# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- FAD_binding_8 PF08022.12 KPA35114.1 - 1.3e-05 25.2 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 FAD-binding domain FAM117 PF15388.6 KPA35115.1 - 0.024 14.1 0.6 0.042 13.3 0.6 1.3 1 0 0 1 1 1 0 Protein Family FAM117 DUF1479 PF07350.12 KPA35116.1 - 1.4e-14 53.8 0.3 1.6e-14 53.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Polysacc_deac_1 PF01522.21 KPA35117.1 - 1.7e-12 47.3 0.0 2.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase OrsD PF12013.8 KPA35118.1 - 1.5e-13 51.2 0.1 3.1e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Nore1-SARAH PF16517.5 KPA35118.1 - 0.39 10.6 3.4 0.71 9.8 3.4 1.4 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain tify PF06200.14 KPA35119.1 - 0.65 9.4 2.9 12 5.3 0.1 3.8 4 0 0 4 4 4 0 tify domain DHODB_Fe-S_bind PF10418.9 KPA35119.1 - 1 9.2 7.5 12 5.8 0.7 3.6 2 1 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B DUF1939 PF09154.10 KPA35120.1 - 0.099 12.8 0.1 5.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) FAD-oxidase_C PF02913.19 KPA35122.1 - 7.7e-19 68.3 0.1 8.9e-19 68.1 0.1 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Nsp1 PF11501.8 KPA35122.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.3 1 1 0 1 1 1 0 Non structural protein Nsp1 Glyco_hydro_28 PF00295.17 KPA35124.1 - 4.4e-40 137.7 5.4 5.3e-40 137.4 5.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short PF00106.25 KPA35125.1 - 3.8e-23 82.0 0.0 4.8e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA35125.1 - 5.2e-17 62.2 0.0 6.9e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA35125.1 - 8.6e-06 25.8 0.1 1.1e-05 25.5 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA35125.1 - 6.6e-05 22.5 0.0 0.00015 21.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPA35125.1 - 0.02 14.8 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding HET PF06985.11 KPA35126.1 - 4.5e-36 124.4 0.3 7.1e-36 123.7 0.3 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sec20 PF03908.13 KPA35126.1 - 0.0053 16.7 0.0 0.0081 16.1 0.0 1.2 1 0 0 1 1 1 1 Sec20 RCC_reductase PF06405.11 KPA35126.1 - 0.057 12.6 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) MAT1 PF06391.13 KPA35128.1 - 0.0076 16.1 2.6 0.0099 15.7 2.6 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 CDC45 PF02724.14 KPA35128.1 - 0.23 9.7 7.7 0.3 9.3 7.7 1.0 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 KPA35129.1 - 2.8e-14 52.8 9.7 3.5e-14 52.5 9.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPA35129.1 - 2.3e-07 30.5 1.9 2.9e-07 30.1 1.9 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF3784 PF12650.7 KPA35129.1 - 0.072 13.3 2.6 0.4 10.9 1.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) tRNA-synt_2c PF01411.19 KPA35130.1 - 1.1e-08 34.1 0.0 1.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KPA35130.1 - 1.9e-06 27.8 0.3 3.5e-06 27.0 0.3 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TFIIA PF03153.13 KPA35131.1 - 0.15 12.1 16.4 0.18 11.8 16.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-BED PF02892.15 KPA35132.1 - 0.0072 16.3 0.3 0.02 14.9 0.3 1.8 1 0 0 1 1 1 1 BED zinc finger Mre11_DNA_bind PF04152.14 KPA35134.1 - 1.3e-36 126.5 0.1 1.3e-36 126.5 0.1 2.6 3 1 0 3 3 3 1 Mre11 DNA-binding presumed domain PI3K_1B_p101 PF10486.9 KPA35134.1 - 0.13 10.1 1.3 0.19 9.5 1.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4326 PF14216.6 KPA35134.1 - 0.14 12.9 0.1 0.65 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) DUF4811 PF16069.5 KPA35134.1 - 0.14 12.0 2.0 5.4 6.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) SRP-alpha_N PF04086.13 KPA35134.1 - 3.1 7.6 23.6 5.1 6.9 23.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4551 PF15087.6 KPA35134.1 - 8.9 5.0 12.3 13 4.5 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) YojJ PF10372.9 KPA35135.1 - 2.7e-05 24.2 0.1 0.0003 20.8 0.1 2.8 2 1 2 4 4 4 2 Bacterial membrane-spanning protein N-terminus Golgin_A5 PF09787.9 KPA35135.1 - 0.0014 18.1 3.5 0.0014 18.1 3.5 2.4 2 0 0 2 2 2 1 Golgin subfamily A member 5 TelA PF05816.11 KPA35135.1 - 0.006 15.7 0.5 0.006 15.7 0.5 1.6 2 0 0 2 2 2 1 Toxic anion resistance protein (TelA) IFT57 PF10498.9 KPA35135.1 - 0.0096 14.9 2.5 0.0096 14.9 2.5 2.1 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 Hemagglutinin PF00509.18 KPA35135.1 - 0.019 13.4 0.1 0.028 12.8 0.1 1.3 1 0 0 1 1 1 0 Haemagglutinin DUF1664 PF07889.12 KPA35135.1 - 0.095 12.7 6.1 0.92 9.6 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KPA35135.1 - 0.14 12.2 0.2 1.2 9.1 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.13 KPA35135.1 - 0.14 12.9 9.2 0.34 11.7 1.1 3.2 2 1 1 3 3 3 0 Occludin homology domain Exonuc_VII_L PF02601.15 KPA35135.1 - 0.32 10.5 8.7 0.23 11.0 0.1 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF16 PF01519.16 KPA35135.1 - 3.2 8.3 9.7 0.52 10.8 1.3 3.0 2 1 1 3 3 3 0 Protein of unknown function DUF16 Filament PF00038.21 KPA35135.1 - 3.5 7.1 13.6 1.2 8.6 1.8 2.9 2 2 0 2 2 2 0 Intermediate filament protein DUF4618 PF15397.6 KPA35135.1 - 5.1 6.4 10.1 2.2 7.7 2.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) XhlA PF10779.9 KPA35135.1 - 7.3 6.9 10.3 8 6.8 0.2 3.3 3 0 0 3 3 3 0 Haemolysin XhlA Glyco_hydro_1 PF00232.18 KPA35136.1 - 1e-70 238.5 0.0 1.3e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 EHN PF06441.12 KPA35137.1 - 1.2e-28 99.7 0.5 1.4e-28 99.4 0.5 1.0 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Glyco_hydro_32N PF00251.20 KPA35138.1 - 1.2e-39 136.7 0.8 1.5e-39 136.4 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KPA35138.1 - 8.5e-20 71.3 0.2 1.3e-19 70.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Dicty_CAD PF05720.12 KPA35138.1 - 0.15 12.0 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Cell-cell adhesion domain CobS_N PF12556.8 KPA35140.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal WD40 PF00400.32 KPA35143.1 - 5e-12 46.1 0.2 1.1e-11 45.1 0.2 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA35143.1 - 0.012 15.9 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA35143.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_S15 PF02129.18 KPA35145.1 - 4.3e-10 39.6 0.0 6.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) RRM_1 PF00076.22 KPA35146.1 - 1.1e-10 41.2 0.0 2.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flavoprotein PF02441.19 KPA35148.1 - 2.9e-14 53.1 0.0 3.5e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Dimer_Tnp_hAT PF05699.14 KPA35149.1 - 1.8e-16 59.7 0.1 3.1e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region adh_short_C2 PF13561.6 KPA35150.1 - 7.4e-29 101.0 0.7 9.6e-29 100.6 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA35150.1 - 3.4e-20 72.3 0.8 6.3e-20 71.5 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPA35150.1 - 6e-07 29.5 0.2 1.1e-06 28.6 0.2 1.6 1 1 0 1 1 1 1 KR domain LamB PF02264.15 KPA35150.1 - 0.062 13.2 0.1 0.088 12.7 0.1 1.1 1 0 0 1 1 1 0 LamB porin BppU_N PF10651.9 KPA35150.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 BppU N-terminal domain Eno-Rase_NADH_b PF12242.8 KPA35150.1 - 0.31 10.8 3.3 0.55 10.0 2.5 1.8 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.25 KPA35151.1 - 1.2e-31 109.7 0.4 4.8e-23 81.7 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA35151.1 - 2.2e-20 73.2 0.1 4.9e-15 55.7 0.2 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA35151.1 - 1.5e-14 54.3 0.0 2.4e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA35151.1 - 4.2e-07 29.4 0.1 5.7e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPA35151.1 - 0.0036 16.8 0.5 0.28 10.6 0.2 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA35151.1 - 0.0065 15.5 0.1 0.0092 15.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KPA35151.1 - 0.029 14.4 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KPA35151.1 - 0.036 13.4 1.1 0.053 12.9 0.1 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 KPA35153.1 - 1.8e-51 175.4 0.0 2e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF835 PF05763.12 KPA35153.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF835) DLH PF01738.18 KPA35154.1 - 9.1e-18 64.6 0.0 1.1e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KPA35154.1 - 0.017 14.6 0.5 0.055 12.9 0.0 2.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family p450 PF00067.22 KPA35155.1 - 3.7e-17 62.2 0.0 4.4e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MmgE_PrpD PF03972.14 KPA35157.1 - 1.5e-104 350.0 3.5 1.8e-104 349.7 3.5 1.0 1 0 0 1 1 1 1 MmgE/PrpD family BPL_N PF09825.9 KPA35158.1 - 7.4e-09 35.1 0.4 1.8e-05 24.0 0.3 2.2 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal PDZ_1 PF12812.7 KPA35159.1 - 3.3e-14 52.6 0.0 3.9e-13 49.2 0.0 2.5 2 0 0 2 2 2 1 PDZ-like domain Trypsin_2 PF13365.6 KPA35159.1 - 0.00056 20.8 0.1 0.0016 19.3 0.0 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 KPA35159.1 - 0.0048 17.2 0.0 0.28 11.5 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KPA35159.1 - 0.099 12.5 0.0 0.9 9.4 0.0 2.2 2 0 0 2 2 2 0 PDZ domain Iso_dh PF00180.20 KPA35162.1 - 3.2e-60 204.1 0.0 3.9e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase p450 PF00067.22 KPA35165.1 - 6.5e-14 51.5 0.0 7.8e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_T4_Gp30_7 PF06919.11 KPA35166.1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Phage Gp30.7 protein Helo_like_N PF17111.5 KPA35167.1 - 2.6e-59 200.1 0.6 3.3e-59 199.8 0.6 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KPA35167.1 - 0.0016 18.6 0.2 0.0039 17.4 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases PhosphMutase PF10143.9 KPA35167.1 - 0.024 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase DUF2383 PF09537.10 KPA35167.1 - 0.063 13.6 0.1 0.49 10.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Spc24 PF08286.11 KPA35167.1 - 0.45 10.8 2.6 39 4.6 0.3 3.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 KPA35167.1 - 1.5 8.9 4.6 7.3 6.7 3.1 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein AKNA PF12443.8 KPA35167.1 - 6.5 7.5 6.7 8.3 7.1 0.1 3.1 2 2 2 4 4 4 0 AT-hook-containing transcription factor SlyX PF04102.12 KPA35167.1 - 8.6 7.1 8.2 75 4.0 0.7 4.0 4 1 0 5 5 5 0 SlyX Helicase_C PF00271.31 KPA35168.1 - 0.028 14.8 0.0 0.057 13.8 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DDHD PF02862.17 KPA35169.1 - 0.4 10.8 5.6 0.45 10.6 5.6 1.0 1 0 0 1 1 1 0 DDHD domain Roughex PF06020.11 KPA35169.1 - 0.48 9.5 4.6 0.52 9.4 4.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 KPA35169.1 - 5.1 5.8 5.8 5.5 5.7 5.8 1.0 1 0 0 1 1 1 0 Presenilin Helicase_C PF00271.31 KPA35170.1 - 2.4e-11 44.0 0.0 1e-10 42.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPA35170.1 - 1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Phage_Orf51 PF06194.11 KPA35174.1 - 0.8 9.8 3.3 1.3 9.0 3.3 1.5 1 1 0 1 1 1 0 Phage Conserved Open Reading Frame 51 ANAPC5 PF12862.7 KPA35177.1 - 2.5e-37 126.8 3.6 9.4e-35 118.6 3.3 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 KPA35177.1 - 0.36 10.8 2.2 0.43 10.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat OrsD PF12013.8 KPA35178.1 - 1.8e-09 38.1 0.0 3.7e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf_C2H2_ZHX PF18387.1 KPA35178.1 - 0.01 15.5 2.7 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KPA35178.1 - 0.12 12.8 0.1 0.34 11.3 0.0 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Rubredoxin_2 PF18073.1 KPA35178.1 - 1.7 8.5 3.9 0.63 9.8 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-C2H2 PF00096.26 KPA35178.1 - 4.5 7.9 5.7 3.2 8.4 1.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type RSN1_TM PF13967.6 KPA35179.1 - 1.1e-21 77.2 0.0 1.3e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3760 PF12586.8 KPA35180.1 - 0.07 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) Dimer_Tnp_hAT PF05699.14 KPA35182.1 - 4.3e-17 61.7 0.3 9.7e-17 60.5 0.3 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Peptidase_S66 PF02016.15 KPA35183.1 - 5.1e-27 94.4 0.0 6.1e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain NFACT-C PF11923.8 KPA35185.1 - 0.14 12.1 0.0 0.94 9.4 0.0 2.1 1 1 1 2 2 2 0 NFACT protein C-terminal domain adh_short PF00106.25 KPA35188.1 - 8.6e-18 64.5 0.1 1.1e-17 64.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA35188.1 - 3.2e-09 36.7 0.0 5.5e-09 35.9 0.0 1.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA35188.1 - 4.5e-08 33.2 0.1 8.3e-08 32.3 0.1 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA35188.1 - 3.8e-05 23.0 0.1 4.6e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KPA35188.1 - 0.062 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase_fungal PF17667.1 KPA35190.1 - 2.5e-91 306.5 0.0 3.1e-91 306.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Melibiase_2 PF16499.5 KPA35190.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A TRP PF06011.12 KPA35191.1 - 1.1e-69 235.2 11.2 1.5e-69 234.8 11.2 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KPA35191.1 - 5.8e-36 123.9 0.3 8.8e-36 123.3 0.3 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 KPA35191.1 - 0.0028 18.1 0.1 0.0044 17.5 0.1 1.3 1 0 0 1 1 1 1 ML domain Aldo_ket_red PF00248.21 KPA35192.1 - 4.8e-23 81.8 0.0 5.7e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family REV PF00424.18 KPA35194.1 - 1.2 9.2 8.3 0.07 13.2 1.5 2.1 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) HNH_2 PF13391.6 KPA35195.1 - 1.9e-12 47.1 0.1 5.2e-12 45.7 0.1 1.8 1 0 0 1 1 1 1 HNH endonuclease RIIa PF02197.17 KPA35195.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit HET PF06985.11 KPA35197.1 - 3.3e-28 98.9 0.0 5.3e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_32C PF08244.12 KPA35198.1 - 1.6e-22 80.2 0.1 1.9e-22 79.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KPA35198.1 - 0.00014 21.6 0.3 0.00018 21.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain DUF4987 PF16377.5 KPA35198.1 - 0.07 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function Fasciclin PF02469.22 KPA35199.1 - 2.5e-11 43.9 0.1 1.5e-08 34.9 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_61 PF03443.14 KPA35200.1 - 2.5e-05 24.3 0.0 2.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4357 PF14267.6 KPA35200.1 - 0.25 11.3 3.1 6 6.9 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4357) Peptidase_S15 PF02129.18 KPA35201.1 - 4.7e-11 42.8 0.0 6.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) COX15-CtaA PF02628.15 KPA35202.1 - 0.041 13.0 0.1 0.062 12.4 0.1 1.2 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Cyt-b5 PF00173.28 KPA35203.1 - 5.9e-20 71.2 0.0 7.2e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DHDPS PF00701.22 KPA35204.1 - 3.4e-36 124.5 0.1 4.4e-36 124.1 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HTH_Tnp_Tc3_2 PF01498.18 KPA35205.1 - 0.00013 22.2 0.3 0.00028 21.0 0.3 1.5 1 0 0 1 1 1 1 Transposase Polysacc_deac_1 PF01522.21 KPA35205.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide deacetylase PG_binding_1 PF01471.18 KPA35206.1 - 0.054 13.7 0.0 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Pkinase PF00069.25 KPA35208.1 - 1.8e-11 43.9 0.0 2.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA35208.1 - 1.5e-07 31.0 0.0 2.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPA35208.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KPA35208.1 - 0.24 10.3 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PIF1 PF05970.14 KPA35209.1 - 4.1e-06 26.2 0.0 5.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 KPA35209.1 - 0.015 15.1 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Aldo_ket_red PF00248.21 KPA35210.1 - 3e-35 121.8 0.0 3.4e-33 115.1 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family CbiX PF01903.17 KPA35210.1 - 0.022 15.1 0.0 0.087 13.2 0.0 1.9 2 0 0 2 2 2 0 CbiX DUF2167 PF09935.9 KPA35210.1 - 0.14 11.3 0.2 0.33 10.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2167) PNP_UDP_1 PF01048.20 KPA35212.1 - 2.9e-11 43.1 0.7 2.7e-10 39.9 0.7 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily DUF423 PF04241.15 KPA35214.1 - 0.036 14.3 0.0 0.091 13.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Terpene_synth_C PF03936.16 KPA35214.1 - 0.14 11.5 0.1 0.27 10.5 0.1 1.6 1 1 0 1 1 1 0 Terpene synthase family, metal binding domain SQS_PSY PF00494.19 KPA35214.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Squalene/phytoene synthase Aa_trans PF01490.18 KPA35215.1 - 4.6e-13 48.7 7.0 5.4e-13 48.4 7.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RBP_receptor PF14752.6 KPA35215.1 - 0.03 12.9 0.2 0.041 12.5 0.2 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor NADH_dh_m_C1 PF15088.6 KPA35215.1 - 0.62 9.7 2.0 9.2 6.0 0.0 2.3 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Pro_racemase PF05544.11 KPA35217.1 - 1.2e-44 152.8 0.0 3.6e-30 105.1 0.0 2.0 1 1 1 2 2 2 2 Proline racemase ParA PF10609.9 KPA35218.1 - 1.9e-93 312.4 0.1 2.4e-93 312.1 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KPA35218.1 - 3.9e-11 43.1 0.0 7.7e-09 35.7 0.1 2.3 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KPA35218.1 - 9.7e-07 28.3 0.1 2.7e-05 23.6 0.1 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KPA35218.1 - 1.6e-06 28.2 0.3 0.00024 21.1 0.2 2.3 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KPA35218.1 - 5e-05 22.6 1.2 0.00017 20.9 0.5 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 KPA35218.1 - 0.00033 20.5 0.6 0.06 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 KPA35218.1 - 0.00063 19.3 0.0 0.0014 18.2 0.0 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 KPA35218.1 - 0.00079 18.5 0.3 0.0012 17.9 0.3 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KPA35218.1 - 0.0042 16.7 0.3 0.0087 15.7 0.3 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KPA35218.1 - 0.042 13.7 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 KPA35218.1 - 0.047 14.1 0.3 0.14 12.5 0.2 1.7 2 0 0 2 2 2 0 AAA ATPase domain CLP1_P PF16575.5 KPA35218.1 - 0.062 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 KPA35218.1 - 0.077 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 KPA35218.1 - 0.086 12.5 0.2 0.95 9.1 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KPA35218.1 - 0.16 11.7 0.5 9.9 5.8 0.4 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KPA35218.1 - 0.57 10.1 3.1 0.52 10.2 1.4 1.8 2 0 0 2 2 2 0 RsgA GTPase Glyco_hydro_3 PF00933.21 KPA35219.1 - 1.6e-28 100.0 0.0 2.5e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain OrfB_Zn_ribbon PF07282.11 KPA35220.1 - 0.024 14.5 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Radial_spoke_3 PF06098.11 KPA35221.1 - 0.003 16.9 5.4 0.0076 15.6 4.5 1.9 1 1 1 2 2 2 1 Radial spoke protein 3 Amidohydro_1 PF01979.20 KPA35222.1 - 3.7e-16 59.4 0.1 6.4e-16 58.6 0.1 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPA35222.1 - 1e-10 41.8 0.3 1.9e-07 30.9 0.2 2.4 2 1 0 2 2 2 2 Amidohydrolase family NTP_transf_3 PF12804.7 KPA35222.1 - 0.013 15.9 0.1 0.022 15.1 0.1 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Amidohydro_2 PF04909.14 KPA35223.1 - 7.2e-43 147.4 0.0 8.9e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase BAH PF01426.18 KPA35224.1 - 1.8e-06 27.8 0.2 3.4e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KPA35224.1 - 0.49 10.7 4.3 0.24 11.7 0.6 2.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHD PF00628.29 KPA35224.1 - 0.56 10.1 9.7 0.049 13.5 3.9 2.1 2 0 0 2 2 2 0 PHD-finger Cutinase PF01083.22 KPA35225.1 - 5.8e-41 140.4 0.0 7.3e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPA35225.1 - 0.0011 18.6 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KPA35225.1 - 0.0025 17.7 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF3089 PF11288.8 KPA35225.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PGAP1 PF07819.13 KPA35226.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KPA35226.1 - 0.0072 16.9 0.1 0.013 16.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA35226.1 - 0.063 12.5 0.0 0.87 8.8 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Fungal_trans PF04082.18 KPA35227.1 - 1.4e-25 89.9 0.2 1.9e-25 89.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhnJ PF06007.11 KPA35227.1 - 0.061 12.3 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ bZIP_1 PF00170.21 KPA35229.1 - 0.0002 21.4 5.1 0.00039 20.4 5.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPA35229.1 - 0.00086 19.3 3.7 0.0021 18.1 3.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper SYF2 PF08231.12 KPA35230.1 - 0.032 14.6 0.3 0.039 14.3 0.3 1.1 1 0 0 1 1 1 0 SYF2 splicing factor E1-E2_ATPase PF00122.20 KPA35230.1 - 0.039 13.5 0.2 0.051 13.1 0.2 1.1 1 0 0 1 1 1 0 E1-E2 ATPase HpcH_HpaI PF03328.14 KPA35232.1 - 5.1e-18 65.0 0.1 6.7e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family FadA PF09403.10 KPA35234.1 - 0.068 13.7 0.6 0.11 12.9 0.6 1.3 1 0 0 1 1 1 0 Adhesion protein FadA DUF5453 PF17534.2 KPA35235.1 - 3.3 7.6 8.7 0.39 10.6 1.2 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5453) NACHT_N PF17100.5 KPA35236.1 - 2.3e-23 83.2 1.4 2.3e-23 83.2 1.4 2.5 4 0 0 4 4 4 1 N-terminal domain of NWD NACHT-NTPase AAA_16 PF13191.6 KPA35236.1 - 9.8e-07 29.3 6.0 4.8e-06 27.1 0.0 3.7 3 1 1 4 4 4 1 AAA ATPase domain NACHT PF05729.12 KPA35236.1 - 0.00021 21.3 0.1 0.00051 20.0 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KPA35236.1 - 0.00035 21.0 0.0 0.0016 18.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA35236.1 - 0.0023 18.2 2.7 0.011 16.0 0.0 3.3 4 0 0 4 4 4 1 AAA domain Sigma54_activ_2 PF14532.6 KPA35236.1 - 0.015 15.4 0.5 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Syntaxin_2 PF14523.6 KPA35236.1 - 0.043 14.2 4.4 0.25 11.7 4.4 2.3 1 0 0 1 1 1 0 Syntaxin-like protein KAP_NTPase PF07693.14 KPA35236.1 - 0.062 12.5 1.7 0.14 11.3 0.0 2.3 2 1 1 3 3 3 0 KAP family P-loop domain AAA_25 PF13481.6 KPA35236.1 - 0.079 12.5 0.0 2.2 7.8 0.0 3.1 2 1 0 2 2 2 0 AAA domain PolyA_pol_arg_C PF12626.7 KPA35236.1 - 0.1 12.6 0.1 0.1 12.6 0.1 2.0 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus RNA_helicase PF00910.22 KPA35236.1 - 0.12 12.8 0.0 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase dCache_2 PF08269.11 KPA35236.1 - 3.4 6.8 6.5 2.9 7.0 3.0 2.4 2 0 0 2 2 2 0 Cache domain FAD_binding_3 PF01494.19 KPA35237.1 - 3.7e-15 56.0 0.0 4.7e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPA35237.1 - 4.3e-06 26.9 0.0 9.4e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPA35237.1 - 7.3e-06 25.3 0.0 2.5e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KPA35237.1 - 1.6e-05 24.3 0.1 0.00015 21.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPA35237.1 - 4.8e-05 22.8 0.0 0.16 11.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 KPA35237.1 - 5.8e-05 22.4 0.1 0.002 17.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KPA35237.1 - 0.00021 21.0 0.1 0.00047 19.8 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA35237.1 - 0.00026 21.5 0.2 0.0025 18.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA35237.1 - 0.00073 18.9 0.1 0.0048 16.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA35237.1 - 0.00087 18.5 0.1 0.036 13.1 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KPA35237.1 - 0.0027 16.5 0.0 0.025 13.3 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KPA35237.1 - 0.0045 16.1 0.1 0.0094 15.1 0.1 1.6 1 1 1 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KPA35237.1 - 0.0061 15.5 0.0 0.0095 14.8 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.7 KPA35237.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KPA35237.1 - 0.064 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 KPA35237.1 - 0.14 12.6 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NleF_casp_inhib PF16809.5 KPA35238.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NleF caspase inhibitor DUF2277 PF10041.9 KPA35238.1 - 0.17 12.3 0.0 0.5 10.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) RAP1 PF07218.11 KPA35238.1 - 0.73 8.0 4.0 1 7.5 4.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NAD_binding_10 PF13460.6 KPA35240.1 - 0.00045 20.2 0.0 0.00063 19.7 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA35240.1 - 0.01 15.3 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KPA35240.1 - 0.026 14.9 0.0 0.059 13.8 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KPA35240.1 - 0.084 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KPA35240.1 - 0.084 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BCS1_N PF08740.11 KPA35241.1 - 2.6e-25 89.5 2.2 3.9e-25 88.9 2.2 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KPA35241.1 - 2.5e-17 63.6 0.0 1.2e-16 61.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPA35241.1 - 0.0018 18.0 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KPA35241.1 - 0.007 16.0 0.0 0.028 14.0 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 KPA35241.1 - 0.011 16.0 0.1 3.7 7.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 KPA35241.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PPV_E1_C PF00519.17 KPA35241.1 - 0.016 14.0 0.0 0.057 12.2 0.0 1.8 2 0 0 2 2 2 0 Papillomavirus helicase AAA_5 PF07728.14 KPA35241.1 - 0.031 14.3 0.0 0.33 11.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KPA35241.1 - 0.039 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 KPA35241.1 - 0.084 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPA35241.1 - 0.089 13.2 0.0 0.54 10.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KPA35241.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KPA35241.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KPA35241.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Lactonase PF10282.9 KPA35242.1 - 3e-70 237.2 0.0 4e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Glyco_hydro_18 PF00704.28 KPA35243.1 - 5.2e-14 52.7 0.0 1.3e-13 51.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 GFA PF04828.14 KPA35244.1 - 1.8e-11 44.2 0.4 1.8e-11 44.2 0.4 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF2889 PF11136.8 KPA35245.1 - 0.055 13.8 0.7 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2889) Paz_1 PF18349.1 KPA35246.1 - 0.089 12.8 0.8 0.24 11.4 0.8 1.7 1 0 0 1 1 1 0 PAZ domain DUF3723 PF12520.8 KPA35247.1 - 7.8e-24 84.2 0.0 1.1e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) HET PF06985.11 KPA35248.1 - 2.9e-16 60.1 0.4 5.2e-16 59.3 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cutinase PF01083.22 KPA35249.1 - 6.8e-21 75.0 0.1 7.9e-21 74.8 0.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPA35249.1 - 0.00055 19.5 0.1 0.00071 19.2 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.20 KPA35249.1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Zn_clus PF00172.18 KPA35250.1 - 7.8e-06 25.9 9.0 1.1e-05 25.4 9.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BLOC1_2 PF10046.9 KPA35250.1 - 0.048 13.9 0.0 0.072 13.4 0.0 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Shugoshin_N PF07558.11 KPA35250.1 - 0.05 13.5 0.2 0.18 11.7 0.3 1.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region PSI_integrin PF17205.3 KPA35250.1 - 0.073 12.8 5.1 0.14 12.0 5.1 1.5 1 0 0 1 1 1 0 Integrin plexin domain NPV_P10 PF05531.12 KPA35250.1 - 0.081 13.4 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4988 PF16378.5 KPA35250.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function Kelch_4 PF13418.6 KPA35251.1 - 1.4e-22 79.4 2.4 3.6e-13 49.3 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KPA35251.1 - 2.5e-17 62.7 2.0 2.1e-06 27.8 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KPA35251.1 - 1.1e-08 34.6 1.8 0.00012 21.6 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 KPA35251.1 - 0.00015 21.7 0.0 0.0094 15.9 0.1 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 KPA35251.1 - 0.0002 21.5 2.4 0.0093 16.2 0.1 3.8 3 1 1 4 4 4 1 Kelch motif Kelch_2 PF07646.15 KPA35251.1 - 0.00061 19.7 2.1 0.15 12.1 0.1 3.4 3 0 0 3 3 3 1 Kelch motif TauD PF02668.16 KPA35253.1 - 3.8e-12 46.6 0.0 5.2e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Tsp45I PF06300.12 KPA35254.1 - 0.0092 15.5 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 1 Tsp45I type II restriction enzyme Myb_DNA-bind_3 PF12776.7 KPA35254.1 - 0.03 15.3 0.7 0.086 13.8 0.5 1.8 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF4666 PF15697.5 KPA35254.1 - 0.074 13.7 0.4 0.16 12.6 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) eIF3_p135 PF12807.7 KPA35254.1 - 0.084 12.9 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 HsbA PF12296.8 KPA35255.1 - 1.6e-28 99.5 7.2 1.6e-28 99.5 7.2 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Prefoldin PF02996.17 KPA35256.1 - 0.1 12.5 0.2 0.27 11.2 0.2 1.7 1 0 0 1 1 1 0 Prefoldin subunit GreA_GreB_N PF03449.15 KPA35256.1 - 0.32 11.2 3.5 0.79 9.9 1.9 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal bZIP_2 PF07716.15 KPA35258.1 - 0.001 19.1 13.9 0.0017 18.4 13.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF2397 PF09660.10 KPA35258.1 - 0.012 14.6 2.2 0.016 14.1 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Fes1 PF08609.10 KPA35258.1 - 0.042 14.7 0.6 0.093 13.6 0.6 1.5 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 TBCC_N PF16752.5 KPA35258.1 - 0.2 12.1 6.1 0.33 11.4 6.1 1.2 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain DUF4551 PF15087.6 KPA35258.1 - 0.83 8.4 4.3 1.4 7.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) bZIP_1 PF00170.21 KPA35258.1 - 3 8.0 11.6 4.4 7.5 11.6 1.2 1 0 0 1 1 1 0 bZIP transcription factor Apolipoprotein PF01442.18 KPA35259.1 - 0.0013 18.6 9.8 0.0024 17.8 9.2 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 KPA35259.1 - 0.003 17.6 2.6 0.0067 16.5 2.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Vps54_N PF10475.9 KPA35259.1 - 0.034 13.4 3.6 0.048 13.0 3.6 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Prominin PF05478.11 KPA35259.1 - 0.039 11.9 1.3 0.048 11.6 1.3 1.1 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 KPA35259.1 - 0.11 12.1 5.1 0.13 11.8 5.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF725 PF05267.12 KPA35259.1 - 0.11 12.4 2.2 0.19 11.7 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) DUF2462 PF09495.10 KPA35259.1 - 0.14 12.9 2.9 0.14 12.9 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) Laminin_II PF06009.12 KPA35259.1 - 0.19 11.8 5.1 0.11 12.5 0.8 2.3 1 1 1 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.12 KPA35259.1 - 0.55 10.3 3.8 1.1 9.3 3.8 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KPA35259.1 - 2 8.7 4.5 1.9 8.8 1.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NACHT PF05729.12 KPA35260.1 - 9.4e-24 84.2 0.1 2e-23 83.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 KPA35260.1 - 1.6e-09 38.2 0.2 1.6e-09 38.2 0.2 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4509 PF14970.6 KPA35260.1 - 0.00046 20.2 0.5 0.0012 18.9 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4509) AAA_16 PF13191.6 KPA35260.1 - 0.0037 17.7 0.0 0.0098 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Mo25 PF08569.11 KPA35260.1 - 0.011 15.2 0.3 0.039 13.3 0.3 1.9 1 1 0 1 1 1 0 Mo25-like NACHT_N PF17100.5 KPA35260.1 - 0.013 15.4 0.1 0.033 14.0 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Pollen_Ole_e_I PF01190.17 KPA35260.1 - 0.055 13.9 0.5 0.19 12.1 0.1 2.0 2 0 0 2 2 2 0 Pollen proteins Ole e I like AAA_11 PF13086.6 KPA35260.1 - 0.062 13.1 2.2 0.19 11.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain Neil1-DNA_bind PF09292.10 KPA35260.1 - 0.12 12.3 0.2 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind Muted PF14942.6 KPA35260.1 - 2.4 8.5 9.2 0.51 10.7 4.6 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Zn_clus PF00172.18 KPA35263.1 - 2.9e-09 36.9 8.7 5.3e-09 36.1 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA35263.1 - 8e-09 34.9 0.6 2.1e-08 33.5 0.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3723 PF12520.8 KPA35264.1 - 7.3e-12 44.7 0.1 1.9e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) DUF3292 PF11696.8 KPA35267.1 - 3.2e-193 643.7 0.0 3.8e-193 643.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) HET PF06985.11 KPA35268.1 - 1.1e-37 129.6 0.5 3.1e-37 128.2 0.5 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ferric_reduct PF01794.19 KPA35270.1 - 1.5e-14 54.2 13.6 1.5e-14 54.2 13.6 2.4 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KPA35270.1 - 1.5e-05 25.0 0.0 3.9e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KPA35270.1 - 0.18 11.9 0.0 0.49 10.5 0.0 1.7 1 1 0 1 1 1 0 Ferric reductase NAD binding domain MLANA PF14991.6 KPA35270.1 - 0.36 11.1 3.3 1.7 8.9 2.6 2.4 2 1 0 2 2 2 0 Protein melan-A DUF4405 PF14358.6 KPA35270.1 - 1.4 9.5 12.8 0.42 11.2 0.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) HET PF06985.11 KPA35273.1 - 0.00035 21.0 0.0 0.00086 19.7 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1071 PF06378.11 KPA35273.1 - 0.01 15.4 0.1 0.47 10.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1071) p450 PF00067.22 KPA35274.1 - 1.9e-37 129.1 0.0 2.4e-35 122.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 PIF1 PF05970.14 KPA35276.1 - 4.4e-07 29.4 0.0 6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KPA35276.1 - 0.039 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain bacHORMA_2 PF18173.1 KPA35276.1 - 0.098 12.5 0.7 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial HORMA domain 2 Death PF00531.22 KPA35276.1 - 0.12 12.6 2.7 10 6.3 0.1 2.9 3 0 0 3 3 3 0 Death domain MFS_1 PF07690.16 KPA35277.1 - 6.4e-38 130.6 37.9 8.4e-38 130.2 37.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPA35277.1 - 2.8e-09 36.7 4.8 2.8e-09 36.7 4.8 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB YcxB PF14317.6 KPA35277.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 YcxB-like protein Inj_translocase PF16928.5 KPA35278.1 - 8.2e-05 22.2 1.1 0.00017 21.1 1.1 1.5 1 0 0 1 1 1 1 DNA/protein translocase of phage P22 injectosome Fungal_trans PF04082.18 KPA35279.1 - 6.8e-13 48.3 0.0 1.8e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA35279.1 - 1.7e-08 34.5 13.0 2.6e-08 33.8 13.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIF5_SNase_1 PF18187.1 KPA35280.1 - 0.16 11.7 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 TbRIF5 SNase domain 1 HisKA_3 PF07730.13 KPA35281.1 - 0.17 12.4 0.0 0.5 10.9 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase DUF2478 PF10649.9 KPA35282.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) Fungal_trans_2 PF11951.8 KPA35283.1 - 2.1e-34 119.0 2.4 3.3e-34 118.4 2.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA35283.1 - 1e-09 38.3 6.5 2e-09 37.4 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_3 PF01757.22 KPA35284.1 - 2.8e-15 56.2 5.4 3.7e-15 55.8 5.4 1.1 1 0 0 1 1 1 1 Acyltransferase family MFS_1 PF07690.16 KPA35285.1 - 2.1e-32 112.5 48.8 2.2e-22 79.5 28.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA35285.1 - 5.8e-08 32.0 31.5 9.4e-05 21.4 11.8 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter AA_permease_2 PF13520.6 KPA35286.1 - 1.1e-32 113.4 27.9 5.1e-29 101.4 14.0 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KPA35286.1 - 1.4e-15 56.9 18.0 3.4e-12 45.7 11.8 2.1 1 1 1 2 2 2 2 Amino acid permease HNH_2 PF13391.6 KPA35287.1 - 2.9e-13 49.7 0.1 8e-13 48.3 0.1 1.8 1 0 0 1 1 1 1 HNH endonuclease UbiA PF01040.18 KPA35288.1 - 9.1e-19 67.7 16.0 1.2e-18 67.3 16.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family p53-inducible11 PF14936.6 KPA35288.1 - 0.017 15.2 2.2 0.031 14.3 2.2 1.4 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 LapA_dom PF06305.11 KPA35288.1 - 0.33 10.8 9.1 0.17 11.7 3.3 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PRA1 PF03208.19 KPA35288.1 - 1.8 8.1 9.8 53 3.4 9.4 2.3 1 1 1 2 2 2 0 PRA1 family protein Meth_synt_2 PF01717.18 KPA35289.1 - 4.4e-09 36.1 0.0 9.5e-07 28.4 0.0 2.9 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KPA35289.1 - 0.037 13.6 0.0 0.12 11.8 0.0 1.9 3 0 0 3 3 3 0 Cobalamin-independent synthase, N-terminal domain Bac_chlorC PF02043.17 KPA35290.1 - 0.22 11.5 4.4 0.44 10.6 0.4 2.7 3 0 0 3 3 3 0 Bacteriochlorophyll C binding protein Peptidase_M13 PF01431.21 KPA35291.1 - 0.054 13.1 0.1 0.077 12.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M13 Methyltransf_23 PF13489.6 KPA35292.1 - 4.3e-17 62.4 0.0 6.6e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA35292.1 - 4.7e-11 43.2 0.0 1.4e-10 41.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA35292.1 - 2.6e-09 37.7 0.0 6.6e-07 30.0 0.0 3.7 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA35292.1 - 1.9e-08 34.8 0.0 3.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA35292.1 - 2.8e-06 27.2 0.0 0.0044 16.8 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KPA35292.1 - 0.00016 21.2 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KPA35292.1 - 0.0013 18.9 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KPA35292.1 - 0.0062 16.3 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 KPA35292.1 - 0.011 15.1 0.0 0.14 11.4 0.0 2.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KPA35292.1 - 0.026 13.9 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KPA35292.1 - 0.086 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KPA35292.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.12 KPA35292.1 - 0.097 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Fungal_trans_2 PF11951.8 KPA35293.1 - 4e-06 25.9 1.4 4.1e-06 25.9 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA35293.1 - 6.5e-06 26.2 7.9 1.2e-05 25.3 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_4 PF13637.6 KPA35294.1 - 1.1e-09 38.6 0.0 0.028 15.0 0.0 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA35294.1 - 3.1e-09 36.3 0.0 0.04 14.5 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 KPA35294.1 - 4.2e-07 30.5 0.0 0.043 14.4 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA35294.1 - 2.4e-06 27.7 0.0 0.002 18.4 0.0 3.7 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 KPA35294.1 - 0.00033 21.0 0.0 4.8 7.8 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeat WD40 PF00400.32 KPA35296.1 - 1.3e-05 25.8 2.1 0.24 12.3 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA35296.1 - 0.0044 17.3 0.0 1.1 9.5 0.0 3.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Erp_C PF06780.11 KPA35296.1 - 0.017 15.1 5.3 0.019 15.0 4.2 1.6 1 1 0 1 1 1 0 Erp protein C-terminus PQQ_3 PF13570.6 KPA35296.1 - 0.042 14.4 0.0 39 4.9 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain Flu_NS2 PF00601.19 KPA35296.1 - 0.85 10.0 7.6 1.1 9.6 5.1 2.2 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) Exonuc_VII_L PF02601.15 KPA35296.1 - 1.2 8.6 12.0 1.7 8.1 12.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 KPA35296.1 - 8.8 4.8 10.2 13 4.3 10.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KPA35296.1 - 9.3 6.3 17.7 16 5.5 17.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus InPase PF18823.1 KPA35297.1 - 0.076 12.7 0.4 0.18 11.5 0.2 1.7 1 1 1 2 2 2 0 Inorganic Pyrophosphatase Phage_int_SAM_3 PF14659.6 KPA35298.1 - 0.15 12.4 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Zn_clus PF00172.18 KPA35299.1 - 2e-10 40.6 7.2 3.5e-10 39.8 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA35299.1 - 0.0021 17.0 0.0 0.0027 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mucin PF01456.17 KPA35299.1 - 1.3 9.0 9.1 2 8.4 9.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein EamA PF00892.20 KPA35300.1 - 2.3e-14 53.7 10.6 2.3e-14 53.7 10.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family COesterase PF00135.28 KPA35301.1 - 6e-16 58.4 0.0 6.9e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family p450 PF00067.22 KPA35302.1 - 2e-36 125.8 0.0 2.1e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arteri_nsp7a PF16749.5 KPA35303.1 - 0.16 12.1 0.0 1.3 9.3 0.0 2.0 1 1 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha adh_short PF00106.25 KPA35304.1 - 2.4e-22 79.3 0.0 1e-18 67.5 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA35304.1 - 3.6e-13 49.6 0.0 1.5e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA35304.1 - 2.4e-06 27.6 0.0 3.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA35304.1 - 0.0031 17.0 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA35304.1 - 0.037 13.4 0.0 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase HTH_33 PF13592.6 KPA35305.1 - 0.087 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix p450 PF00067.22 KPA35306.1 - 5.2e-23 81.5 0.0 9.6e-23 80.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 DUF4635 PF15466.6 KPA35306.1 - 0.16 11.5 0.7 2.2 7.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) INCA1 PF15142.6 KPA35308.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 INCA1 AMP-binding PF00501.28 KPA35309.1 - 1.7e-20 73.0 0.0 2e-16 59.6 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme 53-BP1_Tudor PF09038.10 KPA35309.1 - 0.0063 16.5 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 Tumour suppressor p53-binding protein-1 Tudor GH3 PF03321.13 KPA35309.1 - 0.046 12.6 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 GH3 auxin-responsive promoter UvrD_C_2 PF13538.6 KPA35310.1 - 2.3e-09 37.0 0.0 5e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KPA35310.1 - 1e-07 31.8 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KPA35310.1 - 0.00027 20.4 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 KPA35310.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPA35310.1 - 0.0065 16.8 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_3 PF13366.6 KPA35310.1 - 0.019 15.3 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily EHN PF06441.12 KPA35311.1 - 9e-17 61.4 0.0 1.3e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPA35311.1 - 0.00092 18.9 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA35311.1 - 0.071 13.7 0.0 0.083 13.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hemocyanin_N PF03722.14 KPA35312.1 - 0.089 13.3 0.2 0.17 12.4 0.2 1.4 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain DUF4220 PF13968.6 KPA35312.1 - 0.12 11.7 0.2 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) HET PF06985.11 KPA35313.1 - 3e-43 147.6 0.0 5.6e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KPA35313.1 - 7.8e-08 32.8 0.0 1.5e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA35313.1 - 5.9e-06 26.7 0.1 0.00056 20.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA35313.1 - 0.00025 21.2 0.0 0.16 12.6 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KPA35313.1 - 0.0019 18.6 0.2 0.087 13.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KPA35313.1 - 0.0027 18.0 0.0 0.0073 16.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Glyco_hydro_3 PF00933.21 KPA35316.1 - 2.4e-31 109.3 0.0 4.8e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KPA35316.1 - 9.6e-06 25.7 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fungal_trans_2 PF11951.8 KPA35318.1 - 3.2e-08 32.8 0.1 4.4e-07 29.0 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF908 PF06012.12 KPA35318.1 - 0.002 17.6 0.0 0.0029 17.1 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) SNF PF00209.18 KPA35319.1 - 1.5e-06 27.2 0.2 1.5e-06 27.2 0.2 1.8 2 0 0 2 2 2 1 Sodium:neurotransmitter symporter family Omp_AT PF11557.8 KPA35320.1 - 0.16 10.9 0.2 0.22 10.4 0.2 1.1 1 0 0 1 1 1 0 Solitary outer membrane autotransporter beta-barrel domain HNH_2 PF13391.6 KPA35321.1 - 8.1e-10 38.7 0.1 2.8e-09 37.0 0.1 1.9 1 0 0 1 1 1 1 HNH endonuclease AHH PF14412.6 KPA35321.1 - 0.0033 17.5 0.0 0.0071 16.4 0.0 1.5 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Oxidored_FMN PF00724.20 KPA35323.1 - 1.4e-27 96.9 0.0 4.2e-27 95.3 0.0 1.7 2 0 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family HET PF06985.11 KPA35324.1 - 8.3e-37 126.8 1.1 1.5e-36 126.0 1.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Suf PF05843.14 KPA35325.1 - 2 8.3 5.9 4.2 7.3 5.9 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RIC3 PF15361.6 KPA35325.1 - 3.1 8.2 6.6 5.3 7.4 4.6 2.4 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Presenilin PF01080.17 KPA35325.1 - 3.6 6.3 8.0 6.6 5.4 8.0 1.3 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 KPA35326.1 - 1.1e-14 54.1 17.0 1.5e-09 37.2 12.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA35326.1 - 1.1e-07 31.1 9.8 1e-06 27.9 9.8 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter CorA PF01544.18 KPA35327.1 - 6.3e-08 32.3 0.1 1.1e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein VirB3 PF05101.13 KPA35327.1 - 0.019 15.2 1.4 0.038 14.2 1.4 1.5 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein HAD_2 PF13419.6 KPA35329.1 - 1.2e-18 67.8 0.0 2.4e-18 66.8 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA35329.1 - 2.1e-07 31.5 0.0 0.0019 18.6 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA35329.1 - 1e-05 25.5 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Se-cys_synth_N PF12390.8 KPA35329.1 - 0.019 15.2 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 Selenocysteine synthase N terminal Dioxygenase_C PF00775.21 KPA35330.1 - 5.4e-09 35.8 0.1 9e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase SpaA PF17802.1 KPA35330.1 - 0.11 12.9 0.4 0.3 11.4 0.2 1.9 2 0 0 2 2 2 0 Prealbumin-like fold domain DUF4711 PF15829.5 KPA35331.1 - 0.16 11.9 0.9 0.98 9.3 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4711) Hydrolase_4 PF12146.8 KPA35332.1 - 2e-19 69.8 0.0 2.7e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA35332.1 - 5e-19 69.8 1.2 6.1e-19 69.5 1.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA35332.1 - 4e-17 62.7 0.6 1.4e-13 51.1 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 KPA35332.1 - 4.6e-05 22.1 0.0 0.00069 18.2 0.0 2.0 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 KPA35332.1 - 0.0012 18.6 0.0 0.4 10.4 0.1 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KPA35332.1 - 0.0029 17.7 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KPA35332.1 - 0.021 14.3 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family NdhN PF11909.8 KPA35332.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N Tannase PF07519.11 KPA35333.1 - 9e-56 189.7 0.0 1.1e-55 189.5 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Glyco_hydro_7 PF00840.20 KPA35333.1 - 0.04 12.6 0.0 0.06 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 DUF3723 PF12520.8 KPA35334.1 - 3.6e-53 181.0 4.9 2.5e-31 109.0 0.0 3.6 3 1 1 4 4 4 3 Protein of unknown function (DUF3723) APG6_N PF17675.1 KPA35334.1 - 0.069 13.7 36.9 1 9.9 16.3 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region AAA_13 PF13166.6 KPA35334.1 - 0.76 8.3 17.1 1.1 7.8 17.1 1.2 1 0 0 1 1 1 0 AAA domain FIVAR PF07554.13 KPA35334.1 - 0.84 10.4 6.6 3.7 8.4 6.6 2.2 1 1 0 1 1 1 0 FIVAR domain Spc7 PF08317.11 KPA35334.1 - 0.84 8.5 30.2 0.39 9.6 26.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.6 KPA35334.1 - 0.85 9.3 25.6 0.64 9.7 13.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Exonuc_VII_L PF02601.15 KPA35334.1 - 0.96 8.9 17.8 1.8 8.1 17.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 KPA35334.1 - 2.4 8.2 16.4 4.1 7.5 6.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KPA35334.1 - 3.3 7.5 22.1 38 4.0 6.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CENP-K PF11802.8 KPA35334.1 - 3.6 7.1 19.4 6.8 6.2 19.4 1.5 1 0 0 1 1 1 0 Centromere-associated protein K DUF4407 PF14362.6 KPA35334.1 - 4.8 6.4 19.3 12 5.1 19.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 KPA35334.1 - 4.9 6.4 28.4 8.4 5.6 12.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.6 KPA35334.1 - 5.4 6.3 29.0 0.88 8.9 10.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 KPA35334.1 - 8.9 6.6 25.2 1.4 9.2 9.4 2.9 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF5393 PF17371.2 KPA35336.1 - 4.8 5.2 9.8 5.7 4.9 9.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) RTA1 PF04479.13 KPA35337.1 - 1e-59 201.6 14.5 1.5e-59 201.1 14.5 1.2 1 0 0 1 1 1 1 RTA1 like protein EphA2_TM PF14575.6 KPA35337.1 - 0.057 14.3 1.5 0.11 13.4 0.7 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glyco_hydro_12 PF01670.16 KPA35339.1 - 1.1e-65 221.6 11.5 1.3e-65 221.4 11.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 WW PF00397.26 KPA35342.1 - 0.003 17.6 7.1 0.0077 16.3 7.1 1.8 1 0 0 1 1 1 1 WW domain Gram_pos_anchor PF00746.21 KPA35342.1 - 0.0045 16.9 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 LPXTG cell wall anchor motif DUF2076 PF09849.9 KPA35342.1 - 0.084 12.9 0.2 0.084 12.9 0.2 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF3295 PF11702.8 KPA35344.1 - 1.4e-112 377.6 28.0 1.1e-110 371.4 28.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KPA35344.1 - 1.9e-10 40.4 0.7 4.3e-10 39.2 0.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF4135 PF13575.6 KPA35346.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) MFS_1 PF07690.16 KPA35347.1 - 7.9e-33 113.8 25.4 1.1e-32 113.3 25.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA35347.1 - 2.1e-07 30.2 3.6 3.4e-07 29.5 3.2 1.4 1 1 0 1 1 1 1 MFS_1 like family DUF3951 PF13131.6 KPA35347.1 - 0.099 12.9 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) ADH_N PF08240.12 KPA35348.1 - 3.6e-22 78.3 1.5 5.7e-22 77.7 1.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA35348.1 - 1.7e-20 73.3 0.1 3.3e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA35348.1 - 0.00025 22.1 0.0 0.00068 20.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase CFC PF09443.10 KPA35348.1 - 1.3 8.9 7.6 0.33 10.8 3.9 2.0 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Zn_clus PF00172.18 KPA35349.1 - 2.9e-07 30.5 10.1 5.4e-07 29.6 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA35349.1 - 0.018 14.1 0.3 0.03 13.4 0.3 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA35350.1 - 4.1e-09 36.4 10.7 7.2e-09 35.6 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.6 KPA35351.1 - 0.00096 20.2 0.0 0.0013 19.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KPA35351.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Aconitase_2_N PF06434.13 KPA35352.1 - 0.095 12.3 0.1 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Aconitate hydratase 2 N-terminus p450 PF00067.22 KPA35353.1 - 4.6e-52 177.3 0.0 5.3e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 KPA35355.1 - 1.8e-46 158.9 35.2 2.4e-46 158.5 35.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA35355.1 - 5.6e-15 54.9 29.1 5.6e-15 54.9 29.1 2.6 2 1 0 2 2 2 1 Amino acid permease VIT1 PF01988.19 KPA35356.1 - 1.6e-60 204.7 0.3 1.8e-60 204.5 0.3 1.0 1 0 0 1 1 1 1 VIT family Phosphoesterase PF04185.14 KPA35357.1 - 1.6e-19 70.3 0.3 5.9e-19 68.5 0.3 1.7 1 1 0 1 1 1 1 Phosphoesterase family NACHT PF05729.12 KPA35358.1 - 1.1e-08 35.1 1.0 8e-08 32.4 0.2 2.7 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KPA35358.1 - 1.6e-06 28.6 0.0 8.6e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 KPA35358.1 - 0.00086 18.7 0.1 0.0019 17.6 0.1 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NB-ARC PF00931.22 KPA35358.1 - 0.0013 17.9 0.0 0.0078 15.4 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 KPA35358.1 - 0.0024 18.3 0.0 0.0073 16.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KPA35358.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea APS_kinase PF01583.20 KPA35358.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KPA35358.1 - 0.024 15.2 0.0 0.099 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KPA35358.1 - 0.055 13.8 0.0 0.21 11.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KPA35358.1 - 0.11 12.2 0.3 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KPA35358.1 - 0.12 11.6 0.0 0.32 10.2 0.0 1.7 1 0 0 1 1 1 0 KAP family P-loop domain RTA1 PF04479.13 KPA35359.1 - 5.1e-63 212.4 11.4 5.1e-63 212.4 11.4 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF2755 PF10954.8 KPA35359.1 - 0.0036 17.2 1.0 1 9.4 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2755) TraQ PF09679.10 KPA35359.1 - 0.42 10.6 0.1 0.42 10.6 0.1 2.8 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin chaperone (TraQ) DAO PF01266.24 KPA35360.1 - 1.3e-34 120.4 0.0 1.4e-34 120.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA35360.1 - 5e-08 32.5 0.0 0.0049 16.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA35360.1 - 1.2e-07 31.2 0.2 0.0032 16.6 0.0 2.8 2 1 1 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KPA35360.1 - 9.3e-07 28.3 0.0 1.9e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPA35360.1 - 0.00015 22.0 0.1 0.00065 19.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KPA35360.1 - 0.00033 20.1 0.0 0.00055 19.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family Trp_halogenase PF04820.14 KPA35360.1 - 0.0048 15.8 0.4 0.017 14.0 0.1 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 KPA35360.1 - 0.0057 17.2 0.0 0.03 14.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KPA35360.1 - 0.056 13.5 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KPA35360.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 KPA35360.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 KPA35360.1 - 0.14 12.6 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KPA35360.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KPA35360.1 - 0.19 11.7 0.1 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KPA35360.1 - 0.22 11.4 0.0 1 9.2 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.28 KPA35361.1 - 9.6e-19 67.3 0.0 1.2e-16 60.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.13 KPA35361.1 - 0.12 11.2 0.0 0.25 10.2 0.0 1.4 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Amidohydro_3 PF07969.11 KPA35362.1 - 1.7e-06 27.8 0.1 2.4e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KPA35362.1 - 0.0037 16.6 0.2 0.005 16.2 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Ferric_reduct PF01794.19 KPA35363.1 - 1.4e-10 41.4 4.3 1.4e-10 41.4 4.3 2.5 2 1 0 2 2 2 2 Ferric reductase like transmembrane component DUF4405 PF14358.6 KPA35363.1 - 0.0039 17.7 2.2 0.0039 17.7 2.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4405) DUF3341 PF11821.8 KPA35363.1 - 2.4 7.8 8.4 4.5 6.9 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3341) Ctr PF04145.15 KPA35364.1 - 2.3e-23 83.5 7.3 4.5e-23 82.5 7.3 1.5 1 1 0 1 1 1 1 Ctr copper transporter family DUF4818 PF16089.5 KPA35364.1 - 0.013 16.0 1.1 0.019 15.4 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4818) Dimer_Tnp_hAT PF05699.14 KPA35365.1 - 3.4e-15 55.6 0.0 1.6e-14 53.5 0.0 2.2 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region NB-ARC PF00931.22 KPA35367.1 - 2.1e-11 43.5 0.0 0.00011 21.5 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 KPA35367.1 - 8e-08 32.9 0.0 2.6e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KPA35367.1 - 8.9e-07 29.1 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KPA35367.1 - 0.00041 20.6 0.0 0.0032 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KPA35367.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KPA35367.1 - 0.11 12.3 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KPA35368.1 - 3.7e-26 92.1 0.0 1.5e-15 57.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 KPA35368.1 - 1.3e-09 38.1 13.0 1.4e-08 34.8 1.5 4.2 4 0 0 4 4 4 2 AAA lid domain AAA_30 PF13604.6 KPA35368.1 - 5.7e-07 29.4 0.9 0.028 14.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 KPA35368.1 - 6.3e-07 29.0 0.0 0.0039 16.6 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KPA35368.1 - 8.1e-07 29.4 4.8 0.91 9.8 0.0 5.5 4 2 1 5 5 5 3 AAA domain AAA_5 PF07728.14 KPA35368.1 - 9.3e-06 25.7 0.1 0.073 13.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KPA35368.1 - 1.1e-05 25.2 0.0 0.15 11.8 0.0 3.2 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KPA35368.1 - 8.1e-05 23.0 0.0 0.55 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.6 KPA35368.1 - 0.00013 22.4 2.8 0.069 13.5 0.1 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KPA35368.1 - 0.00014 22.1 3.8 0.04 14.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KPA35368.1 - 0.00036 20.9 0.5 1.7 9.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 KPA35368.1 - 0.00045 20.0 0.3 0.55 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KPA35368.1 - 0.0011 18.7 0.0 1.5 8.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KPA35368.1 - 0.0014 18.4 0.1 0.66 9.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 KPA35368.1 - 0.0027 17.9 5.1 1.5 9.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KPA35368.1 - 0.0041 17.7 6.6 1.3 9.5 0.0 3.9 3 1 1 4 4 4 2 AAA domain AAA_7 PF12775.7 KPA35368.1 - 0.0079 15.7 0.0 3.2 7.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 KPA35368.1 - 0.019 14.7 0.0 3.5 7.3 0.0 3.1 2 1 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KPA35368.1 - 0.022 14.7 0.2 7.6 6.4 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 KPA35368.1 - 0.036 13.8 10.0 0.39 10.5 0.0 3.7 3 1 0 3 3 3 0 AAA domain SRP54 PF00448.22 KPA35368.1 - 0.038 13.6 0.1 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KPA35368.1 - 0.26 11.8 8.6 1.2 9.6 2.9 3.5 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 KPA35368.1 - 1 8.5 7.8 6.5 5.9 0.0 3.9 3 1 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 KPA35368.1 - 1.5 9.3 10.4 5.4 7.4 0.2 3.5 3 0 0 3 3 3 0 AAA domain SKI PF01202.22 KPA35368.1 - 3 7.9 5.7 8.7 6.5 0.0 3.5 3 0 0 3 3 2 0 Shikimate kinase Zn_clus PF00172.18 KPA35369.1 - 1.8e-08 34.3 8.3 2.7e-08 33.8 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zinc_ribbon_6 PF14599.6 KPA35369.1 - 0.03 14.3 1.7 0.057 13.4 1.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon zf-C2H2 PF00096.26 KPA35370.1 - 0.0026 18.1 2.7 0.0061 17.0 0.4 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA35370.1 - 0.0093 16.7 3.4 0.029 15.2 0.2 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KPA35370.1 - 0.057 13.4 0.2 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4629 PF15442.6 KPA35370.1 - 0.078 13.2 1.8 0.13 12.5 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) zf-MYST PF17772.1 KPA35370.1 - 0.2 11.3 0.2 5.4 6.7 0.0 2.6 2 1 1 3 3 3 0 MYST family zinc finger domain Pkinase_Tyr PF07714.17 KPA35371.1 - 4.9e-12 45.7 0.0 9e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KPA35371.1 - 1.7e-11 44.0 0.0 2.2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KPA35373.1 - 1.4e-128 429.2 0.2 1.7e-128 428.9 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KPA35373.1 - 5e-09 35.9 0.0 9.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA35373.1 - 0.0079 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPA35373.1 - 0.036 13.4 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KR PF08659.10 KPA35374.1 - 7.2e-56 188.9 1.5 1.9e-55 187.6 0.2 2.2 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 KPA35374.1 - 6.2e-16 58.6 0.1 1.9e-15 57.0 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KPA35374.1 - 2e-12 47.0 0.4 1.7e-10 40.7 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 KPA35374.1 - 6.3e-09 36.1 0.0 2.4e-08 34.2 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 KPA35374.1 - 9.7e-09 36.4 0.0 2.5e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KPA35374.1 - 0.00035 20.2 0.0 0.00035 20.2 0.0 1.9 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KPA35374.1 - 0.0044 16.9 0.1 0.023 14.6 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain YAcAr PF10686.9 KPA35374.1 - 0.053 13.5 0.1 17 5.4 0.1 2.6 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family Polysacc_synt_2 PF02719.15 KPA35374.1 - 0.076 12.1 0.0 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CbiG_N PF11760.8 KPA35374.1 - 2.2 8.3 4.4 0.49 10.4 0.6 1.9 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal Sugar_tr PF00083.24 KPA35375.1 - 4.1e-09 35.8 1.5 4.8e-09 35.6 1.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA35375.1 - 0.00081 18.4 5.9 0.0011 18.0 5.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily PspA_IM30 PF04012.12 KPA35376.1 - 1.8e-05 24.4 3.0 2.6e-05 23.9 3.0 1.2 1 0 0 1 1 1 1 PspA/IM30 family ATG16 PF08614.11 KPA35376.1 - 0.00069 19.9 4.2 0.0012 19.1 4.2 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KPA35376.1 - 0.0012 17.8 1.5 0.0018 17.3 1.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DivIC PF04977.15 KPA35376.1 - 0.0033 17.2 4.8 0.0033 17.2 4.8 1.6 2 0 0 2 2 1 1 Septum formation initiator FlaC_arch PF05377.11 KPA35376.1 - 0.0049 17.2 2.1 0.026 14.9 0.6 2.5 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) SlyX PF04102.12 KPA35376.1 - 0.0073 16.9 5.2 0.019 15.6 5.1 1.8 1 1 0 1 1 1 1 SlyX Taxilin PF09728.9 KPA35376.1 - 0.01 15.0 3.1 0.014 14.6 3.1 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Tropomyosin_1 PF12718.7 KPA35376.1 - 0.015 15.5 2.6 0.024 14.8 2.6 1.2 1 0 0 1 1 1 0 Tropomyosin like TMF_DNA_bd PF12329.8 KPA35376.1 - 0.018 15.0 2.2 0.033 14.2 2.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc29 PF17082.5 KPA35376.1 - 0.018 14.9 0.4 0.027 14.3 0.4 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 ZapB PF06005.12 KPA35376.1 - 0.018 15.5 2.4 0.031 14.7 2.4 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Fib_alpha PF08702.10 KPA35376.1 - 0.02 15.1 0.1 0.045 13.9 0.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF573 PF04504.14 KPA35376.1 - 0.02 15.5 0.6 0.15 12.8 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF573 APG6_N PF17675.1 KPA35376.1 - 0.026 15.1 5.0 0.04 14.5 5.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region BLOC1_2 PF10046.9 KPA35376.1 - 0.033 14.5 3.7 0.057 13.7 2.2 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.12 KPA35376.1 - 0.044 12.0 1.2 0.063 11.4 1.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Med9 PF07544.13 KPA35376.1 - 0.054 13.6 2.6 0.11 12.6 2.6 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_2 PF07716.15 KPA35376.1 - 0.06 13.4 4.9 0.042 13.9 3.1 1.8 1 1 0 1 1 1 0 Basic region leucine zipper Herpes_UL6 PF01763.16 KPA35376.1 - 0.094 11.2 0.3 0.13 10.7 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like ADIP PF11559.8 KPA35376.1 - 0.1 12.7 4.1 0.17 12.0 4.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KPA35376.1 - 0.27 11.9 0.9 0.54 10.9 0.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF5595 PF18077.1 KPA35376.1 - 0.29 11.2 1.5 0.54 10.4 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) TMPIT PF07851.13 KPA35376.1 - 0.35 10.1 0.4 0.51 9.5 0.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein UL42 PF17638.2 KPA35376.1 - 0.59 10.1 6.4 1.2 9.1 6.4 1.4 1 0 0 1 1 1 0 HCMV UL42 XhlA PF10779.9 KPA35376.1 - 2 8.7 4.5 7.3 6.9 1.5 2.6 1 1 1 2 2 2 0 Haemolysin XhlA DUF4140 PF13600.6 KPA35376.1 - 8.4 6.9 9.4 3.6 8.1 4.1 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Pro_isomerase PF00160.21 KPA35377.1 - 1.6e-48 164.9 0.0 1.9e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pyr_redox_2 PF07992.14 KPA35381.1 - 4.4e-18 65.5 0.0 4.8e-10 39.2 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Cupin_1 PF00190.22 KPA35381.1 - 7.2e-16 58.1 0.0 1.8e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KPA35381.1 - 0.0017 18.0 0.0 0.0052 16.5 0.0 1.9 1 1 0 1 1 1 1 Cupin domain SWIRM-assoc_2 PF16496.5 KPA35382.1 - 0.12 11.2 7.0 0.18 10.6 7.0 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Cation_ATPase_C PF00689.21 KPA35384.1 - 3.8e-13 49.6 0.5 5e-13 49.2 0.5 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus MARVEL PF01284.23 KPA35385.1 - 7.3e-10 39.0 7.1 2.5e-09 37.3 7.1 1.8 1 1 0 1 1 1 1 Membrane-associating domain VIT1 PF01988.19 KPA35385.1 - 0.037 13.9 0.7 0.053 13.4 0.7 1.3 1 0 0 1 1 1 0 VIT family ATPase_gene1 PF09527.10 KPA35385.1 - 0.11 12.6 0.3 0.11 12.6 0.3 2.6 2 1 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter HET PF06985.11 KPA35388.1 - 0.00078 19.8 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADK PF00406.22 KPA35388.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Adenylate kinase TPT PF03151.16 KPA35389.1 - 6.3e-09 35.6 15.5 7.9e-09 35.3 15.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family adh_short PF00106.25 KPA35392.1 - 3e-29 101.9 0.1 3.8e-29 101.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA35392.1 - 2.5e-20 73.0 0.1 3e-19 69.5 0.1 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA35392.1 - 1.6e-10 41.2 0.0 2.1e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA35392.1 - 8.1e-06 25.2 0.0 9.6e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPA35392.1 - 2.5e-05 23.9 0.1 6.8e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Alpha-amylase PF00128.24 KPA35392.1 - 0.0021 17.7 0.0 0.0027 17.3 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain NAD_binding_4 PF07993.12 KPA35392.1 - 0.0028 16.9 0.0 0.0069 15.6 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KPA35392.1 - 0.0069 15.8 0.4 0.16 11.3 0.4 2.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 KPA35392.1 - 0.18 11.6 1.0 0.37 10.6 1.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glycoamylase PF10091.9 KPA35393.1 - 0.03 13.9 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative glucoamylase MLTD_N PF06474.12 KPA35393.1 - 0.15 12.2 0.1 0.37 11.0 0.1 1.7 1 0 0 1 1 1 0 MltD lipid attachment motif AAA_21 PF13304.6 KPA35393.1 - 0.16 11.7 0.0 18 5.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Peptidase_M20 PF01546.28 KPA35394.1 - 4.2e-08 33.2 0.1 5.8e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPA35394.1 - 0.00069 19.5 0.0 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 Peptidase dimerisation domain IBR PF01485.21 KPA35395.1 - 4.6e-18 65.2 17.5 4e-12 46.2 1.7 5.6 5 1 1 6 6 6 2 IBR domain, a half RING-finger domain TPR_MLP1_2 PF07926.12 KPA35395.1 - 0.0032 17.5 1.2 0.005 16.9 1.2 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PI3K_P85_iSH2 PF16454.5 KPA35395.1 - 0.0076 15.9 3.6 0.013 15.1 3.6 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Atg14 PF10186.9 KPA35395.1 - 0.022 13.9 3.6 0.038 13.1 3.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_CLD_2 PF14197.6 KPA35395.1 - 0.028 14.5 2.9 0.07 13.2 2.9 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 BRE1 PF08647.11 KPA35395.1 - 0.045 13.8 2.4 0.088 12.9 2.4 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Tup_N PF08581.10 KPA35395.1 - 0.17 12.2 2.5 0.35 11.2 2.5 1.6 1 0 0 1 1 1 0 Tup N-terminal CENP-F_leu_zip PF10473.9 KPA35395.1 - 0.45 10.5 5.5 0.82 9.7 5.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 KPA35395.1 - 1.3 9.4 4.8 2.3 8.6 4.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FAD_binding_4 PF01565.23 KPA35397.1 - 1.8e-23 82.8 0.2 2.2e-23 82.5 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KPA35399.1 - 3.2e-96 323.0 0.1 3.7e-96 322.8 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPA35399.1 - 3.1e-07 30.5 0.0 1.1e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA35399.1 - 2.3e-06 27.4 1.1 3.3e-05 23.7 0.7 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA35399.1 - 4.8e-06 25.5 1.5 0.00094 18.0 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 KPA35399.1 - 9.3e-06 25.1 0.3 0.00029 20.2 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA35399.1 - 7.3e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KPA35399.1 - 0.00015 21.0 0.0 0.00015 21.0 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KPA35399.1 - 0.00071 18.9 0.1 0.0018 17.6 0.1 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KPA35399.1 - 0.0026 17.2 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPA35399.1 - 0.0049 16.0 0.1 0.0097 15.0 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KPA35399.1 - 0.034 13.4 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 KPA35400.1 - 6.1e-86 289.1 17.7 7.2e-86 288.8 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA35400.1 - 1e-29 103.6 27.1 8.6e-23 80.8 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA35400.1 - 1.2e-07 30.6 1.0 1.2e-07 30.6 1.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KPA35400.1 - 1.3e-06 27.3 22.0 7.2e-06 24.8 2.5 3.6 2 2 2 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.7 KPA35400.1 - 0.016 14.1 4.4 0.062 12.1 2.0 2.5 1 1 1 2 2 2 0 MFS_1 like family ADH_zinc_N PF00107.26 KPA35401.1 - 5.3e-09 36.1 0.0 9.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA35401.1 - 0.013 15.3 0.1 0.078 12.9 0.0 2.2 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain Hydrophobin_2 PF06766.11 KPA35402.1 - 1.8e-09 37.4 1.8 3.2e-09 36.6 1.8 1.4 1 1 0 1 1 1 1 Fungal hydrophobin Pyr_redox_2 PF07992.14 KPA35403.1 - 7.7e-27 94.3 3.8 2.6e-23 82.7 2.2 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA35403.1 - 9.8e-14 51.7 2.0 4.5e-13 49.5 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA35403.1 - 3e-06 26.6 0.0 4.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KPA35403.1 - 2.7e-05 23.2 2.1 0.17 10.7 0.0 3.1 2 1 1 3 3 3 3 Tryptophan halogenase DAO PF01266.24 KPA35403.1 - 8.8e-05 22.2 2.8 0.18 11.4 0.0 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KPA35403.1 - 0.00014 21.2 2.9 0.022 14.0 0.7 2.1 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KPA35403.1 - 0.00029 20.2 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA35403.1 - 0.035 12.8 1.4 0.13 10.9 0.2 2.3 2 1 1 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 KPA35403.1 - 0.049 12.7 0.1 0.095 11.7 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein DUF2605 PF10792.9 KPA35403.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) DUF424 PF04242.13 KPA35403.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF424) GIDA PF01134.22 KPA35403.1 - 0.16 11.0 4.3 0.91 8.5 2.0 2.6 2 1 1 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KPA35403.1 - 0.17 11.9 2.7 1.4 8.9 0.0 2.8 2 1 1 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KPA35403.1 - 0.21 10.9 2.8 2.6 7.3 0.8 2.4 1 1 1 2 2 2 0 FAD dependent oxidoreductase DUF3180 PF11377.8 KPA35403.1 - 2.8 8.1 9.0 0.64 10.2 3.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) MFS_1 PF07690.16 KPA35404.1 - 0.00012 21.2 15.2 0.00022 20.3 15.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_23 PF13489.6 KPA35405.1 - 5.2e-16 58.9 0.0 8.9e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA35405.1 - 9.3e-08 32.7 0.0 2.3e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA35405.1 - 1.2e-05 25.1 0.0 6.3e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA35405.1 - 0.00065 20.3 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA35405.1 - 0.0099 16.6 0.1 0.04 14.6 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KPA35405.1 - 0.021 14.2 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Holin_BhlA PF10960.8 KPA35405.1 - 0.15 12.1 0.1 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 BhlA holin family PP-binding PF00550.25 KPA35406.1 - 3e-08 33.9 0.0 4.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site TauD PF02668.16 KPA35407.1 - 2.3e-58 198.1 0.4 2.9e-58 197.8 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HET PF06985.11 KPA35408.1 - 1.3e-27 97.0 0.2 1.3e-27 97.0 0.2 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) PPP4R2 PF09184.11 KPA35408.1 - 0.11 12.1 11.4 0.2 11.2 11.4 1.4 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 KPA35408.1 - 0.11 11.8 14.5 0.19 11.1 14.5 1.4 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 KPA35408.1 - 0.12 12.4 9.8 0.18 11.8 9.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 KPA35408.1 - 0.13 11.6 15.8 0.23 10.7 15.8 1.4 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KPA35408.1 - 0.55 10.3 8.6 1.2 9.1 8.6 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 KPA35408.1 - 0.74 8.0 18.5 0.99 7.5 18.5 1.2 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 KPA35408.1 - 1.3 8.1 17.8 2.1 7.4 17.8 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RPN2_C PF18004.1 KPA35408.1 - 1.7 8.5 10.6 3.4 7.5 9.4 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pox_Ag35 PF03286.14 KPA35408.1 - 4.3 7.1 12.9 8.8 6.1 12.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 KPA35408.1 - 6.9 5.3 5.2 10 4.8 5.2 1.2 1 0 0 1 1 1 0 Presenilin TFB6 PF17110.5 KPA35408.1 - 7.8 6.2 9.8 16 5.2 9.8 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Tim54 PF11711.8 KPA35408.1 - 10 4.8 9.2 18 4.0 9.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spidroin_MaSp PF11260.8 KPA35411.1 - 0.034 14.4 1.7 0.063 13.6 1.7 1.4 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 eIF3_N PF09440.10 KPA35411.1 - 0.095 13.1 0.4 0.11 12.9 0.4 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain FSA_C PF10479.9 KPA35411.1 - 1.7 6.6 7.9 1.9 6.5 7.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus p450 PF00067.22 KPA35412.1 - 1.2e-53 182.5 0.0 1.4e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3425 PF11905.8 KPA35413.1 - 8.3e-23 80.7 1.1 1.8e-22 79.6 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KPA35413.1 - 0.01 15.9 7.9 0.027 14.6 7.8 1.8 1 1 0 1 1 1 0 bZIP transcription factor tRNA-synt_1c PF00749.21 KPA35413.1 - 0.11 11.4 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain PP-binding PF00550.25 KPA35414.1 - 4.4e-08 33.3 0.0 6.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 KPA35415.1 - 4.3e-17 62.5 0.0 7.3e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA35415.1 - 8.1e-11 42.5 0.0 1.8e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA35415.1 - 3.4e-07 30.2 0.0 1.8e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA35415.1 - 7.5e-06 26.5 0.0 1.7e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA35415.1 - 0.0003 21.5 0.0 0.0014 19.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KPA35415.1 - 0.0012 18.4 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KPA35415.1 - 0.0084 15.6 0.0 0.025 14.1 0.0 1.8 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KPA35415.1 - 0.025 13.9 0.0 0.046 13.0 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KPA35415.1 - 0.046 13.3 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain GidB PF02527.15 KPA35415.1 - 0.28 10.5 0.4 2.8 7.2 0.0 2.6 4 0 0 4 4 4 0 rRNA small subunit methyltransferase G Arginosuc_synth PF00764.19 KPA35417.1 - 2e-06 27.4 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase Methyltransf_23 PF13489.6 KPA35418.1 - 7.1e-28 97.5 0.0 1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA35418.1 - 1e-10 42.2 0.0 2.5e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA35418.1 - 1.3e-09 38.0 0.0 1.7e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA35418.1 - 1.2e-08 35.5 0.0 3.2e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA35418.1 - 1.2e-06 29.2 0.0 1e-05 26.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KPA35418.1 - 0.00012 22.2 0.0 0.00016 21.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KPA35418.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KPA35418.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 KPA35418.1 - 0.02 14.3 0.0 0.047 13.1 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KPA35418.1 - 0.077 12.3 0.0 0.27 10.5 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase p450 PF00067.22 KPA35419.1 - 1.5e-35 122.9 0.0 1.4e-34 119.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 RAP1 PF07218.11 KPA35420.1 - 0.011 14.1 1.6 0.013 13.8 1.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 KPA35420.1 - 0.014 14.0 2.3 0.018 13.6 2.3 1.0 1 0 0 1 1 1 0 Macoilin family TFIIF_alpha PF05793.12 KPA35420.1 - 0.32 9.5 7.6 0.44 9.1 7.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Peptidase_S64 PF08192.11 KPA35420.1 - 1.5 7.2 3.0 1.9 6.9 3.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 p450 PF00067.22 KPA35421.1 - 8.9e-35 120.3 0.0 1.3e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF5510 PF17629.2 KPA35421.1 - 0.13 12.2 0.2 0.47 10.4 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5510) IFT46_B_C PF12317.8 KPA35421.1 - 0.13 11.9 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Dimer_Tnp_hAT PF05699.14 KPA35422.1 - 3.5e-16 58.8 0.1 1e-15 57.3 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 KPA35422.1 - 0.0043 17.0 0.5 0.0099 15.9 0.5 1.6 1 0 0 1 1 1 1 BED zinc finger Helitron_like_N PF14214.6 KPA35423.1 - 1.1e-07 32.3 0.8 1.7e-07 31.7 0.8 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus FA_hydroxylase PF04116.13 KPA35425.1 - 0.33 11.3 2.3 1.4 9.3 0.4 2.2 2 1 1 3 3 3 0 Fatty acid hydroxylase superfamily E1-E2_ATPase PF00122.20 KPA35426.1 - 2.2e-45 154.4 8.2 6.9e-45 152.8 3.3 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KPA35426.1 - 4e-24 86.1 1.7 7.7e-24 85.1 1.7 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KPA35426.1 - 1.1e-06 29.0 0.0 4.6e-06 27.0 0.0 2.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fungal_trans PF04082.18 KPA35427.1 - 3.9e-26 91.7 1.4 5.6e-26 91.2 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peroxidase_2 PF01328.17 KPA35428.1 - 3e-41 142.0 0.0 4.3e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Abhydrolase_1 PF00561.20 KPA35432.1 - 1.2e-17 64.4 0.1 1.5e-17 64.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA35432.1 - 6.4e-10 40.0 0.3 7.6e-10 39.8 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA35432.1 - 4.3e-09 36.0 0.0 5e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KPA35432.1 - 0.00058 18.6 0.0 0.00081 18.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family AXE1 PF05448.12 KPA35432.1 - 0.005 15.6 0.0 0.0063 15.2 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hyccin PF09790.9 KPA35432.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Hyccin Abhydrolase_2 PF02230.16 KPA35432.1 - 0.19 11.5 0.0 0.69 9.7 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TrkH PF02386.16 KPA35433.1 - 2.7e-112 375.8 9.3 3.9e-74 249.9 5.2 2.0 1 1 1 2 2 2 2 Cation transport protein RseA_C PF03873.13 KPA35434.1 - 0.0041 17.3 0.6 0.038 14.2 0.4 2.5 2 0 0 2 2 2 1 Anti sigma-E protein RseA, C-terminal domain TRAP_alpha PF03896.16 KPA35434.1 - 0.064 12.4 1.5 0.12 11.5 1.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF262 PF03235.14 KPA35434.1 - 2.7 8.1 5.0 13 5.8 5.1 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF262 Herpes_UL92 PF03048.14 KPA35435.1 - 0.0057 16.5 0.3 0.0061 16.4 0.3 1.2 1 0 0 1 1 1 1 UL92 family KR PF08659.10 KPA35436.1 - 6.7e-57 192.3 0.0 2e-56 190.7 0.0 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KPA35436.1 - 1.5e-10 40.9 0.0 3.1e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 KPA35436.1 - 1.7e-05 24.6 0.3 3.7e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KPA35436.1 - 6.2e-05 23.3 0.0 0.00017 21.8 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KPA35436.1 - 0.00014 21.5 0.0 0.00034 20.2 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 KPA35436.1 - 0.0009 19.2 0.3 0.054 13.5 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA35436.1 - 0.0018 19.3 0.0 0.0059 17.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Dimer_Tnp_hAT PF05699.14 KPA35437.1 - 7.2e-13 48.1 0.1 1.8e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region VapB_antitoxin PF09957.9 KPA35437.1 - 0.075 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB PAD PF03068.15 KPA35438.1 - 8e-123 410.3 0.0 1.1e-122 409.9 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Ribonuc_L-PSP PF01042.21 KPA35438.1 - 0.076 13.0 0.0 7 6.7 0.0 2.3 2 0 0 2 2 2 0 Endoribonuclease L-PSP EF-hand_5 PF13202.6 KPA35438.1 - 0.14 11.7 0.2 0.35 10.5 0.2 1.7 1 0 0 1 1 1 0 EF hand NmrA PF05368.13 KPA35439.1 - 2.2e-22 79.8 0.0 3.1e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA35439.1 - 6.3e-12 45.8 0.0 1e-11 45.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPA35439.1 - 0.00016 21.9 0.0 0.00063 20.0 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KPA35439.1 - 0.00083 19.8 0.2 0.0018 18.7 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KPA35439.1 - 0.0023 18.1 0.0 0.0055 16.8 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 KPA35439.1 - 0.032 15.0 0.0 0.064 14.0 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GFO_IDH_MocA PF01408.22 KPA35439.1 - 0.034 15.0 0.0 0.058 14.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_4 PF07993.12 KPA35439.1 - 0.036 13.2 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein TPR_11 PF13414.6 KPA35439.1 - 0.09 12.5 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 TPR repeat 3Beta_HSD PF01073.19 KPA35439.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CN_hydrolase PF00795.22 KPA35440.1 - 1.3e-19 70.6 0.0 1.8e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ank_2 PF12796.7 KPA35441.1 - 1e-70 234.3 10.3 3.4e-14 53.2 0.2 8.1 4 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA35441.1 - 1.2e-63 210.7 14.1 8.1e-09 35.9 0.0 11.5 8 3 3 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA35441.1 - 5.3e-58 192.3 16.7 2.5e-10 40.4 0.1 11.7 5 3 8 13 13 13 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA35441.1 - 1.3e-51 166.5 10.9 0.0021 18.4 0.0 15.2 15 0 0 15 15 15 12 Ankyrin repeat Ank PF00023.30 KPA35441.1 - 3.6e-36 122.0 18.8 0.0076 16.7 0.0 13.4 14 0 0 14 14 14 10 Ankyrin repeat HET PF06985.11 KPA35442.1 - 1.3e-21 77.4 0.1 2.3e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.13 KPA35443.1 - 7e-15 55.2 0.0 9.1e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA35443.1 - 1.6e-12 47.7 0.1 4.3e-12 46.3 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA35443.1 - 1.9e-09 37.4 0.1 4.3e-06 26.4 0.1 2.5 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 KPA35443.1 - 0.0023 18.1 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KPA35443.1 - 0.0058 17.2 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 KPA35443.1 - 0.0095 15.4 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KPA35443.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Ank_2 PF12796.7 KPA35445.1 - 1.9e-27 95.6 2.5 1.8e-14 54.1 0.1 2.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA35445.1 - 1.3e-23 83.1 1.1 2.3e-09 37.6 0.2 4.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KPA35445.1 - 4.3e-15 55.4 4.2 0.0024 18.2 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KPA35445.1 - 5.1e-12 45.8 0.8 3.6e-06 27.1 0.2 4.3 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA35445.1 - 2.7e-11 42.6 0.4 0.19 12.4 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat EST1 PF10374.9 KPA35445.1 - 0.0039 17.8 0.1 0.0075 16.9 0.1 1.4 1 0 0 1 1 1 1 Telomerase activating protein Est1 NACHT PF05729.12 KPA35445.1 - 0.0045 16.9 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Peptidase_M10 PF00413.24 KPA35449.1 - 7.9e-07 29.1 0.2 1.5e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 KPA35449.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.6 KPA35449.1 - 0.00016 21.4 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KPA35449.1 - 0.0003 20.1 0.0 0.0005 19.4 0.0 1.4 1 0 0 1 1 1 1 Met-zincin Reprolysin_5 PF13688.6 KPA35449.1 - 0.0012 19.1 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KPA35449.1 - 0.0023 18.5 0.0 0.0038 17.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KPA35449.1 - 0.0032 17.4 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KPA35449.1 - 0.018 14.0 0.1 0.027 13.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.13 KPA35449.1 - 0.019 14.9 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Astacin PF01400.24 KPA35449.1 - 0.21 11.2 0.2 0.43 10.2 0.2 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) ERG4_ERG24 PF01222.17 KPA35450.1 - 1.6e-143 478.6 2.6 1.8e-143 478.4 2.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KPA35450.1 - 0.0054 16.3 0.2 0.0054 16.3 0.2 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) INCA1 PF15142.6 KPA35451.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 2 0 INCA1 MmgE_PrpD PF03972.14 KPA35452.1 - 2e-115 385.9 0.0 2.3e-115 385.7 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MFS_1 PF07690.16 KPA35453.1 - 3e-21 75.8 16.3 3.6e-21 75.5 16.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily CitMHS PF03600.16 KPA35454.1 - 5.3e-13 48.8 11.7 1.6e-12 47.2 11.7 1.9 1 1 0 1 1 1 1 Citrate transporter ArsB PF02040.15 KPA35454.1 - 1.6e-08 34.4 24.5 1e-05 25.1 10.9 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CAP PF00188.26 KPA35455.1 - 1.9e-08 35.2 0.3 3.2e-08 34.5 0.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MARVEL PF01284.23 KPA35456.1 - 0.0029 17.6 0.3 0.017 15.2 0.8 1.8 2 0 0 2 2 2 1 Membrane-associating domain DUF4231 PF14015.6 KPA35456.1 - 0.038 14.5 1.4 1.2 9.6 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Gemini_mov PF01708.16 KPA35456.1 - 0.26 11.1 3.6 4.1 7.2 1.8 2.7 2 1 0 3 3 3 0 Geminivirus putative movement protein Helitron_like_N PF14214.6 KPA35457.1 - 1.7e-41 142.5 2.7 3.1e-41 141.7 2.7 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KPA35457.1 - 4e-25 88.7 0.0 5.7e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KPA35457.1 - 3.1e-14 53.2 0.0 6.7e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPA35457.1 - 4.1e-10 40.2 0.0 7.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KPA35457.1 - 0.0031 16.7 0.0 0.0091 15.2 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AZUL PF16558.5 KPA35457.1 - 0.12 12.6 1.8 0.8 10.0 1.1 2.3 2 0 0 2 2 2 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A UPRTase PF14681.6 KPA35458.1 - 9.8e-36 123.1 0.7 2.5e-35 121.8 0.7 1.7 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.7 KPA35458.1 - 1.7e-19 70.9 0.1 2e-18 67.5 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 KPA35458.1 - 9.8e-17 61.7 0.0 2.8e-16 60.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA35458.1 - 0.00022 21.7 0.1 0.0012 19.3 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain PRTase_2 PF15609.6 KPA35458.1 - 0.00067 19.2 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase KAP_NTPase PF07693.14 KPA35458.1 - 0.0045 16.3 0.0 0.0077 15.5 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain Zeta_toxin PF06414.12 KPA35458.1 - 0.0066 15.7 0.8 0.071 12.4 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin Pribosyltran PF00156.27 KPA35458.1 - 0.0088 15.6 0.1 0.026 14.0 0.1 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain AAA_18 PF13238.6 KPA35458.1 - 0.016 15.8 0.0 0.039 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KPA35458.1 - 0.017 15.7 0.0 0.046 14.2 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KPA35458.1 - 0.018 15.3 0.0 0.059 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KPA35458.1 - 0.037 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Dimer_Tnp_hAT PF05699.14 KPA35459.1 - 1.1e-17 63.6 1.5 2.8e-17 62.3 1.5 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF5071 PF16804.5 KPA35459.1 - 0.018 15.3 0.1 0.055 13.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) zf-Sec23_Sec24 PF04810.15 KPA35459.1 - 0.093 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Exc PF07825.11 KPA35459.1 - 0.4 10.7 1.7 36 4.4 0.0 3.3 3 0 0 3 3 3 0 Excisionase-like protein FAD_binding_4 PF01565.23 KPA35460.1 - 4.2e-24 84.9 4.0 7.4e-24 84.1 4.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPA35460.1 - 5.1e-08 32.9 0.1 1.2e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like DNA_pol3_gamma3 PF12169.8 KPA35461.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III NACHT PF05729.12 KPA35462.1 - 2e-07 31.1 0.0 5.2e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 KPA35462.1 - 7.7e-07 28.7 0.0 2.1e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KPA35462.1 - 2.2e-05 24.7 0.3 0.0016 18.7 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KPA35462.1 - 9e-05 22.9 3.2 0.00015 22.2 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain PMEI PF04043.15 KPA35462.1 - 0.0017 18.7 1.7 0.48 10.7 0.1 2.9 3 0 0 3 3 3 2 Plant invertase/pectin methylesterase inhibitor Syntaxin_2 PF14523.6 KPA35462.1 - 0.13 12.7 0.5 0.56 10.6 0.1 2.3 2 0 0 2 2 2 0 Syntaxin-like protein RNase_T PF00929.24 KPA35463.1 - 0.00048 20.7 0.0 0.00067 20.2 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Ly49 PF08391.10 KPA35463.1 - 0.054 13.9 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region MIS13 PF08202.11 KPA35464.1 - 7.1e-57 193.0 0.0 1.4e-56 192.0 0.0 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family p450 PF00067.22 KPA35465.1 - 3.2e-33 115.2 0.0 4.3e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HTH_ABP1_N PF18107.1 KPA35465.1 - 0.052 13.3 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Cupin_7 PF12973.7 KPA35468.1 - 1.3e-07 31.4 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 KPA35468.1 - 0.0022 17.7 0.2 0.0057 16.4 0.2 1.6 1 1 1 2 2 2 1 Cupin domain AraC_binding PF02311.19 KPA35468.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain HET PF06985.11 KPA35470.1 - 1.2e-38 132.7 0.8 2.3e-38 131.9 0.8 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 KPA35470.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GMC_oxred_N PF00732.19 KPA35471.1 - 9.7e-49 166.3 0.0 1.3e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA35471.1 - 1.6e-29 103.3 0.0 2.8e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KPA35471.1 - 3.7e-05 23.5 0.4 9.3e-05 22.2 0.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPA35471.1 - 0.0013 18.0 1.3 0.076 12.1 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KPA35471.1 - 0.0023 18.1 0.5 0.0053 17.0 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPA35471.1 - 0.0092 15.2 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HHH PF00633.23 KPA35471.1 - 0.011 15.5 2.2 1.7 8.6 0.3 2.7 1 1 1 2 2 2 0 Helix-hairpin-helix motif Pyr_redox_3 PF13738.6 KPA35471.1 - 0.012 14.9 0.1 0.096 11.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA35471.1 - 0.029 13.6 0.1 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA35471.1 - 0.055 12.5 0.2 0.11 11.5 0.2 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KPA35471.1 - 0.06 12.6 1.2 0.66 9.2 0.3 2.5 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.14 KPA35471.1 - 0.14 10.8 0.1 0.98 8.0 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein F-box PF00646.33 KPA35472.1 - 0.0094 15.8 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KPA35472.1 - 0.011 15.7 0.0 0.036 14.0 0.0 1.9 2 0 0 2 2 2 0 F-box Methyltransf_12 PF08242.12 KPA35473.1 - 4.8e-11 43.3 0.0 3.8e-10 40.4 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA35473.1 - 5.1e-08 32.9 0.0 1.2e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA35473.1 - 1.3e-07 32.2 0.0 4.6e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA35473.1 - 2.2e-07 31.5 0.0 1.3e-06 29.0 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA35473.1 - 2.4e-06 27.4 0.0 6.5e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KPA35473.1 - 0.00035 20.3 0.0 0.0028 17.3 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 KPA35473.1 - 0.0074 15.6 0.3 0.025 13.9 0.0 2.0 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KPA35473.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_33 PF10017.9 KPA35473.1 - 0.016 14.3 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent NNMT_PNMT_TEMT PF01234.17 KPA35473.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family TPR_MLP1_2 PF07926.12 KPA35474.1 - 0.0098 16.0 12.6 0.086 12.9 3.4 3.1 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein ApoLp-III PF07464.11 KPA35474.1 - 0.017 15.2 15.7 0.99 9.5 1.3 4.3 4 2 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) KxDL PF10241.9 KPA35474.1 - 0.021 15.1 4.7 0.48 10.7 0.1 3.7 3 1 1 4 4 4 0 Uncharacterized conserved protein SRA1 PF07304.11 KPA35474.1 - 0.057 13.2 1.1 0.17 11.7 0.1 2.2 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) DUF745 PF05335.13 KPA35474.1 - 0.094 12.4 17.0 0.053 13.2 5.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF745) TPR_10 PF13374.6 KPA35474.1 - 0.15 12.0 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Goodbye PF17109.5 KPA35474.1 - 0.16 12.4 2.9 0.23 11.9 0.3 2.5 3 0 0 3 3 2 0 fungal STAND N-terminal Goodbye domain Fib_alpha PF08702.10 KPA35474.1 - 0.26 11.5 8.8 0.64 10.2 0.2 3.5 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family MbeD_MobD PF04899.12 KPA35474.1 - 0.32 11.1 2.6 0.86 9.8 1.0 2.6 2 1 1 3 3 2 0 MbeD/MobD like DUF1664 PF07889.12 KPA35474.1 - 0.32 11.0 11.2 10 6.2 0.1 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) YgaB PF14182.6 KPA35474.1 - 0.47 10.9 2.8 1.1 9.7 0.7 2.8 3 1 0 3 3 2 0 YgaB-like protein PIN_8 PF18476.1 KPA35474.1 - 1 9.1 9.0 0.88 9.4 0.9 2.8 2 1 0 2 2 2 0 PIN like domain DASH_Dad2 PF08654.10 KPA35474.1 - 1.1 9.7 4.4 13 6.2 0.2 2.9 2 1 0 2 2 2 0 DASH complex subunit Dad2 Prefoldin_2 PF01920.20 KPA35474.1 - 2.8 7.9 7.6 4.4 7.3 2.0 3.6 2 2 1 3 3 3 0 Prefoldin subunit GAS PF13851.6 KPA35474.1 - 4.1 6.7 9.8 5.2 6.4 3.2 3.2 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding CREPT PF16566.5 KPA35474.1 - 5.5 7.1 7.4 2.1 8.5 1.5 3.0 3 2 1 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour FAD_binding_3 PF01494.19 KPA35475.1 - 1.2e-18 67.5 2.7 3.3e-17 62.8 2.7 2.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA35475.1 - 4.3e-11 43.0 0.4 0.00024 20.8 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA35475.1 - 4.2e-07 29.5 0.7 6.3e-05 22.4 0.2 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA35475.1 - 2.8e-06 27.5 0.2 6.8e-06 26.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPA35475.1 - 5.7e-06 25.7 0.4 5.7e-06 25.7 0.4 2.3 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KPA35475.1 - 7.3e-05 21.6 0.2 0.001 17.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KPA35475.1 - 7.7e-05 23.2 0.2 0.00021 21.8 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA35475.1 - 9.6e-05 21.8 0.7 0.00082 18.7 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPA35475.1 - 0.00013 21.4 0.1 0.48 9.6 0.0 3.2 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KPA35475.1 - 0.013 14.9 0.7 0.023 14.0 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPA35475.1 - 0.014 15.3 0.9 0.087 12.8 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 KPA35475.1 - 0.03 13.4 0.8 0.051 12.7 0.8 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 KPA35475.1 - 0.039 13.6 0.1 0.21 11.2 0.0 2.3 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 KPA35475.1 - 0.045 13.0 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KPA35475.1 - 0.2 10.7 0.5 0.51 9.3 0.5 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein SE PF08491.10 KPA35475.1 - 0.23 10.4 0.0 1.6 7.7 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase TPP_enzyme_N PF02776.18 KPA35476.1 - 1.6e-38 132.0 0.1 2.9e-38 131.2 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KPA35476.1 - 7.6e-11 42.0 1.2 1.3e-10 41.3 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPA35476.1 - 2.6e-09 37.0 0.0 7.6e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Pyr_redox_3 PF13738.6 KPA35477.1 - 1.3e-11 44.3 0.0 1.6e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA35477.1 - 1.4e-11 44.2 0.0 2.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KPA35477.1 - 5.6e-06 25.1 0.0 7.7e-06 24.6 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPA35477.1 - 6.1e-06 25.7 0.0 1.4e-05 24.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 KPA35479.1 - 6.2e-07 29.9 0.8 0.001 19.6 0.4 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA35479.1 - 0.001 19.6 0.2 8.3 7.1 0.0 3.9 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Glyco_hydro_18 PF00704.28 KPA35480.1 - 9.7e-86 288.3 7.5 1.1e-85 288.1 7.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 KPA35481.1 - 8.6e-29 100.7 0.0 2.6e-28 99.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA35481.1 - 4.2e-13 49.2 0.0 5.9e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 KPA35482.1 - 1.3e-18 67.1 26.2 6.1e-18 64.9 26.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPA35482.1 - 0.012 14.9 10.0 1.7 7.9 0.0 2.6 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB DUF1634 PF07843.11 KPA35482.1 - 3.4 7.8 7.3 0.38 10.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) Amidohydro_1 PF01979.20 KPA35483.1 - 2.2e-40 139.1 0.0 3e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPA35483.1 - 7.9e-08 32.2 1.2 0.0023 17.5 0.1 2.8 2 1 0 2 2 2 2 Amidohydrolase family GFA PF04828.14 KPA35484.1 - 5.2e-22 78.0 0.3 8e-22 77.4 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KPA35484.1 - 0.019 15.1 1.5 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-P11 PF03854.14 KPA35484.1 - 0.023 14.4 0.8 0.036 13.7 0.0 1.7 2 0 0 2 2 2 0 P-11 zinc finger DDDD PF10161.9 KPA35486.1 - 0.028 14.2 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Acetyltransf_1 PF00583.25 KPA35487.1 - 1.5e-12 47.8 0.0 2.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA35487.1 - 3.1e-09 36.8 0.0 4.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA35487.1 - 7.1e-08 32.8 0.0 1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA35487.1 - 6.7e-06 26.0 0.2 2.5e-05 24.2 0.1 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KPA35487.1 - 0.00046 20.2 0.0 0.00074 19.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KPA35487.1 - 0.001 19.8 0.0 0.0014 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KPA35487.1 - 0.0016 18.6 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KPA35487.1 - 0.027 14.2 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Egh16-like PF11327.8 KPA35488.1 - 6.7e-54 183.1 5.9 6.7e-54 183.1 5.9 1.5 2 0 0 2 2 2 1 Egh16-like virulence factor p450 PF00067.22 KPA35489.1 - 1.2e-69 235.3 0.0 1.4e-69 235.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_125 PF06824.11 KPA35490.1 - 1.2e-15 57.3 0.1 2.5e-07 29.9 0.0 2.1 1 1 1 2 2 2 2 Metal-independent alpha-mannosidase (GH125) Transferase PF02458.15 KPA35491.1 - 7.3e-20 71.0 0.0 1.6e-19 69.9 0.0 1.4 1 1 0 1 1 1 1 Transferase family SnoaL_4 PF13577.6 KPA35492.1 - 1.3e-11 44.7 0.5 1.5e-11 44.5 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KPA35492.1 - 0.0025 18.2 0.6 0.0047 17.3 0.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Fungal_trans PF04082.18 KPA35493.1 - 3.5e-11 42.7 1.8 6e-11 41.9 1.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MAM PF00629.23 KPA35493.1 - 0.042 13.8 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu Oxidored_q6 PF01058.22 KPA35494.1 - 7.1e-22 77.6 0.0 1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Pkinase PF00069.25 KPA35496.1 - 7.5e-24 84.5 0.0 1.2e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA35496.1 - 1.4e-09 37.7 0.0 3.8e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPA35496.1 - 0.0018 17.7 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.26 KPA35496.1 - 0.021 15.2 0.1 0.048 14.0 0.1 1.6 1 0 0 1 1 1 0 FHA domain p450 PF00067.22 KPA35498.1 - 5.8e-12 45.1 0.0 1.5e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Kelch_4 PF13418.6 KPA35499.1 - 0.034 14.2 0.4 0.088 12.8 0.2 1.7 1 1 1 2 2 2 0 Galactose oxidase, central domain TMEM192 PF14802.6 KPA35499.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 TMEM192 family Acetyltransf_1 PF00583.25 KPA35500.1 - 9.9e-14 51.6 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA35500.1 - 2.6e-06 27.7 0.0 4.2e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA35500.1 - 3.2e-06 27.1 0.0 4.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA35500.1 - 6.4e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KPA35500.1 - 0.00028 21.0 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KPA35500.1 - 0.00031 21.4 0.0 0.00039 21.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF5456 PF17539.2 KPA35501.1 - 0.0033 17.3 0.3 0.0037 17.1 0.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5456) NB-ARC PF00931.22 KPA35502.1 - 1.6e-09 37.4 0.0 5.9e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KPA35502.1 - 0.00015 21.7 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 KPA35502.1 - 0.001 18.7 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KPA35502.1 - 0.0026 17.5 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Beta-lactamase PF00144.24 KPA35503.1 - 3.4e-13 49.6 0.0 4.5e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase L_lactis_ph-MCP PF06673.11 KPA35506.1 - 0.013 14.5 1.6 0.017 14.2 1.6 1.2 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein GrpE PF01025.19 KPA35506.1 - 0.045 13.4 1.6 0.061 13.0 1.6 1.2 1 0 0 1 1 1 0 GrpE zf-met PF12874.7 KPA35508.1 - 0.16 12.4 0.2 0.45 11.0 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Saccharop_dh_N PF04455.12 KPA35509.1 - 0.011 16.1 0.6 0.014 15.8 0.6 1.2 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region 30K_MP_C_Ter PF11330.8 KPA35509.1 - 0.016 14.6 4.4 0.017 14.5 4.4 1.0 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins DUF4878 PF12870.7 KPA35509.1 - 0.033 14.5 4.5 0.042 14.2 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) Atg14 PF10186.9 KPA35509.1 - 0.14 11.2 7.4 0.17 11.0 7.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sugar_tr PF00083.24 KPA35510.1 - 1.9e-102 343.4 22.4 2.2e-102 343.3 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA35510.1 - 1.4e-23 83.4 38.3 1.5e-17 63.6 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WHIM1 PF15612.6 KPA35511.1 - 0.017 14.6 0.0 0.06 12.9 0.0 1.9 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 PI-PLC-X PF00388.19 KPA35512.1 - 2.6e-56 189.2 0.0 4.7e-56 188.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain TRP PF06011.12 KPA35512.1 - 2.3e-11 43.1 19.7 8.6e-07 28.0 8.5 3.2 2 2 0 2 2 2 2 Transient receptor potential (TRP) ion channel Abhydrolase_6 PF12697.7 KPA35513.1 - 1.7e-20 74.6 0.0 3.1e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA35513.1 - 3.5e-20 72.3 0.0 2.1e-19 69.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA35513.1 - 1.8e-14 54.0 0.1 2.1e-11 44.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KPA35513.1 - 1e-05 25.2 0.0 0.096 12.2 0.0 2.5 2 1 0 2 2 2 2 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KPA35513.1 - 1.8e-05 23.8 0.0 2.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KPA35513.1 - 0.00044 20.1 0.2 0.89 9.3 0.0 2.6 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KPA35513.1 - 0.00063 19.3 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family PAF-AH_p_II PF03403.13 KPA35513.1 - 0.00098 17.7 0.2 0.0065 15.0 0.2 1.9 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.11 KPA35513.1 - 0.03 13.3 0.1 0.047 12.7 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase Fungal_trans PF04082.18 KPA35513.1 - 0.037 13.1 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Abhydrolase_5 PF12695.7 KPA35513.1 - 0.11 12.3 0.1 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KPA35513.1 - 0.17 11.6 0.2 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein Spidroin_N PF16763.5 KPA35514.1 - 0.13 12.3 0.1 0.2 11.7 0.1 1.2 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term 2-Hacid_dh_C PF02826.19 KPA35515.1 - 9.8e-23 80.4 0.1 6.6e-15 54.9 0.1 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPA35515.1 - 2e-09 37.2 0.0 2.4e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AOC_like PF18678.1 KPA35515.1 - 0.018 14.7 0.2 0.034 13.8 0.2 1.4 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain Sacchrp_dh_NADP PF03435.18 KPA35515.1 - 0.033 14.4 0.1 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain SAP PF02037.27 KPA35515.1 - 0.071 12.9 1.1 11 5.8 0.0 3.1 3 0 0 3 3 3 0 SAP domain GEN1_C PF18380.1 KPA35518.1 - 4.9e-14 53.1 0.1 1.8e-13 51.3 0.1 2.0 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 KPA35518.1 - 9.9e-07 29.2 0.0 4e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain Mononeg_RNA_pol PF00946.19 KPA35518.1 - 0.1 10.2 0.0 0.15 9.7 0.0 1.1 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase MgsA_C PF12002.8 KPA35519.1 - 1.1e-51 175.1 0.0 1.2e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal Fungal_trans_2 PF11951.8 KPA35520.1 - 0.0007 18.5 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.21 KPA35522.1 - 2.1e-12 47.0 0.2 1.1e-05 25.0 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPA35522.1 - 1.2e-08 35.0 1.0 1.1e-07 32.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KPA35522.1 - 1.4e-07 32.0 0.1 2.8e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KPA35522.1 - 1.2e-05 25.0 0.7 2.3e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KPA35522.1 - 0.00016 21.2 0.1 0.022 14.2 0.1 2.2 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KPA35522.1 - 0.00026 20.2 0.0 0.00075 18.7 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KPA35522.1 - 0.00027 20.0 0.0 0.0038 16.3 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KPA35522.1 - 0.0028 16.8 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DHDPS PF00701.22 KPA35523.1 - 4.2e-61 206.2 0.0 4.7e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FRQ PF09421.10 KPA35524.1 - 3.5e-236 786.7 16.9 4.3e-236 786.4 16.9 1.0 1 0 0 1 1 1 1 Frequency clock protein DUF5350 PF17299.2 KPA35524.1 - 0.71 10.4 3.2 0.32 11.5 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5350) Hydrolase_4 PF12146.8 KPA35525.1 - 2.5e-10 40.0 0.1 1.6e-09 37.4 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA35525.1 - 1.9e-09 38.5 0.2 2.4e-09 38.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 KPA35525.1 - 1e-07 31.0 0.1 0.00038 19.2 0.0 2.9 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KPA35525.1 - 0.00033 20.2 0.1 0.052 13.0 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 KPA35525.1 - 0.0032 17.4 0.1 0.033 14.1 0.1 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Pyr_redox_2 PF07992.14 KPA35526.1 - 2.2e-09 37.0 0.0 0.15 11.3 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA35526.1 - 1.9e-06 28.0 0.3 0.0011 19.0 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPA35526.1 - 0.00012 22.2 0.0 0.00038 20.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KPA35526.1 - 0.00042 18.9 0.0 0.0041 15.6 0.0 2.1 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPA35526.1 - 0.0021 17.3 0.0 2 7.5 0.0 3.5 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPA35526.1 - 0.029 13.6 0.0 2 7.6 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA35526.1 - 0.18 11.4 0.0 1.9 8.0 0.0 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase DUF2229 PF09989.9 KPA35529.1 - 0.017 14.8 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) MFS_1 PF07690.16 KPA35531.1 - 4.1e-25 88.5 23.1 4.6e-25 88.3 23.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M19 PF01244.21 KPA35532.1 - 1.1e-101 340.2 0.0 1.2e-101 340.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Hemopexin PF00045.19 KPA35532.1 - 0.05 13.6 1.8 0.11 12.4 1.8 1.6 1 0 0 1 1 1 0 Hemopexin LZ_Tnp_IS66 PF13007.7 KPA35533.1 - 1.6 9.6 6.3 0.58 11.0 1.4 2.3 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Acetyltransf_3 PF13302.7 KPA35534.1 - 4.3e-13 50.1 0.1 7.2e-13 49.4 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA35534.1 - 0.0011 19.2 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA35534.1 - 0.026 14.9 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hemerythrin PF01814.23 KPA35535.1 - 1.4e-10 41.9 3.1 2e-10 41.4 3.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Glyco_hydro_76 PF03663.14 KPA35536.1 - 3.6e-155 517.0 16.1 4.5e-155 516.7 16.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KPA35536.1 - 0.0011 18.2 1.0 0.0011 18.2 1.0 3.2 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 Glyco_hydro_3_C PF01915.22 KPA35537.1 - 1.1e-45 156.1 0.0 2.4e-45 155.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPA35537.1 - 2.3e-43 148.8 0.0 3.6e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPA35537.1 - 2.1e-22 79.0 0.1 4e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain HNH_2 PF13391.6 KPA35538.1 - 2.5e-08 33.9 0.2 6e-08 32.7 0.2 1.7 1 0 0 1 1 1 1 HNH endonuclease HgmA PF04209.13 KPA35540.1 - 7.7e-126 420.2 0.0 9.4e-126 419.9 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase IPK PF03770.16 KPA35541.1 - 1.3e-56 191.7 0.0 1.9e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase GST_N_3 PF13417.6 KPA35542.1 - 7.9e-10 39.0 0.1 2.6e-09 37.4 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPA35542.1 - 2.4e-09 37.3 0.0 4.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPA35542.1 - 8.6e-06 25.7 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA35542.1 - 0.021 15.0 0.0 0.044 14.0 0.0 1.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA35542.1 - 0.054 13.7 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Acetyltransf_CG PF14542.6 KPA35543.1 - 0.0002 21.4 0.1 0.00047 20.2 0.0 1.6 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 KPA35543.1 - 0.0068 16.4 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA35543.1 - 0.0078 16.3 0.0 0.066 13.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA35543.1 - 0.021 15.0 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TbpB_A PF17484.2 KPA35543.1 - 0.061 14.1 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 N-Lobe handle Tf-binding protein B Phage_integrase PF00589.22 KPA35543.1 - 0.093 12.5 0.1 4.4 7.1 0.0 2.2 1 1 1 2 2 2 0 Phage integrase family FlaC_arch PF05377.11 KPA35545.1 - 0.018 15.4 0.4 0.043 14.2 0.2 1.7 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Glyco_hydro_16 PF00722.21 KPA35546.1 - 4.4e-14 52.3 0.1 6.9e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KPA35546.1 - 0.044 12.2 0.6 2.1 6.7 0.5 2.1 2 0 0 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) DUF5484 PF17583.2 KPA35546.1 - 0.24 11.1 2.1 0.5 10.1 1.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5484) B_lectin PF01453.24 KPA35547.1 - 1.7e-11 44.6 0.0 2e-07 31.5 0.0 2.0 1 1 1 2 2 2 2 D-mannose binding lectin BofC_C PF08955.10 KPA35547.1 - 0.002 18.1 0.0 0.11 12.6 0.0 2.8 3 0 0 3 3 3 1 BofC C-terminal domain DEAD PF00270.29 KPA35548.1 - 2.4e-08 33.9 0.2 9.1e-08 32.1 0.2 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KPA35548.1 - 1e-05 25.6 0.0 2.9e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit OrsD PF12013.8 KPA35548.1 - 0.0046 17.4 3.0 0.014 15.9 3.0 1.9 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D TauD PF02668.16 KPA35549.1 - 8.8e-09 35.5 0.0 1.1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FemAB PF02388.16 KPA35549.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 FemAB family Glyco_hydro_32N PF00251.20 KPA35550.1 - 1.3e-71 241.6 6.0 1.6e-71 241.4 6.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KPA35550.1 - 3.2e-20 72.7 0.2 5.6e-20 71.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BTB PF00651.31 KPA35551.1 - 2.6e-21 75.9 0.2 4e-21 75.3 0.2 1.2 1 0 0 1 1 1 1 BTB/POZ domain zf_UBZ PF18439.1 KPA35551.1 - 0.013 15.1 1.2 0.26 10.9 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KPA35551.1 - 0.032 14.2 1.5 1.1 9.3 1.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KPA35551.1 - 0.1 12.7 2.1 0.27 11.4 2.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KPA35551.1 - 0.15 11.6 1.9 0.35 10.4 1.9 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding IBR PF01485.21 KPA35551.1 - 0.22 11.7 1.5 0.48 10.7 1.5 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Auto_anti-p27 PF06677.12 KPA35551.1 - 0.26 11.5 1.5 1.3 9.3 1.2 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-TFIIB PF13453.6 KPA35551.1 - 0.36 10.2 5.0 3.2 7.2 0.3 2.5 1 1 1 2 2 2 0 Transcription factor zinc-finger Jiv90 PF14901.6 KPA35551.1 - 0.37 11.0 2.7 0.88 9.8 0.2 2.4 2 1 0 2 2 2 0 Cleavage inducing molecular chaperone Zn_Tnp_IS91 PF14319.6 KPA35551.1 - 0.48 10.5 3.5 0.88 9.6 1.4 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-C2H2_4 PF13894.6 KPA35551.1 - 2 9.4 10.6 6.1 8.0 1.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KPA35551.1 - 2.2 8.3 5.8 10 6.2 0.1 2.6 2 1 0 3 3 3 0 SprT-like zinc ribbon domain zinc_ribbon_9 PF14369.6 KPA35551.1 - 3.4 8.0 5.2 17 5.8 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon HET PF06985.11 KPA35552.1 - 1.2e-24 87.3 0.0 1.9e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LysM PF01476.20 KPA35554.1 - 3e-22 78.4 0.4 9.6e-05 22.4 0.0 5.5 5 0 0 5 5 5 5 LysM domain Glyco_transf_90 PF05686.12 KPA35555.1 - 4.7e-09 35.7 0.2 5.5e-06 25.5 0.1 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 Zn_clus PF00172.18 KPA35556.1 - 1.2e-08 34.9 12.3 2e-08 34.2 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IU_nuc_hydro PF01156.19 KPA35560.1 - 0.00034 20.3 0.0 0.00095 18.8 0.0 1.7 1 1 1 2 2 2 1 Inosine-uridine preferring nucleoside hydrolase bZIP_1 PF00170.21 KPA35561.1 - 2.3e-07 30.8 6.7 2.3e-07 30.8 6.7 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KPA35561.1 - 0.015 15.4 9.5 0.059 13.5 9.5 2.1 1 1 0 1 1 1 0 Basic region leucine zipper 2-Hacid_dh_C PF02826.19 KPA35562.1 - 6e-47 159.3 0.0 9.2e-47 158.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPA35562.1 - 0.00026 20.7 0.0 0.003 17.2 0.0 2.0 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KPA35562.1 - 0.013 15.6 0.0 0.049 13.7 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 KPA35562.1 - 0.018 15.5 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 KPA35562.1 - 0.06 13.1 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.20 KPA35562.1 - 0.093 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Esterase PF00756.20 KPA35563.1 - 1.2e-08 35.0 0.0 6e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KPA35563.1 - 1.5e-05 24.4 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPA35563.1 - 0.0043 16.6 0.0 0.009 15.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KPA35563.1 - 0.0097 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA35563.1 - 0.012 16.2 0.0 0.014 16.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KPA35563.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Toxin_30 PF08117.11 KPA35564.1 - 0.00017 21.8 1.3 0.00053 20.2 1.3 1.8 1 0 0 1 1 1 1 Ptu family FA_FANCE PF11510.8 KPA35565.1 - 0.12 11.7 0.3 0.18 11.2 0.3 1.2 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE TAD2 PF18521.1 KPA35565.1 - 8.9 6.5 7.3 1.1e+02 3.0 3.2 3.4 3 0 0 3 3 3 0 Transactivation domain 2 Abhydrolase_6 PF12697.7 KPA35566.1 - 2.8e-09 37.9 0.0 3.3e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA35566.1 - 6.2e-07 28.9 0.0 8.4e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA35566.1 - 2e-05 24.4 0.0 2.9e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold NPCC PF08058.11 KPA35569.1 - 0.011 15.7 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore complex component Form_Nir_trans PF01226.17 KPA35571.1 - 3.6e-72 242.5 17.8 4.1e-72 242.3 17.8 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Ceramidase PF05875.12 KPA35572.1 - 2e-54 184.8 5.5 2.4e-54 184.5 5.5 1.0 1 0 0 1 1 1 1 Ceramidase S1FA PF04689.13 KPA35572.1 - 0.02 15.0 0.1 0.039 14.1 0.1 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA Leader_Trp PF08255.11 KPA35572.1 - 0.13 12.3 1.4 0.35 10.9 1.4 1.8 1 0 0 1 1 1 0 Trp-operon Leader Peptide CcmD PF04995.14 KPA35573.1 - 7 6.8 5.4 11 6.2 5.4 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Mpv17_PMP22 PF04117.12 KPA35574.1 - 2.4e-18 66.1 0.2 4.8e-18 65.1 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2530 PF10745.9 KPA35574.1 - 0.034 14.4 0.7 0.034 14.4 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) ET PF01684.16 KPA35575.1 - 0.045 14.1 3.5 0.14 12.5 0.1 2.5 2 0 0 2 2 2 0 ET module GW PF13457.6 KPA35576.1 - 0.048 14.3 0.4 0.14 12.8 0.0 2.0 2 0 0 2 2 2 0 GW (Gly-Tryp) dipeptide domain Aminotran_1_2 PF00155.21 KPA35577.1 - 4.1e-68 230.2 0.0 4.7e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF296 PF03479.15 KPA35577.1 - 0.057 13.8 0.3 0.12 12.8 0.3 1.4 1 0 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain AA_permease PF00324.21 KPA35578.1 - 5e-67 226.5 12.6 5.5e-67 226.4 12.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA35578.1 - 3e-18 65.9 12.6 4e-18 65.5 12.6 1.1 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.17 KPA35578.1 - 0.0022 17.4 4.1 0.0023 17.3 3.1 1.4 1 1 0 1 1 1 1 Sodium:alanine symporter family Chromo PF00385.24 KPA35579.1 - 4.3e-08 32.9 6.0 0.00011 22.1 0.5 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Intein_splicing PF14890.6 KPA35579.1 - 0.0019 18.1 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Intein splicing domain Tudor-knot PF11717.8 KPA35579.1 - 0.012 15.5 0.5 0.021 14.7 0.5 1.4 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain MFS_1 PF07690.16 KPA35580.1 - 2.1e-46 158.5 40.0 4.8e-46 157.3 40.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA35580.1 - 4.6e-12 45.6 7.1 4.6e-12 45.6 7.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPA35580.1 - 2.1e-07 29.8 22.5 2.8e-07 29.3 22.5 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KPA35580.1 - 5.9e-05 22.5 5.2 5.9e-05 22.5 5.2 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB YjcB PF15940.5 KPA35580.1 - 0.46 10.7 4.3 0.4 10.9 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function OATP PF03137.20 KPA35580.1 - 3.5 5.8 14.9 0.032 12.5 0.9 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Trp_oprn_chp PF09534.10 KPA35580.1 - 7.3 6.3 8.2 0.38 10.5 1.4 2.3 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PIF1 PF05970.14 KPA35582.1 - 5.8e-33 114.5 0.0 2.5e-22 79.5 0.0 2.6 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 KPA35582.1 - 1.6e-20 73.6 0.2 2.7e-17 63.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KPA35582.1 - 2.6e-11 44.1 0.0 4.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KPA35582.1 - 6.2e-05 23.0 0.2 0.0037 17.2 0.1 2.3 1 1 1 2 2 2 1 NTPase AAA_22 PF13401.6 KPA35582.1 - 7.2e-05 23.1 0.1 0.00034 20.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 KPA35582.1 - 7.8e-05 21.8 0.3 0.00012 21.2 0.3 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KPA35582.1 - 0.00097 18.9 0.1 0.0034 17.1 0.1 1.9 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KPA35582.1 - 0.001 19.1 0.0 0.0042 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPA35582.1 - 0.0022 18.4 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KPA35582.1 - 0.0038 17.7 0.0 0.0067 16.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KPA35582.1 - 0.0073 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 KPA35582.1 - 0.0074 15.2 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 KPA35582.1 - 0.0078 16.7 0.0 0.021 15.3 0.0 1.7 2 0 0 2 2 1 1 ABC transporter AAA_29 PF13555.6 KPA35582.1 - 0.0096 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.6 KPA35582.1 - 0.011 15.7 0.0 0.063 13.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KPA35582.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_10 PF12846.7 KPA35582.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.12 KPA35582.1 - 0.019 14.3 0.4 0.046 13.0 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KPA35582.1 - 0.022 14.7 0.0 0.07 13.0 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Helicase_RecD PF05127.14 KPA35582.1 - 0.026 14.4 0.5 0.082 12.8 0.5 1.7 1 1 0 1 1 1 0 Helicase MobB PF03205.14 KPA35582.1 - 0.03 14.2 0.1 0.15 12.0 0.0 2.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KPA35582.1 - 0.05 14.2 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KPA35582.1 - 0.059 12.9 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KPA35582.1 - 0.079 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KPA35582.1 - 0.092 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KPA35582.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase RNA_helicase PF00910.22 KPA35582.1 - 0.16 12.3 0.0 0.76 10.2 0.0 2.0 1 1 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KPA35582.1 - 0.17 11.0 0.1 0.41 9.8 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain DEAD PF00270.29 KPA35582.1 - 0.18 11.6 0.2 15 5.3 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase T2SSE PF00437.20 KPA35582.1 - 0.19 10.8 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 KPA35582.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain RdRP PF05183.12 KPA35583.1 - 3.2e-74 250.6 0.0 4.4e-73 246.9 0.0 2.1 1 1 0 1 1 1 1 RNA dependent RNA polymerase Endonuclease_1 PF04231.13 KPA35585.1 - 0.025 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Endonuclease I F-box-like PF12937.7 KPA35586.1 - 0.0089 15.9 0.0 0.042 13.8 0.0 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KPA35586.1 - 3.6 8.1 14.1 28 5.3 0.0 6.6 6 2 1 7 7 7 0 Leucine Rich repeats (2 copies) DUF3632 PF12311.8 KPA35587.1 - 1.1e-30 107.4 0.0 1.6e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Antifungal_prot PF11402.8 KPA35588.1 - 1.5e-21 76.4 13.0 1.8e-21 76.1 13.0 1.1 1 0 0 1 1 1 1 Antifungal protein CN_hydrolase PF00795.22 KPA35590.1 - 3.1e-13 49.6 0.0 1.4e-11 44.3 0.0 2.6 3 0 0 3 3 3 2 Carbon-nitrogen hydrolase RRM_1 PF00076.22 KPA35591.1 - 7.7e-25 86.5 0.0 9.1e-25 86.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPA35591.1 - 1.5e-05 25.0 0.0 2.5e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 KPA35591.1 - 0.035 14.2 0.1 0.062 13.4 0.1 1.4 1 1 0 1 1 1 0 Limkain b1 GRP PF07172.11 KPA35591.1 - 0.053 14.2 13.5 0.064 13.9 13.5 1.3 1 0 0 1 1 1 0 Glycine rich protein family ADH_zinc_N PF00107.26 KPA35593.1 - 1.6e-10 41.1 0.0 5.7e-10 39.3 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA35593.1 - 0.0086 15.9 0.0 0.022 14.7 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPA35593.1 - 0.02 15.9 0.0 0.035 15.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPA35593.1 - 0.027 14.4 0.0 0.093 12.6 0.0 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase AMP-binding PF00501.28 KPA35595.1 - 2e-18 66.2 0.0 2.3e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme TctC PF03401.14 KPA35595.1 - 0.094 11.8 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor Methyltransf_23 PF13489.6 KPA35596.1 - 1.8e-17 63.7 0.0 3.6e-17 62.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA35596.1 - 1.2e-11 45.2 0.0 3e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA35596.1 - 1.4e-10 41.7 0.0 2.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA35596.1 - 1.2e-07 32.4 0.0 5.7e-07 30.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA35596.1 - 4e-06 26.7 0.0 6.2e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA35596.1 - 4.4e-05 22.9 0.0 0.0002 20.8 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPA35596.1 - 0.0054 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KPA35596.1 - 0.013 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KPA35596.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KPA35596.1 - 0.028 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 KPA35596.1 - 0.045 13.1 0.0 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) F-box-like PF12937.7 KPA35597.1 - 3.1e-05 23.8 0.4 0.00028 20.7 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KPA35597.1 - 0.017 15.0 0.6 0.045 13.7 0.1 2.0 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 KPA35597.1 - 0.021 14.7 0.2 0.053 13.4 0.2 1.7 1 0 0 1 1 1 0 F-box RSN1_TM PF13967.6 KPA35601.1 - 2.5e-40 137.8 1.2 2.5e-40 137.8 1.2 1.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KPA35601.1 - 3.6e-20 72.9 0.0 5.6e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 KPA35601.1 - 1.4e-11 44.2 3.4 1.4e-11 44.2 3.4 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate ThiC_Rad_SAM PF01964.18 KPA35601.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Radical SAM ThiC family Zn_clus PF00172.18 KPA35604.1 - 9e-10 38.5 11.2 1.2e-09 38.1 11.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BUD22 PF09073.10 KPA35606.1 - 0.016 14.6 8.4 0.023 14.1 8.4 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 KPA35606.1 - 4.6 5.2 6.7 6.1 4.8 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-binding PF00249.31 KPA35607.1 - 1.5e-37 127.6 1.1 3.9e-12 46.2 0.0 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPA35607.1 - 5.5e-32 109.8 0.1 9.9e-11 41.7 0.0 4.2 3 2 2 5 5 5 3 Myb-like DNA-binding domain Rap1_C PF11626.8 KPA35607.1 - 0.039 14.0 0.0 29 4.8 0.0 3.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3792 PF12670.7 KPA35609.1 - 0.038 14.2 0.3 0.053 13.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) DUF202 PF02656.15 KPA35610.1 - 0.26 11.7 4.6 0.11 12.9 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) THF_DHG_CYH PF00763.23 KPA35611.1 - 2.9e-20 72.7 0.0 4.3e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KPA35611.1 - 1.5e-08 34.1 0.0 5.5e-08 32.3 0.0 1.9 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PUNUT PF16913.5 KPA35611.1 - 0.087 12.0 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport Dimer_Tnp_hAT PF05699.14 KPA35613.1 - 4.4e-22 77.7 0.6 1.1e-21 76.4 0.6 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Rpn3_C PF08375.11 KPA35613.1 - 0.21 12.1 0.6 0.49 10.8 0.6 1.6 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal IBR PF01485.21 KPA35617.1 - 1.1e-11 44.7 44.2 5.8e-08 32.8 4.1 4.6 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_14 PF17978.1 KPA35617.1 - 0.037 14.5 0.6 0.037 14.5 0.6 3.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF5398 PF17376.2 KPA35617.1 - 0.15 12.7 0.3 0.32 11.6 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5398) Bul1_C PF04426.12 KPA35618.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Bul1 C terminus p450 PF00067.22 KPA35619.1 - 3.5e-57 194.2 0.0 5.4e-57 193.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 CCDC168_N PF15804.5 KPA35621.1 - 0.044 13.6 0.2 0.066 13.0 0.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 168 Ank_2 PF12796.7 KPA35622.1 - 2.4e-46 156.2 0.0 2.2e-16 60.2 0.1 4.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) SesA PF17107.5 KPA35622.1 - 1.3e-33 115.7 1.0 4.8e-33 113.9 0.1 2.5 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_4 PF13637.6 KPA35622.1 - 5.5e-26 90.6 1.6 8.2e-10 39.0 0.0 5.8 3 2 4 7 7 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA35622.1 - 3.4e-21 75.0 0.1 2.3e-06 27.8 0.1 7.0 5 1 3 8 8 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KPA35622.1 - 3.7e-21 74.6 1.2 1.7e-05 25.0 0.0 7.7 8 0 0 8 8 8 3 Ankyrin repeat Ank_3 PF13606.6 KPA35622.1 - 1.2e-19 68.3 0.1 0.00013 22.1 0.0 7.3 7 0 0 7 7 6 5 Ankyrin repeat NACHT PF05729.12 KPA35622.1 - 1e-05 25.6 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPA35622.1 - 0.00014 22.3 2.7 0.00035 21.0 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KPA35622.1 - 0.0097 16.2 0.1 0.065 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Spore_III_AB PF09548.10 KPA35622.1 - 0.01 16.0 3.5 0.49 10.5 0.5 2.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) AAA_25 PF13481.6 KPA35622.1 - 0.027 14.0 0.2 4.9 6.7 0.0 3.0 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 KPA35622.1 - 0.062 13.7 0.0 0.37 11.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase His_Phos_2 PF00328.22 KPA35622.1 - 0.079 12.3 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DUF2795 PF11387.8 KPA35622.1 - 0.71 10.1 2.3 1.1 9.6 0.1 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF2795) HNH_2 PF13391.6 KPA35624.1 - 9.1e-13 48.2 0.3 2.4e-12 46.8 0.3 1.8 1 0 0 1 1 1 1 HNH endonuclease DDE_1 PF03184.19 KPA35625.1 - 5.3e-12 45.7 0.1 6.6e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KPA35625.1 - 4.1e-08 33.1 2.6 1e-07 31.9 2.6 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KPA35625.1 - 0.0021 17.8 0.0 0.0088 15.8 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease BPL_N PF09825.9 KPA35626.1 - 1.7e-08 34.0 0.4 4.3e-05 22.8 0.3 2.2 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal ChitinaseA_N PF08329.10 KPA35626.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Tannase PF07519.11 KPA35627.1 - 3.5e-88 296.6 0.1 4.3e-88 296.3 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KPA35627.1 - 3.8e-06 26.5 0.1 0.0086 15.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2457 PF10446.9 KPA35629.1 - 0.25 10.4 0.3 0.54 9.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF2310 PF10071.9 KPA35630.1 - 0.06 12.6 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) RRM_1 PF00076.22 KPA35631.1 - 1.1e-25 89.3 0.0 1.3e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPA35631.1 - 0.00067 19.7 0.0 0.0012 18.9 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KPA35631.1 - 0.014 14.9 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4944 PF16302.5 KPA35631.1 - 0.043 13.9 0.1 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4944) Nup35_RRM_2 PF14605.6 KPA35631.1 - 0.069 13.2 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KPA35631.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KPA35631.1 - 0.17 12.1 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Calcipressin PF04847.12 KPA35631.1 - 0.19 11.5 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Calcipressin GRP PF07172.11 KPA35631.1 - 1.1 9.9 22.6 1.5 9.5 22.6 1.3 1 0 0 1 1 1 0 Glycine rich protein family OrsD PF12013.8 KPA35634.1 - 1.9e-11 44.4 2.4 1.9e-11 44.4 2.4 1.7 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_12 PF18658.1 KPA35634.1 - 0.072 12.7 0.0 0.072 12.7 0.0 2.3 2 1 0 2 2 2 0 Zinc-finger C2H2-type Glycohydro_20b2 PF14845.6 KPA35635.1 - 0.11 13.2 6.4 0.12 13.0 0.0 2.7 2 1 0 2 2 2 0 beta-acetyl hexosaminidase like HBD PF18534.1 KPA35635.1 - 0.16 12.1 0.8 0.34 11.1 0.8 1.5 1 0 0 1 1 1 0 Helical bundle domain Peptidase_M16 PF00675.20 KPA35635.1 - 0.33 10.9 1.6 2.6 8.0 0.6 2.4 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) DUF948 PF06103.11 KPA35635.1 - 2.3 8.5 5.9 19 5.6 0.3 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Mannosyl_trans3 PF11051.8 KPA35636.1 - 2.3e-51 174.8 0.0 1.9e-31 109.5 0.0 2.3 1 1 1 2 2 2 2 Mannosyltransferase putative Ribonuclease_T2 PF00445.18 KPA35637.1 - 9.4e-45 153.1 1.4 1.3e-44 152.6 1.4 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family SBDS_C PF09377.10 KPA35637.1 - 0.051 13.6 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 SBDS protein C-terminal domain MFS_1 PF07690.16 KPA35639.1 - 5.4e-11 42.0 23.4 2.6e-10 39.8 23.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily AA_permease PF00324.21 KPA35642.1 - 3.5e-116 388.6 36.8 4.5e-116 388.3 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA35642.1 - 2.7e-31 108.9 40.8 3.4e-31 108.5 40.8 1.2 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.17 KPA35642.1 - 0.17 11.2 16.9 0.023 14.0 9.3 2.4 2 1 0 2 2 2 0 Sodium:alanine symporter family HpcH_HpaI PF03328.14 KPA35643.1 - 3.5e-30 104.8 0.0 5.1e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 KPA35643.1 - 0.0084 15.2 0.9 0.18 10.9 0.4 2.6 2 1 0 2 2 2 1 PEP-utilising enzyme, TIM barrel domain PK PF00224.21 KPA35643.1 - 0.04 12.8 0.1 0.058 12.3 0.1 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain 4HFCP_synth PF04476.13 KPA35643.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 4-HFC-P synthase MFS_1 PF07690.16 KPA35644.1 - 3.4e-33 115.0 23.0 3.4e-33 115.0 23.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA35644.1 - 7.6e-15 54.7 8.1 7.6e-15 54.7 8.1 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KPA35644.1 - 2.6e-06 26.2 4.2 5.2e-06 25.2 4.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3169 PF11368.8 KPA35644.1 - 0.097 12.2 12.7 0.56 9.7 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3169) HNH_2 PF13391.6 KPA35648.1 - 0.0024 18.0 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease FTA2 PF13095.6 KPA35649.1 - 1.5e-43 148.9 0.0 6.9e-23 81.4 0.0 2.0 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KPA35649.1 - 0.025 13.9 0.0 0.66 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Fungal_trans PF04082.18 KPA35650.1 - 5.1e-19 68.3 0.0 9.9e-19 67.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA35650.1 - 1.4e-08 34.7 7.7 2.9e-08 33.7 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_35 PF14516.6 KPA35650.1 - 0.15 10.9 0.0 0.31 9.8 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain zf-H2C2_2 PF13465.6 KPA35651.1 - 0.022 15.2 0.6 0.022 15.2 0.6 4.3 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2 PF00096.26 KPA35651.1 - 0.027 14.9 0.8 0.027 14.9 0.8 4.9 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-CHCC PF10276.9 KPA35651.1 - 0.053 13.6 3.0 4.4 7.4 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger domain DUF2318 PF10080.9 KPA35651.1 - 0.12 12.5 0.5 0.61 10.2 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) HypA PF01155.19 KPA35651.1 - 0.52 10.3 2.2 0.98 9.5 2.2 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_recom PF13408.6 KPA35651.1 - 0.59 10.7 5.1 11 6.6 0.6 2.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C2H2_4 PF13894.6 KPA35651.1 - 3.8 8.6 29.4 0.12 13.3 1.4 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger MFS_1 PF07690.16 KPA35652.1 - 2e-34 119.1 29.1 2.8e-34 118.6 29.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4381 PF14316.6 KPA35652.1 - 0.16 12.2 0.3 6.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) UL42 PF17638.2 KPA35652.1 - 0.19 11.7 0.4 0.51 10.3 0.4 1.7 1 0 0 1 1 1 0 HCMV UL42 TauD PF02668.16 KPA35653.1 - 1.5e-57 195.4 0.5 1.9e-57 195.1 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_4 PF01565.23 KPA35655.1 - 6.1e-22 77.9 1.6 6.1e-22 77.9 1.6 1.5 2 0 0 2 2 2 1 FAD binding domain YojJ PF10372.9 KPA35656.1 - 0.00061 19.8 0.2 0.03 14.4 0.1 2.9 1 1 1 2 2 2 1 Bacterial membrane-spanning protein N-terminus Golgin_A5 PF09787.9 KPA35656.1 - 0.0097 15.4 4.2 0.0097 15.4 4.2 2.3 2 0 0 2 2 2 1 Golgin subfamily A member 5 Hemagglutinin PF00509.18 KPA35656.1 - 0.012 14.1 0.2 0.017 13.6 0.2 1.2 1 0 0 1 1 1 0 Haemagglutinin FlaC_arch PF05377.11 KPA35656.1 - 0.017 15.5 0.5 2.6 8.5 0.1 2.8 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) LXG PF04740.12 KPA35656.1 - 0.032 13.9 2.0 0.36 10.5 0.3 2.4 1 1 0 1 1 1 0 LXG domain of WXG superfamily DUF677 PF05055.12 KPA35656.1 - 0.045 12.6 0.6 0.07 12.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) KxDL PF10241.9 KPA35656.1 - 0.065 13.5 2.4 0.52 10.6 0.3 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 KPA35656.1 - 0.071 13.1 7.4 2 8.5 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KPA35656.1 - 0.13 12.3 1.5 2 8.5 0.2 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-SNARE PF05008.15 KPA35656.1 - 0.13 12.7 10.2 1.3 9.4 0.0 3.8 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Occludin_ELL PF07303.13 KPA35656.1 - 0.2 12.4 10.5 0.48 11.2 2.0 3.2 2 1 1 3 3 3 0 Occludin homology domain NPV_P10 PF05531.12 KPA35656.1 - 0.33 11.5 2.3 4.3 7.9 2.3 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 KPA35656.1 - 0.34 10.4 10.3 0.096 12.2 0.5 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit IFT57 PF10498.9 KPA35656.1 - 0.73 8.7 10.2 0.046 12.7 4.0 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 SF-assemblin PF06705.11 KPA35656.1 - 0.89 8.8 8.1 0.034 13.5 1.6 1.8 2 0 0 2 2 2 0 SF-assemblin/beta giardin DUF4618 PF15397.6 KPA35656.1 - 1.8 7.9 9.7 0.15 11.5 3.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Filament PF00038.21 KPA35656.1 - 1.8 8.0 12.6 4.3 6.8 3.9 2.6 2 1 0 2 2 2 0 Intermediate filament protein DUF948 PF06103.11 KPA35656.1 - 2 8.7 4.1 5.2 7.4 0.3 2.5 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) EzrA PF06160.12 KPA35656.1 - 3.3 5.8 8.5 0.84 7.7 0.1 2.0 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF16 PF01519.16 KPA35656.1 - 3.8 8.0 10.5 0.33 11.4 2.7 2.7 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF2959 PF11172.8 KPA35656.1 - 4.6 7.3 8.7 0.13 12.4 1.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) GAS PF13851.6 KPA35656.1 - 4.6 6.5 10.5 0.33 10.3 2.2 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding HET PF06985.11 KPA35657.1 - 0.00023 21.6 0.9 0.046 14.1 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 KPA35658.1 - 1.9e-15 56.8 0.0 3.3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPA35658.1 - 0.0083 16.2 0.0 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.16 KPA35659.1 - 7.4e-43 146.8 37.6 8.9e-43 146.6 37.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA35659.1 - 2.3e-12 46.5 4.5 2.3e-12 46.5 4.5 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPA35659.1 - 1.8e-07 30.0 2.2 3.3e-07 29.1 2.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Flavoprotein PF02441.19 KPA35660.1 - 6.1e-14 52.1 0.0 7.2e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein UbiD PF01977.16 KPA35661.1 - 1.3e-90 304.2 0.0 1.5e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Chromo PF00385.24 KPA35662.1 - 8.3e-09 35.2 5.2 3.9e-06 26.7 0.3 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4413 PF14372.6 KPA35663.1 - 0.072 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Dynactin_p22 PF07426.11 KPA35664.1 - 0.055 13.3 2.2 0.45 10.3 1.5 2.3 1 1 0 2 2 2 0 Dynactin subunit p22 NOG1_N PF17835.1 KPA35664.1 - 0.088 12.8 1.6 0.19 11.7 1.6 1.7 1 1 0 1 1 1 0 NOG1 N-terminal helical domain Hemocyanin_N PF03722.14 KPA35664.1 - 0.1 13.1 0.2 0.2 12.2 0.2 1.5 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain Cluap1 PF10234.9 KPA35664.1 - 0.14 11.5 6.4 0.074 12.4 4.3 1.6 2 0 0 2 2 2 0 Clusterin-associated protein-1 Cob_adeno_trans PF01923.18 KPA35664.1 - 0.18 11.9 2.5 11 6.1 0.1 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase APG6_N PF17675.1 KPA35664.1 - 0.28 11.7 11.5 2.1 8.8 4.7 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Sec2p PF06428.11 KPA35664.1 - 0.42 10.6 6.9 0.094 12.7 1.8 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p CCDC85 PF10226.9 KPA35664.1 - 0.75 9.5 7.2 0.096 12.4 2.7 1.8 2 0 0 2 2 2 0 CCDC85 family Helo_like_N PF17111.5 KPA35665.1 - 1.9e-68 230.0 0.4 3.2e-68 229.2 0.3 1.4 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins Med9 PF07544.13 KPA35665.1 - 0.003 17.6 0.8 1.6 8.9 0.0 3.5 4 0 0 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 KASH_CCD PF14662.6 KPA35665.1 - 0.0066 16.3 1.9 0.55 10.0 0.0 2.2 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH Phage_int_SAM_2 PF12834.7 KPA35665.1 - 0.04 14.6 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal Gly_radical PF01228.21 KPA35665.1 - 0.11 13.1 0.0 17 6.0 0.0 2.3 2 0 0 2 2 2 0 Glycine radical FeoB_Cyto PF17910.1 KPA35665.1 - 0.12 12.9 2.0 3.1 8.4 0.8 2.4 1 1 1 2 2 2 0 FeoB cytosolic helical domain NPV_P10 PF05531.12 KPA35665.1 - 0.15 12.5 2.9 2.2 8.8 0.3 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TolA_bind_tri PF16331.5 KPA35665.1 - 4.6 7.4 6.0 5.4 7.2 0.1 3.0 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF3945 PF13101.6 KPA35666.1 - 0.18 11.5 0.4 1.1 9.1 0.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3945) Sugar_tr PF00083.24 KPA35667.1 - 6.7e-76 256.0 23.2 8e-76 255.7 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA35667.1 - 7.7e-23 81.0 30.0 2.7e-18 66.0 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA35667.1 - 0.0011 17.5 2.8 0.0018 16.7 2.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_tranf_2_3 PF13641.6 KPA35668.1 - 8.5e-10 38.9 0.6 0.00039 20.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPA35668.1 - 9.1e-06 25.6 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KPA35668.1 - 0.015 14.8 0.5 0.09 12.3 0.3 2.3 2 1 0 2 2 2 0 Glycosyl transferase family 21 DDE_3 PF13358.6 KPA35671.1 - 7.1e-13 48.5 0.3 1.8e-12 47.2 0.3 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KPA35671.1 - 2.9e-07 30.7 0.5 5.3e-07 29.8 0.5 1.5 1 0 0 1 1 1 1 Transposase DDE_1 PF03184.19 KPA35671.1 - 0.0042 16.7 0.5 0.0078 15.9 0.5 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease Fungal_trans PF04082.18 KPA35672.1 - 4.7e-24 84.8 0.6 9.5e-24 83.8 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KPA35673.1 - 1.9e-22 79.7 11.7 1.9e-22 79.7 11.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2070 PF09843.9 KPA35673.1 - 0.0041 15.5 5.1 0.0068 14.8 5.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) TBP-binding PF09247.11 KPA35675.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 TATA box-binding protein binding adh_short_C2 PF13561.6 KPA35676.1 - 2.4e-54 184.4 0.4 3e-54 184.0 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA35676.1 - 4.9e-42 143.6 0.6 5.8e-42 143.4 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA35676.1 - 3.4e-10 40.1 0.1 5.6e-10 39.4 0.1 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA35676.1 - 9e-05 21.7 0.2 0.00011 21.4 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPA35676.1 - 0.02 14.4 0.1 0.044 13.2 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MMR_HSR1 PF01926.23 KPA35679.1 - 4.9e-09 36.3 0.0 2.1e-08 34.2 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA35679.1 - 6.3e-06 26.2 0.2 6.3e-06 26.2 0.2 2.8 2 1 2 4 4 4 1 RsgA GTPase FeoB_N PF02421.18 KPA35679.1 - 0.00019 21.0 1.8 0.0031 17.0 0.1 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.18 KPA35679.1 - 0.00031 20.1 0.0 0.00031 20.1 0.0 2.6 2 1 0 2 2 2 1 Septin IIGP PF05049.13 KPA35679.1 - 0.00033 19.8 0.1 0.00033 19.8 0.1 2.3 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 KPA35679.1 - 0.00037 19.9 0.1 0.00037 19.9 0.1 2.8 2 1 1 3 3 2 1 AIG1 family Dynamin_N PF00350.23 KPA35679.1 - 0.00039 20.5 1.2 0.0045 17.1 0.3 4.5 2 2 1 3 3 2 2 Dynamin family DUF1248 PF06852.12 KPA35679.1 - 0.0049 16.4 0.1 0.06 12.8 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1248) ABC_tran PF00005.27 KPA35679.1 - 0.0097 16.4 0.0 0.0097 16.4 0.0 3.0 2 1 0 2 2 1 1 ABC transporter Viral_helicase1 PF01443.18 KPA35679.1 - 0.02 14.6 0.8 0.038 13.7 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF3040 PF11239.8 KPA35679.1 - 0.022 15.0 0.3 0.022 15.0 0.3 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF3040) AAA_18 PF13238.6 KPA35679.1 - 0.088 13.3 8.7 0.12 12.9 0.0 3.4 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 KPA35679.1 - 0.095 12.5 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KPA35679.1 - 0.24 11.7 0.0 0.24 11.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain CRISPR_Cse1 PF09481.10 KPA35679.1 - 0.82 8.7 7.4 1.2 8.1 7.4 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) AAA_16 PF13191.6 KPA35679.1 - 4.2 7.7 0.0 4.2 7.7 0.0 3.1 2 1 0 2 2 1 0 AAA ATPase domain DUF3141 PF11339.8 KPA35679.1 - 4.7 5.5 12.7 6.6 5.0 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DUF3584 PF12128.8 KPA35679.1 - 7.7 3.9 38.1 11 3.4 38.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HET PF06985.11 KPA35680.1 - 2.1e-20 73.6 0.0 2.3e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N PF00107.26 KPA35681.1 - 3.7e-09 36.7 0.0 7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA35681.1 - 3.2e-06 27.0 0.1 5.7e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPA35681.1 - 3.7e-05 24.8 0.0 6.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPA35681.1 - 0.0024 17.7 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Tri3 PF07428.11 KPA35681.1 - 0.2 10.6 0.0 0.28 10.1 0.0 1.1 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 GRAM PF02893.20 KPA35682.1 - 7.5e-06 25.8 0.2 1.6e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 GRAM domain WD40 PF00400.32 KPA35683.1 - 4.2e-10 40.1 6.6 0.025 15.4 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat NSP2-B_epitope PF14757.6 KPA35683.1 - 0.026 14.2 0.2 0.044 13.5 0.2 1.2 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein SH PF01445.17 KPA35683.1 - 0.028 14.4 0.1 0.053 13.5 0.1 1.4 1 0 0 1 1 1 0 Viral small hydrophobic protein CPSF_A PF03178.15 KPA35683.1 - 0.12 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 CPSF A subunit region NB-ARC PF00931.22 KPA35686.1 - 1.6e-06 27.5 0.1 0.001 18.3 0.0 2.7 2 1 1 3 3 3 2 NB-ARC domain AAA_22 PF13401.6 KPA35686.1 - 0.0016 18.7 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_UL36 PF03586.13 KPA35686.1 - 0.016 14.6 0.1 0.054 12.8 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein TPR_10 PF13374.6 KPA35686.1 - 0.018 14.9 0.0 0.055 13.4 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_25 PF13481.6 KPA35686.1 - 0.024 14.2 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATG13 PF10033.9 KPA35686.1 - 0.037 13.7 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 13 AAA_16 PF13191.6 KPA35686.1 - 0.12 12.7 0.7 1.6 9.1 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain Spc7 PF08317.11 KPA35687.1 - 0.0026 16.7 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KPA35687.1 - 0.004 17.2 0.0 0.12 12.4 0.0 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KPA35687.1 - 0.0044 16.9 0.1 0.011 15.6 0.1 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Syntaxin_2 PF14523.6 KPA35687.1 - 0.0097 16.3 1.7 0.14 12.5 1.7 2.4 1 1 0 1 1 1 1 Syntaxin-like protein DUF2205 PF10224.9 KPA35687.1 - 0.013 15.5 0.4 0.53 10.3 0.1 2.6 2 1 0 2 2 2 0 Short coiled-coil protein CdvA PF18822.1 KPA35687.1 - 0.035 13.9 0.2 0.49 10.2 0.0 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF713 PF05218.14 KPA35687.1 - 0.037 13.7 0.0 0.13 12.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF713) SF-assemblin PF06705.11 KPA35687.1 - 0.07 12.5 0.9 2.9 7.2 0.3 2.0 1 1 1 2 2 2 0 SF-assemblin/beta giardin Allexi_40kDa PF05549.11 KPA35687.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein Lipoprotein_7 PF01540.16 KPA35687.1 - 0.088 12.1 0.4 0.18 11.1 0.4 1.4 1 1 0 1 1 1 0 Adhesin lipoprotein DUF1664 PF07889.12 KPA35687.1 - 0.093 12.8 0.1 4 7.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DLP_helical PF18709.1 KPA35687.1 - 0.19 10.9 1.2 0.27 10.4 1.2 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain DUF2781 PF10914.8 KPA35690.1 - 3.1e-26 92.6 4.2 3.5e-26 92.4 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Zn_clus PF00172.18 KPA35691.1 - 0.00076 19.5 8.2 0.0014 18.7 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LrgB PF04172.16 KPA35692.1 - 0.28 10.7 7.1 0.022 14.3 1.9 1.8 2 0 0 2 2 2 0 LrgB-like family Dynamin_N PF00350.23 KPA35693.1 - 5.5e-32 111.1 0.0 1.6e-31 109.7 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KPA35693.1 - 1.2e-12 47.6 0.0 4.8e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KPA35693.1 - 3.8e-06 26.9 0.1 1.2e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KPA35693.1 - 0.017 15.7 0.1 0.058 13.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 KPA35693.1 - 0.12 12.7 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KPA35693.1 - 0.18 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Ras family DUF4105 PF13387.6 KPA35694.1 - 0.00027 20.6 0.1 0.00048 19.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) DUF778 PF05608.12 KPA35694.1 - 0.0034 17.8 0.0 0.0074 16.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF778) Peptidase_C97 PF05903.14 KPA35694.1 - 0.0037 17.1 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KPA35694.1 - 0.016 15.5 0.3 0.24 11.7 0.3 2.3 1 1 0 1 1 1 0 Lecithin retinol acyltransferase Rieske PF00355.26 KPA35695.1 - 1.4e-12 47.4 0.0 2.6e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 KPA35695.1 - 0.00032 20.7 0.6 0.0011 18.9 0.6 2.2 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Octopine_DH PF02317.17 KPA35696.1 - 8.4e-20 71.4 0.0 1.2e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain F420_oxidored PF03807.17 KPA35696.1 - 2.8e-05 24.6 0.1 5.8e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KPA35696.1 - 3.3e-05 23.9 0.0 6.6e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Peptidase_M24 PF00557.24 KPA35697.1 - 4.2e-21 75.6 0.0 9.3e-21 74.5 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KPA35697.1 - 2.8e-20 73.3 0.0 5.1e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain AAA_16 PF13191.6 KPA35698.1 - 5.1e-07 30.2 0.9 3.7e-05 24.2 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain Phage_HK97_TLTM PF06120.11 KPA35698.1 - 0.056 12.6 1.8 0.093 11.9 1.8 1.3 1 0 0 1 1 1 0 Tail length tape measure protein AAA_23 PF13476.6 KPA35698.1 - 4.9 7.6 0.0 4.9 7.6 0.0 3.2 2 1 1 3 3 3 0 AAA domain Sugar_tr PF00083.24 KPA35700.1 - 5.5e-82 276.0 4.8 1.1e-81 275.1 4.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA35700.1 - 2.4e-18 66.2 34.0 6.4e-11 41.8 16.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily WSK PF03832.13 KPA35700.1 - 0.059 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 WSK motif Glyco_hydro_75 PF07335.11 KPA35701.1 - 2e-62 210.3 0.1 2.6e-62 209.9 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 LVIVD PF08309.11 KPA35702.1 - 4.3e-09 35.5 0.0 0.023 14.0 0.0 4.4 4 0 0 4 4 4 4 LVIVD repeat DHquinase_I PF01487.15 KPA35706.1 - 0.09 13.0 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Type I 3-dehydroquinase GREB1 PF15782.5 KPA35706.1 - 1.7 5.6 9.2 2.1 5.4 9.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM176 PF14851.6 KPA35706.1 - 3.2 7.4 10.4 0.88 9.2 2.9 2.2 2 0 0 2 2 2 0 FAM176 family DUF4551 PF15087.6 KPA35706.1 - 6.4 5.5 11.8 7.5 5.2 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pkinase PF00069.25 KPA35707.1 - 9.8e-23 80.9 0.0 1.5e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA35707.1 - 2.5e-11 43.4 0.0 5.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPA35707.1 - 0.0012 18.9 0.3 1.6 8.6 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family FHA PF00498.26 KPA35707.1 - 0.0036 17.6 0.1 0.0076 16.6 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 KPA35707.1 - 0.0088 15.4 0.0 0.025 13.9 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_N PF08240.12 KPA35708.1 - 5.6e-29 100.2 0.2 1e-28 99.4 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA35708.1 - 1.1e-16 60.9 0.0 2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPA35708.1 - 0.00019 21.0 0.0 0.00041 19.9 0.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 KPA35708.1 - 0.077 12.9 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 KPA35708.1 - 0.11 13.6 0.0 0.18 12.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NACHT PF05729.12 KPA35711.1 - 7.4e-10 39.0 0.0 2.9e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPA35711.1 - 3.8e-05 24.1 0.0 0.00024 21.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain p450 PF00067.22 KPA35713.1 - 2e-62 211.4 0.0 2.5e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4452 PF14618.6 KPA35715.1 - 0.042 13.7 0.0 0.049 13.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4452) FAD_binding_2 PF00890.24 KPA35718.1 - 3.9e-35 121.7 0.1 1.2e-34 120.1 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA35718.1 - 6.4e-09 35.4 0.1 0.0018 17.6 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPA35718.1 - 2.6e-08 33.7 0.0 2.6e-08 33.7 0.0 1.9 3 0 0 3 3 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA35718.1 - 3.6e-08 32.5 1.5 0.01 14.6 0.1 3.3 3 0 0 3 3 3 3 HI0933-like protein DAO PF01266.24 KPA35718.1 - 5.1e-07 29.6 1.6 6.3e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KPA35718.1 - 0.00035 19.8 1.8 0.0036 16.4 0.2 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KPA35718.1 - 0.0005 19.4 0.0 0.018 14.3 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KPA35718.1 - 0.0014 17.9 0.1 0.14 11.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA35718.1 - 0.0065 16.7 0.5 0.023 14.9 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KPA35718.1 - 0.039 14.4 0.0 0.098 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 KPA35718.1 - 0.047 12.9 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Fungal_trans PF04082.18 KPA35719.1 - 5.3e-22 78.1 0.1 6.9e-22 77.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phage_connect_1 PF05135.13 KPA35721.1 - 0.00084 19.8 2.2 0.0017 18.8 0.5 2.3 2 1 0 2 2 2 1 Phage gp6-like head-tail connector protein BTB PF00651.31 KPA35721.1 - 0.034 14.4 0.0 17 5.7 0.0 2.7 3 0 0 3 3 3 0 BTB/POZ domain SNF5 PF04855.12 KPA35721.1 - 0.072 12.9 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 CENP-F_N PF10481.9 KPA35722.1 - 0.015 15.0 0.5 0.018 14.7 0.5 1.1 1 0 0 1 1 1 0 Cenp-F N-terminal domain Lipase_GDSL PF00657.22 KPA35723.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase zf-met PF12874.7 KPA35725.1 - 0.00022 21.5 10.8 0.14 12.6 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KPA35725.1 - 0.004 17.9 11.2 0.09 13.7 0.2 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA35725.1 - 0.049 14.1 0.4 0.049 14.1 0.4 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type RBDV_coat PF06593.11 KPA35725.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein zf-C2H2_6 PF13912.6 KPA35725.1 - 0.36 10.9 10.0 5.4 7.1 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger NACHT PF05729.12 KPA35726.1 - 1.2e-07 31.8 0.0 2.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.7 KPA35726.1 - 0.00016 22.3 0.0 0.00043 20.9 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family KAP_NTPase PF07693.14 KPA35726.1 - 0.0005 19.4 0.1 0.025 13.8 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain AAA_16 PF13191.6 KPA35726.1 - 0.00082 19.8 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA35726.1 - 0.0042 17.4 0.0 0.027 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF676 PF05057.14 KPA35726.1 - 0.051 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_29 PF13555.6 KPA35726.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KPA35726.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPA35726.1 - 0.088 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KPA35726.1 - 0.16 12.5 0.0 0.43 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Retrotran_gag_2 PF14223.6 KPA35728.1 - 5.3e-06 26.1 0.2 2.5e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KPA35728.1 - 0.27 11.4 5.4 0.55 10.4 5.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KPA35728.1 - 0.42 10.5 5.6 0.67 9.8 5.6 1.3 1 0 0 1 1 1 0 Zinc knuckle FMN_dh PF01070.18 KPA35729.1 - 1e-114 383.2 0.0 1.2e-114 383.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KPA35729.1 - 0.00013 21.1 1.9 0.00062 18.9 1.0 2.2 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KPA35729.1 - 0.00022 20.7 0.4 0.00036 20.0 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KPA35729.1 - 0.0014 17.9 0.2 0.0021 17.3 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KPA35729.1 - 0.0019 17.6 0.5 0.64 9.3 0.2 2.1 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG SH3_12 PF18129.1 KPA35729.1 - 0.17 12.0 5.2 0.14 12.3 3.1 1.9 1 1 1 2 2 2 0 Xrn1 SH3-like domain AA_permease PF00324.21 KPA35730.1 - 3.3e-112 375.5 44.6 4.1e-112 375.2 44.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA35730.1 - 2.4e-19 69.5 47.1 3.2e-19 69.1 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease Phage_Coat_A PF05357.13 KPA35730.1 - 0.022 14.6 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Phage Coat Protein A BNR_4 PF15892.5 KPA35731.1 - 5.1e-35 121.2 4.2 1.1e-34 120.1 3.2 1.8 2 0 0 2 2 2 1 BNR repeat-containing family member SBBP PF06739.11 KPA35731.1 - 0.066 13.2 0.8 11 6.2 0.1 3.1 2 0 0 2 2 2 0 Beta-propeller repeat RelA_SpoT PF04607.17 KPA35732.1 - 6.1e-08 33.0 0.0 1.2e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins GRDP-like PF07173.12 KPA35733.1 - 0.00065 20.4 0.6 0.0022 18.7 0.6 1.8 2 0 0 2 2 2 1 Glycine-rich domain-containing protein-like Abhydrolase_6 PF12697.7 KPA35734.1 - 1.3e-07 32.5 0.0 3.2e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA35734.1 - 0.023 13.9 0.3 0.28 10.4 0.0 2.6 3 1 0 3 3 3 0 Serine aminopeptidase, S33 HMG-CoA_red PF00368.18 KPA35735.1 - 8.4e-136 452.8 3.0 1.2e-135 452.3 3.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KPA35735.1 - 5.8e-23 81.5 1.5 1.1e-22 80.5 1.5 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KPA35735.1 - 3.3e-09 36.8 2.0 7.6e-09 35.6 2.0 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KPA35735.1 - 3.9 5.4 10.1 0.35 8.9 5.5 1.4 2 0 0 2 2 2 0 Patched family Beta-lactamase PF00144.24 KPA35736.1 - 0.004 16.4 0.1 0.0067 15.7 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase JmjC PF02373.22 KPA35738.1 - 8e-17 61.7 0.0 1.7e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PK_C PF02887.16 KPA35738.1 - 0.091 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain Chitin_bind_1 PF00187.19 KPA35739.1 - 2.9e-09 37.2 31.7 8.9e-05 22.9 16.7 2.5 2 1 0 2 2 2 2 Chitin recognition protein Chitin_bind_1 PF00187.19 KPA35740.1 - 2.6e-39 133.4 270.1 4.4e-06 27.1 18.9 12.0 8 3 4 12 12 12 11 Chitin recognition protein adh_short PF00106.25 KPA35741.1 - 2.3e-23 82.7 0.0 3.8e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA35741.1 - 2.1e-15 56.9 0.0 4.1e-15 56.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA35741.1 - 9.2e-08 32.2 0.5 1.4e-07 31.6 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KPA35741.1 - 0.0017 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPA35741.1 - 0.011 15.6 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KPA35741.1 - 0.19 11.1 0.0 0.48 9.8 0.0 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Dynamin_N PF00350.23 KPA35742.1 - 5.3e-28 98.2 0.0 1.1e-27 97.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KPA35742.1 - 1.9e-23 83.1 0.1 3.8e-23 82.1 0.1 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KPA35742.1 - 4e-05 23.7 0.2 0.002 18.2 0.0 3.2 2 2 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KPA35742.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FliH PF02108.16 KPA35742.1 - 0.12 12.4 0.7 2 8.5 0.1 2.6 1 1 1 2 2 2 0 Flagellar assembly protein FliH Focal_AT PF03623.13 KPA35742.1 - 0.25 11.4 1.9 1.6 8.7 0.4 2.3 2 0 0 2 2 2 0 Focal adhesion targeting region OTT_1508_deam PF14441.6 KPA35743.1 - 2e-19 69.3 0.5 4.3e-19 68.3 0.5 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase APH PF01636.23 KPA35743.1 - 0.19 11.6 3.1 2.7 7.9 0.6 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Phage_int_SAM_1 PF02899.17 KPA35743.1 - 0.73 10.2 3.1 7.6 6.9 0.6 3.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain NiFe_hyd_3_EhaA PF17367.2 KPA35744.1 - 0.12 12.5 4.7 0.12 12.5 1.3 2.3 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A HET PF06985.11 KPA35745.1 - 3.3e-08 34.0 0.1 5.7e-06 26.7 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-C2H2_2 PF12756.7 KPA35746.1 - 0.027 14.8 0.1 0.053 13.9 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Tropomyosin PF00261.20 KPA35746.1 - 0.09 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Tropomyosin zf_UBZ PF18439.1 KPA35746.1 - 0.14 11.8 0.9 0.26 10.9 0.9 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger LysM PF01476.20 KPA35747.1 - 8.7e-06 25.7 0.1 14 5.9 0.0 4.5 4 0 0 4 4 4 3 LysM domain UPF0203 PF05254.12 KPA35747.1 - 0.037 14.3 13.9 6.3 7.1 0.1 4.7 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0203) DND1_DSRM PF14709.7 KPA35749.1 - 0.13 12.5 0.3 0.36 11.1 0.3 1.7 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 BTB PF00651.31 KPA35752.1 - 1.1e-05 25.7 0.2 0.0014 18.8 0.0 3.8 4 0 0 4 4 4 1 BTB/POZ domain adh_short PF00106.25 KPA35753.1 - 8.4e-07 28.6 0.3 9.4e-07 28.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA35753.1 - 5.7e-06 26.4 0.1 6.5e-06 26.2 0.1 1.0 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KPA35753.1 - 0.04 14.0 0.1 0.043 13.9 0.1 1.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KPA35753.1 - 0.044 12.9 0.1 0.049 12.7 0.1 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NUP PF06516.11 KPA35754.1 - 3.7e-106 354.9 0.0 4.2e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Sulfotransfer_4 PF17784.1 KPA35755.1 - 5.3e-68 229.1 0.1 6.3e-68 228.8 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPA35755.1 - 0.022 15.2 0.1 9.7 6.5 0.0 2.3 1 1 0 2 2 2 0 Sulfotransferase family 7tm_1 PF00001.21 KPA35756.1 - 7.6e-08 32.0 2.2 1e-07 31.6 2.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 KPA35756.1 - 1.5e-07 31.0 7.9 3.9e-07 29.6 7.4 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 KPA35756.1 - 0.56 10.3 2.9 0.37 10.9 0.1 2.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term APH PF01636.23 KPA35757.1 - 9.5e-14 51.9 0.4 1.4e-13 51.3 0.4 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Zn_clus PF00172.18 KPA35759.1 - 2.1e-06 27.7 11.2 6.4e-06 26.2 11.2 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA35759.1 - 2.2e-06 26.8 0.4 3.6e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain eIF3m_C_helix PF18005.1 KPA35759.1 - 0.03 14.0 2.7 0.073 12.8 2.7 1.6 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Period_C PF12114.8 KPA35761.1 - 0.08 12.5 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region zf-A20 PF01754.16 KPA35761.1 - 0.086 12.8 3.0 0.16 11.9 3.0 1.4 1 0 0 1 1 1 0 A20-like zinc finger Cyclin_N PF00134.23 KPA35763.1 - 4.3e-37 126.7 0.1 8.3e-37 125.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KPA35763.1 - 4.4e-11 42.9 0.0 2.3e-10 40.6 0.0 2.3 1 1 0 1 1 1 1 Cyclin, C-terminal domain P_C10 PF14974.6 KPA35763.1 - 0.039 14.0 0.1 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein C10 AMP-binding PF00501.28 KPA35764.1 - 2.2e-58 197.8 0.0 2.7e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA35764.1 - 2.8e-15 57.1 0.1 5.2e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Tyrosinase PF00264.20 KPA35765.1 - 2.3e-13 51.0 0.3 3.7e-13 50.3 0.3 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF4413 PF14372.6 KPA35766.1 - 0.071 13.5 0.0 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Chromo PF00385.24 KPA35768.1 - 1.5e-06 28.0 0.4 0.0011 18.8 0.0 2.5 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KPA35768.1 - 0.037 14.1 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Chromo shadow domain Tudor_3 PF18115.1 KPA35768.1 - 0.042 13.7 0.2 5 7.0 0.0 2.4 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Ank_2 PF12796.7 KPA35769.1 - 4.4e-39 132.9 10.5 3.9e-14 53.0 1.3 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA35769.1 - 7.2e-28 96.6 9.0 8.4e-08 32.6 0.2 5.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA35769.1 - 1.4e-26 92.2 7.2 1.2e-06 28.7 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KPA35769.1 - 2.9e-25 87.5 18.5 0.00016 21.9 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KPA35769.1 - 9.7e-23 77.8 5.4 0.022 15.3 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat Tannase PF07519.11 KPA35772.1 - 2.5e-09 36.6 0.1 3.2e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase zf-3CxxC PF13695.6 KPA35773.1 - 4.6e-24 84.8 1.8 6e-24 84.4 1.8 1.1 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 KPA35773.1 - 0.026 15.2 4.0 0.9 10.3 0.9 2.7 2 1 0 2 2 2 0 Zinc-binding domain p450 PF00067.22 KPA35774.1 - 4.9e-17 61.8 0.0 1.3e-07 30.8 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 Patatin PF01734.22 KPA35777.1 - 9.5e-23 81.4 0.0 1.4e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase RBB1NT PF08169.11 KPA35777.1 - 0.18 12.0 0.2 0.46 10.7 0.0 1.8 2 0 0 2 2 2 0 RBB1NT (NUC162) domain AA_permease_2 PF13520.6 KPA35780.1 - 3.7e-43 148.0 14.6 2.9e-41 141.7 14.5 3.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA35780.1 - 0.0007 18.3 3.3 0.0007 18.3 3.3 3.8 4 1 0 4 4 4 2 Amino acid permease DAO PF01266.24 KPA35781.1 - 1.4e-29 103.8 0.5 1.6e-29 103.6 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pkinase PF00069.25 KPA35784.1 - 4.9e-06 26.1 0.0 9.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KPA35784.1 - 0.007 15.7 0.7 0.022 14.1 0.2 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Radial_spoke_3 PF06098.11 KPA35784.1 - 0.19 11.0 5.9 0.25 10.6 4.3 2.0 2 0 0 2 2 2 0 Radial spoke protein 3 APH PF01636.23 KPA35784.1 - 0.42 10.5 11.0 4.8 7.0 0.0 3.6 3 1 1 4 4 4 0 Phosphotransferase enzyme family FAD_binding_3 PF01494.19 KPA35785.1 - 9.5e-21 74.4 0.0 1.4e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA35785.1 - 1e-10 41.8 0.0 0.00013 21.7 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA35785.1 - 2.6e-07 30.2 0.0 0.0082 15.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA35785.1 - 0.00081 19.6 0.1 0.0018 18.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPA35785.1 - 0.0026 18.3 0.2 0.41 11.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KPA35785.1 - 0.031 13.9 0.1 0.098 12.3 0.0 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA G6B PF15096.6 KPA35785.1 - 0.071 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 G6B family TrkA_N PF02254.18 KPA35785.1 - 0.1 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Abhydrolase_6 PF12697.7 KPA35786.1 - 0.023 15.3 0.0 0.034 14.8 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA35786.1 - 0.035 13.8 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KPA35786.1 - 0.057 13.3 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA35786.1 - 0.1 11.9 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LysM PF01476.20 KPA35787.1 - 4.1e-06 26.7 0.0 1.1e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 LysM domain DUF3819 PF12842.7 KPA35788.1 - 0.047 13.6 0.8 0.15 12.0 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3819) DnaB_2 PF07261.11 KPA35788.1 - 0.093 12.5 0.1 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Replication initiation and membrane attachment Sec34 PF04136.15 KPA35788.1 - 0.16 11.8 2.3 0.29 11.0 0.1 2.3 2 1 1 3 3 3 0 Sec34-like family DUF948 PF06103.11 KPA35788.1 - 6.5 7.1 7.7 5.5 7.3 3.2 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BatD PF13584.6 KPA35789.1 - 0.00012 21.1 0.4 0.00017 20.6 0.4 1.1 1 0 0 1 1 1 1 Oxygen tolerance Podoplanin PF05808.11 KPA35789.1 - 0.0011 19.0 0.8 0.0018 18.4 0.8 1.4 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.11 KPA35789.1 - 0.013 16.0 4.8 0.021 15.3 4.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Amnionless PF14828.6 KPA35789.1 - 0.031 13.1 0.4 0.048 12.5 0.0 1.5 2 0 0 2 2 2 0 Amnionless TMEM154 PF15102.6 KPA35789.1 - 0.041 13.8 0.2 0.075 12.9 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family Peptidase_M56 PF05569.11 KPA35789.1 - 0.081 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 EphA2_TM PF14575.6 KPA35789.1 - 0.12 13.2 0.0 0.33 11.9 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 KPA35789.1 - 1.9 7.3 7.5 2.5 6.9 6.5 1.5 1 1 0 1 1 1 0 Giardia variant-specific surface protein PNP_UDP_1 PF01048.20 KPA35790.1 - 1.3e-10 41.0 0.0 2.4e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KPA35790.1 - 4e-05 23.6 0.0 9.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 KPA35790.1 - 0.00063 20.3 0.0 0.0024 18.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) AAA_16 PF13191.6 KPA35790.1 - 0.0032 17.9 0.0 0.014 15.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA35790.1 - 0.01 16.1 0.0 0.029 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ank_4 PF13637.6 KPA35790.1 - 0.015 15.9 0.1 0.05 14.2 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) SMODS PF18144.1 KPA35790.1 - 0.13 12.4 0.0 4.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain ABC_tran PF00005.27 KPA35790.1 - 0.13 12.7 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Ank_3 PF13606.6 KPA35790.1 - 0.16 12.6 1.8 54 4.9 0.1 3.8 3 0 0 3 3 3 0 Ankyrin repeat CBM_4_9 PF02018.17 KPA35791.1 - 4.3e-07 30.3 0.4 7.4e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Carbohydrate binding domain DAO PF01266.24 KPA35792.1 - 7.1e-42 144.2 1.8 8e-42 144.1 1.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA35792.1 - 1.1e-07 31.4 0.3 0.00049 19.4 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA35792.1 - 6.1e-05 23.1 0.4 0.023 14.7 0.2 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KPA35792.1 - 8.5e-05 21.8 3.9 0.17 10.9 3.9 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KPA35792.1 - 0.0007 18.8 4.2 0.024 13.7 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KPA35792.1 - 0.0013 19.2 0.3 0.004 17.6 0.0 2.0 2 1 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 KPA35792.1 - 0.0013 17.7 2.4 0.034 13.0 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KPA35792.1 - 0.0022 17.2 1.3 0.54 9.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPA35792.1 - 0.0048 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 KPA35792.1 - 0.012 15.0 0.2 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase TrkA_N PF02254.18 KPA35792.1 - 0.019 15.2 0.1 0.075 13.3 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KPA35792.1 - 0.019 14.3 0.4 0.057 12.7 0.4 1.8 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1188 PF06690.11 KPA35792.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Mqo PF06039.15 KPA35792.1 - 0.023 13.3 1.0 0.11 11.1 0.2 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 KPA35792.1 - 0.045 13.0 3.3 0.39 9.9 0.3 2.7 3 0 0 3 3 3 0 Thi4 family HI0933_like PF03486.14 KPA35792.1 - 0.048 12.4 0.2 0.048 12.4 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein DMPK_coil PF08826.10 KPA35792.1 - 0.21 11.7 2.8 1.5 9.0 0.9 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like Glyco_hydro_39 PF01229.17 KPA35795.1 - 0.006 15.2 0.0 0.0083 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 CVNH PF08881.10 KPA35798.1 - 3.8e-28 98.1 0.0 4.3e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 CVNH domain Head_binding PF09008.10 KPA35798.1 - 0.18 12.1 0.2 10 6.4 0.1 2.1 2 0 0 2 2 2 0 Head binding TPR_MLP1_2 PF07926.12 KPA35799.1 - 0.0088 16.1 5.8 0.0088 16.1 5.8 2.0 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein Dynamin_M PF01031.20 KPA35799.1 - 0.031 13.5 2.8 0.053 12.7 2.3 1.6 1 1 0 1 1 1 0 Dynamin central region EcoR124_C PF12008.8 KPA35799.1 - 0.058 13.0 1.6 0.085 12.5 1.6 1.3 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal Vps51 PF08700.11 KPA35799.1 - 0.11 12.6 6.8 0.15 12.2 3.8 2.6 1 1 1 3 3 3 0 Vps51/Vps67 DUF1640 PF07798.11 KPA35799.1 - 0.14 12.2 10.2 0.044 13.8 7.2 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) GIT1_C PF12205.8 KPA35799.1 - 0.37 10.9 3.7 28 4.8 3.0 2.5 2 1 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term MCPsignal PF00015.21 KPA35799.1 - 0.38 10.5 8.8 0.27 11.0 3.7 2.6 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Jnk-SapK_ap_N PF09744.9 KPA35799.1 - 0.44 10.8 9.9 0.049 13.8 4.9 2.0 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 KPA35799.1 - 1.3 9.4 11.6 0.076 13.5 5.2 1.9 2 0 0 2 2 2 0 Fez1 Exonuc_VII_L PF02601.15 KPA35799.1 - 1.7 8.1 9.8 2.9 7.4 9.7 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Cor1 PF04803.12 KPA35799.1 - 2.5 8.3 10.7 3 8.1 7.9 2.5 1 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Asp PF00026.23 KPA35802.1 - 1.4e-32 113.4 0.5 1.7e-32 113.1 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA35802.1 - 0.00052 20.3 1.5 0.078 13.2 0.0 2.7 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal 2-oxoacid_dh PF00198.23 KPA35803.1 - 1.2e-80 270.3 0.1 1.7e-80 269.8 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KPA35803.1 - 8e-16 57.6 2.2 1.6e-15 56.6 2.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KPA35803.1 - 0.19 11.6 1.6 5.8 6.8 0.1 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like Trypan_PARP PF05887.11 KPA35803.1 - 0.32 11.0 13.7 0.51 10.3 13.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Presenilin PF01080.17 KPA35803.1 - 0.54 9.0 7.4 0.78 8.4 7.4 1.1 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 KPA35803.1 - 0.74 8.6 6.9 0.97 8.2 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF2052 PF09747.9 KPA35803.1 - 1.2 9.2 9.3 1.9 8.6 9.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Apt1 PF10351.9 KPA35803.1 - 1.8 7.3 8.2 2.4 6.9 8.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM76 PF16046.5 KPA35803.1 - 2.4 7.4 9.0 4 6.7 6.0 2.0 2 0 0 2 2 2 0 FAM76 protein Ndc1_Nup PF09531.10 KPA35803.1 - 2.6 6.6 5.1 3.4 6.2 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 KPA35803.1 - 5.6 6.7 10.2 7.8 6.2 10.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 KPA35803.1 - 6.3 5.7 9.8 15 4.4 0.1 2.1 2 0 0 2 2 2 0 Solute carrier family 12 CDC45 PF02724.14 KPA35803.1 - 6.6 4.9 8.2 8.7 4.5 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1772 PF08592.11 KPA35805.1 - 1.1e-11 45.2 1.7 1.4e-11 44.9 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.6 KPA35805.1 - 0.021 13.9 0.3 0.028 13.5 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Zn_clus PF00172.18 KPA35806.1 - 6.4e-10 39.0 14.5 1.5e-09 37.8 14.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA35806.1 - 1.6e-06 27.4 0.1 6.6e-06 25.3 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Haem_degrading PF03928.14 KPA35807.1 - 1.3e-14 54.3 0.4 1.5e-14 54.1 0.4 1.0 1 0 0 1 1 1 1 Haem-degrading TPR_12 PF13424.6 KPA35809.1 - 6.3e-11 42.4 0.1 1.6e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KPA35809.1 - 9.9e-11 41.2 2.2 5.9e-05 22.8 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat NACHT PF05729.12 KPA35809.1 - 2e-08 34.3 0.0 3.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KPA35809.1 - 4.1e-08 32.7 0.0 1.2e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain DUF676 PF05057.14 KPA35809.1 - 7.6e-05 22.3 0.0 0.00021 20.9 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.6 KPA35809.1 - 0.00014 22.1 0.0 0.00046 20.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA35809.1 - 0.00033 21.1 0.1 0.0016 18.8 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain TPR_19 PF14559.6 KPA35809.1 - 0.00055 20.4 0.2 0.0023 18.4 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat SRP54 PF00448.22 KPA35809.1 - 0.0037 16.9 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Spt4 PF06093.13 KPA35809.1 - 0.0079 16.3 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TPR_20 PF14561.6 KPA35809.1 - 0.014 15.7 0.4 0.16 12.3 0.2 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF829 PF05705.14 KPA35809.1 - 0.029 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) TPR_7 PF13176.6 KPA35809.1 - 0.039 14.0 0.0 0.31 11.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA35809.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Abhydrolase_6 PF12697.7 KPA35809.1 - 0.048 14.3 0.1 7 7.2 0.0 2.8 3 0 0 3 3 3 0 Alpha/beta hydrolase family TPR_14 PF13428.6 KPA35809.1 - 0.077 13.9 2.8 0.56 11.2 0.0 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPA35809.1 - 0.13 12.5 0.0 1 9.6 0.0 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KPA35809.1 - 0.13 12.5 0.0 0.7 10.2 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPA35809.1 - 0.66 10.8 3.5 9.1 7.2 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat CDH-cyt PF16010.5 KPA35810.1 - 8e-48 162.5 0.0 9.8e-48 162.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase tRNA-synt_1b PF00579.25 KPA35811.1 - 1.5e-21 77.0 0.0 2.3e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CDH-cyt PF16010.5 KPA35811.1 - 1.5e-15 57.4 3.8 3e-15 56.4 3.8 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 KPA35811.1 - 0.0037 17.0 1.3 0.0037 17.0 1.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 KPA35811.1 - 0.36 11.0 6.1 1.4 9.1 5.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Zn_clus PF00172.18 KPA35812.1 - 6.1e-06 26.3 12.1 1.3e-05 25.2 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 KPA35813.1 - 1.9e-13 50.4 0.1 5e-13 49.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA35813.1 - 5.3e-11 42.1 0.0 1.3e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KPA35813.1 - 1.2e-10 41.6 0.0 1.8e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KPA35813.1 - 7e-09 35.5 0.2 5.9e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KPA35813.1 - 2.3e-08 33.9 0.1 3.5e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KPA35813.1 - 1.6e-07 30.7 0.5 8.5e-06 25.1 0.5 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KPA35813.1 - 1.3e-06 27.8 0.0 2e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KPA35813.1 - 0.00027 20.5 0.0 0.002 17.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KPA35813.1 - 0.013 14.6 0.1 0.07 12.2 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 KPA35813.1 - 0.055 13.4 1.1 1.4 8.8 1.1 2.3 1 1 0 1 1 1 0 KR domain Peptidase_S66 PF02016.15 KPA35815.1 - 5.8e-27 94.2 0.0 7.2e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain zf-BED PF02892.15 KPA35816.1 - 0.048 13.7 2.6 0.11 12.6 2.6 1.6 1 0 0 1 1 1 0 BED zinc finger Chromo PF00385.24 KPA35817.1 - 1e-06 28.5 1.4 1e-05 25.3 0.2 2.6 2 2 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 KPA35818.1 - 5.2e-10 39.5 0.3 7.1e-10 39.0 0.3 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein PRK PF00485.18 KPA35818.1 - 0.047 13.4 0.2 0.052 13.3 0.2 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Sugar_tr PF00083.24 KPA35819.1 - 5.6e-82 276.0 21.3 6.5e-82 275.8 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA35819.1 - 1.3e-19 70.4 20.5 1.3e-19 70.4 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Response_reg PF00072.24 KPA35822.1 - 7.7e-19 67.9 0.0 1.6e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KPA35822.1 - 5.6e-13 49.4 0.0 1e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KPA35822.1 - 1.9e-11 43.9 0.1 5.9e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KPA35822.1 - 0.036 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Innexin PF00876.18 KPA35823.1 - 1.5 8.0 5.3 0.63 9.3 3.0 1.4 2 0 0 2 2 2 0 Innexin NUC173 PF08161.12 KPA35824.1 - 0.011 15.5 0.1 0.047 13.4 0.1 1.9 2 0 0 2 2 2 0 NUC173 domain EST1_DNA_bind PF10373.9 KPA35824.1 - 0.13 11.7 0.5 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain Dynamin_N PF00350.23 KPA35826.1 - 2.5e-33 115.5 1.0 5.1e-33 114.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KPA35826.1 - 4.5e-14 52.3 0.1 1.5e-06 27.7 0.0 3.6 3 0 0 3 3 3 3 Dynamin central region MMR_HSR1 PF01926.23 KPA35826.1 - 2e-05 24.7 1.4 0.003 17.6 0.1 3.6 2 2 1 3 3 3 1 50S ribosome-binding GTPase GED PF02212.18 KPA35826.1 - 8.8e-05 22.6 0.1 0.00048 20.2 0.1 2.4 1 1 0 1 1 1 1 Dynamin GTPase effector domain FeoB_N PF02421.18 KPA35826.1 - 0.083 12.4 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 KPA35826.1 - 0.13 12.5 0.0 0.41 10.9 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DPPIV_rep PF18811.1 KPA35826.1 - 0.14 12.1 0.4 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) low complexity region Abhydrolase_1 PF00561.20 KPA35827.1 - 6.3e-21 75.2 0.2 7.7e-20 71.6 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA35827.1 - 3.8e-12 47.3 0.2 5.9e-12 46.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA35827.1 - 1.6e-11 44.0 0.0 2.1e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 KPA35827.1 - 5.7e-05 21.9 0.0 8.5e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family AXE1 PF05448.12 KPA35827.1 - 0.064 11.9 0.0 0.43 9.2 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF5488 PF17590.2 KPA35828.1 - 0.012 15.4 2.6 0.1 12.3 1.1 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5488) TraS PF10624.9 KPA35828.1 - 0.22 11.5 0.7 0.35 10.8 0.5 1.5 1 1 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Strabismus PF06638.11 KPA35828.1 - 0.42 9.2 2.0 0.6 8.7 2.0 1.2 1 0 0 1 1 1 0 Strabismus protein zf-C2H2_8 PF15909.5 KPA35829.1 - 0.011 16.0 0.0 0.051 13.9 0.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc ribbon TENA_THI-4 PF03070.16 KPA35830.1 - 0.00013 21.9 0.0 0.00048 20.0 0.0 1.9 1 1 0 1 1 1 1 TENA/THI-4/PQQC family NmrA PF05368.13 KPA35831.1 - 1.5e-54 185.0 0.7 1.9e-54 184.7 0.7 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA35831.1 - 7.3e-18 65.1 0.1 9.2e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KPA35831.1 - 0.00011 21.3 0.1 0.00016 20.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPA35831.1 - 0.0099 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KPA35831.1 - 0.05 14.0 0.4 5.4 7.5 0.3 3.2 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KPA35831.1 - 0.068 13.4 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HET PF06985.11 KPA35832.1 - 2.5e-21 76.6 0.0 3.8e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4083 PF13314.6 KPA35833.1 - 0.36 10.8 0.1 0.36 10.8 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4083) COesterase PF00135.28 KPA35834.1 - 7.9e-81 272.5 0.1 4.7e-71 240.2 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family RhoGEF PF00621.20 KPA35834.1 - 7.3e-32 111.1 0.9 3.6e-31 108.8 0.4 2.0 2 0 0 2 2 2 1 RhoGEF domain Abhydrolase_3 PF07859.13 KPA35834.1 - 9.6e-12 45.2 0.0 2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_76 PF03663.14 KPA35836.1 - 9.8e-148 492.5 8.5 1.1e-147 492.3 8.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Mer2 PF09074.10 KPA35837.1 - 0.058 13.2 1.6 0.078 12.8 1.6 1.3 1 0 0 1 1 1 0 Mer2 RVT_thumb PF06817.14 KPA35837.1 - 0.077 12.8 0.0 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Reverse transcriptase thumb domain APH PF01636.23 KPA35838.1 - 4.7e-10 39.8 0.0 4.6e-09 36.5 0.0 2.5 2 2 0 3 3 3 1 Phosphotransferase enzyme family Trm5_N PF18093.1 KPA35839.1 - 0.0046 16.8 0.4 0.0073 16.2 0.4 1.3 1 0 0 1 1 1 1 tRNA methyltransferase 5 N-terminal domain DUF3435 PF11917.8 KPA35840.1 - 9.1e-60 202.7 0.4 9.1e-60 202.7 0.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) RRP36 PF06102.12 KPA35840.1 - 0.001 19.1 4.2 0.0028 17.6 4.2 1.7 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 Zn_clus PF00172.18 KPA35843.1 - 2.7e-09 37.0 6.4 6e-09 35.9 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 KPA35843.1 - 0.075 12.8 2.0 0.13 12.0 0.9 1.9 2 0 0 2 2 2 0 Integrin plexin domain FCD PF07729.12 KPA35843.1 - 0.13 12.7 0.7 0.25 11.8 0.7 1.4 1 0 0 1 1 1 0 FCD domain p450 PF00067.22 KPA35845.1 - 4.2e-27 95.0 0.0 4.9e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CMAS PF02353.20 KPA35846.1 - 6.6e-60 202.7 0.4 8.2e-60 202.4 0.4 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KPA35846.1 - 2.2e-10 40.6 0.0 3.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA35846.1 - 6.4e-10 39.6 0.0 1.3e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA35846.1 - 6.9e-10 39.4 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA35846.1 - 4.5e-06 27.3 0.0 8.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA35846.1 - 0.00022 21.1 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA35846.1 - 0.00033 20.2 0.0 0.00062 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KPA35846.1 - 0.003 17.3 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KPA35846.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KPA35846.1 - 0.052 13.5 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KPA35846.1 - 0.059 12.9 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Sugar_tr PF00083.24 KPA35847.1 - 2.8e-30 105.6 13.3 3.2e-30 105.4 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA35847.1 - 5.5e-13 48.6 18.2 4.8e-12 45.5 16.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 KPA35847.1 - 8.2e-05 21.8 1.5 8.5e-05 21.7 1.5 1.2 1 0 0 1 1 1 1 PUCC protein MFS_2 PF13347.6 KPA35847.1 - 0.00078 18.1 1.3 0.00088 17.9 1.3 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KPA35848.1 - 3.4e-31 108.5 27.5 4.3e-31 108.1 27.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA35848.1 - 0.00015 20.8 23.3 0.00085 18.3 23.3 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter HET PF06985.11 KPA35849.1 - 1.1e-26 93.9 0.8 1.8e-26 93.2 0.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 KPA35850.1 - 2.8e-57 194.0 1.7 3.5e-57 193.7 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA35850.1 - 1.3e-52 178.2 0.1 1.7e-52 177.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA35850.1 - 1.2e-10 41.6 0.1 1.8e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA35850.1 - 0.00015 21.3 0.1 0.00054 19.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 KPA35850.1 - 0.0024 18.4 0.1 0.0045 17.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.15 KPA35850.1 - 0.0061 15.7 0.0 0.0073 15.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 KPA35850.1 - 0.0064 15.8 0.1 0.013 14.8 0.1 1.5 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 KPA35850.1 - 0.0073 16.2 0.1 0.0097 15.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Pyr_redox_2 PF07992.14 KPA35850.1 - 0.028 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 KPA35850.1 - 0.035 13.5 0.0 0.078 12.4 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 KPA35850.1 - 0.041 14.0 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.15 KPA35850.1 - 0.13 12.1 0.4 0.3 10.9 0.4 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 KPA35850.1 - 0.15 11.9 0.3 0.25 11.2 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4646 PF15496.6 KPA35851.1 - 0.0042 17.7 0.0 0.011 16.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) Bacteriocin_IIc PF10439.9 KPA35851.1 - 0.083 13.0 11.6 0.085 13.0 8.8 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.6 KPA35851.1 - 1.8 8.4 12.0 4.1 7.3 12.0 1.7 1 0 0 1 1 1 0 Glycine-zipper domain HET PF06985.11 KPA35852.1 - 1.3e-12 48.3 5.0 4.3e-11 43.4 0.8 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Lbh PF15317.6 KPA35852.1 - 0.14 13.0 0.0 0.59 11.0 0.0 2.0 2 0 0 2 2 2 0 Cardiac transcription factor regulator, Developmental protein Methyltransf_23 PF13489.6 KPA35853.1 - 6.9e-18 65.0 0.0 1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA35853.1 - 6.4e-14 52.4 0.0 4.6e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA35853.1 - 2.1e-11 44.3 0.0 6.2e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA35853.1 - 1.1e-08 35.8 0.0 5.2e-08 33.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA35853.1 - 5.4e-08 32.8 0.0 0.002 17.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KPA35853.1 - 6.9e-05 22.5 0.0 0.00017 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KPA35853.1 - 0.00031 20.1 0.0 0.0048 16.3 0.0 2.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KPA35853.1 - 0.0014 18.0 0.0 0.0036 16.6 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_16 PF10294.9 KPA35853.1 - 0.0022 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase CMAS PF02353.20 KPA35853.1 - 0.0035 16.7 0.0 0.0066 15.8 0.0 1.6 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KPA35853.1 - 0.0046 17.1 0.0 0.099 12.7 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase PrmA PF06325.13 KPA35853.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KPA35853.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) partial_CstF PF15861.5 KPA35853.1 - 0.13 12.1 0.4 0.28 11.0 0.4 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Methyltransf_4 PF02390.17 KPA35853.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.22 KPA35855.1 - 2e-32 112.6 0.0 2.5e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Bse634I PF07832.11 KPA35855.1 - 0.0056 16.1 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Cfr10I/Bse634I restriction endonuclease ELFV_dehydrog PF00208.21 KPA35856.1 - 4.3e-10 39.7 0.0 7.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Glyoxalase_4 PF13669.6 KPA35856.1 - 2.8e-06 27.5 0.0 6.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ELFV_dehydrog_N PF02812.18 KPA35856.1 - 1.7e-05 24.7 0.0 3.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Glyoxalase PF00903.25 KPA35856.1 - 0.00091 19.4 0.1 0.0024 18.0 0.1 1.8 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ADP_ribosyl_GH PF03747.14 KPA35857.1 - 7.8e-61 206.4 0.8 9e-61 206.1 0.8 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Epimerase PF01370.21 KPA35858.1 - 1.9e-19 70.1 0.0 3.2e-19 69.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA35858.1 - 1.6e-11 43.7 0.0 2.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPA35858.1 - 5.1e-11 42.2 0.0 2.1e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KPA35858.1 - 3.7e-10 39.7 0.0 1.9e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KPA35858.1 - 4e-07 30.1 0.1 3e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KPA35858.1 - 0.00011 21.9 0.4 0.00046 19.8 0.4 2.0 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KPA35858.1 - 0.00035 19.8 0.0 0.00054 19.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KPA35858.1 - 0.0032 17.0 0.1 0.0065 15.9 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA35858.1 - 0.011 15.6 0.5 0.34 10.8 0.4 2.4 2 1 0 2 2 2 0 KR domain Gpr1_Fun34_YaaH PF01184.19 KPA35860.1 - 4.6e-38 130.9 20.4 5.4e-38 130.7 20.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2157 PF09925.9 KPA35860.1 - 1 9.2 8.4 3.4 7.4 7.8 2.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF3784 PF12650.7 KPA35861.1 - 0.01 16.0 4.2 0.01 16.0 4.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3784) DUF2070 PF09843.9 KPA35861.1 - 4.6 5.4 11.5 6.5 4.9 11.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Oxidored_FMN PF00724.20 KPA35862.1 - 9e-41 140.3 0.0 1.2e-40 139.9 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Adeno_PVIII PF01310.18 KPA35862.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII HET PF06985.11 KPA35863.1 - 3.4e-09 37.2 1.0 1.2e-06 28.9 0.0 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Fic PF02661.18 KPA35865.1 - 5.7e-08 33.6 0.1 1.4e-07 32.3 0.0 1.7 2 0 0 2 2 2 1 Fic/DOC family Fungal_trans PF04082.18 KPA35866.1 - 0.00058 19.0 0.0 0.0015 17.6 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain MTD PF01993.18 KPA35866.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase adh_short PF00106.25 KPA35867.1 - 3.3e-12 46.3 0.1 2.7e-09 36.8 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA35867.1 - 2.5e-07 30.5 0.0 1.2e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Esterase_phd PF10503.9 KPA35868.1 - 4.3e-23 82.0 0.5 5.8e-23 81.5 0.5 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KPA35868.1 - 4.1e-10 39.5 2.1 5.7e-10 39.0 2.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KPA35868.1 - 0.00031 20.7 0.1 0.00046 20.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KPA35868.1 - 0.00048 19.8 0.5 0.00065 19.4 0.5 1.3 1 0 0 1 1 1 1 Putative esterase COesterase PF00135.28 KPA35868.1 - 0.0012 17.8 0.5 0.0023 16.9 0.5 1.4 1 0 0 1 1 1 1 Carboxylesterase family Eno-Rase_NADH_b PF12242.8 KPA35868.1 - 0.0024 17.6 0.5 0.014 15.1 0.1 2.2 1 1 1 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Hydrolase_4 PF12146.8 KPA35868.1 - 0.018 14.3 0.1 0.059 12.6 0.1 1.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 KPA35868.1 - 0.029 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KPA35868.1 - 0.035 13.7 1.1 0.084 12.4 1.1 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KPA35868.1 - 0.038 13.6 1.7 0.071 12.7 0.8 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KPA35868.1 - 0.085 12.6 0.0 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase HNH_2 PF13391.6 KPA35869.1 - 3.6e-17 62.2 0.0 8.3e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease HTH_Tnp_Tc5 PF03221.16 KPA35871.1 - 8.9e-07 28.8 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF2934 PF11154.8 KPA35871.1 - 0.0057 16.3 0.0 0.036 13.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2934) Epimerase PF01370.21 KPA35873.1 - 0.0017 17.8 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPA35873.1 - 0.2 10.8 0.0 8.7 5.4 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein DEAD PF00270.29 KPA35874.1 - 2.4e-22 79.5 0.0 5.7e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA35874.1 - 8.9e-19 67.9 0.2 1.6e-14 54.1 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KPA35874.1 - 1.1e-16 61.3 6.0 3.2e-16 59.8 6.0 1.9 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 KPA35874.1 - 4.9e-12 45.6 0.1 1.5e-11 44.1 0.1 1.9 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 KPA35874.1 - 1.5e-07 31.6 0.0 3.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.23 KPA35874.1 - 3e-05 23.9 0.1 8.6e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 HRDC domain SecA_DEAD PF07517.14 KPA35874.1 - 0.16 11.2 1.1 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain YpjP PF14005.6 KPA35875.1 - 0.00034 20.7 0.0 0.00053 20.0 0.0 1.2 1 0 0 1 1 1 1 YpjP-like protein Helo_like_N PF17111.5 KPA35875.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Zn_clus PF00172.18 KPA35877.1 - 1.4e-06 28.3 10.5 2.1e-06 27.7 10.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 KPA35878.1 - 8.4e-30 103.9 0.0 4.2e-14 53.1 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 KPA35878.1 - 2.6e-12 46.7 1.7 4.1e-11 42.9 0.1 3.5 4 0 0 4 4 3 1 AAA lid domain AAA_5 PF07728.14 KPA35878.1 - 2.7e-08 33.9 0.0 0.0057 16.6 0.0 3.8 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KPA35878.1 - 9.6e-08 32.0 0.6 0.00091 19.0 0.0 3.1 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 KPA35878.1 - 5.5e-07 29.9 6.7 0.78 10.0 0.1 5.9 4 2 0 5 5 5 2 AAA domain RuvB_N PF05496.12 KPA35878.1 - 1e-05 25.3 0.0 0.034 13.9 0.0 3.2 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPA35878.1 - 7.4e-05 23.2 4.1 0.7 10.3 0.1 4.3 4 1 0 4 4 4 2 AAA ATPase domain AAA_19 PF13245.6 KPA35878.1 - 0.00035 20.9 0.0 0.29 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KPA35878.1 - 0.0011 18.9 0.2 0.21 11.5 0.0 2.6 2 0 0 2 2 2 1 NTPase AAA_24 PF13479.6 KPA35878.1 - 0.0011 18.8 0.5 3.7 7.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.6 KPA35878.1 - 0.0011 19.4 1.3 0.16 12.4 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPA35878.1 - 0.0022 18.5 10.4 0.14 12.7 0.0 4.3 4 1 0 4 4 2 2 AAA domain Mg_chelatase PF01078.21 KPA35878.1 - 0.0025 17.3 0.0 1.9 7.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KPA35878.1 - 0.0025 18.2 0.3 4.4 7.7 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Torsin PF06309.11 KPA35878.1 - 0.004 17.2 0.1 17 5.6 0.0 3.6 3 0 0 3 3 3 0 Torsin AAA_33 PF13671.6 KPA35878.1 - 0.0063 16.7 4.2 1.9 8.6 0.0 3.5 5 0 0 5 5 3 2 AAA domain IstB_IS21 PF01695.17 KPA35878.1 - 0.0099 15.6 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KPA35878.1 - 0.016 15.0 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 KPA35878.1 - 0.017 15.4 5.1 0.58 10.4 0.1 3.6 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KPA35878.1 - 0.043 13.3 0.1 18 4.8 0.0 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region Colicin_Pyocin PF01320.18 KPA35878.1 - 0.069 13.3 0.3 0.75 10.0 0.1 2.6 2 0 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein AAA_11 PF13086.6 KPA35878.1 - 0.58 9.9 12.7 1.1 9.0 0.0 3.8 4 0 0 4 4 4 0 AAA domain F-box_4 PF15966.5 KPA35879.1 - 0.049 13.5 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 F-box zf-HC2 PF13490.6 KPA35879.1 - 8.1 6.8 5.9 3.6 7.9 0.1 2.7 3 0 0 3 3 3 0 Putative zinc-finger Ank_2 PF12796.7 KPA35880.1 - 1.1e-11 45.1 0.1 1.7e-06 28.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA35880.1 - 7.5e-10 38.2 0.1 0.24 12.1 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat NACHT PF05729.12 KPA35880.1 - 1.5e-09 38.0 0.0 5.9e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KPA35880.1 - 1.9e-08 34.9 0.0 6.1e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Ank_4 PF13637.6 KPA35880.1 - 4.2e-08 33.6 2.2 0.047 14.3 0.0 5.1 3 2 2 5 5 5 3 Ankyrin repeats (many copies) NACHT_N PF17100.5 KPA35880.1 - 3.2e-07 30.4 0.3 8.2e-07 29.1 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_5 PF13857.6 KPA35880.1 - 2.1e-06 27.9 0.4 0.0031 17.8 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KPA35880.1 - 2.2e-05 24.7 3.3 0.089 13.3 0.1 4.8 5 0 0 5 5 5 1 Ankyrin repeat AAA_22 PF13401.6 KPA35880.1 - 0.00029 21.1 0.0 0.0041 17.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPA35880.1 - 0.021 15.4 1.1 2.9 8.4 0.0 3.7 3 1 0 3 3 3 0 AAA domain Ank PF00023.30 KPA35881.1 - 2.8e-08 33.8 0.0 0.42 11.1 0.1 4.5 3 1 1 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KPA35881.1 - 2.8e-08 33.4 0.2 0.031 14.8 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KPA35881.1 - 2e-07 31.5 0.0 0.0045 17.5 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA35881.1 - 3.6e-07 30.6 0.0 0.46 11.1 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA35881.1 - 0.0014 18.9 0.1 13 6.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) zf-Sec23_Sec24 PF04810.15 KPA35882.1 - 0.16 12.1 1.9 0.82 9.8 0.3 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Glyco_hydro_20 PF00728.22 KPA35883.1 - 1.6e-42 146.2 0.3 2.7e-41 142.2 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain ANAPC4 PF12896.7 KPA35883.1 - 0.068 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Sugar_tr PF00083.24 KPA35884.1 - 4.8e-115 385.0 15.2 8.2e-115 384.2 15.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA35884.1 - 1.8e-20 73.2 47.8 6.6e-11 41.7 23.4 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KPA35885.1 - 0.00029 20.0 0.0 0.0012 18.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain HET PF06985.11 KPA35886.1 - 3e-26 92.5 0.0 5.3e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.6 KPA35886.1 - 2.8e-14 51.8 0.1 3.6e-05 23.8 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KPA35886.1 - 9.9e-13 48.3 0.1 4e-10 40.0 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA35886.1 - 2.8e-11 43.9 0.0 4.7e-09 36.7 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KPA35886.1 - 9.2e-11 41.7 0.3 0.00081 19.7 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KPA35886.1 - 8.1e-09 35.6 0.5 4.3e-06 26.9 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Rrf2 PF02082.20 KPA35887.1 - 0.051 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator adh_short_C2 PF13561.6 KPA35888.1 - 9.2e-29 100.7 0.0 1.8e-27 96.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA35888.1 - 3.4e-21 75.6 0.0 4.2e-20 72.0 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA35888.1 - 2.5e-05 24.2 0.0 4.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Enoyl_reductase PF12241.8 KPA35888.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Epimerase PF01370.21 KPA35888.1 - 0.032 13.7 0.0 0.22 11.0 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 KPA35889.1 - 2.8e-19 69.5 0.0 4.4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA35889.1 - 1.1e-13 51.6 0.0 4.8e-13 49.6 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA35889.1 - 6.9e-13 49.1 0.0 1.6e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA35889.1 - 1.2e-09 38.1 0.0 1.6e-08 34.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA35889.1 - 2e-07 31.7 0.0 1.2e-06 29.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA35889.1 - 6.7e-06 25.6 0.0 5.5e-05 22.6 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KPA35889.1 - 6.9e-05 22.6 0.0 0.00017 21.4 0.0 1.6 2 0 0 2 2 2 1 Lysine methyltransferase MTS PF05175.14 KPA35889.1 - 0.0029 17.2 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KPA35889.1 - 0.0099 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KPA35889.1 - 0.015 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 KPA35889.1 - 0.023 14.0 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 KPA35889.1 - 0.031 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) NNMT_PNMT_TEMT PF01234.17 KPA35889.1 - 0.07 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_2 PF00891.18 KPA35889.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain adh_short PF00106.25 KPA35891.1 - 1.3e-28 99.8 0.0 7.3e-23 81.1 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA35891.1 - 7.2e-14 51.9 0.0 2e-11 43.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA35891.1 - 3.4e-08 33.6 0.4 7.9e-08 32.4 0.3 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KPA35891.1 - 0.0073 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KPA35891.1 - 0.022 14.1 0.5 0.66 9.3 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KPA35891.1 - 0.059 13.4 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.15 KPA35891.1 - 0.073 12.9 0.1 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus Polysacc_synt_2 PF02719.15 KPA35891.1 - 0.17 11.0 0.2 0.31 10.1 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Peptidase_S8 PF00082.22 KPA35892.1 - 6.6e-44 150.3 3.8 1e-43 149.8 3.8 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KPA35892.1 - 2.3e-13 50.8 0.0 6.4e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 KPA35892.1 - 2.8e-07 30.5 0.1 8.2e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 PA domain FlgD_ig PF13860.6 KPA35892.1 - 0.0025 17.6 1.8 0.0055 16.5 0.2 2.4 2 0 0 2 2 2 1 FlgD Ig-like domain p450 PF00067.22 KPA35893.1 - 4.8e-84 282.7 0.0 5.7e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BAH PF01426.18 KPA35897.1 - 2.4e-07 30.6 0.0 4.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 BAH domain GATA PF00320.27 KPA35899.1 - 1.1e-13 50.5 2.1 3.3e-13 49.0 2.1 1.9 1 0 0 1 1 1 1 GATA zinc finger zf-C2H2_3 PF13878.6 KPA35899.1 - 0.13 12.1 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO OPT PF03169.15 KPA35900.1 - 2.9e-79 267.4 20.1 3.5e-79 267.1 20.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OrsD PF12013.8 KPA35901.1 - 7.5e-14 52.1 0.4 1.7e-13 51.0 0.4 1.6 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D DEAD PF00270.29 KPA35901.1 - 1.5e-09 37.9 0.0 3.2e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AF-4 PF05110.13 KPA35901.1 - 0.23 9.5 2.6 0.45 8.5 2.6 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Acyl_transf_3 PF01757.22 KPA35903.1 - 1.3e-32 113.3 31.8 1.5e-32 113.1 31.8 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.15 KPA35904.1 - 2e-12 47.6 0.0 4.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KPA35904.1 - 0.067 12.6 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Fungal_trans PF04082.18 KPA35905.1 - 5.2e-24 84.7 0.0 1e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA35905.1 - 2.1e-07 30.9 12.9 2.1e-07 30.9 12.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NRBF2 PF08961.10 KPA35905.1 - 0.12 12.0 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Pkinase_Tyr PF07714.17 KPA35907.1 - 4.4e-08 32.7 0.1 6.1e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KPA35907.1 - 9.9e-08 31.7 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain T2SSS_2 PF16549.5 KPA35907.1 - 0.0097 15.9 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS) pilotin, S protein DUF3723 PF12520.8 KPA35908.1 - 1.8e-48 165.5 0.0 2.5e-25 89.1 0.1 3.0 2 1 1 3 3 3 3 Protein of unknown function (DUF3723) Amidase PF01425.21 KPA35909.1 - 8.7e-34 117.3 0.2 3.9e-30 105.2 0.1 2.2 2 0 0 2 2 2 2 Amidase PSRT PF07636.11 KPA35909.1 - 0.1 12.3 0.2 0.27 11.0 0.2 1.7 1 0 0 1 1 1 0 PSRT DUF2534 PF10749.9 KPA35911.1 - 0.06 13.5 0.5 0.06 13.5 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2534) MscS_TM PF12794.7 KPA35911.1 - 3.3 6.5 16.6 0.055 12.3 1.3 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 FA_desaturase PF00487.24 KPA35911.1 - 5.9 6.6 8.5 9 6.0 8.5 1.4 1 1 0 1 1 1 0 Fatty acid desaturase NAD_binding_10 PF13460.6 KPA35912.1 - 2.3e-21 76.5 0.0 2.8e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPA35912.1 - 4.5e-07 29.7 0.0 6.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KPA35912.1 - 5.5e-07 29.3 0.0 7.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PAC2 PF09754.9 KPA35912.1 - 0.13 12.2 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 PAC2 family FAD_binding_3 PF01494.19 KPA35913.1 - 5.8e-29 101.4 0.0 7.9e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA35913.1 - 1.5e-06 28.1 3.2 0.01 15.4 2.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA35913.1 - 5.3e-06 25.9 0.2 0.00029 20.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA35913.1 - 6.6e-06 26.3 0.5 2e-05 24.7 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPA35913.1 - 1.8e-05 24.0 1.4 4.1e-05 22.8 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KPA35913.1 - 0.00054 18.9 1.6 0.0025 16.8 0.7 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 KPA35913.1 - 0.00088 19.8 0.3 0.0056 17.2 0.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA35913.1 - 0.001 17.9 1.6 0.0019 17.0 0.7 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KPA35913.1 - 0.006 16.0 0.7 0.011 15.1 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPA35913.1 - 0.007 15.6 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KPA35913.1 - 0.013 14.6 0.4 0.019 14.1 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPA35913.1 - 0.015 14.6 2.0 0.026 13.8 2.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KPA35913.1 - 0.03 13.9 0.3 0.068 12.8 0.3 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KPA35913.1 - 0.1 11.9 0.2 0.22 10.8 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain T7SS_ESX_EspC PF10824.8 KPA35913.1 - 0.69 10.4 3.9 0.87 10.1 2.2 2.0 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm UbiA PF01040.18 KPA35914.1 - 8.9e-44 149.7 13.8 1.3e-43 149.1 13.8 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Oxidored_q3 PF00499.20 KPA35914.1 - 0.023 14.4 1.3 0.023 14.4 1.3 2.3 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Cupin_2 PF07883.11 KPA35915.1 - 0.018 14.7 0.2 0.04 13.6 0.2 1.5 1 0 0 1 1 1 0 Cupin domain FAD_binding_3 PF01494.19 KPA35916.1 - 2.1e-66 224.6 0.1 6.6e-66 222.9 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KPA35916.1 - 1.4e-05 24.4 0.7 2.5e-05 23.5 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA35916.1 - 2.4e-05 24.1 1.0 0.00098 18.8 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA35916.1 - 4.1e-05 22.9 0.0 6.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA35916.1 - 0.00015 21.9 0.2 0.00035 20.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KPA35916.1 - 0.0002 20.6 0.2 0.0003 20.0 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KPA35916.1 - 0.00025 20.4 0.1 0.00041 19.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KPA35916.1 - 0.00054 19.3 0.1 0.00093 18.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KPA35916.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KPA35916.1 - 0.0024 16.7 0.1 0.0036 16.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KPA35916.1 - 0.0068 15.8 0.4 0.011 15.1 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPA35916.1 - 0.057 12.5 0.2 0.086 11.9 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FUSC_2 PF13515.6 KPA35918.1 - 1.8e-21 76.6 4.1 1.8e-21 76.6 4.1 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KPA35918.1 - 0.00016 20.7 2.1 0.00016 20.7 2.1 3.7 4 1 0 4 4 4 2 Aluminium activated malate transporter Phage_holin_Dp1 PF16938.5 KPA35918.1 - 0.0068 16.6 1.4 0.025 14.8 0.3 2.5 2 0 0 2 2 2 1 Putative phage holin Dp-1 FUSC PF04632.12 KPA35918.1 - 0.014 13.9 8.7 0.018 13.6 0.4 3.4 4 1 0 4 4 4 0 Fusaric acid resistance protein family Phage_holin_3_1 PF05106.12 KPA35918.1 - 0.15 12.5 1.8 2 8.9 1.4 2.9 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) CPP1-like PF11833.8 KPA35918.1 - 2.7 7.6 8.7 0.28 10.8 1.8 2.7 3 1 1 4 4 4 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Aegerolysin PF06355.13 KPA35920.1 - 1.6e-47 160.8 1.3 1.8e-47 160.7 1.3 1.0 1 0 0 1 1 1 1 Aegerolysin MARVEL PF01284.23 KPA35921.1 - 0.00016 21.7 17.4 0.00025 21.1 17.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF3270 PF11674.8 KPA35921.1 - 0.38 11.0 1.7 3.3 7.9 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3270) MFS_1 PF07690.16 KPA35922.1 - 6e-20 71.5 18.7 1.4e-19 70.3 9.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA35922.1 - 2.8e-06 26.5 9.5 2.8e-06 26.5 9.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3750 PF12570.8 KPA35923.1 - 0.074 13.8 0.5 3.1 8.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3750) HET PF06985.11 KPA35924.1 - 1e-31 110.3 0.6 1.8e-31 109.5 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Macro_2 PF14519.6 KPA35925.1 - 0.0012 18.2 0.0 0.0024 17.3 0.0 1.4 1 1 0 1 1 1 1 Macro-like domain zf-C2H2 PF00096.26 KPA35926.1 - 2.1e-06 27.9 11.0 0.015 15.7 1.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA35926.1 - 5.5e-05 23.7 10.3 0.18 12.7 1.1 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KPA35926.1 - 0.06 13.1 0.1 0.06 13.1 0.1 3.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain OrsD PF12013.8 KPA35926.1 - 0.2 12.1 9.8 0.15 12.5 6.8 2.4 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_jaz PF12171.8 KPA35926.1 - 0.2 12.0 6.4 1.7 9.0 2.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KPA35926.1 - 0.98 9.1 3.7 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 KPA35926.1 - 1.1 9.2 5.6 33 4.4 0.3 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KPA35926.1 - 1.2 9.6 7.5 1.2 9.5 1.2 2.7 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 KPA35926.1 - 4.1 8.1 9.6 17 6.1 0.2 3.7 3 1 1 4 4 4 0 FOXP coiled-coil domain BCS1_N PF08740.11 KPA35928.1 - 2e-19 70.3 0.0 2.5e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AA_permease_2 PF13520.6 KPA35930.1 - 8.6e-50 169.8 49.8 1.1e-49 169.5 49.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA35930.1 - 1.9e-24 86.1 40.9 2.5e-24 85.7 40.9 1.1 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.6 KPA35930.1 - 9.6 6.6 9.7 0.25 11.7 1.0 2.6 2 1 0 2 2 2 0 YlaH-like protein Acetyltransf_7 PF13508.7 KPA35932.1 - 1.3e-09 38.4 0.0 4.8e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA35932.1 - 7.9e-09 35.8 0.0 3.3e-08 33.8 0.0 1.7 1 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA35932.1 - 9.3e-07 28.8 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA35932.1 - 0.00049 20.2 0.0 0.0014 18.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA35932.1 - 0.009 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF4123 PF13503.6 KPA35932.1 - 0.012 16.0 0.1 0.021 15.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) HET PF06985.11 KPA35934.1 - 9.6e-20 71.4 0.0 1.6e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KPA35934.1 - 1.7e-14 54.2 0.9 5.6e-08 33.3 0.1 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA35934.1 - 3.5e-13 49.5 1.6 2e-08 34.3 0.2 4.6 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPA35934.1 - 5e-13 49.3 1.5 1.1e-05 25.8 0.1 3.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA35934.1 - 1.6e-09 37.2 1.4 0.0004 20.6 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KPA35934.1 - 3e-06 27.4 1.9 0.00083 19.7 0.1 4.0 4 1 0 4 4 4 1 Ankyrin repeat Acetyltransf_2 PF00797.17 KPA35935.1 - 3.8e-43 148.0 0.1 6.2e-43 147.3 0.1 1.3 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 KPA35935.1 - 0.0031 17.9 0.0 0.025 15.0 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF2009 PF09418.10 KPA35935.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Glyco_tranf_2_3 PF13641.6 KPA35936.1 - 6.5e-24 85.1 0.0 8.9e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPA35936.1 - 6.3e-08 32.6 0.0 1.5e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KPA35936.1 - 5.3e-07 29.3 0.0 1.2e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 BPL_N PF09825.9 KPA35940.1 - 6.8e-08 32.0 0.4 6.5e-05 22.2 0.4 2.2 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal Zn_clus PF00172.18 KPA35940.1 - 1.9e-06 27.9 8.6 3.4e-06 27.1 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HCIx2C PF10782.9 KPA35941.1 - 0.27 11.2 1.8 0.86 9.6 1.8 1.9 1 0 0 1 1 1 0 Zinc-finger EVE PF01878.18 KPA35942.1 - 2.2e-46 157.5 0.0 2.2e-46 157.5 0.0 1.6 2 0 0 2 2 2 1 EVE domain Presenilin PF01080.17 KPA35942.1 - 2 7.1 4.3 2.5 6.8 4.3 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KPA35942.1 - 5.7 5.5 5.3 5.6 5.5 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ADH_N PF08240.12 KPA35944.1 - 1.6e-11 44.0 0.3 4.7e-11 42.5 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ROK PF00480.20 KPA35944.1 - 1.4e-07 31.3 0.0 9.4e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 ROK family Glu_dehyd_C PF16912.5 KPA35944.1 - 0.0004 19.9 0.0 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ApbA PF02558.16 KPA35944.1 - 0.0007 19.3 0.1 0.0017 18.0 0.1 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KPA35944.1 - 0.001 19.1 0.6 0.0023 18.0 0.2 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 KPA35944.1 - 0.0017 17.6 0.1 0.0034 16.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 KPA35944.1 - 0.0069 16.4 0.5 0.023 14.7 0.5 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase T2SS_PulS_OutS PF09691.10 KPA35944.1 - 0.031 14.5 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 Type II secretion system pilotin lipoprotein (PulS_OutS) GCHY-1 PF02649.14 KPA35944.1 - 0.045 13.2 0.3 0.079 12.5 0.3 1.4 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 DUF5538 PF17692.1 KPA35944.1 - 0.065 13.3 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5538) AlaDh_PNT_C PF01262.21 KPA35944.1 - 0.13 11.5 3.3 0.31 10.3 1.4 2.3 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PMM PF03332.13 KPA35945.1 - 1.3e-10 41.4 0.0 1.7e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KPA35945.1 - 9e-06 25.6 0.0 1.2e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KPA35945.1 - 0.18 11.3 0.0 0.58 9.6 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase adh_short_C2 PF13561.6 KPA35946.1 - 1.8e-57 194.6 1.5 2.3e-57 194.3 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA35946.1 - 5e-50 169.7 2.6 6e-50 169.4 2.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA35946.1 - 4.6e-05 23.4 1.2 0.00012 22.0 1.2 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KPA35946.1 - 0.0004 20.3 0.3 0.00064 19.7 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KPA35946.1 - 0.064 13.5 0.1 0.094 13.0 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Aldedh PF00171.22 KPA35947.1 - 4.5e-150 500.2 0.0 6e-150 499.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Amidase PF01425.21 KPA35948.1 - 8.4e-70 236.0 0.0 1.3e-69 235.3 0.0 1.3 1 0 0 1 1 1 1 Amidase PARP PF00644.20 KPA35948.1 - 1.1e-07 31.7 0.0 1.8e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain MOSC PF03473.17 KPA35949.1 - 1.7e-20 73.4 0.0 2.2e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 MOSC domain Oxidored_FMN PF00724.20 KPA35950.1 - 4.2e-55 187.4 0.0 5.5e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.25 KPA35951.1 - 5.6e-19 68.4 0.0 6.2e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA35951.1 - 6.5e-07 29.2 0.0 1.3e-06 28.1 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA35951.1 - 2.1e-05 24.5 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KPA35952.1 - 2.1e-10 40.7 0.0 3.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA35952.1 - 0.00029 20.7 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF4083 PF13314.6 KPA35953.1 - 0.24 11.4 0.3 0.55 10.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) adh_short PF00106.25 KPA35954.1 - 2.3e-40 138.1 0.3 3.3e-40 137.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA35954.1 - 5e-35 121.2 0.0 8.2e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA35954.1 - 2.5e-12 47.1 0.1 4.5e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KPA35954.1 - 0.21 11.5 2.1 0.35 10.7 2.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KPA35955.1 - 3.2e-12 46.6 0.0 5.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA35955.1 - 0.00015 21.6 0.0 0.002 18.0 0.0 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPA35955.1 - 0.0012 19.9 0.0 0.0027 18.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPA35955.1 - 0.008 15.7 0.0 0.69 9.4 0.0 2.4 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus XdhC_C PF13478.6 KPA35955.1 - 0.017 15.7 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain E1-N PF14463.6 KPA35955.1 - 0.17 11.7 1.6 0.32 10.8 1.6 1.4 1 1 0 1 1 1 0 E1 N-terminal domain p450 PF00067.22 KPA35956.1 - 3.3e-36 125.0 0.0 6.2e-34 117.5 0.0 2.8 1 1 2 3 3 3 2 Cytochrome P450 TRI9 PF08195.11 KPA35956.1 - 0.14 12.1 2.3 0.92 9.5 0.6 2.4 1 1 1 2 2 2 0 TRI9 protein MRP-S26 PF14943.6 KPA35957.1 - 3.9 7.3 23.7 6 6.8 23.7 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF2868 PF11067.8 KPA35957.1 - 5.5 6.4 10.5 0.58 9.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) SMP_LBD PF17047.5 KPA35958.1 - 7.5e-23 80.9 0.1 1.2e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KPA35958.1 - 2.9e-15 56.4 0.0 1.4e-11 44.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KPA35958.1 - 0.15 12.0 0.0 0.79 9.6 0.0 2.0 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 Fungal_trans PF04082.18 KPA35959.1 - 2.7e-13 49.6 0.0 6.7e-13 48.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain HpcH_HpaI PF03328.14 KPA35959.1 - 3.8e-12 45.8 0.0 5.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KPA35959.1 - 0.1 11.5 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Aminotran_1_2 PF00155.21 KPA35960.1 - 2.3e-58 198.1 0.0 2.6e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF296 PF03479.15 KPA35960.1 - 0.1 13.0 0.3 0.21 12.0 0.3 1.5 1 0 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain PHO4 PF01384.20 KPA35963.1 - 8e-101 337.5 16.8 9.2e-101 337.3 16.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF3237 PF11578.8 KPA35964.1 - 2.5e-29 102.1 0.0 2.7e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Abhydrolase_1 PF00561.20 KPA35965.1 - 1.4e-13 51.1 0.0 2.5e-13 50.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA35965.1 - 1.6e-11 43.9 0.0 5.2e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA35965.1 - 6.8e-09 36.7 0.0 9.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KPA35965.1 - 0.00018 21.2 0.5 0.0078 15.9 0.5 2.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 KPA35965.1 - 0.0012 18.8 0.1 0.012 15.5 0.1 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KPA35965.1 - 0.002 17.8 0.1 0.0061 16.2 0.1 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KPA35965.1 - 0.016 14.8 0.0 0.046 13.3 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KPA35965.1 - 0.022 14.2 0.0 0.66 9.4 0.0 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 KPA35965.1 - 0.025 14.3 0.0 0.064 13.0 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 KPA35965.1 - 0.046 13.8 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PhoPQ_related PF10142.9 KPA35965.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_4 PF08386.10 KPA35965.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein SmpB PF01668.18 KPA35965.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 SmpB protein bZIP_1 PF00170.21 KPA35966.1 - 4e-08 33.2 3.4 7.5e-08 32.4 3.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KPA35966.1 - 0.0025 18.3 1.8 0.0057 17.2 1.8 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KPA35966.1 - 0.018 15.1 6.3 0.042 13.9 6.3 1.5 1 0 0 1 1 1 0 Basic region leucine zipper FAD_binding_3 PF01494.19 KPA35970.1 - 6.1e-18 65.2 0.2 6.6e-14 51.9 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPA35970.1 - 9.2e-14 51.8 0.2 2.2e-08 34.1 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA35970.1 - 8.1e-08 31.8 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA35970.1 - 4.1e-07 30.1 0.1 1.2e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPA35970.1 - 7.3e-05 22.0 0.0 0.00015 21.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KPA35970.1 - 0.00011 22.7 0.1 0.0008 19.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPA35970.1 - 0.00051 19.0 0.3 0.02 13.8 0.0 2.7 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 KPA35970.1 - 0.00083 18.2 0.3 0.0074 15.0 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KPA35970.1 - 0.003 16.9 0.0 0.01 15.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPA35970.1 - 0.0056 16.0 0.1 1 8.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 KPA35970.1 - 0.0061 15.8 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KPA35970.1 - 0.01 14.9 1.3 0.54 9.3 0.1 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KPA35970.1 - 0.1 11.9 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KPA35970.1 - 0.12 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_S15 PF02129.18 KPA35971.1 - 1.7e-44 152.4 1.4 2e-41 142.4 0.2 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KPA35971.1 - 3.6e-31 108.9 0.0 5.2e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KPA35971.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPA35971.1 - 0.031 13.7 0.2 0.075 12.5 0.2 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family PhyH PF05721.13 KPA35972.1 - 2.7e-06 27.8 0.1 1.2e-05 25.6 0.1 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KPA35972.1 - 0.00029 19.7 0.2 0.36 9.6 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 KPA35972.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KPA35972.1 - 0.14 13.0 0.0 0.31 12.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KPA35973.1 - 1.8e-22 80.0 0.0 3e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA35973.1 - 1.1e-07 31.5 0.0 2.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1911 PF08929.10 KPA35973.1 - 0.069 14.0 0.0 0.47 11.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) Fringe PF02434.16 KPA35976.1 - 9.8e-07 28.5 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Fringe-like PAN_1 PF00024.26 KPA35976.1 - 0.0023 17.8 0.2 0.0047 16.9 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KPA35976.1 - 0.036 14.0 3.0 0.043 13.7 1.2 2.0 2 0 0 2 2 2 0 PAN domain PAN_3 PF08277.12 KPA35976.1 - 0.14 12.0 0.1 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 PAN-like domain MFS_1 PF07690.16 KPA35977.1 - 8.5e-22 77.6 19.8 9.6e-22 77.4 19.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_2 PF12796.7 KPA35978.1 - 1.3e-07 32.1 0.0 0.011 16.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA35978.1 - 2.9e-06 27.7 0.0 0.014 15.9 0.0 3.9 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA35978.1 - 0.00018 21.7 0.1 0.0094 16.2 0.0 2.9 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA35978.1 - 0.015 15.7 0.1 39 5.3 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.30 KPA35978.1 - 0.019 15.4 0.5 9.5 6.9 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 KPA35979.1 - 1e-10 42.0 0.0 3.2e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA35979.1 - 4.4e-06 26.9 0.0 0.082 13.3 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KPA35979.1 - 0.00021 21.6 0.0 5.7 7.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KPA35979.1 - 0.0013 19.0 0.1 17 6.4 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KPA35979.1 - 0.004 17.7 0.1 14 6.4 0.1 3.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF4566 PF15130.6 KPA35979.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) Peptidase_C2 PF00648.21 KPA35980.1 - 3.2e-57 193.8 0.5 3e-56 190.6 0.5 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease DLH PF01738.18 KPA35981.1 - 1.6e-05 24.6 0.0 0.0036 16.9 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF1100 PF06500.11 KPA35981.1 - 2.4e-05 23.3 0.0 3.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 KPA35981.1 - 0.00029 20.4 0.0 0.00082 18.9 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KPA35981.1 - 0.00064 19.4 0.1 0.089 12.4 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KPA35981.1 - 0.0018 17.9 0.0 0.0061 16.2 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KPA35981.1 - 0.0033 16.7 0.0 0.016 14.5 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KPA35981.1 - 0.0066 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KPA35981.1 - 0.0092 16.6 0.0 0.036 14.6 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KPA35981.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.8 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 KPA35981.1 - 0.039 12.6 0.0 0.075 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 KPA35981.1 - 0.045 13.9 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 KPA35981.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Zn_clus PF00172.18 KPA35982.1 - 1.7e-09 37.6 9.0 3.9e-09 36.5 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA35982.1 - 9.1e-08 31.3 2.4 1.9e-07 30.2 1.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Takusan PF04822.13 KPA35983.1 - 0.008 16.0 1.6 0.012 15.5 0.5 1.8 1 1 1 2 2 2 1 Takusan bZIP_1 PF00170.21 KPA35983.1 - 0.0085 16.2 7.0 0.013 15.6 7.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor PV-1 PF06637.11 KPA35983.1 - 0.0095 14.8 0.3 0.012 14.4 0.3 1.1 1 0 0 1 1 1 1 PV-1 protein (PLVAP) ABC_tran_Xtn PF12848.7 KPA35983.1 - 0.011 15.7 2.6 0.017 15.2 2.6 1.2 1 0 0 1 1 1 0 ABC transporter RP-C_C PF11800.8 KPA35983.1 - 0.041 14.0 1.5 0.057 13.5 1.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region TMF_TATA_bd PF12325.8 KPA35983.1 - 0.13 12.5 3.7 0.19 11.9 3.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HrpJ PF07201.11 KPA35983.1 - 0.28 11.5 4.2 0.4 11.0 4.2 1.1 1 0 0 1 1 1 0 HrpJ-like domain DivIC PF04977.15 KPA35983.1 - 2.6 7.9 6.3 9.5 6.1 0.3 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF5601 PF18151.1 KPA35984.1 - 0.068 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) SAS4 PF15460.6 KPA35984.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.4 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 COesterase PF00135.28 KPA35985.1 - 4.6e-60 204.0 0.0 6e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA35985.1 - 2.2e-06 27.7 0.2 2.7e-05 24.2 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Zn_clus PF00172.18 KPA35986.1 - 0.00023 21.2 14.0 0.00046 20.3 14.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA35986.1 - 0.00031 19.9 0.0 0.00051 19.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SAPS PF04499.15 KPA35987.1 - 0.16 10.7 0.8 0.16 10.7 0.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 KPA35988.1 - 0.039 13.3 4.5 0.053 12.9 4.5 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 KPA35988.1 - 0.66 8.4 3.7 0.91 8.0 3.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 OrsD PF12013.8 KPA35989.1 - 1.2e-09 38.6 1.9 2.3e-09 37.7 1.9 1.4 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Glu_synthase PF01645.17 KPA35989.1 - 0.21 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase Beta_helix PF13229.6 KPA35990.1 - 4.8e-15 55.8 36.8 7.9e-10 38.8 13.4 2.5 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 KPA35990.1 - 3.8e-08 32.9 19.2 0.00012 21.4 6.4 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) PAP2 PF01569.21 KPA35991.1 - 9.5e-26 90.2 3.9 9.5e-26 90.2 3.9 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KPA35991.1 - 2.1 9.0 8.4 0.16 12.5 2.4 2.3 2 1 0 2 2 2 0 PAP2 superfamily C-terminal bZIP_1 PF00170.21 KPA35993.1 - 1.6e-10 41.0 2.5 3.6e-10 39.8 2.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPA35993.1 - 2.8e-07 30.5 2.9 6.2e-07 29.4 2.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper KAR9 PF08580.10 KPA35993.1 - 0.00023 19.9 0.2 0.00041 19.0 0.2 1.3 1 0 0 1 1 1 1 Yeast cortical protein KAR9 bZIP_Maf PF03131.17 KPA35993.1 - 0.0061 17.0 2.2 0.014 15.9 2.2 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF4618 PF15397.6 KPA35993.1 - 0.0092 15.4 0.5 0.013 14.9 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) ATP-synt_ab PF00006.25 KPA35994.1 - 1.2e-62 211.3 0.0 1.9e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KPA35994.1 - 4.2e-23 81.7 2.5 7.4e-23 80.9 0.9 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 KPA35994.1 - 0.014 15.3 0.3 0.033 14.1 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 KPA35994.1 - 0.02 14.1 0.2 0.082 12.1 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 KPA35994.1 - 0.023 15.1 0.0 0.54 10.7 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KPA35994.1 - 0.025 13.9 0.1 0.049 13.0 0.1 1.5 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 KPA35994.1 - 0.035 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KPA35994.1 - 0.049 13.5 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KPA35994.1 - 0.071 13.5 0.9 0.48 10.8 0.2 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KPA35994.1 - 0.086 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RnfC_N PF13375.6 KPA35994.1 - 0.098 12.6 0.2 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Pox_A32 PF04665.12 KPA35994.1 - 0.1 12.0 0.6 0.66 9.4 0.2 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_16 PF13191.6 KPA35994.1 - 0.14 12.6 0.5 0.4 11.0 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 KPA35994.1 - 0.14 12.2 0.1 0.43 10.6 0.1 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 KPA35994.1 - 0.31 9.9 0.9 0.47 9.3 0.1 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Pkinase PF00069.25 KPA35995.1 - 1.2e-43 149.4 0.0 3.8e-43 147.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA35995.1 - 4e-22 78.7 0.0 2.9e-21 75.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPA35995.1 - 0.00028 20.3 0.1 0.00063 19.2 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KPA35995.1 - 0.0017 18.0 0.3 0.0058 16.3 0.3 1.7 1 1 0 1 1 1 1 RIO1 family WaaY PF06176.11 KPA35995.1 - 0.017 14.7 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kinase-like PF14531.6 KPA35995.1 - 0.13 11.5 3.3 0.084 12.2 0.5 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 KPA35996.1 - 1.1e-13 51.2 0.0 1.7e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KPA35996.1 - 1.3e-05 25.2 0.2 2.4e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KPA35996.1 - 0.0033 16.8 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase peroxidase PF00141.23 KPA35997.1 - 6.3e-83 278.0 0.0 1.6e-45 155.6 0.0 2.3 2 0 0 2 2 2 2 Peroxidase Ank_2 PF12796.7 KPA35998.1 - 1.5e-110 362.0 13.5 5.9e-20 71.6 0.0 5.9 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA35998.1 - 2.4e-98 321.3 10.9 1.4e-12 47.9 0.0 10.1 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 KPA35998.1 - 1.5e-75 246.6 11.2 1.1e-06 28.8 0.0 12.1 12 0 0 12 12 12 12 Ankyrin repeat Ank_5 PF13857.6 KPA35998.1 - 2.3e-74 244.5 0.2 1.8e-09 37.7 0.0 7.4 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA35998.1 - 5.8e-69 219.8 0.0 0.00011 22.3 0.0 12.2 12 0 0 12 12 12 11 Ankyrin repeat SpoU_sub_bind PF08032.12 KPA35998.1 - 5.7e-06 26.5 1.7 93 3.4 0.0 8.3 5 3 4 9 9 9 0 RNA 2'-O ribose methyltransferase substrate binding VWA_3_C PF18571.1 KPA35998.1 - 2.8e-05 23.9 38.4 2.4 8.1 0.1 11.4 12 0 0 12 12 12 1 von Willebrand factor type A C-terminal domain Nse4-Nse3_bdg PF15412.6 KPA35998.1 - 0.00012 22.1 1.0 20 5.4 0.0 5.4 6 0 0 6 6 6 0 Binding domain of Nse4/EID3 to Nse3-MAGE CTD PF12815.7 KPA35998.1 - 0.0074 16.8 2.5 3.1 8.4 0.0 4.3 3 2 1 4 4 4 1 Spt5 C-terminal nonapeptide repeat binding Spt4 INTS5_C PF14838.6 KPA35998.1 - 0.0085 14.8 0.0 7.2 5.1 0.0 3.4 1 1 2 3 3 3 2 Integrator complex subunit 5 C-terminus DUF3734 PF12536.8 KPA35998.1 - 0.014 15.7 4.3 6.3 7.2 0.1 4.3 2 2 1 4 4 4 0 Patatin phospholipase DoxD PF04173.13 KPA35998.1 - 0.018 14.9 0.0 23 4.8 0.0 5.0 6 3 0 7 7 7 0 TQO small subunit DoxD GATase_7 PF13537.6 KPA35998.1 - 0.14 12.0 0.0 2.2e+02 1.7 0.0 4.5 4 1 0 5 5 5 0 Glutamine amidotransferase domain P19Arf_N PF07392.12 KPA35998.1 - 0.78 10.2 6.5 1.3e+02 3.1 0.0 6.3 8 0 0 8 8 8 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus DUF3070 PF11270.8 KPA35998.1 - 1.4 9.2 3.5 1.2e+02 3.0 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3070) GARS_A PF01071.19 KPA35999.1 - 4.1e-72 242.1 0.0 5.4e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KPA35999.1 - 5.5e-25 88.0 0.0 2.5e-21 76.3 0.0 2.4 1 1 1 2 2 2 2 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KPA35999.1 - 2.7e-16 59.6 0.1 5.9e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_3 PF02655.14 KPA35999.1 - 0.033 14.3 0.0 0.18 11.8 0.0 2.2 2 1 0 2 2 2 0 ATP-grasp domain p450 PF00067.22 KPA36000.1 - 4.9e-29 101.4 0.0 1e-28 100.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KPA36001.1 - 3.9e-12 45.7 0.3 5e-12 45.3 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KPA36002.1 - 9.8e-57 192.2 0.8 1.1e-56 192.0 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA36002.1 - 4.9e-39 133.8 0.5 6.2e-39 133.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA36002.1 - 3.4e-12 46.6 0.1 4.9e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Glyco_hydro_1 PF00232.18 KPA36002.1 - 0.0091 14.4 0.1 0.012 14.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Methyltransf_31 PF13847.6 KPA36002.1 - 0.036 13.9 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Spheroidin PF05541.12 KPA36002.1 - 0.072 10.9 0.2 0.091 10.6 0.2 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein ADH_N PF08240.12 KPA36003.1 - 0.0061 16.4 0.0 0.007 16.2 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAP PF02037.27 KPA36003.1 - 0.034 13.9 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 SAP domain Metallophos PF00149.28 KPA36004.1 - 1.1e-06 29.4 0.1 1.1e-06 29.3 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPA36004.1 - 0.019 15.2 0.0 0.02 15.1 0.0 1.0 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain F-box-like PF12937.7 KPA36005.1 - 4.8e-07 29.6 4.6 1.4e-05 24.9 1.1 2.7 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KPA36005.1 - 3.3 7.7 7.8 0.73 9.8 0.9 2.9 2 2 0 2 2 2 0 F-box domain FSH1 PF03959.13 KPA36006.1 - 1.7e-10 40.9 0.0 6.2e-09 35.8 0.0 2.1 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Ysc84 PF04366.12 KPA36007.1 - 9.8e-27 93.2 0.0 1.7e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Ank_2 PF12796.7 KPA36008.1 - 4.9e-32 110.4 3.0 4e-18 65.8 0.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KPA36008.1 - 1.3e-20 72.8 0.6 8.2e-07 29.2 0.2 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KPA36008.1 - 1.6e-19 70.0 0.1 2.2e-12 47.2 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA36008.1 - 9.6e-19 67.2 1.2 1.2e-08 35.1 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA36008.1 - 1.9e-18 64.6 0.2 5.9e-06 26.2 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat DDE_1 PF03184.19 KPA36009.1 - 5.6e-13 48.9 0.0 9.4e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SAP PF02037.27 KPA36009.1 - 3.7e-08 32.9 2.7 8.5e-08 31.8 2.7 1.6 1 0 0 1 1 1 1 SAP domain HTH_Tnp_Tc5 PF03221.16 KPA36009.1 - 3.9e-06 26.8 1.1 1.6e-05 24.8 0.6 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KPA36009.1 - 2e-05 24.4 0.1 0.00014 21.7 0.1 2.4 2 0 0 2 2 2 1 DDE superfamily endonuclease AntA PF08346.12 KPA36009.1 - 0.003 18.1 0.4 1.1 9.9 0.1 2.6 2 0 0 2 2 2 1 AntA/AntB antirepressor DUF3223 PF11523.8 KPA36009.1 - 0.02 15.7 0.1 2.7 8.9 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3223) Uso1_p115_C PF04871.13 KPA36009.1 - 1.7 9.0 5.5 1.4 9.3 2.7 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FMO-like PF00743.19 KPA36010.1 - 2e-19 69.4 0.0 1.9e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPA36010.1 - 5.7e-16 58.6 0.0 1.4e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA36010.1 - 1.3e-13 50.9 0.0 3.1e-09 36.9 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPA36010.1 - 8.4e-13 48.2 0.0 3.4e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA36010.1 - 4.9e-11 42.4 0.0 1.6e-08 34.1 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KPA36010.1 - 1.8e-06 27.8 0.1 0.0039 16.8 0.1 3.9 3 2 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPA36010.1 - 3.4e-05 23.9 0.1 2.1 8.3 0.1 3.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 KPA36010.1 - 4.5e-05 23.9 0.0 0.6 10.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KPA36010.1 - 0.00037 20.7 0.0 0.0092 16.2 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Lycopene_cycl PF05834.12 KPA36010.1 - 0.00037 19.7 0.0 0.17 10.9 0.0 2.7 2 1 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 KPA36010.1 - 0.00063 19.1 0.0 0.12 11.6 0.0 2.5 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.16 KPA36010.1 - 0.0034 17.0 0.1 0.087 12.5 0.0 2.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KPA36010.1 - 0.0065 17.0 0.0 0.23 12.0 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.14 KPA36010.1 - 0.007 15.1 0.1 1.1 7.9 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 KPA36010.1 - 0.01 14.9 0.0 0.04 13.0 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KPA36010.1 - 0.021 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KPA36010.1 - 0.028 14.8 0.1 0.14 12.6 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 KPA36010.1 - 0.055 12.5 0.1 1.1 8.2 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 KPA36010.1 - 0.093 12.8 0.0 0.45 10.6 0.0 2.1 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KPA36010.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding GlgX_C PF18390.1 KPA36011.1 - 0.12 12.1 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 Glycogen debranching enzyme C-terminal domain Ank_2 PF12796.7 KPA36012.1 - 7.8e-20 71.3 3.0 6.2e-07 29.9 0.2 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA36012.1 - 3.3e-14 53.0 5.5 5e-07 30.2 0.1 5.1 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA36012.1 - 1.6e-11 44.2 0.4 0.00049 20.3 0.0 4.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KPA36012.1 - 1.9e-10 40.7 0.2 0.34 11.4 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KPA36012.1 - 2.7e-09 36.5 2.5 0.068 13.7 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat RelA_SpoT PF04607.17 KPA36012.1 - 2.5e-08 34.2 0.0 2.1e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins NACHT PF05729.12 KPA36012.1 - 4.2e-05 23.5 0.0 0.00013 22.0 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Gtr1_RagA PF04670.12 KPA36012.1 - 0.053 12.9 0.1 0.096 12.0 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_30 PF13604.6 KPA36012.1 - 0.058 13.1 0.2 0.27 10.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain Peptidase_S10 PF00450.22 KPA36013.1 - 1.9e-25 90.1 0.0 2.2e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Pribosyltran PF00156.27 KPA36014.1 - 1.4e-21 76.6 0.0 2.7e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain P-mevalo_kinase PF04275.14 KPA36014.1 - 3.2e-20 72.2 0.0 5.7e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Phosphomevalonate kinase FAD_binding_4 PF01565.23 KPA36014.1 - 6.4e-14 51.9 4.3 1.3e-13 50.9 4.3 1.6 1 0 0 1 1 1 1 FAD binding domain UPRTase PF14681.6 KPA36014.1 - 0.00014 21.4 0.0 0.00033 20.2 0.0 1.6 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BBE PF08031.12 KPA36014.1 - 0.0019 18.3 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_23 PF13489.6 KPA36014.1 - 0.0023 17.8 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PRTase_2 PF15609.6 KPA36014.1 - 0.017 14.7 0.0 0.045 13.3 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase Sigma54_activat PF00158.26 KPA36014.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Ceramidase_alk PF04734.13 KPA36015.1 - 8.1e-208 691.2 0.0 9.4e-208 690.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KPA36015.1 - 2.9e-56 189.9 0.1 4.5e-56 189.3 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal GLEYA PF10528.9 KPA36016.1 - 7.8e-27 93.5 0.0 2e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 KPA36016.1 - 5.2e-06 26.3 0.1 1.2e-05 25.1 0.1 1.6 1 1 0 1 1 1 1 PA14 domain LPD16 PF18830.1 KPA36016.1 - 0.23 11.4 0.3 0.53 10.3 0.3 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 16 DIM PF08194.12 KPA36016.1 - 1.7 8.9 2.9 3.3 8.0 0.2 2.5 2 0 0 2 2 2 0 DIM protein HET PF06985.11 KPA36017.1 - 4.6e-23 82.2 1.6 6.9e-23 81.6 1.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 KPA36018.1 - 2.1e-10 40.5 7.2 4.3e-10 39.5 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA36018.1 - 5.4e-05 22.2 0.0 7.2e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KPA36019.1 - 2.8e-41 141.1 0.1 6.2e-41 140.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA36019.1 - 8.5e-30 104.0 0.0 1.3e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA36019.1 - 2.6e-10 40.5 0.6 1.4e-09 38.2 0.6 2.0 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KPA36019.1 - 0.0021 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KPA36019.1 - 0.0029 16.6 0.1 0.0042 16.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPA36019.1 - 0.0033 16.9 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KPA36019.1 - 0.02 14.3 0.3 0.02 14.3 0.3 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Abhydrolase_3 PF07859.13 KPA36020.1 - 7.3e-31 107.7 0.0 9.3e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPA36020.1 - 3.4e-12 45.9 0.0 5.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KPA36020.1 - 0.28 10.0 0.0 1.1 8.0 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family Pyr_redox_3 PF13738.6 KPA36021.1 - 4.1e-12 46.0 0.3 2.3e-11 43.5 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPA36021.1 - 4.2e-12 45.3 0.1 8.5e-11 41.0 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPA36021.1 - 1.7e-10 40.6 0.1 3.3e-08 33.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPA36021.1 - 2e-08 33.8 0.0 4.6e-07 29.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA36021.1 - 7.9e-08 31.8 0.0 7.1e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KPA36021.1 - 3.4e-07 30.4 0.0 1.1e-05 25.5 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA36021.1 - 0.00032 20.4 2.9 0.0014 18.2 0.8 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPA36021.1 - 0.0017 17.5 0.2 0.016 14.3 0.2 2.4 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.20 KPA36021.1 - 0.002 18.2 0.0 0.56 10.3 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KPA36021.1 - 0.0022 18.5 0.0 1.3 9.7 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KPA36021.1 - 0.0049 15.5 0.1 0.038 12.6 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 KPA36021.1 - 0.01 14.9 0.1 1.2 8.1 0.0 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein Amino_oxidase PF01593.24 KPA36021.1 - 0.044 13.1 0.0 0.087 12.1 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KPA36021.1 - 0.076 12.1 0.8 0.19 10.7 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KPA36021.1 - 0.12 11.1 0.4 1 8.0 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KPA36021.1 - 0.13 11.5 0.2 0.3 10.4 0.2 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPA36021.1 - 0.25 11.3 2.4 1.7 8.6 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding PDZ_1 PF12812.7 KPA36022.1 - 5.7e-24 83.9 0.0 1e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 PDZ-like domain PDZ_2 PF13180.6 KPA36022.1 - 1.7e-06 28.2 0.2 7e-06 26.3 0.1 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KPA36022.1 - 3.8e-05 23.5 1.6 8.7e-05 22.3 0.1 2.3 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 KPA36022.1 - 5.7e-05 23.4 0.1 0.00019 21.7 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Trypsin_2 PF13365.6 KPA36022.1 - 0.0055 17.6 0.2 0.011 16.7 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain TauD PF02668.16 KPA36024.1 - 9e-09 35.5 0.0 1.2e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NACHT PF05729.12 KPA36025.1 - 1.4e-16 60.9 0.0 7.8e-16 58.4 0.0 2.2 2 0 0 2 2 2 1 NACHT domain HEAT_2 PF13646.6 KPA36025.1 - 8.9e-09 35.6 0.2 2.3e-08 34.3 0.2 1.7 1 0 0 1 1 1 1 HEAT repeats NB-ARC PF00931.22 KPA36025.1 - 1e-08 34.7 0.0 2.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KPA36025.1 - 2.7e-06 27.7 0.0 2.2e-05 24.8 0.0 2.5 3 0 0 3 3 2 1 AAA domain DUF676 PF05057.14 KPA36025.1 - 0.00061 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 KPA36025.1 - 0.00076 19.9 0.0 0.0035 17.8 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain NLRC4_HD2 PF17776.1 KPA36025.1 - 0.00076 20.0 0.0 0.0024 18.4 0.0 1.9 1 0 0 1 1 1 1 NLRC4 helical domain HD2 PGAP1 PF07819.13 KPA36025.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KPA36025.1 - 0.005 17.5 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family HEAT PF02985.22 KPA36025.1 - 0.017 15.3 0.1 2 8.9 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat TsaE PF02367.17 KPA36025.1 - 0.025 14.6 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KPA36025.1 - 0.034 14.2 0.1 0.4 10.7 0.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPA36025.1 - 0.037 14.6 0.0 0.13 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain LCAT PF02450.15 KPA36025.1 - 0.051 12.7 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase RNA_helicase PF00910.22 KPA36025.1 - 0.07 13.5 0.0 0.62 10.5 0.0 2.6 4 0 0 4 4 3 0 RNA helicase NTPase_1 PF03266.15 KPA36025.1 - 0.07 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 NTPase Hydrolase_4 PF12146.8 KPA36025.1 - 0.084 12.1 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AAA_24 PF13479.6 KPA36025.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain LIDHydrolase PF10230.9 KPA36025.1 - 0.14 11.7 0.0 1.7 8.1 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase HEAT_EZ PF13513.6 KPA36025.1 - 0.14 12.7 0.3 6.1 7.5 0.0 2.9 2 1 1 3 3 2 0 HEAT-like repeat PduV-EutP PF10662.9 KPA36025.1 - 0.15 11.8 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation DUF4013 PF13197.6 KPA36026.1 - 0.0036 17.2 1.0 0.0061 16.4 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) DHHC PF01529.20 KPA36026.1 - 0.09 12.9 2.5 0.16 12.1 2.5 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase RDD PF06271.12 KPA36026.1 - 0.1 12.8 3.8 0.22 11.7 3.8 1.6 1 0 0 1 1 1 0 RDD family Herpes_Helicase PF02689.14 KPA36026.1 - 0.1 10.5 0.2 0.13 10.2 0.2 1.1 1 0 0 1 1 1 0 Helicase PGF-CTERM PF18204.1 KPA36026.1 - 0.28 11.2 2.8 1 9.4 2.8 2.0 1 0 0 1 1 1 0 PGF-CTERM motif Vfa1 PF08432.10 KPA36027.1 - 1.5 9.1 25.6 8.5 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Mitofilin PF09731.9 KPA36027.1 - 2.1 7.1 27.2 3.4 6.4 27.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC45 PF02724.14 KPA36027.1 - 4.1 5.6 22.4 5.7 5.1 22.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF5516 PF17637.2 KPA36027.1 - 8.8 6.2 7.3 22 4.9 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5516) PHM7_cyt PF14703.6 KPA36028.1 - 0.19 11.9 1.7 0.38 11.0 1.7 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter CorA PF01544.18 KPA36032.1 - 1.3e-09 37.8 0.4 2.4e-09 36.9 0.4 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sugar_tr PF00083.24 KPA36033.1 - 4.4e-122 408.2 21.2 5.1e-122 408.0 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36033.1 - 2.7e-25 89.1 42.7 6.5e-22 77.9 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M85 PF13678.6 KPA36035.1 - 0.016 14.8 0.2 0.039 13.6 0.0 1.6 2 0 0 2 2 2 0 NFkB-p65-degrading zinc protease FAM76 PF16046.5 KPA36035.1 - 0.018 14.4 2.0 0.021 14.2 2.0 1.2 1 0 0 1 1 1 0 FAM76 protein OPT PF03169.15 KPA36036.1 - 5.9e-174 580.1 43.9 6.7e-174 579.9 43.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MutS_V PF00488.21 KPA36038.1 - 3.6e-33 115.2 0.0 6.1e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KPA36038.1 - 0.00014 22.2 0.0 0.00024 21.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KPA36038.1 - 0.069 13.5 0.1 0.14 12.5 0.1 1.6 1 1 0 1 1 1 0 MutS family domain IV Glyco_transf_90 PF05686.12 KPA36041.1 - 3.4e-14 52.6 1.1 2.4e-11 43.2 0.4 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 PAP1 PF08601.10 KPA36042.1 - 5.3 6.7 6.7 4.8 6.8 5.4 1.3 1 1 0 1 1 1 0 Transcription factor PAP1 Aldo_ket_red PF00248.21 KPA36044.1 - 6.4e-60 202.8 0.0 7.8e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Metal_resist PF13801.6 KPA36044.1 - 0.059 13.6 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Helicase_C PF00271.31 KPA36046.1 - 5.7e-05 23.4 0.2 0.00028 21.2 0.1 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF2753 PF10952.8 KPA36046.1 - 0.13 12.4 2.2 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2753) OrsD PF12013.8 KPA36047.1 - 3.2e-17 63.0 0.4 6e-17 62.1 0.4 1.4 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 KPA36047.1 - 0.05 13.9 0.5 1.9 8.9 0.6 2.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 KPA36047.1 - 0.051 12.7 0.2 0.32 10.1 0.2 2.0 1 1 0 1 1 1 0 Putative actin-like family KRAB PF01352.27 KPA36047.1 - 0.38 10.5 1.3 0.82 9.4 1.3 1.5 1 0 0 1 1 1 0 KRAB box Rx_N PF18052.1 KPA36047.1 - 1.5 9.2 5.9 1.7 9.0 1.6 2.8 3 0 0 3 3 3 0 Rx N-terminal domain HET PF06985.11 KPA36049.1 - 2.8e-11 44.0 10.7 9.3e-09 35.8 3.4 2.6 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Transp_cyt_pur PF02133.15 KPA36051.1 - 5.2e-82 276.0 37.0 5.9e-82 275.8 37.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.25 KPA36052.1 - 3.2e-37 127.9 0.0 3.9e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA36052.1 - 2.9e-32 112.1 0.0 3.8e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KPA36052.1 - 2.4e-05 23.6 0.0 9e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KPA36052.1 - 2.5e-05 24.3 0.1 3.9e-05 23.7 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA36052.1 - 0.012 15.1 0.0 3.8 6.9 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 KPA36053.1 - 0.0002 20.5 2.8 0.00022 20.3 0.2 2.4 3 1 0 3 3 3 1 Fungal specific transcription factor domain FMO-like PF00743.19 KPA36054.1 - 2.5e-15 55.9 0.5 1.4e-12 46.8 0.1 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPA36054.1 - 5.8e-11 42.5 0.1 2.9e-10 40.2 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPA36054.1 - 1.9e-06 27.3 0.1 0.00026 20.3 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPA36054.1 - 2.5e-06 27.0 0.0 7.2e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA36054.1 - 0.034 13.4 0.1 0.51 9.5 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA36054.1 - 0.11 12.4 3.8 0.13 12.3 0.0 2.9 4 0 0 4 4 4 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KPA36054.1 - 0.19 12.3 0.1 91 3.7 0.0 3.7 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 KPA36055.1 - 1.1e-97 327.8 18.2 1.2e-97 327.6 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36055.1 - 2.8e-34 118.6 37.3 1.4e-30 106.4 19.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NnrU PF07298.11 KPA36055.1 - 0.13 11.7 2.8 2.3 7.7 0.3 2.5 2 0 0 2 2 2 0 NnrU protein Glyco_hydro_43 PF04616.14 KPA36056.1 - 2.6e-18 66.4 3.8 2.6e-18 66.4 3.8 1.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 43 NACHT_N PF17100.5 KPA36057.1 - 7.2e-84 281.1 4.7 1.4e-83 280.1 2.2 2.3 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 KPA36057.1 - 3.8e-38 128.8 7.1 6.2e-12 45.9 0.4 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat NACHT PF05729.12 KPA36057.1 - 3.4e-19 69.3 0.5 4.6e-18 65.7 0.1 2.7 3 0 0 3 3 3 1 NACHT domain ANAPC4_WD40 PF12894.7 KPA36057.1 - 1.8e-13 50.5 0.2 0.0013 19.0 0.0 3.9 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA36057.1 - 8.3e-07 28.3 1.1 0.00093 18.2 0.4 2.7 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KPA36057.1 - 0.0004 19.2 0.4 1.5 7.3 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KPA36057.1 - 0.0096 15.3 0.0 1.9 7.7 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain PD40 PF07676.12 KPA36057.1 - 0.015 15.3 0.1 73 3.5 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KPA36057.1 - 0.015 13.9 0.1 0.027 13.0 0.1 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain AAA_22 PF13401.6 KPA36057.1 - 0.025 14.8 0.2 0.24 11.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KPA36057.1 - 0.051 13.4 0.2 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KPA36057.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KPA36057.1 - 0.75 9.0 2.8 10 5.3 0.3 2.9 2 1 1 3 3 3 0 KAP family P-loop domain Rx_N PF18052.1 KPA36057.1 - 3.5 8.0 6.9 0.62 10.4 1.3 2.8 3 0 0 3 3 2 0 Rx N-terminal domain Ppx-GppA PF02541.16 KPA36059.1 - 8.3e-05 22.1 0.1 0.00019 21.0 0.0 1.6 2 0 0 2 2 2 1 Ppx/GppA phosphatase family Cellulase PF00150.18 KPA36060.1 - 3.3e-06 26.7 0.6 0.00037 20.0 0.2 2.3 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Transp_cyt_pur PF02133.15 KPA36061.1 - 2.1e-21 76.3 38.6 3.3e-21 75.6 37.9 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Caveolin PF01146.17 KPA36061.1 - 0.43 10.5 0.0 0.43 10.5 0.0 2.3 3 0 0 3 3 3 0 Caveolin Glyco_transf_64 PF09258.10 KPA36062.1 - 1.1e-37 129.6 0.0 1.7e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain GST_N_3 PF13417.6 KPA36063.1 - 6e-19 68.2 0.0 9.5e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPA36063.1 - 4.1e-18 65.4 0.0 6.6e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPA36063.1 - 3.2e-11 43.4 0.1 4.9e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain XAP5 PF04921.14 KPA36064.1 - 1.4e-93 313.3 0.0 2.3e-93 312.6 0.0 1.3 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 KPA36064.1 - 0.00032 21.2 5.5 0.00032 21.2 5.5 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4604) ORC6 PF05460.13 KPA36064.1 - 0.39 9.9 5.9 0.6 9.3 5.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FMN_bind_2 PF04299.12 KPA36066.1 - 6.5e-58 195.1 0.0 1e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 Putative FMN-binding domain AATase PF07247.12 KPA36067.1 - 2.4e-11 42.9 0.0 2.2e-10 39.7 0.0 2.2 1 1 1 2 2 2 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 KPA36067.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain RcnB PF11776.8 KPA36068.1 - 0.05 13.7 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator Retinal PF15449.6 KPA36069.1 - 9.3 3.9 12.2 8.8 4.0 12.2 1.0 1 0 0 1 1 1 0 Retinal protein AATase PF07247.12 KPA36070.1 - 2.1e-23 82.7 0.0 8.3e-23 80.7 0.0 1.7 1 1 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 KPA36070.1 - 0.0044 16.8 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 KPA36070.1 - 0.01 14.5 0.0 0.11 11.1 0.0 2.0 2 0 0 2 2 2 0 Condensation domain Peptidase_M75 PF09375.10 KPA36070.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Imelysin adh_short_C2 PF13561.6 KPA36072.1 - 8.3e-63 212.1 4.3 7.6e-53 179.5 0.5 3.0 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA36072.1 - 1.3e-49 168.3 9.0 3.2e-33 114.9 0.6 3.0 1 1 2 3 3 3 3 short chain dehydrogenase KR PF08659.10 KPA36072.1 - 6.6e-05 22.9 0.2 0.05 13.5 0.1 2.3 2 0 0 2 2 2 2 KR domain ADC PF06314.11 KPA36073.1 - 4e-25 88.8 0.0 4.9e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) DUF1857 PF08982.11 KPA36075.1 - 6.3e-55 185.1 0.1 7.1e-55 184.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) SSF PF00474.17 KPA36076.1 - 2.8e-21 75.9 30.6 4.3e-21 75.3 30.6 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family CoA_binding_3 PF13727.6 KPA36076.1 - 0.0025 17.8 8.2 0.4 10.7 0.1 3.0 2 0 0 2 2 2 2 CoA-binding domain ARL6IP6 PF15062.6 KPA36076.1 - 0.3 11.2 1.6 6.8 6.9 0.1 2.9 3 0 0 3 3 3 0 Haemopoietic lineage transmembrane helix COesterase PF00135.28 KPA36077.1 - 3.5e-92 309.9 0.0 4.5e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA36077.1 - 4.1e-06 26.8 0.1 1.6e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA36077.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Asparaginase_II PF06089.12 KPA36078.1 - 7.2e-117 390.0 2.1 8.1e-117 389.8 2.1 1.0 1 0 0 1 1 1 1 L-asparaginase II Pap_E4 PF02711.14 KPA36079.1 - 0.034 15.1 3.0 0.048 14.6 3.0 1.3 1 0 0 1 1 1 0 E4 protein PBP1_TM PF14812.6 KPA36079.1 - 0.038 14.4 14.1 0.024 15.0 12.5 1.5 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MCM_bind PF09739.9 KPA36079.1 - 0.24 9.8 7.1 0.26 9.7 7.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Pox_Ag35 PF03286.14 KPA36079.1 - 0.35 10.6 8.6 0.38 10.5 8.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Suf PF05843.14 KPA36079.1 - 1.4 8.9 9.8 1.4 8.9 9.8 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 KPA36079.1 - 2.6 6.9 12.7 2.8 6.8 12.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ferlin_C PF16165.5 KPA36079.1 - 3.3 7.7 4.9 4 7.4 4.9 1.1 1 0 0 1 1 1 0 Ferlin C-terminus RR_TM4-6 PF06459.12 KPA36079.1 - 4.1 7.1 11.1 4.3 7.1 11.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PNISR PF15996.5 KPA36079.1 - 4.3 7.5 17.1 5.3 7.3 17.1 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Rrn6 PF10214.9 KPA36079.1 - 4.3 5.7 13.3 4.5 5.6 13.3 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FAM60A PF15396.6 KPA36079.1 - 4.5 7.2 9.2 4.6 7.2 9.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PTPRCAP PF15713.5 KPA36079.1 - 4.9 7.4 15.2 6.5 7.0 15.2 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Neur_chan_memb PF02932.16 KPA36079.1 - 9.6 6.2 7.9 11 6.0 7.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ank_2 PF12796.7 KPA36080.1 - 2.7e-15 56.7 0.1 1.8e-07 31.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA36080.1 - 8.4e-11 41.1 0.1 0.15 12.7 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KPA36080.1 - 8.1e-10 39.0 0.0 0.053 14.1 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KPA36080.1 - 1.9e-09 37.6 0.3 0.29 11.6 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KPA36080.1 - 7.2e-08 32.6 0.2 0.0019 18.5 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) F-box-like PF12937.7 KPA36080.1 - 2.2e-05 24.3 0.1 4.1e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA36080.1 - 0.02 14.8 1.0 0.041 13.8 1.0 1.5 1 0 0 1 1 1 0 F-box domain MFS_1 PF07690.16 KPA36081.1 - 8.2e-31 107.2 21.3 1.3e-30 106.6 21.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA36081.1 - 2.3e-08 33.3 6.8 2.3e-08 33.3 6.8 2.5 2 2 0 2 2 2 1 Sugar (and other) transporter Folate_carrier PF01770.18 KPA36081.1 - 0.0004 19.3 0.0 0.00057 18.7 0.0 1.2 1 0 0 1 1 1 1 Reduced folate carrier MFS_1_like PF12832.7 KPA36081.1 - 0.0021 17.0 2.0 0.0021 17.0 2.0 1.9 2 0 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 KPA36081.1 - 0.0022 16.4 1.5 0.0022 16.4 1.5 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector CENP-B_dimeris PF09026.10 KPA36081.1 - 1.8 9.0 3.9 24 5.4 1.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Fungal_trans PF04082.18 KPA36082.1 - 3.8e-13 49.1 0.8 8e-13 48.0 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA36082.1 - 7.3e-06 26.0 3.9 1.2e-05 25.3 3.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup84_Nup100 PF04121.13 KPA36083.1 - 0.026 12.6 0.1 0.029 12.5 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 Pyr_redox_2 PF07992.14 KPA36084.1 - 1.1e-06 28.1 0.0 4.1e-05 22.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPA36084.1 - 1.6e-06 26.8 0.0 3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPA36084.1 - 2.6e-06 26.8 0.0 8.2e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPA36084.1 - 4.8e-06 26.7 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPA36084.1 - 0.0097 15.9 0.0 0.32 11.0 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding DUF3288 PF11691.8 KPA36084.1 - 0.16 12.0 0.2 0.33 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) B1 PF02246.15 KPA36085.1 - 0.032 14.3 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein L b1 domain Peptidase_M60 PF13402.6 KPA36085.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like PAN_4 PF14295.6 KPA36086.1 - 0.057 13.3 2.7 8.4 6.4 0.2 2.8 2 0 0 2 2 2 0 PAN domain Cerato-platanin PF07249.12 KPA36087.1 - 6e-17 61.9 0.2 7.3e-17 61.6 0.2 1.1 1 0 0 1 1 1 1 Cerato-platanin MFS_1 PF07690.16 KPA36088.1 - 1.4e-33 116.3 43.7 1.4e-33 116.3 43.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA36088.1 - 7.8e-07 27.9 4.9 1.3e-06 27.1 4.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_3 PF07859.13 KPA36089.1 - 2.1e-53 181.3 0.0 3.1e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPA36089.1 - 0.00061 18.8 0.0 0.00076 18.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase LIDHydrolase PF10230.9 KPA36089.1 - 0.0066 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 KPA36089.1 - 0.01 14.8 0.0 0.024 13.6 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KPA36089.1 - 0.091 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KPA36089.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase HET PF06985.11 KPA36090.1 - 7e-25 88.1 0.0 1.6e-24 86.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TRI5 PF06330.11 KPA36091.1 - 1.4e-185 616.4 4.4 1.7e-185 616.1 4.4 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF1816 PF08846.10 KPA36091.1 - 0.005 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1816) USP7_ICP0_bdg PF12436.8 KPA36091.1 - 0.013 14.9 3.5 0.013 14.9 0.8 2.2 2 1 1 3 3 3 0 ICP0-binding domain of Ubiquitin-specific protease 7 DUF2935 PF11155.8 KPA36091.1 - 0.019 15.3 0.3 0.055 13.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF3086 PF11285.8 KPA36092.1 - 0.00082 18.6 0.9 0.00088 18.5 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) CtIP_N PF10482.9 KPA36092.1 - 0.013 15.6 4.3 0.013 15.6 4.3 1.8 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain CCDC-167 PF15188.6 KPA36092.1 - 0.013 15.8 2.4 0.021 15.2 2.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 NPV_P10 PF05531.12 KPA36092.1 - 0.013 15.9 3.4 0.23 12.0 1.3 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 KPA36092.1 - 0.017 15.2 2.0 0.022 14.8 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Med3 PF11593.8 KPA36092.1 - 0.018 14.2 0.4 0.02 14.1 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4600 PF15372.6 KPA36092.1 - 0.021 15.2 3.6 0.024 15.1 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) PCRF PF03462.18 KPA36092.1 - 0.022 14.6 2.1 0.025 14.4 2.1 1.1 1 0 0 1 1 1 0 PCRF domain GerPC PF10737.9 KPA36092.1 - 0.026 14.6 2.3 0.046 13.8 2.3 1.5 1 1 0 1 1 1 0 Spore germination protein GerPC DASH_Dam1 PF08653.10 KPA36092.1 - 0.026 14.3 0.2 2.4 8.0 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 GIT_CC PF16559.5 KPA36092.1 - 0.027 14.3 3.2 0.075 12.9 2.1 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 KPA36092.1 - 0.039 14.0 2.2 4.6 7.3 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KPA36092.1 - 0.051 14.0 4.3 3.8 8.0 0.1 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Serine_rich PF08824.10 KPA36092.1 - 0.055 13.5 1.3 0.087 12.8 1.1 1.5 1 1 0 1 1 1 0 Serine rich protein interaction domain TPR_MLP1_2 PF07926.12 KPA36092.1 - 0.093 12.8 6.2 0.25 11.4 6.2 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FapA PF03961.13 KPA36092.1 - 0.11 11.1 5.9 0.17 10.5 5.9 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A zf-C4H2 PF10146.9 KPA36092.1 - 0.11 12.8 3.4 0.17 12.2 3.4 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein GAS PF13851.6 KPA36092.1 - 0.13 11.6 8.3 0.27 10.5 7.7 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 KPA36092.1 - 0.14 12.4 4.9 1.6 9.1 2.5 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 KPA36092.1 - 0.18 12.3 4.6 0.31 11.6 4.6 1.5 1 1 0 1 1 1 0 Spectrin repeat bZIP_1 PF00170.21 KPA36092.1 - 0.24 11.5 9.6 0.64 10.2 6.7 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF4140 PF13600.6 KPA36092.1 - 0.25 11.8 5.1 13 6.3 3.2 2.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 KPA36092.1 - 0.33 11.5 10.2 0.61 10.6 7.4 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Fungal_TACC PF12709.7 KPA36092.1 - 0.35 11.4 6.6 12 6.4 0.0 2.1 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins ABC_tran_CTD PF16326.5 KPA36092.1 - 0.55 10.5 6.2 2.4 8.5 3.0 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain E2F_CC-MB PF16421.5 KPA36092.1 - 0.62 10.5 4.2 5.5 7.4 2.1 2.1 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain Seryl_tRNA_N PF02403.22 KPA36092.1 - 0.91 9.8 7.8 3.8 7.8 7.8 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.18 KPA36092.1 - 1.2 9.5 5.3 1.2 9.5 2.1 2.2 2 1 0 2 2 2 0 TSC-22/dip/bun family Histone PF00125.24 KPA36093.1 - 2e-42 144.6 0.5 2.3e-42 144.4 0.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KPA36093.1 - 0.00018 21.6 0.2 0.00028 21.0 0.2 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KPA36093.1 - 0.00031 21.0 0.1 0.00046 20.5 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KPA36093.1 - 0.011 16.1 0.2 0.015 15.6 0.2 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KPA36093.1 - 0.13 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit VWA PF00092.28 KPA36094.1 - 2.6e-07 31.0 0.0 3.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KPA36094.1 - 0.00017 22.2 0.0 0.00041 21.0 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KPA36094.1 - 0.0015 18.5 0.0 0.0077 16.2 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KPA36094.1 - 0.0018 18.4 0.0 0.004 17.3 0.0 1.5 1 1 0 1 1 1 1 vWA found in TerF C terminus Transformer PF06495.11 KPA36095.1 - 0.013 15.6 10.6 0.014 15.5 9.5 1.6 2 0 0 2 2 2 0 Fruit fly transformer protein Apis_Csd PF11671.8 KPA36095.1 - 4.3 7.3 9.4 6.4 6.8 9.4 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Glyco_hydro_16 PF00722.21 KPA36096.1 - 2.8e-39 134.4 4.6 2.8e-39 134.4 4.6 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Abhydrolase_6 PF12697.7 KPA36097.1 - 1.7e-17 64.8 0.2 2.2e-17 64.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA36097.1 - 8.5e-16 58.4 0.0 1.4e-13 51.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA36097.1 - 1.6e-05 24.3 0.0 2.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KPA36097.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase MFS_1 PF07690.16 KPA36098.1 - 5.3e-16 58.5 37.0 7.1e-16 58.1 37.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily COesterase PF00135.28 KPA36099.1 - 1.8e-86 291.1 0.0 2.1e-86 290.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA36099.1 - 3.4e-07 30.3 0.0 6.2e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA36099.1 - 0.041 13.4 0.7 0.062 12.8 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family FAD_binding_4 PF01565.23 KPA36100.1 - 1.4e-21 76.7 0.2 2.5e-21 75.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPA36100.1 - 0.00076 19.5 0.0 0.0026 17.8 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like DUF3984 PF13136.6 KPA36101.1 - 5.8e-62 210.0 26.8 7.3e-61 206.4 26.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) Hpt PF01627.23 KPA36102.1 - 2.7e-14 53.2 0.0 4.1e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Hpt domain RelB_N PF18506.1 KPA36102.1 - 0.048 13.5 7.8 1.8 8.4 3.4 2.6 2 0 0 2 2 2 0 RelB Antitoxin alpha helical domain DUF3225 PF11533.8 KPA36102.1 - 0.06 13.1 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) NusB PF01029.18 KPA36102.1 - 0.066 13.5 0.0 2.7 8.2 0.0 2.1 2 0 0 2 2 2 0 NusB family Tim44 PF04280.15 KPA36102.1 - 0.12 12.4 0.3 0.24 11.5 0.2 1.5 1 1 0 1 1 1 0 Tim44-like domain HET PF06985.11 KPA36103.1 - 2.2e-25 89.7 0.1 9.1e-25 87.7 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Read-through PF16814.5 KPA36104.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Read-through domain ADH_zinc_N PF00107.26 KPA36106.1 - 3e-13 49.9 0.1 6.2e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA36106.1 - 0.00069 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KPA36106.1 - 0.017 14.4 0.3 0.029 13.7 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KPA36106.1 - 0.13 13.3 0.2 4.9 8.2 0.0 2.8 2 1 1 3 3 3 0 Zinc-binding dehydrogenase HET PF06985.11 KPA36108.1 - 4.1e-22 79.1 0.0 9.3e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 KPA36109.1 - 3.1e-54 184.0 0.8 3.8e-54 183.7 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA36109.1 - 1.5e-45 155.1 0.6 1.8e-45 154.8 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA36109.1 - 4.9e-09 36.4 0.0 6.4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA36109.1 - 0.004 16.7 0.1 0.017 14.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 KPA36109.1 - 0.027 14.4 0.2 0.042 13.7 0.2 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 KPA36109.1 - 0.059 13.2 0.1 0.091 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.18 KPA36110.1 - 7.8e-10 38.7 10.0 1.8e-09 37.6 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MMS19_N PF14500.6 KPA36113.1 - 0.13 11.8 0.1 0.43 10.1 0.0 1.7 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Guanylate_kin PF00625.21 KPA36114.1 - 1.8e-48 164.6 0.0 2.2e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase RsgA_GTPase PF03193.16 KPA36114.1 - 0.00054 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KPA36114.1 - 0.0019 18.6 0.0 0.0025 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KPA36114.1 - 0.0024 17.9 0.0 0.0036 17.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KPA36114.1 - 0.0077 16.4 0.1 0.088 13.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KPA36114.1 - 0.029 14.8 0.0 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 KPA36114.1 - 0.031 14.8 0.0 0.039 14.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KPA36114.1 - 0.036 14.4 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPA36114.1 - 0.036 14.6 1.2 0.15 12.6 1.2 2.1 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KPA36114.1 - 0.038 13.9 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 NTPase cobW PF02492.19 KPA36114.1 - 0.1 12.2 0.1 0.39 10.3 0.0 2.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KPA36114.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KPA36114.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KPA36114.