e-07 31.2 12.0 1.6e-07 31.2 8.3 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE33859.1 - 1.1e-06 28.1 10.1 1.1e-06 28.1 7.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPE33859.1 - 6.7e-05 22.6 10.0 0.00029 20.6 6.9 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPE33859.1 - 0.00013 21.4 13.8 0.002 17.6 2.1 3.3 3 0 0 3 3 3 2 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EPE33859.1 - 0.02 14.6 6.0 0.024 14.3 2.3 2.6 1 1 1 2 2 2 0 RING-type zinc-finger zf-MIZ PF02891.15 EPE33859.1 - 0.023 14.2 9.5 0.059 12.8 6.6 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 EPE33859.1 - 0.43 10.4 6.4 1.7 8.5 4.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EPE33859.1 - 1.1 9.3 10.7 4.3 7.5 7.4 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EPE33859.1 - 1.2 8.7 11.6 40 3.8 7.8 3.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PrpF PF04303.8 EPE33860.1 - 3.7e-101 338.5 0.6 4.5e-94 315.2 0.1 2.0 2 0 0 2 2 2 2 PrpF protein BMF PF15185.1 EPE33860.1 - 0.044 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis FMN_bind PF04205.9 EPE33860.1 - 0.063 13.4 0.1 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 FMN-binding domain LRR_adjacent PF08191.6 EPE33860.1 - 0.17 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 LRR adjacent MFS_1 PF07690.11 EPE33861.1 - 9.4e-34 116.6 21.6 1.4e-33 116.1 15.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Orthoreo_P10 PF07204.6 EPE33861.1 - 0.088 12.5 0.8 3.5 7.4 0.0 3.0 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 Sugar_tr PF00083.19 EPE33862.1 - 4.1e-121 404.7 34.1 4.6e-121 404.5 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE33862.1 - 8.8e-28 97.0 30.3 8.8e-28 97.0 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SecE PF00584.15 EPE33862.1 - 0.047 13.2 0.1 0.047 13.2 0.0 4.1 5 0 0 5 5 5 0 SecE/Sec61-gamma subunits of protein translocation complex DUF4342 PF14242.1 EPE33862.1 - 0.2 11.4 1.5 0.48 10.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Fungal_trans PF04082.13 EPE33863.1 - 5.8e-29 100.7 0.6 8.5e-29 100.2 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_BLRF2 PF05812.7 EPE33863.1 - 0.057 13.2 0.6 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein TMEM61 PF15105.1 EPE33863.1 - 0.083 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 TMEM61 protein family Mito_carr PF00153.22 EPE33864.1 - 3.2e-60 199.8 10.1 7.6e-22 76.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tail_P2_I PF09684.5 EPE33864.1 - 0.057 12.9 0.3 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) Tim17 PF02466.14 EPE33864.1 - 2.8 8.0 11.5 3.7 7.6 0.4 3.4 1 1 2 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family E1_DerP2_DerF2 PF02221.10 EPE33865.1 - 4.1e-05 23.8 0.0 5.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 ML domain zf-met2 PF12907.2 EPE33866.1 - 0.0014 18.5 3.5 0.0039 17.1 2.4 1.8 1 1 0 1 1 1 1 Zinc-binding zf-C2H2_2 PF12756.2 EPE33866.1 - 0.0075 16.3 0.2 0.0085 16.1 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 EPE33866.1 - 0.029 14.1 1.0 0.046 13.4 0.7 1.4 1 0 0 1 1 1 0 BED zinc finger DUF1364 PF07102.7 EPE33866.1 - 0.059 13.2 0.4 0.072 12.9 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1364) TrkH PF02386.11 EPE33868.1 - 1.2e-117 392.4 16.5 6.2e-117 390.1 7.5 2.1 2 0 0 2 2 2 2 Cation transport protein DUF3943 PF13084.1 EPE33869.1 - 0.022 14.3 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) EHN PF06441.7 EPE33870.1 - 1.4e-21 76.4 0.1 2.3e-21 75.8 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Hid1 PF12722.2 EPE33871.1 - 1.7e-253 843.3 0.6 5.1e-253 841.8 0.4 1.6 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EPE33871.1 - 2.4e-78 263.9 0.0 4.8e-78 262.9 0.0 1.4 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.6 EPE33871.1 - 4.5e-29 101.1 0.1 1.9e-28 99.1 0.0 2.1 2 0 0 2 2 2 1 Nuclear pore complex component AMP-binding PF00501.23 EPE33872.1 - 1.2e-12 47.0 0.0 1.9e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme PhoD PF09423.5 EPE33873.1 - 3.4e-59 200.6 0.0 4.6e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase GH97_N PF14508.1 EPE33873.1 - 0.13 11.2 1.2 1.1 8.2 0.0 2.5 2 1 1 3 3 3 0 Glycosyl-hydrolase 97 N-terminal BBS2_C PF14782.1 EPE33873.1 - 0.29 9.6 0.0 0.44 9.0 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal EF-hand_7 PF13499.1 EPE33874.1 - 1.7e-25 88.9 1.6 7.6e-17 61.2 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EPE33874.1 - 2.8e-24 82.5 4.5 2.6e-09 35.6 0.4 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EPE33874.1 - 9.3e-22 76.4 4.4 1.9e-14 52.9 0.2 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EPE33874.1 - 4.4e-19 66.5 1.7 4.3e-07 29.2 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EPE33874.1 - 1.1e-13 49.8 3.0 7.1e-06 25.1 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 EPE33874.1 - 2.2e-09 37.0 1.6 1.2e-07 31.4 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain UPF0154 PF03672.8 EPE33874.1 - 9.8e-05 21.9 0.1 0.42 10.2 0.0 2.7 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.2 EPE33874.1 - 0.00012 21.8 1.9 0.0027 17.3 0.2 2.6 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EPE33874.1 - 0.067 13.2 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PB1 PF00564.19 EPE33874.1 - 0.067 12.8 0.0 1.6 8.4 0.0 2.7 3 0 0 3 3 3 0 PB1 domain LSM PF01423.17 EPE33877.1 - 1.2e-15 56.7 0.0 1.9e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPE33877.1 - 0.0073 16.1 0.0 0.0097 15.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.6 EPE33877.1 - 2.9 6.3 18.3 3.6 5.9 12.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PPR_2 PF13041.1 EPE33878.1 - 1.8e-17 63.0 0.5 0.0005 19.9 0.0 6.5 3 2 4 7 7 7 4 PPR repeat family PPR_3 PF13812.1 EPE33878.1 - 7.2e-15 53.9 2.1 0.00024 21.1 0.0 7.1 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 EPE33878.1 - 7.3e-10 38.1 5.2 0.04 13.8 0.1 6.7 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.2 EPE33878.1 - 4.1e-08 32.5 2.3 0.067 12.6 0.0 5.3 5 0 0 5 5 5 2 PPR repeat TPR_14 PF13428.1 EPE33878.1 - 0.00046 20.5 0.1 8.9 7.2 0.0 5.2 6 2 1 7 7 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPE33878.1 - 0.0023 17.8 0.0 7.2 6.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPE33878.1 - 0.0051 16.6 0.4 3 7.9 0.1 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPE33878.1 - 0.0081 16.4 0.0 9.1 6.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE33878.1 - 0.012 15.3 0.1 2.1 8.3 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EPE33878.1 - 0.026 14.6 0.0 2.9 8.0 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EPE33878.1 - 0.16 11.6 1.2 16 5.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 EPE33878.1 - 0.79 9.5 3.1 6.5 6.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 EPE33879.1 - 1.9e-05 24.6 19.7 0.034 14.4 0.0 3.6 2 1 1 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE33879.1 - 1.2 9.5 22.8 0.2 12.0 0.3 3.7 2 1 0 3 3 3 0 Zinc finger, C2H2 type Ribosomal_L13 PF00572.13 EPE33880.1 - 1.2e-37 128.8 0.0 1.6e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Sod_Cu PF00080.15 EPE33881.1 - 6.6e-14 52.2 0.0 1.4e-13 51.2 0.0 1.5 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EPE33881.1 - 1.7e-11 44.0 0.0 2.8e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain TPR_11 PF13414.1 EPE33882.1 - 7e-15 54.4 0.9 1.1e-09 37.7 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EPE33882.1 - 9.6e-15 53.4 3.6 4.7e-07 29.1 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPE33882.1 - 3.1e-13 48.5 3.7 1.7e-05 24.4 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPE33882.1 - 2e-08 33.4 0.2 0.0011 18.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.19 EPE33882.1 - 8e-08 31.8 0.5 1.5e-07 30.9 0.3 1.5 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.1 EPE33882.1 - 1.3e-07 31.4 0.3 0.00011 22.1 0.0 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPE33882.1 - 1.7e-07 30.4 0.1 6.1e-06 25.6 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPE33882.1 - 1.3e-05 25.3 0.0 5.7 7.6 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE33882.1 - 0.00082 19.9 0.2 0.0051 17.4 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EPE33882.1 - 0.00087 19.3 0.0 0.052 13.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE33882.1 - 0.008 16.7 0.0 0.12 13.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPE33882.1 - 0.011 15.5 3.1 2.1 8.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Hemerythrin PF01814.18 EPE33883.1 - 9.1e-12 45.2 4.8 1.6e-11 44.4 3.4 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain NTP_transf_3 PF12804.2 EPE33884.1 - 6.6e-08 32.7 0.1 1.2e-07 31.9 0.1 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain MoeA_N PF03453.12 EPE33885.1 - 2e-16 59.7 0.0 2.5e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) SET PF00856.23 EPE33886.1 - 2.5e-10 40.9 0.2 2.1e-09 37.8 0.1 2.2 1 1 0 1 1 1 1 SET domain HET PF06985.6 EPE33887.1 - 4.9e-33 114.2 0.0 1e-32 113.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Uricase PF01014.13 EPE33888.1 - 7e-82 272.3 0.6 4.6e-42 143.3 0.6 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.1 EPE33889.1 - 1.5e-135 451.5 4.7 8.4e-134 445.8 2.7 2.5 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EPE33889.1 - 3.6e-88 294.3 0.6 3.3e-87 291.2 0.3 2.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EPE33889.1 - 6.2e-41 138.9 0.0 5e-40 136.0 0.0 2.5 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EPE33889.1 - 4.3e-29 100.2 0.3 3.5e-27 94.1 0.0 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EPE33889.1 - 1.4e-15 56.7 6.0 3.8e-15 55.3 4.2 1.8 1 0 0 1 1 1 1 Hr1 repeat HEAT_2 PF13646.1 EPE33889.1 - 9.7e-05 22.5 2.0 1.1 9.5 0.0 5.6 6 0 0 6 6 6 1 HEAT repeats Uds1 PF15456.1 EPE33889.1 - 0.0025 17.7 6.2 0.01 15.7 4.3 2.1 1 0 0 1 1 1 1 Up-regulated During Septation DUF724 PF05266.9 EPE33889.1 - 0.11 12.1 3.5 0.27 10.8 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) eIF-3c_N PF05470.7 EPE33890.1 - 3.9e-172 573.4 24.9 1.3e-141 472.6 1.2 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EPE33890.1 - 6.3e-15 55.3 1.1 3e-14 53.2 0.1 2.6 2 0 0 2 2 2 1 PCI domain AAR2 PF05282.6 EPE33892.1 - 9e-58 195.9 0.5 1.4e-57 195.2 0.0 1.5 2 0 0 2 2 2 1 AAR2 protein DUF3934 PF13070.1 EPE33892.1 - 0.14 12.4 0.1 0.34 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) Ribosomal_S11 PF00411.14 EPE33893.1 - 2.8e-40 136.9 0.5 3.4e-40 136.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 EPE33893.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) PDH PF02153.12 EPE33894.1 - 9.4e-13 47.6 0.0 1.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EPE33894.1 - 2.2e-07 30.8 0.0 6.9e-07 29.2 0.0 1.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EPE33894.1 - 1.4e-05 25.4 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EPE33894.1 - 4.2e-05 23.0 0.0 7.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EPE33894.1 - 0.00052 19.2 0.0 0.00098 18.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EPE33894.1 - 0.0025 17.4 0.0 0.043 13.4 0.0 2.1 1 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EPE33894.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.7 EPE33894.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Ribosomal_S9 PF00380.14 EPE33895.1 - 8.1e-40 135.8 0.3 9.1e-40 135.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EPE33895.1 - 0.031 11.7 0.0 0.036 11.5 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein EAP30 PF04157.11 EPE33896.1 - 8.2e-66 221.3 0.0 9.3e-66 221.1 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DUF3384 PF11864.3 EPE33898.1 - 1.9e-89 300.3 0.0 3.4e-89 299.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EPE33898.1 - 2.6e-55 186.7 0.0 4.8e-55 185.8 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EPE33898.1 - 1.8e-32 112.7 6.2 6.2e-31 107.7 0.6 2.8 3 0 0 3 3 3 2 Tuberin CAS_CSE1 PF03378.10 EPE33899.1 - 2.2e-177 589.7 0.0 8.1e-177 587.8 0.0 2.0 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EPE33899.1 - 8.5e-158 524.7 0.3 1.3e-157 524.1 0.2 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EPE33899.1 - 4.9e-13 48.7 0.1 4.3e-12 45.7 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EPE33899.1 - 0.0055 16.6 3.0 1.5 8.6 0.1 4.8 4 1 0 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.1 EPE33899.1 - 0.011 15.9 0.2 0.33 11.2 0.0 3.5 5 0 0 5 5 5 0 HEAT repeats Glyco_hydro_10 PF00331.15 EPE33900.1 - 2.4e-101 338.9 0.8 2.8e-101 338.7 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EPE33900.1 - 2.7e-07 30.0 11.2 6e-07 29.0 7.8 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain LRR_4 PF12799.2 EPE33901.1 - 0.0038 16.8 1.2 3.2 7.4 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Phos_pyr_kin PF08543.7 EPE33902.1 - 5.9e-83 277.8 1.7 5.9e-83 277.8 1.2 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EPE33902.1 - 6e-50 169.9 2.0 3.4e-49 167.4 1.4 1.9 1 1 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EPE33902.1 - 7.1e-10 38.5 0.0 1.2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 EPE33902.1 - 0.02 14.0 0.6 0.23 10.6 0.0 2.3 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 EPE33902.1 - 0.02 14.1 2.9 0.024 13.9 1.1 1.9 2 1 0 2 2 2 0 Carbohydrate kinase HECT PF00632.20 EPE33903.1 - 4.6e-85 285.5 0.0 8.1e-85 284.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EPE33903.1 - 0.0027 17.1 0.1 0.012 15.1 0.1 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif PG_binding_2 PF08823.6 EPE33903.1 - 0.0042 17.1 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Sial-lect-inser PF09264.5 EPE33903.1 - 0.1 11.9 1.0 0.2 10.9 0.7 1.4 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion Piwi PF02171.12 EPE33904.1 - 8.2e-75 251.5 0.0 1.1e-74 251.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EPE33904.1 - 2.1e-15 55.8 0.1 4.1e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EPE33904.1 - 1.1e-11 44.1 0.0 2.6e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 PAZ domain MFS_1 PF07690.11 EPE33905.1 - 1.7e-40 138.8 48.7 5e-40 137.2 33.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE33905.1 - 2.7e-13 48.9 23.6 7.6e-13 47.5 16.3 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cation_efflux PF01545.16 EPE33905.1 - 2 7.4 13.3 0.07 12.1 1.0 3.2 2 1 1 3 3 3 0 Cation efflux family Cren7 PF11520.3 EPE33907.1 - 0.0022 17.5 1.3 0.0034 16.9 0.9 1.3 1 0 0 1 1 1 1 Chromatin protein Cren7 Cyclin_N PF00134.18 EPE33909.1 - 1.7e-14 53.4 0.1 2.1e-13 49.9 0.0 2.4 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin PF08613.6 EPE33909.1 - 1.3e-10 41.9 0.0 2.8e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Cyclin DUF2647 PF10839.3 EPE33910.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) DUF3596 PF12167.3 EPE33911.1 - 0.083 12.4 0.2 0.36 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) HARP PF07443.8 EPE33911.1 - 0.2 11.0 0.1 0.45 9.9 0.0 1.5 1 0 0 1 1 1 0 HepA-related protein (HARP) Complex1_LYR_2 PF13233.1 EPE33912.1 - 1.2e-19 70.6 0.3 1.4e-19 70.4 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like MMR_HSR1 PF01926.18 EPE33913.1 - 6.1e-20 71.3 0.0 9.3e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPE33913.1 - 2.5e-06 27.3 0.0 0.0015 18.3 0.1 2.2 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EPE33913.1 - 1.2e-05 24.8 0.0 0.00035 20.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPE33913.1 - 0.0013 17.8 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EPE33913.1 - 0.0015 17.7 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 EPE33913.1 - 0.0015 17.8 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.13 EPE33913.1 - 0.003 16.6 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Septin FeoB_N PF02421.13 EPE33913.1 - 0.014 14.6 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.1 EPE33913.1 - 0.028 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ENTH PF01417.15 EPE33914.1 - 2.8e-50 169.3 0.2 4.9e-50 168.5 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EPE33914.1 - 0.0015 17.3 0.0 0.0022 16.7 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Tim54 PF11711.3 EPE33914.1 - 0.0023 16.5 3.8 0.0023 16.5 2.7 1.5 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 VHS PF00790.14 EPE33914.1 - 0.0024 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 VHS domain DUF4264 PF14084.1 EPE33914.1 - 0.016 14.5 0.2 0.028 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) UIM PF02809.15 EPE33914.1 - 0.052 13.1 3.1 0.19 11.3 0.1 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF1720 PF08226.6 EPE33914.1 - 0.48 10.5 100.1 45 4.2 10.5 4.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1720) PAT1 PF09770.4 EPE33914.1 - 6 4.9 42.1 11 4.0 29.2 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EF-hand_8 PF13833.1 EPE33915.1 - 9.6e-17 60.3 5.1 7e-10 38.3 0.5 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EPE33915.1 - 2.3e-15 54.6 7.4 1.3e-06 27.2 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EPE33915.1 - 1e-13 49.8 6.2 1.4e-06 27.6 0.3 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EPE33915.1 - 1.9e-13 50.3 4.0 1.1e-07 31.9 0.2 2.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EPE33915.1 - 0.0016 18.1 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 EPE33915.1 - 0.0049 16.1 7.3 0.24 10.7 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 EPE33915.1 - 0.0076 16.1 0.0 0.037 13.9 0.0 2.1 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.8 EPE33915.1 - 0.15 11.5 0.0 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Caleosin related protein Nup96 PF12110.3 EPE33916.1 - 9.9e-86 287.4 0.3 1.9e-85 286.5 0.2 1.5 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EPE33916.1 - 1.5e-49 167.4 0.1 2.5e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EPE33916.1 - 1.2e-14 54.5 377.6 2.1e-07 31.1 34.5 11.0 3 2 6 10 10 10 6 Nucleoporin FG repeat region EcsC PF12787.2 EPE33916.1 - 0.43 9.9 1.4 0.65 9.3 0.0 2.0 2 0 0 2 2 2 0 EcsC protein family DUF3407 PF11887.3 EPE33917.1 - 0.053 12.7 0.5 0.83 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3407) Baculo_PEP_C PF04513.7 EPE33917.1 - 0.73 9.6 4.3 11 5.8 0.0 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus A_deaminase PF00962.17 EPE33919.1 - 2.8e-42 144.7 0.0 6.3e-42 143.6 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase TPR_8 PF13181.1 EPE33919.1 - 0.092 12.5 0.4 0.66 9.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP40_C PF05022.7 EPE33920.1 - 5.2e-26 90.9 0.6 1.6e-25 89.4 0.4 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain Sec3_C PF09763.4 EPE33921.1 - 1.7e-228 760.3 0.1 2.2e-228 759.9 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EPE33921.1 - 1.1e-27 95.6 0.0 2.2e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 EPE33921.1 - 9.9e-05 22.4 0.1 0.00038 20.5 0.1 2.0 1 0 0 1 1 1 1 Sec3 exocyst complex subunit Vps52 PF04129.7 EPE33921.1 - 0.00082 18.0 0.8 0.00082 18.0 0.6 1.6 2 0 0 2 2 2 1 Vps52 / Sac2 family CobT PF06213.7 EPE33922.1 - 5 6.1 14.8 6.3 5.8 10.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GTP_EFTU PF00009.22 EPE33923.1 - 3.7e-57 192.8 0.3 8.2e-57 191.6 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EPE33923.1 - 1.1e-32 111.6 0.0 2.3e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EPE33923.1 - 4.3e-31 106.9 0.0 1.7e-30 105.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EPE33923.1 - 1.7e-24 85.4 0.0 9.1e-23 79.9 0.0 2.6 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPE33923.1 - 2.3e-14 53.2 0.1 7.3e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 IMS PF00817.15 EPE33924.1 - 2.3e-40 137.8 0.8 4.2e-40 136.9 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EPE33924.1 - 2.1e-16 60.0 0.0 5.7e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EPE33924.1 - 0.003 17.5 0.0 0.0088 16.0 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif RPEL PF02755.10 EPE33925.1 - 2.4e-29 99.7 20.6 2e-10 39.6 1.5 3.9 4 0 0 4 4 4 3 RPEL repeat Rotamase_3 PF13616.1 EPE33925.1 - 0.064 13.5 0.4 0.55 10.5 0.0 2.1 1 1 1 2 2 2 0 PPIC-type PPIASE domain Clr5 PF14420.1 EPE33927.1 - 3.5e-19 68.4 0.4 1e-18 66.9 0.3 1.9 1 0 0 1 1 1 1 Clr5 domain FLO_LFY PF01698.11 EPE33927.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Ribosomal_S8 PF00410.14 EPE33929.1 - 1.6e-23 82.9 0.0 1.9e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.15 EPE33930.1 - 9.9e-97 323.9 0.1 1.6e-96 323.3 0.0 1.3 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SET PF00856.23 EPE33933.1 - 5.1e-12 46.3 4.1 1.4e-11 44.9 0.3 3.0 3 1 0 3 3 3 1 SET domain EGF_3 PF12947.2 EPE33933.1 - 0.034 14.1 3.8 0.084 12.8 1.3 2.6 2 1 0 2 2 2 0 EGF domain GST_N_2 PF13409.1 EPE33934.1 - 3.2e-09 36.6 0.0 5.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPE33934.1 - 3.6e-08 33.5 0.0 6.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPE33934.1 - 3.1e-06 27.0 0.0 4.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPE33934.1 - 6.6e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPE33934.1 - 0.0051 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glyco_hydro_92 PF07971.7 EPE33935.1 - 1.2e-138 462.9 0.1 1.4e-115 386.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 92 Gln-synt_C PF00120.19 EPE33936.1 - 1.5e-48 165.2 0.0 2.2e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EPE33936.1 - 3.7e-28 98.8 0.2 4.6e-27 95.2 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase FAD-SLDH PF12318.3 EPE33936.1 - 0.003 17.2 0.2 0.0096 15.6 0.2 1.8 1 0 0 1 1 1 1 Membrane bound FAD containing D-sorbitol dehydrogenase TctB PF07331.6 EPE33937.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF1180 PF06679.7 EPE33937.1 - 0.044 13.6 0.2 0.044 13.6 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) TMEM154 PF15102.1 EPE33937.1 - 0.081 12.6 0.4 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family YebO PF13974.1 EPE33937.1 - 0.57 10.0 1.8 1.2 8.9 1.2 1.6 1 0 0 1 1 1 0 YebO-like protein KH_1 PF00013.24 EPE33938.1 - 0.014 15.0 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 KH domain Shisa PF13908.1 EPE33940.1 - 0.0028 17.8 0.2 0.0068 16.6 0.0 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Aldo_ket_red PF00248.16 EPE33941.1 - 9.1e-43 146.0 0.0 1.2e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 EPE33942.1 - 5.3e-17 61.5 2.6 7.6e-17 61.0 1.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE33942.1 - 7.9e-09 35.2 10.3 1.3e-08 34.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NGP1NT PF08153.7 EPE33943.1 - 6e-47 158.8 0.1 1e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EPE33943.1 - 3.3e-19 68.9 0.0 6.8e-15 55.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE33943.1 - 0.00044 19.5 0.1 0.002 17.4 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 EPE33943.1 - 0.0013 17.9 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.18 EPE33943.1 - 0.0025 17.6 2.8 0.5 10.1 0.0 3.6 3 1 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.22 EPE33943.1 - 0.0039 16.6 0.0 0.36 10.2 0.0 3.0 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPE33943.1 - 0.009 15.2 0.0 0.021 13.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 CENP-T PF15511.1 EPE33943.1 - 9.7 5.3 15.6 15 4.7 10.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T adh_short PF00106.20 EPE33946.1 - 1.9e-18 66.9 1.9 3.5e-16 59.5 0.1 2.7 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EPE33946.1 - 3.4e-06 26.8 0.0 5.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE33946.1 - 1.8e-05 24.6 0.1 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPE33946.1 - 0.013 14.9 0.1 0.019 14.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Rad4 PF03835.10 EPE33947.1 - 7.1e-17 61.1 4.2 1.7e-16 59.9 2.9 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EPE33947.1 - 4.2e-14 52.7 1.6 1.5e-13 50.9 1.1 2.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily TrkH PF02386.11 EPE33949.1 - 3.7e-95 318.4 11.0 8.4e-89 297.5 3.0 2.1 2 0 0 2 2 2 2 Cation transport protein DUF4381 PF14316.1 EPE33949.1 - 1.1 9.3 4.6 3.1 7.9 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Ferritin_2 PF13668.1 EPE33950.1 - 0.0085 16.0 0.2 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Ferritin-like domain RCR PF12273.3 EPE33952.1 - 0.00076 20.0 0.0 0.00099 19.6 0.0 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DAP10 PF07213.6 EPE33952.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 DAP10 membrane protein Ribonuclease PF00545.15 EPE33955.1 - 2.3e-16 59.6 0.0 3.4e-16 59.0 0.0 1.3 1 1 0 1 1 1 1 ribonuclease DIM PF08194.7 EPE33955.1 - 0.023 14.6 1.6 2.4 8.1 0.7 2.3 2 0 0 2 2 2 0 DIM protein Como_SCP PF02248.11 EPE33955.1 - 0.094 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Small coat protein DUF3632 PF12311.3 EPE33956.1 - 1.2e-38 132.8 2.2 1.4e-38 132.5 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) FKBP_C PF00254.23 EPE33958.1 - 1.8e-30 104.7 0.0 2.7e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-Apc11 PF12861.2 EPE33959.1 - 1.5e-44 149.7 9.9 1.7e-44 149.5 6.9 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EPE33959.1 - 2.3e-32 110.9 11.2 2.7e-32 110.6 7.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPE33959.1 - 5.3e-10 38.9 14.6 1.7e-09 37.3 10.1 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPE33959.1 - 6.8e-06 25.7 11.5 2e-05 24.2 6.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE33959.1 - 7.6e-05 22.3 13.5 0.0015 18.1 9.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE33959.1 - 8.1e-05 22.5 14.0 0.00055 19.9 9.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE33959.1 - 0.00014 21.4 15.9 0.00074 19.1 11.1 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPE33959.1 - 0.00055 19.7 2.2 0.00055 19.7 1.5 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EPE33959.1 - 0.00069 19.5 16.2 0.0075 16.2 11.2 2.6 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.1 EPE33959.1 - 0.026 14.0 14.6 0.076 12.6 8.0 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EPE33959.1 - 0.037 13.5 7.7 0.067 12.7 5.2 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-DBF PF07535.7 EPE33959.1 - 0.09 12.4 1.1 1.8 8.2 0.2 2.4 2 0 0 2 2 2 0 DBF zinc finger zf-RING-like PF08746.6 EPE33959.1 - 0.6 10.1 15.7 2.9 7.9 10.9 2.1 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.2 EPE33959.1 - 0.77 9.8 13.2 2.3 8.3 9.1 1.9 1 1 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EPE33959.1 - 1.5 8.6 9.5 0.32 10.7 4.0 2.0 2 1 0 2 2 2 0 RING-type zinc-finger UPF0506 PF11703.3 EPE33959.1 - 1.9 8.4 10.2 2.8 7.9 3.2 2.1 1 1 1 2 2 2 0 UPF0506 zf-HC5HC2H_2 PF13832.1 EPE33959.1 - 5.6 6.9 11.4 6.4 6.8 4.4 2.4 1 1 1 2 2 2 0 PHD-zinc-finger like domain SCRL PF06876.7 EPE33959.1 - 5.8 6.9 12.3 97 3.0 8.5 2.2 1 1 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein Opy2 PF09463.5 EPE33959.1 - 9.5 6.4 12.0 29 4.8 5.0 2.3 2 0 0 2 2 2 0 Opy2 protein Rhodanese PF00581.15 EPE33960.1 - 2.6e-21 76.0 0.0 5e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Methyltransf_23 PF13489.1 EPE33961.1 - 3.9e-23 81.9 0.0 5.7e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE33961.1 - 1.1e-06 29.1 0.0 1.1e-05 26.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE33961.1 - 1.5e-05 24.6 0.0 0.00018 21.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE33961.1 - 0.00016 22.1 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE33961.1 - 0.0018 18.5 0.0 0.012 15.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EPE33961.1 - 0.0032 17.4 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EPE33961.1 - 0.0046 16.0 0.0 0.0084 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EPE33961.1 - 0.008 16.6 0.0 0.071 13.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EPE33961.1 - 0.035 13.2 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EPE33961.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 EPE33961.1 - 0.062 12.4 0.1 0.28 10.3 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase GST_N PF02798.15 EPE33962.1 - 1.8e-18 66.4 0.0 2.9e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPE33962.1 - 1.2e-15 57.4 0.0 2.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPE33962.1 - 1.9e-13 50.1 0.0 3.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE33962.1 - 4.4e-08 32.8 0.1 8.7e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPE33962.1 - 5.5e-08 32.6 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPE33962.1 - 0.085 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain bZIP_1 PF00170.16 EPE33963.1 - 0.0017 18.2 2.8 0.0017 18.2 1.9 1.6 2 0 0 2 2 1 1 bZIP transcription factor Prominin PF05478.6 EPE33963.1 - 0.0027 15.3 3.3 0.0031 15.1 2.3 1.0 1 0 0 1 1 1 1 Prominin Jnk-SapK_ap_N PF09744.4 EPE33963.1 - 0.0036 17.3 3.7 0.0044 17.0 2.5 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 COG5 PF10392.4 EPE33963.1 - 0.0054 16.6 3.3 0.0069 16.3 2.3 1.1 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Hemerythrin PF01814.18 EPE33963.1 - 0.0092 16.1 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Phage_GPO PF05929.6 EPE33963.1 - 0.01 15.0 1.8 0.012 14.8 1.3 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CCDC155 PF14662.1 EPE33963.1 - 0.012 15.1 4.7 0.014 15.0 3.2 1.0 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 EPE33963.1 - 0.018 15.3 5.1 0.026 14.8 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) HAP1_N PF04849.8 EPE33963.1 - 0.023 13.6 6.9 0.082 11.8 4.8 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region BLOC1_2 PF10046.4 EPE33963.1 - 0.025 14.6 3.6 0.054 13.6 0.4 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TSC22 PF01166.13 EPE33963.1 - 0.034 14.1 2.7 0.034 14.1 1.9 1.8 1 1 0 2 2 1 0 TSC-22/dip/bun family IncA PF04156.9 EPE33963.1 - 0.035 13.7 4.0 0.043 13.4 2.8 1.2 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.3 EPE33963.1 - 0.04 13.1 1.9 0.045 13.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-K PF11802.3 EPE33963.1 - 0.048 12.8 3.7 0.059 12.5 2.6 1.3 1 1 0 1 1 1 0 Centromere-associated protein K ADIP PF11559.3 EPE33963.1 - 0.056 13.3 6.6 0.074 12.9 4.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7_N PF15402.1 EPE33963.1 - 0.062 11.3 2.0 0.072 11.1 1.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 BRE1 PF08647.6 EPE33963.1 - 0.08 12.9 4.9 0.11 12.5 3.4 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Tropomyosin_1 PF12718.2 EPE33963.1 - 0.087 12.6 6.0 0.079 12.8 3.6 1.5 1 1 0 1 1 1 0 Tropomyosin like DivIVA PF05103.8 EPE33963.1 - 0.097 12.7 5.2 0.044 13.8 1.4 1.8 1 1 1 2 2 2 0 DivIVA protein Med9 PF07544.8 EPE33963.1 - 0.099 12.3 3.7 0.061 13.0 0.8 1.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Herpes_BLRF2 PF05812.7 EPE33963.1 - 0.11 12.2 6.3 0.053 13.3 2.1 1.9 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Atg14 PF10186.4 EPE33963.1 - 0.11 11.3 4.8 0.13 11.1 3.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sipho_Gp157 PF05565.6 EPE33963.1 - 0.11 12.0 2.3 0.15 11.6 1.6 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 WD40_alt PF14077.1 EPE33963.1 - 0.12 12.0 0.9 0.24 11.0 0.6 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Snf7 PF03357.16 EPE33963.1 - 0.12 11.7 6.9 0.041 13.2 2.5 1.9 2 1 0 2 2 2 0 Snf7 V_ATPase_I PF01496.14 EPE33963.1 - 0.12 10.2 1.9 0.13 10.1 1.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin PF00804.20 EPE33963.1 - 0.14 12.3 4.3 0.19 11.9 3.0 1.3 1 0 0 1 1 1 0 Syntaxin DUF3810 PF12725.2 EPE33963.1 - 0.18 10.6 0.7 0.22 10.3 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) bZIP_2 PF07716.10 EPE33963.1 - 0.19 11.6 6.0 0.23 11.2 2.5 2.1 1 1 1 2 2 2 0 Basic region leucine zipper DUF2937 PF11157.3 EPE33963.1 - 0.34 10.2 1.4 0.4 9.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Prefoldin_2 PF01920.15 EPE33963.1 - 0.38 10.5 8.4 0.12 12.1 2.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit Cluap1 PF10234.4 EPE33963.1 - 0.4 9.8 4.8 0.52 9.4 3.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 GTSE1_N PF15259.1 EPE33963.1 - 0.49 10.3 4.1 0.63 9.9 2.9 1.1 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Vps51 PF08700.6 EPE33963.1 - 0.56 10.0 4.8 1.1 9.1 3.2 1.6 1 1 0 1 1 1 0 Vps51/Vps67 Snapin_Pallidin PF14712.1 EPE33963.1 - 0.65 10.3 5.8 4.4 7.6 4.0 2.3 1 1 0 1 1 1 0 Snapin/Pallidin DUF904 PF06005.7 EPE33963.1 - 0.82 10.0 9.6 0.2 12.0 4.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) M PF02370.11 EPE33963.1 - 0.91 10.0 6.6 0.17 12.2 1.8 2.1 2 0 0 2 2 1 0 M protein repeat DivIC PF04977.10 EPE33963.1 - 1.1 8.7 6.2 0.53 9.8 2.7 1.7 1 1 1 2 2 2 0 Septum formation initiator Syntaxin-6_N PF09177.6 EPE33963.1 - 1.2 9.5 4.5 1.1 9.6 1.1 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.3 EPE33963.1 - 1.3 8.8 9.4 2.5 7.9 6.5 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Sas10 PF09368.5 EPE33964.1 - 0.18 12.0 2.1 0.23 11.6 0.7 1.6 1 1 1 2 2 2 0 Sas10 C-terminal domain RFC1 PF08519.7 EPE33967.1 - 0.0018 18.0 0.2 0.0022 17.7 0.2 1.2 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain NPV_P10 PF05531.7 EPE33967.1 - 0.0038 17.4 0.1 0.0067 16.6 0.1 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 EPE33967.1 - 0.0085 16.4 4.4 0.012 15.9 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) HALZ PF02183.13 EPE33967.1 - 0.017 14.8 1.0 0.037 13.7 0.6 1.7 1 1 0 1 1 1 0 Homeobox associated leucine zipper WEMBL PF05701.6 EPE33967.1 - 0.019 13.4 8.9 0.026 12.9 6.2 1.2 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DivIC PF04977.10 EPE33967.1 - 0.054 12.9 0.2 0.054 12.9 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 EPE33967.1 - 0.057 13.3 2.2 0.21 11.5 1.5 1.9 1 1 1 2 2 2 0 bZIP transcription factor LPP PF04728.8 EPE33967.1 - 0.066 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper FlxA PF14282.1 EPE33967.1 - 0.068 13.1 7.7 0.28 11.1 5.4 1.8 1 1 0 1 1 1 0 FlxA-like protein DUF641 PF04859.7 EPE33967.1 - 0.23 11.1 2.7 0.18 11.5 0.5 1.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF904 PF06005.7 EPE33967.1 - 2.2 8.6 11.1 0.12 12.7 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) CENP-Q PF13094.1 EPE33967.1 - 2.3 8.2 10.7 5.1 7.0 7.4 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3090 PF11290.3 EPE33967.1 - 3.3 7.1 5.3 4.8 6.6 3.7 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3090) bZIP_2 PF07716.10 EPE33967.1 - 6 6.7 9.0 2 8.2 0.3 2.8 2 1 0 3 3 3 0 Basic region leucine zipper Uds1 PF15456.1 EPE33967.1 - 9.9 6.1 10.6 0.47 10.4 1.3 2.3 1 1 0 1 1 1 0 Up-regulated During Septation DUF4200 PF13863.1 EPE33968.1 - 0.0093 15.9 0.2 0.012 15.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Filament PF00038.16 EPE33968.1 - 0.016 14.6 0.1 0.018 14.5 0.1 1.0 1 0 0 1 1 1 0 Intermediate filament protein Siah-Interact_N PF09032.6 EPE33968.1 - 0.018 15.1 0.5 0.86 9.7 0.0 2.1 2 0 0 2 2 2 0 Siah interacting protein, N terminal DivIVA PF05103.8 EPE33968.1 - 0.031 14.3 0.5 0.3 11.1 0.4 1.9 1 1 0 1 1 1 0 DivIVA protein Bacillus_HBL PF05791.6 EPE33968.1 - 0.11 11.8 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Prefoldin_2 PF01920.15 EPE33968.1 - 0.7 9.6 2.7 3.2 7.5 1.9 1.7 1 1 0 1 1 1 0 Prefoldin subunit DUF221 PF02714.10 EPE33969.1 - 9.5e-109 363.1 25.8 9.5e-109 363.1 17.9 2.4 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPE33969.1 - 5e-43 146.3 0.4 5e-43 146.3 0.3 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EPE33969.1 - 1.8e-17 62.9 0.0 4.7e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EPE33969.1 - 3e-12 46.8 5.2 5.1e-05 23.7 0.1 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) VSG_B PF13206.1 EPE33969.1 - 0.0038 16.4 5.3 0.03 13.4 0.4 2.2 2 0 0 2 2 2 2 Trypanosomal VSG domain NARP1 PF12569.3 EPE33969.1 - 2.6 6.7 9.8 4.9 5.7 6.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNase_H2-Ydr279 PF09468.5 EPE33969.1 - 9.3 5.3 7.2 1 8.5 1.6 1.8 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Abhydrolase_6 PF12697.2 EPE33970.1 - 2.2e-23 83.3 0.0 4e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE33970.1 - 1.9e-14 53.8 0.0 1.6e-11 44.1 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE33970.1 - 1.1e-06 28.5 0.0 3.7e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EPE33970.1 - 5.2e-05 21.8 0.0 8.1e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 EPE33970.1 - 0.00097 18.6 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase EthD PF07110.6 EPE33970.1 - 0.0017 19.2 0.5 2 9.3 0.2 3.4 2 2 0 2 2 2 2 EthD domain Lactonase PF10282.4 EPE33971.1 - 6e-17 61.7 0.0 8.9e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.16 EPE33972.1 - 2.5e-49 167.0 0.0 3.4e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EPE33972.1 - 8.9e-11 41.6 0.0 1.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Cna_B PF05738.8 EPE33972.1 - 0.0083 15.8 0.0 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 Cna protein B-type domain CarboxypepD_reg PF13620.1 EPE33972.1 - 0.014 15.4 0.0 0.18 11.8 0.0 2.7 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain Abhydrolase_3 PF07859.8 EPE33973.1 - 9.5e-45 152.7 0.0 2.1e-32 112.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE33973.1 - 0.0041 17.0 0.0 0.0077 16.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EPE33973.1 - 0.16 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Sugar_tr PF00083.19 EPE33974.1 - 8.6e-87 291.5 20.7 1e-86 291.3 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE33974.1 - 3.4e-24 85.2 27.2 1.2e-23 83.4 15.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE33974.1 - 1.6e-07 30.0 15.1 0.00062 18.2 3.2 2.6 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 EPE33974.1 - 6.1e-07 28.0 2.9 6.1e-07 28.0 2.0 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HeLo PF14479.1 EPE33975.1 - 5.4e-41 140.6 0.4 9.9e-41 139.8 0.2 1.5 2 0 0 2 2 2 1 Prion-inhibition and propagation AAA PF00004.24 EPE33975.1 - 4e-07 30.2 0.0 1.1e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 EPE33975.1 - 0.011 15.6 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Torsin Mg_chelatase PF01078.16 EPE33975.1 - 0.025 13.7 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EPE33975.1 - 0.031 14.0 0.1 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 EPE33975.1 - 0.036 14.0 0.1 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.12 EPE33975.1 - 0.05 13.0 0.1 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.1 EPE33975.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPE33975.1 - 0.14 13.0 0.1 3.3 8.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain Latarcin PF10279.4 EPE33975.1 - 1.1 9.5 3.3 1.5 9.0 0.2 2.7 3 0 0 3 3 3 0 Latarcin precursor F-box-like PF12937.2 EPE33976.1 - 2.8e-09 36.5 0.2 9.3e-09 34.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like Amidoligase_2 PF12224.3 EPE33977.1 - 0.0072 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme AAA_33 PF13671.1 EPE33977.1 - 0.024 14.4 0.1 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pyr_redox_3 PF13738.1 EPE33979.1 - 2.2e-24 86.6 0.0 1.2e-23 84.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE33979.1 - 2e-17 62.6 0.1 2.8e-14 52.2 0.1 2.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EPE33979.1 - 2.6e-12 46.5 0.1 1.1e-10 41.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPE33979.1 - 3.2e-08 32.9 0.2 1e-05 24.7 0.0 3.1 3 0 0 3 3 3 1 Thi4 family K_oxygenase PF13434.1 EPE33979.1 - 9.7e-08 31.2 0.1 3.3e-05 22.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPE33979.1 - 5e-07 29.7 0.0 0.09 12.6 0.1 3.2 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE33979.1 - 8e-06 24.9 1.3 0.00062 18.7 0.2 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPE33979.1 - 5.5e-05 23.4 0.3 0.28 11.6 0.0 3.4 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE33979.1 - 0.00026 20.0 0.1 0.0039 16.1 0.0 2.7 4 0 0 4 4 4 1 Lycopene cyclase protein Shikimate_DH PF01488.15 EPE33979.1 - 0.0023 18.0 0.0 0.14 12.2 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EPE33979.1 - 0.0066 15.3 0.6 0.44 9.3 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EPE33979.1 - 0.0093 15.0 0.3 0.028 13.5 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EPE33979.1 - 0.015 13.9 0.2 2.2 6.8 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.19 EPE33979.1 - 0.016 14.1 1.1 0.019 13.8 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 EPE33979.1 - 0.036 14.3 0.0 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EPE33979.1 - 0.11 12.3 0.7 4 7.1 0.1 3.3 4 0 0 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EPE33979.1 - 0.26 9.7 0.9 0.69 8.3 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein SET PF00856.23 EPE33980.1 - 1.9e-18 67.3 1.0 9.5e-18 65.0 0.0 2.8 2 2 0 2 2 2 1 SET domain BLIP PF07467.6 EPE33981.1 - 0.023 14.3 0.1 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase inhibitor (BLIP) Pil1 PF13805.1 EPE33982.1 - 2.9e-155 515.2 0.5 3.4e-155 515.0 0.3 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EPE33982.1 - 0.014 14.6 2.5 0.019 14.2 0.8 1.8 1 1 0 2 2 2 0 FAM92 protein BRAP2 PF07576.7 EPE33983.1 - 2e-22 78.8 0.0 3.5e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EPE33983.1 - 4.9e-16 58.6 6.7 1.3e-15 57.2 4.6 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EPE33983.1 - 2.6e-09 36.7 9.8 2.6e-09 36.7 6.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EPE33983.1 - 0.00016 21.2 8.0 0.00039 20.0 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE33983.1 - 0.00022 20.9 8.4 0.00022 20.9 5.8 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPE33983.1 - 0.00049 20.0 9.0 0.00049 20.0 6.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE33983.1 - 0.0021 17.7 7.4 0.0021 17.7 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE33983.1 - 0.0025 17.9 5.4 0.0025 17.9 3.7 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EPE33983.1 - 0.0049 16.5 5.4 0.014 15.0 2.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EPE33983.1 - 0.013 15.2 6.1 0.013 15.2 4.2 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EPE33983.1 - 0.34 10.7 8.6 0.019 14.7 1.8 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Baculo_RING PF05883.6 EPE33983.1 - 0.74 9.6 2.2 2.1 8.1 1.5 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FemAB PF02388.11 EPE33983.1 - 0.83 8.2 3.3 1.2 7.7 2.3 1.1 1 0 0 1 1 1 0 FemAB family zf-RING_4 PF14570.1 EPE33983.1 - 0.84 9.2 6.2 2.4 7.7 4.3 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ubiquitin PF00240.18 EPE33984.1 - 4.8e-136 442.3 23.5 1.1e-33 114.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EPE33984.1 - 2.2e-78 257.9 21.1 4.3e-19 67.9 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPE33984.1 - 2.6e-24 85.2 11.1 0.00015 21.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPE33984.1 - 5.2e-22 78.2 1.5 0.00071 19.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPE33984.1 - 5.2e-14 52.0 2.9 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPE33984.1 - 8.1e-14 51.5 2.4 0.13 12.5 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EPE33984.1 - 9.7e-11 41.5 0.0 1.5 8.8 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EPE33984.1 - 1.6e-06 27.9 5.8 4.5 7.2 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 EPE33984.1 - 5.3e-06 25.7 0.5 2 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 EPE33984.1 - 6.8e-05 22.5 5.3 14 5.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 EPE33984.1 - 0.00045 18.6 13.5 2.3 6.4 0.2 5.7 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 EPE33984.1 - 0.0011 18.4 0.0 48 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 EPE33984.1 - 0.0019 18.5 0.6 1e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 EPE33984.1 - 0.0055 16.7 5.2 53 4.0 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 EPE33984.1 - 0.023 14.5 14.3 7.9 6.4 0.2 4.4 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 EPE33984.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 EPE33984.1 - 0.037 14.0 7.8 44 4.1 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 EPE33984.1 - 0.071 13.1 12.4 42 4.2 0.1 5.9 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 EPE33984.1 - 0.4 10.6 7.4 1e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 EPE33984.1 - 1.8 8.2 8.3 1e+02 2.7 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 EPE33984.1 - 9.3 5.9 12.2 70 3.1 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 Zn_clus PF00172.13 EPE33985.1 - 0.004 17.0 7.8 0.0082 16.0 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAR9 PF08580.5 EPE33985.1 - 0.28 9.4 5.5 0.49 8.6 3.8 1.4 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Herpes_BMRF2 PF04633.7 EPE33985.1 - 0.32 9.9 0.3 0.54 9.1 0.0 1.4 2 0 0 2 2 2 0 Herpesvirus BMRF2 protein AT_hook PF02178.14 EPE33987.1 - 0.0017 17.8 0.6 2.5 8.0 0.0 3.9 2 0 0 2 2 2 2 AT hook motif PTCB-BRCT PF12738.2 EPE33987.1 - 0.0031 17.3 0.2 0.007 16.1 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain Acyltransferase PF01553.16 EPE33989.1 - 1.6e-10 40.5 0.0 2.3e-09 36.8 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase GrpB PF04229.9 EPE33993.1 - 2.3e-31 108.7 0.0 2.6e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Transp_cyt_pur PF02133.10 EPE33994.1 - 1.8e-100 336.5 40.4 2.1e-100 336.3 28.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PC_rep PF01851.17 EPE33995.1 - 5.7e-44 145.9 16.5 7.9e-09 35.2 0.0 9.7 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EPE33995.1 - 7.8e-19 67.7 0.2 1.3e-12 47.7 0.0 5.5 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 EPE33995.1 - 9.1e-10 37.7 0.0 3.2 8.0 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EPE33995.1 - 1e-07 32.1 1.2 0.00028 21.2 0.0 5.5 6 1 1 7 7 7 1 HEAT-like repeat TPR_19 PF14559.1 EPE33995.1 - 0.0035 17.6 4.2 1.2 9.5 0.2 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat HEAT_PBS PF03130.11 EPE33995.1 - 0.032 14.6 0.2 3.6 8.3 0.0 4.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Apc3 PF12895.2 EPE33995.1 - 0.057 13.5 0.8 5 7.3 0.1 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 IBN_N PF03810.14 EPE33995.1 - 0.076 12.9 0.0 52 3.8 0.0 3.9 3 1 1 4 4 4 0 Importin-beta N-terminal domain Sec62 PF03839.11 EPE33995.1 - 6.4 6.1 7.2 12 5.2 5.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 mRNA_triPase PF02940.10 EPE33996.1 - 1.4e-52 178.5 0.0 2.4e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Sugar_tr PF00083.19 EPE33997.1 - 1.5e-92 310.5 17.8 1.7e-92 310.3 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE33997.1 - 1.5e-40 139.0 28.1 4.1e-33 114.5 10.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE33997.1 - 2.2e-10 39.5 16.7 2e-08 33.0 1.0 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EPE33997.1 - 0.00042 18.6 4.3 0.0099 14.1 0.4 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EPE33997.1 - 0.00058 18.6 5.5 0.0038 15.9 1.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF791) Glyco_hydro_2_C PF02836.12 EPE33998.1 - 1.1e-99 333.0 0.0 1.5e-99 332.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EPE33998.1 - 2.5e-61 207.1 0.0 5e-61 206.1 0.0 1.5 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EPE33998.1 - 3e-29 101.6 0.0 8.4e-29 100.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EPE33998.1 - 5.2e-14 52.6 0.0 1.3e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Cellulase PF00150.13 EPE33999.1 - 1.1e-15 57.6 5.3 1.1e-15 57.6 3.7 1.9 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Acyl-CoA_dh_1 PF00441.19 EPE34000.1 - 4e-35 121.1 1.0 6.6e-35 120.4 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPE34000.1 - 3.3e-19 68.1 0.8 5.7e-19 67.3 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EPE34000.1 - 3.2e-13 50.0 0.1 5.5e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EPE34000.1 - 4.2e-07 30.5 0.1 5.5e-06 26.9 0.0 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 EPE34000.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Glyco_hydro_76 PF03663.9 EPE34002.1 - 6e-152 506.3 16.5 7.9e-152 505.9 11.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 FAD_binding_3 PF01494.14 EPE34003.1 - 3.5e-13 49.3 0.7 3.3e-12 46.1 0.5 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE34003.1 - 9.1e-06 24.8 0.1 0.012 14.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPE34003.1 - 6.2e-05 22.8 0.0 0.071 12.8 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EPE34003.1 - 0.00028 20.8 0.0 0.00066 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE34003.1 - 0.00037 19.5 0.0 0.062 12.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPE34003.1 - 0.0033 17.5 0.0 0.0087 16.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EPE34003.1 - 0.0098 14.7 0.0 0.088 11.6 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 EPE34003.1 - 0.054 13.3 1.1 0.055 13.3 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EPE34003.1 - 0.056 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 EPE34003.1 - 0.12 10.9 0.2 2.8 6.4 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.22 EPE34003.1 - 0.12 12.7 0.1 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 EPE34003.1 - 0.14 10.2 0.0 0.27 9.3 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) ADH_N PF08240.7 EPE34004.1 - 2e-21 75.8 1.8 3.9e-21 74.8 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE34004.1 - 1.9e-08 33.9 0.3 8.3e-07 28.6 0.0 3.1 3 1 0 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPE34004.1 - 0.00014 21.0 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EPE34004.1 - 0.011 15.2 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EPE34004.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F-box-like PF12937.2 EPE34005.1 - 0.014 15.0 0.4 0.029 14.0 0.2 1.5 1 0 0 1 1 1 0 F-box-like NACHT PF05729.7 EPE34009.1 - 2.1e-07 30.7 0.0 8.5e-07 28.7 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EPE34009.1 - 5.3e-07 29.8 0.0 1.6e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPE34009.1 - 0.00049 20.3 0.1 0.0057 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPE34009.1 - 0.001 19.8 0.1 0.01 16.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPE34009.1 - 0.0062 16.8 0.1 0.021 15.0 0.0 1.9 2 0 0 2 2 1 1 ABC transporter AAA_10 PF12846.2 EPE34009.1 - 0.0068 15.8 0.5 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EPE34009.1 - 0.0095 15.3 0.0 0.03 13.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPE34009.1 - 0.014 14.9 0.3 0.032 13.7 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EPE34009.1 - 0.015 15.4 0.1 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Ank PF00023.25 EPE34009.1 - 0.027 14.2 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 1 0 Ankyrin repeat AAA_16 PF13191.1 EPE34009.1 - 0.033 14.1 0.2 0.2 11.6 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.13 EPE34009.1 - 0.042 13.3 0.0 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 EPE34009.1 - 0.043 12.9 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ank_2 PF12796.2 EPE34009.1 - 0.046 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) MMR_HSR1 PF01926.18 EPE34009.1 - 0.06 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EPE34009.1 - 0.081 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EPE34009.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.1 EPE34009.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3196 PF11428.3 EPE34009.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) cobW PF02492.14 EPE34009.1 - 0.14 11.6 0.1 0.3 10.4 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EPE34009.1 - 0.16 10.6 0.0 0.37 9.5 0.0 1.5 1 0 0 1 1 1 0 ArgK protein A2M_recep PF07677.9 EPE34010.1 - 0.11 12.7 0.2 0.37 11.0 0.1 1.9 2 0 0 2 2 2 0 A-macroglobulin receptor Glyco_hydro_42M PF08532.5 EPE34011.1 - 0.039 13.1 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain 3Beta_HSD PF01073.14 EPE34012.1 - 9.4e-43 145.9 0.0 1.3e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE34012.1 - 1.5e-25 90.0 0.0 2.2e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Hemerythrin PF01814.18 EPE34012.1 - 3e-13 50.0 2.2 5.1e-13 49.3 1.5 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain RmlD_sub_bind PF04321.12 EPE34012.1 - 9e-13 47.7 0.0 1.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EPE34012.1 - 5.5e-10 38.5 0.1 9.4e-07 28.0 0.0 2.2 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EPE34012.1 - 7.5e-09 35.8 0.0 1.5e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPE34012.1 - 5.7e-06 26.3 0.1 1.7e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE34012.1 - 0.0001 22.0 0.0 0.00067 19.3 0.0 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPE34012.1 - 0.00029 19.8 0.6 0.00081 18.3 0.4 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 EPE34012.1 - 0.00059 19.7 0.1 0.0022 17.9 0.0 2.0 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus AstE_AspA PF04952.9 EPE34012.1 - 0.032 13.1 0.3 0.13 11.0 0.1 1.9 1 1 1 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family NmrA PF05368.8 EPE34012.1 - 0.047 12.9 0.1 0.084 12.1 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family DUF4013 PF13197.1 EPE34012.1 - 0.092 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) NAD_binding_3 PF03447.11 EPE34012.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF4328 PF14219.1 EPE34013.1 - 0.043 13.1 0.2 0.056 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) STT3 PF02516.9 EPE34013.1 - 0.057 12.3 0.2 0.072 12.0 0.2 1.1 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit YjgP_YjgQ PF03739.9 EPE34013.1 - 0.077 11.7 1.0 0.098 11.3 0.7 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Tad PF13400.1 EPE34013.1 - 0.13 12.2 0.8 0.18 11.8 0.0 1.5 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF1275 PF06912.6 EPE34013.1 - 0.16 11.1 0.3 0.2 10.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) TadE PF07811.7 EPE34013.1 - 0.44 10.4 2.1 0.8 9.6 0.1 2.0 2 0 0 2 2 2 0 TadE-like protein RCR PF12273.3 EPE34013.1 - 5.2 7.6 6.3 1.4 9.4 1.8 1.9 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red p450 PF00067.17 EPE34014.1 - 6.6e-51 173.2 0.0 4.3e-36 124.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Yip1 PF04893.12 EPE34015.1 - 1.4e-07 31.1 12.9 1.8e-07 30.7 8.3 1.6 1 1 0 1 1 1 1 Yip1 domain Pex24p PF06398.6 EPE34016.1 - 2e-96 322.9 0.1 2.5e-96 322.6 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF1426 PF07234.6 EPE34016.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) Ribosomal_S9 PF00380.14 EPE34018.1 - 1.7e-34 118.6 0.4 2.6e-34 118.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF-hand_1 PF00036.27 EPE34020.1 - 2.7e-26 88.8 12.2 8.8e-07 27.7 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EPE34020.1 - 9.7e-24 83.2 3.1 1.3e-12 47.6 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EPE34020.1 - 2.1e-20 70.6 5.0 4.7e-05 22.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EPE34020.1 - 7.4e-19 66.1 11.9 2.4e-06 26.6 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EPE34020.1 - 3.1e-15 55.5 12.7 1.9e-05 24.1 0.7 4.6 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EPE34020.1 - 7e-07 29.2 0.0 0.00062 19.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EPE34020.1 - 1.1e-06 28.2 7.2 0.0028 17.3 0.3 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EPE34020.1 - 0.08 12.8 0.1 1.9 8.4 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain EPL1 PF10513.4 EPE34021.1 - 4.5e-30 105.0 12.7 1.4e-29 103.4 3.5 2.6 2 1 0 2 2 2 2 Enhancer of polycomb-like Rubis-subs-bind PF09273.6 EPE34022.1 - 5.5e-20 71.5 2.1 1.1e-19 70.6 1.4 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EPE34022.1 - 1e-15 58.4 0.2 7.2e-14 52.4 0.0 2.7 2 1 0 2 2 2 1 SET domain PHD PF00628.24 EPE34023.1 - 8.4e-16 57.3 20.7 7.3e-11 41.5 6.7 2.7 2 1 1 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 EPE34023.1 - 0.016 14.4 6.3 0.61 9.3 1.3 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EPE34023.1 - 0.095 12.0 15.5 0.096 12.0 3.4 3.4 3 0 0 3 3 3 0 PHD-finger zf-HC5HC2H PF13771.1 EPE34023.1 - 0.35 11.0 9.4 0.082 13.0 2.0 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain Peptidase_M22 PF00814.20 EPE34024.1 - 8.2e-83 277.9 0.0 1e-82 277.6 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family PRA1 PF03208.14 EPE34025.1 - 0.0013 18.0 6.3 0.0017 17.7 4.4 1.1 1 0 0 1 1 1 1 PRA1 family protein CstA PF02554.9 EPE34025.1 - 0.024 13.3 2.3 0.028 13.0 1.6 1.1 1 0 0 1 1 1 0 Carbon starvation protein CstA Form-deh_trans PF09163.6 EPE34025.1 - 0.43 10.0 1.9 1.1 8.7 1.3 1.7 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane AMPKBI PF04739.10 EPE34026.1 - 1.5e-30 104.9 0.1 1.5e-30 104.9 0.1 2.3 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain p450 PF00067.17 EPE34027.1 - 2.1e-24 85.9 0.0 8.3e-19 67.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Phytoreo_Pns PF05451.6 EPE34027.1 - 0.1 11.2 0.2 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 Ham1p_like PF01725.11 EPE34028.1 - 1.9e-53 180.6 0.0 2.2e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 EPE34029.1 - 4e-28 98.2 0.1 4e-28 98.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPE34029.1 - 3.1e-15 57.0 1.7 6.8e-15 55.9 0.1 1.8 1 1 1 2 2 2 1 AAA domain ADK PF00406.17 EPE34029.1 - 1.1e-06 28.6 0.0 0.00017 21.4 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase SKI PF01202.17 EPE34029.1 - 7.7e-06 25.8 0.3 3.4e-05 23.7 0.2 1.8 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 EPE34029.1 - 1.2e-05 25.2 0.1 0.00019 21.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPE34029.1 - 9.4e-05 22.4 0.3 0.00023 21.1 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EPE34029.1 - 0.00012 22.3 0.0 0.0003 20.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EPE34029.1 - 0.00032 20.4 0.0 0.00073 19.2 0.0 1.7 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.1 EPE34029.1 - 0.0018 18.4 0.1 0.0025 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EPE34029.1 - 0.0032 16.8 0.2 0.85 8.9 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase Cytidylate_kin2 PF13189.1 EPE34029.1 - 0.0065 16.3 0.1 0.032 14.1 0.0 2.2 1 1 1 2 2 2 1 Cytidylate kinase-like family KTI12 PF08433.5 EPE34029.1 - 0.0075 15.5 0.1 0.021 14.0 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_14 PF13173.1 EPE34029.1 - 0.0091 15.8 0.0 0.03 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPE34029.1 - 0.021 14.5 0.2 0.051 13.2 0.1 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EPE34029.1 - 0.026 14.4 0.0 0.065 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EPE34029.1 - 0.035 13.5 1.1 0.097 12.0 0.0 2.0 2 1 0 2 2 2 0 AAA-like domain RuvB_N PF05496.7 EPE34029.1 - 0.039 12.9 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EPE34029.1 - 0.045 13.9 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EPE34029.1 - 0.048 13.0 0.1 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.10 EPE34029.1 - 0.05 12.2 0.0 0.072 11.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EPE34029.1 - 0.072 12.6 0.1 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EPE34029.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 EPE34029.1 - 0.095 11.4 0.0 0.14 10.8 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 EPE34029.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_3 PF07726.6 EPE34029.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EPE34029.1 - 0.14 11.6 0.1 0.31 10.4 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRP54 PF00448.17 EPE34029.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 EPE34029.1 - 0.15 11.5 0.5 0.24 10.9 0.1 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 EPE34029.1 - 0.2 10.5 0.1 0.2 10.5 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_11 PF13086.1 EPE34029.1 - 0.2 11.1 1.9 8.2 5.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain Dna2 PF08696.6 EPE34029.1 - 0.24 10.6 3.1 0.13 11.5 0.7 1.6 2 0 0 2 2 2 0 DNA replication factor Dna2 ArsA_ATPase PF02374.10 EPE34029.1 - 8.3 5.3 6.9 15 4.5 0.3 2.7 2 1 1 3 3 3 0 Anion-transporting ATPase Myosin_head PF00063.16 EPE34030.1 - 8.3e-242 804.1 0.6 8.3e-242 804.1 0.4 1.8 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.14 EPE34030.1 - 1.8e-34 117.7 5.0 2.9e-34 117.0 2.3 2.3 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 EPE34030.1 - 2.4e-10 39.0 45.4 0.00016 21.0 1.4 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 EPE34030.1 - 0.0014 18.8 0.1 0.012 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.14 EPE34030.1 - 0.0025 17.4 0.7 0.0073 15.9 0.5 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.1 EPE34030.1 - 0.0033 17.4 0.8 0.038 13.9 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EPE34030.1 - 0.005 16.5 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain zf-C4H2 PF10146.4 EPE34030.1 - 0.0057 16.7 7.3 0.015 15.2 5.0 1.7 1 0 0 1 1 1 1 Zinc finger-containing protein Myosin_tail_1 PF01576.14 EPE34030.1 - 0.0068 14.1 30.7 0.083 10.6 4.1 2.0 1 1 1 2 2 2 2 Myosin tail TMP_2 PF06791.8 EPE34030.1 - 0.011 15.3 3.9 0.027 14.0 2.7 1.6 1 0 0 1 1 1 0 Prophage tail length tape measure protein APG6 PF04111.7 EPE34030.1 - 0.15 11.0 30.8 0.084 11.9 16.5 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 EPE34030.1 - 0.79 9.4 26.5 0.45 10.2 10.1 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CCDC155 PF14662.1 EPE34030.1 - 0.82 9.2 30.5 0.027 14.0 4.4 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 M_domain PF12938.2 EPE34030.1 - 1.9 8.2 10.1 5.8 6.6 0.9 2.5 2 0 0 2 2 2 0 M domain of GW182 FlaC_arch PF05377.6 EPE34030.1 - 2.1 8.2 17.5 0.088 12.7 0.4 4.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) EMP24_GP25L PF01105.19 EPE34030.1 - 2.8 7.6 13.0 1.2e+02 2.2 8.5 2.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD GAS PF13851.1 EPE34030.1 - 4.5 6.4 33.9 19 4.3 20.5 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 EPE34030.1 - 5.8 7.0 14.2 3 7.9 6.7 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 EPE34030.1 - 6 7.2 26.1 1.5 9.1 3.0 3.6 3 0 0 3 3 3 0 Snapin/Pallidin 2-Hacid_dh_C PF02826.14 EPE34031.1 - 4.9e-49 165.8 0.0 7.6e-49 165.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPE34031.1 - 5.2e-34 116.5 0.0 6.9e-34 116.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPE34031.1 - 1.7e-05 24.7 0.2 3.7e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EPE34031.1 - 0.0017 17.7 0.3 0.026 13.9 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 EPE34031.1 - 0.0032 16.9 0.3 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.16 EPE34031.1 - 0.004 17.0 0.4 0.0084 15.9 0.1 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 EPE34031.1 - 0.03 13.9 0.1 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAP PF00956.13 EPE34032.1 - 6.4e-89 297.2 8.5 6.4e-89 297.2 5.9 2.1 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) HAD PF12710.2 EPE34033.1 - 2.4e-32 112.6 0.0 8.2e-32 110.9 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EPE34033.1 - 4.9e-25 87.9 0.0 1.1e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.3 EPE34033.1 - 2.7e-19 69.1 1.4 2.9e-12 46.4 1.4 2.8 1 1 1 2 2 2 2 P5-type ATPase cation transporter Hydrolase PF00702.21 EPE34033.1 - 2.6e-16 60.7 0.0 6.7e-15 56.0 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPE34033.1 - 0.0035 16.7 0.0 0.0079 15.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EPE34033.1 - 0.0055 16.6 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPE34033.1 - 0.014 14.9 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase CMAS PF02353.15 EPE34034.1 - 3.1e-39 134.6 1.0 4.6e-39 134.1 0.7 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EPE34034.1 - 2.9e-16 59.4 0.0 4.1e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE34034.1 - 5.6e-16 58.8 0.0 9.2e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE34034.1 - 6e-14 52.0 0.0 9.3e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE34034.1 - 6.8e-12 45.9 0.0 1.8e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE34034.1 - 1.5e-11 44.6 0.0 2.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE34034.1 - 2.5e-09 37.4 0.0 4.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE34034.1 - 5.6e-08 32.1 0.0 8.4e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EPE34034.1 - 7.8e-08 31.8 0.0 1.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EPE34034.1 - 0.00029 20.4 0.0 0.00062 19.3 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EPE34034.1 - 0.00082 18.4 0.0 0.0025 16.9 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase DUF938 PF06080.7 EPE34034.1 - 0.0026 17.3 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 EPE34034.1 - 0.0051 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EPE34034.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB GidB PF02527.10 EPE34034.1 - 0.041 13.0 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RrnaAD PF00398.15 EPE34034.1 - 0.059 12.3 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ApoB100_C PF12491.3 EPE34035.1 - 0.042 13.4 0.5 1.4 8.5 0.0 2.2 1 1 1 2 2 2 0 Apolipoprotein B100 C terminal AAA_13 PF13166.1 EPE34035.1 - 0.056 11.8 1.4 0.065 11.6 1.0 1.0 1 0 0 1 1 1 0 AAA domain DUF515 PF04415.7 EPE34035.1 - 0.13 10.4 0.3 0.14 10.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) 4HB_MCP_1 PF12729.2 EPE34035.1 - 0.17 11.1 4.4 0.2 10.9 2.1 1.6 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction ASD1 PF08688.5 EPE34035.1 - 0.53 10.0 2.9 0.71 9.6 2.0 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 NADH_B2 PF14813.1 EPE34037.1 - 0.0038 16.8 0.1 0.0042 16.7 0.1 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.20 EPE34038.1 - 2.4e-64 216.9 0.0 2.9e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE34038.1 - 2.9e-28 98.6 0.0 4e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE34038.1 - 0.00089 18.2 0.0 0.0025 16.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Peptidase_C78 PF07910.8 EPE34039.1 - 4.4e-62 209.0 0.0 5.9e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-H2C2_5 PF13909.1 EPE34039.1 - 0.00016 21.7 0.3 0.00071 19.6 0.1 2.3 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-Di19 PF05605.7 EPE34039.1 - 0.005 16.9 2.0 0.026 14.6 0.1 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-RAG1 PF10426.4 EPE34039.1 - 0.02 14.8 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain zf-TRAF PF02176.13 EPE34039.1 - 0.061 13.7 0.2 0.77 10.1 0.0 2.5 2 0 0 2 2 2 0 TRAF-type zinc finger tRNA-synt_2b PF00587.20 EPE34040.1 - 7e-36 123.3 0.0 1e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EPE34040.1 - 3.2e-19 68.9 5.9 3.2e-19 68.9 4.1 1.9 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 EPE34040.1 - 0.011 15.4 4.0 0.03 14.0 2.8 1.7 1 0 0 1 1 1 0 Mnd1 family NPIP PF06409.6 EPE34040.1 - 0.11 11.1 2.7 0.18 10.5 1.9 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Ras PF00071.17 EPE34041.1 - 1.7e-46 157.5 0.8 2e-46 157.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE34041.1 - 8.6e-16 58.5 0.2 1.2e-15 58.0 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE34041.1 - 4.7e-08 32.4 0.0 5e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPE34041.1 - 3.1e-07 29.9 0.4 7.6e-06 25.4 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPE34041.1 - 3.9e-06 26.8 0.1 5.4e-06 26.3 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPE34041.1 - 0.00012 21.3 0.0 0.00023 20.4 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EPE34041.1 - 0.0088 16.0 0.1 0.065 13.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 EPE34041.1 - 0.043 13.1 0.0 0.22 10.7 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.1 EPE34041.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain WAPL PF07814.8 EPE34042.1 - 1e-18 67.2 0.3 1.9e-18 66.3 0.1 1.5 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin DUF4142 PF13628.1 EPE34042.1 - 0.039 13.9 0.0 0.56 10.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) UPRTase PF14681.1 EPE34043.1 - 4.7e-79 264.3 0.0 6.3e-79 263.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EPE34043.1 - 0.00055 19.6 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EPE34043.1 - 0.045 13.4 0.1 0.068 12.9 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 EPE34044.1 - 1e-28 98.8 3.3 1.3e-28 98.5 2.3 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like UPF0515 PF15135.1 EPE34044.1 - 0.012 14.7 0.6 0.018 14.1 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 zf-CHY PF05495.7 EPE34044.1 - 0.029 14.5 1.5 0.041 14.0 1.0 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-C2H2_6 PF13912.1 EPE34044.1 - 2.1 8.3 5.6 0.68 9.9 1.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger GTP_CH_N PF12471.3 EPE34045.1 - 1.1e-91 305.7 0.0 1.6e-91 305.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EPE34045.1 - 5.2e-17 61.6 0.1 1.5e-16 60.1 0.0 1.7 2 0 0 2 2 2 1 GTP cyclohydrolase II Ribosomal_S3Ae PF01015.13 EPE34047.1 - 1.8e-82 275.3 5.8 2.2e-82 275.1 4.0 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 EPE34047.1 - 0.055 13.6 1.7 0.11 12.6 0.3 2.1 2 0 0 2 2 2 0 Syntaxin Ras PF00071.17 EPE34048.1 - 9.5e-51 171.3 0.0 1.1e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE34048.1 - 7.4e-15 55.4 0.0 9.4e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE34048.1 - 2e-13 49.9 0.0 2.5e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPE34048.1 - 2.9e-07 30.1 0.0 6.4e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPE34048.1 - 5.8e-07 28.8 0.0 6.6e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPE34048.1 - 0.00022 21.1 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPE34048.1 - 0.0077 15.4 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EPE34048.1 - 0.0079 16.0 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EPE34048.1 - 0.011 15.1 0.1 0.026 14.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EPE34048.1 - 0.035 14.2 0.0 0.11 12.6 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EPE34048.1 - 0.036 13.5 0.0 0.067 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EPE34048.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EPE34048.1 - 0.14 13.0 0.1 0.21 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.2 EPE34049.1 - 6.3e-33 114.5 0.0 1.1e-32 113.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE34049.1 - 3.6e-19 69.2 1.6 5.9e-18 65.2 0.4 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE34049.1 - 1.5e-16 60.4 0.0 4e-16 59.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPE34049.1 - 6.3e-09 35.7 0.0 9.9e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 EPE34049.1 - 7.2e-06 25.7 0.1 1.3e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EPE34049.1 - 1.9e-05 24.9 0.0 2.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 EPE34049.1 - 0.00026 20.5 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 EPE34049.1 - 0.023 14.2 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 EPE34049.1 - 0.038 13.2 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ndr PF03096.9 EPE34049.1 - 0.067 11.6 0.0 0.14 10.6 0.0 1.4 2 0 0 2 2 2 0 Ndr family Lipase_3 PF01764.20 EPE34049.1 - 0.073 12.6 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 EPE34049.1 - 0.079 12.3 0.0 9.2 5.6 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Gly_transf_sug PF04488.10 EPE34050.1 - 4.4e-20 71.9 0.1 8.5e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EPE34050.1 - 0.0077 14.7 8.5 0.29 9.5 0.5 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Peptidase_C97 PF05903.9 EPE34051.1 - 1.1e-05 25.1 0.0 5.3e-05 23.0 0.0 1.9 1 1 1 2 2 2 1 PPPDE putative peptidase domain LRAT PF04970.8 EPE34051.1 - 0.025 14.5 0.8 0.25 11.2 0.5 2.2 1 1 0 1 1 1 0 Lecithin retinol acyltransferase DUF4105 PF13387.1 EPE34051.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Fork_head PF00250.13 EPE34052.1 - 1.3e-33 114.8 0.1 2.4e-33 114.0 0.1 1.4 1 0 0 1 1 1 1 Fork head domain Mid1 PF12929.2 EPE34054.1 - 1.7e-115 386.1 1.7 2e-115 385.9 1.2 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EPE34054.1 - 1.8 8.9 7.3 49 4.3 3.7 3.0 2 1 1 3 3 3 0 Fz domain TB2_DP1_HVA22 PF03134.14 EPE34055.1 - 8.7e-31 105.5 6.5 1.2e-30 105.0 4.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PSI_PsaE PF02427.12 EPE34055.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE RFX_DNA_binding PF02257.10 EPE34056.1 - 3.9e-29 100.6 0.1 1.1e-28 99.2 0.0 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain AA_kinase PF00696.23 EPE34057.1 - 3.3e-36 125.0 0.1 6.1e-36 124.1 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EPE34057.1 - 2.4e-14 52.4 0.9 3e-08 32.9 0.0 3.0 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EPE34057.1 - 1.1e-11 44.0 4.3 5.7e-09 35.3 0.2 2.5 2 0 0 2 2 2 2 ACT domain RRM_2 PF04059.7 EPE34058.1 - 4e-39 132.4 0.2 6.9e-39 131.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EPE34058.1 - 0.00025 20.6 0.1 0.031 13.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE34058.1 - 0.00033 20.5 0.2 0.0095 15.9 0.1 3.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Synthase_beta PF11421.3 EPE34058.1 - 0.026 15.1 3.3 0.026 15.1 2.3 2.9 2 0 0 2 2 2 0 ATP synthase F1 beta subunit Nha1_C PF08619.5 EPE34058.1 - 0.042 13.1 1.4 0.071 12.3 0.9 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus RRM_5 PF13893.1 EPE34058.1 - 0.067 13.0 0.0 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.7 EPE34059.1 - 3.7e-86 289.2 0.2 3.7e-86 289.2 0.1 2.6 2 2 1 3 3 3 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 EPE34059.1 - 0.0011 18.4 7.1 0.0031 16.9 4.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) COG5 PF10392.4 EPE34059.1 - 0.035 14.0 5.0 0.04 13.8 2.0 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 EPE34059.1 - 0.62 9.6 15.1 0.013 15.1 3.5 3.4 4 1 0 4 4 4 0 Sec8 exocyst complex component specific domain COG2 PF06148.6 EPE34059.1 - 1.8 8.4 12.0 0.036 13.9 2.0 2.9 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 CBFD_NFYB_HMF PF00808.18 EPE34060.1 - 5.5e-20 71.1 0.4 1e-19 70.3 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPE34060.1 - 4.7e-11 42.6 0.1 8.5e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EPE34060.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X PAT1 PF09770.4 EPE34060.1 - 0.077 11.2 17.4 0.098 10.8 12.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fcf2 PF08698.6 EPE34062.1 - 6.4e-34 115.9 0.6 1.4e-33 114.8 0.4 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing tRNA-synt_1b PF00579.20 EPE34063.1 - 4.1e-68 229.6 0.0 5.5e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.17 EPE34063.1 - 3.5e-25 87.6 0.0 2.9e-24 84.7 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Spt4 PF06093.8 EPE34064.1 - 1.2e-31 108.4 0.1 1.5e-31 108.0 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.6 EPE34064.1 - 0.08 12.7 0.1 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Coronavirus gene 5 protein Kin17_mid PF10357.4 EPE34065.1 - 7.7e-52 174.2 0.5 1.6e-51 173.1 0.4 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EPE34065.1 - 0.0002 21.4 0.7 0.00039 20.4 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPE34065.1 - 0.00029 20.9 1.3 0.00064 19.8 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EPE34065.1 - 0.0074 16.3 3.6 0.0084 16.2 0.1 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) GHMP_kinases_N PF00288.21 EPE34066.1 - 2.3e-14 53.1 0.2 4.5e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPE34066.1 - 0.0067 16.6 0.1 0.061 13.5 0.1 2.2 1 1 1 2 2 2 1 GHMP kinases C terminal GARS_A PF01071.14 EPE34067.1 - 7.3e-84 280.1 0.2 2.3e-83 278.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EPE34067.1 - 1e-33 115.7 0.0 6.9e-33 113.1 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EPE34067.1 - 1.6e-31 109.3 0.0 3.6e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EPE34067.1 - 3.4e-27 94.4 0.3 9.5e-27 93.0 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EPE34067.1 - 8.7e-17 61.1 2.4 4.1e-16 59.0 1.5 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EPE34067.1 - 1.5e-12 47.6 0.0 4e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPE34067.1 - 2.5e-07 29.7 0.0 4.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EPE34067.1 - 8.6e-07 28.4 0.0 1.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EPE34067.1 - 0.00037 19.8 0.0 0.00082 18.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EPE34067.1 - 0.0033 17.3 0.0 0.0094 15.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 EPE34067.1 - 0.0039 16.6 0.1 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 EPE34067.1 - 0.012 14.9 0.0 0.041 13.2 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EPE34067.1 - 0.095 12.0 0.0 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus SOR_SNZ PF01680.12 EPE34068.1 - 1.7e-113 377.3 7.1 2.8e-113 376.6 4.9 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EPE34068.1 - 8.5e-09 34.8 5.0 3.2e-06 26.3 0.1 2.5 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EPE34068.1 - 0.0046 16.2 1.1 0.18 11.0 0.0 2.7 2 1 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.12 EPE34068.1 - 0.0072 15.1 0.5 0.24 10.2 0.0 2.3 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) IGPS PF00218.16 EPE34068.1 - 0.0099 14.9 0.3 0.089 11.8 0.0 2.3 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EPE34068.1 - 0.02 13.8 1.1 0.16 10.9 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 EPE34068.1 - 0.029 13.5 2.6 0.046 12.8 0.1 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase FUN14 PF04930.10 EPE34069.1 - 1.9e-09 37.6 2.8 1.1e-08 35.2 1.9 2.0 1 1 0 1 1 1 1 FUN14 family Peptidase_M24 PF00557.19 EPE34070.1 - 3.2e-42 144.4 0.0 4.8e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EPE34070.1 - 2.5e-22 79.8 0.0 3.5e-19 69.5 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Xpo1 PF08389.7 EPE34071.1 - 2.1e-08 34.1 9.6 5.8e-08 32.7 0.2 4.9 4 1 1 5 5 5 1 Exportin 1-like protein Urb2 PF10441.4 EPE34071.1 - 0.00076 19.1 0.2 0.62 9.6 0.0 2.7 2 0 0 2 2 2 2 Urb2/Npa2 family BDHCT PF08072.6 EPE34071.1 - 0.04 14.0 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 BDHCT (NUC031) domain Sad1_UNC PF07738.8 EPE34072.1 - 6.8e-35 119.8 0.2 1.2e-34 118.9 0.2 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ARD PF03079.9 EPE34073.1 - 2.4e-47 160.7 0.3 2.8e-47 160.5 0.2 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EPE34073.1 - 4.4e-08 32.5 0.1 7.2e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EPE34073.1 - 0.00023 20.8 0.1 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EPE34073.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF1510 PF07423.6 EPE34074.1 - 0.011 15.0 0.2 0.016 14.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SOG2 PF10428.4 EPE34074.1 - 4 5.9 18.9 4.5 5.8 13.1 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2217 PF10265.4 EPE34074.1 - 5 5.7 8.8 5.9 5.5 6.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Apt1 PF10351.4 EPE34074.1 - 9.6 4.9 10.3 12 4.5 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain adh_short PF00106.20 EPE34075.1 - 8.7e-23 81.0 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE34075.1 - 1.1e-11 44.7 0.0 1.7e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE34075.1 - 1.5e-07 31.4 0.0 2.2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPE34075.1 - 2.9e-07 30.1 0.1 5e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE34075.1 - 0.00058 19.9 0.0 0.001 19.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPE34075.1 - 0.0008 18.3 0.0 0.001 18.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EPE34075.1 - 0.0013 17.6 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EPE34075.1 - 0.0093 14.6 0.1 0.013 14.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EPE34075.1 - 0.011 15.0 0.0 0.031 13.5 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family NAD_binding_4 PF07993.7 EPE34075.1 - 0.14 11.0 0.0 25 3.6 0.0 2.8 2 1 1 3 3 3 0 Male sterility protein DER1 PF04511.10 EPE34076.1 - 3e-49 167.2 4.5 3.4e-49 167.0 3.1 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.19 EPE34077.1 - 2.5e-29 101.1 0.2 3.5e-29 100.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T PF15511.1 EPE34077.1 - 0.00038 19.8 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EPE34077.1 - 0.00094 19.3 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPE34077.1 - 0.032 14.3 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2404 PF10296.4 EPE34078.1 - 7.5e-09 35.6 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) UAA PF08449.6 EPE34079.1 - 2.6e-10 39.6 13.2 3.7e-10 39.2 9.1 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EPE34079.1 - 5.4e-09 35.8 10.0 5.4e-09 35.8 7.0 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EPE34079.1 - 0.00049 20.1 25.9 0.00066 19.7 6.3 2.4 2 1 0 2 2 2 2 EamA-like transporter family Peptidase_A24 PF01478.13 EPE34079.1 - 0.23 11.6 0.1 0.23 11.6 0.1 3.5 2 2 1 3 3 3 0 Type IV leader peptidase family Thioredoxin PF00085.15 EPE34080.1 - 5.1e-05 22.8 0.0 9.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Xan_ur_permease PF00860.15 EPE34081.1 - 4.9e-29 101.0 29.5 1e-28 99.9 18.0 2.6 2 1 0 2 2 2 1 Permease family Mem_trans PF03547.13 EPE34081.1 - 4.4 5.5 10.3 1.5 7.0 1.5 2.4 2 0 0 2 2 2 0 Membrane transport protein RRM_1 PF00076.17 EPE34082.1 - 9.3e-07 28.4 0.0 1.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE34082.1 - 3.8e-06 26.6 0.0 7.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE34082.1 - 0.00011 22.0 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPE34082.1 - 0.0054 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EPE34082.1 - 0.018 14.7 0.7 0.033 13.8 0.5 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UreF PF01730.11 EPE34083.1 - 1.5e-12 47.8 0.0 2.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 UreF DASH_Spc34 PF08657.5 EPE34083.1 - 0.11 12.2 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 MARVEL PF01284.18 EPE34084.1 - 4.1e-21 75.2 6.0 5.1e-21 74.9 4.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain Tetraspannin PF00335.15 EPE34084.1 - 0.00018 20.8 1.3 0.00018 20.8 0.9 1.6 1 1 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.4 EPE34084.1 - 0.25 9.9 1.0 2.5 6.6 0.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.3 EPE34084.1 - 0.51 9.9 0.0 0.51 9.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) eRF1_2 PF03464.10 EPE34085.1 - 5.6e-47 159.3 0.1 1e-46 158.5 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EPE34085.1 - 3.6e-39 133.5 0.4 7.5e-39 132.4 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EPE34085.1 - 3.2e-28 97.9 0.0 5.8e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 DUF1770 PF08589.5 EPE34086.1 - 1.3e-26 93.1 1.0 1.6e-26 92.7 0.7 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) RE_Bsp6I PF09504.5 EPE34087.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Bsp6I restriction endonuclease WHIM1 PF15612.1 EPE34087.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Ribosomal_L2_C PF03947.13 EPE34088.1 - 5.6e-38 129.6 3.7 5.6e-38 129.6 2.5 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPE34088.1 - 4.7e-14 52.1 0.0 9.7e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.19 EPE34089.1 - 6.6e-64 215.9 0.2 7.4e-64 215.7 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EPE34089.1 - 0.00043 19.5 0.0 0.00087 18.5 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.4 EPE34090.1 - 8.3e-53 179.3 0.0 1.3e-52 178.7 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EPE34090.1 - 1.9e-17 63.4 1.3 4.9e-17 62.1 0.9 1.7 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EPE34090.1 - 3.1e-06 26.7 0.4 9e-06 25.2 0.3 1.7 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.1 EPE34090.1 - 0.11 12.7 0.2 0.32 11.3 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C2H2_jaz PF12171.3 EPE34091.1 - 0.3 11.3 0.2 0.3 11.3 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EPE34091.1 - 0.55 10.6 12.3 2 8.9 0.8 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE34091.1 - 3.7 8.0 12.1 19 5.8 1.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1649 PF07855.7 EPE34092.1 - 1.1e-59 200.7 0.2 1.3e-59 200.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Peroxin-3 PF04882.7 EPE34093.1 - 2.9e-148 494.1 0.0 3.4e-148 493.9 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Sybindin PF04099.7 EPE34094.1 - 2.7e-27 95.2 0.0 3.3e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EPE34094.1 - 0.011 15.5 0.1 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Pkinase PF00069.20 EPE34095.1 - 2.1e-58 197.5 0.0 4.8e-58 196.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE34095.1 - 4.5e-32 111.1 0.0 3e-30 105.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPE34095.1 - 2.5e-07 29.9 0.0 8.1e-06 25.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPE34095.1 - 0.0027 17.5 0.1 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family G10 PF01125.12 EPE34096.1 - 2e-36 124.7 0.1 2.4e-36 124.4 0.1 1.0 1 0 0 1 1 1 1 G10 protein SNase PF00565.12 EPE34096.1 - 0.094 12.9 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Staphylococcal nuclease homologue Complex1_LYR_2 PF13233.1 EPE34097.1 - 5.3e-06 26.8 0.2 7.3e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EPE34097.1 - 0.00018 21.2 0.3 0.00041 20.0 0.2 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPE34097.1 - 0.0072 16.5 0.4 0.012 15.8 0.2 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Vps51 PF08700.6 EPE34097.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Vps51/Vps67 RNA_pol_L_2 PF13656.1 EPE34098.1 - 2.5e-31 106.9 0.0 3.7e-31 106.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EPE34098.1 - 2.1e-11 42.7 0.0 2.9e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.20 EPE34100.1 - 5.3e-64 215.8 0.0 8e-64 215.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE34100.1 - 4.3e-27 94.8 0.0 8.3e-27 93.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPE34100.1 - 0.0096 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPE34100.1 - 0.027 13.4 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EPE34100.1 - 0.078 12.3 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Phosphodiest PF01663.17 EPE34102.1 - 2.1e-18 66.8 0.7 3.9e-17 62.6 0.5 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2423 PF10338.4 EPE34102.1 - 4e-15 55.5 1.2 4e-15 55.5 0.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Sulfatase PF00884.18 EPE34102.1 - 8.7e-06 25.1 0.0 3.7e-05 23.0 0.0 2.0 3 0 0 3 3 3 1 Sulfatase Metalloenzyme PF01676.13 EPE34102.1 - 0.00081 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily PINIT PF14324.1 EPE34103.1 - 1.3e-35 122.5 0.0 2.6e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EPE34103.1 - 5.8e-21 73.7 5.8 1e-20 72.9 4.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EPE34103.1 - 5.3e-05 22.6 1.2 0.00012 21.5 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 EPE34103.1 - 0.053 13.0 0.1 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C3HC4_4 PF15227.1 EPE34103.1 - 0.62 9.9 4.2 1.2 9.1 2.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING 6PF2K PF01591.13 EPE34104.1 - 1.4e-60 204.1 0.0 1.9e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPE34104.1 - 7.7e-21 74.8 0.2 1.3e-20 74.1 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EPE34104.1 - 0.0012 19.6 0.4 0.0062 17.3 0.0 2.4 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EPE34104.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EPE34104.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Porin_3 PF01459.17 EPE34105.1 - 2.4e-85 286.1 0.2 2.8e-85 285.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF4096 PF13340.1 EPE34106.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) Pkinase PF00069.20 EPE34107.1 - 2.2e-63 213.8 0.0 2.6e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE34107.1 - 1.2e-25 90.0 0.0 1.6e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE34107.1 - 2.4e-07 30.0 0.0 1.1e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPE34107.1 - 0.0012 18.6 0.0 0.0056 16.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE34107.1 - 0.035 13.6 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 EPE34108.1 - 5.2e-84 280.4 0.0 1.2e-83 279.2 0.0 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EPE34108.1 - 1.4e-50 171.9 0.1 1.2e-49 168.8 0.0 2.3 2 1 1 3 3 3 1 MIF4G like MIF4G PF02854.14 EPE34108.1 - 0.001 18.5 0.0 0.0036 16.7 0.0 1.9 2 0 0 2 2 2 1 MIF4G domain RRM_1 PF00076.17 EPE34109.1 - 1.6e-32 110.9 0.0 4e-15 55.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE34109.1 - 2.2e-18 66.0 0.0 3e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE34109.1 - 6.1e-15 54.8 0.0 6.2e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EPE34109.1 - 0.0022 17.4 0.3 0.17 11.4 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 EPE34109.1 - 0.022 14.4 0.1 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 Mito_carr PF00153.22 EPE34110.1 - 1.5e-52 175.3 5.0 2.1e-21 75.4 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.7 EPE34110.1 - 6.9e-18 63.8 0.1 1.3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 TOM7 family PsbJ PF01788.12 EPE34110.1 - 0.14 11.7 0.0 0.14 11.7 0.0 4.0 6 0 0 6 6 6 0 PsbJ DUF1640 PF07798.6 EPE34111.1 - 1.8e-12 47.6 5.1 2.4e-12 47.2 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1866 PF08952.6 EPE34112.1 - 0.024 14.1 0.1 0.052 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) bZIP_1 PF00170.16 EPE34112.1 - 0.026 14.4 2.0 0.026 14.4 1.4 1.7 2 0 0 2 2 2 0 bZIP transcription factor Methyltransf_9 PF08003.6 EPE34112.1 - 0.19 10.3 0.9 0.28 9.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Vps51 PF08700.6 EPE34113.1 - 2.1e-11 43.4 0.0 1e-10 41.3 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 ELFV_dehydrog PF00208.16 EPE34114.1 - 6.8e-58 196.1 0.0 1.7e-57 194.7 0.0 1.7 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EPE34114.1 - 1.6e-21 75.6 0.0 1.3e-16 59.3 0.0 2.4 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase Aminotran_5 PF00266.14 EPE34115.1 - 8.7e-15 54.3 0.0 1.2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cohesin_load PF10345.4 EPE34116.1 - 5.9e-141 470.6 0.0 7.5e-141 470.3 0.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor Abhydrolase_1 PF00561.15 EPE34117.1 - 2.6e-08 33.7 0.0 4.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE34117.1 - 7e-08 32.6 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EPE34117.1 - 0.012 15.3 0.0 0.048 13.3 0.0 1.8 2 0 0 2 2 2 0 Cutinase IGPD PF00475.13 EPE34119.1 - 1.6e-58 196.6 0.3 2e-58 196.3 0.2 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Rep_fac_C PF08542.6 EPE34121.1 - 5.7e-21 74.2 0.0 1.2e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPE34121.1 - 7.2e-12 45.2 0.0 5.9e-10 39.0 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EPE34121.1 - 6.6e-11 42.5 0.0 1.5e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EPE34121.1 - 5.4e-07 29.5 0.0 1.8e-06 27.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPE34121.1 - 9.7e-06 24.7 0.0 3e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPE34121.1 - 1.5e-05 25.0 0.0 0.00033 20.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPE34121.1 - 4.3e-05 23.6 0.2 0.11 12.6 0.1 2.8 2 1 1 3 3 3 2 AAA domain Rad17 PF03215.10 EPE34121.1 - 6.4e-05 21.8 0.0 0.022 13.4 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 EPE34121.1 - 0.00013 21.5 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EPE34121.1 - 0.00014 21.4 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EPE34121.1 - 0.00017 21.1 0.1 0.037 13.4 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain DEAD PF00270.24 EPE34121.1 - 0.0015 18.0 0.2 0.11 12.0 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase DNA_pol3_delta PF06144.8 EPE34121.1 - 0.0021 17.6 0.1 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 EPE34121.1 - 0.0034 16.8 0.1 0.028 13.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EPE34121.1 - 0.0065 15.6 0.0 0.067 12.3 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EPE34121.1 - 0.0096 15.6 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain ArgK PF03308.11 EPE34121.1 - 0.0098 14.7 0.1 0.029 13.1 0.0 1.7 1 1 1 2 2 2 1 ArgK protein AAA_11 PF13086.1 EPE34121.1 - 0.012 15.1 0.1 0.021 14.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EPE34121.1 - 0.013 15.1 0.5 0.065 12.9 0.1 2.2 2 1 1 3 3 2 0 NTPase KTI12 PF08433.5 EPE34121.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 EPE34121.1 - 0.027 14.7 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EPE34121.1 - 0.031 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_31 PF13614.1 EPE34121.1 - 0.044 13.7 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPE34121.1 - 0.065 12.9 0.1 0.29 10.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EPE34121.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DNA_pol3_gamma3 PF12169.3 EPE34121.1 - 0.14 11.9 0.5 1.8 8.2 0.0 2.7 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III Cupin_1 PF00190.17 EPE34122.1 - 3.6e-12 45.9 0.2 5.8e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EPE34122.1 - 0.039 13.4 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Cupin domain Glyco_hydro_18 PF00704.23 EPE34124.1 - 7.6e-45 153.8 0.2 9e-45 153.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pet127 PF08634.5 EPE34125.1 - 4.2e-118 393.4 2.9 6.4e-118 392.8 2.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Peptidase_C48 PF02902.14 EPE34126.1 - 3.1e-38 131.5 0.0 6.9e-38 130.4 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3435 PF11917.3 EPE34129.1 - 0.0095 14.7 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF410 PF04190.8 EPE34130.1 - 4.4e-49 167.3 0.0 5.2e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) PV-1 PF06637.6 EPE34130.1 - 0.18 10.3 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) RAI1 PF08652.6 EPE34132.1 - 2.1e-27 94.7 0.0 4.1e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Malic_M PF03949.10 EPE34133.1 - 5.3e-90 301.4 0.0 6.9e-90 301.0 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EPE34133.1 - 2.2e-62 209.8 0.0 3.4e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain EF-hand_9 PF14658.1 EPE34133.1 - 0.091 12.6 0.2 19 5.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain OPT PF03169.10 EPE34134.1 - 7.6e-156 520.1 22.7 8.8e-156 519.9 15.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Gly-zipper_Omp PF13488.1 EPE34134.1 - 0.34 10.5 6.4 0.15 11.7 0.2 3.2 3 0 0 3 3 3 0 Glycine zipper SWIB PF02201.13 EPE34135.1 - 7.6e-12 44.7 0.0 1.6e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain CENP-B_dimeris PF09026.5 EPE34135.1 - 1.2 9.4 14.9 0.52 10.5 7.4 2.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 EPE34135.1 - 2 6.1 5.4 2.7 5.7 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 EPE34135.1 - 4.9 6.6 11.1 10 5.6 7.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Mo25 PF08569.6 EPE34136.1 - 5.9e-125 416.7 0.1 6.7e-125 416.5 0.0 1.0 1 0 0 1 1 1 1 Mo25-like PrmA PF06325.8 EPE34137.1 - 1.2e-11 44.2 0.0 2.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EPE34137.1 - 4e-11 42.7 0.0 7.2e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE34137.1 - 2.3e-10 41.0 0.0 5.1e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE34137.1 - 3.1e-09 37.2 0.0 9e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE34137.1 - 1.1e-08 35.0 0.0 2.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE34137.1 - 4e-07 29.5 0.1 7e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EPE34137.1 - 1.3e-06 28.6 0.0 3.6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE34137.1 - 1.4e-06 28.1 0.0 2.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPE34137.1 - 1.8e-05 24.0 0.0 3.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EPE34137.1 - 0.00046 20.5 0.1 0.0011 19.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PRMT5 PF05185.11 EPE34137.1 - 0.00072 18.5 0.0 0.00087 18.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase FtsJ PF01728.14 EPE34137.1 - 0.0012 18.9 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EPE34137.1 - 0.0013 17.8 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EPE34137.1 - 0.0035 16.8 0.0 0.007 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Met_10 PF02475.11 EPE34137.1 - 0.0043 16.6 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 EPE34137.1 - 0.0091 15.5 0.1 0.019 14.5 0.1 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.14 EPE34137.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 EPE34137.1 - 0.012 14.3 0.0 0.023 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) WD40_alt PF14077.1 EPE34137.1 - 0.064 12.8 2.2 0.09 12.4 0.8 1.8 1 1 1 2 2 2 0 Alternative WD40 repeat motif TehB PF03848.9 EPE34137.1 - 0.089 11.9 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 EPE34137.1 - 0.094 13.5 0.0 0.43 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Pyridox_ox_2 PF12900.2 EPE34138.1 - 2.1e-37 128.1 0.0 2.9e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AA_permease PF00324.16 EPE34140.1 - 2.6e-67 227.2 29.6 8.5e-67 225.5 20.5 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE34140.1 - 1.8e-25 89.3 25.1 3e-25 88.6 17.4 1.4 1 1 1 2 2 2 1 Amino acid permease DUF983 PF06170.7 EPE34140.1 - 0.05 13.7 4.3 0.11 12.6 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF983) EspB PF05802.6 EPE34140.1 - 0.13 11.2 1.1 2.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Enterobacterial EspB protein Glyco_hydro_35 PF01301.14 EPE34142.1 - 1.1e-73 248.4 3.4 1.1e-72 245.1 2.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EPE34142.1 - 3.4e-61 205.7 0.8 7.1e-61 204.7 0.6 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EPE34142.1 - 4.9e-47 158.7 9.5 3.9e-24 85.0 1.5 3.6 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EPE34142.1 - 5.2e-23 80.2 0.0 2e-22 78.3 0.0 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Polysacc_deac_1 PF01522.16 EPE34144.1 - 6.4e-29 100.1 0.0 1.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EPE34144.1 - 2.4e-20 72.2 89.6 1.1e-09 38.0 13.1 5.2 5 0 0 5 5 5 3 Chitin recognition protein CDC27 PF09507.5 EPE34144.1 - 0.04 13.1 2.2 0.052 12.7 1.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Csm1 PF12539.3 EPE34145.1 - 6.4e-24 84.2 0.1 1.6e-23 82.9 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Reo_sigmaC PF04582.7 EPE34145.1 - 0.0015 17.8 2.4 0.0028 16.9 1.7 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Spc42p PF11544.3 EPE34145.1 - 0.02 14.8 2.9 0.02 14.8 2.0 2.9 1 1 1 2 2 2 0 Spindle pole body component Spc42p DUF743 PF05332.6 EPE34145.1 - 0.021 14.7 0.1 0.021 14.7 0.0 3.6 3 2 0 3 3 3 0 Protein of unknown function (DUF743) COG2 PF06148.6 EPE34145.1 - 0.1 12.4 3.3 0.31 10.9 2.3 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2024 PF09630.5 EPE34145.1 - 0.12 12.1 0.0 0.43 10.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) HAUS-augmin3 PF14932.1 EPE34145.1 - 0.57 9.3 17.5 0.013 14.6 5.6 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Fungal_trans PF04082.13 EPE34147.1 - 5.2e-33 114.0 0.0 2.1e-32 112.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE34147.1 - 0.018 14.9 3.9 0.033 14.0 2.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PigN PF04987.9 EPE34148.1 - 4.5e-140 467.1 27.4 2.2e-88 296.8 8.1 2.1 2 0 0 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EPE34148.1 - 3.9e-10 39.6 0.4 1.2e-08 34.7 0.3 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPE34148.1 - 5.2e-09 35.7 0.1 7.7e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EPE34148.1 - 0.00097 18.5 0.1 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Isochorismatase PF00857.15 EPE34149.1 - 4.7e-30 104.7 0.0 5.7e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF3716 PF12511.3 EPE34150.1 - 1.5e-16 59.6 5.3 2.9e-16 58.7 3.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF4246 PF14033.1 EPE34151.1 - 1.2e-163 545.3 0.0 1.4e-163 545.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Arv1 PF04161.8 EPE34152.1 - 2.5e-36 125.5 4.1 1.2e-17 64.5 0.0 2.1 1 1 1 2 2 2 2 Arv1-like family ATP_synt_H PF05493.8 EPE34153.1 - 8.6e-26 89.8 3.4 9.3e-26 89.6 2.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Polysacc_synt_C PF14667.1 EPE34153.1 - 0.0032 17.2 2.0 0.0032 17.2 1.4 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain ABC2_membrane_4 PF12730.2 EPE34153.1 - 0.015 14.4 3.1 0.018 14.1 2.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein AmiS_UreI PF02293.10 EPE34153.1 - 0.028 14.0 0.2 0.033 13.8 0.1 1.0 1 0 0 1 1 1 0 AmiS/UreI family transporter Claudin_2 PF13903.1 EPE34153.1 - 0.053 13.2 3.0 0.062 12.9 2.0 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pox_A14 PF05767.7 EPE34153.1 - 0.056 13.4 1.5 0.065 13.2 1.1 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 5TM-5TMR_LYT PF07694.7 EPE34153.1 - 0.058 12.7 3.9 0.064 12.5 2.7 1.0 1 0 0 1 1 1 0 5TMR of 5TMR-LYT ABC2_membrane_2 PF12679.2 EPE34153.1 - 0.33 9.7 3.0 0.42 9.4 2.1 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4131 PF13567.1 EPE34153.1 - 0.6 9.5 3.4 0.69 9.3 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Anoctamin PF04547.7 EPE34153.1 - 1.2 7.6 3.9 1.5 7.3 2.7 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel FtsX PF02687.16 EPE34153.1 - 3.4 7.4 6.3 5.3 6.8 4.3 1.3 1 1 0 1 1 1 0 FtsX-like permease family NAD_binding_2 PF03446.10 EPE34154.1 - 8.8e-31 106.9 0.1 1.4e-30 106.3 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EPE34154.1 - 1.5e-12 47.7 0.0 4.9e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EPE34154.1 - 1.3e-08 35.0 0.0 2.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.1 EPE34154.1 - 2.3e-08 34.1 0.1 7.6e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EPE34154.1 - 0.0016 17.8 0.3 0.0077 15.6 0.2 2.0 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EPE34154.1 - 0.0025 17.8 0.1 0.0069 16.3 0.0 1.8 1 1 0 1 1 1 1 TrkA-N domain OCD_Mu_crystall PF02423.10 EPE34154.1 - 0.0046 15.7 0.0 0.0084 14.9 0.0 1.4 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Semialdhyde_dh PF01118.19 EPE34154.1 - 0.0092 16.2 0.0 0.025 14.8 0.0 1.7 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EPE34154.1 - 0.023 15.2 0.0 0.061 13.8 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 EPE34154.1 - 0.029 13.3 0.1 0.038 12.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 EPE34154.1 - 0.032 13.9 0.2 0.08 12.6 0.1 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FRQ PF09421.5 EPE34155.1 - 2.3e-146 489.1 40.3 5.9e-87 292.5 17.7 2.3 1 1 1 2 2 2 2 Frequency clock protein Leu_zip PF15294.1 EPE34155.1 - 0.004 16.3 0.1 0.0079 15.3 0.1 1.4 1 0 0 1 1 1 1 Leucine zipper bZIP_1 PF00170.16 EPE34155.1 - 0.29 11.1 3.5 2.3 8.2 0.1 2.6 2 0 0 2 2 2 0 bZIP transcription factor CoA_trans PF01144.18 EPE34157.1 - 9.6e-101 335.4 3.5 7.9e-61 204.9 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EPE34157.1 - 0.006 16.2 0.0 0.016 14.8 0.0 1.7 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_47 PF01532.15 EPE34159.1 - 4.2e-178 592.6 0.1 5.4e-178 592.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 UPF0515 PF15135.1 EPE34159.1 - 0.16 10.9 1.7 0.34 9.9 1.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Cpn60_TCP1 PF00118.19 EPE34160.1 - 8.6e-146 486.3 0.3 9.9e-146 486.1 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Prenylcys_lyase PF07156.9 EPE34161.1 - 1.7e-33 116.0 0.0 9.1e-33 113.6 0.0 1.9 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EPE34161.1 - 5.9e-13 48.6 0.1 1.6e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EPE34161.1 - 4.7e-06 25.9 0.0 0.00012 21.2 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EPE34161.1 - 8.5e-05 21.6 0.3 0.00079 18.4 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPE34161.1 - 0.0007 19.5 0.2 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE34161.1 - 0.00073 19.3 0.1 0.0094 15.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPE34161.1 - 0.0085 16.1 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE34161.1 - 0.034 13.2 0.5 0.14 11.2 0.1 1.9 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 EPE34161.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EPE34161.1 - 0.11 12.9 0.2 1.3 9.5 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CP2 PF04516.10 EPE34162.1 - 3.7e-88 294.5 1.2 4.1e-88 294.4 0.0 1.7 2 0 0 2 2 2 1 CP2 transcription factor Phage_G PF02306.10 EPE34162.1 - 0.015 14.9 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 Major spike protein (G protein) Tektin PF03148.9 EPE34162.1 - 0.037 12.5 0.0 0.066 11.7 0.0 1.3 1 0 0 1 1 1 0 Tektin family DUF2681 PF10883.3 EPE34162.1 - 1.1 9.4 4.2 1 9.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) HET PF06985.6 EPE34166.1 - 3.4e-29 101.7 0.2 6.4e-29 100.8 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Exostosin PF03016.10 EPE34166.1 - 0.041 12.9 0.0 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Exostosin family E1-E2_ATPase PF00122.15 EPE34166.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 E1-E2 ATPase Peptidase_S41 PF03572.13 EPE34167.1 - 6e-07 29.0 0.0 2e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 Fructosamin_kin PF03881.9 EPE34169.1 - 4.2e-33 114.5 0.0 5.6e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EPE34169.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 EPE34170.1 - 2.2e-06 26.5 0.4 3.9e-06 25.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain C1_1 PF00130.17 EPE34170.1 - 0.083 12.6 0.5 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EPE34170.1 - 0.21 11.3 1.0 0.34 10.6 0.7 1.3 1 0 0 1 1 1 0 PHD-finger DLH PF01738.13 EPE34171.1 - 4.6e-06 26.0 0.0 7.7e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family ADH_zinc_N_2 PF13602.1 EPE34172.1 - 8.2e-19 68.7 0.0 1.5e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EPE34172.1 - 4.1e-15 55.4 0.1 8.2e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EPE34172.1 - 0.00027 20.9 0.3 0.00047 20.2 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF4058 PF13267.1 EPE34173.1 - 0.18 10.8 5.4 0.29 10.2 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) DUF347 PF03988.7 EPE34174.1 - 0.02 14.7 0.3 0.03 14.2 0.2 1.2 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) SKG6 PF08693.5 EPE34174.1 - 0.097 12.0 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Zn_clus PF00172.13 EPE34175.1 - 8.6e-05 22.3 12.3 8.6e-05 22.3 8.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Isochorismatase PF00857.15 EPE34176.1 - 3.7e-37 127.9 0.0 4.5e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family COesterase PF00135.23 EPE34177.1 - 1.9e-76 257.9 0.0 2.9e-76 257.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE34177.1 - 4.2e-08 33.0 0.1 1.1e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE34177.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE34177.1 - 0.046 12.9 0.4 0.08 12.1 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE34177.1 - 0.061 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.13 EPE34179.1 - 8.2e-07 28.8 10.0 1.5e-06 28.0 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 EPE34180.1 - 7.8e-13 48.7 0.0 2.1e-12 47.2 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EPE34180.1 - 0.034 12.7 0.0 3.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EPE34180.1 - 0.059 12.4 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EPE34180.1 - 0.098 12.2 0.0 0.29 10.6 0.0 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase ECR1_N PF14382.1 EPE34181.1 - 8e-13 47.4 0.0 1.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EPE34181.1 - 0.0018 18.1 0.0 0.04 13.8 0.0 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EPE34181.1 - 0.0068 16.4 2.8 0.063 13.3 0.0 3.3 4 0 0 4 4 4 1 S1 RNA binding domain ADH_N PF08240.7 EPE34182.1 - 1.9e-23 82.2 1.3 3.8e-23 81.3 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE34182.1 - 1e-13 50.9 0.0 1.7e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPE34182.1 - 0.00019 20.6 0.1 0.00039 19.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EPE34182.1 - 0.00048 21.0 0.0 0.0017 19.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EPE34182.1 - 0.018 14.6 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EPE34182.1 - 0.038 13.8 0.5 0.08 12.7 0.1 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EPE34182.1 - 0.082 12.5 0.2 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4536 PF15055.1 EPE34183.1 - 0.00012 22.0 1.8 0.001 19.1 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4536) Adap_comp_sub PF00928.16 EPE34184.1 - 8.8e-62 208.5 0.0 1.1e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EPE34184.1 - 0.0006 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SNF2_N PF00176.18 EPE34187.1 - 1.9e-75 253.4 0.2 3.4e-75 252.6 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EPE34187.1 - 8.8e-44 148.0 1.1 2.4e-43 146.5 0.8 1.8 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 EPE34187.1 - 3.3e-35 120.9 1.2 3.3e-35 120.9 0.9 3.6 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EPE34187.1 - 1.3e-14 53.8 0.0 3.1e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE34187.1 - 7.3e-07 29.1 0.1 4.9e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EPE34187.1 - 6.9e-06 25.0 0.0 1.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EPE34187.1 - 1.3e-05 24.7 0.0 3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 EPE34187.1 - 0.007 16.3 0.0 1.5 8.9 0.0 3.8 4 0 0 4 4 4 1 Myb-like DNA-binding domain DEAD_2 PF06733.10 EPE34187.1 - 0.026 13.9 0.1 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 DUF4588 PF15251.1 EPE34188.1 - 3.2e-05 24.0 6.9 6e-05 23.1 4.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) HAD_2 PF13419.1 EPE34189.1 - 1e-09 38.8 0.0 1.2e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE34189.1 - 8.3e-06 25.4 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EPE34189.1 - 0.002 18.5 0.0 0.0026 18.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EPE34190.1 - 1.2e-58 198.3 0.0 1.6e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE34190.1 - 7.2e-40 136.6 0.0 9.6e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE34190.1 - 1.6e-06 27.2 0.0 4.6e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 EPE34190.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SH2_2 PF14633.1 EPE34191.1 - 2.1e-83 278.7 0.1 4.8e-83 277.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 EPE34191.1 - 9.7e-38 128.8 5.3 9.7e-38 128.8 3.7 3.0 2 0 0 2 2 2 1 Death-like domain of SPT6 HHH_7 PF14635.1 EPE34191.1 - 7.8e-32 109.4 0.0 1.6e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EPE34191.1 - 3.9e-30 104.3 0.0 1.1e-29 102.9 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EPE34191.1 - 4.5e-22 78.0 26.5 4.5e-22 78.0 18.4 6.1 7 0 0 7 7 7 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EPE34191.1 - 5e-18 65.2 0.9 5e-18 65.2 0.7 3.2 3 1 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_3 PF12836.2 EPE34191.1 - 0.027 14.4 0.0 0.21 11.5 0.0 2.5 3 0 0 3 3 3 0 Helix-hairpin-helix motif B12-binding PF02310.14 EPE34191.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Oxysterol_BP PF01237.13 EPE34192.1 - 1.1e-103 346.4 0.0 2.5e-103 345.2 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EPE34192.1 - 1.4e-37 127.6 2.1 2.5e-37 126.8 0.0 2.4 3 0 0 3 3 3 1 Pleckstrin homology domain GOLD_2 PF13897.1 EPE34192.1 - 0.00011 22.4 0.0 0.0003 21.0 0.0 1.7 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking PH PF00169.24 EPE34192.1 - 0.0023 18.1 0.0 0.0048 17.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EPE34192.1 - 0.0052 17.0 1.3 0.2 11.8 0.9 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Amidohydro_4 PF13147.1 EPE34193.1 - 5.3e-08 33.2 0.0 1.3e-07 31.9 0.0 1.5 1 1 1 2 2 2 1 Amidohydrolase Amidohydro_2 PF04909.9 EPE34193.1 - 6e-06 26.0 0.0 1.4e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase CheF-arch PF04283.7 EPE34194.1 - 0.039 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Chemotaxis signal transduction system protein F from archaea SMN PF06003.7 EPE34195.1 - 4.1 6.4 10.4 10 5.1 7.2 1.6 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zf-PHD-like PF15446.1 EPE34196.1 - 1.3e-66 223.1 11.5 2.9e-66 222.0 8.0 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EPE34196.1 - 1.6e-53 181.4 0.2 8e-53 179.1 0.0 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE34196.1 - 6.5e-16 57.9 0.0 4.1e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EPE34196.1 - 3.5e-15 55.5 0.1 8.8e-15 54.2 0.1 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 EPE34196.1 - 3.4e-06 26.6 3.7 0.022 14.4 1.0 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EPE34196.1 - 0.0015 18.1 4.7 0.0015 18.1 3.3 3.3 3 1 0 3 3 3 1 PHD-finger DEAD PF00270.24 EPE34196.1 - 0.0022 17.4 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD_2 PF13831.1 EPE34196.1 - 0.0028 16.9 9.0 0.0034 16.6 4.0 2.9 2 1 0 2 2 2 1 PHD-finger C1_1 PF00130.17 EPE34196.1 - 0.57 9.9 7.6 2.1 8.1 0.9 2.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ferric_reduct PF01794.14 EPE34197.1 - 2.1e-17 63.3 6.5 2.1e-17 63.3 4.5 3.0 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EPE34197.1 - 7.5e-13 48.6 0.0 1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EPE34197.1 - 1.2e-11 44.3 0.0 1.3e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 EPE34197.1 - 0.024 15.2 0.0 0.067 13.7 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain E1-E2_ATPase PF00122.15 EPE34198.1 - 1.5e-50 171.3 0.5 2.8e-50 170.5 0.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPE34198.1 - 1.2e-33 116.2 4.9 1.2e-33 116.2 3.4 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPE34198.1 - 2e-29 103.5 0.0 2.2e-28 100.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPE34198.1 - 5.4e-18 65.8 0.0 3e-17 63.4 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPE34198.1 - 2.2e-16 59.5 0.0 4.1e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EPE34198.1 - 8.7e-14 50.7 0.0 2.2e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPE34198.1 - 0.00039 20.0 0.3 0.0011 18.5 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Phage_connector PF05352.7 EPE34198.1 - 0.077 12.1 0.3 0.16 11.1 0.1 1.5 2 0 0 2 2 2 0 Phage Connector (GP10) Fer2 PF00111.22 EPE34200.1 - 2.9e-10 39.7 2.9 4.1e-10 39.2 2.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.7 EPE34201.1 - 8.4e-31 106.7 8.7 8.4e-31 106.7 6.1 2.0 3 0 0 3 3 3 1 Rrp15p SRP54 PF00448.17 EPE34202.1 - 6.6e-77 257.3 3.3 8e-77 257.1 1.3 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EPE34202.1 - 4.2e-25 88.0 5.3 4.2e-25 88.0 3.7 4.1 3 2 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.14 EPE34202.1 - 6.4e-16 58.2 0.9 1.5e-15 57.0 0.6 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EPE34202.1 - 2.5e-09 36.8 0.2 7.8e-09 35.2 0.1 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EPE34202.1 - 1.3e-07 31.5 0.1 2.8e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE34202.1 - 1.5e-05 25.8 0.0 3.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EPE34202.1 - 1.6e-05 24.6 0.0 4.7e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EPE34202.1 - 1.7e-05 23.9 0.0 4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.18 EPE34202.1 - 6.2e-05 22.4 0.2 0.00021 20.7 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EPE34202.1 - 0.00034 20.5 0.0 0.57 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EPE34202.1 - 0.00058 18.7 1.4 0.0046 15.7 0.9 2.2 1 1 0 1 1 1 1 ArgK protein APS_kinase PF01583.15 EPE34202.1 - 0.00066 19.3 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 EPE34202.1 - 0.0018 18.2 0.0 0.0046 16.9 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPE34202.1 - 0.0023 18.0 0.0 0.0079 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EPE34202.1 - 0.0029 17.1 0.4 0.017 14.6 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EPE34202.1 - 0.0053 17.0 0.0 0.014 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EPE34202.1 - 0.0066 15.8 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 Thymidylate kinase Torsin PF06309.6 EPE34202.1 - 0.0067 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_28 PF13521.1 EPE34202.1 - 0.014 15.4 0.1 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 EPE34202.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SRPRB PF09439.5 EPE34202.1 - 0.021 14.0 1.9 5.8 6.1 1.4 3.0 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EPE34202.1 - 0.026 13.9 0.1 0.045 13.1 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain TrwB_AAD_bind PF10412.4 EPE34202.1 - 0.031 12.8 0.0 0.064 11.8 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Spectrin PF00435.16 EPE34202.1 - 0.057 13.7 0.2 0.17 12.2 0.0 1.8 2 0 0 2 2 1 0 Spectrin repeat AAA PF00004.24 EPE34202.1 - 0.061 13.5 0.3 0.18 12.0 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) VirE PF05272.6 EPE34202.1 - 0.091 12.2 0.0 0.28 10.6 0.0 1.8 1 1 1 2 2 2 0 Virulence-associated protein E AAA PF00004.24 EPE34203.1 - 5.6e-40 136.5 1.1 4.5e-14 52.7 0.0 5.7 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 EPE34203.1 - 3.7e-39 134.1 0.1 2e-38 131.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EPE34203.1 - 2.1e-27 96.1 18.9 3.2e-23 82.5 0.0 6.4 5 1 0 5 5 5 2 AAA domain AAA_19 PF13245.1 EPE34203.1 - 1.4e-16 59.9 4.3 5.3e-05 22.8 0.0 5.0 4 0 0 4 4 4 4 Part of AAA domain AAA_22 PF13401.1 EPE34203.1 - 4.1e-13 49.6 9.2 0.0061 16.7 0.2 7.3 5 3 0 5 5 4 2 AAA domain AAA_5 PF07728.9 EPE34203.1 - 3e-11 43.2 4.1 0.049 13.3 0.0 5.6 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPE34203.1 - 1.4e-10 41.4 6.4 0.086 12.8 0.0 5.8 5 0 0 5 5 5 3 AAA ATPase domain AAA_30 PF13604.1 EPE34203.1 - 2.4e-09 37.0 6.7 0.3 10.6 0.0 6.3 5 2 0 5 5 5 3 AAA domain Mg_chelatase PF01078.16 EPE34203.1 - 1.3e-07 31.0 0.3 0.1 11.7 0.0 4.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EPE34203.1 - 2e-07 30.9 5.8 0.42 10.4 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 EPE34203.1 - 2.2e-07 31.7 26.7 0.13 13.0 0.0 7.1 7 0 0 7 7 5 4 AAA domain KaiC PF06745.8 EPE34203.1 - 2.9e-06 26.5 1.3 0.0071 15.4 0.0 4.4 4 0 0 4 4 4 1 KaiC IstB_IS21 PF01695.12 EPE34203.1 - 9.1e-06 25.2 0.1 5.5 6.3 0.0 4.6 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EPE34203.1 - 9.2e-06 25.7 0.7 5.7 7.1 0.0 4.7 4 0 0 4 4 4 1 RNA helicase AAA_18 PF13238.1 EPE34203.1 - 9.5e-05 22.7 16.7 1.6 9.0 0.0 5.9 5 0 0 5 5 4 3 AAA domain Torsin PF06309.6 EPE34203.1 - 0.0034 17.2 0.1 56 3.6 0.0 4.4 4 0 0 4 4 4 0 Torsin AAA_24 PF13479.1 EPE34203.1 - 0.004 16.7 12.6 0.44 10.0 0.0 5.0 5 0 0 5 5 5 1 AAA domain Guanylate_cyc_2 PF09778.4 EPE34203.1 - 0.0052 16.0 0.0 6 5.9 0.0 3.2 3 0 0 3 3 3 1 Guanylylate cyclase AAA_25 PF13481.1 EPE34203.1 - 0.021 14.2 7.7 0.7 9.2 0.0 4.8 4 1 0 4 4 4 0 AAA domain DUF2075 PF09848.4 EPE34203.1 - 0.022 13.7 0.0 0.022 13.7 0.0 5.7 6 1 0 6 6 6 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EPE34203.1 - 0.32 10.9 14.5 4.1 7.3 0.0 5.4 5 0 0 5 5 5 0 AAA domain AAA_10 PF12846.2 EPE34203.1 - 0.33 10.3 14.9 13 5.0 0.1 5.7 4 2 0 4 4 4 0 AAA-like domain SRP54 PF00448.17 EPE34203.1 - 2.6 7.4 8.9 0.39 10.1 0.1 3.7 3 1 0 3 3 3 0 SRP54-type protein, GTPase domain HET PF06985.6 EPE34206.1 - 2.9e-14 53.4 3.8 9.7e-12 45.2 0.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ADH_zinc_N PF00107.21 EPE34207.1 - 2.5e-21 75.5 0.0 7.2e-21 74.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE34207.1 - 3.5e-14 53.7 0.0 6.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE34207.1 - 5.5e-10 38.9 0.0 2.4e-09 36.9 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain WD40 PF00400.27 EPE34208.1 - 3e-30 102.9 0.0 1.5e-09 37.3 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EPE34208.1 - 9.5e-05 22.1 0.6 0.01 15.5 0.1 2.9 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EPE34208.1 - 0.00017 20.5 0.6 0.097 11.4 0.1 2.2 1 1 1 2 2 2 2 Coatomer WD associated region PQQ_2 PF13360.1 EPE34208.1 - 0.0021 17.5 0.7 0.0086 15.5 0.5 2.0 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 EPE34208.1 - 0.0039 15.9 0.0 0.66 8.6 0.0 2.4 1 1 1 2 2 2 2 Nup133 N terminal like Gmad1 PF10647.4 EPE34208.1 - 0.061 12.6 0.3 0.25 10.6 0.1 1.8 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EPE34208.1 - 0.07 11.2 0.0 0.11 10.6 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 FTHFS PF01268.14 EPE34209.1 - 5.9e-256 849.8 0.7 8.1e-256 849.3 0.5 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EPE34209.1 - 2.2e-65 218.6 1.2 2.2e-65 218.6 0.8 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EPE34209.1 - 2.9e-37 127.2 0.5 6.8e-37 126.0 0.4 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 EPE34209.1 - 0.016 14.6 0.4 0.053 12.9 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Kinetocho_Slk19 PF12709.2 EPE34210.1 - 1e-20 73.5 1.3 1e-20 73.5 0.9 4.0 3 1 1 4 4 4 2 Central kinetochore-associated CENP-Q PF13094.1 EPE34210.1 - 0.0014 18.6 6.0 0.0014 18.6 4.2 3.1 2 1 1 3 3 3 2 CENP-Q, a CENPA-CAD centromere complex subunit NPV_P10 PF05531.7 EPE34210.1 - 0.13 12.4 0.4 12 6.2 0.1 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 EPE34210.1 - 0.23 10.3 18.7 0.02 13.8 2.3 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 EPE34210.1 - 0.23 11.5 4.4 2.3 8.3 0.5 3.3 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EPE34210.1 - 2.6 7.5 26.9 0.45 10.0 7.0 2.9 3 1 0 3 3 3 0 IncA protein Acyltransferase PF01553.16 EPE34211.1 - 7.1e-05 22.2 0.0 0.00026 20.4 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase Tyrosinase PF00264.15 EPE34212.1 - 8.1e-48 163.5 0.4 1.1e-47 163.0 0.1 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase HET PF06985.6 EPE34213.1 - 8.9e-20 71.2 11.1 1.1e-18 67.7 1.7 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Filament PF00038.16 EPE34215.1 - 0.0013 18.2 5.4 0.0013 18.2 3.8 3.0 2 1 0 2 2 2 1 Intermediate filament protein Baculo_PEP_C PF04513.7 EPE34215.1 - 0.02 14.6 0.3 0.85 9.4 0.0 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 EPE34215.1 - 2.7 7.5 18.9 0.063 12.8 6.9 2.6 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ndc1_Nup PF09531.5 EPE34215.1 - 5.3 5.3 5.0 11 4.3 3.4 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4448 PF14610.1 EPE34217.1 - 0.012 15.0 0.6 0.015 14.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4202 PF13875.1 EPE34218.1 - 0.21 11.1 4.1 2.4 7.7 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4202) G-alpha PF00503.15 EPE34221.1 - 1.7e-84 283.8 0.0 2.9e-84 283.0 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EPE34221.1 - 5.1e-07 29.0 0.1 6.7e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EPE34221.1 - 0.0006 19.7 1.1 0.028 14.3 0.1 3.3 2 2 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EPE34221.1 - 0.0091 16.4 0.0 13 6.2 0.0 3.5 3 0 0 3 3 3 1 Miro-like protein MobB PF03205.9 EPE34221.