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain dNK PF01712.19 KPA36114.1 - 0.15 11.9 0.2 7 6.4 0.0 2.3 2 1 0 2 2 2 0 Deoxynucleoside kinase zf-MYND PF01753.18 KPA36116.1 - 7.2e-08 32.4 10.0 1.1e-07 31.8 10.0 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KPA36116.1 - 2.1 8.5 7.3 4 7.6 7.3 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PIF1 PF05970.14 KPA36117.1 - 2.4e-34 119.1 0.2 5.3e-24 85.1 0.0 3.1 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 KPA36117.1 - 3.1e-20 72.7 0.0 1.3e-16 60.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KPA36117.1 - 1.3e-10 41.8 0.0 3.4e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KPA36117.1 - 2.5e-07 30.7 0.1 0.0024 17.6 0.1 2.5 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KPA36117.1 - 1.4e-05 25.0 1.6 0.004 17.1 1.6 2.5 1 1 0 1 1 1 1 NTPase Herpes_Helicase PF02689.14 KPA36117.1 - 2e-05 22.8 0.1 0.0023 15.9 0.0 3.0 3 1 0 4 4 4 1 Helicase AAA PF00004.29 KPA36117.1 - 0.00013 22.4 0.0 0.00026 21.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA36117.1 - 0.00015 22.1 0.0 0.00041 20.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KPA36117.1 - 0.0012 18.6 0.0 0.0041 16.9 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 KPA36117.1 - 0.0014 19.1 0.0 0.0036 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 KPA36117.1 - 0.0019 18.2 0.1 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KPA36117.1 - 0.0019 18.2 0.0 0.0075 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KPA36117.1 - 0.0031 17.3 0.1 0.013 15.3 0.1 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase MeaB PF03308.16 KPA36117.1 - 0.0054 15.8 0.1 0.009 15.0 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KPA36117.1 - 0.0062 17.1 0.0 0.014 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KPA36117.1 - 0.012 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KPA36117.1 - 0.013 15.6 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KPA36117.1 - 0.023 14.2 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KPA36117.1 - 0.027 14.5 0.0 0.19 11.7 0.0 2.4 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KPA36117.1 - 0.029 13.6 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 KPA36117.1 - 0.034 14.1 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Bac_DnaA PF00308.18 KPA36117.1 - 0.039 13.8 0.1 0.28 11.0 0.1 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_16 PF13191.6 KPA36117.1 - 0.045 14.1 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KPA36117.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KPA36117.1 - 0.072 13.0 0.0 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain T2SSE PF00437.20 KPA36117.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 KPA36117.1 - 0.12 12.8 0.2 0.47 10.9 0.2 2.1 1 1 0 1 1 1 0 RNA helicase Microtub_bd PF16796.5 KPA36117.1 - 0.14 12.1 0.0 25 4.8 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding PhoH PF02562.16 KPA36117.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_POL_M_15KD PF02150.16 KPA36117.1 - 0.24 11.3 4.0 0.54 10.2 4.0 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit NACHT PF05729.12 KPA36118.1 - 0.00017 21.6 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KPA36118.1 - 0.00057 19.2 0.2 0.0017 17.6 0.2 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily AA_permease_2 PF13520.6 KPA36119.1 - 1.8e-49 168.8 38.4 2.3e-49 168.4 38.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA36119.1 - 1.2e-17 63.7 28.9 1.6e-17 63.3 28.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2516 PF10724.9 KPA36119.1 - 0.16 12.3 7.6 4.8 7.5 2.6 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2516) zf-C2H2_3 PF13878.6 KPA36119.1 - 0.31 10.9 0.5 1.9 8.4 0.2 2.1 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO PI31_Prot_N PF11566.8 KPA36120.1 - 6.2e-51 172.4 0.0 7.1e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal Baculo_LEF-2 PF03041.14 KPA36120.1 - 0.02 14.5 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 lef-2 PI31_Prot_C PF08577.11 KPA36121.1 - 2e-18 67.3 17.3 2e-18 67.3 17.3 2.5 3 0 0 3 3 3 1 PI31 proteasome regulator DUF3435 PF11917.8 KPA36123.1 - 5.9e-40 137.5 4.4 1e-28 100.4 0.0 3.4 3 1 1 4 4 4 3 Protein of unknown function (DUF3435) FOXP-CC PF16159.5 KPA36123.1 - 1.4 9.6 5.7 0.31 11.7 1.1 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain BTB PF00651.31 KPA36124.1 - 0.0014 18.8 0.0 0.0069 16.6 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF4680 PF15730.5 KPA36124.1 - 0.21 12.0 0.0 0.27 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Peptidase_M24 PF00557.24 KPA36125.1 - 3.2e-21 76.0 0.0 5.6e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KPA36125.1 - 3.3e-19 69.9 0.0 5.8e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Lyase_1 PF00206.20 KPA36126.1 - 4.3e-34 118.3 0.0 7.6e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KPA36126.1 - 2.5e-10 41.0 0.0 5.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF676 PF05057.14 KPA36127.1 - 1.1e-05 25.1 0.0 2.2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KPA36127.1 - 2e-05 24.4 0.0 3.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KPA36127.1 - 0.00049 19.8 0.0 0.0017 18.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA36127.1 - 0.0075 16.9 0.0 0.029 15.0 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA36127.1 - 0.0083 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KPA36127.1 - 0.019 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LCAT PF02450.15 KPA36127.1 - 0.032 13.4 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.13 KPA36127.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase LIDHydrolase PF10230.9 KPA36127.1 - 0.068 12.7 0.1 0.92 9.0 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Homeobox_KN PF05920.11 KPA36128.1 - 2.1e-14 53.1 0.3 4.6e-14 52.0 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KPA36128.1 - 6.3e-08 32.5 0.5 0.0082 16.2 0.1 3.0 2 1 0 2 2 2 2 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KPA36128.1 - 2.1e-05 24.3 0.4 6.5e-05 22.7 0.4 1.9 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 KPA36128.1 - 0.0049 17.6 2.5 0.0049 17.6 2.5 4.1 4 0 0 4 4 4 1 C2H2-type zinc finger PSP PF04046.16 KPA36128.1 - 0.06 13.2 0.2 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 PSP DHQ_synthase PF01761.20 KPA36129.1 - 3.8e-45 154.1 0.0 5e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KPA36129.1 - 2.6e-10 40.4 0.0 3.5e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Vps16_C PF04840.12 KPA36130.1 - 0.02 14.0 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Vps16, C-terminal region TPR_10 PF13374.6 KPA36131.1 - 4.7e-42 140.7 18.5 1.1e-05 25.2 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat CHAT PF12770.7 KPA36131.1 - 5.9e-40 137.5 0.1 1.1e-39 136.6 0.1 1.5 1 0 0 1 1 1 1 CHAT domain TPR_8 PF13181.6 KPA36131.1 - 1.9e-22 77.5 12.0 0.13 12.5 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 KPA36131.1 - 4.9e-21 74.8 5.0 0.036 14.4 0.0 8.6 2 2 6 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KPA36131.1 - 2.7e-14 52.0 12.4 3.2 8.1 0.0 9.4 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KPA36131.1 - 5.4e-14 51.3 6.4 5.3 7.0 0.0 9.4 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF4404 PF14357.6 KPA36131.1 - 8.2e-14 52.0 12.6 0.011 16.4 0.2 6.7 2 1 5 7 7 6 6 Domain of unknown function (DUF4404) TPR_11 PF13414.6 KPA36131.1 - 1.9e-11 43.4 0.2 11 5.8 0.0 7.7 7 0 0 7 7 7 0 TPR repeat TPR_19 PF14559.6 KPA36131.1 - 1.9e-11 44.3 9.5 4.6 7.8 0.0 7.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPA36131.1 - 6.4e-11 42.7 5.6 0.0006 20.4 0.0 5.2 6 1 0 6 6 3 3 Tetratricopeptide repeat CENP-Q PF13094.6 KPA36131.1 - 6.2e-10 39.5 3.8 0.75 10.0 0.1 6.5 1 1 5 6 6 6 2 CENP-Q, a CENPA-CAD centromere complex subunit EAP30 PF04157.16 KPA36131.1 - 7.4e-09 35.2 0.0 1.7 7.9 0.0 5.4 1 1 4 5 5 5 3 EAP30/Vps36 family TPR_MalT PF17874.1 KPA36131.1 - 3.2e-08 33.3 1.2 5.1e-05 22.8 0.1 3.8 1 1 2 3 3 3 2 MalT-like TPR region TPR_14 PF13428.6 KPA36131.1 - 3.4e-08 33.6 23.8 4.5 8.3 0.0 8.8 11 0 0 11 11 7 1 Tetratricopeptide repeat PhageMin_Tail PF10145.9 KPA36131.1 - 2e-06 27.8 0.3 1.1 9.1 0.3 5.7 1 1 1 2 2 2 1 Phage-related minor tail protein GP3_package PF16677.5 KPA36131.1 - 7.1e-06 26.1 0.3 3.5 7.8 0.0 4.4 2 1 1 4 4 4 2 DNA-packaging protein gp3 TFA2_Winged_2 PF18121.1 KPA36131.1 - 2.1e-05 24.1 2.7 37 4.1 0.0 6.6 7 0 0 7 7 6 0 TFA2 Winged helix domain 2 Cas_DxTHG PF09455.10 KPA36131.1 - 3.2e-05 23.7 0.0 0.08 12.5 0.0 2.6 1 1 1 2 2 2 2 CRISPR-associated (Cas) DxTHG family CENP-O PF09496.10 KPA36131.1 - 4e-05 23.7 1.3 0.72 9.8 0.2 4.7 1 1 1 2 2 2 1 Cenp-O kinetochore centromere component TPR_6 PF13174.6 KPA36131.1 - 0.00025 21.5 5.0 80 4.2 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Mod_r PF07200.13 KPA36131.1 - 0.00074 19.6 9.7 0.89 9.6 0.1 4.8 2 1 0 4 4 4 1 Modifier of rudimentary (Mod(r)) protein RPN6_N PF18055.1 KPA36131.1 - 0.0023 18.3 1.5 56 4.1 0.1 5.0 2 1 4 6 6 6 0 26S proteasome regulatory subunit RPN6 N-terminal domain DEDD_Tnp_IS110 PF01548.17 KPA36131.1 - 0.0024 17.7 0.0 52 3.7 0.0 5.3 3 1 3 7 7 7 0 Transposase ATP-synt_ab PF00006.25 KPA36131.1 - 0.0028 17.4 0.1 17 5.0 0.0 4.8 1 1 4 6 6 6 0 ATP synthase alpha/beta family, nucleotide-binding domain NRBF2_MIT PF17169.4 KPA36131.1 - 0.0034 17.6 0.7 43 4.4 0.0 5.8 6 1 0 6 6 6 0 MIT domain of nuclear receptor-binding factor 2 FmiP_Thoc5 PF09766.9 KPA36131.1 - 0.0047 16.3 8.6 0.73 9.1 0.1 4.4 2 1 4 6 6 6 2 Fms-interacting protein/Thoc5 SMBP PF16785.5 KPA36131.1 - 0.0059 16.8 13.1 12 6.2 0.3 6.2 2 1 4 6 6 5 0 Small metal-binding protein DUF4407 PF14362.6 KPA36131.1 - 0.04 13.3 3.3 1 8.6 1.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) CHAD PF05235.14 KPA36131.1 - 0.043 13.8 18.0 1.1 9.2 5.5 4.5 1 1 2 3 3 3 0 CHAD domain DNA_pack_N PF02500.15 KPA36131.1 - 0.063 13.1 0.0 0.97 9.2 0.0 2.3 1 1 2 3 3 3 0 Probable DNA packing protein, N-terminus Imm53 PF15580.6 KPA36131.1 - 0.084 12.6 0.1 1.9e+02 1.9 0.0 4.9 5 1 1 6 6 6 0 Immunity protein 53 DUF5633 PF18656.1 KPA36131.1 - 0.14 12.0 15.9 26 4.8 0.1 5.6 6 0 0 6 6 6 0 Family of unknown function (DUF5633) Laminin_II PF06009.12 KPA36131.1 - 0.18 11.8 5.6 6.6 6.8 0.3 3.5 2 1 3 5 5 5 0 Laminin Domain II KASH_CCD PF14662.6 KPA36131.1 - 0.5 10.2 5.5 2 8.2 0.4 3.7 3 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH FTA4 PF13093.6 KPA36131.1 - 1 9.2 10.9 3.3 7.6 4.6 3.8 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CheZ PF04344.13 KPA36131.1 - 1.4 8.8 3.8 1e+02 2.7 0.0 4.0 2 1 2 5 5 5 0 Chemotaxis phosphatase, CheZ IFT57 PF10498.9 KPA36131.1 - 1.6 7.6 6.4 1.6 7.6 0.2 2.8 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 Phage_GP20 PF06810.11 KPA36131.1 - 2.2 8.1 8.4 18 5.1 0.1 4.8 2 1 4 6 6 6 0 Phage minor structural protein GP20 Occludin_ELL PF07303.13 KPA36131.1 - 3.6 8.4 4.5 1.3e+02 3.4 0.0 4.6 4 1 2 6 6 4 0 Occludin homology domain OrsD PF12013.8 KPA36132.1 - 3.5e-07 30.6 0.1 6.6e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_12 PF18658.1 KPA36132.1 - 0.15 11.7 0.1 0.37 10.4 0.1 1.6 2 0 0 2 2 2 0 Zinc-finger C2H2-type WSC PF01822.19 KPA36134.1 - 1.4e-12 47.6 9.0 1.4e-12 47.6 9.0 3.2 3 0 0 3 3 3 1 WSC domain Parecho_VpG PF06344.11 KPA36134.1 - 0.21 12.2 1.3 2.3e+02 2.8 0.0 3.9 3 0 0 3 3 3 0 Parechovirus Genome-linked protein HET PF06985.11 KPA36135.1 - 1e-13 51.9 0.0 4.8e-10 40.0 0.0 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KPA36136.1 - 5.1e-15 55.6 0.0 1.5e-14 54.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA36136.1 - 4.7e-08 32.6 0.0 3.5e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA36136.1 - 0.042 13.2 0.0 0.092 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like EcKinase PF02958.20 KPA36136.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_Tyr PF07714.17 KPA36137.1 - 8.6e-08 31.8 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KPA36137.1 - 0.00014 21.3 0.0 0.0019 17.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Isochorismatase PF00857.20 KPA36143.1 - 1.9e-13 50.9 0.1 3.8e-13 50.0 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family Alpha_TIF PF02232.15 KPA36143.1 - 0.077 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) p450 PF00067.22 KPA36145.1 - 9.3e-31 107.1 0.0 1.4e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.6 KPA36146.1 - 3.9e-21 75.1 0.5 1e-20 73.8 0.5 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Far-17a_AIG1 PF04750.14 KPA36146.1 - 0.0064 15.8 0.4 0.013 14.8 0.4 1.5 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DevR PF01905.16 KPA36146.1 - 0.23 10.5 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 Sulfotransfer_4 PF17784.1 KPA36147.1 - 6.2e-48 163.5 0.0 7.3e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPA36147.1 - 0.001 19.5 0.2 0.078 13.4 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family p450 PF00067.22 KPA36148.1 - 5.6e-36 124.3 0.0 6.9e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SF-assemblin PF06705.11 KPA36148.1 - 0.046 13.1 0.1 0.07 12.5 0.1 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin p450 PF00067.22 KPA36149.1 - 1e-15 57.5 0.0 1.2e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MethyTransf_Reg PF10119.9 KPA36149.1 - 0.055 14.2 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain V_ATPase_I PF01496.19 KPA36149.1 - 0.16 9.9 0.2 0.21 9.4 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_transf_64 PF09258.10 KPA36150.1 - 1e-51 175.6 0.0 1.4e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain TPT PF03151.16 KPA36151.1 - 1.1e-15 57.8 30.6 1.3e-15 57.6 30.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KPA36151.1 - 0.32 11.2 40.3 0.93 9.7 18.2 2.2 2 0 0 2 2 2 0 EamA-like transporter family EST1_DNA_bind PF10373.9 KPA36152.1 - 2.7e-14 53.3 0.0 6.8e-14 52.0 0.0 1.7 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain UCR_14kD PF02271.16 KPA36152.1 - 0.091 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit LRR19-TM PF15176.6 KPA36152.1 - 0.72 9.9 3.3 1.4 8.9 0.1 2.7 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain FANCF PF11107.8 KPA36153.1 - 0.0092 15.2 0.1 0.015 14.5 0.1 1.2 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) Endonuclease_1 PF04231.13 KPA36153.1 - 0.021 14.5 0.1 0.031 14.0 0.1 1.2 1 0 0 1 1 1 0 Endonuclease I Glyco_hydro_62 PF03664.13 KPA36154.1 - 4.2e-135 449.4 5.5 4.8e-135 449.2 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 HET PF06985.11 KPA36155.1 - 9.7e-18 64.9 0.0 2.8e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 KPA36156.1 - 5.9e-27 94.1 1.2 1e-26 93.3 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPA36156.1 - 1.3e-06 28.4 0.0 2.9e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Soc PF16855.5 KPA36156.1 - 0.077 13.5 0.1 0.31 11.6 0.1 2.0 1 0 0 1 1 1 0 Small outer capsid protein Amidase PF01425.21 KPA36157.1 - 2.4e-67 227.9 0.2 1.4e-66 225.3 0.2 2.0 1 1 0 1 1 1 1 Amidase Acetyltransf_1 PF00583.25 KPA36158.1 - 6e-07 29.7 0.1 1.1e-06 28.8 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA36158.1 - 5.1e-06 26.8 0.0 1.2e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA36158.1 - 0.00041 20.4 0.0 0.00063 19.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA36158.1 - 0.00085 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KPA36158.1 - 0.001 19.0 0.1 0.051 13.6 0.1 3.0 2 1 1 3 3 3 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KPA36158.1 - 0.014 15.5 0.0 0.052 13.7 0.0 1.9 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase EcKinase PF02958.20 KPA36160.1 - 7.7e-18 64.8 0.0 5.5e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 KPA36160.1 - 2.8e-10 40.6 0.0 1.7e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KPA36160.1 - 5.6e-09 35.4 0.0 7.5e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Acetyltransf_1 PF00583.25 KPA36161.1 - 2.1e-08 34.4 0.0 2.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA36161.1 - 2.8e-06 27.7 0.0 3.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA36161.1 - 0.00024 21.0 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 KPA36161.1 - 0.0086 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1688 PF07958.11 KPA36162.1 - 5.4e-169 562.4 0.0 6.1e-169 562.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) PALP PF00291.25 KPA36163.1 - 5.3e-64 216.4 0.1 7.1e-64 216.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 KPA36163.1 - 0.028 14.3 0.2 0.059 13.2 0.2 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DegT_DnrJ_EryC1 PF01041.17 KPA36163.1 - 0.071 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Rieske PF00355.26 KPA36165.1 - 6.3e-08 32.4 0.0 1.2e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KPA36165.1 - 1.1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain AMP-binding PF00501.28 KPA36168.1 - 4.6e-72 242.9 0.0 6.5e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KPA36168.1 - 2.1e-31 109.1 0.8 4.3e-22 78.4 0.3 3.2 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 KPA36168.1 - 2e-06 28.0 0.0 3.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF3237 PF11578.8 KPA36169.1 - 1.6e-32 112.4 0.0 2.1e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) MFS_1 PF07690.16 KPA36170.1 - 1.1e-26 93.6 26.5 1.1e-26 93.6 26.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA36170.1 - 4.1e-11 42.4 35.0 1.9e-10 40.2 35.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter PhrC_PhrF PF11131.8 KPA36170.1 - 0.42 10.2 2.2 14 5.3 0.1 3.3 2 0 0 2 2 2 0 Rap-phr extracellular signalling DUF4131 PF13567.6 KPA36170.1 - 0.83 9.3 7.3 0.33 10.6 1.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) SurE PF01975.17 KPA36172.1 - 2.2e-40 138.5 0.0 3e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Sugar_tr PF00083.24 KPA36173.1 - 3.2e-83 280.1 23.9 3.9e-83 279.8 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36173.1 - 7.7e-18 64.5 40.7 6.6e-14 51.6 16.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA36173.1 - 0.0017 17.3 7.9 0.0017 17.3 7.9 2.2 2 1 0 2 2 2 1 MFS_1 like family ABC2_membrane PF01061.24 KPA36175.1 - 6.8e-77 257.6 50.1 2.3e-43 148.1 20.4 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KPA36175.1 - 2.6e-41 141.4 0.1 4.7e-21 75.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KPA36175.1 - 2.4e-18 65.8 10.1 6.2e-17 61.3 0.0 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KPA36175.1 - 2.4e-09 36.8 27.4 4.9e-07 29.2 14.1 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KPA36175.1 - 1.1e-08 35.6 0.2 0.0001 22.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KPA36175.1 - 5.8e-06 25.9 0.2 0.18 11.2 0.0 3.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KPA36175.1 - 2.1e-05 24.5 0.4 0.00044 20.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KPA36175.1 - 0.0012 18.5 0.0 0.045 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPA36175.1 - 0.0013 18.5 0.1 0.48 10.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPA36175.1 - 0.0013 18.4 0.6 0.052 13.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KPA36175.1 - 0.0014 18.5 0.0 2 8.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KPA36175.1 - 0.0014 18.9 0.0 0.38 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KPA36175.1 - 0.004 16.5 0.0 0.34 10.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 KPA36175.1 - 0.0042 17.2 0.0 3.4 7.8 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KPA36175.1 - 0.006 16.3 0.1 2.2 8.0 0.0 3.3 4 0 0 4 4 3 1 IstB-like ATP binding protein NACHT PF05729.12 KPA36175.1 - 0.0067 16.4 0.1 0.41 10.5 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KPA36175.1 - 0.0069 16.9 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KPA36175.1 - 0.009 15.2 0.1 3.5 6.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.13 KPA36175.1 - 0.015 14.5 0.1 0.088 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KPA36175.1 - 0.015 15.1 0.0 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KPA36175.1 - 0.017 14.7 0.1 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KPA36175.1 - 0.017 15.5 0.1 17 5.9 0.0 3.1 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KPA36175.1 - 0.02 15.1 0.0 0.38 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KPA36175.1 - 0.02 15.0 0.0 0.24 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KPA36175.1 - 0.024 15.0 0.3 2.1 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain MASE2 PF05230.11 KPA36175.1 - 0.041 14.0 0.1 0.28 11.3 0.1 2.5 1 0 0 1 1 1 0 MASE2 domain TsaE PF02367.17 KPA36175.1 - 0.042 13.9 0.3 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KPA36175.1 - 0.067 13.6 0.0 8.7 6.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KPA36175.1 - 0.08 13.2 0.3 7.7 6.8 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KPA36175.1 - 0.11 12.4 0.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 KPA36175.1 - 0.12 11.7 0.1 5 6.4 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Septin PF00735.18 KPA36175.1 - 0.16 11.2 0.1 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.12 KPA36175.1 - 0.21 10.8 1.7 2.4 7.4 0.1 2.6 3 0 0 3 3 3 0 Zeta toxin Fungal_trans PF04082.18 KPA36176.1 - 3.2e-07 29.7 0.2 6.1e-07 28.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gpr1_Fun34_YaaH PF01184.19 KPA36177.1 - 2.2e-39 135.2 22.9 4.2e-39 134.3 22.9 1.3 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Acyl-CoA_dh_2 PF08028.11 KPA36177.1 - 3.5e-12 46.7 0.2 6.6e-12 45.8 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPA36177.1 - 9.1e-05 22.6 0.1 0.00044 20.4 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPA36177.1 - 0.0062 17.2 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KPA36177.1 - 0.13 12.4 0.4 0.39 10.9 0.4 1.7 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ADH_zinc_N PF00107.26 KPA36178.1 - 2.8e-08 33.8 0.0 6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA36178.1 - 0.0081 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ceramidase_alk PF04734.13 KPA36178.1 - 0.22 10.1 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal Bac_luciferase PF00296.20 KPA36179.1 - 7.4e-63 212.8 0.0 9e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ketoacyl-synt PF00109.26 KPA36180.1 - 2.5e-37 128.8 0.3 2.7e-37 128.7 0.3 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KPA36180.1 - 0.15 11.4 0.2 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Ferric_reduct PF01794.19 KPA36181.1 - 2.5e-21 76.1 15.7 5.4e-21 75.0 15.7 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPA36181.1 - 2.6e-08 34.1 0.1 0.0045 17.1 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KPA36181.1 - 0.00021 21.9 0.1 0.00086 19.9 0.1 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KPA36181.1 - 0.004 17.2 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain DUF1011 PF06237.12 KPA36181.1 - 0.17 12.3 3.1 0.13 12.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) DUF420 PF04238.12 KPA36181.1 - 0.32 11.3 15.9 0.6 10.4 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF420) NTase_sub_bind PF08780.11 KPA36183.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like PfkB PF00294.24 KPA36184.1 - 3.2e-56 190.9 0.5 3.7e-56 190.6 0.5 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KPA36184.1 - 0.0013 18.2 0.8 0.013 14.9 0.2 2.1 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase MFS_1 PF07690.16 KPA36185.1 - 1.1e-35 123.2 22.5 1.5e-35 122.8 22.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2157 PF09925.9 KPA36185.1 - 0.6 9.9 9.5 0.09 12.6 1.7 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) SKG6 PF08693.10 KPA36187.1 - 0.0058 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Phage_holin_2_4 PF16082.5 KPA36187.1 - 0.023 14.4 0.1 0.053 13.3 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like FixQ PF05545.11 KPA36187.1 - 0.024 14.6 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Gram_pos_anchor PF00746.21 KPA36187.1 - 0.04 13.9 1.3 0.093 12.7 0.4 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Mid2 PF04478.12 KPA36187.1 - 0.066 13.0 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF347 PF03988.12 KPA36187.1 - 0.084 13.1 0.5 0.084 13.1 0.5 1.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) ComP_DUS PF16732.5 KPA36188.1 - 0.12 13.3 0.7 0.23 12.4 0.7 1.5 1 0 0 1 1 1 0 Type IV minor pilin ComP, DNA uptake sequence receptor FAD_binding_4 PF01565.23 KPA36189.1 - 1.5e-12 47.5 0.0 2.3e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ERG4_ERG24 PF01222.17 KPA36190.1 - 5.4e-71 239.6 9.7 6.7e-71 239.3 9.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KPA36190.1 - 6.5e-06 25.8 0.9 1.3e-05 24.8 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KPA36190.1 - 0.00098 19.5 0.0 0.0027 18.1 0.0 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family MFS_1 PF07690.16 KPA36191.1 - 1.8e-13 50.1 11.6 2.1e-13 50.0 11.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA36191.1 - 3.5e-06 26.2 3.9 3.5e-06 26.2 3.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.18 KPA36192.1 - 9.6e-10 37.9 0.1 1.7e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pectate_lyase PF03211.13 KPA36193.1 - 1.6e-84 282.5 9.8 1.9e-84 282.3 9.8 1.0 1 0 0 1 1 1 1 Pectate lyase Carb_anhydrase PF00194.21 KPA36194.1 - 1.6e-30 106.5 0.0 2.9e-14 53.2 0.0 2.3 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Bac_rhamnosid_C PF17390.2 KPA36196.1 - 4.5e-10 39.2 0.3 1.3e-09 37.7 0.1 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 KPA36196.1 - 3.2e-07 29.9 0.3 8.2e-07 28.6 0.3 1.6 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Laminin_G_2 PF02210.24 KPA36196.1 - 0.0021 18.7 0.1 0.038 14.6 0.0 2.3 2 0 0 2 2 2 1 Laminin G domain DUF608 PF04685.13 KPA36196.1 - 0.028 13.6 0.8 0.045 12.9 0.8 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region DUF1080 PF06439.11 KPA36196.1 - 0.029 14.5 0.0 0.069 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) S4 PF01479.25 KPA36196.1 - 0.065 13.0 0.2 0.19 11.5 0.2 1.8 2 0 0 2 2 2 0 S4 domain Laminin_G_1 PF00054.23 KPA36196.1 - 0.075 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain Git3 PF11710.8 KPA36198.1 - 3.2e-17 63.0 11.5 6.7e-17 61.9 11.5 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 KPA36198.1 - 7.4e-09 35.2 10.2 2.7e-08 33.3 6.3 2.0 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 KPA36198.1 - 0.092 12.8 2.6 0.46 10.6 0.0 3.1 4 0 0 4 4 4 0 G protein-coupled glucose receptor regulating Gpa2 C-term Fzo_mitofusin PF04799.13 KPA36198.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 fzo-like conserved region CbiQ PF02361.16 KPA36198.1 - 0.32 10.6 7.6 0.11 12.1 4.6 1.7 1 1 1 2 2 2 0 Cobalt transport protein Stevor PF17410.2 KPA36198.1 - 8.2 5.9 9.2 0.18 11.3 1.0 2.0 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Zn_clus PF00172.18 KPA36199.1 - 0.00011 22.3 8.9 0.00011 22.3 8.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SlyX PF04102.12 KPA36199.1 - 0.42 11.3 3.7 0.44 11.2 1.6 2.2 2 0 0 2 2 2 0 SlyX NBP1 PF08537.10 KPA36199.1 - 0.5 9.7 5.7 0.83 9.0 5.7 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 LPP PF04728.13 KPA36199.1 - 0.89 10.0 3.6 23 5.5 0.5 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Glyco_hydro_43 PF04616.14 KPA36200.1 - 0.0021 17.4 1.7 0.0032 16.8 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 MetallophosN PF16371.5 KPA36200.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 N terminal of Calcineurin-like phosphoesterase NAD_binding_8 PF13450.6 KPA36201.1 - 5.6e-14 52.1 0.3 1.6e-13 50.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPA36201.1 - 3.6e-07 29.2 0.1 2.7e-06 26.3 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KPA36201.1 - 2.7e-06 26.7 0.3 3.8e-06 26.2 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA36201.1 - 9.5e-06 25.4 0.2 2.1e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KPA36201.1 - 6.9e-05 22.4 0.1 0.00012 21.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA36201.1 - 0.00024 20.4 0.0 0.0011 18.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA36201.1 - 0.00026 20.3 0.1 0.0004 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KPA36201.1 - 0.0084 16.6 0.4 0.019 15.5 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA36201.1 - 0.0096 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KPA36201.1 - 0.012 14.9 0.3 0.022 14.0 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA36201.1 - 0.054 13.5 1.2 0.093 12.7 0.2 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KPA36201.1 - 0.055 13.7 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain GMC_oxred_N PF00732.19 KPA36201.1 - 0.067 12.6 0.2 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 GMC oxidoreductase Lycopene_cycl PF05834.12 KPA36201.1 - 0.11 11.6 0.1 0.19 10.7 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Reprolysin_5 PF13688.6 KPA36202.1 - 0.0069 16.6 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M6 PF05547.11 KPA36202.1 - 0.01 14.2 2.3 0.033 12.5 0.1 2.2 2 0 0 2 2 2 0 Immune inhibitor A peptidase M6 Fungal_trans PF04082.18 KPA36203.1 - 0.0023 17.0 0.0 0.0058 15.7 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Arginase PF00491.21 KPA36204.1 - 4.4e-22 78.9 0.0 5.2e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family Fungal_trans_2 PF11951.8 KPA36205.1 - 1.4e-08 34.0 2.4 3.7e-07 29.3 0.8 2.5 2 1 0 2 2 2 2 Fungal specific transcription factor domain Haspin_kinase PF12330.8 KPA36205.1 - 0.048 12.6 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Transferase PF02458.15 KPA36206.1 - 7.1e-22 77.7 0.0 1.5e-21 76.6 0.0 1.5 1 1 0 1 1 1 1 Transferase family ADH_zinc_N PF00107.26 KPA36206.1 - 3.6e-17 62.6 0.2 8.4e-17 61.4 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA36206.1 - 1.6e-12 48.6 0.0 5.3e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA36206.1 - 3.1e-09 36.7 0.0 6.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_43 PF04616.14 KPA36207.1 - 1.1e-05 24.9 1.4 1.4e-05 24.5 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Ribonuclease_T2 PF00445.18 KPA36208.1 - 3.5e-34 118.6 0.7 4.8e-34 118.2 0.7 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Aldose_epim PF01263.20 KPA36209.1 - 0.02 14.2 0.0 0.023 14.0 0.0 1.0 1 0 0 1 1 1 0 Aldose 1-epimerase Abhydrolase_9_N PF15420.6 KPA36210.1 - 7.7 6.5 8.9 1.1 9.2 0.7 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Podoplanin PF05808.11 KPA36211.1 - 0.0005 20.2 0.7 0.0008 19.5 0.7 1.3 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 KPA36211.1 - 0.001 18.0 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4690 PF15756.5 KPA36211.1 - 0.0031 18.1 1.6 0.0067 17.0 1.6 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage DUF2207 PF09972.9 KPA36211.1 - 0.012 14.4 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rax2 PF12768.7 KPA36211.1 - 0.025 14.0 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2981 PF11200.8 KPA36211.1 - 0.17 11.6 0.2 0.21 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) CI-B14_5a PF07347.12 KPA36211.1 - 0.2 11.6 0.5 0.52 10.2 0.5 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF3295 PF11702.8 KPA36213.1 - 2.6e-134 449.3 37.8 8.4e-105 352.0 15.7 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KPA36213.1 - 1.5e-10 40.7 0.3 2.9e-10 39.8 0.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Myc_target_1 PF15179.6 KPA36213.1 - 3.7 7.4 11.1 2.7 7.9 3.2 2.6 2 0 0 2 2 2 0 Myc target protein 1 DZR PF12773.7 KPA36214.1 - 0.011 15.7 1.4 0.011 15.7 1.4 1.9 2 0 0 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.11 KPA36214.1 - 0.016 14.9 0.3 0.048 13.3 0.3 1.8 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-C2H2_6 PF13912.6 KPA36214.1 - 0.022 14.7 0.2 0.022 14.7 0.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KPA36214.1 - 0.095 13.6 15.0 0.29 12.1 1.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KPA36214.1 - 8.5 6.8 9.4 14 6.1 4.5 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Trypsin PF00089.26 KPA36217.1 - 2.7e-10 40.5 0.5 5.7e-10 39.4 0.5 1.5 1 1 0 1 1 1 1 Trypsin PAP2 PF01569.21 KPA36217.1 - 4.3e-08 33.0 10.8 7.7e-05 22.5 3.4 2.7 3 0 0 3 3 3 2 PAP2 superfamily Trypsin_2 PF13365.6 KPA36217.1 - 4.9e-07 30.8 0.0 9.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain TPPK_C PF12555.8 KPA36217.1 - 6 7.0 7.3 6.5 6.9 3.4 2.3 1 1 1 2 2 2 0 Thiamine pyrophosphokinase C terminal Peptidase_M99 PF17033.5 KPA36218.1 - 0.14 11.6 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Carboxypeptidase controlling helical cell shape catalytic Abhydrolase_1 PF00561.20 KPA36219.1 - 9.6e-20 71.3 0.0 1.4e-15 57.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KPA36219.1 - 1.1e-16 60.8 0.0 3.3e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein AMP-binding PF00501.28 KPA36220.1 - 1.3e-14 53.6 0.0 1.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 KPA36220.1 - 0.051 12.4 0.0 0.46 9.3 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter PBD PF00786.28 KPA36222.1 - 0.0017 18.7 1.1 0.0079 16.5 0.1 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain TPR_12 PF13424.6 KPA36223.1 - 9.3e-06 25.9 0.2 0.035 14.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPA36223.1 - 0.0026 18.2 2.3 0.019 15.5 0.0 3.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPA36223.1 - 0.0042 17.8 2.0 1.8 9.6 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KPA36223.1 - 0.015 15.4 0.1 4.2 7.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 KPA36223.1 - 0.024 14.9 0.1 0.056 13.7 0.1 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_10 PF13374.6 KPA36223.1 - 0.049 13.5 2.0 0.9 9.5 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPA36223.1 - 0.099 12.5 0.0 9.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KPA36223.1 - 0.15 11.4 0.0 0.36 10.2 0.0 1.6 1 1 1 2 2 2 0 MalT-like TPR region TPR_4 PF07721.14 KPA36223.1 - 0.41 11.4 4.4 4.1 8.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat APH PF01636.23 KPA36224.1 - 6.1e-08 32.9 0.3 1e-07 32.2 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Chi-conotoxin PF16981.5 KPA36224.1 - 0.16 12.2 1.2 0.42 10.9 0.7 2.0 2 0 0 2 2 2 0 chi-Conotoxin or t superfamily Epimerase PF01370.21 KPA36225.1 - 1.1e-07 31.5 0.2 3.8e-07 29.8 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KPA36225.1 - 1.8e-05 24.0 0.6 7.8e-05 21.9 0.1 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KPA36225.1 - 0.0022 17.2 1.8 0.19 10.9 0.1 2.3 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KPA36225.1 - 0.0092 15.0 1.2 0.1 11.6 0.9 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPA36225.1 - 0.025 13.7 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein NmrA PF05368.13 KPA36225.1 - 0.032 13.8 0.4 0.054 13.0 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family Ldh_1_N PF00056.23 KPA36225.1 - 0.1 12.7 0.4 0.24 11.5 0.3 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KPA36225.1 - 0.11 11.9 7.0 0.63 9.4 0.1 2.7 2 1 1 3 3 3 0 GDP-mannose 4,6 dehydratase DUF3632 PF12311.8 KPA36230.1 - 1.7e-22 80.7 0.0 3.9e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Clr5 PF14420.6 KPA36231.1 - 1.3e-09 38.1 1.5 2.4e-09 37.3 0.1 2.3 3 0 0 3 3 3 1 Clr5 domain MOSC PF03473.17 KPA36232.1 - 8.5e-23 80.8 0.0 1.2e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KPA36232.1 - 1.3e-11 44.5 0.0 2.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Lactamase_B PF00753.27 KPA36233.1 - 2.6e-05 24.3 0.1 9.2e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPA36233.1 - 0.019 14.5 0.2 0.046 13.2 0.2 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain BNR_2 PF13088.6 KPA36235.1 - 0.00014 21.3 0.6 0.48 9.7 0.1 2.3 1 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.20 KPA36235.1 - 0.00023 20.7 3.1 0.3 11.2 0.1 3.9 3 0 0 3 3 3 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KPA36235.1 - 0.003 16.4 2.6 0.088 11.6 3.7 3.0 2 1 0 2 2 2 1 Sortilin, neurotensin receptor 3, BTB PF00651.31 KPA36236.1 - 0.0011 19.2 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KPA36238.1 - 5.1e-05 23.5 2.6 5.1e-05 23.5 2.6 3.0 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KPA36238.1 - 0.0067 16.4 0.9 0.0067 16.4 0.9 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA36238.1 - 0.028 14.7 0.3 0.028 14.7 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KPA36238.1 - 0.034 15.0 1.8 0.034 15.0 1.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Zap1_zf2 PF18217.1 KPA36238.1 - 0.1 12.6 2.4 0.1 12.6 2.4 2.2 2 0 0 2 2 2 0 Zap1 zinc finger 2 zf-LYAR PF08790.11 KPA36238.1 - 0.23 11.4 0.6 0.23 11.4 0.6 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF2083 PF09856.9 KPA36238.1 - 0.38 10.6 6.0 2.9 7.7 0.3 2.6 1 1 1 2 2 2 0 Predicted transcriptional regulator (DUF2083) zf-H2C2_2 PF13465.6 KPA36238.1 - 2.9 8.5 9.7 2.7 8.6 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain GGDEF PF00990.21 KPA36242.1 - 0.055 13.2 0.4 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 Diguanylate cyclase, GGDEF domain Golgin_A5 PF09787.9 KPA36245.1 - 0.14 11.6 11.3 0.24 10.8 11.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3450 PF11932.8 KPA36245.1 - 0.31 10.3 3.7 0.48 9.7 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FapA PF03961.13 KPA36245.1 - 0.36 9.4 4.9 0.5 8.9 4.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Erp_C PF06780.11 KPA36245.1 - 0.43 10.6 4.2 0.91 9.5 4.2 1.5 1 0 0 1 1 1 0 Erp protein C-terminus UPF0242 PF06785.11 KPA36245.1 - 0.63 10.1 6.2 1 9.5 6.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 KPA36245.1 - 8.4 5.5 5.6 11 5.1 5.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Methyltransf_23 PF13489.6 KPA36247.1 - 0.00024 21.0 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain p450 PF00067.22 KPA36248.1 - 2.1e-52 178.5 0.0 2.6e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Exo_endo_phos_2 PF14529.6 KPA36249.1 - 8.6e-15 54.6 0.5 1.8e-14 53.6 0.5 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KPA36249.1 - 6.4e-06 25.9 1.9 8.5e-06 25.5 0.8 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family OrsD PF12013.8 KPA36250.1 - 4.9e-27 94.6 2.1 1.6e-26 93.0 2.1 2.0 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Cwf_Cwc_15 PF04889.12 KPA36250.1 - 2.8e-05 24.0 3.6 6.5e-05 22.8 3.6 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Helicase_C PF00271.31 KPA36250.1 - 0.00058 20.2 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RsbRD_N PF14361.6 KPA36250.1 - 1.9 9.2 6.2 0.73 10.6 0.7 3.0 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain SDA1 PF05285.12 KPA36250.1 - 4 6.8 6.1 7.2 5.9 6.1 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KPA36250.1 - 5.6 4.9 11.9 10 4.1 11.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KPA36250.1 - 5.7 6.0 12.3 11 5.1 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIA PF03153.13 KPA36250.1 - 8.7 6.2 10.1 1.3 8.9 5.6 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.18 KPA36251.1 - 1.1e-08 35.0 12.7 1.7e-08 34.4 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HIPIP PF01355.17 KPA36251.1 - 2.5 8.5 7.6 4.8 7.6 7.6 1.4 1 0 0 1 1 1 0 High potential iron-sulfur protein APH PF01636.23 KPA36252.1 - 5.5e-20 72.3 0.2 6.7e-20 72.0 0.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KPA36252.1 - 0.006 16.2 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KPA36252.1 - 0.0073 15.9 0.0 0.012 15.2 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KPA36252.1 - 0.061 12.5 0.0 0.54 9.4 0.0 2.0 1 1 0 1 1 1 0 Fructosamine kinase APH PF01636.23 KPA36253.1 - 1.9e-12 47.6 0.6 2.7e-12 47.1 0.6 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPA36253.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KPA36253.1 - 0.057 13.0 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family WSC PF01822.19 KPA36255.1 - 1.9e-05 24.8 2.0 2.6e-05 24.3 2.0 1.2 1 0 0 1 1 1 1 WSC domain CFEM PF05730.11 KPA36256.1 - 4.8e-07 29.8 2.7 8.6e-07 29.0 2.7 1.4 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.16 KPA36258.1 - 7.9e-25 87.5 32.6 7.9e-25 87.5 32.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA36258.1 - 2.2e-10 40.0 6.2 2.2e-10 40.0 6.2 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter p450 PF00067.22 KPA36259.1 - 2.5e-52 178.1 0.0 2.9e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CCDC24 PF15669.5 KPA36259.1 - 0.2 11.5 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family RTA1 PF04479.13 KPA36260.1 - 4.7e-64 215.8 10.9 6.4e-64 215.4 10.9 1.2 1 0 0 1 1 1 1 RTA1 like protein PalH PF08733.10 KPA36260.1 - 8.4 5.3 13.7 0.18 10.8 2.5 2.1 1 1 0 2 2 2 0 PalH/RIM21 Amb_V_allergen PF03913.13 KPA36261.1 - 7.9 6.5 20.2 1.7 8.7 5.3 3.7 4 0 0 4 4 4 0 Amb V Allergen CFEM PF05730.11 KPA36262.1 - 1.9e-06 27.9 10.8 1.9e-06 27.9 10.8 2.2 2 0 0 2 2 2 1 CFEM domain XG_FTase PF03254.13 KPA36262.1 - 0.8 8.3 3.3 1.1 7.9 3.3 1.1 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase DUF1348 PF07080.11 KPA36263.1 - 4.8e-62 207.6 6.2 5.5e-62 207.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KPA36263.1 - 1.1e-06 29.2 0.6 1.6e-06 28.7 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KPA36263.1 - 0.0041 17.5 0.1 0.0063 16.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Exo_endo_phos PF03372.23 KPA36267.1 - 4.2e-10 39.5 0.1 8.4e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HET PF06985.11 KPA36268.1 - 2.5e-22 79.8 0.2 4.7e-22 78.9 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KPA36269.1 - 1.1e-23 84.2 0.1 2e-23 83.4 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KPA36272.1 - 5.3e-46 155.1 0.7 1.2e-10 41.8 0.0 6.7 3 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA36272.1 - 4e-42 142.1 3.6 5.7e-07 30.0 0.0 9.7 4 3 6 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 KPA36272.1 - 6.9e-35 118.0 0.0 1.9e-05 24.9 0.0 11.7 10 1 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 KPA36272.1 - 7e-33 112.3 2.3 5.7e-08 32.9 0.0 8.9 6 3 1 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA36272.1 - 9.1e-30 99.4 4.7 0.012 16.1 0.0 14.0 15 0 0 15 15 15 6 Ankyrin repeat NB-ARC PF00931.22 KPA36272.1 - 0.0019 17.5 0.0 0.0043 16.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KPA36272.1 - 0.0087 16.3 0.0 0.034 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KPA36272.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain HU-CCDC81_bac_2 PF18175.1 KPA36272.1 - 0.17 11.8 0.6 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 Trypan_PARP PF05887.11 KPA36273.1 - 0.14 12.1 31.1 0.64 10.0 31.1 2.1 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3723 PF12520.8 KPA36275.1 - 0.0017 17.1 0.2 0.0025 16.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) DUF2034 PF10356.9 KPA36275.1 - 0.093 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) RsgA_GTPase PF03193.16 KPA36277.1 - 0.03 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KPA36277.1 - 0.12 12.1 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain CDH-cyt PF16010.5 KPA36278.1 - 9.4e-44 149.3 0.4 1.6e-43 148.6 0.4 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KPA36278.1 - 2.8e-26 92.6 0.0 6.7e-26 91.3 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA36278.1 - 6.2e-24 85.2 0.1 1.2e-23 84.3 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPA36278.1 - 4.1e-12 45.9 0.1 3.6e-05 23.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain CBM_1 PF00734.18 KPA36278.1 - 1.9e-07 30.9 9.1 5.6e-07 29.4 9.1 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain NAD_binding_8 PF13450.6 KPA36278.1 - 7.6e-07 29.3 0.0 5.4e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA36278.1 - 7.1e-06 25.8 0.2 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA36278.1 - 4e-05 24.1 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA36278.1 - 0.0004 19.7 0.2 0.00099 18.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA36278.1 - 0.0011 17.7 0.0 0.0017 17.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KPA36278.1 - 0.0026 16.9 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KPA36278.1 - 0.016 14.6 0.1 0.16 11.3 0.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA36278.1 - 0.016 14.5 0.2 0.19 10.9 0.4 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA36278.1 - 0.017 14.4 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DOMON PF03351.17 KPA36278.1 - 0.022 15.0 0.0 0.12 12.6 0.0 2.3 2 1 0 2 2 2 0 DOMON domain Thi4 PF01946.17 KPA36278.1 - 0.03 13.6 0.1 0.081 12.2 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Defensin_big PF14862.6 KPA36278.1 - 0.065 13.5 0.6 0.16 12.3 0.0 2.0 2 0 0 2 2 1 0 Big defensin Toxin_7 PF05980.12 KPA36278.1 - 0.79 10.0 2.8 1.9 8.8 2.8 1.7 1 0 0 1 1 1 0 Toxin 7 Methyltransf_23 PF13489.6 KPA36280.1 - 4.7e-17 62.3 0.0 6.4e-16 58.6 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA36280.1 - 6.7e-09 36.3 0.1 7e-08 33.1 0.0 2.8 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA36280.1 - 1.7e-08 34.4 0.6 2.3e-07 30.7 0.0 2.8 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA36280.1 - 0.00012 22.7 0.0 0.0034 18.1 0.0 3.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA36280.1 - 0.00033 21.2 0.0 0.0012 19.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KPA36280.1 - 0.003 17.3 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KPA36280.1 - 0.0047 16.5 0.0 0.04 13.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KPA36280.1 - 0.032 13.6 0.0 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KPA36280.1 - 0.092 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KPA36280.1 - 0.12 11.9 0.0 0.42 10.1 0.0 2.0 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KPA36280.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KPA36280.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Occludin_ELL PF07303.13 KPA36280.1 - 0.57 10.9 6.6 0.23 12.2 0.7 2.4 2 0 0 2 2 2 0 Occludin homology domain FapA PF03961.13 KPA36280.1 - 2.8 6.5 6.0 5.4 5.5 1.2 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 KPA36280.1 - 9.6 6.3 6.4 33 4.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ECH_1 PF00378.20 KPA36281.1 - 6.5e-19 68.2 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_C PF02911.18 KPA36281.1 - 4.4e-07 30.1 0.0 9.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain ECH_2 PF16113.5 KPA36281.1 - 0.001 18.6 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_N PF00551.19 KPA36281.1 - 0.012 15.4 0.0 0.19 11.4 0.0 2.5 1 1 0 1 1 1 0 Formyl transferase Msg2_C PF12373.8 KPA36281.1 - 0.14 11.6 0.9 0.33 10.4 0.9 1.5 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal Glyco_transf_8 PF01501.20 KPA36282.1 - 3.9e-14 52.8 0.4 9.6e-14 51.5 0.4 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KPA36282.1 - 1.6e-07 31.0 0.2 5.2e-07 29.3 0.1 1.7 2 0 0 2 2 2 1 Mannosyltransferase putative Aminotran_1_2 PF00155.21 KPA36283.1 - 6.5e-43 147.3 0.0 1.2e-42 146.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase PF00069.25 KPA36283.1 - 0.00029 20.3 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Beta_elim_lyase PF01212.21 KPA36283.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase NmrA PF05368.13 KPA36284.1 - 4.3e-20 72.3 0.0 4.7e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA36284.1 - 5.7e-13 49.2 0.0 8.9e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA36284.1 - 0.03 13.8 0.0 0.069 12.6 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NERD PF08378.11 KPA36284.1 - 0.13 12.7 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Nuclease-related domain Pectate_lyase PF03211.13 KPA36286.1 - 3.6e-83 278.1 9.5 4.3e-83 277.8 9.5 1.0 1 0 0 1 1 1 1 Pectate lyase adh_short PF00106.25 KPA36287.1 - 2.9e-10 39.9 0.0 3.7e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA36287.1 - 2.9e-09 36.8 0.0 3.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KPA36287.1 - 0.054 13.0 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Fungal_trans_2 PF11951.8 KPA36288.1 - 3.6e-30 105.0 0.7 1.4e-29 103.1 0.3 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain A_deaminase PF00962.22 KPA36289.1 - 1.6e-45 155.9 0.0 7.2e-45 153.7 0.0 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.11 KPA36289.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Sel1 PF08238.12 KPA36289.1 - 0.13 13.0 0.1 0.25 12.1 0.1 1.5 1 0 0 1 1 1 0 Sel1 repeat Bac_rhamnosid6H PF17389.2 KPA36290.1 - 5.9e-15 55.3 0.0 8.6e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KPA36290.1 - 0.00022 20.9 0.0 0.00062 19.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 KPA36290.1 - 0.00035 19.9 0.2 0.00056 19.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Trehalase PF01204.18 KPA36290.1 - 0.00043 19.2 0.1 0.0006 18.8 0.1 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_36 PF17167.4 KPA36290.1 - 0.0087 14.8 0.1 0.013 14.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Melibiase_2 PF16499.5 KPA36291.1 - 1.3e-53 182.0 0.8 2.6e-53 181.1 0.8 1.5 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KPA36291.1 - 2.1e-12 46.9 1.1 4.5e-12 45.9 1.1 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KPA36291.1 - 0.0044 16.0 0.2 0.011 14.7 0.0 1.7 2 0 0 2 2 2 1 Melibiase TLP1_add_C PF18313.1 KPA36292.1 - 1e-17 63.8 0.3 2.5e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain Thiolase_C PF02803.18 KPA36292.1 - 0.073 12.7 0.0 0.24 11.1 0.0 1.9 1 1 0 1 1 1 0 Thiolase, C-terminal domain Alpha-amylase PF00128.24 KPA36293.1 - 3.2e-113 378.7 0.0 4.3e-113 378.3 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KPA36293.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Sugar_tr PF00083.24 KPA36294.1 - 9.6e-86 288.4 19.6 1.1e-85 288.2 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36294.1 - 2.9e-18 65.9 27.8 2.2e-16 59.7 20.8 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA36294.1 - 1.1e-05 24.2 23.8 0.0021 16.7 2.7 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein Folate_carrier PF01770.18 KPA36294.1 - 0.0005 18.9 0.2 0.00098 18.0 0.2 1.4 1 0 0 1 1 1 1 Reduced folate carrier Romo1 PF10247.9 KPA36294.1 - 6.6 7.2 8.7 6.8 7.1 1.0 2.6 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Zn_clus PF00172.18 KPA36295.1 - 0.0062 16.6 8.8 0.01 16.0 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asparaginase PF00710.20 KPA36296.1 - 1.5e-50 171.4 1.0 2.1e-50 171.0 1.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KPA36296.1 - 3.4e-23 82.1 0.0 1.4e-22 80.1 0.0 2.0 2 1 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain HasA PF06438.12 KPA36296.1 - 0.062 12.9 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Heme-binding protein A (HasA) TPP_enzyme_M PF00205.22 KPA36296.1 - 0.11 12.3 0.0 1.1 9.0 0.0 2.5 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain DUF917 PF06032.12 KPA36298.1 - 1.3e-121 405.7 0.2 2.5e-121 404.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KPA36298.1 - 3.4e-29 101.8 0.1 7.7e-26 90.9 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KPA36298.1 - 1.9e-27 96.3 6.7 1e-22 80.7 0.3 3.6 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase MutL PF13941.6 KPA36298.1 - 4.8e-06 25.4 2.8 0.014 14.0 0.0 2.6 3 0 0 3 3 3 2 MutL protein StbA PF06406.11 KPA36298.1 - 0.00018 20.9 0.2 0.34 10.1 0.1 2.3 2 0 0 2 2 2 2 StbA protein FtsA PF14450.6 KPA36298.1 - 0.017 15.5 1.7 3 8.3 0.9 3.3 3 0 0 3 3 3 0 Cell division protein FtsA BcrAD_BadFG PF01869.20 KPA36298.1 - 1.4 8.3 8.5 0.096 12.2 0.7 2.6 2 1 1 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Transp_cyt_pur PF02133.15 KPA36299.1 - 7.6e-97 324.8 37.7 9.3e-97 324.6 37.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Gram_pos_anchor PF00746.21 KPA36299.1 - 0.89 9.6 7.7 0.24 11.4 1.0 3.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF4413 PF14372.6 KPA36300.1 - 0.0098 16.2 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) OrsD PF12013.8 KPA36301.1 - 2.8e-15 56.7 0.2 2.8e-15 56.7 0.2 2.7 3 0 0 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D Helicase_C PF00271.31 KPA36301.1 - 1.6e-09 38.1 1.7 2.2e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPA36301.1 - 7.5e-06 25.8 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase MDM10 PF12519.8 KPA36301.1 - 0.21 10.4 9.4 0.42 9.4 9.4 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 GREB1 PF15782.5 KPA36301.1 - 1.5 5.8 6.7 2.5 5.1 6.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 KPA36301.1 - 4.4 6.8 22.3 10 5.6 22.3 1.5 1 0 0 1 1 1 0 Spt20 family Lipase_3 PF01764.25 KPA36303.1 - 3.6e-21 75.5 0.0 5.7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 KPA36303.1 - 0.00038 20.5 0.0 0.00071 19.6 0.0 1.4 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.16 KPA36303.1 - 0.0015 18.4 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KPA36303.1 - 0.0025 18.4 0.0 0.0035 18.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KPA36303.1 - 0.0056 16.3 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Esterase PF00756.20 KPA36303.1 - 0.0077 15.9 0.0 0.018 14.7 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KPA36303.1 - 0.008 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 KPA36303.1 - 0.0081 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase FSH1 PF03959.13 KPA36303.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KPA36303.1 - 0.017 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KPA36303.1 - 0.055 13.6 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain YAcAr PF10686.9 KPA36303.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Peptidase_S28 PF05577.12 KPA36304.1 - 8.9e-34 117.0 0.5 1e-32 113.6 0.5 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Fungal_trans PF04082.18 KPA36305.1 - 2e-10 40.2 1.4 2.3e-10 39.9 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KPA36306.1 - 3.7e-28 98.5 32.7 3.7e-28 98.5 32.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA36306.1 - 1.2e-05 24.4 12.5 1.2e-05 24.4 12.5 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter ERGIC_N PF13850.6 KPA36306.1 - 0.0013 19.0 1.4 0.0098 16.2 0.1 2.4 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) APOBEC2 PF18772.1 KPA36310.1 - 0.18 11.9 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 APOBEC2 AAA_12 PF13087.6 KPA36311.1 - 4.3e-40 137.5 0.0 7.2e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPA36311.1 - 2.3e-23 83.3 0.1 4.6e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPA36311.1 - 7.5e-09 36.1 0.0 3.8e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain zf-CCCH_4 PF18044.1 KPA36311.1 - 2.6e-05 23.9 6.1 6.3e-05 22.7 6.1 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger AAA_30 PF13604.6 KPA36311.1 - 5.4e-05 23.0 0.0 0.00059 19.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain zf-CCCH PF00642.24 KPA36311.1 - 7.6e-05 22.5 4.0 0.00024 20.9 4.0 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2075 PF09848.9 KPA36311.1 - 0.00015 21.1 0.0 0.56 9.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf_CCCH_4 PF18345.1 KPA36311.1 - 0.00074 19.5 7.7 0.0021 18.1 7.7 1.9 1 0 0 1 1 1 1 Zinc finger domain Viral_helicase1 PF01443.18 KPA36311.1 - 0.066 12.9 0.1 3 7.5 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KPA36311.1 - 0.069 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KPA36311.1 - 0.14 12.5 0.1 0.43 10.9 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane PF01061.24 KPA36312.1 - 1.4e-78 263.1 64.4 1e-44 152.5 19.8 3.0 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KPA36312.1 - 1.8e-37 127.1 2.3 1.2e-29 102.0 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KPA36312.1 - 3.8e-30 105.2 0.0 7.9e-14 52.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KPA36312.1 - 3.6e-12 46.7 0.4 3.6e-12 46.7 0.4 2.6 3 0 0 3 3 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KPA36312.1 - 1.4e-10 40.9 38.1 1.7e-07 30.7 10.6 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KPA36312.1 - 4.9e-06 26.6 0.1 2.6e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KPA36312.1 - 0.0097 15.5 0.2 2.2 7.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA36312.1 - 0.022 15.2 0.8 3.5 8.0 0.0 3.2 3 0 0 3 3 2 0 AAA ATPase domain AAA_29 PF13555.6 KPA36312.1 - 0.037 13.8 0.1 1.6 8.5 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KPA36312.1 - 0.037 14.1 0.0 10 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KPA36312.1 - 0.054 14.0 0.0 0.23 12.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KPA36312.1 - 0.055 13.6 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pantoate_ligase PF02569.15 KPA36312.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase AAA_21 PF13304.6 KPA36312.1 - 0.13 12.0 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KPA36312.1 - 0.18 11.7 0.0 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Cpn10 PF00166.21 KPA36312.1 - 0.98 9.5 2.8 0.66 10.1 0.7 1.8 2 0 0 2 2 1 0 Chaperonin 10 Kd subunit p450 PF00067.22 KPA36314.1 - 5e-27 94.8 0.0 6.1e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Condensation PF00668.20 KPA36315.1 - 9.1e-82 275.1 0.0 1.9e-29 102.6 0.0 3.9 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 KPA36315.1 - 1.1e-24 86.8 0.0 4.1e-24 85.0 0.0 1.9 2 1 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 KPA36315.1 - 9.6e-11 41.9 2.4 0.0047 17.2 0.3 4.1 3 0 0 3 3 3 3 Phosphopantetheine attachment site CENP-Q PF13094.6 KPA36316.1 - 0.046 13.9 8.3 0.06 13.6 8.3 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ribonucleas_3_3 PF14622.6 KPA36317.1 - 0.00019 21.6 0.0 0.00026 21.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KPA36317.1 - 0.00033 21.2 0.2 0.0043 17.7 0.2 2.1 1 1 0 1 1 1 1 Ribonuclease III domain SPICE PF15678.5 KPA36317.1 - 0.1 12.0 0.1 0.11 11.8 0.1 1.0 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression Cupin_2 PF07883.11 KPA36318.1 - 3.3e-14 52.4 0.3 5e-14 51.8 0.3 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KPA36318.1 - 4.7e-10 39.5 0.1 6.9e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KPA36318.1 - 9.3e-05 22.1 0.1 0.00021 20.9 0.1 1.6 1 1 0 1 1 1 1 Cupin EutQ PF06249.12 KPA36318.1 - 0.00018 21.3 0.0 0.00036 20.3 0.0 1.4 1 1 0 1 1 1 1 Ethanolamine utilisation protein EutQ MannoseP_isomer PF01050.18 KPA36318.1 - 0.0012 18.7 0.0 0.0017 18.3 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_7 PF12973.7 KPA36318.1 - 0.0026 17.6 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 ChrR Cupin-like domain DMSP_lyase PF16867.5 KPA36318.1 - 0.003 17.2 0.0 0.0036 17.0 0.0 1.1 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase DUF2840 PF11000.8 KPA36318.1 - 0.0057 16.5 0.0 0.0074 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2840) Cupin_3 PF05899.12 KPA36318.1 - 0.011 15.4 0.1 0.019 14.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Ectoine_synth PF06339.12 KPA36318.1 - 0.02 15.1 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Ectoine synthase Auxin_BP PF02041.16 KPA36318.1 - 0.068 12.8 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein ARD PF03079.14 KPA36318.1 - 0.096 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Fungal_trans PF04082.18 KPA36319.1 - 2.3e-17 62.9 0.4 7.2e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain FliC PF12445.8 KPA36320.1 - 0.2 12.0 5.7 0.41 11.0 5.7 1.6 1 1 0 1 1 1 0 Flagellin protein SnoaL_2 PF12680.7 KPA36321.1 - 0.00011 22.8 0.0 0.00013 22.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain HATPase_c PF02518.26 KPA36322.1 - 7.3e-22 78.0 0.1 2.4e-21 76.3 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPA36322.1 - 1.1e-21 77.1 0.1 2.4e-20 72.8 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KPA36322.1 - 4.3e-12 45.9 0.0 1e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KPA36322.1 - 6.4e-06 26.8 0.0 3.1e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 KPA36322.1 - 0.035 14.4 0.0 1.7 9.0 0.0 3.0 3 1 0 3 3 3 0 GAF domain HATPase_c_3 PF13589.6 KPA36322.1 - 0.06 13.2 0.0 0.22 11.3 0.0 2.0 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KPA36322.1 - 0.12 12.3 0.2 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Glyoxalase PF00903.25 KPA36323.1 - 4e-10 40.0 0.0 9.4e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KPA36323.1 - 4.2e-07 30.2 0.0 6.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KPA36323.1 - 0.00051 20.2 0.0 0.0034 17.5 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KPA36323.1 - 0.043 14.6 0.0 0.12 13.2 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain F-box-like PF12937.7 KPA36324.1 - 3.2e-08 33.4 0.2 7.8e-08 32.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA36324.1 - 6.9e-05 22.6 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain Mito_carr PF00153.27 KPA36325.1 - 3.2e-51 171.2 9.0 4e-17 61.9 0.3 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KPA36325.1 - 6.8 7.1 13.0 6.4 7.2 5.1 3.5 2 2 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Fungal_trans PF04082.18 KPA36326.1 - 2.4e-23 82.5 0.2 4.8e-23 81.5 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA36326.1 - 8e-06 25.9 2.6 1.6e-05 24.9 2.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SlyX PF04102.12 KPA36326.1 - 1.2 9.8 7.4 0.1 13.3 0.9 2.6 3 0 0 3 3 3 0 SlyX PrpF PF04303.13 KPA36327.1 - 1.9e-90 303.5 0.4 3.9e-83 279.5 0.1 2.0 2 0 0 2 2 2 2 PrpF protein FAR1 PF03101.15 KPA36328.1 - 2.9e-05 24.7 0.0 5.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain MULE PF10551.9 KPA36328.1 - 0.0045 17.4 0.0 0.026 14.9 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain HTH_28 PF13518.6 KPA36329.1 - 8.3e-05 22.6 0.3 0.00014 21.9 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KPA36329.1 - 0.00038 20.1 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KPA36329.1 - 0.013 16.1 1.9 0.13 12.9 1.4 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 KPA36329.1 - 0.017 15.4 0.1 0.021 15.1 0.1 1.2 1 0 0 1 1 1 0 Transposase LZ_Tnp_IS481 PF13011.6 KPA36329.1 - 0.018 15.5 0.2 0.023 15.2 0.2 1.2 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 KPA36329.1 - 0.025 14.3 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_16 PF13191.6 KPA36330.1 - 1.1e-07 32.4 0.0 3.9e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA36330.1 - 2.8e-07 30.9 0.1 2e-06 28.1 0.0 2.2 2 1 1 3 3 3 1 AAA domain NACHT PF05729.12 KPA36330.1 - 6.6e-07 29.4 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KPA36330.1 - 0.0031 17.4 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Abhydrolase_6 PF12697.7 KPA36330.1 - 0.0044 17.6 0.0 0.008 16.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KPA36330.1 - 0.012 15.4 0.0 0.046 13.4 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein LCAT PF02450.15 KPA36330.1 - 0.021 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase AAA PF00004.29 KPA36330.1 - 0.03 14.8 0.0 0.15 12.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KPA36330.1 - 0.071 12.3 0.0 0.22 10.6 0.0 1.8 3 0 0 3 3 3 0 NB-ARC domain AAA_18 PF13238.6 KPA36330.1 - 0.08 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KPA36330.1 - 0.081 12.8 0.5 14 5.5 0.1 3.6 3 1 0 4 4 4 0 NTPase Init_tRNA_PT PF04179.12 KPA36330.1 - 0.094 13.0 0.1 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 Rit1 DUSP-like domain AAA_30 PF13604.6 KPA36330.1 - 0.17 11.6 0.1 0.39 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain PIR PF00399.19 KPA36331.1 - 1.1e-05 24.8 7.2 0.033 13.8 1.7 2.8 2 0 0 2 2 2 2 Yeast PIR protein repeat LIDHydrolase PF10230.9 KPA36332.1 - 0.0012 18.4 0.0 0.0015 18.2 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KPA36332.1 - 0.0088 16.7 0.1 0.009 16.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family OrsD PF12013.8 KPA36333.1 - 1.5e-15 57.6 0.0 3.4e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D FOXP-CC PF16159.5 KPA36333.1 - 0.0044 17.6 1.0 0.014 16.0 1.0 1.9 1 0 0 1 1 1 1 FOXP coiled-coil domain AF-4 PF05110.13 KPA36333.1 - 0.011 13.9 19.0 0.015 13.4 19.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein BUD22 PF09073.10 KPA36333.1 - 0.023 14.1 4.4 0.049 13.0 4.4 1.5 1 1 0 1 1 1 0 BUD22 NESP55 PF06390.12 KPA36333.1 - 0.029 14.0 6.3 0.061 12.9 6.3 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 KPA36333.1 - 0.97 9.4 8.5 1.8 8.5 8.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_phi PF04931.13 KPA36333.1 - 1 7.4 5.3 1.5 6.8 5.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Serglycin PF04360.12 KPA36333.1 - 1.2 9.1 4.2 49 3.8 0.0 2.3 2 0 0 2 2 2 0 Serglycin DUF515 PF04415.12 KPA36333.1 - 2.7 6.3 8.3 4 5.7 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CDC45 PF02724.14 KPA36333.1 - 4.1 5.6 5.6 6.8 4.9 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein FAD_binding_3 PF01494.19 KPA36334.1 - 2.2e-18 66.6 0.0 2.9e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA36334.1 - 3.3e-10 40.1 0.1 8e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA36334.1 - 9e-07 28.4 0.0 0.02 14.2 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA36334.1 - 0.00099 19.3 0.1 0.0021 18.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPA36334.1 - 0.017 15.6 0.1 0.72 10.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KPA36334.1 - 0.05 13.2 0.0 0.15 11.7 0.0 1.8 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Imm32 PF15566.6 KPA36334.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 32 TrkA_N PF02254.18 KPA36334.1 - 0.085 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glyoxalase PF00903.25 KPA36334.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Hydrophobin_2 PF06766.11 KPA36335.1 - 2.3e-23 81.9 9.7 2.8e-23 81.6 9.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CFEM PF05730.11 KPA36336.1 - 8.9e-10 38.5 3.9 1.8e-09 37.5 3.9 1.6 1 0 0 1 1 1 1 CFEM domain Csm1_N PF18504.1 KPA36337.1 - 0.01 16.1 7.2 0.47 10.8 4.3 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF2570 PF10828.8 KPA36337.1 - 0.03 14.1 2.7 1 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DUF4858 PF16150.5 KPA36337.1 - 0.1 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4858) O-antigen_lig PF13425.6 KPA36337.1 - 0.24 10.2 0.2 0.3 9.8 0.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Med21 PF11221.8 KPA36337.1 - 0.35 11.1 3.8 0.88 9.8 3.8 1.6 1 0 0 1 1 1 0 Subunit 21 of Mediator complex PTS_IIA PF02255.16 KPA36338.1 - 2.8 8.1 5.8 0.53 10.4 0.6 2.1 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit ADH_zinc_N PF00107.26 KPA36340.1 - 1.4e-15 57.4 0.0 1.1e-12 48.1 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA36340.1 - 3.4e-15 55.9 0.1 5.3e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KPA36340.1 - 2.1e-06 27.2 0.2 3.7e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KPA36340.1 - 1.7e-05 24.3 0.0 3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KPA36340.1 - 0.005 17.1 0.0 0.0091 16.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain PALP PF00291.25 KPA36340.1 - 0.0086 15.5 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PglD_N PF17836.1 KPA36340.1 - 0.02 15.5 0.0 0.038 14.6 0.0 1.5 1 0 0 1 1 1 0 PglD N-terminal domain NAD_binding_2 PF03446.15 KPA36340.1 - 0.025 14.8 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KPA36340.1 - 0.041 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KPA36340.1 - 0.043 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 KPA36340.1 - 0.083 13.4 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain Shikimate_DH PF01488.20 KPA36340.1 - 0.087 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_1 PF00561.20 KPA36341.1 - 4e-18 66.0 0.1 6.1e-18 65.4 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA36341.1 - 3.5e-13 50.7 3.4 7.8e-13 49.5 3.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA36341.1 - 1.1e-11 44.5 0.0 1.6e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KPA36341.1 - 0.00039 20.3 0.0 0.003 17.4 0.0 2.3 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KPA36341.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 KPA36341.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family bZIP_1 PF00170.21 KPA36343.1 - 0.00053 20.0 7.9 0.00086 19.4 7.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor Takusan PF04822.13 KPA36343.1 - 0.013 15.4 1.3 0.024 14.5 0.6 1.8 1 1 0 1 1 1 0 Takusan ABC_tran_Xtn PF12848.7 KPA36343.1 - 0.024 14.7 4.0 0.037 14.0 4.0 1.2 1 0 0 1 1 1 0 ABC transporter RP-C_C PF11800.8 KPA36343.1 - 0.095 12.8 0.8 0.15 12.1 0.8 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region TMF_TATA_bd PF12325.8 KPA36343.1 - 0.2 11.9 4.1 0.3 11.3 4.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cutinase PF01083.22 KPA36345.1 - 6.4e-42 143.5 0.0 7.4e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KPA36345.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 KPA36345.1 - 0.022 14.6 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 KPA36345.1 - 0.075 12.6 0.0 0.091 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PE-PPE PF08237.11 KPA36345.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 PE-PPE domain FAD_binding_3 PF01494.19 KPA36346.1 - 2.2e-07 30.5 0.0 4.7e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DUF1877 PF08974.10 KPA36346.1 - 0.054 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) Cation_ATPase_C PF00689.21 KPA36349.1 - 1.1e-41 142.5 11.8 1.1e-41 142.5 11.8 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KPA36349.1 - 1.6e-36 125.5 0.1 1.6e-36 125.5 0.1 3.1 5 0 0 5 5 5 1 E1-E2 ATPase Cation_ATPase PF13246.6 KPA36349.1 - 1.5e-16 60.2 0.0 4.8e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPA36349.1 - 2.1e-14 54.3 0.9 1e-13 52.1 0.9 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPA36349.1 - 9.6e-09 34.8 0.1 5.2e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPA36349.1 - 0.0044 16.8 0.2 0.0077 16.0 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2976 PF11190.8 KPA36349.1 - 0.45 10.3 4.5 3.6 7.5 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) IQCJ-SCHIP1 PF15157.6 KPA36349.1 - 1 9.2 2.9 3.3 7.6 0.0 2.6 3 0 0 3 3 3 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Ank_2 PF12796.7 KPA36350.1 - 7.8e-17 61.6 0.0 0.00037 21.0 0.0 5.3 3 3 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA36350.1 - 3.8e-11 43.3 0.1 0.0038 17.8 0.0 5.9 6 3 1 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA36350.1 - 1.2e-10 41.4 0.4 0.11 12.8 0.0 5.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KPA36350.1 - 4.3e-09 36.4 2.2 1.2 9.7 0.0 6.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 KPA36350.1 - 1e-08 34.7 3.3 0.21 12.3 0.2 7.7 8 0 0 8 8 8 1 Ankyrin repeat FA_hydroxylase PF04116.13 KPA36351.1 - 6.5e-22 78.3 11.1 6.5e-22 78.3 11.1 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily BBE PF08031.12 KPA36352.1 - 1.3e-07 31.6 1.1 2.6e-07 30.6 1.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Syntaxin_2 PF14523.6 KPA36355.1 - 6.4 7.2 8.8 1.1 9.6 1.8 2.8 3 0 0 3 3 3 0 Syntaxin-like protein Aldo_ket_red PF00248.21 KPA36357.1 - 4.4e-39 134.4 0.0 1.3e-38 132.9 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family HSP70 PF00012.20 KPA36359.1 - 2.8e-09 35.7 0.0 4.6e-08 31.7 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KPA36359.1 - 0.048 12.5 0.0 0.093 11.5 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein HNH_2 PF13391.6 KPA36360.1 - 4.9e-08 33.0 0.4 1.4e-07 31.5 0.1 2.0 2 0 0 2 2 2 1 HNH endonuclease Glyco_hydro_7 PF00840.20 KPA36361.1 - 8.7e-144 479.5 8.2 1e-143 479.2 8.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Abhydrolase_1 PF00561.20 KPA36362.1 - 1.1e-07 31.8 0.1 3.2e-07 30.3 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA36362.1 - 2.6e-05 24.9 0.0 3.9e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 KPA36362.1 - 0.0036 16.4 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.16 KPA36362.1 - 0.035 13.9 1.0 0.39 10.5 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase P-mevalo_kinase PF04275.14 KPA36363.1 - 3.5e-22 78.5 0.0 8.1e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Phosphomevalonate kinase FAD_binding_4 PF01565.23 KPA36363.1 - 1.5e-15 57.1 4.1 3.2e-15 56.1 4.1 1.6 1 0 0 1 1 1 1 FAD binding domain RrnaAD PF00398.20 KPA36363.1 - 0.015 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Sigma54_activat PF00158.26 KPA36363.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 KPA36363.1 - 0.067 12.2 0.0 4.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 KPA36363.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain BBE PF08031.12 KPA36363.1 - 0.084 13.0 0.0 0.32 11.1 0.0 2.0 1 0 0 1 1 1 0 Berberine and berberine like IstB_IS21 PF01695.17 KPA36363.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KPA36363.1 - 0.14 11.7 0.1 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Cupin_2 PF07883.11 KPA36364.1 - 3e-17 62.1 0.2 4.4e-17 61.6 0.2 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KPA36364.1 - 0.013 15.4 0.1 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain FAA_hydrolase PF01557.18 KPA36365.1 - 4e-60 203.2 0.0 5.2e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Zn_clus PF00172.18 KPA36366.1 - 5.9e-08 32.7 7.7 1.1e-07 31.8 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_2 PF00328.22 KPA36367.1 - 4.7e-05 22.9 0.0 0.0064 15.9 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-C2H2 PF00096.26 KPA36368.1 - 3.4e-11 42.9 23.9 0.00033 20.9 0.6 5.9 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA36368.1 - 4.2e-07 30.2 24.9 0.036 14.9 0.3 5.9 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA36368.1 - 3.6e-06 27.1 26.4 0.022 15.0 0.3 6.0 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPA36368.1 - 0.012 16.0 19.3 2.3 8.7 0.1 5.9 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KPA36368.1 - 0.013 15.7 0.4 0.013 15.7 0.4 3.9 2 1 3 5 5 5 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KPA36368.1 - 0.096 13.0 25.4 0.14 12.5 8.4 3.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.14 KPA36368.1 - 0.11 12.3 2.6 0.17 11.8 0.2 2.5 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2HE PF16278.5 KPA36368.1 - 0.12 12.8 0.2 0.12 12.8 0.2 3.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF678 PF05077.12 KPA36368.1 - 0.33 11.1 1.6 2.5 8.3 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF678) zf-C2H2_8 PF15909.5 KPA36368.1 - 2.6 8.4 13.2 4.2 7.7 2.4 3.1 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-RING_7 PF02591.15 KPA36368.1 - 5 7.4 9.1 8.9 6.6 0.1 3.2 3 0 0 3 3 2 0 C4-type zinc ribbon domain HypA PF01155.19 KPA36368.1 - 7.2 6.7 15.7 1.8e+04 -4.4 15.7 3.4 1 1 0 1 1 0 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2 PF00096.26 KPA36369.1 - 0.028 14.8 3.1 0.3 11.6 0.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type NOA36 PF06524.12 KPA36369.1 - 7.9 5.7 9.6 5.3 6.3 6.5 1.9 2 0 0 2 2 2 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KPA36369.1 - 9.6 5.9 7.8 14 5.3 7.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Methyltransf_25 PF13649.6 KPA36371.1 - 0.017 15.8 0.0 0.048 14.4 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain NAD_binding_8 PF13450.6 KPA36372.1 - 4.1e-14 52.6 0.0 9.1e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA36372.1 - 0.002 17.8 0.0 0.0055 16.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KPA36372.1 - 0.0078 15.5 0.1 8.5 5.5 0.0 3.6 3 1 1 4 4 4 2 Flavin containing amine oxidoreductase DUF2834 PF11196.8 KPA36373.1 - 7.9e-09 35.8 15.3 0.00022 21.5 0.2 4.0 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) MerC PF03203.14 KPA36373.1 - 2.6 8.5 15.7 5.9 7.4 4.0 3.3 2 1 1 3 3 3 0 MerC mercury resistance protein NUDIX PF00293.28 KPA36375.1 - 3.5e-18 65.9 0.0 4.8e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KPA36375.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain PLDc_2 PF13091.6 KPA36379.1 - 2.7e-06 27.3 0.2 0.00059 19.7 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PP_kinase_C PF13090.6 KPA36379.1 - 0.14 11.7 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 OCD_Mu_crystall PF02423.15 KPA36380.1 - 2.1e-17 63.1 0.0 7e-17 61.3 0.0 1.8 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KPA36380.1 - 1.4e-09 38.2 0.0 6e-09 36.1 0.0 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KPA36380.1 - 0.029 14.6 0.0 0.062 13.6 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 KPA36380.1 - 0.03 14.3 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 KPA36380.1 - 0.075 13.9 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Staph_opine_DH PF10100.9 KPA36380.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase Bmp PF02608.14 KPA36382.1 - 0.0028 16.7 0.1 0.0034 16.4 0.1 1.1 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like HET PF06985.11 KPA36383.1 - 1e-23 84.3 0.0 1.4e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KPA36384.1 - 3.5e-07 29.5 0.4 6.3e-07 28.7 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 KPA36385.1 - 8.5e-26 90.0 6.2 1.8e-25 89.0 6.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA36385.1 - 2.5e-17 63.1 0.3 3.9e-17 62.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA36385.1 - 0.0026 18.8 0.0 0.0057 17.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KPA36385.1 - 0.04 13.6 0.2 0.072 12.8 0.2 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NmrA PF05368.13 KPA36387.1 - 8.3e-16 58.2 0.0 1.1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA36387.1 - 3.5e-10 40.1 0.0 7.6e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Amidohydro_1 PF01979.20 KPA36388.1 - 3.7e-32 112.0 0.3 1.5e-21 77.1 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KPA36388.1 - 1.4e-16 61.1 0.5 7.5e-10 38.9 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Pkinase PF00069.25 KPA36389.1 - 7.3e-20 71.4 0.0 6.7e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA36389.1 - 2.8e-07 30.1 0.0 0.0015 17.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_48 PF02011.15 KPA36389.1 - 0.037 12.6 0.0 0.056 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 Asp PF00026.23 KPA36390.1 - 1.6e-13 50.8 0.2 2e-13 50.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA36390.1 - 0.0015 18.8 0.2 0.21 11.8 0.0 2.2 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp PF00026.23 KPA36391.1 - 2.1e-05 24.1 0.1 3.2e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Semialdhyde_dh PF01118.24 KPA36392.1 - 0.02 15.3 0.0 0.031 14.7 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KPA36392.1 - 0.04 13.8 0.0 0.053 13.4 0.0 1.3 1 1 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPA36392.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 KPA36393.1 - 4.1e-34 118.1 0.0 5.4e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA36393.1 - 3.3e-16 59.6 0.9 7.4e-13 48.9 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA36393.1 - 2.6e-07 30.5 0.6 0.1 12.2 0.2 3.7 3 1 1 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA36393.1 - 3.1e-07 30.0 0.0 8.3e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA36393.1 - 1.3e-05 25.3 0.5 3.2 7.7 0.0 4.2 3 1 1 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KPA36393.1 - 3e-05 23.1 0.1 0.47 9.2 0.1 3.1 3 0 0 3 3 3 2 Tryptophan halogenase K_oxygenase PF13434.6 KPA36393.1 - 7.8e-05 22.0 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPA36393.1 - 0.00086 19.5 0.1 0.79 10.0 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DUF1188 PF06690.11 KPA36393.1 - 0.0038 16.8 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) Lycopene_cycl PF05834.12 KPA36393.1 - 0.013 14.5 0.3 0.32 10.0 0.1 2.7 2 1 1 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KPA36393.1 - 0.017 15.5 0.0 1.4 9.4 0.0 2.6 3 0 0 3 3 3 0 Putative NAD(P)-binding TrkA_N PF02254.18 KPA36393.1 - 0.018 15.3 0.2 0.59 10.4 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 KPA36393.1 - 0.046 12.9 0.2 2.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Thi4 family Glyco_transf_54 PF04666.13 KPA36394.1 - 2.1e-15 56.3 0.0 2.4e-14 52.9 0.1 2.3 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.17 KPA36394.1 - 0.28 11.0 0.9 0.43 10.4 0.1 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Acetyltransf_1 PF00583.25 KPA36395.1 - 2.9e-10 40.4 0.0 3.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA36395.1 - 7.7e-10 39.1 0.0 1.2e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA36395.1 - 4e-09 36.5 0.1 5e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA36395.1 - 0.00047 20.2 0.0 0.00073 19.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DAO PF01266.24 KPA36397.1 - 1e-35 124.0 0.1 1.3e-35 123.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA36397.1 - 4.4e-07 30.0 1.0 1e-06 28.9 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPA36397.1 - 5.3e-06 26.0 3.9 5e-05 22.8 2.9 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPA36397.1 - 6.8e-06 25.4 0.3 1.1e-05 24.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA36397.1 - 1.5e-05 24.4 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA36397.1 - 0.00012 21.4 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KPA36397.1 - 0.00013 21.4 0.1 0.00022 20.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KPA36397.1 - 0.0017 17.6 0.0 0.0042 16.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA36397.1 - 0.0089 15.2 1.8 0.031 13.4 0.6 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KPA36397.1 - 0.011 14.5 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.24 KPA36397.1 - 0.015 14.6 0.2 0.028 13.7 0.2 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KPA36397.1 - 0.15 12.6 1.2 0.27 11.8 0.3 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA36397.1 - 0.16 11.0 0.2 0.79 8.7 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein WD40 PF00400.32 KPA36398.1 - 3.9e-15 56.0 8.1 0.00022 21.9 0.1 5.3 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA36398.1 - 0.0012 19.1 0.0 9.9 6.5 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA36398.1 - 0.012 14.6 0.9 0.6 9.0 0.0 3.0 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KPA36398.1 - 0.03 13.0 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KPA36398.1 - 0.085 12.9 0.0 11 6.1 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 KPA36399.1 - 1.2e-12 48.2 11.7 0.00012 22.8 0.3 6.9 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA36399.1 - 8e-08 32.5 1.0 0.46 10.8 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KPA36399.1 - 0.0097 15.8 1.1 14 5.8 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Dehydratase_MU PF02288.15 KPA36399.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Dehydratase medium subunit IKI3 PF04762.12 KPA36399.1 - 0.25 9.3 0.1 0.43 8.5 0.1 1.3 1 0 0 1 1 1 0 IKI3 family ADH_zinc_N PF00107.26 KPA36400.1 - 5.3e-08 32.9 0.0 1.8e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA36400.1 - 1e-07 33.1 0.0 2e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA36400.1 - 6.5e-05 22.8 0.0 0.00037 20.3 0.0 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Macoilin PF09726.9 KPA36401.1 - 8.7 4.8 12.2 9.8 4.6 12.2 1.1 1 0 0 1 1 1 0 Macoilin family Phospholip_A2_3 PF09056.11 KPA36402.1 - 8.5e-44 148.7 0.2 1.1e-43 148.4 0.2 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 TraV PF09676.10 KPA36402.1 - 0.0025 18.8 0.0 0.0046 17.9 0.0 1.4 1 0 0 1 1 1 1 Type IV conjugative transfer system lipoprotein (TraV) PBP PF01161.20 KPA36403.1 - 2.5e-19 69.9 0.7 3.5e-19 69.4 0.7 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pectate_lyase PF03211.13 KPA36404.1 - 1.4e-63 214.2 1.8 1.8e-63 213.8 1.8 1.1 1 0 0 1 1 1 1 Pectate lyase Pec_lyase_C PF00544.19 KPA36405.1 - 2.9e-44 151.2 1.7 4.1e-44 150.7 1.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KPA36405.1 - 2.4e-05 24.2 3.3 0.00078 19.3 3.3 2.2 1 1 0 1 1 1 1 Right handed beta helix region BIV_Env PF05858.12 KPA36405.1 - 0.058 11.6 0.3 0.075 11.2 0.3 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) HTHP PF11534.8 KPA36405.1 - 0.82 10.1 3.7 13 6.3 0.0 3.0 3 0 0 3 3 3 0 Hexameric tyrosine-coordinated heme protein (HTHP) CBM_4_9 PF02018.17 KPA36406.1 - 2.1e-06 28.0 0.4 5.9e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate binding domain PTPS PF01242.19 KPA36408.1 - 0.048 13.6 0.0 0.55 10.2 0.0 2.3 1 1 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase NAPRTase PF04095.16 KPA36408.1 - 0.062 12.9 2.0 0.22 11.1 0.1 2.1 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) family LMP PF04778.12 KPA36409.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 LMP repeated region ADH_N PF08240.12 KPA36410.1 - 7.6e-20 70.8 5.2 1.2e-19 70.2 5.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA36410.1 - 4.2e-16 59.1 0.0 7.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA36410.1 - 1.2e-07 32.8 0.0 1.9e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KPA36410.1 - 0.004 16.5 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KPA36410.1 - 0.035 13.5 0.1 0.068 12.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EHN PF06441.12 KPA36411.1 - 5.3e-31 107.2 4.9 2e-30 105.3 0.3 2.7 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPA36411.1 - 1.3e-14 54.5 0.0 4.5e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA36411.1 - 1.7e-05 25.6 0.1 8.5e-05 23.3 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family CdiI_2 PF18593.1 KPA36411.1 - 0.0046 17.6 0.1 0.13 12.9 0.0 3.1 3 0 0 3 3 3 1 CdiI immunity protein RecG_N PF17190.4 KPA36411.1 - 0.015 16.0 0.5 0.052 14.3 0.1 2.2 2 0 0 2 2 2 0 RecG N-terminal helical domain bZIP_1 PF00170.21 KPA36411.1 - 0.1 12.7 4.3 0.24 11.5 4.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor PcrB PF01884.17 KPA36412.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 PcrB family p450 PF00067.22 KPA36413.1 - 1.4e-64 218.6 0.0 1.9e-64 218.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5583 PF17821.1 KPA36414.1 - 0.074 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5583) Ribonuclease PF00545.20 KPA36414.1 - 0.12 13.2 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 ribonuclease Transferase PF02458.15 KPA36415.1 - 7.6e-09 34.7 0.0 9.3e-09 34.4 0.0 1.0 1 0 0 1 1 1 1 Transferase family WD40 PF00400.32 KPA36416.1 - 1.9e-31 107.6 6.5 2.3e-10 40.9 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA36416.1 - 1.5e-13 50.8 3.7 0.00026 21.2 0.1 3.9 2 1 2 4 4 3 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KPA36416.1 - 1.4e-09 38.1 0.0 4.1e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 KPA36416.1 - 7.5e-07 28.7 0.2 1.9e-06 27.4 0.2 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 KPA36416.1 - 5.4e-06 26.9 0.6 1.6e-05 25.4 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain Ge1_WD40 PF16529.5 KPA36416.1 - 2.7e-05 23.3 0.5 1.6 7.6 0.1 3.3 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KPA36416.1 - 0.00027 20.4 2.5 0.29 10.4 0.2 2.2 1 1 1 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 KPA36416.1 - 0.00048 18.8 0.4 0.0013 17.3 0.2 1.7 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.8 KPA36416.1 - 0.0012 17.7 2.4 0.5 8.9 0.2 2.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 JAKMIP_CC3 PF16034.5 KPA36416.1 - 0.016 15.2 1.1 0.036 14.0 1.1 1.5 1 0 0 1 1 1 0 JAKMIP CC3 domain AAA_13 PF13166.6 KPA36416.1 - 0.017 13.8 2.1 1.5 7.4 0.2 2.2 2 0 0 2 2 2 0 AAA domain OmpH PF03938.14 KPA36416.1 - 0.02 15.2 1.5 0.053 13.9 1.5 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NB-ARC PF00931.22 KPA36416.1 - 0.021 14.0 0.0 0.074 12.2 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Tmemb_cc2 PF10267.9 KPA36416.1 - 0.023 13.9 0.3 0.041 13.0 0.3 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein AAA PF00004.29 KPA36416.1 - 0.029 14.8 0.1 0.13 12.6 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KPA36416.1 - 0.031 14.8 0.0 0.093 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Robl_LC7 PF03259.17 KPA36416.1 - 0.034 13.9 0.9 20 5.0 0.0 4.0 5 0 0 5 5 4 0 Roadblock/LC7 domain DUF3450 PF11932.8 KPA36416.1 - 0.035 13.4 0.1 0.15 11.3 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PALB2_WD40 PF16756.5 KPA36416.1 - 0.059 12.3 1.7 0.18 10.7 0.6 2.2 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain AAA_30 PF13604.6 KPA36416.1 - 0.063 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain FH2 PF02181.23 KPA36416.1 - 0.065 12.3 4.7 0.13 11.3 1.6 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain KAP_NTPase PF07693.14 KPA36416.1 - 0.068 12.4 0.5 0.19 10.9 0.2 1.8 1 1 0 1 1 1 0 KAP family P-loop domain APS_kinase PF01583.20 KPA36416.1 - 0.091 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase BRO1 PF03097.18 KPA36416.1 - 0.098 11.4 1.2 0.16 10.7 1.2 1.3 1 0 0 1 1 1 0 BRO1-like domain Cep57_CLD PF14073.6 KPA36416.1 - 0.11 12.5 3.4 0.27 11.2 3.4 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Proteasome_A_N PF10584.9 KPA36416.1 - 0.17 11.6 0.3 29 4.4 0.0 2.9 3 0 0 3 3 2 0 Proteasome subunit A N-terminal signature CENP-H PF05837.12 KPA36416.1 - 0.17 12.3 1.5 0.41 11.1 1.5 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FliS PF02561.14 KPA36416.1 - 0.26 11.5 2.4 31 4.9 0.3 3.4 4 0 0 4 4 3 0 Flagellar protein FliS TPR_MLP1_2 PF07926.12 KPA36416.1 - 0.33 11.0 6.6 0.72 9.9 6.6 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 KPA36416.1 - 0.56 7.7 2.9 0.84 7.1 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sugar_tr PF00083.24 KPA36418.1 - 5.6e-76 256.2 23.6 6.4e-76 256.0 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36418.1 - 1.4e-19 70.3 61.7 5.1e-18 65.1 33.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily AmiS_UreI PF02293.15 KPA36418.1 - 0.061 13.3 20.7 0.097 12.7 13.1 3.2 2 1 0 2 2 2 0 AmiS/UreI family transporter TRI12 PF06609.13 KPA36418.1 - 0.14 10.5 6.8 0.019 13.4 1.6 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF2070 PF09843.9 KPA36418.1 - 0.83 7.9 11.0 0.016 13.5 4.4 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF4017 PF13209.6 KPA36418.1 - 2.9 7.9 6.7 4.9 7.2 4.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4017) Cyclase PF04199.13 KPA36419.1 - 2.4e-11 44.0 0.0 3.2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DUF3912 PF13051.6 KPA36419.1 - 0.04 14.2 0.1 0.074 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) DUF5490 PF17593.2 KPA36419.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5490) DUF2417 PF10329.9 KPA36420.1 - 0.12 11.8 5.9 0.24 10.8 5.9 1.5 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Popeye PF04831.13 KPA36420.1 - 3.1 8.0 6.8 9.1 6.5 6.8 1.7 1 0 0 1 1 1 0 Popeye protein conserved region MFS_1 PF07690.16 KPA36421.1 - 8.7e-33 113.7 24.4 8.7e-33 113.7 24.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KPA36421.1 - 7.1e-07 28.8 1.7 7.1e-07 28.8 1.7 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Trp_oprn_chp PF09534.10 KPA36421.1 - 0.00071 19.4 0.4 1.8 8.3 0.0 2.7 2 1 1 3 3 3 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Hydrophobin_2 PF06766.11 KPA36422.1 - 1.2e-23 82.8 9.4 1.5e-23 82.5 9.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Gly_transf_sug PF04488.15 KPA36423.1 - 4.1e-12 46.6 0.0 1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KPA36423.1 - 0.1 11.9 0.0 0.28 10.5 0.0 1.7 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein Acyl_transf_3 PF01757.22 KPA36424.1 - 6.2e-30 104.4 31.7 7.2e-30 104.2 31.7 1.1 1 0 0 1 1 1 1 Acyltransferase family CSG2 PF16965.5 KPA36424.1 - 0.012 14.6 0.2 0.024 13.6 0.2 1.5 1 0 0 1 1 1 0 Ceramide synthase regulator ketoacyl-synt PF00109.26 KPA36426.1 - 5.2e-64 216.3 0.0 9e-64 215.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KPA36426.1 - 2.6e-53 181.2 0.0 3.8e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KPA36426.1 - 2.7e-34 117.7 0.1 1e-32 112.6 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KPA36426.1 - 3.1e-30 105.8 0.0 1.6e-23 83.7 0.0 2.2 1 1 1 2 2 2 2 Acyl transferase domain Methyltransf_12 PF08242.12 KPA36426.1 - 6.9e-20 71.6 0.0 1.9e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KPA36426.1 - 4.4e-15 56.1 2.1 5.9e-13 49.2 2.1 2.7 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KPA36426.1 - 2.4e-12 47.0 0.0 4.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA36426.1 - 5.7e-12 46.2 0.0 2e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA36426.1 - 4.1e-11 42.9 0.0 9.1e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA36426.1 - 2.5e-09 37.7 0.0 7.2e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KPA36426.1 - 8.3e-06 25.6 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 KPA36426.1 - 0.00019 21.2 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 KPA36426.1 - 0.0019 17.6 0.2 0.0062 15.9 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KPA36426.1 - 0.042 13.7 0.3 0.11 12.3 0.3 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DREV PF05219.12 KPA36426.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.20 KPA36426.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase AXE1 PF05448.12 KPA36427.1 - 3.3e-14 52.3 0.0 4.8e-10 38.6 0.0 3.0 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KPA36427.1 - 7.8e-09 36.4 0.0 1e-08 36.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPA36427.1 - 9.7e-07 28.5 0.0 6.7e-05 22.5 0.0 2.1 1 1 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KPA36427.1 - 2.1e-06 27.5 0.0 7.2e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KPA36427.1 - 6.4e-05 22.3 0.0 0.00016 21.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA36427.1 - 0.00086 19.0 0.0 0.0021 17.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KPA36427.1 - 0.0027 17.7 0.0 0.018 15.0 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Lactamase_B PF00753.27 KPA36428.1 - 6.1e-16 59.0 0.1 1e-15 58.3 0.1 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TRAPPC-Trs85 PF12739.7 KPA36428.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Tautomerase_3 PF14832.6 KPA36429.1 - 1.7e-29 102.8 0.1 1.9e-29 102.7 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme NmrA PF05368.13 KPA36430.1 - 9.4e-27 94.1 0.0 1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA36430.1 - 3.4e-14 53.2 0.0 7.3e-14 52.1 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPA36430.1 - 1.1e-06 28.9 0.0 2.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 KPA36430.1 - 0.0013 19.4 0.1 0.0026 18.5 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 KPA36430.1 - 0.0015 18.7 0.1 0.0026 17.9 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Glu_dehyd_C PF16912.5 KPA36430.1 - 0.085 12.3 0.2 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus DUF5029 PF16432.5 KPA36430.1 - 0.11 12.0 0.1 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5029) Semialdhyde_dh PF01118.24 KPA36430.1 - 0.12 12.9 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KPA36431.1 - 2.6e-24 86.1 0.0 3.3e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA36431.1 - 3e-11 43.6 0.0 3.8e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA36431.1 - 0.0074 15.8 0.0 0.023 14.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KPA36431.1 - 0.035 14.4 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peripla_BP_4 PF13407.6 KPA36431.1 - 0.064 12.8 0.1 10 5.6 0.0 2.2 1 1 1 2 2 2 0 Periplasmic binding protein domain DUF3458_C PF17432.2 KPA36431.1 - 0.27 10.6 0.0 0.42 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats Dehydratase_hem PF13816.6 KPA36432.1 - 1.6e-106 356.2 0.0 1.9e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 KPA36432.1 - 1.3e-07 32.0 0.0 0.0042 17.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) GFA PF04828.14 KPA36433.1 - 2.1e-11 44.0 0.1 4.3e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme TF_Otx PF03529.13 KPA36433.1 - 0.093 13.1 2.2 0.17 12.3 2.2 1.4 1 0 0 1 1 1 0 Otx1 transcription factor Peroxidase_2 PF01328.17 KPA36434.1 - 1.2e-45 156.4 0.0 1.5e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 PAD_N PF08526.10 KPA36435.1 - 0.052 13.9 0.1 0.085 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain DUF5336 PF17270.2 KPA36435.1 - 0.074 12.7 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5336) PARP PF00644.20 KPA36436.1 - 2.7e-10 40.2 0.1 5.9e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KPA36436.1 - 3.6e-07 29.9 0.0 8.9e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Opiods_neuropep PF01160.18 KPA36436.1 - 0.18 11.9 1.1 0.39 10.8 0.4 2.0 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide DUF1752 PF08550.10 KPA36437.1 - 1.8e-07 30.9 0.2 3.6e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) 4HBT_2 PF13279.6 KPA36438.1 - 1.1e-13 51.7 0.0 1.5e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Mt_ATP-synt_D PF05873.12 KPA36438.1 - 0.016 15.1 3.9 0.024 14.5 3.9 1.4 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) ENT PF03735.14 KPA36438.1 - 0.079 13.0 1.0 8.1 6.6 0.1 2.2 1 1 1 2 2 2 0 ENT domain Endonuc_subdom PF09062.10 KPA36438.1 - 0.12 13.2 0.1 0.19 12.6 0.1 1.3 1 0 0 1 1 1 0 PI-PfuI Endonuclease subdomain adh_short PF00106.25 KPA36439.1 - 3.1e-23 82.2 0.6 4.6e-23 81.7 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA36439.1 - 3.8e-17 62.6 0.4 7.6e-17 61.6 0.4 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA36439.1 - 2.5e-09 37.3 0.1 4e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 KR domain ApbA PF02558.16 KPA36439.1 - 0.14 11.8 0.5 1.7 8.3 0.2 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KPA36439.1 - 0.2 11.5 0.2 0.36 10.7 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KPA36439.1 - 0.2 10.7 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Arrestin_C PF02752.22 KPA36440.1 - 0.00047 20.6 0.1 0.081 13.4 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Alpha-amylase PF00128.24 KPA36441.1 - 7e-113 377.6 0.4 1.2e-112 376.8 0.4 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KPA36441.1 - 0.0008 18.6 0.1 0.0037 16.4 0.1 1.9 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 KPA36441.1 - 0.0023 18.0 0.0 0.0057 16.7 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DUF3344 PF11824.8 KPA36441.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) Sugar_tr PF00083.24 KPA36442.1 - 1.2e-64 218.9 16.1 1.4e-64 218.7 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36442.1 - 5.4e-20 71.6 33.6 2.6e-11 43.0 6.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TOM6p PF15184.6 KPA36443.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog Ank_2 PF12796.7 KPA36444.1 - 1.3e-18 67.3 0.3 9.5e-05 22.9 0.0 6.5 5 2 3 8 8 8 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA36444.1 - 2.7e-16 58.0 1.2 0.0011 19.3 0.1 8.1 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 KPA36444.1 - 3.2e-12 46.7 0.3 0.0013 19.3 0.0 5.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA36444.1 - 4.4e-12 46.0 0.0 0.0032 17.8 0.0 6.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KPA36444.1 - 6.9e-12 45.3 0.6 0.0029 18.0 0.1 7.2 8 0 0 8 8 8 3 Ankyrin repeat WW PF00397.26 KPA36444.1 - 1.3e-10 41.1 0.1 3.2e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 WW domain F-box PF00646.33 KPA36445.1 - 0.0033 17.3 0.1 0.0096 15.8 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KPA36445.1 - 0.01 15.7 0.3 0.034 14.0 0.1 2.1 2 0 0 2 2 2 0 F-box-like GFO_IDH_MocA PF01408.22 KPA36446.1 - 9.8e-16 58.7 0.0 1.4e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Isochorismatase PF00857.20 KPA36447.1 - 1.7e-20 73.9 0.0 2.3e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Fungal_trans PF04082.18 KPA36448.1 - 1.6e-05 24.1 0.0 3.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNase PF00565.17 KPA36449.1 - 0.026 15.0 0.0 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 Staphylococcal nuclease homologue AAA PF00004.29 KPA36451.1 - 7.3e-36 123.5 0.1 5.6e-35 120.7 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA36451.1 - 2.8e-08 33.4 0.0 8.8e-08 31.8 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KPA36451.1 - 1e-07 32.3 0.2 0.049 13.9 0.0 3.9 2 1 2 4 4 4 2 AAA domain RuvB_N PF05496.12 KPA36451.1 - 3.7e-06 26.8 0.0 7.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPA36451.1 - 4.1e-06 27.3 0.1 0.00083 19.8 0.0 3.5 2 2 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KPA36451.1 - 1.7e-05 24.2 0.6 4.6e-05 22.8 0.1 1.9 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_33 PF13671.6 KPA36451.1 - 0.00018 21.7 0.0 0.00072 19.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KPA36451.1 - 0.00037 20.5 0.1 0.00082 19.4 0.1 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KPA36451.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 KPA36451.1 - 0.00076 19.5 0.0 0.0028 17.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KPA36451.1 - 0.0019 18.7 0.0 0.0067 17.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain Vps4_C PF09336.10 KPA36451.1 - 0.0044 17.0 0.1 0.025 14.6 0.0 2.4 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 KPA36451.1 - 0.0044 16.9 0.0 0.028 14.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KPA36451.1 - 0.0047 17.3 0.1 0.017 15.5 0.0 2.1 2 1 0 2 2 1 1 RNA helicase DUF815 PF05673.13 KPA36451.1 - 0.0048 16.1 0.0 0.012 14.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KPA36451.1 - 0.0051 15.9 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KPA36451.1 - 0.0061 16.8 0.2 0.084 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KPA36451.1 - 0.0074 16.1 0.3 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KPA36451.1 - 0.0093 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 KPA36451.1 - 0.01 15.8 0.4 0.99 9.3 0.0 3.5 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 KPA36451.1 - 0.013 15.3 0.2 0.66 9.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KPA36451.1 - 0.018 15.5 0.0 0.47 10.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 KPA36451.1 - 0.029 14.4 1.0 0.2 11.7 0.0 2.9 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.6 KPA36451.1 - 0.032 14.0 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 KPA36451.1 - 0.043 12.6 0.0 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Bac_DnaA PF00308.18 KPA36451.1 - 0.049 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein bMG5 PF17972.1 KPA36451.1 - 0.058 13.8 0.1 6.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG5 domain NB-ARC PF00931.22 KPA36451.1 - 0.072 12.3 0.2 0.33 10.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_2 PF07724.14 KPA36451.1 - 0.078 13.1 0.0 0.3 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Hydin_ADK PF17213.3 KPA36451.1 - 0.093 13.0 0.3 2.4 8.4 0.0 2.8 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain PhoH PF02562.16 KPA36451.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 KPA36451.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KPA36451.1 - 0.1 12.9 0.3 1.7 9.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KPA36451.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase HET PF06985.11 KPA36452.1 - 0.00061 20.2 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_18 PF00704.28 KPA36453.1 - 8.6e-63 212.9 0.9 1e-62 212.7 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DIOX_N PF14226.6 KPA36454.1 - 8.4e-20 71.7 0.0 1.5e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPA36454.1 - 1.3e-13 51.3 0.0 2.2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans_2 PF11951.8 KPA36455.1 - 8.9e-50 169.6 1.2 1.2e-49 169.2 1.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA36455.1 - 4.6e-09 36.3 5.9 8.7e-09 35.4 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF996 PF06195.13 KPA36456.1 - 0.89 9.8 8.3 5.3 7.3 7.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF996) DUF2206 PF09971.9 KPA36456.1 - 2.8 6.6 5.6 2.2 6.9 4.5 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2206) Patatin PF01734.22 KPA36458.1 - 9.9e-18 65.1 0.1 2.1e-16 60.7 0.1 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase Lipase_3 PF01764.25 KPA36458.1 - 0.051 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Glyco_trans_4_3 PF12000.8 KPA36458.1 - 0.06 13.0 0.0 0.65 9.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 4 group INCENP_N PF12178.8 KPA36459.1 - 0.082 12.9 0.7 0.18 11.9 0.7 1.6 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal NmrA PF05368.13 KPA36460.1 - 2.1e-05 24.2 0.0 2.9e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family FTA2 PF13095.6 KPA36464.1 - 3.5e-06 26.8 0.2 0.0002 21.1 0.2 2.7 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KPA36464.1 - 0.098 12.0 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain ResIII PF04851.15 KPA36466.1 - 0.0091 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPA36466.1 - 0.017 15.4 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Acetyltransf_3 PF13302.7 KPA36468.1 - 7.8e-06 26.6 0.3 2.7e-05 24.9 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Toxin_TOLIP PF00087.21 KPA36469.1 - 4.9 7.5 15.5 0.5 10.7 4.9 3.2 2 1 1 3 3 3 0 Snake toxin and toxin-like protein Fungal_trans PF04082.18 KPA36470.1 - 4e-21 75.2 2.8 5.9e-21 74.7 2.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA36470.1 - 5.6e-06 26.4 14.4 1.3e-05 25.2 14.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1148 PF06618.11 KPA36470.1 - 0.24 11.6 1.8 1.2 9.3 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1148) PRC2_HTH_1 PF18118.1 KPA36471.1 - 0.024 15.4 0.7 0.047 14.5 0.1 1.7 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain PMP22_Claudin PF00822.20 KPA36471.1 - 0.11 12.3 4.5 0.082 12.8 2.6 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF4064 PF13273.6 KPA36471.1 - 1.5 9.1 8.8 4.6 7.6 5.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Pyr_redox_3 PF13738.6 KPA36473.1 - 6.6e-13 48.6 0.0 1.4e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA36473.1 - 2.9e-11 43.1 0.0 1.5e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KPA36473.1 - 5.7e-09 34.9 0.0 3.5e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPA36473.1 - 8.5e-07 28.5 0.0 1.1e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA36473.1 - 0.00033 20.8 0.0 0.00095 19.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA36473.1 - 0.0051 16.4 0.1 3 7.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPA36473.1 - 0.0069 16.4 0.0 0.08 12.9 0.0 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 KPA36473.1 - 0.0084 15.4 0.0 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KPA36473.1 - 0.19 10.4 0.0 13 4.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Dimer_Tnp_hAT PF05699.14 KPA36476.1 - 2.1e-17 62.7 0.3 3.5e-17 62.0 0.3 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KPA36476.1 - 0.094 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) AAA_12 PF13087.6 KPA36477.1 - 3.6e-50 170.4 0.0 6.4e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPA36477.1 - 1.6e-48 165.8 2.4 2.5e-24 86.5 0.3 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KPA36477.1 - 1.3e-14 54.3 0.1 3.4e-13 49.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KPA36477.1 - 1.6e-14 54.5 0.9 8.6e-13 48.9 0.2 2.5 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 KPA36477.1 - 1.1e-07 31.8 0.1 3.1e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 KPA36477.1 - 1.5e-07 31.4 0.3 0.013 15.2 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KPA36477.1 - 2.2e-06 27.8 0.0 6.3e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KPA36477.1 - 4e-06 26.6 0.1 6.1e-05 22.7 0.1 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KPA36477.1 - 8.8e-06 25.6 0.1 2.3e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KPA36477.1 - 0.00013 22.3 0.2 0.0098 16.2 0.0 3.2 2 2 0 2 2 2 1 AAA domain PhoH PF02562.16 KPA36477.1 - 0.00013 21.5 0.2 0.0042 16.6 0.0 2.6 2 1 0 2 2 2 1 PhoH-like protein UvrD_C_2 PF13538.6 KPA36477.1 - 0.0035 17.1 0.1 0.018 14.8 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA PF00004.29 KPA36477.1 - 0.0057 17.1 0.0 0.034 14.6 0.0 2.4 2 1 1 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KPA36477.1 - 0.0063 16.5 0.0 0.024 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KPA36477.1 - 0.013 15.0 0.0 0.77 9.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KPA36477.1 - 0.016 15.6 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 KPA36477.1 - 0.029 13.6 0.7 0.082 12.1 0.1 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 KPA36477.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SBP_bac_11 PF13531.6 KPA36477.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein AAA_24 PF13479.6 KPA36477.1 - 0.15 11.8 0.0 0.38 10.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPA36477.1 - 0.16 12.4 0.0 0.6 10.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase FAD_binding_2 PF00890.24 KPA36479.1 - 7.6e-19 68.1 0.1 1e-18 67.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPA36481.1 - 2.6e-15 56.4 0.0 5.2e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPA36481.1 - 3.1e-07 29.8 0.4 4.1e-07 29.4 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA36481.1 - 8.1e-07 28.9 0.0 1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA36481.1 - 1.8e-06 26.9 0.4 2.4e-06 26.5 0.4 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KPA36481.1 - 1.4e-05 24.7 0.1 1.7e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KPA36481.1 - 5.8e-05 22.5 0.1 7.5e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KPA36481.1 - 9.9e-05 22.8 0.1 0.00018 22.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA36481.1 - 0.0001 21.6 0.0 0.00012 21.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA36481.1 - 0.0015 17.7 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KPA36481.1 - 0.0023 17.3 0.2 0.0031 16.8 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA36481.1 - 0.004 16.4 0.0 0.0061 15.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KPA36481.1 - 0.0041 17.1 0.1 0.0073 16.3 0.1 1.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding ApbA PF02558.16 KPA36481.1 - 0.012 15.3 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KPA36481.1 - 0.012 15.9 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain GMC_oxred_N PF00732.19 KPA36481.1 - 0.012 15.0 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase Amino_oxidase PF01593.24 KPA36481.1 - 0.014 14.8 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KPA36481.1 - 0.13 11.3 0.4 0.18 10.8 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AIG1 PF04548.16 KPA36482.1 - 1.4e-09 37.6 0.0 2.2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KPA36482.1 - 4.6e-08 33.1 0.0 9.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA36482.1 - 0.00031 20.7 0.1 0.00084 19.3 0.1 1.7 1 1 0 1 1 1 1 RsgA GTPase SRPRB PF09439.10 KPA36482.1 - 0.00057 19.4 0.0 0.0017 17.8 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Septin PF00735.18 KPA36482.1 - 0.0087 15.4 0.1 0.037 13.3 0.1 1.9 1 1 0 1 1 1 1 Septin AAA_16 PF13191.6 KPA36482.1 - 0.021 15.2 0.6 0.17 12.3 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 KPA36482.1 - 0.023 14.9 0.0 0.24 11.6 0.0 2.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KPA36482.1 - 0.024 14.7 1.7 0.45 10.5 0.1 2.5 1 1 0 2 2 2 0 Dynamin family DUF1651 PF07864.11 KPA36482.1 - 0.066 13.6 0.2 0.28 11.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1651) AAA_25 PF13481.6 KPA36482.1 - 0.076 12.6 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KPA36482.1 - 0.079 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 KPA36482.1 - 0.24 11.0 0.1 2.1 7.9 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 KPA36483.1 - 3e-09 37.0 0.2 6.4e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KPA36483.1 - 1.3e-07 31.2 0.2 5.3e-07 29.2 0.1 1.9 2 0 0 2 2 2 1 AIG1 family Septin PF00735.18 KPA36483.1 - 0.00012 21.5 0.8 0.00019 20.8 0.2 1.6 2 0 0 2 2 2 1 Septin SRPRB PF09439.10 KPA36483.1 - 0.0018 17.8 0.4 0.069 12.6 0.2 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KPA36483.1 - 0.0036 16.8 0.1 0.0061 16.1 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KPA36483.1 - 0.0045 16.6 3.0 0.73 9.3 3.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KPA36483.1 - 0.0049 16.9 4.8 0.089 12.9 0.1 3.1 2 2 1 3 3 3 1 Dynamin family CENP-F_leu_zip PF10473.9 KPA36483.1 - 0.0073 16.3 0.9 0.012 15.7 0.9 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SRP54 PF00448.22 KPA36483.1 - 0.011 15.4 0.1 0.025 14.2 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KPA36483.1 - 0.012 15.4 0.7 0.029 14.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KPA36483.1 - 0.016 15.1 0.8 0.051 13.5 0.8 1.8 1 1 0 1 1 1 0 RsgA GTPase Cast PF10174.9 KPA36483.1 - 0.018 13.3 0.9 0.023 12.9 0.9 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ATP_bind_1 PF03029.17 KPA36483.1 - 0.018 14.8 1.3 0.32 10.7 0.3 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ASD2 PF08687.11 KPA36483.1 - 0.022 14.3 0.3 0.031 13.8 0.3 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 AAA_28 PF13521.6 KPA36483.1 - 0.023 15.0 1.2 6.6 6.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KPA36483.1 - 0.027 14.4 0.1 0.053 13.5 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KPA36483.1 - 0.031 14.6 0.0 0.077 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4315 PF14193.6 KPA36483.1 - 0.08 13.0 0.7 0.08 13.0 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) ABC_tran PF00005.27 KPA36483.1 - 0.16 12.5 3.0 0.69 10.4 0.4 2.6 2 1 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KPA36483.1 - 0.23 11.6 1.4 0.45 10.7 1.4 2.0 1 1 0 1 1 1 0 AAA domain TolA_bind_tri PF16331.5 KPA36483.1 - 1.5 8.9 7.5 0.1 12.7 2.0 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF87 PF01935.17 KPA36483.1 - 2 8.5 5.2 0.47 10.5 0.6 2.2 3 1 0 3 3 3 0 Helicase HerA, central domain Acyl-CoA_dh_N PF02771.16 KPA36484.1 - 2.5e-20 73.2 0.0 3.4e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KPA36484.1 - 0.0075 16.4 0.1 0.02 15.1 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KPA36485.1 - 6.9e-32 110.7 2.5 8.2e-32 110.5 2.5 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KPA36485.1 - 2.4e-15 57.0 2.6 3.4e-15 56.5 2.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPA36485.1 - 0.0007 19.8 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF3106 PF11304.8 KPA36486.1 - 0.23 12.0 0.7 6.8 7.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Sugar_tr PF00083.24 KPA36488.1 - 4.4e-80 269.8 16.2 5.1e-80 269.6 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36488.1 - 9.6e-31 107.0 36.7 6.6e-30 104.2 17.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KPA36488.1 - 8.3e-05 21.1 10.1 0.00024 19.5 0.7 2.7 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KPA36488.1 - 0.00043 19.0 0.6 0.00043 19.0 0.6 2.7 2 2 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 KPA36489.1 - 1.2e-41 142.9 50.3 7.6e-40 136.9 41.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA36489.1 - 0.0001 21.3 30.5 0.00021 20.3 8.9 2.8 2 1 1 3 3 3 2 MFS_1 like family Romo1 PF10247.9 KPA36489.1 - 0.21 12.0 4.2 2.2 8.7 0.7 3.0 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Oxidored_FMN PF00724.20 KPA36491.1 - 9e-83 278.4 0.0 1.3e-82 277.8 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family COesterase PF00135.28 KPA36492.1 - 2.2e-87 294.1 0.0 2.7e-87 293.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA36492.1 - 2e-05 24.6 1.4 0.00018 21.5 1.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA36492.1 - 0.012 16.3 1.1 0.061 13.9 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPA36492.1 - 0.094 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.16 KPA36493.1 - 1.4e-30 106.4 41.5 9.1e-29 100.5 36.7 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3817 PF12823.7 KPA36493.1 - 0.028 15.2 1.6 0.028 15.2 1.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3817) Fungal_trans PF04082.18 KPA36494.1 - 1.2e-09 37.7 0.1 2.7e-09 36.5 0.1 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lin-8 PF03353.15 KPA36495.1 - 1.7 8.1 4.8 2.4 7.6 4.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Dimer_Tnp_hAT PF05699.14 KPA36496.1 - 5.8e-13 48.4 0.0 1.2e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Lipase_GDSL_2 PF13472.6 KPA36497.1 - 1e-11 45.6 0.2 1.3e-11 45.3 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA36497.1 - 3.1e-07 30.6 0.4 6.7e-07 29.5 0.4 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FMN_red PF03358.15 KPA36498.1 - 9.8e-24 83.9 0.0 1.6e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Methyltransf_31 PF13847.6 KPA36499.1 - 8.4e-25 87.3 0.0 1.2e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA36499.1 - 3.6e-18 66.0 0.0 7.4e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA36499.1 - 2.8e-16 59.9 0.0 5.2e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA36499.1 - 3.2e-13 49.6 0.2 6.1e-13 48.6 0.2 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KPA36499.1 - 2e-08 34.2 0.0 3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KPA36499.1 - 9.3e-08 31.8 0.9 1.6e-07 31.0 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KPA36499.1 - 2e-07 31.7 0.0 3.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KPA36499.1 - 6.3e-07 29.4 0.1 1.5e-06 28.2 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KPA36499.1 - 8.2e-05 22.2 0.1 0.00015 21.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KPA36499.1 - 0.00018 21.0 0.1 0.00067 19.2 0.1 1.9 2 0 0 2 2 2 1 Putative methyltransferase DOT1 PF08123.13 KPA36499.1 - 0.00046 19.8 0.2 0.001 18.6 0.2 1.6 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 KPA36499.1 - 0.001 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KPA36499.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.17 KPA36499.1 - 0.0032 16.7 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.19 KPA36499.1 - 0.0048 17.0 0.3 0.0082 16.3 0.3 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 KPA36499.1 - 0.019 14.8 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase UPF0020 PF01170.18 KPA36499.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 bZIP_1 PF00170.21 KPA36500.1 - 0.0011 19.0 4.5 0.0018 18.4 4.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor Sec2p PF06428.11 KPA36500.1 - 0.0012 18.8 0.6 0.0019 18.1 0.6 1.3 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p bZIP_2 PF07716.15 KPA36500.1 - 0.02 14.9 5.9 0.045 13.8 5.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper CCDC144C PF14915.6 KPA36500.1 - 0.028 13.5 1.7 0.038 13.1 1.7 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TRAF_BIRC3_bd PF16673.5 KPA36500.1 - 0.041 13.7 1.1 0.087 12.6 1.1 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain FlaC_arch PF05377.11 KPA36500.1 - 0.045 14.1 0.5 0.077 13.4 0.5 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 KPA36500.1 - 0.13 12.2 1.1 0.2 11.6 1.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit HR1 PF02185.16 KPA36500.1 - 0.47 10.6 4.1 0.24 11.5 2.1 1.5 2 0 0 2 2 2 0 Hr1 repeat Med7 PF05983.11 KPA36500.1 - 1.4 9.0 5.6 0.37 10.9 2.3 1.6 2 0 0 2 2 2 0 MED7 protein Endotoxin_C PF03944.14 KPA36501.1 - 0.06 13.7 2.8 0.087 13.2 0.6 2.2 1 1 1 2 2 2 0 delta endotoxin HTH_Tnp_Tc5 PF03221.16 KPA36503.1 - 0.00031 20.7 0.2 0.0013 18.8 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Polysacc_deac_2 PF04748.13 KPA36503.1 - 0.0028 16.9 0.6 0.024 13.8 0.0 2.2 2 0 0 2 2 2 1 Divergent polysaccharide deacetylase NES_C_h PF18208.1 KPA36503.1 - 0.031 14.5 0.2 0.067 13.5 0.2 1.5 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain MscS_TM PF12794.7 KPA36503.1 - 8.7 5.1 5.5 13 4.5 5.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RexA PF15969.5 KPA36504.1 - 0.057 13.0 0.0 0.073 12.6 0.0 1.1 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component Zip PF02535.22 KPA36505.1 - 8.6e-54 183.0 0.4 1.2e-53 182.5 0.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter TM2 PF05154.16 KPA36505.1 - 0.35 11.2 0.1 0.35 11.2 0.1 3.0 3 0 0 3 3 3 0 TM2 domain Exo_endo_phos PF03372.23 KPA36506.1 - 4.7e-11 42.6 0.2 2.8e-10 40.1 0.2 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family He_PIG PF05345.12 KPA36506.1 - 0.002 18.2 1.6 0.0087 16.2 1.6 2.2 1 0 0 1 1 1 1 Putative Ig domain Exo_endo_phos_2 PF14529.6 KPA36506.1 - 0.1 12.5 0.0 6.9 6.6 0.0 2.7 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase BACON PF13004.7 KPA36506.1 - 0.91 9.6 5.8 0.42 10.6 2.1 2.4 3 0 0 3 3 3 0 Putative binding domain, N-terminal Carbam_trans_C PF16861.5 KPA36508.1 - 0.011 15.3 0.1 0.015 14.8 0.1 1.4 1 1 0 1 1 1 0 Carbamoyltransferase C-terminus CCDC14 PF15254.6 KPA36508.1 - 0.12 11.0 0.7 0.17 10.5 0.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 JmjC PF02373.22 KPA36509.1 - 2.5e-06 27.9 0.1 7.1e-05 23.2 0.0 2.6 2 1 1 3 3 3 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KPA36509.1 - 0.0052 16.5 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_4 PF08007.12 KPA36509.1 - 0.037 13.5 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Gla PF00594.20 KPA36509.1 - 0.19 11.9 0.3 0.41 10.9 0.3 1.5 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Glyco_transf_34 PF05637.12 KPA36511.1 - 1.1e-07 31.9 0.2 4e-07 30.0 0.2 1.8 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 KPA36511.1 - 5e-06 26.6 2.7 1.1e-05 25.5 0.3 2.5 3 1 1 4 4 4 1 Nucleotide-diphospho-sugar transferase DUF1835 PF08874.10 KPA36511.1 - 0.08 13.2 0.1 0.19 12.0 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1835) BsuBI_PstI_RE_N PF17728.1 KPA36512.1 - 0.07 13.0 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease HTH domain ketoacyl-synt PF00109.26 KPA36513.1 - 1.1e-73 247.9 0.0 1.8e-73 247.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KPA36513.1 - 4e-47 160.9 0.0 6.4e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KPA36513.1 - 5.2e-43 147.8 0.2 9.8e-43 146.9 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KPA36513.1 - 1.9e-33 115.0 0.0 1.2e-32 112.4 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KPA36513.1 - 5.9e-21 75.1 0.0 2e-20 73.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA36513.1 - 4.6e-14 52.9 0.0 2e-13 50.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA36513.1 - 1.1e-12 48.1 0.0 3.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA36513.1 - 1.5e-12 47.6 0.0 3.2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA36513.1 - 4.9e-12 46.3 0.0 2.1e-11 44.3 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KPA36513.1 - 9.9e-11 42.1 0.0 2.9e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ubie_methyltran PF01209.18 KPA36513.1 - 2.1e-07 30.5 0.0 3.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KPA36513.1 - 2.2e-05 23.9 0.0 4.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 KPA36513.1 - 6.7e-05 22.7 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 KPA36513.1 - 0.0036 17.1 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF938) NodS PF05401.11 KPA36513.1 - 0.004 16.8 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 KPA36513.1 - 0.0063 15.8 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_33 PF10017.9 KPA36513.1 - 0.016 14.3 0.1 0.04 13.1 0.0 1.6 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent ACP_syn_III PF08545.10 KPA36513.1 - 0.13 12.1 0.5 1.2 9.1 0.5 2.5 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 KPA36514.1 - 7.5e-32 110.7 0.0 1.2e-18 67.2 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KPA36515.1 - 2.4e-20 72.7 0.0 3.4e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF996 PF06195.13 KPA36516.1 - 0.021 15.1 2.5 0.021 15.1 2.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF996) DUF1461 PF07314.11 KPA36516.1 - 0.042 13.7 0.2 0.042 13.7 0.2 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1461) Sex_peptide PF08138.11 KPA36516.1 - 0.085 13.0 0.3 0.3 11.3 0.1 2.0 2 0 0 2 2 2 0 Sex peptide (SP) family AA_permease_2 PF13520.6 KPA36517.1 - 3.9e-07 29.2 10.1 4.8e-07 28.9 10.1 1.1 1 0 0 1 1 1 1 Amino acid permease RexB PF15968.5 KPA36517.1 - 0.051 14.1 3.5 0.057 13.9 3.5 1.1 1 0 0 1 1 1 0 Membrane-anchored ion channel, Abi component Phage_holin_3_6 PF07332.11 KPA36517.1 - 3.1 7.9 8.4 0.32 11.1 2.0 1.9 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Aminotran_1_2 PF00155.21 KPA36518.1 - 7.7e-40 137.2 0.0 1e-39 136.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPA36518.1 - 1.2e-07 31.0 0.0 6.3e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KPA36518.1 - 1.9e-06 26.7 0.0 2.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KPA36518.1 - 6.1e-05 22.4 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.7 KPA36518.1 - 0.003 16.4 0.0 0.0038 16.1 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.13 KPA36518.1 - 0.056 12.3 0.9 0.16 10.8 0.5 1.9 2 1 0 2 2 2 0 Allinase Xrn1_D3 PF18194.1 KPA36518.1 - 0.062 13.4 0.1 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 Asp PF00026.23 KPA36519.1 - 3.4e-58 197.6 0.1 7.1e-58 196.5 0.1 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA36519.1 - 4.4e-09 36.8 0.3 9.4e-08 32.5 0.1 2.4 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KPA36519.1 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal GTP_EFTU PF00009.27 KPA36520.1 - 3.2e-58 196.5 0.1 5.1e-58 195.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KPA36520.1 - 1.5e-32 111.9 0.0 4e-32 110.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KPA36520.1 - 1.1e-31 108.7 0.0 2.5e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KPA36520.1 - 1.8e-23 82.3 0.0 4.1e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KPA36520.1 - 6.1e-13 49.0 0.0 1.4e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KPA36520.1 - 7e-06 25.9 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF442 PF04273.13 KPA36520.1 - 0.0073 16.4 0.4 0.12 12.4 0.1 3.0 3 0 0 3 3 3 1 Putative phosphatase (DUF442) AvrPtoB_bdg PF16847.5 KPA36520.1 - 0.088 13.3 0.0 2.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain Cytochrom_C_2 PF01322.20 KPA36520.1 - 0.11 13.4 1.8 2.6 8.9 0.4 2.7 2 0 0 2 2 2 0 Cytochrome C' Iso_dh PF00180.20 KPA36521.1 - 2e-98 329.8 0.0 3e-98 329.2 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TetR_C_31 PF17940.1 KPA36521.1 - 0.072 13.3 0.2 20 5.5 0.2 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1447 PF07288.11 KPA36521.1 - 0.19 11.8 0.4 0.53 10.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) Aa_trans PF01490.18 KPA36523.1 - 8.1e-27 94.0 36.6 1e-26 93.6 36.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HEV_ORF1 PF02444.16 KPA36523.1 - 0.12 12.9 1.4 0.26 11.9 1.4 1.5 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) CAAD PF14159.6 KPA36523.1 - 9.1 6.2 14.8 0.57 10.1 0.5 3.5 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase AAA_28 PF13521.6 KPA36524.1 - 6.6e-25 88.2 0.0 8.6e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KPA36524.1 - 0.00068 19.1 0.0 0.0045 16.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 KPA36524.1 - 0.00071 20.0 0.0 0.00092 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KPA36524.1 - 0.00078 19.6 0.0 0.0018 18.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KPA36524.1 - 0.0048 17.2 0.0 0.016 15.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain SRPRB PF09439.10 KPA36524.1 - 0.0084 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 KPA36524.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.9 1 1 0 1 1 1 0 RNA helicase dNK PF01712.19 KPA36524.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_18 PF13238.6 KPA36524.1 - 0.014 16.0 0.0 0.024 15.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KPA36524.1 - 0.015 15.7 0.0 0.075 13.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.6 KPA36524.1 - 0.022 13.6 0.1 0.38 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KPA36524.1 - 0.029 14.6 0.2 0.086 13.1 0.2 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KPA36524.1 - 0.037 14.1 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KPA36524.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 KPA36524.1 - 0.061 13.0 0.0 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain RdRP PF05183.12 KPA36525.1 - 4.1e-114 382.4 0.0 6.2e-114 381.8 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sugar_tr PF00083.24 KPA36526.1 - 2.5e-78 264.0 18.2 3e-78 263.7 18.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36526.1 - 1.4e-21 76.8 33.0 1.4e-14 53.8 12.4 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA36526.1 - 0.00033 19.6 2.4 0.00033 19.6 2.4 2.9 2 1 0 3 3 3 2 MFS_1 like family FAD_binding_3 PF01494.19 KPA36528.1 - 1.4e-09 37.7 0.1 1.7e-09 37.4 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA36528.1 - 3.4e-06 26.5 0.3 0.012 14.8 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA36528.1 - 1.6e-05 24.7 0.9 0.00018 21.2 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA36528.1 - 2.2e-05 24.9 0.2 0.0083 16.7 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA36528.1 - 2.8e-05 24.3 0.1 5.8e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPA36528.1 - 0.00061 19.3 0.2 0.00072 19.0 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA36528.1 - 0.00082 18.7 0.1 0.66 9.2 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA36528.1 - 0.0072 15.6 0.2 0.012 14.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KPA36528.1 - 0.0077 15.6 0.7 0.4 9.9 0.2 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KPA36528.1 - 0.035 13.2 0.6 0.049 12.7 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KPA36528.1 - 0.1 12.2 0.2 0.49 10.0 0.1 1.9 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA PLA2G12 PF06951.11 KPA36529.1 - 0.86 9.5 6.9 7.6 6.4 1.2 2.1 2 0 0 2 2 2 0 Group XII secretory phospholipase A2 precursor (PLA2G12) GMC_oxred_N PF00732.19 KPA36531.1 - 1.8e-61 208.1 0.0 2.6e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA36531.1 - 6.4e-31 107.8 0.0 1e-30 107.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPA36531.1 - 5.3e-09 35.6 0.1 0.00091 18.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPA36531.1 - 7.6e-06 25.7 0.1 0.014 15.0 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA36531.1 - 1.1e-05 24.9 0.1 0.15 11.3 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA36531.1 - 4.3e-05 23.6 0.1 0.00017 21.8 0.1 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPA36531.1 - 0.0012 18.0 0.1 0.0018 17.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KPA36531.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 KPA36531.1 - 0.046 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KPA36531.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein OsmC PF02566.19 KPA36532.1 - 8e-18 64.8 0.1 1.9e-17 63.5 0.1 1.6 1 1 1 2 2 2 1 OsmC-like protein CRAL_TRIO PF00650.20 KPA36533.1 - 1.6e-20 73.4 0.0 2.2e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain SLAC1 PF03595.17 KPA36534.1 - 3.8e-90 302.4 40.0 4.3e-90 302.3 40.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MttA_Hcf106 PF02416.16 KPA36535.1 - 0.0099 15.2 0.3 0.54 9.6 0.2 2.2 2 0 0 2 2 2 2 mttA/Hcf106 family Dynamin_N PF00350.23 KPA36536.1 - 4.1e-32 111.6 0.5 8.8e-32 110.5 0.2 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KPA36536.1 - 3.4e-20 72.5 0.1 1.3e-18 67.3 0.0 2.7 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KPA36536.1 - 3.2e-06 27.2 0.1 1.1e-05 25.5 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KPA36536.1 - 6e-05 23.1 0.0 0.00031 20.9 0.0 2.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain AAA_27 PF13514.6 KPA36536.1 - 0.00057 19.5 0.0 0.0035 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KPA36536.1 - 0.0084 15.9 1.2 0.034 13.8 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.18 KPA36536.1 - 0.0089 15.6 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 KPA36536.1 - 0.013 15.7 0.4 1 9.6 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase SWI-SNF_Ssr4 PF08549.10 KPA36536.1 - 7 5.1 8.3 15 4.1 8.3 1.5 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Lipoxygenase PF00305.19 KPA36537.1 - 2.7e-29 102.2 2.8 3.6e-29 101.7 2.8 1.1 1 0 0 1 1 1 1 Lipoxygenase Lipoxygenase PF00305.19 KPA36538.1 - 0.0027 16.2 0.0 0.0028 16.2 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase Glyco_hydro_5_C PF18564.1 KPA36541.1 - 2.7e-20 72.7 0.2 6.4e-20 71.5 0.2 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KPA36541.1 - 2.1e-13 50.4 0.0 3.1e-05 23.6 0.2 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) TauD PF02668.16 KPA36542.1 - 2.5e-29 102.9 0.0 4e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.16 KPA36543.1 - 9.7e-51 173.1 0.1 1.1e-50 173.0 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Hydrophobin_2 PF06766.11 KPA36544.1 - 1.5e-23 82.5 9.4 1.8e-23 82.2 9.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Chorion_3 PF05387.11 KPA36544.1 - 0.055 13.1 0.5 0.055 13.1 0.5 1.1 1 0 0 1 1 1 0 Chorion family 3 Amidase PF01425.21 KPA36545.1 - 4.2e-35 121.6 0.4 9e-35 120.5 0.1 1.6 2 0 0 2 2 2 1 Amidase HET PF06985.11 KPA36546.1 - 3.6e-21 76.0 1.0 2.2e-20 73.5 1.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lipase_GDSL_2 PF13472.6 KPA36547.1 - 9.2e-15 55.5 0.1 1.3e-14 55.0 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA36547.1 - 3.4e-05 23.9 1.1 0.00017 21.6 1.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Nudix_hydro PF18290.1 KPA36547.1 - 0.1 12.6 0.2 0.41 10.7 0.1 1.9 1 1 1 2 2 2 0 Nudix hydrolase domain Lipase_GDSL_3 PF14606.6 KPA36547.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family adh_short PF00106.25 KPA36548.1 - 1.2e-06 28.1 0.0 2.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA36548.1 - 0.00021 21.0 0.0 0.00063 19.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA36548.1 - 0.00051 20.0 0.1 0.0011 18.9 0.1 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA36548.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MOSC PF03473.17 KPA36549.1 - 3e-27 95.2 0.0 5.2e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KPA36549.1 - 1.4e-12 47.5 0.0 2.8e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain YoeB_toxin PF06769.14 KPA36549.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 YoeB-like toxin of bacterial type II toxin-antitoxin system Amino_oxidase PF01593.24 KPA36550.1 - 3.3e-12 46.4 0.0 2.7e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA36550.1 - 1.8e-09 37.7 0.1 4.1e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPA36550.1 - 2.2e-09 37.2 1.3 2.9e-09 36.8 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPA36550.1 - 1.6e-08 34.1 3.2 1.9e-07 30.6 2.8 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KPA36550.1 - 5.6e-08 32.4 0.4 5.4e-06 25.9 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA36550.1 - 9.6e-08 31.6 0.5 3.3e-06 26.5 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA36550.1 - 1.6e-07 31.8 3.6 9.4e-07 29.3 0.6 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA36550.1 - 6.8e-07 28.3 4.3 2.8e-06 26.3 2.2 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KPA36550.1 - 1.3e-06 28.3 0.0 6.7e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPA36550.1 - 4.3e-06 26.2 0.4 8.5e-06 25.2 0.4 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KPA36550.1 - 1e-05 24.8 0.6 1.6e-05 24.2 0.6 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KPA36550.1 - 0.00014 21.2 0.3 0.00022 20.6 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KPA36550.1 - 0.0053 15.8 0.7 0.19 10.8 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein IlvN PF07991.12 KPA36550.1 - 0.0065 16.1 0.3 0.015 14.9 0.3 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 KPA36550.1 - 0.0099 16.3 0.1 0.024 15.1 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding K_oxygenase PF13434.6 KPA36550.1 - 0.022 13.9 0.4 5.5 6.0 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Ribosomal_S9 PF00380.19 KPA36550.1 - 0.024 15.2 2.9 4.1 7.9 0.3 2.5 1 1 1 2 2 2 0 Ribosomal protein S9/S16 Trp_halogenase PF04820.14 KPA36550.1 - 0.024 13.5 0.3 0.036 12.9 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KPA36550.1 - 0.068 12.5 4.7 0.055 12.8 2.6 1.8 1 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KPA36550.1 - 0.073 12.9 0.3 0.2 11.5 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.25 KPA36551.1 - 1.3e-06 28.6 0.0 1.8e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA36551.1 - 7e-06 26.4 0.0 8.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA36551.1 - 0.0001 22.2 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KPA36551.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KPA36551.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KPA36551.1 - 0.0064 16.6 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Glyco_hydro_28 PF00295.17 KPA36552.1 - 1.5e-98 329.8 21.8 1.8e-98 329.6 21.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2180 PF09947.9 KPA36552.1 - 0.082 12.9 0.7 0.18 11.8 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) F-box PF00646.33 KPA36553.1 - 0.00012 21.9 0.0 0.00029 20.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KPA36553.1 - 0.0011 18.8 0.1 0.0011 18.8 0.1 1.5 2 0 0 2 2 2 1 F-box DUF2243 PF10002.9 KPA36554.1 - 0.073 13.2 0.0 0.77 9.9 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) DUF4131 PF13567.6 KPA36554.1 - 1.9 8.1 4.4 0.55 9.9 0.2 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) p450 PF00067.22 KPA36555.1 - 3.2e-70 237.1 0.0 4.6e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KPA36556.1 - 8.8e-20 71.2 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA36556.1 - 2.7e-16 60.1 0.0 1.6e-15 57.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA36556.1 - 8e-15 55.4 0.0 3.6e-14 53.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA36556.1 - 3.1e-14 53.4 0.0 9.6e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA36556.1 - 3.6e-10 39.8 0.0 8.5e-09 35.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA36556.1 - 2.2e-08 33.7 0.0 3.3e-07 29.9 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPA36556.1 - 0.00076 19.1 0.0 0.0038 16.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KPA36556.1 - 0.00093 18.7 0.0 0.0051 16.3 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KPA36556.1 - 0.004 16.6 0.0 0.011 15.2 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KPA36556.1 - 0.0078 16.0 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 KPA36556.1 - 0.019 14.2 0.0 0.054 12.8 0.0 1.8 1 1 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 KPA36556.1 - 0.071 13.2 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase FAD_binding_4 PF01565.23 KPA36557.1 - 6.1e-20 71.4 0.2 1e-19 70.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPA36557.1 - 9.3e-15 54.5 0.0 1.9e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KPA36557.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding ABC_membrane PF00664.23 KPA36559.1 - 2.9e-93 312.5 43.8 7.2e-51 173.4 16.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA36559.1 - 7.1e-65 217.7 0.0 3.8e-31 108.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPA36559.1 - 3.8e-12 46.1 11.4 0.0004 19.9 3.4 4.6 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KPA36559.1 - 3e-09 36.2 0.7 0.0018 17.1 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KPA36559.1 - 4.2e-08 32.8 0.6 0.0069 16.1 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KPA36559.1 - 1.7e-07 31.6 2.3 0.032 14.5 0.2 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KPA36559.1 - 1.8e-07 31.7 1.0 0.013 15.9 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KPA36559.1 - 2.6e-07 30.7 0.0 0.03 14.2 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KPA36559.1 - 7.5e-06 25.7 1.2 0.46 10.0 0.0 3.9 3 1 0 3 3 2 2 AAA domain AAA_15 PF13175.6 KPA36559.1 - 0.00011 22.0 0.0 0.35 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 KPA36559.1 - 0.00025 21.2 2.7 0.48 10.7 0.4 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KPA36559.1 - 0.00034 20.4 3.1 0.38 10.4 0.0 3.9 2 2 0 2 2 2 1 AAA domain AAA PF00004.29 KPA36559.1 - 0.0014 19.0 1.4 13 6.3 0.0 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KPA36559.1 - 0.0019 18.0 0.1 13 5.5 0.0 4.1 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KPA36559.1 - 0.0026 17.7 0.0 0.045 13.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 KPA36559.1 - 0.0034 17.5 0.0 4.2 7.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KPA36559.1 - 0.0042 17.3 0.3 5.4 7.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 KPA36559.1 - 0.0064 17.0 1.5 3.1 8.3 0.4 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KPA36559.1 - 0.0078 16.2 0.5 1.5 8.8 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KPA36559.1 - 0.0094 15.5 0.1 5.6 6.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KPA36559.1 - 0.017 15.5 0.9 3.7 8.0 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 KPA36559.1 - 0.022 15.3 0.0 15 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KPA36559.1 - 0.03 13.5 1.1 0.28 10.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 KPA36559.1 - 0.042 13.9 0.2 9.8 6.3 0.0 3.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 KPA36559.1 - 0.052 13.6 0.6 3.5 7.7 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain G-alpha PF00503.20 KPA36559.1 - 0.064 12.4 0.0 12 5.0 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit MoaE PF02391.17 KPA36559.1 - 0.077 13.3 0.3 10 6.5 0.1 2.5 2 0 0 2 2 2 0 MoaE protein PRK PF00485.18 KPA36559.1 - 0.091 12.5 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 KPA36559.1 - 0.14 11.9 1.3 17 5.1 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 KPA36559.1 - 0.14 11.4 0.4 5.5 6.2 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_24 PF13479.6 KPA36559.1 - 0.69 9.6 3.5 5.7 6.6 0.0 3.3 4 0 0 4 4 4 0 AAA domain Patatin PF01734.22 KPA36561.1 - 5.4e-13 49.6 0.2 1.7e-12 47.9 0.2 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Chromo PF00385.24 KPA36561.1 - 7.2e-07 29.0 1.6 1.3e-06 28.2 1.6 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tristanin_u2 PF16638.5 KPA36561.1 - 0.013 16.3 1.5 0.021 15.6 0.4 1.8 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers DUF3435 PF11917.8 KPA36562.1 - 4.2e-48 164.3 0.2 5.1e-48 164.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) FOXP-CC PF16159.5 KPA36562.1 - 0.026 15.2 0.2 0.093 13.4 0.2 1.9 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KPA36562.1 - 0.43 11.6 0.2 0.43 11.6 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPA36562.1 - 0.43 11.1 4.9 1.3 9.6 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain BNR_2 PF13088.6 KPA36563.1 - 0.00019 20.8 1.3 0.018 14.4 0.4 2.2 1 1 2 3 3 3 3 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KPA36563.1 - 0.0002 20.3 2.0 0.022 13.6 0.2 2.6 2 1 1 3 3 3 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 KPA36563.1 - 0.00023 20.7 5.8 0.092 12.8 0.8 3.3 2 0 0 2 2 2 2 BNR/Asp-box repeat RGS PF00615.19 KPA36564.1 - 3.6e-25 88.5 0.1 9.7e-25 87.1 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KPA36564.1 - 1.7e-18 66.4 0.0 1.5e-13 50.6 0.0 3.4 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Rrf2 PF02082.20 KPA36566.1 - 0.0032 17.8 0.0 0.015 15.7 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator Methyltransf_2 PF00891.18 KPA36566.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain Dimer_Tnp_Tn5 PF02281.16 KPA36566.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain Alfin PF12165.8 KPA36566.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Alfin Exo_endo_phos PF03372.23 KPA36569.1 - 1.5e-06 27.9 0.0 4.3e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Herpes_UL79 PF03049.14 KPA36570.1 - 0.19 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 UL79 family GATase_2 PF00310.21 KPA36571.1 - 0.087 11.5 0.0 0.1 11.3 0.0 1.0 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Sugar_tr PF00083.24 KPA36572.1 - 6.7e-89 298.8 24.6 9.9e-89 298.2 24.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36572.1 - 2e-17 63.2 38.3 2.3e-11 43.2 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 KPA36575.1 - 6.4e-21 74.7 1.0 5e-13 49.4 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA36575.1 - 1.2e-16 60.8 6.7 1.1e-06 29.0 0.1 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA36575.1 - 9e-15 53.3 1.8 0.00032 20.9 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KPA36575.1 - 1.2e-13 50.9 4.6 1.4e-05 25.2 0.1 4.0 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KPA36575.1 - 5.7e-13 48.7 8.6 3.2e-05 24.2 0.4 4.0 4 0 0 4 4 4 3 Ankyrin repeat DUF3140 PF11338.8 KPA36576.1 - 3.6e-36 123.5 2.7 3.6e-36 123.5 2.7 3.6 2 1 0 3 3 3 1 Protein of unknown function (DUF3140) Hva1_TUDOR PF11160.8 KPA36576.1 - 3.1e-14 52.9 2.6 1.7e-13 50.5 2.6 2.4 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain zf-CCCH PF00642.24 KPA36577.1 - 2.4e-08 33.7 1.4 2.4e-08 33.7 1.4 3.4 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KPA36577.1 - 4.9e-07 29.6 5.0 4.9e-07 29.6 5.0 3.6 4 1 0 4 4 4 1 Zinc finger domain zf-CCCH_4 PF18044.1 KPA36577.1 - 2e-06 27.4 1.9 2e-06 27.4 1.9 3.7 6 0 0 6 6 6 1 CCCH-type zinc finger Torus PF16131.5 KPA36577.1 - 4.5e-05 24.1 0.1 4.5e-05 24.1 0.1 2.5 3 0 0 3 3 3 1 Torus domain zf-CCCH_3 PF15663.5 KPA36577.1 - 0.56 10.4 9.4 0.5 10.6 0.2 3.0 2 1 1 3 3 3 0 Zinc-finger containing family Oxidored_FMN PF00724.20 KPA36578.1 - 3e-73 247.1 0.0 3.1e-53 181.2 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Bul1_N PF04425.12 KPA36579.1 - 1.4e-06 27.3 0.2 0.004 16.0 0.0 3.2 2 1 1 3 3 3 3 Bul1 N terminus Bul1_C PF04426.12 KPA36579.1 - 4e-06 26.4 0.0 6.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.29 KPA36579.1 - 2e-05 24.7 0.0 4.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain p450 PF00067.22 KPA36580.1 - 1.8e-77 261.1 0.0 2.3e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.14 KPA36581.1 - 6e-13 48.7 0.1 1.8e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA36581.1 - 0.0041 16.7 0.5 0.015 14.9 0.3 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPA36581.1 - 0.0085 16.1 0.1 0.039 13.9 0.1 2.0 1 1 1 2 2 2 1 FAD-NAD(P)-binding Malic_M PF03949.15 KPA36581.1 - 0.022 14.0 0.1 0.6 9.3 0.1 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Sacchrp_dh_NADP PF03435.18 KPA36581.1 - 0.04 14.2 0.0 0.097 12.9 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Lycopene_cycl PF05834.12 KPA36581.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KPA36581.1 - 0.079 12.2 0.6 5.4 6.2 0.2 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KPA36581.1 - 0.11 13.1 0.1 0.23 12.0 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HTH_Tnp_Tc5 PF03221.16 KPA36582.1 - 0.0073 16.3 0.1 0.021 14.8 0.1 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain dCMP_cyt_deam_1 PF00383.23 KPA36583.1 - 2.3e-07 30.6 0.0 3.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KPA36583.1 - 3.7e-07 30.0 0.0 6.6e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 MafB19-like deaminase RecR PF02132.15 KPA36583.1 - 0.008 15.7 1.0 0.021 14.4 1.0 1.7 1 0 0 1 1 1 1 RecR protein Cep57_MT_bd PF06657.13 KPA36583.1 - 0.17 12.4 1.9 5.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 NPCBM_assoc PF10633.9 KPA36584.1 - 0.018 15.3 0.1 4.2 7.7 0.0 2.5 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Dimer_Tnp_hAT PF05699.14 KPA36587.1 - 3.1e-14 52.5 0.1 7e-14 51.4 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2465 PF10239.9 KPA36587.1 - 0.00022 20.6 1.2 0.062 12.5 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2465) Ferric_reduct PF01794.19 KPA36588.1 - 4.8e-24 84.9 10.7 4.8e-24 84.9 10.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPA36588.1 - 2.5e-14 53.7 0.0 7.3e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPA36588.1 - 7.4e-11 42.1 0.1 3.2e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KPA36588.1 - 4e-05 24.2 0.0 0.0001 22.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Sdh_cyt PF01127.22 KPA36588.1 - 6.9 6.7 14.6 0.2 11.7 4.4 3.0 4 0 0 4 4 4 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ctr PF04145.15 KPA36589.1 - 7.2e-33 114.3 5.0 8.9e-33 114.0 5.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.19 KPA36590.1 - 5e-15 55.7 17.2 5e-15 55.7 17.2 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KPA36590.1 - 2.8e-07 30.6 0.0 1.5e-05 25.0 0.0 2.7 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 KPA36590.1 - 0.021 14.9 0.5 6.2 6.9 0.4 2.3 1 1 1 2 2 2 0 Ferric reductase NAD binding domain MLANA PF14991.6 KPA36590.1 - 1.2 9.4 5.0 0.95 9.8 1.9 2.2 2 0 0 2 2 2 0 Protein melan-A ADH_zinc_N PF00107.26 KPA36591.1 - 2e-18 66.6 0.0 2.9e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPA36591.1 - 4.6e-17 61.9 0.0 8.2e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KPA36591.1 - 1.4e-05 26.2 0.0 2.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PLA2_B PF01735.18 KPA36592.1 - 3.6e-154 513.8 3.6 4.6e-154 513.5 3.6 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Uds1 PF15456.6 KPA36593.1 - 0.0073 16.5 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 Up-regulated During Septation Rnk_N PF14760.6 KPA36593.1 - 1.3 9.6 4.8 0.5 10.9 0.7 2.4 2 0 0 2 2 2 0 Rnk N-terminus SET PF00856.28 KPA36594.1 - 2.8e-12 47.3 0.2 1.3e-11 45.2 0.2 1.9 1 1 0 1 1 1 1 SET domain Herp-Cyclin PF09241.10 KPA36594.1 - 0.013 16.2 1.0 0.042 14.5 0.2 1.9 2 0 0 2 2 2 0 Herpesviridae viral cyclin CENP_C_N PF15622.6 KPA36595.1 - 0.0023 17.4 0.7 0.0028 17.2 0.7 1.1 1 0 0 1 1 1 1 Kinetochore assembly subunit CENP-C N-terminal FAD_binding_3 PF01494.19 KPA36596.1 - 1.9e-20 73.5 0.9 3.9e-19 69.1 0.9 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA36596.1 - 4.2e-11 42.6 0.4 8.1e-07 28.6 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA36596.1 - 7.9e-09 35.6 0.4 5.3e-05 23.0 0.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA36596.1 - 5.6e-08 33.2 0.3 1.4e-06 28.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA36596.1 - 1.6e-05 25.1 0.0 3.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KPA36596.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KPA36596.1 - 0.0024 16.8 0.2 0.039 12.8 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase ApbA PF02558.16 KPA36596.1 - 0.0033 17.1 0.1 0.016 14.8 0.0 1.9 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA CoA_transf_3 PF02515.17 KPA36596.1 - 0.0066 15.6 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III Lycopene_cycl PF05834.12 KPA36596.1 - 0.01 14.9 0.0 0.025 13.6 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPA36596.1 - 0.024 13.8 0.2 0.04 13.0 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KPA36596.1 - 0.042 12.9 0.1 0.058 12.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KPA36596.1 - 0.044 13.7 0.1 0.074 12.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KPA36596.1 - 0.064 13.7 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 KPA36596.1 - 0.067 12.5 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA36596.1 - 0.074 12.3 0.0 0.24 10.6 0.0 1.7 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Dimer_Tnp_hAT PF05699.14 KPA36597.1 - 2.8e-12 46.3 0.1 6e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Glyco_hydro_11 PF00457.17 KPA36599.1 - 3.3e-76 254.9 22.5 3.9e-76 254.6 22.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Guanylate_kin PF00625.21 KPA36601.1 - 3e-48 163.9 0.0 3.7e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 KPA36601.1 - 0.0027 17.8 0.0 0.006 16.6 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA36601.1 - 0.006 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 KPA36601.1 - 0.0067 17.0 0.1 0.014 15.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA36601.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KPA36601.1 - 0.019 15.2 0.0 0.043 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KPA36601.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KPA36601.1 - 0.035 14.4 0.0 0.069 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KPA36601.1 - 0.049 13.7 0.0 0.085 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 KPA36601.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase p450 PF00067.22 KPA36602.1 - 1.2e-39 136.4 0.0 1.5e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.29 KPA36603.1 - 1.8e-17 64.0 0.0 4e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA36603.1 - 0.0061 16.8 0.3 0.075 13.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KPA36603.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KPA36603.1 - 0.0075 16.7 1.1 0.038 14.4 0.2 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KPA36603.1 - 0.039 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KPA36603.1 - 0.057 12.7 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 KPA36603.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KPA36603.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KPA36603.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Chitin_synth_1 PF01644.17 KPA36604.1 - 2.6e-66 222.6 0.0 3.7e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KPA36604.1 - 1.2e-27 95.6 0.0 2.7e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KPA36604.1 - 1.3e-24 86.7 0.2 3.5e-20 72.1 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KPA36604.1 - 7.3e-09 35.8 0.4 2.2e-08 34.2 0.4 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Helicase_C PF00271.31 KPA36605.1 - 4e-18 65.8 0.0 1.5e-17 63.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPA36605.1 - 1.6e-06 28.0 0.0 1.3e-05 25.1 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KPA36605.1 - 7.6e-05 23.4 0.3 0.00021 21.9 0.3 1.8 1 0 0 1 1 1 1 RecQ zinc-binding SNF2_N PF00176.23 KPA36605.1 - 0.0087 14.8 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF5097 PF17020.5 KPA36605.1 - 0.1 13.0 0.1 0.65 10.4 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5097) DUF1003 PF06210.11 KPA36606.1 - 0.087 12.9 0.3 0.25 11.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) TssN PF17555.2 KPA36606.1 - 8.7 5.6 11.7 2.6 7.3 5.5 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssN COX4_pro_2 PF07835.12 KPA36608.1 - 0.17 12.0 0.2 0.62 10.2 0.1 2.0 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV ABC2_membrane PF01061.24 KPA36609.1 - 2.8e-71 239.3 59.0 2.6e-40 138.1 18.9 3.0 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KPA36609.1 - 7.6e-33 112.3 12.9 2.2e-30 104.4 0.0 3.7 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.27 KPA36609.1 - 5.3e-32 111.2 0.0 2.2e-15 57.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KPA36609.1 - 1.1e-16 61.2 0.0 3e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KPA36609.1 - 7.4e-06 25.7 0.0 3.3e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KPA36609.1 - 1e-05 25.5 0.2 0.00018 21.4 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KPA36609.1 - 2.1e-05 24.9 0.0 0.015 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 KPA36609.1 - 7.1e-05 22.1 15.4 7.1e-05 22.1 15.4 2.6 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_33 PF13671.6 KPA36609.1 - 9.1e-05 22.6 0.2 0.08 13.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KPA36609.1 - 0.00011 22.7 0.0 0.02 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KPA36609.1 - 0.00025 20.5 0.0 0.038 13.4 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPA36609.1 - 0.0012 18.5 0.8 0.015 15.0 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 KPA36609.1 - 0.0012 19.2 0.0 0.47 10.9 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KPA36609.1 - 0.0043 16.9 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KPA36609.1 - 0.013 15.1 1.1 0.42 10.2 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KPA36609.1 - 0.013 15.7 1.2 2.5 8.4 0.2 3.0 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 KPA36609.1 - 0.014 15.2 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KPA36609.1 - 0.025 14.5 2.2 2 8.3 0.1 2.8 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 KPA36609.1 - 0.036 13.8 0.1 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KPA36609.1 - 0.041 14.1 3.4 0.5 10.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KPA36609.1 - 0.08 13.4 0.2 17 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KPA36609.1 - 0.1 12.6 0.2 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KPA36609.1 - 0.16 12.3 0.3 14 6.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain Zn_clus PF00172.18 KPA36610.1 - 6.1e-05 23.1 3.8 0.00014 21.9 3.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 KPA36611.1 - 7.7e-07 29.3 1.9 7.4e-05 22.9 1.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily APH PF01636.23 KPA36612.1 - 2.3e-15 57.2 0.0 5.2e-15 56.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KPA36612.1 - 1.3e-05 24.2 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KPA36612.1 - 0.00015 21.2 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KPA36612.1 - 0.034 13.7 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase MCR PF18509.1 KPA36614.1 - 0.019 14.6 0.2 0.032 13.8 0.2 1.4 1 0 0 1 1 1 0 Magnetochrome domain APC_basic PF05956.11 KPA36614.1 - 0.1 12.0 0.8 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 APC basic domain FMN_bind_2 PF04299.12 KPA36617.1 - 4e-61 205.6 0.2 4.7e-61 205.4 0.2 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Sugar_tr PF00083.24 KPA36618.1 - 6.9e-136 453.7 28.0 7.9e-136 453.5 28.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36618.1 - 6.5e-25 87.8 32.3 1.1e-15 57.5 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SirB PF04247.12 KPA36618.1 - 0.57 10.3 9.2 0.93 9.6 1.4 3.1 2 2 0 2 2 2 0 Invasion gene expression up-regulator, SirB 7tm_1 PF00001.21 KPA36618.1 - 1.6 8.0 6.9 0.2 10.9 0.2 2.3 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF469 PF04320.14 KPA36619.1 - 0.12 13.3 0.1 0.17 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein with unknown function (DUF469) Chromo PF00385.24 KPA36621.1 - 2.5e-08 33.7 0.1 8.1e-08 32.1 0.2 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PARM PF17061.5 KPA36621.1 - 0.086 13.0 14.6 0.18 11.9 14.6 1.7 1 0 0 1 1 1 0 PARM ELM2 PF01448.24 KPA36621.1 - 1.7 9.5 4.4 13 6.6 1.9 3.1 2 1 0 2 2 2 0 ELM2 domain DUF2828 PF11443.8 KPA36623.1 - 1.7e-245 816.0 0.0 2e-245 815.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) REV1_C PF16727.5 KPA36623.1 - 0.1 13.0 0.0 0.87 10.0 0.0 2.3 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain IQCJ-SCHIP1 PF15157.6 KPA36623.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DsbC_N PF10411.9 KPA36624.1 - 0.023 14.1 0.2 0.06 12.8 0.0 1.7 2 0 0 2 2 2 0 Disulfide bond isomerase protein N-terminus DUF1996 PF09362.10 KPA36625.1 - 6.4e-46 157.2 0.3 8e-46 156.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pro_racemase PF05544.11 KPA36626.1 - 9.2e-118 393.0 0.1 1e-117 392.8 0.1 1.0 1 0 0 1 1 1 1 Proline racemase DAO PF01266.24 KPA36627.1 - 1.1e-38 133.8 0.7 1.2e-38 133.6 0.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA36627.1 - 1.9e-05 25.1 0.7 0.00036 21.0 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPA36627.1 - 0.0001 21.6 0.0 0.00019 20.6 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KPA36627.1 - 0.00045 19.6 1.0 0.00069 19.0 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KPA36627.1 - 0.00053 20.2 0.1 0.0022 18.2 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KPA36627.1 - 0.0011 19.3 0.0 0.0026 18.2 0.0 1.7 2 0 0 2 2 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KPA36627.1 - 0.0037 16.6 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KPA36627.1 - 0.0071 15.9 0.9 0.014 15.0 0.9 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KPA36627.1 - 0.0082 15.8 0.4 0.018 14.7 0.4 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KPA36627.1 - 0.0095 15.8 0.5 0.018 14.9 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KPA36627.1 - 0.01 15.1 0.8 0.022 14.0 0.3 1.8 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 KPA36627.1 - 0.083 12.0 0.3 0.14 11.3 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPA36627.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA36627.1 - 0.2 10.6 0.1 6 5.8 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KPA36627.1 - 0.22 10.2 0.6 0.33 9.6 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KPA36627.1 - 0.41 9.9 2.0 3.9 6.7 2.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Sugar_tr PF00083.24 KPA36628.1 - 1.5e-102 343.8 19.4 1.8e-102 343.6 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36628.1 - 3.3e-27 95.4 40.2 3.2e-25 88.8 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA36628.1 - 2.6e-05 22.9 0.3 4.4e-05 22.1 0.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 KPA36628.1 - 0.0014 17.6 3.6 0.0018 17.3 0.4 2.2 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM DUF2530 PF10745.9 KPA36628.1 - 1 9.7 3.7 1.4 9.2 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Ysc84 PF04366.12 KPA36629.1 - 4.4e-48 162.3 0.1 6.8e-48 161.6 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Acetyltransf_1 PF00583.25 KPA36630.1 - 2.6e-16 59.9 0.0 3.3e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA36630.1 - 7e-10 39.2 0.0 1e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA36630.1 - 5.3e-08 32.8 0.0 8e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA36630.1 - 2.5e-06 27.6 0.0 3.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA36630.1 - 1.5e-05 25.1 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KPA36630.1 - 5.7e-05 23.3 0.0 0.00011 22.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KPA36630.1 - 0.0008 18.9 0.0 0.00086 18.8 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 KPA36630.1 - 0.001 19.7 0.0 0.0012 19.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KPA36630.1 - 0.0014 18.6 0.1 0.0039 17.1 0.0 1.8 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase FR47 PF08445.10 KPA36630.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Zip PF02535.22 KPA36631.1 - 2 7.6 6.8 0.061 12.5 0.6 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter 3Beta_HSD PF01073.19 KPA36632.1 - 6.1e-15 55.0 0.0 4.7e-12 45.5 0.0 2.6 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPA36632.1 - 1.3e-10 41.2 0.0 2.7e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPA36632.1 - 3.8e-07 29.5 0.0 5.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KPA36632.1 - 5.9e-07 28.9 0.0 7.1e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KPA36632.1 - 1.3e-05 24.7 0.1 0.0002 20.9 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KPA36632.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPA36632.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Glyco_hydro_88 PF07470.13 KPA36633.1 - 2.9e-67 227.2 3.1 3.7e-67 226.9 3.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 KPA36633.1 - 0.026 13.8 2.7 0.041 13.1 0.4 2.4 3 0 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Sugar_tr PF00083.24 KPA36634.1 - 2.8e-76 257.2 8.9 3.3e-76 257.0 8.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36634.1 - 1.9e-25 89.6 16.8 1.9e-25 89.6 16.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA36634.1 - 5.1e-07 28.5 0.2 8.6e-07 27.8 0.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KPA36634.1 - 2.3e-06 26.4 2.8 0.00049 18.8 0.0 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein GST_N_3 PF13417.6 KPA36635.1 - 3.6e-11 43.3 0.0 7.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPA36635.1 - 5.4e-08 33.0 0.0 1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPA36635.1 - 0.0013 18.9 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPA36635.1 - 0.002 18.1 0.0 0.005 16.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KPA36635.1 - 0.036 14.4 0.0 0.083 13.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KPA36635.1 - 0.15 12.9 0.0 0.36 11.6 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF2434 PF10361.9 KPA36636.1 - 1.3e-131 438.0 9.7 1.6e-131 437.6 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) COG5 PF10392.9 KPA36637.1 - 5.4e-37 126.9 0.1 5.4e-37 126.9 0.1 2.2 3 0 0 3 3 3 1 Golgi transport complex subunit 5 DUF348 PF03990.14 KPA36637.1 - 0.032 14.0 0.1 0.11 12.2 0.1 2.0 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain Gelsolin PF00626.22 KPA36638.1 - 1.1e-34 118.1 0.1 1.5e-11 44.0 0.1 3.2 3 0 0 3 3 3 3 Gelsolin repeat Glyco_hydro_3_C PF01915.22 KPA36639.1 - 2.5e-57 194.2 0.0 3.8e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPA36639.1 - 1.1e-51 176.2 0.0 1.9e-51 175.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPA36639.1 - 5.7e-19 68.0 0.1 1.6e-18 66.5 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KPA36639.1 - 4.9e-13 49.1 0.0 8.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Zn_clus PF00172.18 KPA36640.1 - 4.5e-09 36.3 11.5 7.8e-09 35.5 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA36640.1 - 0.027 13.5 0.2 0.051 12.6 0.2 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Sugar_tr PF00083.24 KPA36641.1 - 8.2e-84 282.0 23.1 1.2e-83 281.5 23.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter CN_hydrolase PF00795.22 KPA36641.1 - 3.4e-33 115.1 0.0 2.4e-32 112.3 0.0 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 KPA36641.1 - 5.9e-24 84.6 28.5 5.9e-24 84.6 28.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 KPA36641.1 - 0.0045 16.0 11.0 0.0045 16.0 11.0 1.9 2 0 0 2 2 2 1 PUCC protein OATP PF03137.20 KPA36641.1 - 0.11 10.7 7.0 0.043 12.1 3.4 2.2 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 KPA36642.1 - 0.017 14.1 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF5597 PF18120.1 KPA36643.1 - 5.1e-27 94.6 0.1 9e-27 93.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 KPA36643.1 - 2.6e-12 46.8 0.0 4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 KPA36643.1 - 6.7e-08 32.5 0.0 5.8e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.20 KPA36643.1 - 0.086 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 HMGL-like PF00682.19 KPA36644.1 - 1e-71 241.6 0.1 1.6e-71 241.0 0.1 1.3 1 0 0 1 1 1 1 HMGL-like AP_endonuc_2 PF01261.24 KPA36644.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel POT1 PF02765.17 KPA36644.1 - 0.049 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 adh_short PF00106.25 KPA36645.1 - 3.2e-32 111.6 0.0 4.2e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA36645.1 - 1.2e-24 87.2 0.0 1.6e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA36645.1 - 0.00015 21.8 0.3 0.0026 17.7 0.2 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KPA36645.1 - 0.00039 20.0 0.1 0.00073 19.1 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RRM_occluded PF16842.5 KPA36645.1 - 0.13 12.2 0.1 3.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif p450 PF00067.22 KPA36646.1 - 6.7e-55 186.7 0.0 8e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 3HCDH_N PF02737.18 KPA36647.1 - 5e-31 108.0 0.0 8e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KPA36647.1 - 2.1e-16 60.3 0.0 4.2e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SGL PF08450.12 KPA36647.1 - 0.00016 21.3 0.1 0.0016 18.1 0.0 2.4 2 2 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region XdhC_C PF13478.6 KPA36647.1 - 0.0017 18.9 0.1 0.0081 16.7 0.0 2.1 3 0 0 3 3 3 1 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.23 KPA36647.1 - 0.0097 15.9 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KPA36647.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ldl_recept_b PF00058.17 KPA36647.1 - 0.039 14.4 3.4 26 5.4 0.0 4.5 4 1 0 4 4 4 0 Low-density lipoprotein receptor repeat class B NAD_binding_7 PF13241.6 KPA36647.1 - 0.047 14.1 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Arylesterase PF01731.20 KPA36647.1 - 0.048 13.9 0.0 1.1 9.5 0.0 3.2 5 0 0 5 5 5 0 Arylesterase 2-Hacid_dh_C PF02826.19 KPA36647.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KPA36647.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HET PF06985.11 KPA36648.1 - 1.3e-29 103.4 0.1 1.3e-29 103.4 0.1 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF2891 PF11199.8 KPA36648.1 - 0.022 13.7 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) Methyltransf_25 PF13649.6 KPA36649.1 - 9.6e-06 26.2 0.1 2.4e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA36649.1 - 1.5e-05 24.8 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA36649.1 - 0.0017 19.0 0.1 0.0066 17.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA36649.1 - 0.0029 17.4 0.0 0.0068 16.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KPA36649.1 - 0.0047 16.4 0.0 0.0067 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Dimerisation2 PF16864.5 KPA36649.1 - 0.0067 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_2 PF00891.18 KPA36649.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KPA36649.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KPA36649.1 - 0.018 15.7 0.0 0.052 14.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.12 KPA36649.1 - 0.091 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 KPA36649.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CoA_transf_3 PF02515.17 KPA36650.1 - 7.9e-19 68.0 0.0 9.3e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III p450 PF00067.22 KPA36651.1 - 2.5e-70 237.5 0.0 2.7e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KPA36652.1 - 3.9e-15 55.6 0.1 6.8e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA36652.1 - 7.9e-05 22.7 5.8 0.00016 21.8 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.11 KPA36652.1 - 0.015 15.4 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Med9 PF07544.13 KPA36652.1 - 0.16 12.1 0.8 2.1 8.5 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Dabb PF07876.12 KPA36653.1 - 4.8e-13 49.5 0.1 5.4e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4971 PF16341.5 KPA36653.1 - 0.029 14.2 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) Casc1 PF12366.8 KPA36653.1 - 0.067 12.7 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF3223 PF11523.8 KPA36653.1 - 0.078 13.8 0.1 0.11 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3223) FAA_hydrolase PF01557.18 KPA36654.1 - 2.4e-44 151.6 0.0 7.7e-44 150.0 0.0 1.7 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KPA36654.1 - 2.5e-33 114.5 0.0 7.1e-33 113.0 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal HgmA PF04209.13 KPA36655.1 - 1e-194 647.1 0.0 1.2e-194 646.9 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AA_permease_2 PF13520.6 KPA36656.1 - 6.5e-33 114.2 24.8 6.5e-33 114.2 24.8 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KPA36656.1 - 8.2e-11 41.2 27.5 1.1e-10 40.7 27.5 1.1 1 0 0 1 1 1 1 Amino acid permease MFS18 PF17352.2 KPA36656.1 - 0.16 12.3 1.7 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 Male Flower Specific protein 18 Trp_oprn_chp PF09534.10 KPA36657.1 - 0.0043 16.9 0.2 0.0069 16.2 0.2 1.2 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Phage_HK97_TLTM PF06120.11 KPA36657.1 - 0.032 13.4 0.2 0.047 12.9 0.2 1.2 1 0 0 1 1 1 0 Tail length tape measure protein DUF5305 PF17231.2 KPA36657.1 - 0.054 12.9 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Nitrate_red_gam PF02665.14 KPA36657.1 - 0.067 12.7 0.1 0.093 12.3 0.1 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit CbtA PF09490.10 KPA36657.1 - 0.069 12.9 0.0 0.097 12.4 0.0 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) PPDFL PF15060.6 KPA36657.1 - 0.074 13.6 0.1 2.4 8.7 0.1 2.5 2 0 0 2 2 2 0 Differentiation and proliferation regulator Amnionless PF14828.6 KPA36657.1 - 0.086 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless DNA_repr_REX1B PF14966.6 KPA36658.1 - 0.28 11.9 0.8 0.41 11.3 0.2 1.5 2 0 0 2 2 2 0 DNA repair REX1-B Mucin PF01456.17 KPA36658.1 - 2.2 8.2 25.8 3.1 7.8 25.8 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Nramp PF01566.18 KPA36659.1 - 1.3e-75 254.7 15.0 1.3e-75 254.7 15.0 2.6 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein bZIP_1 PF00170.21 KPA36660.1 - 0.82 9.8 5.8 1.5 8.9 5.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor NmrA PF05368.13 KPA36661.1 - 2.6e-22 79.5 0.0 3.1e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA36661.1 - 1.2e-15 57.9 0.0 1.7e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding AFOR_C PF01314.18 KPA36661.1 - 0.0085 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 3Beta_HSD PF01073.19 KPA36661.1 - 0.055 12.5 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.16 KPA36663.1 - 1.2e-22 80.4 67.0 9.7e-17 60.9 32.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cas1_AcylT PF07779.12 KPA36664.1 - 1.6e-98 330.7 11.5 2.3e-98 330.2 11.5 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF4318 PF14201.6 KPA36665.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) COesterase PF00135.28 KPA36666.1 - 7.1e-85 285.8 0.0 9.2e-85 285.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA36666.1 - 1.7e-06 28.1 0.3 6.2e-06 26.2 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA36666.1 - 0.091 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family TSP_3 PF02412.18 KPA36666.1 - 7.7 6.3 6.6 3.4 7.4 2.4 2.2 2 0 0 2 2 2 0 Thrombospondin type 3 repeat CFEM PF05730.11 KPA36667.1 - 2.9e-08 33.7 14.4 4.1e-08 33.2 14.4 1.2 1 0 0 1 1 1 1 CFEM domain DUF3638 PF12340.8 KPA36668.1 - 5.8e-102 339.8 0.7 9.7e-102 339.1 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KPA36668.1 - 1.4e-18 66.0 0.4 2.8e-18 65.0 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) OrsD PF12013.8 KPA36669.1 - 1.2e-06 29.0 0.5 2.6e-06 27.9 0.5 1.6 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-BED PF02892.15 KPA36669.1 - 0.16 12.0 1.1 0.51 10.4 1.1 1.8 1 0 0 1 1 1 0 BED zinc finger PAT1 PF09770.9 KPA36670.1 - 0.01 14.1 0.9 1.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Tannase PF07519.11 KPA36671.1 - 1.5e-48 165.9 0.0 1.7e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Glyco_hydro_7 PF00840.20 KPA36671.1 - 0.0049 15.6 0.1 0.0077 15.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 AA_permease_2 PF13520.6 KPA36672.1 - 2e-57 194.9 49.6 2e-57 194.9 49.6 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA36672.1 - 1.6e-26 92.9 37.1 2.1e-26 92.5 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2070 PF09843.9 KPA36672.1 - 2.6 6.2 17.4 0.9 7.7 5.7 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) RTA1 PF04479.13 KPA36675.1 - 8.9e-35 120.2 4.5 8.9e-35 120.2 4.5 1.5 2 0 0 2 2 2 1 RTA1 like protein Amino_oxidase PF01593.24 KPA36677.1 - 6.3e-65 220.2 0.1 7e-63 213.5 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA36677.1 - 4.2e-09 36.5 0.0 9.6e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA36677.1 - 7.3e-09 35.3 0.3 0.00053 19.3 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA36677.1 - 3.8e-05 23.1 1.3 0.0011 18.3 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KPA36677.1 - 0.00033 20.1 0.0 0.00055 19.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.27 KPA36677.1 - 0.00044 20.8 1.7 0.07 13.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KPA36677.1 - 0.00095 19.2 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KPA36677.1 - 0.0016 17.3 0.9 0.028 13.1 0.4 2.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KPA36677.1 - 0.0022 17.3 0.1 0.0048 16.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KPA36677.1 - 0.0027 16.9 0.2 0.0065 15.6 0.2 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KPA36677.1 - 0.012 15.2 0.9 0.35 10.4 0.2 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase IlvN PF07991.12 KPA36677.1 - 0.025 14.2 0.0 0.079 12.5 0.1 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_oxidored PF12831.7 KPA36677.1 - 0.04 13.3 2.8 0.044 13.1 1.0 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KPA36677.1 - 0.064 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KPA36677.1 - 0.088 12.8 0.1 10 6.1 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding F420_oxidored PF03807.17 KPA36677.1 - 0.18 12.4 0.2 0.63 10.7 0.3 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 KPA36677.1 - 0.33 10.0 2.9 0.14 11.2 0.4 1.5 2 0 0 2 2 2 0 FAD binding domain Metallophos PF00149.28 KPA36678.1 - 2.5e-17 64.0 0.1 3.9e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GST_N_2 PF13409.6 KPA36680.1 - 6.8e-20 71.1 0.0 1.3e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPA36680.1 - 3.7e-06 27.2 0.0 0.00034 21.0 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPA36680.1 - 2.1e-05 24.4 0.0 4.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA36680.1 - 0.001 19.2 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KPA36680.1 - 0.015 15.0 0.0 0.079 12.8 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA36680.1 - 0.031 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain vATP-synt_AC39 PF01992.16 KPA36680.1 - 0.21 11.1 0.0 0.31 10.5 0.0 1.1 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit Repressor_Mnt PF11423.8 KPA36680.1 - 0.46 10.3 2.3 1.2 9.0 0.5 2.5 2 0 0 2 2 2 0 Regulatory protein Mnt peroxidase PF00141.23 KPA36681.1 - 1e-22 81.0 0.6 2.3e-22 79.8 0.3 1.6 2 0 0 2 2 2 1 Peroxidase Abhydrolase_6 PF12697.7 KPA36683.1 - 3.1e-05 24.7 0.0 5.3e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KPA36683.1 - 3.7e-05 23.6 0.0 6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 KPA36683.1 - 0.0027 17.6 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 KPA36683.1 - 0.011 15.5 0.0 0.027 14.1 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA36683.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KPA36683.1 - 0.023 14.2 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 KPA36683.1 - 0.13 12.1 0.1 1.3 8.9 0.0 2.3 3 0 0 3 3 3 0 Serine hydrolase HTH_Tnp_Tc5 PF03221.16 KPA36684.1 - 1.6e-10 40.9 0.0 7.2e-10 38.8 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KPA36684.1 - 5.8e-08 32.6 0.0 2.1e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease RTA1 PF04479.13 KPA36685.1 - 1.5e-44 152.1 8.9 2.1e-36 125.5 0.9 2.8 2 1 1 3 3 3 2 RTA1 like protein DUF1270 PF06900.11 KPA36685.1 - 4.2 7.8 6.1 1.1 9.7 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) Zn_clus PF00172.18 KPA36686.1 - 2.9e-08 33.7 5.8 4.6e-08 33.0 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA36686.1 - 0.0014 17.5 0.2 0.0018 17.2 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 KPA36687.1 - 1.5e-06 28.4 0.0 1.8e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA36687.1 - 3.9e-06 27.2 0.0 5.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA36687.1 - 2.5e-05 24.2 0.0 3.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA36687.1 - 0.022 14.9 0.0 0.04 14.1 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4821 PF16092.5 KPA36687.1 - 0.023 14.3 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) Ank_2 PF12796.7 KPA36688.1 - 4.7e-63 209.8 0.5 2.4e-12 47.2 0.0 7.8 3 3 6 9 9 9 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA36688.1 - 1.7e-42 142.9 0.6 8.1e-07 29.2 0.0 9.7 6 3 3 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPA36688.1 - 7.4e-42 141.2 0.2 0.0018 18.8 0.0 10.2 6 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA36688.1 - 1.9e-34 113.8 0.0 0.016 15.7 0.0 14.8 16 0 0 16 16 16 7 Ankyrin repeat Ank PF00023.30 KPA36688.1 - 8.5e-33 111.4 0.0 0.033 14.6 0.0 13.0 13 1 0 13 13 13 7 Ankyrin repeat Propep_M14 PF02244.16 KPA36688.1 - 0.41 11.1 2.3 0.53 10.7 0.1 2.4 3 0 0 3 3 3 0 Carboxypeptidase activation peptide CorA PF01544.18 KPA36688.1 - 1.3 8.3 3.9 2.3 7.5 0.3 2.7 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein BCS1_N PF08740.11 KPA36689.1 - 1.5e-35 122.9 0.2 2.8e-35 122.0 0.2 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KPA36689.1 - 5.5e-23 81.8 0.0 1.1e-22 80.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPA36689.1 - 8.4e-06 25.6 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KPA36689.1 - 0.0052 17.3 0.0 0.009 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KPA36689.1 - 0.012 16.0 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KPA36689.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 KPA36689.1 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPA36689.1 - 0.09 13.2 0.1 0.24 11.7 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain TIP49 PF06068.13 KPA36689.1 - 0.2 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KPA36689.1 - 0.21 11.3 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NmrA PF05368.13 KPA36690.1 - 1.4e-16 60.8 0.0 2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA36690.1 - 6.3e-16 58.8 0.1 1.5e-15 57.5 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA36690.1 - 8.9e-06 25.3 0.1 0.00035 20.1 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPA36690.1 - 0.00018 21.5 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 KPA36690.1 - 0.0017 18.5 0.1 0.005 17.0 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 KPA36690.1 - 0.0019 18.3 0.0 0.0057 16.7 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KPA36690.1 - 0.0035 17.6 0.2 0.017 15.4 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KPA36690.1 - 0.028 13.6 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 KPA36690.1 - 0.035 14.4 0.1 0.075 13.3 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 KPA36690.1 - 0.088 13.4 0.1 0.42 11.2 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PglD_N PF17836.1 KPA36690.1 - 0.15 12.7 0.0 0.4 11.4 0.0 1.7 1 0 0 1 1 1 0 PglD N-terminal domain 3Beta_HSD PF01073.19 KPA36690.1 - 0.21 10.5 0.0 0.36 9.8 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Zn_clus PF00172.18 KPA36691.1 - 3.3e-05 23.9 9.1 6.3e-05 23.0 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipoxygenase PF00305.19 KPA36692.1 - 1.6e-50 172.3 1.1 4e-50 171.0 1.1 1.4 1 1 0 1 1 1 1 Lipoxygenase SLATT_5 PF18160.1 KPA36694.1 - 0.17 11.2 0.1 0.17 11.2 0.1 2.7 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 Cerato-platanin PF07249.12 KPA36695.1 - 0.0012 18.9 0.2 0.0038 17.3 0.0 1.9 2 0 0 2 2 2 1 Cerato-platanin Glyco_hydro_75 PF07335.11 KPA36696.1 - 3.5e-64 216.0 0.2 5.3e-64 215.4 0.2 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Methyltransf_23 PF13489.6 KPA36697.1 - 1.9e-24 86.4 0.0 2.7e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA36697.1 - 5.6e-10 39.8 0.0 1.4e-09 38.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA36697.1 - 7.1e-07 29.9 0.0 5.7e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA36697.1 - 1.6e-06 28.6 0.0 4.5e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA36697.1 - 1.9e-05 24.5 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KPA36697.1 - 0.0028 17.0 0.0 0.059 12.7 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KPA36697.1 - 0.0043 16.8 0.2 0.19 11.4 0.2 2.2 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KPA36697.1 - 0.012 15.2 0.0 0.046 13.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 KPA36697.1 - 0.026 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Tannase PF07519.11 KPA36698.1 - 7.5e-52 176.8 0.7 9.4e-52 176.5 0.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KPA36698.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_transf_8 PF01501.20 KPA36700.1 - 7.8e-09 35.4 4.0 3.1e-08 33.5 4.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Aldo_ket_red PF00248.21 KPA36701.1 - 1.7e-47 162.0 0.0 4e-45 154.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.11 KPA36701.1 - 0.001 18.4 0.1 3.2 7.2 0.0 3.2 3 0 0 3 3 3 2 Poliovirus 3A protein like NAD_binding_4 PF07993.12 KPA36702.1 - 7e-40 136.8 0.0 1.1e-39 136.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KPA36702.1 - 4.5e-15 55.2 0.0 2.4e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KPA36702.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA36702.1 - 1.4e-07 30.8 0.0 2.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 KPA36702.1 - 3.5e-05 24.1 0.0 0.00011 22.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KPA36702.1 - 0.00063 19.2 0.0 0.0028 17.1 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KPA36702.1 - 0.00075 18.7 0.0 0.025 13.7 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 KPA36702.1 - 0.00088 19.2 0.0 0.1 12.5 0.0 2.9 2 1 0 2 2 2 1 KR domain Pyr_redox_2 PF07992.14 KPA36703.1 - 5.1e-15 55.5 0.0 1.7e-13 50.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPA36703.1 - 5.3e-06 25.8 0.1 0.00019 20.6 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KPA36703.1 - 0.00015 21.1 1.6 0.056 12.7 0.7 3.0 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA36703.1 - 0.00022 20.4 0.1 0.038 13.1 0.2 2.2 1 1 1 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KPA36703.1 - 0.00041 19.7 0.4 0.00069 19.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KPA36703.1 - 0.00043 20.3 0.3 0.92 9.5 0.0 2.4 1 1 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KPA36703.1 - 0.00093 18.0 0.1 0.0033 16.2 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KPA36703.1 - 0.0011 18.6 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KPA36703.1 - 0.0012 18.1 0.0 0.37 9.9 0.0 2.4 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPA36703.1 - 0.0026 18.0 0.0 0.015 15.5 0.0 2.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPA36703.1 - 0.003 16.8 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KPA36703.1 - 0.0066 15.5 0.2 0.03 13.4 0.2 1.9 1 1 1 2 2 2 1 Lycopene cyclase protein Amidase_2 PF01510.25 KPA36703.1 - 0.018 15.5 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase FAD_oxidored PF12831.7 KPA36703.1 - 0.092 12.1 0.3 0.15 11.3 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Helo_like_N PF17111.5 KPA36704.1 - 5.7e-68 228.4 0.1 1.4e-67 227.1 0.1 1.6 1 1 1 2 2 2 2 Fungal N-terminal domain of STAND proteins Med9 PF07544.13 KPA36704.1 - 0.0079 16.3 1.4 1.5 8.9 0.0 3.4 4 0 0 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 Phage_int_SAM_2 PF12834.7 KPA36704.1 - 0.038 14.7 0.0 0.098 13.4 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal KASH_CCD PF14662.6 KPA36704.1 - 0.28 11.0 3.2 0.52 10.1 0.0 2.3 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TolA_bind_tri PF16331.5 KPA36704.1 - 1.6 8.8 4.8 5.2 7.2 0.1 2.9 3 0 0 3 3 3 0 TolA binding protein trimerisation MFS_1 PF07690.16 KPA36706.1 - 2.5e-18 66.1 28.1 2.5e-18 66.1 28.1 2.7 1 1 2 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA36706.1 - 1.6e-10 40.4 3.6 1.6e-10 40.4 3.6 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter FAA_hydrolase PF01557.18 KPA36707.1 - 6e-55 186.3 0.0 7.8e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KPA36707.1 - 5.2e-23 81.3 0.0 1.5e-22 79.8 0.0 1.8 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal AIF_C PF14721.6 KPA36710.1 - 2.9 8.3 6.4 5.2 7.4 6.4 1.5 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term BHD_3 PF10405.9 KPA36711.1 - 0.12 12.8 0.4 0.81 10.1 0.1 2.1 1 1 1 2 2 2 0 Rad4 beta-hairpin domain 3 Glyco_transf_28 PF03033.20 KPA36712.1 - 3.2e-24 85.5 0.0 6.3e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KPA36712.1 - 0.0011 17.9 0.0 0.0024 16.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase zf-Tim10_DDP PF02953.15 KPA36712.1 - 0.016 14.8 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Tim10/DDP family zinc finger DUF3632 PF12311.8 KPA36713.1 - 8.4e-43 146.8 5.0 1.2e-42 146.3 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.20 KPA36714.1 - 3e-09 37.5 0.2 4.2e-09 37.0 0.2 1.2 1 0 0 1 1 1 1 ribonuclease Glyco_hydro_114 PF03537.13 KPA36715.1 - 9.6e-83 277.0 0.6 1.1e-82 276.8 0.6 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Bac_rhamnosid_C PF17390.2 KPA36717.1 - 8.6e-11 41.5 1.1 1.6e-10 40.6 0.3 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 KPA36717.1 - 6.8e-08 32.1 0.0 1.8e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF1080 PF06439.11 KPA36717.1 - 9.2e-05 22.6 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Glyco_transf_28 PF03033.20 KPA36718.1 - 9.9e-22 77.5 0.0 3.3e-21 75.8 0.0 2.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KPA36718.1 - 0.00087 18.2 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KPA36718.1 - 0.0014 18.9 0.1 0.034 14.5 0.0 2.7 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 KPA36718.1 - 0.11 12.2 0.3 0.22 11.3 0.3 1.4 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal GST_N PF02798.20 KPA36719.1 - 5.9e-18 65.0 0.0 1.1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPA36719.1 - 2.3e-13 50.4 0.0 5e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPA36719.1 - 2.6e-12 46.9 0.0 1.7e-11 44.3 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPA36719.1 - 1.1e-09 38.4 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA36719.1 - 1.5e-09 37.9 0.0 2.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPA36719.1 - 1.6e-07 31.2 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RuBisCO_small PF00101.20 KPA36719.1 - 0.4 10.7 1.8 0.45 10.5 0.2 1.8 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain GFO_IDH_MocA PF01408.22 KPA36720.1 - 3e-19 70.0 0.1 5.3e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_43 PF04616.14 KPA36721.1 - 1.2e-52 179.1 5.5 1.4e-52 178.8 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KPA36721.1 - 0.0036 16.9 1.0 0.012 15.2 0.5 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 KPA36722.1 - 2e-54 184.8 3.8 2.5e-54 184.6 3.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KPA36722.1 - 0.00019 21.1 1.5 0.00019 21.1 1.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Phage_holin_2_3 PF16080.5 KPA36723.1 - 1.6 8.5 5.2 2.1 8.2 0.4 2.6 1 1 1 2 2 2 0 Bacteriophage holin family HP1 Transferase PF02458.15 KPA36724.1 - 3e-05 22.9 0.0 4.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Transferase family MFS_1 PF07690.16 KPA36725.1 - 1.7e-34 119.3 32.3 1.7e-34 119.3 32.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.21 KPA36725.1 - 0.0031 16.4 4.0 0.0071 15.2 4.0 1.5 1 0 0 1 1 1 1 POT family Cytochrome-c551 PF10643.9 KPA36725.1 - 3.2 7.3 7.5 0.42 10.2 1.7 2.2 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Zn_clus PF00172.18 KPA36726.1 - 1e-07 31.9 8.9 1.7e-07 31.2 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA36726.1 - 3.4e-06 26.1 1.8 1.3e-05 24.3 1.8 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Arc PF03869.14 KPA36727.1 - 0.1 12.4 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Arc-like DNA binding domain Sugar_tr PF00083.24 KPA36729.1 - 2.4e-91 306.9 16.0 3e-91 306.6 16.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36729.1 - 4.2e-23 81.8 35.1 6.5e-16 58.2 13.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KPA36729.1 - 0.0027 16.1 7.1 0.26 9.5 0.1 3.1 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family CD225 PF04505.12 KPA36729.1 - 2.6 8.3 5.7 0.47 10.6 0.9 2.4 2 0 0 2 2 2 0 Interferon-induced transmembrane protein MatE PF01554.18 KPA36730.1 - 5.1e-55 185.5 29.5 4.1e-33 114.3 9.7 2.4 2 0 0 2 2 2 2 MatE Abhydrolase_3 PF07859.13 KPA36730.1 - 2.9e-24 86.1 0.0 1.9e-22 80.2 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPA36730.1 - 2.3e-05 23.5 0.0 3.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Ank_2 PF12796.7 KPA36732.1 - 1.2e-43 147.6 6.7 2.3e-12 47.3 0.0 8.2 5 2 7 12 12 12 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA36732.1 - 2.9e-26 88.6 9.9 0.036 14.6 0.0 14.2 14 0 0 14 14 14 6 Ankyrin repeat Ank_4 PF13637.6 KPA36732.1 - 2.6e-25 88.5 17.3 3.1e-06 27.6 0.0 10.0 9 1 1 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA36732.1 - 2.9e-22 78.4 15.2 1.3e-05 25.3 0.1 8.3 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KPA36732.1 - 8.3e-18 64.0 11.0 0.032 14.7 0.0 10.6 12 0 0 12 12 12 4 Ankyrin repeat DUF676 PF05057.14 KPA36732.1 - 7.5e-05 22.3 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Nucleoporin_FG PF13634.6 KPA36733.1 - 3.7e-05 24.5 11.6 3.7e-05 24.5 11.6 2.5 2 1 0 2 2 2 1 Nucleoporin FG repeat region TPR_10 PF13374.6 KPA36734.1 - 1.8e-50 167.5 22.3 3.1e-12 46.0 0.6 7.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 KPA36734.1 - 4.8e-38 129.3 16.0 1.1e-12 48.0 0.1 5.0 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KPA36734.1 - 1.8e-11 43.3 5.9 0.0013 18.7 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KPA36734.1 - 5.5e-08 32.4 7.3 0.038 14.2 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KPA36734.1 - 1.6e-07 30.9 2.5 0.022 14.6 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPA36734.1 - 4.1e-07 29.6 15.7 0.021 14.8 0.1 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 KPA36734.1 - 8.5e-06 25.9 5.3 0.054 14.1 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KPA36734.1 - 6.8e-05 22.4 6.2 0.022 14.1 3.0 2.8 1 1 0 2 2 2 2 MalT-like TPR region TPR_17 PF13431.6 KPA36734.1 - 7.6e-05 22.8 2.2 1.3 9.6 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 KPA36734.1 - 8.4e-05 22.5 0.0 0.12 12.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KPA36734.1 - 0.00012 22.5 8.1 3.9 8.0 0.1 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPA36734.1 - 0.009 16.6 0.2 2.3 9.0 0.1 4.1 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPA36734.1 - 0.036 14.9 7.5 1.9 9.6 0.1 5.3 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPA36734.1 - 0.038 14.6 6.5 0.76 10.6 0.1 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat PPR PF01535.20 KPA36734.1 - 0.32 11.3 3.5 6.7 7.2 0.0 4.4 5 0 0 5 5 4 0 PPR repeat Sugar_tr PF00083.24 KPA36735.1 - 3.1e-16 59.3 4.4 3.4e-16 59.2 4.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36735.1 - 3.2e-07 29.6 5.7 3.5e-07 29.5 5.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.7 KPA36735.1 - 2.3 8.4 9.1 0.48 10.6 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) RTA1 PF04479.13 KPA36736.1 - 3.1e-66 222.9 13.9 4.6e-66 222.4 13.9 1.3 1 0 0 1 1 1 1 RTA1 like protein HlyIII PF03006.20 KPA36736.1 - 0.00024 20.9 2.5 0.00024 20.9 2.5 2.2 1 1 0 2 2 2 1 Haemolysin-III related GMC_oxred_N PF00732.19 KPA36737.1 - 5.5e-47 160.6 0.0 7.5e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA36737.1 - 2.1e-35 122.3 0.0 3.4e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPA36737.1 - 4.2e-05 22.8 1.2 0.016 14.3 1.5 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KPA36737.1 - 6.1e-05 22.4 1.8 0.0023 17.2 0.7 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA36737.1 - 0.021 14.4 1.4 3.1 7.3 1.9 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA36737.1 - 0.028 13.7 3.4 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA36737.1 - 0.093 13.0 2.1 0.28 11.4 2.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MazG-like PF12643.7 KPA36739.1 - 1.7e-20 73.1 0.2 3.2e-20 72.2 0.0 1.5 2 0 0 2 2 2 1 MazG-like family MazG PF03819.17 KPA36739.1 - 6.2e-05 23.1 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain dUTPase_2 PF08761.11 KPA36739.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 dUTPase PRA-PH PF01503.17 KPA36739.1 - 0.073 13.5 0.1 0.095 13.2 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase Pkinase PF00069.25 KPA36740.1 - 2.5e-07 30.4 0.0 3.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA36740.1 - 3.6e-06 26.5 0.0 5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MRP-S25 PF13741.6 KPA36740.1 - 0.057 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 DUF3619 PF12279.8 KPA36740.1 - 0.093 13.1 0.2 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) DUF2300 PF10062.9 KPA36740.1 - 0.3 11.2 1.0 0.8 9.8 0.4 1.9 1 1 1 2 2 2 0 Predicted secreted protein (DUF2300) Pkinase PF00069.25 KPA36741.1 - 1.6e-20 73.6 0.0 1.9e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA36741.1 - 1e-11 44.6 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPA36741.1 - 0.046 13.1 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp PF00026.23 KPA36743.1 - 1e-24 87.5 0.0 1.6e-24 86.9 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA36743.1 - 0.00017 21.9 0.2 0.012 15.8 0.0 3.1 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPA36743.1 - 0.092 13.4 0.4 2.4 8.9 0.0 2.8 2 1 0 2 2 2 0 Aspartyl protease Pec_lyase_C PF00544.19 KPA36744.1 - 5.3e-44 150.3 4.7 7.5e-44 149.8 4.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KPA36744.1 - 0.00033 20.5 9.4 0.0011 18.9 9.2 1.9 1 1 0 1 1 1 1 Right handed beta helix region PSI_PsaH PF03244.14 KPA36744.1 - 0.054 13.0 0.1 0.16 11.5 0.1 1.8 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI Trypsin PF00089.26 KPA36746.1 - 3e-64 216.9 4.2 3.4e-64 216.7 4.2 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KPA36746.1 - 4.9e-11 43.7 4.2 6.9e-11 43.3 4.2 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KPA36746.1 - 0.073 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Helo_like_N PF17111.5 KPA36747.1 - 0.0054 16.1 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_30 PF13604.6 KPA36747.1 - 0.0095 15.7 0.1 0.03 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPA36747.1 - 0.068 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KPA36747.1 - 0.073 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KPA36747.1 - 0.091 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_13 PF13166.6 KPA36747.1 - 0.2 10.3 0.0 7.3 5.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRP-alpha_N PF04086.13 KPA36749.1 - 0.26 11.2 6.5 0.4 10.6 6.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Helitron_like_N PF14214.6 KPA36750.1 - 2.8e-13 50.5 1.2 6.2e-13 49.4 0.1 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus DUF3638 PF12340.8 KPA36751.1 - 3.3e-97 324.3 0.9 7.9e-97 323.0 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KPA36751.1 - 1.8e-18 65.6 0.5 3.8e-18 64.6 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Sugar_tr PF00083.24 KPA36752.1 - 2.1e-109 366.4 20.6 2.4e-109 366.2 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36752.1 - 1.7e-24 86.4 35.3 1.4e-21 76.8 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YrhK PF14145.6 KPA36752.1 - 0.4 10.6 7.8 0.99 9.3 0.8 2.7 2 0 0 2 2 2 0 YrhK-like protein AA_permease PF00324.21 KPA36753.1 - 8.8e-136 453.3 35.4 1.1e-135 453.0 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA36753.1 - 8.9e-41 140.1 39.5 1.2e-40 139.7 39.5 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_S15 PF02129.18 KPA36754.1 - 2.8e-43 148.4 3.4 2.9e-37 128.7 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KPA36754.1 - 5.9e-34 118.0 0.0 8e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DUF1479 PF07350.12 KPA36755.1 - 4.6e-05 22.4 0.0 0.029 13.1 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.13 KPA36755.1 - 0.00014 22.2 0.2 0.00034 20.9 0.2 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KPA36755.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase BCS1_N PF08740.11 KPA36756.1 - 1.5e-18 67.5 0.1 2.6e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KPA36756.1 - 8.8e-18 65.0 0.0 1.9e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPA36756.1 - 0.0014 19.0 0.0 0.0062 16.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KPA36756.1 - 0.0064 16.1 0.1 0.029 13.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KPA36756.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KPA36756.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KPA36756.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KPA36756.1 - 0.086 13.1 0.6 5.7 7.2 0.1 2.5 1 1 1 2 2 2 0 AAA domain PPV_E1_C PF00519.17 KPA36756.1 - 0.091 11.6 0.0 0.21 10.4 0.0 1.5 2 0 0 2 2 2 0 Papillomavirus helicase AAA_5 PF07728.14 KPA36756.1 - 0.11 12.5 0.1 1.6 8.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KPA36756.1 - 0.15 12.5 0.0 3.9 7.9 0.0 2.6 2 1 0 2 2 2 0 RNA helicase HET PF06985.11 KPA36757.1 - 3.4e-26 92.3 0.0 5.9e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 KPA36758.1 - 3.1e-11 43.5 0.1 6.9e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KPA36758.1 - 4.4e-08 33.5 0.1 1.5e-07 31.8 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA36758.1 - 2.2e-06 28.2 0.5 9.2e-06 26.1 0.4 2.1 2 0 0 2 2 2 1 AAA ATPase domain PNP_UDP_1 PF01048.20 KPA36758.1 - 1.1e-05 24.8 0.2 3.4e-05 23.2 0.2 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_14 PF13173.6 KPA36758.1 - 3.1e-05 24.0 0.0 0.0074 16.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KPA36758.1 - 0.0009 18.6 0.1 0.41 9.8 0.1 2.2 1 1 1 2 2 2 2 KAP family P-loop domain ATPase_2 PF01637.18 KPA36758.1 - 0.0031 17.5 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KPA36758.1 - 0.046 12.9 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KPA36758.1 - 0.056 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KPA36758.1 - 0.12 12.8 0.1 1.4 9.4 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ribonuclease_T2 PF00445.18 KPA36759.1 - 6.3e-14 52.6 0.0 1.6e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease T2 family FAD_binding_4 PF01565.23 KPA36760.1 - 6.8e-12 45.3 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPA36760.1 - 2.3e-07 30.8 0.4 5e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like Amidase PF01425.21 KPA36761.1 - 7.1e-88 295.5 0.0 8.6e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Amidase Inos-1-P_synth PF01658.17 KPA36761.1 - 0.013 15.7 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase adh_short PF00106.25 KPA36762.1 - 4.7e-36 124.1 0.0 9.8e-36 123.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA36762.1 - 3.3e-24 85.7 0.0 9.1e-24 84.3 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA36762.1 - 1.5e-06 28.3 0.0 2.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA36762.1 - 0.0011 18.5 0.0 0.0045 16.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KPA36762.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 KPA36762.1 - 0.0063 16.5 0.0 0.032 14.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KPA36762.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 2 0 0 2 2 2 0 NAD(P)H-binding DUF2007 PF09413.10 KPA36762.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein RmlD_sub_bind PF04321.17 KPA36762.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain His_Phos_2 PF00328.22 KPA36763.1 - 4.2e-28 98.8 0.0 5.3e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Etmic-2 PF06670.11 KPA36763.1 - 0.14 11.1 0.2 0.21 10.5 0.2 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 Acetyltransf_3 PF13302.7 KPA36764.1 - 2.4e-16 60.7 0.1 3e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4267 PF14087.6 KPA36765.1 - 1.4e-16 60.5 0.2 1.7e-16 60.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Hexapep PF00132.24 KPA36766.1 - 2.9e-15 55.3 11.7 7.4e-12 44.5 4.1 4.0 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KPA36766.1 - 2.6e-14 53.2 0.0 4.1e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 KPA36766.1 - 3.9e-14 52.1 11.7 2.4e-11 43.2 3.8 3.4 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase EHN PF06441.12 KPA36770.1 - 1.7e-29 102.4 0.4 2.2e-29 102.0 0.4 1.1 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPA36770.1 - 5.5e-09 36.0 0.0 8.8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Aminotran_4 PF01063.19 KPA36771.1 - 1.3e-37 129.8 0.0 1.6e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Peptidase_M16_C PF05193.21 KPA36772.1 - 6e-17 62.3 0.0 2.1e-13 50.7 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KPA36772.1 - 2.2e-06 27.7 0.0 6.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KPA36772.1 - 0.065 12.4 1.6 7.4 5.6 0.8 3.1 3 0 0 3 3 3 0 Peptidase M16C associated adh_short PF00106.25 KPA36775.1 - 4e-41 140.6 0.0 4.9e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA36775.1 - 9.4e-23 81.0 0.0 1.3e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA36775.1 - 2.1e-08 34.3 0.0 2.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KPA36775.1 - 0.00086 19.8 0.2 0.0017 18.9 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KPA36775.1 - 0.00098 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA36775.1 - 0.0043 16.5 0.1 0.0066 15.9 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KPA36775.1 - 0.0065 15.6 0.0 0.0097 15.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KPA36775.1 - 0.028 14.5 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KPA36775.1 - 0.099 12.9 0.2 0.2 11.9 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_25 PF13649.6 KPA36776.1 - 4.7e-18 65.7 0.0 9.6e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA36776.1 - 1.2e-15 57.6 0.0 2.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA36776.1 - 7.8e-14 52.1 0.0 1.5e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA36776.1 - 8.9e-13 48.4 0.0 1.9e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA36776.1 - 6.9e-12 46.0 0.0 1.3e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA36776.1 - 1.6e-08 34.3 0.0 2.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 KPA36776.1 - 3.7e-05 23.3 0.0 0.0032 17.0 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 KPA36776.1 - 4.9e-05 23.5 0.0 8.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.14 KPA36776.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KPA36776.1 - 0.0002 21.2 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KPA36776.1 - 0.00028 20.4 0.0 0.0006 19.3 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 KPA36776.1 - 0.00086 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 KPA36776.1 - 0.0041 17.1 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KPA36776.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KPA36776.1 - 0.065 12.6 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KPA36776.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3176 PF11374.8 KPA36777.1 - 6.4e-33 113.2 0.3 6.4e-33 113.2 0.3 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3176) KDGP_aldolase PF07071.11 KPA36777.1 - 0.002 18.0 0.1 0.0041 17.0 0.1 1.4 1 0 0 1 1 1 1 KDGP aldolase Omega-toxin PF06357.11 KPA36777.1 - 0.14 12.0 0.4 0.34 10.7 0.4 1.6 1 0 0 1 1 1 0 Omega-atracotoxin CFEM PF05730.11 KPA36778.1 - 0.00087 19.3 4.8 0.0016 18.5 4.8 1.4 1 0 0 1 1 1 1 CFEM domain Thr_synth_N PF14821.6 KPA36779.1 - 8.4e-27 93.2 0.0 2.1e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KPA36779.1 - 2.5e-17 63.2 0.0 8.5e-17 61.5 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GRP PF07172.11 KPA36781.1 - 1.3 9.7 9.9 0.077 13.7 4.1 1.9 2 1 0 2 2 2 0 Glycine rich protein family Epiglycanin_TR PF05647.11 KPA36782.1 - 2.9 7.9 9.2 2 8.4 4.9 2.3 1 1 1 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like Cellulase PF00150.18 KPA36785.1 - 3e-17 62.9 3.7 7.4e-17 61.7 3.7 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NACHT PF05729.12 KPA36786.1 - 1.5e-07 31.5 0.0 3.1e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPA36786.1 - 1.5e-06 28.7 0.2 3.1e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KPA36786.1 - 0.0014 18.5 0.1 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KPA36786.1 - 0.004 17.7 0.0 0.013 16.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter DUF2075 PF09848.9 KPA36786.1 - 0.015 14.5 0.4 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.7 KPA36786.1 - 0.033 13.1 0.1 0.086 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain KAP_NTPase PF07693.14 KPA36786.1 - 0.041 13.1 0.3 5.1 6.2 0.2 2.7 2 1 1 3 3 3 0 KAP family P-loop domain AAA_22 PF13401.6 KPA36786.1 - 0.087 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KPA36786.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KPA36786.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region FF PF01846.19 KPA36786.1 - 0.15 12.3 0.2 7 6.9 0.0 3.1 3 0 0 3 3 3 0 FF domain BTB PF00651.31 KPA36787.1 - 0.0089 16.2 0.3 0.024 14.9 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Fungal_trans PF04082.18 KPA36788.1 - 6.1e-14 51.7 0.4 1.2e-13 50.7 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.31 KPA36792.1 - 6.1e-12 45.7 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain PNP_UDP_1 PF01048.20 KPA36793.1 - 3e-05 23.4 0.6 8e-05 22.0 0.6 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily ADH_zinc_N PF00107.26 KPA36794.1 - 1e-20 74.0 2.3 1.6e-20 73.4 2.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA36794.1 - 2.5e-17 62.7 1.7 2.5e-17 62.7 1.7 3.0 2 2 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPA36794.1 - 8.8e-06 26.8 0.0 1.7e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 KPA36794.1 - 0.0041 17.3 0.8 0.0075 16.5 0.8 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KPA36794.1 - 0.015 14.6 0.4 0.027 13.8 0.4 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HHH_2 PF12826.7 KPA36794.1 - 0.032 14.3 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF2855 PF11017.8 KPA36794.1 - 0.16 11.7 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) AlaDh_PNT_C PF01262.21 KPA36794.1 - 5.1 6.3 9.8 0.6 9.4 4.4 1.9 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 KPA36795.1 - 6.8e-20 71.0 0.3 1.4e-17 63.4 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPA36795.1 - 3.9e-16 59.1 0.0 7.8e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA36795.1 - 1.5e-10 40.8 0.0 6.3e-10 38.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA36795.1 - 1.2e-09 37.8 0.0 3.8e-08 32.9 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPA36795.1 - 1.5e-09 38.0 0.0 7.2e-07 29.3 0.0 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPA36795.1 - 9.6e-07 28.2 0.0 0.00042 19.5 0.1 2.8 2 1 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 KPA36795.1 - 3.2e-05 23.7 0.1 0.021 14.4 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA36795.1 - 3.2e-05 24.4 0.7 0.19 12.3 0.1 3.5 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA36795.1 - 0.00053 20.0 0.4 1.1 9.2 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KPA36795.1 - 0.00054 19.2 0.0 0.0009 18.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPA36795.1 - 0.0013 17.5 0.8 0.026 13.3 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.20 KPA36795.1 - 0.0055 16.8 0.0 1.7 8.7 0.0 2.6 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KPA36795.1 - 0.0065 15.7 0.0 0.016 14.4 0.0 1.6 1 0 0 1 1 1 1 Thi4 family 2-Hacid_dh_C PF02826.19 KPA36795.1 - 0.013 14.9 0.1 0.39 10.0 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KPA36795.1 - 0.03 14.8 0.0 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KPA36795.1 - 0.1 11.8 0.2 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KPA36795.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase DDE_1 PF03184.19 KPA36797.1 - 7.9e-23 81.0 0.0 2e-22 79.7 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 KPA36797.1 - 0.0027 17.5 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HET PF06985.11 KPA36798.1 - 2.6e-30 105.7 0.0 1.4e-21 77.4 0.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4379 PF14311.6 KPA36798.1 - 0.13 12.6 5.5 11 6.4 0.7 3.4 2 2 0 2 2 2 0 Probable Zinc-ribbon domain Apidaecin PF00807.17 KPA36798.1 - 7.9 6.7 8.9 22 5.2 1.2 2.4 2 0 0 2 2 2 0 Apidaecin His_Phos_1 PF00300.22 KPA36799.1 - 0.0004 20.1 0.0 0.00047 19.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DNA_pol_B_thumb PF14791.6 KPA36799.1 - 0.015 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase beta thumb Cutinase PF01083.22 KPA36800.1 - 2.6e-07 30.8 0.0 2.6e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Cutinase DUF5585 PF17823.1 KPA36800.1 - 0.01 14.9 20.7 0.012 14.7 20.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Big_3_3 PF13750.6 KPA36800.1 - 0.24 11.1 4.5 0.35 10.5 4.5 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Cutinase PF01083.22 KPA36801.1 - 6.3e-14 52.3 0.0 7.9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPA36801.1 - 0.0034 16.9 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KPA36801.1 - 0.096 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF2235 PF09994.9 KPA36802.1 - 8.7e-86 287.8 2.1 7.9e-85 284.7 2.1 2.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) IFT46_B_C PF12317.8 KPA36802.1 - 0.33 10.7 0.7 0.57 9.9 0.7 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal T3SS_needle_reg PF09025.10 KPA36803.1 - 0.016 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator MFS_1 PF07690.16 KPA36804.1 - 1.5e-29 103.0 36.5 1.9e-29 102.7 36.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1129 PF06570.11 KPA36804.1 - 0.23 10.9 2.5 4.7 6.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF829 PF05705.14 KPA36805.1 - 3.7e-30 105.6 0.1 4.8e-30 105.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Methyltransf_23 PF13489.6 KPA36806.1 - 1.3e-21 77.1 0.0 1.9e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA36806.1 - 2.2e-11 44.3 0.0 4.6e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA36806.1 - 4e-09 36.5 0.0 9.5e-08 32.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA36806.1 - 1e-07 32.5 0.0 2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA36806.1 - 9e-07 29.6 0.0 1.1e-05 26.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KPA36806.1 - 0.00015 22.0 0.0 0.00028 21.0 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KPA36806.1 - 0.00027 20.4 0.5 0.0012 18.3 0.0 2.2 3 0 0 3 3 3 1 Putative methyltransferase CMAS PF02353.20 KPA36806.1 - 0.0045 16.3 0.0 0.016 14.5 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KPA36806.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KPA36806.1 - 0.036 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KPA36806.1 - 0.065 13.0 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KPA36806.1 - 0.12 11.6 0.0 3.1 7.0 0.0 2.4 3 0 0 3 3 3 0 O-methyltransferase domain CheR PF01739.18 KPA36807.1 - 0.00015 21.3 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.6 KPA36807.1 - 0.00035 20.5 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA36807.1 - 0.00044 20.9 0.0 0.0008 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA36807.1 - 0.0016 19.2 0.0 0.0044 17.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA36807.1 - 0.0098 15.7 0.0 0.064 13.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA36807.1 - 0.05 14.2 0.0 0.09 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CFEM PF05730.11 KPA36808.1 - 0.00012 22.1 11.7 0.00012 22.1 11.7 1.5 1 1 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 KPA36808.1 - 0.0031 17.7 4.4 0.0031 17.7 4.4 2.3 2 0 0 2 2 2 1 Gamma-thionin family Solute_trans_a PF03619.16 KPA36809.1 - 3.8e-55 187.3 15.7 4.7e-55 187.0 15.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SUR7 PF06687.12 KPA36809.1 - 0.13 11.9 8.5 0.34 10.5 2.1 2.3 2 0 0 2 2 2 0 SUR7/PalI family F-box-like PF12937.7 KPA36810.1 - 4.3e-07 29.7 1.0 4.3e-07 29.7 1.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KPA36810.1 - 0.0014 18.5 1.2 0.0042 16.9 1.2 1.9 1 0 0 1 1 1 1 F-box domain APH PF01636.23 KPA36811.1 - 7.4e-12 45.7 0.0 1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KPA36811.1 - 2e-05 23.6 0.0 2.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KPA36811.1 - 8.6e-05 22.0 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KPA36811.1 - 0.0046 16.6 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KPA36811.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KPA36813.1 - 3.3e-16 59.4 0.0 4.6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA36813.1 - 4e-09 36.1 0.0 5.7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPA36813.1 - 3e-07 30.0 0.0 4.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPA36813.1 - 7.1e-05 22.8 0.1 0.00011 22.3 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPA36813.1 - 0.0021 17.7 0.1 0.0036 16.9 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KPA36813.1 - 0.007 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KPA36814.1 - 2.3e-05 23.9 0.1 4.4e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Radial_spoke_3 PF06098.11 KPA36814.1 - 0.057 12.7 8.2 0.044 13.1 6.6 1.6 2 0 0 2 2 2 0 Radial spoke protein 3 Kdo PF06293.14 KPA36814.1 - 0.057 12.8 0.5 0.11 11.9 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPA36814.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 KPA36816.1 - 1.2e-78 265.1 23.4 1.4e-78 264.8 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36816.1 - 1.9e-22 79.7 23.3 1.9e-22 79.7 23.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NDUF_B12 PF08122.12 KPA36816.1 - 0.1 12.7 0.0 25 5.0 0.0 3.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family FAD_binding_4 PF01565.23 KPA36817.1 - 3.8e-20 72.0 0.5 9.3e-20 70.8 0.2 1.9 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 KPA36817.1 - 2.6e-09 37.0 0.1 5.5e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like WSC PF01822.19 KPA36819.1 - 3.2e-39 133.0 46.6 8.2e-13 48.4 8.1 5.4 5 0 0 5 5 5 5 WSC domain Aa_trans PF01490.18 KPA36821.1 - 4.3e-52 177.2 35.8 4.9e-52 177.0 35.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UNC-93 PF05978.16 KPA36823.1 - 3.1e-07 30.2 3.7 3.1e-07 30.2 3.7 2.2 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KPA36823.1 - 1.8e-05 23.9 28.9 6.3e-05 22.1 27.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.21 KPA36824.1 - 1.9e-36 125.8 0.0 1.8e-29 102.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Acyl_transf_3 PF01757.22 KPA36825.1 - 3.8e-16 59.1 17.1 4.9e-16 58.7 17.1 1.0 1 0 0 1 1 1 1 Acyltransferase family DUF418 PF04235.12 KPA36825.1 - 0.0023 17.9 6.4 0.004 17.1 4.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF418) MFS_1 PF07690.16 KPA36826.1 - 9.8e-40 136.5 35.8 9.8e-40 136.5 35.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA36826.1 - 0.00013 20.6 2.7 0.00021 19.9 2.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.9 KPA36826.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_88 PF07470.13 KPA36827.1 - 3.1e-66 223.8 12.2 3.8e-66 223.5 12.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KPA36827.1 - 0.0051 15.4 0.8 0.012 14.2 0.5 1.4 1 1 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Kelch_4 PF13418.6 KPA36828.1 - 1.5e-21 76.1 3.5 5.5e-07 29.5 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KPA36828.1 - 5.2e-20 71.2 2.4 1.4e-05 25.3 0.0 6.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KPA36828.1 - 2.4e-18 65.7 0.2 0.00013 21.9 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 KPA36828.1 - 2.7e-12 46.5 0.2 0.011 15.9 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KPA36828.1 - 3.6e-11 42.5 0.0 0.0064 16.0 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 KPA36828.1 - 6.1e-06 26.0 0.3 0.059 13.4 0.0 4.2 4 0 0 4 4 4 1 Kelch motif MFS_1 PF07690.16 KPA36829.1 - 1.3e-17 63.7 39.7 2.2e-15 56.4 37.9 3.3 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KPA36829.1 - 4.6e-05 21.9 17.4 0.00012 20.5 0.9 3.1 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KPA36829.1 - 0.00023 19.7 5.2 0.00047 18.7 3.0 2.4 2 1 0 2 2 2 1 Transmembrane secretion effector Pam17 PF08566.10 KPA36829.1 - 0.15 11.9 0.1 0.51 10.2 0.1 1.9 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.16 KPA36830.1 - 2e-49 168.4 40.0 2e-49 168.4 40.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA36830.1 - 2.3e-13 49.8 9.1 2.3e-13 49.8 9.1 3.4 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KPA36830.1 - 0.81 8.0 14.7 0.11 10.9 9.9 2.0 1 1 1 2 2 2 0 Transmembrane secretion effector Deltameth_res PF16020.5 KPA36830.1 - 5.4 7.0 9.7 2.7 7.9 0.2 4.2 3 1 0 4 4 4 0 Deltamethrin resistance Oxidored_FMN PF00724.20 KPA36831.1 - 8.4e-45 153.5 0.0 1.1e-44 153.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KPA36831.1 - 0.005 16.0 0.0 0.043 12.9 0.0 2.1 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) AP_endonuc_2 PF01261.24 KPA36831.1 - 0.011 15.1 0.0 0.26 10.7 0.0 2.5 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel p450 PF00067.22 KPA36832.1 - 2.2e-86 290.5 0.0 2.6e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Takusan PF04822.13 KPA36833.1 - 0.089 12.7 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Takusan DUF3606 PF12244.8 KPA36833.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Pro_CA PF00484.19 KPA36834.1 - 4.5e-11 43.3 0.2 6e-10 39.6 0.2 2.1 1 1 0 1 1 1 1 Carbonic anhydrase SLAC1 PF03595.17 KPA36835.1 - 2.3e-68 230.8 42.6 2.6e-68 230.7 42.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Adeno_E3 PF06040.11 KPA36835.1 - 0.0046 17.1 0.1 0.32 11.2 0.0 2.4 2 0 0 2 2 2 2 Adenovirus E3 protein p450 PF00067.22 KPA36839.1 - 4.4e-72 243.3 0.0 5.3e-72 243.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.21 KPA36840.1 - 5.3e-32 110.7 0.0 9.3e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KPA36840.1 - 2.7e-27 95.0 0.0 4.9e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KPA36840.1 - 1.8e-24 85.6 0.1 3.4e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KPA36840.1 - 0.00086 19.5 0.0 0.012 15.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KPA36840.1 - 0.015 15.5 0.0 0.063 13.5 0.0 1.9 1 1 0 1 1 1 0 Siderophore-interacting FAD-binding domain AA_permease_2 PF13520.6 KPA36841.1 - 8.5e-76 255.5 32.2 1.1e-75 255.1 32.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA36841.1 - 1.5e-18 66.7 25.2 2.2e-18 66.1 25.2 1.2 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KPA36841.1 - 0.0092 14.7 11.4 0.065 11.9 11.4 2.2 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Cellulase PF00150.18 KPA36842.1 - 7.3e-28 97.8 0.3 9.1e-28 97.5 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KPA36842.1 - 0.00016 21.5 0.2 0.00018 21.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) L_protein_N PF15518.6 KPA36842.1 - 0.16 11.8 1.0 23 4.9 0.0 2.8 2 1 1 3 3 3 0 L protein N-terminus Sugar_tr PF00083.24 KPA36843.1 - 1.2e-87 294.7 22.4 1.4e-87 294.4 22.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36843.1 - 2.8e-28 98.9 46.0 2e-24 86.2 24.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA36843.1 - 2.5e-07 29.5 2.0 2.5e-07 29.5 2.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KPA36843.1 - 0.022 13.7 7.5 0.34 9.7 5.2 2.6 1 1 1 2 2 2 0 MFS_1 like family But2 PF09792.9 KPA36844.1 - 0.0018 18.7 0.1 0.0069 16.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain UME PF08064.13 KPA36845.1 - 0.23 11.4 0.9 11 6.0 0.4 3.0 2 0 0 2 2 2 0 UME (NUC010) domain Amidase PF01425.21 KPA36846.1 - 1.1e-91 308.1 0.0 1.2e-90 304.6 0.0 1.9 1 1 0 1 1 1 1 Amidase BLM_N PF16202.5 KPA36846.1 - 0.18 10.9 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein MFS_1 PF07690.16 KPA36847.1 - 4.5e-25 88.3 23.5 2.4e-13 49.7 8.4 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 KPA36847.1 - 0.013 14.9 7.8 0.037 13.3 2.0 2.7 2 1 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB DUF5392 PF17370.2 KPA36847.1 - 0.17 12.0 0.0 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5392) FAD-oxidase_C PF02913.19 KPA36848.1 - 3.7e-55 187.3 1.6 4.6e-55 187.0 0.2 1.8 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KPA36848.1 - 4.1e-36 123.8 0.0 7.7e-36 122.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 KPA36848.1 - 0.0015 18.6 14.5 0.0029 17.7 14.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANF_receptor PF01094.28 KPA36848.1 - 0.0032 16.6 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Abhydrolase_3 PF07859.13 KPA36849.1 - 1.3e-14 54.6 0.0 1.4e-09 38.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA36849.1 - 6.7e-09 35.5 0.0 3.4e-07 30.0 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 KPA36849.1 - 3.1e-05 23.0 0.0 4.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 KPA36849.1 - 0.00012 21.7 0.0 0.023 14.3 0.0 2.7 3 0 0 3 3 3 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KPA36849.1 - 0.0058 15.6 0.0 0.0091 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 KPA36849.1 - 0.0059 15.3 0.0 0.15 10.7 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KPA36849.1 - 0.023 14.5 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.14 KPA36849.1 - 0.035 13.4 0.0 0.82 8.9 0.1 2.1 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_1 PF00561.20 KPA36849.1 - 0.15 11.7 0.8 19 4.8 0.1 2.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 KPA36849.1 - 0.15 11.6 0.0 1.2 8.7 0.0 2.3 2 1 0 2 2 2 0 Putative esterase Cupin_2 PF07883.11 KPA36850.1 - 9.7e-13 47.6 0.1 3.1e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Ppnp PF06865.11 KPA36850.1 - 9.9e-05 22.7 0.0 0.00038 20.8 0.0 2.0 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase Cupin_3 PF05899.12 KPA36850.1 - 0.0037 16.9 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KPA36850.1 - 0.006 16.5 0.0 0.86 9.5 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase AraC_binding PF02311.19 KPA36850.1 - 0.038 13.9 0.3 0.45 10.4 0.1 2.2 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_4 PF08007.12 KPA36850.1 - 0.047 13.1 0.3 0.38 10.2 0.1 2.0 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_6 PF12852.7 KPA36850.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cupin DSL PF01414.19 KPA36851.1 - 0.076 13.3 0.4 0.1 12.9 0.4 1.2 1 0 0 1 1 1 0 Delta serrate ligand Methyltransf_2 PF00891.18 KPA36852.1 - 2.9e-23 82.3 0.0 4.2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 KPA36852.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 MarR family DHHC PF01529.20 KPA36853.1 - 9.6 6.3 7.6 4.3 7.4 1.1 2.6 2 1 0 2 2 2 0 DHHC palmitoyltransferase GST_C_2 PF13410.6 KPA36854.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA36854.1 - 0.00017 21.7 0.0 0.00034 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPA36854.1 - 0.00057 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPA36854.1 - 0.0015 18.7 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPA36854.1 - 0.0066 16.8 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PI-PLC-X PF00388.19 KPA36855.1 - 1.8e-63 212.4 0.0 3e-63 211.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KPA36855.1 - 1.8e-41 141.1 0.0 2.9e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain T2SSJ PF11612.8 KPA36855.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J MFS_1 PF07690.16 KPA36856.1 - 1.5e-09 37.3 51.5 4.3e-07 29.2 36.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_14 PF08484.11 KPA36856.1 - 0.093 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Sugar_tr PF00083.24 KPA36858.1 - 2.3e-31 109.2 21.2 2.6e-20 72.7 9.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPA36858.1 - 1.5e-13 50.4 10.7 1.5e-13 50.4 10.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 KPA36859.1 - 8e-34 117.4 0.0 8.1e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Pantoate_transf PF02548.15 KPA36859.1 - 0.076 12.4 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Fungal_trans PF04082.18 KPA36860.1 - 1.3e-23 83.5 0.1 1.9e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA36860.1 - 7.2e-09 35.6 6.4 7.2e-09 35.6 6.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3573 PF12097.8 KPA36860.1 - 0.0027 16.6 0.0 0.0071 15.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3573) DUF4349 PF14257.6 KPA36860.1 - 0.57 9.6 3.6 2.5 7.5 1.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) SNF2_N PF00176.23 KPA36861.1 - 0.085 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Toxin_3 PF00537.18 KPA36861.1 - 0.62 10.3 2.7 0.37 11.0 0.6 1.6 2 0 0 2 2 2 0 Scorpion toxin-like domain Spc7_C2 PF15577.6 KPA36863.1 - 0.19 11.8 0.0 0.59 10.2 0.0 1.8 2 0 0 2 2 2 0 Spc7_C2 F-box-like PF12937.7 KPA36864.1 - 1.3e-09 37.8 0.1 5.7e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KPA36864.1 - 0.00013 21.8 1.2 0.00041 20.2 0.1 2.4 3 0 0 3 3 3 1 F-box domain F-box-like_2 PF13013.6 KPA36864.1 - 0.021 14.8 1.0 1.4 8.9 0.2 2.6 2 1 0 2 2 2 0 F-box-like domain Glyco_hydro_10 PF00331.20 KPA36865.1 - 3.8e-104 348.2 0.3 4.3e-104 348.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_1 PF00232.18 KPA36865.1 - 0.027 12.9 0.1 0.056 11.9 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Frankia_peptide PF14407.6 KPA36865.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. GFA PF04828.14 KPA36866.1 - 1.8e-11 44.2 0.0 3.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme TRI5 PF06330.11 KPA36866.1 - 6.9e-11 41.6 0.5 9.2e-11 41.2 0.5 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Nudix_N_2 PF14803.6 KPA36866.1 - 0.088 12.7 0.3 0.19 11.7 0.3 1.5 1 0 0 1 1 1 0 Nudix N-terminal p450 PF00067.22 KPA36867.1 - 7.6e-05 21.6 0.0 9.6e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PfkB PF00294.24 KPA36868.1 - 3.4e-55 187.5 0.0 4.8e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UQ_con PF00179.26 KPA36870.1 - 5.3e-10 39.1 0.0 8.8e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF5314 PF17241.2 KPA36870.1 - 0.022 14.4 0.0 0.065 12.9 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5314) Ccdc124 PF06244.12 KPA36871.1 - 7.2e-29 100.9 21.0 1.4e-27 96.8 21.0 2.1 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 SbsC_C PF18058.1 KPA36871.1 - 0.036 14.3 0.1 0.036 14.3 0.1 2.6 2 1 0 2 2 2 0 SbsC C-terminal domain DUF3235 PF11574.8 KPA36871.1 - 0.74 10.7 0.1 0.74 10.7 0.1 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3235) Bud13 PF09736.9 KPA36871.1 - 9 6.7 23.3 2.1 8.7 15.1 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex JmjC PF02373.22 KPA36874.1 - 5.2e-11 43.0 0.0 1.2e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Peptidase_C48 PF02902.19 KPA36875.1 - 0.00014 21.8 0.1 0.00046 20.1 0.1 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1430 PF07242.11 KPA36876.1 - 0.067 13.5 0.4 0.067 13.5 0.4 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1430) Cu_amine_oxid PF01179.20 KPA36878.1 - 3e-159 530.4 0.0 3.6e-159 530.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KPA36878.1 - 0.00052 20.4 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KPA36878.1 - 0.013 15.7 0.0 0.041 14.1 0.0 1.9 2 0 0 2 2 2 0 Copper amine oxidase, N2 domain DUF4245 PF14030.6 KPA36882.1 - 0.034 14.2 0.1 0.046 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) DUF1682 PF07946.14 KPA36882.1 - 1.5 8.0 6.3 1.9 7.6 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Zn_clus PF00172.18 KPA36883.1 - 1.7e-06 28.0 8.4 3.3e-06 27.1 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA36883.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Tropomyosin PF00261.20 KPA36884.1 - 0.0028 17.1 2.4 0.0028 17.1 2.4 3.4 1 1 2 3 3 3 2 Tropomyosin Fib_alpha PF08702.10 KPA36884.1 - 0.034 14.3 12.5 0.08 13.1 2.7 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF812 PF05667.11 KPA36884.1 - 1.5 7.7 23.4 2.7 6.8 23.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HAP1_N PF04849.13 KPA36884.1 - 3.1 6.9 34.9 0.086 12.0 2.5 3.2 2 1 1 3 3 3 0 HAP1 N-terminal conserved region CRF PF00473.17 KPA36884.1 - 3.3 7.8 5.4 3.8 7.7 2.3 2.6 2 0 0 2 2 2 0 Corticotropin-releasing factor family LMBR1 PF04791.16 KPA36884.1 - 9.9 4.9 6.8 14 4.4 6.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Pyr_redox_2 PF07992.14 KPA36885.1 - 2.5e-51 174.7 2.5 3.5e-51 174.2 2.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KPA36885.1 - 8.3e-15 54.5 0.0 1.9e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KPA36885.1 - 6.7e-13 49.0 1.4 1.8e-11 44.4 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KPA36885.1 - 7.4e-06 26.4 0.0 2.7e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 KPA36885.1 - 1e-05 25.4 0.0 6.1e-05 22.9 0.0 2.2 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.6 KPA36885.1 - 0.0001 21.6 0.0 0.38 9.8 0.0 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPA36885.1 - 0.00063 19.8 0.6 2.9 7.9 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KPA36885.1 - 0.012 16.0 0.8 0.36 11.3 0.0 2.6 3 0 0 3 3 3 0 Putative NAD(P)-binding ADH_N PF08240.12 KPA36886.1 - 2.1e-23 82.3 1.7 3.9e-23 81.4 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA36886.1 - 3.4e-07 30.3 0.0 0.00034 20.6 0.0 2.8 2 1 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KPA36886.1 - 0.038 13.9 0.9 0.038 13.9 0.9 2.0 3 0 0 3 3 3 0 Alcohol dehydrogenase GroES-associated Pyr_redox PF00070.27 KPA36886.1 - 0.39 11.3 1.5 8.5 7.0 0.0 3.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.29 KPA36887.1 - 1.8e-15 57.1 0.0 3.4e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KPA36887.1 - 8.5e-12 45.4 0.0 2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPA36887.1 - 6.6e-08 32.9 0.0 2.1e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Lentivirus_VIF PF05851.11 KPA36887.1 - 0.064 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) OrsD PF12013.8 KPA36888.1 - 2.7e-22 79.4 2.3 9.7e-16 58.2 0.3 2.9 3 0 0 3 3 3 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 KPA36888.1 - 0.1 12.9 2.9 11 6.4 0.0 3.4 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Aldo_ket_red PF00248.21 KPA36889.1 - 7.8e-43 146.7 0.0 8.9e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FMO-like PF00743.19 KPA36890.1 - 9.9e-26 90.2 0.0 4.9e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPA36890.1 - 1.7e-13 50.5 0.0 4.8e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA36890.1 - 5.6e-11 42.2 0.0 7.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA36890.1 - 9.9e-09 34.8 0.0 2.4e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPA36890.1 - 3.2e-06 27.3 0.8 3.2e-05 24.1 0.0 2.9 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPA36890.1 - 6.7e-05 22.9 0.0 0.0015 18.5 0.0 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 KPA36890.1 - 0.0003 20.5 0.0 0.8 9.2 0.0 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA36890.1 - 0.034 14.7 0.0 8.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPA36890.1 - 0.034 13.4 0.0 0.27 10.5 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase p450 PF00067.22 KPA36891.1 - 3.2e-66 224.0 0.0 3.7e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Smim3 PF17307.2 KPA36891.1 - 0.043 13.3 0.4 0.091 12.3 0.4 1.5 1 0 0 1 1 1 0 Small integral membrane protein 3 p450 PF00067.22 KPA36892.1 - 9.1e-51 173.0 0.0 1.3e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Beta-lactamase PF00144.24 KPA36893.1 - 4.1e-21 75.6 0.6 4.7e-20 72.1 0.6 2.0 1 1 0 1 1 1 1 Beta-lactamase Cutinase PF01083.22 KPA36894.1 - 1.6e-40 139.0 0.0 1.8e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPA36894.1 - 0.001 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KPA36894.1 - 0.03 14.2 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 KPA36894.1 - 0.041 13.7 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 KPA36894.1 - 0.087 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FMO-like PF00743.19 KPA36895.1 - 5.4e-17 61.4 0.6 4.2e-14 51.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPA36895.1 - 4.1e-15 55.8 0.0 1.7e-12 47.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA36895.1 - 2.6e-08 33.5 0.0 2.3e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA36895.1 - 6.7e-08 32.1 0.0 5e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPA36895.1 - 1.1e-07 31.9 0.1 3.2e-06 27.3 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPA36895.1 - 0.0025 17.8 1.2 20 5.2 0.0 4.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KPA36895.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KPA36895.1 - 0.11 12.6 0.0 17 5.5 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KPA36895.1 - 0.12 11.1 0.2 0.41 9.3 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KPA36895.1 - 0.16 11.5 1.8 0.62 9.6 0.0 2.6 3 1 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA36895.1 - 0.18 12.4 0.1 10 6.7 0.1 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 KPA36898.1 - 4.8e-121 395.6 62.9 9.4e-17 61.4 1.2 9.3 1 1 11 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA36898.1 - 1.1e-81 268.2 33.5 4.9e-10 39.7 0.2 12.5 6 2 8 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.30 KPA36898.1 - 1.3e-58 193.0 51.7 1.5e-06 28.4 0.1 17.1 17 0 0 17 17 17 14 Ankyrin repeat Ank_3 PF13606.6 KPA36898.1 - 6.7e-55 176.6 26.1 7.6e-06 25.9 0.0 17.6 18 0 0 18 18 18 15 Ankyrin repeat Ank_5 PF13857.6 KPA36898.1 - 3e-54 180.3 20.9 7e-06 26.2 0.1 13.1 6 3 8 14 14 14 12 Ankyrin repeats (many copies) MreC PF04085.14 KPA36898.1 - 0.082 12.8 0.1 16 5.4 0.0 4.0 2 2 1 3 3 3 0 rod shape-determining protein MreC LAS2 PF15792.5 KPA36898.1 - 0.14 12.7 0.0 4 8.0 0.0 3.2 2 1 1 3 3 3 0 Lung adenoma susceptibility protein 2 PTS_IIA PF02255.16 KPA36898.1 - 0.49 10.5 5.7 1.1 9.3 1.1 3.3 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit Sugar_tr PF00083.24 KPA36899.1 - 6e-74 249.5 15.3 1.3e-73 248.5 15.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36899.1 - 1.6e-15 56.9 35.3 1.4e-12 47.3 10.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily NARG2_C PF10505.9 KPA36899.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus Rick_17kDa_Anti PF05433.15 KPA36899.1 - 0.072 13.0 0.5 0.072 13.0 0.5 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain FOXP-CC PF16159.5 KPA36901.1 - 0.058 14.0 0.5 6.6 7.4 0.0 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain Zn_Tnp_IS1 PF03811.13 KPA36901.1 - 5.6 6.8 6.1 19 5.1 6.0 2.0 1 1 0 1 1 1 0 InsA N-terminal domain WSC PF01822.19 KPA36903.1 - 6.9e-07 29.4 0.2 6.9e-07 29.4 0.2 3.0 2 0 0 2 2 2 1 WSC domain MFS_1 PF07690.16 KPA36904.1 - 2.2e-26 92.6 30.0 2.2e-26 92.6 30.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TauD PF02668.16 KPA36905.1 - 6.4e-52 177.0 0.2 7.3e-52 176.8 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TNT PF14021.6 KPA36906.1 - 4.3e-32 110.5 0.1 8.5e-32 109.6 0.0 1.5 2 0 0 2 2 2 1 Tuberculosis necrotizing toxin Condensation PF00668.20 KPA36907.1 - 6.5e-75 252.5 0.0 9.1e-43 146.6 0.0 3.9 5 0 0 5 5 5 2 Condensation domain AMP-binding PF00501.28 KPA36907.1 - 3.2e-74 250.0 0.0 1e-69 235.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KPA36907.1 - 1.4e-23 83.0 0.0 1.2e-11 44.8 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site ECH_1 PF00378.20 KPA36908.1 - 9.5e-47 159.4 0.0 1.7e-46 158.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA36908.1 - 1.2e-30 107.2 0.2 1.2e-26 94.0 0.1 2.5 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Lyase_1 PF00206.20 KPA36910.1 - 3.6e-22 79.1 0.0 5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KPA36910.1 - 8.6e-16 58.3 0.0 3.2e-15 56.4 0.0 2.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ADH_zinc_N PF00107.26 KPA36911.1 - 1e-06 28.8 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FlaG PF03646.15 KPA36911.1 - 0.039 14.1 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 FlaG protein Acetyltransf_2 PF00797.17 KPA36912.1 - 7.5e-37 127.4 0.1 4.1e-34 118.4 0.0 2.1 2 0 0 2 2 2 2 N-acetyltransferase GFO_IDH_MocA PF01408.22 KPA36915.1 - 0.013 16.4 0.0 0.013 16.3 0.0 1.1 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF953 PF06110.11 KPA36916.1 - 1.1e-14 54.1 0.0 1.2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 KPA36916.1 - 0.018 15.0 0.1 0.052 13.6 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 KPA36916.1 - 0.025 14.9 0.0 1.1 9.7 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KPA36916.1 - 0.034 13.9 0.1 0.039 13.7 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.21 KPA36916.1 - 0.035 14.0 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family GFO_IDH_MocA PF01408.22 KPA36917.1 - 1.3e-26 93.8 0.2 2.2e-26 93.0 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPA36917.1 - 3e-13 49.8 0.0 5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Shikimate_DH PF01488.20 KPA36917.1 - 0.034 14.2 0.0 0.088 12.9 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KPA36917.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3455 PF11937.8 KPA36918.1 - 4.5e-12 46.6 0.0 6.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) PARP PF00644.20 KPA36919.1 - 4.5e-23 81.9 0.0 7.9e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain BRCT PF00533.26 KPA36919.1 - 6.4e-07 29.7 0.1 1.3e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KPA36919.1 - 0.0013 19.1 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PI-PLC-X PF00388.19 KPA36919.1 - 0.039 13.5 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DASH_Dad1 PF08649.10 KPA36920.1 - 0.053 13.7 0.3 0.27 11.4 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad1 RPW8 PF05659.11 KPA36920.1 - 0.4 10.4 3.1 1.8 8.2 0.1 2.5 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF948 PF06103.11 KPA36920.1 - 0.81 10.0 5.9 1.5 9.1 0.8 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KPA36920.1 - 1.7 9.1 6.3 26 5.3 6.3 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Terpene_synth_C PF03936.16 KPA36921.1 - 0.0092 15.4 0.1 1.4 8.2 0.0 2.1 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain GST_C PF00043.25 KPA36923.1 - 0.03 14.5 0.2 0.04 14.1 0.2 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Rep_4 PF05797.11 KPA36923.1 - 0.038 13.1 0.9 0.04 13.0 0.9 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) eIF3_subunit PF08597.10 KPA36923.1 - 0.074 13.0 5.7 0.082 12.8 5.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Sugar_tr PF00083.24 KPA36925.1 - 1.1e-106 357.5 20.3 1.3e-106 357.2 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA36925.1 - 1.8e-31 109.4 29.3 5.8e-29 101.1 13.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SGL PF08450.12 KPA36926.1 - 6.4e-29 101.3 0.0 1.1e-28 100.5 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KPA36926.1 - 0.00029 21.0 0.0 0.0008 19.6 0.0 1.7 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.16 KPA36926.1 - 0.0009 19.3 0.0 0.0033 17.5 0.0 1.9 1 1 0 1 1 1 1 Strictosidine synthase NHL PF01436.21 KPA36926.1 - 0.12 12.5 0.3 15 5.8 0.0 3.0 2 0 0 2 2 2 0 NHL repeat zf-PHD-like PF15446.6 KPA36927.1 - 0.0041 16.8 0.1 0.008 15.8 0.1 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain F-box PF00646.33 KPA36929.1 - 0.0075 16.1 0.4 0.017 15.0 0.4 1.6 1 0 0 1 1 1 1 F-box domain Ank_4 PF13637.6 KPA36932.1 - 6.5e-12 45.7 2.3 0.00019 21.9 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA36932.1 - 4e-11 42.9 1.7 0.0043 17.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA36932.1 - 1.7e-08 34.9 0.0 0.00013 22.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA36932.1 - 9.3e-07 28.7 1.1 0.11 13.1 0.0 4.4 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KPA36932.1 - 0.064 13.7 4.3 14 6.3 0.6 4.3 5 1 0 5 5 5 0 Ankyrin repeat Abhydrolase_2 PF02230.16 KPA36934.1 - 2e-28 99.7 0.0 5.5e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KPA36934.1 - 7.2e-05 22.4 0.0 0.00023 20.7 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KPA36934.1 - 0.01 15.1 0.0 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KPA36934.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA36934.1 - 0.014 16.0 0.2 0.047 14.3 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA36934.1 - 0.071 12.7 0.0 0.21 11.2 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 KPA36934.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DLH PF01738.18 KPA36934.1 - 0.13 11.8 0.1 0.33 10.5 0.1 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family DASH_Dad2 PF08654.10 KPA36935.1 - 0.037 14.4 0.2 0.055 13.9 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 Aldedh PF00171.22 KPA36936.1 - 6e-154 512.9 0.0 7.1e-154 512.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KPA36936.1 - 0.0073 15.4 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) RuvC_1 PF18516.1 KPA36936.1 - 0.085 12.0 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 RuvC nuclease domain Abhydrolase_3 PF07859.13 KPA36937.1 - 1.8e-47 161.9 0.0 2.4e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPA36937.1 - 1.2e-06 27.7 0.1 8.3e-06 24.9 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KPA36937.1 - 0.0014 18.1 0.0 0.061 12.8 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KPA36937.1 - 0.21 10.2 0.0 0.34 9.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Catalase PF00199.19 KPA36938.1 - 1.5e-21 77.0 0.1 7.1e-21 74.7 0.1 1.9 1 1 0 1 1 1 1 Catalase TFIIF_alpha PF05793.12 KPA36939.1 - 0.005 15.5 5.0 0.0065 15.1 5.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sporozoite_P67 PF05642.11 KPA36939.1 - 0.2 9.7 10.1 0.23 9.5 10.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4366 PF14283.6 KPA36939.1 - 0.44 10.6 5.2 0.16 12.0 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Nop14 PF04147.12 KPA36939.1 - 0.48 8.6 6.3 0.56 8.4 6.3 1.0 1 0 0 1 1 1 0 Nop14-like family Fungal_lectin PF07938.12 KPA36940.1 - 1.3e-05 24.7 7.3 0.00014 21.4 1.7 2.7 1 1 0 2 2 2 2 Fungal fucose-specific lectin SKG6 PF08693.10 KPA36940.1 - 0.0026 17.1 0.3 0.0072 15.7 0.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KPA36940.1 - 0.0067 16.2 0.1 0.06 13.1 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF4448) Podoplanin PF05808.11 KPA36940.1 - 0.0072 16.4 0.7 0.022 14.8 0.0 2.1 3 0 0 3 3 3 1 Podoplanin VSP PF03302.13 KPA36940.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Gram_pos_anchor PF00746.21 KPA36940.1 - 0.049 13.6 0.8 0.097 12.6 0.8 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif cNMP_binding PF00027.29 KPA36941.1 - 2.7e-25 88.3 0.0 2.8e-13 49.8 0.0 2.9 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Patatin PF01734.22 KPA36941.1 - 5.2e-25 88.8 3.0 2.5e-23 83.4 3.0 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase SMP PF04927.12 KPA36943.1 - 2.5e-11 43.8 20.3 2.7e-07 31.0 8.8 2.1 1 1 1 2 2 2 2 Seed maturation protein Ifi-6-16 PF06140.13 KPA36943.1 - 0.00041 20.2 3.2 0.13 12.2 0.1 2.1 2 0 0 2 2 2 2 Interferon-induced 6-16 family adh_short PF00106.25 KPA36944.1 - 1.3e-25 90.0 0.0 2.1e-22 79.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA36944.1 - 1e-16 61.3 0.0 2.9e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA36944.1 - 3.7e-07 30.2 0.1 6.5e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA36944.1 - 0.0051 16.3 0.1 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 KPA36944.1 - 0.0071 15.6 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 KPA36944.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 KPA36944.1 - 0.045 13.1 0.1 0.082 12.3 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KPA36944.1 - 0.088 12.7 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_18 PF00704.28 KPA36945.1 - 5.4e-38 131.5 2.0 8.2e-38 130.9 2.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KPA36945.1 - 7.1e-09 35.6 0.2 0.001 19.1 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KPA36945.1 - 8.2e-08 32.6 9.4 8.2e-08 32.6 9.4 4.1 4 0 0 4 4 4 1 Chitin recognition protein 2OG-FeII_Oxy_2 PF13532.6 KPA36946.1 - 1.2e-15 58.3 0.0 1.8e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KPA36947.1 - 5.2e-19 68.4 32.2 2.4e-14 53.0 25.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA36947.1 - 1.5e-07 30.6 15.7 0.00043 19.2 1.7 2.1 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 KPA36947.1 - 0.066 11.8 30.7 0.72 8.3 15.2 3.6 2 2 1 3 3 3 0 MFS/sugar transport protein Choline_kinase PF01633.20 KPA36948.1 - 1.7e-40 138.9 0.0 2.6e-39 135.0 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KPA36948.1 - 5.9e-09 36.2 0.1 2.9e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KPA36948.1 - 0.003 16.9 0.0 0.0066 15.8 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase FNIP_N PF14636.6 KPA36949.1 - 8.4 7.3 11.9 0.92 10.5 1.2 2.5 1 1 1 2 2 2 0 Folliculin-interacting protein N-terminus RhoGAP PF00620.27 KPA36950.1 - 4.1e-43 146.8 0.1 8e-43 145.9 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KPA36950.1 - 2.4e-12 47.3 0.0 6.4e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 PH domain GOLGA2L5 PF15070.6 KPA36950.1 - 0.13 10.9 0.2 0.19 10.3 0.2 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 NolB PF17398.2 KPA36950.1 - 0.46 10.9 3.6 0.39 11.1 0.3 2.4 2 0 0 2 2 2 0 Nodulation protein NolB Dimer_Tnp_hAT PF05699.14 KPA36951.1 - 1.7e-17 63.0 0.1 3.6e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PRTP PF01366.18 KPA36951.1 - 0.11 10.5 0.0 0.17 9.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Transferase PF02458.15 KPA36952.1 - 6.4e-14 51.4 0.0 2.1e-13 49.7 0.0 1.7 1 1 0 1 1 1 1 Transferase family Aldo_ket_red PF00248.21 KPA36953.1 - 4.6e-35 121.2 0.0 6.9e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.8 KPA36953.1 - 9.7e-13 48.2 0.0 2.1e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.25 KPA36954.1 - 2.1e-19 69.8 0.0 2.3e-18 66.4 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA36954.1 - 2.9e-13 49.9 0.0 1.5e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA36954.1 - 0.00075 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KPA36954.1 - 0.033 14.0 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 KPA36954.1 - 0.1 12.0 0.1 0.6 9.5 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF218 PF02698.17 KPA36956.1 - 0.00096 19.2 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 DUF218 domain HNH_2 PF13391.6 KPA36958.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease Fungal_trans_2 PF11951.8 KPA36960.1 - 8.6e-22 77.5 2.2 1e-09 37.7 0.0 2.7 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA36960.1 - 3.1e-05 24.0 9.5 5.6e-05 23.2 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 KPA36961.1 - 5.9e-17 62.4 0.0 1.4e-16 61.1 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) KAP_NTPase PF07693.14 KPA36962.1 - 0.019 14.2 0.0 1.3 8.2 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain NACHT PF05729.12 KPA36962.1 - 0.024 14.6 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Carb_kinase PF01256.17 KPA36963.1 - 2.6e-54 184.3 0.1 4.6e-54 183.5 0.1 1.4 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KPA36963.1 - 0.00082 18.8 0.0 0.0037 16.7 0.0 2.0 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.15 KPA36963.1 - 0.0049 16.3 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family MFS_1 PF07690.16 KPA36965.1 - 4.6e-29 101.5 43.5 2.5e-20 72.7 16.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily UL45 PF05473.12 KPA36966.1 - 0.00034 20.3 1.0 0.00037 20.2 1.0 1.1 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like ATP13 PF12921.7 KPA36967.1 - 0.031 14.1 0.6 1.4 8.8 0.1 2.1 1 1 1 2 2 2 0 Mitochondrial ATPase expression TNT PF14021.6 KPA36969.1 - 3.1e-32 111.0 0.1 6.6e-32 109.9 0.0 1.5 2 0 0 2 2 2 1 Tuberculosis necrotizing toxin Peptidase_M14 PF00246.24 KPA36970.1 - 4.9e-65 220.2 0.0 5.5e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase DLH PF01738.18 KPA36971.1 - 3.9e-22 78.9 0.3 4.8e-21 75.3 0.3 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KPA36971.1 - 0.006 15.9 0.0 0.087 12.1 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPA36971.1 - 0.02 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Cellulase PF00150.18 KPA36972.1 - 3.6e-19 69.3 6.4 4.8e-19 68.8 6.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ndufs5 PF10200.9 KPA36972.1 - 0.08 13.2 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa APH PF01636.23 KPA36973.1 - 0.0073 16.2 0.0 0.0091 15.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_16 PF00722.21 KPA36974.1 - 1.9e-16 60.0 0.4 2.7e-16 59.5 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KPA36974.1 - 5.6e-07 28.3 2.9 0.0046 15.4 0.7 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Asparaginase_2 PF01112.18 KPA36975.1 - 2.8e-45 154.7 1.7 1.6e-28 99.6 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Actin PF00022.19 KPA36976.1 - 3.8e-87 292.6 0.0 2e-52 178.2 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KPA36976.1 - 0.058 12.2 0.0 3 6.6 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein ADH_N PF08240.12 KPA36977.1 - 1.6e-29 102.0 0.3 2.8e-29 101.2 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA36977.1 - 1.1e-22 80.4 0.3 1.8e-22 79.7 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA36977.1 - 8.6e-06 26.8 0.1 1.5e-05 26.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HMA PF00403.26 KPA36978.1 - 3e-14 53.2 1.0 3.1e-14 53.1 0.1 1.5 2 0 0 2 2 2 1 Heavy-metal-associated domain Abhydrolase_1 PF00561.20 KPA36979.1 - 3.2e-07 30.3 0.0 5.2e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA36979.1 - 5.6e-05 23.8 0.0 6.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.18 KPA36980.1 - 5.3e-08 32.2 2.3 6.6e-08 31.9 0.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA36980.1 - 1e-06 28.7 8.7 2e-06 27.8 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Raptor_N PF14538.6 KPA36980.1 - 0.095 12.6 0.1 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain VWA_3 PF13768.6 KPA36982.1 - 6.2e-20 71.7 0.0 9.7e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KPA36982.1 - 1.3e-09 38.5 0.0 2.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KPA36982.1 - 3.4e-08 34.1 0.0 6.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 KPA36983.1 - 1.3e-30 105.9 0.2 1.8e-30 105.4 0.2 1.2 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.6 KPA36983.1 - 8.9e-08 31.9 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain NmrA PF05368.13 KPA36984.1 - 3.2e-27 95.6 0.2 5.6e-27 94.8 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA36984.1 - 4.1e-16 59.4 0.0 9e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Peptidase_S8 PF00082.22 KPA36984.1 - 1e-09 38.1 5.8 3.6e-09 36.3 5.8 1.9 1 1 0 1 1 1 1 Subtilase family Epimerase PF01370.21 KPA36984.1 - 0.0017 17.9 0.3 0.015 14.8 0.0 2.5 3 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KPA36984.1 - 0.0087 16.1 0.3 0.019 15.0 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KPA36984.1 - 0.011 15.9 0.1 0.046 13.9 0.1 2.2 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Pectate_lyase_3 PF12708.7 KPA36985.1 - 2.5e-41 141.9 2.7 7.5e-31 107.6 0.3 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KPA36985.1 - 0.12 12.1 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase TMEM154 PF15102.6 KPA36986.1 - 0.00011 22.1 0.3 0.00011 22.1 0.3 3.1 1 1 2 3 3 3 1 TMEM154 protein family SPX PF03105.19 KPA36986.1 - 0.0052 16.8 1.1 0.0053 16.7 1.1 1.1 1 0 0 1 1 1 1 SPX domain EphA2_TM PF14575.6 KPA36986.1 - 0.17 12.8 0.4 0.44 11.5 0.4 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAPG_hydrolase PF18089.1 KPA36987.1 - 8.2e-50 169.4 3.9 2.9e-43 148.0 0.9 2.1 1 1 1 2 2 2 2 DAPG hydrolase PhiG domain Aa_trans PF01490.18 KPA36988.1 - 2.9e-47 161.3 33.2 3.3e-47 161.1 33.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 KPA36988.1 - 0.19 11.6 2.4 0.6 10.0 0.2 3.1 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase HhH-GPD PF00730.25 KPA36989.1 - 1.6e-08 34.9 0.0 2.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HEAT PF02985.22 KPA36990.1 - 0.018 15.2 0.1 0.038 14.2 0.1 1.5 1 0 0 1 1 1 0 HEAT repeat APH PF01636.23 KPA36991.1 - 2.9e-21 76.5 0.5 4e-21 76.0 0.5 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPA36991.1 - 4.3e-05 23.2 0.0 6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KPA36991.1 - 5.2e-05 22.9 0.0 0.0052 16.4 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Kdo PF06293.14 KPA36991.1 - 0.067 12.5 0.0 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3987 PF13148.6 KPA36992.1 - 0.05 12.6 0.1 0.088 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Smr PF01713.21 KPA36992.1 - 0.16 12.3 0.1 1.3 9.5 0.0 2.4 3 0 0 3 3 3 0 Smr domain Pkinase PF00069.25 KPA36993.1 - 1.5e-05 24.5 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KPA36993.1 - 6.8e-05 22.9 0.4 0.00038 20.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPA36993.1 - 0.097 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase AA_permease_C PF13906.6 KPA36994.1 - 0.24 11.5 1.3 0.4 10.8 1.3 1.3 1 0 0 1 1 1 0 C-terminus of AA_permease OrsD PF12013.8 KPA36996.1 - 5.9e-16 58.9 0.7 9.1e-16 58.3 0.7 1.3 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Actin_micro PF17003.5 KPA36996.1 - 0.018 14.3 0.1 0.19 10.9 0.0 2.0 1 1 1 2 2 2 0 Putative actin-like family Rpr2 PF04032.16 KPA36996.1 - 0.022 15.0 0.1 0.073 13.4 0.1 1.9 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_2 PF12756.7 KPA36996.1 - 0.15 12.4 0.3 0.74 10.2 0.3 1.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KPA36997.1 - 0.031 14.7 0.6 0.031 14.7 0.6 3.9 5 1 0 5 5 5 0 Zinc-finger double domain zf-C2H2 PF00096.26 KPA36997.1 - 0.038 14.4 0.8 0.038 14.4 0.8 4.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA36997.1 - 0.42 11.6 24.2 0.17 12.8 1.4 5.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-CHCC PF10276.9 KPA36997.1 - 0.55 10.3 5.4 13 6.0 1.6 2.4 2 0 0 2 2 2 0 Zinc-finger domain Zn_ribbon_recom PF13408.6 KPA36997.1 - 1 9.9 10.5 3.2 8.3 1.8 3.1 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain DSPc PF00782.20 KPA36998.1 - 1.3e-12 47.7 0.0 5.4e-07 29.5 0.0 3.2 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain TraI_2_C PF07515.11 KPA36998.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term Init_tRNA_PT PF04179.12 KPA36998.1 - 0.14 12.5 0.0 0.41 11.0 0.0 1.8 1 1 0 1 1 1 0 Rit1 DUSP-like domain EPF PF17181.4 KPA36998.1 - 7.8 6.6 6.2 6.3 6.9 0.2 2.9 3 0 0 3 3 3 0 Epidermal patterning factor proteins Fungal_trans_2 PF11951.8 KPA36999.1 - 0.00011 21.2 0.3 0.00088 18.2 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3618 PF12277.8 KPA36999.1 - 0.0062 16.8 0.5 0.0062 16.8 0.5 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3618) adh_short PF00106.25 KPA37000.1 - 1.3e-22 80.3 0.0 9e-19 67.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37000.1 - 2.4e-10 40.3 0.0 2.3e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA37000.1 - 0.00072 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 KR domain zf-CCHC PF00098.23 KPA37002.1 - 0.00037 20.4 10.1 0.0099 15.9 0.6 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 KPA37002.1 - 0.15 11.8 0.7 0.15 11.8 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 KPA37002.1 - 8 6.3 13.5 0.33 10.7 5.2 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Chromo PF00385.24 KPA37003.1 - 0.028 14.3 5.7 3.2 7.7 0.0 2.7 2 1 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.25 KPA37004.1 - 8.3e-08 31.9 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KPA37004.1 - 0.00069 19.0 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPA37004.1 - 0.00097 19.1 0.8 0.006 16.5 0.4 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KPA37004.1 - 0.024 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL YcaO_C PF18381.1 KPA37004.1 - 0.091 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain SUI1 PF01253.22 KPA37005.1 - 4.2e-28 97.7 3.7 5.4e-28 97.3 3.7 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 EOS1 PF12326.8 KPA37006.1 - 2.7e-15 56.7 1.6 2.7e-15 56.7 1.6 2.1 1 1 1 2 2 2 1 N-glycosylation protein Spc7_C2 PF15577.6 KPA37006.1 - 2.8 8.1 5.0 5.8 7.1 0.0 2.9 3 0 0 3 3 3 0 Spc7_C2 RRM_1 PF00076.22 KPA37008.1 - 4.2e-10 39.3 0.1 1.3e-09 37.7 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 KPA37009.1 - 2.1e-32 112.4 34.2 4.2e-26 91.7 18.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA37009.1 - 2.9e-12 46.2 0.5 2.9e-12 46.2 0.5 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KPA37009.1 - 0.0026 16.2 10.2 0.036 12.5 3.5 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Transgly_assoc PF04226.13 KPA37009.1 - 2.5 8.4 16.0 2.6 8.4 0.2 4.3 3 1 0 3 3 3 0 Transglycosylase associated protein NTP_transf_9 PF04248.12 KPA37010.1 - 1.5e-39 133.8 0.1 8.8e-32 108.9 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Peptidase_S8 PF00082.22 KPA37011.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Subtilase family Ank_2 PF12796.7 KPA37012.1 - 5.3e-37 126.3 2.8 1.3e-15 57.7 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA37012.1 - 3.4e-28 97.4 3.0 7.1e-10 38.9 0.0 5.4 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPA37012.1 - 1.1e-27 96.0 0.3 7.3e-06 26.4 0.1 6.1 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KPA37012.1 - 1.8e-27 94.6 0.6 2.5e-05 24.5 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KPA37012.1 - 4e-26 88.2 0.4 7.1e-05 22.9 0.1 6.2 6 0 0 6 6 6 5 Ankyrin repeat Shigella_OspC PF06128.11 KPA37012.1 - 0.048 13.4 0.7 15 5.2 0.0 2.9 1 1 3 4 4 4 0 Shigella flexneri OspC protein MFS_1 PF07690.16 KPA37013.1 - 3.6e-27 95.2 25.5 3.6e-27 95.2 25.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA37013.1 - 1.8e-08 33.7 2.3 1.8e-08 33.7 2.3 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter Aldedh PF00171.22 KPA37014.1 - 1.2e-115 386.6 0.0 1.6e-115 386.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cupin_2 PF07883.11 KPA37015.1 - 1.3e-23 82.5 0.7 4.8e-14 51.8 0.2 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KPA37015.1 - 0.00018 21.1 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KPA37015.1 - 0.018 14.9 1.7 3.7 7.4 0.1 2.7 2 1 1 3 3 3 0 AraC-like ligand binding domain CENP-C_C PF11699.8 KPA37015.1 - 0.046 13.9 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 Mif2/CENP-C like COesterase PF00135.28 KPA37015.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family FAD_binding_3 PF01494.19 KPA37016.1 - 5.1e-22 78.6 0.0 7.2e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA37016.1 - 7.6e-11 42.2 4.7 0.00017 21.3 5.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA37016.1 - 2.1e-08 33.8 0.9 0.00079 18.7 1.6 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA37016.1 - 2.3e-08 34.1 2.1 4.4e-08 33.2 1.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KPA37016.1 - 6.7e-07 28.5 0.7 0.024 13.5 0.2 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.27 KPA37016.1 - 6.1e-06 26.7 0.1 0.0051 17.3 0.3 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA37016.1 - 1e-05 24.5 1.3 0.0079 14.9 1.5 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KPA37016.1 - 1.9e-05 24.0 4.0 3.3e-05 23.1 4.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KPA37016.1 - 3.7e-05 23.1 0.5 0.0089 15.3 1.3 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KPA37016.1 - 0.0016 17.6 3.0 0.32 10.0 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KPA37016.1 - 0.0024 17.9 0.0 0.0072 16.3 0.0 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KPA37016.1 - 0.0069 15.8 7.0 0.014 14.8 7.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KPA37016.1 - 0.0087 15.2 1.5 0.041 13.0 2.5 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KPA37016.1 - 0.0095 15.3 3.6 0.16 11.2 2.2 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Glyco_trans_4_4 PF13579.6 KPA37016.1 - 0.021 15.3 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Rossmann-like PF10727.9 KPA37016.1 - 0.03 14.2 5.5 0.076 12.9 1.1 2.4 2 0 0 2 2 2 0 Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 KPA37016.1 - 0.031 13.8 0.2 0.056 13.0 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KPA37016.1 - 0.036 13.3 1.7 0.13 11.5 2.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KPA37016.1 - 0.051 12.6 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase ApbA PF02558.16 KPA37016.1 - 0.09 12.4 1.0 0.16 11.6 1.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RHH_4 PF13467.6 KPA37016.1 - 0.13 12.2 0.1 0.33 10.9 0.1 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix domain MCRA PF06100.11 KPA37016.1 - 0.2 10.4 0.5 0.35 9.6 0.5 1.3 1 0 0 1 1 1 0 MCRA family 3HCDH_N PF02737.18 KPA37016.1 - 0.58 10.0 2.4 1.1 9.1 2.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAA_hydrolase PF01557.18 KPA37017.1 - 3.1e-58 197.0 0.0 3.9e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 KPA37018.1 - 4.1e-25 88.3 1.4 9.8e-25 87.1 1.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37018.1 - 1e-08 35.1 6.2 1e-08 35.1 6.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 KPA37018.1 - 0.099 11.7 2.0 0.15 11.1 2.0 1.2 1 0 0 1 1 1 0 Clusterin NACHT_N PF17100.5 KPA37019.1 - 2.2e-86 289.3 0.5 2.6e-86 289.0 0.5 1.0 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase tRNA-synt_2_TM PF16995.5 KPA37019.1 - 0.11 12.1 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase DUF5082 PF16888.5 KPA37020.1 - 0.0037 17.5 1.0 0.0062 16.8 0.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) Topoisom_I_N PF02919.15 KPA37020.1 - 0.13 11.7 4.5 0.48 9.9 4.5 1.8 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Allexi_40kDa PF05549.11 KPA37020.1 - 0.54 9.7 4.1 1.3 8.4 2.7 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein Zn_clus PF00172.18 KPA37021.1 - 5.3e-09 36.1 11.6 1e-08 35.1 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABM PF03992.16 KPA37021.1 - 2e-08 34.3 2.1 3.7e-08 33.4 0.2 2.3 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase F-box-like PF12937.7 KPA37022.1 - 0.33 10.9 0.0 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 F-box-like ArAE_2_N PF10337.9 KPA37023.1 - 1.7e-104 350.5 0.0 4.5e-103 345.8 0.0 2.1 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KPA37023.1 - 4.4e-54 183.7 0.0 7.4e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KPA37023.1 - 3.6e-09 36.8 14.9 3.6e-09 36.8 14.9 3.6 3 2 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 KPA37023.1 - 0.61 8.9 6.2 1.1 8.0 6.2 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter AATase PF07247.12 KPA37026.1 - 3.7e-18 65.4 0.0 8.4e-18 64.2 0.0 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Metallophos PF00149.28 KPA37028.1 - 3.2e-18 67.0 0.1 6.6e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPA37028.1 - 0.00011 22.5 0.0 0.00057 20.1 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SAP PF02037.27 KPA37029.1 - 1e-13 50.7 0.1 2.2e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 KPA37029.1 - 2.2e-06 27.3 2.6 2.2e-06 27.3 2.6 2.1 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain HeH PF12949.7 KPA37029.1 - 0.026 14.2 0.4 0.064 13.0 0.4 1.7 1 1 0 1 1 1 0 HeH/LEM domain FANC_SAP PF18081.1 KPA37029.1 - 0.059 13.5 0.3 0.18 12.0 0.3 1.9 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain IDO PF01231.18 KPA37031.1 - 5.5e-33 114.4 0.0 8.5e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Aa_trans PF01490.18 KPA37032.1 - 3.1e-57 194.1 35.8 3.5e-57 194.0 35.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Gemini_mov PF01708.16 KPA37032.1 - 5.2 6.9 5.0 37 4.2 0.0 3.6 3 1 0 3 3 3 0 Geminivirus putative movement protein Arrestin_N PF00339.29 KPA37033.1 - 9.9e-06 25.7 0.1 0.00028 21.0 0.0 3.1 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 KPA37033.1 - 1.6e-05 24.5 0.2 3e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 Bul1 C terminus Bul1_N PF04425.12 KPA37033.1 - 2.2e-05 23.4 0.1 0.00059 18.7 0.0 2.7 1 1 1 3 3 3 1 Bul1 N terminus NOB1_Zn_bind PF08772.11 KPA37034.1 - 1.5e-32 111.5 2.5 2.5e-32 110.8 2.5 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KPA37034.1 - 1.2e-30 105.8 0.7 3e-30 104.6 0.0 2.1 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 KPA37034.1 - 0.013 15.2 0.4 0.013 15.2 0.4 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Rhodanese_C PF12368.8 KPA37034.1 - 0.017 15.5 0.5 0.031 14.7 0.5 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal PIN_5 PF08745.11 KPA37034.1 - 0.024 14.1 0.1 4.2 6.7 0.0 2.8 2 1 1 3 3 3 0 PINc domain ribonuclease DUF2616 PF11077.8 KPA37034.1 - 0.067 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) zinc-ribbons_6 PF07191.12 KPA37034.1 - 0.084 12.9 0.8 0.15 12.0 0.8 1.3 1 0 0 1 1 1 0 zinc-ribbons E6 PF00518.17 KPA37034.1 - 0.1 13.1 0.2 0.18 12.2 0.2 1.4 1 0 0 1 1 1 0 Early Protein (E6) SAM_decarbox PF01536.16 KPA37035.1 - 3e-135 450.8 0.0 3.7e-135 450.5 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Amidohydro_1 PF01979.20 KPA37036.1 - 3.1e-21 76.1 0.0 5.9e-21 75.2 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPA37036.1 - 4.7e-09 36.2 2.4 4.2e-05 23.2 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Acetyltransf_2 PF00797.17 KPA37039.1 - 7.7e-06 25.9 0.2 0.026 14.3 0.1 3.0 2 1 1 3 3 3 3 N-acetyltransferase DUF1349 PF07081.11 KPA37040.1 - 1e-10 41.6 0.0 2.2e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) Ank_2 PF12796.7 KPA37042.1 - 2.9e-09 37.4 0.1 2.6e-08 34.4 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA37042.1 - 2.5e-07 30.4 0.1 0.077 13.6 0.2 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KPA37042.1 - 0.00048 20.6 0.2 0.013 16.1 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KPA37042.1 - 0.00069 19.9 0.5 3.2 8.4 0.3 3.7 3 1 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KPA37042.1 - 0.029 14.7 0.8 0.62 10.4 0.7 2.9 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Peptidase_M11 PF05548.11 KPA37042.1 - 0.087 12.0 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Gametolysin peptidase M11 Methyltransf_23 PF13489.6 KPA37043.1 - 1.7e-09 37.7 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF2716 PF10898.8 KPA37045.1 - 0.014 15.7 0.1 0.03 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) DREV PF05219.12 KPA37045.1 - 0.031 13.4 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Spore_YhcN_YlaJ PF09580.10 KPA37045.1 - 1.6 8.8 5.1 1 9.5 1.4 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ADH_zinc_N_2 PF13602.6 KPA37046.1 - 4.2e-25 89.3 0.0 7e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KPA37046.1 - 1.1e-15 57.7 0.0 2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA37046.1 - 0.00024 20.9 0.0 0.00092 19.1 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.6 KPA37046.1 - 0.033 14.9 0.0 0.088 13.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Glu_dehyd_C PF16912.5 KPA37046.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Amidohydro_3 PF07969.11 KPA37048.1 - 1.1e-72 246.0 0.3 1.3e-72 245.9 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KPA37048.1 - 3.4e-16 59.5 0.0 3.3e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family AcetDehyd-dimer PF09290.11 KPA37048.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Amidase PF01425.21 KPA37049.1 - 4.8e-98 329.1 0.0 1.5e-54 185.7 0.0 2.1 1 1 1 2 2 2 2 Amidase KR PF08659.10 KPA37050.1 - 5.6e-52 176.3 0.2 1.6e-51 174.8 0.2 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KPA37050.1 - 5.5e-42 144.0 0.0 9.5e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KPA37050.1 - 1.5e-40 139.4 0.5 8.5e-40 136.9 0.5 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KPA37050.1 - 3.2e-29 101.3 1.2 7.9e-29 100.1 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KPA37050.1 - 1.6e-26 93.5 0.2 7e-20 71.8 0.6 2.4 1 1 1 2 2 2 2 Acyl transferase domain Methyltransf_12 PF08242.12 KPA37050.1 - 8.5e-21 74.6 0.0 2.3e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KPA37050.1 - 2.5e-18 66.6 0.0 8.6e-18 64.8 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KPA37050.1 - 6e-14 52.5 0.0 2.9e-13 50.4 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA37050.1 - 3.1e-12 47.0 0.0 1.3e-11 44.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KPA37050.1 - 1.2e-10 41.1 0.3 3e-09 36.6 0.0 2.4 1 1 1 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KPA37050.1 - 9.5e-10 38.5 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA37050.1 - 1.2e-09 38.2 0.0 2.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA37050.1 - 1.6e-09 37.5 0.0 3.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KPA37050.1 - 0.002 17.5 0.0 0.005 16.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain PCMT PF01135.19 KPA37050.1 - 0.003 17.3 0.0 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 KPA37050.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF2624 PF11116.8 KPA37050.1 - 0.076 13.9 0.2 0.2 12.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) PP-binding PF00550.25 KPA37050.1 - 0.085 13.2 0.1 0.28 11.6 0.1 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site SLT PF01464.20 KPA37051.1 - 2.6e-10 40.0 0.0 3.9e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain GFO_IDH_MocA PF01408.22 KPA37052.1 - 1.8e-19 70.7 0.0 3.6e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPA37052.1 - 5.6e-10 39.3 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KPA37052.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KPA37053.1 - 9.8e-21 74.8 0.0 1.6e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KPA37053.1 - 0.026 15.2 0.0 0.046 14.4 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sulfatase PF00884.23 KPA37054.1 - 2e-20 73.4 1.4 4.2e-20 72.4 1.4 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPA37054.1 - 0.00085 19.0 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KPA37054.1 - 0.0013 17.5 0.0 0.0018 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) adh_short PF00106.25 KPA37055.1 - 1.8e-12 47.2 0.0 7.2e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37055.1 - 2.1e-07 30.8 0.0 0.0077 15.8 0.0 2.4 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA37055.1 - 0.0002 21.3 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA37055.1 - 0.0061 15.7 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPA37055.1 - 0.017 14.6 0.1 0.06 12.8 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA37055.1 - 0.089 12.2 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase BAH PF01426.18 KPA37057.1 - 3.9e-09 36.4 0.1 7.9e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 BAH domain SH3_2 PF07653.17 KPA37057.1 - 0.12 12.0 0.1 0.4 10.4 0.1 1.8 2 0 0 2 2 2 0 Variant SH3 domain NYN PF01936.18 KPA37058.1 - 3.2e-30 105.5 0.0 5.2e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 KPA37058.1 - 8.7e-15 54.3 0.0 1.8e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 OST-HTH/LOTUS domain PspA_IM30 PF04012.12 KPA37059.1 - 6.8e-05 22.5 4.8 0.00011 21.9 4.8 1.2 1 0 0 1 1 1 1 PspA/IM30 family Leu_zip PF15294.6 KPA37059.1 - 7.7e-05 22.3 5.9 0.00011 21.8 5.9 1.2 1 0 0 1 1 1 1 Leucine zipper ABC_tran_CTD PF16326.5 KPA37059.1 - 0.0004 20.6 9.9 0.0004 20.6 9.9 2.5 1 1 2 3 3 3 1 ABC transporter C-terminal domain SHE3 PF17078.5 KPA37059.1 - 0.00077 19.2 5.0 0.0012 18.6 5.0 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Jnk-SapK_ap_N PF09744.9 KPA37059.1 - 0.00084 19.6 8.6 0.0014 18.9 8.6 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Rootletin PF15035.6 KPA37059.1 - 0.001 19.1 0.4 0.0017 18.4 0.4 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.21 KPA37059.1 - 0.0027 17.8 8.8 0.15 12.1 2.6 3.4 2 1 1 3 3 3 1 bZIP transcription factor EzrA PF06160.12 KPA37059.1 - 0.004 15.4 6.1 0.0058 14.9 6.1 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA GAS PF13851.6 KPA37059.1 - 0.0044 16.4 11.6 0.028 13.8 11.6 2.0 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 KPA37059.1 - 0.0053 17.0 6.5 0.012 15.8 6.5 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding HemX PF04375.14 KPA37059.1 - 0.0059 15.9 4.8 0.0091 15.3 4.8 1.3 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Tropomyosin_1 PF12718.7 KPA37059.1 - 0.0062 16.7 7.5 0.012 15.8 7.5 1.4 1 0 0 1 1 1 1 Tropomyosin like Mod_r PF07200.13 KPA37059.1 - 0.0065 16.6 9.1 0.016 15.3 8.6 1.8 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DMPK_coil PF08826.10 KPA37059.1 - 0.0069 16.5 4.2 0.054 13.6 4.7 2.3 2 0 0 2 2 1 1 DMPK coiled coil domain like BLOC1_2 PF10046.9 KPA37059.1 - 0.0073 16.6 7.5 0.024 14.9 6.6 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3552 PF12072.8 KPA37059.1 - 0.0089 15.5 6.8 0.015 14.7 6.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ATG16 PF08614.11 KPA37059.1 - 0.012 15.9 11.4 0.017 15.3 10.7 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KPA37059.1 - 0.013 15.3 9.0 0.024 14.5 8.6 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Taxilin PF09728.9 KPA37059.1 - 0.015 14.5 6.7 0.022 14.0 6.7 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein MAD PF05557.13 KPA37059.1 - 0.016 13.6 7.0 0.024 13.0 7.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein ZapB PF06005.12 KPA37059.1 - 0.019 15.4 10.5 0.019 15.4 10.5 2.5 1 1 2 3 3 3 0 Cell division protein ZapB YabA PF06156.13 KPA37059.1 - 0.02 15.5 5.5 0.046 14.4 5.5 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Sec34 PF04136.15 KPA37059.1 - 0.021 14.7 3.5 0.053 13.4 3.5 1.7 1 0 0 1 1 1 0 Sec34-like family FPP PF05911.11 KPA37059.1 - 0.026 12.7 6.0 0.037 12.2 6.0 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil TolA_bind_tri PF16331.5 KPA37059.1 - 0.027 14.5 7.3 0.17 12.0 4.3 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation Nup54 PF13874.6 KPA37059.1 - 0.034 14.2 2.9 0.068 13.3 2.9 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 CENP-K PF11802.8 KPA37059.1 - 0.035 13.7 4.8 0.051 13.1 4.8 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Fmp27_WPPW PF10359.9 KPA37059.1 - 0.043 12.7 2.5 0.06 12.2 2.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Baculo_PEP_C PF04513.12 KPA37059.1 - 0.045 13.8 0.7 0.37 10.8 0.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 KPA37059.1 - 0.046 12.3 2.4 0.07 11.7 2.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family BRE1 PF08647.11 KPA37059.1 - 0.048 13.7 6.9 0.089 12.9 6.9 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Uso1_p115_C PF04871.13 KPA37059.1 - 0.052 13.9 6.3 0.096 13.1 6.3 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HALZ PF02183.18 KPA37059.1 - 0.055 13.7 3.4 0.35 11.1 0.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Phage_GP20 PF06810.11 KPA37059.1 - 0.058 13.2 9.4 0.18 11.6 5.2 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Spc7 PF08317.11 KPA37059.1 - 0.059 12.3 10.9 0.089 11.7 10.2 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 KPA37059.1 - 0.062 13.8 15.7 0.094 13.2 14.9 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region ADIP PF11559.8 KPA37059.1 - 0.069 13.2 9.0 0.15 12.2 9.0 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.12 KPA37059.1 - 0.096 12.7 1.7 0.28 11.2 1.4 1.9 2 0 0 2 2 1 0 Laminin Domain II FapA PF03961.13 KPA37059.1 - 0.12 11.0 3.1 0.17 10.5 3.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc29 PF17082.5 KPA37059.1 - 0.12 12.2 2.8 0.39 10.5 2.4 2.0 1 1 0 1 1 1 0 Spindle Pole Component 29 UPF0242 PF06785.11 KPA37059.1 - 0.15 12.2 7.7 0.23 11.6 7.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus WXG100 PF06013.12 KPA37059.1 - 0.15 12.3 2.7 0.88 9.8 2.5 2.3 1 1 0 1 1 1 0 Proteins of 100 residues with WXG CENP-Q PF13094.6 KPA37059.1 - 0.16 12.2 5.6 0.3 11.3 5.6 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.15 KPA37059.1 - 0.16 11.8 9.5 0.57 10.0 6.6 2.6 1 1 1 2 2 2 0 Septum formation initiator CENP-H PF05837.12 KPA37059.1 - 0.19 12.2 3.1 0.44 11.0 3.1 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Atg14 PF10186.9 KPA37059.1 - 0.19 10.8 4.1 0.32 10.0 4.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 KPA37059.1 - 0.19 11.7 10.2 0.12 12.4 7.4 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 KPA37059.1 - 0.2 10.9 2.7 0.3 10.3 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin PF00804.25 KPA37059.1 - 0.21 11.2 6.0 0.39 10.3 4.4 1.9 1 1 0 2 2 2 0 Syntaxin DASH_Spc19 PF08287.11 KPA37059.1 - 0.23 11.3 7.0 0.44 10.4 6.6 1.6 1 1 0 1 1 1 0 Spc19 T3SSipB PF16535.5 KPA37059.1 - 0.25 11.8 2.9 0.49 10.9 2.9 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF3584 PF12128.8 KPA37059.1 - 0.25 8.8 9.2 0.32 8.5 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rota_NSP3 PF01665.16 KPA37059.1 - 0.26 10.4 2.8 0.69 9.0 2.2 1.8 1 1 1 2 2 2 0 Rotavirus non-structural protein NSP3 Cep57_CLD_2 PF14197.6 KPA37059.1 - 0.32 11.1 7.4 0.83 9.8 7.4 1.8 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF573 PF04504.14 KPA37059.1 - 0.32 11.7 2.8 9.7 6.9 0.6 2.8 1 1 1 2 2 2 0 Protein of unknown function, DUF573 SLATT_6 PF18169.1 KPA37059.1 - 0.36 10.4 2.1 0.67 9.5 1.6 1.6 1 1 1 2 2 1 0 SMODS and SLOG-associating 2TM effector domain 6 CENP-F_leu_zip PF10473.9 KPA37059.1 - 0.39 10.8 10.8 0.56 10.2 10.2 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.19 KPA37059.1 - 0.41 8.5 4.3 0.54 8.1 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin PF00261.20 KPA37059.1 - 0.44 9.9 14.0 0.95 8.8 12.6 1.9 1 1 1 2 2 2 0 Tropomyosin NPV_P10 PF05531.12 KPA37059.1 - 0.48 10.9 3.7 14 6.2 2.8 3.2 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein bZIP_2 PF07716.15 KPA37059.1 - 0.51 10.4 10.6 3.3 7.9 5.4 2.9 1 1 2 3 3 3 0 Basic region leucine zipper XhlA PF10779.9 KPA37059.1 - 0.52 10.6 5.5 0.89 9.8 3.3 2.5 2 1 0 2 2 1 0 Haemolysin XhlA ACP_PD PF04336.12 KPA37059.1 - 0.52 10.7 2.6 4 7.9 0.5 2.5 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase FliD_N PF02465.18 KPA37059.1 - 0.65 10.7 5.0 4.6 8.0 5.0 2.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus 5_nucleotid PF05761.14 KPA37059.1 - 0.73 8.7 3.8 1.1 8.1 3.8 1.2 1 0 0 1 1 1 0 5' nucleotidase family DUF4407 PF14362.6 KPA37059.1 - 0.87 8.9 7.0 1.5 8.1 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KPA37059.1 - 0.89 9.6 3.0 4.6 7.3 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KPA37059.1 - 0.97 9.9 4.2 3.9 7.9 0.5 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 KPA37059.1 - 1 10.1 7.2 3.3 8.5 6.7 2.0 1 1 0 1 1 1 0 Occludin homology domain TSC22 PF01166.18 KPA37059.1 - 1.1 9.6 9.0 2.7 8.4 5.5 2.7 1 1 1 2 2 2 0 TSC-22/dip/bun family Ax_dynein_light PF10211.9 KPA37059.1 - 1.2 9.1 9.6 3.6 7.5 9.7 1.8 1 1 0 1 1 1 0 Axonemal dynein light chain Prefoldin_2 PF01920.20 KPA37059.1 - 1.4 8.9 11.4 1.1 9.3 6.3 2.5 1 1 1 2 2 2 0 Prefoldin subunit Nup88 PF10168.9 KPA37059.1 - 1.5 6.5 7.2 2 6.1 7.2 1.1 1 0 0 1 1 1 0 Nuclear pore component TPR_MLP1_2 PF07926.12 KPA37059.1 - 1.8 8.6 13.1 1.2 9.2 9.1 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Csm1_N PF18504.1 KPA37059.1 - 2.3 8.6 10.6 8.2 6.9 4.7 2.6 2 1 1 3 3 2 0 Csm1 N-terminal domain Fzo_mitofusin PF04799.13 KPA37059.1 - 2.4 7.7 4.7 13 5.3 3.7 2.2 1 1 1 2 2 2 0 fzo-like conserved region DUF4795 PF16043.5 KPA37059.1 - 2.9 7.4 8.0 7.6 6.1 8.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4140 PF13600.6 KPA37059.1 - 7.6 7.1 10.5 7.8 7.0 3.6 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.14 KPA37059.1 - 7.6 6.9 15.0 16 5.8 15.0 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF16 PF01519.16 KPA37059.1 - 8.3 7.0 9.6 2.7 8.5 5.1 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 MIS13 PF08202.11 KPA37060.1 - 3.3e-38 131.7 0.0 5.6e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family SKA2 PF16740.5 KPA37060.1 - 0.16 11.8 0.7 3.3 7.5 0.1 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Fungal_trans PF04082.18 KPA37061.1 - 4.1e-15 55.5 7.0 8e-15 54.6 7.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KPA37061.1 - 6.6e-07 29.6 14.1 0.00045 20.8 1.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA37061.1 - 9.2e-07 29.0 10.9 3.1e-05 24.2 1.8 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KPA37061.1 - 4.9e-06 26.6 13.3 4.9e-06 26.6 13.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KPA37061.1 - 0.0051 17.2 1.5 0.0051 17.2 1.5 3.9 3 1 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KPA37061.1 - 0.0078 16.6 3.4 0.048 14.1 0.1 3.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KPA37061.1 - 0.019 15.2 0.8 0.053 13.8 0.8 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KPA37061.1 - 0.062 13.6 4.4 13 6.2 0.3 3.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KPA37061.1 - 1.9 8.3 6.6 12 5.8 0.7 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KPA37061.1 - 2 8.5 5.6 17 5.5 0.2 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger p450 PF00067.22 KPA37062.1 - 2.2e-60 204.7 0.0 2.9e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KPA37063.1 - 1.8e-30 105.5 0.0 2.9e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KPA37063.1 - 2.2e-07 30.7 0.0 3.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FMO-like PF00743.19 KPA37064.1 - 6.5e-20 71.1 1.2 1e-18 67.1 0.1 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPA37064.1 - 1.4e-10 41.3 0.0 3.6e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA37064.1 - 1.9e-08 33.9 0.0 3.9e-07 29.6 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA37064.1 - 6.1e-07 28.9 0.0 2.1e-05 23.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPA37064.1 - 4e-05 23.0 0.0 0.00028 20.3 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA37064.1 - 0.033 13.8 0.0 40 3.6 0.0 3.4 2 1 1 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 KPA37064.1 - 0.12 11.6 0.0 12 5.1 0.0 2.6 3 0 0 3 3 3 0 Thi4 family FAD_binding_3 PF01494.19 KPA37065.1 - 4.2e-14 52.6 0.0 5e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPA37065.1 - 8.9e-05 22.6 0.1 0.00025 21.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPA37065.1 - 0.00021 21.3 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 KPA37065.1 - 0.0086 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KPA37065.1 - 0.0089 15.6 0.1 0.016 14.8 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase DUF4944 PF16302.5 KPA37065.1 - 0.062 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) K_oxygenase PF13434.6 KPA37065.1 - 0.065 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Lactamase_B_3 PF13483.6 KPA37066.1 - 6.7e-09 35.9 0.0 6.3e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KPA37066.1 - 5e-06 26.2 0.1 7.8e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KPA37066.1 - 1.3e-05 25.3 0.2 2e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PAN_4 PF14295.6 KPA37067.1 - 0.011 15.6 0.3 0.027 14.4 0.3 1.7 1 0 0 1 1 1 0 PAN domain PAN_1 PF00024.26 KPA37067.1 - 0.014 15.3 6.5 0.045 13.7 6.5 1.9 1 0 0 1 1 1 0 PAN domain RTA1 PF04479.13 KPA37068.1 - 1.4e-72 243.7 10.9 1.8e-72 243.3 10.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF4293 PF14126.6 KPA37068.1 - 0.36 11.1 0.1 0.36 11.1 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) RseC_MucC PF04246.12 KPA37068.1 - 4.9 7.1 6.0 2.8 7.9 0.2 2.8 3 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DctQ PF04290.12 KPA37068.1 - 5.5 6.9 12.8 0.11 12.5 0.7 2.9 3 1 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Fungal_trans_2 PF11951.8 KPA37069.1 - 0.0018 17.2 0.0 0.0033 16.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KPA37070.1 - 1.7e-69 233.6 13.2 1.7e-69 233.6 13.2 1.7 2 0 0 2 2 2 1 RTA1 like protein Caveolin PF01146.17 KPA37070.1 - 0.29 11.1 0.1 0.29 11.1 0.1 2.8 4 0 0 4 4 4 0 Caveolin Fungal_trans PF04082.18 KPA37071.1 - 5.6e-12 45.2 0.4 9.2e-12 44.5 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37071.1 - 4.5e-08 33.1 10.3 7.5e-08 32.4 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M14 PF00246.24 KPA37072.1 - 2.4e-84 283.6 0.1 2.9e-84 283.3 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KPA37072.1 - 0.055 13.9 0.0 0.24 11.8 0.0 2.1 2 0 0 2 2 2 0 Carboxypeptidase activation peptide AA_permease PF00324.21 KPA37073.1 - 3.2e-121 405.3 36.3 3.7e-121 405.1 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA37073.1 - 1.3e-37 129.6 43.7 1.8e-37 129.2 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease Transferase PF02458.15 KPA37076.1 - 1.3e-34 119.6 0.0 2.8e-27 95.5 0.0 3.4 2 1 0 2 2 2 2 Transferase family Hydrolase_like PF13242.6 KPA37077.1 - 0.00073 19.5 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KPA37077.1 - 0.0023 18.0 0.1 8.9 6.4 0.0 3.6 2 2 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA37077.1 - 0.0062 16.9 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4698 PF15769.5 KPA37078.1 - 2.2 7.2 3.3 3.3 6.7 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Glyco_hydro_16 PF00722.21 KPA37079.1 - 1.7e-13 50.4 0.1 2.7e-13 49.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KPA37079.1 - 4.3e-05 22.1 0.6 0.088 11.2 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 KPA37079.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) 3A PF00803.18 KPA37079.1 - 0.17 11.1 0.6 2.8 7.2 0.0 2.1 2 0 0 2 2 2 0 3A/RNA2 movement protein family HNH_2 PF13391.6 KPA37080.1 - 3.1e-11 43.3 0.1 6.9e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease ABC_tran PF00005.27 KPA37081.1 - 2.9e-47 160.6 0.0 5.6e-27 94.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KPA37081.1 - 4.6e-34 118.3 27.9 2.7e-27 96.1 12.5 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KPA37081.1 - 2.1e-10 40.4 2.5 0.0023 17.4 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPA37081.1 - 2e-07 31.1 0.1 0.0012 18.8 0.0 3.3 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPA37081.1 - 1.6e-06 27.8 2.4 0.001 18.8 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KPA37081.1 - 2.6e-06 28.1 1.8 0.0014 19.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KPA37081.1 - 6e-06 26.7 0.1 0.03 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KPA37081.1 - 9.1e-06 25.7 0.9 0.0095 15.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 KPA37081.1 - 1.5e-05 24.2 0.0 0.043 12.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 KPA37081.1 - 6.2e-05 23.3 1.1 0.037 14.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KPA37081.1 - 7.2e-05 22.8 0.1 0.15 12.1 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 KPA37081.1 - 0.00039 20.8 0.1 0.31 11.5 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KPA37081.1 - 0.00071 19.1 0.9 0.47 9.9 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KPA37081.1 - 0.00084 19.0 0.0 0.026 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPA37081.1 - 0.0012 19.0 0.0 0.033 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KPA37081.1 - 0.0017 18.5 0.2 0.11 12.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 KPA37081.1 - 0.0017 18.1 0.2 0.24 11.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KPA37081.1 - 0.0018 18.0 0.0 0.31 10.7 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain MeaB PF03308.16 KPA37081.1 - 0.0027 16.7 0.4 0.012 14.6 0.0 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 KPA37081.1 - 0.0029 17.0 0.3 1.4 8.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KPA37081.1 - 0.0035 17.1 0.2 7.2 6.3 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 KPA37081.1 - 0.0061 17.1 0.1 0.83 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KPA37081.1 - 0.0074 16.0 0.0 2.2 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KPA37081.1 - 0.011 14.9 0.0 3.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_10 PF12846.7 KPA37081.1 - 0.014 14.4 0.2 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.17 KPA37081.1 - 0.015 15.1 0.3 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 KPA37081.1 - 0.026 14.6 4.8 0.092 12.8 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KPA37081.1 - 0.035 13.0 2.9 2 7.2 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 KPA37081.1 - 0.044 14.2 0.1 11 6.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 KPA37081.1 - 0.045 13.3 2.7 0.11 12.1 0.7 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KPA37081.1 - 0.048 13.4 0.9 0.51 10.0 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 KPA37081.1 - 0.064 12.0 4.4 0.12 11.2 0.5 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KPA37081.1 - 0.088 12.1 0.1 2.1 7.5 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin SbcCD_C PF13558.6 KPA37081.1 - 0.1 12.8 0.0 17 5.7 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PBP_like PF12727.7 KPA37081.1 - 0.18 10.9 0.0 0.9 8.6 0.0 2.0 2 0 0 2 2 2 0 PBP superfamily domain TsaE PF02367.17 KPA37081.1 - 0.21 11.6 0.2 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KPA37081.1 - 0.28 11.1 0.7 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 KPA37081.1 - 1.2 9.0 4.9 5.2 7.0 0.6 3.1 3 0 0 3 3 3 0 NACHT domain Spc7 PF08317.11 KPA37082.1 - 0.0011 18.0 2.5 0.0015 17.5 2.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.11 KPA37082.1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Tmemb_cc2 PF10267.9 KPA37082.1 - 0.0021 17.3 0.3 0.0029 16.8 0.3 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein SHE3 PF17078.5 KPA37082.1 - 0.0025 17.6 0.1 0.0037 17.0 0.1 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 BLOC1_2 PF10046.9 KPA37082.1 - 0.0096 16.2 0.1 0.018 15.3 0.1 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 KPA37082.1 - 0.011 15.8 4.2 0.056 13.5 3.4 2.1 1 1 1 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 KPA37082.1 - 0.015 15.3 4.0 0.043 13.9 4.0 1.8 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 PRKG1_interact PF15898.5 KPA37082.1 - 0.021 15.7 0.8 0.076 13.9 0.9 1.9 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain CENP-F_leu_zip PF10473.9 KPA37082.1 - 0.025 14.6 2.8 0.044 13.8 2.8 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Not3 PF04065.15 KPA37082.1 - 0.026 14.0 0.7 0.042 13.3 0.7 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component KASH_CCD PF14662.6 KPA37082.1 - 0.026 14.3 1.5 0.044 13.6 1.5 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 KPA37082.1 - 0.027 14.9 1.5 0.056 13.9 1.5 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 KPA37082.1 - 0.029 14.1 1.2 0.06 13.1 0.9 1.6 2 0 0 2 2 1 0 Septum formation initiator Rootletin PF15035.6 KPA37082.1 - 0.03 14.3 1.0 0.047 13.7 1.0 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 KPA37082.1 - 0.054 14.0 5.9 0.4 11.2 5.6 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region CAP_N PF01213.19 KPA37082.1 - 0.068 12.7 0.4 0.11 12.0 0.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal XRCC4 PF06632.12 KPA37082.1 - 0.072 11.9 1.4 0.11 11.4 1.4 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 TolA_bind_tri PF16331.5 KPA37082.1 - 0.083 13.0 4.2 0.15 12.1 1.9 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation PikAIV_N PF18605.1 KPA37082.1 - 0.15 11.7 4.4 0.32 10.6 4.4 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain bZIP_2 PF07716.15 KPA37082.1 - 0.17 12.0 4.9 0.41 10.8 4.9 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Cnn_1N PF07989.11 KPA37082.1 - 0.38 10.9 3.9 1.3 9.3 2.4 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF5595 PF18077.1 KPA37082.1 - 0.92 9.6 6.3 0.45 10.6 2.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) FlaC_arch PF05377.11 KPA37082.1 - 0.92 9.9 2.8 16 6.0 0.5 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Med21 PF11221.8 KPA37082.1 - 1.3 9.3 5.8 3.5 7.9 5.9 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Zn_clus PF00172.18 KPA37083.1 - 2.9e-07 30.5 14.2 2.9e-07 30.5 14.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrophobin_2 PF06766.11 KPA37084.1 - 3.8e-23 81.2 9.3 4.6e-23 80.9 9.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin COesterase PF00135.28 KPA37085.1 - 1.1e-92 311.6 0.0 1.4e-92 311.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA37085.1 - 0.00044 20.2 2.7 0.002 18.0 0.0 3.1 4 1 0 4 4 4 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 KPA37085.1 - 0.033 13.0 0.3 0.048 12.5 0.3 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Peptidase_S9 PF00326.21 KPA37085.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans PF04082.18 KPA37086.1 - 4.6e-09 35.7 0.2 1.1e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain YihI PF04220.12 KPA37086.1 - 0.099 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Der GTPase activator (YihI) DUF2235 PF09994.9 KPA37087.1 - 1.4e-10 41.0 0.0 1.8e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Fungal_trans PF04082.18 KPA37088.1 - 2.5e-18 66.1 0.1 2.6e-16 59.4 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Fungal_trans PF04082.18 KPA37089.1 - 3.3e-19 69.0 0.7 1e-18 67.3 0.8 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37089.1 - 0.00042 20.4 6.0 0.00082 19.4 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_trans_2_3 PF13632.6 KPA37090.1 - 1.6e-52 178.3 2.5 1.6e-52 178.3 2.5 2.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KPA37090.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 ecTbetaR2 PF08917.10 KPA37090.1 - 0.14 12.1 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain RAMP4 PF06624.12 KPA37090.1 - 1.4 9.1 5.1 5.7 7.1 5.1 2.1 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 Glyco_hydro_16 PF00722.21 KPA37091.1 - 5.7e-16 58.5 1.1 1.1e-15 57.6 1.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WSC PF01822.19 KPA37092.1 - 4.8e-55 183.7 39.0 1.7e-21 76.2 9.6 3.4 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.11 KPA37092.1 - 6.2e-29 100.9 0.0 3.7e-27 95.1 0.0 2.8 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KPA37092.1 - 2.9e-23 82.0 0.0 7.1e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Sulfotransfer_1 PF00685.27 KPA37094.1 - 8.3e-48 163.2 0.0 1.1e-47 162.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPA37094.1 - 4.3e-07 30.6 0.1 0.022 15.1 0.1 3.1 1 1 1 2 2 2 2 Sulfotransferase family PAN_1 PF00024.26 KPA37095.1 - 5e-07 29.6 11.7 0.00032 20.6 1.7 4.0 4 0 0 4 4 4 3 PAN domain PAN_4 PF14295.6 KPA37095.1 - 0.00021 21.1 16.6 0.063 13.2 0.9 3.7 3 0 0 3 3 3 3 PAN domain Cutinase PF01083.22 KPA37096.1 - 1.2e-50 171.9 0.0 1.4e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KPA37096.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KPA37096.1 - 0.027 14.0 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.16 KPA37096.1 - 0.055 13.3 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Adeno_PV PF03910.13 KPA37097.1 - 2.2 6.9 6.1 3.1 6.4 6.1 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV ANAPC4_WD40 PF12894.7 KPA37098.1 - 3.2e-12 46.6 0.0 0.096 13.0 0.0 6.0 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPA37098.1 - 7.5e-09 36.1 16.0 0.21 12.5 0.0 7.8 8 0 0 8 8 7 3 WD domain, G-beta repeat Nup160 PF11715.8 KPA37098.1 - 1.7e-08 33.6 0.0 0.023 13.4 0.0 3.9 4 0 0 4 4 4 3 Nucleoporin Nup120/160 NACHT PF05729.12 KPA37098.1 - 3e-05 24.0 0.0 6.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KPA37098.1 - 5.1e-05 23.1 5.9 4.2 7.4 0.0 6.1 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KPA37098.1 - 5.7e-05 23.6 0.0 0.00029 21.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain eIF2A PF08662.11 KPA37098.1 - 0.00056 19.8 0.0 1.5 8.6 0.0 3.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KPA37098.1 - 0.011 14.7 0.0 3.6 6.5 0.0 4.2 5 0 0 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein APS_kinase PF01583.20 KPA37098.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KPA37098.1 - 0.019 14.2 0.0 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 KPA37098.1 - 0.023 15.2 0.0 0.058 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KPA37098.1 - 0.03 14.0 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KPA37098.1 - 0.076 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Torsin PIF1 PF05970.14 KPA37098.1 - 0.077 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase v110 PF01639.17 KPA37098.1 - 0.14 12.1 0.9 41 4.1 0.0 3.5 3 0 0 3 3 3 0 Viral family 110 CorA PF01544.18 KPA37099.1 - 0.00042 19.7 6.7 0.0014 18.0 6.7 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein WW PF00397.26 KPA37100.1 - 7.1e-19 67.6 6.2 1.2e-09 38.1 0.4 3.1 3 0 0 3 3 3 2 WW domain Nucleotid_trans PF03407.16 KPA37102.1 - 9.8e-06 25.7 0.1 1.8e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 KPA37102.1 - 6.1e-05 22.8 1.2 0.00011 22.0 1.2 1.4 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KPA37102.1 - 0.004 16.7 0.3 0.0076 15.8 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF273 SKA1 PF07160.12 KPA37103.1 - 0.0039 17.1 1.4 0.012 15.4 1.4 1.8 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 1 KxDL PF10241.9 KPA37103.1 - 0.11 12.7 1.4 0.96 9.8 0.6 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein Ank_2 PF12796.7 KPA37104.1 - 1.6e-28 99.1 0.1 1.1e-08 35.5 0.2 4.9 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA37104.1 - 3.1e-24 85.0 2.9 5.2e-06 26.9 0.0 6.3 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA37104.1 - 3.3e-20 70.0 1.6 0.017 15.6 0.0 8.7 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 KPA37104.1 - 4.3e-18 64.9 1.8 0.24 11.9 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KPA37104.1 - 9.5e-14 51.3 7.0 0.13 12.6 0.0 7.8 5 2 4 9 9 9 6 Ankyrin repeats (many copies) SET PF00856.28 KPA37106.1 - 0.18 12.2 0.0 0.32 11.4 0.0 1.5 2 0 0 2 2 2 0 SET domain Ribosomal_L26 PF16906.5 KPA37108.1 - 1.8e-38 130.9 1.5 2.3e-38 130.5 1.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KPA37108.1 - 3.7e-08 33.0 1.6 9.7e-08 31.7 1.6 1.7 1 0 0 1 1 1 1 KOW motif GHL5 PF14872.6 KPA37108.1 - 0.034 12.2 0.0 0.038 12.0 0.0 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 DUF1223 PF06764.11 KPA37108.1 - 0.045 13.8 0.0 0.055 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) CtaG_Cox11 PF04442.14 KPA37109.1 - 1.1e-60 204.1 0.0 1.6e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Pkinase PF00069.25 KPA37110.1 - 3.3e-11 43.1 0.0 4.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KPA37110.1 - 1.3e-07 31.4 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KPA37110.1 - 1.1e-06 28.8 0.8 4.4e-06 26.8 0.1 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KPA37110.1 - 2e-06 27.3 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KPA37110.1 - 0.00041 19.7 0.0 0.00055 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KPA37110.1 - 0.0015 18.1 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family NUDIX PF00293.28 KPA37112.1 - 3.3e-07 30.4 0.0 5.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain TIG_2 PF18020.1 KPA37112.1 - 0.067 13.8 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 TIG domain found in plexin Zn_clus PF00172.18 KPA37113.1 - 0.012 15.7 1.8 0.036 14.2 1.8 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FemAB_like PF04339.12 KPA37114.1 - 0.26 10.4 1.1 0.63 9.1 0.1 1.9 1 1 1 2 2 2 0 Peptidogalycan biosysnthesis/recognition HET PF06985.11 KPA37117.1 - 1.7e-10 41.4 5.0 3.3e-08 34.0 0.6 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) LysM PF01476.20 KPA37121.1 - 1.1e-17 63.9 2.4 0.0027 17.7 0.1 6.7 7 0 0 7 7 7 5 LysM domain SabA_adhesion PF18304.1 KPA37121.1 - 0.00031 20.1 4.3 0.013 14.7 0.1 3.0 3 0 0 3 3 3 2 SabA N-terminal extracellular adhesion domain CarbpepA_inh PF02977.15 KPA37121.1 - 0.03 14.1 1.8 6.7 6.6 0.2 3.6 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor DUF3128 PF11326.8 KPA37121.1 - 0.29 11.5 4.1 14 6.1 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF3128) adh_short PF00106.25 KPA37122.1 - 2.2e-34 118.6 0.0 2.9e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37122.1 - 1.6e-18 67.1 0.0 2.1e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA37122.1 - 5.1e-05 23.3 0.2 0.00012 22.1 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPA37122.1 - 6.5e-05 22.9 0.0 8.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA37122.1 - 0.00047 19.7 0.1 0.0017 17.9 0.1 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KPA37122.1 - 0.0027 18.0 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KPA37122.1 - 0.0041 17.7 0.2 0.0081 16.7 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KPA37122.1 - 0.0049 17.0 0.0 0.0093 16.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KPA37122.1 - 0.0069 16.5 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KPA37122.1 - 0.0072 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.19 KPA37122.1 - 0.046 13.0 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_Gly3P_dh_N PF01210.23 KPA37122.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KPA37122.1 - 0.13 12.5 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Eno-Rase_NADH_b PF12242.8 KPA37122.1 - 0.17 11.7 0.2 0.34 10.7 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Nrap_D3 PF17404.2 KPA37123.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Nrap protein domain 3 Macro PF01661.21 KPA37124.1 - 1.3e-25 89.8 0.0 2.5e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Macro domain DUF676 PF05057.14 KPA37124.1 - 0.0002 20.9 0.0 0.00056 19.5 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.12 KPA37124.1 - 0.017 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 KPA37124.1 - 0.037 13.6 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Abhydrolase_9 PF10081.9 KPA37124.1 - 0.045 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family PGAP1 PF07819.13 KPA37124.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein TniB PF05621.11 KPA37124.1 - 0.16 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Abhydrolase_6 PF12697.7 KPA37124.1 - 0.27 11.8 1.7 0.79 10.3 0.0 2.5 3 1 0 3 3 3 0 Alpha/beta hydrolase family Peptidase_S8 PF00082.22 KPA37126.1 - 1.1e-35 123.4 2.5 1.9e-35 122.6 2.5 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KPA37126.1 - 1e-06 29.3 0.1 7.3e-06 26.6 0.1 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I9 Glyco_hydro_61 PF03443.14 KPA37127.1 - 9.7e-48 162.8 0.1 9.7e-48 162.8 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KPA37127.1 - 1.8e-10 40.6 12.8 5.1e-10 39.1 12.8 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain ADH_N PF08240.12 KPA37128.1 - 1.6e-07 31.1 0.0 2.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA37128.1 - 2.9e-06 27.3 0.1 5.7e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPA37128.1 - 0.038 13.9 0.0 0.17 11.8 0.0 2.0 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Zn_clus PF00172.18 KPA37129.1 - 1.3e-09 38.0 6.2 2.2e-09 37.3 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.11 KPA37130.1 - 5.9e-13 48.5 0.4 1.9e-12 46.9 0.4 2.0 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KPA37130.1 - 3e-06 27.0 0.3 7.3e-05 22.5 0.4 2.6 2 0 0 2 2 2 1 Homeodomain zf-C2H2 PF00096.26 KPA37130.1 - 0.0026 18.1 24.7 0.0046 17.3 2.7 5.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA37130.1 - 0.0042 17.8 2.9 0.0042 17.8 2.9 5.4 6 0 0 6 6 6 1 C2H2-type zinc finger HTH_Tnp_Tc5 PF03221.16 KPA37130.1 - 0.008 16.2 1.3 4.3 7.5 0.0 4.3 5 0 0 5 5 5 1 Tc5 transposase DNA-binding domain Homez PF11569.8 KPA37130.1 - 0.032 13.7 0.6 0.15 11.5 0.6 2.1 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-C2H2_jaz PF12171.8 KPA37130.1 - 2.5 8.5 7.1 0.38 11.1 1.6 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FTH PF01827.27 KPA37132.1 - 0.034 13.9 0.0 0.13 12.0 0.0 1.9 1 1 1 2 2 2 0 FTH domain Isochorismatase PF00857.20 KPA37133.1 - 1.6e-42 145.7 0.1 1.8e-42 145.5 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family p450 PF00067.22 KPA37134.1 - 8.6e-59 199.5 0.0 1.1e-58 199.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KPA37135.1 - 1.1e-08 35.1 0.0 8.9e-06 25.6 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KPA37135.1 - 1.2e-08 35.5 0.0 4.2e-06 27.4 0.0 2.7 2 1 1 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA37135.1 - 4.8e-06 27.1 0.0 0.024 15.3 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain MTS PF05175.14 KPA37135.1 - 5e-05 22.9 0.0 8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KPA37135.1 - 0.00012 22.8 0.0 0.0042 17.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA37135.1 - 0.0004 20.2 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KPA37135.1 - 0.008 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 KPA37135.1 - 0.0082 15.5 0.0 0.047 13.0 0.0 2.1 3 0 0 3 3 3 1 O-methyltransferase domain Ubie_methyltran PF01209.18 KPA37135.1 - 0.0092 15.3 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KPA37135.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KPA37135.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) AMP-binding PF00501.28 KPA37136.1 - 5.1e-89 298.8 0.1 6.4e-89 298.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA37136.1 - 4.1e-24 85.4 2.0 9.1e-24 84.2 2.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KPA37136.1 - 3.8e-16 58.7 0.0 3.8e-16 58.7 0.0 2.7 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 KPA37136.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Dor1 PF04124.12 KPA37137.1 - 0.0039 15.9 1.4 0.0063 15.2 0.1 1.9 2 0 0 2 2 2 1 Dor1-like family SesA PF17107.5 KPA37137.1 - 0.049 13.8 0.9 1 9.5 0.0 2.9 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF948 PF06103.11 KPA37137.1 - 0.13 12.6 0.6 0.88 9.9 0.2 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MOSC PF03473.17 KPA37138.1 - 1.8e-14 53.9 0.0 2.6e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 MOSC domain adh_short PF00106.25 KPA37142.1 - 2.8e-23 82.4 0.0 1.1e-22 80.4 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37142.1 - 2.7e-14 53.3 0.0 9.9e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA37142.1 - 0.0013 18.6 0.0 0.0031 17.5 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA37142.1 - 0.0026 17.3 0.0 0.0078 15.7 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA37142.1 - 0.059 12.8 0.0 0.12 11.7 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 KPA37143.1 - 6.2e-09 35.3 1.2 1.1e-08 34.4 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37143.1 - 4e-06 26.8 7.8 4e-06 26.8 7.8 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arrestin_C PF02752.22 KPA37144.1 - 2.3e-06 28.1 0.0 4.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Cation_ATPase_C PF00689.21 KPA37146.1 - 2.2e-46 157.8 9.3 2.2e-46 157.8 9.3 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KPA37146.1 - 5.9e-36 123.7 0.2 5.9e-36 123.7 0.2 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KPA37146.1 - 1.2e-22 81.3 0.3 2.4e-22 80.3 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KPA37146.1 - 7.2e-19 67.7 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KPA37146.1 - 3e-10 39.6 0.1 7.9e-10 38.3 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPA37146.1 - 7.7e-05 22.6 0.3 0.00015 21.6 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Gemini_mov PF01708.16 KPA37146.1 - 0.077 12.8 0.2 0.7 9.7 0.1 2.4 2 0 0 2 2 2 0 Geminivirus putative movement protein HAD PF12710.7 KPA37146.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 KPA37147.1 - 8e-11 41.5 0.9 1.5e-10 40.6 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HalX PF08663.10 KPA37147.1 - 0.038 14.3 3.3 0.25 11.7 0.1 2.4 2 0 0 2 2 2 0 HalX domain DUF5024 PF16427.5 KPA37147.1 - 0.2 12.0 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5024) Cupin_3 PF05899.12 KPA37149.1 - 3.7e-07 29.8 0.0 5.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 KPA37149.1 - 7.8e-05 22.5 0.0 9.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.11 KPA37149.1 - 0.031 14.0 0.2 0.1 12.3 0.1 1.9 1 1 1 2 2 2 0 Cupin domain Cupin_6 PF12852.7 KPA37149.1 - 0.1 12.3 0.0 0.44 10.2 0.0 1.7 1 1 0 2 2 2 0 Cupin FAD_binding_3 PF01494.19 KPA37151.1 - 7.1e-31 107.7 0.0 9.1e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KPA37151.1 - 1.2e-07 31.4 0.0 5.8e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPA37151.1 - 3.7e-05 23.2 0.1 0.034 13.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 KPA37151.1 - 4.9e-05 23.1 0.0 6.3e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA37151.1 - 8e-05 22.8 0.1 0.00018 21.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPA37151.1 - 0.0001 21.2 0.0 0.0046 15.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KPA37151.1 - 0.00047 19.5 0.1 0.0061 15.8 0.1 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA37151.1 - 0.0011 19.5 0.0 0.035 14.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA37151.1 - 0.002 17.2 0.0 0.0057 15.7 0.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPA37151.1 - 0.0063 15.6 0.1 0.0091 15.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KPA37151.1 - 0.021 14.8 0.0 4 7.4 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KPA37151.1 - 0.028 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Glu_dehyd_C PF16912.5 KPA37151.1 - 0.033 13.7 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FAD_oxidored PF12831.7 KPA37151.1 - 0.036 13.4 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KPA37151.1 - 0.063 12.4 0.1 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KPA37151.1 - 0.068 12.0 0.1 0.19 10.5 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.10 KPA37151.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase adh_short PF00106.25 KPA37153.1 - 1.5e-39 135.5 0.1 2e-39 135.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37153.1 - 1.2e-36 126.4 0.0 1.8e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA37153.1 - 4.7e-11 42.9 0.1 7.8e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 KR domain TPP_enzyme_N PF02776.18 KPA37154.1 - 1.3e-31 109.5 0.1 2.2e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPA37154.1 - 3.8e-16 59.1 0.0 1.6e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KPA37154.1 - 4.9e-15 55.6 0.0 1.3e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KPA37154.1 - 0.001 18.1 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF1593 PF07632.11 KPA37157.1 - 8.4e-68 228.6 0.1 2.9e-47 161.3 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1593) ADH_zinc_N PF00107.26 KPA37157.1 - 6e-12 45.7 0.4 1.6e-11 44.3 0.4 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA37157.1 - 4.3e-06 26.6 0.3 5e-05 23.1 0.3 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain REJ PF02010.15 KPA37157.1 - 0.005 15.7 0.0 0.0086 14.9 0.0 1.3 1 0 0 1 1 1 1 REJ domain ADH_zinc_N_2 PF13602.6 KPA37157.1 - 0.065 14.3 0.0 2.7 9.0 0.0 2.6 1 1 0 2 2 2 0 Zinc-binding dehydrogenase p450 PF00067.22 KPA37158.1 - 1.9e-71 241.2 0.0 3.7e-71 240.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.17 KPA37159.1 - 4.9e-45 153.6 0.0 6.3e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RIH_assoc PF08454.11 KPA37159.1 - 0.034 14.0 0.0 0.16 11.8 0.0 2.1 1 1 0 1 1 1 0 RyR and IP3R Homology associated Borrelia_rep PF03183.13 KPA37159.1 - 9.5 6.4 6.9 22 5.3 0.7 2.5 2 0 0 2 2 2 0 Borrelia repeat protein p450 PF00067.22 KPA37160.1 - 2.3e-57 194.8 0.0 3e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HlyIII PF03006.20 KPA37161.1 - 1.2e-38 133.1 25.2 3.8e-30 105.3 15.2 2.3 2 0 0 2 2 2 2 Haemolysin-III related Prenyltrans PF00432.21 KPA37161.1 - 0.0037 17.0 0.0 1.8 8.4 0.2 3.2 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat HU-CCDC81_bac_2 PF18175.1 KPA37161.1 - 0.14 12.0 0.1 30 4.6 0.1 3.2 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 DUF5345 PF17280.2 KPA37163.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.5 4 0 0 4 4 4 0 Family of unknown function (DUF5345) AMP-binding PF00501.28 KPA37164.1 - 1.8e-80 270.6 0.0 3.8e-80 269.6 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme ECH_1 PF00378.20 KPA37165.1 - 9.2e-69 231.5 0.1 1e-68 231.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA37165.1 - 5.3e-33 114.9 0.1 2.6e-30 106.1 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Germane PF10646.9 KPA37165.1 - 0.025 15.4 0.4 0.13 13.0 0.2 2.0 2 0 0 2 2 2 0 Sporulation and spore germination SDH_sah PF01972.16 KPA37165.1 - 0.029 13.3 0.0 0.063 12.3 0.1 1.4 1 1 0 1 1 1 0 Serine dehydrogenase proteinase Hairpins PF04877.12 KPA37165.1 - 0.072 12.7 0.0 0.098 12.3 0.0 1.1 1 0 0 1 1 1 0 HrpZ Lactonase PF10282.9 KPA37166.1 - 0.0016 17.7 0.0 1.9 7.6 0.0 3.0 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller HET PF06985.11 KPA37167.1 - 3.8e-11 43.5 5.4 8.1e-09 36.0 0.5 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF2457 PF10446.9 KPA37169.1 - 0.14 11.3 5.1 0.17 11.0 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 KPA37169.1 - 0.25 10.6 4.7 0.33 10.2 4.7 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KPA37169.1 - 0.42 11.0 8.7 0.74 10.2 8.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Zn_clus PF00172.18 KPA37170.1 - 3.5e-08 33.4 14.1 7.2e-08 32.4 14.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 KPA37171.1 - 8.7e-24 84.6 0.0 1.8e-23 83.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA37171.1 - 0.0072 15.6 0.0 0.12 11.6 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KPA37171.1 - 0.0076 16.4 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KPA37171.1 - 0.096 12.3 0.0 0.22 11.1 0.0 1.5 1 1 1 2 2 2 0 Putative esterase Say1_Mug180 PF10340.9 KPA37171.1 - 0.13 11.1 0.0 0.48 9.2 0.0 1.9 2 1 0 2 2 2 0 Steryl acetyl hydrolase ATG16 PF08614.11 KPA37172.1 - 0.0017 18.6 2.1 0.0031 17.8 2.1 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) GAS PF13851.6 KPA37172.1 - 0.0018 17.7 1.8 0.0033 16.8 1.8 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4472 PF14739.6 KPA37172.1 - 0.0043 17.8 2.1 0.025 15.3 1.7 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4472) Leu_zip PF15294.6 KPA37172.1 - 0.0092 15.5 0.6 0.014 14.9 0.6 1.3 1 0 0 1 1 1 1 Leucine zipper TMF_DNA_bd PF12329.8 KPA37172.1 - 0.011 15.7 0.2 0.031 14.3 0.2 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.6 KPA37172.1 - 0.051 13.7 2.6 0.19 11.8 2.6 2.1 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF4515 PF14988.6 KPA37172.1 - 0.29 11.0 3.7 0.76 9.6 3.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) End3 PF12761.7 KPA37172.1 - 0.64 10.2 2.9 1.1 9.4 2.9 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Wtap PF17098.5 KPA37172.1 - 0.65 9.9 4.3 1.6 8.7 4.3 1.6 1 0 0 1 1 1 0 WTAP/Mum2p family DUF1515 PF07439.11 KPA37172.1 - 0.86 9.7 5.5 4.2 7.4 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) NYD-SP28_assoc PF14775.6 KPA37172.1 - 0.98 9.6 3.4 6.6 6.9 0.4 2.6 1 1 1 2 2 2 0 Sperm tail C-terminal domain Aa_trans PF01490.18 KPA37173.1 - 3e-71 240.3 31.1 3.9e-71 239.9 31.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Asp PF00026.23 KPA37174.1 - 7.5e-65 219.4 4.5 1e-64 219.0 4.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA37174.1 - 7.4e-12 45.9 12.2 1.4e-11 44.9 3.5 3.5 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Roughex PF06020.11 KPA37174.1 - 0.24 10.5 3.2 0.47 9.5 3.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DTHCT PF08070.11 KPA37174.1 - 1.3 9.8 5.2 0.82 10.4 2.8 1.9 2 0 0 2 2 2 0 DTHCT (NUC029) region Mfa1 PF17445.2 KPA37174.1 - 3.2 7.8 6.2 0.64 10.1 0.5 2.8 3 0 0 3 3 3 0 Mating factor A1 PPTA PF01239.22 KPA37175.1 - 4.3e-05 23.1 22.6 0.00087 18.9 0.8 5.1 6 0 0 6 6 6 3 Protein prenyltransferase alpha subunit repeat CHD5 PF04420.14 KPA37176.1 - 2.6e-62 209.4 2.0 3.2e-62 209.1 2.0 1.1 1 0 0 1 1 1 1 CHD5-like protein DUF2508 PF10704.9 KPA37176.1 - 0.017 15.2 0.6 0.035 14.3 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2508) ImpA_N PF06812.12 KPA37176.1 - 0.021 14.9 0.2 0.034 14.3 0.2 1.3 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system PcfJ PF14284.6 KPA37176.1 - 0.043 13.7 0.1 0.059 13.3 0.1 1.2 1 0 0 1 1 1 0 PcfJ-like protein DUF1515 PF07439.11 KPA37176.1 - 0.045 13.8 0.4 0.082 12.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF3368 PF11848.8 KPA37176.1 - 0.28 11.0 1.3 0.3 10.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) GRAB PF10375.9 KPA37178.1 - 3.9e-09 36.0 0.4 9.7e-09 34.8 0.1 1.9 2 0 0 2 2 2 1 GRIP-related Arf-binding domain Spc7 PF08317.11 KPA37178.1 - 0.00021 20.3 54.5 0.00055 18.9 29.3 2.8 1 1 1 2 2 2 2 Spc7 kinetochore protein Filament PF00038.21 KPA37178.1 - 0.00037 20.2 56.5 0.0031 17.1 17.6 2.9 1 1 1 2 2 2 2 Intermediate filament protein CENP-F_leu_zip PF10473.9 KPA37178.1 - 0.00056 19.9 64.7 0.014 15.5 18.8 3.8 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SIKE PF05769.11 KPA37178.1 - 0.00078 19.4 15.9 0.00078 19.4 15.9 3.8 2 1 1 3 3 2 1 SIKE family NPV_P10 PF05531.12 KPA37178.1 - 0.034 14.6 2.2 0.034 14.6 2.2 4.9 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.6 KPA37178.1 - 0.037 14.0 0.8 0.037 14.0 0.8 6.1 3 2 2 5 5 5 0 FlxA-like protein Lectin_N PF03954.14 KPA37178.1 - 0.049 13.4 28.0 0.058 13.1 3.8 3.9 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain Nup54_57_C PF18570.1 KPA37178.1 - 0.34 10.5 9.8 7.2 6.3 0.3 4.4 4 0 0 4 4 4 0 NUP57/Nup54 C-terminal domain DUF641 PF04859.12 KPA37178.1 - 0.39 11.0 43.4 1.2 9.5 7.0 4.6 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) HicB_lk_antitox PF15919.5 KPA37178.1 - 0.6 10.2 3.8 0.26 11.4 0.3 2.2 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system Baculo_PEP_C PF04513.12 KPA37178.1 - 0.98 9.5 22.3 0.36 10.9 1.6 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KPA37178.1 - 1.2 9.2 33.6 0.19 11.8 3.5 4.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF3138 PF11336.8 KPA37178.1 - 3.4 6.2 10.4 1.6 7.3 1.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3138) Occludin_ELL PF07303.13 KPA37178.1 - 3.7 8.3 33.9 0.76 10.5 2.5 5.2 1 1 4 5 5 5 0 Occludin homology domain HOOK PF05622.12 KPA37178.1 - 4.2 5.4 63.9 0.68 8.0 43.7 3.3 1 1 2 3 3 3 0 HOOK protein Golgin_A5 PF09787.9 KPA37178.1 - 5.2 6.4 65.3 0.074 12.5 26.9 3.8 2 1 2 4 4 4 0 Golgin subfamily A member 5 KASH_CCD PF14662.6 KPA37178.1 - 5.7 6.7 63.3 0.86 9.4 13.3 3.4 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF2935 PF11155.8 KPA37178.1 - 5.8 7.3 12.8 78 3.6 5.5 4.0 1 1 0 2 2 2 0 Domain of unknown function (DUF2935) Rootletin PF15035.6 KPA37178.1 - 7.1 6.6 57.3 0.69 9.9 22.4 3.7 2 2 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion ZYG-11_interact PF05884.12 KPA37178.1 - 7.2 5.9 14.9 2.2 7.6 2.3 2.7 1 1 2 3 3 3 0 Interactor of ZYG-11 Pkinase PF00069.25 KPA37179.1 - 1.9e-22 79.9 0.0 2.6e-14 53.2 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA37179.1 - 8.1e-14 51.5 0.0 7.3e-13 48.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Helicase_PWI PF18149.1 KPA37181.1 - 0.028 14.6 0.1 0.029 14.5 0.1 1.1 1 0 0 1 1 1 0 N-terminal helicase PWI domain MFS_1 PF07690.16 KPA37183.1 - 3.6e-38 131.4 13.7 3.6e-38 131.4 13.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA37183.1 - 7.5e-12 44.8 4.0 7.5e-12 44.8 4.0 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPA37183.1 - 0.0002 19.9 0.6 0.00032 19.3 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3392 PF11872.8 KPA37183.1 - 0.068 13.4 0.8 0.49 10.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) DUF2207 PF09972.9 KPA37185.1 - 0.0034 16.2 0.0 0.0042 15.9 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 KPA37185.1 - 0.0045 16.9 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Rax2 PF12768.7 KPA37185.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Herpes_gE PF02480.16 KPA37185.1 - 0.024 13.4 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PIRT PF15099.6 KPA37185.1 - 0.029 14.0 0.5 0.051 13.2 0.5 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Phage-Gp8 PF09215.10 KPA37185.1 - 0.047 12.7 0.1 0.057 12.5 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage T4, Gp8 SSP160 PF06933.11 KPA37185.1 - 0.32 9.1 8.0 0.41 8.8 8.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CAP_N PF01213.19 KPA37186.1 - 0.12 11.9 0.7 0.16 11.4 0.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAD_binding_3 PF01494.19 KPA37187.1 - 2e-20 73.4 0.0 7.4e-20 71.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA37187.1 - 0.00063 19.1 0.2 0.027 13.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPA37187.1 - 0.0024 17.2 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KPA37187.1 - 0.003 18.1 2.5 0.0041 17.6 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA37187.1 - 0.039 13.0 0.1 6.3 5.7 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein DUF1719 PF08224.11 KPA37187.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) DAO PF01266.24 KPA37187.1 - 0.11 12.1 0.0 0.76 9.3 0.0 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA37187.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CorA PF01544.18 KPA37188.1 - 0.013 14.8 0.1 0.013 14.8 0.1 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DnaI_N PF07319.11 KPA37188.1 - 0.1 13.3 1.5 1.3 9.8 0.0 2.8 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus ENTH PF01417.20 KPA37188.1 - 0.19 11.8 1.7 3.8 7.6 0.2 2.7 2 1 0 2 2 2 0 ENTH domain TMF_TATA_bd PF12325.8 KPA37188.1 - 1 9.6 9.7 0.75 10.0 0.1 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 KPA37188.1 - 9.9 6.7 11.6 0.26 11.8 1.3 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Clr5 PF14420.6 KPA37189.1 - 2.8e-11 43.5 0.7 5.8e-11 42.4 0.7 1.5 1 0 0 1 1 1 1 Clr5 domain Stimulus_sens_1 PF13756.6 KPA37192.1 - 0.089 13.4 0.7 0.23 12.0 0.1 2.0 2 0 0 2 2 2 0 Stimulus-sensing domain Phage_fiber_2 PF03406.13 KPA37192.1 - 0.22 11.1 1.1 24 4.6 0.0 2.6 2 0 0 2 2 2 0 Phage tail fibre repeat DUF2070 PF09843.9 KPA37193.1 - 1.5 7.0 6.8 2.4 6.4 6.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2614 PF11023.8 KPA37193.1 - 2.5 8.2 8.6 3.6 7.7 7.4 1.9 1 1 0 1 1 1 0 Zinc-ribbon containing domain adh_short PF00106.25 KPA37194.1 - 1.6e-24 86.5 0.1 3.5e-23 82.1 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37194.1 - 1.3e-17 64.2 0.0 4e-16 59.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA37194.1 - 0.0024 17.8 0.1 0.0047 16.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA37194.1 - 0.013 14.9 0.1 0.035 13.6 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KPA37195.1 - 1.3e-13 51.0 0.1 2e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA37195.1 - 5.9e-05 23.0 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KPA37195.1 - 0.0052 17.2 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KPA37195.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Helo_like_N PF17111.5 KPA37196.1 - 9.2e-09 35.0 7.2 2.9e-08 33.3 4.8 2.1 1 1 1 2 2 2 2 Fungal N-terminal domain of STAND proteins DUF5063 PF16702.5 KPA37196.1 - 3.1e-05 24.4 2.5 0.00033 21.1 0.8 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF5063) SesA PF17107.5 KPA37196.1 - 0.0002 21.6 6.7 0.00038 20.6 0.2 3.0 1 1 2 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases UPF0240 PF06784.11 KPA37196.1 - 0.00099 19.2 0.3 0.0018 18.3 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) DUF4795 PF16043.5 KPA37196.1 - 0.0014 18.2 7.0 0.0033 17.1 5.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) Rsm22 PF09243.10 KPA37196.1 - 0.0093 15.3 0.7 0.016 14.5 0.5 1.4 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Prominin PF05478.11 KPA37196.1 - 0.02 12.9 9.4 0.012 13.7 5.1 2.0 1 1 1 2 2 2 0 Prominin DUF2730 PF10805.8 KPA37196.1 - 0.037 14.1 7.7 18 5.5 0.0 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) Laminin_II PF06009.12 KPA37196.1 - 0.054 13.5 13.1 2.2 8.3 3.1 3.5 1 1 1 3 3 3 0 Laminin Domain II Clathrin PF00637.20 KPA37196.1 - 0.057 13.3 0.7 0.17 11.7 0.6 1.8 1 1 1 2 2 2 0 Region in Clathrin and VPS Syntaxin-6_N PF09177.11 KPA37196.1 - 0.058 13.9 10.2 2.9 8.5 1.5 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Fmp27_WPPW PF10359.9 KPA37196.1 - 0.084 11.7 9.4 0.26 10.1 0.2 2.1 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain FlaC_arch PF05377.11 KPA37196.1 - 0.086 13.2 6.9 26 5.3 0.2 4.5 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) Flt3_lig PF02947.14 KPA37196.1 - 0.097 12.9 4.6 2.4 8.3 0.2 3.2 1 1 2 4 4 4 0 flt3 ligand Trimer_CC PF08954.11 KPA37196.1 - 0.12 12.0 3.3 3.3 7.3 0.5 2.6 2 0 0 2 2 2 0 Trimerisation motif Spindle_Spc25 PF08234.12 KPA37196.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 DUF2451 PF10474.9 KPA37196.1 - 0.18 11.6 5.6 0.051 13.4 2.0 1.9 2 1 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) Filament PF00038.21 KPA37196.1 - 0.18 11.4 10.5 1.3 8.5 9.6 2.1 1 1 1 2 2 2 0 Intermediate filament protein Prefoldin_2 PF01920.20 KPA37196.1 - 0.19 11.7 8.0 0.3 11.0 0.1 3.6 1 1 2 3 3 3 0 Prefoldin subunit SF1-HH PF16275.5 KPA37196.1 - 0.22 11.8 3.5 0.38 11.1 1.0 2.7 2 1 0 2 2 2 0 Splicing factor 1 helix-hairpin domain DUF1664 PF07889.12 KPA37196.1 - 0.23 11.5 10.0 2 8.5 1.8 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) GAS PF13851.6 KPA37196.1 - 0.34 10.2 9.4 0.15 11.4 4.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 KPA37196.1 - 0.56 10.5 8.0 2.2 8.6 0.2 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) Spc24 PF08286.11 KPA37196.1 - 0.64 10.3 7.3 0.57 10.5 0.2 2.9 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 KPA37196.1 - 1.8 8.8 10.9 12 6.1 5.6 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PRKG1_interact PF15898.5 KPA37196.1 - 2.4 9.1 5.7 9.2 7.2 0.2 2.7 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4349 PF14257.6 KPA37196.1 - 3.9 6.8 9.9 0.58 9.6 6.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) COG2 PF06148.11 KPA37196.1 - 5.6 7.1 11.4 3.4 7.7 3.5 3.2 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Corona_S2 PF01601.16 KPA37196.1 - 7.9 4.8 10.3 10 4.5 7.9 2.0 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein Fasciclin PF02469.22 KPA37197.1 - 7.7e-38 129.6 0.2 6e-18 65.3 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain Med9 PF07544.13 KPA37198.1 - 0.19 11.8 2.5 7.7 6.7 0.4 2.9 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 NmrA PF05368.13 KPA37200.1 - 3.1e-40 138.2 0.0 4.6e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA37200.1 - 4e-09 36.6 0.1 9.6e-09 35.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KPA37200.1 - 2e-05 24.2 0.2 4.5e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA37200.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KPA37200.1 - 0.054 12.9 0.1 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase DUF3425 PF11905.8 KPA37201.1 - 2.2e-12 47.0 0.0 4.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.18 KPA37202.1 - 1e-07 32.0 6.8 2.4e-07 30.7 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.6 KPA37204.1 - 6.6e-10 39.3 0.0 6.3e-09 36.1 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPA37204.1 - 1.2e-09 38.3 0.0 1.9e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPA37204.1 - 2e-08 34.4 0.0 5.1e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPA37204.1 - 2e-05 24.7 0.0 3.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA37204.1 - 3.6e-05 23.9 0.0 7.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPA37204.1 - 0.025 14.6 0.2 0.1 12.6 0.1 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.18 KPA37205.1 - 4.3e-55 186.7 0.0 6.3e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KPA37205.1 - 3.5e-34 117.2 0.0 6.8e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Glyco_hydro_2_C PF02836.17 KPA37206.1 - 8.6e-105 350.2 0.1 1.1e-104 349.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KPA37206.1 - 7.5e-67 225.5 0.0 1.1e-66 224.9 0.0 1.2 1 0 0 1 1 1 1 Beta galactosidase small chain DUF4981 PF16353.5 KPA37206.1 - 1.1e-15 57.9 0.0 2.1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) DUF5550 PF17704.1 KPA37206.1 - 0.15 12.2 0.1 0.42 10.7 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5550) HET PF06985.11 KPA37208.1 - 4.7e-13 49.7 3.1 2e-10 41.2 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RepA1_leader PF08048.12 KPA37210.1 - 0.24 11.7 0.7 0.45 10.8 0.7 1.4 1 0 0 1 1 1 0 Tap RepA1 leader peptide FMO-like PF00743.19 KPA37211.1 - 2.2e-27 95.7 0.0 6.5e-22 77.6 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPA37211.1 - 4.4e-14 52.5 0.0 2.3e-11 43.5 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA37211.1 - 3.6e-12 46.1 0.0 4.5e-11 42.5 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPA37211.1 - 1.3e-11 44.3 0.0 6.1e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA37211.1 - 8.7e-06 25.8 0.0 0.00093 19.2 0.0 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPA37211.1 - 0.0055 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KPA37211.1 - 0.031 13.5 0.0 6.6 5.9 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KPA37211.1 - 0.092 12.3 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF2325 PF10087.9 KPA37211.1 - 0.17 12.0 0.0 0.59 10.3 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Arf PF00025.21 KPA37212.1 - 5.2e-22 78.1 0.0 1.2e-20 73.6 0.0 1.9 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 KPA37212.1 - 2.3e-10 40.2 0.0 3.1e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KPA37212.1 - 5.7e-07 29.8 0.0 1.1e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KPA37212.1 - 1.5e-05 25.0 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KPA37212.1 - 0.001 18.7 0.0 0.0013 18.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Hemopexin PF00045.19 KPA37212.1 - 0.014 15.3 0.3 0.035 14.1 0.3 1.7 1 0 0 1 1 1 0 Hemopexin AAA_33 PF13671.6 KPA37212.1 - 0.022 14.9 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KPA37212.1 - 0.094 11.7 0.1 5.6 5.9 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB 6PF2K PF01591.18 KPA37212.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Tmemb_14 PF03647.13 KPA37213.1 - 6.5e-25 87.7 6.9 7.6e-25 87.5 6.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Gram_pos_anchor PF00746.21 KPA37213.1 - 1 9.3 0.1 1 9.3 0.1 3.1 4 0 0 4 4 4 0 LPXTG cell wall anchor motif LIP PF03583.14 KPA37214.1 - 3.4e-59 200.5 0.4 4.8e-59 200.0 0.4 1.1 1 0 0 1 1 1 1 Secretory lipase Cutinase PF01083.22 KPA37214.1 - 0.11 12.5 0.3 2.3 8.2 0.1 2.7 3 0 0 3 3 3 0 Cutinase Sulfotransfer_4 PF17784.1 KPA37215.1 - 4e-56 190.2 0.1 4.7e-56 190.0 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPA37215.1 - 0.059 13.8 0.1 0.17 12.2 0.1 1.8 1 1 1 2 2 2 0 Sulfotransferase family MFS_1 PF07690.16 KPA37216.1 - 5.7e-43 147.2 21.2 5.7e-43 147.2 21.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA37216.1 - 2.7e-15 56.2 7.8 2.7e-15 56.2 7.8 2.4 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KPA37216.1 - 0.0019 16.6 2.7 0.0019 16.6 2.7 2.3 3 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family UNC-93 PF05978.16 KPA37216.1 - 0.0083 15.9 0.6 0.0083 15.9 0.6 1.9 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 RseC_MucC PF04246.12 KPA37216.1 - 8.3 6.4 9.5 11 5.9 1.0 3.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DAO PF01266.24 KPA37217.1 - 1.7e-32 113.4 0.0 2e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA37217.1 - 5.6e-05 23.3 0.0 0.0003 20.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPA37217.1 - 0.00048 19.5 0.0 0.00078 18.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPA37217.1 - 0.0051 16.2 0.1 1.7 7.8 0.1 2.6 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KPA37217.1 - 0.0061 15.8 0.0 0.08 12.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KPA37217.1 - 0.047 13.2 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 KPA37217.1 - 0.062 12.0 0.0 2.4 6.8 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KPA37217.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KPA37217.1 - 0.08 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KPA37217.1 - 0.088 13.1 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.19 KPA37217.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Chromate_transp PF02417.15 KPA37218.1 - 4.7e-60 202.3 32.8 7.4e-37 126.9 12.0 2.4 3 0 0 3 3 3 2 Chromate transporter RBP_receptor PF14752.6 KPA37218.1 - 0.062 11.9 0.2 0.43 9.1 0.2 2.1 2 0 0 2 2 2 0 Retinol binding protein receptor Glyco_hydro_61 PF03443.14 KPA37219.1 - 2.1e-62 210.7 0.3 2.8e-62 210.3 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAD_binding_3 PF01494.19 KPA37226.1 - 2.8e-18 66.3 0.0 6.9e-18 65.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.11 KPA37226.1 - 2.5e-09 37.0 0.0 7.7e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 KPA37226.1 - 9.4e-07 28.3 0.9 5.3e-06 25.9 0.9 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA37226.1 - 1.3e-06 28.5 0.6 3.3e-06 27.2 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPA37226.1 - 9.5e-06 24.9 1.3 2e-05 23.9 1.3 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KPA37226.1 - 1.5e-05 24.8 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KPA37226.1 - 0.0026 16.7 0.2 0.017 14.0 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 KPA37226.1 - 0.0029 17.0 0.2 0.0048 16.3 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA37226.1 - 0.011 14.4 0.3 0.017 13.8 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KPA37226.1 - 0.012 16.2 0.1 0.012 16.2 0.1 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KPA37226.1 - 0.019 14.6 0.5 0.034 13.8 0.5 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KPA37226.1 - 0.019 14.0 0.7 0.028 13.5 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KPA37226.1 - 0.033 13.5 0.9 0.094 12.0 0.2 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KPA37226.1 - 0.089 12.0 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KPA37226.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPA37226.1 - 0.11 11.8 0.6 0.37 10.0 0.1 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase PepX_C PF08530.10 KPA37227.1 - 5.4e-45 154.1 0.4 8.3e-45 153.5 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KPA37227.1 - 3.7e-41 141.5 0.4 5e-41 141.1 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KPA37227.1 - 0.025 13.8 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ephrin_rec_like PF07699.13 KPA37228.1 - 0.38 10.6 3.0 1.3 8.8 0.5 2.2 1 1 1 2 2 2 0 Putative ephrin-receptor like Ferritin_2 PF13668.6 KPA37229.1 - 7.1e-43 146.1 0.8 1.2e-42 145.3 0.8 1.4 1 0 0 1 1 1 1 Ferritin-like domain DUF455 PF04305.14 KPA37229.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF455) LigB PF02900.18 KPA37230.1 - 2.2e-14 53.2 0.0 2.6e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans PF04082.18 KPA37231.1 - 3.5e-10 39.4 0.0 5.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPA37231.1 - 0.0021 18.4 1.3 0.008 16.6 1.3 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA37231.1 - 0.027 15.3 0.7 0.15 13.0 0.7 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger Chlor_dismutase PF06778.12 KPA37231.1 - 0.038 13.6 0.1 1.8 8.1 0.0 2.6 3 0 0 3 3 3 0 Chlorite dismutase Zn_clus PF00172.18 KPA37231.1 - 1.8 8.8 9.5 0.38 10.9 4.6 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CVNH PF08881.10 KPA37232.1 - 3.7e-26 91.7 0.0 4.1e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 CVNH domain Acyl-CoA_dh_1 PF00441.24 KPA37237.1 - 9e-23 81.1 0.8 2e-22 80.0 0.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPA37237.1 - 2.5e-18 66.8 0.0 5.6e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KPA37237.1 - 2.7e-07 30.9 0.3 5.2e-07 30.0 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPA37237.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Trypsin PF00089.26 KPA37238.1 - 5.3e-10 39.5 0.1 1.2e-09 38.3 0.1 1.6 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KPA37238.1 - 2.3e-05 25.3 0.0 6.1e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Nodulin_late PF07127.11 KPA37238.1 - 0.044 14.1 0.3 0.47 10.8 0.1 2.3 2 0 0 2 2 2 0 Late nodulin protein MFS_1 PF07690.16 KPA37239.1 - 2.7e-37 128.5 21.9 3.2e-37 128.3 21.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_4 PF01565.23 KPA37240.1 - 1.2e-35 122.3 0.0 2e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.18 KPA37240.1 - 2.1e-17 63.1 3.6 2.1e-17 63.1 3.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain PE PF00934.20 KPA37240.1 - 0.025 14.9 0.8 0.063 13.6 0.8 1.6 1 0 0 1 1 1 0 PE family MFS_1 PF07690.16 KPA37241.1 - 1.7e-34 119.3 29.0 2.7e-34 118.6 29.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GIY-YIG PF01541.24 KPA37242.1 - 0.13 12.5 0.3 0.27 11.5 0.3 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain BTB PF00651.31 KPA37243.1 - 4e-14 52.8 0.0 6.2e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain NTS PF15447.6 KPA37243.1 - 0.027 14.9 0.1 0.083 13.4 0.1 1.8 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 Malectin_like PF12819.7 KPA37244.1 - 0.13 11.4 0.1 0.15 11.2 0.1 1.0 1 0 0 1 1 1 0 Malectin-like domain Glyco_hydro_76 PF03663.14 KPA37245.1 - 2.1e-30 106.4 1.4 2.1e-30 106.4 1.4 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Fungal_trans PF04082.18 KPA37246.1 - 1.3e-16 60.5 0.0 2.9e-16 59.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37246.1 - 0.0003 20.8 5.1 0.00057 20.0 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 KPA37246.1 - 0.039 12.4 0.0 0.058 11.9 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Trp_DMAT PF11991.8 KPA37247.1 - 7.9e-106 354.5 0.0 9e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.28 KPA37248.1 - 1e-144 482.3 0.0 2.7e-71 240.4 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KPA37248.1 - 9.6e-86 288.2 0.0 2.5e-46 158.3 0.0 2.1 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KPA37248.1 - 2.3e-23 82.3 0.9 8.4e-08 32.5 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KPA37248.1 - 3.7e-08 34.2 0.0 0.00045 21.1 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Methyltransf_2 PF00891.18 KPA37249.1 - 1.1e-29 103.3 0.0 1.5e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KPA37249.1 - 0.0046 16.9 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 KPA37249.1 - 0.089 12.6 0.0 1.2 8.9 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain FANCI_S4 PF14678.6 KPA37249.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 4 MFS_1 PF07690.16 KPA37250.1 - 5.6e-27 94.6 44.8 1.2e-26 93.5 41.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_Z PF16594.5 KPA37250.1 - 0.17 11.4 5.9 0.16 11.5 1.5 2.9 2 1 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated CDH-cyt PF16010.5 KPA37251.1 - 1.5e-51 174.7 0.3 1.5e-51 174.7 0.3 2.0 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KPA37251.1 - 1.2e-33 116.8 0.0 3e-33 115.5 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA37251.1 - 3.2e-22 79.6 0.8 7e-22 78.5 0.8 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPA37251.1 - 2.3e-07 30.2 0.5 1.5e-06 27.5 0.6 2.1 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPA37251.1 - 3.4e-06 26.0 0.0 0.00024 19.9 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KPA37251.1 - 3.9e-05 23.0 0.0 0.0016 17.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA37251.1 - 4.7e-05 23.1 0.1 0.025 14.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA37251.1 - 0.00052 20.2 0.0 0.0067 16.6 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPA37251.1 - 0.0016 17.8 0.0 0.015 14.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA37251.1 - 0.0039 16.3 0.0 0.0073 15.4 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KPA37251.1 - 0.0051 16.2 0.1 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPA37251.1 - 0.052 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KPA37251.1 - 0.055 12.7 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KPA37251.1 - 0.1 13.2 0.2 2.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 KPA37252.1 - 5.3e-60 203.5 0.0 6.6e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cas_DxTHG PF09455.10 KPA37252.1 - 0.056 13.0 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Esterase PF00756.20 KPA37253.1 - 5.9e-10 39.2 0.0 3e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KPA37253.1 - 0.001 18.4 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPA37253.1 - 0.0014 18.2 0.0 0.0034 16.9 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KPA37253.1 - 0.057 14.0 0.0 0.095 13.3 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 KPA37254.1 - 2.4e-18 66.2 50.9 4.5e-10 39.0 26.5 2.9 2 1 2 4 4 4 3 Major Facilitator Superfamily TRI12 PF06609.13 KPA37254.1 - 1.3e-07 30.5 17.1 1.5e-07 30.2 17.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FeoB_associated PF12669.7 KPA37254.1 - 0.027 14.9 4.6 27 5.3 0.0 4.2 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Mitofilin PF09731.9 KPA37254.1 - 0.066 12.0 0.0 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3185 PF11381.8 KPA37254.1 - 0.24 11.4 5.0 3.2 7.8 0.6 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Fungal_trans PF04082.18 KPA37255.1 - 1e-19 70.6 0.0 2.1e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 KPA37257.1 - 4.5e-17 62.4 0.0 5.7e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA37257.1 - 1.7e-12 47.6 0.0 2.5e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA37257.1 - 4.2e-12 46.1 0.0 5.3e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KPA37257.1 - 3e-05 24.2 0.0 3.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA37257.1 - 0.00027 20.8 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KPA37257.1 - 0.00027 21.0 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KPA37257.1 - 0.00029 21.0 0.0 0.00034 20.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KPA37257.1 - 0.0019 18.9 0.0 0.0022 18.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KPA37257.1 - 0.015 15.1 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 KPA37257.1 - 0.06 13.4 0.0 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KPA37259.1 - 1.7e-33 116.0 48.4 1.7e-33 116.0 48.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CBM_4_9 PF02018.17 KPA37261.1 - 5e-05 23.6 0.0 5e-05 23.6 0.0 2.6 2 1 0 2 2 2 1 Carbohydrate binding domain RIFIN PF02009.16 KPA37261.1 - 1.6 8.6 8.2 2.2 8.1 8.2 1.2 1 0 0 1 1 1 0 Rifin Imm2 PF14426.6 KPA37262.1 - 0.06 13.4 2.4 0.075 13.1 0.2 2.2 2 0 0 2 2 2 0 Immunity protein Imm2 DUF1542 PF07564.11 KPA37262.1 - 0.21 11.7 0.6 0.4 10.8 0.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) RHS_repeat PF05593.14 KPA37264.1 - 3.8e-22 78.4 67.1 0.00047 20.6 0.2 15.5 11 4 5 17 17 17 10 RHS Repeat DUF5640 PF18692.1 KPA37264.1 - 0.094 12.8 1.0 0.45 10.6 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5640) Glyco_hydro_cc PF11790.8 KPA37265.1 - 4.2e-45 154.2 0.2 5.6e-45 153.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core NosL PF05573.12 KPA37265.1 - 0.064 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 NosL Cupin_7 PF12973.7 KPA37267.1 - 2.9e-08 33.5 0.1 5.2e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 KPA37267.1 - 0.0032 17.2 0.6 0.0079 15.9 0.6 1.7 1 1 0 1 1 1 1 Cupin domain S-layer PF07752.11 KPA37267.1 - 0.053 12.6 0.2 0.31 10.1 0.0 1.9 2 0 0 2 2 2 0 S-layer protein RTA1 PF04479.13 KPA37268.1 - 2.2e-63 213.6 13.4 2.2e-63 213.6 13.4 1.5 2 0 0 2 2 2 1 RTA1 like protein YrhK PF14145.6 KPA37268.1 - 0.64 9.9 13.0 0.15 12.0 4.2 3.1 2 1 0 2 2 2 0 YrhK-like protein Zn_clus PF00172.18 KPA37269.1 - 1.6e-06 28.1 5.3 2.8e-06 27.3 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_3 PF07969.11 KPA37270.1 - 4.5e-09 36.3 0.0 5e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KPA37270.1 - 1.4e-07 31.2 0.0 1.6e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KPA37271.1 - 1.7e-05 24.3 0.1 2.3e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPA37271.1 - 0.0033 17.0 0.1 0.0055 16.2 0.0 1.4 2 0 0 2 2 2 1 Amidohydrolase family DUF1972 PF09314.11 KPA37272.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) FAD_binding_4 PF01565.23 KPA37273.1 - 4.1e-14 52.5 1.0 8.8e-14 51.4 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N PF00107.26 KPA37273.1 - 7e-08 32.5 0.7 2.1e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA37273.1 - 7.2e-07 29.1 0.0 1.7e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KPA37274.1 - 2.6e-32 111.9 0.0 4.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37274.1 - 3.9e-22 79.0 0.0 5.7e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KPA37274.1 - 2.1e-05 24.0 0.0 0.00066 19.1 0.0 2.2 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) GMC_oxred_N PF00732.19 KPA37275.1 - 1.8e-58 198.3 0.0 2.3e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA37275.1 - 1.1e-31 110.3 0.1 2.1e-31 109.4 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KPA37275.1 - 0.00013 21.1 0.1 0.00035 19.7 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KPA37275.1 - 0.00041 20.0 0.2 0.017 14.7 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA37275.1 - 0.00085 18.6 0.1 0.025 13.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA37275.1 - 0.0023 16.7 0.0 0.16 10.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KPA37275.1 - 0.0023 17.1 0.4 1.6 7.7 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KPA37275.1 - 0.0026 16.9 0.2 0.55 9.2 0.9 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KPA37275.1 - 0.0037 16.6 0.5 2.4 7.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA37275.1 - 0.0084 16.3 0.2 0.022 15.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain CBM_11 PF03425.13 KPA37275.1 - 0.012 15.5 0.5 0.031 14.1 0.5 1.5 1 1 0 1 1 1 0 Carbohydrate binding domain (family 11) EHN PF06441.12 KPA37275.1 - 0.049 14.0 1.3 2.2 8.7 0.0 3.0 3 1 0 3 3 3 0 Epoxide hydrolase N terminus FAD_oxidored PF12831.7 KPA37275.1 - 0.09 12.1 1.9 1.4 8.2 0.9 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF885 PF05960.11 KPA37276.1 - 1.2e-49 170.4 0.2 1.9e-49 169.8 0.2 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) MFS_1 PF07690.16 KPA37277.1 - 3.9e-31 108.3 47.8 3.9e-31 108.3 47.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KPA37278.1 - 6.9e-22 77.8 0.7 2.9e-10 39.5 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37278.1 - 0.0013 18.8 16.7 0.0025 17.9 16.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPA37279.1 - 1.9e-12 46.8 30.1 1.9e-12 46.8 30.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily SPC25 PF06703.11 KPA37279.1 - 0.12 12.1 1.2 0.28 10.9 1.2 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ank_2 PF12796.7 KPA37280.1 - 8.6e-20 71.1 3.0 4.8e-12 46.3 0.3 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA37280.1 - 3.7e-13 49.7 0.1 1.3e-06 28.8 0.0 4.1 2 1 3 5 5 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KPA37280.1 - 1.5e-11 44.2 1.1 0.0024 18.2 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat NACHT PF05729.12 KPA37280.1 - 1.9e-11 44.2 0.1 3.8e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 KPA37280.1 - 1.8e-10 40.9 0.3 6.2e-06 26.4 0.1 4.6 1 1 3 4 4 4 2 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KPA37280.1 - 1e-08 34.8 0.3 3e-08 33.2 0.3 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_3 PF13606.6 KPA37280.1 - 1.1e-08 34.6 0.1 0.012 16.1 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat AAA_22 PF13401.6 KPA37280.1 - 1.2e-05 25.6 0.1 3.4e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA37280.1 - 0.00016 22.1 0.3 0.00047 20.6 0.3 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KPA37280.1 - 0.002 18.1 0.0 0.13 12.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KPA37280.1 - 0.027 14.4 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KPA37280.1 - 0.077 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KPA37280.1 - 0.078 13.4 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 KPA37280.1 - 0.11 11.7 0.3 9.3 5.4 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain DUF3237 PF11578.8 KPA37281.1 - 0.00011 22.1 0.1 0.00024 21.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) Hexokinase_2 PF03727.16 KPA37282.1 - 8e-73 244.8 0.0 1.5e-72 243.9 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 KPA37282.1 - 8.3e-62 208.6 0.2 1.2e-61 208.1 0.2 1.3 1 0 0 1 1 1 1 Hexokinase HCO3_cotransp PF00955.21 KPA37283.1 - 1.4e-70 238.6 13.1 3.3e-41 141.7 8.8 2.2 1 1 1 2 2 2 2 HCO3- transporter family GMC_oxred_N PF00732.19 KPA37284.1 - 3.5e-64 217.0 0.0 5.3e-64 216.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA37284.1 - 1.8e-31 109.6 0.0 3.1e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KPA37284.1 - 0.0001 21.5 0.7 0.00016 20.8 0.7 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPA37284.1 - 0.021 13.9 1.0 0.49 9.4 1.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KPA37284.1 - 0.044 13.0 0.9 0.084 12.1 0.1 1.8 2 0 0 2 2 2 0 Thi4 family CAP_N PF01213.19 KPA37286.1 - 0.059 12.8 0.1 0.075 12.5 0.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TERF2_RBM PF16772.5 KPA37287.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif Peptidase_S8 PF00082.22 KPA37289.1 - 4e-14 52.6 0.0 1e-13 51.3 0.0 1.6 1 1 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 KPA37290.1 - 2.8e-47 159.2 7.3 1.7e-17 63.7 0.0 5.5 3 1 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA37290.1 - 3.4e-39 132.7 1.8 2.1e-08 34.6 0.0 7.5 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KPA37290.1 - 1.9e-33 113.4 11.1 0.00041 20.7 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 KPA37290.1 - 2.9e-33 110.2 1.1 0.00035 20.8 0.0 9.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KPA37290.1 - 2.3e-29 101.0 4.6 5.9e-07 29.7 0.0 7.1 2 2 4 6 6 6 6 Ankyrin repeats (many copies) NACHT PF05729.12 KPA37290.1 - 3.8e-10 39.9 0.3 7.2e-10 39.0 0.3 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KPA37290.1 - 5.7e-08 32.3 0.1 1.4e-07 31.0 0.1 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.6 KPA37290.1 - 5.8e-06 26.6 0.2 1.6e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA37290.1 - 2.1e-05 25.0 2.5 5.8e-05 23.5 0.9 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KPA37290.1 - 2.8e-05 24.2 0.2 0.0028 17.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KPA37290.1 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KPA37290.1 - 0.059 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 KPA37290.1 - 0.069 12.4 0.2 5.2 6.2 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.22 KPA37290.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF1843 PF08898.10 KPA37290.1 - 0.24 11.9 1.1 1.7 9.2 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) FAD_binding_4 PF01565.23 KPA37292.1 - 5.8e-21 74.7 0.0 2.2e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain COesterase PF00135.28 KPA37293.1 - 2.4e-11 43.2 0.0 1.4e-08 34.0 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_M57 PF12388.8 KPA37294.1 - 0.0097 15.5 0.4 1.8 8.2 0.1 2.2 1 1 1 2 2 2 2 Dual-action HEIGH metallo-peptidase AMP-binding PF00501.28 KPA37298.1 - 1.1e-79 268.0 0.0 1.5e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA37298.1 - 1.9e-14 54.4 0.0 3.7e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain APH PF01636.23 KPA37299.1 - 2.8e-10 40.5 0.0 7.2e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPA37299.1 - 0.024 14.2 0.1 0.059 12.9 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF1704 PF08014.11 KPA37300.1 - 0.011 14.8 5.4 0.014 14.5 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) MarR_2 PF12802.7 KPA37300.1 - 0.032 14.1 0.4 0.059 13.3 0.4 1.5 1 0 0 1 1 1 0 MarR family MarR PF01047.22 KPA37300.1 - 0.065 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 MarR family Spc24 PF08286.11 KPA37300.1 - 0.093 13.0 9.1 2.2 8.6 6.9 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Pex19 PF04614.12 KPA37300.1 - 0.12 12.2 9.3 0.14 11.9 9.3 1.2 1 0 0 1 1 1 0 Pex19 protein family YtxH PF12732.7 KPA37300.1 - 1 10.0 5.4 3.9 8.1 5.4 2.0 1 1 0 1 1 1 0 YtxH-like protein MRP-S31 PF15433.6 KPA37300.1 - 1.8 8.2 10.7 2.1 7.9 10.7 1.2 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 TMPIT PF07851.13 KPA37300.1 - 2.1 7.5 5.4 3.6 6.8 5.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.9 KPA37300.1 - 7.8 5.5 12.3 9.9 5.1 12.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MFS_1 PF07690.16 KPA37303.1 - 1.5e-40 139.2 35.4 1.5e-40 139.2 35.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CHAT PF12770.7 KPA37304.1 - 4.1e-30 105.2 0.0 7.2e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KPA37304.1 - 0.00082 19.2 12.1 1.8 8.5 0.0 6.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPA37304.1 - 0.0016 18.5 0.4 78 3.9 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Bac_chlorC PF02043.17 KPA37304.1 - 0.086 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein Cas_DxTHG PF09455.10 KPA37304.1 - 0.087 12.4 0.1 12 5.3 0.0 3.1 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family PNP_UDP_1 PF01048.20 KPA37305.1 - 3.9e-09 36.1 0.4 1.3e-08 34.4 0.4 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Peptidase_C14 PF00656.22 KPA37306.1 - 8.8e-11 42.2 0.1 5.5e-05 23.2 0.2 2.3 1 1 1 2 2 2 2 Caspase domain DUF4384 PF14326.6 KPA37306.1 - 0.098 12.8 0.0 0.79 9.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) Peptidase_M14 PF00246.24 KPA37307.1 - 9e-14 52.0 0.0 1.4e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KPA37307.1 - 0.0067 15.5 0.1 0.19 10.8 0.0 2.2 2 0 0 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family Aminotran_3 PF00202.21 KPA37308.1 - 5.8e-92 308.4 0.0 7.4e-92 308.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KPA37308.1 - 7.6e-05 22.0 0.2 0.0003 20.1 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II NUC130_3NT PF08158.12 KPA37308.1 - 0.02 15.2 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 NUC130/3NT domain Fungal_trans_2 PF11951.8 KPA37309.1 - 2e-18 66.4 2.7 1e-10 41.0 0.3 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37309.1 - 1.3e-05 25.2 8.5 2.4e-05 24.3 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 KPA37311.1 - 5.4e-20 71.3 5.6 1.1e-19 70.3 5.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA37311.1 - 2.1e-14 53.6 0.0 4.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPA37311.1 - 0.00014 21.2 0.1 0.00027 20.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KPA37311.1 - 0.0028 17.0 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KPA37311.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KPA37311.1 - 0.076 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MAP17 PF15807.5 KPA37312.1 - 1.2 9.4 7.1 0.42 10.8 3.9 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 BTB PF00651.31 KPA37313.1 - 0.018 15.3 0.1 0.67 10.2 0.0 2.8 3 0 0 3 3 3 0 BTB/POZ domain DnaJ_CXXCXGXG PF00684.19 KPA37317.1 - 0.00023 21.5 0.5 0.00026 21.3 0.5 1.2 1 0 0 1 1 1 1 DnaJ central domain TackOD1 PF18551.1 KPA37317.1 - 0.078 12.6 0.1 0.095 12.4 0.1 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 tRNA_bind_3 PF17176.4 KPA37318.1 - 0.02 15.2 0.7 0.12 12.7 0.2 2.3 2 0 0 2 2 2 0 tRNA-binding domain DivIC PF04977.15 KPA37318.1 - 0.22 11.3 2.5 0.18 11.6 0.3 2.0 2 0 0 2 2 2 0 Septum formation initiator F-box-like PF12937.7 KPA37320.1 - 0.00046 20.0 0.3 0.0011 18.8 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA37320.1 - 0.00048 19.9 0.1 0.00097 19.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KPA37320.1 - 0.031 14.2 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 F-box TMEM251 PF15190.6 KPA37320.1 - 0.086 12.8 0.4 0.19 11.7 0.3 1.5 1 1 0 1 1 1 0 Transmembrane protein 251 Sulfotransfer_4 PF17784.1 KPA37324.1 - 0.12 12.1 1.0 0.24 11.2 1.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain Ank_2 PF12796.7 KPA37326.1 - 1.3e-49 166.7 0.1 1.4e-17 64.1 0.1 4.6 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA37326.1 - 3.1e-34 113.1 0.1 0.0014 19.0 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 KPA37326.1 - 3.2e-34 115.9 0.9 0.00017 21.9 0.0 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 KPA37326.1 - 1.2e-30 105.5 0.1 4.1e-07 30.4 0.0 6.7 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA37326.1 - 2.1e-28 98.0 0.6 2.1e-06 27.9 0.0 7.1 3 2 2 7 7 7 6 Ankyrin repeats (many copies) HET PF06985.11 KPA37326.1 - 1.3e-09 38.6 5.8 8.3e-08 32.7 0.9 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3881 PF12997.7 KPA37326.1 - 0.17 11.1 0.2 0.9 8.7 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3881) MAP7 PF05672.11 KPA37327.1 - 0.094 12.4 1.0 0.16 11.6 1.0 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DIT1_PvcA PF05141.12 KPA37328.1 - 9.7e-82 274.5 0.0 2.5e-81 273.2 0.0 1.7 2 0 0 2 2 2 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.28 KPA37328.1 - 8.6e-15 54.2 0.0 1.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 KPA37328.1 - 3.2e-09 35.9 0.0 6.6e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Transferase family PP-binding PF00550.25 KPA37328.1 - 1.4e-05 25.4 0.1 4.2e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site p450 PF00067.22 KPA37329.1 - 1e-40 139.9 0.0 1.3e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KPA37330.1 - 3.8e-33 114.9 0.0 5.1e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.20 KPA37331.1 - 1.6e-48 164.6 0.6 6.8e-48 162.6 0.6 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KPA37331.1 - 5.6e-33 115.0 1.6 1.2e-32 114.0 0.6 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KPA37331.1 - 6.9e-29 100.1 0.1 5.1e-13 49.2 0.0 3.8 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KPA37331.1 - 1.2e-05 25.3 0.7 0.00036 20.4 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 KPA37331.1 - 2.8 8.0 8.6 17 5.5 1.7 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Ferric_reduct PF01794.19 KPA37332.1 - 1.3e-17 64.0 10.5 2.4e-17 63.2 9.7 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF420 PF04238.12 KPA37332.1 - 0.0063 16.8 13.2 0.33 11.2 1.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF420) Cu-oxidase_3 PF07732.15 KPA37334.1 - 9.1e-19 67.6 0.6 3.2e-18 65.9 0.2 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KPA37334.1 - 4.9e-16 59.2 0.0 9e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KPA37334.1 - 2.2e-09 37.2 0.1 1.4e-07 31.3 0.0 3.1 4 0 0 4 4 4 1 Multicopper oxidase PetN PF03742.14 KPA37334.1 - 0.02 14.7 2.5 0.043 13.7 2.5 1.4 1 0 0 1 1 1 0 PetN ADH_N PF08240.12 KPA37335.1 - 2.2e-30 104.7 0.8 4.3e-30 103.8 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA37335.1 - 2.5e-26 92.2 0.3 4.2e-26 91.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPA37335.1 - 3.3e-06 26.7 0.2 4.8e-06 26.2 0.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KPA37335.1 - 4.8e-06 27.7 0.1 8e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.27 KPA37335.1 - 0.041 14.4 0.1 2.3 8.8 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KPA37335.1 - 0.043 13.9 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KPA37335.1 - 0.05 12.8 0.1 0.079 12.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.17 KPA37335.1 - 0.085 13.5 0.6 0.26 11.9 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 KPA37335.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Lyase_1 PF00206.20 KPA37335.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Lyase MFS_1 PF07690.16 KPA37336.1 - 2.1e-28 99.3 31.9 2.1e-28 99.3 31.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily BTB PF00651.31 KPA37337.1 - 1.8e-06 28.1 0.3 6.6e-05 23.1 0.1 2.8 3 0 0 3 3 3 1 BTB/POZ domain L_lactis_ph-MCP PF06673.11 KPA37338.1 - 0.054 12.5 1.6 0.083 11.9 1.6 1.2 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Ferric_reduct PF01794.19 KPA37340.1 - 2.6e-23 82.5 9.6 6.4e-23 81.2 9.6 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KPA37340.1 - 2.3e-06 27.7 0.0 4.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KPA37340.1 - 0.0019 18.8 0.0 0.0035 18.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KPA37340.1 - 0.0021 18.2 1.0 0.27 11.3 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain DUF5336 PF17270.2 KPA37340.1 - 0.018 14.7 1.7 0.023 14.4 0.7 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5336) DUF420 PF04238.12 KPA37340.1 - 2.9 8.2 14.4 3.5 7.9 8.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF420) DUF3792 PF12670.7 KPA37340.1 - 6 7.1 7.2 1.5 9.0 1.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) Zn_clus PF00172.18 KPA37341.1 - 1.8e-06 27.9 9.7 3.7e-06 27.0 9.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAF-AH_p_II PF03403.13 KPA37342.1 - 7.1e-21 74.2 0.0 1.2e-10 40.5 0.0 2.1 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 KPA37342.1 - 0.0008 19.2 0.1 1.1 9.0 0.0 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family Lipase_3 PF01764.25 KPA37342.1 - 0.0013 18.6 0.0 0.0041 17.0 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Chlorophyllase2 PF12740.7 KPA37342.1 - 0.0014 17.6 0.0 0.064 12.2 0.0 2.3 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KPA37342.1 - 0.018 15.7 0.0 0.027 15.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DAO PF01266.24 KPA37343.1 - 3.4e-43 148.6 0.0 3.9e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA37343.1 - 1.1e-05 24.8 0.0 0.00086 18.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA37343.1 - 6.4e-05 23.0 0.2 0.038 14.0 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 KPA37343.1 - 0.0082 15.4 0.0 0.031 13.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KPA37343.1 - 0.043 13.0 0.0 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA37343.1 - 0.047 13.9 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPA37343.1 - 0.095 11.8 0.0 0.21 10.7 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.16 KPA37344.1 - 4.7e-05 22.5 10.2 8.7e-05 21.6 10.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N PF00107.26 KPA37345.1 - 2.9e-07 30.5 0.0 5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA37345.1 - 0.0069 16.3 0.0 0.02 14.7 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SNF2_N PF00176.23 KPA37348.1 - 2.1e-58 197.7 0.1 4.5e-58 196.6 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA37348.1 - 4e-15 56.1 0.0 1.5e-14 54.2 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KPA37348.1 - 2.5e-06 27.2 6.8 5.1e-06 26.2 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA37348.1 - 3.9e-05 23.4 8.9 8.2e-05 22.4 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KPA37348.1 - 5.8e-05 23.2 0.0 0.00017 21.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KPA37348.1 - 0.0001 22.1 8.7 0.00011 22.0 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA37348.1 - 0.0024 17.8 3.7 0.0024 17.8 3.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KPA37348.1 - 0.0027 18.0 9.6 0.0067 16.7 9.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KPA37348.1 - 0.0052 16.9 7.6 0.015 15.4 7.6 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING ERCC3_RAD25_C PF16203.5 KPA37348.1 - 0.0096 15.1 0.0 0.027 13.7 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 KPA37348.1 - 0.033 14.1 8.8 0.08 12.9 8.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 KPA37348.1 - 0.17 11.7 5.6 1.2 9.0 6.2 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Pellino PF04710.14 KPA37348.1 - 0.25 10.0 0.9 0.42 9.2 0.9 1.2 1 0 0 1 1 1 0 Pellino Baculo_IE-1 PF05290.11 KPA37348.1 - 0.33 10.9 1.7 0.82 9.6 1.7 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-MIZ PF02891.20 KPA37348.1 - 1.4 8.8 5.2 3.2 7.6 5.2 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-4CXXC_R1 PF10497.9 KPA37348.1 - 1.4 9.2 5.9 15 5.9 6.0 2.3 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Prok-RING_4 PF14447.6 KPA37348.1 - 7.2 6.6 14.7 89 3.1 0.7 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Phosphodiest PF01663.22 KPA37349.1 - 1.4e-95 321.0 1.5 2e-95 320.4 1.5 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KPA37349.1 - 0.00023 20.7 0.1 0.018 14.5 0.0 2.3 2 0 0 2 2 2 2 Sulfatase PglZ PF08665.12 KPA37349.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 PglZ domain Mem_trans PF03547.18 KPA37349.1 - 0.11 10.8 0.1 0.21 9.9 0.1 1.4 1 0 0 1 1 1 0 Membrane transport protein Zn_clus PF00172.18 KPA37350.1 - 6.7e-07 29.3 10.4 6.7e-07 29.3 10.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KPA37351.1 - 5e-32 111.3 0.0 7.4e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA37351.1 - 5.4e-22 78.6 0.0 7.7e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA37351.1 - 1.7e-07 30.9 0.0 3.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KPA37351.1 - 0.00088 19.5 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KPA37351.1 - 0.0058 16.1 0.0 0.0089 15.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_hydro_76 PF03663.14 KPA37352.1 - 8.9e-139 463.1 11.1 1.5e-138 462.4 11.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KPA37352.1 - 0.082 12.0 4.0 0.067 12.3 0.5 2.0 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 Methyltransf_31 PF13847.6 KPA37353.1 - 5.1e-11 42.6 0.0 6.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA37353.1 - 7e-11 42.7 0.0 1.2e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA37353.1 - 1.8e-09 38.1 0.0 2.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA37353.1 - 2.9e-09 37.6 0.0 4.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA37353.1 - 2.8e-06 27.3 0.0 3.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA37353.1 - 0.00032 20.3 0.0 0.001 18.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KPA37353.1 - 0.061 12.6 0.0 0.077 12.3 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KPA37353.1 - 0.076 12.9 0.0 0.18 11.8 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_20 PF12147.8 KPA37353.1 - 0.077 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase ThrE PF06738.12 KPA37354.1 - 0.036 13.4 2.0 0.06 12.7 2.0 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter OmpH PF03938.14 KPA37354.1 - 0.54 10.6 4.9 1.1 9.6 4.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.21 KPA37354.1 - 0.89 9.7 13.8 2.7 8.2 13.8 1.8 1 0 0 1 1 1 0 bZIP transcription factor UPF0242 PF06785.11 KPA37354.1 - 4.8 7.2 6.2 4.8 7.2 3.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus EptA_B_N PF08019.12 KPA37355.1 - 0.0049 16.8 4.3 0.013 15.4 1.3 2.0 2 0 0 2 2 2 1 Phosphoethanolamine transferase EptA/EptB Trp_Tyr_perm PF03222.13 KPA37355.1 - 0.013 14.6 0.6 0.019 14.0 0.6 1.2 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family GWT1 PF06423.12 KPA37355.1 - 0.12 12.5 1.0 0.17 12.0 0.8 1.3 1 1 0 1 1 1 0 GWT1 DUF4870 PF09685.10 KPA37355.1 - 0.28 11.3 6.0 0.42 10.8 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) Abhydrolase_9_N PF15420.6 KPA37355.1 - 0.33 10.9 4.2 0.16 11.9 1.2 1.8 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus SGL PF08450.12 KPA37357.1 - 0.00051 19.7 0.1 0.0008 19.1 0.1 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Cytochrom_D1 PF02239.16 KPA37357.1 - 0.11 10.9 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain SBBP PF06739.11 KPA37357.1 - 0.82 9.7 3.3 1.2 9.2 0.8 2.6 3 0 0 3 3 3 0 Beta-propeller repeat MFS_1 PF07690.16 KPA37358.1 - 2.1e-26 92.7 73.9 2.4e-24 86.0 50.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YrvL PF14184.6 KPA37358.1 - 9.2 6.4 12.7 0.27 11.3 5.4 2.3 2 0 0 2 2 2 0 Regulatory protein YrvL OPT PF03169.15 KPA37361.1 - 7.9e-63 213.1 33.9 1.3e-62 212.4 33.9 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2919 PF11143.8 KPA37361.1 - 0.19 12.1 5.3 0.84 10.0 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2919) DUF2304 PF10066.9 KPA37361.1 - 0.96 9.7 5.5 17 5.6 0.4 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) OPT PF03169.15 KPA37362.1 - 1.6e-13 50.2 0.8 1.8e-13 50.0 0.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FMO-like PF00743.19 KPA37364.1 - 1.3e-15 56.9 0.0 1.1e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPA37364.1 - 5.1e-12 45.6 0.0 1.5e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA37364.1 - 2.2e-10 40.6 0.1 1.7e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPA37364.1 - 3e-09 37.0 0.7 2.7e-08 33.9 0.1 2.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KPA37364.1 - 2.6e-06 26.8 0.1 1.7e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPA37364.1 - 4.5e-06 26.1 0.1 2.9e-05 23.5 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA37364.1 - 1.1e-05 25.2 0.0 0.047 13.3 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA37364.1 - 0.00015 22.3 1.0 4.5 7.9 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA37364.1 - 0.00042 19.6 0.2 0.001 18.4 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 KPA37364.1 - 0.0011 18.3 0.0 0.047 13.0 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KPA37364.1 - 0.0082 14.9 0.1 0.013 14.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KPA37364.1 - 0.019 14.2 0.1 0.039 13.2 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KPA37365.1 - 4.4e-55 185.8 0.0 7.6e-55 185.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPA37365.1 - 3.8e-33 114.0 0.1 4.4e-33 113.8 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KPA37365.1 - 3.5e-05 23.9 0.0 7.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KPA37365.1 - 0.00041 20.6 0.0 0.0022 18.2 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KPA37365.1 - 0.0047 16.5 0.0 0.038 13.6 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 KPA37365.1 - 0.027 15.0 0.0 0.075 13.5 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 KPA37365.1 - 0.049 12.9 0.5 0.68 9.2 0.4 2.3 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 KPA37366.1 - 5.5e-42 143.9 27.8 5.5e-42 143.9 27.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA37366.1 - 9.4e-09 34.6 25.1 2.2e-08 33.4 24.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KPA37366.1 - 3.4e-08 32.4 3.7 5.1e-08 31.8 3.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RSN1_7TM PF02714.15 KPA37368.1 - 1.9e-67 227.5 19.2 3.8e-67 226.5 19.2 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KPA37368.1 - 5.9e-38 130.1 2.0 2e-37 128.4 2.0 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KPA37368.1 - 1e-37 130.1 0.0 1.7e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter NmrA PF05368.13 KPA37369.1 - 4.2e-11 42.9 0.0 5.1e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA37369.1 - 0.0021 18.0 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF588 PF04535.12 KPA37370.1 - 0.022 14.5 1.1 0.22 11.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF588) RTA1 PF04479.13 KPA37371.1 - 3.4e-57 193.4 10.4 5.3e-57 192.8 10.4 1.2 1 0 0 1 1 1 1 RTA1 like protein CxC7 PF18866.1 KPA37371.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases RCR PF12273.8 KPA37371.1 - 0.19 12.4 0.5 0.76 10.4 0.0 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red GDP_Man_Dehyd PF16363.5 KPA37374.1 - 7.5e-60 203.1 0.0 9.7e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KPA37374.1 - 5.6e-58 196.2 0.0 6.6e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA37374.1 - 4.4e-26 91.5 0.0 5.8e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KPA37374.1 - 5.3e-17 61.8 0.0 7.1e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KPA37374.1 - 2.7e-15 56.3 0.0 1.5e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KPA37374.1 - 2.3e-12 46.7 0.0 9.2e-11 41.4 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KPA37374.1 - 4.1e-10 39.8 0.0 6.3e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KPA37374.1 - 1.5e-05 25.0 0.0 3.8e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KPA37374.1 - 1.8e-05 24.4 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KPA37374.1 - 0.00022 21.5 0.0 0.00033 20.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KPA37374.1 - 0.00037 20.0 0.0 0.0016 17.9 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 KPA37374.1 - 0.082 13.2 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain Glyco_hydro_43 PF04616.14 KPA37375.1 - 8.5e-40 136.9 8.3 9.6e-40 136.7 8.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 WTX PF09422.10 KPA37376.1 - 0.057 12.5 2.7 0.067 12.3 2.7 1.0 1 0 0 1 1 1 0 WTX protein OmpH PF03938.14 KPA37376.1 - 0.065 13.6 6.4 0.096 13.0 6.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_11 PF13086.6 KPA37376.1 - 0.21 11.3 4.0 0.23 11.2 4.0 1.1 1 0 0 1 1 1 0 AAA domain Glyco_hydro_28 PF00295.17 KPA37377.1 - 3.7e-46 157.7 4.8 5e-46 157.3 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 SWIRM-assoc_2 PF16496.5 KPA37378.1 - 0.034 13.0 0.4 0.061 12.2 0.4 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RVT_1 PF00078.27 KPA37378.1 - 0.044 13.3 0.2 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) ELM2 PF01448.24 KPA37378.1 - 0.29 11.9 1.0 7.1 7.5 0.0 3.2 3 0 0 3 3 3 0 ELM2 domain CENP-B_dimeris PF09026.10 KPA37378.1 - 0.76 10.2 7.7 1.3 9.5 6.0 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Bac_rhodopsin PF01036.18 KPA37379.1 - 7.3e-37 127.1 26.5 8.6e-37 126.9 26.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein InaF-motif PF15018.6 KPA37379.1 - 2.1 8.3 11.4 5.5 7.0 5.9 3.0 2 0 0 2 2 2 0 TRP-interacting helix PHBC_N PF12551.8 KPA37379.1 - 6.3 6.7 7.5 0.51 10.2 0.2 2.9 3 0 0 3 3 3 0 Poly-beta-hydroxybutyrate polymerase N terminal DUF3336 PF11815.8 KPA37380.1 - 2.5e-35 121.2 0.6 6.3e-35 119.9 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KPA37380.1 - 1.7e-21 77.4 0.0 3.3e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase LEA_3 PF03242.13 KPA37380.1 - 0.0086 16.8 0.8 1.2 9.9 0.0 2.8 2 0 0 2 2 2 1 Late embryogenesis abundant protein Invas_SpaK PF03519.14 KPA37380.1 - 0.085 12.9 0.7 19 5.4 0.4 2.5 2 0 0 2 2 2 0 Invasion protein B family Pyr_redox_2 PF07992.14 KPA37381.1 - 0.00027 20.3 0.1 0.00031 20.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA37381.1 - 0.00039 19.2 0.0 0.00048 18.9 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KPA37381.1 - 0.00086 18.5 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPA37381.1 - 0.0011 19.1 0.1 0.0017 18.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KPA37381.1 - 0.013 14.6 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 KPA37381.1 - 0.017 14.7 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPA37381.1 - 0.047 12.7 0.1 0.055 12.5 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KPA37381.1 - 0.053 12.8 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA37381.1 - 0.067 12.4 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KPA37381.1 - 0.088 12.1 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KPA37381.1 - 0.11 11.8 0.2 0.14 11.4 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain HET PF06985.11 KPA37382.1 - 1.1e-30 107.0 1.3 1.8e-30 106.2 1.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.7 KPA37383.1 - 5.8e-14 53.2 0.1 7.5e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA37383.1 - 0.00023 20.9 0.0 0.03 14.0 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA37383.1 - 0.045 13.0 0.1 1.8 7.7 0.1 2.5 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KPA37383.1 - 0.045 13.5 0.0 0.095 12.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KPA37383.1 - 0.061 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.12 KPA37383.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Sugar_tr PF00083.24 KPA37384.1 - 1.3e-79 268.2 23.4 1.5e-79 268.0 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA37384.1 - 3.1e-26 92.1 21.8 3.1e-26 92.1 21.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA37384.1 - 1.4e-06 27.2 18.7 0.0002 20.1 5.8 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.19 KPA37384.1 - 0.0033 16.3 8.1 0.033 13.0 0.2 2.7 2 1 1 3 3 3 2 LacY proton/sugar symporter YrhK PF14145.6 KPA37384.1 - 0.0084 16.0 0.9 0.0084 16.0 0.9 2.7 3 0 0 3 3 3 1 YrhK-like protein CutA1 PF03091.15 KPA37385.1 - 0.12 12.2 0.6 0.25 11.2 0.6 1.4 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Zn_clus PF00172.18 KPA37386.1 - 4.1e-07 30.0 13.4 7.6e-07 29.1 13.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA37386.1 - 0.3 9.9 3.8 0.13 11.1 1.4 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 KPA37390.1 - 3.2e-28 98.6 0.0 4.7e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA37390.1 - 6.2e-13 49.3 0.0 4e-12 46.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA37390.1 - 2.4e-11 44.2 0.0 2.4e-10 41.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA37390.1 - 2.4e-10 40.4 0.0 4.8e-06 26.4 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 KPA37390.1 - 2.4e-07 31.3 0.0 6.1e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KPA37390.1 - 0.00022 20.7 1.0 0.0031 17.0 0.0 2.6 2 1 1 3 3 3 1 Putative methyltransferase FtsJ PF01728.19 KPA37390.1 - 0.00039 20.6 0.0 0.001 19.3 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 KPA37390.1 - 0.0011 18.6 0.0 0.0026 17.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain GidB PF02527.15 KPA37390.1 - 0.021 14.1 0.0 0.28 10.5 0.0 2.2 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.9 KPA37390.1 - 0.038 13.7 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KPA37390.1 - 0.04 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KPA37390.1 - 0.049 13.4 0.0 0.46 10.2 0.0 2.0 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KPA37390.1 - 0.072 12.4 0.0 0.48 9.7 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family AAA_23 PF13476.6 KPA37391.1 - 1.3e-16 61.7 2.5 1.1e-14 55.4 2.5 2.5 1 1 0 1 1 1 1 AAA domain Metallophos_2 PF12850.7 KPA37391.1 - 7.5e-07 29.5 2.1 2.1e-06 28.0 2.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SMC_N PF02463.19 KPA37391.1 - 4.7e-05 22.9 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Metallophos PF00149.28 KPA37391.1 - 0.00018 22.1 0.0 0.00031 21.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA_15 PF13175.6 KPA37391.1 - 0.00046 20.0 1.3 0.00059 19.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KPA37391.1 - 0.0025 17.5 0.0 0.0066 16.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KPA37391.1 - 0.034 14.0 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KPA37391.1 - 0.16 12.5 0.5 2 8.9 0.0 2.9 3 0 0 3 3 3 0 ABC transporter V_ATPase_I PF01496.19 KPA37391.1 - 1.1 7.1 9.5 0.29 9.0 1.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PHO4 PF01384.20 KPA37392.1 - 2.5e-114 381.8 13.2 2.9e-114 381.6 13.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family zf-H2C2_2 PF13465.6 KPA37393.1 - 0.024 15.1 0.6 0.024 15.1 0.6 2.9 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.26 KPA37393.1 - 0.029 14.8 0.8 0.029 14.8 0.8 4.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type Ribosomal_L19e PF01280.20 KPA37393.1 - 0.065 13.3 0.6 0.13 12.4 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L19e zf-C2H2_4 PF13894.6 KPA37393.1 - 0.08 13.8 0.6 0.08 13.8 0.6 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger p450 PF00067.22 KPA37394.1 - 1.5e-55 188.8 0.0 4.1e-54 184.1 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 VMA21 PF09446.10 KPA37395.1 - 1.3 9.2 7.0 16 5.7 0.8 3.2 3 0 0 3 3 3 0 VMA21-like domain Fungal_trans_2 PF11951.8 KPA37396.1 - 0.00026 19.9 0.0 0.00026 19.9 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1769 PF08588.10 KPA37396.1 - 0.078 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Asparaginase PF00710.20 KPA37397.1 - 1e-18 67.6 0.0 1.5e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KPA37397.1 - 0.046 13.9 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain NPP1 PF05630.11 KPA37398.1 - 3.5e-34 118.6 0.0 4.2e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) FA_desaturase PF00487.24 KPA37399.1 - 1.6e-24 87.1 20.9 3.6e-24 86.0 20.9 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KPA37399.1 - 3.9e-06 27.1 0.0 2.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Peptidase_M48 PF01435.18 KPA37399.1 - 0.035 13.9 1.6 3.5 7.4 0.1 2.3 1 1 1 2 2 2 0 Peptidase family M48 DUF2052 PF09747.9 KPA37401.1 - 0.57 10.3 9.8 0.27 11.4 5.8 2.4 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Cu_amine_oxid PF01179.20 KPA37403.1 - 1.2e-123 413.0 5.3 1.5e-123 412.8 5.3 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KPA37403.1 - 9.7e-22 76.5 2.8 1.2e-21 76.2 1.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) HSDR_N_2 PF13588.6 KPA37406.1 - 0.026 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) TPR_12 PF13424.6 KPA37407.1 - 9.6e-08 32.2 1.0 2.7e-07 30.8 1.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KPA37407.1 - 3.7e-07 29.8 4.6 2.7e-05 23.9 0.1 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat Phe_ZIP PF08916.11 KPA37407.1 - 0.0026 18.4 2.7 0.035 14.8 2.7 2.5 1 1 0 1 1 1 1 Phenylalanine zipper TPR_19 PF14559.6 KPA37407.1 - 0.0047 17.4 1.1 0.026 15.0 1.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA37407.1 - 0.013 15.6 0.0 0.036 14.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPA37407.1 - 0.033 14.3 2.5 0.83 9.9 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPA37407.1 - 0.1 13.5 3.3 0.27 12.1 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KPA37407.1 - 0.15 12.2 1.5 0.89 9.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 KPA37408.1 - 1.6e-45 153.6 2.3 2.1e-12 47.5 0.0 6.7 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA37408.1 - 7.2e-40 134.9 9.7 7.2e-06 26.4 0.0 10.3 5 3 6 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.30 KPA37408.1 - 5.6e-31 105.6 3.3 0.001 19.4 0.0 10.9 10 2 1 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 KPA37408.1 - 3.2e-29 100.6 7.7 3.5e-05 24.0 0.1 8.5 6 2 1 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA37408.1 - 1.5e-24 83.3 10.1 0.0064 16.9 0.0 12.6 13 0 0 13 13 13 4 Ankyrin repeat PNP_UDP_1 PF01048.20 KPA37408.1 - 3.2e-14 52.8 0.1 1e-13 51.1 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KPA37408.1 - 9.9e-07 28.8 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KPA37408.1 - 0.0024 18.2 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain MFS_1 PF07690.16 KPA37409.1 - 4.7e-39 134.3 46.3 4.7e-39 134.3 46.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA37409.1 - 2.1e-08 33.5 10.2 2.1e-08 33.5 10.2 2.2 2 2 0 2 2 2 1 Sugar (and other) transporter SnoaL PF07366.12 KPA37410.1 - 7.3e-17 61.3 0.5 6.2e-14 51.9 0.1 2.7 2 1 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KPA37410.1 - 5e-07 30.3 0.0 0.0017 18.9 0.1 2.4 2 1 0 2 2 2 2 SnoaL-like domain Abhydrolase_1 PF00561.20 KPA37411.1 - 1.3e-07 31.6 0.0 2.6e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glycoamylase PF10091.9 KPA37411.1 - 0.063 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Putative glucoamylase Zn_clus PF00172.18 KPA37412.1 - 6.4e-07 29.4 8.4 1.5e-06 28.2 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA37412.1 - 7.5e-06 25.0 0.7 1.5e-05 24.0 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 KPA37414.1 - 2.2e-21 76.4 0.0 3.2e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA37414.1 - 1.7e-11 44.6 0.0 4.2e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA37414.1 - 1.1e-07 32.4 0.0 2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA37414.1 - 3.5e-07 30.1 0.0 5.6e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA37414.1 - 8.1e-06 26.5 0.0 5.7e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA37414.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain NmrA PF05368.13 KPA37415.1 - 8.7e-39 133.4 0.0 1.1e-38 133.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA37415.1 - 1.5e-25 90.2 0.0 2.8e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA37415.1 - 9.9e-08 31.7 0.0 4.7e-07 29.5 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA37415.1 - 3.9e-06 26.1 0.0 6.6e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KPA37415.1 - 0.0011 18.5 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 KPA37415.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KPA37415.1 - 0.0017 17.9 0.0 0.004 16.6 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase TrkA_N PF02254.18 KPA37415.1 - 0.014 15.6 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 KPA37415.1 - 0.062 13.2 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 KR domain RmlD_sub_bind PF04321.17 KPA37415.1 - 0.073 12.2 0.0 0.16 11.1 0.0 1.7 1 1 0 1 1 1 0 RmlD substrate binding domain MFS_1 PF07690.16 KPA37417.1 - 2.1e-44 151.9 53.9 2.1e-44 151.9 53.9 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily 2OG-FeII_Oxy_3 PF13640.6 KPA37418.1 - 5.5e-09 36.8 0.0 1.4e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_23 PF13489.6 KPA37419.1 - 8e-19 68.1 0.0 1.2e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA37419.1 - 1.6e-12 48.0 0.0 4.7e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA37419.1 - 1.3e-09 38.6 0.0 2.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA37419.1 - 2.8e-07 31.2 0.0 1.5e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA37419.1 - 2.8e-05 23.9 0.0 0.00075 19.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA37419.1 - 0.00063 19.2 0.0 0.0048 16.2 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KPA37419.1 - 0.023 14.8 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KPA37419.1 - 0.025 13.9 0.0 0.06 12.6 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_16 PF10294.9 KPA37419.1 - 0.027 14.2 0.0 0.084 12.6 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase PrmA PF06325.13 KPA37419.1 - 0.031 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KPA37419.1 - 0.055 13.0 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KPA37419.1 - 0.15 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FSA_C PF10479.9 KPA37419.1 - 1.4 7.0 4.8 2.2 6.3 4.8 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Peptidase_S10 PF00450.22 KPA37420.1 - 2.8e-94 316.9 0.1 3.5e-94 316.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase KorB PF08535.10 KPA37422.1 - 0.01 15.8 0.3 0.055 13.5 0.3 2.1 1 1 0 1 1 1 0 KorB domain DHR10 PF18595.1 KPA37422.1 - 0.015 15.3 0.8 0.015 15.3 0.8 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 KPA37422.1 - 0.057 13.5 1.3 0.11 12.5 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RPN7 PF10602.9 KPA37422.1 - 0.069 12.9 3.4 0.084 12.6 1.3 2.0 1 1 0 2 2 2 0 26S proteasome subunit RPN7 DUF2856 PF11043.8 KPA37422.1 - 0.079 13.1 1.0 5.4 7.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) HetR_C PF18460.1 KPA37422.1 - 0.13 12.2 0.9 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Sec8_exocyst PF04048.14 KPA37422.1 - 0.15 11.9 1.8 1.5 8.7 0.2 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain SYCE1 PF15233.6 KPA37422.1 - 0.16 12.0 7.1 0.58 10.2 6.1 2.2 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 FapA PF03961.13 KPA37422.1 - 0.48 9.0 2.3 0.66 8.5 2.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A BST2 PF16716.5 KPA37422.1 - 0.54 10.9 5.9 1 10.0 0.5 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Hydrolase_3 PF08282.12 KPA37423.1 - 5.5e-13 49.2 0.0 9.4e-12 45.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMM PF03332.13 KPA37423.1 - 1.3e-11 44.7 0.0 1.7e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.13 KPA37423.1 - 6.9e-07 29.0 0.0 0.022 14.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KPA37423.1 - 0.0099 16.2 0.1 0.053 13.8 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KPA37423.1 - 0.017 15.2 0.0 0.089 12.9 0.0 2.0 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 KPA37423.1 - 0.13 11.7 0.2 5.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) MS_channel PF00924.18 KPA37423.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel tRNA-synt_1c PF00749.21 KPA37424.1 - 1.2e-97 326.7 0.0 1.5e-97 326.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KPA37424.1 - 6e-38 130.4 0.0 8.7e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KPA37424.1 - 0.0066 15.8 0.7 0.018 14.4 0.8 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Zn_clus PF00172.18 KPA37425.1 - 1.9e-07 31.1 10.5 1.9e-07 31.1 10.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 KPA37426.1 - 1.2e-87 292.7 52.0 4.5e-47 160.2 21.1 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KPA37426.1 - 1.9e-37 127.0 5.3 2.3e-33 113.9 0.1 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 KPA37426.1 - 3.9e-33 114.9 0.0 1e-15 58.5 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KPA37426.1 - 1.4e-15 57.6 0.0 4.7e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KPA37426.1 - 1.3e-06 28.2 0.0 4.7e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA37426.1 - 3.7e-06 27.4 0.1 0.00061 20.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KPA37426.1 - 0.00017 21.7 0.0 0.17 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KPA37426.1 - 0.00019 21.9 0.0 0.045 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPA37426.1 - 0.00033 20.3 1.0 0.036 13.8 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KPA37426.1 - 0.00034 20.5 0.2 1.1 9.0 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPA37426.1 - 0.00042 19.8 0.0 2.7 7.4 0.0 4.2 5 1 0 5 5 5 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KPA37426.1 - 0.00046 20.1 0.1 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KPA37426.1 - 0.0015 17.7 31.5 0.1 11.7 10.8 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.6 KPA37426.1 - 0.0078 16.5 0.1 0.6 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KPA37426.1 - 0.019 14.6 0.6 0.15 11.6 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KPA37426.1 - 0.021 14.6 0.1 0.85 9.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KPA37426.1 - 0.036 14.0 0.3 1.6 8.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 KPA37426.1 - 0.037 14.5 0.2 3.7 8.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KPA37426.1 - 0.05 13.6 0.1 0.53 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KPA37426.1 - 0.084 13.4 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KPA37426.1 - 0.16 12.4 0.0 35 4.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PCRF PF03462.18 KPA37427.1 - 3.1e-42 144.6 1.3 3.9e-42 144.3 0.0 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KPA37427.1 - 2.5e-33 114.5 5.9 2.5e-33 114.5 5.9 2.0 2 0 0 2 2 2 1 RF-1 domain MFS_1 PF07690.16 KPA37427.1 - 2.3e-19 69.6 39.5 3.3e-19 69.0 39.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Tweety PF04906.13 KPA37427.1 - 0.063 11.9 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Tweety MadM PF03818.13 KPA37427.1 - 3.3 7.7 5.5 5.1 7.0 0.0 3.4 4 0 0 4 4 4 0 Malonate/sodium symporter MadM subunit GTP_cyclohydroI PF01227.22 KPA37430.1 - 7.7e-53 178.6 0.2 1.5e-39 135.3 1.1 2.1 1 1 1 2 2 2 2 GTP cyclohydrolase I QueF PF14489.6 KPA37430.1 - 0.0071 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein DUF3638 PF12340.8 KPA37430.1 - 0.054 12.8 0.2 0.083 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Sipho_tail PF05709.11 KPA37431.1 - 0.031 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein Tyrosinase PF00264.20 KPA37434.1 - 3.7e-51 174.5 1.0 5.4e-51 174.0 1.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box_2 PF09011.10 KPA37434.1 - 0.093 13.3 0.1 0.2 12.3 0.1 1.5 1 0 0 1 1 1 0 HMG-box domain Glyco_hydro_61 PF03443.14 KPA37435.1 - 6.8e-45 153.5 0.0 9.3e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SMI1_KNR4 PF09346.10 KPA37436.1 - 4.1e-10 40.1 0.5 8.6e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 KPA37436.1 - 2.7e-06 27.8 0.4 7e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 KPA37436.1 - 3.2e-06 26.9 0.0 6.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall DUF2202 PF09968.9 KPA37436.1 - 0.027 14.3 2.8 0.73 9.7 1.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein domain (DUF2202) SpoIIIAH PF12685.7 KPA37436.1 - 2.3 8.0 10.4 0.73 9.6 5.8 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF713 PF05218.14 KPA37437.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) FRG2 PF15315.6 KPA37437.1 - 0.24 11.6 14.2 0.4 10.9 14.2 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Glyco_hydro_67M PF07488.12 KPA37438.1 - 1.5e-144 481.1 0.0 2.1e-144 480.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KPA37438.1 - 8.5e-89 296.9 1.5 1.3e-88 296.3 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KPA37438.1 - 2.1e-27 95.9 0.0 3.9e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KPA37438.1 - 0.00011 23.0 0.4 0.00035 21.4 0.0 2.0 3 0 0 3 3 3 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_6 PF01341.17 KPA37439.1 - 1.1e-109 366.9 0.5 1.4e-109 366.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KPA37439.1 - 2e-10 40.4 10.8 5.7e-10 39.0 10.8 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain HA1 PF18239.1 KPA37440.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Hemagglutinin I DUF2721 PF11026.8 KPA37440.1 - 4.5 7.2 12.0 1.3 8.9 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) F-box-like PF12937.7 KPA37441.1 - 0.00073 19.4 0.1 0.0017 18.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA37441.1 - 0.0081 16.0 0.1 0.028 14.3 0.1 2.0 1 0 0 1 1 1 1 F-box domain Actin PF00022.19 KPA37442.1 - 9.2e-97 324.2 0.0 8.2e-96 321.1 0.0 1.9 1 1 0 1 1 1 1 Actin DUF5579 PF17742.1 KPA37442.1 - 0.0019 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5579) FtsA PF14450.6 KPA37442.1 - 0.028 14.8 0.0 11 6.4 0.0 2.8 2 1 0 2 2 2 0 Cell division protein FtsA MreB_Mbl PF06723.13 KPA37442.1 - 0.19 10.5 0.0 12 4.6 0.0 2.5 3 0 0 3 3 3 0 MreB/Mbl protein ADH_zinc_N_2 PF13602.6 KPA37443.1 - 1.9e-25 90.5 0.0 3.9e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KPA37443.1 - 4.2e-14 52.6 0.1 1e-13 51.4 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA37443.1 - 5.8e-08 32.6 0.6 2.3e-06 27.5 0.0 2.6 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Sugar_tr PF00083.24 KPA37444.1 - 4.5e-119 398.3 26.7 5.2e-119 398.1 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA37444.1 - 9.8e-27 93.8 46.9 5e-23 81.6 18.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA37444.1 - 7.2e-05 21.8 7.6 0.038 12.9 0.9 2.8 2 1 1 3 3 3 2 MFS_1 like family MFS_5 PF05631.14 KPA37444.1 - 0.00084 18.4 2.8 0.00084 18.4 2.8 1.7 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Patatin PF01734.22 KPA37445.1 - 3e-10 40.6 0.0 3.7e-08 33.8 0.0 2.5 1 1 0 2 2 2 2 Patatin-like phospholipase ADH_zinc_N_2 PF13602.6 KPA37446.1 - 1.3e-16 61.8 0.0 2.2e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KPA37446.1 - 1.4e-07 31.6 0.0 2.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA37446.1 - 2e-05 24.4 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 KPA37446.1 - 8.7e-05 22.9 0.0 0.00014 22.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KPA37446.1 - 0.0048 17.0 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 KPA37446.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 KPA37446.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 KPA37447.1 - 4.4e-12 45.6 0.6 7.6e-12 44.8 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37447.1 - 9.7e-11 41.6 8.7 1.7e-10 40.8 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KPA37448.1 - 2.9e-06 27.1 0.3 6.6e-06 25.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA37448.1 - 0.00052 19.8 0.2 0.0013 18.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain adh_short PF00106.25 KPA37449.1 - 1.1e-29 103.3 0.2 1.5e-29 102.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37449.1 - 2.9e-21 76.1 0.2 2.8e-20 72.9 0.2 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA37449.1 - 2.2e-05 24.5 0.1 2.8e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA37449.1 - 0.001 18.3 0.1 0.0012 18.0 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KPA37449.1 - 0.075 13.1 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sulfatase PF00884.23 KPA37450.1 - 2.3e-16 60.1 5.5 8.7e-16 58.2 5.5 1.9 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPA37450.1 - 4e-06 26.7 0.1 6e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KPA37450.1 - 0.019 13.6 0.3 0.03 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.12 KPA37450.1 - 0.03 13.4 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DnaI_N PF07319.11 KPA37452.1 - 0.088 13.5 0.1 0.2 12.4 0.1 1.5 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus Fungal_trans_2 PF11951.8 KPA37453.1 - 2.6e-32 112.1 4.1 3.7e-32 111.6 4.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S10 PF00338.22 KPA37454.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e PBP1_TM PF14812.6 KPA37456.1 - 1 9.8 5.3 2.1 8.8 5.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Putative_PNPOx PF01243.20 KPA37457.1 - 1.8e-18 66.5 0.0 2.9e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KPA37457.1 - 7.9e-11 41.9 0.5 1.5e-10 40.9 0.5 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KPA37457.1 - 7.5e-07 29.7 0.0 1.4e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KPA37457.1 - 0.0033 17.0 0.0 0.36 10.4 0.0 2.4 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase like PAN_4 PF14295.6 KPA37458.1 - 0.001 18.9 0.6 0.016 15.1 0.6 2.5 1 1 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KPA37458.1 - 0.0011 18.9 0.1 0.0025 17.7 0.1 1.6 1 0 0 1 1 1 1 PAN domain WD40 PF00400.32 KPA37459.1 - 6.9e-08 33.0 3.4 0.00028 21.6 0.1 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA37459.1 - 0.00047 20.4 0.3 0.33 11.3 0.1 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zinc_ribbon_16 PF17034.5 KPA37459.1 - 0.0044 17.2 2.4 0.0096 16.1 2.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family Ribosomal_L37ae PF01780.19 KPA37459.1 - 0.24 11.5 0.6 0.68 10.0 0.6 1.7 1 0 0 1 1 1 0 Ribosomal L37ae protein family PQQ_3 PF13570.6 KPA37459.1 - 1.1 9.9 3.0 48 4.6 0.0 3.3 2 0 0 2 2 2 0 PQQ-like domain DUF4379 PF14311.6 KPA37459.1 - 1.1 9.6 7.5 0.87 10.0 0.8 3.1 2 1 1 3 3 3 0 Probable Zinc-ribbon domain MFS_1 PF07690.16 KPA37460.1 - 3.6e-10 39.3 20.0 9e-06 24.8 6.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1195 PF06708.11 KPA37460.1 - 0.16 11.7 0.6 1.1 9.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1195) RPAP1_N PF08621.10 KPA37460.1 - 0.19 11.5 2.6 0.42 10.4 2.6 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal adh_short PF00106.25 KPA37461.1 - 5.6e-39 133.6 0.0 8.8e-39 133.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37461.1 - 2.4e-33 115.6 0.0 3.2e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA37461.1 - 8.5e-07 29.0 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA37461.1 - 0.0052 16.3 0.1 0.0087 15.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Dimer_Tnp_hAT PF05699.14 KPA37462.1 - 3.2e-19 68.5 0.1 6.1e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Rrp44_CSD1 PF17216.3 KPA37464.1 - 0.14 11.9 0.6 0.27 11.0 0.6 1.4 1 0 0 1 1 1 0 Rrp44-like cold shock domain Ank_2 PF12796.7 KPA37465.1 - 1.9e-95 313.6 0.0 2.6e-16 60.0 0.0 6.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA37465.1 - 4.6e-95 310.9 0.1 1.3e-11 44.8 0.0 10.6 4 2 7 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA37465.1 - 2e-91 288.8 0.0 1.8e-05 24.8 0.0 14.2 13 0 0 13 13 13 12 Ankyrin repeat Ank PF00023.30 KPA37465.1 - 4.8e-87 282.9 0.1 1.5e-05 25.2 0.0 13.8 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.6 KPA37465.1 - 2e-53 177.7 4.5 4.6e-07 30.0 0.0 11.8 1 1 11 12 12 12 12 Ankyrin repeats (many copies) Cthe_2159 PF14262.6 KPA37465.1 - 1.2e-05 24.8 3.6 1.1 8.6 0.0 4.7 2 2 2 5 5 5 1 Carbohydrate-binding domain-containing protein Cthe_2159 NACHT PF05729.12 KPA37465.1 - 2.7e-05 24.2 0.0 6.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPA37465.1 - 0.0029 18.0 0.0 0.0079 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain G6B PF15096.6 KPA37465.1 - 0.007 16.2 0.2 45 3.7 0.0 5.7 5 2 4 9 9 9 0 G6B family HTH_18 PF12833.7 KPA37465.1 - 0.026 14.8 0.1 25 5.3 0.0 5.8 3 1 5 9 9 9 0 Helix-turn-helix domain AAA_22 PF13401.6 KPA37465.1 - 0.049 13.9 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KPA37465.1 - 0.066 12.4 0.0 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain tRNA_deacylase PF04414.12 KPA37465.1 - 0.11 12.0 0.4 30 4.1 0.0 4.6 4 3 1 7 7 7 0 D-aminoacyl-tRNA deacylase AAA_29 PF13555.6 KPA37465.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nse4-Nse3_bdg PF15412.6 KPA37465.1 - 0.13 12.3 16.5 44 4.3 0.0 8.5 11 0 0 11 11 10 0 Binding domain of Nse4/EID3 to Nse3-MAGE Pkinase PF00069.25 KPA37467.1 - 1.5e-26 93.4 0.0 1.9e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA37467.1 - 4.4e-19 68.8 0.0 4.5e-18 65.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPA37467.1 - 0.00035 20.0 0.0 0.0005 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPA37467.1 - 0.0078 16.2 0.2 0.024 14.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KPA37467.1 - 0.0091 15.3 0.0 0.065 12.5 0.0 2.3 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KPA37467.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 RIO1 family CLN3 PF02487.17 KPA37468.1 - 6.8e-160 532.5 5.8 7.9e-160 532.3 5.8 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KPA37468.1 - 4.9e-07 29.0 23.1 1.4e-05 24.3 5.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4536 PF15055.6 KPA37468.1 - 4.2 7.7 5.4 14 6.1 1.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Cyto_heme_lyase PF01265.17 KPA37471.1 - 6.7e-44 150.6 15.1 3.2e-38 132.0 6.2 3.1 1 1 0 2 2 2 2 Cytochrome c/c1 heme lyase DUF647 PF04884.14 KPA37472.1 - 2.5e-90 302.3 2.2 3.2e-90 302.0 2.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis MDD_C PF18376.1 KPA37473.1 - 4.3e-63 212.4 0.1 5.9e-63 212.0 0.1 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KPA37473.1 - 5e-07 29.8 3.3 6e-07 29.6 1.3 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain MCU PF04678.13 KPA37474.1 - 1e-22 81.1 1.7 1e-22 81.1 1.7 2.1 2 0 0 2 2 2 1 Mitochondrial calcium uniporter Glyco_trans_4_4 PF13579.6 KPA37474.1 - 0.026 15.0 0.5 0.026 15.0 0.5 1.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Acetyltransf_8 PF13523.6 KPA37475.1 - 5.8e-41 139.6 0.0 8.1e-41 139.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Stig1 PF04885.13 KPA37476.1 - 0.0013 19.3 18.3 0.0013 19.3 18.3 9.7 6 3 4 10 10 10 5 Stigma-specific protein, Stig1 Glyco_hydro_47 PF01532.20 KPA37477.1 - 9.1e-162 539.1 0.0 1.4e-161 538.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Fungal_trans PF04082.18 KPA37477.1 - 8.8e-18 64.3 0.0 1.5e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asp PF00026.23 KPA37478.1 - 0.0058 16.1 0.1 0.023 14.1 0.0 2.0 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Amnionless PF14828.6 KPA37478.1 - 0.074 11.9 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless Fungal_trans_2 PF11951.8 KPA37479.1 - 5.9e-11 41.8 0.0 6.8e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KPA37480.1 - 8.1e-13 47.9 0.0 8.6e-13 47.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1451 PF07295.11 KPA37482.1 - 0.13 12.3 0.2 0.2 11.7 0.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-C2H2 PF00096.26 KPA37482.1 - 0.62 10.6 3.4 23 5.7 0.1 2.9 2 1 0 2 2 2 0 Zinc finger, C2H2 type DUF3292 PF11696.8 KPA37483.1 - 2.1e-272 905.3 0.0 2.3e-272 905.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Pex24p PF06398.11 KPA37483.1 - 0.0011 18.0 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin adh_short_C2 PF13561.6 KPA37484.1 - 2.7e-60 203.9 1.5 3.1e-60 203.6 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA37484.1 - 5.9e-49 166.2 4.5 7.3e-49 165.9 4.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA37484.1 - 1.4e-07 31.6 0.9 1.7e-07 31.3 0.9 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KPA37484.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3302 PF11742.8 KPA37484.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) HHH_5 PF14520.6 KPA37484.1 - 0.11 13.1 0.8 0.48 11.1 0.1 2.2 2 1 0 3 3 3 0 Helix-hairpin-helix domain HET PF06985.11 KPA37485.1 - 5.7e-27 94.9 0.0 1.2e-26 93.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_23 PF13489.6 KPA37486.1 - 9.7e-09 35.3 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA37486.1 - 1.9e-07 31.7 0.0 3.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KPA37486.1 - 0.00038 21.5 0.1 0.00092 20.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA37486.1 - 0.00055 20.6 0.0 0.0014 19.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KPA37486.1 - 0.00076 19.3 0.1 0.002 17.9 0.2 1.5 1 1 0 1 1 1 1 Lysine methyltransferase NodS PF05401.11 KPA37486.1 - 0.011 15.3 0.0 0.046 13.3 0.0 1.8 1 1 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.19 KPA37486.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KPA37486.1 - 0.017 14.9 0.1 0.04 13.7 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KPA37486.1 - 0.024 15.3 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KPA37486.1 - 0.16 11.6 0.0 0.7 9.5 0.0 2.0 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Ferric_reduct PF01794.19 KPA37489.1 - 0.011 15.8 7.0 0.011 15.8 7.0 2.4 2 1 1 3 3 3 0 Ferric reductase like transmembrane component DUF3302 PF11742.8 KPA37489.1 - 0.02 15.0 3.1 0.083 13.0 3.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) DUF1461 PF07314.11 KPA37489.1 - 0.24 11.3 5.6 0.049 13.5 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) PhoLip_ATPase_C PF16212.5 KPA37489.1 - 0.71 9.6 13.4 2 8.1 13.5 1.7 1 1 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal OST3_OST6 PF04756.13 KPA37489.1 - 1.7 7.9 5.5 2 7.7 0.0 2.5 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family Peptidase_C2 PF00648.21 KPA37490.1 - 7.9e-13 48.1 0.2 7.9e-13 48.1 0.2 2.0 2 0 0 2 2 2 1 Calpain family cysteine protease RNase_H PF00075.24 KPA37490.1 - 2.3e-12 47.3 0.2 2.3e-12 47.3 0.2 2.3 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 KPA37490.1 - 0.0075 16.1 0.0 0.37 10.6 0.0 2.6 1 1 0 1 1 1 1 Reverse transcriptase-like PSK_trans_fac PF07704.11 KPA37492.1 - 6.6 7.6 5.6 20 6.0 0.3 2.4 1 1 1 2 2 2 0 Rv0623-like transcription factor CorA PF01544.18 KPA37496.1 - 0.0009 18.6 0.1 0.0094 15.3 0.0 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein CDH-cyt PF16010.5 KPA37497.1 - 1.7e-54 184.3 0.0 3e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KPA37497.1 - 1.7e-25 90.0 0.0 3.3e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA37497.1 - 7.9e-19 68.6 0.1 1.5e-18 67.7 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_3 PF01494.19 KPA37497.1 - 2.5e-07 30.3 0.6 3.9e-07 29.6 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KPA37497.1 - 3.8e-07 29.5 1.0 1.7e-05 24.1 1.5 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA37497.1 - 1.8e-06 27.4 0.4 5.2e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA37497.1 - 2.2e-06 26.7 0.3 2.2e-06 26.7 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KPA37497.1 - 4.6e-06 26.2 1.4 7.1e-06 25.6 1.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KPA37497.1 - 7.2e-06 25.8 0.3 0.00049 19.8 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPA37497.1 - 1.9e-05 23.9 0.3 3.2e-05 23.2 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KPA37497.1 - 3.1e-05 23.2 0.1 5.3e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KPA37497.1 - 4.2e-05 23.7 0.3 0.0001 22.4 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPA37497.1 - 0.00038 19.8 0.2 0.00079 18.7 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KPA37497.1 - 0.00079 18.8 2.4 0.0033 16.7 1.6 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPA37497.1 - 0.0082 15.0 0.8 0.012 14.5 0.8 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 KPA37497.1 - 0.013 16.0 0.7 0.031 14.8 0.7 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA37497.1 - 0.091 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Zn_clus PF00172.18 KPA37498.1 - 3.7e-07 30.1 11.0 8.5e-07 29.0 11.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA37498.1 - 4.4e-05 22.5 1.2 9.8e-05 21.3 0.8 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Sulfotransfer_4 PF17784.1 KPA37499.1 - 9.9e-62 208.6 0.0 1.1e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPA37499.1 - 1e-05 26.0 0.1 0.0015 18.9 0.1 2.6 1 1 0 1 1 1 1 Sulfotransferase family Tup_N PF08581.10 KPA37500.1 - 0.1 12.9 1.1 0.19 12.0 0.2 1.8 1 1 0 2 2 2 0 Tup N-terminal VIT1 PF01988.19 KPA37500.1 - 0.22 11.4 0.2 0.3 10.9 0.2 1.2 1 0 0 1 1 1 0 VIT family Methyltransf_23 PF13489.6 KPA37501.1 - 9e-24 84.2 0.0 1.6e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA37501.1 - 3.5e-11 43.7 0.0 7.7e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA37501.1 - 6.4e-10 39.0 0.0 3.3e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA37501.1 - 6.7e-08 33.1 0.0 1.6e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA37501.1 - 1.2e-06 29.1 0.0 6.3e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KPA37501.1 - 0.00026 20.3 0.0 0.0018 17.6 0.0 2.3 2 1 0 2 2 2 1 O-methyltransferase domain CMAS PF02353.20 KPA37501.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KPA37501.1 - 0.0019 18.4 0.0 0.0028 17.8 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KPA37501.1 - 0.044 13.2 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 KPA37501.1 - 0.057 13.0 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.18 KPA37501.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Cupin_2 PF07883.11 KPA37502.1 - 1e-21 76.4 0.1 7.4e-11 41.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KPA37502.1 - 7.4e-18 64.0 0.3 2.7e-14 52.6 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KPA37502.1 - 2.7e-06 27.3 0.0 0.035 14.0 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 KPA37502.1 - 0.00039 20.6 0.0 0.00091 19.4 0.0 1.6 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_6 PF12852.7 KPA37502.1 - 0.013 15.3 0.1 0.21 11.3 0.0 2.1 1 1 1 2 2 2 0 Cupin DUF2793 PF10983.8 KPA37502.1 - 0.085 12.7 0.2 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) PBD PF00786.28 KPA37502.1 - 0.098 13.0 0.1 1.3 9.4 0.4 2.2 2 0 0 2 2 2 0 P21-Rho-binding domain Acetyltransf_1 PF00583.25 KPA37504.1 - 3.7e-09 36.8 0.0 7.4e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA37504.1 - 6.8e-05 23.2 0.2 0.00014 22.2 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA37504.1 - 0.00019 21.4 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA37504.1 - 0.026 14.6 0.0 2 8.5 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA37504.1 - 0.091 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase BTB PF00651.31 KPA37505.1 - 8.4e-06 26.0 0.0 0.00011 22.4 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Abhydrolase_6 PF12697.7 KPA37506.1 - 2.5e-06 28.3 0.4 4.1e-05 24.3 0.4 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF805 PF05656.14 KPA37507.1 - 0.002 18.5 6.4 0.002 18.5 6.4 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF805) Ank_2 PF12796.7 KPA37508.1 - 5.8e-37 126.1 0.4 1.3e-09 38.5 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA37508.1 - 3.1e-35 120.1 0.1 4.6e-07 30.3 0.0 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KPA37508.1 - 7.3e-30 102.1 1.7 0.0035 17.7 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KPA37508.1 - 5.9e-27 93.4 0.8 8.6e-08 32.3 0.0 4.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA37508.1 - 1.7e-19 67.9 0.0 0.019 15.5 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat HET PF06985.11 KPA37508.1 - 2.4e-09 37.7 3.2 6e-09 36.4 1.8 2.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) SKA2 PF16740.5 KPA37508.1 - 0.11 12.2 0.4 0.53 10.1 0.4 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3287 PF11690.8 KPA37508.1 - 0.13 12.0 5.2 3.3 7.5 0.6 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3287) Fungal_trans PF04082.18 KPA37509.1 - 1.3e-10 40.8 0.4 2e-10 40.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37509.1 - 1.7e-07 31.2 10.7 3.4e-07 30.3 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KPA37509.1 - 5.3 7.6 10.0 11 6.6 10.0 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MFS_1 PF07690.16 KPA37510.1 - 5.1e-29 101.3 46.5 2.9e-27 95.5 46.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_3 PF13302.7 KPA37510.1 - 5.3e-16 59.5 0.0 2.1e-15 57.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA37510.1 - 5.5e-10 39.5 0.0 1.7e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA37510.1 - 2.4e-06 27.9 0.0 6.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KPA37510.1 - 1.6e-05 25.1 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA37510.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KPA37510.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA37510.1 - 0.13 12.2 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 FR47-like protein Peptidase_M41 PF01434.18 KPA37511.1 - 2.2e-53 180.9 0.5 3.7e-53 180.2 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KPA37511.1 - 3.3e-43 147.3 0.0 1.1e-42 145.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA37511.1 - 5.3e-09 35.8 0.1 1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KPA37511.1 - 2.5e-06 27.5 0.0 5.5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPA37511.1 - 2.5e-05 24.7 0.3 0.00017 22.0 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA37511.1 - 4.3e-05 23.8 0.1 0.064 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KPA37511.1 - 8.2e-05 22.0 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KPA37511.1 - 0.00033 20.5 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KPA37511.1 - 0.0018 18.5 0.0 0.0049 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KPA37511.1 - 0.0086 15.8 0.1 0.026 14.2 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KPA37511.1 - 0.011 15.2 0.0 0.04 13.4 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KPA37511.1 - 0.022 14.2 0.2 0.047 13.1 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KPA37511.1 - 0.037 13.6 0.6 1.4 8.4 0.2 2.5 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 KPA37511.1 - 0.044 13.8 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KPA37511.1 - 0.046 14.0 0.2 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KPA37511.1 - 0.069 13.2 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 KPA37511.1 - 0.088 12.9 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KPA37511.1 - 0.11 13.1 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KPA37511.1 - 0.12 12.3 0.4 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KPA37511.1 - 0.16 11.2 2.1 0.91 8.8 0.4 2.3 1 1 1 2 2 2 0 Zeta toxin PhoH PF02562.16 KPA37511.1 - 0.22 11.0 0.4 0.54 9.7 0.4 1.6 1 0 0 1 1 1 0 PhoH-like protein Epimerase PF01370.21 KPA37512.1 - 5.9e-17 61.9 0.0 9.9e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA37512.1 - 6.2e-11 41.8 0.0 8.6e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPA37512.1 - 2.2e-10 40.2 0.0 4.4e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KPA37512.1 - 3.4e-08 33.3 0.0 5.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KPA37512.1 - 1.9e-07 30.5 0.0 3.6e-07 29.6 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KPA37512.1 - 5.2e-07 29.7 0.0 7.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KPA37512.1 - 0.00021 21.3 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KPA37512.1 - 0.0064 16.0 0.0 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.17 KPA37512.1 - 0.035 14.7 0.0 0.09 13.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF356 PF04009.12 KPA37512.1 - 0.082 13.2 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF356) DUF4448 PF14610.6 KPA37513.1 - 0.002 17.9 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Mucin PF01456.17 KPA37513.1 - 0.0038 17.2 2.6 0.0076 16.2 2.6 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF2207 PF09972.9 KPA37513.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CD34_antigen PF06365.12 KPA37513.1 - 0.14 11.8 0.6 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family CcmD PF04995.14 KPA37513.1 - 0.45 10.7 1.1 0.79 9.8 1.1 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) eIF3_subunit PF08597.10 KPA37514.1 - 0.051 13.5 4.7 0.13 12.1 4.7 1.7 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit ADH_zinc_N PF00107.26 KPA37515.1 - 1.7e-29 102.5 0.3 4e-29 101.2 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA37515.1 - 5.1e-24 84.2 2.0 2.1e-23 82.3 1.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPA37515.1 - 2e-06 28.9 0.1 3e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KPA37515.1 - 0.0002 20.7 0.8 0.0003 20.1 0.8 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Ank_2 PF12796.7 KPA37516.1 - 0.0015 19.1 0.0 0.0047 17.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA37516.1 - 0.0091 16.6 0.2 21 5.9 0.0 4.9 3 1 0 4 4 4 1 Ankyrin repeats (many copies) AAA_12 PF13087.6 KPA37517.1 - 1.1e-42 145.9 0.0 1.8e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPA37517.1 - 4.9e-23 82.3 0.0 1.4e-22 80.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPA37517.1 - 4e-09 37.0 0.0 1.4e-08 35.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KPA37517.1 - 2.5e-05 23.7 0.0 0.15 11.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KPA37517.1 - 0.00014 21.6 0.0 0.0014 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KPA37517.1 - 0.036 14.1 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ACOX PF01756.19 KPA37518.1 - 3e-43 147.5 0.3 6.7e-43 146.3 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KPA37518.1 - 8.2e-29 100.7 0.3 1.7e-28 99.7 0.3 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KPA37518.1 - 2.3e-12 46.9 0.0 4.5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KPA37518.1 - 5.1e-06 26.8 0.2 0.00099 19.3 0.0 2.5 2 1 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain DUF3016 PF11454.8 KPA37518.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Peptidase_M14 PF00246.24 KPA37519.1 - 0.0004 20.3 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Abhydrolase_1 PF00561.20 KPA37520.1 - 1.8e-18 67.1 0.0 1.2e-16 61.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA37520.1 - 2.6e-08 34.7 0.1 3.4e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA37520.1 - 5.9e-08 32.3 0.0 2.8e-05 23.5 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 KPA37520.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Methyltransf_11 PF08241.12 KPA37521.1 - 9.4e-12 45.4 0.0 2.5e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA37521.1 - 1.3e-11 45.0 0.1 3.7e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA37521.1 - 1.1e-07 31.8 0.0 2.3e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA37521.1 - 2.4e-06 28.2 0.0 4.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA37521.1 - 5.6e-06 26.3 0.0 9.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA37521.1 - 1.4e-05 24.6 0.0 2.7e-05 23.6 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPA37521.1 - 0.0024 17.5 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Sugar_tr PF00083.24 KPA37522.1 - 2.3e-65 221.2 22.9 1.5e-49 169.1 6.2 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPA37522.1 - 5.9e-21 74.8 30.6 1.2e-11 44.2 12.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA37523.1 - 3.4e-08 32.8 1.2 4.2e-08 32.5 1.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA37523.1 - 0.0083 15.1 0.1 0.0083 15.1 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KPA37524.1 - 9.4e-16 57.6 0.4 1.9e-15 56.6 0.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KPA37525.1 - 4.6e-51 173.8 70.1 5.7e-40 137.3 49.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA37525.1 - 4.5e-08 32.4 29.3 3.2e-06 26.3 14.6 2.3 2 0 0 2 2 2 2 MFS_1 like family Ring_hydroxyl_A PF00848.19 KPA37526.1 - 1.2e-23 84.2 0.8 1.7e-12 47.8 0.3 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KPA37526.1 - 3.7e-16 58.9 0.0 6.7e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF3884 PF13024.6 KPA37526.1 - 0.0077 15.8 0.2 0.24 11.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3884) Acetyltransf_7 PF13508.7 KPA37527.1 - 2.5e-08 34.2 0.0 1.4e-07 31.8 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA37527.1 - 1.6e-07 31.3 0.0 3.9e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA37527.1 - 2.2e-07 31.1 0.0 5e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KPA37527.1 - 0.00018 21.6 0.1 0.045 13.8 0.0 2.6 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA37527.1 - 0.0022 18.1 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KPA37527.1 - 0.0051 16.7 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein DAO PF01266.24 KPA37528.1 - 6.6e-35 121.3 1.1 7.9e-35 121.1 1.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA37528.1 - 0.00045 20.4 1.2 0.00098 19.3 0.8 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPA37528.1 - 0.0021 18.1 0.1 0.043 13.8 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPA37528.1 - 0.027 13.7 0.0 0.056 12.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA37528.1 - 0.11 13.0 0.1 0.27 11.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.8 KPA37529.1 - 2.1e-17 63.0 1.1 6.4e-17 61.4 1.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.6 KPA37530.1 - 3.6e-40 138.1 41.3 4.5e-40 137.8 41.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA37530.1 - 2e-12 46.5 33.7 2.6e-12 46.1 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease OB_Dis3 PF17849.1 KPA37531.1 - 0.086 12.9 0.2 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Dis3-like cold-shock domain 2 (CSD2) UNC-93 PF05978.16 KPA37535.1 - 4.3e-09 36.3 5.8 4.3e-09 36.3 5.8 2.6 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KPA37535.1 - 3.2e-05 23.0 27.4 0.00014 20.9 27.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily APH PF01636.23 KPA37536.1 - 7.7e-16 58.7 0.2 1.4e-15 57.9 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family HetR_C PF18460.1 KPA37536.1 - 0.00038 20.3 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 Heterocyst differentiation regulator C-terminal Hood domain DUF3632 PF12311.8 KPA37537.1 - 0.18 12.2 2.3 1.3 9.4 2.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3632) Cupin_2 PF07883.11 KPA37538.1 - 3.6e-14 52.2 0.1 5.5e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KPA37538.1 - 2.3e-07 30.4 0.1 3.1e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) 3-HAO PF06052.12 KPA37538.1 - 6.1e-06 25.9 0.0 7e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_1 PF00190.22 KPA37538.1 - 3.4e-05 23.5 0.0 4.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.7 KPA37538.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_6 PF12852.7 KPA37538.1 - 0.0034 17.1 0.0 0.0036 17.0 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KPA37538.1 - 0.0055 16.6 0.0 0.0073 16.2 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Pirin PF02678.16 KPA37538.1 - 0.0076 16.2 0.2 0.021 14.8 0.1 1.6 1 1 1 2 2 2 1 Pirin Cupin_4 PF08007.12 KPA37538.1 - 0.034 13.6 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein ARD PF03079.14 KPA37538.1 - 0.051 13.7 0.1 0.079 13.1 0.1 1.3 1 1 0 1 1 1 0 ARD/ARD' family CENP-C_C PF11699.8 KPA37538.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Mif2/CENP-C like NAD_binding_10 PF13460.6 KPA37540.1 - 5.2e-13 49.3 0.0 6e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPA37540.1 - 1e-05 25.2 0.0 1.2e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KPA37540.1 - 0.096 11.7 0.0 0.13 11.3 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.16 KPA37541.1 - 8.2e-40 136.8 38.0 9.4e-39 133.3 36.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA37541.1 - 6.6e-10 38.4 11.9 6.6e-10 38.4 11.9 2.4 2 2 1 3 3 3 1 Sugar (and other) transporter Sugar_tr PF00083.24 KPA37542.1 - 8.5e-107 357.8 21.2 1.1e-106 357.4 21.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA37542.1 - 1.3e-25 90.1 29.0 1.3e-25 90.1 29.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KPA37542.1 - 1.9e-19 70.1 0.4 1e-09 38.1 0.2 3.0 2 1 0 2 2 2 2 FAD binding domain MFS_2 PF13347.6 KPA37542.1 - 7.3e-08 31.4 20.5 5.4e-06 25.2 2.0 3.9 2 2 1 3 3 3 2 MFS/sugar transport protein SE PF08491.10 KPA37542.1 - 1.3e-06 27.7 0.0 6.4e-05 22.1 0.0 2.5 3 0 0 3 3 3 1 Squalene epoxidase NAD_binding_8 PF13450.6 KPA37542.1 - 0.0006 20.0 0.2 0.0006 20.0 0.2 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPA37542.1 - 0.00064 18.9 0.0 0.071 12.1 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KPA37542.1 - 0.00074 19.2 0.2 0.0012 18.5 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 KPA37542.1 - 0.0011 18.7 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KPA37542.1 - 0.0074 15.6 0.0 0.0074 15.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA37542.1 - 0.013 16.0 0.1 0.04 14.5 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA37542.1 - 0.014 14.2 0.0 0.026 13.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KPA37542.1 - 0.075 12.1 0.2 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain AIP3 PF03915.13 KPA37543.1 - 3.4e-155 517.2 8.6 5.3e-155 516.5 8.6 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Phage_GP20 PF06810.11 KPA37543.1 - 0.0077 16.0 1.6 3.9 7.3 0.0 3.2 1 1 1 2 2 2 2 Phage minor structural protein GP20 DUF1664 PF07889.12 KPA37543.1 - 0.01 15.8 3.2 0.4 10.7 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FliL PF03748.14 KPA37543.1 - 0.05 14.2 0.6 0.34 11.5 0.1 2.7 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL MIP-T3_C PF17749.1 KPA37543.1 - 0.1 12.5 6.7 0.074 13.0 0.4 3.2 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Med11 PF10280.9 KPA37543.1 - 0.32 11.5 5.7 1.9 8.9 0.1 3.5 3 1 0 3 3 3 0 Mediator complex protein Baculo_PEP_C PF04513.12 KPA37543.1 - 4.3 7.4 7.3 32 4.5 0.5 3.8 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 KPA37543.1 - 4.5 7.3 9.3 3.7 7.6 1.4 3.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 KPA37544.1 - 0.093 12.4 25.7 0.12 12.1 15.4 2.7 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease HrpB7 PF09486.10 KPA37544.1 - 0.21 12.0 12.2 0.07 13.5 9.3 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Csm1_N PF18504.1 KPA37544.1 - 0.36 11.2 0.0 0.36 11.2 0.0 4.0 2 2 1 3 3 3 0 Csm1 N-terminal domain DUF812 PF05667.11 KPA37544.1 - 4 6.2 18.5 0.24 10.2 13.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) AKAP7_NLS PF10469.9 KPA37545.1 - 1.9e-33 116.1 0.0 2.1e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 KPA37545.1 - 0.1 12.8 0.1 11 6.4 0.0 3.1 2 1 0 2 2 2 0 LigT like Phosphoesterase PAP_assoc PF03828.19 KPA37546.1 - 1.4e-17 63.7 0.2 4.1e-17 62.1 0.2 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KPA37546.1 - 2.7e-06 27.6 0.0 5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KPA37546.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase ADH_zinc_N PF00107.26 KPA37547.1 - 0.025 14.6 0.1 0.049 13.6 0.1 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase YcbB PF08664.10 KPA37548.1 - 0.0016 18.5 0.5 0.0044 17.1 0.4 1.7 2 0 0 2 2 2 1 YcbB domain Period_C PF12114.8 KPA37548.1 - 0.48 10.0 2.7 1 8.9 2.7 1.6 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF1929 PF09118.11 KPA37549.1 - 2.5e-26 91.8 0.4 5.1e-26 90.8 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KPA37549.1 - 9.1e-14 51.2 1.5 0.0027 17.9 0.1 4.5 4 0 0 4 4 4 3 Kelch motif F5_F8_type_C PF00754.25 KPA37549.1 - 1.3e-10 41.5 1.5 0.00012 22.1 0.0 3.0 1 1 1 2 2 2 2 F5/8 type C domain Kelch_1 PF01344.25 KPA37549.1 - 2e-07 30.5 3.9 6.2e-06 25.7 0.1 3.5 3 1 0 3 3 3 1 Kelch motif Glyoxal_oxid_N PF07250.11 KPA37549.1 - 3.3e-06 26.5 0.1 0.011 14.9 0.1 2.6 3 0 0 3 3 3 2 Glyoxal oxidase N-terminus Kelch_4 PF13418.6 KPA37549.1 - 4.5e-06 26.6 7.1 0.001 19.0 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KPA37549.1 - 2e-05 24.4 0.8 0.0023 17.8 0.1 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 KPA37549.1 - 0.01 15.8 0.4 0.7 10.0 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Carb_anhydrase PF00194.21 KPA37550.1 - 5.6e-31 108.0 0.9 5.5e-30 104.8 0.9 2.0 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Cullin PF00888.22 KPA37551.1 - 2.4e-20 72.7 0.2 2.7e-20 72.6 0.2 1.0 1 0 0 1 1 1 1 Cullin family adh_short PF00106.25 KPA37552.1 - 1.2e-29 103.2 0.0 1.5e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37552.1 - 5.6e-22 78.4 0.0 6.9e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA37552.1 - 1.2e-08 35.0 0.0 1.7e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPA37552.1 - 0.00023 21.1 0.1 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA37552.1 - 0.025 14.0 0.0 0.045 13.2 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4295 PF14128.6 KPA37552.1 - 0.055 13.3 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) NUDIX PF00293.28 KPA37553.1 - 1.3e-08 34.9 0.0 2.3e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain adh_short PF00106.25 KPA37554.1 - 1.4e-34 119.2 0.0 1.8e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37554.1 - 1.1e-18 67.7 0.0 1.4e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA37554.1 - 2e-06 27.9 0.1 3.6e-06 27.0 0.1 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPA37554.1 - 0.00016 21.6 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPA37554.1 - 0.00074 19.8 0.0 0.00098 19.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPA37554.1 - 0.00095 18.7 0.1 0.0022 17.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KPA37554.1 - 0.009 16.1 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KPA37554.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KPA37554.1 - 0.02 15.5 0.1 0.038 14.6 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KPA37554.1 - 0.029 14.6 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1295 PF06966.12 KPA37555.1 - 1.5e-30 106.5 0.0 2.1e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KPA37555.1 - 0.0043 17.4 0.0 0.0088 16.4 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KPA37555.1 - 0.0046 16.9 0.0 0.0091 16.0 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase NnrU PF07298.11 KPA37555.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 NnrU protein PEMT PF04191.13 KPA37555.1 - 0.083 13.3 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KPA37555.1 - 0.094 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Sugar_tr PF00083.24 KPA37556.1 - 3.5e-70 237.1 20.4 4.1e-70 236.9 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA37556.1 - 3.4e-10 39.4 38.0 2e-09 36.8 30.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA37556.1 - 0.00041 19.0 16.2 0.032 12.8 3.7 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KPA37556.1 - 0.00054 18.9 4.1 0.00054 18.9 4.1 2.2 2 0 0 2 2 2 1 MFS_1 like family bZIP_1 PF00170.21 KPA37557.1 - 1.1e-05 25.4 4.0 1.1e-05 25.4 4.0 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KPA37557.1 - 2.2e-05 24.4 5.7 4.6e-05 23.4 5.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KPA37557.1 - 0.03 14.8 4.0 0.056 14.0 4.0 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DNA_pol_A_exo1 PF01612.20 KPA37559.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 3'-5' exonuclease HNH_2 PF13391.6 KPA37560.1 - 4.7e-13 49.1 0.2 1.5e-12 47.5 0.1 2.0 2 0 0 2 2 2 1 HNH endonuclease SRP54_N PF02881.19 KPA37561.1 - 0.048 13.9 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain DUF1939 PF09154.10 KPA37561.1 - 0.15 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Exo_endo_phos PF03372.23 KPA37563.1 - 2.6e-08 33.7 1.4 5.4e-08 32.6 1.4 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Microvir_lysis PF04517.12 KPA37563.1 - 0.23 11.4 0.9 1.2 9.1 0.3 2.2 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus Serpentine_r_xa PF03383.15 KPA37564.1 - 0.088 12.8 1.4 0.14 12.1 1.4 1.3 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa 7tm_1 PF00001.21 KPA37564.1 - 1.8 7.8 6.2 3 7.1 6.1 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Peptidase_S58 PF03576.14 KPA37565.1 - 1e-112 376.5 0.9 1.2e-112 376.3 0.9 1.0 1 0 0 1 1 1 1 Peptidase family S58 MFS_1 PF07690.16 KPA37566.1 - 1.4e-34 119.6 19.2 1e-19 70.7 8.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA37566.1 - 0.00045 19.2 6.1 0.00045 19.2 6.1 2.7 1 1 2 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KPA37566.1 - 0.00064 18.1 11.2 0.24 9.6 1.4 3.6 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KPA37566.1 - 0.19 10.6 16.5 0.014 14.2 7.7 2.2 1 1 1 2 2 2 0 MFS_1 like family Metallophos PF00149.28 KPA37567.1 - 2.7e-14 54.2 3.1 4.5e-14 53.4 3.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HAD_2 PF13419.6 KPA37568.1 - 1.9e-12 47.6 0.0 1.1e-11 45.2 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA37568.1 - 3.3e-10 40.6 0.0 2.4e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA37568.1 - 0.00015 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Erf4 PF10256.9 KPA37569.1 - 0.00034 20.7 0.0 0.0036 17.4 0.0 2.4 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF1943 PF09172.11 KPA37569.1 - 8.5 5.5 7.5 12 5.0 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) ANAPC_CDC26 PF10471.9 KPA37569.1 - 9.2 7.2 12.6 7.6 7.4 1.6 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Zn_clus PF00172.18 KPA37570.1 - 9.8e-10 38.4 11.1 1.8e-09 37.6 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MHC_I PF00129.18 KPA37571.1 - 0.022 14.3 0.0 0.057 13.0 0.0 1.7 1 1 1 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 F-box PF00646.33 KPA37572.1 - 0.049 13.5 0.0 0.049 13.5 0.0 2.1 3 0 0 3 3 3 0 F-box domain HTH_Tnp_Tc3_2 PF01498.18 KPA37573.1 - 2.8e-12 46.7 0.0 3.9e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.6 KPA37573.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix MTA_R1 PF17226.2 KPA37573.1 - 0.053 13.7 0.1 0.081 13.1 0.1 1.2 1 0 0 1 1 1 0 MTA R1 domain DUF4224 PF13986.6 KPA37573.1 - 0.08 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) F-box_4 PF15966.5 KPA37574.1 - 0.0022 17.9 0.1 0.0048 16.8 0.1 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 KPA37574.1 - 0.0089 15.9 0.2 0.023 14.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain p450 PF00067.22 KPA37575.1 - 2.8e-69 234.0 0.0 3.5e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PTR2 PF00854.21 KPA37576.1 - 7.5e-72 242.3 9.8 1.2e-71 241.7 9.8 1.3 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KPA37576.1 - 4.1e-09 35.8 14.1 7.6e-08 31.7 14.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Holin_SPP1 PF04688.13 KPA37576.1 - 0.18 12.0 2.6 1.2 9.4 0.3 2.6 2 0 0 2 2 2 0 SPP1 phage holin CFEM PF05730.11 KPA37577.1 - 0.00012 22.1 11.3 0.00027 20.9 11.3 1.6 1 0 0 1 1 1 1 CFEM domain Mucin PF01456.17 KPA37577.1 - 0.038 14.0 15.6 0.029 14.4 14.0 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF1340 PF07067.11 KPA37577.1 - 0.11 11.9 0.6 0.15 11.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) CoA_transf_3 PF02515.17 KPA37579.1 - 1.6e-50 172.3 0.0 1e-48 166.3 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III Transferase PF02458.15 KPA37580.1 - 0.0019 16.9 0.0 0.72 8.4 0.0 3.1 4 0 0 4 4 4 3 Transferase family HNH_2 PF13391.6 KPA37582.1 - 0.0092 16.1 0.0 0.025 14.7 0.0 1.9 1 0 0 1 1 1 1 HNH endonuclease F-box-like PF12937.7 KPA37583.1 - 0.0002 21.2 0.4 0.0024 17.7 0.2 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KPA37583.1 - 0.09 12.7 1.1 0.24 11.3 0.4 2.1 2 0 0 2 2 2 0 F-box domain LRR_6 PF13516.6 KPA37583.1 - 1.6 9.0 7.1 48 4.4 1.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_2 PF07723.13 KPA37583.1 - 2.5 8.9 5.0 8.7 7.2 0.1 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat Sugar_tr PF00083.24 KPA37585.1 - 7.4e-83 278.9 16.5 8.6e-83 278.7 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA37585.1 - 1.3e-19 70.4 31.1 5.2e-16 58.5 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA37585.1 - 2.1e-06 26.6 20.5 0.00035 19.3 3.2 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_4 PF06779.14 KPA37585.1 - 0.00067 19.1 2.2 0.00067 19.1 2.2 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ADH_N PF08240.12 KPA37586.1 - 1.7e-05 24.7 0.0 4.2e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain His_Phos_1 PF00300.22 KPA37587.1 - 4.3e-08 33.1 0.0 6.9e-07 29.2 0.0 2.7 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) Candida_ALS PF05792.13 KPA37588.1 - 3e-08 34.1 39.0 3.2e-07 30.8 6.3 52.9 53 2 1 54 54 54 26 Candida agglutinin-like (ALS) Peptidase_A6 PF01829.16 KPA37589.1 - 0.056 12.8 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase A6 family JmjC PF02373.22 KPA37590.1 - 0.00026 21.4 0.2 0.0065 16.9 0.0 2.9 2 1 0 3 3 3 1 JmjC domain, hydroxylase DUF1247 PF06851.11 KPA37593.1 - 0.22 11.4 1.2 14 5.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1247) ELM2 PF01448.24 KPA37593.1 - 1.8 9.4 6.1 25 5.7 0.8 3.6 3 0 0 3 3 3 0 ELM2 domain Cyclin_N PF00134.23 KPA37595.1 - 9.8e-34 115.8 0.1 1.8e-33 115.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KPA37595.1 - 3.2e-08 33.7 0.1 2e-07 31.1 0.1 2.4 1 1 0 1 1 1 1 Cyclin, C-terminal domain Y_phosphatase3 PF13350.6 KPA37598.1 - 2.8e-50 171.5 0.0 3.2e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KPA37598.1 - 0.00037 20.1 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KPA37598.1 - 0.0026 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KPA37598.1 - 0.062 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Ribosomal_L22e PF01776.17 KPA37599.1 - 1.2e-45 154.4 2.2 1.5e-45 154.1 2.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Dimer_Tnp_Tn5 PF02281.16 KPA37599.1 - 0.1 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain Mito_carr PF00153.27 KPA37600.1 - 4.6e-33 113.0 0.0 1.9e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3824 PF12868.7 KPA37601.1 - 0.00021 22.0 4.6 0.00021 22.0 4.6 9.5 7 3 2 9 9 9 2 Domain of unknwon function (DUF3824) RCR PF12273.8 KPA37602.1 - 0.00032 21.3 4.5 0.0011 19.7 4.5 1.8 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Herpes_gE PF02480.16 KPA37602.1 - 0.048 12.4 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Tfb5 PF06331.12 KPA37603.1 - 3.9e-26 90.8 0.3 4.2e-26 90.7 0.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 ECH_1 PF00378.20 KPA37604.1 - 3.3e-43 147.8 0.5 6.3e-43 146.9 0.5 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA37604.1 - 3.6e-33 115.5 0.1 7e-29 101.4 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Glyco_hydro_16 PF00722.21 KPA37605.1 - 9.8e-14 51.2 0.3 1.5e-13 50.6 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.18 KPA37606.1 - 2.1e-15 56.5 1.7 3.6e-15 55.7 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KPA37606.1 - 1.1e-07 31.9 13.4 1.1e-05 25.6 5.8 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KPA37606.1 - 0.00076 19.8 14.6 0.04 14.4 5.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KPA37606.1 - 0.018 15.7 0.6 2.1 9.1 0.1 2.7 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 KPA37606.1 - 0.22 12.4 19.5 0.27 12.2 4.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA37606.1 - 0.35 11.2 5.7 1.4 9.3 3.7 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPA37606.1 - 0.91 10.0 2.9 14 6.3 2.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KPA37606.1 - 1.5 9.0 4.1 4.1 7.6 4.1 1.8 1 0 0 1 1 1 0 Zinc ribbon domain RasGEF PF00617.19 KPA37607.1 - 5.9e-58 196.0 0.1 1.1e-57 195.1 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KPA37607.1 - 7.4e-28 96.9 0.9 1.9e-27 95.6 0.9 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KPA37607.1 - 5.5e-13 48.3 0.0 1.2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPA37607.1 - 3.5e-12 46.0 0.1 7.5e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPA37607.1 - 7.6e-11 41.5 0.1 1.6e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KPA37607.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 WW domain Ser_hydrolase PF06821.13 KPA37607.1 - 0.16 11.8 0.3 0.29 11.0 0.3 1.3 1 0 0 1 1 1 0 Serine hydrolase ADH_N_2 PF16884.5 KPA37609.1 - 1.9e-26 92.1 0.0 4.7e-26 90.8 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KPA37609.1 - 7.6e-18 64.7 0.2 1.2e-17 64.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA37609.1 - 2.7e-10 41.4 0.1 5.8e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sugar_tr PF00083.24 KPA37610.1 - 3.1e-93 313.1 21.2 3.7e-93 312.9 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA37610.1 - 9.1e-25 87.3 37.1 7.7e-20 71.1 17.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA37610.1 - 3.2e-05 22.6 0.6 3.2e-05 22.6 0.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 KPA37610.1 - 0.0026 18.2 0.9 0.012 16.2 0.9 2.1 1 0 0 1 1 1 1 Phage holin family 2 Pollen_allerg_1 PF01357.21 KPA37611.1 - 2.4e-05 24.3 0.7 7.2e-05 22.7 0.7 1.8 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.18 KPA37611.1 - 0.0031 17.7 0.1 0.015 15.5 0.1 2.4 1 1 0 1 1 1 1 Lytic transglycolase Ecm33 PF12454.8 KPA37611.1 - 0.048 13.8 1.9 0.097 12.8 0.2 2.4 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein Cerato-platanin PF07249.12 KPA37611.1 - 0.11 12.7 2.3 0.21 11.8 0.5 2.2 2 1 0 2 2 2 0 Cerato-platanin Mo-co_dimer PF03404.16 KPA37611.1 - 0.13 12.3 0.7 0.68 10.0 0.7 2.1 1 1 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Med3 PF11593.8 KPA37611.1 - 0.15 11.2 11.3 0.19 10.9 11.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RTA1 PF04479.13 KPA37613.1 - 3.5e-65 219.5 10.3 3.5e-65 219.5 10.3 1.5 2 0 0 2 2 2 1 RTA1 like protein adh_short PF00106.25 KPA37614.1 - 3.5e-16 59.2 0.0 5.3e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37614.1 - 1.6e-07 31.1 0.0 2.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KPA37614.1 - 0.091 12.6 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H-binding KR PF08659.10 KPA37614.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF669 PF05037.13 KPA37614.1 - 0.18 11.9 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF669) AlaDh_PNT_N PF05222.15 KPA37616.1 - 1.4e-20 74.0 0.0 2.4e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KPA37616.1 - 0.00016 21.0 0.0 0.00028 20.3 0.0 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KPA37617.1 - 2.4e-13 50.1 0.0 2.1e-10 40.5 0.0 2.1 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 KPA37617.1 - 0.0046 17.1 0.0 0.0062 16.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KPA37617.1 - 0.009 16.3 0.0 0.021 15.1 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain Methyltransf_25 PF13649.6 KPA37617.1 - 0.044 14.5 0.0 0.069 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain F420_oxidored PF03807.17 KPA37617.1 - 0.044 14.4 0.0 0.091 13.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_31 PF13847.6 KPA37617.1 - 0.048 13.4 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 KPA37617.1 - 0.054 13.4 0.0 0.089 12.7 0.0 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 KPA37617.1 - 0.2 12.4 0.0 0.4 11.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Chitin_synth_2 PF03142.15 KPA37618.1 - 8.4e-29 100.6 0.0 3.7e-24 85.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 KPA37618.1 - 3e-09 37.1 0.1 9.6e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KPA37618.1 - 2.3e-06 27.6 0.9 4.4e-06 26.7 0.9 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KPA37618.1 - 3.1e-05 23.9 0.0 0.082 12.7 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 2 Ribosomal_60s PF00428.19 KPA37618.1 - 0.033 14.8 1.3 0.08 13.5 1.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4728 PF15860.5 KPA37618.1 - 0.81 10.4 4.8 0.81 10.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) Pectate_lyase_3 PF12708.7 KPA37619.1 - 3.1e-08 33.7 0.8 1.1e-07 32.0 0.3 2.2 1 1 0 2 2 2 1 Pectate lyase superfamily protein Sugar_tr PF00083.24 KPA37620.1 - 8.6e-83 278.7 18.5 1.2e-82 278.2 18.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA37620.1 - 2.9e-26 92.2 25.9 1e-25 90.5 25.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA37620.1 - 4.7e-05 22.0 1.1 4.7e-05 22.0 1.1 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Herpes_UL49_5 PF05702.11 KPA37623.1 - 0.1 12.7 0.2 0.23 11.6 0.2 1.6 1 1 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Cupin_3 PF05899.12 KPA37624.1 - 1e-07 31.5 0.3 1.8e-07 30.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 KPA37624.1 - 0.00021 21.1 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.11 KPA37624.1 - 0.021 14.5 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 Cupin domain DUF4437 PF14499.6 KPA37624.1 - 0.059 12.5 0.2 0.11 11.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4437) HET PF06985.11 KPA37626.1 - 3.7e-26 92.2 0.1 1.1e-25 90.7 0.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SDH_alpha PF03313.15 KPA37627.1 - 1.6e-97 326.2 0.1 2.2e-97 325.8 0.1 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 KPA37627.1 - 7.8e-54 182.3 0.0 1.8e-53 181.1 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain Dioxygenase_C PF00775.21 KPA37628.1 - 5.8e-48 162.7 0.0 7.7e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KPA37628.1 - 7.3e-30 102.7 0.1 1.1e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KPA37628.1 - 1.7e-06 28.2 0.0 4.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain bMG3 PF11974.8 KPA37628.1 - 0.029 14.4 0.0 0.09 12.8 0.0 1.9 1 1 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain CarbopepD_reg_2 PF13715.6 KPA37628.1 - 0.031 14.3 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 0 CarboxypepD_reg-like domain CoA_transf_3 PF02515.17 KPA37629.1 - 3.2e-40 138.4 0.0 3e-37 128.6 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Spidroin_N PF16763.5 KPA37629.1 - 0.058 13.4 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term Hydrolase_4 PF12146.8 KPA37630.1 - 4.9e-19 68.5 0.1 2.8e-18 66.1 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA37630.1 - 7.2e-16 59.5 0.0 1.4e-15 58.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA37630.1 - 3.5e-12 46.5 0.1 4.5e-11 42.9 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Fungal_trans PF04082.18 KPA37630.1 - 1.7e-10 40.4 0.0 2.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37630.1 - 2.3e-07 30.8 12.7 4.5e-07 29.9 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chlorophyllase2 PF12740.7 KPA37630.1 - 2.2e-05 23.5 0.0 3.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 KPA37630.1 - 0.00043 19.9 0.0 0.12 11.9 0.0 3.1 2 2 1 3 3 3 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 KPA37630.1 - 0.0012 17.4 0.3 0.0076 14.8 0.3 2.0 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.16 KPA37630.1 - 0.0013 18.5 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KPA37630.1 - 0.0095 15.4 0.0 0.7 9.3 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ndr PF03096.14 KPA37630.1 - 0.016 13.9 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 Ndr family Chlorophyllase PF07224.11 KPA37630.1 - 0.059 12.4 0.1 0.098 11.7 0.1 1.3 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_5 PF12695.7 KPA37630.1 - 0.17 11.6 0.2 0.72 9.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family FucT_N PF18025.1 KPA37631.1 - 0.13 12.7 0.4 0.41 11.1 0.1 1.9 2 0 0 2 2 2 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain AA_permease_2 PF13520.6 KPA37632.1 - 8.6e-46 156.6 51.7 1e-45 156.3 51.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA37632.1 - 1.8e-21 76.3 34.9 1.8e-21 76.3 34.9 1.8 2 0 0 2 2 2 1 Amino acid permease Cupin_2 PF07883.11 KPA37633.1 - 0.00048 19.8 0.1 0.00083 19.0 0.1 1.3 1 0 0 1 1 1 1 Cupin domain FdtA PF05523.11 KPA37633.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal CN_hydrolase PF00795.22 KPA37634.1 - 2e-31 109.3 0.0 4.8e-31 108.0 0.0 1.7 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase EthD PF07110.11 KPA37636.1 - 1.9e-20 73.8 1.5 2.9e-20 73.2 1.5 1.3 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KPA37636.1 - 7.2e-06 26.4 0.2 1.1e-05 25.8 0.2 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase UvrB PF12344.8 KPA37636.1 - 0.14 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Ultra-violet resistance protein B Fungal_trans PF04082.18 KPA37639.1 - 4.7e-35 120.9 0.2 9.6e-35 119.9 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain LIP PF03583.14 KPA37640.1 - 5.9e-82 275.2 0.1 7.9e-82 274.8 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Esterase_phd PF10503.9 KPA37641.1 - 3.9e-21 75.6 0.1 5.3e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KPA37641.1 - 3.1e-06 26.8 0.2 5.6e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KPA37641.1 - 0.00013 21.9 0.0 0.0023 17.7 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 KPA37641.1 - 0.014 15.4 0.1 0.024 14.6 0.1 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KPA37641.1 - 0.015 15.2 0.1 0.074 12.9 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KPA37641.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Gmad2 PF10648.9 KPA37641.1 - 0.13 12.5 0.0 0.56 10.5 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination Cu-oxidase_3 PF07732.15 KPA37642.1 - 4e-43 146.2 5.5 2.2e-40 137.4 2.2 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KPA37642.1 - 2.1e-36 124.7 8.6 1.4e-35 122.0 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KPA37642.1 - 5.2e-28 98.2 0.0 3e-27 95.7 0.0 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cyt-b5 PF00173.28 KPA37643.1 - 3.5e-15 55.9 0.0 8.1e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.18 KPA37643.1 - 1.5e-14 53.7 0.0 1.3e-10 40.7 0.0 2.7 3 0 0 3 3 3 2 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.20 KPA37643.1 - 1.2e-09 38.1 0.0 6.1e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KPA37643.1 - 1.1e-06 29.2 0.0 2.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Phasin_2 PF09361.10 KPA37643.1 - 0.46 10.8 1.9 4.3 7.6 0.0 2.7 2 0 0 2 2 2 0 Phasin protein PS_Dcarbxylase PF02666.15 KPA37644.1 - 1.3e-34 119.5 0.0 1.8e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 KPA37644.1 - 3.8e-34 117.7 0.5 7.1e-34 116.8 0.5 1.5 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.6 KPA37644.1 - 0.0016 18.3 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 KPA37644.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 1 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Tyrosinase PF00264.20 KPA37645.1 - 5.2e-50 170.8 1.0 1e-49 169.9 1.0 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase F-box-like PF12937.7 KPA37645.1 - 2e-05 24.4 0.0 4.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA37645.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 F-box domain Pectate_lyase_3 PF12708.7 KPA37646.1 - 1e-13 51.7 0.4 2.4e-13 50.4 0.4 1.7 1 0 0 1 1 1 1 Pectate lyase superfamily protein LysM PF01476.20 KPA37646.1 - 0.0066 16.5 0.0 0.02 15.0 0.0 1.9 1 0 0 1 1 1 1 LysM domain End_N_terminal PF12218.8 KPA37646.1 - 0.018 14.7 0.1 0.039 13.6 0.1 1.5 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase DUF4160 PF13711.6 KPA37647.1 - 0.016 15.5 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Ank_2 PF12796.7 KPA37649.1 - 5.7e-22 78.1 0.0 8.1e-12 45.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA37649.1 - 2.9e-17 61.0 0.0 0.00042 20.5 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KPA37649.1 - 2.6e-16 59.7 0.0 5.1e-09 36.5 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KPA37649.1 - 1.3e-15 57.1 0.0 0.00029 21.2 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KPA37649.1 - 4e-11 42.9 0.0 2.5e-05 24.5 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) NACHT PF05729.12 KPA37649.1 - 9.6e-10 38.6 1.7 2e-06 27.8 0.1 3.1 3 0 0 3 3 3 2 NACHT domain Abhydrolase_6 PF12697.7 KPA37649.1 - 2.4e-06 28.3 0.0 1.8e-05 25.5 0.0 2.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.6 KPA37649.1 - 6e-05 23.5 0.0 0.0002 21.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.14 KPA37649.1 - 0.012 15.1 0.0 0.095 12.2 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) AAA_22 PF13401.6 KPA37649.1 - 0.014 15.6 0.0 0.072 13.4 0.0 2.3 2 0 0 2 2 1 0 AAA domain VWA_3_C PF18571.1 KPA37649.1 - 0.048 13.5 3.3 27 4.7 0.0 3.9 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain AAA_29 PF13555.6 KPA37649.1 - 0.088 12.6 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 KPA37649.1 - 0.12 12.3 0.1 2.7 7.9 0.0 2.5 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 KAP_NTPase PF07693.14 KPA37649.1 - 0.15 11.3 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain APCDDC PF14921.6 KPA37650.1 - 0.21 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 Ank_2 PF12796.7 KPA37651.1 - 1.9e-59 198.2 28.8 3.7e-16 59.5 2.8 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA37651.1 - 1.5e-50 168.9 21.7 7.9e-11 42.3 0.1 7.4 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KPA37651.1 - 4.5e-39 131.2 28.9 0.00027 21.3 0.2 9.1 8 1 1 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 KPA37651.1 - 2.8e-35 116.3 13.8 0.0012 19.1 0.1 8.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KPA37651.1 - 2.4e-30 104.2 15.5 3.9e-05 23.9 0.2 7.8 2 1 6 8 8 8 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 KPA37651.1 - 9.8e-06 25.4 0.0 1.4 8.9 0.0 3.9 2 2 2 4 4 4 3 Domain of unknown function (DUF3447) DUF1843 PF08898.10 KPA37651.1 - 3.3e-05 24.3 10.2 4.2 8.0 0.2 5.9 4 2 2 6 6 6 1 Domain of unknown function (DUF1843) DUF3533 PF12051.8 KPA37652.1 - 4.7e-56 190.3 0.1 6e-56 190.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF2684 PF10885.8 KPA37652.1 - 0.0012 18.9 0.3 0.0073 16.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2684) Abhydrolase_6 PF12697.7 KPA37654.1 - 1.7e-15 58.2 1.1 2e-15 58.0 1.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA37654.1 - 0.00025 20.4 0.1 0.0004 19.7 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KPA37654.1 - 0.002 18.3 0.0 0.0029 17.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF900 PF05990.12 KPA37654.1 - 0.047 13.2 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) FAD_binding_3 PF01494.19 KPA37655.1 - 5.6e-17 62.0 0.1 7.1e-16 58.4 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA37655.1 - 1.3e-07 31.5 0.5 5e-07 29.6 0.4 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA37655.1 - 1.6e-07 30.9 0.1 1.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA37655.1 - 1.2e-06 28.6 0.1 3.9e-06 27.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPA37655.1 - 5.4e-05 22.4 0.1 0.00057 19.1 0.1 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KPA37655.1 - 0.00024 21.6 0.3 0.00077 20.0 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPA37655.1 - 0.00029 20.0 0.7 0.00044 19.4 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.16 KPA37655.1 - 0.00054 19.6 0.1 0.088 12.4 0.1 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KPA37655.1 - 0.0011 18.2 0.2 0.0016 17.6 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KPA37655.1 - 0.0016 17.2 0.0 0.0063 15.3 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 KPA37655.1 - 0.0051 15.7 0.9 0.011 14.6 0.1 2.0 3 0 0 3 3 3 1 Tryptophan halogenase SE PF08491.10 KPA37655.1 - 0.0082 15.2 0.0 0.21 10.6 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.6 KPA37655.1 - 0.013 15.5 0.2 0.083 12.9 0.2 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KPA37655.1 - 0.063 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KPA37655.1 - 0.067 12.4 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Tir_receptor_C PF07489.11 KPA37655.1 - 0.097 12.6 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus FAD_oxidored PF12831.7 KPA37655.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Epimerase PF01370.21 KPA37656.1 - 2.5e-14 53.3 0.1 6.4e-13 48.7 0.1 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPA37656.1 - 1.5e-09 38.0 0.1 2.3e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPA37656.1 - 2e-09 37.4 0.3 4.1e-09 36.3 0.3 1.5 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KPA37656.1 - 3e-07 30.9 0.1 6.2e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KPA37656.1 - 1.2e-06 27.7 0.0 4.6e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPA37656.1 - 7.1e-06 25.4 0.3 0.00013 21.3 0.3 2.3 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KPA37656.1 - 0.00015 21.2 1.6 0.0057 16.1 0.3 2.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KPA37656.1 - 0.0028 16.8 0.1 0.0046 16.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein STAS PF01740.21 KPA37656.1 - 0.16 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 STAS domain GFO_IDH_MocA_C PF02894.17 KPA37657.1 - 5.9e-19 68.2 0.2 1.8e-18 66.6 0.2 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KPA37657.1 - 9.6e-17 61.9 0.0 2e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F-box-like PF12937.7 KPA37658.1 - 0.32 10.9 0.1 0.32 10.9 0.1 2.9 3 0 0 3 3 3 0 F-box-like Glyco_hydro_3_C PF01915.22 KPA37660.1 - 2.7e-56 190.8 0.0 1.2e-55 188.6 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPA37660.1 - 1.5e-52 179.0 0.0 2.5e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPA37660.1 - 1.6e-19 69.8 0.2 1.7e-18 66.5 0.1 2.4 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KPA37660.1 - 0.0011 18.8 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain GFA PF04828.14 KPA37661.1 - 1.2e-11 44.8 0.2 1.6e-11 44.4 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme HeLo PF14479.6 KPA37663.1 - 1.9e-16 60.5 1.5 2.4e-16 60.2 0.2 1.7 1 1 1 2 2 2 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 KPA37663.1 - 0.069 12.4 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase UTP15_C PF09384.10 KPA37664.1 - 7.4e-50 168.5 0.0 1.2e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KPA37664.1 - 6.1e-16 58.5 4.9 0.00032 21.4 0.1 5.3 6 0 0 6 6 5 3 WD domain, G-beta repeat Pkinase PF00069.25 KPA37664.1 - 1.2e-13 51.0 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA37664.1 - 4.8e-09 35.9 0.0 9.6e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 KPA37664.1 - 1.1e-05 25.6 0.1 0.25 11.7 0.0 3.1 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ank_5 PF13857.6 KPA37664.1 - 8.9e-05 22.7 0.1 0.00036 20.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KPA37664.1 - 0.0002 21.7 0.4 0.0015 18.9 0.0 2.8 3 0 0 3 3 2 1 Ankyrin repeat Ank_2 PF12796.7 KPA37664.1 - 0.00021 21.8 0.0 0.00087 19.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA37664.1 - 0.001 19.3 0.0 0.005 17.3 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeat Kinase-like PF14531.6 KPA37664.1 - 0.0043 16.4 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ank_4 PF13637.6 KPA37664.1 - 0.019 15.5 0.0 0.066 13.8 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RAB3GAP2_N PF14655.6 KPA37664.1 - 0.16 11.2 0.1 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DEAD PF00270.29 KPA37666.1 - 3.1e-17 62.9 0.1 6.6e-17 61.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KPA37666.1 - 6.3e-13 49.1 0.0 1.4e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Lentivirus_VIF PF05851.11 KPA37666.1 - 0.04 12.8 0.0 0.094 11.6 0.0 1.5 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) Fungal_trans PF04082.18 KPA37668.1 - 4.6e-11 42.2 0.3 4.4e-10 39.0 0.0 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KPA37669.1 - 4.2e-71 238.7 53.9 2.1e-37 128.6 16.2 3.5 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KPA37669.1 - 3.5e-37 126.2 7.9 2.6e-31 107.4 0.1 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 KPA37669.1 - 8.4e-34 117.0 0.0 4.8e-16 59.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KPA37669.1 - 7e-16 58.6 0.0 2.2e-15 57.0 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KPA37669.1 - 2.5e-07 30.1 33.0 4.8e-07 29.2 6.6 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KPA37669.1 - 1e-06 28.8 0.1 0.17 11.6 0.0 3.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KPA37669.1 - 2.4e-05 24.0 0.0 0.00037 20.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KPA37669.1 - 0.00011 22.1 0.2 0.0056 16.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KPA37669.1 - 0.00016 21.4 1.6 0.021 14.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KPA37669.1 - 0.0002 21.8 0.0 0.07 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KPA37669.1 - 0.0038 16.7 0.0 0.23 10.9 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KPA37669.1 - 0.0069 16.9 0.0 0.14 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPA37669.1 - 0.007 16.5 0.1 0.2 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KPA37669.1 - 0.01 16.3 0.2 1.8 9.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KPA37669.1 - 0.02 14.6 0.1 0.94 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KPA37669.1 - 0.03 14.6 1.2 0.76 10.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KPA37669.1 - 0.03 14.8 0.3 0.07 13.6 0.1 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 KPA37669.1 - 0.062 13.2 0.8 3.3 7.6 0.3 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 KPA37669.1 - 0.086 12.9 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 KPA37669.1 - 0.14 12.1 0.1 5.1 7.0 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KPA37669.1 - 0.15 12.4 0.1 5.3 7.5 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_13 PF13166.6 KPA37669.1 - 0.24 10.0 0.0 2.2 6.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KPA37669.1 - 0.25 10.6 0.5 49 3.1 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KPA37669.1 - 0.46 9.7 2.5 1.1 8.5 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_28 PF13521.6 KPA37669.1 - 0.46 10.7 1.5 0.96 9.7 0.3 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KPA37669.1 - 2.7 7.6 5.2 1.4 8.4 0.8 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain gag-asp_proteas PF13975.6 KPA37670.1 - 7.9e-10 39.2 0.0 0.00026 21.5 0.0 2.9 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KPA37670.1 - 1.8e-09 38.1 0.0 0.00048 20.7 0.0 2.6 2 1 0 2 2 2 2 Aspartyl protease Ank_2 PF12796.7 KPA37671.1 - 3.5e-20 72.4 0.6 1.8e-06 28.4 0.0 4.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA37671.1 - 2.3e-19 69.5 4.0 2.5e-05 24.7 0.1 6.7 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA37671.1 - 1.7e-12 46.3 5.2 0.13 12.9 0.1 7.0 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KPA37671.1 - 1e-10 41.6 0.6 0.054 14.0 0.1 6.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KPA37671.1 - 8.7e-10 38.7 7.6 0.0011 19.3 0.2 7.0 3 3 4 7 7 7 3 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KPA37671.1 - 0.0052 16.2 7.8 0.12 11.7 3.8 3.5 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Sec2p PF06428.11 KPA37671.1 - 0.034 14.1 7.6 0.86 9.6 0.3 3.9 4 0 0 4 4 4 0 GDP/GTP exchange factor Sec2p Imm49 PF15575.6 KPA37671.1 - 0.11 12.3 1.7 0.32 10.7 0.1 2.3 2 0 0 2 2 2 0 Immunity protein 49 SesA PF17107.5 KPA37671.1 - 0.2 11.9 5.7 0.058 13.6 0.6 2.7 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Acetyltransf_3 PF13302.7 KPA37673.1 - 5.5e-11 43.3 0.0 7.2e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA37673.1 - 4e-10 40.0 0.0 5.2e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KPA37673.1 - 1.2e-05 25.5 0.0 5.1e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA37673.1 - 0.00072 19.9 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA37673.1 - 0.013 15.4 0.0 0.037 14.0 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.6 KPA37673.1 - 0.045 13.4 0.0 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA37673.1 - 0.093 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 KPA37674.1 - 1.5e-82 277.9 16.5 1.8e-82 277.6 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA37674.1 - 2.2e-16 59.7 27.3 2.2e-16 59.7 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA37674.1 - 4.9e-08 31.9 13.1 0.00027 19.6 2.8 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 KPA37674.1 - 0.00011 21.6 4.8 0.00011 21.6 4.8 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KPA37674.1 - 0.38 9.5 14.1 0.0064 15.4 7.2 1.5 2 0 0 2 2 2 0 MFS_1 like family Glyco_hydro_39 PF01229.17 KPA37675.1 - 5.4e-07 28.6 0.1 7.5e-07 28.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Fungal_trans PF04082.18 KPA37676.1 - 2.1e-10 40.1 2.0 9.1e-10 38.0 2.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1156 PF06634.12 KPA37676.1 - 0.094 12.8 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) DDE_Tnp_1_assoc PF13808.6 KPA37676.1 - 0.14 12.2 0.0 0.44 10.6 0.0 1.8 1 0 0 1 1 1 0 DDE_Tnp_1-associated Glyco_hydro_127 PF07944.12 KPA37677.1 - 4e-109 365.5 0.6 5.4e-109 365.0 0.6 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 M20_dimer PF07687.14 KPA37678.1 - 4.5e-13 49.1 0.0 1.8e-12 47.2 0.0 2.0 2 1 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KPA37678.1 - 6.4e-10 39.1 0.0 1.1e-09 38.3 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 FA_desaturase PF00487.24 KPA37679.1 - 5.6e-21 75.5 18.0 9.7e-21 74.7 18.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase VCBS PF13517.6 KPA37680.1 - 3.3e-32 110.9 25.4 2.7e-11 43.9 0.7 8.5 5 2 3 8 8 8 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 KPA37680.1 - 1.2e-08 34.6 3.2 0.44 9.9 0.0 5.9 3 3 3 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_2 PF13472.6 KPA37680.1 - 1.5e-08 35.3 0.0 3.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 KPA37680.1 - 4.1e-07 30.0 13.0 0.04 14.1 0.1 4.9 4 0 0 4 4 4 4 FG-GAP repeat Lipase_GDSL PF00657.22 KPA37680.1 - 5.1e-06 26.6 0.0 8.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BBS2_C PF14782.6 KPA37680.1 - 0.011 14.5 0.1 2.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal EF-hand_1 PF00036.32 KPA37680.1 - 1.8 8.3 4.7 70 3.3 0.2 3.8 3 0 0 3 3 3 0 EF hand DUF373 PF04123.13 KPA37681.1 - 0.14 11.6 4.1 0.19 11.2 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) MARVEL PF01284.23 KPA37681.1 - 0.29 11.2 10.5 0.51 10.3 9.7 1.9 1 1 0 1 1 1 0 Membrane-associating domain Cupin_1 PF00190.22 KPA37682.1 - 1.7e-15 56.9 1.2 2.5e-15 56.4 1.2 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KPA37682.1 - 0.0071 16.0 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Cupin domain DIOX_N PF14226.6 KPA37683.1 - 1.7e-25 90.1 0.1 2.6e-25 89.5 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPA37683.1 - 4e-19 69.0 0.0 8.8e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 KPA37684.1 - 5.6e-94 315.4 31.7 6.6e-94 315.2 31.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NB-ARC PF00931.22 KPA37685.1 - 4.6e-18 65.3 0.0 9.1e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 KPA37685.1 - 8.4e-12 45.2 7.1 2.3e-06 27.8 0.0 4.6 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPA37685.1 - 5.3e-09 35.6 1.2 0.13 12.5 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPA37685.1 - 5.8e-08 32.3 3.8 0.53 10.5 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 KPA37685.1 - 2.1e-06 28.2 0.0 9.2e-05 22.9 0.0 2.9 1 1 0 1 1 1 1 AAA ATPase domain TPR_10 PF13374.6 KPA37685.1 - 2.5e-06 27.2 4.3 0.52 10.3 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPA37685.1 - 9.5e-05 22.8 2.1 0.45 11.1 0.3 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KPA37685.1 - 0.00015 21.3 3.2 0.13 11.6 0.0 2.7 2 1 0 3 3 3 2 MalT-like TPR region TPR_7 PF13176.6 KPA37685.1 - 0.00016 21.4 0.0 1.9 8.7 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ATPase_2 PF01637.18 KPA37685.1 - 0.00054 19.9 0.2 0.007 16.3 0.0 2.7 2 1 0 3 3 3 1 ATPase domain predominantly from Archaea TPR_16 PF13432.6 KPA37685.1 - 0.001 19.7 5.9 0.0064 17.1 0.1 4.4 3 2 0 3 3 3 1 Tetratricopeptide repeat Goodbye PF17109.5 KPA37685.1 - 0.0024 18.3 0.0 0.0086 16.5 0.0 2.1 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain TPR_14 PF13428.6 KPA37685.1 - 0.0044 17.7 13.6 4.8 8.3 0.1 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA37685.1 - 0.012 15.9 0.1 1.4 9.2 0.3 2.8 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KPA37685.1 - 0.036 13.9 3.2 6.2 6.8 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 KPA37685.1 - 0.069 13.4 0.0 0.31 11.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain TPR_4 PF07721.14 KPA37685.1 - 5.8 7.9 19.2 0.8 10.5 2.1 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPA37685.1 - 7.6 7.4 8.3 41 5.1 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat uDENN PF03456.18 KPA37686.1 - 0.086 13.6 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 uDENN domain Dabb PF07876.12 KPA37687.1 - 1.4e-26 92.9 0.0 1.6e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Asparaginase_C PF17763.1 KPA37689.1 - 1.2e-11 44.9 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain DUF1887 PF09002.11 KPA37690.1 - 0.088 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) ArsR PF09824.9 KPA37693.1 - 0.21 11.2 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 ArsR transcriptional regulator ABC2_membrane PF01061.24 KPA37694.1 - 7e-38 130.2 19.7 7e-38 130.2 19.7 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KPA37694.1 - 1.9e-25 90.0 0.1 1.4e-24 87.2 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KPA37694.1 - 1.4e-05 25.1 0.0 0.24 11.2 0.0 2.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPA37694.1 - 0.0061 16.3 0.1 0.016 15.0 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KPA37694.1 - 0.0065 15.6 29.6 0.045 12.8 29.6 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KPA37694.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 KPA37694.1 - 0.024 14.2 0.0 0.063 12.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 KPA37694.1 - 0.056 14.0 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KPA37694.1 - 0.062 12.7 0.0 0.88 9.0 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KPA37694.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ThrE PF06738.12 KPA37694.1 - 0.077 12.4 2.6 0.24 10.8 2.6 1.8 1 0 0 1 1 1 0 Putative threonine/serine exporter AAA_22 PF13401.6 KPA37694.1 - 0.089 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KPA37694.1 - 0.092 13.2 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KPA37694.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KPA37694.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KPA37694.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PDR_CDR PF06422.12 KPA37694.1 - 0.21 11.5 0.9 0.85 9.6 0.0 2.5 2 0 0 2 2 2 0 CDR ABC transporter DUF4436 PF14494.6 KPA37694.1 - 3.2 7.0 4.7 10 5.3 4.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4436) EGF PF00008.27 KPA37694.1 - 3.2 8.1 16.4 0.81 10.0 0.7 4.4 3 0 0 3 3 3 0 EGF-like domain DUF5325 PF17259.2 KPA37694.1 - 3.3 7.7 10.3 0.26 11.2 3.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5325) NGP1NT PF08153.12 KPA37696.1 - 1.7e-49 167.3 0.6 2.9e-49 166.5 0.6 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KPA37696.1 - 6.1e-15 55.3 0.0 9.3e-12 45.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KPA37696.1 - 1.1e-05 25.1 0.1 0.00035 20.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KPA37696.1 - 0.001 19.1 0.6 0.33 11.0 0.1 3.4 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 KPA37696.1 - 0.02 14.8 0.0 0.052 13.4 0.0 1.6 1 1 0 1 1 1 0 RsgA GTPase Arf PF00025.21 KPA37696.1 - 0.03 13.8 0.0 5.3 6.5 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF218 PF02698.17 KPA37697.1 - 2.2e-05 24.5 0.0 4.4e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 DUF218 domain SMN PF06003.12 KPA37697.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Aa_trans PF01490.18 KPA37699.1 - 4.3e-78 262.8 23.6 5.3e-78 262.5 23.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PhoLip_ATPase_C PF16212.5 KPA37699.1 - 7.4 6.2 10.6 3.7 7.2 2.3 2.8 2 1 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal LSM PF01423.22 KPA37700.1 - 1.7e-19 69.2 0.0 1.9e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 LSM domain ADH_N_2 PF16884.5 KPA37700.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase adh_short_C2 PF13561.6 KPA37702.1 - 2.7e-62 210.4 2.3 3.1e-62 210.2 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA37702.1 - 2.3e-38 131.7 1.5 2.7e-38 131.4 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA37702.1 - 1.5e-13 51.0 0.7 2.3e-13 50.4 0.7 1.2 1 0 0 1 1 1 1 KR domain Glyco_hydro_99 PF16317.5 KPA37702.1 - 0.049 12.7 0.1 0.16 11.1 0.1 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase family 99 YjeF_N PF03853.15 KPA37702.1 - 0.052 13.4 0.4 0.1 12.5 0.3 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus MFS_1 PF07690.16 KPA37703.1 - 7.2e-38 130.4 25.1 1.1e-37 129.8 25.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MWFE PF15879.5 KPA37703.1 - 0.043 14.0 2.6 0.089 13.0 0.0 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit IDO PF01231.18 KPA37704.1 - 1.6e-149 498.4 0.0 1.9e-149 498.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KPA37704.1 - 0.0036 16.1 0.0 1 8.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) Aminotran_5 PF00266.19 KPA37705.1 - 3.3e-09 36.2 0.0 6.8e-09 35.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KPA37705.1 - 0.079 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KPA37705.1 - 0.21 10.1 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.18 KPA37706.1 - 1.1e-12 47.5 0.1 2e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lactonase PF10282.9 KPA37707.1 - 8.3e-44 150.2 0.0 1.1e-43 149.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Thioredoxin_8 PF13905.6 KPA37707.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like DNA_pack_N PF02500.15 KPA37709.1 - 0.0078 16.1 0.2 0.013 15.4 0.2 1.3 1 0 0 1 1 1 1 Probable DNA packing protein, N-terminus CSN5_C PF18323.1 KPA37709.1 - 0.026 15.4 1.7 0.93 10.4 0.1 2.9 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain HALZ PF02183.18 KPA37709.1 - 0.027 14.7 7.0 0.19 12.0 2.5 3.7 3 1 1 4 4 4 0 Homeobox associated leucine zipper DUF1664 PF07889.12 KPA37709.1 - 0.052 13.6 7.0 1.3 9.1 0.1 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KPA37709.1 - 0.083 13.1 19.9 0.014 15.6 8.4 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SBP_bac_6 PF13343.6 KPA37709.1 - 0.16 11.4 0.0 0.49 9.8 0.0 1.8 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein Taxilin PF09728.9 KPA37709.1 - 0.22 10.7 16.3 0.078 12.1 0.4 2.7 1 1 1 2 2 2 0 Myosin-like coiled-coil protein SICA_beta PF12878.7 KPA37709.1 - 0.22 11.7 3.5 1.3 9.2 0.1 2.9 1 1 2 3 3 3 0 SICA extracellular beta domain PEARLI-4 PF05278.12 KPA37709.1 - 0.32 10.6 10.3 0.86 9.1 1.6 3.1 1 1 2 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4600 PF15372.6 KPA37709.1 - 0.34 11.3 12.0 1.1 9.6 0.3 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4600) UPF0242 PF06785.11 KPA37709.1 - 0.87 9.7 24.0 0.41 10.7 14.5 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rootletin PF15035.6 KPA37709.1 - 0.92 9.5 18.0 0.065 13.3 4.1 2.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.9 KPA37709.1 - 1.6 7.8 18.5 3.6 6.6 2.9 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 KPA37709.1 - 2.2 8.8 12.2 0.89 10.1 1.5 3.0 2 1 1 3 3 3 0 Protein of unknown function DUF16 NYD-SP28_assoc PF14775.6 KPA37709.1 - 2.4 8.3 11.3 0.34 11.0 0.7 4.0 3 1 1 4 4 4 0 Sperm tail C-terminal domain Fez1 PF06818.15 KPA37709.1 - 2.5 8.5 17.3 2.3 8.6 3.2 2.2 1 1 1 2 2 2 0 Fez1 YabA PF06156.13 KPA37709.1 - 2.5 8.8 16.1 25 5.6 6.5 4.0 1 1 1 3 3 3 0 Initiation control protein YabA DnaJ PF00226.31 KPA37710.1 - 5.8e-06 26.3 0.2 5.8e-06 26.3 0.2 2.6 3 0 0 3 3 3 1 DnaJ domain Staphylokinase PF02821.16 KPA37710.1 - 0.053 14.0 0.1 0.14 12.6 0.1 1.7 1 0 0 1 1 1 0 Staphylokinase/Streptokinase family MIEAP PF16026.5 KPA37710.1 - 0.89 9.7 3.5 1.6 8.9 0.9 2.6 2 1 0 2 2 2 0 Mitochondria-eating protein CoA_trans PF01144.23 KPA37712.1 - 0.059 12.8 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 Coenzyme A transferase IFT20 PF14931.6 KPA37712.1 - 0.082 13.1 0.5 0.16 12.2 0.2 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Deltameth_res PF16020.5 KPA37713.1 - 0.022 14.6 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Deltamethrin resistance Tetraspanin PF00335.20 KPA37713.1 - 0.028 14.1 4.6 0.034 13.9 4.6 1.1 1 0 0 1 1 1 0 Tetraspanin family Patatin PF01734.22 KPA37715.1 - 2e-10 41.2 0.5 2.7e-08 34.2 0.5 3.0 2 1 0 2 2 2 1 Patatin-like phospholipase zf-RING_UBOX PF13445.6 KPA37715.1 - 0.0086 16.1 5.1 0.019 15.0 3.1 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KPA37715.1 - 0.032 14.1 2.8 0.11 12.3 2.8 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPA37715.1 - 0.12 12.3 6.4 0.1 12.5 4.3 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 ArfGap PF01412.18 KPA37715.1 - 0.18 11.9 2.0 0.34 11.0 2.0 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf-C3HC4_3 PF13920.6 KPA37715.1 - 3.1 7.7 10.8 0.064 13.1 2.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HALZ PF02183.18 KPA37716.1 - 0.0015 18.7 0.1 0.0023 18.1 0.1 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF4047 PF13256.6 KPA37716.1 - 0.14 12.3 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) MFS_1 PF07690.16 KPA37718.1 - 3.7e-35 121.5 25.8 9.8e-35 120.1 26.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF543 PF04418.12 KPA37718.1 - 0.42 10.6 4.2 0.21 11.6 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) SpoVAB PF13782.6 KPA37718.1 - 1 9.7 13.8 0.03 14.6 4.4 2.8 2 1 1 3 3 3 0 Stage V sporulation protein AB Pkinase PF00069.25 KPA37719.1 - 2.4e-68 230.4 0.0 3.6e-68 229.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA37719.1 - 2.4e-33 115.5 0.0 3e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPA37719.1 - 0.00036 19.6 0.0 0.017 14.1 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KPA37719.1 - 0.00057 19.9 0.0 0.0039 17.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KPA37719.1 - 0.00075 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KPA37719.1 - 0.0077 15.3 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 KPA37719.1 - 0.023 14.0 0.1 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Beta_helix PF13229.6 KPA37720.1 - 4e-13 49.5 16.0 2.4e-11 43.8 8.6 2.2 1 1 1 2 2 2 2 Right handed beta helix region Chondroitinas_B PF14592.6 KPA37720.1 - 2.7e-07 29.8 0.4 1.1e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 Chondroitinase B DUF1565 PF07602.11 KPA37720.1 - 0.025 13.9 0.2 0.025 13.9 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1565) FBPase PF00316.20 KPA37722.1 - 2.3e-22 79.4 0.0 3.9e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KPA37722.1 - 0.32 10.5 1.5 0.32 10.5 0.1 1.6 2 0 0 2 2 2 0 Inositol monophosphatase family EthD PF07110.11 KPA37723.1 - 0.029 15.5 0.4 0.18 13.0 0.4 1.9 1 1 0 1 1 1 0 EthD domain Thioredoxin PF00085.20 KPA37724.1 - 4.4e-14 52.3 0.1 5.6e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Cas1_AcylT PF07779.12 KPA37725.1 - 2.7e-116 389.3 6.0 4.8e-116 388.5 6.0 1.3 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KPA37725.1 - 0.0048 16.7 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p adh_short PF00106.25 KPA37726.1 - 1.3e-28 99.8 0.0 2.7e-28 98.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37726.1 - 7e-21 74.9 0.0 1.2e-20 74.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA37726.1 - 0.005 16.8 0.1 0.065 13.1 0.1 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA37726.1 - 0.017 14.6 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family EF-hand_10 PF14788.6 KPA37726.1 - 0.09 12.7 0.0 0.29 11.0 0.0 1.8 1 1 0 1 1 1 0 EF hand AA_permease_2 PF13520.6 KPA37727.1 - 2.6e-48 164.9 44.6 3.5e-48 164.5 44.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA37727.1 - 2.6e-27 95.6 36.3 3.6e-27 95.1 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease NTP_transf_6 PF06042.11 KPA37728.1 - 1.4e-54 184.3 0.4 1.7e-54 184.0 0.4 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase Aldedh PF00171.22 KPA37729.1 - 6.7e-136 453.5 0.0 7.7e-136 453.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KPA37729.1 - 0.0042 16.2 0.0 0.0073 15.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) AP3D1 PF06375.11 KPA37730.1 - 0.12 12.6 5.4 1.2 9.4 5.7 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Glyco_hydro_cc PF11790.8 KPA37731.1 - 8.3e-52 176.1 0.0 1.5e-51 175.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core Aldose_epim PF01263.20 KPA37732.1 - 7.2e-47 160.1 0.2 9.3e-47 159.8 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Cupin_2 PF07883.11 KPA37733.1 - 2.7e-08 33.4 0.1 0.00018 21.1 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 KPA37733.1 - 1.4e-07 31.2 0.0 2.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KPA37733.1 - 0.08 12.6 0.1 0.61 9.8 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Hydrophobin_2 PF06766.11 KPA37734.1 - 1e-26 92.7 9.8 1.3e-26 92.3 9.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Homeobox_KN PF05920.11 KPA37735.1 - 5.9e-21 74.1 0.6 1.3e-20 73.0 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KPA37735.1 - 2.1e-08 33.9 5.3 3.8e-08 33.1 1.4 2.6 2 0 0 2 2 2 1 Homeodomain Homeodomain PF00046.29 KPA37736.1 - 9.8e-09 34.9 1.7 1.6e-06 27.8 0.0 2.9 2 0 0 2 2 2 2 Homeodomain Rhodanese PF00581.20 KPA37736.1 - 4.4e-08 33.6 0.0 1.3e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain PIG-X PF08320.12 KPA37737.1 - 2.8e-63 213.7 0.0 4.5e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 Zn_clus PF00172.18 KPA37738.1 - 1.3e-08 34.8 8.5 3.6e-08 33.4 8.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA37739.1 - 2.2e-09 36.8 0.2 3e-09 36.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37739.1 - 0.22 11.7 2.8 0.38 10.9 2.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH_1 PF00378.20 KPA37740.1 - 1.4e-26 93.3 0.0 1.7e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA37740.1 - 2.6e-16 60.1 0.0 3.2e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 KPA37741.1 - 6.2e-62 209.5 0.0 8.6e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA37741.1 - 6.8e-10 39.8 0.1 1.9e-09 38.4 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_1 PF00561.20 KPA37742.1 - 2.1e-14 53.8 0.0 3.1e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA37742.1 - 9.7e-14 52.5 1.3 1.2e-13 52.2 1.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA37742.1 - 1.4e-10 40.9 0.1 1.6e-09 37.4 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 TRAM PF01938.20 KPA37742.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 TRAM domain Ndr PF03096.14 KPA37742.1 - 0.15 10.7 0.0 3.1 6.4 0.0 2.0 2 0 0 2 2 2 0 Ndr family ECH_1 PF00378.20 KPA37743.1 - 9.3e-29 100.5 0.0 1e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA37743.1 - 4.4e-15 56.0 0.0 5e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Fungal_trans PF04082.18 KPA37745.1 - 2.6e-15 56.2 1.0 3.5e-15 55.8 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KPA37746.1 - 1.3e-47 162.3 2.4 7.1e-46 156.7 2.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA37746.1 - 9.8e-44 149.1 2.1 1.2e-43 148.8 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA37746.1 - 2e-15 57.1 0.4 2.9e-15 56.7 0.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KPA37746.1 - 0.0083 16.0 0.3 0.016 15.1 0.3 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KPA37746.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 KPA37746.1 - 0.017 15.4 0.2 0.028 14.7 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KPA37746.1 - 0.058 12.8 0.1 0.089 12.2 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KPA37746.1 - 0.14 11.2 0.5 0.22 10.6 0.2 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain 4HBT_3 PF13622.6 KPA37747.1 - 3.6e-43 148.6 0.0 4.2e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily NIL PF09383.10 KPA37747.1 - 0.13 12.1 0.2 0.41 10.5 0.1 1.8 2 0 0 2 2 2 0 NIL domain MFS_1 PF07690.16 KPA37748.1 - 5.5e-30 104.5 32.1 5.5e-30 104.5 32.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.6 KPA37748.1 - 0.9 10.0 5.3 3.7 8.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Zn_clus PF00172.18 KPA37749.1 - 2.3e-06 27.6 10.1 3.6e-06 27.0 10.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1192 PF06698.11 KPA37749.1 - 0.13 12.3 0.3 0.34 11.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) BUD22 PF09073.10 KPA37750.1 - 2.9 7.2 46.5 3.2 7.0 46.5 1.0 1 0 0 1 1 1 0 BUD22 HLH PF00010.26 KPA37751.1 - 2.8e-12 46.4 0.1 2.8e-12 46.4 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TSC22 PF01166.18 KPA37751.1 - 0.28 11.5 0.8 0.47 10.8 0.1 1.6 2 0 0 2 2 2 0 TSC-22/dip/bun family CDC45 PF02724.14 KPA37751.1 - 0.44 8.8 9.4 0.64 8.2 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein MerR-DNA-bind PF09278.11 KPA37751.1 - 0.65 10.6 8.9 0.093 13.3 3.7 2.1 2 0 0 2 2 2 0 MerR, DNA binding Apt1 PF10351.9 KPA37751.1 - 0.66 8.8 4.5 0.78 8.5 4.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 KPA37751.1 - 7.2 5.2 5.7 8.8 4.9 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 KPA37751.1 - 9.1 4.9 4.8 11 4.7 4.8 1.1 1 0 0 1 1 1 0 Presenilin Aldo_ket_red PF00248.21 KPA37752.1 - 6.6e-27 94.5 0.0 5e-13 48.9 0.0 3.0 1 1 1 2 2 2 2 Aldo/keto reductase family HRDC PF00570.23 KPA37752.1 - 0.19 11.7 0.0 4.3 7.4 0.0 2.6 3 0 0 3 3 3 0 HRDC domain HIT PF01230.23 KPA37753.1 - 2.1e-17 63.7 0.0 3.4e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KPA37753.1 - 1.3e-05 25.6 0.0 2.7e-05 24.6 0.0 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KPA37753.1 - 0.0061 16.4 0.1 0.035 14.0 0.0 2.2 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 1 DNA_RNApol_7kD PF03604.13 KPA37754.1 - 8.8e-11 41.3 0.9 1.2e-10 40.9 0.9 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_9 PF14369.6 KPA37754.1 - 0.004 17.4 0.3 0.0074 16.5 0.3 1.5 1 1 0 1 1 1 1 zinc-ribbon PhnA_Zn_Ribbon PF08274.12 KPA37754.1 - 0.008 16.1 0.2 0.013 15.5 0.2 1.3 1 0 0 1 1 1 1 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.10 KPA37754.1 - 0.009 16.1 0.7 0.021 15.0 0.7 1.6 1 1 0 1 1 1 1 Zinc ribbon domain zf_Rg PF17915.1 KPA37754.1 - 0.011 15.1 0.2 4.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Reverse gyrase zinc finger zf-C2HC5 PF06221.13 KPA37754.1 - 0.033 14.2 0.1 0.041 13.9 0.1 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DnaJ_CXXCXGXG PF00684.19 KPA37754.1 - 0.039 14.3 0.5 0.053 13.9 0.5 1.3 1 0 0 1 1 1 0 DnaJ central domain HypA PF01155.19 KPA37754.1 - 0.067 13.2 0.2 0.079 13.0 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 KPA37754.1 - 0.08 13.3 1.3 1.4 9.3 0.1 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 KPA37754.1 - 0.097 12.7 1.8 0.94 9.5 2.0 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-TFIIB PF13453.6 KPA37754.1 - 0.15 11.4 1.5 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger YacG PF03884.14 KPA37754.1 - 0.15 11.8 0.3 2 8.2 0.0 2.5 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG ATP_bind_1 PF03029.17 KPA37755.1 - 1.7e-71 240.8 0.0 2.3e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KPA37755.1 - 4.7e-05 22.5 0.0 0.031 13.3 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KPA37755.1 - 0.00022 20.8 0.0 0.012 15.1 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KPA37755.1 - 0.00067 19.9 0.0 0.0031 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KPA37755.1 - 0.00068 19.7 0.0 0.019 15.1 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KPA37755.1 - 0.00073 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA37755.1 - 0.0011 19.4 0.0 0.003 17.9 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 KPA37755.1 - 0.0016 18.1 0.0 0.021 14.4 0.0 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 KPA37755.1 - 0.0017 17.6 0.0 0.056 12.6 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.6 KPA37755.1 - 0.0021 18.2 0.6 0.011 15.9 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KPA37755.1 - 0.003 17.3 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KPA37755.1 - 0.0033 16.6 0.0 0.0084 15.3 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain SRP54 PF00448.22 KPA37755.1 - 0.0047 16.6 0.0 0.082 12.5 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PRK PF00485.18 KPA37755.1 - 0.0053 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 KPA37755.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.18 KPA37755.1 - 0.008 15.7 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KPA37755.1 - 0.015 15.2 0.1 5.7 6.8 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase Arf PF00025.21 KPA37755.1 - 0.015 14.7 0.0 1.6 8.2 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 KPA37755.1 - 0.019 15.5 0.4 0.13 12.8 0.0 2.5 3 1 1 4 4 3 0 AAA domain AAA_23 PF13476.6 KPA37755.1 - 0.02 15.4 0.1 5.7 7.4 0.3 2.4 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KPA37755.1 - 0.022 14.4 0.3 0.65 9.6 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase Roc PF08477.13 KPA37755.1 - 0.028 14.7 0.0 3.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KPA37755.1 - 0.037 13.6 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KPA37755.1 - 0.047 13.0 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 KPA37755.1 - 0.071 13.0 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 KPA37755.1 - 0.11 12.6 0.1 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Na_trans_assoc PF06512.13 KPA37755.1 - 0.23 11.7 5.6 0.44 10.8 5.6 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated DUF1682 PF07946.14 KPA37755.1 - 0.43 9.7 4.4 0.87 8.7 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Vfa1 PF08432.10 KPA37755.1 - 2.5 8.4 6.8 4.7 7.5 6.8 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop52 PF05997.12 KPA37756.1 - 5.2e-55 186.6 0.0 6.2e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.8 KPA37756.1 - 0.18 12.0 0.5 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair CTV_P6 PF06706.11 KPA37756.1 - 0.22 11.3 0.0 0.45 10.3 0.0 1.4 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein Jiraiya PF15038.6 KPA37758.1 - 0.0019 17.7 1.0 0.0029 17.1 1.0 1.2 1 0 0 1 1 1 1 Jiraiya Mannitol_dh_C PF08125.13 KPA37759.1 - 2.6e-75 253.1 0.0 3.6e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KPA37759.1 - 4.8e-48 163.1 0.0 9.2e-48 162.2 0.0 1.5 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Cullin_binding PF03556.15 KPA37759.1 - 0.2 12.1 1.1 0.82 10.1 1.1 2.1 1 1 0 1 1 1 0 Cullin binding CAP PF00188.26 KPA37760.1 - 7.9e-17 62.3 0.1 1.5e-16 61.4 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family HLH PF00010.26 KPA37761.1 - 2e-09 37.2 1.6 3.3e-09 36.5 1.6 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 KPA37761.1 - 0.015 15.5 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper YabA PF06156.13 KPA37761.1 - 0.12 13.0 0.0 0.22 12.2 0.0 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Cylicin_N PF15241.6 KPA37761.1 - 0.13 12.4 0.3 9.8 6.4 0.2 2.4 2 0 0 2 2 2 0 Cylicin N-terminus TAL_FSA PF00923.19 KPA37762.1 - 1.7e-32 112.9 0.0 2.8e-32 112.2 0.0 1.3 2 0 0 2 2 2 1 Transaldolase/Fructose-6-phosphate aldolase UBD PF16455.5 KPA37762.1 - 0.16 12.3 0.0 0.95 9.7 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-binding domain adh_short_C2 PF13561.6 KPA37763.1 - 4e-52 177.1 0.7 4.9e-52 176.8 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA37763.1 - 7e-37 126.8 1.2 1e-36 126.2 0.9 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPA37763.1 - 1.6e-15 57.5 0.7 2e-15 57.2 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA37763.1 - 3.8e-06 26.6 0.2 1.4e-05 24.7 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA37763.1 - 1.3e-05 24.4 0.1 2.3e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KPA37763.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KPA37763.1 - 0.00012 21.3 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KPA37763.1 - 0.0038 17.5 0.1 0.0079 16.4 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ELFV_dehydrog PF00208.21 KPA37763.1 - 0.04 13.6 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.6 KPA37763.1 - 0.044 13.7 0.6 0.088 12.7 0.3 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Peptidase_S8 PF00082.22 KPA37764.1 - 1.6e-34 119.6 11.8 2.2e-34 119.1 11.2 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KPA37764.1 - 2.1e-17 63.6 0.1 3.7e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Endonuclease_5 PF04493.14 KPA37764.1 - 0.045 13.4 0.6 0.12 12.1 0.3 1.8 2 0 0 2 2 2 0 Endonuclease V GFA PF04828.14 KPA37765.1 - 9e-22 77.2 0.3 1.1e-11 44.9 0.2 3.5 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.6 KPA37765.1 - 0.85 10.1 5.6 1 9.8 2.7 2.3 2 0 0 2 2 2 0 Cysteine-rich CWC Rpr2 PF04032.16 KPA37765.1 - 1.2 9.5 4.5 6 7.2 0.0 3.0 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Yippee-Mis18 PF03226.14 KPA37765.1 - 3.1 8.1 5.8 18 5.6 0.6 3.4 4 0 0 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_ribbon_SprT PF17283.2 KPA37765.1 - 4.9 7.1 11.0 5.9 6.9 0.0 4.0 4 2 0 4 4 4 0 SprT-like zinc ribbon domain Methyltransf_23 PF13489.6 KPA37766.1 - 7.2e-20 71.5 0.0 1.5e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA37766.1 - 1.1e-09 38.9 0.0 7.6e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA37766.1 - 1.1e-08 35.0 0.0 1.4e-07 31.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA37766.1 - 3.3e-06 27.7 0.0 8.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA37766.1 - 7.4e-06 26.6 0.0 6.1e-05 23.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KPA37766.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 KPA37766.1 - 0.025 14.0 0.0 0.055 12.8 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KPA37766.1 - 0.076 12.3 0.0 1.9 7.7 0.0 2.6 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 KPA37766.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.16 KPA37767.1 - 3.9e-29 101.7 32.9 5.3e-29 101.2 32.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPA37767.1 - 0.0012 18.3 7.1 0.0012 18.3 7.1 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB COesterase PF00135.28 KPA37768.1 - 3.7e-96 323.0 0.0 4.7e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA37768.1 - 2.5e-06 27.5 0.6 1.4e-05 25.0 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold HAD_2 PF13419.6 KPA37769.1 - 4.8e-08 33.3 0.0 6.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA37769.1 - 0.036 14.4 0.0 0.29 11.4 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Git3 PF11710.8 KPA37770.1 - 6.5e-18 65.2 11.6 2.3e-17 63.4 11.6 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KPA37770.1 - 4.2e-13 49.2 1.4 4.2e-13 49.2 1.4 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 KPA37770.1 - 5e-05 22.6 9.3 0.00029 20.1 7.1 2.1 1 1 1 2 2 2 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 KPA37770.1 - 0.0015 18.6 0.6 0.0071 16.4 0.0 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term SK_channel PF03530.14 KPA37770.1 - 0.04 13.9 0.3 0.04 13.9 0.3 2.0 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Amidohydro_1 PF01979.20 KPA37771.1 - 4e-55 187.5 0.0 5.3e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPA37771.1 - 7.8e-13 48.7 0.2 1.8e-09 37.6 0.0 2.4 3 0 0 3 3 3 2 Amidohydrolase family A_deaminase PF00962.22 KPA37771.1 - 0.097 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase YlbD_coat PF14071.6 KPA37771.1 - 0.1 12.9 0.0 3.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Putative coat protein Glyco_hydro_127 PF07944.12 KPA37772.1 - 1.2e-141 472.7 0.3 1.4e-141 472.5 0.3 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 DUF1254 PF06863.12 KPA37772.1 - 0.067 13.3 0.0 8.3 6.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1254) DUF1295 PF06966.12 KPA37773.1 - 0.18 11.3 1.6 16 4.9 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Sec5 PF15469.6 KPA37776.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 p450 PF00067.22 KPA37778.1 - 1.5e-69 234.9 0.0 1.9e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Yip1 PF04893.17 KPA37779.1 - 5.1e-07 29.6 12.7 2.3e-05 24.2 4.3 2.5 2 1 0 2 2 2 2 Yip1 domain RCC1 PF00415.18 KPA37780.1 - 6.4e-64 212.4 0.2 3.4e-11 43.6 0.2 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KPA37780.1 - 1.7e-36 123.3 29.9 1.6e-08 34.1 0.2 6.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 KPA37780.1 - 0.039 13.8 3.1 4.4 7.2 0.2 3.5 4 1 1 5 5 5 0 Peptidase family C25, C terminal ig-like domain Presenilin PF01080.17 KPA37780.1 - 6.7 5.4 8.3 11 4.7 8.3 1.3 1 0 0 1 1 1 0 Presenilin p450 PF00067.22 KPA37782.1 - 1e-24 87.2 0.6 8.8e-24 84.1 0.6 2.0 1 1 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.11 KPA37783.1 - 2.6e-07 30.3 0.6 4.4e-07 29.5 0.6 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KPA37783.1 - 1.2e-05 25.0 0.4 1.6e-05 24.6 0.4 1.4 1 1 0 1 1 1 1 Cupin Na_Ca_ex PF01699.24 KPA37784.1 - 1.8e-25 89.6 40.2 2e-15 57.0 16.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3425 PF11905.8 KPA37785.1 - 1e-12 48.1 1.6 1.8e-12 47.3 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KPA37785.1 - 0.0019 18.3 7.9 0.0033 17.5 7.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor Takusan PF04822.13 KPA37785.1 - 0.018 14.9 0.3 0.049 13.5 0.3 1.8 1 0 0 1 1 1 0 Takusan RP-C_C PF11800.8 KPA37785.1 - 0.047 13.8 2.0 0.077 13.1 2.0 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DIRP PF06584.13 KPA37785.1 - 0.049 13.8 0.7 2 8.6 0.0 2.5 2 0 0 2 2 2 0 DIRP MFS_1 PF07690.16 KPA37786.1 - 3.1e-33 115.2 57.7 3.1e-32 111.9 45.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 KPA37786.1 - 2.3e-05 23.4 0.0 2.3e-05 23.4 0.0 2.1 2 1 0 2 2 2 1 LacY proton/sugar symporter DUF5549 PF17703.1 KPA37786.1 - 0.36 10.5 1.8 21 4.7 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5549) Aa_trans PF01490.18 KPA37790.1 - 0.0024 16.6 5.3 0.0027 16.5 5.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_3 PF07859.13 KPA37791.1 - 1.3e-52 178.8 1.1 7.5e-52 176.3 0.4 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPA37791.1 - 3.2e-07 29.5 0.0 4.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KPA37791.1 - 1.7e-06 27.5 0.3 3.6e-06 26.4 0.2 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPA37791.1 - 0.0035 16.9 0.1 0.017 14.6 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 KPA37791.1 - 0.031 13.8 0.1 0.34 10.4 0.1 2.2 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 KPA37791.1 - 0.094 11.6 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Aldo_ket_red PF00248.21 KPA37792.1 - 2.9e-60 204.0 0.0 3.6e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Y1_Tnp PF01797.16 KPA37792.1 - 0.046 13.8 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Transposase IS200 like Lactamase_B PF00753.27 KPA37793.1 - 8.6e-08 32.4 0.6 1.3e-07 31.8 0.6 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPA37793.1 - 0.0016 18.0 0.0 0.0087 15.6 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Acetyltransf_2 PF00797.17 KPA37794.1 - 6.8e-43 147.2 0.0 1.1e-42 146.5 0.0 1.3 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 KPA37794.1 - 0.015 15.8 0.1 0.053 14.0 0.0 1.9 2 1 0 2 2 2 0 Transglutaminase-like superfamily Fungal_trans PF04082.18 KPA37795.1 - 8.9e-21 74.1 0.1 1.5e-20 73.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37795.1 - 1.1e-09 38.3 4.8 2.7e-09 37.0 4.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 KPA37796.1 - 1.3e-52 179.3 0.0 1.8e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA37796.1 - 1.9e-05 24.6 0.0 0.0037 17.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold AMP-binding PF00501.28 KPA37797.1 - 1.8e-65 221.2 0.0 3.3e-65 220.3 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA37797.1 - 3.7e-15 56.7 0.1 9.9e-15 55.3 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Tyrosinase PF00264.20 KPA37798.1 - 1.6e-24 87.4 0.7 3.5e-24 86.3 0.7 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase F-box PF00646.33 KPA37799.1 - 0.1 12.5 0.3 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 F-box domain HET PF06985.11 KPA37801.1 - 1.4e-27 96.9 0.0 2.8e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CCDC158 PF15921.5 KPA37801.1 - 0.17 9.6 0.1 0.25 9.1 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 p450 PF00067.22 KPA37803.1 - 6.9e-71 239.4 0.0 8.7e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3176 PF11374.8 KPA37804.1 - 5.6e-17 61.9 1.4 1.8e-15 57.0 0.6 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3176) DUF1154 PF06631.11 KPA37804.1 - 0.22 11.6 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) ADH_zinc_N_2 PF13602.6 KPA37805.1 - 2.3e-17 64.3 0.0 5.8e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KPA37805.1 - 1.3e-10 41.3 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 KPA37806.1 - 4.2e-06 26.0 2.8 6.3e-06 25.4 2.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S10 PF00450.22 KPA37807.1 - 4.3e-75 253.7 0.1 5.6e-75 253.3 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Amidohydro_3 PF07969.11 KPA37808.1 - 3.8e-62 211.3 0.0 4.3e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KPA37808.1 - 6.6e-12 45.4 0.4 5e-07 29.3 0.2 2.9 2 1 0 2 2 2 2 Amidohydrolase family SpoVS PF04232.12 KPA37808.1 - 0.0002 21.0 0.3 0.00054 19.6 0.3 1.7 1 0 0 1 1 1 1 Stage V sporulation protein S (SpoVS) NUDIX PF00293.28 KPA37809.1 - 4e-07 30.1 0.0 6.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain TIG_2 PF18020.1 KPA37809.1 - 0.038 14.6 0.0 0.12 13.0 0.0 1.8 2 0 0 2 2 2 0 TIG domain found in plexin Abhydrolase_6 PF12697.7 KPA37810.1 - 8e-11 43.0 0.1 2.5e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA37810.1 - 1.2e-05 24.7 0.1 3.1e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 TPR_19 PF14559.6 KPA37810.1 - 0.00063 20.2 0.1 1.7 9.2 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPA37810.1 - 0.0039 17.2 0.0 1.5 9.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPA37810.1 - 0.0046 16.9 0.1 6.2 7.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Chlorophyllase2 PF12740.7 KPA37810.1 - 0.015 14.2 0.0 0.032 13.2 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme TPR_MalT PF17874.1 KPA37810.1 - 0.085 12.2 1.1 3 7.1 0.1 2.5 1 1 0 1 1 1 0 MalT-like TPR region TPR_12 PF13424.6 KPA37810.1 - 0.12 12.6 0.8 0.82 10.0 0.1 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_8 PF06259.12 KPA37810.1 - 0.15 11.7 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase MFS_1 PF07690.16 KPA37811.1 - 6.3e-28 97.7 40.0 8.7e-28 97.2 29.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Phage_holin_7_1 PF16081.5 KPA37811.1 - 1.3 9.2 7.9 0.24 11.6 0.5 2.5 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Sugar_tr PF00083.24 KPA37811.1 - 1.5 7.5 40.6 0.026 13.4 3.2 3.8 2 2 1 3 3 3 0 Sugar (and other) transporter MFS_1 PF07690.16 KPA37812.1 - 1.2e-28 100.0 29.6 1.2e-28 100.0 29.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KPA37813.1 - 2e-66 224.4 0.8 2.4e-66 224.1 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro-kuma_activ PF09286.11 KPA37815.1 - 1.1e-33 116.5 0.0 2.4e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KPA37815.1 - 5.2e-06 25.9 0.0 8.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Subtilase family DUF1351 PF07083.11 KPA37815.1 - 0.21 11.3 0.1 13 5.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1351) NmrA PF05368.13 KPA37816.1 - 4.7e-38 131.1 0.0 7.2e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA37816.1 - 1.3e-13 51.2 0.0 2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA37816.1 - 0.00067 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KPA37816.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 KPA37816.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KPA37819.1 - 1.2e-07 31.4 0.0 9.7e-07 28.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPA37819.1 - 2.2e-05 24.4 0.0 3.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KPA37819.1 - 0.00024 20.7 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HET PF06985.11 KPA37820.1 - 4.5e-12 46.5 6.2 1.2e-09 38.6 1.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Methyltransf_11 PF08241.12 KPA37821.1 - 7.4e-07 29.7 0.0 1.6e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA37821.1 - 8e-06 26.5 0.0 1.8e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA37821.1 - 0.00059 19.7 0.0 0.00095 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA37821.1 - 0.016 14.5 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KPA37821.1 - 0.02 15.6 0.0 0.034 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KPA37821.1 - 0.042 13.6 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KPA37822.1 - 4.9e-06 26.6 8.3 8.7e-06 25.8 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA37822.1 - 6.4e-05 22.1 0.1 0.00016 20.8 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Thioredoxin PF00085.20 KPA37823.1 - 4.9e-25 87.5 0.1 5.9e-25 87.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KPA37823.1 - 9.4e-08 32.3 0.0 2.4e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KPA37823.1 - 3.5e-07 30.7 0.3 7.7e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KPA37823.1 - 3.1e-06 26.8 0.0 3.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KPA37823.1 - 0.0014 18.5 0.2 0.0052 16.7 0.2 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KPA37823.1 - 0.0023 18.1 0.1 0.0035 17.5 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KPA37823.1 - 0.0032 17.3 0.0 0.0038 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KPA37823.1 - 0.0043 16.8 0.6 0.47 10.1 0.2 2.1 1 1 1 2 2 2 2 Redoxin TraF PF13728.6 KPA37823.1 - 0.0057 16.5 0.2 0.0094 15.8 0.2 1.4 1 1 0 1 1 1 1 F plasmid transfer operon protein DIM1 PF02966.16 KPA37823.1 - 0.013 15.3 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 DSBA PF01323.20 KPA37823.1 - 0.027 14.2 2.1 3.2 7.5 0.2 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 KPA37823.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Cu_amine_oxid PF01179.20 KPA37825.1 - 8.9e-162 538.7 0.0 1.1e-161 538.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KPA37825.1 - 8.3e-22 77.5 0.2 1.5e-20 73.4 0.0 2.4 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KPA37825.1 - 4.2e-12 46.1 0.0 7.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Abhydrolase_6 PF12697.7 KPA37826.1 - 3.4e-13 50.7 0.0 3.9e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KPA37826.1 - 2.9e-05 24.3 0.0 0.0046 17.1 0.0 2.3 2 1 0 2 2 2 2 Thioesterase domain Hydrolase_4 PF12146.8 KPA37826.1 - 0.0082 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KPA37826.1 - 0.062 12.9 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase MFS_1 PF07690.16 KPA37827.1 - 9.4e-32 110.3 25.7 1.3e-31 109.8 25.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KPA37827.1 - 0.022 14.6 0.7 0.022 14.6 0.7 3.0 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MNSV_P7B PF06692.11 KPA37827.1 - 0.08 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein TFR_dimer PF04253.15 KPA37828.1 - 1.7e-25 89.4 0.0 3.1e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KPA37828.1 - 7.8e-22 77.9 0.0 1.3e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KPA37828.1 - 9.6e-10 38.4 0.3 9.6e-10 38.4 0.3 2.5 2 1 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KPA37828.1 - 0.00039 20.2 0.0 0.00095 18.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KPA37828.1 - 0.063 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Nicastrin DUF4446 PF14584.6 KPA37828.1 - 0.12 12.3 0.4 0.22 11.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Fungal_trans PF04082.18 KPA37829.1 - 0.014 14.5 0.1 0.034 13.2 0.1 1.7 2 1 0 2 2 2 0 Fungal specific transcription factor domain Methyltr_RsmB-F PF01189.17 KPA37830.1 - 4.6e-33 114.5 0.0 2.9e-25 89.1 0.0 3.2 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KPA37830.1 - 0.094 12.8 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase GTP1_OBG PF01018.22 KPA37831.1 - 1.6e-41 141.4 0.3 5e-31 107.4 0.8 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KPA37831.1 - 3e-24 85.3 0.0 8e-24 83.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPA37831.1 - 1.7e-08 34.2 0.2 1.2e-07 31.4 0.1 2.2 3 0 0 3 3 3 1 Ferrous iron transport protein B MeaB PF03308.16 KPA37831.1 - 0.011 14.7 6.6 0.53 9.2 0.0 2.6 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RPN2_C PF18004.1 KPA37831.1 - 0.012 15.6 2.4 0.02 14.8 2.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Arf PF00025.21 KPA37831.1 - 0.022 14.2 0.1 0.69 9.3 0.1 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC_tran PF00005.27 KPA37831.1 - 0.026 15.0 1.3 0.035 14.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Pox_Ag35 PF03286.14 KPA37831.1 - 0.068 13.0 4.0 0.16 11.8 4.0 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 KPA37831.1 - 0.12 11.8 11.2 0.19 11.1 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Dynamin_N PF00350.23 KPA37831.1 - 0.4 10.7 5.5 9 6.3 0.0 3.2 3 1 0 4 4 4 0 Dynamin family AAA_23 PF13476.6 KPA37831.1 - 1.8 9.0 8.4 7.7 7.0 2.2 2.8 3 0 0 3 3 3 0 AAA domain CDC45 PF02724.14 KPA37831.1 - 2.6 6.2 7.0 0.77 8.0 3.5 1.7 2 0 0 2 2 2 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 KPA37831.1 - 3 8.0 13.6 0.56 10.4 10.0 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 ABC_tran_CTD PF16326.5 KPA37833.1 - 0.00028 21.1 4.7 0.00028 21.1 4.7 6.1 3 1 1 6 6 6 2 ABC transporter C-terminal domain APG6_N PF17675.1 KPA37833.1 - 0.0054 17.3 23.1 0.0054 17.3 23.1 4.2 2 1 1 4 4 4 2 Apg6 coiled-coil region Occludin_ELL PF07303.13 KPA37833.1 - 0.045 14.5 1.8 0.045 14.5 1.8 4.7 2 1 3 5 5 5 0 Occludin homology domain DUF4239 PF14023.6 KPA37833.1 - 0.12 12.0 7.3 0.82 9.3 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Baculo_PEP_C PF04513.12 KPA37833.1 - 0.21 11.7 4.9 3.3 7.7 0.3 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 KPA37833.1 - 0.65 9.3 6.6 1.6 8.0 6.6 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HHH_6 PF14579.6 KPA37833.1 - 0.75 10.1 6.1 0.45 10.8 0.4 2.9 2 1 1 3 3 3 0 Helix-hairpin-helix motif FlaC_arch PF05377.11 KPA37833.1 - 7.6 7.0 12.0 11 6.4 0.3 4.6 2 1 1 4 4 4 0 Flagella accessory protein C (FlaC) RNA_pol_Rpb5_C PF01191.19 KPA37834.1 - 4.6e-34 116.1 0.5 3.4e-33 113.4 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KPA37834.1 - 8.5e-26 90.4 0.0 1.3e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KPA37834.1 - 0.027 14.5 0.0 0.081 13.0 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease Sulfatase PF00884.23 KPA37837.1 - 1.9e-14 53.8 0.2 3.5e-14 52.9 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPA37837.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KPA37837.1 - 0.027 13.1 0.0 0.068 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_3_C PF01915.22 KPA37838.1 - 4.9e-34 118.1 1.0 2.8e-31 109.1 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPA37838.1 - 8.4e-34 117.4 0.0 1.4e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPA37838.1 - 9e-05 22.5 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1349 PF07081.11 KPA37838.1 - 0.082 12.6 0.7 0.15 11.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) DUF3302 PF11742.8 KPA37840.1 - 0.0017 18.5 1.4 0.0017 18.5 1.4 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3302) D-ser_dehydrat PF14031.6 KPA37842.1 - 2.3e-20 73.0 0.1 4.1e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KPA37842.1 - 2.6e-15 56.7 0.0 3.8e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain NAD_binding_4 PF07993.12 KPA37843.1 - 1.3e-39 136.0 0.0 1.9e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KPA37843.1 - 1.5e-18 66.7 0.0 2.3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KPA37843.1 - 4.9e-14 52.4 0.0 7.8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPA37843.1 - 3.6e-06 26.3 0.1 0.0061 15.7 0.0 2.8 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KPA37843.1 - 4.1e-06 26.0 0.1 1.3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KPA37843.1 - 2.5e-05 23.8 0.0 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KPA37843.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KPA37843.1 - 0.0047 16.9 0.2 0.012 15.5 0.2 1.7 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 KPA37843.1 - 0.057 13.8 0.0 0.25 11.7 0.0 2.2 1 1 0 1 1 1 0 Phosphopantetheine attachment site Beta-lactamase PF00144.24 KPA37844.1 - 1.1e-38 133.3 0.0 1.9e-38 132.6 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase DIT1_PvcA PF05141.12 KPA37845.1 - 9.2e-74 248.4 0.0 1.7e-73 247.5 0.0 1.5 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein HpcH_HpaI PF03328.14 KPA37845.1 - 3.3e-24 85.3 0.0 5.8e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family TauD PF02668.16 KPA37845.1 - 4.3e-24 85.8 0.0 1e-23 84.5 0.0 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Methyltransf_25 PF13649.6 KPA37845.1 - 2.6e-09 37.7 0.0 9.6e-09 35.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA37845.1 - 1.3e-07 31.6 0.0 1.3e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA37845.1 - 4e-07 30.7 0.0 1.1e-06 29.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA37845.1 - 8.1e-07 29.0 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA37845.1 - 1.4e-05 25.6 0.0 4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CsiD PF08943.10 KPA37845.1 - 0.14 11.2 0.3 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 CsiD Aldedh PF00171.22 KPA37846.1 - 7.6e-155 515.9 0.4 8.6e-155 515.7 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KPA37846.1 - 0.0088 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) MFS_1 PF07690.16 KPA37847.1 - 7.4e-32 110.6 18.7 7.4e-32 110.6 18.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PAN_1 PF00024.26 KPA37848.1 - 1.2e-06 28.3 1.1 1.8e-06 27.8 0.1 1.7 2 0 0 2 2 2 1 PAN domain DUF2070 PF09843.9 KPA37849.1 - 0.068 11.5 5.2 0.056 11.7 4.3 1.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Sensor_TM1 PF13755.6 KPA37849.1 - 0.075 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain Glyco_transf_90 PF05686.12 KPA37850.1 - 1e-06 27.9 0.8 3.5e-06 26.2 0.8 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 90 GATA PF00320.27 KPA37851.1 - 4.4e-08 32.6 5.9 1.2e-07 31.2 5.9 1.8 1 0 0 1 1 1 1 GATA zinc finger HATPase_c PF02518.26 KPA37852.1 - 1.3e-19 70.7 0.0 3.3e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPA37852.1 - 3e-13 49.9 0.1 8.1e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KPA37852.1 - 1e-08 35.1 0.0 3e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KPA37852.1 - 0.0033 17.7 0.0 0.0096 16.2 0.0 1.9 1 1 0 1 1 1 1 GAF domain Tube PF17212.3 KPA37853.1 - 0.13 12.4 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Tail tubular protein MFS_1 PF07690.16 KPA37855.1 - 2e-37 129.0 43.1 4.9e-36 124.4 43.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA37855.1 - 3.2e-06 26.3 11.1 3.2e-06 26.3 11.1 3.7 3 2 1 4 4 4 2 Sugar (and other) transporter LysM PF01476.20 KPA37856.1 - 9e-09 35.3 2.9 1 9.5 0.0 6.0 6 0 0 6 6 6 4 LysM domain P4Ha_N PF08336.11 KPA37856.1 - 0.0066 16.5 0.0 14 5.7 0.0 3.1 3 0 0 3 3 3 2 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region UPF0203 PF05254.12 KPA37856.1 - 0.011 16.0 10.6 3.4 8.0 0.1 4.9 5 0 0 5 5 5 0 Uncharacterised protein family (UPF0203) Glyco_hydro_18 PF00704.28 KPA37860.1 - 1.1e-42 146.9 0.5 1.6e-42 146.3 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KPA37860.1 - 6.8e-07 29.7 12.6 6.8e-07 29.7 12.6 4.0 3 1 0 3 3 3 1 Chitin recognition protein LysM PF01476.20 KPA37860.1 - 1.2e-06 28.4 0.0 0.0077 16.3 0.0 2.7 2 0 0 2 2 2 2 LysM domain Tannase PF07519.11 KPA37861.1 - 3.9e-66 223.9 0.6 2.6e-50 171.7 0.5 2.0 2 0 0 2 2 2 2 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KPA37861.1 - 0.0025 17.1 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA37861.1 - 0.0046 16.6 0.1 0.007 16.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA37861.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyco_hydro_7 PF00840.20 KPA37861.1 - 0.034 12.9 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 Glyco_transf_28 PF03033.20 KPA37862.1 - 9.7e-23 80.8 0.0 2.3e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 KPA37862.1 - 0.058 13.4 0.0 0.79 9.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KPA37862.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase PreAtp-grasp PF18604.1 KPA37865.1 - 0.017 14.8 0.0 0.076 12.7 0.0 1.9 2 0 0 2 2 2 0 Pre ATP-grasp domain Aspzincin_M35 PF14521.6 KPA37868.1 - 0.0075 16.8 0.4 0.11 13.0 0.1 2.4 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase DUF3147 PF11345.8 KPA37870.1 - 0.027 14.8 0.7 0.027 14.8 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) Peptidase_M56 PF05569.11 KPA37870.1 - 9.3 5.3 11.2 1.4 8.0 6.9 1.8 2 1 0 2 2 2 0 BlaR1 peptidase M56 COesterase PF00135.28 KPA37871.1 - 2e-86 290.9 0.0 2.5e-86 290.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA37871.1 - 0.00013 21.9 0.4 0.00067 19.6 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA37871.1 - 0.00022 20.8 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family p450 PF00067.22 KPA37872.1 - 4.6e-53 180.6 0.0 6.1e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 KPA37873.1 - 2.6e-07 29.8 0.0 5.9e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37873.1 - 1.1e-05 25.4 10.2 1.1e-05 25.4 10.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KPA37874.1 - 3e-09 36.9 11.3 5.6e-09 36.0 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA37874.1 - 6e-07 28.6 0.2 9.3e-07 28.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KPA37875.1 - 0.0023 16.8 2.8 0.0023 16.8 2.8 2.3 1 1 2 3 3 3 1 Fungal specific transcription factor domain Methyltransf_11 PF08241.12 KPA37878.1 - 2.8e-13 50.3 0.0 4.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA37878.1 - 7e-13 49.1 0.0 1.6e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA37878.1 - 5.9e-10 39.8 0.0 2e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA37878.1 - 1.9e-06 27.8 0.0 3.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA37878.1 - 6.2e-06 26.1 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KPA37878.1 - 0.007 15.7 0.0 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KPA37878.1 - 0.095 12.2 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_9 PF08003.11 KPA37878.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 KPA37878.1 - 0.14 12.0 0.0 6.4 6.6 0.0 2.9 3 0 0 3 3 3 0 Hypothetical methyltransferase DREV PF05219.12 KPA37878.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase MGC-24 PF05283.11 KPA37879.1 - 0.00023 21.7 3.0 0.00036 21.0 3.0 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 KPA37879.1 - 5.4 7.0 19.8 10 6.1 19.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein FAD_binding_3 PF01494.19 KPA37880.1 - 2.7e-24 86.1 0.0 7.9e-24 84.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KPA37880.1 - 0.00027 20.3 0.1 0.41 9.8 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPA37880.1 - 0.0014 17.5 0.1 0.14 11.0 0.1 2.6 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KPA37880.1 - 0.0044 17.2 0.3 0.011 15.9 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA37880.1 - 0.011 15.3 0.4 0.021 14.4 0.4 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPA37880.1 - 0.028 13.5 0.0 0.056 12.5 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KPA37880.1 - 0.095 11.9 0.9 0.52 9.5 0.2 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA37880.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KPA37880.1 - 0.16 12.5 0.1 0.64 10.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPA37880.1 - 0.23 10.5 0.6 0.38 9.8 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Peptidase_M28 PF04389.17 KPA37881.1 - 2.1e-32 112.4 0.0 2.8e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KPA37881.1 - 6.9e-06 25.9 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KPA37881.1 - 0.014 14.9 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 0 Nicastrin MFS_1 PF07690.16 KPA37882.1 - 6.8e-12 45.0 39.1 6.8e-12 45.0 39.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA37882.1 - 0.00052 18.6 3.2 0.00052 18.6 3.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GST_N PF02798.20 KPA37883.1 - 4e-12 46.3 0.1 1.3e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPA37883.1 - 8.3e-12 45.2 0.0 1.6e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPA37883.1 - 1e-11 45.0 0.1 3.8e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPA37883.1 - 3e-10 40.4 0.0 5.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPA37883.1 - 7.7e-10 38.9 0.0 1.4e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPA37883.1 - 2.8e-06 27.2 0.0 9.2e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KPA37883.1 - 0.052 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein tRNA_anti-like PF12869.7 KPA37883.1 - 0.1 12.2 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 tRNA_anti-like MFS_1 PF07690.16 KPA37885.1 - 1.8e-34 119.2 20.6 1.8e-34 119.2 20.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily AA_permease_2 PF13520.6 KPA37886.1 - 1.2e-19 70.5 21.8 1.3e-19 70.3 21.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA37886.1 - 7.2e-06 24.9 16.2 9.4e-06 24.5 16.2 1.1 1 0 0 1 1 1 1 Amino acid permease IspA PF04279.15 KPA37886.1 - 5.7 7.1 15.7 5.4 7.2 10.8 2.8 2 1 0 2 2 2 0 Intracellular septation protein A Fungal_trans_2 PF11951.8 KPA37887.1 - 7.4e-23 81.0 0.3 4.3e-17 62.0 0.3 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37887.1 - 1.1e-08 35.1 5.4 2.1e-08 34.1 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LIP PF03583.14 KPA37888.1 - 6.5e-51 173.3 0.0 9.4e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KPA37888.1 - 0.12 11.8 0.0 5.9 6.3 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Zn_clus PF00172.18 KPA37889.1 - 4.7e-07 29.8 12.8 1.1e-06 28.6 12.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VanZ PF04892.12 KPA37889.1 - 0.0036 18.0 0.0 0.0065 17.1 0.0 1.5 1 1 0 1 1 1 1 VanZ like family adh_short PF00106.25 KPA37890.1 - 1.9e-17 63.4 0.0 2.5e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA37890.1 - 2.3e-11 43.7 0.0 3.6e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA37890.1 - 1.1e-05 25.4 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 KPA37890.1 - 0.0039 17.1 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family Polysacc_synt_2 PF02719.15 KPA37890.1 - 0.064 12.4 0.2 0.1 11.7 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Methyltransf_33 PF10017.9 KPA37890.1 - 0.099 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Pec_lyase_C PF00544.19 KPA37891.1 - 6.8e-17 61.8 9.9 1.3e-15 57.5 9.9 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KPA37891.1 - 3.9e-07 30.1 14.5 0.00049 20.0 7.3 2.3 1 1 1 2 2 2 2 Right handed beta helix region Acetyltransf_7 PF13508.7 KPA37892.1 - 1.8e-07 31.5 0.0 2.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA37892.1 - 2.6e-07 30.9 0.0 3.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA37892.1 - 1.1e-06 28.5 0.0 2.3e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Band_7_1 PF13421.6 KPA37892.1 - 0.061 13.0 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 SPFH domain-Band 7 family FR47 PF08445.10 KPA37892.1 - 0.081 12.9 0.2 0.46 10.5 0.2 2.2 1 1 1 2 2 2 0 FR47-like protein Peptidase_M20 PF01546.28 KPA37893.1 - 2.2e-22 79.8 1.5 1.4e-16 60.8 0.2 2.4 3 0 0 3 3 3 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPA37893.1 - 6.7e-21 74.2 0.2 1.2e-20 73.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KPA37893.1 - 0.00022 21.0 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 KPA37893.1 - 0.045 12.8 0.2 0.85 8.6 0.2 2.2 1 1 0 2 2 2 0 M42 glutamyl aminopeptidase Response_reg PF00072.24 KPA37894.1 - 1.6e-22 79.8 0.3 2.9e-22 78.9 0.3 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KPA37894.1 - 2.8e-21 76.1 0.0 5.6e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KPA37894.1 - 4.8e-06 26.5 1.4 1e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KPA37894.1 - 0.0001 22.5 0.0 0.00038 20.7 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 KPA37894.1 - 0.00045 20.2 0.0 0.0014 18.6 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KPA37894.1 - 0.0024 17.9 0.0 0.0068 16.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.6 KPA37894.1 - 0.061 13.6 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 GAF domain PAS_4 PF08448.10 KPA37894.1 - 0.088 13.1 0.0 0.35 11.1 0.0 2.1 1 0 0 1 1 1 0 PAS fold Fungal_trans PF04082.18 KPA37895.1 - 7.1e-16 58.0 3.3 2.6e-15 56.2 3.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37895.1 - 1.4e-05 25.1 13.6 2.7e-05 24.2 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GAGE PF05831.11 KPA37895.1 - 1.4 9.5 6.0 15 6.2 2.0 2.4 2 0 0 2 2 2 0 GAGE protein Acetyltransf_3 PF13302.7 KPA37896.1 - 4.3e-12 46.9 0.0 6.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KPA37896.1 - 0.0028 17.8 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA37896.1 - 0.018 15.3 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TMEM52 PF14979.6 KPA37897.1 - 0.035 14.0 0.9 0.066 13.1 0.9 1.4 1 0 0 1 1 1 0 Transmembrane 52 Recep_L_domain PF01030.24 KPA37898.1 - 2.5e-05 24.4 0.1 5 7.3 0.0 4.9 1 1 3 4 4 4 3 Receptor L domain SKG6 PF08693.10 KPA37898.1 - 0.0022 17.4 3.1 0.0044 16.4 3.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF3971 PF13116.6 KPA37898.1 - 0.0087 15.7 0.4 0.018 14.6 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF4328 PF14219.6 KPA37898.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Glyco_hydro_2_N PF02837.18 KPA37899.1 - 6.7e-14 52.1 2.5 2.6e-12 46.9 2.5 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KPA37899.1 - 1.4e-10 41.8 1.0 2.4e-09 37.9 0.0 3.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KPA37899.1 - 5.6e-08 32.2 0.1 1e-06 28.1 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain BetaGal_dom4_5 PF13364.6 KPA37899.1 - 0.013 16.1 0.2 0.027 15.0 0.2 1.5 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain MT PF12777.7 KPA37900.1 - 0.0026 16.9 2.5 0.0059 15.7 1.8 1.7 1 1 1 2 2 2 1 Microtubule-binding stalk of dynein motor UPF0242 PF06785.11 KPA37900.1 - 0.0092 16.1 4.6 0.017 15.3 4.6 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 KPA37900.1 - 0.013 15.7 10.1 0.5 10.6 0.8 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MAD PF05557.13 KPA37900.1 - 0.027 12.9 5.8 0.04 12.3 5.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein PEARLI-4 PF05278.12 KPA37900.1 - 0.075 12.6 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) PMC2NT PF08066.12 KPA37900.1 - 0.09 13.5 0.4 0.29 11.8 0.4 1.9 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Fez1 PF06818.15 KPA37900.1 - 0.12 12.8 9.5 0.47 10.9 5.8 2.6 2 1 0 2 2 2 0 Fez1 AAA_13 PF13166.6 KPA37900.1 - 0.15 10.7 3.4 0.25 9.9 3.4 1.4 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 KPA37900.1 - 0.28 10.5 9.2 0.5 9.7 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KPA37900.1 - 2 7.2 7.5 7.1 5.4 7.6 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein GAT PF03127.14 KPA37900.1 - 2.4 8.5 4.9 0.95 9.8 0.3 2.7 4 0 0 4 4 3 0 GAT domain APG6_N PF17675.1 KPA37900.1 - 2.7 8.5 8.7 2.6 8.6 1.6 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region AA_permease_2 PF13520.6 KPA37901.1 - 4.9e-64 216.7 54.4 6.1e-64 216.4 54.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA37901.1 - 1.2e-32 113.2 50.1 1.7e-32 112.7 50.1 1.1 1 0 0 1 1 1 1 Amino acid permease fn3 PF00041.21 KPA37902.1 - 0.067 13.5 0.1 12 6.3 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III domain Glyco_hydro_15 PF00723.21 KPA37903.1 - 5.3e-97 325.4 0.0 6.7e-97 325.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KPA37903.1 - 7.1e-25 86.7 1.2 1.5e-24 85.7 1.2 1.6 1 0 0 1 1 1 1 Starch binding domain CBM_48 PF02922.18 KPA37903.1 - 0.028 14.8 0.0 0.063 13.6 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) HET PF06985.11 KPA37904.1 - 2.8e-07 31.0 1.0 0.00015 22.1 0.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Acetyltransf_1 PF00583.25 KPA37905.1 - 5.3e-16 58.9 0.0 6.4e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA37905.1 - 4.7e-10 39.8 0.0 6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA37905.1 - 1e-07 31.8 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KPA37905.1 - 3.2e-06 27.9 0.0 4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA37905.1 - 8.2e-06 25.8 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TPR_15 PF13429.6 KPA37905.1 - 0.019 14.2 0.2 0.04 13.1 0.1 1.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Acetyltransf_CG PF14542.6 KPA37905.1 - 0.036 14.2 0.0 0.079 13.1 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 KPA37905.1 - 0.05 13.2 0.2 0.061 12.9 0.2 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_4 PF13420.7 KPA37905.1 - 0.06 13.5 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ADH_N PF08240.12 KPA37906.1 - 4.8e-16 58.6 0.0 9.6e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA37906.1 - 6.6e-09 35.8 0.0 0.0037 17.3 0.0 3.0 2 1 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA37906.1 - 0.083 13.9 0.0 0.23 12.5 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_C PF03720.15 KPA37907.1 - 0.0018 18.7 0.0 0.0028 18.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 KPA37907.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NOA36 PF06524.12 KPA37907.1 - 0.66 9.3 9.6 0.79 9.0 9.6 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 KPA37907.1 - 1.2 8.2 11.4 1.5 7.8 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.6 KPA37907.1 - 1.6 9.1 15.9 3.1 8.2 15.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 KPA37907.1 - 8.1 4.4 9.5 10 4.1 9.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 KPA37908.1 - 3.2e-11 42.8 0.4 3.2e-11 42.8 0.4 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA37908.1 - 1.6e-06 27.3 0.1 1.6e-06 27.3 0.1 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 KPA37908.1 - 5.4 5.4 22.8 0.094 11.2 7.5 2.9 2 1 1 3 3 3 0 MFS/sugar transport protein Glyco_hydro_61 PF03443.14 KPA37909.1 - 7.4e-46 156.7 0.1 1.3e-45 155.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4407 PF14362.6 KPA37912.1 - 0.014 14.8 6.4 0.02 14.3 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Alanine_zipper PF11839.8 KPA37912.1 - 0.16 12.3 13.6 0.32 11.4 13.6 1.4 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Borrelia_P83 PF05262.11 KPA37912.1 - 0.2 10.1 2.3 0.26 9.7 2.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2968 PF11180.8 KPA37912.1 - 0.41 10.3 8.7 0.62 9.7 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) HET PF06985.11 KPA37913.1 - 4.4e-27 95.2 1.8 2.3e-26 92.9 1.8 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NurA PF09376.10 KPA37913.1 - 0.073 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 NurA domain Aldedh PF00171.22 KPA37914.1 - 4.5e-16 58.4 0.1 1.8e-13 49.9 0.0 2.9 1 1 0 2 2 2 2 Aldehyde dehydrogenase family Cupin_2 PF07883.11 KPA37916.1 - 1.1e-07 31.4 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KPA37916.1 - 0.027 14.1 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF3723 PF12520.8 KPA37917.1 - 5.9e-34 117.6 0.0 1.7e-30 106.2 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Helicase_C PF00271.31 KPA37918.1 - 3e-14 53.3 0.0 8.2e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPA37918.1 - 1.8e-09 37.6 0.0 4.6e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Peptidase_S8 PF00082.22 KPA37918.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Subtilase family Tox-ODYAM1 PF15642.6 KPA37920.1 - 0.0045 16.0 4.7 0.0059 15.6 4.7 1.2 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus HMMR_N PF15905.5 KPA37920.1 - 0.006 16.1 11.5 0.0073 15.8 11.5 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal ApoLp-III PF07464.11 KPA37920.1 - 0.0083 16.2 14.2 0.02 15.0 14.2 1.6 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Golgin_A5 PF09787.9 KPA37920.1 - 0.022 14.3 17.3 0.033 13.6 17.2 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 VSG_B PF13206.6 KPA37920.1 - 0.024 13.9 7.3 0.028 13.7 7.3 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Condensin2nSMC PF12422.8 KPA37920.1 - 0.066 13.4 2.0 0.11 12.7 2.0 1.3 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit DUF4527 PF15030.6 KPA37920.1 - 0.072 12.5 8.7 0.074 12.5 8.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4527) Exonuc_VII_L PF02601.15 KPA37920.1 - 0.11 12.1 10.1 0.13 11.8 10.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 KPA37920.1 - 0.11 10.5 6.1 0.13 10.2 6.1 1.1 1 0 0 1 1 1 0 Prominin DUF1759 PF03564.15 KPA37920.1 - 0.11 12.4 6.1 0.35 10.8 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) TMPIT PF07851.13 KPA37920.1 - 0.12 11.6 11.8 0.16 11.2 11.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 KPA37920.1 - 0.12 12.4 14.4 0.18 11.9 14.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TssR PF17643.1 KPA37920.1 - 0.15 10.0 5.1 0.19 9.6 5.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR Cor1 PF04803.12 KPA37920.1 - 0.16 12.2 16.6 0.26 11.5 16.6 1.4 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region PIN PF01850.21 KPA37920.1 - 0.19 12.3 1.1 0.72 10.4 1.1 1.8 1 1 0 1 1 1 0 PIN domain Sds3 PF08598.11 KPA37920.1 - 0.23 11.4 14.6 1.2 9.1 14.6 1.9 1 1 0 1 1 1 0 Sds3-like AAA_13 PF13166.6 KPA37920.1 - 0.27 9.8 7.9 0.33 9.5 7.9 1.1 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.16 KPA37920.1 - 0.37 9.6 5.0 0.47 9.3 5.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.8 KPA37920.1 - 0.43 9.8 20.1 1.4 8.1 19.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 KPA37920.1 - 0.55 9.5 12.9 0.73 9.1 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM195 PF14799.6 KPA37920.1 - 0.76 10.2 10.0 0.67 10.3 7.8 1.9 1 1 1 2 2 2 0 FAM195 family FUSC PF04632.12 KPA37920.1 - 0.87 8.0 6.3 1 7.8 6.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_23 PF13476.6 KPA37920.1 - 1 9.8 8.2 1.2 9.6 8.2 1.1 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 KPA37920.1 - 1.1 7.8 12.1 1.9 7.0 12.1 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Vps53_N PF04100.12 KPA37920.1 - 1.2 8.0 11.6 1.2 8.0 9.9 1.8 1 1 2 3 3 3 0 Vps53-like, N-terminal OmpH PF03938.14 KPA37920.1 - 1.4 9.2 26.9 0.21 12.0 18.7 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) EDS1_EP PF18117.1 KPA37920.1 - 1.5 9.4 4.8 5.5 7.5 0.4 2.2 1 1 1 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain DUF1515 PF07439.11 KPA37920.1 - 1.8 8.6 7.0 1.5 8.9 3.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) HrpB2 PF09487.10 KPA37920.1 - 2.1 8.8 10.7 1 9.8 0.8 3.0 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB2) ISG65-75 PF11727.8 KPA37920.1 - 2.4 7.3 10.5 0.71 9.1 4.8 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein Jnk-SapK_ap_N PF09744.9 KPA37920.1 - 3 8.1 17.6 12 6.1 17.6 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 FAM76 PF16046.5 KPA37920.1 - 3.3 7.0 9.4 4.2 6.6 9.4 1.1 1 0 0 1 1 1 0 FAM76 protein Fib_alpha PF08702.10 KPA37920.1 - 4.1 7.6 13.8 0.83 9.8 7.7 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4633 PF15464.6 KPA37920.1 - 4.4 7.5 10.3 6.6 6.9 0.2 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4633) DUF87 PF01935.17 KPA37920.1 - 6 6.9 6.8 9.6 6.2 6.8 1.4 1 1 0 1 1 1 0 Helicase HerA, central domain Atg14 PF10186.9 KPA37920.1 - 9.3 5.2 13.8 12 4.8 13.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 4HBT_3 PF13622.6 KPA37922.1 - 3.7e-48 164.9 0.0 4.2e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KPA37922.1 - 0.00018 21.3 0.0 0.0017 18.2 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA thioesterase DUF4947 PF16305.5 KPA37922.1 - 0.033 14.2 0.2 0.085 12.9 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4947) DUF2680 PF10925.8 KPA37922.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) DUF3659 PF12396.8 KPA37922.1 - 0.2 11.6 0.2 21 5.