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EPE34221.1 - 0.084 12.3 0.1 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EPE34221.1 - 0.095 11.8 7.3 0.21 10.6 0.0 3.6 4 0 0 4 4 4 0 Gtr1/RagA G protein conserved region Gln-synt_C PF00120.19 EPE34222.1 - 0.001 18.3 0.0 0.0032 16.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain SpoU_methylase PF00588.14 EPE34223.1 - 4.7e-28 97.8 0.0 7.9e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EPE34223.1 - 7e-05 22.9 0.0 0.00017 21.6 0.0 1.7 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding RXT2_N PF08595.6 EPE34230.1 - 1 9.1 4.1 0.44 10.3 0.6 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal DDE_3 PF13358.1 EPE34232.1 - 6.6e-29 100.5 0.0 2e-28 98.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.14 EPE34232.1 - 1e-08 34.5 0.0 1.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EPE34232.1 - 5e-06 26.6 0.0 8.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_33 PF13592.1 EPE34232.1 - 0.067 12.7 0.7 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn helix TPR_12 PF13424.1 EPE34234.1 - 5.5e-28 96.7 1.3 3.3e-15 55.7 0.2 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat Patatin PF01734.17 EPE34234.1 - 8.5e-25 87.8 0.0 2e-24 86.6 0.0 1.7 2 0 0 2 2 1 1 Patatin-like phospholipase TPR_10 PF13374.1 EPE34234.1 - 5.8e-23 80.0 2.0 1.9e-13 49.8 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.17 EPE34234.1 - 2.4e-16 59.4 0.0 3.8e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 EPE34234.1 - 4.1e-08 32.7 0.5 1.9e-07 30.6 0.3 2.3 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EPE34234.1 - 3.5e-06 26.4 3.1 0.00016 21.0 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EPE34234.1 - 1.4e-05 24.9 0.2 0.11 12.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPE34234.1 - 7.5e-05 22.2 3.0 0.002 17.7 0.1 3.4 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPE34234.1 - 0.00067 19.3 0.3 0.015 15.1 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat AAA_22 PF13401.1 EPE34234.1 - 0.0075 16.4 0.0 0.025 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.1 EPE34234.1 - 0.012 16.3 0.2 0.29 11.8 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPE34234.1 - 0.013 15.8 0.0 0.7 10.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPE34234.1 - 0.021 14.6 0.1 0.71 9.7 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPE34234.1 - 0.035 14.7 1.3 1.3 9.8 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_16 PF13191.1 EPE34234.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EPE34234.1 - 0.12 12.2 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NmrA PF05368.8 EPE34236.1 - 1.2e-28 99.9 0.5 1.7e-28 99.4 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE34236.1 - 2.6e-16 60.1 0.2 3.3e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EPE34236.1 - 1.1e-05 24.6 0.2 1.6e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EPE34236.1 - 8.3e-05 21.4 0.0 0.00017 20.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE34236.1 - 0.00027 20.4 0.0 0.00079 18.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EPE34236.1 - 0.0078 16.1 0.8 0.021 14.7 0.1 2.1 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EPE34236.1 - 0.021 15.0 0.1 0.056 13.7 0.1 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EPE34236.1 - 0.23 10.5 1.9 1.5 7.8 0.8 2.4 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fungal_trans PF04082.13 EPE34237.1 - 2.2e-10 39.8 0.5 1.2e-09 37.4 0.4 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE34237.1 - 2.9e-10 39.8 12.3 2.9e-10 39.8 8.6 2.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EPE34237.1 - 6.9e-08 32.3 15.3 0.00065 19.8 1.6 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE34237.1 - 2.3e-06 27.5 21.0 0.00014 21.9 0.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EPE34237.1 - 0.0062 16.7 4.4 0.39 11.0 0.5 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EPE34237.1 - 0.034 14.4 1.1 0.034 14.4 0.8 3.9 3 1 0 3 3 3 0 Zinc-finger double domain Nop10p PF04135.7 EPE34239.1 - 1.9e-19 69.1 0.3 3.3e-19 68.3 0.2 1.4 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ank_2 PF12796.2 EPE34239.1 - 2e-09 37.6 0.1 0.00057 20.1 0.3 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE34239.1 - 4e-05 23.2 0.4 0.27 11.1 0.0 4.9 5 1 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 EPE34239.1 - 7.8e-05 23.0 2.7 1.9 9.1 0.0 4.9 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE34239.1 - 0.00055 19.9 1.6 9 6.8 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 EPE34239.1 - 0.019 15.1 1.7 13 6.1 0.0 4.3 4 1 0 4 4 4 0 Ankyrin repeats (many copies) NOB1_Zn_bind PF08772.6 EPE34240.1 - 1.8e-32 110.9 2.9 3.3e-32 110.1 2.0 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EPE34240.1 - 0.034 14.0 10.6 0.15 12.0 7.4 2.1 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 EPE34240.1 - 0.16 11.4 1.8 0.64 9.5 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain EIIBC-GUT_N PF03612.9 EPE34240.1 - 0.35 10.4 2.3 0.62 9.6 0.0 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Ank_2 PF12796.2 EPE34242.1 - 1.5e-08 34.8 0.0 1.3e-06 28.6 0.0 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE34242.1 - 3e-06 26.7 0.0 0.18 11.7 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EPE34242.1 - 4e-05 23.7 0.2 0.69 10.2 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE34242.1 - 0.0011 19.4 0.1 2.2 8.8 0.1 3.2 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE34242.1 - 0.0048 17.0 0.1 4.6 7.7 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeat DUF2624 PF11116.3 EPE34242.1 - 0.075 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) DUF3609 PF12259.3 EPE34243.1 - 0.00049 18.8 0.0 0.00062 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) DUF4554 PF15091.1 EPE34243.1 - 1 7.9 5.1 0.56 8.8 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4554) Osteoregulin PF07175.6 EPE34244.1 - 0.025 14.3 0.5 1.6 8.5 0.0 2.0 1 1 1 2 2 2 0 Osteoregulin Fungal_trans PF04082.13 EPE34245.1 - 3.4e-10 39.2 6.2 5.2e-10 38.6 4.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.15 EPE34246.1 - 2.7e-64 217.4 0.3 4.9e-64 216.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EPE34246.1 - 2.6e-14 53.3 0.0 6.1e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Bac_rhamnosid PF05592.6 EPE34247.1 - 4.8e-21 74.5 0.1 8.1e-18 63.9 0.0 2.3 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 EPE34247.1 - 0.012 14.2 0.1 0.017 13.7 0.1 1.1 1 0 0 1 1 1 0 Trehalase DM13 PF10517.4 EPE34248.1 - 3.5e-10 40.2 0.0 5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Electron transfer DM13 Gly-zipper_OmpA PF13436.1 EPE34248.1 - 0.18 11.4 14.2 0.047 13.3 6.8 1.9 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain NAD_binding_6 PF08030.7 EPE34249.1 - 1.4e-20 73.7 0.2 3.3e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPE34249.1 - 4e-17 62.4 12.6 4e-17 62.4 8.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EPE34249.1 - 1.3e-14 53.9 0.0 2.7e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EPE34249.1 - 0.0032 18.0 0.0 0.083 13.4 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain p450 PF00067.17 EPE34250.1 - 6.7e-63 212.8 0.0 8.3e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GRA6 PF05084.8 EPE34252.1 - 0.032 13.7 0.5 0.053 13.0 0.2 1.5 1 1 0 1 1 1 0 Granule antigen protein (GRA6) SKG6 PF08693.5 EPE34252.1 - 0.046 13.0 0.2 0.13 11.6 0.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Vpu PF00558.14 EPE34252.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Vpu protein SSP160 PF06933.6 EPE34252.1 - 4.2 5.2 23.0 5.3 4.9 15.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CBAH PF02275.13 EPE34253.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.4 2 0 0 2 2 2 0 Linear amide C-N hydrolases, choloylglycine hydrolase family Class_IIIsignal PF04021.7 EPE34254.1 - 0.015 14.9 0.8 0.015 14.9 0.6 2.5 2 0 0 2 2 2 0 Class III signal peptide Tmemb_55A PF09788.4 EPE34255.1 - 0.056 12.5 0.2 0.098 11.7 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 55A DUF4231 PF14015.1 EPE34255.1 - 0.12 12.3 0.6 0.16 11.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF4480 PF13715.1 EPE34255.1 - 0.23 11.5 2.1 0.41 10.7 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) Adap_comp_sub PF00928.16 EPE34256.1 - 1.9e-91 305.8 0.0 2.5e-91 305.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EPE34256.1 - 1.9e-09 37.3 0.2 3.2e-09 36.6 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EPE34256.1 - 0.064 12.4 0.0 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Opi1 PF08618.5 EPE34257.1 - 6.5e-83 279.0 0.0 3.3e-67 227.2 0.0 3.1 1 1 1 2 2 2 2 Transcription factor Opi1 PAP2 PF01569.16 EPE34258.1 - 1.5e-19 69.9 0.0 3.4e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 PAP2 superfamily DnaJ PF00226.26 EPE34259.1 - 4e-11 42.4 0.5 9.3e-11 41.3 0.4 1.7 1 1 0 1 1 1 1 DnaJ domain DUF3795 PF12675.2 EPE34259.1 - 0.28 11.3 3.4 0.54 10.4 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) zf-HIT PF04438.11 EPE34259.1 - 1.7 8.3 6.9 0.42 10.3 2.2 1.9 2 0 0 2 2 2 0 HIT zinc finger Ribonucleas_3_3 PF14622.1 EPE34260.1 - 1.1e-06 28.6 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EPE34260.1 - 0.0066 16.8 0.8 0.046 14.1 0.0 2.6 3 1 0 3 3 3 1 Ribonuclease III domain DUF3638 PF12340.3 EPE34261.1 - 1.6e-94 315.2 0.5 2.8e-71 239.1 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EPE34261.1 - 2.8e-15 55.1 0.1 6.3e-15 54.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) OTT_1508_deam PF14441.1 EPE34262.1 - 2.4e-08 33.8 0.0 4.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase STAG PF08514.6 EPE34262.1 - 0.029 14.0 0.1 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 STAG domain Dynamin_N PF00350.18 EPE34263.1 - 2.2e-28 99.1 0.0 4e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EPE34263.1 - 2.8e-24 85.4 0.0 4e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EPE34263.1 - 0.00027 20.8 0.0 0.0015 18.4 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EPE34263.1 - 0.025 15.0 0.0 0.058 13.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_21 PF13304.1 EPE34263.1 - 0.048 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPRTase PF14681.1 EPE34264.1 - 1.1e-39 135.8 0.2 1.9e-39 135.0 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.2 EPE34264.1 - 8.2e-06 26.1 0.2 2.4e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 EPE34264.1 - 1.9e-05 25.4 0.0 4.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EPE34264.1 - 6.6e-05 22.0 0.0 9.9e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Pribosyltran PF00156.22 EPE34264.1 - 0.0001 22.0 0.3 0.017 14.8 0.1 2.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain AAA_33 PF13671.1 EPE34264.1 - 0.00013 21.8 0.1 0.0034 17.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPE34264.1 - 0.00029 20.0 0.0 0.002 17.2 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin PRTase_2 PF15609.1 EPE34264.1 - 0.00083 18.6 0.2 0.002 17.4 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase AAA_16 PF13191.1 EPE34264.1 - 0.0017 18.3 0.0 0.0071 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EPE34264.1 - 0.0019 18.5 0.0 0.0051 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Hydrolase PF00702.21 EPE34264.1 - 0.0039 17.6 0.0 0.0066 16.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Torsin PF06309.6 EPE34264.1 - 0.016 15.0 0.0 0.083 12.7 0.0 2.1 2 0 0 2 2 2 0 Torsin AAA PF00004.24 EPE34264.1 - 0.021 15.0 0.0 0.049 13.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE34264.1 - 0.028 14.5 0.1 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EPE34264.1 - 0.051 13.0 0.6 0.33 10.3 0.0 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EPE34264.1 - 0.16 11.8 0.0 0.62 9.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Hydrolase_3 PF08282.7 EPE34264.1 - 0.18 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HET PF06985.6 EPE34265.1 - 1.8e-06 28.1 0.0 3.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ifi-6-16 PF06140.8 EPE34266.1 - 1.3 8.8 13.1 3.6 7.4 9.1 1.7 1 1 0 1 1 1 0 Interferon-induced 6-16 family MutS_III PF05192.13 EPE34268.1 - 0.017 14.9 1.1 0.12 12.1 0.0 2.1 1 1 0 2 2 2 0 MutS domain III Reo_sigmaC PF04582.7 EPE34268.1 - 0.034 13.3 0.5 0.047 12.8 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CDC37_N PF03234.9 EPE34268.1 - 0.035 14.4 0.4 0.056 13.7 0.1 1.4 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF2390 PF09523.5 EPE34268.1 - 0.058 13.5 0.3 0.058 13.5 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2390) DUF3684 PF12449.3 EPE34269.1 - 0.012 13.2 0.0 0.015 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) Melibiase PF02065.13 EPE34270.1 - 1.6e-23 83.0 2.6 5.4e-19 68.1 0.0 3.3 1 1 1 2 2 2 2 Melibiase Raffinose_syn PF05691.7 EPE34270.1 - 0.0097 13.4 0.3 0.014 12.9 0.2 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_26 PF02156.10 EPE34271.1 - 2.9e-64 217.4 6.5 2.9e-64 217.4 4.5 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 26 CBM_1 PF00734.13 EPE34271.1 - 1.1e-09 37.7 11.2 2.7e-09 36.5 7.8 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.1 EPE34272.1 - 5e-16 59.3 0.1 6.7e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE34272.1 - 6.2e-14 52.3 0.0 7.9e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EPE34272.1 - 1.8e-05 24.5 0.0 2.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_61 PF03443.9 EPE34273.1 - 2.9e-38 131.8 3.6 7.1e-19 68.4 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 DUF1680 PF07944.7 EPE34274.1 - 3.7e-20 71.7 0.7 9.2e-17 60.4 0.0 2.4 2 1 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Alginate_lyase PF05426.7 EPE34275.1 - 5.3e-08 32.5 7.4 2e-07 30.6 5.1 1.7 1 1 0 1 1 1 1 Alginate lyase Aldo_ket_red PF00248.16 EPE34276.1 - 4.9e-51 173.2 0.1 6.1e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EPE34276.1 - 0.057 13.3 0.1 0.38 10.7 0.0 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family SLIDE PF09111.5 EPE34276.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 SLIDE MFS_1 PF07690.11 EPE34277.1 - 3.6e-30 104.8 34.1 3.9e-30 104.7 23.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily 2TM PF13239.1 EPE34277.1 - 0.49 10.4 0.0 0.49 10.4 0.0 4.6 5 0 0 5 5 5 0 2TM domain Fungal_trans PF04082.13 EPE34278.1 - 6.8e-20 71.0 0.1 1.5e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE34278.1 - 4.7e-07 29.6 14.4 8.8e-07 28.7 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.8 EPE34279.1 - 4.7e-18 65.3 0.4 6.4e-18 64.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Zn_clus PF00172.13 EPE34280.1 - 4.6e-07 29.6 8.7 1.1e-06 28.3 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 EPE34281.1 - 3.2e-11 42.9 0.0 4.9e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE34281.1 - 7.5e-08 32.5 0.0 1.3e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EPE34281.1 - 0.00024 21.3 0.0 0.00049 20.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EPE34281.1 - 0.00036 20.4 0.0 0.00073 19.4 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EPE34281.1 - 0.00082 18.8 0.0 0.0016 17.9 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPE34281.1 - 0.015 14.1 0.0 0.043 12.6 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 EPE34281.1 - 0.025 13.3 0.0 0.12 11.0 0.0 2.0 2 1 1 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPE34281.1 - 0.026 13.4 0.1 6 5.7 0.0 2.4 3 0 0 3 3 3 0 Male sterility protein TrkA_N PF02254.13 EPE34281.1 - 0.044 13.7 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.5 EPE34281.1 - 0.071 12.7 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 KR domain Pkinase PF00069.20 EPE34282.1 - 2.2e-17 63.0 0.0 3.3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EPE34282.1 - 0.00098 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EPE34282.1 - 0.006 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPE34282.1 - 0.027 13.5 0.0 0.089 11.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3317 PF11779.3 EPE34284.1 - 6.8 6.2 9.8 0.34 10.3 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) TRI12 PF06609.8 EPE34286.1 - 7.8e-27 93.7 28.8 1e-26 93.3 20.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EPE34286.1 - 5.7e-23 81.1 51.4 7.3e-22 77.5 30.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3667 PF12412.3 EPE34286.1 - 0.69 9.2 5.4 12 5.2 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3667) FAD_binding_3 PF01494.14 EPE34287.1 - 1.4e-17 63.8 0.0 6.1e-17 61.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE34287.1 - 2.5e-07 29.9 0.1 5.3e-06 25.5 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE34287.1 - 7.7e-07 29.0 0.2 1.7e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPE34287.1 - 9.4e-06 25.8 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE34287.1 - 7.1e-05 21.8 0.2 0.00011 21.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EPE34287.1 - 0.00013 21.9 0.1 0.00037 20.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPE34287.1 - 0.00024 20.3 0.2 0.00037 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPE34287.1 - 0.0003 21.1 0.1 0.0013 19.0 0.1 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE34287.1 - 0.001 17.6 0.7 0.0027 16.2 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EPE34287.1 - 0.0013 17.9 0.1 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 EPE34287.1 - 0.0015 18.2 0.3 0.033 13.9 0.0 2.7 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.19 EPE34287.1 - 0.0044 16.1 0.0 0.0098 15.0 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EPE34287.1 - 0.0075 14.9 0.0 1.5 7.3 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.17 EPE34287.1 - 0.01 14.7 0.1 0.015 14.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EPE34287.1 - 0.017 14.7 0.1 0.085 12.4 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EPE34287.1 - 0.041 13.3 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EPE34287.1 - 0.16 11.6 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Collagen PF01391.13 EPE34288.1 - 2.7e-37 126.0 153.5 5.4e-09 35.4 16.8 5.4 2 1 3 5 5 5 5 Collagen triple helix repeat (20 copies) WSC PF01822.14 EPE34288.1 - 0.00045 20.0 0.3 0.00081 19.2 0.2 1.4 1 0 0 1 1 1 1 WSC domain CPSF100_C PF13299.1 EPE34289.1 - 1.4e-41 142.3 0.4 3.9e-41 140.9 0.0 1.9 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EPE34289.1 - 1.3e-29 102.7 0.0 1.4e-28 99.3 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain APC_CDC26 PF10471.4 EPE34289.1 - 0.038 14.7 5.5 0.26 12.0 1.7 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 RMMBL PF07521.7 EPE34289.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase Sec23_trunk PF04811.10 EPE34290.1 - 2.4e-53 180.9 0.0 5.8e-53 179.7 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPE34290.1 - 2.6e-23 81.3 0.0 4.5e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPE34290.1 - 2e-18 66.7 0.0 3.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPE34290.1 - 7.9e-16 57.3 9.1 1.7e-15 56.2 6.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPE34290.1 - 1.6e-08 34.1 0.0 3.4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat SUR7 PF06687.7 EPE34291.1 - 2e-07 30.8 4.0 2.8e-07 30.3 2.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2976 PF11190.3 EPE34291.1 - 0.14 11.7 1.3 4.6 6.8 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) MFS_1 PF07690.11 EPE34292.1 - 1.6e-22 79.7 40.3 2e-22 79.3 27.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Beta-lactamase2 PF13354.1 EPE34293.1 - 0.15 11.4 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase enzyme family Zn_clus PF00172.13 EPE34294.1 - 1.8e-07 30.9 10.9 3e-07 30.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE34294.1 - 1.5e-05 24.0 0.0 2.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3802 PF12290.3 EPE34294.1 - 0.022 15.0 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) MFS_1 PF07690.11 EPE34295.1 - 2.7e-32 111.8 25.2 3.9e-32 111.3 17.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EPE34295.1 - 5.5e-05 21.7 13.0 5.5e-05 21.7 9.0 3.1 1 1 1 2 2 2 1 MFS/sugar transport protein DUF3948 PF13134.1 EPE34295.1 - 0.037 13.5 0.2 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) Cu_amine_oxid PF01179.15 EPE34296.1 - 3.7e-168 559.5 0.1 5.4e-168 558.9 0.1 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EPE34296.1 - 7.3e-14 51.6 0.1 1.6e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EPE34296.1 - 0.00079 19.4 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain UPF0546 PF10639.4 EPE34296.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 DUF1857 PF08982.6 EPE34297.1 - 1.2e-34 119.0 0.0 1.6e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Zn_clus PF00172.13 EPE34298.1 - 1.5e-07 31.2 13.5 1.5e-07 31.2 9.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE34298.1 - 0.031 13.1 0.3 0.062 12.1 0.2 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF4535 PF15054.1 EPE34299.1 - 0.33 10.3 2.4 0.75 9.2 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) SID-1_RNA_chan PF13965.1 EPE34299.1 - 1.8 6.6 5.9 2.3 6.2 4.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MFS_1 PF07690.11 EPE34300.1 - 1.3e-31 109.6 28.7 2e-31 109.0 19.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ICL PF00463.16 EPE34301.1 - 4.4e-119 398.0 0.0 5.3e-119 397.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Aminotran_1_2 PF00155.16 EPE34302.1 - 4.8e-17 61.9 0.0 7.1e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II P22_AR_C PF10548.4 EPE34302.1 - 0.15 11.9 0.8 2.2 8.1 0.2 2.5 3 0 0 3 3 3 0 P22AR C-terminal domain Hydantoinase_B PF02538.9 EPE34303.1 - 1.6e-178 594.2 0.1 2.2e-178 593.7 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EPE34303.1 - 5.6e-93 311.2 0.1 1.5e-92 309.7 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EPE34303.1 - 1.8e-52 177.3 0.7 3.8e-51 173.0 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 EPE34305.1 - 2.8e-17 62.4 65.0 5e-15 55.0 43.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE34305.1 - 1.3e-07 30.2 28.2 1.8e-07 29.7 19.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CFEM PF05730.6 EPE34306.1 - 3.7e-08 33.0 3.9 1.1e-07 31.5 2.7 1.9 1 1 0 1 1 1 1 CFEM domain Pyr_redox_2 PF07992.9 EPE34307.1 - 7.7e-18 65.0 0.1 1.1e-16 61.3 0.0 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE34307.1 - 4.7e-10 39.7 2.1 1.6e-09 38.0 1.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE34307.1 - 7.5e-07 29.4 0.1 0.0017 18.4 0.1 3.4 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE34307.1 - 9.9e-07 27.9 0.2 0.042 12.7 0.1 3.9 4 0 0 4 4 4 2 Lycopene cyclase protein DAO PF01266.19 EPE34307.1 - 4.2e-05 22.6 0.5 0.24 10.2 0.2 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPE34307.1 - 0.00026 20.7 0.8 2.1 8.0 0.0 4.0 5 0 0 5 5 5 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EPE34307.1 - 0.00068 18.3 0.5 2.9 6.4 0.1 3.1 2 1 1 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.9 EPE34307.1 - 0.0013 17.2 0.6 0.19 10.1 0.1 3.6 4 0 0 4 4 4 1 HI0933-like protein K_oxygenase PF13434.1 EPE34307.1 - 0.0014 17.6 0.0 0.0041 16.0 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EPE34307.1 - 0.01 14.7 0.1 0.14 10.9 0.1 2.6 3 0 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.1 EPE34307.1 - 0.013 15.4 0.0 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EPE34307.1 - 0.3 9.8 3.7 0.9 8.3 0.2 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Acetyltransf_1 PF00583.19 EPE34308.1 - 2.4e-07 30.6 0.1 4.7e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE34308.1 - 2.4e-05 24.3 0.0 7.7e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE34308.1 - 0.004 17.0 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE34308.1 - 0.072 13.2 0.0 0.37 10.9 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Thioredoxin_2 PF13098.1 EPE34310.1 - 0.11 12.6 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Gti1_Pac2 PF09729.4 EPE34314.1 - 1.5e-48 164.8 0.2 1.5e-48 164.8 0.2 2.6 2 1 0 2 2 2 1 Gti1/Pac2 family Mcm10 PF09332.6 EPE34314.1 - 6.4 6.0 5.6 9.7 5.4 3.9 1.2 1 0 0 1 1 1 0 Mcm10 replication factor tRNA-synt_2 PF00152.15 EPE34315.1 - 5e-71 239.1 0.0 6.4e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPE34315.1 - 2.4e-07 30.5 0.0 3.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2263 PF10021.4 EPE34316.1 - 9.6e-20 71.0 0.0 1.5e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) RAP1 PF07218.6 EPE34316.1 - 0.99 7.4 7.5 1.3 7.0 5.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HET PF06985.6 EPE34317.1 - 9.6e-36 122.9 2.6 1.6e-35 122.3 1.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EPE34318.1 - 1.5e-23 82.9 2.8 8.5e-11 42.0 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPE34318.1 - 8.2e-20 69.5 9.9 1.6e-07 30.7 0.3 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EPE34318.1 - 1e-18 66.9 7.7 5.1e-07 29.7 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE34318.1 - 8.1e-14 51.6 4.6 8.9e-06 26.0 0.2 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE34318.1 - 1.1e-13 49.9 4.1 0.00044 20.2 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat CorA PF01544.13 EPE34320.1 - 8.2e-11 41.4 0.1 1.3e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4233 PF14017.1 EPE34320.1 - 0.046 13.6 0.7 0.076 12.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) WD40 PF00400.27 EPE34321.1 - 2e-19 68.6 0.7 2.4e-09 36.7 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat EMG1 PF03587.9 EPE34322.1 - 4.9e-78 261.0 0.1 5.7e-78 260.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Rick_17kDa_Anti PF05433.10 EPE34323.1 - 0.28 10.8 12.5 1.2 8.8 8.7 2.1 1 1 0 1 1 1 0 Glycine zipper 2TM domain 4HBT_3 PF13622.1 EPE34324.1 - 9.2e-44 150.0 0.0 1.1e-43 149.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily HET PF06985.6 EPE34326.1 - 5.8e-33 113.9 6.8 5.8e-33 113.9 4.7 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF3402 PF11882.3 EPE34326.1 - 0.0053 15.8 0.0 0.0074 15.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) LCAT PF02450.10 EPE34327.1 - 2.5e-95 319.7 0.0 4.1e-95 319.0 0.0 1.3 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EPE34327.1 - 0.036 13.3 0.1 0.036 13.3 0.0 2.5 3 0 0 3 3 3 0 Lipase (class 2) SKG6 PF08693.5 EPE34328.1 - 0.019 14.2 0.2 0.019 14.2 0.1 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Mid2 PF04478.7 EPE34328.1 - 1.4 8.2 5.2 8 5.8 3.6 2.0 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor VSP PF03302.8 EPE34328.1 - 1.5 7.4 7.3 2.6 6.6 1.4 2.1 1 1 1 2 2 2 0 Giardia variant-specific surface protein VWA_3 PF13768.1 EPE34330.1 - 1.1e-26 93.3 0.0 2.6e-26 92.1 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 EPE34330.1 - 8.8e-18 64.1 0.0 1.7e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EPE34330.1 - 5.6e-11 42.8 0.0 1.1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EPE34330.1 - 7.5e-08 31.7 0.0 1.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EPE34330.1 - 2.2e-05 23.7 0.0 4.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA PF00092.23 EPE34330.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EPE34330.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus AA_permease_2 PF13520.1 EPE34332.1 - 1.8e-54 184.9 50.9 2.2e-54 184.6 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE34332.1 - 1.3e-20 73.2 40.2 1.9e-20 72.6 27.9 1.1 1 0 0 1 1 1 1 Amino acid permease CRPA PF05745.6 EPE34332.1 - 1.8 8.3 5.8 0.82 9.4 0.5 2.7 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) SieB PF14163.1 EPE34332.1 - 5.6 6.5 5.5 13 5.3 0.1 3.0 3 0 0 3 3 3 0 Superinfection exclusion protein B DUF2434 PF10361.4 EPE34333.1 - 2.8e-129 430.4 2.1 3.9e-129 429.9 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) COG5 PF10392.4 EPE34334.1 - 7.2e-41 139.2 0.2 7.2e-41 139.2 0.2 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Big_3_3 PF13750.1 EPE34334.1 - 0.12 11.8 0.3 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) La PF05383.12 EPE34335.1 - 8.3e-11 41.5 0.1 2.1e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 La domain p450 PF00067.17 EPE34336.1 - 3.7e-38 131.2 0.0 4.9e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EPE34337.1 - 1.1e-34 119.7 0.0 1.5e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.15 EPE34338.1 - 2.6e-22 80.1 0.0 3.2e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EPE34338.1 - 1.6e-08 34.7 0.0 1.8e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE34338.1 - 1.7e-05 24.5 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE34338.1 - 0.00043 19.8 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2974 PF11187.3 EPE34338.1 - 0.00088 18.7 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Cutinase PF01083.17 EPE34338.1 - 0.00097 18.9 0.0 0.0018 18.0 0.0 1.4 1 1 0 1 1 1 1 Cutinase Abhydrolase_3 PF07859.8 EPE34338.1 - 0.0016 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EPE34338.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) 2OG-FeII_Oxy PF03171.15 EPE34339.1 - 1e-13 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EPE34339.1 - 0.024 15.1 0.1 0.056 13.9 0.1 1.6 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Acyl_transf_1 PF00698.16 EPE34340.1 - 5.2e-66 223.1 0.0 8e-66 222.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EPE34340.1 - 6.2e-63 212.6 0.8 2.2e-62 210.8 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EPE34340.1 - 1.1e-57 194.6 0.1 2.7e-57 193.3 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EPE34340.1 - 7.4e-56 189.4 0.0 1.1e-55 188.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EPE34340.1 - 1.3e-42 145.5 0.9 5.9e-42 143.4 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPE34340.1 - 4.5e-36 123.3 0.1 1.3e-35 121.8 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EPE34340.1 - 2.7e-18 65.7 0.0 7.4e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EPE34340.1 - 9.9e-17 61.2 0.0 2.7e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE34340.1 - 1e-12 48.0 0.0 2.9e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EPE34340.1 - 5.3e-11 43.5 0.0 1.9e-10 41.6 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EPE34340.1 - 2.5e-08 33.6 0.0 5.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE34340.1 - 4.6e-07 30.4 0.0 1.3e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EPE34340.1 - 1.5e-06 27.9 0.1 4.8e-06 26.3 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EPE34340.1 - 1.6e-06 28.5 0.0 3.7e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EPE34340.1 - 1.1e-05 25.6 0.1 3.9e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EPE34340.1 - 0.00081 18.4 0.1 0.0017 17.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 EPE34340.1 - 0.013 14.9 0.0 0.042 13.3 0.0 1.8 2 0 0 2 2 1 0 Putative methyltransferase Abhydrolase_6 PF12697.2 EPE34340.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ubie_methyltran PF01209.13 EPE34340.1 - 0.083 11.9 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RAP1 PF07218.6 EPE34340.1 - 0.87 7.5 0.1 1.5 6.7 0.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AMP-binding PF00501.23 EPE34341.1 - 0 1560.1 9.2 3.7e-84 282.5 0.1 7.2 6 1 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 EPE34341.1 - 3.3e-262 866.7 9.4 2.4e-45 154.6 0.0 7.4 7 0 0 7 7 7 7 Condensation domain PP-binding PF00550.20 EPE34341.1 - 5.9e-77 253.9 16.1 9.8e-11 41.7 0.1 8.0 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPE34341.1 - 1.5e-30 105.9 0.4 0.00089 20.1 0.0 7.5 7 0 0 7 7 7 6 AMP-binding enzyme C-terminal domain RuvB_C PF05491.8 EPE34341.1 - 0.017 14.7 0.8 21 4.8 0.1 4.3 4 0 0 4 4 4 0 Holliday junction DNA helicase ruvB C-terminus AATase PF07247.7 EPE34341.1 - 0.17 10.3 0.1 4.1 5.8 0.0 2.7 3 0 0 3 3 3 0 Alcohol acetyltransferase RXT2_N PF08595.6 EPE34341.1 - 0.53 10.0 1.5 46 3.7 0.0 3.6 3 0 0 3 3 3 0 RXT2-like, N-terminal Csm1 PF12539.3 EPE34341.1 - 2.3 8.7 3.1 54 4.3 0.0 3.6 4 0 0 4 4 4 0 Chromosome segregation protein Csm1/Pcs1 ABC_tran PF00005.22 EPE34342.1 - 1.2e-47 161.6 0.1 3e-27 95.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPE34342.1 - 1.6e-33 116.2 34.2 2.1e-30 106.1 9.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EPE34342.1 - 1.1e-12 48.6 0.6 0.00069 19.6 0.1 4.6 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EPE34342.1 - 2.8e-10 39.8 6.5 0.0018 17.5 0.2 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPE34342.1 - 4.2e-07 29.4 3.1 0.0088 15.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EPE34342.1 - 1.3e-06 27.4 0.5 0.019 13.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 EPE34342.1 - 2.5e-06 27.5 0.3 0.075 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EPE34342.1 - 4.9e-06 25.8 0.4 0.017 14.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EPE34342.1 - 3.7e-05 23.5 0.2 0.28 11.1 0.0 2.9 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EPE34342.1 - 4e-05 24.4 0.0 0.59 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPE34342.1 - 6.6e-05 23.0 3.6 0.17 12.0 0.3 3.4 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EPE34342.1 - 8.5e-05 22.4 0.0 0.44 10.5 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EPE34342.1 - 0.00015 21.3 2.3 0.062 12.7 0.4 2.8 3 0 0 3 3 3 2 AAA-like domain FtsK_SpoIIIE PF01580.13 EPE34342.1 - 0.00017 21.1 0.9 0.014 14.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EPE34342.1 - 0.00022 21.7 0.9 0.14 12.7 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EPE34342.1 - 0.00059 20.1 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EPE34342.1 - 0.00075 18.6 0.8 0.37 9.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EPE34342.1 - 0.00091 18.6 0.1 0.47 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EPE34342.1 - 0.0011 18.8 1.0 0.22 11.3 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.1 EPE34342.1 - 0.0011 18.8 0.0 0.35 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EPE34342.1 - 0.0013 18.5 6.2 0.016 15.0 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 EPE34342.1 - 0.0019 17.9 1.4 1 9.0 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EPE34342.1 - 0.005 17.1 4.1 0.54 10.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EPE34342.1 - 0.0073 15.9 0.3 0.65 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EPE34342.1 - 0.011 15.4 3.5 0.017 14.8 0.0 2.8 3 1 0 3 3 3 0 Archaeal ATPase AAA_30 PF13604.1 EPE34342.1 - 0.011 15.2 3.9 4.5 6.8 0.1 3.4 3 1 0 3 3 2 0 AAA domain TrwB_AAD_bind PF10412.4 EPE34342.1 - 0.038 12.6 1.7 1.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 EPE34342.1 - 0.039 13.3 2.4 0.19 11.1 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EPE34342.1 - 0.05 13.7 1.7 3.1 7.9 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EPE34342.1 - 0.065 13.0 4.2 0.39 10.4 0.3 2.9 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EPE34342.1 - 0.17 11.4 1.4 4.8 6.7 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Guanylate_kin PF00625.16 EPE34342.1 - 0.2 11.1 0.5 0.6 9.5 0.1 2.1 2 0 0 2 2 2 0 Guanylate kinase Aconitase PF00330.15 EPE34343.1 - 6.6e-58 196.3 0.0 2.2e-37 128.6 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPE34343.1 - 6.8e-16 58.5 0.0 1.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Iso_dh PF00180.15 EPE34344.1 - 1e-115 386.4 0.0 1.2e-115 386.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HMGL-like PF00682.14 EPE34345.1 - 2e-53 181.5 0.0 2.9e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 HMGL-like Aminotran_4 PF01063.14 EPE34346.1 - 4.7e-15 55.6 0.0 6e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV 2OG-FeII_Oxy PF03171.15 EPE34347.1 - 1.5e-18 66.9 0.0 2.7e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EPE34347.1 - 1.5e-17 64.1 0.1 2.6e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal KNOX2 PF03791.8 EPE34347.1 - 0.028 13.7 1.2 0.043 13.0 0.1 1.8 2 0 0 2 2 2 0 KNOX2 domain 2OG-FeII_Oxy PF03171.15 EPE34348.1 - 3.7e-15 56.0 0.1 6.8e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EPE34348.1 - 6.9e-09 36.2 0.0 1.3e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal FlgN PF05130.7 EPE34348.1 - 0.059 13.6 0.0 0.19 12.0 0.0 2.0 2 1 0 2 2 2 0 FlgN protein AMP-binding PF00501.23 EPE34349.1 - 2.9e-68 230.1 0.0 3.4e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE34349.1 - 1.4e-13 51.5 0.0 2.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DIOX_N PF14226.1 EPE34350.1 - 9.7e-20 71.2 0.1 2.2e-19 70.0 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPE34350.1 - 2.2e-18 66.3 0.0 3.8e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.6 EPE34353.1 - 1.1e-23 83.8 0.4 1.1e-23 83.8 0.3 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) zf-H2C2_2 PF13465.1 EPE34356.1 - 6.7e-06 26.1 4.0 6.7e-06 26.1 2.8 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPE34356.1 - 6.8e-06 26.0 12.6 0.001 19.2 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE34356.1 - 2.7e-05 24.2 11.5 0.01 16.1 1.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPE34356.1 - 0.68 9.9 3.7 0.37 10.7 0.6 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger CENP-F_leu_zip PF10473.4 EPE34357.1 - 0.026 14.3 0.2 0.026 14.3 0.1 8.4 6 1 2 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EPE34357.1 - 0.031 13.4 5.9 0.4 9.8 0.2 3.1 4 0 0 4 4 4 0 Reovirus sigma C capsid protein COG5 PF10392.4 EPE34357.1 - 0.11 12.4 19.3 0.33 10.9 0.2 4.4 4 0 0 4 4 4 0 Golgi transport complex subunit 5 DUF641 PF04859.7 EPE34357.1 - 3.8 7.2 28.1 0.49 10.1 2.5 6.1 3 2 3 6 6 6 0 Plant protein of unknown function (DUF641) GST_N PF02798.15 EPE34358.1 - 1e-11 44.8 0.0 1.1e-10 41.4 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPE34358.1 - 3.5e-11 43.1 0.0 6.2e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPE34358.1 - 6.6e-11 42.0 0.0 1.4e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EPE34358.1 - 8.6e-09 35.7 0.2 2.2e-08 34.4 0.2 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPE34358.1 - 5.7e-08 32.6 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPE34358.1 - 1.5e-06 27.9 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Helicase_C_2 PF13307.1 EPE34359.1 - 1.8e-56 190.7 0.0 3.9e-56 189.5 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EPE34359.1 - 9.7e-49 165.0 0.0 1.5e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 AAA_22 PF13401.1 EPE34359.1 - 0.16 12.1 0.9 5.2 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sel1 PF08238.7 EPE34360.1 - 8.8e-13 48.4 21.2 4.6e-06 27.0 0.1 7.2 7 0 0 7 7 7 4 Sel1 repeat TPR_1 PF00515.23 EPE34360.1 - 0.024 14.2 0.1 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPE34360.1 - 0.1 12.2 0.1 0.1 12.2 0.1 2.4 2 0 0 2 2 2 0 TPR repeat TBPIP PF07106.8 EPE34361.1 - 4.8e-27 94.5 0.6 4.8e-27 94.5 0.4 1.9 3 0 0 3 3 3 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EPE34361.1 - 0.0017 18.0 0.7 0.0017 18.0 0.5 2.3 2 1 0 2 2 2 1 Mnd1 family DUF2390 PF09523.5 EPE34361.1 - 0.011 15.9 1.0 0.061 13.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Myelin-PO_C PF10570.4 EPE34361.1 - 0.019 14.9 4.6 0.019 14.9 3.2 3.1 3 0 0 3 3 3 0 Myelin-PO cytoplasmic C-term p65 binding region IncA PF04156.9 EPE34361.1 - 0.37 10.3 3.1 0.77 9.3 2.1 1.4 1 0 0 1 1 1 0 IncA protein zf-CCCH PF00642.19 EPE34362.1 - 3.3e-10 39.4 8.7 2.3e-05 23.9 1.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPE34362.1 - 0.028 14.4 15.8 0.27 11.2 2.9 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Evr1_Alr PF04777.8 EPE34363.1 - 2.3e-27 94.6 1.3 2.3e-27 94.6 0.9 1.6 2 0 0 2 2 2 1 Erv1 / Alr family HEM4 PF02602.10 EPE34364.1 - 4.1e-40 137.4 0.0 5.3e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD IncA PF04156.9 EPE34365.1 - 1.9 8.0 5.7 0.38 10.3 1.1 1.7 2 0 0 2 2 2 0 IncA protein NfeD PF01957.13 EPE34366.1 - 0.00082 19.5 0.1 0.23 11.6 0.0 2.0 1 1 1 2 2 2 2 NfeD-like C-terminal, partner-binding DUF1183 PF06682.7 EPE34366.1 - 0.0016 18.0 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Herpes_gE PF02480.11 EPE34366.1 - 0.0099 14.1 0.0 0.012 13.9 0.0 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF3377 PF11857.3 EPE34366.1 - 0.013 15.1 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF1191 PF06697.7 EPE34366.1 - 0.018 13.8 0.3 0.02 13.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TRP PF06011.7 EPE34366.1 - 0.028 13.0 0.0 0.034 12.7 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Syndecan PF01034.15 EPE34366.1 - 0.043 13.4 0.6 0.07 12.7 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain P12 PF12669.2 EPE34366.1 - 0.046 13.9 2.8 0.14 12.3 2.0 1.9 1 1 0 1 1 1 0 Virus attachment protein p12 family LRR19-TM PF15176.1 EPE34366.1 - 0.083 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF2668 PF10873.3 EPE34366.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) HAMP PF00672.20 EPE34366.1 - 1.7 8.9 4.2 2.6 8.3 2.9 1.3 1 0 0 1 1 1 0 HAMP domain BofA PF07441.6 EPE34367.1 - 0.028 14.4 0.8 0.028 14.4 0.6 1.9 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA DUF2142 PF09913.4 EPE34367.1 - 0.033 12.8 0.3 0.034 12.8 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) YibE_F PF07907.6 EPE34367.1 - 0.034 13.3 1.2 0.041 13.0 0.8 1.2 1 0 0 1 1 1 0 YibE/F-like protein DUF3147 PF11345.3 EPE34367.1 - 0.044 13.7 0.0 0.055 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) CD34_antigen PF06365.7 EPE34367.1 - 0.091 12.3 0.1 0.091 12.3 0.0 1.5 2 0 0 2 2 2 0 CD34/Podocalyxin family 7TM_GPCR_Srh PF10318.4 EPE34367.1 - 0.18 10.5 2.7 0.54 9.0 1.9 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF4389 PF14333.1 EPE34367.1 - 0.2 11.3 0.8 5.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Flavi_NS2B PF01002.14 EPE34367.1 - 0.35 10.4 1.8 0.67 9.5 0.1 1.9 1 1 0 2 2 2 0 Flavivirus non-structural protein NS2B Chitin_synth_2 PF03142.10 EPE34367.1 - 1.5 7.0 3.7 1.7 6.9 2.6 1.0 1 0 0 1 1 1 0 Chitin synthase TPR_11 PF13414.1 EPE34368.1 - 5.7e-13 48.3 2.3 2.9e-06 26.8 0.1 2.8 2 0 0 2 2 2 2 TPR repeat SET PF00856.23 EPE34368.1 - 1.2e-10 41.9 0.1 5.1e-09 36.6 0.1 2.7 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.12 EPE34368.1 - 2e-09 36.6 8.8 3.3e-05 23.4 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPE34368.1 - 9.7e-07 28.1 2.3 0.0014 18.1 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPE34368.1 - 0.00011 22.0 4.0 0.0026 17.6 0.3 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPE34368.1 - 0.0022 18.5 0.2 1.8 9.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPE34368.1 - 0.0078 16.7 0.5 0.11 13.1 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPE34368.1 - 0.019 14.7 1.6 0.19 11.5 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPE34368.1 - 0.17 12.2 0.4 30 5.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPE34368.1 - 0.24 11.6 2.1 18 5.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CorA PF01544.13 EPE34369.1 - 5.8e-09 35.3 3.0 1.3e-08 34.2 0.0 2.6 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein Aldo_ket_red PF00248.16 EPE34370.1 - 2.3e-44 151.3 0.0 2.7e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_6 PF13516.1 EPE34371.1 - 2.6e-14 51.6 8.3 0.21 11.7 0.0 7.5 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.2 EPE34371.1 - 6.6e-06 25.6 2.9 1.6 8.3 0.0 4.4 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) DUF1480 PF07351.8 EPE34371.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) SSP160 PF06933.6 EPE34372.1 - 5.7 4.7 15.2 8.6 4.1 10.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Amidoligase_2 PF12224.3 EPE34373.1 - 2.3e-35 122.4 0.9 1.7e-34 119.5 0.6 2.0 1 1 0 1 1 1 1 Putative amidoligase enzyme WD40 PF00400.27 EPE34374.1 - 3.9e-07 29.6 1.8 0.011 15.5 0.0 4.9 6 0 0 6 6 6 3 WD domain, G-beta repeat GARS_A PF01071.14 EPE34374.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF1917 PF08939.5 EPE34375.1 - 1.1e-65 221.8 0.4 1.3e-65 221.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Succ_CoA_lig PF13607.1 EPE34375.1 - 0.054 13.1 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Phlebovirus_NSM PF07246.6 EPE34375.1 - 0.089 11.9 0.2 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Apolipo_F PF15148.1 EPE34375.1 - 0.1 11.9 1.1 0.16 11.2 0.3 1.6 2 0 0 2 2 2 0 Apolipoprotein F Acetyltransf_1 PF00583.19 EPE34376.1 - 1.4e-05 24.9 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPE34376.1 - 0.0021 17.7 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EPE34376.1 - 0.086 12.7 0.0 0.099 12.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPE34376.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE34376.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TLD PF07534.11 EPE34377.1 - 3.1e-26 92.0 0.0 4.7e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 TLD HD PF01966.17 EPE34378.1 - 0.072 13.0 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 HD domain Ribosomal_L18e PF00828.14 EPE34379.1 - 9.1e-34 116.6 0.0 1.2e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Pkinase PF00069.20 EPE34380.1 - 7e-45 153.2 0.0 2.3e-41 141.6 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE34380.1 - 9.1e-15 54.4 0.0 2.2e-08 33.5 0.0 3.4 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 EPE34380.1 - 1.8e-05 24.5 0.1 0.026 14.2 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EPE34380.1 - 8.5e-05 21.6 0.0 0.21 10.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EPE34380.1 - 0.066 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CENP-B_dimeris PF09026.5 EPE34380.1 - 1.6 9.0 10.5 18 5.6 6.4 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cnd1_N PF12922.2 EPE34381.1 - 3.7e-59 199.1 0.2 1.8e-58 196.9 0.1 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 EPE34381.1 - 2.3e-54 183.9 6.0 1.6e-50 171.4 1.2 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EPE34381.1 - 9.9e-12 44.9 4.3 8.9e-06 25.9 0.0 5.7 6 2 1 7 7 7 2 HEAT repeats HEAT PF02985.17 EPE34381.1 - 8.4e-07 28.5 10.5 0.054 13.5 0.0 6.7 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 EPE34381.1 - 8e-05 23.0 7.4 0.16 12.4 0.0 5.7 5 1 1 6 6 6 1 HEAT-like repeat VHS PF00790.14 EPE34381.1 - 0.013 15.1 0.6 1.3 8.6 0.0 3.5 3 0 0 3 3 3 0 VHS domain DUF2435 PF10363.4 EPE34381.1 - 0.019 14.8 0.0 7.8 6.4 0.0 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 EPE34381.1 - 0.02 14.8 0.1 7.7 6.5 0.1 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion U3_snoRNA_assoc PF08297.6 EPE34382.1 - 0.061 13.5 0.9 0.073 13.3 0.6 1.2 1 0 0 1 1 1 0 U3 snoRNA associated Helitron_like_N PF14214.1 EPE34382.1 - 0.065 12.9 1.0 0.077 12.7 0.7 1.0 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus DUF3619 PF12279.3 EPE34382.1 - 0.28 11.2 5.8 0.35 10.9 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) HET PF06985.6 EPE34384.1 - 3.4e-30 105.0 0.3 6.8e-30 104.0 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Podoplanin PF05808.6 EPE34385.1 - 0.072 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Podoplanin SAC3_GANP PF03399.11 EPE34387.1 - 1.3e-21 77.1 0.0 1.6e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPE34387.1 - 2.6e-19 69.3 0.0 3.7e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Coatomer_WDAD PF04053.9 EPE34388.1 - 6.2e-149 496.5 0.0 9.4e-149 495.9 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 EPE34388.1 - 1.5e-48 160.9 16.8 6.7e-09 35.2 0.0 8.1 9 0 0 9 9 9 6 WD domain, G-beta repeat Clathrin PF00637.15 EPE34388.1 - 0.0051 16.4 0.3 0.042 13.4 0.0 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS Nup160 PF11715.3 EPE34388.1 - 0.0053 14.9 7.6 0.18 9.8 0.1 3.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 UDP-g_GGTase PF06427.6 EPE34389.1 - 7.1e-64 214.9 0.1 4.2e-63 212.4 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EPE34389.1 - 0.0016 17.8 0.0 0.0039 16.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 MFS_1 PF07690.11 EPE34391.1 - 3.4e-25 88.5 20.1 3.4e-25 88.5 14.0 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EPE34391.1 - 1e-05 23.9 4.8 1.6e-05 23.3 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE34396.1 - 6.4e-70 235.9 26.5 7.3e-70 235.7 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE34396.1 - 5.5e-09 35.2 41.2 1.6e-07 30.3 23.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE34396.1 - 1.2 7.4 36.4 0.0068 14.8 5.5 3.4 3 1 1 4 4 4 0 MFS/sugar transport protein RHH_2 PF03693.9 EPE34399.1 - 0.066 13.3 0.1 0.086 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0156) mRNA_stabil PF13929.1 EPE34399.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 mRNA stabilisation Hemerythrin PF01814.18 EPE34403.1 - 1e-10 41.8 0.4 1.3e-10 41.4 0.3 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Sugar_tr PF00083.19 EPE34404.1 - 5.5e-42 143.8 23.9 8e-42 143.3 16.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE34404.1 - 3.1e-15 55.7 26.3 3.1e-15 55.7 18.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Ank_2 PF12796.2 EPE34405.1 - 8.1e-05 22.8 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE34405.1 - 0.00019 21.0 0.0 0.002 17.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EPE34405.1 - 0.0048 17.3 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE34405.1 - 0.008 16.4 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE34405.1 - 0.0084 16.2 0.0 0.08 13.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat CEP44 PF15007.1 EPE34405.1 - 0.033 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 YicC_N PF03755.8 EPE34405.1 - 0.086 12.7 3.7 0.16 11.8 2.5 1.4 1 0 0 1 1 1 0 YicC-like family, N-terminal region SYS1 PF09801.4 EPE34406.1 - 2.6e-53 179.9 9.2 2.9e-53 179.7 6.4 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COX6B PF02297.12 EPE34407.1 - 4.5e-25 87.4 3.5 5.3e-25 87.2 2.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EPE34407.1 - 0.11 12.6 0.6 0.18 11.8 0.4 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 HET PF06985.6 EPE34410.1 - 1.2e-19 70.8 0.0 2.4e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-Sec23_Sec24 PF04810.10 EPE34412.1 - 0.12 11.9 1.9 0.45 10.1 0.2 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-Di19 PF05605.7 EPE34412.1 - 3.1 8.0 6.9 42 4.3 0.1 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Glyco_hydro_28 PF00295.12 EPE34413.1 - 2.1e-83 279.9 14.8 2.6e-83 279.6 10.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EPE34413.1 - 0.0015 18.3 33.1 0.0015 18.3 23.0 2.9 1 1 1 2 2 2 2 Right handed beta helix region DUF3431 PF11913.3 EPE34414.1 - 2.3e-54 184.1 0.2 2.8e-54 183.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Bap31 PF05529.7 EPE34416.1 - 0.00069 19.1 0.1 0.0014 18.1 0.1 1.4 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Oxidored_q1 PF00361.15 EPE34416.1 - 0.011 14.9 0.9 0.011 14.9 0.6 1.8 2 0 0 2 2 2 0 NADH-Ubiquinone/plastoquinone (complex I), various chains Mlo PF03094.10 EPE34416.1 - 0.025 12.6 0.2 0.13 10.3 0.1 1.9 2 0 0 2 2 2 0 Mlo family DUF2721 PF11026.3 EPE34416.1 - 0.025 14.1 1.1 2 8.0 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Virul_fac_BrkB PF03631.10 EPE34416.1 - 0.11 11.8 9.1 0.029 13.7 1.9 2.2 2 1 0 2 2 2 0 Virulence factor BrkB DUF4131 PF13567.1 EPE34416.1 - 0.43 9.9 11.0 0.22 10.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Glyco_hydro_47 PF01532.15 EPE34417.1 - 3.5e-130 434.7 0.0 4.3e-130 434.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SBF PF01758.11 EPE34417.1 - 0.029 13.7 5.0 0.08 12.3 3.4 1.7 1 0 0 1 1 1 0 Sodium Bile acid symporter family TMEMspv1-c74-12 PF11044.3 EPE34421.1 - 0.035 13.6 0.1 0.066 12.7 0.1 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Sec23_trunk PF04811.10 EPE34422.1 - 7.2e-68 228.5 0.0 1e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPE34422.1 - 3.3e-23 81.0 0.0 4.9e-22 77.3 0.0 2.5 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPE34422.1 - 3.7e-19 69.0 0.1 7.2e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPE34422.1 - 6.4e-18 64.0 5.4 1.1e-17 63.2 3.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPE34422.1 - 1.1e-07 31.3 0.0 2.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Pkinase PF00069.20 EPE34423.1 - 2.3e-73 246.5 0.0 3.2e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE34423.1 - 5e-32 110.9 0.0 7.6e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE34423.1 - 0.00057 18.9 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPE34423.1 - 0.0026 16.8 0.1 0.0046 16.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE34423.1 - 0.0055 16.4 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPE34423.1 - 0.059 12.2 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF1767 PF08585.7 EPE34424.1 - 5.2e-08 33.0 0.0 1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Vps51 PF08700.6 EPE34425.1 - 6.1e-22 77.2 0.0 1e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 NYD-SP28_assoc PF14775.1 EPE34425.1 - 0.063 12.9 0.2 0.063 12.9 0.1 1.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain COG5 PF10392.4 EPE34425.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 NIF3 PF01784.13 EPE34426.1 - 1.2e-60 205.0 0.0 1.5e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF3783 PF12646.2 EPE34426.1 - 0.021 14.5 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) BolA PF01722.13 EPE34427.1 - 2.2e-20 72.3 0.0 2.8e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein MAGUK_N_PEST PF10608.4 EPE34427.1 - 0.07 13.5 0.1 0.11 12.9 0.1 1.3 1 1 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Adaptin_N PF01602.15 EPE34428.1 - 4.6e-151 503.7 4.2 6.4e-151 503.2 2.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EPE34428.1 - 2.4e-25 89.4 0.4 1.2e-24 87.1 0.0 2.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EPE34428.1 - 4.5e-18 65.3 0.7 1.5e-06 28.3 0.0 5.1 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.17 EPE34428.1 - 1.5e-11 43.3 3.4 0.016 15.2 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EPE34428.1 - 0.0002 21.7 1.6 0.89 10.1 0.0 5.4 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 EPE34428.1 - 0.0011 18.3 0.1 1.7 7.9 0.0 3.4 2 1 1 3 3 3 2 CLASP N terminal Atx10homo_assoc PF09759.4 EPE34428.1 - 0.0054 16.4 0.0 0.088 12.5 0.0 2.6 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF3554 PF12074.3 EPE34428.1 - 0.0068 15.8 0.2 0.66 9.3 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3554) Cohesin_HEAT PF12765.2 EPE34428.1 - 0.024 14.6 0.1 10 6.2 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Fungal_trans_2 PF11951.3 EPE34429.1 - 2.6e-11 42.7 0.1 1.3e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE34429.1 - 1.8e-05 24.5 9.2 4.3e-05 23.3 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NusB PF01029.13 EPE34429.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 NusB family zf-C2H2_4 PF13894.1 EPE34430.1 - 0.00068 19.7 0.7 0.00068 19.7 0.5 3.5 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE34430.1 - 0.004 17.4 1.1 0.004 17.4 0.7 3.7 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EPE34430.1 - 0.12 12.7 0.2 0.12 12.7 0.2 3.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Xpo1 PF08389.7 EPE34431.1 - 1.8e-07 31.1 5.0 2.3e-05 24.3 0.1 3.9 3 0 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.14 EPE34431.1 - 0.0027 17.5 0.3 0.021 14.7 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cellulase PF00150.13 EPE34432.1 - 4.3e-15 55.6 2.6 6.2e-10 38.7 1.5 2.7 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EPE34432.1 - 2.8e-05 23.4 1.0 0.062 12.4 0.1 2.2 2 0 0 2 2 2 2 Beta-galactosidase TPR_11 PF13414.1 EPE34433.1 - 7.8e-44 147.1 35.9 1.4e-06 27.8 0.0 12.9 11 3 2 13 13 13 10 TPR repeat TPR_16 PF13432.1 EPE34433.1 - 2.7e-33 113.9 46.7 1e-07 32.4 3.0 12.5 11 3 2 13 13 11 7 Tetratricopeptide repeat TPR_14 PF13428.1 EPE34433.1 - 3.9e-28 95.3 23.6 0.0065 17.0 0.2 14.1 10 5 4 14 14 14 5 Tetratricopeptide repeat TPR_17 PF13431.1 EPE34433.1 - 6e-28 94.6 19.3 0.021 15.0 0.0 16.5 17 1 1 18 18 17 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPE34433.1 - 7.7e-27 93.4 28.5 8.6e-06 26.0 4.7 11.6 9 2 2 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.23 EPE34433.1 - 9.1e-27 91.5 33.0 0.00041 19.8 0.0 13.1 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_2 PF07719.12 EPE34433.1 - 4.2e-26 88.7 46.4 0.002 17.8 0.0 16.1 15 1 1 16 16 15 8 Tetratricopeptide repeat TPR_8 PF13181.1 EPE34433.1 - 1.8e-23 80.5 15.1 0.024 14.3 0.0 11.4 10 3 2 12 12 11 7 Tetratricopeptide repeat TPR_12 PF13424.1 EPE34433.1 - 1.2e-15 57.1 39.2 1.3e-05 25.0 0.1 11.3 8 5 4 12 12 11 8 Tetratricopeptide repeat TPR_6 PF13174.1 EPE34433.1 - 1.5e-11 43.9 25.8 0.038 14.4 0.0 13.9 15 1 0 15 15 15 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPE34433.1 - 1.9e-11 42.8 24.0 0.014 15.1 0.0 12.7 14 1 0 14 14 13 3 Tetratricopeptide repeat Apc3 PF12895.2 EPE34433.1 - 2.6e-11 43.4 20.0 0.015 15.3 0.0 7.8 7 1 1 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EPE34433.1 - 1.7e-09 37.3 7.1 0.0024 17.6 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat ChAPs PF09295.5 EPE34433.1 - 0.0022 16.8 4.1 6 5.5 0.0 5.1 5 1 1 6 6 6 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.1 EPE34433.1 - 0.0046 16.8 7.7 3.6 7.5 0.3 6.9 7 1 1 8 8 8 1 Fis1 C-terminal tetratricopeptide repeat CytochromB561_N PF09786.4 EPE34433.1 - 0.017 13.5 0.1 0.029 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF2371 PF10177.4 EPE34434.1 - 0.1 12.4 0.4 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Sec61_beta PF03911.11 EPE34434.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.6 3 0 0 3 3 3 0 Sec61beta family Cation_ATPase_C PF00689.16 EPE34435.1 - 0.0023 17.4 1.4 0.0028 17.2 1.0 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF4396 PF14342.1 EPE34435.1 - 0.078 13.0 1.9 0.096 12.7 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) Ribosomal_S17 PF00366.15 EPE34436.1 - 8.1e-06 25.7 1.1 2.1e-05 24.4 0.7 1.7 1 0 0 1 1 1 1 Ribosomal protein S17 PhyH PF05721.8 EPE34436.1 - 0.061 13.3 0.0 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) DUF3632 PF12311.3 EPE34437.1 - 1.4e-26 93.4 0.9 2.2e-26 92.7 0.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) Pec_lyase_C PF00544.14 EPE34438.1 - 1.7e-16 60.3 1.9 4.3e-16 58.9 1.3 1.7 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EPE34438.1 - 6.9e-05 22.6 7.5 0.012 15.3 6.0 2.3 1 1 1 2 2 2 2 Right handed beta helix region CompInhib_SCIN PF11546.3 EPE34439.1 - 4.1e-05 23.3 0.1 0.29 10.9 0.0 2.8 1 1 1 3 3 3 2 Staphylococcal complement inhibitor SCIN Acetyltransf_1 PF00583.19 EPE34439.1 - 0.002 18.1 0.0 1.4 9.0 0.0 2.8 3 0 0 3 3 3 2 Acetyltransferase (GNAT) family Telethonin PF09470.5 EPE34439.1 - 0.0036 16.7 0.0 1.3 8.4 0.0 2.8 2 1 1 3 3 3 2 Telethonin protein CAAP1 PF15335.1 EPE34439.1 - 0.06 13.5 0.0 19 5.5 0.0 3.1 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 Maff2 PF12750.2 EPE34439.1 - 0.32 10.5 1.5 1.1 8.8 0.0 2.5 3 0 0 3 3 3 0 Maff2 family PAP2 PF01569.16 EPE34440.1 - 4.9e-21 74.7 4.2 4.9e-21 74.7 2.9 1.8 2 0 0 2 2 2 1 PAP2 superfamily HET PF06985.6 EPE34442.1 - 1.3e-21 77.2 1.3 1.4e-21 77.1 0.1 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Asp PF00026.18 EPE34443.1 - 8.1e-43 146.8 0.2 1.1e-42 146.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EPE34443.1 - 6.5e-07 29.7 1.6 0.00031 21.1 0.6 3.6 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EPE34443.1 - 0.00051 19.8 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EPE34443.1 - 0.0026 17.6 0.0 0.035 14.0 0.0 2.6 2 1 1 3 3 3 1 Retroviral aspartyl protease TAXi_C PF14541.1 EPE34443.1 - 0.0033 16.9 0.0 0.0071 15.9 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Fungal_trans_2 PF11951.3 EPE34444.1 - 1.2e-09 37.2 3.9 1.7e-08 33.4 2.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE34444.1 - 1.7e-07 30.9 13.6 7.1e-07 29.0 6.5 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_20 PF00982.16 EPE34445.1 - 4.9e-195 648.5 0.0 5.8e-195 648.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EPE34445.1 - 0.081 12.4 0.2 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain DUF3748 PF12566.3 EPE34445.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) MDH PF02315.11 EPE34446.1 - 0.24 11.3 3.2 0.87 9.5 0.1 2.3 2 1 0 2 2 2 0 Methanol dehydrogenase beta subunit CstA PF02554.9 EPE34449.1 - 0.0037 15.9 6.5 0.0037 15.9 4.5 1.7 1 1 1 2 2 2 2 Carbon starvation protein CstA DUF1673 PF07895.6 EPE34449.1 - 2.3 7.6 6.9 4.6 6.7 4.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) MFS_1 PF07690.11 EPE34450.1 - 3e-16 59.0 60.7 1.9e-15 56.4 19.5 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Peptidase_M50 PF02163.17 EPE34450.1 - 0.011 14.6 0.0 0.086 11.7 0.0 2.3 1 1 0 1 1 1 0 Peptidase family M50 DUF4066 PF13278.1 EPE34451.1 - 1.9e-24 85.8 0.0 2.2e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EPE34451.1 - 2.5e-13 49.7 0.0 3.2e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Yeast-kill-tox PF09207.6 EPE34451.1 - 0.053 13.9 0.1 0.097 13.1 0.1 1.4 1 0 0 1 1 1 0 Yeast killer toxin GATase PF00117.23 EPE34451.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I AATase PF07247.7 EPE34452.1 - 1.1e-07 30.8 0.0 2.1e-07 29.8 0.0 1.4 2 0 0 2 2 2 1 Alcohol acetyltransferase Condensation PF00668.15 EPE34452.1 - 4.4e-07 29.0 0.5 7.6e-07 28.2 0.3 1.3 1 0 0 1 1 1 1 Condensation domain Transferase PF02458.10 EPE34452.1 - 0.1 10.9 0.9 1.1 7.5 0.0 2.2 3 0 0 3 3 3 0 Transferase family Abhydrolase_3 PF07859.8 EPE34453.1 - 1.9e-45 155.0 0.0 2.6e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EPE34453.1 - 6.4e-14 51.5 0.0 3.2e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EPE34453.1 - 5.5e-07 29.6 0.0 1.7e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE34453.1 - 7.1e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE34453.1 - 0.0056 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EPE34453.1 - 0.025 13.8 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.13 EPE34453.1 - 0.048 12.9 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DIT1_PvcA PF05141.7 EPE34454.1 - 2.4e-85 286.2 0.0 3.7e-85 285.6 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein ABC_tran PF00005.22 EPE34454.1 - 1.6e-09 38.1 0.7 3.1e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EPE34454.1 - 0.022 13.9 0.0 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AMP-binding PF00501.23 EPE34455.1 - 2.8e-25 88.5 0.0 6.5e-25 87.3 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Transferase PF02458.10 EPE34455.1 - 5.7e-13 48.0 0.0 1.5e-08 33.5 0.0 2.3 1 1 1 2 2 2 2 Transferase family PP-binding PF00550.20 EPE34455.1 - 6.2e-10 39.1 0.1 2.8e-09 37.0 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site MFS_1 PF07690.11 EPE34456.1 - 7.9e-39 133.3 50.4 1.4e-38 132.5 33.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE34456.1 - 4.1e-11 41.7 8.2 4.1e-11 41.7 5.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE34456.1 - 5.1e-10 38.5 7.1 5.1e-10 38.5 4.9 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter AAA PF00004.24 EPE34457.1 - 2e-38 131.5 0.0 3.7e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE34457.1 - 7.2e-06 26.1 0.1 0.00012 22.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.5 EPE34457.1 - 2e-05 24.3 0.0 0.00043 20.1 0.0 3.0 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 EPE34457.1 - 6.6e-05 22.0 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPE34457.1 - 9.5e-05 22.4 0.7 0.0032 17.4 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EPE34457.1 - 0.00056 18.7 0.2 0.0016 17.2 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 EPE34457.1 - 0.0016 18.1 0.0 0.0057 16.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EPE34457.1 - 0.0018 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EPE34457.1 - 0.0031 17.4 0.0 0.0089 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EPE34457.1 - 0.0042 16.2 0.1 0.009 15.1 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EPE34457.1 - 0.0062 16.2 0.1 0.029 14.1 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EPE34457.1 - 0.011 15.6 1.4 0.036 13.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EPE34457.1 - 0.011 14.6 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EPE34457.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPE34457.1 - 0.043 13.7 0.7 0.2 11.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EPE34457.1 - 0.043 13.2 0.1 0.25 10.7 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EPE34457.1 - 0.044 13.3 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPE34457.1 - 0.048 14.4 0.1 0.16 12.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EPE34457.1 - 0.15 11.5 0.0 0.6 9.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 EPE34457.1 - 0.17 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 EPE34457.1 - 0.23 11.1 0.5 0.59 9.7 0.0 1.9 2 0 0 2 2 1 0 Archaeal ATPase Mito_carr PF00153.22 EPE34458.1 - 1.4e-73 242.6 4.1 2.7e-25 87.8 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein APG9 PF04109.11 EPE34459.1 - 6.9e-144 479.3 1.4 8.8e-144 478.9 1.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 COG6 PF06419.6 EPE34460.1 - 1.7e-233 776.3 4.3 1.9e-233 776.1 3.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 GAS PF13851.1 EPE34460.1 - 0.0057 15.8 1.6 0.016 14.4 1.1 1.7 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding COG2 PF06148.6 EPE34460.1 - 0.04 13.7 1.9 0.14 11.9 0.4 2.6 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ACCA PF03255.9 EPE34460.1 - 0.098 12.2 0.3 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ApbA_C PF08546.6 EPE34461.1 - 3.8e-37 127.0 0.1 1.4e-36 125.2 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EPE34461.1 - 3.1e-21 75.3 0.1 5e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Fungal_trans_2 PF11951.3 EPE34461.1 - 0.045 12.3 0.0 0.067 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain NmrA PF05368.8 EPE34462.1 - 1.9e-27 96.0 0.0 4.6e-27 94.7 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE34462.1 - 0.0017 18.3 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE34462.1 - 0.0022 16.7 0.0 0.003 16.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EPE34462.1 - 0.024 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain His_Phos_1 PF00300.17 EPE34463.1 - 4.1e-20 72.4 0.0 4.9e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Chromate_transp PF02417.10 EPE34464.1 - 1e-49 168.3 31.9 2.2e-26 92.4 8.0 2.6 3 0 0 3 3 3 2 Chromate transporter p450 PF00067.17 EPE34465.1 - 1.4e-07 30.4 0.0 1.6e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.14 EPE34467.1 - 4.1e-53 179.8 0.0 5.1e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE34467.1 - 4.7e-26 91.6 0.0 6.3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPE34467.1 - 2.4e-15 56.1 0.0 5.3e-14 51.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EPE34467.1 - 3.7e-12 46.6 0.0 5.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPE34467.1 - 1.7e-10 40.2 0.0 7.5e-10 38.1 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EPE34467.1 - 4.6e-08 32.2 0.0 1.9e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EPE34467.1 - 1.4e-07 31.6 0.0 7.4e-07 29.2 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE34467.1 - 2.2e-05 24.1 1.0 0.00035 20.2 0.1 2.8 2 1 0 2 2 2 1 KR domain NmrA PF05368.8 EPE34467.1 - 0.014 14.6 0.0 0.03 13.5 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family Rft-1 PF04506.8 EPE34468.1 - 7e-47 160.0 4.0 1.8e-46 158.7 2.8 1.6 1 1 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 EPE34468.1 - 0.0013 18.0 11.8 0.01 15.1 1.6 3.0 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein DUF485 PF04341.7 EPE34468.1 - 0.052 13.2 3.9 1 9.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DEAD PF00270.24 EPE34469.1 - 4.8e-47 159.5 0.0 1.6e-44 151.3 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE34469.1 - 9.6e-29 99.0 0.0 1.4e-27 95.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE34469.1 - 1.7e-07 31.2 0.5 1.1e-06 28.6 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EPE34469.1 - 0.0098 14.9 0.0 0.0098 14.9 0.0 2.8 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EPE34469.1 - 0.069 11.5 0.0 0.22 9.8 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EPE34469.1 - 0.12 12.5 0.9 1.5 8.9 0.4 2.7 2 1 0 2 2 2 0 AAA domain NifU_N PF01592.11 EPE34470.1 - 2.6e-51 172.8 0.0 3.4e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain UCH PF00443.24 EPE34471.1 - 3.8e-42 144.2 0.0 5.4e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPE34471.1 - 6.2e-22 77.4 14.4 2.7e-18 65.8 1.1 3.2 3 1 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EPE34471.1 - 8.4e-22 77.9 0.0 1.2e-20 74.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EPE34471.1 - 1.3e-21 75.7 0.0 6.1e-10 38.6 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.1 EPE34471.1 - 0.074 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Prim_Zn_Ribbon PF08273.7 EPE34471.1 - 1.4 9.0 6.4 4.3 7.5 0.1 3.4 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase Fungal_trans PF04082.13 EPE34472.1 - 3.1e-13 49.1 1.6 1e-12 47.5 1.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPE34472.1 - 2.8e-05 24.1 12.7 0.0092 16.2 1.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE34472.1 - 9.8e-05 22.4 12.8 0.0014 18.8 2.3 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger Peptidase_M20 PF01546.23 EPE34473.1 - 1e-26 93.5 0.0 3.1e-26 92.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPE34473.1 - 1.6e-15 56.7 0.0 2.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain CBM_48 PF02922.13 EPE34474.1 - 0.049 13.6 0.2 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) cNMP_binding PF00027.24 EPE34475.1 - 1.7e-40 136.7 0.0 1e-20 73.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain BCAS2 PF05700.6 EPE34476.1 - 3.8e-47 160.6 0.0 4.1e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ceramidase_alk PF04734.8 EPE34477.1 - 5.6e-280 930.0 0.0 6.3e-280 929.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase RNA_pol_Rpb1_5 PF04998.12 EPE34478.1 - 1.2e-85 287.1 0.1 2.4e-85 286.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPE34478.1 - 2.3e-69 232.5 0.3 1.1e-68 230.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 EPE34478.1 - 1.4e-59 202.0 0.8 2.4e-54 184.8 0.3 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 EPE34478.1 - 3.9e-39 133.9 0.0 1e-38 132.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EPE34478.1 - 1.4e-26 92.3 1.5 4.2e-26 90.7 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DUF2296 PF10058.4 EPE34478.1 - 0.081 12.6 0.3 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) NIF PF03031.13 EPE34479.1 - 2.5e-51 173.4 0.0 4e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.12 EPE34480.1 - 2.8e-58 197.1 7.7 1.9e-31 109.0 0.0 2.8 2 1 0 2 2 2 2 Initiation factor 2 subunit family Ribosomal_S10 PF00338.17 EPE34480.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e DUF4477 PF14780.1 EPE34480.1 - 0.16 11.2 0.2 0.37 10.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) DUF4646 PF15496.1 EPE34481.1 - 0.038 14.0 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) CAF-1_p150 PF11600.3 EPE34482.1 - 0.52 9.6 28.5 0.051 12.9 15.6 2.2 2 1 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RP-C_C PF11800.3 EPE34482.1 - 2.4 7.8 12.5 0.34 10.5 4.2 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region SR-25 PF10500.4 EPE34482.1 - 7.5 5.9 34.8 0.75 9.2 8.0 2.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein adh_short PF00106.20 EPE34483.1 - 2.1e-23 83.0 0.1 8.2e-23 81.1 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE34483.1 - 2.9e-20 73.0 0.2 4.9e-20 72.3 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE34483.1 - 3.7e-11 43.0 0.6 1.1e-09 38.1 0.4 2.2 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EPE34483.1 - 0.00082 18.5 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EPE34483.1 - 0.0031 16.9 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE34483.1 - 0.012 15.6 0.3 0.06 13.3 0.2 2.1 1 1 0 1 1 1 0 NADH(P)-binding Pyr_redox PF00070.22 EPE34483.1 - 0.031 14.6 0.4 0.1 13.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE34483.1 - 0.032 12.7 1.0 0.94 7.8 0.3 2.3 1 1 1 2 2 2 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 EPE34483.1 - 0.08 12.6 0.0 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RAMP4 PF06624.7 EPE34483.1 - 0.097 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 3HCDH_N PF02737.13 EPE34483.1 - 0.16 11.6 0.6 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1712 PF08217.6 EPE34484.1 - 5e-16 58.0 0.0 2e-14 52.8 0.0 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Peptidase_U35_2 PF14550.1 EPE34484.1 - 0.021 14.4 1.0 0.11 12.1 0.1 2.4 3 0 0 3 3 3 0 Putative phage protease XkdF Formyl_trans_N PF00551.14 EPE34485.1 - 1e-26 93.5 0.0 1.6e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EPE34485.1 - 0.0013 18.7 0.8 0.016 15.2 0.6 2.3 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain CIAPIN1 PF05093.8 EPE34486.1 - 1.9e-34 117.6 3.1 3e-34 117.1 2.1 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Dehydrin PF00257.14 EPE34487.1 - 0.034 14.4 2.9 0.067 13.5 2.0 1.6 1 1 0 1 1 1 0 Dehydrin HABP4_PAI-RBP1 PF04774.10 EPE34487.1 - 0.5 10.8 7.0 1.1 9.7 4.8 1.6 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family adh_short PF00106.20 EPE34488.1 - 2.3e-21 76.4 0.1 3.4e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE34488.1 - 2.6e-21 76.5 0.0 3.1e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE34488.1 - 9.9e-10 38.3 0.0 1.4e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE34488.1 - 0.057 12.8 0.2 0.18 11.1 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ICE2 PF08426.5 EPE34490.1 - 3.7e-115 384.8 3.6 4e-115 384.7 2.5 1.0 1 0 0 1 1 1 1 ICE2 DUF3074 PF11274.3 EPE34490.1 - 0.088 12.4 1.6 0.18 11.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3074) UPF0160 PF03690.8 EPE34491.1 - 3.2e-127 424.3 0.0 3.6e-127 424.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Endosulfine PF04667.12 EPE34492.1 - 9.2e-21 73.6 0.0 1.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.8 EPE34493.1 - 1.2e-50 171.6 0.0 1.5e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.17 EPE34494.1 - 1.4e-111 373.6 0.0 1.9e-111 373.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase WD40 PF00400.27 EPE34495.1 - 1.7e-25 87.9 3.3 1.1e-05 25.0 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat CTP_transf_2 PF01467.21 EPE34497.1 - 1e-16 61.3 0.0 8.7e-14 51.8 0.0 2.9 2 1 0 2 2 2 2 Cytidylyltransferase Aminotran_4 PF01063.14 EPE34498.1 - 2e-23 83.1 0.0 2.9e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV ACCA PF03255.9 EPE34499.1 - 0.16 11.5 3.1 7.8 6.0 0.9 2.6 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2115 PF09888.4 EPE34499.1 - 0.38 10.8 3.0 8.3 6.4 0.6 2.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) DUF29 PF01724.11 EPE34499.1 - 0.98 9.2 5.3 2 8.2 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF29 Flavoprotein PF02441.14 EPE34500.1 - 1.8e-38 131.1 0.1 2.3e-38 130.7 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.19 EPE34501.1 - 1.2e-15 57.2 0.0 2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin APC_crr PF05923.7 EPE34501.1 - 0.076 12.6 0.0 5.9 6.6 0.0 2.5 2 0 0 2 2 2 0 APC cysteine-rich region DPBB_1 PF03330.13 EPE34503.1 - 9.3e-07 28.7 0.4 3.5e-06 26.9 0.1 2.2 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel zf-TFIIB PF13453.1 EPE34503.1 - 0.12 11.5 0.0 0.3 10.3 0.0 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Aldedh PF00171.17 EPE34504.1 - 1.6e-79 267.4 0.0 1.9e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3797 PF12677.2 EPE34504.1 - 0.0085 15.6 0.1 0.024 14.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3797) Sec6 PF06046.8 EPE34504.1 - 0.023 12.8 0.1 0.032 12.3 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec6 Oxidored_nitro PF00148.14 EPE34504.1 - 0.06 11.9 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase MRP-S28 PF10213.4 EPE34505.1 - 3.6e-43 146.6 0.1 6.2e-43 145.9 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.11 EPE34506.1 - 9.6e-17 61.1 0.0 3e-16 59.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EPE34506.1 - 0.00016 21.0 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 PRA-PH PF01503.12 EPE34508.1 - 0.2 11.9 3.5 0.81 10.0 0.5 2.5 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF883 PF05957.8 EPE34508.1 - 1.7 9.0 27.2 3.9 7.9 6.3 4.9 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) Ribosomal_L17 PF01196.14 EPE34509.1 - 1.2e-33 115.5 0.0 1.8e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 DUF1253 PF06862.7 EPE34510.1 - 1.4e-165 550.9 0.0 1.9e-165 550.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) MitMem_reg PF13012.1 EPE34511.1 - 4.3e-15 55.8 0.0 7.1e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EPE34511.1 - 5.5e-15 55.1 0.0 8.2e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SUZ PF12752.2 EPE34512.1 - 1.9e-15 57.0 4.0 1.9e-15 57.0 2.7 3.4 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 EPE34512.1 - 7.3e-09 35.2 0.0 1.7e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 R3H domain SOBP PF15279.1 EPE34513.1 - 0.52 10.6 14.7 0.64 10.3 10.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Hid1 PF12722.2 EPE34513.1 - 10 3.6 7.2 11 3.5 5.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein cwf18 PF08315.7 EPE34514.1 - 2.7e-44 150.7 4.9 2.7e-44 150.7 3.4 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor HK97-gp10_like PF04883.7 EPE34514.1 - 0.21 12.5 4.7 1.9 9.4 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component PPR_2 PF13041.1 EPE34515.1 - 9.8e-20 70.2 0.0 8.3e-10 38.4 0.0 4.3 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 EPE34515.1 - 3.2e-11 42.5 0.0 4.9e-05 23.2 0.0 4.6 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 EPE34515.1 - 1.7e-09 37.0 0.0 0.01 15.7 0.0 4.6 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 EPE34515.1 - 0.00042 19.7 0.1 0.039 13.4 0.0 3.7 4 0 0 4 4 4 1 PPR repeat IBR PF01485.16 EPE34516.1 - 9.9e-10 38.1 19.9 4.6e-07 29.6 1.4 5.0 4 1 1 5 5 5 3 IBR domain His_Phos_1 PF00300.17 EPE34517.1 - 8.4e-17 61.6 0.0 9.9e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) He_PIG PF05345.7 EPE34518.1 - 5.8e-08 32.6 31.2 0.013 15.5 1.2 6.0 6 1 1 7 7 7 4 Putative Ig domain TMEM154 PF15102.1 EPE34518.1 - 1.4e-05 24.8 0.2 3.6e-05 23.5 0.2 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 EPE34518.1 - 8.7e-05 22.0 0.0 0.00023 20.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 EPE34518.1 - 0.001 18.3 0.8 0.0031 16.7 0.5 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain BatD PF13584.1 EPE34518.1 - 0.0077 14.8 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 Oxygen tolerance Herpes_gE PF02480.11 EPE34518.1 - 0.0097 14.2 0.1 0.017 13.3 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF2207 PF09972.4 EPE34518.1 - 0.2 10.1 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PP2C PF00481.16 EPE34519.1 - 1e-83 280.6 0.1 1.9e-83 279.7 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EPE34519.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C CTP_transf_2 PF01467.21 EPE34520.1 - 3.9e-21 75.7 0.0 9.3e-21 74.5 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase Oxidored_q6 PF01058.17 EPE34521.1 - 3.1e-22 78.5 0.0 4.5e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mpp10 PF04006.7 EPE34522.1 - 6e-92 308.9 74.3 1.6e-88 297.6 18.8 2.6 1 1 1 2 2 2 2 Mpp10 protein Fe-ADH PF00465.14 EPE34523.1 - 1.2e-69 234.6 0.0 1.6e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EPE34523.1 - 8e-09 35.1 0.1 4.3e-06 26.2 0.2 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase F-box PF00646.28 EPE34525.1 - 1.3e-07 31.0 0.0 0.0029 17.1 0.0 2.6 2 1 0 2 2 2 2 F-box domain F-box-like PF12937.2 EPE34525.1 - 3.8e-07 29.7 0.1 0.0056 16.3 0.0 2.3 2 0 0 2 2 2 2 F-box-like DUF1770 PF08589.5 EPE34525.1 - 0.0027 18.2 0.7 0.0046 17.5 0.5 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Tctex-1 PF03645.8 EPE34526.1 - 1.6e-35 121.0 0.0 1.8e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 EPE34527.1 - 1.7e-12 47.3 5.0 1.4e-11 44.4 3.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.15 EPE34527.1 - 0.019 14.5 6.2 0.025 14.1 4.3 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 SdpI PF13630.1 EPE34527.1 - 4.1 7.1 5.8 8.6 6.1 1.7 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family Alba PF01918.16 EPE34528.1 - 0.0013 18.2 0.1 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 Alba Ferric_reduct PF01794.14 EPE34529.1 - 0.021 14.8 0.5 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase like transmembrane component YjgP_YjgQ PF03739.9 EPE34529.1 - 0.026 13.2 1.1 0.04 12.6 0.8 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family GpcrRhopsn4 PF10192.4 EPE34529.1 - 0.062 12.4 0.3 0.57 9.3 0.2 2.1 2 0 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain RRM_1 PF00076.17 EPE34531.1 - 2.2e-16 59.2 0.0 3.6e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE34531.1 - 1.1e-13 50.8 0.0 2.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE34531.1 - 2.5e-05 24.0 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4201 PF13870.1 EPE34531.1 - 0.0062 15.9 0.8 0.0084 15.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Packaging_FI PF14000.1 EPE34531.1 - 0.019 15.1 1.3 0.027 14.6 0.9 1.2 1 0 0 1 1 1 0 DNA packaging protein FI IncA PF04156.9 EPE34531.1 - 0.039 13.5 1.4 0.049 13.2 1.0 1.1 1 0 0 1 1 1 0 IncA protein HrpA_pilin PF09589.5 EPE34531.1 - 0.071 13.5 2.9 0.097 13.0 2.0 1.2 1 0 0 1 1 1 0 HrpA pilus formation protein DUF972 PF06156.8 EPE34531.1 - 0.15 12.4 1.0 0.21 11.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 EPE34531.1 - 0.75 9.3 4.1 1.1 8.7 2.9 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF4337 PF14235.1 EPE34531.1 - 1.6 8.5 5.5 2.1 8.1 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GRP PF07172.6 EPE34531.1 - 3.8 8.0 18.1 0.43 11.0 9.1 1.8 2 0 0 2 2 2 0 Glycine rich protein family HECT PF00632.20 EPE34532.1 - 8.3e-90 301.1 0.0 1.4e-89 300.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EPE34532.1 - 6e-32 109.1 18.1 1.2e-10 41.0 0.2 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EPE34532.1 - 3.8e-16 58.7 0.0 1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain CFEM PF05730.6 EPE34533.1 - 2.7 7.8 7.5 9.3 6.1 5.2 2.1 1 1 0 1 1 1 0 CFEM domain SPX PF03105.14 EPE34534.1 - 9.9e-19 68.1 5.6 2.5e-12 47.1 0.4 3.0 1 1 1 2 2 2 2 SPX domain DUF2985 PF11204.3 EPE34534.1 - 0.28 10.9 2.3 0.64 9.8 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) CorA PF01544.13 EPE34534.1 - 4.8 6.1 5.6 0.27 10.2 0.2 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein adh_short PF00106.20 EPE34535.1 - 2.3e-25 89.4 0.0 3.3e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE34535.1 - 5e-25 88.6 0.0 5.9e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE34535.1 - 4.2e-11 42.8 0.0 5.6e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPE34535.1 - 0.00097 18.8 0.1 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_C3 PF00548.15 EPE34535.1 - 0.02 14.6 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) OTCace PF00185.19 EPE34535.1 - 0.036 13.9 0.1 0.058 13.2 0.0 1.4 1 1 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain RNA_pol_Rpb2_6 PF00562.23 EPE34536.1 - 0.026 13.2 0.7 0.034 12.8 0.5 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Mucin PF01456.12 EPE34536.1 - 3.8 7.2 13.4 5.3 6.8 9.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein ALAD PF00490.16 EPE34538.1 - 3.4e-115 384.3 0.0 4.3e-115 384.0 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Acyl_transf_1 PF00698.16 EPE34539.1 - 4.1e-20 72.3 0.0 1.2e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain Sedlin_N PF04628.8 EPE34540.1 - 5.3e-10 39.2 0.0 6.4e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EPE34540.1 - 0.13 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Sybindin-like family AFG1_ATPase PF03969.11 EPE34541.1 - 7.6e-58 196.0 0.6 1.1e-25 90.1 0.0 5.1 4 1 1 5 5 5 5 AFG1-like ATPase AAA_5 PF07728.9 EPE34541.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPE34541.1 - 8.7e-05 22.5 1.3 0.041 13.8 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA PF00004.24 EPE34541.1 - 9.9e-05 22.5 0.0 0.0005 20.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE34541.1 - 0.004 17.3 0.0 0.021 14.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EPE34541.1 - 0.11 11.5 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Mg_chelatase PF01078.16 EPE34541.1 - 0.13 11.3 0.0 0.32 10.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EPE34541.1 - 0.15 11.5 0.0 0.53 9.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 EPE34541.1 - 0.16 12.2 0.1 26 5.1 0.0 2.6 1 1 1 2 2 2 0 ABC transporter Nucleoporin_C PF03177.9 EPE34542.1 - 1.7e-89 300.9 23.0 2.4e-89 300.4 15.9 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EPE34542.1 - 5.6e-74 249.3 0.0 7.5e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DUF2949 PF11165.3 EPE34542.1 - 0.072 13.2 0.1 0.33 11.1 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2949) Pkinase PF00069.20 EPE34544.1 - 2.8e-36 125.0 0.0 3.6e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE34544.1 - 1.8e-14 53.4 0.0 2.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPE34544.1 - 0.012 15.3 0.0 0.5 10.0 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family EMP24_GP25L PF01105.19 EPE34545.1 - 7.4e-53 178.9 0.0 8.4e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Hexapep PF00132.19 EPE34547.1 - 2.5e-12 45.7 16.3 3.7e-07 29.3 1.7 3.6 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EPE34547.1 - 6.9e-10 38.7 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EPE34547.1 - 1.6e-09 37.1 17.0 2.9e-05 23.5 3.0 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 EPE34547.1 - 3.8e-09 36.3 8.1 8e-09 35.2 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_11 PF13720.1 EPE34547.1 - 0.15 12.3 0.1 0.38 11.0 0.1 1.7 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 2-oxoacid_dh PF00198.18 EPE34548.1 - 3.8e-79 265.1 0.1 5e-79 264.8 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EPE34548.1 - 2.8e-18 65.3 0.9 5.7e-18 64.3 0.6 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF605 PF04652.11 EPE34548.1 - 0.014 14.8 11.0 0.018 14.4 7.7 1.1 1 0 0 1 1 1 0 Vta1 like Biotin_lipoyl_2 PF13533.1 EPE34548.1 - 0.016 14.8 0.3 0.53 10.0 0.1 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.1 EPE34548.1 - 0.052 13.8 0.2 0.24 11.7 0.1 1.9 1 1 0 1 1 1 0 HlyD family secretion protein MIP-T3 PF10243.4 EPE34548.1 - 0.12 10.8 20.9 0.17 10.3 14.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Herpes_DNAp_acc PF04929.7 EPE34548.1 - 9.9 5.0 11.3 15 4.3 7.8 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Complex1_LYR PF05347.10 EPE34549.1 - 2.4e-09 36.8 0.5 3.4e-09 36.3 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPE34549.1 - 6.7e-07 29.4 0.5 9e-07 29.0 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Histone PF00125.19 EPE34550.1 - 8.4e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPE34550.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPE34551.1 - 2.1e-22 79.0 0.2 3.1e-22 78.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPE34551.1 - 4.7e-05 23.3 0.6 9.8e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EPE34551.1 - 0.00021 21.5 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 EPE34551.1 - 0.0067 15.1 2.2 0.0084 14.8 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RP-C PF03428.8 EPE34551.1 - 0.01 15.2 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 EPE34551.1 - 0.03 14.8 0.6 0.041 14.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) R3H PF01424.17 EPE34552.1 - 2.9e-12 46.0 0.0 1e-11 44.3 0.0 2.0 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EPE34552.1 - 2.8e-10 39.8 0.6 6.3e-10 38.6 0.1 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EPE34552.1 - 0.00028 20.6 0.1 0.00028 20.6 0.1 3.3 3 1 0 3 3 3 1 DExH-box splicing factor binding site Chromo PF00385.19 EPE34552.1 - 0.00051 19.6 0.1 0.0014 18.2 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_C54 PF03416.14 EPE34553.1 - 8.9e-92 307.1 0.0 1.2e-91 306.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_M14 PF00246.19 EPE34553.1 - 0.036 13.6 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc carboxypeptidase DnaJ PF00226.26 EPE34554.1 - 1.5e-25 88.7 0.3 1.5e-25 88.7 0.2 2.9 3 0 0 3 3 3 1 DnaJ domain zf-C2H2_jaz PF12171.3 EPE34554.1 - 5.7e-10 39.0 5.1 1.3e-09 37.8 3.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPE34554.1 - 3.1e-09 36.7 2.7 3.1e-09 36.7 1.9 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EPE34554.1 - 6.2e-06 26.2 10.6 0.00091 19.2 3.2 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EPE34554.1 - 6.1e-05 23.1 6.1 0.055 13.8 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE34554.1 - 0.00012 22.1 2.4 0.18 12.2 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger RPT PF13446.1 EPE34554.1 - 0.0049 16.2 0.3 0.021 14.1 0.0 2.1 2 1 0 2 2 2 1 A repeated domain in UCH-protein DUF2387 PF09526.5 EPE34554.1 - 0.063 13.2 2.9 0.27 11.1 2.0 2.1 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) zf-H2C2_2 PF13465.1 EPE34554.1 - 0.11 12.8 2.9 3.5 8.1 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double domain Elf1 PF05129.8 EPE34554.1 - 0.55 9.9 6.3 4.2 7.1 0.9 2.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like LIM PF00412.17 EPE34554.1 - 0.8 9.8 4.0 3.5 7.7 0.2 2.5 2 0 0 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 EPE34554.1 - 3.4 7.6 5.0 0.68 9.9 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger SPX PF03105.14 EPE34555.1 - 4.8e-39 134.7 0.4 6e-39 134.4 0.3 1.1 1 0 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.1 EPE34555.1 - 1.1e-07 31.3 8.2 2e-07 30.5 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE34555.1 - 4.3e-07 29.4 9.7 7.7e-07 28.6 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE34555.1 - 1.4e-06 28.2 11.2 2.4e-06 27.4 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPE34555.1 - 1.6e-06 27.8 8.2 2.9e-06 27.0 5.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EPE34555.1 - 3e-05 23.6 7.5 5.6e-05 22.7 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPE34555.1 - 0.0001 22.0 10.4 0.00019 21.1 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-MIZ PF02891.15 EPE34555.1 - 0.005 16.3 8.9 0.0098 15.3 6.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EPE34555.1 - 0.015 15.0 7.4 0.015 15.0 5.2 2.4 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_4 PF14570.1 EPE34555.1 - 0.24 11.0 7.9 0.048 13.2 2.3 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain YccV-like PF08755.6 EPE34556.1 - 2.6e-25 88.2 0.1 5.2e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EPE34556.1 - 5.5e-10 38.9 0.0 1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EPE34556.1 - 1.7e-07 30.8 0.6 3.9e-07 29.6 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE34556.1 - 3e-07 29.8 0.6 6.4e-07 28.8 0.4 1.6 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 EPE34556.1 - 0.0011 19.3 0.1 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Peptidase_C12 PF01088.16 EPE34557.1 - 7.4e-58 195.2 0.0 1.9e-55 187.3 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 HELP PF03451.9 EPE34557.1 - 0.033 13.6 0.0 0.24 10.9 0.0 2.3 2 0 0 2 2 2 0 HELP motif Metallophos PF00149.23 EPE34558.1 - 1.1e-38 132.6 0.1 1.8e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EPE34558.1 - 2.5e-30 104.3 1.9 6.6e-30 102.9 1.3 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EPE34558.1 - 4.1e-18 64.7 9.6 1.1e-16 60.1 2.4 2.7 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EPE34558.1 - 5.2e-13 47.8 4.5 0.0011 18.6 0.3 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPE34558.1 - 6.2e-12 44.5 6.5 0.00033 20.1 0.2 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPE34558.1 - 5.5e-06 26.8 5.7 0.042 14.5 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPE34558.1 - 1.3e-05 24.9 0.5 0.0032 17.2 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPE34558.1 - 0.00015 22.1 2.5 0.69 10.7 0.1 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 EPE34558.1 - 0.00067 19.9 0.8 0.089 13.2 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPE34558.1 - 0.023 15.0 4.1 4 7.8 1.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPE34558.1 - 0.024 14.7 4.4 2.1 8.7 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPE34558.1 - 0.042 13.8 1.2 0.13 12.1 0.9 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPE34558.1 - 0.9 9.4 7.9 1.2 9.1 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat adh_short PF00106.20 EPE34560.1 - 5.9e-17 62.0 0.0 7.9e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE34560.1 - 5e-08 32.8 0.0 6.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE34560.1 - 2.2e-06 27.2 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EPE34560.1 - 1e-05 25.4 0.0 1.2e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPE34560.1 - 0.11 12.5 0.2 0.2 11.6 0.2 1.8 1 1 0 1 1 1 0 NADH(P)-binding OMPdecase PF00215.19 EPE34561.1 - 8.4e-72 241.2 0.0 9.6e-72 241.0 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MFS_1 PF07690.11 EPE34562.1 - 2.4e-36 125.1 57.2 1.8e-35 122.2 37.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily WBP-1 PF11669.3 EPE34562.1 - 0.012 15.6 0.1 0.25 11.4 0.0 2.3 2 0 0 2 2 2 0 WW domain-binding protein 1 Ribosomal_L1 PF00687.16 EPE34563.1 - 2.2e-51 174.2 0.5 2.7e-51 174.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.13 EPE34563.1 - 0.084 11.3 0.1 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Acyl-CoA_dh_1 PF00441.19 EPE34565.1 - 8.4e-32 110.3 1.1 1.2e-31 109.8 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPE34565.1 - 8.7e-20 69.9 0.4 1.9e-19 68.9 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EPE34565.1 - 3e-12 47.1 0.3 3e-11 43.9 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EPE34565.1 - 2e-07 31.2 0.2 3.9e-07 30.4 0.1 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Skp1 PF01466.14 EPE34567.1 - 1.4e-39 133.9 1.1 2.5e-39 133.1 0.8 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EPE34567.1 - 5.2e-21 74.5 0.4 1e-20 73.5 0.2 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EPE34567.1 - 0.016 15.1 0.5 0.016 15.1 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Arf PF00025.16 EPE34568.1 - 1.1e-66 223.3 0.0 1.4e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EPE34568.1 - 6.6e-09 35.3 0.0 8.6e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EPE34568.1 - 1e-08 34.6 0.0 1.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EPE34568.1 - 8.3e-08 31.3 0.1 1.4e-07 30.5 0.1 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 EPE34568.1 - 3.4e-06 26.3 0.0 4.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EPE34568.1 - 3.7e-06 27.4 0.0 5.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EPE34568.1 - 0.00041 19.8 0.1 0.0029 17.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPE34568.1 - 0.00086 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 EPE34568.1 - 0.011 14.4 0.0 0.02 13.6 0.0 1.5 1 1 0 1 1 1 0 ArgK protein DUF3986 PF13143.1 EPE34568.1 - 0.12 12.8 0.2 0.32 11.4 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Catalase PF00199.14 EPE34569.1 - 3.4e-186 618.5 1.5 4.2e-186 618.2 1.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EPE34569.1 - 1.1e-13 50.8 0.1 3.6e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Inhibitor_I9 PF05922.11 EPE34569.1 - 0.14 12.7 0.2 8.7 6.9 0.1 2.5 2 0 0 2 2 2 0 Peptidase inhibitor I9 14-3-3 PF00244.15 EPE34570.1 - 3.2e-11 42.7 0.2 5.1e-10 38.8 0.0 2.0 2 0 0 2 2 2 2 14-3-3 protein DUF1510 PF07423.6 EPE34571.1 - 0.51 9.6 52.0 0.015 14.7 15.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SAPS PF04499.10 EPE34571.1 - 0.83 8.2 22.6 1.6 7.2 1.5 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 EPE34571.1 - 0.84 8.0 68.4 0.77 8.1 19.2 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 EPE34571.1 - 2.2 6.2 32.5 0.11 10.5 10.8 2.1 2 0 0 2 2 2 0 CDC45-like protein MFS_1 PF07690.11 EPE34572.1 - 1.7e-39 135.5 55.7 4.5e-39 134.1 36.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE34572.1 - 4.6e-13 48.2 19.7 7.8e-13 47.4 13.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rhomboid PF01694.17 EPE34574.1 - 2.1e-09 37.5 9.5 3.4e-09 36.8 6.6 1.2 1 0 0 1 1 1 1 Rhomboid family ABC_tran PF00005.22 EPE34575.1 - 7.1e-15 55.5 0.1 1.8e-13 50.9 0.1 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPE34575.1 - 3.3e-10 40.4 1.1 0.00037 20.5 0.3 2.1 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EPE34575.1 - 3.1e-05 23.2 0.0 0.2 10.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EPE34575.1 - 6.9e-05 22.1 0.0 0.037 13.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPE34575.1 - 0.00059 19.3 0.1 0.001 18.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EPE34575.1 - 0.00063 17.2 0.2 0.00084 16.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PduV-EutP PF10662.4 EPE34575.1 - 0.0019 17.6 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EPE34575.1 - 0.016 15.5 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPE34575.1 - 0.021 15.6 0.2 0.039 14.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EPE34575.1 - 0.029 13.7 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPE34575.1 - 0.041 13.8 0.3 0.067 13.1 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPE34575.1 - 0.046 13.7 0.2 0.065 13.2 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EPE34575.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 EPE34575.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 EPE34575.1 - 0.1 11.8 0.2 0.18 11.0 0.2 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_13 PF13166.1 EPE34575.1 - 0.16 10.4 0.1 0.21 9.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPE34575.1 - 0.16 11.8 0.1 0.61 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EPE34575.1 - 0.16 11.4 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Phage_lambd_GpG PF06894.6 EPE34575.1 - 0.18 11.4 0.0 0.59 9.7 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage lambda minor tail protein (GpG) WD40 PF00400.27 EPE34576.1 - 3e-56 185.4 19.7 6.6e-09 35.3 0.1 12.3 12 0 0 12 12 12 9 WD domain, G-beta repeat FixQ PF05545.6 EPE34577.1 - 7.4 6.3 15.0 0.69 9.6 0.8 3.4 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Abhydrolase_6 PF12697.2 EPE34578.1 - 1.3e-22 80.8 0.0 1.5e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE34578.1 - 2.6e-07 30.5 0.0 3.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Urm1 PF09138.6 EPE34579.1 - 1.5e-32 111.6 0.0 1.7e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) zf-C2H2 PF00096.21 EPE34580.1 - 5.7e-18 64.0 22.3 6.2e-05 23.1 0.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPE34580.1 - 3.1e-15 55.6 28.4 1.3e-08 34.7 0.6 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPE34580.1 - 1.2e-13 50.3 19.2 0.002 18.3 0.4 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 EPE34580.1 - 0.041 13.8 10.3 0.98 9.4 0.1 4.3 4 0 0 4 4 4 0 Zinc ribbon domain zf-met PF12874.2 EPE34580.1 - 0.23 11.7 7.2 32 4.9 0.7 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 EPE34580.1 - 0.86 9.3 10.7 6.7 6.4 0.2 3.6 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.1 EPE34580.1 - 1.2 9.1 8.6 1.2 9.1 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.7 EPE34580.1 - 1.5 8.8 8.8 3.7 7.6 0.3 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2HC_2 PF13913.1 EPE34580.1 - 2.2 8.0 6.0 19 5.0 0.3 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Ribosomal_L5_C PF00673.16 EPE34582.1 - 1.2e-22 79.4 0.0 4e-22 77.7 0.0 1.9 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EPE34582.1 - 5e-06 26.1 0.0 9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 UCH_1 PF13423.1 EPE34583.1 - 2.5e-73 247.1 0.0 1e-72 245.0 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 EPE34583.1 - 1.9e-17 63.2 0.0 3.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MARVEL PF01284.18 EPE34584.1 - 4.5e-06 26.5 21.5 9e-06 25.5 14.0 1.9 1 1 1 2 2 2 1 Membrane-associating domain 7TM_transglut PF14402.1 EPE34584.1 - 0.6 8.9 5.9 0.81 8.5 4.1 1.2 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase FAD_binding_4 PF01565.18 EPE34586.1 - 1.7e-17 63.2 1.2 1.7e-17 63.2 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPE34586.1 - 0.079 12.8 0.2 0.24 11.3 0.1 1.8 2 0 0 2 2 2 0 Berberine and berberine like DUF1217 PF06748.7 EPE34586.1 - 0.17 11.9 1.8 4.3 7.3 0.3 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1217) DUF2015 PF09435.5 EPE34588.1 - 3.8e-40 136.6 0.2 4e-40 136.5 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 EPE34589.1 - 1e-31 109.7 1.4 1.5e-31 109.2 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.13 EPE34590.1 - 8.9e-44 149.2 0.0 1.3e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EPE34590.1 - 9.1e-43 145.4 0.1 1.3e-42 144.9 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EPE34590.1 - 0.053 12.2 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EPE34590.1 - 0.062 12.6 0.3 2.9 7.1 0.2 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TRAPP PF04051.11 EPE34591.1 - 1.5e-43 147.9 0.0 1.9e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.27 EPE34592.1 - 1.3e-69 227.7 14.6 1.4e-10 40.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EPE34592.1 - 6.2e-25 87.2 2.3 9.5e-25 86.6 1.6 1.3 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EPE34592.1 - 0.0012 17.1 0.2 0.042 12.1 0.1 2.5 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 EPE34592.1 - 0.0056 14.8 0.2 1.4 6.9 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPE34592.1 - 0.018 13.8 0.1 0.47 9.1 0.1 2.9 2 1 2 4 4 4 0 Nup133 N terminal like Nbas_N PF15492.1 EPE34592.1 - 0.063 12.3 0.0 14 4.6 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Peptidase_M35 PF02102.10 EPE34594.1 - 0.016 13.8 0.1 0.033 12.8 0.0 1.5 2 0 0 2 2 2 0 Deuterolysin metalloprotease (M35) family LRR_4 PF12799.2 EPE34596.1 - 0.3 10.7 4.1 2.5 7.8 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Lactamase_B PF00753.22 EPE34597.1 - 8.6e-28 97.3 0.2 1.4e-27 96.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPE34597.1 - 4.9e-08 32.7 0.0 6.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPE34597.1 - 0.0062 16.2 0.3 0.051 13.2 0.1 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain DUF1236 PF06823.7 EPE34597.1 - 0.011 15.4 0.3 0.49 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) LVIVD PF08309.6 EPE34597.1 - 0.082 11.9 0.5 0.17 10.9 0.2 1.6 2 0 0 2 2 2 0 LVIVD repeat DUF1264 PF06884.6 EPE34598.1 - 4e-77 257.4 0.1 4.8e-77 257.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) TauD PF02668.11 EPE34599.1 - 2.7e-43 148.5 0.5 3.3e-43 148.2 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Usp PF00582.21 EPE34600.1 - 1.2e-19 70.9 5.1 6.5e-19 68.5 1.0 3.0 2 1 0 2 2 2 1 Universal stress protein family Ribosomal_S7 PF00177.16 EPE34601.1 - 3.8e-24 84.9 0.0 6.7e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DND1_DSRM PF14709.1 EPE34602.1 - 0.0025 18.0 0.1 0.0073 16.5 0.1 1.7 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 EPE34602.1 - 0.014 15.9 0.1 0.025 15.1 0.0 1.5 1 1 0 1 1 1 0 Double-stranded RNA binding motif NMO PF03060.10 EPE34603.1 - 2.6e-67 227.3 0.1 3.2e-67 227.0 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EPE34603.1 - 1.1e-11 44.2 0.0 3.4e-05 22.9 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EPE34603.1 - 0.0073 15.1 0.1 0.013 14.3 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EPE34603.1 - 0.017 14.4 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Glu_synthase PF01645.12 EPE34603.1 - 0.027 13.4 0.2 0.062 12.2 0.1 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase Aldo_ket_red PF00248.16 EPE34604.1 - 1.1e-50 172.1 0.0 1.3e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.17 EPE34605.1 - 3.7e-82 269.9 4.4 1.4e-22 79.1 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE34605.1 - 6.9e-56 186.1 0.3 5e-16 58.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE34605.1 - 4.2e-38 128.9 0.2 5.8e-08 32.4 0.0 5.7 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EPE34605.1 - 5.6e-30 102.8 0.9 2.1e-29 100.9 0.6 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EPE34605.1 - 1.2e-05 24.9 0.7 0.66 9.7 0.0 3.7 2 1 1 3 3 3 3 Limkain b1 CbiG_mid PF11761.3 EPE34605.1 - 0.00068 19.8 0.0 3.4 7.9 0.0 3.9 3 0 0 3 3 3 1 Cobalamin biosynthesis central region OB_RNB PF08206.6 EPE34605.1 - 0.23 10.9 2.5 14 5.2 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain DEAD PF00270.24 EPE34606.1 - 2.3e-45 154.1 0.0 1.3e-43 148.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE34606.1 - 3.2e-28 97.4 0.0 7.2e-28 96.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE34606.1 - 4.5e-05 23.3 0.0 0.00021 21.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EPE34606.1 - 0.0062 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 EPE34606.1 - 0.031 12.6 0.0 1.7 6.9 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) His_Phos_2 PF00328.17 EPE34607.1 - 4.5e-24 85.4 0.0 5.3e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PUF PF00806.14 EPE34608.1 - 1.7e-59 194.0 15.2 1.5e-08 33.6 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SapB_2 PF03489.12 EPE34608.1 - 0.19 11.7 0.6 18 5.5 0.0 3.3 2 0 0 2 2 2 0 Saposin-like type B, region 2 CPL PF08144.6 EPE34608.1 - 0.53 10.1 4.7 2.9 7.7 0.4 3.5 2 1 1 4 4 4 0 CPL (NUC119) domain DUF2299 PF10061.4 EPE34608.1 - 0.59 9.5 2.9 2.9 7.3 0.0 3.0 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2299) Herpes_gE PF02480.11 EPE34609.1 - 0.0026 16.0 0.0 0.0031 15.8 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Actin PF00022.14 EPE34610.1 - 6.2e-159 528.6 0.0 7.1e-159 528.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EPE34610.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Abhydrolase_6 PF12697.2 EPE34612.1 - 1.5e-37 129.6 0.2 1.8e-37 129.4 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE34612.1 - 2.5e-20 72.7 0.0 5.2e-20 71.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE34612.1 - 4.7e-15 55.7 0.0 4.2e-11 42.8 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.15 EPE34612.1 - 8.8e-07 29.3 0.0 1.1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.9 EPE34612.1 - 1.2e-06 27.2 0.0 2.4e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Ndr family PGAP1 PF07819.8 EPE34612.1 - 2.1e-06 27.4 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EPE34612.1 - 5.1e-06 26.2 0.0 6.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EPE34612.1 - 0.0044 16.8 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ser_hydrolase PF06821.8 EPE34612.1 - 0.0082 15.7 0.0 0.028 14.0 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase Chlorophyllase2 PF12740.2 EPE34612.1 - 0.0083 15.0 0.0 0.018 13.9 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 EPE34612.1 - 0.019 14.5 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_4 PF08386.5 EPE34612.1 - 0.022 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein UPF0227 PF05728.7 EPE34612.1 - 0.05 13.3 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF900 PF05990.7 EPE34612.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 EPE34612.1 - 0.19 10.6 0.0 0.28 10.1 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 EPE34612.1 - 0.2 10.7 0.0 0.31 10.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) RF-1 PF00472.15 EPE34613.1 - 3.3e-24 84.8 1.1 4.8e-24 84.3 0.7 1.2 1 0 0 1 1 1 1 RF-1 domain DUF3317 PF11779.3 EPE34614.1 - 3.5e-24 84.0 6.0 4.7e-24 83.5 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) QueT PF06177.6 EPE34614.1 - 0.057 13.4 0.7 0.06 13.3 0.5 1.2 1 0 0 1 1 1 0 QueT transporter Peptidase_U4 PF03419.8 EPE34614.1 - 0.68 8.9 5.5 0.95 8.4 3.8 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA CENP-I PF07778.6 EPE34615.1 - 1.3e-80 271.0 0.9 4.4e-49 167.0 0.0 2.2 1 1 1 2 2 2 2 Mis6 GPP34 PF05719.6 EPE34615.1 - 0.068 13.2 0.3 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) Rep_fac_C PF08542.6 EPE34615.1 - 0.17 11.9 0.5 17 5.4 0.0 2.9 2 1 0 3 3 3 0 Replication factor C C-terminal domain ComK PF06338.6 EPE34616.1 - 0.09 12.1 0.1 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 ComK protein Acetyltransf_1 PF00583.19 EPE34617.1 - 5.3e-06 26.3 0.0 0.092 12.7 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE34617.1 - 0.01 15.9 0.0 0.88 9.7 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPE34617.1 - 0.13 12.4 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain APH PF01636.18 EPE34618.1 - 2.1e-11 44.0 0.0 6e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE34618.1 - 0.00025 20.6 0.3 0.00065 19.3 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPE34618.1 - 0.018 14.2 0.0 0.044 12.9 0.0 1.6 1 0 0 1 1 1 0 Ecdysteroid kinase Patatin PF01734.17 EPE34619.1 - 6.7e-13 49.0 0.2 8.7e-12 45.3 0.1 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Baculo_p74 PF04583.7 EPE34620.1 - 0.095 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae p74 conserved region LRR_4 PF12799.2 EPE34620.1 - 0.39 10.4 12.2 1.5 8.5 0.1 5.3 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) Rad9 PF04139.8 EPE34621.1 - 3.7e-44 150.7 0.1 4.7e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 Rad9 RCC1 PF00415.13 EPE34622.1 - 1.4e-32 111.6 19.7 5.5e-09 36.0 0.1 7.1 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPE34622.1 - 5e-17 61.0 27.8 1.9e-06 27.3 0.7 6.5 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat IRS PF02174.12 EPE34622.1 - 0.14 11.7 0.1 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Ribosomal_L30_N PF08079.7 EPE34623.1 - 4.9e-25 87.3 19.2 4.9e-25 87.3 13.3 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EPE34623.1 - 4.3e-18 64.6 2.4 5.3e-18 64.3 0.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Rrp15p PF07890.7 EPE34623.1 - 1.3 9.0 12.3 2.2 8.3 8.6 1.2 1 0 0 1 1 1 0 Rrp15p Fe-S_biosyn PF01521.15 EPE34624.1 - 9.2e-15 54.5 0.0 4.2e-07 29.8 0.1 2.2 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis adh_short PF00106.20 EPE34625.1 - 0.004 17.0 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase ATP-grasp_4 PF13535.1 EPE34626.1 - 9.8e-18 64.5 0.0 1.9e-16 60.3 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EPE34626.1 - 2.4e-08 33.5 0.0 5.4e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EPE34626.1 - 4e-08 32.3 0.0 2.4e-05 23.2 0.0 3.0 2 1 1 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EPE34626.1 - 0.0014 17.9 0.0 0.007 15.6 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 EPE34626.1 - 0.005 16.4 0.0 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 EPE34626.1 - 0.0062 16.4 0.0 0.021 14.6 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 EPE34626.1 - 0.02 14.3 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.1 EPE34626.1 - 0.053 12.6 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF4598 PF15370.1 EPE34627.1 - 5.1e-10 39.6 0.7 5.1e-10 39.6 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) IF4E PF01652.13 EPE34628.1 - 3.4e-38 130.7 0.2 4.1e-38 130.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Flagellin_N PF00669.15 EPE34628.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region FA_hydroxylase PF04116.8 EPE34630.1 - 2.1e-14 53.8 15.2 2.1e-14 53.8 10.5 2.4 2 1 0 2 2 2 2 Fatty acid hydroxylase superfamily Kinesin PF00225.18 EPE34632.1 - 2.8e-113 378.0 0.0 4e-113 377.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF87 PF01935.12 EPE34632.1 - 0.065 13.0 7.1 0.67 9.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF2018 PF09442.5 EPE34632.1 - 0.2 12.2 3.5 0.36 11.4 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) CCDC-167 PF15188.1 EPE34632.1 - 8.7 6.3 13.0 1.5 8.7 4.7 3.0 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 GDA1_CD39 PF01150.12 EPE34636.1 - 1.3e-98 330.3 0.0 1.7e-98 330.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PUL PF08324.6 EPE34637.1 - 7.7e-36 123.2 0.0 1.2e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 EPE34637.1 - 5.2e-34 117.1 0.0 8.8e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 EPE34637.1 - 4.3e-13 48.8 0.0 8.9e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EPE34637.1 - 0.00044 20.4 0.1 0.0033 17.6 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EPE34637.1 - 0.0027 17.4 0.0 0.0071 16.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 EPE34637.1 - 0.0054 16.2 0.0 0.0099 15.3 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.16 EPE34637.1 - 0.038 13.6 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_8 PF13905.1 EPE34637.1 - 0.087 12.9 0.0 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like DUF2847 PF11009.3 EPE34637.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) AAA_3 PF07726.6 EPE34638.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Vps16_N PF04841.8 EPE34639.1 - 2e-98 329.6 0.0 2.7e-98 329.2 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EPE34639.1 - 2.4e-82 276.4 0.0 4.2e-82 275.6 0.0 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region SET PF00856.23 EPE34639.1 - 4.8e-12 46.4 0.0 1.8e-11 44.5 0.0 2.0 1 1 0 1 1 1 1 SET domain AD PF09793.4 EPE34639.1 - 0.0063 16.3 0.0 4.5 7.1 0.0 2.6 2 0 0 2 2 2 2 Anticodon-binding domain Sed5p PF11416.3 EPE34639.1 - 0.066 12.6 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Integral membrane protein Sed5p TauD PF02668.11 EPE34640.1 - 5.7e-44 150.7 0.0 8.3e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.4 EPE34640.1 - 0.052 13.3 0.6 0.29 10.9 0.1 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain CTNNBL PF08216.6 EPE34641.1 - 5.6e-36 122.4 0.6 2.5e-35 120.3 0.1 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear GP46 PF07409.7 EPE34641.1 - 0.0074 15.5 0.7 0.015 14.6 0.1 1.8 2 0 0 2 2 2 1 Phage protein GP46 Mo25 PF08569.6 EPE34641.1 - 0.01 14.8 0.6 0.037 13.0 0.4 1.9 1 1 1 2 2 2 0 Mo25-like DUF4020 PF13212.1 EPE34641.1 - 0.054 13.0 1.0 0.14 11.6 0.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4020) Arm PF00514.18 EPE34641.1 - 0.057 13.2 0.0 0.81 9.6 0.0 2.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat MFS_1 PF07690.11 EPE34642.1 - 9.3e-45 152.8 45.0 4.1e-41 140.8 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE34642.1 - 7e-07 27.9 29.7 4.7e-06 25.2 6.0 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein DUF1500 PF07389.7 EPE34642.1 - 0.0051 16.8 0.7 0.079 12.9 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1500) Mem_trans PF03547.13 EPE34642.1 - 0.0082 14.4 3.0 0.029 12.6 0.0 2.6 1 1 1 2 2 2 1 Membrane transport protein OATP PF03137.15 EPE34642.1 - 0.045 11.7 0.1 5.2 4.9 0.0 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family F-box PF00646.28 EPE34643.1 - 9.6e-08 31.4 0.1 3.4e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EPE34643.1 - 5.2e-06 26.0 0.0 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like Cytochrome-c551 PF10643.4 EPE34643.1 - 0.071 12.4 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 adh_short PF00106.20 EPE34646.1 - 1.2e-21 77.3 0.0 1.5e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE34646.1 - 4.1e-07 29.8 0.0 5.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPE34646.1 - 3.9e-06 26.9 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE34646.1 - 2.3e-05 23.9 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EPE34646.1 - 6.7e-05 22.7 0.0 9.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EPE34646.1 - 0.094 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Fungal_trans PF04082.13 EPE34647.1 - 1.9e-12 46.6 1.1 2.7e-12 46.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE34647.1 - 1.6e-07 31.1 10.8 1.6e-07 31.1 7.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EPE34648.1 - 4.8e-107 358.3 22.1 5.7e-107 358.1 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE34648.1 - 7.7e-28 97.2 32.9 3.1e-27 95.2 16.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NDUF_B7 PF05676.8 EPE34650.1 - 6.2e-30 102.4 2.2 7.4e-30 102.1 1.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EPE34650.1 - 0.063 13.0 1.6 0.091 12.5 1.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Asp_Glu_race PF01177.17 EPE34651.1 - 3.5e-23 82.6 0.0 4.1e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Actin PF00022.14 EPE34652.1 - 2.1e-117 391.8 0.0 2.6e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPE34652.1 - 0.031 12.8 0.0 0.21 10.1 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein HAD_2 PF13419.1 EPE34653.1 - 2.6e-13 50.5 0.2 5.7e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE34653.1 - 6.8e-05 22.5 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like UQ_con PF00179.21 EPE34654.1 - 2.2e-36 124.3 0.0 2.7e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPE34654.1 - 0.023 14.4 0.0 0.074 12.7 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B Nop14 PF04147.7 EPE34654.1 - 2.9 5.7 10.0 3.6 5.4 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family UBA_4 PF14555.1 EPE34655.1 - 0.0035 16.8 0.0 0.0089 15.5 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.11 EPE34655.1 - 0.063 12.7 0.0 0.22 11.0 0.0 2.0 1 0 0 1 1 1 0 CUE domain NAD_kinase PF01513.16 EPE34656.1 - 1.8e-68 230.4 0.0 3e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase AhpC-TSA_2 PF13911.1 EPE34659.1 - 1.5e-15 57.1 0.1 5.5e-15 55.2 0.0 1.9 3 0 0 3 3 3 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EPE34659.1 - 0.00025 20.7 0.0 0.00086 18.9 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family BAR PF03114.13 EPE34660.1 - 2.6e-65 220.1 5.7 3.4e-65 219.7 4.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EPE34660.1 - 8.2e-14 50.7 0.1 1.4e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPE34660.1 - 4e-13 48.7 0.1 6.7e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPE34660.1 - 9.6e-10 37.8 0.0 2.2e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EPE34660.1 - 0.0042 16.3 8.2 0.3 10.3 2.9 2.2 2 0 0 2 2 2 2 Vps5 C terminal like MLANA PF14991.1 EPE34660.1 - 0.57 10.2 3.1 0.39 10.7 0.4 2.0 2 0 0 2 2 2 0 Protein melan-A TMPIT PF07851.8 EPE34660.1 - 5.6 5.9 7.5 1.3 7.9 0.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein Aminotran_5 PF00266.14 EPE34661.1 - 5.7e-94 314.8 0.0 7e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EPE34661.1 - 2.4e-07 30.0 0.0 3.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPE34661.1 - 2.8e-07 29.9 0.0 4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EPE34661.1 - 0.00033 19.8 0.1 0.00052 19.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EPE34661.1 - 0.01 14.1 0.2 0.023 13.0 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme zf-RING_2 PF13639.1 EPE34662.1 - 1.3e-08 34.5 7.7 2.9e-08 33.3 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPE34662.1 - 0.0014 18.6 4.1 0.0032 17.5 2.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPE34662.1 - 0.0068 16.4 9.4 0.013 15.5 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EPE34662.1 - 0.022 14.2 2.5 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_3 PF13920.1 EPE34662.1 - 0.059 13.0 9.2 0.18 11.4 6.5 1.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cellulase-like PF12876.2 EPE34662.1 - 0.074 13.4 0.0 0.81 10.1 0.0 2.3 2 0 0 2 2 2 0 Sugar-binding cellulase-like zf-RING_5 PF14634.1 EPE34662.1 - 0.11 12.2 7.5 0.2 11.4 5.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 EPE34662.1 - 0.32 10.9 9.6 0.68 9.9 4.9 2.5 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EPE34662.1 - 0.52 9.9 7.2 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Fungal_trans PF04082.13 EPE34663.1 - 6.4e-19 67.8 0.1 9.4e-19 67.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPE34663.1 - 1.1e-08 34.9 12.6 0.00067 19.8 2.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPE34663.1 - 1.3e-06 28.4 6.4 1.3e-06 28.4 4.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPE34663.1 - 0.0037 17.4 19.5 0.06 13.6 1.9 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EPE34663.1 - 0.063 13.4 1.2 0.2 11.9 0.8 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPE34663.1 - 0.18 12.0 3.6 0.78 9.9 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EPE34663.1 - 0.93 9.4 7.2 0.66 9.9 0.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger FAP PF07174.6 EPE34664.1 - 5.7 6.1 39.5 0.35 10.1 5.6 3.2 3 0 0 3 3 3 0 Fibronectin-attachment protein (FAP) Ank_2 PF12796.2 EPE34665.1 - 2.1e-15 56.7 0.0 5.3e-08 33.0 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPE34665.1 - 2.6e-12 46.5 0.9 1.7e-07 31.2 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE34665.1 - 1.6e-10 41.2 0.0 1.7e-06 28.3 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EPE34665.1 - 5.8e-08 32.1 0.2 0.00055 19.6 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EPE34665.1 - 4.3e-07 29.5 0.0 0.0018 18.3 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeat AAA_22 PF13401.1 EPE34665.1 - 0.015 15.4 0.0 0.045 13.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EPE34665.1 - 0.1 12.5 0.3 0.23 11.4 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EPE34665.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF676 PF05057.9 EPE34666.1 - 6.3e-05 22.3 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPE34666.1 - 0.0045 16.9 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPE34666.1 - 0.07 12.6 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein Peptidase_M16_C PF05193.16 EPE34667.1 - 1.2e-51 175.0 0.0 6.2e-50 169.4 0.0 2.5 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPE34667.1 - 4.3e-44 149.8 0.0 9.7e-43 145.4 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Disulph_isomer PF06491.6 EPE34667.1 - 0.018 14.8 0.2 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 Disulphide isomerase FHA PF00498.21 EPE34668.1 - 1.9e-15 56.6 0.0 3.7e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EPE34668.1 - 1.8e-06 27.6 10.1 2.9e-06 27.0 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPE34668.1 - 0.015 15.4 4.2 0.027 14.5 2.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPE34668.1 - 0.015 14.9 9.0 0.025 14.2 6.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EPE34668.1 - 0.13 11.9 5.6 0.26 11.0 3.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 EPE34668.1 - 0.21 11.3 6.2 0.6 9.8 4.4 1.7 1 1 0 1 1 1 0 zinc-RING finger domain adh_short PF00106.20 EPE34671.1 - 8.8e-21 74.5 0.1 1.2e-20 74.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE34671.1 - 3.4e-07 30.0 0.1 5.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE34671.1 - 3e-06 27.1 0.0 6.1e-06 26.1 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase CW_binding_2 PF04122.7 EPE34671.1 - 0.025 14.7 0.1 0.07 13.3 0.0 1.7 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 CRAL_TRIO PF00650.15 EPE34672.1 - 3.5e-38 130.5 0.0 4.8e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPE34672.1 - 5.9e-10 39.1 0.1 1.8e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPE34672.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain HTH_8 PF02954.14 EPE34672.1 - 0.061 12.8 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family TRAPP PF04051.11 EPE34673.1 - 1.9e-36 124.9 0.0 2.3e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_S14 PF00253.16 EPE34674.1 - 1.5e-18 65.8 3.5 1.6e-18 65.7 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EPE34674.1 - 0.015 15.0 0.5 0.019 14.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF2318 PF10080.4 EPE34674.1 - 0.083 12.6 0.1 0.089 12.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Prim_Zn_Ribbon PF08273.7 EPE34674.1 - 0.34 11.0 3.4 7.2 6.7 0.2 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase DUF3638 PF12340.3 EPE34675.1 - 1.2e-100 335.1 0.6 4.2e-100 333.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EPE34675.1 - 1.8e-15 55.7 0.0 4.4e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) AA_permease PF00324.16 EPE34676.1 - 1.9e-139 465.0 39.8 2.4e-139 464.7 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE34676.1 - 1.7e-42 145.4 44.9 2.3e-42 145.0 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease Oxidored_molyb PF00174.14 EPE34677.1 - 4e-50 169.5 0.0 6.2e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EPE34677.1 - 1.2e-26 92.9 1.5 6.7e-26 90.4 1.0 2.1 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 EPE34677.1 - 2e-11 43.4 0.0 3.4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_2 PF03446.10 EPE34678.1 - 0.13 12.0 2.4 0.18 11.6 1.5 1.3 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TAF8_C PF10406.4 EPE34678.1 - 5.3 7.1 5.7 3.1 7.9 0.3 2.5 2 1 1 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term MIS13 PF08202.6 EPE34679.1 - 1.1e-51 175.7 4.5 1.1e-51 175.7 3.2 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family CDRT4 PF15213.1 EPE34679.1 - 0.041 13.9 0.8 0.041 13.9 0.6 2.0 2 1 0 2 2 2 0 CMT1A duplicated region transcript 4 protein Methyltransf_16 PF10294.4 EPE34681.1 - 1.5e-21 76.6 0.0 2.8e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Met_10 PF02475.11 EPE34681.1 - 4.8e-05 23.0 0.0 7.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EPE34681.1 - 6e-05 23.5 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE34681.1 - 9.1e-05 21.8 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EPE34681.1 - 0.0015 19.0 0.0 0.0093 16.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE34681.1 - 0.0061 16.2 0.0 0.031 14.0 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EPE34681.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EPE34681.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EPE34681.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EPE34681.1 - 0.12 12.0 0.1 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EPE34681.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ribosomal_S24e PF01282.14 EPE34682.1 - 3.3e-34 116.5 0.0 5.5e-34 115.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.1 EPE34682.1 - 0.024 14.0 1.5 0.029 13.7 1.1 1.2 1 0 0 1 1 1 0 RRXRR protein Pro_isomerase PF00160.16 EPE34684.1 - 1.9e-37 128.8 0.0 3.1e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EPE34684.1 - 4.7e-15 54.9 0.0 8e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE34684.1 - 2.6e-10 40.1 0.0 7.2e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE34684.1 - 1.5e-07 31.1 0.0 3.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 EPE34685.1 - 2.1e-08 33.8 5.0 3.6e-08 33.1 3.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LZ_Tnp_IS66 PF13007.2 EPE34685.1 - 0.037 14.6 1.8 1.6 9.4 0.1 2.5 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain Peptidase_S41 PF03572.13 EPE34687.1 - 1.6e-05 24.3 0.0 4.7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 DUF4003 PF13170.1 EPE34687.1 - 0.085 12.0 0.3 0.15 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Bromodomain PF00439.20 EPE34687.1 - 0.097 12.6 0.0 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 Bromodomain HET PF06985.6 EPE34688.1 - 5.8e-31 107.5 0.1 5.8e-31 107.5 0.1 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Atu4866 PF11512.3 EPE34689.1 - 0.0099 15.5 0.7 0.014 15.1 0.5 1.3 1 0 0 1 1 1 1 Agrobacterium tumefaciens protein Atu4866 DLH PF01738.13 EPE34693.1 - 3.1e-21 75.6 0.0 2.9e-20 72.4 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPE34693.1 - 6.8e-09 35.6 0.0 9.9e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE34693.1 - 7.4e-07 29.2 0.1 0.006 16.4 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EPE34693.1 - 0.027 14.0 0.0 0.73 9.3 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 EPE34693.1 - 0.063 11.5 0.0 0.089 11.0 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II RRP7 PF12923.2 EPE34694.1 - 2.5e-33 114.8 12.3 4.4e-33 114.0 8.5 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_6 PF14259.1 EPE34694.1 - 0.00074 19.4 0.0 0.51 10.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) peroxidase PF00141.18 EPE34695.1 - 8.7e-32 110.4 0.0 1.6e-31 109.5 0.0 1.4 1 1 0 1 1 1 1 Peroxidase Trypan_PARP PF05887.6 EPE34696.1 - 0.029 14.1 20.5 0.053 13.3 13.8 1.8 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HET PF06985.6 EPE34697.1 - 3.4e-22 79.0 8.5 6.7e-21 74.9 5.9 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.1 EPE34697.1 - 3.4e-08 33.6 0.0 8.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EPE34697.1 - 5.5e-07 29.3 0.0 1.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EPE34697.1 - 0.00044 19.1 0.0 0.0009 18.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.15 EPE34697.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.1 EPE34697.1 - 0.017 15.2 0.0 0.08 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EPE34697.1 - 0.028 15.2 0.4 0.2 12.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EPE34697.1 - 0.029 13.3 0.8 0.068 12.1 0.6 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA PF00004.24 EPE34697.1 - 0.058 13.5 0.1 0.23 11.6 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EPE34697.1 - 0.087 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EPE34697.1 - 0.25 10.8 0.0 0.5 9.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad51 PF08423.6 EPE34699.1 - 2.4e-122 406.7 0.1 3.5e-122 406.2 0.1 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EPE34699.1 - 1.7e-11 43.7 0.1 2.1e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EPE34699.1 - 2.7e-11 43.4 3.1 2.4e-10 40.4 0.4 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix domain AAA_25 PF13481.1 EPE34699.1 - 5.6e-11 42.1 0.0 8.1e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EPE34699.1 - 7.5e-10 38.3 0.0 1.5e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 KaiC RNA_pol_A_CTD PF03118.10 EPE34699.1 - 2.3e-05 23.7 0.4 4.2e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain AAA PF00004.24 EPE34699.1 - 0.017 15.3 1.5 0.81 9.8 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE34699.1 - 0.076 13.1 0.1 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain zf-CCHC PF00098.18 EPE34700.1 - 3.4e-43 143.5 56.9 9.2e-08 31.6 1.3 7.4 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EPE34700.1 - 9.3e-08 31.6 41.7 0.098 12.3 0.7 7.2 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EPE34700.1 - 0.001 18.7 41.2 0.52 10.0 0.5 7.0 4 2 2 6 6 6 5 Zinc knuckle ABC2_membrane_4 PF12730.2 EPE34701.1 - 0.0054 15.9 0.4 0.0072 15.5 0.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Form_Nir_trans PF01226.12 EPE34701.1 - 0.0071 15.2 0.0 0.0097 14.8 0.0 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter TetR_C_6 PF13977.1 EPE34701.1 - 0.058 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor WD40 PF00400.27 EPE34702.1 - 2e-54 179.5 8.1 7.9e-11 41.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EPE34702.1 - 0.00017 20.4 0.6 0.066 11.9 0.1 2.3 1 1 1 2 2 2 2 Nup133 N terminal like TRAPP PF04051.11 EPE34703.1 - 2.9e-37 127.5 0.1 3.5e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component LisH PF08513.6 EPE34704.1 - 0.05 13.3 0.5 0.083 12.6 0.4 1.3 1 0 0 1 1 1 0 LisH Ninjurin PF04923.7 EPE34707.1 - 0.71 9.6 8.6 0.43 10.3 0.3 3.1 3 0 0 3 3 3 0 Ninjurin zf-C2H2 PF00096.21 EPE34708.1 - 6.5e-08 32.4 7.6 0.068 13.5 0.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE34708.1 - 0.012 15.8 3.4 1.4 9.4 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPE34708.1 - 0.026 14.6 2.1 21 5.4 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EPE34708.1 - 0.18 11.9 3.9 13 5.9 0.1 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Elf1 PF05129.8 EPE34709.1 - 8 6.2 8.3 9.7 5.9 1.9 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DSBA PF01323.15 EPE34710.1 - 3.8e-19 69.0 0.0 2.3e-18 66.4 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain GRAS PF03514.9 EPE34710.1 - 0.16 10.6 0.0 0.33 9.6 0.0 1.4 2 0 0 2 2 2 0 GRAS domain family ADIP PF11559.3 EPE34712.1 - 4e-39 133.9 7.3 1e-38 132.6 5.1 1.7 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Fungal_trans_2 PF11951.3 EPE34712.1 - 0.00075 18.2 0.3 0.00075 18.2 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Retrotrans_gag PF03732.12 EPE34712.1 - 0.051 13.6 1.6 0.085 12.9 0.5 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein RTA1 PF04479.8 EPE34713.1 - 3.6e-52 177.1 15.9 3.6e-52 177.1 11.0 1.9 1 1 1 2 2 2 1 RTA1 like protein G0-G1_switch_2 PF15103.1 EPE34713.1 - 0.003 17.7 0.6 0.4 10.9 0.0 3.1 3 0 0 3 3 3 1 G0/G1 switch protein 2 Peptidase_M50 PF02163.17 EPE34713.1 - 0.24 10.3 4.1 0.5 9.3 2.6 1.8 1 1 0 1 1 1 0 Peptidase family M50 EphA2_TM PF14575.1 EPE34713.1 - 0.3 11.5 3.3 1.6 9.1 0.2 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain HET PF06985.6 EPE34714.1 - 9.9e-28 97.0 1.0 2.1e-27 95.9 0.7 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PGAP1 PF07819.8 EPE34715.1 - 1.4e-06 28.0 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EPE34715.1 - 2e-06 27.2 0.0 3.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPE34715.1 - 2.3e-05 24.3 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE34715.1 - 0.00054 19.7 0.0 0.0013 18.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EPE34715.1 - 0.0016 17.4 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 EPE34715.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 EPE34715.1 - 0.06 12.8 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold V-ATPase_G PF03179.10 EPE34716.1 - 2.6e-28 98.3 14.4 3e-28 98.1 10.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Striatin PF08232.7 EPE34716.1 - 0.004 17.4 6.4 0.005 17.1 4.4 1.0 1 0 0 1 1 1 1 Striatin family DUF87 PF01935.12 EPE34716.1 - 0.046 13.5 2.3 0.053 13.3 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 SAPS PF04499.10 EPE34716.1 - 0.18 10.4 7.3 0.19 10.3 5.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2031 PF09592.5 EPE34716.1 - 0.18 10.8 4.9 0.25 10.4 3.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2031) Vfa1 PF08432.5 EPE34716.1 - 0.21 11.6 11.3 0.23 11.4 7.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.11 EPE34716.1 - 0.29 10.6 13.4 0.32 10.4 9.3 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 OmpH PF03938.9 EPE34716.1 - 0.29 11.0 9.6 0.37 10.7 6.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF16 PF01519.11 EPE34716.1 - 1 9.5 10.0 1.4 9.1 6.9 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 ATP-synt_B PF00430.13 EPE34716.1 - 1.1 9.0 15.0 0.87 9.3 3.9 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Borrelia_P83 PF05262.6 EPE34716.1 - 1.2 7.3 13.1 1.2 7.2 9.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein FAM91_C PF14648.1 EPE34716.1 - 1.2 7.9 3.1 1.4 7.6 2.2 1.0 1 0 0 1 1 1 0 FAM91 C-terminus NPR3 PF03666.8 EPE34716.1 - 1.7 7.0 5.6 1.9 6.9 3.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TRAP_alpha PF03896.11 EPE34716.1 - 2.5 7.0 7.3 2.9 6.7 5.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Arc_PepC_II PF06847.6 EPE34716.1 - 3.2 8.2 7.2 24 5.4 5.0 2.0 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II OmpH PF03938.9 EPE34717.1 - 0.059 13.3 1.6 0.065 13.1 1.1 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2870 PF11069.3 EPE34717.1 - 0.068 13.2 0.1 0.074 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Histidinol_dh PF00815.15 EPE34717.1 - 0.069 11.7 0.9 0.083 11.5 0.6 1.0 1 0 0 1 1 1 0 Histidinol dehydrogenase RNA_pol_Rpb2_6 PF00562.23 EPE34718.1 - 4.6e-125 417.3 0.1 5.2e-124 413.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPE34718.1 - 2.6e-64 215.9 0.0 4.5e-64 215.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EPE34718.1 - 3.1e-46 157.2 0.0 5e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EPE34718.1 - 1.5e-29 102.0 0.0 3.9e-29 100.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EPE34718.1 - 2.5e-24 84.8 0.7 7e-24 83.4 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EPE34718.1 - 4.2e-23 80.8 0.0 9.9e-23 79.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EPE34718.1 - 1.5e-21 76.1 0.1 3.3e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ADH_N PF08240.7 EPE34719.1 - 8.2e-26 89.9 7.5 1.4e-25 89.1 5.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE34719.1 - 1.1e-18 67.0 0.0 1.8e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE34719.1 - 1.5e-06 29.1 0.0 2.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPE34719.1 - 0.0013 17.9 0.1 0.0022 17.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EPE34719.1 - 0.008 16.2 0.0 0.018 15.1 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF4241 PF14025.1 EPE34719.1 - 0.1 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Pex24p PF06398.6 EPE34721.1 - 2.8e-94 315.8 1.0 4.1e-94 315.3 0.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 EPE34721.1 - 0.4 8.4 4.2 0.24 9.2 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) Pkinase PF00069.20 EPE34722.1 - 6.8e-56 189.2 0.0 1.2e-55 188.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE34722.1 - 7.3e-21 74.3 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EPE34722.1 - 0.027 14.0 0.8 0.08 12.5 0.4 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 EPE34722.1 - 0.053 13.2 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family COesterase PF00135.23 EPE34723.1 - 1e-78 265.4 1.2 2.1e-78 264.3 0.9 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE34723.1 - 5.7e-10 39.1 0.0 1.9e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold YqzH PF14164.1 EPE34725.1 - 0.67 9.9 4.6 1.4 8.8 3.2 1.5 1 0 0 1 1 1 0 YqzH-like protein Sugar_tr PF00083.19 EPE34726.1 - 2.3e-84 283.5 25.0 3.2e-84 283.1 17.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE34726.1 - 2e-11 43.2 41.1 2.6e-09 36.2 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DHHA1 PF02272.14 EPE34727.1 - 0.0039 16.8 0.0 31 4.3 0.0 4.3 5 0 0 5 5 5 0 DHHA1 domain zf-AN1 PF01428.11 EPE34727.1 - 0.14 12.0 15.7 45 4.0 0.0 6.8 7 0 0 7 7 7 0 AN1-like Zinc finger DUF4145 PF13643.1 EPE34727.1 - 0.26 11.1 1.8 6.3 6.7 0.2 3.4 2 1 1 4 4 4 0 Domain of unknown function (DUF4145) DUF2256 PF10013.4 EPE34727.1 - 1.1 9.0 30.8 16 5.3 0.1 7.2 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.9 EPE34727.1 - 1.2 8.8 19.9 63 3.3 0.0 7.0 7 0 0 7 7 7 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.5 EPE34727.1 - 3.3 7.7 19.7 20 5.2 0.1 6.8 7 0 0 7 7 7 0 Zinc ribbon domain Auto_anti-p27 PF06677.7 EPE34727.1 - 4.7 7.0 27.3 23 4.8 0.0 7.1 7 0 0 7 7 7 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) BTK PF00779.14 EPE34727.1 - 8.4 6.1 20.4 23 4.6 0.1 5.7 5 0 0 5 5 5 0 BTK motif Sugar_tr PF00083.19 EPE34728.1 - 4.2e-67 226.6 23.7 4.8e-67 226.4 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE34728.1 - 3.9e-15 55.4 36.2 1.7e-14 53.3 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPE34728.1 - 7.9e-06 24.5 19.2 7.1e-05 21.3 3.0 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein PSII_Ycf12 PF05969.6 EPE34728.1 - 0.19 11.3 1.9 0.57 9.8 1.3 1.9 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 Beta-lactamase PF00144.19 EPE34729.1 - 1.3e-41 142.7 0.0 1.9e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EPE34729.1 - 0.027 13.7 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase AAA PF00004.24 EPE34730.1 - 9.3e-18 64.7 0.0 2.1e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE34730.1 - 0.00021 21.3 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE34730.1 - 0.0043 17.1 0.3 0.062 13.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EPE34730.1 - 0.0058 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE34730.1 - 0.0068 17.2 0.0 0.021 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPE34730.1 - 0.0091 15.7 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPE34730.1 - 0.015 15.0 0.3 0.036 13.8 0.2 1.5 1 0 0 1 1 1 0 Part of AAA domain Zot PF05707.7 EPE34730.1 - 0.018 14.5 0.2 0.26 10.7 0.1 2.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_33 PF13671.1 EPE34730.1 - 0.028 14.3 0.0 0.074 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EPE34730.1 - 0.065 13.5 0.1 0.38 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.2 EPE34732.1 - 7.5e-15 55.4 0.0 1.4e-14 54.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE34732.1 - 0.0002 21.0 0.0 0.00056 19.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.9 EPE34732.1 - 0.03 12.8 0.0 0.048 12.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.3 EPE34732.1 - 0.042 13.7 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_5 PF12695.2 EPE34732.1 - 0.053 13.2 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Fructosamin_kin PF03881.9 EPE34733.1 - 3.6e-28 98.3 0.0 1.3e-27 96.5 0.0 1.7 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EPE34733.1 - 0.019 14.7 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family adh_short PF00106.20 EPE34734.1 - 6.8e-20 71.6 0.3 1.9e-19 70.1 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE34734.1 - 2.3e-10 40.6 0.2 3e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE34734.1 - 1.4e-08 34.6 0.1 1.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPE34734.1 - 4e-05 23.6 0.0 0.00017 21.6 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPE34734.1 - 0.0002 20.3 0.2 0.00035 19.5 0.2 1.4 1 1 0 1 1 1 1 Male sterility protein Fungal_trans PF04082.13 EPE34735.1 - 7.1e-27 93.9 0.1 1.9e-26 92.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE34735.1 - 2.9e-05 23.8 12.1 4.5e-05 23.2 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 EPE34736.1 - 5e-87 292.5 0.0 6.5e-87 292.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Transp_cyt_pur PF02133.10 EPE34737.1 - 1.2e-103 347.0 36.2 1.5e-103 346.7 25.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PTR2 PF00854.16 EPE34738.1 - 3.5e-55 187.3 10.0 5.5e-55 186.6 6.9 1.4 1 0 0 1 1 1 1 POT family AAA PF00004.24 EPE34739.1 - 3.7e-15 56.2 0.0 7.1e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE34739.1 - 0.00092 19.2 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE34739.1 - 0.0012 18.9 0.1 0.017 15.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EPE34739.1 - 0.0046 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Zot PF05707.7 EPE34739.1 - 0.024 14.0 0.0 1.5 8.2 0.0 2.4 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_17 PF13207.1 EPE34739.1 - 0.035 14.9 0.5 0.24 12.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 EPE34739.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IPT PF01745.11 EPE34739.1 - 0.076 12.1 0.0 12 4.9 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_33 PF13671.1 EPE34739.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABM PF03992.11 EPE34740.1 - 0.021 14.8 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase UPF1_Zn_bind PF09416.5 EPE34741.1 - 1.3e-70 235.9 1.4 1.3e-70 235.9 1.0 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EPE34741.1 - 4.9e-60 202.3 0.0 9.1e-60 201.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPE34741.1 - 1.6e-57 194.8 1.0 2.4e-57 194.2 0.7 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE34741.1 - 2.1e-14 53.0 0.8 4.2e-14 52.0 0.1 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 EPE34741.1 - 1.8e-12 47.2 0.2 2.9e-11 43.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EPE34741.1 - 7.1e-09 35.7 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EPE34741.1 - 7.2e-05 22.4 0.3 0.32 10.4 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EPE34741.1 - 0.0005 19.1 0.1 0.0061 15.5 0.0 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 EPE34741.1 - 0.00086 18.9 0.0 0.002 17.7 0.0 1.7 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EPE34741.1 - 0.0013 17.8 0.0 0.42 9.4 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.16 EPE34741.1 - 0.0024 17.2 0.0 0.022 14.0 0.0 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EPE34741.1 - 0.0088 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase KaiC PF06745.8 EPE34741.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EPE34741.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPE34741.1 - 0.059 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EPE34741.1 - 0.089 12.9 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPE34741.1 - 0.1 12.5 0.1 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.11 EPE34741.1 - 0.14 11.3 0.0 0.35 10.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.1 EPE34741.1 - 0.15 12.1 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain SRP54 PF00448.17 EPE34741.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Brix PF04427.13 EPE34742.1 - 7.7e-45 152.8 0.6 9.9e-45 152.5 0.4 1.1 1 0 0 1 1 1 1 Brix domain Kri1 PF05178.7 EPE34742.1 - 0.072 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 KRI1-like family EamA PF00892.15 EPE34743.1 - 5.3e-13 49.1 24.7 7.7e-08 32.4 8.4 2.7 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EPE34743.1 - 1.9e-06 28.0 20.3 2.4e-05 24.4 0.2 3.4 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EPE34743.1 - 0.0002 21.0 14.3 0.003 17.2 4.3 2.6 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EPE34743.1 - 0.0026 16.9 2.6 0.005 15.9 0.0 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter SGL PF08450.7 EPE34744.1 - 0.0021 17.4 0.0 0.0056 16.0 0.1 1.7 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region GMC_oxred_N PF00732.14 EPE34745.1 - 6.9e-28 97.6 0.0 9.2e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE34745.1 - 4.7e-07 30.1 0.0 1.3e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 EPE34745.1 - 0.012 15.5 0.2 0.45 10.3 0.1 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE34745.1 - 0.013 14.4 0.2 0.036 12.9 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPE34745.1 - 0.028 14.4 0.1 0.069 13.1 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE34745.1 - 0.046 12.5 0.1 0.57 8.9 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 EPE34745.1 - 0.052 12.1 0.0 0.11 11.1 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase RTA1 PF04479.8 EPE34746.1 - 8.4e-37 126.8 3.5 1.2e-36 126.3 2.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 EPE34747.1 - 0.00015 21.6 11.1 0.00031 20.5 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE34747.1 - 0.00029 19.5 0.4 0.00043 18.9 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 EPE34748.1 - 1.2e-22 80.4 0.0 1.8e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF496 PF04363.7 EPE34749.1 - 0.014 15.2 0.1 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF496) Epimerase PF01370.16 EPE34749.1 - 0.042 13.2 0.0 0.079 12.3 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family YhdB PF14148.1 EPE34749.1 - 0.045 13.5 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 YhdB-like protein DUF2075 PF09848.4 EPE34751.1 - 6.2e-54 183.3 0.0 8.4e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EPE34751.1 - 1.7e-05 24.7 0.0 0.00028 20.7 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GIY-YIG PF01541.19 EPE34751.1 - 2.7e-05 24.4 0.0 7.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain MazG-like PF12643.2 EPE34751.1 - 4.2e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 MazG-like family MazG PF03819.12 EPE34751.1 - 0.00019 21.3 0.1 0.00048 20.0 0.1 1.7 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain AAA_19 PF13245.1 EPE34751.1 - 0.00043 19.9 0.0 0.0023 17.6 0.0 2.2 3 0 0 3 3 2 1 Part of AAA domain AAA_16 PF13191.1 EPE34751.1 - 0.0044 17.0 1.3 0.028 14.4 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPE34751.1 - 0.0065 16.6 0.1 0.069 13.2 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 EPE34751.1 - 0.012 15.8 0.0 0.22 11.6 0.0 2.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EPE34751.1 - 0.017 14.5 0.5 0.79 9.1 0.2 3.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.1 EPE34751.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EPE34751.1 - 0.028 13.9 0.1 0.27 10.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EPE34751.1 - 0.049 12.7 0.5 0.25 10.4 0.2 2.1 1 1 1 2 2 2 0 KaiC SNF2_N PF00176.18 EPE34751.1 - 0.051 12.3 0.1 0.45 9.2 0.0 2.3 2 1 0 3 3 3 0 SNF2 family N-terminal domain Zot PF05707.7 EPE34751.1 - 0.073 12.5 0.0 0.26 10.7 0.0 1.9 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) NACHT PF05729.7 EPE34751.1 - 0.084 12.5 0.2 0.32 10.6 0.2 2.2 2 1 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 EPE34751.1 - 0.093 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NUDIX PF00293.23 EPE34753.1 - 1.7e-14 53.6 0.1 7e-14 51.6 0.1 1.9 2 0 0 2 2 2 1 NUDIX domain Lipase_3 PF01764.20 EPE34753.1 - 0.0015 18.1 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF1680 PF07944.7 EPE34755.1 - 2.6e-127 425.2 0.9 3e-127 425.0 0.6 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) NAGLU_C PF12972.2 EPE34755.1 - 0.016 14.6 0.1 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Fungal_trans PF04082.13 EPE34757.1 - 2.9e-21 75.5 0.2 4.3e-21 74.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE34757.1 - 2.4e-08 33.7 11.8 4.1e-08 32.9 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 EPE34758.1 - 2.8e-24 84.9 0.2 5.6e-24 83.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE34758.1 - 1.5e-16 60.1 0.1 2.5e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.11 EPE34758.1 - 0.017 14.6 0.1 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EPE34758.1 - 0.026 14.6 0.1 0.066 13.3 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EPE34758.1 - 0.034 13.2 0.1 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EPE34758.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 EPE34758.1 - 0.077 13.4 0.2 0.26 11.7 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE34758.1 - 0.085 12.9 0.4 0.17 11.8 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EPE34758.1 - 0.11 12.3 1.9 0.21 11.3 1.3 1.4 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.14 EPE34758.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Aldedh PF00171.17 EPE34759.1 - 4.5e-150 500.0 1.7 6.1e-150 499.5 1.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldo_ket_red PF00248.16 EPE34759.1 - 1.8e-31 109.0 0.1 3e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Pyr_redox_3 PF13738.1 EPE34759.1 - 2.9e-22 79.7 0.0 5.5e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE34759.1 - 4.1e-11 42.7 0.0 1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EPE34759.1 - 6.8e-08 31.1 0.5 3.9e-06 25.3 0.2 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPE34759.1 - 6.9e-07 28.5 0.3 5.2e-05 22.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EPE34759.1 - 0.0012 17.8 0.0 0.39 9.5 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPE34759.1 - 0.0049 16.6 0.0 0.041 13.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPE34759.1 - 0.0085 15.9 0.0 0.054 13.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.1 EPE34760.1 - 5.5e-26 91.8 0.0 6.9e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE34760.1 - 1.8e-25 89.8 0.1 2.4e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE34760.1 - 1.6e-12 47.4 0.0 3.1e-12 46.5 0.0 1.5 1 1 0 1 1 1 1 KR domain SUFU PF05076.8 EPE34761.1 - 0.11 12.1 0.0 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Suppressor of fused protein (SUFU) DUF4372 PF14294.1 EPE34761.1 - 0.15 11.9 0.1 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) Glyco_hydro_30 PF02055.11 EPE34762.1 - 2e-13 49.3 0.2 5.2e-08 31.5 0.2 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EPE34762.1 - 1.5e-08 34.0 1.5 2.6e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Mnd1 PF03962.10 EPE34763.1 - 3.6 7.2 7.1 3.8 7.1 2.2 2.0 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 EPE34763.1 - 9 5.8 8.6 2.2 7.8 2.5 2.0 2 0 0 2 2 2 0 IncA protein Amidohydro_4 PF13147.1 EPE34765.1 - 4.1e-16 59.8 0.9 2.9e-15 57.0 0.6 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EPE34765.1 - 8.2e-15 55.2 0.2 2.5e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EPE34765.1 - 1.1e-08 34.7 0.1 2.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPE34765.1 - 2.3e-08 33.7 0.4 3.4e-07 29.8 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase family Fungal_trans PF04082.13 EPE34766.1 - 9.8e-08 31.1 5.6 7.6e-07 28.2 3.9 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 EPE34768.1 - 2.4e-43 148.3 0.0 3.8e-43 147.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 EPE34769.1 - 5.9e-22 78.6 0.2 9.9e-22 77.8 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE34769.1 - 3.8e-18 65.9 3.7 2.3e-17 63.4 2.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE34769.1 - 8.1e-08 32.1 3.1 1.6e-06 27.9 0.2 2.2 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EPE34769.1 - 0.00083 18.3 0.1 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EPE34769.1 - 0.0055 16.1 0.2 0.013 14.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 EPE34769.1 - 0.01 16.0 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EPE34769.1 - 0.026 14.5 1.1 0.53 10.2 0.5 2.6 2 1 0 2 2 2 0 NADH(P)-binding 3HCDH_N PF02737.13 EPE34769.1 - 0.085 12.5 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EPE34769.1 - 0.093 12.8 0.9 1.7 8.7 0.6 2.4 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAT PF03417.11 EPE34770.1 - 4.1e-29 101.6 0.0 5.1e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase MFS_1 PF07690.11 EPE34771.1 - 3.3e-33 114.8 30.7 2.3e-32 112.1 21.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 EPE34771.1 - 0.0019 18.1 11.8 0.1 12.6 1.2 3.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1228) DUF1129 PF06570.6 EPE34771.1 - 0.0089 15.3 0.1 0.0089 15.3 0.1 3.6 2 2 3 5 5 5 1 Protein of unknown function (DUF1129) Amidohydro_1 PF01979.15 EPE34772.1 - 1.1e-07 31.8 0.1 2.7e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Fungal_trans PF04082.13 EPE34773.1 - 1.2e-14 53.8 1.2 3.4e-14 52.3 0.1 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE34773.1 - 1e-05 25.3 10.5 1.8e-05 24.5 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EPE34774.1 - 2.9e-99 332.7 18.3 3.8e-99 332.3 12.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE34774.1 - 5e-30 104.3 46.3 2.1e-27 95.7 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EPE34774.1 - 3.2e-07 28.7 1.2 3.2e-07 28.7 0.8 2.6 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EPE34774.1 - 0.063 11.3 4.2 0.019 13.1 0.6 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector FAD_binding_3 PF01494.14 EPE34775.1 - 4.4e-07 29.2 5.2 4.1e-05 22.8 3.6 2.9 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EPE34775.1 - 0.007 15.0 1.5 3.8 6.0 0.0 3.0 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 EPE34775.1 - 0.0076 16.1 0.0 0.046 13.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE34775.1 - 0.012 14.5 0.3 0.25 10.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPE34775.1 - 0.013 15.5 1.0 0.039 13.9 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPE34775.1 - 0.033 14.6 1.6 0.062 13.7 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EPE34775.1 - 0.051 12.6 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EPE34775.1 - 0.06 13.1 0.3 0.63 9.7 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EPE34775.1 - 0.073 11.5 0.9 0.12 10.8 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EPE34775.1 - 0.085 12.4 0.2 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 EPE34775.1 - 0.12 11.1 0.0 0.37 9.5 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.19 EPE34775.1 - 0.13 11.1 2.0 0.25 10.2 0.5 1.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase Pkinase PF00069.20 EPE34776.1 - 1.4e-14 53.8 0.0 2.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE34776.1 - 1.2e-08 34.3 0.0 1.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPE34776.1 - 1.7e-05 24.6 0.0 2.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE34776.1 - 0.0089 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EPE34776.1 - 0.022 14.0 0.1 0.063 12.6 0.0 1.7 1 1 1 2 2 2 0 RIO1 family Kdo PF06293.9 EPE34776.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HATPase_c_3 PF13589.1 EPE34777.1 - 1.1e-17 63.9 0.0 2.5e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EPE34777.1 - 6e-10 38.8 0.0 4.6e-09 36.0 0.0 2.3 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EPE34777.1 - 0.005 16.5 0.0 0.016 14.9 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Polysacc_syn_2C PF08485.5 EPE34777.1 - 0.14 11.6 0.2 0.82 9.2 0.5 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal Cu-oxidase PF00394.17 EPE34779.1 - 5.3e-34 117.4 0.0 1.4e-29 103.0 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EPE34779.1 - 2.5e-30 104.6 1.1 2.8e-29 101.2 0.0 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPE34779.1 - 5.7e-22 77.7 6.0 3.4e-20 71.9 0.5 3.6 3 1 0 3 3 3 2 Multicopper oxidase Glyco_hydro_76 PF03663.9 EPE34780.1 - 7.2e-41 140.7 18.2 9.2e-41 140.4 12.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 P5CR_dimer PF14748.1 EPE34781.1 - 3.7e-25 88.0 0.0 7.3e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EPE34781.1 - 2.4e-12 47.1 0.3 7e-12 45.6 0.2 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1996 PF09362.5 EPE34782.1 - 1.5e-83 280.0 0.1 1.5e-83 280.0 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Kelch_5 PF13854.1 EPE34783.1 - 4.3e-13 48.8 13.9 4.3e-11 42.5 0.5 5.6 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 EPE34783.1 - 0.0034 17.5 14.2 0.29 11.3 0.2 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EPE34783.1 - 0.0053 16.8 14.2 2.1 8.6 0.2 5.7 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 EPE34783.1 - 0.97 9.3 7.9 55 3.7 0.0 5.3 5 0 0 5 5 5 0 Kelch motif SprT-like PF10263.4 EPE34786.1 - 9e-09 35.1 0.5 8.9e-08 31.9 0.3 2.4 1 1 0 1 1 1 1 SprT-like family adh_short PF00106.20 EPE34789.1 - 1.5e-16 60.8 0.0 2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE34789.1 - 3.4e-08 33.3 0.0 5.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Phage_lysis PF03245.8 EPE34789.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein CENP-N PF05238.8 EPE34790.1 - 1.9e-130 435.5 0.0 2.2e-130 435.3 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like p450 PF00067.17 EPE34792.1 - 9.2e-70 235.4 0.0 1.4e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EPE34792.1 - 1e-29 103.4 20.9 1e-29 103.4 14.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE34792.1 - 0.00011 20.6 2.5 0.00017 19.9 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAA_hydrolase PF01557.13 EPE34793.1 - 1.8e-51 174.6 0.0 2.6e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EPE34793.1 - 5.9e-07 29.4 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal FAD_binding_3 PF01494.14 EPE34794.1 - 2.4e-20 72.8 0.1 7.4e-20 71.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.6 EPE34794.1 - 4e-14 52.5 0.0 7.2e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) DAO PF01266.19 EPE34794.1 - 1.5e-08 33.9 0.4 2.3e-07 30.0 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE34794.1 - 7.8e-07 29.0 0.1 1.8e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE34794.1 - 1.2e-06 27.6 0.4 1.8e-06 27.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EPE34794.1 - 3.9e-06 26.8 0.5 9.1e-06 25.6 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE34794.1 - 7.8e-05 22.8 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPE34794.1 - 0.00012 21.3 0.2 0.00019 20.6 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EPE34794.1 - 0.00012 20.9 0.1 0.016 13.8 0.1 2.3 1 1 0 2 2 2 1 Tryptophan halogenase Amino_oxidase PF01593.19 EPE34794.1 - 0.00016 20.8 0.2 0.16 10.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.17 EPE34794.1 - 0.00027 19.9 0.0 0.00046 19.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EPE34794.1 - 0.00041 19.5 0.0 0.0008 18.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EPE34794.1 - 0.00077 18.4 0.8 0.0054 15.6 0.6 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EPE34794.1 - 0.0012 17.4 1.0 0.0021 16.6 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EPE34794.1 - 0.0051 17.1 0.2 0.015 15.7 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EPE34794.1 - 0.0099 15.4 0.3 0.046 13.2 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EPE34794.1 - 0.046 13.1 0.3 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 EPE34794.1 - 0.056 13.2 1.7 4.7 6.9 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Aldedh PF00171.17 EPE34796.1 - 2.6e-07 29.3 0.0 0.0098 14.2 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Fungal_trans PF04082.13 EPE34797.1 - 2.4e-08 33.1 0.1 4.9e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EPE34797.1 - 3.5e-08 33.2 13.8 0.00047 20.2 2.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE34797.1 - 2.4e-07 30.6 14.8 0.003 17.8 2.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPE34797.1 - 0.00016 21.7 13.1 0.002 18.3 3.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain Zn_clus PF00172.13 EPE34797.1 - 0.00036 20.3 10.5 0.00036 20.3 7.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.3 EPE34797.1 - 1.6 8.9 8.1 3.7 7.8 1.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding LigB PF02900.13 EPE34798.1 - 1.6e-24 86.3 0.1 1.8e-24 86.1 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PepX_C PF08530.5 EPE34799.1 - 5.1e-43 147.4 0.4 8.1e-43 146.8 0.3 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 EPE34799.1 - 4.1e-41 141.2 0.1 6e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EPE34799.1 - 1.4e-06 28.3 0.2 2.8e-06 27.3 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE34799.1 - 7.2e-05 22.5 0.1 0.00041 20.1 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family IN_DBD_C PF00552.16 EPE34799.1 - 0.0068 15.8 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Integrase DNA binding domain Hydrolase_4 PF12146.3 EPE34799.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Cupin_2 PF07883.6 EPE34800.1 - 3.7e-08 32.7 0.1 6e-07 28.8 0.0 2.1 1 1 1 2 2 2 1 Cupin domain Cupin_3 PF05899.7 EPE34800.1 - 0.0054 16.0 0.3 0.22 10.9 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF861) Bac_rhamnosid PF05592.6 EPE34801.1 - 6.1e-15 54.4 0.1 7.2e-15 54.1 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase F-box PF00646.28 EPE34802.1 - 0.00021 20.8 0.7 0.00065 19.2 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE34802.1 - 0.008 15.8 0.1 0.008 15.8 0.1 2.3 2 0 0 2 2 2 1 F-box-like Transposase_21 PF02992.9 EPE34803.1 - 0.16 11.0 1.0 0.27 10.2 0.7 1.3 1 0 0 1 1 1 0 Transposase family tnp2 Pro_CA PF00484.14 EPE34804.1 - 4.6e-20 72.1 0.0 5.5e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DUF221 PF02714.10 EPE34805.1 - 5.5e-109 363.9 17.2 5.5e-109 363.9 11.9 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPE34805.1 - 5.8e-42 142.9 0.6 5.8e-42 142.9 0.4 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EPE34805.1 - 4.1e-21 74.6 0.0 1.2e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EPE34805.1 - 8.2e-16 58.2 2.0 8.2e-16 58.2 1.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) CN_hydrolase PF00795.17 EPE34806.1 - 1.5e-18 66.8 0.0 2.3e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TatD_DNase PF01026.16 EPE34808.1 - 4.1e-55 186.7 0.0 4.7e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EPE34808.1 - 0.021 14.3 0.0 0.32 10.5 0.0 2.6 2 1 0 2 2 2 0 Amidohydrolase bZIP_2 PF07716.10 EPE34809.1 - 2e-11 43.5 10.5 3.1e-11 42.8 7.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EPE34809.1 - 6.6e-05 22.7 11.9 0.00018 21.4 8.2 1.7 1 1 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 EPE34809.1 - 0.0025 17.6 3.3 0.0047 16.8 2.3 1.5 1 0 0 1 1 1 1 Haemolysin XhlA IncA PF04156.9 EPE34809.1 - 0.0065 16.0 3.9 0.0095 15.5 2.7 1.2 1 0 0 1 1 1 1 IncA protein TSC22 PF01166.13 EPE34809.1 - 0.026 14.4 0.6 0.05 13.5 0.4 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Fzo_mitofusin PF04799.8 EPE34809.1 - 0.91 8.8 3.9 0.41 10.0 1.3 1.4 2 0 0 2 2 2 0 fzo-like conserved region HAUS6_N PF14661.1 EPE34809.1 - 3.2 7.0 8.7 4.5 6.5 6.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF972 PF06156.8 EPE34809.1 - 3.7 7.9 5.8 3.6 7.9 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HET PF06985.6 EPE34810.1 - 1.4e-25 90.0 0.0 3.3e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4470 PF14737.1 EPE34811.1 - 1.8e-05 24.3 1.5 2.5e-05 23.9 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) XLF PF09302.6 EPE34811.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 XLF (XRCC4-like factor) Grp1_Fun34_YaaH PF01184.14 EPE34812.1 - 4.7e-22 78.3 30.0 6.5e-22 77.8 20.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family VEFS-Box PF09733.4 EPE34814.1 - 0.048 13.3 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 VEFS-Box of polycomb protein DUF3293 PF11697.3 EPE34818.1 - 0.083 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) EBP PF05241.7 EPE34819.1 - 0.26 10.2 7.0 0.42 9.5 4.5 1.7 1 1 0 1 1 1 0 Emopamil binding protein Pkinase PF00069.20 EPE34820.1 - 7.5e-05 22.0 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EPE34820.1 - 0.09 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family COX4 PF02936.9 EPE34822.1 - 0.0098 15.6 0.7 0.013 15.2 0.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF485 PF04341.7 EPE34822.1 - 0.081 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 PAN_2 PF08276.6 EPE34823.1 - 0.099 12.4 0.5 0.19 11.6 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain Chorismate_synt PF01264.16 EPE34825.1 - 3.7e-126 420.2 0.0 4.6e-126 419.9 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.14 EPE34826.1 - 5e-15 55.6 0.0 1.5e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Zip PF02535.17 EPE34828.1 - 5.5e-57 193.1 3.4 1.2e-56 192.0 2.4 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter PNPOx_C PF10590.4 EPE34829.1 - 1.7e-20 72.1 2.7 1.7e-20 72.1 1.9 2.1 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EPE34829.1 - 4e-18 65.2 0.0 6e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EPE34829.1 - 0.0005 20.3 0.5 0.0013 19.0 0.4 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3327 PF11806.3 EPE34829.1 - 0.077 13.3 0.8 4.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3327) Peptidase_C12 PF01088.16 EPE34830.1 - 8.1e-64 214.7 0.0 1e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 CBM_1 PF00734.13 EPE34831.1 - 1.2e-07 31.3 10.5 1.2e-07 31.3 7.3 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain adh_short PF00106.20 EPE34833.1 - 1.7e-13 50.8 0.7 2.5e-13 50.3 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE34833.1 - 9.5e-06 25.3 0.3 1.5e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 KR domain FTR PF01913.13 EPE34833.1 - 0.046 13.4 0.1 0.086 12.5 0.1 1.4 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Ank_2 PF12796.2 EPE34834.1 - 1.7e-41 140.4 9.0 1.4e-18 66.9 0.6 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPE34834.1 - 4.7e-27 92.4 1.9 6e-07 28.9 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EPE34834.1 - 1.3e-20 73.3 0.1 1.7e-09 37.9 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE34834.1 - 4.3e-16 57.4 1.3 0.0011 19.0 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EPE34834.1 - 2e-15 56.4 5.9 3.1e-05 24.0 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) bZIP_1 PF00170.16 EPE34834.1 - 0.0013 18.6 3.5 0.0022 17.9 2.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPE34834.1 - 0.0079 16.0 1.5 0.013 15.2 1.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPE34834.1 - 0.056 13.7 1.7 0.099 12.9 1.2 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor CPL PF08144.6 EPE34834.1 - 0.09 12.6 0.2 0.37 10.6 0.0 2.1 2 1 0 2 2 2 0 CPL (NUC119) domain adh_short PF00106.20 EPE34835.1 - 3.8e-17 62.6 0.3 1.6e-16 60.6 0.1 1.9 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE34835.1 - 2.9e-09 36.8 0.1 4.2e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE34835.1 - 0.00012 21.5 0.5 0.00033 20.1 0.1 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EPE34835.1 - 0.00067 19.4 0.0 0.00097 18.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase IMPDH PF00478.20 EPE34835.1 - 0.0064 15.4 0.0 0.0083 15.0 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NAD_binding_10 PF13460.1 EPE34835.1 - 0.015 15.2 0.1 0.042 13.8 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding Pterin_bind PF00809.17 EPE34835.1 - 0.025 13.9 0.2 0.063 12.6 0.1 1.6 1 1 0 1 1 1 0 Pterin binding enzyme Hexapep PF00132.19 EPE34836.1 - 6.5e-12 44.3 16.7 6e-08 31.8 3.8 3.8 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EPE34836.1 - 3.9e-11 42.3 18.2 8.8e-09 34.7 4.2 3.6 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EPE34836.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Laminin_II PF06009.7 EPE34839.1 - 0.09 12.5 0.2 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF1681 PF07933.9 EPE34840.1 - 1.4e-59 200.1 0.0 2.2e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Apocytochr_F_C PF01333.14 EPE34840.1 - 0.097 12.5 0.3 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 Apocytochrome F, C-terminal IF-2B PF01008.12 EPE34841.1 - 2.1e-49 168.0 0.0 2.4e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1942 PF09167.6 EPE34841.1 - 0.034 13.9 0.4 0.098 12.4 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1942) Oxidored_molyb PF00174.14 EPE34842.1 - 1.6e-50 170.8 0.0 2.5e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EPE34842.1 - 4.6e-26 90.9 2.3 7.9e-26 90.2 1.6 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain UpxZ PF06603.6 EPE34843.1 - 0.14 12.1 1.0 1.9 8.5 0.1 2.7 3 0 0 3 3 3 0 UpxZ family of transcription anti-terminator antagonists DUF3959 PF13105.1 EPE34843.1 - 0.28 10.4 6.5 0.45 9.8 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Atg14 PF10186.4 EPE34843.1 - 1.9 7.3 15.6 3.6 6.4 10.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pyr_redox_2 PF07992.9 EPE34844.1 - 2.5e-21 76.4 0.0 3.7e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE34844.1 - 5.4e-13 49.1 1.9 1.2e-09 38.4 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EPE34844.1 - 1.1e-06 27.5 0.1 1.1e-05 24.3 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EPE34844.1 - 1.7e-05 24.8 0.1 5.2e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPE34844.1 - 7.5e-05 22.2 0.2 0.00031 20.3 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EPE34844.1 - 9.8e-05 21.5 0.9 0.00031 19.9 0.1 2.2 2 0 0 2 2 2 1 EF hand CLTH PF10607.4 EPE34845.1 - 3.5e-34 117.5 0.0 4.8e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EPE34845.1 - 1.2e-09 37.5 0.0 2.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 LisH PRK PF00485.13 EPE34846.1 - 6.7e-60 201.9 0.0 1.1e-59 201.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EPE34846.1 - 3.9e-45 153.6 0.0 5.7e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EPE34846.1 - 6.3e-10 39.9 0.1 1.9e-09 38.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPE34846.1 - 1e-05 25.8 0.1 3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 EPE34846.1 - 8.3e-05 22.2 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EPE34846.1 - 0.00027 20.8 0.0 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPE34846.1 - 0.0012 19.1 0.1 0.017 15.3 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EPE34846.1 - 0.0058 16.1 0.2 0.014 14.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EPE34846.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 EPE34846.1 - 0.019 14.6 0.0 0.054 13.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pribosyltran PF00156.22 EPE34846.1 - 0.019 14.7 0.0 0.074 12.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosyl transferase domain AAA_16 PF13191.1 EPE34846.1 - 0.02 14.9 0.0 0.053 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 EPE34846.1 - 0.025 14.3 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EPE34846.1 - 0.041 13.3 0.1 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family APS_kinase PF01583.15 EPE34846.1 - 0.049 13.2 0.0 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.17 EPE34846.1 - 0.092 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 EPE34846.1 - 0.097 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 EPE34846.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DSPc PF00782.15 EPE34848.1 - 9.6e-20 70.5 0.0 1.2e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPE34848.1 - 0.00057 19.2 0.0 0.00084 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EPE34848.1 - 0.00097 19.4 0.3 0.51 10.5 0.1 2.3 1 1 1 2 2 2 2 Tyrosine phosphatase family Pribosyltran PF00156.22 EPE34848.1 - 0.029 14.0 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Lipase_3 PF01764.20 EPE34849.1 - 5.6e-09 35.7 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EPE34849.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EPE34849.1 - 0.033 13.7 0.5 0.097 12.2 0.3 2.0 1 1 0 1 1 1 0 PGAP1-like protein DLH PF01738.13 EPE34849.1 - 0.082 12.1 0.0 0.19 10.9 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Flavi_DEAD PF07652.9 EPE34851.1 - 0.0008 19.1 1.3 0.41 10.3 0.1 2.2 2 0 0 2 2 2 2 Flavivirus DEAD domain Mus7 PF09462.5 EPE34851.1 - 0.01 14.7 1.1 1.6 7.4 0.1 2.1 2 0 0 2 2 2 0 Mus7/MMS22 family DNA_pol3_a_NI PF14480.1 EPE34851.1 - 0.029 14.0 0.0 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I P3A PF08727.6 EPE34851.1 - 0.035 13.4 0.4 4.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Poliovirus 3A protein like Thioredoxin PF00085.15 EPE34851.1 - 0.14 11.8 2.4 3.7 7.2 0.2 2.6 2 0 0 2 2 2 0 Thioredoxin ECM11 PF15463.1 EPE34851.1 - 3.8 7.7 6.5 7.3 6.8 0.7 2.4 2 0 0 2 2 2 0 Extracellular mutant protein 11 LXG PF04740.7 EPE34851.1 - 4.3 7.0 8.3 12 5.6 0.2 2.7 3 0 0 3 3 3 0 LXG domain of WXG superfamily zf-C2H2_4 PF13894.1 EPE34853.1 - 1.2e-05 25.2 16.8 0.00015 21.8 0.9 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE34853.1 - 0.00042 20.4 1.0 0.00042 20.4 0.7 3.7 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-met PF12874.2 EPE34853.1 - 0.051 13.8 0.1 0.051 13.8 0.1 2.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EPE34853.1 - 0.35 11.0 8.8 15 5.7 4.1 3.5 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) MFS_1 PF07690.11 EPE34854.1 - 3.9e-46 157.3 32.7 6.4e-46 156.6 22.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily OTU PF02338.14 EPE34855.1 - 9.6e-19 68.1 1.5 3.9e-18 66.1 0.0 2.4 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EPE34855.1 - 0.00063 19.1 0.0 0.46 9.7 0.0 2.6 2 1 1 3 3 3 2 Peptidase C65 Otubain TPMT PF05724.6 EPE34856.1 - 5.2e-27 94.6 0.0 6.7e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 EPE34856.1 - 2e-05 24.3 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE34856.1 - 0.00014 22.3 0.0 0.00034 21.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE34856.1 - 0.00026 20.6 0.0 0.0021 17.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE34856.1 - 0.00035 20.5 0.0 0.0007 19.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EPE34856.1 - 0.073 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase N2227 PF07942.7 EPE34856.1 - 0.17 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein adh_short PF00106.20 EPE34857.1 - 2.1e-24 86.2 0.0 2.7e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE34857.1 - 1.8e-22 80.2 0.0 2.7e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE34857.1 - 2.1e-07 30.7 0.0 3.3e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 KR domain AMP-binding PF00501.23 EPE34858.1 - 1.7e-77 260.5 0.0 2.1e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE34858.1 - 6.6e-17 62.2 0.1 2.1e-14 54.2 0.0 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Ank_2 PF12796.2 EPE34859.1 - 2.4e-77 255.3 19.8 3.5e-16 59.3 0.1 7.9 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EPE34859.1 - 1.2e-59 195.3 26.6 6.2e-05 22.6 0.1 15.6 15 0 0 15 15 15 12 Ankyrin repeat Ank_3 PF13606.1 EPE34859.1 - 7.7e-47 152.6 11.9 0.0027 17.8 0.0 16.2 16 0 0 16 16 16 10 Ankyrin repeat Ank_4 PF13637.1 EPE34859.1 - 1e-45 153.2 15.5 4.4e-07 30.2 0.0 11.7 5 2 7 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE34859.1 - 6.5e-34 115.1 21.9 1e-06 28.7 0.2 13.0 7 4 5 13 13 13 8 Ankyrin repeats (many copies) Clr5 PF14420.1 EPE34859.1 - 6.8e-11 41.8 5.5 8.8e-11 41.5 1.9 2.4 2 0 0 2 2 2 1 Clr5 domain DUF3734 PF12536.3 EPE34859.1 - 0.0051 16.9 0.0 0.044 13.9 0.0 2.5 3 0 0 3 3 3 1 Patatin phospholipase SHMT PF00464.14 EPE34861.1 - 2.8e-194 645.0 0.0 3.3e-194 644.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EPE34861.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Ribosomal_L19e PF01280.15 EPE34862.1 - 5.2e-61 204.7 7.4 5.2e-61 204.7 5.1 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EPE34862.1 - 0.033 13.4 1.4 0.035 13.3 0.9 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Sec62 PF03839.11 EPE34862.1 - 0.39 10.0 3.9 37 3.6 0.0 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 DUF4337 PF14235.1 EPE34862.1 - 6.5 6.5 8.1 10 5.9 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3554 PF12074.3 EPE34863.1 - 2.3e-84 283.7 10.4 1.4e-82 277.8 2.7 5.2 6 0 0 6 6 6 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 EPE34863.1 - 2e-36 124.1 47.7 5.2e-10 39.4 0.0 17.2 11 3 7 19 19 18 11 HEAT repeats HEAT PF02985.17 EPE34863.1 - 7.6e-35 115.8 34.2 0.022 14.8 0.0 21.5 25 0 0 25 25 24 9 HEAT repeat HEAT_EZ PF13513.1 EPE34863.1 - 1.9e-32 110.8 51.2 5.5e-06 26.6 0.0 22.5 19 4 7 26 26 26 11 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPE34863.1 - 3e-15 56.3 0.0 1.1 9.6 0.0 9.7 8 3 4 12 12 11 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EPE34863.1 - 8.9e-12 44.0 4.0 0.076 11.3 0.0 8.7 8 3 3 11 11 11 4 Adaptin N terminal region Cnd1 PF12717.2 EPE34863.1 - 2.3e-11 43.8 1.5 0.4 10.4 0.0 9.5 7 2 2 10 10 10 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EPE34863.1 - 5.1e-10 39.5 3.4 0.0014 18.5 0.0 6.1 6 1 1 7 7 7 2 Parkin co-regulated protein FANCI_S2 PF14676.1 EPE34863.1 - 1.1e-05 25.3 0.0 0.7 9.7 0.0 5.0 4 0 0 4 4 4 1 FANCI solenoid 2 Ipi1_N PF12333.3 EPE34863.1 - 7.8e-05 22.5 1.5 0.51 10.3 0.0 6.0 5 1 0 5 5 4 1 Rix1 complex component involved in 60S ribosome maturation RasGEF_N_2 PF14663.1 EPE34863.1 - 0.018 14.9 0.0 1.1 9.1 0.0 3.5 3 0 0 3 3 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MMS19_C PF12460.3 EPE34863.1 - 0.65 8.6 16.3 1.2 7.7 0.0 6.0 6 1 0 6 6 6 0 RNAPII transcription regulator C-terminal HA2 PF04408.18 EPE34864.1 - 2.2e-17 62.9 0.0 7.1e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPE34864.1 - 3.3e-12 46.0 0.0 8.1e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPE34864.1 - 1.4e-10 40.9 0.1 3.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPE34864.1 - 1.3e-08 35.0 0.2 1.1e-07 32.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.11 EPE34864.1 - 4.1e-08 33.0 0.0 1.1e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.1 EPE34864.1 - 0.0003 20.2 0.0 0.00099 18.5 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EPE34864.1 - 0.0021 18.3 0.1 0.012 15.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.17 EPE34864.1 - 0.0031 16.4 0.0 0.0071 15.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 EPE34864.1 - 0.004 16.8 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EPE34864.1 - 0.011 15.1 0.0 0.061 12.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family KaiC PF06745.8 EPE34864.1 - 0.012 14.7 0.0 0.031 13.4 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 EPE34864.1 - 0.4 10.9 0.0 0.4 10.9 0.0 3.2 5 0 0 5 5 4 0 AAA domain Epimerase PF01370.16 EPE34865.1 - 9.4e-17 61.2 0.1 1.8e-16 60.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE34865.1 - 1.2e-13 50.3 0.0 4.5e-13 48.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPE34865.1 - 2.5e-10 40.6 0.2 7.5e-10 39.1 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPE34865.1 - 7e-06 25.1 0.0 6.6e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EPE34865.1 - 7.2e-06 25.4 0.1 2.6e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EPE34865.1 - 4.3e-05 23.4 3.2 9.8e-05 22.3 0.2 2.4 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPE34865.1 - 0.00012 21.1 0.2 0.00018 20.4 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PqqD PF05402.7 EPE34865.1 - 0.032 14.2 0.0 15 5.7 0.0 2.8 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) KR PF08659.5 EPE34865.1 - 0.043 13.4 1.8 0.42 10.2 0.3 2.4 2 1 0 2 2 2 0 KR domain GCHY-1 PF02649.9 EPE34866.1 - 0.17 11.1 1.1 0.24 10.5 0.7 1.3 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 Mcp5_PH PF12814.2 EPE34867.1 - 1.9e-48 163.4 0.0 4.9e-48 162.1 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DivIC PF04977.10 EPE34867.1 - 0.33 10.4 2.8 0.45 10.0 1.1 1.9 1 1 0 1 1 1 0 Septum formation initiator IncA PF04156.9 EPE34867.1 - 2.7 7.5 11.5 5.2 6.6 7.9 1.4 1 0 0 1 1 1 0 IncA protein UPF0242 PF06785.6 EPE34867.1 - 8.3 4.9 5.2 14 4.2 3.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) HAD_2 PF13419.1 EPE34868.1 - 1.1e-19 71.3 0.0 1.7e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE34868.1 - 2.5e-06 27.1 0.0 4.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EPE34868.1 - 4.3e-06 27.2 0.0 8.5e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2947 PF11163.3 EPE34868.1 - 0.054 13.0 0.9 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2947) YrhK PF14145.1 EPE34869.1 - 0.00092 18.8 22.5 0.94 9.1 0.1 4.9 3 2 0 3 3 3 3 YrhK-like protein DUF1049 PF06305.6 EPE34869.1 - 0.017 14.5 0.4 0.017 14.5 0.3 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) HET PF06985.6 EPE34871.1 - 1.1e-27 96.9 0.2 1.7e-27 96.2 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PALP PF00291.20 EPE34872.1 - 4.4e-64 216.6 0.7 5.6e-64 216.2 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Transglut_core PF01841.14 EPE34872.1 - 0.01 16.0 0.1 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DFP PF04127.10 EPE34872.1 - 0.029 14.0 0.3 0.051 13.2 0.2 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein IlvN PF07991.7 EPE34873.1 - 8.7e-47 158.5 0.1 1.3e-46 157.9 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EPE34873.1 - 1.6e-44 151.3 0.0 2.4e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EPE34873.1 - 0.013 15.8 0.0 0.036 14.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Chitin_synth_1 PF01644.12 EPE34874.1 - 1e-68 230.2 0.0 1.6e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase UQ_con PF00179.21 EPE34874.1 - 2.6e-36 124.1 0.0 4.6e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1N PF08407.6 EPE34874.1 - 2.2e-26 91.3 0.1 5e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EPE34874.1 - 7.8e-23 80.6 0.0 1.6e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EPE34874.1 - 3.4e-11 43.2 0.0 3.4e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPE34874.1 - 2.2e-07 30.9 0.0 4.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Opy2 PF09463.5 EPE34875.1 - 3e-05 24.0 23.2 4.6e-05 23.4 16.1 1.3 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 EPE34875.1 - 0.0053 16.3 0.1 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Glt_symporter PF03616.9 EPE34875.1 - 0.031 12.7 0.0 0.043 12.3 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter P12 PF12669.2 EPE34875.1 - 0.36 11.0 0.2 0.36 11.0 0.1 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family Ras PF00071.17 EPE34876.1 - 7.8e-53 178.1 0.0 1.6e-52 177.1 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EPE34876.1 - 2.5e-17 63.4 0.1 1.6e-15 57.6 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPE34876.1 - 0.00014 21.1 0.1 0.00054 19.2 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EPE34876.1 - 0.0047 16.8 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE34876.1 - 0.011 15.0 0.0 0.19 10.9 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.5 EPE34876.1 - 0.015 14.5 0.0 0.49 9.6 0.0 2.3 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPE34876.1 - 0.026 13.6 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ferritin_2 PF13668.1 EPE34877.1 - 7.8e-14 51.7 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain PIR PF00399.14 EPE34877.1 - 4.1e-06 25.9 5.1 4.1e-06 25.9 3.6 3.5 2 1 1 3 3 3 2 Yeast PIR protein repeat Ferritin-like PF12902.2 EPE34877.1 - 0.091 12.3 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Ferritin-like Hamartin PF04388.7 EPE34878.1 - 1.4e-39 136.3 22.9 7.5e-39 133.9 15.7 2.1 1 1 0 1 1 1 1 Hamartin protein DLH PF01738.13 EPE34878.1 - 9.4e-27 93.7 0.0 2.3e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPE34878.1 - 3.1e-06 27.0 0.0 8.2e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L23 PF00276.15 EPE34879.1 - 2.1e-11 43.5 0.0 4.4e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L23 DUF3770 PF12603.3 EPE34879.1 - 0.028 13.5 0.1 0.04 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) MT-A70 PF05063.9 EPE34880.1 - 9.2e-35 119.7 0.2 1.5e-34 119.0 0.1 1.4 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 EPE34880.1 - 0.0061 16.5 0.0 0.03 14.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Mito_carr PF00153.22 EPE34881.1 - 4.2e-60 199.4 0.1 3.3e-21 74.8 0.2 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein polyprenyl_synt PF00348.12 EPE34883.1 - 1.5e-37 128.8 0.2 7.9e-36 123.2 0.0 2.8 2 1 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EPE34883.1 - 7.5e-05 22.0 0.1 0.002 17.4 0.0 2.3 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Tim17 PF02466.14 EPE34885.1 - 1.7e-33 115.3 6.9 2.1e-33 115.0 4.8 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 EPE34885.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.6 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal adh_short_C2 PF13561.1 EPE34886.1 - 5.6e-30 104.8 0.0 7.7e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE34886.1 - 6.2e-29 101.0 0.2 8.6e-29 100.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE34886.1 - 8.6e-14 51.5 0.2 1.3e-13 50.9 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE34886.1 - 0.038 13.4 0.1 0.11 11.8 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EPE34886.1 - 0.041 13.5 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DMPK_coil PF08826.5 EPE34887.1 - 0.055 13.3 0.2 0.09 12.6 0.1 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like P5-ATPase PF12409.3 EPE34887.1 - 0.11 12.3 0.4 0.13 12.1 0.3 1.0 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF2360 PF10152.4 EPE34887.1 - 0.13 12.5 0.6 0.15 12.3 0.4 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Fungal_trans PF04082.13 EPE34888.1 - 2.2e-06 26.7 0.6 2.2e-06 26.7 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE34888.1 - 0.00021 21.0 7.8 0.00048 19.9 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EPE34889.1 - 2.3e-07 30.5 8.0 2.3e-07 30.5 5.5 2.2 2 1 1 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 EPE34890.1 - 4.4e-69 232.7 0.0 4.4e-69 232.7 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPE34890.1 - 4.2e-48 164.3 0.0 1.1e-47 162.9 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EPE34890.1 - 4.4e-36 123.3 0.7 1.4e-35 121.7 0.5 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EPE34890.1 - 3e-35 122.5 0.0 7.9e-35 121.1 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EPE34890.1 - 1.6e-19 69.9 4.5 4.8e-10 39.5 0.4 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EPE34890.1 - 4.9e-15 55.4 0.0 9.5e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 EPE34890.1 - 1.2e-07 31.5 2.1 0.023 14.4 0.0 4.2 3 1 1 4 4 4 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE34890.1 - 3.1e-05 23.9 1.4 0.0053 16.6 0.0 3.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 EPE34890.1 - 0.00041 19.4 0.1 0.0012 17.9 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ank_2 PF12796.2 EPE34891.1 - 8.9e-58 192.6 4.4 4.2e-11 43.0 0.0 13.7 7 4 6 13 13 13 11 Ankyrin repeats (3 copies) Ank PF00023.25 EPE34891.1 - 7.3e-20 69.7 26.5 0.012 15.3 0.0 17.9 21 0 0 21 21 21 7 Ankyrin repeat Ank_3 PF13606.1 EPE34891.1 - 1e-15 56.2 15.0 0.0035 17.4 0.0 17.2 16 2 2 18 18 18 1 Ankyrin repeat Ank_4 PF13637.1 EPE34891.1 - 1.1e-12 48.0 18.7 0.067 13.7 0.0 13.0 15 2 1 16 16 16 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE34891.1 - 1.1e-11 44.5 14.9 0.0053 16.9 0.0 13.3 13 2 3 16 16 16 1 Ankyrin repeats (many copies) Sds3 PF08598.6 EPE34893.1 - 1.6e-57 194.3 4.4 2.4e-57 193.7 3.1 1.4 1 0 0 1 1 1 1 Sds3-like PTCB-BRCT PF12738.2 EPE34895.1 - 0.00017 21.3 0.6 0.00063 19.5 0.1 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EPE34895.1 - 0.0011 19.0 0.0 0.0073 16.4 0.0 2.4 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain KilA-N PF04383.8 EPE34897.1 - 0.00034 20.2 0.0 0.0046 16.5 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain CcoS PF03597.10 EPE34898.1 - 0.74 9.3 3.9 1.5 8.3 2.7 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Aldedh PF00171.17 EPE34899.1 - 3e-08 32.4 8.5 0.0014 17.0 0.0 3.0 3 0 0 3 3 3 3 Aldehyde dehydrogenase family PCI PF01399.22 EPE34900.1 - 0.00082 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF3313 PF11769.3 EPE34900.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Rep_fac-A_C PF08646.5 EPE34901.1 - 5.6e-49 165.6 9.2 8.1e-49 165.0 2.3 2.6 2 1 0 2 2 2 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 EPE34901.1 - 1.3e-24 85.9 0.7 2.7e-24 84.8 0.0 1.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EPE34901.1 - 1.8e-14 53.3 2.0 4.8e-11 42.3 0.0 4.0 5 0 0 5 5 5 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 EPE34901.1 - 0.00088 19.3 0.0 0.007 16.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF223 DLH PF01738.13 EPE34902.1 - 8.8e-21 74.1 0.0 1.1e-19 70.5 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPE34902.1 - 6.5e-09 35.6 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE34902.1 - 0.0084 16.0 0.0 0.7 9.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE34902.1 - 0.013 15.0 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EPE34902.1 - 0.095 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Amido_AtzD_TrzD PF09663.5 EPE34905.1 - 2.2e-93 312.7 2.0 3.2e-93 312.2 1.4 1.2 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Glyco_hydro_10 PF00331.15 EPE34906.1 - 1.8e-94 316.3 0.0 2.2e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Potass_KdpF PF09604.5 EPE34906.1 - 0.3 10.9 1.3 0.83 9.5 0.9 1.7 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Tyrosinase PF00264.15 EPE34907.1 - 2.2e-30 106.4 3.3 3.1e-30 106.0 2.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase SCFA_trans PF02667.9 EPE34907.1 - 0.17 10.6 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Short chain fatty acid transporter Sugar_tr PF00083.19 EPE34908.1 - 1.1e-127 426.4 30.4 1.2e-127 426.2 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE34908.1 - 2.2e-20 72.7 38.0 1.2e-18 67.0 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Arteri_Gl PF00951.13 EPE34908.1 - 0.022 14.3 1.2 0.022 14.3 0.8 1.8 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein ABC2_membrane_5 PF13346.1 EPE34908.1 - 0.37 10.0 33.9 0.21 10.8 5.4 4.2 3 1 2 5 5 5 0 ABC-2 family transporter protein Amastin PF07344.6 EPE34909.1 - 3.1 7.3 11.5 0.28 10.7 0.2 3.5 3 1 1 4 4 4 0 Amastin surface glycoprotein E1-E2_ATPase PF00122.15 EPE34910.1 - 2.7e-66 222.8 1.1 2.7e-66 222.8 0.7 2.3 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EPE34910.1 - 1.5e-24 87.6 1.9 1.1e-23 84.7 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPE34910.1 - 6e-13 49.3 0.0 1.3e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPE34910.1 - 6.7e-10 38.2 0.0 1.7e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPE34910.1 - 0.0018 17.9 0.1 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FmdE PF02663.9 EPE34910.1 - 0.036 13.9 1.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Hydrolase_like2 PF13246.1 EPE34910.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit RINGv PF12906.2 EPE34911.1 - 0.011 15.7 11.1 0.023 14.7 7.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_2 PF13639.1 EPE34911.1 - 0.085 12.6 10.5 0.16 11.8 7.3 1.5 1 0 0 1 1 1 0 Ring finger domain DUF2688 PF10892.3 EPE34911.1 - 1.7 8.3 5.0 0.69 9.6 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Fungal_trans_2 PF11951.3 EPE34913.1 - 3.8e-08 32.3 0.0 6.4e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EPE34914.1 - 1.5e-33 116.0 0.0 2.1e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE34914.1 - 3.9e-13 49.7 0.0 5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE34914.1 - 1.3e-11 44.5 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPE34914.1 - 0.0023 16.8 0.0 0.0037 16.1 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Lin0512_fam PF09585.5 EPE34914.1 - 0.015 14.8 0.0 0.042 13.4 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) Eno-Rase_NADH_b PF12242.3 EPE34914.1 - 0.045 13.5 0.3 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sugar_tr PF00083.19 EPE34915.1 - 1.4e-89 300.7 30.8 1.8e-89 300.3 21.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE34915.1 - 7.3e-15 54.5 45.3 4e-11 42.2 23.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoIIIAC PF06686.6 EPE34915.1 - 3.5 7.5 5.3 2.4 8.0 0.0 2.8 3 0 0 3 3 3 0 Stage III sporulation protein AC/AD protein family HORMA PF02301.13 EPE34916.1 - 8.7e-26 90.6 0.0 1.1e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 HORMA domain CBS PF00571.23 EPE34916.1 - 0.097 12.4 0.1 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 CBS domain IBN_N PF03810.14 EPE34917.1 - 2.9e-09 36.7 0.0 3.3e-08 33.3 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EPE34917.1 - 3.4e-05 23.7 0.0 0.00075 19.4 0.0 2.8 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 EPE34917.1 - 0.0059 16.5 0.2 15 5.9 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat FAD_binding_4 PF01565.18 EPE34918.1 - 6.3e-25 87.2 1.1 1.1e-24 86.5 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE34918.1 - 6e-11 42.0 0.3 1.4e-10 40.9 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.6 EPE34919.1 - 2.2e-29 102.3 0.7 3.9e-29 101.5 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ras PF00071.17 EPE34921.1 - 3.4e-59 198.8 0.2 4.1e-59 198.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE34921.1 - 6.2e-19 68.6 0.0 8.8e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE34921.1 - 1.8e-08 33.7 0.0 2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPE34921.1 - 1.5e-07 31.0 0.1 6.7e-07 28.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPE34921.1 - 0.0029 17.5 0.0 0.005 16.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE34921.1 - 0.0036 16.6 0.0 0.0057 15.9 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EPE34921.1 - 0.038 13.1 0.1 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EPE34921.1 - 0.057 12.6 0.1 0.12 11.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MoCF_biosynth PF00994.19 EPE34922.1 - 4.4e-29 100.7 0.0 6.9e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain CRAL_TRIO PF00650.15 EPE34923.1 - 4e-26 91.4 0.0 5.6e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPE34923.1 - 7.5e-10 38.7 0.1 2.3e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Phage_Nu1 PF07471.7 EPE34923.1 - 0.04 13.3 0.2 0.076 12.4 0.1 1.4 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Glyco_hydro_61 PF03443.9 EPE34924.1 - 1.5e-26 93.5 0.0 2.3e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PapG_N PF03627.8 EPE34924.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 PapG carbohydrate binding domain Ion_trans PF00520.26 EPE34925.1 - 5.2e-07 29.1 21.9 1.9e-06 27.2 11.5 2.8 2 1 0 2 2 2 2 Ion transport protein PI31_Prot_N PF11566.3 EPE34926.1 - 5.4e-35 120.2 0.0 6.6e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EPE34926.1 - 1.5e-15 57.6 22.2 1.5e-15 57.6 15.4 2.4 3 1 0 3 3 3 1 PI31 proteasome regulator IBR PF01485.16 EPE34927.1 - 0.0029 17.4 9.8 0.0029 17.4 6.8 3.3 2 1 1 3 3 3 2 IBR domain Acetyltransf_7 PF13508.1 EPE34928.1 - 0.00016 21.7 0.0 0.00051 20.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE34928.1 - 0.003 17.4 0.0 0.0066 16.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE34928.1 - 0.08 12.9 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF2036 PF09724.4 EPE34929.1 - 0.00017 20.8 0.0 0.00021 20.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) RhoGEF PF00621.15 EPE34930.1 - 8.4e-24 84.4 0.1 6.1e-23 81.6 0.0 2.4 3 0 0 3 3 3 1 RhoGEF domain DUF3507 PF12015.3 EPE34930.1 - 0.00082 18.9 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Flagellin_N PF00669.15 EPE34930.1 - 0.015 15.0 1.6 0.67 9.7 0.2 2.9 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region ATG16 PF08614.6 EPE34930.1 - 3.7 7.3 14.8 0.47 10.2 5.6 2.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Thiolase_C PF02803.13 EPE34931.1 - 0.062 12.7 0.1 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 Thiolase, C-terminal domain Glyco_hydro_15 PF00723.16 EPE34932.1 - 6e-87 292.0 0.0 7.1e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EPE34932.1 - 4.4e-22 77.4 0.0 1.1e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain CENP-M PF11111.3 EPE34933.1 - 0.0026 17.0 0.1 0.0053 16.0 0.1 1.4 1 0 0 1 1 1 1 Centromere protein M (CENP-M) Spt4 PF06093.8 EPE34934.1 - 0.0026 17.5 4.2 0.0054 16.5 2.9 1.5 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Zn_clus PF00172.13 EPE34934.1 - 0.0055 16.5 5.6 0.011 15.6 3.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1290 PF06947.7 EPE34934.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) MOSC_N PF03476.11 EPE34935.1 - 6.5e-16 58.1 0.0 1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EPE34935.1 - 1.6e-12 47.0 0.0 2.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 MOSC domain p450 PF00067.17 EPE34936.1 - 1.5e-68 231.4 0.0 1.9e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.7 EPE34937.1 - 3.9e-06 27.2 0.0 5.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE34937.1 - 1.4e-05 24.6 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE34937.1 - 0.00013 22.2 0.0 0.00018 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE34937.1 - 0.0071 16.8 0.0 0.0098 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain His_Phos_1 PF00300.17 EPE34938.1 - 3.9e-17 62.7 0.0 6e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CsbD PF05532.7 EPE34939.1 - 4.6e-06 26.2 9.2 0.0023 17.5 1.1 2.2 2 0 0 2 2 2 2 CsbD-like DUF3632 PF12311.3 EPE34941.1 - 2.7e-14 53.3 0.0 4.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) VCBS PF13517.1 EPE34944.1 - 1.6e-29 102.0 62.3 4.9e-13 49.2 2.7 9.0 6 2 4 10 10 10 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EPE34944.1 - 4.3e-15 54.9 40.0 0.0012 18.4 0.0 9.3 9 0 0 9 9 9 6 FG-GAP repeat Lipase_GDSL_2 PF13472.1 EPE34944.1 - 8.8e-11 42.2 0.0 2e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE34944.1 - 1e-08 35.2 1.2 2.9e-08 33.8 0.9 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.3 EPE34944.1 - 7.1e-05 22.3 13.8 1.3 8.3 0.0 6.3 5 2 2 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 EPE34944.1 - 0.00036 20.3 0.0 0.00057 19.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Mito_fiss_reg PF05308.6 EPE34944.1 - 0.77 9.0 5.4 1.2 8.4 3.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator SBDS PF01172.13 EPE34945.1 - 1.3e-20 73.0 0.7 1.5e-20 72.7 0.5 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Clr2 PF10383.4 EPE34946.1 - 3.7e-23 82.0 0.0 7.7e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 SNF2_N PF00176.18 EPE34947.1 - 1.6e-62 210.9 0.1 9.8e-62 208.4 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE34947.1 - 1.4e-09 37.6 0.1 9.6e-09 34.9 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EPE34947.1 - 1.4e-08 33.9 0.1 1e-06 27.7 0.1 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 EPE34947.1 - 7.7e-05 22.3 23.1 0.00059 19.4 9.0 3.3 2 1 1 3 3 3 2 PHD-finger ResIII PF04851.10 EPE34947.1 - 0.044 13.6 0.0 0.25 11.1 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit C1_1 PF00130.17 EPE34947.1 - 1.3 8.8 23.6 1.9 8.2 5.2 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GDA1_CD39 PF01150.12 EPE34948.1 - 6.3e-101 337.9 0.0 9.2e-101 337.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PPV_E2_C PF00511.12 EPE34948.1 - 0.05 13.5 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 E2 (early) protein, C terminal DYW_deaminase PF14432.1 EPE34949.1 - 7.9e-18 64.5 0.5 2.3e-17 63.0 0.4 1.7 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases Ank_2 PF12796.2 EPE34949.1 - 9.4e-14 51.5 0.0 2.5e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE34949.1 - 2.5e-13 49.1 0.0 1.9e-07 30.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EPE34949.1 - 3.1e-07 30.7 0.9 1.1e-05 25.7 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE34949.1 - 1.5e-06 28.2 0.1 0.00026 21.1 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE34949.1 - 3e-06 26.9 0.0 0.077 13.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Asp PF00026.18 EPE34950.1 - 2.7e-17 62.9 4.5 3.8e-17 62.5 3.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TMEM51 PF15345.1 EPE34950.1 - 0.0052 16.5 0.1 0.0052 16.5 0.0 1.9 2 0 0 2 2 1 1 Transmembrane protein 51 SKG6 PF08693.5 EPE34950.1 - 0.0084 15.4 1.5 0.02 14.2 1.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EPE34950.1 - 0.021 13.1 0.0 0.033 12.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Glycophorin_A PF01102.13 EPE34950.1 - 0.027 14.2 0.0 0.027 14.2 0.0 2.2 2 0 0 2 2 1 0 Glycophorin A VSP PF03302.8 EPE34950.1 - 0.052 12.1 0.0 0.079 11.5 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.10 EPE34950.1 - 0.065 12.7 0.4 0.15 11.6 0.3 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EPE34950.1 - 0.072 13.4 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain STE2 PF02116.10 EPE34950.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR Syndecan PF01034.15 EPE34950.1 - 0.12 12.0 0.2 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain IncA PF04156.9 EPE34950.1 - 0.31 10.6 0.0 0.5 9.9 0.0 1.3 1 0 0 1 1 1 0 IncA protein F-box PF00646.28 EPE34952.1 - 3.2e-09 36.2 0.0 6.4e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE34952.1 - 3.3e-09 36.3 0.2 6.4e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 F-box-like DUF775 PF05603.7 EPE34953.1 - 4.2e-54 183.1 0.0 4.7e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 EPE34954.1 - 1e-06 28.4 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.10 EPE34955.1 - 1.7e-36 125.4 0.0 1.9e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 EPE34956.1 - 1.6e-104 349.6 0.0 3e-104 348.7 0.0 1.4 1 1 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 EPE34957.1 - 1e-13 50.8 0.0 2e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PROL5-SMR PF15621.1 EPE34961.1 - 0.96 9.9 5.8 9.5 6.6 1.0 3.0 2 1 1 3 3 3 0 Proline-rich submaxillary gland androgen-regulated family RNase_PH PF01138.16 EPE34962.1 - 3.2e-26 92.1 0.0 7e-26 91.1 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Anp1 PF03452.9 EPE34963.1 - 2e-120 401.0 0.3 2.5e-119 397.4 0.0 2.0 2 0 0 2 2 2 1 Anp1 Glyco_transf_7N PF13733.1 EPE34963.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 DUF334 PF03904.8 EPE34963.1 - 0.67 9.2 6.4 1.1 8.4 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Sec7 PF01369.15 EPE34964.1 - 5.2e-61 205.6 0.3 9.5e-61 204.7 0.2 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EPE34964.1 - 3e-18 65.8 0.1 7.5e-12 45.0 0.0 3.4 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4360 PF14273.1 EPE34965.1 - 6.5e-22 78.0 0.0 7.9e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RRM_1 PF00076.17 EPE34966.1 - 8.3e-26 89.4 1.2 1.5e-12 46.9 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE34966.1 - 1.3e-16 60.3 0.1 2.1e-07 30.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE34966.1 - 5e-16 58.2 0.0 1.2e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EPE34966.1 - 0.00049 19.7 0.5 0.0008 19.0 0.3 1.5 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 EPE34966.1 - 0.0028 17.3 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 DUF45 PF01863.12 EPE34966.1 - 0.2 11.4 1.3 0.27 11.0 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF45 ATP-synt_D PF01813.12 EPE34967.1 - 1.3e-66 223.8 1.8 1.6e-66 223.6 1.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Mig-14 PF07395.6 EPE34967.1 - 0.27 10.2 2.1 0.76 8.7 0.1 2.0 2 0 0 2 2 2 0 Mig-14 SYCE1 PF15233.1 EPE34967.1 - 0.45 10.4 9.0 0.22 11.4 3.4 2.2 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Nup54 PF13874.1 EPE34967.1 - 0.91 9.1 6.9 2.8 7.5 0.2 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Viral_P18 PF04521.8 EPE34967.1 - 2.3 7.6 5.4 4.1 6.8 0.1 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Ribosomal_L6e PF01159.14 EPE34967.1 - 3.1 8.0 7.2 6.8 6.9 4.4 2.1 1 1 1 2 2 2 0 Ribosomal protein L6e TPR_14 PF13428.1 EPE34968.1 - 3.3e-12 45.8 7.0 1.5 9.6 0.0 9.8 8 2 1 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPE34968.1 - 4.4e-11 42.5 0.7 0.85 9.5 0.0 7.3 7 1 1 8 8 8 2 Tetratricopeptide repeat Suf PF05843.9 EPE34968.1 - 3.8e-08 33.4 9.5 0.61 9.7 1.1 5.5 5 0 0 5 5 5 3 Suppressor of forked protein (Suf) TPR_15 PF13429.1 EPE34968.1 - 1.8e-07 30.5 4.0 0.00011 21.3 0.6 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPE34968.1 - 3.2e-07 29.8 5.1 0.17 11.5 0.0 7.1 9 0 0 9 9 7 1 TPR repeat SNAP PF14938.1 EPE34968.1 - 4.3e-05 22.8 1.7 0.8 8.7 0.1 4.8 5 1 1 6 6 6 2 Soluble NSF attachment protein, SNAP Mad3_BUB1_I PF08311.7 EPE34968.1 - 5.3e-05 23.0 11.0 0.5 10.1 0.1 6.6 5 2 0 6 6 6 1 Mad3/BUB1 homology region 1 RPN7 PF10602.4 EPE34968.1 - 7.7e-05 22.1 0.2 0.00053 19.4 0.2 2.5 2 1 0 2 2 2 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 EPE34968.1 - 0.00018 21.8 4.4 3.5 8.0 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPE34968.1 - 0.0033 17.2 17.0 5.5 7.1 0.1 7.3 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPE34968.1 - 0.0056 16.3 6.5 0.55 10.1 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EPE34968.1 - 0.091 12.0 0.0 10 5.4 0.0 3.0 3 0 0 3 3 3 0 SHNi-TPR PPR_3 PF13812.1 EPE34968.1 - 0.11 12.8 0.0 3.9 7.9 0.0 3.8 4 0 0 4 4 2 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 EPE34968.1 - 0.11 12.9 5.3 4.7 7.8 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPE34968.1 - 5.4 7.4 6.4 7.7 7.0 0.0 4.9 8 0 0 8 8 6 0 Tetratricopeptide repeat Zn_clus PF00172.13 EPE34970.1 - 3.7e-08 33.1 9.2 3.7e-08 33.1 6.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuclease_3 PF00636.21 EPE34971.1 - 1.8e-41 141.1 0.0 1.6e-19 70.4 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EPE34971.1 - 5.1e-22 78.1 0.0 5e-10 39.4 0.0 4.0 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EPE34971.1 - 1.2e-20 73.0 0.0 9.9e-19 66.9 0.0 2.9 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 EPE34971.1 - 7.7e-15 54.5 0.1 2e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE34971.1 - 6.1e-13 49.0 0.1 1.6e-12 47.6 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPE34971.1 - 7.8e-12 45.0 0.0 2e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 EPE34971.1 - 0.0029 18.1 0.1 5.4 7.6 0.1 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif DUF2075 PF09848.4 EPE34971.1 - 0.031 13.2 0.0 0.083 11.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EPE34971.1 - 0.12 12.4 0.1 0.76 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain TAP42 PF04177.7 EPE34972.1 - 3.4e-101 338.5 0.9 3.9e-101 338.4 0.6 1.0 1 0 0 1 1 1 1 TAP42-like family Herpes_capsid PF06112.6 EPE34974.1 - 2.6 8.0 18.3 12 5.9 12.7 1.9 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein Fig1 PF12351.3 EPE34976.1 - 6.1e-18 65.3 2.7 1e-17 64.5 1.9 1.3 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 EI24 PF07264.6 EPE34976.1 - 0.00049 19.6 0.4 0.0045 16.4 0.1 2.2 2 1 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) SUR7 PF06687.7 EPE34976.1 - 0.0063 16.0 6.8 0.014 15.0 4.7 1.5 1 1 0 1 1 1 1 SUR7/PalI family MscS_TM PF12794.2 EPE34976.1 - 0.022 13.3 0.6 0.022 13.3 0.4 2.1 2 1 1 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 Cation_ATPase_C PF00689.16 EPE34976.1 - 0.12 11.8 3.6 0.072 12.6 1.1 1.7 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF998 PF06197.8 EPE34976.1 - 0.29 10.4 5.3 0.08 12.2 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF998) RDD PF06271.7 EPE34976.1 - 0.76 9.6 5.4 7.5 6.4 0.0 2.8 3 0 0 3 3 3 0 RDD family Grp1_Fun34_YaaH PF01184.14 EPE34976.1 - 0.79 8.9 5.8 0.32 10.2 0.6 2.1 1 1 1 2 2 2 0 GPR1/FUN34/yaaH family Peptidase_M1 PF01433.15 EPE34977.1 - 7.2e-130 433.5 0.1 1.2e-129 432.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EPE34977.1 - 4.1e-75 253.0 0.5 8.3e-75 252.0 0.1 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EPE34977.1 - 4.8e-23 81.5 1.8 1.3e-22 80.2 0.5 2.2 2 0 0 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 EPE34977.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 CBFD_NFYB_HMF PF00808.18 EPE34978.1 - 3e-06 27.1 0.1 3.8e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1980 PF09323.5 EPE34978.1 - 0.094 12.4 0.1 0.1 12.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SRR1 PF07985.7 EPE34980.1 - 4e-09 36.2 0.1 7.2e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 SRR1 PIR PF00399.14 EPE34981.1 - 3.3e-31 105.5 70.8 2.5e-07 29.8 2.9 7.3 6 1 1 7 7 7 6 Yeast PIR protein repeat Glyco_hydro_17 PF00332.13 EPE34982.1 - 1.2e-08 34.3 1.5 3.2e-05 23.1 0.4 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Prion PF00377.13 EPE34982.1 - 0.09 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain Pro-kuma_activ PF09286.6 EPE34985.1 - 5.3e-31 107.5 0.2 3.2e-30 105.0 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EPE34985.1 - 1.9e-07 30.5 3.4 3.1e-07 29.8 2.3 1.3 1 0 0 1 1 1 1 Subtilase family TMEM154 PF15102.1 EPE34986.1 - 0.041 13.5 1.5 0.061 13.0 1.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF1049 PF06305.6 EPE34986.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Glyco_hydro_43 PF04616.9 EPE34989.1 - 2e-73 246.9 0.9 2.6e-73 246.6 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF3628 PF12300.3 EPE34991.1 - 3.2 7.7 8.5 22 5.0 4.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3628) MFS_1 PF07690.11 EPE34994.1 - 6e-35 120.5 32.5 9.9e-35 119.8 22.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 EPE34995.1 - 3.8e-13 49.8 0.0 6.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE34995.1 - 2.7e-06 27.1 0.0 4.4e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE34995.1 - 5.3e-05 22.8 0.0 7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE34995.1 - 0.01 15.0 0.3 0.076 12.2 0.1 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family FAD_binding_3 PF01494.14 EPE34996.1 - 9.8e-16 57.7 0.8 6e-13 48.5 0.5 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EPE34996.1 - 0.00047 20.1 0.0 0.0033 17.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2OG-FeII_Oxy_2 PF13532.1 EPE34997.1 - 5.6e-26 91.5 0.0 1.3e-25 90.4 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3716 PF12511.3 EPE34998.1 - 8.5e-14 50.9 6.4 1.3e-13 50.2 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Fungal_trans_2 PF11951.3 EPE34999.1 - 1e-07 30.9 0.4 1.9e-07 30.0 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE34999.1 - 0.00013 21.8 5.3 0.00036 20.3 3.7 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BACK PF07707.10 EPE35000.1 - 0.066 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch Alginate_lyase2 PF08787.6 EPE35001.1 - 6.3e-50 170.0 0.0 7.2e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase FixQ PF05545.6 EPE35002.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Ank_2 PF12796.2 EPE35003.1 - 2.1e-47 159.3 1.4 1.1e-14 54.5 0.0 7.7 2 2 7 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 EPE35003.1 - 7.3e-36 120.2 12.3 9.4e-07 28.3 0.1 13.5 14 0 0 14 14 14 8 Ankyrin repeat Ank_3 PF13606.1 EPE35003.1 - 3.9e-34 113.2 8.3 0.00048 20.1 0.0 14.2 15 0 0 15 15 15 6 Ankyrin repeat Ank_4 PF13637.1 EPE35003.1 - 1.8e-31 107.9 3.6 1.7e-08 34.7 0.0 9.6 7 2 3 10 10 10 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE35003.1 - 5.5e-21 74.1 5.6 0.0039 17.4 0.1 8.2 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Clr5 PF14420.1 EPE35003.1 - 1.2e-14 53.8 1.1 2.8e-14 52.7 0.8 1.6 1 0 0 1 1 1 1 Clr5 domain Gly_transf_sug PF04488.10 EPE35004.1 - 2.4e-14 53.5 0.0 4.2e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Pkinase PF00069.20 EPE35005.1 - 9e-62 208.5 0.0 1.3e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE35005.1 - 2e-29 102.4 0.0 3.2e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE35005.1 - 4.6e-05 22.5 0.0 8.5e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPE35005.1 - 0.00039 20.2 0.1 0.0061 16.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Phage_int_SAM_1 PF02899.12 EPE35005.1 - 0.051 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Baculo_PEP_C PF04513.7 EPE35006.1 - 0.4 10.5 6.9 12 5.7 1.1 3.7 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin PF00261.15 EPE35006.1 - 10 5.1 47.9 1.3 8.0 0.7 3.4 3 1 0 3 3 3 0 Tropomyosin DUF4336 PF14234.1 EPE35007.1 - 3e-17 62.7 0.6 4.4e-14 52.3 0.2 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) IMS PF00817.15 EPE35009.1 - 7.6e-34 116.6 0.0 1.4e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EPE35009.1 - 2.2e-14 53.5 0.0 4.3e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EPE35009.1 - 1.2e-05 25.0 0.0 4e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif DUF3656 PF12392.3 EPE35011.1 - 0.096 12.7 0.2 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Collagenase zf-DHHC PF01529.15 EPE35012.1 - 4.3e-30 104.3 0.3 4.3e-30 104.3 0.2 2.5 3 0 0 3 3 3 1 DHHC palmitoyltransferase COX4_pro_2 PF07835.7 EPE35012.1 - 0.022 14.7 0.5 0.022 14.7 0.4 1.9 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV peroxidase PF00141.18 EPE35013.1 - 1.3e-15 57.4 0.0 2.7e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Peroxidase Exo_endo_phos PF03372.18 EPE35014.1 - 2.9e-18 66.7 0.0 3.9e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PI3Ka PF00613.15 EPE35015.1 - 1e-54 184.5 0.1 1.9e-54 183.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EPE35015.1 - 3.6e-43 147.7 0.0 2.9e-42 144.7 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EPE35015.1 - 4.1e-33 114.1 0.0 6.8e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.5 EPE35016.1 - 6.2e-34 115.8 0.0 1.7e-33 114.5 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EPE35016.1 - 3.3e-14 52.4 0.2 9.7e-14 50.9 0.1 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE FSH1 PF03959.8 EPE35017.1 - 2.1e-53 180.9 0.0 2.7e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EPE35017.1 - 2e-05 24.5 0.2 0.042 13.7 0.0 2.4 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE35017.1 - 4.4e-05 23.2 0.0 0.00014 21.6 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 EPE35017.1 - 0.0003 20.1 0.0 0.00056 19.2 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 EPE35017.1 - 0.0079 15.9 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EPE35017.1 - 0.084 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Thioesterase PF00975.15 EPE35017.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S15 PF02129.13 EPE35017.1 - 0.16 11.3 0.0 6.3 6.1 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) HsbA PF12296.3 EPE35018.1 - 1.6e-14 53.8 0.4 2.2e-14 53.3 0.2 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.7 EPE35018.1 - 0.34 10.7 2.6 0.96 9.2 1.8 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus APH PF01636.18 EPE35019.1 - 7.2e-12 45.5 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE35019.1 - 3.7e-05 23.3 0.0 5.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPE35019.1 - 0.055 12.5 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 EPE35019.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Parvo_coat PF00740.13 EPE35020.1 - 0.096 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 RabGAP-TBC PF00566.13 EPE35021.1 - 4.8e-47 160.1 0.0 7e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EPE35021.1 - 2.7e-06 27.4 0.5 2.6e-05 24.2 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EPE35021.1 - 4.1e-05 23.1 0.8 0.0089 15.8 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 EPE35021.1 - 0.0004 19.4 0.1 0.079 12.3 0.2 3.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EPE35021.1 - 0.015 14.6 0.9 0.058 12.7 0.6 2.0 1 0 0 1 1 1 0 EF hand GRAM PF02893.15 EPE35021.1 - 0.044 13.3 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 GRAM domain PTR2 PF00854.16 EPE35022.1 - 5.6e-32 110.9 9.9 3.7e-18 65.4 1.2 2.4 1 1 0 2 2 2 2 POT family TMEM223 PF14640.1 EPE35023.1 - 0.054 13.4 0.0 0.073 12.9 0.0 1.3 1 1 0 1 1 1 0 Transmembrane protein 223 Sulfatase PF00884.18 EPE35025.1 - 1.6e-63 214.7 0.1 2.4e-63 214.2 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EPE35025.1 - 0.0042 16.4 5.3 0.0072 15.6 1.9 2.2 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1620 PF07774.8 EPE35026.1 - 2.2e-68 229.7 0.0 3.7e-68 229.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ PF01011.16 EPE35026.1 - 1.1e-06 27.9 1.1 0.018 14.5 0.0 4.4 4 0 0 4 4 4 2 PQQ enzyme repeat adh_short_C2 PF13561.1 EPE35027.1 - 3.7e-22 79.2 0.0 4.5e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE35027.1 - 2e-12 47.3 0.0 2.7e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE35027.1 - 0.00043 19.9 0.2 0.00096 18.8 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EPE35027.1 - 0.019 14.9 0.2 0.047 13.7 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EPE35027.1 - 0.023 14.4 0.1 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Acetate_kinase PF00871.12 EPE35027.1 - 0.023 13.2 0.0 0.032 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetokinase family THF_DHG_CYH_C PF02882.14 EPE35027.1 - 0.028 13.4 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Helicase_RecD PF05127.9 EPE35027.1 - 0.046 13.3 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase NAD_binding_7 PF13241.1 EPE35027.1 - 0.053 13.7 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF1989 PF09347.5 EPE35028.1 - 1.2e-48 164.6 0.0 1.4e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) RTC PF01137.16 EPE35030.1 - 5.6e-42 143.0 0.0 1e-41 142.2 0.0 1.4 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EPE35030.1 - 0.0045 16.9 0.0 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF3129 PF11327.3 EPE35031.1 - 5.1e-57 192.6 15.4 6.2e-57 192.3 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Glyoxalase_2 PF12681.2 EPE35032.1 - 6.1e-09 36.4 0.0 8.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EPE35032.1 - 2.7e-07 30.5 0.0 4.4e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EPE35032.1 - 0.002 18.0 0.0 0.0098 15.8 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EPE35032.1 - 0.0084 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ThiF PF00899.16 EPE35033.1 - 7.6e-36 122.9 0.0 1.2e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 EPE35033.1 - 0.0059 16.5 0.9 0.017 15.0 0.0 2.2 3 0 0 3 3 3 1 TrkA-N domain ApbA PF02558.11 EPE35033.1 - 0.013 14.9 0.2 0.042 13.3 0.2 1.8 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 EPE35033.1 - 0.031 13.1 0.1 0.065 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glyco_hydro_17 PF00332.13 EPE35033.1 - 0.048 12.6 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 UDPG_MGDP_dh_N PF03721.9 EPE35033.1 - 0.057 12.7 0.2 0.19 11.0 0.1 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EPE35033.1 - 0.081 12.5 0.2 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EPE35033.1 - 0.097 11.6 0.1 0.21 10.5 0.1 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase DUF3505 PF12013.3 EPE35034.1 - 4.3e-21 75.2 0.5 8.1e-21 74.3 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Fungal_trans_2 PF11951.3 EPE35034.1 - 4.5e-10 38.6 0.7 1.3e-09 37.1 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 EPE35035.1 - 8.2e-14 51.8 0.0 1.2e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE35035.1 - 1.7e-07 31.0 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 KR domain HET PF06985.6 EPE35036.1 - 1.8e-35 122.0 0.7 3.7e-35 121.0 0.2 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF2013 PF09431.5 EPE35036.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) CorA PF01544.13 EPE35037.1 - 0.0035 16.4 0.0 0.0065 15.5 0.0 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Methyltransf_23 PF13489.1 EPE35040.1 - 2.7e-26 92.2 0.0 4.9e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE35040.1 - 7.3e-14 52.0 0.0 1.7e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE35040.1 - 1.7e-11 43.9 0.0 3.4e-10 39.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE35040.1 - 5.3e-11 42.8 0.0 5.5e-10 39.6 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE35040.1 - 6.9e-10 39.4 0.0 8.5e-09 35.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE35040.1 - 8.1e-06 26.1 0.0 2.3e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE35040.1 - 7.2e-05 22.0 0.0 0.0089 15.1 0.0 2.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EPE35040.1 - 0.00012 21.2 0.0 0.00046 19.3 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EPE35040.1 - 0.00029 20.0 0.0 0.00065 18.8 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EPE35040.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EPE35040.1 - 0.0013 17.9 0.0 0.0053 15.9 0.0 1.9 2 1 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EPE35040.1 - 0.0043 17.0 0.0 0.018 15.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EPE35040.1 - 0.0095 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EPE35040.1 - 0.012 15.0 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 EPE35041.1 - 3.3e-33 114.8 0.0 4.9e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EPE35041.1 - 0.00013 22.4 0.0 0.00031 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF2805 PF10985.3 EPE35041.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) AMP-binding PF00501.23 EPE35042.1 - 8.4e-84 281.3 0.0 1e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE35042.1 - 5.8e-06 27.1 0.5 2.9e-05 24.9 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4070 PF13282.1 EPE35042.1 - 0.21 11.0 0.0 4.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) Asp PF00026.18 EPE35043.1 - 9.9e-68 228.7 15.4 1.2e-67 228.4 10.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPE35043.1 - 1.6e-08 34.6 2.3 1.1e-07 31.8 0.2 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EPE35043.1 - 4e-07 30.4 3.9 6.8e-05 23.2 0.6 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EPE35043.1 - 0.002 17.7 0.0 0.01 15.3 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal ATP-synt_C PF00137.16 EPE35044.1 - 2.8e-25 87.9 30.2 7.5e-14 51.3 6.2 2.0 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.17 EPE35045.1 - 8.1e-84 281.2 0.0 4.3e-83 278.8 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EPE35045.1 - 9.9e-46 155.0 0.0 1.9e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EPE35045.1 - 4.8e-36 124.3 0.0 8.1e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EPE35045.1 - 8.4e-14 51.0 0.0 1.6e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PAP2_3 PF14378.1 EPE35045.1 - 0.45 10.0 0.0 0.92 9.0 0.0 1.4 1 0 0 1 1 1 0 PAP2 superfamily Glypican PF01153.14 EPE35046.1 - 0.048 12.2 3.3 0.056 12.0 2.3 1.1 1 0 0 1 1 1 0 Glypican PapD_C PF02753.12 EPE35046.1 - 0.1 12.4 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Pili assembly chaperone PapD, C-terminal domain PGA2 PF07543.7 EPE35046.1 - 3.3 7.4 12.7 0.45 10.3 5.8 1.7 1 1 0 1 1 1 0 Protein trafficking PGA2 Amidase PF01425.16 EPE35047.1 - 5.4e-96 322.1 0.0 3.3e-95 319.5 0.0 1.9 1 1 0 1 1 1 1 Amidase Autophagy_N PF03986.8 EPE35048.1 - 1.3e-43 148.2 0.1 1.3e-43 148.2 0.0 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EPE35048.1 - 4.3e-22 78.0 0.5 7.5e-22 77.2 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EPE35048.1 - 5.1e-15 54.2 0.9 9.4e-15 53.4 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF2052 PF09747.4 EPE35049.1 - 2.5e-36 125.3 7.2 2.9e-36 125.0 5.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Herpes_UL56 PF04534.7 EPE35049.1 - 0.045 13.4 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein Y_phosphatase3 PF13350.1 EPE35050.1 - 4.4e-49 166.8 0.0 7e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EPE35050.1 - 3.6e-05 23.7 0.0 0.00011 22.2 0.0 1.8 1 1 1 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EPE35050.1 - 6.9e-05 22.3 0.0 0.00013 21.4 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EPE35050.1 - 0.0044 16.4 0.1 0.01 15.2 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.9 EPE35050.1 - 0.066 11.9 0.0 0.24 10.1 0.0 1.7 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain DSPc PF00782.15 EPE35050.1 - 0.13 11.8 0.0 0.4 10.2 0.0 1.9 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Bot1p PF12298.3 EPE35051.1 - 9.1e-50 168.9 3.7 5.1e-49 166.5 2.6 2.1 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Flavodoxin_3 PF12641.2 EPE35051.1 - 0.04 13.3 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain CBFD_NFYB_HMF PF00808.18 EPE35052.1 - 6.1e-17 61.4 1.0 1.3e-16 60.3 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPE35052.1 - 4.4e-05 23.5 0.0 0.00012 22.1 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Metallophos PF00149.23 EPE35053.1 - 1.2e-06 28.0 1.0 2.5e-06 27.0 0.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PRP38 PF03371.10 EPE35054.1 - 6.6e-62 208.1 0.0 7.9e-62 207.9 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Cu-oxidase_2 PF07731.9 EPE35055.1 - 6.8e-31 106.6 2.2 3e-29 101.3 0.3 2.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EPE35055.1 - 7.7e-21 74.0 2.0 7e-16 58.0 0.0 3.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EPE35055.1 - 0.00013 21.9 0.3 0.43 10.4 0.0 3.5 2 2 0 2 2 2 2 Multicopper oxidase Fungal_trans_2 PF11951.3 EPE35056.1 - 3.3e-07 29.2 3.8 5e-07 28.6 0.9 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE35056.1 - 3.3e-06 26.9 12.8 5.1e-06 26.2 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_12 PF08242.7 EPE35058.1 - 1.5e-12 47.8 0.0 2.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE35058.1 - 1.6e-12 47.4 0.0 2.2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE35058.1 - 6.2e-11 42.1 0.0 7.5e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE35058.1 - 6.5e-11 42.4 0.0 9.9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE35058.1 - 2.7e-10 40.8 0.0 3.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE35058.1 - 4e-09 36.8 0.0 6.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE35058.1 - 0.001 19.1 0.0 0.002 18.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EPE35058.1 - 0.0032 16.7 0.0 0.0043 16.3 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.9 EPE35058.1 - 0.011 15.1 0.0 0.057 12.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EPE35058.1 - 0.026 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EPE35058.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EPE35058.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.21 EPE35060.1 - 3.2e-13 49.3 0.0 6.3e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE35060.1 - 0.0013 18.4 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Transket_pyr PF02779.19 EPE35061.1 - 9.7e-47 158.7 0.0 1.3e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EPE35061.1 - 8.2e-35 119.4 0.2 2.1e-34 118.1 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Aminotran_5 PF00266.14 EPE35061.1 - 0.093 11.4 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V 2OG-FeII_Oxy_3 PF13640.1 EPE35062.1 - 2.4e-06 27.9 0.0 3.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPE35062.1 - 0.00014 22.1 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CTV_P6 PF06706.6 EPE35062.1 - 0.014 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein Thioredoxin_6 PF13848.1 EPE35063.1 - 3.6e-17 62.7 0.0 1.1e-12 48.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 EPE35063.1 - 1.1e-08 34.6 0.0 8.7e-07 28.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin zf-C2H2_jaz PF12171.3 EPE35064.1 - 1.7e-06 27.9 3.0 3.1e-06 27.1 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPE35064.1 - 0.00079 19.5 0.5 0.0016 18.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EPE35064.1 - 0.011 16.0 0.1 0.021 15.1 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.7 EPE35064.1 - 0.021 14.4 1.9 0.035 13.7 1.3 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2 PF00096.21 EPE35064.1 - 0.064 13.6 0.4 0.12 12.8 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EPE35064.1 - 0.066 13.3 0.2 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Bindin PF02084.10 EPE35064.1 - 0.14 12.1 1.9 0.18 11.8 1.4 1.2 1 0 0 1 1 1 0 Bindin Vps54 PF07928.7 EPE35065.1 - 2.7e-42 144.1 0.0 6.8e-42 142.8 0.0 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EPE35065.1 - 3.9e-07 29.2 2.2 5.2e-07 28.8 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 EPE35065.1 - 0.024 14.2 0.2 1.4 8.5 0.1 2.9 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain LUC7 PF03194.10 EPE35065.1 - 0.038 13.5 1.3 0.066 12.7 0.3 1.8 2 0 0 2 2 2 0 LUC7 N_terminus Chorion_S16 PF05836.7 EPE35065.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Chorion protein S16 DUF904 PF06005.7 EPE35065.1 - 2.6 8.4 6.0 0.48 10.7 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF904) SnoaL_4 PF13577.1 EPE35066.1 - 3.5e-16 59.2 0.0 4e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Zn_clus PF00172.13 EPE35067.1 - 0.0011 18.8 12.1 0.0018 18.1 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrpF PF04303.8 EPE35068.1 - 8.3e-67 225.5 0.0 1.1e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 PrpF protein HET PF06985.6 EPE35069.1 - 3.4e-25 88.8 0.0 6e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lipase_GDSL_2 PF13472.1 EPE35070.1 - 1.5e-12 48.0 0.0 3e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3835 PF12927.2 EPE35070.1 - 0.049 14.6 0.5 0.11 13.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) TT_ORF2a PF08197.6 EPE35070.1 - 0.2 11.4 5.7 6 6.7 0.5 2.7 2 0 0 2 2 2 0 pORF2a truncated protein Gly_transf_sug PF04488.10 EPE35072.1 - 1.5e-06 28.5 0.0 3.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EPE35072.1 - 0.00051 19.2 0.0 0.00074 18.7 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EPE35072.1 - 0.0093 14.4 0.1 0.043 12.3 0.0 1.8 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Ferric_reduct PF01794.14 EPE35073.1 - 5.5e-21 74.9 14.8 1.4e-20 73.6 10.3 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EPE35073.1 - 3.6e-05 23.5 0.0 0.0014 18.4 0.0 2.5 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EPE35073.1 - 0.00072 19.4 3.1 0.039 13.8 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain CFEM PF05730.6 EPE35073.1 - 0.0025 17.6 2.6 0.0044 16.7 1.8 1.3 1 0 0 1 1 1 1 CFEM domain DUF4131 PF13567.1 EPE35073.1 - 8.8 5.6 10.5 1 8.7 3.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_18 PF12847.2 EPE35076.1 - 2.9e-13 50.3 0.0 4.3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE35076.1 - 1.3e-10 41.6 0.0 2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE35076.1 - 1.8e-10 40.5 0.0 2.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE35076.1 - 8.8e-08 32.4 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE35076.1 - 9.9e-08 32.0 0.0 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE35076.1 - 1.1e-07 32.2 0.0 2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE35076.1 - 2.5e-07 30.5 0.0 3.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE35076.1 - 1.2e-06 27.7 0.0 1.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EPE35076.1 - 1.7e-06 27.5 0.0 2.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EPE35076.1 - 0.00044 19.4 0.0 0.0006 19.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 EPE35076.1 - 0.0031 16.9 0.0 0.0043 16.4 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.7 EPE35076.1 - 0.0059 15.9 0.0 0.0083 15.4 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltrans_SAM PF10672.4 EPE35076.1 - 0.03 13.1 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase GMC_oxred_N PF00732.14 EPE35077.1 - 4.6e-58 196.7 0.0 6.7e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE35077.1 - 8.1e-33 113.7 0.0 1.2e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EPE35077.1 - 1.4e-05 24.2 0.4 2.2e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPE35077.1 - 0.00011 21.2 0.4 0.25 10.1 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EPE35077.1 - 0.00047 19.1 1.0 0.056 12.3 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPE35077.1 - 0.0041 17.0 0.0 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE35077.1 - 0.013 15.4 0.1 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EPE35077.1 - 0.039 12.5 0.2 0.057 12.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.1 EPE35077.1 - 0.045 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.12 EPE35077.1 - 0.15 11.1 1.4 0.22 10.6 0.1 1.8 2 0 0 2 2 2 0 Thi4 family adh_short PF00106.20 EPE35078.1 - 1.8e-17 63.7 0.0 2.6e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE35078.1 - 4.5e-06 26.4 0.0 6.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE35078.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EPE35078.1 - 0.0011 18.7 0.1 0.0029 17.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2126 PF09899.4 EPE35080.1 - 0.095 10.7 0.0 0.12 10.4 0.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Aldose_epim PF01263.15 EPE35081.1 - 8.6e-36 123.5 0.1 1e-35 123.3 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase F-box-like PF12937.2 EPE35082.1 - 1.1e-12 47.4 0.1 2.8e-12 46.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EPE35082.1 - 1.2e-07 31.2 11.8 0.024 14.2 0.0 5.9 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE35082.1 - 9.8e-07 28.4 17.1 0.02 14.6 0.2 6.3 4 2 3 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 EPE35082.1 - 0.004 17.0 19.2 32 5.0 0.0 10.6 12 1 1 13 13 13 0 Leucine Rich repeat F-box PF00646.28 EPE35082.1 - 0.0094 15.5 0.1 0.032 13.9 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 EPE35082.1 - 0.11 12.5 23.9 43 4.7 0.0 9.6 9 4 0 9 9 9 0 Leucine Rich Repeat Adeno_E4_34 PF04528.8 EPE35082.1 - 0.53 9.8 9.4 2.1 7.9 1.0 2.6 2 1 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region Chalcone PF02431.10 EPE35083.1 - 1.5e-60 203.9 0.0 2e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Glutaredoxin PF00462.19 EPE35084.1 - 3e-19 68.7 0.0 4.3e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.15 EPE35084.1 - 0.003 17.2 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EPE35084.1 - 0.0078 15.7 0.0 0.017 14.6 0.0 1.5 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 EPE35084.1 - 0.0079 16.3 0.1 0.013 15.7 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 EPE35084.1 - 0.0088 15.5 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF836 PF05768.9 EPE35084.1 - 0.012 15.8 0.0 0.016 15.4 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.1 EPE35084.1 - 0.021 14.3 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.1 EPE35084.1 - 0.048 13.4 0.0 0.075 12.8 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin domain GST_N_3 PF13417.1 EPE35084.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain BAG PF02179.11 EPE35085.1 - 2.1e-21 75.7 0.1 4.6e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EPE35085.1 - 3.5e-05 23.1 0.1 7.1e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L13 PF00572.13 EPE35086.1 - 2.8e-27 95.3 0.0 5.1e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 AMP-binding PF00501.23 EPE35087.1 - 1.2e-65 221.6 0.0 3.2e-65 220.1 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE35087.1 - 2.5e-17 63.6 0.1 4.9e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phage_Mu_Gp45 PF06890.7 EPE35087.1 - 0.032 13.6 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein Got1 PF04178.7 EPE35088.1 - 0.03 14.4 0.3 0.036 14.1 0.2 1.2 1 0 0 1 1 1 0 Got1/Sft2-like family AA_permease_2 PF13520.1 EPE35089.1 - 2.9e-94 316.0 34.6 3.6e-94 315.7 24.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE35089.1 - 2.5e-19 68.9 31.9 3.9e-19 68.3 22.1 1.2 1 0 0 1 1 1 1 Amino acid permease MAF_flag10 PF01973.13 EPE35090.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 Methyltransf_18 PF12847.2 EPE35091.1 - 1.2e-13 51.6 0.0 1.7e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE35091.1 - 3.8e-13 49.2 0.0 4.5e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE35091.1 - 2.2e-12 47.2 0.0 3.4e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE35091.1 - 1.2e-11 44.8 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE35091.1 - 6.9e-10 38.8 0.0 9.3e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE35091.1 - 1.8e-09 37.9 0.0 2.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE35091.1 - 9.3e-09 34.7 0.0 1.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EPE35091.1 - 9.1e-07 28.9 0.0 2.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPE35091.1 - 0.0012 18.4 0.0 0.0062 16.0 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 EPE35091.1 - 0.0018 17.8 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CheR PF01739.13 EPE35091.1 - 0.0063 15.8 0.0 2.5 7.3 0.0 2.1 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain MTS PF05175.9 EPE35091.1 - 0.024 13.9 0.0 0.084 12.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain N6_Mtase PF02384.11 EPE35091.1 - 0.032 13.3 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_24 PF13578.1 EPE35091.1 - 0.087 13.6 0.0 0.5 11.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 EPE35091.1 - 0.17 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NAAA-beta PF15508.1 EPE35092.1 - 2.6e-20 72.5 0.0 6.4e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Peptidase_M28 PF04389.12 EPE35093.1 - 1.7e-35 122.4 0.1 2.9e-35 121.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EPE35093.1 - 0.00018 21.0 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cache_3 PF14827.1 EPE35093.1 - 0.069 13.0 0.1 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Sensory domain of two-component sensor kinase Peptidase_M42 PF05343.9 EPE35093.1 - 0.16 10.6 0.0 0.29 9.8 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Pkinase PF00069.20 EPE35094.1 - 5.8e-38 130.5 0.0 8.9e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE35094.1 - 8.1e-28 97.1 0.0 1.2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE35094.1 - 0.00029 19.8 0.0 0.00042 19.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPE35094.1 - 0.047 12.7 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3535 PF12054.3 EPE35095.1 - 2.9e-143 477.6 2.9 7e-143 476.4 0.1 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EPE35095.1 - 2.1e-70 236.8 0.0 3.1e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE35095.1 - 1.2e-13 50.7 0.0 2.9e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 EPE35095.1 - 3.2e-13 48.5 15.6 0.017 15.1 0.0 10.0 11 0 0 11 11 11 4 HEAT repeat Vac14_Fab1_bd PF12755.2 EPE35095.1 - 3e-08 33.9 0.3 0.3 11.5 0.0 3.9 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EPE35095.1 - 3.1e-06 27.3 11.8 0.068 13.4 0.0 8.1 8 2 0 8 8 8 2 HEAT repeats CLASP_N PF12348.3 EPE35095.1 - 0.00021 20.6 0.3 0.27 10.5 0.1 3.7 2 2 1 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 EPE35095.1 - 0.0015 18.9 14.3 9.3 6.8 0.0 8.6 8 1 0 8 8 8 1 HEAT-like repeat Cnd1 PF12717.2 EPE35095.1 - 0.084 12.7 0.0 2 8.2 0.0 3.3 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HlyIII PF03006.15 EPE35098.1 - 1.7e-42 145.3 16.2 1.7e-42 145.3 11.2 3.1 3 0 0 3 3 3 1 Haemolysin-III related MFS_1 PF07690.11 EPE35098.1 - 3.9e-16 58.7 12.7 3.9e-16 58.7 8.8 3.3 2 1 1 3 3 3 1 Major Facilitator Superfamily PUCC PF03209.10 EPE35098.1 - 0.0011 17.7 13.4 0.0085 14.8 9.2 2.0 1 1 0 1 1 1 1 PUCC protein GST_N_3 PF13417.1 EPE35099.1 - 9.7e-12 44.9 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPE35099.1 - 2.3e-11 43.5 0.0 6.3e-11 42.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPE35099.1 - 4.2e-10 39.6 0.0 1.1e-09 38.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPE35099.1 - 1.6e-09 37.6 0.0 2.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPE35099.1 - 1.3e-08 34.6 0.0 2.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPE35099.1 - 4.9e-07 30.1 0.0 7.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-CCHC PF00098.18 EPE35100.1 - 6e-12 44.8 9.7 1.2e-05 24.9 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EPE35100.1 - 3.7e-08 32.8 0.2 7.1e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EPE35100.1 - 3.7e-07 29.7 5.7 0.00045 19.9 1.9 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EPE35100.1 - 0.00012 21.6 0.2 0.00025 20.6 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EPE35100.1 - 0.00045 19.8 6.0 0.19 11.3 0.5 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EPE35100.1 - 0.0088 15.6 10.5 0.3 10.8 0.4 2.8 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.1 EPE35100.1 - 0.039 13.4 0.1 0.039 13.4 0.1 3.0 2 1 1 3 3 3 0 Zinc knuckle IncA PF04156.9 EPE35101.1 - 0.0019 17.8 6.2 0.0019 17.8 4.3 6.2 2 1 3 5 5 5 3 IncA protein TMF_DNA_bd PF12329.3 EPE35101.1 - 0.002 17.9 54.0 0.39 10.5 5.8 8.0 5 2 2 7 7 7 4 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EPE35101.1 - 0.004 17.0 10.6 0.004 17.0 7.4 5.8 4 2 2 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EPE35101.1 - 0.0052 16.0 16.5 0.036 13.2 0.1 3.6 3 1 2 5 5 5 3 Reovirus sigma C capsid protein Mnd1 PF03962.10 EPE35101.1 - 0.0067 16.1 4.6 0.0067 16.1 3.2 6.1 3 2 1 5 5 5 1 Mnd1 family PspB PF06667.7 EPE35101.1 - 0.12 12.2 0.1 0.12 12.2 0.0 4.6 4 1 1 5 5 5 0 Phage shock protein B Lebercilin PF15619.1 EPE35101.1 - 2.9 7.2 49.9 0.04 13.3 3.7 7.2 5 1 2 8 8 8 0 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.6 EPE35101.1 - 3 7.6 60.3 0.51 10.1 6.2 5.4 4 2 1 5 5 5 0 Autophagy protein 16 (ATG16) SlyX PF04102.7 EPE35101.1 - 6.7 7.1 53.0 1.8 9.0 1.1 8.9 7 4 3 10 10 10 0 SlyX FAD_binding_4 PF01565.18 EPE35102.1 - 4.9e-20 71.4 0.5 7.8e-20 70.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_3 PF00933.16 EPE35103.1 - 1.8e-65 220.8 0.0 2.9e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE35103.1 - 4.9e-56 189.7 0.1 4.9e-56 189.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE35103.1 - 2.2e-22 78.7 0.2 5.5e-22 77.4 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 EPE35103.1 - 0.076 13.0 1.7 0.21 11.6 1.2 1.7 1 0 0 1 1 1 0 CARDB DUF829 PF05705.9 EPE35104.1 - 2.8e-53 181.1 0.0 3.2e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EPE35104.1 - 0.0015 18.4 0.1 0.0034 17.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sec39 PF08314.6 EPE35106.1 - 1.8e-195 650.9 0.0 2.1e-195 650.7 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 EPE35107.1 - 8.5e-05 22.4 0.0 0.00011 22.1 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX17 PF05051.8 EPE35107.1 - 0.07 13.1 0.4 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.3 EPE35107.1 - 0.12 12.5 0.4 0.21 11.7 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) RRM_1 PF00076.17 EPE35109.1 - 3.6e-19 68.1 0.0 5.2e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE35109.1 - 2.7e-16 59.2 0.0 4.1e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE35109.1 - 2.1e-12 46.6 0.0 3e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1793 PF08760.6 EPE35110.1 - 1e-71 240.3 0.1 1.9e-71 239.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) adh_short PF00106.20 EPE35111.1 - 1.1e-27 96.9 1.4 9.2e-24 84.2 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EPE35111.1 - 4.8e-26 92.0 0.0 3.3e-12 46.6 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE35111.1 - 5.9e-13 48.8 0.0 1.1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE35111.1 - 0.0053 16.2 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE35111.1 - 0.0079 16.2 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Ninjurin PF04923.7 EPE35112.1 - 0.064 12.9 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Ninjurin DUF4231 PF14015.1 EPE35112.1 - 0.069 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Anoctamin PF04547.7 EPE35112.1 - 0.12 11.0 0.1 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel ATP_transf PF09830.4 EPE35113.1 - 7.4e-16 57.7 0.0 1.4e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase CwfJ_C_1 PF04677.10 EPE35113.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Myb_DNA-bind_4 PF13837.1 EPE35114.1 - 0.0061 16.6 0.3 0.018 15.1 0.2 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPE35114.1 - 0.011 15.7 0.4 0.043 13.9 0.1 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Xpo1 PF08389.7 EPE35115.1 - 1.4e-37 128.8 0.8 1.8e-36 125.3 0.1 2.9 2 0 0 2 2 2 1 Exportin 1-like protein Phage_C PF12025.3 EPE35115.1 - 0.0057 16.5 0.3 0.05 13.5 0.0 2.6 2 0 0 2 2 2 1 Phage protein C SHR3_chaperone PF08229.6 EPE35115.1 - 0.0063 15.4 0.0 3.1 6.6 0.0 2.5 2 0 0 2 2 2 2 ER membrane protein SH3 HEAT PF02985.17 EPE35115.1 - 0.02 14.9 1.0 8.1 6.8 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat CHAD PF05235.9 EPE35115.1 - 0.1 12.1 0.4 9.9 5.6 0.0 3.0 3 0 0 3 3 3 0 CHAD domain Iso_dh PF00180.15 EPE35116.1 - 8.5e-126 419.5 0.0 1e-125 419.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.24 EPE35117.1 - 2.4e-10 39.9 5.5 4e-10 39.2 3.8 1.4 1 0 0 1 1 1 1 PHD-finger DUF4451 PF14616.1 EPE35118.1 - 4.8e-35 120.0 0.4 8.1e-35 119.