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) ABC2_membrane PF01061.24 KPA37923.1 - 1.8e-82 275.8 51.4 1.4e-43 148.8 19.0 2.6 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.12 KPA37923.1 - 4.7e-31 106.5 0.0 4.7e-31 106.5 0.0 3.7 4 0 0 4 4 4 1 CDR ABC transporter ABC_tran PF00005.27 KPA37923.1 - 5.8e-26 91.6 0.1 6e-17 62.4 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KPA37923.1 - 5.4e-17 62.2 1.0 1.2e-16 61.1 0.1 2.2 2 0 0 2 2 2 1 ABC-transporter N-terminal DUF4267 PF14087.6 KPA37923.1 - 5.6e-12 45.7 0.4 5.6e-12 45.7 0.4 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4267) ABC2_membrane_3 PF12698.7 KPA37923.1 - 1.8e-11 43.7 34.6 1.8e-09 37.2 8.8 3.2 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.6 KPA37923.1 - 0.00094 18.8 0.0 0.0027 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA37923.1 - 0.0014 19.1 0.1 0.0038 17.6 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KPA37923.1 - 0.0042 17.0 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KPA37923.1 - 0.0062 16.3 0.3 0.029 14.1 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KPA37923.1 - 0.016 15.8 0.0 0.035 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KPA37923.1 - 0.023 14.5 0.0 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KPA37923.1 - 0.035 14.3 0.2 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KPA37923.1 - 0.14 11.6 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Methyltransf_2 PF00891.18 KPA37925.1 - 2.2e-20 72.9 0.0 3.7e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Rrf2 PF02082.20 KPA37925.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Lactamase_B_3 PF13483.6 KPA37926.1 - 0.006 16.5 0.4 0.021 14.7 0.4 1.9 1 1 1 2 2 2 1 Beta-lactamase superfamily domain UMPH-1 PF05822.12 KPA37927.1 - 0.13 11.7 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) F-box_4 PF15966.5 KPA37928.1 - 0.004 17.0 0.2 0.011 15.6 0.2 1.7 1 0 0 1 1 1 1 F-box F-box PF00646.33 KPA37928.1 - 0.0081 16.0 0.1 0.02 14.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain APH PF01636.23 KPA37930.1 - 1.6e-07 31.5 0.1 0.0049 16.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KPA37930.1 - 2.9e-05 23.8 0.0 5.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KPA37930.1 - 0.0021 17.4 0.0 0.0078 15.6 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KPA37930.1 - 0.0081 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.25 KPA37930.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Seadorna_VP7 PF07387.11 KPA37930.1 - 0.066 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF745 PF05335.13 KPA37933.1 - 0.00014 21.7 8.4 0.00017 21.4 8.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Cnn_1N PF07989.11 KPA37933.1 - 0.0041 17.2 5.2 0.0041 17.2 5.2 2.1 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 SirA PF10747.9 KPA37933.1 - 0.0049 17.2 5.8 0.0059 16.9 5.8 1.1 1 0 0 1 1 1 1 Sporulation inhibitor of replication protein SirA ERM PF00769.19 KPA37933.1 - 0.0054 16.6 10.1 0.0058 16.5 10.1 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF812 PF05667.11 KPA37933.1 - 0.0055 15.7 7.5 0.0058 15.6 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Sipho_Gp157 PF05565.11 KPA37933.1 - 0.009 16.0 8.2 0.011 15.7 8.2 1.1 1 0 0 1 1 1 1 Siphovirus Gp157 Peptidase_M18 PF02127.15 KPA37933.1 - 0.013 14.3 2.1 0.017 14.0 2.1 1.1 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) KxDL PF10241.9 KPA37933.1 - 0.014 15.7 5.1 0.02 15.2 4.2 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein PspA_IM30 PF04012.12 KPA37933.1 - 0.019 14.6 12.3 0.022 14.3 12.3 1.1 1 0 0 1 1 1 0 PspA/IM30 family Nsp1_C PF05064.13 KPA37933.1 - 0.023 14.5 7.5 0.028 14.2 7.5 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region DUF489 PF04356.12 KPA37933.1 - 0.026 14.5 3.2 0.03 14.3 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF737 PF05300.11 KPA37933.1 - 0.037 14.4 8.4 0.045 14.1 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF3573 PF12097.8 KPA37933.1 - 0.053 12.3 1.0 0.056 12.3 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ADK PF00406.22 KPA37933.1 - 0.069 13.2 0.5 0.1 12.7 0.5 1.3 1 0 0 1 1 1 0 Adenylate kinase MPS2 PF17060.5 KPA37933.1 - 0.11 11.8 5.0 0.13 11.5 5.0 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 ALMT PF11744.8 KPA37933.1 - 0.11 11.3 1.5 0.13 11.0 1.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Atg14 PF10186.9 KPA37933.1 - 0.15 11.1 5.4 0.16 11.0 5.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 KPA37933.1 - 0.28 10.7 5.3 0.3 10.6 5.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Borrelia_P83 PF05262.11 KPA37933.1 - 0.38 9.2 8.3 0.42 9.0 8.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein NPV_P10 PF05531.12 KPA37933.1 - 0.39 11.2 4.7 2.1 8.9 4.7 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GrpE PF01025.19 KPA37933.1 - 0.56 9.9 9.8 0.64 9.7 9.8 1.2 1 0 0 1 1 1 0 GrpE Pec_lyase_N PF04431.13 KPA37933.1 - 0.76 10.1 6.5 4.1 7.7 0.1 3.1 2 1 1 3 3 3 0 Pectate lyase, N terminus Lge1 PF11488.8 KPA37933.1 - 0.9 9.8 10.3 2.1 8.6 10.3 1.8 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Prefoldin PF02996.17 KPA37933.1 - 0.93 9.4 11.5 0.19 11.6 7.0 1.9 1 1 1 2 2 2 0 Prefoldin subunit CRA PF06589.11 KPA37933.1 - 2.5 8.2 7.5 4.5 7.4 1.7 2.0 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) EMC3_TMCO1 PF01956.16 KPA37933.1 - 5.3 6.7 5.5 6.7 6.4 5.5 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like YtxH PF12732.7 KPA37933.1 - 6.6 7.3 7.2 7.3 7.2 2.1 2.1 1 1 1 2 2 2 0 YtxH-like protein NPHI_C PF08469.10 KPA37934.1 - 0.045 13.7 0.1 0.065 13.2 0.1 1.2 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal LRRNT_2 PF08263.12 KPA37935.1 - 0.24 11.8 2.0 0.29 11.5 0.2 2.1 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Pkinase PF00069.25 KPA37938.1 - 4.3e-39 134.5 0.0 9.1e-39 133.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA37938.1 - 7.6e-20 71.3 0.0 2.8e-19 69.4 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase BRCT PF00533.26 KPA37938.1 - 1.3e-09 38.3 0.2 4.1e-09 36.7 0.2 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KPA37938.1 - 1.7e-06 27.8 0.1 3.4e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain Kinase-like PF14531.6 KPA37938.1 - 0.0045 16.3 0.0 4.5 6.5 0.0 3.1 2 1 1 3 3 3 2 Kinase-like RIO1 PF01163.22 KPA37938.1 - 0.064 12.9 0.3 9.1 5.8 0.0 2.5 1 1 1 2 2 2 0 RIO1 family Methyltransf_23 PF13489.6 KPA37939.1 - 7.6e-16 58.4 0.0 1.2e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA37939.1 - 2.1e-10 41.2 0.0 6.2e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA37939.1 - 1.3e-09 38.6 0.0 2.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA37939.1 - 1.6e-06 28.8 0.0 1.3e-05 25.8 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA37939.1 - 0.0062 16.3 0.0 0.17 11.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA37939.1 - 0.02 14.3 0.0 0.11 11.9 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPA37939.1 - 0.034 13.7 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KPA37939.1 - 0.057 13.2 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KPA37939.1 - 0.058 12.9 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Fungal_trans PF04082.18 KPA37940.1 - 2.4e-11 43.2 0.0 4.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RIC3 PF15361.6 KPA37940.1 - 0.03 14.7 0.4 0.069 13.5 0.4 1.6 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 ketoacyl-synt PF00109.26 KPA37941.1 - 9.6e-71 238.3 0.0 2.1e-70 237.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KPA37941.1 - 6.9e-68 229.1 0.2 1.3e-67 228.1 0.0 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KPA37941.1 - 7.5e-58 196.5 0.1 1.4e-57 195.6 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KPA37941.1 - 3e-57 193.4 0.2 7.3e-57 192.2 0.2 1.7 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KPA37941.1 - 8.1e-31 106.5 0.1 2.5e-30 104.9 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KPA37941.1 - 2.7e-19 69.7 0.0 8.5e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KPA37941.1 - 1.5e-08 34.3 0.0 3.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 KPA37941.1 - 0.00024 21.4 0.3 0.00067 20.0 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KPA37941.1 - 0.00041 20.2 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 KPA37941.1 - 0.0011 18.6 0.1 0.0022 17.6 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KPA37941.1 - 0.0011 18.4 0.2 0.0025 17.2 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KPA37941.1 - 0.0073 16.1 0.7 0.02 14.8 0.7 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pyr_redox_3 PF13738.6 KPA37942.1 - 7.9e-16 58.2 0.0 4.8e-14 52.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPA37942.1 - 2.3e-13 49.4 0.0 1.6e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPA37942.1 - 1.8e-07 30.7 0.0 2.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA37942.1 - 1.2e-05 24.3 0.0 0.059 12.1 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein K_oxygenase PF13434.6 KPA37942.1 - 1.6e-05 24.3 0.0 0.00017 20.8 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPA37942.1 - 0.00016 21.7 0.0 0.014 15.4 0.0 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KPA37942.1 - 0.00097 18.3 0.0 0.0024 17.0 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KPA37942.1 - 0.0044 16.3 0.1 0.014 14.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KPA37942.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPA37942.1 - 0.031 14.8 0.3 1.1 9.8 0.0 3.2 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA37942.1 - 0.033 13.8 0.0 5.3 6.5 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase MFS_1 PF07690.16 KPA37943.1 - 1.1e-34 119.9 58.5 4e-34 118.1 54.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA37943.1 - 1.1e-07 31.1 13.0 1.1e-07 31.1 13.0 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KPA37943.1 - 0.001 17.5 1.2 0.001 17.5 1.2 3.0 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.19 KPA37944.1 - 2.7e-26 92.6 0.2 6.5e-26 91.4 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KPA37944.1 - 3.1e-06 26.5 0.9 0.012 14.7 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KPA37944.1 - 9.6e-06 25.0 2.1 0.044 13.0 0.5 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA37944.1 - 1e-05 25.3 2.5 0.00095 18.8 2.5 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA37944.1 - 1.1e-05 25.5 0.4 2.6e-05 24.3 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPA37944.1 - 3.9e-05 23.0 2.5 0.0093 15.2 0.9 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA37944.1 - 9.2e-05 21.7 0.1 0.00012 21.3 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KPA37944.1 - 0.0082 15.4 0.1 0.023 14.0 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KPA37944.1 - 0.013 15.5 0.7 2.6 8.0 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KPA37944.1 - 0.071 12.2 4.2 0.038 13.1 1.7 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KPA37944.1 - 0.41 11.2 3.2 2.8 8.6 0.7 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF2834 PF11196.8 KPA37945.1 - 0.001 19.4 0.2 0.001 19.4 0.2 3.0 2 1 2 4 4 4 1 Protein of unknown function (DUF2834) Acyl_transf_3 PF01757.22 KPA37946.1 - 1.5e-16 60.4 3.1 1.5e-16 60.4 3.1 1.5 2 0 0 2 2 2 1 Acyltransferase family Amidohydro_1 PF01979.20 KPA37947.1 - 2.8e-65 220.9 0.4 5.4e-65 220.0 0.4 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KPA37947.1 - 1.3e-52 177.3 1.6 1.3e-52 177.3 1.6 2.2 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KPA37947.1 - 4.1e-35 119.7 0.0 7.9e-35 118.8 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KPA37947.1 - 1.7e-34 118.1 0.5 3.4e-34 117.1 0.5 1.5 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KPA37947.1 - 1.2e-10 41.5 0.5 0.00013 21.6 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Fe_dep_repress PF01325.19 KPA37947.1 - 0.28 11.4 1.6 0.83 9.9 0.0 2.5 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain ABC2_membrane PF01061.24 KPA37948.1 - 1.5e-83 279.4 42.4 8.1e-45 152.8 18.4 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KPA37948.1 - 9.4e-39 133.1 0.0 1e-19 71.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KPA37948.1 - 2e-27 94.9 0.8 2.7e-22 78.5 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KPA37948.1 - 2.4e-12 47.3 0.0 7.4e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KPA37948.1 - 1.6e-10 40.6 28.5 3.3e-06 26.4 13.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KPA37948.1 - 7.7e-05 23.1 0.3 0.016 15.6 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KPA37948.1 - 0.00041 20.3 0.6 0.0054 16.6 0.1 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 KPA37948.1 - 0.00059 19.5 0.5 0.088 12.6 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KPA37948.1 - 0.00099 18.7 0.1 0.086 12.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPA37948.1 - 0.0014 18.8 0.2 1.7 8.8 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KPA37948.1 - 0.0019 18.0 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KPA37948.1 - 0.002 18.7 0.0 2.5 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KPA37948.1 - 0.0032 17.8 0.0 0.65 10.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KPA37948.1 - 0.008 16.4 1.4 0.71 10.1 0.4 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KPA37948.1 - 0.014 15.0 1.5 2 8.0 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KPA37948.1 - 0.038 13.9 0.2 2.7 7.9 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KPA37948.1 - 0.052 13.3 0.5 5.2 6.7 0.3 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KPA37948.1 - 0.07 12.5 0.0 0.46 9.9 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 KPA37948.1 - 0.1 13.0 0.0 20 5.6 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_2 PF12679.7 KPA37948.1 - 0.18 11.1 11.0 0.0086 15.4 3.8 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Fungal_trans PF04082.18 KPA37949.1 - 3.7e-17 62.2 0.2 6.8e-17 61.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37949.1 - 3.9e-08 33.3 19.8 3.2e-07 30.4 12.7 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5549 PF17703.1 KPA37949.1 - 4.1 7.0 7.2 0.26 10.9 1.7 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5549) Methyltransf_25 PF13649.6 KPA37950.1 - 9.9e-16 58.2 0.0 1.9e-15 57.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA37950.1 - 2.7e-15 56.8 0.0 4.3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA37950.1 - 5.2e-15 55.4 0.0 6.4e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KPA37950.1 - 5e-10 39.4 0.0 8.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA37950.1 - 1.5e-08 34.7 0.0 1.7e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA37950.1 - 1e-07 32.6 0.0 1.6e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA37950.1 - 0.01 15.4 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KPA37950.1 - 0.014 14.8 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 KPA37950.1 - 0.024 13.7 0.0 0.04 13.0 0.0 1.3 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 KPA37950.1 - 0.069 11.7 0.0 0.081 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase OKR_DC_1_C PF03711.15 KPA37950.1 - 0.1 12.9 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain PCMT PF01135.19 KPA37950.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ank_2 PF12796.7 KPA37951.1 - 7.1e-09 36.1 0.0 1.9e-07 31.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA37951.1 - 1.9e-07 31.2 0.1 2e-06 28.0 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) NACHT PF05729.12 KPA37951.1 - 1.1e-06 28.7 0.0 3.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 KPA37951.1 - 1.8e-05 25.0 0.1 0.004 17.5 0.1 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KPA37951.1 - 4.3e-05 24.0 0.4 0.018 15.6 0.1 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA37951.1 - 0.00018 21.7 0.0 0.0074 16.7 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat AAA_16 PF13191.6 KPA37951.1 - 0.0015 18.9 0.0 0.004 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA37951.1 - 0.0024 18.1 0.1 0.017 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KPA37951.1 - 0.036 13.3 0.4 15 4.7 0.2 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) APC_N_CC PF16689.5 KPA37951.1 - 0.049 13.7 0.2 0.32 11.1 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain AAA_14 PF13173.6 KPA37951.1 - 0.05 13.6 0.0 0.47 10.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KPA37951.1 - 0.067 13.1 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 KPA37951.1 - 0.083 13.0 0.0 0.38 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain GMC_oxred_N PF00732.19 KPA37952.1 - 3.1e-33 115.4 0.0 3.3e-28 98.9 0.0 3.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA37952.1 - 5.7e-33 114.5 0.1 1.1e-32 113.6 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KPA37952.1 - 0.00057 19.2 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA37952.1 - 0.0022 18.2 0.1 0.0078 16.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPA37952.1 - 0.0062 15.6 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPA37952.1 - 0.013 14.6 0.1 0.046 12.8 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KPA37952.1 - 0.093 12.0 0.1 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CytB6-F_Fe-S PF08802.10 KPA37952.1 - 0.14 12.2 0.1 0.52 10.4 0.1 2.0 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit FMO-like PF00743.19 KPA37954.1 - 7.6e-56 189.6 0.0 3.8e-48 164.2 0.0 2.2 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPA37954.1 - 8.8e-11 41.6 0.2 7.8e-05 22.1 0.1 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA37954.1 - 2e-07 30.5 0.0 7.1e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA37954.1 - 5.9e-07 29.6 0.0 1.9e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPA37954.1 - 1.5e-05 25.0 1.3 0.00032 20.7 0.0 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KPA37954.1 - 2.9e-05 23.5 0.0 0.016 14.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 KPA37954.1 - 5.8e-05 22.4 1.8 0.0017 17.5 0.1 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KPA37954.1 - 0.00023 20.9 0.0 0.028 14.0 0.0 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA37954.1 - 0.016 15.8 0.1 0.69 10.5 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA37954.1 - 0.05 12.8 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KPA37954.1 - 0.067 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KPA37954.1 - 0.099 11.3 0.1 0.25 10.0 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 KPA37954.1 - 0.1 12.7 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HET PF06985.11 KPA37955.1 - 2e-26 93.1 4.3 1.2e-25 90.6 4.3 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_28 PF00295.17 KPA37956.1 - 2.7e-114 381.6 24.6 3.1e-114 381.4 24.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2111 PF09884.9 KPA37956.1 - 0.16 12.1 1.6 0.2 11.8 0.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2111) AcetylCoA_hyd_C PF13336.6 KPA37956.1 - 0.87 9.5 3.7 0.76 9.7 0.7 2.2 1 1 1 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_61 PF03443.14 KPA37957.1 - 1.1e-54 185.5 0.0 1.3e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HET PF06985.11 KPA37958.1 - 2e-11 44.5 6.5 4.9e-10 39.9 0.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) IL2RB_N1 PF18707.1 KPA37958.1 - 0.0039 17.7 0.6 0.011 16.2 0.6 1.7 1 0 0 1 1 1 1 Interleukin-2 receptor subunit beta N-terminal domain 1 Hce2 PF14856.6 KPA37959.1 - 0.036 14.4 0.2 0.06 13.6 0.2 1.4 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor CBM64 PF18666.1 KPA37959.1 - 0.088 12.9 0.1 0.34 11.0 0.0 2.0 3 0 0 3 3 3 0 Carbohydrate-binding module 64 Transferase PF02458.15 KPA37961.1 - 0.00027 19.7 0.0 2 7.0 0.0 3.1 3 0 0 3 3 3 3 Transferase family Carn_acyltransf PF00755.20 KPA37962.1 - 6.3e-101 338.8 0.0 2.9e-100 336.6 0.0 2.2 3 0 0 3 3 3 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 KPA37962.1 - 8e-74 248.4 0.3 2.7e-73 246.7 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KPA37962.1 - 4.4e-56 190.7 4.6 7e-56 190.0 4.6 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KPA37962.1 - 7.7e-48 162.8 0.0 2.6e-47 161.1 0.0 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KPA37962.1 - 2.9e-45 154.8 0.0 5.9e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KPA37962.1 - 3.9e-37 126.9 1.5 3.4e-36 123.8 0.1 2.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KPA37962.1 - 2.6e-18 66.6 0.0 1e-17 64.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KPA37962.1 - 5e-17 63.2 0.1 6.1e-14 53.2 0.0 3.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KPA37962.1 - 5.7e-17 62.2 0.2 1.5e-16 60.9 0.2 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KPA37962.1 - 3.8e-13 49.5 0.0 1.7e-12 47.5 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KPA37962.1 - 7.7e-12 45.8 0.3 1.7e-09 38.3 0.0 3.8 3 0 0 3 3 3 1 Methyltransferase domain adh_short PF00106.25 KPA37962.1 - 5.9e-10 38.9 0.1 2.2e-08 33.8 0.0 3.2 3 0 0 3 3 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KPA37962.1 - 1.7e-08 35.0 0.0 8.6e-08 32.7 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA37962.1 - 1.5e-07 31.4 0.0 4.1e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KPA37962.1 - 5.1e-06 26.7 0.1 1.6e-05 25.1 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KPA37962.1 - 8.3e-06 25.7 0.0 3e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA37962.1 - 0.00031 20.1 0.0 0.001 18.5 0.0 1.8 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 KPA37962.1 - 0.0019 18.0 0.1 0.0044 16.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KPA37962.1 - 0.025 13.9 1.3 0.042 13.2 0.0 1.9 2 0 0 2 2 2 0 Thiolase, N-terminal domain SAT PF16073.5 KPA37962.1 - 0.033 13.9 5.3 0.013 15.3 2.2 1.9 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Epimerase PF01370.21 KPA37962.1 - 0.14 11.6 0.0 0.43 10.0 0.0 1.8 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SLATT_fungal PF18142.1 KPA37963.1 - 0.22 11.5 0.6 6.5 6.8 0.0 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Methyltransf_2 PF00891.18 KPA37964.1 - 1.8e-18 66.6 0.0 2.6e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KPA37964.1 - 0.0039 17.2 0.0 0.031 14.3 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain AAA PF00004.29 KPA37965.1 - 1.2e-14 54.8 0.0 2.2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NAD_binding_10 PF13460.6 KPA37966.1 - 5.3e-13 49.3 0.0 7.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KPA37966.1 - 0.004 16.6 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase FMO-like PF00743.19 KPA37966.1 - 0.12 10.8 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Amino_oxidase PF01593.24 KPA37967.1 - 5.7e-12 45.7 0.0 8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA37967.1 - 3.3e-11 43.3 0.0 5.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA37967.1 - 0.00033 20.0 0.0 0.00039 19.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA37967.1 - 0.01 16.4 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA37967.1 - 0.013 14.8 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA37967.1 - 0.014 14.9 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 KPA37967.1 - 0.028 14.1 0.1 0.041 13.5 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KPA37967.1 - 0.029 13.1 0.1 0.039 12.6 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KPA37967.1 - 0.053 12.8 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KPA37967.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding ThiF PF00899.21 KPA37967.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 ThiF family AAL_decarboxy PF03306.13 KPA37968.1 - 1.7e-80 269.5 0.1 1.9e-80 269.3 0.1 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase FAD_binding_4 PF01565.23 KPA37969.1 - 2.5e-23 82.3 1.8 5.5e-23 81.2 1.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPA37969.1 - 3.4e-13 49.5 2.2 6.3e-13 48.6 2.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KPA37969.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding HofP PF10748.9 KPA37969.1 - 0.11 12.1 0.2 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 DNA utilization proteins HofP Hexapep PF00132.24 KPA37970.1 - 1e-14 53.6 15.4 2.6e-09 36.4 0.7 4.2 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KPA37970.1 - 1.6e-12 46.9 16.9 1.1e-09 37.9 0.3 3.7 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KPA37970.1 - 8.1e-05 22.8 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase p450 PF00067.22 KPA37971.1 - 3.9e-42 144.6 0.0 5.4e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PPAK PF02818.15 KPA37971.1 - 0.074 13.2 0.4 0.14 12.3 0.4 1.5 1 0 0 1 1 1 0 PPAK motif FAD_binding_3 PF01494.19 KPA37972.1 - 1.3e-84 284.5 0.0 2.8e-84 283.3 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Phe_hydrox_dim PF07976.12 KPA37972.1 - 4.7e-39 134.1 0.0 9.1e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_oxidored PF12831.7 KPA37972.1 - 0.0001 21.8 0.3 0.0005 19.5 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA37972.1 - 0.00067 19.8 0.1 0.002 18.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA37972.1 - 0.0011 18.6 0.9 0.18 11.3 0.6 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KPA37972.1 - 0.0019 17.5 0.4 0.0043 16.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KPA37972.1 - 0.0026 16.9 0.3 0.012 14.7 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 KPA37972.1 - 0.0051 15.9 0.0 0.029 13.4 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.27 KPA37972.1 - 0.0053 17.3 0.2 0.18 12.4 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA37972.1 - 0.007 15.7 1.3 0.016 14.5 0.3 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPA37972.1 - 0.017 14.0 1.2 0.029 13.2 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 KPA37972.1 - 0.018 14.3 0.8 0.71 9.1 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KPA37972.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA37972.1 - 0.026 13.6 1.0 0.044 12.9 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KPA37972.1 - 0.038 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KPA37972.1 - 0.068 11.9 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein MliC PF09864.9 KPA37972.1 - 0.092 12.7 0.0 5.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme FAD_binding_8 PF08022.12 KPA37973.1 - 3.2e-18 65.8 0.0 6.9e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KPA37973.1 - 1.7e-12 47.5 4.4 3.7e-12 46.5 4.4 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPA37973.1 - 1.9e-11 44.3 0.0 6.2e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain EF-hand_7 PF13499.6 KPA37973.1 - 0.00037 20.9 1.0 0.0009 19.7 1.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KPA37973.1 - 0.0054 16.2 1.7 0.018 14.5 0.7 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KPA37973.1 - 0.057 13.3 0.3 0.35 10.8 1.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 KPA37973.1 - 0.16 12.0 0.6 0.72 9.9 0.6 2.1 2 0 0 2 2 2 0 EF-hand domain Pet100 PF09803.9 KPA37973.1 - 9.4 6.8 6.8 0.75 10.4 0.9 2.2 2 0 0 2 2 2 0 Pet100 Abhydrolase_1 PF00561.20 KPA37974.1 - 1.6e-21 77.1 0.0 2.4e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA37974.1 - 6.4e-19 69.4 0.0 8.2e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA37974.1 - 2.3e-11 43.4 0.0 2e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KPA37974.1 - 1e-06 27.7 0.0 1.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family DUF1057 PF06342.12 KPA37974.1 - 0.0028 16.8 0.0 0.004 16.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase2 PF12740.7 KPA37974.1 - 0.087 11.7 0.1 0.31 9.9 0.0 1.9 3 0 0 3 3 3 0 Chlorophyllase enzyme DUF3176 PF11374.8 KPA37975.1 - 9e-19 67.7 3.1 1.7e-18 66.7 3.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Phage_spike_2 PF18781.1 KPA37975.1 - 0.022 14.7 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Phage spike trimer Abhydrolase_3 PF07859.13 KPA37976.1 - 8.1e-55 185.9 0.1 1.1e-54 185.6 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPA37976.1 - 8.6e-07 28.2 0.1 2.9e-06 26.4 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 KPA37976.1 - 0.0007 18.4 0.0 0.0022 16.7 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KPA37976.1 - 0.0033 16.9 0.1 0.082 12.4 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Glyco_hydro_35 PF01301.19 KPA37977.1 - 1.8e-92 310.4 0.6 3.6e-92 309.4 0.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KPA37977.1 - 1.2e-54 184.8 2.8 2.5e-54 183.8 2.8 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KPA37977.1 - 1e-43 148.5 6.1 1.4e-32 112.6 0.1 3.4 3 1 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KPA37977.1 - 1.2e-24 85.6 0.1 3e-24 84.4 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KPA37977.1 - 5.7e-06 26.0 0.1 1.2e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4982 PF16355.5 KPA37977.1 - 0.095 12.7 0.1 0.31 11.0 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) MFS_1 PF07690.16 KPA37979.1 - 2.7e-28 98.9 24.1 3.1e-27 95.4 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidase PF01425.21 KPA37980.1 - 1.7e-84 284.4 0.0 2.9e-84 283.6 0.0 1.4 1 1 0 1 1 1 1 Amidase UPF0257 PF06788.13 KPA37980.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0257) PTR2 PF00854.21 KPA37981.1 - 3.2e-87 293.0 6.4 5.6e-87 292.1 6.4 1.3 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KPA37981.1 - 1e-05 24.6 22.8 0.00016 20.7 21.6 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Tyrosinase PF00264.20 KPA37982.1 - 1.5e-50 172.6 0.1 2.2e-50 172.0 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box_2 PF09011.10 KPA37982.1 - 0.13 12.9 0.4 0.26 11.9 0.4 1.5 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.19 KPA37982.1 - 0.18 12.2 0.4 0.35 11.3 0.4 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Dioxygenase_C PF00775.21 KPA37983.1 - 8.5e-40 136.1 0.0 1.1e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KPA37983.1 - 8.1e-25 86.5 0.1 1.3e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus SpaA PF17802.1 KPA37983.1 - 0.00074 19.8 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 Prealbumin-like fold domain CarboxypepD_reg PF13620.6 KPA37983.1 - 0.011 15.9 0.0 0.039 14.2 0.0 1.9 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Amidohydro_1 PF01979.20 KPA37985.1 - 1.1e-15 57.8 0.2 2.5e-15 56.6 0.2 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPA37985.1 - 2.2e-07 30.7 5.1 4.8e-06 26.3 0.8 2.6 1 1 0 2 2 2 2 Amidohydrolase family NfeD PF01957.18 KPA37985.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Cyt-b5 PF00173.28 KPA37986.1 - 4e-15 55.7 0.0 5.5e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAA_hydrolase PF01557.18 KPA37987.1 - 4.8e-63 212.8 0.0 7.9e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 KPA37987.1 - 1.2e-20 74.3 0.3 2.8e-13 50.1 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA37987.1 - 2e-17 64.5 0.2 3.2e-17 63.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA37987.1 - 1.2e-16 60.7 0.0 2.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KPA37987.1 - 3e-07 30.5 2.9 0.00046 20.1 0.1 2.6 2 1 1 3 3 3 2 Serine hydrolase Abhydrolase_4 PF08386.10 KPA37987.1 - 9.2e-05 22.5 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_8 PF06259.12 KPA37987.1 - 0.028 14.0 0.8 0.066 12.8 0.2 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase Peptidase_S9 PF00326.21 KPA37987.1 - 0.065 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family LCAT PF02450.15 KPA37987.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Gpr1_Fun34_YaaH PF01184.19 KPA37988.1 - 3.1e-68 229.5 16.3 3.7e-68 229.2 16.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Pyr_redox_2 PF07992.14 KPA37989.1 - 3.5e-19 69.1 0.0 7.2e-19 68.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA37989.1 - 2e-11 44.3 0.0 1e-08 35.6 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KPA37989.1 - 1.8e-08 33.8 4.1 8.6e-08 31.5 0.5 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA37989.1 - 1e-05 25.5 10.4 1.8e-05 24.7 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain K_oxygenase PF13434.6 KPA37989.1 - 0.033 13.3 0.1 0.18 10.9 0.1 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPA37989.1 - 0.047 12.9 0.0 0.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA37989.1 - 0.047 13.3 0.4 8.1 5.9 0.0 3.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase RNase_H2-Ydr279 PF09468.10 KPA37989.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain FAD_binding_3 PF01494.19 KPA37989.1 - 0.097 11.9 0.5 2.8 7.1 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain FA_hydroxylase PF04116.13 KPA37990.1 - 8e-28 97.4 12.6 8e-28 97.4 12.6 1.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Tropomyosin_1 PF12718.7 KPA37991.1 - 0.007 16.5 4.8 0.014 15.6 4.8 1.4 1 0 0 1 1 1 1 Tropomyosin like DUF724 PF05266.14 KPA37991.1 - 0.01 15.7 3.5 0.017 15.0 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4618 PF15397.6 KPA37991.1 - 0.024 14.1 3.1 0.04 13.3 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF3450 PF11932.8 KPA37991.1 - 0.025 13.9 6.5 0.042 13.2 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 KPA37991.1 - 0.044 12.7 2.1 0.063 12.2 2.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Troponin PF00992.20 KPA37991.1 - 0.069 13.5 2.2 0.27 11.5 0.8 2.1 1 1 1 2 2 2 0 Troponin Filament PF00038.21 KPA37991.1 - 0.069 12.7 5.0 0.1 12.1 5.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein BRE1 PF08647.11 KPA37991.1 - 0.086 12.9 5.1 0.23 11.5 5.0 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF2155 PF09923.9 KPA37991.1 - 0.12 12.7 0.5 0.32 11.3 0.5 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) DUF1811 PF08838.10 KPA37991.1 - 0.29 11.4 2.4 1.5 9.1 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1811) TMF_DNA_bd PF12329.8 KPA37991.1 - 0.4 10.7 5.3 1.5 8.9 5.4 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 KPA37991.1 - 1.1 8.4 2.9 1.6 7.9 2.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein FAM76 PF16046.5 KPA37991.1 - 1.2 8.4 3.5 2.3 7.5 3.5 1.4 1 1 0 1 1 1 0 FAM76 protein ABC_tran_CTD PF16326.5 KPA37991.1 - 1.7 8.9 6.8 1.3 9.3 1.1 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain Csm1_N PF18504.1 KPA37991.1 - 4.7 7.6 6.9 42 4.6 4.6 3.0 1 1 1 2 2 2 0 Csm1 N-terminal domain Pkinase PF00069.25 KPA37992.1 - 4.1e-18 65.7 0.0 3e-17 62.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA37992.1 - 1.8e-13 50.4 0.0 3.8e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KPA37992.1 - 0.028 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KPA37992.1 - 0.2 10.9 0.0 0.93 8.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Peptidase_C2 PF00648.21 KPA37995.1 - 3.8e-37 127.9 0.0 1.3e-35 122.8 0.0 2.5 2 1 0 2 2 2 1 Calpain family cysteine protease PGA_cap PF09587.10 KPA37995.1 - 0.64 9.4 4.6 1.3 8.4 4.6 1.5 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap BTK PF00779.19 KPA37995.1 - 4.9 7.1 6.7 1.9 8.4 0.8 3.0 3 0 0 3 3 3 0 BTK motif Fibritin_C PF07921.12 KPA37996.1 - 0.077 13.1 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Fibritin C-terminal region Big_3_5 PF16640.5 KPA37997.1 - 0.091 13.0 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Ank_2 PF12796.7 KPA37999.1 - 2.4e-50 169.0 0.1 7.7e-15 55.3 0.0 5.2 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA37999.1 - 1.5e-39 133.9 1.1 7.3e-10 39.2 0.0 7.6 5 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA37999.1 - 7e-35 118.7 0.3 4.8e-11 42.7 0.0 6.9 2 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA37999.1 - 2e-33 110.7 0.9 0.00072 19.8 0.0 11.0 11 1 1 12 12 12 8 Ankyrin repeat Ank PF00023.30 KPA37999.1 - 1.8e-31 107.2 10.6 1.9e-05 24.9 0.1 10.2 9 1 0 9 9 9 6 Ankyrin repeat CorA PF01544.18 KPA37999.1 - 4.6e-12 45.8 0.1 8.1e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein WD40 PF00400.32 KPA38001.1 - 1.4e-23 82.7 12.2 8.2e-08 32.8 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat NACHT PF05729.12 KPA38001.1 - 4.8e-14 52.6 0.3 2e-13 50.6 0.1 2.0 2 0 0 2 2 2 1 NACHT domain ANAPC4_WD40 PF12894.7 KPA38001.1 - 6.3e-12 45.6 0.1 1.6e-05 25.1 0.0 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain RelA_SpoT PF04607.17 KPA38001.1 - 4.5e-11 43.0 0.0 9.8e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Nup160 PF11715.8 KPA38001.1 - 0.0026 16.5 0.8 0.09 11.4 0.1 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KPA38001.1 - 0.011 14.7 0.5 0.057 12.4 0.2 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KPA38001.1 - 0.012 16.0 0.0 0.067 13.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 KPA38001.1 - 0.059 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain CorA PF01544.18 KPA38002.1 - 0.00049 19.5 0.5 0.00085 18.7 0.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RasGAP_C PF03836.15 KPA38002.1 - 0.13 12.4 1.2 0.15 12.2 0.1 1.7 2 0 0 2 2 2 0 RasGAP C-terminus NAD_binding_10 PF13460.6 KPA38003.1 - 2.1e-32 112.5 0.0 2.7e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPA38003.1 - 3.6e-05 23.4 0.0 7.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KPA38003.1 - 0.0059 16.1 0.0 0.02 14.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KPA38003.1 - 0.088 12.9 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HTH_53 PF18606.1 KPA38003.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain Zn_clus PF00172.18 KPA38004.1 - 3.5e-08 33.4 8.4 7.2e-08 32.4 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA38004.1 - 1.2e-05 24.3 0.1 6.2e-05 22.0 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain KxDL PF10241.9 KPA38004.1 - 0.023 15.0 0.1 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein GST_N PF02798.20 KPA38005.1 - 3.2e-15 56.2 0.0 5.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPA38005.1 - 3.3e-14 52.9 0.1 5.2e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPA38005.1 - 1.1e-12 48.2 0.0 2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPA38005.1 - 2.6e-08 34.0 0.0 4.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPA38005.1 - 9.4e-08 32.0 0.1 1.6e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA38005.1 - 1.8e-07 31.3 0.0 2.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KPA38005.1 - 0.12 13.1 0.0 0.22 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Pectate_lyase PF03211.13 KPA38006.1 - 3.6e-84 281.4 10.0 4.1e-84 281.2 10.0 1.0 1 0 0 1 1 1 1 Pectate lyase Cu-oxidase_3 PF07732.15 KPA38007.1 - 1.6e-38 131.4 0.1 2.9e-37 127.3 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KPA38007.1 - 7.8e-15 55.3 0.0 1.5e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Phosphoesterase PF04185.14 KPA38008.1 - 2e-76 257.5 6.3 2.7e-76 257.1 6.3 1.1 1 0 0 1 1 1 1 Phosphoesterase family Pyr_redox_3 PF13738.6 KPA38009.1 - 2.2e-11 43.6 0.8 8.8e-09 35.0 0.1 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA38009.1 - 7.1e-09 35.3 0.9 2.5e-07 30.2 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA38009.1 - 1.7e-08 34.0 0.1 3.4e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KPA38009.1 - 9.9e-05 20.9 0.1 0.00041 18.9 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.27 KPA38009.1 - 0.0018 18.8 0.1 2.6 8.6 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KPA38009.1 - 0.019 15.6 0.0 1 10.0 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 KPA38010.1 - 4.3e-20 72.0 55.9 6.9e-12 45.0 22.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 KPA38011.1 - 2.2e-42 144.4 0.0 3.2e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPA38011.1 - 6e-11 42.1 0.0 8.3e-11 41.7 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KPA38011.1 - 0.00052 20.5 0.1 0.001 19.6 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.24 KPA38011.1 - 0.025 14.9 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TrkA_N PF02254.18 KPA38011.1 - 0.026 14.8 0.2 0.4 10.9 0.1 2.4 2 1 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 KPA38011.1 - 0.034 14.6 0.0 0.08 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 KPA38011.1 - 0.13 12.4 0.3 0.23 11.6 0.1 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_64 PF16483.5 KPA38012.1 - 1.2e-122 409.7 0.0 1.5e-122 409.5 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Zn_clus PF00172.18 KPA38013.1 - 1.5e-07 31.4 14.8 2.5e-07 30.7 14.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.6 KPA38014.1 - 8e-45 151.0 7.8 2.1e-18 66.4 0.3 5.0 2 2 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KPA38014.1 - 2.8e-43 144.6 14.0 2.2e-09 36.9 0.1 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KPA38014.1 - 3.3e-18 64.2 3.5 0.0027 17.7 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KPA38014.1 - 9.2e-15 54.8 7.7 5.8e-09 35.8 1.7 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 KPA38014.1 - 1.9e-13 49.6 2.0 0.0075 16.0 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KPA38014.1 - 8.6e-13 47.4 3.3 0.0087 16.2 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KPA38014.1 - 6.3e-10 39.4 3.4 0.0043 17.5 0.1 5.0 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KPA38014.1 - 2.3e-09 37.7 0.1 0.046 14.4 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPA38014.1 - 1.4e-07 31.0 12.3 0.38 10.9 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 KPA38014.1 - 5.1e-07 29.7 0.0 0.81 10.5 0.0 5.9 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPA38014.1 - 5.5e-05 23.7 1.0 1.3 10.0 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA38014.1 - 8e-05 22.8 1.1 0.21 11.8 0.4 3.7 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KPA38014.1 - 0.0001 22.4 3.2 2.3 8.8 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 KPA38014.1 - 0.00084 18.6 0.0 0.0087 15.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain TPR_6 PF13174.6 KPA38014.1 - 0.021 15.5 3.8 30 5.5 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 KPA38014.1 - 0.044 14.1 0.0 56 4.3 0.0 4.6 5 0 0 5 5 5 0 PPR repeat TPR_3 PF07720.12 KPA38014.1 - 0.14 12.1 1.0 25 5.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ATG22 PF11700.8 KPA38015.1 - 2.5e-121 405.7 24.7 2e-120 402.7 24.7 1.9 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like Baculo_11_kDa PF06143.11 KPA38016.1 - 0.52 9.9 4.6 1.8 8.2 1.7 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family FtsX PF02687.21 KPA38016.1 - 2.2 8.8 7.0 4.7 7.7 7.0 1.5 1 0 0 1 1 1 0 FtsX-like permease family DUF4519 PF15012.6 KPA38016.1 - 2.3 8.5 4.0 4.9 7.4 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Ank_2 PF12796.7 KPA38019.1 - 8.2e-19 68.0 0.1 8.9e-18 64.7 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 KPA38019.1 - 1.9e-15 56.5 0.0 2.9e-05 24.3 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KPA38019.1 - 9.3e-15 53.3 0.0 0.00011 22.3 0.0 4.8 5 0 0 5 5 4 3 Ankyrin repeat Ank_5 PF13857.6 KPA38019.1 - 1.6e-13 50.6 0.0 1.2e-06 28.6 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPA38019.1 - 9e-12 45.3 0.0 3.4e-07 30.7 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KPA38019.1 - 1.8e-09 37.2 1.3 1.5e-08 34.2 1.3 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 KPA38019.1 - 1.6e-08 35.1 2.9 9.4e-07 29.4 0.0 3.6 3 1 0 4 4 4 1 AAA ATPase domain NACHT PF05729.12 KPA38019.1 - 0.00051 20.0 0.1 0.0046 16.9 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KPA38019.1 - 0.0014 19.1 0.0 0.0044 17.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA38019.1 - 0.0064 16.8 0.0 0.032 14.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain LisH PF08513.11 KPA38019.1 - 0.014 15.3 0.0 0.36 10.9 0.1 2.9 2 0 0 2 2 2 0 LisH KAP_NTPase PF07693.14 KPA38019.1 - 0.094 11.9 0.1 0.46 9.7 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.6 KPA38019.1 - 0.1 12.7 0.2 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain HET PF06985.11 KPA38021.1 - 3.5e-15 56.6 0.0 1.4e-11 44.9 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF2306 PF10067.9 KPA38023.1 - 2.5e-16 60.2 10.3 5.2e-16 59.2 10.3 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) Fungal_trans_2 PF11951.8 KPA38024.1 - 1.7e-08 33.7 0.3 3e-08 32.9 0.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA38024.1 - 6e-08 32.7 6.8 6e-08 32.7 6.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase_3 PF07732.15 KPA38025.1 - 9.1e-37 125.7 1.3 9.1e-37 125.7 1.3 2.2 3 0 0 3 3 3 1 Multicopper oxidase p450 PF00067.22 KPA38025.1 - 1.5e-25 89.9 0.0 2.5e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Cu-oxidase_2 PF07731.14 KPA38025.1 - 6.9e-20 71.2 8.9 3.2e-16 59.3 0.6 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KPA38025.1 - 4.2e-14 53.0 0.0 9.8e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Trypsin_2 PF13365.6 KPA38025.1 - 6.7e-10 40.1 0.0 4.7e-09 37.3 0.0 2.4 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF4982 PF16355.5 KPA38025.1 - 0.16 12.0 0.1 21 5.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4982) Pkinase_fungal PF17667.1 KPA38026.1 - 7.8e-76 255.5 0.0 9.8e-41 139.9 0.0 2.9 2 1 1 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 KPA38026.1 - 0.0019 17.6 0.0 0.0056 16.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KPA38026.1 - 0.011 15.6 0.0 0.59 10.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Abhydrolase_6 PF12697.7 KPA38027.1 - 1e-14 55.7 0.0 1.2e-14 55.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA38027.1 - 7.5e-07 28.7 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA38027.1 - 0.0024 17.6 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 KPA38027.1 - 0.0041 16.7 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.20 KPA38027.1 - 0.0068 16.5 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 KPA38027.1 - 0.059 13.1 0.1 0.21 11.3 0.0 1.9 1 1 1 2 2 2 0 PGAP1-like protein LCAT PF02450.15 KPA38027.1 - 0.17 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DEAD PF00270.29 KPA38028.1 - 6.1e-43 146.6 0.0 1.1e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA38028.1 - 2.5e-22 79.3 0.1 3.5e-21 75.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA38028.1 - 1.8e-07 31.3 0.0 3.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KPA38028.1 - 0.00044 20.5 0.4 0.022 15.0 0.4 2.9 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 KPA38028.1 - 0.0012 18.8 0.0 0.0034 17.3 0.0 1.8 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.6 KPA38028.1 - 0.0062 16.3 0.0 0.02 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain RhlB PF12300.8 KPA38028.1 - 0.046 13.9 2.0 0.11 12.6 2.0 1.7 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Herpes_UL95 PF03038.14 KPA38028.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 UL95 family Nnf1 PF03980.14 KPA38029.1 - 0.041 14.3 0.3 0.11 12.9 0.3 1.7 1 1 0 1 1 1 0 Nnf1 adh_short PF00106.25 KPA38031.1 - 1e-28 100.1 0.0 2.1e-28 99.1 0.0 1.5 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA38031.1 - 5.5e-20 71.9 0.0 1.1e-19 70.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA38031.1 - 0.027 14.4 0.5 0.17 11.7 0.5 2.2 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 KPA38031.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 KPA38032.1 - 1.9e-63 214.8 0.0 2.6e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 bZIP_1 PF00170.21 KPA38034.1 - 0.4 10.8 3.3 0.61 10.2 3.3 1.2 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KPA38034.1 - 0.59 10.3 2.7 0.91 9.7 2.7 1.2 1 0 0 1 1 1 0 Basic region leucine zipper FAD_syn PF06574.12 KPA38035.1 - 0.078 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase DUF1289 PF06945.13 KPA38036.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) bZIP_2 PF07716.15 KPA38037.1 - 6.2e-13 48.6 11.2 1.1e-12 47.8 11.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper LCD1 PF09798.9 KPA38037.1 - 0.0027 16.3 0.8 0.0027 16.3 0.8 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein bZIP_1 PF00170.21 KPA38037.1 - 0.0077 16.3 11.9 0.018 15.1 11.9 1.6 1 1 0 1 1 1 1 bZIP transcription factor GIT_CC PF16559.5 KPA38037.1 - 0.038 13.8 2.1 0.082 12.8 2.1 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.18 KPA38037.1 - 0.058 13.7 0.3 0.13 12.6 0.3 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 KPA38037.1 - 0.065 13.1 0.7 0.065 13.1 0.7 1.9 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region XhlA PF10779.9 KPA38037.1 - 0.12 12.6 5.2 0.063 13.5 2.6 1.8 2 0 0 2 2 2 0 Haemolysin XhlA ATG16 PF08614.11 KPA38037.1 - 0.23 11.7 12.6 0.085 13.1 9.5 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CENP-N PF05238.13 KPA38038.1 - 5.4e-127 424.5 0.0 6.4e-127 424.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like TatD_DNase PF01026.21 KPA38039.1 - 4.9e-49 167.0 0.1 1.2e-48 165.7 0.1 1.6 1 1 0 1 1 1 1 TatD related DNase Ribonuc_red_lgC PF02867.15 KPA38040.1 - 4.7e-194 645.8 0.0 6.2e-194 645.4 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KPA38040.1 - 1.9e-22 79.0 0.0 7.7e-22 77.1 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KPA38040.1 - 1.2e-16 61.0 0.0 2.4e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 ATP cone domain gag_pre-integrs PF13976.6 KPA38041.1 - 3.2e-10 39.7 0.0 1.1e-09 37.9 0.0 2.0 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 KPA38041.1 - 0.0089 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Sugar_tr PF00083.24 KPA38043.1 - 3.6e-54 184.3 12.3 5.1e-54 183.8 12.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38043.1 - 1e-26 93.7 21.6 1.4e-26 93.2 21.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KPA38043.1 - 6.8e-05 21.3 0.9 6.8e-05 21.3 0.9 2.5 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family zf-C2H2_4 PF13894.6 KPA38043.1 - 0.011 16.5 3.4 0.011 16.5 3.4 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KPA38043.1 - 0.066 13.9 0.1 0.066 13.9 0.1 1.9 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats MFS_3 PF05977.13 KPA38043.1 - 0.14 10.5 5.0 0.23 9.8 5.0 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector DUF1772 PF08592.11 KPA38043.1 - 0.28 11.5 1.9 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) FAM199X PF15814.5 KPA38043.1 - 0.62 9.1 4.8 5.2 6.0 4.7 2.0 2 0 0 2 2 2 0 Protein family FAM199X Trp_oprn_chp PF09534.10 KPA38043.1 - 0.66 9.8 8.3 2.4 7.9 0.5 2.8 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Metallophos PF00149.28 KPA38044.1 - 9e-09 36.1 0.0 3.7e-08 34.1 0.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPA38044.1 - 4.3e-05 23.8 0.0 0.00017 21.8 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Galactosyl_T PF01762.21 KPA38045.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Galactosyltransferase ADH_N_2 PF16884.5 KPA38047.1 - 1.5e-23 82.8 0.0 2.2e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KPA38047.1 - 3.9e-23 81.8 0.0 6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA38047.1 - 9.3e-07 30.0 0.0 1.5e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CP2 PF04516.15 KPA38048.1 - 8.6e-25 87.4 0.4 1.4e-24 86.7 0.4 1.3 1 0 0 1 1 1 1 CP2 transcription factor HATPase_c PF02518.26 KPA38049.1 - 3.8e-21 75.7 0.0 8.4e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPA38049.1 - 1.5e-16 60.6 0.1 5e-15 55.6 0.1 2.7 1 1 0 1 1 1 1 Response regulator receiver domain DLH PF01738.18 KPA38049.1 - 1.8e-16 60.4 0.2 3.1e-16 59.6 0.2 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family PAS_9 PF13426.7 KPA38049.1 - 2.9e-12 46.8 0.0 0.00021 21.5 0.0 4.2 3 0 0 3 3 3 2 PAS domain HisKA PF00512.25 KPA38049.1 - 2.6e-09 37.0 0.0 1.3e-08 34.7 0.0 2.4 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KPA38049.1 - 5.2e-09 36.3 0.1 0.0001 22.5 0.0 3.7 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.10 KPA38049.1 - 1.3e-08 35.1 0.1 0.0018 18.5 0.0 5.4 5 1 0 5 5 5 2 PAS fold PAS PF00989.25 KPA38049.1 - 1.4e-08 34.8 0.0 6e-06 26.2 0.0 4.0 4 0 0 4 4 4 1 PAS fold PAS_8 PF13188.7 KPA38049.1 - 1.5e-08 34.5 0.0 6.9e-06 26.0 0.0 4.0 4 0 0 4 4 4 1 PAS domain PAS_7 PF12860.7 KPA38049.1 - 0.022 14.9 0.1 0.17 12.0 0.0 2.6 2 1 0 2 2 2 0 PAS fold GAF_2 PF13185.6 KPA38049.1 - 0.022 15.0 0.0 0.069 13.4 0.0 1.8 1 0 0 1 1 1 0 GAF domain ACPS PF01648.20 KPA38050.1 - 7.4e-10 39.0 0.0 1.4e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily RNase_H2_suC PF08615.11 KPA38050.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Peptidase_A22B PF04258.13 KPA38051.1 - 1.4e-59 202.0 3.3 5.2e-39 134.5 0.7 2.2 2 0 0 2 2 2 2 Signal peptide peptidase Presenilin PF01080.17 KPA38051.1 - 7.9 5.1 8.7 0.17 10.6 0.5 2.3 2 1 0 2 2 2 0 Presenilin Pro_isomerase PF00160.21 KPA38052.1 - 1.5e-52 178.0 0.0 1.8e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2732 PF10809.8 KPA38053.1 - 0.0037 17.1 0.5 0.0098 15.7 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2732) DUF3246 PF11596.8 KPA38053.1 - 0.037 13.5 1.2 0.061 12.8 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) zf_UBZ PF18439.1 KPA38053.1 - 0.13 11.8 1.7 1.9 8.2 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 KPA38053.1 - 1.6 8.4 7.5 0.16 11.6 3.1 1.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Apt1 PF10351.9 KPA38053.1 - 2.6 6.8 12.0 0.65 8.8 0.1 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Acetyltransf_1 PF00583.25 KPA38054.1 - 0.03 14.6 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Hexokinase_1 PF00349.21 KPA38055.1 - 9.3e-76 254.2 0.0 1.3e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KPA38055.1 - 7.8e-75 251.4 0.0 1e-74 251.0 0.0 1.1 1 0 0 1 1 1 1 Hexokinase HHH_5 PF14520.6 KPA38055.1 - 0.1 13.2 0.1 0.29 11.8 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain YhdB PF14148.6 KPA38055.1 - 0.11 12.6 0.0 4.7 7.4 0.1 2.4 2 0 0 2 2 2 0 YhdB-like protein RICTOR_N PF14664.6 KPA38056.1 - 1.4e-136 455.4 0.0 3.9e-136 453.9 0.0 1.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KPA38056.1 - 1.8e-40 136.9 0.1 1.5e-37 127.5 0.0 4.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KPA38056.1 - 1e-37 128.8 0.1 9.7e-36 122.5 0.0 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KPA38056.1 - 9.1e-31 105.9 0.2 6.5e-29 100.0 0.1 3.6 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KPA38056.1 - 7.2e-15 54.9 9.1 1.8e-14 53.6 9.1 1.7 1 0 0 1 1 1 1 Hr1 repeat HEAT_EZ PF13513.6 KPA38056.1 - 0.035 14.6 0.6 26 5.4 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat Uds1 PF15456.6 KPA38056.1 - 0.068 13.3 6.6 0.17 12.0 6.6 1.6 1 0 0 1 1 1 0 Up-regulated During Septation DUF2203 PF09969.9 KPA38056.1 - 3 8.6 6.5 7.6 7.3 6.5 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Tex_N PF09371.10 KPA38056.1 - 6.1 6.5 9.2 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Tex-like protein N-terminal domain Phos_pyr_kin PF08543.12 KPA38057.1 - 1.1e-84 283.7 2.0 1.7e-84 283.1 2.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KPA38057.1 - 3e-52 177.5 0.4 4.9e-52 176.8 0.4 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KPA38057.1 - 9e-08 31.8 0.3 4.8e-07 29.4 0.3 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 KPA38057.1 - 0.029 13.8 3.9 0.37 10.1 0.1 2.5 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family HHH_4 PF14490.6 KPA38057.1 - 0.14 12.1 0.4 48 4.0 0.0 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix containing domain Nop14 PF04147.12 KPA38058.1 - 1.8 6.7 6.3 2.3 6.3 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family Pyr_redox_2 PF07992.14 KPA38059.1 - 1e-52 179.3 0.0 1.3e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA38059.1 - 1.8e-12 47.6 0.1 1.1e-10 42.0 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA38059.1 - 0.00052 19.4 0.1 0.15 11.3 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DHR10 PF18595.1 KPA38059.1 - 0.015 15.3 0.8 0.031 14.3 0.8 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain EcoR124_C PF12008.8 KPA38059.1 - 0.16 11.6 0.6 0.27 10.8 0.0 1.5 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal XhlA PF10779.9 KPA38059.1 - 7.1 6.9 7.5 4.8 7.5 2.4 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Aminotran_5 PF00266.19 KPA38060.1 - 1.1e-08 34.4 0.0 1.3e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KPA38060.1 - 0.0012 17.5 0.0 0.0017 17.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KPA38060.1 - 0.0078 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family EIAV_Rev PF11129.8 KPA38060.1 - 0.0096 16.1 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 1 Rev protein of equine infectious anaemia virus DEAD PF00270.29 KPA38061.1 - 3.3e-49 167.0 0.0 3.6e-48 163.6 0.0 2.2 1 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA38061.1 - 1.2e-31 109.3 0.1 4e-31 107.6 0.1 1.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA38061.1 - 3.3e-05 24.0 0.0 0.00024 21.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KPA38061.1 - 0.0018 18.7 0.0 2 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain UTP25 PF06862.12 KPA38061.1 - 0.0052 15.6 0.0 0.12 11.2 0.0 2.2 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_C_2 PF13307.6 KPA38061.1 - 0.014 15.6 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain NmrA PF05368.13 KPA38064.1 - 2.1e-15 56.9 0.0 2.9e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA38064.1 - 2e-09 37.6 0.2 8.1e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KPA38064.1 - 7.8e-05 22.2 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KPA38064.1 - 0.0095 16.5 0.4 0.1 13.2 0.2 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KPA38064.1 - 0.021 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KPA38064.1 - 0.025 15.0 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KPA38064.1 - 0.17 12.0 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KPA38065.1 - 3.8e-35 121.1 0.0 5e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA38065.1 - 6.5e-26 91.3 0.0 8.4e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 KPA38065.1 - 0.00022 21.5 0.0 0.02 15.2 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain KR PF08659.10 KPA38065.1 - 0.00027 20.9 0.1 0.001 19.0 0.1 1.9 1 1 0 1 1 1 1 KR domain ThiF PF00899.21 KPA38065.1 - 0.00076 18.9 0.1 0.0012 18.3 0.1 1.2 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 KPA38065.1 - 0.00091 18.6 0.0 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KPA38065.1 - 0.0011 19.0 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Polysacc_synt_2 PF02719.15 KPA38065.1 - 0.0064 15.7 0.0 0.0071 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KPA38065.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 KPA38065.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) UDPG_MGDP_dh_N PF03721.14 KPA38065.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Epimerase PF01370.21 KPA38065.1 - 0.037 13.5 0.1 0.061 12.8 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KPA38065.1 - 0.04 13.9 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase LpxI_N PF17930.1 KPA38065.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 LpxI N-terminal domain HET PF06985.11 KPA38066.1 - 6.3e-22 78.5 0.3 1.1e-21 77.7 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4231 PF14015.6 KPA38069.1 - 1.1 9.8 4.1 1.9 9.0 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) MFS_1 PF07690.16 KPA38070.1 - 6.7e-35 120.6 48.7 2.8e-34 118.6 44.5 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily GATase PF00117.28 KPA38073.1 - 7.3e-11 42.2 0.0 1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KPA38073.1 - 0.0013 18.6 0.2 0.0035 17.1 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 HTS PF04204.16 KPA38073.1 - 0.0073 15.3 0.0 0.017 14.1 0.0 1.5 1 1 0 1 1 1 1 Homoserine O-succinyltransferase CtnDOT_TraJ PF07863.11 KPA38073.1 - 0.083 13.6 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon AMP-binding PF00501.28 KPA38074.1 - 3.3e-134 447.7 0.0 2e-72 244.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KPA38074.1 - 1.8e-83 280.7 0.0 7.3e-43 146.9 0.0 4.1 4 1 0 4 4 4 3 Condensation domain PP-binding PF00550.25 KPA38074.1 - 2.1e-16 60.0 0.1 4.9e-08 33.2 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KPA38074.1 - 1.2e-09 39.0 0.1 2.5e-05 25.2 0.0 3.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KPA38074.1 - 0.086 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Transferase family Asn_synthase PF00733.21 KPA38075.1 - 2.2e-67 228.2 0.0 3e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KPA38075.1 - 1.5e-35 121.8 0.0 4.7e-35 120.2 0.0 1.9 3 0 0 3 3 3 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KPA38075.1 - 2.5e-30 105.4 0.0 7.3e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KPA38075.1 - 5.1e-05 22.8 0.0 9.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.16 KPA38075.1 - 0.049 12.4 0.0 0.084 11.6 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Velvet PF11754.8 KPA38076.1 - 8.9e-54 183.1 7.0 8.2e-35 120.9 0.1 2.9 2 1 1 3 3 3 2 Velvet factor Phage_fiber PF03335.13 KPA38076.1 - 3 8.2 6.6 2.2 8.7 0.7 3.2 2 0 0 2 2 2 0 Phage tail fibre repeat DUF3481 PF11980.8 KPA38077.1 - 0.076 12.7 0.2 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein PSI_integrin PF17205.3 KPA38077.1 - 0.23 11.2 2.3 0.46 10.3 0.0 2.5 3 0 0 3 3 3 0 Integrin plexin domain ABC_membrane PF00664.23 KPA38078.1 - 5e-93 311.7 37.3 1.5e-48 165.8 16.2 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KPA38078.1 - 4.9e-68 227.9 0.0 7e-33 114.0 0.0 3.1 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPA38078.1 - 4.4e-14 52.4 0.0 4.6e-05 23.0 0.0 3.5 1 1 2 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KPA38078.1 - 8.7e-08 32.3 0.3 0.0079 16.1 0.1 3.5 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KPA38078.1 - 4.6e-07 29.5 1.2 0.0033 17.1 0.2 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KPA38078.1 - 2.7e-06 26.5 2.4 0.045 12.5 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 KPA38078.1 - 7.8e-06 26.2 0.9 0.45 10.8 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KPA38078.1 - 4.5e-05 23.4 0.7 0.27 11.0 0.0 3.8 4 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KPA38078.1 - 5.6e-05 22.8 0.1 0.14 11.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KPA38078.1 - 7.2e-05 23.2 3.7 0.21 12.0 0.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KPA38078.1 - 0.00022 21.1 0.0 0.3 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KPA38078.1 - 0.003 17.3 2.3 1.4 8.6 0.0 3.7 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.12 KPA38078.1 - 0.0046 16.2 0.0 2.7 7.2 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 KPA38078.1 - 0.0059 16.9 0.2 0.83 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPA38078.1 - 0.0061 16.7 0.0 2.2 8.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPA38078.1 - 0.013 16.0 0.0 8.2 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KPA38078.1 - 0.017 14.3 0.0 4.6 6.3 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit SRP54 PF00448.22 KPA38078.1 - 0.023 14.3 0.6 1.9 8.1 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KPA38078.1 - 0.027 14.5 0.2 7.2 6.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KPA38078.1 - 0.035 14.2 3.4 2.5 8.1 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain Rad17 PF03215.15 KPA38078.1 - 0.038 13.9 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 KPA38078.1 - 0.044 14.3 3.4 0.74 10.3 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KPA38078.1 - 0.056 12.9 0.0 9.6 5.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KPA38078.1 - 0.072 13.5 0.1 13 6.2 0.0 3.4 3 0 0 3 3 2 0 RNA helicase PRK PF00485.18 KPA38078.1 - 0.079 12.7 0.0 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 KPA38078.1 - 0.099 12.4 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cu_bind_CorA PF18252.1 KPA38078.1 - 0.11 12.1 0.0 0.37 10.4 0.0 1.8 1 0 0 1 1 1 0 Copper(I)-binding protein CorA SbcCD_C PF13558.6 KPA38078.1 - 0.19 12.0 7.7 5 7.4 0.2 3.8 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit BLF1 PF17752.1 KPA38079.1 - 0.082 12.2 0.1 0.22 10.8 0.1 1.6 1 0 0 1 1 1 0 Burkholderia lethal factor 1 zf-BED PF02892.15 KPA38079.1 - 0.13 12.3 0.7 0.34 11.0 0.7 1.8 1 0 0 1 1 1 0 BED zinc finger PspB PF06667.12 KPA38080.1 - 0.044 13.8 0.1 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Phage shock protein B LPG_synthase_TM PF03706.13 KPA38080.1 - 0.055 13.0 6.8 1.1 8.7 3.0 2.0 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region SNF PF00209.18 KPA38081.1 - 2.2e-80 270.9 38.1 1.5e-48 165.8 14.6 3.0 3 0 0 3 3 3 3 Sodium:neurotransmitter symporter family TPR_2 PF07719.17 KPA38082.1 - 1.1e-08 34.6 1.7 4.1e-05 23.4 0.3 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KPA38082.1 - 1.3e-07 31.1 3.2 0.00085 19.0 0.2 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPA38082.1 - 4.3e-06 26.5 2.4 0.034 14.4 0.4 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KPA38082.1 - 0.00012 21.7 1.5 0.0039 16.8 0.1 2.5 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 KPA38082.1 - 0.00019 21.6 3.6 0.058 13.8 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat SesA PF17107.5 KPA38082.1 - 0.00032 20.9 0.1 0.00076 19.7 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_14 PF13428.6 KPA38082.1 - 0.013 16.3 0.4 44 5.3 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPA38082.1 - 0.031 14.9 3.0 5.3 7.8 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Paf67 PF10255.9 KPA38082.1 - 0.052 12.5 0.3 0.17 10.8 0.2 1.8 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 TPR_12 PF13424.6 KPA38082.1 - 0.12 12.7 0.8 5.2 7.4 0.8 2.7 1 1 0 1 1 1 0 Tetratricopeptide repeat Acyl-CoA_dh_1 PF00441.24 KPA38083.1 - 7.2e-23 81.5 0.5 7.2e-23 81.5 0.5 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPA38083.1 - 5.8e-08 32.8 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPA38083.1 - 2.2e-07 31.6 0.1 4.4e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KPA38083.1 - 1.2e-05 25.6 1.6 1.2e-05 25.6 1.6 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3663 PF12404.8 KPA38084.1 - 0.0017 18.3 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase 3Beta_HSD PF01073.19 KPA38085.1 - 1.5e-43 148.8 0.0 1.8e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPA38085.1 - 2.1e-32 112.5 0.0 2.7e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPA38085.1 - 3e-19 69.2 0.8 1.2e-13 50.9 0.1 2.2 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KPA38085.1 - 6.6e-19 68.5 0.0 9.3e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KPA38085.1 - 3.9e-15 55.7 0.0 4.5e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KPA38085.1 - 5.8e-12 45.9 0.2 1.6e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KPA38085.1 - 9.8e-12 44.6 0.0 5e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KPA38085.1 - 7.7e-09 35.7 0.1 4.2e-08 33.3 0.1 2.0 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KPA38085.1 - 7.2e-05 22.5 0.0 9.6e-05 22.0 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KPA38085.1 - 0.00064 19.2 0.0 0.0019 17.7 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.20 KPA38085.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KPA38086.1 - 1.1e-20 73.9 0.0 8.5e-18 64.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA38086.1 - 3.1e-13 49.8 0.1 1.4e-11 44.4 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA38086.1 - 3.6e-10 40.0 0.2 6e-10 39.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA38086.1 - 6.2e-08 32.4 0.0 7.8e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KPA38086.1 - 0.013 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KPA38086.1 - 0.013 14.6 0.0 0.15 11.2 0.0 2.1 1 1 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.20 KPA38086.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Response_reg PF00072.24 KPA38087.1 - 1.1e-07 32.0 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GFA PF04828.14 KPA38088.1 - 1.3e-18 67.1 0.8 1.8e-18 66.6 0.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme KH_9 PF17904.1 KPA38088.1 - 0.065 13.6 0.0 5.2 7.5 0.0 2.2 2 0 0 2 2 2 0 FMRP KH0 domain Fungal_trans PF04082.18 KPA38089.1 - 3.5e-11 42.6 0.8 5.5e-11 42.0 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA38089.1 - 4.3e-08 33.2 11.4 1.7e-07 31.2 11.4 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF932 PF06067.11 KPA38089.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Flagellin_C PF00700.21 KPA38090.1 - 0.036 14.4 2.4 0.045 14.1 0.3 2.2 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF2347 PF09804.9 KPA38090.1 - 0.93 9.0 4.2 3.4 7.2 1.7 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) FapA PF03961.13 KPA38090.1 - 1.3 7.5 8.4 1.7 7.1 5.2 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A RRP36 PF06102.12 KPA38090.1 - 1.7 8.6 10.8 0.24 11.4 6.3 1.8 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 DUF1664 PF07889.12 KPA38090.1 - 2.4 8.2 10.3 18 5.4 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) CALM_bind PF16025.5 KPA38091.1 - 0.27 11.7 4.7 0.62 10.6 4.7 1.6 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Methyltransf_3 PF01596.17 KPA38092.1 - 2.1e-13 49.9 0.0 3.8e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KPA38092.1 - 4.5e-13 50.1 0.0 7.3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KPA38092.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase AhpC-TSA_2 PF13911.6 KPA38094.1 - 6.1e-07 29.6 0.1 1e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KPA38094.1 - 0.0098 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin SpoVS PF04232.12 KPA38094.1 - 0.059 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) OPT PF03169.15 KPA38096.1 - 1.3e-167 559.1 44.9 1.5e-167 559.0 44.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3382 PF11862.8 KPA38096.1 - 0.043 14.1 2.1 0.45 10.8 0.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DUF5381 PF17353.2 KPA38096.1 - 2.5 7.8 4.9 8.2 6.1 4.9 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5381) Abhydrolase_3 PF07859.13 KPA38097.1 - 6.6e-21 75.1 0.0 8.7e-18 64.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA38097.1 - 2.9e-05 24.8 0.2 4.2e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPA38097.1 - 4.3e-05 23.1 0.0 0.18 11.3 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KPA38097.1 - 0.0064 15.4 0.2 0.013 14.4 0.2 1.4 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 KPA38097.1 - 0.18 11.4 0.0 0.44 10.1 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 KPA38097.1 - 0.19 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Glyco_hydro_31 PF01055.26 KPA38098.1 - 3.3e-148 494.5 2.2 4.3e-148 494.2 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KPA38098.1 - 3.2e-36 124.0 0.0 6.9e-36 123.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KPA38098.1 - 2e-13 50.4 1.1 6e-13 48.9 1.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like HIG_1_N PF04588.13 KPA38099.1 - 1.4e-05 25.3 1.1 1.4e-05 25.3 1.1 2.5 2 1 1 3 3 3 1 Hypoxia induced protein conserved region NmrA PF05368.13 KPA38100.1 - 6.9e-23 81.4 0.3 8.1e-23 81.2 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA38100.1 - 1.2e-18 67.7 0.0 1.8e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPA38100.1 - 8e-07 29.4 2.7 2.9e-05 24.4 0.4 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPA38100.1 - 9.3e-07 28.5 0.4 1.8e-06 27.6 0.3 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA38100.1 - 1.2e-05 24.5 1.6 1.8e-05 23.9 1.6 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KPA38100.1 - 0.00059 19.9 0.2 0.001 19.1 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 KPA38100.1 - 0.0023 17.1 0.1 0.0036 16.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 KPA38100.1 - 0.0027 17.6 1.5 0.006 16.5 1.5 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KPA38100.1 - 0.0046 17.1 0.5 0.01 16.0 0.2 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 KPA38100.1 - 0.0065 16.0 1.2 0.013 14.9 0.4 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPA38100.1 - 0.011 15.7 0.1 0.023 14.6 0.1 1.5 1 1 0 1 1 1 0 KR domain DFP PF04127.15 KPA38100.1 - 0.012 15.5 0.7 0.023 14.5 0.7 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Semialdhyde_dh PF01118.24 KPA38100.1 - 0.02 15.3 0.4 0.053 13.9 0.4 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KPA38100.1 - 0.026 13.9 0.2 0.05 13.0 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Glyco_trans_4_2 PF13477.6 KPA38100.1 - 0.068 13.2 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like DapB_N PF01113.20 KPA38100.1 - 0.47 10.6 4.3 0.28 11.3 1.5 2.1 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Sulfatase PF00884.23 KPA38101.1 - 3.2e-19 69.5 1.4 5.1e-19 68.8 1.4 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPA38101.1 - 2.6e-05 24.0 0.1 4.5e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KPA38101.1 - 4.5e-05 22.3 0.2 7.3e-05 21.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Virul_fac_BrkB PF03631.15 KPA38101.1 - 0.49 10.0 12.1 0.4 10.2 4.1 2.9 2 1 0 3 3 3 0 Virulence factor BrkB FtsX PF02687.21 KPA38101.1 - 2.4 8.7 7.9 2.7 8.5 3.7 2.7 1 1 2 3 3 3 0 FtsX-like permease family Abhydrolase_1 PF00561.20 KPA38102.1 - 7.3e-09 35.6 0.6 7.6e-06 25.8 0.1 2.8 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA38102.1 - 2.3e-08 34.9 0.0 9.4e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA38102.1 - 0.00051 19.4 0.0 0.0014 17.9 0.0 1.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KPA38102.1 - 0.0074 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 KPA38102.1 - 0.014 15.1 0.0 0.058 13.1 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein DUF4515 PF14988.6 KPA38103.1 - 0.017 15.0 3.8 0.025 14.4 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Pedibin PF08182.11 KPA38103.1 - 0.036 13.9 3.0 0.11 12.3 3.0 1.8 1 0 0 1 1 1 0 Pedibin/Hym-346 family DLH PF01738.18 KPA38104.1 - 5e-08 32.8 0.0 9.6e-07 28.6 0.0 2.4 3 0 0 3 3 3 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KPA38104.1 - 3.2e-07 30.4 0.0 4.2e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA38104.1 - 1e-05 25.1 0.0 2.3e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KPA38104.1 - 0.00044 20.0 0.1 0.049 13.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 KPA38104.1 - 0.0068 16.1 0.0 0.0094 15.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF829 PF05705.14 KPA38104.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Hydrolase_4 PF12146.8 KPA38104.1 - 0.054 12.8 0.0 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KPA38104.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein LIP PF03583.14 KPA38104.1 - 0.14 11.4 0.0 0.8 9.0 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase SCNM1_acidic PF15805.5 KPA38105.1 - 1.1 9.1 3.4 4.6 7.0 0.6 2.2 1 1 1 2 2 2 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 NYN PF01936.18 KPA38106.1 - 1e-11 45.5 0.0 1.6e-11 44.9 0.0 1.4 1 1 0 1 1 1 1 NYN domain NAD_binding_10 PF13460.6 KPA38107.1 - 1.1e-24 87.4 0.0 1.2e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPA38107.1 - 1e-06 28.5 0.1 2.8e-06 27.1 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KPA38107.1 - 3.5e-06 26.6 0.0 8.6e-06 25.4 0.0 1.6 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA38107.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FAD_binding_3 PF01494.19 KPA38108.1 - 3.6e-31 108.7 0.0 8.6e-31 107.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA38108.1 - 7.4e-08 32.3 0.6 0.0046 16.6 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA38108.1 - 2.5e-05 23.7 0.2 0.047 12.9 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA38108.1 - 7.3e-05 22.9 0.3 0.00017 21.8 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KPA38108.1 - 0.00049 19.2 0.0 0.025 13.6 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.24 KPA38108.1 - 0.0014 17.8 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KPA38108.1 - 0.0017 18.9 0.0 0.3 11.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPA38108.1 - 0.0069 15.3 0.0 2.4 6.9 0.0 2.9 3 0 0 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.12 KPA38108.1 - 0.01 14.9 0.0 0.22 10.5 0.0 2.8 3 1 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.14 KPA38108.1 - 0.019 13.7 0.0 0.82 8.3 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein FMO-like PF00743.19 KPA38108.1 - 0.077 11.4 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KPA38108.1 - 0.14 12.1 0.2 0.64 10.0 0.1 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF1593 PF07632.11 KPA38110.1 - 2.3e-77 259.9 0.0 3.2e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) Amidohydro_1 PF01979.20 KPA38110.1 - 6.5e-13 48.7 0.0 1.4e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPA38110.1 - 0.00031 20.3 0.3 0.062 12.8 0.1 3.0 3 0 0 3 3 3 2 Amidohydrolase family REJ PF02010.15 KPA38110.1 - 0.021 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 REJ domain PGA_cap PF09587.10 KPA38110.1 - 0.082 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Methyltransf_25 PF13649.6 KPA38111.1 - 2.2e-07 31.5 0.0 6.1e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA38111.1 - 1.4e-06 28.1 0.1 9.3e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA38111.1 - 3.2e-06 27.8 0.0 1.8e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA38111.1 - 3.9e-06 27.4 0.0 8.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA38111.1 - 7e-06 26.0 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding PF00501.28 KPA38111.1 - 2.7e-05 22.9 0.0 4.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NodS PF05401.11 KPA38111.1 - 0.0021 17.7 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 KPA38111.1 - 0.027 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase NAD_binding_4 PF07993.12 KPA38112.1 - 1.2e-15 57.4 1.9 1.2e-14 54.2 0.1 2.2 1 1 1 2 2 2 1 Male sterility protein PP-binding PF00550.25 KPA38112.1 - 9.4e-07 29.1 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KPA38112.1 - 3.2e-05 23.5 0.8 0.00096 18.7 0.1 2.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA38112.1 - 0.00024 20.2 2.2 0.00098 18.2 0.2 2.1 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KPA38112.1 - 0.19 10.8 4.4 0.43 9.7 1.6 2.6 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein DUF4520 PF15016.6 KPA38113.1 - 0.0095 16.0 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4520) Sugar_tr PF00083.24 KPA38115.1 - 2.7e-85 286.9 24.1 3.1e-85 286.8 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38115.1 - 2.1e-36 125.6 47.9 7.1e-26 91.0 25.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA38115.1 - 2.1e-05 23.1 0.7 2.1e-05 23.1 0.7 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_43 PF04616.14 KPA38116.1 - 1.4e-33 116.5 4.5 2.1e-33 115.9 4.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KPA38116.1 - 2.6e-23 82.8 0.4 3.9e-23 82.2 0.4 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain BLIP PF07467.11 KPA38116.1 - 0.086 13.4 0.1 1.5 9.5 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase inhibitor (BLIP) ADH_zinc_N PF00107.26 KPA38117.1 - 1.5e-12 47.6 0.0 2.7e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA38117.1 - 8.6e-10 38.5 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPA38117.1 - 0.00021 22.4 0.0 0.00076 20.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPA38117.1 - 0.00099 19.0 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase RTBV_P12 PF06361.11 KPA38117.1 - 0.0089 16.4 0.2 0.053 13.9 0.1 2.2 2 0 0 2 2 2 1 Rice tungro bacilliform virus P12 protein Epimerase PF01370.21 KPA38117.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KPA38117.1 - 0.11 12.1 0.1 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA YceG_bac PF14266.6 KPA38117.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' NmrA PF05368.13 KPA38118.1 - 1e-34 120.2 0.0 1.3e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA38118.1 - 1.3e-15 57.8 0.0 1.6e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA38118.1 - 4.8e-05 22.9 0.0 6.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPA38118.1 - 0.0051 16.7 0.1 0.0085 16.0 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KPA38118.1 - 0.033 13.2 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KPA38118.1 - 0.038 14.1 0.0 0.095 12.8 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Lipase_GDSL_2 PF13472.6 KPA38119.1 - 3.6e-06 27.5 0.1 5.3e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA38119.1 - 0.00017 21.6 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Tyrosinase PF00264.20 KPA38121.1 - 3.8e-17 63.3 12.1 1.6e-11 44.9 2.5 2.4 1 1 1 2 2 2 2 Common central domain of tyrosinase COesterase PF00135.28 KPA38125.1 - 1.3e-97 327.8 0.0 1.6e-97 327.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA38125.1 - 2.6e-09 37.3 0.4 2.4e-08 34.1 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA38125.1 - 0.0034 16.9 0.2 0.0061 16.1 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family ECH_1 PF00378.20 KPA38126.1 - 8.4e-44 149.8 0.0 3.9e-32 111.5 0.0 2.3 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA38126.1 - 2.7e-19 69.9 0.3 5.2e-13 49.2 0.2 3.5 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 KPA38127.1 - 1.4e-72 244.6 0.0 2.5e-72 243.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA38127.1 - 0.003 18.5 0.1 0.0074 17.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KPA38128.1 - 8.5e-19 67.6 0.3 1.5e-18 66.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA38128.1 - 3.7e-09 36.5 9.7 8.5e-09 35.4 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FGGY_C PF02782.16 KPA38129.1 - 8.7e-73 244.3 1.1 1.5e-72 243.5 1.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KPA38129.1 - 3.3e-66 223.3 0.0 4.3e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 KPA38130.1 - 3.1e-51 174.3 7.6 3.9e-51 173.9 7.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein DAO PF01266.24 KPA38131.1 - 8.7e-53 180.1 0.0 1.9e-52 179.0 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 KPA38131.1 - 9.6e-41 138.6 0.0 2.2e-40 137.4 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KPA38131.1 - 3.2e-09 36.4 2.1 0.001 18.3 0.7 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KPA38131.1 - 6.8e-06 25.7 0.3 0.00031 20.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA38131.1 - 0.0013 18.0 0.7 0.0039 16.5 0.7 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA38131.1 - 0.021 15.0 0.4 0.2 11.9 0.2 2.7 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPA38131.1 - 0.036 12.8 0.1 0.064 12.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KPA38131.1 - 0.038 13.2 0.1 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA38131.1 - 0.06 12.4 0.1 0.41 9.7 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KPA38131.1 - 0.07 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4148 PF13663.6 KPA38131.1 - 0.096 12.9 0.6 0.33 11.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Thi4 PF01946.17 KPA38131.1 - 0.14 11.4 0.4 1.5 8.0 0.0 2.4 2 1 0 3 3 3 0 Thi4 family Pyr_redox PF00070.27 KPA38131.1 - 0.16 12.5 1.2 0.94 10.1 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HNH_2 PF13391.6 KPA38133.1 - 5.7e-06 26.4 0.1 8.5e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 HNH endonuclease fn3_2 PF16893.5 KPA38133.1 - 0.047 13.8 0.2 0.076 13.2 0.2 1.3 1 0 0 1 1 1 0 Fibronectin type III domain Ank_2 PF12796.7 KPA38134.1 - 1.4e-105 346.1 0.4 4.9e-15 55.9 0.0 10.7 3 2 7 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA38134.1 - 9.7e-86 281.1 2.1 5.2e-08 33.3 0.0 14.2 8 6 6 14 14 14 12 Ankyrin repeats (many copies) Ank PF00023.30 KPA38134.1 - 1.3e-70 231.0 0.5 0.00031 21.1 0.2 19.8 20 0 0 20 20 20 14 Ankyrin repeat Ank_3 PF13606.6 KPA38134.1 - 2.1e-67 215.1 0.0 0.00092 19.5 0.0 19.8 19 0 0 19 19 19 13 Ankyrin repeat Ank_5 PF13857.6 KPA38134.1 - 1.7e-59 197.1 16.0 3.3e-07 30.5 0.0 14.3 4 3 9 15 15 15 14 Ankyrin repeats (many copies) HET PF06985.11 KPA38134.1 - 2.2e-35 122.2 0.0 6.7e-35 120.6 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PNP_UDP_1 PF01048.20 KPA38134.1 - 2.3e-11 43.4 0.7 4.3e-10 39.3 0.7 2.4 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KPA38134.1 - 1.9e-07 31.2 0.0 6.3e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPA38134.1 - 3.8e-05 24.2 0.0 0.00019 21.9 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA38134.1 - 7.6e-05 23.0 0.0 0.00022 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain W2 PF02020.18 KPA38134.1 - 0.028 14.5 0.7 0.4 10.8 0.2 2.9 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon GATase_7 PF13537.6 KPA38134.1 - 0.073 13.0 0.0 15 5.5 0.0 4.7 6 0 0 6 6 6 0 Glutamine amidotransferase domain ubiquitin PF00240.23 KPA38135.1 - 8.6e-09 35.0 0.0 1.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KPA38135.1 - 0.083 12.7 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ribonuc_L-PSP PF01042.21 KPA38136.1 - 3.2e-18 65.9 0.0 3.8e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1107 PF06526.12 KPA38136.1 - 0.0076 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1107) PAP_assoc PF03828.19 KPA38137.1 - 2.3e-10 40.5 0.9 9.6e-10 38.5 0.1 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KPA38137.1 - 7.5e-08 32.6 0.0 1.7e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain LRRNT_2 PF08263.12 KPA38137.1 - 0.03 14.6 2.1 0.04 14.2 0.6 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Fibrinogen_aC PF12160.8 KPA38139.1 - 0.063 13.1 1.3 0.091 12.6 0.0 1.8 2 0 0 2 2 2 0 Fibrinogen alpha C domain zf-C2H2_jaz PF12171.8 KPA38140.1 - 3.3e-14 52.7 20.2 0.00012 22.3 0.2 5.7 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KPA38140.1 - 3.6e-14 52.2 22.4 0.0039 17.9 0.2 6.8 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KPA38140.1 - 2.8e-11 43.7 25.2 0.014 15.7 1.2 6.8 2 2 5 7 7 7 4 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KPA38140.1 - 2.6e-10 40.3 22.9 0.00059 20.1 1.6 5.5 6 0 0 6 6 4 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KPA38140.1 - 5e-08 33.0 21.8 0.067 13.7 0.8 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KPA38140.1 - 1.3e-05 25.4 33.6 0.15 12.5 0.2 7.0 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf_ZIC PF18366.1 KPA38140.1 - 0.00056 20.0 5.3 0.54 10.4 0.1 4.4 4 1 0 4 4 4 1 Zic proteins zinc finger domain C1_4 PF07975.12 KPA38140.1 - 0.019 15.2 21.4 0.39 11.0 0.2 4.9 2 2 3 5 5 5 0 TFIIH C1-like domain AKAP95 PF04988.12 KPA38140.1 - 0.021 15.1 7.0 3.3 7.9 0.1 4.2 2 1 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) Spt46 PF17734.1 KPA38140.1 - 0.057 13.2 5.2 2.8 7.7 0.2 2.9 3 1 0 3 3 3 0 Spermatogenesis-associated protein 46 FAD_SOX PF18371.1 KPA38140.1 - 0.097 13.0 0.0 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Rpr2 PF04032.16 KPA38140.1 - 0.11 12.8 7.6 3.5 8.0 1.1 3.6 3 1 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_6 PF13912.6 KPA38140.1 - 0.26 11.3 27.2 0.79 9.8 1.0 6.0 6 1 1 7 7 6 0 C2H2-type zinc finger Yippee-Mis18 PF03226.14 KPA38140.1 - 0.3 11.3 8.5 0.41 10.9 2.1 3.4 4 0 0 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_9 PF16293.5 KPA38140.1 - 0.41 10.5 12.6 2.5 8.0 0.1 5.7 4 3 3 7 7 7 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 KPA38140.1 - 0.97 9.6 27.2 1.1 9.4 0.4 5.8 5 2 1 6 6 5 0 Zinc ribbon domain zf-MYST PF17772.1 KPA38140.1 - 1.3 8.6 7.7 2.1 8.0 0.2 3.4 4 0 0 4 4 4 0 MYST family zinc finger domain Rad50_zn_hook PF04423.14 KPA38140.1 - 1.8 8.5 0.0 1.8 8.5 0.0 3.1 4 0 0 4 4 4 0 Rad50 zinc hook motif DUF2256 PF10013.9 KPA38140.1 - 2.6 8.2 0.0 2.6 8.2 0.0 5.3 7 0 0 7 7 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KPA38140.1 - 3.5 7.7 19.8 6.4 6.8 0.6 5.7 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Methyltransf_34 PF11312.8 KPA38141.1 - 0.072 12.3 0.2 0.08 12.2 0.2 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase DASH_Duo1 PF08651.10 KPA38141.1 - 0.14 11.9 0.5 0.23 11.3 0.1 1.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF3638 PF12340.8 KPA38142.1 - 2.9e-95 317.9 1.2 6.6e-95 316.7 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KPA38142.1 - 6.5e-18 63.8 0.5 1.3e-17 62.9 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF3638 PF12340.8 KPA38143.1 - 1.4e-72 243.7 0.1 7.2e-72 241.4 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KPA38143.1 - 3.1e-13 48.9 0.1 9.6e-13 47.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Cupin_1 PF00190.22 KPA38144.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KPA38144.1 - 1.2e-05 24.9 1.8 0.00081 19.1 1.8 2.3 1 1 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KPA38144.1 - 0.082 12.6 2.6 0.25 11.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF861) NAD_binding_8 PF13450.6 KPA38145.1 - 1.2e-11 44.7 0.2 1e-10 41.7 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KPA38145.1 - 6.5e-11 41.4 1.0 3.5e-09 35.6 0.3 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPA38145.1 - 2e-07 30.5 0.0 2.7e-06 26.8 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPA38145.1 - 4.1e-06 26.2 0.0 0.001 18.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA38145.1 - 3.1e-05 24.0 0.1 0.045 13.7 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KPA38145.1 - 3.3e-05 23.6 0.1 0.18 11.4 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA38145.1 - 0.0018 17.6 0.1 0.044 13.0 0.0 2.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA38145.1 - 0.0022 17.3 0.0 0.076 12.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Fungal_trans PF04082.18 KPA38146.1 - 2e-12 46.7 1.6 7.3e-12 44.9 0.4 2.4 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA38146.1 - 0.0011 19.1 3.5 0.0033 17.5 3.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPV_P10 PF05531.12 KPA38146.1 - 0.49 10.9 2.4 5 7.7 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ABC2_membrane PF01061.24 KPA38147.1 - 2.1e-78 262.6 55.4 1.6e-41 142.0 22.1 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KPA38147.1 - 5.7e-37 127.3 0.0 1.4e-17 64.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KPA38147.1 - 6.8e-33 112.4 15.3 1.4e-32 111.4 0.0 4.1 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KPA38147.1 - 4.7e-15 56.0 0.2 1.7e-14 54.1 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KPA38147.1 - 1.7e-09 37.2 37.1 2.2e-06 27.1 8.8 2.7 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.6 KPA38147.1 - 2.5e-06 27.7 0.1 0.026 14.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KPA38147.1 - 3.7e-06 27.5 0.0 0.0029 18.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KPA38147.1 - 4.6e-06 26.3 0.0 0.0002 21.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KPA38147.1 - 1.1e-05 25.4 0.7 0.0013 18.7 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KPA38147.1 - 2.1e-05 25.0 0.2 0.02 15.3 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KPA38147.1 - 0.00023 20.8 0.6 0.045 13.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KPA38147.1 - 0.00045 20.1 0.3 1.1 9.0 0.0 3.2 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPA38147.1 - 0.0014 18.1 0.0 0.78 9.1 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KPA38147.1 - 0.0041 17.4 0.4 2.1 8.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 KPA38147.1 - 0.0055 17.1 0.5 0.55 10.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KPA38147.1 - 0.0064 16.4 0.7 1.6 8.6 0.0 3.0 3 0 0 3 3 2 1 NACHT domain dNK PF01712.19 KPA38147.1 - 0.032 14.1 0.0 6.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_30 PF13604.6 KPA38147.1 - 0.041 13.6 0.1 1.9 8.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KPA38147.1 - 0.048 13.2 1.1 1 8.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KPA38147.1 - 0.06 13.6 0.1 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KPA38147.1 - 0.08 13.4 0.1 22 5.5 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KPA38147.1 - 0.12 12.3 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Amidase PF01425.21 KPA38148.1 - 3e-40 138.5 0.6 5.4e-40 137.7 0.2 1.5 2 0 0 2 2 2 1 Amidase rhaM PF05336.13 KPA38148.1 - 0.13 12.4 0.1 12 6.0 0.0 2.5 2 0 0 2 2 2 0 L-rhamnose mutarotase APH PF01636.23 KPA38149.1 - 1.1e-08 35.3 0.1 2e-07 31.2 0.1 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KPA38149.1 - 0.072 12.4 0.0 0.38 10.0 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase Homeobox_KN PF05920.11 KPA38150.1 - 1.8e-15 56.5 1.7 5.8e-15 54.9 1.7 2.0 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KPA38150.1 - 1e-09 38.1 1.1 3.5e-09 36.4 1.1 2.0 1 0 0 1 1 1 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 KPA38150.1 - 1.9e-06 27.8 0.0 0.011 15.8 0.0 2.8 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 KPA38150.1 - 0.00028 21.5 2.1 0.00028 21.5 2.1 4.8 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA38150.1 - 0.0017 18.7 2.4 0.0017 18.7 2.4 4.2 4 0 0 4 4 3 1 Zinc finger, C2H2 type Homez PF11569.8 KPA38150.1 - 0.0054 16.2 3.1 0.0093 15.4 0.4 2.6 2 1 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez zf-H2C2_2 PF13465.6 KPA38150.1 - 0.081 13.4 4.0 2 9.0 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Neur_chan_memb PF02932.16 KPA38150.1 - 0.14 12.2 0.5 0.42 10.6 0.5 2.0 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NUDE_C PF04880.13 KPA38150.1 - 0.46 10.9 4.1 1.3 9.5 4.1 1.7 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Elf1 PF05129.13 KPA38150.1 - 1 9.5 5.0 11 6.2 2.0 2.9 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2_2 PF12756.7 KPA38150.1 - 2.2 8.7 5.3 13 6.2 0.1 3.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KPA38150.1 - 3.9 7.9 7.8 0.32 11.3 1.9 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CGGC PF08821.11 KPA38151.1 - 0.17 12.1 4.8 0.25 11.6 4.8 1.4 1 1 0 1 1 1 0 CGGC domain DUF2797 PF10977.8 KPA38151.1 - 1.3 8.9 6.8 9.6 6.0 6.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2797) Vps39_2 PF10367.9 KPA38151.1 - 1.6 9.2 4.8 0.35 11.3 0.9 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Aminotran_1_2 PF00155.21 KPA38153.1 - 6.9e-28 97.9 0.0 8.2e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KPA38153.1 - 4.8e-05 22.1 0.0 6.9e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 KPA38154.1 - 4.1e-37 127.8 0.0 1.9e-20 72.9 0.0 3.0 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 KPA38154.1 - 8.1e-18 65.0 0.0 1.6e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Wtap PF17098.5 KPA38155.1 - 0.0018 18.2 0.9 0.0064 16.4 0.7 1.8 1 1 1 2 2 2 1 WTAP/Mum2p family Pox_E2-like PF04497.12 KPA38155.1 - 0.018 13.5 0.0 0.021 13.3 0.0 1.0 1 0 0 1 1 1 0 Poxviridae protein Homeobox_KN PF05920.11 KPA38156.1 - 4e-15 55.4 1.2 5.6e-14 51.8 1.0 2.7 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KPA38156.1 - 4.5e-06 26.4 1.4 1.2e-05 25.1 0.1 2.4 3 0 0 3 3 3 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 KPA38156.1 - 4.8e-05 23.3 0.0 0.0076 16.3 0.0 4.1 5 0 0 5 5 5 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 KPA38156.1 - 0.034 15.0 2.5 0.034 15.0 2.5 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA38156.1 - 0.046 14.2 21.1 0.052 14.0 2.5 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type Elf1 PF05129.13 KPA38156.1 - 0.76 9.9 5.8 0.41 10.7 1.5 2.6 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like TPR_10 PF13374.6 KPA38157.1 - 1e-32 111.0 5.1 1e-11 44.3 0.1 4.1 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KPA38157.1 - 5e-29 100.4 4.8 1.6e-21 76.3 1.5 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KPA38157.1 - 1.5e-16 59.4 13.6 1.2e-06 28.1 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPA38157.1 - 2.5e-12 45.9 10.8 0.00029 20.7 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KPA38157.1 - 2.9e-11 43.3 0.1 6.5e-11 42.2 0.0 1.4 1 1 1 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 KPA38157.1 - 4.4e-11 42.1 7.8 0.00018 21.5 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPA38157.1 - 1.6e-10 40.2 7.2 6.9e-05 22.6 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KPA38157.1 - 1.1e-08 35.1 1.0 0.0095 16.7 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KPA38157.1 - 9.2e-07 28.9 0.0 0.061 14.0 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPA38157.1 - 1.2e-06 29.0 7.4 0.046 14.4 0.4 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPA38157.1 - 6e-06 26.3 6.0 0.046 14.1 0.1 4.7 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KPA38157.1 - 9.1e-06 25.3 7.6 0.096 12.4 0.3 3.6 2 1 2 4 4 4 3 TPR repeat TPR_19 PF14559.6 KPA38157.1 - 2.7e-05 24.6 5.3 0.016 15.7 0.2 2.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_21 PF09976.9 KPA38157.1 - 0.00033 20.4 2.5 0.22 11.2 0.2 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain PPR PF01535.20 KPA38157.1 - 0.0022 18.1 0.0 2.2 8.7 0.0 2.8 3 0 0 3 3 2 1 PPR repeat TPR_6 PF13174.6 KPA38157.1 - 0.0035 17.9 13.6 0.16 12.7 0.5 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF2225 PF09986.9 KPA38157.1 - 0.0073 16.0 1.8 2.1 8.0 0.7 2.8 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) DUF4810 PF16068.5 KPA38157.1 - 0.022 15.3 2.2 4.5 7.9 0.1 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4810) SNAP PF14938.6 KPA38157.1 - 0.024 14.0 0.5 0.093 12.1 0.3 2.0 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP Wzy_C_2 PF11846.8 KPA38157.1 - 0.043 13.7 0.2 19 5.1 0.0 2.8 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal RPN7 PF10602.9 KPA38157.1 - 0.094 12.4 0.4 13 5.4 0.1 2.2 1 1 1 2 2 2 0 26S proteasome subunit RPN7 Cyclin_N PF00134.23 KPA38158.1 - 4.6e-12 45.8 1.9 6.1e-12 45.4 0.9 1.7 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KPA38158.1 - 0.0014 19.0 0.1 0.0041 17.5 0.1 1.8 1 0 0 1 1 1 1 Cyclin C-terminal domain Chorion_3 PF05387.11 KPA38158.1 - 0.012 15.3 0.4 0.017 14.8 0.4 1.2 1 0 0 1 1 1 0 Chorion family 3 sCache_2 PF17200.4 KPA38158.1 - 0.084 12.7 0.1 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 Single Cache domain 2 Turandot PF07240.11 KPA38158.1 - 0.1 12.6 0.2 0.31 11.0 0.2 1.8 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot TFIIB PF00382.19 KPA38158.1 - 0.63 10.1 4.0 0.84 9.7 0.2 2.5 2 1 0 2 2 2 0 Transcription factor TFIIB repeat Mito_carr PF00153.27 KPA38159.1 - 1.6e-67 223.4 5.1 5.3e-25 87.2 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KPA38159.1 - 1.1e-20 73.9 6.2 1.1e-10 41.8 1.9 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KPA38159.1 - 1.3e-19 68.2 8.8 7.3e-06 25.2 0.3 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KPA38159.1 - 2.5e-16 58.1 9.6 1.8e-05 24.3 0.2 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KPA38159.1 - 2.1e-15 55.4 9.8 0.00015 21.1 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KPA38159.1 - 6.3e-08 32.3 8.2 0.00042 20.1 0.8 3.5 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KPA38159.1 - 8.9e-06 26.0 0.0 0.012 15.9 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KPA38159.1 - 0.0046 16.9 1.7 0.15 12.0 0.2 2.7 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 KPA38159.1 - 0.092 13.1 1.3 0.77 10.1 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain DUF4097 PF13349.6 KPA38160.1 - 1.8e-08 34.0 1.1 0.0013 18.2 0.0 3.6 3 1 0 3 3 3 2 Putative adhesin CCDC14 PF15254.6 KPA38160.1 - 0.43 9.2 0.7 0.6 8.7 0.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 ATP_bind_3 PF01171.20 KPA38161.1 - 6.4e-40 136.8 0.0 8.5e-28 97.3 0.0 2.4 2 0 0 2 2 2 2 PP-loop family NAD_synthase PF02540.17 KPA38161.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 NAD synthase SOG2 PF10428.9 KPA38162.1 - 0.068 12.4 15.5 0.097 11.9 15.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RAP1 PF07218.11 KPA38162.1 - 0.17 10.1 2.5 0.3 9.3 2.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IKI3 PF04762.12 KPA38164.1 - 0 1013.6 0.0 0 1013.3 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 KPA38164.1 - 0.00036 20.8 0.6 4.3 7.7 0.0 4.8 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KPA38164.1 - 0.072 13.2 5.5 0.24 11.6 0.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPA38164.1 - 0.59 10.0 3.0 0.66 9.9 0.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.20 KPA38164.1 - 1.1 9.2 3.8 9.4 6.1 0.1 2.8 2 1 1 3 3 3 0 Region in Clathrin and VPS TPR_8 PF13181.6 KPA38164.1 - 2.2 8.7 3.9 4.6 7.7 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KPA38164.1 - 3.9 7.8 7.0 15 6.0 0.5 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat Tyrosinase PF00264.20 KPA38166.1 - 6.9e-52 176.9 0.0 1e-51 176.4 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase 3HCDH PF00725.22 KPA38167.1 - 4.2e-21 75.4 0.0 1.3e-20 73.8 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.18 KPA38167.1 - 1.9e-14 53.9 0.1 1.1e-13 51.4 0.1 2.1 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.18 KPA38167.1 - 1.1e-06 28.6 8.8 2.4e-06 27.6 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPA38168.1 - 7.1e-40 137.0 32.1 9.1e-40 136.7 31.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 KPA38169.1 - 9.2e-13 48.5 0.0 1.7e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA38169.1 - 9.3e-12 45.0 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA38169.1 - 1.8e-08 34.7 0.0 2.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA38169.1 - 0.00023 21.2 0.2 0.00064 19.8 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA38169.1 - 0.0024 17.8 0.0 0.0056 16.6 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KPA38169.1 - 0.079 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 KPA38169.1 - 0.089 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain v110 PF01639.17 KPA38170.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Viral family 110 Glyco_hydro_11 PF00457.17 KPA38171.1 - 1.9e-78 262.2 14.6 2.7e-78 261.7 14.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 FR47 PF08445.10 KPA38172.1 - 0.0019 18.2 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein GNAT_C PF18164.1 KPA38172.1 - 0.0072 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 GNAT-like C-terminal domain Acetyltransf_1 PF00583.25 KPA38172.1 - 0.023 14.9 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Sdh_cyt PF01127.22 KPA38173.1 - 8e-17 61.4 2.8 1e-16 61.1 2.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Dioxygenase_C PF00775.21 KPA38174.1 - 3.2e-08 33.2 0.3 3.2e-08 33.2 0.3 1.7 2 1 0 2 2 2 1 Dioxygenase SpaA PF17802.1 KPA38174.1 - 0.1 12.9 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Prealbumin-like fold domain DHHC PF01529.20 KPA38175.1 - 1.7e-36 125.3 7.9 3.5e-36 124.3 7.9 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.17 KPA38175.1 - 0.0092 15.7 0.6 0.0092 15.7 0.6 1.9 2 0 0 2 2 2 1 Yip1 domain DUF4366 PF14283.6 KPA38176.1 - 0.25 11.4 0.0 0.36 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) HAD PF12710.7 KPA38177.1 - 3.7e-23 82.9 0.1 5.5e-23 82.3 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA38177.1 - 1.8e-17 64.3 0.3 2.9e-17 63.7 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KPA38177.1 - 6.5e-09 35.9 1.0 4.4e-08 33.2 0.1 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KPA38177.1 - 3e-05 24.2 0.1 0.00035 20.7 0.1 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KPA38177.1 - 0.0013 18.2 0.1 0.21 11.0 0.0 2.3 2 0 0 2 2 2 2 Putative Phosphatase DUF705 PF05152.12 KPA38177.1 - 0.0063 16.0 0.2 0.0093 15.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) PAPS_reduct PF01507.19 KPA38178.1 - 2.5e-40 138.3 0.0 3.8e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family TYW3 PF02676.14 KPA38179.1 - 1.7e-77 259.5 0.0 2.4e-77 259.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF1690 PF07956.11 KPA38180.1 - 1.2e-43 148.8 7.7 1.5e-43 148.6 7.7 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) GerE PF00196.19 KPA38180.1 - 0.14 11.7 1.3 0.24 11.0 1.3 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Leader_CPA1 PF08252.11 KPA38180.1 - 5.9 6.4 6.9 1.5 8.3 0.8 2.2 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide Ferric_reduct PF01794.19 KPA38181.1 - 4.5e-22 78.5 11.0 8e-22 77.7 7.7 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPA38181.1 - 3.4e-19 69.5 0.0 3.3e-16 59.8 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPA38181.1 - 2.8e-08 33.8 0.0 1.2e-06 28.5 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain Nse4_C PF08743.10 KPA38182.1 - 1.8e-34 117.8 0.0 4.5e-34 116.6 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KPA38182.1 - 1.1e-19 70.3 1.4 2.7e-19 69.0 0.0 2.5 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE API5 PF05918.11 KPA38182.1 - 0.086 11.6 2.1 0.34 9.7 0.0 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) PBP1_TM PF14812.6 KPA38182.1 - 0.63 10.4 17.6 5.8 7.4 6.7 4.3 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 KPA38182.1 - 0.71 9.9 9.5 1.4 9.0 0.0 3.2 3 0 0 3 3 3 0 RXT2-like, N-terminal Nucleo_P87 PF07267.11 KPA38182.1 - 2.2 7.0 8.9 5 5.9 8.9 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Zip PF02535.22 KPA38182.1 - 6.4 5.9 4.9 9.6 5.3 4.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cep57_CLD_2 PF14197.6 KPA38183.1 - 9e-05 22.5 3.2 9e-05 22.5 3.2 2.2 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 KASH_CCD PF14662.6 KPA38183.1 - 0.0033 17.3 2.8 0.0033 17.3 2.8 2.3 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Presenilin PF01080.17 KPA38183.1 - 0.012 14.4 0.0 0.012 14.4 0.0 2.6 2 1 0 2 2 2 0 Presenilin DUF743 PF05332.11 KPA38183.1 - 0.051 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF743) NleF_casp_inhib PF16809.5 KPA38183.1 - 0.41 10.6 5.0 1 9.3 0.4 2.8 3 0 0 3 3 3 0 NleF caspase inhibitor Shugoshin_N PF07558.11 KPA38183.1 - 1.7 8.6 9.0 0.57 10.1 2.1 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 KPA38183.1 - 4.1 7.8 9.8 2 8.8 2.4 3.1 2 1 1 3 3 3 0 TSC-22/dip/bun family ZapB PF06005.12 KPA38183.1 - 6.2 7.3 17.8 0.1 13.0 1.7 3.1 2 1 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 KPA38183.1 - 7.5 7.3 10.7 17 6.1 5.9 3.5 2 1 0 2 2 2 0 Initiation control protein YabA DUF4336 PF14234.6 KPA38184.1 - 1.9e-14 53.6 0.0 1.3e-09 37.7 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) WSC PF01822.19 KPA38185.1 - 8.1e-18 64.4 13.1 1.5e-12 47.5 3.7 2.3 2 0 0 2 2 2 2 WSC domain Opiods_neuropep PF01160.18 KPA38185.1 - 5.8 7.1 8.8 17 5.6 3.1 2.7 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide MFS_1 PF07690.16 KPA38186.1 - 2.8e-14 52.8 12.9 2.8e-14 52.8 12.9 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA38186.1 - 6.9e-06 25.2 10.3 5e-05 22.4 10.3 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_47 PF01532.20 KPA38187.1 - 9.3e-118 394.0 0.0 1.2e-117 393.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_43 PF04616.14 KPA38188.1 - 2.1e-06 27.3 2.4 2.1e-06 27.3 2.4 1.5 1 1 1 2 2 2 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KPA38188.1 - 4e-06 26.6 0.1 5e-05 23.0 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_35 PF01301.19 KPA38189.1 - 1.2e-91 307.6 0.0 1.7e-91 307.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KPA38189.1 - 1e-63 214.4 4.9 1.7e-63 213.7 4.9 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KPA38189.1 - 2.8e-48 163.2 3.2 1.8e-23 83.3 0.0 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KPA38189.1 - 2.7e-18 65.3 0.0 8.3e-18 63.7 0.0 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 DUF4975 PF16346.5 KPA38189.1 - 0.098 12.7 0.2 0.25 11.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) LapA_dom PF06305.11 KPA38190.1 - 0.035 13.9 0.4 0.42 10.5 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TatD_DNase PF01026.21 KPA38191.1 - 5.8e-26 91.4 0.0 8.5e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Abhydrolase_1 PF00561.20 KPA38192.1 - 1.2e-09 38.2 0.1 1.5e-08 34.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA38192.1 - 0.009 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Methyltransf_25 PF13649.6 KPA38194.1 - 4.4e-15 56.2 0.1 1.2e-14 54.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA38194.1 - 4.3e-14 52.9 0.0 7.9e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA38194.1 - 2.8e-07 30.4 0.0 4.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA38194.1 - 1.7e-06 27.6 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KPA38194.1 - 1.8e-06 28.6 0.1 4.4e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA38194.1 - 0.00083 18.9 0.1 0.0014 18.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KPA38194.1 - 0.0021 17.5 0.7 0.003 17.0 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) BBE PF08031.12 KPA38195.1 - 3.2e-20 72.0 1.6 5.6e-20 71.2 1.6 1.4 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 KPA38196.1 - 1e-22 80.6 38.8 1.4e-22 80.1 38.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KPA38198.1 - 4.5e-15 55.4 20.3 4.5e-15 55.4 20.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KPA38199.1 - 2.3e-33 115.7 0.0 3.1e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Med3 PF11593.8 KPA38200.1 - 3.1 6.9 4.4 4 6.5 4.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.16 KPA38201.1 - 9.8e-35 120.1 9.2 9.8e-35 120.1 9.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KPA38202.1 - 1e-27 97.0 1.3 1.3e-27 96.7 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA38202.1 - 2.6e-08 33.8 8.1 4.9e-08 33.0 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.20 KPA38203.1 - 1.4e-37 129.0 13.6 4.6e-30 104.5 0.0 3.7 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KPA38203.1 - 3.7e-20 72.4 4.6 3.7e-20 72.4 4.6 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KPA38203.1 - 8.1e-18 65.5 0.0 1e-13 52.1 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KPA38203.1 - 3.7e-15 55.8 0.0 8.4e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KPA38203.1 - 1.4e-14 53.5 0.0 1.4e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPA38203.1 - 0.00013 21.8 0.2 0.00071 19.4 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Caveolin PF01146.17 KPA38203.1 - 0.13 12.2 1.6 0.65 9.9 0.1 2.4 2 0 0 2 2 2 0 Caveolin PI3K_C2 PF00792.24 KPA38203.1 - 0.13 12.1 0.0 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 PALP PF00291.25 KPA38204.1 - 4.1e-39 134.8 0.1 5.1e-39 134.4 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NBD_C PF17042.5 KPA38204.1 - 0.14 12.7 1.1 0.22 12.0 0.1 1.9 2 0 0 2 2 2 0 Nucleotide-binding C-terminal domain Ank_2 PF12796.7 KPA38205.1 - 1.2e-19 70.7 0.0 5.8e-10 39.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA38205.1 - 5.2e-19 68.4 0.1 1.5e-10 41.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KPA38205.1 - 4.2e-16 58.6 0.6 0.015 15.7 0.1 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KPA38205.1 - 1.5e-13 49.6 0.0 0.33 11.7 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KPA38205.1 - 2e-10 40.7 0.1 0.00061 20.0 0.1 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) bZIP_1 PF00170.21 KPA38205.1 - 0.21 11.7 10.0 0.047 13.8 5.4 2.0 2 0 0 2 2 2 0 bZIP transcription factor DEC-1_N PF04625.13 KPA38205.1 - 0.23 10.4 5.3 0.35 9.8 5.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region bZIP_2 PF07716.15 KPA38205.1 - 0.98 9.6 8.2 0.075 13.1 3.0 1.8 2 0 0 2 2 2 0 Basic region leucine zipper P5CR_dimer PF14748.6 KPA38206.1 - 1.8e-23 82.8 2.6 3.1e-23 82.0 2.6 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation Aminotran_4 PF01063.19 KPA38206.1 - 2.8e-19 69.9 0.0 4.6e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV Fas_alpha_ACP PF18325.1 KPA38207.1 - 6e-55 186.0 0.0 9.6e-54 182.1 0.0 2.3 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KPA38207.1 - 2e-37 128.8 0.0 4e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 KPA38207.1 - 1.8e-21 76.9 1.4 2.6e-21 76.3 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KPA38207.1 - 3.7e-12 46.3 0.0 8.1e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain GDP_Man_Dehyd PF16363.5 KPA38207.1 - 0.044 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Cyt-b5 PF00173.28 KPA38208.1 - 4.3e-12 46.0 0.1 1.6e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF4755 PF15947.5 KPA38208.1 - 0.027 14.4 0.0 4.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4755) NAD_binding_1 PF00175.21 KPA38208.1 - 0.092 13.4 0.0 0.39 11.4 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Trehalose_PPase PF02358.16 KPA38208.1 - 0.098 11.8 0.0 13 4.9 0.0 2.4 2 0 0 2 2 2 0 Trehalose-phosphatase Methyltransf_2 PF00891.18 KPA38209.1 - 7.4e-20 71.1 0.0 9.7e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KPA38209.1 - 2e-07 30.9 0.2 6.1e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain DUF4230 PF14014.6 KPA38209.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) p450 PF00067.22 KPA38210.1 - 6.1e-52 176.9 0.0 7.9e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KPA38211.1 - 2.2e-56 191.6 0.0 3.4e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KPA38211.1 - 8.1e-18 64.5 1.4 1.1e-17 64.0 0.2 1.9 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.12 KPA38211.1 - 6.1e-10 39.0 0.1 1.5e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KPA38211.1 - 0.00014 21.3 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Acetyltransf_1 PF00583.25 KPA38212.1 - 2.4e-09 37.4 0.0 3.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA38212.1 - 3e-09 36.9 0.0 4.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA38212.1 - 8.3e-09 35.8 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA38212.1 - 0.0017 18.4 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KPA38212.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Ank_4 PF13637.6 KPA38213.1 - 1e-20 73.8 0.2 4.1e-07 30.4 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA38213.1 - 4.5e-20 72.0 0.6 1.8e-07 31.7 0.0 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA38213.1 - 2.5e-11 43.6 0.1 0.00042 20.6 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KPA38213.1 - 1.6e-10 41.0 0.4 0.049 14.1 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KPA38213.1 - 8.5e-10 38.0 0.0 0.09 13.4 0.0 5.5 6 1 0 6 6 6 2 Ankyrin repeat Tyrosinase PF00264.20 KPA38214.1 - 4.8e-20 72.8 0.1 6.2e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3602 PF12223.8 KPA38214.1 - 0.039 14.5 0.1 0.29 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) TnsD PF15978.5 KPA38214.1 - 0.17 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D Abhydrolase_6 PF12697.7 KPA38215.1 - 7.9e-11 43.0 0.0 1e-10 42.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA38215.1 - 6.7e-07 28.8 0.0 0.0011 18.3 0.0 3.0 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA38215.1 - 1.4e-05 24.9 0.0 0.0056 16.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 KPA38215.1 - 0.0056 15.5 0.0 0.0075 15.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Thioesterase PF00975.20 KPA38215.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_8 PF06259.12 KPA38215.1 - 0.05 13.2 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase adh_short_C2 PF13561.6 KPA38217.1 - 1.6e-50 171.8 0.9 1.9e-50 171.6 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA38217.1 - 4.8e-42 143.6 1.2 5.6e-42 143.4 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA38217.1 - 8.8e-07 29.0 0.2 1.2e-06 28.6 0.2 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 KPA38217.1 - 0.0015 18.4 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus Epimerase PF01370.21 KPA38217.1 - 0.031 13.7 0.1 0.16 11.4 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TRPM_tetra PF16519.5 KPA38217.1 - 0.043 13.9 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM 3HCDH_N PF02737.18 KPA38217.1 - 0.077 12.9 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 KPA38218.1 - 0.14 10.9 1.0 0.27 10.0 0.0 1.9 3 0 0 3 3 3 0 Fungal specific transcription factor domain DUF5329 PF17263.2 KPA38218.1 - 0.16 12.2 0.6 0.31 11.2 0.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5329) DUF4887 PF16228.5 KPA38218.1 - 0.97 9.6 9.2 1.4 9.0 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) MFS_1 PF07690.16 KPA38219.1 - 6.9e-36 123.9 22.9 2.2e-35 122.3 23.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 KPA38219.1 - 2.8 7.8 4.7 3 7.7 0.8 3.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 KPA38222.1 - 3.6e-35 121.5 25.9 3.6e-35 121.5 25.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA38222.1 - 3.4e-09 36.1 25.3 6.5e-09 35.2 25.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2070 PF09843.9 KPA38222.1 - 0.0031 15.9 4.5 0.0031 15.9 4.5 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2070) Na_H_Exchanger PF00999.21 KPA38223.1 - 3.4e-05 22.8 5.1 4.8e-05 22.3 5.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family F-box PF00646.33 KPA38223.1 - 4.5e-05 23.2 0.4 0.00016 21.4 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KPA38223.1 - 0.0036 17.2 0.2 0.0036 17.2 0.2 2.2 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 KPA38223.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 F-box DUF3382 PF11862.8 KPA38223.1 - 0.037 14.3 0.7 0.083 13.2 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Bromodomain PF00439.25 KPA38224.1 - 1.5e-31 108.3 0.0 7.6e-18 64.4 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KPA38224.1 - 1.2e-11 44.6 0.6 2.8e-11 43.4 0.6 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation adh_short PF00106.25 KPA38226.1 - 6.6e-19 68.1 0.0 2e-12 47.0 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA38226.1 - 8.5e-10 38.6 0.0 0.00011 21.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KPA38226.1 - 1.1e-05 25.5 0.1 2.4e-05 24.3 0.0 1.7 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KPA38226.1 - 0.0013 18.2 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPA38226.1 - 0.071 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 KR domain FAD_binding_4 PF01565.23 KPA38227.1 - 2.2e-18 66.4 1.9 3.9e-18 65.5 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPA38227.1 - 2.3e-06 27.6 0.0 5.5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like HARP PF07443.13 KPA38227.1 - 0.1 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 HepA-related protein (HARP) DAO PF01266.24 KPA38228.1 - 2.1e-44 152.6 0.1 2.3e-44 152.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA38228.1 - 3.1e-05 23.4 1.9 0.0008 18.7 2.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA38228.1 - 4.3e-05 22.8 2.2 0.038 13.1 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KPA38228.1 - 0.00013 22.0 0.2 0.28 11.2 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPA38228.1 - 0.00014 22.0 0.1 0.0003 21.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KPA38228.1 - 0.0028 18.1 0.0 0.0071 16.8 0.0 1.9 2 1 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KPA38228.1 - 0.016 14.3 0.3 1.6 7.7 0.0 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 KPA38228.1 - 0.024 14.3 0.7 0.056 13.1 0.2 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KPA38228.1 - 0.024 14.9 0.5 0.044 14.0 0.1 1.6 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 KPA38228.1 - 0.024 13.7 3.5 0.067 12.3 3.5 1.8 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KPA38228.1 - 0.047 12.9 0.2 0.47 9.7 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.15 KPA38228.1 - 0.049 12.2 0.1 0.22 10.0 0.0 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.14 KPA38228.1 - 0.073 11.8 1.2 1.6 7.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 KPA38228.1 - 0.08 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KPA38228.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1188 PF06690.11 KPA38228.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Trp_halogenase PF04820.14 KPA38228.1 - 0.29 9.9 2.0 1.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Peptidase_S8 PF00082.22 KPA38231.1 - 2.1e-34 119.2 5.1 2.5e-34 118.9 5.1 1.1 1 0 0 1 1 1 1 Subtilase family Utp14 PF04615.13 KPA38232.1 - 3.6 6.1 11.1 4.6 5.7 11.1 1.0 1 0 0 1 1 1 0 Utp14 protein RNA_ligase PF09414.10 KPA38233.1 - 0.082 13.2 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA ligase Glyco_hydro_18 PF00704.28 KPA38234.1 - 1.2e-55 189.4 0.2 2.6e-55 188.4 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KPA38234.1 - 1.3e-09 38.4 13.1 1.3e-09 38.4 13.1 3.7 3 0 0 3 3 3 2 Chitin recognition protein DNase_NucA_NucB PF14040.6 KPA38234.1 - 6e-06 26.6 1.4 0.00034 21.0 0.0 3.2 3 0 0 3 3 3 1 Deoxyribonuclease NucA/NucB Chitin_bind_1 PF00187.19 KPA38235.1 - 6e-05 23.4 42.9 0.043 14.3 17.6 2.8 2 0 0 2 2 2 2 Chitin recognition protein tRNA-synt_1c PF00749.21 KPA38236.1 - 4.8e-97 324.6 0.0 6.3e-97 324.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KPA38236.1 - 2.8e-38 131.5 0.0 4.1e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KPA38236.1 - 0.0066 15.8 0.9 0.017 14.5 0.9 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Glyco_hydro_76 PF03663.14 KPA38238.1 - 1.3e-146 488.9 7.9 1.5e-146 488.6 7.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 GFA PF04828.14 KPA38241.1 - 4.9e-07 30.0 5.9 0.0049 17.2 0.1 2.7 1 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Vac7 PF12751.7 KPA38241.1 - 0.22 10.9 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 zf-NADH-PPase PF09297.11 KPA38241.1 - 4.2 7.1 9.9 0.19 11.4 2.0 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Ank_4 PF13637.6 KPA38242.1 - 7.7e-27 93.3 3.0 3.7e-06 27.4 0.1 7.7 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA38242.1 - 1.6e-23 83.1 0.3 2.6e-07 31.1 0.0 4.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA38242.1 - 2.1e-16 58.3 5.0 0.028 14.9 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KPA38242.1 - 4.7e-15 55.5 8.8 0.00021 21.5 0.0 7.2 4 3 3 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 KPA38242.1 - 6.9e-15 54.7 2.1 0.00079 19.8 0.0 7.2 7 0 0 7 7 7 2 Ankyrin repeat Imm49 PF15575.6 KPA38242.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 49 Hydrolase_4 PF12146.8 KPA38246.1 - 1.5e-06 27.7 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA38246.1 - 2.3e-05 24.2 0.4 0.0016 18.2 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA38246.1 - 5.4e-05 23.9 0.1 7.8e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KPA38246.1 - 0.048 13.5 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA38246.1 - 0.085 12.3 0.1 4.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 KPA38246.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Ribosom_S30AE_C PF16321.5 KPA38246.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus Zn_clus PF00172.18 KPA38247.1 - 8.5e-05 22.6 8.1 0.0002 21.4 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_2 PF07883.11 KPA38248.1 - 3.4e-09 36.3 0.1 0.00024 20.8 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Ppnp PF06865.11 KPA38248.1 - 0.00048 20.5 0.0 0.00089 19.6 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase AraC_binding PF02311.19 KPA38248.1 - 0.0011 18.8 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_6 PF12852.7 KPA38248.1 - 0.0055 16.4 0.0 0.75 9.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.12 KPA38248.1 - 0.016 14.9 0.1 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KPA38248.1 - 0.089 12.7 0.0 3 7.7 0.0 2.1 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase Egh16-like PF11327.8 KPA38249.1 - 2e-60 204.4 1.2 2.4e-60 204.1 1.2 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Fungal_trans_2 PF11951.8 KPA38250.1 - 1e-11 44.3 0.1 1.9e-11 43.5 0.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA38250.1 - 1.7e-07 31.2 8.7 1.7e-07 31.2 8.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2235 PF09994.9 KPA38251.1 - 4.1e-24 85.4 0.0 7.6e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) AIG1 PF04548.16 KPA38251.1 - 1.1e-05 24.9 0.0 2.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KPA38251.1 - 1.6e-05 25.0 0.0 3.9e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KPA38251.1 - 6.9e-05 22.3 0.6 0.0032 16.8 0.0 2.2 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 KPA38251.1 - 8.4e-05 22.5 0.4 0.0038 17.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 KPA38251.1 - 0.00079 19.3 1.8 0.048 13.4 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KPA38251.1 - 0.0099 16.4 4.7 0.86 10.1 0.6 2.7 2 0 0 2 2 2 2 AAA domain Gtr1_RagA PF04670.12 KPA38251.1 - 0.012 15.0 0.3 0.035 13.5 0.3 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Roc PF08477.13 KPA38251.1 - 0.017 15.3 0.4 0.2 11.9 0.4 2.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA38251.1 - 0.019 14.4 0.5 1.3 8.5 0.2 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.6 KPA38251.1 - 0.032 14.5 0.0 0.2 11.9 0.0 2.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KPA38251.1 - 0.076 13.1 1.1 0.55 10.3 0.2 2.5 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.15 KPA38251.1 - 0.081 12.8 0.1 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 KPA38251.1 - 0.098 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KPA38251.1 - 0.12 13.0 0.0 0.37 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KPA38251.1 - 0.12 12.9 0.5 0.37 11.3 0.5 1.9 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KPA38251.1 - 0.13 11.4 0.8 0.28 10.3 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain TPX2 PF06886.11 KPA38251.1 - 1.9 8.7 5.7 5.2 7.4 5.7 1.7 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) ABC_membrane PF00664.23 KPA38252.1 - 1.9e-81 273.7 28.1 9.7e-46 156.6 7.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA38252.1 - 5.9e-61 205.0 0.0 6.4e-29 101.2 0.0 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPA38252.1 - 9.4e-15 54.6 0.0 5.1e-06 26.1 0.3 3.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KPA38252.1 - 1.2e-07 32.3 1.7 0.03 14.7 0.4 4.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 KPA38252.1 - 1.3e-07 31.5 0.1 0.014 15.1 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KPA38252.1 - 1.4e-07 31.1 1.3 0.00079 19.1 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KPA38252.1 - 2.5e-07 31.1 0.2 0.018 15.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 KPA38252.1 - 5.6e-06 25.4 0.4 0.089 11.6 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KPA38252.1 - 7.4e-06 26.0 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KPA38252.1 - 1.6e-05 24.5 0.2 0.31 10.5 0.0 3.0 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_15 PF13175.6 KPA38252.1 - 8.5e-05 22.4 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KPA38252.1 - 8.9e-05 22.4 0.1 0.47 10.2 0.1 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 KPA38252.1 - 9.9e-05 22.1 2.4 0.32 10.6 0.0 3.3 3 1 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 KPA38252.1 - 0.00018 21.7 3.6 1 9.7 0.2 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KPA38252.1 - 0.00024 21.7 0.6 0.22 12.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KPA38252.1 - 0.00052 20.3 0.0 0.75 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KPA38252.1 - 0.0011 19.4 0.6 20 5.6 0.0 4.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KPA38252.1 - 0.0016 18.4 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 KPA38252.1 - 0.0027 18.3 0.0 2.8 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KPA38252.1 - 0.004 17.2 0.1 7.1 6.6 0.0 3.2 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KPA38252.1 - 0.0064 16.1 0.9 3.8 7.1 0.0 3.5 4 0 0 4 4 4 1 AAA domain SRP54 PF00448.22 KPA38252.1 - 0.011 15.4 0.0 6.3 6.4 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KPA38252.1 - 0.011 15.9 0.1 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KPA38252.1 - 0.021 15.1 0.0 1 9.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain Synapsin_N PF10581.9 KPA38252.1 - 0.037 14.0 0.0 9.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Synapsin N-terminal ATP_bind_1 PF03029.17 KPA38252.1 - 0.038 13.8 0.0 0.73 9.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KPA38252.1 - 0.076 12.7 0.2 6.6 6.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KPA38252.1 - 0.085 12.3 0.1 17 4.7 0.0 3.2 4 0 0 4 4 4 0 Bacterial TniB protein AAA_14 PF13173.6 KPA38252.1 - 0.092 12.8 0.0 42 4.2 0.0 3.7 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 KPA38252.1 - 0.13 11.9 1.3 3.9 7.2 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF87 PF01935.17 KPA38252.1 - 0.14 12.3 0.2 0.76 9.8 0.0 2.3 3 0 0 3 3 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KPA38252.1 - 0.15 12.4 0.1 34 4.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.20 KPA38252.1 - 0.21 10.7 0.0 15 4.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_17 PF13207.6 KPA38252.1 - 0.39 11.2 3.4 31 5.0 0.1 3.6 4 0 0 4 4 3 0 AAA domain Zn_clus PF00172.18 KPA38253.1 - 1.2e-08 34.9 14.4 2.1e-08 34.1 14.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GH3 PF03321.13 KPA38253.1 - 0.25 10.1 0.0 0.41 9.4 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Sulfatase PF00884.23 KPA38254.1 - 1.6e-18 67.2 1.6 1.6e-18 67.2 0.6 1.5 2 0 0 2 2 2 1 Sulfatase DUF229 PF02995.17 KPA38254.1 - 0.00036 19.3 0.0 0.00055 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Glyco_transf_5 PF08323.11 KPA38254.1 - 0.00086 19.1 0.5 0.0019 17.9 0.5 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Phosphodiest PF01663.22 KPA38254.1 - 0.003 17.2 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase AAA PF00004.29 KPA38255.1 - 1.9e-17 63.9 0.0 3.9e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA38255.1 - 0.0033 17.7 0.1 0.024 14.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA38255.1 - 0.004 17.5 0.4 0.004 17.5 0.4 2.7 3 1 0 3 3 3 1 AAA ATPase domain Zot PF05707.12 KPA38255.1 - 0.0072 16.0 0.0 0.12 12.0 0.0 2.5 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_33 PF13671.6 KPA38255.1 - 0.091 12.9 0.0 0.091 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KPA38255.1 - 0.12 11.3 0.7 0.33 9.9 0.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TauD PF02668.16 KPA38256.1 - 3.6e-63 213.9 0.7 5e-63 213.4 0.7 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_1 PF00561.20 KPA38258.1 - 1.4e-13 51.0 0.1 4.1e-12 46.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA38258.1 - 1.1e-10 41.2 0.1 4e-10 39.4 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA38258.1 - 8.9e-10 39.5 0.0 1.1e-09 39.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KPA38258.1 - 3.1e-07 30.2 0.9 0.00012 21.7 0.0 2.4 3 0 0 3 3 3 2 Dienelactone hydrolase family BAAT_C PF08840.11 KPA38258.1 - 1.8e-05 24.7 0.1 0.00031 20.7 0.0 2.3 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KPA38258.1 - 0.00014 21.6 0.0 0.00084 19.1 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KPA38258.1 - 0.00057 19.4 0.3 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family PhoPQ_related PF10142.9 KPA38258.1 - 0.00086 18.1 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Thioesterase PF00975.20 KPA38258.1 - 0.0013 18.9 0.0 0.0019 18.3 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.18 KPA38258.1 - 0.0014 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 KPA38258.1 - 0.084 12.7 0.0 7 6.4 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ima1_N PF09779.9 KPA38259.1 - 2e-36 125.8 3.0 4.1e-36 124.8 3.0 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain Casein_kappa PF00997.18 KPA38259.1 - 0.0024 18.0 0.2 0.0052 16.9 0.2 1.5 1 0 0 1 1 1 1 Kappa casein DZR PF12773.7 KPA38259.1 - 0.022 14.8 2.1 5.7 7.0 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF2407_C PF13373.6 KPA38260.1 - 7.6e-35 120.1 0.0 1.1e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KPA38260.1 - 7.1e-29 100.4 0.0 1.1e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KPA38260.1 - 1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF4589 PF15252.6 KPA38260.1 - 0.031 14.3 0.5 0.043 13.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Rad60-SLD_2 PF13881.6 KPA38260.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like rRNA_proc-arch PF13234.6 KPA38261.1 - 4.9e-90 302.1 0.5 1.5e-88 297.3 0.0 2.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KPA38261.1 - 6.3e-52 175.6 2.3 6.3e-52 175.6 2.3 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KPA38261.1 - 2.9e-19 69.5 0.1 1.5e-18 67.2 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA38261.1 - 4.4e-07 30.2 0.0 1.6e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA38261.1 - 5.9e-06 26.4 0.0 2.9e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KPA38261.1 - 0.029 14.6 0.0 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KPA38261.1 - 0.042 12.9 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Prp19 PF08606.11 KPA38261.1 - 0.26 11.3 1.2 3.7 7.6 0.2 2.6 2 0 0 2 2 2 0 Prp19/Pso4-like COX7C PF02935.16 KPA38262.1 - 5.3e-25 87.5 3.1 7.5e-25 87.0 3.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc PPR_2 PF13041.6 KPA38263.1 - 1.1e-13 51.2 3.2 0.00017 21.7 0.1 5.3 4 1 2 6 6 6 4 PPR repeat family PPR PF01535.20 KPA38263.1 - 1.4e-09 37.5 7.4 0.00029 20.9 0.1 5.0 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 KPA38263.1 - 1.1e-05 25.4 1.6 0.037 14.1 0.1 4.3 2 2 2 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KPA38263.1 - 0.00041 19.8 0.8 0.0026 17.2 0.2 2.2 1 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KPA38263.1 - 0.026 14.2 2.3 19 5.0 0.0 4.1 4 0 0 4 4 4 0 PPR repeat MRP-S25 PF13741.6 KPA38264.1 - 4.7e-62 209.6 12.5 5.2e-57 193.1 6.2 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KPA38264.1 - 6.7e-05 23.2 1.1 0.00012 22.4 0.3 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein S23 B_solenoid_dext PF18841.1 KPA38264.1 - 0.18 12.1 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 Beta solenoid repeat from Dextranase Alg14 PF08660.11 KPA38265.1 - 5.8e-33 114.3 0.7 1.4e-21 77.2 0.0 2.2 1 1 1 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like ECF_trnsprt PF12822.7 KPA38265.1 - 0.041 14.0 0.5 0.13 12.4 0.1 1.8 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Ras PF00071.22 KPA38266.1 - 1.2e-09 37.9 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Ras family DAO PF01266.24 KPA38267.1 - 7.2e-35 121.2 1.2 8.5e-35 121.0 1.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA38267.1 - 2.5e-05 23.7 0.3 8.5e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA38267.1 - 4.9e-05 23.4 0.7 0.01 15.8 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPA38267.1 - 0.0025 17.1 0.1 0.022 14.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA38267.1 - 0.0079 16.4 0.1 0.024 14.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KPA38267.1 - 0.042 13.1 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KPA38267.1 - 0.043 13.1 1.8 0.047 12.9 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KPA38267.1 - 0.059 13.9 0.5 0.91 10.1 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KPA38267.1 - 0.061 11.9 1.0 1.2 7.6 0.1 2.5 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.14 KPA38267.1 - 0.081 11.6 0.2 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KPA38267.1 - 0.2 10.7 1.1 1.5 7.8 0.3 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 KPA38267.1 - 0.21 10.7 0.2 1.2 8.3 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Amidase PF01425.21 KPA38268.1 - 5.5e-105 351.9 0.0 1.2e-104 350.9 0.0 1.5 1 1 0 1 1 1 1 Amidase PRELI PF04707.14 KPA38269.1 - 5.1e-41 140.1 0.1 5.9e-41 139.9 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family Peptidase_M24 PF00557.24 KPA38270.1 - 4.6e-44 150.6 0.0 5.9e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3243 PF11588.8 KPA38270.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) YL1 PF05764.13 KPA38270.1 - 0.39 10.8 7.5 0.69 10.0 7.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein AhpC-TSA_2 PF13911.6 KPA38271.1 - 1.1e-15 57.7 0.0 2.5e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KPA38271.1 - 0.0032 17.4 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family AAA_18 PF13238.6 KPA38272.1 - 5.2e-06 27.0 0.0 1.3e-05 25.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KPA38272.1 - 1.4e-05 25.0 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KPA38272.1 - 0.00062 19.9 0.2 0.12 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KPA38272.1 - 0.0012 18.1 0.8 0.0018 17.5 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_17 PF13207.6 KPA38272.1 - 0.0021 18.5 0.0 0.33 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KPA38272.1 - 0.0032 17.1 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase Zeta_toxin PF06414.12 KPA38272.1 - 0.019 14.3 0.2 0.044 13.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Torsin PF06309.11 KPA38272.1 - 0.037 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Torsin RuvB_N PF05496.12 KPA38272.1 - 0.049 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 KPA38272.1 - 0.051 12.6 0.1 0.35 9.9 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein MeaB PF03308.16 KPA38272.1 - 0.076 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 KPA38272.1 - 0.087 12.0 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.17 KPA38272.1 - 0.23 11.2 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF1918 PF08940.11 KPA38274.1 - 0.08 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) NmrA PF05368.13 KPA38275.1 - 2.5e-44 151.6 0.0 3.1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA38275.1 - 6.1e-15 55.6 0.2 8.2e-15 55.2 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KPA38275.1 - 0.00044 19.3 0.0 0.00061 18.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPA38275.1 - 0.00085 18.8 0.0 0.0017 17.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family E3_UbLigase_EDD PF11547.8 KPA38275.1 - 0.002 17.8 0.0 1.9 8.3 0.1 2.4 2 0 0 2 2 2 2 E3 ubiquitin ligase EDD DXP_reductoisom PF02670.16 KPA38275.1 - 0.017 15.8 0.1 0.048 14.4 0.1 1.8 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 KPA38275.1 - 0.021 15.1 0.1 0.043 14.1 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KPA38275.1 - 0.032 14.5 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain SKG6 PF08693.10 KPA38276.1 - 2.3e-07 30.1 1.4 4.1e-07 29.3 1.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KPA38276.1 - 0.0011 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 KPA38276.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 TMEM154 protein family MLANA PF14991.6 KPA38276.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A Rax2 PF12768.7 KPA38276.1 - 0.028 13.9 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4328 PF14219.6 KPA38276.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) MHYT PF03707.16 KPA38276.1 - 0.1 12.8 0.3 0.26 11.5 0.3 1.7 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Chitin_synth_1 PF01644.17 KPA38277.1 - 3.1e-74 248.4 0.2 4.7e-74 247.8 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KPA38277.1 - 1.5e-26 92.2 0.0 3.2e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KPA38277.1 - 3e-24 85.5 2.2 1.5e-18 66.8 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KPA38277.1 - 1.3e-06 28.5 4.3 1.3e-06 28.5 4.3 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 GMC_oxred_N PF00732.19 KPA38279.1 - 1.5e-42 146.0 0.0 2.4e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA38279.1 - 5.9e-35 120.9 0.0 1.1e-34 120.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Aa_trans PF01490.18 KPA38280.1 - 3.8e-34 118.1 32.3 4.7e-34 117.8 32.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Acyl_transf_3 PF01757.22 KPA38280.1 - 0.0072 15.4 12.4 0.0072 15.4 12.4 2.7 1 1 2 3 3 3 1 Acyltransferase family DUF1118 PF06549.12 KPA38280.1 - 0.067 13.5 3.8 22 5.4 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1118) NADH-u_ox-rdase PF10785.9 KPA38280.1 - 7.5 7.3 9.9 2 9.2 0.2 3.8 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit MFS_1 PF07690.16 KPA38281.1 - 2e-13 50.0 55.4 1.3e-08 34.2 26.1 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA38281.1 - 0.065 11.6 17.9 0.11 10.9 17.9 1.4 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF4538 PF15061.6 KPA38281.1 - 2.6 7.9 4.1 6.2 6.6 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) SET PF00856.28 KPA38283.1 - 4.6e-16 59.7 0.2 9.8e-16 58.6 0.2 1.6 1 1 0 1 1 1 1 SET domain eIF_4EBP PF05456.11 KPA38283.1 - 0.0097 15.8 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) FidL_like PF15941.5 KPA38283.1 - 0.056 13.9 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 FidL-like putative membrane protein SQS_PSY PF00494.19 KPA38283.1 - 0.056 12.9 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Squalene/phytoene synthase Fungal_trans PF04082.18 KPA38285.1 - 1.5e-12 47.1 3.2 4.9e-12 45.4 3.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Lipase_GDSL_2 PF13472.6 KPA38286.1 - 9.3e-10 39.2 0.3 1.3e-09 38.7 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA38286.1 - 0.0013 18.7 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HMMR_C PF15908.5 KPA38286.1 - 0.13 12.6 0.1 0.22 11.8 0.1 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Tri3 PF07428.11 KPA38287.1 - 1.4e-05 24.2 0.3 2.5e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 15-O-acetyltransferase Tri3 p450 PF00067.22 KPA38288.1 - 5.4e-41 140.8 0.0 6.5e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Exo_endo_phos PF03372.23 KPA38289.1 - 9.5e-08 31.8 0.2 2.3e-07 30.6 0.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BNR_4 PF15892.5 KPA38290.1 - 3.9e-71 239.6 4.3 4.8e-71 239.3 4.3 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member BNR_2 PF13088.6 KPA38290.1 - 0.00026 20.4 0.0 0.00054 19.3 0.0 1.5 1 0 0 1 1 1 1 BNR repeat-like domain DUF1080 PF06439.11 KPA38290.1 - 0.0052 16.9 0.1 0.013 15.7 0.1 1.5 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1080) Ytp1 PF10355.9 KPA38291.1 - 5.6e-118 393.2 9.7 8.9e-118 392.5 9.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KPA38291.1 - 2e-30 104.7 6.6 2e-30 104.7 6.6 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) SNF2_N PF00176.23 KPA38292.1 - 1.9e-59 201.2 0.0 3.3e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KPA38292.1 - 9.3e-53 179.1 0.3 2.8e-52 177.5 0.5 1.7 2 0 0 2 2 2 1 Rad54 N terminal Rsa3 PF14615.6 KPA38292.1 - 1.7e-17 62.7 0.1 3.4e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Helicase_C PF00271.31 KPA38292.1 - 7.6e-16 58.4 0.0 2.4e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA38292.1 - 2.1e-10 40.9 0.0 4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KPA38292.1 - 0.0019 17.4 0.0 0.011 15.0 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Mito_carr PF00153.27 KPA38294.1 - 1.8e-43 146.3 4.5 1e-16 60.6 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Rab5ip PF07019.12 KPA38294.1 - 7.7 7.2 9.1 4.9 7.8 1.3 3.4 3 1 0 3 3 3 0 Rab5-interacting protein (Rab5ip) Bromodomain PF00439.25 KPA38295.1 - 3.8e-42 142.2 0.3 6.9e-22 77.3 0.2 2.7 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KPA38295.1 - 5.3e-18 65.1 0.4 1.4e-17 63.7 0.4 1.8 1 0 0 1 1 1 1 BAH domain CDC45 PF02724.14 KPA38295.1 - 1.9e-05 23.2 10.5 1.9e-05 23.2 10.5 1.7 2 0 0 2 2 2 1 CDC45-like protein RTP PF02334.16 KPA38295.1 - 3.1 8.4 5.6 0.52 11.0 0.8 2.1 2 0 0 2 2 2 0 Replication terminator protein DUF913 PF06025.12 KPA38295.1 - 3.4 6.6 4.0 1.5 7.7 0.4 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RNA_pol_3_Rpc31 PF11705.8 KPA38295.1 - 4.3 7.5 44.9 0.036 14.3 10.6 4.6 4 0 0 4 4 4 0 DNA-directed RNA polymerase III subunit Rpc31 OTU PF02338.19 KPA38296.1 - 1.5e-09 38.4 0.0 2.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease EI24 PF07264.11 KPA38297.1 - 6.2e-18 65.7 6.2 2.6e-15 57.1 6.2 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.7 KPA38298.1 - 8e-45 152.2 0.0 2.2e-44 150.8 0.0 1.8 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 RTA1 PF04479.13 KPA38299.1 - 5.8e-32 111.0 4.5 7.1e-32 110.7 4.5 1.1 1 0 0 1 1 1 1 RTA1 like protein Ninjurin PF04923.12 KPA38299.1 - 2.9 7.9 10.0 17 5.4 10.0 2.1 1 1 0 1 1 1 0 Ninjurin Fungal_trans PF04082.18 KPA38301.1 - 0.0011 18.1 0.3 0.002 17.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 KPA38302.1 - 1.2e-68 231.5 0.0 1.5e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ZnuA PF01297.17 KPA38302.1 - 0.04 13.3 0.2 5.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic ADH_zinc_N PF00107.26 KPA38303.1 - 6.1e-22 78.0 0.5 9.1e-22 77.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA38303.1 - 4.4e-21 74.8 0.7 4.4e-21 74.8 0.7 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPA38303.1 - 3.6e-05 24.8 0.3 6.8e-05 23.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MinC_N PF05209.13 KPA38303.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain Varsurf_PPLC PF03490.13 KPA38305.1 - 2.6e-05 24.1 0.1 5.4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C Delta_lysin PF05372.11 KPA38305.1 - 0.022 14.0 0.3 0.046 13.0 0.3 1.5 1 0 0 1 1 1 0 Delta lysin family DUF4064 PF13273.6 KPA38306.1 - 0.0082 16.4 0.3 0.0082 16.4 0.3 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4064) HTH_Tnp_Tc5 PF03221.16 KPA38307.1 - 0.00016 21.6 0.0 0.00057 19.9 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Fungal_trans_2 PF11951.8 KPA38308.1 - 3.5e-46 157.7 4.4 4.7e-46 157.3 4.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain VSP PF03302.13 KPA38309.1 - 0.0005 19.0 2.2 0.0005 19.0 2.2 1.6 2 0 0 2 2 2 1 Giardia variant-specific surface protein Aa_trans PF01490.18 KPA38310.1 - 3.2e-44 151.3 33.3 3.7e-44 151.1 33.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Asparaginase PF00710.20 KPA38312.1 - 5e-20 71.9 0.0 7.1e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KPA38312.1 - 0.00057 20.1 0.0 0.0023 18.1 0.0 2.1 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Glyco_transf_8 PF01501.20 KPA38313.1 - 0.00069 19.2 1.1 0.047 13.2 1.1 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Ornatin PF02088.15 KPA38313.1 - 0.16 11.7 0.6 0.34 10.7 0.6 1.5 1 0 0 1 1 1 0 Ornatin zf-C2HE PF16278.5 KPA38314.1 - 0.001 19.4 3.5 0.3 11.6 0.1 2.8 2 0 0 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KPA38314.1 - 0.0012 18.6 0.3 0.0012 18.6 0.3 2.7 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KPA38314.1 - 0.0013 19.4 25.4 0.21 12.5 0.2 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA38314.1 - 0.0026 18.1 27.5 0.025 15.0 0.3 4.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 KPA38314.1 - 0.0095 15.8 8.9 2.6 8.0 0.1 4.3 4 0 0 4 4 4 2 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 KPA38314.1 - 0.046 13.7 0.8 0.046 13.7 0.8 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Helo_like_N PF17111.5 KPA38316.1 - 3.3e-07 29.9 0.0 3.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins CCD48 PF15799.5 KPA38316.1 - 0.0084 14.5 0.0 0.0099 14.2 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 SesA PF17107.5 KPA38316.1 - 0.099 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 KPA38317.1 - 1.2e-05 25.3 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPA38317.1 - 4e-05 24.1 0.0 6.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA38317.1 - 0.00072 19.8 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KPA38317.1 - 0.033 13.4 0.0 0.074 12.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Ank_2 PF12796.7 KPA38318.1 - 2.1e-05 25.0 0.1 0.00077 20.0 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KPA38318.1 - 0.00074 19.9 0.2 11 6.7 0.0 4.4 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KPA38318.1 - 0.0016 18.8 0.5 2.4 9.0 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 KPA38318.1 - 0.04 14.5 0.0 0.5 11.0 0.0 2.7 3 1 1 4 4 4 0 Ankyrin repeats (many copies) APH PF01636.23 KPA38319.1 - 9.3e-13 48.7 0.1 2e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KPA38319.1 - 0.00024 20.1 0.0 0.00043 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KPA38319.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KPA38319.1 - 0.0025 17.4 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KPA38319.1 - 0.075 12.4 0.0 4.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain MFS_1 PF07690.16 KPA38320.1 - 1.1e-28 100.2 28.8 1.6e-28 99.7 28.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA38320.1 - 4.7e-08 32.3 14.8 3.7e-07 29.4 14.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Methyltransf_23 PF13489.6 KPA38321.1 - 2.3e-16 60.1 0.0 5.6e-16 58.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA38321.1 - 1.2e-11 45.2 0.0 3.3e-09 37.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA38321.1 - 3.1e-09 37.4 0.0 3.6e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA38321.1 - 3.1e-09 36.8 0.0 0.0033 17.2 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KPA38321.1 - 1.1e-07 32.5 0.0 1.5e-06 28.9 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KPA38321.1 - 0.032 13.7 0.0 6.4 6.2 0.0 2.7 2 1 1 3 3 3 0 Putative methyltransferase FtsJ PF01728.19 KPA38321.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KPA38322.1 - 2.4e-06 27.0 0.0 0.00067 19.0 0.0 2.8 2 1 1 3 3 3 2 O-methyltransferase domain Methyltransf_23 PF13489.6 KPA38322.1 - 0.046 13.6 0.0 0.34 10.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain DUF1929 PF09118.11 KPA38323.1 - 5e-26 90.8 0.2 1.3e-25 89.5 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 KPA38323.1 - 2.7e-20 72.8 1.3 6.6e-20 71.5 0.7 2.0 2 0 0 2 2 2 1 F5/8 type C domain Kelch_6 PF13964.6 KPA38323.1 - 8e-13 48.2 6.6 0.007 16.6 0.0 5.5 5 1 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KPA38323.1 - 7.8e-09 35.0 3.5 1.3e-05 24.7 0.2 4.7 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KPA38323.1 - 6.4e-08 32.5 2.3 0.00014 21.8 0.1 5.3 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.15 KPA38323.1 - 8.1e-07 28.8 1.3 0.32 11.0 0.1 5.0 5 0 0 5 5 5 2 Kelch motif Glyoxal_oxid_N PF07250.11 KPA38323.1 - 2.5e-05 23.6 0.2 0.024 13.8 0.1 2.5 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_5 PF13854.6 KPA38323.1 - 0.0012 18.8 2.3 0.26 11.3 0.0 4.1 5 0 0 5 5 5 1 Kelch motif XRCC1_N PF01834.16 KPA38323.1 - 0.22 11.5 0.0 0.37 10.8 0.0 1.2 1 0 0 1 1 1 0 XRCC1 N terminal domain Fungal_trans PF04082.18 KPA38324.1 - 0.022 13.8 1.7 0.034 13.2 1.7 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain InaF-motif PF15018.6 KPA38324.1 - 0.15 11.9 4.7 0.32 10.9 0.0 2.7 2 0 0 2 2 2 0 TRP-interacting helix NmrA PF05368.13 KPA38325.1 - 6.9e-20 71.6 0.0 9.6e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA38325.1 - 1.1e-15 58.1 0.0 1.9e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPA38325.1 - 9.4e-06 25.9 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPA38325.1 - 1.1e-05 25.0 0.1 2.5e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPA38325.1 - 0.00082 19.3 0.0 0.0018 18.2 0.0 1.6 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.24 KPA38325.1 - 0.034 14.6 0.5 0.16 12.4 0.5 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KPA38325.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KPA38325.1 - 0.13 11.7 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase AHH PF14412.6 KPA38325.1 - 0.14 12.3 0.1 13 5.9 0.1 2.2 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Polysacc_synt_2 PF02719.15 KPA38325.1 - 0.16 11.0 0.1 0.32 10.1 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Aldedh PF00171.22 KPA38326.1 - 5.8e-126 420.7 0.0 7.3e-126 420.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPA38326.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) LuxC PF05893.14 KPA38326.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Amino_oxidase PF01593.24 KPA38327.1 - 1.2e-52 179.7 0.1 2.6e-52 178.7 0.1 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA38327.1 - 1.2e-11 44.7 0.1 2.4e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA38327.1 - 2.5e-10 40.5 0.8 1.7e-06 27.9 0.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA38327.1 - 1.7e-07 30.8 0.0 1.2e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA38327.1 - 5.3e-06 25.7 0.0 0.00027 20.1 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KPA38327.1 - 7.5e-06 25.4 0.1 1.3e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KPA38327.1 - 1.4e-05 25.1 1.1 0.0083 16.1 0.1 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KPA38327.1 - 2.2e-05 23.8 0.3 3.7e-05 23.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KPA38327.1 - 5.1e-05 22.8 0.1 0.00012 21.5 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA38327.1 - 0.00018 20.4 0.7 0.00069 18.4 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KPA38327.1 - 0.0008 18.7 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KPA38327.1 - 0.00086 19.8 0.1 0.0023 18.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA38327.1 - 0.0052 15.9 1.7 0.049 12.7 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPA38327.1 - 0.024 13.9 0.5 6.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cupin_3 PF05899.12 KPA38328.1 - 5.1e-05 22.9 0.0 9.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KPA38328.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Pirin PF02678.16 KPA38328.1 - 0.017 15.1 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Pirin Peptidase_S58 PF03576.14 KPA38330.1 - 3.2e-116 388.0 1.8 3.7e-116 387.8 1.8 1.0 1 0 0 1 1 1 1 Peptidase family S58 CBM_4_9 PF02018.17 KPA38331.1 - 6.6e-07 29.7 0.2 6.6e-07 29.7 0.2 2.1 2 1 0 2 2 2 1 Carbohydrate binding domain DUF642 PF04862.12 KPA38331.1 - 0.015 15.1 0.2 0.077 12.8 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF642) Peptidase_M20 PF01546.28 KPA38332.1 - 5.8e-28 98.0 0.0 9.8e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 BTB PF00651.31 KPA38332.1 - 4.9e-19 68.6 0.3 1.3e-18 67.2 0.3 1.7 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.18 KPA38332.1 - 3.7e-17 62.2 3.8 6.6e-17 61.4 3.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TF_Zn_Ribbon PF08271.12 KPA38332.1 - 0.0013 18.2 1.8 0.0037 16.7 1.8 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Peptidase_M28 PF04389.17 KPA38332.1 - 0.0047 16.6 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Prok-RING_1 PF14446.6 KPA38332.1 - 0.0064 16.4 0.4 0.018 14.9 0.4 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 M20_dimer PF07687.14 KPA38332.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Peptidase dimerisation domain HypA PF01155.19 KPA38332.1 - 0.25 11.4 2.2 0.62 10.1 2.2 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS91 PF14319.6 KPA38332.1 - 0.37 10.8 4.3 0.9 9.6 4.3 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain DZR PF12773.7 KPA38332.1 - 0.42 10.7 2.6 1.5 8.9 2.6 2.0 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KPA38332.1 - 0.46 10.5 2.5 1.1 9.2 1.9 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain ADK_lid PF05191.14 KPA38332.1 - 1.2 9.2 5.9 3.4 7.7 0.5 2.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-H2C2_2 PF13465.6 KPA38332.1 - 2.7 8.6 5.8 12 6.5 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger double domain TFIIS_C PF01096.18 KPA38332.1 - 4.5 7.2 6.8 16 5.4 0.3 3.3 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-C2H2_4 PF13894.6 KPA38332.1 - 4.9 8.3 6.8 13 6.9 0.6 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger MFS_1 PF07690.16 KPA38333.1 - 2e-43 148.7 29.2 2.9e-43 148.2 29.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Mannosidase_ig PF17786.1 KPA38333.1 - 0.05 14.2 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 Mannosidase Ig/CBM-like domain HET PF06985.11 KPA38334.1 - 1.4e-32 113.0 0.5 2.9e-32 112.0 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3433 PF11915.8 KPA38335.1 - 2.2e-14 53.7 3.8 2.2e-14 53.7 3.8 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3433) Cellulase PF00150.18 KPA38336.1 - 1.1e-22 80.8 2.3 1.6e-22 80.3 2.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KPA38336.1 - 1.3e-12 47.5 12.0 3.1e-12 46.2 12.0 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF4038 PF13204.6 KPA38336.1 - 4.4e-06 26.6 2.9 7e-06 25.9 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 KPA38336.1 - 1.1e-05 24.7 0.0 3.2e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KPA38336.1 - 0.00013 21.5 0.2 0.00066 19.1 0.1 2.1 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_10 PF00331.20 KPA38336.1 - 0.0048 16.1 0.0 0.0095 15.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 Toxin_7 PF05980.12 KPA38336.1 - 0.056 13.7 3.1 0.11 12.8 3.1 1.4 1 0 0 1 1 1 0 Toxin 7 Ppx-GppA PF02541.16 KPA38337.1 - 3.9e-32 111.8 0.0 5e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 KPA38337.1 - 0.011 14.4 0.1 0.018 13.7 0.1 1.3 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Latarcin PF10279.9 KPA38337.1 - 0.081 13.3 0.0 0.097 13.1 0.0 1.2 1 0 0 1 1 1 0 Latarcin precursor ABC2_membrane PF01061.24 KPA38338.1 - 3.9e-73 245.3 61.5 2.7e-42 144.6 22.5 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KPA38338.1 - 7.8e-34 117.1 0.0 4.7e-17 62.8 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KPA38338.1 - 1.8e-22 79.0 0.0 1.8e-22 79.0 0.0 4.0 4 0 0 4 4 3 1 CDR ABC transporter ABC_trans_N PF14510.6 KPA38338.1 - 4.8e-10 39.9 0.0 1.2e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KPA38338.1 - 3.3e-06 27.6 0.2 0.0019 18.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KPA38338.1 - 3.2e-05 23.9 0.0 0.0018 18.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KPA38338.1 - 0.00014 21.7 0.4 0.087 12.6 0.1 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KPA38338.1 - 0.00024 21.2 0.0 0.072 13.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KPA38338.1 - 0.00032 20.3 0.1 0.029 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPA38338.1 - 0.00059 19.5 0.7 0.097 12.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 KPA38338.1 - 0.00082 19.3 0.2 0.049 13.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain T2SSE PF00437.20 KPA38338.1 - 0.002 17.2 0.1 0.53 9.3 0.0 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_18 PF13238.6 KPA38338.1 - 0.0027 18.3 0.0 0.018 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPA38338.1 - 0.0031 17.8 0.3 0.053 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KPA38338.1 - 0.0077 16.0 0.3 1.4 8.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain Ploopntkinase3 PF18751.1 KPA38338.1 - 0.017 15.1 0.1 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 KPA38338.1 - 0.018 14.7 0.1 0.54 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KPA38338.1 - 0.023 14.9 0.1 0.061 13.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KPA38338.1 - 0.04 14.1 0.6 0.31 11.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KPA38338.1 - 0.042 13.6 0.1 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 KPA38338.1 - 0.07 13.1 0.4 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KPA38338.1 - 0.1 12.2 1.0 0.34 10.5 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KPA38338.1 - 0.14 11.8 0.3 0.27 10.8 0.3 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KPA38338.1 - 0.16 11.2 0.1 0.75 9.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 KPA38338.1 - 0.59 9.9 1.8 4.8 6.9 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ABC2_membrane_3 PF12698.7 KPA38338.1 - 1.2 8.1 68.2 1.9 7.5 31.4 3.2 2 1 0 2 2 2 0 ABC-2 family transporter protein Ion_trans_2 PF07885.16 KPA38339.1 - 2.7e-35 120.1 18.8 1e-17 63.9 6.1 2.7 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KPA38339.1 - 3.8e-06 26.3 14.3 0.0024 17.2 3.1 2.6 3 0 0 3 3 3 2 Ion transport protein Sugar_tr PF00083.24 KPA38340.1 - 3.2e-60 204.3 25.7 3.9e-60 204.0 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38340.1 - 2.5e-12 46.4 36.1 2.8e-12 46.2 26.0 3.0 1 1 1 3 3 3 3 Major Facilitator Superfamily Bac_rhamnosid6H PF17389.2 KPA38341.1 - 1.1e-116 389.8 0.0 1.5e-116 389.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KPA38341.1 - 2.9e-57 193.2 0.0 6.2e-57 192.2 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KPA38341.1 - 4e-27 94.2 0.0 8.7e-27 93.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KPA38341.1 - 5.4e-20 71.0 0.2 1.3e-19 69.8 0.2 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Peptidase_A4 PF01828.17 KPA38342.1 - 7.9e-71 237.8 15.6 9.4e-71 237.6 15.6 1.1 1 0 0 1 1 1 1 Peptidase A4 family Arteri_nucleo PF01481.16 KPA38342.1 - 0.0059 16.9 0.1 0.0097 16.2 0.1 1.3 1 0 0 1 1 1 1 Arterivirus nucleocapsid protein Aha1_N PF09229.11 KPA38342.1 - 0.11 12.7 0.1 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal Sugar_tr PF00083.24 KPA38343.1 - 1.9e-106 356.7 25.2 5.8e-106 355.1 25.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38343.1 - 7.7e-23 81.0 38.5 1e-15 57.6 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.21 KPA38344.1 - 1.6e-136 455.7 33.1 2e-136 455.4 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA38344.1 - 4.8e-37 127.8 36.2 6.2e-37 127.4 36.2 1.1 1 0 0 1 1 1 1 Amino acid permease YnfE PF17452.2 KPA38346.1 - 0.018 15.3 0.3 0.084 13.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized YnfE-like Glyco_hydro_88 PF07470.13 KPA38346.1 - 0.056 12.5 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Sec34 PF04136.15 KPA38346.1 - 0.067 13.1 0.1 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Sec34-like family Bacillus_HBL PF05791.11 KPA38346.1 - 0.076 12.8 0.1 0.076 12.8 0.1 1.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF5082 PF16888.5 KPA38346.1 - 0.16 12.3 1.9 0.6 10.4 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 KPA38346.1 - 0.27 11.7 4.0 7.5 7.1 0.2 3.7 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein TPP_enzyme_N PF02776.18 KPA38347.1 - 2.5e-29 102.1 0.0 4.1e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPA38347.1 - 5.4e-20 71.5 0.0 2.7e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KPA38347.1 - 1.1e-09 38.2 0.3 1.7e-08 34.4 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NCD2 PF04905.13 KPA38347.1 - 0.047 13.7 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) CAMP_factor PF07373.11 KPA38347.1 - 0.19 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 CAMP factor (Cfa) MFS_1 PF07690.16 KPA38348.1 - 2.5e-19 69.4 46.5 3.1e-18 65.9 38.7 3.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA38348.1 - 9.8e-06 24.7 13.6 9.8e-06 24.7 13.6 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 KPA38349.1 - 6.2e-33 114.2 33.6 6.3e-33 114.2 32.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA38349.1 - 1.1e-12 47.2 9.3 1.6e-12 46.7 9.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPA38349.1 - 3.9e-11 42.5 3.4 3.9e-11 42.5 3.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter GTP_EFTU_D2 PF03144.25 KPA38349.1 - 0.17 12.3 0.4 0.4 11.1 0.4 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 MFS_1 PF07690.16 KPA38350.1 - 5.9e-22 78.1 17.0 5.9e-22 78.1 17.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KPA38350.1 - 0.0064 14.8 1.4 0.14 10.4 0.1 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Pro_dh PF01619.18 KPA38351.1 - 8.2e-61 206.1 0.0 9.8e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase DUF4434 PF14488.6 KPA38351.1 - 0.14 12.1 0.0 1.3 9.0 0.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Peptidase_M20 PF01546.28 KPA38352.1 - 1.5e-06 28.1 0.2 3.2e-06 27.0 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPA38352.1 - 6e-06 26.1 0.5 0.0011 18.9 0.1 2.9 2 1 0 2 2 2 2 Peptidase dimerisation domain Aminotran_3 PF00202.21 KPA38353.1 - 3.6e-108 361.8 0.0 4.3e-108 361.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KPA38353.1 - 0.0061 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Hydrolase PF00702.26 KPA38354.1 - 1.8e-05 25.2 0.0 3.3e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KPA38354.1 - 5.6e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Glyoxalase PF00903.25 KPA38356.1 - 2.2e-05 24.6 0.0 0.00037 20.7 0.0 2.1 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Hydrolase_6 PF13344.6 KPA38357.1 - 2.7e-22 78.8 0.0 5.7e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA38357.1 - 2.3e-19 69.2 0.0 5.4e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KPA38357.1 - 0.13 12.5 0.1 4.4 7.5 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.21 KPA38358.1 - 1.6e-52 178.5 0.0 5.7e-52 176.7 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Homeobox_KN PF05920.11 KPA38359.1 - 6.7e-18 64.3 2.0 1.9e-17 62.9 1.0 2.4 3 0 0 3 3 3 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KPA38359.1 - 7.2e-07 29.1 0.3 0.12 12.5 0.1 4.0 3 0 0 3 3 3 2 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KPA38359.1 - 2.4e-06 27.3 1.9 2.8e-06 27.1 0.2 2.0 2 0 0 2 2 2 1 Homeodomain zf-C2H2_4 PF13894.6 KPA38359.1 - 0.00065 20.3 20.8 0.0035 18.1 1.9 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA38359.1 - 0.0023 18.3 21.9 0.004 17.5 2.2 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KPA38359.1 - 3.8 7.9 7.5 85 3.6 0.1 3.5 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) DAO PF01266.24 KPA38362.1 - 9.6e-38 130.6 0.0 1.1e-37 130.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 KPA38362.1 - 2.8e-05 23.7 0.2 0.00031 20.2 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KPA38362.1 - 0.00012 21.4 0.5 0.34 10.1 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA38362.1 - 0.00028 21.1 0.0 0.00054 20.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPA38362.1 - 0.00031 20.0 0.2 0.032 13.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain TrkA_N PF02254.18 KPA38362.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain GIDA PF01134.22 KPA38362.1 - 0.0021 17.2 0.1 0.036 13.1 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KPA38362.1 - 0.0026 18.3 0.2 0.36 11.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA38362.1 - 0.0044 17.0 0.4 2.1 8.3 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding ApbA PF02558.16 KPA38362.1 - 0.029 14.0 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 KPA38362.1 - 0.047 12.9 0.1 0.096 11.9 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Sacchrp_dh_NADP PF03435.18 KPA38362.1 - 0.061 13.6 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 KPA38362.1 - 0.09 12.9 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain p450 PF00067.22 KPA38363.1 - 5.3e-44 150.7 0.0 7.7e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KPA38363.1 - 5.6e-20 71.5 7.9 1.1e-19 70.6 7.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPA38363.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like zf-C2H2_6 PF13912.6 KPA38364.1 - 0.055 13.5 0.3 0.1 12.6 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger ACC_epsilon PF13822.6 KPA38365.1 - 0.48 11.2 3.8 0.97 10.2 3.8 1.5 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Glyco_hyd_65N_2 PF14498.6 KPA38366.1 - 3e-61 207.3 0.1 3.9e-61 206.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain NmrA PF05368.13 KPA38367.1 - 1.2e-09 38.1 0.0 2e-09 37.3 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA38367.1 - 3.2e-08 33.7 0.0 4e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding BBE PF08031.12 KPA38368.1 - 0.0011 19.0 0.4 0.0011 19.0 0.4 1.8 2 0 0 2 2 2 1 Berberine and berberine like G6PD_N PF00479.22 KPA38368.1 - 0.083 13.5 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 KPA38368.1 - 0.087 12.6 0.4 0.17 11.6 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain YCII PF03795.14 KPA38370.1 - 9.6e-05 22.7 0.0 0.00011 22.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain ADH_N_2 PF16884.5 KPA38371.1 - 0.064 13.2 0.0 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Aminotran_4 PF01063.19 KPA38372.1 - 3.3e-16 59.8 0.0 4e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV HTH_Tnp_Tc5 PF03221.16 KPA38373.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain zf-met PF12874.7 KPA38373.1 - 0.47 10.9 0.1 0.47 10.9 0.1 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type MFS_1 PF07690.16 KPA38374.1 - 2.7e-39 135.1 56.9 6.1e-28 97.8 22.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4006 PF13179.6 KPA38374.1 - 0.0008 19.3 0.4 0.12 12.3 0.1 2.6 2 0 0 2 2 2 2 Family of unknown function (DUF4006) DUF373 PF04123.13 KPA38374.1 - 1.3 8.4 5.7 2.6 7.4 5.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF373) HRI1 PF16815.5 KPA38376.1 - 1.5e-68 231.0 0.1 1.7e-68 230.8 0.1 1.0 1 0 0 1 1 1 1 Protein HRI1 Gemini_C4 PF01492.17 KPA38376.1 - 0.035 14.0 0.2 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Geminivirus C4 protein PaREP1 PF05942.11 KPA38376.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family PAN_1 PF00024.26 KPA38377.1 - 5.1e-17 61.6 33.1 0.00018 21.4 1.6 5.7 5 0 0 5 5 5 5 PAN domain PAN_4 PF14295.6 KPA38377.1 - 8.4e-11 41.6 25.1 0.043 13.7 0.1 6.0 5 0 0 5 5 5 5 PAN domain PAN_2 PF08276.11 KPA38377.1 - 7.1e-08 32.5 28.5 0.063 13.4 1.2 6.0 5 0 0 5 5 5 5 PAN-like domain PAN_3 PF08277.12 KPA38377.1 - 0.27 11.1 24.5 2.6 7.9 0.3 5.6 5 0 0 5 5 5 0 PAN-like domain Pec_lyase_C PF00544.19 KPA38378.1 - 1.2e-44 152.4 0.9 1.6e-44 152.0 0.9 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KPA38378.1 - 0.0022 17.8 4.9 0.43 10.4 4.9 2.3 1 1 0 1 1 1 1 Right handed beta helix region YWFCY PF14293.6 KPA38378.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 YWFCY protein MFS_1 PF07690.16 KPA38379.1 - 2.6e-33 115.4 24.7 8.7e-32 110.4 27.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA38379.1 - 6.9e-11 41.7 14.8 1.7e-10 40.3 14.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2138 PF09909.9 KPA38379.1 - 0.079 11.3 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) TAP_C PF03943.13 KPA38379.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain PY_rept_46 PF09689.10 KPA38379.1 - 0.21 12.2 1.6 0.23 12.0 0.4 1.7 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) Hydrophobin_2 PF06766.11 KPA38380.1 - 4e-13 49.1 2.2 4.7e-13 48.9 2.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin AAA_12 PF13087.6 KPA38381.1 - 3.2e-25 88.9 0.5 8e-25 87.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KPA38381.1 - 0.00021 21.7 0.1 0.00021 21.7 0.1 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA38381.1 - 0.012 15.8 1.1 0.038 14.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KPA38381.1 - 0.02 14.9 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPA38381.1 - 0.069 13.5 1.3 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain UvrD_C_2 PF13538.6 KPA38381.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Selenoprotein_S PF06936.11 KPA38381.1 - 0.12 12.2 9.7 0.22 11.3 9.7 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) AAA_30 PF13604.6 KPA38381.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain PEPcase PF00311.17 KPA38381.1 - 0.61 8.1 4.8 0.88 7.6 4.8 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase OmpH PF03938.14 KPA38381.1 - 5.7 7.3 15.6 9.8 6.5 15.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 KPA38381.1 - 6.4 6.0 7.3 11 5.2 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WSC PF01822.19 KPA38382.1 - 1.8e-05 24.8 0.2 1.8e-05 24.8 0.2 2.0 2 0 0 2 2 2 1 WSC domain eIF-5_eIF-2B PF01873.17 KPA38382.1 - 0.27 11.1 3.0 0.51 10.2 3.0 1.4 1 0 0 1 1 1 0 Domain found in IF2B/IF5 adh_short PF00106.25 KPA38383.1 - 5.4e-34 117.4 0.0 6.9e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA38383.1 - 1.1e-17 64.4 0.0 1.3e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA38383.1 - 2.7e-05 24.2 0.5 4e-05 23.6 0.5 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA38383.1 - 0.00017 21.2 0.6 0.00067 19.2 0.6 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KPA38383.1 - 0.00035 20.2 0.1 0.00054 19.6 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KPA38383.1 - 0.00088 19.3 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KPA38383.1 - 0.0029 17.9 0.2 0.0047 17.2 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KPA38383.1 - 0.0059 17.2 0.1 0.01 16.4 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 KPA38383.1 - 0.012 15.5 0.1 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_2 PF03446.15 KPA38383.1 - 0.081 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RTT107_BRCT_5 PF16770.5 KPA38383.1 - 0.098 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain HET PF06985.11 KPA38384.1 - 8.3e-07 29.5 0.5 0.0056 17.0 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zinc_ribbon_2 PF13240.6 KPA38385.1 - 3.7e-05 23.3 8.7 5.8e-05 22.7 8.7 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KPA38385.1 - 9e-05 22.4 2.2 0.00015 21.7 2.2 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KPA38385.1 - 0.0028 18.4 1.6 0.0042 17.8 1.6 1.3 1 0 0 1 1 1 1 zinc-ribbon family zf-ribbon_3 PF13248.6 KPA38385.1 - 0.0075 15.6 6.3 0.012 15.0 6.3 1.3 1 0 0 1 1 1 1 zinc-ribbon domain NOB1_Zn_bind PF08772.11 KPA38385.1 - 0.15 12.3 3.9 0.29 11.3 3.9 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Nudix_N_2 PF14803.6 KPA38385.1 - 0.25 11.3 9.0 0.8 9.7 0.5 2.5 2 0 0 2 2 2 0 Nudix N-terminal DUF2321 PF10083.9 KPA38385.1 - 0.52 9.9 4.4 3.8 7.1 4.4 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Rrn6 PF10214.9 KPA38385.1 - 1.5 7.2 5.9 1.9 6.9 5.9 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Arrestin_C PF02752.22 KPA38387.1 - 0.15 12.5 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain DUF1929 PF09118.11 KPA38388.1 - 7.7e-26 90.2 0.2 1.6e-25 89.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KPA38388.1 - 5.7e-15 55.0 2.9 0.00042 20.5 0.0 4.7 3 1 1 4 4 4 3 Kelch motif PAN_1 PF00024.26 KPA38388.1 - 4.8e-14 52.1 9.4 5e-07 29.6 1.1 2.4 2 0 0 2 2 2 2 PAN domain Kelch_4 PF13418.6 KPA38388.1 - 6.8e-12 45.2 11.4 0.0034 17.3 0.4 5.8 4 2 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KPA38388.1 - 4.6e-10 39.1 0.2 0.0039 17.1 0.0 4.9 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KPA38388.1 - 5.8e-10 38.6 1.3 0.0012 18.3 0.0 4.2 3 1 0 3 3 3 2 Kelch motif Glyoxal_oxid_N PF07250.11 KPA38388.1 - 1.2e-05 24.7 0.0 0.059 12.6 0.0 3.3 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus PAN_4 PF14295.6 KPA38388.1 - 4.4e-05 23.3 10.4 0.014 15.3 3.0 2.6 2 0 0 2 2 2 2 PAN domain Transpeptidase PF00905.22 KPA38388.1 - 0.015 14.5 0.2 0.23 10.7 0.0 2.7 3 0 0 3 3 3 0 Penicillin binding protein transpeptidase domain MANEC PF07502.14 KPA38388.1 - 0.024 14.9 11.4 0.077 13.3 2.7 2.4 2 0 0 2 2 2 0 MANEC domain Kelch_3 PF13415.6 KPA38388.1 - 0.052 13.8 0.1 7.9 6.9 0.0 3.1 2 0 0 2 2 2 0 Galactose oxidase, central domain PAN_3 PF08277.12 KPA38388.1 - 0.054 13.3 8.0 1 9.2 1.1 2.4 2 0 0 2 2 2 0 PAN-like domain GPI-anchored PF10342.9 KPA38389.1 - 3.3e-05 24.6 0.2 5.1e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peptidase_M24 PF00557.24 KPA38391.1 - 3.8e-27 95.4 0.0 5.7e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KPA38391.1 - 0.0019 18.9 0.0 0.0091 16.7 0.0 2.0 1 1 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Spc7_C2 PF15577.6 KPA38392.1 - 0.017 15.2 0.8 8.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Spc7_C2 ADH_N PF08240.12 KPA38393.1 - 0.00038 20.3 0.0 0.00081 19.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA38393.1 - 0.014 15.3 0.1 0.054 13.5 0.1 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PLA2_B PF01735.18 KPA38394.1 - 9.4e-18 63.9 0.1 3.1e-13 49.0 0.2 2.8 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Tachykinin PF02202.16 KPA38394.1 - 0.12 12.4 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 Tachykinin family Amidase PF01425.21 KPA38395.1 - 3.8e-65 220.6 0.0 3.6e-64 217.4 0.0 2.0 1 1 0 1 1 1 1 Amidase Spc7 PF08317.11 KPA38396.1 - 3 6.7 5.9 4.6 6.0 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HET PF06985.11 KPA38397.1 - 1.2e-32 113.3 0.3 2.2e-32 112.4 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyoxalase_4 PF13669.6 KPA38397.1 - 8.8e-15 54.9 0.1 3e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acetyltransf_14 PF03421.16 KPA38397.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase FTCD_C PF04961.12 KPA38397.1 - 0.18 11.5 0.1 0.4 10.4 0.1 1.5 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase AhpC-TSA PF00578.21 KPA38398.1 - 5.4e-38 129.7 0.0 7.1e-38 129.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPA38398.1 - 1.9e-15 56.8 0.0 2.5e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KPA38398.1 - 6.5e-12 45.1 0.0 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KPA38398.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 SCO1/SenC Pyridoxal_deC PF00282.19 KPA38399.1 - 3.3e-63 213.6 0.0 4.6e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 KPA38399.1 - 3.3e-08 33.1 0.0 5.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPA38399.1 - 3.8e-08 32.7 0.0 5.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KPA38399.1 - 2e-06 27.3 0.0 2.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 KPA38399.1 - 8.2e-05 21.5 0.0 0.00013 20.8 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS TTL PF03133.15 KPA38400.1 - 3.8e-34 118.2 0.0 2.6e-33 115.4 0.0 1.9 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KPA38400.1 - 0.00014 21.2 0.0 0.00031 20.1 0.0 1.6 2 0 0 2 2 2 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 KPA38400.1 - 0.003 17.1 0.0 0.024 14.2 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Avl9 PF09794.9 KPA38401.1 - 0.069 11.8 0.1 0.097 11.4 0.1 1.1 1 0 0 1 1 1 0 Transport protein Avl9 DAO PF01266.24 KPA38403.1 - 4.1e-39 135.2 0.0 4.7e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA38403.1 - 9.1e-07 29.0 0.0 5.6e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPA38403.1 - 3.3e-05 24.4 0.0 8.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA38403.1 - 0.00029 20.2 0.0 0.00062 19.1 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain DUF4780 PF16012.5 KPA38403.1 - 0.00093 18.7 0.0 0.081 12.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4780) Pyr_redox_2 PF07992.14 KPA38403.1 - 0.0017 17.7 0.0 0.0093 15.2 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KPA38403.1 - 0.0026 17.8 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KPA38403.1 - 0.0026 17.3 0.0 0.0096 15.4 0.0 1.8 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus NAD_binding_9 PF13454.6 KPA38403.1 - 0.012 15.6 0.0 0.11 12.5 0.0 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 KPA38403.1 - 0.019 14.6 0.1 0.048 13.3 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KPA38403.1 - 0.051 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KPA38403.1 - 0.052 12.9 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 ThiF family Trp_halogenase PF04820.14 KPA38403.1 - 0.073 11.9 0.0 3.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 KPA38403.1 - 0.087 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KPA38403.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KPA38403.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 KPA38403.1 - 0.18 11.3 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KPA38403.1 - 0.21 12.1 0.0 0.42 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding mRNA_stabil PF13929.6 KPA38403.1 - 0.23 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 mRNA stabilisation Thiolase_N PF00108.23 KPA38404.1 - 3.3e-18 66.0 0.0 2.3e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPA38404.1 - 4.5e-12 45.7 0.1 2.7e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KPA38404.1 - 6.5e-06 25.9 0.1 0.00016 21.4 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 KPA38404.1 - 0.00011 22.2 0.9 0.0043 17.0 0.0 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 KPA38404.1 - 0.02 13.6 0.2 0.12 11.0 0.1 2.0 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 KPA38404.1 - 0.04 13.5 0.1 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain NAD_binding_10 PF13460.6 KPA38405.1 - 0.00037 20.5 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Fungal_trans PF04082.18 KPA38406.1 - 1.3e-10 40.7 0.0 3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA38406.1 - 2.8e-06 27.4 17.8 6.3e-06 26.2 17.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF_4EBP PF05456.11 KPA38406.1 - 0.09 12.7 1.4 0.19 11.6 1.4 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Tcf25 PF04910.14 KPA38407.1 - 3.3e-66 223.7 0.4 5.4e-66 223.1 0.4 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 LSM14 PF12701.7 KPA38408.1 - 3.7e-32 110.3 0.1 5.6e-32 109.7 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KPA38408.1 - 4e-22 79.0 1.0 4e-22 79.0 1.0 1.7 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KPA38408.1 - 4.9e-06 26.6 0.0 9.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.11 KPA38408.1 - 3.9 6.2 4.2 7.8 5.2 4.2 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) V-SNARE PF05008.15 KPA38409.1 - 7.2e-20 71.1 2.5 7.2e-20 71.1 2.5 1.7 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KPA38409.1 - 3.3e-17 62.5 1.2 3.3e-17 62.5 1.2 2.5 4 0 0 4 4 3 1 Snare region anchored in the vesicle membrane C-terminus FAM219A PF15260.6 KPA38409.1 - 0.0095 16.3 1.1 0.0095 16.3 1.1 1.8 2 0 0 2 2 2 1 Protein family FAM219A UCMA PF17085.5 KPA38409.1 - 0.03 14.3 0.6 0.052 13.6 0.6 1.4 1 0 0 1 1 1 0 Unique cartilage matrix associated protein FAM76 PF16046.5 KPA38409.1 - 0.069 12.5 0.3 0.069 12.5 0.3 1.4 2 0 0 2 2 2 0 FAM76 protein YusW PF14039.6 KPA38409.1 - 0.13 12.8 0.2 0.23 12.0 0.2 1.4 1 0 0 1 1 1 0 YusW-like protein Sec20 PF03908.13 KPA38409.1 - 0.15 12.0 2.1 0.28 11.1 0.1 2.3 2 2 0 2 2 2 0 Sec20 DUF4449 PF14613.6 KPA38409.1 - 0.18 11.9 0.9 0.28 11.3 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Fusion_gly PF00523.18 KPA38409.1 - 0.21 9.8 1.7 0.24 9.6 0.7 1.6 2 0 0 2 2 2 0 Fusion glycoprotein F0 Use1 PF09753.9 KPA38409.1 - 0.27 10.9 8.7 6.6 6.4 8.8 2.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 Synaptobrevin PF00957.21 KPA38409.1 - 0.62 9.9 3.2 0.61 9.9 0.4 2.3 2 0 0 2 2 2 0 Synaptobrevin SNARE PF05739.19 KPA38409.1 - 5.7 7.0 9.0 0.21 11.6 0.5 2.8 4 0 0 4 4 4 0 SNARE domain Amino_oxidase PF01593.24 KPA38410.1 - 3.4e-21 76.1 0.0 1.8e-18 67.1 0.0 2.6 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA38410.1 - 1.8e-10 40.9 0.1 4.2e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA38410.1 - 0.00018 20.9 0.0 0.0075 15.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA38410.1 - 0.0015 18.5 0.0 0.39 10.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KPA38410.1 - 0.0039 16.0 0.0 0.79 8.4 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Prenylcys_lyase PF07156.14 KPA38410.1 - 0.015 14.4 0.0 0.032 13.3 0.0 1.6 1 1 0 1 1 1 0 Prenylcysteine lyase DAO PF01266.24 KPA38410.1 - 0.027 14.0 0.0 0.073 12.6 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase E1-E2_ATPase PF00122.20 KPA38411.1 - 0.035 13.6 1.3 0.086 12.3 0.1 2.1 2 0 0 2 2 2 0 E1-E2 ATPase DUF4992 PF16383.5 KPA38411.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF1929 PF09118.11 KPA38412.1 - 1.8e-26 92.2 0.6 3.6e-26 91.3 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 KPA38412.1 - 1.1e-22 80.5 0.7 3e-22 79.1 0.7 1.8 1 0 0 1 1 1 1 F5/8 type C domain Kelch_6 PF13964.6 KPA38412.1 - 7.9e-13 48.2 7.8 0.00049 20.3 0.2 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KPA38412.1 - 7.8e-11 41.4 3.3 5e-06 26.0 0.2 4.7 4 1 0 4 4 4 3 Kelch motif Glyoxal_oxid_N PF07250.11 KPA38412.1 - 7.2e-06 25.4 0.8 0.0079 15.4 0.4 2.6 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_4 PF13418.6 KPA38412.1 - 8.9e-06 25.6 10.5 0.02 14.9 0.1 4.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KPA38412.1 - 0.00029 20.7 9.0 0.34 11.0 0.2 5.2 6 0 0 6 6 6 2 Kelch motif Aldedh PF00171.22 KPA38414.1 - 3.4e-147 490.7 0.0 3.9e-147 490.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PAN_4 PF14295.6 KPA38415.1 - 1.7e-05 24.6 1.9 3.9e-05 23.5 1.9 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KPA38415.1 - 0.0039 17.1 1.6 0.0039 17.1 1.6 2.2 2 0 0 2 2 2 1 PAN domain MANEC PF07502.14 KPA38415.1 - 0.0048 17.1 4.6 0.011 16.0 4.6 1.5 1 0 0 1 1 1 1 MANEC domain Rhodanese PF00581.20 KPA38416.1 - 0.00012 22.5 0.0 0.00021 21.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain SBF PF01758.16 KPA38417.1 - 1.9e-53 181.1 10.5 1.9e-53 181.1 10.5 2.6 2 2 1 3 3 3 1 Sodium Bile acid symporter family MctB PF11382.8 KPA38417.1 - 2.7 7.6 4.6 5.1 6.7 0.1 2.2 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB bZIP_1 PF00170.21 KPA38418.1 - 0.011 15.8 8.8 0.031 14.4 8.9 1.7 1 1 0 1 1 1 0 bZIP transcription factor Taxilin PF09728.9 KPA38418.1 - 0.014 14.6 2.9 0.02 14.1 2.9 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF782 PF05614.11 KPA38418.1 - 0.076 13.4 0.1 2.5 8.5 0.0 2.4 1 1 1 2 2 2 0 Circovirus protein of unknown function (DUF782) p450 PF00067.22 KPA38419.1 - 1.1e-51 176.0 0.0 1.5e-51 175.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hydrolase_4 PF12146.8 KPA38421.1 - 0.0012 18.1 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA38421.1 - 0.029 15.0 0.0 0.037 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family HET PF06985.11 KPA38422.1 - 3e-31 108.8 0.0 5.4e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HRDC PF00570.23 KPA38422.1 - 0.078 13.0 0.4 34 4.5 0.0 3.3 3 0 0 3 3 3 0 HRDC domain GFO_IDH_MocA PF01408.22 KPA38423.1 - 1.3e-26 93.8 0.0 2.1e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPA38423.1 - 6.5e-15 55.2 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.19 KPA38423.1 - 0.047 13.1 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain G6PD_N PF00479.22 KPA38423.1 - 0.069 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain IlvN PF07991.12 KPA38423.1 - 0.1 12.2 0.0 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ABC-3 PF00950.17 KPA38423.1 - 0.21 11.1 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 ABC 3 transport family DUF953 PF06110.11 KPA38424.1 - 2.1e-14 53.2 0.0 2.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 KPA38424.1 - 0.0031 17.5 0.1 0.0087 16.0 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KPA38424.1 - 0.0088 16.3 0.1 0.58 10.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KPA38424.1 - 0.03 14.1 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.21 KPA38424.1 - 0.042 13.8 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family GFO_IDH_MocA PF01408.22 KPA38425.1 - 3.2e-18 66.7 0.2 5.6e-18 65.9 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KPA38425.1 - 0.018 15.7 0.3 0.036 14.7 0.3 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ParG PF09274.10 KPA38425.1 - 0.07 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 ParG Fungal_trans PF04082.18 KPA38426.1 - 0.00026 20.1 0.3 0.00047 19.3 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 KPA38427.1 - 1.9e-68 230.8 0.0 2.5e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 KPA38428.1 - 1.2e-21 76.6 1.3 3.4e-21 75.2 1.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA38428.1 - 2.6e-20 72.7 0.2 3.9e-20 72.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA38428.1 - 7.7e-07 30.2 0.3 1.3e-06 29.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zf_RING PF16744.5 KPA38428.1 - 0.054 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger LpxI_N PF17930.1 KPA38428.1 - 0.12 12.3 0.5 19 5.2 0.1 2.3 2 0 0 2 2 2 0 LpxI N-terminal domain zf_PR_Knuckle PF18445.1 KPA38428.1 - 0.19 11.6 0.3 0.47 10.3 0.3 1.6 1 0 0 1 1 1 0 PR zinc knuckle motif Varsurf_PPLC PF03490.13 KPA38429.1 - 0.00013 21.8 0.1 0.00029 20.7 0.1 1.5 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C Delta_lysin PF05372.11 KPA38429.1 - 0.04 13.2 0.2 0.081 12.2 0.2 1.5 1 0 0 1 1 1 0 Delta lysin family DUF4064 PF13273.6 KPA38430.1 - 0.0015 18.8 0.5 0.0015 18.8 0.5 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF4064) 3Beta_HSD PF01073.19 KPA38434.1 - 6.2e-13 48.4 0.0 6.8e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPA38434.1 - 8.3e-13 48.3 0.0 9.2e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA38434.1 - 1.3e-11 44.5 0.0 1.4e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KPA38434.1 - 1.5e-09 38.0 0.0 1.8e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPA38434.1 - 5.6e-06 26.1 0.0 6.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KPA38434.1 - 2.1e-05 23.8 0.2 9.5e-05 21.7 0.2 1.8 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 KPA38434.1 - 0.00023 21.1 0.0 0.00057 19.8 0.0 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA38434.1 - 0.0016 17.6 0.0 0.0018 17.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KPA38435.1 - 9.7e-20 70.9 0.0 1.5e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA38435.1 - 1e-15 58.0 0.0 1.3e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA38435.1 - 5.1e-06 26.5 0.0 6.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA38435.1 - 2.1e-05 24.1 0.0 2.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPA38435.1 - 0.022 14.6 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KPA38435.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_transf_54 PF04666.13 KPA38438.1 - 1.9e-08 33.6 0.1 0.0017 17.3 0.0 2.4 2 0 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glucos_trans_II PF14264.6 KPA38438.1 - 0.0064 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Glucosyl transferase GtrII NdhL PF10716.9 KPA38438.1 - 0.011 15.7 0.3 0.025 14.5 0.3 1.5 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit SdpI PF13630.6 KPA38438.1 - 1.4 9.1 3.5 0.39 10.9 0.5 1.6 2 0 0 2 2 2 0 SdpI/YhfL protein family MFS_1 PF07690.16 KPA38440.1 - 2.5e-22 79.3 44.4 2.1e-13 49.9 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.21 KPA38441.1 - 1.7e-21 76.5 0.0 2.1e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aldedh PF00171.22 KPA38442.1 - 2.3e-182 606.6 0.0 2.6e-182 606.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1338 PF07063.13 KPA38443.1 - 2.5e-113 378.6 0.0 2.9e-113 378.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Ribonuc_L-PSP PF01042.21 KPA38444.1 - 5.9e-16 58.6 0.0 7.1e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sulfate_transp PF00916.20 KPA38445.1 - 1.1e-105 353.6 21.9 1.4e-105 353.2 21.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KPA38445.1 - 1.4e-08 34.3 0.0 6.1e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 KPA38445.1 - 0.79 10.2 24.4 0.029 14.8 4.4 3.4 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily SafA PF17073.5 KPA38445.1 - 9.9 6.2 7.5 4.3 7.4 0.0 3.3 3 1 1 4 4 4 0 Two-component-system connector protein Rad60-SLD_2 PF13881.6 KPA38446.1 - 6.8e-12 45.5 0.0 1.7e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KPA38446.1 - 0.00025 21.6 0.8 0.00054 20.5 0.0 1.8 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KPA38446.1 - 0.00029 20.5 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UMP1 PF05348.11 KPA38447.1 - 7.6e-46 155.2 0.0 9.1e-46 154.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.27 KPA38448.1 - 3.8e-24 85.7 0.0 1.1e-10 42.2 0.0 3.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KPA38448.1 - 1.6e-09 38.0 0.1 0.0026 17.6 0.1 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KPA38448.1 - 2.3e-06 28.3 0.3 0.059 13.9 0.2 2.3 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KPA38448.1 - 3.4e-06 27.2 0.0 0.0028 17.9 0.1 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KPA38448.1 - 2.5e-05 23.9 0.0 0.17 11.6 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 KPA38448.1 - 0.00077 19.2 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KPA38448.1 - 0.0037 17.4 0.0 2.8 8.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KPA38448.1 - 0.0041 17.4 0.1 2.7 8.3 0.0 3.0 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 KPA38448.1 - 0.0066 16.8 0.0 4.3 7.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KPA38448.1 - 0.014 15.8 0.0 2.2 8.7 0.0 2.6 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.6 KPA38448.1 - 0.014 15.9 0.0 5.4 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KPA38448.1 - 0.029 14.2 0.1 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SMC_N PF02463.19 KPA38448.1 - 0.032 13.7 0.1 3.2 7.1 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 KPA38448.1 - 0.045 14.2 0.1 0.96 9.9 0.0 2.9 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KPA38448.1 - 0.046 14.0 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KPA38448.1 - 0.05 13.3 0.2 11 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Ploopntkinase1 PF18748.1 KPA38448.1 - 0.055 13.0 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 AAA_5 PF07728.14 KPA38448.1 - 0.059 13.4 0.0 32 4.5 0.0 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 KPA38448.1 - 0.074 12.4 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF202 PF02656.15 KPA38449.1 - 3.3e-17 62.7 3.9 4.7e-17 62.2 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) HEAT PF02985.22 KPA38451.1 - 0.068 13.5 0.5 1.3 9.5 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat Astro_capsid_p PF12226.8 KPA38451.1 - 0.11 11.6 9.8 0.18 10.9 9.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Arm PF00514.23 KPA38451.1 - 0.16 12.1 5.8 4.4 7.5 0.0 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat U3snoRNP10 PF12397.8 KPA38451.1 - 0.3 11.4 4.7 24 5.3 4.7 3.3 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 BUD22 PF09073.10 KPA38451.1 - 0.53 9.6 7.2 0.85 8.9 7.2 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KPA38451.1 - 8.2 4.5 12.1 16 3.6 12.1 1.4 1 0 0 1 1 1 0 Nop14-like family Mlh1_C PF16413.5 KPA38452.1 - 1.1e-99 333.2 0.0 1.9e-99 332.5 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KPA38452.1 - 2.1e-34 117.7 0.0 3.7e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KPA38452.1 - 3.5e-10 39.8 0.0 7.1e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KPA38452.1 - 2.1e-05 25.0 0.0 5.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zn_clus PF00172.18 KPA38454.1 - 0.14 12.3 0.7 0.23 11.6 0.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Lyase_1 PF00206.20 KPA38456.1 - 4.9e-43 147.7 0.0 1.3e-42 146.3 0.0 1.6 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.9 KPA38456.1 - 1.5e-18 67.1 0.4 1e-17 64.4 0.3 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 KPA38456.1 - 0.034 14.2 0.1 0.069 13.2 0.1 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Glyco_hydro_11 PF00457.17 KPA38457.1 - 4.8e-76 254.3 13.0 5.6e-76 254.1 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF1406 PF07190.11 KPA38457.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1406) FMN_red PF03358.15 KPA38458.1 - 3e-21 75.8 0.0 4.7e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KPA38458.1 - 0.0085 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold GMC_oxred_N PF00732.19 KPA38459.1 - 7.3e-56 189.7 0.1 9.4e-56 189.3 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA38459.1 - 8.1e-37 126.9 0.0 1.5e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KPA38459.1 - 9.2e-06 25.1 0.7 0.013 14.8 0.1 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA38459.1 - 2.5e-05 23.5 0.1 5.7e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KPA38459.1 - 0.00041 20.1 0.1 0.0052 16.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA38459.1 - 0.0026 18.0 0.0 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KPA38459.1 - 0.034 14.4 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 KPA38459.1 - 0.085 11.9 1.7 4.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KPA38459.1 - 0.099 13.2 0.3 7.8 7.1 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA38459.1 - 0.29 10.3 2.1 6 6.0 0.9 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MatE PF01554.18 KPA38461.1 - 3.7e-06 26.7 17.6 0.0034 17.1 1.6 3.8 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 KPA38461.1 - 0.0011 19.1 0.1 0.0011 19.1 0.1 4.0 5 0 0 5 5 5 1 Polysaccharide biosynthesis C-terminal domain Vma12 PF11712.8 KPA38461.1 - 0.56 10.3 1.9 0.66 10.0 0.4 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase HHV6-IE PF03753.13 KPA38462.1 - 0.017 12.6 3.2 0.023 12.2 3.2 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Tub_N PF16322.5 KPA38462.1 - 2.8 8.3 11.1 3.4 8.0 11.1 1.4 1 1 0 1 1 1 0 Tubby N-terminal Dehydratase_hem PF13816.6 KPA38463.1 - 2.4e-87 293.2 0.1 2.8e-87 293.0 0.1 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 KPA38463.1 - 0.018 15.4 0.1 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) Fungal_trans PF04082.18 KPA38464.1 - 1.1e-21 77.0 0.0 1.9e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA38464.1 - 2e-07 31.0 10.3 4.1e-07 30.0 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.22 KPA38465.1 - 1.2e-44 152.7 0.0 1.4e-44 152.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MARVEL PF01284.23 KPA38467.1 - 3.1e-08 33.8 24.7 2.6e-07 30.8 21.8 2.2 1 1 0 1 1 1 1 Membrane-associating domain SARAF PF06682.12 KPA38467.1 - 0.074 12.7 3.0 0.21 11.2 3.0 1.8 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Syndecan PF01034.20 KPA38467.1 - 1.3 8.9 0.0 1.3 8.9 0.0 2.5 4 0 0 4 4 4 0 Syndecan domain ADH_N PF08240.12 KPA38468.1 - 4.6e-30 103.7 1.2 1.7e-29 101.9 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA38468.1 - 1.3e-22 80.1 0.1 2.2e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPA38468.1 - 1.5e-09 37.7 0.5 2.8e-09 36.8 0.5 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KPA38468.1 - 1.5e-05 26.1 0.1 0.00011 23.3 0.1 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KPA38468.1 - 0.0017 17.7 0.6 0.0027 17.0 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KPA38468.1 - 0.0058 15.9 0.0 0.0099 15.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA38468.1 - 0.017 13.9 0.2 0.025 13.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 KPA38468.1 - 0.026 14.1 0.2 0.048 13.2 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Prot_ATP_ID_OB PF16450.5 KPA38468.1 - 0.031 14.2 0.7 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain Pyr_redox PF00070.27 KPA38468.1 - 0.061 13.9 0.2 0.38 11.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Arteri_nsp7a PF16749.5 KPA38468.1 - 0.13 12.4 0.5 0.75 10.0 0.1 2.3 2 0 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha Nipped-B_C PF12830.7 KPA38469.1 - 0.019 14.9 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Sulfotransfer_4 PF17784.1 KPA38470.1 - 6.5e-61 205.9 0.0 7.6e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPA38470.1 - 0.01 16.3 0.4 0.058 13.8 0.3 2.3 1 1 1 2 2 2 0 Sulfotransferase family E1-E2_ATPase PF00122.20 KPA38471.1 - 2.9e-36 124.7 21.0 2.6e-31 108.6 0.4 3.8 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KPA38471.1 - 8.7e-22 77.7 5.7 8.7e-22 77.7 5.7 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KPA38471.1 - 1.8e-19 69.6 0.0 3.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPA38471.1 - 3.3e-18 66.8 0.1 1.5e-16 61.3 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPA38471.1 - 1e-14 53.9 0.0 5e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPA38471.1 - 0.00056 19.7 0.7 0.0011 18.8 0.3 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4440 PF14534.6 KPA38473.1 - 6.8e-06 26.4 0.0 8.4e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Dimer_Tnp_Tn5 PF02281.16 KPA38475.1 - 0.22 11.3 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain Clr5 PF14420.6 KPA38475.1 - 0.35 11.1 1.2 17 5.7 1.2 2.2 1 1 0 1 1 1 0 Clr5 domain p450 PF00067.22 KPA38476.1 - 1.6e-53 182.1 0.0 2.4e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.6 KPA38476.1 - 1.5e-20 73.2 1.6 3.8e-20 71.9 1.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.22 KPA38477.1 - 1.1e-35 123.3 0.0 4.6e-35 121.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Terminase_3C PF17288.2 KPA38477.1 - 0.1 13.0 0.0 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 Terminase RNAseH like domain Cupin_2 PF07883.11 KPA38478.1 - 2.6e-06 27.0 0.6 4.5e-06 26.3 0.6 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KPA38478.1 - 2.8e-06 27.0 0.1 4.1e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 KPA38478.1 - 0.0015 18.3 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 KPA38478.1 - 0.019 15.1 0.1 0.027 14.7 0.1 1.2 1 0 0 1 1 1 0 ARD/ARD' family Arabinose_Isome PF02610.15 KPA38478.1 - 0.047 12.9 0.1 0.066 12.4 0.1 1.1 1 0 0 1 1 1 0 L-arabinose isomerase Fasciclin PF02469.22 KPA38479.1 - 5.3e-48 162.4 2.3 1.5e-27 96.4 0.3 2.1 2 0 0 2 2 2 2 Fasciclin domain Cyclin_C_2 PF16899.5 KPA38480.1 - 6.1e-32 110.1 0.0 5.1e-31 107.2 0.0 2.2 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KPA38480.1 - 0.052 13.3 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain BAR PF03114.18 KPA38481.1 - 9.7e-55 185.8 8.2 1.1e-54 185.6 8.2 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KPA38481.1 - 9.4e-07 28.2 3.9 1.3e-06 27.8 3.9 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Arfaptin PF06456.13 KPA38481.1 - 0.55 9.8 9.3 0.16 11.5 5.9 1.8 2 1 0 2 2 2 0 Arfaptin-like domain Tannase PF07519.11 KPA38482.1 - 4.4e-101 339.1 0.3 5.5e-101 338.8 0.3 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KPA38482.1 - 0.0018 17.6 0.0 0.071 12.4 0.0 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA38482.1 - 0.0023 17.6 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA38482.1 - 0.0026 17.3 0.3 0.23 10.9 0.1 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family AAA_11 PF13086.6 KPA38483.1 - 4.9e-24 85.5 0.0 9.4e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPA38483.1 - 4.1e-09 36.4 0.1 0.00019 21.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KPA38483.1 - 3.8e-08 33.8 0.0 0.00011 22.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KPA38483.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KPA38483.1 - 0.059 13.2 0.1 0.64 9.8 0.0 2.3 2 0 0 2 2 2 0 Helicase DEAD PF00270.29 KPA38483.1 - 0.13 12.0 0.1 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 KPA38483.1 - 0.16 11.6 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT_N PF17100.5 KPA38484.1 - 8.5e-06 25.8 0.2 1.6e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase DUF3350 PF11830.8 KPA38484.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) APH PF01636.23 KPA38485.1 - 2.4e-09 37.5 0.1 7.1e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family CAP59_mtransfer PF11735.8 KPA38485.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 DUF366 PF04017.12 KPA38487.1 - 0.0015 18.1 0.1 0.066 12.7 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF366) Dimer_Tnp_hAT PF05699.14 KPA38488.1 - 4.1e-21 74.6 0.3 4.3e-20 71.3 0.1 2.7 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KPA38488.1 - 0.00047 20.5 0.1 0.0014 18.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) zf-BED PF02892.15 KPA38488.1 - 0.0085 16.1 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 BED zinc finger PyrI_C PF02748.15 KPA38488.1 - 0.041 13.8 0.6 0.11 12.5 0.6 1.7 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF659 PF04937.15 KPA38488.1 - 0.041 13.7 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Sugar_tr PF00083.24 KPA38489.1 - 2.8e-91 306.7 27.5 3.4e-91 306.4 27.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38489.1 - 1.1e-14 54.2 27.0 1.1e-14 54.2 27.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Podoplanin PF05808.11 KPA38491.1 - 3.3e-07 30.6 0.1 5.5e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.6 KPA38491.1 - 0.087 12.6 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) VSP PF03302.13 KPA38491.1 - 0.16 10.8 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein SNF2_N PF00176.23 KPA38492.1 - 1.4e-64 218.0 0.1 2.1e-64 217.4 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA38492.1 - 6.1e-10 39.4 0.1 8.8e-09 35.7 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPA38492.1 - 8.3e-08 32.2 0.0 2.3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KPA38492.1 - 1.8e-07 31.3 0.0 1.8e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KPA38492.1 - 0.00036 20.3 2.1 0.00079 19.3 2.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPA38492.1 - 0.0017 18.3 5.8 0.0033 17.3 5.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KPA38492.1 - 0.0025 17.7 5.3 0.0052 16.6 5.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KPA38492.1 - 0.0097 15.9 5.1 0.028 14.4 5.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger SSFA2_C PF14723.6 KPA38492.1 - 0.022 14.7 0.0 0.075 12.9 0.0 1.9 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus RsgA_GTPase PF03193.16 KPA38492.1 - 0.023 14.6 1.0 4.1 7.3 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase zf-C3HC4_2 PF13923.6 KPA38492.1 - 0.026 14.3 5.0 0.03 14.1 3.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA38492.1 - 0.034 14.5 6.5 0.077 13.3 6.5 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 KPA38492.1 - 0.085 12.7 4.6 0.19 11.6 4.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPA38492.1 - 0.2 11.9 5.0 0.49 10.6 5.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FYVE_2 PF02318.16 KPA38492.1 - 9.6 6.4 8.0 0.57 10.4 1.2 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Med8 PF10232.9 KPA38493.1 - 0.074 12.6 2.7 0.098 12.2 0.6 1.9 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Glyco_transf_28 PF03033.20 KPA38494.1 - 4.2e-16 59.3 0.0 1.1e-15 57.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KPA38494.1 - 2.6e-05 23.2 0.2 4e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Epimerase PF01370.21 KPA38495.1 - 5.4e-13 49.0 0.0 8e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KPA38495.1 - 3.5e-07 30.0 0.0 2.1e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KPA38495.1 - 3e-05 24.0 0.0 5.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KPA38495.1 - 0.00024 20.3 0.0 0.16 11.1 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 KPA38495.1 - 0.00052 19.1 0.1 0.56 9.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KPA38495.1 - 0.0019 17.6 0.0 0.051 13.0 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KPA38495.1 - 0.0024 17.3 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase SNF PF00209.18 KPA38498.1 - 4.1e-63 213.9 20.4 2e-33 115.9 6.0 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family DUF3810 PF12725.7 KPA38498.1 - 0.013 14.9 0.6 0.013 14.9 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Cation_ATPase_C PF00689.21 KPA38498.1 - 4.3 7.0 8.7 0.63 9.7 1.2 3.0 3 1 1 4 4 4 0 Cation transporting ATPase, C-terminus MIS13 PF08202.11 KPA38499.1 - 9.9e-58 195.8 1.1 9.9e-58 195.8 1.1 1.8 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Trypan_PARP PF05887.11 KPA38499.1 - 1.3 9.0 25.5 0.14 12.2 11.8 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) ZapB PF06005.12 KPA38499.1 - 3.7 8.1 10.3 1.3 9.5 1.8 3.3 2 1 1 3 3 3 0 Cell division protein ZapB BTB PF00651.31 KPA38501.1 - 0.0017 18.5 0.0 0.0038 17.4 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain BAH PF01426.18 KPA38502.1 - 3.4e-07 30.2 0.1 7.1e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KPA38502.1 - 0.023 14.6 4.1 0.073 13.0 4.1 1.9 1 0 0 1 1 1 0 PHD-finger DnaJ PF00226.31 KPA38503.1 - 6.8e-18 64.6 0.3 1.8e-17 63.2 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 KPA38504.1 - 4.8e-18 65.5 0.0 1.8e-17 63.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA38504.1 - 1.4e-07 31.1 0.0 2.9e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KPA38507.1 - 1e-28 99.7 0.0 3.1e-14 53.3 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA38507.1 - 1.7e-24 85.8 1.0 1.4e-08 35.1 0.0 5.2 3 1 3 6 6 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KPA38507.1 - 2.4e-20 72.0 0.4 1.7e-05 25.1 0.0 6.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 KPA38507.1 - 1.5e-17 61.9 0.0 7.3e-05 22.9 0.0 5.8 5 0 0 5 5 4 3 Ankyrin repeat Ank_5 PF13857.6 KPA38507.1 - 1.1e-14 54.3 0.6 1.1e-07 31.9 0.0 3.9 3 2 1 4 4 3 2 Ankyrin repeats (many copies) NACHT_sigma PF17106.5 KPA38507.1 - 3.9e-09 36.5 11.2 6.6e-09 35.8 11.2 1.4 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases NACHT PF05729.12 KPA38507.1 - 6.5e-09 35.9 0.6 2.4e-08 34.1 0.6 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPA38507.1 - 3.8e-08 33.9 0.0 1e-07 32.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA38507.1 - 0.0003 21.1 0.0 0.0029 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPA38507.1 - 0.0058 16.4 0.3 0.019 14.7 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 KPA38507.1 - 0.0097 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KPA38507.1 - 0.016 15.6 0.0 4.2 7.8 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KPA38507.1 - 0.018 15.4 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KPA38507.1 - 0.034 13.9 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KPA38507.1 - 0.035 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KPA38507.1 - 0.036 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KPA38507.1 - 0.048 14.2 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KPA38507.1 - 0.052 12.7 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 KPA38507.1 - 0.069 12.4 0.0 2.1 7.5 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain HflK_N PF12221.8 KPA38507.1 - 0.19 11.8 0.8 0.51 10.4 0.8 1.7 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Fungal_trans PF04082.18 KPA38508.1 - 5.8e-06 25.5 0.0 7.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Chlorophyllase2 PF12740.7 KPA38509.1 - 5.1e-07 28.9 0.0 7.9e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 KPA38509.1 - 5.6e-06 25.1 0.2 0.058 11.9 0.0 2.3 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.11 KPA38509.1 - 3.6e-05 22.9 0.0 5.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.7 KPA38509.1 - 0.00097 19.8 0.1 0.0021 18.7 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KPA38509.1 - 0.023 14.2 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S9 PF00326.21 KPA38509.1 - 0.026 14.0 0.0 0.073 12.5 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KPA38509.1 - 0.038 13.6 0.0 0.2 11.3 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 KPA38509.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.25 KPA38509.1 - 0.093 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 KPA38509.1 - 0.094 12.0 0.0 0.48 9.6 0.0 2.1 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Lactamase_B PF00753.27 KPA38510.1 - 0.0078 16.2 0.6 0.018 15.0 0.6 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF829 PF05705.14 KPA38511.1 - 2.8e-17 63.4 0.0 3.3e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Pyr_redox_3 PF13738.6 KPA38512.1 - 1.9e-18 66.7 0.3 9.8e-16 57.9 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA38512.1 - 6.6e-16 58.4 0.0 4.1e-13 49.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPA38512.1 - 1.4e-12 46.8 0.2 5.1e-11 41.7 0.1 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPA38512.1 - 3.1e-11 43.0 0.1 8.5e-09 35.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KPA38512.1 - 5.8e-07 29.1 0.0 0.00018 20.9 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KPA38512.1 - 2.2e-06 27.8 0.0 2.3e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPA38512.1 - 5.6e-05 23.6 0.2 0.17 12.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KPA38512.1 - 0.00015 21.2 0.1 0.02 14.3 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SnoaL_2 PF12680.7 KPA38512.1 - 0.001 19.7 0.1 0.013 16.2 0.0 2.5 2 0 0 2 2 2 1 SnoaL-like domain HI0933_like PF03486.14 KPA38512.1 - 0.0014 17.4 0.4 0.0073 15.0 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.20 KPA38512.1 - 0.0036 17.4 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KPA38512.1 - 0.0037 16.6 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KPA38512.1 - 0.0062 15.7 0.7 0.012 14.7 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KPA38512.1 - 0.0077 16.1 0.6 0.29 11.0 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KPA38512.1 - 0.0081 16.4 0.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain tRNA-synt_His PF13393.6 KPA38512.1 - 0.025 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF1348 PF07080.11 KPA38512.1 - 0.044 13.7 0.1 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1348) NAD_binding_7 PF13241.6 KPA38512.1 - 0.046 14.2 0.1 2.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding NTF2 PF02136.20 KPA38512.1 - 0.049 14.2 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Thi4 PF01946.17 KPA38512.1 - 0.049 12.9 0.0 0.37 10.0 0.0 2.1 2 0 0 2 2 2 0 Thi4 family SnoaL_4 PF13577.6 KPA38512.1 - 0.058 13.5 0.1 1.9 8.6 0.0 3.0 2 2 0 2 2 2 0 SnoaL-like domain LEH PF07858.12 KPA38512.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain GIDA PF01134.22 KPA38512.1 - 0.092 11.8 4.3 0.24 10.4 0.7 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A IlvN PF07991.12 KPA38512.1 - 0.097 12.2 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 KPA38512.1 - 0.16 11.0 0.0 0.38 9.7 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 KPA38512.1 - 0.16 11.6 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Ferritin_2 PF13668.6 KPA38513.1 - 1.4e-14 54.5 0.0 2.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain CYYR1 PF10873.8 KPA38513.1 - 1.6 9.2 4.6 3.7 8.0 4.6 1.6 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Hemerythrin PF01814.23 KPA38514.1 - 0.00049 20.7 1.7 0.0014 19.3 1.7 1.8 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain TBCA PF02970.16 KPA38514.1 - 0.094 13.1 1.1 0.16 12.3 1.0 1.4 1 1 0 1 1 1 0 Tubulin binding cofactor A P5CR_dimer PF14748.6 KPA38515.1 - 2.2e-37 127.5 0.2 5.3e-37 126.2 0.2 1.7 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KPA38515.1 - 5e-19 68.7 0.5 1.1e-18 67.5 0.5 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KPA38515.1 - 0.0014 18.7 1.2 0.011 15.7 1.2 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PDH PF02153.17 KPA38515.1 - 0.0036 16.4 0.0 0.0055 15.7 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase Shikimate_DH PF01488.20 KPA38515.1 - 0.0059 16.7 0.3 0.023 14.7 0.2 2.1 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KPA38515.1 - 0.022 14.9 0.1 0.051 13.8 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CoA_binding PF02629.19 KPA38515.1 - 0.073 13.8 0.6 1.8 9.3 0.1 2.8 3 0 0 3 3 3 0 CoA binding domain Cellulase PF00150.18 KPA38516.1 - 6.4e-33 114.4 0.4 9.6e-33 113.8 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zn_clus PF00172.18 KPA38517.1 - 4.2e-09 36.4 6.2 7.9e-09 35.5 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tail_VII PF17091.5 KPA38517.1 - 0.48 10.3 2.6 0.78 9.7 0.1 2.2 2 0 0 2 2 2 0 Inovirus G7P protein Sugar_tr PF00083.24 KPA38518.1 - 1.2e-79 268.4 26.3 1.3e-79 268.2 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38518.1 - 7.4e-23 81.0 41.9 1.7e-17 63.4 29.1 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily EBP PF05241.12 KPA38518.1 - 0.025 14.0 3.8 0.34 10.3 1.2 2.5 2 0 0 2 2 2 0 Emopamil binding protein DUF3042 PF11240.8 KPA38518.1 - 0.25 11.4 1.1 2.9 8.0 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Glyco_hydro_47 PF01532.20 KPA38520.1 - 5.8e-110 368.3 0.0 6.6e-110 368.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 NmrA PF05368.13 KPA38521.1 - 4.5e-40 137.6 0.0 5.3e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA38521.1 - 5.4e-08 32.9 0.0 7.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA38521.1 - 3.6e-06 26.6 0.0 7.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KPA38521.1 - 0.00025 21.5 0.0 0.017 15.6 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KPA38521.1 - 0.0025 17.9 0.0 0.0064 16.6 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KPA38521.1 - 0.0025 16.8 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KPA38521.1 - 0.0036 17.3 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DXP_reductoisom PF02670.16 KPA38521.1 - 0.061 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase ABC_membrane PF00664.23 KPA38522.1 - 8.3e-26 91.2 25.8 4.6e-22 79.0 6.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA38522.1 - 2.9e-21 76.4 0.2 6e-21 75.4 0.2 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KPA38522.1 - 3.8e-06 26.5 1.0 0.086 12.3 0.7 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPA38522.1 - 0.0011 18.9 0.7 0.0091 15.8 0.3 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPA38522.1 - 0.0013 18.5 0.2 0.0031 17.2 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KPA38522.1 - 0.0049 16.8 0.2 0.01 15.8 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 KPA38522.1 - 0.0052 16.0 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Dynamin_N PF00350.23 KPA38522.1 - 0.009 16.1 0.4 0.017 15.1 0.4 1.4 1 0 0 1 1 1 1 Dynamin family AAA_23 PF13476.6 KPA38522.1 - 0.022 15.2 0.4 0.041 14.4 0.4 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KPA38522.1 - 0.031 14.5 0.3 0.11 12.7 0.3 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KPA38522.1 - 0.041 13.6 0.1 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KPA38522.1 - 0.057 13.5 0.3 0.16 12.1 0.3 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-LITAF-like PF10601.9 KPA38525.1 - 2.7e-15 56.4 5.7 3.6e-15 56.0 5.7 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain CpXC PF14353.6 KPA38525.1 - 0.089 12.8 0.3 0.089 12.8 0.3 2.3 2 1 1 3 3 3 0 CpXC protein Lar_restr_allev PF14354.6 KPA38525.1 - 5.6 7.4 7.6 15 6.0 7.6 1.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar Cu-oxidase_2 PF07731.14 KPA38526.1 - 2.7e-46 156.7 6.2 9.9e-42 141.9 0.6 3.5 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 KPA38526.1 - 9.9e-42 141.7 6.4 2.6e-40 137.2 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KPA38526.1 - 7.6e-39 133.4 4.2 1e-35 123.2 0.0 3.7 3 2 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KPA38526.1 - 0.0018 18.3 0.0 0.76 9.9 0.0 3.6 4 1 0 4 4 4 1 Cupredoxin-like domain FTR1 PF03239.14 KPA38527.1 - 1e-79 267.9 5.8 1.2e-79 267.7 5.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Chromo PF00385.24 KPA38528.1 - 7e-07 29.1 5.6 3.2e-05 23.8 0.1 2.4 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain AA_permease_2 PF13520.6 KPA38529.1 - 1.4e-87 294.3 29.8 1.4e-87 294.3 29.8 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA38529.1 - 3.7e-19 68.7 29.8 5.1e-19 68.2 29.8 1.1 1 0 0 1 1 1 1 Amino acid permease CoA_trans PF01144.23 KPA38530.1 - 4.8e-99 330.1 1.7 8.1e-59 198.6 0.1 2.2 2 0 0 2 2 2 2 Coenzyme A transferase Peptidase_M14 PF00246.24 KPA38530.1 - 1.1e-73 248.5 0.0 1.5e-73 248.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AcetylCoA_hyd_C PF13336.6 KPA38530.1 - 0.00046 20.1 0.1 0.0011 19.0 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Propep_M14 PF02244.16 KPA38530.1 - 0.12 12.8 0.1 0.29 11.5 0.1 1.7 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Mito_carr PF00153.27 KPA38532.1 - 1.5e-50 169.1 2.0 6.5e-18 64.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 KPA38533.1 - 0.053 12.5 0.1 0.15 11.0 0.1 1.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.16 KPA38534.1 - 1.2e-07 31.1 17.4 1.7e-07 30.5 17.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KPA38534.1 - 4.9e-07 29.6 1.3 1e-06 28.6 1.3 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MU117 PF15474.6 KPA38535.1 - 2.4e-16 60.4 1.7 2.4e-16 60.4 1.7 1.7 2 0 0 2 2 2 1 Meiotically up-regulated gene family Methyltransf_23 PF13489.6 KPA38535.1 - 3.1e-14 53.2 0.0 4.9e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA38535.1 - 4e-10 40.2 0.0 1.2e-09 38.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA38535.1 - 5.2e-09 36.1 0.0 0.00025 20.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KPA38535.1 - 4.5e-06 27.3 0.0 3.3e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA38535.1 - 5.6e-06 26.9 0.0 1.6e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA38535.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KPA38535.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KPA38535.1 - 0.044 13.3 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.18 KPA38535.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 KPA38535.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase KH_2 PF07650.17 KPA38535.1 - 0.17 11.7 0.1 0.49 10.3 0.1 1.7 2 0 0 2 2 2 0 KH domain PrmA PF06325.13 KPA38535.1 - 0.22 10.9 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Sugar_tr PF00083.24 KPA38536.1 - 8.7e-95 318.2 21.3 1e-94 318.0 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38536.1 - 1.2e-33 116.5 20.1 1.7e-33 116.0 20.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 KPA38537.1 - 9.8e-11 41.6 8.5 2e-10 40.6 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA38537.1 - 6.7e-08 31.9 2.6 1.6e-07 30.6 2.6 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2_C PF02836.17 KPA38539.1 - 1.5e-103 346.1 0.0 1.9e-103 345.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KPA38539.1 - 1.2e-65 221.5 0.0 2.1e-65 220.8 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KPA38539.1 - 6.3e-49 166.1 0.7 3.1e-48 163.9 0.2 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KPA38539.1 - 9.8e-23 80.5 0.9 7.6e-22 77.6 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KPA38539.1 - 4.3e-18 66.0 0.2 1.4e-17 64.4 0.2 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_42 PF02449.15 KPA38539.1 - 0.029 13.7 0.1 0.06 12.7 0.1 1.4 1 0 0 1 1 1 0 Beta-galactosidase DUF2256 PF10013.9 KPA38541.1 - 2.5e-05 24.3 1.2 6.9e-05 22.9 1.2 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYND PF01753.18 KPA38541.1 - 0.048 13.8 2.4 0.16 12.1 2.4 1.9 1 0 0 1 1 1 0 MYND finger zf-C2HC5 PF06221.13 KPA38541.1 - 0.14 12.1 0.5 0.38 10.8 0.5 1.7 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Sulfotransfer_4 PF17784.1 KPA38542.1 - 6e-51 173.3 0.1 7e-51 173.1 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPA38542.1 - 0.0003 21.2 0.6 0.0018 18.7 0.2 1.9 1 1 1 2 2 2 1 Sulfotransferase family FA_desaturase PF00487.24 KPA38543.1 - 1.5 8.6 5.6 3.1 7.6 5.6 1.5 1 0 0 1 1 1 0 Fatty acid desaturase p450 PF00067.22 KPA38544.1 - 7.8e-61 206.2 0.0 9.4e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CpeT PF06206.11 KPA38545.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) DHH PF01368.20 KPA38546.1 - 0.00019 21.6 0.0 0.00032 20.9 0.0 1.4 1 0 0 1 1 1 1 DHH family HAD PF12710.7 KPA38547.1 - 1.8e-06 28.5 0.0 1.5e-05 25.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GxDLY PF14607.6 KPA38547.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type HET PF06985.11 KPA38549.1 - 1.5e-25 90.3 5.1 1.7e-23 83.6 0.2 3.1 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Inhibitor_I66 PF16850.5 KPA38550.1 - 0.0018 18.2 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I66 ketoacyl-synt PF00109.26 KPA38552.1 - 9.5e-68 228.5 0.0 1.6e-67 227.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KPA38552.1 - 5.5e-53 180.1 0.0 8.4e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KPA38552.1 - 2.6e-51 175.0 0.0 4.7e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KPA38552.1 - 4.8e-42 143.9 0.1 2e-28 99.5 0.0 2.8 1 1 1 2 2 2 2 KR domain Ketoacyl-synt_C PF02801.22 KPA38552.1 - 1.7e-33 115.1 0.1 4e-32 110.7 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KPA38552.1 - 3e-19 69.6 0.0 4.7e-18 65.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA38552.1 - 1.3e-12 47.8 0.0 4.1e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA38552.1 - 2.3e-11 44.2 0.0 1.3e-10 41.8 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA38552.1 - 5.4e-11 42.5 0.0 2.6e-10 40.3 0.0 2.2 3 0 0 3 3 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KPA38552.1 - 9.9e-11 42.1 0.6 5.5e-09 36.5 0.6 2.8 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 KPA38552.1 - 7.3e-09 36.2 0.0 3.2e-08 34.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KPA38552.1 - 1.9e-06 28.9 0.1 5.8e-05 24.2 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase BTB PF00651.31 KPA38552.1 - 2e-06 28.0 3.3 1.4e-05 25.3 0.8 3.1 3 0 0 3 3 3 1 BTB/POZ domain NodS PF05401.11 KPA38552.1 - 3.1e-05 23.7 0.0 6.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) adh_short PF00106.25 KPA38552.1 - 0.0001 21.8 0.1 0.034 13.6 0.1 2.7 1 1 1 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 KPA38552.1 - 0.00021 21.1 0.1 0.00045 20.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 KPA38552.1 - 0.00086 19.1 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 KPA38552.1 - 0.0044 16.4 0.2 0.011 15.1 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.26 KPA38552.1 - 0.019 14.9 0.2 0.69 9.9 0.0 3.2 3 0 0 3 3 3 0 Zinc-binding dehydrogenase DREV PF05219.12 KPA38552.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase ACP_syn_III PF08545.10 KPA38552.1 - 0.12 12.2 1.4 0.21 11.4 0.3 2.0 2 0 0 2 2 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AvrM-A PF18241.1 KPA38553.1 - 0.01 16.2 0.4 2.1 8.7 0.2 3.1 3 0 0 3 3 3 0 Flax-rust effector AvrM-A MerR-DNA-bind PF09278.11 KPA38553.1 - 1.4 9.5 8.7 0.28 11.8 4.3 2.2 2 0 0 2 2 2 0 MerR, DNA binding Prefoldin_2 PF01920.20 KPA38554.1 - 6.3e-17 61.5 6.0 7.8e-17 61.2 6.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Mito_carr PF00153.27 KPA38556.1 - 4.8e-53 177.1 3.0 8.2e-18 64.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Dor1 PF04124.12 KPA38557.1 - 1.1e-48 165.7 3.6 1.5e-38 132.4 3.0 2.1 2 0 0 2 2 2 2 Dor1-like family TRAM_LAG1_CLN8 PF03798.16 KPA38558.1 - 1.1e-46 159.1 20.0 1.7e-46 158.5 20.0 1.3 1 0 0 1 1 1 1 TLC domain DUF2721 PF11026.8 KPA38558.1 - 0.23 11.4 1.9 0.24 11.3 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) SH3_1 PF00018.28 KPA38559.1 - 6e-36 121.8 6.3 1.1e-12 47.4 0.2 4.5 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KPA38559.1 - 5.6e-35 119.0 0.0 9.6e-35 118.2 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 KPA38559.1 - 7.1e-34 115.4 9.1 1.2e-10 41.1 0.3 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KPA38559.1 - 1.5e-27 95.0 0.3 7.2e-08 32.0 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.11 KPA38559.1 - 4.3e-05 23.8 28.2 4.3e-05 23.8 28.2 6.9 3 1 2 5 5 5 3 Domain of unknown function (DUF1720) SAM_4 PF18017.1 KPA38559.1 - 0.0001 22.2 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KPA38559.1 - 0.00021 21.3 0.0 0.23 11.6 0.0 3.2 3 0 0 3 3 3 2 SH3 domain SH3_3 PF08239.11 KPA38559.1 - 0.11 12.7 7.1 0.068 13.5 0.7 3.0 3 0 0 3 3 3 0 Bacterial SH3 domain A_deaminase PF00962.22 KPA38560.1 - 2.9e-121 404.8 0.1 3.9e-121 404.4 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.11 KPA38561.1 - 6.8e-92 307.9 14.2 8.4e-92 307.6 14.2 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KPA38561.1 - 0.0088 15.3 10.2 0.02 14.1 10.2 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter DUF4405 PF14358.6 KPA38561.1 - 0.049 14.2 1.4 1.2 9.7 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) EamA PF00892.20 KPA38561.1 - 0.052 13.7 32.0 1.3 9.2 8.0 2.9 2 1 0 2 2 2 0 EamA-like transporter family DUF3096 PF11295.8 KPA38561.1 - 0.45 10.2 3.3 5.4 6.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3096) TMEM234 PF10639.9 KPA38561.1 - 1.3 9.1 10.3 2.1 8.4 2.7 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 WD40 PF00400.32 KPA38562.1 - 1.7e-12 47.7 4.4 0.12 13.3 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA38562.1 - 0.016 15.5 0.1 3 8.2 0.0 3.5 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2020 PF09449.10 KPA38562.1 - 0.05 13.4 0.1 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) Fungal_trans PF04082.18 KPA38565.1 - 0.025 13.6 0.1 0.033 13.2 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans PF04082.18 KPA38566.1 - 3.2e-10 39.5 0.0 7.3e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA38566.1 - 4.1e-05 23.6 6.8 8.5e-05 22.6 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KPA38567.1 - 2.1e-16 60.1 0.4 1.2e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPA38567.1 - 1.5e-07 31.4 0.7 2.3e-07 30.7 0.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA38567.1 - 2.1e-07 31.1 1.1 5.2e-07 29.8 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA38567.1 - 6.1e-07 29.0 0.1 1.1e-06 28.1 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA38567.1 - 5.1e-05 23.8 1.3 0.00015 22.3 1.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA38567.1 - 5.4e-05 22.4 0.1 7e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KPA38567.1 - 0.00011 21.7 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPA38567.1 - 0.00042 19.5 3.8 0.00062 19.0 3.7 1.4 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KPA38567.1 - 0.0026 16.9 1.0 0.004 16.3 1.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KPA38567.1 - 0.0086 15.4 0.2 0.018 14.3 0.1 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KPA38567.1 - 0.011 14.5 1.7 0.019 13.7 1.7 1.4 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KPA38567.1 - 0.026 14.4 1.4 0.055 13.3 1.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KPA38567.1 - 0.044 13.8 0.5 0.078 13.0 0.5 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 KPA38567.1 - 0.059 12.6 0.1 0.059 12.6 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KPA38567.1 - 0.064 12.5 0.2 0.12 11.6 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Rossmann-like PF10727.9 KPA38567.1 - 0.095 12.6 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_2 PF03446.15 KPA38567.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Trp_halogenase PF04820.14 KPA38567.1 - 0.16 10.8 1.7 2.5 6.9 1.5 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TRP PF06011.12 KPA38567.1 - 0.28 9.9 0.1 0.4 9.4 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel SnoaL_4 PF13577.6 KPA38568.1 - 0.00027 21.1 0.0 0.00036 20.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KPA38568.1 - 0.00064 20.3 0.0 0.00082 20.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4099 PF13351.6 KPA38568.1 - 0.068 13.4 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4099) Amidohydro_2 PF04909.14 KPA38569.1 - 6.3e-36 124.6 0.5 8.1e-36 124.3 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase PAN_3 PF08277.12 KPA38570.1 - 0.15 11.9 4.2 0.53 10.1 4.2 2.0 1 0 0 1 1 1 0 PAN-like domain Trypsin_2 PF13365.6 KPA38571.1 - 9.7e-09 36.3 0.0 2.4e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KPA38571.1 - 4.1e-08 33.3 0.0 7.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin Peptidase_C3 PF00548.20 KPA38571.1 - 0.0016 18.4 0.3 0.0031 17.4 0.3 1.4 1 0 0 1 1 1 1 3C cysteine protease (picornain 3C) MFS_1 PF07690.16 KPA38572.1 - 2.1e-24 86.1 37.7 1e-17 64.1 11.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA38572.1 - 2.4e-23 82.8 17.1 1.5e-22 80.1 17.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KPA38572.1 - 0.0053 15.2 1.2 0.0086 14.5 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_8 PF13450.6 KPA38574.1 - 2.9e-12 46.6 0.1 7.7e-12 45.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA38574.1 - 3.4e-08 33.5 0.1 1.3e-06 28.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA38574.1 - 3.4e-06 26.5 0.0 0.00021 20.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPA38574.1 - 8.3e-05 22.0 0.2 0.058 12.7 0.0 3.5 3 1 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KPA38574.1 - 0.00016 20.9 0.0 0.00027 20.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KPA38574.1 - 0.00017 22.1 0.0 0.81 10.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA38574.1 - 0.00038 19.3 0.0 0.029 13.1 0.0 2.8 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.6 KPA38574.1 - 0.00047 20.2 0.0 0.0039 17.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KPA38574.1 - 0.0047 16.0 0.0 0.0071 15.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KPA38574.1 - 0.01 15.1 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KPA38574.1 - 0.023 14.0 0.0 0.053 12.8 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain DUF3452 PF11934.8 KPA38574.1 - 0.034 13.7 0.2 0.089 12.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Shikimate_DH PF01488.20 KPA38574.1 - 0.19 11.8 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Podoplanin PF05808.11 KPA38575.1 - 0.00033 20.8 0.1 0.00068 19.8 0.1 1.5 1 0 0 1 1 1 1 Podoplanin HET PF06985.11 KPA38577.1 - 1.1e-26 94.0 0.0 2.5e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.6 KPA38577.1 - 9.9e-13 48.3 0.1 5.8e-07 29.9 0.1 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KPA38577.1 - 2.4e-07 30.9 0.4 0.0022 18.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KPA38577.1 - 5.3e-07 29.5 0.1 0.004 17.5 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KPA38577.1 - 7.1e-07 29.7 0.0 0.00016 22.2 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA38577.1 - 9.8e-07 28.9 0.1 8.3e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Cutinase PF01083.22 KPA38578.1 - 9.5e-49 165.8 0.0 1.3e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 KPA38578.1 - 0.0011 18.5 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) GATase_3 PF07685.14 KPA38578.1 - 0.037 13.6 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain VirJ PF06057.11 KPA38578.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 KPA38578.1 - 0.2 11.5 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase F-box-like PF12937.7 KPA38579.1 - 5.4e-05 23.0 0.6 0.00019 21.3 0.6 2.0 1 0 0 1 1 1 1 F-box-like NTP_transferase PF00483.23 KPA38581.1 - 5e-53 180.2 0.0 8.5e-53 179.5 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KPA38581.1 - 5.1e-18 64.0 13.3 4.4e-11 42.0 1.9 4.1 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KPA38581.1 - 1.1e-09 38.9 0.0 1.5e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KPA38581.1 - 2.8e-07 30.1 9.3 1.4e-06 27.9 0.6 3.7 4 1 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KPA38581.1 - 9.2e-05 20.8 0.1 0.00019 19.7 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 KPA38581.1 - 0.03 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase IspD PF01128.19 KPA38581.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DND1_DSRM PF14709.7 KPA38582.1 - 0.002 18.4 0.1 0.0034 17.6 0.1 1.4 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KPA38582.1 - 0.0065 17.2 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF755 PF05501.11 KPA38582.1 - 0.97 9.7 9.6 1.3 9.3 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Prenyltrans PF00432.21 KPA38583.1 - 2.2e-37 126.4 23.6 2.7e-07 30.2 0.2 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KPA38583.1 - 0.00079 18.6 0.0 0.32 10.0 0.0 2.3 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain Pkinase PF00069.25 KPA38584.1 - 4.7e-38 131.1 0.0 5.9e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA38584.1 - 3.6e-15 56.0 0.0 4.7e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Abhydrolase_1 PF00561.20 KPA38585.1 - 4.9e-15 55.9 0.1 2.2e-14 53.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA38585.1 - 2.6e-05 23.6 0.0 0.0043 16.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KPA38585.1 - 0.0036 17.1 0.1 0.024 14.4 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KPA38585.1 - 0.082 13.0 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain BTB PF00651.31 KPA38587.1 - 7.3e-15 55.2 0.0 1.6e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SepF PF04472.12 KPA38587.1 - 0.057 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Cell division protein SepF CorA PF01544.18 KPA38588.1 - 3e-08 33.3 1.0 3e-08 33.3 1.0 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein FixP_N PF14715.6 KPA38588.1 - 0.0057 16.4 0.2 0.0057 16.4 0.2 2.3 2 0 0 2 2 2 1 N-terminal domain of cytochrome oxidase-cbb3, FixP Ni_hydr_CYTB PF01292.20 KPA38588.1 - 3.7 7.1 10.9 3.2 7.3 8.4 1.9 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4448 PF14610.6 KPA38589.1 - 0.064 13.0 0.0 0.064 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PspB PF06667.12 KPA38589.1 - 0.077 13.1 0.9 0.15 12.2 0.9 1.5 1 0 0 1 1 1 0 Phage shock protein B TMEM132D_C PF15706.5 KPA38589.1 - 0.085 12.6 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Herpes_gE PF02480.16 KPA38589.1 - 0.14 10.9 0.1 0.13 11.0 0.1 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.6 KPA38589.1 - 0.16 12.2 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.16 KPA38590.1 - 7.3e-39 133.7 55.0 7.3e-39 133.7 55.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA38590.1 - 1.8e-08 33.3 26.7 3.8e-08 32.2 26.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hen1_L PF12623.7 KPA38590.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 PPP1R35_C PF15503.6 KPA38591.1 - 0.14 12.0 1.7 0.3 10.9 1.7 1.5 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus RhoGEF67_u1 PF16615.5 KPA38591.1 - 1.6 9.3 9.2 4.9 7.7 9.2 1.9 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 NDUF_B8 PF05821.11 KPA38592.1 - 2.4e-07 30.8 0.2 3.1e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 KPA38593.1 - 3.4e-65 220.1 0.2 5.9e-65 219.3 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA38593.1 - 3.8e-19 69.1 0.0 4.3e-18 65.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA38593.1 - 2.2e-09 37.5 0.0 5.8e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPA38593.1 - 0.00082 19.2 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KPA38593.1 - 0.011 15.0 0.4 1.3 8.1 0.0 2.8 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 HSA PF07529.13 KPA38593.1 - 0.014 15.7 15.3 0.036 14.4 13.9 2.5 1 1 1 2 2 2 0 HSA SET PF00856.28 KPA38595.1 - 6.3e-14 52.7 0.0 3e-13 50.5 0.0 2.0 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KPA38595.1 - 3.4e-07 30.2 14.3 7.9e-07 29.1 14.3 1.7 1 0 0 1 1 1 1 MYND finger CTD_bind PF04818.13 KPA38596.1 - 3.3e-09 37.4 0.0 6.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KPA38596.1 - 4.5e-06 26.4 0.0 9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TetR_C_20 PF17925.1 KPA38596.1 - 0.19 12.1 0.0 0.57 10.5 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain E1-E2_ATPase PF00122.20 KPA38597.1 - 1.4e-47 161.6 3.9 1.4e-47 161.6 3.9 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KPA38597.1 - 2.6e-17 63.8 0.0 8.1e-17 62.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPA38597.1 - 8.1e-09 35.1 0.0 1.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KPA38597.1 - 0.0084 16.2 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KPA38597.1 - 0.015 15.0 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.32 KPA38598.1 - 0.0035 18.2 0.1 0.62 11.0 0.0 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat WD40_like PF17005.5 KPA38598.1 - 0.037 13.3 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain ADK_lid PF05191.14 KPA38599.1 - 0.24 11.4 4.6 8.8 6.4 0.1 3.4 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2 PF00096.26 KPA38599.1 - 0.33 11.5 0.1 0.33 11.5 0.1 3.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type UPF0506 PF11703.8 KPA38599.1 - 1.3 9.5 12.8 0.49 10.8 6.8 2.9 1 1 1 2 2 2 0 UPF0506 HTH_19 PF12844.7 KPA38600.1 - 0.041 13.9 0.2 0.071 13.1 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Abhydrolase_1 PF00561.20 KPA38602.1 - 5.3e-17 62.3 0.2 9.1e-17 61.5 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA38602.1 - 4.1e-14 53.7 0.0 5.6e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA38602.1 - 5.6e-06 25.8 0.0 9.7e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Sugar_tr PF00083.24 KPA38603.1 - 6.1e-99 331.9 22.0 7.6e-99 331.6 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38603.1 - 4.9e-20 71.7 23.2 4.9e-20 71.7 23.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KPA38603.1 - 0.011 15.5 3.5 0.21 11.4 0.4 2.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LapA_dom PF06305.11 KPA38603.1 - 0.18 11.6 3.1 1.3 8.9 0.1 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain zf-RNPHF PF08080.12 KPA38603.1 - 0.34 10.9 0.9 8.5 6.4 0.2 2.4 2 0 0 2 2 2 0 RNPHF zinc finger Alpha-L-AF_C PF06964.12 KPA38604.1 - 2.3e-22 79.9 0.1 4.1e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KPA38604.1 - 0.11 12.7 2.2 0.38 11.0 0.4 2.5 2 0 0 2 2 2 0 Carbohydrate binding domain AMP-binding PF00501.28 KPA38605.1 - 1.2e-61 208.6 0.0 1.8e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KPA38605.1 - 2.6e-14 53.3 0.1 6.7e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 KPA38605.1 - 7.6e-07 28.6 6.4 0.0028 17.3 0.0 5.9 6 1 0 6 6 6 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KPA38605.1 - 0.015 15.0 15.8 0.91 9.3 1.0 6.7 5 3 1 6 6 6 0 Hexapeptide repeat of succinyl-transferase AMP-binding_C PF13193.6 KPA38605.1 - 0.034 15.1 0.0 3.4 8.7 0.0 3.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KPA38605.1 - 0.056 12.3 0.0 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Aldolase_II PF00596.21 KPA38607.1 - 3.5e-50 170.5 0.1 5.1e-50 170.0 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Glyco_tranf_2_3 PF13641.6 KPA38608.1 - 3.2e-20 73.0 0.0 4.2e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPA38608.1 - 6.2e-10 39.1 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KPA38608.1 - 0.00017 21.1 0.1 0.0056 16.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_hydro_43 PF04616.14 KPA38609.1 - 5.2e-12 45.7 8.2 2.7e-11 43.3 3.3 1.9 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 DUF1533 PF07550.11 KPA38609.1 - 0.11 12.3 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Acetyltransf_7 PF13508.7 KPA38610.1 - 1.6e-09 38.0 0.0 2.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA38610.1 - 2.5e-09 37.4 0.0 3.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA38610.1 - 2.9e-08 33.7 0.0 4.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA38610.1 - 0.0004 20.3 0.0 0.00069 19.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KPA38610.1 - 0.08 13.1 0.0 0.09 12.9 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HET PF06985.11 KPA38611.1 - 6.4e-28 98.0 0.0 9.5e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GATase PF00117.28 KPA38612.1 - 4.8e-05 23.2 0.0 7.9e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF2278 PF10042.9 KPA38612.1 - 0.14 12.1 0.0 1.6 8.7 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2278) CFEM PF05730.11 KPA38613.1 - 1.4e-15 57.2 11.9 2.2e-15 56.5 11.9 1.3 1 0 0 1 1 1 1 CFEM domain DUF998 PF06197.13 KPA38613.1 - 1.2 8.6 9.1 0.22 11.1 4.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF998) Methyltransf_23 PF13489.6 KPA38614.1 - 8.6e-18 64.7 0.0 1.3e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA38614.1 - 7.1e-10 39.5 0.0 1.7e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA38614.1 - 4.1e-09 36.4 0.0 5.5e-08 32.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA38614.1 - 1.2e-06 29.2 0.0 1e-05 26.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA38614.1 - 1.4e-06 28.9 0.0 2.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KPA38614.1 - 0.00069 19.1 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KPA38614.1 - 0.0011 18.6 0.0 0.0032 17.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 KPA38614.1 - 0.052 13.3 0.0 0.61 9.8 0.0 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KPA38614.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KPA38614.1 - 0.15 11.4 0.0 1.9 7.7 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KPA38614.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ysc84 PF04366.12 KPA38617.1 - 6.7e-38 129.3 0.8 1.1e-37 128.7 0.8 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator YjcB PF15940.5 KPA38618.1 - 0.11 12.7 3.1 0.42 10.8 0.1 2.5 1 1 1 2 2 2 0 Family of unknown function DUF3450 PF11932.8 KPA38621.1 - 0.028 13.7 1.9 0.049 12.9 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DMPK_coil PF08826.10 KPA38621.1 - 0.03 14.4 1.0 0.03 14.4 1.0 2.0 2 0 0 2 2 2 0 DMPK coiled coil domain like FlxA PF14282.6 KPA38621.1 - 0.033 14.2 0.2 0.072 13.1 0.2 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF1319 PF07028.11 KPA38621.1 - 0.044 14.0 0.2 0.095 12.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) MRP_L53 PF10780.9 KPA38621.1 - 0.074 13.2 0.3 3.2 8.0 0.1 2.9 1 1 1 2 2 2 0 39S ribosomal protein L53/MRP-L53 APH PF01636.23 KPA38624.1 - 3.4e-13 50.1 0.0 7.8e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Asp PF00026.23 KPA38626.1 - 3.5e-79 266.5 6.4 4.2e-79 266.2 6.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA38626.1 - 2.6e-12 47.3 3.5 4.2e-09 36.9 2.9 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPA38626.1 - 5e-05 23.9 0.6 0.67 10.6 0.3 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KPA38626.1 - 0.17 11.7 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Pepsin-I3 PF06394.13 KPA38627.1 - 0.12 12.6 0.3 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain HET PF06985.11 KPA38628.1 - 1.4e-31 109.8 0.3 2.8e-31 108.8 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cutinase PF01083.22 KPA38629.1 - 5.4e-47 160.0 1.2 7.2e-47 159.6 1.2 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPA38629.1 - 0.00085 18.9 0.4 0.0017 18.0 0.4 1.4 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.25 KPA38629.1 - 0.0074 16.2 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_9 PF10081.9 KPA38629.1 - 0.013 14.7 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF2974 PF11187.8 KPA38629.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) VirJ PF06057.11 KPA38629.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) NACHT_N PF17100.5 KPA38629.1 - 0.097 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Abhydrolase_2 PF02230.16 KPA38629.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PKD_channel PF08016.12 KPA38632.1 - 5.1e-07 28.7 20.8 1.9e-05 23.5 20.8 2.2 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KPA38632.1 - 0.00011 21.5 28.0 0.0016 17.7 28.0 2.1 1 1 0 1 1 1 1 Ion transport protein Macro PF01661.21 KPA38633.1 - 4e-40 136.5 0.2 6.3e-40 135.9 0.2 1.3 1 0 0 1 1 1 1 Macro domain PXT1 PF15214.6 KPA38633.1 - 0.19 12.1 0.7 0.48 10.8 0.1 1.8 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 ABC_tran PF00005.27 KPA38635.1 - 2.5e-48 164.1 0.2 7e-24 84.9 0.0 3.7 2 1 0 2 2 2 2 ABC transporter 4HB PF17947.1 KPA38635.1 - 9.1e-26 89.7 1.1 2.2e-25 88.5 0.2 2.3 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 KPA38635.1 - 5.7e-19 69.0 0.1 0.0018 18.1 0.0 4.9 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPA38635.1 - 3e-17 62.8 0.7 2.7e-05 23.7 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPA38635.1 - 7.7e-09 35.2 0.0 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KPA38635.1 - 3.4e-08 34.2 8.7 0.00048 20.7 0.2 3.2 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KPA38635.1 - 5.2e-08 33.0 0.4 0.00075 19.4 0.0 2.9 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KPA38635.1 - 1.4e-07 31.6 0.0 0.0025 17.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KPA38635.1 - 2.2e-07 31.2 0.0 0.0075 16.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KPA38635.1 - 4.1e-07 30.4 0.2 0.021 15.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 KPA38635.1 - 3.5e-06 27.2 0.0 0.0013 18.8 0.0 2.9 2 1 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 KPA38635.1 - 3.6e-06 27.5 0.1 0.081 13.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 KPA38635.1 - 1.2e-05 25.3 3.5 0.04 13.6 0.0 4.0 5 0 0 5 5 4 2 AAA ATPase domain AAA PF00004.29 KPA38635.1 - 1.7e-05 25.2 0.0 0.62 10.5 0.0 4.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KPA38635.1 - 2.5e-05 24.5 0.0 0.38 10.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KPA38635.1 - 3.3e-05 23.0 0.3 0.23 10.4 0.0 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KPA38635.1 - 5.1e-05 23.7 0.0 0.3 11.5 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 KPA38635.1 - 5.7e-05 23.5 0.0 0.79 10.1 0.0 3.1 2 0 0 2 2 2 2 RNA helicase PduV-EutP PF10662.9 KPA38635.1 - 8.7e-05 22.3 0.1 0.07 12.9 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KPA38635.1 - 0.00025 21.0 0.0 0.093 12.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 KPA38635.1 - 0.00034 20.8 0.0 0.92 9.6 0.0 4.0 4 0 0 4 4 3 1 Helicase HerA, central domain AAA_27 PF13514.6 KPA38635.1 - 0.00051 19.7 0.0 0.37 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KPA38635.1 - 0.00052 19.3 0.1 1.1 8.3 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit AAA_24 PF13479.6 KPA38635.1 - 0.00064 19.5 0.1 1.4 8.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain NB-ARC PF00931.22 KPA38635.1 - 0.0008 18.7 0.2 0.12 11.5 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain AAA_14 PF13173.6 KPA38635.1 - 0.00088 19.3 0.0 3.8 7.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KPA38635.1 - 0.0011 18.6 0.1 1.7 8.2 0.0 3.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KPA38635.1 - 0.0014 18.4 0.0 3 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 KPA38635.1 - 0.0022 18.2 0.0 1.7 8.9 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 KPA38635.1 - 0.0023 17.9 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Septin PF00735.18 KPA38635.1 - 0.0035 16.7 0.6 2 7.6 0.0 3.2 3 0 0 3 3 3 1 Septin ATPase_2 PF01637.18 KPA38635.1 - 0.0048 16.8 0.1 2.4 8.0 0.0 3.3 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea ParcG PF10274.9 KPA38635.1 - 0.0054 16.9 0.4 1.3 9.1 0.1 2.8 1 1 1 3 3 3 1 Parkin co-regulated protein AAA_13 PF13166.6 KPA38635.1 - 0.0074 15.0 0.0 3.8 6.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 KPA38635.1 - 0.0085 15.9 0.0 0.48 10.1 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 KPA38635.1 - 0.0091 15.8 0.1 13 5.5 0.0 3.4 3 0 0 3 3 3 0 Cytidylate kinase ATP_bind_1 PF03029.17 KPA38635.1 - 0.01 15.7 0.0 7.2 6.3 0.0 2.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 KPA38635.1 - 0.011 15.9 0.0 6.8 6.9 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KPA38635.1 - 0.015 14.9 0.0 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region CLP1_P PF16575.5 KPA38635.1 - 0.018 14.9 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 KPA38635.1 - 0.018 14.8 0.0 5.9 6.6 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein HEAT PF02985.22 KPA38635.1 - 0.02 15.1 0.2 22 5.7 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat ATP-synt_ab PF00006.25 KPA38635.1 - 0.043 13.5 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SSE PF00437.20 KPA38635.1 - 0.05 12.7 0.1 4.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KPA38635.1 - 0.053 12.8 0.1 12 5.1 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin Ploopntkinase3 PF18751.1 KPA38635.1 - 0.057 13.3 0.1 11 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Mg_chelatase PF01078.21 KPA38635.1 - 0.062 12.7 0.0 4.4 6.6 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 KPA38635.1 - 0.066 13.1 0.0 15 5.4 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 KPA38635.1 - 0.085 12.4 0.0 8.8 5.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 KPA38635.1 - 0.1 12.4 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal DUF815 PF05673.13 KPA38635.1 - 0.11 11.7 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AA_permease PF00324.21 KPA38636.1 - 1.5e-87 294.2 29.8 1.8e-87 294.0 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA38636.1 - 7.7e-24 84.3 32.9 9.3e-24 84.0 32.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3810 PF12725.7 KPA38636.1 - 2.3 7.5 4.7 3.6 6.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) TPR_8 PF13181.6 KPA38637.1 - 1.9e-07 30.7 4.7 0.058 13.6 0.8 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KPA38637.1 - 1.4e-06 27.8 7.1 0.00053 19.7 1.6 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KPA38637.1 - 2.5e-06 27.2 16.5 0.0032 17.5 1.9 5.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KPA38637.1 - 1.4e-05 25.6 0.3 1.4e-05 25.6 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KPA38637.1 - 1.9e-05 24.2 0.7 0.003 17.2 0.0 4.0 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.6 KPA38637.1 - 5.7e-05 23.5 4.1 0.014 15.9 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KPA38637.1 - 0.0002 21.6 11.9 0.007 16.6 1.3 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KPA38637.1 - 0.004 17.9 0.1 0.004 17.9 0.1 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat DivIVA PF05103.13 KPA38637.1 - 0.32 11.1 5.6 11 6.2 0.4 3.1 3 1 0 3 3 3 0 DivIVA protein TPR_7 PF13176.6 KPA38637.1 - 7.7 6.8 7.1 26 5.1 0.1 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat AMP-binding PF00501.28 KPA38638.1 - 1.4e-300 995.8 0.0 9.1e-83 278.2 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KPA38638.1 - 6.6e-189 628.3 0.0 1.3e-51 175.7 0.0 6.7 5 2 0 5 5 5 5 Condensation domain PP-binding PF00550.25 KPA38638.1 - 6.5e-34 116.1 0.3 2.2e-08 34.3 0.0 5.2 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KPA38638.1 - 6.7e-09 36.6 0.0 0.65 11.0 0.0 4.8 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain AATase PF07247.12 KPA38638.1 - 5e-05 22.1 0.3 0.043 12.4 0.0 2.9 2 0 0 2 2 2 2 Alcohol acetyltransferase DUF5122 PF17164.4 KPA38638.1 - 0.2 12.0 4.9 15 5.9 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller MFS_1 PF07690.16 KPA38639.1 - 2e-40 138.9 44.5 2e-40 138.9 44.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA38639.1 - 1.7e-07 30.1 16.1 3e-07 29.3 16.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KPA38639.1 - 0.053 11.8 17.6 0.28 9.4 13.3 3.2 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.25 KPA38640.1 - 8e-24 84.2 0.0 1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA38640.1 - 9.4e-19 67.9 0.0 1.2e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA38640.1 - 2.3e-05 24.4 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPA38640.1 - 0.0024 17.8 0.1 0.0043 17.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA38640.1 - 0.019 14.4 0.1 0.25 10.8 0.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Phe_hydrox_dim PF07976.12 KPA38642.1 - 1.1e-20 74.3 0.0 2.4e-20 73.2 0.0 1.6 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DUF1236 PF06823.12 KPA38642.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1236) FAD_binding_3 PF01494.19 KPA38642.1 - 0.16 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Prok-RING_4 PF14447.6 KPA38643.1 - 9.5e-05 22.2 2.0 0.0012 18.6 0.1 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KPA38643.1 - 0.00073 19.5 0.3 0.0023 17.9 0.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPA38643.1 - 0.0012 18.7 3.3 0.006 16.5 2.5 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KPA38643.1 - 0.03 14.2 1.3 0.11 12.4 1.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA38643.1 - 0.05 13.4 2.6 0.052 13.4 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA38643.1 - 0.15 12.4 2.2 0.47 10.8 0.2 2.2 2 0 0 2 2 2 0 Ring finger domain Prok-RING_1 PF14446.6 KPA38643.1 - 1.6 8.7 7.4 0.25 11.3 0.7 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 LupA PF18242.1 KPA38644.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Legionella ubiquitin-specific protease A domain Curto_V2 PF07325.11 KPA38645.1 - 0.11 12.3 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Curtovirus V2 protein Lzipper-MIP1 PF14389.6 KPA38646.1 - 0.0025 18.1 7.0 0.0025 18.1 7.0 3.0 1 1 1 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Golgin_A5 PF09787.9 KPA38646.1 - 0.043 13.3 15.7 0.1 12.0 15.7 1.7 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 KPA38646.1 - 0.085 12.2 13.0 0.17 11.2 13.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 KPA38646.1 - 0.092 11.3 11.2 0.11 11.0 11.2 1.1 1 0 0 1 1 1 0 Macoilin family Exonuc_VII_L PF02601.15 KPA38646.1 - 0.28 10.7 15.0 0.05 13.2 11.1 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit CREPT PF16566.5 KPA38646.1 - 1.2 9.3 16.1 0.7 10.0 8.1 2.5 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour BLOC1_2 PF10046.9 KPA38646.1 - 2.4 8.5 8.7 0.43 10.9 4.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 betaPIX_CC PF16523.5 KPA38646.1 - 6.6 6.6 14.3 4.9 7.1 3.9 2.7 1 1 1 2 2 2 0 betaPIX coiled coil RTA1 PF04479.13 KPA38647.1 - 8.5e-51 172.5 5.3 1.3e-50 171.9 5.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Tetraspanin PF00335.20 KPA38647.1 - 0.054 13.2 1.7 0.076 12.7 0.4 1.8 1 1 0 1 1 1 0 Tetraspanin family DUF373 PF04123.13 KPA38647.1 - 0.62 9.4 5.3 0.73 9.2 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) 60KD_IMP PF02096.20 KPA38647.1 - 1 9.2 6.3 0.31 10.9 2.5 1.9 2 1 0 2 2 2 0 60Kd inner membrane protein DUF996 PF06195.13 KPA38647.1 - 4.7 7.5 13.8 49 4.2 10.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF996) DUF111 PF01969.17 KPA38648.1 - 0.024 13.8 0.4 0.029 13.5 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF111 Mucin PF01456.17 KPA38648.1 - 3.1 7.8 18.4 4.7 7.2 18.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PEX11 PF05648.14 KPA38649.1 - 0.00078 19.0 0.1 0.003 17.1 0.0 1.9 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) Mito_carr PF00153.27 KPA38650.1 - 7.2e-38 128.4 1.0 2.1e-15 56.4 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPA38650.1 - 2.6e-05 23.6 0.3 6.1e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Gammaproteobacterial serine protease Fungal_trans PF04082.18 KPA38651.1 - 2.5e-10 39.9 0.0 3.9e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DJ-1_PfpI PF01965.24 KPA38652.1 - 1.5e-07 31.4 0.0 4e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KPA38652.1 - 0.13 12.0 0.0 0.43 10.2 0.0 1.7 1 1 1 2 2 2 0 ThiJ/PfpI family-like IPTL-CTERM PF18203.1 KPA38653.1 - 1.9 8.5 4.6 3.3 7.7 4.6 1.4 1 0 0 1 1 1 0 IPTL-CTERM motif F-box-like PF12937.7 KPA38657.1 - 0.049 13.5 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 F-box-like SAM_DrpA PF18255.1 KPA38657.1 - 0.11 12.8 0.1 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 DNA processing protein A sterile alpha motif domain DUF2273 PF10031.9 KPA38659.1 - 0.035 14.1 3.6 0.035 14.1 3.6 1.9 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF2439 PF10382.9 KPA38663.1 - 2.6e-26 91.7 0.0 4.7e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Zn_clus PF00172.18 KPA38664.1 - 0.55 10.4 9.0 1.1 9.4 9.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.23 KPA38665.1 - 3.1e-19 68.7 0.0 1.5e-18 66.5 0.0 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KPA38665.1 - 5.4e-15 55.3 0.0 1.9e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 KPA38665.1 - 0.0034 17.4 3.1 0.028 14.5 0.0 3.1 3 0 0 3 3 3 1 Bd3614-like deaminase SCHIP-1 PF10148.9 KPA38665.1 - 0.36 10.4 8.8 0.59 9.7 8.8 1.3 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Macoilin PF09726.9 KPA38665.1 - 1.3 7.5 7.9 1.7 7.1 7.9 1.1 1 0 0 1 1 1 0 Macoilin family Suf PF05843.14 KPA38665.1 - 4.9 7.1 6.6 7.6 6.4 6.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Abhydrolase_6 PF12697.7 KPA38666.1 - 0.0006 20.5 0.2 0.0014 19.3 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA38666.1 - 0.022 14.4 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_1 PF00232.18 KPA38667.1 - 7.5e-145 482.8 0.0 8.6e-145 482.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.8 KPA38667.1 - 0.0014 18.2 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core VitD-bind_III PF09164.10 KPA38667.1 - 0.16 12.0 0.0 7.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Sugar_tr PF00083.24 KPA38668.1 - 8.6e-79 265.5 26.0 1e-78 265.2 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38668.1 - 2.1e-21 76.2 48.8 9.4e-19 67.5 20.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA38668.1 - 3.4e-05 22.5 2.0 3.4e-05 22.5 2.0 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KPA38669.1 - 4.2e-11 42.4 0.8 9.6e-09 34.6 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA38669.1 - 4.8e-07 29.8 8.8 1.1e-06 28.6 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAN_4 PF14295.6 KPA38671.1 - 0.00035 20.4 1.4 0.0011 18.9 1.4 1.8 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 KPA38671.1 - 0.041 13.7 0.9 0.041 13.7 0.9 2.2 2 0 0 2 2 2 0 PAN-like domain Methyltransf_23 PF13489.6 KPA38673.1 - 5.1e-23 81.7 0.0 8e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA38673.1 - 5.6e-15 55.8 0.0 1.2e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA38673.1 - 5e-12 46.3 0.0 1.1e-11 45.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA38673.1 - 2.6e-11 43.5 0.0 2.5e-10 40.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA38673.1 - 4.2e-09 37.0 0.0 1.4e-08 35.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA38673.1 - 4.2e-06 26.3 0.0 3.8e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPA38673.1 - 0.00022 20.8 0.0 0.00051 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KPA38673.1 - 0.00028 21.1 0.0 0.00041 20.5 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KPA38673.1 - 0.00097 18.6 0.0 0.0022 17.5 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KPA38673.1 - 0.0039 16.6 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KPA38673.1 - 0.014 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase TehB PF03848.14 KPA38673.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB ETRAMP PF09716.10 KPA38675.1 - 0.3 11.2 1.6 0.69 10.0 0.1 1.9 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Reticulon PF02453.17 KPA38676.1 - 3.4e-16 59.6 0.3 7.2e-16 58.5 0.3 1.5 1 0 0 1 1 1 1 Reticulon DUF883 PF05957.13 KPA38676.1 - 0.06 13.9 2.1 0.43 11.2 0.7 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) AI-2E_transport PF01594.16 KPA38676.1 - 0.19 10.9 2.7 0.29 10.2 0.3 2.0 2 0 0 2 2 2 0 AI-2E family transporter DivIVA PF05103.13 KPA38676.1 - 0.3 11.2 1.6 0.67 10.0 1.6 1.6 1 0 0 1 1 1 0 DivIVA protein Tannase PF07519.11 KPA38677.1 - 9.4e-97 324.8 0.2 1.2e-96 324.4 0.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KPA38677.1 - 0.025 14.1 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family UPF0565 PF10561.9 KPA38677.1 - 0.031 13.5 0.2 0.05 12.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 adh_short PF00106.25 KPA38678.1 - 1.5e-23 83.3 0.0 2.5e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA38678.1 - 1.3e-16 60.9 0.1 1.7e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPA38678.1 - 4.5e-08 32.9 0.1 5.9e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPA38678.1 - 1.1e-06 28.7 0.1 1.8e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPA38678.1 - 1.2e-06 28.5 0.1 1.6e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KPA38678.1 - 0.004 16.3 0.1 0.0057 15.8 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain CAT_RBD PF03123.15 KPA38678.1 - 0.028 14.4 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 CAT RNA binding domain SPOR PF05036.13 KPA38678.1 - 0.038 14.4 0.0 0.62 10.5 0.0 2.4 2 0 0 2 2 2 0 Sporulation related domain Glyco_transf_4 PF13439.6 KPA38678.1 - 0.047 13.7 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ApbA PF02558.16 KPA38678.1 - 0.06 13.0 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1771 PF08590.10 KPA38678.1 - 0.086 13.2 0.1 0.22 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) TFIID-18kDa PF02269.16 KPA38680.1 - 1.4e-23 82.7 0.5 3.3e-23 81.5 0.5 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 KPA38680.1 - 0.0038 17.5 0.4 0.015 15.6 0.1 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF4 PF05236.14 KPA38680.1 - 0.0051 16.6 2.2 0.0076 16.0 2.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAFII28 PF04719.14 KPA38680.1 - 0.11 12.6 0.3 0.28 11.3 0.3 1.9 1 1 0 1 1 1 0 hTAFII28-like protein conserved region tRNA_SAD PF07973.14 KPA38681.1 - 8.8e-07 28.9 1.0 2.1e-06 27.7 1.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 KPA38681.1 - 0.0067 15.0 0.0 0.01 14.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) BLUF PF04940.12 KPA38681.1 - 0.039 14.1 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Sensors of blue-light using FAD Abhydrolase_4 PF08386.10 KPA38682.1 - 1.1e-19 70.4 0.0 2e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KPA38682.1 - 7.6e-16 58.5 0.0 5e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold HET PF06985.11 KPA38683.1 - 2.5e-21 76.6 0.0 4.1e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_oxidored PF12831.7 KPA38685.1 - 4.4e-109 365.7 0.0 5.6e-109 365.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Zn_clus PF00172.18 KPA38686.1 - 8.3e-08 32.2 13.3 1.3e-07 31.6 13.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KPA38687.1 - 1e-39 136.1 0.0 1.5e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA38687.1 - 1.1e-23 84.0 0.0 1.5e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA38687.1 - 0.0026 17.7 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA38687.1 - 0.03 13.8 0.1 0.21 11.0 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2_5_RNA_ligase2 PF13563.6 KPA38688.1 - 8.5e-15 55.0 0.1 1.3e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KPA38688.1 - 0.04 14.1 0.1 0.4 10.9 0.1 2.2 2 1 0 2 2 2 0 LigT like Phosphoesterase MFS_1 PF07690.16 KPA38689.1 - 1.4e-32 113.1 35.2 4.3e-21 75.2 19.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA38689.1 - 1.9e-09 36.9 11.9 2.2e-05 23.5 1.3 2.1 2 0 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KPA38689.1 - 0.0001 21.3 6.6 0.0001 21.3 6.6 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KPA38689.1 - 0.00088 17.8 2.0 0.00088 17.8 2.0 2.8 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KPA38689.1 - 0.0098 14.2 7.4 0.19 10.0 3.7 2.7 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family ArAE_2_N PF10337.9 KPA38690.1 - 3e-65 221.1 5.5 4.2e-65 220.6 0.6 2.5 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KPA38690.1 - 2.7e-32 112.5 0.0 4.9e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KPA38690.1 - 9e-11 42.0 15.2 9e-11 42.0 15.2 2.7 3 0 0 3 3 3 1 Fusaric acid resistance protein-like DUF4795 PF16043.5 KPA38690.1 - 0.00035 20.3 1.2 0.00075 19.2 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) TetR_C_34 PF17929.1 KPA38690.1 - 1.5 9.0 3.9 29 4.8 0.1 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Mpv17_PMP22 PF04117.12 KPA38691.1 - 6.5e-14 51.9 2.6 1.2e-13 51.0 2.6 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Fungal_trans_2 PF11951.8 KPA38692.1 - 1.9e-43 148.7 0.3 2.6e-43 148.3 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA38692.1 - 6e-08 32.7 9.2 1.1e-07 31.8 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HisKA_2 PF07568.12 KPA38692.1 - 0.41 10.8 1.4 37 4.5 0.1 3.1 2 1 1 3 3 3 0 Histidine kinase Herpes_capsid PF06112.11 KPA38693.1 - 7.5 6.6 13.5 11 6.1 13.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CoA_transf_3 PF02515.17 KPA38694.1 - 1.1e-106 357.1 0.0 1.3e-106 356.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III CoA_trans PF01144.23 KPA38695.1 - 1.8e-90 302.1 1.3 1.5e-56 191.3 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase PepX_C PF08530.10 KPA38696.1 - 5.9e-34 118.0 0.0 8.5e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KPA38696.1 - 2.9e-33 115.6 0.3 9.2e-32 110.7 0.3 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Lyase_1 PF00206.20 KPA38697.1 - 1.9e-49 168.8 0.0 3.4e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KPA38697.1 - 4.1e-22 78.5 0.0 8e-21 74.4 0.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 KPA38697.1 - 0.038 14.1 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal HAUS2 PF15003.6 KPA38697.1 - 0.1 12.3 0.1 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 Fe-ADH PF00465.19 KPA38698.1 - 1.1e-56 192.3 0.0 1.4e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KPA38698.1 - 1.3e-06 28.3 0.3 0.008 15.9 0.1 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Thiolase_N PF00108.23 KPA38699.1 - 1.6e-74 250.6 0.4 2.2e-74 250.1 0.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPA38699.1 - 2.2e-38 130.7 0.1 6.3e-38 129.2 0.0 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KPA38699.1 - 1.2e-06 28.3 0.5 3.4e-06 26.8 0.4 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KPA38699.1 - 0.085 12.7 0.3 6.1 6.8 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HgmA PF04209.13 KPA38700.1 - 1.2e-135 452.6 0.1 1.3e-135 452.4 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Fungal_trans PF04082.18 KPA38701.1 - 5e-06 25.7 0.3 4.6e-05 22.6 0.1 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain COesterase PF00135.28 KPA38702.1 - 6.2e-47 160.6 0.2 8.3e-35 120.6 0.2 3.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA38702.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.22 KPA38703.1 - 1.5e-59 202.0 0.0 9.6e-59 199.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KPA38704.1 - 6.7e-61 205.7 0.0 1.2e-60 204.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KPA38704.1 - 3.5e-31 108.3 0.4 5.4e-31 107.7 0.4 1.3 1 0 0 1 1 1 1 Flavodoxin RabGAP-TBC PF00566.18 KPA38705.1 - 5.6e-35 120.9 0.0 4.9e-17 62.3 0.0 3.4 3 0 0 3 3 3 3 Rab-GTPase-TBC domain UQ_con PF00179.26 KPA38706.1 - 2.2e-39 134.3 0.0 2.5e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPA38706.1 - 0.0002 21.1 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B PEP-utilisers_N PF05524.13 KPA38706.1 - 0.015 15.5 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal RWD PF05773.22 KPA38706.1 - 0.033 14.5 0.0 0.046 14.0 0.0 1.3 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 KPA38706.1 - 0.058 13.3 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.25 KPA38707.1 - 0.00033 20.1 0.0 0.00043 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain ChAPs PF09295.10 KPA38708.1 - 2.2e-151 504.4 0.0 2.8e-151 504.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KPA38708.1 - 8.9e-06 26.1 1.2 1.2 10.1 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPA38708.1 - 1.1e-05 25.2 0.1 0.0046 17.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPA38708.1 - 3.6e-05 23.5 0.7 0.26 11.4 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPA38708.1 - 0.00012 22.0 0.6 0.11 12.7 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KPA38708.1 - 0.00091 19.0 0.1 1.2 9.