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) MFS_1 PF07690.11 EPE35123.1 - 3.5e-21 75.3 31.7 4.7e-11 42.0 4.8 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EPE35123.1 - 4.9e-07 28.4 8.9 0.0001 20.8 2.5 3.2 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EPE35123.1 - 1.6e-06 27.7 0.7 1.8 8.4 0.0 3.8 3 0 0 3 3 3 3 MFS_1 like family LacY_symp PF01306.14 EPE35123.1 - 1.1 7.7 12.5 0.032 12.7 0.8 3.1 4 0 0 4 4 4 0 LacY proton/sugar symporter DUF1700 PF08006.6 EPE35125.1 - 0.099 11.9 8.2 0.14 11.4 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Metallophos PF00149.23 EPE35126.1 - 4e-14 52.4 2.4 7.7e-14 51.5 1.6 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPE35126.1 - 2.3e-07 30.7 0.0 4.2e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.11 EPE35127.1 - 9.3e-34 116.6 26.0 2.5e-33 115.2 18.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4064 PF13273.1 EPE35127.1 - 3.6 7.7 10.1 3.3 7.8 0.1 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) Fungal_trans PF04082.13 EPE35128.1 - 9.2e-12 44.3 0.3 1.8e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE35128.1 - 0.00026 20.8 16.9 0.00047 20.0 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 EPE35129.1 - 1.9e-07 30.8 0.1 6.9e-06 25.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE35129.1 - 2.2e-07 31.0 0.1 3.5e-07 30.3 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE35129.1 - 1.4e-05 24.8 0.0 3.2e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE35129.1 - 0.0012 18.4 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE35129.1 - 0.0049 16.1 0.0 0.047 12.9 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2974 PF11187.3 EPE35129.1 - 0.0055 16.1 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF2305 PF10230.4 EPE35129.1 - 0.015 14.7 0.0 0.04 13.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF2424 PF10340.4 EPE35129.1 - 0.032 12.8 0.0 0.15 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) DUF3089 PF11288.3 EPE35129.1 - 0.077 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Cupin_2 PF07883.6 EPE35130.1 - 9.6e-05 21.8 0.0 0.00033 20.1 0.0 1.8 1 1 0 1 1 1 1 Cupin domain Cu-oxidase_2 PF07731.9 EPE35130.1 - 0.062 12.8 0.1 0.091 12.2 0.1 1.3 1 0 0 1 1 1 0 Multicopper oxidase FAD_binding_3 PF01494.14 EPE35131.1 - 2.7e-20 72.7 0.8 1.6e-14 53.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 EPE35131.1 - 0.00042 19.2 0.0 0.001 17.9 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 EPE35131.1 - 0.016 15.1 0.9 0.042 13.8 0.6 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE35131.1 - 0.095 11.5 1.2 0.16 10.7 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain DUF531 PF04407.7 EPE35131.1 - 0.13 12.1 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF531) FAD_binding_3 PF01494.14 EPE35132.1 - 3.1e-15 56.1 0.7 2.8e-14 52.9 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE35132.1 - 6.2e-08 31.9 0.5 1.6e-07 30.5 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE35132.1 - 2e-07 30.9 0.5 4.4e-07 29.8 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE35132.1 - 5e-05 22.3 0.1 7.4e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPE35132.1 - 0.00026 20.9 0.3 0.00064 19.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE35132.1 - 0.00088 19.6 0.6 0.0022 18.3 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPE35132.1 - 0.0085 15.2 0.2 0.015 14.4 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE35132.1 - 0.013 14.3 3.2 0.034 12.9 2.2 1.7 1 1 1 2 2 2 0 FAD binding domain GIDA PF01134.17 EPE35132.1 - 0.048 12.5 1.8 0.08 11.7 0.5 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.19 EPE35132.1 - 0.14 11.1 0.5 0.86 8.5 0.3 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Glyco_tranf_2_4 PF13704.1 EPE35133.1 - 5.2e-08 33.0 0.1 1.3e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Fringe PF02434.11 EPE35133.1 - 0.077 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Fringe-like Asp PF00026.18 EPE35135.1 - 9.6e-54 182.7 0.4 1.1e-53 182.5 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EPE35135.1 - 6.7e-06 25.7 0.0 1.6e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EPE35135.1 - 0.00094 19.1 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EPE35135.1 - 0.047 14.1 0.0 5.6 7.5 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease AlaDh_PNT_N PF05222.10 EPE35136.1 - 2.8e-29 101.8 0.0 4.3e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EPE35136.1 - 1.7e-17 63.5 0.1 2.5e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 EPE35137.1 - 1.2e-18 67.5 0.2 1.7e-18 67.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE35137.1 - 1.5e-13 51.1 0.0 1.9e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Phage_AlpA PF05930.7 EPE35137.1 - 0.054 13.2 0.2 0.34 10.6 0.0 2.4 3 0 0 3 3 3 0 Prophage CP4-57 regulatory protein (AlpA) Thg1C PF14413.1 EPE35138.1 - 1.2e-51 173.4 1.9 1.7e-51 172.9 1.3 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EPE35138.1 - 1.6e-47 160.5 0.0 2.4e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase GEMIN8 PF15348.1 EPE35139.1 - 1.7 8.6 19.3 2.2 8.2 13.4 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 AAA_23 PF13476.1 EPE35141.1 - 2.7e-25 89.9 0.1 2.7e-25 89.9 0.1 7.9 2 1 1 3 3 2 1 AAA domain AAA_21 PF13304.1 EPE35141.1 - 1.7e-12 47.9 0.0 4e-05 23.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EPE35141.1 - 1.4e-10 40.8 0.0 4.6e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EPE35141.1 - 1.6e-10 40.1 115.0 3.2e-05 22.6 0.1 6.7 3 1 4 7 7 7 4 AAA domain AAA_15 PF13175.1 EPE35141.1 - 4.2e-07 29.3 27.0 7.7e-05 21.9 0.0 5.5 3 2 1 4 4 3 2 AAA ATPase domain AAA_29 PF13555.1 EPE35141.1 - 0.00049 19.5 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EPE35141.1 - 0.00084 18.6 53.7 0.011 14.9 37.2 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EPE35141.1 - 0.002 18.2 3.2 0.02 15.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EPE35141.1 - 0.0023 17.6 0.1 2.3 8.0 0.0 3.5 3 1 0 3 3 3 1 Part of AAA domain ABC_tran PF00005.22 EPE35141.1 - 0.043 14.1 0.0 0.043 14.1 0.0 6.9 3 2 0 4 4 2 0 ABC transporter AAA_16 PF13191.1 EPE35141.1 - 0.24 11.3 0.0 0.24 11.3 0.0 5.5 4 1 2 6 6 6 0 AAA ATPase domain Thioredoxin PF00085.15 EPE35142.1 - 4.9e-26 90.4 0.0 6.5e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EPE35142.1 - 2.3e-07 30.8 0.1 1.3e-05 25.2 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EPE35142.1 - 8.8e-07 29.1 0.2 3.6e-06 27.1 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EPE35142.1 - 0.0014 18.2 0.1 0.75 9.4 0.0 2.2 1 1 1 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EPE35142.1 - 0.0015 18.0 0.1 0.088 12.3 0.1 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_7 PF13899.1 EPE35142.1 - 0.0086 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.6 EPE35142.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 EPE35142.1 - 0.027 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF925 PF06042.6 EPE35143.1 - 0.087 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF925) WSC PF01822.14 EPE35144.1 - 5.4e-10 39.0 11.1 5.4e-10 39.0 7.7 2.2 2 0 0 2 2 2 1 WSC domain Adeno_E3_CR2 PF02439.10 EPE35144.1 - 0.04 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rifin_STEVOR PF02009.11 EPE35144.1 - 1.2 8.6 3.5 3.6 7.1 2.4 1.9 1 1 0 1 1 1 0 Rifin/stevor family NB-ARC PF00931.17 EPE35145.1 - 5e-08 32.1 0.0 7.7e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EPE35145.1 - 1.1e-06 28.8 0.1 0.00018 21.6 0.0 2.6 1 1 0 2 2 2 1 AAA domain DUF676 PF05057.9 EPE35145.1 - 6.4e-06 25.6 0.0 2.3e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPE35145.1 - 2.4e-05 24.3 1.7 5.2e-05 23.2 0.4 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_14 PF13173.1 EPE35145.1 - 0.00016 21.5 0.0 0.0015 18.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain PGAP1 PF07819.8 EPE35145.1 - 0.00019 21.1 0.1 0.00067 19.3 0.1 1.9 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPE35145.1 - 0.0012 18.5 0.0 0.0034 17.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE35145.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AAA_16 PF13191.1 EPE35145.1 - 0.015 15.3 0.6 0.16 11.8 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EPE35145.1 - 0.03 13.7 0.0 0.086 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain LCAT PF02450.10 EPE35145.1 - 0.052 12.5 0.1 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase AAA_17 PF13207.1 EPE35145.1 - 0.057 14.2 0.1 0.8 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EPE35145.1 - 0.098 12.3 0.1 0.42 10.2 0.1 2.1 2 1 0 2 2 2 0 NACHT domain DUF2710 PF10921.3 EPE35145.1 - 0.14 12.3 0.1 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2710) RabGGT_insert PF07711.6 EPE35146.1 - 0.076 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Rab geranylgeranyl transferase alpha-subunit, insert domain SprA_N PF14349.1 EPE35146.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Motility related/secretion protein P5-ATPase PF12409.3 EPE35146.1 - 0.93 9.3 4.5 1.8 8.4 3.1 1.4 1 0 0 1 1 1 0 P5-type ATPase cation transporter Sugar_tr PF00083.19 EPE35148.1 - 1.3e-50 172.3 19.8 1.9e-50 171.7 13.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE35148.1 - 1.5e-20 73.2 27.8 1.5e-20 73.2 19.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Dsh_C PF12316.3 EPE35151.1 - 0.025 14.6 2.3 0.03 14.4 1.6 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal MFS_1 PF07690.11 EPE35153.1 - 1.5e-24 86.4 31.9 1.5e-16 60.0 12.8 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily UPF0542 PF15086.1 EPE35153.1 - 0.14 11.8 0.3 1.2 8.8 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 DUF21 PF01595.15 EPE35153.1 - 6.9 5.9 12.2 9.6 5.4 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF21 Ferrochelatase PF00762.14 EPE35155.1 - 5.1e-91 304.9 0.0 5.9e-91 304.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase ACC_epsilon PF13822.1 EPE35155.1 - 0.15 12.4 0.8 0.88 9.9 0.0 2.2 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Ku PF02735.11 EPE35156.1 - 3.6e-42 144.0 0.0 1.7e-41 141.8 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EPE35156.1 - 1.9e-34 119.0 0.0 2.7e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EPE35156.1 - 1.2e-13 51.4 0.2 2.7e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EPE35156.1 - 7e-11 41.3 0.1 8.3e-09 34.7 0.1 2.8 1 1 1 2 2 2 1 SAP domain VWA_2 PF13519.1 EPE35156.1 - 0.031 14.3 0.1 0.059 13.4 0.1 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain ALIX_LYPXL_bnd PF13949.1 EPE35156.1 - 0.035 13.0 0.1 0.061 12.2 0.1 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV VWA PF00092.23 EPE35156.1 - 0.036 13.7 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain Complex1_51K PF01512.12 EPE35156.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Solute_trans_a PF03619.11 EPE35157.1 - 4.2e-83 278.8 21.0 5.1e-83 278.5 14.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Ndc1_Nup PF09531.5 EPE35158.1 - 0.28 9.5 8.7 0.4 9.0 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF572 PF04502.8 EPE35158.1 - 4.4 6.4 6.4 5.5 6.1 4.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Fungal_trans_2 PF11951.3 EPE35159.1 - 9.4e-08 31.0 0.2 1.5e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.10 EPE35160.1 - 1.3e-94 317.2 35.2 1.6e-94 317.0 24.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.16 EPE35162.1 - 1.1e-74 251.9 0.1 1.4e-74 251.5 0.1 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.15 EPE35162.1 - 2.3e-38 131.8 0.0 4e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Fungal_trans PF04082.13 EPE35163.1 - 1.8e-24 86.0 0.0 2.8e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE35163.1 - 4.5e-06 26.4 9.3 7.4e-06 25.7 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCCH PF00642.19 EPE35165.1 - 3.2 7.5 10.4 1.2 8.9 2.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Patatin PF01734.17 EPE35167.1 - 3.8e-26 92.2 0.1 3.5e-24 85.8 0.0 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase Ank_2 PF12796.2 EPE35167.1 - 4.7e-09 36.4 0.0 1.4e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE35167.1 - 1.4e-06 27.7 2.4 0.00022 20.8 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EPE35167.1 - 3.1e-06 27.2 0.1 0.0023 18.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE35167.1 - 3.9e-05 24.0 0.4 0.0093 16.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE35167.1 - 0.0002 21.3 0.6 0.054 13.7 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat HET PF06985.6 EPE35168.1 - 7.4e-34 116.8 0.7 2.1e-33 115.4 0.2 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Meiosis_expr PF15163.1 EPE35169.1 - 2.1 8.7 6.4 0.29 11.5 0.4 2.6 3 1 0 3 3 3 0 Meiosis-expressed Acetyltransf_7 PF13508.1 EPE35170.1 - 1.4e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE35170.1 - 2e-06 27.7 0.1 3.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE35170.1 - 0.0008 19.5 0.0 0.0014 18.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE35170.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tetraspannin PF00335.15 EPE35171.1 - 1.1e-06 28.1 1.0 2e-06 27.2 0.7 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF1077 PF06417.7 EPE35171.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) PX PF00787.19 EPE35172.1 - 1.8e-25 88.8 0.0 2.1e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 EPE35172.1 - 0.16 10.9 0.0 0.48 9.4 0.0 1.5 1 1 1 2 2 2 0 FAM91 N-terminus IPK PF03770.11 EPE35173.1 - 2.7e-57 193.5 0.0 5.7e-57 192.5 0.0 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF1848 PF08902.6 EPE35173.1 - 0.36 10.3 0.4 0.65 9.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Myb_DNA-bind_6 PF13921.1 EPE35175.1 - 1.6e-05 24.8 0.0 0.002 18.2 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPE35175.1 - 0.024 14.6 0.3 0.26 11.3 0.3 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPE35177.1 - 1.3e-12 47.5 2.2 3.4e-06 27.0 0.5 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPE35177.1 - 7.4e-12 45.1 0.8 1.7e-06 27.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_38 PF13936.1 EPE35177.1 - 0.038 13.5 0.2 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Myb_DNA-bind_2 PF08914.6 EPE35177.1 - 0.11 12.3 0.2 0.33 10.7 0.0 1.9 1 1 1 2 2 2 0 Rap1 Myb domain Glyco_hydro_16 PF00722.16 EPE35178.1 - 5.8e-44 149.5 5.2 5.8e-44 149.5 3.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EPE35178.1 - 0.045 13.7 13.4 0.11 12.4 9.3 1.6 1 0 0 1 1 1 0 Chitin recognition protein adh_short PF00106.20 EPE35179.1 - 5.5e-32 110.9 2.2 8.2e-32 110.4 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE35179.1 - 3.9e-25 89.0 0.4 4.7e-25 88.7 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE35179.1 - 6e-16 58.6 1.6 9.9e-16 57.9 1.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE35179.1 - 0.0024 17.3 0.3 0.32 10.3 0.1 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EPE35179.1 - 0.006 15.7 0.1 0.013 14.6 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EPE35179.1 - 0.037 13.6 0.5 0.037 13.6 0.4 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_PK PF05891.7 EPE35179.1 - 0.12 11.6 0.1 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase HHH_5 PF14520.1 EPE35179.1 - 0.37 10.9 2.5 0.78 9.9 1.7 1.6 1 1 0 1 1 1 0 Helix-hairpin-helix domain Bacteriocin_IId PF09221.5 EPE35179.1 - 2.7 7.9 10.5 0.28 11.1 1.7 2.5 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Pentapeptide_4 PF13599.1 EPE35181.1 - 2.2e-08 33.7 0.5 0.0056 16.4 0.0 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) zf-DHHC PF01529.15 EPE35182.1 - 3.6e-39 133.9 1.4 7.1e-39 132.9 1.0 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.12 EPE35182.1 - 0.056 12.9 0.2 0.056 12.9 0.1 2.0 2 0 0 2 2 2 0 Yip1 domain B12D PF06522.6 EPE35183.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PMT PF02366.13 EPE35184.1 - 6.1e-75 251.7 16.5 6.1e-75 251.7 11.5 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPE35184.1 - 4.7e-53 179.5 0.2 7.9e-53 178.8 0.1 1.4 1 0 0 1 1 1 1 MIR domain MFS_1 PF07690.11 EPE35185.1 - 0.0055 15.4 0.0 0.007 15.1 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF515 PF04415.7 EPE35185.1 - 0.16 10.1 0.1 1.2 7.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF515) ERCC4 PF02732.10 EPE35186.1 - 1.4e-16 60.5 0.1 2.4e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain Arrestin_C PF02752.17 EPE35187.1 - 1.3e-15 57.7 0.0 6.7e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EPE35187.1 - 9.2e-14 51.4 0.0 1.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EPE35187.1 - 0.00046 19.7 0.0 0.00092 18.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like DUF4177 PF13783.1 EPE35187.1 - 0.0012 18.4 0.0 0.0039 16.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4177) ATP12 PF07542.6 EPE35188.1 - 5.3e-37 126.4 0.0 7.6e-37 125.9 0.0 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein GMC_oxred_N PF00732.14 EPE35189.1 - 1.7e-54 185.0 0.0 2.2e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE35189.1 - 1.9e-32 112.5 0.0 3.8e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPE35189.1 - 0.0015 17.5 0.1 0.049 12.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE35189.1 - 0.0097 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPE35189.1 - 0.13 11.0 0.0 7.5 5.2 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EPE35189.1 - 0.15 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Rubis-subs-bind PF09273.6 EPE35190.1 - 2.8e-20 72.5 0.0 4.6e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EPE35190.1 - 3.2e-12 47.0 0.0 9.2e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-LITAF-like PF10601.4 EPE35191.1 - 7.6e-21 73.7 10.0 1.2e-20 73.1 7.0 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.5 EPE35191.1 - 0.53 10.2 0.1 0.53 10.2 0.0 2.6 3 0 0 3 3 3 0 Zinc ribbon domain Glyco_hydro_18 PF00704.23 EPE35192.1 - 1.2e-41 143.3 1.8 1.8e-41 142.7 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EPE35192.1 - 3e-07 30.2 0.1 0.00013 21.7 0.0 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EPE35192.1 - 0.00014 21.7 3.0 0.00014 21.7 2.1 4.2 5 0 0 5 5 5 1 Chitin recognition protein DUF3142 PF11340.3 EPE35192.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) LysM PF01476.15 EPE35195.1 - 1.9e-08 34.0 0.0 0.00023 20.9 0.0 2.3 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EPE35195.1 - 0.85 9.6 66.9 0.82 9.7 12.3 4.6 2 1 2 4 4 4 0 Chitin recognition protein PHY PF00360.15 EPE35196.1 - 2.7e-27 95.1 0.0 4.9e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region GAF PF01590.21 EPE35196.1 - 2.4e-19 69.9 0.0 6e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 GAF domain Response_reg PF00072.19 EPE35196.1 - 4.6e-15 55.6 0.0 1.4e-14 54.0 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EPE35196.1 - 5.7e-15 54.9 0.1 1.8e-14 53.3 0.1 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EPE35196.1 - 1.3e-09 37.9 0.6 3.4e-09 36.5 0.4 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EPE35196.1 - 1.6e-08 34.9 0.0 4.4e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold SapC PF07277.6 EPE35197.1 - 0.0081 15.4 0.4 0.015 14.6 0.3 1.5 1 0 0 1 1 1 1 SapC Uso1_p115_C PF04871.8 EPE35197.1 - 1.9 8.4 5.4 0.47 10.3 0.6 2.2 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3533 PF12051.3 EPE35198.1 - 4.4e-92 308.7 15.8 5.2e-92 308.5 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Zds_C PF08632.5 EPE35200.1 - 5.8e-31 105.6 1.1 1.2e-30 104.5 0.8 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ribosomal_60s PF00428.14 EPE35200.1 - 1.8 9.0 12.2 0.52 10.7 0.1 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein VHS PF00790.14 EPE35201.1 - 1e-33 115.9 0.7 2e-33 114.9 0.5 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EPE35201.1 - 1.4e-17 62.7 0.1 2.6e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPE35201.1 - 2.9e-15 55.5 0.0 4.6e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EPE35201.1 - 1.9e-14 52.9 0.1 3.4e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EPE35201.1 - 0.062 12.8 1.8 0.18 11.4 1.3 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Fe-ADH PF00465.14 EPE35202.1 - 1.4e-103 346.4 0.0 1.6e-103 346.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EPE35202.1 - 1.5e-14 53.8 0.0 2.8e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EPE35202.1 - 0.003 16.9 0.0 0.0067 15.8 0.0 1.5 1 0 0 1 1 1 1 Periplasmic binding protein RCC1 PF00415.13 EPE35203.1 - 4.5e-25 87.5 0.3 7.1e-06 26.1 0.0 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EPE35203.1 - 1.2e-10 41.3 0.0 3.8e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ank_4 PF13637.1 EPE35203.1 - 9.5e-07 29.1 0.1 3.7e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 EPE35203.1 - 2e-05 24.0 5.9 9.1e-05 21.9 0.1 3.7 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EPE35203.1 - 0.00091 19.2 0.0 0.012 15.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EPE35203.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) MutL PF13941.1 EPE35206.1 - 0.1 10.9 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 MutL protein HeLo PF14479.1 EPE35207.1 - 0.011 15.4 0.6 0.036 13.8 0.4 1.8 1 1 0 1 1 1 0 Prion-inhibition and propagation DUF310 PF03750.8 EPE35207.1 - 0.053 13.7 0.2 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF310) DUF16 PF01519.11 EPE35207.1 - 0.22 11.7 1.6 1.4 9.1 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fungal_trans PF04082.13 EPE35208.1 - 6e-15 54.8 2.0 9.9e-15 54.1 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE35208.1 - 6.8e-10 38.6 10.6 1e-09 38.1 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPSase_L_D2 PF02786.12 EPE35210.1 - 5.3e-112 372.2 0.2 7.9e-84 280.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 EPE35210.1 - 5.2e-46 156.5 0.0 1e-45 155.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EPE35210.1 - 4.4e-45 152.3 0.0 1.1e-44 151.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 EPE35210.1 - 7.2e-44 148.8 0.0 1.5e-43 147.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EPE35210.1 - 1e-42 144.8 0.2 5e-42 142.5 0.0 2.3 3 0 0 3 3 3 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EPE35210.1 - 3.8e-41 139.6 0.0 3.1e-20 72.3 0.0 3.0 3 0 0 3 3 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EPE35210.1 - 6.5e-36 123.7 0.1 1.1e-21 77.3 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain OTCace PF00185.19 EPE35210.1 - 6.6e-35 120.3 0.0 1.6e-34 119.0 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 EPE35210.1 - 5.3e-23 81.2 0.1 7.6e-12 44.6 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EPE35210.1 - 2e-21 75.7 0.0 2.6e-20 72.1 0.0 3.1 3 0 0 3 3 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EPE35210.1 - 2.3e-16 59.8 0.4 3.6e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EPE35210.1 - 4.8e-16 58.5 0.1 3e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EPE35210.1 - 2.1e-07 30.6 0.3 9.8e-06 25.1 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 EPE35210.1 - 2.9e-06 26.8 0.0 0.0024 17.4 0.0 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EPE35210.1 - 7.4e-06 25.9 0.4 0.1 12.4 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 EPE35210.1 - 0.00015 21.3 0.4 0.64 9.5 0.0 3.3 4 0 0 4 4 4 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 EPE35210.1 - 0.00056 19.3 0.0 0.0016 17.8 0.0 1.8 1 0 0 1 1 1 1 DJ-1/PfpI family Excalibur PF05901.6 EPE35212.1 - 0.11 12.9 0.5 6.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Excalibur calcium-binding domain DUF3664 PF12406.3 EPE35212.1 - 9.9 6.8 11.3 8.6 7.0 2.1 2.5 1 1 1 2 2 2 0 Surface protein Glyco_hydro_6 PF01341.12 EPE35213.1 - 5.8e-84 282.0 0.1 7.8e-84 281.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 S1-P1_nuclease PF02265.11 EPE35214.1 - 3.8e-73 246.2 0.0 4.3e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DUF2947 PF11163.3 EPE35214.1 - 0.15 11.6 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Peptidase_M24 PF00557.19 EPE35215.1 - 8.5e-09 35.2 0.0 1.2e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 TPR_12 PF13424.1 EPE35216.1 - 6.2e-57 189.4 50.5 9.5e-14 51.1 0.1 10.6 3 1 11 14 14 13 13 Tetratricopeptide repeat TPR_10 PF13374.1 EPE35216.1 - 1.5e-42 142.2 31.9 2.1e-06 27.4 0.0 13.3 12 2 2 14 14 13 8 Tetratricopeptide repeat NB-ARC PF00931.17 EPE35216.1 - 2.1e-14 53.0 0.0 4.5e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 EPE35216.1 - 1.9e-08 33.7 20.3 0.026 14.1 0.0 7.8 7 2 2 9 9 9 3 TPR repeat TPR_2 PF07719.12 EPE35216.1 - 2.1e-08 33.4 25.3 0.018 14.8 0.0 10.6 12 0 0 12 12 10 2 Tetratricopeptide repeat AAA_16 PF13191.1 EPE35216.1 - 3.5e-08 33.6 0.2 3.5e-07 30.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain TPR_16 PF13432.1 EPE35216.1 - 1.1e-07 32.3 8.5 0.65 10.7 0.1 7.1 7 1 1 8 8 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPE35216.1 - 1.8e-05 24.1 11.6 0.059 13.1 0.1 6.3 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPE35216.1 - 0.00016 21.2 18.4 0.26 11.1 0.2 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPE35216.1 - 0.00019 20.8 14.8 0.69 9.6 0.1 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EPE35216.1 - 0.00021 21.3 17.0 2.5 8.2 0.0 8.0 5 2 3 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EPE35216.1 - 0.00047 20.5 16.1 2.5 8.9 0.0 8.8 10 1 1 11 11 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPE35216.1 - 0.0035 17.6 11.3 0.45 10.8 0.0 6.2 6 1 2 8 8 7 1 Tetratricopeptide repeat AAA_22 PF13401.1 EPE35216.1 - 0.008 16.3 0.1 0.053 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPE35216.1 - 0.039 13.8 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EPE35216.1 - 0.085 12.5 0.0 0.25 11.0 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase TPR_6 PF13174.1 EPE35216.1 - 0.62 10.6 5.9 30 5.3 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EPE35216.1 - 1.6 8.9 5.5 4.1 7.5 0.5 4.0 3 1 1 4 4 3 0 Tetratricopeptide repeat Abhydrolase_5 PF12695.2 EPE35217.1 - 8.9e-06 25.5 0.2 9.9e-05 22.1 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EPE35217.1 - 9.3e-05 21.8 0.0 0.00037 19.8 0.0 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPE35217.1 - 0.0001 22.2 0.2 0.00049 20.0 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EPE35217.1 - 0.0032 16.5 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EPE35217.1 - 0.0093 15.5 0.0 0.021 14.3 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF726 PF05277.7 EPE35217.1 - 0.02 13.7 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF829 PF05705.9 EPE35217.1 - 0.046 13.4 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Ser_hydrolase PF06821.8 EPE35217.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF3505 PF12013.3 EPE35218.1 - 6.2e-10 39.2 0.5 1.8e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) zf-met2 PF12907.2 EPE35218.1 - 0.055 13.4 0.0 0.22 11.4 0.0 2.1 1 0 0 1 1 1 0 Zinc-binding GFA PF04828.9 EPE35219.1 - 1.2e-19 70.0 0.2 1.7e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 EPE35219.1 - 0.064 13.0 0.3 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NOB1_Zn_bind PF08772.6 EPE35219.1 - 2 8.2 5.1 3 7.7 0.2 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like FAA_hydrolase PF01557.13 EPE35220.1 - 1.5e-53 181.4 0.0 1.9e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SET PF00856.23 EPE35223.1 - 0.53 10.5 2.7 1.4 9.2 1.9 1.6 1 0 0 1 1 1 0 SET domain Herpes_UL6 PF01763.11 EPE35223.1 - 6.5 4.8 14.5 0.16 10.1 5.7 1.4 2 0 0 2 2 2 0 Herpesvirus UL6 like ADH_zinc_N PF00107.21 EPE35224.1 - 1.1e-12 47.6 0.0 2.1e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE35224.1 - 4.5e-08 32.8 2.2 3.9e-07 29.8 1.5 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPE35224.1 - 0.079 13.8 0.0 0.2 12.5 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.20 EPE35225.1 - 0.00065 18.9 0.0 0.00065 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pyr_redox_2 PF07992.9 EPE35227.1 - 7.1e-15 55.4 0.2 1.1e-14 54.7 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE35227.1 - 0.00028 19.8 0.1 0.0089 14.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EPE35227.1 - 0.0096 15.9 0.2 0.46 10.5 0.2 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 EPE35227.1 - 0.011 15.7 0.0 2.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain K_oxygenase PF13434.1 EPE35227.1 - 0.035 13.0 0.0 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EPE35227.1 - 0.055 11.9 0.1 0.13 10.6 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.1 EPE35227.1 - 3.5 7.7 6.8 4.2 7.4 0.3 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Ras PF00071.17 EPE35228.1 - 1e-44 151.7 0.0 1.5e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE35228.1 - 6.2e-16 58.9 0.0 1.1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE35228.1 - 4e-11 42.4 0.0 1.2e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPE35228.1 - 2.9e-05 23.3 0.0 4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPE35228.1 - 0.00073 19.4 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPE35228.1 - 0.00076 18.9 0.0 0.0032 16.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EPE35228.1 - 0.0016 18.3 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPE35228.1 - 0.0025 17.9 0.0 0.0095 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EPE35228.1 - 0.0037 16.7 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EPE35228.1 - 0.0078 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 EPE35228.1 - 0.0093 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EPE35228.1 - 0.025 14.8 0.2 0.076 13.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 EPE35228.1 - 0.025 14.2 0.0 0.065 12.8 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EPE35228.1 - 0.025 14.5 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 EPE35228.1 - 0.036 13.7 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EPE35228.1 - 0.037 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EPE35228.1 - 0.05 12.8 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 EPE35228.1 - 0.15 10.7 0.0 0.28 9.8 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit cobW PF02492.14 EPE35228.1 - 0.16 11.4 0.3 1.1 8.6 0.0 2.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EPE35228.1 - 0.18 11.2 0.0 10 5.5 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein adh_short PF00106.20 EPE35229.1 - 4.1e-24 85.3 0.1 5.9e-24 84.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE35229.1 - 3.9e-11 42.9 0.1 1.3e-10 41.2 0.0 1.8 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 EPE35229.1 - 1e-09 38.5 0.0 1.2e-09 38.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EPE35229.1 - 0.041 12.5 0.3 0.3 9.7 0.2 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EPE35229.1 - 0.061 12.3 0.1 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Glyco_hydro_2 PF00703.16 EPE35230.1 - 1.9e-11 44.3 0.1 1.1e-10 41.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EPE35230.1 - 8.5e-07 28.6 0.1 2.7e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EPE35230.1 - 4.5e-06 25.7 0.0 7.5e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain bZIP_1 PF00170.16 EPE35232.1 - 0.00014 21.7 8.5 0.00014 21.7 5.9 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EPE35232.1 - 0.00023 20.9 8.8 0.00048 19.8 6.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper FUSC-like PF12805.2 EPE35232.1 - 0.062 12.2 0.5 0.093 11.6 0.3 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS ITI_HC_C PF06668.7 EPE35232.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus CAF-1_p150 PF11600.3 EPE35232.1 - 0.68 9.2 13.6 1.1 8.6 9.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal bZIP_Maf PF03131.12 EPE35232.1 - 2.7 8.3 9.1 0.42 10.9 2.6 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor SET PF00856.23 EPE35233.1 - 9.9e-11 42.2 0.0 2.4e-09 37.7 0.0 2.5 2 1 0 2 2 2 1 SET domain DUF1081 PF06448.6 EPE35233.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) zf-MYND PF01753.13 EPE35233.1 - 6.5 6.7 10.0 15 5.6 7.0 1.6 1 0 0 1 1 1 0 MYND finger DUF3449 PF11931.3 EPE35235.1 - 1.6e-72 243.1 0.0 1.6e-72 243.1 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EPE35235.1 - 1.5e-11 43.6 0.0 3.1e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EPE35235.1 - 2.5e-08 33.8 3.6 5.3e-06 26.4 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPE35235.1 - 4.6e-08 32.9 4.3 1.8e-06 27.9 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EPE35235.1 - 0.00042 20.3 1.1 0.039 14.0 0.1 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 EPE35235.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-C2H2 PF00096.21 EPE35235.1 - 0.29 11.5 2.8 17 6.0 0.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Desulfoferrod_N PF06397.7 EPE35235.1 - 0.29 10.5 1.3 0.59 9.5 0.9 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Myb_CC_LHEQLE PF14379.1 EPE35235.1 - 0.44 10.1 6.6 16 5.2 4.6 2.7 1 1 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif zf-C2H2_4 PF13894.1 EPE35235.1 - 1.7 9.1 4.5 9.2 6.8 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DEAD PF00270.24 EPE35236.1 - 3.8e-40 137.1 0.3 8.5e-40 135.9 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE35236.1 - 2.7e-29 100.8 0.2 5.6e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 EPE35236.1 - 0.0083 15.4 0.4 0.016 14.5 0.1 1.5 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.1 EPE35236.1 - 0.011 15.3 0.4 0.028 14.0 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPE35236.1 - 0.015 15.0 0.1 0.037 13.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 EPE35236.1 - 0.038 13.7 0.2 0.13 11.9 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain ResIII PF04851.10 EPE35236.1 - 0.045 13.5 0.1 0.094 12.5 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit tRNA-synt_1b PF00579.20 EPE35236.1 - 0.1 11.7 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_22 PF13401.1 EPE35236.1 - 0.21 11.7 0.9 0.92 9.6 0.7 2.0 1 1 0 1 1 1 0 AAA domain BRCT PF00533.21 EPE35237.1 - 1.2e-06 28.6 0.0 3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Nodulin_late PF07127.6 EPE35238.1 - 0.0021 18.1 3.6 0.44 10.7 0.1 2.3 2 0 0 2 2 2 2 Late nodulin protein Squash PF00299.13 EPE35238.1 - 0.031 14.0 14.7 0.35 10.7 2.5 2.4 2 0 0 2 2 2 0 Squash family serine protease inhibitor Gamma-thionin PF00304.15 EPE35238.1 - 0.76 9.8 16.1 3.6 7.6 1.8 2.4 2 0 0 2 2 2 0 Gamma-thionin family PALP PF00291.20 EPE35239.1 - 5.3e-33 114.5 0.0 6.6e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 EPE35239.1 - 0.00039 19.4 0.0 0.0006 18.8 0.0 1.2 1 0 0 1 1 1 1 LytB protein ADH_N PF08240.7 EPE35240.1 - 5.5e-30 103.3 1.1 1.1e-29 102.3 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE35240.1 - 6.3e-24 83.9 1.7 7.2e-24 83.7 0.2 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE35240.1 - 0.00034 21.4 0.0 0.00093 20.0 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EPE35240.1 - 0.0076 16.8 0.0 0.024 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 EPE35240.1 - 0.022 14.3 1.4 0.035 13.6 0.3 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EPE35240.1 - 0.061 12.7 0.3 0.13 11.6 0.2 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Musclin PF11037.3 EPE35240.1 - 0.067 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Methyltransf_31 PF13847.1 EPE35240.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HI0933_like PF03486.9 EPE35240.1 - 0.079 11.4 0.6 0.13 10.6 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein Met_10 PF02475.11 EPE35240.1 - 0.15 11.6 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein AMP-binding PF00501.23 EPE35241.1 - 1.9e-80 270.3 0.0 3e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Beta-lactamase PF00144.19 EPE35242.1 - 1.5e-29 103.1 0.0 1.2e-28 100.1 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EPE35242.1 - 0.12 11.5 0.0 7.6 5.7 0.0 2.3 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase DUF3430 PF11912.3 EPE35243.1 - 0.032 14.0 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) INSIG PF07281.7 EPE35244.1 - 2.2e-49 167.4 0.1 3.1e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) GDPD PF03009.12 EPE35245.1 - 2.3e-18 66.6 0.0 3.2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family G-patch_2 PF12656.2 EPE35246.1 - 9.4e-23 79.8 2.7 1.3e-22 79.4 0.2 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site HSA PF07529.8 EPE35247.1 - 8.7e-19 67.0 10.6 1.4e-18 66.4 0.2 3.1 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 EPE35247.1 - 8e-12 45.0 1.0 8e-12 45.0 0.7 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPE35247.1 - 0.008 16.2 0.5 0.02 14.9 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_Cef PF11831.3 EPE35248.1 - 1.4e-59 201.1 4.4 1.4e-59 201.1 3.1 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 EPE35248.1 - 7e-20 70.8 5.9 5.3e-13 48.8 1.2 3.6 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPE35248.1 - 1.1e-19 70.1 4.4 7.2e-10 38.7 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 EPE35248.1 - 0.02 14.4 0.6 0.094 12.2 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Rap1_C PF11626.3 EPE35248.1 - 0.62 9.9 5.3 0.63 9.9 0.0 3.2 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Hexokinase_1 PF00349.16 EPE35249.1 - 3.5e-24 85.3 0.0 2.9e-23 82.3 0.0 2.0 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EPE35249.1 - 7.1e-20 71.2 0.0 4.8e-18 65.2 0.0 2.4 2 0 0 2 2 2 2 Hexokinase GILT PF03227.11 EPE35250.1 - 2.6e-12 46.5 0.1 4.4e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DcpS PF05652.7 EPE35251.1 - 5.8e-28 97.4 0.0 2.3e-27 95.5 0.0 2.0 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 EPE35251.1 - 6.2e-14 52.2 0.0 1.3e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding NifU PF01106.12 EPE35252.1 - 1.4 8.7 4.1 3.1 7.6 0.4 2.8 3 0 0 3 3 3 0 NifU-like domain RNA_pol PF00940.14 EPE35253.1 - 1e-160 534.6 0.0 1.5e-160 534.1 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EPE35253.1 - 2.2e-72 244.0 4.0 3.6e-72 243.3 2.7 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Cnl2_NKP2 PF09447.5 EPE35255.1 - 7.8e-25 86.3 0.3 1.4e-24 85.4 0.2 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein MRG PF05712.8 EPE35256.1 - 5.4e-54 182.0 0.0 8.9e-54 181.3 0.0 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EPE35256.1 - 1.1e-06 28.2 1.0 2.3e-06 27.2 0.7 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF742 PF05331.6 EPE35256.1 - 0.055 13.0 0.1 9.2 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF742) Ribosomal_L30 PF00327.15 EPE35257.1 - 4e-11 42.3 0.1 5e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sec6 PF06046.8 EPE35258.1 - 1.2e-165 551.8 9.1 1.2e-165 551.8 6.3 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF755 PF05501.6 EPE35258.1 - 0.033 14.2 0.2 0.074 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SPATA19 PF15212.1 EPE35258.1 - 0.033 14.2 0.6 0.13 12.2 0.5 1.9 2 0 0 2 2 2 0 Spermatogenesis-associated protein 19, mitochondrial NPV_P10 PF05531.7 EPE35258.1 - 0.21 11.8 2.7 27 5.1 0.0 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Aldo_ket_red PF00248.16 EPE35259.1 - 1.2e-64 217.8 0.0 1.9e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family CENP-Q PF13094.1 EPE35259.1 - 7.5e-23 81.3 1.8 7.5e-23 81.3 1.2 2.9 3 0 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit SPO22 PF08631.5 EPE35260.1 - 7.7e-50 169.5 4.0 1.2e-49 168.9 2.0 1.9 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_11 PF13414.1 EPE35260.1 - 0.00053 19.5 2.2 0.18 11.4 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 EPE35260.1 - 0.021 14.7 0.3 0.021 14.7 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPE35260.1 - 0.14 12.1 6.9 0.16 11.9 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.12 EPE35261.1 - 2.6e-108 361.8 21.4 3e-108 361.6 14.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Amidohydro_4 PF13147.1 EPE35262.1 - 3.3e-14 53.5 8.2 2.7e-13 50.5 5.7 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EPE35262.1 - 5.8e-09 36.0 0.3 2.8e-08 33.7 0.2 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EPE35262.1 - 3.1e-06 26.6 0.0 4.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EPE35262.1 - 0.0025 17.6 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase C2 PF00168.25 EPE35263.1 - 1.8e-22 78.9 0.0 2.4e-16 59.3 0.0 2.6 2 0 0 2 2 2 2 C2 domain HET PF06985.6 EPE35266.1 - 8.5e-17 61.6 0.6 3e-16 59.8 0.3 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Abhydrolase_1 PF00561.15 EPE35267.1 - 7.6e-17 61.6 0.1 1.1e-15 57.8 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE35267.1 - 3.5e-10 40.1 1.2 2.2e-09 37.5 0.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EPE35267.1 - 0.00062 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase AMP-binding PF00501.23 EPE35269.1 - 5e-77 259.0 0.0 6.4e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE35269.1 - 1.6e-13 51.4 0.4 5.8e-13 49.5 0.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF914 PF06027.7 EPE35270.1 - 1.7e-105 352.6 23.0 2.1e-105 352.2 15.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EPE35270.1 - 0.00044 20.2 11.4 0.00044 20.2 7.9 2.4 2 1 0 2 2 2 1 EamA-like transporter family FUSC-like PF12805.2 EPE35270.1 - 9.2 5.0 8.1 2.7 6.8 0.7 2.8 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS ubiquitin PF00240.18 EPE35271.1 - 0.0012 18.1 0.6 0.0027 17.0 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF1115 PF06544.7 EPE35272.1 - 0.0045 16.6 0.1 0.0052 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) GFA PF04828.9 EPE35273.1 - 1.1e-23 83.0 0.1 1.4e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-trcl PF13451.1 EPE35273.1 - 5.3 6.7 6.5 22 4.7 0.0 3.2 3 0 0 3 3 3 0 Probable zinc-binding domain K_oxygenase PF13434.1 EPE35274.1 - 1.8e-109 365.7 0.0 2.1e-109 365.5 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EPE35274.1 - 2.1e-10 40.9 0.0 6.4e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE35274.1 - 1e-09 38.3 0.0 1.5e-07 31.2 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPE35274.1 - 1.9e-06 27.9 0.0 4.2e-05 23.5 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE35274.1 - 0.0087 15.0 0.0 0.21 10.4 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Condensation PF00668.15 EPE35275.1 - 4.5e-23 81.5 0.0 1.3e-20 73.4 0.0 2.1 1 1 0 1 1 1 1 Condensation domain Asp PF00026.18 EPE35276.1 - 8.5e-63 212.4 11.7 1e-62 212.2 8.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EPE35276.1 - 0.00032 21.1 4.3 0.025 15.0 1.2 3.2 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EPE35276.1 - 0.0053 16.7 2.0 0.0084 16.0 0.5 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal CorA PF01544.13 EPE35277.1 - 1.2 8.1 5.1 1 8.3 0.1 2.2 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.6 EPE35277.1 - 6.5 7.2 9.7 1.5 9.3 0.4 2.8 1 1 1 3 3 3 0 Syntaxin 6, N-terminal Collagen PF01391.13 EPE35281.1 - 1.1e-24 85.6 113.3 1.4e-08 34.1 19.0 4.8 2 1 3 5 5 5 4 Collagen triple helix repeat (20 copies) WSC PF01822.14 EPE35281.1 - 1.8e-17 63.0 16.1 3e-17 62.3 11.1 1.4 1 0 0 1 1 1 1 WSC domain ABC_membrane PF00664.18 EPE35282.1 - 2.8e-91 305.7 36.4 6.3e-46 156.9 5.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPE35282.1 - 2e-69 232.1 0.0 3.4e-33 114.8 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPE35282.1 - 2.4e-13 49.8 0.0 0.00045 19.5 0.0 3.7 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE35282.1 - 1.9e-09 37.8 0.5 1.3 8.9 0.0 4.3 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EPE35282.1 - 3e-08 33.0 1.0 0.00058 19.3 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EPE35282.1 - 1e-07 32.1 0.2 0.0055 16.7 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EPE35282.1 - 2.5e-07 31.5 0.0 0.011 16.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPE35282.1 - 1.1e-06 27.9 0.1 0.34 10.0 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 EPE35282.1 - 1.8e-06 26.8 6.6 0.0034 16.0 0.0 3.3 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 EPE35282.1 - 3.3e-05 23.3 0.2 0.28 10.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EPE35282.1 - 0.00032 20.5 1.5 1.3 8.9 0.2 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EPE35282.1 - 0.0016 18.0 3.2 2.6 7.5 0.0 4.1 3 1 0 4 4 4 1 AAA domain AAA_28 PF13521.1 EPE35282.1 - 0.0018 18.2 0.4 0.53 10.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPE35282.1 - 0.0025 18.1 1.0 1.2 9.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 EPE35282.1 - 0.0025 17.6 2.0 2.3 7.9 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EPE35282.1 - 0.0033 17.5 4.8 1.7 8.8 0.3 4.1 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPE35282.1 - 0.0062 16.4 0.0 3.7 7.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 EPE35282.1 - 0.0095 14.6 0.1 2.4 6.7 0.0 2.6 2 1 0 2 2 2 1 G-protein alpha subunit AAA_14 PF13173.1 EPE35282.1 - 0.011 15.6 0.0 2.1 8.2 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_10 PF12846.2 EPE35282.1 - 0.029 13.7 2.2 17 4.6 0.1 3.9 4 0 0 4 4 4 0 AAA-like domain AAA_5 PF07728.9 EPE35282.1 - 0.036 13.7 1.8 8.9 6.0 0.0 3.4 5 0 0 5 5 3 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EPE35282.1 - 0.053 14.0 0.0 28 5.2 0.0 3.5 3 0 0 3 3 3 0 Miro-like protein MMR_HSR1 PF01926.18 EPE35282.1 - 0.15 12.0 0.9 14 5.6 0.0 3.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 EPE35282.1 - 0.2 11.3 2.3 21 4.8 0.0 3.6 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EPE35282.1 - 2.8 8.2 6.6 6.5 7.0 0.0 3.4 4 1 0 4 4 3 0 AAA domain IL28A PF15177.1 EPE35283.1 - 0.0042 16.6 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 Interleukin-28A TRI12 PF06609.8 EPE35284.1 - 4.2e-63 213.4 19.3 5.1e-63 213.2 13.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EPE35284.1 - 3.3e-21 75.4 38.3 1.5e-20 73.1 23.7 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE35284.1 - 9.9e-11 40.8 5.6 9.9e-11 40.8 3.9 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter DUF1049 PF06305.6 EPE35284.1 - 0.0027 17.1 0.1 0.0027 17.1 0.0 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF1049) Clr5 PF14420.1 EPE35285.1 - 2.3e-17 62.5 2.3 4.7e-17 61.6 1.6 1.6 1 0 0 1 1 1 1 Clr5 domain DUF2622 PF11080.3 EPE35287.1 - 0.11 12.4 0.2 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2622) MFS_1 PF07690.11 EPE35288.1 - 2.4e-39 135.0 35.6 2.4e-39 135.0 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE35288.1 - 1.5e-10 40.3 30.4 9.1e-10 37.6 21.0 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter COX4_pro_2 PF07835.7 EPE35288.1 - 0.38 10.7 3.2 1 9.3 0.1 2.7 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV UbiA PF01040.13 EPE35289.1 - 6.9e-33 113.9 16.6 9.8e-33 113.4 11.4 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Enterotoxin_HS1 PF08090.6 EPE35289.1 - 0.012 15.3 1.7 0.012 15.3 1.2 2.2 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 Med3 PF11593.3 EPE35289.1 - 0.1 11.8 6.9 0.13 11.4 4.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Myb_DNA-bind_6 PF13921.1 EPE35290.1 - 8.5e-05 22.5 0.1 0.00044 20.2 0.1 2.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain Sugar_tr PF00083.19 EPE35291.1 - 2.3e-114 382.4 27.3 2.8e-114 382.1 18.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE35291.1 - 6.4e-23 81.0 40.1 7e-18 64.4 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rad50_zn_hook PF04423.9 EPE35292.1 - 1.2e-05 24.6 7.9 0.044 13.2 0.0 5.6 4 1 1 5 5 5 3 Rad50 zinc hook motif Lar_restr_allev PF14354.1 EPE35292.1 - 4 7.7 24.4 3.6 7.9 6.0 4.8 2 2 1 3 3 3 0 Restriction alleviation protein Lar Glyco_hydro_76 PF03663.9 EPE35293.1 - 9.4e-134 446.4 7.5 1.3e-133 446.0 5.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Ank_2 PF12796.2 EPE35294.1 - 4e-56 187.3 6.4 1.1e-15 57.6 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EPE35294.1 - 9.2e-33 110.4 16.3 0.00019 21.0 0.0 8.9 8 1 1 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 EPE35294.1 - 4.8e-32 109.7 13.1 3e-10 40.3 0.2 6.5 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE35294.1 - 7.5e-32 106.1 7.6 0.00029 20.7 0.1 9.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 EPE35294.1 - 4.5e-24 83.9 14.6 1.8e-06 28.0 0.3 8.4 1 1 7 9 9 9 5 Ankyrin repeats (many copies) MOZART1 PF12554.3 EPE35294.1 - 0.063 12.7 0.1 3.8 7.0 0.0 2.9 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated tRNA-synt_2 PF00152.15 EPE35297.1 - 3.1e-96 322.0 0.0 4.4e-96 321.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EPE35297.1 - 0.0052 16.0 0.0 0.21 10.7 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EPE35297.1 - 0.012 15.1 0.2 0.11 12.0 0.1 2.1 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) ANTH PF07651.11 EPE35298.1 - 1.2e-70 237.4 1.5 1.6e-70 237.0 1.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EPE35298.1 - 4.4e-10 39.4 0.0 7.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain MAT1 PF06391.8 EPE35299.1 - 1e-30 106.8 8.8 1.3e-30 106.4 6.1 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EPE35299.1 - 0.00029 20.4 5.0 0.00063 19.3 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE35299.1 - 0.0081 15.8 4.9 0.014 15.0 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE35299.1 - 0.0085 16.0 8.0 0.017 15.1 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE35299.1 - 0.039 13.7 7.3 0.11 12.3 5.0 1.7 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 EPE35299.1 - 0.04 13.6 7.7 0.11 12.2 5.4 1.7 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 EPE35299.1 - 0.045 13.3 4.4 0.14 11.7 1.0 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EPE35299.1 - 1.8 8.4 5.8 2.5 7.9 1.7 2.7 1 1 1 2 2 2 0 zf-RING of BARD1-type protein CS PF04969.11 EPE35300.1 - 3.9e-17 62.5 0.1 6.8e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 CS domain PrgH PF09480.5 EPE35300.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Ribophorin_II PF05817.9 EPE35301.1 - 3.8e-24 84.8 0.2 4.7e-24 84.5 0.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II TauD PF02668.11 EPE35302.1 - 7.5e-53 179.8 0.0 8.8e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3336 PF11815.3 EPE35303.1 - 1.9e-38 131.2 3.0 3.3e-38 130.4 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EPE35303.1 - 2e-22 80.1 0.0 4.2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Fer4_11 PF13247.1 EPE35305.1 - 0.041 13.7 1.6 0.054 13.3 1.1 1.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Polysacc_deac_1 PF01522.16 EPE35307.1 - 2.8e-16 59.2 0.0 4.9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase RE_HpaII PF09561.5 EPE35307.1 - 0.065 12.4 0.0 3.4 6.7 0.0 2.1 1 1 1 2 2 2 0 HpaII restriction endonuclease Fungal_lectin PF07938.7 EPE35308.1 - 2.8e-05 23.5 2.0 0.00013 21.3 0.1 2.4 1 1 0 2 2 2 1 Fungal fucose-specific lectin EBP50_C-term PF09007.6 EPE35308.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 EBP50, C-terminal HAD_2 PF13419.1 EPE35309.1 - 2.9e-30 105.7 0.0 3.9e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPE35309.1 - 6.3e-05 23.4 0.0 0.00024 21.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF481 PF04338.7 EPE35311.1 - 0.017 14.8 0.7 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF481 Dynamin_N PF00350.18 EPE35312.1 - 3.4e-28 98.5 0.0 4.9e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EPE35312.1 - 0.00014 21.7 0.0 0.00036 20.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPE35312.1 - 0.0016 18.9 0.0 0.0041 17.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EPE35312.1 - 0.011 15.0 0.1 0.37 10.0 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.1 EPE35312.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.11 EPE35312.1 - 0.031 13.3 0.1 4.5 6.3 0.0 2.3 2 0 0 2 2 2 0 AIG1 family AAA_28 PF13521.1 EPE35312.1 - 0.054 13.4 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L16 PF00252.13 EPE35315.1 - 4.9e-31 107.2 0.1 6.2e-31 106.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.21 EPE35316.1 - 8.5e-27 92.5 0.0 9.7e-27 92.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Z1 PF10593.4 EPE35317.1 - 0.0091 15.2 7.3 0.018 14.2 5.1 1.5 1 0 0 1 1 1 1 Z1 domain IncA PF04156.9 EPE35317.1 - 0.0096 15.5 19.8 0.0096 15.5 13.7 2.6 3 0 0 3 3 3 1 IncA protein DUF3818 PF12825.2 EPE35317.1 - 0.016 13.9 3.4 1.3 7.6 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) DUF3450 PF11932.3 EPE35317.1 - 0.1 11.8 16.4 4.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.14 EPE35317.1 - 0.72 7.6 15.6 0.33 8.7 7.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EPE35317.1 - 1.9 8.5 18.3 2.8 8.0 7.0 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 EPE35317.1 - 2 6.7 14.7 0.45 8.8 7.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) ADIP PF11559.3 EPE35317.1 - 2.1 8.2 24.8 0.75 9.6 12.1 3.2 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Sipho_Gp157 PF05565.6 EPE35317.1 - 3.9 7.0 19.4 17 4.9 0.1 3.1 2 1 1 3 3 3 0 Siphovirus Gp157 DUF4055 PF13264.1 EPE35317.1 - 4.1 7.5 8.2 4.9 7.2 1.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) APG6 PF04111.7 EPE35317.1 - 6.9 5.6 25.5 1.6 7.6 13.6 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Vac_Fusion PF02346.11 EPE35317.1 - 7 6.1 7.7 4 6.9 2.0 2.9 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Selenoprotein_S PF06936.6 EPE35317.1 - 7.2 6.0 12.9 15 5.0 8.9 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF972 PF06156.8 EPE35317.1 - 7.8 6.9 23.0 12 6.2 6.6 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Collagen PF01391.13 EPE35318.1 - 0.0016 17.9 8.1 0.0032 16.9 5.6 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) S4 PF01479.20 EPE35320.1 - 2.9e-11 42.5 0.0 5.9e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EPE35320.1 - 8.2e-08 32.5 0.3 1.5e-07 31.6 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_S18 PF01084.15 EPE35321.1 - 1.7e-09 37.4 0.0 3.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 PRP1_N PF06424.7 EPE35322.1 - 1.8e-52 177.2 5.3 1.8e-52 177.2 3.7 1.9 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EPE35322.1 - 2.8e-32 108.2 33.1 0.00028 21.2 0.1 14.4 5 3 10 15 15 14 10 Tetratricopeptide repeat TPR_19 PF14559.1 EPE35322.1 - 4.7e-23 81.3 21.3 2.7e-08 34.0 0.2 10.0 5 3 5 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 EPE35322.1 - 3.1e-22 78.6 21.0 3e-06 27.7 0.4 8.3 6 2 4 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 EPE35322.1 - 2e-15 56.1 18.6 3.1e-05 23.5 0.0 8.6 5 3 2 9 9 9 5 TPR repeat TPR_2 PF07719.12 EPE35322.1 - 3.8e-13 48.2 13.5 0.58 10.2 0.1 10.0 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPE35322.1 - 2.1e-08 33.7 7.6 4.6 7.7 0.0 10.1 9 1 3 12 12 11 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPE35322.1 - 2.5e-08 33.3 24.0 9.1e-05 21.6 4.6 6.0 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPE35322.1 - 2.2e-07 30.2 0.5 1.6 8.4 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPE35322.1 - 4e-07 29.8 5.2 0.11 12.5 0.0 6.1 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPE35322.1 - 4.2e-07 29.2 0.1 14 5.7 0.0 7.7 7 1 1 8 8 7 0 Tetratricopeptide repeat NARP1 PF12569.3 EPE35322.1 - 3.7e-06 25.9 9.7 0.017 13.8 0.0 5.9 4 1 3 7 7 7 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EPE35322.1 - 1.3e-05 25.2 13.2 24 5.6 0.0 9.8 11 0 0 11 11 9 0 Tetratricopeptide repeat Suf PF05843.9 EPE35322.1 - 1.9e-05 24.5 0.1 0.67 9.6 0.0 4.9 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_21 PF09976.4 EPE35322.1 - 0.00028 20.8 14.0 0.0097 15.8 0.8 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPE35322.1 - 0.00072 19.3 5.5 0.066 13.0 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE35322.1 - 0.0013 18.3 1.7 45 4.2 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 EPE35322.1 - 0.012 15.6 0.0 2.5 8.3 0.0 4.2 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.4 EPE35322.1 - 0.059 11.9 2.5 8.7 4.7 0.0 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF3808) TPR_10 PF13374.1 EPE35322.1 - 0.32 10.9 6.2 9.8 6.2 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_26 PF02156.10 EPE35323.1 - 1.5e-13 50.9 0.2 2.4e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CFEM PF05730.6 EPE35325.1 - 0.0062 16.3 2.6 0.0062 16.3 1.8 1.9 2 0 0 2 2 2 1 CFEM domain YkuD PF03734.9 EPE35325.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain DUF3824 PF12868.2 EPE35326.1 - 1.5e-05 25.9 6.1 1.5e-05 25.9 4.2 12.0 5 3 7 12 12 12 2 Domain of unknwon function (DUF3824) Gly-zipper_OmpA PF13436.1 EPE35326.1 - 1.6 8.4 31.8 0.083 12.5 1.9 5.0 4 1 1 5 5 5 0 Glycine-zipper containing OmpA-like membrane domain CopD PF05425.8 EPE35326.1 - 7.8 6.7 5.9 22 5.3 0.4 3.4 3 1 0 3 3 3 0 Copper resistance protein D PPR_3 PF13812.1 EPE35328.1 - 5.7e-09 35.5 2.9 0.00071 19.6 0.0 7.2 8 0 0 8 8 8 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EPE35328.1 - 1.8e-08 34.2 0.2 4 7.4 0.0 6.7 6 1 1 7 7 7 3 PPR repeat family PPR PF01535.15 EPE35328.1 - 0.0001 22.0 1.7 19 5.5 0.0 6.9 8 0 0 8 8 8 1 PPR repeat TPR_19 PF14559.1 EPE35328.1 - 0.037 14.3 0.2 8.8 6.7 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPE35328.1 - 2.4 9.0 6.7 32 5.5 0.0 5.6 8 0 0 8 8 8 0 Tetratricopeptide repeat PUF PF00806.14 EPE35329.1 - 6.4e-12 44.2 0.0 0.075 12.5 0.0 7.4 8 0 0 8 8 8 4 Pumilio-family RNA binding repeat Piwi PF02171.12 EPE35330.1 - 2.6e-56 190.8 1.0 1.8e-37 128.9 0.0 2.3 1 1 1 2 2 2 2 Piwi domain DUF1785 PF08699.5 EPE35330.1 - 8.1e-14 50.7 0.0 1.8e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EPE35330.1 - 1.2e-13 50.4 0.1 2.3e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 PAZ domain ThiF PF00899.16 EPE35332.1 - 3.3e-28 98.1 0.0 5.6e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EPE35332.1 - 0.0029 17.7 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EPE35332.1 - 0.075 12.1 0.0 0.83 8.7 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain dCMP_cyt_deam_1 PF00383.17 EPE35333.1 - 2.9e-27 94.2 0.6 4.2e-27 93.7 0.4 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 EPE35333.1 - 2e-05 24.8 0.0 4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE35333.1 - 0.00091 20.0 0.1 0.0023 18.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EPE35333.1 - 0.0027 17.1 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase XOO_2897-deam PF14440.1 EPE35333.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase NmrA PF05368.8 EPE35334.1 - 2.6e-16 59.6 0.0 3e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE35334.1 - 0.048 13.6 0.0 0.18 11.7 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding His_biosynth PF00977.16 EPE35335.1 - 2.9e-48 164.1 1.1 1.8e-47 161.5 0.8 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EPE35335.1 - 5.6e-29 100.9 0.0 9.2e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EPE35335.1 - 1.2e-10 41.2 0.0 4.5e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EPE35335.1 - 3.5e-07 29.9 0.0 9e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EPE35335.1 - 0.0013 18.2 0.0 0.0051 16.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 Dus PF01207.12 EPE35335.1 - 0.1 11.3 0.0 0.3 9.8 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) PhyH PF05721.8 EPE35336.1 - 1.5e-24 87.1 0.0 2.1e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NUDIX PF00293.23 EPE35337.1 - 5.5e-09 35.7 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain CFEM PF05730.6 EPE35337.1 - 0.00076 19.2 2.1 0.0018 18.0 1.4 1.6 1 0 0 1 1 1 1 CFEM domain NAD_binding_10 PF13460.1 EPE35338.1 - 4e-07 30.2 0.0 4.9e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE35338.1 - 0.00052 18.8 0.0 0.00069 18.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPE35338.1 - 0.0021 18.0 0.1 0.024 14.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EPE35338.1 - 0.012 15.0 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EPE35338.1 - 0.041 14.1 0.0 0.099 12.9 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EPE35338.1 - 0.071 12.7 0.1 0.91 9.1 0.1 2.1 1 1 0 1 1 1 0 KR domain DapB_N PF01113.15 EPE35338.1 - 0.11 12.4 0.1 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EPE35338.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Uds1 PF15456.1 EPE35339.1 - 3.5e-36 123.9 4.4 3.5e-36 123.9 3.1 1.8 2 0 0 2 2 2 1 Up-regulated During Septation CCDC155 PF14662.1 EPE35339.1 - 0.054 13.0 0.2 0.094 12.3 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Wbp11 PF09429.5 EPE35339.1 - 0.061 13.3 0.7 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 WW domain binding protein 11 DUF1662 PF07878.6 EPE35339.1 - 0.066 12.9 0.7 0.34 10.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1662) IncA PF04156.9 EPE35339.1 - 0.36 10.4 2.1 0.6 9.6 1.4 1.3 1 0 0 1 1 1 0 IncA protein Peptidase_M1 PF01433.15 EPE35340.1 - 9.2e-71 238.9 0.0 1.2e-70 238.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EPE35340.1 - 4.7e-46 155.9 0.0 8.8e-46 155.0 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EPE35340.1 - 4e-19 68.9 0.2 7.6e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EPE35340.1 - 0.36 10.8 3.3 1.3 8.9 1.8 2.3 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Catalase PF00199.14 EPE35343.1 - 9e-73 245.1 0.0 1.1e-72 244.9 0.0 1.0 1 0 0 1 1 1 1 Catalase zf-C3HC4_2 PF13923.1 EPE35344.1 - 1.6e-07 31.2 9.5 2.7e-07 30.5 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE35344.1 - 1.4e-06 27.8 5.9 2.4e-06 27.1 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE35344.1 - 1.4e-06 27.8 8.5 2.5e-06 27.0 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPE35344.1 - 5.2e-06 26.2 6.3 3.5e-05 23.5 4.8 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EPE35344.1 - 6.9e-06 25.8 8.4 1.2e-05 25.0 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPE35344.1 - 1.8e-05 24.3 5.7 3.3e-05 23.5 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPE35344.1 - 0.14 11.8 7.2 0.19 11.4 3.8 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-MIZ PF02891.15 EPE35344.1 - 0.6 9.6 9.0 1.3 8.5 6.3 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger UCH PF00443.24 EPE35345.1 - 7.8e-49 166.1 0.0 1.8e-48 164.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPE35345.1 - 5.9e-14 52.2 0.0 4.2e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ERG4_ERG24 PF01222.12 EPE35346.1 - 1.2e-137 458.9 22.4 1.4e-137 458.7 15.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Transp_cyt_pur PF02133.10 EPE35347.1 - 3.3e-96 322.5 43.2 3.9e-96 322.2 29.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 EPE35348.1 - 2.9e-27 95.5 0.0 5.1e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPE35348.1 - 4e-20 71.9 0.0 7e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EPE35349.1 - 1.7e-22 79.5 0.4 3.5e-22 78.5 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE35349.1 - 0.00016 21.5 6.3 0.00029 20.6 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.9 EPE35350.1 - 1.6e-144 481.9 15.2 2.1e-144 481.4 10.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EPE35350.1 - 0.21 10.6 9.6 1.6 7.7 3.2 2.8 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 Glyco_hydro_17 PF00332.13 EPE35351.1 - 9.6e-05 21.5 1.0 0.00018 20.6 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Dynamin_N PF00350.18 EPE35352.1 - 1.6e-18 67.0 0.0 3e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EPE35352.1 - 9.7e-07 28.7 0.0 8.1e-06 25.7 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.15 EPE35352.1 - 2.5e-06 26.4 0.1 8.5e-06 24.7 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region FeoB_N PF02421.13 EPE35352.1 - 0.0032 16.7 0.0 0.35 10.1 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Miro PF08477.8 EPE35352.1 - 0.014 15.8 0.0 0.045 14.2 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein SpoVG PF04026.7 EPE35352.1 - 0.092 12.7 0.0 1.4 8.9 0.0 2.7 3 0 0 3 3 3 0 SpoVG MFS_2 PF13347.1 EPE35353.1 - 9.3e-10 37.4 20.0 9.3e-10 37.4 13.9 2.1 2 1 0 2 2 2 1 MFS/sugar transport protein PrgI PF12666.2 EPE35353.1 - 5.3 7.2 12.5 0.27 11.4 0.8 3.4 3 0 0 3 3 3 0 PrgI family protein Zn_clus PF00172.13 EPE35354.1 - 5.2e-07 29.4 34.4 0.00014 21.6 6.2 2.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Pol_alpha_B_N PF08418.5 EPE35354.1 - 8.5 5.8 11.3 36 3.7 7.8 2.2 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MFS_1 PF07690.11 EPE35356.1 - 4.8e-08 32.1 42.5 4.8e-08 32.1 29.5 2.9 2 2 0 2 2 2 1 Major Facilitator Superfamily RCR PF12273.3 EPE35357.1 - 3.6e-13 50.2 3.0 4.8e-13 49.7 2.1 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM51 PF15345.1 EPE35357.1 - 0.0001 22.1 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Hum_adeno_E3A PF05393.6 EPE35357.1 - 0.00068 19.2 0.1 0.0009 18.8 0.1 1.3 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein GRP PF07172.6 EPE35357.1 - 0.0034 17.8 0.4 0.009 16.4 0.3 1.7 1 1 0 1 1 1 1 Glycine rich protein family SCIMP PF15050.1 EPE35357.1 - 0.0038 17.1 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 SCIMP protein Rhabdo_glycop PF00974.13 EPE35357.1 - 0.0052 15.0 0.0 0.0063 14.8 0.0 1.2 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein Herpes_gE PF02480.11 EPE35357.1 - 0.0083 14.4 0.0 0.0094 14.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.1 EPE35357.1 - 0.012 15.8 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2207 PF09972.4 EPE35357.1 - 0.023 13.2 0.0 0.025 13.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ASFV_J13L PF05568.6 EPE35357.1 - 0.052 13.0 0.1 0.078 12.5 0.0 1.3 1 1 0 1 1 1 0 African swine fever virus J13L protein EphA2_TM PF14575.1 EPE35357.1 - 0.054 13.8 0.0 0.12 12.7 0.0 1.6 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Myc_target_1 PF15179.1 EPE35357.1 - 0.099 12.2 0.3 0.099 12.2 0.2 1.7 1 1 0 1 1 1 0 Myc target protein 1 DUF3328 PF11807.3 EPE35357.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) ODV-E18 PF10717.4 EPE35357.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4381 PF14316.1 EPE35357.1 - 0.29 11.2 2.3 0.37 10.8 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) RTA1 PF04479.8 EPE35358.1 - 1.9e-42 145.3 7.6 1.9e-42 145.3 5.3 1.5 2 0 0 2 2 2 1 RTA1 like protein GET2 PF08690.5 EPE35359.1 - 3.6e-06 26.4 1.0 0.00011 21.6 0.7 2.7 1 1 0 1 1 1 1 GET complex subunit GET2 ADH_N PF08240.7 EPE35360.1 - 8.1e-22 77.0 7.8 3.1e-19 68.7 1.2 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE35360.1 - 7.7e-17 61.0 0.0 1.4e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE35360.1 - 0.00012 22.9 0.0 0.00024 21.9 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EPE35360.1 - 0.012 14.7 0.4 0.019 14.0 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 EPE35360.1 - 0.027 14.6 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_18 PF12847.2 EPE35360.1 - 0.028 15.0 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Gp_dh_N PF00044.19 EPE35360.1 - 0.09 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EPE35360.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain S10_plectin PF03501.10 EPE35361.1 - 1.9e-40 136.6 0.2 3.1e-40 135.9 0.2 1.4 1 0 0 1 1 1 1 Plectin/S10 domain Glyco_hydro_43 PF04616.9 EPE35361.1 - 2.3e-21 76.1 1.4 3.1e-20 72.4 1.0 2.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Telomere_Sde2 PF13019.1 EPE35362.1 - 2.7e-66 222.2 2.5 4.2e-66 221.6 1.7 1.3 1 0 0 1 1 1 1 Telomere stability and silencing LacI PF00356.16 EPE35362.1 - 0.11 12.1 0.8 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Nop14 PF04147.7 EPE35362.1 - 0.57 8.0 17.1 0.75 7.6 11.8 1.2 1 0 0 1 1 1 0 Nop14-like family Troponin-I_N PF11636.3 EPE35362.1 - 2 8.2 8.6 7.7 6.2 6.0 2.0 1 0 0 1 1 1 0 Troponin I residues 1-32 Peptidase_M20 PF01546.23 EPE35363.1 - 1.3e-18 67.1 0.1 1.9e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPE35363.1 - 5.4e-06 26.1 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain B12D PF06522.6 EPE35364.1 - 1.2e-07 31.3 0.1 2.2e-07 30.4 0.0 1.4 2 0 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.17 EPE35365.1 - 4.3e-16 58.2 0.0 7.2e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE35365.1 - 3.4e-15 55.7 0.0 5.6e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE35365.1 - 2.2e-08 33.8 0.0 4.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EPE35366.1 - 1.9e-17 62.4 1.6 4.3e-05 23.2 0.0 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat SRA1 PF07304.6 EPE35366.1 - 1.3e-09 37.9 1.4 1.3e-09 37.9 0.9 2.8 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EPE35366.1 - 5.6e-07 29.5 0.1 1.6e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 DUF1365 PF07103.6 EPE35367.1 - 6.9e-27 94.1 0.0 1.1e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) adh_short PF00106.20 EPE35368.1 - 2.3e-12 47.1 0.8 3.3e-12 46.6 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE35368.1 - 1.3e-06 28.2 0.1 2e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE35368.1 - 0.0011 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2863 PF11062.3 EPE35369.1 - 0.00051 18.2 0.0 0.00087 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2863) HLH PF00010.21 EPE35370.1 - 4.7e-07 29.4 0.0 1.3e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain eIF3_subunit PF08597.5 EPE35370.1 - 0.57 9.7 10.4 0.99 8.9 7.2 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RR_TM4-6 PF06459.7 EPE35370.1 - 9.9 5.9 7.6 17 5.2 5.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IMS PF00817.15 EPE35371.1 - 3.3e-24 85.3 0.0 6.4e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EPE35371.1 - 2e-08 34.1 0.2 5.4e-08 32.8 0.1 1.7 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EPE35371.1 - 0.00088 19.1 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Axin_b-cat_bind PF08833.5 EPE35372.1 - 0.23 11.2 3.3 1.5 8.5 0.9 3.2 2 0 0 2 2 2 0 Axin beta-catenin binding domain Cupin_2 PF07883.6 EPE35373.1 - 2.4e-16 58.9 0.1 2.4e-16 58.9 0.0 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EPE35373.1 - 3.4e-06 26.5 0.0 4.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EPE35373.1 - 1.1e-05 25.0 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.9 EPE35373.1 - 0.00012 22.0 0.1 0.00027 20.9 0.0 1.6 1 1 0 1 1 1 1 ARD/ARD' family Cupin_3 PF05899.7 EPE35373.1 - 0.00028 20.2 0.1 0.0006 19.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) GPI PF06560.6 EPE35373.1 - 0.0082 15.1 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Cupin_6 PF12852.2 EPE35373.1 - 0.0089 15.6 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 Cupin EutQ PF06249.7 EPE35373.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ MarB PF13999.1 EPE35373.1 - 0.037 13.5 0.1 0.19 11.3 0.0 2.0 1 1 1 2 2 2 0 MarB protein JmjC PF02373.17 EPE35373.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase CtaG_Cox11 PF04442.9 EPE35374.1 - 2.1e-57 193.1 0.0 3.5e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DZR PF12773.2 EPE35376.1 - 1.5 8.7 4.1 0.79 9.5 0.1 2.3 3 0 0 3 3 3 0 Double zinc ribbon PLDc_2 PF13091.1 EPE35377.1 - 3.8e-15 55.7 0.1 3.7e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.3 EPE35377.1 - 0.046 12.6 0.0 2.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB PLDc PF00614.17 EPE35377.1 - 0.87 9.4 3.3 23 4.9 0.0 3.0 3 0 0 3 3 3 0 Phospholipase D Active site motif Peptidase_M6 PF05547.6 EPE35378.1 - 7.5e-09 34.1 0.2 0.00055 18.1 2.0 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 Ank_2 PF12796.2 EPE35379.1 - 1.7e-19 69.9 1.2 4.9e-10 39.6 0.1 4.5 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPE35379.1 - 1.4e-15 56.1 4.3 4.9e-05 22.9 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EPE35379.1 - 4.1e-12 46.2 1.8 0.049 14.1 0.0 6.8 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE35379.1 - 3.4e-11 43.0 5.1 0.0002 21.4 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE35379.1 - 1.4e-06 27.9 6.0 0.33 11.3 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat bZIP_2 PF07716.10 EPE35380.1 - 2.3e-05 24.1 23.0 7.7e-05 22.4 16.0 2.0 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EPE35380.1 - 4.1e-05 23.4 19.0 9.3e-05 22.3 13.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor IncA PF04156.9 EPE35380.1 - 0.018 14.6 5.6 0.034 13.7 3.9 1.5 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EPE35380.1 - 0.04 13.9 10.8 0.11 12.5 7.5 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_Maf PF03131.12 EPE35380.1 - 0.22 11.8 21.6 0.042 14.1 12.3 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor V_ATPase_I PF01496.14 EPE35380.1 - 0.27 9.0 1.4 0.38 8.5 1.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.7 EPE35380.1 - 1.3 8.8 6.0 3.2 7.5 4.2 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 APG6 PF04111.7 EPE35380.1 - 2.1 7.2 10.1 4.6 6.2 7.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 NAD_binding_10 PF13460.1 EPE35381.1 - 1e-16 61.4 0.0 7.1e-16 58.7 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EPE35381.1 - 2.3e-16 59.7 0.0 2.8e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EPE35381.1 - 0.0056 16.1 0.0 0.017 14.5 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 EPE35383.1 - 1.5e-35 122.6 0.0 2.1e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EPE35383.1 - 1.4e-12 46.9 0.0 2.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPE35383.1 - 3.6e-05 23.5 0.1 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE35383.1 - 0.0058 15.8 0.0 0.033 13.3 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EPE35383.1 - 0.081 11.6 0.1 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family BAAT_C PF08840.6 EPE35383.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SKG6 PF08693.5 EPE35385.1 - 6.9e-05 22.0 0.3 0.00017 20.8 0.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.13 EPE35385.1 - 0.00034 20.3 0.2 0.00076 19.2 0.2 1.5 1 0 0 1 1 1 1 Glycophorin A Herpes_gE PF02480.11 EPE35385.1 - 0.0065 14.7 0.0 0.0091 14.3 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SSP160 PF06933.6 EPE35385.1 - 0.012 13.6 10.7 0.016 13.2 7.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mid2 PF04478.7 EPE35385.1 - 0.025 14.0 0.3 0.043 13.2 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.1 EPE35385.1 - 0.028 14.1 0.2 0.043 13.5 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family BatD PF13584.1 EPE35385.1 - 0.039 12.5 0.0 0.052 12.1 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Plasmodium_Vir PF05795.6 EPE35385.1 - 0.089 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1517 PF07466.6 EPE35385.1 - 0.098 11.6 0.5 0.15 10.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Syndecan PF01034.15 EPE35385.1 - 0.12 12.0 0.0 0.43 10.2 0.0 1.9 2 0 0 2 2 2 0 Syndecan domain Phage_Coat_B PF05356.6 EPE35385.1 - 0.13 11.9 0.3 0.29 10.8 0.2 1.6 1 0 0 1 1 1 0 Phage Coat protein B EphA2_TM PF14575.1 EPE35385.1 - 0.15 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EPE35385.1 - 0.16 11.5 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 dCMP_cyt_deam_1 PF00383.17 EPE35386.1 - 2.2e-24 85.0 0.1 2.9e-24 84.6 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EPE35386.1 - 0.00033 20.3 0.0 0.0005 19.7 0.0 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 EPE35386.1 - 0.022 14.6 3.4 0.044 13.6 0.2 2.4 2 1 0 3 3 3 0 Bd3614-like deaminase NADH_u_ox_C PF12853.2 EPE35387.1 - 6.5e-34 115.5 0.0 1e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 EPE35387.1 - 5.6e-30 103.4 0.1 9.3e-30 102.7 0.1 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Swi3 PF07962.7 EPE35388.1 - 3.6e-30 103.4 0.6 5.7e-30 102.7 0.4 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DSHCT PF08148.7 EPE35389.1 - 5.8e-60 201.6 0.3 1.5e-59 200.2 0.2 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EPE35389.1 - 7.4e-21 74.3 0.0 2.7e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE35389.1 - 9.8e-07 28.5 0.0 3.4e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE35389.1 - 0.02 14.7 0.1 0.18 11.5 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CitT PF12431.3 EPE35390.1 - 3.3e-05 23.8 1.4 4.5 7.4 0.0 5.2 5 0 0 5 5 5 2 Transcriptional regulator L_biotic_typeA PF04604.8 EPE35390.1 - 0.00037 20.0 3.7 0.65 9.6 0.0 4.9 5 1 1 6 6 6 1 Type-A lantibiotic DUF2482 PF10655.4 EPE35390.1 - 0.0046 16.9 6.1 6.7 6.8 0.1 4.7 5 1 1 6 6 6 1 Hypothetical protein of unknown function (DUF2482) ATP-cone PF03477.11 EPE35390.1 - 0.076 13.4 19.6 1.9 8.9 5.3 4.5 1 1 2 3 3 3 0 ATP cone domain DUF433 PF04255.9 EPE35390.1 - 0.097 12.1 2.3 49 3.4 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF433) Rsbr_N PF08678.5 EPE35390.1 - 0.13 12.1 4.2 4.3 7.2 0.1 3.2 2 1 1 3 3 3 0 Rsbr N terminal Toprim_C_rpt PF13368.1 EPE35390.1 - 0.78 10.2 14.4 0.96 9.9 0.1 4.5 3 1 3 6 6 6 0 Topoisomerase C-terminal repeat Profilin PF00235.14 EPE35390.1 - 2.3 8.3 14.9 18 5.4 0.6 5.1 1 1 4 6 6 6 0 Profilin Nuc-transf PF10127.4 EPE35390.1 - 5.3 6.3 9.5 1.7 7.8 0.6 2.5 1 1 0 2 2 2 0 Predicted nucleotidyltransferase AAT PF03417.11 EPE35393.1 - 5.3e-36 124.1 0.0 7.1e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EPE35393.1 - 1.9e-05 24.9 0.0 3.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Lactamase_B PF00753.22 EPE35395.1 - 2.8e-21 76.0 0.2 8.6e-21 74.4 0.1 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPE35395.1 - 5.7e-06 26.0 0.3 1e-05 25.2 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_3 PF13738.1 EPE35396.1 - 1.3e-22 80.8 0.0 4.8e-22 79.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE35396.1 - 7.2e-12 44.2 0.1 8.2e-10 37.4 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EPE35396.1 - 1.2e-10 41.2 0.0 3.2e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EPE35396.1 - 2.1e-06 26.9 0.0 0.02 13.8 0.0 3.4 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPE35396.1 - 4.8e-06 26.6 0.0 0.0021 17.9 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE35396.1 - 0.00025 20.8 0.1 0.0047 16.6 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding TEX13 PF15186.1 EPE35396.1 - 0.14 11.7 0.1 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Glyoxalase_2 PF12681.2 EPE35399.1 - 0.0011 19.6 0.0 0.0023 18.5 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EPE35399.1 - 0.017 15.1 0.0 0.059 13.3 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AAA_12 PF13087.1 EPE35401.1 - 7.9e-39 133.1 0.0 1.3e-38 132.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPE35401.1 - 6.4e-26 91.3 0.0 1.5e-25 90.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EPE35401.1 - 5.4e-08 32.6 0.1 1.6e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EPE35401.1 - 5.7e-08 32.5 0.0 0.00016 21.3 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EPE35401.1 - 3.6e-07 29.8 0.0 8.2e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EPE35401.1 - 5.8e-05 22.2 0.5 0.019 13.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EPE35401.1 - 0.00053 19.8 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EPE35401.1 - 0.0016 17.7 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.16 EPE35401.1 - 0.023 14.0 0.1 0.071 12.3 0.0 2.0 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EPE35401.1 - 0.044 13.9 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 EPE35401.1 - 0.094 12.1 0.2 0.95 8.8 0.0 2.3 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain DEAD PF00270.24 EPE35401.1 - 0.098 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.1 EPE35401.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EPE35402.1 - 6.8e-16 57.4 6.6 0.059 13.2 0.0 7.9 9 0 0 9 9 9 5 WD domain, G-beta repeat Nup160 PF11715.3 EPE35402.1 - 0.14 10.2 0.0 0.53 8.3 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 COPI_C PF06957.6 EPE35402.1 - 2.8 6.3 7.3 5.3 5.4 5.0 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF605 PF04652.11 EPE35402.1 - 2.8 7.2 17.9 0.07 12.5 4.8 2.1 2 0 0 2 2 2 0 Vta1 like DUF3375 PF11855.3 EPE35404.1 - 0.087 11.5 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Apc15p PF05841.6 EPE35405.1 - 0.026 15.2 4.7 0.026 15.2 3.3 2.4 2 1 1 3 3 3 0 Apc15p protein DUF904 PF06005.7 EPE35405.1 - 0.76 10.1 10.9 4.3 7.7 7.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EPE35405.1 - 7 6.2 7.9 7 6.2 1.1 3.1 2 1 0 3 3 3 0 Septum formation initiator Fes1 PF08609.5 EPE35405.1 - 9.9 6.7 7.7 18 5.9 1.8 3.0 2 1 1 3 3 3 0 Nucleotide exchange factor Fes1 bZIP_1 PF00170.16 EPE35406.1 - 0.013 15.4 0.3 0.013 15.4 0.2 6.1 5 1 1 6 6 6 0 bZIP transcription factor MFS_2 PF13347.1 EPE35407.1 - 8.5e-10 37.5 7.2 8.5e-10 37.5 5.0 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein Na_H_Exchanger PF00999.16 EPE35409.1 - 3.1e-69 233.3 39.0 3.9e-69 233.0 27.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PIG-X PF08320.7 EPE35410.1 - 2.1e-62 210.0 0.0 3e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 DUF1183 PF06682.7 EPE35411.1 - 1.3e-85 287.8 1.6 1.7e-85 287.4 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) COX8 PF02285.10 EPE35411.1 - 0.62 9.6 3.1 1.6 8.2 0.6 2.5 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIII BRE1 PF08647.6 EPE35412.1 - 1.3e-27 95.5 8.2 1.3e-27 95.5 5.7 6.7 5 3 0 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EPE35412.1 - 3.9e-08 33.1 9.8 6.4e-08 32.5 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE35412.1 - 9.4e-08 31.6 7.4 1.5e-07 31.0 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE35412.1 - 1.6e-07 30.8 11.0 2.8e-07 30.0 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE35412.1 - 1.3e-06 28.1 7.1 2.2e-06 27.4 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPE35412.1 - 3.4e-06 26.6 10.5 5.7e-06 25.9 7.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPE35412.1 - 0.00012 21.6 5.5 0.00029 20.4 3.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EPE35412.1 - 0.0041 16.8 1.6 0.0079 15.9 1.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EPE35412.1 - 0.0069 16.2 6.7 0.013 15.3 4.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING HALZ PF02183.13 EPE35412.1 - 0.0088 15.7 0.8 0.0088 15.7 0.6 7.5 8 0 0 8 8 7 1 Homeobox associated leucine zipper DUF2501 PF10696.4 EPE35412.1 - 0.0091 15.9 0.0 0.032 14.2 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2501) Reo_sigmaC PF04582.7 EPE35412.1 - 0.01 15.0 33.7 0.22 10.6 4.2 4.8 1 1 2 5 5 5 0 Reovirus sigma C capsid protein zf-RING_4 PF14570.1 EPE35412.1 - 0.032 13.8 8.2 0.13 11.8 5.8 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EPE35412.1 - 0.052 13.0 3.0 0.095 12.2 2.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 EPE35412.1 - 0.11 12.3 10.0 0.049 13.4 5.1 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) FYVE PF01363.16 EPE35412.1 - 0.95 9.4 11.2 14 5.6 7.9 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_4 PF13894.1 EPE35412.1 - 5.2 7.6 5.8 15 6.2 0.0 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-FCS PF06467.9 EPE35412.1 - 6.2 6.5 9.1 51 3.6 4.4 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif NPV_P10 PF05531.7 EPE35413.1 - 0.079 13.2 0.5 0.19 12.0 0.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Aldo_ket_red PF00248.16 EPE35414.1 - 8.9e-48 162.5 0.0 1.1e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.9 EPE35415.1 - 0.00062 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EPE35415.1 - 0.1 11.8 0.2 0.1 11.8 0.2 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Glyco_hydro_1 PF00232.13 EPE35416.1 - 6.1e-150 499.3 0.0 7.6e-150 499.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Mod_r PF07200.8 EPE35417.1 - 0.0002 21.3 3.9 0.0002 21.3 2.7 3.3 1 1 2 3 3 3 2 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 EPE35417.1 - 0.00065 19.3 31.2 0.0028 17.2 6.1 3.2 1 1 2 3 3 2 2 IncA protein CorA PF01544.13 EPE35417.1 - 0.0044 16.0 4.2 0.0044 16.0 2.9 2.4 2 0 0 2 2 1 1 CorA-like Mg2+ transporter protein Vac_Fusion PF02346.11 EPE35417.1 - 0.0078 15.6 6.3 0.58 9.6 0.1 3.5 2 1 1 3 3 3 2 Chordopoxvirus fusion protein DUF972 PF06156.8 EPE35417.1 - 0.052 13.9 18.5 0.052 13.9 0.6 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Cir_Bir_Yir PF06022.6 EPE35417.1 - 0.075 12.2 0.2 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir THOC7 PF05615.8 EPE35417.1 - 0.1 12.8 24.6 4.3 7.5 3.2 3.3 1 1 1 2 2 2 0 Tho complex subunit 7 DUF3359 PF11839.3 EPE35417.1 - 0.13 12.6 7.3 6.7 7.1 2.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3359) HALZ PF02183.13 EPE35417.1 - 0.14 11.9 23.7 0.47 10.2 0.1 4.5 4 1 1 5 5 5 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 EPE35417.1 - 0.19 11.4 18.1 5.2 6.8 12.5 2.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ERM PF00769.14 EPE35417.1 - 0.2 11.1 31.8 0.18 11.3 19.1 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family bZIP_1 PF00170.16 EPE35417.1 - 0.31 11.0 0.0 0.31 11.0 0.0 5.0 3 2 1 4 4 3 0 bZIP transcription factor Prefoldin PF02996.12 EPE35417.1 - 0.42 10.2 13.4 2.3 7.8 0.1 3.9 3 1 1 4 4 4 0 Prefoldin subunit Prefoldin_2 PF01920.15 EPE35417.1 - 0.88 9.3 13.0 0.28 10.9 0.1 3.4 3 2 0 3 3 3 0 Prefoldin subunit Scaffolding_pro PF11418.3 EPE35417.1 - 1.1 9.5 14.8 2.6 8.4 1.3 3.6 1 1 1 3 3 3 0 Phi29 scaffolding protein DUF342 PF03961.8 EPE35417.1 - 1.6 7.0 10.1 0.028 12.8 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TBPIP PF07106.8 EPE35417.1 - 1.8 8.1 20.5 0.44 10.0 1.3 3.2 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rab5-bind PF09311.6 EPE35417.1 - 2.6 7.9 27.4 0.1 12.4 0.7 2.5 1 1 1 2 2 2 0 Rabaptin-like protein DUF4140 PF13600.1 EPE35417.1 - 6.1 7.3 22.3 0.56 10.6 1.5 4.8 1 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.7 EPE35417.1 - 9.7 6.0 9.6 0.45 10.3 0.3 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DivIC PF04977.10 EPE35419.1 - 0.01 15.3 16.2 0.19 11.2 0.1 3.3 3 0 0 3 3 3 0 Septum formation initiator HALZ PF02183.13 EPE35419.1 - 0.014 15.0 14.7 0.27 10.9 0.2 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF465 PF04325.8 EPE35419.1 - 0.026 14.1 9.4 3.9 7.2 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF465) CCDC144C PF14915.1 EPE35419.1 - 0.25 10.2 19.9 0.39 9.5 13.8 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TPR_MLP1_2 PF07926.7 EPE35419.1 - 0.73 9.5 25.7 3.6 7.3 3.6 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.7 EPE35419.1 - 1.3 9.1 19.2 1 9.5 0.7 3.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF904 PF06005.7 EPE35419.1 - 1.7 9.0 22.4 0.59 10.4 1.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF904) DUF1875 PF08961.5 EPE35419.1 - 2.9 7.1 13.6 2.9 7.1 0.3 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF1875) bZIP_1 PF00170.16 EPE35419.1 - 7.3 6.6 18.8 2.4 8.1 0.5 3.6 3 0 0 3 3 3 0 bZIP transcription factor FimP PF09766.4 EPE35420.1 - 2.6 7.0 7.9 4.3 6.3 5.5 1.3 1 1 0 1 1 1 0 Fms-interacting protein Glyco_hydro_16 PF00722.16 EPE35421.1 - 2.2e-10 40.1 0.0 6.2e-10 38.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Y_phosphatase3 PF13350.1 EPE35422.1 - 1.9e-35 122.5 0.0 2.9e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EPE35422.1 - 0.00078 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 EPE35422.1 - 0.083 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.15 EPE35422.1 - 0.094 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EPE35422.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Nuc_recep-AF1 PF11825.3 EPE35422.1 - 0.67 9.8 3.2 0.96 9.3 2.2 1.4 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 adh_short PF00106.20 EPE35423.1 - 6.4e-32 110.7 0.6 8.2e-32 110.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE35423.1 - 7.3e-31 107.7 0.1 8.3e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE35423.1 - 1.2e-11 44.6 0.1 1.7e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPE35423.1 - 0.00068 19.6 2.2 0.0015 18.5 1.4 1.9 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EPE35423.1 - 0.00078 18.5 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EPE35423.1 - 0.0025 17.9 0.0 0.0037 17.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EPE35423.1 - 0.0047 16.6 0.2 0.0047 16.6 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EPE35423.1 - 0.015 14.7 0.3 0.1 11.9 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EPE35423.1 - 0.19 11.3 1.3 0.38 10.3 0.3 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EPE35424.1 - 4.9e-22 78.6 0.0 8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE35424.1 - 2.3e-07 30.6 0.1 3.8e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE35424.1 - 8.3e-07 29.0 0.1 1.1e-06 28.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EPE35424.1 - 0.00054 19.1 0.0 0.0022 17.2 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EPE35424.1 - 0.0093 15.9 0.5 0.02 14.9 0.1 1.7 1 1 1 2 2 2 1 NADH(P)-binding Pantoate_transf PF02548.10 EPE35424.1 - 0.056 12.5 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase THF_DHG_CYH_C PF02882.14 EPE35424.1 - 0.06 12.4 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EPE35424.1 - 0.096 12.4 0.3 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DSBA PF01323.15 EPE35425.1 - 4.5e-13 49.1 0.0 5.2e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain NAD_binding_10 PF13460.1 EPE35426.1 - 4.2e-21 75.7 0.1 5.6e-21 75.3 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding VESA1_N PF12785.2 EPE35427.1 - 0.34 9.8 4.1 0.44 9.4 2.8 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Cobl PF09469.5 EPE35428.1 - 0.24 11.3 1.1 0.88 9.5 0.8 1.9 1 1 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Moulting_cycle PF04870.11 EPE35428.1 - 3.8 6.5 6.9 0.72 8.8 0.6 1.9 1 1 1 2 2 2 0 Moulting cycle Hom_end_hint PF05203.11 EPE35429.1 - 0.79 9.4 4.8 0.94 9.1 3.3 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Host_attach PF10116.4 EPE35429.1 - 0.81 9.9 7.3 0.92 9.7 4.4 1.5 1 1 0 1 1 1 0 Protein required for attachment to host cells GIDA_assoc_3 PF13932.1 EPE35429.1 - 1.6 8.8 5.2 0.23 11.5 0.7 1.8 2 1 0 2 2 2 0 GidA associated domain 3 Sigma70_ECF PF07638.6 EPE35429.1 - 7.1 6.2 14.3 0.53 9.9 5.3 2.0 1 1 1 2 2 2 0 ECF sigma factor FLO_LFY PF01698.11 EPE35429.1 - 7.4 5.2 12.4 8.2 5.1 8.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein CAF1 PF04857.15 EPE35430.1 - 2.1e-64 217.3 0.0 3.1e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 EPE35431.1 - 5.9e-18 64.3 1.2 8.1e-18 63.9 0.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family HATPase_c PF02518.21 EPE35432.1 - 4.8e-19 68.1 0.0 9.8e-19 67.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE35432.1 - 6.9e-18 64.6 0.0 3e-17 62.6 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EPE35432.1 - 1.6e-13 50.4 1.0 1.7e-12 47.1 0.0 3.2 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain Sugar_tr PF00083.19 EPE35433.1 - 4.2e-102 342.0 19.8 5.1e-102 341.7 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE35433.1 - 3.1e-22 78.7 35.2 5.9e-14 51.5 8.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Beta-lactamase PF00144.19 EPE35434.1 - 2.4e-45 155.0 0.0 6.4e-45 153.6 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase F-box-like PF12937.2 EPE35435.1 - 0.00015 21.4 1.0 0.00032 20.3 0.2 1.9 2 0 0 2 2 2 1 F-box-like DZR PF12773.2 EPE35435.1 - 0.00056 19.6 0.4 0.0097 15.7 0.1 2.6 2 1 0 2 2 2 1 Double zinc ribbon F-box PF00646.28 EPE35435.1 - 0.0035 16.9 0.1 0.009 15.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain DUF1496 PF07383.7 EPE35435.1 - 0.029 13.6 0.0 0.067 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1496) zinc_ribbon_5 PF13719.1 EPE35435.1 - 2 8.1 6.7 3.6 7.2 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EPE35435.1 - 7.8 6.2 8.1 4.3 7.1 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Pkinase PF00069.20 EPE35436.1 - 1.5e-07 30.8 0.0 2.9e-07 29.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 EPE35436.1 - 0.00021 20.3 0.0 0.00034 19.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE35436.1 - 0.00038 20.2 0.0 0.049 13.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EPE35436.1 - 0.0019 17.3 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 EPE35437.1 - 2.4e-17 62.0 23.6 4e-05 23.3 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat MraZ PF02381.13 EPE35437.1 - 0.16 11.7 0.0 27 4.6 0.0 2.5 2 0 0 2 2 2 0 MraZ protein Mg_trans_NIPA PF05653.9 EPE35438.1 - 3.7e-66 223.1 10.0 1.3e-62 211.5 3.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EPE35438.1 - 5.1e-05 23.4 0.8 5.1e-05 23.4 0.5 3.5 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EPE35438.1 - 0.0011 18.9 24.6 0.0018 18.2 1.7 4.1 3 1 1 4 4 4 2 EamA-like transporter family DUF914 PF06027.7 EPE35438.1 - 0.0015 17.4 0.2 0.0015 17.4 0.2 2.2 1 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) NicO PF03824.11 EPE35438.1 - 0.033 13.4 5.6 0.17 11.1 0.3 2.8 3 0 0 3 3 3 0 High-affinity nickel-transport protein DUF2101 PF09874.4 EPE35438.1 - 0.11 11.9 2.2 0.13 11.7 0.8 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2101) F-box PF00646.28 EPE35440.1 - 0.00021 20.8 0.5 0.00073 19.1 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EPE35440.1 - 0.00091 18.9 0.7 0.0029 17.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like zinc_ribbon_4 PF13717.1 EPE35440.1 - 0.032 13.9 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EPE35440.1 - 0.037 13.6 0.0 0.094 12.3 0.0 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Hydrolase_6 PF13344.1 EPE35441.1 - 5e-10 39.1 0.0 1.3e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase His_biosynth PF00977.16 EPE35442.1 - 6.6e-35 120.4 0.0 8e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EPE35442.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.1 EPE35443.1 - 5.3e-06 26.5 9.8 5.3e-06 26.5 6.8 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4602) CD99L2 PF12301.3 EPE35443.1 - 0.47 10.1 4.1 0.21 11.2 0.9 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 XPC-binding PF09280.6 EPE35447.1 - 3.6e-24 83.9 10.7 6.6e-24 83.1 7.4 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EPE35447.1 - 2.6e-18 65.1 0.8 4.1e-18 64.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EPE35447.1 - 8e-15 54.1 1.6 7.1e-09 35.2 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EPE35447.1 - 6.1e-08 32.2 0.5 1e-07 31.4 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EPE35447.1 - 0.024 14.5 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 EPE35447.1 - 0.064 13.7 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 MCM N-terminal domain DUF2407 PF10302.4 EPE35447.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CDC45 PF02724.9 EPE35448.1 - 0.0039 15.3 5.2 0.0065 14.5 3.6 1.3 1 0 0 1 1 1 1 CDC45-like protein eIF-6 PF01912.13 EPE35449.1 - 4.1e-83 277.3 2.0 5.4e-83 276.9 1.4 1.1 1 0 0 1 1 1 1 eIF-6 family Phage_holin_6 PF10746.4 EPE35449.1 - 0.08 12.6 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Phage holin family 6 Swi5 PF07061.6 EPE35450.1 - 1.7e-29 101.3 0.2 4.7e-29 100.0 0.1 1.8 1 0 0 1 1 1 1 Swi5 DUF1192 PF06698.6 EPE35450.1 - 0.045 13.5 2.4 0.15 11.8 1.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Tub_2 PF04525.7 EPE35451.1 - 3.3e-29 101.6 0.1 4e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 GFA PF04828.9 EPE35452.1 - 2.3e-20 72.2 1.0 2.6e-20 72.1 0.2 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF2652 PF10851.3 EPE35452.1 - 0.034 14.1 0.1 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) Auto_anti-p27 PF06677.7 EPE35452.1 - 0.085 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SVS_QK PF10578.4 EPE35452.1 - 0.16 12.3 0.2 0.38 11.1 0.2 1.5 1 0 0 1 1 1 0 Seminal vesicle protein repeat Glyco_hydro_35 PF01301.14 EPE35453.1 - 5.3e-75 252.7 7.7 8.2e-75 252.0 5.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EPE35453.1 - 2.3e-56 190.0 3.4 3.9e-56 189.3 2.4 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EPE35453.1 - 2.7e-49 166.0 7.8 8e-24 84.0 0.0 3.8 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EPE35453.1 - 3e-24 84.2 1.3 5.3e-24 83.4 0.1 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 EPE35453.1 - 8.3e-05 21.8 0.4 0.00061 19.0 0.5 2.2 1 1 1 2 2 2 1 Beta-galactosidase PTE PF02126.13 EPE35453.1 - 0.24 10.3 0.0 0.42 9.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotriesterase family Aminotran_3 PF00202.16 EPE35454.1 - 9.1e-98 327.2 0.0 1.1e-97 326.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EPE35454.1 - 0.0033 16.4 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II AT_hook PF02178.14 EPE35455.1 - 0.057 13.0 0.2 0.057 13.0 0.2 2.9 3 0 0 3 3 3 0 AT hook motif SET PF00856.23 EPE35457.1 - 1.5e-24 87.1 0.2 1.5e-24 87.1 0.1 2.9 2 2 0 2 2 2 1 SET domain SRI PF08236.6 EPE35457.1 - 1.9e-18 66.1 8.8 6.6e-18 64.4 6.1 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EPE35457.1 - 0.049 13.1 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 TFIIS helical bundle-like domain HTH_24 PF13412.1 EPE35457.1 - 0.086 12.2 0.5 0.18 11.2 0.3 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2431 PF10354.4 EPE35458.1 - 4.6e-40 137.3 0.0 5.8e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) ThiF PF00899.16 EPE35459.1 - 4.8e-14 52.3 0.0 9.3e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family Zn_clus PF00172.13 EPE35460.1 - 1e-09 38.1 5.9 2.2e-09 37.0 4.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE35460.1 - 0.0003 19.5 0.9 0.092 11.3 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pam17 PF08566.5 EPE35460.1 - 0.037 13.7 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Glyco_hydro_43 PF04616.9 EPE35461.1 - 4.4e-17 62.0 0.1 2.8e-16 59.4 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Methyltransf_23 PF13489.1 EPE35462.1 - 3.3e-16 59.4 0.0 4.9e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE35462.1 - 7.1e-08 32.1 0.0 5.3e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE35462.1 - 6e-07 29.8 0.0 1.5e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE35462.1 - 4.2e-06 27.3 0.0 4.5e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE35462.1 - 3.7e-05 24.1 0.0 0.0002 21.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE35462.1 - 0.00045 20.5 0.0 0.0013 19.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE35462.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EPE35462.1 - 0.02 14.8 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EPE35462.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EPE35462.1 - 0.086 11.8 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EPE35462.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EPE35462.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF2218 PF09981.4 EPE35464.1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) TFIIA PF03153.8 EPE35465.1 - 4.4e-75 253.9 46.7 2.4e-72 244.9 32.4 2.2 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.11 EPE35466.1 - 3.9e-33 114.6 25.1 3.9e-33 114.6 17.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.27 EPE35467.1 - 6e-24 83.0 19.2 3.4e-06 26.7 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EPE35467.1 - 3e-07 30.3 0.3 9.2e-05 22.2 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 EPE35467.1 - 0.086 12.5 2.4 1.7 8.3 0.2 3.1 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term Kelch_4 PF13418.1 EPE35468.1 - 3.8e-25 87.4 8.5 8.7e-09 35.0 0.0 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EPE35468.1 - 4.3e-23 80.7 6.6 4.2e-07 29.7 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EPE35468.1 - 2.5e-22 78.0 3.1 0.0001 22.3 0.0 5.0 3 1 1 4 4 4 4 Kelch motif Kelch_1 PF01344.20 EPE35468.1 - 2.7e-21 74.8 0.5 9.8e-06 25.0 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 EPE35468.1 - 1.3e-18 66.6 6.9 8.8e-07 28.9 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EPE35468.1 - 8.7e-18 63.3 6.0 0.00034 20.2 0.0 5.1 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 EPE35468.1 - 6.2e-11 42.2 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Rax2 PF12768.2 EPE35468.1 - 0.16 11.1 0.0 0.7 9.0 0.0 1.9 1 1 1 2 2 2 0 Cortical protein marker for cell polarity CPL PF08144.6 EPE35469.1 - 0.19 11.5 0.4 0.4 10.5 0.3 1.5 1 0 0 1 1 1 0 CPL (NUC119) domain Mito_carr PF00153.22 EPE35470.1 - 6e-64 211.8 2.9 9.1e-23 79.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GWT1 PF06423.7 EPE35472.1 - 3.7e-44 150.1 3.9 8.7e-44 148.9 2.7 1.7 1 0 0 1 1 1 1 GWT1 Pkinase PF00069.20 EPE35473.1 - 5.4e-63 212.5 0.0 8.8e-63 211.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE35473.1 - 9.4e-36 123.2 0.0 1.2e-30 106.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPE35473.1 - 2.2e-05 23.5 0.1 0.015 14.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EPE35473.1 - 0.0038 16.9 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPE35473.1 - 0.055 12.5 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPE35473.1 - 0.077 12.3 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Lactamase_B_3 PF13483.1 EPE35474.1 - 4e-05 23.3 0.0 7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DEAD PF00270.24 EPE35475.1 - 1.8e-29 102.4 0.0 5.6e-29 100.8 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE35475.1 - 2.1e-22 78.7 0.2 4.7e-22 77.6 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE35475.1 - 0.00024 21.0 0.0 0.00046 20.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Clr5 PF14420.1 EPE35476.1 - 7.3e-19 67.4 6.2 7.3e-19 67.4 4.3 2.8 3 0 0 3 3 3 1 Clr5 domain Sensor PF13796.1 EPE35476.1 - 1.3 8.5 3.0 3.1 7.3 2.1 1.6 1 0 0 1 1 1 0 Putative sensor FAD-oxidase_C PF02913.14 EPE35477.1 - 6.8e-57 192.6 0.2 1e-56 192.0 0.2 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EPE35477.1 - 1.9e-36 124.5 0.0 5.5e-36 123.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain SPRY PF00622.23 EPE35478.1 - 9.4e-05 22.4 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF605 PF04652.11 EPE35478.1 - 9.1 5.5 18.0 12 5.1 12.5 1.2 1 0 0 1 1 1 0 Vta1 like DUF1996 PF09362.5 EPE35480.1 - 7.1e-90 300.7 0.4 7.1e-90 300.7 0.2 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) TPP_enzyme_N PF02776.13 EPE35481.1 - 7.6e-28 97.1 0.1 1.4e-26 93.0 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EPE35481.1 - 4.5e-18 65.2 0.8 2.1e-17 63.1 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPE35481.1 - 4.6e-07 29.6 0.0 1.6e-05 24.6 0.0 3.2 3 1 1 4 4 4 1 Thiamine pyrophosphate enzyme, central domain Amidase PF01425.16 EPE35482.1 - 3.3e-88 296.4 0.0 6e-88 295.6 0.0 1.3 2 0 0 2 2 2 1 Amidase Formyl_trans_N PF00551.14 EPE35483.1 - 1.5e-36 125.6 0.1 1.9e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 EPE35483.1 - 3.9e-08 32.6 0.0 9.6e-08 31.3 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EPE35483.1 - 9.5e-05 22.0 0.0 0.00026 20.6 0.0 1.9 1 0 0 1 1 1 1 ACT domain Glyco_transf_25 PF01755.12 EPE35484.1 - 3.4e-12 46.4 0.0 7.7e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) eIF-5a PF01287.15 EPE35486.1 - 7.7e-05 22.5 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold TOBE_3 PF12857.2 EPE35486.1 - 0.11 12.4 1.5 18 5.2 0.1 2.9 1 1 1 2 2 2 0 TOBE-like domain E1-E2_ATPase PF00122.15 EPE35487.1 - 1e-61 207.9 8.9 2.7e-61 206.5 6.2 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPE35487.1 - 5.2e-31 107.5 7.8 5.2e-31 107.5 5.4 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPE35487.1 - 9.1e-27 94.8 0.0 1.6e-25 90.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPE35487.1 - 2.2e-15 55.8 0.0 6.8e-15 54.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EPE35487.1 - 8.4e-14 51.2 0.0 1.6e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPE35487.1 - 3.3e-12 46.9 0.0 1.2e-11 45.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPE35487.1 - 1.4e-05 24.8 2.8 5.1e-05 22.9 1.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tautomerase_3 PF14832.1 EPE35488.1 - 8.1e-33 113.3 0.0 9.1e-33 113.1 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme CFEM PF05730.6 EPE35489.1 - 1.1e-13 50.8 11.5 1.1e-13 50.8 8.0 1.7 2 0 0 2 2 2 1 CFEM domain MFS_1 PF07690.11 EPE35490.1 - 7.3e-34 117.0 23.7 7.3e-34 117.0 16.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE35490.1 - 5.7e-11 41.6 8.9 5.7e-11 41.6 6.2 3.6 2 2 2 4 4 4 1 Sugar (and other) transporter Gly-zipper_YMGG PF13441.1 EPE35490.1 - 6.5 6.3 8.7 1.3 8.6 1.3 2.9 2 0 0 2 2 2 0 YMGG-like Gly-zipper DUF2232 PF09991.4 EPE35491.1 - 0.046 12.7 0.0 0.063 12.2 0.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF1772 PF08592.6 EPE35491.1 - 0.14 11.8 3.0 1.9 8.1 2.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) adh_short_C2 PF13561.1 EPE35492.1 - 7.8e-18 65.1 0.0 1.1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE35492.1 - 1e-17 64.5 1.4 1.3e-17 64.2 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE35492.1 - 1.4e-06 28.1 2.1 6.8e-06 25.8 1.5 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPE35492.1 - 0.036 12.9 0.1 0.063 12.1 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DEAD PF00270.24 EPE35493.1 - 1.7e-18 66.6 0.0 5.1e-18 65.1 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE35493.1 - 2.3e-08 33.8 0.0 8.7e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EPE35493.1 - 8.3e-06 25.8 1.9 3.8e-05 23.7 0.1 3.0 3 0 0 3 3 3 1 Helix-hairpin-helix domain ResIII PF04851.10 EPE35493.1 - 0.00015 21.6 0.0 0.0006 19.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3717 PF12512.3 EPE35494.1 - 0.084 12.5 0.2 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) Astro_capsid PF03115.9 EPE35494.1 - 0.54 8.4 3.2 0.94 7.6 2.2 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF1510 PF07423.6 EPE35494.1 - 3.6 6.8 16.4 3.2 7.0 6.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DDE_3 PF13358.1 EPE35500.1 - 2.2e-09 37.2 1.4 1.4e-08 34.5 0.1 2.5 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EPE35500.1 - 1.3e-08 34.7 2.8 9.9e-08 31.9 0.4 2.8 2 1 1 3 3 3 1 Transposase HTH_38 PF13936.1 EPE35500.1 - 1.8e-05 24.2 0.0 5e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EPE35500.1 - 0.01 15.4 0.0 0.03 13.9 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4 PF04545.11 EPE35500.1 - 0.11 11.8 0.1 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_29 PF13551.1 EPE35500.1 - 0.17 12.0 3.6 0.36 11.0 0.2 3.0 3 1 0 3 3 3 0 Winged helix-turn helix SNF2_N PF00176.18 EPE35501.1 - 1.3e-27 96.3 0.0 2.3e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE35501.1 - 3.3e-11 42.8 0.0 1e-10 41.3 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE35501.1 - 8.5e-07 28.9 0.0 8.5e-07 28.9 0.0 2.6 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPE35501.1 - 8.4e-06 25.3 0.1 5.8e-05 22.6 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Nop14 PF04147.7 EPE35501.1 - 0.03 12.2 50.0 0.046 11.6 34.7 1.2 1 0 0 1 1 1 0 Nop14-like family PLRV_ORF5 PF01690.12 EPE35501.1 - 0.099 11.7 16.5 0.18 10.9 11.5 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mem_trans PF03547.13 EPE35501.1 - 0.1 10.8 0.1 0.11 10.7 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein SDA1 PF05285.7 EPE35501.1 - 0.26 10.5 46.6 0.44 9.7 32.3 1.3 1 0 0 1 1 1 0 SDA1 SAPS PF04499.10 EPE35501.1 - 0.4 9.2 16.2 0.2 10.2 9.6 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein BUD22 PF09073.5 EPE35501.1 - 1.3 8.0 46.5 2.1 7.3 32.3 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 EPE35501.1 - 4.7 5.1 41.8 7.9 4.3 29.0 1.3 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 EPE35501.1 - 5.7 6.0 33.5 8.8 5.4 23.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pilt PF15453.1 EPE35501.1 - 8.7 5.9 18.5 14 5.2 12.8 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions HAND PF09110.6 EPE35502.1 - 0.42 11.0 5.2 2.3 8.6 2.4 2.4 1 1 1 2 2 2 0 HAND Lectin_N PF03954.9 EPE35504.1 - 0.036 13.4 0.1 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain zf-HC5HC2H_2 PF13832.1 EPE35506.1 - 2.3e-21 75.8 1.5 2.3e-21 75.8 1.0 4.0 3 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EPE35506.1 - 1.3e-17 63.7 2.5 1.3e-17 63.7 1.8 4.7 4 1 0 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.13 EPE35506.1 - 1.5e-15 56.9 1.0 2.9e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 BAH domain PHD PF00628.24 EPE35506.1 - 2e-12 46.5 53.7 5.4e-06 26.0 5.5 6.4 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 EPE35506.1 - 3.7e-09 35.7 6.8 3.7e-09 35.7 4.7 5.7 6 0 0 6 6 6 2 PHD-finger Prok-RING_1 PF14446.1 EPE35506.1 - 0.00031 20.3 40.9 0.041 13.6 6.7 4.1 3 0 0 3 3 3 3 Prokaryotic RING finger family 1 C1_1 PF00130.17 EPE35506.1 - 0.0071 16.0 4.3 0.0071 16.0 3.0 5.6 5 1 1 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) YlaC PF10777.4 EPE35506.1 - 0.42 10.1 0.1 0.82 9.2 0.0 1.3 1 0 0 1 1 1 0 Inner membrane protein YlaC Git3 PF11710.3 EPE35507.1 - 5.6e-15 55.4 12.4 5.6e-15 55.4 8.6 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EPE35507.1 - 1.6e-08 34.2 0.1 1.6e-08 34.2 0.1 2.5 3 1 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Fip1 PF05182.8 EPE35507.1 - 0.059 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Fip1 motif DUF1600 PF07667.6 EPE35507.1 - 0.43 10.6 7.0 0.93 9.6 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1600) FMO-like PF00743.14 EPE35508.1 - 7.3e-32 110.2 0.0 8.7e-14 50.6 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EPE35508.1 - 7.7e-14 52.2 0.0 3.8e-12 46.7 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPE35508.1 - 1.1e-06 27.8 0.0 0.0021 17.0 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPE35508.1 - 1.8e-06 27.9 0.0 0.0046 16.8 0.0 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE35508.1 - 7.1e-05 22.6 0.0 0.094 12.4 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EPE35508.1 - 0.12 12.4 0.5 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain WD40 PF00400.27 EPE35509.1 - 1.1e-17 63.1 13.6 4e-06 26.4 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 EPE35509.1 - 0.01 15.0 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity RRM_5 PF13893.1 EPE35510.1 - 3.6e-09 36.3 0.0 5.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE35510.1 - 1.3e-07 31.1 0.0 2.5e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE35510.1 - 2.3e-05 24.2 0.0 4.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EPE35510.1 - 0.0003 20.4 1.2 0.00032 20.3 0.0 1.5 2 0 0 2 2 2 1 Calcipressin Autophagy_act_C PF03987.10 EPE35511.1 - 4.5e-12 45.9 0.1 8.1e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DUF3256 PF11644.3 EPE35512.1 - 0.048 13.1 0.3 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3256) Glyco_hydro_47 PF01532.15 EPE35513.1 - 9.6e-165 548.6 0.0 1.2e-164 548.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AA_permease PF00324.16 EPE35514.1 - 1.3e-141 472.2 37.9 1.7e-141 471.8 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE35514.1 - 5.8e-39 133.8 39.6 7.8e-39 133.4 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease His_Phos_2 PF00328.17 EPE35515.1 - 2.8e-13 49.9 0.5 5.5e-11 42.3 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) ADH_zinc_N PF00107.21 EPE35516.1 - 4.1e-12 45.7 0.0 2.8e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE35516.1 - 3.4e-07 29.9 0.3 2.6e-06 27.1 0.1 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF3445 PF11927.3 EPE35519.1 - 1.2e-70 237.8 0.0 3.8e-70 236.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3445) DUF3195 PF11424.3 EPE35519.1 - 0.2 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) Fungal_trans PF04082.13 EPE35520.1 - 5.5e-15 54.9 0.0 1.6e-14 53.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EPE35521.1 - 4.9e-14 51.8 9.4 5.1e-08 32.8 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EPE35521.1 - 2.4e-12 46.4 11.5 7.8e-06 25.9 1.6 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE35521.1 - 3.4e-11 42.6 11.8 3.8e-05 23.7 1.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPE35521.1 - 1.8e-07 31.0 1.8 0.029 14.5 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPE35521.1 - 3.1e-05 24.0 1.2 0.013 15.6 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 EPE35521.1 - 0.05 13.8 0.5 0.12 12.6 0.3 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.7 EPE35521.1 - 0.088 12.9 2.6 0.2 11.7 1.2 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.17 EPE35521.1 - 0.95 9.5 3.1 7.3 6.7 2.2 2.2 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 EPE35521.1 - 2.7 7.9 10.9 11 6.1 0.4 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger FMN_red PF03358.10 EPE35522.1 - 2.2e-11 43.4 0.0 2.7e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EPE35522.1 - 2.9e-11 43.5 0.0 4.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EPE35522.1 - 1.1e-06 28.2 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EPE35522.1 - 0.0067 16.4 0.0 0.084 12.8 0.0 2.1 1 1 0 1 1 1 1 Flavodoxin domain WW PF00397.21 EPE35523.1 - 8.6e-09 35.1 0.3 2.4e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 EPE35523.1 - 0.0015 17.2 0.3 0.0034 16.0 0.1 1.5 2 0 0 2 2 2 1 PhoD-like phosphatase AAA_22 PF13401.1 EPE35524.1 - 2.6e-13 50.2 0.1 5.1e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EPE35524.1 - 6.6e-12 45.7 0.1 2.1e-11 44.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPE35524.1 - 5.5e-11 42.7 0.2 1.6e-09 38.0 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.6 EPE35524.1 - 7e-07 28.8 0.0 8.7e-06 25.3 0.0 2.8 2 1 0 2 2 2 1 CDC6, C terminal TIP49 PF06068.8 EPE35524.1 - 0.00014 20.7 0.0 0.00024 19.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Arch_ATPase PF01637.13 EPE35524.1 - 0.00018 21.2 0.3 0.00046 19.9 0.2 1.7 1 1 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 EPE35524.1 - 0.00073 18.6 0.1 0.0014 17.7 0.1 1.4 1 0 0 1 1 1 1 KAP family P-loop domain DUF815 PF05673.8 EPE35524.1 - 0.0014 17.6 0.1 0.0036 16.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA12 PF10443.4 EPE35524.1 - 0.0018 16.8 0.0 0.003 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA12 protein NACHT PF05729.7 EPE35524.1 - 0.0019 17.8 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 EPE35524.1 - 0.0029 17.4 0.0 0.0066 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_32 PF13654.1 EPE35524.1 - 0.019 13.6 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPE35524.1 - 0.019 15.1 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase T2SE PF00437.15 EPE35524.1 - 0.038 12.9 0.1 0.07 12.0 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 EPE35524.1 - 0.07 13.6 0.1 0.19 12.2 0.0 1.7 2 0 0 2 2 1 0 Miro-like protein AAA_17 PF13207.1 EPE35524.1 - 0.082 13.7 0.1 0.2 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EPE35524.1 - 0.09 11.8 0.2 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus PMM PF03332.8 EPE35525.1 - 9.9e-90 299.9 0.1 8.7e-89 296.8 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.8 EPE35525.1 - 0.021 14.0 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Aminotran_4 PF01063.14 EPE35526.1 - 4.2e-22 78.7 0.0 1e-21 77.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class IV AATase PF07247.7 EPE35527.1 - 3.4e-24 85.2 0.0 7e-23 80.9 0.0 2.0 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EPE35527.1 - 4.3e-08 32.3 0.1 0.0008 18.3 0.0 2.6 2 1 0 2 2 2 2 Condensation domain NAPRTase PF04095.11 EPE35528.1 - 9.4e-51 172.4 0.1 2.9e-50 170.8 0.1 1.7 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Peptidase_M24 PF00557.19 EPE35528.1 - 0.072 12.6 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Metallopeptidase family M24 WD40 PF00400.27 EPE35529.1 - 9.6e-27 91.8 22.0 5.6e-10 38.7 0.1 9.9 10 1 0 10 10 10 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EPE35529.1 - 0.049 12.3 13.9 0.1 11.3 0.0 4.5 5 1 0 5 5 5 0 Nup133 N terminal like Abhydrolase_6 PF12697.2 EPE35530.1 - 1e-05 25.5 0.0 2.4e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EPE35530.1 - 0.021 14.4 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_5 PF12695.2 EPE35530.1 - 0.1 12.3 0.0 0.34 10.6 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 EPE35530.1 - 0.22 10.6 0.0 0.37 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) ADH_zinc_N PF00107.21 EPE35531.1 - 4e-30 104.0 0.3 1e-29 102.7 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE35531.1 - 1.2e-10 42.3 0.0 2.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE35531.1 - 1.7e-06 27.7 0.0 4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 EPE35531.1 - 0.0091 15.9 0.3 0.093 12.7 0.3 2.6 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Spt5-NGN PF03439.8 EPE35532.1 - 1.2e-23 82.6 0.1 2e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EPE35532.1 - 1.3e-21 76.9 10.3 1.3e-21 76.9 7.2 3.6 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 EPE35532.1 - 2.5e-21 76.3 68.3 3.8e-19 69.3 26.4 4.3 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 EPE35532.1 - 8.2e-07 28.5 18.7 0.00035 20.1 0.0 5.0 5 0 0 5 5 5 2 KOW motif DUF3506 PF12014.3 EPE35533.1 - 1.7e-50 170.3 0.0 1.1e-49 167.7 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EPE35533.1 - 2.5e-06 27.1 0.4 4.9e-06 26.1 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE35533.1 - 0.00021 20.8 0.1 0.0004 19.9 0.1 1.4 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 EPE35533.1 - 0.001 19.3 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF1769 PF08588.5 EPE35534.1 - 5.1e-29 99.9 1.8 5.7e-29 99.8 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) WD40 PF00400.27 EPE35535.1 - 3e-21 74.4 11.6 1.8e-08 33.9 0.0 5.9 7 0 0 7 7 7 4 WD domain, G-beta repeat CTP_transf_2 PF01467.21 EPE35536.1 - 0.0094 16.0 3.4 0.069 13.1 2.4 2.4 1 1 0 1 1 1 1 Cytidylyltransferase PRANC PF09372.5 EPE35537.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 PRANC domain CobT PF06213.7 EPE35537.1 - 4.1 6.4 12.4 6.2 5.8 8.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT adh_short_C2 PF13561.1 EPE35538.1 - 1.4e-22 80.6 0.0 1.7e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE35538.1 - 4.1e-14 52.8 0.3 4.1e-14 52.8 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE35538.1 - 3.5e-06 26.8 0.1 5e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE35538.1 - 0.053 12.9 0.1 0.083 12.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3987 PF13148.1 EPE35539.1 - 0.00067 18.3 7.9 0.003 16.2 0.0 2.7 1 1 0 2 2 2 1 Protein of unknown function (DUF3987) Cob_adeno_trans PF01923.13 EPE35539.1 - 0.022 14.5 3.5 0.055 13.2 1.7 2.0 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DivIC PF04977.10 EPE35539.1 - 0.68 9.4 8.2 16 5.0 0.0 2.7 2 0 0 2 2 2 0 Septum formation initiator AcylCoA_dehyd_C PF12186.3 EPE35539.1 - 1.4 8.8 5.4 4 7.3 1.1 2.8 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase C terminal DUF4140 PF13600.1 EPE35539.1 - 7.1 7.1 10.5 26 5.3 3.5 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 EPE35539.1 - 8.8 4.0 11.1 0.97 7.2 2.8 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EPE35539.1 - 9 5.2 12.5 2.3 7.2 5.9 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 XhlA PF10779.4 EPE35539.1 - 9.5 6.2 10.8 11 6.0 5.2 2.5 1 1 1 2 2 2 0 Haemolysin XhlA DUF1748 PF08520.5 EPE35540.1 - 9.6e-33 111.6 0.1 1.9e-32 110.6 0.1 1.5 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1748) PK PF00224.16 EPE35541.1 - 4.6e-168 558.2 9.0 5.7e-168 557.9 6.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EPE35541.1 - 2.7e-30 104.3 0.0 1.1e-29 102.3 0.0 2.1 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EPE35541.1 - 0.00019 20.4 0.9 0.00076 18.4 0.6 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EPE35541.1 - 0.013 14.3 0.1 0.12 11.2 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Abhydrolase_6 PF12697.2 EPE35542.1 - 1.9e-05 24.6 0.0 0.00038 20.4 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE35542.1 - 2.9e-05 23.8 0.0 0.00012 21.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Syntaxin-6_N PF09177.6 EPE35542.1 - 0.011 16.0 0.6 0.023 15.0 0.4 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal SIP PF04954.8 EPE35542.1 - 0.058 13.7 0.1 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Siderophore-interacting protein MRP-S24 PF14955.1 EPE35542.1 - 0.096 12.5 0.2 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 Abhydrolase_1 PF00561.15 EPE35542.1 - 0.2 11.1 1.2 8.6 5.8 0.0 3.0 3 1 0 3 3 3 0 alpha/beta hydrolase fold Kelch_4 PF13418.1 EPE35543.1 - 9.9e-17 60.4 0.0 1.8e-05 24.4 0.0 5.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EPE35543.1 - 3.6e-16 58.8 4.1 4.7e-10 39.3 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EPE35543.1 - 2.6e-08 33.2 0.0 0.2 11.2 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EPE35543.1 - 3.4e-08 33.2 7.2 0.0026 17.6 0.0 4.2 4 1 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 EPE35543.1 - 1.1e-07 31.6 4.8 0.2 11.8 0.6 5.2 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EPE35543.1 - 9.8e-07 28.3 2.4 0.0036 17.0 0.0 4.6 4 1 0 4 4 4 1 Kelch motif BTB PF00651.26 EPE35543.1 - 0.0053 16.7 0.0 0.22 11.5 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Prp31_C PF09785.4 EPE35544.1 - 6e-43 146.2 1.4 1.2e-42 145.1 0.9 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EPE35544.1 - 5.2e-40 136.1 0.0 9e-40 135.4 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EPE35544.1 - 3.1e-21 74.9 0.1 5.1e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain HAT PF02184.11 EPE35545.1 - 6.7e-28 96.1 62.6 1.9e-14 53.0 1.4 13.7 14 0 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EPE35545.1 - 1.3e-22 78.2 23.9 0.00065 20.1 0.0 11.6 7 4 5 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPE35545.1 - 2.8e-21 75.5 4.7 3.6e-05 24.0 0.0 7.9 7 1 2 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EPE35545.1 - 1.7e-18 66.7 15.9 0.00038 21.0 0.0 8.3 9 0 0 9 9 8 4 Tetratricopeptide repeat Suf PF05843.9 EPE35545.1 - 4e-14 53.0 18.8 0.0004 20.1 0.3 5.8 3 2 1 6 6 6 4 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EPE35545.1 - 1.4e-09 37.1 23.1 0.45 10.5 0.0 10.0 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPE35545.1 - 1.8e-08 33.8 11.3 0.4 10.3 0.0 6.7 6 1 1 7 7 6 3 TPR repeat TPR_17 PF13431.1 EPE35545.1 - 7e-08 32.0 3.5 0.18 12.1 0.0 5.5 5 0 0 5 5 4 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EPE35545.1 - 4.2e-07 29.6 22.8 0.0064 16.2 0.8 7.2 4 2 3 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.1 EPE35545.1 - 2.8e-06 27.1 24.4 0.15 12.0 0.0 8.6 8 2 1 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPE35545.1 - 0.00035 20.1 16.4 11 6.0 0.0 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPE35545.1 - 0.0009 18.8 12.5 6.7 6.7 0.1 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPE35545.1 - 0.0014 18.8 22.9 27 5.5 0.0 9.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_15 PF13429.1 EPE35545.1 - 0.0018 17.3 23.4 0.058 12.4 0.4 6.0 3 2 1 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EPE35545.1 - 0.012 14.4 32.5 0.19 10.5 0.1 7.2 3 3 4 8 8 8 0 NRDE-2, necessary for RNA interference TPR_1 PF00515.23 EPE35545.1 - 0.016 14.8 6.5 47 3.8 0.0 6.3 5 0 0 5 5 5 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.5 EPE35545.1 - 0.91 9.6 7.3 10 6.3 0.0 4.4 4 0 0 4 4 4 0 c-SKI Smad4 binding domain PBP1_TM PF14812.1 EPE35545.1 - 2.7 8.3 8.9 4.1 7.7 0.5 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fis1_TPR_C PF14853.1 EPE35545.1 - 2.9 7.8 13.7 42 4.1 1.2 6.4 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat zf-C2H2_4 PF13894.1 EPE35547.1 - 2.8e-05 24.1 6.4 0.0016 18.6 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE35547.1 - 6.9e-05 22.9 10.2 0.0094 16.2 1.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPE35547.1 - 0.0098 16.1 2.3 0.0098 16.1 1.6 3.2 3 0 0 3 3 3 1 Zinc-finger double domain MTP18 PF10558.4 EPE35547.1 - 0.055 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) zf-TRAF PF02176.13 EPE35547.1 - 0.49 10.8 3.7 1.3 9.4 0.5 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger zf-met PF12874.2 EPE35547.1 - 1.4 9.2 13.4 0.49 10.6 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type XFP_N PF09364.5 EPE35548.1 - 3.1e-143 476.9 0.9 2.8e-101 338.8 0.1 2.2 1 1 1 2 2 2 2 XFP N-terminal domain XFP PF03894.10 EPE35548.1 - 1.4e-69 233.2 0.0 2e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EPE35548.1 - 3.7e-69 232.2 0.0 6.6e-69 231.4 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 EPE35548.1 - 0.0025 17.4 0.1 0.0059 16.1 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Acetate_kinase PF00871.12 EPE35549.1 - 6.8e-91 304.6 0.0 8.5e-91 304.3 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family GST_N_3 PF13417.1 EPE35550.1 - 2.2e-21 75.8 0.0 5.3e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPE35550.1 - 4.9e-13 48.8 0.0 1.3e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPE35550.1 - 2.9e-05 24.1 0.0 0.00011 22.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE35550.1 - 0.00095 19.0 0.2 0.0022 17.8 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EPE35550.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin PUL PF08324.6 EPE35552.1 - 5.1e-45 153.3 2.0 6.6e-45 152.9 1.4 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EPE35552.1 - 4.9e-44 149.0 0.9 2e-43 147.0 0.1 2.1 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EPE35552.1 - 2.2e-36 122.4 17.8 2.6e-05 23.9 0.0 8.1 8 1 0 8 8 8 7 WD domain, G-beta repeat XPG_I PF00867.13 EPE35552.1 - 0.1 12.6 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 XPG I-region Peptidase_S41 PF03572.13 EPE35553.1 - 1.5e-07 30.9 0.0 4.3e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 DUF290 PF01060.18 EPE35553.1 - 0.026 14.5 0.0 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Transthyretin-like family TSKS PF15358.1 EPE35553.1 - 1.1 7.3 2.4 1.7 6.7 1.6 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate HET PF06985.6 EPE35554.1 - 3.7e-26 91.9 0.2 7.8e-26 90.8 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FMO-like PF00743.14 EPE35555.1 - 5.5e-32 110.6 0.0 1.6e-17 62.9 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EPE35555.1 - 3.4e-16 59.9 0.1 6.2e-15 55.7 0.0 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE35555.1 - 4e-10 39.9 0.0 1.7e-08 34.5 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE35555.1 - 1.6e-09 37.1 0.3 1.2e-07 30.9 0.3 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE35555.1 - 2.8e-09 36.8 0.0 1.3e-08 34.7 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPE35555.1 - 5.8e-08 32.6 1.0 2.4e-05 24.1 0.2 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPE35555.1 - 4.6e-05 22.5 0.1 0.0087 15.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EPE35555.1 - 0.00011 22.3 1.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.19 EPE35555.1 - 0.00031 19.9 0.0 0.0015 17.6 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EPE35555.1 - 0.00057 19.0 1.2 0.0025 16.9 0.3 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EPE35555.1 - 0.0006 20.1 4.8 0.0014 18.9 0.8 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPE35555.1 - 0.00088 17.8 0.8 0.0014 17.1 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EPE35555.1 - 0.0013 17.8 0.1 0.0024 16.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EPE35555.1 - 0.0016 17.3 0.6 0.0026 16.6 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EPE35555.1 - 0.0073 16.0 0.3 0.32 10.7 0.3 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 EPE35555.1 - 0.0095 15.0 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 EPE35555.1 - 0.014 14.7 0.0 0.072 12.5 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 EPE35555.1 - 0.017 14.5 0.9 0.024 13.9 0.1 1.6 2 0 0 2 2 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EPE35555.1 - 0.023 14.5 0.1 0.057 13.2 0.0 1.7 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EPE35555.1 - 0.037 13.6 2.2 0.045 13.4 0.5 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EPE35555.1 - 0.037 13.3 0.3 0.1 11.9 0.2 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain OprF PF05736.6 EPE35555.1 - 0.047 13.2 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 OprF membrane domain NAD_binding_7 PF13241.1 EPE35555.1 - 0.049 13.8 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 EPE35555.1 - 0.087 11.6 1.0 0.16 10.7 0.7 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EPE35555.1 - 0.16 10.5 1.4 0.24 10.0 0.9 1.2 1 0 0 1 1 1 0 Tryptophan halogenase p450 PF00067.17 EPE35556.1 - 3e-51 174.3 0.0 3.8e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.15 EPE35557.1 - 7.9e-67 225.6 0.0 9.8e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1510 PF07423.6 EPE35558.1 - 8.1 5.7 22.1 7.5 5.8 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) NmrA PF05368.8 EPE35559.1 - 4.9e-07 29.2 0.1 7.4e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE35559.1 - 8.4e-06 25.9 0.1 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EPE35559.1 - 1.5e-05 24.1 0.1 2.5e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EPE35559.1 - 7.5e-05 23.0 0.1 0.00018 21.8 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EPE35559.1 - 0.00044 20.2 0.1 0.00086 19.2 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 EPE35559.1 - 0.0006 18.8 0.0 0.00094 18.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_Gly3P_dh_N PF01210.18 EPE35559.1 - 0.003 17.2 0.4 0.01 15.6 0.0 1.9 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EPE35559.1 - 0.0052 17.1 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DXP_reductoisom PF02670.11 EPE35559.1 - 0.0081 16.6 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Epimerase PF01370.16 EPE35559.1 - 0.013 14.9 0.3 0.041 13.3 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE35559.1 - 0.034 12.8 0.0 0.054 12.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EPE35559.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AAA_25 PF13481.1 EPE35560.1 - 0.0001 21.7 0.1 0.00025 20.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EPE35560.1 - 0.00011 21.6 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE35560.1 - 0.00023 20.8 0.0 0.00059 19.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPE35560.1 - 0.00042 19.9 0.1 0.00078 19.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPE35560.1 - 0.00071 19.2 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EPE35560.1 - 0.0012 18.3 0.1 0.0023 17.3 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 EPE35560.1 - 0.014 15.7 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EPE35560.1 - 0.03 13.8 0.1 0.083 12.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD-helicase PF00580.16 EPE35560.1 - 0.043 13.1 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain MobB PF03205.9 EPE35560.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EPE35560.1 - 0.051 13.8 0.1 0.18 12.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EPE35560.1 - 0.052 13.5 0.1 0.15 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.1 EPE35560.1 - 0.054 13.4 1.6 0.17 11.8 1.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EPE35560.1 - 0.055 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 EPE35560.1 - 0.063 13.6 0.1 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EPE35560.1 - 0.097 12.3 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain PIF1 PF05970.9 EPE35560.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase HET PF06985.6 EPE35562.1 - 6.9e-24 84.5 0.0 1.5e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pec_lyase_C PF00544.14 EPE35563.1 - 3.2e-42 144.3 5.7 7e-42 143.1 3.9 1.5 1 1 0 1 1 1 1 Pectate lyase Glyco_hydro_11 PF00457.12 EPE35564.1 - 7.8e-55 185.0 18.6 1.1e-54 184.6 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 PC-Esterase PF13839.1 EPE35564.1 - 0.084 12.6 0.2 0.098 12.4 0.1 1.1 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Fib_alpha PF08702.5 EPE35566.1 - 0.0011 19.1 15.0 0.17 11.9 0.0 4.4 4 1 1 5 5 5 2 Fibrinogen alpha/beta chain family CRA_rpt PF07046.6 EPE35566.1 - 0.086 12.8 0.7 0.21 11.6 0.5 1.7 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat TMF_DNA_bd PF12329.3 EPE35566.1 - 0.53 10.1 22.8 0.63 9.8 1.7 5.2 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 EPE35566.1 - 2 8.2 11.4 0.32 10.8 0.4 3.6 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc24 PF08286.6 EPE35566.1 - 2.3 7.9 11.8 2.8 7.6 0.2 3.8 4 0 0 4 4 4 0 Spc24 subunit of Ndc80 MscS_porin PF12795.2 EPE35567.1 - 0.034 13.4 2.9 0.23 10.7 0.3 2.5 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain CENP-Q PF13094.1 EPE35568.1 - 0.022 14.7 2.6 0.022 14.7 1.8 3.9 1 1 4 5 5 5 0 CENP-Q, a CENPA-CAD centromere complex subunit Serine_rich PF08824.5 EPE35568.1 - 0.39 10.4 7.4 6 6.5 1.3 2.8 1 1 0 2 2 2 0 Serine rich protein interaction domain Reo_sigmaC PF04582.7 EPE35568.1 - 0.69 9.0 8.3 0.084 12.0 0.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1993 PF09351.5 EPE35568.1 - 1.1 9.1 5.4 1 9.2 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) IncA PF04156.9 EPE35568.1 - 9.3 5.7 26.4 0.052 13.1 7.7 2.7 1 1 1 2 2 2 0 IncA protein MFS_1 PF07690.11 EPE35570.1 - 6.8e-41 140.1 41.2 6.8e-41 140.1 28.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE35570.1 - 2.4e-10 39.6 10.2 2.4e-10 39.6 7.1 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EPE35570.1 - 2.9e-08 32.4 1.6 4.4e-08 31.7 1.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) E1-E2_ATPase PF00122.15 EPE35570.1 - 0.3 10.1 1.7 0.38 9.7 0.0 2.0 2 0 0 2 2 2 0 E1-E2 ATPase Zn_clus PF00172.13 EPE35571.1 - 0.00017 21.4 9.0 0.00034 20.4 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE35571.1 - 0.00018 20.5 0.2 0.0004 19.3 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.18 EPE35572.1 - 3.8e-08 33.3 0.0 9.2e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family ketoacyl-synt PF00109.21 EPE35573.1 - 1.4e-64 218.0 0.1 4.1e-64 216.5 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPE35573.1 - 1.1e-52 179.3 0.0 1.8e-52 178.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EPE35573.1 - 2.6e-36 124.0 0.5 8.1e-36 122.4 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EPE35573.1 - 2.9e-14 53.8 0.1 1.3e-13 51.7 0.0 2.2 3 0 0 3 3 3 1 Thioesterase domain PP-binding PF00550.20 EPE35573.1 - 1.3e-10 41.4 0.6 3.1e-10 40.1 0.4 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EPE35573.1 - 2.5e-06 27.2 0.1 0.092 12.4 0.0 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE35573.1 - 4.1e-05 23.5 9.5 0.026 14.3 0.0 3.8 3 1 0 3 3 3 2 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 EPE35574.1 - 2.4e-69 233.6 0.1 3.9e-69 232.9 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EPE35574.1 - 3.8e-62 209.1 0.0 1.7e-61 207.0 0.0 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EPE35574.1 - 5.9e-55 186.8 0.1 9.7e-55 186.1 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EPE35574.1 - 1.5e-46 158.3 0.4 5.8e-46 156.4 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EPE35574.1 - 4.9e-43 147.3 0.0 9.7e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EPE35574.1 - 1.8e-38 131.0 0.1 1.6e-37 127.9 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EPE35574.1 - 6.2e-21 74.3 0.0 1.7e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPE35574.1 - 3.8e-12 47.2 0.0 1.3e-11 45.4 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EPE35574.1 - 1.6e-06 28.2 0.0 4.6e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EPE35574.1 - 0.00017 20.6 0.1 0.00017 20.6 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_N PF08240.7 EPE35574.1 - 0.0016 18.1 0.2 0.004 16.8 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TPR_11 PF13414.1 EPE35576.1 - 1.1e-12 47.3 0.0 1.7e-08 34.0 0.0 2.5 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EPE35576.1 - 2.1e-08 33.4 2.6 0.00034 20.3 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPE35576.1 - 6.1e-07 28.7 0.8 0.028 14.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPE35576.1 - 0.0002 21.2 0.1 0.064 13.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPE35576.1 - 0.00045 19.8 0.1 0.045 13.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPE35576.1 - 0.0018 18.5 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPE35576.1 - 0.0086 16.7 0.0 0.16 12.6 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE35576.1 - 0.0088 16.5 0.2 0.58 10.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE35576.1 - 0.11 12.3 0.0 4.2 7.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Takusan PF04822.8 EPE35577.1 - 0.14 11.9 3.2 3.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Takusan APH PF01636.18 EPE35578.1 - 1.2e-08 35.0 0.0 2.5e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE35578.1 - 8.5e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EPE35578.1 - 0.061 12.6 0.0 4 6.7 0.0 2.3 2 0 0 2 2 2 0 RIO1 family DUF3717 PF12512.3 EPE35579.1 - 0.12 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) LysM PF01476.15 EPE35580.1 - 1e-05 25.2 0.0 0.00042 20.1 0.0 2.3 2 0 0 2 2 2 2 LysM domain MUG113 PF13455.1 EPE35582.1 - 6.1e-31 106.7 0.4 1.5e-30 105.5 0.3 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EPE35582.1 - 3e-22 78.8 0.1 9.4e-22 77.3 0.0 1.8 1 0 0 1 1 1 1 T5orf172 domain PGAP1 PF07819.8 EPE35584.1 - 3e-06 26.9 0.0 6.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein HeLo PF14479.1 EPE35584.1 - 0.00011 22.0 0.2 0.00025 20.8 0.1 1.5 1 1 0 1 1 1 1 Prion-inhibition and propagation DUF676 PF05057.9 EPE35584.1 - 0.00063 19.1 0.1 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPE35584.1 - 0.0018 18.1 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF726 PF05277.7 EPE35584.1 - 0.029 13.2 0.1 0.08 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF726) DUF829 PF05705.9 EPE35584.1 - 0.048 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_5 PF12695.2 EPE35584.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 EPE35584.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Pkinase PF00069.20 EPE35585.1 - 2.3e-26 92.5 0.0 3.9e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE35585.1 - 3.3e-19 68.9 0.0 5.9e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.1 EPE35585.1 - 4.2e-13 49.0 5.0 3.3e-05 23.7 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPE35585.1 - 4.9e-13 48.5 0.1 1.3e-05 24.9 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat APH PF01636.18 EPE35585.1 - 0.00025 20.8 0.0 0.00062 19.5 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_7 PF13176.1 EPE35585.1 - 0.00096 18.7 0.4 25 4.9 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Kdo PF06293.9 EPE35585.1 - 0.00098 18.2 0.0 0.0023 17.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_14 PF13428.1 EPE35585.1 - 0.01 16.4 0.3 25 5.8 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.15 EPE35585.1 - 0.026 14.4 0.4 73 3.6 0.0 4.2 5 0 0 5 5 3 0 PPR repeat TPR_2 PF07719.12 EPE35585.1 - 0.046 13.6 0.9 9.1 6.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 EPE35585.1 - 0.065 13.9 0.1 0.41 11.3 0.0 2.4 1 0 0 1 1 1 0 Sel1 repeat HRXXH PF13933.1 EPE35587.1 - 1.1e-09 38.1 0.5 1.5e-09 37.6 0.3 1.2 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M35 PF02102.10 EPE35587.1 - 0.025 13.2 4.4 0.68 8.5 0.6 2.6 2 1 0 2 2 2 0 Deuterolysin metalloprotease (M35) family GP46 PF07409.7 EPE35587.1 - 0.036 13.3 0.5 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 Phage protein GP46 HRXXH PF13933.1 EPE35588.1 - 0.0015 17.9 3.4 0.0027 17.1 2.4 1.5 1 1 0 1 1 1 1 Putative peptidase family Sushi_2 PF09014.5 EPE35588.1 - 0.044 13.5 0.1 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain Bac_luciferase PF00296.15 EPE35589.1 - 6.9e-57 192.8 0.0 9.1e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Cullin PF00888.17 EPE35591.1 - 3.8e-109 365.8 0.1 5.1e-109 365.4 0.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EPE35591.1 - 1.8e-27 94.9 1.1 7.2e-27 93.0 0.8 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain MarR_2 PF12802.2 EPE35591.1 - 0.046 13.3 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 MarR family Pkinase PF00069.20 EPE35592.1 - 2.1e-15 56.5 0.0 2.4e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE35592.1 - 3.6e-05 22.9 0.0 4.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPE35592.1 - 0.00067 18.7 0.1 0.38 9.7 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EPE35592.1 - 0.031 13.0 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EPE35592.1 - 0.11 12.2 0.1 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3414 PF11894.3 EPE35593.1 - 0 1327.5 5.3 0 1327.2 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) PI3_PI4_kinase PF00454.22 EPE35594.1 - 1.1e-46 159.2 0.0 2.2e-46 158.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EPE35594.1 - 1.2e-24 86.7 2.4 1.4e-24 86.5 0.1 2.5 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EPE35594.1 - 1.1e-10 40.7 0.1 2.9e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 FATC domain Imm48 PF15587.1 EPE35594.1 - 0.05 12.9 0.0 7.1 5.9 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 48 Ferritin_2 PF13668.1 EPE35595.1 - 2.3e-39 134.4 1.9 3.5e-39 133.8 1.3 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF4565 PF15127.1 EPE35595.1 - 0.086 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4565) Spb1_C PF07780.7 EPE35596.1 - 1.1e-73 247.3 16.0 1.1e-73 247.3 11.1 3.7 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EPE35596.1 - 7.5e-58 194.5 10.0 7.5e-58 194.5 6.9 4.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EPE35596.1 - 9.9e-55 185.3 0.0 2.2e-54 184.2 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EPE35596.1 - 0.006 17.1 0.1 1.3 9.6 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain WD40 PF00400.27 EPE35597.1 - 8.8e-21 72.9 6.1 0.00014 21.5 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EPE35597.1 - 9.5e-06 24.0 2.5 0.00087 17.5 0.3 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Glyco_hydro_16 PF00722.16 EPE35598.1 - 2.6e-15 56.2 2.3 3.9e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.13 EPE35599.1 - 3.7e-16 58.7 2.3 7e-16 57.8 1.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EPE35599.1 - 8.2e-09 35.3 12.0 1.7e-05 24.8 4.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPE35599.1 - 6.5e-05 22.9 13.0 0.0041 17.3 3.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE35599.1 - 0.00027 21.0 14.7 0.035 14.4 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type RasGEF PF00617.14 EPE35600.1 - 2e-63 213.5 0.1 3.3e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EPE35600.1 - 1.6e-24 85.9 1.9 3e-24 85.1 0.2 2.3 2 1 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 EPE35600.1 - 3.8e-15 54.9 0.1 7.5e-15 54.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPE35600.1 - 9.7e-14 50.6 0.2 2.5e-13 49.3 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPE35600.1 - 1.1e-12 47.1 0.1 2.2e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EPE35600.1 - 3.9e-05 23.4 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 WW domain HTH_Tnp_Tc3_2 PF01498.13 EPE35602.1 - 1.1e-06 28.5 0.7 2.2e-06 27.6 0.5 1.5 1 0 0 1 1 1 1 Transposase DNA_pol_A PF00476.15 EPE35603.1 - 1.1e-102 343.5 0.0 1.8e-102 342.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EPE35603.1 - 0.0026 17.2 0.2 0.034 13.6 0.1 2.3 1 1 0 1 1 1 1 3'-5' exonuclease CTV_P6 PF06706.6 EPE35603.1 - 0.23 10.9 0.1 0.45 10.0 0.0 1.5 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein zf-C3HC4_3 PF13920.1 EPE35604.1 - 9.1e-11 41.2 11.3 1.4e-10 40.6 7.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE35604.1 - 1.1e-08 34.7 13.1 1.8e-08 34.0 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE35604.1 - 4.6e-08 32.9 13.4 7.1e-08 32.3 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE35604.1 - 4e-07 29.6 13.2 6.2e-07 29.0 9.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE35604.1 - 2.6e-06 26.9 13.6 4.1e-06 26.3 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EPE35604.1 - 0.0032 16.9 8.3 0.0059 16.1 5.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EPE35604.1 - 0.0032 17.0 10.0 0.006 16.1 6.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EPE35604.1 - 0.02 14.6 9.8 0.023 14.3 4.9 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 EPE35604.1 - 0.035 13.9 4.7 0.062 13.0 3.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EPE35604.1 - 0.043 13.6 11.0 0.087 12.7 7.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EPE35604.1 - 0.098 12.7 5.6 0.2 11.7 3.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger AvrE PF11725.3 EPE35604.1 - 0.48 7.3 7.5 0.6 7.0 5.2 1.0 1 0 0 1 1 1 0 Pathogenicity factor VWC PF00093.13 EPE35604.1 - 1.2 9.2 8.0 2 8.6 5.6 1.3 1 0 0 1 1 1 0 von Willebrand factor type C domain UPF0052 PF01933.13 EPE35605.1 - 3e-52 177.8 0.0 3.9e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 RRM_6 PF14259.1 EPE35607.1 - 1.3e-10 41.0 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE35607.1 - 4.3e-09 35.8 0.1 1e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE35607.1 - 2e-05 24.3 0.0 4.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RR_TM4-6 PF06459.7 EPE35607.1 - 0.93 9.3 10.2 1.6 8.5 7.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tom37_C PF11801.3 EPE35607.1 - 3.4 7.4 6.4 5.3 6.8 4.5 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Cupin_8 PF13621.1 EPE35608.1 - 2.2e-54 184.5 0.0 2.8e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EPE35608.1 - 0.00044 19.5 0.0 0.0008 18.7 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EPE35608.1 - 0.067 13.4 0.0 0.2 11.9 0.0 2.0 1 1 0 1 1 1 0 JmjC domain, hydroxylase 2OG-FeII_Oxy_5 PF13759.1 EPE35608.1 - 0.087 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase WSC PF01822.14 EPE35609.1 - 4.1e-37 125.9 23.0 1.1e-20 73.3 5.4 5.0 3 1 0 3 3 3 2 WSC domain peroxidase PF00141.18 EPE35609.1 - 1.1e-18 67.5 0.0 2.5e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Peroxidase S1 PF00575.18 EPE35610.1 - 1.2e-94 310.4 33.8 1.6e-15 56.9 1.3 13.2 12 1 1 13 13 13 11 S1 RNA binding domain Suf PF05843.9 EPE35610.1 - 2.7e-09 37.1 0.0 0.062 13.0 0.0 4.1 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EPE35610.1 - 9.5e-08 32.0 0.0 0.12 13.1 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPE35610.1 - 3.9e-06 27.1 0.0 1.1 9.6 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPE35610.1 - 1.4e-05 25.5 0.0 0.053 14.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPE35610.1 - 0.00018 21.0 0.0 0.011 15.3 0.0 2.4 2 0 0 2 2 2 1 TPR repeat S1_2 PF13509.1 EPE35610.1 - 0.0009 19.1 0.1 2.1 8.2 0.0 4.6 4 0 0 4 4 4 1 S1 domain NRDE-2 PF08424.5 EPE35610.1 - 0.025 13.4 1.9 0.17 10.6 0.9 2.8 1 1 1 2 2 2 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.1 EPE35610.1 - 0.075 13.5 0.1 5.3 7.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Nop14 PF04147.7 EPE35610.1 - 1.5 6.6 25.5 3.5 5.4 17.7 1.5 1 0 0 1 1 1 0 Nop14-like family DUF2088 PF09861.4 EPE35611.1 - 0.0025 16.8 0.0 0.012 14.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2088) DOT1 PF08123.8 EPE35612.1 - 3.8e-75 251.6 0.0 6.1e-75 251.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 EPE35612.1 - 8.7e-05 22.1 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE35612.1 - 0.00017 21.5 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE35612.1 - 0.0046 17.5 0.7 0.019 15.5 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain ATG16 PF08614.6 EPE35613.1 - 3.4e-41 141.2 18.3 3.9e-41 141.0 12.7 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 EPE35613.1 - 0.0003 20.2 9.4 0.00056 19.4 6.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DEAD_assoc PF08494.6 EPE35613.1 - 0.0091 15.7 0.8 0.011 15.4 0.5 1.2 1 0 0 1 1 1 1 DEAD/H associated Macoilin PF09726.4 EPE35613.1 - 0.17 10.0 12.1 0.19 9.9 8.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 EPE35613.1 - 0.22 10.4 8.5 0.3 9.9 5.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 EPE35613.1 - 0.25 10.4 2.2 0.4 9.7 1.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 EPE35613.1 - 0.32 10.5 18.1 1.8 8.0 2.1 2.4 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 EPE35613.1 - 0.43 9.7 19.2 2.8 7.0 11.4 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Uds1 PF15456.1 EPE35613.1 - 0.57 10.1 10.3 1.3 9.0 7.2 1.6 1 0 0 1 1 1 0 Up-regulated During Septation V_ATPase_I PF01496.14 EPE35613.1 - 0.81 7.4 6.0 1.1 7.0 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.6 EPE35613.1 - 1.3 8.9 3.9 2 8.3 2.3 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YkyA PF10368.4 EPE35613.1 - 1.5 8.1 15.7 0.099 11.9 7.0 1.7 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Rho_Binding PF08912.6 EPE35613.1 - 2.5 8.4 12.9 2.6 8.3 0.5 2.9 1 1 1 2 2 2 0 Rho Binding APG6 PF04111.7 EPE35613.1 - 2.8 6.9 16.4 0.16 10.9 7.2 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 zf-C4H2 PF10146.4 EPE35613.1 - 6.9 6.6 12.3 1.4 8.8 5.9 1.7 1 1 1 2 2 2 0 Zinc finger-containing protein Ras PF00071.17 EPE35614.1 - 1.7e-56 190.1 0.1 2e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE35614.1 - 9e-19 68.1 0.0 1.3e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE35614.1 - 1.1e-12 47.4 0.0 1.4e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EPE35614.1 - 3e-07 30.4 0.0 4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EPE35614.1 - 6.8e-07 28.6 0.0 8.3e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPE35614.1 - 2e-06 27.3 0.0 7.3e-05 22.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EPE35614.1 - 0.00087 19.4 0.0 0.0013 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPE35614.1 - 0.0012 18.1 0.1 0.0022 17.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 EPE35614.1 - 0.0035 17.0 0.0 0.018 14.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EPE35614.1 - 0.0047 16.5 0.2 0.0082 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EPE35614.1 - 0.0057 16.1 0.1 0.097 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EPE35614.1 - 0.0065 16.1 0.2 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 EPE35614.1 - 0.0078 15.6 0.2 0.018 14.4 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 EPE35614.1 - 0.0078 15.4 0.0 0.0096 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EPE35614.1 - 0.0087 15.6 0.3 0.32 10.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.14 EPE35614.1 - 0.013 14.9 0.0 0.037 13.4 0.0 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EPE35614.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.13 EPE35614.1 - 0.016 14.2 0.1 0.04 12.9 0.0 1.7 2 0 0 2 2 2 0 Septin MobB PF03205.9 EPE35614.1 - 0.025 14.2 0.1 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EPE35614.1 - 0.037 13.7 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 EPE35614.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 EPE35614.1 - 0.097 11.9 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B EamA PF00892.15 EPE35615.1 - 2.9e-09 37.0 31.8 3.9e-08 33.3 3.2 3.3 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EPE35615.1 - 1.6e-06 27.2 10.4 1.6e-06 27.2 7.2 2.0 2 1 0 2 2 2 1 UAA transporter family TPT PF03151.11 EPE35615.1 - 3.4e-06 26.7 0.6 3.4e-06 26.7 0.4 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family DUF914 PF06027.7 EPE35615.1 - 6.1e-06 25.3 8.2 6.1e-06 25.3 5.7 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EPE35615.1 - 1.8e-05 24.9 4.5 1.8e-05 24.9 3.1 2.8 3 0 0 3 3 3 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 EPE35615.1 - 0.78 9.5 9.2 0.25 11.1 0.9 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0546 Heme_oxygenase PF01126.15 EPE35616.1 - 1.5e-14 54.0 0.0 1.9e-12 47.2 0.0 2.8 2 1 0 2 2 2 2 Heme oxygenase Abhydrolase_6 PF12697.2 EPE35617.1 - 6.3e-22 78.5 0.0 8.5e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE35617.1 - 2.2e-09 37.2 0.2 3.3e-09 36.6 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EPE35617.1 - 0.0001 21.8 0.4 0.00017 21.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_1 PF00561.15 EPE35617.1 - 0.00029 20.4 0.0 0.00064 19.3 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EPE35617.1 - 0.0049 16.4 0.1 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 EPE35617.1 - 0.0062 15.9 0.1 0.0093 15.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 EPE35617.1 - 0.03 13.9 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 Serine hydrolase Hydrolase_4 PF12146.3 EPE35617.1 - 0.049 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Epimerase PF01370.16 EPE35618.1 - 4.6e-10 39.3 0.0 9.4e-09 35.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPE35618.1 - 8.2e-07 28.1 0.0 2.1e-05 23.5 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.8 EPE35618.1 - 4.6e-06 26.0 0.1 8.5e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EPE35618.1 - 7.4e-06 24.8 0.1 0.00059 18.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EPE35618.1 - 2.2e-05 24.7 0.1 4.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EPE35618.1 - 0.001 18.0 0.1 0.0018 17.2 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EPE35618.1 - 0.0085 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1034 PF06280.7 EPE35618.1 - 0.12 12.8 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Fn3-like domain (DUF1034) Fungal_trans PF04082.13 EPE35619.1 - 8.2e-11 41.2 0.0 3.2e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE35619.1 - 1.3e-08 34.5 13.9 2.3e-08 33.7 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transformer PF06495.6 EPE35619.1 - 0.059 13.2 5.3 0.85 9.4 3.1 2.2 2 0 0 2 2 2 0 Fruit fly transformer protein CorA PF01544.13 EPE35620.1 - 3.4e-12 45.9 0.0 5.8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Claudin_2 PF13903.1 EPE35620.1 - 0.0018 18.0 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction CorA PF01544.13 EPE35621.1 - 2.3e-13 49.8 1.8 8e-13 48.0 0.7 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF4335 PF14233.1 EPE35621.1 - 0.061 12.7 0.1 0.095 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) HET PF06985.6 EPE35624.1 - 9.2e-28 97.1 0.0 1.5e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clr2 PF10383.4 EPE35624.1 - 0.052 13.5 0.0 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 DUF815 PF05673.8 EPE35624.1 - 0.17 10.7 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HET PF06985.6 EPE35626.1 - 1.6e-05 25.1 1.3 0.018 15.2 0.9 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.18 EPE35628.1 - 2.8e-09 37.0 0.0 4.1e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EPE35628.1 - 3e-07 29.8 0.0 5.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EPE35628.1 - 7.4e-06 25.6 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EPE35628.1 - 0.0013 17.7 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase Sulfate_transp PF00916.15 EPE35629.1 - 2.6e-43 148.0 13.7 2.6e-43 148.0 9.5 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EPE35629.1 - 2.6e-21 75.0 2.6 2.6e-21 75.0 1.8 4.4 4 2 1 5 5 5 2 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EPE35629.1 - 2.3e-11 43.1 0.0 5.2e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain Strep_67kDa_ant PF06100.6 EPE35630.1 - 7.1e-156 519.4 0.0 8.3e-156 519.2 0.0 1.0 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 EPE35630.1 - 8e-06 25.7 0.3 2e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE35630.1 - 0.0021 17.0 0.0 0.012 14.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase PLRV_ORF5 PF01690.12 EPE35633.1 - 0.42 9.7 7.2 0.67 9.0 5.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DNase_NucA_NucB PF14040.1 EPE35636.1 - 3.4e-13 49.7 0.0 4.3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Endostatin PF06482.6 EPE35636.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin STE PF02200.11 EPE35639.1 - 1.8e-61 205.1 0.3 3.7e-61 204.0 0.2 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EPE35639.1 - 1.6e-11 43.8 11.9 2.4e-06 27.5 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE35639.1 - 1e-09 38.0 11.1 6e-05 23.1 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE35639.1 - 1.1e-09 38.0 8.0 3.5e-08 33.3 3.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EPE35639.1 - 0.00023 20.9 0.2 0.00023 20.9 0.2 2.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPE35639.1 - 0.00058 19.9 1.0 0.03 14.4 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 EPE35639.1 - 0.0098 15.8 0.2 0.022 14.7 0.2 1.6 1 0 0 1 1 1 1 zinc-finger zf-Di19 PF05605.7 EPE35639.1 - 0.4 10.8 3.2 0.83 9.8 2.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EPE35639.1 - 0.5 10.6 2.2 3.1 8.1 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type NmrA PF05368.8 EPE35640.1 - 4.7e-26 91.4 0.0 9.8e-26 90.4 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE35640.1 - 1.9e-09 37.7 0.0 2.8e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EPE35640.1 - 0.002 18.1 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EPE35640.1 - 0.04 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPE35640.1 - 0.16 10.6 0.0 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Gin PF10764.4 EPE35641.1 - 0.13 11.9 0.2 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin FlaC_arch PF05377.6 EPE35642.1 - 0.0011 18.8 0.5 0.0011 18.8 0.3 2.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 EPE35642.1 - 0.6 9.9 8.3 0.045 13.5 0.7 2.9 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA PF00004.24 EPE35643.1 - 5.7e-16 58.9 0.0 2.4e-15 56.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPE35643.1 - 8.6e-07 28.7 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPE35643.1 - 1.4e-05 25.1 0.0 4.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPE35643.1 - 0.00029 20.8 0.1 0.0018 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Zot PF05707.7 EPE35643.1 - 0.0056 16.1 0.1 0.051 13.0 0.1 2.2 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.1 EPE35643.1 - 0.046 13.4 0.2 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain CPT PF07931.7 EPE35643.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF89 PF01937.14 EPE35644.1 - 2.3e-129 431.2 0.0 3.1e-129 430.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 APH PF01636.18 EPE35645.1 - 1.8e-07 31.1 1.3 5.7e-07 29.5 0.9 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EPE35645.1 - 0.00083 18.5 0.0 0.0028 16.8 0.0 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 EPE35645.1 - 0.00093 17.9 0.0 0.0015 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EPE35645.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1514 PF07438.6 EPE35646.1 - 0.11 12.4 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) DUF3217 PF11506.3 EPE35647.1 - 0.022 14.4 0.0 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3217) Chalcone PF02431.10 EPE35647.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Chalcone-flavanone isomerase ABC_membrane PF00664.18 EPE35648.1 - 2.8e-74 249.9 41.1 3.1e-41 141.6 10.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPE35648.1 - 3.1e-65 218.6 0.0 2.5e-33 115.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPE35648.1 - 2.5e-15 56.3 4.1 9.5e-06 24.9 0.5 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE35648.1 - 2.3e-14 54.0 0.1 0.00036 20.5 0.1 4.5 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EPE35648.1 - 3.6e-09 36.8 0.6 0.00012 22.1 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.4 EPE35648.1 - 1.1e-08 34.1 0.5 0.0011 17.6 0.0 3.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_23 PF13476.1 EPE35648.1 - 4.8e-08 33.5 0.8 0.0018 18.6 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPE35648.1 - 5.5e-08 32.2 2.2 0.00065 19.1 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EPE35648.1 - 6.2e-08 32.8 0.4 0.047 13.8 0.1 3.9 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 EPE35648.1 - 2.7e-07 29.8 0.3 0.019 14.1 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EPE35648.1 - 3.1e-07 31.2 0.0 0.035 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPE35648.1 - 8.8e-06 25.3 0.0 0.22 11.2 0.0 3.6 3 0 0 3 3 3 2 Part of AAA domain SbcCD_C PF13558.1 EPE35648.1 - 2.2e-05 24.3 0.9 0.055 13.3 0.1 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EPE35648.1 - 3.8e-05 23.3 3.2 0.21 11.1 0.0 4.1 5 0 0 5 5 4 2 AAA domain AAA_25 PF13481.1 EPE35648.1 - 4.5e-05 22.9 1.5 0.22 10.9 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EPE35648.1 - 0.00018 21.0 1.5 0.17 11.2 0.0 3.4 4 1 0 4 4 4 2 AAA-like domain AAA_11 PF13086.1 EPE35648.1 - 0.00074 19.1 0.0 0.69 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 EPE35648.1 - 0.00075 19.0 0.6 0.41 10.1 0.0 2.9 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EPE35648.1 - 0.00088 19.5 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EPE35648.1 - 0.0012 18.5 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EPE35648.1 - 0.0014 18.8 3.5 1.2 9.3 0.0 4.8 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 EPE35648.1 - 0.0021 17.1 0.3 0.12 11.3 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EPE35648.1 - 0.0036 17.1 0.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPE35648.1 - 0.0061 16.2 0.1 7.7 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 EPE35648.1 - 0.012 15.1 0.1 2.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3987 PF13148.1 EPE35648.1 - 0.014 13.9 0.0 2.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Arch_ATPase PF01637.13 EPE35648.1 - 0.025 14.3 0.4 1.4 8.5 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase AAA_14 PF13173.1 EPE35648.1 - 0.026 14.4 0.1 17 5.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 EPE35648.1 - 0.028 14.2 0.3 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EPE35648.1 - 0.043 12.9 0.0 2.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.10 EPE35648.1 - 0.047 13.5 0.0 23 4.7 0.0 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit PRK PF00485.13 EPE35648.1 - 0.092 12.2 0.0 7.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 EPE35648.1 - 0.095 12.3 0.0 4.9 6.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 EPE35648.1 - 0.15 11.6 0.2 6.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EPE35648.1 - 0.15 12.2 0.2 37 4.5 0.0 3.2 3 0 0 3 3 3 0 RNA helicase NB-ARC PF00931.17 EPE35648.1 - 0.15 10.8 0.3 14 4.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain zf-LITAF-like PF10601.4 EPE35648.1 - 0.2 11.5 3.4 0.11 12.4 0.1 2.2 2 0 0 2 2 1 0 LITAF-like zinc ribbon domain IstB_IS21 PF01695.12 EPE35648.1 - 0.31 10.4 2.7 18 4.6 0.0 4.1 6 0 0 6 6 5 0 IstB-like ATP binding protein FSH1 PF03959.8 EPE35649.1 - 4.4e-31 107.9 0.0 1.6e-25 89.8 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) PE-PPE PF08237.6 EPE35649.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain ketoacyl-synt PF00109.21 EPE35650.1 - 1.7e-72 243.9 0.0 4.3e-72 242.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPE35650.1 - 8.7e-62 209.2 0.0 1.6e-61 208.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EPE35650.1 - 9.9e-61 204.5 0.5 2.3e-60 203.3 0.4 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EPE35650.1 - 5e-50 169.6 2.8 9.8e-50 168.7 0.6 2.4 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EPE35650.1 - 3.3e-48 164.3 0.0 5.3e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EPE35650.1 - 1.3e-41 141.1 0.1 6e-41 139.0 0.0 2.3 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.1 EPE35650.1 - 2.9e-11 44.3 0.0 1.3e-10 42.2 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EPE35650.1 - 1.1e-09 37.9 0.1 5.7e-09 35.6 0.1 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE35650.1 - 6.2e-09 35.5 0.2 2.2e-08 33.8 0.1 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EPE35650.1 - 0.00011 22.2 3.0 0.08 12.9 0.1 3.2 3 0 0 3 3 3 2 NADH(P)-binding PP-binding PF00550.20 EPE35650.1 - 0.00015 21.9 0.4 0.00038 20.6 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EPE35650.1 - 0.0002 20.4 0.0 0.00055 18.9 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain NmrA PF05368.8 EPE35650.1 - 0.0011 18.2 1.1 0.0032 16.7 0.1 2.3 3 0 0 3 3 3 1 NmrA-like family Semialdhyde_dh PF01118.19 EPE35650.1 - 0.077 13.3 0.2 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF2989 PF11207.3 EPE35650.1 - 0.086 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) Shikimate_DH PF01488.15 EPE35650.1 - 0.09 12.8 0.6 0.44 10.6 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_kinase PF01513.16 EPE35651.1 - 2.1e-47 161.2 0.0 3.3e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.16 EPE35652.1 - 2.3e-25 88.5 0.0 3.5e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.20 EPE35654.1 - 6.8e-24 84.4 0.0 1.5e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE35654.1 - 7.7e-09 34.9 0.0 1.1e-07 31.1 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE35654.1 - 0.025 13.5 0.0 0.05 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF87 PF01935.12 EPE35654.1 - 0.069 12.9 1.7 0.085 12.6 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 p450 PF00067.17 EPE35655.1 - 2.6e-43 148.2 0.0 9.9e-38 129.8 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 Peptidase_S41 PF03572.13 EPE35656.1 - 3.3e-07 29.8 0.0 5.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 APH PF01636.18 EPE35657.1 - 1.9e-14 54.0 0.0 3e-14 53.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE35657.1 - 1.7e-07 31.0 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPE35657.1 - 0.0054 15.9 0.0 0.012 14.7 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 EPE35657.1 - 0.13 10.9 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) SMN PF06003.7 EPE35659.1 - 0.067 12.2 6.0 0.11 11.5 4.2 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF605 PF04652.11 EPE35659.1 - 1.6 8.0 22.5 2.5 7.3 15.6 1.3 1 0 0 1 1 1 0 Vta1 like Acyl_transf_3 PF01757.17 EPE35660.1 - 1.2e-18 67.0 20.3 1.7e-18 66.5 14.1 1.1 1 0 0 1 1 1 1 Acyltransferase family Glyco_hydro_42C PF08533.5 EPE35662.1 - 0.037 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain DUF1579 PF07617.6 EPE35662.1 - 0.072 12.7 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1579) Nucleo_P87 PF07267.6 EPE35663.1 - 1.3 7.6 10.3 1.5 7.3 7.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CAF-1_p150 PF11600.3 EPE35666.1 - 0.17 11.2 4.2 0.27 10.5 2.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HET PF06985.6 EPE35667.1 - 8.7e-38 129.6 2.6 1.9e-37 128.5 1.8 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4003 PF13170.1 EPE35667.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Fibrillarin PF01269.12 EPE35669.1 - 1.5e-106 354.4 0.0 1.8e-106 354.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EPE35669.1 - 8.1e-06 25.5 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EPE35669.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EPE35669.1 - 0.069 12.7 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M20 PF01546.23 EPE35670.1 - 7.4e-25 87.5 0.0 2.7e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EPE35670.1 - 2e-16 60.2 0.0 4e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 Peptidase family M28 PA PF02225.17 EPE35670.1 - 1.8e-08 33.9 0.1 4.7e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 PA domain TFR_dimer PF04253.10 EPE35670.1 - 6.9e-07 28.8 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain M20_dimer PF07687.9 EPE35670.1 - 0.0023 17.6 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.11 EPE35671.1 - 2.6e-27 95.4 48.1 5.5e-27 94.4 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3624 PF12292.3 EPE35671.1 - 0.28 11.6 3.4 3.5 8.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3624) AMP-binding PF00501.23 EPE35672.1 - 0 1405.7 0.2 7.8e-90 301.2 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 EPE35672.1 - 0 1318.4 0.0 4.8e-52 176.6 0.0 11.4 10 1 0 10 10 10 9 Condensation domain PP-binding PF00550.20 EPE35672.1 - 5.7e-71 234.7 13.6 7.3e-12 45.3 0.1 8.0 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPE35672.1 - 1e-22 80.8 0.1 0.00025 21.9 0.0 6.0 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EPE35672.1 - 5.6e-10 38.2 0.0 0.22 9.9 0.0 5.3 5 0 0 5 5 5 4 Transferase family HxxPF_rpt PF13745.1 EPE35672.1 - 2.5e-07 30.8 0.2 0.094 13.0 0.0 5.6 6 0 0 6 6 6 2 HxxPF-repeated domain AATase PF07247.7 EPE35672.1 - 9.2e-05 21.1 4.2 5.5 5.4 0.0 6.4 5 1 0 5 5 5 2 Alcohol acetyltransferase Phage_min_cap2 PF06152.6 EPE35672.1 - 0.18 10.7 0.1 9.1 5.1 0.0 2.4 2 0 0 2 2 2 0 Phage minor capsid protein 2 ABC_tran PF00005.22 EPE35673.1 - 1.8e-44 151.3 0.0 2.2e-24 86.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPE35673.1 - 3.8e-34 118.3 29.7 6.2e-27 94.6 9.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EPE35673.1 - 1.1e-09 37.8 1.4 0.011 14.9 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE35673.1 - 9.7e-09 35.5 0.3 0.0073 16.3 0.0 3.6 2 1 1 3 3 3 2 AAA domain AAA_25 PF13481.1 EPE35673.1 - 9.2e-08 31.7 0.0 0.0033 16.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPE35673.1 - 3.8e-06 26.1 0.0 0.0015 17.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPE35673.1 - 8.4e-06 25.2 0.3 0.023 14.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EPE35673.1 - 1.7e-05 24.8 1.0 0.0082 16.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EPE35673.1 - 4.6e-05 23.3 0.0 0.057 13.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 EPE35673.1 - 8.2e-05 21.6 0.0 0.27 10.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 EPE35673.1 - 0.00011 22.4 0.6 0.054 13.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EPE35673.1 - 0.00013 22.4 0.2 0.27 11.7 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 EPE35673.1 - 0.00017 21.1 0.4 0.27 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA PF00004.24 EPE35673.1 - 0.00019 21.6 0.7 0.12 12.5 0.1 3.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EPE35673.1 - 0.00039 20.8 0.0 0.046 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EPE35673.1 - 0.002 17.9 0.5 0.19 11.5 0.0 2.4 2 0 0 2 2 2 1 Dynamin family DUF815 PF05673.8 EPE35673.1 - 0.003 16.5 0.1 2.3 7.1 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EPE35673.1 - 0.0035 17.0 0.0 0.069 12.8 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 EPE35673.1 - 0.0045 16.8 0.0 0.29 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPE35673.1 - 0.0057 17.4 1.1 2.4 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPE35673.1 - 0.0093 15.4 1.4 0.4 10.0 0.2 3.0 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EPE35673.1 - 0.01 16.0 0.0 2.3 8.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EPE35673.1 - 0.02 15.1 0.2 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EPE35673.1 - 0.033 13.8 0.6 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EPE35673.1 - 0.041 13.5 0.5 1.6 8.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Viral_helicase1 PF01443.13 EPE35673.1 - 0.041 13.3 0.1 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 EPE35673.1 - 0.048 13.3 0.1 3 7.5 0.1 3.1 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EPE35673.1 - 0.051 13.1 0.0 4.8 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EPE35673.1 - 0.055 13.3 0.0 0.79 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EPE35673.1 - 0.068 12.9 0.6 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 NB-ARC PF00931.17 EPE35673.1 - 0.07 11.9 0.1 2.7 6.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Guanylate_kin PF00625.16 EPE35673.1 - 0.085 12.2 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase Zeta_toxin PF06414.7 EPE35673.1 - 0.092 11.8 0.0 3.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF3671 PF12420.3 EPE35673.1 - 0.11 12.4 0.1 0.11 12.4 0.0 3.9 5 0 0 5 5 1 0 Protein of unknown function Adeno_IVa2 PF02456.10 EPE35673.1 - 0.13 10.8 0.1 3.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein PduV-EutP PF10662.4 EPE35673.1 - 1.3 8.4 3.4 1.8 8.0 0.0 2.6 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation TFIIA PF03153.8 EPE35674.1 - 0.25 11.2 3.7 0.32 10.8 2.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 EPE35674.1 - 6.5 4.9 12.9 7.8 4.6 8.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Tmemb_cc2 PF10267.4 EPE35674.1 - 8.1 4.9 6.7 11 4.5 4.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Gly_transf_sug PF04488.10 EPE35675.1 - 5.8e-10 39.4 0.0 9.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EPE35675.1 - 0.0081 15.3 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein HET PF06985.6 EPE35676.1 - 2.1e-38 131.6 1.4 5.6e-38 130.2 1.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FMN_red PF03358.10 EPE35677.1 - 2.7e-26 91.8 0.0 3.4e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EPE35677.1 - 9.6e-06 25.2 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Glyco_transf_90 PF05686.7 EPE35678.1 - 4.6e-14 51.9 1.6 1.1e-09 37.4 0.1 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 Arginase PF00491.16 EPE35679.1 - 1.6e-72 244.1 0.1 1.8e-72 243.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.18 EPE35680.1 - 8.4e-05 22.4 17.9 0.00016 21.4 12.4 1.5 1 1 0 1 1 1 1 Membrane-associating domain HET PF06985.6 EPE35681.1 - 1.1e-18 67.6 0.0 2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2306 PF10067.4 EPE35683.1 - 3.3e-13 49.6 10.1 3.3e-13 49.6 7.0 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) Herpes_UL45 PF05473.7 EPE35683.1 - 0.14 11.5 0.0 0.57 9.5 0.1 1.9 2 0 0 2 2 2 0 UL45 protein Microtub_assoc PF07989.6 EPE35684.1 - 5.9e-20 70.8 8.2 5.9e-20 70.8 5.7 9.4 9 2 1 10 10 10 1 Microtubule associated Mto2_bdg PF12808.2 EPE35684.1 - 4.7e-17 61.8 11.6 4.7e-17 61.8 8.1 12.1 11 2 1 12 12 12 3 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 EPE35684.1 - 0.00085 18.5 0.4 0.00085 18.5 0.3 6.0 4 2 0 5 5 5 3 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EPE35684.1 - 0.0075 16.1 17.2 0.0075 16.1 11.9 10.4 6 3 5 11 11 11 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 EPE35684.1 - 0.085 12.6 0.0 0.085 12.6 0.0 9.8 5 2 4 9 9 9 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 EPE35684.1 - 0.35 10.9 67.7 0.11 12.5 5.1 7.4 5 2 1 8 8 8 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 EPE35684.1 - 0.63 9.8 29.3 0.58 9.9 1.1 5.5 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus RrnaAD PF00398.15 EPE35685.1 - 9.4e-05 21.5 0.2 0.0003 19.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase JAB PF01398.16 EPE35686.1 - 8.6e-17 60.9 0.0 1.5e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EPE35686.1 - 1.1e-07 31.8 0.1 3.1e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.1 EPE35686.1 - 4.3e-07 29.4 0.2 1.6e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Lactamase_B PF00753.22 EPE35687.1 - 7.1e-17 61.6 3.0 9.6e-17 61.2 2.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPE35687.1 - 0.053 13.0 1.0 0.12 11.9 0.4 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain ADH_zinc_N PF00107.21 EPE35688.1 - 5.2e-21 74.5 0.0 9.3e-21 73.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPE35688.1 - 3e-19 68.7 0.1 5.9e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EPE35688.1 - 0.00076 19.0 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Alk_phosphatase PF00245.15 EPE35689.1 - 4.2e-65 220.0 0.2 6.3e-65 219.5 0.1 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EPE35689.1 - 6.1e-07 28.9 0.0 1.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EPE35689.1 - 1.4e-06 27.9 0.9 3.1e-06 26.7 0.7 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EPE35689.1 - 0.00042 18.8 0.2 0.00066 18.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) FTA4 PF13093.1 EPE35689.1 - 0.036 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1501 PF07394.7 EPE35689.1 - 0.05 12.4 0.1 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) adh_short PF00106.20 EPE35690.1 - 9e-15 54.9 0.0 2.6e-14 53.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE35690.1 - 1.1e-07 31.6 0.0 2.2e-07 30.7 0.0 1.4 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EPE35690.1 - 0.00044 20.0 0.0 0.00084 19.1 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Lipase_GDSL_2 PF13472.1 EPE35691.1 - 9e-12 45.4 0.0 1.7e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Red1 PF07964.6 EPE35691.1 - 0.06 11.5 0.0 0.091 10.9 0.0 1.2 1 0 0 1 1 1 0 Rec10 / Red1 FixP_N PF14715.1 EPE35693.1 - 1.2 8.5 9.0 2.3 7.6 6.2 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP TMEM154 PF15102.1 EPE35694.1 - 0.0016 18.1 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.11 EPE35694.1 - 0.0061 14.8 0.1 0.02 13.1 0.1 1.9 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Rifin_STEVOR PF02009.11 EPE35694.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 EPE35694.1 - 0.048 14.0 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EPE35694.1 - 0.27 10.8 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SIT PF15330.1 EPE35694.1 - 0.28 11.3 0.1 0.28 11.3 0.0 3.1 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT SKG6 PF08693.5 EPE35694.1 - 0.49 9.7 3.0 0.88 8.9 2.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HET PF06985.6 EPE35695.1 - 2.9e-22 79.3 8.9 2e-19 70.1 0.6 2.6 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EPE35697.1 - 5.7e-37 127.2 32.7 6.5e-35 120.4 17.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE35697.1 - 3.6e-07 29.1 15.3 3.6e-07 29.1 10.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EPE35697.1 - 0.69 9.7 7.9 0.29 10.9 2.7 2.7 2 1 0 2 2 2 0 MFS_1 like family Fructosamin_kin PF03881.9 EPE35698.1 - 1.5e-35 122.6 0.0 1.9e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EPE35698.1 - 0.056 13.1 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NACHT PF05729.7 EPE35699.1 - 0.00015 21.4 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 EPE35699.1 - 0.00045 19.8 0.2 0.0016 18.0 0.1 1.9 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EPE35699.1 - 0.00045 20.1 0.0 0.0078 16.1 0.0 3.0 3 1 0 3 3 3 1 Alpha/beta hydrolase family DUF676 PF05057.9 EPE35699.1 - 0.0012 18.1 0.0 0.0037 16.5 0.0 1.8 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.1 EPE35699.1 - 0.0032 17.4 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF4117 PF13491.1 EPE35700.1 - 3.8 6.9 9.0 0.33 10.3 3.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) HET PF06985.6 EPE35701.1 - 1.8e-21 76.7 0.4 3.8e-21 75.7 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.18 EPE35702.1 - 3.9e-16 59.5 0.0 7.8e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE35702.1 - 0.0025 17.3 0.1 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase GatB_N PF02934.10 EPE35705.1 - 1.6e-104 348.8 0.0 2.2e-104 348.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EPE35705.1 - 1.6e-18 66.8 0.0 3.5e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 GatB domain zf-H2C2 PF09337.5 EPE35706.1 - 4.4e-21 74.0 5.4 6.9e-21 73.3 3.8 1.3 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 EPE35706.1 - 5.8e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EPE35706.1 - 0.00095 19.1 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPE35706.1 - 0.0044 17.1 0.0 0.0098 16.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE35706.1 - 0.037 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Aldose_epim PF01263.15 EPE35707.1 - 1.1e-61 208.5 0.1 1.4e-61 208.1 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Acyl-CoA_dh_1 PF00441.19 EPE35708.1 - 4.7e-41 140.3 0.1 7.6e-41 139.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPE35708.1 - 4.6e-20 70.8 0.1 9.1e-20 69.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EPE35708.1 - 2.5e-18 66.6 0.0 5.3e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 EPE35708.1 - 2.5e-17 62.4 0.2 4.7e-17 61.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 EPE35708.1 - 1.3e-07 31.9 0.0 3.5e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cys_rich_VLP PF14194.1 EPE35708.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP Cpn60_TCP1 PF00118.19 EPE35709.1 - 3e-142 474.6 2.7 3.6e-142 474.4 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSDR_N_2 PF13588.1 EPE35709.1 - 0.075 12.8 0.5 0.68 9.7 0.1 2.5 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF1996 PF09362.5 EPE35710.1 - 1.9e-85 286.2 8.4 6.3e-85 284.5 3.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) Peptidase_M28 PF04389.12 EPE35711.1 - 5.1e-32 111.0 0.0 7.7e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EPE35711.1 - 1.5e-05 24.5 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Fringe PF02434.11 EPE35713.1 - 1.1e-06 28.0 1.8 0.00048 19.4 1.2 3.1 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 EPE35713.1 - 0.0016 18.1 0.4 0.0039 16.8 0.3 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 EPE35713.1 - 0.026 14.1 0.1 0.05 13.2 0.1 1.4 1 0 0 1 1 1 0 PAN-like domain Fungal_trans PF04082.13 EPE35717.1 - 3e-17 62.3 0.8 4.1e-17 61.9 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE35717.1 - 6.6e-08 32.3 9.3 6.6e-08 32.3 6.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE35718.1 - 1.3e-33 116.2 38.5 1.7e-33 115.7 26.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF155 PF02582.9 EPE35719.1 - 1.5e-42 145.4 0.0 2.4e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Sigma70_r4 PF04545.11 EPE35719.1 - 0.082 12.2 0.1 0.23 10.7 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Cupin_1 PF00190.17 EPE35719.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 Cupin P12 PF12669.2 EPE35719.1 - 0.2 11.8 0.2 0.35 11.1 0.1 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family Clathrin PF00637.15 EPE35720.1 - 2e-20 72.8 0.2 4.1e-19 68.5 0.5 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 EPE35720.1 - 0.0002 21.1 0.7 0.28 11.1 0.1 4.2 3 1 0 3 3 3 1 WD domain, G-beta repeat zf-RING_2 PF13639.1 EPE35720.1 - 0.0033 17.2 1.2 0.01 15.6 0.8 1.8 1 1 0 1 1 1 1 Ring finger domain Vps39_1 PF10366.4 EPE35720.1 - 0.18 11.8 0.6 0.99 9.4 0.1 2.4 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.1 EPE35720.1 - 0.24 11.1 2.2 0.62 9.8 1.6 1.7 1 1 0 1 1 1 0 zinc-RING finger domain TPR_MLP1_2 PF07926.7 EPE35721.1 - 0.0016 18.2 41.7 0.0036 17.0 0.1 4.1 4 1 0 4 4 4 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EPE35721.1 - 0.036 13.2 27.3 0.02 14.0 4.4 3.9 2 2 3 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EPE35721.1 - 0.043 12.2 44.3 0.027 12.9 19.4 3.3 1 1 1 2 2 2 0 AAA domain TMF_DNA_bd PF12329.3 EPE35721.1 - 0.21 11.4 61.3 0.055 13.2 7.3 5.9 4 2 1 5 5 5 0 TATA element modulatory factor 1 DNA binding LPP PF04728.8 EPE35721.1 - 0.39 10.5 13.0 25 4.7 0.1 4.9 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Surfac_D-trimer PF09006.6 EPE35721.1 - 0.57 9.9 7.7 5.5 6.7 0.0 5.0 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation CENP-Q PF13094.1 EPE35721.1 - 0.64 10.0 59.7 0.66 9.9 0.1 5.5 3 2 1 5 5 5 0 CENP-Q, a CENPA-CAD centromere complex subunit Med9 PF07544.8 EPE35721.1 - 1.1 8.9 28.8 0.61 9.8 0.6 6.3 4 2 2 6 6 6 0 RNA polymerase II transcription mediator complex subunit 9 AlkA_N PF06029.6 EPE35721.1 - 1.5 8.9 4.9 0.72 9.9 0.6 2.5 2 0 0 2 2 2 0 AlkA N-terminal domain IncA PF04156.9 EPE35721.1 - 2.5 7.6 66.7 0.018 14.6 15.6 5.2 3 2 1 4 4 4 0 IncA protein Filament PF00038.16 EPE35721.1 - 3.9 6.8 56.3 3.7 6.9 5.2 3.7 3 1 0 3 3 3 0 Intermediate filament protein WEMBL PF05701.6 EPE35721.1 - 7.7 4.8 56.6 0.12 10.7 24.4 3.2 2 1 0 3 3 3 0 Weak chloroplast movement under blue light bZIP_1 PF00170.16 EPE35721.1 - 7.9 6.5 32.6 0.062 13.2 1.4 6.6 6 0 0 6 6 6 0 bZIP transcription factor Methyltransf_2 PF00891.13 EPE35722.1 - 5e-22 78.2 0.1 6.8e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EPE35722.1 - 0.0044 16.8 0.0 0.017 14.9 0.0 2.1 1 0 0 1 1 1 1 Dimerisation domain DUF4220 PF13968.1 EPE35723.1 - 0.16 11.0 2.3 0.22 10.5 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF4241 PF14025.1 EPE35723.1 - 0.49 10.1 3.2 0.7 9.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) DUF1744 PF08490.7 EPE35724.1 - 6e-152 505.8 0.0 8.4e-152 505.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EPE35724.1 - 2.3e-61 207.4 0.1 5e-61 206.3 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EPE35724.1 - 4.2e-23 81.8 0.3 2.2e-22 79.4 0.4 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EPE35724.1 - 1.4e-07 31.2 0.1 4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DUF3767 PF12597.3 EPE35725.1 - 4.2e-36 123.1 0.5 1.1e-35 121.8 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) Prefoldin PF02996.12 EPE35725.1 - 0.52 9.9 4.5 0.85 9.2 3.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit NmrA PF05368.8 EPE35726.1 - 5.3e-30 104.4 0.0 1.9e-29 102.5 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE35726.1 - 0.00012 22.1 0.2 0.00016 21.7 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EPE35726.1 - 0.0084 16.1 0.2 0.013 15.4 0.2 1.3 1 0 0 1 1 1 1 TrkA-N domain DUF3632 PF12311.3 EPE35727.1 - 1.7e-22 80.1 0.2 3.2e-22 79.2 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) Gly_transf_sug PF04488.10 EPE35730.1 - 8.5e-10 38.9 0.0 1.7e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif ODV-E18 PF10717.4 EPE35730.1 - 0.13 11.6 0.6 0.27 10.6 0.4 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Nucleo_P87 PF07267.6 EPE35734.1 - 0.33 9.5 1.7 0.35 9.4 1.2 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RICH PF05062.7 EPE35735.1 - 0.39 10.8 2.4 0.45 10.6 0.2 1.9 2 0 0 2 2 2 0 RICH domain DUF4106 PF13388.1 EPE35736.1 - 2.5 6.9 12.0 3 6.6 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Synaptobrevin PF00957.16 EPE35737.1 - 8.1e-32 108.6 0.4 1.2e-31 108.1 0.0 1.5 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 EPE35737.1 - 7.3e-24 83.1 0.0 1.1e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SUV3_C PF12513.3 EPE35738.1 - 2.4e-15 55.6 0.4 4.8e-15 54.7 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EPE35738.1 - 1.1e-08 34.7 0.0 5e-08 32.6 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TK PF00265.13 EPE35738.1 - 0.08 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase HET PF06985.6 EPE35739.1 - 4.9e-23 81.8 0.5 1.5e-22 80.2 0.0 2.1 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) FNIP_N PF14636.1 EPE35740.1 - 3e-27 95.6 0.3 3e-27 95.6 0.2 3.6 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 EPE35740.1 - 0.072 12.6 0.1 0.58 9.6 0.0 2.1 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain Acetyltransf_7 PF13508.1 EPE35741.1 - 1.3e-07 31.6 0.0 3.4e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE35741.1 - 0.00013 21.8 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EPE35741.1 - 0.00053 19.8 0.0 0.002 17.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE35741.1 - 0.062 13.4 0.0 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE35741.1 - 0.095 12.4 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein DUF3608 PF12257.3 EPE35742.1 - 4.1e-74 249.0 0.0 6.7e-74 248.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EPE35742.1 - 4.6e-31 106.3 0.1 9e-31 105.4 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Sec1 PF00995.18 EPE35745.1 - 2.8e-138 462.0 0.0 3.3e-138 461.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.18 EPE35746.1 - 3.9e-08 32.9 0.2 8.8e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 G-patch domain DUF1682 PF07946.9 EPE35746.1 - 2.8 6.7 5.9 4 6.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) adh_short PF00106.20 EPE35747.1 - 5.5e-14 52.4 0.8 1.4e-13 51.0 0.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EPE35747.1 - 7.5e-07 28.9 0.0 1.9e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPE35747.1 - 0.00043 20.0 0.1 0.00086 19.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EPE35747.1 - 0.0062 16.5 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EPE35747.1 - 0.04 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Zn_clus PF00172.13 EPE35748.1 - 1.3e-06 28.1 9.8 3.3e-06 26.8 6.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 EPE35749.1 - 2.4e-13 50.1 0.1 7.8e-13 48.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPE35749.1 - 1.9e-08 34.5 0.9 1.1e-07 32.0 0.6 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE35749.1 - 1.3e-07 30.5 0.0 7.8e-07 28.0 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EPE35749.1 - 0.0026 17.0 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EPE35749.1 - 0.098 11.5 0.2 1.3 7.9 0.2 2.1 1 1 0 1 1 1 0 Male sterility protein adh_short PF00106.20 EPE35749.1 - 0.1 12.4 0.1 0.3 10.9 0.1 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Stig1 PF04885.8 EPE35750.1 - 0.00085 19.5 26.1 0.00085 19.5 18.1 3.1 2 1 2 4 4 4 1 Stigma-specific protein, Stig1 CAP_N PF01213.14 EPE35750.1 - 0.19 10.9 1.3 0.29 10.3 0.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EPE35750.1 - 7.7 5.7 6.3 5.9 6.1 3.2 1.5 1 1 0 2 2 2 0 Mitochondrial fission regulator HEAT_2 PF13646.1 EPE35751.1 - 1.2e-32 112.0 5.5 8.9e-16 57.9 0.0 3.9 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 EPE35751.1 - 2.6e-19 67.6 2.5 0.022 15.2 0.0 7.1 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EPE35751.1 - 1.5e-09 38.0 8.7 0.00076 19.9 0.2 4.6 4 1 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EPE35751.1 - 3.1e-08 33.0 4.4 0.38 10.9 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.18 EPE35751.1 - 0.0079 15.9 0.2 3.4 7.6 0.0 3.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Nipped-B_C PF12830.2 EPE35752.1 - 1.5e-51 174.7 0.3 2.5e-48 164.2 0.0 2.7 2 0 0 2 2 2 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EPE35752.1 - 6.9e-07 29.1 1.6 1.5e-06 27.9 0.2 2.5 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 EPE35752.1 - 0.0017 18.6 5.4 0.02 15.1 0.4 4.7 6 0 0 6 6 6 1 HEAT repeats HEAT PF02985.17 EPE35752.1 - 0.096 12.8 6.8 15 5.9 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat UPF0147 PF03685.8 EPE35752.1 - 0.11 12.3 2.4 0.56 10.1 0.3 3.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) DUF4066 PF13278.1 EPE35753.1 - 3.5e-24 84.9 0.0 5e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EPE35753.1 - 1.7e-09 37.2 0.0 2.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Abhydrolase_3 PF07859.8 EPE35754.1 - 6.8e-56 189.1 0.0 1e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EPE35754.1 - 1.3e-08 34.0 0.0 3.5e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EPE35754.1 - 6.5e-06 25.9 0.0 9.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE35754.1 - 1.7e-05 24.1 0.1 0.00014 21.1 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EPE35754.1 - 0.0016 17.3 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2424 PF10340.4 EPE35754.1 - 0.0018 17.0 0.0 0.002 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Esterase_phd PF10503.4 EPE35754.1 - 0.0049 16.1 0.0 0.009 15.2 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Lipase_3 PF01764.20 EPE35754.1 - 0.0065 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EPE35754.1 - 0.0071 16.2 0.2 0.014 15.2 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE35754.1 - 0.0071 15.8 0.0 0.03 13.7 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 EPE35754.1 - 0.018 13.5 0.0 0.066 11.7 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 EPE35754.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HET PF06985.6 EPE35755.1 - 2e-09 37.7 0.0 3.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2HC5 PF06221.8 EPE35756.1 - 1.7e-21 75.7 5.0 2.6e-21 75.0 3.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Syja_N PF02383.13 EPE35757.1 - 6.3e-91 304.4 0.0 1.2e-90 303.5 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain DnaJ PF00226.26 EPE35758.1 - 6.8e-15 54.5 0.0 1.2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2454 PF10521.4 EPE35759.1 - 1e-56 192.0 6.8 5e-55 186.4 4.7 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EPE35760.1 - 4.8e-26 91.4 0.1 1.1e-25 90.2 0.0 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EPE35760.1 - 4.7e-09 35.6 0.0 1.1e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A UPF0052 PF01933.13 EPE35760.1 - 0.079 12.2 0.0 0.25 10.6 0.0 1.7 1 1 1 2 2 2 0 Uncharacterised protein family UPF0052 TRAPPC-Trs85 PF12739.2 EPE35761.1 - 6.2e-115 384.1 0.5 9e-115 383.6 0.4 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit HRXXH PF13933.1 EPE35762.1 - 1.2e-07 31.3 4.2 2e-07 30.7 2.9 1.2 1 0 0 1 1 1 1 Putative peptidase family TauD PF02668.11 EPE35764.1 - 3.8e-55 187.3 0.4 4.6e-55 187.0 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family P16-Arc PF04699.9 EPE35764.1 - 0.13 12.2 0.1 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) NMD3 PF04981.8 EPE35765.1 - 2.4e-73 246.1 3.5 4e-73 245.4 2.5 1.4 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.3 EPE35765.1 - 0.0014 18.5 0.2 0.33 10.9 0.0 2.7 2 0 0 2 2 2 2 Rubredoxin-like zinc ribbon domain (DUF35_N) HypA PF01155.14 EPE35765.1 - 0.75 9.5 5.1 20 4.8 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EPE35765.1 - 1.2 9.0 10.5 7 6.5 3.4 2.8 2 1 0 2 2 2 0 Double zinc ribbon Ank_2 PF12796.2 EPE35767.1 - 2e-10 40.8 0.1 2e-07 31.2 0.1 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE35767.1 - 4.9e-10 39.6 2.1 0.00021 21.6 0.1 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EPE35767.1 - 8e-09 34.8 0.3 2.4e-05 23.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EPE35767.1 - 4.7e-08 33.0 0.4 0.0036 17.4 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE35767.1 - 1.5e-07 30.9 0.8 0.0081 16.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EPE35767.1 - 7e-05 22.4 0.2 0.00087 18.8 0.2 2.5 1 1 0 1 1 1 1 KilA-N domain AAA_13 PF13166.1 EPE35767.1 - 0.11 10.9 7.1 0.18 10.2 4.9 1.2 1 0 0 1 1 1 0 AAA domain Filament PF00038.16 EPE35767.1 - 0.23 10.8 17.6 0.59 9.5 0.2 2.3 2 0 0 2 2 2 0 Intermediate filament protein Phage_GPO PF05929.6 EPE35767.1 - 0.29 10.3 4.7 0.58 9.3 3.3 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase HAUS6_N PF14661.1 EPE35767.1 - 0.41 9.9 10.3 8.1 5.7 5.2 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Mnd1 PF03962.10 EPE35767.1 - 8.2 6.0 13.7 4.1 7.0 7.2 2.0 2 0 0 2 2 2 0 Mnd1 family OmpH PF03938.9 EPE35767.1 - 9.3 6.1 22.2 4.2e+02 0.7 15.4 2.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Complex1_LYR PF05347.10 EPE35768.1 - 1.2e-09 37.8 5.2 6e-09 35.5 2.4 2.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPE35768.1 - 1.9e-08 34.3 2.6 1.9e-08 34.3 1.8 1.8 2 0 0 2 2 2 1 Complex1_LYR-like Acetyltransf_1 PF00583.19 EPE35769.1 - 5.8e-16 58.3 0.0 9.8e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPE35769.1 - 1.5e-07 31.0 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EPE35769.1 - 2e-06 27.8 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPE35769.1 - 0.00013 22.0 0.0 0.00037 20.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPE35769.1 - 0.0015 18.6 0.0 0.0037 17.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE35769.1 - 0.033 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EPE35769.1 - 0.036 13.9 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_11 PF13414.1 EPE35770.1 - 4.7e-11 42.1 6.6 6.8e-06 25.6 0.0 5.2 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.12 EPE35770.1 - 2.9e-06 26.7 9.7 0.021 14.7 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE35770.1 - 1.9e-05 25.2 7.6 2.4e-05 24.8 0.7 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EPE35770.1 - 0.0023 17.9 0.1 14 6.1 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPE35770.1 - 0.0078 15.9 2.8 2 8.3 0.1 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPE35770.1 - 0.036 13.9 15.1 0.14 12.1 0.6 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPE35770.1 - 0.053 14.1 11.8 0.24 12.1 1.0 5.2 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPE35770.1 - 0.057 13.2 6.0 0.074 12.8 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPE35770.1 - 0.12 12.0 7.7 9.4 6.0 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Epimerase PF01370.16 EPE35772.1 - 7.8e-24 84.4 0.0 1.1e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPE35772.1 - 2.3e-07 30.0 0.0 3.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EPE35772.1 - 9.5e-07 27.9 0.0 1.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EPE35772.1 - 1.7e-05 23.6 0.0 5.9e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPE35772.1 - 1.8e-05 24.7 0.0 6.5e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPE35772.1 - 0.00019 20.4 0.0 0.0041 16.0 0.1 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EPE35772.1 - 0.0093 15.2 0.2 2.6 7.2 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family AP_endonuc_2 PF01261.19 EPE35772.1 - 0.051 12.8 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Cys_Met_Meta_PP PF01053.15 EPE35773.1 - 2.9e-08 32.4 0.0 4.2e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme APH PF01636.18 EPE35774.1 - 0.0036 17.0 0.1 0.017 14.8 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EPE35774.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase GYF PF02213.11 EPE35775.1 - 3e-17 61.9 0.1 2.4e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 GYF domain Abhydrolase_3 PF07859.8 EPE35776.1 - 1.4e-46 158.7 0.2 1.8e-46 158.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EPE35776.1 - 1.9e-13 50.0 0.0 2.8e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EPE35776.1 - 0.00015 21.5 0.1 0.00022 21.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE35776.1 - 0.00076 18.7 0.0 0.0093 15.2 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.13 EPE35776.1 - 0.04 13.1 0.1 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Fungal_trans PF04082.13 EPE35777.1 - 1.6e-27 95.9 6.8 3.1e-27 95.1 4.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE35777.1 - 3.6e-09 36.3 11.0 7.9e-09 35.2 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE35778.1 - 2.7e-35 121.7 39.8 2.7e-35 121.7 27.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE35778.1 - 1.7e-09 36.4 6.9 3e-09 35.6 4.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE35778.1 - 8.2e-09 34.5 17.1 8.2e-09 34.5 11.8 2.5 1 1 1 3 3 3 1 Sugar (and other) transporter Rb_C PF08934.5 EPE35779.1 - 0.076 12.6 0.3 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 Rb C-terminal domain Abhydrolase_6 PF12697.2 EPE35781.1 - 8.2e-30 104.3 0.1 3.2e-29 102.4 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE35781.1 - 2.3e-14 53.5 0.3 1.8e-13 50.5 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE35781.1 - 5e-13 49.0 0.0 7.4e-10 38.7 0.0 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE35781.1 - 9.2e-10 38.2 0.0 2.1e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 EPE35781.1 - 1.7e-05 24.3 0.9 7.7e-05 22.2 0.6 1.9 1 1 0 1 1 1 1 Putative esterase Cofilin_ADF PF00241.15 EPE35782.1 - 2.8e-09 36.9 0.0 3.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF4363 PF14276.1 EPE35783.1 - 0.051 13.2 0.3 6.2 6.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Laminin_I PF06008.9 EPE35783.1 - 0.053 12.8 0.1 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Laminin Domain I Aldedh PF00171.17 EPE35785.1 - 5e-135 450.4 0.0 5.6e-135 450.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPE35785.1 - 2.8e-06 26.3 0.0 6.6e-06 25.0 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF2229 PF09989.4 EPE35785.1 - 0.073 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF3071 PF11268.3 EPE35785.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) RRM_6 PF14259.1 EPE35786.1 - 4.2e-09 36.2 0.0 1.6e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE35786.1 - 1.2e-07 31.2 0.1 3.3e-05 23.4 0.1 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE35786.1 - 3.6e-05 23.5 0.0 0.00066 19.4 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAR2 PF05282.6 EPE35786.1 - 0.74 8.6 5.5 0.19 10.6 0.4 1.9 2 0 0 2 2 2 0 AAR2 protein Gly-zipper_Omp PF13488.1 EPE35787.1 - 0.0025 17.4 11.2 0.0025 17.4 7.8 2.4 2 0 0 2 2 2 1 Glycine zipper Rick_17kDa_Anti PF05433.10 EPE35787.1 - 0.0083 15.7 19.6 0.0083 15.7 13.6 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain SR-25 PF10500.4 EPE35787.1 - 0.16 11.4 7.7 0.24 10.8 5.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATPase_gene1 PF09527.5 EPE35787.1 - 0.9 9.3 8.6 1.4 8.7 6.0 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) PAT1 PF09770.4 EPE35788.1 - 0.41 8.8 24.3 0.49 8.5 16.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 EPE35789.1 - 7.8e-24 84.2 0.0 3.9e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE35789.1 - 4.8e-11 42.2 0.0 3.5e-07 29.5 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase USP8_interact PF08941.5 EPE35789.1 - 0.21 10.9 0.8 0.41 9.9 0.1 1.8 2 0 0 2 2 2 0 USP8 interacting PEHE PF15275.1 EPE35790.1 - 0.015 15.7 0.2 0.056 13.8 0.1 1.9 1 0 0 1 1 1 0 PEHE domain HrpB1_HrpK PF09613.5 EPE35791.1 - 0.11 11.9 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF1237 PF06824.6 EPE35792.1 - 1.1e-180 600.8 0.0 1.2e-180 600.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Aminotran_5 PF00266.14 EPE35793.1 - 4.8e-20 71.6 0.0 1.1e-19 70.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.11 EPE35794.1 - 3.8e-37 127.8 28.3 5.2e-37 127.3 19.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C3H1 PF10650.4 EPE35795.1 - 2.3e-12 46.1 4.1 3.6e-12 45.5 2.8 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Resolvase PF00239.16 EPE35795.1 - 0.0046 16.8 1.1 0.018 14.9 0.8 2.0 1 0 0 1 1 1 1 Resolvase, N terminal domain IncA PF04156.9 EPE35795.1 - 7.8 6.0 25.7 41 3.7 17.8 2.2 1 1 1 2 2 2 0 IncA protein Myosin_head PF00063.16 EPE35796.1 - 3.4e-248 825.2 0.0 3.4e-248 825.2 0.0 2.8 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EPE35796.1 - 1.4e-31 109.0 271.1 7.9e-23 80.1 77.9 5.9 3 2 1 4 4 4 4 Myosin tail Myosin_N PF02736.14 EPE35796.1 - 7.3e-07 28.7 0.2 1.8e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 EPE35796.1 - 0.069 12.9 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EPE35796.1 - 0.22 11.6 0.0 0.22 11.6 0.0 5.2 4 2 0 4 4 4 0 AAA domain Filament PF00038.16 EPE35796.1 - 0.89 8.9 0.0 0.0093 15.4 7.3 9.1 2 2 4 7 7 7 0 Intermediate filament protein But2 PF09792.4 EPE35797.1 - 4.4e-51 172.4 4.3 4.4e-51 172.4 3.0 3.1 3 1 1 4 4 4 1 Ubiquitin 3 binding protein But2 C-terminal domain Arginase PF00491.16 EPE35799.1 - 0.0058 15.9 0.0 0.0071 15.6 0.0 1.1 1 0 0 1 1 1 1 Arginase family Arginase PF00491.16 EPE35800.1 - 3.3e-64 216.8 0.1 3.3e-62 210.2 0.0 2.0 1 1 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EPE35800.1 - 0.051 13.7 0.2 0.08 13.1 0.2 1.3 1 0 0 1 1 1 0 UPF0489 domain tRNA-synt_2 PF00152.15 EPE35801.1 - 5e-06 25.5 0.0 5.8e-06 25.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) ABC_tran PF00005.22 EPE35803.1 - 1.9e-06 28.1 0.5 0.0012 19.1 0.1 2.6 1 1 1 2 2 2 2 ABC transporter AAA_23 PF13476.1 EPE35803.1 - 2.4e-06 28.0 0.1 4.4e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EPE35803.1 - 2.6e-06 26.8 0.0 0.0059 15.8 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE35803.1 - 1.2e-05 25.4 0.1 3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EPE35803.1 - 6.3e-05 22.4 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EPE35803.1 - 6.7e-05 22.1 0.3 0.00011 21.4 0.0 1.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EPE35803.1 - 0.00071 19.4 0.0 0.0067 16.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE35803.1 - 0.00077 19.6 0.5 0.0097 16.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EPE35803.1 - 0.0013 18.4 0.2 0.0033 17.0 0.1 1.9 1 1 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.12 EPE35803.1 - 0.0053 16.2 0.1 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EPE35803.1 - 0.006 16.5 0.1 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EPE35803.1 - 0.0074 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPE35803.1 - 0.013 14.7 0.0 0.029 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF2813 PF11398.3 EPE35803.1 - 0.02 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_5 PF07728.9 EPE35803.1 - 0.028 14.1 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EPE35803.1 - 0.036 14.3 0.0 0.083 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EPE35803.1 - 0.042 13.5 0.2 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA PF00004.24 EPE35803.1 - 0.043 14.0 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HET PF06985.6 EPE35805.1 - 1.8e-27 96.2 1.1 2.7e-25 89.1 0.7 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Response_reg PF00072.19 EPE35806.1 - 5.6e-21 74.6 0.0 1.9e-14 53.5 0.0 2.4 1 1 1 2 2 2 2 Response regulator receiver domain PRCC PF10253.4 EPE35806.1 - 0.038 14.6 2.0 11 6.7 0.2 3.3 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Pkinase PF00069.20 EPE35807.1 - 2.1e-51 174.5 0.0 3.4e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE35807.1 - 1.1e-23 83.6 0.1 3.3e-23 82.0 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE35807.1 - 0.0095 14.9 0.3 0.27 10.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like YodA PF09223.6 EPE35807.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 YodA lipocalin-like domain SGL PF08450.7 EPE35808.1 - 4.5e-05 22.9 0.1 0.00048 19.5 0.1 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Acetyltransf_1 PF00583.19 EPE35809.1 - 5.5e-09 35.9 0.1 1.1e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE35809.1 - 1.6e-05 24.9 0.0 5.2e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPE35809.1 - 0.00012 22.2 0.1 0.00056 20.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE35809.1 - 0.00035 20.4 0.0 0.00058 19.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EPE35809.1 - 0.03 14.4 0.2 0.086 12.9 0.1 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Fasciclin PF02469.17 EPE35810.1 - 2e-29 102.2 0.6 1.5e-15 57.3 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain SKG6 PF08693.5 EPE35810.1 - 0.00082 18.6 0.3 0.0019 17.4 0.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SIT PF15330.1 EPE35810.1 - 0.013 15.6 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Herpes_gE PF02480.11 EPE35810.1 - 0.026 12.7 0.1 0.038 12.2 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Herpes_UL43 PF05072.8 EPE35810.1 - 0.028 13.1 0.1 5.3 5.6 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL43 protein Mid2 PF04478.7 EPE35810.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF1180 PF06679.7 EPE35810.1 - 0.054 13.3 1.0 0.12 12.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TMEM154 PF15102.1 EPE35810.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family CorA PF01544.13 EPE35811.1 - 2.6e-14 52.9 8.8 3.6e-14 52.4 4.9 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Asp PF00026.18 EPE35814.1 - 1.7e-13 50.5 0.0 2.9e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Shisa PF13908.1 EPE35814.1 - 0.058 13.5 4.6 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 EPE35814.1 - 0.15 10.2 0.1 0.25 9.5 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF822 PF05687.8 EPE35814.1 - 0.66 10.3 3.6 2.2 8.6 2.5 1.9 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Potass_KdpF PF09604.5 EPE35814.1 - 3 7.7 7.5 7 6.6 5.2 1.6 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) FAA_hydrolase_N PF09298.6 EPE35816.1 - 0.03 14.3 0.5 0.065 13.2 0.4 1.6 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal APH PF01636.18 EPE35818.1 - 1.5e-12 47.7 0.0 2.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_1 PF00515.23 EPE35820.1 - 3.8e-24 83.2 6.2 0.00011 21.6 0.3 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 EPE35820.1 - 2e-23 80.3 8.6 0.00091 18.9 0.6 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 EPE35820.1 - 6.8e-21 73.6 11.6 3.1e-08 33.1 0.8 7.0 5 3 1 7 7 7 5 TPR repeat Apc3 PF12895.2 EPE35820.1 - 4.8e-16 58.6 13.7 8.1e-15 54.7 0.4 4.3 4 2 1 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EPE35820.1 - 1.9e-15 57.0 14.4 5.7e-08 33.2 0.8 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPE35820.1 - 3.6e-12 45.1 1.5 0.043 13.5 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPE35820.1 - 5.4e-11 42.2 11.7 0.0034 17.2 0.4 7.7 4 3 5 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPE35820.1 - 1.1e-09 38.4 5.9 0.0035 17.6 0.5 5.5 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPE35820.1 - 2.4e-09 37.0 7.4 0.0071 16.8 0.2 7.9 7 2 2 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE35820.1 - 5e-09 35.2 1.2 1.1 9.2 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPE35820.1 - 9e-06 25.4 11.6 0.79 9.6 0.3 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPE35820.1 - 6.8e-05 22.7 1.1 2.9 8.3 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPE35820.1 - 0.035 14.5 9.6 5.1 7.7 0.2 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPE35820.1 - 0.051 13.4 0.1 4.3 7.2 0.0 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.1 EPE35820.1 - 0.062 12.4 0.3 9.6 5.2 0.0 3.0 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP CAP PF00188.21 EPE35821.1 - 1e-18 67.9 4.3 1.8e-18 67.2 3.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family NeA_P2 PF12312.3 EPE35821.1 - 0.037 13.2 5.1 0.055 12.7 3.5 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Ank PF00023.25 EPE35822.1 - 1e-29 100.8 2.8 4.3e-07 29.4 0.2 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 EPE35822.1 - 2e-26 92.1 0.1 7.8e-12 45.3 0.1 3.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) HET PF06985.6 EPE35822.1 - 2.5e-23 82.7 5.7 1.1e-19 70.9 0.2 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.1 EPE35822.1 - 8.6e-20 70.3 0.5 4e-06 26.9 0.0 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE35822.1 - 4.4e-19 66.6 0.9 0.0022 18.0 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EPE35822.1 - 1.3e-17 63.7 4.0 1.8e-06 28.2 0.0 4.5 2 1 4 6 6 5 5 Ankyrin repeats (many copies) NACHT PF05729.7 EPE35822.1 - 8.6e-08 32.0 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPE35822.1 - 1.5e-05 25.1 0.0 5.7e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE35822.1 - 0.021 14.9 0.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EPE35822.1 - 0.048 13.1 0.0 0.17 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA-like domain KAP_NTPase PF07693.9 EPE35822.1 - 0.13 11.2 1.8 0.89 8.4 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain NESP55 PF06390.7 EPE35823.1 - 0.19 11.1 3.7 0.37 10.1 2.5 1.5 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) RR_TM4-6 PF06459.7 EPE35823.1 - 1.5 8.6 7.2 3 7.6 5.0 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3337 PF11816.3 EPE35823.1 - 2.8 7.2 8.6 2.5 7.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) Sterol_MT_C PF08498.5 EPE35826.1 - 4e-28 97.1 0.1 6.4e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EPE35826.1 - 1.5e-19 70.2 0.0 3.2e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE35826.1 - 7.2e-18 64.6 0.0 1.1e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE35826.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE35826.1 - 3.5e-13 49.7 0.0 6.4e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE35826.1 - 3.6e-12 46.6 0.0 8.8e-12 45.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 EPE35826.1 - 6.4e-12 45.1 0.1 8.9e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EPE35826.1 - 3e-11 43.8 0.0 7.2e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE35826.1 - 1.5e-10 40.6 0.0 2.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EPE35826.1 - 3.1e-09 36.8 0.0 7.3e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EPE35826.1 - 1.7e-05 24.4 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EPE35826.1 - 3.5e-05 23.2 0.0 6.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EPE35826.1 - 3.7e-05 22.9 0.0 8.5e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EPE35826.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 EPE35826.1 - 0.013 14.7 0.4 0.094 11.8 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase Met_10 PF02475.11 EPE35826.1 - 0.016 14.7 0.0 0.034 13.7 0.0 1.5 2 0 0 2 2 2 0 Met-10+ like-protein PCMT PF01135.14 EPE35826.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EPE35826.1 - 0.024 14.3 0.6 0.039 13.6 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain Sec6 PF06046.8 EPE35826.1 - 0.025 12.7 0.3 0.036 12.1 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 Methyltransf_24 PF13578.1 EPE35826.1 - 0.031 15.0 0.0 0.1 13.4 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain MetW PF07021.7 EPE35826.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.9 EPE35826.1 - 0.091 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB RRM_5 PF13893.1 EPE35827.1 - 3.4e-09 36.4 0.0 5.8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE35827.1 - 6.6e-09 35.2 0.0 1.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE35827.1 - 8.7e-06 25.6 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TSA PF03249.8 EPE35827.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Type specific antigen Complex1_LYR PF05347.10 EPE35828.1 - 1.4e-06 27.9 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPE35828.1 - 3.7e-05 23.8 0.0 5.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF3089 PF11288.3 EPE35828.1 - 0.0071 15.5 0.1 0.0089 15.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Mac PF12464.3 EPE35828.1 - 0.039 13.9 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Maltose acetyltransferase DnaJ PF00226.26 EPE35829.1 - 4e-19 68.0 0.9 4e-19 68.0 0.6 2.5 2 1 0 2 2 2 1 DnaJ domain DUF1682 PF07946.9 EPE35829.1 - 9.8 4.9 22.2 23 3.7 15.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Acetyltransf_1 PF00583.19 EPE35830.1 - 5.4e-14 51.9 0.1 1e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE35830.1 - 2.4e-12 46.9 0.0 4.3e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE35830.1 - 6.8e-11 41.7 0.0 1.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EPE35830.1 - 2.1e-07 31.0 0.0 4.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPE35830.1 - 0.00016 21.8 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPE35830.1 - 0.0023 17.8 0.0 0.0051 16.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPE35830.1 - 0.024 14.5 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE35830.1 - 0.11 12.4 0.0 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase APH PF01636.18 EPE35832.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family ubiquitin PF00240.18 EPE35834.1 - 0.00029 20.1 0.0 0.00048 19.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Menin PF05053.8 EPE35834.1 - 0.038 12.1 1.8 0.049 11.8 1.2 1.1 1 0 0 1 1 1 0 Menin YukD PF08817.5 EPE35834.1 - 0.13 12.7 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Nop PF01798.13 EPE35835.1 - 1.4e-54 183.5 1.5 6.6e-54 181.2 1.0 2.2 1 1 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EPE35835.1 - 1.7e-26 91.7 0.1 3.1e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EPE35835.1 - 6.5e-16 58.2 1.4 6.5e-16 58.2 1.0 3.9 4 0 0 4 4 4 1 NOP5NT (NUC127) domain NuiA PF07924.6 EPE35835.1 - 0.0021 17.9 0.0 0.0048 16.8 0.0 1.6 1 0 0 1 1 1 1 Nuclease A inhibitor-like protein DUF760 PF05542.6 EPE35835.1 - 0.13 12.4 0.1 1.3 9.1 0.0 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF760) vATP-synt_AC39 PF01992.11 EPE35836.1 - 4.2e-117 391.0 0.0 4.7e-117 390.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.17 EPE35837.1 - 9.1e-16 57.4 0.2 1.7e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 SAE2 PF08573.5 EPE35837.1 - 0.21 12.2 1.9 0.23 12.2 0.1 2.0 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Ribosomal_S2 PF00318.15 EPE35838.1 - 2.9e-43 147.5 0.0 9.8e-23 80.4 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 KxDL PF10241.4 EPE35839.1 - 4.1e-30 103.5 1.0 5.4e-30 103.1 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein UL97 PF06734.7 EPE35839.1 - 0.092 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 UL97 Mating_C PF12737.2 EPE35839.1 - 0.48 9.2 10.8 1.5 7.6 0.7 2.4 2 1 0 2 2 2 0 C-terminal domain of homeodomain 1 Dioxygenase_C PF00775.16 EPE35840.1 - 0.084 12.1 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Dioxygenase CTP_transf_1 PF01148.15 EPE35841.1 - 1.9e-15 57.2 9.5 2e-12 47.3 1.5 2.2 1 1 1 2 2 2 2 Cytidylyltransferase family Nup54 PF13874.1 EPE35842.1 - 2e-45 153.9 0.5 3.1e-44 150.0 0.0 2.6 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EPE35842.1 - 5.5e-07 29.8 78.5 0.00012 22.2 27.3 2.9 1 1 1 2 2 2 2 Nucleoporin FG repeat region Phage_Mu_Gam PF07352.7 EPE35842.1 - 0.0033 16.9 0.6 0.0078 15.7 0.4 1.6 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein V-SNARE_C PF12352.3 EPE35842.1 - 0.051 13.6 1.9 5 7.2 0.2 2.8 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Nbl1_Borealin_N PF10444.4 EPE35842.1 - 7.5 5.9 7.5 7.4 6.0 0.5 3.3 2 1 1 3 3 3 0 Nbl1 / Borealin N terminal Acetyltransf_3 PF13302.1 EPE35843.1 - 1e-14 54.8 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPE35843.1 - 5.4e-06 26.4 0.0 7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE35843.1 - 0.0061 16.5 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PIG-H PF10181.4 EPE35844.1 - 8.5e-27 92.5 0.1 1.3e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.15 EPE35845.1 - 3.6e-30 104.4 0.0 2.1e-23 82.7 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase Ras PF00071.17 EPE35846.1 - 6.5e-16 58.1 0.0 2.2e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EPE35846.1 - 4.1e-06 27.2 0.0 6.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE35846.1 - 3.1e-05 23.2 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EPE35846.1 - 0.0046 15.7 0.1 0.0065 15.2 0.1 1.2 1 0 0 1 1 1 1 G-protein alpha subunit SET PF00856.23 EPE35847.1 - 0.0025 18.1 0.0 0.036 14.3 0.0 2.6 2 0 0 2 2 2 1 SET domain Sugar_tr PF00083.19 EPE35848.1 - 3.9e-81 272.9 28.6 4.7e-81 272.6 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE35848.1 - 8.2e-16 57.6 61.3 7.7e-15 54.4 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.18 EPE35849.1 - 2e-07 30.9 0.1 3.3e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE35849.1 - 3.6e-06 26.6 0.0 4.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EPE35849.1 - 0.048 12.3 0.0 0.066 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.20 EPE35849.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain PSI_PsaH PF03244.9 EPE35850.1 - 0.053 12.7 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI 3Beta_HSD PF01073.14 EPE35851.1 - 2.2e-35 121.7 0.0 2.9e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE35851.1 - 6.3e-20 71.6 0.0 1.5e-19 70.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPE35851.1 - 1.1e-09 37.5 0.0 1.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EPE35851.1 - 1.1e-08 34.2 0.0 1.3e-06 27.5 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EPE35851.1 - 6.5e-08 32.7 0.0 9.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPE35851.1 - 1e-06 28.7 0.0 3.1e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE35851.1 - 0.011 15.3 0.0 0.093 12.3 0.0 2.1 2 0 0 2 2 2 0 KR domain NmrA PF05368.8 EPE35851.1 - 0.011 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 EPE35851.1 - 0.02 13.8 0.0 0.047 12.5 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EPE35851.1 - 0.12 11.3 0.0 0.24 10.3 0.0 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase HET PF06985.6 EPE35852.1 - 2e-21 76.6 12.8 4.3e-18 65.8 4.4 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ADH_N PF08240.7 EPE35853.1 - 2.5e-26 91.5 1.9 5.7e-26 90.4 1.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE35853.1 - 2e-07 30.6 0.0 9.6e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EPE35853.1 - 1.1e-05 24.9 1.0 2.7e-05 23.7 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated FANCL_C PF11793.3 EPE35853.1 - 0.042 13.7 0.3 0.079 12.9 0.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain OGFr_N PF04664.8 EPE35855.1 - 8.6e-22 77.5 0.0 1.1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Cu-oxidase_2 PF07731.9 EPE35856.1 - 1.2e-22 79.9 0.1 3e-20 72.1 0.1 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EPE35856.1 - 7.5e-21 74.0 0.9 1.3e-20 73.3 0.1 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EPE35856.1 - 0.012 15.5 0.0 0.15 11.9 0.0 2.7 3 1 0 3 3 3 0 Multicopper oxidase Abhydrolase_6 PF12697.2 EPE35860.1 - 5.1e-18 65.7 0.0 6.5e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE35860.1 - 7.1e-05 22.5 0.0 9e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.2 EPE35861.1 - 1.8e-19 69.8 0.0 7.7e-07 29.3 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPE35861.1 - 2.1e-13 49.3 0.0 0.0013 18.4 0.0 5.7 4 2 2 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EPE35861.1 - 3.2e-12 46.6 0.0 0.003 18.0 0.0 5.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE35861.1 - 9e-12 44.8 0.1 3.1e-06 27.2 0.0 4.5 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE35861.1 - 2.1e-10 39.7 0.0 0.008 16.3 0.0 5.7 5 1 1 6 6 6 2 Ankyrin repeat MFS_1 PF07690.11 EPE35862.1 - 3e-35 121.5 11.1 9.9e-21 73.8 0.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE35862.1 - 3.6e-08 32.4 10.5 1.2e-07 30.6 7.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EPE35862.1 - 7.8e-06 24.5 18.7 3.9e-05 22.2 2.1 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 EPE35862.1 - 0.0012 17.0 9.9 0.0065 14.6 0.4 2.5 3 0 0 3 3 3 2 Transmembrane secretion effector MFS_1_like PF12832.2 EPE35862.1 - 0.0034 17.1 1.6 0.34 10.7 0.1 3.1 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.15 EPE35862.1 - 0.025 12.6 2.9 1.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family BNIP3 PF06553.7 EPE35862.1 - 0.1 11.9 0.5 0.18 11.1 0.3 1.3 1 0 0 1 1 1 0 BNIP3 PADR1 PF08063.7 EPE35863.1 - 0.0049 16.2 4.6 0.47 9.8 0.2 2.3 2 0 0 2 2 2 2 PADR1 (NUC008) domain NAD_binding_6 PF08030.7 EPE35864.1 - 2e-17 63.5 0.0 3.2e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPE35864.1 - 3.6e-14 52.9 13.3 3.6e-14 52.9 9.2 2.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EPE35864.1 - 1.2e-08 34.7 0.1 3.4e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 EPE35864.1 - 0.0016 19.0 0.0 0.95 10.0 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain LETM1 PF07766.8 EPE35865.1 - 1e-11 44.3 0.4 1.4e-09 37.4 0.2 2.2 2 0 0 2 2 2 2 LETM1-like protein RRM_1 PF00076.17 EPE35866.1 - 6.4e-11 41.7 0.0 1.2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE35866.1 - 1.8e-10 40.6 0.0 4.6e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE35866.1 - 7.3e-05 22.5 0.1 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EPE35866.1 - 0.0072 16.0 0.1 0.017 14.8 0.1 1.6 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.6 EPE35866.1 - 0.046 13.5 0.2 0.096 12.5 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif DUF1290 PF06947.7 EPE35867.1 - 0.0046 16.8 0.0 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1290) Chordopox_A13L PF05961.6 EPE35868.1 - 0.026 14.4 0.3 0.051 13.5 0.2 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein SseC PF04888.7 EPE35868.1 - 0.04 13.2 5.1 0.05 12.9 3.6 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Peptidase_U4 PF03419.8 EPE35868.1 - 0.29 10.1 7.7 0.33 9.9 5.3 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF443 PF04276.7 EPE35868.1 - 0.41 10.0 4.5 0.23 10.8 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF443) Glycoprotein_B PF00606.13 EPE35868.1 - 0.87 7.5 6.5 0.98 7.3 4.5 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Antimicrobial10 PF08105.6 EPE35868.1 - 1.2 8.8 3.6 1.9 8.1 0.2 2.6 2 1 1 3 3 3 0 Metchnikowin family DUF1700 PF08006.6 EPE35868.1 - 5.3 6.3 11.6 5.1 6.3 7.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1700) SET PF00856.23 EPE35869.1 - 9.7e-06 25.9 0.0 0.0011 19.2 0.0 2.7 1 1 0 1 1 1 1 SET domain Fungal_trans PF04082.13 EPE35870.1 - 3.9e-11 42.3 0.0 9e-11 41.1 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 EPE35871.1 - 4.8e-88 293.7 48.0 1.5e-45 154.9 10.7 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPE35871.1 - 1.3e-37 129.1 0.0 2.1e-17 63.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EPE35871.1 - 1.4e-26 92.1 0.1 1.2e-23 82.7 0.0 3.0 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 EPE35871.1 - 9.9e-16 57.6 36.1 5.9e-09 35.4 8.3 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EPE35871.1 - 1.6e-06 28.2 0.0 2.2 8.1 0.0 3.4 3 0 0 3 3 3 3 AAA domain AAA_25 PF13481.1 EPE35871.1 - 7.3e-06 25.5 0.4 0.0023 17.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.1 EPE35871.1 - 0.00054 19.9 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_22 PF13401.1 EPE35871.1 - 0.00071 19.7 0.0 0.3 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EPE35871.1 - 0.00098 18.3 0.1 0.017 14.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EPE35871.1 - 0.0048 16.3 0.7 0.32 10.4 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EPE35871.1 - 0.0059 16.6 0.4 0.3 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EPE35871.1 - 0.011 15.2 2.4 0.086 12.3 0.2 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EPE35871.1 - 0.012 15.9 0.1 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPE35871.1 - 0.027 14.2 0.2 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_15 PF13175.1 EPE35871.1 - 0.033 13.2 0.0 5.6 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EPE35871.1 - 0.04 13.8 0.8 0.42 10.5 0.3 2.2 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EPE35871.1 - 0.04 14.4 0.0 3.7 8.0 0.0 3.1 3 0 0 3 3 2 0 Miro-like protein AAA_17 PF13207.1 EPE35871.1 - 0.043 14.6 0.0 1.8 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EPE35871.1 - 0.043 13.0 0.0 0.37 9.9 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 EPE35871.1 - 0.045 13.4 0.0 10 5.7 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EPE35871.1 - 0.05 13.8 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EPE35871.1 - 0.053 13.1 0.7 5.2 6.7 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EPE35871.1 - 0.07 12.6 0.4 1.6 8.2 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EPE35871.1 - 0.12 12.2 0.0 1.1 9.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EPE35871.1 - 0.16 11.6 0.2 2 8.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 EPE35871.1 - 0.18 10.8 0.5 12 4.8 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin Pyridoxal_deC PF00282.14 EPE35872.1 - 1.5e-77 260.5 0.0 3e-77 259.6 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EPE35872.1 - 2e-05 23.5 0.0 3.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPE35872.1 - 7.9e-05 21.9 0.0 8.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase HTH_23 PF13384.1 EPE35873.1 - 0.066 12.8 1.6 0.19 11.3 0.0 2.5 3 0 0 3 3 3 0 Homeodomain-like domain DUF4035 PF13227.1 EPE35874.1 - 0.11 11.9 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) TAP35_44 PF07265.6 EPE35874.1 - 0.13 12.0 0.1 0.15 11.8 0.1 1.0 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 AMMECR1 PF01871.12 EPE35875.1 - 8.6e-43 145.4 0.0 1.5e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 AMMECR1 Pol_alpha_B_N PF08418.5 EPE35875.1 - 0.8 9.1 6.8 1 8.8 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ras PF00071.17 EPE35876.1 - 4.5e-39 133.4 0.0 6.2e-38 129.7 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EPE35876.1 - 1.7e-12 47.9 0.0 3.4e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPE35876.1 - 0.00036 20.4 0.0 0.00056 19.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EPE35876.1 - 0.0016 17.6 0.0 0.0093 15.2 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPE35876.1 - 0.05 13.0 0.0 2.4 7.5 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PRK PF00485.13 EPE35876.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Suf PF05843.9 EPE35877.1 - 1.2e-86 290.9 5.7 1.4e-86 290.7 0.0 3.5 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EPE35877.1 - 0.0001 22.8 0.2 0.0091 16.6 0.1 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE35877.1 - 0.00021 21.6 0.6 0.048 14.3 0.1 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPE35877.1 - 0.00029 21.0 0.0 0.08 13.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat HAT PF02184.11 EPE35877.1 - 0.00096 18.8 0.2 0.14 11.9 0.1 2.5 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat ASF1_hist_chap PF04729.8 EPE35878.1 - 2.5e-67 225.3 0.0 3.3e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone adh_short_C2 PF13561.1 EPE35879.1 - 9.5e-29 100.8 0.1 1.1e-28 100.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE35879.1 - 2.1e-27 96.0 0.3 2.6e-27 95.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE35879.1 - 1.6e-14 53.9 0.1 2.2e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Pkinase_Tyr PF07714.12 EPE35880.1 - 0.14 11.2 0.0 0.72 8.8 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase Glyco_hydro_16 PF00722.16 EPE35882.1 - 1e-10 41.2 2.6 2e-10 40.2 1.4 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glyco_tranf_2_3 PF13641.1 EPE35883.1 - 1.7e-05 24.7 0.0 3.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EPE35883.1 - 0.005 16.1 0.0 0.012 14.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EPE35883.1 - 0.033 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 VHS PF00790.14 EPE35884.1 - 3.3e-47 159.6 0.0 1.1e-46 157.9 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EPE35884.1 - 1.6e-25 89.0 0.8 4.5e-25 87.5 0.6 1.8 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 EPE35884.1 - 5.9e-20 71.6 0.3 1.9e-19 70.0 0.1 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain DUF367 PF04034.8 EPE35885.1 - 8.4e-49 164.4 0.1 1.2e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EPE35885.1 - 1.1e-12 47.2 1.1 2.5e-12 46.1 0.8 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF2407_C PF13373.1 EPE35885.1 - 3 7.7 4.3 0.96 9.3 0.6 1.8 2 0 0 2 2 2 0 DUF2407 C-terminal domain FAD_binding_4 PF01565.18 EPE35886.1 - 2.5e-23 82.0 1.7 4.2e-23 81.3 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE35886.1 - 0.0012 18.7 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 EPE35887.1 - 7.1e-15 54.5 35.1 7.1e-15 54.5 24.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.6 EPE35887.1 - 0.21 10.8 3.4 1.7 7.8 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Methyltransf_23 PF13489.1 EPE35888.1 - 2.3e-08 33.8 0.0 4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE35888.1 - 7.7e-07 29.5 0.0 2.5e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE35888.1 - 1e-05 25.1 0.0 2.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE35888.1 - 0.00021 21.8 0.0 0.00084 19.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 EPE35888.1 - 0.00046 19.5 0.0 0.02 14.1 0.0 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.7 EPE35888.1 - 0.01 16.3 0.1 0.034 14.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Cellulase PF00150.13 EPE35889.1 - 5.1e-10 39.0 0.2 9.1e-10 38.1 0.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-RanBP PF00641.13 EPE35890.1 - 0.0057 15.7 2.7 0.0057 15.7 1.9 2.1 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others AF-4 PF05110.8 EPE35891.1 - 9.6 3.9 6.5 13 3.4 4.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MFS_1 PF07690.11 EPE35892.1 - 6.7e-24 84.2 24.8 6.7e-24 84.2 17.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MscS_TM PF12794.2 EPE35892.1 - 0.028 13.0 0.1 0.055 12.0 0.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Zn_clus PF00172.13 EPE35893.1 - 2.6e-08 33.6 9.2 6.5e-08 32.3 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lgl_C PF08596.5 EPE35895.1 - 8.9e-116 386.5 0.0 3.1e-115 384.7 0.0 1.9 3 0 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EPE35895.1 - 5.7e-05 22.8 0.3 0.96 9.4 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat PP28 PF10252.4 EPE35897.1 - 5e-30 103.3 17.4 5e-30 103.3 12.0 3.1 3 0 0 3 3 3 2 Casein kinase substrate phosphoprotein PP28 PAS_9 PF13426.1 EPE35898.1 - 7.1e-26 90.6 0.0 1.8e-13 50.7 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EPE35898.1 - 2e-14 53.4 0.0 7.3e-10 38.8 0.0 3.6 3 0 0 3 3 3 2 PAS fold GATA PF00320.22 EPE35898.1 - 2.2e-14 52.4 8.1 5e-14 51.3 5.6 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 EPE35898.1 - 1.5e-11 44.0 0.0 0.0003 20.5 0.0 3.7 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.1 EPE35898.1 - 3.4e-11 43.0 0.0 0.00021 21.2 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EPE35898.1 - 5e-07 29.7 0.0 0.038 14.0 0.0 3.5 3 1 0 3 3 3 2 PAS fold YadA_anchor PF03895.10 EPE35898.1 - 0.021 14.8 1.8 0.028 14.4 0.1 2.2 2 0 0 2 2 2 0 YadA-like C-terminal region DMPK_coil PF08826.5 EPE35898.1 - 0.047 13.5 0.9 0.11 12.4 0.6 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like HEAT PF02985.17 EPE35899.1 - 6.1e-21 72.5 6.1 0.0062 16.5 0.1 9.5 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 EPE35899.1 - 1.1e-20 73.7 12.2 3.9e-08 33.4 0.0 8.9 4 3 3 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 EPE35899.1 - 2.5e-18 65.9 18.0 3.1e-09 37.0 0.2 8.9 8 2 2 10 10 10 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPE35899.1 - 1.2e-12 48.0 0.2 0.014 15.7 0.0 6.2 3 2 3 6 6 6 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EPE35899.1 - 3e-08 33.3 2.3 0.001 18.5 0.2 4.2 4 1 1 5 5 5 2 CLASP N terminal RIX1 PF08167.7 EPE35899.1 - 3.3e-08 33.3 0.4 0.00018 21.2 0.1 4.2 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EPE35899.1 - 1.4e-07 30.5 0.7 1.6e-05 23.8 0.0 3.3 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Proteasom_PSMB PF10508.4 EPE35899.1 - 0.00029 19.2 1.5 0.011 14.0 0.2 2.9 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 EPE35899.1 - 0.00033 19.1 2.2 0.03 12.6 0.1 3.2 3 1 0 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.2 EPE35899.1 - 0.0012 18.6 3.2 0.87 9.4 0.2 3.7 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 TAN PF11640.3 EPE35899.1 - 0.009 15.7 0.1 0.23 11.1 0.1 3.3 3 1 0 3 3 3 1 Telomere-length maintenance and DNA damage repair IBN_N PF03810.14 EPE35899.1 - 0.026 14.4 0.0 0.32 10.9 0.0 3.1 2 0 0 2 2 2 0 Importin-beta N-terminal domain Arm PF00514.18 EPE35899.1 - 0.028 14.2 13.2 0.059 13.2 0.1 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 EPE35899.1 - 0.2 10.7 4.6 0.29 10.2 0.2 2.9 2 2 0 2 2 2 0 V-ATPase subunit H DUF3385 PF11865.3 EPE35899.1 - 0.94 9.3 6.1 85 3.0 0.1 5.1 4 2 0 5 5 5 0 Domain of unknown function (DUF3385) CBS PF00571.23 EPE35900.1 - 1.3e-17 63.2 0.4 4.2e-06 26.4 0.0 4.8 5 0 0 5 5 5 4 CBS domain Dmrt1 PF12374.3 EPE35900.1 - 3.2 8.1 10.3 1.9 8.9 2.1 3.6 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 Glyco_hydro_76 PF03663.9 EPE35901.1 - 1.5e-154 514.8 18.8 2e-154 514.4 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EPE35901.1 - 2.8 6.8 15.9 0.2 10.6 0.5 3.6 4 0 0 4 4 4 0 Glycosyl Hydrolase Family 88 Saccharop_dh PF03435.13 EPE35902.1 - 2e-104 349.6 0.0 1.4e-103 346.9 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EPE35902.1 - 6.4e-08 32.7 0.2 1.1e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EPE35902.1 - 0.00076 19.5 0.4 0.0013 18.7 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EPE35902.1 - 0.025 14.8 0.1 0.064 13.5 0.1 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EPE35903.1 - 1.6e-14 54.1 0.3 2.8e-14 53.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE35903.1 - 9.9e-06 25.3 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE35903.1 - 0.00039 20.2 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPE35903.1 - 0.0029 17.6 0.0 0.014 15.3 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPE35903.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 EPE35905.1 - 2e-40 138.5 37.5 3.1e-40 137.9 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE35905.1 - 1e-09 37.4 22.5 5.9e-09 35.0 10.7 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter DUF2178 PF09946.4 EPE35905.1 - 0.012 15.3 1.1 0.053 13.2 0.8 2.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) GFA PF04828.9 EPE35906.1 - 1.9e-20 72.5 12.6 6.5e-11 42.0 0.0 2.7 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 EPE35906.1 - 0.00027 20.6 0.9 0.04 13.7 0.1 3.0 2 0 0 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like NapB PF03892.9 EPE35906.1 - 0.051 13.2 2.8 0.088 12.4 1.9 1.3 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Herpes_UL49_1 PF03117.9 EPE35906.1 - 0.28 10.2 3.7 0.42 9.6 0.7 2.1 2 0 0 2 2 2 0 UL49 family ubiquitin PF00240.18 EPE35907.1 - 3.9e-09 35.7 0.1 8.1e-09 34.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S2 PF00318.15 EPE35908.1 - 5.1e-50 169.6 0.0 8.4e-50 168.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S2 ArfGap PF01412.13 EPE35908.1 - 0.039 13.7 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf CBS PF00571.23 EPE35909.1 - 1.4e-41 139.9 9.5 4.8e-11 42.2 0.0 5.1 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EPE35909.1 - 9.4e-09 34.8 0.0 3.6e-08 32.9 0.0 2.1 2 1 0 2 2 2 1 PB1 domain zf-H2C2_2 PF13465.1 EPE35910.1 - 1.1e-07 31.7 15.2 0.00043 20.4 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPE35910.1 - 5.4e-06 26.4 23.5 0.00045 20.3 4.8 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE35910.1 - 0.025 14.9 21.8 0.28 11.6 4.3 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPE35910.1 - 4.6 7.2 9.5 0.72 9.8 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DAO PF01266.19 EPE35913.1 - 3.3e-49 167.7 0.0 4.3e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE35913.1 - 4.1e-08 32.4 0.3 1e-07 31.1 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EPE35913.1 - 5.8e-07 28.9 0.1 2.4e-06 26.9 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPE35913.1 - 3.1e-05 23.9 0.1 0.00025 20.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPE35913.1 - 0.003 16.4 0.0 0.011 14.5 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EPE35913.1 - 0.011 16.1 0.2 0.033 14.5 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EPE35913.1 - 0.012 15.2 0.3 0.024 14.3 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EPE35913.1 - 0.012 15.6 0.2 0.04 13.9 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EPE35913.1 - 0.029 12.8 0.4 0.046 12.1 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EPE35913.1 - 0.12 11.2 0.1 0.21 10.4 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Fungal_trans PF04082.13 EPE35914.1 - 4.8e-27 94.4 0.0 8.8e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE35914.1 - 3.4e-07 30.0 6.7 6.5e-07 29.1 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 EPE35916.1 - 1.4e-72 243.9 0.0 1.6e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 EPE35917.1 - 7.7e-10 38.9 0.0 8.9e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE35917.1 - 2.7e-05 23.9 0.0 3.3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPE35917.1 - 4.8e-05 23.2 0.0 5.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Mucin PF01456.12 EPE35918.1 - 0.021 14.5 9.6 0.025 14.3 6.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4560 PF15118.1 EPE35920.1 - 0.017 14.8 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4560) Ripply PF14998.1 EPE35920.1 - 0.075 13.1 0.6 0.4 10.8 0.1 2.1 1 1 0 2 2 2 0 Transcription Regulator Antifungal_pept PF11410.3 EPE35920.1 - 0.76 9.9 4.1 0.34 11.0 0.6 2.1 2 0 0 2 2 2 0 Antifungal peptide MFS_1 PF07690.11 EPE35921.1 - 2.1e-43 148.3 35.1 2.1e-43 148.3 24.3 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE35921.1 - 6.7e-20 71.0 23.3 1.6e-19 69.8 16.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EPE35921.1 - 8.8e-08 30.7 5.4 8.8e-08 30.7 3.8 1.5 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LCD1 PF09798.4 EPE35921.1 - 0.44 8.4 0.0 0.63 7.9 0.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein PAP2 PF01569.16 EPE35921.1 - 2.9 7.5 14.1 0.1 12.3 3.4 2.9 2 1 0 2 2 2 0 PAP2 superfamily MFS_2 PF13347.1 EPE35921.1 - 4.6 5.5 37.6 0.037 12.4 3.8 4.0 3 1 0 4 4 4 0 MFS/sugar transport protein Gly-zipper_OmpA PF13436.1 EPE35921.1 - 6.2 6.5 7.5 14 5.3 0.1 2.3 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain SLAC1 PF03595.12 EPE35923.1 - 3.7e-72 242.7 39.1 5.3e-72 242.2 27.1 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3325 PF11804.3 EPE35923.1 - 0.032 14.1 3.6 0.25 11.2 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) SOG2 PF10428.4 EPE35924.1 - 2.9e-90 303.0 1.6 2.9e-90 303.0 1.1 3.2 4 0 0 4 4 4 1 RAM signalling pathway protein LRR_4 PF12799.2 EPE35924.1 - 2e-19 68.7 6.6 3.3e-08 32.9 0.9 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE35924.1 - 8e-16 57.5 4.6 1.4e-10 40.7 0.5 2.8 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EPE35924.1 - 6e-11 40.7 5.1 0.24 11.5 0.1 6.0 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EPE35924.1 - 8.6e-07 28.1 1.8 23 5.8 0.1 5.9 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EPE35924.1 - 0.00039 20.1 3.1 32 5.0 0.1 5.5 5 0 0 5 5 5 0 Leucine Rich repeat Actin PF00022.14 EPE35925.1 - 2.1e-132 441.3 0.0 2.3e-132 441.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPE35925.1 - 0.0087 14.6 0.0 0.06 11.9 0.0 2.2 1 1 0 1 1 1 1 MreB/Mbl protein ApbA_C PF08546.6 EPE35926.1 - 4.4e-27 94.5 0.0 8.9e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EPE35926.1 - 1.6e-26 92.5 0.0 2.1e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EPE35926.1 - 0.0015 18.5 0.3 0.0031 17.6 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EPE35926.1 - 0.016 15.0 1.2 0.033 14.0 0.8 1.5 1 0 0 1 1 1 0 ThiF family Hyd_WA PF06462.7 EPE35927.1 - 0.019 14.5 0.7 0.055 13.1 0.0 2.0 2 0 0 2 2 2 0 Propeller Cu-binding_MopE PF11617.3 EPE35927.1 - 0.14 11.9 2.0 1.7 8.5 0.3 2.4 2 0 0 2 2 2 0 Protein metal binding site XH PF03469.9 EPE35928.1 - 0.00046 19.8 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 XH domain Pyr_redox_2 PF07992.9 EPE35930.1 - 3.4e-40 138.0 0.8 5.6e-40 137.3 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EPE35930.1 - 3.4e-34 117.1 0.7 3.2e-33 114.0 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EPE35930.1 - 1.4e-18 67.0 0.5 9.8e-18 64.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE35930.1 - 6.1e-09 36.2 0.1 1.7e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPE35930.1 - 2.7e-07 29.8 0.0 1.3e-05 24.2 0.0 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EPE35930.1 - 0.0025 16.3 4.2 0.5 8.7 0.0 3.1 2 1 0 3 3 3 2 HI0933-like protein 2-Hacid_dh_C PF02826.14 EPE35930.1 - 0.0064 15.6 0.1 0.11 11.5 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EPE35930.1 - 0.0085 15.6 0.4 0.56 9.7 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EPE35930.1 - 0.042 13.5 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EPE35930.1 - 0.043 12.9 0.2 0.11 11.6 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE35930.1 - 0.045 12.5 2.9 0.29 9.9 0.6 2.6 3 0 0 3 3 3 0 FAD binding domain DAO PF01266.19 EPE35930.1 - 0.048 12.5 0.2 0.048 12.5 0.1 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pro-kuma_activ PF09286.6 EPE35931.1 - 2e-39 134.8 1.7 3.3e-39 134.1 1.2 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EPE35931.1 - 1.1e-09 37.8 0.1 1.7e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.17 EPE35932.1 - 1.2e-41 142.7 3.8 1.7e-41 142.2 2.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EPE35932.1 - 7.9e-09 35.9 0.0 1.6e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Tcp11 PF05794.8 EPE35933.1 - 2.4e-60 204.5 0.0 4.8e-60 203.5 0.0 1.5 1 0 0 1 1 1 1 T-complex protein 11 IFRD PF05004.8 EPE35934.1 - 7.1e-40 136.9 2.5 9.4e-40 136.5 1.8 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 EPE35934.1 - 0.0015 18.7 0.2 0.026 14.7 0.0 2.7 1 1 2 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EPE35934.1 - 0.043 14.3 0.7 8 7.0 0.1 3.2 2 1 1 3 3 3 0 HEAT-like repeat Corona_nucleoca PF00937.13 EPE35934.1 - 1.2 7.9 6.9 0.15 10.9 1.9 1.5 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein FHA PF00498.21 EPE35935.1 - 2e-13 50.2 0.0 4.1e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain DUF3602 PF12223.3 EPE35938.1 - 6.2e-19 68.1 18.3 1.1e-14 54.5 1.5 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) RRM_1 PF00076.17 EPE35944.1 - 1.2e-13 50.5 0.0 3.7e-13 48.9 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE35944.1 - 6.2e-09 35.7 0.0 1.6e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE35944.1 - 7.7e-07 28.8 0.2 2e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPE35944.1 - 0.1 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif P2 PF07194.6 EPE35944.1 - 2.1 8.2 11.4 2.3 8.1 1.8 2.8 2 0 0 2 2 2 0 P2 response regulator binding domain SMN PF06003.7 EPE35945.1 - 0.28 10.2 11.4 1.3 8.0 0.1 2.9 2 1 0 3 3 3 0 Survival motor neuron protein (SMN) Cu_bind_like PF02298.12 EPE35947.1 - 0.0099 15.6 0.1 0.047 13.4 0.1 1.9 1 1 0 1 1 1 1 Plastocyanin-like domain 4F5 PF04419.9 EPE35948.1 - 6.9e-09 36.3 9.3 6.9e-09 36.3 6.4 2.1 3 0 0 3 3 3 1 4F5 protein family Borrelia_REV PF03978.8 EPE35948.1 - 0.14 11.8 1.2 0.15 11.7 0.8 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Caps_synth_CapC PF14102.1 EPE35949.1 - 0.2 11.8 5.7 0.036 14.1 1.2 1.7 2 0 0 2 2 2 0 Capsule biosynthesis CapC DUF4282 PF14110.1 EPE35949.1 - 0.48 10.6 14.0 0.07 13.3 4.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Guanylate_kin PF00625.16 EPE35950.1 - 2e-55 187.0 0.0 2.3e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 EPE35950.1 - 9.7e-06 25.9 0.4 8e-05 22.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPE35950.1 - 3.8e-05 23.5 0.0 0.00021 21.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE35950.1 - 5.4e-05 23.9 0.1 0.00014 22.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPE35950.1 - 0.00066 19.8 0.0 0.0088 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EPE35950.1 - 0.003 17.4 0.0 0.004 17.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EPE35950.1 - 0.0057 16.6 0.1 0.034 14.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EPE35950.1 - 0.0077 15.4 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF1895 PF08988.5 EPE35950.1 - 0.011 15.6 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) Arch_ATPase PF01637.13 EPE35950.1 - 0.016 14.9 0.4 0.11 12.1 0.3 2.0 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 EPE35950.1 - 0.048 13.6 0.0 0.31 10.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EPE35950.1 - 0.063 12.7 0.1 0.33 10.3 0.1 1.9 1 1 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 EPE35950.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPE35950.1 - 0.13 12.6 0.1 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA PF00004.24 EPE35950.1 - 0.18 12.0 0.7 0.92 9.7 0.0 2.1 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 EPE35951.1 - 1.6e-111 371.8 0.3 1.9e-111 371.6 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EPE35951.1 - 5.4e-07 29.5 0.0 1e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EPE35951.1 - 3.7e-06 26.2 0.0 6.