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KPA38708.1 - 0.0025 17.9 0.1 0.41 10.8 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPA38708.1 - 0.0097 16.2 0.1 3.6 7.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KPA38708.1 - 0.023 15.3 0.3 21 6.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KPA38708.1 - 0.037 14.5 0.0 1.4 9.5 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 KPA38708.1 - 0.049 12.9 2.5 0.069 12.3 0.5 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA38708.1 - 0.11 12.8 2.0 15 5.9 0.0 3.9 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DEAD PF00270.29 KPA38711.1 - 7.4e-46 156.1 0.0 1.1e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA38711.1 - 8.4e-32 109.8 0.2 5.3e-31 107.2 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA38711.1 - 1.6e-05 25.0 0.0 3.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Terminase_6 PF03237.15 KPA38711.1 - 0.16 11.6 0.0 0.49 10.0 0.0 1.8 2 0 0 2 2 2 0 Terminase-like family Brix PF04427.18 KPA38712.1 - 4.1e-50 170.6 0.0 5.4e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain AAA_11 PF13086.6 KPA38712.1 - 0.86 9.3 5.8 1.1 9.0 4.2 1.9 2 0 0 2 2 2 0 AAA domain PP2C PF00481.21 KPA38713.1 - 1.7e-30 106.6 0.0 2.7e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C 2-Hacid_dh_C PF02826.19 KPA38714.1 - 4e-56 189.2 0.0 5.9e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPA38714.1 - 7.6e-15 54.8 0.0 9.6e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KPA38714.1 - 1.4e-08 35.1 0.4 3.1e-08 33.9 0.2 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KPA38714.1 - 0.0054 16.3 0.0 0.0093 15.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KPA38714.1 - 0.013 16.0 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KPA38714.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_11 PF08241.12 KPA38716.1 - 2.1e-14 53.9 0.0 4.8e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA38716.1 - 8.6e-14 52.0 0.0 2e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA38716.1 - 1.1e-11 44.5 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KPA38716.1 - 1.5e-09 37.9 0.0 2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA38716.1 - 1.9e-08 34.9 0.0 3.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA38716.1 - 1.7e-06 28.0 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Arc_C PF18162.1 KPA38716.1 - 0.04 13.8 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Arc C-lobe Nucleoporin_N PF08801.11 KPA38717.1 - 2.8e-97 326.2 0.1 4.3e-97 325.6 0.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KPA38717.1 - 1.4e-51 176.0 2.1 1.3e-50 172.8 2.0 2.0 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Saw1 PF11561.8 KPA38717.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Single strand annealing-weakened 1 adh_short PF00106.25 KPA38718.1 - 5.1e-39 133.8 0.0 6.6e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA38718.1 - 2.5e-24 86.1 0.0 3.3e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA38718.1 - 2.9e-07 30.6 0.0 8.4e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA38718.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Erg28 PF03694.13 KPA38719.1 - 2.8e-43 146.8 0.7 3.4e-43 146.5 0.7 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.22 KPA38720.1 - 1.6e-70 237.3 0.2 6e-70 235.4 0.4 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KPA38720.1 - 2.3e-58 196.6 0.1 6e-58 195.3 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KPA38720.1 - 3.2e-06 27.8 0.0 2.7e-05 24.8 0.0 2.4 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KPA38720.1 - 0.01 16.3 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding WG_beta_rep PF14903.6 KPA38720.1 - 0.18 12.1 0.1 0.43 10.9 0.1 1.7 1 0 0 1 1 1 0 WG containing repeat ZZ PF00569.17 KPA38721.1 - 7.1e-09 35.3 4.8 1.2e-08 34.6 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KPA38721.1 - 7.8e-09 35.6 0.5 2.7e-08 33.9 0.0 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain SWIRM PF04433.17 KPA38721.1 - 7.5e-08 32.6 0.0 2.6e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Imm17 PF15562.6 KPA38722.1 - 0.0069 16.2 0.6 0.011 15.6 0.5 1.4 1 1 0 1 1 1 1 Immunity protein 17 Gram_pos_anchor PF00746.21 KPA38723.1 - 0.05 13.5 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Rhodanese PF00581.20 KPA38724.1 - 3.9e-13 49.9 0.0 4.7e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain HD_3 PF13023.6 KPA38725.1 - 8.9e-50 168.8 0.0 1.2e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KPA38725.1 - 6.6e-11 42.3 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Polysacc_deac_1 PF01522.21 KPA38727.1 - 2.9e-33 114.4 0.0 6.5e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KPA38727.1 - 4.4e-05 22.8 0.2 0.00044 19.5 0.0 2.1 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 adh_short PF00106.25 KPA38728.1 - 6.8e-12 45.3 0.0 6.1e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA38728.1 - 4.7e-06 26.3 0.0 0.00024 20.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Pkinase PF00069.25 KPA38730.1 - 5.9e-19 68.5 0.0 1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KPA38730.1 - 1.7e-08 33.6 0.2 5.4e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KPA38730.1 - 1.9e-08 33.9 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 KPA38730.1 - 0.034 13.8 0.1 0.077 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 WaaY PF06176.11 KPA38730.1 - 0.037 13.6 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Anillin_N PF16018.5 KPA38730.1 - 0.078 13.6 0.1 0.28 11.8 0.1 1.9 1 0 0 1 1 1 0 Anillin N-terminus Lactonase PF10282.9 KPA38732.1 - 1.3e-54 185.8 0.0 1.7e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 KPA38732.1 - 0.002 16.8 0.0 0.48 8.9 0.0 2.9 2 1 1 3 3 3 2 Cytochrome D1 heme domain WD40 PF00400.32 KPA38732.1 - 0.078 13.9 0.2 4.3 8.4 0.1 3.3 2 0 0 2 2 2 0 WD domain, G-beta repeat Peptidase_C2 PF00648.21 KPA38733.1 - 6.7e-60 202.6 0.4 2.9e-59 200.5 0.4 1.8 1 1 0 1 1 1 1 Calpain family cysteine protease PEARLI-4 PF05278.12 KPA38733.1 - 0.027 14.1 1.0 0.027 14.1 1.0 1.8 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Antimicrobial17 PF08129.11 KPA38733.1 - 0.081 12.9 0.0 3.1 7.8 0.0 2.6 3 0 0 3 3 3 0 Alpha/beta enterocin family DUF5082 PF16888.5 KPA38733.1 - 0.17 12.1 3.5 0.98 9.7 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 KPA38733.1 - 0.18 11.1 2.0 0.29 10.4 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_HK97_TLTM PF06120.11 KPA38733.1 - 0.3 10.3 1.8 0.47 9.6 1.8 1.3 1 0 0 1 1 1 0 Tail length tape measure protein ATG16 PF08614.11 KPA38733.1 - 0.3 11.3 4.1 2.9 8.1 4.1 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KPA38733.1 - 3.7 6.3 8.5 20 4.0 8.5 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Fungal_trans PF04082.18 KPA38734.1 - 1.1e-06 28.0 0.4 1.5e-06 27.5 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Chromo PF00385.24 KPA38735.1 - 1.1e-13 50.9 1.6 1.2e-09 37.9 0.5 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-binding PF00249.31 KPA38735.1 - 0.018 15.2 0.0 0.05 13.8 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Tudor-knot PF11717.8 KPA38735.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF4064 PF13273.6 KPA38737.1 - 0.089 13.1 0.9 0.24 11.7 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) MASE4 PF17158.4 KPA38737.1 - 0.15 11.3 5.8 0.25 10.6 5.8 1.3 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain HET PF06985.11 KPA38738.1 - 8e-25 87.9 0.0 2.1e-24 86.6 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KPA38739.1 - 1.1e-11 44.3 43.7 1.2e-11 44.1 40.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.20 KPA38740.1 - 1.6e-25 90.1 0.1 3.3e-24 85.9 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPA38740.1 - 5.9e-17 62.3 0.1 1e-11 45.0 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Fe-ADH PF00465.19 KPA38741.1 - 4.7e-52 177.0 0.0 5.4e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KPA38741.1 - 6.8e-12 45.6 0.5 0.00016 21.4 0.0 2.7 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase MFS_1 PF07690.16 KPA38742.1 - 9.3e-35 120.2 45.1 3.3e-34 118.4 45.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3425 PF11905.8 KPA38742.1 - 3e-12 46.6 1.3 7e-12 45.4 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) TRI12 PF06609.13 KPA38742.1 - 0.0013 17.3 19.5 0.0073 14.8 19.5 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PetG PF02529.15 KPA38742.1 - 0.17 11.8 1.8 11 6.0 0.1 2.7 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 Peptidase_M48_N PF16491.5 KPA38742.1 - 0.4 10.6 5.1 0.14 12.0 0.2 2.6 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices YtpI PF14007.6 KPA38742.1 - 1.1 9.4 7.0 2 8.6 1.5 3.2 3 0 0 3 3 3 0 YtpI-like protein p450 PF00067.22 KPA38743.1 - 8.1e-42 143.5 0.2 4.6e-27 94.9 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 DHR10 PF18595.1 KPA38744.1 - 0.01 15.9 13.9 0.01 15.9 13.9 5.1 4 1 1 5 5 5 0 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 KPA38744.1 - 5.1 7.1 35.9 0.51 10.4 11.6 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Glyco_hydro_3_C PF01915.22 KPA38745.1 - 1.8e-43 148.9 0.0 5.9e-43 147.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPA38745.1 - 1.8e-39 136.0 0.0 3.2e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPA38745.1 - 5.9e-24 84.0 0.2 1.1e-23 83.1 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Zn_clus PF00172.18 KPA38746.1 - 2.9e-07 30.5 10.9 5.4e-07 29.6 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF630 PF04783.12 KPA38746.1 - 7.9 6.7 7.6 15 5.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF630) FAD_binding_3 PF01494.19 KPA38747.1 - 6.7e-23 81.5 0.0 2.3e-22 79.7 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KPA38747.1 - 0.00016 20.8 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.27 KPA38747.1 - 0.00049 20.6 0.1 0.0017 18.9 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA38747.1 - 0.00093 19.4 0.1 0.002 18.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA38747.1 - 0.027 13.7 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4264 PF14084.6 KPA38747.1 - 0.16 11.7 1.6 15 5.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) Lycopene_cycl PF05834.12 KPA38747.1 - 0.22 10.5 0.1 0.55 9.2 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAM209 PF15206.6 KPA38748.1 - 0.2 11.4 0.7 0.5 10.2 0.7 1.7 1 0 0 1 1 1 0 FAM209 family ORC6 PF05460.13 KPA38748.1 - 4.3 6.5 15.7 0.48 9.7 9.6 2.0 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Fungal_trans_2 PF11951.8 KPA38749.1 - 3.1e-32 111.8 0.2 4e-32 111.5 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA38749.1 - 1.1e-10 41.4 8.9 1.1e-10 41.4 8.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 KPA38749.1 - 0.43 10.4 7.8 0.13 12.0 1.4 2.6 2 0 0 2 2 2 0 Integrin plexin domain ADH_zinc_N_2 PF13602.6 KPA38750.1 - 2.4e-19 70.7 0.3 1.6e-18 68.0 0.3 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KPA38750.1 - 2.1e-12 47.2 0.0 8.4e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA38750.1 - 6.4e-05 22.8 0.9 0.002 18.0 0.0 2.9 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Isochorismatase PF00857.20 KPA38751.1 - 1.1e-15 58.3 0.0 1.9e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Phage_holin_4_2 PF04020.13 KPA38753.1 - 1.1 10.0 12.9 1.4 9.7 0.2 3.1 3 0 0 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV Glyco_hydro_43 PF04616.14 KPA38754.1 - 3.8e-39 134.7 3.2 5.1e-39 134.3 3.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KPA38754.1 - 1.3e-23 83.8 0.5 4.1e-23 82.2 0.3 1.8 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain Porin_3 PF01459.22 KPA38754.1 - 0.036 13.5 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic porin Glyco_hydro_43 PF04616.14 KPA38755.1 - 8.4e-54 182.8 3.4 8.4e-54 182.8 3.4 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KPA38755.1 - 4.2e-41 140.2 0.9 9.5e-41 139.0 0.9 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 KPA38755.1 - 6e-09 36.0 0.3 1.3e-08 35.0 0.3 1.6 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 KPA38755.1 - 1.6e-05 24.6 1.3 3.3e-05 23.6 1.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Hexokinase_2 PF03727.16 KPA38756.1 - 1.2e-62 211.5 0.1 7.1e-61 205.7 0.1 2.2 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KPA38756.1 - 7.7e-62 208.7 0.0 1.3e-61 208.0 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Glucosamine_iso PF01182.20 KPA38758.1 - 1.8e-19 70.5 0.0 2.8e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.13 KPA38758.1 - 0.072 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Sugar_tr PF00083.24 KPA38760.1 - 6.3e-69 233.0 18.6 7.5e-69 232.7 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38760.1 - 3.2e-26 92.1 23.8 4.7e-26 91.5 23.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_2_N PF02837.18 KPA38761.1 - 6.9e-45 153.0 0.8 5.1e-44 150.2 0.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KPA38761.1 - 4.9e-07 30.4 0.2 1.2e-06 29.1 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KPA38761.1 - 0.00022 21.7 0.1 0.00064 20.3 0.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Cupin_5 PF06172.11 KPA38761.1 - 0.058 13.6 0.0 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily (DUF985) ABC_tran PF00005.27 KPA38766.1 - 4.2e-06 27.3 0.0 1.4e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KPA38766.1 - 5.3e-05 22.8 0.0 7.4e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF4019 PF13211.6 KPA38767.1 - 0.047 14.1 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) ATP-synt_F PF01990.17 KPA38767.1 - 0.14 12.5 0.8 0.54 10.6 0.1 2.1 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit NAD_binding_6 PF08030.12 KPA38768.1 - 0.00059 20.0 0.1 0.0015 18.7 0.1 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain JIP_LZII PF16471.5 KPA38768.1 - 0.35 11.1 6.9 0.092 12.9 3.2 1.9 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF2070 PF09843.9 KPA38768.1 - 1 7.6 7.8 1.4 7.1 7.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_C48 PF02902.19 KPA38771.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain L27_1 PF09058.10 KPA38772.1 - 0.099 12.6 0.2 0.28 11.2 0.2 1.8 1 1 0 1 1 1 0 L27_1 Phage_int_SAM_2 PF12834.7 KPA38772.1 - 0.14 12.8 0.0 0.24 12.1 0.0 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal NACHT PF05729.12 KPA38773.1 - 4.9e-11 42.8 0.1 1.5e-10 41.3 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPA38773.1 - 1.8e-08 34.9 0.0 9.6e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPA38773.1 - 2.9e-08 34.1 0.1 2.5e-07 31.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Ank_2 PF12796.7 KPA38773.1 - 6.6e-07 29.8 0.1 3e-05 24.5 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA38773.1 - 1.1e-05 25.9 0.2 0.00055 20.5 0.1 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF87 PF01935.17 KPA38773.1 - 0.00025 21.2 0.0 0.0011 19.1 0.0 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain Ank_3 PF13606.6 KPA38773.1 - 0.00031 21.0 0.2 11 7.0 0.0 5.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KPA38773.1 - 0.00035 20.8 0.4 0.16 12.3 0.0 3.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) KAP_NTPase PF07693.14 KPA38773.1 - 0.0032 16.8 0.0 0.02 14.1 0.0 2.1 1 1 0 2 2 2 1 KAP family P-loop domain RAP1 PF07218.11 KPA38773.1 - 0.05 11.9 1.9 0.078 11.3 1.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ABC_tran PF00005.27 KPA38773.1 - 0.074 13.6 0.0 0.65 10.5 0.0 2.6 2 0 0 2 2 2 0 ABC transporter DUF4795 PF16043.5 KPA38774.1 - 0.012 15.2 14.7 0.028 14.0 14.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) TMF_TATA_bd PF12325.8 KPA38774.1 - 0.019 15.2 11.8 0.092 13.0 8.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 KPA38774.1 - 0.15 12.4 5.2 3.5 8.0 1.8 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1178 PF06676.11 KPA38774.1 - 0.73 10.2 9.6 5 7.5 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) MCU PF04678.13 KPA38774.1 - 4.4 7.4 11.7 1.2 9.2 7.1 1.9 1 1 1 2 2 2 0 Mitochondrial calcium uniporter LPP PF04728.13 KPA38774.1 - 5.8 7.4 9.7 1.7 9.1 5.7 2.2 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Cupin_2 PF07883.11 KPA38775.1 - 6.1e-10 38.7 0.0 0.0014 18.3 0.0 2.6 2 1 0 2 2 2 2 Cupin domain Ppnp PF06865.11 KPA38775.1 - 0.00048 20.5 0.0 0.001 19.4 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase AraC_binding PF02311.19 KPA38775.1 - 0.0034 17.3 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 AraC-like ligand binding domain CoA_transf_3 PF02515.17 KPA38776.1 - 9.4e-126 419.8 0.0 1.1e-125 419.6 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III CoA_trans PF01144.23 KPA38777.1 - 1.1e-81 273.4 4.1 1.9e-56 190.9 0.2 2.3 2 0 0 2 2 2 2 Coenzyme A transferase PepX_C PF08530.10 KPA38777.1 - 1.6e-33 116.5 0.0 2.5e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KPA38777.1 - 5.5e-33 114.7 0.2 4e-31 108.6 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) CN_hydrolase PF00795.22 KPA38777.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase Lyase_1 PF00206.20 KPA38778.1 - 1.1e-47 162.9 0.0 2.1e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KPA38778.1 - 5.8e-22 78.0 0.0 1.2e-20 73.8 0.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus FumaraseC_C PF10415.9 KPA38778.1 - 0.051 14.0 0.0 0.97 9.9 0.0 2.8 2 0 0 2 2 2 0 Fumarase C C-terminus Fe-ADH PF00465.19 KPA38779.1 - 5.3e-56 190.0 0.0 7.1e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KPA38779.1 - 1.2e-06 28.4 0.2 0.015 15.0 0.1 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Thiolase_N PF00108.23 KPA38780.1 - 2.7e-75 253.1 1.4 1.7e-74 250.5 0.5 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPA38780.1 - 6.6e-44 148.5 0.3 1.7e-43 147.2 0.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KPA38780.1 - 8.7e-07 28.8 0.3 3.8e-06 26.7 0.4 2.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KPA38780.1 - 0.078 12.8 0.2 5.4 6.9 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Mito_carr PF00153.27 KPA38781.1 - 2.2e-39 133.3 0.7 1.6e-19 69.6 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein HgmA PF04209.13 KPA38782.1 - 6.1e-136 453.5 0.1 7.2e-136 453.3 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Fungal_trans PF04082.18 KPA38783.1 - 5.2e-07 29.0 0.8 2.1e-06 26.9 0.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain SUIM_assoc PF16619.5 KPA38783.1 - 0.011 15.7 2.1 0.028 14.5 2.1 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SPAN PF02510.14 KPA38783.1 - 0.83 8.8 2.6 1.5 8.0 2.6 1.3 1 0 0 1 1 1 0 Surface presentation of antigens protein COesterase PF00135.28 KPA38784.1 - 7.5e-43 147.2 0.0 3.2e-33 115.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA38784.1 - 8.4e-06 25.8 0.0 1.5e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.22 KPA38785.1 - 3.5e-60 204.1 0.0 3.1e-59 200.9 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KPA38786.1 - 5.6e-61 205.9 0.0 9.6e-61 205.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KPA38786.1 - 5.6e-32 110.9 0.3 8.3e-32 110.4 0.3 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KPA38786.1 - 1e-09 39.0 0.0 5.8e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain GCV_T PF01571.21 KPA38787.1 - 2.2e-62 210.7 0.0 3.9e-62 209.9 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KPA38787.1 - 2.5e-43 149.0 0.2 4.4e-43 148.2 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 KPA38787.1 - 1.9e-22 79.0 0.1 4.3e-22 77.8 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 KPA38787.1 - 8.7e-18 64.4 0.0 1.7e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox PF00070.27 KPA38787.1 - 6.2e-06 26.7 0.2 0.029 14.9 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA38787.1 - 7.3e-06 25.4 0.1 0.076 12.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA38787.1 - 0.00033 20.0 0.1 0.12 11.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPA38787.1 - 0.0012 17.8 0.6 0.012 14.5 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KPA38787.1 - 0.0015 17.7 0.1 0.0026 16.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KPA38787.1 - 0.0032 17.5 0.7 0.77 9.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KPA38787.1 - 0.01 15.1 0.4 2.7 7.1 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KPA38787.1 - 0.015 15.6 0.0 0.046 13.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KPA38787.1 - 0.023 14.8 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KPA38787.1 - 0.029 14.6 0.1 0.092 13.0 0.0 1.9 2 0 0 2 2 1 0 TrkA-N domain Amino_oxidase PF01593.24 KPA38787.1 - 0.038 13.3 0.0 0.082 12.2 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KPA38787.1 - 0.086 11.9 0.5 8.9 5.2 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.21 KPA38787.1 - 0.1 11.9 0.0 0.45 9.8 0.0 1.9 2 0 0 2 2 2 0 ThiF family ADH_zinc_N PF00107.26 KPA38788.1 - 1.1e-12 48.1 0.0 1.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA38788.1 - 4.8e-07 30.9 0.0 1e-06 29.8 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA38788.1 - 0.00063 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KPA38788.1 - 0.032 14.1 0.0 0.094 12.6 0.0 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase baeRF_family7 PF18849.1 KPA38788.1 - 0.066 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 AA_permease PF00324.21 KPA38789.1 - 8.5e-142 473.1 41.3 9.7e-142 472.9 41.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA38789.1 - 1.4e-41 142.7 46.6 1.9e-41 142.3 46.6 1.2 1 0 0 1 1 1 1 Amino acid permease Methyltransf_31 PF13847.6 KPA38790.1 - 0.053 13.3 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_3 PF00933.21 KPA38791.1 - 1.4e-53 182.3 0.0 2.7e-53 181.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KPA38791.1 - 2.7e-52 177.7 0.0 5e-52 176.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KPA38791.1 - 2.2e-20 72.5 0.1 4.3e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KPA38791.1 - 1.2e-06 28.4 0.1 2.4e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 PA14 domain adh_short_C2 PF13561.6 KPA38793.1 - 4.3e-50 170.5 0.0 5e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA38793.1 - 6.1e-41 140.0 0.0 7.7e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA38793.1 - 1.2e-08 35.0 0.1 1.9e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KPA38793.1 - 0.092 12.1 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aldo_ket_red PF00248.21 KPA38794.1 - 2.6e-50 171.3 0.0 3e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PGM_PMM_I PF02878.16 KPA38794.1 - 0.076 12.7 0.1 0.49 10.1 0.1 1.9 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Pectinesterase PF01095.19 KPA38795.1 - 6.8e-45 153.0 9.0 9.9e-45 152.5 9.0 1.2 1 0 0 1 1 1 1 Pectinesterase AA_permease PF00324.21 KPA38796.1 - 1.6e-125 419.4 40.5 2.5e-125 418.8 40.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA38796.1 - 3.7e-38 131.5 45.2 1.7e-36 126.0 44.0 2.2 2 0 0 2 2 2 2 Amino acid permease Vps62 PF06101.11 KPA38796.1 - 1.1e-11 43.8 1.4 1.1e-10 40.5 0.9 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 ABC_tran PF00005.27 KPA38797.1 - 2.3e-48 164.2 0.1 1.8e-26 93.3 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KPA38797.1 - 7.9e-15 55.4 4.8 0.00029 20.7 0.8 4.6 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPA38797.1 - 1.3e-12 47.6 0.1 0.00018 21.0 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPA38797.1 - 4.2e-10 40.5 0.3 2.4e-05 25.0 0.0 2.6 3 0 0 3 3 2 2 AAA domain Chromo PF00385.24 KPA38797.1 - 2.9e-09 36.7 0.0 6.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 KPA38797.1 - 2.1e-07 31.0 0.0 0.0035 17.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA38797.1 - 3.6e-07 30.2 0.1 0.0026 17.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KPA38797.1 - 5.5e-07 29.2 0.7 0.0071 16.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KPA38797.1 - 1.5e-05 25.3 0.0 0.0014 18.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPA38797.1 - 4e-05 23.9 0.1 0.62 10.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KPA38797.1 - 0.00011 22.7 0.0 0.063 13.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KPA38797.1 - 0.00021 21.1 0.1 0.22 11.2 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 KPA38797.1 - 0.0014 18.7 0.9 0.43 10.6 0.1 3.2 3 0 0 3 3 2 1 Helicase HerA, central domain NACHT PF05729.12 KPA38797.1 - 0.0022 18.0 0.1 1.2 9.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 KPA38797.1 - 0.0023 18.3 0.1 4 7.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.6 KPA38797.1 - 0.0024 18.1 0.0 1.5 9.2 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KPA38797.1 - 0.003 17.7 1.1 2.5 8.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KPA38797.1 - 0.0044 16.7 0.1 2.8 7.6 0.1 3.2 3 0 0 3 3 2 1 AAA domain AAA_13 PF13166.6 KPA38797.1 - 0.0062 15.2 0.0 1.3 7.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KPA38797.1 - 0.0077 16.0 0.5 0.55 9.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KPA38797.1 - 0.0081 15.2 0.2 2.3 7.2 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KPA38797.1 - 0.0095 16.4 0.0 5.8 7.4 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPA38797.1 - 0.014 15.8 0.0 2.2 8.7 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain PduV-EutP PF10662.9 KPA38797.1 - 0.015 15.0 0.0 0.84 9.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_27 PF13514.6 KPA38797.1 - 0.017 14.7 0.8 7.5 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KPA38797.1 - 0.022 14.8 0.0 0.41 10.7 0.0 2.6 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 KPA38797.1 - 0.032 14.5 0.0 5.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KPA38797.1 - 0.045 12.9 0.1 2.8 7.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 KPA38797.1 - 0.05 13.7 0.0 6.5 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KPA38797.1 - 0.055 12.6 0.0 3.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SR-25 PF10500.9 KPA38797.1 - 0.092 12.3 3.3 0.17 11.5 3.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TsaE PF02367.17 KPA38797.1 - 0.11 12.5 0.3 19 5.3 0.1 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3584 PF12128.8 KPA38797.1 - 0.11 9.9 2.9 3.4 5.1 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Septin PF00735.18 KPA38797.1 - 0.14 11.4 0.0 13 5.0 0.0 2.3 2 0 0 2 2 2 0 Septin LMSTEN PF07988.12 KPA38797.1 - 0.14 11.6 0.3 0.43 10.1 0.3 1.8 1 0 0 1 1 1 0 LMSTEN motif NTPase_1 PF03266.15 KPA38797.1 - 0.15 12.0 0.4 19 5.1 0.3 2.8 2 0 0 2 2 2 0 NTPase cobW PF02492.19 KPA38797.1 - 1.3 8.6 3.3 25 4.4 0.1 2.9 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_trans_2_3 PF13632.6 KPA38798.1 - 1.3e-50 172.1 4.6 2.5e-50 171.2 4.5 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KPA38798.1 - 6.8e-05 22.7 0.0 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KPA38798.1 - 0.029 13.8 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 KPA38799.1 - 7.4e-16 58.1 1.2 1.3e-15 57.3 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fasciclin PF02469.22 KPA38800.1 - 2.3e-39 134.5 0.0 6.9e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Orn_Arg_deC_N PF02784.16 KPA38800.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain NAT PF04768.13 KPA38802.1 - 5.8e-45 153.0 0.0 1.1e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KPA38802.1 - 3e-32 112.1 0.3 5.8e-32 111.2 0.0 1.6 2 0 0 2 2 2 1 Amino acid kinase family DUF1338 PF07063.13 KPA38802.1 - 0.082 12.1 0.0 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1338) Synaptobrevin PF00957.21 KPA38803.1 - 4.5e-33 112.9 1.2 5.2e-33 112.7 1.2 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 KPA38803.1 - 0.089 13.5 0.1 0.28 11.9 0.1 1.7 1 1 1 2 2 2 0 AT-hook-containing transcription factor MCU PF04678.13 KPA38803.1 - 0.15 12.1 0.0 0.18 11.9 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF515 PF04415.12 KPA38803.1 - 1.4 7.3 3.8 1.5 7.2 3.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF515) Zn_clus PF00172.18 KPA38804.1 - 1.5e-09 37.8 12.1 2.9e-09 36.9 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cerato-platanin PF07249.12 KPA38806.1 - 8.2e-06 25.9 0.1 1.5e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Cerato-platanin FAD_binding_4 PF01565.23 KPA38807.1 - 9.6e-22 77.2 0.5 4.7e-21 75.0 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KPA38807.1 - 5.6e-11 42.4 0.1 1.2e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like SGL PF08450.12 KPA38808.1 - 2.9e-06 27.1 0.1 4.3e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KPA38808.1 - 0.038 14.0 2.8 6.7 6.9 0.0 4.0 4 0 0 4 4 4 0 NHL repeat CooT PF10133.9 KPA38809.1 - 0.00023 21.4 0.0 0.00049 20.3 0.0 1.5 1 0 0 1 1 1 1 CO dehydrogenase accessory protein CooT MMR_HSR1 PF01926.23 KPA38809.1 - 0.0064 16.6 0.0 0.029 14.5 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Host_attach PF10116.9 KPA38809.1 - 0.17 12.4 1.3 0.42 11.2 1.3 1.7 1 0 0 1 1 1 0 Protein required for attachment to host cells Asp PF00026.23 KPA38810.1 - 1.4e-52 179.1 0.1 2.6e-52 178.2 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA38810.1 - 1.7e-05 25.1 0.0 1.7e-05 25.1 0.0 3.0 2 2 1 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KPA38810.1 - 0.026 14.3 0.0 0.73 9.6 0.0 2.6 1 1 0 2 2 2 0 Xylanase inhibitor C-terminal NESP55 PF06390.12 KPA38810.1 - 0.17 11.5 10.5 0.31 10.6 10.5 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF5582 PF17819.1 KPA38810.1 - 3.8 8.0 6.1 7.2 7.1 6.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5582) CwfJ_C_1 PF04677.15 KPA38811.1 - 4.9e-27 94.2 0.0 8e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KPA38811.1 - 3.1e-25 88.9 0.0 3.1e-25 88.9 0.0 2.4 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 FumaraseC_C PF10415.9 KPA38811.1 - 0.097 13.1 0.2 2.3 8.7 0.1 2.8 2 0 0 2 2 2 0 Fumarase C C-terminus Abhydrolase_1 PF00561.20 KPA38812.1 - 3.2e-09 36.8 0.0 1.1e-08 35.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA38812.1 - 1.2e-05 24.7 0.0 0.0011 18.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Wound_ind PF08186.11 KPA38812.1 - 0.74 10.3 5.8 26 5.3 0.2 4.1 3 0 0 3 3 3 0 Wound-inducible basic protein family FA_hydroxylase PF04116.13 KPA38813.1 - 2.6e-14 53.7 2.5 2.6e-14 53.7 2.5 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily ICE2 PF08426.10 KPA38813.1 - 0.053 12.6 2.2 0.085 12.0 2.2 1.4 1 0 0 1 1 1 0 ICE2 TMEM251 PF15190.6 KPA38813.1 - 0.13 12.2 0.2 0.13 12.2 0.2 1.9 2 1 0 2 2 2 0 Transmembrane protein 251 DUF3808 PF10300.9 KPA38814.1 - 1.7e-123 412.9 0.0 2.1e-123 412.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 KPA38814.1 - 0.043 14.3 0.1 4.2 8.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank PF00023.30 KPA38815.1 - 2.3e-27 94.2 5.1 9.7e-07 29.0 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KPA38815.1 - 9.3e-27 93.1 5.8 8.6e-07 29.4 0.0 5.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA38815.1 - 1.5e-24 86.4 1.9 3.5e-12 46.7 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA38815.1 - 1e-23 83.0 4.6 1.3e-07 31.8 0.0 4.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA38815.1 - 2.8e-21 73.3 1.8 0.00067 19.9 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat DHBP_synthase PF00926.19 KPA38815.1 - 0.097 12.2 0.0 9.6 5.7 0.0 2.1 2 0 0 2 2 2 0 3,4-dihydroxy-2-butanone 4-phosphate synthase NmrA PF05368.13 KPA38816.1 - 3.2e-32 112.0 0.0 1e-31 110.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA38816.1 - 2e-10 40.9 0.0 2.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA38816.1 - 0.00037 20.1 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA38816.1 - 0.0052 15.8 0.0 0.0073 15.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KPA38816.1 - 0.022 15.0 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 KPA38816.1 - 0.065 12.7 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase MatE PF01554.18 KPA38817.1 - 1.8e-49 167.5 28.8 3.9e-32 111.1 11.8 2.2 2 0 0 2 2 2 2 MatE DUF5389 PF17364.2 KPA38817.1 - 0.00032 20.7 0.1 0.0013 18.7 0.1 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5389) Sec2p PF06428.11 KPA38818.1 - 1.8e-27 95.1 18.3 1.8e-27 95.1 18.3 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p KfrA_N PF11740.8 KPA38818.1 - 0.022 15.5 15.3 1.1 9.9 10.5 2.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Spc29 PF17082.5 KPA38818.1 - 0.12 12.2 7.2 0.25 11.2 7.2 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Pox_A_type_inc PF04508.12 KPA38818.1 - 0.13 12.2 1.1 0.26 11.2 0.1 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2310 PF10071.9 KPA38818.1 - 0.15 11.3 0.6 0.25 10.6 0.6 1.2 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Filament PF00038.21 KPA38818.1 - 0.15 11.6 19.6 0.23 11.0 19.0 1.5 1 1 0 1 1 1 0 Intermediate filament protein DUF5401 PF17380.2 KPA38818.1 - 0.74 7.8 13.4 1.1 7.3 13.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) MCPVI PF02993.14 KPA38818.1 - 0.97 9.2 5.3 0.52 10.1 2.3 2.2 2 1 0 2 2 2 0 Minor capsid protein VI Tropomyosin_1 PF12718.7 KPA38818.1 - 4.2 7.5 24.1 0.97 9.6 19.7 2.0 1 1 1 2 2 2 0 Tropomyosin like zf-C2H2_4 PF13894.6 KPA38818.1 - 4.5 8.4 5.2 2 9.5 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger HALZ PF02183.18 KPA38818.1 - 8.8 6.6 7.8 1.6 9.0 1.3 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper PMT PF02366.18 KPA38819.1 - 7.4e-81 271.3 17.8 1.7e-80 270.2 17.8 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KPA38819.1 - 1.9e-67 226.7 12.3 1.9e-67 226.7 12.3 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KPA38819.1 - 1.1e-47 162.3 0.1 4.9e-46 156.9 0.0 2.4 2 0 0 2 2 2 1 MIR domain TPR_2 PF07719.17 KPA38820.1 - 1.9e-05 24.4 2.9 0.2 11.9 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KPA38820.1 - 5.8e-05 23.3 5.1 0.079 13.3 0.1 4.4 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KPA38820.1 - 9.8e-05 22.9 7.2 3.6 8.7 0.0 6.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPA38820.1 - 0.00012 22.5 5.4 0.025 15.1 0.1 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KPA38820.1 - 0.0012 19.3 2.5 43 5.0 0.0 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KPA38820.1 - 0.0016 18.2 1.1 1.1 9.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KPA38820.1 - 0.0043 17.5 9.9 0.32 11.8 0.3 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA38820.1 - 0.018 15.2 0.3 21 5.4 0.2 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KPA38820.1 - 0.032 14.3 0.1 21 5.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPA38820.1 - 0.064 13.1 0.1 13 5.8 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PRP21_like_P PF12230.8 KPA38821.1 - 2.8e-54 184.3 14.3 8.6e-54 182.7 14.3 1.8 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KPA38821.1 - 1.4e-40 137.0 1.4 7.7e-21 73.8 0.1 2.6 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 KPA38821.1 - 0.02 14.5 0.3 0.037 13.6 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Orbi_VP6 PF01516.16 KPA38821.1 - 0.031 13.8 1.0 0.087 12.3 1.0 1.7 1 0 0 1 1 1 0 Orbivirus helicase VP6 DRY_EERY PF09750.9 KPA38821.1 - 1.7 8.9 9.3 8.6 6.6 2.2 2.5 2 0 0 2 2 2 0 Alternative splicing regulator PX PF00787.24 KPA38822.1 - 1.6e-25 89.3 0.0 1.9e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.27 KPA38823.1 - 6e-71 234.5 1.9 6.3e-23 80.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPA38823.1 - 0.31 10.1 1.4 6.9 5.7 0.1 3.0 1 1 3 4 4 4 0 Gammaproteobacterial serine protease Zn_clus PF00172.18 KPA38824.1 - 0.002 18.2 10.4 0.0034 17.5 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PADR1 PF08063.12 KPA38824.1 - 0.44 10.4 3.3 0.81 9.5 3.3 1.3 1 0 0 1 1 1 0 PADR1 (NUC008) domain LSM PF01423.22 KPA38825.1 - 3.2e-21 74.8 0.4 3.9e-21 74.5 0.4 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 KPA38825.1 - 0.053 14.1 8.5 0.075 13.6 8.5 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pan3_PK PF18101.1 KPA38826.1 - 1.2e-60 203.5 0.1 1.8e-60 202.9 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KPA38826.1 - 8.3e-06 25.3 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain zf-CCCH PF00642.24 KPA38826.1 - 0.14 12.1 0.6 0.24 11.4 0.6 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UBA_4 PF14555.6 KPA38827.1 - 2.3e-10 40.1 0.4 4.7e-10 39.1 0.4 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KPA38827.1 - 3.9e-05 23.8 0.0 9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 UBX domain SUB1_ProdP9 PF18213.1 KPA38827.1 - 0.095 12.5 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Aa_trans PF01490.18 KPA38828.1 - 2.8e-31 108.6 32.3 3.2e-31 108.4 32.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KPA38828.1 - 0.0011 18.1 13.3 0.0011 18.1 13.3 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Tannase PF07519.11 KPA38829.1 - 1.6e-113 380.2 1.5 2e-113 379.8 1.5 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 KPA38829.1 - 0.072 12.7 0.2 0.66 9.6 0.1 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3237 PF11578.8 KPA38830.1 - 2.6e-25 89.0 0.1 6.1e-20 71.6 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) Ribosomal_L5_C PF00673.21 KPA38830.1 - 0.059 13.5 0.0 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 ribosomal L5P family C-terminus NACHT PF05729.12 KPA38831.1 - 0.13 12.2 0.0 0.45 10.4 0.0 1.9 2 1 0 2 2 2 0 NACHT domain DUF4201 PF13870.6 KPA38832.1 - 0.0084 15.9 2.9 0.015 15.1 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DHR10 PF18595.1 KPA38832.1 - 0.013 15.6 4.6 0.029 14.4 4.6 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain MAD PF05557.13 KPA38832.1 - 0.025 12.9 3.8 0.039 12.3 3.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Vps5 PF09325.10 KPA38832.1 - 0.046 13.3 2.7 0.33 10.5 2.7 2.0 1 1 1 2 2 2 0 Vps5 C terminal like CortBP2 PF09727.9 KPA38832.1 - 0.16 11.8 8.9 0.021 14.7 4.7 1.7 2 0 0 2 2 2 0 Cortactin-binding protein-2 V-SNARE PF05008.15 KPA38832.1 - 1.1 9.6 7.8 0.2 12.1 4.1 1.7 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF4407 PF14362.6 KPA38832.1 - 4.2 6.6 6.9 0.2 11.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4472 PF14739.6 KPA38832.1 - 6.2 7.6 10.2 0.31 11.8 4.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) DJ-1_PfpI PF01965.24 KPA38833.1 - 4.6e-14 52.6 0.0 6.2e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_transf_28 PF03033.20 KPA38834.1 - 1e-22 80.7 0.0 2.9e-22 79.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KPA38834.1 - 0.19 10.5 0.1 0.29 9.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Zn_clus PF00172.18 KPA38835.1 - 1.5e-09 37.8 10.8 2.6e-09 37.1 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA38835.1 - 3e-08 32.9 0.4 4.4e-08 32.3 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain dCache_2 PF08269.11 KPA38836.1 - 0.0016 17.7 0.1 0.002 17.4 0.1 1.1 1 0 0 1 1 1 1 Cache domain DUF2884 PF11101.8 KPA38836.1 - 0.0021 17.6 0.7 0.0026 17.3 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) Baculo_PEP_C PF04513.12 KPA38836.1 - 0.0054 16.8 2.3 0.0074 16.3 2.3 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 KPA38836.1 - 0.024 14.9 1.8 0.049 13.9 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) ApoLp-III PF07464.11 KPA38836.1 - 0.055 13.6 2.9 0.08 13.0 2.9 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Syntaxin-6_N PF09177.11 KPA38836.1 - 0.056 14.0 0.4 0.094 13.3 0.4 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal V-SNARE PF05008.15 KPA38836.1 - 0.12 12.7 1.6 1 9.8 0.2 2.2 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF2564 PF10819.8 KPA38836.1 - 0.52 10.7 5.7 2.4 8.6 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) Chromo PF00385.24 KPA38837.1 - 4.3e-05 23.3 2.0 7.8e-05 22.5 2.0 1.5 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3712 PF12505.8 KPA38839.1 - 6.2e-20 71.7 0.3 1.2e-19 70.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) Adaptin_N PF01602.20 KPA38840.1 - 3.4e-12 45.7 16.4 0.078 11.5 0.3 9.5 4 3 2 6 6 6 5 Adaptin N terminal region Vault_4 PF17796.1 KPA38840.1 - 0.00017 21.6 0.1 37 4.5 0.0 7.4 9 0 0 9 9 9 0 Major Vault Protein repeat domain RP853 PF17542.2 KPA38840.1 - 0.0011 18.1 8.3 0.64 9.1 0.0 4.6 5 0 0 5 5 5 2 Uncharacterized RP853 DUF3475 PF11961.8 KPA38840.1 - 0.0023 18.0 7.1 2.9 8.0 0.0 6.6 7 0 0 7 7 7 1 Domain of unknown function (DUF3475) AF-4 PF05110.13 KPA38840.1 - 0.0063 14.7 1.3 0.0088 14.2 1.3 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein TetR_C_29 PF17938.1 KPA38840.1 - 0.0068 16.5 1.6 14 5.8 0.0 6.0 8 0 0 8 8 8 1 Tetracyclin repressor-like, C-terminal domain LIN52 PF10044.9 KPA38840.1 - 0.028 15.1 5.3 31 5.3 0.0 7.5 4 2 5 10 10 10 0 Retinal tissue protein Serglycin PF04360.12 KPA38840.1 - 0.2 11.6 0.2 0.36 10.8 0.2 1.3 1 0 0 1 1 1 0 Serglycin DHC_N1 PF08385.12 KPA38840.1 - 0.23 10.1 0.8 14 4.1 0.1 3.7 3 0 0 3 3 3 0 Dynein heavy chain, N-terminal region 1 RPN6_N PF18055.1 KPA38840.1 - 0.44 10.9 8.4 5.8 7.3 0.1 4.9 5 0 0 5 5 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF4518 PF15008.6 KPA38840.1 - 4 6.5 15.0 93 2.1 0.0 7.7 6 3 2 9 9 9 0 Domain of unknown function (DUF4518) Ribosomal_L27_C PF18471.1 KPA38840.1 - 6.7 6.1 16.1 2.5 7.5 0.7 4.9 3 2 3 6 6 6 0 Ribosomal L27 protein C-terminal domain CRAL_TRIO PF00650.20 KPA38841.1 - 2.9e-41 140.9 0.0 5e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KPA38841.1 - 1.7e-12 47.3 0.0 5.9e-12 45.6 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KPA38841.1 - 2.1e-07 31.2 0.0 3.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3189 PF11385.8 KPA38841.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) p450 PF00067.22 KPA38842.1 - 4.6e-66 223.4 0.0 6.1e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase_3 PF13468.6 KPA38843.1 - 6.5e-17 62.2 0.0 1.1e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain PBECR4 PF18813.1 KPA38843.1 - 0.083 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 MatE PF01554.18 KPA38844.1 - 2.2e-49 167.2 28.2 3.7e-33 114.5 8.4 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KPA38844.1 - 9.9e-06 25.7 3.5 9.9e-06 25.7 3.5 4.1 3 2 2 5 5 5 1 Polysaccharide biosynthesis C-terminal domain HEXIM PF15313.6 KPA38845.1 - 0.17 12.0 0.2 0.27 11.4 0.2 1.2 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein VIT1 PF01988.19 KPA38845.1 - 0.2 11.5 7.8 0.61 9.9 1.6 2.5 2 0 0 2 2 2 0 VIT family AA_permease_2 PF13520.6 KPA38846.1 - 1.9e-59 201.6 56.7 2.4e-59 201.3 56.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA38846.1 - 4.7e-28 98.0 47.7 6.4e-28 97.6 47.7 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 KPA38846.1 - 0.83 9.7 7.8 20 5.2 0.7 3.5 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Annexin PF00191.20 KPA38847.1 - 1.5e-48 162.7 0.6 2.4e-14 53.1 0.0 4.2 4 0 0 4 4 4 4 Annexin DUF2255 PF10012.9 KPA38847.1 - 0.055 13.6 0.2 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) adh_short_C2 PF13561.6 KPA38848.1 - 5.1e-40 137.5 0.0 2.8e-39 135.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA38848.1 - 4.8e-35 120.8 0.0 6.4e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA38848.1 - 1.2e-10 41.6 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA38848.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA38848.1 - 6.6e-05 22.5 0.0 0.00031 20.3 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KPA38848.1 - 0.05 13.1 0.2 0.078 12.5 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 KPA38848.1 - 0.16 11.9 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding COesterase PF00135.28 KPA38849.1 - 8.3e-88 295.5 0.6 2e-73 248.0 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA38849.1 - 2.2e-07 31.0 0.1 3.7e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KPA38849.1 - 0.013 15.0 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase MDMPI_N PF11716.8 KPA38850.1 - 0.095 13.4 0.1 0.13 12.9 0.1 1.1 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Herpes_UL92 PF03048.14 KPA38852.1 - 1.1 9.0 3.2 0.34 10.7 0.1 1.7 2 0 0 2 2 2 0 UL92 family MFS_1 PF07690.16 KPA38853.1 - 5.4e-15 55.2 23.9 7.5e-15 54.7 23.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA38853.1 - 3.5e-06 26.2 9.4 5.3e-06 25.6 9.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KPA38853.1 - 0.02 14.2 10.3 0.029 13.7 10.3 1.2 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB CDC73_C PF05179.14 KPA38854.1 - 2e-54 183.5 0.0 3.9e-54 182.6 0.0 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Mito_carr PF00153.27 KPA38855.1 - 4.4e-61 202.8 1.1 1e-21 76.6 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPA38855.1 - 0.067 12.3 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease MT-A70 PF05063.14 KPA38856.1 - 3.6e-34 118.2 0.3 4.7e-34 117.8 0.3 1.1 1 0 0 1 1 1 1 MT-A70 Ribosomal_L23 PF00276.20 KPA38857.1 - 3.5e-12 46.5 0.0 7.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Mito_carr PF00153.27 KPA38859.1 - 1.2e-59 198.3 0.3 6.4e-21 74.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein AAA PF00004.29 KPA38860.1 - 3.9e-50 169.7 0.0 2.3e-38 131.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA38860.1 - 2e-11 43.5 0.4 3.1e-08 33.3 0.2 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KPA38860.1 - 2.5e-06 28.0 4.0 0.48 10.8 0.0 4.4 2 2 2 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.22 KPA38860.1 - 0.00047 20.5 0.0 0.33 11.4 0.0 3.6 4 0 0 4 4 3 1 RNA helicase AAA_14 PF13173.6 KPA38860.1 - 0.00082 19.4 0.0 0.6 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KPA38860.1 - 0.0015 18.5 0.0 0.78 9.7 0.0 3.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPA38860.1 - 0.0024 18.2 5.9 15 5.8 0.1 4.5 2 2 2 4 4 4 0 AAA domain AAA_7 PF12775.7 KPA38860.1 - 0.0044 16.5 0.0 3.9 7.0 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region RuvB_N PF05496.12 KPA38860.1 - 0.0063 16.3 0.0 0.029 14.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KPA38860.1 - 0.009 16.0 0.0 0.32 10.9 0.0 2.7 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_25 PF13481.6 KPA38860.1 - 0.016 14.8 0.6 34 3.9 0.1 3.4 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.6 KPA38860.1 - 0.019 15.2 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 KPA38860.1 - 0.02 15.0 0.0 0.17 12.0 0.0 2.4 3 0 0 3 3 3 0 Torsin TniB PF05621.11 KPA38860.1 - 0.049 13.0 0.5 1.6 8.1 0.1 3.0 2 1 1 3 3 3 0 Bacterial TniB protein AAA_23 PF13476.6 KPA38860.1 - 0.064 13.7 0.0 0.22 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KPA38860.1 - 0.11 12.8 0.0 1.1 9.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain Vps4_C PF09336.10 KPA38860.1 - 1 9.4 2.9 4.6 7.3 0.0 3.1 4 0 0 4 4 2 0 Vps4 C terminal oligomerisation domain NACHT PF05729.12 KPA38860.1 - 1.6 8.6 3.7 18 5.2 0.1 2.9 2 1 1 3 3 3 0 NACHT domain SMK-1 PF04802.15 KPA38861.1 - 1e-83 279.9 0.4 2.2e-83 278.8 0.4 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Importin_rep_4 PF18808.1 KPA38861.1 - 0.21 11.9 2.1 20 5.5 2.8 2.8 2 0 0 2 2 2 0 Importin repeat Glycos_transf_2 PF00535.26 KPA38863.1 - 1.5e-23 83.5 0.0 2.6e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KPA38863.1 - 1.6e-09 38.0 0.1 3.6e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KPA38863.1 - 2.1e-05 24.2 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KPA38863.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 LisH_TPL PF17814.1 KPA38863.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 LisH-like dimerisation domain SE PF08491.10 KPA38864.1 - 5.4e-90 301.2 0.0 7.4e-90 300.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KPA38864.1 - 2.7e-08 33.5 0.7 1.6e-05 24.4 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPA38864.1 - 2e-07 30.9 0.1 4.1e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA38864.1 - 3.9e-05 23.8 0.1 0.00012 22.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPA38864.1 - 9.3e-05 21.8 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KPA38864.1 - 0.00029 20.1 0.4 0.0022 17.2 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KPA38864.1 - 0.00064 19.0 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPA38864.1 - 0.00088 18.5 0.2 0.0016 17.6 0.1 1.4 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KPA38864.1 - 0.0013 18.2 0.1 0.0023 17.3 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA38864.1 - 0.0042 17.6 1.2 0.015 15.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KPA38864.1 - 0.033 13.8 0.1 0.06 13.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KPA38864.1 - 0.045 13.6 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KPA38864.1 - 0.054 12.2 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KPA38864.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 KPA38864.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KPA38864.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 KPA38864.1 - 0.096 11.5 0.1 7.9 5.2 0.1 2.6 3 0 0 3 3 3 0 Tryptophan halogenase CCDC168_N PF15804.5 KPA38865.1 - 0.016 15.0 0.4 0.03 14.2 0.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 168 Ferric_reduct PF01794.19 KPA38866.1 - 3.5e-24 85.3 14.8 3.5e-24 85.3 14.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KPA38866.1 - 2.7e-12 46.7 0.1 1.7e-07 31.3 0.1 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 KPA38866.1 - 3e-07 30.7 0.0 2.7e-05 24.3 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KPA38866.1 - 0.0035 18.0 0.0 0.0091 16.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF4079 PF13301.6 KPA38866.1 - 0.0083 16.3 3.9 1 9.5 1.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4079) MFS_1 PF07690.16 KPA38867.1 - 6e-17 61.6 47.2 1e-15 57.6 24.2 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA38867.1 - 3.6e-05 22.4 6.8 3.6e-05 22.4 6.8 2.5 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) ABC_membrane PF00664.23 KPA38868.1 - 2.8e-55 187.9 17.6 2.4e-33 116.0 2.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA38868.1 - 8.6e-51 172.0 3.1 6.8e-33 114.1 0.2 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KPA38868.1 - 6.7e-11 42.0 3.1 0.005 16.3 0.1 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPA38868.1 - 9.8e-09 35.4 0.2 0.037 13.9 0.0 3.9 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KPA38868.1 - 1.1e-06 28.7 0.6 0.015 15.3 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KPA38868.1 - 5.2e-05 23.7 0.6 0.023 15.1 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 KPA38868.1 - 5.9e-05 23.2 1.1 0.037 14.1 0.3 2.8 2 0 0 2 2 2 1 Dynamin family AAA_7 PF12775.7 KPA38868.1 - 0.00014 21.5 0.1 0.22 11.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 KPA38868.1 - 0.00016 21.3 0.2 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KPA38868.1 - 0.0007 20.1 0.0 0.43 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPA38868.1 - 0.00073 19.8 0.6 3.7 7.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KPA38868.1 - 0.00073 18.9 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 KPA38868.1 - 0.0021 17.8 2.6 1.1 9.0 0.1 3.3 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KPA38868.1 - 0.0024 17.8 0.0 0.63 9.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 KPA38868.1 - 0.0048 16.0 0.0 0.32 10.0 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_15 PF13175.6 KPA38868.1 - 0.0062 16.3 0.1 0.94 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 KPA38868.1 - 0.0089 16.2 0.7 9.6 6.5 0.3 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KPA38868.1 - 0.012 16.1 0.0 7.9 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KPA38868.1 - 0.015 14.6 0.1 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KPA38868.1 - 0.024 14.8 0.6 10 6.3 0.3 2.9 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KPA38868.1 - 0.031 14.5 0.2 3.8 7.7 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KPA38868.1 - 0.035 13.6 0.0 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TrwB_AAD_bind PF10412.9 KPA38868.1 - 0.049 12.5 0.6 3 6.6 0.2 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 KPA38868.1 - 0.06 12.9 1.0 0.45 10.1 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KPA38868.1 - 0.081 13.0 1.8 0.24 11.4 1.8 1.9 1 1 0 1 1 1 0 Helicase HerA, central domain TsaE PF02367.17 KPA38868.1 - 0.11 12.5 0.1 6.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KPA38868.1 - 0.13 12.0 0.0 18 4.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KPA38868.1 - 0.13 12.1 1.1 1 9.3 0.2 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 KPA38868.1 - 0.22 11.9 1.5 5.7 7.4 0.7 3.1 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Acetyltransf_8 PF13523.6 KPA38869.1 - 1.5e-24 86.3 0.2 3.4e-24 85.2 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 KPA38870.1 - 7.9e-200 663.9 0.0 1e-68 231.9 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KPA38870.1 - 7.5e-78 262.2 8.3 7.8e-17 61.1 0.2 8.5 7 3 1 8 8 8 6 Condensation domain PP-binding PF00550.25 KPA38870.1 - 6.7e-32 109.7 5.1 2.1e-08 34.4 0.1 6.3 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KPA38870.1 - 5.7e-10 40.0 1.5 0.016 16.1 0.1 4.1 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 KPA38870.1 - 2.4e-05 24.2 0.1 2.3 7.9 0.0 3.7 3 0 0 3 3 3 3 Wax ester synthase-like Acyl-CoA acyltransferase domain Baculo_PEP_C PF04513.12 KPA38870.1 - 1.5 8.8 8.4 1 9.4 0.4 4.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C2H2_2 PF12756.7 KPA38871.1 - 8.4e-27 93.5 5.7 1.9e-26 92.3 5.7 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KPA38871.1 - 0.35 11.8 4.7 3.2 8.8 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA38871.1 - 4.1 8.1 5.8 29 5.4 0.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type AAA_16 PF13191.6 KPA38872.1 - 3e-06 27.7 0.0 2e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Ank_2 PF12796.7 KPA38872.1 - 4e-06 27.3 0.0 1.3e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) NACHT PF05729.12 KPA38872.1 - 2.3e-05 24.4 0.2 6.7e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Ank_4 PF13637.6 KPA38872.1 - 3.2e-05 24.4 0.0 0.00012 22.5 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KPA38872.1 - 0.00066 20.0 0.5 0.51 10.9 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KPA38872.1 - 0.001 19.3 0.1 3.7 8.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat tRNA_lig_kinase PF08303.11 KPA38872.1 - 0.022 14.9 0.5 3.2 7.8 0.0 3.0 3 0 0 3 3 3 0 tRNA ligase kinase domain AAA_22 PF13401.6 KPA38872.1 - 0.025 14.9 0.0 0.091 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KPA38872.1 - 0.041 13.0 0.1 0.49 9.5 0.1 2.4 2 1 0 2 2 2 0 NB-ARC domain Ank_5 PF13857.6 KPA38872.1 - 0.15 12.4 0.0 0.74 10.2 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) zf-CCCH_6 PF18585.1 KPA38872.1 - 6.9 6.6 6.4 0.67 9.9 0.1 2.6 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 ATP-synt_ab PF00006.25 KPA38873.1 - 1.2e-72 244.0 0.0 1.8e-72 243.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KPA38873.1 - 3.9e-48 162.9 0.8 6.7e-48 162.2 0.8 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KPA38873.1 - 3.3e-15 56.3 2.8 8.5e-15 55.0 2.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L5_C PF00673.21 KPA38874.1 - 1.4e-22 79.6 0.0 2.1e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KPA38874.1 - 4.6e-20 71.7 1.3 8.2e-20 70.9 0.0 2.1 3 0 0 3 3 3 1 Ribosomal protein L5 LSM PF01423.22 KPA38875.1 - 3.8e-17 61.7 0.0 5.1e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain DnaJ PF00226.31 KPA38876.1 - 6.3e-20 71.1 0.5 9.9e-20 70.4 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 KPA38876.1 - 0.065 13.5 1.6 0.1 12.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 KPA38876.1 - 1.3 9.2 8.7 2.5 8.3 8.7 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Clr5 PF14420.6 KPA38877.1 - 1.8e-18 66.5 3.5 4e-18 65.4 3.5 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KPA38877.1 - 0.0026 18.0 2.5 0.015 15.5 2.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4692 PF15763.5 KPA38877.1 - 0.076 13.5 2.8 0.15 12.5 2.8 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF3782 PF12644.7 KPA38877.1 - 0.4 10.9 3.2 0.33 11.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) PITH PF06201.13 KPA38878.1 - 9.9e-36 123.2 0.0 1.5e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KPA38878.1 - 9.3e-26 89.8 0.0 1.5e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KPA38878.1 - 5.6e-07 30.0 0.1 2e-06 28.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KPA38878.1 - 2.8e-05 24.4 0.0 0.017 15.4 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KPA38878.1 - 0.00066 19.1 0.0 0.00094 18.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 KPA38878.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KPA38878.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin CorA PF01544.18 KPA38881.1 - 3.4e-09 36.4 2.0 4.9e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein APG6_N PF17675.1 KPA38881.1 - 0.028 15.0 1.1 0.028 15.0 1.1 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4094 PF13334.6 KPA38881.1 - 0.23 11.9 0.9 0.62 10.5 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) FlxA PF14282.6 KPA38881.1 - 0.27 11.2 2.2 0.65 10.0 2.2 1.5 1 0 0 1 1 1 0 FlxA-like protein BTB PF00651.31 KPA38882.1 - 0.0028 17.9 0.0 0.0043 17.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PRIMA1 PF16101.5 KPA38882.1 - 0.76 9.8 4.0 0.84 9.7 2.3 2.0 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1993 PF09351.10 KPA38884.1 - 9.1e-48 162.4 0.0 1e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Zn_clus PF00172.18 KPA38885.1 - 0.00013 22.0 10.9 0.00022 21.3 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA38885.1 - 0.0055 15.8 0.1 0.014 14.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain SMYLE_N PF18615.1 KPA38885.1 - 0.25 10.9 10.3 0.34 10.4 5.2 2.3 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Glyco_hydro_31 PF01055.26 KPA38886.1 - 1.2e-94 318.0 0.1 1.5e-94 317.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KPA38886.1 - 1.1e-12 48.0 0.1 9.3e-12 45.1 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KPA38886.1 - 0.0063 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Zn_clus PF00172.18 KPA38887.1 - 6.8e-08 32.5 12.4 1.3e-07 31.7 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran_CTD PF16326.5 KPA38887.1 - 0.034 14.4 0.4 0.12 12.7 0.1 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain Asp PF00026.23 KPA38888.1 - 2.2e-46 158.7 0.1 2.9e-46 158.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA38888.1 - 1.1e-05 25.7 0.7 0.00034 20.9 0.1 3.1 2 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPA38888.1 - 0.005 17.5 0.1 3 8.5 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KPA38888.1 - 0.012 16.1 0.1 2.8 8.6 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease GMC_oxred_N PF00732.19 KPA38889.1 - 4.4e-31 108.3 0.0 9.1e-31 107.3 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA38889.1 - 3.2e-13 50.4 0.0 5.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KPA38889.1 - 1.1e-07 31.8 0.5 0.0021 17.7 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA38889.1 - 2.7e-06 26.9 0.0 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA38889.1 - 5.1e-06 26.6 0.0 2e-05 24.7 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPA38889.1 - 5.8e-06 25.3 0.0 3.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KPA38889.1 - 9e-05 21.7 0.1 0.0093 15.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KPA38889.1 - 0.00032 20.0 0.0 0.0063 15.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPA38889.1 - 0.0004 19.9 0.0 0.016 14.5 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA38889.1 - 0.0024 18.4 0.3 0.17 12.5 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA38889.1 - 0.0065 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KPA38889.1 - 0.016 14.3 0.0 0.047 12.7 0.0 1.8 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 KPA38889.1 - 0.021 14.1 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 KPA38889.1 - 0.028 13.7 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KPA38889.1 - 0.056 13.4 0.2 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KPA38890.1 - 1.2e-46 159.6 0.0 1.6e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA38890.1 - 0.00027 20.3 0.0 0.0035 16.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA38890.1 - 0.00036 20.7 0.0 0.00084 19.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPA38890.1 - 0.0012 18.1 0.0 0.016 14.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA38890.1 - 0.0017 18.0 0.0 0.067 12.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA38890.1 - 0.0025 16.6 0.0 0.0089 14.8 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KPA38890.1 - 0.0056 15.8 0.1 0.086 11.9 0.0 2.5 2 1 1 3 3 3 1 FAD binding domain Thi4 PF01946.17 KPA38890.1 - 0.013 14.8 0.0 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 KPA38890.1 - 0.017 14.2 0.0 2.8 7.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPA38890.1 - 0.16 11.9 0.2 0.91 9.5 0.1 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.16 KPA38891.1 - 1.3e-25 90.1 50.2 1.3e-19 70.3 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA38891.1 - 3.9e-07 29.3 20.4 0.0011 17.9 3.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Pam17 PF08566.10 KPA38891.1 - 0.36 10.7 1.2 0.66 9.8 0.4 1.8 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 FAD_binding_3 PF01494.19 KPA38892.1 - 1e-63 215.8 0.0 1.4e-63 215.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KPA38892.1 - 5.5e-05 22.4 0.8 0.16 11.0 0.2 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KPA38892.1 - 6.1e-05 22.4 0.2 0.055 12.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA38892.1 - 0.00052 18.8 0.1 0.0096 14.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KPA38892.1 - 0.00082 18.7 0.0 0.0035 16.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA38892.1 - 0.0048 16.5 0.3 0.013 15.1 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA38892.1 - 0.0051 17.0 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPA38892.1 - 0.01 16.4 0.1 0.033 14.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA38892.1 - 0.14 12.1 0.6 9.3 6.2 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding DIT1_PvcA PF05141.12 KPA38893.1 - 2.5e-87 292.8 0.0 3.3e-87 292.5 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KPA38893.1 - 1.7e-21 77.2 0.0 3.2e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family WW_1 PF18507.1 KPA38893.1 - 0.17 11.6 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 WW domain Ank_2 PF12796.7 KPA38896.1 - 5.6e-15 55.7 0.3 8.5e-07 29.5 0.0 5.0 3 1 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA38896.1 - 1.5e-14 54.1 2.7 3.3e-06 27.5 0.0 6.4 4 3 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA38896.1 - 2.5e-05 24.3 6.1 5.5 7.9 0.0 6.9 6 1 1 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 KPA38896.1 - 7.2e-05 23.0 1.1 5.8 7.3 0.0 6.2 7 1 1 8 8 8 1 Ankyrin repeats (many copies) Ank PF00023.30 KPA38896.1 - 0.00025 21.3 1.9 97 3.7 0.0 6.4 6 0 0 6 6 6 0 Ankyrin repeat Mer2 PF09074.10 KPA38896.1 - 1.3 8.8 8.0 0.9 9.3 0.4 2.6 2 0 0 2 2 2 0 Mer2 Sugar_tr PF00083.24 KPA38897.1 - 7.8e-68 229.4 24.7 9.1e-68 229.2 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38897.1 - 5.8e-14 51.8 29.1 5.8e-14 51.8 29.1 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF3938 PF13074.6 KPA38897.1 - 0.098 12.9 4.8 0.54 10.5 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) SLATT_1 PF18181.1 KPA38897.1 - 0.19 11.7 0.1 0.54 10.2 0.1 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 SLATT_fungal PF18142.1 KPA38897.1 - 0.63 10.0 6.0 0.19 11.7 1.9 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Glyco_hydro_2_C PF02836.17 KPA38898.1 - 7.6e-81 271.5 0.1 1e-80 271.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KPA38898.1 - 1.3e-23 83.8 0.2 2.3e-23 83.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KPA38898.1 - 7.4e-10 39.5 0.0 1.8e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4434 PF14488.6 KPA38898.1 - 0.14 12.1 0.0 0.4 10.7 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Acetyltransf_1 PF00583.25 KPA38899.1 - 1.1e-12 48.2 0.0 1.4e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA38899.1 - 1.7e-12 47.4 0.0 2.4e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA38899.1 - 8e-09 35.8 0.0 1.2e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KPA38899.1 - 9.2e-05 23.1 0.0 0.00011 22.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KPA38899.1 - 0.00039 20.6 0.0 0.00052 20.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA38899.1 - 0.0019 18.1 0.0 0.0047 16.9 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KPA38899.1 - 0.011 15.9 0.1 0.022 14.9 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Zn_clus PF00172.18 KPA38900.1 - 2.3e-09 37.2 11.7 4.3e-09 36.3 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA38900.1 - 0.00086 18.4 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.16 KPA38901.1 - 8e-42 143.9 1.0 1e-41 143.5 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.9 KPA38901.1 - 0.039 13.9 0.1 0.065 13.2 0.1 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Fungal_trans_2 PF11951.8 KPA38902.1 - 3.3e-06 26.2 4.4 8e-06 24.9 3.3 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF5056 PF16479.5 KPA38902.1 - 0.024 14.9 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) Rick_17kDa_Anti PF05433.15 KPA38903.1 - 4.2e-06 26.5 16.2 7.2e-06 25.8 16.2 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF456 PF04306.13 KPA38903.1 - 0.041 14.2 0.2 0.06 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 KPA38903.1 - 0.11 12.5 16.0 0.22 11.5 16.0 1.5 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KPA38903.1 - 0.21 11.3 19.2 0.48 10.2 19.2 1.6 1 1 0 1 1 1 0 YMGG-like Gly-zipper DUF5316 PF17247.2 KPA38903.1 - 0.53 10.3 0.1 0.53 10.3 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5316) TraT PF05818.12 KPA38903.1 - 0.6 9.8 8.9 0.47 10.1 7.3 1.6 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein Sugar_tr PF00083.24 KPA38904.1 - 6.8e-111 371.3 23.8 7.7e-111 371.1 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38904.1 - 5e-22 78.3 33.7 7.1e-19 67.9 11.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA38904.1 - 9.9e-08 31.0 17.4 9.4e-05 21.1 0.2 2.8 2 1 0 3 3 3 2 MFS/sugar transport protein COesterase PF00135.28 KPA38905.1 - 3.8e-73 247.1 0.0 4.8e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA38905.1 - 1.1e-07 31.9 0.0 0.0085 16.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF325 PF03804.13 KPA38905.1 - 0.097 12.7 0.0 0.34 11.0 0.0 1.9 2 0 0 2 2 2 0 Viral proteins of unknown function Fungal_trans_2 PF11951.8 KPA38906.1 - 3.8e-08 32.6 4.9 0.00011 21.2 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 KPA38907.1 - 5e-33 114.5 34.0 5.6e-32 111.0 36.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPA38907.1 - 7.1e-05 22.3 6.3 7.1e-05 22.3 6.3 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Pox_A14 PF05767.12 KPA38907.1 - 0.048 13.8 1.7 3.7 7.8 0.0 3.5 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF2254 PF10011.9 KPA38907.1 - 1.9 7.2 5.5 8.1 5.1 5.4 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) p450 PF00067.22 KPA38908.1 - 7.6e-77 259.0 0.0 1.1e-76 258.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KPA38908.1 - 2.7e-26 92.5 0.0 5e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KPA38908.1 - 1.4e-17 64.3 0.0 2.5e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KPA38908.1 - 8.2e-07 29.6 0.0 2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cytochrom_B561 PF03188.16 KPA38908.1 - 0.0085 16.2 1.4 0.018 15.2 1.4 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 NAD_binding_6 PF08030.12 KPA38908.1 - 0.082 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain ScsC_N PF18312.1 KPA38908.1 - 0.14 12.0 0.3 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain DUF1129 PF06570.11 KPA38908.1 - 0.27 10.7 0.5 0.52 9.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2417 PF10329.9 KPA38908.1 - 1.3 8.4 7.0 2.2 7.6 2.1 2.4 1 1 1 2 2 2 0 Region of unknown function (DUF2417) ThrE PF06738.12 KPA38908.1 - 1.3 8.3 6.8 3 7.1 6.2 1.9 2 0 0 2 2 2 0 Putative threonine/serine exporter AATase PF07247.12 KPA38909.1 - 4.7e-14 51.8 0.0 2.5e-11 42.8 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase WES_acyltransf PF03007.16 KPA38909.1 - 5.8e-05 23.0 0.1 0.00013 21.8 0.1 1.6 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF2389 PF09493.10 KPA38909.1 - 0.012 16.2 0.0 0.04 14.6 0.0 1.9 1 0 0 1 1 1 0 Tryptophan-rich protein (DUF2389) Condensation PF00668.20 KPA38909.1 - 0.02 13.6 0.0 0.66 8.6 0.0 2.1 2 0 0 2 2 2 0 Condensation domain Tri3 PF07428.11 KPA38909.1 - 0.063 12.2 0.0 6.4 5.6 0.0 2.1 2 0 0 2 2 2 0 15-O-acetyltransferase Tri3 Gpr1_Fun34_YaaH PF01184.19 KPA38910.1 - 5.7e-60 202.5 8.5 8e-60 202.0 8.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family F-box-like PF12937.7 KPA38910.1 - 0.0025 17.7 1.9 0.01 15.7 1.9 2.1 1 1 0 1 1 1 1 F-box-like DUF3899 PF13038.6 KPA38910.1 - 2.6 8.6 5.4 5.9 7.5 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) F-box PF00646.33 KPA38911.1 - 0.00051 19.8 0.2 0.0012 18.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KPA38911.1 - 0.0018 18.1 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF2457 PF10446.9 KPA38911.1 - 0.0047 16.1 14.5 0.0098 15.1 14.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) RRN3 PF05327.11 KPA38911.1 - 0.16 10.5 3.6 0.23 9.9 3.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Roughex PF06020.11 KPA38911.1 - 0.54 9.3 7.2 0.9 8.6 7.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein BUD22 PF09073.10 KPA38911.1 - 1.5 8.1 14.7 2.8 7.2 14.7 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KPA38911.1 - 1.8 6.7 5.9 2.6 6.2 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 KPA38911.1 - 2.6 7.7 5.1 4.7 6.8 5.1 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RPE65 PF03055.15 KPA38912.1 - 2e-105 353.7 0.0 2.3e-105 353.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein AIRC PF00731.20 KPA38913.1 - 7.3e-58 194.4 0.4 2e-57 192.9 0.4 1.8 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KPA38913.1 - 5.3e-48 162.8 0.0 1.3e-47 161.5 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain PurK_C PF17769.1 KPA38913.1 - 4.3e-13 48.7 0.0 9.4e-13 47.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KPA38913.1 - 1.8e-06 27.6 0.0 4.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KPA38913.1 - 0.00031 20.3 1.0 0.00045 19.8 0.1 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain XdhC_C PF13478.6 KPA38913.1 - 0.0024 18.4 0.2 1.2 9.6 0.0 2.9 3 0 0 3 3 3 1 XdhC Rossmann domain DUF1297 PF06973.12 KPA38913.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) PrpR_N PF06506.11 KPA38913.1 - 0.13 11.8 0.1 0.36 10.4 0.1 1.8 1 0 0 1 1 1 0 Propionate catabolism activator Cutinase PF01083.22 KPA38914.1 - 8.6e-51 172.4 3.3 1.1e-50 172.1 3.3 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPA38914.1 - 5.4e-07 29.4 0.1 7.7e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Lipase_2 PF01674.18 KPA38914.1 - 0.052 13.1 0.6 0.082 12.4 0.6 1.3 1 0 0 1 1 1 0 Lipase (class 2) LIP PF03583.14 KPA38914.1 - 0.67 9.2 4.1 3 7.1 0.0 2.4 3 0 0 3 3 3 0 Secretory lipase Iso_dh PF00180.20 KPA38915.1 - 1.5e-102 343.3 0.0 1.9e-102 343.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase adh_short_C2 PF13561.6 KPA38916.1 - 3.6e-48 164.2 0.1 1.2e-34 119.9 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA38916.1 - 3e-39 134.5 0.2 4e-39 134.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA38916.1 - 2.1e-07 31.0 0.0 3.7e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA38916.1 - 0.0015 18.0 0.3 0.0023 17.5 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KPA38916.1 - 0.019 15.2 0.1 0.033 14.5 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 KPA38916.1 - 0.04 14.6 0.2 0.24 12.1 0.1 1.9 1 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KPA38916.1 - 0.055 13.3 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KPA38916.1 - 0.1 12.6 0.4 0.2 11.7 0.4 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 KPA38916.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Aldedh PF00171.22 KPA38917.1 - 1.3e-152 508.6 0.0 1.4e-152 508.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPA38917.1 - 0.00082 18.9 0.0 0.0025 17.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) PEP_mutase PF13714.6 KPA38917.1 - 0.043 13.3 0.1 0.084 12.3 0.1 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Bul1_N PF04425.12 KPA38918.1 - 0.00018 20.4 0.0 0.00052 18.9 0.0 1.8 2 0 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.12 KPA38918.1 - 0.00039 19.9 0.6 0.00055 19.4 0.6 1.2 1 0 0 1 1 1 1 Bul1 C terminus Sugar_tr PF00083.24 KPA38920.1 - 1.3e-107 360.5 17.8 1.5e-107 360.3 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38920.1 - 7.6e-26 90.9 13.0 7.6e-26 90.9 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.11 KPA38920.1 - 0.35 10.3 4.5 7.1 6.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Epimerase PF01370.21 KPA38921.1 - 3.5e-14 52.8 0.0 4.8e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPA38921.1 - 2.6e-12 47.0 0.0 4.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KPA38921.1 - 5e-12 45.4 0.0 8.2e-12 44.7 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KPA38921.1 - 1.4e-08 34.6 0.0 2.4e-08 33.8 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KPA38921.1 - 1.5e-08 34.1 0.0 0.0047 16.1 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KPA38921.1 - 1.4e-07 31.4 0.1 2.6e-06 27.2 0.2 2.4 2 1 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 KPA38921.1 - 0.00012 21.3 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KPA38921.1 - 0.00043 19.8 0.1 0.00082 18.9 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KPA38921.1 - 0.0005 19.3 0.0 0.00071 18.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KPA38921.1 - 0.0035 17.3 0.3 0.055 13.4 0.3 2.1 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.18 KPA38922.1 - 2.2e-09 36.8 9.4 9.6e-09 34.6 4.6 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain ESSS PF10183.9 KPA38922.1 - 0.082 13.1 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PIEZO PF15917.5 KPA38922.1 - 0.085 12.3 0.3 0.13 11.7 0.3 1.2 1 0 0 1 1 1 0 Piezo MR_MLE_C PF13378.6 KPA38923.1 - 1.4e-47 162.1 0.0 2e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KPA38923.1 - 3.6e-05 24.0 0.0 7.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KPA38923.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus RicinB_lectin_2 PF14200.6 KPA38924.1 - 3.8e-09 37.2 0.8 3.8e-09 37.2 0.8 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like UPF0242 PF06785.11 KPA38924.1 - 0.0049 17.0 14.7 0.0049 17.0 14.7 2.3 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 KPA38924.1 - 0.012 15.9 31.0 0.012 15.9 31.0 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1643 PF07799.12 KPA38924.1 - 0.1 12.8 0.8 0.24 11.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1643) Sec23_trunk PF04811.15 KPA38924.1 - 0.19 11.3 1.2 0.34 10.4 1.2 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain ADIP PF11559.8 KPA38924.1 - 0.54 10.3 37.1 0.12 12.5 12.0 3.6 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Rootletin PF15035.6 KPA38924.1 - 2.1 8.3 27.7 17 5.4 21.2 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion SLATT_5 PF18160.1 KPA38924.1 - 3.1 7.1 4.4 6.2 6.1 4.4 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 EzrA PF06160.12 KPA38924.1 - 4.5 5.3 26.9 2.2 6.4 12.2 1.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA FlaC_arch PF05377.11 KPA38924.1 - 7.5 7.0 6.5 13 6.3 0.1 3.1 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) RRP14 PF15459.6 KPA38926.1 - 0.081 13.5 2.9 0.29 11.8 1.0 2.4 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 DivIC PF04977.15 KPA38926.1 - 0.13 12.0 5.1 3 7.7 0.8 2.8 3 0 0 3 3 3 0 Septum formation initiator ASD2 PF08687.11 KPA38927.1 - 0.17 11.4 6.7 0.46 10.0 6.7 1.7 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 ATG16 PF08614.11 KPA38927.1 - 0.43 10.8 9.8 1.4 9.1 9.3 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Mito_carr PF00153.27 KPA38928.1 - 4.5e-20 71.4 3.6 1.2e-08 34.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein RskA PF10099.9 KPA38928.1 - 0.32 11.3 1.2 2.8 8.2 0.1 2.5 2 1 0 2 2 2 0 Anti-sigma-K factor rskA DLH PF01738.18 KPA38929.1 - 1.5e-26 93.3 0.0 1.8e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family adh_short_C2 PF13561.6 KPA38930.1 - 7.3e-60 202.4 0.1 8.5e-60 202.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA38930.1 - 5.1e-46 156.6 0.1 6.6e-46 156.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA38930.1 - 1.7e-15 57.4 0.0 2.8e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KPA38930.1 - 0.00074 18.6 0.1 0.0018 17.3 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HATPase_c PF02518.26 KPA38930.1 - 0.13 12.8 0.0 0.4 11.2 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_43 PF04616.14 KPA38931.1 - 6.8e-69 232.4 3.5 8.8e-69 232.0 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KPA38931.1 - 1.3e-20 74.0 0.0 2.1e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Zn_clus PF00172.18 KPA38932.1 - 1.7e-07 31.2 13.2 3.3e-07 30.3 13.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA38932.1 - 0.00035 19.7 0.3 0.00086 18.4 0.1 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain E2F_TDP PF02319.20 KPA38932.1 - 0.0029 17.6 0.0 0.0081 16.2 0.0 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain SnoaL PF07366.12 KPA38933.1 - 0.0021 17.8 0.0 0.0045 16.8 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KPA38933.1 - 0.061 14.0 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Pyr_redox_3 PF13738.6 KPA38934.1 - 3.6e-17 62.6 0.0 2.1e-16 60.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPA38934.1 - 3.3e-15 55.5 0.0 5e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPA38934.1 - 4.2e-12 45.9 0.0 6.2e-10 38.7 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPA38934.1 - 5.3e-11 42.3 0.0 8.7e-09 35.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA38934.1 - 3.2e-06 27.3 0.1 3.6e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPA38934.1 - 6e-05 22.4 0.3 0.00019 20.8 0.1 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KPA38934.1 - 0.00017 21.3 0.0 0.08 12.5 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPA38934.1 - 0.0013 18.7 0.1 0.027 14.5 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Mqo PF06039.15 KPA38934.1 - 0.0038 15.8 0.0 0.2 10.1 0.0 2.7 2 1 1 3 3 3 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 KPA38934.1 - 0.01 16.3 2.2 3.9 8.1 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA38934.1 - 0.018 13.8 0.0 2.3 6.8 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KPA38934.1 - 0.093 11.8 0.3 0.37 9.8 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KPA38934.1 - 0.11 11.5 0.8 4.1 6.4 0.6 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Na_H_Exchanger PF00999.21 KPA38935.1 - 1.2e-11 44.0 8.5 5.2e-11 41.9 1.3 2.0 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family DUF3435 PF11917.8 KPA38936.1 - 2.5e-15 56.4 0.0 3.5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Chromo PF00385.24 KPA38936.1 - 7.5e-06 25.8 3.3 0.023 14.6 0.6 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain zf-C2H2_jaz PF12171.8 KPA38936.1 - 0.19 12.0 5.0 0.08 13.3 0.6 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPA38936.1 - 1.7 9.1 5.9 0.79 10.2 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF3723 PF12520.8 KPA38937.1 - 4.5e-57 193.9 0.1 1.1e-55 189.3 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) Death PF00531.22 KPA38937.1 - 0.089 13.0 0.0 0.31 11.2 0.0 1.9 1 0 0 1 1 1 0 Death domain Pkinase PF00069.25 KPA38940.1 - 2.5e-26 92.6 0.0 3.1e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA38940.1 - 1.2e-18 67.4 0.0 1e-17 64.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPA38940.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KPA38940.1 - 0.0019 17.6 0.0 0.013 14.8 0.0 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KPA38940.1 - 0.0099 15.8 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Methyltransf_33 PF10017.9 KPA38946.1 - 2.6e-32 112.2 0.0 8e-32 110.6 0.0 1.8 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent PAS_9 PF13426.7 KPA38946.1 - 0.1 12.9 0.1 1.4 9.3 0.0 2.7 3 0 0 3 3 3 0 PAS domain B12-binding PF02310.19 KPA38947.1 - 0.0012 18.8 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain FAA_hydrolase PF01557.18 KPA38948.1 - 7.3e-56 189.3 0.0 9.8e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3500 PF12006.8 KPA38949.1 - 3.9e-98 328.6 0.0 3.3e-96 322.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3500) GST_C PF00043.25 KPA38950.1 - 1.5e-06 28.4 0.0 2.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA38950.1 - 6.5e-05 23.1 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPA38950.1 - 0.00015 22.0 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPA38950.1 - 0.017 15.5 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ATPase_gene1 PF09527.10 KPA38950.1 - 0.028 14.6 1.0 0.42 10.8 0.1 2.3 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter GST_N PF02798.20 KPA38950.1 - 0.072 13.4 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPA38950.1 - 0.11 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Arylesterase PF01731.20 KPA38951.1 - 3.7e-06 27.0 0.2 4e-05 23.7 0.0 2.6 2 1 0 2 2 2 1 Arylesterase NmrA PF05368.13 KPA38952.1 - 2.4e-21 76.4 0.0 4.6e-21 75.5 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA38952.1 - 2.9e-18 66.4 0.0 4.9e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KPA38952.1 - 1.4e-05 25.1 0.0 2.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KPA38952.1 - 3.2e-05 24.2 0.1 6.6e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KPA38952.1 - 0.0002 21.8 0.1 0.00034 21.0 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KPA38952.1 - 0.003 17.0 0.1 0.56 9.6 0.1 2.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KPA38952.1 - 0.0037 17.4 0.2 0.0071 16.5 0.2 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.19 KPA38952.1 - 0.024 14.0 0.1 0.071 12.4 0.1 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KPA38952.1 - 0.092 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Thump_like PF18096.1 KPA38952.1 - 0.16 11.9 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 THUMP domain-like Thioredoxin PF00085.20 KPA38953.1 - 4.9e-24 84.3 0.1 6.2e-24 84.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KPA38953.1 - 2.1e-09 37.2 0.1 2.2e-09 37.1 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KPA38953.1 - 3.9e-07 30.5 0.0 7.1e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KPA38953.1 - 1.9e-05 24.4 0.0 2.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KPA38953.1 - 0.00044 20.4 0.0 0.00064 19.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KPA38953.1 - 0.013 15.8 0.0 0.71 10.2 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like HyaE PF07449.11 KPA38953.1 - 0.019 15.0 0.0 0.027 14.4 0.0 1.5 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 KPA38953.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 Glutaredoxin Redoxin PF08534.10 KPA38953.1 - 0.06 13.1 0.1 0.14 11.9 0.1 1.6 1 1 1 2 2 2 0 Redoxin Thioredoxin_5 PF13743.6 KPA38953.1 - 0.11 12.2 0.1 0.16 11.6 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin Thioredoxin PF00085.20 KPA38954.1 - 2.8e-26 91.5 0.0 3.3e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KPA38954.1 - 1.9e-05 25.1 0.0 8.6e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KPA38954.1 - 3.2e-05 23.7 0.0 3.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KPA38954.1 - 0.00011 21.7 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KPA38954.1 - 0.00016 21.9 0.0 0.00035 20.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KPA38954.1 - 0.00022 20.9 0.0 0.00029 20.6 0.0 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KPA38954.1 - 0.0014 18.6 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KPA38954.1 - 0.0019 18.4 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 KPA38954.1 - 0.09 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Abhydrolase_1 PF00561.20 KPA38955.1 - 6.2e-13 49.0 0.1 1.5e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA38955.1 - 1.7e-06 27.5 0.1 6.8e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF4448 PF14610.6 KPA38956.1 - 0.00016 21.5 0.0 0.00035 20.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) LapA_dom PF06305.11 KPA38956.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HET PF06985.11 KPA38957.1 - 1.4e-33 116.3 0.0 2.9e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF5071 PF16804.5 KPA38958.1 - 2.2e-22 79.5 1.8 3e-22 79.1 0.2 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF5071) DUF5005 PF16396.5 KPA38958.1 - 0.012 14.4 0.3 0.74 8.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5005) DUF3425 PF11905.8 KPA38959.1 - 7.4e-15 55.0 0.0 2.6e-14 53.2 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) CCDC144C PF14915.6 KPA38959.1 - 0.015 14.5 5.6 0.035 13.2 4.8 1.9 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region bZIP_1 PF00170.21 KPA38959.1 - 0.021 14.9 9.8 0.021 14.9 9.8 2.6 3 0 0 3 3 3 0 bZIP transcription factor TipAS PF07739.13 KPA38959.1 - 0.14 12.7 0.1 0.3 11.7 0.1 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain LXG PF04740.12 KPA38959.1 - 0.33 10.6 2.0 0.63 9.7 2.0 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily NARP1 PF12569.8 KPA38959.1 - 0.44 9.4 4.3 0.58 9.0 4.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF5320 PF17253.2 KPA38959.1 - 1.1 10.3 2.5 1 10.5 0.9 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Beta_elim_lyase PF01212.21 KPA38960.1 - 3.7e-39 134.8 0.0 4.7e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KPA38960.1 - 9.7e-08 31.6 0.0 1.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPA38960.1 - 2.7e-05 23.3 0.1 3.5e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KPA38960.1 - 0.0019 17.6 0.4 0.0034 16.8 0.4 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CMAS PF02353.20 KPA38961.1 - 2.7e-59 200.7 0.3 3.3e-59 200.4 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KPA38961.1 - 6.7e-08 33.1 0.0 1.8e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA38961.1 - 6e-07 29.4 0.0 9.6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA38961.1 - 0.025 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 KPA38961.1 - 0.17 11.6 0.0 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ApbA PF02558.16 KPA38962.1 - 1e-35 122.6 0.2 1.3e-35 122.2 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KPA38962.1 - 3.3e-29 101.6 0.2 8.8e-29 100.2 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 KPA38962.1 - 0.001 19.3 0.1 0.0019 18.4 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 KPA38962.1 - 0.094 12.1 0.0 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 ThiF family HRXXH PF13933.6 KPA38963.1 - 2.8e-108 361.1 0.6 3.5e-108 360.8 0.6 1.1 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KPA38963.1 - 2.2e-08 34.8 2.0 3.1e-08 34.3 0.3 2.0 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase DUF4611 PF15387.6 KPA38963.1 - 0.27 11.5 3.5 0.33 11.2 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MR_MLE_C PF13378.6 KPA38964.1 - 1e-54 185.4 0.0 1.4e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KPA38964.1 - 3.8e-20 72.3 0.0 7.4e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MFS_1 PF07690.16 KPA38965.1 - 1.4e-40 139.4 57.3 6.3e-35 120.7 33.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA38965.1 - 0.0055 15.6 28.1 0.059 12.2 22.7 3.2 1 1 1 2 2 2 2 Sugar (and other) transporter Sugar_tr PF00083.24 KPA38966.1 - 5.6e-21 74.9 6.6 6.3e-21 74.8 6.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter FUSC-like PF12805.7 KPA38966.1 - 0.2 10.7 0.5 0.28 10.2 0.5 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS LptF_LptG PF03739.14 KPA38966.1 - 3.9 6.2 7.7 0.17 10.7 2.2 1.5 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG HALZ PF02183.18 KPA38970.1 - 0.0019 18.3 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper THB PF18362.1 KPA38970.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Tri-helix bundle domain CEBP1_N PF16368.5 KPA38972.1 - 0.056 13.0 0.0 0.06 12.9 0.0 1.0 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus PheRS_DBD1 PF18552.1 KPA38972.1 - 0.064 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 PheRS DNA binding domain 1 RbsD_FucU PF05025.13 KPA38972.1 - 0.07 13.6 0.1 0.16 12.4 0.1 1.6 1 1 0 1 1 1 0 RbsD / FucU transport protein family RNase_H PF00075.24 KPA38973.1 - 1.1e-08 35.4 0.0 3.6e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KPA38973.1 - 0.0074 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like DUF2914 PF11141.8 KPA38976.1 - 0.13 12.0 0.6 0.31 10.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) DUF3723 PF12520.8 KPA38977.1 - 2e-27 96.1 0.0 2.8e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Cellulase PF00150.18 KPA38978.1 - 4.1e-30 105.2 2.9 4.1e-30 105.2 2.9 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KPA38978.1 - 4.6e-06 26.5 1.0 8.1e-06 25.7 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Cellulase PF00150.18 KPA38980.1 - 2.5e-33 115.7 0.4 3.8e-33 115.1 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sugar_tr PF00083.24 KPA38982.1 - 1.4e-78 264.8 27.3 1.6e-78 264.6 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38982.1 - 1.1e-19 70.6 45.2 1.6e-16 60.2 30.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Peptidase_S10 PF00450.22 KPA38983.1 - 9.3e-41 140.6 0.0 7.6e-40 137.6 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase Ig_GlcNase PF18368.1 KPA38983.1 - 1.5e-26 92.5 0.2 4.4e-26 91.1 0.2 1.9 1 0 0 1 1 1 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 KPA38983.1 - 2e-13 50.9 0.1 4.8e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KPA38983.1 - 2.4e-06 27.2 0.2 9.6e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 KPA38983.1 - 2.2e-05 24.9 0.0 9.5e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain BetaGal_dom4_5 PF13364.6 KPA38983.1 - 0.073 13.6 0.4 0.29 11.7 0.4 2.0 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Sugar_tr PF00083.24 KPA38985.1 - 3.4e-56 191.0 21.2 4.3e-56 190.7 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA38985.1 - 1.9e-22 79.7 37.1 1.9e-22 79.7 37.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA38985.1 - 0.00045 18.9 4.7 0.00045 18.9 4.7 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KPA38985.1 - 1 8.1 19.6 2.1 7.1 7.3 2.6 2 1 0 2 2 2 0 MFS_1 like family DUF4387 PF14330.6 KPA38986.1 - 2.3e-33 114.8 0.0 5.2e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 KPA38986.1 - 5.9e-12 45.0 0.0 1.1e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA KH_1 PF00013.29 KPA38987.1 - 2.8e-42 142.4 5.3 1.1e-17 63.5 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KPA38987.1 - 4.4e-13 48.9 1.5 0.0037 17.0 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KPA38987.1 - 2.1e-08 33.9 0.5 0.054 13.4 0.0 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 KPA38987.1 - 4.1e-06 26.7 0.0 0.00055 19.9 0.0 2.6 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 KPA38987.1 - 0.00034 20.6 7.7 0.32 11.1 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain ABM PF03992.16 KPA38988.1 - 2.1e-05 24.5 0.0 0.0046 17.0 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Exo_endo_phos PF03372.23 KPA38989.1 - 1.6e-12 47.5 0.2 2.5e-12 46.8 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sensor PF13796.6 KPA38989.1 - 0.026 14.6 0.1 0.054 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative sensor Pkinase PF00069.25 KPA38990.1 - 5.7e-37 127.5 0.0 2.5e-31 109.0 0.0 3.2 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA38990.1 - 2.9e-16 59.5 0.0 6.4e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPA38990.1 - 0.0031 17.5 0.8 0.016 15.2 0.6 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KPA38990.1 - 0.013 14.4 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KPA38990.1 - 0.014 14.2 0.8 0.024 13.4 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase NPL PF17800.1 KPA38991.1 - 1.5e-34 118.7 1.7 1.5e-34 118.7 1.7 2.1 2 1 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 KPA38991.1 - 2.1e-31 108.1 0.0 8.7e-31 106.1 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Atg31 PF09795.9 KPA38991.1 - 6.7 6.7 11.1 1.6 8.7 2.0 2.7 2 0 0 2 2 2 0 Autophagy-related protein 31 Glyco_trans_2_3 PF13632.6 KPA38992.1 - 2.2e-16 60.4 0.0 6.1e-16 58.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DJ-1_PfpI PF01965.24 KPA38992.1 - 3.3e-11 43.3 0.0 6.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family FmiP_Thoc5 PF09766.9 KPA38993.1 - 3.1e-31 109.0 15.2 3.9e-31 108.7 15.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Casc1_N PF15927.5 KPA38993.1 - 0.0074 16.0 7.8 0.0074 16.0 7.8 1.9 2 0 0 2 2 2 1 Cancer susceptibility candidate 1 N-terminus SPATA1_C PF15743.5 KPA38993.1 - 0.0074 16.4 8.9 0.0077 16.3 4.3 2.2 2 0 0 2 2 2 1 Spermatogenesis-associated C-terminus DUF3450 PF11932.8 KPA38993.1 - 0.056 12.7 15.4 0.027 13.8 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) K-box PF01486.17 KPA38993.1 - 0.067 13.4 0.8 0.067 13.4 0.8 2.5 2 1 0 2 2 2 0 K-box region DUF4200 PF13863.6 KPA38993.1 - 0.37 11.2 12.3 0.81 10.1 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Mod_r PF07200.13 KPA38993.1 - 1.5 8.9 13.3 1.7 8.7 4.5 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4140 PF13600.6 KPA38993.1 - 3.2 8.3 7.0 23 5.5 2.5 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3958 PF13125.6 KPA38993.1 - 3.3 8.0 15.5 14 5.9 10.6 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3958) DivIC PF04977.15 KPA38993.1 - 4 7.3 11.5 4.5 7.1 0.3 2.7 3 0 0 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 KPA38993.1 - 4.9 6.4 8.3 7.3 5.8 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HlyIII PF03006.20 KPA38994.1 - 2.6e-56 190.8 17.3 3.3e-56 190.5 17.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related RabGAP-TBC PF00566.18 KPA38995.1 - 8.5e-33 113.8 0.0 3.1e-27 95.6 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Sulfate_transp PF00916.20 KPA38996.1 - 5.3e-108 361.2 20.0 6.8e-108 360.8 20.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KPA38996.1 - 7.7e-08 32.0 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KPA38996.1 - 2e-05 24.9 5.5 2e-05 24.9 5.5 3.3 2 2 0 2 2 2 1 Molybdate transporter of MFS superfamily DUF3810 PF12725.7 KPA38996.1 - 0.15 11.4 0.3 0.34 10.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) WLM PF08325.10 KPA38997.1 - 1e-27 97.4 1.0 1.6e-27 96.9 0.1 1.8 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 KPA38997.1 - 7.3e-08 32.7 1.1 1.9e-07 31.3 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.18 KPA38997.1 - 0.071 12.4 10.8 0.045 13.1 2.8 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Ndc1_Nup PF09531.10 KPA38997.1 - 3.2 6.3 4.5 4.3 5.9 4.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SelP_N PF04592.14 KPA38998.1 - 1.6 8.1 11.1 1.8 7.9 11.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region adh_short PF00106.25 KPA38999.1 - 2e-05 24.1 0.0 2.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA38999.1 - 0.00026 20.6 0.1 0.00033 20.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.17 KPA38999.1 - 0.0099 16.4 0.1 0.014 16.0 0.1 1.2 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KPA38999.1 - 0.032 13.6 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KPA38999.1 - 0.17 11.9 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PHO4 PF01384.20 KPA39000.1 - 1.3e-110 369.6 6.4 1.6e-110 369.4 6.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tim17 PF02466.19 KPA39000.1 - 0.0036 17.7 2.3 0.0036 17.7 2.3 3.1 3 2 0 3 3 3 1 Tim17/Tim22/Tim23/Pmp24 family p450 PF00067.22 KPA39001.1 - 1.8e-53 181.9 0.0 3.3e-53 181.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2353 PF09789.9 KPA39003.1 - 0.02 14.3 4.0 0.026 13.9 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) RRF PF01765.19 KPA39003.1 - 0.044 13.7 2.8 0.056 13.4 2.8 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Ufd2P_core PF10408.9 KPA39003.1 - 0.095 11.3 0.5 0.12 11.0 0.5 1.0 1 0 0 1 1 1 0 Ubiquitin elongating factor core SLATT_5 PF18160.1 KPA39003.1 - 0.44 9.8 2.1 0.56 9.5 2.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Cupin_4 PF08007.12 KPA39004.1 - 0.038 13.5 1.3 0.07 12.6 0.1 1.9 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_8 PF13621.6 KPA39004.1 - 0.045 13.5 0.3 0.9 9.2 0.0 2.6 1 1 1 2 2 2 0 Cupin-like domain Cupin_1 PF00190.22 KPA39004.1 - 0.091 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 KPA39004.1 - 0.16 11.7 0.1 3.5 7.4 0.0 2.7 3 0 0 3 3 3 0 Cupin domain AMP-binding PF00501.28 KPA39005.1 - 7.5e-67 225.8 0.0 1.1e-66 225.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA39005.1 - 4.5e-14 53.2 0.1 9.6e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 KPA39006.1 - 5.3e-25 88.2 0.0 8.3e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA39006.1 - 4.6e-14 52.9 0.0 9.9e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA39006.1 - 1.7e-12 47.4 0.0 4.1e-11 42.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA39006.1 - 1.9e-10 41.3 0.0 3.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA39006.1 - 1.3e-08 35.4 0.0 1.1e-07 32.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KPA39006.1 - 6.5e-05 23.1 0.0 9.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KPA39006.1 - 0.0006 19.3 0.8 0.01 15.3 0.0 2.7 3 0 0 3 3 3 1 Putative methyltransferase Ubie_methyltran PF01209.18 KPA39006.1 - 0.00065 19.1 0.0 0.01 15.2 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPA39006.1 - 0.0045 16.6 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KPA39006.1 - 0.0089 15.4 0.0 0.021 14.1 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KPA39006.1 - 0.0099 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KPA39006.1 - 0.028 13.8 0.0 0.04 13.3 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 KPA39006.1 - 0.078 12.3 0.0 0.3 10.4 0.0 1.8 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_8 PF05148.15 KPA39006.1 - 0.09 12.6 0.0 0.29 10.9 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase FAD_binding_4 PF01565.23 KPA39007.1 - 2.5e-25 88.8 0.5 1e-24 86.8 0.7 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KPA39007.1 - 0.094 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Methyltransf_23 PF13489.6 KPA39008.1 - 2e-21 76.5 0.0 2.8e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA39008.1 - 7.7e-16 58.6 0.0 2.7e-15 56.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA39008.1 - 7.5e-13 49.0 0.0 1.6e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA39008.1 - 8.4e-12 45.1 0.0 1.5e-10 41.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA39008.1 - 1.2e-10 42.0 0.0 4.6e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA39008.1 - 5.9e-07 29.1 0.0 3.1e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KPA39008.1 - 5.8e-05 22.6 0.0 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KPA39008.1 - 0.00058 19.3 0.0 0.0011 18.4 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KPA39008.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KPA39008.1 - 0.0032 16.8 0.0 0.011 15.1 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KPA39008.1 - 0.0058 16.4 0.0 0.0091 15.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 KPA39008.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 KPA39008.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain MACPF PF01823.19 KPA39010.1 - 4.2e-06 27.0 0.5 9.9e-06 25.8 0.5 1.6 1 0 0 1 1 1 1 MAC/Perforin domain MFS_1 PF07690.16 KPA39011.1 - 9.2e-17 61.0 45.5 1e-14 54.2 34.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF624 PF04854.14 KPA39011.1 - 0.0046 17.0 2.8 0.0046 17.0 2.8 3.4 5 1 0 5 5 5 1 Protein of unknown function, DUF624 PALP PF00291.25 KPA39012.1 - 4.2e-40 138.0 0.2 5.1e-40 137.7 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SnoaL_3 PF13474.6 KPA39013.1 - 0.0031 17.8 0.0 0.026 14.8 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain Phage_base_V PF04717.12 KPA39013.1 - 0.025 14.5 0.0 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 Type VI secretion system, phage-baseplate injector DUF2397 PF09660.10 KPA39013.1 - 0.19 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Unstab_antitox PF09720.10 KPA39014.1 - 0.068 13.2 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Putative addiction module component SOR_SNZ PF01680.17 KPA39015.1 - 3e-106 353.8 8.3 4.2e-106 353.3 8.3 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KPA39015.1 - 3e-09 36.5 7.6 2.6e-07 30.2 0.4 2.5 2 2 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KPA39015.1 - 0.0002 20.6 0.4 0.41 9.7 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KPA39015.1 - 0.00076 19.0 0.4 0.065 12.7 0.0 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 KPA39015.1 - 0.0015 17.7 0.2 0.045 12.9 0.0 2.4 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 KPA39015.1 - 0.0056 15.9 0.8 0.13 11.5 0.0 2.6 2 2 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 KPA39015.1 - 0.012 15.7 0.0 0.04 14.0 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TMP-TENI PF02581.17 KPA39015.1 - 0.016 14.5 1.0 0.39 10.0 0.2 2.6 2 0 0 2 2 2 0 Thiamine monophosphate synthase NMO PF03060.15 KPA39015.1 - 0.19 11.1 10.4 0.27 10.6 2.8 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase SNO PF01174.19 KPA39016.1 - 1.6e-54 184.6 0.0 9.4e-53 178.8 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KPA39016.1 - 3.5e-09 36.5 0.0 4.5e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KPA39016.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S51 PF03575.17 KPA39016.1 - 0.048 13.3 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 Ank_2 PF12796.7 KPA39017.1 - 2.3e-45 153.1 0.7 2.6e-12 47.2 0.4 5.5 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA39017.1 - 1.5e-38 130.7 0.7 9e-08 32.5 0.0 7.9 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA39017.1 - 5.2e-33 109.4 0.5 0.0019 18.5 0.0 10.0 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 KPA39017.1 - 1.8e-32 110.9 1.9 5.1e-07 29.8 0.0 7.8 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KPA39017.1 - 2.6e-26 90.9 13.0 0.0034 17.8 0.0 10.3 10 0 0 10 10 10 7 Ankyrin repeat Shigella_OspC PF06128.11 KPA39017.1 - 0.0021 17.8 2.7 4.2 7.0 0.0 4.8 2 2 4 6 6 6 1 Shigella flexneri OspC protein DUF4040 PF13244.6 KPA39018.1 - 0.098 12.8 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) WD40 PF00400.32 KPA39019.1 - 1.1e-48 162.1 20.7 2e-09 37.9 1.2 9.0 8 2 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA39019.1 - 6e-12 45.7 0.2 0.00015 22.0 0.0 4.7 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA39019.1 - 4.8e-05 22.2 3.8 0.0074 15.0 0.1 3.8 5 1 1 6 6 6 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KPA39019.1 - 0.00061 18.6 0.0 0.84 8.3 0.0 2.6 3 0 0 3 3 3 2 Nup133 N terminal like Cytochrom_C_2 PF01322.20 KPA39019.1 - 0.24 12.3 0.6 0.52 11.2 0.6 1.5 1 0 0 1 1 1 0 Cytochrome C' Abhydrolase_1 PF00561.20 KPA39021.1 - 1.2e-13 51.3 0.0 2.8e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA39021.1 - 7.4e-07 28.7 0.0 0.00053 19.3 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA39021.1 - 8.7e-07 29.8 0.0 1.1e-06 29.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KPA39021.1 - 0.0021 16.8 0.0 0.0099 14.6 0.1 1.9 2 1 0 2 2 2 1 Ndr family Sugar_tr PF00083.24 KPA39022.1 - 2.2e-120 402.6 20.2 2.5e-120 402.4 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA39022.1 - 5.5e-22 78.2 43.5 3.9e-16 58.9 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KPA39022.1 - 0.0063 16.7 1.3 0.0063 16.7 1.3 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF2530) PhoQ_Sensor PF08918.10 KPA39023.1 - 0.047 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoQ Sensor PIP5K PF01504.18 KPA39024.1 - 8.3e-42 143.3 0.0 8.3e-40 136.7 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase ThrE PF06738.12 KPA39025.1 - 4.4e-71 239.1 7.8 1e-69 234.6 2.7 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KPA39025.1 - 1.6e-06 28.3 1.2 1.6e-06 28.3 1.2 3.5 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE WD40 PF00400.32 KPA39026.1 - 2e-11 44.2 0.3 2e-10 41.1 0.1 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA39026.1 - 1.6e-05 25.1 0.2 0.00012 22.3 0.0 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KPA39026.1 - 0.021 14.4 0.3 0.097 12.2 0.3 1.9 1 1 0 1 1 1 0 PQQ-like domain Robl_LC7 PF03259.17 KPA39026.1 - 0.074 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain DUF2013 PF09431.10 KPA39027.1 - 8.2e-51 171.8 2.9 8.2e-51 171.8 2.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) LCAT PF02450.15 KPA39028.1 - 4.4e-109 365.2 0.0 5.2e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 KPA39028.1 - 0.2 11.2 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Acetyltransf_1 PF00583.25 KPA39029.1 - 2.5e-18 66.4 0.0 3.1e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA39029.1 - 1e-10 41.7 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA39029.1 - 2.8e-09 36.8 0.1 4e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KPA39029.1 - 4.5e-09 36.6 0.0 6.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KPA39029.1 - 1.6e-06 28.8 0.0 1.9e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KPA39029.1 - 6.8e-06 25.8 0.0 7.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA39029.1 - 6.9e-06 26.2 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA39029.1 - 0.0019 18.3 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_18 PF18014.1 KPA39029.1 - 0.027 14.3 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1917 PF08939.10 KPA39030.1 - 4.3e-88 295.6 0.2 7.8e-88 294.8 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Mhr1 PF12829.7 KPA39030.1 - 0.037 14.1 0.1 0.22 11.6 0.0 2.0 1 1 1 2 2 2 0 Transcriptional regulation of mitochondrial recombination IBN_N PF03810.19 KPA39032.1 - 1.2e-07 31.5 1.0 1.9e-06 27.7 0.1 3.5 5 0 0 5 5 5 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KPA39032.1 - 1.3e-06 28.6 0.2 0.00076 19.6 0.0 3.4 3 0 0 3 3 3 2 Exportin 1-like protein MOR2-PAG1_N PF14222.6 KPA39032.1 - 0.012 14.6 0.1 0.024 13.6 0.1 1.4 1 0 0 1 1 1 0 Cell morphogenesis N-terminal DUF4142 PF13628.6 KPA39032.1 - 0.13 12.5 0.1 8.4 6.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4142) CAT PF00302.18 KPA39032.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase HAD_2 PF13419.6 KPA39033.1 - 6.4e-08 32.9 0.0 1.2e-07 32.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA39033.1 - 0.0021 18.4 0.0 0.0061 16.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 KPA39034.1 - 2e-09 36.7 0.1 7.5e-09 34.9 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA39034.1 - 2e-06 27.8 12.2 5e-06 26.5 12.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec23_trunk PF04811.15 KPA39036.1 - 6.2e-71 238.8 0.0 1e-70 238.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KPA39036.1 - 1.9e-24 85.4 0.1 7.4e-24 83.5 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KPA39036.1 - 2.2e-17 63.6 0.0 4.5e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KPA39036.1 - 4.1e-17 61.9 5.1 7.2e-17 61.1 5.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KPA39036.1 - 3.1e-08 33.4 0.0 8.8e-08 31.9 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KPA39036.1 - 0.039 13.3 0.1 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SLAC1 PF03595.17 KPA39038.1 - 2e-77 260.6 37.1 2.3e-77 260.4 37.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4854 PF16146.5 KPA39039.1 - 0.092 13.1 0.4 0.21 11.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) Ecl1 PF12855.7 KPA39039.1 - 5.8 8.0 9.3 4.5 8.4 0.0 2.2 2 1 0 2 2 2 0 ECL1/2/3 zinc binding proteins NRDD PF13597.6 KPA39040.1 - 1e-165 552.8 0.0 1.2e-165 552.5 0.0 1.1 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Radical_SAM PF04055.21 KPA39040.1 - 4.9e-14 53.1 0.0 1.8e-13 51.2 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 KPA39040.1 - 1.8e-07 31.3 0.1 4.8e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KPA39040.1 - 7.2e-07 29.6 0.1 2.2e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Peptidase_M28 PF04389.17 KPA39041.1 - 1.8e-34 119.2 0.0 2.5e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KPA39041.1 - 4e-15 55.6 0.7 7.1e-15 54.8 0.7 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KPA39041.1 - 1e-05 25.4 0.0 5.8e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KPA39041.1 - 0.088 11.8 0.0 1 8.3 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase DUF3759 PF12585.8 KPA39042.1 - 1.5e-36 124.3 6.3 1.7e-36 124.1 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Glyco_hydro_12 PF01670.16 KPA39043.1 - 1e-11 45.3 5.7 5.5e-10 39.6 5.7 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Chordopox_G2 PF05796.12 KPA39043.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus protein G2 ABC_tran PF00005.27 KPA39045.1 - 9.3e-35 120.1 0.1 2.5e-34 118.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KPA39045.1 - 2.9e-22 79.6 3.9 5.1e-22 78.8 3.9 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KPA39045.1 - 3.1e-07 30.1 0.0 2.2e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KPA39045.1 - 0.00039 20.4 0.0 0.00077 19.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KPA39045.1 - 0.0013 19.2 0.0 0.003 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA39045.1 - 0.0022 18.3 0.0 0.011 16.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KPA39045.1 - 0.0078 15.7 0.1 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KPA39045.1 - 0.0083 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.17 KPA39045.1 - 0.016 15.3 0.1 0.083 13.0 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 KPA39045.1 - 0.024 14.3 0.1 0.051 13.3 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KPA39045.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KPA39045.1 - 0.038 12.9 0.0 0.073 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 KPA39045.1 - 0.08 12.7 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KPA39045.1 - 0.084 13.3 0.0 0.67 10.4 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KPA39045.1 - 0.089 12.8 0.1 0.66 10.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KPA39045.1 - 0.09 12.9 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 KPA39045.1 - 0.096 12.5 0.7 0.69 9.7 0.1 2.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MFS_1 PF07690.16 KPA39046.1 - 9.2e-34 116.9 38.8 1.4e-33 116.3 38.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily 6PGD PF00393.19 KPA39047.1 - 1.5e-57 195.3 0.0 1.9e-57 194.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KPA39047.1 - 2.2e-24 86.4 0.0 8.6e-24 84.5 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KPA39047.1 - 3.2e-05 23.9 0.0 6.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KPA39047.1 - 0.0054 16.4 0.0 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KPA39047.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KPA39047.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CMAS PF02353.20 KPA39047.1 - 0.14 11.4 0.1 0.69 9.1 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase GMC_oxred_C PF05199.13 KPA39048.1 - 3.4e-28 99.0 0.0 5.8e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KPA39048.1 - 1.6e-25 90.1 0.0 8.6e-22 77.9 0.0 3.1 2 1 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 KPA39048.1 - 0.0016 17.8 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA39048.1 - 0.038 14.2 1.4 0.082 13.2 1.4 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KPA39048.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HHH PF00633.23 KPA39048.1 - 0.16 11.9 0.9 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif FAD_binding_2 PF00890.24 KPA39048.1 - 0.19 10.8 3.0 0.28 10.2 3.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KPA39048.1 - 0.28 9.9 0.5 0.42 9.3 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein AltA1 PF16541.5 KPA39049.1 - 5.6e-13 49.7 0.0 1.2e-12 48.7 0.0 1.5 2 0 0 2 2 2 1 Alternaria alternata allergen 1 adh_short PF00106.25 KPA39050.1 - 3.3e-23 82.2 0.0 4.6e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA39050.1 - 9.9e-14 51.5 0.0 1.3e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA39050.1 - 2.7e-05 24.2 0.0 4.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA39050.1 - 0.00019 21.0 0.0 0.0057 16.1 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPA39050.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Spherulin4 PF12138.8 KPA39050.1 - 0.077 12.6 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Spherulation-specific family 4 Fungal_trans_2 PF11951.8 KPA39051.1 - 3.8e-11 42.4 0.8 4.7e-11 42.1 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA39051.1 - 4.1e-09 36.4 6.0 6.7e-09 35.7 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KPA39052.1 - 0.054 13.4 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 F-box-like Pectinesterase PF01095.19 KPA39054.1 - 2e-140 466.7 80.7 5.8e-44 150.0 2.9 7.9 9 1 0 9 9 9 5 Pectinesterase ChW PF07538.11 KPA39054.1 - 1.9 8.5 4.4 14 5.7 0.2 3.8 3 0 0 3 3 3 0 Clostridial hydrophobic W ABC_tran PF00005.27 KPA39055.1 - 1.4e-47 161.7 0.0 1.1e-30 107.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KPA39055.1 - 1.1e-29 104.0 34.6 5.1e-27 95.2 13.4 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KPA39055.1 - 3.5e-05 23.4 0.1 0.013 14.9 0.0 3.4 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KPA39055.1 - 0.0048 17.3 0.3 0.62 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPA39055.1 - 0.011 16.0 0.5 12 6.2 0.1 3.2 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KPA39055.1 - 0.011 15.8 0.2 0.14 12.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 KPA39055.1 - 0.03 14.1 1.2 4.3 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KPA39055.1 - 0.042 13.8 0.1 15 5.5 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 KPA39055.1 - 0.048 14.1 0.1 3 8.3 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KPA39055.1 - 0.1 12.1 0.1 8.6 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 KPA39055.1 - 0.12 11.4 0.1 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.9 KPA39055.1 - 0.13 11.5 0.8 0.63 9.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KPA39055.1 - 0.2 11.3 0.5 11 5.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain TauD PF02668.16 KPA39056.1 - 1.9e-11 44.3 1.8 7.2e-10 39.1 1.6 2.2 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KPA39056.1 - 0.00012 21.3 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 CsiD SUI1 PF01253.22 KPA39057.1 - 1.9e-20 73.1 0.0 4.5e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KPA39057.1 - 0.0005 20.7 0.0 0.002 18.8 0.0 2.0 1 0 0 1 1 1 1 Pre-PUA-like domain Kin17_mid PF10357.9 KPA39057.1 - 0.067 13.1 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein PUA PF01472.20 KPA39057.1 - 0.12 12.4 0.1 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 PUA domain Pheromone PF08015.11 KPA39057.1 - 0.4 11.7 2.8 1.8 9.7 2.8 2.1 1 0 0 1 1 1 0 Fungal mating-type pheromone FAD_binding_4 PF01565.23 KPA39058.1 - 3.5e-21 75.4 0.1 5.6e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPA39058.1 - 0.046 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like Intimin_C PF07979.11 KPA39058.1 - 0.27 11.7 2.0 0.43 11.0 0.1 2.2 2 0 0 2 2 2 0 Intimin C-type lectin domain NPP1 PF05630.11 KPA39060.1 - 6.6e-56 189.5 0.0 7.8e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) SGL PF08450.12 KPA39061.1 - 9.3e-25 87.6 0.2 2.5e-24 86.2 0.1 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KPA39061.1 - 1.3e-06 28.4 0.0 5.2e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KPA39061.1 - 6.6e-06 26.2 0.0 0.00012 22.2 0.0 2.6 2 0 0 2 2 2 1 Arylesterase PD40 PF07676.12 KPA39061.1 - 0.022 14.7 0.1 0.077 13.0 0.1 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat GspH PF12019.8 KPA39061.1 - 0.026 14.9 0.2 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Type II transport protein GspH Pyridoxal_deC PF00282.19 KPA39062.1 - 9.3e-59 199.0 0.0 1.3e-58 198.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 KPA39062.1 - 5.1e-06 25.9 0.0 1.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KPA39062.1 - 1.8e-05 24.2 0.0 0.00012 21.5 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KPA39062.1 - 0.00029 19.9 0.0 0.00056 19.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V LPD29 PF18847.1 KPA39062.1 - 0.0076 17.1 0.0 3.6 8.6 0.0 2.6 2 0 0 2 2 2 2 Large polyvalent protein associated domain 29 adh_short PF00106.25 KPA39063.1 - 0.00015 21.3 0.0 0.00042 19.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA39063.1 - 0.07 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA39064.1 - 0.0024 17.3 0.0 0.003 17.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 KPA39064.1 - 0.094 12.5 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NinD PF17466.2 KPA39065.1 - 0.09 12.9 0.1 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function Coiled-coil_56 PF09813.9 KPA39065.1 - 0.11 12.6 0.9 0.3 11.2 0.1 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 Glyco_hydro_3 PF00933.21 KPA39066.1 - 2.7e-39 135.4 0.0 4e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KPA39066.1 - 1.7e-38 132.6 0.0 4.1e-38 131.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KPA39066.1 - 3.8e-21 75.0 0.1 7.9e-21 73.9 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain HSP20 PF00011.21 KPA39067.1 - 5.3e-13 49.0 0.1 1.5e-08 34.7 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KPA39067.1 - 0.045 13.3 0.0 0.28 10.8 0.0 2.2 1 1 0 1 1 1 0 HSP20-like domain found in ArsA Cyclin_N PF00134.23 KPA39068.1 - 2.5e-28 98.4 0.1 5e-27 94.2 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KPA39068.1 - 1.6e-08 34.7 0.2 5.1e-08 33.0 0.2 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain PMC2NT PF08066.12 KPA39069.1 - 0.013 16.2 1.4 1.3 9.8 0.1 2.1 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF883 PF05957.13 KPA39069.1 - 0.68 10.6 3.9 28 5.4 3.9 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Methyltrn_RNA_3 PF02598.17 KPA39071.1 - 8.3e-103 343.8 0.0 9.4e-103 343.6 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Thioredoxin PF00085.20 KPA39072.1 - 1.5e-25 89.2 0.0 2.1e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin SelK_SelG PF10961.8 KPA39072.1 - 6e-05 23.6 0.2 0.00011 22.8 0.2 1.5 1 0 0 1 1 1 1 Selenoprotein SelK_SelG Thioredoxin_2 PF13098.6 KPA39072.1 - 8.1e-05 23.0 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KPA39072.1 - 0.00093 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KPA39072.1 - 0.001 19.3 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KPA39072.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KPA39072.1 - 0.085 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 KPA39072.1 - 0.089 13.0 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KPA39072.1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Rsm22 PF09243.10 KPA39073.1 - 2e-30 106.0 0.0 1.9e-29 102.8 0.0 2.4 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_12 PF08242.12 KPA39073.1 - 0.098 13.4 0.0 0.25 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S9 PF00326.21 KPA39075.1 - 9.5e-07 28.5 0.3 2.1e-06 27.3 0.2 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KPA39075.1 - 2.1e-05 24.1 0.2 3.8e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KPA39075.1 - 0.0015 18.4 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KPA39075.1 - 0.0041 16.8 0.1 0.014 15.1 0.1 1.7 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.12 KPA39075.1 - 0.099 11.3 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Glyco_hydro_12 PF01670.16 KPA39076.1 - 6.7e-74 248.5 11.1 7.7e-74 248.3 11.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 p450 PF00067.22 KPA39077.1 - 3.1e-53 181.2 0.0 4.5e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GST_N PF02798.20 KPA39078.1 - 1.8e-14 53.8 0.0 3.6e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPA39078.1 - 1.4e-11 44.4 0.0 2.7e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPA39078.1 - 7.6e-08 32.7 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPA39078.1 - 1.8e-07 31.4 0.0 3.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPA39078.1 - 0.00026 21.1 0.0 0.00058 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPA39078.1 - 0.00064 19.7 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CitMHS PF03600.16 KPA39079.1 - 0.00038 19.7 4.9 0.00038 19.7 4.9 1.5 2 0 0 2 2 2 1 Citrate transporter EHN PF06441.12 KPA39080.1 - 3.8e-25 88.4 0.9 6.5e-25 87.6 0.9 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPA39080.1 - 2.2e-06 27.5 0.1 3.6e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA39080.1 - 0.00021 22.0 3.7 0.00043 20.9 3.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Oxysterol_BP PF01237.18 KPA39081.1 - 5.7e-55 186.7 0.3 4.9e-53 180.3 0.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein FTCD_N PF07837.12 KPA39081.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.6 1 1 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain DOPA_dioxygen PF08883.11 KPA39082.1 - 2e-40 137.3 0.0 2.6e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Glycos_transf_2 PF00535.26 KPA39082.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_hydro_53 PF07745.13 KPA39085.1 - 8.3e-98 327.5 0.0 9.4e-98 327.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Dimer_Tnp_hAT PF05699.14 KPA39086.1 - 1.8e-12 46.9 0.1 3.6e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KPA39086.1 - 0.067 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Lumazine_bd_2 PF12893.7 KPA39086.1 - 0.21 12.3 0.3 89 3.8 0.0 3.7 4 0 0 4 4 4 0 Putative lumazine-binding Aa_trans PF01490.18 KPA39087.1 - 7.4e-36 123.7 35.5 8.5e-36 123.5 35.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 KPA39087.1 - 3.8e-08 32.5 11.7 3.8e-08 32.5 11.7 2.1 2 0 0 2 2 2 2 Spore germination protein AA_permease PF00324.21 KPA39087.1 - 1.7e-05 23.7 26.6 1.7e-05 23.7 26.6 2.1 1 1 1 2 2 2 1 Amino acid permease Fungal_trans PF04082.18 KPA39089.1 - 1.6e-13 50.3 0.0 2.5e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.7 KPA39090.1 - 6.6e-15 55.5 0.1 1e-10 42.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KPA39090.1 - 3.1e-12 46.3 1.1 0.0094 16.4 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KPA39090.1 - 4.3e-11 42.8 1.1 0.00011 22.4 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPA39090.1 - 6.3e-11 42.6 0.1 0.0038 17.8 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA39090.1 - 2.6e-10 39.6 0.3 0.024 15.2 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat TPT PF03151.16 KPA39092.1 - 2.6e-09 36.8 13.7 3.1e-09 36.6 13.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Glyco_transf_64 PF09258.10 KPA39093.1 - 4.6e-38 130.9 0.4 6.3e-38 130.5 0.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.6 KPA39093.1 - 0.0067 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NmrA PF05368.13 KPA39094.1 - 3.3e-22 79.2 0.0 4.3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA39094.1 - 2.8e-13 50.2 0.1 5.4e-13 49.2 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KPA39094.1 - 8.1e-05 22.7 0.0 0.0002 21.5 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KPA39094.1 - 0.00011 22.4 0.1 0.00025 21.3 0.1 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KPA39094.1 - 0.0025 18.3 0.1 0.0044 17.4 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KPA39094.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KPA39094.1 - 0.18 11.9 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Tyrosinase PF00264.20 KPA39096.1 - 4.7e-51 174.2 0.2 7.6e-51 173.5 0.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box_2 PF09011.10 KPA39096.1 - 0.011 16.3 0.5 0.026 15.1 0.4 1.7 2 0 0 2 2 2 0 HMG-box domain HMG_box PF00505.19 KPA39096.1 - 0.024 15.0 0.2 0.061 13.7 0.2 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box DUF1100 PF06500.11 KPA39096.1 - 0.038 12.8 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) MAPEG PF01124.18 KPA39097.1 - 5.6e-21 74.8 1.0 6.2e-21 74.6 1.0 1.0 1 0 0 1 1 1 1 MAPEG family Ank_2 PF12796.7 KPA39098.1 - 1.5e-45 153.6 8.2 1.7e-13 50.9 0.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA39098.1 - 1.7e-27 95.4 3.7 3.2e-10 40.3 0.0 4.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA39098.1 - 1.1e-22 77.7 1.9 0.11 13.1 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KPA39098.1 - 1e-18 67.1 6.1 1.4e-06 28.5 0.3 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KPA39098.1 - 1.1e-17 63.6 5.9 0.045 14.2 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat HET PF06985.11 KPA39098.1 - 1.3e-12 48.3 6.6 8.1e-11 42.5 0.9 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_4 PF02056.16 KPA39099.1 - 0.00099 18.7 0.8 0.26 10.8 0.1 2.2 2 0 0 2 2 2 2 Family 4 glycosyl hydrolase p450 PF00067.22 KPA39100.1 - 8.1e-48 163.3 0.0 1.1e-47 162.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KPA39101.1 - 1.3e-44 152.6 0.0 2.5e-44 151.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA39101.1 - 6.6e-40 136.6 0.0 9.7e-40 136.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 KPA39101.1 - 0.00044 19.7 0.0 0.00057 19.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 KPA39101.1 - 0.0021 17.9 0.0 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KPA39101.1 - 0.0078 15.4 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KPA39101.1 - 0.019 14.9 0.0 0.066 13.1 0.0 1.8 2 0 0 2 2 2 0 KR domain Epimerase PF01370.21 KPA39101.1 - 0.021 14.3 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NTP_transf_3 PF12804.7 KPA39101.1 - 0.039 14.3 0.0 0.076 13.4 0.0 1.3 1 1 0 1 1 1 0 MobA-like NTP transferase domain DUF5104 PF17117.5 KPA39101.1 - 0.13 12.7 0.0 0.38 11.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5104) GDP_Man_Dehyd PF16363.5 KPA39101.1 - 0.15 11.4 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pec_lyase_C PF00544.19 KPA39103.1 - 1.6e-17 63.8 4.9 7.8e-16 58.3 4.9 2.2 1 1 0 1 1 1 1 Pectate lyase CBM_1 PF00734.18 KPA39103.1 - 1.3e-11 44.3 4.8 1.3e-11 44.3 4.8 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Beta_helix PF13229.6 KPA39103.1 - 1e-06 28.7 7.8 2.3e-05 24.3 8.1 2.2 1 1 1 2 2 2 2 Right handed beta helix region DUF3551 PF12071.8 KPA39103.1 - 0.63 10.1 0.1 0.63 10.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3551) Sortilin-Vps10 PF15902.5 KPA39104.1 - 6.6e-19 68.0 3.1 3.8e-06 26.0 0.1 4.6 4 1 0 4 4 4 3 Sortilin, neurotensin receptor 3, BNR PF02012.20 KPA39104.1 - 2.4e-11 41.8 31.6 0.13 12.4 0.1 8.9 8 0 0 8 8 8 6 BNR/Asp-box repeat BNR_2 PF13088.6 KPA39104.1 - 2e-07 30.6 5.3 0.19 11.0 0.0 5.9 4 1 2 6 6 6 4 BNR repeat-like domain BNR_6 PF15899.5 KPA39104.1 - 4.7e-05 23.1 13.9 4.3 7.7 0.0 7.2 6 0 0 6 6 6 3 BNR-Asp box repeat Kelch_3 PF13415.6 KPA39104.1 - 0.088 13.1 2.3 0.23 11.8 0.1 3.0 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF1254 PF06863.12 KPA39105.1 - 2.1e-24 86.1 0.2 3.4e-24 85.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 KPA39105.1 - 7.3e-06 26.4 0.0 2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) DUF5011 PF16403.5 KPA39105.1 - 0.22 11.6 0.8 0.47 10.6 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) Cerato-platanin PF07249.12 KPA39106.1 - 7e-49 164.9 2.7 7.8e-49 164.7 2.7 1.0 1 0 0 1 1 1 1 Cerato-platanin SCAN PF02023.17 KPA39107.1 - 0.1 12.4 0.0 0.95 9.3 0.0 2.1 2 0 0 2 2 2 0 SCAN domain Helo_like_N PF17111.5 KPA39108.1 - 6.7e-40 136.7 8.7 7.4e-22 77.8 0.0 3.1 2 1 1 3 3 3 3 Fungal N-terminal domain of STAND proteins DUF1664 PF07889.12 KPA39108.1 - 0.027 14.5 2.5 1.8 8.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KPA39108.1 - 1.7 9.3 5.1 6.3 7.5 0.4 3.3 3 0 0 3 3 3 0 SlyX Toxin_2 PF00451.19 KPA39108.1 - 1.7 9.0 3.5 12 6.3 0.4 2.5 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 DASH_Dad3 PF08656.10 KPA39108.1 - 2.3 8.3 5.7 3.2 7.9 0.4 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad3 bZIP_1 PF00170.21 KPA39109.1 - 2.1e-06 27.7 8.1 4.9e-06 26.6 8.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPA39109.1 - 0.00065 19.7 6.0 0.00065 19.7 6.0 2.0 2 0 0 2 2 2 1 Basic region leucine zipper LURAP PF14854.6 KPA39109.1 - 0.068 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Leucine rich adaptor protein Plant_zn_clust PF10533.9 KPA39110.1 - 0.038 14.0 1.5 0.049 13.6 0.1 1.9 2 0 0 2 2 2 0 Plant zinc cluster domain Pacs-1 PF10254.9 KPA39111.1 - 0.082 11.9 0.1 0.097 11.6 0.1 1.3 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Citrate_synt PF00285.21 KPA39113.1 - 7.7e-122 406.8 0.0 9.7e-122 406.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF5099 PF17025.5 KPA39114.1 - 0.069 13.6 0.1 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5099) Glyco_hydro_18 PF00704.28 KPA39115.1 - 3.5e-75 253.6 0.0 4.3e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KPA39115.1 - 1.3e-05 25.6 19.3 2.9e-05 24.4 19.3 1.6 1 0 0 1 1 1 1 Chitin recognition protein GDP_Man_Dehyd PF16363.5 KPA39116.1 - 1.4e-50 172.5 0.0 1.8e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KPA39116.1 - 4.2e-43 147.5 0.0 5.1e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA39116.1 - 4.3e-14 52.2 0.0 2.6e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPA39116.1 - 5.3e-06 25.8 0.0 0.0078 15.4 0.1 2.3 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KPA39116.1 - 6.7e-06 25.4 0.0 1.7e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KPA39116.1 - 0.00019 21.0 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KPA39116.1 - 0.0002 20.6 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KPA39116.1 - 0.0016 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPA39116.1 - 0.0028 17.6 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPA39116.1 - 0.098 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.18 KPA39116.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aldedh PF00171.22 KPA39117.1 - 3.6e-135 451.1 0.0 4.9e-135 450.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lipase_GDSL PF00657.22 KPA39117.1 - 2.7e-09 37.3 0.2 8.4e-09 35.7 0.1 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KPA39117.1 - 1.6e-06 28.7 0.1 0.00014 22.3 0.1 2.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF2199 PF09965.9 KPA39117.1 - 0.04 14.0 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) Aa_trans PF01490.18 KPA39118.1 - 4.1e-32 111.4 20.9 1.6e-22 79.8 11.7 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF3040 PF11239.8 KPA39118.1 - 1.4 9.3 8.6 17 5.8 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) Sugar_tr PF00083.24 KPA39119.1 - 1.2e-79 268.3 20.1 1.4e-79 268.1 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA39119.1 - 2.2e-18 66.4 29.8 2.7e-15 56.2 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA39119.1 - 0.00011 21.2 12.5 0.00051 19.0 5.3 2.3 2 0 0 2 2 2 2 MFS_1 like family Ribonuclease_3 PF00636.26 KPA39120.1 - 1.8e-44 150.6 0.2 1.5e-20 73.8 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KPA39120.1 - 1.1e-27 96.7 0.0 2e-10 40.9 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KPA39120.1 - 9.8e-20 70.5 0.2 5.5e-19 68.1 0.0 2.5 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.31 KPA39120.1 - 5.3e-17 62.2 0.1 1.4e-16 60.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA39120.1 - 6.7e-15 55.5 0.0 1.7e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPA39120.1 - 4.3e-13 49.4 0.0 8.4e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KPA39120.1 - 0.094 13.0 0.0 0.63 10.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain RdRP PF05183.12 KPA39121.1 - 9.9e-186 618.9 0.0 1.2e-185 618.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Piwi PF02171.17 KPA39122.1 - 1.8e-70 237.6 0.0 3.4e-70 236.7 0.0 1.5 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KPA39122.1 - 7.5e-19 68.7 0.2 1.5e-18 67.7 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KPA39122.1 - 9.9e-15 54.0 0.1 2.4e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KPA39122.1 - 1.8e-10 41.0 0.0 5.1e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KPA39122.1 - 9e-08 32.0 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KPA39122.1 - 0.089 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Mid domain of argonaute adh_short_C2 PF13561.6 KPA39123.1 - 7e-42 143.6 3.2 8.9e-42 143.2 3.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA39123.1 - 8.6e-36 123.2 1.9 1e-35 122.9 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA39123.1 - 1.2e-12 48.2 0.5 1.7e-12 47.7 0.5 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA39123.1 - 0.005 16.0 0.2 0.0068 15.6 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PDZ PF00595.24 KPA39123.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 PDZ domain His_Phos_2 PF00328.22 KPA39124.1 - 0.0029 17.0 0.6 0.14 11.5 0.0 2.7 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Phage_holin_3_6 PF07332.11 KPA39124.1 - 2.2 8.3 6.2 1 9.4 2.2 2.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III MFS_1 PF07690.16 KPA39125.1 - 1.1e-29 103.5 26.5 1.1e-29 103.5 26.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA39125.1 - 2.6e-11 43.0 5.3 2.6e-11 43.0 5.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Arf PF00025.21 KPA39126.1 - 2.2e-09 37.0 0.0 4.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF4307 PF14155.6 KPA39126.1 - 0.037 13.8 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) DUF3453 PF11935.8 KPA39128.1 - 2e-68 230.4 0.0 8.4e-68 228.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Coiled-coil_56 PF09813.9 KPA39129.1 - 1e-05 25.5 0.0 1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Sds3 PF08598.11 KPA39130.1 - 4.7e-15 56.2 9.4 4.7e-15 56.2 9.4 2.5 2 1 0 2 2 2 1 Sds3-like DUF2951 PF11166.8 KPA39130.1 - 0.084 13.1 0.5 0.33 11.2 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) RRM_1 PF00076.22 KPA39131.1 - 3.7e-13 49.1 0.6 1.2e-09 37.8 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tubulin PF00091.25 KPA39132.1 - 1.3e-65 221.3 0.0 1.8e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KPA39132.1 - 2.4e-44 150.5 0.0 3.9e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KPA39132.1 - 5.2e-05 23.0 0.0 8.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain SKG6 PF08693.10 KPA39133.1 - 0.036 13.5 1.1 0.092 12.2 0.1 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF3573 PF12097.8 KPA39133.1 - 0.2 10.4 2.1 0.31 9.8 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Apc15p PF05841.11 KPA39133.1 - 0.27 12.0 4.1 0.49 11.2 4.1 1.4 1 0 0 1 1 1 0 Apc15p protein Sugar_tr PF00083.24 KPA39134.1 - 2e-33 116.0 4.5 1.3e-27 96.8 0.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPA39134.1 - 1.6e-05 24.0 10.7 0.0002 20.4 3.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4064 PF13273.6 KPA39134.1 - 9.2 6.6 8.5 1.1e+02 3.1 8.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4064 PF13273.6 KPA39136.1 - 0.14 12.4 4.7 0.43 10.9 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Hydrophobin PF01185.18 KPA39137.1 - 9.4e-14 51.8 6.1 9.4e-14 51.8 6.1 2.0 2 1 0 2 2 2 1 Fungal hydrophobin AA_permease PF00324.21 KPA39138.1 - 8.6e-109 364.3 27.3 1.2e-108 363.8 27.3 1.2 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 KPA39138.1 - 4.9e-71 239.8 0.0 6e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 KPA39138.1 - 1.1e-24 87.1 31.8 2.5e-24 85.9 31.5 1.7 1 1 0 1 1 1 1 Amino acid permease PSCyt2 PF07583.11 KPA39138.1 - 0.18 11.7 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Carn_acyltransf PF00755.20 KPA39139.1 - 3.1e-92 310.1 0.0 5.8e-92 309.2 0.0 1.4 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 KPA39139.1 - 3e-68 230.1 0.1 5.3e-68 229.3 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KPA39139.1 - 8.3e-49 166.8 0.5 2.2e-48 165.4 0.5 1.8 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KPA39139.1 - 9.4e-46 156.0 0.1 4.4e-45 153.8 0.1 2.3 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KPA39139.1 - 3.3e-44 151.3 0.0 1.2e-43 149.5 0.0 2.0 2 1 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KPA39139.1 - 8.3e-33 112.9 0.2 2.2e-32 111.6 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KPA39139.1 - 1.7e-20 74.4 0.0 1.1e-17 65.4 0.0 3.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KPA39139.1 - 4.4e-18 65.8 0.0 1.2e-17 64.3 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KPA39139.1 - 1.7e-14 53.9 0.0 1.7e-13 50.7 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KPA39139.1 - 1.7e-11 44.7 0.0 6e-11 43.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KPA39139.1 - 8.7e-10 38.4 0.2 8.7e-10 38.4 0.2 2.6 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KPA39139.1 - 1e-09 39.0 0.0 1e-08 35.8 0.0 2.9 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA39139.1 - 1.1e-07 32.4 0.0 1.1e-06 29.2 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA39139.1 - 2.7e-07 30.6 0.0 2e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 KPA39139.1 - 5e-06 26.4 0.1 1.3e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 KPA39139.1 - 8.7e-06 25.6 0.0 5.9e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KPA39139.1 - 2.2e-05 24.7 0.1 6.5e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KPA39139.1 - 3.4e-05 23.3 0.0 7.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PALP PF00291.25 KPA39139.1 - 0.0036 16.7 0.0 3.9 6.8 0.0 3.4 3 0 0 3 3 3 1 Pyridoxal-phosphate dependent enzyme Methyltransf_16 PF10294.9 KPA39139.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase UDPGT PF00201.18 KPA39140.1 - 3.3e-08 32.8 0.0 7.5e-08 31.6 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 KPA39140.1 - 4.5e-05 23.5 0.0 9.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 KPA39140.1 - 0.0001 22.3 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Anoctamin PF04547.12 KPA39141.1 - 2e-104 349.9 4.8 2.7e-104 349.5 4.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Glyco_hydro_61 PF03443.14 KPA39142.1 - 2.1e-52 178.1 0.0 3.3e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAM-associated PF14303.6 KPA39142.1 - 1.1 10.0 7.2 1.5 9.5 7.2 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CBM_14 PF01607.24 KPA39143.1 - 0.0012 18.9 120.3 1.2 9.4 5.8 12.7 1 1 11 12 12 12 7 Chitin binding Peritrophin-A domain Ntox17 PF15524.6 KPA39143.1 - 0.0055 17.0 12.6 0.42 10.9 1.0 4.5 3 1 1 4 4 4 2 Novel toxin 17 Dor1 PF04124.12 KPA39144.1 - 0.0018 17.1 3.5 0.0022 16.8 3.5 1.0 1 0 0 1 1 1 1 Dor1-like family Amidohydro_2 PF04909.14 KPA39145.1 - 2e-07 31.1 0.0 4.4e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Peptidase_M15_4 PF13539.6 KPA39145.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase adh_short_C2 PF13561.6 KPA39146.1 - 1.3e-57 195.1 0.4 1.6e-57 194.8 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA39146.1 - 1.4e-46 158.4 0.0 2e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA39146.1 - 4.6e-13 49.5 0.0 9.2e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA39146.1 - 0.00048 19.3 0.3 0.0013 17.9 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Aa_trans PF01490.18 KPA39147.1 - 2.2e-25 89.3 33.0 2.5e-25 89.0 33.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KPA39147.1 - 4.1e-06 25.9 40.8 7.9e-06 24.9 31.1 3.1 1 1 1 2 2 2 1 Amino acid permease DUF872 PF05915.12 KPA39147.1 - 0.44 10.7 5.8 0.61 10.3 0.6 3.3 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Polysacc_deac_1 PF01522.21 KPA39148.1 - 4.4e-19 68.6 0.0 8.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KPA39148.1 - 3.3e-05 23.6 0.0 0.00012 21.8 0.0 1.8 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KPA39148.1 - 0.22 9.8 0.0 0.28 9.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Amidase PF01425.21 KPA39149.1 - 1.8e-89 300.8 0.0 2.8e-89 300.2 0.0 1.2 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.18 KPA39149.1 - 1.7e-13 50.2 0.2 2.9e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPA39149.1 - 4.8e-07 29.9 15.7 0.00076 19.8 8.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA39149.1 - 0.0015 19.2 12.5 0.037 14.9 6.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPA39149.1 - 0.011 16.2 2.8 0.011 16.2 2.8 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-UBR PF02207.20 KPA39149.1 - 0.19 11.9 3.0 0.42 10.8 3.0 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) ADH_zinc_N PF00107.26 KPA39150.1 - 2.6e-20 72.7 0.3 5.9e-20 71.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA39150.1 - 4.9e-20 71.4 0.0 1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 KPA39150.1 - 0.0031 16.9 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KPA39150.1 - 0.0043 17.6 0.0 0.0094 16.5 0.0 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 KPA39150.1 - 0.18 11.1 0.4 0.27 10.5 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CBM-like PF14683.6 KPA39151.1 - 5.3e-23 81.7 0.6 9.5e-23 80.9 0.6 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KPA39151.1 - 2.7e-19 68.7 0.1 2.7e-19 68.7 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KPA39151.1 - 0.032 14.5 0.1 0.14 12.5 0.1 2.0 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain FixP_N PF14715.6 KPA39153.1 - 3 7.7 9.3 5.2 6.9 9.3 1.3 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP MFS_1 PF07690.16 KPA39154.1 - 8.7e-35 120.3 31.9 3.8e-34 118.2 32.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA39154.1 - 0.15 10.9 15.8 0.023 13.6 10.7 1.9 1 1 1 2 2 2 0 MFS_1 like family Epiglycanin_C PF14654.6 KPA39154.1 - 0.33 11.0 2.8 0.6 10.2 0.3 2.4 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region SUR7 PF06687.12 KPA39155.1 - 0.042 13.5 0.1 0.042 13.5 0.1 2.3 1 1 1 2 2 2 0 SUR7/PalI family 7tm_1 PF00001.21 KPA39155.1 - 0.07 12.4 0.1 0.07 12.4 0.1 2.2 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF4234 PF14018.6 KPA39155.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4234) COX1 PF00115.20 KPA39155.1 - 0.51 9.1 4.3 3.5 6.4 0.8 2.1 2 0 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I DUF202 PF02656.15 KPA39155.1 - 1.8 9.1 5.8 4.6 7.8 0.9 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF202) FAD_binding_3 PF01494.19 KPA39156.1 - 1.9e-15 57.0 0.1 6.2e-09 35.6 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPA39156.1 - 2.5e-05 24.1 0.1 0.00013 21.7 0.1 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA39156.1 - 2.6e-05 24.3 0.0 5.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA39156.1 - 0.00068 18.9 0.0 0.037 13.2 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA39156.1 - 0.0055 17.2 0.1 0.037 14.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA39156.1 - 0.024 13.9 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA39156.1 - 0.029 13.1 0.0 0.077 11.7 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KPA39156.1 - 0.068 13.1 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KPA39156.1 - 0.089 11.8 0.1 0.38 9.7 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPA39156.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KPA39156.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KPA39156.1 - 0.18 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KPA39156.1 - 0.19 11.0 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KPA39157.1 - 2.2e-31 109.4 0.0 2.7e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA39157.1 - 1.1e-07 31.8 0.1 0.007 16.0 0.1 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA39157.1 - 1.4e-06 27.8 0.1 0.00018 20.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA39157.1 - 2e-06 27.2 0.1 0.0036 16.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA39157.1 - 2.4e-06 26.9 0.0 4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KPA39157.1 - 1.8e-05 25.2 0.2 0.014 15.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA39157.1 - 0.00014 22.0 0.2 0.00035 20.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPA39157.1 - 0.0015 17.3 0.1 0.057 12.1 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KPA39157.1 - 0.0036 16.7 0.4 0.065 12.5 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase TrkA_N PF02254.18 KPA39157.1 - 0.0072 16.6 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_2 PF00890.24 KPA39157.1 - 0.0096 15.0 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 KPA39157.1 - 0.062 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 KPA39157.1 - 0.073 12.5 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus SE PF08491.10 KPA39157.1 - 0.11 11.5 0.0 1.8 7.6 0.0 2.5 3 0 0 3 3 3 0 Squalene epoxidase XdhC_C PF13478.6 KPA39157.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Tenui_NCP PF04876.12 KPA39158.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein AAA_12 PF13087.6 KPA39158.1 - 0.042 13.5 0.0 0.054 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain Transp_cyt_pur PF02133.15 KPA39159.1 - 6.7e-26 91.0 42.9 8.6e-26 90.7 42.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TMEM37 PF15108.6 KPA39159.1 - 0.004 17.0 1.5 0.004 17.0 1.5 2.3 2 0 0 2 2 2 1 Voltage-dependent calcium channel gamma-like subunit protein family DUF1294 PF06961.13 KPA39159.1 - 1.8 8.9 5.6 6.6 7.1 1.1 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) GMC_oxred_N PF00732.19 KPA39161.1 - 6.3e-59 199.8 0.0 1.1e-58 198.9 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA39161.1 - 1.1e-31 110.3 0.0 1.9e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPA39161.1 - 1.2e-05 24.6 2.8 0.047 12.8 1.8 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KPA39161.1 - 3.5e-05 23.0 0.4 6.2e-05 22.2 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KPA39161.1 - 8.2e-05 22.3 0.1 0.0041 16.8 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA39161.1 - 0.00015 21.1 0.8 0.01 15.1 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA39161.1 - 0.0021 17.4 3.6 0.084 12.1 2.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA39161.1 - 0.0089 16.2 2.1 0.03 14.5 2.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPA39161.1 - 0.016 14.4 0.2 0.18 11.0 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KPA39161.1 - 0.041 14.4 0.9 9.1 6.9 0.4 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA39161.1 - 0.048 13.6 0.5 0.11 12.4 0.5 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Stomoxyn PF11585.8 KPA39161.1 - 0.41 10.7 1.2 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn HI0933_like PF03486.14 KPA39161.1 - 0.41 9.3 1.8 0.63 8.7 1.1 1.6 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KPA39161.1 - 0.64 9.0 3.2 3.8 6.5 1.8 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Peptidase_S10 PF00450.22 KPA39162.1 - 7.3e-74 249.7 0.0 9.1e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KPA39162.1 - 0.016 14.5 0.0 0.55 9.4 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 KPA39162.1 - 0.2 10.5 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Chromo PF00385.24 KPA39163.1 - 0.00043 20.1 1.4 0.00043 20.1 1.4 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain CCDC-167 PF15188.6 KPA39164.1 - 0.17 12.2 5.4 0.35 11.2 5.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ank_2 PF12796.7 KPA39165.1 - 2.5e-30 104.9 0.8 3.2e-09 37.2 0.1 4.0 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA39165.1 - 1.3e-22 79.8 1.7 8.1e-06 26.3 0.0 6.3 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA39165.1 - 6.5e-18 63.0 5.3 0.12 13.1 0.0 8.5 9 1 1 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 KPA39165.1 - 6.9e-12 45.4 3.0 0.00097 19.4 0.0 6.3 1 1 6 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 KPA39165.1 - 4.2e-09 36.5 0.2 8.1 7.1 0.0 7.1 8 1 0 8 8 8 4 Ankyrin repeat F-box-like PF12937.7 KPA39165.1 - 0.16 11.9 0.2 0.31 11.0 0.2 1.4 1 0 0 1 1 1 0 F-box-like Abhydrolase_6 PF12697.7 KPA39166.1 - 6.3e-16 59.7 0.0 7.4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KPA39166.1 - 3.3e-08 32.7 0.1 8.1e-08 31.5 0.1 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KPA39166.1 - 3.4e-07 29.6 0.0 4e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Ser_hydrolase PF06821.13 KPA39166.1 - 0.00042 20.2 0.0 0.0061 16.4 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Hydrolase_4 PF12146.8 KPA39166.1 - 0.0015 17.9 0.1 0.0024 17.2 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA39166.1 - 0.0026 17.5 0.5 1.6 8.3 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 KPA39166.1 - 0.11 11.0 0.0 0.85 8.1 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF3894 PF13033.6 KPA39166.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) PIF1 PF05970.14 KPA39168.1 - 8.5e-36 123.9 0.0 1.4e-28 100.1 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KPA39168.1 - 9.8e-20 71.1 0.0 2e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KPA39168.1 - 6.7e-12 46.0 0.0 1.6e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KPA39168.1 - 4.9e-05 21.5 0.7 0.0032 15.5 0.0 2.4 2 1 0 3 3 3 1 Helicase Viral_helicase1 PF01443.18 KPA39168.1 - 7.7e-05 22.5 1.4 0.017 14.8 0.4 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KPA39168.1 - 0.00011 22.1 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Helicase NTPase_1 PF03266.15 KPA39168.1 - 0.00029 20.8 0.3 0.054 13.4 0.1 2.4 2 0 0 2 2 2 1 NTPase DEAD PF00270.29 KPA39168.1 - 0.00082 19.2 0.0 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase MeaB PF03308.16 KPA39168.1 - 0.0011 18.1 0.1 0.0018 17.3 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KPA39168.1 - 0.0011 19.3 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA39168.1 - 0.002 18.4 0.1 0.0053 17.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KPA39168.1 - 0.003 18.0 0.0 0.0058 17.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KPA39168.1 - 0.0052 16.6 0.1 0.015 15.1 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 KPA39168.1 - 0.0092 16.0 0.1 0.046 13.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KPA39168.1 - 0.01 16.3 0.0 0.025 15.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KPA39168.1 - 0.014 15.4 0.0 0.079 13.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KPA39168.1 - 0.027 14.9 0.0 0.1 13.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KPA39168.1 - 0.029 13.9 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 KPA39168.1 - 0.029 14.1 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 KPA39168.1 - 0.037 13.0 0.1 0.059 12.3 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 KPA39168.1 - 0.067 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KPA39168.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 KPA39168.1 - 0.087 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 KPA39168.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 KPA39168.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 KPA39168.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase adh_short PF00106.25 KPA39169.1 - 3.4e-39 134.3 0.8 8.8e-39 133.0 0.8 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA39169.1 - 1.1e-26 93.9 0.1 2.3e-26 92.8 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA39169.1 - 3.6e-12 46.6 0.3 5.7e-12 45.9 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA39169.1 - 4.7e-06 26.2 0.5 7.6e-06 25.6 0.5 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPA39169.1 - 8.3e-06 25.8 0.6 1.8e-05 24.7 0.6 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPA39169.1 - 0.00016 21.3 0.4 0.00027 20.6 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KPA39169.1 - 0.00063 20.0 0.1 0.57 10.4 0.1 2.2 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KPA39169.1 - 0.086 12.0 0.5 0.19 10.9 0.5 1.7 1 1 0 1 1 1 0 Male sterility protein Peptidase_M36 PF02128.15 KPA39170.1 - 1.2e-159 531.5 4.6 1.6e-159 531.0 4.6 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KPA39170.1 - 1.8e-19 69.3 2.4 4.2e-19 68.1 2.4 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KPA39170.1 - 0.063 13.1 0.4 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Aldo_ket_red PF00248.21 KPA39171.1 - 8.1e-65 218.9 0.0 9.5e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNP_C_terminal PF17839.1 KPA39171.1 - 0.15 12.8 0.6 2.1 9.1 0.0 2.7 3 0 0 3 3 3 0 C-terminal domain of cyclic nucleotide phosphodiesterase MFS_1 PF07690.16 KPA39172.1 - 4.7e-14 52.1 74.7 1.3e-13 50.6 44.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 KPA39172.1 - 0.028 14.2 0.4 0.028 14.2 0.4 2.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain EthD PF07110.11 KPA39174.1 - 1.8e-22 80.2 0.0 2.5e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KPA39174.1 - 3.2e-06 27.6 0.0 4.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Dpy19 PF10034.9 KPA39174.1 - 0.08 11.1 0.2 0.099 10.8 0.2 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Mito_carr PF00153.27 KPA39175.1 - 1.6e-72 239.5 0.9 8.4e-26 89.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KPA39175.1 - 5.6e-16 58.8 1.6 3.2e-09 37.1 0.1 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KPA39175.1 - 3.1e-15 54.5 4.4 3.1e-06 26.3 0.2 5.8 7 0 0 7 7 7 4 EF hand EF-hand_5 PF13202.6 KPA39175.1 - 6.1e-14 50.8 1.9 1.2e-06 27.7 0.3 3.9 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KPA39175.1 - 7.7e-14 50.4 2.9 4.5e-06 26.2 0.1 6.0 6 0 0 6 6 6 3 EF-hand domain EF-hand_8 PF13833.6 KPA39175.1 - 3e-09 36.6 0.1 0.73 9.7 0.0 4.9 5 0 0 5 5 5 4 EF-hand domain pair FbpA PF05833.11 KPA39175.1 - 0.0075 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Cyclin_N PF00134.23 KPA39176.1 - 1.4e-44 150.9 0.2 4.1e-44 149.4 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KPA39176.1 - 5.2e-34 116.9 0.0 9.2e-34 116.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain GP67 PF17634.2 KPA39176.1 - 0.66 10.4 4.4 1.6 9.2 4.4 1.6 1 0 0 1 1 1 0 Gene product 67 DNA_pol_phi PF04931.13 KPA39176.1 - 4 5.4 5.6 5.8 4.9 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Zn_clus PF00172.18 KPA39177.1 - 0.00085 19.4 12.6 0.0017 18.5 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KPA39177.1 - 0.0091 15.4 0.5 0.04 13.4 0.1 2.2 2 0 0 2 2 2 1 Histone chaperone domain CHZ MFS_1 PF07690.16 KPA39178.1 - 3e-34 118.5 46.2 3e-34 118.5 46.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 KPA39179.1 - 7.4e-09 35.8 0.1 3.9e-08 33.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA39179.1 - 3e-05 24.8 0.0 3.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.8 KPA39179.1 - 0.016 14.8 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Hydrolase_4 PF12146.8 KPA39179.1 - 0.041 13.2 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 COesterase PF00135.28 KPA39179.1 - 0.091 11.6 0.0 0.16 10.8 0.0 1.3 1 1 0 1 1 1 0 Carboxylesterase family Thioesterase PF00975.20 KPA39179.1 - 0.15 12.2 0.2 0.47 10.5 0.1 1.8 1 1 0 1 1 1 0 Thioesterase domain Say1_Mug180 PF10340.9 KPA39179.1 - 0.15 10.9 0.0 0.33 9.8 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase RNA_pol_Rpc4 PF05132.14 KPA39181.1 - 2.1e-32 112.6 0.1 2.1e-32 112.6 0.1 3.9 3 2 1 4 4 4 1 RNA polymerase III RPC4 UreD PF01774.17 KPA39182.1 - 3.7e-75 252.5 0.1 4.3e-75 252.3 0.1 1.0 1 0 0 1 1 1 1 UreD urease accessory protein AvrL567-A PF11529.8 KPA39182.1 - 0.14 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A STAG PF08514.11 KPA39183.1 - 1.9e-30 105.0 1.0 1.9e-30 105.0 1.0 2.3 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.6 KPA39183.1 - 3.7e-05 24.0 0.4 0.25 11.7 0.0 3.8 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.22 KPA39183.1 - 0.0022 18.1 0.3 7.6 7.1 0.2 4.1 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KPA39183.1 - 0.0023 18.0 0.5 0.16 12.0 0.2 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF2937 PF11157.8 KPA39183.1 - 0.13 12.0 0.1 0.33 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) POT1PC PF16686.5 KPA39184.1 - 7.5e-43 146.1 0.0 1.1e-41 142.3 0.0 2.4 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KPA39184.1 - 1.9e-05 24.6 0.0 0.00015 21.6 0.0 2.3 1 1 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 T6SS_VasE PF05936.12 KPA39184.1 - 0.054 12.2 2.2 0.09 11.5 2.2 1.2 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Tautomerase_3 PF14832.6 KPA39185.1 - 6.5e-12 45.8 0.1 1.7e-11 44.5 0.1 1.7 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme adh_short PF00106.25 KPA39186.1 - 8.3e-23 80.9 0.0 1.6e-22 79.9 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA39186.1 - 1.5e-21 77.0 0.0 1.9e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA39186.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPA39186.1 - 0.033 14.1 0.1 0.12 12.2 0.0 1.9 3 0 0 3 3 3 0 NAD(P)H-binding DUF460 PF04312.13 KPA39186.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) SMYLE_N PF18615.1 KPA39187.1 - 2.7 7.5 6.2 0.72 9.3 0.0 2.2 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain AA_permease_2 PF13520.6 KPA39188.1 - 1.9e-49 168.6 51.1 2.6e-49 168.2 51.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA39188.1 - 7.7e-25 87.4 49.0 2e-24 86.0 49.0 1.5 1 1 0 1 1 1 1 Amino acid permease DUF5134 PF17197.4 KPA39188.1 - 0.074 13.0 5.2 0.1 12.5 2.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) MatE PF01554.18 KPA39189.1 - 4.6e-45 153.2 17.2 1.2e-27 96.5 8.4 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KPA39189.1 - 3.5e-06 27.1 6.0 3.5e-06 27.1 6.0 3.3 2 2 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.21 KPA39190.1 - 1e-90 304.0 0.0 1.3e-90 303.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KPA39190.1 - 0.057 13.6 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain Fungal_trans_2 PF11951.8 KPA39191.1 - 1.5e-18 66.8 0.0 1.6e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asparaginase_2 PF01112.18 KPA39192.1 - 6.8e-72 242.1 1.1 8.7e-72 241.7 1.1 1.0 1 0 0 1 1 1 1 Asparaginase Gpi16 PF04113.14 KPA39194.1 - 5.3e-246 817.4 0.0 6.6e-246 817.1 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 KPA39195.1 - 1.7e-73 247.4 1.4 2e-73 247.2 1.4 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.21 KPA39195.1 - 0.031 14.1 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2130 PF09903.9 KPA39195.1 - 0.039 13.2 0.6 0.07 12.4 0.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Golgin_A5 PF09787.9 KPA39195.1 - 0.069 12.6 2.6 0.1 12.1 2.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 T4SS PF07996.11 KPA39195.1 - 0.071 13.5 0.2 0.071 13.5 0.2 1.5 2 0 0 2 2 2 0 Type IV secretion system proteins CDC27 PF09507.10 KPA39196.1 - 0.014 14.8 23.3 0.021 14.3 23.3 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.13 KPA39196.1 - 0.21 11.5 10.7 0.39 10.7 10.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 KPA39196.1 - 6.7 6.6 9.5 9.6 6.1 9.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Hamartin PF04388.12 KPA39196.1 - 8.8 4.9 11.2 11 4.5 11.2 1.1 1 0 0 1 1 1 0 Hamartin protein SANT_DAMP1_like PF16282.5 KPA39197.1 - 0.03 14.5 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 CUE PF02845.16 KPA39197.1 - 0.048 13.4 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 CUE domain Glyco_hydro_61 PF03443.14 KPA39199.1 - 1.4e-63 214.6 0.0 1.9e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Big_3_4 PF13754.6 KPA39199.1 - 0.071 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Serglycin PF04360.12 KPA39199.1 - 0.27 11.2 1.3 0.68 9.9 1.3 1.6 1 1 0 1 1 1 0 Serglycin DUF2456 PF10445.9 KPA39200.1 - 1.8e-18 66.4 0.1 1.9e-17 63.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) OPA3 PF07047.12 KPA39200.1 - 0.022 14.5 0.0 0.051 13.4 0.0 1.4 1 1 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF2852 PF11014.8 KPA39200.1 - 6.6 6.9 5.9 2.9 8.1 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) Ank_2 PF12796.7 KPA39202.1 - 2e-20 73.2 0.0 1.5e-09 38.3 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA39202.1 - 4.7e-10 39.5 0.1 0.0011 19.2 0.0 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA39202.1 - 8.1e-10 38.1 0.1 0.0042 17.5 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KPA39202.1 - 4.4e-09 36.7 0.0 0.00056 20.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KPA39202.1 - 1.7e-07 31.3 0.7 0.015 15.8 0.1 4.4 3 2 1 4 4 4 2 Ankyrin repeat Las1 PF04031.13 KPA39202.1 - 0.15 12.2 0.6 0.31 11.1 0.6 1.5 1 0 0 1 1 1 0 Las1-like 2-Hacid_dh_C PF02826.19 KPA39203.1 - 9.6e-44 148.9 0.0 3.2e-30 104.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.11 KPA39203.1 - 0.028 14.0 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Propionate catabolism activator IlvN PF07991.12 KPA39203.1 - 0.085 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KPA39203.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KPA39203.1 - 0.22 11.6 0.0 0.48 10.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Peptidase_S28 PF05577.12 KPA39204.1 - 2.2e-50 171.7 0.0 3.2e-38 131.7 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 DUF2920 PF11144.8 KPA39204.1 - 0.1 11.7 0.3 0.16 11.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Ammonium_transp PF00909.21 KPA39205.1 - 3.3e-101 338.9 19.9 3.9e-101 338.6 19.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Bac_rhodopsin PF01036.18 KPA39206.1 - 8.3e-60 202.1 12.7 1.1e-59 201.7 12.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3309 PF11752.8 KPA39206.1 - 0.19 11.8 5.7 0.33 11.0 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF3810 PF12725.7 KPA39206.1 - 5.8 6.2 6.1 20 4.4 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Amino_oxidase PF01593.24 KPA39207.1 - 4.6e-24 85.5 0.0 8.8e-20 71.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA39207.1 - 4.3e-14 52.5 0.0 1.1e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA39207.1 - 3.6e-10 40.0 0.0 4.2e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA39207.1 - 5.6e-10 38.9 0.0 6.1e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPA39207.1 - 8.1e-07 28.5 3.1 3.8e-06 26.2 1.9 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KPA39207.1 - 2.6e-06 26.4 0.2 0.0018 17.1 0.6 2.4 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KPA39207.1 - 1.2e-05 24.8 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPA39207.1 - 0.00019 20.7 0.0 0.00032 20.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KPA39207.1 - 0.00027 20.2 1.7 0.00087 18.5 1.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KPA39207.1 - 0.00045 19.6 0.9 0.00067 19.0 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KPA39207.1 - 0.0032 18.0 4.9 0.01 16.4 1.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA39207.1 - 0.0035 16.4 0.4 0.016 14.3 0.3 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KPA39207.1 - 0.0053 16.0 0.5 0.014 14.7 0.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KPA39207.1 - 0.016 15.1 0.7 0.028 14.3 0.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KPA39207.1 - 0.016 15.6 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding MCRA PF06100.11 KPA39207.1 - 0.017 13.9 0.0 1.9 7.2 0.0 2.1 2 0 0 2 2 2 0 MCRA family AlaDh_PNT_C PF01262.21 KPA39207.1 - 0.021 14.2 0.6 0.034 13.4 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KPA39207.1 - 0.03 14.3 0.6 0.063 13.3 0.2 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KPA39207.1 - 0.057 13.0 0.4 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KPA39207.1 - 0.18 12.1 0.1 0.32 11.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 KPA39207.1 - 0.46 9.3 2.7 1.2 7.9 0.8 2.0 2 0 0 2 2 2 0 Tryptophan halogenase SQS_PSY PF00494.19 KPA39208.1 - 6.8e-61 206.1 0.0 9.1e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.15 KPA39209.1 - 1.8e-76 258.2 0.0 2.2e-76 257.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 KPA39210.1 - 8.7e-38 130.7 0.0 1.1e-37 130.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fungal_trans PF04082.18 KPA39211.1 - 4.4e-13 48.9 0.0 8e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHDPS PF00701.22 KPA39212.1 - 1.1e-42 145.8 0.0 1.4e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Peripla_BP_1 PF00532.21 KPA39212.1 - 0.087 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Ecotin PF03974.13 KPA39213.1 - 0.0097 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Ecotin FeThRed_A PF02941.15 KPA39213.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Ferredoxin thioredoxin reductase variable alpha chain DAO PF01266.24 KPA39214.1 - 2.4e-23 83.3 0.0 3.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA39214.1 - 0.00028 21.0 0.0 0.00065 19.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPA39214.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KPA39214.1 - 0.0031 17.9 0.0 0.0055 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KPA39214.1 - 0.035 13.3 0.1 0.51 9.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KPA39214.1 - 0.036 14.3 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 KPA39214.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pro-kuma_activ PF09286.11 KPA39215.1 - 2.2e-33 115.5 0.1 5.7e-33 114.2 0.1 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KPA39215.1 - 0.011 15.0 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Subtilase family Aldedh PF00171.22 KPA39216.1 - 4.4e-96 322.2 0.0 5.4e-96 321.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3311 PF11755.8 KPA39217.1 - 0.03 14.2 0.6 0.09 12.7 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) P5CR_dimer PF14748.6 KPA39218.1 - 2.4e-29 101.6 0.6 4.4e-29 100.8 0.6 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KPA39218.1 - 5.6e-13 49.3 0.0 1.1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GST_N PF02798.20 KPA39219.1 - 1.6e-12 47.6 0.0 2.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPA39219.1 - 1e-08 35.1 0.0 1.6e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA39219.1 - 1.6e-08 34.7 0.0 2.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPA39219.1 - 1.9e-08 34.5 0.0 4.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPA39219.1 - 2.1e-08 34.3 0.0 3.2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPA39219.1 - 3.4e-07 30.6 0.0 5.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NUDIX PF00293.28 KPA39220.1 - 0.02 14.9 0.1 0.024 14.7 0.1 1.1 1 0 0 1 1 1 0 NUDIX domain Fasciclin PF02469.22 KPA39222.1 - 2.5e-16 60.0 0.1 5.5e-14 52.5 0.0 3.0 2 1 0 2 2 2 2 Fasciclin domain Glyco_hydro_32N PF00251.20 KPA39223.1 - 5.3e-78 262.7 2.4 6.6e-78 262.4 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KPA39223.1 - 0.00011 22.3 0.4 0.00017 21.6 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Peroxidase_2 PF01328.17 KPA39225.1 - 3.9e-58 197.1 0.0 4.9e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Cutinase PF01083.22 KPA39226.1 - 1.3e-49 168.6 0.3 1.5e-49 168.3 0.3 1.0 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 KPA39226.1 - 0.00051 19.7 0.0 0.00069 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) VirJ PF06057.11 KPA39226.1 - 0.0069 16.3 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_3 PF07859.13 KPA39226.1 - 0.0085 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KPA39226.1 - 0.051 13.2 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 KPA39226.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.3 1 1 0 1 1 1 0 PE-PPE domain FSH1 PF03959.13 KPA39226.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) TRI12 PF06609.13 KPA39227.1 - 2.1e-57 194.9 21.9 2.8e-57 194.5 21.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPA39227.1 - 6.6e-22 77.9 49.8 1.6e-21 76.6 45.4 3.3 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA39227.1 - 2e-09 36.9 16.9 2e-09 36.9 16.9 4.4 3 2 2 5 5 5 2 Sugar (and other) transporter DUF3671 PF12420.8 KPA39227.1 - 0.039 14.0 5.6 2.8 8.1 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function p450 PF00067.22 KPA39228.1 - 1.4e-49 169.1 0.0 1.8e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ERG4_ERG24 PF01222.17 KPA39229.1 - 2.2e-142 474.9 2.1 2.8e-142 474.5 2.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ank_4 PF13637.6 KPA39229.1 - 7.4e-23 80.6 0.1 6.2e-05 23.5 0.0 6.0 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA39229.1 - 7.7e-21 74.5 0.0 7e-10 39.4 0.0 3.7 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA39229.1 - 7.8e-18 64.3 0.0 4.6e-08 33.2 0.0 5.2 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA39229.1 - 1.9e-16 58.5 0.1 0.0013 19.1 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KPA39229.1 - 7e-15 54.7 0.0 0.01 16.2 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat DUF1295 PF06966.12 KPA39229.1 - 0.013 15.0 0.3 0.051 13.1 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) HgmA PF04209.13 KPA39230.1 - 1.1e-147 492.2 0.1 1.3e-147 491.9 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Candida_ALS PF05792.13 KPA39232.1 - 1.3e-219 710.2 1273.5 6.9e-09 36.1 8.3 74.6 74 0 0 74 74 74 68 Candida agglutinin-like (ALS) PIN_5 PF08745.11 KPA39232.1 - 0.073 12.5 0.0 19 4.6 0.0 4.7 5 1 0 5 5 5 0 PINc domain ribonuclease DUF1573 PF07610.11 KPA39232.1 - 0.42 10.7 46.7 9.5 6.3 0.0 18.6 11 4 14 25 25 25 0 Protein of unknown function (DUF1573) tRNA-synt_1b PF00579.25 KPA39233.1 - 7.1e-09 35.4 0.0 9.2e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PqqD PF05402.12 KPA39233.1 - 0.082 13.2 0.0 0.74 10.2 0.0 2.1 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Hydrolase_4 PF12146.8 KPA39234.1 - 3e-49 167.5 0.0 3.8e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA39234.1 - 5e-12 46.9 0.1 6.3e-12 46.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA39234.1 - 5.5e-12 45.9 0.4 5.4e-11 42.6 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KPA39234.1 - 0.0062 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KPA39234.1 - 0.01 15.3 0.1 0.84 9.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 KPA39234.1 - 0.04 13.6 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative esterase PGAP1 PF07819.13 KPA39234.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Cation_efflux PF01545.21 KPA39235.1 - 1.4e-16 60.9 10.2 1.7e-16 60.5 10.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KPA39235.1 - 2e-11 43.8 0.8 4.3e-11 42.8 0.8 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Glyco_transf_8 PF01501.20 KPA39236.1 - 6.8e-24 84.8 0.9 2e-22 80.0 0.9 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KPA39236.1 - 0.015 14.6 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative zf-rbx1 PF12678.7 KPA39237.1 - 1.5e-10 41.2 4.0 2.6e-10 40.4 4.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KPA39237.1 - 1.3e-08 35.1 4.8 2.5e-08 34.1 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KPA39237.1 - 1.1e-05 25.4 2.1 2.1e-05 24.4 2.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPA39237.1 - 1.5e-05 24.8 1.6 4.2e-05 23.4 1.7 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KPA39237.1 - 2.3e-05 24.1 3.1 4e-05 23.4 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KPA39237.1 - 4e-05 23.6 0.5 7.3e-05 22.7 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KPA39237.1 - 8e-05 22.4 5.7 0.00045 20.0 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KPA39237.1 - 0.00088 18.9 0.5 0.0018 17.8 0.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KPA39237.1 - 0.00096 19.0 2.3 0.00096 19.0 2.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPA39237.1 - 0.0059 16.4 4.3 0.017 15.0 4.4 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KPA39237.1 - 0.13 12.4 1.0 0.28 11.4 1.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KPA39237.1 - 0.29 10.9 1.4 2.8 7.8 1.4 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 KPA39237.1 - 0.63 9.9 3.2 0.31 10.9 0.6 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KPA39237.1 - 1.1 9.5 2.7 4.7 7.5 2.7 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Glyco_hydro_47 PF01532.20 KPA39238.1 - 3.4e-175 583.4 0.0 3.9e-175 583.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 EF-hand_1 PF00036.32 KPA39239.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KPA39239.1 - 3.5e-36 123.5 5.8 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KPA39239.1 - 6.8e-35 118.7 11.4 2.3e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KPA39239.1 - 2.1e-30 102.0 9.5 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KPA39239.1 - 6.5e-26 88.6 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KPA39239.1 - 1.5e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KPA39239.1 - 3.4e-09 36.6 1.9 0.00075 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KPA39239.1 - 5.6e-09 36.3 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KPA39239.1 - 9.9e-07 28.7 0.0 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KPA39239.1 - 5.8e-06 26.3 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KPA39239.1 - 9.1e-05 23.3 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KPA39239.1 - 0.00012 22.0 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KPA39239.1 - 0.00045 20.2 1.8 0.44 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KPA39239.1 - 0.00062 20.1 0.8 0.66 10.3 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 KPA39239.1 - 0.0014 19.3 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 KPA39239.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 KPA39239.1 - 0.006 15.2 0.0 0.0062 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KPA39239.1 - 0.0091 15.9 0.9 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 KPA39239.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 KPA39239.1 - 0.023 14.9 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 KPA39239.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 KPA39239.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 KPA39239.1 - 0.061 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 KPA39239.1 - 0.066 12.4 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5132 PF17195.4 KPA39239.1 - 0.15 12.2 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RloB PF13707.6 KPA39239.1 - 0.16 12.2 1.1 0.76 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein SNARE PF05739.19 KPA39240.1 - 3.7e-16 58.9 1.2 7.6e-16 57.8 1.2 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KPA39240.1 - 1.9e-05 24.4 10.8 0.013 15.2 0.8 2.1 2 0 0 2 2 2 2 Syntaxin Phage_cap_P2 PF05125.12 KPA39240.1 - 0.00057 19.0 0.1 0.0011 18.1 0.1 1.4 1 0 0 1 1 1 1 Phage major capsid protein, P2 family GCP_C_terminal PF04130.13 KPA39240.1 - 0.0072 15.8 0.5 0.015 14.8 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal DUF2207 PF09972.9 KPA39240.1 - 0.01 14.6 0.4 2.9 6.5 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Syntaxin_2 PF14523.6 KPA39240.1 - 0.011 16.1 2.8 0.011 16.1 2.8 2.4 2 1 0 2 2 2 0 Syntaxin-like protein DASH_Dad4 PF08650.10 KPA39240.1 - 0.031 14.3 0.2 0.6 10.1 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 TMPIT PF07851.13 KPA39240.1 - 0.037 13.3 3.0 0.14 11.4 0.7 2.1 2 0 0 2 2 2 0 TMPIT-like protein Rrp44_CSD1 PF17216.3 KPA39240.1 - 0.046 13.4 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 Rrp44-like cold shock domain MCPsignal PF00015.21 KPA39240.1 - 0.075 12.8 9.9 0.19 11.5 0.9 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DNA_repr_REX1B PF14966.6 KPA39240.1 - 0.089 13.5 0.6 0.089 13.5 0.6 2.4 2 1 0 2 2 2 0 DNA repair REX1-B ATG16 PF08614.11 KPA39240.1 - 0.18 12.0 10.1 0.48 10.6 0.3 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CDC37_C PF08564.10 KPA39241.1 - 0.035 14.2 0.1 0.38 10.9 0.0 2.3 2 0 0 2 2 2 0 Cdc37 C terminal domain COX7a PF02238.15 KPA39242.1 - 1.6e-21 76.4 2.0 1.8e-21 76.2 2.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Clathrin_lg_ch PF01086.17 KPA39243.1 - 7.4e-77 258.5 7.7 8.3e-77 258.3 7.7 1.0 1 0 0 1 1 1 1 Clathrin light chain TipAS PF07739.13 KPA39243.1 - 0.13 12.8 4.6 0.24 12.0 4.6 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain DUF4407 PF14362.6 KPA39243.1 - 0.32 10.3 3.7 0.17 11.2 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CTD_bind PF04818.13 KPA39244.1 - 1.5e-17 64.1 0.3 4.8e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. ABC_membrane PF00664.23 KPA39245.1 - 1.7e-48 165.7 9.5 2.3e-48 165.2 9.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KPA39245.1 - 2.6e-33 115.5 0.0 7.3e-33 114.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KPA39245.1 - 4.5e-05 23.0 0.0 0.0016 17.9 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KPA39245.1 - 0.0012 19.1 0.6 0.0085 16.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA39245.1 - 0.012 16.0 1.0 0.037 14.4 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KPA39245.1 - 0.016 15.7 0.1 0.3 11.5 0.1 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KPA39245.1 - 0.039 14.0 0.1 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KPA39245.1 - 0.041 13.6 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KPA39245.1 - 0.05 12.4 0.1 0.14 10.9 0.1 1.8 1 0 0 1 1 1 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 KPA39245.1 - 0.054 13.2 0.0 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KPA39245.1 - 0.063 13.5 1.6 1.2 9.4 1.6 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.6 KPA39245.1 - 0.092 11.7 1.7 0.48 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) COG4 PF08318.12 KPA39246.1 - 9.5e-128 426.0 0.0 1.3e-127 425.5 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein HSCB_C PF07743.13 KPA39246.1 - 0.062 13.8 4.4 1 9.9 0.2 3.4 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain Sua5_yciO_yrdC PF01300.18 KPA39247.1 - 7.1e-54 182.0 0.0 1e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KPA39247.1 - 1.3e-30 106.7 0.0 1.9e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Clat_adaptor_s PF01217.20 KPA39248.1 - 7.9e-17 61.5 1.4 8.9e-16 58.1 1.4 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MCM PF00493.23 KPA39249.1 - 6.2e-101 336.2 0.0 8.8e-101 335.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KPA39249.1 - 4.8e-39 133.1 0.8 8.6e-39 132.3 0.8 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KPA39249.1 - 5.2e-28 97.3 3.8 1.4e-27 95.9 3.8 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KPA39249.1 - 8.5e-19 68.1 0.3 3.1e-18 66.3 0.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KPA39249.1 - 8.3e-06 25.8 0.1 5.7e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KPA39249.1 - 4.3e-05 23.0 0.0 0.0009 18.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KPA39249.1 - 0.0011 18.9 0.0 0.0045 16.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) GGA_N-GAT PF18308.1 KPA39249.1 - 0.1 12.3 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 GGA N-GAT domain Cys_Met_Meta_PP PF01053.20 KPA39250.1 - 6.3e-25 87.5 0.0 9.9e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KPA39250.1 - 3.5e-08 33.0 0.0 1.2e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II VTC PF09359.10 KPA39251.1 - 7.3e-98 327.3 0.3 1.1e-97 326.7 0.0 1.4 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KPA39251.1 - 3.4e-14 53.0 1.8 3.4e-14 53.0 1.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KPA39251.1 - 5.1e-11 43.1 12.5 1.5e-05 25.1 0.1 3.8 3 1 1 4 4 4 3 SPX domain Fe_dep_repress PF01325.19 KPA39251.1 - 0.0016 18.6 0.1 0.0032 17.6 0.1 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 KPA39251.1 - 0.046 13.6 0.5 0.43 10.5 0.2 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Hexokinase_2 PF03727.16 KPA39253.1 - 1.9e-83 279.6 0.0 2.5e-83 279.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KPA39253.1 - 1.9e-71 240.1 0.0 3.5e-71 239.2 0.0 1.4 2 0 0 2 2 2 1 Hexokinase HIG_1_N PF04588.13 KPA39254.1 - 3.7e-06 27.1 1.3 3.7e-06 27.1 1.3 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF4079 PF13301.6 KPA39254.1 - 0.048 13.8 0.1 0.064 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Romo1 PF10247.9 KPA39254.1 - 0.9 10.0 5.3 0.47 10.9 3.0 1.7 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Kelch_1 PF01344.25 KPA39255.1 - 1.1e-41 140.2 18.0 6e-08 32.2 0.4 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KPA39255.1 - 1.2e-40 136.8 14.2 5.5e-07 29.4 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KPA39255.1 - 3.2e-37 126.1 12.3 4e-07 30.2 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KPA39255.1 - 1.3e-34 118.0 18.7 3.4e-06 27.0 0.9 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KPA39255.1 - 1.4e-33 114.0 16.3 8.7e-07 29.0 0.0 6.4 4 1 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KPA39255.1 - 4.6e-32 108.8 15.8 4.3e-07 29.6 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Dus PF01207.17 KPA39256.1 - 1.2e-40 139.6 0.0 1.1e-30 106.9 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KPA39256.1 - 0.0046 16.7 1.8 0.0046 16.7 1.8 2.7 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 KPA39256.1 - 0.0096 15.8 5.3 0.88 9.6 0.2 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KPA39256.1 - 0.026 14.6 6.1 0.59 10.3 0.8 2.7 2 0 0 2 2 2 0 Zinc finger domain Peroxin-13_N PF04088.13 KPA39257.1 - 2.4e-51 173.8 0.1 4.1e-51 173.1 0.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KPA39257.1 - 1.6e-10 40.5 0.0 2.9e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPA39257.1 - 4.5e-07 29.4 0.0 7.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPA39257.1 - 1.2e-05 25.1 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain LigD_N PF13298.6 KPA39258.1 - 1.9e-36 124.6 0.0 3.5e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) WD40 PF00400.32 KPA39259.1 - 3.7e-17 62.4 12.7 0.0011 19.8 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA39259.1 - 3.3e-16 59.4 0.0 1.7e-05 25.0 0.0 5.4 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPA39259.1 - 2e-05 24.5 0.3 0.025 14.5 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KPA39259.1 - 0.019 14.9 2.7 6.7 6.8 0.4 4.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KPA39259.1 - 0.059 12.3 0.1 17 4.2 0.1 3.4 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HIRA_B PF09453.10 KPA39259.1 - 0.16 11.8 3.4 0.27 11.1 1.1 2.6 2 0 0 2 2 2 0 HIRA B motif Peptidase_S8 PF00082.22 KPA39260.1 - 6.8e-07 28.8 0.4 1.4e-06 27.8 0.4 1.5 1 1 0 1 1 1 1 Subtilase family ECR1_N PF14382.6 KPA39260.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Fungal_trans PF04082.18 KPA39262.1 - 4.7e-15 55.3 0.0 9.4e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA39262.1 - 1.4e-08 34.7 12.0 3.4e-08 33.5 12.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3138 PF11336.8 KPA39262.1 - 0.14 10.8 2.0 0.1 11.2 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Chalcone_3 PF16036.5 KPA39262.1 - 0.14 12.3 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Chalcone isomerase-like Phage_Mu_Gam PF07352.12 KPA39262.1 - 0.21 11.5 1.0 0.4 10.6 1.0 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF5320 PF17253.2 KPA39262.1 - 0.25 12.4 0.7 0.53 11.4 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF4140 PF13600.6 KPA39262.1 - 0.26 11.8 2.0 0.57 10.7 2.0 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Csm1_N PF18504.1 KPA39262.1 - 0.77 10.1 3.9 5.1 7.5 4.3 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain Alpha_L_fucos PF01120.17 KPA39263.1 - 8.2e-96 321.5 9.4 1e-95 321.2 9.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 KPA39263.1 - 4.3e-09 36.8 0.1 1.3e-08 35.3 0.0 1.8 2 0 0 2 2 2 1 Alpha-L-fucosidase C-terminal domain p450 PF00067.22 KPA39264.1 - 3.2e-36 125.1 0.0 5.1e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.15 KPA39265.1 - 1.9e-20 72.9 0.0 1.3e-19 70.2 0.0 2.0 2 1 0 2 2 2 1 Transferase family WES_acyltransf PF03007.16 KPA39265.1 - 0.0012 18.7 0.1 0.0022 17.8 0.1 1.3 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Dicty_REP PF05086.12 KPA39265.1 - 0.11 10.4 0.4 0.16 9.9 0.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CBM_4_9 PF02018.17 KPA39267.1 - 2.9e-07 30.8 0.5 6.3e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Carbohydrate binding domain Sugar_tr PF00083.24 KPA39269.1 - 9.5e-104 347.8 18.9 1.1e-103 347.6 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA39269.1 - 8.8e-29 100.5 37.0 1.6e-18 66.7 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5413 PF17434.2 KPA39269.1 - 0.023 15.0 0.2 0.083 13.2 0.2 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5413) Acyl-thio_N PF12590.8 KPA39269.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Acyl-ATP thioesterase OATP PF03137.20 KPA39269.1 - 6.8 4.8 13.6 0.091 11.0 1.7 3.0 3 1 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family NAD_binding_6 PF08030.12 KPA39270.1 - 0.03 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain FAD_oxidored PF12831.7 KPA39271.1 - 1.5e-90 304.7 0.0 1.9e-90 304.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA39271.1 - 7.3e-06 26.1 0.2 2.9e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPA39271.1 - 4e-05 22.9 0.2 9.1e-05 21.7 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA39271.1 - 0.00012 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA39271.1 - 0.00022 20.5 0.6 0.00036 19.7 0.6 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KPA39271.1 - 0.0024 17.5 0.1 0.023 14.3 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA39271.1 - 0.047 12.4 0.6 0.072 11.8 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Lactamase_B_2 PF12706.7 KPA39271.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Thi4 PF01946.17 KPA39271.1 - 0.061 12.6 0.1 0.15 11.2 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KPA39271.1 - 0.1 13.2 0.0 3.1 8.4 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KPA39272.1 - 2.9e-17 62.6 0.2 4.9e-17 61.8 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gpr1_Fun34_YaaH PF01184.19 KPA39273.1 - 1.1e-29 103.6 19.6 1.3e-29 103.3 19.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3270 PF11674.8 KPA39273.1 - 0.47 10.7 10.0 0.043 14.0 4.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3270) Fungal_trans PF04082.18 KPA39274.1 - 3.1e-09 36.3 0.3 4.8e-09 35.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA39274.1 - 1.1e-05 25.5 15.7 1.8e-05 24.7 15.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain nsp8 PF08717.10 KPA39274.1 - 0.09 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 nsp8 replicase Pro_CA PF00484.19 KPA39275.1 - 8e-12 45.7 0.3 2.1e-10 41.1 0.3 2.1 1 1 0 2 2 2 2 Carbonic anhydrase zf-C2H2 PF00096.26 KPA39276.1 - 1.7e-08 34.4 12.6 0.025 15.0 0.1 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA39276.1 - 2.4e-08 34.1 11.2 0.013 16.3 0.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPA39276.1 - 1.8e-06 28.1 3.3 0.0032 17.8 0.1 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KPA39276.1 - 0.00016 21.6 1.9 0.94 9.5 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-dskA_traR PF01258.17 KPA39276.1 - 0.02 14.9 0.8 0.9 9.5 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Zn-ribbon_8 PF09723.10 KPA39276.1 - 0.068 13.3 0.7 0.068 13.3 0.7 2.5 2 1 1 3 3 3 0 Zinc ribbon domain DZR PF12773.7 KPA39276.1 - 0.13 12.3 0.3 0.13 12.3 0.3 1.9 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2_jaz PF12171.8 KPA39276.1 - 0.14 12.5 1.1 31 5.0 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KPA39276.1 - 0.17 12.2 2.4 0.5 10.7 1.9 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KPA39276.1 - 0.24 11.3 8.7 0.98 9.4 0.2 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KPA39276.1 - 0.24 11.0 2.8 4 7.1 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 KPA39276.1 - 3.2 7.8 8.6 0.91 9.6 0.3 3.0 2 2 0 2 2 2 0 Adenylate kinase, active site lid PAS_9 PF13426.7 KPA39277.1 - 2.5e-13 50.1 0.0 9.7e-13 48.3 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KPA39277.1 - 0.093 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 PAS fold DUF1387 PF07139.11 KPA39277.1 - 0.3 10.8 5.3 17 5.0 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Zip PF02535.22 KPA39277.1 - 2.8 7.1 5.5 4.6 6.4 5.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 KPA39277.1 - 3.1 7.1 19.2 6.4 6.1 19.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Lin-8 PF03353.15 KPA39277.1 - 3.7 7.0 8.5 6.4 6.3 8.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4551 PF15087.6 KPA39277.1 - 3.7 6.3 7.0 5.7 5.7 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) peroxidase PF00141.23 KPA39278.1 - 7.8e-83 277.7 0.0 2.2e-44 151.9 0.0 2.5 2 1 0 2 2 2 2 Peroxidase PBP PF01161.20 KPA39279.1 - 2.8e-16 60.1 0.0 3.3e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_S8 PF00082.22 KPA39280.1 - 5.1e-32 111.3 13.6 1.3e-31 110.0 13.6 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KPA39280.1 - 3.7e-12 46.7 0.7 2e-11 44.4 0.7 2.2 1 1 0 1 1 1 1 Peptidase inhibitor I9 Pectate_lyase PF03211.13 KPA39281.1 - 4.1e-85 284.4 9.6 4.8e-85 284.2 9.6 1.0 1 0 0 1 1 1 1 Pectate lyase Sugar_tr PF00083.24 KPA39282.1 - 1.4e-133 446.1 22.7 1.6e-133 445.9 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA39282.1 - 2.5e-24 85.9 29.1 3.8e-20 72.1 22.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AF-4 PF05110.13 KPA39283.1 - 0.0057 14.8 0.1 0.0063 14.7 0.1 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Amino_oxidase PF01593.24 KPA39284.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Chromo PF00385.24 KPA39285.1 - 1.4e-07 31.3 2.9 0.00025 20.9 0.2 2.8 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KPA39285.1 - 0.087 12.9 0.0 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 Chromo shadow domain BAH PF01426.18 KPA39287.1 - 0.0034 17.2 0.0 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KPA39287.1 - 0.0036 17.5 1.9 0.0051 17.0 0.4 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD PF00628.29 KPA39287.1 - 0.01 15.7 3.6 0.01 15.7 3.6 1.9 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KPA39287.1 - 0.026 14.7 1.8 0.034 14.3 0.6 1.8 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 KPA39287.1 - 1.7 9.0 5.8 0.18 12.2 0.8 1.9 2 0 0 2 2 2 0 RING-like domain SPAN-X PF07458.12 KPA39287.1 - 3.4 8.2 6.0 0.57 10.7 0.2 2.6 3 1 1 4 4 4 0 Sperm protein associated with nucleus, mapped to X chromosome FMO-like PF00743.19 KPA39288.1 - 1.8e-15 56.4 0.0 1.3e-12 46.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPA39288.1 - 5.4e-05 22.6 0.0 0.00023 20.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA39288.1 - 0.00051 20.1 0.0 0.0051 16.8 0.0 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPA39288.1 - 0.0024 18.0 0.0 0.0054 16.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPA39288.1 - 0.0024 17.0 0.0 0.019 14.1 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KPA39288.1 - 0.014 15.0 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA39288.1 - 0.063 12.5 0.0 0.16 11.2 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_4 PF07993.12 KPA39289.1 - 9.3e-60 201.9 0.0 1.2e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KPA39289.1 - 5.2e-09 35.9 0.0 1.8e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA39289.1 - 1.4e-07 30.8 1.4 9.3e-06 24.8 1.4 2.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KPA39289.1 - 0.00075 18.7 1.2 0.0026 17.0 0.7 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KPA39289.1 - 0.015 15.2 0.3 0.074 13.0 0.1 2.1 2 0 0 2 2 2 0 KR domain Histone PF00125.24 KPA39290.1 - 1.2e-41 142.2 1.4 1.5e-41 141.8 1.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KPA39290.1 - 0.00047 20.2 0.0 0.0008 19.5 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KPA39290.1 - 0.001 19.4 0.1 0.0022 18.3 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KPA39290.1 - 0.033 14.5 0.3 0.052 13.8 0.3 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NAD_binding_8 PF13450.6 KPA39291.1 - 5.1e-10 39.4 0.0 9.1e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPA39291.1 - 9.1e-08 31.9 0.4 1.4e-07 31.2 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KPA39291.1 - 3e-07 30.1 0.0 0.00019 20.8 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KPA39291.1 - 6.9e-07 28.7 4.1 1.8e-06 27.4 2.7 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KPA39291.1 - 1.2e-06 27.9 0.4 2.2e-05 23.8 0.2 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KPA39291.1 - 2e-06 26.8 2.3 3.7e-06 25.9 2.3 1.4 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KPA39291.1 - 5.1e-06 26.3 0.1 1e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA39291.1 - 1.5e-05 24.4 0.6 2.8e-05 23.5 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA39291.1 - 2e-05 25.0 0.1 0.0001 22.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA39291.1 - 2.9e-05 23.3 0.1 4.3e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KPA39291.1 - 3.9e-05 23.1 0.0 6.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA39291.1 - 5.9e-05 22.4 0.4 0.0001 21.7 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 KPA39291.1 - 0.0073 15.9 1.1 0.017 14.7 0.8 1.7 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 KPA39291.1 - 0.017 14.4 0.2 0.029 13.7 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KPA39291.1 - 0.055 12.3 0.6 0.084 11.7 0.6 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.6 KPA39291.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AT_hook PF02178.19 KPA39292.1 - 3.3 7.9 8.9 24 5.3 0.1 2.7 2 0 0 2 2 2 0 AT hook motif B_lectin PF01453.24 KPA39293.1 - 1.5e-11 44.8 1.0 2.4e-07 31.2 0.3 2.0 1 1 1 2 2 2 2 D-mannose binding lectin PQQ_2 PF13360.6 KPA39293.1 - 0.0036 16.9 0.9 0.009 15.6 0.9 1.7 1 1 0 1 1 1 1 PQQ-like domain AnfO_nitrog PF09582.10 KPA39293.1 - 0.023 14.0 0.5 0.37 10.1 0.1 2.2 2 1 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) cobW PF02492.19 KPA39295.1 - 1.6e-48 164.6 5.7 6.8e-37 126.8 0.4 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KPA39295.1 - 1.6e-18 66.4 0.1 1.6e-14 53.6 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 KPA39295.1 - 5.8e-06 25.5 0.2 0.00076 18.5 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 KPA39295.1 - 0.0069 16.4 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KPA39295.1 - 0.011 15.4 0.0 0.038 13.7 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MobB PF03205.14 KPA39295.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 KPA39295.1 - 0.024 15.0 2.1 0.062 13.7 0.4 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KPA39295.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPA39295.1 - 0.085 13.4 0.6 0.49 10.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain RsgA_GTPase PF03193.16 KPA39295.1 - 0.11 12.4 0.5 4.9 7.0 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase Raftlin PF15250.6 KPA39295.1 - 0.27 9.9 5.1 0.47 9.1 5.1 1.3 1 0 0 1 1 1 0 Raftlin PI3K_1B_p101 PF10486.9 KPA39295.1 - 0.36 8.6 3.9 0.64 7.7 3.9 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Apt1 PF10351.9 KPA39295.1 - 0.49 9.2 3.8 0.75 8.6 3.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Amidohydro_1 PF01979.20 KPA39296.1 - 1.5e-28 100.1 0.0 3.4e-28 99.0 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPA39296.1 - 1.7e-12 47.6 0.4 2.8e-08 33.7 0.1 2.7 2 1 0 2 2 2 2 Amidohydrolase family ICL PF00463.21 KPA39296.1 - 0.015 13.8 0.1 0.023 13.2 0.1 1.2 1 0 0 1 1 1 0 Isocitrate lyase family Med3 PF11593.8 KPA39297.1 - 1.2 8.3 6.1 1.7 7.8 6.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Fungal_trans_2 PF11951.8 KPA39298.1 - 1.8e-43 148.9 0.3 2.9e-43 148.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hexapep PF00132.24 KPA39298.1 - 6.5e-13 47.9 9.5 4.4e-10 38.9 5.6 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KPA39298.1 - 2.5e-11 43.6 0.0 1.2e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep_2 PF14602.6 KPA39298.1 - 5e-10 38.9 9.9 7.6e-07 28.8 5.8 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 KPA39298.1 - 7.7e-06 25.9 13.9 1.5e-05 25.0 13.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.27 KPA39300.1 - 4.5e-07 29.4 0.6 8.1e-07 28.6 0.6 1.4 1 0 0 1 1 1 1 GATA zinc finger N-SET PF11764.8 KPA39300.1 - 0.053 13.6 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N Prim_Zn_Ribbon PF08273.12 KPA39300.1 - 0.11 12.8 2.2 0.17 12.2 2.2 1.3 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase DUF4974 PF16344.5 KPA39300.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) GATA PF00320.27 KPA39301.1 - 2.2e-10 39.9 1.0 3.5e-10 39.3 1.0 1.3 1 0 0 1 1 1 1 GATA zinc finger Prim_Zn_Ribbon PF08273.12 KPA39301.1 - 0.0072 16.6 0.5 0.012 15.9 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase Zn_clus PF00172.18 KPA39302.1 - 0.0035 17.4 2.0 0.0068 16.5 2.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 KPA39302.1 - 0.058 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD VIT1 PF01988.19 KPA39303.1 - 2.9e-68 230.0 1.5 3.4e-68 229.7 1.5 1.0 1 0 0 1 1 1 1 VIT family Orai-1 PF07856.12 KPA39303.1 - 0.084 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF3278 PF11683.8 KPA39303.1 - 0.16 12.1 0.6 0.38 10.8 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) TctB PF07331.11 KPA39303.1 - 0.23 11.7 5.4 0.11 12.7 1.1 2.4 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family GlpM PF06942.12 KPA39303.1 - 1.3 9.5 5.4 4.3 7.8 0.3 3.1 3 1 0 3 3 3 0 GlpM protein AMP-binding PF00501.28 KPA39304.1 - 5.9e-66 222.8 0.0 4.2e-64 216.7 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KPA39304.1 - 4e-14 53.3 0.2 1.2e-13 51.8 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain bZIP_1 PF00170.21 KPA39305.1 - 1.4e-05 25.0 3.7 1.4e-05 25.0 3.7 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KPA39305.1 - 0.00043 20.3 5.0 0.00043 20.3 5.0 1.6 2 0 0 2 2 2 1 Basic region leucine zipper Swi5 PF07061.11 KPA39305.1 - 0.052 13.6 0.2 0.17 12.0 0.2 1.8 1 0 0 1 1 1 0 Swi5 Zn_clus PF00172.18 KPA39306.1 - 5.1e-11 42.5 11.5 8.2e-11 41.8 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_N2 PF16164.5 KPA39306.1 - 0.63 10.2 4.6 0.52 10.5 1.4 2.1 2 0 0 2 2 2 0 VWA N-terminal BRF1 PF07741.13 KPA39307.1 - 0.032 14.6 1.9 0.042 14.2 1.9 1.3 1 1 0 1 1 1 0 Brf1-like TBP-binding domain Peptidase_A17 PF05380.13 KPA39307.1 - 0.05 13.6 0.1 0.061 13.3 0.1 1.0 1 0 0 1 1 1 0 Pao retrotransposon peptidase PRKCSH-like PF12999.7 KPA39309.1 - 1e-43 149.2 5.5 2.8e-26 92.4 2.4 2.5 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KPA39309.1 - 4.8e-31 107.5 0.3 4.8e-31 107.5 0.3 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KPA39309.1 - 4.4e-10 40.4 0.8 4.4e-10 40.4 0.8 2.2 2 1 0 2 2 1 1 Glucosidase II beta subunit-like protein Osmo_CC PF08946.10 KPA39309.1 - 9.4e-05 22.6 1.7 9.4e-05 22.6 1.7 2.4 1 1 1 2 2 2 1 Osmosensory transporter coiled coil CASP_C PF08172.12 KPA39309.1 - 0.00055 19.4 2.6 0.00098 18.5 2.6 1.3 1 0 0 1 1 1 1 CASP C terminal ATG27 PF09451.10 KPA39309.1 - 0.0019 18.1 0.7 0.0041 17.0 0.7 1.5 1 0 0 1 1 1 1 Autophagy-related protein 27 GTP-bdg_M PF16360.5 KPA39309.1 - 0.019 15.5 2.4 0.019 15.5 2.4 2.9 2 1 0 3 3 3 0 GTP-binding GTPase Middle Region DUF5082 PF16888.5 KPA39309.1 - 0.1 12.9 6.2 26 5.1 3.4 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) RestrictionSfiI PF11487.8 KPA39309.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Type II restriction enzyme SfiI DUF4407 PF14362.6 KPA39309.1 - 0.18 11.2 12.0 0.043 13.2 7.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CCCAP PF15964.5 KPA39309.1 - 0.2 9.9 9.2 0.34 9.2 9.2 1.2 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family Tektin PF03148.14 KPA39309.1 - 0.31 9.8 16.4 2.5 6.8 8.2 3.0 3 0 0 3 3 3 0 Tektin family YlqD PF11068.8 KPA39309.1 - 0.32 11.4 6.3 0.82 10.1 6.3 1.6 1 0 0 1 1 1 0 YlqD protein GAS PF13851.6 KPA39309.1 - 0.36 10.1 16.3 12 5.2 13.6 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KPA39309.1 - 0.38 10.9 6.1 1.8 8.8 0.1 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.13 KPA39309.1 - 0.39 10.3 6.0 8.2 6.0 2.0 2.5 2 0 0 2 2 2 0 fzo-like conserved region AAA_13 PF13166.6 KPA39309.1 - 0.61 8.7 8.4 1 7.9 8.4 1.2 1 0 0 1 1 1 0 AAA domain Mod_r PF07200.13 KPA39309.1 - 1.3 9.1 10.3 27 4.8 8.4 3.0 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Apolipoprotein PF01442.18 KPA39309.1 - 1.5 8.7 15.0 0.049 13.5 8.2 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 KPA39309.1 - 1.8 8.6 5.4 45 4.1 3.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HAUS6_N PF14661.6 KPA39309.1 - 2.1 7.9 7.4 2.2 7.8 5.8 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Filament PF00038.21 KPA39309.1 - 2.4 7.6 17.8 1.8 8.1 0.1 2.5 3 0 0 3 3 3 0 Intermediate filament protein GCIP PF13324.6 KPA39310.1 - 6.1e-19 68.7 2.1 7.8e-19 68.3 0.2 1.9 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Nrap_D6 PF17407.2 KPA39310.1 - 0.0028 17.9 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 BSP_II PF05432.11 KPA39310.1 - 0.0057 16.4 0.8 0.011 15.5 0.8 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) SesA PF17107.5 KPA39310.1 - 0.029 14.6 4.5 3.3 7.9 0.3 3.2 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Med8 PF10232.9 KPA39310.1 - 0.37 10.4 4.5 2.7 7.5 0.5 2.2 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 RRN3 PF05327.11 KPA39310.1 - 1.8 7.0 8.8 4 5.9 4.6 2.7 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 zf-C3HC4_3 PF13920.6 KPA39311.1 - 0.84 9.5 8.8 1 9.3 4.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UFD1 PF03152.14 KPA39312.1 - 1.2e-31 109.5 0.0 9.2e-17 61.1 0.0 3.2 1 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KPA39312.1 - 6.8e-08 32.6 0.3 5.6e-07 29.7 0.0 2.6 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A HIPIP PF01355.17 KPA39312.1 - 0.18 12.2 5.7 3.8 7.9 0.5 3.3 2 0 0 2 2 2 0 High potential iron-sulfur protein F-box-like PF12937.7 KPA39313.1 - 0.00086 19.1 0.0 0.00086 19.1 0.0 3.1 4 0 0 4 4 4 1 F-box-like Aldo_ket_red PF00248.21 KPA39314.1 - 1.4e-56 191.9 0.0 1.7e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MCLC PF05934.11 KPA39315.1 - 0.87 8.2 0.0 0.87 8.2 0.0 2.1 2 0 0 2 2 2 0 Mid-1-related chloride channel (MCLC) Beta-lactamase PF00144.24 KPA39316.1 - 3.4e-31 108.7 0.1 6.8e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase FAT PF02259.23 KPA39317.1 - 4.2e-136 453.7 7.8 1.1e-135 452.3 7.8 1.8 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 KPA39317.1 - 3.5e-73 244.8 7.4 3e-68 228.8 0.8 5.2 5 1 0 5 5 5 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 KPA39317.1 - 4.2e-73 246.3 0.1 7.6e-73 245.4 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 KPA39317.1 - 9.1e-46 154.3 3.5 1.3e-45 153.8 0.2 3.2 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT PF02985.22 KPA39317.1 - 8.2e-20 69.2 9.1 0.00063 19.8 0.1 11.6 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 KPA39317.1 - 3.2e-15 56.3 10.2 0.00033 21.0 0.1 8.6 8 1 0 8 8 8 3 HEAT repeats FATC PF02260.20 KPA39317.1 - 5.2e-13 48.6 0.2 1.8e-12 46.8 0.2 2.0 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 KPA39317.1 - 1e-12 48.3 3.9 0.00027 21.3 0.1 9.2 6 3 3 9 9 9 2 HEAT-like repeat Cnd1 PF12717.7 KPA39317.1 - 9.9e-10 38.7 1.2 0.0065 16.5 0.0 6.7 5 1 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KPA39317.1 - 6.4e-08 33.1 0.4 2.5 8.7 0.0 7.5 6 2 2 8 8 8 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KPA39317.1 - 5.1e-07 28.6 5.4 0.0067 15.0 0.2 5.3 4 1 0 4 4 4 1 Adaptin N terminal region CLASP_N PF12348.8 KPA39317.1 - 0.0021 17.7 10.3 7.5 6.0 0.0 6.9 7 1 1 8 8 8 1 CLASP N terminal Baculo_PEP_C PF04513.12 KPA39317.1 - 0.029 14.4 1.6 0.12 12.4 0.1 2.9 3 0 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus VirDNA-topo-I_N PF09266.10 KPA39317.1 - 0.17 12.1 0.2 0.65 10.2 0.0 2.1 2 0 0 2 2 1 0 Viral DNA topoisomerase I, N-terminal Dopey_N PF04118.14 KPA39317.1 - 0.19 10.8 2.6 0.6 9.2 1.1 2.5 2 0 0 2 2 2 0 Dopey, N-terminal Cohesin_HEAT PF12765.7 KPA39317.1 - 0.42 11.0 2.8 52 4.3 0.0 4.9 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion ANAPC3 PF12895.7 KPA39317.1 - 0.46 10.7 6.2 11 6.3 0.0 4.6 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Tti2 PF10521.9 KPA39317.1 - 0.63 9.5 5.2 5 6.6 0.3 3.9 3 2 2 5 5 5 0 Tti2 family Rtf2 PF04641.12 KPA39318.1 - 7.8e-48 163.1 10.0 2.9e-47 161.3 10.0 1.7 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KPA39318.1 - 6.9e-05 22.6 0.4 0.0012 18.6 0.1 2.3 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KPA39318.1 - 7.1e-05 22.6 0.2 0.00017 21.4 0.2 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KPA39318.1 - 0.00032 20.6 0.1 0.00054 19.9 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KPA39318.1 - 0.0024 17.7 0.4 0.0043 16.9 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA39318.1 - 0.0028 17.9 0.1 0.0048 17.2 0.1 1.4 1 0 0 1 1 1 1 Ring finger domain Rad50_zn_hook PF04423.14 KPA39318.1 - 0.0044 16.8 0.6 0.0044 16.8 0.6 2.7 3 0 0 3 3 3 1 Rad50 zinc hook motif zf-RING_UBOX PF13445.6 KPA39318.1 - 0.0044 17.0 0.5 0.0091 16.0 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn-ribbon_8 PF09723.10 KPA39318.1 - 0.0063 16.6 2.1 0.013 15.6 1.3 1.9 2 0 0 2 2 2 1 Zinc ribbon domain UPF0547 PF10571.9 KPA39318.1 - 0.0096 16.0 2.6 0.15 12.2 0.5 2.5 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 zf-C3HC4_3 PF13920.6 KPA39318.1 - 0.016 15.1 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PRTP PF01366.18 KPA39318.1 - 0.043 11.9 3.9 0.056 11.5 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein YhfH PF14149.6 KPA39318.1 - 0.065 13.2 1.1 0.16 12.0 1.1 1.6 1 0 0 1 1 1 0 YhfH-like protein zf-ribbon_3 PF13248.6 KPA39318.1 - 0.12 11.8 0.4 0.39 10.2 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.25 KPA39318.1 - 0.14 12.0 0.3 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPA39318.1 - 0.25 11.1 1.2 0.36 10.6 0.1 1.8 2 0 0 2 2 2 0 RING-like zinc finger FYDLN_acid PF09538.10 KPA39318.1 - 0.42 11.3 10.5 1.7 9.3 10.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) PPL5 PF18168.1 KPA39318.1 - 2.2 7.5 8.9 3.6 6.8 8.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Fungal_trans_2 PF11951.8 KPA39319.1 - 1.1e-08 34.3 1.9 1.9e-08 33.5 1.9 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA39319.1 - 0.1 12.8 2.3 0.16 12.1 2.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.24 KPA39320.1 - 1e-31 110.4 0.0 1.8e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase SARAF PF06682.12 KPA39321.1 - 5.5e-98 328.7 1.5 7e-98 328.3 1.5 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis BRE1 PF08647.11 KPA39322.1 - 1.5e-26 92.3 10.8 1.5e-26 92.3 10.8 6.5 3 2 3 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KPA39322.1 - 8.5e-09 35.1 7.7 1.4e-08 34.5 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPA39322.1 - 1.4e-08 34.4 6.9 2.4e-08 33.7 6.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KPA39322.1 - 6.6e-08 32.3 10.9 1.2e-07 31.5 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA39322.1 - 2.1e-07 30.6 9.2 4.7e-07 29.5 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA39322.1 - 6.6e-07 29.3 5.7 1.3e-06 28.3 5.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPA39322.1 - 3.1e-06 27.0 10.2 5.3e-06 26.3 10.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KPA39322.1 - 5.6e-06 26.6 8.6 9.5e-06 25.8 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain ATG16 PF08614.11 KPA39322.1 - 0.0049 17.1 29.5 0.0049 17.1 29.5 4.6 1 1 4 5 5 3 1 Autophagy protein 16 (ATG16) JIP_LZII PF16471.5 KPA39322.1 - 0.0065 16.6 2.9 0.0065 16.6 2.9 7.0 5 2 1 7 7 7 1 JNK-interacting protein leucine zipper II zf-C3HC4_4 PF15227.6 KPA39322.1 - 0.0088 16.2 6.7 0.018 15.2 6.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF2779 PF11074.8 KPA39322.1 - 0.091 13.2 1.6 0.62 10.5 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) zf-rbx1 PF12678.7 KPA39322.1 - 0.13 12.5 8.5 1.9 8.9 8.5 2.5 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KPA39322.1 - 0.15 11.9 2.1 0.31 10.9 2.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KPA39322.1 - 0.29 11.0 7.1 1.1 9.1 7.3 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 KPA39322.1 - 0.79 9.9 3.7 2.1 8.6 3.7 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE PF01363.21 KPA39322.1 - 2.9 8.1 11.3 20 5.4 11.2 2.2 1 1 1 2 2 2 0 FYVE zinc finger zf-RING_11 PF17123.5 KPA39322.1 - 3.1 7.6 4.3 7.3 6.4 4.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger Myb_DNA-bind_7 PF15963.5 KPA39323.1 - 3.1e-23 81.5 0.1 3.1e-23 81.5 0.1 2.8 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KPA39323.1 - 1.8e-05 24.9 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPA39323.1 - 0.021 15.0 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain EMC3_TMCO1 PF01956.16 KPA39323.1 - 8.5 6.1 5.2 18 5.0 5.2 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like XPC-binding PF09280.11 KPA39324.1 - 3.2e-24 84.4 13.0 6.1e-24 83.5 13.0 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 KPA39324.1 - 3.8e-24 84.2 13.4 2.8e-13 49.5 0.5 2.7 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 KPA39324.1 - 3.8e-21 74.6 0.1 6.8e-21 73.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KPA39324.1 - 4.8e-07 29.5 0.2 8.8e-07 28.7 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KPA39324.1 - 0.0039 17.0 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain MCM_N PF14551.6 KPA39324.1 - 0.0099 16.4 0.4 0.037 14.6 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Clathrin_H_link PF13838.6 KPA39324.1 - 0.029 14.3 2.5 0.15 12.0 0.4 2.8 2 0 0 2 2 2 0 Clathrin-H-link Rad60-SLD_2 PF13881.6 KPA39324.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KPA39324.1 - 0.16 12.3 0.1 0.31 11.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Wzy_C_2 PF11846.8 KPA39325.1 - 0.069 13.1 0.2 0.069 13.1 0.2 1.8 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF2569 PF10754.9 KPA39325.1 - 0.74 10.2 4.9 0.36 11.3 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Pox_A14 PF05767.12 KPA39325.1 - 2.3 8.4 5.2 8.9 6.5 0.2 2.3 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 FAD_binding_7 PF03441.14 KPA39326.1 - 6.8e-77 257.5 0.3 9.6e-77 257.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KPA39326.1 - 1.7e-36 125.7 0.0 4.2e-36 124.4 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase TPR_14 PF13428.6 KPA39327.1 - 3e-05 24.5 2.9 0.35 11.8 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA39327.1 - 0.0005 20.3 0.8 0.0012 19.0 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KPA39327.1 - 0.0055 17.2 2.0 0.022 15.3 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPA39327.1 - 0.078 13.3 1.3 8.8 6.7 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KPA39327.1 - 0.43 10.9 3.9 1.6e+02 2.9 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPA39327.1 - 0.51 10.6 6.2 13 6.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.11 KPA39328.1 - 3.1e-14 53.4 5.2 3.1e-14 53.4 5.2 4.2 2 1 1 3 3 3 1 U3 snoRNA associated ANAPC16 PF17256.2 KPA39328.1 - 0.011 16.1 0.9 0.025 14.9 0.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 16 PH_10 PF15411.6 KPA39329.1 - 4.3e-30 104.5 0.7 8.4e-30 103.6 0.7 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KPA39329.1 - 2.1e-13 50.9 0.0 3.4e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KPA39329.1 - 2.8e-09 37.1 0.1 1.3e-08 34.9 0.1 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KPA39329.1 - 0.0016 18.8 5.8 0.0028 18.0 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KPA39329.1 - 0.0047 16.9 5.7 0.0081 16.1 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KPA39329.1 - 0.026 14.4 4.9 0.048 13.5 4.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KPA39329.1 - 0.026 14.8 2.8 0.059 13.7 2.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KPA39329.1 - 0.073 13.0 5.7 0.15 11.9 5.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KPA39329.1 - 0.076 13.3 4.6 0.14 12.5 4.6 1.4 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 KPA39329.1 - 0.11 12.2 7.0 0.021 14.5 3.3 1.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF1147 PF06615.11 KPA39329.1 - 0.17 11.9 0.5 0.47 10.5 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING_11 PF17123.5 KPA39329.1 - 0.42 10.4 4.1 0.89 9.4 4.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3H2C3 PF17122.5 KPA39329.1 - 1.5 8.9 5.1 3.3 7.8 5.1 1.6 1 0 0 1 1 1 0 Zinc-finger Cpn60_TCP1 PF00118.24 KPA39330.1 - 3.7e-153 510.7 6.8 4.2e-153 510.5 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TetR_C_14 PF17754.1 KPA39330.1 - 0.073 13.0 0.1 12 5.9 0.0 2.5 2 0 0 2 2 2 0 MftR C-terminal domain HMG_box PF00505.19 KPA39331.1 - 1.1e-08 35.4 0.2 3e-08 34.0 0.1 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KPA39331.1 - 4.2e-05 24.1 0.3 0.00013 22.4 0.1 2.0 2 0 0 2 2 2 1 HMG-box domain CCDC106 PF15794.5 KPA39331.1 - 0.013 15.2 0.8 0.013 15.2 0.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF155 PF02582.14 KPA39332.1 - 1e-52 178.8 0.2 1.4e-52 178.3 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3993 PF13158.6 KPA39333.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) LysM PF01476.20 KPA39334.1 - 5.4e-20 71.2 0.5 0.00015 21.7 0.0 6.7 6 0 0 6 6 6 5 LysM domain F-box-like PF12937.7 KPA39336.1 - 6.9e-10 38.7 0.2 1.8e-09 37.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA39336.1 - 3.3e-05 23.6 0.1 9.8e-05 22.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain DUF3425 PF11905.8 KPA39337.1 - 2.4e-17 63.1 0.1 2.4e-17 63.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Spt20 PF12090.8 KPA39337.1 - 0.048 13.3 5.2 0.073 12.7 5.2 1.2 1 0 0 1 1 1 0 Spt20 family ALMT PF11744.8 KPA39337.1 - 0.15 10.8 0.6 0.2 10.4 0.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 KPA39337.1 - 0.85 9.5 11.5 1 9.3 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 KPA39337.1 - 5.3 4.8 4.9 7 4.4 4.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family adh_short PF00106.25 KPA39338.1 - 5.6e-15 55.3 0.0 1.7e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA39338.1 - 4.8e-09 36.1 0.0 7.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA39338.1 - 7.2e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Peptidase_M28 PF04389.17 KPA39339.1 - 3.7e-41 141.0 0.1 5.7e-41 140.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KPA39339.1 - 1.6e-14 53.6 1.0 1.6e-14 53.6 1.0 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KPA39339.1 - 5.2e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 F-box PF00646.33 KPA39340.1 - 0.00017 21.4 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KPA39340.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 KPA39340.1 - 0.24 11.3 2.9 1.3 9.0 0.1 2.7 2 0 0 2 2 2 0 F-box-like SnoaL PF07366.12 KPA39342.1 - 8.1e-26 90.3 0.0 9.4e-26 90.1 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KPA39342.1 - 4.3e-12 46.6 0.0 5.6e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain tRNA-synt_2 PF00152.20 KPA39344.1 - 1.6e-79 267.3 0.0 1.9e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GMC_oxred_N PF00732.19 KPA39345.1 - 0.03 13.7 1.5 0.037 13.4 1.5 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Phage_holin_6_1 PF09682.10 KPA39345.1 - 0.22 12.0 4.7 0.62 10.5 4.6 2.0 1 1 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Glyco_hydro_47 PF01532.20 KPA39347.1 - 1.4e-169 564.8 0.0 1.6e-169 564.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Utp11 PF03998.13 KPA39348.1 - 3.3e-65 220.5 23.0 3.7e-65 220.3 23.0 1.0 1 0 0 1 1 1 1 Utp11 protein GP67 PF17634.2 KPA39348.1 - 0.02 15.3 0.8 0.02 15.3 0.8 2.5 2 0 0 2 2 2 0 Gene product 67 SLATT_5 PF18160.1 KPA39348.1 - 0.14 11.5 0.2 0.14 11.5 0.2 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Lipoprotein_20 PF13942.6 KPA39348.1 - 0.32 10.9 7.5 0.61 10.0 7.5 1.4 1 0 0 1 1 1 0 YfhG lipoprotein WRNPLPNID PF15017.6 KPA39348.1 - 0.38 11.7 0.1 0.38 11.7 0.1 2.8 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box RRN3 PF05327.11 KPA39348.1 - 7 5.1 9.9 8.8 4.7 9.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Herpes_LMP1 PF05297.11 KPA39349.1 - 5.4 6.1 7.0 8.7 5.4 7.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Cmc1 PF08583.10 KPA39350.1 - 2.2e-14 53.2 6.4 5.2e-14 52.0 6.4 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Gpi16 PF04113.14 KPA39350.1 - 0.032 12.7 0.2 0.038 12.4 0.2 1.0 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component CX9C PF16860.5 KPA39350.1 - 0.11 12.5 0.7 0.24 11.4 0.7 1.6 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KPA39350.1 - 0.25 11.5 2.7 5.7 7.2 0.1 2.3 2 0 0 2 2 2 0 CHCH domain DUF3128 PF11326.8 KPA39350.1 - 1.5 9.2 6.2 89 3.6 6.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) 2OG-FeII_Oxy_3 PF13640.6 KPA39351.1 - 2.3e-10 41.2 0.1 4.7e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily VAD1-2 PF15310.6 KPA39351.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Voltage_CLC PF00654.20 KPA39352.1 - 9.5e-90 301.4 22.2 9.5e-90 301.4 22.2 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel Aminotran_3 PF00202.21 KPA39353.1 - 2.8e-119 398.4 0.0 3.3e-119 398.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KPA39353.1 - 0.00016 20.9 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Fungus-induced PF10917.8 KPA39355.1 - 0.0094 16.2 0.2 1.9 8.9 0.1 3.6 3 0 0 3 3 3 1 Fungus-induced protein 7tm_6 PF02949.20 KPA39355.1 - 0.95 8.5 11.5 1.2 8.1 5.2 2.0 1 1 1 2 2 2 0 7tm Odorant receptor DUF5423 PF17461.2 KPA39355.1 - 0.99 8.2 3.0 0.55 9.0 0.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5423) ABC2_membrane_3 PF12698.7 KPA39355.1 - 1.1 8.3 19.7 3 6.9 10.9 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Serpentine_r_xa PF03383.15 KPA39355.1 - 2.8 7.9 9.3 0.93 9.4 5.9 1.8 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa ECH_1 PF00378.20 KPA39356.1 - 7.7e-23 81.1 0.0 1.1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA39356.1 - 1.8e-15 57.3 0.0 2e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RNA_pol_I_A49 PF06870.12 KPA39357.1 - 3.1e-100 335.8 0.8 3.6e-100 335.5 0.8 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Pkinase PF00069.25 KPA39358.1 - 1.6e-54 185.0 0.0 2.1e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA39358.1 - 3.8e-30 105.0 0.0 5.4e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KPA39358.1 - 1.1e-13 51.3 0.1 2.2e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KPA39358.1 - 4.6e-09 36.0 0.1 9.6e-08 31.7 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KPA39358.1 - 9.5e-06 24.6 0.0 2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KPA39358.1 - 0.00027 20.4 0.0 0.00071 19.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 KPA39358.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 KPA39358.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family FERM_M PF00373.18 KPA39359.1 - 0.015 15.7 0.4 0.023 15.1 0.4 1.4 1 0 0 1 1 1 0 FERM central domain DUF3543 PF12063.8 KPA39360.1 - 1.7e-95 319.1 0.6 2.8e-95 318.5 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KPA39360.1 - 2.6e-62 210.6 0.0 4.6e-62 209.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA39360.1 - 1.4e-42 145.8 0.0 5.4e-42 143.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Aminotran_3 PF00202.21 KPA39361.1 - 1.4e-115 386.3 0.0 1.6e-115 386.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KPA39361.1 - 0.0004 19.8 0.0 0.00089 18.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Glyco_transf_22 PF03901.17 KPA39362.1 - 1.3e-78 265.1 23.8 1.7e-78 264.8 23.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LigD_N PF13298.6 KPA39362.1 - 0.0078 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) RhoGAP PF00620.27 KPA39363.1 - 1.1e-37 129.3 0.0 2.1e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF1264 PF06884.11 KPA39366.1 - 8.5e-78 259.8 0.1 1.4e-77 259.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Phage_min_tail PF05939.13 KPA39366.1 - 0.04 14.3 0.1 0.081 13.3 0.1 1.5 1 0 0 1 1 1 0 Phage minor tail protein Med18 PF09637.10 KPA39367.1 - 9.6e-22 78.0 0.0 1.1e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 Med18 protein PNK3P PF08645.11 KPA39368.1 - 5e-56 188.9 0.0 7.7e-56 188.3 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KPA39368.1 - 5.6e-26 91.4 0.0 2.6e-23 82.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KPA39368.1 - 0.00037 19.9 0.0 0.019 14.3 0.0 2.4 1 1 1 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KPA39368.1 - 0.0044 17.6 0.3 0.85 10.2 0.1 3.2 1 1 1 3 3 3 1 AAA domain Rad17 PF03215.15 KPA39368.1 - 0.0079 16.1 0.0 0.11 12.4 0.0 2.4 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 KPA39368.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF3046 PF11248.8 KPA39368.1 - 0.024 15.0 0.3 1.8 9.0 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) AAA_16 PF13191.6 KPA39368.1 - 0.037 14.4 0.0 0.095 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KPA39368.1 - 0.051 13.5 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KPA39368.1 - 0.054 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 KPA39368.1 - 0.055 12.9 0.3 3.3 7.1 0.0 2.2 1 1 1 2 2 2 0 Chromatin associated protein KTI12 DUF3081 PF11280.8 KPA39368.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) AAA_23 PF13476.6 KPA39368.1 - 0.14 12.7 0.1 0.44 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KPA39368.1 - 0.15 12.6 0.0 0.68 10.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA PF00004.29 KPA39368.1 - 0.19 12.1 0.0 0.48 10.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sugar_tr PF00083.24 KPA39369.1 - 1.6e-84 284.4 18.1 1.9e-84 284.1 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA39369.1 - 3.5e-20 72.2 47.5 5.3e-17 61.8 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 KPA39369.1 - 0.12 12.9 0.1 0.24 11.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Chromo PF00385.24 KPA39370.1 - 2.3e-06 27.4 1.6 4.8e-06 26.4 1.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Acetyltransf_1 PF00583.25 KPA39372.1 - 1.2e-08 35.2 0.0 1.9e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA39372.1 - 5.8e-08 33.1 0.0 1.5e-07 31.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA39372.1 - 1.3e-07 31.6 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA39372.1 - 8.2e-05 22.5 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KPA39372.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATP_transf PF09830.9 KPA39374.1 - 2.1e-20 72.6 0.0 3.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase Herpes_TAF50 PF03326.13 KPA39375.1 - 2.6 6.6 7.3 0.56 8.8 3.9 1.5 2 0 0 2 2 2 0 Herpesvirus transcription activation factor (transactivator) Man-6-P_recep PF02157.15 KPA39376.1 - 1.8e-15 56.7 0.0 2.8e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KPA39376.1 - 7.1e-11 42.5 0.0 1.2e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KPA39376.1 - 2e-07 31.1 0.1 2.2e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ERG4_ERG24 PF01222.17 KPA39377.1 - 1.6e-167 557.7 1.3 1.9e-167 557.4 1.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KPA39377.1 - 0.00033 20.3 0.2 0.00096 18.7 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Glyco_hydro_3_C PF01915.22 KPA39378.1 - 3.1e-38 131.8 0.0 1.3e-37 129.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPA39378.1 - 1.1e-34 120.3 0.0 2e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPA39378.1 - 2.2e-19 69.3 0.0 4.5e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 KPA39378.1 - 0.0095 16.2 0.1 0.029 14.6 0.1 1.8 1 0 0 1 1 1 1 CARDB KMP11 PF03037.16 KPA39381.1 - 0.028 15.2 2.8 0.049 14.4 2.8 1.5 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 Peptidase_S49_N PF08496.10 KPA39381.1 - 1.3 9.1 4.6 1.9 8.5 4.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Phosducin PF02114.16 KPA39381.1 - 2.8 6.8 6.7 5.9 5.8 6.7 1.5 1 1 0 1 1 1 0 Phosducin UPF0052 PF01933.18 KPA39383.1 - 2.5e-61 207.5 0.0 3.2e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 ADH_zinc_N PF00107.26 KPA39384.1 - 6e-30 103.9 0.4 9.1e-30 103.3 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA39384.1 - 2.5e-16 61.0 0.0 5e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA39384.1 - 1.5e-08 34.5 0.0 3.9e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KPA39384.1 - 9.3e-05 22.7 0.0 0.00018 21.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ADH_N_2 PF16884.5 KPA39384.1 - 0.039 13.9 0.0 0.082 12.8 0.0 1.6 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase ELFV_dehydrog PF00208.21 KPA39384.1 - 0.044 13.5 0.1 0.28 10.9 0.3 2.0 1 1 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Granulin PF00396.18 KPA39385.1 - 1.7 9.0 17.3 30 5.0 17.3 2.3 1 1 0 1 1 1 0 Granulin Alpha-amylase PF00128.24 KPA39386.1 - 4.4e-30 105.4 0.0 6.5e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KPA39386.1 - 4e-10 39.7 0.0 7.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DUF3459 PF11941.8 KPA39386.1 - 0.0057 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Alpha-amylase_C PF02806.18 KPA39386.1 - 0.011 16.2 0.0 0.041 14.4 0.0 2.0 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Zn_clus PF00172.18 KPA39387.1 - 8.9e-08 32.1 10.1 8.9e-08 32.1 10.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA39387.1 - 1.9e-07 30.4 1.4 3.2e-07 29.7 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain YkyA PF10368.9 KPA39388.1 - 0.023 14.4 0.3 0.043 13.5 0.1 1.5 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein p450 PF00067.22 KPA39389.1 - 8.4e-69 232.5 0.0 1e-68 232.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-HC5HC2H_2 PF13832.6 KPA39390.1 - 0.052 13.7 6.6 0.06 13.5 6.6 1.2 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KPA39390.1 - 0.058 13.7 6.0 0.071 13.4 6.0 1.2 1 0 0 1 1 1 0 PHD-like zinc-binding domain ApoLp-III PF07464.11 KPA39391.1 - 0.051 13.7 3.9 1 9.4 0.1 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) HU-CCDC81_euk_2 PF18289.1 KPA39392.1 - 0.083 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 F-box-like PF12937.7 KPA39393.1 - 0.2 11.6 1.6 0.25 11.3 0.1 1.9 2 0 0 2 2 2 0 F-box-like GMC_oxred_N PF00732.19 KPA39394.1 - 4.1e-64 216.8 0.0 5.2e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA39394.1 - 2.3e-33 115.7 0.0 5.6e-33 114.5 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPA39394.1 - 4e-07 29.5 0.1 0.023 13.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KPA39394.1 - 4.8e-07 29.3 0.1 0.011 15.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA39394.1 - 7.7e-06 25.7 0.6 3.3e-05 23.6 0.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPA39394.1 - 1.8e-05 24.1 0.1 3.7e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KPA39394.1 - 0.00011 22.3 0.1 0.00027 21.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA39394.1 - 0.00017 20.9 0.3 0.073 12.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA39394.1 - 0.00099 18.3 0.1 0.002 17.3 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KPA39394.1 - 0.0034 16.1 0.3 0.17 10.5 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 KPA39394.1 - 0.009 15.2 0.0 3.6 6.6 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPA39394.1 - 0.048 13.6 0.3 0.1 12.6 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding AATase PF07247.12 KPA39395.1 - 3.2e-09 35.9 0.0 3e-06 26.1 0.0 2.6 2 1 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.20 KPA39395.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Condensation domain Abhydrolase_3 PF07859.13 KPA39396.1 - 1.5e-44 152.4 0.0 2e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPA39396.1 - 6.9e-12 45.0 0.0 1.5e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KPA39396.1 - 0.0069 17.0 0.5 0.013 16.1 0.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KPA39396.1 - 0.092 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family MFS_1 PF07690.16 KPA39397.1 - 1.7e-20 73.3 63.5 2.9e-13 49.5 33.9 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily AMP-binding PF00501.28 KPA39398.1 - 1.8e-23 82.8 0.0 3.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KPA39398.1 - 5.8e-09 36.2 0.2 1.7e-08 34.7 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Transferase PF02458.15 KPA39398.1 - 6.2e-07 28.4 0.0 9.1e-05 21.3 0.0 2.4 2 1 0 2 2 2 2 Transferase family DIT1_PvcA PF05141.12 KPA39399.1 - 2.1e-90 302.9 0.0 3e-90 302.5 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein ABC2_membrane PF01061.24 KPA39399.1 - 1.1e-84 283.1 45.2 6.3e-45 153.2 19.1 2.5 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.12 KPA39399.1 - 1.1e-37 127.8 6.7 2.8e-33 113.7 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 KPA39399.1 - 1.5e-25 90.3 0.0 1e-14 55.2 0.0 3.9 2 1 1 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KPA39399.1 - 2.1e-14 53.9 0.0 4.8e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KPA39399.1 - 1.2e-05 24.6 39.9 0.00014 21.1 16.4 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KPA39399.1 - 2.6e-05 24.7 0.3 0.0018 18.6 0.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KPA39399.1 - 0.00015 21.4 0.2 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KPA39399.1 - 0.00046 20.1 0.5 0.005 16.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KPA39399.1 - 0.00066 19.4 0.7 0.14 12.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KPA39399.1 - 0.003 17.4 0.0 3 7.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KPA39399.1 - 0.0035 17.9 0.1 0.053 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KPA39399.1 - 0.0066 15.9 0.0 0.11 11.9 0.0 2.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KPA39399.1 - 0.02 15.1 0.2 0.24 11.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KPA39399.1 - 0.037 14.3 0.6 1.2 9.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain WW_1 PF18507.1 KPA39399.1 - 0.093 12.4 0.0 0.32 10.7 0.0 1.9 1 0 0 1 1 1 0 WW domain MMR_HSR1 PF01926.23 KPA39399.1 - 0.094 12.8 0.6 8.2 6.6 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KPA39399.1 - 0.34 11.3 1.1 3.4 8.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KPA39399.1 - 0.95 9.4 2.6 12 5.8 0.3 2.8 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KPA39399.1 - 3.7 7.1 4.0 1.1 8.8 0.3 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DJ-1_PfpI PF01965.24 KPA39400.1 - 7.1e-20 71.4 0.0 8.7e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family LPD29 PF18847.1 KPA39400.1 - 0.13 13.2 0.0 0.2 12.6 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 29 GATase PF00117.28 KPA39400.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I MFS_1 PF07690.16 KPA39401.1 - 6e-18 64.9 41.1 2.9e-17 62.6 30.2 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA39401.1 - 2.1e-10 40.1 17.0 2.1e-10 40.1 17.0 3.3 2 2 0 2 2 2 1 Sugar (and other) transporter zf-Tim10_DDP PF02953.15 KPA39402.1 - 4.3e-18 64.7 3.3 5.6e-18 64.3 3.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KPA39402.1 - 0.036 13.7 4.0 0.67 9.6 3.4 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2116 PF09889.9 KPA39402.1 - 1.5 8.8 5.3 0.48 10.5 1.8 1.9 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Nup188_C PF18378.1 KPA39403.1 - 2.9e-156 520.0 0.3 7.1e-156 518.7 0.2 1.7 2 0 0 2 2 2 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KPA39403.1 - 5.2e-47 160.4 0.7 2.2e-36 125.2 0.2 2.9 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.21 KPA39404.1 - 8.4e-95 316.7 0.1 1.5e-94 315.9 0.0 1.5 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KPA39404.1 - 2.2e-50 171.1 0.1 1.1e-45 155.8 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KPA39404.1 - 1.1e-47 162.3 0.0 1.7e-46 158.4 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KPA39404.1 - 2.7e-06 27.3 0.2 1e-05 25.4 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KPA39404.1 - 0.00095 19.0 0.7 0.051 13.3 0.1 2.7 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.18 KPA39404.1 - 0.063 12.3 0.3 0.26 10.3 0.1 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Peripla_BP_2 PF01497.18 KPA39404.1 - 0.11 12.0 0.3 0.42 10.1 0.0 2.0 3 0 0 3 3 3 0 Periplasmic binding protein Use1 PF09753.9 KPA39406.1 - 7.5e-10 39.0 0.1 1.7e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Membrane fusion protein Use1 THOC7 PF05615.13 KPA39406.1 - 1.2 9.4 7.8 0.064 13.5 0.8 2.3 2 1 0 2 2 2 0 Tho complex subunit 7 DUF572 PF04502.13 KPA39406.1 - 7 6.2 7.2 12 5.4 7.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) cwf21 PF08312.12 KPA39407.1 - 4.1e-17 62.0 14.6 4.1e-17 62.0 14.6 2.4 2 0 0 2 2 2 1 cwf21 domain GvpG PF05120.12 KPA39407.1 - 0.072 13.1 12.9 0.19 11.8 0.9 2.5 2 1 0 2 2 2 0 Gas vesicle protein G Trans_reg_C PF00486.28 KPA39407.1 - 5.4 7.2 6.5 0.9 9.7 0.2 2.7 3 1 1 4 4 4 0 Transcriptional regulatory protein, C terminal D123 PF07065.14 KPA39408.1 - 6.4e-117 390.1 0.0 7.5e-117 389.9 0.0 1.0 1 0 0 1 1 1 1 D123 DUF3716 PF12511.8 KPA39409.1 - 1.2e-14 54.1 6.5 2e-14 53.3 6.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) G-alpha PF00503.20 KPA39410.1 - 1.1e-124 416.2 2.5 1.3e-124 415.9 2.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KPA39410.1 - 3.7e-15 55.8 2.0 2.8e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KPA39410.1 - 8.5e-05 22.3 0.0 0.00036 20.3 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KPA39410.1 - 0.0019 17.6 2.9 0.11 11.9 0.0 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KPA39410.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KPA39410.1 - 0.024 14.9 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 KPA39410.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 KPA39410.1 - 0.12 11.9 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KPA39410.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KPA39410.1 - 0.13 12.3 0.1 8.8 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF1771 PF08590.10 KPA39411.1 - 1.2e-22 80.0 7.7 2.2e-22 79.2 7.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KPA39411.1 - 2.9e-10 40.3 0.4 6.9e-10 39.1 0.1 1.8 2 0 0 2 2 2 1 Smr domain YbjN PF10722.9 KPA39411.1 - 0.01 15.9 0.1 0.4 10.7 0.0 2.6 3 0 0 3 3 3 0 Putative bacterial sensory transduction regulator DUF4407 PF14362.6 KPA39411.1 - 0.24 10.7 3.0 0.31 10.3 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1949 PF09186.11 KPA39412.1 - 0.0092 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) DUF2818 PF10993.8 KPA39412.1 - 0.21 12.1 5.1 5.2 7.7 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2818) Vma12 PF11712.8 KPA39412.1 - 0.33 11.0 3.8 0.28 11.3 0.8 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase KTI12 PF08433.10 KPA39413.1 - 3.4e-73 246.5 0.0 6.2e-73 245.6 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KPA39413.1 - 0.00018 21.7 0.1 0.00052 20.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPA39413.1 - 0.0098 16.4 0.0 0.03 14.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.18 KPA39413.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CPT PF07931.12 KPA39413.1 - 0.051 13.4 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 KPA39413.1 - 0.14 12.4 0.0 0.44 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KPA39413.1 - 0.17 12.0 0.0 0.54 10.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KPA39414.1 - 7.6e-98 324.1 0.0 1.1e-47 161.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA39414.1 - 2.1e-23 81.9 3.1 7.5e-13 48.1 0.3 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KPA39414.1 - 3.1e-19 68.9 0.4 1.1e-18 67.1 0.4 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KPA39414.1 - 2.2e-14 53.5 0.1 3.2e-06 27.0 0.0 3.4 3 2 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KPA39414.1 - 8.7e-14 52.0 0.0 2.1e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KPA39414.1 - 8.7e-13 49.0 0.0 0.0014 19.0 0.0 4.5 3 2 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 KPA39414.1 - 5.6e-12 46.0 0.0 4.7e-05 23.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KPA39414.1 - 7e-12 45.5 0.4 3.5e-06 27.1 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPA39414.1 - 1.2e-09 38.6 0.3 0.023 15.0 0.0 4.1 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 KPA39414.1 - 3.6e-09 36.3 0.0 0.0012 18.2 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 KPA39414.1 - 5.6e-08 32.4 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 KPA39414.1 - 1.9e-07 31.7 0.0 0.029 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KPA39414.1 - 2.1e-07 30.5 0.3 0.0073 15.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KPA39414.1 - 2.2e-07 30.8 0.0 0.011 15.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KPA39414.1 - 2.8e-07 30.6 0.0 0.0082 16.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KPA39414.1 - 2.9e-07 30.3 3.3 0.18 11.4 0.1 4.5 3 2 0 4 4 4 3 AAA domain RNA_helicase PF00910.22 KPA39414.1 - 1.6e-06 28.4 0.0 0.091 13.2 0.0 2.9 3 0 0 3 3 2 2 RNA helicase DUF815 PF05673.13 KPA39414.1 - 1.9e-06 27.3 0.0 0.0034 16.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ATPase PF06745.13 KPA39414.1 - 2.3e-06 27.2 0.3 0.25 10.6 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 KPA39414.1 - 3.3e-06 26.7 0.0 0.055 13.0 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 KPA39414.1 - 4.4e-06 26.6 0.2 4.7e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_28 PF13521.6 KPA39414.1 - 1.1e-05 25.7 0.1 0.15 12.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 KPA39414.1 - 1.7e-05 25.3 0.0 0.23 12.0 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_24 PF13479.6 KPA39414.1 - 2.3e-05 24.2 0.0 0.083 12.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KPA39414.1 - 2.8e-05 23.9 0.1 0.24 11.1 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KPA39414.1 - 3.5e-05 23.0 0.0 0.2 10.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 KPA39414.1 - 0.00012 21.6 0.2 0.36 10.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein TsaE PF02367.17 KPA39414.1 - 0.00014 21.8 0.0 0.85 9.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 KPA39414.1 - 0.00016 21.6 0.0 0.12 12.2 0.0 2.7 3 0 0 3 3 2 1 Bacterial dnaA protein AAA_3 PF07726.11 KPA39414.1 - 0.00018 21.4 0.1 0.69 9.8 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KPA39414.1 - 0.00018 21.5 0.0 0.047 13.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 KPA39414.1 - 0.00032 21.1 0.0 0.6 10.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KPA39414.1 - 0.00036 20.5 0.1 0.44 10.4 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 KPA39414.1 - 0.00052 19.8 0.3 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KPA39414.1 - 0.0012 18.7 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KPA39414.1 - 0.0013 19.1 0.7 5.2 7.4 0.0 3.6 3 1 1 4 4 3 0 AAA domain ATPase_2 PF01637.18 KPA39414.1 - 0.0026 17.7 0.0 1.9 8.4 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 KPA39414.1 - 0.0032 17.6 0.0 0.51 10.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.9 KPA39414.1 - 0.0043 16.3 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KPA39414.1 - 0.0054 16.6 0.6 2.6 7.9 0.0 3.9 4 0 0 4 4 3 1 NTPase Viral_helicase1 PF01443.18 KPA39414.1 - 0.0074 16.0 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 KPA39414.1 - 0.009 15.3 0.0 0.87 8.8 0.0 3.0 2 1 1 3 3 3 1 KAP family P-loop domain NB-ARC PF00931.22 KPA39414.1 - 0.011 15.0 0.0 3.9 6.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain IPT PF01745.16 KPA39414.1 - 0.012 15.0 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UFD1 PF03152.14 KPA39414.1 - 0.023 14.2 0.0 0.17 11.4 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Zeta_toxin PF06414.12 KPA39414.1 - 0.023 14.0 0.3 7.6 5.8 0.0 2.8 3 0 0 3 3 2 0 Zeta toxin AAA_6 PF12774.7 KPA39414.1 - 0.056 12.4 0.2 7.6 5.4 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin PF02224.18 KPA39414.1 - 0.065 13.0 0.0 13 5.5 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase KTI12 PF08433.10 KPA39414.1 - 0.066 12.6 1.2 27 4.1 0.0 3.3 3 1 0 3 3 3 0 Chromatin associated protein KTI12 AFG1_ATPase PF03969.16 KPA39414.1 - 0.099 11.5 0.0 12 4.7 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Zot PF05707.12 KPA39414.1 - 0.14 11.7 0.0 2.4 7.7 0.0 2.9 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) EnY2 PF10163.9 KPA39415.1 - 0.033 14.5 0.1 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Transcription factor e(y)2 ERAP1_C PF11838.8 KPA39415.1 - 0.04 13.5 0.1 0.05 13.1 0.1 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Dimer_Tnp_hAT PF05699.14 KPA39416.1 - 6.4e-15 54.7 0.0 1.3e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Cyt_bd_oxida_II PF02322.15 KPA39417.1 - 0.016 14.6 13.7 0.019 14.3 13.7 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Amino_oxidase PF01593.24 KPA39422.1 - 2.5e-52 178.7 0.0 3.9e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA39422.1 - 1.8e-12 47.3 0.1 4.1e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA39422.1 - 1.1e-08 35.1 0.2 8.6e-08 32.1 0.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA39422.1 - 1.7e-07 30.8 0.0 5.7e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA39422.1 - 9.3e-07 28.3 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KPA39422.1 - 4.4e-06 26.0 0.0 6e-05 22.3 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPA39422.1 - 3.8e-05 22.9 0.1 6.6e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KPA39422.1 - 9.9e-05 22.8 0.2 0.00033 21.1 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA39422.1 - 0.00033 19.5 0.1 0.00073 18.3 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KPA39422.1 - 0.00037 20.5 0.1 0.0033 17.4 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KPA39422.1 - 0.00082 18.7 0.1 0.0013 18.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KPA39422.1 - 0.0014 18.1 0.0 0.0031 16.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA39422.1 - 0.0087 15.3 0.1 0.31 10.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA39422.1 - 0.011 14.9 0.1 0.048 12.8 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A DICT PF10069.9 KPA39422.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system Trp_halogenase PF04820.14 KPA39422.1 - 0.017 14.0 0.2 0.027 13.3 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Ribonuc_L-PSP PF01042.21 KPA39423.1 - 5.5e-14 52.2 0.1 7.2e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP LigT_PEase PF02834.16 KPA39423.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 LigT like Phosphoesterase Amidohydro_1 PF01979.20 KPA39424.1 - 3.5e-17 62.8 0.0 5.1e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPA39424.1 - 7.4e-09 35.6 0.0 0.0022 17.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PUA_3 PF17785.1 KPA39424.1 - 0.065 13.1 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 PUA-like domain ABC2_membrane PF01061.24 KPA39425.1 - 4.3e-69 232.1 58.3 3.2e-40 137.8 27.1 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KPA39425.1 - 1.2e-34 119.8 0.0 2.5e-16 60.4 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KPA39425.1 - 4.1e-32 109.9 6.1 2.7e-27 94.5 0.0 3.8 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KPA39425.1 - 6.4e-13 49.1 0.0 1.5e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KPA39425.1 - 9.8e-06 25.6 0.1 0.0048 16.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KPA39425.1 - 1.2e-05 25.0 1.3 0.0021 17.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KPA39425.1 - 1.5e-05 24.7 0.3 0.0002 21.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA39425.1 - 1.5e-05 25.5 0.2 0.026 14.9 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KPA39425.1 - 3.7e-05 23.9 0.0 0.069 13.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 KPA39425.1 - 4.3e-05 23.0 0.0 0.15 11.5 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KPA39425.1 - 8.4e-05 23.1 0.0 0.41 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KPA39425.1 - 0.0001 22.3 0.0 0.3 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KPA39425.1 - 0.0012 19.3 0.2 14 6.2 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KPA39425.1 - 0.0019 17.9 0.1 0.62 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KPA39425.1 - 0.003 17.8 0.3 1.4 9.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KPA39425.1 - 0.0043 16.2 38.0 0.015 14.5 19.2 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_23 PF13476.6 KPA39425.1 - 0.0052 17.3 0.1 0.13 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KPA39425.1 - 0.0054 16.7 0.4 1.4 8.8 0.1 2.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KPA39425.1 - 0.008 16.5 1.0 2.9 8.2 0.4 3.3 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 KPA39425.1 - 0.0085 16.5 0.8 3.5 8.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KPA39425.1 - 0.01 15.8 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KPA39425.1 - 0.055 13.5 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KPA39425.1 - 0.081 12.7 0.1 4.6 6.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.19 KPA39425.1 - 0.12 12.0 1.6 3.4 7.2 0.6 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 KPA39425.1 - 0.15 11.9 0.0 6.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Peptidase_C2 PF00648.21 KPA39427.1 - 4.7e-54 183.4 0.1 2.1e-39 135.3 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Peptidase_C47 PF05543.13 KPA39427.1 - 0.051 13.2 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Staphopain peptidase C47 EST1_DNA_bind PF10373.9 KPA39429.1 - 3.1e-14 53.1 0.0 1e-13 51.4 0.0 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain HALZ PF02183.18 KPA39430.1 - 0.00086 19.5 7.4 0.13 12.6 2.3 3.8 3 0 0 3 3 3 2 Homeobox associated leucine zipper DUF1664 PF07889.12 KPA39430.1 - 0.054 13.5 17.7 1.1 9.3 2.6 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DNA_pack_N PF02500.15 KPA39430.1 - 0.64 9.8 7.9 0.03 14.2 1.2 1.9 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus GP41 PF00517.17 KPA39430.1 - 0.97 9.3 4.7 0.83 9.5 2.0 2.2 2 0 0 2 2 2 0 Retroviral envelope protein DUF948 PF06103.11 KPA39430.1 - 1 9.7 12.7 2.6 8.4 0.0 4.3 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF2229 PF09989.9 KPA39430.1 - 8.1 6.0 7.7 18 4.9 0.4 2.5 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DnaJ PF00226.31 KPA39431.1 - 1.8e-07 31.2 0.4 7.1e-07 29.3 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain FAD_binding_8 PF08022.12 KPA39435.1 - 2.5e-10 40.4 0.1 6.5e-10 39.1 0.1 1.7 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KPA39435.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Deltameth_res PF16020.5 KPA39436.1 - 0.011 15.6 0.2 0.026 14.4 0.1 1.7 2 0 0 2 2 2 0 Deltamethrin resistance Patatin PF01734.22 KPA39437.1 - 3.2e-13 50.3 0.3 6.8e-13 49.3 0.3 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase DNA_pol3_gamma3 PF12169.8 KPA39438.1 - 0.0081 16.1 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III S6OS1 PF15676.5 KPA39438.1 - 0.077 11.5 0.2 0.11 10.9 0.2 1.2 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Fungal_trans_2 PF11951.8 KPA39439.1 - 2.4e-09 36.5 0.1 4.2e-09 35.7 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain bZIP_C PF12498.8 KPA39439.1 - 0.11 13.5 0.4 0.2 12.6 0.4 1.4 1 0 0 1 1 1 0 Basic leucine-zipper C terminal Sugar_tr PF00083.24 KPA39441.1 - 1.1e-83 281.7 23.4 1.3e-83 281.4 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA39441.1 - 2.3e-16 59.7 25.0 2.3e-16 59.7 25.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily CBM_1 PF00734.18 KPA39443.1 - 1.8e-11 43.8 11.5 2.1e-11 43.6 8.7 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KPA39443.1 - 0.0097 16.1 0.9 0.019 15.2 0.9 1.5 1 0 0 1 1 1 1 Toxin 7 DUF4246 PF14033.6 KPA39444.1 - 4.2e-170 566.7 0.0 5.3e-170 566.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KPA39444.1 - 0.017 15.5 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Sigma70_ner PF04546.13 KPA39444.1 - 0.3 10.9 3.9 0.55 10.1 3.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 KPA39444.1 - 4.7 6.5 6.1 6.8 6.0 6.1 1.2 1 0 0 1 1 1 0 SDA1 MF_alpha_N PF05436.11 KPA39445.1 - 0.095 12.6 0.5 0.21 11.5 0.5 1.8 1 1 0 1 1 1 0 Mating factor alpha precursor N-terminus MFS_1 PF07690.16 KPA39446.1 - 7e-28 97.6 22.7 7e-28 97.6 22.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPA39446.1 - 1.6e-08 34.3 3.5 3.9e-08 33.0 3.5 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PUCC PF03209.15 KPA39446.1 - 0.017 14.1 5.3 0.021 13.8 3.8 1.8 2 0 0 2 2 2 0 PUCC protein Polysacc_synt_C PF14667.6 KPA39446.1 - 0.05 13.7 0.1 0.05 13.7 0.1 4.0 3 1 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DUF485 PF04341.12 KPA39446.1 - 0.29 11.1 6.3 0.3 11.1 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function, DUF485 HpcH_HpaI PF03328.14 KPA39447.1 - 7.5e-27 93.9 0.0 1.3e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Fungal_trans PF04082.18 KPA39447.1 - 9.7e-12 44.5 0.2 1.6e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA39447.1 - 1.1e-07 31.8 9.2 2e-07 31.0 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP-utilizers_C PF02896.18 KPA39447.1 - 0.0071 15.5 0.1 0.032 13.3 0.1 2.0 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain 2-Hacid_dh_C PF02826.19 KPA39448.1 - 1.6e-48 164.4 0.0 2.7e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPA39448.1 - 1.3e-22 79.9 0.0 2.4e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KPA39448.1 - 3.1e-05 24.1 0.1 6e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KPA39448.1 - 0.004 17.3 0.0 0.0093 16.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KPA39448.1 - 0.046 14.3 0.1 0.29 11.7 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KPA39448.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sugar_tr PF00083.24 KPA39449.1 - 5.4e-87 292.5 27.6 6.6e-87 292.2 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA39449.1 - 5.9e-21 74.8 13.9 5.9e-21 74.8 13.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily SGL PF08450.12 KPA39450.1 - 7.8e-28 97.7 0.0 9.7e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KPA39450.1 - 2.2e-05 24.6 0.0 0.01 16.0 0.0 2.3 2 0 0 2 2 2 2 Arylesterase Str_synth PF03088.16 KPA39450.1 - 0.00011 22.3 0.0 0.00086 19.4 0.0 2.3 2 1 1 3 3 3 1 Strictosidine synthase NHL PF01436.21 KPA39450.1 - 0.00034 20.5 0.0 0.28 11.3 0.0 3.9 4 0 0 4 4 4 1 NHL repeat Lactonase PF10282.9 KPA39450.1 - 0.022 14.1 0.0 0.054 12.7 0.0 1.6 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller UvrD_C_2 PF13538.6 KPA39450.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF5122 PF17164.4 KPA39450.1 - 0.13 12.6 0.3 0.44 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller SGL PF08450.12 KPA39451.1 - 4.8e-06 26.3 0.0 6.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KPA39451.1 - 0.012 15.6 1.1 1.8 8.8 0.0 2.9 3 0 0 3 3 3 0 NHL repeat SBBP PF06739.11 KPA39451.1 - 0.018 15.0 0.7 2.8 8.0 0.0 2.7 3 0 0 3 3 3 0 Beta-propeller repeat Egh16-like PF11327.8 KPA39452.1 - 4.4e-70 235.8 1.9 8.4e-70 234.9 1.9 1.4 1 1 0 1 1 1 1 Egh16-like virulence factor Peptidase_M28 PF04389.17 KPA39453.1 - 1.5e-29 103.1 0.1 3.2e-29 102.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 KPA39453.1 - 0.00011 22.0 0.1 0.00046 19.9 0.1 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4127 PF13552.6 KPA39453.1 - 0.034 12.8 0.1 0.047 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) p450 PF00067.22 KPA39454.1 - 1.4e-66 225.1 0.0 1.7e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2459 PF09601.10 KPA39454.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) GT-D PF08759.11 KPA39454.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold DUF3519 PF12033.8 KPA39454.1 - 0.12 12.8 0.4 0.24 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) adh_short PF00106.25 KPA39455.1 - 8e-39 133.1 0.3 1.4e-38 132.3 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA39455.1 - 2.8e-33 115.4 0.1 1.8e-31 109.5 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA39455.1 - 1.3e-10 41.4 0.8 2.7e-09 37.2 0.1 2.2 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.10 KPA39455.1 - 0.0012 18.3 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KPA39455.1 - 0.093 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HMG-CoA_red PF00368.18 KPA39456.1 - 6.2e-81 272.2 0.0 7.4e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase DUF4596 PF15363.6 KPA39456.1 - 0.19 12.0 1.4 0.34 11.2 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Chromo PF00385.24 KPA39458.1 - 8.4e-07 28.8 3.0 1.8e-05 24.6 0.1 2.7 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Lipocalin_9 PF17186.4 KPA39458.1 - 0.053 13.8 0.0 0.092 13.0 0.0 1.4 1 1 0 1 1 1 0 Lipocalin-like domain Ank_2 PF12796.7 KPA39460.1 - 4.3e-50 168.2 11.7 1.9e-12 47.6 0.3 6.2 5 1 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA39460.1 - 8e-37 121.1 20.0 0.00024 21.3 0.1 11.4 11 0 0 11 11 11 10 Ankyrin repeat Ank PF00023.30 KPA39460.1 - 6.2e-36 121.3 33.3 1.7e-07 31.4 1.5 10.6 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 KPA39460.1 - 1.3e-35 121.3 22.2 2.2e-08 34.5 0.3 8.6 4 2 6 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA39460.1 - 1.6e-30 104.7 13.8 1.6e-09 37.8 0.3 9.1 3 3 8 11 11 11 7 Ankyrin repeats (many copies) SDH_alpha PF03313.15 KPA39460.1 - 0.013 15.2 0.1 0.028 14.1 0.1 1.8 1 1 0 1 1 1 0 Serine dehydratase alpha chain DUF4988 PF16378.5 KPA39460.1 - 0.075 12.7 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function NepR PF18557.1 KPA39461.1 - 0.025 14.2 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Anti-sigma factor NepR Cyclin_N PF00134.23 KPA39462.1 - 2.1e-36 124.4 1.8 3e-36 124.0 0.5 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KPA39462.1 - 5.9e-09 36.1 1.0 6.2e-07 29.5 0.2 3.1 2 1 0 2 2 2 1 Cyclin, C-terminal domain MFS_1 PF07690.16 KPA39463.1 - 2e-16 59.9 18.4 3.1e-12 46.1 9.0 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA39463.1 - 0.0049 15.8 6.6 0.0064 15.4 6.6 1.3 1 0 0 1 1 1 1 MFS_1 like family Patatin PF01734.22 KPA39464.1 - 5.7e-15 56.0 0.1 1.9e-14 54.4 0.1 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.6 KPA39464.1 - 2.5 8.0 5.7 11 6.0 5.7 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EHN PF06441.12 KPA39465.1 - 2.6e-27 95.3 0.0 5.2e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPA39465.1 - 3.1e-06 27.0 0.1 6e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA39465.1 - 0.00032 21.4 2.8 0.00055 20.6 1.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Glyoxal_oxid_N PF07250.11 KPA39466.1 - 0.17 11.0 0.6 0.28 10.3 0.6 1.2 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus AA_permease PF00324.21 KPA39467.1 - 3.4e-127 425.0 37.6 5.3e-127 424.3 37.6 1.2 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.13 KPA39467.1 - 3.8e-36 125.0 0.0 6.1e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold AA_permease_2 PF13520.6 KPA39467.1 - 4.4e-28 98.3 40.7 4.1e-27 95.1 40.7 2.0 1 1 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KPA39467.1 - 0.0013 17.7 0.3 0.0027 16.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4781) DUF2974 PF11187.8 KPA39467.1 - 0.0018 17.9 0.0 0.0038 16.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Peptidase_S15 PF02129.18 KPA39467.1 - 0.068 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BTB PF00651.31 KPA39468.1 - 3.3e-14 53.1 0.0 2.2e-13 50.4 0.0 2.2 2 1 1 3 3 3 1 BTB/POZ domain Dsh_C PF12316.8 KPA39469.1 - 0.00054 20.4 9.3 0.00081 19.9 9.3 1.2 1 0 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal DUF4172 PF13776.6 KPA39469.1 - 0.056 13.8 0.0 0.26 11.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) ABC_tran PF00005.27 KPA39470.1 - 4.4e-34 118.0 0.0 1.4e-33 116.3 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KPA39470.1 - 4e-32 112.0 10.3 4e-32 112.0 10.3 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KPA39470.1 - 3.7e-06 26.6 0.3 0.00056 19.4 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KPA39470.1 - 0.00083 19.6 0.3 0.0039 17.5 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KPA39470.1 - 0.011 15.5 0.5 0.026 14.3 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KPA39470.1 - 0.012 16.0 0.8 0.12 12.7 0.8 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KPA39470.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KPA39470.1 - 0.026 14.8 0.6 0.32 11.3 0.6 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Gaa1 PF04114.14 KPA39470.1 - 0.031 13.3 0.0 0.031 13.3 0.0 2.1 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component AAA_10 PF12846.7 KPA39470.1 - 0.038 12.9 0.2 0.078 11.9 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.6 KPA39470.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 KPA39470.1 - 0.17 12.0 0.8 0.3 11.1 0.2 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain DUF3278 PF11683.8 KPA39470.1 - 0.68 10.0 5.3 0.36 10.9 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3278) Polyketide_cyc2 PF10604.9 KPA39471.1 - 1.4e-07 31.9 0.1 1.6e-07 31.7 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4520 PF15016.6 KPA39471.1 - 0.054 13.6 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) PAP2_3 PF14378.6 KPA39472.1 - 1.5e-27 96.5 16.5 3.2e-22 79.1 3.9 2.3 2 0 0 2 2 2 2 PAP2 superfamily PAP2_C PF14360.6 KPA39472.1 - 0.017 15.6 0.8 0.017 15.6 0.8 3.0 3 0 0 3 3 3 0 PAP2 superfamily C-terminal PAP2 PF01569.21 KPA39472.1 - 0.034 13.9 6.3 0.043 13.6 4.7 2.0 1 1 0 1 1 1 0 PAP2 superfamily Gly_transf_sug PF04488.15 KPA39473.1 - 3.8e-18 65.9 0.1 8.3e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KPA39473.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 KPA39473.1 - 0.0079 15.5 0.2 0.031 13.6 0.0 1.9 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain GST_C_3 PF14497.6 KPA39474.1 - 5.5e-19 68.2 0.2 1e-18 67.3 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA39474.1 - 3.8e-05 23.8 0.1 9.3e-05 22.6 0.1 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPA39474.1 - 0.0025 17.8 0.0 0.0045 17.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KPA39474.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Tyrosinase PF00264.20 KPA39475.1 - 1.3e-36 127.0 1.6 1.8e-36 126.5 1.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase AA_permease PF00324.21 KPA39477.1 - 5.8e-134 447.3 38.1 7.2e-134 447.0 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA39477.1 - 2.6e-37 128.7 40.0 3.2e-37 128.4 40.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KPA39477.1 - 0.0051 15.7 1.1 0.011 14.6 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4781) PEX11 PF05648.14 KPA39478.1 - 9.3e-32 110.3 2.6 1e-31 110.2 2.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SKG6 PF08693.10 KPA39479.1 - 0.00012 21.4 0.5 0.00032 20.0 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 KPA39479.1 - 0.00067 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity RicinB_lectin_2 PF14200.6 KPA39479.1 - 0.0014 19.3 4.0 0.023 15.4 1.6 2.7 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like VSP PF03302.13 KPA39479.1 - 0.0024 16.8 0.1 0.0038 16.1 0.1 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 KPA39479.1 - 0.0031 17.6 0.1 0.0048 17.0 0.1 1.3 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.12 KPA39479.1 - 0.0063 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4448 PF14610.6 KPA39479.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Botulinum_HA-17 PF05588.11 KPA39479.1 - 0.13 12.4 0.1 0.44 10.7 0.1 1.8 1 1 0 1 1 1 0 Clostridium botulinum HA-17 domain SSP160 PF06933.11 KPA39479.1 - 4.3 5.4 10.5 5.7 5.0 10.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Cellulase PF00150.18 KPA39480.1 - 3e-52 177.8 6.8 4e-52 177.4 6.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KPA39480.1 - 3.7e-12 46.0 9.4 3.7e-12 46.0 9.4 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KPA39480.1 - 0.0059 16.8 1.2 0.0059 16.8 1.2 1.8 2 0 0 2 2 2 1 Toxin 7 SPRY PF00622.28 KPA39481.1 - 2.3e-05 24.5 0.1 3.9e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 SPRY domain Ank_2 PF12796.7 KPA39482.1 - 9e-20 71.1 1.0 0.00018 22.0 0.0 5.1 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA39482.1 - 1.1e-14 54.3 0.1 0.0039 17.5 0.0 6.6 5 2 1 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPA39482.1 - 1.4e-12 47.8 0.3 0.22 12.2 0.0 6.4 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA39482.1 - 8.7e-09 34.9 0.4 0.34 11.6 0.0 6.1 6 1 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 KPA39482.1 - 1.3e-08 34.9 3.1 0.13 12.7 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeat Spt4 PF06093.13 KPA39482.1 - 0.23 11.6 1.4 24 5.1 0.5 2.7 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger AIM24 PF01987.17 KPA39484.1 - 4.7e-48 163.6 0.6 5.4e-48 163.4 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Lactonase PF10282.9 KPA39485.1 - 2.3e-22 79.8 0.6 3e-22 79.4 0.6 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller CMD PF02627.20 KPA39486.1 - 2.2e-05 24.4 0.0 3.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family PRMT5_C PF17286.2 KPA39486.1 - 0.11 12.3 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain MmgE_PrpD PF03972.14 KPA39487.1 - 3.3e-11 42.4 0.0 3.4e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PS-DH PF14765.6 KPA39488.1 - 9.9e-66 222.0 0.0 1.6e-65 221.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KPA39488.1 - 3.2e-58 196.6 0.1 6.6e-58 195.6 0.1 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KPA39488.1 - 4.9e-48 164.3 0.1 8.7e-48 163.4 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.12 KPA39488.1 - 1.4e-17 64.3 0.0 5.8e-17 62.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 KPA39488.1 - 3.3e-16 59.4 0.0 1.2e-15 57.6 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA39488.1 - 5.6e-12 46.9 0.0 8e-11 43.1 0.0 2.8 2 1 1 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KPA39488.1 - 6.5e-12 46.0 0.0 5.4e-09 36.6 0.0 3.8 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA39488.1 - 4.2e-10 39.7 0.0 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KPA39488.1 - 1.3e-09 37.8 0.1 3.1e-08 33.3 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KPA39488.1 - 6.9e-09 35.7 0.0 2.2e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA39488.1 - 3.8e-08 33.9 0.0 2.2e-06 28.2 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain adh_short_C2 PF13561.6 KPA39488.1 - 2.8e-06 27.1 0.0 5e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KPA39488.1 - 2.4e-05 24.2 0.2 5.1e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KPA39488.1 - 3.3e-05 24.1 0.0 9.3e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.9 KPA39488.1 - 0.0003 20.6 0.0 0.0059 16.4 0.0 2.4 2 0 0 2 2 2 1 Lysine methyltransferase RrnaAD PF00398.20 KPA39488.1 - 0.033 13.2 0.0 0.13 11.3 0.0 1.9 1 1 1 2 2 2 0 Ribosomal RNA adenine dimethylase HipN PF18253.1 KPA39488.1 - 0.086 12.5 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain Methyltransf_28 PF02636.17 KPA39488.1 - 0.094 12.3 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 KPA39488.1 - 0.11 12.2 0.0 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FMN_dh PF01070.18 KPA39489.1 - 5.5e-100 334.8 0.1 1.3e-95 320.4 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KPA39489.1 - 0.0014 17.9 0.1 0.003 16.7 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 KPA39489.1 - 0.013 14.5 0.2 0.028 13.4 0.2 1.6 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KPA39489.1 - 0.028 13.7 0.2 0.48 9.7 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Epimerase PF01370.21 KPA39490.1 - 7.8e-20 71.4 0.0 9.7e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA39490.1 - 4.6e-10 39.4 0.0 7.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPA39490.1 - 2.4e-09 36.6 0.0 3.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPA39490.1 - 6.3e-09 35.4 0.1 0.00018 20.7 0.0 2.6 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KPA39490.1 - 2.5e-05 23.5 0.0 3.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KPA39490.1 - 0.0025 17.0 0.0 0.021 14.0 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KPA39490.1 - 0.0096 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding BNR_2 PF13088.6 KPA39491.1 - 5.4e-64 216.2 1.2 6.9e-64 215.8 1.2 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KPA39491.1 - 0.00036 20.1 16.5 0.78 10.0 0.0 5.4 6 0 0 6 6 6 3 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KPA39491.1 - 0.0008 18.3 0.0 0.0088 14.9 0.0 2.3 2 1 0 2 2 2 1 Sortilin, neurotensin receptor 3, Aldo_ket_red PF00248.21 KPA39492.1 - 6.7e-68 229.0 0.0 7.5e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 KPA39493.1 - 0.11 11.4 0.2 0.21 10.6 0.2 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain SBD_N PF07005.11 KPA39494.1 - 1.3e-58 198.4 0.0 2.5e-58 197.5 0.0 1.4 2 0 0 2 2 2 1 Sugar-binding N-terminal domain NBD_C PF17042.5 KPA39494.1 - 1.5e-42 146.0 0.0 2.8e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain FAD_binding_4 PF01565.23 KPA39496.1 - 2.6e-23 82.3 0.4 2.6e-23 82.3 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KPA39496.1 - 0.00022 21.2 0.1 0.00083 19.4 0.1 2.0 1 0 0 1 1 1 1 Berberine and berberine like Melibiase PF02065.18 KPA39498.1 - 6.8e-143 475.8 0.0 8.4e-143 475.5 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KPA39498.1 - 9.4e-79 264.5 0.0 1.3e-78 264.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 KPA39498.1 - 1.6e-20 73.4 0.0 3.5e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 KPA39498.1 - 0.00041 19.5 0.1 0.00065 18.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Na_Ca_ex PF01699.24 KPA39499.1 - 9.7e-28 97.0 20.8 3.1e-15 56.4 9.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SecD_SecF PF02355.16 KPA39499.1 - 0.0031 16.9 3.3 0.61 9.4 0.5 2.8 2 0 0 2 2 2 2 Protein export membrane protein DUF2206 PF09971.9 KPA39499.1 - 0.025 13.3 2.4 0.25 10.1 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) Herpes_UL73 PF03554.13 KPA39499.1 - 0.56 10.2 0.0 0.56 10.2 0.0 3.0 3 1 1 4 4 4 0 UL73 viral envelope glycoprotein Ninjurin PF04923.12 KPA39499.1 - 1.1 9.3 5.2 3.9 7.5 0.2 3.2 3 0 0 3 3 3 0 Ninjurin Glutaminase PF04960.15 KPA39500.1 - 5.1e-112 373.7 0.1 6.2e-112 373.4 0.1 1.1 1 0 0 1 1 1 1 Glutaminase GSHPx PF00255.19 KPA39502.1 - 0.19 11.3 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Glutathione peroxidase NTPase_I-T PF01931.18 KPA39503.1 - 3.7e-57 192.6 0.0 4.2e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 SNARE PF05739.19 KPA39506.1 - 1.4e-14 53.8 0.2 1.4e-14 53.8 0.2 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 KPA39506.1 - 1.1e-08 34.0 1.9 1.3e-08 33.8 0.2 2.1 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 KPA39506.1 - 0.00033 20.9 5.3 0.044 14.1 0.1 3.4 4 0 0 4 4 4 2 Uncharacterized conserved protein Prominin PF05478.11 KPA39506.1 - 0.00056 18.0 2.3 0.39 8.6 0.9 2.2 2 0 0 2 2 2 2 Prominin Syntaxin PF00804.25 KPA39506.1 - 0.0025 17.5 0.1 0.0025 17.5 0.1 3.3 2 1 0 3 3 3 1 Syntaxin Syntaxin-18_N PF10496.9 KPA39506.1 - 0.014 15.7 1.3 0.1 12.9 0.2 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4988 PF16378.5 KPA39506.1 - 0.083 12.5 4.9 8.3 6.0 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function TRPM_tetra PF16519.5 KPA39506.1 - 0.1 12.7 3.4 0.17 12.0 0.1 2.9 3 0 0 3 3 3 0 Tetramerisation domain of TRPM NPV_P10 PF05531.12 KPA39506.1 - 0.2 12.2 4.9 19 5.8 1.7 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 KPA39506.1 - 0.63 9.8 10.0 0.091 12.6 0.8 2.6 3 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FliS_cochap PF16522.5 KPA39506.1 - 1.4 8.9 5.8 10 6.1 0.1 3.3 3 1 0 3 3 3 0 Flagellar FLiS export co-chaperone, HP1076 SF-assemblin PF06705.11 KPA39506.1 - 1.7 7.9 7.3 0.57 9.5 0.7 2.6 3 0 0 3 3 3 0 SF-assemblin/beta giardin DUF16 PF01519.16 KPA39506.1 - 6.1 7.4 7.7 2.7 8.5 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 Aldo_ket_red PF00248.21 KPA39507.1 - 1.8e-40 139.0 0.1 2.6e-38 131.9 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 KPA39508.1 - 4.9e-28 97.2 1.4 4.9e-28 97.2 1.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA39508.1 - 5.2e-18 65.3 1.5 1.1e-17 64.2 1.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPA39508.1 - 3.1e-13 49.7 2.8 1.1e-06 28.3 0.1 2.3 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 KPA39508.1 - 0.00058 19.1 0.8 0.00084 18.5 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KPA39508.1 - 0.00078 18.8 1.5 0.00078 18.8 1.5 2.0 1 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KPA39508.1 - 0.018 13.8 0.8 0.03 13.0 0.8 1.3 1 0 0 1 1 1 0 HI0933-like protein ADH_N_2 PF16884.5 KPA39508.1 - 0.065 13.1 0.3 0.64 10.0 0.0 2.6 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase YdfZ PF14001.6 KPA39508.1 - 0.096 13.1 0.2 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 YdfZ protein 2-Hacid_dh_C PF02826.19 KPA39508.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KPA39508.1 - 0.13 12.8 0.5 0.29 11.6 0.5 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding VWA_2 PF13519.6 KPA39508.1 - 0.14 12.8 0.0 0.57 10.9 0.0 2.0 1 1 1 2 2 2 0 von Willebrand factor type A domain adh_short_C2 PF13561.6 KPA39509.1 - 1.6e-55 188.3 0.0 2e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA39509.1 - 2.1e-51 174.2 1.3 2.3e-51 174.1 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPA39509.1 - 8.7e-13 48.6 0.4 2e-12 47.4 0.4 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA39509.1 - 8e-09 35.3 0.0 1.8e-08 34.1 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KPA39509.1 - 0.0096 15.0 0.2 0.022 13.9 0.1 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KPA39509.1 - 0.027 14.7 0.0 4.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KPA39509.1 - 0.065 12.8 2.8 0.096 12.2 0.8 2.2 2 1 0 2 2 2 0 NmrA-like family PALP PF00291.25 KPA39509.1 - 0.077 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 KPA39509.1 - 0.078 13.0 0.4 0.15 12.1 0.1 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 KPA39509.1 - 0.097 12.1 0.3 0.24 10.7 0.1 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1815 PF08844.10 KPA39509.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) 2-Hacid_dh_C PF02826.19 KPA39509.1 - 0.14 11.5 0.0 0.32 10.3 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LDcluster4 PF18306.1 KPA39509.1 - 0.15 11.6 1.2 0.17 11.5 0.1 1.5 2 0 0 2 2 2 0 SLOG cluster4 family Acetyltransf_1 PF00583.25 KPA39510.1 - 2.3e-10 40.7 0.0 2.8e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA39510.1 - 1.9e-07 31.1 0.1 2.5e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA39510.1 - 3.1e-07 30.7 0.1 4.4e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Lipase_3 PF01764.25 KPA39511.1 - 2.9e-15 56.4 0.0 5.2e-14 52.3 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KPA39511.1 - 0.002 18.8 0.3 0.0047 17.6 0.3 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA39511.1 - 0.063 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_hydro_43 PF04616.14 KPA39512.1 - 2.1e-27 96.2 1.3 3.4e-26 92.2 1.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 DUF2052 PF09747.9 KPA39513.1 - 1.1e-23 84.4 12.2 7.3e-12 45.8 5.0 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) pKID PF02173.17 KPA39513.1 - 0.0095 15.4 0.1 0.021 14.3 0.1 1.6 1 0 0 1 1 1 1 pKID domain GAGE PF05831.11 KPA39513.1 - 0.051 14.1 0.3 0.051 14.1 0.3 1.8 2 0 0 2 2 2 0 GAGE protein Response_reg PF00072.24 KPA39514.1 - 3.2e-21 75.6 0.0 4.6e-15 55.7 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Secretin_N PF03958.17 KPA39514.1 - 2.6 8.5 0.0 2.6 8.5 0.0 3.1 2 1 0 2 2 2 0 Bacterial type II/III secretion system short domain Bot1p PF12298.8 KPA39515.1 - 2.8e-50 170.9 5.1 4.1e-50 170.3 5.1 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein TnsD PF15978.5 KPA39515.1 - 0.049 12.6 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D Y_phosphatase3 PF13350.6 KPA39516.1 - 1.2e-60 205.4 0.0 1.3e-60 205.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KPA39516.1 - 0.0016 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KPA39516.1 - 0.0025 17.4 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KPA39516.1 - 0.015 15.2 0.0 0.049 13.5 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 KPA39516.1 - 0.26 10.2 0.0 0.39 9.6 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain MARVEL PF01284.23 KPA39517.1 - 0.0012 18.9 18.6 0.021 14.9 11.3 2.3 1 1 1 2 2 2 2 Membrane-associating domain TctA PF01970.16 KPA39517.1 - 0.023 13.4 0.4 0.023 13.4 0.4 1.5 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctA family DUF4293 PF14126.6 KPA39517.1 - 0.023 14.9 1.6 0.031 14.5 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) MpPF26 PF07666.11 KPA39517.1 - 0.055 13.6 0.6 0.055 13.6 0.6 1.8 1 1 1 2 2 2 0 M penetrans paralogue family 26 VIT1 PF01988.19 KPA39517.1 - 0.59 10.0 3.9 0.33 10.8 1.9 1.6 1 1 1 2 2 2 0 VIT family Tetraspanin PF00335.20 KPA39517.1 - 0.76 9.4 7.8 0.62 9.7 6.5 1.4 1 1 0 1 1 1 0 Tetraspanin family DUF4234 PF14018.6 KPA39517.1 - 0.88 9.7 8.5 6.9 6.9 0.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) Claudin_3 PF06653.11 KPA39517.1 - 3 7.8 9.5 18 5.2 2.6 3.0 1 1 1 2 2 2 0 Tight junction protein, Claudin-like Methyltransf_23 PF13489.6 KPA39518.1 - 2e-19 70.0 0.0 3.7e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA39518.1 - 1.1e-13 51.7 0.0 5.1e-13 49.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA39518.1 - 2.5e-12 47.3 0.0 8.4e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA39518.1 - 1.5e-09 37.8 0.0 4.3e-08 33.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA39518.1 - 2e-07 31.7 0.0 1.6e-06 28.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA39518.1 - 4.8e-06 26.1 0.0 3.5e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KPA39518.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KPA39518.1 - 0.0029 17.2 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KPA39518.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KPA39518.1 - 0.029 13.8 0.0 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.19 KPA39518.1 - 0.052 13.3 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KPA39518.1 - 0.07 12.4 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 KPA39518.1 - 0.12 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 KPA39518.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase AA_permease PF00324.21 KPA39519.1 - 7.3e-117 390.9 33.7 8.2e-117 390.7 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA39519.1 - 1.2e-36 126.5 33.7 1.5e-36 126.1 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.23 KPA39520.1 - 1.4e-08 34.5 0.1 0.0036 17.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain ALO PF04030.14 KPA39520.1 - 4.5e-07 30.0 2.2 1.5e-06 28.3 2.2 1.8 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Chol_subst-bind PF09129.11 KPA39520.1 - 0.025 13.5 5.6 0.94 8.4 0.2 2.9 2 1 0 2 2 2 0 Cholesterol oxidase, substrate-binding MAD PF05557.13 KPA39521.1 - 3.6e-68 230.5 77.3 5.9e-68 229.8 74.0 1.9 1 1 1 2 2 2 2 Mitotic checkpoint protein Sirohm_synth_C PF14823.6 KPA39521.1 - 0.11 12.1 2.3 5.1 6.8 0.9 3.4 3 0 0 3 3 3 0 Sirohaem biosynthesis protein C-terminal Fib_alpha PF08702.10 KPA39521.1 - 5.3 7.2 60.0 0.19 11.9 11.5 5.6 2 2 2 5 5 5 0 Fibrinogen alpha/beta chain family Tam41_Mmp37 PF09139.11 KPA39522.1 - 2.5e-122 408.4 0.0 3.4e-122 407.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial muHD PF10291.9 KPA39523.1 - 4.5e-63 213.2 0.0 1.4e-62 211.6 0.0 1.8 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KPA39523.1 - 7.7e-09 35.7 0.2 2e-08 34.4 0.2 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain BAR_3 PF16746.5 KPA39523.1 - 0.0015 18.3 5.2 0.0024 17.6 5.2 1.2 1 0 0 1 1 1 1 BAR domain of APPL family Cys_Met_Meta_PP PF01053.20 KPA39523.1 - 0.0038 15.8 0.1 0.0078 14.8 0.1 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Vps5 PF09325.10 KPA39523.1 - 0.058 12.9 3.8 0.059 12.9 0.5 2.0 1 1 0 2 2 2 0 Vps5 C terminal like Muted PF14942.6 KPA39523.1 - 0.26 11.6 5.2 0.35 11.2 1.3 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF922 PF06037.11 KPA39523.1 - 0.39 10.5 2.3 0.64 9.8 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) Rsd_AlgQ PF04353.13 KPA39523.1 - 1.1 9.2 3.9 7.1 6.6 0.5 2.5 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Pkinase PF00069.25 KPA39524.1 - 3.3e-34 118.5 0.0 4.1e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA39524.1 - 8.9e-11 41.6 0.0 1.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPA39524.1 - 0.00053 18.9 0.0 0.00075 18.4 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KPA39524.1 - 0.089 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 zf-AD PF07776.15 KPA39525.1 - 0.15 12.3 0.0 0.51 10.6 0.0 1.8 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-RING_2 PF13639.6 KPA39526.1 - 1.4e-08 34.9 9.2 3.4e-08 33.7 9.2 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KPA39526.1 - 1.4e-05 25.2 8.5 4.1e-05 23.7 8.5 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KPA39526.1 - 0.00029 21.1 7.7 0.00086 19.5 7.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KPA39526.1 - 0.00039 20.4 2.6 0.0012 18.9 2.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KPA39526.1 - 0.00094 19.0 10.1 0.00094 19.0 10.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KPA39526.1 - 0.003 17.4 2.7 0.003 17.4 2.7 1.9 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 KPA39526.1 - 0.0033 17.5 7.8 0.0074 16.4 7.8 1.7 1 0 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 KPA39526.1 - 0.011 15.3 5.3 0.024 14.3 5.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KPA39526.1 - 0.02 14.7 8.6 0.044 13.6 8.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KPA39526.1 - 0.073 13.4 8.2 0.15 12.4 8.2 1.5 1 0 0 1 1 1 0 RING-like domain NUC130_3NT PF08158.12 KPA39526.1 - 0.1 13.0 2.3 24 5.3 0.1 4.7 4 1 1 5 5 5 0 NUC130/3NT domain zf-RING_9 PF13901.6 KPA39526.1 - 0.7 9.8 6.4 1.7 8.6 6.4 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-C3HC4_3 PF13920.6 KPA39526.1 - 2 8.3 12.3 0.052 13.4 5.9 1.7 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KPA39526.1 - 2.4 8.1 7.0 5.3 7.0 7.0 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 KPA39526.1 - 7.3 6.5 8.0 2.5e+02 1.6 8.0 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Hormone_3 PF00159.18 KPA39527.1 - 5.2 7.2 16.1 30 4.8 0.1 7.1 8 0 0 8 8 8 0 Pancreatic hormone peptide NUDE_C PF04880.13 KPA39528.1 - 0.025 15.1 1.2 0.026 15.0 1.2 1.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Bac_small_YrzI PF09501.10 KPA39528.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Glyco_hydro_3_C PF01915.22 KPA39531.1 - 3e-53 180.8 0.0 4.8e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPA39531.1 - 1.4e-34 119.9 0.0 5.1e-34 118.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPA39531.1 - 2.7e-25 88.3 0.0 5.5e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain B_lectin PF01453.24 KPA39533.1 - 2.8e-11 43.9 0.2 7.2e-05 23.3 0.0 2.2 1 1 1 2 2 2 2 D-mannose binding lectin PQQ_2 PF13360.6 KPA39533.1 - 0.0048 16.5 0.1 0.0059 16.2 0.1 1.2 1 0 0 1 1 1 1 PQQ-like domain BofC_C PF08955.10 KPA39533.1 - 0.037 14.1 0.0 14 5.8 0.0 2.7 2 1 1 3 3 3 0 BofC C-terminal domain Tubulin PF00091.25 KPA39534.1 - 9.9e-68 228.2 0.0 1.5e-67 227.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KPA39534.1 - 2.6e-45 153.7 0.2 6.4e-45 152.4 0.0 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KPA39534.1 - 2.8e-07 30.9 0.5 5.9e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KPA39534.1 - 0.11 12.2 0.0 0.37 10.4 0.0 1.9 1 0 0 1 1 1 0 Tubulin domain Ran_BP1 PF00638.18 KPA39535.1 - 2.4e-11 44.0 0.5 5.1e-11 42.9 0.5 1.5 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 KPA39535.1 - 6.3e-08 33.4 74.0 0.00029 21.6 24.4 10.0 3 2 8 11 11 11 5 Nucleoporin FG repeat region N_BRCA1_IG PF16158.5 KPA39536.1 - 5.6e-36 123.4 0.5 2e-35 121.6 0.0 2.3 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KPA39536.1 - 1.6e-20 72.6 61.6 2.6e-07 30.3 7.6 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KPA39536.1 - 0.0014 18.9 50.8 0.047 14.0 10.7 4.6 4 0 0 4 4 4 3 C1 domain Btz PF09405.10 KPA39537.1 - 1.2e-27 96.7 0.7 2.7e-27 95.6 0.7 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Serglycin PF04360.12 KPA39537.1 - 0.17 11.8 1.2 0.36 10.8 1.2 1.5 1 0 0 1 1 1 0 Serglycin Fungal_trans PF04082.18 KPA39538.1 - 7.6e-13 48.1 0.4 1.4e-12 47.2 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TSC22 PF01166.18 KPA39538.1 - 0.12 12.7 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Pyridoxal_deC PF00282.19 KPA39539.1 - 2.3e-104 349.1 0.0 2.7e-104 348.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Nucleotid_trans PF03407.16 KPA39540.1 - 5.8e-10 39.5 0.4 1e-09 38.7 0.4 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 KPA39540.1 - 4.9e-08 33.0 2.6 1.6e-07 31.3 2.6 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF2947 PF11163.8 KPA39540.1 - 0.044 13.6 0.3 0.083 12.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) DUF273 PF03314.14 KPA39540.1 - 0.049 13.2 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Glyco_hydro_43 PF04616.14 KPA39541.1 - 1.1e-30 107.0 13.5 2.7e-30 105.7 8.2 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 YchF-GTPase_C PF06071.13 KPA39542.1 - 3e-37 126.7 0.0 7.1e-37 125.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KPA39542.1 - 7.1e-22 77.6 0.0 2.2e-21 76.1 0.0 1.8 2 1 1 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPA39542.1 - 7.2e-08 32.1 0.0 1.5e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RR_TM4-6 PF06459.12 KPA39543.1 - 6.6 6.5 13.0 8.5 6.1 13.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4452 PF14618.6 KPA39545.1 - 5.3e-73 244.4 13.7 6.2e-73 244.2 13.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) LEA_3 PF03242.13 KPA39546.1 - 0.062 14.0 1.0 0.11 13.2 0.1 1.8 1 1 1 2 2 2 0 Late embryogenesis abundant protein Mito_carr PF00153.27 KPA39547.1 - 5.2e-46 154.5 7.6 8.5e-18 64.1 0.2 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KPA39547.1 - 0.033 13.4 0.6 0.09 11.9 0.1 2.0 2 0 0 2 2 2 0 Gammaproteobacterial serine protease DUF3337 PF11816.8 KPA39548.1 - 3.4e-55 186.5 0.0 9.6e-55 185.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KPA39548.1 - 3.1e-19 68.9 10.2 0.0017 19.2 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 KPA39548.1 - 0.0014 17.4 0.0 0.0043 15.8 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KPA39548.1 - 0.19 12.1 0.4 5.8 7.3 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 KPA39549.1 - 7.7e-46 156.1 0.0 1.3e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA39549.1 - 6.1e-23 81.3 0.0 5e-22 78.3 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KPA39549.1 - 1.7e-20 72.9 1.6 1.3e-19 70.2 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KPA39549.1 - 0.00031 20.8 0.0 0.00063 19.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Nop14 PF04147.12 KPA39549.1 - 0.027 12.7 9.1 0.035 12.3 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 KPA39549.1 - 1.1 9.0 13.0 2 8.2 13.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein KH_1 PF00013.29 KPA39550.1 - 7e-48 160.3 13.3 4.3e-17 61.7 0.9 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KPA39550.1 - 3.5e-12 46.0 1.5 0.015 15.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KPA39550.1 - 2.1e-08 33.9 7.2 0.095 12.6 0.4 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KPA39550.1 - 0.00057 19.8 0.0 1.2 9.2 0.0 3.1 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 KPA39550.1 - 0.0024 17.9 5.5 1.1 9.4 0.1 3.6 4 0 0 4 4 4 2 NusA-like KH domain DUF829 PF05705.14 KPA39551.1 - 2.6e-36 125.7 0.1 3.1e-36 125.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DSX_dimer PF08828.10 KPA39551.1 - 0.14 11.8 0.3 1.1 9.0 0.1 2.1 2 0 0 2 2 2 0 Doublesex dimerisation domain UDPGT PF00201.18 KPA39552.1 - 3.3e-09 36.1 0.0 4.6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Asp PF00026.23 KPA39553.1 - 3.9e-31 108.6 0.0 5.8e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KPA39553.1 - 0.00019 22.0 0.0 0.97 10.1 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KPA39553.1 - 0.0048 16.7 0.0 0.72 9.6 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal 6PF2K PF01591.18 KPA39554.1 - 3.2e-77 258.8 0.0 4.4e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KPA39554.1 - 2.2e-35 122.1 0.0 3.4e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KPA39554.1 - 4.9e-08 33.3 0.0 8.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KPA39554.1 - 0.043 13.3 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Borrelia_REV PF03978.13 KPA39555.1 - 0.11 12.4 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein LIM_bind PF01803.16 KPA39558.1 - 2e-75 253.4 0.0 2e-75 253.4 0.0 5.1 3 1 2 6 6 6 1 LIM-domain binding protein N-SET PF11764.8 KPA39560.1 - 3.3e-52 177.1 0.2 3.3e-52 177.1 0.2 2.8 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KPA39560.1 - 4.4e-25 87.1 0.7 1e-24 85.9 0.2 2.0 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated SET PF00856.28 KPA39560.1 - 5.5e-19 69.2 0.2 5.5e-19 69.2 0.2 3.1 2 2 0 2 2 2 1 SET domain Tropomyosin_1 PF12718.7 KPA39562.1 - 5.4e-54 182.2 31.9 6.9e-54 181.9 31.9 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KPA39562.1 - 2.9e-08 33.4 31.4 6.8e-05 22.4 13.6 2.9 1 1 2 3 3 3 3 Tropomyosin ADIP PF11559.8 KPA39562.1 - 5.5e-05 23.3 31.6 0.00041 20.5 8.7 3.0 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KPA39562.1 - 0.00025 21.4 33.1 0.27 11.4 15.0 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF724 PF05266.14 KPA39562.1 - 0.00025 20.9 23.9 0.03 14.2 8.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 KPA39562.1 - 0.00046 20.2 5.6 0.00046 20.2 5.6 2.8 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Alanine_zipper PF11839.8 KPA39562.1 - 0.00052 20.3 5.3 0.21 12.0 0.1 3.9 2 1 2 4 4 4 1 Alanine-zipper, major outer membrane lipoprotein MAD PF05557.13 KPA39562.1 - 0.00072 18.1 25.7 0.0016 16.9 12.1 2.0 1 1 1 2 2 2 1 Mitotic checkpoint protein FlaC_arch PF05377.11 KPA39562.1 - 0.00072 19.9 23.5 0.07 13.5 4.3 4.5 2 2 2 4 4 4 2 Flagella accessory protein C (FlaC) Spc7 PF08317.11 KPA39562.1 - 0.00078 18.4 33.4 0.019 13.8 15.2 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein CALCOCO1 PF07888.11 KPA39562.1 - 0.00081 18.4 31.3 0.013 14.4 16.8 2.0 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like NPV_P10 PF05531.12 KPA39562.1 - 0.00089 19.7 11.9 0.11 13.0 0.1 3.1 1 1 2 3 3 3 2 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.6 KPA39562.1 - 0.0012 19.2 30.6 0.011 16.2 12.2 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) Uso1_p115_C PF04871.13 KPA39562.1 - 0.0015 18.9 34.6 0.081 13.3 14.9 2.0 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region ERM PF00769.19 KPA39562.1 - 0.0019 18.0 35.6 0.029 14.2 17.0 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family T3SSipB PF16535.5 KPA39562.1 - 0.0037 17.8 18.0 0.22 12.0 9.9 2.6 1 1 1 2 2 2 2 Type III cell invasion protein SipB GAS PF13851.6 KPA39562.1 - 0.0038 16.6 33.7 0.11 11.8 22.4 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 KPA39562.1 - 0.007 16.9 39.6 0.11 13.0 23.4 2.2 1 1 1 2 2 2 1 Apg6 coiled-coil region Taxilin PF09728.9 KPA39562.1 - 0.0072 15.5 30.5 0.13 11.4 10.2 2.2 1 1 1 2 2 2 2 Myosin-like coiled-coil protein Lebercilin PF15619.6 KPA39562.1 - 0.0084 15.8 33.1 0.1 12.2 17.7 2.3 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.8 KPA39562.1 - 0.0091 15.3 29.6 0.51 9.6 8.4 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) CLZ PF16526.5 KPA39562.1 - 0.011 16.0 26.1 0.16 12.4 3.3 3.6 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TACC_C PF05010.14 KPA39562.1 - 0.012 15.4 24.7 0.12 12.1 23.3 2.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Surfac_D-trimer PF09006.11 KPA39562.1 - 0.014 15.3 5.2 0.021 14.7 0.0 3.3 4 0 0 4 4 2 0 Lung surfactant protein D coiled-coil trimerisation Laminin_II PF06009.12 KPA39562.1 - 0.015 15.3 5.4 0.015 15.3 5.4 2.3 1 1 1 2 2 2 0 Laminin Domain II CEP63 PF17045.5 KPA39562.1 - 0.017 15.1 26.4 0.02 14.8 26.4 1.0 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DUF5082 PF16888.5 KPA39562.1 - 0.018 15.3 22.6 0.56 10.5 7.6 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) BRE1 PF08647.11 KPA39562.1 - 0.018 15.1 30.9 0.42 10.7 8.1 2.7 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase TMF_TATA_bd PF12325.8 KPA39562.1 - 0.022 15.0 26.7 0.75 10.0 16.5 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.21 KPA39562.1 - 0.022 14.8 31.0 2.2 8.4 9.2 5.2 2 1 2 4 4 4 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 KPA39562.1 - 0.024 14.9 33.3 0.023 14.9 20.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Cep57_CLD_2 PF14197.6 KPA39562.1 - 0.035 14.2 31.3 3.6 7.7 1.0 4.0 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 KASH_CCD PF14662.6 KPA39562.1 - 0.036 13.9 33.5 0.081 12.7 25.9 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Seryl_tRNA_N PF02403.22 KPA39562.1 - 0.049 13.9 26.4 0.42 10.8 2.6 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 KPA39562.1 - 0.051 13.9 23.9 0.27 11.6 1.4 3.6 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 KPA39562.1 - 0.055 13.5 36.4 0.51 10.4 11.5 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.11 KPA39562.1 - 0.059 13.2 28.2 0.99 9.2 11.2 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 HMMR_N PF15905.5 KPA39562.1 - 0.061 12.8 32.0 0.11 11.9 32.0 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Rab5-bind PF09311.11 KPA39562.1 - 0.068 12.6 25.9 0.11 11.9 9.6 2.1 1 1 1 2 2 2 0 Rabaptin-like protein SOGA PF11365.8 KPA39562.1 - 0.08 14.1 25.6 1.5 10.0 10.1 3.3 1 1 2 3 3 3 0 Protein SOGA Fez1 PF06818.15 KPA39562.1 - 0.082 13.4 28.2 0.3 11.5 28.2 1.7 1 1 0 1 1 1 0 Fez1 DUF4618 PF15397.6 KPA39562.1 - 0.11 11.9 25.0 7.2 6.0 25.0 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) KELK PF15796.5 KPA39562.1 - 0.12 12.9 32.8 0.18 12.2 3.9 3.9 2 2 2 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KLRAQ PF10205.9 KPA39562.1 - 0.12 12.6 24.9 0.13 12.5 10.1 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DUF4686 PF15742.5 KPA39562.1 - 0.12 11.5 35.7 0.52 9.4 35.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Dynamitin PF04912.14 KPA39562.1 - 0.12 11.7 27.6 0.063 12.6 1.4 2.9 1 1 1 2 2 2 0 Dynamitin Atg14 PF10186.9 KPA39562.1 - 0.13 11.3 20.7 0.086 11.9 9.7 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 JAKMIP_CC3 PF16034.5 KPA39562.1 - 0.14 12.1 27.7 0.6 10.0 1.1 3.2 1 1 2 3 3 3 0 JAKMIP CC3 domain UPF0242 PF06785.11 KPA39562.1 - 0.14 12.2 33.2 0.84 9.7 12.4 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 KPA39562.1 - 0.18 10.4 24.5 0.21 10.2 9.1 2.1 1 1 1 2 2 2 0 AAA domain DUF2203 PF09969.9 KPA39562.1 - 0.18 12.5 18.1 1.8 9.3 5.2 2.3 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Syntaxin-6_N PF09177.11 KPA39562.1 - 0.19 12.3 20.3 4.7 7.8 2.5 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal CENP-H PF05837.12 KPA39562.1 - 0.2 12.1 26.0 0.69 10.3 7.8 2.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FlaF PF07309.11 KPA39562.1 - 0.2 11.6 8.0 0.058 13.4 2.3 2.4 1 1 1 2 2 2 0 Flagellar protein FlaF DUF3287 PF11690.8 KPA39562.1 - 0.21 11.3 8.0 0.53 10.0 0.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) DUF1664 PF07889.12 KPA39562.1 - 0.24 11.4 16.2 1.6 8.8 4.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 KPA39562.1 - 0.26 10.1 25.1 0.043 12.7 9.1 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain ZapB PF06005.12 KPA39562.1 - 0.29 11.6 40.7 0.86 10.1 3.0 4.3 1 1 2 3 3 3 0 Cell division protein ZapB EzrA PF06160.12 KPA39562.1 - 0.36 8.9 25.4 4.7 5.3 12.0 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA HOOK PF05622.12 KPA39562.1 - 0.42 8.7 31.3 0.63 8.1 29.5 1.8 1 1 0 1 1 1 0 HOOK protein CHDCT2 PF08074.11 KPA39562.1 - 0.42 10.8 11.4 0.048 13.8 4.3 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain TMF_DNA_bd PF12329.8 KPA39562.1 - 0.43 10.6 38.1 0.14 12.1 15.0 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4763 PF15960.5 KPA39562.1 - 0.44 9.8 20.5 0.72 9.1 5.9 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4763) DUF2730 PF10805.8 KPA39562.1 - 0.59 10.3 14.7 0.82 9.8 5.4 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF2730) WXG100 PF06013.12 KPA39562.1 - 0.67 10.2 16.3 2.7 8.3 0.4 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG CASP_C PF08172.12 KPA39562.1 - 0.68 9.2 22.8 0.31 10.4 2.5 2.4 1 1 1 2 2 2 0 CASP C terminal Prefoldin_2 PF01920.20 KPA39562.1 - 0.85 9.6 33.8 0.11 12.4 1.3 4.1 2 1 2 4 4 4 0 Prefoldin subunit HrpB7 PF09486.10 KPA39562.1 - 0.86 10.0 17.3 1.9 8.9 1.6 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF3584 PF12128.8 KPA39562.1 - 0.97 6.9 27.9 1.3 6.4 27.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ax_dynein_light PF10211.9 KPA39562.1 - 0.99 9.3 32.7 3.3 7.6 6.7 3.7 1 1 2 3 3 3 0 Axonemal dynein light chain DUF4201 PF13870.6 KPA39562.1 - 1.2 8.9 26.7 2.2e+02 1.5 26.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF745 PF05335.13 KPA39562.1 - 1.2 8.8 21.3 0.62 9.8 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF5320 PF17253.2 KPA39562.1 - 1.2 10.2 19.4 5.9 8.0 1.9 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5320) Sec34 PF04136.15 KPA39562.1 - 1.3 8.9 18.6 0.49 10.3 4.4 2.4 1 1 1 2 2 2 0 Sec34-like family PI3K_P85_iSH2 PF16454.5 KPA39562.1 - 1.4 8.5 27.8 1 9.0 21.0 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FUSC PF04632.12 KPA39562.1 - 1.5 7.3 6.2 1.6 7.2 6.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TANGO2 PF05742.12 KPA39562.1 - 1.6 8.7 8.9 1.4 8.9 7.4 1.7 1 1 1 2 2 2 0 Transport and Golgi organisation 2 DUF4407 PF14362.6 KPA39562.1 - 1.7 7.9 23.4 24 4.2 23.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 KPA39562.1 - 2.1 8.6 27.0 5.2 7.4 2.3 4.1 1 1 4 5 5 5 0 Haemolysin XhlA Fib_alpha PF08702.10 KPA39562.1 - 2.2 8.5 18.7 1.7 8.8 4.6 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SHE3 PF17078.5 KPA39562.1 - 2.4 7.8 27.1 0.24 11.1 2.1 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 FapA PF03961.13 KPA39562.1 - 2.5 6.6 25.9 0.24 9.9 8.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A NABP PF07990.12 KPA39562.1 - 2.5 7.6 7.5 2.8 7.4 7.5 1.2 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Fungal_TACC PF12709.7 KPA39562.1 - 2.8 8.4 29.1 1.9 9.0 4.0 4.0 1 1 3 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Phage_GPO PF05929.11 KPA39562.1 - 3 7.4 21.3 4.2 6.9 13.7 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase HAP1_N PF04849.13 KPA39562.1 - 3.1 6.9 32.0 10 5.2 32.0 2.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region BST2 PF16716.5 KPA39562.1 - 3.8 8.2 30.0 0.066 13.8 4.5 3.6 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Lectin_N PF03954.14 KPA39562.1 - 4.1 7.2 18.2 3.4 7.4 0.7 3.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Rx_N PF18052.1 KPA39562.1 - 4.1 7.7 14.2 1.2 9.5 6.6 2.8 1 1 2 3 3 3 0 Rx N-terminal domain DUF948 PF06103.11 KPA39562.1 - 4.9 7.5 13.7 63 3.9 4.7 3.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TolA_bind_tri PF16331.5 KPA39562.1 - 5 7.3 26.4 0.51 10.4 0.6 3.9 2 1 2 4 4 4 0 TolA binding protein trimerisation DUF4472 PF14739.6 KPA39562.1 - 5.2 7.9 27.6 39 5.0 7.7 2.9 1 1 1 2 2 1 0 Domain of unknown function (DUF4472) DUF4795 PF16043.5 KPA39562.1 - 5.4 6.6 27.4 75 2.8 27.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) CR6_interact PF10147.9 KPA39562.1 - 6.2 6.5 22.4 0.16 11.7 8.7 2.1 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TMPIT PF07851.13 KPA39562.1 - 6.8 5.8 21.5 4.5 6.4 3.4 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF16 PF01519.16 KPA39562.1 - 6.9 7.2 24.7 13 6.3 4.5 3.0 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF812 PF05667.11 KPA39562.1 - 7.1 5.4 30.3 20 3.9 30.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) SlyX PF04102.12 KPA39562.1 - 7.2 7.3 25.8 1.5 9.5 4.4 3.8 1 1 2 4 4 4 0 SlyX DUF5595 PF18077.1 KPA39562.1 - 7.3 6.8 24.6 2.8 8.1 5.1 4.0 2 2 1 4 4 4 0 Domain of unknown function (DUF5595) TRAF_BIRC3_bd PF16673.5 KPA39562.1 - 7.3 6.5 17.9 6.2 6.7 0.9 4.1 1 1 4 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain YabA PF06156.13 KPA39562.1 - 7.6 7.2 26.2 12 6.5 1.1 3.2 1 1 1 2 2 2 0 Initiation control protein YabA GIT_CC PF16559.5 KPA39562.1 - 7.6 6.5 25.7 2.9 7.8 3.3 4.6 1 1 4 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor HAUS-augmin3 PF14932.6 KPA39562.1 - 7.8 6.0 30.9 8 6.0 5.6 2.4 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 LPP PF04728.13 KPA39562.1 - 8.4 6.9 16.1 46 4.5 0.5 4.4 2 2 1 3 3 3 0 Lipoprotein leucine-zipper Nup54 PF13874.6 KPA39562.1 - 8.6 6.5 23.5 4.8 7.3 6.2 2.8 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF4482 PF14818.6 KPA39562.1 - 8.9 7.2 25.5 1 10.2 3.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4482) OmpH PF03938.14 KPA39562.1 - 8.9 6.7 35.0 1.8e+04 -8.7 35.0 2.9 1 1 0 1 1 0 0 Outer membrane protein (OmpH-like) Nup88 PF10168.9 KPA39562.1 - 9.5 3.9 21.7 12 3.6 21.7 1.1 1 0 0 1 1 1 0 Nuclear pore component Nop25 PF09805.9 KPA39563.1 - 1.8e-42 145.1 19.7 1.8e-42 145.1 19.7 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) EIIBC-GUT_N PF03612.14 KPA39563.1 - 4.9 6.9 15.3 0.61 9.8 5.2 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus ATP-synt_S1 PF05827.12 KPA39564.1 - 6.3e-05 22.8 0.1 0.00015 21.6 0.1 1.6 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF243 PF03103.17 KPA39564.1 - 0.019 15.2 1.0 0.043 14.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF243) Med6 PF04934.14 KPA39564.1 - 0.053 13.3 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 MED6 mediator sub complex component GPHR_N PF12537.8 KPA39564.1 - 0.063 13.4 0.2 0.21 11.7 0.2 1.9 1 1 1 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Trm112p PF03966.16 KPA39565.1 - 1.5e-16 60.7 0.1 1.8e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Pro_isomerase PF00160.21 KPA39566.1 - 1.4e-47 161.9 0.4 1.8e-47 161.5 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 KPA39567.1 - 1.3e-17 64.4 1.9 1.5e-15 57.7 1.9 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_M19 PF01244.21 KPA39568.1 - 2.9e-102 342.1 0.0 3.5e-102 341.8 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) tRNA-synt_1b PF00579.25 KPA39569.1 - 2.6e-63 214.1 0.0 3.3e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PAN_3 PF08277.12 KPA39570.1 - 0.16 11.8 0.3 0.16 11.8 0.3 2.2 2 0 0 2 2 2 0 PAN-like domain EST1 PF10374.9 KPA39570.1 - 0.34 11.5 9.5 4 8.1 9.5 2.3 1 1 0 1 1 1 0 Telomerase activating protein Est1 Suf PF05843.14 KPA39570.1 - 0.56 10.1 7.0 0.75 9.7 7.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2052 PF09747.9 KPA39570.1 - 0.67 10.0 3.3 0.89 9.7 3.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Apt1 PF10351.9 KPA39570.1 - 6.3 5.5 10.6 7.9 5.2 10.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PHA-1 PF06542.11 KPA39571.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Regulator protein PHA-1 RhoGAP PF00620.27 KPA39572.1 - 1.9e-15 57.0 0.0 4.7e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 KPA39572.1 - 7.8e-12 45.1 0.0 2e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KPA39572.1 - 5.9e-11 42.5 0.0 2.3e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Adaptin_N PF01602.20 KPA39573.1 - 1.7e-83 281.0 0.0 2.2e-83 280.6 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KPA39573.1 - 4.8e-05 23.4 0.1 0.01 15.9 0.0 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KPA39573.1 - 0.89 10.1 3.3 82 3.9 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat Polyketide_cyc PF03364.20 KPA39574.1 - 1.3e-24 86.9 0.0 2.2e-24 86.1 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TPR_11 PF13414.6 KPA39576.1 - 4.2e-10 39.1 0.0 0.00042 19.9 0.2 3.6 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 KPA39576.1 - 5.9e-09 36.3 1.5 9.6e-05 22.8 0.0 4.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPA39576.1 - 4.8e-07 29.4 0.2 0.00075 19.4 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPA39576.1 - 1.4e-05 25.5 4.6 0.045 14.6 0.1 5.4 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KPA39576.1 - 0.00036 20.2 0.0 0.049 13.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KPA39576.1 - 0.00062 20.0 0.1 0.08 13.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KPA39576.1 - 0.0016 18.5 0.0 0.0057 16.8 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.6 KPA39576.1 - 0.002 18.4 0.4 0.37 11.2 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF627 PF04781.12 KPA39576.1 - 0.0024 17.9 0.1 0.0088 16.0 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF627) TPR_16 PF13432.6 KPA39576.1 - 0.0059 17.2 0.5 0.054 14.1 0.0 2.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA39576.1 - 0.0099 16.0 0.0 0.67 10.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.10 KPA39576.1 - 0.018 14.1 0.2 0.026 13.5 0.2 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.6 KPA39576.1 - 0.033 14.5 0.7 3.3 8.1 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPA39576.1 - 0.05 14.3 0.1 2.2 9.1 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KPA39576.1 - 0.085 12.9 0.1 6.6 6.9 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Methyltransf_12 PF08242.12 KPA39577.1 - 2.4e-15 57.1 0.0 6e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA39577.1 - 3.1e-15 56.7 0.0 6.6e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA39577.1 - 4.9e-12 46.3 0.0 1.1e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA39577.1 - 8.2e-12 45.3 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA39577.1 - 2.2e-07 30.8 0.0 3.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA39577.1 - 1e-05 25.0 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KPA39577.1 - 0.00021 22.2 0.0 0.00067 20.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 KPA39577.1 - 0.0005 20.0 0.0 0.0032 17.4 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KPA39577.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 KPA39577.1 - 0.012 14.8 0.0 2.5 7.2 0.0 2.2 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.9 KPA39577.1 - 0.061 13.1 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 KPA39577.1 - 0.11 12.2 0.1 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Nup_retrotrp_bd PF10599.9 KPA39577.1 - 0.13 12.9 1.0 0.54 11.0 0.0 2.6 3 0 0 3 3 3 0 Retro-transposon transporting motif Pkinase PF00069.25 KPA39578.1 - 2.6e-05 23.7 0.0 0.0094 15.3 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Ank_2 PF12796.7 KPA39579.1 - 1.8e-23 82.9 0.0 9.5e-13 48.5 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KPA39579.1 - 6.8e-09 35.8 0.3 0.0066 16.9 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KPA39579.1 - 1e-08 34.7 0.0 0.06 13.9 0.0 4.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KPA39579.1 - 2.6e-08 34.3 0.1 1.6e-07 31.7 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA39579.1 - 7.2e-05 23.0 0.1 0.19 12.1 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Cyclin_N PF00134.23 KPA39580.1 - 1.4e-10 41.0 0.1 3.2e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KPA39580.1 - 0.14 12.3 0.2 0.28 11.3 0.2 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat WD40 PF00400.32 KPA39581.1 - 5.8e-40 134.5 24.1 2.9e-09 37.4 1.5 7.6 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA39581.1 - 1.3e-15 57.4 2.7 0.045 14.1 0.2 5.7 3 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KPA39581.1 - 2.4e-13 49.4 2.6 5.6e-13 48.2 2.6 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.6 KPA39581.1 - 0.0029 17.0 0.1 0.15 11.4 0.0 2.5 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KPA39581.1 - 0.0033 16.4 0.0 10 5.0 0.0 4.6 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KPA39581.1 - 0.011 15.0 0.0 4.4 6.6 0.0 3.4 4 0 0 4 4 4 0 WD40-like domain Pkinase PF00069.25 KPA39582.1 - 7.1e-68 228.8 0.0 9e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA39582.1 - 4.5e-30 104.8 0.0 6.1e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPA39582.1 - 0.0011 18.0 0.2 0.0017 17.4 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 KPA39582.1 - 0.0018 19.0 0.0 0.0048 17.6 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KPA39582.1 - 0.015 14.6 0.1 0.074 12.4 0.0 1.9 1 1 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KPA39582.1 - 0.018 13.9 0.0 0.032 13.0 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KPA39582.1 - 0.03 14.0 0.3 2 8.0 0.1 2.6 1 1 2 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 CDH-cyt PF16010.5 KPA39583.1 - 3e-18 66.2 0.0 5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 KPA39583.1 - 0.00055 19.7 1.0 0.00055 19.7 1.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) ATP_sub_h PF10775.9 KPA39584.1 - 6e-25 87.0 0.1 1.3e-24 86.0 0.1 1.6 1 0 0 1 1 1 1 ATP synthase complex subunit h Pkinase PF00069.25 KPA39585.1 - 1.9e-69 234.0 0.0 2.5e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA39585.1 - 1.1e-31 110.0 0.0 1.5e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KPA39585.1 - 1.5e-13 51.2 0.3 1.5e-13 51.2 0.3 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KPA39585.1 - 2e-09 37.2 0.1 6.9e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 KPA39585.1 - 2.7e-09 37.3 0.0 3.1e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 KPA39585.1 - 0.0014 17.7 0.1 0.0033 16.4 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KPA39585.1 - 0.014 14.8 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KPA39585.1 - 0.034 13.8 0.3 2.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KPA39585.1 - 0.073 12.6 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SUZ PF12752.7 KPA39586.1 - 2.5e-06 28.2 3.6 2.5e-06 28.2 3.6 2.7 2 1 0 2 2 2 1 SUZ domain Fe_hyd_lg_C PF02906.14 KPA39587.1 - 6.8e-53 179.8 0.0 1.8e-52 178.5 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain CarboxypepD_reg PF13620.6 KPA39587.1 - 0.11 12.7 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF987 PF06174.11 KPA39588.1 - 0.17 11.8 0.1 0.82 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF987) zf-H2C2_2 PF13465.6 KPA39589.1 - 2.3e-06 27.8 11.2 5e-06 26.7 1.3 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KPA39589.1 - 9.3e-06 25.8 0.5 9.3e-06 25.8 0.5 3.4 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KPA39589.1 - 4.4e-05 23.4 4.9 0.01 15.8 0.0 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KPA39589.1 - 0.00021 21.9 4.6 0.0038 18.0 0.4 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 KPA39589.1 - 0.00072 20.1 5.7 0.24 12.1 0.0 2.9 2 1 0 2 2 2 2 FOXP coiled-coil domain DUF3113 PF11310.8 KPA39589.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) zf-C2H2_11 PF16622.5 KPA39589.1 - 0.091 12.5 1.3 0.54 10.1 0.1 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KPA39589.1 - 0.16 12.3 1.5 2.5 8.5 0.3 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KPA39589.1 - 0.18 11.6 2.8 0.6 9.9 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Sina PF03145.16 KPA39589.1 - 1 9.3 7.6 2.8 7.8 2.2 2.3 1 1 1 2 2 2 0 Seven in absentia protein family DAHP_synth_1 PF00793.20 KPA39590.1 - 6.1e-102 340.2 0.1 7.6e-102 339.9 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2070 PF09843.9 KPA39591.1 - 0.14 10.4 0.9 0.17 10.2 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) BPD_transp_1 PF00528.22 KPA39591.1 - 0.73 9.5 10.2 7.3 6.3 10.2 1.9 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component PVL_ORF50 PF07768.11 KPA39594.1 - 4.5 7.6 7.1 0.35 11.2 1.1 2.1 2 0 0 2 2 2 0 PVL ORF-50-like family ACP_syn_III PF08545.10 KPA39595.1 - 0.1 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Rhomboid PF01694.22 KPA39596.1 - 3.8e-19 69.2 6.6 3.8e-19 69.2 6.6 1.8 2 0 0 2 2 2 1 Rhomboid family NUMOD3 PF07460.11 KPA39596.1 - 0.039 14.2 0.1 0.09 13.0 0.1 1.6 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) NADH-u_ox-rdase PF10785.9 KPA39596.1 - 0.17 12.6 0.7 2 9.2 0.0 2.6 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF4647 PF15504.6 KPA39596.1 - 0.29 10.2 3.2 0.42 9.7 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Borrelia_P83 PF05262.11 KPA39596.1 - 1.1 7.6 9.1 1.5 7.3 9.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4078 PF13300.6 KPA39596.1 - 8.1 6.8 9.6 9.7 6.6 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) SIR2 PF02146.17 KPA39597.1 - 2.2e-24 86.3 0.0 6.6e-24 84.8 0.0 1.7 1 1 0 1 1 1 1 Sir2 family TraF_2 PF13729.6 KPA39597.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Acyl-thio_N PF12590.8 KPA39597.1 - 0.76 10.4 5.2 2.2 8.9 5.2 1.8 1 0 0 1 1 1 0 Acyl-ATP thioesterase Rad60-SLD PF11976.8 KPA39598.1 - 2.6e-16 59.2 0.1 5.1e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KPA39598.1 - 0.0018 18.0 0.0 0.0045 16.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family SHOCT PF09851.9 KPA39598.1 - 0.074 12.8 3.4 0.21 11.4 3.4 1.8 1 0 0 1 1 1 0 Short C-terminal domain LSM PF01423.22 KPA39599.1 - 2.5e-20 71.9 0.1 2.8e-20 71.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KPA39599.1 - 2.9e-05 24.1 0.1 3.6e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KPA39599.1 - 0.0011 19.0 0.1 0.0013 18.8 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Hfq PF17209.3 KPA39599.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Methyltransf_11 PF08241.12 KPA39600.1 - 9e-12 45.5 0.0 1.5e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA39600.1 - 2.1e-10 41.1 0.0 3.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA39600.1 - 1.7e-05 24.6 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA39600.1 - 0.00026 20.9 0.0 0.00045 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA39600.1 - 0.0006 20.5 0.0 0.0012 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA39600.1 - 0.00069 19.0 0.0 0.0015 17.9 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KPA39600.1 - 0.011 15.9 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase AUDH_Cupin PF18637.1 KPA39600.1 - 0.026 14.5 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain DREV PF05219.12 KPA39600.1 - 0.073 12.2 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase DUF1180 PF06679.12 KPA39601.1 - 0.15 12.4 0.6 18 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Cys_Met_Meta_PP PF01053.20 KPA39603.1 - 1.1e-62 211.7 0.0 2.4e-62 210.7 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KPA39603.1 - 0.052 12.5 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Polysacc_deac_1 PF01522.21 KPA39605.1 - 4.8e-21 74.9 0.0 7.7e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 KPA39605.1 - 0.0021 17.3 0.0 0.0041 16.3 0.0 1.5 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase pPIWI_RE_REase PF18154.1 KPA39605.1 - 0.01 15.8 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 REase associating with pPIWI_RE SIS PF01380.22 KPA39605.1 - 0.034 14.0 0.1 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 SIS domain DUF3822 PF12864.7 KPA39605.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) Terpene_synth_C PF03936.16 KPA39606.1 - 3.6e-05 23.2 0.0 6.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain WD40 PF00400.32 KPA39608.1 - 2.4e-16 59.8 9.8 0.01 16.7 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA39608.1 - 7.1e-07 29.4 0.5 0.0027 18.0 0.2 4.1 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA39608.1 - 3.9e-06 25.8 3.2 7.2e-05 21.6 1.0 3.2 2 2 1 3 3 3 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 KPA39608.1 - 0.16 11.0 0.2 0.29 10.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) PALB2_WD40 PF16756.5 KPA39608.1 - 0.16 10.8 0.6 0.88 8.4 0.2 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain HA2 PF04408.23 KPA39609.1 - 2.9e-22 79.0 0.0 2.9e-22 79.0 0.0 3.3 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KPA39609.1 - 1.4e-18 67.0 0.0 3.8e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KPA39609.1 - 1.2e-13 51.3 0.0 3.1e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPA39609.1 - 7.2e-08 32.4 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KPA39609.1 - 2.1e-05 24.8 0.1 5.5e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPA39609.1 - 0.00038 20.2 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPA39609.1 - 0.0013 19.1 0.1 0.0031 17.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KPA39609.1 - 0.0018 17.6 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 KPA39609.1 - 0.0039 16.8 0.4 0.0088 15.7 0.4 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 KPA39609.1 - 0.01 15.9 0.0 0.83 9.6 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 KPA39609.1 - 0.014 14.5 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KPA39609.1 - 0.016 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 KPA39609.1 - 0.024 14.6 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_33 PF13671.6 KPA39609.1 - 0.03 14.5 0.8 0.094 12.9 0.0 2.4 2 0 0 2 2 1 0 AAA domain Microtub_bd PF16796.5 KPA39609.1 - 0.06 13.3 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding AAA_16 PF13191.6 KPA39609.1 - 0.089 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KPA39609.1 - 0.13 12.8 0.0 0.64 10.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Acylphosphatase PF00708.18 KPA39610.1 - 9.4e-24 83.6 1.3 1e-23 83.5 1.3 1.0 1 0 0 1 1 1 1 Acylphosphatase Hep_59 PF07052.11 KPA39611.1 - 3.7e-09 37.3 0.1 3.7e-09 37.3 0.1 2.8 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 LssY_C PF14067.6 KPA39613.1 - 0.13 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 LssY C-terminus Het-C PF07217.11 KPA39614.1 - 1.5e-145 485.9 0.2 1.8e-109 366.8 0.0 2.0 2 0 0 2 2 2 2 Heterokaryon incompatibility protein Het-C Zn_dep_PLPC PF00882.18 KPA39614.1 - 0.0025 17.8 0.0 0.0053 16.8 0.0 1.5 1 0 0 1 1 1 1 Zinc dependent phospholipase C Glyco_trans_1_2 PF13524.6 KPA39615.1 - 0.026 14.9 0.7 4.1 7.9 0.0 3.1 1 1 2 3 3 3 0 Glycosyl transferases group 1 CBM_14 PF01607.24 KPA39615.1 - 0.036 14.2 21.0 14 6.0 0.5 5.2 2 2 3 5 5 5 0 Chitin binding Peritrophin-A domain Orthopox_B11R PF07033.11 KPA39615.1 - 3.3 7.6 11.5 10 6.0 0.4 3.3 3 0 0 3 3 3 0 Orthopoxvirus B11R protein Sec62 PF03839.16 KPA39615.1 - 9 5.7 10.1 13 5.2 10.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Sulfatase PF00884.23 KPA39618.1 - 8.9e-20 71.3 0.3 1.7e-19 70.4 0.3 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPA39618.1 - 4.8e-06 26.4 0.1 7.6e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KPA39618.1 - 0.017 13.8 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Mucin PF01456.17 KPA39619.1 - 0.00033 20.6 19.0 0.0005 20.1 19.0 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein SWI-SNF_Ssr4 PF08549.10 KPA39619.1 - 0.76 8.3 6.9 0.87 8.2 6.9 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF966 PF06136.13 KPA39619.1 - 0.81 9.3 6.1 0.98 9.1 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Ank_2 PF12796.7 KPA39620.1 - 2.5e-16 60.1 0.0 7e-08 32.9 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA39620.1 - 2.9e-09 37.3 0.0 0.0054 17.3 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) HET PF06985.11 KPA39620.1 - 5.7e-06 26.8 0.0 1.4e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.6 KPA39620.1 - 6.5e-06 26.1 0.0 11 6.9 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 KPA39620.1 - 4.5e-05 23.7 0.0 0.17 12.4 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KPA39620.1 - 0.00042 20.5 0.1 0.18 12.1 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) EB PF01683.18 KPA39621.1 - 4.5e-07 30.1 190.8 0.027 14.8 0.0 19.3 8 5 9 17 17 17 11 EB module Stig1 PF04885.13 KPA39621.1 - 0.00025 21.5 6.4 0.00025 21.5 6.4 11.3 6 3 4 12 12 12 6 Stigma-specific protein, Stig1 Aspzincin_M35 PF14521.6 KPA39622.1 - 0.01 16.3 3.4 0.059 13.9 3.4 2.2 1 1 0 1 1 1 0 Lysine-specific metallo-endopeptidase Kelch_5 PF13854.6 KPA39624.1 - 1.6e-12 47.1 8.6 2e-08 34.0 0.2 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 KPA39624.1 - 1.1e-07 31.7 11.2 0.0064 16.5 0.2 5.4 6 1 0 6 6 6 3 Galactose oxidase, central domain SKG6 PF08693.10 KPA39624.1 - 2.9e-05 23.4 0.2 5.7e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_6 PF13964.6 KPA39624.1 - 4.8e-05 23.5 11.8 4.8 7.6 0.2 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 KPA39624.1 - 5.1e-05 22.8 13.8 1.4 8.6 0.2 6.2 6 0 0 6 6 6 2 Kelch motif Rax2 PF12768.7 KPA39624.1 - 0.017 14.6 0.0 0.11 11.9 0.0 2.2 3 0 0 3 3 3 0 Cortical protein marker for cell polarity Kelch_2 PF07646.15 KPA39624.1 - 0.035 14.1 9.3 6.1 7.0 0.0 5.8 5 1 0 5 5 5 0 Kelch motif Kelch_3 PF13415.6 KPA39624.1 - 0.12 12.7 20.8 0.67 10.3 0.3 5.9 6 0 0 6 6 6 0 Galactose oxidase, central domain NICE-1 PF15845.5 KPA39624.1 - 0.16 12.8 3.6 0.43 11.4 3.6 1.7 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family Syndecan PF01034.20 KPA39624.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DAO PF01266.24 KPA39625.1 - 1.2e-29 104.0 0.0 1.5e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPA39625.1 - 3.2e-08 33.1 0.4 3.2e-06 26.5 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KPA39625.1 - 1.5e-06 27.7 0.1 6.3e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPA39625.1 - 1.6e-06 27.8 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPA39625.1 - 4.8e-06 26.0 0.0 1.2e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KPA39625.1 - 1.2e-05 24.7 0.2 2.7e-05 23.6 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA39625.1 - 1.9e-05 24.1 0.0 0.00016 21.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA39625.1 - 1.9e-05 23.9 0.5 0.0013 17.9 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KPA39625.1 - 3.3e-05 22.8 0.4 0.00021 20.1 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KPA39625.1 - 0.00023 21.3 0.1 0.00069 19.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPA39625.1 - 0.019 15.5 0.1 0.042 14.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA39625.1 - 0.022 13.9 0.1 6.9 5.7 0.1 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KPA39625.1 - 0.053 12.8 0.1 0.093 12.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KPA39625.1 - 0.087 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KPA39625.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding PAD PF03068.15 KPA39626.1 - 2.3e-116 389.0 0.1 4e-116 388.2 0.1 1.3 1 1 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.10 KPA39626.1 - 0.1 12.2 0.3 0.39 10.4 0.3 2.0 1 1 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain adh_short PF00106.25 KPA39627.1 - 2e-17 63.3 0.0 2.5e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA39627.1 - 1.8e-12 47.3 0.0 2.5e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA39627.1 - 5.1e-08 33.0 0.0 6.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA39627.1 - 0.03 13.5 0.0 0.045 12.9 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 KPA39627.1 - 0.066 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SF3b1 PF08920.10 KPA39627.1 - 0.069 13.7 0.1 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 Glyco_tran_WecB PF03808.13 KPA39627.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family F-box PF00646.33 KPA39628.1 - 4.9e-07 29.5 0.9 4.9e-07 29.5 0.9 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KPA39628.1 - 0.0014 18.5 0.9 0.0045 16.9 0.6 2.1 2 0 0 2 2 2 1 F-box-like ABC_tran PF00005.27 KPA39629.1 - 2.1e-52 177.3 0.0 2e-30 106.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KPA39629.1 - 7.4e-35 120.9 24.1 2.1e-25 89.9 8.2 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KPA39629.1 - 1.5e-09 37.6 0.1 0.00015 21.3 0.0 4.2 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KPA39629.1 - 0.00015 21.8 0.0 0.068 13.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KPA39629.1 - 0.00024 21.5 0.3 0.2 12.0 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KPA39629.1 - 0.0006 19.8 0.2 0.49 10.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KPA39629.1 - 0.0021 17.7 0.5 1.5 8.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KPA39629.1 - 0.004 17.4 1.3 5.5 7.3 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KPA39629.1 - 0.0056 16.5 0.3 9.6 5.9 0.1 3.5 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KPA39629.1 - 0.0057 15.7 0.1 0.53 9.3 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_25 PF13481.6 KPA39629.1 - 0.011 15.4 0.0 0.97 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KPA39629.1 - 0.02 15.4 3.9 0.26 11.8 0.2 2.7 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.9 KPA39629.1 - 0.026 13.8 0.3 0.35 10.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 KPA39629.1 - 0.028 14.1 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 KPA39629.1 - 0.04 14.0 3.7 0.5 10.4 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain DUF3290 PF11694.8 KPA39629.1 - 0.05 13.6 0.1 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) MeaB PF03308.16 KPA39629.1 - 0.084 11.8 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KPA39629.1 - 0.11 11.8 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 KPA39629.1 - 0.11 12.8 0.2 30 5.0 0.1 3.4 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 KPA39629.1 - 0.13 11.8 0.1 13 5.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KPA39629.1 - 0.22 11.2 0.9 14 5.4 0.1 2.8 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 KPA39629.1 - 0.85 9.7 2.7 28 4.8 0.1 3.0 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cmc1 PF08583.10 KPA39630.1 - 0.087 12.9 2.6 0.18 11.8 2.6 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4023 PF13215.6 KPA39630.1 - 0.16 12.0 0.5 0.48 10.5 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) MIase PF02426.16 KPA39630.1 - 0.83 9.9 0.1 0.83 9.9 0.1 3.1 2 1 1 3 3 3 0 Muconolactone delta-isomerase DUF3128 PF11326.8 KPA39630.1 - 4.3 7.8 10.2 3.6e+02 1.6 9.8 3.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Ribosomal_S17_N PF16205.5 KPA39631.1 - 3.5e-33 113.8 0.5 7.5e-33 112.7 0.5 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KPA39631.1 - 4.9e-26 90.6 1.1 1.1e-25 89.5 1.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.6 KPA39632.1 - 6.1e-190 633.7 105.8 6e-122 408.7 38.3 5.2 1 1 3 4 4 4 4 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KPA39632.1 - 1.6e-126 421.4 4.1 1.6e-126 421.4 4.1 2.6 3 0 0 3 3 3 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KPA39632.1 - 7.9e-22 77.1 1.7 1.5e-21 76.2 1.7 1.5 1 0 0 1 1 1 1 Spc7_C2 Glyco_trans_1_2 PF13524.6 KPA39632.1 - 0.57 10.6 0.0 0.57 10.6 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 Atg14 PF10186.9 KPA39633.1 - 6e-73 245.7 0.1 7.8e-73 245.3 0.1 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Sipho_Gp157 PF05565.11 KPA39633.1 - 0.016 15.2 4.8 0.026 14.5 4.8 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 Leu_zip PF15294.6 KPA39633.1 - 0.15 11.6 4.8 0.23 10.9 4.8 1.3 1 0 0 1 1 1 0 Leucine zipper Mod_r PF07200.13 KPA39633.1 - 0.18 11.9 4.9 0.3 11.2 4.9 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein HD_2 PF12917.7 KPA39633.1 - 0.21 11.3 1.1 0.4 10.4 1.1 1.4 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Spc7 PF08317.11 KPA39633.1 - 0.48 9.3 5.6 0.67 8.8 5.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Tho2 PF11262.8 KPA39633.1 - 1.4 8.0 4.9 2.2 7.4 4.9 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 KPA39633.1 - 2.5 7.4 7.4 3.6 6.9 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_S30 PF04758.14 KPA39634.1 - 0.11 12.7 0.3 0.34 11.2 0.3 1.7 1 0 0 1 1 1 0 Ribosomal protein S30 DUF488 PF04343.13 KPA39634.1 - 0.31 11.6 4.5 0.24 12.0 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF488 DUF3807 PF12720.7 KPA39635.1 - 4.7e-44 150.8 2.6 5.6e-44 150.6 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) DUF2951 PF11166.8 KPA39635.1 - 0.14 12.4 0.4 0.26 11.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Pkinase PF00069.25 KPA39636.1 - 3e-64 216.9 0.1 3.6e-64 216.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA39636.1 - 3.7e-18 65.8 0.0 5.2e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPA39636.1 - 3.9e-09 36.8 0.0 3.3e-06 27.2 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KPA39636.1 - 0.0071 15.2 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KPA39636.1 - 0.02 14.2 0.0 0.04 13.2 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 KPA39636.1 - 0.022 14.1 0.1 0.041 13.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KPA39636.1 - 0.024 14.2 1.1 0.045 13.3 0.1 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Aconitase_B_N PF11791.8 KPA39636.1 - 0.14 12.2 0.0 0.45 10.6 0.0 1.7 2 0 0 2 2 2 0 Aconitate B N-terminal domain Scm3 PF10384.9 KPA39637.1 - 9.3e-21 73.3 1.0 1.7e-20 72.5 0.0 2.0 2 0 0 2 2 2 1 Centromere protein Scm3 APG6 PF04111.12 KPA39638.1 - 1.8e-70 236.6 0.0 2.7e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KPA39638.1 - 7.2e-34 117.2 19.2 9.8e-34 116.7 19.2 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Rpr2 PF04032.16 KPA39638.1 - 0.019 15.2 0.0 0.046 14.0 0.0 1.7 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain UPF0242 PF06785.11 KPA39638.1 - 0.058 13.5 14.3 0.1 12.7 14.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 KPA39638.1 - 0.21 11.4 15.4 0.31 10.8 15.4 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF1732 PF08340.11 KPA39638.1 - 0.23 11.4 3.7 0.48 10.4 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) Macoilin PF09726.9 KPA39638.1 - 0.52 8.8 16.6 0.79 8.2 16.6 1.2 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 KPA39638.1 - 0.79 7.6 6.9 1.1 7.1 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 KPA39638.1 - 1.6 8.0 5.6 2.6 7.3 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 KPA39638.1 - 2.3 8.5 15.3 3.5 7.9 13.4 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding KELK PF15796.5 KPA39638.1 - 3.2 8.3 23.0 3.6 8.1 20.6 2.1 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2514 PF10721.9 KPA39638.1 - 4 7.5 7.3 14 5.7 7.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) FapA PF03961.13 KPA39638.1 - 5 5.6 6.2 7 5.1 6.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ERM PF00769.19 KPA39638.1 - 5.4 6.7 23.8 0.8 9.5 18.8 1.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family AAA PF00004.29 KPA39639.1 - 9e-13 48.8 0.0 2.2e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPA39639.1 - 0.0011 19.4 0.1 0.0028 18.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KPA39639.1 - 0.021 14.8 0.0 0.08 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CPT PF07931.12 KPA39639.1 - 0.037 13.9 0.0 0.094 12.6 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 KPA39639.1 - 0.068 13.4 0.1 0.37 11.1 0.1 1.9 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KPA39639.1 - 0.15 12.2 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KPA39639.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prefoldin_3 PF13758.6 KPA39640.1 - 2.6e-27 94.8 0.7 2.6e-27 94.8 0.7 2.3 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 KPA39640.1 - 4.7e-24 85.0 0.4 4.7e-24 85.0 0.4 4.8 4 2 1 5 5 5 1 Domain of unknown function (DUF3835) Lzipper-MIP1 PF14389.6 KPA39640.1 - 0.034 14.4 1.4 1.8 8.9 0.1 3.1 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Prefoldin PF02996.17 KPA39640.1 - 0.04 13.8 1.5 10 6.0 0.1 2.8 2 0 0 2 2 2 0 Prefoldin subunit CLZ PF16526.5 KPA39640.1 - 0.11 12.9 2.9 4.7 7.6 0.2 3.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Use1 PF09753.9 KPA39640.1 - 0.48 10.1 5.8 0.12 12.1 1.0 2.2 2 0 0 2 2 2 0 Membrane fusion protein Use1 DUF5082 PF16888.5 KPA39640.1 - 1.2 9.4 5.0 6.8 7.0 5.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) CCDC-167 PF15188.6 KPA39640.1 - 1.4 9.4 5.7 7.1 7.0 0.1 3.5 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.20 KPA39640.1 - 4 7.4 11.3 2 8.4 0.1 3.3 4 0 0 4 4 4 0 Prefoldin subunit GFA PF04828.14 KPA39641.1 - 3.9e-14 52.8 9.3 6.5e-08 32.8 0.8 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 KPA39641.1 - 7.5 6.6 13.2 4.3 7.3 0.9 4.1 4 0 0 4 4 4 0 Nudix N-terminal Mur_ligase_C PF02875.21 KPA39642.1 - 0.0072 16.5 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 KPA39642.1 - 0.066 13.2 0.0 0.31 11.0 0.0 2.0 1 1 0 1 1 1 0 Mur ligase middle domain Mur_ligase_C PF02875.21 KPA39643.1 - 0.035 14.4 0.0 0.093 13.0 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Pectate_lyase_3 PF12708.7 KPA39644.1 - 1.7e-72 243.7 5.8 2.5e-66 223.6 0.1 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KPA39644.1 - 3.1e-05 23.6 0.3 0.044 13.5 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 KPA39644.1 - 0.0052 16.7 0.7 0.014 15.2 0.0 2.1 2 1 0 2 2 2 1 Right handed beta helix region LIAS_N PF16881.5 KPA39645.1 - 2.5e-18 66.4 0.0 5e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KPA39645.1 - 2.3e-14 54.1 0.0 4.6e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily CEND1 PF15677.5 KPA39646.1 - 0.025 15.1 3.6 0.033 14.7 3.6 1.2 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 ubiquitin PF00240.23 KPA39647.1 - 0.00055 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 KPA39647.1 - 0.029 15.1 0.0 0.048 14.3 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD GATase_5 PF13507.6 KPA39649.1 - 6e-98 327.1 0.0 8.5e-98 326.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KPA39649.1 - 2.5e-37 128.4 0.2 8e-25 87.8 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KPA39649.1 - 4.1e-23 81.6 0.0 7.7e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KPA39649.1 - 1.3e-19 70.5 0.0 3.7e-19 69.0 0.0 1.9 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain TonB_C PF03544.14 KPA39650.1 - 0.003 18.0 0.2 22 5.6 0.0 7.2 3 1 1 4 4 4 1 Gram-negative bacterial TonB protein C-terminal DUF5050 PF16472.5 KPA39650.1 - 0.096 11.9 0.1 1.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5050) DUF2270 PF10028.9 KPA39652.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) p450 PF00067.22 KPA39653.1 - 1.5e-28 99.8 0.0 1.8e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Isochorismatase PF00857.20 KPA39654.1 - 2.1e-23 83.4 0.0 1e-22 81.2 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family HMG-CoA_red PF00368.18 KPA39655.1 - 2.7e-141 470.9 4.0 3.8e-141 470.4 4.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KPA39655.1 - 6.6e-51 172.3 0.8 1.1e-50 171.6 0.8 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KPA39655.1 - 1.1e-16 61.1 8.7 1.4e-15 57.5 8.7 2.4 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KPA39655.1 - 3.1e-11 42.1 6.2 6.3e-11 41.1 6.1 1.5 1 1 0 1 1 1 1 Patched family MCRA PF06100.11 KPA39656.1 - 1.1e-30 106.9 0.0 1.4e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 KPA39656.1 - 2.4e-06 27.7 0.1 4.6e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AAL_decarboxy PF03306.13 KPA39656.1 - 0.043 13.2 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase MCRA PF06100.11 KPA39657.1 - 2.3e-104 350.0 0.0 2.5e-104 349.8 0.0 1.0 1 0 0 1 1 1 1 MCRA family HNH_2 PF13391.6 KPA39659.1 - 7.3e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease IBR PF01485.21 KPA39660.1 - 4.2e-10 39.7 39.3 1.6e-06 28.2 3.9 4.0 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KPA39660.1 - 1.4e-05 24.9 5.3 1.4e-05 24.9 5.3 3.6 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KPA39660.1 - 6.3e-05 22.7 4.1 6.3e-05 22.7 4.1 4.2 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KPA39660.1 - 0.0015 18.5 7.3 0.0015 18.5 7.3 4.7 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 KPA39660.1 - 0.0032 17.8 6.7 0.0032 17.8 6.7 4.1 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KPA39660.1 - 0.007 16.2 2.4 0.007 16.2 2.4 4.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA39660.1 - 0.013 15.3 3.5 0.013 15.3 3.5 4.6 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RSN1_7TM PF02714.15 KPA39661.1 - 4.5e-76 255.8 20.2 4.5e-76 255.8 20.2 2.2 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KPA39661.1 - 2e-41 141.3 3.3 7.9e-41 139.4 3.3 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KPA39661.1 - 6.2e-30 104.7 0.2 1.3e-29 103.6 0.2 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KPA39661.1 - 3e-24 85.0 0.1 1.2e-23 83.1 0.1 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter Neur_chan_memb PF02932.16 KPA39661.1 - 8.8 6.3 6.7 1.2e+02 2.6 5.4 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_M3 PF01432.20 KPA39662.1 - 5.4e-109 365.5 1.2 7.1e-109 365.1 1.2 1.1 1 0 0 1 1 1 1 Peptidase family M3 FTCD_C PF04961.12 KPA39662.1 - 1.5 8.5 5.3 0.44 10.3 1.7 1.8 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase WW PF00397.26 KPA39663.1 - 1.9e-10 40.6 2.1 3.7e-10 39.7 2.1 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 KPA39663.1 - 0.0011 19.1 21.9 0.0011 19.1 21.9 3.9 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) KinB_sensor PF16767.5 KPA39663.1 - 0.14 12.7 1.3 0.23 11.9 1.3 1.3 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB TPR_2 PF07719.17 KPA39663.1 - 0.59 10.4 7.7 2.9 8.2 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KPA39663.1 - 8.2 6.5 8.7 1.8 8.5 0.8 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C14 PF00656.22 KPA39664.1 - 2.7e-59 201.1 0.0 3.3e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain FTA2 PF13095.6 KPA39665.1 - 3.9e-49 167.2 0.0 5.1e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 rve PF00665.26 KPA39666.1 - 3.9e-10 40.0 0.0 8.3e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 KPA39666.1 - 1.3e-05 24.9 1.9 1.3e-05 24.9 1.9 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 KPA39666.1 - 4e-05 23.3 0.2 0.00011 21.9 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 KPA39666.1 - 0.023 14.5 0.0 0.062 13.1 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain zf-CCHC_2 PF13696.6 KPA39666.1 - 0.57 10.1 5.6 1.7 8.5 5.6 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KPA39666.1 - 0.6 10.3 5.4 1.4 9.1 5.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Use1 PF09753.9 KPA39667.1 - 0.0037 17.0 0.1 0.019 14.7 0.1 1.9 2 0 0 2 2 2 1 Membrane fusion protein Use1 Not3 PF04065.15 KPA39667.1 - 0.033 13.6 0.5 0.09 12.2 0.0 1.7 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component TACC_C PF05010.14 KPA39667.1 - 0.079 12.7 0.1 0.2 11.4 0.0 1.6 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA PF00004.29 KPA39668.1 - 8.6e-18 65.0 0.0 2e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPA39668.1 - 0.00057 19.7 0.0 0.0017 18.1 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPA39668.1 - 0.004 17.6 0.0 0.014 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 KPA39668.1 - 0.074 13.5 0.0 0.074 13.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KPA39668.1 - 0.11 12.8 0.6 0.38 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain RP-C_C PF11800.8 KPA39668.1 - 1.7 8.7 6.8 3.4 7.7 6.8 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region Mitofilin PF09731.9 KPA39668.1 - 2.2 7.0 16.2 3.4 6.4 16.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NPR3 PF03666.13 KPA39668.1 - 9.2 4.9 13.2 48 2.6 0.0 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 NmrA PF05368.13 KPA39670.1 - 8.4e-33 113.9 0.5 1.1e-32 113.5 0.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA39670.1 - 3.5e-13 49.8 0.1 1.1e-12 48.3 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KPA39670.1 - 1.4e-06 27.5 0.2 2e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KPA39670.1 - 1e-05 25.8 0.1 2.3e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPA39670.1 - 1.9e-05 24.2 0.1 0.00022 20.8 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPA39670.1 - 5.9e-05 23.0 0.1 0.00014 21.8 0.0 1.6 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.24 KPA39670.1 - 6e-05 23.5 0.0 0.00021 21.7 0.1 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 KPA39670.1 - 0.00016 21.2 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Polysacc_synt_2 PF02719.15 KPA39670.1 - 0.00018 20.8 0.2 0.00026 20.2 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KPA39670.1 - 0.0029 17.0 0.1 0.0069 15.8 0.1 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KPA39670.1 - 0.0036 16.8 0.4 0.011 15.1 0.2 1.8 2 0 0 2 2 2 1 short chain dehydrogenase DXP_reductoisom PF02670.16 KPA39670.1 - 0.0051 17.5 0.5 0.012 16.3 0.2 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 KPA39670.1 - 0.015 15.4 0.4 0.032 14.4 0.1 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 KPA39670.1 - 0.049 13.9 0.7 0.11 12.7 0.4 1.8 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_23 PF13489.6 KPA39672.1 - 1.5e-15 57.4 0.0 3e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA39672.1 - 3.7e-15 56.0 0.0 5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA39672.1 - 6.5e-13 49.3 0.0 1e-12 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA39672.1 - 1.5e-12 48.1 0.0 4e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA39672.1 - 7.8e-12 45.7 0.0 2.3e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA39672.1 - 0.0044 16.4 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KPA39672.1 - 0.024 13.6 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DREV PF05219.12 KPA39672.1 - 0.038 13.1 0.0 0.075 12.1 0.0 1.4 2 0 0 2 2 2 0 DREV methyltransferase TehB PF03848.14 KPA39672.1 - 0.06 12.7 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB MTS PF05175.14 KPA39672.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain PAN_4 PF14295.6 KPA39673.1 - 2.8e-06 27.1 9.9 0.00025 20.9 0.6 2.7 2 1 0 2 2 2 2 PAN domain PAN_1 PF00024.26 KPA39673.1 - 6.9e-05 22.7 2.0 6.9e-05 22.7 2.0 3.1 1 1 2 3 3 3 2 PAN domain PAN_3 PF08277.12 KPA39673.1 - 0.023 14.5 4.9 0.4 10.5 0.5 2.8 2 0 0 2 2 2 0 PAN-like domain FAD-SLDH PF12318.8 KPA39673.1 - 0.063 13.3 0.2 0.096 12.7 0.2 1.3 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase CarbpepA_inh PF02977.15 KPA39673.1 - 1.6 8.6 12.9 0.86 9.4 3.1 2.9 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor PAN_2 PF08276.11 KPA39673.1 - 4.6 7.4 13.3 0.063 13.4 1.9 2.8 3 0 0 3 3 3 0 PAN-like domain Corona_NS2A PF05213.12 KPA39674.1 - 0.043 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Coronavirus NS2A protein zf-CGNR PF11706.8 KPA39674.1 - 2.8 7.9 5.9 1.2 9.0 0.6 2.6 2 0 0 2 2 2 0 CGNR zinc finger Ank_2 PF12796.7 KPA39675.1 - 4.6e-20 72.0 2.9 5.6e-13 49.3 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA39675.1 - 3.4e-13 49.5 0.8 2.7e-08 33.9 0.2 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA39675.1 - 2.8e-10 39.5 0.1 0.00023 21.3 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KPA39675.1 - 5.8e-10 39.2 0.4 6.4e-06 26.4 0.2 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KPA39675.1 - 8.9e-09 35.7 0.1 0.0001 22.8 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 KPA39675.1 - 0.012 15.6 0.0 0.78 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Ketoacyl-synt_2 PF13723.6 KPA39675.1 - 0.022 14.4 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain ResIII PF04851.15 KPA39675.1 - 0.05 13.6 0.2 0.13 12.2 0.2 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Amidohydro_1 PF01979.20 KPA39675.1 - 0.11 11.7 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase family TP6A_N PF04406.14 KPA39676.1 - 1.5e-22 79.3 0.1 3.8e-22 78.0 0.1 1.7 2 0 0 2 2 2 1 Type IIB DNA topoisomerase SQHop_cyclase_C PF13243.6 KPA39677.1 - 9.7e-46 156.3 0.4 4.2e-43 147.7 0.3 2.6 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KPA39677.1 - 4.9e-41 140.7 5.5 1.1e-36 126.4 0.5 3.6 4 2 2 6 6 6 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KPA39677.1 - 1.2e-27 95.3 10.0 7.9e-09 35.1 0.2 5.5 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KPA39677.1 - 0.013 14.9 0.3 2.5 7.4 0.0 3.9 4 1 1 5 5 5 0 Pectic acid lyase NSP2-B_epitope PF14757.6 KPA39678.1 - 0.034 13.9 3.4 0.059 13.1 3.4 1.3 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein DUF2868 PF11067.8 KPA39678.1 - 0.059 12.9 1.0 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) DUF2192 PF09958.9 KPA39678.1 - 0.084 12.4 0.5 0.16 11.5 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) DUF826 PF05696.11 KPA39678.1 - 0.2 11.7 2.5 0.4 10.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF826) Pex14_N PF04695.13 KPA39678.1 - 1.6 9.4 7.5 0.26 11.9 2.9 2.2 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SGS PF05002.15 KPA39679.1 - 6.7e-29 99.8 3.0 6.7e-29 99.8 3.0 3.2 5 0 0 5 5 5 1 SGS domain TPR_2 PF07719.17 KPA39679.1 - 1.3e-09 37.5 6.5 0.00064 19.6 1.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat CS PF04969.16 KPA39679.1 - 3.3e-07 31.2 0.2 1e-06 29.7 0.2 1.8 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 KPA39679.1 - 2.6e-05 23.8 6.0 0.00059 19.5 0.9 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPA39679.1 - 0.00054 19.8 0.7 0.82 9.8 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KPA39679.1 - 0.0016 18.9 3.0 0.085 13.5 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA39679.1 - 0.025 14.7 0.2 0.099 12.9 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPA39679.1 - 0.051 14.2 15.1 0.12 13.1 1.4 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KPA39679.1 - 0.12 12.5 1.3 0.38 10.9 1.0 2.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KPA39679.1 - 0.23 11.7 6.6 5.8 7.3 0.4 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA39679.1 - 0.31 11.3 3.5 1.3 9.3 0.2 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KPA39679.1 - 0.84 10.6 8.1 6.4 7.9 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TauD PF02668.16 KPA39680.1 - 5.7e-39 134.5 0.0 8.1e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KPA39680.1 - 5.9e-08 33.2 0.0 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KPA39680.1 - 0.0095 15.1 0.0 0.03 13.4 0.0 1.7 2 0 0 2 2 2 1 CsiD tRNA_int_endo PF01974.17 KPA39681.1 - 1.9e-18 66.3 0.0 3.9e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KPA39681.1 - 5.5e-05 22.8 0.0 0.041 13.6 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Guanylate_kin PF00625.21 KPA39682.1 - 4.3e-61 205.8 0.0 6.5e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase Glyco_transf_21 PF13506.6 KPA39682.1 - 9.8e-15 54.4 0.2 2.2e-07 30.5 0.0 3.4 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KPA39682.1 - 2.4e-06 27.6 0.0 6.4e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 AAA_16 PF13191.6 KPA39682.1 - 0.00011 22.6 0.0 0.00022 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Glycos_transf_2 PF00535.26 KPA39682.1 - 0.00019 21.3 0.0 0.00067 19.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 RsgA_GTPase PF03193.16 KPA39682.1 - 0.00027 20.9 0.0 0.0006 19.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KPA39682.1 - 0.00045 20.3 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KPA39682.1 - 0.0032 18.0 0.0 0.0096 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KPA39682.1 - 0.025 14.9 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KPA39682.1 - 0.026 14.7 0.2 0.17 12.0 0.2 2.2 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KPA39682.1 - 0.03 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 KPA39682.1 - 0.065 13.7 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KPA39682.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Haem_degrading PF03928.14 KPA39684.1 - 9.2e-15 54.7 0.0 1.5e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Haem-degrading Peptidase_M35 PF02102.15 KPA39685.1 - 9.8e-59 199.0 2.1 1.1e-58 198.8 2.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KPA39685.1 - 1.9e-26 93.3 0.4 2.8e-26 92.8 0.4 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M7 PF02031.16 KPA39685.1 - 0.00025 21.2 0.6 0.11 12.7 0.1 2.4 2 0 0 2 2 2 2 Streptomyces extracellular neutral proteinase (M7) family TruB_C PF09142.11 KPA39685.1 - 0.5 10.2 3.2 7.3 6.5 2.1 2.6 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Ras PF00071.22 KPA39686.1 - 3.5e-49 166.5 0.0 4.2e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA39686.1 - 8.7e-30 103.4 0.1 2.1e-29 102.1 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA39686.1 - 1.2e-10 41.1 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KPA39686.1 - 0.00016 21.7 0.0 0.00031 20.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KPA39686.1 - 0.00052 20.4 0.1 0.003 17.9 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 KPA39686.1 - 0.0023 17.3 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KPA39686.1 - 0.013 14.6 2.3 0.66 9.1 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.12 KPA39686.1 - 0.015 14.8 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KPA39686.1 - 0.022 14.3 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KPA39686.1 - 0.026 14.4 0.1 7.9 6.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KPA39686.1 - 0.057 13.8 0.1 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KPA39686.1 - 0.059 13.1 0.1 0.097 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KPA39686.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 KPA39686.1 - 0.089 12.8 0.1 0.2 11.7 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KPA39686.1 - 0.11 12.7 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KPA39686.1 - 0.17 11.2 0.6 0.23 10.7 0.1 1.5 2 0 0 2 2 2 0 Septin ATPase PF06745.13 KPA39686.1 - 0.19 11.1 0.3 0.29 10.5 0.3 1.2 1 0 0 1 1 1 0 KaiC Homeodomain PF00046.29 KPA39687.1 - 1.1e-13 50.7 2.9 3.2e-13 49.3 2.0 2.2 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KPA39687.1 - 0.031 14.2 0.3 0.18 11.7 0.3 2.3 2 0 0 2 2 2 0 Homeobox KN domain NAD_kinase PF01513.21 KPA39688.1 - 1.9e-79 266.9 0.0 2.8e-79 266.4 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.21 KPA39689.1 - 3.9e-14 53.3 0.0 5.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KPA39689.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PTPA PF03095.15 KPA39690.1 - 8.8e-110 366.9 0.0 1e-109 366.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein TPP_enzyme_N PF02776.18 KPA39693.1 - 9.3e-55 184.9 0.0 2.1e-53 180.4 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KPA39693.1 - 1.9e-48 164.1 0.0 2.2e-47 160.6 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPA39693.1 - 2.4e-41 140.7 0.3 5.8e-41 139.4 0.2 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Dehydratase_SU PF02287.15 KPA39693.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Dehydratase small subunit Helicase_C PF00271.31 KPA39694.1 - 8.5e-11 42.2 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pyr_excise PF03013.14 KPA39696.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 1 1 2 2 2 0 Pyrimidine dimer DNA glycosylase Seryl_tRNA_N PF02403.22 KPA39697.1 - 0.096 12.9 0.5 0.17 12.1 0.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 KPA39697.1 - 0.45 10.5 2.1 2.9 8.0 0.6 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PAP1 PF08601.10 KPA39697.1 - 2.3 7.9 15.5 4.2 7.0 15.3 1.5 1 1 0 1 1 1 0 Transcription factor PAP1 p450 PF00067.22 KPA39698.1 - 6e-44 150.5 0.0 8e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KPA39699.1 - 1.3e-06 28.1 0.5 4.8e-06 26.4 0.5 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KPA39699.1 - 0.88 9.5 3.9 20 5.2 0.1 2.7 3 0 0 3 3 3 0 F-box domain F-box PF00646.33 KPA39702.1 - 0.74 9.8 3.5 1.8 8.6 3.5 1.6 1 0 0 1 1 1 0 F-box domain BAR PF03114.18 KPA39703.1 - 2.5e-70 236.8 8.8 3.1e-70 236.5 8.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KPA39703.1 - 1.6e-14 53.2 0.5 3e-14 52.3 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KPA39703.1 - 5e-12 45.5 0.1 9.1e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPA39703.1 - 1e-09 37.9 0.3 7.6e-09 35.1 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain TMPIT PF07851.13 KPA39703.1 - 0.29 10.3 4.7 0.54 9.5 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein Aminotran_5 PF00266.19 KPA39704.1 - 8.1e-92 308.0 0.0 1e-91 307.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KPA39704.1 - 3.5e-07 29.8 0.1 5.6e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KPA39704.1 - 6.7e-06 25.7 0.1 4.3e-05 23.0 0.0 2.1 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KPA39704.1 - 0.0037 15.8 0.0 0.0055 15.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 KPA39704.1 - 0.025 13.3 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DUF3942 PF13078.6 KPA39704.1 - 0.18 12.1 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) CsbD PF05532.12 KPA39705.1 - 1.6e-20 72.8 20.6 1.4e-12 47.3 2.6 3.8 2 1 1 3 3 3 3 CsbD-like MARVEL PF01284.23 KPA39707.1 - 1.1e-14 54.7 9.1 1.3e-14 54.5 9.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 KPA39707.1 - 0.011 15.5 3.3 0.18 11.6 3.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF588) DUF4231 PF14015.6 KPA39707.1 - 0.53 10.8 3.8 4.5 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF485 PF04341.12 KPA39707.1 - 1.9 8.5 6.2 0.8 9.7 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF485 APG5 PF04106.12 KPA39708.1 - 2.7e-45 154.7 0.0 9.3e-45 153.0 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 DUF2947 PF11163.8 KPA39708.1 - 0.12 12.2 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) WD40 PF00400.32 KPA39709.1 - 9e-21 73.8 13.5 2.2e-05 25.1 0.1 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA39709.1 - 1.9e-12 47.3 0.8 0.012 15.9 0.0 5.3 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KPA39709.1 - 0.078 11.7 0.0 0.9 8.2 0.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.8 KPA39709.1 - 0.16 10.6 0.5 11 4.6 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Zn_clus PF00172.18 KPA39711.1 - 9.2e-09 35.3 13.1 1.5e-08 34.6 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SnAC PF14619.6 KPA39711.1 - 0.44 11.2 2.7 1.3 9.7 0.9 2.4 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex Glyco_hydro_115 PF15979.5 KPA39713.1 - 1.8e-136 455.0 2.7 2.8e-136 454.4 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KPA39713.1 - 1.9e-46 158.0 0.0 3.5e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain NAC PF01849.18 KPA39713.1 - 0.21 11.6 0.1 0.54 10.3 0.1 1.7 1 0 0 1 1 1 0 NAC domain GST_N_2 PF13409.6 KPA39715.1 - 1.4e-07 31.7 0.0 3.3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPA39715.1 - 3.3e-05 24.2 0.0 9.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPA39715.1 - 0.0052 16.8 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA39715.1 - 0.0098 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PI-PLC-X PF00388.19 KPA39716.1 - 5.6e-65 217.4 0.0 8.3e-65 216.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KPA39716.1 - 2.1e-41 140.8 0.0 3.7e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KPA39716.1 - 0.0039 17.5 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain MFS_1 PF07690.16 KPA39717.1 - 2.3e-24 86.0 65.4 4.8e-18 65.2 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_14 PF08484.11 KPA39717.1 - 0.2 11.5 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Aminotran_3 PF00202.21 KPA39718.1 - 2.4e-93 313.0 0.0 2.8e-93 312.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III MFS_1 PF07690.16 KPA39719.1 - 3.5e-38 131.4 27.1 4.9e-38 131.0 27.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ATPase_gene1 PF09527.10 KPA39719.1 - 0.0061 16.7 0.8 0.0061 16.7 0.8 3.5 4 0 0 4 4 4 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Alpha-amylase PF00128.24 KPA39720.1 - 5.1e-105 351.7 0.1 7.8e-105 351.1 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 KPA39720.1 - 0.0057 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.6 KPA39720.1 - 0.0064 15.6 0.1 0.026 13.6 0.0 2.0 3 0 0 3 3 3 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 KPA39720.1 - 0.16 12.1 0.0 1.3 9.2 0.0 2.3 1 1 1 2 2 2 0 Maltogenic Amylase, C-terminal domain 5-FTHF_cyc-lig PF01812.20 KPA39720.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family Sugar_tr PF00083.24 KPA39721.1 - 7.5e-70 236.0 17.9 6e-45 153.9 2.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPA39721.1 - 9.5e-13 47.8 35.2 2e-10 40.2 26.6 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA39721.1 - 5.3 5.8 14.4 0.12 11.2 3.6 2.4 2 1 0 2 2 2 0 MFS_1 like family Fungal_trans PF04082.18 KPA39722.1 - 1.7e-06 27.3 3.0 1.7e-06 27.3 3.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Shikimate_dh_N PF08501.11 KPA39723.1 - 5.9e-21 74.5 0.0 1.1e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KPA39723.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 KPA39723.1 - 0.32 10.8 2.3 0.32 10.8 0.6 1.9 2 0 0 2 2 2 0 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_dh_N PF08501.11 KPA39724.1 - 1.2e-45 153.6 0.1 5.6e-22 77.8 0.0 2.7 2 0 0 2 2 2 2 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 KPA39724.1 - 5.7e-25 88.9 0.0 9.6e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_DH PF01488.20 KPA39724.1 - 3.8e-16 59.4 0.7 5.8e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase SKI PF01202.22 KPA39724.1 - 2.2e-14 53.9 0.0 5.4e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 KPA39724.1 - 3.2e-11 42.8 0.5 6e-11 41.9 0.5 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 KPA39724.1 - 1.4e-05 25.6 1.3 0.074 13.6 0.2 2.7 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 KPA39724.1 - 0.0041 16.5 0.5 0.78 9.1 0.0 3.1 3 0 0 3 3 3 1 ThiF family XdhC_C PF13478.6 KPA39724.1 - 0.015 15.8 0.0 4.5 7.8 0.0 2.8 2 0 0 2 2 2 0 XdhC Rossmann domain OCD_Mu_crystall PF02423.15 KPA39724.1 - 0.029 13.3 0.4 2 7.3 0.1 2.2 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family adh_short PF00106.25 KPA39724.1 - 0.094 12.2 1.2 2.9 7.3 0.1 2.5 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_7 PF13241.6 KPA39724.1 - 0.11 12.9 0.0 2.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Fungal_trans PF04082.18 KPA39725.1 - 1.2e-12 47.5 0.3 1.8e-12 46.9 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA39725.1 - 7.9e-06 25.9 13.6 7.9e-06 25.9 13.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AP_endonuc_2 PF01261.24 KPA39726.1 - 2.9e-26 92.2 0.0 3.7e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel T4SS_TraI PF16932.5 KPA39727.1 - 0.088 12.0 0.0 0.18 10.9 0.0 1.5 2 0 0 2 2 2 0 Type IV secretory system, conjugal DNA-protein transfer Shikimate_dh_N PF08501.11 KPA39728.1 - 4.5e-17 62.1 0.0 9.7e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KPA39728.1 - 0.0033 17.5 0.0 0.0064 16.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase zf-C2H2_2 PF12756.7 KPA39729.1 - 4.3e-25 88.0 5.4 1.3e-22 80.0 1.9 2.8 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KPA39729.1 - 0.00025 21.6 7.1 2.6 9.1 0.0 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger OTT_1508_deam PF14441.6 KPA39729.1 - 0.11 12.6 0.1 0.41 10.7 0.1 2.0 1 0 0 1 1 1 0 OTT_1508-like deaminase zf-met PF12874.7 KPA39729.1 - 0.51 10.8 2.9 0.62 10.5 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ABC2_membrane PF01061.24 KPA39730.1 - 2.4e-82 275.4 65.1 4.8e-44 150.3 16.8 3.6 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KPA39730.1 - 5.4e-37 127.4 0.1 3.3e-18 66.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KPA39730.1 - 4.6e-36 122.6 4.1 1.2e-30 105.2 0.1 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KPA39730.1 - 1.3e-17 64.2 0.0 4.8e-17 62.3 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KPA39730.1 - 7.7e-07 28.9 0.2 0.00015 21.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KPA39730.1 - 1.7e-06 27.4 11.1 1.7e-06 27.4 11.1 3.5 2 1 0 3 3 3 1 ABC-2 family transporter protein AAA_16 PF13191.6 KPA39730.1 - 2.2e-06 28.2 0.6 0.00085 19.7 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KPA39730.1 - 1.6e-05 24.9 0.4 0.0049 16.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KPA39730.1 - 0.00013 22.5 0.1 0.0064 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPA39730.1 - 0.00014 22.0 1.8 0.0044 17.2 0.1 2.8 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KPA39730.1 - 0.00019 21.1 1.1 0.045 13.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KPA39730.1 - 0.0012 18.8 0.2 1.3 8.8 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KPA39730.1 - 0.0027 17.3 1.6 0.038 13.6 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 KPA39730.1 - 0.0033 16.9 0.0 0.39 10.1 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KPA39730.1 - 0.0085 16.2 0.2 2.8 8.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase dNK PF01712.19 KPA39730.1 - 0.011 15.6 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_22 PF13401.6 KPA39730.1 - 0.012 15.9 1.1 2 8.7 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KPA39730.1 - 0.022 14.4 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KPA39730.1 - 0.036 14.5 0.1 8.8 6.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KPA39730.1 - 0.072 13.0 2.2 2 8.3 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 KPA39730.1 - 0.13 12.7 0.4 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain SGL PF08450.12 KPA39733.1 - 6.9e-10 38.9 0.1 1.6e-09 37.7 0.1 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Oxidored_FMN PF00724.20 KPA39735.1 - 1.9e-65 221.4 0.0 2.3e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KPA39735.1 - 1.8e-05 24.0 0.1 0.00023 20.4 0.1 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KPA39735.1 - 0.0095 15.4 0.1 0.017 14.6 0.1 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein E3_binding PF02817.17 KPA39735.1 - 0.031 14.6 0.1 17 5.8 0.0 3.9 5 0 0 5 5 5 0 e3 binding domain IMPDH PF00478.25 KPA39735.1 - 0.094 11.7 1.0 2.6 7.0 0.3 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Amidase PF01425.21 KPA39736.1 - 9.2e-87 291.9 0.0 1.8e-86 290.9 0.0 1.4 1 1 0 1 1 1 1 Amidase p450 PF00067.22 KPA39737.1 - 1.9e-80 270.9 0.0 2.5e-80 270.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KPA39738.1 - 0.00016 21.7 9.7 0.00037 20.6 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy PF03171.20 KPA39739.1 - 9.5e-17 61.3 0.0 1.8e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KPA39739.1 - 2e-05 25.3 0.1 3.6e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Acetyltransf_1 PF00583.25 KPA39740.1 - 0.00082 19.6 0.0 0.00094 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA39740.1 - 0.00092 19.6 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4113 PF13438.6 KPA39740.1 - 0.0048 16.9 0.2 0.021 14.9 0.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4113) Acetyltransf_10 PF13673.7 KPA39740.1 - 0.024 14.6 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pyridoxal_deC PF00282.19 KPA39741.1 - 3.3e-59 200.5 0.0 2.9e-52 177.6 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KPA39741.1 - 5.8e-09 35.4 0.0 8.9e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KPA39741.1 - 1.2e-06 28.1 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KPA39741.1 - 0.0037 16.5 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KPA39741.1 - 0.026 13.9 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.16 KPA39742.1 - 5.5e-13 48.6 48.1 3e-10 39.6 12.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily 7TM_GPCR_Srh PF10318.9 KPA39742.1 - 0.00011 21.3 2.7 0.00011 21.3 2.7 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srh GPHR_N PF12537.8 KPA39743.1 - 0.17 12.0 0.2 0.25 11.5 0.2 1.3 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal HET PF06985.11 KPA39744.1 - 6.2e-12 46.1 0.8 3.7e-11 43.6 0.8 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Astacin PF01400.24 KPA39745.1 - 2.5e-06 27.3 0.8 8.3e-06 25.5 0.4 2.0 1 1 1 2 2 2 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KPA39745.1 - 0.00036 20.4 1.7 0.013 15.3 1.7 2.2 1 1 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.13 KPA39745.1 - 0.0022 17.9 0.3 0.021 14.7 0.0 2.3 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A DUF3810 PF12725.7 KPA39745.1 - 0.0022 17.4 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) Reprolysin_4 PF13583.6 KPA39745.1 - 0.008 15.8 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KPA39745.1 - 0.052 14.1 0.1 0.77 10.3 0.0 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Glyco_hydro_18 PF00704.28 KPA39746.1 - 2.2e-53 182.1 0.2 3.5e-53 181.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_S8 PF00082.22 KPA39746.1 - 8.1e-13 48.3 0.0 1.7e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Subtilase family Chitin_bind_1 PF00187.19 KPA39746.1 - 2.6e-09 37.4 25.1 1.5e-06 28.6 7.8 3.1 2 0 0 2 2 2 2 Chitin recognition protein p450 PF00067.22 KPA39747.1 - 6.4e-89 298.8 0.0 7.7e-89 298.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KPA39748.1 - 4.6e-22 78.4 25.2 6.2e-22 78.0 23.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KPA39751.1 - 1.4e-21 76.7 0.3 3.8e-21 75.3 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KPA39752.1 - 1.5e-39 135.9 39.3 6.4e-33 114.1 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA39752.1 - 8.3e-15 54.6 0.1 8.3e-15 54.6 0.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter GMC_oxred_N PF00732.19 KPA39754.1 - 3.2e-42 144.9 0.2 4.9e-42 144.3 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA39754.1 - 1.1e-29 103.9 0.0 2.8e-29 102.5 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPA39754.1 - 6.2e-07 28.8 0.2 5.2e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA39754.1 - 1.4e-06 27.8 0.3 1.8e-05 24.1 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA39754.1 - 0.00039 19.8 0.1 0.00064 19.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPA39754.1 - 0.0014 18.9 0.2 0.0051 17.0 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA39754.1 - 0.0019 17.9 0.5 0.34 10.5 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPA39754.1 - 0.0053 16.0 0.1 0.014 14.6 0.1 1.7 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KPA39754.1 - 0.017 13.8 0.1 0.03 13.0 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 KPA39754.1 - 0.061 12.9 0.5 0.098 12.2 0.5 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 KPA39754.1 - 0.074 12.4 0.6 0.12 11.7 0.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KPA39754.1 - 0.28 10.2 0.9 0.71 8.9 0.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA_C PF08546.11 KPA39755.1 - 6.7e-16 58.6 0.0 2.2e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KPA39755.1 - 1.5e-14 53.9 0.0 2.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KPA39755.1 - 0.0002 20.8 1.5 0.00044 19.7 0.5 1.8 2 0 0 2 2 2 1 ThiF family NAD_binding_7 PF13241.6 KPA39755.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.12 KPA39755.1 - 0.16 11.6 0.0 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Arf PF00025.21 KPA39756.1 - 1.2e-74 249.6 0.0 1.3e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KPA39756.1 - 5.2e-15 55.7 0.0 6.9e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KPA39756.1 - 7e-13 48.4 0.0 8.6e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KPA39756.1 - 4.6e-12 45.8 0.4 4.2e-08 32.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KPA39756.1 - 1.2e-11 44.5 0.0 1.4e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KPA39756.1 - 1.3e-08 34.5 0.0 1.7e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KPA39756.1 - 5.2e-07 29.8 0.0 8.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPA39756.1 - 0.00013 21.6 0.0 0.011 15.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KPA39756.1 - 0.0057 16.2 0.9 0.022 14.3 0.9 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 KPA39756.1 - 0.12 13.0 0.1 0.2 12.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain Skp1 PF01466.19 KPA39757.1 - 1.7e-29 101.7 0.4 3.4e-29 100.7 0.4 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KPA39757.1 - 3.4e-23 81.6 0.4 7.8e-23 80.4 0.2 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Trnau1ap PF17654.1 KPA39757.1 - 0.065 14.1 1.0 0.11 13.3 1.0 1.4 1 1 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins Glyco_transf_22 PF03901.17 KPA39758.1 - 2.6e-59 201.5 16.8 3.3e-59 201.2 16.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ribosomal_L1 PF00687.21 KPA39759.1 - 2.4e-45 154.8 0.1 2.8e-45 154.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF2428 PF10350.9 KPA39760.1 - 2.9e-65 220.3 1.2 7.3e-65 219.0 0.7 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KPA39760.1 - 3.7e-05 23.6 2.9 0.46 10.9 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat DUF2781 PF10914.8 KPA39760.1 - 0.1 13.0 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) DUF3074 PF11274.8 KPA39761.1 - 7.3e-60 202.1 0.5 1.4e-57 194.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.19 KPA39761.1 - 0.0032 16.9 0.0 0.022 14.2 0.0 2.2 2 0 0 2 2 2 1 START domain Caldesmon PF02029.15 KPA39761.1 - 3.6 6.2 40.9 9.2 4.9 40.9 1.6 1 1 0 1 1 1 0 Caldesmon GREB1 PF15782.5 KPA39761.1 - 6.3 3.8 10.6 8.9 3.3 10.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MCU PF04678.13 KPA39761.1 - 6.6 6.8 21.0 0.89 9.6 1.4 2.8 2 1 1 3 3 3 0 Mitochondrial calcium uniporter VASt PF16016.5 KPA39762.1 - 8.3e-35 120.5 5.4 8.4e-34 117.2 1.5 2.6 3 0 0 3 3 3 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KPA39762.1 - 3.6e-17 62.9 0.0 6.6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KPA39762.1 - 1.3e-05 25.6 0.0 4.6e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 PH domain BAR PF03114.18 KPA39762.1 - 0.0045 16.7 0.1 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 BAR domain GRAM PF02893.20 KPA39762.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 GRAM domain eRF1_2 PF03464.15 KPA39763.1 - 5.1e-46 156.3 0.0 9e-46 155.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KPA39763.1 - 1.3e-39 135.2 0.6 2.7e-39 134.1 0.6 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KPA39763.1 - 1.6e-21 76.6 0.0 2.7e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KPA39763.1 - 1.9e-10 41.2 0.2 5.5e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KPA39763.1 - 1.2e-09 38.5 0.0 2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Ank_2 PF12796.7 KPA39765.1 - 1.4e-05 25.6 1.2 0.002 18.6 0.5 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA39765.1 - 0.00021 21.5 0.1 0.00067 19.9 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPA39765.1 - 0.077 13.6 3.2 0.26 11.9 0.1 2.9 1 1 2 3 3 3 0 Ankyrin repeats (many copies) DUF2884 PF11101.8 KPA39766.1 - 0.08 12.4 2.1 0.11 12.0 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Ank_5 PF13857.6 KPA39767.1 - 8.5e-07 29.1 0.1 0.0029 17.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA39767.1 - 5.2e-06 26.4 0.2 0.84 10.4 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KPA39767.1 - 1.7e-05 25.3 0.0 0.0074 16.9 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KPA39767.1 - 6.2e-05 23.3 0.0 3.5 8.2 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KPA39767.1 - 0.00047 20.7 0.1 2.8 8.6 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) DUF5049 PF16468.5 KPA39767.1 - 0.13 12.1 0.2 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5049) PARP PF00644.20 KPA39768.1 - 1.9e-46 158.1 0.0 3.7e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KPA39768.1 - 8.7e-40 136.0 0.1 2.2e-39 134.7 0.1 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KPA39768.1 - 2.8e-22 78.6 0.2 7.7e-22 77.2 0.2 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 KPA39768.1 - 3.2e-08 33.8 0.0 8e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KPA39768.1 - 5.4e-06 26.3 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KPA39768.1 - 0.0043 17.4 0.0 0.0093 16.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Glyco_hydro_64 PF16483.5 KPA39770.1 - 6.7e-125 417.2 0.1 7.7e-125 417.0 0.1 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Acyl-CoA_dh_M PF02770.19 KPA39771.1 - 6.1e-05 23.2 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HTH_Tnp_Tc5 PF03221.16 KPA39772.1 - 0.056 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain MYO10_CC PF16735.5 KPA39772.1 - 0.14 12.2 4.0 0.12 12.5 1.6 2.2 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain FapA PF03961.13 KPA39772.1 - 4.2 5.9 8.0 5.5 5.5 8.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlxA PF14282.6 KPA39772.1 - 7.2 6.7 9.9 20 5.3 9.9 1.8 1 1 0 1 1 1 0 FlxA-like protein NAD_binding_8 PF13450.6 KPA39773.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPA39773.1 - 0.0023 18.0 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPA39773.1 - 0.047 12.9 0.0 0.052 12.8 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA39773.1 - 0.055 12.7 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Glu_dehyd_C PF16912.5 KPA39773.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FMO-like PF00743.19 KPA39773.1 - 0.12 10.7 0.0 0.3 9.4 0.0 1.5 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like HI0933_like PF03486.14 KPA39773.1 - 0.25 10.0 0.2 0.38 9.4 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Ring_hydroxyl_A PF00848.19 KPA39774.1 - 9.4e-21 74.8 8.4 3.1e-10 40.4 3.6 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) PRTase_3 PF15610.6 KPA39774.1 - 0.029 13.6 0.1 0.061 12.5 0.1 1.5 1 0 0 1 1 1 0 PRTase ComF-like DAO PF01266.24 KPA39775.1 - 1.1e-32 114.0 0.0 1.6e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPA39775.1 - 4.2e-07 30.1 0.1 0.006 16.6 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 KPA39775.1 - 6.4e-06 25.5 0.4 2.2e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KPA39775.1 - 5.3e-05 22.6 0.0 0.11 11.7 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA39775.1 - 0.00042 20.5 0.0 0.0016 18.6 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPA39775.1 - 0.0035 16.7 0.2 2.3 7.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KPA39775.1 - 0.0076 16.5 0.1 0.18 12.1 0.0 2.5 2 1 0 2 2 2 1 TrkA-N domain GMC_oxred_N PF00732.19 KPA39775.1 - 0.017 14.5 0.0 5.5 6.3 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Thi4 PF01946.17 KPA39775.1 - 0.027 13.7 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KPA39775.1 - 0.061 12.4 0.0 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KPA39775.1 - 0.088 11.5 0.0 1.2 7.8 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KPA39775.1 - 0.11 11.5 0.1 2 7.4 0.1 2.1 1 1 0 1 1 1 0 FAD binding domain adh_short_C2 PF13561.6 KPA39776.1 - 1e-37 130.0 0.0 1.5e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA39776.1 - 1.2e-19 70.5 0.1 1.9e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Zn_clus PF00172.18 KPA39776.1 - 1.6e-08 34.5 10.8 3.5e-08 33.4 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA39776.1 - 1.5e-06 27.4 0.9 2.5e-06 26.7 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mem_trans PF03547.18 KPA39777.1 - 2.4e-13 49.3 16.3 8.2e-07 27.7 4.5 2.2 2 1 0 2 2 2 2 Membrane transport protein DUF3169 PF11368.8 KPA39777.1 - 0.51 9.8 0.0 0.51 9.8 0.0 3.5 4 1 1 5 5 5 0 Protein of unknown function (DUF3169) PhoLip_ATPase_C PF16212.5 KPA39777.1 - 1.3 8.7 12.7 1.5 8.5 0.5 2.2 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal Fungal_lectin PF07938.12 KPA39778.1 - 7.7e-07 28.8 0.2 0.019 14.4 0.1 2.4 2 0 0 2 2 2 2 Fungal fucose-specific lectin SKG6 PF08693.10 KPA39778.1 - 6e-06 25.6 0.8 1.4e-05 24.4 0.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CoatB PF10389.9 KPA39778.1 - 0.023 14.5 1.2 0.063 13.1 1.2 1.7 1 0 0 1 1 1 0 Bacteriophage coat protein B DUF4524 PF15025.6 KPA39778.1 - 0.14 11.9 0.1 4 7.2 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4524) OPT PF03169.15 KPA39779.1 - 1.4e-122 410.5 39.4 1.6e-122 410.3 39.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Amidase PF01425.21 KPA39780.1 - 3e-63 214.3 0.0 2.5e-62 211.3 0.0 2.0 1 1 0 1 1 1 1 Amidase adh_short_C2 PF13561.6 KPA39780.1 - 4.2e-51 173.7 0.0 8.7e-51 172.7 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA39780.1 - 6.9e-44 149.6 0.1 2.2e-43 148.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPA39780.1 - 0.00018 21.5 0.1 0.00047 20.1 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KPA39780.1 - 0.00035 20.1 0.0 0.0008 18.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GRDA PF04723.14 KPA39780.1 - 0.0078 16.0 0.7 0.11 12.3 0.0 2.6 3 0 0 3 3 3 1 Glycine reductase complex selenoprotein A DUF1776 PF08643.10 KPA39780.1 - 0.052 12.9 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sugar_tr PF00083.24 KPA39781.1 - 9.9e-81 271.9 16.8 1.2e-80 271.6 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA39781.1 - 1.8e-30 106.1 27.9 3.4e-27 95.3 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PA_decarbox PF05870.11 KPA39782.1 - 4.6e-11 42.6 0.4 5.4e-11 42.4 0.4 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) FGE-sulfatase PF03781.16 KPA39783.1 - 5.3e-18 65.5 0.7 7.8e-18 65.0 0.7 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KPA39783.1 - 1.3e-06 28.9 2.5 5e-06 27.1 0.3 2.5 2 0 0 2 2 2 1 DinB superfamily DUF4267 PF14087.6 KPA39784.1 - 3.4e-10 40.0 0.0 4e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Zn_clus PF00172.18 KPA39785.1 - 1e-09 38.3 9.4 2e-09 37.4 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA39785.1 - 1.2e-05 24.3 0.2 3.1e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sel1 PF08238.12 KPA39785.1 - 0.052 14.2 0.6 4.7 8.0 0.0 3.3 3 0 0 3 3 3 0 Sel1 repeat PhoR PF11808.8 KPA39785.1 - 0.13 12.6 0.1 1.3 9.5 0.0 2.5 2 1 1 3 3 3 0 Phosphate regulon sensor protein PhoR Asp PF00026.23 KPA39786.1 - 1.7e-64 218.2 5.4 2.7e-63 214.3 5.4 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA39786.1 - 4.8e-13 49.7 1.5 1.3e-09 38.6 0.9 3.2 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPA39786.1 - 7.9e-06 26.4 0.6 0.043 14.5 0.3 3.2 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KPA39786.1 - 0.00026 20.8 0.0 0.00075 19.3 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KPA39786.1 - 0.019 15.5 0.2 8.4 7.0 0.1 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease LRR_RI_capping PF18779.1 KPA39786.1 - 0.28 10.9 1.0 0.51 10.0 1.0 1.4 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat Fe-ADH PF00465.19 KPA39787.1 - 1e-63 215.4 0.0 1.4e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KPA39787.1 - 8.7e-09 35.4 0.0 0.0031 17.3 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Thioredoxin_13 PF18401.1 KPA39787.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain adh_short PF00106.25 KPA39788.1 - 3.5e-05 23.3 0.0 4.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA39788.1 - 0.22 11.0 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase p450 PF00067.22 KPA39789.1 - 3.9e-36 124.8 0.0 3.4e-26 92.0 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 DUF713 PF05218.14 KPA39790.1 - 0.058 13.1 0.9 0.65 9.7 0.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF713) gag_pre-integrs PF13976.6 KPA39791.1 - 0.00034 20.4 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Collectrin PF16959.5 KPA39792.1 - 0.026 14.3 0.2 0.036 13.8 0.2 1.3 1 0 0 1 1 1 0 Renal amino acid transporter Adeno_E3_CR2 PF02439.15 KPA39792.1 - 0.11 12.3 0.3 0.11 12.3 0.3 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KPA39792.1 - 0.12 13.3 0.0 0.42 11.5 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 KPA39792.1 - 0.17 11.8 0.4 0.22 11.4 0.4 1.1 1 0 0 1 1 1 0 Rifin VPDSG-CTERM PF18205.1 KPA39792.1 - 0.2 11.5 2.0 0.33 10.8 2.0 1.4 1 0 0 1 1 1 0 VPDSG-CTERM motif TMEM154 PF15102.6 KPA39792.1 - 0.74 9.7 3.6 1.9 8.4 3.6 1.6 1 1 0 1 1 1 0 TMEM154 protein family Condensation PF00668.20 KPA39793.1 - 0 1248.9 0.0 8.9e-50 169.7 0.0 11.1 10 3 0 10 10 10 9 Condensation domain AMP-binding PF00501.28 KPA39793.1 - 0 1189.6 9.5 9.4e-79 265.0 0.0 7.1 5 2 0 5 5 5 5 AMP-binding enzyme PP-binding PF00550.25 KPA39793.1 - 3.1e-67 222.8 1.2 3.6e-11 43.2 0.0 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site Transferase PF02458.15 KPA39793.1 - 5.3e-11 41.8 0.2 0.0051 15.5 0.0 5.4 6 0 0 6 6 6 4 Transferase family AMP-binding_C PF13193.6 KPA39793.1 - 4.6e-06 27.5 0.0 16 6.5 0.0 5.3 5 0 0 5 5 5 2 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 KPA39794.1 - 3.5e-45 153.9 0.0 7.9e-28 97.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KPA39794.1 - 2.2e-35 122.6 29.6 7.4e-28 98.0 13.5 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KPA39794.1 - 3.4e-12 46.3 3.5 0.00072 19.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPA39794.1 - 3.6e-07 30.3 0.0 0.0031 17.4 0.0 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPA39794.1 - 1.8e-06 27.6 1.1 0.0052 16.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KPA39794.1 - 4.6e-06 25.9 0.0 0.03 13.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 KPA39794.1 - 4.9e-05 23.6 0.4 0.12 12.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain ATP_bind_1 PF03029.17 KPA39794.1 - 7.7e-05 22.6 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KPA39794.1 - 0.0001 22.4 0.0 0.58 10.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA39794.1 - 0.00016 21.6 0.2 0.14 12.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KPA39794.1 - 0.00018 21.1 0.1 0.76 9.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KPA39794.1 - 0.00023 20.6 0.2 0.25 10.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_33 PF13671.6 KPA39794.1 - 0.00034 20.8 0.0 0.014 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KPA39794.1 - 0.00042 20.9 0.5 0.11 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA39794.1 - 0.0005 20.5 0.0 0.65 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KPA39794.1 - 0.00051 19.7 0.0 0.026 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KPA39794.1 - 0.00083 19.5 2.2 0.034 14.2 0.1 2.4 2 0 0 2 2 2 1 Dynamin family AAA PF00004.29 KPA39794.1 - 0.00095 19.6 0.1 1.6 9.2 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KPA39794.1 - 0.0011 18.7 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF87 PF01935.17 KPA39794.1 - 0.0015 18.7 1.5 0.056 13.5 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain Septin PF00735.18 KPA39794.1 - 0.0028 17.0 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 2 Septin AAA_30 PF13604.6 KPA39794.1 - 0.0064 16.2 0.2 0.75 9.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPA39794.1 - 0.0064 17.0 0.0 3.7 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KPA39794.1 - 0.0088 15.8 0.3 3.4 7.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain TrwB_AAD_bind PF10412.9 KPA39794.1 - 0.013 14.4 0.5 1.1 8.1 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 KPA39794.1 - 0.021 15.2 0.0 14 6.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 KPA39794.1 - 0.024 13.8 0.0 3.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 KPA39794.1 - 0.031 13.9 0.5 0.64 9.6 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KPA39794.1 - 0.036 13.8 0.5 0.97 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 KPA39794.1 - 0.038 14.0 0.0 0.92 9.5 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KPA39794.1 - 0.044 13.5 0.4 31 4.3 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein MeaB PF03308.16 KPA39794.1 - 0.046 12.7 0.2 0.23 10.4 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_ATPase PF09818.9 KPA39794.1 - 0.064 12.1 1.4 6.7 5.4 0.1 3.1 3 1 0 3 3 3 0 Predicted ATPase of the ABC class AAA_10 PF12846.7 KPA39794.1 - 0.13 11.2 0.2 6.1 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Pox_A32 PF04665.12 KPA39794.1 - 0.23 10.9 0.8 13 5.2 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Cu_amine_oxid PF01179.20 KPA39795.1 - 2.1e-122 409.0 6.0 2.6e-122 408.7 6.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KPA39795.1 - 5.4e-29 99.8 1.7 8e-29 99.2 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KPA39795.1 - 8.6e-07 29.1 0.0 2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain WD40 PF00400.32 KPA39796.1 - 3.4e-21 75.2 23.4 1.7e-07 31.8 1.8 6.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA39796.1 - 9.9e-11 41.8 1.3 0.57 10.5 0.0 5.2 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KPA39796.1 - 6.5e-08 32.2 1.8 0.00047 19.6 0.1 3.4 1 1 3 4 4 4 3 WD40-like domain Nup160 PF11715.8 KPA39796.1 - 1.5e-05 23.8 0.5 0.16 10.6 0.1 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KPA39796.1 - 5.7e-05 23.5 8.2 4.2 8.0 0.0 6.3 5 1 2 7 7 7 1 PQQ-like domain PQQ_2 PF13360.6 KPA39796.1 - 0.00048 19.8 1.5 0.0094 15.6 1.3 2.4 1 1 0 1 1 1 1 PQQ-like domain DUF5046 PF16465.5 KPA39796.1 - 0.018 14.5 0.1 0.084 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) Ge1_WD40 PF16529.5 KPA39796.1 - 0.082 11.9 0.1 18 4.2 0.0 2.9 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KPA39796.1 - 0.13 11.2 3.9 0.33 9.8 0.2 2.9 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ PF01011.21 KPA39796.1 - 0.15 12.0 0.3 78 3.5 0.0 4.5 6 0 0 6 6 6 0 PQQ enzyme repeat MFS_1 PF07690.16 KPA39797.1 - 3.1e-14 52.7 10.1 3.9e-14 52.4 10.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPA39797.1 - 4.9e-07 29.4 1.8 6.3e-07 29.0 1.8 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Nucleopor_Nup85 PF07575.13 KPA39799.1 - 2e-14 53.1 0.0 5.4e-10 38.5 0.0 2.6 2 1 0 2 2 2 2 Nup85 Nucleoporin Aconitase PF00330.20 KPA39800.1 - 7.1e-148 493.4 0.0 9e-148 493.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KPA39800.1 - 2e-37 128.4 0.0 3.4e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KPA39800.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Pkinase PF00069.25 KPA39802.1 - 1.1e-11 44.6 0.0 1.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KPA39802.1 - 4.8e-08 32.6 0.1 0.13 12.6 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KPA39802.1 - 6.4e-06 26.3 0.0 1.8e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KPA39802.1 - 0.0002 21.7 0.2 0.019 15.4 0.1 3.0 2 1 2 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.17 KPA39802.1 - 0.00078 18.8 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 KPA39802.1 - 0.0011 19.4 0.0 2.4 8.7 0.0 3.1 2 0 0 2 2 2 2 HEAT-like repeat Kinase-like PF14531.6 KPA39802.1 - 0.036 13.4 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF2462 PF09495.10 KPA39803.1 - 1.9e-11 44.5 8.0 1.9e-11 44.5 8.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Phospholamban PF04272.14 KPA39803.1 - 0.26 10.8 0.0 0.55 9.7 0.0 1.7 2 0 0 2 2 2 0 Phospholamban Helicase_C PF00271.31 KPA39804.1 - 0.018 15.4 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain AAA_12 PF13087.6 KPA39806.1 - 0.00027 20.6 0.0 0.00034 20.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KPA39806.1 - 0.0051 16.6 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain zf-CCHC_2 PF13696.6 KPA39807.1 - 2.4 8.1 3.8 1.4 8.8 0.5 2.2 2 0 0 2 2 2 0 Zinc knuckle Iso_dh PF00180.20 KPA39808.1 - 3.3e-74 250.1 0.0 4e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ino80_Iec3 PF14612.6 KPA39809.1 - 2.1e-51 175.9 4.7 1.5e-28 101.1 1.4 2.4 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling TMF_DNA_bd PF12329.8 KPA39809.1 - 0.15 12.1 0.2 0.15 12.1 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Sec1 PF00995.23 KPA39810.1 - 1.1e-128 431.1 0.0 1.2e-128 430.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-CCCH_4 PF18044.1 KPA39811.1 - 1.3e-08 34.4 2.8 2.1e-08 33.8 2.8 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KPA39811.1 - 3.4e-06 26.9 5.8 6e-06 26.1 5.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KPA39811.1 - 5.2e-05 23.0 2.7 9.5e-05 22.2 2.7 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KPA39811.1 - 0.0059 16.8 0.2 0.015 15.5 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KPA39811.1 - 0.023 15.2 2.4 0.041 14.4 2.4 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KPA39811.1 - 0.051 14.3 1.6 0.15 12.7 0.1 2.7 2 0 0 2 2 2 0 Torus domain Translin PF01997.16 KPA39812.1 - 1.1e-48 165.9 0.0 1.3e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 Translin family APC_N_CC PF16689.5 KPA39812.1 - 0.03 14.4 0.2 0.21 11.7 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF2250 PF10007.9 KPA39812.1 - 0.077 13.1 0.6 8.5 6.6 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) HET PF06985.11 KPA39813.1 - 6.8e-12 46.0 7.5 3.3e-10 40.5 1.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF411 PF04214.13 KPA39813.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF Sugar_tr PF00083.24 KPA39814.1 - 5.1e-83 279.4 22.5 5.8e-83 279.2 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA39814.1 - 8.3e-20 71.0 23.5 8.3e-20 71.0 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA39814.1 - 2.1e-06 26.6 18.8 0.00028 19.6 8.8 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Glyco_hydro_32N PF00251.20 KPA39815.1 - 1.1e-45 156.6 0.0 1.7e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KPA39815.1 - 3e-29 102.1 0.0 4.4e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 KPA39815.1 - 0.00037 19.9 0.7 0.0017 17.8 0.6 1.9 2 1 0 2 2 2 1 BNR repeat-like domain DUF4975 PF16346.5 KPA39815.1 - 0.015 15.3 0.1 0.031 14.4 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4975) BNR PF02012.20 KPA39815.1 - 2.2 8.7 11.0 0.17 12.0 0.4 4.2 4 0 0 4 4 4 0 BNR/Asp-box repeat zf-MYND PF01753.18 KPA39816.1 - 3.3e-08 33.5 8.2 5.1e-08 32.9 8.2 1.3 1 0 0 1 1 1 1 MYND finger DUF2845 PF11006.8 KPA39816.1 - 0.045 13.9 0.7 0.056 13.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) Cutinase PF01083.22 KPA39817.1 - 5.9e-23 81.7 0.4 6.9e-23 81.5 0.4 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPA39817.1 - 0.014 14.9 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.11 KPA39817.1 - 0.023 14.6 0.0 0.042 13.7 0.0 1.4 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) Thioesterase PF00975.20 KPA39817.1 - 0.023 14.8 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain PGK PF00162.19 KPA39817.1 - 0.084 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoglycerate kinase adh_short PF00106.25 KPA39818.1 - 4.1e-24 85.1 0.1 6.5e-20 71.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA39818.1 - 2.3e-11 43.7 0.0 1.1e-10 41.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA39818.1 - 4.2e-09 36.6 0.0 7.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA39818.1 - 2.3e-06 27.2 0.0 3.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPA39818.1 - 0.0015 17.8 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Chromo PF00385.24 KPA39819.1 - 5.4e-06 26.2 1.4 9.2e-06 25.5 0.1 2.1 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Oxidored_molyb PF00174.19 KPA39820.1 - 7.8e-42 142.8 0.0 1.5e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KPA39820.1 - 2.8e-21 76.0 3.2 5.2e-21 75.1 3.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain muHD PF10291.9 KPA39820.1 - 0.0089 15.5 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain HMMR_C PF15908.5 KPA39821.1 - 0.0015 18.8 0.5 0.0031 17.8 0.5 1.6 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal Mod_r PF07200.13 KPA39821.1 - 0.0017 18.5 3.6 0.0054 16.8 3.5 1.7 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein TMF_DNA_bd PF12329.8 KPA39821.1 - 0.0059 16.6 3.8 0.0059 16.6 3.8 2.0 1 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding rpo132 PF12415.8 KPA39821.1 - 0.0065 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Poxvirus DNA dependent RNA polymerase FlaC_arch PF05377.11 KPA39821.1 - 0.015 15.6 3.1 2.2 8.8 0.2 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cnn_1N PF07989.11 KPA39821.1 - 0.02 15.1 6.2 0.029 14.5 1.9 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF2730 PF10805.8 KPA39821.1 - 0.026 14.6 1.1 0.058 13.5 0.7 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2730) bZIP_1 PF00170.21 KPA39821.1 - 0.032 14.3 2.1 0.11 12.6 0.3 2.6 1 1 1 2 2 2 0 bZIP transcription factor DUF4763 PF15960.5 KPA39821.1 - 0.035 13.4 0.7 0.059 12.7 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Cep57_CLD_2 PF14197.6 KPA39821.1 - 0.048 13.8 6.8 3.1 7.9 6.8 2.5 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Fungal_TACC PF12709.7 KPA39821.1 - 0.054 14.0 1.9 0.1 13.0 0.4 2.1 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Fez1 PF06818.15 KPA39821.1 - 0.079 13.4 5.4 0.12 12.8 5.4 1.2 1 0 0 1 1 1 0 Fez1 HALZ PF02183.18 KPA39821.1 - 0.084 13.1 0.9 1.8 8.8 0.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc7 PF08317.11 KPA39821.1 - 0.13 11.1 5.5 0.19 10.6 5.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Ax_dynein_light PF10211.9 KPA39821.1 - 0.15 12.0 5.9 0.93 9.4 3.3 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4407 PF14362.6 KPA39821.1 - 0.15 11.4 2.7 0.29 10.5 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 KPA39821.1 - 0.21 11.1 2.3 0.32 10.5 2.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Tup_N PF08581.10 KPA39821.1 - 0.21 11.9 3.4 2.1 8.7 0.3 2.6 1 1 0 2 2 2 0 Tup N-terminal ATG16 PF08614.11 KPA39821.1 - 0.23 11.7 8.6 0.1 12.8 5.1 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KPA39821.1 - 0.25 11.1 6.1 0.56 10.0 5.4 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TelA PF05816.11 KPA39821.1 - 0.27 10.3 4.5 0.39 9.7 4.5 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) BBP1_C PF15272.6 KPA39821.1 - 0.35 10.7 5.1 0.57 10.0 5.1 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal YabA PF06156.13 KPA39821.1 - 0.35 11.5 1.7 1 10.0 1.7 1.8 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KPA39821.1 - 0.4 11.2 4.1 0.63 10.5 2.7 1.9 2 0 0 2 2 2 0 Cell division protein ZapB Golgin_A5 PF09787.9 KPA39821.1 - 0.41 10.1 7.9 0.59 9.6 7.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 TolA_bind_tri PF16331.5 KPA39821.1 - 0.46 10.6 3.5 0.23 11.6 1.0 1.8 2 0 0 2 2 1 0 TolA binding protein trimerisation TMPIT PF07851.13 KPA39821.1 - 0.49 9.6 0.9 0.71 9.1 0.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein Ead_Ea22 PF13935.6 KPA39821.1 - 1.2 9.8 6.2 3.6 8.2 6.2 1.8 1 1 0 1 1 1 0 Ead/Ea22-like protein DivIC PF04977.15 KPA39821.1 - 1.3 8.9 9.1 0.49 10.2 3.8 2.7 2 1 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 KPA39821.1 - 2.1 8.9 11.5 1.8 9.1 8.2 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Csm1_N PF18504.1 KPA39821.1 - 3.9 7.9 7.4 5.9 7.3 1.8 2.8 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF5595 PF18077.1 KPA39821.1 - 8 6.6 7.2 1.1 9.3 1.2 2.4 2 1 1 3 3 2 0 Domain of unknown function (DUF5595) ETRAMP PF09716.10 KPA39823.1 - 0.0099 15.9 0.3 0.02 15.0 0.0 1.7 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Glyco_transf_90 PF05686.12 KPA39823.1 - 0.06 12.2 0.0 0.077 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 90 PPP4R2 PF09184.11 KPA39823.1 - 0.069 12.7 3.3 0.091 12.3 3.3 1.1 1 0 0 1 1 1 0 PPP4R2 GFO_IDH_MocA PF01408.22 KPA39824.1 - 2e-24 86.7 0.0 4.2e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KPA39824.1 - 0.0009 19.9 0.0 0.0016 19.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain G6PD_N PF00479.22 KPA39824.1 - 0.0012 19.5 0.0 0.0022 18.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KPA39824.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KPA39825.1 - 3.9e-18 65.4 0.0 7.8e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA39825.1 - 6.5e-09 35.8 9.3 1.1e-08 35.0 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 KPA39826.1 - 8.2e-08 33.1 6.5 8.2e-08 33.1 6.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA39826.1 - 8.8e-08 32.1 0.3 1.3e-07 31.5 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA39826.1 - 0.00015 21.2 0.2 0.00025 20.4 0.2 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPA39826.1 - 0.016 14.7 0.1 0.038 13.5 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 KPA39826.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Palm_thioest PF02089.15 KPA39826.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase MFS_1 PF07690.16 KPA39827.1 - 9.4e-36 123.4 44.8 8.8e-33 113.7 44.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA39827.1 - 1.5e-13 50.0 13.5 1.5e-13 50.0 13.5 1.5 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KPA39827.1 - 0.0011 17.9 10.6 0.0011 17.9 10.6 2.8 3 0 0 3 3 3 1 MFS_1 like family Spore_III_AF PF09581.10 KPA39827.1 - 0.29 11.1 0.5 0.48 10.4 0.5 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) ACT_3 PF10000.9 KPA39828.1 - 5.5e-24 83.9 0.3 9.3e-24 83.1 0.3 1.4 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 KPA39828.1 - 8.4e-09 35.1 0.1 8.2e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 ACT domain Tannase PF07519.11 KPA39829.1 - 3.3e-75 253.8 0.2 1.3e-70 238.7 0.0 2.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KPA39829.1 - 0.00026 20.5 0.4 0.4 10.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KPA39829.1 - 0.0026 17.4 0.0 0.0072 16.0 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA39829.1 - 0.0062 15.8 0.0 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KPA39829.1 - 0.094 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Uricase PF01014.18 KPA39830.1 - 2.5e-76 254.2 0.9 1.2e-39 135.5 0.2 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.18 KPA39831.1 - 6e-42 142.8 0.0 8.6e-42 142.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 HMA PF00403.26 KPA39832.1 - 6.6e-11 42.5 0.0 1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KPA39832.1 - 3.2e-10 40.3 0.0 6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MMgT PF10270.9 KPA39832.1 - 0.052 13.9 0.0 0.08 13.3 0.0 1.3 1 0 0 1 1 1 0 Membrane magnesium transporter TPR_1 PF00515.28 KPA39833.1 - 3.3e-16 58.3 4.6 2e-07 30.5 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPA39833.1 - 4.4e-14 51.4 5.5 1.4e-05 24.8 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KPA39833.1 - 5e-11 41.9 0.5 1.7e-05 24.7 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPA39833.1 - 7.9e-11 42.1 0.2 1e-06 28.9 0.1 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KPA39833.1 - 3.7e-08 33.5 0.1 0.12 13.1 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.24 KPA39833.1 - 8.9e-08 32.0 0.5 1.7e-07 31.1 0.5 1.4 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.6 KPA39833.1 - 3e-07 30.0 2.9 2.4e-05 23.9 0.2 3.8 2 1 1 3 3 3 1 TPR repeat TPR_7 PF13176.6 KPA39833.1 - 3.4e-07 29.8 0.1 4e-05 23.4 0.0 3.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KPA39833.1 - 0.00017 21.6 0.1 0.57 10.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPA39833.1 - 0.0012 19.1 0.1 1.1 9.8 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPA39833.1 - 0.0013 19.3 0.9 0.007 17.0 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPA39833.1 - 0.036 14.9 0.2 0.34 11.8 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KPA39833.1 - 0.067 13.1 2.0 0.57 10.1 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 KPA39833.1 - 0.12 11.1 0.1 0.52 9.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) tRNA-synt_1c PF00749.21 KPA39834.1 - 3.8e-82 275.7 0.0 5.7e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 KPA39835.1 - 1.5e-35 122.5 0.2 2.2e-35 122.0 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KPA39835.1 - 5.2e-24 84.1 5.0 5.2e-24 84.1 5.0 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KPA39835.1 - 1e-13 51.4 19.0 2.1e-13 50.4 19.0 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KPA39835.1 - 0.0016 18.3 10.7 0.15 12.0 0.7 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein LTXXQ PF07813.12 KPA39835.1 - 0.048 14.4 0.6 0.095 13.4 0.6 1.5 1 0 0 1 1 1 0 LTXXQ motif family protein Malate_DH PF12434.8 KPA39835.1 - 0.089 12.8 0.1 0.31 11.1 0.1 1.9 1 0 0 1 1 1 0 Malate dehydrogenase enzyme HypA PF01155.19 KPA39835.1 - 0.18 11.9 8.5 3.4 7.7 0.8 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 KPA39835.1 - 0.53 9.5 3.3 3.4 6.9 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Mt_ATP-synt_D PF05873.12 KPA39835.1 - 0.58 10.0 5.1 11 5.8 0.0 2.2 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) TackOD1 PF18551.1 KPA39835.1 - 3.4 7.3 8.6 4.4 6.9 1.8 2.2 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 zf-RING_10 PF16685.5 KPA39835.1 - 8.3 6.6 12.2 2.1 8.5 2.4 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 EAP30 PF04157.16 KPA39836.1 - 3.9e-72 242.4 0.0 4.4e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Mpv17_PMP22 PF04117.12 KPA39837.1 - 2.2e-09 37.4 3.2 1e-08 35.3 2.5 2.1 1 1 1 2 2 2 1 Mpv17 / PMP22 family DUF2457 PF10446.9 KPA39838.1 - 3.3 6.7 6.4 4.4 6.4 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SH3_1 PF00018.28 KPA39839.1 - 3e-05 23.5 0.0 5.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPA39839.1 - 0.043 13.7 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain ELFV_dehydrog PF00208.21 KPA39840.1 - 8.8e-65 218.8 0.0 1.4e-64 218.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KPA39840.1 - 7.9e-21 73.4 0.0 2.3e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KPA39840.1 - 0.0015 18.4 0.0 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Tom22 PF04281.13 KPA39841.1 - 8.6e-51 171.4 0.0 1e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 A_deaminase PF00962.22 KPA39842.1 - 4.5e-31 108.4 0.0 5.7e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Dynamin_N PF00350.23 KPA39843.1 - 1.9e-18 67.1 0.7 3.2e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KPA39843.1 - 1.8e-10 40.9 0.0 8.7e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPA39843.1 - 2.7e-06 27.0 1.5 4.1e-05 23.2 0.9 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPA39843.1 - 0.0082 16.1 0.4 2.9 7.8 0.1 2.7 2 1 0 2 2 2 1 RsgA GTPase TsaE PF02367.17 KPA39843.1 - 0.03 14.3 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FlaC_arch PF05377.11 KPA39843.1 - 0.033 14.6 0.4 9 6.8 0.4 3.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Roc PF08477.13 KPA39843.1 - 0.037 14.3 0.3 1.3 9.2 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KPA39843.1 - 0.039 13.5 0.7 0.45 10.1 0.7 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KPA39843.1 - 0.059 13.9 0.0 0.31 11.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain YliH PF10799.8 KPA39843.1 - 0.07 13.1 0.1 2.4 8.1 0.0 3.0 2 1 1 3 3 3 0 Biofilm formation protein (YliH/bssR) PMEI PF04043.15 KPA39843.1 - 0.076 13.4 0.1 0.31 11.4 0.1 2.0 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor IIGP PF05049.13 KPA39843.1 - 0.077 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF2408 PF10303.9 KPA39843.1 - 0.084 13.4 0.6 0.34 11.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Sigma54_activat PF00158.26 KPA39843.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 KPA39843.1 - 0.12 12.1 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SYF2 PF08231.12 KPA39843.1 - 0.38 11.2 1.8 0.88 10.0 0.6 2.1 2 0 0 2 2 2 0 SYF2 splicing factor End3 PF12761.7 KPA39843.1 - 7.7 6.6 9.3 0.21 11.7 1.3 2.5 3 1 1 4 4 3 0 Actin cytoskeleton-regulatory complex protein END3 Snf7 PF03357.21 KPA39844.1 - 1.2e-35 122.6 14.5 1.2e-35 122.6 14.5 1.4 2 0 0 2 2 2 1 Snf7 CaMBD PF02888.16 KPA39844.1 - 0.07 13.3 0.6 0.07 13.3 0.6 2.1 2 0 0 2 2 2 0 Calmodulin binding domain Ist1 PF03398.14 KPA39844.1 - 0.091 12.7 5.7 0.16 11.9 5.7 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DSBA PF01323.20 KPA39844.1 - 0.32 10.8 4.1 0.65 9.7 4.1 1.6 1 1 0 1 1 1 0 DSBA-like thioredoxin domain RHH_8 PF17723.1 KPA39844.1 - 0.4 10.9 3.3 0.86 9.8 0.4 2.4 1 1 2 3 3 3 0 Ribbon-Helix-Helix transcriptional regulator family PspA_IM30 PF04012.12 KPA39844.1 - 0.56 9.7 12.6 1.3 8.5 2.4 2.1 1 1 0 2 2 2 0 PspA/IM30 family Exonuc_VII_L PF02601.15 KPA39844.1 - 0.84 9.1 5.8 1.5 8.3 5.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 KPA39844.1 - 1.5 8.9 8.6 0.36 10.9 1.8 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PP2C PF00481.21 KPA39846.1 - 4e-62 210.2 0.1 3.2e-49 167.9 0.1 2.5 1 1 1 2 2 2 2 Protein phosphatase 2C DUF4705 PF15788.5 KPA39847.1 - 0.016 15.4 0.0 2.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4705) Homeobox_KN PF05920.11 KPA39850.1 - 6.5e-17 61.2 0.0 1.7e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KPA39850.1 - 4.8e-09 35.9 0.4 9.9e-09 34.9 0.4 1.5 1 0 0 1 1 1 1 Homeodomain zf-C2H2_2 PF12756.7 KPA39850.1 - 0.0039 17.5 4.5 3.4 8.1 0.5 3.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KPA39850.1 - 0.012 16.1 2.4 0.012 16.1 2.4 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type Homez PF11569.8 KPA39850.1 - 0.019 14.4 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-C2H2_4 PF13894.6 KPA39850.1 - 0.02 15.7 2.3 0.02 15.7 2.3 5.3 7 0 0 7 7 7 0 C2H2-type zinc finger zf-SNAP50_C PF12251.8 KPA39850.1 - 0.39 10.4 2.7 1.7 8.3 0.5 2.5 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal Zn_clus PF00172.18 KPA39850.1 - 1 9.5 10.7 0.19 11.9 5.2 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.7 KPA39850.1 - 1 9.8 9.1 5.5 7.5 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PALP PF00291.25 KPA39851.1 - 1.2e-58 198.8 0.3 2.3e-58 197.9 0.3 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 KPA39851.1 - 1.4e-29 103.3 0.5 2.5e-29 102.4 0.5 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPA39851.1 - 2.4e-14 53.1 0.1 8.8e-14 51.3 0.1 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KPA39851.1 - 0.041 13.6 0.3 0.076 12.7 0.3 1.4 1 0 0 1 1 1 0 Peptidase family M28 MFS_1 PF07690.16 KPA39852.1 - 3.2e-10 39.5 35.1 4.5e-10 39.0 34.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KPA39852.1 - 1.3e-06 28.2 7.0 1.3e-06 28.2 7.0 3.3 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 Arylesterase PF01731.20 KPA39853.1 - 2.9e-06 27.4 0.4 6.7e-06 26.2 0.4 1.6 1 0 0 1 1 1 1 Arylesterase Pectate_lyase22 PF14583.6 KPA39853.1 - 0.0069 15.1 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Oligogalacturonate lyase Gin PF10764.9 KPA39854.1 - 0.034 14.1 0.3 0.054 13.5 0.3 1.3 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin OSTMP1 PF09777.9 KPA39854.1 - 0.035 13.5 0.1 0.043 13.2 0.1 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Zn_clus PF00172.18 KPA39855.1 - 9.6e-07 28.8 6.2 1.8e-06 28.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA39855.1 - 1.3e-05 24.2 0.2 0.00082 18.3 0.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain CBM9_2 PF16011.5 KPA39856.1 - 0.0004 20.1 1.3 0.00079 19.2 1.3 1.5 1 1 0 1 1 1 1 Carbohydrate-binding family 9 SPC25 PF06703.11 KPA39858.1 - 0.044 13.6 1.3 0.082 12.7 1.3 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF1345 PF07077.11 KPA39858.1 - 0.15 11.7 8.8 0.038 13.7 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF4418 PF14387.6 KPA39858.1 - 0.7 10.1 6.5 2.3 8.5 6.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4418) EamA PF00892.20 KPA39858.1 - 1.2 9.3 13.1 1.8 8.7 7.6 2.1 2 0 0 2 2 2 0 EamA-like transporter family Vma12 PF11712.8 KPA39858.1 - 4.4 7.4 9.8 0.47 10.5 4.3 2.1 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Sugar_tr PF00083.24 KPA39859.1 - 1.1e-66 225.6 13.7 2e-66 224.7 13.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA39859.1 - 7.5e-16 58.0 45.7 7.9e-14 51.3 24.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 KPA39860.1 - 1.6e-09 38.2 0.5 7.6e-06 26.4 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA39860.1 - 2.5e-09 37.5 0.8 0.0048 17.4 0.0 4.6 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA39860.1 - 2.6e-06 27.6 1.3 0.37 11.2 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA39860.1 - 7.6e-05 22.8 0.7 0.17 12.5 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat TPR_7 PF13176.6 KPA39860.1 - 0.0032 17.4 0.1 0.042 13.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Ank PF00023.30 KPA39860.1 - 0.19 12.3 8.4 12 6.5 0.0 4.5 5 0 0 5 5 5 0 Ankyrin repeat Zn_clus PF00172.18 KPA39861.1 - 4.1e-09 36.4 9.3 6.5e-09 35.8 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA39861.1 - 0.0017 17.4 0.1 0.0037 16.3 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain RskA PF10099.9 KPA39861.1 - 2.9 8.1 11.6 8.2 6.7 1.8 2.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.13 KPA39861.1 - 3 7.7 15.7 0.11 12.5 7.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Protoglobin PF11563.8 KPA39862.1 - 8.1e-60 201.3 0.1 9.5e-60 201.1 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Glyco_transf_20 PF00982.21 KPA39863.1 - 6.8e-150 499.9 0.0 9.2e-150 499.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KPA39863.1 - 2.8e-70 236.1 0.0 6.5e-70 234.9 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase Glyco_trans_1_2 PF13524.6 KPA39863.1 - 0.041 14.3 0.0 0.14 12.6 0.0 2.0 1 0 0 1 1 1 0 Glycosyl transferases group 1 Zn_clus PF00172.18 KPA39864.1 - 3.4e-06 27.1 9.9 7.2e-06 26.0 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA39864.1 - 3.9e-05 22.8 0.2 7.9e-05 21.8 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPA39865.1 - 6.9e-06 26.2 11.6 0.0029 18.0 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPA39865.1 - 0.0003 21.1 3.8 0.0003 21.1 3.8 2.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPA39865.1 - 0.00046 20.8 11.0 0.08 13.8 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger DUF4407 PF14362.6 KPA39865.1 - 0.21 10.9 3.2 0.31 10.4 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-H2C2_5 PF13909.6 KPA39865.1 - 1.8 8.4 5.6 2.6 7.9 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Abhydrolase_2 PF02230.16 KPA39866.1 - 7.9e-62 208.9 0.0 9.5e-62 208.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KPA39866.1 - 2.3e-09 36.9 0.2 2.8e-05 23.5 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPA39866.1 - 1.1e-08 34.9 0.0 4.7e-06 26.2 0.0 2.7 3 0 0 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.13 KPA39866.1 - 1.1e-07 31.8 0.0 9.2e-07 28.7 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KPA39866.1 - 1.8e-06 28.7 0.3 0.00049 20.8 0.1 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KPA39866.1 - 5.4e-06 26.4 0.0 0.11 12.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KPA39866.1 - 3.9e-05 23.3 0.0 8.8e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KPA39866.1 - 6.2e-05 22.8 0.3 0.29 10.7 0.0 3.1 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KPA39866.1 - 0.0018 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DUF2920 PF11144.8 KPA39866.1 - 0.014 14.6 0.0 0.16 11.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) BAAT_C PF08840.11 KPA39866.1 - 0.11 12.4 0.0 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.8 KPA39866.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LIP PF03583.14 KPA39866.1 - 0.22 10.8 0.1 4.1 6.6 0.0 2.3 1 1 0 2 2 2 0 Secretory lipase AXE1 PF05448.12 KPA39866.1 - 0.24 10.1 0.1 0.69 8.5 0.1 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) IMD PF08397.11 KPA39867.1 - 1.9e-05 24.2 4.2 0.00029 20.3 4.2 2.1 1 1 0 1 1 1 1 IRSp53/MIM homology domain FliD_N PF02465.18 KPA39867.1 - 0.19 12.4 0.9 5.6 7.7 0.3 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Spectrin PF00435.21 KPA39867.1 - 3.5 8.2 5.9 1.2 9.7 1.6 2.4 2 0 0 2 2 2 0 Spectrin repeat LigB PF02900.18 KPA39869.1 - 1.9e-36 125.5 0.3 2.5e-36 125.2 0.3 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PGA_cap PF09587.10 KPA39869.1 - 0.0072 15.8 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 1 Bacterial capsule synthesis protein PGA_cap RTC PF01137.21 KPA39870.1 - 5.5e-51 172.9 0.0 7.9e-51 172.4 0.0 1.3 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Glyco_hydro_61 PF03443.14 KPA39874.1 - 9.1e-56 189.0 0.2 1.2e-55 188.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 dbPDZ_assoc PF16610.5 KPA39874.1 - 0.027 14.7 6.5 1.3 9.3 5.9 2.3 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 Serglycin PF04360.12 KPA39874.1 - 0.05 13.6 0.1 0.088 12.8 0.1 1.4 1 0 0 1 1 1 0 Serglycin ATP-grasp_4 PF13535.6 KPA39874.1 - 0.082 12.5 0.2 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain DUF4136 PF13590.6 KPA39874.1 - 0.092 13.3 0.0 0.12 13.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4136) Sec63 PF02889.16 KPA39876.1 - 1.2e-136 453.9 0.0 1.9e-79 266.5 0.2 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KPA39876.1 - 9.1e-51 172.1 0.1 6.9e-27 94.3 0.4 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KPA39876.1 - 2.2e-22 79.8 0.0 2.2e-10 40.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPA39876.1 - 3.2e-16 59.6 0.2 1.5e-06 28.5 0.0 4.7 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KPA39876.1 - 2e-07 31.3 0.2 0.04 14.2 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KPA39876.1 - 5e-07 29.6 0.5 0.0058 16.4 0.2 3.1 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KPA39876.1 - 2.4e-05 24.7 0.4 0.004 17.5 0.4 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KPA39876.1 - 0.0011 19.4 0.1 2.7 8.4 0.0 4.4 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 KPA39876.1 - 0.0042 17.3 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain T2SSE PF00437.20 KPA39876.1 - 0.017 14.2 0.0 1.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 KPA39876.1 - 0.046 14.1 0.0 1.5 9.1 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 KPA39876.1 - 0.064 12.7 0.6 20 4.5 0.1 3.6 4 0 0 4 4 4 0 Bacterial TniB protein Synaptobrevin PF00957.21 KPA39877.1 - 3.5e-14 52.4 0.5 5.3e-14 51.8 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KPA39877.1 - 2.3e-13 50.0 0.0 4.7e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 Regulated-SNARE-like domain DUF16 PF01519.16 KPA39877.1 - 0.17 12.4 1.7 0.24 11.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 Profilin PF00235.19 KPA39879.1 - 3.9e-44 150.0 0.6 4.3e-44 149.8 0.6 1.0 1 0 0 1 1 1 1 Profilin Got1 PF04178.12 KPA39880.1 - 1.7e-13 51.0 13.8 2.1e-13 50.7 13.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family YL1_C PF08265.11 KPA39881.1 - 1.1e-14 53.8 0.1 1.8e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DASH_Dad4 PF08650.10 KPA39882.1 - 2.6e-33 113.8 7.8 2.8e-33 113.7 7.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 KPA39882.1 - 0.036 14.2 0.5 0.041 14.0 0.5 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Actin PF00022.19 KPA39883.1 - 4.8e-55 186.8 0.0 4.2e-52 177.1 0.0 2.5 1 1 0 1 1 1 1 Actin HEM4 PF02602.15 KPA39884.1 - 4.3e-40 137.5 0.0 5.5e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Arylsulfotran_N PF17425.2 KPA39884.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain TLD PF07534.16 KPA39885.1 - 5.9e-25 88.1 0.0 2.7e-12 47.1 0.0 2.2 2 0 0 2 2 2 2 TLD Pkinase PF00069.25 KPA39886.1 - 2.5e-68 230.3 0.0 3.4e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA39886.1 - 4.4e-32 111.4 0.0 5.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPA39886.1 - 0.00016 21.1 0.3 0.00026 20.4 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KPA39886.1 - 0.0014 17.7 0.5 0.0026 16.7 0.5 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KPA39886.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KPA39886.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KPA39886.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.11 KPA39886.1 - 0.094 13.0 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.19 KPA39886.1 - 0.13 12.0 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain RabGAP-TBC PF00566.18 KPA39887.1 - 3e-50 170.8 0.0 6.6e-50 169.7 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 KPA39888.1 - 1.6e-34 117.5 0.3 4.3e-16 58.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPA39888.1 - 1.7e-11 44.0 0.2 0.00012 22.1 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KPA39888.1 - 9e-05 22.4 0.1 0.26 11.3 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KPA39888.1 - 0.033 14.2 0.1 12 6.0 0.0 2.8 2 0 0 2 2 2 0 RNA binding motif HECT PF00632.25 KPA39889.1 - 1.6e-95 320.1 0.0 2.2e-95 319.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KPA39889.1 - 1.3e-34 117.9 24.7 6.9e-13 48.4 6.3 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KPA39889.1 - 1.1e-19 70.6 0.0 3.3e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.22 KPA39890.1 - 9.7e-17 60.6 0.0 1.6e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPV_P10 PF05531.12 KPA39890.1 - 0.021 15.3 0.2 0.04 14.4 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Nup35_RRM_2 PF14605.6 KPA39890.1 - 0.036 14.1 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KPA39890.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif Spc7 PF08317.11 KPA39890.1 - 0.12 11.3 9.4 0.16 10.8 9.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PRKG1_interact PF15898.5 KPA39890.1 - 0.19 12.7 9.8 0.28 12.1 9.8 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain EMP24_GP25L PF01105.24 KPA39890.1 - 0.19 11.7 4.0 0.25 11.3 4.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD V_ATPase_I PF01496.19 KPA39890.1 - 0.22 9.4 4.6 0.26 9.1 4.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KPA39890.1 - 0.35 10.9 3.9 0.56 10.3 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Med9 PF07544.13 KPA39890.1 - 0.5 10.5 4.1 0.75 9.9 3.9 1.5 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.15 KPA39890.1 - 0.6 9.9 6.2 1.1 9.1 6.2 1.3 1 0 0 1 1 1 0 Septum formation initiator PA26 PF04636.13 KPA39890.1 - 0.63 8.9 3.1 0.74 8.7 3.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CPSF100_C PF13299.6 KPA39890.1 - 1 9.5 5.7 1.4 9.1 5.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3450 PF11932.8 KPA39890.1 - 3.3 6.9 9.9 4.4 6.5 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pannexin_like PF12534.8 KPA39890.1 - 4.4 6.3 4.9 5.7 5.9 4.9 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF4588 PF15251.6 KPA39891.1 - 1.3e-06 28.4 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) SNF2_N PF00176.23 KPA39892.1 - 6.3e-76 255.3 0.1 1.1e-75 254.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KPA39892.1 - 8.3e-42 141.8 1.1 8.3e-42 141.8 1.1 2.4 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KPA39892.1 - 1.3e-35 122.5 5.6 1.3e-35 122.5 5.6 4.5 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 KPA39892.1 - 3.2e-18 66.1 0.1 1.6e-17 63.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA39892.1 - 1e-10 41.9 0.0 5.6e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KPA39892.1 - 6.5e-05 22.2 0.0 0.00021 20.6 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KPA39892.1 - 0.00018 21.3 0.0 0.00065 19.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KPA39892.1 - 0.00068 19.4 0.0 0.0031 17.2 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase Myb_DNA-binding PF00249.31 KPA39892.1 - 0.0056 16.8 0.0 3.6 7.9 0.0 3.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain ERCC3_RAD25_C PF16203.5 KPA39892.1 - 0.0083 15.4 0.1 0.017 14.3 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 KPA39893.1 - 9.7e-23 80.0 2.2 7.6e-08 32.9 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA39893.1 - 2.7e-15 56.4 0.0 0.0027 18.0 0.0 4.9 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KPA39893.1 - 0.00043 19.4 0.0 0.074 12.1 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 KPA39893.1 - 0.0018 18.2 0.1 2.2 8.1 0.0 3.2 1 1 4 5 5 5 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KPA39893.1 - 0.005 16.2 0.0 0.026 13.8 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain PQQ_2 PF13360.6 KPA39893.1 - 0.022 14.3 0.0 0.36 10.4 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain Nup160 PF11715.8 KPA39893.1 - 0.092 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 FTHFS PF01268.19 KPA39894.1 - 4.6e-251 833.9 0.3 4.6e-251 833.9 0.3 1.7 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KPA39894.1 - 4.4e-67 224.4 0.7 4.4e-67 224.4 0.7 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KPA39894.1 - 9.2e-39 132.3 0.2 1.9e-38 131.3 0.2 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Helicase_C_4 PF13871.6 KPA39894.1 - 0.041 13.6 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue Fungal_trans PF04082.18 KPA39895.1 - 3.4e-06 26.3 0.2 6.5e-06 25.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA39895.1 - 1.7e-05 24.8 8.4 1.7e-05 24.8 8.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF92 PF01940.16 KPA39896.1 - 3.2e-87 291.8 0.1 3.8e-87 291.6 0.1 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Gln-synt_C PF00120.24 KPA39897.1 - 6.5e-17 61.6 0.0 1.8e-12 46.9 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KPA39897.1 - 5.2e-13 48.5 0.0 8.4e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Pyridoxal_deC PF00282.19 KPA39900.1 - 2.6e-27 95.5 0.0 3.2e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KPA39900.1 - 9.2e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KPA39900.1 - 0.002 17.3 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II ACD PF16671.5 KPA39900.1 - 0.029 12.7 0.0 0.044 12.1 0.0 1.2 1 0 0 1 1 1 0 Actin cross-linking domain Aminotran_5 PF00266.19 KPA39900.1 - 0.079 11.9 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Cyt-b5 PF00173.28 KPA39901.1 - 1.1e-19 70.3 0.2 1.3e-19 70.1 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyltransferase PF01553.21 KPA39902.1 - 2.5e-28 98.4 0.0 3.5e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KPA39902.1 - 5.4e-13 48.8 0.3 9.6e-13 48.0 0.3 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 KPA39903.1 - 8.8e-46 156.4 0.0 2.1e-45 155.2 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KPA39903.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PLA2_B PF01735.18 KPA39904.1 - 8.9e-183 608.2 0.2 1e-182 608.0 0.2 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Pribosyl_synth PF14572.6 KPA39905.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain GFO_IDH_MocA PF01408.22 KPA39906.1 - 7.4e-29 101.0 0.0 2.3e-28 99.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPA39906.1 - 2e-10 40.7 0.0 4.8e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KPA39906.1 - 4.4e-05 24.1 0.0 0.00011 22.9 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KPA39906.1 - 5.3e-05 23.6 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KPA39906.1 - 0.022 15.0 0.0 0.058 13.7 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CFEM PF05730.11 KPA39907.1 - 5.7e-11 42.3 9.7 1.1e-10 41.4 9.7 1.5 1 0 0 1 1 1 1 CFEM domain Peptidase_C34 PF05413.11 KPA39907.1 - 0.081 13.2 1.7 0.12 12.6 1.7 1.3 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase LIDHydrolase PF10230.9 KPA39908.1 - 2.1e-57 194.7 0.0 2.4e-57 194.5 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KPA39908.1 - 4.8e-05 24.1 0.1 6.2e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA39908.1 - 0.0046 16.2 0.0 0.022 14.0 0.0 2.2 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA39908.1 - 0.005 16.5 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M28 PF04389.17 KPA39909.1 - 2.6e-36 125.2 0.0 5.1e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KPA39909.1 - 0.0083 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KPA39909.1 - 0.21 10.6 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase SF1-HH PF16275.5 KPA39910.1 - 2.2e-43 147.2 1.2 2.2e-43 147.2 1.2 1.8 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KPA39910.1 - 1.9e-11 43.5 11.3 1.3e-05 25.1 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KPA39910.1 - 1.7e-07 31.0 0.1 3.2e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 KPA39910.1 - 8e-07 28.9 7.0 0.00046 20.1 3.5 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KPA39910.1 - 0.00014 21.6 7.5 0.043 13.6 0.5 2.8 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KPA39910.1 - 0.0014 18.3 5.0 0.55 10.0 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 KPA39910.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 KPA39910.1 - 0.26 11.4 2.2 0.54 10.4 2.2 1.5 1 0 0 1 1 1 0 PHD-finger Prim_Zn_Ribbon PF08273.12 KPA39910.1 - 1.4 9.3 6.9 0.18 12.1 2.3 1.9 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase eIF3g PF12353.8 KPA39910.1 - 1.9 8.9 7.3 3.5 8.0 0.5 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G MFS_1 PF07690.16 KPA39911.1 - 3.4e-66 223.6 94.8 2.1e-35 122.3 56.8 3.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA39911.1 - 2.8e-16 59.1 24.0 2e-15 56.3 24.1 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPA39911.1 - 1.8e-14 53.5 6.5 1.8e-14 53.5 6.5 4.6 3 2 1 4 4 4 1 Sugar (and other) transporter MFS_4 PF06779.14 KPA39911.1 - 1.9e-07 30.7 1.7 1.9e-07 30.7 1.7 4.0 4 0 0 4 4 4 2 Uncharacterised MFS-type transporter YbfB HET PF06985.11 KPA39912.1 - 1.8e-11 44.6 4.2 5.5e-09 36.5 4.2 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lipase_3 PF01764.25 KPA39913.1 - 1.2e-20 73.8 0.0 2.6e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Zn_clus PF00172.18 KPA39914.1 - 3.7e-10 39.7 12.3 6.8e-10 38.9 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA39914.1 - 1.8e-07 30.5 1.2 3.4e-07 29.6 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KPA39915.1 - 6.4e-74 248.0 3.1 6.4e-74 248.0 3.1 1.7 1 1 1 2 2 2 1 RTA1 like protein Cation_ATPase_C PF00689.21 KPA39915.1 - 0.12 12.0 12.8 0.042 13.5 2.0 2.5 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Pkinase PF00069.25 KPA39917.1 - 5.5e-12 45.6 0.0 4.2e-11 42.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA39917.1 - 6.1e-08 32.3 0.0 7.8e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Lon_C PF05362.13 KPA39918.1 - 8.9e-66 221.3 0.0 1.5e-65 220.6 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KPA39918.1 - 2.2e-30 106.1 1.0 2.9e-30 105.7 0.1 1.7 2 0 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KPA39918.1 - 3.2e-21 76.1 0.0 7.6e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KPA39918.1 - 5.7e-07 29.6 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KPA39918.1 - 2.1e-06 28.0 0.0 6.4e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 KPA39918.1 - 5.8e-06 26.2 0.0 1.9e-05 24.5 0.0 1.9 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 KPA39918.1 - 2.4e-05 24.7 0.0 0.00029 21.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KPA39918.1 - 0.00015 21.6 0.1 0.00094 19.0 0.0 2.4 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 KPA39918.1 - 0.00026 20.0 0.0 0.00057 18.9 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 KPA39918.1 - 0.00059 20.3 1.0 0.0034 17.8 0.1 2.6 2 1 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.6 KPA39918.1 - 0.0038 17.8 0.2 0.063 13.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KPA39918.1 - 0.019 14.7 0.0 0.07 12.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 KPA39918.1 - 0.027 14.5 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KPA39918.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KPA39918.1 - 0.054 13.4 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 KPA39918.1 - 0.059 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DNTTIP1_dimer PF18192.1 KPA39918.1 - 0.063 13.6 1.1 4.8 7.6 0.2 3.3 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain NTPase_1 PF03266.15 KPA39918.1 - 0.071 13.0 0.2 1.6 8.6 0.0 2.6 1 1 1 2 2 2 0 NTPase AAA_7 PF12775.7 KPA39918.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KPA39918.1 - 0.14 12.4 1.2 22 5.2 0.0 3.3 3 1 0 3 3 3 0 AAA domain AbrB_C PF18277.1 KPA39918.1 - 0.19 11.4 0.6 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 AbrB C-terminal domain ABC_tran PF00005.27 KPA39918.1 - 1.2 9.6 4.8 1 9.9 0.1 2.8 3 0 0 3 3 3 0 ABC transporter tRNA-synt_1c PF00749.21 KPA39919.1 - 0.014 14.3 0.6 0.028 13.3 0.2 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Presenilin PF01080.17 KPA39919.1 - 5.5 5.7 7.4 7.2 5.3 7.4 1.1 1 0 0 1 1 1 0 Presenilin KH_1 PF00013.29 KPA39920.1 - 2.4e-29 101.0 3.5 9.9e-08 31.7 0.0 7.1 7 0 0 7 7 7 6 KH domain HAD_2 PF13419.6 KPA39922.1 - 4.8e-12 46.3 0.0 7e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA39922.1 - 1.4e-10 41.9 0.0 1.1e-09 38.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA39922.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Med21 PF11221.8 KPA39923.1 - 1.4e-46 158.3 5.8 1.6e-46 158.2 5.8 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 KPA39923.1 - 0.003 17.6 6.9 0.0063 16.6 2.1 3.3 1 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 HMMR_N PF15905.5 KPA39923.1 - 0.0072 15.8 2.4 0.0096 15.4 2.4 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 KPA39923.1 - 0.015 14.7 5.2 0.5 9.7 0.0 2.2 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4455 PF14643.6 KPA39923.1 - 0.065 11.9 3.8 0.024 13.3 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) T3SS_needle_E PF08988.10 KPA39923.1 - 0.15 12.2 2.4 1.3 9.3 0.4 2.3 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle TMF_DNA_bd PF12329.8 KPA39923.1 - 0.24 11.4 9.3 3.3 7.8 9.3 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 KPA39923.1 - 0.4 10.8 3.8 0.88 9.7 1.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Sec62 PF03839.16 KPA39924.1 - 2.6e-68 229.8 0.7 2.6e-68 229.8 0.7 1.5 2 0 0 2 2 2 1 Translocation protein Sec62 Corona_M PF01635.18 KPA39924.1 - 0.91 8.8 4.7 1.4 8.2 4.7 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Acetyltransf_1 PF00583.25 KPA39925.1 - 5.2e-09 36.4 0.0 6.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA39925.1 - 5.3e-08 32.9 0.0 7.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA39925.1 - 6e-08 32.5 0.1 9.9e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KPA39925.1 - 6.2e-06 26.6 0.0 8.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA39925.1 - 0.082 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PLDc_2 PF13091.6 KPA39926.1 - 1.5e-15 57.3 0.0 1.1e-06 28.5 0.0 3.6 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KPA39926.1 - 1.1e-11 44.4 2.1 3.5e-05 23.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KPA39926.1 - 0.083 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Thioredoxin PF00085.20 KPA39927.1 - 3.3e-42 142.7 1.4 2e-25 88.7 0.1 4.1 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KPA39927.1 - 2e-12 47.4 0.2 7.5e-08 32.5 0.0 4.1 5 0 0 5 5 5 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KPA39927.1 - 2.6e-08 34.3 3.6 0.0014 19.0 0.1 3.0 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KPA39927.1 - 3.7e-06 27.2 3.1 0.13 12.6 0.0 4.8 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_3 PF13192.6 KPA39927.1 - 0.00018 21.5 0.5 0.0045 17.0 0.0 3.2 4 0 0 4 4 4 1 Thioredoxin domain OST3_OST6 PF04756.13 KPA39927.1 - 0.0024 17.3 1.6 2.6 7.3 0.0 2.9 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family TraF PF13728.6 KPA39927.1 - 0.0033 17.3 0.0 0.0033 17.3 0.0 3.3 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 KPA39927.1 - 0.0042 16.8 0.1 0.38 10.4 0.0 2.9 1 1 1 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 KPA39927.1 - 0.0048 16.8 2.9 0.39 10.6 0.1 3.7 4 0 0 4 4 4 1 AhpC/TSA family UBN_AB PF14075.6 KPA39927.1 - 0.015 15.0 1.3 0.033 13.9 1.3 1.5 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Thioredoxin_7 PF13899.6 KPA39927.1 - 0.018 15.2 1.8 1.6 8.9 0.1 3.0 3 0 0 3 3 3 0 Thioredoxin-like 1-cysPrx_C PF10417.9 KPA39927.1 - 0.045 13.6 0.9 7.4 6.5 0.6 2.7 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin Tyr-DNA_phospho PF06087.12 KPA39928.1 - 1.5e-159 531.5 0.0 1.7e-159 531.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KPA39928.1 - 0.089 12.7 0.2 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 PLD-like domain MatE PF01554.18 KPA39929.1 - 3.5e-53 179.5 28.1 1.5e-32 112.5 9.4 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KPA39929.1 - 0.002 18.2 10.0 0.002 18.2 10.0 3.4 3 1 2 5 5 5 2 Polysaccharide biosynthesis C-terminal domain Actin PF00022.19 KPA39930.1 - 1e-15 57.3 0.0 5.4e-14 51.6 0.0 2.6 2 0 0 2 2 2 1 Actin DUF1387 PF07139.11 KPA39930.1 - 0.042 13.6 18.6 0.082 12.6 18.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) HA2 PF04408.23 KPA39930.1 - 0.43 10.9 2.9 0.98 9.7 2.9 1.6 1 0 0 1 1 1 0 Helicase associated domain (HA2) FtsA PF14450.6 KPA39930.1 - 0.49 10.8 5.1 0.95 9.9 5.1 1.7 1 1 0 1 1 1 0 Cell division protein FtsA Membralin PF09746.9 KPA39930.1 - 2.2 7.3 4.3 3.4 6.6 4.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein Dynactin_p62 PF05502.13 KPA39930.1 - 2.2 7.0 8.5 16 4.1 0.0 2.2 2 0 0 2 2 2 0 Dynactin p62 family PA26 PF04636.13 KPA39930.1 - 3.7 6.4 4.8 5.9 5.7 4.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF1840 PF08895.11 KPA39930.1 - 4.8 7.6 8.1 14 6.1 8.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) U79_P34 PF03064.16 KPA39930.1 - 5 6.4 14.0 9.2 5.6 14.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3915 PF13054.6 KPA39930.1 - 6 6.9 10.2 14 5.7 10.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Ysc84 PF04366.12 KPA39931.1 - 5.5e-29 100.5 0.0 9.1e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator PBP_N PF17093.5 KPA39931.1 - 0.42 10.9 3.9 2 8.7 3.2 2.5 1 1 1 2 2 2 0 Penicillin-binding protein N-terminus Glyco_hydro_76 PF03663.14 KPA39932.1 - 2.7e-46 158.8 10.9 7.8e-46 157.3 10.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 TFCD_C PF12612.8 KPA39932.1 - 4.7e-26 91.8 0.4 1.4e-25 90.3 0.4 1.8 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal Glyco_hydro_88 PF07470.13 KPA39932.1 - 1e-05 24.8 2.4 0.003 16.7 0.0 3.1 1 1 2 3 3 3 2 Glycosyl Hydrolase Family 88 HEAT_2 PF13646.6 KPA39932.1 - 0.0006 20.2 2.9 0.39 11.1 0.1 4.3 4 0 0 4 4 4 2 HEAT repeats Glyco_hydro_127 PF07944.12 KPA39932.1 - 0.013 14.0 0.0 0.037 12.5 0.0 1.6 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 HEAT PF02985.22 KPA39932.1 - 1.9 9.0 10.9 3.1 8.3 0.0 5.2 7 0 0 7 7 7 0 HEAT repeat SH3_9 PF14604.6 KPA39933.1 - 3e-07 30.2 0.0 6.3e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain zf-C2H2_6 PF13912.6 KPA39933.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Anoctamin PF04547.12 KPA39934.1 - 7.6e-112 374.4 8.3 9.7e-112 374.1 8.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Metallophos PF00149.28 KPA39935.1 - 3.4e-15 57.1 3.8 6.3e-15 56.2 3.8 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPA39935.1 - 0.00013 22.2 2.0 0.0011 19.2 2.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WSC PF01822.19 KPA39936.1 - 1.5e-13 50.7 6.5 3.6e-13 49.5 6.5 1.7 1 0 0 1 1 1 1 WSC domain Glyco_hydro_16 PF00722.21 KPA39936.1 - 3.1e-05 23.5 0.7 4.9e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 E_raikovi_mat PF06360.11 KPA39936.1 - 3.3 8.2 11.1 7.5 7.1 0.3 3.6 4 0 0 4 4 4 0 Euplotes raikovi mating pheromone Pex2_Pex12 PF04757.14 KPA39937.1 - 5.1e-52 176.7 3.2 6.6e-52 176.3 3.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KPA39937.1 - 0.0012 18.9 5.5 0.0022 18.1 5.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KPA39937.1 - 0.0029 17.4 3.6 0.0058 16.5 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPA39937.1 - 0.0043 16.9 2.4 0.008 16.0 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA39937.1 - 0.017 15.4 5.4 0.03 14.7 5.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KPA39937.1 - 0.15 12.0 6.1 0.26 11.2 6.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA39937.1 - 1.2 9.3 5.8 2.5 8.2 5.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger 4HBT PF03061.22 KPA39938.1 - 1.1e-12 48.1 0.0 1.6e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KPA39938.1 - 1.7e-05 25.2 0.0 3.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily F-box PF00646.33 KPA39939.1 - 6.6e-11 41.8 0.5 1.1e-09 37.9 0.0 3.0 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.7 KPA39939.1 - 4.8e-10 39.2 1.1 1.5e-09 37.6 0.2 2.3 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 KPA39939.1 - 0.011 15.6 0.1 0.03 14.2 0.0 1.7 2 0 0 2 2 2 0 F-box FNIP_N PF14636.6 KPA39940.1 - 4e-40 138.3 0.1 4e-40 138.3 0.1 4.7 3 2 0 3 3 3 1 Folliculin-interacting protein N-terminus DEAD PF00270.29 KPA39941.1 - 6.5e-48 162.8 0.0 3e-47 160.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA39941.1 - 3e-24 85.5 0.0 4.7e-23 81.7 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KPA39941.1 - 2.3e-23 82.2 5.2 5.9e-23 80.9 5.2 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain DnaJ PF00226.31 KPA39942.1 - 3e-13 49.7 5.0 6e-13 48.7 0.4 2.8 3 0 0 3 3 3 1 DnaJ domain DnaJ_C PF01556.18 KPA39943.1 - 4.3e-39 134.0 0.0 6.2e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KPA39943.1 - 3.3e-24 84.8 2.9 6.1e-24 83.9 2.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KPA39943.1 - 2.7e-10 40.4 20.3 5.4e-10 39.5 20.3 1.5 1 0 0 1 1 1 1 DnaJ central domain YDG PF18657.1 KPA39943.1 - 0.036 14.3 0.2 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 YDG domain Anti-TRAP PF15777.5 KPA39943.1 - 3.7 7.6 20.1 0.39 10.7 5.1 2.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein SAP30_Sin3_bdg PF13867.6 KPA39944.1 - 3.2e-09 37.0 0.3 3.1e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF2201_N PF13203.6 KPA39944.1 - 0.038 13.6 0.3 0.051 13.2 0.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DHO_dh PF01180.21 KPA39945.1 - 5.1e-20 71.9 0.0 6.1e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 KPA39945.1 - 0.00014 21.4 0.3 0.00016 21.2 0.3 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase Aa_trans PF01490.18 KPA39946.1 - 2.2e-41 141.9 27.1 2.6e-41 141.7 27.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KPA39946.1 - 1e-05 24.7 13.9 1e-05 24.7 13.9 2.2 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Spore_permease PF03845.13 KPA39946.1 - 0.001 18.0 15.9 0.001 18.0 15.9 2.7 2 1 0 2 2 2 1 Spore germination protein TraW_N PF12477.8 KPA39947.1 - 0.094 12.7 0.3 12 6.0 0.0 2.3 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal DUF3109 PF11307.8 KPA39947.1 - 0.14 11.9 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) SKI PF01202.22 KPA39948.1 - 2.4e-10 40.8 0.0 3e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KPA39948.1 - 9e-07 29.5 0.0 1.7e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KPA39948.1 - 7.3e-06 26.2 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KPA39948.1 - 2.8e-05 24.0 0.0 4.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 KPA39948.1 - 0.00072 20.0 0.0 0.0014 19.1 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KPA39948.1 - 0.0021 18.5 0.1 0.0085 16.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain CPT PF07931.12 KPA39948.1 - 0.0035 17.2 0.3 0.018 14.9 0.3 1.9 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 KPA39948.1 - 0.0037 17.7 0.0 0.005 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA39948.1 - 0.0099 16.1 0.0 0.064 13.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KPA39948.1 - 0.017 14.4 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 KPA39948.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.4 1 1 0 1 1 1 0 Adenylylsulphate kinase Rad17 PF03215.15 KPA39948.1 - 0.024 14.6 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain dNK PF01712.19 KPA39948.1 - 0.029 14.2 0.0 0.074 12.9 0.0 1.7 2 0 0 2 2 2 0 Deoxynucleoside kinase RNA_helicase PF00910.22 KPA39948.1 - 0.067 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 KPA39948.1 - 0.083 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CoaE PF01121.20 KPA39948.1 - 0.15 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase CobU PF02283.16 KPA39948.1 - 0.18 11.4 0.0 0.42 10.2 0.0 1.6 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ATPase_2 PF01637.18 KPA39948.1 - 0.2 11.5 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Glyco_hydro_18 PF00704.28 KPA39949.1 - 5.2e-61 207.1 0.2 7.9e-61 206.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KPA39949.1 - 1.2e-09 38.5 7.5 1.2e-09 38.5 7.5 4.7 5 0 0 5 5 5 2 Chitin recognition protein LysM PF01476.20 KPA39950.1 - 1.4e-06 28.3 0.1 0.04 14.0 0.0 3.0 2 1 0 2 2 2 2 LysM domain LysM PF01476.20 KPA39951.1 - 3.1e-13 49.5 1.9 1.2 9.3 0.0 7.0 7 0 0 7 7 7 5 LysM domain CarbpepA_inh PF02977.15 KPA39951.1 - 0.058 13.2 11.8 4.6 7.1 0.1 5.4 5 0 0 5 5 5 0 Carboxypeptidase A inhibitor UPF0203 PF05254.12 KPA39951.1 - 0.12 12.6 25.4 15 5.9 0.1 7.2 7 0 0 7 7 7 0 Uncharacterised protein family (UPF0203) CBP_BcsR PF10945.8 KPA39952.1 - 0.19 11.2 0.7 0.4 10.2 0.7 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR RST PF12174.8 KPA39953.1 - 0.18 11.7 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain MIP PF00230.20 KPA39954.1 - 2.9e-41 141.7 8.4 3.9e-41 141.2 8.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2104 PF09877.9 KPA39954.1 - 0.014 15.7 0.8 0.03 14.6 0.2 1.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2104) DUF1761 PF08570.10 KPA39954.1 - 0.14 12.4 8.3 0.21 11.9 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) ThrE PF06738.12 KPA39954.1 - 2.6 7.3 6.6 3.7 6.8 5.6 1.7 1 1 0 1 1 1 0 Putative threonine/serine exporter FAD_binding_4 PF01565.23 KPA39955.1 - 1.1e-25 90.0 2.6 2.1e-25 89.1 2.6 1.5 1 0 0 1 1 1 1 FAD binding domain AhpC-TSA_2 PF13911.6 KPA39955.1 - 1.6e-16 60.4 0.0 4.1e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KPA39955.1 - 0.0029 17.5 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family DUF899 PF05988.12 KPA39955.1 - 0.0034 17.0 0.0 0.0086 15.6 0.0 1.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF899) BBE PF08031.12 KPA39955.1 - 0.0038 17.3 0.1 0.0081 16.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans PF04082.18 KPA39956.1 - 7.8e-11 41.5 0.0 2.2e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 KPA39958.1 - 1.7e-30 106.5 0.0 3e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPA39958.1 - 7.1e-07 28.5 0.0 5.4e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.16 KPA39958.1 - 0.0029 17.5 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Say1_Mug180 PF10340.9 KPA39958.1 - 0.004 16.1 0.0 0.0086 15.0 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase AXE1 PF05448.12 KPA39958.1 - 0.0046 15.7 0.0 0.0084 14.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KPA39958.1 - 0.055 12.9 0.1 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Zn_clus PF00172.18 KPA39959.1 - 6.2e-09 35.8 11.4 1e-08 35.1 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA39959.1 - 1.5e-08 34.0 0.7 2.9e-08 33.1 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 KPA39960.1 - 2.6e-18 66.4 0.0 3.9e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA39960.1 - 6.5e-15 55.6 0.0 2.4e-13 50.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA39960.1 - 1.3e-10 41.8 0.0 2.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA39960.1 - 1.3e-09 38.7 0.0 7.5e-09 36.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA39960.1 - 1.9e-09 37.5 0.1 4.6e-08 33.0 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA39960.1 - 4.5e-07 29.5 0.0 3.9e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KPA39960.1 - 3.2e-05 23.7 0.0 5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KPA39960.1 - 0.00071 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KPA39960.1 - 0.0017 17.8 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KPA39960.1 - 0.0053 16.2 0.0 0.054 13.0 0.0 2.4 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 KPA39960.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 KPA39960.1 - 0.077 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_PK PF05891.12 KPA39960.1 - 0.11 12.0 0.2 0.2 11.1 0.2 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.7 KPA39960.1 - 0.22 11.4 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_16 PF00722.21 KPA39961.1 - 1.4e-13 50.7 0.3 1.9e-13 50.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Peptidase_M43 PF05572.13 KPA39962.1 - 1.1e-12 48.2 0.0 3.4e-11 43.3 0.0 2.6 2 1 1 3 3 3 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KPA39962.1 - 1.3e-05 25.5 0.0 3.6e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KPA39962.1 - 0.0013 18.5 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KPA39962.1 - 0.0013 18.6 0.2 0.0026 17.6 0.2 1.5 1 1 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 KPA39962.1 - 0.0035 17.9 0.1 0.015 15.8 0.1 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KPA39962.1 - 0.008 15.4 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Met-zincin Peptidase_M66 PF10462.9 KPA39962.1 - 0.18 10.7 0.1 0.3 10.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 adh_short PF00106.25 KPA39963.1 - 3e-33 114.9 0.0 6.4e-33 113.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA39963.1 - 4.3e-20 72.3 0.0 7.1e-20 71.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA39963.1 - 1.9e-11 44.2 0.0 2.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA39963.1 - 0.0017 17.8 0.1 0.0023 17.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KPA39963.1 - 0.0031 17.8 0.0 0.027 14.7 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KPA39963.1 - 0.0051 16.0 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 KPA39963.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KPA39963.1 - 0.16 11.4 0.6 0.25 10.7 0.6 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KPA39964.1 - 6.7e-41 139.9 0.0 1e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA39964.1 - 9.4e-27 94.1 0.0 1.2e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA39964.1 - 2.8e-12 46.9 0.0 4.1e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPA39964.1 - 3.7e-05 23.7 0.0 4.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA39964.1 - 0.0009 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KPA39964.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DUF1776 PF08643.10 KPA39964.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Copper-fist PF00649.18 KPA39966.1 - 0.0048 16.4 2.1 0.0078 15.7 2.1 1.4 1 0 0 1 1 1 1 Copper fist DNA binding domain SapA PF02199.15 KPA39967.1 - 2.6e-08 34.0 3.7 3.4e-08 33.6 3.7 1.2 1 0 0 1 1 1 1 Saposin A-type domain Abhydrolase_1 PF00561.20 KPA39968.1 - 7.1e-23 81.6 0.0 9.3e-23 81.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KPA39968.1 - 8.9e-14 51.5 0.1 4.2e-13 49.3 0.0 2.2 3 0 0 3 3 3 1 TAP-like protein DSBA PF01323.20 KPA39969.1 - 6.9e-33 114.1 0.0 7.7e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KPA39969.1 - 0.00046 20.4 0.0 0.00081 19.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin PLDc_2 PF13091.6 KPA39970.1 - 2.9e-16 59.5 0.0 1.9e-08 34.2 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KPA39970.1 - 0.0015 18.6 0.2 2.2 8.6 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Adap_comp_sub PF00928.21 KPA39971.1 - 2.4e-83 279.5 0.0 3.1e-83 279.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KPA39971.1 - 6.4e-05 22.9 0.3 0.00011 22.1 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KPA39971.1 - 0.088 12.2 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF1936 PF09151.10 KPA39971.1 - 0.19 11.7 0.1 0.49 10.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) CAML PF14963.6 KPA39974.1 - 0.071 13.2 2.7 0.081 13.0 2.7 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand TPR_2 PF07719.17 KPA39975.1 - 1.9e-11 43.1 1.1 2.8e-05 23.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KPA39975.1 - 2.7e-07 30.1 0.1 0.012 15.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPA39975.1 - 8.2e-07 29.6 1.2 0.00031 21.3 2.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPA39975.1 - 1.7e-05 25.0 1.8 0.0026 18.0 0.6 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA39975.1 - 0.0005 20.1 0.0 0.011 15.9 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPA39975.1 - 0.00072 20.2 4.1 0.0055 17.4 0.3 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KPA39975.1 - 0.00091 19.7 0.0 0.01 16.3 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPA39975.1 - 0.013 15.5 0.8 25 5.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KPA39975.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KPA39975.1 - 0.018 15.2 0.3 0.16 12.1 0.2 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPA39975.1 - 0.021 15.4 1.7 0.021 15.4 1.7 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KPA39975.1 - 0.15 11.8 0.0 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 KPA39975.1 - 0.31 11.8 1.4 1.7 9.4 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KPA39975.1 - 2 8.4 5.3 7.2 6.6 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L13 PF00572.18 KPA39976.1 - 6.1e-12 45.9 0.1 7.4e-10 39.1 0.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 DSBA PF01323.20 KPA39976.1 - 0.07 12.9 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain BAG PF02179.16 KPA39977.1 - 2.5e-17 63.1 0.4 4.9e-17 62.1 0.4 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KPA39977.1 - 0.0003 20.5 0.0 0.00085 19.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 KPA39977.1 - 0.028 14.4 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain RSB_motif PF16294.5 KPA39977.1 - 0.039 14.2 1.3 0.11 12.8 1.3 1.8 1 1 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif YqzE PF14038.6 KPA39977.1 - 0.33 11.0 4.9 1.1 9.3 2.2 2.4 2 0 0 2 2 2 0 YqzE-like protein Glutaredoxin PF00462.24 KPA39978.1 - 3.1e-20 72.1 0.4 5.6e-20 71.3 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.6 KPA39978.1 - 0.00027 21.4 0.3 0.00037 20.9 0.2 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 KPA39978.1 - 0.0018 18.6 0.2 0.0024 18.3 0.2 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 KPA39978.1 - 0.0028 17.5 0.1 0.0072 16.1 0.1 1.8 1 1 1 2 2 2 1 DSBA-like thioredoxin domain TraF PF13728.6 KPA39978.1 - 0.0032 17.3 0.0 0.0037 17.1 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin PF00085.20 KPA39978.1 - 0.009 16.0 0.0 0.009 16.0 0.0 1.2 1 1 0 1 1 1 1 Thioredoxin GST_N_3 PF13417.6 KPA39978.1 - 0.01 16.2 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Redoxin PF08534.10 KPA39978.1 - 0.09 12.5 0.1 0.12 12.0 0.1 1.3 1 1 0 1 1 1 0 Redoxin Thioredoxin_3 PF13192.6 KPA39978.1 - 0.09 12.8 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 KPA39978.1 - 0.093 12.9 0.4 0.49 10.5 0.3 1.9 1 1 0 2 2 2 0 Thioredoxin Chalcone_2 PF16035.5 KPA39979.1 - 1.1e-76 257.2 0.0 1.6e-76 256.6 0.0 1.3 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KPA39979.1 - 2e-05 24.8 1.5 0.0012 19.0 0.1 2.6 2 1 1 3 3 3 2 Chalcone isomerase-like UPF0542 PF15086.6 KPA39979.1 - 0.059 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 CbtA PF09490.10 KPA39979.1 - 0.09 12.5 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) LRR_6 PF13516.6 KPA39980.1 - 6.4e-16 57.0 25.8 0.033 14.2 0.1 11.6 12 0 0 12 12 12 6 Leucine Rich repeat F-box-like PF12937.7 KPA39980.1 - 6.7e-13 48.3 1.5 1.5e-12 47.2 0.8 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KPA39980.1 - 1.1e-07 32.0 18.3 1.2 9.7 0.0 7.1 5 2 0 6 6 6 3 Leucine Rich repeats (2 copies) F-box PF00646.33 KPA39980.1 - 6.8e-07 29.0 0.2 3.3e-06 26.8 0.2 2.3 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.11 KPA39980.1 - 0.00042 20.0 0.7 0.38 10.4 0.0 3.3 3 1 1 4 4 4 2 Protein of unknown function (DUF1699) Ammonium_transp PF00909.21 KPA39981.1 - 1.9e-120 402.2 20.6 2.2e-120 402.0 20.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 KPA39981.1 - 0.17 11.9 4.1 1 9.4 0.7 3.0 2 0 0 2 2 2 0 Bacteriophage P21 holin S Pept_tRNA_hydro PF01195.19 KPA39982.1 - 1.2e-28 100.2 0.0 1.4e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase BAR PF03114.18 KPA39983.1 - 2.3e-66 223.9 6.5 2.9e-66 223.5 6.5 1.1 1 0 0 1 1 1 1 BAR domain HAUS-augmin3 PF14932.6 KPA39983.1 - 0.0033 17.1 1.0 0.034 13.7 0.1 2.3 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 PTPS PF01242.19 KPA39983.1 - 0.095 12.7 1.2 0.44 10.5 0.2 2.4 2 1 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase SVIP PF15811.5 KPA39983.1 - 1.6 9.2 5.7 0.24 11.9 0.6 2.2 2 1 0 2 2 2 0 Small VCP/p97-interacting protein DCP1 PF06058.13 KPA39984.1 - 2.1e-33 114.7 0.0 3.9e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.23 KPA39985.1 - 3e-05 23.7 0.0 8.2e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 KPA39985.1 - 0.14 12.0 0.0 0.43 10.4 0.0 1.8 1 1 0 1 1 1 0 RhoGAP domain Zn_clus PF00172.18 KPA39987.1 - 0.0045 17.1 9.6 0.017 15.2 9.6 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 KPA39988.1 - 1.7e-17 64.1 0.0 2.1e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KPA39988.1 - 0.00091 18.4 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 CsiD DUF1996 PF09362.10 KPA39989.1 - 1.7e-63 214.7 2.0 2.7e-63 214.1 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Methyltr_RsmB-F PF01189.17 KPA39990.1 - 3.6e-16 59.4 0.0 3.6e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F TMV_coat PF00721.21 KPA39990.1 - 0.0089 15.9 0.0 0.03 14.2 0.0 1.8 2 0 0 2 2 2 1 Virus coat protein (TMV like) MCM PF00493.23 KPA39991.1 - 4.7e-104 346.4 0.1 1.4e-103 344.9 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KPA39991.1 - 6.5e-38 129.4 0.3 1.2e-37 128.6 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KPA39991.1 - 3.9e-28 97.7 1.3 8.7e-28 96.6 1.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KPA39991.1 - 6.1e-16 58.9 0.6 1.6e-15 57.6 0.6 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KPA39991.1 - 2e-06 27.3 0.0 0.00021 20.8 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KPA39991.1 - 9.1e-06 25.7 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KPA39991.1 - 0.00013 21.9 0.0 0.00074 19.4 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KPA39991.1 - 0.025 15.0 0.2 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KPA39991.1 - 0.051 13.3 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DNA_RNApol_7kD PF03604.13 KPA39991.1 - 0.059 13.1 0.8 3.3 7.4 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit AAA_16 PF13191.6 KPA39991.1 - 0.2 12.0 1.0 1.5 9.1 0.1 2.7 1 1 1 2 2 2 0 AAA ATPase domain Vps54 PF07928.12 KPA39992.1 - 5.2e-52 175.8 2.7 3.9e-51 173.0 0.2 3.1 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 KPA39992.1 - 5.9e-07 29.1 0.9 1.6e-06 27.6 0.9 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Glyco_transf_88 PF16849.5 KPA39992.1 - 0.0092 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 88 DUF5364 PF17322.2 KPA39992.1 - 0.017 15.5 0.7 0.017 15.5 0.7 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5364) Sec8_exocyst PF04048.14 KPA39992.1 - 0.093 12.6 4.5 0.25 11.2 1.0 2.9 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain COG2 PF06148.11 KPA39992.1 - 0.1 12.7 2.7 0.49 10.5 1.5 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1843 PF08898.10 KPA39992.1 - 0.21 12.1 1.3 0.77 10.3 1.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) APG6_N PF17675.1 KPA39992.1 - 1.1 9.8 7.8 0.16 12.5 2.3 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region OmpH PF03938.14 KPA39992.1 - 1.3 9.4 7.3 1.6 9.0 0.5 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Big_9 PF17963.1 KPA39993.1 - 0.01 16.5 0.2 0.026 15.2 0.2 1.6 1 0 0 1 1 1 0 Bacterial Ig domain ANAPC8 PF04049.13 KPA39995.1 - 3.2e-57 192.5 0.8 8e-57 191.2 0.1 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KPA39995.1 - 6.4e-22 76.4 8.4 9e-05 22.1 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KPA39995.1 - 9.7e-22 75.3 10.9 6.8e-05 22.8 0.0 7.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KPA39995.1 - 4e-14 51.5 18.9 0.048 13.8 0.0 9.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KPA39995.1 - 1.4e-09 38.1 18.4 0.18 12.1 0.1 7.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KPA39995.1 - 2e-08 33.8 0.6 1.1e-06 28.2 0.1 3.3 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.6 KPA39995.1 - 3.3e-08 33.7 17.3 0.0056 17.4 0.1 8.9 8 3 2 10 10 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPA39995.1 - 1e-07 32.5 12.3 2.4e-05 24.9 0.1 6.2 7 1 0 7 7 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPA39995.1 - 5.7e-07 29.1 8.5 0.032 14.3 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KPA39995.1 - 5.4e-06 26.4 0.4 6.4 7.4 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA39995.1 - 6.9e-06 26.2 9.8 0.059 13.6 0.9 5.5 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KPA39995.1 - 7.7e-05 23.1 9.2 5.6 7.6 0.0 7.0 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KPA39995.1 - 0.00029 20.6 1.9 1.1 9.3 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 KPA39995.1 - 0.0007 19.7 1.5 0.07 13.2 0.1 3.3 2 1 0 3 3 2 1 Domain of Unknown Function (DUF3856) TPR_9 PF13371.6 KPA39995.1 - 0.001 19.2 9.1 2.2 8.5 0.3 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KPA39995.1 - 0.0071 15.8 1.2 0.027 13.8 0.3 2.2 2 0 0 2 2 2 1 MalT-like TPR region TPR_6 PF13174.6 KPA39995.1 - 0.064 13.9 21.0 4 8.3 0.1 8.2 10 0 0 10 10 8 0 Tetratricopeptide repeat Say1_Mug180 PF10340.9 KPA39995.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Sel1 PF08238.12 KPA39995.1 - 0.81 10.5 9.2 18 6.2 0.1 5.5 6 0 0 6 6 6 0 Sel1 repeat HTH_32 PF13565.6 KPA39996.1 - 0.045 14.4 0.4 0.45 11.2 0.2 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Npun_R1517 PF18068.1 KPA39996.1 - 0.074 13.4 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Npun R1517 polyprenyl_synt PF00348.17 KPA39997.1 - 4.8e-92 307.6 0.0 5.9e-92 307.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase YkyB PF14177.6 KPA39997.1 - 0.046 14.0 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 YkyB-like protein PH PF00169.29 KPA39998.1 - 0.00013 22.4 0.1 0.00033 21.1 0.1 1.7 1 0 0 1 1 1 1 PH domain RmlD_sub_bind PF04321.17 KPA39999.1 - 2.1e-51 174.8 0.0 2.5e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KPA39999.1 - 6.3e-19 68.4 0.0 8.1e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPA39999.1 - 1.5e-08 34.2 0.2 4.2e-06 26.1 0.0 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KPA39999.1 - 1.4e-07 30.9 0.0 4e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KPA39999.1 - 1.6e-07 31.1 0.0 3.7e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Utp13 PF08625.11 KPA40001.1 - 1.8e-50 170.6 0.1 3.1e-50 169.8 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 KPA40001.1 - 1.5e-46 155.4 28.4 4.4e-05 24.2 0.0 11.8 11 1 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA40001.1 - 9.4e-14 51.5 9.5 0.092 13.1 0.1 9.0 6 3 2 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA40001.1 - 3.1e-07 29.4 7.3 0.31 9.6 0.0 5.8 2 2 2 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KPA40001.1 - 0.11 11.2 6.6 6.9 5.3 0.2 4.7 5 1 0 5 5 5 0 Nup133 N terminal like UCH PF00443.29 KPA40002.1 - 7.7e-25 87.9 0.0 1.2e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KPA40002.1 - 7e-12 45.5 1.6 7.2e-12 45.5 0.2 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KPA40002.1 - 0.012 15.2 0.1 0.13 11.9 0.1 2.2 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase IF4E PF01652.18 KPA40003.1 - 1.7e-53 180.7 0.0 2.2e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NmrA PF05368.13 KPA40004.1 - 1.3e-16 60.9 0.0 1.7e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA40004.1 - 2.2e-10 40.7 0.0 3.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA40004.1 - 7.4e-06 25.6 0.1 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KPA40004.1 - 1.3e-05 25.4 0.2 0.00011 22.4 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain KR PF08659.10 KPA40004.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_7 PF13241.6 KPA40004.1 - 0.015 15.7 0.1 0.076 13.5 0.0 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 KPA40004.1 - 0.027 14.6 0.1 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase p450 PF00067.22 KPA40005.1 - 2.1e-34 119.1 0.0 1.3e-33 116.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 KPA40006.1 - 4e-47 160.8 0.0 5e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPA40006.1 - 2.9e-11 42.9 0.1 1.2e-10 40.9 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KPA40006.1 - 0.037 13.5 0.0 5.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_125 PF06824.11 KPA40007.1 - 9.5e-149 495.8 0.2 1.1e-148 495.6 0.2 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DUF4199 PF13858.6 KPA40009.1 - 0.054 13.9 2.1 0.56 10.6 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) ECSCR PF15820.5 KPA40009.1 - 1.1 9.1 5.1 2.2 8.2 0.3 2.4 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Peptidase_S37 PF05576.11 KPA40010.1 - 0.041 12.6 1.1 0.049 12.3 0.1 1.5 2 0 0 2 2 2 0 PS-10 peptidase S37 DUF4213 PF13938.6 KPA40010.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative heavy-metal chelation H_lectin PF09458.10 KPA40011.1 - 1.7e-20 72.9 4.4 2.5e-11 43.6 0.1 4.3 4 0 0 4 4 4 3 H-type lectin domain GMC_oxred_C PF05199.13 KPA40012.1 - 9.7e-19 68.3 0.0 1.9e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KPA40012.1 - 2.4e-05 23.9 0.0 0.00065 19.2 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KPA40012.1 - 0.00019 20.8 0.1 0.00055 19.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA40012.1 - 0.022 15.0 0.0 0.058 13.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KPA40012.1 - 0.052 13.8 0.3 7.6 6.8 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.24 KPA40012.1 - 0.084 11.9 0.1 0.27 10.3 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain DUF805 PF05656.14 KPA40013.1 - 0.015 15.7 0.5 0.029 14.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Aminotran_3 PF00202.21 KPA40014.1 - 3.5e-65 220.2 0.1 1e-60 205.5 0.0 3.0 1 1 1 2 2 2 2 Aminotransferase class-III Peripla_BP_4 PF13407.6 KPA40014.1 - 0.045 13.3 0.3 0.14 11.7 0.3 1.9 2 1 0 2 2 2 0 Periplasmic binding protein domain Dabb PF07876.12 KPA40015.1 - 4.1e-08 33.7 0.0 4.9e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain zf_PR_Knuckle PF18445.1 KPA40015.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 PR zinc knuckle motif p450 PF00067.22 KPA40016.1 - 3.9e-28 98.4 0.1 4.5e-27 94.9 0.0 2.3 3 0 0 3 3 3 2 Cytochrome P450 ketoacyl-synt PF00109.26 KPA40017.1 - 3.3e-70 236.6 0.2 7.6e-70 235.4 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KPA40017.1 - 1e-62 211.2 0.1 2.3e-62 210.1 0.1 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KPA40017.1 - 1.3e-50 172.3 0.2 3.1e-50 171.1 0.2 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KPA40017.1 - 7.8e-46 157.0 0.3 1.4e-45 156.2 0.3 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KPA40017.1 - 8.7e-39 132.2 2.6 4.1e-38 130.0 0.8 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KPA40017.1 - 8e-21 75.5 0.0 6.4e-20 72.6 0.0 2.5 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KPA40017.1 - 3.8e-19 69.0 0.0 1.8e-18 66.7 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KPA40017.1 - 6.8e-19 68.4 0.0 2e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KPA40017.1 - 6.2e-17 62.1 0.0 2.7e-16 60.0 0.0 2.1 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KPA40017.1 - 5.1e-13 48.9 0.0 1.4e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KPA40017.1 - 4.1e-11 43.0 0.0 1.2e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40017.1 - 4.8e-11 43.2 0.0 2.5e-10 40.9 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KPA40017.1 - 8.1e-09 35.7 0.1 3.5e-08 33.7 0.1 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KPA40017.1 - 2.5e-08 33.8 0.0 6.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 KPA40017.1 - 3.5e-08 34.0 0.0 1.2e-07 32.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA40017.1 - 5.3e-08 32.8 0.0 1.5e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KPA40017.1 - 1.5e-05 24.9 1.2 3.6e-05 23.6 1.2 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ubie_methyltran PF01209.18 KPA40017.1 - 0.00015 21.2 0.0 0.00033 20.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KPA40017.1 - 0.013 15.2 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Polysacc_synt_2 PF02719.15 KPA40017.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_16 PF10294.9 KPA40017.1 - 0.077 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Lysine methyltransferase Cas1_AcylT PF07779.12 KPA40019.1 - 1.1e-117 393.9 15.2 2.9e-117 392.5 15.2 1.6 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Phage_HK97_TLTM PF06120.11 KPA40019.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein PC-Esterase PF13839.6 KPA40019.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p adh_short PF00106.25 KPA40020.1 - 3.6e-09 36.4 0.0 3.5e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA40020.1 - 0.00095 18.8 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA40020.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Acetyltransf_2 PF00797.17 KPA40021.1 - 6e-46 157.2 0.1 2.3e-44 152.0 0.1 2.1 1 1 0 1 1 1 1 N-acetyltransferase Peptidase_C71 PF12386.8 KPA40021.1 - 0.011 15.4 0.2 0.024 14.3 0.2 1.5 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei Fungal_trans PF04082.18 KPA40022.1 - 2.6e-11 43.1 0.2 4.2e-11 42.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA40022.1 - 5.9e-07 29.5 11.8 1.2e-06 28.5 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Imp-YgjV PF10688.9 KPA40022.1 - 0.072 12.9 0.5 0.13 12.1 0.5 1.4 1 0 0 1 1 1 0 Bacterial inner membrane protein FA_desaturase PF00487.24 KPA40023.1 - 7.6e-27 94.8 24.4 1.5e-26 93.8 24.4 1.5 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KPA40023.1 - 0.00091 19.4 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Glyco_trans_2_3 PF13632.6 KPA40024.1 - 2.9e-18 66.5 0.2 2.9e-18 66.5 0.2 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KPA40024.1 - 1.7e-16 60.9 0.0 2.8e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPA40024.1 - 4e-13 49.5 0.0 7.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 KPA40024.1 - 7.1e-13 48.0 1.6 4.4e-09 35.4 0.1 3.4 2 1 2 4 4 4 2 Cellulose synthase Glyco_transf_21 PF13506.6 KPA40024.1 - 2.4e-12 46.7 0.0 4.5e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KPA40024.1 - 0.0017 17.1 0.1 0.12 11.0 0.1 2.3 2 0 0 2 2 2 2 Chitin synthase PIG-P PF08510.12 KPA40024.1 - 8.4 6.3 6.8 3.8 7.4 0.2 3.3 4 0 0 4 4 4 0 PIG-P Glyco_hydro_12 PF01670.16 KPA40025.1 - 8.2e-20 71.7 4.9 1.1e-15 58.3 0.8 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 12 PetL PF05115.14 KPA40025.1 - 0.24 11.4 1.6 0.44 10.6 1.6 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Acetyltransf_1 PF00583.25 KPA40026.1 - 2.5e-08 34.1 0.0 4.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PanZ PF12568.8 KPA40026.1 - 0.00056 19.6 0.0 0.00097 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Pho86 PF11124.8 KPA40026.1 - 0.00066 19.2 0.1 0.00089 18.8 0.1 1.3 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Acetyltransf_3 PF13302.7 KPA40026.1 - 0.0031 18.2 0.0 0.0049 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA40026.1 - 0.02 15.3 0.1 0.05 14.0 0.0 1.7 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 KPA40027.1 - 1.3e-46 159.4 16.1 1.7e-46 159.0 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA40027.1 - 2.4e-20 72.8 17.2 2.4e-20 72.8 17.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Nup35_RRM_2 PF14605.6 KPA40027.1 - 0.13 12.3 0.1 0.64 10.1 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Transferase PF02458.15 KPA40029.1 - 1e-21 77.2 0.0 5.2e-21 74.8 0.0 1.8 2 0 0 2 2 2 1 Transferase family CTP_synth_N PF06418.14 KPA40030.1 - 4.6e-121 403.2 0.1 6.1e-121 402.8 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KPA40030.1 - 1.2e-49 168.7 0.0 1.8e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KPA40030.1 - 3.9e-05 23.5 0.0 0.00021 21.1 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KPA40030.1 - 0.004 17.2 0.0 0.0062 16.6 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Ligase_CoA PF00549.19 KPA40031.1 - 1.9e-18 66.8 0.8 4.9e-18 65.4 0.8 1.7 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KPA40031.1 - 2.7e-14 53.6 0.4 2.7e-14 53.6 0.4 2.5 2 1 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 KPA40031.1 - 4.8e-09 36.1 0.1 8.3e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain bZIP_1 PF00170.21 KPA40032.1 - 6.4e-05 23.0 10.7 0.00011 22.3 10.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPA40032.1 - 0.00042 20.4 11.0 0.00078 19.5 10.8 1.6 1 1 0 1 1 1 1 Basic region leucine zipper TMF_DNA_bd PF12329.8 KPA40032.1 - 1.8 8.6 9.4 4 7.5 4.6 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Glycos_transf_1 PF00534.20 KPA40033.1 - 2.1e-08 33.9 0.0 3.1e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KPA40033.1 - 1.1e-07 32.3 0.0 1.5e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycogen_syn PF05693.13 KPA40033.1 - 0.0045 15.6 0.0 0.0049 15.5 0.0 1.1 1 0 0 1 1 1 1 Glycogen synthase Alpha-amylase PF00128.24 KPA40034.1 - 2.4e-66 224.6 2.9 3e-66 224.3 2.9 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KPA40034.1 - 0.032 13.3 0.1 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Ligase_CoA PF00549.19 KPA40036.1 - 6.3e-19 68.3 1.2 1.2e-18 67.4 1.2 1.4 1 0 0 1 1 1 1 CoA-ligase DUF2306 PF10067.9 KPA40037.1 - 3.7e-16 59.7 6.6 3.7e-16 59.7 6.6 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) GBV-C_env PF12786.7 KPA40037.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope DUF420 PF04238.12 KPA40037.1 - 0.037 14.3 0.5 0.037 14.3 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF420) Caps_synth PF05704.12 KPA40038.1 - 2.1e-11 43.7 0.9 3.4e-11 43.1 0.9 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KPA40038.1 - 2.4e-07 31.3 0.0 6.1e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif FAM110_C PF14160.6 KPA40039.1 - 0.072 14.2 1.8 0.1 13.7 0.1 2.0 2 0 0 2 2 2 0 Centrosome-associated C terminus DUF1869 PF08956.10 KPA40039.1 - 0.098 12.6 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) DUF4407 PF14362.6 KPA40039.1 - 0.12 11.7 8.4 0.23 10.8 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YscO PF07321.12 KPA40039.1 - 0.16 11.9 19.0 1.3 8.9 1.0 2.4 2 0 0 2 2 2 0 Type III secretion protein YscO PRKG1_interact PF15898.5 KPA40039.1 - 0.42 11.6 17.8 0.97 10.4 8.2 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TLE_N PF03920.15 KPA40039.1 - 0.48 10.5 5.6 0.91 9.6 0.2 2.7 2 1 1 3 3 3 0 Groucho/TLE N-terminal Q-rich domain Holin_BhlA PF10960.8 KPA40039.1 - 0.52 10.3 5.5 0.11 12.5 1.9 1.7 2 0 0 2 2 1 0 BhlA holin family AAA_13 PF13166.6 KPA40039.1 - 0.68 8.5 11.4 0.98 8.0 11.4 1.1 1 0 0 1 1 1 0 AAA domain TolA_bind_tri PF16331.5 KPA40039.1 - 0.8 9.8 12.9 1.9 8.6 0.3 3.2 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF668 PF05003.12 KPA40039.1 - 1.1 9.8 4.1 2.4 8.7 2.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF668) CortBP2 PF09727.9 KPA40039.1 - 1.5 8.7 25.5 1.3 8.9 1.5 3.1 1 1 2 3 3 3 0 Cortactin-binding protein-2 TPR_MLP1_2 PF07926.12 KPA40039.1 - 2 8.5 25.4 0.52 10.4 4.2 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KPA40039.1 - 2.8 6.8 22.7 1.4 7.7 3.3 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein FUSC PF04632.12 KPA40039.1 - 3.7 6.0 5.6 6.6 5.1 5.6 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 KPA40039.1 - 3.9 7.9 19.8 0.39 11.2 11.3 2.1 1 1 1 2 2 2 0 Fez1 DUF1192 PF06698.11 KPA40039.1 - 5.1 7.2 8.5 1 9.5 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) YabA PF06156.13 KPA40039.1 - 5.3 7.7 16.4 0.095 13.4 1.9 2.9 1 1 1 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 KPA40039.1 - 8.1 7.0 26.4 4 8.0 5.6 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KPA40039.1 - 9.2 6.8 10.7 9 6.8 0.8 4.2 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) MFS_1 PF07690.16 KPA40040.1 - 1.2e-28 100.1 24.7 2.5e-27 95.8 15.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Reprolysin_5 PF13688.6 KPA40041.1 - 8.7e-57 192.4 0.8 8.7e-57 192.4 0.8 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KPA40041.1 - 1.2e-48 165.5 0.1 2.1e-48 164.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KPA40041.1 - 1.3e-46 158.9 0.1 2.3e-46 158.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KPA40041.1 - 6e-16 59.0 30.5 6e-16 59.0 30.5 2.8 2 0 0 2 2 2 1 Disintegrin Reprolysin_3 PF13582.6 KPA40041.1 - 6.4e-15 55.8 0.0 2.1e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KPA40041.1 - 3.2e-06 27.2 4.9 5e-05 23.3 1.9 2.8 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KPA40041.1 - 0.014 15.7 0.1 0.032 14.5 0.1 1.6 1 0 0 1 1 1 0 Reprolysin family propeptide Peptidase_M66 PF10462.9 KPA40041.1 - 0.093 11.7 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF1505 PF07403.11 KPA40042.1 - 0.031 14.4 0.1 0.037 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) BRO1 PF03097.18 KPA40043.1 - 1.4e-120 402.7 0.0 2.2e-120 402.1 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KPA40043.1 - 4.3e-84 282.3 7.0 4.3e-84 282.3 7.0 2.0 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV Pex14_N PF04695.13 KPA40043.1 - 3.7 8.2 13.5 8.4 7.0 13.5 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Epimerase PF01370.21 KPA40044.1 - 5.5e-24 84.9 0.0 2.4e-23 82.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA40044.1 - 8.5e-17 61.5 0.1 7.5e-13 48.6 0.0 2.9 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KPA40044.1 - 4.2e-11 42.5 0.0 5.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KPA40044.1 - 3.6e-10 39.5 0.3 1e-06 28.1 0.0 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KPA40044.1 - 7.2e-08 31.9 0.0 6.3e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KPA40044.1 - 8.6e-06 24.9 0.0 2.9e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family N6_Mtase PF02384.16 KPA40044.1 - 0.0043 16.4 0.0 0.038 13.3 0.0 2.1 2 0 0 2 2 2 1 N-6 DNA Methylase Band_7 PF01145.25 KPA40046.1 - 1.4e-14 54.5 0.1 1.4e-14 54.5 0.1 3.4 2 1 0 2 2 2 1 SPFH domain / Band 7 family EphA2_TM PF14575.6 KPA40047.1 - 0.046 14.6 0.0 0.063 14.2 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RVT_2 PF07727.14 KPA40048.1 - 0.012 15.3 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Inositol_P PF00459.25 KPA40049.1 - 1.8e-34 119.5 0.9 5.6e-34 117.9 0.9 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family TetR_C_14 PF17754.1 KPA40049.1 - 0.014 15.4 1.9 0.35 10.8 0.4 2.4 2 0 0 2 2 2 0 MftR C-terminal domain Rep-A_N PF04057.12 KPA40050.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain F-box-like PF12937.7 KPA40051.1 - 1.6e-06 27.9 0.5 4.6e-06 26.4 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA40051.1 - 1.1e-05 25.2 0.0 3.3e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 KPA40052.1 - 2.1e-15 56.5 19.9 5.1e-15 55.3 19.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KPA40052.1 - 0.14 11.6 8.8 0.08 12.4 3.6 2.7 2 1 0 2 2 2 0 Nodulin-like DUF4516 PF14990.6 KPA40052.1 - 1 9.1 2.8 0.7 9.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) 7tm_7 PF08395.12 KPA40052.1 - 3.7 6.6 7.4 0.82 8.8 0.2 2.9 4 0 0 4 4 4 0 7tm Chemosensory receptor COesterase PF00135.28 KPA40053.1 - 6.4e-84 282.7 0.0 8.4e-84 282.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA40053.1 - 0.0032 17.3 0.1 0.023 14.6 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KPA40054.1 - 1.8e-34 119.3 34.0 2.2e-34 118.9 34.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPA40054.1 - 2.6e-05 23.7 6.9 2.6e-05 23.7 6.9 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Amidohydro_3 PF07969.11 KPA40055.1 - 1e-71 242.9 0.8 1.2e-71 242.7 0.8 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KPA40055.1 - 1.1e-15 57.8 0.2 3.8e-12 46.2 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Zn_clus PF00172.18 KPA40058.1 - 4.3e-09 36.3 10.4 4.3e-09 36.3 10.4 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA40058.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.7 KPA40059.1 - 2.6e-17 64.2 0.5 3.2e-17 63.9 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA40059.1 - 2e-16 60.4 0.2 1.2e-15 57.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA40059.1 - 3.2e-08 33.1 0.0 4.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KPA40059.1 - 1.9e-06 26.8 0.0 3.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Ndr family FA_desaturase PF00487.24 KPA40060.1 - 1.5e-31 110.1 18.2 2.1e-31 109.7 18.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KPA40060.1 - 1.4e-08 34.8 0.0 3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ank_4 PF13637.6 KPA40061.1 - 2.5e-06 27.9 0.1 0.0084 16.7 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA40061.1 - 3e-06 27.7 0.0 1.8e-05 25.3 0.0 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA40061.1 - 0.00025 21.2 0.1 1.2 10.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat F-box PF00646.33 KPA40061.1 - 0.0076 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain Ank_4 PF13637.6 KPA40062.1 - 9.1e-05 22.9 0.1 0.019 15.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA40062.1 - 0.0081 16.5 0.0 0.025 14.9 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KPA40062.1 - 0.009 16.4 0.0 0.26 11.8 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KPA40062.1 - 0.0092 16.6 0.0 0.026 15.1 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA40062.1 - 0.15 12.7 0.0 1.6 9.6 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeat PRANC PF09372.10 KPA40062.1 - 0.15 12.4 0.3 6.2 7.2 0.0 2.2 1 1 1 2 2 2 0 PRANC domain F-box-like_2 PF13013.6 KPA40063.1 - 0.019 14.9 0.2 14 5.7 0.0 3.5 3 0 0 3 3 3 0 F-box-like domain DMA PF03474.14 KPA40063.1 - 0.15 11.7 1.8 5.3 6.7 0.3 3.5 4 0 0 4 4 4 0 DMRTA motif FOXP-CC PF16159.5 KPA40064.1 - 0.6 10.8 3.5 0.38 11.4 0.8 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF1682 PF07946.14 KPA40064.1 - 3.3 6.8 6.3 4.6 6.3 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AAR2 PF05282.11 KPA40065.1 - 1.4e-51 176.0 0.0 2.1e-51 175.4 0.0 1.3 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S9 PF00380.19 KPA40066.1 - 6.2e-34 117.1 0.1 7.1e-34 116.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L32e PF01655.18 KPA40067.1 - 5.2e-49 165.2 0.9 5.2e-49 165.2 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L32 PDH PF02153.17 KPA40069.1 - 8.5e-17 61.0 0.0 1.3e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KPA40069.1 - 0.0038 17.4 0.0 0.0073 16.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KPA40069.1 - 0.0079 16.8 0.5 0.063 13.9 0.1 2.5 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KPA40069.1 - 0.012 15.7 0.0 0.034 14.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KPA40069.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RCC1 PF00415.18 KPA40070.1 - 5.9e-31 106.9 12.6 2.3e-11 44.1 0.1 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KPA40070.1 - 1.4e-15 56.6 23.1 5.2e-06 26.1 2.2 5.9 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.13 KPA40071.1 - 2.5e-46 158.2 0.4 3.1e-46 157.9 0.4 1.1 1 0 0 1 1 1 1 Rad9 Glyco_hydro_18 PF00704.28 KPA40072.1 - 5.7e-63 213.5 0.0 6.5e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UDPG_MGDP_dh PF00984.19 KPA40073.1 - 1.1e-18 67.2 0.0 2.2e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 KPA40073.1 - 1.4e-17 63.9 0.2 1.5e-15 57.2 0.2 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 KPA40073.1 - 0.00017 21.8 0.0 0.00028 21.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KPA40073.1 - 0.024 14.9 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_25 PF13649.6 KPA40073.1 - 0.029 15.1 0.0 0.13 13.0 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Chitin_synth_2 PF03142.15 KPA40074.1 - 9.1e-36 123.6 7.2 4.1e-28 98.3 3.1 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KPA40074.1 - 9.5e-08 32.2 11.0 1.6e-07 31.4 5.3 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KPA40074.1 - 2.6e-06 27.3 0.0 0.0088 15.9 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 RAMP4 PF06624.12 KPA40074.1 - 2.8 8.1 4.1 8.3 6.6 4.1 1.8 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 Polysacc_deac_1 PF01522.21 KPA40075.1 - 8.9e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KPA40075.1 - 1.7e-15 57.2 77.6 1e-05 25.9 18.7 3.5 3 0 0 3 3 3 3 Chitin recognition protein Kv2channel PF03521.14 KPA40075.1 - 0.055 12.8 1.9 0.11 11.8 1.9 1.4 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel DUF2334 PF10096.9 KPA40075.1 - 0.088 12.4 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) FAR1 PF03101.15 KPA40076.1 - 1e-05 26.1 0.2 1.6e-05 25.5 0.2 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain Sugarporin_N PF11471.8 KPA40076.1 - 0.00025 20.9 1.9 0.0071 16.3 0.2 2.8 2 1 1 3 3 3 1 Maltoporin periplasmic N-terminal extension AFT PF08731.11 KPA40076.1 - 0.0022 18.4 0.0 0.0032 17.9 0.0 1.4 1 0 0 1 1 1 1 Transcription factor AFT XhlA PF10779.9 KPA40076.1 - 0.0031 17.7 0.2 0.0088 16.2 0.1 1.9 2 1 0 2 2 2 1 Haemolysin XhlA Snapin_Pallidin PF14712.6 KPA40076.1 - 0.0039 17.6 0.1 0.0086 16.5 0.1 1.6 1 0 0 1 1 1 1 Snapin/Pallidin Hemagglutinin PF00509.18 KPA40076.1 - 0.037 12.4 0.0 0.047 12.1 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin HSBP1 PF06825.12 KPA40076.1 - 0.052 13.4 4.9 0.13 12.2 0.8 2.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 CLZ PF16526.5 KPA40076.1 - 0.094 13.1 0.8 0.37 11.2 0.6 1.9 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Matrilin_ccoil PF10393.9 KPA40076.1 - 0.12 12.3 1.7 1.1 9.2 0.9 2.6 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin YPEB PF14620.6 KPA40076.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 YpeB sporulation CCDC53 PF10152.9 KPA40076.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex YvrJ PF12841.7 KPA40076.1 - 0.35 10.5 1.5 1 9.0 0.7 2.1 2 0 0 2 2 2 0 YvrJ protein family Ribosomal_L34e PF01199.18 KPA40078.1 - 7.6e-43 144.8 3.0 1.1e-42 144.3 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 KPA40078.1 - 0.29 11.1 4.2 1.7 8.7 0.3 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Zn_ribbon_recom PF13408.6 KPA40078.1 - 3.2 8.3 8.0 0.56 10.8 3.0 2.2 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF498 PF04430.14 KPA40079.1 - 8.4e-27 93.4 0.0 1.8e-26 92.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) Abhydrolase_6 PF12697.7 KPA40080.1 - 4.7e-20 73.1 2.0 1e-19 72.1 2.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA40080.1 - 2.3e-18 66.8 0.0 8e-18 65.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA40080.1 - 4.7e-17 62.0 0.0 6.7e-16 58.3 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 KPA40080.1 - 3.2e-09 36.7 0.0 5.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KPA40080.1 - 6.8e-05 23.0 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KPA40080.1 - 0.00013 21.6 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Thioesterase PF00975.20 KPA40080.1 - 0.00021 21.5 0.0 0.00049 20.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KPA40080.1 - 0.00062 19.5 0.0 0.0046 16.7 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KPA40080.1 - 0.0084 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KPA40080.1 - 0.01 15.7 0.0 7.4 6.3 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 KPA40080.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 KPA40080.1 - 0.017 14.8 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 KPA40080.1 - 0.031 14.1 0.0 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF900 PF05990.12 KPA40080.1 - 0.035 13.6 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 KPA40080.1 - 0.045 13.6 0.1 0.13 12.1 0.1 1.7 1 1 1 2 2 2 0 Lipase (class 3) Ser_hydrolase PF06821.13 KPA40080.1 - 0.053 13.4 0.1 0.99 9.2 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase VirJ PF06057.11 KPA40080.1 - 0.095 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Esterase_phd PF10503.9 KPA40080.1 - 0.1 12.1 0.1 3.6 7.0 0.0 2.5 2 1 0 2 2 2 0 Esterase PHB depolymerase LCAT PF02450.15 KPA40080.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3089 PF11288.8 KPA40080.1 - 0.18 11.3 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF676 PF05057.14 KPA40080.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Alk_phosphatase PF00245.20 KPA40081.1 - 3.2e-105 352.5 0.1 4.1e-105 352.1 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KPA40081.1 - 1.5e-05 24.5 0.6 4e-05 23.1 0.1 2.1 2 1 0 2 2 2 1 Metalloenzyme superfamily DUF5615 PF18480.1 KPA40081.1 - 0.12 12.1 0.0 22 4.9 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) SET PF00856.28 KPA40082.1 - 5e-22 79.1 0.1 9.7e-22 78.1 0.0 1.5 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KPA40082.1 - 4.9e-08 33.7 1.4 7.5e-08 33.1 0.5 1.9 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding Adap_comp_sub PF00928.21 KPA40084.1 - 2.3e-91 305.8 0.0 4e-91 305.0 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KPA40084.1 - 1.3e-08 34.8 0.2 2.2e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KPA40084.1 - 0.11 11.9 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Opi1 PF08618.10 KPA40085.1 - 2.5e-43 148.9 15.3 1e-33 117.2 8.1 3.1 2 1 1 3 3 3 3 Transcription factor Opi1 ADH_N PF08240.12 KPA40086.1 - 3.7e-23 81.5 7.3 6.8e-23 80.6 7.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA40086.1 - 5.8e-19 68.4 0.2 1.7e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KPA40086.1 - 4.5e-05 22.8 0.1 8.7e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KPA40086.1 - 0.0011 18.3 0.2 0.0019 17.6 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KPA40086.1 - 0.0092 16.7 0.1 3 8.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain DJ-1_PfpI PF01965.24 KPA40087.1 - 6.5e-17 61.8 0.0 1.8e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KPA40087.1 - 6.5e-07 29.2 0.0 2.3e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like Catalase_C PF18011.1 KPA40087.1 - 0.00077 19.1 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases GATase_3 PF07685.14 KPA40087.1 - 0.025 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain FAP PF07174.11 KPA40088.1 - 5.1 6.5 34.4 7.6 5.9 34.4 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Porphobil_deam PF01379.20 KPA40089.1 - 2e-79 265.8 0.1 4e-79 264.9 0.0 1.5 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KPA40089.1 - 1.6e-17 63.6 0.8 3.8e-17 62.4 0.8 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GCV_H PF01597.19 KPA40090.1 - 5.9e-34 116.6 0.7 7.5e-34 116.2 0.7 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Pollen_allerg_1 PF01357.21 KPA40090.1 - 0.0074 16.3 0.6 0.13 12.3 0.0 2.2 1 1 1 2 2 2 1 Pollen allergen Ras PF00071.22 KPA40091.1 - 1.4e-31 109.3 0.1 1.7e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA40091.1 - 4e-24 85.1 0.1 7e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA40091.1 - 1.4e-06 27.9 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KPA40091.1 - 0.0004 19.8 0.1 0.00052 19.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KPA40091.1 - 0.0032 16.4 0.0 0.33 9.7 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) Fungal_trans_2 PF11951.8 KPA40094.1 - 1.2e-46 159.3 12.4 3.2e-46 157.9 12.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA40094.1 - 2.1e-10 40.5 12.6 3.8e-10 39.7 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Formyl_trans_N PF00551.19 KPA40095.1 - 2.6e-37 128.3 0.1 3.4e-37 127.9 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 KPA40095.1 - 3.2e-07 30.0 0.0 1.2e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KPA40095.1 - 0.0084 16.1 0.0 0.03 14.3 0.0 2.0 2 0 0 2 2 2 1 ACT domain ZnuA PF01297.17 KPA40095.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Thymidylate_kin PF02223.17 KPA40096.1 - 9.6e-40 136.2 0.0 5.9e-39 133.7 0.0 1.8 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 KPA40096.1 - 4.6e-05 23.7 0.0 9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KPA40096.1 - 0.0046 16.5 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KPA40096.1 - 0.055 14.0 0.0 0.17 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KPA40096.1 - 0.16 11.7 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PLAC8 PF04749.17 KPA40098.1 - 1e-07 32.8 0.2 2.7e-07 31.5 0.1 1.6 1 1 0 1 1 1 1 PLAC8 family SR-25 PF10500.9 KPA40098.1 - 1.6 8.3 7.8 2.6 7.6 7.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_12 PF13087.6 KPA40099.1 - 1.6e-24 86.7 0.0 2.5e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPA40099.1 - 3.9e-11 43.2 0.0 5.4e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KPA40099.1 - 1.2e-05 25.2 0.1 0.03 14.1 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KPA40099.1 - 0.00045 20.6 0.0 0.0019 18.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 KPA40099.1 - 0.032 14.1 0.1 0.18 11.7 0.0 2.2 3 0 0 3 3 3 0 Helicase AAA PF00004.29 KPA40099.1 - 0.092 13.2 0.1 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KPA40099.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KPA40099.1 - 0.12 12.7 0.0 0.99 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KPA40099.1 - 0.18 11.5 0.1 0.59 9.9 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Pyridox_ox_2 PF12900.7 KPA40100.1 - 4.2e-32 111.1 0.0 5.6e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SRP54 PF00448.22 KPA40101.1 - 2.7e-76 255.6 1.5 2.7e-76 255.6 1.5 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KPA40101.1 - 1.3e-30 105.9 4.1 1.3e-30 105.9 4.1 4.0 3 2 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KPA40101.1 - 1.7e-21 76.2 0.8 4.7e-21 74.8 0.8 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KPA40101.1 - 5.9e-07 29.2 0.6 3e-06 27.0 0.6 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KPA40101.1 - 6.8e-07 29.5 0.0 2.4e-06 27.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 KPA40101.1 - 5.8e-06 26.8 0.1 2.1e-05 25.0 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA40101.1 - 0.00017 22.0 0.0 0.00034 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KPA40101.1 - 0.00048 19.2 0.5 0.0038 16.3 0.5 2.4 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KPA40101.1 - 0.0012 18.6 0.1 0.0039 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KPA40101.1 - 0.0015 18.5 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 KPA40101.1 - 0.0032 16.8 0.0 0.0032 16.8 0.0 1.7 2 0 0 2 2 1 1 Zeta toxin ResIII PF04851.15 KPA40101.1 - 0.0032 17.5 0.3 0.04 13.9 0.3 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 KPA40101.1 - 0.0032 17.5 0.2 0.06 13.4 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase CbiA PF01656.23 KPA40101.1 - 0.0033 17.5 0.0 0.013 15.6 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KPA40101.1 - 0.0035 17.9 0.0 0.0077 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KPA40101.1 - 0.0037 17.0 0.2 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_22 PF13401.6 KPA40101.1 - 0.0048 17.2 0.0 0.016 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KPA40101.1 - 0.007 16.2 0.3 0.031 14.0 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KPA40101.1 - 0.011 15.1 0.7 2.9 7.3 0.8 3.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 KPA40101.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KPA40101.1 - 0.016 15.1 0.0 0.057 13.3 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 KPA40101.1 - 0.018 15.4 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KPA40101.1 - 0.046 13.6 1.2 0.84 9.5 1.2 2.3 1 1 0 1 1 1 0 NTPase 6PF2K PF01591.18 KPA40101.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.21 KPA40101.1 - 0.089 12.2 0.0 0.32 10.4 0.0 1.9 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_31 PF13614.6 KPA40101.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KPA40101.1 - 0.14 12.6 0.3 0.52 10.7 0.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKA2 PF16740.5 KPA40101.1 - 0.33 10.7 5.6 11 5.9 0.1 2.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Peptidase_M20 PF01546.28 KPA40102.1 - 6.3e-30 104.4 0.0 8.6e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPA40102.1 - 1.7e-09 37.6 0.0 3.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KPA40102.1 - 0.066 12.9 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 NUDIX PF00293.28 KPA40103.1 - 2.7e-13 50.1 1.0 5.5e-13 49.1 0.2 1.7 2 0 0 2 2 2 1 NUDIX domain TPR_10 PF13374.6 KPA40104.1 - 3.9e-28 96.5 0.1 4.9e-10 38.9 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPA40104.1 - 4.3e-24 84.6 0.0 4.1e-11 43.0 0.0 4.4 3 1 2 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 KPA40104.1 - 3.6e-10 39.5 0.0 1e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.6 KPA40104.1 - 2e-06 27.4 0.9 0.016 15.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KPA40104.1 - 3.6e-05 24.0 0.1 0.21 12.3 0.0 3.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPA40104.1 - 0.00053 20.6 0.0 1.7 9.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat NACHT PF05729.12 KPA40104.1 - 0.00072 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.17 KPA40104.1 - 0.0097 16.0 0.0 14 6.1 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 KPA40104.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 KPA40104.1 - 0.017 14.7 0.0 0.044 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_17 PF13431.6 KPA40104.1 - 0.049 14.0 0.0 11 6.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 KPA40104.1 - 0.11 12.8 0.0 0.44 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Helo_like_N PF17111.5 KPA40104.1 - 0.12 11.7 0.2 0.21 10.9 0.2 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins TPR_1 PF00515.28 KPA40104.1 - 0.19 11.6 0.0 12 5.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KPA40105.1 - 2.9e-14 52.9 0.5 2.1e-13 50.1 0.5 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily DUF1033 PF06279.11 KPA40105.1 - 0.15 12.2 0.9 0.3 11.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) NACHT PF05729.12 KPA40106.1 - 3.4e-08 33.6 0.0 8.8e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPA40106.1 - 0.00057 20.3 0.0 0.0018 18.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain WD40 PF00400.32 KPA40106.1 - 0.0016 19.2 0.3 0.008 17.0 0.3 2.2 1 0 0 1 1 1 1 WD domain, G-beta repeat AAA PF00004.29 KPA40106.1 - 0.051 14.0 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KPA40106.1 - 0.054 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KPA40106.1 - 0.11 12.6 0.2 0.48 10.5 0.2 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KPA40106.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.6 KPA40107.1 - 1.9e-16 60.4 0.0 2.9e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40107.1 - 3.9e-12 46.7 0.0 1.4e-11 45.0 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA40107.1 - 4.5e-11 43.2 0.0 9.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA40107.1 - 1.3e-07 32.2 0.0 4.3e-06 27.4 0.0 3.0 2 2 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA40107.1 - 8.9e-06 25.6 0.0 0.00026 20.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA40107.1 - 0.00061 19.2 0.0 0.022 14.1 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KPA40107.1 - 0.0027 17.1 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KPA40107.1 - 0.0045 16.5 0.0 0.0098 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KPA40107.1 - 0.0055 16.8 0.2 0.41 10.7 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KPA40107.1 - 0.0077 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 KPA40107.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KPA40107.1 - 0.036 13.5 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 KPA40107.1 - 0.072 12.4 0.0 0.33 10.2 0.0 2.0 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 KPA40107.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) SCA7 PF08313.12 KPA40110.1 - 2e-30 104.5 0.1 6.7e-30 102.8 0.1 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain Mito_carr PF00153.27 KPA40111.1 - 1.2e-43 147.0 3.2 5.6e-15 55.0 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein zf-NOSIP PF15906.5 KPA40112.1 - 1.2e-07 31.8 0.0 2.6e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 KPA40112.1 - 3.3e-06 26.9 5.3 3.3e-06 26.9 5.3 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPA40112.1 - 5.3e-06 26.4 12.8 3.7e-05 23.7 5.3 2.9 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 KPA40112.1 - 8.6e-06 26.0 13.5 0.00065 20.0 6.2 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 KPA40112.1 - 1.2e-05 25.0 11.5 0.0002 21.1 4.0 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPA40112.1 - 3.5e-05 23.9 15.7 0.014 15.5 8.3 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KPA40112.1 - 0.0052 16.6 14.8 0.015 15.2 6.9 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KPA40112.1 - 0.0072 16.4 12.3 0.018 15.2 3.9 2.9 3 1 0 3 3 3 2 FYVE zinc finger Siva PF05458.12 KPA40112.1 - 0.59 9.8 7.8 0.034 13.8 1.7 2.0 2 0 0 2 2 2 0 Cd27 binding protein (Siva) zf-RING_10 PF16685.5 KPA40112.1 - 9.5 6.4 15.5 0.11 12.6 3.4 2.8 3 0 0 3 3 3 0 zinc RING finger of MSL2 Acyltransferase PF01553.21 KPA40113.1 - 7.1e-12 45.1 0.0 1.6e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 KPA40114.1 - 3e-77 259.6 0.0 3.4e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40114.1 - 3e-38 131.6 0.0 4e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPA40114.1 - 0.0029 16.6 0.0 0.038 12.9 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KPA40114.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPA40114.1 - 0.12 12.3 1.4 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Septin PF00735.18 KPA40115.1 - 1.2e-13 50.9 0.0 3e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 KPA40115.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_24 PF13479.6 KPA40115.1 - 0.0047 16.7 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KPA40115.1 - 0.0094 16.0 0.0 0.26 11.4 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KPA40115.1 - 0.011 16.1 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KPA40115.1 - 0.024 14.9 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPA40115.1 - 0.028 15.0 0.0 0.066 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KPA40115.1 - 0.03 14.5 0.5 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KPA40115.1 - 0.05 14.1 0.0 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 KPA40115.1 - 0.074 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Roc PF08477.13 KPA40115.1 - 0.088 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase dNK PF01712.19 KPA40115.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase ATPase_2 PF01637.18 KPA40115.1 - 0.12 12.3 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KPA40115.1 - 0.13 12.2 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KPA40115.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AhpC-TSA_2 PF13911.6 KPA40116.1 - 1.5e-08 34.8 0.0 2.5e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KPA40116.1 - 5.6e-07 29.5 0.0 9.8e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPA40116.1 - 0.0011 18.7 0.0 0.039 13.6 0.0 2.1 1 1 1 2 2 2 2 Redoxin Tubulin_3 PF14881.6 KPA40117.1 - 7.3e-79 263.6 0.4 1.3e-78 262.9 0.1 1.5 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 KPA40117.1 - 1.6e-42 144.6 0.0 2.7e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KPA40117.1 - 4.7e-06 26.9 0.0 0.016 15.4 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain PAP_central PF04928.17 KPA40118.1 - 4e-109 363.4 0.0 5.3e-109 363.0 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KPA40118.1 - 7.4e-67 224.2 0.3 1.3e-66 223.5 0.3 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KPA40118.1 - 6.6e-10 39.2 0.1 1.6e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KPA40118.1 - 0.026 14.3 0.1 0.074 12.8 0.1 1.8 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain Forkhead PF00250.18 KPA40119.1 - 2.4e-35 120.6 0.3 4.5e-35 119.8 0.3 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KPA40119.1 - 2.6e-12 46.9 0.3 1.1e-11 45.0 0.2 2.1 1 1 1 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KPA40119.1 - 2.2e-05 24.7 0.0 4.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 KPA40119.1 - 0.09 13.0 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 FHA domain CLU PF13236.6 KPA40120.1 - 7.8e-76 254.8 0.0 2.1e-75 253.4 0.0 1.7 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 KPA40120.1 - 1.6e-56 191.1 0.0 4.1e-56 189.8 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KPA40120.1 - 2.1e-25 88.8 8.0 1.5e-11 44.4 0.3 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KPA40120.1 - 1.6e-22 78.7 1.5 2.1e-06 27.4 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.6 KPA40120.1 - 2.2e-22 79.2 0.0 6.6e-22 77.7 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_2 PF07719.17 KPA40120.1 - 0.00089 19.2 1.4 0.39 11.0 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF727 PF05303.12 KPA40120.1 - 0.00095 19.2 0.0 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 KPA40120.1 - 0.004 17.3 7.1 0.088 13.1 0.3 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF1682 PF07946.14 KPA40120.1 - 3.8 6.6 7.0 9 5.4 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MSC PF09402.10 KPA40121.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Ferric_reduct PF01794.19 KPA40122.1 - 4e-21 75.4 4.5 9.4e-21 74.2 4.5 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPA40122.1 - 1.5e-19 70.6 0.0 1e-16 61.4 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPA40122.1 - 4.2e-14 52.6 0.0 2.5e-12 46.9 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain Nuc_sug_transp PF04142.15 KPA40123.1 - 2.9e-08 33.2 0.0 4.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KPA40123.1 - 5.2e-08 33.1 24.7 0.00018 21.7 4.9 2.8 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KPA40123.1 - 7.9e-05 22.1 1.7 7.9e-05 22.1 1.7 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family DUF2613 PF11021.8 KPA40123.1 - 0.0037 17.3 0.9 0.54 10.4 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2613) PDR_assoc PF08370.11 KPA40123.1 - 0.68 9.7 7.2 3 7.6 0.2 3.0 3 0 0 3 3 3 0 Plant PDR ABC transporter associated DUF423 PF04241.15 KPA40123.1 - 1.5 9.0 7.5 0.75 10.0 1.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF423) Yippee-Mis18 PF03226.14 KPA40124.1 - 2.9e-16 59.6 0.4 3.3e-16 59.4 0.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KPA40124.1 - 0.0029 17.8 0.7 0.0044 17.2 0.7 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF2039 PF10217.9 KPA40124.1 - 0.018 15.3 1.3 0.085 13.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RNA_POL_M_15KD PF02150.16 KPA40124.1 - 0.045 13.6 1.2 8.1 6.4 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Evr1_Alr PF04777.13 KPA40124.1 - 0.14 12.6 0.9 2.4 8.7 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family DUF2985 PF11204.8 KPA40125.1 - 5.8e-39 132.1 1.2 5.8e-39 132.1 1.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Sen15 PF09631.10 KPA40126.1 - 3.4e-26 91.4 0.0 4.3e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein ADH_N PF08240.12 KPA40127.1 - 1.8e-29 101.8 4.1 2.7e-29 101.2 4.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA40127.1 - 2.7e-16 59.8 0.0 4.6e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPA40127.1 - 0.00013 21.6 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KPA40127.1 - 0.00073 18.9 0.0 0.00097 18.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KPA40127.1 - 0.012 16.6 0.0 0.069 14.2 0.0 2.2 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KPA40127.1 - 0.063 14.0 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MBOAT PF03062.19 KPA40129.1 - 4.1e-49 167.8 14.0 4.1e-49 167.8 14.0 2.3 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Fungal_trans PF04082.18 KPA40130.1 - 0.02 13.9 0.3 0.035 13.1 0.3 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KPA40131.1 - 9.8e-79 263.6 49.9 7.1e-42 143.2 21.6 2.9 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KPA40131.1 - 3e-37 126.4 4.8 2.1e-30 104.4 0.0 4.0 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 KPA40131.1 - 9.5e-36 123.3 0.0 1.7e-16 61.0 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KPA40131.1 - 1.3e-18 67.3 0.0 3.3e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KPA40131.1 - 7.7e-12 45.0 27.9 3.7e-07 29.6 8.8 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KPA40131.1 - 7.1e-07 29.3 0.4 8.3e-05 22.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KPA40131.1 - 1.8e-06 27.7 0.1 2.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA40131.1 - 1.4e-05 25.6 0.1 0.0074 16.7 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KPA40131.1 - 6.8e-05 23.1 0.1 0.022 14.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPA40131.1 - 0.00013 22.5 0.1 0.0087 16.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPA40131.1 - 0.00015 21.4 0.9 0.016 14.9 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KPA40131.1 - 0.00027 20.4 0.0 0.11 11.9 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPA40131.1 - 0.0011 18.9 0.0 1.4 8.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 KPA40131.1 - 0.0059 17.0 0.2 7.3 7.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPA40131.1 - 0.018 15.3 0.6 2.5 8.4 0.2 3.1 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KPA40131.1 - 0.019 14.6 0.3 0.21 11.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KPA40131.1 - 0.025 14.3 0.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KPA40131.1 - 0.026 14.4 1.4 2.4 8.1 0.2 3.1 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 KPA40131.1 - 0.03 14.0 0.1 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KPA40131.1 - 0.041 14.1 0.1 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KPA40131.1 - 0.15 11.8 0.2 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family 2OG-FeII_Oxy PF03171.20 KPA40133.1 - 0.0018 18.7 0.1 0.013 16.0 0.1 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KPA40133.1 - 0.019 15.7 0.0 0.033 14.9 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Zip PF02535.22 KPA40134.1 - 5.4e-52 177.1 2.5 7.7e-52 176.6 2.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2897 PF11446.8 KPA40134.1 - 4.3 7.3 7.1 11 6.0 7.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Thioredoxin_4 PF13462.6 KPA40135.1 - 1.4e-05 25.3 0.0 2.5e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Phage_TAC_6 PF09550.10 KPA40135.1 - 0.02 15.3 0.1 0.038 14.4 0.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC DSBA PF01323.20 KPA40135.1 - 0.039 13.7 4.1 0.69 9.7 0.5 3.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain TssN PF17555.2 KPA40136.1 - 2.8 7.2 5.3 0.91 8.8 0.6 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssN Fungal_trans PF04082.18 KPA40137.1 - 9.9e-10 37.9 0.0 1.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA40137.1 - 6.2e-07 29.4 9.6 1.3e-06 28.4 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4199 PF13858.6 KPA40137.1 - 0.017 15.5 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) FeS_assembly_P PF01883.19 KPA40139.1 - 3.4e-08 33.5 0.1 2e-07 31.1 0.1 2.2 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein GTP_EFTU PF00009.27 KPA40140.1 - 1.2e-45 155.4 0.0 1.8e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KPA40140.1 - 1.5e-34 119.2 6.4 3.5e-34 118.0 6.4 1.7 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KPA40140.1 - 1.3e-23 83.1 0.0 3.7e-23 81.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KPA40140.1 - 1.2e-18 66.9 0.0 3.4e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KPA40140.1 - 3.7e-09 36.8 0.0 8.6e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KPA40140.1 - 6.9e-07 29.3 0.1 5.1e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KPA40140.1 - 0.00037 20.6 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Thiolase_N PF00108.23 KPA40141.1 - 1.6e-94 316.1 1.4 2.2e-94 315.7 0.5 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPA40141.1 - 6.3e-46 155.0 0.8 4.7e-44 149.0 0.7 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KPA40141.1 - 3.2e-06 26.9 7.6 1.5e-05 24.7 0.7 3.1 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KPA40141.1 - 0.076 13.0 0.2 40 4.3 0.2 3.3 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Mito_carr PF00153.27 KPA40142.1 - 1.2e-64 214.3 2.7 3e-22 78.4 0.1 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein WD40 PF00400.32 KPA40142.1 - 2.4e-11 44.0 0.4 0.016 16.0 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Serine_protease PF18405.1 KPA40142.1 - 0.12 11.5 0.1 0.3 10.2 0.1 1.6 1 0 0 1 1 1 0 Gammaproteobacterial serine protease Abhydrolase_6 PF12697.7 KPA40143.1 - 4.8e-10 40.4 0.0 5.9e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA40143.1 - 1.4e-05 24.8 0.1 5.8e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KPA40143.1 - 0.00064 19.9 0.0 0.00098 19.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain BAAT_C PF08840.11 KPA40143.1 - 0.033 14.1 0.0 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase PF07224.11 KPA40143.1 - 0.073 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.8 KPA40143.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ndr PF03096.14 KPA40143.1 - 0.17 10.6 0.0 0.51 9.0 0.0 1.8 1 1 0 1 1 1 0 Ndr family F-box-like PF12937.7 KPA40144.1 - 1.7e-10 40.6 0.0 4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA40144.1 - 0.00035 20.4 0.2 0.0012 18.7 0.2 1.9 1 0 0 1 1 1 1 F-box domain SOCS PF12610.8 KPA40145.1 - 0.1 13.0 0.1 0.1 13.0 0.1 2.7 3 0 0 3 3 3 0 Suppressor of cytokine signalling Cation_efflux PF01545.21 KPA40146.1 - 4e-20 72.4 8.3 5.1e-20 72.1 8.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KPA40146.1 - 0.00013 22.0 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter K_oxygenase PF13434.6 KPA40147.1 - 2.1e-15 56.8 0.0 8.7e-10 38.3 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPA40147.1 - 4.5e-09 36.0 0.0 0.089 12.0 0.0 3.2 2 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA40147.1 - 1.4e-07 31.0 0.0 0.00037 19.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA40147.1 - 0.00042 20.0 1.0 0.15 11.6 3.1 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KPA40147.1 - 0.0081 15.4 0.5 0.063 12.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KPA40147.1 - 0.0099 15.9 0.0 0.73 9.8 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KPA40147.1 - 0.091 11.4 0.0 2 7.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 KPA40147.1 - 0.11 12.6 0.0 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KPA40147.1 - 0.11 12.7 0.1 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPA40147.1 - 0.12 11.3 0.1 0.29 10.1 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein RTA1 PF04479.13 KPA40148.1 - 2e-50 171.3 12.3 2e-50 171.3 12.3 1.7 2 0 0 2 2 2 1 RTA1 like protein Zn_clus PF00172.18 KPA40148.1 - 2.7e-05 24.2 10.7 5.1e-05 23.3 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Erv26 PF04148.13 KPA40151.1 - 1.5e-91 305.8 1.1 1.8e-91 305.5 1.1 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3377 PF11857.8 KPA40151.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) WBS_methylT PF12589.8 KPA40152.1 - 1.7e-14 54.3 2.4 3.2e-14 53.5 2.4 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KPA40152.1 - 1.4e-10 41.7 0.0 2.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40152.1 - 1.2e-09 38.7 0.0 2.9e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KPA40152.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KPA40152.1 - 0.00035 21.3 0.0 0.0011 19.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA40152.1 - 0.0014 18.4 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA40152.1 - 0.0026 17.6 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KPA40152.1 - 0.0039 16.5 0.0 0.092 12.0 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KPA40152.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain TENA_THI-4 PF03070.16 KPA40153.1 - 0.0069 16.2 0.0 0.98 9.2 0.0 2.3 2 0 0 2 2 2 2 TENA/THI-4/PQQC family zf-LITAF-like PF10601.9 KPA40154.1 - 0.018 15.3 0.2 0.025 14.8 0.2 1.2 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain LST1 PF05083.13 KPA40154.1 - 0.033 14.5 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 LST-1 protein VSP PF03302.13 KPA40154.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein OFCC1 PF15680.5 KPA40155.1 - 0.2 12.2 0.0 0.36 11.4 0.0 1.4 1 0 0 1 1 1 0 Orofacial cleft 1 candidate gene 1 protein MFS_1 PF07690.16 KPA40156.1 - 1.4e-34 119.6 22.4 1.4e-34 119.6 22.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily AtuA PF07287.11 KPA40157.1 - 7e-126 419.7 0.1 8.6e-126 419.4 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA PUCC PF03209.15 KPA40157.1 - 0.35 9.8 0.6 0.53 9.2 0.6 1.1 1 0 0 1 1 1 0 PUCC protein Iso_dh PF00180.20 KPA40158.1 - 6.9e-81 272.1 0.0 8.8e-81 271.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.25 KPA40159.1 - 6.3e-70 235.6 0.0 8.8e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40159.1 - 4.5e-52 176.9 0.0 7.3e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPA40159.1 - 0.00075 18.4 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KPA40159.1 - 0.011 15.1 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like ABC1 PF03109.16 KPA40159.1 - 0.026 14.7 0.0 0.09 12.9 0.0 1.9 2 0 0 2 2 2 0 ABC1 family Haspin_kinase PF12330.8 KPA40159.1 - 0.16 10.8 0.0 1.1 8.1 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain Thioredoxin_7 PF13899.6 KPA40161.1 - 1.4e-15 57.2 0.0 3.3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KPA40161.1 - 1.9e-14 53.2 0.1 3.7e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KPA40161.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 KPA40161.1 - 0.013 16.0 0.0 0.03 14.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredox_DsbH PF03190.15 KPA40161.1 - 0.046 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DUF4484 PF14831.6 KPA40161.1 - 0.056 13.5 0.7 0.17 11.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Ecm29 PF13001.7 KPA40162.1 - 8.8e-144 479.9 2.4 2.2e-143 478.5 0.3 2.8 3 0 0 3 3 3 1 Proteasome stabiliser HEAT_EZ PF13513.6 KPA40162.1 - 0.0003 21.2 12.2 4.9 7.8 0.1 8.0 8 1 1 9 9 9 2 HEAT-like repeat HEAT PF02985.22 KPA40162.1 - 0.0041 17.3 9.5 11 6.7 0.0 8.0 9 0 0 9 9 9 1 HEAT repeat Tom22 PF04281.13 KPA40162.1 - 0.077 12.8 0.1 0.077 12.8 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 IPP-2 PF04979.14 KPA40162.1 - 0.11 13.3 0.3 0.3 11.8 0.3 1.7 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) Condensin2nSMC PF12422.8 KPA40162.1 - 0.29 11.3 2.0 17 5.5 0.1 3.7 3 1 1 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit HEAT_2 PF13646.6 KPA40162.1 - 0.82 10.1 4.8 54 4.3 0.0 5.2 6 0 0 6 6 6 0 HEAT repeats RRM_1 PF00076.22 KPA40163.1 - 2.7e-44 148.8 0.0 2.1e-16 59.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPA40163.1 - 2.7e-05 24.1 0.1 0.0034 17.3 0.1 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KPA40163.1 - 0.00018 21.6 0.1 0.079 13.1 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 KPA40163.1 - 0.00031 20.7 0.0 0.0027 17.7 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 KPA40163.1 - 0.00051 19.8 0.0 0.08 12.8 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KPA40163.1 - 0.095 12.3 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TatD_DNase PF01026.21 KPA40164.1 - 4.1e-43 147.6 0.0 5.1e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Cyclase PF04199.13 KPA40165.1 - 2.3e-16 60.3 0.0 3.2e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Sterol_MT_C PF08498.10 KPA40166.1 - 6.9e-29 100.0 0.1 1.1e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KPA40166.1 - 2.2e-22 79.5 0.0 4.1e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40166.1 - 2.3e-20 73.1 0.0 5.5e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA40166.1 - 2.4e-18 66.4 0.0 4e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA40166.1 - 2.6e-12 46.9 0.0 4.1e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA40166.1 - 4.1e-12 45.9 0.0 7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KPA40166.1 - 4.7e-12 45.8 0.0 6.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KPA40166.1 - 2.6e-10 40.9 0.0 7.4e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KPA40166.1 - 0.00018 20.2 0.0 0.00032 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 KPA40166.1 - 0.0067 16.2 0.1 0.017 14.9 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KPA40166.1 - 0.0088 15.5 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KPA40166.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 KPA40166.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 KPA40166.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_8 PF05148.15 KPA40166.1 - 0.033 14.1 0.1 0.11 12.3 0.0 1.9 3 0 0 3 3 3 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 KPA40166.1 - 0.038 13.3 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain RrnaAD PF00398.20 KPA40166.1 - 0.041 12.9 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 KPA40166.1 - 0.11 12.7 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase CFEM PF05730.11 KPA40168.1 - 4.6e-13 49.0 9.5 1e-12 47.9 9.5 1.6 1 0 0 1 1 1 1 CFEM domain DUF4362 PF14275.6 KPA40168.1 - 0.028 14.7 2.5 22 5.4 0.0 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4362) Perilipin PF03036.16 KPA40170.1 - 0.00012 21.3 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Perilipin family CPT PF07931.12 KPA40171.1 - 0.0095 15.8 0.0 0.03 14.2 0.0 1.9 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein DENN PF02141.21 KPA40172.1 - 2.7e-40 138.3 0.1 5.1e-40 137.4 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KPA40172.1 - 1.8e-07 31.8 0.1 8.9e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 uDENN domain Dfp1_Him1_M PF08630.10 KPA40172.1 - 0.15 12.3 2.1 24 5.1 3.4 2.5 2 0 0 2 2 2 0 Dfp1/Him1, central region DUF2570 PF10828.8 KPA40172.1 - 0.82 9.5 11.1 0.47 10.3 7.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) BRE1 PF08647.11 KPA40172.1 - 0.98 9.5 17.8 2.4 8.3 7.0 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase HAP1_N PF04849.13 KPA40172.1 - 7.2 5.7 22.7 0.16 11.1 9.3 3.1 3 0 0 3 3 3 0 HAP1 N-terminal conserved region zf-HIT PF04438.16 KPA40173.1 - 1.1e-09 38.0 9.4 1.5e-09 37.5 9.4 1.2 1 0 0 1 1 1 1 HIT zinc finger Pox_Ag35 PF03286.14 KPA40173.1 - 1.3 8.8 7.3 3 7.6 6.9 1.9 2 1 0 2 2 2 0 Pox virus Ag35 surface protein Sec6 PF06046.13 KPA40174.1 - 2.2e-162 541.4 9.6 3.4e-162 540.8 9.6 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KPA40174.1 - 0.00018 20.6 1.2 0.00018 20.6 1.2 2.1 2 1 0 2 2 2 1 Vps53-like, N-terminal FAD_binding_2 PF00890.24 KPA40174.1 - 0.0025 17.0 0.1 0.0066 15.6 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain SPATA19 PF15212.6 KPA40174.1 - 0.054 13.7 0.1 0.41 10.9 0.1 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated protein 19, mitochondrial OmdA PF13376.6 KPA40174.1 - 0.062 13.3 0.0 0.27 11.3 0.0 2.2 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated EF-hand_4 PF12763.7 KPA40175.1 - 2e-34 117.7 0.0 9.3e-14 51.2 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KPA40175.1 - 2e-08 34.5 0.0 3e-05 24.4 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KPA40175.1 - 2.9e-06 26.4 0.0 0.33 10.6 0.0 4.3 4 0 0 4 4 4 2 EF hand UBA PF00627.31 KPA40175.1 - 3.4e-05 23.6 0.0 7.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.6 KPA40175.1 - 0.00017 21.2 0.0 9.9 6.4 0.0 4.2 4 0 0 4 4 4 0 EF-hand domain TPR_MLP1_2 PF07926.12 KPA40175.1 - 0.0038 17.3 39.5 0.11 12.6 18.8 3.2 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 KPA40175.1 - 0.041 14.1 27.6 2 8.6 1.2 3.3 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 KPA40175.1 - 0.051 14.5 34.0 0.053 14.4 5.3 3.5 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain GAS PF13851.6 KPA40175.1 - 0.051 12.9 32.8 0.034 13.5 8.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Hemagglutinin PF00509.18 KPA40175.1 - 0.088 11.2 3.7 0.095 11.1 1.5 1.8 2 0 0 2 2 2 0 Haemagglutinin DUF3584 PF12128.8 KPA40175.1 - 0.26 8.8 33.1 0.36 8.3 33.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KPA40175.1 - 0.57 9.0 33.2 1.7 7.4 9.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 KPA40175.1 - 0.88 9.6 40.9 0.84 9.7 13.4 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 KPA40175.1 - 0.99 8.9 18.4 1.9 8.0 18.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4201 PF13870.6 KPA40175.1 - 1.1 8.9 30.7 0.83 9.4 20.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) BRE1 PF08647.11 KPA40175.1 - 1.1 9.3 27.2 1.1 9.4 1.1 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase HMMR_N PF15905.5 KPA40175.1 - 2.6 7.4 29.5 5.5 6.4 29.5 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Tup_N PF08581.10 KPA40175.1 - 2.8 8.3 18.0 0.47 10.8 7.3 2.7 1 1 1 2 2 2 0 Tup N-terminal Csm1_N PF18504.1 KPA40175.1 - 3.2 8.1 28.0 0.14 12.5 1.6 3.9 3 1 1 4 4 4 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 KPA40175.1 - 4.2 7.6 26.1 8.1 6.7 6.2 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.15 KPA40175.1 - 4.3 7.7 30.7 2.1e+02 2.2 28.4 2.3 1 1 1 2 2 2 0 Fez1 Golgin_A5 PF09787.9 KPA40175.1 - 4.4 6.7 33.0 2 7.8 7.3 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 LPP PF04728.13 KPA40175.1 - 6.5 7.2 13.2 1.5 9.3 3.5 3.3 3 1 0 3 3 2 0 Lipoprotein leucine-zipper SOGA PF11365.8 KPA40175.1 - 7.3 7.8 20.2 1.9 9.7 1.5 3.0 1 1 1 2 2 2 0 Protein SOGA FUSC PF04632.12 KPA40175.1 - 9.1 4.7 12.5 15 4.0 12.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.9 KPA40175.1 - 9.1 6.3 31.9 1.1 9.2 8.9 2.8 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 KPA40175.1 - 9.2 6.0 26.6 7.2 6.4 10.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 KPA40175.1 - 9.7 6.3 16.4 3 7.9 7.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pyr_redox_2 PF07992.14 KPA40176.1 - 2.6e-62 210.7 1.4 3.6e-62 210.2 1.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KPA40176.1 - 1.9e-33 115.0 0.7 1.5e-32 112.1 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KPA40176.1 - 2.7e-24 85.5 0.7 1.7e-20 73.3 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA40176.1 - 2e-14 53.5 0.5 2.8e-14 53.1 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA40176.1 - 1.3e-06 27.8 0.0 0.00026 20.2 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KPA40176.1 - 3e-05 22.9 4.9 0.038 12.7 0.1 3.1 2 1 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 KPA40176.1 - 0.00058 19.2 1.0 0.35 10.1 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KPA40176.1 - 0.0018 17.6 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family 2-Hacid_dh_C PF02826.19 KPA40176.1 - 0.0062 15.9 0.5 0.33 10.3 0.1 3.2 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ntox47 PF15540.6 KPA40176.1 - 0.0066 16.7 0.4 0.02 15.2 0.1 2.0 2 0 0 2 2 1 1 Bacterial toxin 47 FAD_oxidored PF12831.7 KPA40176.1 - 0.008 15.6 0.1 0.02 14.2 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KPA40176.1 - 0.012 14.7 0.0 0.062 12.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.24 KPA40176.1 - 0.019 14.6 4.9 0.084 12.4 0.1 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA40176.1 - 0.024 14.9 0.4 0.024 14.9 0.4 2.0 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KPA40176.1 - 0.04 13.8 0.0 0.04 13.8 0.0 2.5 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KPA40176.1 - 0.085 12.1 0.4 1.4 8.0 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain Aminotran_1_2 PF00155.21 KPA40177.1 - 4.9e-43 147.7 0.0 6e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ecl1 PF12855.7 KPA40178.1 - 2.4e-13 51.6 29.3 3e-13 51.3 29.3 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins DUF2116 PF09889.9 KPA40178.1 - 0.18 11.8 2.8 0.22 11.5 0.5 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PLATZ PF04640.14 KPA40178.1 - 0.74 10.5 7.4 0.12 13.0 2.7 2.1 2 1 0 2 2 2 0 PLATZ transcription factor Abhydrolase_3 PF07859.13 KPA40179.1 - 3.6e-39 134.8 0.0 5.6e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPA40179.1 - 0.00017 20.6 0.0 0.00092 18.2 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KPA40179.1 - 0.00061 20.5 0.0 0.00082 20.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Actino_peptide PF14408.6 KPA40181.1 - 3.1 8.0 7.7 5.9 7.1 0.2 2.7 2 2 1 3 3 3 0 Ribosomally synthesised peptide in actinomycetes FYDLN_acid PF09538.10 KPA40182.1 - 4.6 8.0 8.2 12 6.6 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Macro PF01661.21 KPA40183.1 - 6e-13 48.9 0.0 8.7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Macro domain DSS1_SEM1 PF05160.13 KPA40184.1 - 2.1e-24 85.3 14.9 2.9e-24 84.9 14.9 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.19 KPA40186.1 - 1.2e-152 508.3 1.7 1.3e-152 508.1 1.7 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 KPA40186.1 - 0.00065 19.7 0.7 0.17 11.9 0.0 3.2 3 1 0 3 3 3 1 PA domain ADH_zinc_N PF00107.26 KPA40186.1 - 0.0022 18.0 0.1 0.098 12.6 0.1 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PrpR_N PF06506.11 KPA40186.1 - 0.039 13.5 1.3 1.8 8.1 0.1 3.3 3 1 0 3 3 3 0 Propionate catabolism activator FIVAR PF07554.13 KPA40186.1 - 5 8.0 5.5 17 6.3 0.6 3.3 3 1 0 3 3 3 0 FIVAR domain HMGL-like PF00682.19 KPA40187.1 - 2.7e-78 263.2 0.4 3.9e-78 262.6 0.4 1.3 1 0 0 1 1 1 1 HMGL-like Mpv17_PMP22 PF04117.12 KPA40188.1 - 2.1e-20 72.7 0.1 2.1e-20 72.7 0.1 2.4 3 0 0 3 3 3 1 Mpv17 / PMP22 family NACHT PF05729.12 KPA40189.1 - 0.0024 17.8 0.1 0.0092 15.9 0.0 2.0 2 0 0 2 2 2 1 NACHT domain ALIX_LYPXL_bnd PF13949.6 KPA40189.1 - 0.11 11.8 2.1 0.69 9.2 0.0 2.5 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Kinesin PF00225.23 KPA40190.1 - 1.9e-56 191.4 0.0 4.1e-56 190.3 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPA40190.1 - 5.1e-11 42.7 0.0 2.5e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding Herpes_BLRF2 PF05812.12 KPA40190.1 - 0.011 15.8 5.7 0.038 14.1 0.3 2.6 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF3772 PF12607.8 KPA40190.1 - 0.057 13.2 3.5 7.6 6.4 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) TSC22 PF01166.18 KPA40190.1 - 0.12 12.7 1.5 0.26 11.6 0.1 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family RIX1 PF08167.12 KPA40190.1 - 0.15 11.8 0.7 0.26 11.0 0.7 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis bZIP_2 PF07716.15 KPA40190.1 - 0.34 11.0 7.2 1.1 9.3 0.8 2.8 2 0 0 2 2 2 0 Basic region leucine zipper Peptidase_S24 PF00717.23 KPA40193.1 - 4.2e-07 29.8 0.1 6.3e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like CsbD PF05532.12 KPA40194.1 - 7e-08 32.3 10.1 0.0001 22.1 1.8 2.2 2 0 0 2 2 2 2 CsbD-like PalH PF08733.10 KPA40195.1 - 0.005 15.9 4.7 0.005 15.9 4.7 1.8 2 0 0 2 2 2 1 PalH/RIM21 BTB PF00651.31 KPA40196.1 - 6.8e-08 32.7 0.0 3.3e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 KPA40196.1 - 0.00065 19.8 0.0 0.017 15.3 0.0 2.3 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain EPO_TPO PF00758.18 KPA40196.1 - 0.038 14.0 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin DUF1349 PF07081.11 KPA40197.1 - 6e-20 71.7 0.1 8e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) TFIIB PF00382.19 KPA40198.1 - 1.7e-30 104.9 2.3 2.6e-19 69.0 0.1 2.8 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KPA40198.1 - 6e-25 87.5 3.8 6e-25 87.5 3.8 3.4 4 0 0 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 KPA40198.1 - 7.9e-05 22.4 1.0 0.02 14.6 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF365 PF04033.12 KPA40198.1 - 0.13 12.5 0.4 0.43 10.9 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Rtf2 PF04641.12 KPA40198.1 - 2 7.7 7.1 0.76 9.1 3.0 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger CorA PF01544.18 KPA40200.1 - 0.023 14.0 0.1 0.037 13.4 0.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ADH_zinc_N PF00107.26 KPA40202.1 - 4.9e-14 52.4 0.1 9e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA40202.1 - 2.8e-09 36.8 0.0 6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KPA40202.1 - 8.8e-05 22.4 0.0 0.00028 20.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase 3HCDH_N PF02737.18 KPA40203.1 - 9.4e-34 116.9 0.0 2.8e-33 115.3 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KPA40203.1 - 2e-09 37.9 0.0 4.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ldh_1_N PF00056.23 KPA40203.1 - 0.082 13.0 0.1 1.3 9.1 0.1 2.6 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain HET PF06985.11 KPA40204.1 - 3.7e-23 82.5 0.1 6.3e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Stc1 PF12898.7 KPA40205.1 - 4.5e-16 59.2 7.4 4.5e-16 59.2 7.4 1.7 2 0 0 2 2 2 1 Stc1 domain BCDHK_Adom3 PF10436.9 KPA40206.1 - 1.7e-75 252.3 0.0 2.4e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KPA40206.1 - 2.7e-10 40.7 0.0 4.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KPA40206.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NBP1 PF08537.10 KPA40207.1 - 0.01 15.3 3.1 0.01 15.3 3.1 2.1 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 DUF2203 PF09969.9 KPA40207.1 - 0.15 12.8 5.6 0.055 14.2 2.7 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) ImcF-related_N PF14331.6 KPA40207.1 - 0.2 11.0 2.1 0.15 11.4 0.4 1.6 2 0 0 2 2 2 0 ImcF-related N-terminal domain DUF4972 PF16342.5 KPA40207.1 - 0.22 11.2 0.9 53 3.5 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4972) HMMR_N PF15905.5 KPA40207.1 - 0.23 10.9 5.7 0.37 10.2 5.7 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Seryl_tRNA_N PF02403.22 KPA40207.1 - 0.32 11.2 6.2 2.3 8.5 5.7 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 KPA40207.1 - 0.35 10.1 2.2 0.53 9.5 2.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Tropomyosin_1 PF12718.7 KPA40207.1 - 0.62 10.2 8.7 0.27 11.4 6.0 1.8 2 0 0 2 2 2 0 Tropomyosin like DUF4094 PF13334.6 KPA40207.1 - 0.76 10.2 5.6 3.2 8.2 3.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) LPP PF04728.13 KPA40207.1 - 1.1 9.7 7.3 0.51 10.8 3.2 2.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Snapin_Pallidin PF14712.6 KPA40207.1 - 1.1 9.7 10.4 1.1 9.8 6.8 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Exonuc_VII_L PF02601.15 KPA40207.1 - 1.5 8.3 4.7 1.4 8.5 2.0 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit FapA PF03961.13 KPA40207.1 - 2.5 6.6 5.0 3.6 6.1 5.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Swi5 PF07061.11 KPA40207.1 - 2.7 8.1 6.7 23 5.2 1.4 2.6 2 0 0 2 2 2 0 Swi5 ATG16 PF08614.11 KPA40207.1 - 3.8 7.7 12.2 8.9 6.5 7.2 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CENP-H PF05837.12 KPA40207.1 - 4.4 7.7 10.3 1.7 9.0 4.8 2.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) CofC PF01983.16 KPA40208.1 - 0.11 11.6 0.3 5.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Guanylyl transferase CofC like RCC_reductase PF06405.11 KPA40208.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) SRP-alpha_N PF04086.13 KPA40208.1 - 2.9 7.7 19.8 0.25 11.3 7.3 2.4 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Pyridoxal_deC PF00282.19 KPA40209.1 - 9e-18 64.1 0.0 1.4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KPA40209.1 - 3.7e-06 26.1 0.0 1.1e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KPA40209.1 - 2.4e-05 23.8 0.0 3.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_34 PF05637.12 KPA40210.1 - 1.7e-69 234.2 0.1 2.1e-69 233.9 0.1 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KPA40210.1 - 3.2e-05 23.6 0.0 0.14 11.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF273 RINGv PF12906.7 KPA40211.1 - 1.8e-09 37.5 4.2 1.8e-08 34.4 1.1 2.4 2 0 0 2 2 2 1 RING-variant domain zf-MIZ PF02891.20 KPA40211.1 - 0.01 15.5 2.0 0.022 14.5 2.0 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF202 PF02656.15 KPA40211.1 - 0.13 12.7 2.8 0.15 12.5 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) PHD_4 PF16866.5 KPA40211.1 - 0.15 12.2 5.5 2 8.5 5.9 2.2 1 1 1 2 2 2 0 PHD-finger PHD PF00628.29 KPA40211.1 - 1.7 8.6 7.4 0.19 11.7 2.8 1.7 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.26 KPA40212.1 - 4.4e-57 192.7 0.1 6.4e-34 117.1 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KPA40212.1 - 1.2e-10 40.9 0.3 3.1e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.15 KPA40212.1 - 0.012 14.4 0.2 2.5 6.7 0.1 2.1 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family RCC1_2 PF13540.6 KPA40213.1 - 2.6e-12 46.2 3.1 0.00015 21.4 0.1 3.8 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KPA40213.1 - 1.4e-10 41.6 0.2 0.0037 17.9 0.0 4.8 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Ribonuclease_3 PF00636.26 KPA40214.1 - 6.5e-38 129.6 0.0 7e-21 74.8 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KPA40214.1 - 1.3e-22 80.3 0.0 1.8e-08 34.6 0.0 4.2 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KPA40214.1 - 3.8e-22 78.2 0.0 2.4e-21 75.7 0.0 2.5 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KPA40214.1 - 6.8e-16 58.6 0.1 2.2e-15 57.0 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPA40214.1 - 3.1e-09 36.8 0.2 0.0016 18.3 0.0 2.8 1 1 1 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KPA40214.1 - 1.2e-05 25.4 0.0 0.13 12.3 0.0 2.4 1 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KPA40215.1 - 0.00045 20.8 0.0 0.00086 19.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 KPA40215.1 - 0.00063 19.6 0.0 0.00095 19.0 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 KPA40215.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 KPA40215.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 KPA40215.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KPA40215.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 KPA40215.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase Glyco_transf_64 PF09258.10 KPA40216.1 - 3.6e-49 167.3 0.0 5.7e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain PTH2 PF01981.16 KPA40216.1 - 5.3e-46 155.7 0.2 1.1e-45 154.7 0.2 1.6 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Glycos_transf_2 PF00535.26 KPA40216.1 - 0.0089 15.8 0.3 0.059 13.2 0.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KPA40216.1 - 0.025 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 BING4CT PF08149.11 KPA40217.1 - 4.5e-41 138.5 0.0 2.3e-36 123.4 0.0 3.6 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.32 KPA40217.1 - 3.3e-07 30.9 0.0 0.025 15.5 0.0 4.6 3 1 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA40217.1 - 4.2e-06 27.0 0.9 5 7.5 0.0 5.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KPA40217.1 - 5.2e-05 22.5 0.1 0.00053 19.1 0.0 2.0 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 KPA40217.1 - 0.018 14.9 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A RIBIOP_C PF04950.12 KPA40218.1 - 5.9e-106 354.2 0.0 1.3e-105 353.0 0.0 1.6 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KPA40218.1 - 1.6e-17 63.3 0.0 4.3e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.19 KPA40219.1 - 2.3e-33 115.2 0.0 4.7e-33 114.2 0.0 1.5 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KPA40219.1 - 5.6e-05 22.3 0.1 0.025 13.6 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KPA40219.1 - 0.013 15.6 0.0 0.08 13.0 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KPA40219.1 - 0.021 15.3 0.0 0.032 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KPA40219.1 - 0.039 13.8 0.0 0.061 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 KPA40219.1 - 0.089 12.5 0.1 0.35 10.6 0.0 1.9 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family TIP49 PF06068.13 KPA40219.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_16 PF13191.6 KPA40219.1 - 0.13 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KPA40219.1 - 0.2 11.6 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Nrap_D4 PF17405.2 KPA40220.1 - 0.05 13.0 0.0 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 Nrap protein nucleotidyltransferase domain 4 DUF3437 PF11919.8 KPA40222.1 - 0.53 10.2 2.6 22 5.1 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3437) DUF1690 PF07956.11 KPA40222.1 - 3.1 8.2 12.1 9.7 6.6 3.6 2.5 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Ras PF00071.22 KPA40223.1 - 1.2e-55 187.6 0.0 1.4e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA40223.1 - 7.8e-22 77.7 0.0 1.2e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA40223.1 - 4.9e-07 29.4 0.0 7.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KPA40223.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KPA40223.1 - 0.11 11.7 0.1 1 8.5 0.0 2.1 1 1 1 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 KPA40223.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region adh_short PF00106.25 KPA40224.1 - 1.8e-20 73.3 0.0 3.7e-15 55.9 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA40224.1 - 4e-13 49.5 0.1 2.5e-11 43.6 0.0 2.7 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_18 PF00704.28 KPA40225.1 - 2.9e-31 109.4 0.0 3.7e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1266 PF06889.11 KPA40225.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF1996 PF09362.10 KPA40226.1 - 1.5e-72 244.4 1.7 2.8e-72 243.5 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 KPA40226.1 - 6.7e-69 228.1 79.2 1.3e-19 70.1 13.9 4.9 5 0 0 5 5 5 4 WSC domain Pkinase PF00069.25 KPA40228.1 - 2.5e-64 217.2 0.0 3.4e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40228.1 - 1.3e-38 132.7 0.0 2e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA40228.1 - 4.7e-08 32.7 0.0 1e-07 31.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KPA40228.1 - 6.9e-05 22.0 0.4 6.9e-05 22.0 0.4 1.9 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KPA40228.1 - 0.031 14.2 0.2 0.031 14.2 0.2 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KPA40228.1 - 0.048 13.0 0.3 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KPA40228.1 - 0.082 11.9 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 KPA40228.1 - 0.13 11.8 0.5 0.95 9.0 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Ilm1 PF10311.9 KPA40229.1 - 2.5e-63 212.6 0.6 2.9e-63 212.4 0.6 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.21 KPA40230.1 - 2e-31 107.4 6.1 2.9e-06 26.9 1.6 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KPA40230.1 - 0.0032 16.6 0.0 0.024 13.7 0.0 2.2 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain MTCP1 PF08991.10 KPA40230.1 - 0.044 14.0 1.0 0.079 13.2 1.0 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type CHCH PF06747.13 KPA40230.1 - 0.43 10.8 5.9 1 9.6 5.9 1.7 1 0 0 1 1 1 0 CHCH domain TMEM154 PF15102.6 KPA40231.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF5392 PF17370.2 KPA40231.1 - 0.24 11.5 0.8 20 5.3 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5392) NatB_MDM20 PF09797.9 KPA40232.1 - 1.2e-43 149.5 0.0 3e-43 148.2 0.0 1.6 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF604 PF04646.12 KPA40233.1 - 4e-10 39.5 0.2 6.4e-10 38.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 KPA40233.1 - 1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Cu2_monoox_C PF03712.15 KPA40233.1 - 0.2 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DUF3445 PF11927.8 KPA40234.1 - 1.4e-76 257.1 0.0 1.7e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans PF04082.18 KPA40236.1 - 2.2e-12 46.6 0.1 3.5e-12 45.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA40236.1 - 5.8e-06 26.3 13.6 1.3e-05 25.2 13.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.18 KPA40236.1 - 3.4 8.0 5.4 0.85 9.9 0.3 2.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper adh_short PF00106.25 KPA40237.1 - 7.2e-22 77.8 0.0 1.1e-18 67.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA40237.1 - 5.7e-13 49.0 0.0 1.1e-12 48.0 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPA40237.1 - 3.6e-06 26.6 0.1 8.2e-06 25.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPA40237.1 - 0.0026 17.7 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KPA40237.1 - 0.0071 15.8 0.4 0.022 14.1 0.4 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KPA40237.1 - 0.014 14.7 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SWIB PF02201.18 KPA40238.1 - 4.9e-30 103.2 1.3 7.2e-30 102.7 0.5 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 KPA40238.1 - 8e-16 57.7 2.1 1.7e-15 56.6 0.7 2.1 2 0 0 2 2 2 1 DEK C terminal domain FliT PF05400.13 KPA40238.1 - 0.092 13.6 2.8 0.43 11.4 0.5 2.6 2 0 0 2 2 2 0 Flagellar protein FliT Macoilin PF09726.9 KPA40238.1 - 0.28 9.7 4.3 0.3 9.6 4.3 1.1 1 0 0 1 1 1 0 Macoilin family MCM2_N PF12619.8 KPA40238.1 - 2.9 8.2 7.6 3 8.1 0.9 2.7 1 1 1 2 2 2 0 Mini-chromosome maintenance protein 2 zf-C3HC4_3 PF13920.6 KPA40239.1 - 3.4e-06 26.8 8.6 3.4e-06 26.8 8.6 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ribonuc_2-5A PF06479.12 KPA40240.1 - 7.9e-42 142.4 0.0 1.6e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KPA40240.1 - 1.1e-41 142.9 0.0 1.3e-40 139.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40240.1 - 5.3e-21 75.1 0.0 2.9e-20 72.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 KPA40240.1 - 9.6e-06 25.3 3.9 0.0092 15.9 0.0 3.9 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_2 PF13360.6 KPA40240.1 - 0.00053 19.6 0.1 0.0072 15.9 0.1 2.5 1 1 1 2 2 2 2 PQQ-like domain Kdo PF06293.14 KPA40240.1 - 0.00076 18.9 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KPA40240.1 - 0.0018 17.1 1.2 0.0037 16.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KPA40240.1 - 0.0067 16.4 0.2 0.029 14.3 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KPA40240.1 - 0.046 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Neur_chan_memb PF02932.16 KPA40240.1 - 0.1 12.6 5.8 0.14 12.2 0.5 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PQQ_3 PF13570.6 KPA40240.1 - 9.8 6.8 6.4 1e+02 3.6 0.0 4.3 5 0 0 5 5 5 0 PQQ-like domain PT PF04886.12 KPA40241.1 - 0.018 14.6 0.6 10 5.8 0.1 3.0 3 0 0 3 3 3 0 PT repeat Trypan_PARP PF05887.11 KPA40241.1 - 0.72 9.8 25.8 15 5.5 10.5 2.6 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) MscL PF01741.18 KPA40241.1 - 1.3 9.4 6.8 29 5.0 0.3 3.8 2 2 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL eIF2A PF08662.11 KPA40242.1 - 4.7e-36 124.5 3.0 2.6e-34 118.8 0.2 3.8 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KPA40242.1 - 0.0011 18.8 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cofilin_ADF PF00241.20 KPA40242.1 - 0.085 12.7 0.1 37 4.1 0.0 3.6 2 1 1 3 3 3 0 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.32 KPA40242.1 - 0.14 13.1 1.4 5.5 8.0 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat RE_HindIII PF09518.10 KPA40242.1 - 0.18 11.0 0.3 0.3 10.3 0.3 1.2 1 0 0 1 1 1 0 HindIII restriction endonuclease Cpn60_TCP1 PF00118.24 KPA40243.1 - 1.4e-142 475.8 11.1 1.6e-142 475.7 11.