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EPE35951.1 - 4.1e-05 22.8 0.0 7.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EPE35951.1 - 0.00051 19.8 0.4 1.2 8.9 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EPE35951.1 - 0.00077 18.9 0.2 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EPE35951.1 - 0.0033 16.9 0.1 0.0034 16.8 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EPE35951.1 - 0.01 16.1 0.2 0.016 15.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 EPE35951.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EPE35951.1 - 0.015 15.6 0.0 0.026 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EPE35951.1 - 0.025 13.4 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Gtr1_RagA PF04670.7 EPE35951.1 - 0.027 13.5 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region T2SE PF00437.15 EPE35951.1 - 0.031 13.1 0.0 0.075 11.9 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EPE35951.1 - 0.035 13.5 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EPE35951.1 - 0.041 13.8 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.27 EPE35952.1 - 8.3e-30 101.5 13.7 4.6e-12 45.3 0.5 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Ribosomal_L32p PF01783.18 EPE35952.1 - 3.4e-13 49.5 2.1 6.9e-13 48.5 1.4 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family eIF2A PF08662.6 EPE35952.1 - 2.3e-05 24.1 0.2 0.013 15.2 0.0 3.5 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EPE35952.1 - 0.0021 16.4 0.1 0.015 13.5 0.0 1.8 1 1 1 2 2 2 1 Cytochrome D1 heme domain RecR PF02132.10 EPE35952.1 - 0.0042 16.4 0.8 0.0086 15.4 0.5 1.5 1 0 0 1 1 1 1 RecR protein Nbas_N PF15492.1 EPE35952.1 - 0.0043 16.1 0.3 0.46 9.5 0.0 3.2 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal RimM PF01782.13 EPE35952.1 - 0.043 13.7 0.1 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 RimM N-terminal domain Gmad1 PF10647.4 EPE35952.1 - 0.045 13.1 0.1 0.53 9.6 0.0 2.2 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain DUF1513 PF07433.6 EPE35952.1 - 0.051 12.4 0.2 0.65 8.8 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) Coatomer_WDAD PF04053.9 EPE35952.1 - 0.057 12.2 0.0 0.12 11.1 0.0 1.6 1 1 0 1 1 1 0 Coatomer WD associated region Atg14 PF10186.4 EPE35952.1 - 0.15 10.9 0.1 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PAP1 PF08601.5 EPE35953.1 - 0.27 10.8 15.4 0.34 10.5 10.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF4614 PF15391.1 EPE35953.1 - 0.97 9.1 12.4 1.4 8.6 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.4 EPE35953.1 - 4.1 5.5 14.9 4.6 5.4 10.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 EPE35953.1 - 9.2 5.6 14.0 12 5.3 9.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ydc2-catalyt PF09159.5 EPE35954.1 - 3.6e-77 259.5 0.1 4.6e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EPE35954.1 - 2.7e-08 33.8 0.1 0.00082 19.2 0.0 3.2 2 1 0 2 2 2 2 Poxvirus A22 protein SAP PF02037.22 EPE35954.1 - 1.3e-06 27.7 1.8 1.9e-06 27.2 0.1 2.1 2 0 0 2 2 2 1 SAP domain Tissue_fac PF01108.12 EPE35954.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Tissue factor TpcC PF12642.2 EPE35954.1 - 0.044 13.3 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 Conjugative transposon protein TcpC CFEM PF05730.6 EPE35955.1 - 2.5e-10 39.9 12.5 2.8e-10 39.8 7.1 2.0 2 0 0 2 2 2 1 CFEM domain Sporozoite_P67 PF05642.6 EPE35955.1 - 1 7.1 4.7 1.1 6.9 3.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Aa_trans PF01490.13 EPE35956.1 - 1.3e-71 241.2 33.5 1.6e-71 240.9 23.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YrhC PF14143.1 EPE35956.1 - 0.062 13.2 4.3 0.53 10.2 0.2 3.1 2 0 0 2 2 2 0 YrhC-like protein Ras PF00071.17 EPE35959.1 - 1.4e-55 187.1 0.0 1.6e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE35959.1 - 1e-15 58.2 0.0 1.7e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE35959.1 - 4.8e-07 29.1 0.0 7.8e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPE35959.1 - 0.0012 18.2 0.0 0.0056 16.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EPE35959.1 - 0.0018 17.5 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPE35959.1 - 0.027 13.6 0.0 0.041 13.0 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EPE35959.1 - 0.13 11.7 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KOW PF00467.24 EPE35960.1 - 1.3e-07 31.0 3.8 3.3e-07 29.7 2.6 1.7 1 0 0 1 1 1 1 KOW motif IKI3 PF04762.7 EPE35961.1 - 0 1105.0 0.0 0 1104.7 0.0 1.1 1 0 0 1 1 1 1 IKI3 family DUF3984 PF13136.1 EPE35962.1 - 3.9e-68 230.0 9.9 3.9e-68 230.0 6.9 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) TPR_12 PF13424.1 EPE35963.1 - 1.4e-79 262.0 30.3 6.1e-17 61.3 0.4 4.8 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 EPE35963.1 - 9e-50 165.2 12.9 6.9e-07 28.9 0.1 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 EPE35963.1 - 7.3e-30 101.3 17.0 0.0003 20.2 0.2 7.8 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 EPE35963.1 - 3.8e-29 98.1 11.1 0.00028 20.4 0.0 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 EPE35963.1 - 5.4e-24 83.6 10.9 2.7e-08 33.3 0.3 5.2 3 2 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 EPE35963.1 - 7.5e-24 81.6 17.1 0.002 17.8 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat HET PF06985.6 EPE35963.1 - 2.9e-20 72.8 5.1 1.3e-16 61.0 0.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_8 PF13181.1 EPE35963.1 - 1.5e-19 68.1 16.8 0.014 15.1 0.0 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 EPE35963.1 - 2.8e-18 66.0 7.9 4.2e-05 24.0 0.0 5.6 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 EPE35963.1 - 4.4e-18 64.1 14.4 0.024 15.2 0.1 8.0 7 1 1 8 8 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EPE35963.1 - 2.9e-12 45.7 7.5 0.36 11.1 0.0 8.5 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPE35963.1 - 1.2e-10 41.0 16.7 0.29 11.6 0.2 8.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_4 PF07721.9 EPE35963.1 - 6.9e-10 38.3 0.0 0.86 10.2 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat NB-ARC PF00931.17 EPE35963.1 - 1.1e-09 37.6 0.0 1.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 EPE35963.1 - 2.5e-08 34.1 13.8 0.066 13.5 0.6 6.0 3 2 4 7 7 7 5 Tetratricopeptide repeat Tcf25 PF04910.9 EPE35963.1 - 4.3e-06 25.9 0.0 0.67 8.8 0.0 3.7 3 1 1 4 4 4 2 Transcriptional repressor TCF25 Arch_ATPase PF01637.13 EPE35963.1 - 1.5e-05 24.8 0.1 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase PPR PF01535.15 EPE35963.1 - 1.5e-05 24.6 5.8 0.5 10.4 0.0 6.5 7 0 0 7 7 7 1 PPR repeat AAA_16 PF13191.1 EPE35963.1 - 2.4e-05 24.4 0.0 5.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain SNAP PF14938.1 EPE35963.1 - 0.00064 18.9 1.0 0.45 9.6 0.0 3.2 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP DUF2225 PF09986.4 EPE35963.1 - 0.0007 19.1 3.8 5.9 6.2 0.0 4.1 1 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Apc3 PF12895.2 EPE35963.1 - 0.00089 19.3 1.2 0.32 11.1 0.0 3.3 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.7 EPE35963.1 - 0.014 15.0 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TPR_5 PF12688.2 EPE35963.1 - 0.022 14.7 6.8 0.17 11.9 0.1 4.3 3 2 1 4 4 4 0 Tetratrico peptide repeat KGK PF08872.5 EPE35963.1 - 0.032 14.3 0.1 0.087 12.9 0.1 1.8 1 0 0 1 1 1 0 KGK domain AAA_22 PF13401.1 EPE35963.1 - 0.038 14.1 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_21 PF09976.4 EPE35963.1 - 4.1 7.3 6.5 54 3.7 0.0 4.4 2 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EPE35963.1 - 4.7 7.1 9.0 0.55 10.1 0.1 3.5 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain Asp PF00026.18 EPE35964.1 - 8.9e-66 222.2 4.3 8.9e-66 222.2 3.0 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPE35964.1 - 1.8e-08 34.5 0.6 1.8e-08 34.5 0.4 3.0 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EPE35964.1 - 0.046 13.2 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EPE35964.1 - 0.048 14.1 5.1 0.2 12.1 0.2 3.6 3 2 0 3 3 3 0 Aspartyl protease F-box PF00646.28 EPE35965.1 - 1.5e-06 27.6 0.1 4e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPE35965.1 - 0.00019 21.1 0.0 0.00041 20.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EPE35965.1 - 0.024 14.5 0.3 0.077 12.9 0.1 1.9 2 0 0 2 2 2 0 PRANC domain Kelch_5 PF13854.1 EPE35966.1 - 0.062 13.2 0.1 0.062 13.2 0.1 4.8 5 1 0 5 5 5 0 Kelch motif Kelch_6 PF13964.1 EPE35966.1 - 0.074 13.2 8.0 7.2 6.9 0.1 5.0 5 1 0 5 5 5 0 Kelch motif Oxidored_q5_N PF01059.12 EPE35967.1 - 0.044 13.6 3.5 0.055 13.3 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus HhH-GPD PF00730.20 EPE35968.1 - 7.1e-16 58.4 0.0 1.4e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Anp1 PF03452.9 EPE35969.1 - 2.6e-111 371.1 0.0 3.1e-111 370.8 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EPE35969.1 - 0.034 13.8 0.1 0.26 10.9 0.2 2.2 1 1 1 2 2 2 0 Glycosyl transferase family 2 UCR_14kD PF02271.11 EPE35970.1 - 1.3e-43 146.9 0.3 1.5e-43 146.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 EPE35971.1 - 5.3e-69 227.9 3.7 1.3e-24 85.7 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Arabinose_trans PF04602.7 EPE35972.1 - 0.13 10.4 0.0 0.15 10.2 0.0 1.0 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein ABC1 PF03109.11 EPE35973.1 - 4.2e-31 107.3 0.0 8e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family AD PF09793.4 EPE35973.1 - 0.032 14.0 0.0 0.083 12.7 0.0 1.7 1 0 0 1 1 1 0 Anticodon-binding domain tRNA-synt_His PF13393.1 EPE35974.1 - 7.2e-40 136.9 0.0 8.9e-39 133.3 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EPE35974.1 - 4.4e-17 62.2 0.0 7.5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPE35974.1 - 4.8e-08 32.8 0.0 9.5e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EPE35974.1 - 2.7e-05 23.1 0.0 0.0018 17.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EPE35974.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Pkinase PF00069.20 EPE35977.1 - 3.5e-06 26.3 0.0 6.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EPE35977.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE35977.1 - 0.04 13.6 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EPE35977.1 - 0.092 11.7 0.0 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 EPE35978.1 - 7.5e-70 235.0 0.0 1.6e-69 233.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE35978.1 - 1.9e-47 161.5 0.0 3.2e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE35978.1 - 0.00013 21.0 0.0 0.00033 19.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like V-ATPase_H_N PF03224.9 EPE35978.1 - 0.027 13.5 0.4 3.4 6.7 0.0 2.4 2 0 0 2 2 2 0 V-ATPase subunit H CLASP_N PF12348.3 EPE35978.1 - 0.18 11.1 1.9 0.57 9.5 0.2 2.1 2 0 0 2 2 2 0 CLASP N terminal Herpes_capsid PF06112.6 EPE35979.1 - 5.9 6.9 10.1 17 5.4 7.0 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Mur_ligase_M PF08245.7 EPE35980.1 - 7.6e-07 29.3 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain SPATIAL PF15256.1 EPE35980.1 - 0.0031 17.6 0.1 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 SPATIAL AAA_17 PF13207.1 EPE35982.1 - 0.00018 22.3 0.1 0.0005 20.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EPE35982.1 - 0.0024 17.4 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EPE35982.1 - 0.0027 17.9 0.1 0.0066 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EPE35982.1 - 0.0083 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.7 EPE35982.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 EPE35982.1 - 0.012 14.4 0.0 0.031 13.1 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EPE35982.1 - 0.015 14.9 0.3 0.026 14.2 0.2 1.3 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.4 EPE35982.1 - 0.016 14.1 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EPE35982.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPE35982.1 - 0.026 14.4 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPE35982.1 - 0.028 14.4 0.0 0.048 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EPE35982.1 - 0.037 13.7 0.5 0.082 12.6 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EPE35982.1 - 0.042 13.2 0.1 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain Viral_helicase1 PF01443.13 EPE35982.1 - 0.064 12.7 0.1 0.089 12.3 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.5 EPE35982.1 - 0.084 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ArgK PF03308.11 EPE35982.1 - 0.088 11.5 0.3 2.5 6.7 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AAA PF00004.24 EPE35982.1 - 0.096 12.8 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EPE35982.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EPE35982.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EPE35982.1 - 0.12 12.0 0.2 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 EPE35982.1 - 0.13 11.7 0.6 0.19 11.1 0.4 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PRELI PF04707.9 EPE35983.1 - 6.4e-42 142.7 0.6 7.8e-42 142.5 0.4 1.1 1 0 0 1 1 1 1 PRELI-like family Rpn3_C PF08375.6 EPE35984.1 - 3.4e-25 88.2 1.5 9.6e-25 86.7 1.1 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EPE35984.1 - 8.4e-20 71.0 0.9 5.2e-19 68.5 0.1 2.5 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 EPE35984.1 - 0.0095 15.7 0.2 0.028 14.3 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EPE35984.1 - 0.13 12.0 0.8 1 9.1 0.6 2.2 1 1 0 1 1 1 0 COP9 signalosome, subunit CSN8 MOZ_SAS PF01853.13 EPE35985.1 - 2e-31 108.7 0.0 1.6e-29 102.5 0.0 2.5 1 1 0 1 1 1 1 MOZ/SAS family RPAP3_C PF13877.1 EPE35987.1 - 0.023 14.6 0.1 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Zn_clus PF00172.13 EPE35988.1 - 2.4e-06 27.3 4.7 6.5e-06 25.9 3.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1220 PF06758.8 EPE35988.1 - 0.018 14.8 1.1 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF1220) Zn_clus PF00172.13 EPE35989.1 - 0.0036 17.1 11.5 0.0077 16.1 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HpcH_HpaI PF03328.9 EPE35990.1 - 6.8e-26 90.5 0.0 8e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MIP-T3 PF10243.4 EPE35991.1 - 0.48 8.8 41.9 0.0039 15.7 21.6 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 AT_hook PF02178.14 EPE35991.1 - 2.6 8.0 11.4 0.22 11.3 3.7 2.6 2 0 0 2 2 2 0 AT hook motif Amidohydro_4 PF13147.1 EPE35992.1 - 1.5e-19 71.1 0.1 3.1e-19 70.0 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EPE35992.1 - 1.6e-19 70.7 0.3 1.1e-10 41.7 0.1 3.1 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_5 PF13594.1 EPE35992.1 - 9.2e-09 34.9 0.2 1.9e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPE35992.1 - 1.8e-07 30.7 0.0 0.00094 18.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Stimulus_sens_1 PF13756.1 EPE35992.1 - 0.037 14.3 0.0 15 6.0 0.0 2.5 2 0 0 2 2 2 0 Stimulus-sensing domain PHD PF00628.24 EPE35993.1 - 5.3e-07 29.2 6.4 1.1e-06 28.2 4.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EPE35993.1 - 1.5e-05 24.1 1.7 3.2e-05 23.1 1.2 1.6 1 0 0 1 1 1 1 PHD-finger CENP-F_leu_zip PF10473.4 EPE35993.1 - 0.0033 17.2 17.0 0.027 14.3 11.6 2.0 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 C1_1 PF00130.17 EPE35993.1 - 0.0045 16.6 2.9 0.0045 16.6 2.0 2.0 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HOOK PF05622.7 EPE35993.1 - 0.013 13.3 6.4 0.019 12.7 4.4 1.2 1 0 0 1 1 1 0 HOOK protein zf-HC5HC2H PF13771.1 EPE35993.1 - 0.028 14.5 0.6 0.068 13.3 0.4 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-PHD-like PF15446.1 EPE35993.1 - 0.028 13.7 0.6 0.075 12.3 0.4 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain TPD52 PF04201.10 EPE35993.1 - 0.046 13.4 7.7 0.1 12.3 4.9 1.9 1 1 1 2 2 2 0 Tumour protein D52 family IncA PF04156.9 EPE35993.1 - 0.049 13.2 5.0 0.07 12.7 3.4 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EPE35993.1 - 0.052 12.5 8.0 0.073 12.1 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EPE35993.1 - 0.11 11.9 7.9 0.45 10.0 1.8 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF904 PF06005.7 EPE35993.1 - 1.2 9.4 12.3 69 3.8 8.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF641 PF04859.7 EPE35993.1 - 1.6 8.4 4.6 15 5.3 3.2 2.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 EPE35993.1 - 1.9 8.3 14.6 9.3 6.1 0.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 EPE35993.1 - 2.6 7.5 7.8 52 3.3 6.3 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 EPE35993.1 - 3.2 7.5 5.2 3 7.6 2.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.3 EPE35993.1 - 3.3 7.5 10.6 5.2 6.9 6.9 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mucin PF01456.12 EPE35994.1 - 0.28 10.9 7.1 0.45 10.2 4.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Cornifin PF02389.10 EPE35995.1 - 0.0017 18.1 7.2 0.0038 17.0 5.0 1.5 1 0 0 1 1 1 1 Cornifin (SPRR) family BLOC1_2 PF10046.4 EPE35995.1 - 0.028 14.5 1.5 0.17 12.0 0.1 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 EPE35995.1 - 0.049 13.5 2.8 0.22 11.4 0.1 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 EPE35995.1 - 0.32 10.7 7.0 0.93 9.2 0.8 2.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein THOC7 PF05615.8 EPE35995.1 - 2.3 8.5 8.6 0.49 10.6 1.4 2.6 3 0 0 3 3 3 0 Tho complex subunit 7 PIP5K PF01504.13 EPE35996.1 - 1.2e-83 280.1 0.1 1.9e-83 279.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase WSC PF01822.14 EPE35997.1 - 5.7e-39 131.9 26.5 1.6e-20 72.7 5.4 2.1 2 0 0 2 2 2 2 WSC domain NAD_binding_6 PF08030.7 EPE35998.1 - 5.7e-32 110.7 0.0 1.5e-31 109.4 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EPE35998.1 - 1.2e-19 70.1 0.0 3.3e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EPE35998.1 - 6.1e-18 65.1 7.8 6.1e-18 65.1 5.4 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EPE35998.1 - 0.0066 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain UQ_con PF00179.21 EPE36000.1 - 1.7e-50 170.0 0.0 2.7e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Acyl-CoA_dh_N PF02771.11 EPE36000.1 - 6.3e-23 81.5 0.2 6.8e-22 78.1 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EPE36000.1 - 7.1e-21 74.8 0.0 1.2e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPE36000.1 - 2.2e-15 55.8 0.0 4.2e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EPE36000.1 - 6.4e-05 23.2 0.1 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Prok-E2_B PF14461.1 EPE36000.1 - 0.0007 19.3 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPE36000.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain XPG_I PF00867.13 EPE36001.1 - 9.2e-30 102.5 0.5 2e-29 101.4 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EPE36001.1 - 7.1e-15 55.1 1.6 1e-14 54.5 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EPE36001.1 - 1.4e-05 25.2 0.1 0.00014 22.0 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.6 EPE36001.1 - 0.026 13.4 4.0 0.039 12.8 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Monellin PF09200.5 EPE36001.1 - 0.029 14.0 0.5 0.082 12.5 0.1 2.0 2 0 0 2 2 2 0 Monellin Fe_dep_repr_C PF02742.10 EPE36001.1 - 0.076 12.7 0.0 12 5.7 0.0 2.8 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain TniB PF05621.6 EPE36001.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MM_CoA_mutase PF01642.17 EPE36001.1 - 0.14 10.2 1.0 0.25 9.4 0.7 1.3 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase XPG_I_2 PF12813.2 EPE36001.1 - 0.2 11.1 1.1 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 XPG domain containing DUF1090 PF06476.7 EPE36001.1 - 0.46 10.1 12.3 0.88 9.2 4.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) PBP_sp32 PF07222.7 EPE36001.1 - 2.1 7.4 5.9 4 6.5 4.1 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RCC1 PF00415.13 EPE36002.1 - 4.6e-32 109.9 1.9 6.3e-05 23.0 0.0 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPE36002.1 - 2.3e-10 39.8 24.4 9.5e-08 31.4 0.0 6.6 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Sec34 PF04136.10 EPE36003.1 - 4.4e-30 104.4 0.2 1.4e-29 102.8 0.1 1.8 1 0 0 1 1 1 1 Sec34-like family Abhydrolase_6 PF12697.2 EPE36004.1 - 8.4e-16 58.5 0.0 3.1e-15 56.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE36004.1 - 8.5e-05 22.2 0.0 0.001 18.7 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPE36004.1 - 0.00031 20.4 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPE36004.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Bromodomain PF00439.20 EPE36006.1 - 1.8e-37 127.1 10.0 4.4e-19 68.1 2.5 2.9 2 1 1 3 3 3 2 Bromodomain BAH PF01426.13 EPE36006.1 - 1.6e-16 60.1 0.7 3.7e-16 58.9 0.5 1.7 1 0 0 1 1 1 1 BAH domain OTU PF02338.14 EPE36007.1 - 7.9e-11 42.5 0.0 1.6e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EPE36007.1 - 0.086 12.1 0.0 0.67 9.2 0.0 2.0 2 0 0 2 2 2 0 Peptidase C65 Otubain PB1 PF00564.19 EPE36007.1 - 0.1 12.2 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 PB1 domain Glyco_hydro_17 PF00332.13 EPE36008.1 - 6.9e-10 38.4 1.5 1.7e-08 33.8 0.3 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 DUF2360 PF10152.4 EPE36008.1 - 0.75 10.0 9.2 0.45 10.7 4.4 2.0 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Ribosomal_S26e PF01283.14 EPE36009.1 - 1.3e-47 160.6 4.8 2.1e-47 160.0 3.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 EPE36009.1 - 0.076 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) ubiquitin PF00240.18 EPE36010.1 - 5.6e-33 112.1 0.5 9.5e-33 111.4 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EPE36010.1 - 8.1e-28 95.9 2.1 1.8e-27 94.8 1.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EPE36010.1 - 5.4e-18 64.4 0.3 9.5e-18 63.6 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPE36010.1 - 3.6e-05 23.9 0.1 0.00017 21.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EPE36010.1 - 0.00075 19.3 0.4 0.0015 18.3 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 EPE36010.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.3 1 1 0 1 1 1 1 Telomere stability and silencing IBR PF01485.16 EPE36010.1 - 0.021 14.7 0.4 0.037 13.9 0.3 1.5 1 0 0 1 1 1 0 IBR domain DUF2407 PF10302.4 EPE36010.1 - 0.025 14.7 0.3 0.035 14.3 0.2 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EPE36010.1 - 0.05 13.6 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) DnaJ PF00226.26 EPE36012.1 - 1.4e-09 37.5 0.1 6.2e-09 35.4 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain Glyco_hydro_18 PF00704.23 EPE36013.1 - 3.5e-100 335.8 6.2 4e-100 335.6 4.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ELYS PF13934.1 EPE36014.1 - 1.5e-60 204.8 0.2 1.7e-60 204.5 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 EPE36015.1 - 1e-78 263.6 0.1 5.2e-78 261.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPE36015.1 - 2.2e-26 92.1 0.0 8.8e-26 90.2 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPE36015.1 - 2.7e-11 43.9 9.4 4.7e-05 23.5 0.1 3.7 3 1 0 3 3 3 2 AAA domain IncA PF04156.9 EPE36015.1 - 5.3e-05 22.8 11.2 5.3e-05 22.8 7.8 7.6 2 2 4 7 7 7 2 IncA protein Filament PF00038.16 EPE36015.1 - 6.7e-05 22.5 40.8 6.7e-05 22.5 28.3 4.9 2 2 0 4 4 4 1 Intermediate filament protein AAA_29 PF13555.1 EPE36015.1 - 0.00021 20.7 0.0 0.00044 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EPE36015.1 - 0.00042 19.5 2.9 0.00042 19.5 2.0 5.6 2 2 5 7 7 7 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 EPE36015.1 - 0.00044 18.8 22.1 0.00044 18.8 15.3 5.4 3 2 2 5 5 5 2 AAA domain GAS PF13851.1 EPE36015.1 - 0.0014 17.8 8.4 0.0014 17.8 5.8 7.6 2 2 4 7 7 7 3 Growth-arrest specific micro-tubule binding SKG6 PF08693.5 EPE36016.1 - 5.9e-09 35.0 0.0 1.2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EPE36016.1 - 0.036 13.5 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2453 PF10507.4 EPE36016.1 - 0.036 13.8 0.1 0.072 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) DUF456 PF04306.8 EPE36016.1 - 0.046 13.7 2.2 0.064 13.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Shisa PF13908.1 EPE36016.1 - 0.59 10.2 8.8 6.5 6.8 6.1 2.2 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4034 PF13226.1 EPE36017.1 - 0.082 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) CCDC-167 PF15188.1 EPE36018.1 - 5.3 7.0 10.7 2.1 8.3 0.3 3.4 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 Linker_histone PF00538.14 EPE36019.1 - 2.1e-24 85.4 0.6 2.1e-24 85.4 0.4 1.7 2 0 0 2 2 2 1 linker histone H1 and H5 family MCPVI PF02993.9 EPE36019.1 - 9.3 6.3 17.6 15 5.6 12.2 1.5 1 0 0 1 1 1 0 Minor capsid protein VI Ribosomal_L27e PF01777.13 EPE36020.1 - 2.9e-36 123.4 2.3 4.2e-36 122.9 1.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EPE36020.1 - 0.0033 17.0 0.6 0.011 15.4 0.4 1.9 1 0 0 1 1 1 1 KOW motif TPT PF03151.11 EPE36021.1 - 3.6e-28 98.1 12.7 3.6e-28 98.1 8.8 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EPE36021.1 - 1.4e-06 27.4 20.1 0.0012 17.8 5.2 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EPE36021.1 - 0.0002 21.4 31.7 0.0014 18.6 8.0 2.8 3 0 0 3 3 3 2 EamA-like transporter family Ish1 PF10281.4 EPE36022.1 - 0.013 15.5 0.3 2.5e+02 1.8 0.0 6.7 7 1 1 8 8 8 0 Putative stress-responsive nuclear envelope protein FtsA PF14450.1 EPE36022.1 - 0.02 14.7 0.5 11 5.9 0.2 4.0 3 1 0 3 3 3 0 Cell division protein FtsA IGR PF09597.5 EPE36023.1 - 6.7e-23 80.3 0.1 1.1e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 IGR protein motif NTR2 PF15458.1 EPE36025.1 - 1.8e-71 240.3 18.7 1.8e-71 240.3 12.9 1.7 2 0 0 2 2 2 1 Nineteen complex-related protein 2 Toxin_43 PF15604.1 EPE36025.1 - 0.017 15.2 1.4 0.017 15.2 1.0 2.2 2 0 0 2 2 2 0 Putative toxin 43 IncA PF04156.9 EPE36025.1 - 0.092 12.3 2.6 0.22 11.0 1.8 1.7 1 0 0 1 1 1 0 IncA protein LSM PF01423.17 EPE36026.1 - 2.8e-19 68.4 0.6 3.3e-19 68.1 0.4 1.1 1 0 0 1 1 1 1 LSM domain Rhodanese PF00581.15 EPE36027.1 - 1.3e-07 31.9 0.0 2.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Cytochrome_CBB3 PF13442.1 EPE36027.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Methyltransf_31 PF13847.1 EPE36029.1 - 1.6e-18 66.7 0.0 2.2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE36029.1 - 9.4e-15 54.8 0.0 1.6e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE36029.1 - 5.8e-12 46.1 0.0 9.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE36029.1 - 8e-11 42.3 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE36029.1 - 1e-10 41.5 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE36029.1 - 3.5e-09 36.2 0.0 5.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EPE36029.1 - 8.2e-09 35.5 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE36029.1 - 3e-07 30.7 0.0 4.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPE36029.1 - 9e-07 28.2 0.1 1.8e-06 27.2 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EPE36029.1 - 9e-07 28.6 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 EPE36029.1 - 3.5e-06 26.7 0.0 6.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 EPE36029.1 - 5.1e-06 25.8 0.0 8.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EPE36029.1 - 1.2e-05 24.5 0.0 1.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EPE36029.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EPE36029.1 - 0.0032 16.5 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase GCD14 PF08704.5 EPE36029.1 - 0.0033 16.9 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_15 PF09445.5 EPE36029.1 - 0.056 13.0 0.5 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase MetW PF07021.7 EPE36029.1 - 0.13 11.6 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Met_10 PF02475.11 EPE36029.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein RrnaAD PF00398.15 EPE36029.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Amidase PF01425.16 EPE36030.1 - 1.6e-91 307.4 0.0 1.9e-91 307.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Lactamase_B PF00753.22 EPE36031.1 - 7.1e-05 22.5 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPE36031.1 - 0.027 14.0 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Zn_clus PF00172.13 EPE36032.1 - 2.7e-07 30.3 8.4 5.4e-07 29.4 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPE36032.1 - 2.1e-06 26.7 0.0 3.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF59 PF01883.14 EPE36033.1 - 4.7e-05 23.2 0.2 0.00026 20.9 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function DUF59 DUF2570 PF10828.3 EPE36033.1 - 0.052 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) GTP_EFTU PF00009.22 EPE36034.1 - 3e-45 153.9 0.0 4.4e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPE36034.1 - 9.4e-25 86.5 0.0 3.8e-24 84.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EPE36034.1 - 1.7e-17 63.0 0.0 5.7e-17 61.3 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPE36034.1 - 1.3e-08 34.8 0.0 3.8e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EPE36034.1 - 5.5e-07 29.3 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EPE36034.1 - 6.7e-06 26.0 0.2 1.2e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPE36034.1 - 0.045 14.2 0.1 0.15 12.5 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 EPE36034.1 - 0.12 11.5 0.2 1.6 7.9 0.1 2.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Thiolase_N PF00108.18 EPE36035.1 - 4.2e-100 334.0 1.5 8.5e-100 333.0 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPE36035.1 - 2.5e-45 152.8 1.0 2.5e-45 152.8 0.7 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EPE36035.1 - 2.4e-05 23.9 0.3 5.9e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EPE36035.1 - 0.035 13.7 1.7 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GNAT_acetyltr_2 PF13718.1 EPE36036.1 - 4.2e-81 270.9 0.0 7.7e-81 270.1 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EPE36036.1 - 3.9e-65 218.7 0.0 1.3e-64 217.1 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EPE36036.1 - 3.9e-40 135.4 0.0 9.8e-40 134.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EPE36036.1 - 1.1e-31 108.9 1.9 3.4e-31 107.3 1.3 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EPE36036.1 - 0.018 15.1 0.0 0.073 13.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4559 PF15112.1 EPE36036.1 - 0.24 10.5 4.6 0.093 11.8 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Amidoligase_2 PF12224.3 EPE36037.1 - 5.1e-30 104.9 0.3 9.1e-30 104.0 0.0 1.6 2 0 0 2 2 2 1 Putative amidoligase enzyme HATPase_c PF02518.21 EPE36038.1 - 2.3e-30 104.5 0.1 5.5e-30 103.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPE36038.1 - 3.2e-22 78.6 0.1 8.2e-22 77.3 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EPE36038.1 - 1.1e-21 76.6 0.1 2.9e-21 75.2 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EPE36038.1 - 3.8e-15 55.7 1.5 2.6e-14 53.0 0.5 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EPE36038.1 - 1.9e-14 53.8 0.0 1.7e-09 37.9 0.0 4.5 4 0 0 4 4 4 1 PAS domain PAS_4 PF08448.5 EPE36038.1 - 3.1e-08 33.6 0.3 7.6e-06 25.9 0.0 3.7 4 0 0 4 4 4 1 PAS fold PAS PF00989.19 EPE36038.1 - 3e-05 23.7 0.0 0.072 12.8 0.0 4.2 4 0 0 4 4 4 1 PAS fold PAS_8 PF13188.1 EPE36038.1 - 0.00032 20.4 0.0 0.051 13.4 0.0 3.5 3 0 0 3 3 3 1 PAS domain DUF807 PF05660.6 EPE36038.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) LNS2 PF08235.8 EPE36039.1 - 4.6e-68 227.7 0.0 7.1e-68 227.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EPE36039.1 - 8.9e-40 134.7 0.0 1.9e-39 133.7 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 EPE36039.1 - 0.00052 19.8 2.3 0.00052 19.8 1.6 2.2 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator Acid_phosphat_B PF03767.9 EPE36039.1 - 0.1 11.9 0.2 0.5 9.6 0.0 2.1 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) SNARE_assoc PF09335.6 EPE36040.1 - 1.3e-14 54.4 4.3 1.3e-14 54.4 3.0 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein WTF PF03303.8 EPE36040.1 - 0.033 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 WTF protein DUF21 PF01595.15 EPE36040.1 - 1 8.6 6.1 0.24 10.6 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 F-box-like PF12937.2 EPE36042.1 - 0.038 13.7 0.1 0.082 12.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like zf-C3HC4 PF00097.20 EPE36043.1 - 2.2e-06 27.1 11.0 4.1e-06 26.3 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE36043.1 - 5.5e-06 25.9 6.9 9e-06 25.2 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE36043.1 - 1e-05 25.2 9.5 1.8e-05 24.4 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPE36043.1 - 1.1e-05 25.0 9.1 1.9e-05 24.2 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPE36043.1 - 1.6e-05 24.7 10.5 2.9e-05 23.9 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPE36043.1 - 0.0082 15.8 5.8 0.02 14.5 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EPE36043.1 - 0.042 13.4 6.3 0.19 11.3 4.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_3 PF14369.1 EPE36043.1 - 0.047 13.6 5.8 0.51 10.3 0.4 2.5 2 0 0 2 2 2 0 zinc-finger zf-Apc11 PF12861.2 EPE36043.1 - 0.047 13.5 3.3 0.092 12.5 2.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EPE36043.1 - 0.051 13.4 10.9 0.13 12.1 7.3 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-CHY PF05495.7 EPE36043.1 - 0.66 10.1 4.6 1.2 9.3 3.2 1.4 1 0 0 1 1 1 0 CHY zinc finger SLT PF01464.15 EPE36045.1 - 0.037 13.5 0.0 0.082 12.4 0.0 1.7 1 1 0 1 1 1 0 Transglycosylase SLT domain Ctr PF04145.10 EPE36046.1 - 2.2e-18 66.6 0.5 2.7e-18 66.4 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Abhydrolase_6 PF12697.2 EPE36047.1 - 2.3e-26 93.1 0.1 2.6e-26 92.9 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE36047.1 - 6.9e-09 35.6 0.0 9.9e-09 35.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF829 PF05705.9 EPE36047.1 - 0.0032 17.1 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Fungal_trans_2 PF11951.3 EPE36048.1 - 3.4e-08 32.4 0.0 4.5e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE36048.1 - 0.00061 19.6 9.4 0.00061 19.6 6.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S9 PF00326.16 EPE36049.1 - 1.5e-54 184.4 0.1 3e-54 183.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE36049.1 - 5.6e-09 35.9 0.0 1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE36049.1 - 5.5e-07 29.6 0.1 1.8e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 EPE36049.1 - 0.00038 20.0 0.0 0.028 14.0 0.0 3.3 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat AXE1 PF05448.7 EPE36049.1 - 0.095 11.1 0.5 1.9 6.8 0.3 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) T2SS-T3SS_pil_N PF13629.1 EPE36049.1 - 0.1 12.1 0.6 2.8 7.5 0.0 3.1 2 2 0 3 3 3 0 Pilus formation protein N terminal region Pkinase PF00069.20 EPE36050.1 - 3.5e-37 127.9 0.0 2.8e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE36050.1 - 1.9e-14 53.3 0.0 1.3e-13 50.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPE36050.1 - 5.8e-05 22.9 0.0 0.00013 21.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPE36050.1 - 0.18 10.6 0.0 1 8.2 0.0 1.9 2 0 0 2 2 2 0 Kinase-like MNE1 PF13762.1 EPE36051.1 - 0.01 15.9 0.3 0.75 9.8 0.0 2.4 2 1 0 2 2 2 1 Mitochondrial splicing apparatus component Jnk-SapK_ap_N PF09744.4 EPE36051.1 - 0.32 10.9 12.6 0.11 12.4 6.8 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 VitD-bind_III PF09164.5 EPE36051.1 - 0.34 10.5 2.1 0.55 9.8 0.2 2.2 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Phage_GPO PF05929.6 EPE36051.1 - 0.37 10.0 4.2 0.81 8.8 2.9 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF342 PF03961.8 EPE36051.1 - 5 5.4 8.4 4.2 5.6 4.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DEAD PF00270.24 EPE36052.1 - 4.2e-45 153.2 1.2 7.8e-45 152.3 0.9 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE36052.1 - 1.2e-27 95.5 0.2 6.1e-27 93.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE36052.1 - 0.0015 18.3 0.0 0.0034 17.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EPE36052.1 - 0.0037 16.8 0.2 0.012 15.1 0.1 1.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPE36052.1 - 0.0097 16.0 0.0 0.027 14.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 EPE36052.1 - 0.014 14.4 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EPE36052.1 - 0.016 14.9 0.1 0.048 13.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain CobA_CobO_BtuR PF02572.10 EPE36052.1 - 0.081 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Flavi_DEAD PF07652.9 EPE36052.1 - 0.095 12.4 0.1 0.49 10.1 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Fanconi_A PF03511.9 EPE36052.1 - 0.098 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein Cupin_8 PF13621.1 EPE36053.1 - 2.6e-16 59.8 0.1 8.1e-15 54.9 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EPE36053.1 - 1.9e-09 37.7 0.2 2.3e-08 34.2 0.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 EPE36053.1 - 0.00026 20.6 0.1 0.00062 19.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE36053.1 - 0.0018 17.8 0.0 0.0047 16.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain NuA4 PF09340.5 EPE36054.1 - 2.7e-19 68.5 0.0 5.1e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 CENP-Q PF13094.1 EPE36054.1 - 0.04 13.9 0.2 0.061 13.3 0.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit PWI PF01480.12 EPE36055.1 - 1.7e-30 104.9 0.3 2.9e-30 104.2 0.2 1.4 1 0 0 1 1 1 1 PWI domain Phage_AlpA PF05930.7 EPE36055.1 - 0.082 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) DUF566 PF04484.7 EPE36055.1 - 1.9 7.9 7.6 2.7 7.4 4.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF566) FAA_hydrolase PF01557.13 EPE36058.1 - 9.7e-51 172.2 0.0 1.2e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.7 EPE36059.1 - 1.5e-59 199.7 0.0 1.7e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EPE36059.1 - 3.3e-05 23.3 0.0 5.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain zf-ribbon_3 PF13248.1 EPE36059.1 - 0.0021 17.1 1.2 0.83 8.9 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.2 EPE36059.1 - 0.0022 17.7 2.5 0.0046 16.7 1.8 1.5 1 0 0 1 1 1 1 Double zinc ribbon AraC_binding PF02311.14 EPE36059.1 - 0.0032 17.1 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EPE36059.1 - 0.0063 15.9 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Cupin Nudix_N_2 PF14803.1 EPE36059.1 - 0.0084 15.7 1.1 2.6 7.7 0.0 2.4 2 0 0 2 2 2 2 Nudix N-terminal TF_Zn_Ribbon PF08271.7 EPE36059.1 - 0.0086 15.3 0.4 0.54 9.6 0.0 2.7 2 0 0 2 2 2 1 TFIIB zinc-binding Cupin_4 PF08007.7 EPE36059.1 - 0.038 13.2 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein FYVE PF01363.16 EPE36059.1 - 0.079 12.8 1.6 0.14 12.0 1.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger ARD PF03079.9 EPE36059.1 - 0.096 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family ADK_lid PF05191.9 EPE36059.1 - 0.12 12.0 2.3 6.9 6.4 0.1 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid Ribosomal_S27 PF01599.14 EPE36059.1 - 0.13 12.1 1.1 9.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S27a OrfB_Zn_ribbon PF07282.6 EPE36059.1 - 1.4 8.6 6.3 16 5.2 0.2 3.0 2 1 2 4 4 4 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.1 EPE36059.1 - 5.6 6.5 7.0 1.2e+02 2.3 4.8 2.6 1 1 0 1 1 1 0 zinc-ribbon domain MGC-24 PF05283.6 EPE36060.1 - 3 7.5 6.2 0.64 9.7 1.3 2.0 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Glyco_hydro_71 PF03659.9 EPE36061.1 - 3.3e-128 427.4 1.1 4e-128 427.1 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Gag_p10 PF02337.12 EPE36061.1 - 0.18 11.5 1.4 0.48 10.2 0.6 2.0 2 0 0 2 2 2 0 Retroviral GAG p10 protein Glyco_hydro_38 PF01074.17 EPE36062.1 - 1.5e-90 303.1 0.8 1.5e-90 303.1 0.6 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EPE36062.1 - 1.7e-75 254.6 0.0 2.8e-75 253.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EPE36062.1 - 3e-27 94.6 0.0 7.2e-27 93.4 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Pro_CA PF00484.14 EPE36063.1 - 1.6e-27 96.3 0.0 1.9e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase NUDIX PF00293.23 EPE36064.1 - 2.7e-16 59.4 0.0 4.8e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SelB-wing_3 PF09107.6 EPE36064.1 - 0.11 11.9 0.1 0.24 10.8 0.1 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix CMD PF02627.15 EPE36065.1 - 8.5e-19 67.1 0.6 1.4e-18 66.4 0.1 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family peroxidase PF00141.18 EPE36066.1 - 3.2e-48 164.2 0.0 4.8e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ApoL PF05461.6 EPE36066.1 - 0.062 12.5 0.8 0.089 12.0 0.5 1.2 1 0 0 1 1 1 0 Apolipoprotein L HEAT_2 PF13646.1 EPE36067.1 - 0.014 15.7 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats Nop14 PF04147.7 EPE36068.1 - 1.9e-253 843.2 28.2 2.4e-253 842.9 19.6 1.0 1 0 0 1 1 1 1 Nop14-like family Ribosomal_L36e PF01158.13 EPE36069.1 - 2.2e-38 130.1 8.2 2.5e-38 130.0 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EPE36069.1 - 0.025 13.6 0.2 0.028 13.5 0.1 1.1 1 0 0 1 1 1 0 LemA family MRP-L28 PF09812.4 EPE36069.1 - 0.071 12.9 1.3 0.077 12.8 0.9 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Transcrip_act PF04949.8 EPE36069.1 - 0.23 11.0 2.8 0.28 10.8 1.9 1.2 1 0 0 1 1 1 0 Transcriptional activator TUG-UBL1 PF11470.3 EPE36070.1 - 2.8e-24 84.8 0.0 7.4e-24 83.4 0.0 1.7 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EPE36070.1 - 2.6e-07 30.5 0.0 1.2e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 UBX domain FadA PF09403.5 EPE36070.1 - 7.3 6.6 12.2 14 5.7 0.6 2.4 2 0 0 2 2 2 0 Adhesion protein FadA Proteasome PF00227.21 EPE36071.1 - 3.9e-40 137.1 0.0 4.7e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit E1-E2_ATPase PF00122.15 EPE36072.1 - 6.8e-64 215.0 8.2 6.4e-63 211.8 4.8 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPE36072.1 - 7.1e-45 152.7 6.0 1.5e-44 151.7 4.1 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPE36072.1 - 9.7e-34 117.6 0.0 1.8e-32 113.5 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPE36072.1 - 7.7e-22 77.0 0.0 1.5e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EPE36072.1 - 3.1e-19 68.1 0.0 8e-19 66.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EPE36072.1 - 3.5e-17 63.2 0.0 9.9e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPE36072.1 - 1.6e-07 31.2 4.7 5e-06 26.2 1.3 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPE36072.1 - 0.03 14.5 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3431 PF11913.3 EPE36073.1 - 6.4e-83 277.6 0.6 8.3e-83 277.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) PAS_9 PF13426.1 EPE36074.1 - 1.3e-18 67.3 0.0 2e-15 57.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EPE36074.1 - 0.00096 18.9 0.0 0.025 14.3 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EPE36074.1 - 0.014 15.4 0.0 0.34 10.9 0.0 2.5 2 0 0 2 2 2 0 PAS fold BAR PF03114.13 EPE36075.1 - 3.6e-52 177.1 7.3 4.8e-52 176.7 5.1 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EPE36075.1 - 3.8e-06 26.0 4.1 7.1e-06 25.1 2.9 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Amidohydro_1 PF01979.15 EPE36075.1 - 0.16 11.5 0.0 0.26 10.9 0.0 1.3 1 1 0 1 1 1 0 Amidohydrolase family Arfaptin PF06456.8 EPE36075.1 - 0.65 9.3 8.1 1.5 8.1 5.6 1.7 1 1 0 1 1 1 0 Arfaptin-like domain APG6 PF04111.7 EPE36075.1 - 1.6 7.7 9.5 0.36 9.8 4.2 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 zf-RING_2 PF13639.1 EPE36076.1 - 1.2e-10 41.0 8.7 2.5e-10 40.0 6.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE36076.1 - 4.4e-10 39.4 10.6 9.3e-10 38.3 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE36076.1 - 3e-09 36.4 6.9 5.1e-09 35.6 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE36076.1 - 1.2e-08 34.4 9.4 3e-08 33.1 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE36076.1 - 2.9e-07 30.1 7.6 5.4e-07 29.2 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPE36076.1 - 4.1e-07 29.6 7.2 9.8e-07 28.3 1.6 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EPE36076.1 - 1.1e-06 28.3 10.7 2.3e-06 27.3 7.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EPE36076.1 - 1.4e-06 28.3 4.7 3.6e-06 27.0 3.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPE36076.1 - 3.4e-05 23.5 2.3 7e-05 22.5 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EPE36076.1 - 0.0026 17.5 5.2 0.0068 16.1 2.3 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EPE36076.1 - 0.0036 16.8 3.5 0.0036 16.8 2.4 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 EPE36076.1 - 0.017 14.6 7.4 0.039 13.4 5.2 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Siva PF05458.7 EPE36076.1 - 0.039 13.5 1.4 0.088 12.3 1.0 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_4 PF14570.1 EPE36076.1 - 0.041 13.4 7.2 0.075 12.6 5.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Vps39_2 PF10367.4 EPE36076.1 - 0.063 13.4 0.9 0.15 12.2 0.7 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-Nse PF11789.3 EPE36076.1 - 1.8 8.1 7.2 3.8 7.0 4.4 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 EPE36076.1 - 2.6 7.5 11.4 0.29 10.6 4.4 2.0 2 1 1 3 3 3 0 P-11 zinc finger IBR PF01485.16 EPE36076.1 - 5.7 6.8 8.0 12 5.9 4.2 2.3 1 1 1 2 2 2 0 IBR domain Git3 PF11710.3 EPE36077.1 - 8.4e-23 80.9 11.7 1.4e-22 80.2 8.1 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EPE36077.1 - 0.058 13.1 0.2 0.058 13.1 0.1 2.5 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term ABC_tran PF00005.22 EPE36078.1 - 6.2e-48 162.5 0.0 5.4e-23 81.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPE36078.1 - 1.2e-20 74.6 0.1 0.00053 20.0 0.0 4.3 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EPE36078.1 - 9.1e-20 70.2 5.5 9.1e-20 70.2 3.8 2.1 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 EPE36078.1 - 2.7e-10 39.8 0.2 0.0023 17.1 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPE36078.1 - 5.9e-09 36.5 2.1 0.036 14.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EPE36078.1 - 7.4e-09 35.0 0.6 0.0011 18.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPE36078.1 - 4.5e-07 29.1 0.1 0.0014 17.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EPE36078.1 - 1.4e-06 29.1 0.1 0.034 14.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EPE36078.1 - 1.8e-06 28.2 0.2 0.028 14.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EPE36078.1 - 1e-05 25.7 0.0 0.13 12.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EPE36078.1 - 3.5e-05 23.7 0.0 0.088 12.7 0.0 3.0 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EPE36078.1 - 5e-05 23.3 0.1 0.17 11.8 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EPE36078.1 - 8.5e-05 23.0 0.0 0.36 11.3 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 EPE36078.1 - 0.00012 21.8 0.1 0.56 9.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.17 EPE36078.1 - 0.00012 22.1 1.2 1.1 9.4 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_15 PF13175.1 EPE36078.1 - 0.00015 20.9 0.0 0.052 12.5 0.0 2.8 3 1 0 3 3 2 1 AAA ATPase domain AAA PF00004.24 EPE36078.1 - 0.00039 20.6 0.0 0.7 10.0 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EPE36078.1 - 0.00041 20.3 0.0 0.27 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPE36078.1 - 0.00066 19.4 0.1 0.93 9.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EPE36078.1 - 0.00074 19.2 1.0 0.89 9.2 0.0 3.1 2 1 0 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 EPE36078.1 - 0.0013 17.6 0.0 0.92 8.3 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain AAA_14 PF13173.1 EPE36078.1 - 0.0014 18.5 0.0 1.8 8.4 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EPE36078.1 - 0.0015 18.4 0.0 0.18 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPE36078.1 - 0.0024 17.3 0.1 0.46 9.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EPE36078.1 - 0.0041 16.5 0.5 0.98 8.7 0.2 2.5 2 0 0 2 2 2 1 AAA-like domain SbcCD_C PF13558.1 EPE36078.1 - 0.0066 16.3 0.7 0.78 9.6 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EPE36078.1 - 0.013 15.1 0.1 0.3 10.7 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EPE36078.1 - 0.017 14.9 0.1 12 5.7 0.0 3.6 4 0 0 4 4 4 0 Dynamin family DUF2813 PF11398.3 EPE36078.1 - 0.018 14.1 0.6 4.8 6.1 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF2813) ABC_ATPase PF09818.4 EPE36078.1 - 0.019 13.5 1.2 9.9 4.6 0.0 3.4 4 0 0 4 4 4 0 Predicted ATPase of the ABC class DAP3 PF10236.4 EPE36078.1 - 0.025 13.5 0.6 4.3 6.1 0.1 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.4 EPE36078.1 - 0.038 13.4 0.7 3.6 7.0 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 EPE36078.1 - 0.045 13.2 0.0 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 EPE36078.1 - 0.059 12.2 0.1 2.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 EPE36078.1 - 0.092 12.4 0.0 5.8 6.5 0.0 2.6 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.13 EPE36078.1 - 0.11 11.8 0.1 11 5.3 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B SNF2_N PF00176.18 EPE36079.1 - 1.1e-69 234.4 0.9 2e-69 233.7 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EPE36079.1 - 2.9e-50 169.9 19.0 2.9e-50 169.9 13.2 4.3 5 1 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.26 EPE36079.1 - 6.4e-16 57.9 0.0 2.1e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Exo_endo_phos PF03372.18 EPE36080.1 - 2e-17 63.9 0.1 4.4e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Biotin_lipoyl PF00364.17 EPE36081.1 - 1.8e-20 72.3 0.7 4.6e-20 71.0 0.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EPE36081.1 - 8.4e-06 25.3 0.0 5.5e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like E3_binding PF02817.12 EPE36081.1 - 0.00012 21.6 0.3 0.00036 20.0 0.0 2.0 2 0 0 2 2 2 1 e3 binding domain QRPTase_N PF02749.11 EPE36081.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain DNA_ligase_aden PF01653.13 EPE36081.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain DUF4518 PF15008.1 EPE36082.1 - 0.27 10.2 0.8 0.4 9.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) LRR_4 PF12799.2 EPE36083.1 - 2.3e-14 52.6 7.2 0.0001 21.8 3.8 4.2 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE36083.1 - 4.6e-13 48.7 17.0 5.3e-08 32.4 2.2 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EPE36083.1 - 1.3e-08 33.7 7.8 2.1 8.6 0.3 6.3 5 1 1 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 EPE36083.1 - 0.0004 20.1 8.2 3.2 8.1 0.0 5.4 4 1 1 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 EPE36083.1 - 0.0039 17.1 10.4 12 6.6 0.2 5.7 5 0 0 5 5 5 2 Leucine rich repeat Metallophos PF00149.23 EPE36084.1 - 1.4e-44 151.9 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rdx PF10262.4 EPE36085.1 - 5.2e-17 61.6 0.0 9e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.17 EPE36086.1 - 4.7e-25 87.1 0.0 5.9e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF3591 PF12157.3 EPE36087.1 - 1.4e-180 600.6 0.4 1.9e-180 600.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.18 EPE36087.1 - 0.019 14.8 1.1 0.044 13.7 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EPE36087.1 - 0.13 11.9 0.8 0.33 10.6 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle PCI PF01399.22 EPE36088.1 - 1.7e-08 34.6 0.6 6.9e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 PCI domain WSC PF01822.14 EPE36089.1 - 4e-28 97.1 25.8 1.3e-17 63.4 4.0 7.7 5 3 2 7 7 7 2 WSC domain DUF605 PF04652.11 EPE36089.1 - 0.0012 18.2 30.7 0.0012 18.2 21.3 2.1 2 0 0 2 2 2 1 Vta1 like Dioxygenase_C PF00775.16 EPE36090.1 - 7.5e-13 48.1 0.1 1.2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Fork_head PF00250.13 EPE36091.1 - 1.4e-32 111.5 0.1 2.7e-32 110.6 0.1 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EPE36091.1 - 1.3e-08 34.7 0.0 3.9e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 FHA domain Aminotran_3 PF00202.16 EPE36092.1 - 1.8e-80 270.3 0.0 2.2e-80 270.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EPE36092.1 - 0.0068 15.3 0.0 0.16 10.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II CLU PF13236.1 EPE36093.1 - 4.3e-80 268.2 0.0 8.1e-80 267.3 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EPE36093.1 - 2e-47 161.2 0.0 1.1e-46 158.9 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EPE36093.1 - 4.6e-24 84.3 0.1 1.3e-23 82.8 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EPE36093.1 - 7.1e-23 80.3 8.1 4.9e-11 42.4 0.3 3.5 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EPE36093.1 - 1.6e-18 65.9 1.7 2.3e-05 24.1 0.1 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EPE36093.1 - 1.3e-07 31.1 1.3 0.004 16.7 0.0 3.1 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EPE36093.1 - 0.00033 20.3 2.8 0.22 11.5 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE36093.1 - 0.051 13.3 0.1 13 5.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPE36093.1 - 0.058 13.2 3.9 1 9.3 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPE36093.1 - 0.071 12.7 1.3 20 4.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat NAD_binding_6 PF08030.7 EPE36095.1 - 8.1e-20 71.3 0.0 1.7e-11 44.2 0.0 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPE36095.1 - 2e-19 69.8 10.8 2e-19 69.8 7.5 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EPE36095.1 - 3.9e-14 52.3 0.0 1.5e-13 50.4 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain DUF3671 PF12420.3 EPE36095.1 - 0.67 9.9 3.5 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function Peptidase_A4 PF01828.12 EPE36096.1 - 2.5e-38 131.2 0.0 3.1e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family Yippee-Mis18 PF03226.9 EPE36097.1 - 1e-23 83.1 0.9 1.2e-23 83.0 0.6 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 EPE36097.1 - 0.0026 17.7 0.5 0.13 12.2 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease Endonuclease_7 PF02945.10 EPE36097.1 - 0.013 15.2 2.6 0.031 14.0 1.8 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII DUF2039 PF10217.4 EPE36097.1 - 0.015 15.3 1.3 0.052 13.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.3 EPE36097.1 - 0.022 14.6 1.7 0.048 13.5 1.1 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.8 EPE36097.1 - 0.049 13.5 1.8 0.78 9.6 0.2 2.1 1 1 1 2 2 2 0 Erv1 / Alr family zf-CHY PF05495.7 EPE36097.1 - 0.052 13.7 2.0 6.1 7.0 0.0 2.2 2 0 0 2 2 2 0 CHY zinc finger DUF3268 PF11672.3 EPE36097.1 - 0.054 13.5 1.1 0.54 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) GFA PF04828.9 EPE36097.1 - 0.09 12.7 1.5 1 9.3 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Sen15 PF09631.5 EPE36098.1 - 7.2e-25 87.1 0.0 1.3e-24 86.3 0.0 1.4 1 1 0 1 1 1 1 Sen15 protein DUF2985 PF11204.3 EPE36099.1 - 5.5e-39 131.7 1.3 5.5e-39 131.7 0.9 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2985) EamA PF00892.15 EPE36100.1 - 3.4e-09 36.8 27.5 1.9e-05 24.7 2.4 3.6 2 1 1 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.10 EPE36100.1 - 3.9e-09 35.9 3.8 3.9e-09 35.9 2.7 2.3 2 1 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 EPE36100.1 - 6.3e-06 25.9 20.6 0.0057 16.3 6.7 2.9 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EPE36100.1 - 7.5e-06 25.0 7.3 1.1e-05 24.5 4.6 1.6 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.1 EPE36100.1 - 0.0074 16.4 4.7 0.0074 16.4 3.2 3.5 2 1 0 3 3 3 1 Multidrug resistance efflux transporter TrbC PF04956.8 EPE36100.1 - 9.7 6.2 13.1 6.1 6.9 1.1 3.6 4 0 0 4 4 4 0 TrbC/VIRB2 family zf-C2H2_4 PF13894.1 EPE36101.1 - 0.00076 19.6 8.7 1.8 9.0 0.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE36101.1 - 0.0011 19.2 8.5 0.31 11.4 0.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPE36101.1 - 0.33 11.3 8.1 0.65 10.3 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Peptidase_C2 PF00648.16 EPE36102.1 - 3.8e-24 85.2 0.0 5.9e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EPE36102.1 - 4.5e-18 65.2 0.0 2.1e-14 53.4 0.0 3.0 2 1 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.13 EPE36102.1 - 1.3e-06 28.1 2.1 2.1e-06 27.5 1.5 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 EPE36103.1 - 2.6e-53 177.7 1.6 1.5e-18 66.2 0.0 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein SAM_2 PF07647.12 EPE36104.1 - 2e-10 40.3 0.0 3.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EPE36104.1 - 4.1e-06 26.8 0.1 8.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_11 PF13414.1 EPE36105.1 - 3.2e-07 29.8 1.2 0.057 13.0 0.0 3.8 2 1 2 4 4 4 3 TPR repeat TPR_19 PF14559.1 EPE36105.1 - 0.00018 21.7 0.1 2.5 8.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPE36105.1 - 0.0037 16.9 0.8 2 8.4 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPE36105.1 - 0.018 14.6 0.3 11 5.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPE36105.1 - 0.024 14.7 0.1 2.8 8.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPE36105.1 - 0.04 14.5 5.9 55 4.8 0.0 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.3 EPE36105.1 - 0.12 11.0 2.8 0.29 9.8 0.0 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 EPE36105.1 - 0.13 12.1 1.3 5.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPE36105.1 - 0.33 11.6 9.2 5.2 7.8 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPE36106.1 - 3.7e-18 64.9 13.5 4.3e-08 32.6 0.3 4.5 3 1 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 EPE36106.1 - 2.8e-15 55.1 16.4 1.5e-05 24.3 0.3 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EPE36106.1 - 1.8e-13 50.1 16.8 0.00036 20.3 1.9 5.3 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EPE36106.1 - 4.4e-11 41.8 15.5 0.0038 17.0 0.3 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPE36106.1 - 6.7e-10 38.0 8.2 0.0011 18.5 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPE36106.1 - 3.7e-08 32.9 0.8 0.012 15.7 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE36106.1 - 1.3e-07 31.6 6.3 0.16 12.6 0.0 5.9 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE36106.1 - 1.3e-06 28.8 4.9 0.32 11.7 0.2 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPE36106.1 - 2.7e-06 26.7 7.3 0.0033 17.1 0.2 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPE36106.1 - 6.5e-06 26.2 3.6 0.0034 17.7 0.1 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPE36106.1 - 3.1e-05 24.2 13.5 0.072 13.4 0.9 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPE36106.1 - 0.00045 20.0 4.2 0.75 9.8 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EPE36106.1 - 0.021 14.9 13.2 0.068 13.3 0.2 4.3 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EPE36106.1 - 0.58 10.0 3.9 8.5 6.3 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SPRY PF00622.23 EPE36107.1 - 5.6e-23 81.3 0.0 9e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Peptidase_C12 PF01088.16 EPE36108.1 - 4e-71 238.5 0.0 1e-70 237.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Zn_clus PF00172.13 EPE36109.1 - 5.4e-08 32.6 14.5 8.4e-08 31.9 10.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE36109.1 - 1.6e-07 30.3 1.0 2.8e-07 29.4 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT PF02985.17 EPE36110.1 - 7e-30 100.4 6.6 3.5e-05 23.5 0.0 10.0 10 0 0 10 10 9 5 HEAT repeat HEAT_EZ PF13513.1 EPE36110.1 - 2.8e-29 100.8 10.5 5.1e-14 52.2 0.0 10.9 9 3 2 11 11 11 6 HEAT-like repeat HEAT_2 PF13646.1 EPE36110.1 - 6.7e-24 83.9 0.0 1.7e-07 31.4 0.0 7.6 3 3 3 6 6 6 4 HEAT repeats Vac14_Fab1_bd PF12755.2 EPE36110.1 - 4.4e-09 36.6 0.2 0.36 11.2 0.0 6.9 6 1 2 8 8 7 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EPE36110.1 - 1e-05 25.1 2.6 0.2 11.5 0.0 6.3 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 EPE36110.1 - 1.8e-05 23.6 3.5 0.56 8.8 0.0 4.8 5 0 0 5 5 5 3 RNAPII transcription regulator C-terminal IBN_N PF03810.14 EPE36110.1 - 6.7e-05 22.7 0.0 0.0027 17.5 0.0 3.4 2 1 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 EPE36110.1 - 0.00023 19.6 0.0 0.42 8.8 0.0 3.7 3 0 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 EPE36110.1 - 0.00058 19.2 0.1 5.6 6.2 0.0 5.9 7 1 0 8 8 8 1 CLASP N terminal RIX1 PF08167.7 EPE36110.1 - 0.0078 15.9 0.9 13 5.4 0.0 5.0 3 3 1 4 4 4 1 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 EPE36110.1 - 0.025 15.0 1.2 21 5.9 0.0 4.5 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Abhydrolase_1 PF00561.15 EPE36112.1 - 7.1e-12 45.3 0.0 7e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE36112.1 - 1.5e-10 41.3 0.0 3e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE36112.1 - 0.032 13.9 0.0 0.14 11.8 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE36112.1 - 0.065 12.4 0.0 0.28 10.3 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Flavin_Reduct PF01613.13 EPE36113.1 - 6.7e-16 58.5 0.0 9.7e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain adh_short PF00106.20 EPE36114.1 - 3.2e-28 98.7 2.0 4.9e-28 98.1 1.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE36114.1 - 1.4e-22 80.6 0.1 2.3e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE36114.1 - 4.7e-13 49.1 0.7 6.8e-13 48.6 0.5 1.2 1 0 0 1 1 1 1 KR domain N2227 PF07942.7 EPE36115.1 - 4.6e-96 320.9 0.0 5.7e-96 320.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EPE36115.1 - 2.7e-07 30.4 0.0 4.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE36115.1 - 0.00038 20.8 0.1 0.0019 18.6 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE36115.1 - 0.0024 18.3 0.0 0.0053 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE36115.1 - 0.016 15.7 0.0 0.06 13.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EPE36115.1 - 0.027 13.3 0.0 0.058 12.2 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase Methyltransf_31 PF13847.1 EPE36115.1 - 0.044 13.3 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PAP_central PF04928.12 EPE36116.1 - 1e-103 345.6 0.0 1.4e-103 345.1 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EPE36116.1 - 6.1e-44 149.3 0.7 1.4e-43 148.1 0.5 1.6 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EPE36116.1 - 1.1e-07 32.0 0.0 2.8e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2183 PF09949.4 EPE36117.1 - 1.1e-33 115.1 0.0 6.3e-33 112.7 0.0 2.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.1 EPE36117.1 - 0.095 12.7 0.2 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Mid2 PF04478.7 EPE36118.1 - 0.0014 18.0 0.7 0.0025 17.2 0.5 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF1049 PF06305.6 EPE36118.1 - 0.009 15.4 0.2 0.024 14.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) Herpes_gE PF02480.11 EPE36118.1 - 0.011 13.9 0.1 0.011 13.9 0.1 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EPE36118.1 - 0.027 14.8 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 EPE36118.1 - 0.036 12.8 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4381 PF14316.1 EPE36118.1 - 0.097 12.7 0.3 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Zn_clus PF00172.13 EPE36119.1 - 3.8e-07 29.9 8.4 3.8e-07 29.9 5.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE36119.1 - 1.2e-05 24.0 0.1 2.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4045 PF13254.1 EPE36120.1 - 2.6e-104 349.8 44.1 9.6e-65 219.4 19.7 6.0 3 3 2 6 6 6 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EPE36120.1 - 2.5e-12 46.2 0.0 4.6e-05 23.0 0.0 3.6 3 0 0 3 3 3 2 Gelsolin repeat Arf PF00025.16 EPE36121.1 - 7.6e-51 171.8 0.4 8.4e-51 171.6 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EPE36121.1 - 4e-11 42.5 0.0 4.7e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EPE36121.1 - 5.3e-07 28.6 0.0 6.6e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 EPE36121.1 - 1.7e-06 27.3 0.0 2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPE36121.1 - 2e-05 24.1 0.0 2.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EPE36121.1 - 2.2e-05 24.9 0.0 3.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPE36121.1 - 0.0095 15.8 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 EPE36121.1 - 0.017 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.5 EPE36121.1 - 0.018 14.2 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Acetyltransf_1 PF00583.19 EPE36122.1 - 1.3e-05 25.0 0.1 4.4e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE36122.1 - 0.0023 18.0 0.2 0.015 15.4 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPE36122.1 - 0.099 12.5 0.0 0.78 9.6 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.24 EPE36123.1 - 4.2e-43 146.7 0.0 1.1e-42 145.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE36123.1 - 3.5e-25 87.6 0.0 8e-25 86.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EPE36123.1 - 0.00013 20.4 0.6 0.0016 16.9 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF1253) Cutinase PF01083.17 EPE36123.1 - 0.16 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase Cupin_1 PF00190.17 EPE36124.1 - 2.3e-28 98.4 0.0 2e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EPE36124.1 - 1.9e-25 88.1 1.4 3.2e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EPE36124.1 - 1.4e-10 40.9 0.3 5.5e-06 26.1 0.2 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain FdtA PF05523.6 EPE36124.1 - 9e-05 21.9 0.0 0.0022 17.5 0.0 2.1 2 0 0 2 2 2 1 WxcM-like, C-terminal CENP-C_C PF11699.3 EPE36124.1 - 0.00017 21.4 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 2 Mif2/CENP-C like Ectoine_synth PF06339.7 EPE36124.1 - 0.00026 20.9 0.1 0.84 9.5 0.0 2.2 2 0 0 2 2 2 2 Ectoine synthase Cupin_6 PF12852.2 EPE36124.1 - 0.00028 20.5 0.0 0.018 14.6 0.0 2.2 2 0 0 2 2 2 1 Cupin MannoseP_isomer PF01050.13 EPE36124.1 - 0.0011 18.5 0.0 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.7 EPE36124.1 - 0.002 17.4 0.0 0.74 9.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) GPI PF06560.6 EPE36124.1 - 0.011 14.8 0.1 0.031 13.3 0.0 1.7 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Cupin_8 PF13621.1 EPE36124.1 - 0.042 13.3 0.1 0.79 9.1 0.1 2.1 2 0 0 2 2 2 0 Cupin-like domain ARD PF03079.9 EPE36124.1 - 0.068 13.1 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 ARD/ARD' family DUF2347 PF09804.4 EPE36125.1 - 2.7e-104 348.4 0.0 3.9e-104 347.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EPE36125.1 - 4.4e-53 179.9 0.2 6.8e-53 179.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 EPE36125.1 - 0.00054 19.6 0.0 0.0018 17.9 0.0 1.8 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EPE36125.1 - 0.0027 16.2 0.0 0.061 11.7 0.0 2.3 2 1 0 2 2 2 1 Transport protein Avl9 Sec63 PF02889.11 EPE36126.1 - 8.5e-42 143.4 0.0 4.6e-40 137.7 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EPE36126.1 - 6e-17 61.1 0.8 2.4e-16 59.2 0.4 2.1 2 0 0 2 2 2 1 DnaJ domain SNF2_N PF00176.18 EPE36127.1 - 3.4e-66 223.0 0.0 4.6e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPE36127.1 - 2.6e-11 43.1 0.0 5.5e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE36127.1 - 5.5e-07 29.5 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EPE36127.1 - 0.0031 16.3 0.0 0.0061 15.4 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 BP28CT PF08146.7 EPE36128.1 - 8.4e-43 145.7 0.8 8.4e-43 145.7 0.5 2.5 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EPE36128.1 - 3.6e-28 97.9 0.7 3.6e-28 97.9 0.5 5.5 7 0 0 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EPE36128.1 - 9.2e-08 32.2 14.1 0.33 11.2 0.1 7.1 5 2 1 6 6 6 3 HEAT repeats HEAT PF02985.17 EPE36128.1 - 2.3e-06 27.2 8.7 0.02 14.9 0.1 5.5 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EPE36128.1 - 0.16 12.5 12.2 3.1 8.4 0.2 7.0 5 1 1 6 6 6 0 HEAT-like repeat NRDE-2 PF08424.5 EPE36129.1 - 1e-87 294.0 2.3 2.3e-86 289.6 0.3 3.1 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EPE36129.1 - 0.00085 19.7 0.2 6.3 7.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Peptidase_M24 PF00557.19 EPE36130.1 - 1.8e-57 194.2 0.1 2.6e-57 193.7 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EPE36130.1 - 3.9e-18 65.1 0.0 7.7e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain PPR PF01535.15 EPE36130.1 - 0.08 12.9 0.1 0.57 10.2 0.0 2.5 3 0 0 3 3 3 0 PPR repeat RPN7 PF10602.4 EPE36131.1 - 4.1e-52 176.1 0.0 6.3e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EPE36131.1 - 2.9e-10 40.3 0.0 7.8e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 EPE36131.1 - 0.031 14.1 1.1 2.1 8.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DHC_N2 PF08393.8 EPE36131.1 - 0.034 12.6 0.1 0.079 11.4 0.1 1.5 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 Fungal_trans PF04082.13 EPE36132.1 - 1e-21 76.9 0.0 2e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE36132.1 - 1.9e-11 43.6 12.6 3.2e-11 42.9 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EPE36132.1 - 0.061 13.2 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Gal4-like dimerisation domain Sulfotransfer_3 PF13469.1 EPE36133.1 - 0.0019 19.1 0.0 0.0089 16.9 0.0 2.0 2 1 0 2 2 2 1 Sulfotransferase family Mhr1 PF12829.2 EPE36134.1 - 1.2e-27 95.5 0.5 1.2e-27 95.5 0.3 1.9 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination AAA_2 PF07724.9 EPE36135.1 - 6.2e-47 159.6 0.0 4.6e-46 156.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EPE36135.1 - 2.3e-28 99.0 0.0 1.9e-14 54.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EPE36135.1 - 7.4e-23 80.2 0.1 2.5e-22 78.5 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EPE36135.1 - 1.7e-17 64.0 8.3 1.4e-06 28.4 0.0 6.0 4 3 3 7 7 6 2 AAA ATPase domain AAA_5 PF07728.9 EPE36135.1 - 1.9e-15 56.7 0.0 4.3e-10 39.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPE36135.1 - 7.6e-14 51.9 0.0 2.7e-05 24.3 0.0 4.1 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.1 EPE36135.1 - 1.2e-08 35.2 0.3 0.0063 16.8 0.0 3.8 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EPE36135.1 - 1.6e-08 34.1 0.0 1.4e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 EPE36135.1 - 1e-07 32.7 5.5 0.0056 17.4 0.0 3.9 4 1 0 4 4 3 2 AAA domain AAA_19 PF13245.1 EPE36135.1 - 9.6e-07 28.4 2.1 0.035 13.8 0.0 3.5 4 0 0 4 4 2 2 Part of AAA domain IstB_IS21 PF01695.12 EPE36135.1 - 1.2e-06 28.1 0.0 0.026 13.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 EPE36135.1 - 1.3e-06 28.2 5.9 0.0031 17.2 0.1 5.7 4 1 2 6 6 6 1 Archaeal ATPase Mg_chelatase PF01078.16 EPE36135.1 - 3.7e-06 26.2 0.1 0.066 12.3 0.0 3.5 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EPE36135.1 - 1.6e-05 24.7 0.0 0.096 12.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EPE36135.1 - 2e-05 24.6 0.0 0.23 11.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain Clp_N PF02861.15 EPE36135.1 - 2e-05 24.4 0.7 0.032 14.1 0.0 3.7 3 0 0 3 3 2 1 Clp amino terminal domain AAA_3 PF07726.6 EPE36135.1 - 5.6e-05 22.7 0.0 0.88 9.1 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EPE36135.1 - 5.8e-05 22.8 0.0 0.35 10.5 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EPE36135.1 - 7.9e-05 22.7 0.0 0.53 10.4 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ResIII PF04851.10 EPE36135.1 - 8.6e-05 22.4 0.0 0.12 12.1 0.0 3.6 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EPE36135.1 - 0.00023 20.1 0.0 0.031 13.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 EPE36135.1 - 0.00031 21.0 0.0 0.76 10.0 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.7 EPE36135.1 - 0.00039 19.5 0.0 0.082 11.9 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 EPE36135.1 - 0.00054 19.4 0.7 1.5 8.1 0.0 3.6 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 EPE36135.1 - 0.00063 18.9 0.0 0.3 10.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EPE36135.1 - 0.00067 19.1 1.4 0.33 10.3 0.0 4.2 4 1 0 4 4 4 1 AAA-like domain Torsin PF06309.6 EPE36135.1 - 0.00083 19.2 0.0 0.0038 17.0 0.0 2.0 2 0 0 2 2 2 1 Torsin AAA_29 PF13555.1 EPE36135.1 - 0.0013 18.1 0.0 0.71 9.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EPE36135.1 - 0.0021 17.9 0.0 0.045 13.7 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_24 PF13479.1 EPE36135.1 - 0.0022 17.6 0.0 1.6 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EPE36135.1 - 0.0057 16.3 0.0 0.45 10.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 EPE36135.1 - 0.0082 16.1 0.1 3.3 7.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 EPE36135.1 - 0.0086 15.8 0.0 0.24 11.1 0.0 2.6 2 0 0 2 2 2 1 NTPase SRP54 PF00448.17 EPE36135.1 - 0.018 14.4 0.0 2.6 7.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 EPE36135.1 - 0.043 13.3 0.0 8.9 5.7 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 EPE36135.1 - 0.076 12.6 0.0 17 5.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EPE36135.1 - 0.1 12.1 0.0 6 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EPE36135.1 - 1.8 8.8 12.3 0.8 9.9 0.0 3.9 2 1 0 3 3 2 0 AAA domain DUF4140 PF13600.1 EPE36135.1 - 4.1 7.9 12.3 8.8 6.8 0.3 3.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Golgin_A5 PF09787.4 EPE36136.1 - 0.066 11.7 1.1 0.085 11.3 0.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 MMR1 PF08505.5 EPE36136.1 - 0.66 9.9 4.2 0.25 11.3 1.2 1.5 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein ABC_tran PF00005.22 EPE36137.1 - 2.5e-45 154.1 0.0 4.4e-28 98.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EPE36137.1 - 1.8e-34 119.4 25.0 2.8e-16 59.7 7.9 3.9 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 EPE36137.1 - 3.4e-14 52.6 0.0 2e-08 33.7 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPE36137.1 - 3.1e-12 47.0 0.0 0.11 12.4 0.0 4.4 3 1 1 4 4 4 4 AAA domain AAA_22 PF13401.1 EPE36137.1 - 1.8e-06 28.1 0.1 0.0035 17.4 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EPE36137.1 - 1.9e-06 27.4 0.7 0.034 13.5 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EPE36137.1 - 0.00012 22.4 0.6 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPE36137.1 - 0.00028 20.9 3.1 0.053 13.4 0.0 3.5 2 2 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EPE36137.1 - 0.0014 18.4 0.4 0.018 14.7 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 EPE36137.1 - 0.0017 17.5 0.1 0.85 8.7 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 EPE36137.1 - 0.0065 16.6 0.4 2.2 8.4 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EPE36137.1 - 0.0085 15.0 0.9 1.3 7.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 EPE36137.1 - 0.018 14.5 8.0 0.099 12.1 1.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EPE36137.1 - 0.021 14.7 0.0 0.76 9.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 EPE36137.1 - 0.024 15.1 0.0 0.77 10.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 EPE36137.1 - 0.03 13.9 0.3 0.35 10.5 0.0 2.8 2 1 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EPE36137.1 - 0.056 13.2 0.9 1.2 8.9 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain SbcCD_C PF13558.1 EPE36137.1 - 0.12 12.2 0.0 19 5.2 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EPE36137.1 - 0.35 10.2 1.7 4.3 6.6 0.1 3.0 3 1 1 4 4 4 0 AAA-like domain ABC_ATPase PF09818.4 EPE36137.1 - 1.9 7.0 5.8 14 4.1 0.1 3.4 3 1 0 3 3 3 0 Predicted ATPase of the ABC class IRK PF01007.15 EPE36138.1 - 0.023 13.5 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel SKG6 PF08693.5 EPE36139.1 - 0.00035 19.8 0.6 0.00035 19.8 0.4 2.1 3 0 0 3 3 3 1 Transmembrane alpha-helix domain CFEM PF05730.6 EPE36139.1 - 0.0007 19.3 1.6 0.0015 18.2 1.1 1.5 1 0 0 1 1 1 1 CFEM domain FimP PF09766.4 EPE36139.1 - 0.22 10.5 2.2 0.39 9.7 1.6 1.3 1 0 0 1 1 1 0 Fms-interacting protein SPT2 PF08243.6 EPE36139.1 - 1.6 9.0 8.3 3.8 7.8 5.8 1.6 1 0 0 1 1 1 0 SPT2 chromatin protein His_Phos_2 PF00328.17 EPE36140.1 - 7.1e-19 68.3 0.0 9.7e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EPE36140.1 - 0.0038 17.3 0.0 0.0092 16.0 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) FAD_binding_3 PF01494.14 EPE36141.1 - 7e-11 41.7 0.0 2.8e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EPE36141.1 - 7.6e-08 31.6 0.1 1.3e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPE36141.1 - 1.2e-06 27.6 0.1 0.00018 20.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE36141.1 - 4.5e-06 26.5 0.3 2e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EPE36141.1 - 2.1e-05 23.1 0.1 8e-05 21.2 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EPE36141.1 - 6e-05 23.0 0.4 0.00019 21.4 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPE36141.1 - 8.8e-05 21.7 0.5 0.00013 21.1 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EPE36141.1 - 0.0014 17.5 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EPE36141.1 - 0.0023 18.3 1.1 0.12 12.7 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE36141.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 EPE36141.1 - 0.097 12.0 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.19 EPE36141.1 - 0.098 11.7 0.4 2 7.3 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 EPE36141.1 - 0.18 11.3 2.1 0.2 11.2 0.0 2.0 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.20 EPE36142.1 - 3.1e-14 52.7 0.0 2.9e-13 49.5 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE36142.1 - 0.00013 21.1 0.0 0.00076 18.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase NAD_binding_10 PF13460.1 EPE36143.1 - 1e-22 81.0 0.0 1.8e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE36143.1 - 2.5e-14 53.0 0.0 2.8e-13 49.6 0.0 2.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EPE36143.1 - 3.3e-05 23.4 0.0 0.12 11.7 0.0 3.1 2 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EPE36143.1 - 0.042 14.2 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TraH_2 PF06871.6 EPE36143.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 TraH_2 RmlD_sub_bind PF04321.12 EPE36143.1 - 0.089 11.6 0.0 0.39 9.5 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 EPE36143.1 - 0.1 11.7 0.0 0.33 10.0 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ETF PF01012.16 EPE36143.1 - 0.11 12.2 0.0 3.7 7.2 0.0 2.5 3 0 0 3 3 3 0 Electron transfer flavoprotein domain Fungal_trans_2 PF11951.3 EPE36144.1 - 1.3e-55 188.5 1.3 1.6e-55 188.2 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE36144.1 - 1.6e-09 37.4 9.3 2.8e-09 36.7 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG22 PF11700.3 EPE36145.1 - 1.4e-117 393.1 20.3 1.6e-117 392.9 14.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EPE36145.1 - 2.4e-15 56.0 29.1 1.1e-06 27.6 6.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2684 PF10885.3 EPE36145.1 - 1 9.2 5.8 0.25 11.2 1.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2684) DUF917 PF06032.7 EPE36146.1 - 8.8e-88 294.2 0.0 1.7e-87 293.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EPE36146.1 - 4.7e-45 153.9 8.7 3.4e-43 147.8 2.3 2.8 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EPE36146.1 - 9.6e-37 126.1 0.5 1.3e-32 112.7 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EPE36146.1 - 1.2e-07 30.4 0.7 0.00072 17.9 0.0 2.3 2 0 0 2 2 2 2 MutL protein StbA PF06406.6 EPE36146.1 - 0.0083 15.1 3.5 1.1 8.0 0.1 2.9 4 0 0 4 4 4 2 StbA protein BcrAD_BadFG PF01869.15 EPE36146.1 - 0.039 13.2 0.3 0.039 13.2 0.2 2.6 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 EPE36146.1 - 1.1 9.1 8.0 0.91 9.3 0.4 3.4 3 2 0 3 3 3 0 Cell division protein FtsA CNH PF00780.17 EPE36147.1 - 4.2e-16 59.1 0.0 8.8e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 CNH domain zf-C2H2_4 PF13894.1 EPE36147.1 - 0.017 15.4 22.4 0.61 10.5 1.3 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger PH_5 PF15405.1 EPE36147.1 - 0.069 13.0 1.7 0.07 13.0 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3714 PF12508.3 EPE36147.1 - 0.23 10.9 0.9 3.6 7.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3714) AAA PF00004.24 EPE36149.1 - 9e-48 161.8 0.0 2.7e-42 144.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EPE36149.1 - 2.8e-07 30.1 0.0 3.7e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.1 EPE36149.1 - 4.7e-06 26.7 0.0 0.00081 19.5 0.0 3.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPE36149.1 - 9.5e-06 25.7 0.0 0.00011 22.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EPE36149.1 - 1.6e-05 24.8 0.0 4.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EPE36149.1 - 2.7e-05 23.9 0.0 0.00018 21.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EPE36149.1 - 0.00023 20.6 0.0 0.00099 18.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EPE36149.1 - 0.001 19.1 0.0 0.097 12.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EPE36149.1 - 0.0014 18.8 0.0 0.0089 16.1 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_17 PF13207.1 EPE36149.1 - 0.0016 19.2 0.2 0.017 15.9 0.0 3.0 3 0 0 3 3 1 1 AAA domain AAA_14 PF13173.1 EPE36149.1 - 0.0028 17.5 0.0 0.0085 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPE36149.1 - 0.0058 15.7 0.0 0.024 13.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EPE36149.1 - 0.0074 16.1 0.0 0.046 13.5 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EPE36149.1 - 0.0079 16.1 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPE36149.1 - 0.01 15.5 0.0 0.048 13.4 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EPE36149.1 - 0.014 14.6 0.1 0.05 12.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EPE36149.1 - 0.023 13.4 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Bromodomain PF00439.20 EPE36149.1 - 0.026 14.4 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 Bromodomain Parvo_NS1 PF01057.12 EPE36149.1 - 0.039 12.8 0.0 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EPE36149.1 - 0.044 13.2 0.0 3.3 7.1 0.0 3.0 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 EPE36149.1 - 0.071 12.7 0.1 0.28 10.8 0.1 2.1 2 1 0 2 2 1 0 NACHT domain PhoH PF02562.11 EPE36149.1 - 0.075 12.2 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.1 EPE36149.1 - 0.15 12.4 0.0 0.15 12.4 0.0 3.3 3 0 0 3 3 2 0 AAA domain Foamy_BEL PF03274.9 EPE36150.1 - 0.027 13.6 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein CorA PF01544.13 EPE36150.1 - 0.045 12.7 6.8 0.28 10.1 4.7 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein LMBR1 PF04791.11 EPE36152.1 - 2.8e-29 102.0 3.5 5.5e-29 101.0 2.4 1.3 1 1 0 1 1 1 1 LMBR1-like membrane protein IncA PF04156.9 EPE36152.1 - 0.0075 15.8 0.1 0.0075 15.8 0.0 2.3 2 0 0 2 2 2 1 IncA protein zf-C2H2 PF00096.21 EPE36153.1 - 1.2e-29 100.7 50.8 3.3e-05 23.9 0.1 10.5 11 0 0 11 11 11 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE36153.1 - 4.8e-27 92.2 39.2 0.0041 17.3 0.1 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE36153.1 - 4e-13 48.9 53.3 0.0036 17.5 0.5 10.8 12 1 0 12 12 12 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EPE36153.1 - 9.4e-11 41.5 41.3 0.038 14.1 0.2 9.8 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPE36153.1 - 3.2e-09 36.6 20.8 0.061 13.5 0.1 8.4 9 0 0 9 9 9 3 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EPE36153.1 - 1.3e-07 31.6 29.7 0.12 12.4 0.5 7.6 4 3 4 8 8 8 3 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.16 EPE36153.1 - 0.38 10.6 22.8 12 5.8 6.4 5.7 2 1 1 3 3 3 0 IBR domain zf-C2H2_6 PF13912.1 EPE36153.1 - 0.9 9.5 16.6 14 5.7 0.4 5.6 5 0 0 5 5 5 0 C2H2-type zinc finger CHORD PF04968.7 EPE36153.1 - 2.5 8.4 17.7 39 4.5 0.6 6.0 5 2 2 7 7 7 0 CHORD RNA_pol_Rpb6 PF01192.17 EPE36154.1 - 1.3e-24 85.6 0.4 2.4e-24 84.7 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.7 EPE36154.1 - 0.29 10.8 1.6 0.53 10.0 1.1 1.3 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Esterase PF00756.15 EPE36155.1 - 2.3e-49 168.0 0.0 2.8e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EPE36155.1 - 2.9e-05 23.8 0.0 3.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EPE36155.1 - 0.00019 20.7 0.0 0.012 14.8 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 EPE36155.1 - 0.00065 19.6 0.0 0.00073 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPE36155.1 - 0.0031 16.7 0.0 0.006 15.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EPE36155.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EPE36155.1 - 0.016 14.7 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EPE36155.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 EPE36155.1 - 0.041 13.3 0.1 0.07 12.5 0.0 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 EPE36155.1 - 0.084 11.3 0.0 0.14 10.6 0.0 1.3 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Afi1 PF07792.7 EPE36156.1 - 1.4e-65 219.7 0.0 2.3e-65 219.0 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EPE36156.1 - 1.4e-37 127.8 0.0 2.7e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EPE36156.1 - 7.3e-08 31.2 0.0 0.015 13.8 0.0 3.8 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 EPE36156.1 - 0.016 14.5 0.0 0.14 11.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) EF-hand_6 PF13405.1 EPE36157.1 - 1.1e-12 46.7 0.8 3.5e-06 26.4 0.2 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EPE36157.1 - 8.6e-11 40.3 1.6 9.1e-05 21.4 0.1 2.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EPE36157.1 - 4.1e-08 33.2 0.4 0.0036 17.4 0.1 2.4 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPE36157.1 - 2.7e-06 26.4 3.9 0.00025 20.2 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EPE36157.1 - 2.8e-05 23.6 0.2 0.059 13.0 0.1 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 EPE36157.1 - 0.00048 19.9 0.0 0.045 13.6 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain Whi5 PF08528.6 EPE36158.1 - 6.4e-09 35.1 0.1 1.1e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Whi5 like Dynactin PF12455.3 EPE36158.1 - 0.1 11.5 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Dynein associated protein SSF PF00474.12 EPE36160.1 - 2.9e-18 65.7 23.3 5e-18 64.9 16.2 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Pkinase PF00069.20 EPE36162.1 - 2e-30 105.8 0.0 3.3e-30 105.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE36162.1 - 5.4e-05 22.3 0.0 0.11 11.5 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Methyltransf_16 PF10294.4 EPE36163.1 - 5.8e-14 51.9 0.0 8.4e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EPE36163.1 - 0.029 14.9 0.0 0.046 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EPE36163.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.10 EPE36163.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 zf-C2H2_4 PF13894.1 EPE36164.1 - 0.00025 21.1 14.9 0.11 12.8 0.0 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE36164.1 - 0.00074 19.7 18.3 0.95 9.9 0.0 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPE36164.1 - 0.0037 17.1 0.5 0.15 12.0 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 EPE36164.1 - 0.079 13.1 1.9 4.2 7.7 0.4 3.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF230 PF03003.11 EPE36164.1 - 0.087 12.3 0.8 0.17 11.4 0.6 1.4 1 0 0 1 1 1 0 Poxvirus proteins of unknown function zf-C2H2_jaz PF12171.3 EPE36164.1 - 4 7.6 6.3 37 4.6 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HRXXH PF13933.1 EPE36165.1 - 0.00014 21.3 0.0 0.00021 20.8 0.0 1.3 1 1 0 1 1 1 1 Putative peptidase family zf-rbx1 PF12678.2 EPE36166.1 - 6.1e-11 42.2 0.6 1.3e-10 41.1 0.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPE36166.1 - 2.8e-10 39.8 5.5 7.4e-10 38.4 1.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPE36166.1 - 9e-07 28.4 3.2 1.7e-05 24.3 0.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE36166.1 - 4.5e-06 26.2 0.7 4.1e-05 23.2 0.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPE36166.1 - 1.7e-05 24.3 0.6 5.3e-05 22.7 0.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE36166.1 - 7e-05 22.7 1.7 7e-05 22.7 1.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPE36166.1 - 0.0071 16.1 1.8 0.036 13.8 0.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EPE36166.1 - 0.047 13.4 4.9 0.17 11.6 3.4 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EPE36166.1 - 0.048 13.5 1.0 0.12 12.2 0.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPE36166.1 - 2.6 7.6 3.9 0.74 9.4 0.5 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_transf_8 PF01501.15 EPE36167.1 - 3.2e-35 121.6 0.0 6e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EPE36167.1 - 0.025 13.9 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative PDEase_II PF02112.10 EPE36169.1 - 2.6e-52 177.8 0.0 3.1e-27 95.3 0.0 2.6 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II AMP-binding PF00501.23 EPE36170.1 - 7.2e-55 186.0 0.5 6.7e-29 100.5 0.0 4.7 3 2 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 EPE36170.1 - 2.4e-11 44.1 0.4 6.4e-11 42.8 0.3 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 EPE36170.1 - 0.014 15.2 0.8 0.036 13.8 0.6 1.7 1 0 0 1 1 1 0 Gas vesicle protein G Glycos_transf_1 PF00534.15 EPE36170.1 - 0.22 10.9 0.0 0.43 9.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 K_oxygenase PF13434.1 EPE36173.1 - 3.4e-15 55.8 0.0 5e-09 35.5 0.0 2.5 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EPE36173.1 - 1.2e-11 45.0 0.0 1.9e-05 24.8 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE36173.1 - 1.1e-06 28.4 0.0 0.0098 15.6 0.0 3.8 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.19 EPE36173.1 - 1.1e-05 24.5 0.0 0.67 8.8 0.0 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPE36173.1 - 3.6e-05 23.7 0.0 0.12 12.1 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE36173.1 - 0.022 15.1 0.1 2.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPE36173.1 - 0.023 13.7 0.0 0.069 12.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 EPE36173.1 - 0.038 14.0 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EPE36173.1 - 0.04 14.0 0.0 7.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EPE36173.1 - 0.044 12.6 0.0 0.09 11.6 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EPE36173.1 - 0.071 11.5 0.0 0.31 9.4 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyocin_S PF06958.7 EPE36173.1 - 0.094 13.0 0.4 5 7.4 0.0 2.5 2 0 0 2 2 2 0 S-type Pyocin Lactonase PF10282.4 EPE36174.1 - 2.3e-77 260.4 0.0 2.9e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PS_Dcarbxylase PF02666.10 EPE36175.1 - 3.1e-82 274.7 0.0 1.6e-80 269.2 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NAF PF03822.9 EPE36175.1 - 0.065 12.9 0.2 0.16 11.6 0.2 1.7 1 0 0 1 1 1 0 NAF domain ubiquitin PF00240.18 EPE36176.1 - 2.9e-06 26.5 0.0 8.2e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EPE36176.1 - 5.3e-06 26.5 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EPE36176.1 - 0.14 11.8 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Gtr1_RagA PF04670.7 EPE36177.1 - 3.2e-74 248.9 0.0 4.1e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EPE36177.1 - 0.0015 17.8 0.0 0.0025 17.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EPE36177.1 - 0.0053 17.2 0.0 0.02 15.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein MIF PF01187.13 EPE36178.1 - 4.6e-11 42.8 0.0 7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) BPD_transp_1 PF00528.17 EPE36179.1 - 0.017 14.6 5.6 0.076 12.5 0.5 2.5 2 1 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component MARVEL PF01284.18 EPE36179.1 - 0.022 14.5 8.7 0.038 13.8 5.0 2.0 1 1 1 2 2 2 0 Membrane-associating domain DUF1673 PF07895.6 EPE36179.1 - 0.36 10.3 5.2 0.16 11.5 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) DUF3671 PF12420.3 EPE36179.1 - 9.1 6.3 6.5 48 3.9 4.6 2.1 1 1 0 1 1 1 0 Protein of unknown function PXA PF02194.10 EPE36180.1 - 7.4e-39 133.2 0.0 1.4e-38 132.2 0.0 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 EPE36180.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Sorting nexin C terminal HTH_Tnp_Tc5 PF03221.11 EPE36181.1 - 1.7e-17 62.9 0.0 3.9e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EPE36181.1 - 3e-06 26.5 0.0 5.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 EPE36181.1 - 0.016 14.9 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.1 EPE36181.1 - 0.042 13.6 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_Tnp_4 PF13613.1 EPE36181.1 - 0.075 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease TGS PF02824.16 EPE36182.1 - 2.2e-21 75.4 0.2 5.1e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EPE36182.1 - 1.9e-18 66.4 0.1 4.6e-18 65.2 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE36182.1 - 5.8e-09 35.4 0.0 3.2e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EPE36182.1 - 0.00013 21.4 0.1 1.5 8.1 0.0 3.6 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EPE36182.1 - 0.00044 20.1 0.1 0.073 12.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin family Miro PF08477.8 EPE36182.1 - 0.0024 18.3 0.0 0.0085 16.5 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EPE36182.1 - 0.008 14.9 0.1 0.016 13.9 0.1 1.5 1 0 0 1 1 1 1 ArgK protein 2OG-FeII_Oxy_2 PF13532.1 EPE36184.1 - 2.1e-05 24.4 0.0 2.4e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 EPE36185.1 - 6.6e-41 138.5 3.5 1e-17 64.2 0.0 3.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPE36185.1 - 3.5e-20 70.7 0.4 1e-07 31.3 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EPE36185.1 - 2.2e-18 65.8 1.7 3e-09 36.8 0.0 5.2 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE36185.1 - 7.1e-16 58.2 0.0 4e-06 27.1 0.0 4.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE36185.1 - 4.7e-15 54.1 0.0 3.9e-06 26.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat His_Phos_1 PF00300.17 EPE36186.1 - 2e-21 76.7 0.0 2.5e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-Mss51 PF13824.1 EPE36187.1 - 2.8e-27 94.3 5.2 2.8e-27 94.3 3.6 1.8 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 TPT PF03151.11 EPE36188.1 - 2.3e-16 59.8 14.6 2.3e-16 59.8 10.1 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EPE36188.1 - 0.00014 21.9 10.7 0.00014 21.9 7.4 2.8 2 1 1 3 3 3 1 EamA-like transporter family Tuberculin PF12198.3 EPE36188.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Theoretical tuberculin protein DUF21 PF01595.15 EPE36188.1 - 2 7.6 17.9 0.062 12.5 4.9 3.1 2 2 1 3 3 3 0 Domain of unknown function DUF21 Fungal_trans PF04082.13 EPE36192.1 - 2.6e-10 39.6 0.1 4.6e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE36192.1 - 3.6e-06 26.7 6.3 3.6e-06 26.7 4.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPE36193.1 - 2.4e-29 102.1 23.0 2.4e-29 102.1 16.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE36193.1 - 0.0015 17.2 10.6 0.0015 17.2 7.4 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter CreD PF06123.7 EPE36193.1 - 0.51 8.8 6.8 0.44 9.0 1.9 2.1 2 0 0 2 2 2 0 Inner membrane protein CreD Polysacc_deac_1 PF01522.16 EPE36194.1 - 7.3e-28 96.6 0.0 1.5e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase SH3_9 PF14604.1 EPE36194.1 - 2.3e-06 27.0 0.3 2.3e-06 27.0 0.2 2.2 2 0 0 2 2 2 1 Variant SH3 domain Chitin_bind_1 PF00187.14 EPE36194.1 - 1.6e-05 24.7 57.5 8.6e-05 22.4 17.6 3.0 3 0 0 3 3 3 2 Chitin recognition protein SH3_1 PF00018.23 EPE36194.1 - 4e-05 22.9 0.2 9.2e-05 21.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPE36194.1 - 0.002 17.6 0.1 0.0056 16.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain ZZ PF00569.12 EPE36194.1 - 6.2 6.4 40.8 0.13 11.8 4.4 3.9 3 1 0 3 3 3 0 Zinc finger, ZZ type Methyltransf_23 PF13489.1 EPE36195.1 - 5.8e-16 58.6 0.0 9e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE36195.1 - 8.4e-07 29.3 0.0 6.7e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE36195.1 - 9.7e-07 28.4 0.0 5.4e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE36195.1 - 2e-05 25.1 0.0 0.00025 21.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE36195.1 - 0.00011 22.6 0.0 0.0003 21.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPE36195.1 - 0.0019 17.3 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EPE36195.1 - 0.0037 17.6 0.0 0.013 15.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EPE36195.1 - 0.0041 16.3 0.0 0.0073 15.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 EPE36195.1 - 0.005 15.9 0.0 0.0069 15.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EPE36195.1 - 0.011 15.7 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 EPE36195.1 - 0.027 13.8 0.0 0.089 12.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EPE36195.1 - 0.032 13.3 0.0 0.19 10.8 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EPE36195.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase RgpF PF05045.7 EPE36198.1 - 0.0096 14.4 0.0 0.9 7.9 0.0 2.1 2 0 0 2 2 2 2 Rhamnan synthesis protein F Brix PF04427.13 EPE36199.1 - 1.8e-39 135.3 0.1 2.4e-39 134.9 0.1 1.2 1 0 0 1 1 1 1 Brix domain tRNA-synt_2b PF00587.20 EPE36200.1 - 1.2e-68 230.0 0.0 2e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPE36200.1 - 6e-19 67.7 2.4 1.6e-18 66.3 0.0 2.9 3 0 0 3 3 3 1 Anticodon binding domain Pkinase PF00069.20 EPE36201.1 - 9.9e-71 237.9 0.1 9.9e-71 237.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE36201.1 - 2.8e-53 180.6 0.1 5.1e-53 179.7 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EPE36201.1 - 4.7e-23 81.3 1.2 1.1e-22 80.1 0.1 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EPE36201.1 - 1.2e-07 30.9 0.0 2.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EPE36201.1 - 9e-07 29.1 0.3 4.3e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain APH PF01636.18 EPE36201.1 - 0.0037 17.0 0.1 0.0037 17.0 0.1 3.2 2 2 2 4 4 4 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPE36201.1 - 0.054 12.3 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4337 PF14235.1 EPE36201.1 - 1.5 8.6 6.0 3.7 7.3 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Abhydrolase_6 PF12697.2 EPE36202.1 - 9.5e-18 64.9 0.7 1.1e-17 64.6 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Melibiase PF02065.13 EPE36204.1 - 2e-39 135.4 0.0 8.9e-22 77.3 0.0 2.1 2 0 0 2 2 2 2 Melibiase ABC_tran PF00005.22 EPE36206.1 - 1.7e-52 177.3 0.6 2.6e-29 102.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EPE36206.1 - 3.8e-48 164.2 25.6 2.3e-26 92.8 5.4 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EPE36206.1 - 1.9e-09 37.9 0.1 0.017 15.0 0.0 4.3 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EPE36206.1 - 5.3e-08 32.3 2.2 0.0051 16.0 0.0 3.8 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPE36206.1 - 9.7e-08 32.5 0.1 0.00012 22.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EPE36206.1 - 3.1e-05 23.5 1.3 0.031 13.7 0.0 3.0 2 1 1 3 3 3 2 AAA-like domain AAA_25 PF13481.1 EPE36206.1 - 5.4e-05 22.6 0.1 0.032 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPE36206.1 - 5.5e-05 22.6 0.3 0.29 10.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPE36206.1 - 0.00012 21.3 0.1 0.21 10.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EPE36206.1 - 0.0003 21.5 0.2 1.1 10.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EPE36206.1 - 0.00031 20.6 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 EPE36206.1 - 0.0004 19.3 0.1 0.018 13.9 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 EPE36206.1 - 0.00059 19.7 0.4 0.02 14.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 EPE36206.1 - 0.0007 20.0 0.4 1.8 9.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 EPE36206.1 - 0.0011 19.3 0.1 1.7 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPE36206.1 - 0.0011 18.1 0.6 0.32 10.0 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 EPE36206.1 - 0.0011 18.3 0.1 0.5 9.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EPE36206.1 - 0.0018 17.7 0.1 1 8.8 0.0 2.6 3 0 0 3 3 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 EPE36206.1 - 0.0054 15.3 0.7 0.95 8.0 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 EPE36206.1 - 0.01 16.0 3.2 7 6.7 0.1 3.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EPE36206.1 - 0.012 15.6 3.8 2.6 7.9 0.2 3.3 3 1 0 3 3 2 0 AAA ATPase domain MobB PF03205.9 EPE36206.1 - 0.023 14.4 0.8 10 5.8 0.0 3.3 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EPE36206.1 - 0.036 14.2 1.0 5.2 7.2 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EPE36206.1 - 0.071 12.7 1.6 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 EPE36206.1 - 0.088 12.3 0.2 9.1 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EPE36206.1 - 0.12 11.4 0.2 0.39 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EPE36206.1 - 0.13 12.1 0.0 7.1 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EPE36206.1 - 0.17 11.6 0.0 6.2 6.6 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 EPE36206.1 - 0.18 11.9 0.5 36 4.5 0.0 3.3 3 0 0 3 3 3 0 RNA helicase SecY PF00344.15 EPE36207.1 - 3.5e-96 322.1 11.7 4.4e-96 321.8 8.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EPE36207.1 - 8e-19 66.8 0.4 7.8e-18 63.6 0.2 2.6 2 0 0 2 2 2 1 Plug domain of Sec61p DUF1400 PF07176.6 EPE36207.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) IPPT PF01715.12 EPE36208.1 - 1e-52 178.7 2.2 5.4e-52 176.3 1.5 1.9 1 1 0 1 1 1 1 IPP transferase AAA_33 PF13671.1 EPE36208.1 - 2e-05 24.4 1.7 0.00052 19.9 0.4 3.1 2 1 0 2 2 2 1 AAA domain zf-met PF12874.2 EPE36208.1 - 7.1e-05 22.8 0.3 0.00019 21.5 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_18 PF13238.1 EPE36208.1 - 0.00017 21.8 0.1 0.027 14.7 0.1 3.0 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 EPE36208.1 - 0.00075 18.7 0.0 0.0015 17.7 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase AAA_17 PF13207.1 EPE36208.1 - 0.0016 19.2 0.0 0.0048 17.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPE36208.1 - 0.002 18.1 0.5 0.035 14.0 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain zf-C2H2_jaz PF12171.3 EPE36208.1 - 0.0032 17.5 1.5 0.0064 16.6 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding AAA_19 PF13245.1 EPE36208.1 - 0.014 15.1 0.1 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EPE36208.1 - 0.032 14.3 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EPE36208.1 - 0.036 14.3 0.0 0.17 12.1 0.0 2.2 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EPE36208.1 - 0.046 13.6 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF3744 PF12558.3 EPE36208.1 - 0.052 13.9 0.1 1.8 9.0 0.1 2.4 2 0 0 2 2 2 0 ATP-binding cassette cobalt transporter RNA_helicase PF00910.17 EPE36208.1 - 0.087 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EPE36208.1 - 0.093 12.1 0.0 0.27 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EPE36208.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Hpr_kinase_C PF07475.7 EPE36208.1 - 0.11 11.8 0.1 0.58 9.4 0.0 2.1 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_5 PF07728.9 EPE36208.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-C2H2_2 PF12756.2 EPE36208.1 - 0.15 12.1 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) ORC2 PF04084.9 EPE36209.1 - 1.3e-107 359.4 0.0 1.7e-107 359.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Cut12 PF11500.3 EPE36210.1 - 9.4e-29 100.0 8.6 9.4e-29 100.0 6.0 3.9 4 1 0 4 4 4 1 Spindle pole body formation-associated protein UPF0242 PF06785.6 EPE36210.1 - 0.47 9.0 9.8 0.92 8.1 6.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) TPR_MLP1_2 PF07926.7 EPE36210.1 - 1.8 8.3 26.1 97 2.7 11.1 4.8 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein Cu-oxidase_3 PF07732.10 EPE36211.1 - 7.8e-41 138.5 1.5 2.9e-40 136.6 0.2 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPE36211.1 - 1.4e-37 128.2 1.1 7.8e-33 112.9 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EPE36211.1 - 3.7e-27 95.1 0.0 8.4e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Phosphoesterase PF04185.9 EPE36212.1 - 2.9e-34 118.9 1.4 4.5e-34 118.2 1.0 1.3 1 0 0 1 1 1 1 Phosphoesterase family DUF566 PF04484.7 EPE36213.1 - 0.0093 15.5 0.6 0.011 15.2 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF566) Daxx PF03344.10 EPE36213.1 - 0.029 12.8 5.5 0.034 12.6 3.8 1.0 1 0 0 1 1 1 0 Daxx Family Ebola_NP PF05505.7 EPE36213.1 - 0.15 10.1 5.6 0.17 9.8 3.9 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF605 PF04652.11 EPE36213.1 - 0.48 9.7 4.7 0.52 9.6 3.2 1.1 1 0 0 1 1 1 0 Vta1 like Nop14 PF04147.7 EPE36213.1 - 9.9 3.9 8.9 12 3.6 6.2 1.0 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 EPE36214.1 - 4.9e-12 45.5 0.1 2.4e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE36214.1 - 4.6e-07 29.1 0.1 0.00065 18.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Ank_2 PF12796.2 EPE36215.1 - 2e-15 56.8 1.9 2e-06 28.0 0.0 4.3 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE36215.1 - 6.4e-11 42.4 9.4 0.0022 18.4 0.0 6.5 2 2 5 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.25 EPE36215.1 - 2.2e-10 39.8 5.3 3.9e-06 26.3 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 EPE36215.1 - 2.1e-09 36.7 10.1 0.0041 17.2 0.0 7.8 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.1 EPE36215.1 - 1.5e-07 31.3 4.4 0.00052 20.1 0.0 4.7 4 1 2 6 6 6 2 Ankyrin repeats (many copies) DUF2791 PF10923.3 EPE36215.1 - 0.0088 14.6 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) Zn_clus PF00172.13 EPE36216.1 - 2.5e-05 24.0 1.1 3.4e-05 23.6 0.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF624 PF04854.9 EPE36218.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Gp23 PF07068.6 EPE36218.1 - 0.18 10.2 5.2 0.35 9.3 0.4 2.3 2 0 0 2 2 2 0 Major capsid protein Gp23 DUF605 PF04652.11 EPE36219.1 - 9.7 5.4 16.5 12 5.1 11.4 1.1 1 0 0 1 1 1 0 Vta1 like LicD PF04991.8 EPE36220.1 - 9.4e-35 120.5 5.5 2.7e-33 115.8 3.8 2.1 1 1 0 1 1 1 1 LicD family 4HBT PF03061.17 EPE36221.1 - 5.4e-09 36.0 0.1 8.4e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EPE36221.1 - 0.00036 20.3 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Scm3 PF10384.4 EPE36221.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Centromere protein Scm3 Aldo_ket_red PF00248.16 EPE36222.1 - 1.5e-50 171.6 0.1 2e-50 171.1 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 EPE36223.1 - 3.4e-119 398.3 0.0 4.1e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family MA3 PF02847.12 EPE36223.1 - 0.12 12.0 0.1 0.32 10.7 0.1 1.6 2 0 0 2 2 2 0 MA3 domain DivIVA PF05103.8 EPE36224.1 - 0.014 15.4 5.5 0.023 14.7 2.8 1.8 2 0 0 2 2 2 0 DivIVA protein Pex16 PF08610.5 EPE36224.1 - 0.043 12.8 2.1 0.065 12.2 1.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Flexi_CP PF00286.15 EPE36224.1 - 0.083 12.5 0.2 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Viral coat protein GFA PF04828.9 EPE36225.1 - 5.4e-24 83.9 0.0 6.9e-24 83.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2321 PF10083.4 EPE36225.1 - 0.16 11.4 1.4 3.4 7.1 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) ACBP PF00887.14 EPE36226.1 - 2.1e-28 97.7 0.0 3.7e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Atg14 PF10186.4 EPE36226.1 - 0.0014 17.6 0.2 1 8.2 0.0 2.1 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 UvrB PF12344.3 EPE36226.1 - 0.04 13.4 0.5 0.04 13.4 0.4 2.2 2 0 0 2 2 2 0 Ultra-violet resistance protein B Ribonuclease_3 PF00636.21 EPE36227.1 - 1.3e-14 54.6 0.2 9.1e-14 51.8 0.0 2.4 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EPE36227.1 - 2.5e-09 37.1 0.0 6.5e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EPE36227.1 - 0.00094 19.7 0.4 0.0025 18.3 0.3 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif MRP-S33 PF08293.6 EPE36228.1 - 3.3e-35 119.9 0.5 4.8e-35 119.3 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 SLX9 PF15341.1 EPE36228.1 - 0.018 15.4 1.4 0.02 15.3 0.9 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 PUF PF00806.14 EPE36229.1 - 2.6e-36 121.0 1.3 7e-06 25.2 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.6 EPE36229.1 - 0.017 15.7 0.1 0.9 10.2 0.0 2.9 3 0 0 3 3 3 0 Regulator of ribonuclease activity B LSM14 PF12701.2 EPE36231.1 - 9.1e-34 115.1 0.0 1.8e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EPE36231.1 - 1.1e-19 70.8 0.9 1.1e-19 70.8 0.6 2.0 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 EPE36231.1 - 0.00092 19.0 0.1 0.0023 17.8 0.0 1.7 2 0 0 2 2 2 1 Ataxin 2 SM domain Sugar_tr PF00083.19 EPE36232.1 - 3.7e-88 296.0 31.3 4.4e-88 295.8 21.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE36232.1 - 7.7e-14 51.1 44.2 1.1e-11 44.0 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EPE36233.1 - 7.1e-17 61.0 7.7 4.4e-08 32.1 0.0 3.0 2 1 0 2 2 2 2 Fungal specific transcription factor domain Toxin_16 PF07945.6 EPE36234.1 - 0.0031 17.1 0.3 0.0045 16.6 0.2 1.2 1 0 0 1 1 1 1 Janus-atracotoxin Zn_clus PF00172.13 EPE36235.1 - 2.5e-09 36.8 8.8 3.9e-09 36.2 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE36235.1 - 1.6e-08 33.5 0.1 2.6e-08 32.9 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2781 PF10914.3 EPE36236.1 - 7.6e-14 51.7 8.9 9e-14 51.4 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) ORC6 PF05460.8 EPE36237.1 - 0.1 11.7 6.8 0.12 11.3 4.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Mucin PF01456.12 EPE36237.1 - 0.62 9.8 6.2 1 9.1 4.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein NAM-associated PF14303.1 EPE36237.1 - 7.6 6.8 8.9 22 5.3 6.2 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Myb_DNA-bind_4 PF13837.1 EPE36238.1 - 3.3e-05 23.9 0.0 5.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TBX PF12598.3 EPE36238.1 - 0.0067 16.7 2.7 0.0094 16.3 1.8 1.2 1 0 0 1 1 1 1 T-box transcription factor Myb_DNA-bind_6 PF13921.1 EPE36238.1 - 0.068 13.2 0.1 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 Myb-like DNA-binding domain HTH_12 PF08461.5 EPE36238.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain ORC6 PF05460.8 EPE36238.1 - 0.11 11.6 2.7 0.12 11.4 1.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pox_Ag35 PF03286.9 EPE36239.1 - 0.04 13.4 6.7 0.053 13.0 4.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BSMAP PF12280.3 EPE36240.1 - 0.098 12.5 0.2 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein Pox_Ag35 PF03286.9 EPE36240.1 - 1.7 8.1 8.9 0.63 9.5 4.6 1.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FLO_LFY PF01698.11 EPE36241.1 - 0.06 12.1 1.2 0.072 11.9 0.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4658 PF15555.1 EPE36243.1 - 0.12 12.2 0.0 0.56 10.0 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Cpn60_TCP1 PF00118.19 EPE36244.1 - 6.5e-117 391.1 8.2 7.4e-117 390.9 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.15 EPE36244.1 - 0.041 14.0 0.1 0.14 12.3 0.1 1.9 1 0 0 1 1 1 0 Transcriptional regulator EF1_GNE PF00736.14 EPE36245.1 - 3.4e-32 109.9 1.5 6.2e-32 109.1 1.0 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EPE36245.1 - 2.6e-14 53.0 8.4 2.6e-14 53.0 5.8 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EPE36245.1 - 0.00069 20.0 0.0 0.0019 18.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPE36245.1 - 0.0013 18.7 0.4 0.0046 16.9 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.7 EPE36245.1 - 0.0077 15.9 1.1 0.0098 15.6 0.7 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3752 PF12572.3 EPE36245.1 - 0.17 12.0 3.4 0.29 11.2 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) MMgT PF10270.4 EPE36246.1 - 5.9e-31 107.0 0.0 7.4e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter MutS_V PF00488.16 EPE36247.1 - 7.5e-54 182.6 0.0 3.1e-53 180.6 0.0 1.9 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPE36247.1 - 6.5e-23 81.5 0.0 1.1e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain III ABC2_membrane PF01061.19 EPE36249.1 - 2e-83 278.6 46.4 5.8e-49 166.1 11.9 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPE36249.1 - 7.7e-36 123.4 0.2 7.6e-18 65.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EPE36249.1 - 3.9e-27 93.9 11.9 6.4e-25 86.7 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EPE36249.1 - 2.1e-06 27.6 2.2 2.5e-06 27.4 0.1 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal cobW PF02492.14 EPE36249.1 - 3e-05 23.5 0.1 0.00039 19.9 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 EPE36249.1 - 3.3e-05 24.0 0.1 0.17 11.8 0.0 3.2 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 EPE36249.1 - 3.9e-05 22.9 0.0 0.00058 19.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPE36249.1 - 6.1e-05 22.4 0.5 0.18 11.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 EPE36249.1 - 0.00019 21.2 0.4 0.053 13.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPE36249.1 - 0.0003 20.2 0.1 0.23 10.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EPE36249.1 - 0.00034 20.9 0.1 0.058 13.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EPE36249.1 - 0.00036 20.4 0.3 0.16 11.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EPE36249.1 - 0.00039 21.2 0.0 0.15 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EPE36249.1 - 0.00057 19.4 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.1 EPE36249.1 - 0.0012 18.9 0.8 0.42 10.7 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EPE36249.1 - 0.0014 18.6 1.1 0.036 14.0 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EPE36249.1 - 0.0019 18.2 0.0 0.0066 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EPE36249.1 - 0.0051 16.0 1.5 0.13 11.4 0.0 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 EPE36249.1 - 0.0061 16.1 1.0 0.089 12.4 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EPE36249.1 - 0.0097 15.5 0.5 0.59 9.7 0.2 2.4 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 EPE36249.1 - 0.021 13.7 0.6 1.9 7.2 0.1 3.0 3 0 0 3 3 3 0 NB-ARC domain T2SE PF00437.15 EPE36249.1 - 0.051 12.4 0.2 5.6 5.7 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 EPE36249.1 - 0.071 12.6 0.9 2 7.9 0.2 2.9 3 0 0 3 3 3 0 AAA domain Septin PF00735.13 EPE36249.1 - 0.079 11.9 0.1 0.36 9.8 0.1 1.9 2 0 0 2 2 2 0 Septin AAA_24 PF13479.1 EPE36249.1 - 0.09 12.3 0.4 0.29 10.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EPE36249.1 - 0.11 11.9 0.4 0.36 10.2 0.2 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 EPE36249.1 - 0.12 11.4 0.0 7.7 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EPE36249.1 - 0.19 11.1 2.4 5.8 6.2 0.1 2.9 3 0 0 3 3 2 0 AAA-like domain Dynamin_N PF00350.18 EPE36249.1 - 0.19 11.5 3.1 0.98 9.2 0.0 3.2 4 0 0 4 4 3 0 Dynamin family ArgK PF03308.11 EPE36249.1 - 0.34 9.6 1.7 3.1 6.4 0.1 2.8 3 0 0 3 3 3 0 ArgK protein PLAC8 PF04749.12 EPE36250.1 - 9.3e-20 71.1 21.4 1.1e-19 70.9 14.9 1.1 1 0 0 1 1 1 1 PLAC8 family DUF1752 PF08550.5 EPE36251.1 - 6.6e-08 32.0 3.1 1.3e-07 31.0 2.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CBFB_NFYA PF02045.10 EPE36255.1 - 1.6e-29 102.2 4.3 1.6e-29 102.2 3.0 1.8 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.8 EPE36255.1 - 0.00019 21.4 11.5 0.00024 21.1 8.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-C_C PF11699.3 EPE36256.1 - 6.7e-33 112.5 0.6 1.4e-32 111.5 0.4 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 EPE36256.1 - 2.5e-30 105.8 0.1 2.5e-30 105.8 0.1 4.2 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 EPE36256.1 - 0.00011 21.6 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AT_hook PF02178.14 EPE36256.1 - 4.7 7.2 11.4 10 6.1 1.0 4.0 3 0 0 3 3 3 0 AT hook motif Met_10 PF02475.11 EPE36257.1 - 1.8e-69 233.3 0.0 2.5e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EPE36257.1 - 0.015 15.9 0.0 0.039 14.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 EPE36257.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MethyltransfD12 PF02086.10 EPE36257.1 - 0.06 12.8 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase 2OG-FeII_Oxy_2 PF13532.1 EPE36258.1 - 7.5e-29 100.9 0.0 2.7e-28 99.1 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Prenyltransf PF01255.14 EPE36259.1 - 3.2e-06 26.4 0.0 0.00034 19.8 0.0 2.2 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Sec10 PF07393.6 EPE36260.1 - 1.5e-222 740.7 0.1 1.8e-222 740.4 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Baculo_PEP_C PF04513.7 EPE36260.1 - 1.9 8.2 8.0 0.93 9.3 0.4 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COX17 PF05051.8 EPE36261.1 - 1.3e-19 69.8 5.8 1.6e-19 69.6 4.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) LRR_6 PF13516.1 EPE36262.1 - 2.8e-10 39.1 10.6 0.012 15.6 0.0 7.0 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 EPE36262.1 - 2.6e-06 26.9 15.5 0.0002 20.8 0.2 5.1 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPE36262.1 - 0.00019 21.0 3.5 35 4.9 0.0 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.1 EPE36262.1 - 0.0022 17.6 10.6 0.66 9.7 0.1 4.1 3 1 0 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 EPE36262.1 - 0.52 10.7 2.9 3.8e+02 2.1 0.0 5.0 5 0 0 5 5 5 0 Leucine rich repeat adh_short PF00106.20 EPE36263.1 - 5e-29 101.3 0.1 1.4e-28 99.8 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE36263.1 - 8.8e-13 48.3 0.0 1.8e-12 47.3 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EPE36263.1 - 3.5e-11 43.3 0.1 5.2e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EPE36263.1 - 0.00023 20.1 0.1 0.0003 19.7 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein AIRC PF00731.15 EPE36263.1 - 0.0027 17.0 0.2 0.0099 15.1 0.0 1.9 2 1 0 2 2 2 1 AIR carboxylase tRNA_anti-like PF12869.2 EPE36263.1 - 0.61 9.5 2.7 1.2 8.6 0.2 2.1 1 1 0 2 2 2 0 tRNA_anti-like Mito_carr PF00153.22 EPE36264.1 - 3.9e-53 177.1 2.5 4e-17 61.6 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF4401 PF14351.1 EPE36264.1 - 0.022 13.7 0.1 0.056 12.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) UcrQ PF02939.11 EPE36264.1 - 0.043 13.6 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 UcrQ family DUF2590 PF10761.4 EPE36264.1 - 0.14 11.8 0.0 0.69 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2590) Abp2 PF09441.5 EPE36265.1 - 5.1e-86 287.0 0.0 7.6e-86 286.4 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Adeno_Penton_B PF01686.12 EPE36265.1 - 0.21 9.8 0.0 0.3 9.2 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein DUF4597 PF15366.1 EPE36265.1 - 1.7 8.2 10.7 11 5.6 2.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) Sugar_tr PF00083.19 EPE36266.1 - 8.8e-92 308.0 24.3 1e-91 307.7 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE36266.1 - 2.7e-15 55.9 29.6 2.7e-15 55.9 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EPE36267.1 - 7.2e-75 252.2 0.0 1.2e-59 202.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 WW PF00397.21 EPE36268.1 - 9.4e-08 31.7 0.3 1.7e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 WW domain Pga1 PF10333.4 EPE36269.1 - 0.00032 20.4 0.1 0.0019 17.8 0.0 2.2 2 1 0 2 2 2 1 GPI-Mannosyltransferase II co-activator Tubulin PF00091.20 EPE36270.1 - 1.5e-69 234.1 0.0 2e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPE36270.1 - 7.4e-49 164.9 0.1 1.3e-48 164.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EPE36270.1 - 0.0053 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain MFS_1 PF07690.11 EPE36271.1 - 9e-32 110.1 31.6 9e-32 110.1 21.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3169 PF11368.3 EPE36271.1 - 0.034 13.3 0.4 0.034 13.3 0.3 2.8 4 1 1 5 5 5 0 Protein of unknown function (DUF3169) SH3_1 PF00018.23 EPE36272.1 - 6.4e-38 127.9 8.2 5.7e-14 51.2 0.1 4.1 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EPE36272.1 - 2.4e-37 126.2 7.2 3.2e-12 45.8 0.2 3.5 3 0 0 3 3 3 3 Variant SH3 domain SHD1 PF03983.7 EPE36272.1 - 2.6e-36 123.0 0.1 4.8e-36 122.2 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 EPE36272.1 - 3.7e-26 90.3 1.0 1e-09 37.7 0.0 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 EPE36272.1 - 8.6e-08 32.2 3.3 0.0032 17.6 0.4 3.5 3 0 0 3 3 3 3 Bacterial SH3 domain Cu-oxidase_3 PF07732.10 EPE36274.1 - 3.4e-42 142.8 3.6 1.9e-39 134.0 1.1 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPE36274.1 - 7.2e-40 135.6 5.9 1.2e-37 128.5 0.5 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EPE36274.1 - 1.5e-35 122.4 4.6 1.9e-32 112.4 0.5 2.8 3 0 0 3 3 3 2 Multicopper oxidase PP2C PF00481.16 EPE36274.1 - 6.3e-34 117.5 0.0 2.5e-28 99.1 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EPE36274.1 - 0.0044 16.4 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Cupredoxin_1 PF13473.1 EPE36274.1 - 0.01 15.6 0.0 23 4.9 0.0 3.6 3 1 0 3 3 3 0 Cupredoxin-like domain PPC PF04151.10 EPE36274.1 - 0.018 15.9 0.1 3.1 8.8 0.1 3.0 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain FTR1 PF03239.9 EPE36275.1 - 1.5e-80 270.4 9.6 1.7e-80 270.2 6.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Dor1 PF04124.7 EPE36276.1 - 3.4e-53 180.2 3.4 1.9e-42 144.9 4.9 2.3 2 0 0 2 2 2 2 Dor1-like family Sec5 PF15469.1 EPE36276.1 - 0.007 16.1 0.2 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EPE36276.1 - 0.05 13.4 0.2 0.34 10.7 0.2 2.3 2 0 0 2 2 2 0 Vps51/Vps67 Peptidase_U40 PF10464.4 EPE36278.1 - 0.072 12.5 0.1 6.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase U40 TRAM_LAG1_CLN8 PF03798.11 EPE36279.1 - 2.6e-52 177.2 9.0 2.6e-52 177.2 6.2 1.5 2 0 0 2 2 2 1 TLC domain A_deaminase PF00962.17 EPE36280.1 - 7.4e-113 376.8 0.1 1.1e-112 376.3 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.6 EPE36281.1 - 1e-87 293.9 2.9 1.9e-87 292.9 2.0 1.4 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EPE36281.1 - 0.00044 19.9 3.3 0.00044 19.9 2.3 2.7 3 2 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EPE36281.1 - 0.015 15.3 2.0 0.015 15.3 1.4 3.8 3 2 1 4 4 4 0 EamA-like transporter family EmrE PF13536.1 EPE36281.1 - 0.028 14.6 13.6 0.033 14.4 1.2 3.1 2 1 1 3 3 3 0 Multidrug resistance efflux transporter UPF0546 PF10639.4 EPE36281.1 - 0.036 13.8 1.6 0.19 11.5 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 WD40 PF00400.27 EPE36282.1 - 4.1e-14 51.8 1.3 0.14 12.0 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat PBP PF01161.15 EPE36285.1 - 7.5e-23 81.0 0.2 1e-22 80.5 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Dynamin_M PF01031.15 EPE36286.1 - 4.5e-114 380.2 0.0 1.4e-113 378.6 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EPE36286.1 - 3.2e-56 189.7 0.2 1.5e-55 187.5 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EPE36286.1 - 4.6e-31 106.5 2.1 4.6e-31 106.5 1.4 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EPE36286.1 - 0.00096 19.0 0.2 0.0063 16.4 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPE36286.1 - 0.013 15.9 0.0 0.042 14.3 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 EPE36286.1 - 0.11 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle LtrA PF06772.6 EPE36287.1 - 7.3e-25 87.6 24.0 1.1e-24 87.0 16.6 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Metal_resist PF13801.1 EPE36287.1 - 0.013 15.4 6.7 0.014 15.3 1.4 2.3 1 1 1 2 2 2 0 Heavy-metal resistance Extensin-like_C PF06904.7 EPE36287.1 - 0.034 13.9 0.4 0.12 12.1 0.2 1.8 1 1 1 2 2 2 0 Extensin-like protein C-terminus SBP_bac_11 PF13531.1 EPE36287.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Cep57_CLD_2 PF14197.1 EPE36287.1 - 6.3 6.8 5.9 2.9 7.8 1.6 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Mak10 PF04112.8 EPE36291.1 - 1.5e-50 170.7 0.0 2.8e-50 169.8 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.8 EPE36292.1 - 3.3e-23 80.9 1.7 5.7e-23 80.2 1.2 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16_C PF05193.16 EPE36293.1 - 1.6e-18 67.0 0.0 3e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPE36293.1 - 2.8e-12 46.6 0.0 4.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) RNA_pol_Rpc82 PF05645.8 EPE36294.1 - 3.7e-52 177.4 0.1 2.9e-48 164.6 0.0 2.6 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EPE36294.1 - 2.4e-16 59.3 1.2 6.4e-15 54.7 0.1 3.6 5 0 0 5 5 5 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EPE36294.1 - 5.5e-10 38.6 0.9 7.2e-05 22.2 0.9 3.4 3 0 0 3 3 3 2 TFIIE alpha subunit Cdc6_C PF09079.6 EPE36294.1 - 0.026 14.2 0.0 0.26 11.0 0.0 2.7 3 0 0 3 3 3 0 CDC6, C terminal HTH_20 PF12840.2 EPE36294.1 - 8.8 6.2 9.6 8.5 6.2 0.1 4.7 6 0 0 6 6 6 0 Helix-turn-helix domain Mito_carr PF00153.22 EPE36295.1 - 1.3e-28 98.5 1.7 2.6e-15 55.