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 KPA40243.1 - 0.01 16.0 0.2 0.025 14.7 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 KPA40243.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat RabGAP-TBC PF00566.18 KPA40245.1 - 5.4e-27 94.8 0.0 9.3e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KPA40245.1 - 5.3e-08 31.6 0.6 9.2e-08 30.8 0.6 1.3 1 0 0 1 1 1 1 SBE2, cell-wall formation PAN_1 PF00024.26 KPA40246.1 - 9.1e-05 22.3 10.2 0.013 15.4 4.0 3.0 3 1 0 3 3 3 2 PAN domain adh_short PF00106.25 KPA40247.1 - 2.7e-16 59.6 0.0 8.3e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA40247.1 - 5e-07 29.5 0.0 1e-06 28.5 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA40247.1 - 2.4e-05 24.3 0.1 0.00013 21.9 0.0 1.9 2 0 0 2 2 2 1 KR domain FAD_binding_4 PF01565.23 KPA40248.1 - 9.2e-26 90.2 0.6 1.5e-25 89.6 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Robl_LC7 PF03259.17 KPA40248.1 - 0.19 11.5 1.1 14 5.6 0.0 2.7 3 0 0 3 3 3 0 Roadblock/LC7 domain p450 PF00067.22 KPA40249.1 - 5.4e-63 213.3 0.0 5.7e-24 84.7 0.0 4.7 3 1 0 3 3 3 3 Cytochrome P450 FAD_binding_4 PF01565.23 KPA40250.1 - 1.2e-28 99.6 0.3 2e-28 98.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPA40250.1 - 0.0011 19.0 0.1 0.0038 17.3 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like Dimer_Tnp_hAT PF05699.14 KPA40251.1 - 3.1e-14 52.5 0.1 8.8e-14 51.1 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Sugar_tr PF00083.24 KPA40253.1 - 2.1e-104 349.9 14.0 2.4e-104 349.7 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA40253.1 - 1.3e-20 73.7 24.7 1.3e-20 73.7 24.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KPA40254.1 - 3.7e-24 85.3 5.3 5.1e-19 68.3 1.7 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain RIH_assoc PF08454.11 KPA40254.1 - 0.026 14.4 0.2 0.14 12.0 0.1 2.1 2 0 0 2 2 2 0 RyR and IP3R Homology associated Mpv17_PMP22 PF04117.12 KPA40254.1 - 0.053 13.8 0.3 0.13 12.5 0.3 1.6 1 0 0 1 1 1 0 Mpv17 / PMP22 family FAD_oxidored PF12831.7 KPA40255.1 - 2.4e-102 343.5 0.0 2.7e-102 343.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA40255.1 - 2.4e-06 27.7 0.5 2.9e-05 24.2 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPA40255.1 - 5.2e-06 25.8 1.4 5.4e-05 22.5 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA40255.1 - 0.00026 20.3 0.0 0.0004 19.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA40255.1 - 0.0023 17.6 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KPA40255.1 - 0.0024 17.0 0.5 0.0045 16.1 0.5 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KPA40255.1 - 0.025 13.8 0.5 0.051 12.8 0.5 1.5 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KPA40255.1 - 0.031 13.0 0.1 0.044 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Ank_2 PF12796.7 KPA40256.1 - 4e-45 152.3 13.1 7.6e-09 36.1 0.0 5.2 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA40256.1 - 8.5e-36 121.9 0.2 1.5e-06 28.6 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA40256.1 - 1.9e-23 82.2 4.8 3.1e-06 27.3 0.2 7.8 6 2 2 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA40256.1 - 9.6e-21 71.7 3.0 0.051 14.1 0.0 9.6 10 0 0 10 10 10 6 Ankyrin repeat Ank PF00023.30 KPA40256.1 - 3.4e-17 62.0 13.2 0.023 15.1 0.0 10.0 9 2 1 10 10 10 4 Ankyrin repeat TrkH PF02386.16 KPA40257.1 - 1.3e-116 390.1 5.9 4e-114 381.8 4.6 2.1 2 0 0 2 2 2 2 Cation transport protein SET PF00856.28 KPA40257.1 - 1.4e-12 48.3 0.0 7e-12 46.1 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 KPA40257.1 - 0.00019 21.3 2.8 0.021 14.9 0.6 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KPA40257.1 - 0.017 15.4 1.0 0.048 13.9 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KPA40257.1 - 0.017 15.3 1.4 0.13 12.5 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPA40257.1 - 0.16 11.9 2.5 0.26 11.2 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SieB PF14163.6 KPA40257.1 - 0.31 10.5 1.4 3.1 7.3 0.2 3.1 3 0 0 3 3 3 0 Super-infection exclusion protein B Methyltransf_23 PF13489.6 KPA40258.1 - 4.3e-18 65.7 0.0 6.3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40258.1 - 4.5e-11 43.3 0.0 1.8e-10 41.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA40258.1 - 2.4e-09 37.7 0.0 5.5e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA40258.1 - 1.1e-06 29.3 0.0 4.5e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA40258.1 - 4.9e-06 26.4 0.0 0.009 15.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KPA40258.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KPA40258.1 - 0.0094 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 KPA40258.1 - 0.012 14.9 0.0 0.18 11.1 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KPA40258.1 - 0.033 13.5 0.0 0.11 11.8 0.0 1.9 3 0 0 3 3 3 0 O-methyltransferase domain PrmA PF06325.13 KPA40258.1 - 0.042 13.2 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KPA40258.1 - 0.062 13.1 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 KPA40258.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 KPA40258.1 - 0.1 11.8 0.0 0.61 9.3 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KPA40258.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.6 KPA40259.1 - 3.1e-18 66.1 0.0 4.7e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40259.1 - 5.9e-10 39.7 0.0 3.5e-09 37.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA40259.1 - 1.8e-06 27.8 0.0 0.035 13.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KPA40259.1 - 2.5e-06 28.0 0.0 6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA40259.1 - 6.6e-06 26.8 0.1 8.3e-05 23.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA40259.1 - 0.0011 18.3 0.0 0.026 13.9 0.0 2.8 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KPA40259.1 - 0.0023 18.1 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 KPA40259.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KPA40259.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TRAM_LAG1_CLN8 PF03798.16 KPA40260.1 - 1.8e-44 151.8 20.3 2.7e-44 151.3 20.3 1.3 1 0 0 1 1 1 1 TLC domain ADH_N PF08240.12 KPA40260.1 - 1.2e-24 86.2 0.8 2.4e-24 85.3 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TRAM1 PF08390.11 KPA40260.1 - 3.1e-14 52.3 0.1 1.4e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 TRAM1-like protein ADH_zinc_N PF00107.26 KPA40260.1 - 3.9e-14 52.8 0.0 8.9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPA40260.1 - 0.011 15.1 0.7 0.021 14.2 0.2 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KPA40260.1 - 0.065 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MafB19-deam PF14437.6 KPA40260.1 - 0.15 11.8 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 MafB19-like deaminase HTH_32 PF13565.6 KPA40262.1 - 0.007 17.0 1.7 0.031 14.9 0.0 2.8 3 1 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KPA40262.1 - 0.07 13.3 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Zn_clus PF00172.18 KPA40263.1 - 0.00024 21.2 9.3 0.00057 20.0 9.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_rich_VLP PF14194.6 KPA40263.1 - 0.22 11.6 2.9 0.55 10.4 2.9 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP adh_short PF00106.25 KPA40265.1 - 1e-36 126.3 0.1 1.3e-36 126.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA40265.1 - 5.9e-35 120.9 0.0 9.3e-35 120.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA40265.1 - 1.8e-14 54.0 0.2 2.6e-14 53.5 0.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA40265.1 - 0.00044 19.5 0.0 0.00089 18.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPA40265.1 - 0.0081 15.6 0.0 0.056 12.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KPA40265.1 - 0.014 15.2 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 KPA40265.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 KPA40265.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Metallophos PF00149.28 KPA40266.1 - 1.4e-13 51.8 0.4 3.1e-13 50.7 0.4 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPA40266.1 - 2.8e-05 24.4 0.3 0.022 14.9 0.2 2.4 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Paralemmin PF03285.15 KPA40267.1 - 6 6.3 9.9 0.15 11.6 2.7 2.0 2 0 0 2 2 2 0 Paralemmin PSDC PF12588.8 KPA40268.1 - 7.4e-60 201.0 0.0 1.1e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KPA40268.1 - 1.1e-35 123.0 0.0 1.6e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 KPA40268.1 - 0.00062 19.5 0.6 0.12 12.3 0.3 2.3 2 0 0 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 KPA40268.1 - 0.12 12.4 0.1 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KPA40268.1 - 0.12 12.2 0.2 0.37 10.7 0.2 1.8 2 0 0 2 2 2 0 Biotin-requiring enzyme GST_N PF02798.20 KPA40269.1 - 1.1e-14 54.5 0.0 2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPA40269.1 - 7.8e-13 48.6 0.0 1.3e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPA40269.1 - 4.5e-10 39.6 0.0 8.7e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPA40269.1 - 1.7e-09 37.9 0.0 3.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPA40269.1 - 4.6e-09 36.2 0.0 1.5e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA40269.1 - 5e-09 36.3 0.1 1.3e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF5404 PF17397.2 KPA40269.1 - 0.013 15.7 0.2 0.67 10.1 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5404) GST_C_6 PF17171.4 KPA40269.1 - 0.029 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ank_2 PF12796.7 KPA40270.1 - 2e-20 73.1 4.4 2.9e-08 34.2 0.1 3.9 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA40270.1 - 2.1e-16 60.1 1.2 0.00012 22.6 0.1 4.6 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KPA40270.1 - 9.6e-16 57.4 3.5 1.1e-06 28.8 0.2 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KPA40270.1 - 5.5e-14 52.1 2.7 0.00094 19.4 0.1 5.1 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA40270.1 - 1.6e-12 46.4 3.7 0.00056 20.1 0.1 5.0 4 1 0 4 4 4 3 Ankyrin repeat F_bP_aldolase PF01116.20 KPA40271.1 - 0.00018 21.1 0.3 0.00023 20.7 0.3 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MFS_1 PF07690.16 KPA40272.1 - 2.3e-45 155.0 39.8 5.9e-43 147.1 39.3 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA40272.1 - 2e-20 72.8 23.9 2.8e-20 72.3 23.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPA40272.1 - 3.9e-18 65.6 9.3 3.9e-18 65.6 9.3 2.7 3 1 0 3 3 3 2 Sugar (and other) transporter DUF2868 PF11067.8 KPA40272.1 - 1.6 8.2 7.0 1.7 8.1 5.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) PALP PF00291.25 KPA40273.1 - 1.3e-34 120.0 0.0 2.8e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 KPA40273.1 - 1.4e-07 32.0 0.0 3.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Na_H_Exchanger PF00999.21 KPA40274.1 - 3.6e-24 85.3 32.3 3.5e-23 82.0 25.9 4.3 5 0 0 5 5 5 3 Sodium/hydrogen exchanger family Fst_toxin PF13955.6 KPA40274.1 - 6.4 6.8 6.7 0.58 10.1 0.2 2.7 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system Amidohydro_3 PF07969.11 KPA40275.1 - 1.2e-64 219.6 0.0 2.5e-64 218.5 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.20 KPA40275.1 - 1.9e-11 43.9 0.2 3e-08 33.4 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Fungal_trans_2 PF11951.8 KPA40276.1 - 6.2e-22 77.9 0.1 1.5e-21 76.7 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain CN_hydrolase PF00795.22 KPA40277.1 - 1.1e-32 113.4 0.0 1.5e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LysR_substrate PF03466.20 KPA40277.1 - 0.059 12.7 0.0 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 LysR substrate binding domain AA_permease_2 PF13520.6 KPA40278.1 - 1.4e-56 192.1 51.6 1.8e-56 191.8 51.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA40278.1 - 9.8e-25 87.1 45.7 1.3e-24 86.6 45.7 1.1 1 0 0 1 1 1 1 Amino acid permease DnaJ PF00226.31 KPA40279.1 - 1.5e-20 73.0 1.6 1.5e-20 73.0 1.6 2.0 2 0 0 2 2 2 1 DnaJ domain AIM3 PF17096.5 KPA40279.1 - 0.0029 18.5 9.0 0.0029 18.5 9.0 4.9 4 3 1 5 5 5 1 Altered inheritance of mitochondria protein 3 F-box-like PF12937.7 KPA40280.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 F-box-like Glyco_transf_28 PF03033.20 KPA40282.1 - 9.7e-25 87.2 0.0 2.8e-24 85.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KPA40282.1 - 8.4e-05 21.6 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KPA40282.1 - 0.00022 21.5 0.0 0.013 15.8 0.0 3.1 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain zf-FPG_IleRS PF06827.14 KPA40285.1 - 0.0038 17.0 0.8 0.1 12.5 0.1 2.3 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS Mut7-C PF01927.16 KPA40285.1 - 0.0047 17.0 0.2 0.0052 16.9 0.2 1.1 1 0 0 1 1 1 1 Mut7-C RNAse domain DUF1660 PF07874.11 KPA40285.1 - 0.1 13.1 2.0 4.6 7.8 0.0 2.2 1 1 1 2 2 2 0 Prophage protein (DUF1660) zinc_ribbon_9 PF14369.6 KPA40285.1 - 0.8 10.0 4.3 7.4 6.9 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon DNA_primase_lrg PF04104.14 KPA40286.1 - 1.5e-83 280.3 0.1 1.8e-82 276.7 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic and archaeal DNA primase, large subunit Ank_2 PF12796.7 KPA40287.1 - 0.0014 19.1 0.0 0.0036 17.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA40287.1 - 0.041 14.4 0.2 9.2 7.2 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 KPA40287.1 - 0.16 12.6 0.1 1.1 9.9 0.1 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Clr5 PF14420.6 KPA40288.1 - 1.8e-19 69.7 1.3 1.8e-19 69.7 1.3 1.9 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.6 KPA40288.1 - 2.8e-06 27.5 1.8 8.7e-06 25.9 0.6 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat PRIMA1 PF16101.5 KPA40288.1 - 0.016 15.2 0.8 0.065 13.3 0.2 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 TPR_7 PF13176.6 KPA40288.1 - 0.032 14.3 0.3 0.88 9.8 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KPA40288.1 - 0.052 13.4 1.5 7.2 6.6 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KPA40288.1 - 0.12 12.0 0.5 7.5 6.3 0.0 3.0 3 0 0 3 3 3 0 TPR repeat DUF2375 PF09558.10 KPA40288.1 - 0.14 12.2 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2375) TPR_2 PF07719.17 KPA40288.1 - 0.16 12.2 0.1 1.7 9.0 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KPA40289.1 - 6e-43 147.1 0.0 8.4e-42 143.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40289.1 - 4.4e-27 95.0 0.0 8.1e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPA40289.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KPA40289.1 - 0.029 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KPA40289.1 - 0.17 11.2 0.0 8.5 5.6 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Clr5 PF14420.6 KPA40290.1 - 1.1e-22 80.0 0.2 1.1e-22 80.0 0.2 2.0 2 0 0 2 2 2 1 Clr5 domain GCD14 PF08704.10 KPA40291.1 - 0.0035 17.1 0.0 0.87 9.2 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.6 KPA40291.1 - 0.05 14.6 0.1 0.13 13.3 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KPA40292.1 - 0.0013 19.4 0.0 0.0027 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40292.1 - 0.0019 18.9 0.0 0.0047 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ank_2 PF12796.7 KPA40293.1 - 1.1e-96 317.6 35.3 4.9e-13 49.5 0.1 8.4 1 1 13 14 14 14 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA40293.1 - 9.4e-58 191.9 13.0 1.4e-10 41.4 0.2 10.9 5 4 6 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA40293.1 - 4.7e-45 151.1 21.1 2.8e-07 30.7 0.3 11.7 6 2 5 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA40293.1 - 5.6e-43 140.0 17.8 0.0012 19.1 0.0 15.2 15 0 0 15 15 15 11 Ankyrin repeat Ank PF00023.30 KPA40293.1 - 1.8e-41 138.8 36.0 0.0011 19.3 0.2 15.2 15 0 0 15 15 15 11 Ankyrin repeat Cid2 PF09774.9 KPA40294.1 - 9.3e-54 182.2 0.1 1.1e-53 182.0 0.1 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.8 KPA40295.1 - 5.2e-196 652.5 34.0 8.7e-195 648.5 25.5 2.5 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 KPA40295.1 - 7.5e-22 77.7 27.5 5e-05 23.9 3.1 10.6 9 3 3 12 12 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 KPA40295.1 - 6e-19 68.3 29.6 0.00085 19.8 0.4 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KPA40295.1 - 2.5e-17 61.5 38.1 0.00054 19.9 0.1 12.0 12 1 0 12 12 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 KPA40295.1 - 2.5e-16 58.9 24.1 0.0018 18.9 0.1 11.7 7 4 5 12 12 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA40295.1 - 1e-13 51.3 21.1 0.0017 18.6 0.5 5.4 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KPA40295.1 - 1.9e-11 43.4 18.4 4.2e-05 23.1 0.2 7.8 8 0 0 8 8 7 3 TPR repeat TPR_9 PF13371.6 KPA40295.1 - 2.1e-11 43.8 8.0 0.00034 20.7 1.7 6.9 6 2 1 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KPA40295.1 - 2.1e-10 39.9 31.7 0.00013 21.7 0.1 9.8 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPA40295.1 - 3e-09 37.0 26.3 0.093 13.0 3.2 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KPA40295.1 - 4.8e-06 26.6 9.5 4.7 7.8 0.0 8.8 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 KPA40295.1 - 9.6e-06 25.8 5.8 0.61 10.9 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA40295.1 - 3.6e-05 23.6 26.3 0.0073 16.4 0.0 9.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 KPA40295.1 - 0.00043 19.6 23.3 0.0026 17.0 1.9 4.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KPA40295.1 - 0.032 14.9 27.2 7 7.5 0.1 9.3 10 0 0 10 10 7 0 Tetratricopeptide repeat BTAD PF03704.17 KPA40295.1 - 0.12 12.9 17.2 0.18 12.2 0.7 4.1 3 1 1 4 4 3 0 Bacterial transcriptional activator domain TPR_7 PF13176.6 KPA40295.1 - 0.15 12.2 16.6 65 3.9 0.0 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 KPA40295.1 - 0.21 11.5 14.0 5.2 7.1 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat PTPRCAP PF15713.5 KPA40295.1 - 1.2 9.4 7.3 3.8 7.8 7.3 1.8 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Wzy_C_2 PF11846.8 KPA40295.1 - 4.8 7.1 7.3 0.66 9.9 0.3 3.2 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal DAGK_cat PF00781.24 KPA40296.1 - 1.4e-26 92.5 0.0 2.5e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain BTB PF00651.31 KPA40297.1 - 0.00072 19.8 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Pap_E4 PF02711.14 KPA40297.1 - 0.53 11.3 4.8 0.93 10.5 1.0 2.6 2 0 0 2 2 2 0 E4 protein SET PF00856.28 KPA40300.1 - 3e-18 66.8 0.0 1e-17 65.0 0.0 1.8 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 KPA40300.1 - 2.2e-07 31.5 3.0 7.4e-07 29.8 1.2 2.1 2 0 0 2 2 2 1 Pre-SET motif UBD PF16455.5 KPA40301.1 - 2.8e-38 130.4 0.1 4.4e-38 129.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KPA40301.1 - 1.6e-06 27.8 0.0 2.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 KPA40301.1 - 0.0013 18.8 0.1 0.0032 17.6 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KPA40301.1 - 0.0016 19.0 0.2 0.0039 17.7 0.2 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 KPA40301.1 - 0.019 14.8 0.8 0.031 14.1 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Adaptin_N PF01602.20 KPA40302.1 - 1.1e-90 304.7 7.3 1.9e-90 303.9 7.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KPA40302.1 - 3.1e-59 198.9 0.3 6.5e-59 197.8 0.3 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KPA40302.1 - 1.9e-56 189.5 0.0 5.3e-56 188.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KPA40302.1 - 1.8e-10 41.1 2.1 7.7e-07 29.3 0.0 3.0 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KPA40302.1 - 1.7e-05 25.1 2.8 0.022 15.1 0.0 4.6 3 2 1 4 4 4 1 HEAT repeats Coatomer_g_Cpla PF16381.5 KPA40302.1 - 5.5e-05 23.3 0.0 0.00079 19.5 0.0 2.6 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform AP4E_app_platf PF14807.6 KPA40302.1 - 0.03 14.7 0.2 0.11 12.9 0.2 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT PF02985.22 KPA40302.1 - 0.051 13.9 0.1 28 5.3 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat Mago_nashi PF02792.14 KPA40303.1 - 3.9e-72 241.0 0.2 4.3e-72 240.8 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.9 KPA40304.1 - 8.1e-70 233.8 1.9 1e-69 233.5 1.9 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein UPF0020 PF01170.18 KPA40305.1 - 8.9e-09 35.3 0.0 3.4e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 SQS_PSY PF00494.19 KPA40305.1 - 0.075 12.5 0.0 0.6 9.5 0.0 2.0 2 0 0 2 2 2 0 Squalene/phytoene synthase Ribonuc_P_40 PF08584.11 KPA40306.1 - 2.9e-52 177.7 0.0 4.8e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Ank_5 PF13857.6 KPA40307.1 - 4.3e-10 39.6 0.1 8.2e-09 35.6 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA40307.1 - 1.3e-05 25.7 0.3 4.7e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA40307.1 - 4.3e-05 24.0 0.0 0.00015 22.2 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA40307.1 - 0.00021 21.5 0.4 0.01 16.3 0.2 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KPA40307.1 - 0.13 12.8 0.2 0.57 10.7 0.2 2.1 2 0 0 2 2 2 0 Ankyrin repeat tRNA_lig_CPD PF08302.11 KPA40308.1 - 2.7e-91 305.5 0.0 4.5e-91 304.8 0.0 1.4 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KPA40308.1 - 5e-86 288.1 0.0 1e-85 287.1 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KPA40308.1 - 3.2e-53 180.3 0.1 7e-53 179.1 0.1 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 KPA40308.1 - 0.1 13.1 0.1 2.8 8.5 0.1 3.1 3 1 0 3 3 3 0 AAA domain Ribosomal_L10 PF00466.20 KPA40310.1 - 0.00065 19.8 0.1 0.0077 16.3 0.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L10 AAA PF00004.29 KPA40311.1 - 9.8e-40 136.0 0.0 1.9e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KPA40311.1 - 1.5e-18 66.4 0.1 3.1e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KPA40311.1 - 4.4e-08 32.8 0.0 9.8e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KPA40311.1 - 0.00012 22.5 1.7 0.02 15.3 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KPA40311.1 - 0.00015 21.8 0.1 0.00071 19.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KPA40311.1 - 0.00038 20.2 0.0 0.0009 19.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KPA40311.1 - 0.0014 19.0 1.6 0.082 13.2 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 KPA40311.1 - 0.0015 18.6 0.0 0.011 15.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 KPA40311.1 - 0.006 16.1 0.2 0.08 12.4 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KPA40311.1 - 0.0084 15.5 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KPA40311.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KPA40311.1 - 0.014 15.5 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KPA40311.1 - 0.074 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KPA40311.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KPA40311.1 - 0.59 9.9 0.0 0.59 9.9 0.0 2.6 2 1 1 3 3 3 0 AAA domain DUF4065 PF13274.6 KPA40311.1 - 1.4 9.9 3.3 3.2 8.7 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) RPN2_C PF18004.1 KPA40311.1 - 1.7 8.5 5.7 3.6 7.5 5.7 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ish1 PF10281.9 KPA40312.1 - 1.8e-87 287.3 24.6 2.9e-14 53.1 0.0 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KPA40312.1 - 1.7e-09 37.2 0.0 7.2 6.5 0.0 6.9 7 1 0 7 7 7 4 SAP domain Slx4 PF09494.10 KPA40312.1 - 2.4e-08 33.8 0.9 1.4 8.9 0.0 6.5 8 1 0 8 8 8 2 Slx4 endonuclease HeH PF12949.7 KPA40312.1 - 2.5e-08 33.5 0.0 0.065 12.9 0.0 5.3 6 0 0 6 6 6 2 HeH/LEM domain Thymopoietin PF08198.11 KPA40312.1 - 0.029 14.0 0.0 1.3 8.7 0.0 3.5 4 0 0 4 4 4 0 Thymopoietin protein Endonuc-dimeris PF09124.10 KPA40312.1 - 0.032 14.4 0.0 15 5.9 0.0 3.8 4 0 0 4 4 4 0 T4 recombination endonuclease VII, dimerisation BOP1NT PF08145.12 KPA40313.1 - 5.6e-105 350.9 8.1 7.7e-105 350.5 8.1 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KPA40313.1 - 2.6e-26 91.4 0.8 3.6e-11 43.4 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA40313.1 - 1.7e-06 28.2 0.0 0.0033 17.7 0.0 4.6 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KPA40313.1 - 0.012 14.0 0.0 0.1 10.9 0.0 2.1 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KPA40313.1 - 0.035 13.1 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein COesterase PF00135.28 KPA40314.1 - 1.9e-91 307.5 0.3 2.3e-91 307.2 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA40314.1 - 2.8e-05 24.1 0.1 0.00012 22.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Nrap_D6 PF17407.2 KPA40314.1 - 0.17 12.1 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Nrap protein domain 6 RSN1_7TM PF02714.15 KPA40315.1 - 2.6e-79 266.4 19.1 4.9e-79 265.5 19.1 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KPA40315.1 - 2.5e-40 138.6 0.0 3.6e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KPA40315.1 - 2.3e-34 118.4 2.6 2.3e-34 118.4 2.6 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Glycos_transf_2 PF00535.26 KPA40317.1 - 3.2e-37 128.0 0.0 3.7e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KPA40317.1 - 8.4e-13 48.7 0.0 1.1e-12 48.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KPA40317.1 - 2.7e-06 27.0 0.0 4.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KPA40317.1 - 0.0002 21.0 0.0 0.00026 20.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 adh_short_C2 PF13561.6 KPA40318.1 - 1.2e-48 165.7 3.3 7.1e-46 156.7 3.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA40318.1 - 8.9e-44 149.3 0.7 1.1e-43 148.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA40318.1 - 2.3e-15 57.0 0.1 3.5e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KPA40318.1 - 0.01 15.7 0.3 0.014 15.3 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KPA40318.1 - 0.037 14.3 0.1 0.058 13.7 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AdoHcyase_NAD PF00670.21 KPA40318.1 - 0.075 13.1 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ANAPC3 PF12895.7 KPA40319.1 - 5.4e-06 26.5 0.1 2.2e-05 24.6 0.0 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KPA40319.1 - 0.00015 21.6 0.0 0.84 9.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KPA40319.1 - 0.002 18.6 3.9 0.8 10.3 0.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPA40319.1 - 0.012 16.2 5.4 1.6 9.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KPA40319.1 - 0.016 14.6 0.7 0.039 13.4 0.5 1.7 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_14 PF13428.6 KPA40319.1 - 0.028 15.2 3.0 3.1 8.9 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPA40319.1 - 0.03 14.9 0.6 5.6 7.9 0.1 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat HemY_N PF07219.13 KPA40319.1 - 0.21 11.8 1.3 0.45 10.7 0.1 2.1 2 0 0 2 2 2 0 HemY protein N-terminus BTB PF00651.31 KPA40320.1 - 0.027 14.7 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 KPA40321.1 - 6.6e-06 26.3 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KPA40322.1 - 0.0057 16.9 0.0 0.0098 16.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain ANAPC4_WD40 PF12894.7 KPA40323.1 - 0.00049 20.3 0.0 0.7 10.2 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain HlyIII PF03006.20 KPA40324.1 - 9.3e-51 172.7 12.4 1.2e-50 172.3 12.4 1.0 1 0 0 1 1 1 1 Haemolysin-III related Bax1-I PF01027.20 KPA40324.1 - 0.057 13.2 13.4 0.09 12.6 13.4 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF962 PF06127.11 KPA40324.1 - 0.34 11.0 2.3 1.1 9.4 2.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF962) TMA7 PF09072.10 KPA40325.1 - 2.4e-25 89.1 18.4 2.7e-25 89.0 18.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.25 KPA40326.1 - 5.1e-53 180.1 0.0 7.3e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40326.1 - 1e-23 84.0 0.0 2.6e-23 82.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KPA40326.1 - 0.023 13.7 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KPA40326.1 - 0.037 13.6 0.0 0.095 12.3 0.0 1.6 1 0 0 1 1 1 0 RIO1 family FixS PF03597.15 KPA40326.1 - 0.11 12.2 1.9 0.33 10.7 0.1 2.4 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Trypan_PARP PF05887.11 KPA40326.1 - 8.1 6.4 18.5 0.017 15.1 6.1 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 KPA40327.1 - 4e-54 183.8 0.0 5.3e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40327.1 - 3.5e-30 105.1 0.0 4.5e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA40327.1 - 0.00021 20.7 0.0 0.0067 15.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KPA40327.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KPA40327.1 - 0.003 16.9 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KPA40327.1 - 0.01 15.5 0.0 0.055 13.1 0.0 1.9 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KPA40327.1 - 0.022 13.6 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KPA40327.1 - 0.043 12.7 0.0 0.092 11.7 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KPA40327.1 - 0.2 10.6 0.1 0.31 10.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AA_permease PF00324.21 KPA40328.1 - 8.9e-110 367.5 41.0 1.1e-109 367.3 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA40328.1 - 1.2e-29 103.4 41.6 1.6e-29 103.0 41.6 1.0 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_1 PF00561.20 KPA40329.1 - 2.6e-11 43.7 2.0 8e-10 38.8 2.0 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KPA40329.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DUF4448 PF14610.6 KPA40330.1 - 0.055 13.3 0.0 0.084 12.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 KPA40330.1 - 0.067 12.6 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 KPA40330.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 KPA40330.1 - 0.26 10.1 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein TrkH PF02386.16 KPA40331.1 - 2.5e-113 379.2 1.1 3.8e-111 372.0 0.3 2.1 2 0 0 2 2 2 2 Cation transport protein CAP59_mtransfer PF11735.8 KPA40333.1 - 3.5e-67 226.6 0.0 4.7e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 VSP PF03302.13 KPA40334.1 - 0.0099 14.8 0.1 0.017 14.0 0.1 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 KPA40334.1 - 0.037 13.4 1.6 0.11 12.0 1.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4083 PF13314.6 KPA40334.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) PTP_tm PF18861.1 KPA40334.1 - 0.072 13.1 0.8 0.18 11.8 0.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF202 PF02656.15 KPA40334.1 - 0.093 13.2 0.1 0.29 11.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF2613 PF11021.8 KPA40334.1 - 0.097 12.8 3.9 0.092 12.9 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) FtsA PF14450.6 KPA40335.1 - 0.12 12.9 0.0 2.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Cell division protein FtsA HSP70 PF00012.20 KPA40335.1 - 0.16 10.1 0.6 12 4.0 0.0 2.6 3 0 0 3 3 3 0 Hsp70 protein EutA PF06277.11 KPA40335.1 - 0.18 10.6 0.5 11 4.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA Glyco_hydro_47 PF01532.20 KPA40336.1 - 3.6e-175 583.3 0.0 7.8e-175 582.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 Cpn60_TCP1 PF00118.24 KPA40337.1 - 7.8e-153 509.6 7.0 8.9e-153 509.4 7.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 KPA40337.1 - 0.13 12.7 0.1 0.6 10.6 0.0 2.1 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch FtsA PF14450.6 KPA40337.1 - 0.22 11.9 2.0 0.64 10.5 2.1 2.0 1 1 0 1 1 1 0 Cell division protein FtsA zf-H2C2 PF09337.10 KPA40338.1 - 3.6e-16 59.1 1.6 6.4e-16 58.3 1.6 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KPA40338.1 - 1.8e-11 43.9 0.3 3.8e-11 42.9 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KPA40338.1 - 2.2e-05 24.7 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KPA40338.1 - 0.0018 18.4 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KPA40338.1 - 0.0059 17.3 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA40338.1 - 0.17 11.9 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Ribosomal_S2 PF00318.20 KPA40339.1 - 3.8e-61 206.1 1.0 6.2e-60 202.1 0.1 2.7 2 1 0 2 2 2 1 Ribosomal protein S2 DUF2802 PF10975.8 KPA40339.1 - 0.17 12.1 2.3 56 4.0 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) DUF4140 PF13600.6 KPA40339.1 - 0.19 12.2 15.1 3.1 8.3 1.5 3.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Sec2p PF06428.11 KPA40339.1 - 0.26 11.3 12.1 1.5 8.9 0.1 4.3 5 0 0 5 5 5 0 GDP/GTP exchange factor Sec2p CHDCT2 PF08074.11 KPA40339.1 - 5 7.3 5.5 11 6.2 0.5 2.8 1 1 2 3 3 3 0 CHDCT2 (NUC038) domain CBS PF00571.28 KPA40340.1 - 3.6e-34 117.0 6.8 1.1e-08 35.4 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KPA40340.1 - 3.4e-05 23.7 0.3 8.7e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 PB1 domain PikAIV_N PF18605.1 KPA40340.1 - 0.095 12.3 0.3 6.7 6.4 0.2 2.5 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Exo70 PF03081.15 KPA40340.1 - 0.2 10.6 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 Exo70 exocyst complex subunit zf-C2H2 PF00096.26 KPA40342.1 - 1.4e-10 41.0 18.0 0.00017 21.8 5.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPA40342.1 - 1.6e-07 31.5 11.7 0.0032 17.8 2.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPA40342.1 - 2.8e-05 24.6 16.5 0.09 13.7 4.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KPA40342.1 - 0.0017 18.1 6.7 0.025 14.3 1.3 2.7 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KPA40342.1 - 0.31 11.1 6.5 8.7 6.5 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-MYND PF01753.18 KPA40343.1 - 1.5e-11 44.2 15.8 3.5e-11 43.0 15.8 1.7 1 0 0 1 1 1 1 MYND finger DUF4470 PF14737.6 KPA40343.1 - 4.9e-10 39.5 0.4 1.1e-07 31.9 0.4 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) zf-C6H2 PF15801.5 KPA40343.1 - 1.5 9.2 11.3 3.5 8.0 11.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Cpn60_TCP1 PF00118.24 KPA40344.1 - 6.9e-162 539.5 1.9 8.2e-162 539.2 1.9 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDCD2_C PF04194.13 KPA40344.1 - 5.7e-43 147.0 0.0 1.5e-42 145.7 0.0 1.7 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Herpes_UL6 PF01763.16 KPA40344.1 - 0.2 10.1 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Pol_alpha_B_N PF08418.10 KPA40344.1 - 0.76 9.7 5.3 1.6 8.6 5.3 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CSN8_PSD8_EIF3K PF10075.9 KPA40345.1 - 6.4e-33 113.8 0.0 8.7e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DNA_ligase_A_M PF01068.21 KPA40346.1 - 3.2e-51 173.9 0.1 1.1e-48 165.6 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KPA40346.1 - 8.2e-36 123.9 0.0 2e-35 122.7 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KPA40346.1 - 1.9e-19 70.1 0.0 7.3e-19 68.2 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KPA40346.1 - 0.00014 22.2 0.0 0.00044 20.6 0.0 1.8 2 0 0 2 2 2 1 RNA ligase mRNA_cap_enzyme PF01331.19 KPA40346.1 - 0.014 15.2 0.1 4 7.2 0.0 2.6 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain FAM195 PF14799.6 KPA40346.1 - 0.76 10.1 3.3 0.88 9.9 1.5 2.0 2 0 0 2 2 2 0 FAM195 family Adaptin_N PF01602.20 KPA40347.1 - 2.1e-138 462.2 4.9 2.7e-138 461.8 4.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KPA40347.1 - 4.5e-65 218.6 2.6 1.7e-61 207.0 0.2 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KPA40347.1 - 1.7e-17 63.5 0.3 7.2e-08 32.7 0.0 5.6 1 1 6 7 7 7 4 HEAT repeats HEAT PF02985.22 KPA40347.1 - 1e-09 37.8 6.9 0.023 14.9 0.0 6.4 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 KPA40347.1 - 8.8e-05 22.9 1.1 0.64 10.6 0.0 4.9 4 1 1 5 5 5 1 HEAT-like repeat Arm PF00514.23 KPA40347.1 - 0.00013 21.9 0.6 0.023 14.7 0.0 4.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 KPA40347.1 - 0.0024 17.9 0.4 0.28 11.1 0.1 2.9 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KPA40347.1 - 0.041 13.4 0.1 1.7 8.2 0.0 3.2 2 1 1 3 3 3 0 CLASP N terminal Atx10homo_assoc PF09759.9 KPA40347.1 - 0.077 13.0 0.0 26 4.9 0.0 3.6 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain LuxT_C PF18285.1 KPA40347.1 - 0.079 13.5 0.1 0.25 11.9 0.1 1.9 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain BolA PF01722.18 KPA40348.1 - 1.3e-20 73.4 0.1 3.6e-20 72.0 0.1 1.7 1 1 0 1 1 1 1 BolA-like protein NIF3 PF01784.18 KPA40349.1 - 3.7e-64 216.7 0.0 4.4e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Vps51 PF08700.11 KPA40350.1 - 7.8e-29 99.6 1.0 1.3e-28 98.9 0.2 1.7 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 KPA40350.1 - 9.3e-06 24.5 0.1 1.2e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family BBP1_C PF15272.6 KPA40350.1 - 0.041 13.7 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal COG5 PF10392.9 KPA40350.1 - 0.059 13.6 0.2 0.14 12.3 0.2 1.7 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Vps53_N PF04100.12 KPA40350.1 - 0.082 11.9 0.2 0.11 11.4 0.2 1.3 1 0 0 1 1 1 0 Vps53-like, N-terminal ATG16 PF08614.11 KPA40350.1 - 0.32 11.2 4.0 0.38 10.9 1.0 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) RMI1_N PF08585.12 KPA40351.1 - 3.1e-58 197.1 0.0 3.5e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_16 PF13432.6 KPA40352.1 - 9.4e-31 106.2 40.4 0.00012 22.6 0.2 13.2 11 3 3 14 14 13 7 Tetratricopeptide repeat TPR_1 PF00515.28 KPA40352.1 - 1.2e-30 104.0 17.3 1.7e-05 24.4 0.0 14.1 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 KPA40352.1 - 2e-29 99.3 42.3 0.0007 19.5 0.1 16.8 17 0 0 17 17 17 7 Tetratricopeptide repeat TPR_19 PF14559.6 KPA40352.1 - 5.4e-28 97.3 21.7 6.9e-06 26.5 0.1 10.3 8 3 2 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 KPA40352.1 - 2.4e-26 89.7 19.4 0.0059 16.7 0.1 14.0 14 0 0 14 14 12 5 Tetratricopeptide repeat TPR_14 PF13428.6 KPA40352.1 - 7.7e-24 82.4 35.6 0.0012 19.5 0.0 15.2 13 4 4 17 17 14 5 Tetratricopeptide repeat TPR_12 PF13424.6 KPA40352.1 - 5e-21 74.8 39.3 3.8e-05 23.9 0.3 12.7 12 1 0 12 12 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 KPA40352.1 - 1.2e-18 66.1 15.8 1.9 9.1 0.0 15.5 16 1 1 17 17 15 2 Tetratricopeptide repeat TPR_11 PF13414.6 KPA40352.1 - 2.7e-18 65.3 18.9 0.0012 18.5 0.1 10.2 11 1 1 12 12 12 4 TPR repeat TPR_7 PF13176.6 KPA40352.1 - 1.7e-13 49.6 29.3 0.0015 18.4 0.2 12.3 15 2 1 16 16 15 4 Tetratricopeptide repeat TPR_6 PF13174.6 KPA40352.1 - 3.8e-08 33.5 33.2 0.047 14.3 0.0 13.9 16 0 0 16 16 13 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA40352.1 - 7.4e-08 32.5 17.8 0.12 12.6 0.1 7.9 5 3 4 9 9 9 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_22 PF18833.1 KPA40352.1 - 1.2e-07 31.7 0.5 6.4e-07 29.4 0.0 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KPA40352.1 - 2.1e-07 31.0 9.3 0.49 10.6 0.3 6.8 5 2 1 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KPA40352.1 - 1.6e-05 24.6 17.7 0.13 12.1 0.0 8.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 KPA40352.1 - 0.0053 17.3 21.6 0.24 12.2 0.1 9.5 11 0 0 11 11 8 1 Tetratricopeptide repeat ChAPs PF09295.10 KPA40352.1 - 0.0076 15.3 2.1 14 4.6 0.4 4.3 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) HemY_N PF07219.13 KPA40352.1 - 0.016 15.4 11.8 3.4 7.9 0.1 5.7 4 1 1 5 5 4 0 HemY protein N-terminus HrpB1_HrpK PF09613.10 KPA40352.1 - 0.02 14.5 4.4 2.3 7.9 0.1 4.1 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.6 KPA40352.1 - 0.057 13.5 9.3 29 4.9 0.2 6.9 7 1 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat DUF4192 PF13830.6 KPA40352.1 - 0.1 12.7 17.6 0.3 11.1 1.7 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF4192) RPN6_N PF18055.1 KPA40352.1 - 0.13 12.6 0.1 0.13 12.6 0.1 5.1 6 0 0 6 6 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain Zn_clus PF00172.18 KPA40355.1 - 3.8e-10 39.7 6.7 7.3e-10 38.8 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA40355.1 - 0.00056 18.8 0.0 0.00078 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_5_C PF18564.1 KPA40356.1 - 1.5e-21 76.7 0.0 3.8e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KPA40356.1 - 2.9e-12 46.6 0.3 7.4e-09 35.4 0.1 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.19 KPA40356.1 - 0.0016 18.1 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KPA40356.1 - 0.0073 15.7 0.5 0.53 9.6 0.0 2.2 2 0 0 2 2 2 2 Beta-galactosidase Pectinesterase PF01095.19 KPA40359.1 - 1.8e-26 92.5 0.0 2.7e-24 85.4 0.2 2.1 2 0 0 2 2 2 2 Pectinesterase Pectate_lyase_3 PF12708.7 KPA40359.1 - 0.0007 19.5 3.0 0.0012 18.7 3.0 1.4 1 0 0 1 1 1 1 Pectate lyase superfamily protein Cu_bind_like PF02298.17 KPA40360.1 - 0.00099 19.1 0.1 0.0026 17.7 0.1 1.6 1 1 0 1 1 1 1 Plastocyanin-like domain APH PF01636.23 KPA40361.1 - 3.8e-17 63.0 0.0 4.9e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KPA40361.1 - 0.013 14.4 0.1 0.1 11.4 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) RIO1 PF01163.22 KPA40361.1 - 0.085 12.4 0.0 0.81 9.2 0.0 2.2 2 0 0 2 2 2 0 RIO1 family UTP25 PF06862.12 KPA40361.1 - 0.17 10.7 0.1 0.24 10.2 0.1 1.1 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AhpC-TSA PF00578.21 KPA40362.1 - 6.4e-30 103.6 0.0 8.4e-30 103.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPA40362.1 - 2.7e-13 49.9 0.0 3.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KPA40362.1 - 3.3e-10 39.7 0.0 6.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_3 PF13415.6 KPA40364.1 - 2e-15 56.6 6.1 4.2e-09 36.5 0.0 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 KPA40364.1 - 2.3e-15 56.3 0.3 0.00013 21.9 0.0 5.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KPA40364.1 - 1.8e-13 49.8 0.0 0.0014 18.2 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KPA40364.1 - 3.8e-12 46.0 4.7 0.00092 19.4 0.4 4.9 3 1 1 4 4 4 3 Kelch motif Kelch_5 PF13854.6 KPA40364.1 - 4.4e-11 42.5 7.0 1.8e-05 24.6 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KPA40364.1 - 5.3e-07 29.4 4.1 0.00037 20.4 0.0 5.0 5 1 0 5 5 5 1 Kelch motif BTB PF00651.31 KPA40364.1 - 0.048 13.9 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain AMP-binding PF00501.28 KPA40365.1 - 5.3e-68 229.5 0.0 1.4e-67 228.2 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA40365.1 - 9e-08 33.0 0.1 2.3e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PIG-S PF10510.9 KPA40366.1 - 3.3e-168 560.7 0.1 3.8e-168 560.5 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Peptidase_S15 PF02129.18 KPA40367.1 - 0.00046 19.9 0.0 0.00076 19.1 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KPA40367.1 - 0.026 14.0 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Alpha-L-AF_C PF06964.12 KPA40368.1 - 2.9e-31 108.9 0.0 4.5e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 KPA40368.1 - 0.022 14.7 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Glycoside hydrolase family 44 Sugar_tr PF00083.24 KPA40369.1 - 6.6e-98 328.5 15.5 7.5e-98 328.3 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA40369.1 - 2.2e-30 105.8 26.8 1.8e-24 86.4 4.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA40369.1 - 7e-05 21.6 16.7 0.0034 16.0 0.2 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein BCS1_N PF08740.11 KPA40370.1 - 4.3e-30 105.1 2.4 1.8e-28 99.8 0.1 3.1 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KPA40370.1 - 2e-17 63.9 0.0 6.2e-09 36.4 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPA40370.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPA40370.1 - 0.016 15.6 0.0 0.04 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KPA40370.1 - 0.017 15.1 0.0 0.059 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KPA40370.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 KPA40370.1 - 0.031 14.1 0.7 0.56 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KPA40370.1 - 0.043 13.0 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 KPA40370.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Polyoma_lg_T_C PF06431.11 KPA40370.1 - 0.66 8.8 0.0 0.66 8.8 0.0 1.8 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus RXT2_N PF08595.11 KPA40370.1 - 0.69 9.9 10.3 0.44 10.6 6.4 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal AAA_18 PF13238.6 KPA40370.1 - 1.8 9.1 4.2 1.1 9.9 0.1 2.5 2 1 0 2 2 2 0 AAA domain Iwr1 PF08574.10 KPA40370.1 - 5.3 8.1 13.3 2.2 9.4 9.7 2.1 2 0 0 2 2 2 0 Transcription factor Iwr1 DUF4515 PF14988.6 KPA40371.1 - 3 7.6 12.9 53 3.6 12.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) Syntaxin-6_N PF09177.11 KPA40371.1 - 8.2 7.0 8.0 13 6.4 2.1 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Myb_DNA-binding PF00249.31 KPA40372.1 - 2.6e-08 33.9 0.1 1.7e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPA40372.1 - 9.8e-05 22.5 0.1 0.00039 20.6 0.0 2.0 1 1 1 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 KPA40372.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UbiA PF01040.18 KPA40373.1 - 4.7e-60 203.0 13.7 4.7e-60 203.0 13.7 1.8 1 1 1 2 2 2 1 UbiA prenyltransferase family TetR_C_11 PF16859.5 KPA40373.1 - 0.13 12.6 2.2 0.34 11.2 2.2 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TAL_FSA PF00923.19 KPA40374.1 - 8e-51 173.1 0.0 9.1e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase MutS_V PF00488.21 KPA40376.1 - 6.7e-66 221.9 0.2 1.2e-65 221.1 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KPA40376.1 - 4e-42 144.6 0.4 1.1e-41 143.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KPA40376.1 - 2.3e-32 111.6 0.2 5.6e-32 110.3 0.2 1.7 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 KPA40376.1 - 6.1e-16 58.5 1.5 1.5e-15 57.3 1.5 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KPA40376.1 - 6.7e-14 52.3 0.1 4.1e-13 49.8 0.0 2.4 2 0 0 2 2 2 1 MutS domain II AAA_27 PF13514.6 KPA40376.1 - 0.058 13.0 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KPA40376.1 - 0.086 13.3 0.0 0.086 13.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KPA40376.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KPA40376.1 - 0.21 11.3 0.5 0.5 10.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KPA40376.1 - 0.67 9.7 5.0 0.14 12.0 0.2 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MFS_1 PF07690.16 KPA40377.1 - 4.2e-28 98.3 65.9 1.2e-26 93.5 66.4 2.9 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF1772 PF08592.11 KPA40377.1 - 0.27 11.6 0.1 0.27 11.6 0.1 4.7 1 1 2 4 4 4 0 Domain of unknown function (DUF1772) DUF5353 PF17304.2 KPA40377.1 - 3.7 7.3 5.7 5.4 6.8 0.4 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5353) AAA_2 PF07724.14 KPA40378.1 - 9.3e-45 152.8 0.0 9.3e-45 152.8 0.0 3.2 4 1 0 4 4 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KPA40378.1 - 2.2e-31 107.9 4.0 2.2e-31 107.9 4.0 4.0 4 0 0 4 4 3 1 AAA lid domain AAA PF00004.29 KPA40378.1 - 6.3e-27 94.6 0.0 3.4e-14 53.4 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KPA40378.1 - 2.5e-23 81.9 2.9 4.8e-23 81.0 0.6 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KPA40378.1 - 3.8e-15 56.1 0.1 1e-09 38.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPA40378.1 - 1.1e-12 48.5 0.9 8.5e-05 22.8 0.0 4.3 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KPA40378.1 - 2.5e-10 41.0 14.3 3.6e-06 27.5 0.1 5.4 4 3 1 6 6 5 2 AAA ATPase domain Sigma54_activat PF00158.26 KPA40378.1 - 4.8e-09 36.2 0.0 3.9e-06 26.7 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 KPA40378.1 - 1.8e-06 28.5 0.5 0.12 12.9 0.0 4.1 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 KPA40378.1 - 2.2e-06 27.3 0.0 0.0095 15.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 KPA40378.1 - 3.1e-06 27.8 4.9 0.35 11.3 0.0 3.9 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KPA40378.1 - 3.6e-06 26.8 0.0 0.065 13.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KPA40378.1 - 6e-06 26.3 0.0 0.23 11.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain Clp_N PF02861.20 KPA40378.1 - 6e-06 26.3 3.6 0.0028 17.8 0.0 3.8 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component ATPase_2 PF01637.18 KPA40378.1 - 6.1e-06 26.3 5.2 0.013 15.5 0.1 4.8 4 1 1 5 5 5 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KPA40378.1 - 1.1e-05 25.6 0.1 0.25 11.5 0.0 3.4 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KPA40378.1 - 1.2e-05 24.7 0.1 0.2 11.0 0.1 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KPA40378.1 - 2.5e-05 24.6 0.1 0.41 10.9 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KPA40378.1 - 4.5e-05 23.8 2.4 0.062 13.6 0.1 4.2 5 1 0 5 5 3 1 AAA domain AAA_30 PF13604.6 KPA40378.1 - 7.4e-05 22.5 0.0 0.92 9.2 0.0 3.3 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KPA40378.1 - 7.8e-05 23.0 0.0 0.49 10.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_3 PF07726.11 KPA40378.1 - 9.3e-05 22.3 0.1 0.96 9.3 0.0 4.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KPA40378.1 - 0.00015 21.7 0.0 0.14 12.0 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KPA40378.1 - 0.00018 21.3 0.0 0.33 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KPA40378.1 - 0.00019 22.0 0.3 0.7 10.4 0.0 3.4 3 0 0 3 3 3 1 ABC transporter TsaE PF02367.17 KPA40378.1 - 0.00037 20.5 0.0 0.48 10.4 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KPA40378.1 - 0.00059 19.0 0.9 0.0098 15.0 0.4 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein RuvB_N PF05496.12 KPA40378.1 - 0.00064 19.5 1.8 4.5 7.0 0.8 4.3 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KPA40378.1 - 0.0014 18.0 0.1 0.42 9.9 0.0 3.0 4 0 0 4 4 2 1 Zeta toxin AAA_29 PF13555.6 KPA40378.1 - 0.0031 17.2 0.0 3.2 7.5 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 KPA40378.1 - 0.0031 17.4 0.0 0.33 10.9 0.0 3.6 3 0 0 3 3 3 1 NTPase NACHT PF05729.12 KPA40378.1 - 0.0036 17.2 0.0 0.71 9.8 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Roc PF08477.13 KPA40378.1 - 0.0038 17.4 0.0 2 8.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KPA40378.1 - 0.0042 17.0 0.4 7.1 6.5 0.0 3.5 3 0 0 3 3 3 0 Rad17 P-loop domain SRP54 PF00448.22 KPA40378.1 - 0.01 15.5 0.0 3.6 7.1 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain ResIII PF04851.15 KPA40378.1 - 0.025 14.6 0.0 2 8.4 0.0 3.2 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Torsin PF06309.11 KPA40378.1 - 0.029 14.5 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 Torsin AAA_15 PF13175.6 KPA40378.1 - 0.048 13.4 2.6 12 5.5 0.5 3.6 4 0 0 4 4 3 0 AAA ATPase domain CbiA PF01656.23 KPA40378.1 - 0.059 13.4 0.3 48 4.0 0.0 3.9 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_21 PF13304.6 KPA40378.1 - 0.093 12.5 0.8 24 4.6 0.0 3.5 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system V_ATPase_I PF01496.19 KPA40378.1 - 0.11 10.4 3.5 0.22 9.4 3.5 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATP_bind_1 PF03029.17 KPA40378.1 - 0.11 12.3 0.0 13 5.5 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 KPA40378.1 - 0.11 12.0 5.9 0.84 9.2 0.0 3.6 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.9 KPA40378.1 - 0.13 12.0 0.0 7.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_6 PF12774.7 KPA40378.1 - 0.19 10.6 0.2 2.5 7.0 0.0 2.6 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region Spc7 PF08317.11 KPA40378.1 - 1.2 8.0 15.8 0.039 12.8 9.3 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Mhr1 PF12829.7 KPA40379.1 - 1e-31 108.8 0.0 1.6e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination SVIP PF15811.5 KPA40379.1 - 0.16 12.4 1.1 0.3 11.6 1.1 1.4 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Sulfotransfer_3 PF13469.6 KPA40380.1 - 1.3e-08 35.5 0.0 2.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KPA40380.1 - 0.022 14.2 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain PDT PF00800.18 KPA40381.1 - 2e-58 197.2 0.0 2.5e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KPA40381.1 - 2.1e-05 24.2 0.0 0.00014 21.6 0.0 2.2 2 0 0 2 2 2 1 ACT domain Pkinase PF00069.25 KPA40382.1 - 1.9e-68 230.7 0.0 3e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40382.1 - 3e-48 164.4 0.0 5.3e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KPA40382.1 - 1e-27 96.4 0.0 2.2e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 KPA40382.1 - 7.1e-18 64.5 0.4 4.4e-17 61.9 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KPA40382.1 - 4.2e-16 59.1 0.1 7.6e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KPA40382.1 - 1.7e-14 54.2 0.0 3.5e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 KPA40382.1 - 2.3e-06 27.2 0.0 0.00034 20.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.16 KPA40382.1 - 0.0034 17.3 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Pkinase_fungal PF17667.1 KPA40382.1 - 0.015 14.1 0.5 0.033 13.0 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase SAM_4 PF18017.1 KPA40382.1 - 0.016 15.2 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) GGACT PF06094.12 KPA40383.1 - 2.6e-08 34.5 0.0 7.9e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KPA40383.1 - 9.8e-08 32.3 0.1 1.9e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 AIG2-like family ChaC PF04752.12 KPA40383.1 - 0.043 13.9 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 ChaC-like protein PrpF PF04303.13 KPA40384.1 - 2.4e-88 296.6 0.1 3e-88 296.3 0.1 1.0 1 0 0 1 1 1 1 PrpF protein RRM_1 PF00076.22 KPA40387.1 - 4e-16 58.6 0.0 5.5e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.9 KPA40388.1 - 1.5e-45 153.8 0.7 1.7e-45 153.6 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Histone_HNS PF00816.21 KPA40388.1 - 0.037 14.8 0.7 0.049 14.5 0.7 1.1 1 0 0 1 1 1 0 H-NS histone family Sedlin_N PF04628.13 KPA40389.1 - 7.6e-44 149.0 0.0 8.6e-44 148.8 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KPA40389.1 - 0.0012 18.8 0.1 0.041 13.8 0.0 2.1 1 1 1 2 2 2 1 Sybindin-like family HMG-CoA_red PF00368.18 KPA40389.1 - 0.17 10.9 0.0 0.19 10.7 0.0 1.0 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase Nairovirus_M PF07948.11 KPA40389.1 - 0.22 9.7 0.0 0.25 9.5 0.0 1.0 1 0 0 1 1 1 0 Nairovirus M polyprotein-like CENP-T_C PF15511.6 KPA40390.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KPA40390.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KPA40390.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KPA40390.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KPA40390.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KPA40390.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KPA40390.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KPA40390.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KPA40390.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region TPR_1 PF00515.28 KPA40391.1 - 8.7e-38 126.6 23.6 1.1e-07 31.4 0.0 10.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 KPA40391.1 - 1.4e-34 115.4 30.9 6.3e-06 25.9 0.1 11.1 10 1 1 11 11 11 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA40391.1 - 3.6e-31 107.2 24.1 8.7e-24 83.6 0.8 5.0 5 1 1 6 6 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KPA40391.1 - 1.5e-26 90.3 22.9 0.0029 17.7 0.0 11.2 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 KPA40391.1 - 2.2e-20 71.6 28.3 0.0098 16.6 0.2 10.7 5 2 7 12 12 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 KPA40391.1 - 2.5e-20 72.5 24.0 0.00081 19.6 1.3 9.0 6 2 1 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 KPA40391.1 - 7.4e-19 68.0 24.9 2.4e-05 24.8 5.0 7.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 KPA40391.1 - 1.2e-17 63.2 23.2 0.00011 21.7 2.0 9.2 7 2 4 11 11 10 6 TPR repeat TPR_17 PF13431.6 KPA40391.1 - 2.7e-17 61.8 20.9 0.06 13.7 0.0 9.5 10 1 0 10 10 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 KPA40391.1 - 1.1e-16 61.2 32.5 1.1e-07 32.3 0.9 8.2 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KPA40391.1 - 6.3e-16 57.2 14.3 0.0019 18.1 0.0 8.2 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 KPA40391.1 - 8.3e-11 41.8 20.7 0.68 10.7 0.0 10.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KPA40391.1 - 5e-09 36.2 12.1 0.045 13.9 1.3 6.3 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 KPA40391.1 - 0.00037 19.8 19.5 0.13 11.5 0.0 4.5 3 1 0 5 5 5 2 Tetratricopeptide repeat DUF2225 PF09986.9 KPA40391.1 - 0.0062 16.3 5.3 21 4.7 5.0 3.8 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Muraidase PF11860.8 KPA40391.1 - 0.048 13.9 2.3 1.4 9.1 0.0 3.0 2 1 1 3 3 3 0 N-acetylmuramidase TPR_20 PF14561.6 KPA40391.1 - 0.091 13.1 6.3 0.047 14.0 1.4 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPA40391.1 - 1.5 9.7 13.4 2.9 8.8 0.2 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KPA40391.1 - 2.5 8.2 6.8 4 7.6 0.3 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat SOG2 PF10428.9 KPA40391.1 - 6.8 5.8 13.8 9.8 5.2 13.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_S10 PF00338.22 KPA40392.1 - 7.3e-26 90.3 0.2 8.8e-26 90.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e TMEM208_SND2 PF05620.11 KPA40393.1 - 1.8e-51 174.3 0.0 2e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF1467 PF07330.12 KPA40393.1 - 0.018 15.0 0.4 0.032 14.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) DUF3605 PF12239.8 KPA40394.1 - 1.3e-53 181.4 0.0 1.7e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) DUF4866 PF16160.5 KPA40394.1 - 0.036 13.4 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4866) Say1_Mug180 PF10340.9 KPA40395.1 - 1.7e-19 70.0 0.0 2.1e-18 66.4 0.0 2.0 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KPA40395.1 - 5.5e-19 68.9 0.0 7.7e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold CBFD_NFYB_HMF PF00808.23 KPA40396.1 - 1.2e-12 47.9 0.9 1.8e-12 47.4 0.9 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KPA40396.1 - 0.043 14.2 6.4 0.043 14.2 0.1 3.0 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 KPA40396.1 - 0.17 12.0 0.5 0.34 11.0 0.5 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region CENP-X PF09415.10 KPA40396.1 - 2.9 8.3 5.1 9.3 6.7 0.3 2.2 2 0 0 2 2 2 0 CENP-S associating Centromere protein X PI3_PI4_kinase PF00454.27 KPA40397.1 - 4.6e-34 118.4 0.0 1.4e-33 116.8 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KPA40397.1 - 1.2e-20 73.2 0.6 2.7e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 zf-C3HC4_3 PF13920.6 KPA40398.1 - 0.0012 18.7 11.9 0.0018 18.1 11.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KPA40398.1 - 0.25 11.3 6.4 0.41 10.5 6.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KPA40398.1 - 7 6.7 12.5 11 6.0 12.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Ras PF00071.22 KPA40399.1 - 4.9e-57 192.1 0.0 5.8e-57 191.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA40399.1 - 3.2e-34 117.7 0.0 4.8e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA40399.1 - 3.8e-14 52.5 0.0 5.9e-14 51.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPA40399.1 - 1.4e-05 24.7 0.0 2.5e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KPA40399.1 - 8.5e-05 22.6 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KPA40399.1 - 0.00014 21.3 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KPA40399.1 - 0.00048 20.5 0.1 0.00091 19.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 KPA40399.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KPA40399.1 - 0.16 11.8 0.0 1.8 8.5 0.0 2.1 2 1 0 2 2 2 0 RsgA GTPase Kri1 PF05178.12 KPA40400.1 - 4.3e-31 107.5 23.4 4.3e-31 107.5 23.4 6.0 7 3 1 8 8 8 1 KRI1-like family Kri1_C PF12936.7 KPA40400.1 - 3.7e-28 97.6 0.3 3.7e-28 97.6 0.3 4.3 4 1 1 5 5 5 1 KRI1-like family C-terminal DUF4381 PF14316.6 KPA40400.1 - 0.11 12.8 4.7 0.36 11.1 4.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Fungal_trans PF04082.18 KPA40401.1 - 2.6e-29 102.1 0.0 1.1e-28 100.0 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA40401.1 - 2e-09 37.4 10.9 3.2e-09 36.8 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 KPA40402.1 - 3.4e-09 36.9 0.0 5.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA40402.1 - 4.7e-07 29.5 0.0 5.7e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KPA40402.1 - 0.00014 22.3 0.0 0.00023 21.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KPA40402.1 - 0.00047 19.3 0.0 0.001 18.2 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KPA40402.1 - 0.052 13.1 0.3 0.12 11.9 0.1 1.8 3 0 0 3 3 3 0 NmrA-like family DUF924 PF06041.11 KPA40403.1 - 2.7e-21 76.5 0.0 4.7e-21 75.7 0.0 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Macoilin PF09726.9 KPA40404.1 - 6 5.3 6.6 8.2 4.8 6.6 1.1 1 0 0 1 1 1 0 Macoilin family PBP1_TM PF14812.6 KPA40406.1 - 0.087 13.2 3.4 2.5 8.5 0.7 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Porphobil_deam PF01379.20 KPA40407.1 - 1.4e-56 191.2 0.0 2.2e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KPA40407.1 - 3.5e-12 46.5 0.0 8.3e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Methyltransf_23 PF13489.6 KPA40410.1 - 5.6e-16 58.8 0.0 1.4e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40410.1 - 3.8e-10 40.3 0.0 1.5e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA40410.1 - 8.9e-09 35.9 0.0 8.7e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA40410.1 - 5.9e-07 30.2 0.0 2.4e-05 25.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA40410.1 - 0.021 14.6 0.0 0.4 10.5 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 KPA40410.1 - 0.033 13.5 0.0 2 7.7 0.0 3.0 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KPA40410.1 - 0.058 12.9 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.12 KPA40410.1 - 0.062 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.14 KPA40410.1 - 0.15 11.6 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DUF5410 PF17422.2 KPA40412.1 - 0.064 12.5 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5410) S_locus_glycop PF00954.20 KPA40413.1 - 0.0019 18.7 0.4 0.0025 18.3 0.4 1.2 1 0 0 1 1 1 1 S-locus glycoprotein domain Dickkopf_N PF04706.12 KPA40413.1 - 7.5 7.1 9.7 33 5.1 0.5 3.3 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region MFS_1 PF07690.16 KPA40414.1 - 4.1e-17 62.1 30.1 4.8e-16 58.6 30.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_23 PF13489.6 KPA40415.1 - 1.1e-21 77.3 0.0 1.6e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40415.1 - 1.8e-10 41.3 0.0 8.1e-10 39.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA40415.1 - 5.4e-08 32.8 0.0 1.1e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA40415.1 - 9.2e-08 32.6 0.0 2.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA40415.1 - 9.3e-07 29.5 0.0 1.4e-05 25.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KPA40415.1 - 9.1e-05 22.6 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KPA40415.1 - 0.0036 16.9 0.0 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KPA40415.1 - 0.089 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KPA40415.1 - 0.13 11.6 0.0 0.47 9.8 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.16 KPA40417.1 - 0.00035 19.6 11.7 0.00047 19.2 11.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sulfatase PF00884.23 KPA40418.1 - 6.6e-29 101.3 1.2 8.3e-29 100.9 1.2 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPA40418.1 - 0.00015 21.5 0.2 0.00018 21.3 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF3425 PF11905.8 KPA40419.1 - 1.1e-19 70.6 0.3 2.8e-19 69.3 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.25 KPA40419.1 - 1.6e-18 66.9 0.0 2.6e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA40419.1 - 1.4e-09 37.9 0.0 3.6e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA40419.1 - 0.0026 17.7 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Csm1_B PF18211.1 KPA40419.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Csm1 subunit domain B HET PF06985.11 KPA40420.1 - 1.1e-26 93.9 0.0 2.2e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KPA40420.1 - 3.8e-15 56.0 0.0 6.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40420.1 - 4.7e-08 32.6 0.0 7.2e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PsaD PF02531.16 KPA40420.1 - 0.0081 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 PsaD Kinase-like PF14531.6 KPA40420.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PI-PLC-X PF00388.19 KPA40422.1 - 5.4e-08 32.5 0.0 9.8e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain BNR_2 PF13088.6 KPA40422.1 - 0.00027 20.3 4.0 0.00036 19.9 4.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain Ring_hydroxyl_B PF00866.18 KPA40423.1 - 0.12 12.4 1.5 0.25 11.4 1.5 1.4 1 0 0 1 1 1 0 Ring hydroxylating beta subunit Lipase_GDSL_2 PF13472.6 KPA40424.1 - 2e-21 77.2 0.9 3.4e-21 76.4 0.9 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA40424.1 - 7.5e-08 32.6 0.2 9e-07 29.1 0.2 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GST_N_2 PF13409.6 KPA40425.1 - 2.9e-09 37.1 0.0 5.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPA40425.1 - 7.6e-07 29.5 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPA40425.1 - 0.013 15.7 0.1 0.029 14.6 0.1 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Abhydrolase_3 PF07859.13 KPA40426.1 - 1.3e-35 123.2 0.0 1.6e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPA40426.1 - 2.1e-06 26.9 0.0 3.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase p450 PF00067.22 KPA40427.1 - 3.2e-73 247.1 0.0 4e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mg_trans_NIPA PF05653.14 KPA40428.1 - 1.3e-93 313.3 26.1 1.9e-93 312.8 26.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA U-box PF04564.15 KPA40428.1 - 1.4e-19 70.0 0.0 2.6e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain EamA PF00892.20 KPA40428.1 - 1e-06 29.0 9.0 1e-06 29.0 9.0 3.0 3 0 0 3 3 3 1 EamA-like transporter family TPR_19 PF14559.6 KPA40428.1 - 0.00044 20.7 7.7 0.17 12.4 1.7 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPA40428.1 - 0.0016 18.7 6.0 0.038 14.4 0.9 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KPA40428.1 - 0.0055 16.4 7.4 0.057 13.1 0.4 2.9 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 KPA40428.1 - 0.013 15.6 13.0 1.8 8.9 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPA40428.1 - 0.05 13.4 7.1 10 6.2 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPA40428.1 - 0.072 13.8 6.4 1.9 9.2 1.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF87 PF01935.17 KPA40428.1 - 0.083 13.0 0.5 0.19 11.8 0.5 1.6 1 1 0 1 1 1 0 Helicase HerA, central domain TPR_14 PF13428.6 KPA40428.1 - 0.34 11.8 4.4 6.5 7.9 0.2 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat SLC35F PF06027.12 KPA40428.1 - 0.67 9.4 19.4 1 8.8 19.4 1.2 1 0 0 1 1 1 0 Solute carrier family 35 DUF805 PF05656.14 KPA40428.1 - 3.2 8.2 12.1 1.6 9.1 3.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF805) ST7 PF04184.12 KPA40428.1 - 3.2 6.1 6.9 3.9 5.8 3.2 2.3 2 0 0 2 2 2 0 ST7 protein CHIP_TPR_N PF18391.1 KPA40428.1 - 3.9 8.3 20.5 0.13 13.0 13.4 2.2 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Band_3_cyto PF07565.13 KPA40429.1 - 0.14 12.0 8.2 0.017 15.0 3.5 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Dynamin_N PF00350.23 KPA40429.1 - 0.26 11.3 0.7 0.57 10.2 0.7 1.6 1 0 0 1 1 1 0 Dynamin family MRP-S26 PF14943.6 KPA40429.1 - 1.1 9.1 29.4 2.8 7.8 16.4 2.5 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Paf1 PF03985.13 KPA40429.1 - 2.3 7.1 32.9 0.64 9.0 26.1 2.2 2 0 0 2 2 2 0 Paf1 CFEM PF05730.11 KPA40430.1 - 2.3e-07 30.8 4.8 3.8e-07 30.1 4.8 1.3 1 0 0 1 1 1 1 CFEM domain Podoplanin PF05808.11 KPA40430.1 - 0.0004 20.5 0.2 0.0006 20.0 0.2 1.3 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 KPA40430.1 - 0.0022 17.4 2.3 0.0023 17.3 0.5 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF5305 PF17231.2 KPA40430.1 - 0.013 15.0 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) NICE-1 PF15845.5 KPA40430.1 - 0.014 16.2 3.5 5.8 7.8 0.0 2.7 2 1 1 3 3 3 0 Cysteine-rich C-terminal 1 family Rax2 PF12768.7 KPA40430.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM51 PF15345.6 KPA40430.1 - 0.022 14.6 2.1 0.025 14.4 0.1 2.2 1 1 1 2 2 2 0 Transmembrane protein 51 CoatB PF10389.9 KPA40430.1 - 0.045 13.6 0.1 0.045 13.6 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage coat protein B LapA_dom PF06305.11 KPA40430.1 - 0.1 12.4 0.5 0.18 11.7 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MID_MedPIWI PF18296.1 KPA40430.1 - 0.44 10.3 2.2 0.68 9.7 2.2 1.3 1 0 0 1 1 1 0 MID domain of medPIWI Fungal_trans PF04082.18 KPA40432.1 - 2.5e-16 59.5 0.4 4.3e-16 58.8 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain NmrA PF05368.13 KPA40433.1 - 2.1e-34 119.1 0.1 2.8e-34 118.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA40433.1 - 1.7e-15 57.4 0.1 2.3e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA40433.1 - 8e-05 22.2 0.0 0.0068 15.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPA40433.1 - 0.00025 21.0 0.0 0.00056 19.9 0.0 1.5 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KPA40433.1 - 0.0017 17.9 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPA40433.1 - 0.0018 17.4 0.0 0.0046 16.0 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KPA40433.1 - 0.0091 15.5 0.1 0.033 13.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KPA40433.1 - 0.077 12.2 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein DapB_N PF01113.20 KPA40433.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DHO_dh PF01180.21 KPA40434.1 - 6.9e-69 232.3 0.0 1.9e-68 230.9 0.0 1.6 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.17 KPA40434.1 - 0.0019 17.7 2.3 0.37 10.2 0.1 2.3 2 0 0 2 2 2 2 PcrB family PEP_hydrolase PF09370.10 KPA40434.1 - 0.064 12.5 0.1 0.13 11.4 0.1 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Rho_Binding PF08912.11 KPA40435.1 - 0.0031 18.3 6.6 0.087 13.6 2.9 2.3 2 0 0 2 2 2 1 Rho Binding Borrelia_lipo_1 PF05714.11 KPA40435.1 - 0.0053 16.6 4.1 0.81 9.4 1.1 2.1 1 1 1 2 2 2 2 Borrelia burgdorferi virulent strain associated lipoprotein Snapin_Pallidin PF14712.6 KPA40435.1 - 0.011 16.1 7.3 0.034 14.6 0.9 2.6 2 1 0 2 2 2 0 Snapin/Pallidin Dak2 PF02734.17 KPA40435.1 - 0.033 14.1 1.4 2.5 8.0 0.1 2.1 1 1 1 2 2 2 0 DAK2 domain vWA-TerF-like PF10138.9 KPA40435.1 - 0.054 13.6 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus Cnn_1N PF07989.11 KPA40435.1 - 0.12 12.6 11.6 0.11 12.7 5.3 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF948 PF06103.11 KPA40435.1 - 0.12 12.6 0.5 0.78 10.0 0.1 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PilJ PF13675.6 KPA40435.1 - 0.15 12.1 3.5 1.7 8.7 0.2 2.6 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ANAPC2 PF08672.11 KPA40435.1 - 0.53 10.8 2.6 31 5.2 0.0 3.2 3 1 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 KxDL PF10241.9 KPA40435.1 - 0.73 10.2 6.4 0.46 10.8 1.6 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein THOC7 PF05615.13 KPA40435.1 - 1.6 9.0 11.5 8.5 6.7 11.6 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 YabA PF06156.13 KPA40435.1 - 3.8 8.2 10.7 5.5 7.7 4.9 2.6 1 1 2 3 3 3 0 Initiation control protein YabA E1-E2_ATPase PF00122.20 KPA40437.1 - 1.6e-44 151.6 3.7 4.3e-44 150.2 3.7 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KPA40437.1 - 1.1e-21 78.1 0.0 2.3e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KPA40437.1 - 1.8e-05 25.1 0.8 0.00017 22.0 0.0 2.9 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KPA40437.1 - 0.00056 19.7 0.2 0.0037 17.0 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AsnC_trans_reg PF01037.21 KPA40437.1 - 0.15 12.0 0.1 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain Exo5 PF09810.9 KPA40438.1 - 2.5e-139 464.9 0.0 3.1e-139 464.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Oxidored_FMN PF00724.20 KPA40439.1 - 2.3e-67 227.7 0.0 2.9e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KPA40439.1 - 1.2e-05 24.5 0.0 4.2e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) G-patch PF01585.23 KPA40440.1 - 7e-08 32.2 0.2 1.5e-07 31.2 0.2 1.6 1 0 0 1 1 1 1 G-patch domain UPF0547 PF10571.9 KPA40440.1 - 0.071 13.2 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 G-patch_2 PF12656.7 KPA40440.1 - 0.27 11.4 0.1 0.27 11.4 0.1 2.8 4 0 0 4 4 4 0 G-patch domain Sec1 PF00995.23 KPA40441.1 - 1.5e-116 390.9 0.0 1.8e-116 390.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2852 PF11014.8 KPA40442.1 - 3.2 7.9 5.5 0.41 10.8 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) GST_N_2 PF13409.6 KPA40443.1 - 5.2e-20 71.5 0.0 1.4e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPA40443.1 - 1.6e-14 53.7 0.0 3.1e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPA40443.1 - 4.3e-07 30.2 0.2 1.5e-05 25.4 0.2 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPA40443.1 - 4.8e-06 26.7 0.0 9.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA40443.1 - 0.001 19.2 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ThiF PF00899.21 KPA40444.1 - 1.2e-109 365.4 0.0 3.7e-73 245.9 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KPA40444.1 - 5.4e-93 311.5 2.6 8.5e-93 310.9 2.6 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KPA40444.1 - 1.6e-31 108.3 0.1 3.8e-31 107.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KPA40444.1 - 7.9e-31 106.6 0.1 1.5e-30 105.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KPA40444.1 - 1.5e-24 86.0 2.1 2.5e-24 85.3 0.8 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 KPA40444.1 - 0.0056 17.1 0.0 0.064 13.7 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding FeoB_Cyto PF17910.1 KPA40444.1 - 0.11 13.1 0.0 0.3 11.6 0.0 1.8 1 0 0 1 1 1 0 FeoB cytosolic helical domain FKBP_C PF00254.28 KPA40445.1 - 2.2e-28 98.4 0.1 3e-28 98.0 0.1 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase C2 PF00168.30 KPA40446.1 - 1.2e-09 38.4 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain 4HBT PF03061.22 KPA40447.1 - 2.7e-09 37.3 0.0 4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Dicty_CAR PF05462.11 KPA40448.1 - 2.2e-08 33.6 8.0 4e-08 32.8 8.0 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 KPA40448.1 - 6.3e-07 28.9 12.6 1e-06 28.3 12.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 KPA40448.1 - 6.2e-05 22.5 1.8 9.6e-05 21.8 1.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KPA40448.1 - 0.0015 18.4 11.4 0.0028 17.5 11.4 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KPA40448.1 - 0.9 9.7 8.0 0.29 11.2 0.6 2.5 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term NAD_binding_10 PF13460.6 KPA40449.1 - 1.8e-22 80.1 0.0 2.3e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA40449.1 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Inv-AAD PF18785.1 KPA40450.1 - 2.1e-57 192.6 0.1 3e-57 192.1 0.1 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KPA40450.1 - 1.8e-12 47.0 0.0 2.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KPA40450.1 - 0.045 13.5 0.0 0.086 12.6 0.0 1.4 1 1 0 1 1 1 0 MafB19-like deaminase DnaJ PF00226.31 KPA40451.1 - 1.4e-22 79.6 1.6 4e-22 78.1 1.6 1.8 1 0 0 1 1 1 1 DnaJ domain WYL_3 PF18488.1 KPA40451.1 - 0.0089 16.4 0.2 0.025 14.9 0.2 1.8 1 0 0 1 1 1 1 WYL domain Nif11 PF07862.11 KPA40451.1 - 0.013 15.8 0.1 0.76 10.1 0.0 3.5 3 0 0 3 3 3 0 Nif11 domain ArfA PF03889.13 KPA40451.1 - 0.035 13.6 2.3 0.035 13.6 2.3 2.5 3 0 0 3 3 3 0 Alternative ribosome-rescue factor A Stn1 PF10451.9 KPA40452.1 - 6.2e-16 58.1 1.2 3.9e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KPA40452.1 - 0.012 15.5 0.2 0.11 12.5 0.2 2.2 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain Cid2 PF09774.9 KPA40452.1 - 0.026 14.9 7.4 0.039 14.4 7.4 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 Dynactin_p62 PF05502.13 KPA40452.1 - 0.063 12.1 2.1 0.089 11.6 2.1 1.1 1 0 0 1 1 1 0 Dynactin p62 family MCM_bind PF09739.9 KPA40452.1 - 0.33 9.4 3.7 0.43 9.0 3.7 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF2058 PF09831.9 KPA40452.1 - 0.56 10.3 6.8 0.9 9.7 6.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Borrelia_P83 PF05262.11 KPA40452.1 - 0.82 8.1 10.1 1.1 7.7 10.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Glyco_hydro81C PF17652.1 KPA40453.1 - 3.1e-156 520.0 16.5 4.2e-156 519.5 16.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KPA40453.1 - 4.1e-107 358.1 5.4 6.4e-107 357.4 5.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Na_Ca_ex PF01699.24 KPA40454.1 - 6.4e-44 149.6 36.4 1.1e-22 80.6 17.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Utp14 PF04615.13 KPA40455.1 - 1.5e-182 609.1 65.7 1.5e-182 609.1 65.7 2.3 1 1 1 2 2 2 1 Utp14 protein COX15-CtaA PF02628.15 KPA40456.1 - 2.5e-111 371.9 6.8 3e-111 371.6 6.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein NADH-u_ox-rdase PF10785.9 KPA40456.1 - 0.091 13.5 3.9 16 6.3 0.0 3.8 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit tRNA-synt_2 PF00152.20 KPA40457.1 - 7.7e-75 251.9 0.9 1e-74 251.5 0.9 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KPA40457.1 - 4.5e-11 42.6 0.1 8.8e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KPA40457.1 - 6.8e-07 29.0 0.1 0.0029 17.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-Di19 PF05605.12 KPA40458.1 - 0.029 14.7 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Chibby PF14645.6 KPA40458.1 - 0.045 14.2 1.3 0.17 12.3 1.3 2.1 1 0 0 1 1 1 0 Chibby family zf-C2H2_4 PF13894.6 KPA40458.1 - 0.089 13.7 0.1 0.19 12.7 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KPA40458.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Kre28 PF17097.5 KPA40458.1 - 0.19 10.7 4.3 0.38 9.7 4.3 1.4 1 0 0 1 1 1 0 Spindle pole body component KCT2 PF17818.1 KPA40458.1 - 0.27 11.3 3.2 0.95 9.6 3.2 1.9 1 0 0 1 1 1 0 Keratinocyte-associated gene product UPF0242 PF06785.11 KPA40458.1 - 0.31 11.1 7.3 0.98 9.5 7.3 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PPP4R2 PF09184.11 KPA40458.1 - 0.88 9.1 9.4 1.6 8.3 9.4 1.4 1 0 0 1 1 1 0 PPP4R2 Atg14 PF10186.9 KPA40458.1 - 7.7 5.5 13.7 0.77 8.8 8.7 1.9 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Chromo_shadow PF01393.19 KPA40459.1 - 1.8e-18 66.4 2.9 4.7e-16 58.6 0.5 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KPA40459.1 - 7.8e-13 48.1 1.3 7.8e-13 48.1 1.3 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DNase_NucA_NucB PF14040.6 KPA40459.1 - 0.077 13.4 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB ELM2 PF01448.24 KPA40459.1 - 2.8 8.8 4.9 23 5.8 2.6 2.5 2 1 0 2 2 2 0 ELM2 domain Suc_Fer-like PF06999.12 KPA40462.1 - 1.3e-67 227.4 0.0 1.6e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Acyltransferase PF01553.21 KPA40463.1 - 1.3e-08 34.6 0.0 0.00037 20.1 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase BRAP2 PF07576.12 KPA40464.1 - 2.7e-29 101.3 0.0 4.4e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KPA40464.1 - 2e-17 63.2 9.4 2e-17 63.2 9.4 2.1 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KPA40464.1 - 1.5e-08 34.9 9.5 1.5e-08 34.9 9.5 2.5 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KPA40464.1 - 7.3e-07 28.8 5.1 7.3e-07 28.8 5.1 2.2 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KPA40464.1 - 3.8e-06 26.6 9.8 1.2e-05 25.1 9.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA40464.1 - 1.5e-05 24.7 8.6 1.5e-05 24.7 8.6 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA40464.1 - 3.7e-05 23.6 4.1 3.7e-05 23.6 4.1 2.6 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPA40464.1 - 4.1e-05 23.4 7.6 4.1e-05 23.4 7.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KPA40464.1 - 0.0011 18.8 6.6 0.0011 18.8 6.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KPA40464.1 - 0.0012 19.1 6.7 0.004 17.4 6.7 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF4164 PF13747.6 KPA40464.1 - 0.023 15.0 9.5 1.2 9.5 9.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF4710 PF15828.5 KPA40464.1 - 0.041 14.0 1.1 0.12 12.6 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) DUF2564 PF10819.8 KPA40464.1 - 0.1 13.0 1.8 0.21 12.0 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) COG5 PF10392.9 KPA40464.1 - 0.16 12.2 6.2 0.27 11.4 6.2 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 KPA40464.1 - 1.5 8.1 7.1 2.3 7.5 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KPA40464.1 - 1.6 8.9 11.9 1.6 8.9 7.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Erp_C PF06780.11 KPA40464.1 - 4 7.5 6.8 7.9 6.5 6.8 1.5 1 0 0 1 1 1 0 Erp protein C-terminus Prok-RING_4 PF14447.6 KPA40464.1 - 6.9 6.6 22.6 0.082 12.8 11.0 2.9 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KPA40464.1 - 9.3 6.2 11.5 0.11 12.4 3.6 1.8 2 0 0 2 2 1 0 zf-RING of BARD1-type protein ubiquitin PF00240.23 KPA40465.1 - 9.5e-69 227.1 6.2 7.8e-34 115.3 0.6 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 KPA40465.1 - 3.9e-33 113.1 6.5 4.8e-16 58.3 0.7 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KPA40465.1 - 1.5e-12 47.8 1.8 0.00011 22.5 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KPA40465.1 - 1.7e-08 34.7 0.4 0.0066 16.8 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 KPA40465.1 - 2.3e-08 33.8 0.3 0.0077 16.1 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KPA40465.1 - 2e-07 31.1 0.4 0.034 14.3 0.1 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KPA40465.1 - 2.4e-06 28.0 0.1 0.11 13.1 0.0 2.2 1 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KPA40465.1 - 1.1e-05 25.4 0.1 0.12 12.2 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KPA40465.1 - 3e-05 24.0 8.0 5.8 7.0 0.2 4.0 4 0 0 4 4 4 4 Ubiquitin-like domain DUF3861 PF12977.7 KPA40465.1 - 0.0044 17.1 0.2 3.2 8.0 0.0 2.2 1 1 1 2 2 2 2 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 KPA40465.1 - 0.0055 16.5 0.5 3.8 7.4 0.0 2.4 2 0 0 2 2 2 2 ACT domain DUF2870 PF11069.8 KPA40465.1 - 0.015 15.7 0.0 11 6.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) YcgR_2 PF12945.7 KPA40465.1 - 0.027 14.6 0.4 9.7 6.4 0.1 2.3 2 0 0 2 2 2 0 Flagellar protein YcgR Big_7 PF17957.1 KPA40465.1 - 0.046 14.5 0.0 17 6.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig domain UN_NPL4 PF11543.8 KPA40465.1 - 0.069 13.6 0.2 16 6.0 0.0 2.4 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Tash_PEST PF07708.11 KPA40465.1 - 0.18 12.0 9.6 2.7 8.2 1.5 2.3 2 0 0 2 2 2 0 Tash protein PEST motif DUF969 PF06149.12 KPA40465.1 - 0.2 11.1 0.0 6.9 6.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF969) FERM_f0 PF16511.5 KPA40465.1 - 0.2 12.0 1.3 37 4.7 0.1 3.2 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM Plexin_cytopl PF08337.12 KPA40465.1 - 0.45 9.1 5.4 4.8 5.7 0.4 2.9 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain Zn_clus PF00172.18 KPA40466.1 - 0.0037 17.4 7.7 0.008 16.3 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KPA40467.1 - 0.013 15.4 0.1 0.045 13.7 0.1 1.9 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KPA40467.1 - 0.083 12.8 0.4 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 F-box F-box PF00646.33 KPA40467.1 - 0.16 11.9 1.3 0.6 10.1 1.3 2.0 1 0 0 1 1 1 0 F-box domain Cu_bind_like PF02298.17 KPA40468.1 - 0.0032 17.4 0.0 0.0092 16.0 0.0 1.7 1 1 0 1 1 1 1 Plastocyanin-like domain Glyco_hydro_39 PF01229.17 KPA40468.1 - 0.12 11.0 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 SMN PF06003.12 KPA40469.1 - 1.2e-05 24.8 10.2 0.00012 21.4 0.5 2.7 1 1 2 3 3 3 2 Survival motor neuron protein (SMN) RP854 PF17460.2 KPA40469.1 - 0.029 14.1 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein RP854 THEG4 PF15834.5 KPA40469.1 - 0.14 12.2 0.6 0.19 11.7 0.6 1.1 1 0 0 1 1 1 0 Testis highly expressed protein 4 RRM_1 PF00076.22 KPA40470.1 - 4.8e-15 55.1 0.0 1.3e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPA40470.1 - 0.0017 18.3 0.1 0.0039 17.2 0.1 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KPA40470.1 - 0.092 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Limkain b1 DUF1192 PF06698.11 KPA40472.1 - 0.0047 16.9 0.4 0.0084 16.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) DUF812 PF05667.11 KPA40472.1 - 0.0088 15.0 0.4 0.012 14.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Ada3 PF10198.9 KPA40472.1 - 0.066 13.4 0.2 0.12 12.6 0.1 1.4 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 MWFE PF15879.5 KPA40472.1 - 0.088 13.0 1.3 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF3450 PF11932.8 KPA40472.1 - 0.1 11.9 1.3 0.16 11.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) WD40 PF00400.32 KPA40473.1 - 9.5e-25 86.4 7.7 0.00039 21.2 0.0 7.6 9 0 0 9 9 9 5 WD domain, G-beta repeat F-box-like PF12937.7 KPA40473.1 - 6.2e-13 48.4 1.2 9e-13 47.9 0.3 1.9 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KPA40473.1 - 3.3e-05 24.1 0.1 4.7 7.6 0.0 4.4 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KPA40473.1 - 0.00026 20.8 0.2 0.00097 19.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 KPA40473.1 - 0.0047 15.6 0.1 0.086 11.5 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 F-box_4 PF15966.5 KPA40473.1 - 0.0085 16.0 0.6 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 F-box SmpA_OmlA PF04355.13 KPA40473.1 - 0.0095 15.7 0.5 0.43 10.4 0.1 2.8 3 0 0 3 3 3 1 SmpA / OmlA family MgtE_N PF03448.17 KPA40473.1 - 0.018 15.6 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain PALB2_WD40 PF16756.5 KPA40473.1 - 0.2 10.5 0.1 2.5 7.0 0.0 2.5 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Clr5 PF14420.6 KPA40474.1 - 7e-12 45.4 0.6 1.4e-11 44.4 0.6 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KPA40474.1 - 1.4e-09 38.1 0.9 5.4e-06 26.6 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KPA40474.1 - 0.0015 18.4 3.5 0.0029 17.4 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KPA40474.1 - 0.0043 16.5 0.1 0.006 16.0 0.1 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 KPA40474.1 - 0.0074 16.4 0.3 0.06 13.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KPA40474.1 - 0.02 14.7 0.1 0.099 12.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPA40474.1 - 0.021 14.9 0.5 0.074 13.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPA40474.1 - 0.061 14.2 0.2 0.44 11.5 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPA40474.1 - 0.12 13.0 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat 3-PAP PF12578.8 KPA40475.1 - 0.16 11.7 1.3 0.25 11.1 1.0 1.4 1 1 0 1 1 1 0 Myotubularin-associated protein Fungal_trans PF04082.18 KPA40476.1 - 3.9e-09 35.9 0.0 6.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA40476.1 - 6.7e-09 35.7 12.3 1.2e-08 34.9 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPA40477.1 - 1.6e-36 126.0 46.1 3.6e-29 101.8 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KPA40477.1 - 4.3 5.5 10.8 1 7.6 7.8 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF829 PF05705.14 KPA40478.1 - 3e-52 177.9 0.0 3.5e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) zf-C2H2 PF00096.26 KPA40479.1 - 0.00065 20.0 16.0 0.0083 16.5 0.9 7.2 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA40479.1 - 0.013 16.3 1.2 0.013 16.3 1.2 7.8 9 0 0 9 9 9 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KPA40479.1 - 0.031 14.3 0.8 0.031 14.3 0.8 3.8 4 1 1 5 5 5 0 C2H2-type zinc finger zf-met PF12874.7 KPA40479.1 - 0.84 10.1 5.5 2.5 8.6 1.2 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PH_10 PF15411.6 KPA40482.1 - 8.1e-40 135.9 0.4 1.7e-39 134.9 0.4 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 KPA40482.1 - 2.5e-32 111.0 0.1 5e-32 110.0 0.1 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 KPA40482.1 - 4.1e-28 98.9 0.2 7.5e-28 98.0 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KPA40482.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain DUF5645 PF18713.1 KPA40482.1 - 0.023 15.0 0.0 0.082 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5645) PH PF00169.29 KPA40482.1 - 0.055 14.0 0.8 0.17 12.4 0.8 1.8 1 1 0 1 1 1 0 PH domain Euplotes_phero PF05842.11 KPA40483.1 - 0.074 13.6 0.1 0.08 13.5 0.1 1.1 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein zf-LITAF-like PF10601.9 KPA40484.1 - 1.7e-19 69.8 7.2 2.4e-19 69.4 7.2 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DNA_RNApol_7kD PF03604.13 KPA40484.1 - 0.031 14.0 0.5 0.93 9.2 0.0 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 KPA40484.1 - 2.4 8.3 9.1 7.2 6.7 0.3 2.4 1 1 1 2 2 2 0 Double zinc ribbon Rtt106 PF08512.12 KPA40485.1 - 4.8e-32 110.2 0.0 1.6e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KPA40485.1 - 0.00081 19.4 0.0 0.002 18.1 0.0 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain SDA1 PF05285.12 KPA40485.1 - 0.0083 15.6 36.7 0.012 15.1 36.7 1.1 1 0 0 1 1 1 1 SDA1 bPH_2 PF03703.14 KPA40485.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain Nop14 PF04147.12 KPA40485.1 - 0.13 10.4 37.0 0.2 9.8 37.0 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KPA40485.1 - 4.5 6.5 38.1 6.8 5.9 38.1 1.2 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.10 KPA40486.1 - 4.7e-23 82.5 7.6 3.8e-12 46.9 0.7 2.0 1 1 1 2 2 2 2 AAA-ATPase Vps4-associated protein 1 Snf7 PF03357.21 KPA40487.1 - 7.9e-44 149.3 11.8 9.5e-44 149.0 11.8 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KPA40487.1 - 1e-05 25.9 4.1 0.026 15.0 1.8 3.0 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 KPA40487.1 - 0.0012 18.9 14.2 0.12 12.3 12.6 2.6 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 KPA40487.1 - 0.0037 14.9 8.3 0.0048 14.5 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Zwint PF15556.6 KPA40487.1 - 0.004 16.7 6.3 0.0052 16.3 6.3 1.3 1 0 0 1 1 1 1 ZW10 interactor Wtap PF17098.5 KPA40487.1 - 0.0078 16.1 8.3 0.043 13.7 8.3 1.9 1 1 0 1 1 1 1 WTAP/Mum2p family CLZ PF16526.5 KPA40487.1 - 0.0096 16.3 14.5 0.02 15.2 0.0 4.0 4 1 1 5 5 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 KPA40487.1 - 0.013 15.5 7.5 1 9.4 3.6 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3723 PF12520.8 KPA40487.1 - 0.019 13.7 0.7 0.023 13.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) Mod_r PF07200.13 KPA40487.1 - 0.032 14.3 10.8 0.02 15.0 6.2 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2205 PF10224.9 KPA40487.1 - 0.038 14.0 7.9 0.051 13.6 1.9 3.1 2 1 1 3 3 3 0 Short coiled-coil protein DUF5082 PF16888.5 KPA40487.1 - 0.043 14.1 11.4 0.09 13.1 10.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) FliD_C PF07195.12 KPA40487.1 - 0.049 13.0 7.0 0.14 11.5 0.0 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus SlyX PF04102.12 KPA40487.1 - 0.049 14.2 8.7 0.36 11.5 0.1 3.5 1 1 3 4 4 4 0 SlyX DUF4988 PF16378.5 KPA40487.1 - 0.049 13.3 2.9 0.24 11.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function FapA PF03961.13 KPA40487.1 - 0.052 12.1 11.0 0.29 9.7 3.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 KPA40487.1 - 0.055 13.5 4.6 0.12 12.4 2.9 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 KPA40487.1 - 0.11 11.0 1.4 0.24 9.9 0.8 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family Sec34 PF04136.15 KPA40487.1 - 0.13 12.1 2.8 0.22 11.4 0.4 2.1 2 0 0 2 2 2 0 Sec34-like family DUF4407 PF14362.6 KPA40487.1 - 0.16 11.3 8.3 0.25 10.7 8.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KPA40487.1 - 0.17 12.4 17.0 1.6 9.2 6.0 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 KPA40487.1 - 0.24 11.0 3.3 0.31 10.6 3.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF848 PF05852.11 KPA40487.1 - 0.25 11.5 7.8 0.22 11.6 5.4 2.1 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) XhlA PF10779.9 KPA40487.1 - 0.31 11.3 9.9 1.1 9.5 0.0 3.5 2 1 1 3 3 3 0 Haemolysin XhlA Muted PF14942.6 KPA40487.1 - 0.33 11.3 11.4 2.7 8.3 5.8 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Prefoldin_2 PF01920.20 KPA40487.1 - 0.38 10.7 15.6 0.47 10.4 0.0 4.1 3 1 0 3 3 2 0 Prefoldin subunit DUF4094 PF13334.6 KPA40487.1 - 0.42 11.1 6.7 2.6 8.5 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Tropomyosin_1 PF12718.7 KPA40487.1 - 0.65 10.1 14.9 0.059 13.5 2.1 2.6 1 1 2 3 3 3 0 Tropomyosin like YabA PF06156.13 KPA40487.1 - 0.88 10.2 10.8 10 6.9 1.0 2.7 1 1 1 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 KPA40487.1 - 0.95 9.9 14.7 8.7 6.8 0.0 4.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) NYD-SP28_assoc PF14775.6 KPA40487.1 - 1.1 9.5 6.5 6.3 7.0 0.6 3.1 2 1 1 3 3 3 0 Sperm tail C-terminal domain Med4 PF10018.9 KPA40487.1 - 1.2 8.8 9.1 61 3.2 8.9 2.8 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DASH_Spc19 PF08287.11 KPA40487.1 - 1.2 9.0 9.4 5 7.0 8.7 2.1 1 1 0 1 1 1 0 Spc19 ABC_tran_CTD PF16326.5 KPA40487.1 - 1.3 9.3 15.8 5.5 7.3 2.1 3.5 1 1 1 3 3 3 0 ABC transporter C-terminal domain DASH_Dam1 PF08653.10 KPA40487.1 - 1.5 8.7 7.2 18 5.2 0.1 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 Prominin PF05478.11 KPA40487.1 - 1.8 6.4 7.0 3 5.7 7.0 1.4 1 1 0 1 1 1 0 Prominin bZIP_1 PF00170.21 KPA40487.1 - 2.3 8.4 0.0 2.3 8.4 0.0 3.7 3 1 2 5 5 4 0 bZIP transcription factor ZapB PF06005.12 KPA40487.1 - 2.9 8.4 15.2 2 8.9 1.1 3.5 1 1 2 3 3 3 0 Cell division protein ZapB DUF4446 PF14584.6 KPA40487.1 - 4.6 7.2 8.7 3.1 7.8 2.0 2.6 1 1 3 4 4 4 0 Protein of unknown function (DUF4446) FadA PF09403.10 KPA40487.1 - 5.8 7.5 14.4 1.5 9.4 8.2 2.5 3 0 0 3 3 2 0 Adhesion protein FadA TMPIT PF07851.13 KPA40487.1 - 8.2 5.6 8.7 22 4.2 7.5 1.8 1 1 1 2 2 2 0 TMPIT-like protein Pyr_redox_2 PF07992.14 KPA40489.1 - 1.4e-42 145.9 0.1 2e-42 145.5 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA40489.1 - 5.8e-11 42.6 2.0 0.12 11.9 0.0 4.1 4 0 0 4 4 4 4 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA40489.1 - 3.8e-10 40.2 0.3 1.1e-06 29.1 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA40489.1 - 2e-06 27.9 2.8 0.3 11.1 0.0 3.8 3 1 1 4 4 4 3 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KPA40489.1 - 0.0015 17.8 0.6 15 4.7 0.0 3.8 2 2 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA40489.1 - 0.0016 17.6 2.3 0.74 8.8 0.1 3.5 3 1 1 4 4 4 2 Lycopene cyclase protein Trp_halogenase PF04820.14 KPA40489.1 - 0.0064 15.4 3.5 0.25 10.1 0.1 3.2 2 2 1 3 3 3 1 Tryptophan halogenase K_oxygenase PF13434.6 KPA40489.1 - 0.0095 15.1 0.7 0.016 14.4 0.0 1.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KPA40489.1 - 0.022 14.0 0.4 0.78 9.0 0.0 3.0 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KPA40489.1 - 0.042 12.6 1.1 2.5 6.7 0.0 3.3 4 0 0 4 4 4 0 HI0933-like protein YolD PF08863.10 KPA40489.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 YolD-like protein GIDA PF01134.22 KPA40489.1 - 0.068 12.2 3.8 3.1 6.8 0.2 3.8 4 0 0 4 4 4 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KPA40489.1 - 0.11 12.8 0.0 21 5.4 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Corona_nucleoca PF00937.18 KPA40490.1 - 0.03 13.3 2.0 0.071 12.1 2.0 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PhyH PF05721.13 KPA40491.1 - 1.1e-15 58.5 0.0 1.3e-15 58.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TPR_2 PF07719.17 KPA40492.1 - 3.3e-09 36.1 5.6 0.15 12.2 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KPA40492.1 - 1.9e-05 24.2 5.2 0.33 10.9 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KPA40492.1 - 4.5e-05 23.0 0.3 4.4 7.1 0.0 4.6 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.6 KPA40492.1 - 0.00048 20.4 8.9 3.2 8.1 1.4 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPA40492.1 - 0.0018 18.2 3.2 32 4.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KPA40492.1 - 0.0021 18.1 10.4 1.7 9.0 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KPA40492.1 - 0.022 15.3 7.3 8.1 7.0 0.3 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPA40492.1 - 0.63 10.8 4.3 56 4.8 1.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KPA40492.1 - 0.89 9.5 8.4 4.3 7.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat GFA PF04828.14 KPA40493.1 - 8.4e-25 86.9 0.1 1.3e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Sugar_tr PF00083.24 KPA40494.1 - 2.2e-40 138.9 18.6 8.9e-40 136.9 18.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA40494.1 - 1.9e-36 125.7 38.6 2.8e-33 115.3 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavi_NS4A PF01350.17 KPA40494.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Fungal_trans PF04082.18 KPA40495.1 - 1.1e-09 37.7 0.0 1.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA40495.1 - 6.1e-06 26.3 8.3 1.3e-05 25.3 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_2b PF00587.25 KPA40496.1 - 1.2e-34 119.8 0.0 1.9e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KPA40496.1 - 7.6e-17 61.5 4.7 1.8e-16 60.3 4.7 1.7 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Cytochrom_C552 PF02335.15 KPA40496.1 - 0.22 10.4 5.0 0.31 9.9 0.2 2.1 2 0 0 2 2 2 0 Cytochrome c552 DUF4139 PF13598.6 KPA40497.1 - 1.4e-31 109.8 1.0 1.4e-31 109.8 1.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KPA40497.1 - 1.9e-24 85.9 0.0 1.9e-24 85.9 0.0 3.8 3 0 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) DUF4746 PF15928.5 KPA40497.1 - 0.0094 15.4 1.3 0.0094 15.4 1.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4746) Methyltransf_10 PF05971.12 KPA40500.1 - 8.1e-52 176.4 0.1 2.8e-51 174.7 0.1 1.7 1 1 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KPA40500.1 - 0.00016 21.2 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KPA40500.1 - 0.0005 19.6 0.0 0.0013 18.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KPA40500.1 - 0.0013 18.7 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KPA40500.1 - 0.0056 16.4 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 KPA40500.1 - 0.013 16.2 0.0 0.97 10.1 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40500.1 - 0.023 15.4 0.0 0.11 13.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KPA40500.1 - 0.071 12.9 0.0 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain TrmK PF04816.12 KPA40500.1 - 0.15 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase PhyH PF05721.13 KPA40501.1 - 1.6e-20 74.3 0.0 2.4e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aldedh PF00171.22 KPA40502.1 - 7.6e-164 545.6 0.6 8.7e-164 545.4 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 KPA40503.1 - 1.1e-164 548.4 0.3 1.3e-164 548.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.32 KPA40505.1 - 2.9e-12 46.9 6.7 0.0015 19.3 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA40505.1 - 0.0058 16.9 1.5 2.5 8.4 0.0 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 KPA40506.1 - 8.3e-10 38.0 1.1 3.7e-09 35.9 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA40506.1 - 1.1e-05 25.5 10.6 1.1e-05 25.5 10.6 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.17 KPA40507.1 - 2.6e-07 30.2 0.6 0.0067 16.5 0.2 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KPA40507.1 - 1.8e-05 24.9 0.5 8.3e-05 22.8 0.4 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KPA40507.1 - 4.2e-05 23.2 1.0 0.38 10.7 0.5 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KPA40507.1 - 0.0075 15.9 2.0 0.023 14.4 0.6 2.3 2 1 0 2 2 2 1 TPR repeat Coatomer_E PF04733.14 KPA40507.1 - 0.012 15.1 0.9 0.016 14.6 0.9 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_19 PF14559.6 KPA40507.1 - 0.017 15.6 0.3 0.07 13.6 0.3 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPA40507.1 - 0.032 14.9 0.2 0.15 12.7 0.2 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA40507.1 - 0.041 14.1 1.8 0.11 12.7 1.8 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KPA40507.1 - 0.08 13.8 1.5 7.6 7.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat BID PF06393.11 KPA40507.1 - 1.4 8.4 5.1 0.12 12.0 0.5 1.5 2 0 0 2 2 2 0 BH3 interacting domain (BID) HAD_2 PF13419.6 KPA40508.1 - 1.1e-14 54.9 0.0 1.3e-07 31.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA40508.1 - 4.4e-07 30.4 0.0 3e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA40508.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like MFS_1 PF07690.16 KPA40509.1 - 3.3e-43 148.0 47.5 3.3e-43 148.0 47.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA40509.1 - 7.9e-06 25.0 13.2 7.9e-06 25.0 13.2 2.9 2 2 0 2 2 2 2 Sugar (and other) transporter Pantoate_ligase PF02569.15 KPA40510.1 - 2.6e-91 305.5 0.0 3.1e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Acyltransferase PF01553.21 KPA40511.1 - 2e-17 63.1 0.0 3.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.16 KPA40512.1 - 2.1e-29 101.3 0.4 3.5e-29 100.5 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 GYF PF02213.16 KPA40513.1 - 5.5e-19 67.6 0.3 1.4e-18 66.3 0.3 1.8 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KPA40513.1 - 0.0051 16.6 0.1 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 GYF domain 2 Serglycin PF04360.12 KPA40513.1 - 0.092 12.7 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Serglycin AAA_16 PF13191.6 KPA40514.1 - 1.4e-08 35.3 0.0 8.9e-07 29.4 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KPA40514.1 - 7.3e-07 29.2 0.1 1.6e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 KPA40514.1 - 0.0017 18.9 0.2 0.0074 16.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 KPA40514.1 - 0.0022 18.4 0.2 0.014 15.8 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 KPA40514.1 - 0.0042 17.6 0.1 0.016 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPA40514.1 - 0.0088 16.3 0.0 0.035 14.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KPA40514.1 - 0.013 15.6 0.0 0.038 14.1 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KPA40514.1 - 0.016 14.9 0.2 0.035 13.8 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KPA40514.1 - 0.018 15.5 0.0 0.1 13.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KPA40514.1 - 0.02 14.7 1.8 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KPA40514.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 KPA40514.1 - 0.031 14.3 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase1 PF18748.1 KPA40514.1 - 0.032 13.8 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 Viral_helicase1 PF01443.18 KPA40514.1 - 0.034 13.9 0.1 0.091 12.5 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KPA40514.1 - 0.036 13.8 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KPA40514.1 - 0.041 13.7 0.4 0.47 10.3 0.0 2.7 3 0 0 3 3 3 0 Deoxynucleoside kinase NB-ARC PF00931.22 KPA40514.1 - 0.051 12.8 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 KPA40514.1 - 0.065 13.2 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 KPA40514.1 - 0.065 13.4 4.5 0.27 11.4 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KPA40514.1 - 0.11 12.5 0.9 0.83 9.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KPA40514.1 - 0.35 10.9 3.5 3.6 7.6 0.0 2.8 4 0 0 4 4 3 0 Helicase HerA, central domain PIN_8 PF18476.1 KPA40514.1 - 0.45 10.3 3.5 1.2 9.0 3.5 1.7 1 1 0 1 1 1 0 PIN like domain OmdA PF13376.6 KPA40516.1 - 4.6e-22 77.8 0.9 2.8e-21 75.3 0.4 2.2 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated Zn_clus PF00172.18 KPA40517.1 - 3.4e-06 27.1 12.9 5.7e-06 26.3 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA40517.1 - 0.00044 19.2 1.1 0.00094 18.1 0.7 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain SseB_C PF14581.6 KPA40517.1 - 0.07 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 SseB protein C-terminal domain RGS PF00615.19 KPA40518.1 - 2.5e-05 24.5 0.0 8.5e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.25 KPA40520.1 - 2e-21 76.6 0.0 3.6e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40520.1 - 4e-21 75.5 0.0 8.9e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KPA40520.1 - 6.6e-18 65.1 0.6 1.7e-10 41.4 0.0 6.2 6 1 1 7 7 7 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA40520.1 - 3.2e-15 56.3 1.4 0.00018 22.0 0.2 6.6 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA40520.1 - 1.1e-12 46.9 3.1 0.05 14.2 0.2 7.2 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KPA40520.1 - 3.4e-11 43.1 8.5 0.00069 19.9 0.1 7.3 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 KPA40520.1 - 7.3e-08 32.5 0.4 0.00021 21.5 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeats (many copies) GFA PF04828.14 KPA40521.1 - 6.3e-20 71.3 0.1 9.5e-20 70.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Macro PF01661.21 KPA40524.1 - 1.9e-26 92.4 0.0 3.7e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Macro domain TatC PF00902.18 KPA40525.1 - 0.43 10.4 11.2 0.07 13.0 6.1 2.2 2 1 0 2 2 2 0 Sec-independent protein translocase protein (TatC) Fig1 PF12351.8 KPA40525.1 - 0.51 10.2 6.6 0.19 11.7 2.1 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 ApbA_C PF08546.11 KPA40527.1 - 9.1e-24 84.0 0.0 1.6e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KPA40527.1 - 3.3e-15 56.0 0.0 7.6e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Condensation PF00668.20 KPA40528.1 - 1.7e-137 458.8 0.0 2.1e-82 277.3 0.0 3.4 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 KPA40528.1 - 1.2e-133 445.9 0.0 1.1e-70 238.4 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KPA40528.1 - 4.3e-35 119.9 1.5 7.8e-10 39.0 0.1 4.5 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KPA40528.1 - 2.2e-08 34.9 0.0 0.023 15.7 0.0 3.9 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.6 KPA40528.1 - 3.4e-05 24.5 0.0 0.00026 21.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA40528.1 - 0.00012 22.0 0.3 0.00077 19.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA40528.1 - 0.00018 22.1 0.0 0.00077 20.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA40528.1 - 0.0052 17.5 0.0 0.015 16.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 KPA40529.1 - 4.8e-09 36.1 0.0 1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA40529.1 - 0.00014 21.8 0.1 0.00024 21.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPA40529.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase IMS PF00817.20 KPA40530.1 - 6.7e-41 139.8 0.0 1.1e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KPA40530.1 - 3.6e-11 43.8 0.0 9.1e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KPA40530.1 - 1.5e-10 40.5 1.4 3.3e-10 39.4 1.4 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KPA40530.1 - 0.0086 16.4 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DHHC PF01529.20 KPA40531.1 - 4.8e-22 78.5 2.4 4.8e-22 78.5 2.4 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4287 PF14117.6 KPA40531.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4287) SET PF00856.28 KPA40532.1 - 1.2e-15 58.3 0.8 6e-15 56.0 0.8 2.2 1 1 0 1 1 1 1 SET domain AWS PF17907.1 KPA40532.1 - 1.9e-07 31.0 7.1 5.7e-07 29.5 7.1 1.8 1 0 0 1 1 1 1 AWS domain CRAL_TRIO PF00650.20 KPA40533.1 - 2.9e-14 53.1 0.0 4.2e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KPA40533.1 - 1e-05 25.6 0.0 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ARPC4 PF05856.12 KPA40535.1 - 4.8e-80 267.0 4.2 5.3e-80 266.9 4.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 KPA40536.1 - 1.9e-48 165.2 0.0 2.5e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPA40536.1 - 7.5e-14 52.0 1.0 3e-13 50.0 1.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KPA40536.1 - 2.7e-12 46.3 0.1 6.4e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 KPA40536.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain CM_2 PF01817.21 KPA40537.1 - 0.0016 18.7 0.7 0.0027 18.0 0.7 1.4 1 0 0 1 1 1 1 Chorismate mutase type II DUF1465 PF07323.12 KPA40537.1 - 0.0072 16.2 0.4 0.0082 16.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) His_Phos_1 PF00300.22 KPA40538.1 - 1.8e-38 132.2 0.3 3.1e-36 124.9 0.3 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Methyltransf_23 PF13489.6 KPA40539.1 - 4.1e-13 49.5 0.0 6.7e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA40539.1 - 2.5e-10 40.1 0.0 4.2e-08 32.8 0.0 2.1 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KPA40539.1 - 3.5e-09 36.6 0.0 5.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40539.1 - 2.7e-08 34.4 0.6 1e-07 32.5 0.4 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA40539.1 - 1.6e-07 31.8 0.1 4.8e-07 30.3 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA40539.1 - 2.8e-06 28.0 0.0 6.2e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KPA40539.1 - 0.063 13.3 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KPA40540.1 - 4.7e-08 33.0 7.8 7e-08 32.5 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KPA40541.1 - 0.009 15.9 0.5 0.035 14.0 0.1 2.3 2 0 0 2 2 2 1 F-box-like DUF3463 PF11946.8 KPA40541.1 - 0.22 11.3 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) F-box PF00646.33 KPA40541.1 - 5.1 7.1 7.6 0.75 9.7 1.9 2.5 2 0 0 2 2 2 0 F-box domain GAT PF03127.14 KPA40542.1 - 6.7e-19 68.0 0.6 2.2e-18 66.3 0.2 2.1 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 KPA40542.1 - 5.1e-06 26.4 0.0 1.3e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 VHS domain HEAT_2 PF13646.6 KPA40542.1 - 0.0037 17.6 0.0 0.0095 16.3 0.0 1.7 1 0 0 1 1 1 1 HEAT repeats Macoilin PF09726.9 KPA40542.1 - 0.49 8.9 2.4 0.64 8.5 2.4 1.2 1 0 0 1 1 1 0 Macoilin family BAH PF01426.18 KPA40543.1 - 2.5e-06 27.4 0.2 4.4e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 BAH domain PLA1 PF02253.15 KPA40543.1 - 0.0033 17.1 1.3 0.0049 16.5 1.3 1.2 1 0 0 1 1 1 1 Phospholipase A1 PHD PF00628.29 KPA40543.1 - 0.017 15.0 3.2 0.017 15.0 3.2 1.9 2 0 0 2 2 2 0 PHD-finger F_actin_cap_B PF01115.17 KPA40544.1 - 6.7e-105 350.0 0.0 7.7e-105 349.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Epimerase PF01370.21 KPA40545.1 - 2.6e-17 63.1 0.0 3.3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KPA40545.1 - 6.5e-09 35.3 0.0 8.5e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KPA40545.1 - 0.0021 17.5 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPA40545.1 - 0.0075 15.3 0.0 0.079 11.9 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.23 KPA40545.1 - 0.091 12.9 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain CBS PF00571.28 KPA40547.1 - 1.9e-05 25.0 0.0 0.96 9.9 0.0 3.3 2 1 0 2 2 2 2 CBS domain DUF4165 PF13752.6 KPA40547.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) Mito_carr PF00153.27 KPA40548.1 - 7.9e-47 157.1 7.1 1.4e-18 66.6 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UCH PF00443.29 KPA40549.1 - 2.3e-53 181.4 0.0 2.3e-53 181.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPA40549.1 - 8.6e-24 84.7 10.0 1.1e-19 71.2 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF4407 PF14362.6 KPA40549.1 - 1.6 8.0 12.8 2.9 7.2 12.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Yos1 PF08571.10 KPA40550.1 - 5.6e-35 119.5 0.3 6.2e-35 119.3 0.3 1.0 1 0 0 1 1 1 1 Yos1-like DUF997 PF06196.12 KPA40550.1 - 0.1 12.6 2.4 4.8 7.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Glyco_transf_22 PF03901.17 KPA40551.1 - 6.6e-39 134.3 20.2 8.2e-39 134.0 20.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PP2C PF00481.21 KPA40552.1 - 1.8e-57 194.9 0.0 3.2e-57 194.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KPA40552.1 - 5.3e-44 147.8 49.4 1.4e-09 37.6 0.2 8.7 5 2 1 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KPA40552.1 - 2.3e-36 123.2 60.0 0.00034 20.9 0.2 11.4 9 2 1 11 11 11 9 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KPA40552.1 - 2.9e-30 105.3 0.0 1.4e-29 103.0 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 KPA40552.1 - 1.2e-23 82.5 5.0 3.6e-23 81.0 5.0 1.9 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.6 KPA40552.1 - 6.5e-07 29.0 17.5 0.053 13.0 0.7 4.4 3 1 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KPA40552.1 - 0.00014 22.0 43.3 9.9 7.2 1.2 15.7 18 1 0 18 18 18 1 Leucine Rich Repeat LRR_6 PF13516.6 KPA40552.1 - 0.0017 18.2 35.3 3.6 7.9 0.3 11.2 12 0 0 12 12 12 3 Leucine Rich repeat Alpha-amylase PF00128.24 KPA40553.1 - 2e-117 392.5 0.7 3.2e-117 391.8 0.7 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KPA40553.1 - 5e-08 32.9 0.0 9.6e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KPA40553.1 - 0.0044 16.2 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_42C PF08533.10 KPA40553.1 - 0.024 14.3 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Proteasome PF00227.26 KPA40554.1 - 2.3e-40 138.1 0.0 2.8e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 KPA40555.1 - 3.6e-24 84.8 0.0 1.1e-23 83.2 0.0 1.8 2 0 0 2 2 2 1 TUG ubiquitin-like domain DUF4294 PF14127.6 KPA40555.1 - 0.00013 22.0 0.1 0.00024 21.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4294) UBX PF00789.20 KPA40555.1 - 0.017 15.3 0.0 0.27 11.5 0.0 2.7 3 0 0 3 3 3 0 UBX domain RBD PF02196.15 KPA40555.1 - 0.018 15.1 0.1 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Raf-like Ras-binding domain Spore_III_AF PF09581.10 KPA40555.1 - 0.071 13.1 2.7 0.08 13.0 0.8 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) ECM1 PF05782.11 KPA40555.1 - 0.084 11.8 3.8 0.13 11.2 3.8 1.2 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) FERM_N PF09379.10 KPA40555.1 - 0.095 12.7 0.0 5.7 7.0 0.0 2.6 2 0 0 2 2 2 0 FERM N-terminal domain PAPA-1 PF04795.12 KPA40555.1 - 3.7 8.4 7.8 5.9 7.8 1.7 2.8 2 0 0 2 2 2 0 PAPA-1-like conserved region Ribosomal_L36e PF01158.18 KPA40556.1 - 1.1e-42 144.2 5.9 1.2e-42 144.1 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 KPA40556.1 - 0.0013 18.8 1.4 0.0016 18.6 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 PBS_linker_poly PF00427.21 KPA40556.1 - 0.033 14.2 0.2 0.037 14.1 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Lipase_3 PF01764.25 KPA40558.1 - 5.3e-30 104.2 0.0 7.1e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KPA40558.1 - 0.00023 21.8 0.1 0.00033 21.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA40558.1 - 0.0087 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KPA40558.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 KPA40558.1 - 0.036 13.6 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) 14-3-3 PF00244.20 KPA40559.1 - 2.1e-107 357.7 0.7 2.5e-107 357.5 0.7 1.0 1 0 0 1 1 1 1 14-3-3 protein MitMem_reg PF13012.6 KPA40559.1 - 0.075 13.5 0.2 0.64 10.5 0.0 2.3 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Syja_N PF02383.18 KPA40561.1 - 2.3e-72 244.0 0.0 4.7e-72 243.0 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 KPA40561.1 - 9.6e-11 41.6 0.1 1.8e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NRDE-2 PF08424.10 KPA40562.1 - 0.0051 16.0 0.4 0.51 9.4 0.4 2.8 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KPA40563.1 - 4.4e-05 23.9 6.8 0.01 16.6 0.4 4.8 3 1 2 5 5 5 2 Tetratricopeptide repeat Suf PF05843.14 KPA40563.1 - 0.034 14.1 5.4 5.1 7.0 0.0 3.7 4 1 0 5 5 5 0 Suppressor of forked protein (Suf) TPR_7 PF13176.6 KPA40563.1 - 0.077 13.1 0.3 3.3 8.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3022 PF11226.8 KPA40563.1 - 0.085 13.3 0.2 0.79 10.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3022) peroxidase PF00141.23 KPA40564.1 - 7.9e-47 159.9 0.0 1.3e-46 159.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase IBR PF01485.21 KPA40565.1 - 5.6e-14 52.1 31.7 2.1e-07 31.0 6.0 3.6 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KPA40565.1 - 0.0007 19.5 8.1 0.0007 19.5 8.1 3.4 3 0 0 3 3 3 1 zinc-RING finger domain FYVE PF01363.21 KPA40565.1 - 0.0035 17.4 5.0 0.0035 17.4 5.0 3.5 2 1 1 3 3 3 1 FYVE zinc finger ATP-synt_E_2 PF08112.11 KPA40565.1 - 0.043 14.1 0.2 0.13 12.6 0.2 1.8 1 0 0 1 1 1 0 ATP synthase epsilon subunit Glyco_hydro_77 PF02446.17 KPA40565.1 - 2.2 7.1 14.4 3.7 6.3 0.6 2.1 2 0 0 2 2 2 0 4-alpha-glucanotransferase RhoGAP PF00620.27 KPA40566.1 - 2.7e-49 166.9 0.0 5.6e-49 165.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KPA40566.1 - 9.7e-13 48.2 0.2 2.7e-12 46.8 0.2 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF5321 PF17254.2 KPA40566.1 - 0.0045 16.4 0.9 0.0077 15.7 0.9 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5321) BBP1_C PF15272.6 KPA40566.1 - 0.049 13.5 1.6 0.095 12.5 1.6 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Acetyltransf_11 PF13720.6 KPA40566.1 - 0.054 14.0 0.2 0.72 10.4 0.0 2.9 3 1 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TPR_MLP1_2 PF07926.12 KPA40566.1 - 3.7 7.6 12.6 0.25 11.4 5.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Med12 PF09497.10 KPA40567.1 - 5.7e-28 97.0 0.4 1.4e-27 95.7 0.4 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 KPA40567.1 - 0.0069 15.3 0.0 0.19 10.5 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain Pyrid_oxidase_2 PF13883.6 KPA40568.1 - 1.8e-41 141.9 0.0 2.6e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.25 KPA40569.1 - 1.8e-59 201.3 0.0 1.6e-58 198.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40569.1 - 2.6e-28 99.0 0.2 1.2e-19 70.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KPA40569.1 - 4.3e-05 24.1 1.4 4.3e-05 24.1 1.4 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KPA40569.1 - 0.011 15.0 0.3 0.056 12.8 0.0 2.1 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 KPA40569.1 - 0.013 15.4 4.2 0.22 11.4 0.1 3.5 3 1 1 4 4 4 0 Phosphotransferase enzyme family Kdo PF06293.14 KPA40569.1 - 0.034 13.5 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KPA40569.1 - 0.051 12.5 0.0 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain GATA PF00320.27 KPA40570.1 - 1.9e-16 59.4 2.3 3.6e-16 58.5 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KPA40570.1 - 7.3e-11 41.7 0.1 1.6e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CYYR1 PF10873.8 KPA40571.1 - 0.75 10.2 0.0 0.75 10.2 0.0 4.0 4 0 0 4 4 4 0 Cysteine and tyrosine-rich protein 1 Abhydrolase_9 PF10081.9 KPA40572.1 - 0.031 13.4 0.1 0.049 12.7 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Pkinase PF00069.25 KPA40573.1 - 8.7e-58 195.7 0.0 1.1e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40573.1 - 3.3e-31 108.5 0.0 4.3e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA40573.1 - 0.0022 17.4 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KPA40573.1 - 0.0042 16.5 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KPA40573.1 - 0.0084 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KPA40573.1 - 0.023 14.6 0.2 0.023 14.6 0.2 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family EspF PF04806.12 KPA40573.1 - 0.034 14.5 1.6 0.034 14.5 1.6 2.2 2 0 0 2 2 2 0 EspF protein repeat Presenilin PF01080.17 KPA40574.1 - 9.6 4.8 6.3 11 4.7 6.3 1.0 1 0 0 1 1 1 0 Presenilin zf-RING_2 PF13639.6 KPA40575.1 - 2.7e-09 37.2 4.8 3.9e-09 36.7 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KPA40575.1 - 5.2e-07 29.8 4.7 1.5e-06 28.3 4.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KPA40575.1 - 0.00089 19.3 3.8 0.0029 17.6 3.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KPA40575.1 - 0.00097 18.9 3.8 0.0024 17.7 3.8 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA40575.1 - 0.0011 18.8 5.4 0.0031 17.3 5.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KPA40575.1 - 0.007 16.1 1.4 0.033 14.0 0.3 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 KPA40575.1 - 0.021 14.9 0.6 0.021 14.9 0.6 1.6 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 KPA40575.1 - 0.054 13.4 3.8 0.095 12.6 3.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPA40575.1 - 0.14 12.1 2.8 0.31 11.0 2.9 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 KPA40575.1 - 0.59 9.9 5.3 0.32 10.8 2.4 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KPA40575.1 - 1 9.5 5.2 0.71 9.9 3.2 1.8 1 1 0 1 1 1 0 RING-type zinc-finger Epimerase PF01370.21 KPA40576.1 - 6e-09 35.7 0.0 8.7e-09 35.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPA40576.1 - 2e-07 31.1 0.0 3.2e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 KPA40576.1 - 1.1e-05 25.0 0.0 0.00012 21.7 0.0 2.0 1 1 1 2 2 2 1 HIM1 NmrA PF05368.13 KPA40576.1 - 0.0037 16.9 0.0 0.008 15.7 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family DUF3712 PF12505.8 KPA40576.1 - 0.019 15.2 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3712) Semialdhyde_dh PF01118.24 KPA40576.1 - 0.054 13.9 0.1 0.15 12.5 0.1 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Flavokinase PF01687.17 KPA40577.1 - 6.1e-36 123.1 0.0 1.8e-35 121.6 0.0 1.6 2 0 0 2 2 2 1 Riboflavin kinase YTH PF04146.15 KPA40577.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 YT521-B-like domain PAS PF00989.25 KPA40578.1 - 0.00095 19.2 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 KPA40578.1 - 0.0061 16.7 8.8 0.0061 16.7 8.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPA40579.1 - 1.2e-20 73.8 25.7 1.6e-15 56.9 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA40579.1 - 1.7e-06 27.2 9.3 1.6e-05 24.0 0.6 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPA40579.1 - 0.48 8.8 6.8 0.12 10.8 2.4 2.1 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ThiF PF00899.21 KPA40581.1 - 3.4e-42 144.5 0.0 5.2e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KPA40581.1 - 9.8e-05 22.6 0.0 0.00033 20.9 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KPA40581.1 - 0.0043 17.5 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 KPA40581.1 - 0.011 16.0 0.3 0.033 14.4 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KPA40581.1 - 0.026 14.1 0.2 0.051 13.2 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Melibiase_2 PF16499.5 KPA40581.1 - 0.037 13.2 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A TPR_14 PF13428.6 KPA40582.1 - 0.11 13.4 1.8 4.2 8.4 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PaO PF08417.12 KPA40582.1 - 0.15 12.2 0.3 0.7 10.1 0.1 2.1 2 0 0 2 2 2 0 Pheophorbide a oxygenase Atg29_N PF18388.1 KPA40583.1 - 8.8e-26 89.5 2.0 2e-25 88.4 2.0 1.6 1 0 0 1 1 1 1 Atg29 N-terminal domain Thioredox_DsbH PF03190.15 KPA40585.1 - 5.2e-58 195.6 0.0 1e-57 194.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KPA40585.1 - 1.9e-05 24.7 0.0 5.9e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like DUF883 PF05957.13 KPA40585.1 - 0.068 13.8 2.6 48 4.6 0.3 4.1 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Thioredoxin_2 PF13098.6 KPA40585.1 - 0.16 12.4 0.0 0.57 10.7 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like domain DLIC PF05783.11 KPA40586.1 - 9e-31 107.2 0.0 2.8e-29 102.3 0.0 2.2 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 KPA40587.1 - 1.5e-13 50.3 0.0 3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPA40587.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif WD40 PF00400.32 KPA40588.1 - 4.1e-07 30.6 0.2 0.097 13.6 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA40588.1 - 0.0011 19.2 0.0 0.19 12.0 0.0 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KPA40588.1 - 0.0059 14.7 0.0 0.0083 14.2 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Gmad1 PF10647.9 KPA40588.1 - 0.018 14.8 0.2 13 5.5 0.0 3.0 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 KPA40588.1 - 0.077 11.9 0.1 1.1 8.1 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Septin PF00735.18 KPA40589.1 - 7.8e-107 356.7 0.0 1.4e-106 355.9 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KPA40589.1 - 0.00013 22.0 0.0 0.00034 20.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KPA40589.1 - 0.0083 16.2 4.4 2.2 8.3 0.0 3.1 2 1 0 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KPA40589.1 - 0.0094 15.9 0.6 0.0094 15.9 0.6 2.1 2 1 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KPA40589.1 - 0.06 13.5 0.5 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KPA40589.1 - 0.066 12.7 0.1 0.4 10.2 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain IIGP PF05049.13 KPA40589.1 - 0.068 12.2 0.0 0.16 11.0 0.1 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 KPA40589.1 - 0.1 11.9 0.2 0.21 10.9 0.2 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family EB1 PF03271.17 KPA40589.1 - 0.12 12.6 2.3 3.5 7.9 1.3 2.7 2 0 0 2 2 2 0 EB1-like C-terminal motif AAA_22 PF13401.6 KPA40589.1 - 0.14 12.4 2.1 0.27 11.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KPA40589.1 - 0.72 10.3 5.2 20 5.6 4.7 2.2 2 0 0 2 2 2 0 AAA domain Bax1-I PF01027.20 KPA40590.1 - 1.3e-52 178.6 25.9 1.5e-52 178.4 25.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4407 PF14362.6 KPA40590.1 - 3.2 7.0 13.6 2.3 7.5 5.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TRAM_LAG1_CLN8 PF03798.16 KPA40591.1 - 4.8e-48 163.5 19.9 7.6e-48 162.9 18.4 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KPA40591.1 - 8e-22 76.7 0.1 2.3e-21 75.2 0.1 1.9 1 0 0 1 1 1 1 TRAM1-like protein DUF5585 PF17823.1 KPA40591.1 - 0.21 10.5 4.3 0.28 10.1 4.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) AMP-binding PF00501.28 KPA40592.1 - 4e-90 302.4 0.0 5e-90 302.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA40592.1 - 4e-18 66.2 0.1 1.4e-17 64.4 0.1 2.0 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain UBA_3 PF09288.10 KPA40592.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Gly_transf_sug PF04488.15 KPA40593.1 - 1e-13 51.7 0.0 2.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3237 PF11578.8 KPA40594.1 - 5.4e-23 81.5 0.0 7.8e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) OST-HTH PF12872.7 KPA40594.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Rpp20 PF12328.8 KPA40595.1 - 1.4e-28 99.6 0.2 2e-28 99.1 0.2 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KPA40595.1 - 1.8e-11 43.7 0.1 3.1e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Alba DUF2625 PF10946.8 KPA40595.1 - 0.15 11.1 0.2 0.23 10.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2625 Rogdi_lz PF10259.9 KPA40596.1 - 3.7e-92 308.6 0.0 4.2e-92 308.4 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein NIPSNAP PF07978.13 KPA40597.1 - 2.6e-40 136.8 0.2 1.4e-28 99.1 0.0 2.4 2 0 0 2 2 2 2 NIPSNAP ATP-synt_J PF04911.12 KPA40598.1 - 5.8e-28 96.2 2.7 9.5e-28 95.5 2.7 1.4 1 0 0 1 1 1 1 ATP synthase j chain FSH1 PF03959.13 KPA40599.1 - 4.7e-59 199.6 0.0 5.7e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.9 KPA40599.1 - 0.00018 21.1 0.6 0.026 14.0 0.8 2.3 2 1 0 2 2 2 2 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KPA40599.1 - 0.00035 19.9 0.0 0.053 12.8 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA40599.1 - 0.00051 19.8 0.0 2.1 7.9 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KPA40599.1 - 0.0032 17.3 0.0 1.5 8.6 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.18 KPA40599.1 - 0.018 14.6 0.0 3.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.20 KPA40599.1 - 0.095 12.3 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Putative esterase DUF2974 PF11187.8 KPA40599.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AXE1 PF05448.12 KPA40599.1 - 0.2 10.3 0.1 0.31 9.7 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PCI PF01399.27 KPA40600.1 - 2.2e-22 79.5 0.1 1.5e-21 76.9 0.0 2.5 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KPA40600.1 - 4.7e-16 58.6 2.9 4.7e-16 58.6 2.9 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF4363 PF14276.6 KPA40600.1 - 0.17 12.0 6.7 3.9 7.6 0.4 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) Cas_DxTHG PF09455.10 KPA40600.1 - 1.9 8.0 8.9 0.46 10.0 5.3 1.8 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family DASH_Spc19 PF08287.11 KPA40601.1 - 3.7e-50 169.9 1.4 5.2e-50 169.4 1.4 1.2 1 0 0 1 1 1 1 Spc19 SH3_1 PF00018.28 KPA40602.1 - 4.9e-09 35.7 0.1 9.3e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPA40602.1 - 1e-06 28.5 0.1 3.1e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KPA40602.1 - 1.3e-05 24.8 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TMEM220 PF15071.6 KPA40602.1 - 0.08 13.7 2.1 0.18 12.6 2.1 1.6 1 0 0 1 1 1 0 Transmembrane family 220, helix Dynactin_p22 PF07426.11 KPA40603.1 - 8e-08 32.3 1.2 1.8e-06 27.9 0.0 2.0 1 1 1 2 2 2 1 Dynactin subunit p22 EMP24_GP25L PF01105.24 KPA40603.1 - 0.37 10.7 2.9 14 5.6 0.3 2.9 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD HalX PF08663.10 KPA40603.1 - 1.1 9.7 15.0 1.4 9.3 1.0 3.3 2 1 0 3 3 3 0 HalX domain DUF4140 PF13600.6 KPA40603.1 - 7.2 7.1 11.7 1.8 9.0 1.3 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Aa_trans PF01490.18 KPA40604.1 - 2.2e-94 316.5 19.4 3.2e-94 316.0 19.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.10 KPA40604.1 - 0.0026 16.1 1.3 0.0051 15.1 1.3 1.4 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Ribosomal_S16 PF00886.19 KPA40605.1 - 9.8e-26 89.6 0.1 1.6e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Sugar_tr PF00083.24 KPA40606.1 - 1.5e-85 287.8 22.9 1.8e-85 287.5 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA40606.1 - 4e-14 52.3 68.2 2.7e-13 49.6 35.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CrgA PF06781.12 KPA40606.1 - 0.44 10.6 5.5 0.54 10.4 0.0 3.5 4 0 0 4 4 4 0 Cell division protein CrgA HNH_2 PF13391.6 KPA40607.1 - 2.1e-06 27.8 0.1 4.6e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Peptidase_M14 PF00246.24 KPA40608.1 - 2e-16 60.7 0.0 3.1e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KPA40608.1 - 0.00013 21.2 0.0 0.00025 20.2 0.0 1.5 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family AA_permease_2 PF13520.6 KPA40609.1 - 6.1e-51 173.6 51.9 7.8e-51 173.2 51.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA40609.1 - 7.6e-22 77.6 42.1 1e-21 77.1 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease Asp4 PF16996.5 KPA40609.1 - 0.18 11.6 0.2 0.18 11.6 0.2 2.5 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 Smim3 PF17307.2 KPA40609.1 - 0.45 10.0 3.1 11 5.6 0.1 3.1 2 0 0 2 2 2 0 Small integral membrane protein 3 Epiglycanin_C PF14654.6 KPA40609.1 - 2 8.5 8.0 7 6.8 0.2 3.0 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region AgrD PF05931.11 KPA40609.1 - 4.1 7.5 5.2 0.87 9.7 0.2 2.4 2 0 0 2 2 2 0 Staphylococcal AgrD protein CBM_4_9 PF02018.17 KPA40610.1 - 0.0076 16.5 0.0 0.0088 16.3 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain Hydrolase_4 PF12146.8 KPA40611.1 - 2e-11 43.6 0.0 2.4e-10 40.1 0.0 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA40611.1 - 1.2e-08 35.9 1.2 1.9e-08 35.2 1.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA40611.1 - 9.3e-05 22.2 0.2 0.0019 17.9 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 KPA40611.1 - 0.00031 20.1 0.3 0.0056 16.1 0.3 2.1 1 1 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KPA40611.1 - 0.00043 19.8 0.8 0.39 10.1 0.5 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KPA40611.1 - 0.0011 18.5 0.2 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF2236 PF09995.9 KPA40612.1 - 5.3e-30 105.3 0.2 3.2e-29 102.8 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Terpene_synth_C PF03936.16 KPA40613.1 - 5.1e-07 29.3 0.0 7.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Fungal_trans PF04082.18 KPA40614.1 - 5.4e-11 42.0 1.4 8.4e-11 41.4 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Vert_IL3-reg_TF PF06529.11 KPA40614.1 - 0.069 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor Lipase_GDSL_2 PF13472.6 KPA40615.1 - 2.6e-11 44.2 0.0 3.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA40615.1 - 3.2e-05 24.0 0.2 4.2e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KPA40615.1 - 0.046 13.9 0.4 0.28 11.3 0.4 2.1 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family LPP PF04728.13 KPA40616.1 - 0.1 13.0 1.0 1.5 9.3 0.2 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DivIC PF04977.15 KPA40616.1 - 1.5 8.6 10.1 1.6 8.5 0.9 2.4 2 1 0 2 2 2 0 Septum formation initiator Phosphoesterase PF04185.14 KPA40620.1 - 5.1e-11 42.4 1.3 5.3e-10 39.0 0.2 2.0 1 1 1 2 2 2 2 Phosphoesterase family Peptidase_M14 PF00246.24 KPA40621.1 - 5.9e-13 49.3 0.0 8.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KPA40621.1 - 0.0034 16.5 0.0 0.014 14.4 0.0 2.0 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family Fungal_trans PF04082.18 KPA40622.1 - 1.4e-14 53.8 0.0 2.3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rpn9_C PF18261.1 KPA40622.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Rpn9 C-terminal helix Sulfatase PF00884.23 KPA40623.1 - 1.6e-62 211.6 0.0 2.1e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KPA40623.1 - 1.4e-08 35.5 0.0 2.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KPA40623.1 - 4.2e-05 23.3 0.0 0.0027 17.4 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 KPA40624.1 - 1.2e-28 100.1 25.0 1.2e-28 100.1 25.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily RNA_pol_Rpb8 PF03870.15 KPA40624.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb8 Bombesin PF02044.17 KPA40626.1 - 0.13 12.4 0.2 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Bombesin-like peptide Sulfate_transp PF00916.20 KPA40627.1 - 1.9e-87 293.5 12.8 2.4e-87 293.2 12.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KPA40627.1 - 1e-07 31.6 0.0 1.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain MotB_plug PF13677.6 KPA40627.1 - 0.0053 16.3 0.4 0.012 15.2 0.4 1.5 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB STAS_2 PF13466.6 KPA40627.1 - 0.13 12.6 0.0 4.6 7.7 0.0 2.8 2 0 0 2 2 2 0 STAS domain DUF1275 PF06912.11 KPA40628.1 - 2.9e-48 164.3 12.1 3.4e-48 164.1 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MgtC PF02308.16 KPA40628.1 - 0.67 10.3 5.8 0.59 10.5 2.0 2.4 2 1 0 2 2 2 0 MgtC family Cupin_1 PF00190.22 KPA40629.1 - 2.4e-40 137.6 0.0 1.2e-20 73.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KPA40629.1 - 2.9e-26 91.0 0.8 6.8e-13 48.1 0.2 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KPA40629.1 - 2.1e-08 33.7 0.1 0.00032 20.4 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KPA40629.1 - 1.1e-07 31.8 0.1 0.00035 20.5 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KPA40629.1 - 0.0063 16.4 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.14 KPA40629.1 - 0.011 15.9 0.6 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.12 KPA40629.1 - 0.032 13.9 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_7 PF12973.7 KPA40629.1 - 0.1 12.5 0.2 0.49 10.4 0.1 2.1 1 1 0 1 1 1 0 ChrR Cupin-like domain AA_permease_2 PF13520.6 KPA40630.1 - 9.3e-54 182.9 45.6 1.8e-53 181.9 45.5 1.5 1 1 0 1 1 1 1 Amino acid permease CE2_N PF17996.1 KPA40630.1 - 1.1e-19 70.4 0.0 2.6e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal AA_permease PF00324.21 KPA40630.1 - 1.5e-17 63.3 30.7 2.7e-17 62.6 30.7 1.3 1 0 0 1 1 1 1 Amino acid permease Lipase_GDSL_2 PF13472.6 KPA40630.1 - 1.4e-13 51.6 0.3 2.7e-13 50.7 0.3 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA40630.1 - 9.4e-07 29.0 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TB2_DP1_HVA22 PF03134.19 KPA40630.1 - 0.36 10.8 4.8 2.7 8.0 5.3 2.3 2 0 0 2 2 2 0 TB2/DP1, HVA22 family ER_lumen_recept PF00810.18 KPA40630.1 - 1.1 10.1 8.6 0.19 12.5 1.9 2.5 2 1 0 2 2 2 0 ER lumen protein retaining receptor Vma12 PF11712.8 KPA40631.1 - 0.23 11.5 1.1 0.39 10.8 1.1 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase MARVEL PF01284.23 KPA40631.1 - 2.1 8.3 11.6 0.064 13.3 4.8 2.0 2 1 0 2 2 2 0 Membrane-associating domain Methyltransf_23 PF13489.6 KPA40632.1 - 3.8e-25 88.6 0.0 5.9e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40632.1 - 8.9e-16 58.4 0.0 3.1e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA40632.1 - 1.9e-13 50.8 0.0 4.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA40632.1 - 2.1e-13 50.4 0.0 1.1e-11 44.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA40632.1 - 6.1e-10 39.7 0.0 2e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA40632.1 - 2.4e-07 30.3 0.0 2.2e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPA40632.1 - 5.3e-06 26.1 0.0 4.3e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KPA40632.1 - 0.0001 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KPA40632.1 - 0.00033 20.2 0.0 0.0017 17.8 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KPA40632.1 - 0.0037 17.4 0.0 0.0049 17.0 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KPA40632.1 - 0.075 12.3 0.0 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_16 PF10294.9 KPA40632.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 KPA40632.1 - 0.089 12.1 0.0 0.16 11.2 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase p450 PF00067.22 KPA40633.1 - 4.2e-23 81.8 0.0 5.4e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 KPA40634.1 - 2.6e-23 83.0 0.0 4.3e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_1_2 PF00155.21 KPA40635.1 - 3.1e-76 256.9 0.0 3.5e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II E1-E2_ATPase PF00122.20 KPA40638.1 - 2e-49 167.6 5.7 3.2e-49 166.9 1.5 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KPA40638.1 - 3.1e-45 154.1 4.6 3.1e-45 154.1 4.6 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KPA40638.1 - 6.9e-20 70.9 0.0 3.1e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KPA40638.1 - 5.2e-19 67.7 0.0 1.4e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KPA40638.1 - 1.6e-14 54.7 0.6 2.4e-13 50.9 0.2 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPA40638.1 - 0.0067 16.9 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RTC4 PF14474.6 KPA40639.1 - 4.2e-33 114.1 0.1 9.9e-33 112.9 0.1 1.7 1 0 0 1 1 1 1 RTC4-like domain EHN PF06441.12 KPA40639.1 - 0.059 13.7 0.1 0.23 11.8 0.1 2.0 1 0 0 1 1 1 0 Epoxide hydrolase N terminus ProRS-C_1 PF09180.11 KPA40639.1 - 0.059 13.6 0.2 0.16 12.2 0.2 1.7 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal LAP1C PF05609.12 KPA40639.1 - 3.3 6.7 20.9 6.3 5.8 20.9 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Dynamitin PF04912.14 KPA40640.1 - 5.1e-115 384.9 13.1 6.2e-115 384.6 13.1 1.1 1 0 0 1 1 1 1 Dynamitin TPR_MLP1_2 PF07926.12 KPA40640.1 - 0.00016 21.8 6.8 0.00016 21.8 6.8 3.3 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 KPA40640.1 - 0.0078 16.2 2.6 0.0078 16.2 2.6 3.8 3 1 1 4 4 4 1 Laminin Domain II Phage_GP20 PF06810.11 KPA40640.1 - 0.019 14.7 2.6 0.019 14.7 2.6 3.4 3 0 0 3 3 3 0 Phage minor structural protein GP20 DUF1192 PF06698.11 KPA40640.1 - 0.02 14.9 3.2 0.02 14.9 3.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) ATP-synt_E PF05680.12 KPA40640.1 - 0.029 14.7 0.8 0.029 14.7 0.8 3.2 3 0 0 3 3 3 0 ATP synthase E chain FH2 PF02181.23 KPA40640.1 - 0.043 12.9 10.4 0.27 10.3 0.7 2.8 3 0 0 3 3 3 0 Formin Homology 2 Domain Fib_alpha PF08702.10 KPA40640.1 - 0.054 13.7 9.1 2.5 8.3 0.9 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF4424 PF14415.6 KPA40640.1 - 0.058 12.6 0.2 0.13 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) DUF2408 PF10303.9 KPA40640.1 - 0.08 13.5 0.4 0.08 13.5 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) XhlA PF10779.9 KPA40640.1 - 0.081 13.1 0.8 0.081 13.1 0.8 4.6 3 2 1 4 4 4 0 Haemolysin XhlA DUF4140 PF13600.6 KPA40640.1 - 0.095 13.1 14.0 3.9 8.0 0.2 3.7 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Fzo_mitofusin PF04799.13 KPA40640.1 - 0.19 11.3 9.4 0.65 9.5 0.1 3.2 3 0 0 3 3 3 0 fzo-like conserved region DUF2046 PF09755.9 KPA40640.1 - 0.2 10.9 13.5 1.3 8.1 0.5 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Cytochrom_B562 PF07361.11 KPA40640.1 - 0.2 12.3 10.4 3.3 8.4 0.5 3.4 3 0 0 3 3 3 0 Cytochrome b562 ADIP PF11559.8 KPA40640.1 - 0.27 11.3 20.7 1.5 8.9 1.5 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding HWE_HK PF07536.14 KPA40640.1 - 0.27 12.0 8.4 0.19 12.5 0.9 3.7 4 0 0 4 4 3 0 HWE histidine kinase BLOC1_2 PF10046.9 KPA40640.1 - 0.3 11.4 13.3 2.4 8.5 1.7 3.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 KPA40640.1 - 0.33 11.7 15.7 4.2 8.1 0.7 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Spore_III_AB PF09548.10 KPA40640.1 - 0.37 10.9 6.3 0.31 11.1 0.2 2.8 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Snapin_Pallidin PF14712.6 KPA40640.1 - 0.62 10.5 12.6 6.4 7.3 0.8 4.2 2 1 2 4 4 4 0 Snapin/Pallidin Spc7 PF08317.11 KPA40640.1 - 0.69 8.7 23.4 1.4 7.7 13.9 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein Flagellin_N PF00669.20 KPA40640.1 - 0.72 10.0 12.1 0.14 12.2 1.1 3.5 3 1 1 4 4 4 0 Bacterial flagellin N-terminal helical region DivIC PF04977.15 KPA40640.1 - 0.78 9.6 18.8 2.3 8.0 2.4 3.6 3 0 0 3 3 3 0 Septum formation initiator DUF724 PF05266.14 KPA40640.1 - 0.83 9.4 13.9 0.32 10.8 1.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF724) ISG65-75 PF11727.8 KPA40640.1 - 1.4 8.1 14.7 1.6 7.9 1.6 3.1 3 0 0 3 3 3 0 Invariant surface glycoprotein KxDL PF10241.9 KPA40640.1 - 1.5 9.2 9.6 1.2 9.4 0.7 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein Cauli_AT PF03233.13 KPA40640.1 - 2.3 8.1 9.2 0.83 9.6 1.0 2.8 3 0 0 3 3 3 0 Aphid transmission protein DUF16 PF01519.16 KPA40640.1 - 2.8 8.5 11.4 16 6.0 0.3 3.5 3 1 0 3 3 3 0 Protein of unknown function DUF16 DUF4407 PF14362.6 KPA40640.1 - 3.9 6.7 18.7 1.8 7.9 1.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KPA40640.1 - 4.9 7.5 19.6 6 7.2 3.4 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) MRPL52 PF18699.1 KPA40640.1 - 5 7.4 14.4 0.22 11.7 1.0 3.4 3 0 0 3 3 3 0 Mitoribosomal protein mL52 DUF3450 PF11932.8 KPA40640.1 - 5.2 6.3 21.0 1.2 8.4 3.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) GrpE PF01025.19 KPA40640.1 - 6.2 6.5 19.5 0.16 11.6 1.7 3.8 2 1 1 4 4 4 0 GrpE YabA PF06156.13 KPA40640.1 - 7 7.3 12.8 3.5 8.3 0.3 3.3 3 0 0 3 3 3 0 Initiation control protein YabA Ribosomal_S28e PF01200.18 KPA40641.1 - 6.3e-28 96.6 2.0 7.3e-28 96.3 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e ThiS PF02597.20 KPA40642.1 - 8e-10 39.2 0.0 1.1e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 ThiS family Complex1_LYR PF05347.15 KPA40644.1 - 6.3e-17 61.4 3.1 7.3e-17 61.2 3.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KPA40644.1 - 2.7e-07 31.2 0.5 3.3e-07 31.0 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KPA40644.1 - 0.053 14.1 1.3 0.2 12.3 1.3 1.8 1 1 0 1 1 1 0 Complex1_LYR-like Dus PF01207.17 KPA40647.1 - 3.4e-37 128.2 0.0 4.8e-33 114.6 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Sec10 PF07393.11 KPA40648.1 - 2.3e-222 740.4 10.4 2.6e-222 740.2 10.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Phage_TAC_3 PF06896.11 KPA40648.1 - 0.034 14.7 0.2 0.034 14.7 0.2 3.7 4 0 0 4 4 4 0 Phage tail assembly chaperone proteins, TAC Prenyltransf PF01255.19 KPA40649.1 - 3.8e-05 23.3 0.0 0.0007 19.2 0.0 2.1 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase CBP_GIL PF10995.8 KPA40649.1 - 0.17 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis GIL 2OG-FeII_Oxy_2 PF13532.6 KPA40650.1 - 4.3e-28 98.8 0.0 8.9e-28 97.8 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FTO_NTD PF12933.7 KPA40650.1 - 0.2 10.9 0.0 1 8.5 0.0 1.9 1 1 1 2 2 2 0 FTO catalytic domain Met_10 PF02475.16 KPA40651.1 - 2.7e-71 239.4 0.0 3.6e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein DUF1752 PF08550.10 KPA40652.1 - 1.2e-11 44.2 2.9 2.5e-11 43.2 2.9 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RNB PF00773.19 KPA40653.1 - 1.3e-51 175.9 0.0 1.9e-51 175.4 0.0 1.2 1 0 0 1 1 1 1 RNB domain Cytochrom_D1 PF02239.16 KPA40655.1 - 0.027 13.0 0.0 0.061 11.8 0.0 1.5 1 1 1 2 2 2 0 Cytochrome D1 heme domain WD40 PF00400.32 KPA40655.1 - 0.029 15.2 1.6 0.29 12.1 1.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat tRNA-synt_2b PF00587.25 KPA40656.1 - 1.1e-30 106.9 0.0 2.8e-29 102.4 0.0 2.7 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KPA40656.1 - 4e-18 65.3 0.4 7.9e-18 64.4 0.4 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KPA40656.1 - 1.8e-12 47.1 0.0 4.3e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KPA40656.1 - 7.3e-10 38.8 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain KxDL PF10241.9 KPA40656.1 - 0.023 15.0 0.1 0.082 13.2 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein Thioredoxin PF00085.20 KPA40658.1 - 1.2e-63 211.5 6.4 6.2e-31 106.4 0.1 4.1 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KPA40658.1 - 1.1e-47 162.4 2.6 1.5e-36 126.0 0.7 3.9 2 2 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KPA40658.1 - 7.4e-10 38.9 1.2 0.00012 22.1 0.0 3.0 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KPA40658.1 - 3.5e-09 36.9 0.0 0.0092 16.3 0.0 4.0 3 1 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 KPA40658.1 - 3e-08 33.4 0.9 0.0022 17.4 0.0 3.4 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 KPA40658.1 - 1.6e-07 30.7 0.7 1.6e-07 30.7 0.7 2.1 1 1 1 2 2 2 1 Calsequestrin AhpC-TSA PF00578.21 KPA40658.1 - 3.4e-07 30.2 0.3 0.049 13.5 0.0 3.0 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_2 PF13098.6 KPA40658.1 - 9.5e-07 29.2 1.3 0.035 14.6 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.10 KPA40658.1 - 4.5e-06 26.4 1.9 0.0099 15.6 0.0 3.4 3 0 0 3 3 3 2 Redoxin ERp29_N PF07912.13 KPA40658.1 - 0.0027 17.9 0.5 2 8.6 0.0 3.6 3 1 0 3 3 3 1 ERp29, N-terminal domain DSBA PF01323.20 KPA40658.1 - 0.018 14.9 0.1 6.4 6.5 0.0 3.1 3 0 0 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KPA40658.1 - 0.036 14.2 4.3 1.7 8.8 0.2 3.8 3 2 0 3 3 3 0 Thioredoxin Thioredoxin_3 PF13192.6 KPA40658.1 - 0.076 13.1 0.1 0.45 10.6 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin domain Oxidored_FMN PF00724.20 KPA40659.1 - 5.8e-67 226.4 0.0 7.8e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans_2 PF11951.8 KPA40660.1 - 1.7e-25 89.6 4.2 1.6e-19 70.0 2.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain GATase_6 PF13522.6 KPA40661.1 - 7.7e-15 55.3 0.0 1.6e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KPA40661.1 - 3.8e-11 43.0 0.0 8e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KPA40661.1 - 1e-06 28.4 0.1 2.3e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Transp_cyt_pur PF02133.15 KPA40662.1 - 4.6e-152 506.8 32.9 5.3e-152 506.6 32.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin IBN_N PF03810.19 KPA40663.1 - 3.9e-10 39.5 0.3 3e-09 36.7 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KPA40663.1 - 0.00076 19.6 0.0 0.016 15.3 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein CAS_CSE1 PF03378.15 KPA40663.1 - 0.0074 14.8 0.0 0.013 14.0 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Ribosomal_60s PF00428.19 KPA40663.1 - 0.034 14.7 1.3 0.094 13.3 1.3 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein His_kinase PF06580.13 KPA40663.1 - 0.24 11.7 0.8 2.1 8.7 0.0 3.1 4 0 0 4 4 4 0 Histidine kinase PI31_Prot_N PF11566.8 KPA40664.1 - 7.4e-59 198.2 0.0 9.2e-59 197.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KPA40664.1 - 8e-19 68.6 17.9 8e-19 68.6 17.9 2.5 3 1 0 3 3 3 1 PI31 proteasome regulator Baculo_LEF-2 PF03041.14 KPA40664.1 - 0.054 13.1 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 lef-2 LisH PF08513.11 KPA40664.1 - 0.16 12.0 0.9 4.1 7.5 0.1 2.3 2 0 0 2 2 2 0 LisH HORMA PF02301.18 KPA40665.1 - 1.7e-12 47.4 0.0 1.9e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 HORMA domain RhoGEF PF00621.20 KPA40666.1 - 6.4e-26 91.7 0.2 1.6e-25 90.4 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 KPA40666.1 - 0.0008 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Seadorna_Vp10 PF07322.11 KPA40666.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus Vp10 DUF148 PF02520.17 KPA40666.1 - 0.3 11.2 3.0 0.38 10.9 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 ING PF12998.7 KPA40666.1 - 1.5 9.5 4.4 6.6 7.4 0.5 3.6 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Amino_oxidase PF01593.24 KPA40667.1 - 8.8e-56 190.1 1.6 3.5e-53 181.5 1.6 2.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA40667.1 - 1.2e-08 35.0 0.0 2.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPA40667.1 - 0.0053 15.9 0.0 0.0094 15.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA40667.1 - 0.043 13.4 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA40667.1 - 0.062 12.0 0.1 1.9 7.1 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Dcc1 PF09724.9 KPA40668.1 - 4.1e-13 49.3 0.0 4.9e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Rad4 PF03835.15 KPA40670.1 - 1.2e-27 96.4 12.5 4.9e-26 91.2 12.5 3.1 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KPA40670.1 - 3.1e-27 94.8 1.3 6.6e-27 93.7 0.6 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KPA40670.1 - 9.9e-20 70.1 0.5 2.6e-19 68.8 0.5 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KPA40670.1 - 7.5e-16 58.8 1.8 7.5e-16 58.8 1.8 6.1 7 2 0 7 7 7 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KPA40670.1 - 0.019 15.4 0.6 0.096 13.1 0.2 2.5 2 1 0 2 2 2 0 Transglutaminase-like superfamily zf-AN1 PF01428.16 KPA40671.1 - 1.1e-24 86.3 22.8 1.2e-12 47.8 6.9 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 KPA40671.1 - 0.013 15.7 5.0 0.013 15.7 5.0 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 KPA40671.1 - 0.029 14.7 15.3 0.79 10.1 5.2 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain MTP18 PF10558.9 KPA40672.1 - 5.2e-82 273.9 0.1 7.2e-82 273.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) ATP19 PF11022.8 KPA40673.1 - 3e-26 91.6 0.0 3.5e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K HTH_Tnp_Tc5 PF03221.16 KPA40675.1 - 1.7e-14 53.6 0.1 3.7e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Cep57_CLD_2 PF14197.6 KPA40675.1 - 0.032 14.3 2.9 0.064 13.3 2.9 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 EAP30 PF04157.16 KPA40676.1 - 6.9e-43 146.6 0.1 9.5e-43 146.2 0.1 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 KPA40676.1 - 1.4e-23 82.1 1.5 1.4e-23 82.1 1.5 2.9 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 KPA40676.1 - 2.7e-22 78.7 0.0 4.8e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 KPA40676.1 - 0.00017 20.9 1.0 0.00017 20.9 1.0 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KPA40676.1 - 0.00059 19.8 6.2 0.024 14.7 0.3 2.5 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger GRAM PF02893.20 KPA40676.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 GRAM domain DZR PF12773.7 KPA40676.1 - 1.8 8.6 7.7 0.11 12.6 0.9 2.2 2 1 0 2 2 2 0 Double zinc ribbon SAC3_GANP PF03399.16 KPA40677.1 - 1.1e-23 84.1 2.5 1.2e-21 77.3 2.5 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KPA40677.1 - 0.024 14.6 0.1 0.071 13.1 0.0 1.8 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family SH3_1 PF00018.28 KPA40678.1 - 1.5e-27 94.9 0.0 8.5e-14 50.9 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KPA40678.1 - 1.7e-18 66.2 0.1 2.3e-09 37.0 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KPA40678.1 - 2.5e-14 53.2 0.0 5.2e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 KPA40678.1 - 3.7e-11 42.5 0.0 6e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 KPA40678.1 - 2.8e-07 30.4 0.1 5.2e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 PB1 domain Rad60-SLD PF11976.8 KPA40678.1 - 0.024 14.5 0.0 0.083 12.7 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Pex14_N PF04695.13 KPA40678.1 - 1.2 9.8 14.3 1.2 9.8 2.9 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ion_trans PF00520.31 KPA40680.1 - 1.6e-11 43.9 23.8 3.8e-11 42.7 23.8 1.6 1 1 0 1 1 1 1 Ion transport protein PNTB_4TM PF12769.7 KPA40680.1 - 0.018 15.5 0.1 0.078 13.4 0.1 2.1 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch RTA1 PF04479.13 KPA40681.1 - 3.2e-46 157.6 12.7 3.8e-46 157.3 12.7 1.1 1 0 0 1 1 1 1 RTA1 like protein GWT1 PF06423.12 KPA40681.1 - 3.8 7.6 7.1 1.1 9.3 1.3 2.3 1 1 0 2 2 2 0 GWT1 Plasmodium_Vir PF05795.11 KPA40682.1 - 0.0079 15.7 4.0 0.01 15.3 4.0 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein EphA2_TM PF14575.6 KPA40682.1 - 0.16 12.9 0.0 0.39 11.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 KPA40682.1 - 0.17 10.6 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Apt1 PF10351.9 KPA40682.1 - 0.63 8.8 5.8 0.77 8.5 5.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KPA40682.1 - 0.71 8.6 3.5 0.98 8.1 3.5 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 KPA40682.1 - 2.2 6.7 5.5 2.8 6.4 5.5 1.1 1 0 0 1 1 1 0 Macoilin family DUF5305 PF17231.2 KPA40682.1 - 5.2 6.4 7.5 67 2.8 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 KPA40682.1 - 6.2 6.7 13.7 2.8e+02 1.4 13.7 2.2 1 1 0 1 1 1 0 TMEM154 protein family Mitofilin PF09731.9 KPA40684.1 - 3.5e-143 478.7 22.5 1.2e-124 417.5 22.6 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein CAS_C PF12026.8 KPA40684.1 - 0.013 15.6 1.6 0.033 14.3 1.6 1.7 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain DUF2935 PF11155.8 KPA40684.1 - 0.021 15.2 3.0 0.057 13.7 3.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Ras PF00071.22 KPA40685.1 - 1.5e-58 196.9 0.4 1.8e-58 196.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA40685.1 - 3e-36 124.3 0.2 6.9e-36 123.1 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA40685.1 - 9.9e-15 54.4 0.1 1.2e-14 54.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KPA40685.1 - 1.9e-07 30.7 0.0 2.4e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KPA40685.1 - 3.1e-07 30.1 0.0 4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KPA40685.1 - 3.3e-06 27.2 0.0 6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA40685.1 - 8.6e-06 25.8 1.3 0.032 14.1 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KPA40685.1 - 0.027 14.9 0.3 0.055 13.9 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain GbpA_2 PF18416.1 KPA40685.1 - 0.065 13.5 1.1 5.1 7.4 1.1 2.3 1 1 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 TniB PF05621.11 KPA40685.1 - 0.091 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 KPA40685.1 - 0.13 11.4 0.3 2.6 7.1 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 KPA40685.1 - 0.14 12.5 0.1 4.6 7.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain Syja_N PF02383.18 KPA40686.1 - 4.3e-88 295.7 0.0 6.5e-88 295.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain tRNA-synt_1 PF00133.22 KPA40688.1 - 1.9e-152 508.6 0.0 2.6e-152 508.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KPA40688.1 - 3.9e-19 68.7 0.0 1.6e-12 46.9 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KPA40688.1 - 4.1e-17 62.5 0.0 7.6e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KPA40688.1 - 0.011 15.1 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 KPA40688.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 KPA40688.1 - 0.1 12.5 4.3 0.27 11.1 4.3 1.8 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS CCDC144C PF14915.6 KPA40689.1 - 0.08 12.0 0.7 0.11 11.6 0.7 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Tom37 PF10568.9 KPA40690.1 - 8.3e-39 132.7 0.3 1.3e-38 132.1 0.3 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KPA40690.1 - 8e-10 39.3 0.0 3.8e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KPA40690.1 - 8.8e-09 35.0 0.0 1.9e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPA40690.1 - 0.038 14.0 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PIG-U PF06728.13 KPA40691.1 - 7.3e-122 407.1 26.1 8.4e-122 406.9 26.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 KPA40691.1 - 2e-05 24.6 0.6 2e-05 24.6 0.6 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) 8TM_micro PF17028.5 KPA40691.1 - 1.2 8.8 7.8 4.2 7.0 7.3 1.9 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Pescadillo_N PF06732.11 KPA40692.1 - 2.6e-122 407.7 0.0 6.1e-122 406.4 0.0 1.6 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 KPA40692.1 - 0.055 13.9 0.0 0.25 11.8 0.0 2.2 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Astro_capsid_p PF12226.8 KPA40692.1 - 4 6.5 17.5 0.39 9.8 11.9 2.0 1 1 1 2 2 2 0 Turkey astrovirus capsid protein Nop53 PF07767.11 KPA40692.1 - 5.9 6.2 32.3 0.042 13.3 22.9 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) RRN9 PF10680.9 KPA40693.1 - 1.1e-14 54.4 1.7 7.2e-14 51.8 1.7 2.5 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor AT_hook PF02178.19 KPA40693.1 - 0.043 13.7 12.6 1 9.5 2.4 3.1 2 0 0 2 2 2 0 AT hook motif zf-H2C2_5 PF13909.6 KPA40693.1 - 0.076 12.8 0.9 0.18 11.6 0.9 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Kinesin PF00225.23 KPA40694.1 - 6.7e-110 367.1 1.4 1.9e-109 365.6 1.4 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPA40694.1 - 5.1e-26 91.4 0.2 5.1e-26 91.4 0.2 3.1 3 1 1 4 4 4 1 Microtubule binding Microtub_bind PF13931.6 KPA40694.1 - 2.4e-06 28.0 0.1 2.4e-06 28.0 0.1 5.3 5 1 0 5 5 5 1 Kinesin-associated microtubule-binding Apolipoprotein PF01442.18 KPA40694.1 - 0.00025 21.0 14.7 0.00025 21.0 14.7 4.5 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KPA40694.1 - 0.14 12.1 32.0 0.068 13.2 0.8 6.7 2 1 6 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.8 KPA40694.1 - 0.15 12.4 0.1 0.15 12.4 0.1 6.4 1 1 6 7 7 7 0 YlqD protein Zip PF02535.22 KPA40694.1 - 3.9 6.6 4.6 1.5 7.9 1.5 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter PPP4R2 PF09184.11 KPA40695.1 - 0.00023 20.8 29.5 0.6 9.6 29.5 3.0 1 1 0 1 1 1 1 PPP4R2 SPRY PF00622.28 KPA40696.1 - 1.2e-05 25.3 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Na_Ca_ex PF01699.24 KPA40697.1 - 1.2e-39 135.6 39.1 3e-22 79.2 17.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TT_ORF1 PF02956.14 KPA40697.1 - 3.2 6.3 5.2 6 5.4 5.2 1.3 1 0 0 1 1 1 0 TT viral orf 1 DUF3087 PF11286.8 KPA40697.1 - 3.3 7.2 5.7 0.39 10.2 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) DUF872 PF05915.12 KPA40697.1 - 3.4 7.8 5.3 59 3.9 1.0 3.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) SpoIIIAH PF12685.7 KPA40697.1 - 4.1 7.2 10.3 1.4 8.7 2.6 2.5 2 1 0 2 2 2 0 SpoIIIAH-like protein Pkinase PF00069.25 KPA40698.1 - 1.1e-63 215.0 0.0 2e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40698.1 - 1.6e-36 125.9 0.0 1.1e-30 106.8 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KPA40698.1 - 6e-07 29.1 0.1 0.00014 21.2 0.1 2.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KPA40698.1 - 9.2e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KPA40698.1 - 0.016 14.2 0.2 0.025 13.6 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KPA40698.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KPA40698.1 - 0.091 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family GWT1 PF06423.12 KPA40699.1 - 2.5e-43 147.8 1.8 2.5e-43 147.8 1.8 2.5 2 1 1 3 3 3 1 GWT1 DUF4818 PF16089.5 KPA40699.1 - 0.0089 16.5 0.1 0.0089 16.5 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4818) Tub_N PF16322.5 KPA40701.1 - 0.057 13.8 0.4 0.082 13.3 0.4 1.2 1 0 0 1 1 1 0 Tubby N-terminal tRNA-synt_2 PF00152.20 KPA40702.1 - 1.8e-70 237.6 0.0 2.8e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KPA40702.1 - 4.7e-13 48.8 0.5 6.5e-13 48.4 0.5 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KPA40702.1 - 1.5e-05 24.9 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Abhydrolase_3 PF07859.13 KPA40703.1 - 1.8e-41 142.3 0.0 2.5e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPA40703.1 - 3.2e-08 32.9 0.0 6.3e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KPA40703.1 - 0.00011 21.7 0.0 0.5 9.8 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KPA40703.1 - 0.00065 20.4 1.1 0.0011 19.6 0.6 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KPA40703.1 - 0.01 15.7 0.0 0.098 12.5 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase GLTP PF08718.11 KPA40704.1 - 1.8e-46 158.1 0.0 3.9e-46 157.0 0.0 1.5 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Apolipoprotein PF01442.18 KPA40704.1 - 0.068 13.0 0.2 1.3 8.9 0.0 2.2 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain PLDc_2 PF13091.6 KPA40706.1 - 1.4e-17 63.9 0.1 6e-06 26.2 0.0 3.9 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KPA40706.1 - 1.2e-15 56.9 1.1 2.6e-08 33.7 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif p450 PF00067.22 KPA40707.1 - 2.4e-85 287.0 0.0 3.5e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KPA40707.1 - 1.3e-28 100.1 0.0 2.1e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KPA40707.1 - 1.3e-25 90.2 0.1 9.5e-25 87.5 0.0 2.4 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KPA40707.1 - 2.6e-11 44.1 0.0 7.4e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KPA40707.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain PT-TG PF14449.6 KPA40707.1 - 0.062 13.2 0.1 2 8.4 0.1 2.6 2 0 0 2 2 2 0 Pre-toxin TG zf-RING_2 PF13639.6 KPA40708.1 - 5.9e-15 55.3 17.1 4.8e-14 52.4 7.9 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 KPA40708.1 - 3.2e-12 46.1 9.1 3.2e-09 36.5 3.3 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPA40708.1 - 1e-11 44.3 7.2 1.6e-11 43.7 4.0 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KPA40708.1 - 1.1e-10 41.1 15.5 4.5e-10 39.2 7.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA40708.1 - 2.4e-08 33.7 14.3 1.4e-06 28.1 7.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KPA40708.1 - 8.2e-08 32.4 6.0 8.2e-08 32.4 6.0 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KPA40708.1 - 4.9e-07 29.6 11.6 3e-06 27.1 4.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPA40708.1 - 8e-07 29.0 7.5 6.2e-06 26.1 1.1 2.7 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KPA40708.1 - 5.8e-06 26.1 11.1 5.8e-05 22.9 4.7 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KPA40708.1 - 0.0094 16.0 2.0 0.0094 16.0 2.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 KPA40708.1 - 0.016 15.2 0.3 0.016 15.2 0.3 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KPA40708.1 - 0.018 15.3 3.0 0.018 15.3 3.0 2.5 2 0 0 2 2 2 0 zinc-ribbon zf-P11 PF03854.14 KPA40708.1 - 0.019 14.7 2.0 0.019 14.7 2.0 2.3 2 0 0 2 2 2 0 P-11 zinc finger Prok-RING_1 PF14446.6 KPA40708.1 - 0.026 14.5 11.1 1.4 8.9 0.9 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 PhnA_Zn_Ribbon PF08274.12 KPA40708.1 - 0.031 14.2 1.6 1.9 8.5 0.1 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-C3HC4_4 PF15227.6 KPA40708.1 - 0.096 12.9 10.8 0.4 10.9 0.5 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 KPA40708.1 - 0.1 12.6 7.5 1.9 8.5 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbons DNA_ligase_ZBD PF03119.16 KPA40708.1 - 0.12 12.4 2.2 2.4 8.3 0.1 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn_ribbon_17 PF17120.5 KPA40708.1 - 0.17 11.5 14.3 0.22 11.2 5.1 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KPA40708.1 - 0.23 11.4 13.1 0.25 11.3 5.5 2.5 2 0 0 2 2 2 0 PHD-finger RINGv PF12906.7 KPA40708.1 - 0.29 11.3 16.6 0.076 13.1 8.8 2.4 2 0 0 2 2 2 0 RING-variant domain zf-RING_4 PF14570.6 KPA40708.1 - 0.35 10.7 13.0 0.13 12.1 4.5 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 KPA40708.1 - 0.38 10.9 10.8 0.11 12.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) TackOD1 PF18551.1 KPA40708.1 - 0.63 9.7 3.7 2.3 7.8 0.2 2.3 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 KPA40708.1 - 4.7 7.3 6.9 26 5.0 1.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon MFS_1 PF07690.16 KPA40709.1 - 0.092 11.7 0.3 0.11 11.5 0.3 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily SHR3_chaperone PF08229.11 KPA40709.1 - 5.7 5.9 5.5 0.68 8.9 1.1 1.7 2 1 0 2 2 2 0 ER membrane protein SH3 Ribonucleas_3_3 PF14622.6 KPA40710.1 - 3.4e-08 33.7 0.0 0.01 16.0 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 KPA40710.1 - 1.5e-05 25.6 0.0 4e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KPA40710.1 - 0.0016 19.1 0.0 0.0061 17.2 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain PLA2_B PF01735.18 KPA40711.1 - 2.8e-28 98.6 0.0 5.2e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Lysophospholipase catalytic domain THOC7 PF05615.13 KPA40711.1 - 0.0047 17.2 1.2 0.0047 17.2 1.2 2.4 2 0 0 2 2 2 1 Tho complex subunit 7 PTS_IIA PF02255.16 KPA40711.1 - 0.15 12.1 4.8 0.41 10.7 4.8 1.7 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF2229 PF09989.9 KPA40711.1 - 0.23 11.1 1.0 0.43 10.2 0.1 1.8 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Atrophin-1 PF03154.15 KPA40711.1 - 2 6.6 5.2 3.3 5.9 5.2 1.3 1 0 0 1 1 1 0 Atrophin-1 family DivIVA PF05103.13 KPA40711.1 - 3.3 7.8 13.5 0.62 10.2 6.8 2.4 2 0 0 2 2 2 0 DivIVA protein La PF05383.17 KPA40712.1 - 1.3e-17 63.6 0.0 2.3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KPA40712.1 - 2.4e-09 36.9 0.2 4.3e-09 36.0 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPA40712.1 - 0.097 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Tmp39 PF10271.9 KPA40712.1 - 0.34 9.9 0.0 0.51 9.3 0.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein Inositol_P PF00459.25 KPA40713.1 - 8.7e-64 215.6 0.0 1e-63 215.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family His_Phos_2 PF00328.22 KPA40715.1 - 1.9e-64 218.4 0.0 2.2e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF465 PF04325.13 KPA40715.1 - 0.063 13.3 0.4 0.3 11.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Npa1 PF11707.8 KPA40717.1 - 3e-99 332.6 0.1 8.1e-99 331.2 0.1 1.8 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KPA40717.1 - 6.2e-65 218.6 2.7 7.9e-64 215.0 0.3 3.3 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Chitin_synth_2 PF03142.15 KPA40718.1 - 4.3e-245 814.3 1.5 6e-245 813.8 1.5 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KPA40718.1 - 2.4e-74 250.8 0.0 1.1e-73 248.6 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KPA40718.1 - 2.4e-16 59.4 0.1 8.8e-16 57.6 0.2 1.9 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KPA40718.1 - 4.2e-16 58.8 0.3 2.2e-11 43.7 0.0 3.9 4 0 0 4 4 4 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KPA40718.1 - 6.7e-13 49.0 3.5 1.8e-12 47.6 3.5 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KPA40718.1 - 1.7e-11 44.5 0.0 9.7e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPA40718.1 - 3e-06 27.1 0.0 0.0054 16.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 RsgA_GTPase PF03193.16 KPA40718.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 KPA40718.1 - 0.033 14.7 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KPA40718.1 - 0.075 13.3 0.3 0.45 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KPA40718.1 - 0.1 13.0 0.3 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KPA40718.1 - 0.13 12.1 0.0 0.49 10.2 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain Chitin_synth_2 PF03142.15 KPA40719.1 - 2.5e-229 762.3 0.1 4.2e-229 761.6 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KPA40719.1 - 1.9e-15 57.3 1.2 4.9e-15 56.0 1.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DEK_C PF08766.11 KPA40719.1 - 1e-14 54.2 0.5 5.3e-14 51.9 0.8 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 KPA40719.1 - 3.6e-12 46.7 0.0 1.8e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 KPA40719.1 - 3.4e-09 36.7 0.2 6.9e-06 26.1 0.0 2.9 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Myosin_head PF00063.21 KPA40719.1 - 5.3e-07 28.3 0.0 1.2e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Glycos_transf_2 PF00535.26 KPA40719.1 - 0.00019 21.3 0.0 0.045 13.6 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KPA40719.1 - 0.00022 20.8 0.0 0.00063 19.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Wzy_C PF04932.15 KPA40719.1 - 0.0075 15.9 0.2 2.2 7.9 0.0 3.0 3 0 0 3 3 3 1 O-Antigen ligase JCAD PF15351.6 KPA40719.1 - 0.11 10.2 0.4 0.16 9.7 0.4 1.1 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease BCDHK_Adom3 PF10436.9 KPA40720.1 - 1.9e-48 164.3 0.0 2.6e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KPA40720.1 - 1.6e-10 41.5 0.0 5.6e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KPA40720.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF5615 PF18480.1 KPA40720.1 - 0.13 12.1 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) Arginosuc_synth PF00764.19 KPA40721.1 - 1.4e-45 156.2 0.0 1.6e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KPA40721.1 - 0.00038 20.0 0.0 0.0005 19.6 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 KPA40721.1 - 0.0061 16.3 0.0 0.0066 16.1 0.0 1.0 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.16 KPA40721.1 - 0.022 13.6 0.0 0.032 13.0 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase Arginosuc_synth PF00764.19 KPA40722.1 - 4.8e-81 273.0 0.0 5.3e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase p450 PF00067.22 KPA40724.1 - 1e-43 149.8 0.0 1.4e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 KPA40725.1 - 1.3e-32 113.2 0.0 2e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KPA40726.1 - 5.8e-12 45.2 0.1 6.9e-11 41.7 0.1 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Flavin_Reduct PF01613.18 KPA40727.1 - 3.9e-18 66.0 0.0 6.2e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain GFO_IDH_MocA PF01408.22 KPA40728.1 - 4.6e-19 69.4 0.0 7.2e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KPA40728.1 - 0.06 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain LEA_3 PF03242.13 KPA40730.1 - 0.042 14.6 0.0 0.16 12.7 0.0 2.0 1 0 0 1 1 1 0 Late embryogenesis abundant protein Zn_clus PF00172.18 KPA40731.1 - 7.5e-08 32.4 13.9 1.1e-07 31.8 13.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA40732.1 - 1.7e-20 73.1 0.2 3.2e-20 72.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gag_spuma PF03276.14 KPA40732.1 - 0.37 9.2 7.3 0.57 8.6 7.3 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Zeta_toxin PF06414.12 KPA40733.1 - 0.00032 20.0 0.0 0.00067 19.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KPA40733.1 - 0.0018 18.5 0.1 0.0038 17.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KPA40733.1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Torsin PF06309.11 KPA40733.1 - 0.019 15.1 0.0 0.073 13.2 0.0 2.0 2 0 0 2 2 2 0 Torsin AAA_18 PF13238.6 KPA40733.1 - 0.038 14.5 0.0 0.12 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KPA40733.1 - 0.084 13.4 0.3 0.16 12.5 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KPA40733.1 - 0.086 13.2 0.3 0.14 12.5 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KPA40733.1 - 0.12 12.2 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KPA40733.1 - 0.13 12.8 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 KPA40733.1 - 0.17 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KPA40733.1 - 0.19 12.1 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Iso_dh PF00180.20 KPA40734.1 - 1.5e-85 287.4 0.0 1.9e-85 287.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4875 PF16175.5 KPA40734.1 - 0.022 14.9 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) IBR PF01485.21 KPA40735.1 - 7.6e-11 42.1 35.0 3.2e-07 30.5 13.3 3.5 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain Sugar_tr PF00083.24 KPA40736.1 - 1.9e-127 425.9 17.4 2.2e-127 425.7 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA40736.1 - 4.3e-21 75.2 31.9 4.3e-15 55.5 9.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.21 KPA40736.1 - 4.4 6.6 11.3 0.26 10.6 1.3 2.5 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) FAD_binding_2 PF00890.24 KPA40737.1 - 8.6e-86 288.6 1.0 1.2e-85 288.1 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.28 KPA40737.1 - 1.8e-21 76.0 0.0 2.1e-20 72.6 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KPA40737.1 - 9.4e-15 55.0 0.6 3e-14 53.4 0.6 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KPA40737.1 - 1.9e-09 37.4 0.7 8e-09 35.3 0.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA40737.1 - 6.4e-08 32.7 0.6 5.6e-07 29.7 0.4 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA40737.1 - 9e-07 28.4 0.4 9.4e-06 25.1 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA40737.1 - 2.1e-06 27.2 0.1 0.015 14.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA40737.1 - 1.2e-05 24.2 2.9 0.01 14.5 0.3 3.3 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 KPA40737.1 - 0.00033 19.8 4.0 0.2 10.7 1.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KPA40737.1 - 0.00047 19.6 0.9 0.27 10.5 0.2 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 KPA40737.1 - 0.00057 19.2 2.0 0.058 12.6 0.7 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KPA40737.1 - 0.0023 17.2 2.2 0.0056 16.0 2.2 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KPA40737.1 - 0.014 15.9 3.2 2.1 9.0 0.5 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KPA40737.1 - 0.042 13.1 0.8 0.081 12.2 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fasciclin PF02469.22 KPA40738.1 - 0.00097 19.4 0.0 0.0017 18.6 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain SRF-TF PF00319.18 KPA40739.1 - 1.5e-22 78.8 0.3 2.6e-22 78.0 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3591 PF12157.8 KPA40740.1 - 4.4e-176 585.9 1.8 4.4e-176 585.9 1.8 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KPA40740.1 - 0.0048 16.9 0.7 0.0098 15.9 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KPA40740.1 - 0.27 11.1 1.7 0.62 10.0 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle AA_permease PF00324.21 KPA40741.1 - 1.5e-92 310.7 35.8 1.8e-92 310.4 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA40741.1 - 2.1e-23 82.9 38.3 2.6e-23 82.5 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease Amidase PF01425.21 KPA40742.1 - 5.8e-109 365.0 0.0 7.9e-109 364.6 0.0 1.2 1 0 0 1 1 1 1 Amidase BPL_N PF09825.9 KPA40742.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal FAD_binding_3 PF01494.19 KPA40743.1 - 1.6e-24 86.8 0.0 2.5e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA40743.1 - 8.9e-07 28.4 0.1 0.0002 20.7 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA40743.1 - 8.5e-06 26.2 0.0 0.00049 20.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA40743.1 - 3e-05 23.8 0.5 0.00094 18.9 0.2 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPA40743.1 - 0.0039 16.3 0.5 0.0062 15.7 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KPA40743.1 - 0.014 14.7 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA40743.1 - 0.031 14.5 0.1 0.072 13.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ANXA2R PF15721.5 KPA40743.1 - 0.055 14.0 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Annexin-2 receptor ApbA PF02558.16 KPA40743.1 - 0.18 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ABM PF03992.16 KPA40744.1 - 2.7e-06 27.4 0.1 3.8e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase FemAB_like PF04339.12 KPA40744.1 - 0.00044 19.5 0.1 0.0005 19.3 0.1 1.0 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition MFS_1 PF07690.16 KPA40745.1 - 7.5e-33 113.9 33.4 3.1e-32 111.9 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3522 PF12036.8 KPA40745.1 - 0.031 14.6 0.1 0.031 14.6 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) SBP56 PF05694.11 KPA40746.1 - 3.8e-07 29.3 0.0 0.0012 17.8 0.0 2.6 2 1 0 2 2 2 2 56kDa selenium binding protein (SBP56) Nup160 PF11715.8 KPA40746.1 - 0.23 10.0 0.0 0.33 9.5 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Cupin_1 PF00190.22 KPA40747.1 - 3.3e-33 114.4 0.0 8.6e-19 67.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KPA40747.1 - 2.1e-21 75.4 1.8 2.9e-11 42.9 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KPA40747.1 - 0.00012 21.7 0.0 0.092 12.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KPA40747.1 - 0.0086 16.0 1.2 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_4 PF08007.12 KPA40747.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein 3-HAO PF06052.12 KPA40747.1 - 0.037 13.7 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase GRIM-19 PF06212.12 KPA40749.1 - 8e-24 84.1 0.1 2.3e-23 82.6 0.1 1.6 1 1 0 1 1 1 1 GRIM-19 protein adh_short PF00106.25 KPA40750.1 - 6.7e-18 64.8 0.0 3.4e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KPA40750.1 - 3.2e-07 30.4 0.0 1.5e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 KPA40750.1 - 6.7e-07 29.1 0.0 2e-05 24.3 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPA40750.1 - 2.6e-06 27.1 0.0 3.4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPA40750.1 - 0.049 12.7 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NIF PF03031.18 KPA40751.1 - 6.8e-28 97.4 0.2 2.2e-27 95.8 0.0 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KPA40751.1 - 4.5e-08 33.4 0.0 2.1e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KPA40751.1 - 5.2e-05 23.1 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KPA40751.1 - 0.00088 19.6 0.0 0.0024 18.3 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Biotin_lipoyl PF00364.22 KPA40751.1 - 0.0019 18.0 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme RTT107_BRCT_5 PF16770.5 KPA40751.1 - 0.0043 16.9 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KPA40751.1 - 0.011 15.8 0.1 0.028 14.5 0.1 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KPA40751.1 - 0.014 15.6 0.1 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Biotin_lipoyl_2 PF13533.6 KPA40751.1 - 0.088 12.6 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like Ribosomal_S2 PF00318.20 KPA40751.1 - 0.28 10.4 1.0 0.46 9.7 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S2 Cnd1_N PF12922.7 KPA40752.1 - 1.3e-64 217.0 0.4 1.1e-63 214.0 0.2 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KPA40752.1 - 1.9e-48 164.6 5.9 3.7e-44 150.6 0.0 4.5 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KPA40752.1 - 1.5e-10 40.4 6.0 0.036 14.3 0.0 6.7 6 0 0 6 6 5 2 HEAT repeat HEAT_2 PF13646.6 KPA40752.1 - 6.5e-10 39.3 3.0 0.00013 22.2 0.1 5.0 4 1 1 5 5 4 2 HEAT repeats HEAT_EZ PF13513.6 KPA40752.1 - 9.4e-06 26.0 5.0 0.044 14.3 0.2 5.0 4 0 0 4 4 4 1 HEAT-like repeat Cnd3 PF12719.7 KPA40752.1 - 0.00058 19.2 6.4 0.0011 18.2 0.4 3.9 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 KPA40752.1 - 0.0041 17.3 0.1 4.2 7.6 0.0 3.6 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Ald_Xan_dh_C2 PF02738.18 KPA40752.1 - 0.013 14.0 0.0 0.02 13.4 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase MIEAP PF16026.5 KPA40752.1 - 0.044 14.0 0.1 0.16 12.1 0.1 2.0 1 0 0 1 1 1 0 Mitochondria-eating protein DUF2408 PF10303.9 KPA40752.1 - 0.79 10.3 4.3 4.6 7.8 0.3 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2408) DUF5526 PF17664.1 KPA40752.1 - 2.1 7.9 7.4 0.2 11.2 2.6 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5526) Pkinase PF00069.25 KPA40753.1 - 4.9e-43 147.4 0.0 9.2e-40 136.7 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40753.1 - 1.4e-14 54.0 0.0 6.8e-10 38.7 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPA40753.1 - 3e-05 23.0 0.3 0.0012 17.7 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KPA40753.1 - 0.037 13.9 6.9 0.038 13.9 0.0 3.1 3 1 1 4 4 4 0 Phosphotransferase enzyme family XRN_M PF17846.1 KPA40753.1 - 0.35 9.8 5.1 0.5 9.2 5.1 1.2 1 0 0 1 1 1 0 Xrn1 helical domain CCDC53 PF10152.9 KPA40753.1 - 3.7 7.9 8.6 5.3 7.4 7.5 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ribosomal_L27A PF00828.19 KPA40754.1 - 6.1e-21 75.4 0.0 1.1e-20 74.6 0.0 1.4 1 1 1 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Helicase_C_2 PF13307.6 KPA40755.1 - 6e-59 199.1 0.0 1.2e-58 198.0 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KPA40755.1 - 2.7e-42 144.4 0.0 5.1e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KPA40755.1 - 0.0011 19.0 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KPA40755.1 - 0.029 14.6 0.1 14 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KPA40755.1 - 0.04 13.7 0.3 1.1 9.0 0.3 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.16 KPA40755.1 - 0.091 12.2 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Transp_cyt_pur PF02133.15 KPA40756.1 - 1e-34 120.1 35.5 1.6e-33 116.1 35.5 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2517 PF10725.9 KPA40756.1 - 1.2 9.0 0.0 1.2 9.0 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2517) p450 PF00067.22 KPA40757.1 - 4.1e-32 111.5 0.0 6.8e-32 110.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Na_H_Exchanger PF00999.21 KPA40758.1 - 3.8e-50 170.8 15.7 5e-50 170.4 15.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3112 PF11309.8 KPA40758.1 - 0.07 12.6 0.1 0.19 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) 60KD_IMP PF02096.20 KPA40758.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein Sporozoite_P67 PF05642.11 KPA40759.1 - 0.013 13.7 7.6 0.016 13.3 7.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 KPA40759.1 - 4.4 7.8 12.5 0.23 11.9 4.2 2.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Acetyltransf_1 PF00583.25 KPA40760.1 - 4.5e-09 36.6 0.0 5.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA40760.1 - 1.5e-08 34.6 0.0 2.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA40760.1 - 1.2e-05 25.6 0.0 1.8e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA40760.1 - 0.055 13.4 0.0 0.18 11.8 0.0 1.9 1 1 1 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.7 KPA40760.1 - 0.15 12.1 0.1 1.3 9.1 0.1 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Torus PF16131.5 KPA40761.1 - 1e-05 26.2 0.1 2.7e-05 24.8 0.1 1.7 2 0 0 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 KPA40761.1 - 1.2e-05 25.0 3.7 2.3e-05 24.1 3.7 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KPA40761.1 - 5.8e-05 23.0 5.3 0.00011 22.1 5.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KPA40761.1 - 0.00035 20.4 0.9 0.00069 19.5 0.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KPA40761.1 - 0.41 11.2 6.4 0.77 10.3 6.4 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PP-binding PF00550.25 KPA40762.1 - 1.6e-11 44.4 0.2 2.3e-11 43.9 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KPA40762.1 - 0.00015 22.0 0.4 0.00027 21.1 0.4 1.4 1 1 0 1 1 1 1 Acyl-carrier Peptidase_M14 PF00246.24 KPA40763.1 - 1.4e-37 130.1 0.2 1.9e-37 129.7 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Fer4 PF00037.27 KPA40764.1 - 3.7e-13 48.7 16.5 9.2e-08 31.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KPA40764.1 - 1.3e-12 48.1 10.3 2.1e-12 47.4 10.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KPA40764.1 - 3.7e-09 37.4 10.2 0.00018 22.3 0.8 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KPA40764.1 - 1.4e-08 34.7 31.6 1.1e-05 25.5 12.3 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 KPA40764.1 - 3.1e-08 33.6 9.1 5.6e-08 32.8 9.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KPA40764.1 - 3.5e-08 33.4 21.2 3.3e-06 27.1 12.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KPA40764.1 - 3e-06 27.6 19.2 0.00038 20.8 11.2 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KPA40764.1 - 3.4e-06 26.9 17.1 0.00059 19.8 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KPA40764.1 - 7.9e-06 25.7 11.4 0.013 15.6 1.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KPA40764.1 - 3.6e-05 23.9 12.3 0.00075 19.8 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KPA40764.1 - 0.00059 20.3 11.4 0.054 14.0 12.5 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KPA40764.1 - 0.032 14.5 5.9 0.8 10.0 0.3 2.4 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 KPA40764.1 - 0.038 14.5 12.9 1.1 9.9 4.3 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 KPA40764.1 - 0.12 12.5 5.6 0.31 11.2 0.4 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_18 PF13746.6 KPA40764.1 - 0.22 11.7 9.2 1.8 8.8 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KPA40764.1 - 0.49 11.5 15.5 0.62 11.1 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KPA40764.1 - 1.2 10.0 11.6 5.2 8.0 2.0 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain adh_short PF00106.25 KPA40766.1 - 5.3e-31 107.6 0.0 9.4e-24 83.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA40766.1 - 8.1e-17 61.6 0.0 4.1e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA40766.1 - 2.5e-09 37.3 0.0 3.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KPA40767.1 - 5.5e-19 68.7 0.0 6.9e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA40767.1 - 8.9e-12 45.3 0.0 1.7e-11 44.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KPA40767.1 - 0.0064 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KPA40767.1 - 0.0096 16.0 0.1 0.027 14.6 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DUF2853 PF11015.8 KPA40767.1 - 0.015 16.0 0.1 0.18 12.5 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2853) Semialdhyde_dh PF01118.24 KPA40767.1 - 0.016 15.6 0.3 0.085 13.3 0.1 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KPA40767.1 - 0.025 13.8 0.2 0.39 9.8 0.0 2.5 2 1 1 3 3 3 0 Male sterility protein Epimerase PF01370.21 KPA40767.1 - 0.031 13.7 0.1 0.19 11.2 0.0 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KPA40767.1 - 0.13 12.9 0.1 0.3 11.7 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DYW_deaminase PF14432.6 KPA40768.1 - 0.16 11.8 5.5 0.81 9.6 0.5 2.1 2 0 0 2 2 2 0 DYW family of nucleic acid deaminases PCMT PF01135.19 KPA40770.1 - 2.3e-52 177.8 0.0 3e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KPA40770.1 - 2.2e-05 24.3 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KPA40770.1 - 6.9e-05 22.9 0.0 9.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40770.1 - 0.0027 18.4 0.0 0.0045 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KPA40770.1 - 0.0073 15.5 0.0 0.22 10.7 0.0 2.0 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.6 KPA40770.1 - 0.034 14.0 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KPA40770.1 - 0.039 13.3 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPA40770.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KPA40770.1 - 0.11 13.2 0.0 0.19 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2370 PF10176.9 KPA40771.1 - 5.8e-88 294.3 0.0 2.2e-87 292.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) RAP1 PF07218.11 KPA40771.1 - 0.13 10.5 0.5 0.17 10.1 0.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mito_carr PF00153.27 KPA40773.1 - 6.7e-52 173.4 4.2 1.7e-22 79.2 0.4 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Goodbye PF17109.5 KPA40775.1 - 9e-31 106.8 0.1 4.7e-30 104.5 0.1 2.3 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain TPR_1 PF00515.28 KPA40775.1 - 7.5e-10 38.2 2.5 0.012 15.4 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPA40775.1 - 9.6e-10 37.8 3.6 0.0085 16.1 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 KPA40775.1 - 5.1e-08 33.5 0.5 4.9e-07 30.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain TPR_19 PF14559.6 KPA40775.1 - 9.5e-05 22.8 3.1 0.00097 19.6 0.1 3.9 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA40775.1 - 0.00012 22.0 0.8 0.53 10.6 0.0 5.0 4 0 0 4 4 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 KPA40775.1 - 0.00032 21.0 0.0 0.0014 18.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.6 KPA40775.1 - 0.00036 20.8 7.7 0.54 10.6 0.1 5.2 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPA40775.1 - 0.00083 19.2 4.7 7.6 6.8 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA40775.1 - 0.0029 17.8 1.3 0.086 13.1 1.3 3.1 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KPA40775.1 - 0.005 17.5 2.4 0.45 11.5 0.0 5.1 5 1 1 6 6 4 1 Tetratricopeptide repeat NACHT PF05729.12 KPA40775.1 - 0.01 15.8 0.0 0.22 11.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 KPA40775.1 - 0.015 15.3 0.0 0.13 12.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain Turandot PF07240.11 KPA40775.1 - 0.025 14.6 0.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot AAA_28 PF13521.6 KPA40775.1 - 0.03 14.5 0.1 0.36 11.0 0.0 2.8 2 1 1 3 3 2 0 AAA domain C1_1 PF00130.22 KPA40775.1 - 0.035 14.0 0.5 0.082 12.8 0.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPR_17 PF13431.6 KPA40775.1 - 0.062 13.7 0.4 0.42 11.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 KPA40775.1 - 0.069 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein PPR_long PF17177.4 KPA40775.1 - 0.079 12.3 0.9 2.8 7.2 0.0 3.1 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP AAA_18 PF13238.6 KPA40775.1 - 0.083 13.4 0.0 2.7 8.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KPA40775.1 - 0.098 13.0 0.0 0.34 11.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase TPR_11 PF13414.6 KPA40775.1 - 0.12 12.1 0.0 0.39 10.4 0.0 1.9 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.6 KPA40775.1 - 0.14 12.8 0.2 1.3 9.7 0.0 2.7 4 0 0 4 4 2 0 Tetratricopeptide repeat DUF148 PF02520.17 KPA40775.1 - 0.43 10.7 1.8 21 5.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF148 NAD_binding_10 PF13460.6 KPA40776.1 - 1.2e-12 48.2 0.0 2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPA40776.1 - 2.6e-11 43.5 0.1 2.1e-10 40.6 0.1 2.2 1 1 0 1 1 1 1 NmrA-like family DFP PF04127.15 KPA40776.1 - 0.026 14.3 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.19 KPA40776.1 - 0.16 11.2 0.2 0.44 9.9 0.0 1.8 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_23 PF13489.6 KPA40777.1 - 1.6e-13 50.8 0.0 2.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA40777.1 - 5.9e-09 36.5 0.0 1.6e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA40777.1 - 2.7e-07 30.5 0.0 2.3e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA40777.1 - 3.7e-06 27.5 0.0 7.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA40777.1 - 2.6e-05 24.9 0.0 0.00019 22.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KPA40777.1 - 4.7e-05 23.6 0.0 6.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KPA40777.1 - 0.00099 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KPA40777.1 - 0.0035 16.9 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KPA40777.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KPA40777.1 - 0.02 14.6 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase DUF3602 PF12223.8 KPA40779.1 - 1.6e-09 38.2 10.6 9e-05 23.0 3.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Abhydrolase_4 PF08386.10 KPA40780.1 - 5e-21 74.8 0.0 1.1e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KPA40780.1 - 2.3e-20 73.3 0.0 6.2e-20 71.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ribosomal_L24e PF01246.20 KPA40781.1 - 4.1e-31 107.0 6.1 7.8e-31 106.1 6.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e DUF5078 PF16877.5 KPA40781.1 - 0.027 14.9 0.3 0.052 14.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) TFIIA PF03153.13 KPA40781.1 - 0.16 11.9 9.2 0.17 11.8 9.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 KPA40781.1 - 0.22 11.3 18.4 0.37 10.5 18.4 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3295 PF11702.8 KPA40781.1 - 0.23 10.8 7.5 0.25 10.6 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Pam16 PF03656.13 KPA40782.1 - 1.8e-06 28.0 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 KPA40782.1 - 3.1e-05 24.0 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DNA_pol_A_exo1 PF01612.20 KPA40783.1 - 0.01 15.6 0.0 0.029 14.1 0.0 1.8 1 1 0 1 1 1 0 3'-5' exonuclease Ku_PK_bind PF08785.11 KPA40784.1 - 3.3e-38 130.5 0.0 6.5e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KPA40784.1 - 9.3e-29 100.6 0.0 1.8e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KPA40784.1 - 1.9e-14 54.0 0.0 4.6e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KPA40784.1 - 0.00034 20.9 0.0 0.00083 19.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4149 PF13664.6 KPA40785.1 - 1.1e-22 80.3 2.0 1.1e-22 80.3 2.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Hydrolase_6 PF13344.6 KPA40787.1 - 2.5e-30 104.6 0.0 3.8e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA40787.1 - 3.9e-15 56.7 0.0 3e-07 30.9 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA40787.1 - 5.5e-15 55.2 0.0 2.4e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 KPA40787.1 - 9.4e-05 22.6 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 KPA40787.1 - 0.19 11.2 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DUF1295 PF06966.12 KPA40788.1 - 4.2e-24 85.4 8.0 1.4e-23 83.7 8.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KPA40788.1 - 0.053 14.0 0.2 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.20 KPA40789.1 - 8.1e-103 344.6 0.0 1.4e-97 327.3 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 KPA40789.1 - 9e-17 61.2 0.0 1.8e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Toprim domain CHASE5 PF17149.4 KPA40789.1 - 0.2 11.6 0.0 0.5 10.3 0.0 1.6 1 0 0 1 1 1 0 Periplasmic sensor domain found in signal transduction proteins Stb3 PF10330.9 KPA40790.1 - 3.1e-38 129.7 0.0 8.1e-38 128.4 0.0 1.7 1 0 0 1 1 1 1 Putative Sin3 binding protein SF1-HH PF16275.5 KPA40790.1 - 0.033 14.5 0.2 0.07 13.5 0.2 1.5 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain zf-C2H2 PF00096.26 KPA40791.1 - 3e-07 30.5 17.2 1.9e-05 24.8 3.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPA40791.1 - 3.9e-05 23.9 7.4 7.5e-05 23.0 4.2 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPA40791.1 - 4.8e-05 23.8 2.5 4.8e-05 23.8 2.5 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA40791.1 - 0.00025 21.2 1.1 0.00072 19.8 1.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KPA40791.1 - 0.00028 21.1 3.6 0.00065 19.9 3.6 1.6 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KPA40791.1 - 0.015 15.3 2.3 0.033 14.2 2.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 KPA40791.1 - 0.053 13.9 1.2 0.15 12.5 0.8 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KPA40791.1 - 0.61 10.4 4.1 2.9 8.3 4.2 2.0 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.18 KPA40791.1 - 0.67 10.7 7.3 0.1 13.3 3.3 1.7 2 0 0 2 2 1 0 TRAF-type zinc finger zf-C2HE PF16278.5 KPA40791.1 - 1.9 9.0 4.6 5.7 7.5 4.5 1.9 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 KPA40791.1 - 2 8.4 5.7 0.62 10.0 1.8 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Macoilin PF09726.9 KPA40791.1 - 2.9 6.3 5.4 5.2 5.5 5.4 1.3 1 0 0 1 1 1 0 Macoilin family Spt20 PF12090.8 KPA40791.1 - 5.7 6.5 18.0 11 5.6 18.0 1.3 1 0 0 1 1 1 0 Spt20 family WD40 PF00400.32 KPA40794.1 - 2.1e-08 34.7 2.3 0.00028 21.6 0.1 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA40794.1 - 0.00094 19.4 0.4 0.33 11.3 0.1 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain zinc_ribbon_16 PF17034.5 KPA40794.1 - 0.077 13.2 3.8 0.17 12.1 3.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family Ribosomal_L37ae PF01780.19 KPA40794.1 - 0.18 11.9 0.6 0.55 10.3 0.6 1.8 1 0 0 1 1 1 0 Ribosomal L37ae protein family DUF4379 PF14311.6 KPA40794.1 - 4.6 7.7 9.2 2.5 8.6 1.5 3.2 2 1 0 2 2 2 0 Probable Zinc-ribbon domain AAA_12 PF13087.6 KPA40797.1 - 1.2e-10 41.4 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thiamine_BP PF01910.17 KPA40798.1 - 6.2e-33 112.6 0.4 7.1e-33 112.4 0.4 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Polysacc_deac_1 PF01522.21 KPA40798.1 - 0.0038 17.1 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase CDC37_N PF03234.14 KPA40800.1 - 4e-49 166.8 0.9 4e-49 166.8 0.9 3.9 5 0 0 5 5 5 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KPA40800.1 - 4.7e-39 133.0 0.5 1.8e-38 131.1 0.2 2.1 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KPA40800.1 - 4.2e-35 119.9 4.3 4.2e-35 119.9 4.3 2.7 2 1 0 2 2 2 1 Cdc37 C terminal domain PhoU PF01895.19 KPA40800.1 - 1.3 9.5 5.9 0.84 10.1 0.5 3.0 3 0 0 3 3 3 0 PhoU domain NDUF_B5 PF09781.9 KPA40800.1 - 9.7 5.7 6.8 0.93 9.0 0.7 2.4 2 1 1 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit PHD PF00628.29 KPA40801.1 - 0.00067 19.5 3.6 0.00067 19.5 3.6 2.3 1 1 1 2 2 2 1 PHD-finger ING PF12998.7 KPA40801.1 - 0.0056 17.2 1.0 0.014 15.9 0.0 2.2 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding ThiD2 PF17792.1 KPA40801.1 - 0.057 13.9 4.5 4.9 7.6 0.0 3.2 3 0 0 3 3 3 0 ThiD2 family EF-hand_4 PF12763.7 KPA40801.1 - 0.11 12.5 0.0 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand NTP_transf_7 PF07984.12 KPA40801.1 - 0.26 10.5 0.0 0.39 9.9 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyltransferase TipE PF16972.5 KPA40801.1 - 0.37 9.9 7.1 0.5 9.5 6.1 1.7 2 0 0 2 2 2 0 Na+ channel auxiliary subunit TipE Bactofilin PF04519.13 KPA40802.1 - 1.8e-05 24.9 2.9 4.7e-05 23.6 1.6 2.0 1 1 1 2 2 2 1 Polymer-forming cytoskeletal FapA PF03961.13 KPA40802.1 - 0.00012 20.9 4.8 0.002 16.8 4.8 2.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A MinC_C PF03775.16 KPA40802.1 - 0.00074 19.5 5.9 0.01 15.8 0.3 3.3 1 1 4 5 5 5 2 Septum formation inhibitor MinC, C-terminal domain zf-C2H2 PF00096.26 KPA40804.1 - 0.018 15.5 3.3 0.047 14.2 3.3 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-BED PF02892.15 KPA40804.1 - 0.17 11.9 1.9 0.32 11.0 1.9 1.4 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_2 PF13465.6 KPA40804.1 - 0.45 11.0 2.4 8.3 7.0 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain SAPS PF04499.15 KPA40805.1 - 2.9e-192 639.8 1.6 2.9e-192 639.8 1.6 3.4 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Ndc1_Nup PF09531.10 KPA40805.1 - 8.9 4.9 7.3 17 3.9 7.3 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GCFC PF07842.12 KPA40806.1 - 1.3e-65 221.8 4.0 1.3e-65 221.8 4.0 1.6 1 1 1 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KPA40806.1 - 5.4e-14 51.8 3.4 5.4e-14 51.8 3.4 2.0 2 0 0 2 2 2 1 G-patch domain TIP_N PF12457.8 KPA40806.1 - 6e-13 49.1 10.1 6e-13 49.1 10.1 3.3 3 1 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 KPA40806.1 - 1.8e-07 31.1 2.6 1.8e-07 31.1 2.6 2.8 4 0 0 4 4 4 1 G-patch domain ATP-synt_E PF05680.12 KPA40806.1 - 2.2 8.7 6.6 3.7 8.0 4.8 2.4 2 0 0 2 2 2 0 ATP synthase E chain Peptidase_S8 PF00082.22 KPA40807.1 - 9.6e-34 117.0 11.9 1.6e-33 116.3 11.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KPA40807.1 - 4.2e-13 49.8 0.0 9e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 CLASP_N PF12348.8 KPA40808.1 - 1.6e-07 31.2 0.1 2.8e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.7 KPA40808.1 - 8e-05 22.7 0.4 0.00032 20.8 0.1 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KPA40808.1 - 0.0015 18.9 1.0 10 6.6 0.1 4.3 3 2 1 4 4 4 0 HEAT repeats HALZ PF02183.18 KPA40808.1 - 0.0045 17.2 8.5 0.05 13.8 0.4 3.1 3 0 0 3 3 2 1 Homeobox associated leucine zipper Syntaxin PF00804.25 KPA40808.1 - 0.017 14.8 4.5 0.05 13.3 4.5 1.8 1 0 0 1 1 1 0 Syntaxin Jnk-SapK_ap_N PF09744.9 KPA40808.1 - 0.065 13.5 11.0 0.2 11.8 11.0 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TAN PF11640.8 KPA40808.1 - 0.066 13.3 0.1 0.066 13.3 0.1 2.4 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair APC_N_CC PF16689.5 KPA40808.1 - 0.072 13.2 4.8 1.9 8.6 0.3 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF5082 PF16888.5 KPA40808.1 - 0.081 13.2 5.3 0.2 12.0 5.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Prefoldin PF02996.17 KPA40808.1 - 0.091 12.7 1.9 6.6 6.7 0.7 2.7 2 0 0 2 2 2 0 Prefoldin subunit HEAT PF02985.22 KPA40808.1 - 0.12 12.7 2.4 20 5.8 0.3 4.7 6 0 0 6 6 3 0 HEAT repeat SHE3 PF17078.5 KPA40808.1 - 0.17 11.6 9.3 0.35 10.5 9.3 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 CCDC144C PF14915.6 KPA40808.1 - 0.22 10.6 11.7 0.42 9.7 11.7 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Golgin_A5 PF09787.9 KPA40808.1 - 0.38 10.2 8.5 0.77 9.2 8.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 KLRAQ PF10205.9 KPA40808.1 - 0.72 10.1 9.3 15 5.9 3.7 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein SNARE PF05739.19 KPA40808.1 - 1.2 9.2 2.8 6.3 6.9 0.3 2.3 2 0 0 2 2 2 0 SNARE domain MCC-bdg_PDZ PF10506.9 KPA40808.1 - 1.4 9.0 11.0 0.33 11.0 1.7 4.1 4 1 0 4 4 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome YabA PF06156.13 KPA40808.1 - 2.1 9.0 7.8 29 5.4 7.8 2.6 1 1 0 1 1 1 0 Initiation control protein YabA Atg14 PF10186.9 KPA40808.1 - 2.3 7.2 5.0 5.5 6.0 5.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1640 PF07798.11 KPA40808.1 - 2.4 8.2 16.5 11 6.0 12.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Fez1 PF06818.15 KPA40808.1 - 3 8.3 12.2 0.43 11.0 7.6 1.9 2 0 0 2 2 1 0 Fez1 HAUS-augmin3 PF14932.6 KPA40808.1 - 3.1 7.3 7.7 31 4.0 7.3 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Cep57_CLD_2 PF14197.6 KPA40808.1 - 3.3 7.9 12.6 5.8 7.1 2.8 2.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF724 PF05266.14 KPA40808.1 - 3.4 7.4 8.6 8.1 6.2 8.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CASP_C PF08172.12 KPA40808.1 - 4.4 6.6 9.6 9.5 5.5 1.4 2.3 1 1 0 2 2 2 0 CASP C terminal Cnn_1N PF07989.11 KPA40808.1 - 5.2 7.3 8.8 23 5.2 1.1 3.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 ADIP PF11559.8 KPA40808.1 - 5.6 7.0 12.2 17 5.4 12.2 1.9 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KPA40808.1 - 7.3 5.8 10.1 1.1 8.5 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cluap1 PF10234.9 KPA40808.1 - 9.5 5.5 10.1 24 4.2 10.1 1.6 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF3429 PF11911.8 KPA40809.1 - 4.7e-45 153.4 6.2 6e-45 153.1 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) SHR-BD PF06650.12 KPA40810.1 - 9.2e-94 313.8 0.0 1.5e-91 306.5 0.0 3.1 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KPA40810.1 - 2.4e-92 308.6 17.7 8.6e-90 300.3 2.5 6.0 6 0 0 6 6 6 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KPA40810.1 - 1.4e-88 296.7 1.0 6.5e-86 288.0 0.0 3.7 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KPA40810.1 - 7.1e-72 240.9 7.5 9e-68 227.5 1.3 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KPA40810.1 - 9.9e-40 135.3 0.0 3.7e-39 133.4 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KPA40810.1 - 4.1e-06 27.1 0.0 1.4e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain AP4E_app_platf PF14807.6 KPA40810.1 - 0.12 12.7 0.1 0.43 11.0 0.1 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Nucleos_tra2_C PF07662.13 KPA40811.1 - 4.7e-69 232.4 0.9 4.7e-69 232.4 0.9 2.2 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KPA40811.1 - 2.7e-25 88.8 3.0 3e-24 85.4 1.0 3.3 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus DUF2985 PF11204.8 KPA40812.1 - 1.4e-21 76.4 2.2 2.8e-21 75.4 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Peptidase_S49_N PF08496.10 KPA40812.1 - 0.02 15.0 1.8 0.02 15.0 1.8 1.9 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Aconitase PF00330.20 KPA40812.1 - 0.15 11.0 0.1 0.31 10.0 0.0 1.5 1 1 0 1 1 1 0 Aconitase family (aconitate hydratase) HSP70 PF00012.20 KPA40812.1 - 0.15 10.2 4.2 0.22 9.7 4.2 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF2098 PF09871.9 KPA40812.1 - 3.6 8.0 10.3 10 6.5 10.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Fungal_trans PF04082.18 KPA40813.1 - 9.7e-12 44.5 0.3 1.4e-11 44.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA40813.1 - 3e-06 27.3 8.4 5.5e-06 26.4 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 KPA40814.1 - 6.8e-91 304.9 0.0 8.3e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III VCBS PF13517.6 KPA40816.1 - 9.8e-30 102.9 53.8 4.7e-12 46.3 5.7 8.4 3 2 5 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KPA40816.1 - 1.1e-27 97.6 1.4 7.5e-16 59.0 0.2 2.5 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA40816.1 - 2.4e-17 63.6 1.0 9.6e-10 38.8 0.2 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 KPA40816.1 - 0.00063 19.2 4.9 8.9 5.6 0.0 5.8 5 2 1 6 6 6 2 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.6 KPA40816.1 - 0.032 14.4 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 KPA40816.1 - 0.4 10.8 29.7 0.57 10.4 0.8 5.4 5 0 0 5 5 5 0 FG-GAP repeat zf-ACC PF17848.1 KPA40817.1 - 0.15 12.2 0.2 0.27 11.3 0.2 1.4 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain DUF3829 PF12889.7 KPA40818.1 - 0.37 10.2 3.4 0.25 10.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Seryl_tRNA_N PF02403.22 KPA40818.1 - 0.87 9.9 6.2 0.74 10.1 0.6 3.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 KPA40819.1 - 3.4e-18 66.0 0.0 5.8e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40819.1 - 6.9e-14 51.8 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPA40819.1 - 0.0034 16.2 0.0 0.0051 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Raptor_N PF14538.6 KPA40820.1 - 0.0034 17.3 0.0 0.0076 16.2 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Pkinase PF00069.25 KPA40820.1 - 0.063 12.6 0.0 0.24 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KPA40820.1 - 0.12 11.7 0.0 15 4.8 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase Cas1_AcylT PF07779.12 KPA40821.1 - 1.9e-59 201.9 18.2 4.5e-59 200.6 18.2 1.5 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p RRM_2 PF04059.12 KPA40823.1 - 1.4e-36 124.6 0.4 2.3e-36 123.9 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 Sad1_UNC PF07738.13 KPA40824.1 - 1e-31 109.7 0.0 1.9e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Mannosyl_trans3 PF11051.8 KPA40825.1 - 1.1e-39 136.4 0.0 4.5e-39 134.5 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative SUR7 PF06687.12 KPA40827.1 - 0.12 12.0 14.3 0.045 13.4 4.4 2.2 2 0 0 2 2 2 0 SUR7/PalI family Per1 PF04080.13 KPA40827.1 - 1.2 8.8 7.0 0.09 12.5 1.5 1.7 2 1 0 2 2 2 0 Per1-like family FtsK_4TM PF13491.6 KPA40827.1 - 2.6 7.7 7.4 3.1 7.5 0.1 2.9 3 0 0 3 3 3 0 4TM region of DNA translocase FtsK/SpoIIIE MHYT PF03707.16 KPA40827.1 - 8.1 6.7 8.0 14 6.0 0.7 3.7 4 0 0 4 4 4 0 Bacterial signalling protein N terminal repeat Methyltransf_2 PF00891.18 KPA40828.1 - 3.4e-20 72.3 0.0 4.7e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KPA40828.1 - 0.16 12.7 0.0 0.95 10.2 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Abhydrolase_1 PF00561.20 KPA40829.1 - 5.8e-13 49.1 0.0 6.6e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA40829.1 - 3.9e-10 39.4 0.0 4.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA40829.1 - 4.2e-06 27.5 0.0 5.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KPA40829.1 - 0.024 14.8 0.0 0.036 14.2 0.0 1.3 1 1 0 1 1 1 0 Thioesterase domain MOSC PF03473.17 KPA40830.1 - 1.8e-10 40.9 0.0 3.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 KPA40830.1 - 3.6e-06 26.8 0.5 7.2e-06 25.9 0.5 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 KPA40830.1 - 0.004 17.8 0.0 0.0094 16.6 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-UBR PF02207.20 KPA40832.1 - 2.6e-14 53.1 4.5 2.6e-14 53.1 4.5 3.2 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.23 KPA40833.1 - 1.8e-100 334.7 0.0 3.4e-100 333.7 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KPA40833.1 - 3.4e-39 133.6 0.1 6.4e-39 132.7 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KPA40833.1 - 8.3e-26 90.2 0.7 2.2e-25 88.9 0.7 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 KPA40833.1 - 3.9e-24 85.7 31.0 3.9e-24 85.7 31.0 2.3 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 KPA40833.1 - 3.2e-15 56.6 0.1 9e-15 55.1 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KPA40833.1 - 1e-07 31.6 0.1 2.8e-06 26.9 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KPA40833.1 - 3.9e-06 26.9 0.0 8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KPA40833.1 - 0.0038 17.1 0.1 0.019 14.8 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KPA40833.1 - 0.01 15.6 0.2 0.058 13.1 0.2 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 KPA40833.1 - 0.18 12.5 0.5 0.56 10.9 0.5 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-TFIIB PF13453.6 KPA40833.1 - 0.42 10.0 1.9 0.88 9.0 1.9 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger DUF4763 PF15960.5 KPA40834.1 - 0.0002 20.8 1.3 0.0002 20.8 1.3 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4763) APH PF01636.23 KPA40834.1 - 0.0072 16.3 2.5 0.011 15.7 2.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family SHE3 PF17078.5 KPA40834.1 - 0.03 14.0 5.8 0.056 13.2 5.8 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Carbam_trans_N PF02543.15 KPA40834.1 - 0.044 13.4 0.3 0.066 12.9 0.3 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus F_actin_bind PF08919.10 KPA40834.1 - 0.064 13.4 0.9 0.14 12.2 0.9 1.5 1 0 0 1 1 1 0 F-actin binding DUF489 PF04356.12 KPA40834.1 - 0.098 12.7 2.1 1.7 8.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF489) p47_phox_C PF08944.11 KPA40834.1 - 0.12 11.8 0.9 0.22 10.9 0.9 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Spore_III_AB PF09548.10 KPA40834.1 - 0.26 11.4 4.2 0.88 9.7 0.1 2.7 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Bacillus_HBL PF05791.11 KPA40834.1 - 0.26 11.1 5.3 0.5 10.2 0.9 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TolA_bind_tri PF16331.5 KPA40834.1 - 0.28 11.3 4.7 11 6.2 0.1 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation GAS PF13851.6 KPA40834.1 - 0.54 9.6 10.2 0.23 10.8 5.5 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.6 KPA40834.1 - 0.62 10.1 20.7 0.13 12.3 16.7 1.9 2 1 0 2 2 1 0 Ciliary rootlet component, centrosome cohesion THOC7 PF05615.13 KPA40834.1 - 0.64 10.3 12.9 3.6 7.9 12.9 2.2 1 1 0 1 1 1 0 Tho complex subunit 7 DUF724 PF05266.14 KPA40834.1 - 0.97 9.2 5.6 1.1 9.0 3.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Phage_lysis PF03245.13 KPA40834.1 - 1.2 9.3 11.7 0.32 11.1 0.8 3.3 2 1 2 4 4 3 0 Bacteriophage Rz lysis protein TMPIT PF07851.13 KPA40834.1 - 1.3 8.2 5.9 3.2 6.9 1.6 2.1 1 1 0 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.10 KPA40834.1 - 1.4 9.1 6.4 2.8 8.1 3.6 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 KPA40834.1 - 1.4 8.4 9.6 5.5 6.5 9.6 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit SOGA PF11365.8 KPA40834.1 - 1.5 10.0 8.6 0.6 11.3 2.5 3.1 2 2 0 2 2 2 0 Protein SOGA LMBR1 PF04791.16 KPA40834.1 - 2.9 6.7 4.7 4.1 6.2 4.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 KPA40834.1 - 3.8 8.0 17.6 0.38 11.3 8.5 2.8 2 1 1 3 3 3 0 Apg6 coiled-coil region NifU_N PF01592.16 KPA40836.1 - 4e-54 182.2 0.0 5.1e-54 181.9 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain bMG5 PF17972.1 KPA40836.1 - 0.054 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain RPE65 PF03055.15 KPA40837.1 - 9.3e-113 377.9 0.0 1.1e-112 377.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein STAS PF01740.21 KPA40837.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 STAS domain FTA4 PF13093.6 KPA40838.1 - 2.1e-63 213.8 0.1 2.7e-63 213.5 0.1 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 NOPS PF08075.11 KPA40838.1 - 0.082 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 NOPS (NUC059) domain DUF2306 PF10067.9 KPA40839.1 - 2.1e-12 47.5 13.1 2.1e-12 47.5 13.1 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) GFO_IDH_MocA PF01408.22 KPA40840.1 - 3.6e-19 69.7 0.0 7.3e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPA40840.1 - 3.1e-07 30.4 0.1 7.7e-07 29.1 0.0 1.6 1 1 1 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain THF_DHG_CYH PF00763.23 KPA40840.1 - 0.086 13.1 0.0 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 4HBT_2 PF13279.6 KPA40841.1 - 4e-06 27.3 0.1 5.6e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KPA40841.1 - 1.4e-05 24.5 0.4 2.6e-05 23.6 0.4 1.4 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT PF03061.22 KPA40841.1 - 0.00036 20.8 0.0 0.00054 20.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily PseudoU_synth_2 PF00849.22 KPA40842.1 - 1.9e-29 102.8 0.0 3.6e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase FHA PF00498.26 KPA40842.1 - 0.039 14.3 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 FHA domain Ub-Mut7C PF14451.6 KPA40842.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin DUF3425 PF11905.8 KPA40843.1 - 1.1e-14 54.5 0.1 1.9e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KPA40843.1 - 0.21 11.7 16.9 2.9 8.0 14.4 2.3 1 1 1 2 2 2 0 bZIP transcription factor SPX PF03105.19 KPA40843.1 - 1.6 8.6 11.7 0.038 13.9 5.3 1.4 2 0 0 2 2 2 0 SPX domain DUF4337 PF14235.6 KPA40843.1 - 2.3 8.3 4.1 3.8 7.6 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Macoilin PF09726.9 KPA40843.1 - 4.1 5.9 6.9 6.4 5.2 6.9 1.2 1 0 0 1 1 1 0 Macoilin family HALZ PF02183.18 KPA40843.1 - 4.7 7.5 8.2 3 8.1 1.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper SR-25 PF10500.9 KPA40844.1 - 0.0097 15.5 0.7 0.017 14.7 0.7 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein zf-C2H2 PF00096.26 KPA40845.1 - 2.6e-06 27.6 8.5 0.011 16.2 1.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA40845.1 - 8.3e-05 23.1 6.9 0.17 12.8 1.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KPA40845.1 - 0.034 14.8 0.5 0.076 13.6 0.5 1.6 1 0 0 1 1 1 0 FOXP coiled-coil domain IBR PF01485.21 KPA40845.1 - 0.042 14.1 0.4 0.1 12.8 0.4 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-H2C2_2 PF13465.6 KPA40845.1 - 0.44 11.1 11.7 0.093 13.2 1.6 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Nucleotid_trans PF03407.16 KPA40846.1 - 3.1e-07 30.6 0.1 1.8e-06 28.1 0.1 1.9 1 1 1 2 2 2 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 KPA40846.1 - 9.2e-07 28.8 3.4 3e-06 27.2 3.4 1.7 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KPA40846.1 - 0.017 14.7 0.3 0.054 13.1 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF273 MFS_1 PF07690.16 KPA40847.1 - 2.4e-33 115.6 38.4 2.4e-33 115.6 38.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA40847.1 - 1.2e-09 37.6 2.7 1.2e-09 37.6 2.7 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter RELT PF12606.8 KPA40847.1 - 0.32 10.0 4.0 0.79 8.8 2.5 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 BatA PF07584.11 KPA40847.1 - 1 9.8 6.6 11 6.5 0.2 3.9 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal Pyrophosphatase PF00719.19 KPA40848.1 - 1.9e-45 154.6 0.1 2.6e-45 154.1 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Glyco_hydro_10 PF00331.20 KPA40851.1 - 4.8e-103 344.6 0.0 6.4e-103 344.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KPA40851.1 - 2.8e-12 46.4 4.9 6.8e-12 45.1 4.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain PAPS_reduct PF01507.19 KPA40852.1 - 3e-27 95.8 0.0 1.3e-19 70.9 0.0 2.4 2 1 1 3 3 3 2 Phosphoadenosine phosphosulfate reductase family F-box-like PF12937.7 KPA40854.1 - 0.052 13.4 0.1 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 F-box-like PHO4 PF01384.20 KPA40855.1 - 4.6e-116 387.6 9.2 5.3e-116 387.3 9.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF1674 PF07896.12 KPA40856.1 - 1.2e-16 60.9 7.6 2.8e-16 59.7 7.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Rxt3 PF08642.10 KPA40857.1 - 1.1e-40 139.3 1.3 3.1e-40 137.9 0.0 2.3 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KPA40857.1 - 2.5e-05 24.3 0.0 0.00066 19.7 0.0 2.4 2 0 0 2 2 2 1 LCCL domain CTP_transf_like PF01467.26 KPA40858.1 - 1.3e-06 28.7 0.1 1.2e-05 25.5 0.1 2.4 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KPA40858.1 - 0.061 13.2 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase Glyoxalase PF00903.25 KPA40861.1 - 0.0011 19.2 0.2 0.0022 18.2 0.2 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cu-oxidase_3 PF07732.15 KPA40862.1 - 7.4e-42 142.1 4.9 1.4e-41 141.2 0.8 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KPA40862.1 - 1.7e-31 108.8 7.3 8.6e-26 90.3 0.3 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KPA40862.1 - 1.3e-14 54.6 0.1 3.2e-10 40.3 0.1 3.2 3 0 0 3 3 3 3 Multicopper oxidase AA_permease PF00324.21 KPA40863.1 - 5.3e-133 444.1 36.8 6e-133 443.9 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA40863.1 - 6.9e-37 127.3 43.3 8.2e-37 127.0 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease 2OG-FeII_Oxy_3 PF13640.6 KPA40864.1 - 4.6e-10 40.3 0.0 8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 KPA40864.1 - 0.014 15.7 0.0 0.085 13.1 0.0 2.1 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) OB_NTP_bind PF07717.16 KPA40865.1 - 1.1e-21 77.0 0.0 2.3e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KPA40865.1 - 2.2e-17 63.3 0.0 2.2e-17 63.3 0.0 4.0 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KPA40865.1 - 9.9e-15 54.9 0.0 3e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPA40865.1 - 1.7e-05 24.7 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KPA40865.1 - 9e-05 22.8 0.0 9e-05 22.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPA40865.1 - 0.00049 19.9 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KPA40865.1 - 0.0025 16.9 0.0 0.0059 15.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 KPA40865.1 - 0.0032 17.1 0.2 0.0096 15.6 0.2 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KPA40865.1 - 0.014 15.7 0.1 0.034 14.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KPA40865.1 - 0.18 11.4 0.3 1.5 8.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KPA40865.1 - 0.31 11.6 0.0 0.31 11.6 0.0 2.6 3 1 0 3 3 3 0 ABC transporter DnaJ_C PF01556.18 KPA40866.1 - 2.9e-29 102.0 0.0 4.5e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KPA40866.1 - 3.6e-25 87.9 2.3 5.7e-25 87.2 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KPA40866.1 - 1.4e-14 54.2 17.8 2.3e-14 53.5 17.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KPA40866.1 - 0.018 15.0 7.0 0.64 10.1 0.3 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KPA40866.1 - 0.033 14.1 8.6 0.12 12.4 1.7 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF4235 PF14019.6 KPA40867.1 - 0.12 12.5 0.0 0.12 12.5 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4235) COPIIcoated_ERV PF07970.12 KPA40868.1 - 4.2e-37 128.2 0.0 6.1e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KPA40868.1 - 2.5e-24 85.4 0.0 4.9e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CFEM PF05730.11 KPA40870.1 - 4.1e-15 55.6 13.3 7.6e-15 54.8 13.3 1.5 1 0 0 1 1 1 1 CFEM domain Sugar_tr PF00083.24 KPA40871.1 - 7.5e-86 288.8 23.1 8.9e-86 288.5 23.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA40871.1 - 1.7e-26 93.0 24.5 1.7e-26 93.0 24.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PEPCK_ATP PF01293.20 KPA40871.1 - 0.1 11.2 0.2 0.2 10.3 0.1 1.4 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase Mannosidase_ig PF17786.1 KPA40872.1 - 5.9e-17 62.1 0.0 1.5e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KPA40872.1 - 8.7e-08 32.8 0.0 2.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KPA40872.1 - 0.0014 17.9 0.3 0.0037 16.4 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Fungal_trans PF04082.18 KPA40873.1 - 3.4e-18 65.6 0.3 8.6e-18 64.3 0.3 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA40873.1 - 0.00012 22.1 10.0 0.00024 21.2 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_Mga PF08280.11 KPA40873.1 - 0.14 12.2 0.3 0.83 9.7 0.0 2.5 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Cellulase PF00150.18 KPA40874.1 - 9.6e-17 61.3 2.4 1.4e-16 60.8 2.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sporozoite_P67 PF05642.11 KPA40875.1 - 0.36 8.9 10.5 0.47 8.5 10.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PARM PF17061.5 KPA40875.1 - 3.8 7.6 18.5 5.3 7.1 18.5 1.2 1 0 0 1 1 1 0 PARM Peptidase_S10 PF00450.22 KPA40877.1 - 1.5e-79 268.4 0.9 2.6e-79 267.6 0.9 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 KPA40877.1 - 0.0018 17.8 0.1 0.0088 15.5 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Toxin_trans PF07952.12 KPA40877.1 - 0.048 12.8 0.1 0.085 11.9 0.1 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain OCRE PF17780.1 KPA40877.1 - 0.48 10.5 4.5 15 5.7 0.6 2.6 2 0 0 2 2 2 0 OCRE domain CRT-like PF08627.10 KPA40878.1 - 0.034 13.1 0.0 0.041 12.8 0.0 1.0 1 0 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like GST_N_3 PF13417.6 KPA40879.1 - 5.1e-15 55.6 0.0 8.8e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPA40879.1 - 1.5e-12 47.7 0.0 2.3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPA40879.1 - 7.5e-11 42.2 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPA40879.1 - 2.3e-06 27.5 0.0 4.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA40879.1 - 0.00015 21.9 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA40879.1 - 0.001 19.2 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KPA40879.1 - 0.057 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C_4 PF14834.6 KPA40879.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tetraspanin PF00335.20 KPA40880.1 - 0.025 14.3 0.7 0.036 13.8 0.7 1.5 1 1 0 1 1 1 0 Tetraspanin family CoA_binding_3 PF13727.6 KPA40880.1 - 0.031 14.3 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 CoA-binding domain His_Phos_1 PF00300.22 KPA40881.1 - 9.9e-06 25.4 0.0 1.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RTA1 PF04479.13 KPA40882.1 - 4.2e-43 147.4 8.8 5.4e-43 147.0 8.8 1.1 1 0 0 1 1 1 1 RTA1 like protein DctQ PF04290.12 KPA40882.1 - 0.028 14.3 4.1 0.053 13.4 4.1 1.6 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component F-box-like PF12937.7 KPA40883.1 - 8.6e-06 25.6 0.1 1.9e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like GnRH PF00446.17 KPA40883.1 - 0.1 13.0 0.3 0.26 11.8 0.3 1.7 1 0 0 1 1 1 0 Gonadotropin-releasing hormone Arylsulfotran_2 PF14269.6 KPA40884.1 - 2.4e-61 207.7 0.2 3.4e-61 207.2 0.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KPA40884.1 - 6.3e-09 35.2 0.1 3e-08 33.0 0.1 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) tRNA-synt_2 PF00152.20 KPA40885.1 - 5.1e-66 222.9 0.0 6.5e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KPA40885.1 - 0.00042 20.3 0.0 0.00091 19.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1501 PF07394.12 KPA40885.1 - 0.027 13.5 0.2 0.043 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) FinO_N PF12602.8 KPA40885.1 - 5.7 7.3 11.6 15 6.0 11.6 1.8 1 1 0 1 1 1 0 Fertility inhibition protein N terminal DUF1989 PF09347.10 KPA40886.1 - 1.3e-59 200.6 0.0 1.6e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Chromo PF00385.24 KPA40888.1 - 3.6e-10 39.6 8.6 6.2e-08 32.4 1.0 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Pro_CA PF00484.19 KPA40889.1 - 4.8e-49 166.6 0.1 1.1e-48 165.5 0.0 1.6 2 0 0 2 2 2 1 Carbonic anhydrase PNP_UDP_1 PF01048.20 KPA40889.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphorylase superfamily GAS PF13851.6 KPA40890.1 - 0.00024 20.5 14.8 0.0014 18.0 6.8 3.2 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding CathepsinC_exc PF08773.11 KPA40890.1 - 0.013 15.8 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 Cathepsin C exclusion domain Prefoldin_3 PF13758.6 KPA40890.1 - 0.091 12.8 1.7 0.33 11.0 0.8 2.4 1 1 1 2 2 2 0 Prefoldin subunit zf-C4H2 PF10146.9 KPA40890.1 - 0.94 9.7 12.8 0.11 12.8 6.7 2.3 2 1 0 2 2 2 0 Zinc finger-containing protein AP2 PF00847.20 KPA40890.1 - 6.8 7.0 9.2 24 5.2 0.1 3.4 3 0 0 3 3 3 0 AP2 domain FadA PF09403.10 KPA40890.1 - 9.7 6.8 14.5 0.63 10.6 8.3 2.1 2 0 0 2 2 2 0 Adhesion protein FadA MMR_HSR1 PF01926.23 KPA40892.1 - 2.7e-05 24.2 0.1 0.00017 21.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KPA40892.1 - 0.0035 16.6 0.0 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 Septin AAA_16 PF13191.6 KPA40892.1 - 0.0046 17.4 0.0 0.025 15.0 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KPA40892.1 - 0.0081 15.9 0.8 0.025 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KPA40892.1 - 0.01 16.3 1.0 0.1 13.1 0.0 2.9 3 0 0 3 3 3 0 ABC transporter IIGP PF05049.13 KPA40892.1 - 0.02 14.0 0.0 0.052 12.6 0.0 1.7 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 KPA40892.1 - 0.021 14.2 0.0 0.063 12.6 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KPA40892.1 - 0.023 14.6 0.0 0.078 12.9 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KPA40892.1 - 0.042 13.6 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KPA40892.1 - 0.048 13.9 0.1 0.31 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KPA40892.1 - 0.054 12.6 0.2 0.44 9.5 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein CENP-C_mid PF15620.6 KPA40892.1 - 0.092 12.7 0.1 0.092 12.7 0.1 2.5 3 1 0 3 3 2 0 Centromere assembly component CENP-C middle DNMT3B-binding region Roc PF08477.13 KPA40892.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATPase PF06745.13 KPA40892.1 - 0.13 11.5 3.3 8.1 5.7 1.7 2.8 2 1 0 3 3 3 0 KaiC ATP_bind_1 PF03029.17 KPA40892.1 - 0.16 11.8 0.0 0.92 9.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF445 PF04286.12 KPA40892.1 - 2.7 7.7 12.3 1.1 9.0 8.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF445) GIDA_assoc PF13932.6 KPA40892.1 - 3.6 7.7 10.3 30 4.7 7.1 3.4 4 0 0 4 4 4 0 GidA associated domain Dynamin_N PF00350.23 KPA40892.1 - 3.7 7.6 5.4 2.4 8.2 0.1 2.8 2 2 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 KPA40892.1 - 3.8 8.0 14.7 0.45 11.0 0.2 2.9 3 0 0 3 3 3 0 AAA domain Ifi-6-16 PF06140.13 KPA40894.1 - 2.7e-07 30.4 0.0 6.4e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Interferon-induced 6-16 family DUF4404 PF14357.6 KPA40894.1 - 7.5e-05 23.3 0.1 0.00012 22.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4404) Endonuc-BglII PF09195.11 KPA40894.1 - 0.037 13.9 0.0 0.048 13.5 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BglII DUF883 PF05957.13 KPA40894.1 - 0.051 14.2 1.5 0.12 13.0 1.5 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) G_glu_transpept PF01019.21 KPA40895.1 - 2.3e-144 482.0 0.0 2.6e-144 481.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HET PF06985.11 KPA40896.1 - 1.8e-30 106.2 0.1 2.8e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) S6PP_C PF08472.10 KPA40896.1 - 0.079 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal SAGA-Tad1 PF12767.7 KPA40897.1 - 0.92 9.2 7.3 11 5.6 7.5 2.1 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Glutaredoxin PF00462.24 KPA40898.1 - 2.9e-16 59.4 0.0 4.6e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Flavoprotein PF02441.19 KPA40899.1 - 1.3e-49 168.0 0.3 1.5e-49 167.7 0.3 1.1 1 0 0 1 1 1 1 Flavoprotein Nas2_N PF18265.1 KPA40900.1 - 0.0045 16.9 0.7 0.011 15.6 0.0 2.1 2 1 0 2 2 2 1 Nas2 N_terminal domain Apolipoprotein PF01442.18 KPA40900.1 - 0.037 13.9 7.7 0.17 11.8 2.1 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 KPA40900.1 - 0.37 11.1 3.1 8.6 6.7 0.1 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HisKA_3 PF07730.13 KPA40900.1 - 0.45 11.1 4.1 0.65 10.6 0.1 3.0 3 1 0 3 3 3 0 Histidine kinase CENP-H PF05837.12 KPA40900.1 - 0.75 10.2 7.3 3.8 8.0 0.8 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) HD_6 PF18019.1 KPA40900.1 - 3.5 7.7 5.3 14 5.7 0.5 2.3 1 1 0 2 2 2 0 HD domain YtxH PF12732.7 KPA40900.1 - 7.9 7.1 5.7 5.8 7.5 2.4 2.3 2 1 0 2 2 2 0 YtxH-like protein Aminotran_4 PF01063.19 KPA40901.1 - 1.4e-23 84.0 0.0 1.8e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV CTP_transf_like PF01467.26 KPA40902.1 - 5.5e-24 85.0 0.0 1.8e-20 73.6 0.0 3.2 3 0 0 3 3 3 3 Cytidylyltransferase-like DeoRC PF00455.22 KPA40902.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 DeoR C terminal sensor domain adh_short_C2 PF13561.6 KPA40903.1 - 1.5e-24 86.8 0.0 2.6e-24 86.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA40903.1 - 1.7e-23 83.1 0.0 2.1e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA40903.1 - 8.7e-10 38.8 0.1 1.3e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA40903.1 - 0.00011 21.5 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPA40903.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KPA40903.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IPU_b_solenoid PF18783.1 KPA40906.1 - 0.18 11.9 0.6 0.34 11.0 0.6 1.4 1 0 0 1 1 1 0 Isopullulanase beta-solenoid repeat Ribosomal_L1 PF00687.21 KPA40907.1 - 9.9e-66 221.4 2.8 2e-65 220.3 2.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family PLA2_B PF01735.18 KPA40907.1 - 0.018 13.5 0.0 0.028 12.9 0.0 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain CcmE PF03100.15 KPA40907.1 - 0.026 14.5 0.1 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 CcmE Palm_thioest PF02089.15 KPA40908.1 - 2.1e-77 260.2 0.0 2.7e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KPA40908.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) SCRL PF06876.12 KPA40908.1 - 0.62 10.3 6.8 1.3 9.3 1.7 3.0 3 0 0 3 3 3 0 Plant self-incompatibility response (SCRL) protein Cyclin_N PF00134.23 KPA40909.1 - 1.4e-06 28.0 0.6 3.7e-06 26.7 0.0 2.0 2 1 0 2 2 2 1 Cyclin, N-terminal domain DSPc PF00782.20 KPA40910.1 - 9.2e-10 38.5 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KPA40910.1 - 0.0004 20.0 0.1 0.00092 18.8 0.1 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KPA40910.1 - 0.023 14.7 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTEN_C2 PF10409.9 KPA40910.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein PTPlike_phytase PF14566.6 KPA40910.1 - 0.15 12.1 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate UPF0121 PF03661.13 KPA40911.1 - 1.3e-32 113.2 6.3 1.6e-32 112.8 6.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Semialdhyde_dh PF01118.24 KPA40912.1 - 7.2e-31 107.1 0.0 1.6e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 KPA40912.1 - 1.7e-08 34.8 0.0 3.4e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 KPA40912.1 - 0.0033 17.5 0.0 0.0081 16.3 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KPA40912.1 - 0.0083 16.4 0.0 0.019 15.3 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPA40912.1 - 0.077 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 KPA40912.1 - 0.13 13.1 0.0 0.3 11.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CRAL_TRIO PF00650.20 KPA40914.1 - 4.4e-25 88.3 0.0 1.6e-24 86.4 0.0 1.8 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KPA40914.1 - 1.1e-10 41.5 0.0 3e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Acid_PPase PF12689.7 KPA40915.1 - 6.1e-65 218.2 0.0 7.3e-65 217.9 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Epimerase PF01370.21 KPA40916.1 - 7.1e-19 68.2 0.0 1.5e-18 67.2 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA40916.1 - 5e-15 55.7 0.0 8.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPA40916.1 - 2e-11 43.4 0.0 3.3e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPA40916.1 - 1.7e-08 33.9 0.0 0.00021 20.6 0.0 2.7 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KPA40916.1 - 2.1e-07 30.3 0.0 3.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Zn_clus PF00172.18 KPA40916.1 - 8.7e-07 29.0 7.8 1.5e-06 28.2 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA40916.1 - 0.00012 21.2 0.3 0.00034 19.7 0.3 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMN_dh PF01070.18 KPA40917.1 - 2e-110 369.1 0.0 2.4e-110 368.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KPA40917.1 - 0.0001 21.6 0.1 0.00016 20.9 0.1 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KPA40917.1 - 0.0036 16.7 0.0 0.29 10.4 0.0 2.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KPA40917.1 - 0.014 14.4 0.2 0.036 13.1 0.2 1.6 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KPA40917.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase SNF2_N PF00176.23 KPA40919.1 - 2.3e-38 131.8 0.8 2.1e-37 128.6 0.0 2.2 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA40919.1 - 8.8e-12 45.4 0.4 2.8e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KPA40919.1 - 4.2e-05 23.3 0.7 0.00011 22.0 0.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KPA40919.1 - 0.00012 21.9 0.0 0.00052 19.8 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 KPA40919.1 - 0.0017 18.7 2.0 0.0038 17.5 2.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KPA40919.1 - 0.0018 18.3 1.4 0.0043 17.0 1.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 KPA40919.1 - 0.0031 17.5 0.0 0.0031 17.5 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KPA40919.1 - 0.011 15.6 0.9 0.027 14.3 0.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPA40919.1 - 0.012 15.5 4.7 0.025 14.5 4.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KPA40919.1 - 0.31 11.0 3.5 0.58 10.1 3.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPA40919.1 - 0.87 9.8 3.9 4.5 7.5 4.3 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KPA40919.1 - 1.8 8.5 5.1 15 5.5 0.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 AT_hook PF02178.19 KPA40919.1 - 2.9 8.0 6.0 8.8 6.6 6.0 1.9 1 0 0 1 1 1 0 AT hook motif PAS_9 PF13426.7 KPA40920.1 - 2.1e-14 53.6 0.0 3.9e-13 49.6 0.0 2.6 2 1 0 2 2 2 1 PAS domain PAS PF00989.25 KPA40920.1 - 2e-07 31.0 0.0 7.7e-05 22.7 0.0 2.9 2 1 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KPA40920.1 - 0.011 16.0 0.0 0.028 14.7 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 KPA40920.1 - 0.012 15.9 0.0 0.42 10.9 0.0 2.7 2 0 0 2 2 2 0 PAS fold RGS PF00615.19 KPA40920.1 - 0.05 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Regulator of G protein signaling domain Ank_2 PF12796.7 KPA40921.1 - 1.6e-37 127.9 0.0 6.8e-08 33.0 0.0 11.2 8 4 3 11 11 11 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA40921.1 - 7.2e-28 96.3 1.1 1.3e-06 28.5 0.0 8.6 9 0 0 9 9 9 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPA40921.1 - 2.5e-24 85.3 0.3 0.00025 21.6 0.0 11.2 9 2 2 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA40921.1 - 4.9e-23 78.7 12.2 0.095 13.3 0.0 15.1 16 1 0 16 16 16 6 Ankyrin repeat Ank PF00023.30 KPA40921.1 - 1.1e-17 63.6 17.6 0.02 15.3 0.0 12.0 13 0 0 13 13 13 6 Ankyrin repeat Acetyltransf_10 PF13673.7 KPA40922.1 - 9.7e-12 44.9 0.0 1e-08 35.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA40922.1 - 2.3e-11 44.0 0.0 6.8e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA40922.1 - 9.1e-11 42.0 0.0 3.1e-09 37.1 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA40922.1 - 9.6e-06 25.7 0.1 0.00015 21.9 0.0 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA40922.1 - 0.00014 21.9 1.9 0.00083 19.4 0.4 2.7 2 1 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KPA40922.1 - 0.0022 17.9 0.0 0.0049 16.8 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein DUF4821 PF16092.5 KPA40922.1 - 0.045 13.4 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) FA_hydroxylase PF04116.13 KPA40923.1 - 1.6e-24 86.7 23.5 4.1e-24 85.4 22.2 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily E1-E2_ATPase PF00122.20 KPA40924.1 - 1.2e-35 122.7 26.6 3.4e-32 111.4 0.2 4.0 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KPA40924.1 - 3.4e-29 101.9 0.6 3.4e-29 101.9 0.6 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KPA40924.1 - 1.2e-19 71.4 0.6 1.1e-15 58.6 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPA40924.1 - 8e-15 54.3 0.0 1.8e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KPA40924.1 - 1.2e-13 50.9 0.0 2.4e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KPA40924.1 - 6.4e-06 26.1 0.9 3.9e-05 23.5 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase p6 PF17548.2 KPA40924.1 - 0.18 11.8 0.3 0.45 10.5 0.3 1.6 1 0 0 1 1 1 0 Histone-like Protein p6 DUF2463 PF09591.10 KPA40924.1 - 0.43 10.4 6.8 0.046 13.6 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) Arb1 PF09692.10 KPA40925.1 - 2.3e-129 432.1 0.0 2.9e-129 431.8 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 CLP1_P PF16575.5 KPA40925.1 - 7.5e-36 123.7 0.0 1.4e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KPA40925.1 - 6.2e-25 87.2 0.0 1.3e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KPA40925.1 - 8.7e-24 84.2 0.1 6.1e-23 81.5 0.1 2.3 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_16 PF13191.6 KPA40925.1 - 0.0003 21.2 0.0 0.00088 19.7 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 KPA40925.1 - 0.0038 17.1 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 KPA40925.1 - 0.0057 16.4 0.0 0.54 10.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 KPA40925.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KPA40925.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.10 KPA40925.1 - 0.073 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPA40925.1 - 0.096 12.8 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA PF00004.29 KPA40925.1 - 0.096 13.1 0.1 0.89 10.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KPA40925.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KPA40925.1 - 0.13 12.6 0.0 0.31 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KPA40925.1 - 0.17 11.6 0.1 0.77 9.5 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_35 PF14516.6 KPA40925.1 - 0.22 10.3 0.0 0.38 9.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain IPK PF03770.16 KPA40926.1 - 1.7e-53 181.4 0.0 2.2e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF2686 PF10887.8 KPA40926.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Pmp3 PF01679.17 KPA40927.1 - 1.3e-19 70.1 11.1 1.8e-19 69.7 11.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator OB_NTP_bind PF07717.16 KPA40928.1 - 3.5e-23 81.7 0.0 7.1e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KPA40928.1 - 1.1e-21 77.2 0.0 1.1e-21 77.2 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KPA40928.1 - 2.7e-13 50.2 0.0 6.9e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KPA40928.1 - 7.1e-12 45.5 0.0 2e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KPA40928.1 - 5.7e-06 26.2 0.4 1.3e-05 25.0 0.4 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KPA40928.1 - 1.2e-05 25.6 0.0 3.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPA40928.1 - 0.00028 20.7 0.1 0.00062 19.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KPA40928.1 - 0.00032 19.8 0.3 0.00096 18.3 0.1 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 KPA40928.1 - 0.0086 16.4 0.2 0.018 15.4 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KPA40928.1 - 0.016 15.3 0.3 0.15 12.1 0.1 2.4 2 1 0 2 2 1 0 AAA domain DUF2075 PF09848.9 KPA40928.1 - 0.022 14.0 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 KPA40928.1 - 0.095 12.3 0.1 0.25 10.9 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KPA40928.1 - 0.11 12.9 0.0 0.41 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 KPA40928.1 - 0.13 12.2 0.1 4 7.4 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding ABC_tran PF00005.27 KPA40928.1 - 0.14 12.6 0.2 0.87 10.1 0.1 2.2 1 1 0 2 2 2 0 ABC transporter DAP3 PF10236.9 KPA40928.1 - 0.15 11.2 0.1 1 8.5 0.1 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 PhoH PF02562.16 KPA40928.1 - 0.16 11.4 0.1 0.36 10.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Spem1 PF15670.5 KPA40928.1 - 1.3 8.5 5.0 2.7 7.5 5.0 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF1509 PF07420.11 KPA40928.1 - 1.7 7.5 13.9 3.1 6.7 13.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Epimerase PF01370.21 KPA40929.1 - 0.004 16.7 0.0 0.014 14.9 0.0 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family HPP PF04982.13 KPA40930.1 - 1e-39 135.5 4.9 1.7e-39 134.8 4.9 1.3 1 0 0 1 1 1 1 HPP family Na_H_Exchanger PF00999.21 KPA40931.1 - 5e-60 203.3 41.7 7.4e-60 202.7 41.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 KPA40931.1 - 0.014 15.9 0.0 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 Universal stress protein family TMEM132D_C PF15706.5 KPA40931.1 - 0.18 11.6 0.1 0.64 9.8 0.1 1.9 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SnoaL PF07366.12 KPA40932.1 - 0.002 18.0 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF373 PF04123.13 KPA40933.1 - 0.12 11.8 1.2 0.13 11.7 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Macoilin PF09726.9 KPA40934.1 - 0.0024 16.5 4.4 0.0027 16.4 4.4 1.1 1 0 0 1 1 1 1 Macoilin family SR-25 PF10500.9 KPA40934.1 - 0.077 12.6 11.6 0.15 11.7 11.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PI3K_1B_p101 PF10486.9 KPA40934.1 - 0.73 7.5 5.8 0.92 7.2 5.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ATG19_autophagy PF12744.7 KPA40934.1 - 3.3 6.8 6.2 5.2 6.2 6.2 1.2 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding VIT PF08487.10 KPA40935.1 - 7.5e-35 119.5 1.8 1.5e-34 118.5 1.8 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KPA40935.1 - 5.9e-28 97.8 0.0 1e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KPA40935.1 - 2.7e-14 52.8 0.1 6.6e-14 51.6 0.1 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KPA40935.1 - 5.4e-12 46.3 0.0 1.4e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KPA40935.1 - 3.1e-08 34.2 0.0 9.6e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Nucleoporin_FG PF13634.6 KPA40935.1 - 0.00015 22.5 28.9 0.00015 22.5 28.9 3.4 2 1 1 3 3 3 1 Nucleoporin FG repeat region Ribosomal_60s PF00428.19 KPA40935.1 - 0.00026 21.5 13.9 0.0061 17.1 3.1 3.0 2 0 0 2 2 2 2 60s Acidic ribosomal protein VWA_CoxE PF05762.14 KPA40935.1 - 0.0023 17.4 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF1655 PF07868.11 KPA40935.1 - 0.095 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1655) Epimerase PF01370.21 KPA40936.1 - 1e-09 38.3 0.2 6.1e-09 35.7 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KPA40936.1 - 2e-05 24.3 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA40936.1 - 0.00037 20.4 0.0 0.00061 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KPA40936.1 - 0.00057 19.1 0.0 0.0064 15.6 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KPA40936.1 - 0.00081 18.5 0.0 0.067 12.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPA40936.1 - 0.0024 17.1 0.1 0.0055 15.9 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KPA40936.1 - 0.0097 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KPA40936.1 - 0.019 15.2 0.1 0.032 14.5 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KPA40936.1 - 0.021 14.2 0.0 0.83 9.0 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KPA40936.1 - 0.047 14.1 0.0 0.092 13.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HLH PF00010.26 KPA40937.1 - 1.7e-17 63.1 0.0 2.8e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nnf1 PF03980.14 KPA40937.1 - 0.0062 16.9 0.1 1.7 9.0 0.0 2.2 2 0 0 2 2 2 2 Nnf1 bZIP_1 PF00170.21 KPA40937.1 - 0.017 15.2 0.5 0.091 12.9 0.3 2.1 2 0 0 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 KPA40937.1 - 0.032 14.5 0.2 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family ZapB PF06005.12 KPA40937.1 - 0.11 12.9 0.3 0.54 10.7 0.2 1.9 2 0 0 2 2 2 0 Cell division protein ZapB DMPK_coil PF08826.10 KPA40937.1 - 0.15 12.2 0.4 0.32 11.1 0.4 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like bZIP_2 PF07716.15 KPA40937.1 - 0.16 12.1 2.1 0.59 10.3 0.5 2.1 2 0 0 2 2 2 0 Basic region leucine zipper DUF2457 PF10446.9 KPA40937.1 - 0.2 10.8 8.9 0.27 10.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CCDC106 PF15794.5 KPA40937.1 - 4.5 6.9 5.8 7.7 6.2 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 WD40 PF00400.32 KPA40939.1 - 2e-23 82.2 9.4 3.4e-09 37.2 0.2 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA40939.1 - 9.7e-09 35.4 0.0 0.08 13.2 0.0 3.6 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA40939.1 - 0.00012 21.1 0.0 0.06 12.3 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PUL PF08324.11 KPA40940.1 - 4.5e-71 239.3 0.4 6.3e-71 238.8 0.4 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KPA40940.1 - 1e-42 144.9 0.5 1.7e-42 144.3 0.5 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KPA40940.1 - 2.3e-29 101.0 10.9 3e-06 27.9 0.1 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA40940.1 - 0.009 16.3 0.5 6.4 7.1 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KPA40940.1 - 0.048 14.2 0.1 0.27 11.8 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain BBS2_Mid PF14783.6 KPA40940.1 - 0.16 12.0 0.0 33 4.6 0.0 3.2 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF1358 PF07096.11 KPA40941.1 - 0.1 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) SRR1 PF07985.12 KPA40942.1 - 1.8e-11 43.9 0.0 2.8e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 SRR1 POPLD PF08170.12 KPA40942.1 - 0.094 13.1 0.1 0.094 13.1 0.1 2.1 3 0 0 3 3 3 0 POPLD (NUC188) domain Cep57_CLD PF14073.6 KPA40943.1 - 0.058 13.4 0.2 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 DUF1465 PF07323.12 KPA40943.1 - 0.076 12.9 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Glyco_hydro_17 PF00332.18 KPA40944.1 - 7.4e-09 35.6 2.7 1.8e-07 31.1 0.9 2.5 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF2315 PF10231.9 KPA40944.1 - 0.18 11.9 1.5 0.23 11.5 0.3 1.7 2 0 0 2 2 2 0 Apoptogenic protein 1 SNARE PF05739.19 KPA40944.1 - 0.27 11.2 1.4 0.5 10.4 1.4 1.4 1 0 0 1 1 1 0 SNARE domain DUF2897 PF11446.8 KPA40944.1 - 0.47 10.4 3.2 1 9.3 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Fungal_trans_2 PF11951.8 KPA40946.1 - 8e-07 28.2 2.3 0.015 14.1 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA40946.1 - 1.2e-06 28.5 2.7 2.5e-06 27.5 2.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex16 PF08610.10 KPA40947.1 - 1.3e-136 455.0 0.1 1.5e-136 454.8 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) zf-met PF12874.7 KPA40948.1 - 0.017 15.5 4.4 0.87 10.1 0.8 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KPA40948.1 - 0.12 13.3 19.2 0.073 13.9 1.6 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger ZZ PF00569.17 KPA40948.1 - 2.5 8.0 7.9 0.57 10.0 3.4 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-C2H2 PF00096.26 KPA40948.1 - 2.7 8.6 17.4 0.13 12.7 1.1 3.3 2 1 1 3 3 3 0 Zinc finger, C2H2 type PP2C_C PF07830.13 KPA40950.1 - 0.12 12.9 0.1 0.99 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain DEAD PF00270.29 KPA40953.1 - 1.7e-43 148.4 0.0 2.8e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA40953.1 - 1.3e-19 70.6 0.0 8.2e-19 68.0 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KPA40953.1 - 5.9e-17 61.7 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KPA40953.1 - 0.0045 17.0 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Collagen_mid PF15984.5 KPA40953.1 - 2.5 7.8 16.4 1.9 8.2 5.5 2.5 1 1 1 2 2 2 0 Bacterial collagen, middle region Cu_bind_like PF02298.17 KPA40954.1 - 2.3e-05 24.3 0.1 4.4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 KPA40954.1 - 6.3e-05 23.3 0.6 0.00015 22.2 0.6 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Lysis_col PF02402.16 KPA40954.1 - 2.3 8.0 4.2 8.9 6.1 3.9 2.2 1 1 0 1 1 1 0 Lysis protein Epimerase PF01370.21 KPA40957.1 - 5.8e-07 29.2 0.0 0.01 15.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPA40957.1 - 4.3e-05 23.5 0.0 0.00013 21.9 0.0 1.8 2 1 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KPA40957.1 - 0.0032 17.9 0.0 0.0063 16.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KPA40957.1 - 0.011 14.8 0.0 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family HSP70 PF00012.20 KPA40958.1 - 1.5e-226 753.3 9.4 1.6e-226 753.2 9.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KPA40958.1 - 5e-17 61.7 0.8 5.7e-16 58.3 0.3 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KPA40958.1 - 0.0011 18.7 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KPA40958.1 - 0.033 13.2 0.9 0.37 9.7 0.1 2.6 2 1 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 KPA40958.1 - 0.88 10.0 11.3 5.7 7.4 0.3 4.2 3 3 0 3 3 3 0 Cell division protein FtsA SNF2_N PF00176.23 KPA40959.1 - 2.8e-12 46.0 0.0 2e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA40959.1 - 3.4e-10 40.2 0.0 8.6e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MA-Mit PF09245.10 KPA40959.1 - 0.033 13.7 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen ResIII PF04851.15 KPA40959.1 - 0.077 13.0 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF913 PF06025.12 KPA40959.1 - 0.17 10.8 0.1 0.26 10.2 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3889 PF13028.6 KPA40960.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) F-box-like PF12937.7 KPA40961.1 - 1.6e-12 47.1 4.8 4.6e-12 45.6 4.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KPA40961.1 - 5e-10 39.0 5.8 6e-10 38.8 3.7 2.2 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KPA40961.1 - 0.00022 21.1 0.1 0.00044 20.1 0.1 1.5 1 0 0 1 1 1 1 F-box WD40 PF00400.32 KPA40961.1 - 0.0046 17.8 0.2 1.6 9.7 0.1 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Elongin_A PF06881.11 KPA40961.1 - 0.012 16.1 0.3 0.012 16.1 0.3 2.4 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PRANC PF09372.10 KPA40961.1 - 0.054 13.8 0.2 0.17 12.3 0.1 1.9 1 1 0 1 1 1 0 PRANC domain SprT-like PF10263.9 KPA40962.1 - 5.6e-16 58.4 0.0 9.3e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 SprT-like family DUF2475 PF10629.9 KPA40962.1 - 0.35 11.1 6.4 0.86 9.9 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) PRIMA1 PF16101.5 KPA40962.1 - 4.2 7.4 5.9 8.4 6.5 5.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TFR_dimer PF04253.15 KPA40963.1 - 4.4e-28 97.8 0.0 7.8e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KPA40963.1 - 4.3e-19 69.0 0.0 7.2e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KPA40963.1 - 1.2e-10 41.2 0.5 4.6e-10 39.4 0.1 2.0 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 KPA40963.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Nicastrin MFS_1 PF07690.16 KPA40964.1 - 1.9e-39 135.6 23.0 3.1e-26 92.1 4.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA40964.1 - 5.3e-08 32.2 4.5 5.3e-08 32.2 4.5 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Pheromone PF08015.11 KPA40964.1 - 0.0056 17.7 1.1 0.014 16.4 0.3 2.0 2 0 0 2 2 2 1 Fungal mating-type pheromone NAD_binding_1 PF00175.21 KPA40965.1 - 4.2e-32 111.0 0.0 8e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KPA40965.1 - 1.6e-24 86.1 0.0 3e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KPA40965.1 - 4.4e-09 36.7 0.0 3.6e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KPA40965.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain SH3_1 PF00018.28 KPA40966.1 - 4e-09 35.9 0.0 6.8e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPA40966.1 - 9.2e-08 31.8 0.1 1.9e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPA40966.1 - 1.5e-05 24.6 0.0 9.6e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain Ssu72 PF04722.13 KPA40967.1 - 1e-85 286.1 0.0 1.2e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Thioredoxin_6 PF13848.6 KPA40967.1 - 0.11 12.4 0.0 1.4 8.8 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like domain AATase PF07247.12 KPA40968.1 - 3.7e-13 48.9 0.0 2.9e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase Tri3 PF07428.11 KPA40968.1 - 0.015 14.2 0.2 0.065 12.1 0.1 1.9 2 0 0 2 2 2 0 15-O-acetyltransferase Tri3 Popeye PF04831.13 KPA40968.1 - 0.14 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Popeye protein conserved region GIT_SHD PF08518.11 KPA40969.1 - 4.9e-23 80.4 5.2 7.5e-13 47.9 1.4 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT NleF_casp_inhib PF16809.5 KPA40969.1 - 0.027 14.4 6.1 0.11 12.4 2.1 2.6 2 0 0 2 2 2 0 NleF caspase inhibitor DpnI_C PF17726.1 KPA40969.1 - 0.087 13.0 0.4 0.26 11.4 0.4 1.8 1 0 0 1 1 1 0 Dam-replacing HTH domain IR1-M PF12185.8 KPA40969.1 - 0.28 11.1 2.1 1.1 9.2 0.1 2.6 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain Baculo_PEP_C PF04513.12 KPA40969.1 - 0.93 9.5 5.0 4.4 7.3 0.4 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ParD_antitoxin PF03693.14 KPA40969.1 - 1.4 9.4 4.8 18 5.8 0.3 2.9 2 0 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Prefoldin PF02996.17 KPA40969.1 - 4.5 7.2 13.9 5.5 6.9 0.7 3.8 3 1 0 3 3 3 0 Prefoldin subunit UDPGT PF00201.18 KPA40970.1 - 2.6e-16 59.5 0.0 4.4e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KPA40970.1 - 9.5e-06 25.7 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF4448 PF14610.6 KPA40971.1 - 8.1e-42 143.1 0.0 1.1e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Rax2 PF12768.7 KPA40971.1 - 0.033 13.6 0.0 0.08 12.4 0.0 1.7 1 1 0 1 1 1 0 Cortical protein marker for cell polarity JmjC PF02373.22 KPA40972.1 - 3.7e-20 72.5 0.0 1.2e-19 70.8 0.0 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase DUF823 PF05689.11 KPA40972.1 - 0.18 11.6 0.1 0.43 10.3 0.0 1.6 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF823) CHASE3 PF05227.13 KPA40973.1 - 0.072 13.0 0.1 0.072 13.0 0.1 2.7 4 0 0 4 4 4 0 CHASE3 domain Ndc1_Nup PF09531.10 KPA40973.1 - 2.7 6.6 12.4 0.66 8.6 6.8 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 KPA40974.1 - 1.7e-21 76.8 0.0 2.5e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KPA40974.1 - 1e-10 42.0 19.4 3.8e-07 30.7 0.0 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.22 KPA40974.1 - 1e-07 31.6 4.9 0.06 13.6 0.1 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KPA40974.1 - 6.8e-05 23.2 2.2 0.17 12.3 0.1 4.5 2 2 0 4 4 4 1 HEAT repeats Pkinase_Tyr PF07714.17 KPA40974.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA40974.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Cnd1 PF12717.7 KPA40974.1 - 0.058 13.4 1.3 7.4 6.6 0.2 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 KPA40974.1 - 0.095 13.0 0.1 4 7.8 0.1 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WH1 PF00568.23 KPA40974.1 - 0.18 11.8 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 WH1 domain HEAT_EZ PF13513.6 KPA40974.1 - 0.41 11.2 3.4 35 5.0 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat LRR_9 PF14580.6 KPA40975.1 - 1.3e-54 184.3 0.5 1.9e-54 183.8 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 KPA40975.1 - 2.1e-10 40.7 14.6 3.4e-06 27.3 2.1 3.3 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPA40975.1 - 4.4e-10 39.2 1.5 1.6e-09 37.4 1.5 2.0 1 0 0 1 1 1 1 Leucine rich repeat DUF4349 PF14257.6 KPA40975.1 - 0.0039 16.7 2.4 0.0068 15.9 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) LRR_6 PF13516.6 KPA40975.1 - 0.075 13.1 2.9 18 5.7 0.2 4.4 5 0 0 5 5 5 0 Leucine Rich repeat DUF3760 PF12586.8 KPA40975.1 - 6.2 7.1 7.4 32 4.8 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3760) CBFD_NFYB_HMF PF00808.23 KPA40976.1 - 9.5e-11 41.8 0.2 1.3e-09 38.2 0.1 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 KPA40976.1 - 0.052 13.8 0.1 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 CENP-W protein Voltage_CLC PF00654.20 KPA40977.1 - 6e-93 311.9 22.4 6e-93 311.9 22.4 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KPA40977.1 - 7.2e-12 45.6 0.1 0.00017 22.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain EamA PF00892.20 KPA40978.1 - 0.00053 20.2 15.9 0.0046 17.1 15.9 1.9 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 KPA40978.1 - 0.058 13.4 3.0 0.079 13.0 3.0 1.3 1 0 0 1 1 1 0 Putative transmembrane family 234 DUF2754 PF10953.8 KPA40978.1 - 0.086 13.1 0.1 1.6 9.0 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2754) TFIIA_gamma_N PF02268.16 KPA40979.1 - 3e-24 84.8 0.2 4.2e-24 84.3 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KPA40979.1 - 1.5e-23 82.7 0.7 2.3e-23 82.1 0.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit ATP-synt_C PF00137.21 KPA40980.1 - 2.2e-26 92.0 28.4 3.8e-15 56.0 11.9 2.4 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 KPA40980.1 - 0.039 13.3 1.8 0.21 10.9 0.1 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3671 PF12420.8 KPA40980.1 - 0.05 13.7 0.3 0.05 13.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function MoCF_biosynth PF00994.24 KPA40981.1 - 1.7e-55 186.7 1.2 6.6e-28 97.2 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KPA40981.1 - 5.9e-41 139.8 3.7 9.6e-41 139.2 3.7 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KPA40981.1 - 2.8e-18 65.9 0.0 1.2e-17 63.8 0.0 2.2 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 KPA40981.1 - 0.58 9.5 6.8 0.9 8.9 6.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RNase_P_Rpp14 PF01900.19 KPA40982.1 - 8.3e-36 122.4 0.0 1e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.17 KPA40983.1 - 2.7e-77 259.8 0.0 3.6e-77 259.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KPA40983.1 - 0.0049 15.9 0.2 0.011 14.7 0.0 1.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 KPA40983.1 - 0.02 14.8 0.0 1.1 9.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPA40983.1 - 0.11 12.9 0.0 0.34 11.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 KPA40983.1 - 0.12 11.6 0.2 0.49 9.6 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KPA40983.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KPA40983.1 - 1.5 9.2 3.6 1.1 9.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain cNMP_binding PF00027.29 KPA40984.1 - 2.3e-28 98.1 1.0 3.3e-15 55.9 0.1 5.5 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KPA40984.1 - 2.6e-15 57.1 4.6 2.7e-14 53.8 4.6 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase Pyridoxal_deC PF00282.19 KPA40986.1 - 9.2e-100 334.0 0.0 1.1e-99 333.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Big_4 PF07532.11 KPA40986.1 - 0.18 11.6 0.2 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) Bul1_N PF04425.12 KPA40987.1 - 6.9e-05 21.8 1.1 0.0018 17.1 0.1 2.4 3 0 0 3 3 3 2 Bul1 N terminus Bul1_C PF04426.12 KPA40987.1 - 0.00026 20.5 0.0 0.0026 17.2 0.0 2.1 2 0 0 2 2 2 1 Bul1 C terminus Arrestin_N PF00339.29 KPA40987.1 - 0.1 12.7 0.1 0.27 11.3 0.1 1.8 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KPA40987.1 - 0.22 12.0 0.9 4.6 7.7 0.2 2.8 3 1 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Zip PF02535.22 KPA40988.1 - 6.2e-57 193.3 3.8 1.3e-56 192.3 3.8 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_17 PF00332.18 KPA40989.1 - 1.4e-07 31.5 0.2 3.5e-07 30.1 0.1 1.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 Shadoo PF14999.6 KPA40989.1 - 3.6 7.7 8.8 0.12 12.5 0.6 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective SUR7 PF06687.12 KPA40990.1 - 5.1e-31 108.0 0.6 6e-31 107.7 0.6 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KPA40990.1 - 3.2e-06 27.2 0.8 3.2e-06 27.2 0.8 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Trp_oprn_chp PF09534.10 KPA40990.1 - 0.0053 16.6 4.2 0.0083 15.9 4.2 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1772 PF08592.11 KPA40990.1 - 0.0077 16.6 5.6 0.0078 16.5 0.5 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1772) DUF4293 PF14126.6 KPA40990.1 - 0.024 14.9 1.5 0.31 11.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Cyt_bd_oxida_I PF01654.17 KPA40990.1 - 0.027 13.1 0.5 0.027 13.1 0.5 2.0 3 0 0 3 3 3 0 Cytochrome bd terminal oxidase subunit I Pox_A14 PF05767.12 KPA40990.1 - 0.038 14.1 6.4 6 7.1 2.1 3.3 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Stevor PF17410.2 KPA40990.1 - 0.1 12.1 1.2 0.18 11.4 1.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Nuf2 PF03800.14 KPA40992.1 - 2e-41 141.3 2.7 2.5e-41 141.0 0.0 2.4 2 1 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 KPA40992.1 - 4.6e-36 123.4 18.5 4.6e-36 123.4 18.5 4.4 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain P22_AR_C PF10548.9 KPA40992.1 - 0.018 15.2 0.6 12 6.1 0.1 3.2 3 0 0 3 3 3 0 P22AR C-terminal domain L27 PF02828.16 KPA40992.1 - 0.11 12.3 1.5 0.45 10.3 0.4 2.5 2 0 0 2 2 2 0 L27 domain VPS11_C PF12451.8 KPA40992.1 - 0.13 12.5 3.8 11 6.3 0.1 4.2 2 2 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Bacillus_HBL PF05791.11 KPA40992.1 - 3.5 7.4 24.1 0.45 10.3 3.2 3.8 3 1 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) McyA_C PF12593.8 KPA40993.1 - 0.068 13.0 0.2 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 Microcystin synthetase C terminal Adaptin_N PF01602.20 KPA40994.1 - 1.9e-102 343.5 0.0 2.4e-102 343.2 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KPA40994.1 - 1.8e-16 60.6 0.2 3.4e-15 56.5 0.0 2.9 2 2 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KPA40994.1 - 1.2e-10 41.7 2.5 6.1e-05 23.3 0.1 5.3 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.22 KPA40994.1 - 1.6e-08 34.1 1.7 0.042 14.1 0.0 5.5 6 0 0 6 6 4 2 HEAT repeat Cohesin_HEAT PF12765.7 KPA40994.1 - 0.00022 21.5 1.2 0.12 12.7 0.0 3.6 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.8 KPA40994.1 - 0.00085 18.9 0.5 0.78 9.3 0.0 3.1 2 1 1 3 3 3 2 CLASP N terminal CRISPR_Cse2 PF09485.10 KPA40994.1 - 0.037 14.6 1.0 10 6.7 0.3 3.1 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) HEAT_EZ PF13513.6 KPA40994.1 - 0.051 14.1 3.2 4.9 7.8 0.0 4.4 5 0 0 5 5 4 0 HEAT-like repeat Cnd3 PF12719.7 KPA40994.1 - 0.23 10.6 0.9 1.4 8.1 0.2 2.6 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain TAP42 PF04177.12 KPA40994.1 - 0.32 10.1 12.6 0.72 8.9 12.6 1.5 1 0 0 1 1 1 0 TAP42-like family SDA1 PF05285.12 KPA40994.1 - 0.94 8.8 21.0 1.9 7.9 21.0 1.4 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 KPA40994.1 - 4.9 6.1 17.6 9 5.2 17.6 1.3 1 0 0 1 1 1 0 Paf1 Myc_N PF01056.18 KPA40994.1 - 5.8 6.7 12.5 12 5.6 12.5 1.5 1 0 0 1 1 1 0 Myc amino-terminal region DUF2722 PF10846.8 KPA40994.1 - 6.5 5.6 9.0 10 4.9 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pox_Ag35 PF03286.14 KPA40994.1 - 6.8 6.4 13.7 16 5.2 13.7 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RTA1 PF04479.13 KPA40995.1 - 3.4e-69 232.6 2.0 4.9e-69 232.1 2.0 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.6 KPA40995.1 - 1.2 8.7 9.0 2.9 7.5 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) NAD_binding_2 PF03446.15 KPA40996.1 - 2.4e-39 135.1 0.1 3.6e-39 134.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KPA40996.1 - 3.2e-29 101.6 0.1 6e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KPA40996.1 - 8.4e-07 29.5 0.1 2.5e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KPA40996.1 - 0.00017 20.7 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Ldh_1_N PF00056.23 KPA40996.1 - 0.00036 20.6 0.1 0.001 19.2 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KPA40996.1 - 0.00086 20.1 0.0 0.0027 18.5 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 KPA40996.1 - 0.007 16.6 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 KPA40996.1 - 0.011 15.3 0.1 0.036 13.7 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KPA40996.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribosom_S30AE_C PF16321.5 KPA40996.1 - 0.2 11.3 0.4 0.46 10.2 0.4 1.6 1 1 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus KilA-N PF04383.13 KPA40997.1 - 0.047 13.5 0.3 0.97 9.3 0.0 2.5 2 1 1 3 3 3 0 KilA-N domain DUF4366 PF14283.6 KPA40997.1 - 0.19 11.7 3.4 0.18 11.9 1.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) CDC45 PF02724.14 KPA40997.1 - 1.5 7.1 7.7 2.3 6.4 7.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Rho_GDI PF02115.17 KPA40998.1 - 1.6e-66 223.8 0.2 1.7e-66 223.7 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.15 KPA40998.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.6 1 1 0 1 1 1 0 ML domain Ribosomal_S16 PF00886.19 KPA40998.1 - 0.18 11.9 0.1 0.52 10.4 0.1 1.8 1 1 0 1 1 1 0 Ribosomal protein S16 Metallophos PF00149.28 KPA40999.1 - 6.3e-36 124.8 0.3 8.3e-36 124.4 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPA40999.1 - 0.045 14.0 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 KPA40999.1 - 0.12 12.8 0.2 0.32 11.5 0.2 1.7 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain zf-CCHC PF00098.23 KPA41000.1 - 4.5e-05 23.3 1.7 9.7e-05 22.3 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KPA41000.1 - 0.047 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle His_Phos_2 PF00328.22 KPA41001.1 - 6.3e-49 167.3 0.0 7.5e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ammonium_transp PF00909.21 KPA41002.1 - 1.2e-113 379.9 32.5 1.3e-113 379.7 32.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Glucan_synthase PF02364.15 KPA41002.1 - 0.26 9.4 3.3 0.068 11.3 0.2 1.4 2 0 0 2 2 2 0 1,3-beta-glucan synthase component CRT10 PF08728.10 KPA41003.1 - 3e-16 58.8 0.0 4.6e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 CRT10 Cellulase PF00150.18 KPA41004.1 - 1.1e-35 123.4 0.6 1.4e-35 123.1 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) 7tm_2 PF00002.24 KPA41005.1 - 2.7e-06 26.9 15.5 2.7e-06 26.9 15.5 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) DUF4005 PF13178.6 KPA41005.1 - 4.7 7.9 6.0 8.7 7.1 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4005) FolB PF02152.18 KPA41006.1 - 1.6e-22 80.1 0.1 1.2e-18 67.6 0.1 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase DUF3605 PF12239.8 KPA41007.1 - 4.8e-55 186.1 0.1 5.9e-55 185.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) UDPGP PF01704.18 KPA41008.1 - 5.1e-193 641.3 0.0 5.9e-193 641.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Smoothelin PF12510.8 KPA41008.1 - 0.21 11.7 0.1 6.6 6.9 0.0 3.2 4 0 0 4 4 4 0 Smoothelin cytoskeleton protein GPI-anchored PF10342.9 KPA41009.1 - 2.1e-11 44.4 0.4 2.1e-11 44.4 0.4 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4854 PF16146.5 KPA41009.1 - 0.049 14.0 0.2 0.081 13.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) Gmx_para_CXXCG PF09535.10 KPA41010.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) DUF3336 PF11815.8 KPA41011.1 - 1.1e-26 93.2 0.0 2.2e-25 89.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KPA41011.1 - 1.4e-12 48.2 0.1 3.1e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Sm_multidrug_ex PF06695.11 KPA41011.1 - 0.068 13.8 0.4 0.17 12.6 0.4 1.6 1 0 0 1 1 1 0 Putative small multi-drug export protein Leo1 PF04004.13 KPA41012.1 - 9e-37 126.5 1.0 1.5e-36 125.7 0.1 1.9 2 0 0 2 2 2 1 Leo1-like protein Spore_coat_CotO PF14153.6 KPA41012.1 - 5.2 7.0 14.8 0.41 10.5 2.1 3.1 3 0 0 3 3 3 0 Spore coat protein CotO Mob1_phocein PF03637.17 KPA41013.1 - 1.5e-42 145.5 0.1 3.1e-42 144.5 0.1 1.5 1 1 0 1 1 1 1 Mob1/phocein family DUF3237 PF11578.8 KPA41014.1 - 2.2e-26 92.5 0.0 2.5e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) bZIP_1 PF00170.21 KPA41015.1 - 2.2e-08 34.1 17.7 4.9e-08 33.0 14.6 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KPA41015.1 - 2.2e-07 31.3 10.7 6e-07 29.9 10.7 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KPA41015.1 - 8.2e-05 22.6 14.4 0.00037 20.5 14.4 2.2 1 1 0 1 1 1 1 Basic region leucine zipper PI_PP_I PF18363.1 KPA41015.1 - 0.15 12.3 1.1 0.37 11.0 1.1 1.7 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain FapA PF03961.13 KPA41015.1 - 1.6 7.2 10.4 2.4 6.7 10.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 KPA41015.1 - 1.8 7.7 4.5 2.6 7.2 4.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 KPA41015.1 - 2.5 8.1 17.2 4.8 7.2 17.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sel1 PF08238.12 KPA41016.1 - 1.8e-10 41.1 9.1 0.003 18.2 0.7 4.0 4 0 0 4 4 4 3 Sel1 repeat zf-CCCH PF00642.24 KPA41018.1 - 1.8e-07 30.9 29.0 6.7e-06 25.9 0.3 5.3 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KPA41018.1 - 8.3e-06 25.5 1.8 0.00024 20.8 0.4 4.7 5 0 0 5 5 5 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KPA41018.1 - 0.00025 21.0 1.3 0.00025 21.0 1.3 5.8 5 1 0 5 5 5 2 Zinc finger domain Torus PF16131.5 KPA41018.1 - 0.0024 18.5 5.8 0.021 15.5 0.3 5.0 2 1 3 5 5 5 2 Torus domain zf-CCCH_3 PF15663.5 KPA41018.1 - 0.95 9.7 17.3 0.6 10.4 5.8 3.6 1 1 2 3 3 3 0 Zinc-finger containing family THOC7 PF05615.13 KPA41019.1 - 5.1e-42 143.3 8.3 5.1e-42 143.3 8.3 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 FUSC PF04632.12 KPA41019.1 - 0.91 8.0 8.3 1.2 7.6 8.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMPIT PF07851.13 KPA41019.1 - 1.1 8.4 5.5 7.5 5.7 0.6 2.2 2 0 0 2 2 2 0 TMPIT-like protein OmpH PF03938.14 KPA41019.1 - 1.5 9.2 7.6 3.2 8.1 7.6 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TBCA PF02970.16 KPA41020.1 - 3.6e-24 84.9 4.9 3.6e-24 84.9 4.9 1.6 1 1 1 2 2 2 1 Tubulin binding cofactor A DUF1910 PF08928.10 KPA41020.1 - 0.038 14.0 0.3 0.038 14.0 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Bap31_Bap29_C PF18035.1 KPA41020.1 - 0.062 13.3 1.6 0.062 13.3 1.6 2.6 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Csm1_N PF18504.1 KPA41020.1 - 0.6 10.5 12.0 0.23 11.8 2.2 2.6 2 2 0 2 2 2 0 Csm1 N-terminal domain Rad21_Rec8_N PF04825.13 KPA41021.1 - 1.3e-37 128.4 0.1 2.5e-37 127.4 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KPA41021.1 - 4.2e-08 32.3 0.0 8.4e-08 31.4 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein E1-E2_ATPase PF00122.20 KPA41022.1 - 9.3e-45 152.4 0.1 9.3e-45 152.4 0.1 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KPA41022.1 - 2.3e-43 148.0 0.4 5.2e-43 146.9 0.4 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KPA41022.1 - 5.2e-21 75.9 1.8 2.9e-20 73.4 0.6 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPA41022.1 - 1.6e-18 66.2 0.0 2.9e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KPA41022.1 - 1.4e-11 44.3 0.0 2.8e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KPA41022.1 - 0.00014 21.7 0.9 0.00044 20.1 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 KPA41026.1 - 4.6e-12 45.5 0.0 9.8e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41026.1 - 3.4e-06 27.1 7.7 5.9e-06 26.3 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SlyX PF04102.12 KPA41026.1 - 0.037 14.6 3.4 0.13 12.9 0.1 3.2 4 0 0 4 4 4 0 SlyX NPV_P10 PF05531.12 KPA41026.1 - 0.06 13.8 0.2 0.2 12.2 0.2 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KPA41026.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AA_permease_2 PF13520.6 KPA41027.1 - 2.1e-62 211.4 47.4 2.5e-62 211.1 47.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA41027.1 - 5e-23 81.4 43.5 6e-23 81.2 43.5 1.0 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.20 KPA41028.1 - 1.3e-163 544.7 0.0 1.6e-163 544.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KPA41028.1 - 8.9e-08 32.3 0.0 1.9e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KPA41028.1 - 6.2e-05 23.3 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain adh_short_C2 PF13561.6 KPA41029.1 - 4.7e-46 157.2 3.3 5.7e-46 157.0 3.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA41029.1 - 2.5e-43 147.8 1.6 3.2e-43 147.5 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA41029.1 - 1.3e-16 61.0 2.8 1.8e-16 60.6 2.8 1.1 1 0 0 1 1 1 1 KR domain Mur_ligase PF01225.25 KPA41029.1 - 0.073 13.4 0.0 0.39 11.1 0.0 2.3 2 0 0 2 2 2 0 Mur ligase family, catalytic domain Fungal_trans PF04082.18 KPA41030.1 - 1.1e-20 73.9 0.0 1.8e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41030.1 - 6.2e-09 35.8 10.8 1.1e-08 35.0 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SLAC1 PF03595.17 KPA41031.1 - 9.5e-81 271.6 44.5 1.1e-80 271.4 44.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Abhydrolase_6 PF12697.7 KPA41032.1 - 1.3e-06 29.1 0.0 2.3e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA41032.1 - 0.00057 19.6 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Aldedh PF00171.22 KPA41033.1 - 2.1e-183 610.1 0.2 2.4e-183 609.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPA41033.1 - 0.0035 16.8 0.0 0.4 10.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) AA_permease_2 PF13520.6 KPA41034.1 - 3.9e-52 177.5 51.4 4.9e-52 177.2 51.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA41034.1 - 3.7e-16 58.8 42.5 5.9e-16 58.1 42.5 1.2 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.20 KPA41035.1 - 1.6e-157 524.6 0.1 2.1e-157 524.2 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KPA41035.1 - 4.6e-19 68.7 0.0 1.2e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KPA41035.1 - 2.3e-14 53.4 0.0 4.3e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Pyr_redox_3 PF13738.6 KPA41036.1 - 1.4e-10 41.0 1.2 8e-08 31.9 0.6 3.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPA41036.1 - 2.6e-09 36.1 0.6 1.6e-08 33.4 0.1 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPA41036.1 - 4.7e-07 29.3 1.0 3.6e-05 23.1 0.0 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPA41036.1 - 5.1e-07 29.2 0.5 0.0088 15.3 0.1 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA41036.1 - 8.3e-07 28.9 0.1 5e-06 26.3 0.1 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA41036.1 - 2.5e-05 24.4 0.0 6.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPA41036.1 - 0.0011 19.0 0.5 0.4 10.7 0.0 2.9 4 0 0 4 4 4 2 FAD-NAD(P)-binding Thi4 PF01946.17 KPA41036.1 - 0.023 14.0 0.2 0.19 11.0 0.1 2.1 2 0 0 2 2 2 0 Thi4 family adh_short PF00106.25 KPA41037.1 - 2.3e-36 125.1 0.0 3.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA41037.1 - 7.4e-27 94.4 0.0 1.2e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA41037.1 - 0.023 14.6 0.0 0.055 13.4 0.0 1.6 2 0 0 2 2 2 0 KR domain GCN5L1 PF06320.13 KPA41037.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Fungal_trans_2 PF11951.8 KPA41038.1 - 1.5e-08 33.9 0.0 2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41038.1 - 1.4e-07 31.5 10.2 2.5e-07 30.7 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.17 KPA41038.1 - 0.093 12.9 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 KPA41040.1 - 7.3e-58 195.9 0.2 1.1e-57 195.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA41040.1 - 1e-48 165.4 0.5 1.4e-48 165.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA41040.1 - 0.0001 22.2 1.5 0.001 19.0 1.5 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA41040.1 - 0.007 15.8 0.1 0.9 8.9 0.1 2.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GAS PF13851.6 KPA41041.1 - 4.9e-06 26.0 23.4 1.1e-05 24.9 12.0 7.6 3 2 4 7 7 7 5 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 KPA41041.1 - 1.9e-05 23.8 14.9 1.9e-05 23.8 14.9 4.9 2 1 2 4 4 4 2 Calcium binding and coiled-coil domain (CALCOCO1) like APG6_N PF17675.1 KPA41041.1 - 4.7e-05 23.9 141.3 0.0064 17.0 17.8 7.9 2 2 4 7 7 7 6 Apg6 coiled-coil region SHE3 PF17078.5 KPA41041.1 - 0.00013 21.8 11.0 0.00013 21.8 11.0 7.4 2 2 4 6 6 6 1 SWI5-dependent HO expression protein 3 DUF2968 PF11180.8 KPA41041.1 - 0.003 17.2 9.9 0.003 17.2 9.9 9.1 3 2 5 9 9 9 3 Protein of unknown function (DUF2968) DUF4164 PF13747.6 KPA41041.1 - 0.0068 16.7 4.6 0.0068 16.7 4.6 9.4 3 3 7 10 10 10 1 Domain of unknown function (DUF4164) CENP-F_leu_zip PF10473.9 KPA41041.1 - 0.0099 15.9 18.2 0.0099 15.9 18.2 8.9 2 2 7 9 9 9 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Shugoshin_N PF07558.11 KPA41041.1 - 1.3 8.9 10.5 0.85 9.5 0.0 5.1 6 0 0 6 6 6 0 Shugoshin N-terminal coiled-coil region Spc7 PF08317.11 KPA41041.1 - 6.4 5.6 129.3 0.04 12.8 22.4 5.9 3 2 2 5 5 5 0 Spc7 kinetochore protein AA_permease_2 PF13520.6 KPA41042.1 - 3.8e-44 151.2 51.6 4.4e-44 151.0 51.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA41042.1 - 4.5e-23 81.6 45.4 6.2e-23 81.1 45.4 1.1 1 0 0 1 1 1 1 Amino acid permease CTV_P6 PF06706.11 KPA41042.1 - 0.0013 18.4 1.1 0.66 9.7 0.1 3.3 2 0 0 2 2 2 2 Citrus tristeza virus 6-kDa protein SBP_bac_6 PF13343.6 KPA41043.1 - 5.2e-13 49.0 0.3 8.9e-13 48.2 0.3 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KPA41043.1 - 3.5e-11 43.4 2.0 7.4e-09 35.8 2.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KPA41043.1 - 6e-08 33.0 3.2 3.8e-07 30.4 3.2 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KPA41043.1 - 4.6e-06 26.6 0.1 7.6e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Glyco_hydro_16 PF00722.21 KPA41044.1 - 9e-10 38.3 0.5 5e-09 35.9 0.0 2.3 1 1 2 3 3 3 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KPA41044.1 - 0.00089 17.8 0.1 0.0015 17.0 0.1 1.3 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) CAP_N PF01213.19 KPA41044.1 - 0.27 10.7 5.0 0.36 10.3 5.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ATG_C PF09333.11 KPA41045.1 - 0.0019 18.5 0.1 0.0027 18.0 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain PLAC8 PF04749.17 KPA41046.1 - 7.2e-22 78.3 13.2 8.9e-22 78.0 13.2 1.1 1 0 0 1 1 1 1 PLAC8 family Fumble PF03630.14 KPA41047.1 - 2.6e-60 204.4 0.0 2.9e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Fumble Gifsy-2 PF13856.6 KPA41047.1 - 0.16 12.4 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage DUF2116 PF09889.9 KPA41048.1 - 0.65 10.0 16.5 0.044 13.8 2.2 3.3 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ank_4 PF13637.6 KPA41049.1 - 0.0092 16.6 0.1 39 5.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA41049.1 - 0.013 16.0 0.2 5.3 7.7 0.2 2.8 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) ATP_transf PF09830.9 KPA41050.1 - 3.5e-17 62.3 0.2 9.3e-17 60.9 0.2 1.8 1 0 0 1 1 1 1 ATP adenylyltransferase Abhydrolase_6 PF12697.7 KPA41051.1 - 7.3e-13 49.6 0.0 6.8e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA41051.1 - 6e-07 29.0 0.1 0.00035 19.9 0.0 3.0 3 1 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA41051.1 - 0.0013 18.4 0.0 0.0074 15.9 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold FAD_binding_4 PF01565.23 KPA41052.1 - 3.7e-17 62.4 0.6 6.8e-17 61.5 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KPA41052.1 - 2e-06 27.9 2.1 3.7e-05 23.7 0.2 2.6 2 1 0 2 2 2 1 D-arabinono-1,4-lactone oxidase VWA PF00092.28 KPA41052.1 - 0.087 13.1 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain LysM PF01476.20 KPA41053.1 - 0.0058 16.7 0.0 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 LysM domain BTB PF00651.31 KPA41054.1 - 9.2e-08 32.3 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 KPA41055.1 - 2.8e-12 46.2 48.5 4.8e-12 45.5 45.6 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily FUN14 PF04930.15 KPA41055.1 - 0.046 14.1 7.2 0.16 12.4 7.2 1.9 1 0 0 1 1 1 0 FUN14 family CN_hydrolase PF00795.22 KPA41056.1 - 9.5e-30 103.8 0.0 5.6e-29 101.3 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase WLM PF08325.10 KPA41057.1 - 7.3e-50 169.7 0.0 1.2e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 KPA41057.1 - 0.00017 21.7 0.9 0.00017 21.7 0.9 2.1 3 0 0 3 3 3 1 Protein of unknown function DUF45 Reprolysin_5 PF13688.6 KPA41057.1 - 0.043 13.9 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 SprT-like PF10263.9 KPA41057.1 - 0.06 13.2 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 SprT-like family Coiled PF05710.12 KPA41060.1 - 0.11 13.4 5.0 0.15 12.9 5.0 1.3 1 0 0 1 1 1 0 Coiled coil DUF3659 PF12396.8 KPA41061.1 - 9.5e-20 70.3 7.7 4.5e-13 48.9 1.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3659) EFTUD2 PF16004.5 KPA41061.1 - 7 7.3 7.8 2.7 8.6 0.5 2.7 3 0 0 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF3659 PF12396.8 KPA41062.1 - 2.5e-178 578.2 118.9 6e-22 77.3 3.0 11.3 12 0 0 12 12 12 10 Protein of unknown function (DUF3659) Clavanin PF05452.11 KPA41062.1 - 4.4e-07 30.0 18.1 0.41 10.9 0.2 7.9 8 0 0 8 8 8 3 Clavanin RPW8 PF05659.11 KPA41062.1 - 0.0097 15.6 0.4 0.021 14.5 0.4 1.5 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 GCV_T_C PF08669.11 KPA41062.1 - 0.03 14.2 5.6 49 3.9 0.0 6.6 7 0 0 7 7 7 0 Glycine cleavage T-protein C-terminal barrel domain BNR PF02012.20 KPA41062.1 - 0.66 10.2 7.2 1.9 8.8 0.1 3.7 3 0 0 3 3 3 0 BNR/Asp-box repeat His_Phos_1 PF00300.22 KPA41063.1 - 2.1e-30 105.8 0.5 4.5e-29 101.5 0.5 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ERCC4 PF02732.15 KPA41064.1 - 2.9e-25 89.3 0.1 5.5e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain Kinesin PF00225.23 KPA41065.1 - 1.9e-93 313.0 1.4 6.1e-93 311.4 0.0 2.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KPA41065.1 - 4e-20 72.3 0.0 6e-17 62.0 0.0 3.1 2 0 0 2 2 2 2 Microtubule binding DNA_binding_1 PF01035.20 KPA41066.1 - 2.7e-26 91.5 0.1 3.2e-26 91.2 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF4224 PF13986.6 KPA41066.1 - 0.075 12.9 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Glyco_hydro_1 PF00232.18 KPA41067.1 - 1.7e-77 260.8 1.2 3.7e-75 253.1 1.2 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 ADH_N PF08240.12 KPA41068.1 - 9.6e-25 86.6 3.9 1.6e-24 85.8 3.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA41068.1 - 4e-20 72.1 0.0 6.8e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA41068.1 - 2e-10 41.8 0.0 3.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPA41068.1 - 0.0026 17.1 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KPA41068.1 - 0.0033 16.7 0.1 0.0055 16.0 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_19 PF04672.12 KPA41071.1 - 0.043 13.3 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl methyltransferase PMP1_2 PF08114.11 KPA41071.1 - 0.29 10.9 0.9 0.63 9.8 0.9 1.6 1 0 0 1 1 1 0 ATPase proteolipid family Asp PF00026.23 KPA41072.1 - 1.2e-05 25.0 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic aspartyl protease AA_permease PF00324.21 KPA41073.1 - 1e-127 426.7 34.9 1.3e-127 426.4 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA41073.1 - 1.2e-42 146.3 35.2 1.5e-42 145.9 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3328 PF11807.8 KPA41075.1 - 4.4e-50 170.5 0.3 5.8e-50 170.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NMT1 PF09084.11 KPA41076.1 - 2.3e-78 263.1 0.0 3e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KPA41076.1 - 2.3e-05 24.2 0.0 0.29 10.8 0.0 3.8 3 1 1 4 4 4 2 NMT1-like family Phosphonate-bd PF12974.7 KPA41076.1 - 0.046 13.3 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.7 KPA41076.1 - 0.17 11.0 0.1 2.8 7.0 0.0 2.4 2 1 0 3 3 3 0 PBP superfamily domain Y_phosphatase2 PF03162.13 KPA41077.1 - 4e-43 146.9 0.0 6.8e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KPA41077.1 - 2.8e-10 40.6 0.8 1.9e-09 37.8 0.1 2.4 2 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 KPA41077.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KPA41077.1 - 0.029 13.9 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Aim19 PF10315.9 KPA41078.1 - 0.00014 22.2 2.4 0.0012 19.2 0.1 2.1 1 1 1 2 2 2 2 Altered inheritance of mitochondria protein 19 Zn_clus PF00172.18 KPA41079.1 - 2e-07 31.0 13.1 3.2e-07 30.3 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pho88 PF10032.9 KPA41081.1 - 1.6e-81 272.0 0.2 1.8e-81 271.8 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) XPA_C PF05181.12 KPA41082.1 - 1.9e-26 91.8 1.6 3.9e-26 90.7 1.6 1.6 1 0 0 1 1 1 1 XPA protein C-terminus FRG1 PF06229.12 KPA41082.1 - 0.0058 16.4 1.5 0.015 15.0 1.5 1.7 1 0 0 1 1 1 1 FRG1-like domain zf-C3HC4_3 PF13920.6 KPA41082.1 - 0.24 11.3 8.0 0.084 12.7 4.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) XPA_N PF01286.18 KPA41082.1 - 1.4 9.0 15.0 0.22 11.6 9.6 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Striatin PF08232.12 KPA41083.1 - 4.8e-40 137.7 5.1 4.8e-40 137.7 5.1 2.5 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 KPA41083.1 - 5.4e-25 87.2 16.6 0.00022 21.9 0.1 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA41083.1 - 2.2e-05 24.6 0.1 1.4 9.3 0.0 4.8 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPA41083.1 - 0.017 15.0 0.0 0.076 12.9 0.0 2.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF5018 PF16410.5 KPA41083.1 - 0.076 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) Ge1_WD40 PF16529.5 KPA41083.1 - 0.096 11.6 0.0 1.1 8.2 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3435 PF11917.8 KPA41084.1 - 3.5e-10 39.4 0.4 1.9e-09 37.0 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) zf-Di19 PF05605.12 KPA41084.1 - 2.4e-05 24.5 0.4 2.4e-05 24.5 0.4 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KPA41084.1 - 0.0051 17.2 0.6 0.0051 17.2 0.6 4.4 5 0 0 5 5 5 2 Zinc-finger double domain DUF4451 PF14616.6 KPA41084.1 - 0.2 11.9 3.4 2.4 8.4 0.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-C2H2_4 PF13894.6 KPA41084.1 - 5.2 8.2 18.0 3.8 8.6 1.1 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger DUF4887 PF16228.5 KPA41085.1 - 9.6 6.3 10.4 11 6.2 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) MCM PF00493.23 KPA41086.1 - 2.7e-103 343.9 0.9 4.7e-103 343.1 0.4 1.6 1 1 1 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KPA41086.1 - 1.2e-39 135.0 0.7 6.4e-39 132.7 0.5 2.2 2 0 0 2 2 2 1 MCM OB domain MCM6_C PF18263.1 KPA41086.1 - 3.4e-34 117.3 0.2 8.4e-34 116.1 0.2 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 KPA41086.1 - 1.3e-24 86.7 0.3 6.6e-24 84.5 0.3 2.3 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 KPA41086.1 - 3.1e-24 85.2 0.5 3.1e-24 85.2 0.5 2.8 3 1 0 3 3 3 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KPA41086.1 - 1.2e-07 31.3 0.0 4.5e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KPA41086.1 - 0.00091 19.1 0.5 0.0033 17.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KPA41086.1 - 0.0015 18.2 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KPA41086.1 - 0.1 12.6 0.0 0.31 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) C_Hendra PF16821.5 KPA41086.1 - 0.13 12.1 0.0 0.49 10.3 0.0 2.0 1 0 0 1 1 1 0 C protein from hendra and measles viruses GIDA_assoc PF13932.6 KPA41086.1 - 0.23 11.6 2.9 0.65 10.1 2.9 1.8 1 0 0 1 1 1 0 GidA associated domain Thi4 PF01946.17 KPA41087.1 - 5.1e-121 402.3 0.1 6.1e-121 402.0 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KPA41087.1 - 3.2e-06 27.0 1.2 8.5e-06 25.6 1.1 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA41087.1 - 0.0001 22.4 0.8 0.00028 21.1 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPA41087.1 - 0.00026 20.2 0.4 0.00057 19.0 0.3 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KPA41087.1 - 0.00057 19.2 0.0 0.00076 18.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA41087.1 - 0.00082 19.4 0.2 0.0033 17.4 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KPA41087.1 - 0.0018 17.4 1.4 0.025 13.7 0.4 2.5 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 KPA41087.1 - 0.0059 16.0 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA41087.1 - 0.039 12.7 0.4 0.059 12.1 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KPA41087.1 - 0.041 13.1 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA41087.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Aminotran_5 PF00266.19 KPA41089.1 - 1.6e-22 80.0 0.0 2.4e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SIR2 PF02146.17 KPA41090.1 - 1.6e-32 112.9 0.0 4.2e-10 39.8 0.0 3.2 2 1 0 3 3 3 3 Sir2 family Pro-kuma_activ PF09286.11 KPA41091.1 - 3e-25 89.2 0.0 5.6e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KPA41091.1 - 3.9e-07 29.6 0.2 6.9e-07 28.8 0.2 1.4 1 0 0 1 1 1 1 Subtilase family PALP PF00291.25 KPA41092.1 - 6.7e-18 65.1 0.0 2e-17 63.5 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 KPA41092.1 - 7.2e-07 29.7 0.0 2.2e-05 25.0 0.0 2.6 1 1 0 1 1 1 1 Rhodanese-like domain Whi5 PF08528.11 KPA41094.1 - 9.6e-12 44.3 0.0 1.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Whi5 like zf-C2HC5 PF06221.13 KPA41095.1 - 1.3e-21 76.3 5.4 2e-21 75.7 5.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.6 KPA41095.1 - 0.2 11.1 2.2 8.7 5.9 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Ldh_1_C PF02866.18 KPA41096.1 - 5.4e-46 156.6 0.0 1.2e-45 155.5 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KPA41096.1 - 4.2e-42 143.6 0.5 1.1e-41 142.3 0.1 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KPA41096.1 - 2.6e-05 23.4 0.0 3.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family E1-E2_ATPase PF00122.20 KPA41097.1 - 1.6e-16 60.4 0.0 3.5e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KPA41097.1 - 2.7e-15 57.2 5.2 2.2e-09 37.9 4.5 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KPA41097.1 - 0.0021 17.8 0.0 0.058 13.1 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KPA41097.1 - 0.027 14.5 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Cation transport ATPase (P-type) TBCC_N PF16752.5 KPA41097.1 - 4.3 7.8 7.3 9.6 6.7 7.3 1.6 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Abhydrolase_3 PF07859.13 KPA41098.1 - 4.4e-53 180.3 0.0 5.4e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPA41098.1 - 8.1e-07 28.3 0.1 3e-06 26.4 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KPA41098.1 - 0.0003 20.3 0.0 0.0017 17.9 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KPA41098.1 - 0.0009 18.2 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase AXE1 PF05448.12 KPA41098.1 - 0.014 14.1 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KPA41099.1 - 6e-21 75.2 0.2 2.7e-20 73.1 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA41099.1 - 4.2e-16 60.2 0.4 5.1e-16 59.9 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA41099.1 - 2.8e-08 33.3 0.0 1.7e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KPA41099.1 - 0.047 12.4 0.0 0.09 11.5 0.0 1.4 1 1 0 1 1 1 0 Ndr family Lipase_2 PF01674.18 KPA41099.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 2) p450 PF00067.22 KPA41100.1 - 6.8e-49 166.9 0.0 1.4e-48 165.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 IL32 PF15225.6 KPA41100.1 - 0.065 13.6 0.4 0.21 11.9 0.1 2.0 2 0 0 2 2 2 0 Interleukin 32 MFS_1 PF07690.16 KPA41101.1 - 4.5e-52 177.1 21.3 4.5e-52 177.1 21.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA41101.1 - 6.2e-10 38.5 9.2 6.2e-10 38.5 9.2 2.7 2 2 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KPA41101.1 - 4.2e-09 35.4 6.3 7.6e-09 34.5 6.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KPA41101.1 - 0.0038 16.1 0.2 0.0038 16.1 0.2 2.0 2 0 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 KPA41101.1 - 0.0051 15.3 3.3 0.01 14.3 3.3 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_5 PF05631.14 KPA41101.1 - 0.0062 15.5 1.9 0.0062 15.5 1.9 2.0 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Metallophos_2 PF12850.7 KPA41101.1 - 0.036 14.3 0.3 2.4 8.3 0.3 2.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CPP1-like PF11833.8 KPA41101.1 - 0.53 9.9 7.9 0.91 9.2 5.1 2.4 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like OATP PF03137.20 KPA41101.1 - 1.2 7.3 7.4 0.2 9.9 1.3 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family D-ser_dehydrat PF14031.6 KPA41102.1 - 2.2e-25 89.1 0.2 6.6e-25 87.6 0.2 1.9 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KPA41102.1 - 1.2e-15 57.7 0.1 1.8e-14 53.9 0.0 2.5 3 0 0 3 3 3 1 Alanine racemase, N-terminal domain DUF5353 PF17304.2 KPA41102.1 - 9.3e-10 38.1 4.9 1.9e-09 37.1 4.9 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5353) CHCH PF06747.13 KPA41103.1 - 0.00042 20.4 6.8 0.00072 19.6 6.8 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KPA41103.1 - 0.22 11.9 1.9 0.71 10.3 1.9 1.9 1 0 0 1 1 1 0 GCK domain TPK_catalytic PF04263.16 KPA41104.1 - 8.6e-30 103.3 0.0 1.3e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KPA41104.1 - 3.6e-25 87.5 0.1 5.2e-25 86.9 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain ANAPC4 PF12896.7 KPA41104.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 AAT PF03417.16 KPA41105.1 - 5.8e-28 98.1 0.0 7.5e-27 94.5 0.0 2.5 3 0 0 3 3 3 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase V-SNARE_C PF12352.8 KPA41105.1 - 8.2e-13 48.4 1.6 1.2e-12 47.9 0.1 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KPA41105.1 - 3.6e-05 23.6 0.8 0.00065 19.6 0.0 2.5 2 0 0 2 2 2 1 Sec20 VBS PF08913.10 KPA41105.1 - 0.022 15.2 0.1 0.046 14.2 0.1 1.5 1 0 0 1 1 1 0 Vinculin Binding Site TPR_MLP1_2 PF07926.12 KPA41105.1 - 0.037 14.1 9.5 0.092 12.8 6.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein BAR_3 PF16746.5 KPA41105.1 - 0.13 12.0 1.2 8.3 6.0 1.0 2.3 2 0 0 2 2 2 0 BAR domain of APPL family TMP_2 PF06791.13 KPA41105.1 - 0.19 11.4 0.8 0.35 10.5 0.1 1.9 2 0 0 2 2 2 0 Prophage tail length tape measure protein DUF4407 PF14362.6 KPA41105.1 - 7.5 5.8 6.8 19 4.5 6.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Beta-lactamase PF00144.24 KPA41106.1 - 7.4e-31 107.6 0.8 2e-30 106.2 0.8 1.6 1 1 0 1 1 1 1 Beta-lactamase DUF1126 PF06565.12 KPA41106.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 DUF1126 PH-like domain zf-C2H2_2 PF12756.7 KPA41107.1 - 1.6e-08 34.8 0.0 3.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) ICMT PF04140.14 KPA41108.1 - 1.2e-07 32.0 0.1 3.1e-06 27.5 0.1 2.4 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KPA41108.1 - 3.4e-07 30.6 0.3 3.6e-06 27.3 0.1 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase HATPase_c PF02518.26 KPA41109.1 - 6.8e-22 78.1 0.0 1.5e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPA41109.1 - 8.9e-16 58.0 0.0 3e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KPA41109.1 - 2e-09 37.3 0.0 5.1e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KPA41109.1 - 0.00028 21.2 0.0 0.00088 19.6 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KPA41109.1 - 0.038 14.3 0.0 0.47 10.8 0.0 2.5 1 1 0 1 1 1 0 GAF domain Kelch_5 PF13854.6 KPA41110.1 - 0.11 12.5 0.9 30 4.8 0.0 3.2 3 0 0 3 3 3 0 Kelch motif TonB_N PF16031.5 KPA41111.1 - 0.033 14.7 6.4 0.033 14.7 6.4 1.8 2 0 0 2 2 2 0 TonB polyproline region Trypan_PARP PF05887.11 KPA41111.1 - 5.3 7.0 11.2 9.8 6.2 11.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Myb_DNA-bind_3 PF12776.7 KPA41112.1 - 8.3e-24 84.4 0.1 1.4e-23 83.7 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MFS_1 PF07690.16 KPA41113.1 - 1.4e-18 66.9 26.4 2.4e-18 66.2 26.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KPA41113.1 - 6.1e-11 42.3 6.7 6.1e-11 42.3 6.7 3.1 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 KPA41113.1 - 2.1e-06 26.9 11.7 6.3e-05 22.0 5.8 2.3 2 0 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KPA41113.1 - 0.005 15.8 7.7 0.005 15.8 7.7 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3493 PF11998.8 KPA41113.1 - 0.022 14.9 0.7 1.8 8.8 1.1 3.0 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 DUF1304 PF06993.12 KPA41113.1 - 6.4 6.8 15.8 0.074 13.0 3.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1304) Fe-S_biosyn PF01521.20 KPA41114.1 - 4.5e-20 71.9 0.0 6.1e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1631 PF07793.11 KPA41114.1 - 1.1 7.6 6.2 1.4 7.3 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DNA_binding_1 PF01035.20 KPA41115.1 - 6.2e-29 100.0 0.0 8.7e-29 99.5 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Luteo_Vpg PF01659.16 KPA41115.1 - 0.11 12.8 1.0 0.15 12.5 1.0 1.3 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein ATP-grasp_2 PF08442.10 KPA41116.1 - 2.7e-77 258.9 0.4 2.7e-77 258.9 0.4 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KPA41116.1 - 1.2e-26 93.3 0.5 1.2e-26 93.3 0.5 1.7 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 KPA41116.1 - 9.5e-10 38.3 0.0 1.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KPA41116.1 - 7.3e-05 22.6 1.0 0.003 17.3 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 KPA41116.1 - 0.034 14.4 0.1 0.86 9.9 0.0 2.7 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Fructosamin_kin PF03881.14 KPA41117.1 - 1.4e-71 241.0 0.0 1.7e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KPA41117.1 - 2.1e-05 24.5 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KPA41117.1 - 0.28 10.0 0.0 0.42 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Snf7 PF03357.21 KPA41118.1 - 1.1e-35 122.8 9.2 1.3e-35 122.6 9.2 1.1 1 0 0 1 1 1 1 Snf7 Holin_BhlA PF10960.8 KPA41118.1 - 0.7 9.9 3.3 6.5 6.8 0.2 2.5 1 1 1 2 2 2 0 BhlA holin family AAA PF00004.29 KPA41119.1 - 1.5e-63 213.1 0.0 1.3e-46 158.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA41119.1 - 1.6e-15 56.6 2.2 2.2e-09 36.9 0.1 3.2 3 0 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 KPA41119.1 - 1.1e-11 45.4 2.5 0.0012 19.3 0.0 5.0 4 3 2 6 6 5 2 AAA ATPase domain AAA_5 PF07728.14 KPA41119.1 - 4.7e-08 33.1 0.1 0.003 17.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KPA41119.1 - 6.6e-08 32.4 0.0 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KPA41119.1 - 2.4e-07 31.1 0.0 0.0046 17.2 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KPA41119.1 - 1.5e-05 25.5 0.0 0.14 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KPA41119.1 - 1.6e-05 24.9 0.7 0.11 12.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KPA41119.1 - 1.9e-05 24.9 0.0 0.0044 17.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KPA41119.1 - 5.1e-05 23.5 0.0 0.00042 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KPA41119.1 - 0.00041 20.7 0.0 0.13 12.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KPA41119.1 - 0.00041 20.0 0.0 0.74 9.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 KPA41119.1 - 0.00044 20.2 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain IstB_IS21 PF01695.17 KPA41119.1 - 0.00089 19.0 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 KPA41119.1 - 0.00093 18.5 0.4 0.06 12.6 0.0 3.2 4 0 0 4 4 3 1 Zeta toxin AAA_28 PF13521.6 KPA41119.1 - 0.001 19.3 0.0 3.8 7.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KPA41119.1 - 0.002 17.5 0.2 0.34 10.2 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KPA41119.1 - 0.0024 17.1 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) TIP49 PF06068.13 KPA41119.1 - 0.0024 17.1 0.0 0.38 9.9 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_17 PF13207.6 KPA41119.1 - 0.0025 18.2 0.0 1.9 8.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 KPA41119.1 - 0.011 15.6 0.0 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KPA41119.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KPA41119.1 - 0.016 15.3 0.0 0.81 9.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KPA41119.1 - 0.018 14.6 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KPA41119.1 - 0.018 15.0 0.0 2.7 7.9 0.0 3.2 3 0 0 3 3 3 0 NACHT domain Sigma54_activat PF00158.26 KPA41119.1 - 0.027 14.2 0.0 0.53 10.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 KPA41119.1 - 0.039 14.0 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KPA41119.1 - 0.04 14.3 0.0 12 6.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 KPA41119.1 - 0.06 13.9 0.0 8 7.0 0.0 2.9 2 0 0 2 2 2 0 ABC transporter Cytidylate_kin PF02224.18 KPA41119.1 - 0.065 13.0 0.0 6.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase TniB PF05621.11 KPA41119.1 - 0.1 12.0 0.0 8.2 5.8 0.0 2.8 3 0 0 3 3 3 0 Bacterial TniB protein Viral_helicase1 PF01443.18 KPA41119.1 - 0.11 12.2 0.0 0.97 9.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KPA41119.1 - 0.14 12.1 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 NTPase Cytochrom_C PF00034.21 KPA41120.1 - 1.6e-11 45.1 0.0 2.2e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KPA41120.1 - 3.5e-09 36.9 1.5 1.2e-08 35.1 1.5 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KPA41120.1 - 0.011 15.5 2.4 0.05 13.3 2.4 2.2 1 1 0 1 1 1 0 Cytochrome c-550 domain RNase_PH PF01138.21 KPA41122.1 - 1.4e-15 58.0 0.0 2.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KPA41122.1 - 0.0057 16.7 0.1 0.01 15.9 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 ATE_C PF04377.15 KPA41123.1 - 6.2e-46 156.3 0.4 1.1e-45 155.5 0.1 1.6 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KPA41123.1 - 3.7e-09 36.9 1.9 8.5e-09 35.7 1.9 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus NUDIX PF00293.28 KPA41125.1 - 2e-19 70.0 0.8 2.3e-19 69.7 0.8 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 KPA41125.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase LSM PF01423.22 KPA41126.1 - 1.2e-14 53.8 0.0 2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 LSM domain MMU163 PF17119.5 KPA41127.1 - 6.6e-67 225.3 3.8 6.3e-49 166.4 1.1 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis zf-C2H2_assoc PF16606.5 KPA41127.1 - 0.14 12.4 0.5 0.86 9.9 0.3 2.1 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers Ras PF00071.22 KPA41128.1 - 1.5e-65 219.8 0.4 1.7e-65 219.5 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA41128.1 - 7.3e-36 123.0 0.1 1.3e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA41128.1 - 3.4e-16 59.2 0.1 4e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KPA41128.1 - 2.3e-05 24.4 0.0 0.0001 22.3 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA41128.1 - 2.9e-05 24.0 0.8 0.13 12.1 0.0 2.5 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KPA41128.1 - 8.7e-05 22.1 0.3 0.00024 20.7 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KPA41128.1 - 0.00027 20.4 0.1 0.00034 20.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KPA41128.1 - 0.00044 19.7 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KPA41128.1 - 0.00094 19.6 0.0 0.15 12.5 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KPA41128.1 - 0.004 16.7 0.0 0.023 14.2 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KPA41128.1 - 0.0091 16.4 0.0 0.012 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA41128.1 - 0.044 14.0 0.0 0.069 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KPA41128.1 - 0.055 12.7 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 KPA41128.1 - 0.056 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KPA41128.1 - 0.073 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 KPA41128.1 - 0.08 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KPA41128.1 - 0.082 12.9 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KPA41128.1 - 0.086 13.3 0.1 0.15 12.6 0.1 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 KPA41128.1 - 0.1 12.3 0.1 1.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KPA41128.1 - 0.12 11.9 0.1 1.6 8.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Use1 PF09753.9 KPA41129.1 - 0.076 12.7 3.0 0.076 12.7 3.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 FemAB PF02388.16 KPA41129.1 - 0.35 9.7 2.5 0.44 9.4 2.5 1.0 1 0 0 1 1 1 0 FemAB family WD40 PF00400.32 KPA41131.1 - 7.1e-13 48.8 11.1 0.015 16.2 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Sigma70_r1_2 PF00140.20 KPA41131.1 - 0.017 15.1 0.3 0.032 14.3 0.3 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Kelch_6 PF13964.6 KPA41131.1 - 0.053 13.8 0.1 9.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Kelch motif DUF3494 PF11999.8 KPA41131.1 - 0.053 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) Mcl1_mid PF12341.8 KPA41132.1 - 1.7e-102 342.8 0.0 1.2e-98 330.1 0.0 2.4 2 0 0 2 2 2 2 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KPA41132.1 - 3.5e-23 81.4 0.3 4.7e-08 33.6 0.0 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA41132.1 - 1.3e-19 70.3 0.0 0.00016 21.9 0.0 7.0 2 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KPA41132.1 - 5.1e-07 29.1 0.0 1.2e-06 27.8 0.0 1.5 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 KPA41132.1 - 6.7e-05 22.9 0.2 0.022 14.7 0.1 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KPA41132.1 - 0.026 13.8 0.0 0.24 10.7 0.0 2.1 1 1 0 1 1 1 0 WD40-like domain WD40_3 PF15911.5 KPA41132.1 - 0.027 14.5 0.0 13 5.9 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat IKI3 PF04762.12 KPA41132.1 - 0.03 12.4 0.2 0.077 11.0 0.1 1.5 1 1 0 1 1 1 0 IKI3 family Ge1_WD40 PF16529.5 KPA41132.1 - 0.035 13.1 0.0 9.1 5.1 0.0 2.8 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_pol_alpha_N PF12254.8 KPA41132.1 - 8.1 6.6 9.4 0.79 9.8 3.9 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal HSF_DNA-bind PF00447.17 KPA41133.1 - 5.1e-29 100.7 0.6 9e-29 99.9 0.6 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3320 PF11784.8 KPA41133.1 - 0.11 12.5 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) NICE-3 PF07406.11 KPA41135.1 - 0.003 17.6 0.3 0.014 15.4 0.1 2.0 2 0 0 2 2 2 1 NICE-3 protein DUF4129 PF13559.6 KPA41135.1 - 0.0048 17.1 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Ndc1_Nup PF09531.10 KPA41136.1 - 5e-202 672.9 6.8 5.6e-202 672.7 6.8 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 KPA41137.1 - 6e-24 84.4 4.3 6e-24 84.4 4.3 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KPA41137.1 - 1.5e-09 37.7 2.5 1.8e-09 37.5 0.9 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KPA41137.1 - 0.0013 18.4 13.8 0.0013 18.4 13.8 2.0 2 1 0 2 2 2 1 Syntaxin DUF883 PF05957.13 KPA41137.1 - 0.01 16.4 12.8 0.021 15.4 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Synaptobrevin PF00957.21 KPA41137.1 - 0.077 12.8 3.3 0.052 13.3 0.9 2.0 2 0 0 2 2 2 0 Synaptobrevin T2SSF PF00482.23 KPA41137.1 - 0.37 10.8 4.3 0.3 11.1 1.5 2.4 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F DUF2205 PF10224.9 KPA41137.1 - 0.37 10.8 0.1 0.37 10.8 0.1 3.2 4 0 0 4 4 4 0 Short coiled-coil protein DUF5345 PF17280.2 KPA41137.1 - 0.87 9.6 8.3 4.2 7.4 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5345) Occludin_ELL PF07303.13 KPA41137.1 - 1.3 9.8 5.7 1.5 9.5 1.1 2.7 2 1 0 2 2 2 0 Occludin homology domain 60KD_IMP PF02096.20 KPA41138.1 - 0.00012 22.1 0.0 0.00018 21.5 0.0 1.4 1 1 0 1 1 1 1 60Kd inner membrane protein Tfb4 PF03850.14 KPA41139.1 - 8.4e-96 320.7 0.0 9.7e-96 320.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 TackOD1 PF18551.1 KPA41139.1 - 0.014 15.1 0.4 0.022 14.4 0.4 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Rogdi_lz PF10259.9 KPA41139.1 - 0.021 14.3 0.3 0.037 13.5 0.3 1.4 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein UNC45-central PF11701.8 KPA41140.1 - 7.4e-54 181.9 0.0 5.2e-53 179.1 0.0 2.5 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central Arm PF00514.23 KPA41140.1 - 0.086 12.9 4.6 28 4.9 0.0 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat tRNA_U5-meth_tr PF05958.11 KPA41141.1 - 6.9e-15 54.9 0.0 1.7e-13 50.3 0.0 2.6 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KPA41141.1 - 8.5e-09 35.2 0.0 2.8e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KPA41141.1 - 3.2e-05 23.8 0.0 6.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA41141.1 - 7.6e-05 23.3 0.0 0.00021 21.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA41141.1 - 0.033 14.9 0.0 0.09 13.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KPA41141.1 - 0.099 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 G_glu_transpept PF01019.21 KPA41142.1 - 8.5e-168 559.3 0.0 9.8e-168 559.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1344 PF07076.11 KPA41142.1 - 0.068 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) ALG11_N PF15924.5 KPA41143.1 - 1.2e-85 286.8 0.0 1.8e-85 286.2 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KPA41143.1 - 3.5e-19 69.0 0.0 5.6e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KPA41143.1 - 1.7e-10 41.5 0.0 3.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KPA41143.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 HET PF06985.11 KPA41144.1 - 1.9e-22 80.2 0.0 3.7e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TMEM100 PF16311.5 KPA41146.1 - 0.0017 18.0 0.2 0.068 12.8 0.0 2.3 2 0 0 2 2 2 1 Transmembrane protein 100 MLANA PF14991.6 KPA41146.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A Dec-1 PF04624.14 KPA41146.1 - 0.067 13.0 0.3 0.15 12.0 0.3 1.5 1 0 0 1 1 1 0 Dec-1 repeat TMEM154 PF15102.6 KPA41146.1 - 0.12 12.3 1.6 0.37 10.7 1.6 1.8 1 1 0 1 1 1 0 TMEM154 protein family DUF3149 PF11346.8 KPA41146.1 - 0.18 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) FeoB_associated PF12669.7 KPA41146.1 - 0.4 11.1 0.1 0.4 11.1 0.1 2.4 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Git3 PF11710.8 KPA41147.1 - 1.1e-57 195.1 15.5 1.4e-57 194.8 15.5 1.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KPA41147.1 - 0.023 14.0 5.2 0.033 13.5 4.8 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 KPA41148.1 - 3.2e-21 75.2 0.4 4.9e-21 74.6 0.4 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term GATase PF00117.28 KPA41149.1 - 4.6e-12 46.1 0.0 6.2e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KPA41149.1 - 0.0066 16.1 0.0 0.0092 15.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain RSN1_7TM PF02714.15 KPA41150.1 - 5.9e-76 255.4 24.0 5.9e-76 255.4 24.0 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KPA41150.1 - 3.2e-43 147.2 0.1 3.2e-43 147.2 0.1 3.7 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KPA41150.1 - 5.1e-28 98.5 2.8 2e-15 57.5 0.2 2.6 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KPA41150.1 - 7.9e-16 58.0 0.0 2.1e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter SRP_SPB PF02978.19 KPA41150.1 - 0.0077 16.8 0.4 0.018 15.6 0.4 1.6 1 0 0 1 1 1 1 Signal peptide binding domain Abhydrolase_1 PF00561.20 KPA41151.1 - 6.9e-23 81.6 0.0 2.5e-22 79.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA41151.1 - 8.1e-14 51.5 0.0 6.2e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA41151.1 - 4.7e-13 50.3 0.0 1.8e-12 48.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 KPA41151.1 - 3.9e-06 26.4 0.0 1.1e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KPA41151.1 - 0.00033 20.4 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 KPA41151.1 - 0.0097 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 KPA41151.1 - 0.02 14.6 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KPA41151.1 - 0.05 13.5 0.0 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KPA41151.1 - 0.087 12.5 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.25 KPA41151.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 KPA41151.1 - 0.16 11.7 0.0 10 5.8 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KPA41151.1 - 0.23 10.3 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Spo7 PF03907.13 KPA41152.1 - 1.8e-93 312.1 0.1 2.6e-93 311.5 0.1 1.2 1 0 0 1 1 1 1 Spo7-like protein Ank_2 PF12796.7 KPA41153.1 - 4.7e-20 72.0 0.0 5.7e-08 33.2 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA41153.1 - 8.5e-17 59.5 0.4 5.2e-08 32.5 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KPA41153.1 - 5.6e-16 58.7 2.0 1.4e-06 28.7 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA41153.1 - 2.2e-14 53.3 1.2 0.002 18.4 0.0 5.6 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KPA41153.1 - 5.9e-13 48.6 1.1 8.6e-05 22.8 0.0 5.1 4 1 0 4 4 4 3 Ankyrin repeat F-box-like PF12937.7 KPA41153.1 - 1.4e-07 31.2 0.5 2.7e-07 30.4 0.5 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KPA41153.1 - 0.0059 16.5 0.1 0.0098 15.8 0.1 1.3 1 0 0 1 1 1 1 F-box F-box PF00646.33 KPA41153.1 - 0.0095 15.8 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 KPA41154.1 - 9.3e-35 120.2 26.0 9.3e-35 120.2 26.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KPA41154.1 - 3.6 7.4 10.2 8.3 6.2 4.5 2.8 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SNF2_N PF00176.23 KPA41155.1 - 1.7e-65 221.0 0.5 1.7e-65 221.0 0.5 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA41155.1 - 6.9e-22 77.9 0.3 4.3e-21 75.3 0.0 2.5 3 1 1 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA41155.1 - 5.5e-10 39.5 0.7 1.1e-09 38.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KPA41155.1 - 0.002 17.8 0.0 0.0065 16.2 0.0 1.9 1 1 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 KPA41155.1 - 0.0023 17.2 0.0 0.0023 17.2 0.0 2.3 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AT_hook PF02178.19 KPA41155.1 - 1 9.5 9.9 4.3 7.5 9.9 2.2 1 0 0 1 1 1 0 AT hook motif tRNA_bind PF01588.20 KPA41156.1 - 1.5e-21 76.3 0.2 4.9e-21 74.6 0.2 1.9 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KPA41156.1 - 7.4e-05 22.7 0.0 0.00022 21.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA41156.1 - 0.00035 20.7 1.0 0.003 17.7 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KPA41156.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SPATIAL PF15256.6 KPA41156.1 - 0.071 13.4 2.6 0.1 12.9 1.2 1.8 2 0 0 2 2 2 0 SPATIAL GST_C_3 PF14497.6 KPA41156.1 - 0.075 13.2 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RNA_pol PF00940.19 KPA41157.1 - 8e-182 604.7 0.0 1.3e-181 604.0 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KPA41157.1 - 7e-94 315.0 1.4 1.1e-93 314.3 1.4 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DUF4110 PF13422.6 KPA41157.1 - 1.1 9.3 5.0 0.28 11.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) RsfS PF02410.15 KPA41158.1 - 8.2e-12 45.4 0.0 1.8e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation DHHA2 PF02833.14 KPA41159.1 - 7.9e-40 136.4 0.1 1.3e-39 135.6 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KPA41159.1 - 7.7e-09 35.7 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 DHH family zinc_ribbon_16 PF17034.5 KPA41161.1 - 0.017 15.3 1.1 0.038 14.2 1.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family Prok-RING_4 PF14447.6 KPA41162.1 - 2.6e-06 27.2 9.0 1.5e-05 24.7 5.7 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KPA41162.1 - 0.00031 20.6 5.2 0.00031 20.6 5.2 2.7 4 0 0 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPA41162.1 - 0.00082 19.3 10.8 0.012 15.6 1.9 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 KPA41162.1 - 0.0011 19.3 7.1 0.0011 19.3 7.1 3.0 3 1 0 3 3 3 1 Ring finger domain DUF4796 PF16044.5 KPA41162.1 - 0.0019 17.8 1.6 1.5 8.4 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4796) zf-C3HC4_3 PF13920.6 KPA41162.1 - 0.011 15.5 7.8 0.011 15.5 7.8 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA41163.1 - 8.5e-06 25.7 0.8 8.5e-06 25.7 0.8 3.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KPA41163.1 - 0.00012 22.3 2.3 0.00012 22.3 2.3 2.9 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 KPA41163.1 - 0.00083 19.6 2.5 0.00083 19.6 2.5 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KPA41163.1 - 0.0018 18.2 2.9 0.0018 18.2 2.9 2.4 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KPA41163.1 - 0.0092 15.8 3.2 0.0092 15.8 3.2 2.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 BBP1_C PF15272.6 KPA41163.1 - 0.036 13.9 0.1 0.056 13.3 0.1 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal zf-C3HC4_2 PF13923.6 KPA41163.1 - 0.09 12.6 0.2 0.09 12.6 0.2 3.8 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KPA41163.1 - 1.4 9.1 4.3 2.8 8.1 0.8 2.6 3 0 0 3 3 3 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KPA41163.1 - 2.5 7.9 8.5 0.54 10.0 0.2 3.4 3 0 0 3 3 3 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 KPA41163.1 - 9 6.3 12.7 0.14 12.1 3.2 2.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Fringe PF02434.16 KPA41164.1 - 0.00049 19.6 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 Fringe-like SLATT_fungal PF18142.1 KPA41165.1 - 3.9e-26 91.4 0.0 5e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain NAD_Gly3P_dh_N PF01210.23 KPA41166.1 - 4.5e-47 159.9 0.0 1.2e-46 158.5 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KPA41166.1 - 1.7e-43 148.3 0.5 2.7e-43 147.6 0.5 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KPA41166.1 - 0.054 14.1 0.0 14 6.3 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AIG2_2 PF13772.6 KPA41167.1 - 0.0018 18.6 0.0 0.016 15.6 0.0 2.3 2 0 0 2 2 2 1 AIG2-like family DUF4173 PF13777.6 KPA41167.1 - 0.18 11.2 1.9 0.27 10.6 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Peptidase_C48 PF02902.19 KPA41169.1 - 9.1e-19 68.2 0.0 5.2e-18 65.7 0.0 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SLX9 PF15341.6 KPA41171.1 - 2.8e-36 124.8 12.4 4.2e-36 124.2 12.4 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 ThiF PF00899.21 KPA41172.1 - 8.8e-59 198.8 0.0 1.3e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KPA41172.1 - 8.6e-10 39.1 0.0 2.3e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 KPA41172.1 - 0.0017 18.4 0.1 0.016 15.3 0.0 2.5 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KPA41172.1 - 0.076 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF641 PF04859.12 KPA41172.1 - 0.18 12.1 1.9 0.31 11.4 1.9 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Pam17 PF08566.10 KPA41173.1 - 9.3e-64 214.2 0.0 1.2e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 EAF PF09816.9 KPA41175.1 - 2.2e-20 72.9 1.6 2.7e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Senescence_reg PF04520.13 KPA41175.1 - 0.0066 17.3 7.9 0.0066 17.3 7.9 2.0 2 1 0 2 2 2 1 Senescence regulator DUF4551 PF15087.6 KPA41175.1 - 2.6 6.8 4.7 3.2 6.5 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GFA PF04828.14 KPA41176.1 - 3.9e-15 55.9 0.7 5.9e-15 55.4 0.7 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme G6PD_bact PF10786.9 KPA41176.1 - 0.024 14.2 0.5 0.034 13.7 0.5 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) POP1 PF06978.11 KPA41177.1 - 5.1e-74 248.7 11.4 5.1e-74 248.7 11.4 1.8 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KPA41177.1 - 2.8e-30 104.5 0.1 7.1e-30 103.2 0.1 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain MEDS PF14417.6 KPA41177.1 - 0.18 11.6 0.1 0.41 10.5 0.1 1.5 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain NT-C2 PF10358.9 KPA41178.1 - 9.4e-26 90.3 0.0 4.5e-25 88.1 0.0 1.9 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Transformer PF06495.11 KPA41178.1 - 0.98 9.5 9.9 4.9 7.2 9.5 2.0 2 0 0 2 2 2 0 Fruit fly transformer protein HSP70 PF00012.20 KPA41179.1 - 4.5e-78 262.9 2.3 4.5e-78 262.9 2.3 1.3 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KPA41179.1 - 5e-10 38.7 0.2 8.1e-10 38.0 0.2 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.6 KPA41179.1 - 0.0049 16.6 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein Rrp40_N PF18311.1 KPA41180.1 - 2.4e-17 62.6 0.8 9.1e-17 60.7 0.5 2.1 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 KPA41180.1 - 7.6e-16 58.2 0.1 1.8e-15 57.0 0.1 1.7 1 0 0 1 1 1 1 KH domain HIRAN PF08797.11 KPA41180.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain zf-C2H2 PF00096.26 KPA41181.1 - 5.8e-05 23.3 30.3 0.009 16.4 2.6 4.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA41181.1 - 7.7e-05 23.2 15.4 0.019 15.8 1.7 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KPA41181.1 - 0.0032 18.0 11.5 0.036 14.7 1.2 3.3 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-Di19 PF05605.12 KPA41181.1 - 0.023 15.0 2.2 0.023 15.0 2.2 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_aberr PF17017.5 KPA41181.1 - 0.033 14.3 3.9 0.045 13.9 0.5 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger Adeno_E3_CR2 PF02439.15 KPA41181.1 - 0.071 12.9 3.4 0.14 12.0 3.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Sina PF03145.16 KPA41181.1 - 5.2 7.0 12.4 3.2 7.7 10.4 1.5 1 1 0 1 1 1 0 Seven in absentia protein family AAA_12 PF13087.6 KPA41182.1 - 2.1e-21 76.5 0.0 3.5e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPA41182.1 - 3.5e-12 46.7 0.0 5.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KPA41182.1 - 7.3e-08 32.1 0.3 4.2e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KPA41182.1 - 5.1e-05 23.1 0.0 0.0082 15.9 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 KPA41182.1 - 0.15 11.4 0.0 0.65 9.3 0.0 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain DNA_methylase PF00145.17 KPA41183.1 - 4.5e-38 131.4 0.0 3.9e-26 92.2 0.0 2.1 1 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase HhH-GPD PF00730.25 KPA41185.1 - 2.3e-06 28.0 0.0 4.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.6 KPA41185.1 - 0.045 14.4 0.0 0.15 12.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain SEN1_N PF12726.7 KPA41186.1 - 3.5e-207 690.1 1.8 4.6e-207 689.8 1.8 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KPA41186.1 - 1.3e-71 241.5 0.8 1.3e-71 241.5 0.8 2.7 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KPA41186.1 - 2.1e-61 207.1 0.0 3.6e-61 206.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPA41186.1 - 1e-08 35.1 0.4 3.4e-05 23.6 0.3 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KPA41186.1 - 3.1e-08 34.1 0.0 1.1e-07 32.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KPA41186.1 - 9.3e-05 22.1 3.6 0.0038 16.8 0.8 3.3 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KPA41186.1 - 0.00015 21.6 0.1 0.21 11.3 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KPA41186.1 - 0.019 15.3 0.1 0.15 12.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KPA41186.1 - 0.19 11.5 0.9 1.8 8.3 0.1 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase GrpE PF01025.19 KPA41187.1 - 0.12 12.1 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 GrpE adh_short PF00106.25 KPA41188.1 - 5e-08 32.6 0.0 0.0014 18.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA41188.1 - 8.9e-06 25.4 0.0 0.0003 20.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA41188.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 KR domain fn3_2 PF16893.5 KPA41189.1 - 1e-39 134.5 0.0 1.8e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KPA41189.1 - 2.5e-23 81.7 0.8 4.4e-23 81.0 0.8 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KPA41189.1 - 8.6e-13 48.0 0.0 1.5e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KPA41189.1 - 1.1e-10 41.7 0.0 2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KPA41189.1 - 2.6e-05 24.5 0.0 6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 KPA41189.1 - 0.0011 19.1 0.7 0.0044 17.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 KPA41189.1 - 0.0035 17.6 0.0 0.015 15.6 0.0 2.0 1 1 0 1 1 1 1 Fibronectin type III domain eIF-1a PF01176.19 KPA41191.1 - 4.9e-21 74.3 0.0 6.8e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.23 KPA41192.1 - 8.5e-30 103.0 0.4 1.1e-29 102.5 0.4 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KPA41192.1 - 0.00038 20.2 0.3 0.00084 19.1 0.3 1.6 1 0 0 1 1 1 1 WH2 motif DCP1 PF06058.13 KPA41192.1 - 0.027 14.4 0.2 0.039 13.9 0.2 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family ERCC4 PF02732.15 KPA41193.1 - 2e-19 70.3 0.0 4.3e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain DUF4780 PF16012.5 KPA41193.1 - 0.034 13.6 0.0 3.8 6.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4780) CorA PF01544.18 KPA41195.1 - 2.9e-15 56.4 0.2 5.3e-15 55.5 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RHH_3 PF12651.7 KPA41195.1 - 0.7 9.9 2.5 1.5 8.8 0.3 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix domain Cyclin PF08613.11 KPA41197.1 - 1.5e-07 31.9 0.7 1.5e-07 31.9 0.7 2.5 2 2 1 3 3 3 1 Cyclin Cyclin_N PF00134.23 KPA41197.1 - 0.00039 20.2 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain DEAD PF00270.29 KPA41198.1 - 5.6e-39 133.7 0.1 9.8e-39 132.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA41198.1 - 9.6e-25 87.1 0.4 3.3e-23 82.1 0.3 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA41198.1 - 2.3e-08 34.3 0.0 5.4e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 KPA41198.1 - 0.045 14.3 0.6 0.12 12.9 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Rpr2 PF04032.16 KPA41199.1 - 5.1e-24 84.4 2.6 1.1e-23 83.3 2.6 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Stc1 PF12898.7 KPA41199.1 - 0.058 13.9 4.3 0.12 12.9 3.1 2.1 1 1 1 2 2 2 0 Stc1 domain DASH_Hsk3 PF08227.11 KPA41200.1 - 3.4e-20 72.1 4.6 4.6e-20 71.7 4.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like LPP PF04728.13 KPA41200.1 - 0.023 15.1 0.8 0.035 14.5 0.8 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper ApbA PF02558.16 KPA41202.1 - 7.6e-27 93.8 0.0 1.2e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KPA41202.1 - 7.7e-21 74.6 0.0 1.2e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal AAA PF00004.29 KPA41203.1 - 5.9e-15 55.9 0.0 1.6e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA41203.1 - 0.0061 16.8 2.7 0.099 12.9 0.2 2.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA41203.1 - 0.028 14.8 0.7 0.16 12.3 0.7 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KPA41203.1 - 0.047 13.7 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KPA41203.1 - 0.12 12.1 0.0 0.12 12.1 0.0 4.3 3 2 0 3 3 3 0 AAA domain End_beta_barrel PF12195.8 KPA41204.1 - 0.038 13.9 0.2 0.13 12.2 0.2 1.8 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase X8 PF07983.13 KPA41204.1 - 0.81 10.4 4.3 14 6.4 0.1 2.4 2 0 0 2 2 2 0 X8 domain GRDP-like PF07173.12 KPA41206.1 - 4.2e-17 63.1 0.0 1.4e-16 61.4 0.0 1.9 1 1 1 2 2 2 1 Glycine-rich domain-containing protein-like DUF1912 PF08930.10 KPA41206.1 - 0.058 13.6 1.4 0.094 12.9 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) Lipase_3 PF01764.25 KPA41207.1 - 2.7e-09 37.0 0.0 4e-08 33.2 0.0 2.5 2 1 1 3 3 3 1 Lipase (class 3) DUF3433 PF11915.8 KPA41208.1 - 3.2e-20 72.4 28.0 9.5e-16 58.0 1.7 3.8 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) COX2_TM PF02790.15 KPA41208.1 - 0.0066 16.6 0.7 0.0066 16.6 0.7 2.6 3 0 0 3 3 3 1 Cytochrome C oxidase subunit II, transmembrane domain Spore_III_AB PF09548.10 KPA41208.1 - 0.18 11.9 0.4 3.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) 2-oxoacid_dh PF00198.23 KPA41209.1 - 5.6e-76 255.0 0.1 7.2e-76 254.7 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KPA41209.1 - 1.6e-18 66.3 1.2 3.9e-18 65.0 1.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KPA41209.1 - 1.6e-10 41.1 0.9 5.5e-10 39.4 0.9 2.0 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 KPA41209.1 - 0.0074 16.8 2.4 0.0093 16.5 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3614) Calycin_like PF13944.6 KPA41209.1 - 0.079 13.3 0.3 0.55 10.5 0.1 2.5 2 1 1 3 3 3 0 Calycin-like beta-barrel domain Fungal_trans PF04082.18 KPA41210.1 - 4.4e-14 52.2 0.8 7.6e-14 51.4 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SinI PF08671.10 KPA41210.1 - 0.063 13.1 0.1 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Anti-repressor SinI DUF3682 PF12446.8 KPA41210.1 - 8.4 6.9 12.8 15 6.1 12.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF1308 PF07000.11 KPA41211.1 - 1.1e-08 35.2 0.0 5.3e-07 29.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) MtrF PF09472.10 KPA41211.1 - 0.22 10.9 0.0 1 8.8 0.0 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Sec7 PF01369.20 KPA41212.1 - 9.1e-70 234.1 3.8 2.5e-69 232.6 0.5 3.0 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 KPA41212.1 - 3.6e-40 137.5 1.8 3.6e-40 137.5 1.8 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KPA41212.1 - 9.7e-33 111.9 13.2 2.1e-32 110.8 0.1 5.7 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 KPA41212.1 - 7.5e-23 81.1 4.7 7.2e-22 77.9 0.8 3.4 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 RNA_pol_3_Rpc31 PF11705.8 KPA41214.1 - 2.4e-63 214.4 2.6 3.1e-63 214.1 2.6 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Nucleoporin_FG PF13634.6 KPA41215.1 - 2.4e-12 47.5 134.3 6.5e-06 26.9 38.1 4.2 2 1 2 4 4 4 3 Nucleoporin FG repeat region Laminin_II PF06009.12 KPA41215.1 - 0.23 11.5 2.2 0.83 9.7 0.5 2.4 2 1 0 2 2 2 0 Laminin Domain II Fip1 PF05182.13 KPA41216.1 - 1.4e-20 72.5 1.0 2.5e-20 71.7 1.0 1.5 1 0 0 1 1 1 1 Fip1 motif DNA_pol_phi PF04931.13 KPA41216.1 - 2.5 6.1 10.2 3.1 5.8 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi SGL PF08450.12 KPA41217.1 - 1.9e-06 27.7 0.2 0.0025 17.5 0.1 2.3 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 KPA41217.1 - 0.0017 18.8 3.4 0.14 12.7 0.0 4.2 3 1 0 3 3 3 1 PQQ-like domain PQQ PF01011.21 KPA41217.1 - 0.026 14.5 0.5 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat PIF1 PF05970.14 KPA41217.1 - 0.2 10.8 0.1 0.3 10.2 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase Peptidase_M50B PF13398.6 KPA41219.1 - 2.7e-58 196.9 20.1 3.4e-58 196.6 20.1 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 KPA41219.1 - 0.061 12.6 0.2 0.15 11.3 0.2 1.6 1 0 0 1 1 1 0 Peptidase family M50 Peptidase_M36 PF02128.15 KPA41219.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) MLANA PF14991.6 KPA41219.1 - 1.8 8.9 9.2 0.14 12.5 0.8 2.8 2 1 1 3 3 3 0 Protein melan-A Methyltransf_31 PF13847.6 KPA41220.1 - 1.2e-06 28.4 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA41220.1 - 6.5e-06 26.8 0.1 1e-05 26.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KPA41220.1 - 0.021 14.5 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DsbB PF02600.16 KPA41221.1 - 0.0038 17.7 0.9 0.42 11.0 0.6 2.5 2 1 0 2 2 2 2 Disulfide bond formation protein DsbB Ctr PF04145.15 KPA41221.1 - 0.017 15.7 0.9 0.017 15.7 0.9 2.0 2 0 0 2 2 2 0 Ctr copper transporter family DUF5533 PF17685.1 KPA41221.1 - 3.4 8.1 8.3 0.15 12.5 0.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5533) GST_C_3 PF14497.6 KPA41222.1 - 1.7e-29 101.9 0.6 2.9e-29 101.2 0.6 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA41222.1 - 0.00027 21.1 0.2 0.0007 19.8 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPA41222.1 - 0.00094 19.2 0.0 0.0025 17.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KPA41222.1 - 0.0013 19.0 0.0 0.0045 17.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF3433 PF11915.8 KPA41223.1 - 1.8e-29 102.0 11.0 8.2e-19 67.9 5.9 3.9 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) DUF1418 PF07214.12 KPA41223.1 - 4.9 7.1 5.2 2.1 8.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) CRCB PF02537.15 KPA41224.1 - 1.1e-39 134.6 16.9 6.9e-23 80.8 8.3 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) UPRTase PF14681.6 KPA41225.1 - 6.3e-77 257.7 0.0 7.2e-77 257.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KPA41225.1 - 1.4e-06 27.9 0.0 2.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.17 KPA41225.1 - 0.0059 15.9 0.0 0.42 9.9 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase DNA_ligase_A_M PF01068.21 KPA41226.1 - 1.6e-45 155.3 0.0 3.2e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KPA41226.1 - 8.2e-43 146.7 0.0 2.4e-42 145.2 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus RNA_ligase PF09414.10 KPA41226.1 - 3.2e-19 69.8 0.0 9.3e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 RNA ligase BRCT_2 PF16589.5 KPA41226.1 - 9.1e-17 61.3 0.0 5.4e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KPA41226.1 - 3.3e-14 53.3 1.8 1.3e-13 51.4 0.0 2.8 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 KPA41226.1 - 1.4e-08 35.0 0.1 3e-06 27.5 0.0 2.9 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KPA41226.1 - 1.9e-05 24.8 0.0 0.00028 21.1 0.0 2.3 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain DNA_ligase_IV PF11411.8 KPA41226.1 - 0.0018 18.4 0.0 0.0046 17.1 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV RTT107_BRCT_5 PF16770.5 KPA41226.1 - 0.045 13.6 0.0 5.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain mRNA_cap_enzyme PF01331.19 KPA41226.1 - 0.065 13.0 0.1 0.51 10.1 0.0 2.4 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain CorA PF01544.18 KPA41227.1 - 1.6e-25 90.0 4.9 1.8e-21 76.8 1.6 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein HAD_2 PF13419.6 KPA41228.1 - 1.8e-11 44.5 0.0 2.3e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA41228.1 - 2e-09 38.1 0.0 6e-09 36.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA41228.1 - 6.4e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like MFS_1 PF07690.16 KPA41229.1 - 2.4e-47 161.6 30.2 2.4e-47 161.6 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA41229.1 - 9.2e-14 51.1 8.6 9.2e-14 51.1 8.6 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KPA41229.1 - 6.7e-08 31.4 2.9 1.2e-07 30.6 2.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KPA41229.1 - 1.1e-05 24.1 3.5 1.9e-05 23.3 3.5 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2721 PF11026.8 KPA41229.1 - 8.5 6.3 12.2 10 6.0 1.9 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2721) Fungal_trans PF04082.18 KPA41230.1 - 1.4e-24 86.6 0.0 2.3e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_30 PF13556.6 KPA41230.1 - 0.079 12.8 0.0 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain AAA PF00004.29 KPA41231.1 - 5.5e-17 62.4 0.0 3.2e-16 59.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA41231.1 - 9.3e-05 22.7 2.2 0.0024 18.2 0.1 3.2 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.6 KPA41231.1 - 0.00064 20.1 0.0 0.0018 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KPA41231.1 - 0.00072 19.6 0.0 0.0027 17.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KPA41231.1 - 0.0014 18.4 0.1 0.0039 16.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPA41231.1 - 0.0065 16.8 0.3 0.035 14.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPA41231.1 - 0.0091 16.2 0.2 0.023 14.8 0.2 2.0 1 1 0 1 1 1 1 AAA domain Kinesin PF00225.23 KPA41231.1 - 0.035 13.0 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain IstB_IS21 PF01695.17 KPA41231.1 - 0.041 13.6 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Vps36_ESCRT-II PF11605.8 KPA41231.1 - 0.042 14.0 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AAA_28 PF13521.6 KPA41231.1 - 0.088 13.0 0.3 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 KPA41231.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_24 PF13479.6 KPA41231.1 - 0.23 11.2 1.7 0.99 9.1 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 KPA41231.1 - 0.69 9.7 4.9 0.46 10.2 0.2 2.3 2 1 0 2 2 2 0 AAA domain p450 PF00067.22 KPA41232.1 - 1.7e-66 224.9 0.0 6.4e-58 196.6 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 NAD_binding_1 PF00175.21 KPA41233.1 - 5.1e-32 110.8 0.0 9.1e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KPA41233.1 - 1.3e-27 96.0 0.0 2.1e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KPA41233.1 - 3.8e-22 78.2 0.1 7.8e-22 77.2 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KPA41233.1 - 1.5e-05 25.2 0.0 0.0025 18.0 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KPA41233.1 - 0.018 15.2 0.0 5.6 7.2 0.0 2.5 1 1 0 2 2 2 0 Siderophore-interacting FAD-binding domain 3HCDH_N PF02737.18 KPA41234.1 - 2e-28 99.5 0.0 3.3e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KPA41234.1 - 5.7e-15 55.7 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KPA41234.1 - 0.00013 22.0 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KPA41234.1 - 0.0015 18.7 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KPA41234.1 - 0.0054 17.3 0.0 0.0099 16.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KPA41234.1 - 0.047 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_deac_1 PF01522.21 KPA41236.1 - 8.5e-27 93.5 0.0 2.4e-26 92.0 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KPA41236.1 - 1.8e-09 37.3 0.0 2.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 KPA41236.1 - 0.011 15.4 0.3 0.04 13.6 0.3 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Creatininase PF02633.14 KPA41236.1 - 0.023 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Creatinine amidohydrolase p450 PF00067.22 KPA41238.1 - 5.4e-38 130.9 0.0 2.6e-27 95.7 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 TRI12 PF06609.13 KPA41239.1 - 0 1219.4 22.9 0 1219.1 22.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPA41239.1 - 3.1e-22 79.0 37.0 3.1e-22 79.0 37.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA41239.1 - 7.5e-08 31.7 7.4 7.5e-08 31.7 7.4 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter DUF3040 PF11239.8 KPA41239.1 - 1.5 9.2 0.0 1.5 9.2 0.0 4.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) p450 PF00067.22 KPA41240.1 - 9.1e-66 222.5 0.0 1.1e-65 222.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRI9 PF08195.11 KPA41241.1 - 1.1e-32 111.6 7.1 1.2e-32 111.5 7.1 1.0 1 0 0 1 1 1 1 TRI9 protein DUF4235 PF14019.6 KPA41241.1 - 0.019 15.1 0.5 0.021 14.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) Fungal_trans_2 PF11951.8 KPA41242.1 - 2.1e-73 247.3 3.9 2.4e-73 247.1 3.9 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain PilO PF04350.13 KPA41242.1 - 0.087 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Pilus assembly protein, PilO TRI5 PF06330.11 KPA41243.1 - 1.2e-194 646.2 4.8 1.4e-194 646.0 4.8 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF1816 PF08846.10 KPA41243.1 - 0.0049 16.9 0.1 0.016 15.2 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1816) USP7_ICP0_bdg PF12436.8 KPA41243.1 - 0.028 13.8 4.0 0.034 13.5 2.0 2.2 2 1 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 DUF2935 PF11155.8 KPA41243.1 - 0.086 13.2 2.5 0.095 13.0 0.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) FOXP-CC PF16159.5 KPA41244.1 - 0.13 12.9 3.5 5.9 7.6 0.0 2.9 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KPA41244.1 - 0.84 10.6 14.1 1.8 9.6 0.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA41244.1 - 0.97 10.0 15.6 0.27 11.8 0.6 3.9 3 1 0 3 3 3 0 Zinc finger, C2H2 type p450 PF00067.22 KPA41245.1 - 1.6e-57 195.3 0.0 2.1e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tri3 PF07428.11 KPA41246.1 - 8.5e-166 551.9 0.0 1e-165 551.7 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 AATase PF07247.12 KPA41246.1 - 0.074 11.6 0.0 0.23 10.0 0.0 1.8 1 1 0 1 1 1 0 Alcohol acetyltransferase PMG PF05287.12 KPA41246.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 PMG protein MBOAT_2 PF13813.6 KPA41247.1 - 1.1e-20 73.6 3.0 1.1e-20 73.6 3.0 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family LIP PF03583.14 KPA41248.1 - 3.4e-60 203.8 0.1 4.7e-60 203.3 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase DUF4373 PF14297.6 KPA41248.1 - 0.14 12.9 0.0 0.31 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4373) Tyrosinase PF00264.20 KPA41249.1 - 3.7e-41 141.9 1.3 4.8e-41 141.5 1.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Lipase_GDSL_2 PF13472.6 KPA41250.1 - 4.7e-12 46.7 0.2 6.7e-12 46.2 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA41250.1 - 3.9e-07 30.3 0.3 5.9e-07 29.7 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SASA PF03629.18 KPA41250.1 - 2.3e-06 27.4 0.3 1.6e-05 24.7 0.3 1.9 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Glyco_hydro_17 PF00332.18 KPA41251.1 - 1.5e-18 67.5 1.8 2.9e-17 63.3 1.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 ThiS-like PF14453.6 KPA41251.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 ThiS-like ubiquitin Glyco_hydro_115 PF15979.5 KPA41252.1 - 1.3e-111 373.3 0.1 4.9e-85 286.0 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 115 GH115_C PF17829.1 KPA41252.1 - 4.3e-47 160.1 0.0 6.9e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Beta_helix PF13229.6 KPA41253.1 - 0.00089 19.1 26.1 0.0058 16.5 16.6 2.7 1 1 1 2 2 2 2 Right handed beta helix region Methyltransf_23 PF13489.6 KPA41254.1 - 2.8e-20 72.8 0.1 4.6e-20 72.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA41254.1 - 5.8e-13 48.9 0.0 1.1e-11 44.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA41254.1 - 3e-11 43.9 0.0 6.1e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA41254.1 - 1.2e-06 29.1 0.0 2.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA41254.1 - 8.3e-06 26.5 0.0 4.2e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA41254.1 - 9.5e-05 22.0 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KPA41254.1 - 0.0024 17.4 0.0 0.0084 15.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 KPA41254.1 - 0.005 16.2 0.0 0.011 15.1 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KPA41254.1 - 0.017 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KPA41254.1 - 0.042 13.1 0.0 0.079 12.2 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 KPA41254.1 - 0.047 13.8 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 KPA41254.1 - 0.056 12.8 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KPA41254.1 - 0.19 11.0 0.0 0.49 9.7 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NmrA PF05368.13 KPA41255.1 - 1.1e-36 126.6 0.0 2e-36 125.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA41255.1 - 5.1e-12 46.1 0.0 6.7e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA41255.1 - 1.5e-05 24.5 0.1 2.3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KPA41255.1 - 0.0019 17.7 0.1 0.0041 16.6 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 KPA41255.1 - 0.0034 17.9 0.3 0.0082 16.7 0.1 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KPA41255.1 - 0.0037 16.3 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KPA41255.1 - 0.015 14.9 0.2 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase LytR_C PF13399.6 KPA41255.1 - 0.019 16.0 0.4 0.87 10.6 0.0 2.4 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator TrkA_N PF02254.18 KPA41255.1 - 0.02 15.1 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KPA41255.1 - 0.022 15.0 0.1 0.038 14.2 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KPA41255.1 - 0.041 13.3 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KPA41255.1 - 0.053 14.0 0.1 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KPA41255.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KPA41255.1 - 0.17 11.3 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAAA-beta PF15508.6 KPA41256.1 - 6.2e-09 36.0 0.0 1.6e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase MCR_alpha PF02249.17 KPA41257.1 - 0.012 16.0 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Nucleotid_trans PF03407.16 KPA41258.1 - 5.7e-06 26.5 0.2 1.3e-05 25.3 0.1 1.6 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 KPA41258.1 - 0.00071 19.4 0.6 0.0047 16.7 0.6 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family p450 PF00067.22 KPA41259.1 - 2e-71 241.2 0.0 2.4e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CN_hydrolase PF00795.22 KPA41260.1 - 1.7e-40 139.0 0.0 2.1e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4794 PF16042.5 KPA41263.1 - 0.036 15.0 0.1 0.062 14.3 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4794) DUF4922 PF16269.5 KPA41263.1 - 0.17 11.6 2.0 1.2 8.9 2.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4922) Methyltransf_23 PF13489.6 KPA41267.1 - 3.5e-12 46.5 0.0 4.9e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA41267.1 - 1e-07 32.5 0.0 2.7e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA41267.1 - 0.00013 22.7 0.0 0.00042 21.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA41267.1 - 0.00013 22.5 0.0 0.0003 21.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA41267.1 - 0.00035 20.4 0.0 0.0024 17.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KPA41267.1 - 0.07 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain HET PF06985.11 KPA41268.1 - 2.4e-33 115.5 1.0 2.4e-33 115.5 1.0 2.2 3 0 0 3 3 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KPA41268.1 - 3.9e-31 107.5 0.9 9.7e-16 58.1 0.1 3.6 3 1 1 4 4 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA41268.1 - 4.2e-26 91.0 0.5 6.4e-10 39.4 0.0 5.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KPA41268.1 - 5.3e-21 74.1 1.9 0.00037 20.8 0.0 5.9 4 1 1 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KPA41268.1 - 8.5e-21 71.8 0.5 0.00018 21.7 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KPA41268.1 - 1.3e-19 70.0 1.3 5.2e-09 36.2 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KPA41268.1 - 1.3e-08 34.4 0.0 2.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 KPA41268.1 - 9.8e-06 26.1 0.1 5.7e-05 23.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KPA41268.1 - 0.00058 19.8 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KPA41268.1 - 0.0084 16.4 0.0 0.027 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KPA41268.1 - 0.045 14.2 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KPA41268.1 - 0.046 12.9 0.1 0.13 11.5 0.1 1.7 1 1 0 1 1 1 0 KAP family P-loop domain DUF3175 PF11373.8 KPA41268.1 - 0.071 13.3 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) DUF148 PF02520.17 KPA41268.1 - 0.18 11.9 1.7 42 4.3 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF148 NACHT_N PF17100.5 KPA41269.1 - 6.6e-25 88.3 0.5 1.4e-24 87.2 0.5 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 KPA41269.1 - 1.3e-08 35.3 0.9 0.033 15.1 0.1 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat NACHT PF05729.12 KPA41269.1 - 1.3e-07 31.7 2.0 2.9e-07 30.6 0.2 2.5 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KPA41269.1 - 1.5e-06 28.8 0.0 7.1e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain ANAPC4_WD40 PF12894.7 KPA41269.1 - 2.3e-05 24.6 0.5 1.2 9.4 0.1 4.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA41269.1 - 0.0033 16.1 2.3 0.038 12.6 0.1 2.3 1 1 1 2 2 2 1 Nucleoporin Nup120/160 APS_kinase PF01583.20 KPA41269.1 - 0.0041 17.0 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 KPA41269.1 - 0.0063 16.2 0.0 0.87 9.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KPA41269.1 - 0.024 14.9 0.0 0.072 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain eIF2A PF08662.11 KPA41269.1 - 0.059 13.2 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A NB-ARC PF00931.22 KPA41269.1 - 0.061 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 KPA41269.1 - 0.099 13.1 0.2 1.3 9.5 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF2433 PF10360.9 KPA41269.1 - 0.18 11.9 0.4 0.57 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) PD40 PF07676.12 KPA41269.1 - 0.22 11.5 0.6 0.81 9.7 0.3 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.16 KPA41270.1 - 4.3e-45 154.2 22.0 5.3e-45 153.9 22.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA41270.1 - 1.3e-16 60.6 7.6 1.3e-16 60.6 7.6 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KPA41270.1 - 2.3e-08 33.8 2.9 4.3e-08 32.9 2.9 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KPA41270.1 - 1.7e-06 26.7 1.6 2.4e-06 26.3 1.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.12 KPA41270.1 - 0.0018 16.9 0.0 0.0036 15.9 0.0 1.5 1 0 0 1 1 1 1 Ferroportin1 (FPN1) OATP PF03137.20 KPA41270.1 - 0.0082 14.5 2.6 0.011 14.1 2.0 1.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KPA41270.1 - 0.01 14.2 4.9 0.015 13.7 4.8 1.3 1 1 0 1 1 1 0 Transmembrane secretion effector BT1 PF03092.16 KPA41270.1 - 0.025 12.8 0.3 0.041 12.1 0.1 1.4 1 1 0 1 1 1 0 BT1 family TRIQK PF15168.6 KPA41270.1 - 0.22 11.5 2.2 0.29 11.0 0.7 1.9 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family p450 PF00067.22 KPA41271.1 - 1e-68 232.2 0.0 1.4e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.16 KPA41272.1 - 2.5e-06 27.0 0.1 3.3e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Zn_clus PF00172.18 KPA41275.1 - 0.00022 21.3 12.0 0.00037 20.5 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_1 PF00175.21 KPA41277.1 - 1.3e-10 41.9 0.0 2.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KPA41277.1 - 1.2e-08 35.5 0.1 2.2e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 KPA41277.1 - 5.4e-05 23.5 0.0 0.0002 21.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 KPA41277.1 - 0.00016 21.6 0.1 0.00028 20.8 0.1 1.4 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 KPA41277.1 - 0.0086 16.2 0.0 0.03 14.4 0.0 1.8 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Glycos_transf_1 PF00534.20 KPA41278.1 - 1.2e-23 83.5 0.0 2.8e-23 82.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KPA41278.1 - 5.4e-13 49.5 0.0 9.2e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KPA41278.1 - 0.017 15.5 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 APH PF01636.23 KPA41279.1 - 8.5e-06 25.9 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sod_Fe_C PF02777.18 KPA41280.1 - 2.5e-38 130.3 0.1 4.4e-38 129.6 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KPA41280.1 - 2.2e-30 105.0 1.5 3.7e-30 104.2 1.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sld5 PF05916.11 KPA41281.1 - 1.1e-18 67.7 0.0 1.7e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Uds1 PF15456.6 KPA41282.1 - 0.53 10.5 8.5 0.39 10.9 0.2 3.2 3 1 0 3 3 3 0 Up-regulated During Septation PRKCSH PF07915.13 KPA41283.1 - 2e-17 63.9 0.0 1.2e-16 61.5 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Cnn_1N PF07989.11 KPA41284.1 - 1.1e-07 31.9 7.5 1.1e-07 31.9 7.5 2.0 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 KPA41284.1 - 0.031 14.3 13.7 0.05 13.6 12.4 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 KPA41284.1 - 2.4 8.9 10.3 0.31 11.7 5.1 2.3 3 0 0 3 3 3 0 SlyX DPBB_1 PF03330.18 KPA41286.1 - 3.9e-06 27.1 0.1 4.8e-06 26.8 0.1 1.3 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KPA41286.1 - 0.028 14.3 0.1 0.036 13.9 0.1 1.2 1 0 0 1 1 1 0 Barwin family FAD_binding_4 PF01565.23 KPA41287.1 - 6.8e-21 74.5 1.4 3e-20 72.4 1.8 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KPA41287.1 - 3.2e-11 43.2 0.1 6.1e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Phage_holin_1 PF04531.13 KPA41288.1 - 1.3 9.6 5.1 41 4.8 3.6 2.6 2 0 0 2 2 2 0 Bacteriophage holin Arginase PF00491.21 KPA41289.1 - 7.8e-22 78.1 0.0 9.7e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF1118 PF06549.12 KPA41289.1 - 0.18 12.1 0.1 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) adh_short PF00106.25 KPA41290.1 - 2.5e-20 72.8 0.0 3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA41290.1 - 5e-13 49.1 0.0 6.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA41290.1 - 4.3e-06 26.7 0.0 6.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA41290.1 - 0.036 13.5 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA41290.1 - 0.24 10.8 0.0 0.3 10.5 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_dh_N PF08501.11 KPA41292.1 - 3.2e-21 75.4 0.0 7e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 KPA41292.1 - 7.7e-20 72.1 0.0 1.4e-19 71.3 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KPA41292.1 - 6.4e-13 49.1 0.1 1.4e-12 48.0 0.1 1.5 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 KPA41292.1 - 2.5e-12 46.3 0.2 5e-12 45.4 0.2 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KPA41292.1 - 8.1e-07 29.2 0.2 2.2e-06 27.8 0.2 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 KPA41292.1 - 0.0016 18.6 0.1 0.0037 17.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain ATP-synt_F PF01990.17 KPA41292.1 - 0.0042 17.4 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 1 ATP synthase (F/14-kDa) subunit F420_oxidored PF03807.17 KPA41292.1 - 0.02 15.5 1.2 0.21 12.2 0.0 2.8 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 KPA41292.1 - 0.021 14.3 0.1 0.045 13.2 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Zeta_toxin PF06414.12 KPA41292.1 - 0.028 13.7 0.1 0.048 12.9 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KPA41292.1 - 0.031 14.8 0.0 0.075 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter OCD_Mu_crystall PF02423.15 KPA41292.1 - 0.04 12.9 0.3 0.092 11.7 0.0 1.6 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Sacchrp_dh_NADP PF03435.18 KPA41292.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AAA_16 PF13191.6 KPA41292.1 - 0.061 13.7 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KPA41292.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_8 PF12780.7 KPA41292.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Zn_clus PF00172.18 KPA41293.1 - 2.2e-07 30.9 10.9 4.7e-07 29.8 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA41293.1 - 0.0004 19.5 0.1 0.0025 16.9 0.0 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KPA41294.1 - 6.5e-135 450.5 24.6 7.5e-135 450.3 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA41294.1 - 6.2e-26 91.1 29.6 6.2e-26 91.1 29.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Beta-lactamase PF00144.24 KPA41295.1 - 5.3e-30 104.8 0.0 8.6e-30 104.1 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 KPA41296.1 - 7.3e-32 110.6 29.3 7.3e-32 110.6 29.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA41296.1 - 8.8e-11 41.3 7.5 8.8e-11 41.3 7.5 3.3 3 1 1 4 4 4 2 Sugar (and other) transporter Shikimate_dh_N PF08501.11 KPA41297.1 - 1.4e-19 70.1 0.0 2.9e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KPA41297.1 - 3.1e-05 23.7 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KPA41297.1 - 0.013 15.5 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1174 PF06671.11 KPA41297.1 - 0.31 10.8 3.6 0.71 9.6 3.6 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1174) AP_endonuc_2 PF01261.24 KPA41298.1 - 5e-32 111.0 0.0 6.8e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DHquinase_II PF01220.19 KPA41299.1 - 1.1e-62 209.8 0.3 1.2e-62 209.6 0.3 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Inositol_P PF00459.25 KPA41300.1 - 1.8e-81 273.6 0.0 2.1e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MutS_V PF00488.21 KPA41301.1 - 5.8e-61 205.8 0.5 1.1e-60 204.8 0.5 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KPA41301.1 - 2e-30 106.5 3.8 2e-30 106.5 3.8 2.3 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KPA41301.1 - 1.1e-05 25.7 1.2 8.6e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 KPA41301.1 - 0.00042 20.6 0.1 0.0012 19.2 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 KPA41301.1 - 0.0051 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain KdpD PF02702.17 KPA41301.1 - 0.086 12.3 0.2 0.23 10.9 0.2 1.7 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Med15 PF09606.10 KPA41302.1 - 2.8e-05 23.1 47.4 3.1e-05 22.9 47.4 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal FAR1 PF03101.15 KPA41302.1 - 0.0021 18.7 0.9 0.0021 18.7 0.9 2.9 2 1 0 2 2 2 1 FAR1 DNA-binding domain Miga PF10265.9 KPA41302.1 - 0.36 9.8 12.7 0.49 9.3 12.7 1.1 1 0 0 1 1 1 0 Mitoguardin MMR1 PF08505.10 KPA41302.1 - 0.4 10.9 20.4 0.62 10.3 20.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 KPA41302.1 - 0.62 10.0 42.1 0.92 9.4 42.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 KPA41302.1 - 1.7 8.4 16.4 3.3 7.5 16.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 KPA41302.1 - 2 5.4 19.8 2.6 5.0 19.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDK5_activator PF03261.15 KPA41302.1 - 7 6.1 17.1 9.2 5.7 17.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PAT1 PF09770.9 KPA41302.1 - 7.7 4.6 37.2 9.4 4.4 37.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.32 KPA41303.1 - 2e-56 186.7 34.9 3.3e-10 40.4 0.2 9.3 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA41303.1 - 4.4e-21 75.0 6.5 0.0029 17.9 0.0 6.5 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA41303.1 - 3.3e-08 32.9 0.1 0.2 10.5 0.0 5.1 3 3 3 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KPA41303.1 - 2e-06 27.8 0.3 0.00017 21.5 0.0 2.9 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KPA41303.1 - 2.1e-06 26.7 2.2 0.1 11.2 0.1 4.6 4 2 0 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 KPA41303.1 - 0.0035 17.3 0.2 17 5.5 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat NLE PF08154.12 KPA41303.1 - 0.0042 17.6 0.0 0.0092 16.5 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.11 KPA41303.1 - 0.013 15.7 0.0 0.17 12.1 0.0 2.6 2 1 1 3 3 3 0 Siderophore-interacting FAD-binding domain WD40_like PF17005.5 KPA41303.1 - 0.017 14.5 0.0 18 4.6 0.0 3.5 4 0 0 4 4 4 0 WD40-like domain Glyco_transf_4 PF13439.6 KPA41303.1 - 0.049 13.6 0.2 0.087 12.8 0.2 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_transf_20 PF00982.21 KPA41304.1 - 6.3e-164 546.1 0.1 9.4e-164 545.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KPA41304.1 - 4.3e-42 143.9 0.0 7.1e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Aminotran_4 PF01063.19 KPA41304.1 - 1.3e-24 87.3 0.0 2.3e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV Glyco_transf_5 PF08323.11 KPA41304.1 - 0.12 12.1 0.6 0.26 10.9 0.6 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Catalase PF00199.19 KPA41306.1 - 5.5e-175 582.0 0.2 6.8e-175 581.7 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KPA41306.1 - 3.5e-14 52.7 0.0 9.2e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Amidoligase_2 PF12224.8 KPA41307.1 - 6e-13 49.0 0.0 4.3e-08 33.1 0.0 3.1 1 1 1 2 2 2 2 Putative amidoligase enzyme Acetyltransf_10 PF13673.7 KPA41309.1 - 0.00056 19.8 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA41309.1 - 0.0012 19.2 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA41309.1 - 0.054 13.7 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 KPA41309.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Ank_2 PF12796.7 KPA41310.1 - 6.6e-34 116.4 17.2 1.5e-06 28.7 0.0 14.2 10 5 3 14 14 14 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA41310.1 - 1.4e-21 76.5 9.1 0.0087 16.6 0.0 14.6 16 0 0 16 16 16 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA41310.1 - 4.7e-16 57.3 12.0 0.088 13.4 0.0 15.0 17 0 0 17 17 17 4 Ankyrin repeat Ank_5 PF13857.6 KPA41310.1 - 2.8e-15 56.2 12.8 2.4e-07 30.9 0.0 10.7 11 2 1 12 12 12 3 Ankyrin repeats (many copies) Ank PF00023.30 KPA41310.1 - 3.8e-12 46.1 19.4 0.00015 22.1 0.0 13.9 15 2 1 16 16 16 2 Ankyrin repeat ADH_zinc_N PF00107.26 KPA41311.1 - 1.3e-26 93.1 0.4 1.3e-26 93.1 0.4 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA41311.1 - 6.9e-19 69.2 0.1 1.3e-18 68.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA41311.1 - 2.3e-08 33.9 0.0 1.6e-07 31.1 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KPA41311.1 - 0.00089 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 KPA41311.1 - 0.017 14.6 0.3 0.035 13.6 0.3 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 KPA41312.1 - 5e-40 137.5 0.0 6.9e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA41312.1 - 4.3e-38 131.5 0.0 7.7e-38 130.7 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPA41312.1 - 9.6e-12 44.5 0.0 4.1e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KPA41312.1 - 8.9e-07 28.6 0.1 2.2e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KPA41312.1 - 1.4e-05 24.4 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KPA41312.1 - 1.6e-05 24.2 0.0 0.0012 18.1 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KPA41312.1 - 5.2e-05 23.2 0.0 0.00047 20.1 0.0 2.0 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KPA41312.1 - 8.9e-05 22.4 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KPA41312.1 - 0.0012 18.0 0.0 1 8.5 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KPA41312.1 - 0.02 14.5 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 KPA41312.1 - 0.024 14.2 0.2 0.04 13.5 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.6 KPA41312.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Sad1_UNC PF07738.13 KPA41313.1 - 4.4e-11 42.9 0.0 1.7e-05 24.8 0.0 2.3 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal YqeY PF09424.10 KPA41313.1 - 0.48 10.5 3.0 6.1 6.9 3.0 2.3 1 1 0 1 1 1 0 Yqey-like protein DUF4200 PF13863.6 KPA41313.1 - 0.61 10.5 7.4 0.47 10.8 4.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DEAD PF00270.29 KPA41314.1 - 8.8e-48 162.4 0.0 1.8e-47 161.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA41314.1 - 6.8e-25 87.6 0.0 3.4e-24 85.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KPA41314.1 - 2.4e-23 82.1 0.0 2e-22 79.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KPA41314.1 - 1.3e-07 31.7 0.1 5.6e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NUC153 PF08159.12 KPA41315.1 - 3.5e-15 55.5 0.5 3.5e-15 55.5 0.5 3.6 3 0 0 3 3 3 2 NUC153 domain Methyltransf_23 PF13489.6 KPA41316.1 - 3.7e-18 65.9 0.0 4.5e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA41316.1 - 1.7e-09 38.3 0.0 4.9e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA41316.1 - 8.2e-08 32.8 0.0 1.3e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA41316.1 - 9.8e-08 31.9 0.0 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KPA41316.1 - 1e-06 29.4 0.0 8.4e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KPA41316.1 - 0.0012 19.0 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KPA41316.1 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KPA41316.1 - 0.0036 16.9 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KPA41316.1 - 0.0069 15.8 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KPA41316.1 - 0.014 15.2 0.0 0.021 14.5 0.0 1.4 1 1 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KPA41316.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF4267 PF14087.6 KPA41318.1 - 0.0014 18.7 0.2 0.002 18.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) FMO-like PF00743.19 KPA41319.1 - 5.2e-31 107.7 0.0 1.4e-15 56.8 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPA41319.1 - 2.1e-12 47.0 1.2 7e-10 38.7 0.1 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA41319.1 - 5.6e-09 35.6 0.4 5.2e-07 29.1 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPA41319.1 - 5.1e-08 32.5 0.1 3.5e-07 29.8 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA41319.1 - 1.3e-06 28.5 2.7 2.2e-05 24.5 0.3 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPA41319.1 - 0.00015 21.9 0.0 0.00052 20.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA41319.1 - 0.0027 17.4 2.8 1.1 8.8 0.3 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KPA41319.1 - 0.018 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Catalase_C PF18011.1 KPA41319.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases Fungal_trans_2 PF11951.8 KPA41320.1 - 6.9e-26 91.0 3.6 7.2e-25 87.6 3.6 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41320.1 - 1.1e-09 38.2 9.1 2.3e-09 37.2 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EutQ PF06249.12 KPA41321.1 - 2.1e-10 40.5 0.0 2.5e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 KPA41321.1 - 4.2e-08 32.8 0.0 5.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KPA41321.1 - 0.00012 21.7 0.0 0.00022 20.9 0.0 1.5 1 1 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KPA41321.1 - 0.0016 18.2 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 Cupin Pirin PF02678.16 KPA41321.1 - 0.017 15.1 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 Pirin AraC_binding PF02311.19 KPA41321.1 - 0.027 14.4 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF3445 PF11927.8 KPA41322.1 - 3.1e-77 259.2 0.0 4e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3445 PF11927.8 KPA41323.1 - 1.1e-72 244.4 0.0 1.4e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PAS_8 PF13188.7 KPA41323.1 - 0.14 12.3 0.0 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 PAS domain DAO PF01266.24 KPA41325.1 - 3.2e-43 148.7 0.0 3.7e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA41325.1 - 7.2e-06 26.1 0.0 2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA41325.1 - 0.00018 20.9 0.1 0.01 15.1 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA41325.1 - 0.0044 17.6 0.0 0.015 15.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA41325.1 - 0.005 16.1 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 KPA41325.1 - 0.0051 16.9 0.0 0.015 15.4 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KPA41325.1 - 0.0061 15.7 0.3 0.11 11.5 0.1 2.3 3 0 0 3 3 3 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 KPA41325.1 - 0.032 14.5 0.3 0.26 11.6 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KPA41325.1 - 0.036 14.3 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 KPA41325.1 - 0.042 14.3 0.0 0.075 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KPA41325.1 - 0.048 13.7 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 KPA41325.1 - 0.048 13.3 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KPA41325.1 - 0.065 12.3 0.4 3.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KPA41325.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KPA41326.1 - 0.022 13.8 0.0 0.046 12.7 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain Helo_like_N PF17111.5 KPA41330.1 - 6.2e-07 29.0 1.9 1.1e-06 28.2 1.9 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Prominin PF05478.11 KPA41330.1 - 0.0031 15.6 2.2 0.019 13.0 1.4 2.0 1 1 1 2 2 2 2 Prominin BLOC1_2 PF10046.9 KPA41330.1 - 0.079 13.3 1.6 2.5 8.5 0.4 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Abhydrolase_1 PF00561.20 KPA41332.1 - 4.1e-12 46.3 0.3 8.4e-12 45.3 0.3 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA41332.1 - 5.1e-10 40.3 0.0 6.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA41332.1 - 7.7e-05 22.1 0.1 0.00011 21.6 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KPA41332.1 - 0.00054 20.1 0.0 0.00071 19.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KPA41332.1 - 0.00097 18.8 0.1 0.0017 18.1 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Palm_thioest PF02089.15 KPA41332.1 - 0.0024 17.8 0.0 0.003 17.4 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase UPF0227 PF05728.12 KPA41332.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 KPA41332.1 - 0.018 14.7 0.6 4 7.1 0.0 2.3 1 1 1 2 2 2 0 PGAP1-like protein Abhydrolase_2 PF02230.16 KPA41332.1 - 0.02 14.7 1.3 1.6 8.5 0.2 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF676 PF05057.14 KPA41332.1 - 0.021 14.3 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) HicA_toxin PF07927.12 KPA41332.1 - 0.096 12.7 0.2 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, Abhydrolase_5 PF12695.7 KPA41332.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.24 KPA41333.1 - 1.6e-89 300.8 11.0 1.9e-89 300.6 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA41333.1 - 5.6e-29 101.2 29.0 4.1e-28 98.3 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA41333.1 - 9.8e-06 24.3 2.9 9.8e-06 24.3 2.9 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Asp_Glu_race PF01177.22 KPA41334.1 - 9.7e-05 22.3 0.0 0.00019 21.3 0.0 1.4 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Actin PF00022.19 KPA41335.1 - 3.7e-112 374.9 0.0 2.2e-111 372.4 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KPA41335.1 - 0.013 14.4 0.0 0.092 11.5 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein Actin_micro PF17003.5 KPA41335.1 - 0.022 13.9 0.6 0.21 10.7 0.2 2.5 3 0 0 3 3 3 0 Putative actin-like family Pkinase PF00069.25 KPA41336.1 - 1.8e-63 214.4 0.0 2.3e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA41336.1 - 3.7e-30 105.1 0.0 8.4e-30 103.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA41336.1 - 0.05 12.9 0.0 0.089 12.1 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KPA41336.1 - 0.073 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KPA41336.1 - 0.19 11.7 0.0 0.59 10.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.21 KPA41337.1 - 9.7e-76 253.1 0.2 1.1e-75 252.9 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KPA41337.1 - 1.8e-14 54.0 0.0 2.6e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KPA41337.1 - 4.3e-14 52.4 1.7 3.2e-10 39.7 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KPA41337.1 - 2.2e-13 50.1 0.0 2.5e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KPA41337.1 - 2.6e-12 46.6 0.1 3.3e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KPA41337.1 - 3.7e-12 46.0 0.0 4.7e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPA41337.1 - 0.00031 20.8 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KPA41337.1 - 0.023 14.0 0.3 0.068 12.5 0.3 1.8 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Methyltrn_RNA_3 PF02598.17 KPA41337.1 - 0.028 13.9 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase CRISPR_Cas2 PF09827.9 KPA41337.1 - 0.062 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 SpoOE-like PF09388.10 KPA41337.1 - 0.064 13.2 1.5 0.11 12.4 1.5 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein DUF1325 PF07039.11 KPA41338.1 - 1.2e-36 125.8 0.1 2e-36 125.0 0.1 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Atrophin-1 PF03154.15 KPA41338.1 - 0.00012 20.6 7.4 0.00012 20.6 7.4 2.1 2 0 0 2 2 2 1 Atrophin-1 family PRP38_assoc PF12871.7 KPA41338.1 - 0.0012 19.4 23.9 0.0012 19.4 23.9 3.8 3 1 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Pol_alpha_B_N PF08418.10 KPA41338.1 - 5.7 6.8 21.5 0.47 10.4 9.3 2.5 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal PMI_typeI PF01238.21 KPA41339.1 - 8.7e-139 462.9 0.0 1e-138 462.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Pro_isomerase PF00160.21 KPA41341.1 - 5.4e-35 121.0 0.0 8.4e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KPA41341.1 - 6.1e-15 54.8 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FliT PF05400.13 KPA41342.1 - 0.0053 17.5 1.1 0.037 14.8 0.4 2.2 2 0 0 2 2 2 1 Flagellar protein FliT PNISR PF15996.5 KPA41342.1 - 0.018 15.3 0.3 0.026 14.8 0.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Methyltransf_16 PF10294.9 KPA41343.1 - 3e-19 69.4 0.0 4.9e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KPA41343.1 - 0.00034 20.1 0.0 0.0061 16.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KPA41343.1 - 0.00062 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KPA41343.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KPA41343.1 - 0.0026 18.4 0.1 0.012 16.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 KPA41343.1 - 0.0045 16.8 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein DUF938 PF06080.12 KPA41343.1 - 0.0063 16.3 0.0 0.017 14.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Methyltransf_31 PF13847.6 KPA41343.1 - 0.019 14.8 0.1 0.037 13.8 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KPA41343.1 - 0.026 14.3 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KPA41343.1 - 0.036 14.8 0.0 0.084 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KPA41343.1 - 0.086 11.9 0.0 0.19 10.8 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase RrnaAD PF00398.20 KPA41343.1 - 0.099 11.7 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ribosomal_S24e PF01282.19 KPA41344.1 - 4e-35 119.6 0.0 7e-35 118.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e GTP_cyclohydro2 PF00925.20 KPA41346.1 - 1.7e-60 203.3 0.0 2.2e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II Cerato-platanin PF07249.12 KPA41347.1 - 6.9e-05 23.0 1.1 9.1e-05 22.6 0.2 1.6 2 0 0 2 2 2 1 Cerato-platanin Plasmod_Pvs28 PF06247.11 KPA41347.1 - 0.12 12.7 0.4 0.12 12.7 0.4 2.3 2 0 0 2 2 2 0 Pvs28 EGF domain RPA43_OB PF17875.1 KPA41348.1 - 4.2e-34 117.8 0.1 4.2e-34 117.8 0.1 4.6 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I Aa_trans PF01490.18 KPA41349.1 - 6.1e-30 104.2 38.8 7e-30 104.0 38.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NDUF_B7 PF05676.13 KPA41350.1 - 1.7e-30 104.5 5.8 2e-30 104.3 5.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KPA41350.1 - 0.0017 18.3 1.8 0.002 18.1 1.6 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like RRM_1 PF00076.22 KPA41351.1 - 4.6e-15 55.2 0.0 7e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPA41351.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KPA41351.1 - 0.054 13.5 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Glyco_hydro_3_C PF01915.22 KPA41352.1 - 2.5e-63 213.7 0.0 6.4e-63 212.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPA41352.1 - 2.9e-51 174.8 0.0 6.8e-51 173.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 KPA41352.1 - 1.4e-22 80.1 0.0 2.4e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 KPA41352.1 - 2e-21 75.8 0.1 4.2e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain SurA_N_3 PF13624.6 KPA41352.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 SurA N-terminal domain ERO1 PF04137.15 KPA41354.1 - 7.7e-135 449.6 0.0 7.7e-135 449.6 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) CKS PF01111.19 KPA41355.1 - 1.6e-34 118.0 1.1 1.9e-34 117.7 1.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit HVSL PF09749.9 KPA41356.1 - 4.4e-81 271.9 0.0 5.2e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.11 KPA41357.1 - 5.6e-09 36.9 0.0 5.6e-09 36.9 0.0 2.6 2 1 1 3 3 3 1 Pal1 cell morphology protein CPSF_A PF03178.15 KPA41358.1 - 3.3e-76 256.7 0.0 5.3e-75 252.7 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KPA41358.1 - 6.1e-17 61.4 0.0 1.2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.16 KPA41359.1 - 1.5e-19 70.3 9.6 1.6e-18 67.0 2.0 2.7 2 1 1 3 3 3 2 LMBR1-like membrane protein zf-B_box PF00643.24 KPA41360.1 - 0.095 12.9 2.3 0.14 12.3 2.3 1.2 1 0 0 1 1 1 0 B-box zinc finger zf-MYND PF01753.18 KPA41360.1 - 0.18 11.9 5.4 0.31 11.2 5.4 1.3 1 0 0 1 1 1 0 MYND finger Mannosyl_trans3 PF11051.8 KPA41361.1 - 1.5e-40 139.3 0.0 5.7e-40 137.4 0.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KPA41361.1 - 0.064 12.8 0.1 0.15 11.5 0.1 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KPA41361.1 - 0.085 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase NAD_binding_1 PF00175.21 KPA41362.1 - 1.7e-25 89.8 0.0 2.5e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KPA41362.1 - 2.4e-17 63.1 0.0 4.6e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KPA41362.1 - 6.2e-05 23.2 0.0 0.0078 16.3 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Hydantoinase_B PF02538.14 KPA41363.1 - 1.3e-209 696.9 0.8 1.8e-209 696.4 0.8 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KPA41363.1 - 4.5e-91 305.1 0.0 1.1e-90 303.9 0.0 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KPA41363.1 - 1.4e-58 197.5 0.2 5e-57 192.5 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Fungal_trans PF04082.18 KPA41364.1 - 4.9e-23 81.5 0.0 1.1e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41364.1 - 9e-06 25.7 11.6 1.6e-05 24.9 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPA41365.1 - 1.6e-38 132.6 20.8 1.9e-37 129.0 22.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KPA41365.1 - 0.071 12.9 0.3 0.38 10.5 0.1 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1772 PF08592.11 KPA41365.1 - 0.78 10.1 6.7 14 6.0 1.9 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) DUF2070 PF09843.9 KPA41365.1 - 7.6 4.7 9.4 0.076 11.3 0.6 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) MAGUK_N_PEST PF10608.9 KPA41366.1 - 0.033 14.6 1.7 0.037 14.5 1.7 1.2 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK HeLo PF14479.6 KPA41367.1 - 8.4e-35 120.5 0.2 1.4e-34 119.7 0.2 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.12 KPA41367.1 - 5.4e-09 36.2 0.2 7.8e-08 32.4 0.2 3.3 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KPA41367.1 - 1.9e-05 25.1 0.0 5.5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA41367.1 - 0.00036 20.8 0.0 0.0011 19.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF2383 PF09537.10 KPA41367.1 - 0.0076 16.6 0.0 0.03 14.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) ABC_tran PF00005.27 KPA41367.1 - 0.0087 16.6 0.1 0.051 14.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ATPase_2 PF01637.18 KPA41367.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KPA41367.1 - 0.024 13.9 0.1 1.6 7.9 0.1 2.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.6 KPA41367.1 - 0.038 13.7 0.1 0.078 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KPA41367.1 - 0.11 13.1 0.0 0.54 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KPA41367.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 KPA41367.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF4345 PF14248.6 KPA41368.1 - 4.9e-25 87.7 6.0 5.8e-25 87.5 6.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) DUF1129 PF06570.11 KPA41368.1 - 0.072 12.6 0.1 0.11 11.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) adh_short PF00106.25 KPA41370.1 - 4.7e-35 120.8 0.0 6.7e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA41370.1 - 3.3e-26 92.3 0.1 4.3e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA41370.1 - 4.5e-06 26.7 0.0 7.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KPA41370.1 - 2.4e-05 23.9 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KPA41370.1 - 0.00095 19.1 0.1 0.0019 18.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 KPA41370.1 - 0.073 13.1 0.2 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PAN_1 PF00024.26 KPA41372.1 - 0.022 14.7 0.5 0.034 14.1 0.5 1.4 1 0 0 1 1 1 0 PAN domain Kinesin PF00225.23 KPA41373.1 - 7e-116 386.8 0.1 1.1e-115 386.2 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPA41373.1 - 6.1e-27 94.4 0.0 1.4e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 KPA41373.1 - 0.0041 17.4 2.0 0.012 15.9 2.0 1.8 1 0 0 1 1 1 1 Herpesvirus UL14-like protein MgrB PF13998.6 KPA41373.1 - 0.12 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 MgrB protein Fungal_trans PF04082.18 KPA41374.1 - 2.6e-09 36.5 0.0 4.4e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41374.1 - 3.4e-07 30.3 7.5 3.4e-07 30.3 7.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KPA41374.1 - 2.1e-05 24.7 3.1 0.035 14.6 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA41374.1 - 0.00021 21.9 10.1 0.02 15.7 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Fanconi_A_N PF15865.5 KPA41374.1 - 0.048 13.0 0.1 0.085 12.2 0.1 1.3 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus CGI-121 PF08617.10 KPA41375.1 - 5.4e-54 182.7 0.2 6.2e-54 182.5 0.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Ubiq-Cytc-red_N PF09165.10 KPA41375.1 - 0.058 14.3 0.3 0.16 12.9 0.3 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Pro_dh PF01619.18 KPA41376.1 - 1.7e-73 247.7 0.0 2.1e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Tim17 PF02466.19 KPA41377.1 - 0.00018 21.8 3.3 0.00025 21.4 3.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CYSTM PF12734.7 KPA41381.1 - 0.00034 20.9 63.5 0.0057 17.0 42.3 4.1 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance PTPLA PF04387.14 KPA41382.1 - 4.9e-44 150.0 6.7 4.9e-44 150.0 6.7 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Amino_oxidase PF01593.24 KPA41383.1 - 5e-50 171.1 0.0 6.3e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA41383.1 - 1.7e-11 44.2 0.4 3.5e-11 43.2 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPA41383.1 - 1.1e-08 34.9 0.0 4.6e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPA41383.1 - 3.2e-08 33.1 0.1 5.2e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KPA41383.1 - 1.4e-07 31.5 2.2 7e-07 29.1 2.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA41383.1 - 5.6e-07 29.1 0.0 2.6e-06 26.9 0.0 2.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPA41383.1 - 1e-06 28.1 0.7 2.2e-06 27.0 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KPA41383.1 - 1.5e-06 27.6 0.0 2.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KPA41383.1 - 1.4e-05 24.0 0.1 0.00015 20.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KPA41383.1 - 0.00013 21.3 0.4 0.071 12.3 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA41383.1 - 0.00056 20.4 0.2 0.0038 17.8 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA41383.1 - 0.00089 18.4 0.1 0.0016 17.6 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KPA41383.1 - 0.0015 17.8 0.2 0.0033 16.7 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KPA41383.1 - 0.07 12.4 0.2 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain INSIG PF07281.12 KPA41384.1 - 0.029 14.0 1.5 0.036 13.7 1.5 1.2 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) CDP-OH_P_tran_2 PF08009.11 KPA41384.1 - 2.8 7.9 9.3 0.41 10.6 4.3 2.3 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 LON_substr_bdg PF02190.16 KPA41385.1 - 2.8e-26 92.7 0.0 4.4e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KPA41385.1 - 5.6e-15 54.9 19.6 7.9e-12 44.8 10.1 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPA41385.1 - 1.3e-11 44.4 18.5 2.7e-06 27.4 7.6 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KPA41385.1 - 2e-11 43.7 21.0 1.5e-08 34.6 5.2 3.3 2 1 1 3 3 3 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KPA41385.1 - 7.8e-11 41.7 16.6 5.2e-09 35.8 7.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA41385.1 - 1.3e-10 41.4 24.3 1.3e-07 31.8 10.5 2.7 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 KPA41385.1 - 1.8e-10 40.5 19.5 1.3e-07 31.3 9.8 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPA41385.1 - 1.4e-08 34.5 20.9 1.3e-06 28.2 9.7 2.5 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 KPA41385.1 - 5.1e-05 23.1 19.3 0.00017 21.4 7.9 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KPA41385.1 - 7.8e-05 22.4 2.9 7.8e-05 22.4 2.9 3.2 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain U-box PF04564.15 KPA41385.1 - 0.00013 22.1 0.4 0.0059 16.8 0.0 2.8 3 0 0 3 3 2 1 U-box domain zf-P11 PF03854.14 KPA41385.1 - 0.00022 20.8 6.1 0.00022 20.8 6.1 2.7 3 0 0 3 3 3 1 P-11 zinc finger zf-rbx1 PF12678.7 KPA41385.1 - 0.003 17.8 5.4 0.003 17.8 5.4 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KPA41385.1 - 0.0055 16.8 5.5 0.0055 16.8 5.5 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 zinc_ribbon_2 PF13240.6 KPA41385.1 - 0.036 13.8 0.8 0.082 12.7 0.1 2.1 2 0 0 2 2 1 0 zinc-ribbon domain DZR PF12773.7 KPA41385.1 - 0.066 13.2 0.3 0.066 13.2 0.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-Nse PF11789.8 KPA41385.1 - 2.4 8.0 12.2 0.064 13.1 4.2 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_15 PF17032.5 KPA41385.1 - 8.7 7.2 8.3 1.9 9.3 4.1 2.1 2 0 0 2 2 2 0 zinc-ribbon family NUDIX PF00293.28 KPA41387.1 - 2e-15 57.0 0.0 4e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KPA41387.1 - 3e-10 40.6 0.0 1.3e-09 38.6 0.0 2.1 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KPA41387.1 - 8.3e-08 31.8 0.9 1.6e-07 30.9 0.9 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain PQ-loop PF04193.14 KPA41388.1 - 3e-19 68.5 0.8 3e-19 68.5 0.8 1.9 2 0 0 2 2 2 1 PQ loop repeat MtN3_slv PF03083.16 KPA41388.1 - 0.071 13.1 0.2 0.18 11.9 0.2 1.6 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Tim17 PF02466.19 KPA41389.1 - 7.3e-27 93.9 4.9 1.3e-26 93.2 3.5 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family CoaE PF01121.20 KPA41393.1 - 7.7e-42 143.0 0.0 2.7e-41 141.2 0.0 1.7 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 KPA41393.1 - 0.0041 17.3 0.0 0.047 13.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KPA41393.1 - 0.015 15.8 0.4 0.081 13.5 0.2 2.4 1 1 1 2 2 2 0 AAA domain FixP_N PF14715.6 KPA41393.1 - 0.019 14.7 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP 2TM PF13239.6 KPA41393.1 - 0.02 15.2 1.1 0.038 14.3 1.1 1.5 1 0 0 1 1 1 0 2TM domain SKI PF01202.22 KPA41393.1 - 0.12 12.5 0.1 2.5 8.2 0.0 2.6 2 1 1 3 3 3 0 Shikimate kinase BEX PF04538.12 KPA41394.1 - 0.37 11.4 3.9 1.4 9.5 3.9 2.0 1 1 0 1 1 1 0 Brain expressed X-linked like family AA_permease PF00324.21 KPA41395.1 - 1.1e-133 446.4 42.7 1.3e-133 446.1 42.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA41395.1 - 1.3e-36 126.3 42.2 2e-36 125.8 42.0 1.3 1 1 0 1 1 1 1 Amino acid permease HEAT_2 PF13646.6 KPA41396.1 - 0.018 15.4 4.9 2.4 8.6 0.1 4.6 5 1 0 5 5 5 0 HEAT repeats Cnd1 PF12717.7 KPA41396.1 - 0.052 13.6 7.4 0.053 13.6 1.4 3.8 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KPA41396.1 - 0.075 13.2 0.0 1.9 8.7 0.0 3.3 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TagF_N PF09867.9 KPA41396.1 - 0.22 11.5 0.9 0.61 10.1 0.2 2.2 2 0 0 2 2 2 0 TagF N-terminal domain, Type VI secretion system-associated DUF1749 PF08538.10 KPA41397.1 - 7.3e-70 235.4 0.0 9e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KPA41397.1 - 2.4e-06 28.3 0.0 3.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA41397.1 - 7.2e-06 25.4 0.0 0.049 12.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA41397.1 - 4e-05 23.4 0.0 0.0013 18.4 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KPA41397.1 - 0.12 12.1 0.6 5.7 6.7 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase ABC_membrane PF00664.23 KPA41398.1 - 3.5e-86 289.2 37.8 6.8e-48 163.7 8.2 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA41398.1 - 8.8e-50 168.8 0.0 2.1e-30 106.0 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPA41398.1 - 1.6e-09 37.5 4.1 0.0048 16.4 0.1 4.2 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain MTABC_N PF16185.5 KPA41398.1 - 1.2e-05 25.0 6.9 1.2e-05 25.0 6.9 2.0 2 0 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region MMR_HSR1 PF01926.23 KPA41398.1 - 1.5e-05 25.1 0.3 0.23 11.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA41398.1 - 0.00034 20.6 0.0 0.46 10.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KPA41398.1 - 0.0025 17.9 1.7 0.14 12.2 0.2 2.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KPA41398.1 - 0.0049 16.6 0.6 1.6 8.5 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain UPF0093 PF03653.13 KPA41398.1 - 0.029 14.6 0.5 0.029 14.6 0.5 2.1 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0093) AAA_16 PF13191.6 KPA41398.1 - 0.032 14.6 3.8 0.14 12.6 0.2 2.9 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 KPA41398.1 - 0.034 14.5 0.1 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 KPA41398.1 - 0.052 13.3 0.5 11 5.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane_2 PF06472.15 KPA41398.1 - 0.072 12.5 0.1 0.072 12.5 0.1 2.9 3 0 0 3 3 3 0 ABC transporter transmembrane region 2 AAA_30 PF13604.6 KPA41398.1 - 0.1 12.3 1.8 1.3 8.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KPA41398.1 - 0.13 12.5 0.5 47 4.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KPA41398.1 - 0.14 12.2 4.9 0.68 10.0 0.2 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AIG1 PF04548.16 KPA41398.1 - 0.15 11.3 0.7 4 6.7 0.0 2.4 2 0 0 2 2 2 0 AIG1 family DUP PF00674.18 KPA41398.1 - 0.15 12.2 1.0 0.74 10.0 1.0 2.2 1 0 0 1 1 1 0 DUP family NACHT PF05729.12 KPA41398.1 - 0.2 11.6 1.2 0.72 9.8 0.1 2.4 3 0 0 3 3 2 0 NACHT domain AAA_15 PF13175.6 KPA41398.1 - 0.54 9.9 2.9 10 5.7 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain Roc PF08477.13 KPA41398.1 - 2.4 8.4 4.5 45 4.3 0.0 3.8 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2841 PF11001.8 KPA41399.1 - 7.2e-41 139.1 2.4 1e-40 138.6 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) HLH PF00010.26 KPA41400.1 - 8.3e-13 48.1 0.3 1.7e-12 47.1 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GIT1_C PF12205.8 KPA41400.1 - 0.013 15.6 1.5 0.14 12.3 1.5 2.2 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term CLTH PF10607.9 KPA41401.1 - 4.2e-34 117.6 0.0 7.4e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KPA41401.1 - 3.7e-05 23.5 0.2 9.7e-05 22.2 0.2 1.8 1 0 0 1 1 1 1 LisH CAF1 PF04857.20 KPA41402.1 - 1.1e-21 77.4 0.0 7e-10 38.6 0.1 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 KPA41402.1 - 0.21 12.2 0.0 0.47 11.1 0.0 1.6 1 0 0 1 1 1 0 RFX DNA-binding domain NDUF_B12 PF08122.12 KPA41403.1 - 8e-26 89.8 0.9 1.1e-25 89.4 0.9 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Spc7 PF08317.11 KPA41404.1 - 0.02 13.8 6.9 0.032 13.1 6.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HTH_Tnp_1 PF01527.20 KPA41404.1 - 0.054 13.8 0.4 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 Transposase SlyX PF04102.12 KPA41404.1 - 0.82 10.3 4.5 2.8 8.6 3.4 2.3 2 0 0 2 2 2 0 SlyX ThiF PF00899.21 KPA41406.1 - 6.9e-23 81.3 0.0 9.8e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family DUF5320 PF17253.2 KPA41407.1 - 6 8.0 11.8 7.4 7.7 7.7 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5320) DUF2431 PF10354.9 KPA41408.1 - 4.5e-60 202.7 0.0 9.5e-60 201.7 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) SRI PF08236.11 KPA41409.1 - 3.7e-22 78.3 4.5 1e-21 76.9 4.5 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KPA41409.1 - 8.5e-18 65.3 0.4 8.5e-18 65.3 0.4 2.8 4 1 0 4 4 4 1 SET domain AWS PF17907.1 KPA41409.1 - 6.2e-10 38.9 7.2 6.2e-10 38.9 7.2 2.5 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 KPA41409.1 - 6.6e-07 29.3 0.4 2.1e-06 27.6 0.4 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain KfrA_N PF11740.8 KPA41409.1 - 0.0072 17.0 2.4 0.03 15.0 2.4 2.1 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term WW PF00397.26 KPA41409.1 - 0.058 13.5 0.4 0.15 12.2 0.4 1.8 1 0 0 1 1 1 0 WW domain Vps51 PF08700.11 KPA41410.1 - 4.9e-13 49.0 0.0 1.9e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 Vps51/Vps67 REV1_C PF16727.5 KPA41410.1 - 0.14 12.6 1.4 0.84 10.1 0.4 3.0 3 0 0 3 3 2 0 DNA repair protein REV1 C-terminal domain DUF2457 PF10446.9 KPA41410.1 - 0.19 10.9 18.6 0.39 9.8 18.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF913 PF06025.12 KPA41410.1 - 0.23 10.4 4.8 0.58 9.1 4.8 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sporozoite_P67 PF05642.11 KPA41410.1 - 0.48 8.5 11.0 0.9 7.5 11.0 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DDHD PF02862.17 KPA41410.1 - 0.7 10.0 3.9 2 8.6 3.9 1.8 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.10 KPA41410.1 - 1.2 9.4 18.1 0.81 10.0 13.1 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 KPA41410.1 - 2 7.5 7.1 3.2 6.9 7.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 KPA41410.1 - 2.9 7.7 12.7 8.6 6.1 12.7 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PGA2 PF07543.12 KPA41410.1 - 2.9 7.9 20.0 0.34 10.9 10.3 3.0 3 0 0 3 3 3 0 Protein trafficking PGA2 CobT PF06213.12 KPA41410.1 - 3.7 6.9 17.3 9.5 5.5 17.3 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 KPA41410.1 - 4.6 5.2 21.6 9.6 4.2 21.6 1.5 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 KPA41410.1 - 5.2 7.5 7.9 12 6.3 7.9 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 KPA41410.1 - 9.4 4.9 9.5 15 4.2 9.5 1.2 1 0 0 1 1 1 0 Presenilin Sas10 PF09368.10 KPA41411.1 - 5.1e-29 100.6 6.1 5.1e-29 100.6 6.1 3.1 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KPA41411.1 - 3.4e-10 40.4 0.0 3.4e-10 40.4 0.0 3.0 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Fungal_trans PF04082.18 KPA41412.1 - 3e-13 49.4 1.2 6.2e-13 48.4 1.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Spc29 PF17082.5 KPA41412.1 - 0.072 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 TrbI_Ftype PF09677.10 KPA41412.1 - 0.16 12.3 0.1 30 5.0 0.0 2.5 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) Dynamin_N PF00350.23 KPA41413.1 - 1.3e-33 116.4 0.2 2.8e-33 115.3 0.2 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KPA41413.1 - 5.3e-27 94.8 0.0 2.6e-23 82.7 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KPA41413.1 - 6.9e-06 26.1 0.1 4.9e-05 23.4 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KPA41413.1 - 0.00097 19.2 0.7 0.028 14.6 0.0 3.0 3 0 0 3 3 3 1 Dynamin GTPase effector domain FeoB_N PF02421.18 KPA41413.1 - 0.13 11.8 0.0 7.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 KPA41413.1 - 0.16 12.2 0.0 0.64 10.3 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Sugar_tr PF00083.24 KPA41414.1 - 1.2e-48 166.1 13.6 1.8e-48 165.5 13.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA41414.1 - 8e-19 67.8 27.1 8e-19 67.8 27.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA41414.1 - 0.6 8.9 8.5 1.1 8.0 3.2 2.8 2 1 1 3 3 3 0 MFS_1 like family Abhydrolase_1 PF00561.20 KPA41415.1 - 4e-46 157.7 0.0 1.2e-45 156.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA41415.1 - 0.0064 17.1 4.6 0.034 14.8 4.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family THOC2_N PF16134.5 KPA41416.1 - 1.5e-247 823.3 0.0 2.2e-247 822.8 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KPA41416.1 - 2.6e-93 312.5 0.0 4.4e-93 311.8 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KPA41416.1 - 2.6e-26 91.5 0.1 5e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 Transcription- and export-related complex subunit WSC PF01822.19 KPA41417.1 - 2e-12 47.1 8.1 6.4e-12 45.5 8.1 1.9 1 0 0 1 1 1 1 WSC domain TMEM154 PF15102.6 KPA41417.1 - 1.6e-05 24.9 3.0 6.7e-05 22.8 3.0 2.0 1 1 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 KPA41417.1 - 7.5e-05 22.9 17.4 0.00016 21.9 17.0 1.6 1 1 0 1 1 1 1 Podoplanin VSP PF03302.13 KPA41417.1 - 0.00026 20.0 0.8 0.00026 20.0 0.8 1.7 2 0 0 2 2 2 1 Giardia variant-specific surface protein SKG6 PF08693.10 KPA41417.1 - 0.0015 17.9 2.8 0.003 16.9 2.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RIFIN PF02009.16 KPA41417.1 - 0.0042 17.0 0.0 0.0056 16.6 0.0 1.1 1 0 0 1 1 1 1 Rifin DUF4366 PF14283.6 KPA41417.1 - 0.0049 16.9 0.5 0.01 15.9 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Mid2 PF04478.12 KPA41417.1 - 0.0091 15.8 0.9 0.016 15.1 0.5 1.6 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4448 PF14610.6 KPA41417.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Syndecan PF01034.20 KPA41417.1 - 0.023 14.6 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain DUF5305 PF17231.2 KPA41417.1 - 0.033 13.6 0.9 0.069 12.5 0.7 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5305) CAGE1 PF15066.6 KPA41417.1 - 0.041 12.6 3.8 0.059 12.0 3.8 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family DUF4381 PF14316.6 KPA41417.1 - 0.044 14.0 0.0 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2207 PF09972.9 KPA41417.1 - 0.047 12.5 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.15 KPA41417.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4328 PF14219.6 KPA41417.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) EphA2_TM PF14575.6 KPA41417.1 - 0.089 13.7 0.0 0.25 12.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Trp_oprn_chp PF09534.10 KPA41417.1 - 0.19 11.5 2.8 0.45 10.3 2.8 1.7 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MtrF PF09472.10 KPA41417.1 - 0.21 11.0 2.9 0.44 10.0 2.9 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Macoilin PF09726.9 KPA41417.1 - 0.37 9.3 1.9 0.47 9.0 1.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF4064 PF13273.6 KPA41417.1 - 0.6 10.4 4.8 0.18 12.1 0.4 2.2 2 1 1 3 3 2 0 Protein of unknown function (DUF4064) Pap_E4 PF02711.14 KPA41417.1 - 7.7 7.6 10.2 0.97 10.4 5.0 2.3 2 0 0 2 2 1 0 E4 protein PI-PLC-X PF00388.19 KPA41418.1 - 9.2e-10 38.3 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Kelch_5 PF13854.6 KPA41419.1 - 0.003 17.5 3.2 1.6 8.8 0.3 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 KPA41419.1 - 0.0081 16.4 4.8 0.61 10.5 0.4 3.9 3 0 0 3 3 3 1 Kelch motif DUF347 PF03988.12 KPA41419.1 - 0.027 14.7 0.0 0.07 13.3 0.0 1.7 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) RSN1_7TM PF02714.15 KPA41420.1 - 1e-81 274.3 34.6 1e-81 274.3 34.6 3.1 4 0 0 4 4 4 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KPA41420.1 - 3e-47 160.3 1.6 3e-47 160.3 1.6 3.8 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KPA41420.1 - 1.5e-35 123.0 0.2 2.5e-35 122.3 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KPA41420.1 - 2.8e-34 117.2 0.5 8.9e-34 115.5 0.2 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter Radical_SAM PF04055.21 KPA41422.1 - 1e-07 32.5 0.0 1.6e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KPA41422.1 - 0.0008 19.7 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3878 PF12994.7 KPA41422.1 - 0.053 13.0 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3878) Proteasom_PSMB PF10508.9 KPA41423.1 - 0.18 10.3 0.1 0.24 9.8 0.1 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit DUF1681 PF07933.14 KPA41424.1 - 7.5e-58 194.4 0.2 1.1e-57 193.9 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) Se-cys_synth_N PF12390.8 KPA41424.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Selenocysteine synthase N terminal IF-2B PF01008.17 KPA41425.1 - 1.6e-44 152.3 0.0 1.9e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Methyltransf_33 PF10017.9 KPA41426.1 - 1.1e-81 274.4 0.0 1.5e-81 274.0 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KPA41426.1 - 2.7e-21 76.3 0.3 1.3e-20 74.1 0.3 2.0 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KPA41426.1 - 2.1e-05 25.0 0.3 6.5e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 DinB superfamily IRK_N PF08466.10 KPA41426.1 - 3.8 7.8 6.4 4 7.7 4.4 2.0 3 0 0 3 3 3 0 Inward rectifier potassium channel N-terminal Fungal_trans PF04082.18 KPA41427.1 - 1.2e-13 50.8 0.2 2.4e-13 49.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41427.1 - 2.8e-07 30.6 7.9 5.5e-07 29.6 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Senescence PF06911.12 KPA41428.1 - 5.3e-56 189.8 7.7 5.3e-56 189.8 7.7 2.0 2 0 0 2 2 2 1 Senescence-associated protein GCP_N_terminal PF17681.1 KPA41428.1 - 4e-29 102.2 0.2 6.5e-29 101.5 0.2 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KPA41428.1 - 1.7e-23 83.6 0.0 3.1e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal TPD52 PF04201.15 KPA41428.1 - 0.0024 17.5 3.0 0.011 15.3 0.4 2.9 3 0 0 3 3 3 1 Tumour protein D52 family DUF5526 PF17664.1 KPA41428.1 - 0.12 11.9 0.2 0.27 10.8 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5526) SDA1 PF05285.12 KPA41429.1 - 0.0028 17.1 21.5 0.0045 16.5 21.5 1.3 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 KPA41429.1 - 0.01 14.1 25.6 0.016 13.4 25.6 1.3 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 KPA41429.1 - 0.046 12.7 23.0 0.07 12.1 23.0 1.3 1 0 0 1 1 1 0 Paf1 DUF2052 PF09747.9 KPA41429.1 - 0.062 13.4 20.4 0.14 12.3 20.4 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Mpp10 PF04006.12 KPA41429.1 - 0.09 11.2 24.1 0.13 10.7 24.1 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF5523 PF17661.1 KPA41429.1 - 0.14 11.8 17.5 0.25 11.0 17.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Na_trans_assoc PF06512.13 KPA41429.1 - 1.9 8.7 21.6 3.9 7.7 21.6 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Tim54 PF11711.8 KPA41429.1 - 2.1 7.0 11.9 0.58 8.9 8.4 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF5614 PF18474.1 KPA41429.1 - 2.4 7.4 4.3 4.7 6.4 4.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5614) Connexin PF00029.19 KPA41429.1 - 4.5 7.0 4.3 7.3 6.3 4.3 1.4 1 0 0 1 1 1 0 Connexin FYDLN_acid PF09538.10 KPA41429.1 - 6.2 7.6 25.2 18 6.1 25.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDC27 PF09507.10 KPA41429.1 - 7.1 5.9 25.5 0.93 8.8 19.5 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SH3_1 PF00018.28 KPA41430.1 - 1.7e-09 37.1 0.4 1.7e-09 37.1 0.4 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KPA41430.1 - 3.1e-09 36.4 0.1 4.1e-08 32.8 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KPA41430.1 - 1.1e-08 34.8 0.5 2.6e-08 33.6 0.5 1.7 1 0 0 1 1 1 1 Variant SH3 domain DNase-RNase PF02577.14 KPA41430.1 - 0.032 13.9 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Bifunctional nuclease DNA_pol_phi PF04931.13 KPA41430.1 - 3.2 5.7 3.5 4.7 5.2 3.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi RPAP2_Rtr1 PF04181.13 KPA41431.1 - 2.6e-23 82.1 0.1 5.3e-23 81.1 0.1 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.18 KPA41432.1 - 8.7e-60 200.0 0.5 1e-59 199.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal S17 GUCT PF08152.12 KPA41432.1 - 0.14 12.4 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 GUCT (NUC152) domain Mit_ribos_Mrp51 PF11709.8 KPA41433.1 - 8.8e-121 403.9 0.2 1.1e-120 403.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit ADH_N PF08240.12 KPA41434.1 - 9.4e-30 102.7 6.0 1.1e-29 102.5 1.1 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA41434.1 - 3.1e-27 95.1 0.1 5.7e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA41434.1 - 0.00031 21.8 0.0 0.00066 20.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KPA41434.1 - 0.0012 18.2 1.4 0.0015 17.9 0.3 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ACP_syn_III_C PF08541.10 KPA41434.1 - 0.077 13.2 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2284 PF10050.9 KPA41434.1 - 0.088 12.5 2.4 0.86 9.3 0.2 2.3 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) FAD_binding_4 PF01565.23 KPA41435.1 - 1.6e-26 92.7 2.1 2.5e-26 92.1 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain Aa_trans PF01490.18 KPA41436.1 - 5.7e-26 91.2 33.0 7.2e-26 90.8 33.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spo7 PF03907.13 KPA41436.1 - 0.031 13.8 1.0 0.087 12.3 1.0 1.7 1 0 0 1 1 1 0 Spo7-like protein TNFR_16_TM PF18422.1 KPA41436.1 - 8.5 6.4 7.6 3.9 7.5 0.8 3.2 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain Radical_SAM_C PF16199.5 KPA41437.1 - 1.3e-31 108.5 0.0 2.5e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KPA41437.1 - 1.2e-16 61.5 0.2 5.1e-16 59.5 0.0 2.0 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KPA41437.1 - 2.5e-09 37.4 0.0 4.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA41437.1 - 9.1e-06 25.6 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA41437.1 - 0.01 16.2 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 KPA41438.1 - 1.9e-14 53.3 0.0 4.6e-09 36.1 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial carrier protein Exo_endo_phos PF03372.23 KPA41440.1 - 1.9e-17 63.6 0.1 6.9e-16 58.5 0.1 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KPA41440.1 - 4.5e-11 42.4 8.3 3.1e-06 26.9 0.4 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KPA41440.1 - 2.1e-07 31.1 5.6 0.016 15.6 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) p53-inducible11 PF14936.6 KPA41440.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 Methyltransf_25 PF13649.6 KPA41441.1 - 1.4e-13 51.3 0.0 2.6e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA41441.1 - 5.4e-10 39.8 0.0 9.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA41441.1 - 2.4e-08 34.0 0.0 4.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA41441.1 - 1.6e-06 28.8 0.0 3.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA41441.1 - 6.6e-05 22.7 0.0 0.00033 20.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KPA41441.1 - 0.072 14.1 0.0 0.17 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KPA41441.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KPA41441.1 - 0.16 12.0 0.0 0.47 10.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR PF05347.15 KPA41442.1 - 0.00031 20.7 0.3 0.00054 20.0 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KPA41442.1 - 0.013 16.2 1.0 0.018 15.8 1.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Macoilin PF09726.9 KPA41444.1 - 0.001 17.8 7.5 0.001 17.8 7.5 2.3 2 0 0 2 2 2 1 Macoilin family RAI16-like PF10257.9 KPA41445.1 - 1.8e-72 244.2 0.7 2.8e-72 243.6 0.7 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Katanin_con80 PF13925.6 KPA41445.1 - 0.15 12.1 0.3 6.3 6.8 0.1 2.5 2 0 0 2 2 2 0 con80 domain of Katanin T5orf172 PF10544.9 KPA41446.1 - 5.7e-25 87.9 0.0 1.2e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KPA41446.1 - 5.8e-24 84.6 0.1 1.1e-23 83.6 0.1 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 DUF1180 PF06679.12 KPA41446.1 - 0.21 12.0 3.2 2.4 8.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Sod_Fe_C PF02777.18 KPA41448.1 - 6.2e-34 116.2 0.4 8.6e-34 115.8 0.1 1.4 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KPA41448.1 - 5.2e-21 74.9 1.7 5.2e-21 74.9 1.7 2.1 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Kinesin PF00225.23 KPA41451.1 - 5.3e-105 351.0 0.4 5.3e-105 351.0 0.4 2.0 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KPA41451.1 - 1.5e-55 187.2 1.2 4.1e-55 185.8 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Bac_DnaA PF00308.18 KPA41451.1 - 0.0029 17.5 0.0 0.0029 17.5 0.0 2.4 2 1 1 3 3 3 1 Bacterial dnaA protein WEMBL PF05701.11 KPA41451.1 - 0.013 14.2 46.9 0.011 14.4 39.7 2.8 2 1 0 2 2 2 0 Weak chloroplast movement under blue light AAA_16 PF13191.6 KPA41451.1 - 0.042 14.2 0.0 0.042 14.2 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain bZIP_1 PF00170.21 KPA41451.1 - 0.042 13.9 0.4 0.042 13.9 0.4 5.3 3 1 2 5 5 5 0 bZIP transcription factor SHE3 PF17078.5 KPA41451.1 - 0.57 9.9 38.8 1.3 8.7 18.4 2.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Baculo_PEP_C PF04513.12 KPA41451.1 - 3.9 7.5 7.4 13 5.8 3.9 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Acyltransferase PF01553.21 KPA41452.1 - 1.4e-05 24.8 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ILVD_EDD PF00920.21 KPA41453.1 - 2e-212 706.4 0.2 2.3e-212 706.2 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Thioesterase PF00975.20 KPA41454.1 - 6e-10 39.6 0.0 4.9e-09 36.6 0.0 2.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KPA41454.1 - 0.00034 21.3 0.0 0.00041 21.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KPA41454.1 - 0.0081 16.0 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Caps_synth_GfcC PF06251.11 KPA41455.1 - 0.076 12.6 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC CLP_protease PF00574.23 KPA41456.1 - 1.5e-69 233.6 0.1 2e-69 233.1 0.1 1.1 1 0 0 1 1 1 1 Clp protease Melibiase_2 PF16499.5 KPA41457.1 - 1.7e-61 207.9 8.3 7.3e-61 205.8 8.3 1.9 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KPA41457.1 - 4.8e-08 33.0 0.2 8.8e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KPA41457.1 - 2.2e-06 26.9 0.1 4e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Melibiase DUF89 PF01937.19 KPA41458.1 - 1.5e-130 435.3 0.0 1.7e-130 435.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Fungal_trans_2 PF11951.8 KPA41459.1 - 9.5e-17 60.9 0.1 1.3e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHDPS PF00701.22 KPA41460.1 - 3.4e-50 170.4 0.0 4.1e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KPA41460.1 - 0.0046 16.4 0.1 0.0066 15.9 0.1 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Peripla_BP_4 PF13407.6 KPA41460.1 - 0.007 16.0 0.1 0.062 12.9 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein domain CbiD PF01888.17 KPA41460.1 - 0.033 13.5 0.1 0.056 12.7 0.1 1.3 1 0 0 1 1 1 0 CbiD Sugar_tr PF00083.24 KPA41461.1 - 4.9e-106 355.3 25.1 6.2e-106 355.0 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA41461.1 - 4.1e-25 88.4 22.7 4.1e-25 88.4 22.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA41462.1 - 1.3e-88 297.8 19.4 1.5e-88 297.6 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA41462.1 - 1.8e-19 69.9 18.7 1.8e-19 69.9 18.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM18 PF14770.6 KPA41462.1 - 0.061 13.3 1.3 0.3 11.1 1.3 2.2 1 0 0 1 1 1 0 Transmembrane protein 18 Glyco_hydro_32N PF00251.20 KPA41463.1 - 1e-31 110.7 0.0 1.5e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 KPA41463.1 - 0.0013 18.1 0.0 0.029 13.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.16 KPA41463.1 - 0.0015 17.5 0.0 0.0065 15.4 0.1 1.9 1 1 1 2 2 2 1 Levansucrase/Invertase Fungal_trans PF04082.18 KPA41464.1 - 2e-23 82.8 0.4 3.3e-23 82.1 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41464.1 - 7.5e-05 22.8 9.9 0.00014 21.9 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lar_restr_allev PF14354.6 KPA41464.1 - 0.25 11.8 2.5 0.51 10.8 2.5 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar 5_nucleotid_C PF02872.18 KPA41465.1 - 6.2e-34 117.5 0.1 1.5e-33 116.2 0.1 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KPA41465.1 - 1.2e-13 52.1 1.2 2.2e-13 51.2 1.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.6 KPA41465.1 - 0.00056 19.3 0.0 0.00098 18.5 0.0 1.4 1 0 0 1 1 1 1 YmdB-like protein DUF5026 PF16429.5 KPA41465.1 - 0.028 14.5 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) MFS_1 PF07690.16 KPA41466.1 - 1.6e-36 126.0 35.7 1.6e-36 126.0 35.7 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Barwin PF00967.17 KPA41467.1 - 0.08 12.8 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Barwin family DUF2153 PF09921.9 KPA41467.1 - 0.083 12.7 0.0 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) DUF2524 PF10732.9 KPA41467.1 - 2 8.8 4.4 0.56 10.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Aldo_ket_red PF00248.21 KPA41468.1 - 5.2e-51 173.6 0.1 2.7e-34 118.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DUF2963 PF11178.8 KPA41468.1 - 0.27 11.0 0.8 0.57 9.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) WD40 PF00400.32 KPA41469.1 - 2.1e-13 50.5 1.3 0.072 14.0 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA41469.1 - 0.00049 20.3 0.0 2 8.8 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KPA41469.1 - 0.13 12.8 0.9 0.69 10.5 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain EIF_2_alpha PF07541.12 KPA41470.1 - 2.2e-38 130.9 0.2 5.1e-38 129.7 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KPA41470.1 - 1.5e-13 50.8 0.8 2.9e-13 49.9 0.8 1.5 1 0 0 1 1 1 1 S1 RNA binding domain zf-U1 PF06220.12 KPA41471.1 - 0.2 11.4 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 U1 zinc finger Ras PF00071.22 KPA41472.1 - 8.6e-65 217.3 0.0 9.9e-65 217.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA41472.1 - 3.5e-34 117.6 0.1 6.2e-34 116.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA41472.1 - 2.6e-13 49.8 0.0 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPA41472.1 - 7.7e-06 25.6 0.0 1.6e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KPA41472.1 - 0.00019 20.9 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KPA41472.1 - 0.0023 18.0 0.0 0.0058 16.7 0.0 1.6 1 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA41472.1 - 0.005 16.8 0.2 2.7 7.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KPA41472.1 - 0.053 13.0 0.0 0.26 10.8 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 KPA41472.1 - 0.091 13.2 0.0 7 7.1 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA41472.1 - 0.092 13.0 0.1 0.94 9.7 0.0 2.1 1 1 0 2 2 2 0 AAA domain Glyco_hydro_61 PF03443.14 KPA41473.1 - 3e-51 174.3 0.0 7.1e-51 173.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Cpn10 PF00166.21 KPA41474.1 - 1.7e-29 101.7 0.0 1.9e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit 5-FTHF_cyc-lig PF01812.20 KPA41474.1 - 0.073 12.9 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family Pkinase PF00069.25 KPA41475.1 - 1.2e-48 165.8 0.0 3.4e-48 164.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA41475.1 - 5.2e-21 75.1 0.0 1.1e-20 74.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KPA41475.1 - 0.025 14.5 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KPA41475.1 - 0.036 13.0 0.0 0.074 12.0 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L11 PF00298.19 KPA41476.1 - 1.5e-27 95.9 0.3 3.2e-27 94.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KPA41476.1 - 1.3e-26 92.2 0.2 1.9e-26 91.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain KH_8 PF17903.1 KPA41477.1 - 2.6e-28 97.9 0.0 5.8e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain ADH_zinc_N PF00107.26 KPA41478.1 - 1.2e-18 67.4 0.5 1.9e-18 66.7 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA41478.1 - 1.1e-10 42.6 0.0 4.2e-10 40.8 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA41478.1 - 0.004 17.0 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sulf_transp PF04143.14 KPA41479.1 - 3.3e-28 99.2 23.3 4.8e-27 95.3 23.3 2.0 1 1 0 1 1 1 1 Sulphur transport Ribonuc_L-PSP PF01042.21 KPA41480.1 - 5.1e-19 68.5 0.2 5.4e-18 65.2 0.2 1.9 1 1 0 1 1 1 1 Endoribonuclease L-PSP YqeY PF09424.10 KPA41481.1 - 3.3e-22 79.1 10.7 4.1e-22 78.8 10.7 1.1 1 0 0 1 1 1 1 Yqey-like protein Methyltransf_11 PF08241.12 KPA41482.1 - 1e-07 32.5 0.0 1.7e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA41482.1 - 1.4e-07 31.5 0.0 1.7e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA41482.1 - 8.8e-07 29.6 0.0 1.4e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA41482.1 - 0.00012 21.9 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA41482.1 - 0.0016 19.2 0.0 0.0024 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA41482.1 - 0.033 13.5 0.0 0.21 10.9 0.0 1.9 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family PI3_PI4_kinase PF00454.27 KPA41483.1 - 3.2e-44 151.6 0.0 4.9e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PPR PF01535.20 KPA41485.1 - 4.5e-21 73.6 5.7 0.0027 17.8 0.0 9.1 10 0 0 10 10 10 4 PPR repeat PPR_2 PF13041.6 KPA41485.1 - 4.6e-19 68.3 1.7 0.00069 19.8 0.1 7.8 6 1 1 7 7 7 3 PPR repeat family PPR_3 PF13812.6 KPA41485.1 - 3.2e-09 36.7 0.0 2.1e-05 24.5 0.0 4.0 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 KPA41485.1 - 5.1e-07 29.3 0.3 0.0019 17.6 0.0 2.9 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KPA41485.1 - 2e-06 28.1 0.1 2.4 9.2 0.0 6.6 5 2 2 7 7 7 1 Tetratricopeptide repeat PPR_1 PF12854.7 KPA41485.1 - 0.00018 21.2 0.0 12 5.7 0.0 5.4 6 0 0 6 6 6 1 PPR repeat Suf PF05843.14 KPA41485.1 - 0.004 17.2 0.6 3.4 7.6 0.1 2.7 1 1 0 2 2 2 2 Suppressor of forked protein (Suf) Catalase-rel PF06628.12 KPA41485.1 - 0.043 14.0 0.1 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 Catalase-related immune-responsive TPR_19 PF14559.6 KPA41485.1 - 0.061 13.8 0.1 8 7.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat SPOB_a PF14689.6 KPA41485.1 - 0.15 11.8 1.4 13 5.6 0.1 4.1 5 0 0 5 5 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF4210 PF13915.6 KPA41486.1 - 3.8e-33 113.9 0.2 1.1e-32 112.5 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KPA41486.1 - 3.4e-21 75.1 0.2 7.7e-21 74.0 0.2 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF3367 PF11847.8 KPA41487.1 - 0.0008 17.4 1.0 0.00098 17.1 1.0 1.1 1 0 0 1 1 1 1 Alpha-(1->3)-arabinofuranosyltransferase rRNA_processing PF08524.11 KPA41487.1 - 0.0023 18.0 26.5 0.0065 16.5 26.5 1.7 1 1 0 1 1 1 1 rRNA processing RhoGAP PF00620.27 KPA41488.1 - 2.5e-46 157.3 2.1 6.5e-46 155.9 0.0 2.6 2 1 1 3 3 3 1 RhoGAP domain LIM PF00412.22 KPA41488.1 - 2.8e-13 49.9 17.0 6.5e-09 35.9 1.9 2.5 2 0 0 2 2 2 2 LIM domain DUF4407 PF14362.6 KPA41488.1 - 1.3 8.3 5.7 3.1 7.1 5.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Desulfoferrod_N PF06397.12 KPA41488.1 - 4.1 7.1 8.4 21 4.8 0.0 3.6 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain CLASP_N PF12348.8 KPA41490.1 - 2.6e-129 429.5 0.2 6.1e-85 284.4 0.0 3.1 4 0 0 4 4 4 2 CLASP N terminal HEAT_2 PF13646.6 KPA41490.1 - 0.00027 21.3 2.6 1.3 9.4 0.1 4.7 4 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 KPA41490.1 - 0.00075 19.5 1.7 1.8 9.1 0.0 4.9 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 KPA41490.1 - 0.019 15.0 0.1 5.3 7.1 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KPA41490.1 - 0.033 14.8 0.0 11 6.7 0.0 3.3 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KPA41490.1 - 0.059 11.9 0.6 0.36 9.3 0.0 2.6 4 0 0 4 4 4 0 Adaptin N terminal region BSP PF04450.12 KPA41491.1 - 2.8e-75 252.7 0.0 3.2e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 KPA41491.1 - 0.045 13.6 0.2 0.072 13.0 0.2 1.3 1 0 0 1 1 1 0 SprT-like family TFIIB PF00382.19 KPA41494.1 - 0.00077 19.5 0.0 0.29 11.2 0.0 2.8 2 1 0 2 2 2 2 Transcription factor TFIIB repeat DUF2448 PF10476.9 KPA41494.1 - 0.085 12.7 0.1 0.22 11.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) WD40 PF00400.32 KPA41495.1 - 2e-08 34.8 10.3 0.00031 21.5 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KPA41495.1 - 0.02 13.9 0.2 6.2 5.7 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KPA41495.1 - 0.024 14.9 0.1 6.5 7.1 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain BNR PF02012.20 KPA41495.1 - 0.072 13.1 0.8 0.32 11.2 0.8 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat FA_desaturase PF00487.24 KPA41496.1 - 1.8e-19 70.6 14.5 1.8e-19 70.6 14.5 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KPA41496.1 - 5.3e-17 61.7 0.1 1.1e-16 60.7 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Oleosin PF01277.17 KPA41496.1 - 0.014 15.2 0.7 0.047 13.4 0.7 1.9 1 0 0 1 1 1 0 Oleosin Ribosomal_S8 PF00410.19 KPA41498.1 - 5.6e-11 42.5 0.0 2.8e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S8 FAD_binding_3 PF01494.19 KPA41499.1 - 1.9e-19 70.2 0.0 3.8e-19 69.1 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA41499.1 - 3.2e-06 26.6 0.0 5.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA41499.1 - 3.5e-05 23.9 0.0 9.7e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA41499.1 - 0.00049 19.8 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA41499.1 - 0.00066 20.2 0.0 0.0023 18.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA41499.1 - 0.00075 18.7 0.1 0.0021 17.2 0.1 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KPA41499.1 - 0.001 17.9 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KPA41499.1 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KPA41499.1 - 0.012 15.0 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KPA41499.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 KPA41499.1 - 0.03 13.4 0.0 0.078 12.0 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase AIRS_C PF02769.22 KPA41499.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain FAD_binding_2 PF00890.24 KPA41499.1 - 0.094 11.8 0.0 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KPA41499.1 - 0.2 10.5 0.0 0.63 8.8 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Peptidase_M24 PF00557.24 KPA41500.1 - 5.2e-49 166.8 0.1 6.4e-49 166.5 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KPA41500.1 - 1.3e-21 76.7 6.9 1.3e-21 76.7 6.9 1.8 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KPA41500.1 - 6.9e-05 22.9 3.4 6.9e-05 22.9 3.4 2.1 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 KPA41500.1 - 3.7 7.5 7.8 0.53 10.2 3.4 2.0 2 0 0 2 2 2 0 HIT zinc finger Cornichon PF03311.14 KPA41501.1 - 6.5e-50 168.5 11.0 7.4e-50 168.4 11.0 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 KPA41502.1 - 3.5e-31 106.8 6.2 2.7e-06 28.0 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA41502.1 - 1.6e-14 53.9 0.1 8.3e-05 22.8 0.0 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain SET PF00856.28 KPA41503.1 - 1.4e-08 35.3 0.4 1.2e-07 32.3 0.1 2.4 2 1 0 2 2 2 1 SET domain CPP1-like PF11833.8 KPA41504.1 - 0.019 14.7 2.2 0.019 14.7 2.2 2.0 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF371 PF04027.13 KPA41504.1 - 0.16 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF371) FMN_red PF03358.15 KPA41505.1 - 1.3e-07 31.4 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 KPA41505.1 - 2.4e-05 24.6 0.3 7.6e-05 22.9 0.3 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 KPA41505.1 - 7.1e-05 22.6 0.0 8.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 KPA41505.1 - 0.0026 18.0 0.0 0.16 12.2 0.0 2.2 1 1 1 2 2 2 1 Flavodoxin domain CR6_interact PF10147.9 KPA41507.1 - 0.0037 17.0 2.9 0.0062 16.3 2.9 1.4 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 PCM1_C PF15717.5 KPA41507.1 - 0.33 9.6 14.0 0.49 9.0 14.0 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Miga PF10265.9 KPA41507.1 - 7.9 5.3 13.2 11 4.9 13.2 1.1 1 0 0 1 1 1 0 Mitoguardin IMS PF00817.20 KPA41509.1 - 1.8e-42 144.9 0.6 3.6e-42 143.9 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KPA41509.1 - 8e-15 55.6 0.1 2e-14 54.3 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KPA41509.1 - 0.0037 17.5 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif TrkH PF02386.16 KPA41510.1 - 1.8e-102 343.4 2.1 4.5e-99 332.2 0.0 2.1 2 0 0 2 2 2 2 Cation transport protein SieB PF14163.6 KPA41510.1 - 0.17 11.4 0.7 2.1 7.9 0.1 2.3 2 0 0 2 2 2 0 Super-infection exclusion protein B FKBP_C PF00254.28 KPA41511.1 - 2.3e-32 111.2 0.0 3.7e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EspB PF05802.11 KPA41511.1 - 0.047 13.7 7.4 0.077 13.0 7.4 1.3 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF1512 PF07431.12 KPA41511.1 - 0.21 10.5 5.2 0.29 10.1 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Adeno_PV PF03910.13 KPA41511.1 - 0.36 9.5 3.7 0.5 9.0 3.7 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV SR-25 PF10500.9 KPA41512.1 - 0.12 12.0 3.0 0.13 11.9 3.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAP1 PF08601.10 KPA41512.1 - 5.9 6.5 8.9 6.5 6.4 8.9 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 RPEL PF02755.15 KPA41513.1 - 2.9e-18 64.9 6.2 1.5e-09 37.2 1.1 2.5 2 0 0 2 2 2 2 RPEL repeat Myosin_head PF00063.21 KPA41514.1 - 5.4e-239 794.9 1.0 6.6e-239 794.6 1.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KPA41514.1 - 6.9e-48 162.8 0.0 1.2e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KPA41514.1 - 3.6e-12 45.7 0.1 6.8e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPA41514.1 - 2.8e-09 36.7 0.0 6.9e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPA41514.1 - 1.2e-05 24.8 0.0 2.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 KPA41514.1 - 0.005 16.5 10.0 0.17 11.8 2.4 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.12 KPA41514.1 - 0.035 13.6 0.6 5.3 6.5 0.1 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 KPA41514.1 - 0.055 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KPA41514.1 - 0.096 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SH3_3 PF08239.11 KPA41514.1 - 0.097 13.0 0.1 0.3 11.4 0.1 1.9 1 0 0 1 1 1 0 Bacterial SH3 domain NACHT PF05729.12 KPA41514.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain DUF4913 PF16259.5 KPA41514.1 - 0.22 11.6 1.4 0.54 10.3 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) DHHC PF01529.20 KPA41515.1 - 1.4e-29 102.9 6.0 1.4e-29 102.9 6.0 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 KPA41515.1 - 0.89 9.5 5.3 0.16 11.8 1.4 1.7 2 0 0 2 2 2 0 Transglutaminase-like superfamily Glyco_transf_90 PF05686.12 KPA41516.1 - 0.012 14.6 0.0 0.15 10.9 0.1 2.5 2 1 0 2 2 2 0 Glycosyl transferase family 90 DNA_binding_2 PF13724.6 KPA41516.1 - 0.043 14.2 0.7 0.099 13.1 0.7 1.5 1 0 0 1 1 1 0 DNA-binding domain Spc7 PF08317.11 KPA41518.1 - 0.00066 18.7 194.7 0.0031 16.5 31.6 7.4 1 1 7 8 8 8 4 Spc7 kinetochore protein NBP1 PF08537.10 KPA41518.1 - 0.0007 19.1 8.0 0.0007 19.1 8.0 6.1 1 1 4 5 5 5 1 Fungal Nap binding protein NBP1 CCDC144C PF14915.6 KPA41518.1 - 0.0031 16.7 34.3 0.0031 16.7 34.3 5.7 2 2 2 4 4 4 1 CCDC144C protein coiled-coil region ATG16 PF08614.11 KPA41518.1 - 0.0059 16.9 200.4 0.32 11.2 20.8 9.1 2 1 7 9 9 9 6 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 KPA41518.1 - 0.015 15.4 8.7 0.015 15.4 8.7 14.0 8 3 5 14 14 14 0 bZIP transcription factor Filament PF00038.21 KPA41518.1 - 3.6 7.1 160.2 0.3 10.6 54.9 6.3 1 1 2 4 4 4 0 Intermediate filament protein GAS PF13851.6 KPA41518.1 - 6 6.2 185.5 0.074 12.4 12.9 9.0 1 1 9 10 10 10 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KPA41518.1 - 7.4 6.6 107.5 0.97 9.5 5.1 10.7 2 2 7 11 11 11 0 Protein of unknown function (DUF1664) MAD PF05557.13 KPA41518.1 - 9.4 4.5 176.7 0.11 10.9 34.3 4.7 1 1 2 4 4 4 0 Mitotic checkpoint protein DUF2012 PF09430.10 KPA41519.1 - 1.4e-24 86.6 0.0 2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) WW PF00397.26 KPA41520.1 - 2.2e-09 37.3 5.0 3.7e-09 36.5 5.0 1.4 1 0 0 1 1 1 1 WW domain LtrA PF06772.11 KPA41521.1 - 7.2e-36 124.1 29.5 1e-35 123.6 29.5 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Rdx PF10262.9 KPA41521.1 - 0.19 11.9 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 Rdx family ENOD93 PF03386.14 KPA41521.1 - 0.35 10.8 2.5 2 8.3 0.3 2.4 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein Strumpellin PF10266.9 KPA41522.1 - 0.033 11.9 0.0 0.038 11.7 0.0 1.1 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin Cys_Met_Meta_PP PF01053.20 KPA41523.1 - 2.7e-152 506.8 0.0 3e-152 506.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KPA41523.1 - 2.2e-11 43.7 0.5 4.5e-11 42.7 0.1 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KPA41523.1 - 4.2e-09 36.0 0.0 6.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KPA41523.1 - 3e-08 33.3 0.0 5.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KPA41523.1 - 3.8e-08 32.7 0.2 5.4e-08 32.2 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 KPA41523.1 - 5.5e-05 21.9 0.0 7.6e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 KPA41523.1 - 0.05 12.4 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein CPSase_L_D2 PF02786.17 KPA41523.1 - 0.42 10.1 1.3 0.52 9.8 0.1 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain MARVEL PF01284.23 KPA41524.1 - 7.9e-11 42.2 12.5 9.3e-11 41.9 12.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain AMP-binding PF00501.28 KPA41525.1 - 5.6e-84 282.2 0.0 6.5e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.32 KPA41526.1 - 1.2e-06 29.1 4.8 2.1 9.4 0.0 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Mito_carr PF00153.27 KPA41527.1 - 4.4e-30 103.5 3.7 1.9e-13 50.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.21 KPA41528.1 - 5.1e-99 331.7 0.0 6.6e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 KPA41528.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone Smr PF01713.21 KPA41528.1 - 0.082 13.3 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Smr domain OPT PF03169.15 KPA41529.1 - 1e-161 539.7 43.8 1.2e-161 539.5 43.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 7tm_6 PF02949.20 KPA41529.1 - 0.35 9.9 7.7 0.12 11.5 1.4 2.9 3 0 0 3 3 3 0 7tm Odorant receptor PAN_4 PF14295.6 KPA41530.1 - 0.0011 18.8 0.5 0.0026 17.6 0.5 1.6 1 0 0 1 1 1 1 PAN domain MANEC PF07502.14 KPA41530.1 - 0.071 13.4 0.1 0.39 11.0 0.1 2.3 1 0 0 1 1 1 0 MANEC domain NOA36 PF06524.12 KPA41531.1 - 0.022 14.1 1.7 0.032 13.5 1.7 1.2 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_16 PF00722.21 KPA41532.1 - 1.5e-40 138.5 2.7 3.9e-40 137.2 2.7 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF664 PF04978.12 KPA41532.1 - 0.47 10.9 4.8 1 9.8 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF664) PARG_cat PF05028.14 KPA41533.1 - 4.5e-46 157.7 0.0 5.8e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Pec_lyase_C PF00544.19 KPA41534.1 - 1.2e-48 165.5 10.5 1.7e-48 165.0 10.5 1.2 1 0 0 1 1 1 1 Pectate lyase Peptidase_M4_C PF02868.15 KPA41535.1 - 2.1e-44 151.3 0.0 3.2e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain PLN_propep PF16485.5 KPA41535.1 - 2.5e-20 71.9 2.5 1.9e-14 53.1 0.1 2.4 2 0 0 2 2 2 2 Protealysin propeptide Peptidase_M4 PF01447.18 KPA41535.1 - 2.8e-19 70.1 0.1 4.7e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain UTRA PF07702.13 KPA41535.1 - 0.031 14.1 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 UTRA domain Sec63 PF02889.16 KPA41536.1 - 2.9e-17 62.7 0.0 3.8e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain HHH_5 PF14520.6 KPA41536.1 - 0.021 15.4 0.0 0.047 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KPA41536.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda DUF126 PF01989.16 KPA41537.1 - 2.6 7.9 4.4 15 5.5 0.2 3.1 3 0 0 3 3 3 0 Aconitase X swivel domain Band_7 PF01145.25 KPA41538.1 - 4.9e-30 104.8 0.6 1.1e-29 103.7 0.6 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KPA41538.1 - 2e-23 82.2 1.5 4.2e-23 81.2 0.1 2.3 3 0 0 3 3 3 1 C-terminal region of band_7 Pox_A11 PF05061.13 KPA41538.1 - 0.021 14.1 0.2 0.032 13.5 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein UQ_con PF00179.26 KPA41539.1 - 2.4e-16 59.7 0.0 2.7e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KPA41539.1 - 0.01 16.1 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain AA_permease PF00324.21 KPA41541.1 - 3.4e-95 319.4 36.3 5.9e-95 318.6 36.3 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA41541.1 - 3.7e-30 105.1 31.7 6.3e-30 104.3 31.7 1.4 1 1 0 1 1 1 1 Amino acid permease Flavoprotein PF02441.19 KPA41542.1 - 7.9e-20 71.2 0.0 1.4e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein Diacid_rec PF05651.13 KPA41542.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative sugar diacid recognition Pribosyltran_N PF13793.6 KPA41543.1 - 3.5e-42 143.0 0.1 7.4e-42 142.0 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KPA41543.1 - 4.6e-42 144.1 1.0 8.1e-35 120.5 0.5 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KPA41543.1 - 3.2e-15 56.0 0.2 6.2e-15 55.1 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KPA41543.1 - 0.0061 16.0 0.1 0.0099 15.3 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase FtsJ PF01728.19 KPA41544.1 - 7.9e-61 205.2 0.0 2.1e-60 203.9 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase DCB PF16213.5 KPA41544.1 - 1.6e-48 164.8 11.2 1.1e-47 161.9 6.2 3.7 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KPA41544.1 - 4.3e-43 146.9 6.7 1.8e-42 145.0 0.0 4.8 6 1 0 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KPA41544.1 - 3.6e-27 94.9 6.8 7.1e-22 77.4 0.6 3.4 3 0 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 KPA41544.1 - 3.4e-06 26.8 0.5 0.0026 17.6 0.0 4.5 4 1 1 5 5 5 1 Domain of unknown function (DUF1981) Acetyltransf_1 PF00583.25 KPA41545.1 - 1.4e-10 41.5 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA41545.1 - 2.4e-07 30.7 0.0 3.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA41545.1 - 4.4e-07 30.2 0.0 8e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA41545.1 - 1.2e-06 28.4 0.0 7.3e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 KPA41545.1 - 0.045 13.8 0.1 0.073 13.2 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA41545.1 - 0.093 12.9 0.0 0.27 11.4 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Cwf_Cwc_15 PF04889.12 KPA41546.1 - 1.2 8.8 4.6 1.6 8.4 4.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SIR2 PF02146.17 KPA41547.1 - 9.1e-38 129.9 0.0 1.5e-37 129.3 0.0 1.3 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KPA41547.1 - 0.069 12.9 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Meiosis_expr PF15163.6 KPA41547.1 - 0.11 13.2 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 Meiosis-expressed DUF572 PF04502.13 KPA41548.1 - 1.2e-69 235.5 0.0 1.3e-69 235.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) UQ_con PF00179.26 KPA41549.1 - 6.7e-35 119.8 0.0 7.9e-35 119.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pantoate_transf PF02548.15 KPA41550.1 - 2.8e-106 354.6 0.3 4.3e-106 354.1 0.3 1.2 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KPA41550.1 - 7.8e-10 38.6 0.1 1.4e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 KPA41550.1 - 0.11 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) APG12 PF04110.13 KPA41551.1 - 7.6e-27 93.6 0.0 1.2e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KPA41551.1 - 0.00055 20.1 0.0 0.00066 19.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Lyase_aromatic PF00221.19 KPA41552.1 - 5e-148 493.6 3.8 6.2e-148 493.3 3.8 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Dfp1_Him1_M PF08630.10 KPA41553.1 - 2.5e-44 150.6 1.2 4.1e-44 149.8 0.0 2.1 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 KPA41553.1 - 1.1e-21 76.6 0.6 2.5e-21 75.5 0.6 1.6 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 KPA41553.1 - 0.082 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain Peptidase_M24 PF00557.24 KPA41554.1 - 9.6e-47 159.4 0.0 1.7e-46 158.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KPA41554.1 - 1.8e-33 114.9 0.1 2.8e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HLH PF00010.26 KPA41555.1 - 1.6e-16 60.0 1.0 3.8e-16 58.8 0.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SLX9 PF15341.6 KPA41555.1 - 0.43 11.0 7.2 0.053 13.9 1.8 2.3 2 1 1 3 3 3 0 Ribosome biogenesis protein SLX9 Tht1 PF04163.12 KPA41556.1 - 0.0015 17.4 1.5 0.0063 15.3 0.1 2.1 1 1 1 2 2 2 1 Tht1-like nuclear fusion protein DUF4344 PF14247.6 KPA41556.1 - 0.051 13.2 0.3 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 Putative metallopeptidase DUF3958 PF13125.6 KPA41556.1 - 0.09 13.0 1.7 0.19 11.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) DUF2615 PF11027.8 KPA41556.1 - 0.096 12.8 0.2 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Apolipoprotein PF01442.18 KPA41556.1 - 0.5 10.2 11.6 1.4 8.8 11.5 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Rrn6 PF10214.9 KPA41557.1 - 0.12 10.8 2.4 0.16 10.5 2.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Sin3a_C PF16879.5 KPA41558.1 - 8.6e-77 258.7 2.1 8.6e-77 258.7 2.1 2.2 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 KPA41558.1 - 3e-42 142.5 7.2 8.2e-18 64.3 0.0 4.5 3 1 1 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KPA41558.1 - 1e-40 137.7 0.4 1e-39 134.5 0.0 2.6 2 0 0 2 2 2 1 Sin3 family co-repressor TSP_NTD PF17804.1 KPA41558.1 - 2.9 8.1 15.5 0.22 11.7 0.2 3.8 3 1 0 4 4 4 0 Tail specific protease N-terminal domain FRG1 PF06229.12 KPA41559.1 - 5.2e-51 173.1 0.1 5.2e-51 173.1 0.1 1.5 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 KPA41559.1 - 0.00022 21.4 0.0 0.0015 18.7 0.0 2.2 1 1 1 2 2 2 1 Fascin domain bZIP_Maf PF03131.17 KPA41559.1 - 0.034 14.7 2.2 0.034 14.7 2.2 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF569 PF04601.13 KPA41559.1 - 0.15 11.8 0.9 0.59 9.8 0.0 2.3 4 0 0 4 4 4 0 Domain of unknown function (DUF569) PAF-AH_p_II PF03403.13 KPA41560.1 - 8.9e-40 136.4 0.0 1.2e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KPA41560.1 - 6.4e-06 25.3 0.0 9.9e-05 21.4 0.0 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KPA41560.1 - 0.0065 15.5 0.0 0.027 13.5 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase DUF1284 PF06935.11 KPA41561.1 - 0.12 12.9 1.1 0.38 11.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) Peptidase_S8 PF00082.22 KPA41562.1 - 8.7e-36 123.7 5.2 1.3e-35 123.1 5.2 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KPA41562.1 - 3.9e-21 75.5 0.1 8.8e-21 74.4 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Phasin PF05597.11 KPA41562.1 - 0.081 12.9 0.3 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.18 KPA41562.1 - 0.12 12.2 0.3 0.3 10.9 0.3 1.6 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Big_2 PF02368.18 KPA41563.1 - 0.24 11.3 0.6 0.64 9.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Beach PF02138.18 KPA41564.1 - 3e-119 397.5 0.0 5e-119 396.7 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KPA41564.1 - 1.3e-10 41.3 0.0 3.9e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KPA41564.1 - 1.7e-10 41.3 0.1 3.6e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KPA41564.1 - 0.0015 19.3 1.8 9.3 7.3 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat NADHdh_A3 PF14987.6 KPA41565.1 - 0.053 13.8 0.4 0.067 13.5 0.4 1.2 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DDOST_48kD PF03345.14 KPA41566.1 - 2.4e-156 520.8 0.0 2.7e-156 520.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Isy1 PF06246.12 KPA41568.1 - 5.6e-91 304.6 1.8 6.5e-91 304.4 1.8 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 KPA41568.1 - 0.0039 17.2 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 YolD-like protein Abhydrolase_1 PF00561.20 KPA41570.1 - 8.4e-46 156.7 0.0 2.9e-45 154.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KPA41570.1 - 0.00037 20.2 0.0 0.0006 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KPA41570.1 - 0.054 13.3 0.3 0.096 12.5 0.1 1.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Glyco_hydro_16 PF00722.21 KPA41572.1 - 2.4e-09 36.9 4.9 3.4e-09 36.4 4.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 KPA41574.1 - 3.6e-17 62.3 15.9 3.6e-17 62.3 15.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KPA41574.1 - 0.36 9.1 9.8 0.015 13.6 2.9 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3040 PF11239.8 KPA41574.1 - 0.43 10.9 0.1 0.43 10.9 0.1 4.0 4 2 0 4 4 4 0 Protein of unknown function (DUF3040) Mtc PF03820.17 KPA41574.1 - 0.76 8.8 4.5 7 5.6 1.4 2.5 1 1 1 2 2 2 0 Tricarboxylate carrier PCI PF01399.27 KPA41575.1 - 1.7e-16 60.6 0.8 8.1e-16 58.4 0.1 2.2 2 0 0 2 2 2 1 PCI domain TPR_1 PF00515.28 KPA41575.1 - 0.016 15.0 2.3 0.49 10.3 0.4 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPA41575.1 - 0.055 13.6 5.3 0.11 12.6 0.4 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KPA41575.1 - 0.056 13.5 0.8 1.7 8.9 0.1 3.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KPA41575.1 - 0.094 13.0 0.5 6.1 7.2 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KPA41575.1 - 0.2 11.4 1.3 0.73 9.6 0.2 2.4 2 0 0 2 2 2 0 TPR repeat Peptidase_C65 PF10275.9 KPA41576.1 - 2.8e-60 203.8 0.0 3.8e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Methyltransf_23 PF13489.6 KPA41577.1 - 1.3e-12 47.8 0.0 2.2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA41577.1 - 1.4e-12 48.1 0.0 3.3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA41577.1 - 6e-11 42.9 0.0 1.2e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA41577.1 - 5.8e-10 39.8 0.0 1.5e-09 38.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA41577.1 - 9.6e-10 38.5 0.0 2.9e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA41577.1 - 1e-05 25.1 0.0 3.8e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KPA41577.1 - 5.1e-05 22.8 0.0 0.00023 20.7 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 KPA41577.1 - 0.0017 17.7 0.0 0.0042 16.4 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 KPA41577.1 - 0.0061 15.9 0.0 0.026 13.9 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KPA41577.1 - 0.022 14.1 0.0 0.068 12.4 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 KPA41577.1 - 0.042 13.7 0.0 0.2 11.5 0.0 1.9 1 1 1 2 2 2 0 Hypothetical methyltransferase Methyltransf_32 PF13679.6 KPA41577.1 - 0.2 11.7 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NUDIX PF00293.28 KPA41578.1 - 7.6e-08 32.5 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KPA41579.1 - 1.6e-16 60.5 0.4 4.4e-16 59.1 0.1 1.8 2 0 0 2 2 2 1 NUDIX domain Gln-synt_C PF00120.24 KPA41580.1 - 1.5e-89 300.4 0.0 1.8e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain GST_N PF02798.20 KPA41580.1 - 0.037 14.4 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain adh_short_C2 PF13561.6 KPA41581.1 - 1.6e-58 198.1 0.1 1.8e-58 197.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA41581.1 - 1.5e-41 142.0 0.1 1.8e-41 141.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA41581.1 - 4.7e-10 39.7 0.7 7.3e-10 39.0 0.7 1.2 1 0 0 1 1 1 1 KR domain ChuX_HutX PF06228.13 KPA41581.1 - 0.00098 18.9 0.0 0.89 9.3 0.0 2.3 1 1 1 2 2 2 2 Haem utilisation ChuX/HutX Methyltransf_25 PF13649.6 KPA41581.1 - 0.0036 18.0 0.0 0.0075 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 KPA41581.1 - 0.0038 17.1 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 KPA41581.1 - 0.014 16.2 0.0 0.029 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RecC_C PF17946.1 KPA41581.1 - 0.028 14.2 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 RecC C-terminal domain THF_DHG_CYH_C PF02882.19 KPA41581.1 - 0.082 12.2 0.1 0.21 10.9 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ICL PF00463.21 KPA41582.1 - 1.5e-199 663.9 0.2 1.8e-199 663.7 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Citrate_synt PF00285.21 KPA41583.1 - 2.5e-101 339.4 0.0 3e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Acetyltransf_10 PF13673.7 KPA41584.1 - 1.4e-08 34.7 0.0 8e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA41584.1 - 5.3e-07 29.9 0.0 6.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA41584.1 - 8.1e-05 23.0 0.0 0.00012 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_16 PF00722.21 KPA41585.1 - 1.5e-34 119.0 4.6 2.6e-34 118.2 4.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GST_N_3 PF13417.6 KPA41586.1 - 1.6e-17 63.6 0.0 3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPA41586.1 - 2.4e-14 53.4 0.0 4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPA41586.1 - 7.1e-13 48.7 0.0 1.1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KPA41586.1 - 1.5e-05 25.1 0.0 2.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 KPA41586.1 - 0.02 14.9 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KPA41586.1 - 0.06 13.9 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA41586.1 - 0.076 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain rhaM PF05336.13 KPA41587.1 - 0.12 12.5 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 L-rhamnose mutarotase Ras PF00071.22 KPA41589.1 - 2.3e-53 180.1 0.0 2.7e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA41589.1 - 8.1e-22 77.7 0.0 1.5e-21 76.8 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA41589.1 - 3.1e-08 33.3 0.0 5.6e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KPA41589.1 - 0.003 16.9 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KPA41589.1 - 0.0049 16.1 0.0 0.012 14.8 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 KPA41589.1 - 0.0068 15.9 0.0 0.0096 15.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPA41589.1 - 0.024 14.7 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KPA41589.1 - 0.074 12.8 0.0 3.1 7.5 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KPA41589.1 - 0.12 12.9 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CWC25 PF12542.8 KPA41590.1 - 3.4e-26 92.1 1.1 3.4e-26 92.1 1.1 4.0 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KPA41590.1 - 9.7e-14 51.3 6.2 9.7e-14 51.3 6.2 5.0 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Ribosomal_S14 PF00253.21 KPA41591.1 - 5.4e-21 74.1 0.7 1e-20 73.2 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Glyco_hydro_3_C PF01915.22 KPA41592.1 - 5.1e-47 160.5 0.0 9.5e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPA41592.1 - 6e-44 150.7 0.0 9.6e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPA41592.1 - 2.3e-27 94.9 0.2 4e-27 94.1 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain WYL_2 PF10902.8 KPA41592.1 - 0.82 10.1 3.4 0.47 10.9 0.3 2.4 2 1 0 2 2 2 0 WYL_2, Sm-like SH3 beta-barrel fold Glyco_hydro_88 PF07470.13 KPA41593.1 - 7e-95 318.0 3.9 7.9e-95 317.8 3.9 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KPA41593.1 - 0.0017 16.9 1.2 0.0024 16.4 1.2 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 KPA41593.1 - 0.23 11.0 9.7 0.98 8.9 0.3 3.3 2 1 2 4 4 4 0 Glycosyl hydrolase family 76 DUF3615 PF12274.8 KPA41594.1 - 0.031 14.8 1.3 0.046 14.2 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3615) zf-RanBP PF00641.18 KPA41594.1 - 5.1 6.5 11.0 2.5 7.5 8.4 1.8 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others DEAD PF00270.29 KPA41595.1 - 1.4e-16 60.8 0.0 2.7e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA41595.1 - 1.1e-15 57.9 0.0 1.5e-14 54.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KPA41595.1 - 1.1e-12 48.4 2.3 1.1e-12 48.4 2.3 1.9 2 0 0 2 2 2 1 RecQ zinc-binding Fungal_trans PF04082.18 KPA41596.1 - 2.1e-17 63.1 2.0 3.5e-17 62.3 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41596.1 - 1.2e-06 28.5 10.0 2.7e-06 27.4 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PCI PF01399.27 KPA41598.1 - 1.7e-12 47.7 0.0 6.2e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KPA41598.1 - 0.00019 21.2 3.4 0.00043 20.0 0.3 2.3 2 1 1 3 3 3 1 26S proteasome subunit RPN7 ComR_TPR PF18710.1 KPA41598.1 - 0.023 14.3 0.1 0.043 13.4 0.1 1.4 1 0 0 1 1 1 0 ComR tetratricopeptide Tim17 PF02466.19 KPA41599.1 - 2.1e-12 47.4 1.0 3.6e-12 46.6 1.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 KPA41599.1 - 0.16 12.1 5.2 1.2 9.3 3.6 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5518) DNA_pol_B_palm PF14792.6 KPA41600.1 - 2.1e-38 131.1 0.0 4.8e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KPA41600.1 - 3.9e-25 87.8 0.3 9.5e-25 86.6 0.3 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KPA41600.1 - 7.9e-21 73.6 0.1 2.1e-20 72.3 0.1 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KPA41600.1 - 4.4e-18 65.4 0.2 1.3e-17 63.9 0.2 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 KPA41600.1 - 0.0019 18.6 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Cdd1 PF11731.8 KPA41600.1 - 0.005 17.1 0.0 2.9 8.2 0.0 3.3 1 1 2 3 3 3 1 Pathogenicity locus HHH_2 PF12826.7 KPA41600.1 - 0.0061 16.6 0.7 1.6 8.9 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix motif NTP_transf_2 PF01909.23 KPA41600.1 - 0.01 16.1 0.5 0.045 14.0 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase domain HHH_5 PF14520.6 KPA41600.1 - 0.017 15.7 0.0 1.2 9.8 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain 5_3_exonuc PF01367.20 KPA41600.1 - 0.069 13.8 0.1 2.1 9.0 0.0 2.9 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Ammonium_transp PF00909.21 KPA41601.1 - 1.4e-117 392.8 24.7 1.6e-117 392.6 24.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Filament PF00038.21 KPA41603.1 - 0.13 11.8 74.8 0.013 15.1 10.4 6.1 4 2 0 4 4 4 0 Intermediate filament protein Lip_prot_lig_C PF10437.9 KPA41603.1 - 0.53 10.3 1.8 3.5 7.7 0.2 2.9 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus DUF573 PF04504.14 KPA41603.1 - 0.61 10.8 5.6 7.4 7.3 0.0 4.8 3 2 1 4 4 4 0 Protein of unknown function, DUF573 Hemagglutinin PF00509.18 KPA41603.1 - 3 6.1 7.7 0.85 8.0 0.9 2.5 2 0 0 2 2 2 0 Haemagglutinin Med16 PF11635.8 KPA41604.1 - 1.5e-76 257.9 0.0 1.9e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 DUF3819 PF12842.7 KPA41604.1 - 0.14 12.1 0.4 0.29 11.1 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) DUF3861 PF12977.7 KPA41604.1 - 0.16 12.1 0.0 0.48 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) Sortilin-Vps10 PF15902.5 KPA41606.1 - 3.7e-279 925.8 22.2 7e-141 470.1 12.1 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KPA41606.1 - 8.2e-89 296.4 32.5 1.1e-46 159.3 11.8 3.4 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KPA41606.1 - 4.1e-11 41.2 44.1 1.3 9.3 0.1 12.9 12 0 0 12 12 12 7 BNR/Asp-box repeat BNR_6 PF15899.5 KPA41606.1 - 2.3e-05 24.0 17.5 0.36 11.0 0.0 8.8 9 0 0 9 9 9 1 BNR-Asp box repeat BNR_2 PF13088.6 KPA41606.1 - 6e-05 22.5 7.1 0.3 10.3 0.4 5.4 5 2 0 5 5 5 2 BNR repeat-like domain PSII_BNR PF14870.6 KPA41606.1 - 0.0039 16.5 2.2 1.3 8.2 0.0 4.8 5 0 0 5 5 5 1 Photosynthesis system II assembly factor YCF48 CHB_HEX_C PF03174.13 KPA41606.1 - 0.0064 16.4 3.8 2 8.5 0.1 4.9 5 0 0 5 5 5 1 Chitobiase/beta-hexosaminidase C-terminal domain DUF2561 PF10812.8 KPA41606.1 - 0.021 14.9 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) PRiA4_ORF3 PF07929.11 KPA41606.1 - 0.34 10.6 1.9 14 5.3 0.0 3.1 3 0 0 3 3 3 0 Plasmid pRiA4b ORF-3-like protein AA_permease PF00324.21 KPA41608.1 - 6.4e-140 466.9 36.3 7.7e-140 466.7 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA41608.1 - 1.8e-39 135.8 38.0 2.3e-39 135.4 38.0 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_47 PF01532.20 KPA41609.1 - 8.2e-173 575.5 0.0 9.6e-173 575.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Autophagy_act_C PF03987.15 KPA41610.1 - 2.2e-13 50.5 0.1 4.4e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.22 KPA41611.1 - 2.9e-09 36.6 0.0 6.7e-09 35.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPA41611.1 - 5e-07 29.4 0.0 7.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KPA41611.1 - 5e-05 23.2 0.0 6.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Calcipressin PF04847.12 KPA41611.1 - 0.0032 17.2 0.5 0.0062 16.3 0.0 1.8 2 1 0 2 2 2 1 Calcipressin Limkain-b1 PF11608.8 KPA41611.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 KPA41611.1 - 0.044 13.6 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif WD40 PF00400.32 KPA41612.1 - 4.5e-17 62.1 13.4 0.00055 20.7 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA41612.1 - 5.5e-08 33.0 0.0 0.0069 16.7 0.0 4.3 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ribonuc_L-PSP PF01042.21 KPA41613.1 - 1.9e-41 140.8 0.2 3.2e-41 140.1 0.2 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP AIRS_C PF02769.22 KPA41613.1 - 0.097 12.8 0.0 0.17 12.0 0.0 1.3 1 1 0 1 1 1 0 AIR synthase related protein, C-terminal domain ERK-JNK_inhib PF15002.6 KPA41613.1 - 0.16 11.6 0.0 2.9 7.6 0.0 2.4 2 1 1 3 3 3 0 ERK and JNK pathways, inhibitor PMT PF02366.18 KPA41614.1 - 7.2e-84 281.2 17.4 1.3e-83 280.4 17.4 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KPA41614.1 - 1.7e-70 236.7 6.7 1.7e-70 236.7 6.7 2.9 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KPA41614.1 - 1.5e-21 77.1 0.6 3.2e-21 76.0 0.3 1.6 1 1 1 2 2 2 2 MIR domain CAP59_mtransfer PF11735.8 KPA41615.1 - 2.6e-86 289.2 0.0 3.3e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 zf-C2H2 PF00096.26 KPA41618.1 - 0.0079 16.6 2.7 0.0079 16.6 2.7 3.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type Asn_synthase PF00733.21 KPA41619.1 - 1.4e-17 64.4 1.3 7.4e-09 35.7 0.1 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KPA41619.1 - 4.1e-08 33.2 0.0 1e-06 28.7 0.0 2.9 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KPA41619.1 - 0.00023 21.4 0.0 0.00068 19.8 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 KPA41619.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 NAD synthase PHD PF00628.29 KPA41623.1 - 9.2e-07 28.7 5.6 1.5e-06 27.9 5.6 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KPA41623.1 - 0.08 12.9 3.3 0.18 11.8 3.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 KPA41623.1 - 1.3 8.9 8.8 0.067 13.1 3.4 1.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KPA41623.1 - 1.9 8.1 9.2 0.22 11.1 2.0 2.5 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KPA41623.1 - 1.9 8.1 9.6 0.8 9.3 4.9 2.4 2 1 0 2 2 2 0 PHD-finger DUF3716 PF12511.8 KPA41623.1 - 2.5 8.2 7.7 6.5 6.9 7.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) CoA_transf_3 PF02515.17 KPA41624.1 - 4.1e-129 430.9 0.0 4.7e-129 430.7 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Glycos_transf_3 PF00591.21 KPA41625.1 - 2.7e-62 210.7 0.0 5.5e-62 209.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KPA41625.1 - 6.3e-14 51.6 0.2 1.6e-13 50.2 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain adh_short PF00106.25 KPA41626.1 - 3.3e-46 157.2 0.0 4.3e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA41626.1 - 2.5e-31 109.0 0.0 3.3e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KPA41626.1 - 3.1e-05 23.6 0.1 0.0037 16.9 0.1 2.1 2 0 0 2 2 2 2 NmrA-like family DUF1776 PF08643.10 KPA41626.1 - 5.1e-05 22.8 0.0 7.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KPA41626.1 - 0.00054 19.5 0.0 0.0011 18.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RNase_H2_suC PF08615.11 KPA41627.1 - 3.6e-26 92.0 0.0 4.5e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNase_T PF00929.24 KPA41628.1 - 3.6e-20 73.2 0.0 5.9e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KPA41628.1 - 0.003 17.3 0.0 0.0097 15.6 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease MOZ_SAS PF01853.18 KPA41629.1 - 8.2e-81 269.9 0.1 1.1e-80 269.5 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KPA41629.1 - 3.3e-22 77.9 1.2 6.1e-22 77.0 1.2 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KPA41629.1 - 3.3e-17 62.1 0.3 8.3e-17 60.8 0.0 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KPA41629.1 - 0.0012 19.2 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA41629.1 - 0.011 15.9 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DDRGK PF09756.9 KPA41629.1 - 0.85 9.2 0.0 0.85 9.2 0.0 2.7 3 0 0 3 3 3 0 DDRGK domain Glyco_hydro_125 PF06824.11 KPA41630.1 - 3e-179 596.3 0.0 3.5e-179 596.1 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Aminotran_1_2 PF00155.21 KPA41631.1 - 2.4e-26 92.8 0.0 5.8e-26 91.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KPA41631.1 - 0.00025 20.0 0.0 0.032 13.0 0.0 2.7 2 1 0 2 2 2 2 Alanine-glyoxylate amino-transferase CDC27 PF09507.10 KPA41632.1 - 2.4e-87 294.1 34.9 3.2e-87 293.7 34.9 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF5072 PF16807.5 KPA41632.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5072) zf-C3HC4_2 PF13923.6 KPA41633.1 - 1.1e-13 50.8 15.8 1.1e-12 47.6 9.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA41633.1 - 6.1e-09 35.6 9.6 6.1e-09 35.6 9.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA41633.1 - 3.8e-08 33.2 13.9 4.6e-08 32.9 7.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KPA41633.1 - 9.3e-08 31.8 13.4 1.5e-07 31.1 7.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPA41633.1 - 4.3e-07 29.8 11.8 6.3e-07 29.3 9.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KPA41633.1 - 6e-07 29.2 10.3 6.4e-05 22.7 7.9 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KPA41633.1 - 2.3e-06 27.7 12.8 3.6e-06 27.0 9.0 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KPA41633.1 - 3.8e-06 27.1 9.4 3.8e-06 27.1 9.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 KPA41633.1 - 1.3e-05 25.0 2.5 1.3e-05 25.0 2.5 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein U-box PF04564.15 KPA41633.1 - 1.6e-05 25.0 0.0 0.00015 21.9 0.0 2.3 2 0 0 2 2 2 1 U-box domain zf-rbx1 PF12678.7 KPA41633.1 - 2.3e-05 24.6 3.4 2.3e-05 24.6 3.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KPA41633.1 - 0.00072 19.6 4.0 0.00072 19.6 4.0 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 Mob_synth_C PF06463.13 KPA41633.1 - 0.0014 18.5 2.9 0.0038 17.2 2.9 1.7 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-RING_4 PF14570.6 KPA41633.1 - 0.0025 17.6 2.5 0.0025 17.6 2.5 2.5 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain SAP PF02037.27 KPA41633.1 - 0.0064 16.2 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 SAP domain DUF3762 PF12591.8 KPA41633.1 - 0.026 14.8 0.7 16 5.9 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3762) Rad50_zn_hook PF04423.14 KPA41633.1 - 0.17 11.8 1.1 4.6 7.2 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Di19 PF05605.12 KPA41633.1 - 0.8 10.0 7.4 0.95 9.8 0.1 2.9 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-P11 PF03854.14 KPA41633.1 - 0.88 9.3 9.8 0.074 12.7 4.9 1.7 2 0 0 2 2 1 0 P-11 zinc finger zf-WRNIP1_ubi PF18279.1 KPA41633.1 - 1 10.2 4.7 0.91 10.3 0.2 2.9 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-ANAPC11 PF12861.7 KPA41633.1 - 1.1 9.4 6.4 0.094 12.8 1.6 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Snf7 PF03357.21 KPA41634.1 - 1.7e-18 66.8 23.7 3.5e-18 65.8 23.7 1.6 1 0 0 1 1 1 1 Snf7 BUD22 PF09073.10 KPA41634.1 - 0.67 9.2 21.5 0.97 8.7 21.5 1.1 1 0 0 1 1 1 0 BUD22 CorA PF01544.18 KPA41634.1 - 1.1 8.5 7.2 0.19 11.0 2.5 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein adh_short PF00106.25 KPA41635.1 - 2e-52 177.5 0.0 2.6e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA41635.1 - 1.9e-36 125.8 0.0 2.9e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA41635.1 - 6.7e-12 45.7 0.0 9.4e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA41635.1 - 0.032 13.4 0.1 0.077 12.1 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Pribosyltran_N PF13793.6 KPA41636.1 - 7.8e-42 141.9 0.0 6.5e-41 138.9 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KPA41636.1 - 6.5e-35 120.8 0.1 2e-29 103.0 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KPA41636.1 - 3.6e-09 36.3 0.1 1.4e-06 27.9 0.1 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain XPG_I_2 PF12813.7 KPA41637.1 - 1.5e-47 162.2 0.0 2.2e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 KPA41637.1 - 0.22 11.9 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 XPG I-region PAP_assoc PF03828.19 KPA41638.1 - 6.8e-17 61.4 0.1 8.5e-15 54.7 0.1 2.7 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KPA41638.1 - 0.0027 18.0 0.0 0.0074 16.6 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain TFIIF_alpha PF05793.12 KPA41639.1 - 0.0048 15.5 57.8 0.041 12.5 57.5 2.4 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.9 KPA41640.1 - 1.7e-51 174.5 11.9 1.7e-51 174.5 11.9 2.7 1 1 1 2 2 2 1 Pre-mRNA-splicing factor of RES complex TRAPPC-Trs85 PF12739.7 KPA41641.1 - 1.3e-114 383.4 0.2 3.2e-114 382.1 0.2 1.6 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit MFS_1 PF07690.16 KPA41642.1 - 9e-38 130.1 45.5 5.6e-37 127.5 45.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA41642.1 - 4.8e-11 42.2 14.2 4.8e-11 42.2 14.2 2.7 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPA41642.1 - 2.5e-09 36.1 12.5 3.2e-09 35.8 12.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 KPA41642.1 - 0.09 11.0 9.3 0.016 13.5 2.8 2.2 1 1 0 2 2 2 0 BT1 family ThiF PF00899.21 KPA41643.1 - 5.6e-21 75.0 0.0 1.5e-20 73.6 0.0 1.7 1 1 0 1 1 1 1 ThiF family zf-RING_5 PF14634.6 KPA41644.1 - 2.8e-08 33.6 6.7 4.6e-08 32.9 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KPA41644.1 - 0.00011 22.5 3.8 0.0002 21.6 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KPA41644.1 - 0.00039 20.2 3.1 0.00077 19.3 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA41644.1 - 0.0012 18.8 1.2 0.0028 17.7 0.4 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KPA41644.1 - 0.0014 18.4 2.5 0.0033 17.2 2.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPA41644.1 - 0.002 17.9 6.3 0.0037 17.1 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPA41644.1 - 0.0032 17.3 2.7 0.0064 16.3 2.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Mito_carr PF00153.27 KPA41644.1 - 0.065 13.2 0.1 0.18 11.8 0.0 1.8 2 0 0 2 2 1 0 Mitochondrial carrier protein zf-C3HC4_4 PF15227.6 KPA41644.1 - 0.086 13.0 1.3 0.19 11.9 1.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF948 PF06103.11 KPA41644.1 - 0.094 13.0 0.2 0.2 12.0 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 KPA41644.1 - 0.27 11.9 1.8 0.93 10.2 1.8 1.9 1 0 0 1 1 1 0 Initiation control protein YabA Spc24 PF08286.11 KPA41644.1 - 0.4 11.0 4.3 0.14 12.4 0.9 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 zf-rbx1 PF12678.7 KPA41644.1 - 1.4 9.3 4.0 2.9 8.3 4.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain DZR PF12773.7 KPA41644.1 - 1.8 8.6 5.6 3.7 7.7 5.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KPA41644.1 - 2.5 8.2 5.4 4.5 7.3 5.4 1.4 1 0 0 1 1 1 0 zinc-ribbons GDA1_CD39 PF01150.17 KPA41645.1 - 1.2e-110 370.1 0.0 1.5e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF775 PF05603.12 KPA41646.1 - 2e-56 190.7 0.3 4.1e-56 189.7 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF775) DUF4743 PF15916.5 KPA41647.1 - 9e-12 45.0 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KPA41647.1 - 2.3e-08 34.2 0.1 8.2e-08 32.4 0.0 2.0 2 1 1 3 3 3 1 NUDIX domain RNA_pol_Rpb8 PF03870.15 KPA41648.1 - 5.1e-44 149.8 0.0 5.7e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KPA41648.1 - 0.00011 22.3 0.0 0.0022 18.1 0.0 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase, subunit G PAXNEB PF05625.11 KPA41649.1 - 2e-105 353.0 0.0 2.3e-105 352.8 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 KPA41650.1 - 5.5e-11 42.4 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain NST1 PF13945.6 KPA41652.1 - 6.8e-47 160.1 17.7 6.8e-47 160.1 17.7 4.8 2 2 1 3 3 3 1 Salt tolerance down-regulator Ras PF00071.22 KPA41653.1 - 2.5e-50 170.3 0.0 2.9e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA41653.1 - 3.2e-22 79.0 0.0 4.4e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA41653.1 - 3.5e-06 26.6 0.0 5.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KPA41653.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KPA41653.1 - 0.045 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPA41653.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KPA41653.1 - 0.11 12.3 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KPA41653.1 - 0.21 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MRP-L28 PF09812.9 KPA41654.1 - 0.00027 21.1 0.6 0.0004 20.6 0.3 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L28 SpoIISB_antitox PF14185.6 KPA41655.1 - 0.18 11.7 0.0 0.57 10.1 0.0 1.8 2 0 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system Tho1_MOS11_C PF18592.1 KPA41656.1 - 0.14 12.0 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain Transketolase_N PF00456.21 KPA41657.1 - 7.2e-126 419.7 0.0 1.3e-125 418.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KPA41657.1 - 3.3e-37 127.9 0.0 8.1e-37 126.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 KPA41657.1 - 8.3e-08 31.8 0.0 1.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KPA41657.1 - 8.2e-07 28.3 0.1 1.5e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.20 KPA41657.1 - 1.3e-06 28.3 0.0 3.6e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 KPA41657.1 - 0.00037 20.3 1.5 0.048 13.5 1.6 3.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PepSY_2 PF13670.6 KPA41657.1 - 0.014 15.4 0.0 0.043 13.8 0.0 1.8 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain adh_short_C2 PF13561.6 KPA41658.1 - 2.6e-54 184.2 0.4 3.6e-54 183.8 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA41658.1 - 7.5e-42 143.0 0.8 9.1e-42 142.7 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA41658.1 - 1.3e-11 44.8 0.4 1.8e-11 44.3 0.4 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KPA41658.1 - 0.041 12.9 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPA41658.1 - 0.051 13.0 0.4 0.28 10.6 0.4 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADP_ribosyl_GH PF03747.14 KPA41659.1 - 2.9e-61 207.7 0.0 4.2e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Rick_17kDa_Anti PF05433.15 KPA41659.1 - 0.014 15.2 1.0 1.3 8.9 0.2 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 KPA41659.1 - 0.12 12.1 0.2 20 5.0 0.0 2.6 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KPA41659.1 - 3.1 7.9 6.2 9.9 6.3 0.0 2.9 4 0 0 4 4 4 0 Glycine zipper Sugar_tr PF00083.24 KPA41660.1 - 1.2e-111 373.7 24.4 1.4e-111 373.6 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA41660.1 - 3.9e-30 105.0 57.7 1.9e-25 89.5 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FA_desaturase PF00487.24 KPA41660.1 - 1.3 8.8 5.8 3.7 7.3 5.8 1.8 1 0 0 1 1 1 0 Fatty acid desaturase Fungal_trans_2 PF11951.8 KPA41661.1 - 5.3e-18 65.0 2.5 1.4e-17 63.6 2.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41661.1 - 2.1e-07 30.9 14.1 4.4e-07 29.9 14.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vpu PF00558.19 KPA41662.1 - 0.2 11.4 0.3 0.47 10.3 0.3 1.5 1 0 0 1 1 1 0 Vpu protein DPBB_1 PF03330.18 KPA41663.1 - 0.0011 19.2 0.3 0.0026 18.0 0.0 1.7 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 KPA41663.1 - 0.0022 18.0 0.2 0.0047 16.9 0.2 1.5 1 0 0 1 1 1 1 Pollen allergen Sulfotransfer_4 PF17784.1 KPA41664.1 - 4.1e-65 219.6 0.0 5.3e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Chromo PF00385.24 KPA41665.1 - 3.3e-10 39.7 4.8 3.9e-07 29.9 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Ank PF00023.30 KPA41665.1 - 5.3e-10 39.3 0.0 0.00011 22.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat NACHT PF05729.12 KPA41665.1 - 4.4e-08 33.2 0.1 1.2e-07 31.8 0.1 1.8 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 KPA41665.1 - 8.2e-07 29.5 0.0 0.0016 19.0 0.0 4.7 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA41665.1 - 1.6e-06 28.5 0.0 0.00026 21.5 0.0 3.2 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA41665.1 - 0.00056 20.2 0.2 3.7 8.4 0.0 5.4 5 1 0 5 5 5 1 Ankyrin repeat AAA_16 PF13191.6 KPA41665.1 - 0.0029 18.0 0.0 0.018 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KPA41665.1 - 0.0032 17.9 0.0 2.9 8.3 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA41665.1 - 0.012 15.9 0.0 0.055 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ank_5 PF13857.6 KPA41665.1 - 0.036 14.4 0.0 0.43 11.0 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeats (many copies) RNA_helicase PF00910.22 KPA41665.1 - 0.18 12.2 0.2 2.8 8.4 0.0 2.6 3 0 0 3 3 3 0 RNA helicase Nodulin_late PF07127.11 KPA41666.1 - 0.0085 16.4 1.5 0.013 15.8 1.5 1.3 1 0 0 1 1 1 1 Late nodulin protein PIG-P PF08510.12 KPA41667.1 - 0.04 13.8 0.4 0.59 10.1 0.3 2.3 2 0 0 2 2 2 0 PIG-P Peptidase_U4 PF03419.13 KPA41667.1 - 0.066 12.5 1.5 0.12 11.6 1.5 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA NmrA PF05368.13 KPA41668.1 - 3.4e-14 53.0 0.0 4.5e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA41668.1 - 9.8e-13 48.4 0.0 1.5e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HET PF06985.11 KPA41669.1 - 2.4e-26 92.9 0.0 5.1e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KPA41670.1 - 7.9e-39 133.6 77.0 7e-31 107.4 41.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA41670.1 - 8.8e-12 44.6 34.9 6.4e-07 28.6 11.2 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter CoA_binding PF02629.19 KPA41671.1 - 1.6e-27 96.0 2.7 2.8e-27 95.2 0.4 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KPA41671.1 - 2.2e-24 86.0 0.4 3.8e-24 85.3 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KPA41671.1 - 8.7e-11 41.8 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KPA41671.1 - 0.00056 20.4 0.1 0.0015 19.0 0.0 1.8 2 0 0 2 2 2 1 CoA binding domain UQ_con PF00179.26 KPA41672.1 - 1.2e-40 138.4 0.0 1.5e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KPA41672.1 - 2.1e-06 27.4 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KPA41672.1 - 3.6e-06 26.7 0.0 5.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF1421 PF07223.11 KPA41672.1 - 0.037 13.9 0.2 0.12 12.2 0.1 1.9 1 1 1 2 2 2 0 UBA-like domain (DUF1421) UEV PF05743.13 KPA41672.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain AAA PF00004.29 KPA41673.1 - 2.1e-41 141.5 0.0 3.7e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KPA41673.1 - 1e-11 44.6 0.3 2.2e-11 43.5 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KPA41673.1 - 5e-11 42.2 0.4 1e-10 41.3 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KPA41673.1 - 4.4e-06 26.9 0.0 9.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KPA41673.1 - 8.1e-06 26.2 0.1 0.0065 16.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KPA41673.1 - 1.5e-05 24.3 0.0 2.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KPA41673.1 - 8.6e-05 22.6 0.1 0.00036 20.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPA41673.1 - 0.00036 20.9 0.1 0.0065 16.9 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KPA41673.1 - 0.00048 19.9 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 KPA41673.1 - 0.0015 18.1 0.3 0.011 15.3 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 KPA41673.1 - 0.0019 18.7 0.0 0.0044 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KPA41673.1 - 0.0053 17.0 1.2 0.0094 16.2 0.0 2.0 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KPA41673.1 - 0.01 16.0 0.1 0.028 14.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 KPA41673.1 - 0.017 14.9 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 KPA41673.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KPA41673.1 - 0.024 13.8 0.0 0.055 12.7 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KPA41673.1 - 0.029 14.4 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPA41673.1 - 0.056 13.8 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KPA41673.1 - 0.06 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KPA41673.1 - 0.065 12.7 1.3 0.51 9.8 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 KPA41673.1 - 0.068 13.1 0.1 0.62 10.0 0.1 2.3 1 1 1 2 2 2 0 NACHT domain WYL PF13280.6 KPA41673.1 - 0.068 13.2 0.1 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 WYL domain ATPase PF06745.13 KPA41673.1 - 0.08 12.3 0.0 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 KPA41673.1 - 0.094 12.0 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KPA41673.1 - 0.11 12.2 0.4 0.33 10.6 0.4 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KPA41673.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KPA41673.1 - 1.1 8.8 5.4 0.58 9.7 0.4 2.7 2 1 0 3 3 3 0 AAA domain Promethin PF16015.5 KPA41674.1 - 4.2e-36 123.1 16.0 4.9e-36 122.9 16.0 1.1 1 0 0 1 1 1 1 Promethin VIT1 PF01988.19 KPA41674.1 - 0.12 12.2 4.9 0.14 12.0 4.9 1.2 1 0 0 1 1 1 0 VIT family Wzy_C PF04932.15 KPA41674.1 - 4.4 6.9 9.4 6.6 6.4 9.4 1.3 1 0 0 1 1 1 0 O-Antigen ligase SNF2_N PF00176.23 KPA41675.1 - 5e-66 222.8 0.9 1.2e-65 221.6 0.9 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KPA41675.1 - 3.1e-48 163.5 17.0 3.1e-48 163.5 17.0 5.5 4 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 KPA41675.1 - 2.6e-20 72.8 0.0 6.5e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA41675.1 - 1.6e-07 31.5 0.0 1.6e-07 31.5 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPA41675.1 - 0.002 17.9 0.0 0.0059 16.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Fe_hyd_lg_C PF02906.14 KPA41675.1 - 0.23 11.1 2.7 0.25 11.0 1.0 1.9 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain ABC_tran PF00005.27 KPA41676.1 - 6.4e-46 156.3 0.0 6.1e-22 78.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KPA41676.1 - 1.3e-21 76.4 3.6 4.3e-21 74.7 2.6 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KPA41676.1 - 1.2e-18 68.0 0.3 0.00014 21.8 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPA41676.1 - 7.4e-11 41.9 0.5 0.00072 19.1 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPA41676.1 - 5.6e-09 36.8 0.8 0.038 14.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KPA41676.1 - 2.3e-08 33.7 0.0 0.0025 17.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KPA41676.1 - 6.6e-07 29.9 0.1 0.0011 19.4 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KPA41676.1 - 2.7e-06 27.3 0.8 0.055 13.2 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 KPA41676.1 - 3.9e-06 27.2 0.0 0.0016 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPA41676.1 - 2e-05 24.9 0.0 0.1 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KPA41676.1 - 2e-05 24.6 0.0 0.028 14.5 0.0 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA41676.1 - 2.2e-05 24.4 0.1 0.012 15.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KPA41676.1 - 6.1e-05 23.6 0.0 0.095 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KPA41676.1 - 0.00019 21.1 0.0 0.052 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KPA41676.1 - 0.00022 21.7 0.0 1.6 9.1 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KPA41676.1 - 0.00027 20.9 0.8 0.29 11.0 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 KPA41676.1 - 0.00035 20.8 0.2 0.22 11.7 0.1 2.9 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 KPA41676.1 - 0.00035 20.6 0.1 1.2 9.1 0.2 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KPA41676.1 - 0.00052 20.4 0.6 1.7 9.1 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_24 PF13479.6 KPA41676.1 - 0.00072 19.3 2.2 2 8.1 0.0 3.7 4 0 0 4 4 4 1 AAA domain Dynamin_N PF00350.23 KPA41676.1 - 0.0019 18.3 0.0 2.1 8.4 0.0 3.2 3 0 0 3 3 3 1 Dynamin family AAA_14 PF13173.6 KPA41676.1 - 0.0043 17.1 0.0 3.6 7.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KPA41676.1 - 0.013 15.7 0.1 3.9 7.7 0.1 3.1 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KPA41676.1 - 0.015 14.8 0.0 0.88 9.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KPA41676.1 - 0.02 14.8 0.0 0.84 9.5 0.0 2.5 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KPA41676.1 - 0.026 13.7 0.0 6.7 5.8 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_7 PF12775.7 KPA41676.1 - 0.042 13.4 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KPA41676.1 - 0.051 13.3 0.7 2.5 7.8 0.0 3.0 4 0 0 4 4 2 0 AAA domain MCM PF00493.23 KPA41676.1 - 0.077 12.1 0.0 11 5.0 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain TsaE PF02367.17 KPA41676.1 - 0.099 12.6 0.5 29 4.7 0.0 3.0 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 KPA41676.1 - 0.11 12.6 0.5 24 4.9 0.0 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain DUF2813 PF11398.8 KPA41676.1 - 0.12 11.6 0.2 15 4.7 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF2813) AAA_17 PF13207.6 KPA41676.1 - 0.12 12.8 0.0 19 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dicty_REP PF05086.12 KPA41677.1 - 1.9 6.4 8.6 2.3 6.1 8.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pneumo_att_G PF05539.11 KPA41677.1 - 2.8 7.5 16.1 3.4 7.2 16.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Glyco_hydro_72 PF03198.14 KPA41678.1 - 4.4e-121 404.0 5.9 7.2e-121 403.3 5.9 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KPA41678.1 - 7.2e-23 81.1 7.1 8.3e-23 80.9 5.5 2.1 2 0 0 2 2 2 1 X8 domain Glyco_hydro_2_C PF02836.17 KPA41678.1 - 2.8e-05 23.4 1.2 0.00015 21.0 1.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 KPA41678.1 - 0.015 14.7 0.2 0.59 9.5 0.2 2.3 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Peptidase_S41 PF03572.18 KPA41679.1 - 4.6e-06 26.3 0.0 1.1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 Bromodomain PF00439.25 KPA41679.1 - 0.01 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 0 Bromodomain PAP2 PF01569.21 KPA41681.1 - 1.1e-22 80.3 5.4 1.1e-22 80.3 5.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KPA41681.1 - 0.058 13.1 11.0 0.015 15.0 6.7 2.1 2 1 0 2 2 2 0 PAP2 superfamily Ysc84 PF04366.12 KPA41682.1 - 1e-47 161.1 0.1 1.7e-47 160.3 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator PRP38_assoc PF12871.7 KPA41683.1 - 0.0058 17.2 1.1 0.011 16.3 1.1 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term FliT PF05400.13 KPA41683.1 - 0.28 12.0 2.0 2.6 8.9 1.2 2.4 1 1 1 2 2 2 0 Flagellar protein FliT MBOAT PF03062.19 KPA41684.1 - 1.5e-34 119.9 13.8 3.5e-33 115.4 9.1 2.3 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family NESP55 PF06390.12 KPA41684.1 - 1.9 8.0 9.7 6.4 6.3 0.0 2.8 3 0 0 3 3 3 0 Neuroendocrine-specific golgi protein P55 (NESP55) COesterase PF00135.28 KPA41685.1 - 1e-80 272.1 0.0 9.9e-71 239.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA41685.1 - 4.2e-08 33.3 0.0 1.2e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold HSP90 PF00183.18 KPA41686.1 - 1.1e-221 737.2 27.5 1.1e-221 737.2 27.5 1.3 2 0 0 2 2 2 1 Hsp90 protein Flavin_Reduct PF01613.18 KPA41686.1 - 2.3e-34 118.7 0.0 6.6e-34 117.2 0.0 1.8 1 0 0 1 1 1 1 Flavin reductase like domain HATPase_c PF02518.26 KPA41686.1 - 5.4e-16 59.1 0.1 1.1e-15 58.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KPA41686.1 - 5.2e-10 39.3 0.1 1.4e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 KPA41686.1 - 0.097 12.7 0.3 0.28 11.2 0.3 1.7 1 0 0 1 1 1 0 Tumour suppressor protein DUF1676 PF07898.13 KPA41686.1 - 0.23 11.5 4.5 0.76 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Oest_recep PF02159.15 KPA41687.1 - 5.9 7.4 8.5 0.32 11.5 1.4 2.3 2 2 0 2 2 2 0 Oestrogen receptor Vps5 PF09325.10 KPA41688.1 - 1.3e-87 293.3 4.0 1.3e-87 293.3 4.0 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KPA41688.1 - 1.3e-24 86.3 0.2 3.2e-24 85.1 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 KPA41688.1 - 0.0015 18.3 6.8 0.031 14.0 2.4 2.6 1 1 1 2 2 2 1 BAR domain of APPL family BAR_2 PF10455.9 KPA41688.1 - 0.0018 17.4 1.0 0.0027 16.9 1.0 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3_WASP_bdg PF10456.9 KPA41688.1 - 0.015 14.8 0.8 0.24 10.8 0.1 2.1 1 1 1 2 2 2 0 WASP-binding domain of Sorting nexin protein DUF713 PF05218.14 KPA41688.1 - 0.11 12.2 3.3 0.15 11.8 2.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF713) TFIID_NTD2 PF04494.15 KPA41689.1 - 2.6e-41 140.9 0.0 3.6e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 KPA41689.1 - 2.8e-35 119.7 13.9 1.5e-07 32.0 0.3 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA41689.1 - 7.3e-12 45.4 0.0 0.14 12.5 0.0 5.3 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KPA41689.1 - 1.9e-07 30.8 0.0 4.4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 KPA41689.1 - 0.0037 16.3 0.1 4.7 6.1 0.0 3.7 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KPA41689.1 - 0.0082 14.9 0.0 11 4.7 0.0 3.7 3 1 1 4 4 4 1 Nup133 N terminal like Nup160 PF11715.8 KPA41689.1 - 0.013 14.2 0.0 8.7 4.9 0.0 3.3 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Med11 PF10280.9 KPA41690.1 - 5.6e-43 146.7 0.0 6.5e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein MDMPI_N PF11716.8 KPA41690.1 - 0.094 13.4 0.1 0.14 12.9 0.1 1.3 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Ytp1 PF10355.9 KPA41691.1 - 1.2e-43 149.3 18.5 6.1e-32 110.9 4.9 2.4 1 1 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KPA41691.1 - 2.6e-30 104.3 1.5 2.6e-30 104.3 1.5 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KPA41691.1 - 0.00085 19.5 7.5 0.00085 19.5 7.5 3.1 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Cytochrom_B558a PF05038.13 KPA41693.1 - 0.017 14.7 0.1 0.017 14.7 0.1 1.1 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit bZIP_2 PF07716.15 KPA41695.1 - 0.0047 17.0 2.1 0.0091 16.1 2.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper IFP_35_N PF07334.13 KPA41695.1 - 0.052 13.6 0.3 0.052 13.6 0.3 2.2 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DivIC PF04977.15 KPA41695.1 - 0.059 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Mto2_bdg PF12808.7 KPA41695.1 - 0.13 12.6 0.6 0.29 11.5 0.6 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FOXP-CC PF16159.5 KPA41695.1 - 0.81 10.4 6.7 0.82 10.3 0.1 3.8 4 0 0 4 4 4 0 FOXP coiled-coil domain YdjO PF14169.6 KPA41695.1 - 5.6 6.8 13.0 3.7 7.4 0.1 4.6 5 0 0 5 5 5 0 Cold-inducible protein YdjO Glyco_hydro_4 PF02056.16 KPA41696.1 - 0.21 11.1 1.8 8.5 5.9 0.3 2.2 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase HET PF06985.11 KPA41697.1 - 3.8e-12 46.8 7.0 7.1e-10 39.4 1.1 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA PF00004.29 KPA41699.1 - 2.7e-45 154.0 0.3 1e-44 152.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KPA41699.1 - 1e-09 38.2 0.1 5.6e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KPA41699.1 - 7.2e-09 35.8 0.3 2.6e-08 34.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KPA41699.1 - 5.8e-08 33.0 0.0 1.2e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KPA41699.1 - 1.7e-07 31.8 0.5 3.7e-05 24.2 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KPA41699.1 - 3.1e-06 26.6 0.0 6.5e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KPA41699.1 - 3.2e-05 24.2 0.9 0.0097 16.2 0.1 2.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KPA41699.1 - 0.00022 21.0 0.0 0.00069 19.4 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KPA41699.1 - 0.00059 20.4 0.0 0.0016 19.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KPA41699.1 - 0.0007 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KPA41699.1 - 0.0007 19.2 0.1 0.0025 17.3 0.1 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_3 PF17862.1 KPA41699.1 - 0.00083 19.1 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 KPA41699.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KPA41699.1 - 0.0014 18.6 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KPA41699.1 - 0.0015 18.5 0.1 0.0065 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KPA41699.1 - 0.0019 18.6 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 KPA41699.1 - 0.0021 18.0 0.0 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 KPA41699.1 - 0.0049 16.6 0.6 0.014 15.1 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KPA41699.1 - 0.0056 16.5 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KPA41699.1 - 0.0065 15.9 0.1 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KPA41699.1 - 0.0067 16.4 0.1 0.11 12.4 0.0 2.6 3 0 0 3 3 2 1 NACHT domain AAA_33 PF13671.6 KPA41699.1 - 0.008 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KPA41699.1 - 0.01 15.3 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Viral_Hsp90 PF03225.14 KPA41699.1 - 0.011 14.3 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue IstB_IS21 PF01695.17 KPA41699.1 - 0.012 15.4 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AFG1_ATPase PF03969.16 KPA41699.1 - 0.02 13.8 0.0 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 AFG1-like ATPase AAA_24 PF13479.6 KPA41699.1 - 0.022 14.5 0.2 0.054 13.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KPA41699.1 - 0.028 14.3 0.7 0.34 10.8 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KPA41699.1 - 0.029 13.7 1.1 0.56 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 KPA41699.1 - 0.034 13.9 0.1 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KPA41699.1 - 0.042 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_23 PF13476.6 KPA41699.1 - 0.055 14.0 0.1 6.3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KPA41699.1 - 0.067 12.9 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KPA41699.1 - 0.075 12.6 2.0 0.27 10.8 0.1 2.4 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KPA41699.1 - 0.082 12.2 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 KPA41699.1 - 0.11 12.8 0.1 0.37 11.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KPA41699.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KPA41699.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KPA41699.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Folliculin PF11704.8 KPA41700.1 - 8.4e-59 198.6 0.0 2.3e-58 197.1 0.0 1.7 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport AAA PF00004.29 KPA41701.1 - 4.1e-32 111.4 0.0 4.7e-14 53.0 0.0 3.6 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 KPA41701.1 - 2e-17 63.1 0.2 4.3e-14 52.5 0.1 3.3 4 0 0 4 4 2 1 AAA lid domain AAA_22 PF13401.6 KPA41701.1 - 9.3e-13 48.6 2.4 0.44 10.8 0.1 6.7 4 2 0 4 4 4 3 AAA domain AAA_5 PF07728.14 KPA41701.1 - 7.9e-11 42.1 0.0 0.039 13.9 0.0 3.8 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KPA41701.1 - 1.7e-09 37.7 0.0 0.0042 16.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 KPA41701.1 - 3.9e-08 33.2 0.0 0.3 10.8 0.0 4.2 3 2 0 3 3 3 3 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KPA41701.1 - 3e-07 30.7 0.3 0.11 12.6 0.0 3.6 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 KPA41701.1 - 1.3e-06 28.0 0.1 0.89 8.9 0.0 3.6 3 0 0 3 3 3 3 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KPA41701.1 - 2e-06 28.2 1.3 0.52 10.5 0.0 4.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KPA41701.1 - 3.4e-06 27.5 0.7 1.9 8.8 0.2 4.5 3 1 1 4 4 4 1 AAA domain RNA_helicase PF00910.22 KPA41701.1 - 3.6e-06 27.3 0.3 0.44 11.0 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 KPA41701.1 - 7.7e-06 26.5 3.9 0.19 12.2 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KPA41701.1 - 9.5e-06 26.1 3.3 2.5 8.5 0.0 4.9 3 2 1 4 4 4 2 AAA ATPase domain IstB_IS21 PF01695.17 KPA41701.1 - 1.2e-05 25.1 0.0 0.056 13.2 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_24 PF13479.6 KPA41701.1 - 2.5e-05 24.1 2.6 0.63 9.7 0.0 3.8 4 1 0 4 4 3 2 AAA domain AAA_7 PF12775.7 KPA41701.1 - 6.1e-05 22.6 0.8 0.73 9.3 0.1 3.8 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_17 PF13207.6 KPA41701.1 - 8.6e-05 23.0 1.1 0.041 14.3 0.0 3.7 3 1 0 3 3 2 1 AAA domain Torsin PF06309.11 KPA41701.1 - 0.0003 20.9 0.0 3.8 7.6 0.0 3.4 3 0 0 3 3 3 1 Torsin AAA_11 PF13086.6 KPA41701.1 - 0.00061 19.6 0.0 0.93 9.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain TniB PF05621.11 KPA41701.1 - 0.00069 19.1 0.0 13 5.1 0.0 4.4 4 0 0 4 4 4 0 Bacterial TniB protein ResIII PF04851.15 KPA41701.1 - 0.00097 19.2 0.0 23 4.9 0.0 4.8 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 KPA41701.1 - 0.0011 18.7 0.3 1.8 8.3 0.0 4.2 3 2 0 3 3 3 1 Sigma-54 interaction domain PhoH PF02562.16 KPA41701.1 - 0.0018 17.7 0.1 1.3 8.4 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein SRP54 PF00448.22 KPA41701.1 - 0.0028 17.3 0.3 1.3 8.6 0.0 3.7 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.6 KPA41701.1 - 0.0046 17.1 0.1 21 5.2 0.0 4.0 4 0 0 4 4 3 0 Sigma-54 interaction domain TsaE PF02367.17 KPA41701.1 - 0.0054 16.7 0.1 1.5 8.9 0.1 3.2 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KPA41701.1 - 0.0088 15.8 0.1 3.5 7.3 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase VirE PF05272.11 KPA41701.1 - 0.037 13.8 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Virulence-associated protein E ABC_tran PF00005.27 KPA41701.1 - 0.055 14.0 0.5 9.2 6.8 0.0 3.3 3 0 0 3 3 3 0 ABC transporter CARMIL_C PF16000.5 KPA41701.1 - 0.08 12.6 0.3 3.4 7.2 0.1 2.2 2 0 0 2 2 2 0 CARMIL C-terminus AAA_2 PF07724.14 KPA41701.1 - 0.089 12.9 0.6 53 3.9 0.0 4.0 4 0 0 4 4 4 0 AAA domain (Cdc48 subfamily) AAA_6 PF12774.7 KPA41701.1 - 0.13 11.2 0.1 7.8 5.4 0.0 2.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region NACHT PF05729.12 KPA41701.1 - 0.22 11.4 1.7 84 3.0 0.0 3.9 4 0 0 4 4 4 0 NACHT domain AAA_25 PF13481.6 KPA41701.1 - 1.3 8.5 3.1 61 3.1 0.1 3.8 4 0 0 4 4 4 0 AAA domain DNA_methylase PF00145.17 KPA41702.1 - 1.2e-32 113.6 0.0 2.2e-31 109.5 0.0 2.2 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KPA41702.1 - 0.0084 16.0 0.0 0.047 13.6 0.0 2.1 2 0 0 2 2 2 1 BAH domain Drc1-Sld2 PF11719.8 KPA41703.1 - 2e-88 297.9 26.7 1.7e-87 294.8 26.7 1.9 1 1 0 1 1 1 1 DNA replication and checkpoint protein zf-RING_2 PF13639.6 KPA41704.1 - 1.2e-06 28.7 14.0 2e-06 28.0 14.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KPA41704.1 - 2.7e-05 23.9 10.3 4.7e-05 23.2 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPA41704.1 - 4.1e-05 23.4 10.6 6.1e-05 22.8 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KPA41704.1 - 0.0001 22.5 9.0 0.00023 21.4 9.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KPA41704.1 - 0.00015 21.5 13.2 0.00025 20.8 13.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF5343 PF17278.2 KPA41704.1 - 0.0037 17.4 0.0 0.0061 16.7 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5343) SapB_1 PF05184.15 KPA41704.1 - 0.022 14.8 0.8 0.088 12.9 0.0 2.5 3 0 0 3 3 3 0 Saposin-like type B, region 1 GAGA PF09237.11 KPA41704.1 - 0.041 13.7 0.1 0.13 12.1 0.1 1.9 1 0 0 1 1 1 0 GAGA factor DSBA PF01323.20 KPA41705.1 - 5.7e-29 101.3 0.0 6.6e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KPA41705.1 - 0.00079 19.4 0.3 0.021 14.9 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_4 PF13462.6 KPA41705.1 - 0.022 14.9 0.0 0.064 13.4 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_5 PF13743.6 KPA41705.1 - 0.12 12.0 0.0 0.99 9.1 0.0 2.2 3 0 0 3 3 3 0 Thioredoxin DASH_Spc34 PF08657.10 KPA41706.1 - 3.4e-38 131.9 21.3 1.9e-25 90.1 3.0 3.8 3 2 1 4 4 4 2 DASH complex subunit Spc34 Ribosomal_S10 PF00338.22 KPA41706.1 - 0.0052 17.0 0.0 0.054 13.7 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e PSCyt3 PF07627.11 KPA41706.1 - 0.012 15.9 0.4 8 6.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) CENP-Q PF13094.6 KPA41707.1 - 2.6e-47 161.2 8.2 2.6e-47 161.2 8.2 4.4 2 1 2 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit HALZ PF02183.18 KPA41707.1 - 0.068 13.4 2.1 3.7 7.9 0.3 2.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper BLOC1S3 PF15753.5 KPA41708.1 - 7.1 6.7 8.0 0.2 11.8 0.6 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 RTP1_C1 PF10363.9 KPA41709.1 - 6.1e-24 84.4 2.3 5.5e-23 81.3 0.1 3.3 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KPA41709.1 - 9.5e-13 47.6 0.3 6.1e-12 45.0 0.2 2.4 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 V-ATPase_H_N PF03224.14 KPA41709.1 - 0.00091 18.6 3.3 0.098 11.9 0.0 2.5 2 0 0 2 2 2 2 V-ATPase subunit H DUF5089 PF17002.5 KPA41709.1 - 0.013 15.4 4.6 0.34 10.7 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) Adaptin_N PF01602.20 KPA41709.1 - 0.042 12.4 1.2 0.057 12.0 0.1 1.7 2 0 0 2 2 2 0 Adaptin N terminal region Kinesin_assoc PF16183.5 KPA41709.1 - 0.055 13.6 0.1 0.19 11.9 0.1 2.0 1 0 0 1 1 1 0 Kinesin-associated DUF4704 PF15787.5 KPA41709.1 - 0.15 11.3 3.0 0.92 8.7 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) FAM176 PF14851.6 KPA41709.1 - 0.21 11.3 1.0 0.53 9.9 1.0 1.6 1 0 0 1 1 1 0 FAM176 family AATF-Che1 PF13339.6 KPA41709.1 - 0.46 11.2 5.0 0.12 13.1 0.7 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor RRN3 PF05327.11 KPA41709.1 - 3.7 6.0 6.5 3.1 6.2 2.3 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2183 PF09949.9 KPA41710.1 - 1.4e-20 73.4 0.1 2.6e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Flu_B_NS1 PF02942.14 KPA41711.1 - 0.25 10.4 0.1 0.28 10.2 0.1 1.1 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) OB_NTP_bind PF07717.16 KPA41712.1 - 1.3e-23 83.1 0.0 6.8e-23 80.8 0.0 2.2 3 0 0 3 3 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KPA41712.1 - 4.1e-19 68.8 0.0 1.6e-18 67.0 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KPA41712.1 - 7.3e-12 45.6 0.0 4.9e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPA41712.1 - 4.1e-08 33.2 0.2 8.5e-08 32.2 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KPA41712.1 - 4.7e-05 23.7 0.0 0.00014 22.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KPA41712.1 - 0.00018 21.2 0.1 0.0007 19.3 0.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 KPA41712.1 - 0.0049 16.0 0.0 0.0091 15.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KPA41712.1 - 0.0079 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPA41712.1 - 0.014 15.8 0.1 0.029 14.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KPA41712.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KPA41712.1 - 0.033 14.6 0.7 0.41 11.1 0.1 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PRMT5_TIM PF17285.2 KPA41713.1 - 2.1e-70 236.8 0.0 2.8e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KPA41713.1 - 4.4e-65 218.8 0.0 8.1e-65 217.9 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KPA41713.1 - 1.6e-59 200.8 0.0 2.4e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 KPA41713.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein S36_mt PF10937.8 KPA41714.1 - 3.1e-36 125.5 0.8 5.8e-36 124.6 0.8 1.4 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial DUF2183 PF09949.9 KPA41716.1 - 8.4e-33 112.7 0.0 2e-32 111.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF1992 PF09350.10 KPA41719.1 - 9.3e-22 77.0 0.9 3.2e-21 75.3 0.9 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) TT_ORF2 PF02957.15 KPA41719.1 - 0.0055 17.6 1.0 0.0055 17.6 1.0 2.2 3 0 0 3 3 3 1 TT viral ORF2 Ribosomal_L5_C PF00673.21 KPA41720.1 - 5.2e-29 100.3 0.0 1.1e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KPA41720.1 - 1.1e-08 35.3 0.0 2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Fes1 PF08609.10 KPA41721.1 - 3.4e-28 98.4 3.9 3.4e-28 98.4 3.9 2.2 2 1 1 3 3 3 1 Nucleotide exchange factor Fes1 Arm PF00514.23 KPA41721.1 - 3.4e-06 26.9 0.0 0.039 14.0 0.0 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KPA41721.1 - 8.4e-06 26.1 0.1 2e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 KPA41721.1 - 7.7e-05 23.1 1.1 0.0029 18.1 0.1 3.0 1 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KPA41721.1 - 0.0025 17.9 0.0 0.29 11.5 0.0 2.8 3 0 0 3 3 3 1 HEAT repeat Actin PF00022.19 KPA41722.1 - 1.3e-150 501.5 0.0 5.2e-150 499.6 0.0 1.7 1 1 0 1 1 1 1 Actin RF-1 PF00472.20 KPA41723.1 - 2.7e-24 85.3 4.6 4e-24 84.8 4.6 1.2 1 0 0 1 1 1 1 RF-1 domain SPT_ssu-like PF11779.8 KPA41724.1 - 5.8e-24 83.5 6.3 7.4e-24 83.1 6.3 1.1 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like L-fibroin PF05849.11 KPA41724.1 - 0.092 12.0 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) WD40 PF00400.32 KPA41725.1 - 1.2e-30 105.0 18.8 0.00016 22.4 0.0 10.5 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA41725.1 - 7.7e-05 22.9 0.4 5.6 7.3 0.0 6.4 5 3 2 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Urm1 PF09138.11 KPA41726.1 - 3.9e-35 120.1 0.0 4.4e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KPA41726.1 - 0.024 15.3 0.0 0.026 15.1 0.0 1.2 1 0 0 1 1 1 0 ThiS family zf-H2C2_2 PF13465.6 KPA41727.1 - 5.1e-18 64.6 16.5 7.2e-07 29.4 0.9 4.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KPA41727.1 - 3.2e-16 58.8 25.3 0.00013 22.2 0.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA41727.1 - 3.5e-08 33.6 21.0 0.013 16.3 0.4 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KPA41727.1 - 0.0013 18.9 8.5 0.055 13.8 1.3 3.5 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-met PF12874.7 KPA41727.1 - 0.014 15.8 12.6 0.42 11.1 0.3 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KPA41727.1 - 0.051 14.2 9.7 5.4 7.7 0.5 4.2 1 1 3 4 4 4 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KPA41727.1 - 0.19 11.8 14.9 1 9.4 0.5 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger C1_4 PF07975.12 KPA41727.1 - 0.89 9.8 5.8 4.6 7.6 0.4 2.8 3 0 0 3 3 3 0 TFIIH C1-like domain zf-C2H2_aberr PF17017.5 KPA41727.1 - 1.3 9.2 5.3 5.5 7.1 0.3 2.9 2 1 1 3 3 3 0 Aberrant zinc-finger zf-LYAR PF08790.11 KPA41727.1 - 2.6 8.0 9.2 1.5 8.8 0.3 3.7 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Mito_carr PF00153.27 KPA41728.1 - 1.4e-57 191.6 2.0 1.6e-19 69.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 KPA41729.1 - 1.6e-33 114.3 0.0 7.8e-16 57.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPA41729.1 - 0.0057 16.7 0.0 0.023 14.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 KPA41729.1 - 0.0067 16.0 0.0 0.058 13.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KPA41729.1 - 0.06 13.0 0.8 6.4 6.5 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KPA41729.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Cohesin_load PF10345.9 KPA41730.1 - 3.8e-28 98.3 0.4 4.6e-28 98.0 0.4 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_2 PF07719.17 KPA41730.1 - 0.02 14.9 0.3 0.058 13.5 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat XkdW PF09636.10 KPA41730.1 - 0.08 13.0 0.1 0.17 12.0 0.1 1.6 1 1 0 1 1 1 0 XkdW protein Transglut_core PF01841.19 KPA41731.1 - 7.4e-11 42.5 0.2 1.6e-10 41.4 0.2 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KPA41731.1 - 8.6e-08 31.7 0.1 2e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPA41731.1 - 0.00035 20.1 0.1 0.00035 20.1 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KPA41731.1 - 0.025 14.4 0.2 0.054 13.4 0.2 1.6 1 0 0 1 1 1 0 Variant SH3 domain Pkinase PF00069.25 KPA41732.1 - 2.6e-68 230.2 0.0 4.1e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA41732.1 - 6.7e-49 166.5 0.0 1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPA41732.1 - 2.8e-06 26.4 0.0 5.8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KPA41732.1 - 1e-05 25.0 0.0 2.7e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KPA41732.1 - 0.12 11.7 0.1 0.34 10.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KPA41732.1 - 0.13 11.2 0.0 0.41 9.5 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain RAI1 PF08652.11 KPA41733.1 - 2e-28 98.4 0.0 4.3e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Chromo PF00385.24 KPA41734.1 - 0.00025 20.9 1.1 0.00053 19.8 1.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain COX5A PF02284.16 KPA41735.1 - 4e-41 139.2 0.1 5.3e-41 138.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.18 KPA41736.1 - 1.2e-62 211.7 18.5 1.4e-62 211.4 18.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3290 PF11694.8 KPA41736.1 - 6.1 6.8 7.2 0.33 10.9 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) HET PF06985.11 KPA41737.1 - 1.7e-30 106.3 0.1 2.6e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4003 PF13170.6 KPA41737.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) F-box-like PF12937.7 KPA41738.1 - 1.8e-06 27.7 0.6 3.7e-06 26.7 0.6 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KPA41738.1 - 0.0009 19.6 0.6 5.5 7.6 0.9 3.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box PF00646.33 KPA41738.1 - 3.1 7.8 7.1 13 5.8 0.1 2.7 3 0 0 3 3 3 0 F-box domain HSP70 PF00012.20 KPA41741.1 - 0.0022 16.3 0.0 0.044 12.0 0.0 2.3 2 1 0 2 2 2 1 Hsp70 protein LysM PF01476.20 KPA41742.1 - 5.7e-11 42.3 0.4 0.0073 16.3 0.0 4.4 4 0 0 4 4 4 3 LysM domain LCE6A PF15858.5 KPA41742.1 - 7.9 7.3 8.5 50 4.7 0.2 3.6 3 0 0 3 3 3 0 Late cornified envelope protein 6A family Glyco_hydro_18 PF00704.28 KPA41743.1 - 1.5e-59 202.3 0.2 2.3e-59 201.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KPA41743.1 - 4.3e-11 43.1 15.5 4.3e-11 43.1 15.5 5.2 5 0 0 5 5 5 2 Chitin recognition protein BTB PF00651.31 KPA41745.1 - 3.2e-07 30.6 0.0 0.054 13.7 0.0 4.1 4 0 0 4 4 4 3 BTB/POZ domain SLC35F PF06027.12 KPA41746.1 - 7.5e-98 327.7 26.6 9.8e-98 327.3 26.6 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KPA41746.1 - 2.2e-11 43.3 3.2 2.2e-11 43.3 3.2 1.6 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KPA41746.1 - 7.7e-09 35.8 35.6 0.00027 21.1 13.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family Metallophos PF00149.28 KPA41747.1 - 2.3e-10 41.3 2.3 5.1e-10 40.2 2.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KPA41747.1 - 0.00014 22.1 0.0 0.0005 20.3 0.0 1.8 1 1 1 2 2 2 1 5'-nucleotidase, C-terminal domain B12-binding PF02310.19 KPA41747.1 - 0.099 12.7 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain EMC1_C PF07774.13 KPA41749.1 - 1.4e-69 234.0 0.0 2.6e-69 233.1 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KPA41749.1 - 1.4e-24 87.0 7.7 2.1e-19 70.1 3.5 2.5 2 0 0 2 2 2 2 PQQ-like domain DUF4381 PF14316.6 KPA41750.1 - 1.9 8.7 4.8 2.7 8.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Nop14 PF04147.12 KPA41751.1 - 4.1 5.5 11.7 0.48 8.6 7.1 1.7 2 0 0 2 2 2 0 Nop14-like family Complex1_LYR PF05347.15 KPA41752.1 - 8.3e-21 73.8 3.4 1.3e-20 73.1 3.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KPA41752.1 - 4.7e-06 27.3 2.5 5.7e-06 27.0 2.5 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KPA41752.1 - 0.0012 19.4 0.3 0.0015 19.1 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like VitD-bind_III PF09164.10 KPA41752.1 - 0.029 14.3 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Vitamin D binding protein, domain III WD40 PF00400.32 KPA41753.1 - 4.8e-09 36.7 6.8 0.0091 16.8 0.2 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_3 PF13570.6 KPA41753.1 - 0.14 12.7 0.2 12 6.5 0.0 3.2 3 1 0 3 3 3 0 PQQ-like domain DUF4691 PF15762.5 KPA41754.1 - 0.031 14.4 0.5 0.071 13.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4691) CLN3 PF02487.17 KPA41756.1 - 1.2e-41 143.2 10.6 5.4e-41 141.0 10.6 1.8 1 1 0 1 1 1 1 CLN3 protein Zn_clus PF00172.18 KPA41757.1 - 1.9e-08 34.3 5.5 3.6e-08 33.4 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAPRTase PF04095.16 KPA41758.1 - 4.9e-58 196.6 0.8 2.4e-54 184.5 0.8 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KPA41758.1 - 1.9e-35 121.9 0.0 3.7e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain WD40 PF00400.32 KPA41759.1 - 3.4e-09 37.2 12.8 0.69 10.9 0.0 8.6 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA41759.1 - 9.4e-07 29.0 0.2 0.17 12.2 0.0 5.4 4 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KPA41759.1 - 0.00012 21.8 1.9 0.0028 17.3 1.7 3.2 1 1 1 2 2 2 2 PQQ-like domain Rad4 PF03835.15 KPA41760.1 - 1.4e-15 57.2 3.5 2.7e-15 56.4 3.5 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KPA41760.1 - 7.5e-12 45.7 2.9 1.9e-11 44.4 2.9 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily zf-RING_2 PF13639.6 KPA41761.1 - 1.7e-09 37.9 9.8 1.7e-09 37.9 9.8 2.5 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 KPA41761.1 - 1.5e-08 34.6 3.0 1.5e-08 34.6 3.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KPA41761.1 - 1.6e-07 31.5 8.8 1.6e-07 31.5 8.8 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KPA41761.1 - 8.9e-06 25.6 7.1 8.9e-06 25.6 7.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KPA41761.1 - 3.6e-05 23.6 10.0 3.6e-05 23.6 10.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KPA41761.1 - 0.00027 20.7 9.2 0.00067 19.4 9.2 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 KPA41761.1 - 0.0026 17.7 9.0 0.0026 17.7 9.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain FANCL_C PF11793.8 KPA41761.1 - 0.003 17.7 9.7 0.003 17.7 9.7 2.6 2 1 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 KPA41761.1 - 0.0044 16.8 10.7 0.0044 16.8 10.7 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPA41761.1 - 0.0065 16.2 7.0 0.0065 16.2 7.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 KPA41761.1 - 0.0083 16.0 2.6 0.0083 16.0 2.6 3.3 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 PHD PF00628.29 KPA41761.1 - 0.02 14.7 10.9 0.056 13.4 10.9 1.8 1 0 0 1 1 1 0 PHD-finger zf-UDP PF14569.6 KPA41761.1 - 0.025 14.7 3.4 0.025 14.7 3.4 2.0 2 0 0 2 2 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 KPA41761.1 - 0.031 14.4 4.2 0.031 14.4 4.2 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KPA41761.1 - 0.034 14.5 4.9 0.034 14.5 4.9 3.1 3 1 1 4 4 2 0 RING-like domain RINGv PF12906.7 KPA41761.1 - 0.18 12.0 11.0 0.56 10.4 11.0 1.9 1 0 0 1 1 1 0 RING-variant domain Ndc1_Nup PF09531.10 KPA41761.1 - 0.22 10.2 2.4 0.24 10.1 2.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Synthase_beta PF11421.8 KPA41761.1 - 2.9 8.7 6.6 1.3 9.8 2.0 2.4 1 1 1 2 2 2 0 ATP synthase F1 beta subunit RR_TM4-6 PF06459.12 KPA41761.1 - 3.6 7.3 7.6 6.4 6.5 7.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-C3HC4_3 PF13920.6 KPA41761.1 - 4.1 7.4 16.2 0.038 13.9 7.4 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Presenilin PF01080.17 KPA41761.1 - 9.3 4.9 6.0 13 4.4 6.0 1.2 1 0 0 1 1 1 0 Presenilin ADH_N PF08240.12 KPA41762.1 - 6.3e-09 35.7 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPA41762.1 - 1.3e-06 29.5 0.0 2.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase C6_DPF PF10170.9 KPA41766.1 - 0.027 14.9 3.8 0.054 13.9 3.8 1.6 1 0 0 1 1 1 0 Cysteine-rich domain FAM196 PF15265.6 KPA41766.1 - 0.98 8.8 10.5 1.2 8.6 10.5 1.1 1 0 0 1 1 1 0 FAM196 family FYVE_2 PF02318.16 KPA41766.1 - 3.3 8.0 7.7 6.3 7.0 7.4 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger PQ-loop PF04193.14 KPA41767.1 - 4e-25 87.4 2.4 9e-14 51.0 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF3408 PF11888.8 KPA41768.1 - 3.9 7.6 9.5 12 6.1 9.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) BATS PF06968.13 KPA41769.1 - 4.8e-24 84.3 0.7 1.1e-23 83.1 0.1 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KPA41769.1 - 1.1e-16 61.6 0.1 5.5e-16 59.4 0.1 2.0 2 0 0 2 2 2 1 Radical SAM superfamily SinI PF08671.10 KPA41770.1 - 0.22 11.4 2.1 0.49 10.2 2.1 1.6 1 0 0 1 1 1 0 Anti-repressor SinI DUF1656 PF07869.12 KPA41770.1 - 0.96 9.5 6.7 0.15 12.1 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Bromodomain PF00439.25 KPA41771.1 - 7.7e-24 83.6 0.5 1.9e-23 82.4 0.5 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KPA41771.1 - 6.2e-08 32.9 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA41771.1 - 4.8e-07 29.8 0.2 1.1e-06 28.6 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA41771.1 - 0.00031 21.1 0.4 0.00062 20.1 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ost5 PF05251.12 KPA41772.1 - 4.6e-21 74.9 9.0 7.2e-21 74.2 9.0 1.3 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Rad1 PF02144.16 KPA41773.1 - 1.1e-73 247.6 0.0 1.3e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad4 PF03835.15 KPA41774.1 - 9.3e-15 54.6 1.7 2e-14 53.5 1.7 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KPA41774.1 - 8.8e-13 48.7 2.1 2e-12 47.6 2.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Fructosamin_kin PF03881.14 KPA41776.1 - 1.7e-35 122.7 0.0 2.2e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KPA41776.1 - 1.3e-05 25.3 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family ANAPC4_WD40 PF12894.7 KPA41777.1 - 2e-10 40.8 0.0 0.024 14.9 0.0 6.3 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KPA41777.1 - 1.6e-05 24.9 0.1 0.0001 22.3 0.0 2.2 2 0 0 2 2 2 1 NACHT domain WD40 PF00400.32 KPA41777.1 - 6.2e-05 23.7 0.0 0.87 10.6 0.0 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat YqgC PF17430.2 KPA41777.1 - 0.19 11.8 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized YqgC-like Lsm_interact PF05391.11 KPA41778.1 - 0.031 13.8 0.0 0.096 12.2 0.0 1.8 1 0 0 1 1 1 0 Lsm interaction motif DUF3197 PF11432.8 KPA41779.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) Peptidase_C12 PF01088.21 KPA41780.1 - 1.9e-50 171.5 0.0 2.2e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 OPT PF03169.15 KPA41781.1 - 3.7e-183 610.5 51.4 4.2e-183 610.3 51.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein EIAV_GP90 PF00971.18 KPA41781.1 - 4.1 6.0 6.2 0.41 9.3 0.1 2.0 2 0 0 2 2 2 0 EIAV coat protein, gp90 Ribosomal_L37e PF01907.19 KPA41782.1 - 4.4e-28 97.2 11.2 6.5e-28 96.7 11.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e zf-C4pol PF14260.6 KPA41782.1 - 0.016 15.6 0.7 0.025 15.1 0.7 1.4 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 KPA41782.1 - 0.02 14.9 1.0 0.031 14.3 1.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KPA41782.1 - 0.07 13.2 0.8 0.095 12.7 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin_2 PF18073.1 KPA41782.1 - 0.072 12.8 1.9 1.7 8.4 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_2 PF13240.6 KPA41782.1 - 0.43 10.4 3.6 11 5.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_S14 PF00253.21 KPA41782.1 - 0.48 10.2 8.0 0.99 9.2 0.1 2.6 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e DUF1258 PF06869.12 KPA41782.1 - 0.65 9.4 3.4 0.43 10.0 1.9 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) zf-C3HC4_2 PF13923.6 KPA41782.1 - 0.86 9.5 5.5 1.4 8.8 5.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ELP6 PF09807.9 KPA41783.1 - 8.2e-11 41.8 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Elongation complex protein 6 ATPase PF06745.13 KPA41783.1 - 2.7e-07 30.2 0.0 3.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 KaiC Elong_Iki1 PF10483.9 KPA41783.1 - 0.045 13.2 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 Thioredoxin PF00085.20 KPA41784.1 - 3.8e-08 33.3 0.0 6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KPA41784.1 - 0.016 15.5 0.0 0.1 12.9 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 KPA41784.1 - 0.049 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KPA41784.1 - 0.081 12.6 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Redoxin DUF953 PF06110.11 KPA41784.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.6 KPA41784.1 - 0.13 12.7 0.0 1.1 9.7 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.21 KPA41784.1 - 0.15 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family MFS_1 PF07690.16 KPA41785.1 - 5.3e-38 130.9 21.6 5.3e-38 130.9 21.6 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA41785.1 - 2.4e-11 43.2 6.7 2.4e-11 43.2 6.7 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KPA41785.1 - 0.00097 17.7 1.5 0.0016 17.0 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Neur_chan_memb PF02932.16 KPA41785.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3306 PF11748.8 KPA41785.1 - 0.022 15.6 2.5 0.022 15.6 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) PRT_C PF08372.10 KPA41785.1 - 0.13 12.1 0.9 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal MFA1_2 PF17317.2 KPA41785.1 - 0.21 11.4 0.0 0.57 10.0 0.0 1.7 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 MSA-2c PF12238.8 KPA41785.1 - 0.44 10.5 4.9 1 9.3 4.9 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c Dishevelled PF02377.15 KPA41785.1 - 1 9.8 7.8 2 8.9 7.8 1.4 1 0 0 1 1 1 0 Dishevelled specific domain Sel1 PF08238.12 KPA41786.1 - 5.5e-43 144.4 22.9 1.3e-07 32.0 0.0 7.8 7 0 0 7 7 7 7 Sel1 repeat ANAPC3 PF12895.7 KPA41786.1 - 0.00092 19.4 2.7 0.0038 17.4 1.8 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KPA41786.1 - 0.099 12.3 7.5 7.4 6.3 0.1 4.3 4 0 0 4 4 4 0 TPR repeat FIST_C PF10442.9 KPA41786.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 FIST C domain TPR_17 PF13431.6 KPA41786.1 - 0.16 12.4 1.3 12 6.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CBP4 PF07960.11 KPA41787.1 - 1.6e-29 102.3 2.9 2e-29 102.1 2.9 1.0 1 0 0 1 1 1 1 CBP4 DUF2852 PF11014.8 KPA41787.1 - 0.88 9.7 6.9 0.15 12.2 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) NAC PF01849.18 KPA41788.1 - 4.2e-23 81.1 0.3 2.4e-22 78.6 0.1 2.0 2 0 0 2 2 2 1 NAC domain A_deamin PF02137.18 KPA41789.1 - 1.4e-35 123.3 0.2 1.8e-35 123.0 0.2 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF1378 PF07125.11 KPA41789.1 - 0.31 11.2 1.5 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) Ribosomal_L24e PF01246.20 KPA41790.1 - 4.9e-28 97.1 0.1 4.9e-28 97.1 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Redoxin PF08534.10 KPA41791.1 - 2.6e-35 121.3 0.0 2.7e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KPA41791.1 - 1.5e-08 34.6 0.0 1.9e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Pea-VEAacid PF08111.11 KPA41791.1 - 0.015 15.6 0.1 0.043 14.1 0.1 1.8 1 0 0 1 1 1 0 Pea-VEAacid family HD_3 PF13023.6 KPA41792.1 - 4.1e-45 153.7 0.0 5e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KPA41792.1 - 2.6e-11 43.6 0.0 5e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KPA41792.1 - 0.00043 20.5 0.0 0.0015 18.8 0.0 1.8 1 1 0 1 1 1 1 HD domain RGS PF00615.19 KPA41793.1 - 3.7e-06 27.2 0.3 0.0073 16.6 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Fumble PF03630.14 KPA41794.1 - 1.8e-145 484.3 0.1 2.2e-145 484.0 0.1 1.1 1 0 0 1 1 1 1 Fumble DUF5399 PF17377.2 KPA41795.1 - 0.13 12.0 3.5 0.27 11.0 3.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5399) zf-PARP PF00645.18 KPA41797.1 - 2.3e-21 76.4 3.8 8.1e-21 74.7 3.8 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF2576 PF10845.8 KPA41797.1 - 0.13 11.9 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) PI3_PI4_kinase PF00454.27 KPA41798.1 - 1.4e-49 169.2 0.0 2.4e-49 168.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KPA41798.1 - 4e-35 121.7 3.0 7e-35 120.8 3.0 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KPA41798.1 - 1.1e-28 99.1 0.0 7.1e-28 96.5 0.0 2.6 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 KPA41798.1 - 1.1e-16 60.4 0.0 4.9e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 FATC domain HSP70 PF00012.20 KPA41798.1 - 2.9e-11 42.3 0.0 1.2e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein DHR10 PF18595.1 KPA41799.1 - 0.013 15.5 13.0 0.013 15.5 13.0 2.0 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FAM76 PF16046.5 KPA41799.1 - 0.048 13.0 5.2 0.16 11.3 5.1 1.7 2 0 0 2 2 2 0 FAM76 protein YabA PF06156.13 KPA41799.1 - 0.22 12.2 1.0 0.5 11.0 0.4 1.9 2 0 0 2 2 2 0 Initiation control protein YabA DUF745 PF05335.13 KPA41799.1 - 0.24 11.1 3.3 0.48 10.1 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) FlaC_arch PF05377.11 KPA41799.1 - 0.24 11.8 2.1 24 5.4 0.9 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1451 PF07295.11 KPA41799.1 - 0.39 10.8 5.6 1.1 9.3 3.6 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain BBP1_C PF15272.6 KPA41799.1 - 0.76 9.6 7.0 1.4 8.7 7.0 1.4 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal UPF0242 PF06785.11 KPA41799.1 - 1.5 8.9 7.3 2.5 8.2 7.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 KPA41799.1 - 2.4 6.9 3.4 3.6 6.4 3.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Jnk-SapK_ap_N PF09744.9 KPA41799.1 - 2.6 8.3 16.7 0.66 10.2 13.5 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 KPA41799.1 - 2.8 8.6 8.6 51 4.6 5.2 2.9 2 1 0 2 2 2 0 SlyX DUF5082 PF16888.5 KPA41799.1 - 4 7.7 8.4 5.4 7.3 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) GGACT PF06094.12 KPA41800.1 - 9.2e-10 39.2 0.1 1.5e-09 38.5 0.1 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KPA41800.1 - 2e-05 24.9 0.0 0.00011 22.5 0.0 2.1 1 1 0 1 1 1 1 AIG2-like family Nucleo_P87 PF07267.11 KPA41800.1 - 3.4 6.4 4.6 4.3 6.1 4.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Amidoligase_2 PF12224.8 KPA41801.1 - 1.2e-12 48.0 0.0 1.9e-12 47.4 0.0 1.3 1 1 0 1 1 1 1 Putative amidoligase enzyme CPSase_L_D2 PF02786.17 KPA41802.1 - 4.6e-72 241.9 0.0 7.5e-72 241.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KPA41802.1 - 1.1e-35 122.0 0.0 2.1e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KPA41802.1 - 1.7e-35 121.9 0.0 4.7e-35 120.5 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KPA41802.1 - 2.8e-16 59.1 2.6 5.9e-16 58.1 1.7 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KPA41802.1 - 5.5e-09 35.7 0.1 0.002 17.9 0.0 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.22 KPA41802.1 - 4.6e-07 29.6 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KPA41802.1 - 3.5e-06 26.7 0.0 1.1e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 KPA41802.1 - 2.8e-05 24.8 0.0 0.67 10.7 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 KPA41802.1 - 0.0022 17.3 0.0 1.8 7.7 0.0 2.8 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 KPA41802.1 - 0.0043 17.1 0.0 0.0094 16.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Putative_PNPOx PF01243.20 KPA41803.1 - 1.2e-11 44.6 0.0 2.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KPA41803.1 - 0.0098 15.9 0.0 0.073 13.1 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Mem_trans PF03547.18 KPA41804.1 - 4.8e-53 180.0 3.5 2.6e-52 177.5 3.5 1.8 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.25 KPA41805.1 - 2.9e-54 184.2 0.0 5.6e-51 173.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA41805.1 - 2.4e-32 112.2 0.0 6.4e-31 107.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA41805.1 - 0.00013 21.4 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KPA41805.1 - 0.0013 17.9 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 KPA41805.1 - 0.0027 16.7 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KPA41805.1 - 0.082 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KPA41805.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SUR7 PF06687.12 KPA41806.1 - 3.5e-30 105.2 10.9 4.2e-30 105.0 10.9 1.0 1 0 0 1 1 1 1 SUR7/PalI family Glucan_synthase PF02364.15 KPA41806.1 - 1.9 6.5 3.7 3.1 5.9 3.7 1.3 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Clc-like PF07062.12 KPA41806.1 - 2.6 7.5 7.3 0.25 10.8 2.8 1.5 2 0 0 2 2 2 0 Clc-like YpmT PF17431.2 KPA41806.1 - 8.1 6.6 8.2 7.9 6.6 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized YmpT-like BPL_LplA_LipB PF03099.19 KPA41807.1 - 4e-05 23.5 0.0 7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ALO PF04030.14 KPA41808.1 - 1.1e-93 313.8 0.2 1.5e-93 313.4 0.2 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KPA41808.1 - 1.4e-29 102.6 0.0 2e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF2510 PF10708.9 KPA41808.1 - 0.14 12.0 2.2 3.9 7.3 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2510) Tetraspanin PF00335.20 KPA41809.1 - 4.8e-05 23.2 12.1 6.7e-05 22.7 12.1 1.2 1 0 0 1 1 1 1 Tetraspanin family Sensor PF13796.6 KPA41809.1 - 0.014 15.5 3.5 0.17 11.9 3.5 2.2 2 0 0 2 2 2 0 Putative sensor DUF2054 PF10218.9 KPA41809.1 - 0.051 13.7 1.3 0.84 9.7 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2054) Branch PF02485.21 KPA41809.1 - 0.083 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Core-2/I-Branching enzyme SRF-TF PF00319.18 KPA41810.1 - 4.5e-21 74.1 0.1 6.3e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.14 KPA41810.1 - 0.16 10.3 0.6 0.2 9.9 0.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Ctr PF04145.15 KPA41811.1 - 1.5e-31 110.0 0.1 1.8e-31 109.7 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF3012 PF11216.8 KPA41811.1 - 0.11 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) DUF2585 PF10755.9 KPA41811.1 - 0.13 12.0 0.7 0.18 11.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2585) DUF2975 PF11188.8 KPA41811.1 - 0.18 11.7 5.1 0.6 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) ABC_tran PF00005.27 KPA41812.1 - 1.6e-32 112.9 0.0 4.2e-32 111.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KPA41812.1 - 5.9e-26 91.7 4.9 1.3e-25 90.6 4.9 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KPA41812.1 - 9.5e-05 21.9 0.0 0.00039 19.9 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KPA41812.1 - 0.0059 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_24 PF13479.6 KPA41812.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KPA41812.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 KPA41812.1 - 0.053 13.8 0.3 1 9.6 0.3 2.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit TRAM_LAG1_CLN8 PF03798.16 KPA41813.1 - 1.6e-34 119.4 16.6 3.3e-34 118.4 16.6 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KPA41813.1 - 1.1e-25 89.0 0.2 2.6e-25 87.9 0.2 1.7 1 0 0 1 1 1 1 TRAM1-like protein PalH PF08733.10 KPA41814.1 - 2.4e-114 381.8 0.4 3.2e-114 381.4 0.4 1.2 1 0 0 1 1 1 1 PalH/RIM21 DUF4521 PF15021.6 KPA41814.1 - 0.45 10.4 4.8 0.9 9.4 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) YjeF_N PF03853.15 KPA41815.1 - 6.9e-37 126.9 0.1 1.1e-36 126.3 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KPA41815.1 - 2.4e-08 34.8 1.1 2.4e-08 34.8 1.1 2.1 2 0 0 2 2 2 1 FDF domain PIF1 PF05970.14 KPA41817.1 - 9e-61 206.0 0.9 9.5e-47 159.9 0.0 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KPA41817.1 - 1.8e-22 80.0 0.0 3.4e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPA41817.1 - 3.2e-11 43.8 0.0 7.8e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KPA41817.1 - 3.4e-07 30.6 0.1 1.5e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KPA41817.1 - 6.6e-06 25.8 0.9 2.5e-05 23.9 0.0 2.2 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_16 PF13191.6 KPA41817.1 - 0.00056 20.3 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KPA41817.1 - 0.0006 19.0 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C_2 PF13538.6 KPA41817.1 - 0.00066 19.5 0.4 0.0024 17.6 0.1 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 KPA41817.1 - 0.0008 17.5 0.2 0.0065 14.5 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA PF00004.29 KPA41817.1 - 0.0043 17.5 0.1 0.013 15.9 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KPA41817.1 - 0.0049 16.8 0.1 0.02 14.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain PhoH PF02562.16 KPA41817.1 - 0.005 16.3 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 KPA41817.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KPA41817.1 - 0.011 16.1 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 KPA41817.1 - 0.012 15.4 0.1 5.2 6.7 0.0 2.8 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KPA41817.1 - 0.018 15.1 0.3 0.018 15.1 0.3 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KPA41817.1 - 0.019 15.5 0.1 0.019 15.5 0.1 2.1 1 1 1 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 KPA41817.1 - 0.024 14.4 0.1 0.074 12.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 KPA41817.1 - 0.029 13.6 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF815 PF05673.13 KPA41817.1 - 0.041 13.0 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PAS PF00989.25 KPA41817.1 - 0.042 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 PAS fold AAA_11 PF13086.6 KPA41817.1 - 0.045 13.5 0.0 0.045 13.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KPA41817.1 - 0.051 13.6 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KPA41817.1 - 0.052 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KPA41817.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KPA41817.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 KPA41817.1 - 0.13 11.7 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KPA41817.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF5605 PF18310.1 KPA41817.1 - 0.18 11.7 0.0 0.51 10.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) DUF87 PF01935.17 KPA41817.1 - 0.75 9.8 6.7 0.96 9.5 0.3 2.7 1 1 1 2 2 2 0 Helicase HerA, central domain SH3_13 PF18335.1 KPA41817.1 - 1 9.2 3.3 1.2 9.0 0.1 2.8 3 0 0 3 3 2 0 ATP-dependent RecD-like DNA helicase SH3 domain SF-assemblin PF06705.11 KPA41818.1 - 0.037 13.4 1.7 0.061 12.6 1.7 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Phage_terminase PF10668.9 KPA41818.1 - 0.071 13.1 1.4 0.46 10.5 1.4 2.5 1 0 0 1 1 1 0 Phage terminase small subunit Cullin PF00888.22 KPA41819.1 - 2.5e-177 591.2 0.0 3.5e-177 590.8 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KPA41819.1 - 6.5e-25 86.9 0.5 2.2e-24 85.3 0.5 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain PI3_PI4_kinase PF00454.27 KPA41820.1 - 1.7e-50 172.2 0.0 5.5e-50 170.5 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KPA41820.1 - 2.7e-50 170.4 2.5 8.3e-50 168.8 0.0 2.7 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KPA41820.1 - 1.3e-11 44.0 1.1 4.2e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 FATC domain DUF1186 PF06685.11 KPA41820.1 - 0.032 13.6 0.0 0.079 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) Nup192 PF11894.8 KPA41821.1 - 0 1574.2 0.6 0 1574.0 0.6 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF1286 PF06939.11 KPA41821.1 - 0.15 12.4 0.0 2.6 8.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1286) zf-C3HC4_3 PF13920.6 KPA41822.1 - 1.1e-09 38.0 10.7 1.6e-09 37.5 10.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA41822.1 - 1.2e-06 28.2 13.9 2e-06 27.5 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KPA41822.1 - 3.2e-06 27.1 7.8 4e-06 26.8 6.4 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KPA41822.1 - 5e-06 26.3 10.5 8.4e-06 25.6 10.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KPA41822.1 - 1.9e-05 24.5 12.9 3.3e-05 23.7 12.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KPA41822.1 - 2.1e-05 24.8 12.0 2.1e-05 24.8 12.0 1.5 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 KPA41822.1 - 0.00013 21.7 13.2 0.00023 21.0 13.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA41822.1 - 0.00015 21.8 9.7 0.00035 20.5 9.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 KPA41822.1 - 0.022 14.5 8.7 0.039 13.7 8.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 KPA41822.1 - 0.035 13.9 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-rbx1 PF12678.7 KPA41822.1 - 0.086 13.1 9.2 0.11 12.8 7.7 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KPA41822.1 - 0.16 12.2 11.5 0.3 11.3 11.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DNApol_Exo PF18136.1 KPA41823.1 - 1.8e-102 342.3 0.0 3.3e-102 341.4 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KPA41823.1 - 3e-55 187.8 0.0 6.1e-55 186.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A HTH_DeoR PF08220.12 KPA41823.1 - 0.16 11.8 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Kinetochor_Ybp2 PF08568.10 KPA41824.1 - 7.6e-97 325.3 0.0 9.4e-97 325.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Glyco_transf_28 PF03033.20 KPA41825.1 - 7.1e-17 61.7 0.2 1.5e-15 57.5 0.2 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KPA41825.1 - 2.2e-05 23.5 0.0 3.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KPA41825.1 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 KPA41825.1 - 0.0018 18.6 0.0 0.028 14.8 0.0 2.7 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain OAM_dimer PF16554.5 KPA41825.1 - 0.15 12.5 0.1 2 8.9 0.0 2.7 2 1 1 3 3 3 0 Dimerisation domain of d-ornithine 4,5-aminomutase G-patch_2 PF12656.7 KPA41826.1 - 2.6e-19 69.0 0.6 2.6e-19 69.0 0.6 3.6 3 1 0 3 3 3 1 G-patch domain Myb_DNA-bind_6 PF13921.6 KPA41827.1 - 5.2e-16 58.6 0.2 1.3e-15 57.3 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 KPA41827.1 - 1.6e-14 53.9 0.1 1.6e-14 53.9 0.1 3.7 4 0 0 4 4 4 1 HSA Myb_DNA-binding PF00249.31 KPA41827.1 - 0.00023 21.3 1.1 0.00038 20.6 0.3 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Cdh1_DBD_1 PF18196.1 KPA41827.1 - 0.45 10.8 4.5 0.38 11.1 0.1 2.9 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 UPF0242 PF06785.11 KPA41827.1 - 0.76 9.8 6.4 1.8 8.6 6.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Na_H_Exchanger PF00999.21 KPA41828.1 - 2.2e-73 247.3 40.9 2.7e-73 247.0 40.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Arf PF00025.21 KPA41829.1 - 3.9e-40 137.2 0.0 6.3e-40 136.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KPA41829.1 - 1.9e-15 56.9 0.0 9e-11 41.5 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KPA41829.1 - 2e-09 37.7 0.0 3.8e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KPA41829.1 - 3.8e-09 36.3 0.0 1.5e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KPA41829.1 - 7.5e-09 35.3 0.0 8.7e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KPA41829.1 - 9.8e-09 34.9 0.0 2.1e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPA41829.1 - 0.00019 21.5 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPA41829.1 - 0.0014 18.2 0.2 0.0054 16.3 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RNase_PH PF01138.21 KPA41830.1 - 2.7e-25 89.4 0.0 3.9e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KPA41830.1 - 5.8e-07 29.4 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 KPA41831.1 - 5.9e-79 265.3 22.8 6.7e-79 265.1 22.8 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 KPA41831.1 - 0.29 9.4 20.3 0.32 9.2 20.3 1.1 1 0 0 1 1 1 0 CDC45-like protein GEMIN8 PF15348.6 KPA41831.1 - 0.31 11.3 9.3 0.36 11.1 9.3 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 SAPS PF04499.15 KPA41831.1 - 1.7 7.4 11.3 2 7.1 11.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 KPA41831.1 - 3.5 6.1 15.1 4.2 5.8 15.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 KPA41831.1 - 3.6 5.7 23.5 4.8 5.3 23.5 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 KPA41831.1 - 6.6 5.4 4.9 7.6 5.2 4.9 1.1 1 0 0 1 1 1 0 Presenilin FGGY_C PF02782.16 KPA41832.1 - 1.9e-23 83.2 0.0 5.3e-23 81.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KPA41832.1 - 4e-21 75.7 0.0 7.2e-12 45.4 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Nuc_deoxyri_tr2 PF15891.5 KPA41832.1 - 0.055 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like Cation_efflux PF01545.21 KPA41833.1 - 1.6e-48 165.1 6.3 2.4e-48 164.5 6.3 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KPA41833.1 - 1.6e-05 24.9 0.1 4.3e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter SIR2 PF02146.17 KPA41834.1 - 6.9e-33 114.0 0.0 1e-32 113.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF5321 PF17254.2 KPA41835.1 - 2.2e-55 186.5 2.2 2.7e-55 186.2 2.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DUF3708 PF12501.8 KPA41835.1 - 0.03 14.1 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF2206 PF09971.9 KPA41835.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Peptidase_C50 PF03568.17 KPA41836.1 - 8e-164 545.5 0.0 4.1e-163 543.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 KPA41836.1 - 7.3e-10 39.0 21.0 7.9e-06 26.1 0.7 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat CHAT PF12770.7 KPA41836.1 - 4.2e-05 23.1 2.1 0.011 15.1 0.0 3.5 2 1 1 3 3 3 1 CHAT domain DUF2959 PF11172.8 KPA41836.1 - 0.024 14.8 1.9 0.056 13.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) G-gamma PF00631.22 KPA41836.1 - 0.14 12.2 0.0 0.9 9.6 0.0 2.3 2 0 0 2 2 2 0 GGL domain TPR_2 PF07719.17 KPA41836.1 - 2.6 8.4 18.7 4.7 7.6 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPA41836.1 - 2.8 7.9 6.9 51 3.9 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Sec15 PF04091.12 KPA41837.1 - 3.5e-113 378.2 5.6 3.5e-113 378.2 5.6 2.2 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF3510 PF12022.8 KPA41837.1 - 0.0013 19.1 0.5 4.7 7.6 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3510) Mre11_DNA_bind PF04152.14 KPA41837.1 - 0.36 11.1 3.3 0.46 10.8 0.1 2.8 2 2 1 3 3 3 0 Mre11 DNA-binding presumed domain COG5 PF10392.9 KPA41837.1 - 0.54 10.4 10.0 0.31 11.2 3.3 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 BORCS8 PF10167.9 KPA41837.1 - 0.59 10.1 3.7 24 4.9 1.1 3.0 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 TPR_MLP1_2 PF07926.12 KPA41837.1 - 0.7 10.0 7.2 0.68 10.0 1.5 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein BET PF17035.5 KPA41837.1 - 0.85 9.8 7.7 11 6.3 0.1 4.4 4 1 0 4 4 4 0 Bromodomain extra-terminal - transcription regulation Baculo_PEP_C PF04513.12 KPA41837.1 - 1.9 8.5 15.1 0.34 10.9 5.6 3.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CBFD_NFYB_HMF PF00808.23 KPA41838.1 - 2.4e-19 69.4 0.5 3.9e-19 68.7 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KPA41838.1 - 2.1e-15 57.3 0.2 2.1e-15 57.3 0.2 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KPA41838.1 - 0.042 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X DUF5583 PF17821.1 KPA41838.1 - 0.2 11.6 1.0 0.5 10.3 0.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5583) Fcf2 PF08698.11 KPA41839.1 - 1.9e-32 111.5 0.6 4.7e-32 110.2 0.1 1.9 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing Ribosomal_S10 PF00338.22 KPA41840.1 - 2.4e-24 85.4 0.0 5.9e-24 84.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e tRNA-synt_1b PF00579.25 KPA41841.1 - 1.8e-73 247.4 0.0 2.3e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Xpo1 PF08389.12 KPA41842.1 - 9.3e-07 29.0 0.2 7.6e-05 22.8 0.4 3.5 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 KPA41842.1 - 0.022 15.0 0.3 0.34 11.3 0.1 3.3 2 0 0 2 2 2 0 HEAT repeat Importin_rep_3 PF18806.1 KPA41842.1 - 0.031 14.3 0.0 0.57 10.3 0.0 2.9 2 0 0 2 2 2 0 Importin 13 repeat Importin_rep PF18773.1 KPA41842.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Importin 13 repeat DB_JBP1 PF18526.1 KPA41842.1 - 0.18 11.8 0.4 1.4 8.8 0.2 2.2 2 0 0 2 2 2 0 Thymine dioxygenase JBP1 DNA-binding domain Creatinase_N_2 PF16189.5 KPA41843.1 - 7.6e-50 169.2 0.2 1.2e-48 165.2 0.0 2.4 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KPA41843.1 - 1e-45 156.0 0.0 1.5e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KPA41843.1 - 2.6e-22 78.6 0.2 1.2e-21 76.6 0.1 2.1 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KPA41843.1 - 1.9e-21 77.1 0.0 7.7e-19 68.7 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Histone PF00125.24 KPA41844.1 - 1e-40 139.1 0.3 1.4e-40 138.7 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KPA41844.1 - 0.00045 20.3 0.1 0.00072 19.6 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KPA41844.1 - 0.00099 19.4 0.2 0.0019 18.6 0.2 1.4 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KPA41844.1 - 0.034 14.4 0.2 0.057 13.7 0.2 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FA_synthesis PF02504.15 KPA41844.1 - 0.19 10.8 0.1 0.24 10.4 0.1 1.1 1 0 0 1 1 1 0 Fatty acid synthesis protein FUN14 PF04930.15 KPA41844.1 - 1.3 9.5 5.8 6.2 7.3 5.8 2.0 1 1 0 1 1 1 0 FUN14 family DER1 PF04511.15 KPA41845.1 - 1.1e-51 175.6 5.6 1.2e-51 175.4 5.6 1.0 1 0 0 1 1 1 1 Der1-like family ARD PF03079.14 KPA41846.1 - 6.2e-47 159.7 0.0 7.6e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KPA41846.1 - 3.8e-08 32.9 0.0 6.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KPA41846.1 - 6.7e-07 29.3 0.0 9.7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain adh_short PF00106.25 KPA41847.1 - 4.3e-30 104.6 0.0 5.9e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA41847.1 - 4.7e-21 75.4 0.0 6.6e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA41847.1 - 4.3e-10 39.8 0.0 7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA41847.1 - 2e-07 30.7 0.3 5e-07 29.4 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KPA41847.1 - 0.00014 21.0 0.0 0.00026 20.2 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KPA41847.1 - 0.0015 17.7 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KPA41847.1 - 0.0036 16.8 0.4 0.0054 16.2 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KPA41847.1 - 0.076 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 3Beta_HSD PF01073.19 KPA41847.1 - 0.17 10.8 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family EamA PF00892.20 KPA41848.1 - 0.00017 21.8 7.3 0.00017 21.8 7.3 2.3 2 0 0 2 2 2 2 EamA-like transporter family MBOAT PF03062.19 KPA41849.1 - 8.9e-47 160.1 4.0 8.9e-47 160.1 4.0 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CPBP PF02517.16 KPA41851.1 - 3.1e-16 59.5 12.0 7.5e-16 58.3 7.9 2.9 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease MMM1 PF10296.9 KPA41852.1 - 1.9e-138 461.0 0.0 6.2e-137 456.1 0.0 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 GIDA PF01134.22 KPA41853.1 - 4.1e-156 520.0 0.0 6.2e-156 519.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Sec1 PF00995.23 KPA41853.1 - 8.3e-134 447.9 0.1 1.1e-133 447.5 0.1 1.2 1 0 0 1 1 1 1 Sec1 family GIDA_assoc PF13932.6 KPA41853.1 - 8.2e-64 215.6 0.1 1.7e-63 214.6 0.1 1.5 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KPA41853.1 - 5.7e-06 25.9 0.2 9e-06 25.3 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA41853.1 - 9.7e-06 25.0 0.0 2.3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPA41853.1 - 0.00062 19.0 2.3 0.00062 19.0 2.3 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KPA41853.1 - 0.0034 16.7 0.1 0.007 15.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KPA41853.1 - 0.016 13.9 2.0 0.091 11.4 1.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 KPA41853.1 - 0.13 12.8 0.2 0.92 10.1 0.2 2.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KPA41853.1 - 0.15 12.5 0.0 0.57 10.7 0.0 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding CDP-OH_P_transf PF01066.21 KPA41854.1 - 8.7e-15 55.2 0.5 8.7e-15 55.2 0.5 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gti1_Pac2 PF09729.9 KPA41855.1 - 9.9e-59 198.5 0.0 1.5e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Gti1/Pac2 family Tyr-DNA_phospho PF06087.12 KPA41856.1 - 3.3e-80 270.1 0.0 6.5e-80 269.1 0.0 1.6 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KPA41856.1 - 8.4e-05 22.2 2.1 8.4e-05 22.2 2.1 2.7 3 0 0 3 3 3 1 Ubiquitin interaction motif PLDc_2 PF13091.6 KPA41856.1 - 0.00017 21.5 0.0 0.016 15.1 0.0 3.0 2 1 1 3 3 3 1 PLD-like domain PLDc PF00614.22 KPA41856.1 - 0.018 15.2 0.1 0.35 11.1 0.0 2.9 3 0 0 3 3 3 0 Phospholipase D Active site motif FAM60A PF15396.6 KPA41856.1 - 3.4 7.6 6.4 8.1 6.4 6.4 1.6 1 0 0 1 1 1 0 Protein Family FAM60A MDM10 PF12519.8 KPA41857.1 - 1.6e-164 548.2 0.0 8.2e-163 542.6 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KPA41857.1 - 0.0029 17.1 0.2 0.55 9.6 0.0 2.7 4 0 0 4 4 4 2 Eukaryotic porin Zip PF02535.22 KPA41858.1 - 8.6e-64 215.9 6.7 9.8e-64 215.7 6.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Ribosomal_S19e PF01090.19 KPA41859.1 - 1.2e-58 196.7 0.2 1.4e-58 196.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DUF3818 PF12825.7 KPA41861.1 - 6e-52 176.7 0.0 5.7e-38 130.8 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KPA41861.1 - 1e-42 145.2 0.0 1.8e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 PX-associated DUF4449 PF14613.6 KPA41862.1 - 6.4e-70 234.5 5.8 6.4e-70 234.5 5.8 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) YlqD PF11068.8 KPA41862.1 - 0.0087 16.4 6.3 0.0087 16.4 6.3 3.2 4 0 0 4 4 4 1 YlqD protein ExsD PF16806.5 KPA41862.1 - 0.0097 15.9 1.8 4.5 7.1 0.0 2.4 2 0 0 2 2 2 2 Antiactivator protein ExsD ChaB PF06150.12 KPA41862.1 - 0.075 13.6 3.9 0.47 11.1 3.9 2.4 1 0 0 1 1 1 0 ChaB P4Ha_N PF08336.11 KPA41862.1 - 0.38 10.8 7.6 0.26 11.3 0.6 2.8 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region JAB PF01398.21 KPA41863.1 - 9.2e-32 109.5 0.1 1.7e-31 108.6 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KPA41863.1 - 2.9e-23 82.6 1.3 5.2e-23 81.8 1.3 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KPA41863.1 - 7.8e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KPA41863.1 - 0.03 14.3 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) AP_endonuc_2 PF01261.24 KPA41863.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel U62_UL91 PF17442.2 KPA41863.1 - 0.19 11.7 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins CorA PF01544.18 KPA41865.1 - 0.00045 19.6 8.1 0.0013 18.2 8.1 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3942 PF13078.6 KPA41865.1 - 0.16 12.3 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) PspB PF06667.12 KPA41865.1 - 1.5 8.9 5.7 4.5 7.4 5.1 2.1 2 0 0 2 2 2 0 Phage shock protein B Glyco_hydro_61 PF03443.14 KPA41866.1 - 6.6e-65 218.9 0.5 8e-65 218.6 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF5624 PF18538.1 KPA41866.1 - 0.0022 18.1 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) Ribosomal_L32p PF01783.23 KPA41868.1 - 0.81 10.0 7.7 7.3 6.9 0.6 2.5 2 0 0 2 2 2 0 Ribosomal L32p protein family Sugar_tr PF00083.24 KPA41869.1 - 1.1e-72 245.4 17.5 1.2e-72 245.2 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA41869.1 - 5.8e-23 81.4 20.3 5.8e-23 81.4 20.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA41869.1 - 0.066 12.1 10.1 0.008 15.1 5.0 1.9 2 0 0 2 2 2 0 MFS_1 like family DB_JBP1 PF18526.1 KPA41869.1 - 0.18 11.7 0.2 0.32 10.9 0.2 1.3 1 0 0 1 1 1 0 Thymine dioxygenase JBP1 DNA-binding domain WD40 PF00400.32 KPA41871.1 - 2.3e-11 44.0 1.6 3.1 8.8 0.0 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA41871.1 - 0.032 14.5 0.0 18 5.7 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_12 PF13087.6 KPA41872.1 - 6e-38 130.5 0.0 1.1e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPA41872.1 - 1.4e-23 84.0 0.8 2.1e-22 80.2 0.8 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPA41872.1 - 3.6e-09 36.6 0.2 1.8e-06 27.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KPA41872.1 - 3.5e-08 33.9 0.1 2.9e-07 30.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KPA41872.1 - 3.1e-05 23.8 0.1 0.0035 17.1 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KPA41872.1 - 0.0037 17.0 0.0 0.01 15.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 KPA41872.1 - 0.0074 16.1 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KPA41872.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Fungal_trans PF04082.18 KPA41873.1 - 1.1e-20 73.8 0.6 1.8e-20 73.1 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41873.1 - 1.1e-07 31.8 12.9 2.1e-07 31.0 12.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brr6_like_C_C PF10104.9 KPA41874.1 - 5.8e-41 139.4 3.0 7.5e-41 139.0 3.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Ribosomal_L24e PF01246.20 KPA41874.1 - 0.014 15.6 0.1 0.03 14.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L24e Med26 PF08711.11 KPA41875.1 - 7.8e-12 45.0 0.0 1.9e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Selenoprotein_S PF06936.11 KPA41876.1 - 0.1 12.4 0.8 0.12 12.1 0.8 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Pkinase PF00069.25 KPA41877.1 - 1.2e-41 142.8 0.1 7.5e-23 81.2 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA41877.1 - 9.2e-15 54.6 0.3 6.2e-10 38.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase zinc_ribbon_10 PF10058.9 KPA41878.1 - 1.3e-19 69.6 0.1 2.2e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF1664 PF07889.12 KPA41878.1 - 0.042 13.9 0.2 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TcdB_N PF12918.7 KPA41878.1 - 0.084 13.2 1.3 13 6.2 0.2 3.0 2 1 1 3 3 3 0 TcdB toxin N-terminal helical domain HalOD2 PF18547.1 KPA41878.1 - 1.2 9.1 3.5 27 4.8 0.1 2.4 2 0 0 2 2 2 0 Halobacterial output domain 2 GRIP PF01465.20 KPA41879.1 - 3.1e-15 55.8 0.1 8.2e-15 54.4 0.1 1.8 1 0 0 1 1 1 1 GRIP domain DHR10 PF18595.1 KPA41879.1 - 5.7e-05 23.1 173.9 9.1e-05 22.5 19.4 11.0 7 3 4 11 11 11 3 Designed helical repeat protein 10 domain GAS PF13851.6 KPA41879.1 - 9.5e-05 21.8 159.9 0.032 13.6 20.6 8.9 3 2 3 8 8 8 7 Growth-arrest specific micro-tubule binding DUF3800 PF12686.7 KPA41879.1 - 0.00047 20.8 0.0 13 6.4 0.0 5.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3800) Phage_GP20 PF06810.11 KPA41879.1 - 0.00093 19.0 4.5 0.00093 19.0 4.5 11.4 3 2 8 11 11 11 4 Phage minor structural protein GP20 ADIP PF11559.8 KPA41879.1 - 0.0017 18.5 2.5 0.0017 18.5 2.5 11.7 3 2 9 12 12 10 1 Afadin- and alpha -actinin-Binding MscS_porin PF12795.7 KPA41879.1 - 0.0021 17.6 26.2 0.0021 17.6 26.2 7.1 4 1 2 7 7 7 1 Mechanosensitive ion channel porin domain DUF4047 PF13256.6 KPA41879.1 - 0.0054 16.9 1.7 0.0054 16.9 1.7 8.2 4 3 6 11 11 11 1 Domain of unknown function (DUF4047) Bacillus_HBL PF05791.11 KPA41879.1 - 0.0095 15.8 4.7 0.0095 15.8 4.7 8.9 5 2 4 9 9 9 1 Bacillus haemolytic enterotoxin (HBL) DUF4201 PF13870.6 KPA41879.1 - 0.021 14.6 0.6 0.021 14.6 0.6 9.5 3 2 6 9 9 9 0 Domain of unknown function (DUF4201) TSC22 PF01166.18 KPA41879.1 - 0.025 14.9 0.8 0.025 14.9 0.8 11.1 10 2 2 12 12 11 0 TSC-22/dip/bun family APG6_N PF17675.1 KPA41879.1 - 0.061 13.9 195.7 0.17 12.4 18.3 11.6 3 2 8 12 12 11 0 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 KPA41879.1 - 0.096 12.7 0.2 0.096 12.7 0.2 8.9 5 3 5 10 10 10 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 KPA41879.1 - 0.1 12.6 166.0 0.14 12.2 21.8 9.6 4 3 5 9 9 9 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KPA41879.1 - 0.15 10.9 167.4 0.18 10.6 20.8 7.7 2 2 3 7 7 7 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KPA41879.1 - 1.1 9.2 172.4 0.056 13.5 23.0 9.1 3 2 6 9 9 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.11 KPA41879.1 - 7.7 5.3 164.2 0.19 10.6 17.1 6.9 2 2 5 7 7 7 0 Protein of unknown function (DUF812) Filament PF00038.21 KPA41879.1 - 8.1 5.9 144.6 2.9 7.4 6.2 7.8 2 1 4 6 6 6 0 Intermediate filament protein adh_short PF00106.25 KPA41880.1 - 7.7e-42 143.0 0.9 1.4e-41 142.2 0.9 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA41880.1 - 3.4e-40 138.1 1.0 8e-40 136.8 1.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA41880.1 - 1.3e-07 31.7 1.6 1.1e-06 28.7 1.6 2.2 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KPA41880.1 - 0.0048 16.9 0.0 0.0086 16.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 KPA41880.1 - 0.0061 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 KPA41880.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KPA41880.1 - 0.081 12.3 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SWIRM PF04433.17 KPA41881.1 - 3.8e-15 56.0 0.2 9.6e-14 51.5 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain F-box-like PF12937.7 KPA41882.1 - 8.8e-10 38.3 0.8 1.7e-09 37.4 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA41882.1 - 4.9e