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2665 PF11654.3 EPE36296.1 - 8.7e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) Atg8 PF02991.11 EPE36298.1 - 3.2e-51 171.6 0.2 3.7e-51 171.4 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EPE36298.1 - 2e-06 27.8 0.0 2.5e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.13 EPE36299.1 - 2.1e-136 453.2 0.2 2.5e-136 453.0 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SWIM PF04434.12 EPE36300.1 - 0.0051 16.2 1.5 0.12 11.9 0.1 2.3 2 0 0 2 2 2 2 SWIM zinc finger MitMem_reg PF13012.1 EPE36301.1 - 1.3e-39 134.8 0.2 2.9e-39 133.7 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EPE36301.1 - 3.3e-27 94.5 0.0 1.1e-26 92.8 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ADK PF00406.17 EPE36302.1 - 1e-57 194.2 0.0 1.4e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EPE36302.1 - 1.5e-14 53.3 0.0 4.9e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EPE36302.1 - 6.2e-06 26.1 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE36302.1 - 2e-05 25.3 0.0 3.1e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPE36302.1 - 0.0017 18.6 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPE36302.1 - 0.011 14.7 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Pol_alpha_B_N PF08418.5 EPE36303.1 - 1.3 8.4 14.8 1.7 8.1 10.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ribosomal_60s PF00428.14 EPE36304.1 - 4.3e-29 100.7 9.6 5e-29 100.5 6.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 EPE36304.1 - 0.074 11.2 0.2 0.071 11.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CTD_bind PF04818.8 EPE36305.1 - 0.00042 20.4 0.0 0.00093 19.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.14 EPE36305.1 - 0.00051 19.6 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 VHS domain zf-C2H2_4 PF13894.1 EPE36305.1 - 0.0037 17.5 5.1 0.7 10.3 0.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE36305.1 - 0.26 11.7 2.4 31 5.1 0.1 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 EPE36305.1 - 0.29 10.8 2.9 8.8 6.1 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SOG2 PF10428.4 EPE36305.1 - 3.4 6.2 7.6 6.5 5.2 5.3 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Inhibitor_I9 PF05922.11 EPE36306.1 - 0.0043 17.5 0.0 0.0066 16.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF3186 PF11382.3 EPE36306.1 - 0.011 14.9 0.1 0.012 14.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) DUF1730 PF08331.5 EPE36306.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) Val_tRNA-synt_C PF10458.4 EPE36306.1 - 0.066 13.2 0.0 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DASH_Dam1 PF08653.5 EPE36307.1 - 1.9 8.3 5.2 50 3.7 0.0 4.4 4 0 0 4 4 4 0 DASH complex subunit Dam1 Tropomyosin_1 PF12718.2 EPE36307.1 - 2.8 7.7 61.7 0.049 13.4 13.3 4.9 2 2 3 5 5 5 0 Tropomyosin like 3HCDH_N PF02737.13 EPE36307.1 - 4.9 6.7 12.5 0.094 12.3 3.0 2.3 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 EPE36308.1 - 3.7e-10 38.9 1.9 4.9e-10 38.5 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE36308.1 - 0.0048 16.7 1.6 0.0078 16.0 1.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_Met_Meta_PP PF01053.15 EPE36309.1 - 5.2e-142 472.7 0.3 5.9e-142 472.5 0.2 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPE36309.1 - 7.4e-08 31.7 0.1 1.1e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPE36309.1 - 9.9e-08 31.1 0.7 2.4e-07 29.8 0.2 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPE36309.1 - 1.5e-07 30.8 0.2 2.8e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EPE36309.1 - 4.6e-05 22.7 0.1 8.7e-05 21.7 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EPE36309.1 - 0.0045 15.7 0.1 0.0072 15.0 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein RNA_pol_Rbc25 PF08292.7 EPE36310.1 - 3.3e-36 124.1 0.0 4.6e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EPE36310.1 - 1.8e-14 53.6 0.0 5.8e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EPE36310.1 - 0.0013 18.8 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain NUFIP1 PF10453.4 EPE36311.1 - 2.1e-08 33.5 0.2 2.1e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EPE36311.1 - 0.078 12.6 5.1 0.17 11.5 3.5 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Dynamin_N PF00350.18 EPE36312.1 - 1.4e-15 57.5 0.0 1.4e-15 57.5 0.0 4.1 4 3 1 5 5 5 1 Dynamin family MMR_HSR1 PF01926.18 EPE36312.1 - 8.4e-07 28.9 0.1 0.00074 19.4 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase IIGP PF05049.8 EPE36312.1 - 2.5e-05 23.2 0.0 0.00049 19.0 0.0 2.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 EPE36312.1 - 0.00052 19.2 0.0 0.0019 17.4 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EPE36312.1 - 0.00063 20.2 0.1 0.0069 16.8 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein SMC_N PF02463.14 EPE36312.1 - 0.00065 18.9 0.0 0.0027 16.9 0.0 2.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EPE36312.1 - 0.0024 16.8 0.0 0.0056 15.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EPE36312.1 - 0.0035 17.6 0.0 0.0035 17.6 0.0 3.8 4 0 0 4 4 4 1 ABC transporter AAA_29 PF13555.1 EPE36312.1 - 0.011 15.2 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EPE36312.1 - 0.031 14.2 1.9 0.14 12.0 0.0 3.0 2 1 1 3 3 3 0 AAA ATPase domain DUF87 PF01935.12 EPE36312.1 - 0.088 12.6 0.1 0.088 12.6 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function DUF87 RRM_1 PF00076.17 EPE36314.1 - 1.2e-13 50.4 0.5 3.3e-09 36.2 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE36314.1 - 1e-11 44.6 0.1 2.7e-07 30.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE36314.1 - 3e-10 39.7 0.1 0.00056 19.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ebola_NP PF05505.7 EPE36314.1 - 0.0034 15.5 24.0 0.0047 15.0 16.7 1.1 1 0 0 1 1 1 1 Ebola nucleoprotein DUF3435 PF11917.3 EPE36314.1 - 2 7.0 8.7 2.9 6.4 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) CHORD PF04968.7 EPE36315.1 - 6.8e-36 122.3 14.0 1.2e-25 89.4 3.8 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EPE36315.1 - 1.4e-11 44.7 0.1 2.5e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 CS domain 2TM PF13239.1 EPE36316.1 - 1.7 8.7 4.9 1.6 8.8 0.3 2.4 2 0 0 2 2 2 0 2TM domain DUF3169 PF11368.3 EPE36316.1 - 2.1 7.5 4.4 1.9 7.6 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) WH2 PF02205.15 EPE36318.1 - 2.8e-10 39.4 0.8 7.9e-10 38.0 0.5 1.9 1 0 0 1 1 1 1 WH2 motif SURF4 PF02077.10 EPE36319.1 - 3e-97 325.1 7.2 3.4e-97 324.9 5.0 1.0 1 0 0 1 1 1 1 SURF4 family DUF1129 PF06570.6 EPE36319.1 - 1.3 8.2 6.3 0.28 10.4 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Halogen_Hydrol PF10112.4 EPE36319.1 - 6.6 6.0 5.7 13 5.0 0.9 2.5 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Sgf11 PF08209.6 EPE36320.1 - 0.0064 15.7 0.1 0.013 14.7 0.1 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DUF3336 PF11815.3 EPE36321.1 - 8.3e-35 119.4 0.0 2.5e-34 117.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EPE36321.1 - 4.5e-16 59.4 0.4 9.2e-16 58.3 0.3 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3237 PF11578.3 EPE36322.1 - 7.5e-28 96.7 0.0 8.6e-28 96.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Mob1_phocein PF03637.12 EPE36323.1 - 4.1e-39 134.0 1.6 4.8e-21 75.1 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 EPE36324.1 - 1.1e-27 96.8 2.0 1.4e-27 96.4 0.0 2.1 2 0 0 2 2 2 1 Leo1-like protein Choline_kinase PF01633.15 EPE36325.1 - 4e-53 180.1 0.0 6.2e-52 176.2 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EPE36325.1 - 1.6e-11 44.3 0.0 4.7e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EPE36325.1 - 0.00092 18.4 0.0 0.0076 15.4 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EPE36325.1 - 0.1 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Baculo_p33 PF05214.7 EPE36325.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Baculovirus P33 Voltage_CLC PF00654.15 EPE36326.1 - 7.5e-88 294.9 15.4 7.5e-88 294.9 10.6 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EPE36326.1 - 0.00071 19.3 0.1 0.0024 17.6 0.0 2.0 2 0 0 2 2 2 1 CBS domain PsbX PF06596.6 EPE36326.1 - 0.073 12.7 1.2 1.8 8.3 0.0 3.5 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) DUF3425 PF11905.3 EPE36327.1 - 3.5e-14 52.8 0.1 1.1e-13 51.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EPE36327.1 - 9.2e-06 25.5 19.3 2.4e-05 24.1 13.4 1.7 1 1 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 EPE36327.1 - 0.046 13.4 0.0 0.046 13.4 0.0 2.4 2 1 0 2 2 2 0 Homeobox associated leucine zipper bZIP_Maf PF03131.12 EPE36327.1 - 0.16 12.2 12.8 0.34 11.2 8.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DltD_C PF04914.7 EPE36327.1 - 0.2 11.5 0.9 0.37 10.6 0.6 1.4 1 0 0 1 1 1 0 DltD C-terminal region bZIP_2 PF07716.10 EPE36327.1 - 4.2 7.2 24.5 8.5 6.2 4.1 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Zn_clus PF00172.13 EPE36328.1 - 2.1e-05 24.3 9.8 3.7e-05 23.5 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BOP1NT PF08145.7 EPE36329.1 - 4.5e-106 354.3 6.9 6.5e-106 353.8 4.8 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EPE36329.1 - 3.8e-24 83.6 2.2 1.5e-11 43.7 0.2 6.6 8 0 0 8 8 8 4 WD domain, G-beta repeat RNase_HII PF01351.13 EPE36330.1 - 8.8e-45 152.7 0.0 2e-44 151.6 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease HII Fructosamin_kin PF03881.9 EPE36331.1 - 9e-64 215.2 0.0 1.1e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EPE36331.1 - 9.5e-07 28.7 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_4 PF12763.2 EPE36332.1 - 3.3e-33 113.5 0.0 4.3e-14 52.1 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 EPE36332.1 - 1.9e-06 27.5 0.1 4.1e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 EPE36332.1 - 5.9e-06 26.3 0.0 0.013 15.5 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair Macoilin PF09726.4 EPE36332.1 - 0.0061 14.9 24.0 0.012 13.9 16.6 1.3 1 0 0 1 1 1 1 Transmembrane protein IncA PF04156.9 EPE36332.1 - 0.16 11.5 35.5 0.19 11.3 13.9 2.2 1 1 1 2 2 2 0 IncA protein Vac_Fusion PF02346.11 EPE36332.1 - 0.21 11.0 0.3 3.4 7.1 0.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus fusion protein CENP-F_leu_zip PF10473.4 EPE36332.1 - 2.5 7.9 31.1 0.28 11.0 12.5 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 EPE36332.1 - 3.3 7.8 21.9 2.6 8.1 6.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 EPE36332.1 - 3.7 7.3 36.1 8 6.2 9.7 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Occludin_ELL PF07303.8 EPE36332.1 - 4.3 8.1 16.6 15 6.3 3.4 2.9 1 1 1 2 2 2 0 Occludin homology domain CorA PF01544.13 EPE36333.1 - 7.5e-05 21.8 0.7 0.002 17.2 0.0 2.8 1 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Acetyltransf_1 PF00583.19 EPE36334.1 - 8.6e-09 35.3 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE36334.1 - 4.4e-07 29.9 0.0 7.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE36334.1 - 3.7e-05 23.3 0.0 7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPE36334.1 - 9.1e-05 22.5 0.0 0.00018 21.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPE36334.1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE36334.1 - 0.0012 18.7 0.1 0.0082 16.0 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPE36334.1 - 0.041 14.0 0.0 0.077 13.1 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE36334.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CFEM PF05730.6 EPE36335.1 - 3.1e-07 30.0 7.7 6.6e-07 29.0 5.3 1.5 1 0 0 1 1 1 1 CFEM domain CDC45 PF02724.9 EPE36336.1 - 0.0065 14.5 29.7 0.12 10.3 1.7 2.3 2 0 0 2 2 2 2 CDC45-like protein Zip PF02535.17 EPE36336.1 - 0.44 9.4 14.5 0.94 8.4 5.9 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 EPE36336.1 - 4.6 7.0 20.2 0.66 9.8 3.9 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 LZ_Tnp_IS66 PF13007.2 EPE36336.1 - 6.6 7.4 16.1 4.4 8.0 1.6 2.9 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Myc_N PF01056.13 EPE36336.1 - 6.9 5.7 18.0 2.2 7.3 0.5 2.4 2 0 0 2 2 2 0 Myc amino-terminal region WD40 PF00400.27 EPE36337.1 - 8.7e-52 171.2 10.9 2.5e-09 36.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EPE36337.1 - 3.5e-14 51.7 3.0 6.5e-14 50.8 2.1 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EPE36337.1 - 0.072 12.7 0.0 14 5.3 0.0 3.4 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A Sugar_tr PF00083.19 EPE36341.1 - 1.6e-23 82.9 25.1 1.8e-14 53.2 4.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter CorA PF01544.13 EPE36342.1 - 1.2e-13 50.7 2.0 2.2e-13 49.9 1.4 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.9 EPE36342.1 - 0.002 17.4 0.2 0.0047 16.2 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPE36342.1 - 0.0026 17.6 0.0 0.0057 16.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPE36342.1 - 0.062 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.7 EPE36342.1 - 0.073 12.5 0.4 0.28 10.6 0.0 2.1 2 1 1 3 3 3 0 Alpha/beta hydrolase E1-E2_ATPase PF00122.15 EPE36342.1 - 0.27 10.2 0.4 0.47 9.4 0.3 1.3 1 0 0 1 1 1 0 E1-E2 ATPase FdhE PF04216.7 EPE36342.1 - 0.8 9.3 5.0 1.9 8.1 3.4 1.5 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation IncA PF04156.9 EPE36342.1 - 1.6 8.2 10.4 5.8 6.4 7.2 1.9 1 0 0 1 1 1 0 IncA protein tRNA_anti-codon PF01336.20 EPE36343.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Pkinase PF00069.20 EPE36344.1 - 1.9e-61 207.4 0.0 4.4e-61 206.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE36344.1 - 6.4e-30 104.0 0.0 1.2e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EPE36344.1 - 2.1e-08 34.1 0.2 1.9e-06 27.9 0.1 2.6 2 0 0 2 2 2 1 FHA domain APH PF01636.18 EPE36344.1 - 0.0013 18.4 0.0 0.64 9.7 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family COesterase PF00135.23 EPE36345.1 - 3e-104 349.6 0.0 4e-104 349.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EPE36345.1 - 0.00012 21.4 0.2 0.00018 20.8 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EPE36345.1 - 0.00041 20.0 0.2 0.0022 17.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold GPI-anchored PF10342.4 EPE36346.1 - 7.4e-13 48.8 0.1 7.4e-13 48.8 0.0 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 EPE36348.1 - 2e-17 63.4 4.3 2e-17 63.4 3.0 3.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family VP4_haemagglut PF00426.13 EPE36348.1 - 3.7 5.3 19.5 4.5 5.1 13.5 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) Ribul_P_3_epim PF00834.14 EPE36349.1 - 3.4e-64 215.6 0.0 2.8e-63 212.6 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 EPE36349.1 - 0.035 13.4 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Amidohydro_2 PF04909.9 EPE36349.1 - 0.056 13.0 0.0 0.17 11.4 0.0 1.8 1 1 1 2 2 2 0 Amidohydrolase ThiG PF05690.9 EPE36349.1 - 0.076 12.0 0.1 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PcrB PF01884.12 EPE36349.1 - 0.08 12.1 0.1 0.16 11.1 0.0 1.5 1 1 0 1 1 1 0 PcrB family p450 PF00067.17 EPE36350.1 - 3.8e-94 315.8 0.0 4.5e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ofd1_CTDD PF10637.4 EPE36352.1 - 2.1e-93 312.2 14.4 1e-87 293.6 9.6 2.4 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EPE36352.1 - 1.8e-14 54.0 0.0 6.7e-14 52.2 0.0 2.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EPE36352.1 - 0.019 14.5 0.0 0.056 13.0 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aminotran_5 PF00266.14 EPE36353.1 - 6.5e-56 189.6 0.0 7.5e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EPE36353.1 - 7e-05 21.2 0.0 0.00014 20.2 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPE36353.1 - 0.0068 15.4 0.0 0.0099 14.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II p450 PF00067.17 EPE36354.1 - 2.5e-43 148.2 0.0 3.4e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAM196 PF15265.1 EPE36364.1 - 9 5.3 27.2 12 4.9 18.8 1.3 1 0 0 1 1 1 0 FAM196 family WD40 PF00400.27 EPE36365.1 - 2.2e-20 71.6 7.3 1.2e-06 28.2 0.0 6.7 8 0 0 8 8 8 5 WD domain, G-beta repeat Dynein_IC2 PF11540.3 EPE36365.1 - 0.1 12.0 0.0 1.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 ATP-synt_E PF05680.7 EPE36366.1 - 1.8e-21 75.8 0.1 1.8e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase E chain STT3 PF02516.9 EPE36367.1 - 3.8e-131 438.3 35.1 6.2e-126 421.1 23.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit TPR_11 PF13414.1 EPE36369.1 - 6.5e-24 83.3 5.4 1.2e-09 37.6 0.9 4.4 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 EPE36369.1 - 2.1e-20 70.9 2.4 2.4e-05 23.9 0.1 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EPE36369.1 - 1.4e-19 68.7 2.6 3.4e-06 26.4 0.0 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EPE36369.1 - 4.6e-15 54.7 5.3 0.0014 19.0 0.1 6.2 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPE36369.1 - 1.3e-13 50.6 8.8 3.5e-08 33.2 0.5 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPE36369.1 - 1.3e-13 51.1 5.1 9.8e-05 22.9 0.2 4.6 2 2 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPE36369.1 - 2.1e-13 50.3 5.2 0.0012 19.1 1.2 4.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPE36369.1 - 7.6e-13 47.5 1.2 0.073 13.3 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EPE36369.1 - 1.4e-12 46.3 2.6 0.0029 17.3 0.1 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPE36369.1 - 8.5e-11 40.8 0.1 0.001 18.6 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 EPE36369.1 - 2.2e-10 40.4 0.8 0.0022 18.0 0.0 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EPE36369.1 - 1.1e-07 31.5 1.9 0.043 13.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EPE36369.1 - 1.8e-06 27.9 2.5 5.5e-05 23.2 0.4 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EPE36369.1 - 1.2e-05 25.4 3.3 2.8 8.6 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.13 EPE36369.1 - 0.016 15.0 1.6 6.9 6.6 0.2 4.7 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 EPE36369.1 - 0.026 14.3 0.0 7.2 6.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1992 PF09350.5 EPE36369.1 - 0.032 14.0 1.1 2 8.2 0.0 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF1992) TPR_10 PF13374.1 EPE36369.1 - 0.037 13.9 8.1 0.13 12.2 0.2 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat RRM_1 PF00076.17 EPE36370.1 - 3e-36 122.8 1.3 2.4e-18 65.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE36370.1 - 5.1e-26 90.4 0.4 5.8e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE36370.1 - 5.4e-14 51.7 0.1 2.8e-07 30.2 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HLH PF00010.21 EPE36371.1 - 3.3e-13 49.0 0.4 8.1e-13 47.8 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF972 PF06156.8 EPE36371.1 - 0.073 13.4 0.3 0.27 11.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EPE36371.1 - 0.084 13.1 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TMF_TATA_bd PF12325.3 EPE36371.1 - 0.13 11.9 3.1 0.096 12.4 0.6 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 EPE36371.1 - 0.16 11.1 0.5 0.31 10.1 0.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EPE36371.1 - 1.9 8.3 7.9 0.98 9.3 0.4 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CAP59_mtransfer PF11735.3 EPE36372.1 - 4.2e-74 248.8 0.0 7.4e-74 248.0 0.0 1.3 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 p450 PF00067.17 EPE36373.1 - 6.2e-41 140.3 0.0 8.4e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TspO_MBR PF03073.10 EPE36374.1 - 2.6e-40 137.3 4.1 3.2e-40 137.0 2.9 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF3382 PF11862.3 EPE36375.1 - 4 7.4 8.5 74 3.3 5.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3382) Acetyltransf_1 PF00583.19 EPE36377.1 - 5.4e-07 29.5 0.0 9.8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE36377.1 - 3.3e-05 23.9 0.0 6.1e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPE36377.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EPE36377.1 - 0.054 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.13 EPE36377.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family DUF4187 PF13821.1 EPE36378.1 - 2.1e-25 88.0 0.1 5e-25 86.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 EPE36378.1 - 1.2e-23 83.2 2.2 1.2e-23 83.2 1.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EPE36378.1 - 1.6e-08 35.0 0.3 4.5e-08 33.5 0.2 1.8 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Tubulin PF00091.20 EPE36379.1 - 1.3e-66 224.4 0.0 1.7e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPE36379.1 - 8.9e-42 142.1 0.0 1.4e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EPE36379.1 - 0.0037 16.7 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Cpn60_TCP1 PF00118.19 EPE36380.1 - 8.9e-137 456.6 14.5 1.1e-136 456.3 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EPE36380.1 - 0.028 13.8 0.0 0.074 12.5 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X AAA PF00004.24 EPE36381.1 - 1e-40 138.9 0.0 1.7e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE36381.1 - 4.8e-06 26.7 0.0 0.00059 19.9 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPE36381.1 - 4.7e-05 23.1 0.0 0.00026 20.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPE36381.1 - 0.00012 22.0 0.0 0.00044 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPE36381.1 - 0.00029 20.8 0.0 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EPE36381.1 - 0.0018 17.2 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EPE36381.1 - 0.004 17.9 0.1 0.013 16.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPE36381.1 - 0.0084 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EPE36381.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EPE36381.1 - 0.021 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPE36381.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPE36381.1 - 0.032 14.0 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPE36381.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EPE36381.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EPE36381.1 - 0.071 12.1 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EPE36381.1 - 0.085 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EPE36381.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EPE36381.1 - 0.11 12.1 0.0 8.2 6.0 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase AAA_25 PF13481.1 EPE36381.1 - 0.13 11.6 0.3 0.48 9.7 0.0 1.9 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EPE36381.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF3818 PF12825.2 EPE36382.1 - 8.1e-135 448.8 5.6 1.2e-134 448.3 3.9 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EPE36382.1 - 7.1e-42 142.2 1.8 1.4e-41 141.2 1.3 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EPE36382.1 - 4.4e-16 58.6 0.5 1.2e-14 54.0 0.0 3.3 4 1 0 4 4 4 1 PX domain MCPsignal PF00015.16 EPE36383.1 - 0.032 13.7 0.9 0.066 12.7 0.5 1.5 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fib_alpha PF08702.5 EPE36383.1 - 0.11 12.6 3.5 0.2 11.7 1.1 2.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Med9 PF07544.8 EPE36383.1 - 0.17 11.6 1.6 10 5.9 0.0 3.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Syntaxin-6_N PF09177.6 EPE36383.1 - 2.9 8.3 5.7 1.5 9.2 1.4 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cgr1 PF03879.9 EPE36384.1 - 1.4e-36 124.9 35.5 1.7e-36 124.7 24.6 1.0 1 0 0 1 1 1 1 Cgr1 family Pal1 PF08316.6 EPE36384.1 - 3.3 8.1 5.6 4.2 7.8 3.9 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein SNF5 PF04855.7 EPE36384.1 - 5.3 6.4 10.1 6.7 6.1 7.0 1.1 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 GAGA_bind PF06217.7 EPE36384.1 - 6.6 6.5 16.9 7.6 6.4 11.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CDC27 PF09507.5 EPE36384.1 - 7.9 5.5 25.6 8.7 5.4 17.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Asp-B-Hydro_N PF05279.6 EPE36384.1 - 7.9 6.2 16.6 8.4 6.1 11.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mito_carr PF00153.22 EPE36385.1 - 3.9e-61 202.7 0.3 5.3e-20 70.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Exo_endo_phos PF03372.18 EPE36386.1 - 2e-10 41.0 0.0 2.9e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 5_nucleotid_C PF02872.13 EPE36387.1 - 6e-31 107.5 0.1 1.5e-30 106.2 0.1 1.7 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EPE36387.1 - 1.4e-08 34.4 0.9 4.6e-08 32.6 0.6 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.1 EPE36387.1 - 0.0073 15.3 0.1 0.018 14.0 0.1 1.7 2 0 0 2 2 2 1 YmdB-like protein DUF3425 PF11905.3 EPE36388.1 - 8.5e-31 106.6 0.7 1.5e-30 105.8 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EPE36388.1 - 0.36 10.8 7.2 0.66 9.9 5.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor HET PF06985.6 EPE36389.1 - 1.7e-21 76.8 1.1 3.8e-21 75.6 0.8 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldedh PF00171.17 EPE36390.1 - 6.8e-139 463.1 0.0 8.4e-139 462.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPE36390.1 - 0.00029 19.6 0.0 0.0019 16.9 0.0 2.3 1 1 1 2 2 2 1 Acyl-CoA reductase (LuxC) zf-MYND PF01753.13 EPE36391.1 - 7e-11 41.8 10.8 7e-11 41.8 7.5 1.8 2 0 0 2 2 2 1 MYND finger SET PF00856.23 EPE36391.1 - 2.1e-08 34.6 0.0 2.2e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 SET domain HET PF06985.6 EPE36392.1 - 1.9e-28 99.3 0.4 4.3e-28 98.2 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_C97 PF05903.9 EPE36393.1 - 1.3e-06 28.2 0.0 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EPE36393.1 - 0.00061 19.7 0.0 0.0019 18.1 0.0 1.7 2 0 0 2 2 2 1 Lecithin retinol acyltransferase FAD_binding_2 PF00890.19 EPE36394.1 - 4.4e-126 421.1 2.4 5.5e-126 420.7 1.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EPE36394.1 - 9.6e-46 154.8 0.4 1.4e-45 154.2 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EPE36394.1 - 1.2e-06 28.5 0.2 0.0021 17.9 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPE36394.1 - 9.9e-06 24.6 1.4 0.014 14.2 1.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EPE36394.1 - 1.1e-05 24.6 0.3 0.0079 15.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EPE36394.1 - 0.00014 20.8 0.1 0.0034 16.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPE36394.1 - 0.0049 15.9 0.9 0.0076 15.3 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EPE36394.1 - 0.092 11.1 1.8 0.21 10.0 0.2 2.2 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.1 EPE36394.1 - 0.16 11.9 1.8 1.1 9.2 0.2 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EPE36395.1 - 3.2e-25 88.8 0.1 7.1e-25 87.7 0.1 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE36395.1 - 5.8e-18 65.5 0.1 1.2e-17 64.5 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.13 EPE36395.1 - 5.6e-08 32.3 1.7 5.6e-08 32.3 1.2 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain DAO PF01266.19 EPE36395.1 - 2.6e-06 26.6 0.4 1.9e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE36395.1 - 1.7e-05 23.8 0.6 0.0015 17.4 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EPE36395.1 - 0.00011 20.8 0.3 0.00024 19.7 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EPE36395.1 - 0.00053 20.1 0.2 0.02 14.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE36395.1 - 0.0013 18.7 0.1 0.0059 16.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPE36395.1 - 0.0093 16.3 0.2 0.21 12.0 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPE36395.1 - 0.013 14.3 0.2 0.21 10.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EPE36395.1 - 0.015 14.2 0.2 0.03 13.2 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPE36395.1 - 0.019 14.8 0.3 0.075 12.9 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPE36395.1 - 0.057 12.4 0.1 0.092 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EPE36395.1 - 0.11 11.5 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 EPE36395.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain ELMO_CED12 PF04727.8 EPE36396.1 - 3.5e-49 166.6 0.1 7.4e-49 165.5 0.0 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EPE36396.1 - 2e-05 24.3 0.1 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) MS_channel PF00924.13 EPE36397.1 - 1.5e-22 80.0 1.0 2.6e-22 79.1 0.7 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EPE36397.1 - 0.0021 17.2 0.2 0.0056 15.8 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EPE36397.1 - 0.0024 17.9 0.2 0.0061 16.6 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPE36397.1 - 0.0034 17.1 0.0 0.011 15.5 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EPE36397.1 - 0.049 12.9 0.0 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 EF hand DUF3671 PF12420.3 EPE36397.1 - 4.1 7.4 7.9 1.6 8.7 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function APH PF01636.18 EPE36398.1 - 3.6e-13 49.7 0.1 8.8e-13 48.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE36398.1 - 0.028 13.9 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EPE36398.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) TB2_DP1_HVA22 PF03134.14 EPE36398.1 - 0.26 11.0 1.5 0.51 10.1 1.0 1.5 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Abhydrolase_6 PF12697.2 EPE36399.1 - 2.1e-14 53.9 6.6 4e-14 53.0 4.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE36399.1 - 2.4e-11 43.5 0.4 4e-11 42.8 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE36399.1 - 6.3e-07 29.1 0.1 8.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EPE36399.1 - 1.8e-05 24.4 0.3 2.5e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPE36399.1 - 0.0086 15.3 0.3 0.017 14.3 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EPE36399.1 - 0.057 13.2 0.1 0.17 11.7 0.1 1.8 1 1 0 1 1 1 0 Putative lysophospholipase zf-GRF PF06839.7 EPE36401.1 - 3.2e-11 42.9 4.1 6.3e-11 42.0 2.9 1.5 1 0 0 1 1 1 1 GRF zinc finger TcdA_TcdB PF12919.2 EPE36401.1 - 0.038 12.4 0.8 0.053 12.0 0.5 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain BMFP PF04380.8 EPE36401.1 - 0.052 13.6 2.4 0.13 12.4 1.7 1.6 1 0 0 1 1 1 0 Membrane fusogenic activity TSC22 PF01166.13 EPE36401.1 - 0.16 11.9 0.9 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF563 PF04577.9 EPE36402.1 - 1.2e-24 87.4 0.0 2.4e-24 86.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF563) PHP PF02811.14 EPE36402.1 - 0.031 14.0 0.0 0.079 12.7 0.0 1.7 2 0 0 2 2 2 0 PHP domain Yippee-Mis18 PF03226.9 EPE36403.1 - 6.5e-06 26.1 0.8 0.0002 21.3 0.0 2.7 2 1 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.4 EPE36403.1 - 0.14 10.8 6.0 0.34 9.5 0.0 2.9 3 0 0 3 3 3 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GAS PF13851.1 EPE36403.1 - 0.22 10.7 7.9 0.44 9.7 5.5 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GFA PF04828.9 EPE36403.1 - 0.63 10.0 3.0 6.8 6.7 0.2 3.0 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme EAP30 PF04157.11 EPE36403.1 - 1 8.4 8.9 5.1 6.1 0.2 2.9 1 1 0 2 2 2 0 EAP30/Vps36 family C1_4 PF07975.7 EPE36403.1 - 1.8 8.6 5.9 2.4 8.2 0.0 3.0 2 1 0 2 2 2 0 TFIIH C1-like domain RNase_T PF00929.19 EPE36404.1 - 1.9e-23 83.5 0.0 4.2e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Exonuclease Catalase PF00199.14 EPE36406.1 - 2.9e-160 533.1 0.2 3.8e-160 532.7 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EPE36406.1 - 5.7e-15 54.9 0.1 1.4e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EPE36406.1 - 0.0014 18.0 0.1 0.0033 16.8 0.1 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family His_Phos_1 PF00300.17 EPE36407.1 - 1.4e-19 70.7 0.0 1.9e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NACHT PF05729.7 EPE36408.1 - 6.5e-10 38.9 0.0 1.9e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EPE36408.1 - 0.00014 22.0 0.0 0.0005 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPE36408.1 - 0.01 16.1 0.6 0.033 14.4 0.0 2.1 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 EPE36408.1 - 0.013 15.4 0.1 0.086 12.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 EPE36408.1 - 0.038 12.8 0.0 0.11 11.3 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 EPE36408.1 - 0.049 13.0 0.8 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EPE36408.1 - 0.06 13.6 0.1 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EPE36408.1 - 0.1 12.1 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EPE36408.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Ank PF00023.25 EPE36408.1 - 0.13 12.1 0.0 0.7 9.8 0.0 2.4 1 1 0 1 1 1 0 Ankyrin repeat IBR PF01485.16 EPE36409.1 - 1.3e-11 44.1 35.9 6.3e-08 32.3 3.9 3.1 3 0 0 3 3 3 2 IBR domain CFEM PF05730.6 EPE36410.1 - 8.3e-16 57.5 14.4 1.3e-15 56.9 10.0 1.3 1 0 0 1 1 1 1 CFEM domain Methyltransf_23 PF13489.1 EPE36411.1 - 7.1e-15 55.0 0.0 9.3e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE36411.1 - 3.3e-13 49.4 0.0 4.2e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE36411.1 - 8.2e-10 39.0 0.0 1.3e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE36411.1 - 6.1e-09 36.2 0.0 1.2e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE36411.1 - 6.5e-09 36.0 0.0 1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE36411.1 - 2e-08 34.8 0.0 3.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE36411.1 - 1.2e-05 24.7 0.1 2.6e-05 23.6 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EPE36411.1 - 2.3e-05 23.6 0.0 3.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EPE36411.1 - 0.00031 20.7 0.0 0.00059 19.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EPE36411.1 - 0.0027 16.6 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase LMWSLP_N PF12211.3 EPE36411.1 - 0.026 14.3 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Low molecular weight S layer protein N terminal AdoMet_MTase PF07757.8 EPE36411.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase HET PF06985.6 EPE36412.1 - 6.6e-17 61.9 0.0 1.9e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) SUI1 PF01253.17 EPE36413.1 - 4.1e-23 80.9 0.2 7.7e-23 80.1 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Nbl1_Borealin_N PF10444.4 EPE36414.1 - 8.4e-22 76.3 1.9 8.4e-22 76.3 1.3 1.8 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 EPE36415.1 - 8e-16 58.6 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EPE36415.1 - 9.8e-10 38.4 0.2 1.4e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EPE36415.1 - 4.7e-08 32.8 0.0 6.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EPE36415.1 - 0.00053 19.3 1.5 0.0016 17.8 1.1 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif RNA_pol_Rpb4 PF03874.11 EPE36416.1 - 1.7e-26 92.5 3.4 2.1e-26 92.1 2.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 HLH PF00010.21 EPE36416.1 - 0.074 12.7 0.1 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Mid2 PF04478.7 EPE36418.1 - 0.034 13.5 0.1 0.066 12.6 0.1 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.1 EPE36418.1 - 0.094 12.4 0.2 0.3 10.7 0.2 1.8 1 0 0 1 1 1 0 TMEM154 protein family ADH_N PF08240.7 EPE36419.1 - 2.8e-21 75.3 2.1 5.8e-21 74.3 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPE36419.1 - 4e-12 45.8 0.0 7e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPE36419.1 - 0.0002 20.5 0.1 0.00032 19.8 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EPE36419.1 - 0.0033 17.0 0.1 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.17 EPE36419.1 - 0.04 14.4 0.0 0.068 13.6 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.10 EPE36419.1 - 0.082 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EPE36419.1 - 0.094 12.3 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_45 PF02015.11 EPE36420.1 - 4e-87 291.4 22.4 4e-87 291.4 15.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 EPE36420.1 - 1.7e-11 43.5 9.2 1.7e-11 43.5 6.4 4.2 4 0 0 4 4 4 1 Fungal cellulose binding domain Orthopox_35kD PF02250.10 EPE36422.1 - 0.0048 16.2 0.7 0.007 15.7 0.5 1.2 1 0 0 1 1 1 1 35kD major secreted virus protein Alpha_GJ PF03229.8 EPE36422.1 - 0.012 15.9 11.4 0.012 15.9 7.9 1.9 2 0 0 2 2 2 0 Alphavirus glycoprotein J Amnionless PF14828.1 EPE36422.1 - 0.049 12.1 0.0 0.063 11.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless TrbL PF04610.9 EPE36422.1 - 0.078 12.6 1.2 0.11 12.2 0.9 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Alg6_Alg8 PF03155.10 EPE36423.1 - 8.5e-133 443.5 23.0 4.3e-84 283.0 4.1 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family MFS_1 PF07690.11 EPE36424.1 - 1.1e-39 136.1 51.4 1.1e-39 136.1 35.6 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE36424.1 - 8.7e-11 41.0 15.3 8.7e-11 41.0 10.6 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter Ank_2 PF12796.2 EPE36426.1 - 1.2e-52 176.1 0.0 2.2e-17 63.1 0.0 4.6 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EPE36426.1 - 1.9e-37 125.1 7.6 1.1e-06 28.1 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 EPE36426.1 - 1.2e-32 108.7 1.2 3.9e-05 23.4 0.0 8.4 7 1 1 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EPE36426.1 - 2.7e-31 107.3 3.1 6.6e-08 32.8 0.0 6.2 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPE36426.1 - 1.2e-28 98.4 4.2 0.00012 22.1 0.0 7.5 5 2 3 8 8 8 7 Ankyrin repeats (many copies) NmrA PF05368.8 EPE36427.1 - 1e-47 162.3 0.9 1.2e-47 162.0 0.6 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE36427.1 - 1.8e-13 50.8 0.0 2.6e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE36427.1 - 1.2e-07 30.7 0.0 1.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE36427.1 - 0.024 14.0 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EPE36427.1 - 0.12 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans_2 PF11951.3 EPE36428.1 - 8.4e-06 24.6 1.3 1.2e-05 24.0 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF239 PF03080.10 EPE36429.1 - 4e-30 104.5 3.6 8e-30 103.6 2.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF239) TPR_12 PF13424.1 EPE36432.1 - 4e-29 100.3 12.3 1.1e-09 38.0 0.0 5.8 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 EPE36432.1 - 2e-26 91.0 2.8 8.3e-05 22.3 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat HET PF06985.6 EPE36432.1 - 3.6e-23 82.2 7.2 1.1e-21 77.4 3.3 3.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.17 EPE36432.1 - 5.7e-11 41.8 0.0 1.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EPE36432.1 - 2.8e-06 27.0 0.0 5.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_11 PF13414.1 EPE36432.1 - 3.8e-06 26.4 10.5 0.11 12.1 0.0 5.4 5 1 0 6 6 6 2 TPR repeat TPR_7 PF13176.1 EPE36432.1 - 7e-06 25.4 2.0 0.0071 16.0 0.3 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPE36432.1 - 1.4e-05 24.6 13.0 0.033 14.1 1.4 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPE36432.1 - 4.1e-05 24.1 3.6 6.2 7.6 0.1 5.7 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EPE36432.1 - 8.9e-05 22.5 0.2 0.26 11.8 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 EPE36432.1 - 0.00019 21.5 0.0 0.00057 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.23 EPE36432.1 - 0.00031 20.2 8.6 0.035 13.7 0.7 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPE36432.1 - 0.0036 17.8 4.4 7.2 7.5 0.0 5.6 6 1 1 7 7 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 EPE36432.1 - 0.0085 15.5 1.9 0.09 12.2 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_19 PF14559.1 EPE36432.1 - 0.063 13.6 3.4 11 6.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPE36432.1 - 0.9 10.1 4.6 1.5 9.4 0.2 3.8 4 0 0 4 4 2 0 Tetratricopeptide repeat adh_short PF00106.20 EPE36433.1 - 5.9e-18 65.3 2.7 5.9e-18 65.3 1.8 2.3 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE36433.1 - 2.1e-14 53.8 2.0 3.1e-12 46.7 1.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE36433.1 - 4.9e-08 32.8 1.0 1.3e-07 31.4 0.1 1.8 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.13 EPE36433.1 - 0.0059 16.5 0.3 0.011 15.7 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain DUF1776 PF08643.5 EPE36433.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glycogen_syn PF05693.8 EPE36433.1 - 0.015 13.5 0.0 0.023 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase 3Beta_HSD PF01073.14 EPE36433.1 - 0.017 13.8 0.1 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EPE36433.1 - 0.023 14.7 0.4 0.05 13.6 0.3 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EPE36433.1 - 0.044 12.6 0.1 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EPE36433.1 - 0.06 12.7 0.2 0.23 10.8 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.20 EPE36434.1 - 1.8e-31 109.2 0.0 3.3e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE36434.1 - 8e-09 34.9 0.0 1.4e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPE36434.1 - 0.00046 20.0 4.4 0.0009 19.0 0.3 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family zf-RING_2 PF13639.1 EPE36436.1 - 5e-08 32.6 7.0 5e-08 32.6 4.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPE36436.1 - 0.00033 20.2 4.0 0.00099 18.7 2.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE36436.1 - 0.00048 20.0 7.3 0.0054 16.7 5.0 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE36436.1 - 0.00087 18.9 4.8 0.0024 17.5 3.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EPE36436.1 - 0.0024 17.9 1.1 0.0057 16.7 0.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EPE36436.1 - 0.0041 16.8 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EPE36436.1 - 0.0045 16.8 1.2 0.016 15.0 0.8 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-like PF04071.7 EPE36436.1 - 0.014 15.1 0.2 0.032 13.9 0.2 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain zf-C3HC4 PF00097.20 EPE36436.1 - 0.03 14.0 3.0 0.098 12.3 2.1 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EGF_3 PF12947.2 EPE36436.1 - 0.23 11.4 0.2 0.23 11.4 0.2 2.2 2 0 0 2 2 2 0 EGF domain zf-RING_2 PF13639.1 EPE36437.1 - 1.6e-08 34.2 7.0 3.2e-08 33.2 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPE36437.1 - 7.7e-05 22.3 6.2 0.00016 21.2 4.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPE36437.1 - 0.00029 20.4 3.9 0.00062 19.3 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPE36437.1 - 0.00033 20.3 1.9 0.00076 19.1 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EPE36437.1 - 0.00036 20.4 8.4 0.012 15.6 5.8 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPE36437.1 - 0.0016 18.0 2.6 0.004 16.7 1.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPE36437.1 - 0.0021 18.1 1.9 0.0043 17.1 1.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EPE36437.1 - 0.0023 17.7 2.2 0.0023 17.7 1.5 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 EPE36437.1 - 0.018 14.2 0.2 0.038 13.2 0.2 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_4 PF14570.1 EPE36437.1 - 0.95 9.0 8.2 0.074 12.6 2.0 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Tmemb_cc2 PF10267.4 EPE36440.1 - 0.59 8.6 1.8 0.73 8.3 1.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF605 PF04652.11 EPE36440.1 - 8.7 5.6 13.8 11 5.3 9.6 1.3 1 0 0 1 1 1 0 Vta1 like SAP PF02037.22 EPE36441.1 - 0.0054 16.2 4.5 0.13 11.7 0.0 4.5 5 0 0 5 5 5 1 SAP domain DUF1100 PF06500.6 EPE36442.1 - 6.2e-10 38.2 0.0 8e-10 37.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 EPE36442.1 - 1.2e-07 31.6 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE36442.1 - 1.4e-07 31.6 0.3 3.7e-07 30.2 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EPE36442.1 - 0.00017 21.0 0.1 0.0003 20.3 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EPE36442.1 - 0.0019 17.4 0.2 0.0049 16.1 0.1 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EPE36442.1 - 0.068 12.5 0.0 0.36 10.1 0.0 2.0 1 1 0 1 1 1 0 Putative esterase ZZ PF00569.12 EPE36443.1 - 1.4e-06 27.6 0.2 2.3e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Tmemb_14 PF03647.8 EPE36444.1 - 0.65 10.4 3.2 0.58 10.5 0.5 2.0 2 0 0 2 2 2 0 Transmembrane proteins 14C dCMP_cyt_deam_1 PF00383.17 EPE36447.1 - 0.0041 16.7 0.1 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SAP PF02037.22 EPE36449.1 - 1.7e-11 43.2 22.4 0.00048 19.5 0.2 8.1 8 0 0 8 8 8 3 SAP domain HeH PF12949.2 EPE36449.1 - 4.3e-05 22.9 0.2 0.00027 20.4 0.0 2.6 2 0 0 2 2 2 1 HeH/LEM domain YwpF PF14183.1 EPE36449.1 - 0.0052 16.4 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 YwpF-like protein DUF3541 PF12060.3 EPE36449.1 - 0.04 13.2 1.0 0.42 9.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) DUF1133 PF06576.6 EPE36449.1 - 0.054 12.6 0.1 12 5.0 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1133) LmjF365940-deam PF14421.1 EPE36449.1 - 0.086 12.2 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Armet PF10208.4 EPE36449.1 - 0.3 10.7 5.0 11 5.6 0.6 3.3 4 0 0 4 4 4 0 Degradation arginine-rich protein for mis-folding Pkinase PF00069.20 EPE36450.1 - 4.7e-25 88.2 0.0 9.5e-25 87.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE36450.1 - 3e-10 39.5 0.0 8.2e-10 38.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EPE36450.1 - 0.0063 15.5 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPE36450.1 - 0.024 14.3 0.2 0.12 12.0 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EPE36450.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like adh_short PF00106.20 EPE36451.1 - 4.8e-13 49.3 0.0 1.1e-12 48.1 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPE36451.1 - 1.1e-07 31.7 0.0 2.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE36451.1 - 0.00094 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4188 PF13826.1 EPE36452.1 - 1.8e-23 82.8 0.0 2.5e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EPE36452.1 - 0.019 14.0 0.1 0.025 13.6 0.1 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase DUF2973 PF11189.3 EPE36452.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Carb_anhydrase PF00194.16 EPE36454.1 - 2.6e-28 98.7 0.1 4.1e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RRM_1 PF00076.17 EPE36456.1 - 6.8e-20 70.4 0.0 2.3e-12 46.3 0.0 3.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE36456.1 - 6.8e-16 58.0 0.0 7.5e-09 35.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE36456.1 - 6.9e-12 45.0 0.0 4.6e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAA PF00277.13 EPE36456.1 - 0.079 13.3 0.4 0.079 13.3 0.3 1.7 2 0 0 2 2 2 0 Serum amyloid A protein Helicase_C PF00271.26 EPE36457.1 - 2.8e-19 68.7 0.0 1.2e-16 60.2 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EPE36457.1 - 1.5e-17 63.5 0.0 3.5e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EPE36457.1 - 0.00023 20.0 0.0 0.00046 19.0 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_4 PF13871.1 EPE36457.1 - 0.036 13.5 0.0 0.59 9.5 0.0 2.2 2 0 0 2 2 2 0 Helicase_C-like Peptidase_S41 PF03572.13 EPE36458.1 - 2.8e-06 26.8 0.0 1.1e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 DUF1515 PF07439.6 EPE36459.1 - 0.063 13.0 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) FlxA PF14282.1 EPE36460.1 - 0.1 12.5 4.6 0.19 11.6 3.2 1.5 1 1 0 1 1 1 0 FlxA-like protein DivIC PF04977.10 EPE36460.1 - 0.39 10.2 5.6 0.73 9.3 3.9 1.4 1 0 0 1 1 1 0 Septum formation initiator Vfa1 PF08432.5 EPE36460.1 - 1 9.3 6.5 1.2 9.0 4.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ACC_epsilon PF13822.1 EPE36460.1 - 1.9 8.9 6.7 3.2 8.1 4.7 1.4 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit DASH_Spc34 PF08657.5 EPE36460.1 - 2.1 7.9 7.8 2.5 7.7 5.4 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 AAA_13 PF13166.1 EPE36460.1 - 3.7 5.9 6.8 3.9 5.8 4.7 1.0 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EPE36460.1 - 5.6 5.9 5.9 7 5.6 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF612 PF04747.7 EPE36460.1 - 5.6 5.7 12.4 6.3 5.5 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Borrelia_P83 PF05262.6 EPE36460.1 - 6.8 4.8 10.4 7.4 4.7 7.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein p450 PF00067.17 EPE36461.1 - 6.1e-70 236.0 0.0 7.2e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.17 EPE36462.1 - 2.2e-41 139.3 0.0 1.1e-19 69.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE36462.1 - 2e-29 101.3 0.0 3.7e-14 52.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE36462.1 - 1.5e-19 69.5 0.0 2.2e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPE36462.1 - 0.00047 19.8 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif NDUFB10 PF10249.4 EPE36463.1 - 0.0014 18.8 0.0 0.0016 18.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 EPE36463.1 - 0.089 13.2 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 HWE histidine kinase Ribosomal_L37 PF08561.5 EPE36464.1 - 2.3e-24 84.7 0.4 3.2e-18 65.0 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 DUF2011 PF09428.5 EPE36464.1 - 0.18 11.6 3.6 0.34 10.8 2.5 1.4 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) TAFII55_N PF04658.8 EPE36465.1 - 2.8e-48 163.4 0.0 5.4e-48 162.5 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region Bromo_TP PF07524.8 EPE36466.1 - 6.8e-09 35.3 0.0 1.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EPE36466.1 - 0.0038 17.0 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TFIID_30kDa PF03540.8 EPE36466.1 - 0.044 13.6 0.1 0.079 12.7 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit ACT_6 PF13740.1 EPE36466.1 - 0.08 12.6 0.3 0.17 11.5 0.1 1.6 2 0 0 2 2 2 0 ACT domain BRO1 PF03097.13 EPE36468.1 - 0.00069 18.4 0.0 0.0015 17.4 0.0 1.6 2 0 0 2 2 2 1 BRO1-like domain Herpes_pp38 PF04846.8 EPE36469.1 - 0.087 12.1 0.2 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Fungal_trans_2 PF11951.3 EPE36470.1 - 9.1e-06 24.5 0.0 1.7e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 EPE36471.1 - 6e-21 74.7 0.0 7.6e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EPE36471.1 - 0.0037 17.5 0.0 0.0062 16.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F-box-like PF12937.2 EPE36472.1 - 0.19 11.5 0.1 0.19 11.5 0.1 2.0 2 0 0 2 2 2 0 F-box-like Pkinase PF00069.20 EPE36474.1 - 3.5e-20 72.2 0.0 1.2e-19 70.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE36474.1 - 8.9e-05 21.6 0.0 0.2 10.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2153 PF09921.4 EPE36474.1 - 0.0065 16.0 1.4 1.1 8.8 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2153) MBOAT_2 PF13813.1 EPE36475.1 - 0.0073 16.3 3.0 0.045 13.8 0.4 2.7 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Fungal_trans_2 PF11951.3 EPE36475.1 - 0.017 13.7 0.3 0.026 13.1 0.2 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE36475.1 - 0.034 14.0 5.4 0.077 12.9 3.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tannase PF07519.6 EPE36476.1 - 1.3e-78 264.8 0.0 2.2e-78 264.0 0.0 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EPE36476.1 - 0.00017 21.1 0.0 0.00053 19.6 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE36476.1 - 0.00029 20.7 0.0 0.00086 19.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family 3-PAP PF12578.3 EPE36478.1 - 0.045 13.6 0.2 4.1 7.2 0.0 2.2 1 1 1 2 2 2 0 Myotubularin-associated protein p450 PF00067.17 EPE36480.1 - 2.1e-29 102.3 0.0 2.6e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyltransferase PF01553.16 EPE36481.1 - 4.2e-21 74.7 0.0 6.1e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF2235 PF09994.4 EPE36482.1 - 3.1e-71 239.9 0.1 4.2e-71 239.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.6 EPE36482.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 EPE36482.1 - 0.087 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family An_peroxidase PF03098.10 EPE36483.1 - 1.2e-67 228.4 0.0 3e-65 220.6 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EPE36483.1 - 3.9e-08 32.2 0.1 3.4e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 HsbA PF12296.3 EPE36484.1 - 2.1e-19 69.6 1.1 2.5e-19 69.3 0.8 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A LPP PF04728.8 EPE36484.1 - 0.0044 16.7 0.1 0.0084 15.8 0.1 1.4 1 0 0 1 1 1 1 Lipoprotein leucine-zipper HSP90 PF00183.13 EPE36484.1 - 0.18 10.1 0.0 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Hsp90 protein Nuc_deoxyrib_tr PF05014.10 EPE36485.1 - 2e-26 92.0 0.0 2.5e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Pro-kuma_activ PF09286.6 EPE36486.1 - 1.5e-32 112.5 0.0 1.4e-28 99.6 0.0 2.2 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EPE36486.1 - 7.2e-14 51.5 0.1 7e-13 48.3 0.0 2.1 2 0 0 2 2 2 1 Subtilase family Mago-bind PF09282.5 EPE36486.1 - 0.051 13.1 0.3 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 Mago binding Cytochrom_B561 PF03188.11 EPE36487.1 - 7.8e-12 45.2 11.5 1.6e-11 44.2 8.0 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EPE36487.1 - 1e-06 28.6 0.0 2e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 EPE36487.1 - 0.00013 21.5 3.7 0.00013 21.5 2.5 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF2427) DUF4079 PF13301.1 EPE36487.1 - 0.51 10.3 11.0 31 4.5 0.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Alpha_GJ PF03229.8 EPE36487.1 - 1.5 9.1 10.7 0.55 10.5 4.6 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF4662 PF15578.1 EPE36488.1 - 0.069 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) HET PF06985.6 EPE36489.1 - 4.1e-22 78.8 0.0 8.4e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DPBB_1 PF03330.13 EPE36490.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Borrelia_P83 PF05262.6 EPE36490.1 - 0.0025 16.1 16.8 0.0031 15.8 11.7 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Daxx PF03344.10 EPE36490.1 - 0.022 13.2 34.1 0.03 12.8 23.6 1.2 1 0 0 1 1 1 0 Daxx Family Mitofilin PF09731.4 EPE36490.1 - 1.9 7.0 28.4 2.6 6.6 19.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pkinase PF00069.20 EPE36491.1 - 2.4e-65 220.2 0.0 3.3e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE36491.1 - 1.2e-31 109.7 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPE36491.1 - 0.018 14.0 0.0 0.042 12.8 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Pkinase_C PF00433.19 EPE36491.1 - 0.021 15.3 1.6 0.03 14.8 0.1 2.1 2 0 0 2 2 2 0 Protein kinase C terminal domain APH PF01636.18 EPE36491.1 - 0.065 12.9 0.3 0.8 9.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4246 PF14033.1 EPE36492.1 - 2e-132 442.3 0.2 2.5e-132 442.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Chordopox_A13L PF05961.6 EPE36492.1 - 0.056 13.3 0.1 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein HET PF06985.6 EPE36495.1 - 5.2e-26 91.4 0.0 1.3e-25 90.2 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.18 EPE36496.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family WSC PF01822.14 EPE36497.1 - 1.6e-16 59.9 8.3 1.6e-16 59.9 5.8 1.8 2 0 0 2 2 2 1 WSC domain zf-C2H2 PF00096.21 EPE36498.1 - 1.3e-11 44.1 52.3 0.07 13.5 1.6 8.2 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE36498.1 - 3.9e-09 36.1 55.3 0.043 14.1 1.0 8.3 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EPE36498.1 - 2.8e-05 24.1 35.8 0.061 13.4 0.5 6.5 2 1 4 6 6 6 3 C2H2 type zinc-finger (2 copies) Elf1 PF05129.8 EPE36498.1 - 0.00014 21.4 0.5 0.00014 21.4 0.4 5.0 4 2 2 6 6 6 2 Transcription elongation factor Elf1 like zf-H2C2_5 PF13909.1 EPE36498.1 - 0.0032 17.6 2.0 0.0032 17.6 1.4 7.7 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EPE36498.1 - 0.0063 16.6 43.3 0.19 11.9 0.2 7.7 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EPE36498.1 - 0.016 15.3 40.7 0.026 14.6 1.9 6.3 2 1 3 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EPE36498.1 - 0.02 14.8 0.4 0.02 14.8 0.2 6.4 8 0 0 8 8 8 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE36498.1 - 0.68 10.3 38.6 8 6.9 1.2 8.9 9 0 0 9 9 9 0 Zinc-finger double domain Methyltransf_31 PF13847.1 EPE36499.1 - 2.8e-12 46.4 0.1 4.3e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPE36499.1 - 5.1e-11 42.2 0.0 7.1e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EPE36499.1 - 5.3e-09 36.6 0.0 9.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE36499.1 - 1.4e-08 34.7 0.0 3.5e-08 33.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE36499.1 - 7.8e-08 32.7 0.0 1.5e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EPE36499.1 - 6.8e-07 28.5 0.0 9.7e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 EPE36499.1 - 1.9e-06 26.7 0.1 2.7e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 EPE36499.1 - 2.3e-06 27.4 0.0 3.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPE36499.1 - 1.8e-05 24.9 0.0 3.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPE36499.1 - 3.7e-05 23.1 0.1 6e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EPE36499.1 - 4.2e-05 22.7 0.0 5.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EPE36499.1 - 0.00023 21.1 0.1 0.00031 20.8 0.1 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 EPE36499.1 - 0.00092 19.6 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EPE36499.1 - 0.0046 16.4 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 EPE36499.1 - 0.014 14.5 0.6 0.071 12.2 0.0 2.3 2 1 1 3 3 3 0 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 EPE36499.1 - 0.033 13.3 0.8 0.091 11.8 0.2 2.0 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.10 EPE36499.1 - 0.035 13.4 0.0 0.071 12.4 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical protein 95 PCMT PF01135.14 EPE36499.1 - 0.035 13.6 0.1 0.059 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EPE36499.1 - 0.041 13.5 0.0 0.06 13.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EPE36499.1 - 0.073 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltrans_SAM PF10672.4 EPE36499.1 - 0.074 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase TFIIB PF00382.14 EPE36500.1 - 1e-22 79.7 0.1 5.2e-18 64.6 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EPE36500.1 - 1.3e-17 63.7 13.9 1.6e-17 63.5 2.0 3.6 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EPE36500.1 - 0.0098 15.2 0.7 0.03 13.6 0.5 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EPE36500.1 - 0.01 15.3 0.4 0.029 13.9 0.0 1.9 2 0 0 2 2 2 0 Cyclin, N-terminal domain Fer4_19 PF06902.6 EPE36502.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster KxDL PF10241.4 EPE36502.1 - 0.075 12.9 0.9 0.16 11.9 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein BCS1_N PF08740.6 EPE36503.1 - 6.2e-42 143.3 0.1 9.1e-42 142.7 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EPE36503.1 - 1e-16 61.3 0.0 1.9e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EPE36503.1 - 5.7e-05 22.6 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPE36503.1 - 0.00013 22.7 0.0 0.00044 21.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPE36503.1 - 0.00029 20.8 0.2 0.014 15.3 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EPE36503.1 - 0.002 18.2 0.0 0.015 15.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 EPE36503.1 - 0.003 16.5 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EPE36503.1 - 0.0044 16.8 0.0 0.0094 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPE36503.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 EPE36503.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPE36503.1 - 0.024 14.9 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EPE36503.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 EPE36503.1 - 0.026 13.5 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EPE36503.1 - 0.032 14.4 0.0 0.075 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EPE36503.1 - 0.047 13.2 0.1 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EPE36503.1 - 0.052 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PPV_E1_C PF00519.12 EPE36503.1 - 0.058 11.9 0.0 0.088 11.4 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_28 PF13521.1 EPE36503.1 - 0.073 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPE36503.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EPE36503.1 - 0.082 13.4 0.0 0.29 11.6 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein KaiC PF06745.8 EPE36503.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EPE36503.1 - 0.15 11.7 0.0 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EPE36503.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 2 0 0 2 2 1 0 Archaeal ATPase CHZ PF09649.5 EPE36504.1 - 1.5e-07 30.5 0.2 3.1e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 Histone chaperone domain CHZ Yqai PF09466.5 EPE36504.1 - 0.067 13.2 0.1 0.096 12.7 0.1 1.3 1 0 0 1 1 1 0 Hypothetical protein Yqai Grp1_Fun34_YaaH PF01184.14 EPE36505.1 - 2.8e-19 69.2 17.8 3.7e-19 68.8 12.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Glyoxalase_2 PF12681.2 EPE36506.1 - 1.5e-12 48.1 0.0 4.9e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EPE36506.1 - 3.3e-11 43.2 0.0 5.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EPE36506.1 - 1e-06 28.7 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EPE36506.1 - 0.089 12.6 0.2 1.4 8.8 0.2 2.2 1 1 0 1 1 1 0 Glyoxalase-like domain Glyco_hydro_2_N PF02837.13 EPE36507.1 - 3.4e-26 91.7 0.1 6e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EPE36507.1 - 3e-12 46.0 0.0 5.1e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EPE36507.1 - 4.6e-08 33.4 0.0 9.5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EPE36507.1 - 0.00021 21.5 0.3 0.00055 20.1 0.2 1.7 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain IBR PF01485.16 EPE36508.1 - 4.3e-15 55.3 19.4 4.2e-10 39.3 7.3 4.5 3 1 2 5 5 5 2 IBR domain DUF3337 PF11816.3 EPE36508.1 - 0.026 13.9 1.1 0.042 13.2 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) RibD_C PF01872.12 EPE36509.1 - 6.5e-32 110.7 0.0 7.5e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Bac_luciferase PF00296.15 EPE36510.1 - 1e-46 159.5 0.0 1.5e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF493 PF04359.9 EPE36510.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF493) DUF2358 PF10184.4 EPE36513.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) RicinB_lectin_2 PF14200.1 EPE36514.1 - 0.0033 17.7 0.4 0.01 16.2 0.2 1.8 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Herpes_gE PF02480.11 EPE36514.1 - 0.012 13.9 0.0 0.016 13.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E AF-4 PF05110.8 EPE36514.1 - 1.9 6.2 12.8 2.5 5.8 8.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Lamp PF01299.12 EPE36514.1 - 7.4 5.6 6.9 8.9 5.3 2.8 2.0 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) HET PF06985.6 EPE36515.1 - 5.4e-21 75.2 0.0 9.2e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EPE36517.1 - 3.2e-34 118.2 33.3 3.2e-34 118.2 23.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE36517.1 - 4.3e-07 28.8 29.3 2.6e-06 26.3 20.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter ERCC4 PF02732.10 EPE36518.1 - 3.1e-31 108.0 0.1 5.2e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EPE36518.1 - 0.00013 22.1 0.0 0.00045 20.3 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain PGM_PMM_I PF02878.11 EPE36519.1 - 1.5e-19 69.8 0.0 9.4e-10 38.1 0.0 2.9 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 EPE36519.1 - 2.1e-13 50.0 0.3 5.5e-13 48.7 0.2 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 EPE36519.1 - 8.7e-12 45.2 1.2 9.4e-11 41.9 0.3 3.0 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EPE36519.1 - 0.00088 19.3 0.1 0.0023 17.9 0.1 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Dicty_REP PF05086.7 EPE36520.1 - 0.68 7.6 12.0 0.96 7.1 8.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LRR_4 PF12799.2 EPE36521.1 - 0.13 11.8 0.7 86 2.9 0.0 4.6 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPE36521.1 - 0.14 11.8 2.5 59 3.5 0.0 4.4 4 1 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 EPE36523.1 - 0.016 14.8 0.2 20 4.9 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) DIOX_N PF14226.1 EPE36525.1 - 2.2e-19 70.0 0.1 4.5e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPE36525.1 - 1.6e-10 41.1 0.0 3.3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3650 PF12368.3 EPE36525.1 - 0.021 14.3 0.1 0.081 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) MFS_1 PF07690.11 EPE36526.1 - 2.8e-23 82.1 31.2 2.8e-23 82.1 21.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Asp_Glu_race PF01177.17 EPE36527.1 - 2.2e-17 63.6 0.0 2.6e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase FAD_binding_3 PF01494.14 EPE36528.1 - 1.7e-17 63.5 0.2 7.4e-17 61.4 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EPE36528.1 - 4.8e-05 22.6 0.1 0.0052 15.9 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPE36528.1 - 9.1e-05 22.4 0.2 0.00024 21.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE36528.1 - 0.00024 20.1 3.6 0.051 12.4 2.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPE36528.1 - 0.00075 19.2 0.9 0.89 9.3 0.4 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPE36528.1 - 0.0027 17.6 0.4 0.0053 16.6 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE36528.1 - 0.0098 14.7 1.3 0.015 14.1 0.6 1.5 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.12 EPE36528.1 - 0.038 13.0 0.1 0.083 11.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EPE36528.1 - 0.13 12.6 1.4 1.3 9.4 0.2 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE36528.1 - 0.29 10.0 1.3 2.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Fungal_trans PF04082.13 EPE36529.1 - 2.6e-23 82.2 1.7 7e-23 80.8 1.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE36529.1 - 0.0015 18.3 14.8 0.0032 17.3 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 EPE36530.1 - 1.9e-60 204.5 0.0 2.6e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPE36530.1 - 6.1e-30 104.4 0.0 1.2e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPE36530.1 - 9.4e-07 28.0 0.0 0.015 14.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE36530.1 - 0.0011 18.9 0.2 0.0028 17.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE36530.1 - 0.0026 16.7 0.2 0.0041 16.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPE36530.1 - 0.0082 16.2 0.0 5.5 7.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE36530.1 - 0.014 15.3 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPE36530.1 - 0.05 12.4 0.2 1.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EPE36530.1 - 0.056 11.9 0.1 0.27 9.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EPE36530.1 - 0.08 11.7 0.4 0.15 10.8 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Transp_cyt_pur PF02133.10 EPE36531.1 - 3.5e-77 259.8 39.0 4e-77 259.6 27.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HET PF06985.6 EPE36532.1 - 4.3e-28 98.2 0.0 9.5e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EPE36533.1 - 1.3e-34 119.2 0.9 2.3e-34 118.5 0.3 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Aminoglyc_resit PF10706.4 EPE36533.1 - 0.049 13.2 0.2 0.7 9.4 0.0 2.5 3 0 0 3 3 3 0 Aminoglycoside-2''-adenylyltransferase Aldedh PF00171.17 EPE36534.1 - 7.7e-153 509.1 0.3 8.6e-153 508.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPE36534.1 - 0.0038 16.0 0.0 0.0057 15.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EPE36534.1 - 0.0088 15.2 0.0 0.055 12.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Acetyltransf_3 PF13302.1 EPE36536.1 - 1.3e-16 61.0 0.1 1.9e-16 60.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE36536.1 - 2.9e-07 30.4 0.1 6e-07 29.3 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EPE36536.1 - 0.0066 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPE36536.1 - 0.075 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain YppF PF14178.1 EPE36536.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 YppF-like protein EHN PF06441.7 EPE36539.1 - 8.4e-34 115.8 0.1 1.4e-33 115.1 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EPE36539.1 - 3.9e-09 36.7 0.2 2e-08 34.3 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE36539.1 - 1.1e-05 25.0 0.1 0.00011 21.8 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Transp_cyt_pur PF02133.10 EPE36540.1 - 2.8e-31 108.5 27.8 3.9e-31 108.0 19.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FAD_binding_3 PF01494.14 EPE36542.1 - 1.4e-12 47.3 1.7 1.3e-09 37.5 1.4 3.0 2 1 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EPE36542.1 - 0.00012 22.4 0.1 0.00025 21.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE36542.1 - 0.00016 20.6 0.2 0.0022 16.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE36542.1 - 0.0023 17.9 0.2 0.0047 16.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EPE36542.1 - 0.0036 15.8 0.1 0.0065 14.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EPE36542.1 - 0.059 12.2 2.5 0.043 12.6 0.5 1.6 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 EPE36542.1 - 0.14 10.7 0.1 4.8 5.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.1 EPE36542.1 - 0.18 10.6 0.0 1.1 8.1 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_4 PF07993.7 EPE36543.1 - 1.1e-22 80.1 0.0 1.9e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EPE36543.1 - 1.8e-07 30.8 0.0 2.8e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.23 EPE36543.1 - 0.00055 18.4 0.0 0.053 11.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme BTB PF00651.26 EPE36544.1 - 3.5e-07 30.1 0.0 9.2e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Lactamase_B PF00753.22 EPE36545.1 - 2.1e-08 34.0 0.2 3.3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPE36545.1 - 0.0014 18.2 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain F-box-like PF12937.2 EPE36546.1 - 0.012 15.2 0.3 0.062 13.0 0.1 2.2 2 0 0 2 2 2 0 F-box-like Gly_transf_sug PF04488.10 EPE36547.1 - 4.9e-10 39.7 0.1 1.3e-09 38.3 0.1 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EPE36547.1 - 0.0092 15.1 0.6 0.024 13.8 0.4 1.7 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Acyl_transf_3 PF01757.17 EPE36548.1 - 1.8e-33 115.7 38.1 2.3e-33 115.4 26.4 1.1 1 0 0 1 1 1 1 Acyltransferase family TPR_11 PF13414.1 EPE36550.1 - 6e-08 32.2 3.3 0.035 13.7 0.1 4.7 4 0 0 4 4 4 2 TPR repeat TPR_9 PF13371.1 EPE36550.1 - 0.023 14.5 2.2 0.083 12.7 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPE36550.1 - 0.12 12.6 1.1 7.3 7.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPE36550.1 - 0.2 11.9 7.3 5.7 7.3 1.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPE36550.1 - 3.5 7.7 5.8 9.9 6.3 0.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 EPE36551.1 - 3.3e-157 523.3 0.0 4.1e-157 522.9 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 EPE36551.1 - 3.5e-06 27.1 0.2 2.7 8.8 0.0 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPE36551.1 - 3.4e-05 23.4 0.0 0.46 10.1 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 EPE36551.1 - 9.1e-05 22.7 0.0 0.045 14.0 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPE36551.1 - 0.00055 19.7 0.1 0.07 12.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPE36551.1 - 0.0012 18.4 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPE36551.1 - 0.0013 18.4 0.1 0.47 10.5 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPE36551.1 - 0.057 13.2 0.1 0.72 9.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Nup160 PF11715.3 EPE36552.1 - 0.017 13.3 0.0 0.023 12.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 TMEM171 PF15471.1 EPE36552.1 - 0.21 10.3 1.4 0.32 9.7 1.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 HET PF06985.6 EPE36553.1 - 0.017 15.2 1.7 0.041 14.0 1.2 1.6 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DBI_PRT PF02277.12 EPE36553.1 - 0.037 13.1 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase DUF3353 PF11833.3 EPE36553.1 - 0.11 11.9 0.2 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Glyco_hydro_72 PF03198.9 EPE36554.1 - 5.8e-102 340.8 0.0 7.2e-102 340.5 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_3 PF00933.16 EPE36556.1 - 1.7e-58 198.0 0.0 2.3e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE36556.1 - 1.2e-38 132.9 0.1 1.9e-38 132.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Epimerase_Csub PF13950.1 EPE36556.1 - 0.099 12.5 1.0 0.34 10.8 0.2 2.3 2 0 0 2 2 2 0 UDP-glucose 4-epimerase C-term subunit Colicin_D PF11429.3 EPE36559.1 - 5.9e-18 64.8 0.0 8.8e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Colicin D TUDOR PF00567.19 EPE36560.1 - 0.032 14.0 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Tudor domain DUF605 PF04652.11 EPE36562.1 - 2.2 7.6 4.2 2.9 7.2 2.9 1.1 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 EPE36563.1 - 1.6e-52 178.2 0.1 2.7e-36 125.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE36563.1 - 3.2e-22 78.8 0.1 1.6e-11 43.7 0.0 2.8 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EPE36563.1 - 1.4e-06 27.5 0.0 2.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPE36563.1 - 0.0015 18.3 0.2 0.0055 16.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribonuc_red_lgC PF02867.10 EPE36564.1 - 5.6e-218 724.8 0.0 9.8e-218 724.0 0.0 1.4 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EPE36564.1 - 2.4e-23 81.7 0.1 5.8e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EPE36564.1 - 3.2e-16 59.5 0.1 9.2e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 ATP cone domain DGF-1_C PF11040.3 EPE36564.1 - 0.0098 15.7 0.1 0.031 14.1 0.1 1.8 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus HET PF06985.6 EPE36566.1 - 6e-18 65.3 0.1 3.8e-17 62.7 0.0 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) MMR_HSR1 PF01926.18 EPE36566.1 - 1.1e-07 31.7 0.0 8.7e-07 28.9 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EPE36566.1 - 2.7e-05 23.7 0.0 6.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EPE36566.1 - 0.00038 19.4 0.0 0.0008 18.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 EPE36566.1 - 0.00056 19.3 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AIG1 PF04548.11 EPE36566.1 - 0.00094 18.3 0.0 0.076 12.1 0.1 2.5 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 EPE36566.1 - 0.00094 18.3 0.0 0.0046 16.1 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EPE36566.1 - 0.0025 16.8 0.0 0.0058 15.6 0.0 1.5 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.18 EPE36566.1 - 0.0029 17.4 1.0 0.034 13.9 0.0 2.7 3 0 0 3 3 3 1 Dynamin family T2SE PF00437.15 EPE36566.1 - 0.003 16.5 0.0 0.0058 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 EPE36566.1 - 0.0044 17.3 4.6 0.017 15.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EPE36566.1 - 0.0061 16.8 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EPE36566.1 - 0.024 14.7 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EPE36566.1 - 0.03 13.7 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain Miro PF08477.8 EPE36566.1 - 0.039 14.4 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein DUF87 PF01935.12 EPE36566.1 - 0.05 13.4 0.1 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 EPE36566.1 - 0.062 13.4 0.1 0.44 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 EPE36566.1 - 0.065 14.0 0.1 0.36 11.6 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.1 EPE36566.1 - 0.07 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 EPE36566.1 - 0.083 12.3 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain MobB PF03205.9 EPE36566.1 - 0.087 12.5 0.0 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NMO PF03060.10 EPE36567.1 - 0.42 9.7 3.2 0.63 9.1 1.0 1.9 2 0 0 2 2 2 0 Nitronate monooxygenase 60KD_IMP PF02096.15 EPE36568.1 - 3.7e-25 88.7 0.1 4.7e-25 88.4 0.1 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Glycos_transf_1 PF00534.15 EPE36569.1 - 1.1e-22 80.3 0.0 1.6e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPE36569.1 - 4.4e-10 39.8 0.0 7.4e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF718 PF05336.8 EPE36569.1 - 0.061 13.1 0.6 9.7 6.0 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF718) Glyco_transf_4 PF13439.1 EPE36569.1 - 0.088 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DpnD-PcfM PF14207.1 EPE36569.1 - 0.11 12.2 2.2 0.76 9.5 2.3 1.7 2 0 0 2 2 2 0 DpnD/PcfM-like protein G_glu_transpept PF01019.16 EPE36570.1 - 5e-40 137.4 0.8 6.1e-40 137.1 0.5 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.16 EPE36571.1 - 6.7e-111 371.2 0.0 7.9e-111 371.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase COesterase PF00135.23 EPE36572.1 - 1.3e-86 291.4 0.0 1.6e-86 291.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPE36572.1 - 2e-07 30.8 0.0 1.6e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 EPE36574.1 - 8e-07 27.9 0.6 1.2e-06 27.3 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE36574.1 - 5e-05 23.1 10.9 9.2e-05 22.2 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 EPE36575.1 - 1.5e-51 172.6 13.6 4e-15 55.9 0.0 6.1 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EPE36575.1 - 9.3e-34 113.5 15.8 0.00011 21.7 0.0 12.0 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 EPE36575.1 - 2.8e-25 88.2 11.9 2.4e-06 27.9 0.0 8.8 7 2 3 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE36575.1 - 6.6e-19 66.1 17.0 0.022 14.9 0.0 10.9 11 0 0 11 11 9 4 Ankyrin repeat Ank_5 PF13857.1 EPE36575.1 - 3e-14 52.6 8.9 0.022 14.9 0.0 8.1 5 3 3 8 8 8 3 Ankyrin repeats (many copies) NACHT PF05729.7 EPE36575.1 - 6.5e-09 35.6 0.0 2.5e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPE36575.1 - 6.5e-06 26.2 0.1 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPE36575.1 - 6.3e-05 23.1 0.0 0.00052 20.1 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EPE36575.1 - 0.02 14.6 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 EPE36575.1 - 0.062 12.2 1.7 0.23 10.3 0.1 2.2 2 0 0 2 2 2 0 KAP family P-loop domain EppA_BapA PF07268.6 EPE36575.1 - 0.07 12.8 0.0 3.4 7.3 0.0 3.3 3 0 0 3 3 3 0 Exported protein precursor (EppA/BapA) Carn_acyltransf PF00755.15 EPE36576.1 - 8.8e-164 545.8 0.0 4.6e-149 497.2 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase DUF2486 PF10667.4 EPE36576.1 - 0.0081 16.7 0.6 0.018 15.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2486) CTD_bind PF04818.8 EPE36576.1 - 0.15 12.3 0.0 31 4.9 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase II-binding domain. SPT2 PF08243.6 EPE36577.1 - 4.3e-05 23.7 14.8 4.3e-05 23.7 10.3 2.8 1 1 1 2 2 2 1 SPT2 chromatin protein Glyco_hydro_cc PF11790.3 EPE36578.1 - 9.3e-60 202.0 0.1 1.3e-59 201.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core HET PF06985.6 EPE36579.1 - 0.00039 20.5 0.3 0.00076 19.6 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SopA PF13981.1 EPE36581.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 SopA-like central domain Chromo PF00385.19 EPE36582.1 - 5.1e-08 32.4 1.3 8.7e-08 31.7 0.9 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Methyltransf_11 PF08241.7 EPE36584.1 - 2.9e-10 40.4 0.0 5.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE36584.1 - 0.00053 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE36584.1 - 0.035 14.5 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EPE36584.1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EPE36584.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.9 EPE36586.1 - 1.4e-29 103.3 0.0 3.2e-29 102.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EPE36586.1 - 5e-20 71.5 0.0 1.2e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EPE36586.1 - 1e-16 61.1 1.5 6.9e-16 58.4 0.9 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE36586.1 - 3.2e-05 24.1 0.0 5.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE36586.1 - 0.00011 22.0 0.2 0.66 10.0 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.1 EPE36586.1 - 0.057 13.7 0.0 0.55 10.5 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain DAO PF01266.19 EPE36586.1 - 3.6 6.3 5.7 12 4.6 0.0 3.4 2 2 2 4 4 4 0 FAD dependent oxidoreductase HECT_2 PF09814.4 EPE36587.1 - 6.7e-59 199.3 0.8 8.7e-59 199.0 0.6 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.9 EPE36587.1 - 0.023 14.7 0.0 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FAD_binding_3 PF01494.14 EPE36588.1 - 8.9e-21 74.3 0.0 1.5e-09 37.3 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EPE36588.1 - 1.5e-06 28.1 0.0 3.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE36588.1 - 0.00011 21.2 0.0 0.00022 20.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPE36588.1 - 0.00016 21.6 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EPE36588.1 - 0.0016 17.5 0.1 0.029 13.4 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EPE36588.1 - 0.0016 18.4 0.0 0.0024 17.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPE36588.1 - 0.0018 18.6 0.0 0.005 17.2 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE36588.1 - 0.0037 16.2 0.1 0.11 11.3 0.0 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein ApbA PF02558.11 EPE36588.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EPE36588.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 EPE36588.1 - 0.024 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EPE36588.1 - 0.03 14.4 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EPE36588.1 - 0.033 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EPE36588.1 - 0.038 12.8 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain SE PF08491.5 EPE36588.1 - 0.045 12.5 0.0 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.12 EPE36588.1 - 0.052 12.6 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 EPE36588.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4243 PF14027.1 EPE36589.1 - 6.2e-85 285.5 0.1 7.8e-85 285.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Rad17 PF03215.10 EPE36590.1 - 7.6e-57 193.1 0.0 1.4e-56 192.2 0.0 1.3 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 EPE36590.1 - 0.03 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HET PF06985.6 EPE36591.1 - 1.5e-23 83.4 0.0 3e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C3HC4 PF00097.20 EPE36592.1 - 2.8e-12 46.0 8.7 4.6e-12 45.3 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPE36592.1 - 4.2e-12 45.6 8.9 6.6e-12 45.0 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPE36592.1 - 6e-12 45.3 9.2 8.8e-12 44.8 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPE36592.1 - 4.5e-10 39.0 4.8 6.4e-10 38.5 3.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE36592.1 - 4e-07 29.6 7.0 6.5e-07 28.9 4.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPE36592.1 - 9.7e-07 28.5 7.8 1.7e-06 27.7 5.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPE36592.1 - 2e-06 27.4 5.4 3.8e-06 26.5 3.4 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-Nse PF11789.3 EPE36592.1 - 2.8e-06 26.7 6.6 5e-06 25.9 4.6 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EPE36592.1 - 2.9e-05 24.1 7.3 0.00012 22.1 5.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPE36592.1 - 0.00042 20.0 3.8 0.001 18.8 2.6 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EPE36592.1 - 0.00095 18.6 7.2 0.0014 18.1 5.0 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EPE36592.1 - 0.066 13.0 2.3 0.14 11.9 1.6 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein BUD22 PF09073.5 EPE36592.1 - 0.11 11.5 8.9 0.12 11.4 6.2 1.1 1 0 0 1 1 1 0 BUD22 zf-RING_3 PF14369.1 EPE36592.1 - 0.31 11.0 6.0 7.7 6.6 0.5 2.7 2 0 0 2 2 2 0 zinc-finger DUF2457 PF10446.4 EPE36592.1 - 0.31 9.7 15.8 0.35 9.5 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 EPE36592.1 - 0.74 8.2 16.0 0.97 7.8 11.1 1.2 1 0 0 1 1 1 0 Daxx Family Baculo_IE-1 PF05290.6 EPE36592.1 - 0.81 9.4 4.5 1 9.0 2.7 1.4 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE PF01363.16 EPE36592.1 - 1.4 8.8 6.1 4.5 7.2 4.2 1.8 1 1 0 1 1 1 0 FYVE zinc finger Nop14 PF04147.7 EPE36592.1 - 1.4 6.7 15.4 1.4 6.7 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EPE36592.1 - 1.5 8.5 13.3 2 8.0 9.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-RING_4 PF14570.1 EPE36592.1 - 1.5 8.4 13.9 0.42 10.2 1.7 2.7 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain DUF1644 PF07800.7 EPE36592.1 - 3.1 7.6 11.2 0.35 10.7 1.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) Prok-RING_1 PF14446.1 EPE36592.1 - 3.3 7.5 9.0 1.3 8.8 3.4 2.2 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 CDC45 PF02724.9 EPE36592.1 - 4.7 5.1 13.5 5.3 4.9 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein FANCL_C PF11793.3 EPE36592.1 - 8 6.5 8.7 30 4.6 6.0 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain PPP4R2 PF09184.6 EPE36592.1 - 8 5.9 18.0 1.4 8.3 9.4 1.8 2 0 0 2 2 2 0 PPP4R2 Rad51 PF08423.6 EPE36593.1 - 6.5e-26 90.7 0.0 9.7e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EPE36593.1 - 5.8e-09 35.6 0.1 1.6e-08 34.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 EPE36593.1 - 1.6e-06 27.4 0.1 0.00016 20.8 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein KaiC PF06745.8 EPE36593.1 - 1.7e-05 24.0 0.0 4.8e-05 22.5 0.0 1.7 2 1 0 2 2 2 1 KaiC AAA_22 PF13401.1 EPE36593.1 - 0.027 14.6 0.0 0.085 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.10 EPE36593.1 - 0.029 13.2 0.1 0.1 11.4 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAN_1 PF00024.21 EPE36595.1 - 6.6e-05 22.5 0.3 0.00014 21.5 0.2 1.4 1 0 0 1 1 1 1 PAN domain Fringe PF02434.11 EPE36595.1 - 0.0087 15.3 0.8 0.12 11.6 0.5 2.1 1 1 0 1 1 1 1 Fringe-like PAN_3 PF08277.7 EPE36595.1 - 0.014 15.0 1.2 0.025 14.1 0.8 1.4 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.1 EPE36595.1 - 0.033 13.8 0.6 0.084 12.5 0.4 1.6 1 0 0 1 1 1 0 PAN domain zf-C2H2 PF00096.21 EPE36597.1 - 0.011 15.9 2.2 0.011 15.9 1.5 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE36597.1 - 1.8 9.0 20.9 0.38 11.1 0.9 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger adh_short PF00106.20 EPE36599.1 - 8.2e-13 48.6 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE36599.1 - 1.7e-05 24.6 0.0 2.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EPE36599.1 - 0.0023 17.1 0.0 0.02 14.0 0.0 1.9 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EPE36599.1 - 0.0078 15.8 0.1 0.96 9.0 0.0 2.2 2 0 0 2 2 2 2 KR domain DRMBL PF07522.9 EPE36600.1 - 3.5e-35 120.3 0.1 6.7e-35 119.4 0.1 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EPE36600.1 - 1.6e-12 47.3 0.0 3.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain LSM PF01423.17 EPE36601.1 - 2.2e-15 55.9 0.8 4.5e-15 54.9 0.6 1.5 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPE36601.1 - 0.0072 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 EPE36601.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SnoaL PF07366.7 EPE36602.1 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EPE36602.1 - 0.03 14.7 0.1 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain Ank_2 PF12796.2 EPE36603.1 - 5.4e-27 93.9 0.1 7.8e-14 51.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPE36603.1 - 1.1e-22 78.6 0.2 5.5e-06 25.9 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EPE36603.1 - 1e-18 66.8 0.3 1.2e-06 28.5 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPE36603.1 - 2.1e-18 66.2 0.1 2.9e-10 40.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE36603.1 - 1.2e-15 56.0 0.0 0.0042 17.1 0.0 5.4 6 0 0 6 6 5 3 Ankyrin repeat CorA PF01544.13 EPE36603.1 - 0.0013 17.8 8.9 0.0013 17.8 6.2 2.7 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein TRP PF06011.7 EPE36603.1 - 0.0038 15.8 2.6 0.0061 15.1 1.8 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF998 PF06197.8 EPE36603.1 - 0.12 11.6 8.8 0.19 11.0 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) FA_desaturase PF00487.19 EPE36603.1 - 0.81 9.0 0.8 1.5 8.1 0.5 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DUF418 PF04235.7 EPE36603.1 - 4 7.1 8.6 5.7 6.5 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) Yip1 PF04893.12 EPE36603.1 - 6.5 6.2 12.2 18 4.7 8.5 1.5 1 1 0 1 1 1 0 Yip1 domain Fig1 PF12351.3 EPE36604.1 - 1.4e-50 171.6 1.0 1.4e-50 171.6 0.7 1.9 1 1 2 3 3 3 1 Ca2+ regulator and membrane fusion protein Fig1 DUF3649 PF12365.3 EPE36604.1 - 2.2 7.8 5.9 1.3 8.5 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) NAD_binding_10 PF13460.1 EPE36605.1 - 1.4e-06 28.4 0.1 1.6e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPE36605.1 - 1e-05 24.3 0.1 1.4e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPE36605.1 - 0.00028 19.8 0.0 0.068 12.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein HET PF06985.6 EPE36608.1 - 1.1e-14 54.7 0.0 1.1e-13 51.4 0.0 2.7 3 1 0 3 3 3 1 Heterokaryon incompatibility protein (HET) zf-C2H2_4 PF13894.1 EPE36608.1 - 0.00017 21.7 13.9 0.94 9.9 0.5 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE36608.1 - 0.0088 16.2 10.8 0.14 12.4 0.3 4.1 4 0 0 4 4 4 1 Zinc-finger double domain DUF724 PF05266.9 EPE36608.1 - 0.017 14.7 7.2 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) zf-BED PF02892.10 EPE36608.1 - 0.048 13.4 3.0 4.2 7.2 0.3 2.6 2 0 0 2 2 2 0 BED zinc finger Myosin_HC-like PF07058.6 EPE36609.1 - 0.14 11.2 0.4 0.19 10.7 0.3 1.1 1 0 0 1 1 1 0 Myosin II heavy chain-like Peptidase_S8 PF00082.17 EPE36610.1 - 3.5e-08 32.9 0.5 7.1e-08 31.9 0.3 1.5 1 0 0 1 1 1 1 Subtilase family Ribosomal_S8e PF01201.17 EPE36611.1 - 2.7e-35 121.4 2.9 3.6e-31 108.0 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S8e DUF3433 PF11915.3 EPE36613.1 - 1e-31 108.8 14.1 2.8e-20 72.2 1.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Cytochrom_B_N PF00033.14 EPE36613.1 - 2.1 7.6 12.1 0.15 11.3 1.4 3.1 4 0 0 4 4 4 0 Cytochrome b(N-terminal)/b6/petB AA_permease PF00324.16 EPE36614.1 - 1e-96 324.1 49.9 1.3e-96 323.8 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE36614.1 - 5.4e-31 107.5 53.1 7.4e-31 107.1 36.8 1.2 1 0 0 1 1 1 1 Amino acid permease Synaptobrevin PF00957.16 EPE36614.1 - 1.2 8.8 0.0 1.2 8.8 0.0 4.2 6 0 0 6 6 6 0 Synaptobrevin RF-1 PF00472.15 EPE36615.1 - 0.036 13.8 0.1 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 RF-1 domain Interfer-bind PF09294.5 EPE36615.1 - 0.039 13.9 1.1 0.083 12.9 0.3 1.8 1 1 1 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Peptidase_M48 PF01435.13 EPE36616.1 - 2e-05 24.2 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 cwf21 PF08312.7 EPE36616.1 - 0.019 14.8 0.1 0.055 13.3 0.0 1.8 1 0 0 1 1 1 0 cwf21 domain Thaumatin PF00314.12 EPE36617.1 - 0.016 14.7 0.1 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Thaumatin family Asp PF00026.18 EPE36619.1 - 4.3e-12 45.8 0.0 7.9e-12 45.0 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.5 EPE36619.1 - 0.0073 15.6 0.3 0.014 14.6 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.6 EPE36619.1 - 0.0081 15.9 0.4 0.0081 15.9 0.3 2.2 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24) VSP PF03302.8 EPE36619.1 - 0.076 11.6 0.6 0.1 11.2 0.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4064 PF13273.1 EPE36619.1 - 0.084 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Pkinase PF00069.20 EPE36621.1 - 1.2e-44 152.4 0.0 1.9e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPE36621.1 - 3.8e-18 65.5 0.0 5.9e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EPE36621.1 - 0.0067 15.7 0.2 0.014 14.7 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EPE36621.1 - 0.021 13.7 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PsaA_PsaB PF00223.14 EPE36621.1 - 0.096 10.7 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Kdo PF06293.9 EPE36621.1 - 0.17 10.8 0.1 0.32 10.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipase_GDSL_2 PF13472.1 EPE36622.1 - 1e-13 51.8 0.0 1.2e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPE36622.1 - 9.9e-06 25.5 0.0 6.3e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PCI PF01399.22 EPE36623.1 - 5.2e-12 46.0 0.0 2.3e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EPE36623.1 - 6.7e-05 22.3 0.3 0.00017 21.0 0.2 1.7 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PI-PLC-X PF00388.14 EPE36624.1 - 1.8e-48 163.6 0.0 2.7e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EPE36624.1 - 3.4e-32 110.9 0.0 5.6e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EPE36624.1 - 0.0024 17.6 0.8 0.1 12.4 0.2 3.3 3 1 0 3 3 3 1 C2 domain TFIIF_beta PF02270.10 EPE36625.1 - 3e-75 253.5 0.8 3.6e-75 253.2 0.6 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit bPH_1 PF08000.6 EPE36625.1 - 0.076 12.6 0.2 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial PH domain zf-CCCH PF00642.19 EPE36626.1 - 2.8e-15 55.5 27.7 3.8e-07 29.6 0.4 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Beta-Casp PF10996.3 EPE36626.1 - 0.14 12.0 0.2 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 Beta-Casp domain bZIP_Maf PF03131.12 EPE36627.1 - 4e-07 30.2 11.7 4e-07 30.2 8.1 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EPE36627.1 - 5.2e-06 26.3 10.0 5.2e-06 26.3 7.0 2.5 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EPE36627.1 - 8.1e-06 25.5 9.5 8.1e-06 25.5 6.6 2.1 2 0 0 2 2 2 1 Basic region leucine zipper DUF148 PF02520.12 EPE36627.1 - 0.0053 16.5 3.6 0.0053 16.5 2.5 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF148 AAA_23 PF13476.1 EPE36627.1 - 0.042 14.1 5.0 0.079 13.2 3.4 1.5 1 0 0 1 1 1 0 AAA domain Sel1 PF08238.7 EPE36628.1 - 2.2e-20 72.5 7.2 1.2e-06 28.9 0.0 3.7 3 0 0 3 3 3 3 Sel1 repeat CBF PF03914.12 EPE36629.1 - 1.2e-48 164.6 0.1 4.8e-48 162.7 0.1 2.0 2 0 0 2 2 2 1 CBF/Mak21 family Talin_middle PF09141.5 EPE36629.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Talin, middle domain Mt_ATP-synt_B PF05405.9 EPE36630.1 - 1.6e-55 187.0 7.0 2.1e-55 186.6 4.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 EPE36630.1 - 0.064 13.1 0.8 0.11 12.3 0.6 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) GSH_synth_ATP PF03917.12 EPE36630.1 - 0.082 11.4 2.0 0.11 11.0 1.4 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain DUF3410 PF11890.3 EPE36631.1 - 0.052 13.2 0.4 0.14 11.8 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) DAO PF01266.19 EPE36633.1 - 1.4e-49 168.9 0.0 1.6e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPE36633.1 - 6.5e-08 32.8 0.3 9.6e-07 29.0 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE36633.1 - 1.6e-07 31.2 0.2 0.00014 21.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EPE36633.1 - 1.5e-05 24.9 0.1 4.1e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EPE36633.1 - 0.00012 20.7 0.2 0.0068 14.9 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.1 EPE36633.1 - 0.00072 18.5 0.0 0.38 9.6 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EPE36633.1 - 0.00086 18.4 0.0 0.002 17.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EPE36633.1 - 0.0042 16.9 1.7 0.1 12.4 0.2 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE36633.1 - 0.0083 15.0 0.3 0.2 10.4 0.0 2.6 2 1 1 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 EPE36633.1 - 0.012 16.0 1.2 4.8 7.6 0.0 3.1 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPE36633.1 - 0.035 13.0 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Effector_1 PF04518.7 EPE36633.1 - 0.16 10.9 1.2 0.25 10.2 0.8 1.2 1 0 0 1 1 1 0 Effector from type III secretion system Peptidase_M28 PF04389.12 EPE36634.1 - 3.9e-34 117.9 0.1 6.1e-34 117.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EPE36634.1 - 2.5e-08 33.5 1.7 2.8e-08 33.3 0.3 1.8 2 0 0 2 2 2 1 PA domain DUF1664 PF07889.7 EPE36635.1 - 3.2 7.5 6.0 1.5 8.6 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 EPE36635.1 - 6.2 4.5 6.2 10 3.7 4.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDE_3 PF13358.1 EPE36637.1 - 9.4e-20 70.8 1.6 1.1e-19 70.6 0.3 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EPE36637.1 - 1.2e-18 66.9 1.7 3e-18 65.6 0.5 2.0 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EPE36637.1 - 5.3e-07 29.7 0.0 1.8e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.21 EPE36637.1 - 0.00089 19.3 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HTH_24 PF13412.1 EPE36637.1 - 0.0082 15.5 0.0 0.02 14.2 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding KfrA_N PF11740.3 EPE36637.1 - 0.019 15.4 0.0 0.078 13.4 0.0 1.9 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term HTH_32 PF13565.1 EPE36637.1 - 0.1 13.3 2.3 0.33 11.7 0.2 2.7 3 0 0 3 3 3 0 Homeodomain-like domain HTH_21 PF13276.1 EPE36637.1 - 0.18 11.8 3.2 0.44 10.5 0.1 2.8 3 0 0 3 3 3 0 HTH-like domain Amidohydro_4 PF13147.1 EPE36639.1 - 3.9e-27 95.9 0.0 5.3e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EPE36639.1 - 9.1e-16 58.4 0.1 3.9e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EPE36639.1 - 6.2e-13 48.3 1.9 1.5e-12 47.1 0.9 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EPE36639.1 - 4e-11 42.7 0.0 1.4e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PTCRA PF15028.1 EPE36639.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Asp_Glu_race PF01177.17 EPE36640.1 - 2.4e-27 96.2 0.2 2.7e-27 96.0 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase CN_hydrolase PF00795.17 EPE36641.1 - 5.6e-25 87.7 0.0 2e-24 85.9 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.13 EPE36642.1 - 2.4e-25 88.8 0.4 3.3e-25 88.4 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE36642.1 - 0.00014 21.6 9.2 0.00031 20.5 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_tranf_2_4 PF13704.1 EPE36643.1 - 3.4e-09 36.8 0.5 6e-09 36.1 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 EPE36643.1 - 1.3e-07 31.2 0.8 3.2e-07 29.9 0.5 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glycos_transf_2 PF00535.21 EPE36643.1 - 0.031 13.9 0.0 0.07 12.8 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 Gal4_dimer PF03902.8 EPE36643.1 - 0.045 13.6 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain RteC PF09357.5 EPE36643.1 - 0.071 12.9 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 RteC protein GFO_IDH_MocA PF01408.17 EPE36645.1 - 1.1e-18 67.8 0.1 1.8e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPE36645.1 - 0.035 13.8 0.0 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain UCH PF00443.24 EPE36646.1 - 2.2e-26 92.5 0.0 3.2e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPE36646.1 - 4.3e-17 62.4 1.3 4.8e-16 59.0 0.9 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Tim54 PF11711.3 EPE36647.1 - 9e-131 435.9 0.1 1.2e-130 435.6 0.1 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.3 EPE36648.1 - 1.7e-201 670.5 31.1 8.1e-201 668.2 14.5 2.5 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EPE36648.1 - 4.8e-19 67.7 34.0 2.3e-05 23.9 0.2 8.0 7 1 2 10 10 9 6 TPR repeat TPR_14 PF13428.1 EPE36648.1 - 5.8e-18 63.7 13.1 0.0025 18.3 0.1 10.3 5 3 5 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPE36648.1 - 1.3e-17 63.8 26.6 0.0015 18.8 0.0 8.2 6 2 2 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EPE36648.1 - 6.3e-17 61.7 30.9 0.0022 18.6 0.0 8.7 8 2 1 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EPE36648.1 - 4.3e-15 54.3 36.2 0.0013 18.5 0.1 10.6 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPE36648.1 - 3.4e-11 42.4 7.3 0.031 14.4 0.0 7.2 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPE36648.1 - 3.9e-11 42.0 30.6 5.6e-05 22.5 0.1 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPE36648.1 - 3.3e-10 39.7 22.0 0.03 14.2 1.3 7.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EPE36648.1 - 6.3e-08 32.3 12.8 0.00042 20.1 1.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPE36648.1 - 3.4e-06 26.4 17.8 0.077 12.8 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPE36648.1 - 1.9e-05 24.4 4.9 0.38 10.6 0.1 4.6 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EPE36648.1 - 0.00012 22.2 21.5 2.4 8.8 0.2 9.1 10 0 0 10 10 8 2 Tetratricopeptide repeat NAM-associated PF14303.1 EPE36648.1 - 0.002 18.4 5.5 2.1 8.6 2.7 2.7 2 0 0 2 2 2 2 No apical meristem-associated C-terminal domain TPR_7 PF13176.1 EPE36648.1 - 0.0028 17.3 18.6 1.3 8.9 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat RteC PF09357.5 EPE36648.1 - 0.097 12.5 6.5 0.042 13.6 0.4 2.5 2 0 0 2 2 2 0 RteC protein TPR_10 PF13374.1 EPE36648.1 - 0.48 10.4 14.0 18 5.4 0.4 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPE36648.1 - 0.84 10.2 7.6 22 5.8 0.1 4.9 6 0 0 6 6 3 0 Tetratricopeptide repeat Cid2 PF09774.4 EPE36649.1 - 1.4e-49 168.1 0.0 1.6e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Dymeclin PF09742.4 EPE36649.1 - 0.13 10.4 0.0 0.18 9.9 0.0 1.2 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Mito_carr PF00153.22 EPE36650.1 - 3.6e-43 145.2 0.5 1e-15 57.1 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein JAB PF01398.16 EPE36652.1 - 1.7e-06 27.7 0.0 1.1e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AdoHcyase PF05221.12 EPE36653.1 - 3.1e-135 449.3 0.1 3.5e-135 449.1 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EPE36653.1 - 9.5e-84 279.1 1.7 1.4e-83 278.6 1.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPE36653.1 - 6.9e-08 31.8 0.2 1.4e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EPE36653.1 - 0.0014 18.2 0.2 0.0025 17.4 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 EPE36653.1 - 0.0024 17.2 0.5 0.0044 16.4 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TMEM107 PF14995.1 EPE36653.1 - 0.0089 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein ATG11 PF10377.4 EPE36654.1 - 1.3e-37 128.5 0.2 1.3e-37 128.5 0.1 3.9 4 0 0 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.7 EPE36654.1 - 0.00011 21.1 2.5 0.00011 21.1 1.7 5.6 3 2 2 5 5 5 2 Autophagy protein Apg17 ERM PF00769.14 EPE36654.1 - 0.00061 19.3 12.7 0.00061 19.3 8.8 5.8 6 1 0 6 6 6 2 Ezrin/radixin/moesin family Baculo_PEP_C PF04513.7 EPE36654.1 - 0.007 16.1 0.3 0.007 16.1 0.2 5.5 5 1 1 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus SET PF00856.23 EPE36655.1 - 1.3e-14 54.8 0.0 1.9e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 SET domain Ank_2 PF12796.2 EPE36656.1 - 4.1e-133 434.0 29.4 1.7e-24 85.9 0.3 10.2 4 3 6 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 EPE36656.1 - 1.5e-115 371.6 28.3 2.4e-11 42.8 0.0 18.5 18 0 0 18 18 18 16 Ankyrin repeat Ank_4 PF13637.1 EPE36656.1 - 1.2e-93 306.0 23.7 1.6e-11 44.3 0.1 14.8 5 4 9 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE36656.1 - 2.6e-81 259.3 15.3 6.7e-09 35.1 0.0 17.7 17 0 0 17 17 17 14 Ankyrin repeat Ank_5 PF13857.1 EPE36656.1 - 4.7e-69 226.8 32.8 2.4e-11 43.4 0.0 11.1 7 3 4 11 11 11 10 Ankyrin repeats (many copies) NACHT PF05729.7 EPE36656.1 - 1.9e-06 27.6 0.0 5.5e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 EPE36656.1 - 0.008 16.0 0.0 0.13 12.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPE36656.1 - 0.0091 16.1 0.3 0.052 13.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain Lyase_N PF09092.6 EPE36656.1 - 0.0095 15.5 0.2 0.02 14.5 0.1 1.5 1 0 0 1 1 1 1 Lyase, N terminal CENP-H PF05837.7 EPE36657.1 - 2.7e-23 82.1 5.4 2.7e-23 82.1 3.7 2.0 2 0 0 2 2 2 1 Centromere protein H (CENP-H) MRP-S28 PF10213.4 EPE36657.1 - 0.032 14.3 2.2 0.061 13.4 1.5 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein UPF0172 PF03665.8 EPE36657.1 - 0.12 11.8 1.3 0.19 11.2 0.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Methyltransf_12 PF08242.7 EPE36657.1 - 0.12 12.8 0.1 0.23 11.9 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF4599 PF15371.1 EPE36657.1 - 0.24 11.4 1.5 20 5.3 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4599) DUF972 PF06156.8 EPE36657.1 - 1.5 9.2 10.6 0.22 11.8 2.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF972) ADIP PF11559.3 EPE36657.1 - 5.7 6.8 16.5 12 5.7 0.3 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EPE36657.1 - 9.5 5.7 11.2 3.2 7.3 1.5 3.1 2 1 1 3 3 3 0 Septum formation initiator HMG_box PF00505.14 EPE36658.1 - 8e-24 83.7 0.4 8e-24 83.7 0.3 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPE36658.1 - 1.2e-18 67.2 0.6 1.2e-18 67.2 0.4 1.5 2 0 0 2 2 2 1 HMG-box domain DUF1014 PF06244.7 EPE36658.1 - 0.032 14.4 0.9 0.07 13.3 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) RNB PF00773.14 EPE36660.1 - 5.3e-95 318.4 0.4 8.1e-95 317.8 0.3 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EPE36660.1 - 8.3e-09 35.6 0.2 4e-08 33.4 0.2 2.2 1 1 0 1 1 1 1 PIN domain HET PF06985.6 EPE36661.1 - 3.7e-23 82.2 0.1 1e-22 80.8 0.1 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) RVT_3 PF13456.1 EPE36661.1 - 0.19 11.5 1.7 12 5.7 0.0 3.0 3 0 0 3 3 3 0 Reverse transcriptase-like GN3L_Grn1 PF08701.6 EPE36662.1 - 6.7e-24 83.6 12.5 1.5e-23 82.5 8.7 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EPE36662.1 - 4.1e-21 75.1 0.0 1.9e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EPE36662.1 - 6.3e-07 28.8 0.1 1e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPE36662.1 - 4.1e-06 26.7 3.9 0.037 13.8 0.4 4.0 3 1 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EPE36662.1 - 1.1e-05 24.8 0.0 0.0088 15.4 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPE36662.1 - 0.0012 18.1 0.1 0.002 17.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ArgK PF03308.11 EPE36662.1 - 0.0055 15.5 0.1 0.0055 15.5 0.1 1.9 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EPE36662.1 - 0.0066 16.9 0.3 3.3 8.2 0.1 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 EPE36662.1 - 0.014 15.3 1.1 0.13 12.2 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain Arf PF00025.16 EPE36662.1 - 0.031 13.4 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family ORC3_N PF07034.6 EPE36662.1 - 0.095 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Nop14 PF04147.7 EPE36662.1 - 1.1 7.0 21.4 1.5 6.6 14.8 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_17 PF13207.1 EPE36662.1 - 6.6 7.5 6.8 0.49 11.2 0.2 2.4 2 1 0 2 2 2 0 AAA domain HAD_2 PF13419.1 EPE36663.1 - 6.4e-12 46.0 0.0 8.6e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE36663.1 - 1e-11 44.3 0.0 1.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EPE36663.1 - 2.4e-07 31.3 0.0 3.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.1 EPE36663.1 - 0.0086 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 TIP49 PF06068.8 EPE36664.1 - 1e-186 620.4 0.3 1.2e-186 620.2 0.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EPE36664.1 - 2.4e-11 43.9 0.6 3.1e-07 30.6 0.0 2.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPE36664.1 - 7.9e-10 38.1 3.2 1.6e-06 27.3 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPE36664.1 - 1.4e-06 28.3 0.1 0.0023 17.9 0.0 2.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EPE36664.1 - 2.8e-05 24.2 0.3 0.27 11.3 0.1 2.6 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPE36664.1 - 0.00012 21.7 0.0 0.0003 20.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EPE36664.1 - 0.00031 20.4 0.3 0.047 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EPE36664.1 - 0.0014 18.6 0.3 0.0031 17.4 0.1 1.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EPE36664.1 - 0.0018 17.7 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EPE36664.1 - 0.002 17.5 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPE36664.1 - 0.0027 16.8 0.1 0.0066 15.5 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin DUF2075 PF09848.4 EPE36664.1 - 0.0065 15.4 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EPE36664.1 - 0.01 15.2 0.1 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EPE36664.1 - 0.012 14.7 0.1 0.65 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EPE36664.1 - 0.014 15.3 0.0 0.93 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EPE36664.1 - 0.025 13.7 0.1 0.08 12.0 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.1 EPE36664.1 - 0.084 13.6 0.1 0.19 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EPE36664.1 - 0.22 10.7 1.6 0.46 9.6 0.1 2.1 3 0 0 3 3 3 0 PhoH-like protein Homeobox PF00046.24 EPE36665.1 - 1.8e-13 49.8 1.5 3.5e-13 48.9 1.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EPE36665.1 - 0.00016 21.2 0.7 0.00057 19.5 0.2 2.2 2 0 0 2 2 2 1 Homeobox KN domain HET PF06985.6 EPE36667.1 - 8.5e-25 87.5 0.2 1.9e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldedh PF00171.17 EPE36668.1 - 4.2e-108 361.6 0.0 5.2e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HLH PF00010.21 EPE36669.1 - 6.9e-13 48.0 0.1 1.5e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Meiotic_rec114 PF03525.9 EPE36669.1 - 0.035 12.6 3.9 0.047 12.1 2.7 1.1 1 0 0 1 1 1 0 Meiotic recombination protein rec114 Cellulase PF00150.13 EPE36670.1 - 4.6e-08 32.5 0.3 6.9e-08 32.0 0.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_43 PF04616.9 EPE36673.1 - 2.7e-49 167.8 4.2 3.2e-49 167.5 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FAD_binding_4 PF01565.18 EPE36674.1 - 8.3e-17 60.9 0.3 1.9e-16 59.8 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPE36674.1 - 3.6e-13 49.1 0.0 7.5e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like AAA PF00004.24 EPE36676.1 - 1.4e-18 67.3 0.0 4.7e-18 65.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EPE36676.1 - 0.00041 20.4 0.2 0.0047 17.0 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 EPE36676.1 - 0.0057 16.7 0.2 0.096 12.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF4473 PF14747.1 EPE36676.1 - 0.073 13.3 0.4 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) AAA_16 PF13191.1 EPE36676.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Tic20 PF09685.5 EPE36677.1 - 1.8e-05 24.6 1.7 2.6e-05 24.1 1.2 1.1 1 0 0 1 1 1 1 Tic20-like protein DUF4260 PF14079.1 EPE36677.1 - 0.21 11.4 1.6 0.32 10.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) Vac_ImportDeg PF09783.4 EPE36678.1 - 3.1e-67 225.4 1.5 4.2e-67 225.0 1.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.9 EPE36679.1 - 9.3e-75 249.1 0.2 1.1e-74 248.8 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.15 EPE36680.1 - 1.7e-93 313.7 7.6 3.4e-93 312.7 5.3 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 EPE36680.1 - 2.7e-62 208.5 2.2 5.7e-62 207.5 1.5 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 EPE36680.1 - 3.3e-62 207.9 0.0 8.7e-62 206.6 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 EPE36680.1 - 1.2e-10 41.5 2.8 5.6e-06 26.5 0.0 4.2 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EPE36680.1 - 0.00021 21.2 6.4 0.0045 16.8 0.1 3.9 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EPE36680.1 - 0.00077 19.3 0.2 0.45 10.7 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat RE_Alw26IDE PF09665.5 EPE36680.1 - 0.019 13.7 0.6 0.51 8.9 0.1 2.8 2 1 1 3 3 3 0 Type II restriction endonuclease (RE_Alw26IDE) HEAT_EZ PF13513.1 EPE36680.1 - 0.023 15.1 0.4 3 8.4 0.0 4.1 3 1 1 4 4 4 0 HEAT-like repeat DAGK_cat PF00781.19 EPE36681.1 - 1.7e-24 85.6 0.0 7.2e-24 83.6 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.7 EPE36682.1 - 1e-58 198.3 0.0 1.2e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 SET PF00856.23 EPE36683.1 - 3.9e-21 76.0 0.1 1.2e-20 74.4 0.0 1.8 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EPE36683.1 - 3.4e-06 27.2 3.9 1.3e-05 25.3 0.6 2.2 2 0 0 2 2 2 1 Pre-SET motif p450 PF00067.17 EPE36686.1 - 1.2e-48 165.8 0.1 2.3e-24 85.7 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 CUE PF02845.11 EPE36687.1 - 7.9e-12 44.4 0.0 1.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 EPE36687.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain CENP-T PF15511.1 EPE36689.1 - 2.5 7.2 27.5 3.3 6.8 19.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T MFS_1 PF07690.11 EPE36690.1 - 7.8e-38 130.0 50.1 1.7e-36 125.7 34.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE36690.1 - 1.7e-10 40.1 17.4 1.7e-10 40.1 12.1 3.0 3 1 1 4 4 4 2 Sugar (and other) transporter Spore_III_AF PF09581.5 EPE36690.1 - 0.16 11.8 0.6 0.39 10.5 0.4 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) PgaD PF13994.1 EPE36690.1 - 0.7 9.3 8.3 8 5.9 0.0 3.8 3 1 1 4 4 4 0 PgaD-like protein Collagen PF01391.13 EPE36691.1 - 1.9e-26 91.3 118.7 6.4e-09 35.2 17.5 6.0 3 2 2 5 5 5 5 Collagen triple helix repeat (20 copies) WSC PF01822.14 EPE36691.1 - 4.4e-16 58.5 11.9 4.4e-16 58.5 8.2 1.8 2 0 0 2 2 2 1 WSC domain DUF2433 PF10360.4 EPE36693.1 - 0.14 12.4 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) NACHT PF05729.7 EPE36694.1 - 0.0016 18.1 0.3 0.0064 16.1 0.2 1.9 1 1 0 1 1 1 1 NACHT domain BAG PF02179.11 EPE36695.1 - 0.0025 17.8 2.0 0.0034 17.4 0.5 1.9 2 0 0 2 2 2 1 BAG domain DUF285 PF03382.9 EPE36695.1 - 0.018 14.6 0.4 0.033 13.7 0.3 1.4 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 KTI12 PF08433.5 EPE36695.1 - 0.028 13.6 4.6 0.04 13.1 0.6 2.3 1 1 1 2 2 2 0 Chromatin associated protein KTI12 FliD_N PF02465.13 EPE36695.1 - 0.65 10.4 4.4 2.8 8.3 0.1 2.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus UQ_con PF00179.21 EPE36696.1 - 6.2e-42 142.3 0.0 7e-42 142.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPE36696.1 - 2.7e-05 23.9 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPE36696.1 - 0.02 14.8 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 EPE36696.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 UEV domain RabGAP-TBC PF00566.13 EPE36697.1 - 3.6e-38 131.1 0.0 5.7e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Kinesin PF00225.18 EPE36698.1 - 2.8e-53 180.7 0.0 2.8e-52 177.5 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain HALZ PF02183.13 EPE36698.1 - 0.02 14.6 1.2 0.036 13.7 0.1 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Exonuc_VII_L PF02601.10 EPE36698.1 - 0.021 14.0 1.5 0.033 13.3 1.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF812 PF05667.6 EPE36698.1 - 0.025 13.0 9.8 0.072 11.5 6.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Mitofilin PF09731.4 EPE36698.1 - 0.23 10.0 10.3 0.38 9.3 7.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF972 PF06156.8 EPE36698.1 - 6.3 7.1 8.7 8.1 6.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Peptidase_S24 PF00717.18 EPE36699.1 - 3.5e-08 32.9 0.0 5.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S9 PF00326.16 EPE36701.1 - 2.5e-38 131.4 0.0 3.6e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE36701.1 - 9.1e-11 41.7 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPE36701.1 - 2.3e-08 34.1 0.1 5.1e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EPE36701.1 - 5.3e-07 29.1 0.0 1.9e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EPE36701.1 - 6.6e-06 25.7 0.0 8.3e-05 22.1 0.1 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.23 EPE36701.1 - 0.00012 20.9 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_4 PF08386.5 EPE36701.1 - 0.0043 16.9 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.6 EPE36701.1 - 0.02 14.6 0.0 0.28 10.8 0.0 2.2 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EPE36701.1 - 0.062 12.8 0.0 0.2 11.2 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 EPE36701.1 - 0.065 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase Glyoxalase_2 PF12681.2 EPE36701.1 - 0.066 13.8 0.1 24 5.5 0.0 3.1 2 1 0 2 2 2 0 Glyoxalase-like domain Abhydrolase_2 PF02230.11 EPE36701.1 - 0.13 11.6 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF126 PF01989.11 EPE36701.1 - 0.13 11.9 0.1 0.46 10.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF126 Glyco_hydro_31 PF01055.21 EPE36702.1 - 8.3e-165 548.8 1.6 1.1e-164 548.5 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Amidase PF01425.16 EPE36703.1 - 1.4e-96 324.0 0.0 1.7e-96 323.8 0.0 1.0 1 0 0 1 1 1 1 Amidase FAD_binding_3 PF01494.14 EPE36704.1 - 2.9e-75 253.5 0.0 3.8e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EPE36704.1 - 9.3e-35 119.7 0.0 4.3e-34 117.5 0.0 2.1 3 0 0 3 3 3 1 Phenol hydroxylase, C-terminal dimerisation domain RNA_pol_Rpb2_1 PF04563.10 EPE36704.1 - 0.0019 17.1 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit HPD PF05044.7 EPE36704.1 - 0.031 13.9 0.0 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 Homeo-prospero domain Ald_Xan_dh_C2 PF02738.13 EPE36705.1 - 9.3e-181 601.8 0.6 1.2e-180 601.4 0.4 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EPE36705.1 - 4.3e-39 133.6 0.0 8.1e-39 132.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EPE36705.1 - 1.2e-32 111.8 0.1 1.2e-31 108.7 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EPE36705.1 - 2.9e-25 87.9 0.0 6.9e-25 86.7 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.17 EPE36705.1 - 3.1e-19 69.1 0.0 6.3e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.22 EPE36705.1 - 4.9e-09 35.8 0.0 1.8e-08 33.9 0.0 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_2 PF03446.10 EPE36705.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Oxidored_FMN PF00724.15 EPE36706.1 - 3.3e-89 299.2 0.0 4.9e-89 298.6 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.13 EPE36707.1 - 2.4e-37 128.2 5.8 4.3e-37 127.3 4.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPE36707.1 - 4.6e-07 29.7 12.1 0.00085 19.5 2.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPE36707.1 - 3.8e-05 23.7 10.2 0.035 14.4 1.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger FAD_binding_3 PF01494.14 EPE36708.1 - 4e-19 68.8 0.1 6.6e-13 48.4 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EPE36708.1 - 2e-09 36.8 2.2 0.00098 18.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EPE36708.1 - 7.4e-08 31.4 3.5 0.0002 20.1 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EPE36708.1 - 2.7e-06 27.3 0.7 1e-05 25.4 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE36708.1 - 2.6e-05 23.3 0.1 3.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPE36708.1 - 3.5e-05 23.9 0.0 5.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE36708.1 - 0.00021 21.0 0.2 0.00075 19.2 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EPE36708.1 - 0.00041 19.5 3.2 0.048 12.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EPE36708.1 - 0.00056 18.4 4.0 0.0055 15.2 2.8 2.0 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EPE36708.1 - 0.0056 15.5 2.5 0.0056 15.5 1.7 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EPE36708.1 - 0.0076 16.6 1.5 0.013 15.8 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EPE36708.1 - 0.031 13.9 0.2 0.053 13.1 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EPE36708.1 - 0.044 13.6 2.0 0.12 12.2 1.4 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EPE36708.1 - 0.074 11.8 0.0 0.25 10.1 0.0 1.8 1 1 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 EPE36708.1 - 0.076 12.5 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EPE36708.1 - 0.18 10.6 4.9 1.1 8.0 2.7 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A CFEM PF05730.6 EPE36709.1 - 1.2e-12 47.4 8.8 3e-12 46.1 6.1 1.7 1 0 0 1 1 1 1 CFEM domain Tubulin_3 PF14881.1 EPE36710.1 - 2.5e-79 264.9 0.1 1e-78 262.9 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 EPE36710.1 - 9.1e-41 138.5 2.8 2e-40 137.4 0.1 2.6 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EPE36710.1 - 2.2e-06 27.6 0.0 0.088 12.6 0.0 3.1 3 0 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain SMP_2 PF10144.4 EPE36710.1 - 0.067 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin AhpC-TSA_2 PF13911.1 EPE36711.1 - 6.7e-09 35.6 0.0 9.4e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EPE36711.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPE36711.1 - 7.1e-05 22.3 0.0 0.012 15.1 0.0 2.1 1 1 0 2 2 2 2 Redoxin HET PF06985.6 EPE36712.1 - 1.7e-22 80.0 0.0 3.1e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NADase_NGA PF07461.6 EPE36712.1 - 0.0032 16.2 0.0 0.0046 15.7 0.0 1.1 1 0 0 1 1 1 1 Nicotine adenine dinucleotide glycohydrolase (NADase) tRNA-synt_1c PF00749.16 EPE36713.1 - 3.1e-90 302.0 0.0 4.2e-90 301.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EPE36713.1 - 3.3e-33 114.8 0.7 8.9e-33 113.3 0.4 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EPE36713.1 - 0.00044 20.6 0.0 0.0012 19.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPE36713.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3945 PF13101.1 EPE36713.1 - 0.15 11.3 0.5 1.8 7.9 0.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3945) Bromodomain PF00439.20 EPE36714.1 - 3.3e-24 84.6 0.1 6.6e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 EPE36714.1 - 1e-08 35.0 0.3 2.3e-08 33.9 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPE36714.1 - 1.3e-08 34.8 0.5 2.7e-08 33.8 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CoA_transf_3 PF02515.12 EPE36715.1 - 3.9e-31 107.7 0.0 6.7e-30 103.7 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III MFS_1 PF07690.11 EPE36717.1 - 1.9e-39 135.4 35.6 1.9e-39 135.4 24.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE36717.1 - 1.4e-11 43.6 25.8 2.2e-11 43.0 17.9 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EPE36717.1 - 2.6e-07 29.2 2.2 5.2e-07 28.2 1.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 EPE36718.1 - 1.9e-13 49.8 0.0 3.4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3336 PF11815.3 EPE36719.1 - 2.1e-47 160.2 4.2 3.4e-47 159.5 2.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EPE36719.1 - 7.2e-20 71.7 0.2 8.1e-19 68.3 0.0 2.4 2 0 0 2 2 2 1 Patatin-like phospholipase DUF2048 PF09752.4 EPE36719.1 - 0.018 13.9 0.1 0.48 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) DUF1669 PF07894.7 EPE36719.1 - 0.063 12.4 0.3 0.33 10.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1669) Arf PF00025.16 EPE36720.1 - 3.6e-61 205.4 0.0 2.7e-60 202.5 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EPE36720.1 - 6.8e-12 44.7 0.1 2.6e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EPE36720.1 - 6.3e-07 29.9 0.0 9.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EPE36720.1 - 1.3e-06 27.7 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPE36720.1 - 1.2e-05 25.1 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EPE36720.1 - 2e-05 23.8 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EPE36720.1 - 2.8e-05 23.5 0.0 8.2e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 EPE36720.1 - 0.00076 18.9 0.1 0.0097 15.3 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Tegument_dsDNA PF12818.2 EPE36720.1 - 0.025 13.4 0.0 0.052 12.4 0.0 1.5 1 0 0 1 1 1 0 dsDNA viral tegument protein DUF2457 PF10446.4 EPE36721.1 - 3e-150 500.9 55.7 4.9e-102 342.0 28.6 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF2457) TFIIA PF03153.8 EPE36721.1 - 4e-05 23.6 12.1 4e-05 23.6 8.4 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 EPE36721.1 - 0.09 10.7 23.0 0.045 11.7 11.5 2.2 2 0 0 2 2 2 0 CDC45-like protein Daxx PF03344.10 EPE36721.1 - 0.38 9.1 31.3 0.017 13.6 17.1 2.0 2 0 0 2 2 2 0 Daxx Family ATP-synt_DE_N PF02823.11 EPE36722.1 - 3.9e-20 71.4 0.1 5.7e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain IncA PF04156.9 EPE36723.1 - 0.014 14.9 0.6 0.031 13.8 0.4 1.5 1 0 0 1 1 1 0 IncA protein Spc24 PF08286.6 EPE36723.1 - 0.29 10.8 3.3 0.68 9.6 2.3 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Acetyltransf_1 PF00583.19 EPE36724.1 - 1.4e-09 37.8 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPE36724.1 - 8.3e-05 22.2 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPE36724.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE36724.1 - 0.075 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MarR_2 PF12802.2 EPE36725.1 - 0.063 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 MarR family HET PF06985.6 EPE36726.1 - 0.0018 18.4 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1996 PF09362.5 EPE36728.1 - 3.5e-87 291.9 0.9 4.4e-87 291.6 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Lys PF00062.15 EPE36728.1 - 0.087 12.8 0.2 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family Glyco_transf_36 PF06165.6 EPE36729.1 - 4.4e-22 78.0 0.0 9.4e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 36 GT36_AF PF06205.6 EPE36729.1 - 2e-07 30.6 0.0 3.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase 36 associated family Bac_rhamnosid PF05592.6 EPE36729.1 - 0.0013 17.0 0.0 0.0037 15.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase GDE_C PF06202.9 EPE36729.1 - 0.0013 17.5 0.0 0.0031 16.2 0.0 1.5 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase MFS_1 PF07690.11 EPE36730.1 - 4.8e-22 78.1 15.5 6.4e-22 77.7 10.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily GDPD PF03009.12 EPE36731.1 - 5.4e-43 147.3 0.0 9.3e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EPE36731.1 - 3.8e-24 84.8 0.0 7.3e-07 29.4 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPE36731.1 - 3.7e-23 80.0 2.1 4.9e-08 32.4 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EPE36731.1 - 5.9e-19 67.6 2.0 8e-06 25.9 0.0 4.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE36731.1 - 4.4e-18 63.5 0.2 4.1e-06 26.5 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EPE36731.1 - 1e-15 57.7 0.3 1.4e-06 28.6 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) SPX PF03105.14 EPE36731.1 - 5.1e-08 33.0 0.8 2.4e-06 27.5 0.3 3.0 2 1 0 2 2 2 1 SPX domain Aldo_ket_red PF00248.16 EPE36732.1 - 1.9e-55 187.6 0.0 2.2e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PSD5 PF07637.6 EPE36733.1 - 7.4e-10 38.7 0.1 61 3.7 0.0 8.0 5 3 3 8 8 8 0 Protein of unknown function (DUF1595) IglC PF11550.3 EPE36733.1 - 0.0001 21.6 0.2 12 5.1 0.0 4.0 3 1 1 4 4 4 1 Intracellular growth locus C protein DUF276 PF03434.8 EPE36733.1 - 0.011 14.7 0.2 24 3.7 0.0 4.3 2 2 3 5 5 5 0 DUF276 tRNA_int_endo_N PF02778.9 EPE36733.1 - 0.11 12.0 5.3 32 4.1 0.1 4.6 1 1 4 5 5 5 0 tRNA intron endonuclease, N-terminal domain DUF2382 PF09557.5 EPE36733.1 - 1.3 8.9 14.9 4.6 7.1 0.1 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF2382) DUF1947 PF09183.5 EPE36733.1 - 6.1 6.6 20.4 1.6e+02 2.1 0.0 7.8 3 3 6 9 9 9 0 Domain of unknown function (DUF1947) Ras PF00071.17 EPE36734.1 - 2.3e-57 192.9 0.0 2.7e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE36734.1 - 2.2e-19 70.0 0.0 3.2e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE36734.1 - 1.8e-13 50.1 0.0 2.5e-13 49.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPE36734.1 - 5.3e-06 26.0 0.0 1.3e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPE36734.1 - 8.2e-06 25.1 0.0 9.9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPE36734.1 - 0.00032 20.6 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EPE36734.1 - 0.0032 17.4 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPE36734.1 - 0.076 13.1 0.0 0.23 11.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain Kri1_C PF12936.2 EPE36735.1 - 3e-28 97.5 0.2 3e-28 97.5 0.2 4.0 3 1 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 EPE36735.1 - 3.4e-26 91.4 19.9 3.4e-26 91.4 13.8 5.6 4 2 2 6 6 6 1 KRI1-like family EBP PF05241.7 EPE36736.1 - 2.3e-05 23.4 0.5 2.3e-05 23.4 0.3 1.9 2 0 0 2 2 2 1 Emopamil binding protein Scs3p PF10261.4 EPE36737.1 - 1.3e-65 220.7 3.0 1.6e-65 220.4 2.1 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM APH PF01636.18 EPE36740.1 - 1.2e-13 51.4 0.0 3.5e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE36740.1 - 0.0016 18.0 0.0 0.0042 16.6 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPE36740.1 - 0.0091 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EPE36740.1 - 0.011 14.4 0.1 0.016 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Glyco_hydro_3 PF00933.16 EPE36741.1 - 2.4e-85 286.1 0.0 3.4e-85 285.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE36741.1 - 1.2e-52 178.7 0.0 3.9e-52 177.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE36741.1 - 9.7e-17 60.6 0.0 2.1e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain K_trans PF02705.11 EPE36742.1 - 1.1e-181 604.7 21.7 1.5e-181 604.4 15.0 1.1 1 0 0 1 1 1 1 K+ potassium transporter DUF485 PF04341.7 EPE36742.1 - 2.4 7.9 0.0 2.4 7.9 0.0 4.4 4 1 1 5 5 5 0 Protein of unknown function, DUF485 Fungal_trans PF04082.13 EPE36743.1 - 4.5e-29 101.1 0.0 8.1e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE36743.1 - 1.6e-09 37.5 10.9 2.6e-09 36.8 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polyoma_coat2 PF00761.15 EPE36743.1 - 0.056 12.9 2.5 0.1 12.0 1.8 1.4 1 0 0 1 1 1 0 Polyomavirus coat protein DUF2132 PF09905.4 EPE36743.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2132) PH PF00169.24 EPE36744.1 - 7.6e-08 32.4 0.0 2.2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 EPE36744.1 - 0.0073 15.8 0.0 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 GRAM domain DUF3074 PF11274.3 EPE36745.1 - 6.2e-62 208.5 1.9 6.2e-61 205.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) TPR_MLP1_2 PF07926.7 EPE36745.1 - 0.023 14.4 33.7 0.067 12.9 23.4 1.8 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4618 PF15397.1 EPE36745.1 - 0.041 13.2 20.2 0.066 12.5 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) HAUS6_N PF14661.1 EPE36745.1 - 0.69 9.2 29.0 0.11 11.8 8.2 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus APH PF01636.18 EPE36747.1 - 2.1e-09 37.4 0.2 2.8e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EPE36747.1 - 0.001 17.8 0.0 0.0013 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EPE36747.1 - 0.0022 17.6 0.1 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase GST_N_3 PF13417.1 EPE36748.1 - 3.2e-11 43.2 0.1 7.2e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPE36748.1 - 9.9e-10 38.2 0.0 1.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE36748.1 - 0.00026 20.8 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PAS_9 PF13426.1 EPE36748.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 PAS domain GST_C PF00043.20 EPE36748.1 - 0.028 14.3 0.0 0.079 12.9 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Nol1_Nop2_Fmu PF01189.12 EPE36749.1 - 9.4e-18 64.5 0.0 6.1e-13 48.7 0.0 2.5 2 1 0 2 2 2 2 NOL1/NOP2/sun family Abhydrolase_6 PF12697.2 EPE36751.1 - 2.6e-05 24.2 0.2 6.3e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EPE36751.1 - 0.079 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase CBM_1 PF00734.13 EPE36753.1 - 1.4e-09 37.4 9.3 1.4e-09 37.4 6.4 1.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Totivirus_coat PF05518.6 EPE36753.1 - 3.2 5.4 9.4 3.8 5.2 6.5 1.0 1 0 0 1 1 1 0 Totivirus coat protein Prp18 PF02840.10 EPE36754.1 - 7e-50 168.6 0.0 7e-50 168.6 0.0 2.4 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EPE36754.1 - 2.2e-11 42.7 1.0 2.2e-11 42.7 0.7 2.8 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like SAPS PF04499.10 EPE36754.1 - 0.1 11.2 3.3 0.097 11.2 2.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF-3c_N PF05470.7 EPE36754.1 - 0.3 9.1 13.8 0.4 8.7 9.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC27 PF09507.5 EPE36754.1 - 0.67 9.1 23.8 0.94 8.6 16.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ycf1 PF05758.7 EPE36754.1 - 7.2 4.1 11.3 8.6 3.9 7.8 1.1 1 0 0 1 1 1 0 Ycf1 SAP18 PF06487.7 EPE36755.1 - 1.4e-44 150.7 0.0 1.7e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF805 PF05656.9 EPE36756.1 - 0.026 14.3 1.2 0.029 14.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) PspC PF04024.7 EPE36756.1 - 0.2 11.1 1.3 0.75 9.3 0.9 1.7 2 0 0 2 2 2 0 PspC domain GST_N_2 PF13409.1 EPE36757.1 - 4.7e-10 39.3 0.1 8.8e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPE36757.1 - 2.9e-09 37.0 0.0 4.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPE36757.1 - 2.7e-07 30.6 0.1 5.9e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain DUF342 PF03961.8 EPE36759.1 - 0.0016 16.9 0.8 0.002 16.5 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Snf7 PF03357.16 EPE36759.1 - 0.038 13.3 0.3 0.081 12.2 0.2 1.5 1 0 0 1 1 1 0 Snf7 Bacillus_HBL PF05791.6 EPE36759.1 - 0.04 13.2 2.1 0.077 12.3 0.7 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) UPF0172 PF03665.8 EPE36759.1 - 0.054 12.9 0.2 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Fib_alpha PF08702.5 EPE36759.1 - 0.06 13.4 3.7 0.66 10.0 1.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 EPE36759.1 - 0.15 11.7 3.1 0.17 11.5 1.2 1.7 1 1 1 2 2 2 0 Mnd1 family Laminin_II PF06009.7 EPE36759.1 - 0.15 11.8 2.5 0.81 9.4 0.4 2.5 1 1 1 2 2 2 0 Laminin Domain II DUF4200 PF13863.1 EPE36759.1 - 0.18 11.7 7.1 5.9 6.8 3.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 EPE36759.1 - 0.53 9.8 5.3 1.5 8.4 3.6 1.8 1 1 0 1 1 1 0 IncA protein Ank_5 PF13857.1 EPE36760.1 - 0.00014 21.9 1.2 0.0039 17.4 0.4 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPE36760.1 - 0.0004 20.6 0.0 0.0071 16.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE36760.1 - 0.0063 17.0 0.4 1.2 9.7 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE36760.1 - 0.0068 16.5 0.8 0.12 12.7 0.3 3.1 3 0 0 3 3 3 1 Ankyrin repeat PHD PF00628.24 EPE36761.1 - 6.6e-09 35.3 6.3 1.1e-08 34.6 4.4 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EPE36761.1 - 0.00054 20.1 0.1 0.0018 18.5 0.0 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 EPE36761.1 - 0.05 13.7 0.6 0.11 12.6 0.4 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 EPE36761.1 - 0.093 12.7 2.5 0.16 11.9 1.7 1.4 1 0 0 1 1 1 0 RING-like domain zf-C2H2_4 PF13894.1 EPE36763.1 - 0.017 15.4 2.1 0.064 13.6 1.5 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPE36763.1 - 0.03 14.6 0.9 6.8 7.1 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 EPE36763.1 - 0.056 13.2 1.7 0.12 12.1 1.2 1.6 1 0 0 1 1 1 0 BED zinc finger zf-C2H2 PF00096.21 EPE36763.1 - 0.13 12.6 7.2 0.06 13.7 2.5 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3602 PF12223.3 EPE36764.1 - 3.2e-11 43.4 18.3 5e-05 23.6 3.3 3.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) NACHT PF05729.7 EPE36765.1 - 2.3e-10 40.3 2.4 5.6e-09 35.8 1.4 2.9 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EPE36765.1 - 7e-05 22.9 0.0 0.00026 21.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPE36765.1 - 0.00018 21.5 0.0 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 EPE36765.1 - 0.022 15.1 0.3 0.069 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EPE36765.1 - 0.034 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 EPE36765.1 - 0.035 14.2 0.0 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Ank PF00023.25 EPE36765.1 - 0.037 13.8 0.0 1.4 8.8 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat FlgM PF04316.8 EPE36765.1 - 0.043 13.7 0.1 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM SH3_1 PF00018.23 EPE36766.1 - 8.4e-11 41.0 0.0 1.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain CorA PF01544.13 EPE36766.1 - 2.2e-10 40.0 0.0 2.2e-10 40.0 0.0 2.9 4 0 0 4 4 4 1 CorA-like Mg2+ transporter protein SH3_9 PF14604.1 EPE36766.1 - 1.8e-09 37.0 0.0 4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPE36766.1 - 4.9e-07 29.1 0.0 1.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CCDC155 PF14662.1 EPE36766.1 - 0.86 9.1 8.3 1.9 8.0 5.8 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 zf-H2C2_2 PF13465.1 EPE36767.1 - 4.3e-05 23.5 3.3 4.3e-05 23.5 2.3 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EPE36767.1 - 6.6e-05 23.0 2.7 6.6e-05 23.0 1.9 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EPE36767.1 - 0.0025 17.9 0.7 0.0076 16.3 0.5 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EPE36767.1 - 0.0035 17.5 0.7 0.0035 17.5 0.5 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger DUF504 PF04457.7 EPE36768.1 - 5.1e-06 26.5 0.2 1.4e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF504) DUF433 PF04255.9 EPE36768.1 - 0.019 14.3 0.0 0.14 11.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF433) LIX1 PF14954.1 EPE36768.1 - 0.1 11.5 0.0 0.32 9.9 0.0 1.8 2 0 0 2 2 2 0 Limb expression 1 DUF1295 PF06966.7 EPE36769.1 - 9.8e-39 133.0 9.8 1.3e-38 132.5 6.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Topoisom_bac PF01131.15 EPE36770.1 - 1.7e-88 297.1 0.0 1.6e-83 280.7 0.0 2.0 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EPE36770.1 - 8e-17 61.0 0.0 1.6e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Toprim domain API5 PF05918.6 EPE36770.1 - 0.33 9.4 1.8 0.52 8.7 1.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Stb3 PF10330.4 EPE36771.1 - 1.9e-37 126.8 0.0 3.5e-37 125.9 0.0 1.5 1 0 0 1 1 1 1 Putative Sin3 binding protein DnaJ PF00226.26 EPE36773.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EPE36773.1 - 2.1e-07 30.8 0.2 4.6e-07 29.6 0.2 1.6 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 EPE36773.1 - 0.025 13.8 1.4 0.025 13.8 1.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) Ribosomal_L24e PF01246.15 EPE36774.1 - 2.1e-05 24.2 0.1 2.1e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e DUF3293 PF11697.3 EPE36774.1 - 0.031 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) SnoaL_4 PF13577.1 EPE36775.1 - 0.00085 19.2 0.2 0.0028 17.5 0.1 1.8 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EPE36775.1 - 0.038 14.2 0.0 0.046 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 EPE36775.1 - 0.11 12.9 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain DUF605 PF04652.11 EPE36776.1 - 2.6 7.3 17.6 3.5 6.9 12.2 1.1 1 0 0 1 1 1 0 Vta1 like Mit_ribos_Mrp51 PF11709.3 EPE36778.1 - 4.8e-80 269.0 0.5 6e-80 268.7 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Lzipper-MIP1 PF14389.1 EPE36778.1 - 0.078 13.0 0.1 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Aminotran_1_2 PF00155.16 EPE36780.1 - 7.8e-17 61.2 0.0 1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EPE36780.1 - 0.0017 17.0 0.0 0.019 13.5 0.0 2.1 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase CmcH_NodU PF02543.10 EPE36780.1 - 0.0019 17.3 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyltransferase RNase_Zc3h12a PF11977.3 EPE36780.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain F1F0-ATPsyn_F PF10791.4 EPE36782.1 - 5.1e-41 138.8 0.8 6e-41 138.5 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EPE36782.1 - 0.0017 18.4 0.2 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 EPE36783.1 - 1.7e-37 127.2 1.2 3.4e-37 126.3 0.8 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region OB_NTP_bind PF07717.11 EPE36784.1 - 2e-28 98.4 0.0 8.6e-28 96.4 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPE36784.1 - 2.2e-26 91.8 0.1 2.2e-26 91.8 0.1 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPE36784.1 - 2.4e-12 46.5 0.0 6.4e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EPE36784.1 - 7.1e-10 38.8 1.3 1.4e-09 37.8 0.9 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EPE36784.1 - 1.1e-06 28.2 0.1 2.2e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EPE36784.1 - 0.00013 21.0 0.3 0.00046 19.1 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 EPE36784.1 - 0.00034 20.7 0.0 0.00088 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EPE36784.1 - 0.0076 15.8 0.2 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPE36784.1 - 0.012 15.3 0.4 0.033 13.9 0.1 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 EPE36784.1 - 0.084 12.7 0.1 0.57 10.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPE36784.1 - 0.12 12.6 0.2 1.4 9.2 0.2 2.5 1 1 0 1 1 1 0 ABC transporter Motile_Sperm PF00635.21 EPE36786.1 - 5.4e-25 87.1 0.7 2.1e-24 85.2 0.2 2.1 1 1 1 2 2 2 1 MSP (Major sperm protein) domain SLT_2 PF13406.1 EPE36786.1 - 0.033 13.0 0.1 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain FixG_C PF11614.3 EPE36786.1 - 0.038 14.0 0.0 0.1 12.7 0.0 1.7 1 1 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase UBX PF00789.15 EPE36787.1 - 5e-05 23.2 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain zf-C2H2_jaz PF12171.3 EPE36787.1 - 0.0079 16.3 0.2 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPE36787.1 - 0.017 15.3 0.1 0.034 14.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EPE36787.1 - 0.058 13.7 0.2 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EPE36787.1 - 0.063 13.3 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) UBA PF00627.26 EPE36787.1 - 0.068 13.0 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 UBA/TS-N domain CpXC PF14353.1 EPE36787.1 - 3.3 7.7 10.6 0.62 10.0 4.3 2.0 1 1 1 2 2 2 0 CpXC protein DUF3650 PF12368.3 EPE36787.1 - 5.5 6.5 6.4 2 7.9 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) Rad52_Rad22 PF04098.10 EPE36788.1 - 1.5e-60 203.3 0.1 2.5e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Nucleoplasmin PF03066.10 EPE36790.1 - 1.4 8.4 8.9 2.2 7.7 6.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin Aminotran_5 PF00266.14 EPE36791.1 - 2.8e-14 52.6 0.0 3.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 EPE36791.1 - 0.0037 15.7 0.0 0.0048 15.4 0.0 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_1_2 PF00155.16 EPE36791.1 - 0.023 13.6 0.0 7.6 5.3 0.0 2.8 3 0 0 3 3 3 0 Aminotransferase class I and II Peptidase_M29 PF02073.10 EPE36791.1 - 0.076 11.7 0.0 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Thermophilic metalloprotease (M29) Pyridoxal_deC PF00282.14 EPE36791.1 - 0.17 10.3 0.0 0.31 9.4 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Meth_synt_2 PF01717.13 EPE36792.1 - 7.4e-146 485.2 0.0 5.6e-139 462.6 0.0 3.0 3 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EPE36792.1 - 1e-122 409.3 0.1 1.1e-110 369.8 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Bac_small_YrzI PF09501.5 EPE36792.1 - 0.92 9.4 3.8 1.8 8.5 1.7 2.2 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) RasGEF PF00617.14 EPE36793.1 - 1.8e-58 197.4 0.0 4.3e-58 196.1 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EPE36793.1 - 8.7e-20 70.7 0.0 3.8e-19 68.7 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 EPE36793.1 - 2.7e-06 26.8 0.0 7e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPE36793.1 - 4.2e-05 22.8 0.0 9.2e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain FA_desaturase PF00487.19 EPE36794.1 - 5.8e-29 101.3 14.1 8.2e-29 100.8 9.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EPE36794.1 - 4.4e-21 73.8 0.1 7.2e-21 73.1 0.1 1.3 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Aconitase PF00330.15 EPE36796.1 - 8.6e-160 532.2 0.0 1.7e-159 531.2 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPE36796.1 - 2.6e-39 134.3 0.0 4.1e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain WD40 PF00400.27 EPE36797.1 - 1.7e-50 167.1 20.3 5.4e-11 41.9 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EPE36797.1 - 3.5e-06 25.4 4.3 0.28 9.2 0.0 4.7 3 1 1 5 5 5 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 EPE36797.1 - 0.0003 19.1 0.0 0.00058 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) eIF2A PF08662.6 EPE36797.1 - 0.00034 20.3 2.0 0.0083 15.8 0.0 3.1 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 EPE36797.1 - 0.0014 17.5 0.6 6.3 5.6 0.0 3.5 3 1 1 4 4 4 2 Protein of unknown function (DUF1513) Hira PF07569.6 EPE36797.1 - 0.006 15.8 1.6 1.9 7.6 0.1 3.5 1 1 2 3 3 3 1 TUP1-like enhancer of split Coatomer_WDAD PF04053.9 EPE36797.1 - 0.011 14.5 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Nucleoporin_N PF08801.6 EPE36797.1 - 0.026 13.2 0.4 0.82 8.3 0.0 3.0 1 1 1 2 2 2 0 Nup133 N terminal like HPS3_N PF14761.1 EPE36797.1 - 0.12 11.7 0.0 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 HEAT PF02985.17 EPE36798.1 - 8.2e-13 47.2 0.8 0.24 11.5 0.0 5.5 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.1 EPE36798.1 - 1.4e-06 28.5 0.0 0.0047 17.3 0.1 3.1 2 1 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 EPE36798.1 - 3.4e-06 27.2 0.0 0.00037 20.6 0.0 3.1 1 1 3 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.12 EPE36798.1 - 1.2e-05 24.5 0.0 2.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EPE36798.1 - 0.0002 20.6 0.0 0.00039 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.2 EPE36798.1 - 0.0093 15.8 0.0 0.052 13.4 0.0 1.9 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EPE36798.1 - 0.037 13.3 0.0 1.3 8.3 0.0 2.5 1 1 1 2 2 2 0 CLASP N terminal Adaptin_N PF01602.15 EPE36798.1 - 0.072 11.3 0.0 0.22 9.8 0.0 1.6 1 1 1 2 2 2 0 Adaptin N terminal region PHD PF00628.24 EPE36799.1 - 0.0012 18.5 5.1 0.0034 17.0 3.5 1.9 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EPE36799.1 - 0.019 14.7 2.0 0.042 13.5 1.4 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EPE36799.1 - 0.033 13.9 5.7 0.075 12.7 4.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.1 EPE36799.1 - 0.38 10.7 7.2 0.27 11.2 3.0 2.2 2 1 1 3 3 3 0 PHD-zinc-finger like domain LPP20 PF02169.11 EPE36799.1 - 0.78 9.8 3.7 2.3 8.3 0.0 2.8 3 0 0 3 3 3 0 LPP20 lipoprotein zf-HC5HC2H PF13771.1 EPE36799.1 - 1.7 8.8 8.3 2.7 8.2 4.7 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain Fringe PF02434.11 EPE36800.1 - 7.6e-12 44.9 0.5 4.6e-10 39.1 0.0 2.6 3 0 0 3 3 3 2 Fringe-like DUF604 PF04646.7 EPE36800.1 - 1.1e-06 28.0 0.0 2.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF604 DUF815 PF05673.8 EPE36800.1 - 0.093 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) BRO1 PF03097.13 EPE36801.1 - 9.3e-121 403.1 1.5 5e-120 400.7 0.0 2.5 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EPE36801.1 - 6.7e-83 278.0 14.4 1.2e-82 277.2 10.0 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CN_hydrolase PF00795.17 EPE36802.1 - 1.8e-21 76.3 0.0 3.9e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EPE36802.1 - 1.3e-14 53.7 0.0 7.6e-14 51.1 0.0 2.2 1 1 0 1 1 1 1 NAD synthase zf-C2H2 PF00096.21 EPE36803.1 - 0.011 16.0 1.2 0.011 16.0 0.9 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPE36803.1 - 0.021 15.1 1.1 0.021 15.1 0.8 3.7 3 2 0 3 3 3 0 Zinc-finger double domain zf-CHCC PF10276.4 EPE36803.1 - 0.11 12.3 5.0 5.1 7.0 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_4 PF13894.1 EPE36803.1 - 0.79 10.2 26.5 0.19 12.1 1.5 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-BED PF02892.10 EPE36803.1 - 5.3 6.8 14.6 0.77 9.5 2.0 3.4 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_jaz PF12171.3 EPE36803.1 - 7.3 6.8 11.0 0.19 11.9 1.5 2.8 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding DSPc PF00782.15 EPE36804.1 - 3.8e-24 84.7 0.0 5.3e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPE36804.1 - 0.063 12.5 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSHCT PF08148.7 EPE36804.1 - 0.09 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain Vfa1 PF08432.5 EPE36805.1 - 1.1e-57 195.0 25.3 1.2e-57 194.8 17.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 EPE36805.1 - 0.0031 15.6 13.8 0.0032 15.5 9.6 1.0 1 0 0 1 1 1 1 CDC45-like protein DDHD PF02862.12 EPE36805.1 - 0.012 15.4 6.3 0.014 15.2 4.4 1.2 1 0 0 1 1 1 0 DDHD domain FLO_LFY PF01698.11 EPE36805.1 - 0.04 12.7 9.7 0.05 12.4 6.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Tim54 PF11711.3 EPE36805.1 - 0.054 12.0 13.0 0.068 11.7 9.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Borrelia_P83 PF05262.6 EPE36805.1 - 0.11 10.7 22.1 0.11 10.7 15.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein U79_P34 PF03064.11 EPE36805.1 - 0.11 12.0 18.4 0.13 11.7 12.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Parvo_coat PF00740.13 EPE36805.1 - 0.14 11.0 4.8 0.14 11.0 3.3 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 RNase_H2-Ydr279 PF09468.5 EPE36805.1 - 0.17 11.0 13.7 0.27 10.3 9.5 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Astro_capsid PF03115.9 EPE36805.1 - 0.2 9.9 7.5 0.23 9.6 5.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Raftlin PF15250.1 EPE36805.1 - 0.23 9.9 10.1 0.28 9.6 7.0 1.1 1 0 0 1 1 1 0 Raftlin SET PF00856.23 EPE36805.1 - 0.24 11.6 3.3 0.3 11.3 2.3 1.2 1 0 0 1 1 1 0 SET domain DUF1510 PF07423.6 EPE36805.1 - 0.28 10.5 25.8 0.41 9.9 17.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CT47 PF15623.1 EPE36805.1 - 0.32 10.6 18.8 0.41 10.3 13.0 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 BTV_NS2 PF04514.7 EPE36805.1 - 0.41 9.4 15.5 0.48 9.2 10.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM60A PF15396.1 EPE36805.1 - 0.58 9.8 11.7 0.94 9.1 8.1 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Ycf1 PF05758.7 EPE36805.1 - 0.59 7.7 19.1 0.71 7.5 13.2 1.1 1 0 0 1 1 1 0 Ycf1 PhyH PF05721.8 EPE36805.1 - 0.65 10.0 4.2 0.83 9.6 2.9 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) DUF262 PF03235.9 EPE36805.1 - 0.84 9.5 9.6 0.99 9.3 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Pox_Ag35 PF03286.9 EPE36805.1 - 0.92 8.9 21.4 1.2 8.5 14.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MIP-T3 PF10243.4 EPE36805.1 - 0.95 7.8 34.1 1.2 7.5 23.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Zip PF02535.17 EPE36805.1 - 1.1 8.1 3.9 1.3 7.9 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0560 PF10577.4 EPE36805.1 - 1.3 7.2 12.5 1.6 6.9 8.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF913 PF06025.7 EPE36805.1 - 1.9 7.1 5.1 2.2 6.9 3.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2201_N PF13203.1 EPE36805.1 - 3.4 6.7 10.6 4.1 6.4 7.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain NPR3 PF03666.8 EPE36805.1 - 4.3 5.7 15.8 5.3 5.4 10.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.2 EPE36805.1 - 5.1 4.6 10.6 5.3 4.5 7.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med12-LCEWAV PF12145.3 EPE36805.1 - 5.3 5.4 13.2 6.8 5.0 9.1 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain TRAP_alpha PF03896.11 EPE36805.1 - 5.8 5.8 12.0 8 5.3 8.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2413 PF10310.4 EPE36805.1 - 6.1 5.5 21.6 8.2 5.1 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Sec62 PF03839.11 EPE36805.1 - 6.3 6.1 22.6 8.2 5.7 15.0 1.8 2 0 0 2 2 2 0 Translocation protein Sec62 Presenilin PF01080.12 EPE36805.1 - 6.5 5.4 5.3 6.8 5.4 3.6 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.7 EPE36805.1 - 6.6 6.5 22.6 8.6 6.1 15.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 EPE36805.1 - 6.8 5.3 24.2 8.2 5.0 16.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RP-C_C PF11800.3 EPE36805.1 - 9 5.9 12.2 12 5.5 8.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Lyase_1 PF00206.15 EPE36806.1 - 2.5e-89 299.5 0.0 3.4e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EPE36806.1 - 6.9e-26 90.1 0.0 1.6e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Ufd2P_core PF10408.4 EPE36807.1 - 2.8e-196 653.5 11.3 3.5e-196 653.2 7.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EPE36807.1 - 1.1e-25 89.3 2.5 2.3e-25 88.3 1.2 2.0 2 0 0 2 2 2 1 U-box domain DnaJ PF00226.26 EPE36808.1 - 1.1e-21 76.3 0.1 2.1e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EPE36808.1 - 8.4e-19 67.8 0.4 1.5e-18 66.9 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DUF2416 PF10315.4 EPE36809.1 - 5.5e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2416) Ima1_N PF09779.4 EPE36810.1 - 9.6e-27 94.0 0.5 1.7e-26 93.2 0.3 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain DUF4531 PF15041.1 EPE36810.1 - 0.027 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) Alg14 PF08660.6 EPE36811.1 - 2e-51 174.3 0.0 4.2e-51 173.3 0.0 1.5 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TAS2R PF05296.8 EPE36811.1 - 0.00043 19.2 0.8 0.00043 19.2 0.6 1.6 2 0 0 2 2 2 1 Mammalian taste receptor protein (TAS2R) MRP-S25 PF13741.1 EPE36812.1 - 4.2e-72 242.3 4.3 2.4e-70 236.6 3.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EPE36812.1 - 0.034 14.0 1.6 0.24 11.2 1.1 2.1 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 PPR_2 PF13041.1 EPE36813.1 - 3.4e-15 55.7 4.8 3.1e-06 27.0 0.0 5.5 4 2 2 6 6 6 5 PPR repeat family PPR PF01535.15 EPE36813.1 - 8.7e-10 37.9 9.0 2.2e-05 24.1 0.1 5.5 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.1 EPE36813.1 - 1.2e-09 37.6 3.2 0.006 16.7 0.0 5.7 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EPE36813.1 - 6.2e-05 22.3 2.7 0.0024 17.3 0.0 3.5 3 1 0 3 3 3 1 PPR repeat Lentiviral_Tat PF02998.9 EPE36813.1 - 0.55 10.0 3.8 1 9.2 0.1 2.8 2 0 0 2 2 2 0 Lentiviral Tat protein PNK3P PF08645.6 EPE36814.1 - 6.7e-54 181.6 0.0 9.8e-54 181.0 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EPE36814.1 - 1.9e-28 99.1 0.1 1.1e-27 96.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPE36814.1 - 0.0065 15.5 0.2 0.12 11.4 0.0 2.1 1 1 1 2 2 2 1 Zeta toxin KTI12 PF08433.5 EPE36814.1 - 0.0099 15.1 2.7 0.54 9.4 0.2 2.3 1 1 1 2 2 2 2 Chromatin associated protein KTI12 AAA_25 PF13481.1 EPE36814.1 - 0.16 11.3 0.1 0.82 9.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 EPE36816.1 - 8.7e-07 28.3 0.0 0.023 13.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Rtt106 PF08512.7 EPE36817.1 - 9.6e-25 86.4 0.0 1.7e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like MNSV_P7B PF06692.6 EPE36818.1 - 0.1 12.3 0.2 0.29 10.9 0.1 1.8 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein DUF202 PF02656.10 EPE36818.1 - 0.63 10.3 4.1 5.7 7.2 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) CHD5 PF04420.9 EPE36819.1 - 9.6e-54 181.3 0.5 1.2e-53 181.0 0.3 1.1 1 0 0 1 1 1 1 CHD5-like protein Flu_NS2 PF00601.14 EPE36819.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) MHC_II_alpha PF00993.15 EPE36819.1 - 0.13 11.9 0.0 0.34 10.4 0.0 1.7 1 1 0 1 1 1 0 Class II histocompatibility antigen, alpha domain PPTA PF01239.17 EPE36820.1 - 9.1e-08 31.1 10.2 5.5e-05 22.3 0.2 3.8 4 1 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat G_glu_transpept PF01019.16 EPE36820.1 - 0.097 11.1 0.1 0.13 10.7 0.1 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Ecm33 PF12454.3 EPE36821.1 - 1.7e-10 40.6 4.2 5e-10 39.0 2.1 2.6 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EPE36821.1 - 1.1e-07 31.7 0.2 0.014 15.3 0.0 3.9 1 1 3 4 4 4 2 Receptor L domain H_lectin PF09458.5 EPE36821.1 - 1.5 8.5 5.3 2.4 7.8 0.6 2.9 3 0 0 3 3 3 0 H-type lectin domain AcetylCoA_hydro PF02550.10 EPE36822.1 - 1.6e-47 161.8 0.0 2.4e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EPE36822.1 - 1.4e-39 135.2 0.0 2.3e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 EPE36822.1 - 0.021 13.9 0.0 0.061 12.5 0.0 1.7 2 0 0 2 2 2 0 Coenzyme A transferase Peptidase_S55 PF05580.7 EPE36822.1 - 0.096 12.1 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 SpoIVB peptidase S55 Ndc1_Nup PF09531.5 EPE36823.1 - 1.4e-143 479.5 0.0 1.5e-143 479.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 EPE36824.1 - 5.1e-25 87.4 9.6 6.1e-25 87.2 3.2 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EPE36824.1 - 3.1e-19 68.4 1.5 8.7e-19 66.9 1.0 1.8 1 0 0 1 1 1 1 SNARE domain MCPsignal PF00015.16 EPE36824.1 - 0.0083 15.6 7.6 0.19 11.2 1.8 2.2 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Vac_Fusion PF02346.11 EPE36824.1 - 0.035 13.5 0.7 0.16 11.4 0.1 2.4 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Syntaxin PF00804.20 EPE36824.1 - 0.041 14.0 10.8 0.45 10.7 6.9 2.8 1 1 1 2 2 2 0 Syntaxin DUF651 PF04895.7 EPE36824.1 - 0.15 11.6 0.1 0.15 11.6 0.1 2.4 3 0 0 3 3 3 0 Archaeal protein of unknown function (DUF651) DUF883 PF05957.8 EPE36824.1 - 0.72 10.2 9.5 0.52 10.7 0.1 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.8 EPE36824.1 - 4.7 6.1 6.1 21 4.0 4.2 1.9 1 1 0 1 1 1 0 TMPIT-like protein Tweety PF04906.8 EPE36824.1 - 5 5.4 6.4 11 4.2 0.8 2.8 2 2 0 2 2 2 0 Tweety GRAB PF10375.4 EPE36825.1 - 7.2e-09 34.9 0.2 1.4e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Tropomyosin PF00261.15 EPE36825.1 - 0.00015 20.9 41.5 0.00015 20.9 28.8 2.8 1 1 1 2 2 2 1 Tropomyosin Reo_sigmaC PF04582.7 EPE36825.1 - 0.019 14.1 19.4 0.12 11.5 0.1 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 EPE36825.1 - 0.11 11.8 56.0 2.1 7.7 8.9 3.2 1 1 1 2 2 2 0 Intermediate filament protein AAA_27 PF13514.1 EPE36825.1 - 0.16 9.6 51.7 0.7 7.4 22.2 2.1 1 1 1 2 2 2 0 AAA domain DUF3584 PF12128.3 EPE36825.1 - 0.45 7.7 56.6 0.09 10.0 25.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1722 PF08349.6 EPE36825.1 - 1.5 8.7 6.4 0.57 10.0 0.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) DUF4618 PF15397.1 EPE36825.1 - 2.4 7.4 43.0 0.33 10.2 4.6 4.2 1 1 2 4 4 4 0 Domain of unknown function (DUF4618) CENP-F_leu_zip PF10473.4 EPE36825.1 - 2.6 7.8 60.3 0.22 11.3 15.7 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EPE36825.1 - 3.5 7.1 70.9 0.83 9.2 14.0 3.4 1 1 2 3 3 3 0 IncA protein HR1 PF02185.11 EPE36825.1 - 6.9 6.4 33.7 2 8.2 1.2 4.8 3 2 1 4 4 4 0 Hr1 repeat Catalase PF00199.14 EPE36826.1 - 7.8e-12 44.5 0.3 6.7e-06 25.0 0.0 2.3 1 1 0 2 2 2 2 Catalase MHYT PF03707.11 EPE36828.1 - 0.004 17.2 3.2 0.004 17.2 2.2 3.9 4 0 0 4 4 4 2 Bacterial signalling protein N terminal repeat G-patch PF01585.18 EPE36829.1 - 1.8e-12 46.8 2.1 3.3e-12 45.9 1.4 1.4 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EPE36829.1 - 2e-07 30.7 0.0 3.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPE36829.1 - 3.2e-05 23.4 0.0 6.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE36829.1 - 0.0006 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 4HBT_3 PF13622.1 EPE36829.1 - 9 5.9 12.5 1.9 8.2 0.6 2.2 2 0 0 2 2 2 0 Thioesterase-like superfamily AMP-binding PF00501.23 EPE36830.1 - 2.1e-84 283.3 0.0 2.6e-84 283.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPE36830.1 - 1.5e-16 61.0 0.1 1.8e-15 57.6 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EPE36830.1 - 0.002 16.7 0.0 0.015 13.8 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter zf-RING_2 PF13639.1 EPE36831.1 - 2.5e-07 30.3 6.0 5.8e-07 29.2 4.2 1.6 1 0 0 1 1 1 1 Ring finger domain SWIM PF04434.12 EPE36831.1 - 2e-05 23.9 0.2 4.3e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-Apc11 PF12861.2 EPE36831.1 - 0.00018 21.2 2.0 0.00018 21.2 1.4 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EPE36831.1 - 0.00069 19.6 2.8 0.00069 19.6 1.9 1.6 2 0 0 2 2 1 1 RING-H2 zinc finger Prok-RING_1 PF14446.1 EPE36831.1 - 0.00099 18.7 2.9 0.00099 18.7 2.0 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EPE36831.1 - 0.003 17.5 4.9 0.003 17.5 3.4 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_4 PF14570.1 EPE36831.1 - 0.045 13.3 7.2 0.1 12.1 5.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EPE36831.1 - 0.08 12.9 7.1 0.21 11.6 4.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EPE36831.1 - 0.11 12.2 7.0 0.23 11.1 4.8 1.6 1 0 0 1 1 1 0 PHD-finger Tom37_C PF11801.3 EPE36831.1 - 0.44 10.4 2.4 0.7 9.7 1.6 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Baculo_IE-1 PF05290.6 EPE36831.1 - 0.69 9.6 4.0 2.7 7.7 2.8 1.9 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF3020 PF11223.3 EPE36831.1 - 1.2 9.6 11.2 2.5 8.5 7.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3020) zf-C3HC4_3 PF13920.1 EPE36831.1 - 1.5 8.5 6.2 4.5 7.0 4.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2408 PF10303.4 EPE36833.1 - 9.2e-41 139.0 8.1 1.4e-27 96.4 0.3 5.1 2 2 3 5 5 5 3 Protein of unknown function (DUF2408) Pox_J1 PF03338.10 EPE36833.1 - 0.00046 19.9 1.7 0.73 9.5 0.1 3.9 4 0 0 4 4 4 2 Poxvirus J1 protein Laminin_II PF06009.7 EPE36833.1 - 0.06 13.1 8.2 0.41 10.3 0.1 2.8 2 1 1 3 3 3 0 Laminin Domain II Nup54 PF13874.1 EPE36833.1 - 0.34 10.5 2.9 0.86 9.2 1.8 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Ribosomal_60s PF00428.14 EPE36834.1 - 1.1e-25 89.8 9.1 1.3e-25 89.5 6.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein YCII PF03795.9 EPE36835.1 - 2.5e-06 27.5 0.0 4.1e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 YCII-related domain HMG_box PF00505.14 EPE36836.1 - 2.9e-13 49.8 0.2 5.7e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPE36836.1 - 2.1e-09 37.6 0.3 4.6e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain Methyltransf_1N PF02870.10 EPE36836.1 - 0.049 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain SLT PF01464.15 EPE36836.1 - 0.066 12.7 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain Cut8_C PF08559.5 EPE36838.1 - 1.3e-49 167.7 0.0 1.8e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EPE36838.1 - 1.4e-15 56.7 0.5 2.7e-15 55.8 0.4 1.5 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EPE36838.1 - 1.8e-09 37.4 1.1 1.8e-09 37.4 0.8 1.8 2 0 0 2 2 2 1 Cut8 proteasome-binding domain OTCace_N PF02729.16 EPE36839.1 - 4.1e-42 143.1 0.6 7.1e-42 142.4 0.4 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EPE36839.1 - 9.7e-41 139.2 0.0 1.6e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Porin_3 PF01459.17 EPE36840.1 - 1.4e-58 198.3 10.5 2.8e-58 197.3 7.3 1.5 1 1 0 1 1 1 1 Eukaryotic porin zf-CCHC PF00098.18 EPE36841.1 - 7.8 6.6 9.2 0.9 9.5 3.1 2.0 2 0 0 2 2 2 0 Zinc knuckle Pex19 PF04614.7 EPE36843.1 - 1.1e-71 241.3 14.4 1.5e-71 240.9 10.0 1.1 1 0 0 1 1 1 1 Pex19 protein family FliE PF02049.13 EPE36843.1 - 0.015 15.3 3.2 0.015 15.3 2.2 3.3 1 1 3 4 4 4 0 Flagellar hook-basal body complex protein FliE UQ_con PF00179.21 EPE36844.1 - 9.7e-49 164.4 0.1 1.1e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPE36844.1 - 0.0014 18.4 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPE36844.1 - 0.087 12.7 0.7 0.12 12.2 0.5 1.6 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.16 EPE36845.1 - 1.6e-68 230.9 0.1 2.2e-68 230.4 0.1 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EPE36845.1 - 9.2e-37 125.5 0.0 1.7e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EPE36845.1 - 2.4e-29 101.9 0.0 7.8e-29 100.3 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EPE36845.1 - 6.8e-09 35.2 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EPE36845.1 - 4.1e-05 22.5 0.1 0.0006 18.7 0.0 2.1 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 EPE36845.1 - 0.0043 15.8 0.1 0.3 9.7 0.0 2.7 1 1 2 3 3 3 1 Glutamine amidotransferases class-II BRX_N PF13713.1 EPE36845.1 - 0.088 12.2 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain DUF3398 PF11878.3 EPE36846.1 - 0.16 11.8 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) Peptidase_M24 PF00557.19 EPE36847.1 - 2.3e-44 151.4 0.0 3e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.7 EPE36847.1 - 0.72 9.6 5.6 1.4 8.6 3.9 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Cnd2 PF05786.9 EPE36847.1 - 2.8 6.3 8.7 4.4 5.6 6.0 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 DnaJ PF00226.26 EPE36848.1 - 1.1e-19 69.8 0.3 1.6e-19 69.3 0.2 1.2 1 0 0 1 1 1 1 DnaJ domain adh_short PF00106.20 EPE36849.1 - 1.3e-17 64.2 0.8 4.2e-16 59.3 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE36849.1 - 1.1e-14 54.8 0.2 4.2e-14 52.8 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE36849.1 - 2.7e-09 36.9 0.1 4.6e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EPE36849.1 - 0.0025 17.8 0.2 0.005 16.9 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase PSP PF04046.11 EPE36849.1 - 0.021 14.2 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 PSP 3Beta_HSD PF01073.14 EPE36849.1 - 0.1 11.2 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EPE36849.1 - 0.12 11.2 0.1 0.22 10.3 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EPE36849.1 - 0.13 11.2 0.3 0.23 10.4 0.2 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase DUF3611 PF12263.3 EPE36850.1 - 0.00012 21.5 0.1 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) SKG6 PF08693.5 EPE36850.1 - 0.00019 20.6 0.0 0.00037 19.7 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EPE36850.1 - 0.026 12.7 0.0 0.027 12.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VSP PF03302.8 EPE36850.1 - 0.076 11.6 0.1 0.096 11.3 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF3482 PF11981.3 EPE36850.1 - 0.33 10.1 3.3 0.48 9.6 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) AA_permease PF00324.16 EPE36851.1 - 1.5e-117 392.8 44.4 1.8e-117 392.6 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPE36851.1 - 1.8e-35 122.3 47.0 2.2e-35 122.0 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 EPE36851.1 - 0.028 14.5 0.6 0.028 14.5 0.4 5.3 6 1 1 7 7 7 0 PrgI family protein DUF3328 PF11807.3 EPE36852.1 - 1.2e-29 103.5 0.3 1.6e-29 103.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) GHMP_kinases_N PF00288.21 EPE36853.1 - 5.7e-12 45.5 1.8 3e-11 43.1 0.4 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPE36853.1 - 0.0071 16.5 0.0 0.049 13.8 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal DUF3248 PF11609.3 EPE36853.1 - 0.027 14.1 0.9 0.22 11.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3248) Cyto_heme_lyase PF01265.12 EPE36854.1 - 5.4e-85 285.1 0.0 6e-85 284.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF647 PF04884.9 EPE36855.1 - 2.4e-103 344.7 0.3 3e-103 344.3 0.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF204 PF02659.10 EPE36855.1 - 0.48 10.5 3.5 0.31 11.2 0.6 2.1 3 0 0 3 3 3 0 Domain of unknown function DUF DENN PF02141.16 EPE36856.1 - 5.3e-59 199.0 0.0 8.6e-59 198.3 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EPE36856.1 - 2e-18 66.2 0.4 4.6e-18 65.0 0.3 1.7 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EPE36856.1 - 7.8e-16 57.8 0.0 1.8e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 uDENN domain FDF PF09532.5 EPE36856.1 - 0.0057 17.1 1.4 0.032 14.7 0.0 2.5 2 0 0 2 2 2 1 FDF domain PHD PF00628.24 EPE36856.1 - 0.011 15.3 6.9 0.024 14.3 4.8 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 EPE36856.1 - 0.036 13.7 7.2 0.062 13.0 5.0 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SPA PF08616.5 EPE36856.1 - 0.18 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis C1_3 PF07649.7 EPE36856.1 - 2.6 8.1 7.6 5.7 7.0 5.3 1.6 1 0 0 1 1 1 0 C1-like domain Prok-RING_1 PF14446.1 EPE36856.1 - 3.6 7.3 10.4 0.94 9.2 4.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_2 PF03107.11 EPE36856.1 - 9.6 6.4 8.3 20 5.3 5.8 1.6 1 0 0 1 1 1 0 C1 domain rRNA_proc-arch PF13234.1 EPE36857.1 - 1.3e-100 335.9 0.3 4e-100 334.4 0.0 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EPE36857.1 - 2.4e-61 206.1 1.9 4.6e-61 205.1 1.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EPE36857.1 - 5.2e-22 78.1 0.1 1.3e-21 76.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE36857.1 - 1.4e-05 24.9 0.0 3.2e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPE36857.1 - 0.002 17.9 0.3 0.05 13.4 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Prp19 PF08606.6 EPE36857.1 - 0.0049 16.5 1.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 2 Prp19/Pso4-like T2SE PF00437.15 EPE36857.1 - 0.025 13.4 0.0 0.054 12.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein COX7C PF02935.11 EPE36858.1 - 8.6e-17 60.6 0.8 1e-16 60.4 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Med18 PF09637.5 EPE36859.1 - 1.8e-48 165.2 0.0 2.1e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein HsbA PF12296.3 EPE36860.1 - 4.7e-37 126.6 12.7 6.5e-37 126.1 8.8 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Lectin_N PF03954.9 EPE36860.1 - 0.025 13.9 1.3 0.37 10.1 0.7 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF3616 PF12275.3 EPE36860.1 - 0.054 12.4 0.1 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) CRIC_ras_sig PF10534.4 EPE36860.1 - 0.079 13.0 1.8 0.29 11.1 0.2 2.1 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras DUF1451 PF07295.6 EPE36860.1 - 0.09 12.5 0.3 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DUF1664 PF07889.7 EPE36860.1 - 0.095 12.5 0.4 4.6 7.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HTH_Tnp_Mu_1 PF02316.11 EPE36860.1 - 0.12 12.1 1.2 0.39 10.4 0.4 2.0 1 1 1 2 2 2 0 Mu DNA-binding domain Baculo_PEP_C PF04513.7 EPE36860.1 - 0.17 11.7 9.6 0.73 9.6 1.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FadA PF09403.5 EPE36860.1 - 0.23 11.4 1.8 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Adhesion protein FadA Phage_Coat_B PF05356.6 EPE36860.1 - 0.42 10.3 3.1 7.6 6.3 0.1 2.7 1 1 1 2 2 2 0 Phage Coat protein B DUF4355 PF14265.1 EPE36860.1 - 0.49 10.3 6.9 0.45 10.4 0.6 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4355) LPP PF04728.8 EPE36860.1 - 9.7 6.0 15.5 0.68 9.7 0.7 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF2638 PF10937.3 EPE36861.1 - 1.4e-33 116.2 0.8 2.7e-33 115.3 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) GMC_oxred_C PF05199.8 EPE36862.1 - 9.7e-33 113.4 0.0 1.9e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EPE36862.1 - 1.3e-32 113.1 0.0 6.6e-25 87.8 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.19 EPE36862.1 - 2.2e-06 26.8 0.5 0.013 14.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE36862.1 - 8.4e-05 21.5 0.2 0.0047 15.8 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EPE36862.1 - 0.0076 16.1 0.0 0.87 9.4 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPE36862.1 - 0.0077 16.3 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE36862.1 - 0.02 14.9 0.5 0.041 13.8 0.3 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HD PF01966.17 EPE36863.1 - 3.1e-08 33.6 0.0 4.3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 HD domain Pyr_redox_3 PF13738.1 EPE36864.1 - 5.5e-22 78.8 0.0 1e-21 77.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPE36864.1 - 1.3e-12 46.7 0.0 4.7e-09 34.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPE36864.1 - 1.2e-11 44.1 0.1 7.1e-11 41.5 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPE36864.1 - 3.9e-06 26.8 0.0 8.2e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE36864.1 - 5.8e-06 26.2 0.1 3.5e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPE36864.1 - 6.1e-06 25.3 0.0 0.52 9.1 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EPE36864.1 - 0.0012 17.4 0.1 0.88 7.9 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 EPE36864.1 - 0.0012 17.9 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EPE36864.1 - 0.049 13.3 0.4 0.83 9.4 0.1 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EPE36864.1 - 0.073 13.4 0.1 20 5.6 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPE36864.1 - 0.18 10.8 0.1 7 5.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Peptidase_M14 PF00246.19 EPE36865.1 - 2.5e-44 151.9 0.2 3.5e-44 151.5 0.2 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF1798 PF08807.5 EPE36866.1 - 0.0047 16.6 0.6 0.0069 16.0 0.4 1.3 1 0 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) DUF2654 PF10849.3 EPE36866.1 - 0.096 12.4 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) PAT1 PF09770.4 EPE36867.1 - 2 6.5 18.9 2.3 6.3 13.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Actin PF00022.14 EPE36869.1 - 1.2e-05 23.8 0.1 1.9e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Actin Phage_fiber_2 PF03406.8 EPE36871.1 - 2 8.1 4.8 5.1 6.8 3.3 1.7 1 0 0 1 1 1 0 Phage tail fibre repeat zf-C4H2 PF10146.4 EPE36876.1 - 0.17 11.8 1.6 0.22 11.5 1.1 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein ALS_ss_C PF10369.4 EPE36877.1 - 1.5e-18 66.2 0.0 1.5e-17 63.0 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EPE36877.1 - 2.2e-12 46.1 0.1 4.5e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EPE36877.1 - 2.1e-09 37.0 0.0 3.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EPE36877.1 - 0.14 11.8 0.1 20 4.9 0.0 2.6 2 0 0 2 2 2 0 ACT domain KH_1 PF00013.24 EPE36878.1 - 5.5e-11 41.9 0.0 1.5e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EPE36878.1 - 1.2e-05 24.8 3.4 0.00056 19.5 0.1 3.0 3 0 0 3 3 3 2 KH domain SET PF00856.23 EPE36879.1 - 7.9e-14 52.2 0.1 2.1e-12 47.6 0.0 2.5 2 1 0 2 2 2 1 SET domain DUF974 PF06159.8 EPE36880.1 - 2.3e-75 253.2 0.0 1.2e-74 250.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF974) LEA_2 PF03168.8 EPE36881.1 - 0.00017 21.8 4.3 2.2 8.7 0.0 5.4 4 1 0 5 5 5 2 Late embryogenesis abundant protein DUF3712 PF12505.3 EPE36881.1 - 0.00078 19.4 0.1 0.0041 17.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) SKG6 PF08693.5 EPE36881.1 - 0.053 12.8 0.2 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AalphaY_MDB PF04611.7 EPE36885.1 - 0.015 15.1 0.1 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region RGS PF00615.14 EPE36887.1 - 1.7e-10 40.9 0.0 2.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Aa_trans PF01490.13 EPE36889.1 - 1.3e-19 70.0 34.5 1.7e-19 69.5 23.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IBV_3C PF03620.8 EPE36889.1 - 0.075 12.9 5.9 0.17 11.7 0.3 3.0 2 0 0 2 2 2 0 IBV 3C protein Arch_ATPase PF01637.13 EPE36890.1 - 2.1e-07 30.8 0.0 4.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EPE36890.1 - 5.4e-07 29.4 0.0 1.5e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.2 EPE36890.1 - 6.3e-06 26.4 0.0 5.8e-05 23.3 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPE36890.1 - 0.00014 21.4 0.4 3.3 7.7 0.1 4.1 3 1 0 3 3 3 1 Ankyrin repeat AAA PF00004.24 EPE36890.1 - 0.00091 19.4 0.1 0.012 15.8 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPE36890.1 - 0.0012 19.0 0.0 0.006 16.7 0.0 2.4 1 0 0 1 1 1 1 AAA domain YolD PF08863.5 EPE36890.1 - 0.0045 16.8 0.1 0.058 13.2 0.1 2.5 2 0 0 2 2 2 1 YolD-like protein AAA_17 PF13207.1 EPE36890.1 - 0.0047 17.7 0.0 0.017 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EPE36890.1 - 0.015 14.7 0.1 0.046 13.1 0.1 1.8 1 0 0 1 1 1 0 AAA-like domain DUF676 PF05057.9 EPE36890.1 - 0.021 14.1 0.0 0.1 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) AAA_19 PF13245.1 EPE36890.1 - 0.043 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EPE36890.1 - 0.08 12.8 0.0 0.39 10.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPE36890.1 - 0.091 12.2 0.1 0.28 10.7 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EPE36890.1 - 0.1 12.4 0.0 0.36 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EPE36890.1 - 0.11 12.8 0.1 0.39 10.9 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPE36890.1 - 0.13 12.5 0.1 0.43 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPE36890.1 - 0.17 12.0 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase MIP PF00230.15 EPE36892.1 - 8.1e-47 159.5 21.7 9.7e-47 159.3 15.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF788 PF05620.6 EPE36892.1 - 0.08 12.7 1.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Steroid_dh PF02544.11 EPE36893.1 - 3.3e-19 69.1 0.2 2.8e-18 66.1 0.0 2.3 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EPE36893.1 - 5.1e-05 22.6 0.1 8.5e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) MutS_III PF05192.13 EPE36894.1 - 0.01 15.6 0.1 0.012 15.4 0.1 1.3 1 1 0 1 1 1 0 MutS domain III CTP_transf_2 PF01467.21 EPE36894.1 - 0.011 15.7 0.0 0.27 11.2 0.0 2.8 2 1 0 3 3 3 0 Cytidylyltransferase Citrate_ly_lig PF08218.6 EPE36894.1 - 0.033 13.6 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain T4_Gp59_C PF08994.5 EPE36895.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term ATP-grasp_4 PF13535.1 EPE36896.1 - 1.3e-25 90.1 0.1 2.7e-22 79.4 0.0 3.2 3 1 0 4 4 4 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EPE36896.1 - 1.4e-08 34.3 0.0 3.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EPE36896.1 - 1.5e-07 30.4 0.0 0.0051 15.5 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EPE36896.1 - 4.5e-06 26.6 0.0 2.6e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EPE36896.1 - 1.6e-05 24.5 0.0 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 EPE36896.1 - 0.00023 20.5 0.0 0.00055 19.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 EPE36896.1 - 0.13 11.5 0.0 0.71 9.1 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.6 EPE36896.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain WD40 PF00400.27 EPE36897.1 - 1.3e-50 167.5 18.9 1.2e-11 44.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EPE36897.1 - 0.03 13.8 0.2 14 5.2 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain adh_short PF00106.20 EPE36899.1 - 7.8e-17 61.6 0.3 1.2e-16 61.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE36899.1 - 1.4e-05 24.7 0.1 1.9e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 EPE36899.1 - 0.048 13.9 0.0 0.58 10.4 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain AIRC PF00731.15 EPE36899.1 - 0.067 12.4 0.1 2.5 7.3 0.0 2.7 2 1 1 3 3 3 0 AIR carboxylase DUF1776 PF08643.5 EPE36899.1 - 0.085 11.9 0.0 2.3 7.2 0.0 2.1 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Endonuc-FokI_C PF09254.6 EPE36900.1 - 0.15 11.1 0.7 0.24 10.4 0.5 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Glyco_hydro_32N PF00251.15 EPE36901.1 - 0.00019 20.8 0.1 0.00069 19.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.9 EPE36901.1 - 0.0025 16.9 2.3 0.0043 16.1 1.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Exo_endo_phos_2 PF14529.1 EPE36901.1 - 0.068 12.7 0.3 1.5 8.4 0.2 2.3 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase AAA PF00004.24 EPE36902.1 - 3e-06 27.4 0.0 5.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 EPE36902.1 - 0.0057 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Torsin AAA_19 PF13245.1 EPE36902.1 - 0.033 13.9 0.1 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EPE36902.1 - 0.049 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FAM104 PF15434.1 EPE36902.1 - 0.14 12.3 0.9 0.58 10.3 0.6 2.0 1 1 0 1 1 1 0 Family 104 DUF2981 PF11200.3 EPE36903.1 - 0.098 11.7 5.2 0.046 12.7 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2981) Pox_A51 PF04948.8 EPE36905.1 - 0.038 12.6 0.1 0.048 12.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A51 protein MARVEL PF01284.18 EPE36906.1 - 3.4e-06 26.9 10.2 2.4e-05 24.1 6.1 2.0 1 1 1 2 2 2 2 Membrane-associating domain DUF3112 PF11309.3 EPE36906.1 - 0.009 15.8 0.2 0.011 15.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) MIG-14_Wnt-bd PF06664.7 EPE36906.1 - 0.052 12.3 0.2 0.06 12.1 0.1 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion PRA1 PF03208.14 EPE36906.1 - 5.2 6.3 7.5 0.99 8.7 2.3 1.9 2 1 0 2 2 2 0 PRA1 family protein WLM PF08325.5 EPE36908.1 - 3e-45 154.4 0.0 4.4e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EPE36908.1 - 0.00013 21.8 0.4 0.00037 20.3 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 EPE36908.1 - 0.00031 20.4 0.8 0.00043 19.9 0.1 1.5 2 0 0 2 2 2 1 SprT-like family ubiquitin PF00240.18 EPE36908.1 - 0.018 14.4 0.0 0.052 12.9 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family YukD PF08817.5 EPE36908.1 - 0.026 15.0 0.1 0.086 13.4 0.0 1.9 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Reprolysin_5 PF13688.1 EPE36908.1 - 0.059 13.2 0.4 0.13 12.2 0.2 1.6 1 1 1 2 2 2 0 Metallo-peptidase family M12 Peptidase_MA_2 PF13485.1 EPE36908.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily ER_lumen_recept PF00810.13 EPE36909.1 - 1.4e-55 187.8 10.2 2.3e-55 187.1 7.1 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EPE36909.1 - 0.11 12.1 16.2 0.24 10.9 0.2 4.3 5 0 0 5 5 5 0 PQ loop repeat Molybdopterin PF00384.17 EPE36910.1 - 1.5e-74 251.3 0.0 2.1e-72 244.2 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EPE36910.1 - 2.4e-19 68.9 0.2 7.6e-19 67.3 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EPE36910.1 - 4.1e-19 67.5 0.2 1.3e-18 65.8 0.1 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EPE36910.1 - 3.3e-14 52.7 0.0 8.3e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EPE36910.1 - 2.3e-08 33.6 0.6 2.3e-08 33.6 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EPE36910.1 - 0.0022 17.7 0.0 0.025 14.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DDOST_48kD PF03345.9 EPE36913.1 - 1.3e-166 554.3 0.0 1.5e-166 554.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta RTA1 PF04479.8 EPE36914.1 - 4.1e-49 167.1 1.6 5.8e-49 166.6 1.1 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3754 PF12576.3 EPE36914.1 - 0.16 11.6 0.2 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Amidohydro_4 PF13147.1 EPE36915.1 - 1.8e-20 74.1 4.7 3.9e-09 36.9 0.0 3.4 3 0 0 3 3 3 3 Amidohydrolase Amidohydro_1 PF01979.15 EPE36915.1 - 2.3e-11 43.9 5.0 2e-10 40.8 0.2 2.6 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EPE36915.1 - 4.9e-09 35.8 1.7 1.2e-06 28.2 0.1 3.0 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_3 PF07969.6 EPE36915.1 - 8.3e-08 31.8 2.4 0.00037 19.8 0.1 3.2 3 0 0 3 3 3 2 Amidohydrolase family MGC-24 PF05283.6 EPE36916.1 - 0.0052 16.5 1.3 0.012 15.4 0.9 1.5 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Asp PF00026.18 EPE36916.1 - 0.0093 15.2 0.2 0.0093 15.2 0.1 1.8 3 0 0 3 3 3 1 Eukaryotic aspartyl protease DUF4366 PF14283.1 EPE36916.1 - 0.019 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TMEM51 PF15345.1 EPE36916.1 - 0.06 13.0 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Rifin_STEVOR PF02009.11 EPE36916.1 - 0.098 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family peroxidase PF00141.18 EPE36918.1 - 1.6e-27 96.4 0.1 2.3e-27 95.9 0.1 1.1 1 0 0 1 1 1 1 Peroxidase MFS_1 PF07690.11 EPE36920.1 - 6.7e-30 103.9 28.9 6.7e-30 103.9 20.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S8 PF00082.17 EPE36922.1 - 4.7e-52 176.8 15.8 6.1e-52 176.5 11.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EPE36922.1 - 8e-23 80.8 1.2 2.1e-22 79.5 0.8 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.13 EPE36923.1 - 5.5e-109 363.7 0.2 1.2e-108 362.6 0.1 1.6 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EPE36923.1 - 1.2e-11 43.9 1.9 3.1e-05 23.6 0.0 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat Laminin_G_3 PF13385.1 EPE36923.1 - 1.6e-11 44.7 0.1 3.5e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 EPE36923.1 - 2.1e-10 40.3 0.0 6.3e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH APH PF01636.18 EPE36924.1 - 4e-11 43.0 0.0 6.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPE36924.1 - 1.1e-06 28.3 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EPE36924.1 - 0.09 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family YjeF_N PF03853.10 EPE36925.1 - 2e-36 125.1 0.0 2.4e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DUF429 PF04250.8 EPE36925.1 - 0.14 11.3 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF429) Ribosomal_S16 PF00886.14 EPE36926.1 - 1.5e-26 91.8 0.1 2e-26 91.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.13 EPE36927.1 - 2.1e-93 313.0 17.9 3.5e-93 312.3 12.4 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EPE36927.1 - 2.9e-09 36.2 21.0 5.8e-09 35.2 14.6 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family YfhO PF09586.5 EPE36927.1 - 0.052 11.5 3.6 0.085 10.8 2.5 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ORMDL PF04061.9 EPE36927.1 - 0.2 11.1 4.0 0.95 9.0 2.8 2.1 1 1 0 1 1 1 0 ORMDL family MutS_III PF05192.13 EPE36928.1 - 0.024 14.4 0.9 0.043 13.5 0.7 1.3 1 1 0 1 1 1 0 MutS domain III TMEM141 PF15110.1 EPE36928.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 TMEM141 protein family Isochorismatase PF00857.15 EPE36930.1 - 4.1e-20 72.4 0.0 7.2e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family adh_short_C2 PF13561.1 EPE36931.1 - 3.4e-28 99.0 0.1 4.5e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE36931.1 - 1.6e-23 83.4 0.5 2.2e-23 83.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE36931.1 - 1.2e-13 51.1 0.2 1.8e-13 50.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPE36931.1 - 0.0017 17.8 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EPE36931.1 - 0.003 17.2 0.1 0.028 14.0 0.2 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1752 PF08550.5 EPE36934.1 - 3.8e-09 35.9 4.4 6.7e-09 35.1 3.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DLIC PF05783.6 EPE36935.1 - 1.5e-40 139.3 1.0 1.8e-37 129.1 0.0 3.0 2 1 1 3 3 3 3 Dynein light intermediate chain (DLIC) RRM_1 PF00076.17 EPE36936.1 - 3.5e-20 71.4 0.0 9.9e-20 69.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE36936.1 - 2.3e-14 53.1 0.0 4e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE36936.1 - 2.1e-08 33.8 0.0 3.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vpu PF00558.14 EPE36936.1 - 1.1 8.8 3.0 0.69 9.5 0.1 2.1 2 0 0 2 2 2 0 Vpu protein Pex14_N PF04695.8 EPE36936.1 - 1.8 8.6 5.2 7.8 6.5 3.5 2.0 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.27 EPE36937.1 - 2.7e-09 36.5 0.8 0.0026 17.5 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Septin PF00735.13 EPE36938.1 - 2e-106 355.1 0.1 4.9e-106 353.8 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EPE36938.1 - 0.0002 21.2 0.0 0.0005 20.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPE36938.1 - 0.0025 17.0 0.1 0.0063 15.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EPE36938.1 - 0.0053 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPE36938.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EPE36938.1 - 0.02 14.3 0.0 0.57 9.5 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 EPE36938.1 - 0.022 15.2 0.3 0.064 13.7 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EPE36938.1 - 0.041 13.7 7.6 1.5 8.6 0.1 3.0 3 0 0 3 3 3 0 Dynamin family AIG1 PF04548.11 EPE36938.1 - 0.098 11.7 0.0 0.098 11.7 0.0 1.6 2 0 0 2 2 2 0 AIG1 family GLE1 PF07817.8 EPE36938.1 - 0.2 10.5 1.7 0.31 9.9 1.2 1.2 1 0 0 1 1 1 0 GLE1-like protein AAA_17 PF13207.1 EPE36938.1 - 0.22 12.3 0.2 0.22 12.3 0.1 2.8 2 2 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EPE36938.1 - 5.2 6.4 5.9 0.35 10.3 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family OmpH PF03938.9 EPE36938.1 - 6.8 6.6 9.1 12 5.8 6.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CPSase_L_D2 PF02786.12 EPE36940.1 - 1e-72 243.8 0.0 1.5e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EPE36940.1 - 5.1e-36 122.8 0.0 9.7e-36 122.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EPE36940.1 - 1.7e-33 115.0 0.0 3.3e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EPE36940.1 - 5.2e-17 62.1 0.0 1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EPE36940.1 - 2.8e-12 46.1 0.6 8.3e-12 44.5 0.1 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EPE36940.1 - 5.9e-11 41.6 0.0 1.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EPE36940.1 - 6.2e-08 32.2 0.0 1.4e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EPE36940.1 - 6.2e-06 25.6 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EPE36940.1 - 0.0049 16.5 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like RimK PF08443.6 EPE36940.1 - 0.0052 16.2 0.0 0.014 14.9 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EPE36940.1 - 0.012 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 EPE36940.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.1 EPE36940.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Toxin_59 PF15537.1 EPE36940.1 - 0.16 12.0 0.0 0.51 10.4 0.0 1.8 1 0 0 1 1 1 0 Putative toxin 59 SH3_1 PF00018.23 EPE36941.1 - 3e-09 36.1 0.1 4.9e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPE36941.1 - 2.2e-07 30.3 0.0 4.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPE36941.1 - 4e-06 26.2 0.0 7.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MerC PF03203.9 EPE36941.1 - 1.6 9.1 7.7 2.3 8.6 5.3 1.2 1 0 0 1 1 1 0 MerC mercury resistance protein PRA1 PF03208.14 EPE36941.1 - 2.8 7.2 7.2 6.1 6.1 3.9 1.9 2 0 0 2 2 2 0 PRA1 family protein DUF1129 PF06570.6 EPE36941.1 - 3.2 7.0 7.7 2.4 7.4 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) TRAM_LAG1_CLN8 PF03798.11 EPE36942.1 - 3.2e-45 154.1 17.6 3.2e-45 154.1 12.2 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EPE36942.1 - 2.3e-20 71.8 0.0 6e-20 70.5 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein Bax1-I PF01027.15 EPE36943.1 - 3e-51 173.9 27.1 3.6e-51 173.7 18.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.2 EPE36943.1 - 0.00018 20.7 9.9 0.0003 20.0 6.9 1.3 1 1 0 1 1 1 1 Bax inhibitor 1 like DUF2910 PF11139.3 EPE36943.1 - 0.01 14.9 0.8 0.01 14.9 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2910) DUF2636 PF11120.3 EPE36943.1 - 0.093 12.2 0.5 0.48 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) zf-C2H2_4 PF13894.1 EPE36944.1 - 7.4e-05 22.8 8.8 0.0094 16.2 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPE36944.1 - 9.4e-05 22.5 7.9 0.046 14.0 1.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 EPE36944.1 - 0.002 18.1 1.4 0.017 15.2 0.0 2.2 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EPE36944.1 - 0.013 15.6 0.6 0.013 15.6 0.4 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 EPE36944.1 - 0.045 13.3 8.5 0.061 12.9 1.4 2.3 1 1 1 2 2 2 0 GAGA factor Sina PF03145.11 EPE36944.1 - 0.18 11.4 1.5 0.26 10.9 1.0 1.1 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_2 PF12756.2 EPE36944.1 - 0.47 10.5 4.9 8 6.6 2.0 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ecm33 PF12454.3 EPE36946.1 - 0.0042 16.9 0.9 0.013 15.3 0.6 1.8 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Carboxyl_trans PF01039.17 EPE36947.1 - 8.8e-141 469.6 0.1 1.1e-140 469.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.19 EPE36948.1 - 9.6e-42 142.6 0.7 1.9e-41 141.6 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EPE36948.1 - 7.4e-31 107.0 0.0 1.6e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EPE36948.1 - 4.1e-21 74.2 1.7 7.7e-21 73.3 0.2 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EPE36948.1 - 7.7e-15 55.3 0.1 1.8e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EPE36948.1 - 0.0028 17.0 0.7 0.021 14.2 0.2 2.4 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal PHD PF00628.24 EPE36949.1 - 3.2e-10 39.5 2.3 7.5e-10 38.3 1.6 1.6 1 0 0 1 1 1 1 PHD-finger UIM PF02809.15 EPE36949.1 - 0.01 15.3 0.2 0.032 13.7 0.1 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif PHD_2 PF13831.1 EPE36949.1 - 0.14 11.4 3.6 0.25 10.6 2.5 1.4 1 0 0 1 1 1 0 PHD-finger GA PF01468.12 EPE36951.1 - 0.038 14.1 0.2 0.098 12.8 0.1 1.6 1 0 0 1 1 1 0 GA module Cu_amine_oxid PF01179.15 EPE36955.1 - 4e-169 562.7 0.0 4.9e-169 562.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EPE36955.1 - 4e-06 26.8 0.5 9.9e-06 25.5 0.1 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EPE36955.1 - 0.00035 20.5 0.0 0.00078 19.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain IBN_N PF03810.14 EPE36956.1 - 1.7e-13 50.2 1.5 1.1e-11 44.4 0.0 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.5 EPE36956.1 - 5.2e-05 21.9 0.2 0.0002 20.0 0.0 2.1 2 0 0 2 2 2 1 Cse1 HEAT_2 PF13646.1 EPE36956.1 - 6.7e-05 23.0 0.2 0.61 10.4 0.0 3.0 2 0 0 2 2 2 2 HEAT repeats Xpo1 PF08389.7 EPE36956.1 - 0.0014 18.5 4.7 0.063 13.1 0.1 3.8 4 0 0 4 4 4 2 Exportin 1-like protein DUF2435 PF10363.4 EPE36956.1 - 0.0046 16.8 0.4 0.025 14.4 0.3 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) Mcp5_PH PF12814.2 EPE36957.1 - 2.5e-41 140.4 0.0 5.6e-41 139.3 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF2142 PF09913.4 EPE36957.1 - 0.46 9.0 0.2 0.81 8.2 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) zf-C3HC4_3 PF13920.1 EPE36958.1 - 1.9e-09 37.0 3.6 2.9e-09 36.4 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPE36958.1 - 8.8e-09 35.2 8.8 1.6e-08 34.4 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EPE36958.1 - 3.6e-08 32.8 2.4 6.7e-08 32.0 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.20 EPE36958.1 - 3e-07 29.9 7.5 5.6e-07 29.1 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPE36958.1 - 3.7e-07 29.7 7.1 6.2e-07 29.0 4.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPE36958.1 - 1e-06 28.4 5.5 1.7e-06 27.7 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EPE36958.1 - 0.0002 20.9 2.6 0.00049 19.7 1.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EPE36958.1 - 0.00098 18.9 6.8 0.0023 17.7 4.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Cript PF10235.4 EPE36958.1 - 2.2 8.7 9.8 0.63 10.4 3.8 2.3 2 2 0 2 2 2 0 Microtubule-associated protein CRIPT zf-rbx1 PF12678.2 EPE36958.1 - 3.1 7.9 6.2 12 6.1 4.3 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger Abhydro_lipase PF04083.11 EPE36959.1 - 5.7e-21 73.6 0.1 1.5e-20 72.2 0.1 1.8 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EPE36959.1 - 4.7e-17 62.3 0.1 4.9e-16 58.9 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPE36959.1 - 4.1e-07 30.1 0.0 8.5e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE36959.1 - 2.3e-06 27.4 0.0 1.2e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPE36959.1 - 0.0038 16.6 0.1 2.7 7.3 0.0 2.5 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EPE36959.1 - 0.03 13.7 0.1 5.1 6.4 0.0 2.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.4 EPE36960.1 - 2e-27 95.0 3.2 3e-27 94.4 2.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.7 EPE36960.1 - 0.012 15.1 0.7 0.038 13.5 0.3 1.9 2 0 0 2 2 2 0 PAN-like domain DUF1993 PF09351.5 EPE36961.1 - 2.2e-47 161.0 0.0 2.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) 2OG-FeII_Oxy_3 PF13640.1 EPE36962.1 - 2.7e-10 40.6 0.0 5.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EPE36962.1 - 0.0006 19.4 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SWIRM PF04433.12 EPE36966.1 - 1.6e-14 53.7 0.0 2.8e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain Thioredox_DsbH PF03190.10 EPE36967.1 - 2.3e-70 235.5 0.0 3.9e-70 234.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EPE36967.1 - 8.5e-10 38.5 0.0 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_76 PF03663.9 EPE36967.1 - 5.3e-06 26.0 0.0 9.3e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Thioredoxin_2 PF13098.1 EPE36967.1 - 0.024 14.8 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain A_deaminase PF00962.17 EPE36971.1 - 2.3e-40 138.5 0.0 2.9e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase RRM_1 PF00076.17 EPE36972.1 - 4.7e-18 64.5 0.0 1e-12 47.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPE36972.1 - 4.8e-10 39.2 0.0 2.7e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPE36972.1 - 0.18 11.6 0.0 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 EPE36973.1 - 1.4e-42 145.6 37.0 8.1e-40 136.5 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE36973.1 - 6.3e-09 34.9 7.1 8.9e-09 34.4 4.9 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 EPE36973.1 - 0.0057 16.4 0.5 2.4 8.0 0.0 3.0 2 0 0 2 2 2 2 MFS_1 like family DUF1129 PF06570.6 EPE36973.1 - 0.052 12.8 1.4 3.8 6.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) p450 PF00067.17 EPE36974.1 - 6.1e-61 206.3 0.0 8.1e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EPE36975.1 - 2.4e-05 23.9 2.1 5.7e-05 22.7 1.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPE36975.1 - 3e-05 23.5 1.2 6.7e-05 22.4 0.8 1.6 1 0 0 1 1 1 1 F-box domain Pex16 PF08610.5 EPE36976.1 - 7e-104 347.4 0.9 7.9e-104 347.2 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Nucleos_tra2_N PF01773.15 EPE36976.1 - 0.07 13.4 0.7 2.6 8.4 0.2 2.3 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus Alpha-L-AF_C PF06964.7 EPE36977.1 - 2.2e-32 112.2 0.5 3.1e-32 111.7 0.3 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 EPE36977.1 - 0.0072 16.3 0.1 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain NTS PF15447.1 EPE36978.1 - 0.0089 16.3 0.2 0.03 14.6 0.2 1.9 1 0 0 1 1 1 1 N-terminal segments of PfEMP1 Fungal_trans_2 PF11951.3 EPE36979.1 - 3.4e-09 35.7 2.0 3.8e-09 35.6 0.5 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE36979.1 - 6e-09 35.6 8.6 1.1e-08 34.7 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DJ-1_PfpI PF01965.19 EPE36980.1 - 1.7e-22 79.4 0.0 3.7e-22 78.3 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EPE36980.1 - 0.00019 20.8 0.0 0.00058 19.3 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Glyco_hydro_10 PF00331.15 EPE36981.1 - 5.5e-96 321.3 0.3 7e-96 321.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 APH PF01636.18 EPE36982.1 - 1.8e-08 34.4 0.0 3.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPE36982.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcoRII-C PF09019.6 EPE36983.1 - 0.031 14.1 0.1 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 EcoRII C terminal adh_short PF00106.20 EPE36985.1 - 2.5e-29 102.3 0.2 3.6e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPE36985.1 - 6.5e-15 55.5 0.0 7.9e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPE36985.1 - 7.8e-11 41.9 0.1 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPE36985.1 - 7.1e-07 29.4 0.0 2.1e-06 27.8 0.0 1.8 1 1 1 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPE36985.1 - 2.4e-05 23.4 0.0 3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EPE36985.1 - 0.00036 20.6 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EPE36985.1 - 0.0036 16.7 0.0 0.011 15.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EPE36985.1 - 0.0081 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1451 PF07295.6 EPE36985.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Ras PF00071.17 EPE36987.1 - 6.5e-45 152.4 0.0 7.9e-45 152.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPE36987.1 - 6.3e-17 62.1 0.0 1e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPE36987.1 - 9.4e-09 34.7 0.0 1.1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPE36987.1 - 3e-06 26.8 0.0 9.7e-05 21.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EPE36987.1 - 0.0021 18.0 0.9 0.19 11.6 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EPE36987.1 - 0.0092 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EPE36987.1 - 0.015 15.4 0.1 0.14 12.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 EPE36987.1 - 0.017 14.9 0.1 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EPE36987.1 - 0.05 12.6 0.0 0.18 10.7 0.0 1.8 2 0 0 2 2 2 0 Septin SRPRB PF09439.5 EPE36987.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 EPE36987.1 - 0.12 11.7 0.1 0.39 10.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain MFS_2 PF13347.1 EPE36990.1 - 4.3e-07 28.6 29.1 7.6e-05 21.2 20.1 2.4 1 1 0 1 1 1 1 MFS/sugar transport protein Fungal_trans_2 PF11951.3 EPE36991.1 - 2.3e-10 39.6 0.5 3.5e-10 39.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE36991.1 - 2.1e-07 30.7 8.4 3.8e-07 29.9 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trp_repressor PF01371.14 EPE36991.1 - 0.016 15.1 0.0 0.091 12.6 0.0 2.3 2 0 0 2 2 2 0 Trp repressor protein DUF605 PF04652.11 EPE36991.1 - 1.8 7.8 13.4 2.7 7.3 9.3 1.2 1 0 0 1 1 1 0 Vta1 like Nop14 PF04147.7 EPE36992.1 - 0.23 9.3 22.2 0.22 9.4 15.4 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EPE36992.1 - 4.7 5.5 25.2 6.1 5.2 17.5 1.1 1 0 0 1 1 1 0 Daxx Family Glyco_hydro_2_C PF02836.12 EPE36995.1 - 1e-103 346.3 0.0 1.8e-103 345.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EPE36995.1 - 4.1e-58 196.6 0.0 7.2e-58 195.7 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EPE36995.1 - 6.9e-55 185.1 0.8 1.5e-54 184.0 0.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EPE36995.1 - 2.8e-14 53.4 0.1 1.1e-13 51.5 0.1 2.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF1574 PF07611.6 EPE36997.1 - 1.2 7.9 3.0 0.89 8.3 0.2 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1574) Glyco_hydro_17 PF00332.13 EPE36998.1 - 1.2e-29 103.3 0.5 1.3e-28 99.9 0.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF4434 PF14488.1 EPE36998.1 - 0.019 14.6 0.1 0.11 12.2 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4434) PQ-loop PF04193.9 EPE36999.1 - 7.3e-39 131.1 8.6 6.9e-20 70.3 0.0 2.8 3 0 0 3 3 3 2 PQ loop repeat DUF1774 PF08611.5 EPE36999.1 - 0.046 13.8 0.8 0.14 12.3 0.5 1.9 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1774) NAD_binding_10 PF13460.1 EPE37000.1 - 4.9e-12 46.2 0.0 5.8e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE37000.1 - 6.5e-06 25.5 0.0 8.8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EPE37000.1 - 0.078 12.9 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 EPE37000.1 - 0.084 12.2 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 EPE37001.1 - 7.8e-60 202.7 0.0 3.4e-58 197.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 HET PF06985.6 EPE37003.1 - 7.2e-29 100.7 0.0 1.4e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EPE37004.1 - 3.7e-18 65.3 42.2 8.5e-17 60.8 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPE37004.1 - 0.00043 18.9 32.0 0.02 13.4 22.2 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_M43 PF05572.8 EPE37005.1 - 2.5e-15 56.4 0.7 4.4e-15 55.6 0.5 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EPE37005.1 - 1.9e-07 31.1 1.3 3e-07 30.5 0.9 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EPE37005.1 - 9.6e-06 25.7 0.5 1.5e-05 25.1 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EPE37005.1 - 3.7e-05 23.3 0.3 5.3e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EPE37005.1 - 7.6e-05 23.2 1.7 0.00015 22.3 1.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EPE37005.1 - 0.00014 20.8 0.6 0.00019 20.4 0.4 1.2 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.19 EPE37005.1 - 0.003 17.2 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Matrixin Metallopep PF12044.3 EPE37005.1 - 0.024 13.0 0.6 0.034 12.5 0.4 1.2 1 0 0 1 1 1 0 Putative peptidase family Arabinose_trans PF04602.7 EPE37005.1 - 0.083 11.0 3.0 0.73 7.9 0.2 2.1 1 1 1 2 2 2 0 Mycobacterial cell wall arabinan synthesis protein DUF4148 PF13663.1 EPE37005.1 - 0.44 10.4 4.8 0.62 9.9 0.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4148) Ring_hydroxyl_A PF00848.14 EPE37006.1 - 3.5e-27 95.4 0.1 2e-26 92.9 0.1 1.9 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EPE37007.1 - 3.5e-17 61.7 0.0 6.1e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.14 EPE37007.1 - 0.00089 18.9 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) WG_beta_rep PF14903.1 EPE37007.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 WG containing repeat AA_permease_2 PF13520.1 EPE37008.1 - 2.8e-46 157.9 41.7 3.8e-46 157.4 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE37008.1 - 2.8e-20 72.1 33.4 4.2e-20 71.5 23.2 1.1 1 0 0 1 1 1 1 Amino acid permease Esterase_phd PF10503.4 EPE37010.1 - 1.7e-22 79.7 0.6 2.3e-22 79.3 0.4 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EPE37010.1 - 3e-09 36.4 0.6 5.3e-09 35.6 0.4 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPE37010.1 - 8.9e-05 22.2 0.5 0.00012 21.7 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPE37010.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_76 PF03663.9 EPE37012.1 - 2.3e-32 112.7 0.1 3.1e-32 112.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EPE37012.1 - 1.3e-06 27.6 0.1 0.00018 20.6 0.0 2.3 1 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 Prenyltrans_2 PF13249.1 EPE37012.1 - 2.2e-05 24.8 0.4 0.028 14.7 0.0 2.9 1 1 2 3 3 3 2 Prenyltransferase-like C5-epim_C PF06662.8 EPE37012.1 - 0.008 15.4 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus p450 PF00067.17 EPE37014.1 - 1.4e-56 191.9 0.0 1.9e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 But2 PF09792.4 EPE37016.1 - 1.2e-06 28.3 0.5 1.6e-06 27.9 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain AAA_33 PF13671.1 EPE37017.1 - 4.5e-10 39.5 0.0 5.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPE37017.1 - 4.3e-09 36.7 0.0 7.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPE37017.1 - 1.5e-07 30.6 0.0 2.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EPE37017.1 - 4.5e-07 30.6 0.0 7.1e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EPE37017.1 - 0.0087 15.4 0.0 0.017 14.5 0.0 1.6 1 1 1 2 2 2 1 Dephospho-CoA kinase AAA_16 PF13191.1 EPE37017.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.9 EPE37017.1 - 0.035 13.0 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain APS_kinase PF01583.15 EPE37017.1 - 0.047 13.3 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.5 EPE37017.1 - 0.057 12.6 0.0 0.076 12.2 0.0 1.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_13 PF13166.1 EPE37017.1 - 0.061 11.7 0.0 0.084 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EPE37017.1 - 0.068 13.3 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPE37017.1 - 0.1 12.9 0.1 0.21 11.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 EPE37017.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EPE37017.1 - 0.12 11.9 0.3 0.62 9.6 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Fungal_trans PF04082.13 EPE37018.1 - 2.3e-08 33.2 0.1 3.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 EPE37019.1 - 3.7e-81 272.3 0.0 6.5e-81 271.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPE37019.1 - 7.8e-63 212.0 0.0 1.6e-62 210.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPE37019.1 - 4.2e-20 71.4 0.0 8.5e-20 70.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EPE37019.1 - 1.2e-08 34.6 0.3 3.1e-08 33.3 0.2 1.7 1 0 0 1 1 1 1 PA14 domain DUF3564 PF12087.3 EPE37019.1 - 0.036 13.6 0.1 0.086 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) Sugar_tr PF00083.19 EPE37020.1 - 3e-74 250.2 25.4 3.6e-74 249.9 17.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPE37020.1 - 2.4e-12 46.2 27.8 1.1e-11 44.0 18.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 EPE37021.1 - 2.3e-12 46.5 9.4 3.1e-12 46.1 6.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DHHC PF01529.15 EPE37021.1 - 0.32 10.3 2.7 0.41 10.0 1.9 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Dickkopf_N PF04706.7 EPE37021.1 - 2.1 8.5 10.8 3.9 7.7 7.5 1.4 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Fungal_trans PF04082.13 EPE37022.1 - 8.6e-20 70.6 0.1 1.5e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EPE37024.1 - 2e-48 164.9 63.9 4.3e-47 160.5 42.9 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPE37024.1 - 6.8e-17 60.8 15.7 1e-16 60.3 10.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPE37024.1 - 4.3e-15 55.2 16.9 4.3e-15 55.2 11.7 3.2 1 1 2 3 3 3 2 Sugar (and other) transporter p450 PF00067.17 EPE37028.1 - 3.7e-10 38.9 0.0 4.1e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EPE37030.1 - 2.3e-19 69.7 0.0 3.7e-06 26.2 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.22 EPE37030.1 - 1.4e-05 25.3 0.0 0.095 13.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE37030.1 - 8.7e-05 21.5 0.0 0.0079 15.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPE37030.1 - 0.00011 22.1 0.2 0.00024 21.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EPE37030.1 - 0.00019 20.0 0.3 0.001 17.6 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EPE37030.1 - 0.00064 19.6 0.0 0.0014 18.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPE37030.1 - 0.00068 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EPE37030.1 - 0.0021 17.2 0.2 0.36 9.8 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EPE37030.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EPE37030.1 - 0.018 14.0 0.1 0.046 12.6 0.0 1.8 2 1 0 2 2 2 0 Lycopene cyclase protein M20_dimer PF07687.9 EPE37030.1 - 0.042 13.5 0.1 0.091 12.5 0.1 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain AlaDh_PNT_C PF01262.16 EPE37030.1 - 0.047 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 EPE37030.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EPE37030.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EPE37030.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 EPE37031.1 - 1.6e-19 70.2 0.0 2.5e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE37031.1 - 9.8e-07 29.1 0.0 5.5e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE37031.1 - 1e-06 28.4 0.0 1.5e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPE37031.1 - 4.8e-06 26.9 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE37031.1 - 1.4e-05 25.6 0.0 0.00014 22.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPE37031.1 - 0.0067 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EPE37031.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EPE37031.1 - 0.023 13.7 0.0 0.049 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EPE37031.1 - 0.03 13.4 0.0 0.42 9.6 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EPE37031.1 - 0.11 12.5 0.0 3.3 7.7 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 EPE37031.1 - 0.14 12.1 0.2 0.44 10.5 0.0 1.9 2 1 1 3 3 3 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EPE37031.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF2296 PF10058.4 EPE37033.1 - 2.7e-19 68.6 0.1 5.2e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) BLUF PF04940.7 EPE37033.1 - 0.0072 16.0 0.1 0.62 9.8 0.0 2.5 2 0 0 2 2 2 2 Sensors of blue-light using FAD GRIP PF01465.15 EPE37034.1 - 5.2e-06 25.8 0.1 1.3e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 EPE37034.1 - 0.0013 18.3 14.2 0.0013 18.3 9.9 7.6 3 3 4 7 7 7 4 IncA protein Phage_GP20 PF06810.6 EPE37034.1 - 0.0058 16.0 10.1 0.0058 16.0 7.0 10.7 4 2 5 11 11 11 2 Phage minor structural protein GP20 DUF4201 PF13870.1 EPE37034.1 - 0.0075 15.7 2.5 0.0075 15.7 1.7 8.9 4 2 5 9 9 9 2 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 EPE37034.1 - 0.017 14.3 40.7 0.024 13.8 2.2 6.5 3 2 2 6 6 6 0 Reovirus sigma C capsid protein WD40_alt PF14077.1 EPE37034.1 - 0.15 11.6 12.7 2 8.0 0.1 5.1 4 1 0 4 4 4 0 Alternative WD40 repeat motif TPR_MLP1_2 PF07926.7 EPE37034.1 - 2.3 7.9 120.9 2.4 7.9 4.0 10.1 4 2 6 10 10 10 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.20 EPE37035.1 - 2e-40 138.5 0.2 1.5e-24 86.5 0.1 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPE37035.1 - 5.2e-15 55.2 0.2 8.8e-11 41.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Brr6_like_C_C PF10104.4 EPE37036.1 - 1.8e-39 134.3 0.1 2.2e-39 134.0 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain TIP_N PF12457.3 EPE37036.1 - 0.023 14.7 0.9 0.046 13.8 0.7 1.5 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal Med26 PF08711.6 EPE37037.1 - 7.7e-12 44.5 0.0 1.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain ORC6 PF05460.8 EPE37037.1 - 0.17 10.9 6.8 0.3 10.1 4.7 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HLH PF00010.21 EPE37038.1 - 1.9e-17 62.7 0.6 3.5e-17 61.8 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 EPE37038.1 - 0.0072 16.2 0.5 0.021 14.7 0.2 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EPE37038.1 - 0.017 14.9 0.3 0.072 12.9 0.0 2.0 2 0 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.13 EPE37038.1 - 0.11 12.5 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Fungal_trans PF04082.13 EPE37039.1 - 4e-26 91.4 0.7 6e-26 90.8 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE37039.1 - 1.2e-07 31.5 9.2 2.3e-07 30.6 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase_3 PF07732.10 EPE37040.1 - 1.1e-39 134.8 4.1 8.5e-37 125.4 0.1 3.5 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPE37040.1 - 2.2e-31 108.1 4.9 1e-30 106.0 0.5 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EPE37040.1 - 2.9e-16 59.7 0.0 8.5e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase Phosphoesterase PF04185.9 EPE37041.1 - 1e-57 196.0 0.1 2e-57 195.1 0.0 1.4 1 1 0 1 1 1 1 Phosphoesterase family RAMP PF04901.8 EPE37042.1 - 0.014 15.1 0.7 0.053 13.2 0.0 2.1 3 0 0 3 3 3 0 Receptor activity modifying family PaaX_C PF08223.6 EPE37044.1 - 0.045 13.4 1.2 0.12 12.0 0.1 1.9 1 1 1 2 2 2 0 PaaX-like protein C-terminal domain Rogdi_lz PF10259.4 EPE37046.1 - 0.0019 17.3 0.1 0.032 13.3 0.1 2.0 2 0 0 2 2 2 2 Rogdi leucine zipper containing protein PNGaseA PF12222.3 EPE37048.1 - 7.5e-150 499.5 10.4 1.5e-149 498.5 7.2 1.4 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A EamA PF00892.15 EPE37049.1 - 3.7e-16 59.3 25.4 2.8e-11 43.5 4.6 3.2 2 2 2 4 4 4 2 EamA-like transporter family EmrE PF13536.1 EPE37049.1 - 2e-06 27.9 5.7 2e-06 27.9 4.0 3.1 2 1 0 3 3 3 1 Multidrug resistance efflux transporter TFIID-18kDa PF02269.11 EPE37050.1 - 7.6e-20 70.5 0.1 1.1e-19 69.9 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 EPE37050.1 - 0.02 15.0 0.1 0.044 13.9 0.0 1.7 2 0 0 2 2 2 0 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPE37050.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPE37050.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated ADH_zinc_N_2 PF13602.1 EPE37051.1 - 0.1 13.4 1.0 0.21 12.5 0.7 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ribosom_S12_S23 PF00164.20 EPE37052.1 - 6.8e-41 138.5 0.3 7.9e-41 138.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 SUR7 PF06687.7 EPE37053.1 - 2.2e-44 151.6 20.8 2.6e-44 151.3 14.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Oleosin PF01277.12 EPE37053.1 - 0.004 16.6 0.2 0.0071 15.9 0.1 1.4 1 0 0 1 1 1 1 Oleosin DEAD PF00270.24 EPE37055.1 - 7.8e-19 67.7 0.0 2.9e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPE37055.1 - 2.3e-18 65.8 0.0 3.9e-16 58.6 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPE37055.1 - 0.081 11.6 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain PP2C PF00481.16 EPE37056.1 - 8.7e-43 146.5 0.0 1.5e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EPE37056.1 - 0.0009 18.9 0.0 0.097 12.3 0.0 2.5 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EPE37056.1 - 0.015 14.6 0.1 0.05 12.9 0.1 1.8 1 1 0 1 1 1 0 Protein phosphatase 2C Tcf25 PF04910.9 EPE37057.1 - 6.8e-80 268.7 1.0 6.8e-80 268.7 0.7 1.5 2 0 0 2 2 2 1 Transcriptional repressor TCF25 TATR PF03430.8 EPE37057.1 - 3.6 6.1 7.1 4.8 5.6 4.9 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Nop53 PF07767.6 EPE37057.1 - 4.2 6.2 22.0 11 4.8 15.2 1.7 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) HMA PF00403.21 EPE37058.1 - 6.3e-10 39.0 2.6 0.00029 20.9 0.4 2.3 2 0 0 2 2 2 2 Heavy-metal-associated domain Thiolase_C PF02803.13 EPE37059.1 - 4.9e-12 45.3 1.5 1.4e-11 43.9 0.0 2.4 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EPE37059.1 - 1.1e-06 28.1 0.0 6.1e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EPE37059.1 - 3.7e-05 22.8 0.1 0.0001 21.3 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EPE37059.1 - 9.6e-05 21.9 0.0 0.00021 20.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EPE37059.1 - 0.027 14.3 0.0 4.2 7.2 0.0 2.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Gly-zipper_OmpA PF13436.1 EPE37060.1 - 0.12 12.0 25.1 1.3 8.6 0.2 5.5 5 0 0 5 5 5 0 Glycine-zipper containing OmpA-like membrane domain Glyco_hydro_61 PF03443.9 EPE37061.1 - 3.5e-67 226.4 0.1 4.1e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Tcp11 PF05794.8 EPE37062.1 - 1.9e-80 270.7 4.9 6.4e-76 255.8 0.9 2.1 2 0 0 2 2 2 2 T-complex protein 11 Myotub-related PF06602.9 EPE37063.1 - 0.15 10.7 0.0 0.32 9.7 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain TGT PF01702.13 EPE37065.1 - 8.2e-87 290.4 0.0 1e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase adh_short PF00106.20 EPE37067.1 - 1.2e-15 57.8 0.3 1.7e-15 57.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE37067.1 - 1.3e-07 31.4 0.1 2e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPE37067.1 - 0.00048 20.1 0.1 0.00083 19.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPE37067.1 - 0.02 14.1 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 EPE37067.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EPE37067.1 - 0.087 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HET PF06985.6 EPE37069.1 - 2.8e-32 111.7 0.1 5.1e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MOZ_SAS PF01853.13 EPE37070.1 - 1.5e-84 281.9 0.8 2.2e-84 281.4 0.6 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EPE37070.1 - 3.8e-18 64.9 0.0 2.3e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.1 EPE37070.1 - 0.085 13.0 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE37070.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pox_Ag35 PF03286.9 EPE37070.1 - 0.27 10.7 5.4 0.48 9.9 3.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNase_T PF00929.19 EPE37071.1 - 2.7e-25 89.5 0.0 4.9e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EPE37071.1 - 0.00018 21.0 0.0 0.00073 19.0 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease CMAS PF02353.15 EPE37072.1 - 2.7e-71 239.8 0.0 5.1e-71 238.9 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EPE37072.1 - 1.9e-11 44.2 0.0 4.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPE37072.1 - 6.1e-10 39.0 0.0 9.8e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPE37072.1 - 2.8e-09 37.5 0.0 5.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPE37072.1 - 2e-06 27.4 0.0 3.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPE37072.1 - 3.7e-05 24.1 0.0 7.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPE37072.1 - 0.00014 21.8 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EPE37072.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.4 EPE37072.1 - 0.028 13.8 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF2877 PF11392.3 EPE37072.1 - 0.029 14.5 0.1 0.16 12.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) DUF938 PF06080.7 EPE37072.1 - 0.057 12.9 0.0 0.46 9.9 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 EPE37072.1 - 0.14 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNase_H2_suC PF08615.6 EPE37074.1 - 5.9e-33 113.6 0.0 7e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PD40 PF07676.7 EPE37074.1 - 0.089 12.4 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat DUF4385 PF14328.1 EPE37075.1 - 1.9e-54 183.5 3.0 1.9e-54 183.5 2.1 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4385) AbiH PF14253.1 EPE37075.1 - 0.0065 16.1 0.9 0.0082 15.7 0.6 1.1 1 0 0 1 1 1 1 Bacteriophage abortive infection AbiH MCM PF00493.18 EPE37076.1 - 6.1e-135 449.2 0.2 9.4e-135 448.6 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPE37076.1 - 8.9e-20 71.3 0.0 2.8e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPE37076.1 - 2.7e-08 33.2 0.0 8.4e-07 28.3 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EPE37076.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EPE37076.1 - 0.0015 18.1 0.0 0.0034 16.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPE37076.1 - 0.0035 17.0 0.0 0.018 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RPAP1_N PF08621.5 EPE37076.1 - 0.11 12.1 0.3 0.28 10.7 0.2 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal Hist_deacetyl PF00850.14 EPE37077.1 - 3.5e-59 200.6 0.0 5.5e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DUF1699 PF08004.6 EPE37078.1 - 0.16 11.5 0.0 0.64 9.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1699) Lon_C PF05362.8 EPE37080.1 - 6e-69 231.4 0.2 1.2e-68 230.4 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EPE37080.1 - 1.9e-27 96.3 0.0 4e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EPE37080.1 - 2.2e-23 82.8 0.0 6.1e-23 81.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPE37080.1 - 3.9e-08 33.1 0.0 1.2e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EPE37080.1 - 5.8e-08 32.2 0.0 1.5e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_3 PF07726.6 EPE37080.1 - 9.1e-06 25.3 0.0 2.8e-05 23.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPE37080.1 - 3.2e-05 24.7 0.0 0.00011 23.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPE37080.1 - 4.4e-05 23.5 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EPE37080.1 - 6.5e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EPE37080.1 - 7.3e-05 22.7 0.0 0.00028 20.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EPE37080.1 - 0.00022 21.1 0.0 0.0046 16.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EPE37080.1 - 0.00022 20.3 0.1 0.00088 18.3 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EPE37080.1 - 0.00065 19.4 0.4 0.0047 16.6 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain TIP49 PF06068.8 EPE37080.1 - 0.00066 18.5 0.2 0.0032 16.2 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus AAA_22 PF13401.1 EPE37080.1 - 0.0019 18.3 0.0 0.015 15.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPE37080.1 - 0.0055 16.1 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPE37080.1 - 0.0068 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EPE37080.1 - 0.0095 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPE37080.1 - 0.014 15.7 0.0 0.044 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPE37080.1 - 0.022 14.9 0.3 0.079 13.1 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.1 EPE37080.1 - 0.028 14.0 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EPE37080.1 - 0.028 14.1 0.0 0.079 12.6 0.0 1.8 1 0 0 1 1 1 0 NTPase UPF0079 PF02367.12 EPE37080.1 - 0.032 13.8 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 EPE37080.1 - 0.036 13.2 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EPE37080.1 - 0.038 13.6 0.0 0.12 11.9 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.10 EPE37080.1 - 0.045 12.4 0.1 0.075 11.7 0.1 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Mg_chelatase PF01078.16 EPE37080.1 - 0.066 12.3 0.1 0.18 10.9 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 EPE37080.1 - 0.081 11.6 0.1 3.9 6.0 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain AAA_23 PF13476.1 EPE37080.1 - 0.4 10.9 0.0 0.4 10.9 0.0 3.5 2 1 1 3 3 2 0 AAA domain PLDc_2 PF13091.1 EPE37081.1 - 1.3e-17 63.6 0.0 3.9e-11 42.7 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EPE37081.1 - 0.0023 17.7 0.3 0.0091 15.7 0.1 2.0 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EPE37081.1 - 0.052 12.5 0.1 0.15 10.9 0.0 1.8 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Ku PF02735.11 EPE37082.1 - 1.4e-25 89.8 0.0 2.9e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EPE37082.1 - 9.3e-14 51.3 0.1 2e-13 50.2 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EPE37082.1 - 1.4e-13 50.8 0.0 3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like DUF4149 PF13664.1 EPE37083.1 - 2e-24 85.5 1.5 2e-24 85.5 1.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Neugrin PF06413.6 EPE37084.1 - 0.0082 15.9 0.8 0.0082 15.9 0.6 2.3 2 1 1 3 3 3 1 Neugrin IncA PF04156.9 EPE37084.1 - 0.068 12.7 21.7 0.02 14.5 8.9 2.9 3 0 0 3 3 3 0 IncA protein DUF2205 PF10224.4 EPE37084.1 - 0.11 12.1 11.8 0.4 10.2 2.6 4.3 4 1 0 4 4 4 0 Predicted coiled-coil protein (DUF2205) Nsp1_C PF05064.8 EPE37084.1 - 0.13 11.9 8.0 0.97 9.0 0.1 2.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region Caudo_TAP PF02413.12 EPE37084.1 - 3.8 7.7 8.1 6.2 7.0 3.7 2.3 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein Ax_dynein_light PF10211.4 EPE37084.1 - 4.1 7.1 19.3 0.095 12.5 6.6 2.6 2 1 0 2 2 2 0 Axonemal dynein light chain MA3 PF02847.12 EPE37085.1 - 1.6e-27 95.4 0.0 7.7e-27 93.2 0.0 2.2 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 EPE37085.1 - 1.6e-27 96.2 1.1 1.6e-27 96.2 0.7 1.8 2 0 0 2 2 2 1 MIF4G domain DPM2 PF07297.7 EPE37086.1 - 4.9e-35 119.6 1.4 6e-35 119.3 1.0 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EPE37086.1 - 5.4e-05 22.8 1.4 6.2e-05 22.6 1.0 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EPE37086.1 - 0.0002 21.1 0.8 0.0002 21.1 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) Herpes_UL43 PF05072.8 EPE37086.1 - 0.026 13.3 0.6 0.069 11.8 0.2 1.7 2 0 0 2 2 2 0 Herpesvirus UL43 protein Cytochrom_C_asm PF01578.15 EPE37086.1 - 0.038 13.5 0.1 0.044 13.3 0.1 1.0 1 0 0 1 1 1 0 Cytochrome C assembly protein DUF1049 PF06305.6 EPE37086.1 - 0.088 12.2 0.2 0.088 12.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF4083 PF13314.1 EPE37086.1 - 0.16 11.8 0.2 0.16 11.8 0.1 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4083) PspC PF04024.7 EPE37086.1 - 0.5 9.8 4.2 3.2 7.3 0.2 2.1 2 0 0 2 2 2 0 PspC domain TPPK_C PF12555.3 EPE37086.1 - 2.1 8.1 7.4 0.14 11.8 1.2 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal AAA_13 PF13166.1 EPE37088.1 - 0.0047 15.4 0.7 0.006 15.1 0.5 1.1 1 0 0 1 1 1 1 AAA domain DUF4358 PF14270.1 EPE37088.1 - 0.0055 16.5 0.2 0.019 14.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4358) RRF PF01765.14 EPE37088.1 - 0.01 15.2 1.0 0.016 14.6 0.6 1.4 1 1 0 1 1 1 0 Ribosome recycling factor Prefoldin_2 PF01920.15 EPE37088.1 - 0.059 13.1 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Prefoldin subunit AAA_32 PF13654.1 EPE37088.1 - 0.071 11.7 0.3 0.087 11.4 0.2 1.1 1 0 0 1 1 1 0 AAA domain LUC7 PF03194.10 EPE37088.1 - 0.11 12.0 1.0 0.14 11.6 0.7 1.1 1 0 0 1 1 1 0 LUC7 N_terminus ART PF01129.13 EPE37088.1 - 0.17 10.9 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Seryl_tRNA_N PF02403.17 EPE37088.1 - 0.34 10.9 5.0 0.2 11.6 1.2 2.2 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SET PF00856.23 EPE37089.1 - 4.6e-06 27.0 0.4 0.094 13.0 0.1 3.0 2 2 0 2 2 2 2 SET domain TPR_16 PF13432.1 EPE37089.1 - 0.64 10.7 4.4 2.4 8.9 0.7 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat zf-MYND PF01753.13 EPE37089.1 - 0.73 9.7 11.0 0.029 14.2 2.3 2.7 2 0 0 2 2 2 0 MYND finger Hydrolase_6 PF13344.1 EPE37090.1 - 1.5e-29 101.8 0.0 2.5e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPE37090.1 - 1.7e-12 46.8 0.0 2.1e-11 43.3 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EPE37090.1 - 3.4e-11 43.9 0.0 3e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPE37090.1 - 5.2e-06 26.7 0.0 0.00021 21.5 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EPE37090.1 - 0.058 12.7 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Glucosamine_iso PF01182.15 EPE37091.1 - 7.4e-57 192.2 0.0 9.1e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CFEM PF05730.6 EPE37092.1 - 0.00057 19.6 1.6 0.00057 19.6 1.1 2.5 2 0 0 2 2 2 1 CFEM domain Snf7 PF03357.16 EPE37093.1 - 1.8e-12 47.0 9.9 2.1e-12 46.7 6.9 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EPE37093.1 - 0.017 14.4 2.5 0.02 14.2 1.7 1.1 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway CPSase_L_D3 PF02787.14 EPE37093.1 - 0.048 13.4 0.6 0.07 12.8 0.4 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF244 PF03112.9 EPE37093.1 - 0.057 12.9 3.1 0.066 12.7 1.6 1.4 1 1 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Bap31 PF05529.7 EPE37093.1 - 0.94 8.8 4.1 1.4 8.3 2.8 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Ank_5 PF13857.1 EPE37094.1 - 2.1e-05 24.6 0.0 5.8e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EPE37094.1 - 0.00037 20.1 0.2 0.00076 19.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EPE37094.1 - 0.0028 17.9 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPE37094.1 - 0.022 15.2 0.0 0.047 14.2 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Acyl-CoA_dh_1 PF00441.19 EPE37095.1 - 6.8e-41 139.8 5.0 1.2e-40 139.0 3.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EPE37095.1 - 5.3e-29 101.0 0.9 3.3e-28 98.5 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EPE37095.1 - 1.5e-16 59.5 0.1 4.6e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EPE37095.1 - 6.8e-16 58.7 1.9 1.1e-15 58.0 1.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Myelin-PO_C PF10570.4 EPE37095.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Myelin-PO cytoplasmic C-term p65 binding region MFS_1 PF07690.11 EPE37096.1 - 1.1e-24 86.7 45.2 1.6e-16 60.0 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily eIF-1a PF01176.14 EPE37097.1 - 1.8e-18 65.6 0.0 3.7e-18 64.6 0.0 1.5 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.8 EPE37098.1 - 5.7e-139 463.4 19.5 6.6e-139 463.2 13.5 1.0 1 0 0 1 1 1 1 ALG3 protein DUF1978 PF09321.5 EPE37099.1 - 0.026 13.9 1.5 0.16 11.3 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) NYN_YacP PF05991.6 EPE37099.1 - 0.044 13.5 0.4 0.053 13.2 0.3 1.1 1 0 0 1 1 1 0 YacP-like NYN domain CorA PF01544.13 EPE37099.1 - 0.1 11.5 0.2 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4398 PF14346.1 EPE37099.1 - 0.19 11.8 3.5 0.24 11.4 2.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) DUF883 PF05957.8 EPE37099.1 - 0.61 10.5 4.7 12 6.3 0.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) HAD PF12710.2 EPE37100.1 - 2.8e-12 47.2 0.0 4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPE37100.1 - 0.00017 20.8 0.1 0.034 13.3 0.0 2.3 1 1 0 2 2 2 2 Putative Phosphatase HAD_2 PF13419.1 EPE37100.1 - 0.0006 20.0 0.0 0.0015 18.7 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EPE37100.1 - 0.00062 19.1 0.0 0.0016 17.7 0.0 1.7 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 EPE37100.1 - 0.049 14.0 0.0 6.3 7.1 0.0 2.6 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase She9_MDM33 PF05546.6 EPE37101.1 - 5.9e-88 293.8 4.0 9.6e-88 293.1 2.8 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EPE37101.1 - 0.016 14.7 0.9 0.031 13.8 0.6 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Glyco_hydro_35 PF01301.14 EPE37102.1 - 4.3e-86 289.1 0.0 7.2e-86 288.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EPE37102.1 - 2.8e-62 209.3 7.4 4.5e-62 208.6 5.1 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EPE37102.1 - 4.5e-52 175.0 12.6 5.2e-30 103.9 3.6 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EPE37102.1 - 2.7e-20 71.5 0.1 9.8e-20 69.7 0.1 2.0 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Ribosom_S12_S23 PF00164.20 EPE37103.1 - 4.3e-39 132.6 1.2 5.5e-39 132.3 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 FAD_binding_3 PF01494.14 EPE37104.1 - 6.6e-20 71.4 0.9 1.9e-18 66.6 0.7 2.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EPE37104.1 - 7.8e-10 38.9 0.2 3.4e-09 36.8 0.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPE37104.1 - 5.1e-09 35.4 0.1 7.3e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPE37104.1 - 6.5e-09 35.1 0.0 1.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EPE37104.1 - 1.9e-08 33.2 0.9 0.00015 20.3 0.0 2.5 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 EPE37104.1 - 7.7e-08 31.5 0.2 0.00027 19.9 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EPE37104.1 - 1.4e-06 28.2 0.0 3.2e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE37104.1 - 2.4e-06 26.7 0.1 0.002 17.0 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EPE37104.1 - 5.8e-06 25.6 0.1 1.1e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPE37104.1 - 0.00012 21.2 0.0 0.00022 20.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EPE37104.1 - 0.00026 21.3 0.4 0.04 14.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPE37104.1 - 0.0017 18.1 0.2 3.5 7.3 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPE37104.1 - 0.0021 18.1 0.1 0.0087 16.1 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EPE37104.1 - 0.0027 16.8 0.1 0.32 10.0 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 EPE37104.1 - 0.0058 16.2 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EPE37104.1 - 0.0061 15.2 0.1 1.6 7.3 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase p450 PF00067.17 EPE37105.1 - 5.1e-51 173.6 0.0 6.6e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sybindin PF04099.7 EPE37105.1 - 0.12 12.0 0.0 8.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Sybindin-like family DUF1772 PF08592.6 EPE37106.1 - 6.2e-16 58.3 0.4 1e-15 57.7 0.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) TrbL PF04610.9 EPE37106.1 - 0.014 15.0 0.8 0.018 14.7 0.6 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Cas_Csx9 PF09658.5 EPE37106.1 - 0.032 13.0 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) NmrA PF05368.8 EPE37108.1 - 5e-28 97.9 0.1 6.6e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPE37108.1 - 5e-14 52.7 0.1 7.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPE37108.1 - 1.9e-05 23.7 0.2 0.038 12.9 0.1 2.2 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.16 EPE37108.1 - 5e-05 22.8 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EPE37108.1 - 0.00011 22.1 0.1 0.00016 21.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EPE37108.1 - 0.00024 19.8 0.0 0.00031 19.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EPE37108.1 - 0.00045 19.9 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.15 EPE37108.1 - 0.0012 18.8 0.1 0.0025 17.7 0.1 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EPE37108.1 - 0.0044 16.0 0.1 0.0063 15.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EPE37108.1 - 0.027 14.7 0.1 0.061 13.6 0.1 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Aminotran_5 PF00266.14 EPE37109.1 - 2.5e-19 69.2 0.0 1.2e-18 67.0 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V GST_C_3 PF14497.1 EPE37110.1 - 2.2e-08 34.4 0.0 3.5e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPE37110.1 - 0.0019 18.3 0.1 0.014 15.5 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPE37110.1 - 0.04 13.8 0.0 0.06 13.2 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain p450 PF00067.17 EPE37112.1 - 8.9e-26 90.4 0.1 1.5e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_2 PF02230.11 EPE37116.1 - 6.2e-20 71.5 0.0 9.6e-15 54.6 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EPE37116.1 - 1.6e-05 24.9 0.0 3.3e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE37116.1 - 0.024 14.3 0.0 0.052 13.2 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.13 EPE37117.1 - 1.1e-08 34.8 12.2 2e-08 33.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPE37117.1 - 0.005 15.4 0.0 0.012 14.2 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ldl_recept_a PF00057.13 EPE37117.1 - 0.0073 16.1 5.4 0.017 14.9 3.7 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A XRCC4 PF06632.7 EPE37118.1 - 3.2e-07 29.5 4.9 4.4e-07 29.0 3.4 1.3 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 EthD PF07110.6 EPE37120.1 - 1.2e-12 48.6 0.0 1.5e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 EthD domain CHAT PF12770.2 EPE37121.1 - 3.7e-41 141.1 0.2 5.8e-41 140.5 0.1 1.3 1 0 0 1 1 1 1 CHAT domain AMP-binding_C_2 PF14535.1 EPE37121.1 - 0.069 13.1 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain SKG6 PF08693.5 EPE37123.1 - 0.11 11.7 1.3 0.57 9.5 0.9 2.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Neisseria_TspB PF05616.8 EPE37123.1 - 0.33 9.2 17.0 0.42 8.9 11.8 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Mid2 PF04478.7 EPE37123.1 - 0.64 9.4 21.0 0.018 14.4 7.7 2.8 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor Peptidase_M56 PF05569.6 EPE37123.1 - 0.87 8.5 3.3 0.5 9.2 0.1 1.8 1 1 1 2 2 2 0 BlaR1 peptidase M56 PAT1 PF09770.4 EPE37123.1 - 6.3 4.8 7.2 7.6 4.6 5.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cellulase PF00150.13 EPE37124.1 - 6.2e-43 147.0 2.8 8.4e-43 146.5 1.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 EPE37124.1 - 2.8e-18 65.5 1.6 1.9e-17 62.8 0.3 2.7 3 0 0 3 3 3 1 Carbohydrate binding domain X2 DUF4390 PF14334.1 EPE37124.1 - 0.012 14.8 0.1 0.025 13.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) Peptidase_C39 PF03412.10 EPE37124.1 - 0.022 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family tRNA-synt_1f PF01921.13 EPE37126.1 - 0.003 16.2 0.0 0.029 13.0 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (K) DUF2654 PF10849.3 EPE37130.1 - 0.072 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) Adeno_E3_14_5 PF04834.7 EPE37130.1 - 0.12 12.8 3.1 0.16 12.4 1.0 2.0 2 0 0 2 2 2 0 Early E3 14.5 kDa protein zf-DHHC PF01529.15 EPE37130.1 - 0.81 9.0 2.7 1.8 7.9 1.9 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF1118 PF06549.7 EPE37131.1 - 7.6 6.7 6.6 4.5 7.4 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) Amidoligase_2 PF12224.3 EPE37132.1 - 1e-17 64.5 0.1 3.2e-16 59.7 0.1 2.1 1 1 0 1 1 1 1 Putative amidoligase enzyme RdRP PF05183.7 EPE37134.1 - 2.5e-104 350.0 0.5 4.3e-104 349.3 0.3 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase Corona_NS2 PF04753.7 EPE37134.1 - 0.085 12.8 0.1 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 Abhydrolase_6 PF12697.2 EPE37135.1 - 4.4e-16 59.4 0.0 6.5e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPE37135.1 - 1.7e-07 31.0 0.0 6.5e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPE37135.1 - 0.0024 17.3 0.2 0.0042 16.5 0.1 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 EPE37135.1 - 0.019 14.8 0.0 0.11 12.3 0.0 2.3 4 0 0 4 4 4 0 Putative lysophospholipase LIP PF03583.9 EPE37135.1 - 0.1 11.7 0.1 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase AA_permease_2 PF13520.1 EPE37136.1 - 4.2e-43 147.4 53.9 5.3e-43 147.1 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPE37136.1 - 1.7e-21 76.1 35.8 1.7e-21 76.1 24.8 1.7 2 0 0 2 2 2 1 Amino acid permease Acetyltransf_7 PF13508.1 EPE37137.1 - 3.3e-09 36.7 0.5 7.6e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPE37137.1 - 7.9e-09 35.4 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPE37137.1 - 3.5e-06 27.1 0.3 2.3e-05 24.4 0.2 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPE37137.1 - 0.00018 21.3 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPE37137.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 EPE37137.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein TSGP1 PF07771.6 EPE37139.1 - 0.52 10.1 3.0 0.75 9.6 2.1 1.3 1 0 0 1 1 1 0 Tick salivary peptide group 1 DAO PF01266.19 EPE37140.1 - 2.1e-55 188.0 0.1 2.5e-55 187.8 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPE37140.1 - 9.6e-05 22.5 0.0 0.025 14.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPE37140.1 - 0.0064 16.3 0.2 0.1 12.4 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPE37140.1 - 0.012 15.5 0.1 0.027 14.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPE37140.1 - 0.032 13.1 0.2 0.082 11.8 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EPE37140.1 - 0.036 13.8 0.3 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EPE37140.1 - 0.055 12.3 0.1 0.16 10.7 0.1 1.7 1 1 0 1 1 1 0 FAD binding domain SLBB PF10531.4 EPE37140.1 - 0.079 12.8 0.2 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 SLBB domain Ank PF00023.25 EPE37142.1 - 1.3e-07 31.0 0.1 0.00013 21.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EPE37142.1 - 2.1e-05 24.5 0.0 0.00013 22.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPE37142.1 - 5.2e-05 23.4 0.0 0.0019 18.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPE37142.1 - 0.034 14.3 0.0 0.44 10.9 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeat Spore_YhcN_YlaJ PF09580.5 EPE37142.1 - 0.2 11.7 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Matrilin_ccoil PF10393.4 EPE37142.1 - 0.39 10.1 2.6 16 4.9 0.0 3.9 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF948 PF06103.6 EPE37142.1 - 2.3 8.1 6.7 1.7 8.5 0.4 3.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Ank PF00023.25 EPE37143.1 - 3.1e-07 29.8 0.0 9.7e-05 21.9 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EPE37143.1 - 0.00029 21.1 0.0 0.027 14.7 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPE37143.1 - 0.0014 18.8 0.0 0.0051 17.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPE37143.1 - 0.0025 17.8 0.3 0.57 10.5 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Syntaxin_2 PF14523.1 EPE37143.1 - 0.011 15.7 3.8 0.011 15.7 2.6 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF1128 PF06569.6 EPE37143.1 - 0.029 14.0 0.2 0.46 10.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) Flagellin_N PF00669.15 EPE37143.1 - 0.086 12.6 1.7 0.16 11.7 1.2 1.5 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region DBINO PF13892.1 EPE37144.1 - 0.0039 17.2 16.2 0.005 16.8 11.2 1.0 1 0 0 1 1 1 1 DNA-binding domain She9_MDM33 PF05546.6 EPE37144.1 - 0.14 11.6 10.6 0.17 11.4 7.4 1.0 1 0 0 1 1 1 0 She9 / Mdm33 family UPF0172 PF03665.8 EPE37144.1 - 0.21 11.0 2.2 0.2 11.0 1.2 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF2201_N PF13203.1 EPE37144.1 - 0.29 10.2 8.6 0.34 10.0 5.9 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain CAF-1_p150 PF11600.3 EPE37144.1 - 0.32 10.3 21.9 0.43 9.9 15.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CHD5 PF04420.9 EPE37144.1 - 2.1 7.9 7.2 2.3 7.8 5.0 1.1 1 0 0 1 1 1 0 CHD5-like protein Ku_C PF03730.9 EPE37144.1 - 2.4 8.7 8.1 3.4 8.2 5.5 1.3 1 1 0 1 1 1 0 Ku70/Ku80 C-terminal arm HET PF06985.6 EPE37144.1 - 4.7 7.3 7.4 8.9 6.4 5.1 1.6 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Herpes_DNAp_acc PF04929.7 EPE37144.1 - 6.4 5.6 12.1 7.3 5.4 8.4 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Corona_nucleoca PF00937.13 EPE37144.1 - 7.3 5.4 13.9 8.7 5.1 9.6 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SprA-related PF12118.3 EPE37144.1 - 7.7 5.7 13.1 9.7 5.4 9.1 1.0 1 0 0 1 1 1 0 SprA-related family DUF221 PF02714.10 EPE37145.1 - 6e-101 337.5 12.7 6e-101 337.5 8.8 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPE37145.1 - 4.2e-40 136.8 2.4 4.2e-40 136.8 1.7 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EPE37145.1 - 8.2e-27 92.9 0.0 1.6e-25 88.8 0.0 2.3 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EPE37145.1 - 8.4e-09 35.8 0.4 5.9e-08 33.1 0.3 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) EutQ PF06249.7 EPE37147.1 - 1.6e-09 37.4 0.0 2.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 EPE37147.1 - 4e-08 32.5 0.1 6.6e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 EPE37147.1 - 0.0011 18.4 0.1 0.0015 18.0 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EPE37147.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Cupin Fungal_trans_2 PF11951.3 EPE37148.1 - 8.2e-61 205.6 0.5 1.1e-60 205.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPE37148.1 - 4.4e-07 29.6 12.3 7.2e-07 29.0 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_72 PF03198.9 EPE37150.1 - 4.3e-111 370.8 0.0 6e-111 370.4 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EPE37150.1 - 0.00045 19.2 0.0 0.0012 17.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain BTB PF00651.26 EPE37151.1 - 0.00015 21.7 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF4448 PF14610.1 EPE37152.1 - 0.0057 16.1 0.1 0.0066 15.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1180 PF06679.7 EPE37152.1 - 0.054 13.3 0.9 0.065 13.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Plasmodium_Vir PF05795.6 EPE37152.1 - 0.11 11.7 0.1 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3357 PF11837.3 EPE37153.1 - 0.083 12.7 0.6 0.23 11.3 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) NfeD PF01957.13 EPE37153.1 - 0.3 11.1 2.3 0.26 11.4 0.4 1.6 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Herpes_US9 PF06072.6 EPE37153.1 - 0.46 10.3 2.7 0.46 10.3 0.8 1.9 1 1 1 2 2 2 0 Alphaherpesvirus tegument protein US9 UPF0016 PF01169.14 EPE37153.1 - 1.3 9.2 7.8 0.19 11.8 0.3 2.6 1 1 2 3 3 3 0 Uncharacterized protein family UPF0016 DUF1664 PF07889.7 EPE37154.1 - 0.0027 17.4 0.9 2.5 7.8 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) MCC-bdg_PDZ PF10506.4 EPE37154.1 - 0.0074 16.0 0.5 0.024 14.4 0.3 1.9 1 0 0 1 1 1 1 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF869 PF05911.6 EPE37154.1 - 0.019 13.2 0.7 0.034 12.4 0.5 1.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) FliJ PF02050.11 EPE37154.1 - 0.1 12.6 0.6 19 5.3 0.0 3.2 3 0 0 3 3 3 0 Flagellar FliJ protein Sec8_exocyst PF04048.9 EPE37154.1 - 0.1 12.2 2.9 3 7.4 0.0 2.8 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Med9 PF07544.8 EPE37154.1 - 0.26 11.0 2.1 0.63 9.8 0.0 2.7 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Prominin PF05478.6 EPE37154.1 - 0.56 7.6 3.3 0.45 7.9 0.7 1.8 2 0 0 2 2 2 0 Prominin Filament PF00038.16 EPE37154.1 - 0.59 9.5 3.3 2 7.8 0.1 2.5 2 1 1 3 3 3 0 Intermediate filament protein NPV_P10 PF05531.7 EPE37154.1 - 0.6 10.4 4.4 9.8 6.5 0.1 3.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Daxx PF03344.10 EPE37155.1 - 7 5.0 16.2 10 4.4 11.3 1.1 1 0 0 1 1 1 0 Daxx Family Rax2 PF12768.2 EPE37156.1 - 0.002 17.3 0.0 0.0024 17.1 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Glycophorin_A PF01102.13 EPE37156.1 - 0.025 14.3 0.5 0.045 13.5 0.4 1.4 1 0 0 1 1 1 0 Glycophorin A DZR PF12773.2 EPE37157.1 - 0.037 13.8 0.2 0.055 13.2 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon PolC_DP2 PF03833.8 EPE37157.1 - 0.15 9.6 0.1 0.12 9.9 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc_ribbon_2 PF13240.1 EPE37157.1 - 0.35 10.4 2.1 1.1 8.8 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Pec_lyase_C PF00544.14 EPE37158.1 - 3.7e-34 117.9 11.9 6.5e-34 117.1 8.3 1.4 1 1 0 1 1 1 1 Pectate lyase Ribosomal_L5_C PF00673.16 EPE37159.1 - 2.1e-13 49.8 0.0 2.9e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Glyco_hydro_43 PF04616.9 EPE37160.1 - 2.7e-50 171.0 6.7 3.8e-50 170.5 3.6 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 EPE37160.1 - 2.8e-24 85.6 6.6 6.7e-24 84.4 4.6 1.7 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 EPE37160.1 - 0.012 15.0 2.1 0.019 14.3 1.5 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain DUF924 PF06041.6 EPE37162.1 - 3.6e-54 183.3 0.0 6.7e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) VEGF_C PF14554.1 EPE37162.1 - 0.35 10.7 15.6 0.67 9.7 10.8 1.4 1 0 0 1 1 1 0 VEGF heparin-binding domain Polysacc_deac_1 PF01522.16 EPE37164.1 - 0.002 17.7 0.0 0.0064 16.1 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase NmrA PF05368.8 EPE37165.1 - 2e-14 53.4 0.0 5e-14 52.1 0.0 1.6 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EPE37165.1 - 1.2e-08 35.1 0.0 3e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EPE37165.1 - 0.071 12.7 0.1 0.55 9.8 0.0 2.1 2 1 1 3 3 3 0 KR domain adh_short_C2 PF13561.1 EPE37166.1 - 2e-25 89.9 0.2 2.4e-25 89.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPE37166.1 - 7.9e-21 74.6 3.2 1.3e-20 73.9 2.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE37166.1 - 2.6e-05 23.9 2.1 9.6e-05 22.1 1.5 1.8 1 1 0 1 1 1 1 KR domain Kp4 PF09044.5 EPE37166.1 - 0.081 12.7 0.2 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Kp4 p450 PF00067.17 EPE37167.1 - 2.2e-48 164.9 0.0 2.8e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ComX PF05952.7 EPE37167.1 - 0.13 11.7 0.0 0.63 9.5 0.0 2.1 1 1 1 2 2 2 0 Bacillus competence pheromone ComX p450 PF00067.17 EPE37168.1 - 1e-57 195.7 0.1 1.3e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.14 EPE37169.1 - 4.1e-44 150.3 0.0 5.2e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPE37169.1 - 5.8e-31 107.7 0.0 7.3e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPE37169.1 - 6.5e-17 61.2 0.0 4e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EPE37169.1 - 1.9e-10 40.0 0.0 2.8e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPE37169.1 - 2.2e-09 37.5 0.0 3.1e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPE37169.1 - 7.5e-09 35.7 0.0 1.5e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPE37169.1 - 1.2e-06 28.2 0.0 4.2e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPE37169.1 - 8.4e-06 24.8 0.0 5.1e-05 22.3 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EPE37169.1 - 0.0027 17.0 0.0 0.034 13.3 0.0 2.1 1 1 1 2 2 2 1 NmrA-like family DapB_N PF01113.15 EPE37169.1 - 0.05 13.5 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EPE37169.1 - 0.057 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.17 EPE37170.1 - 1.4e-24 86.5 0.0 4.2e-23 81.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 EPE37172.1 - 1.8e-32 112.4 42.6 4.2e-32 111.2 29.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily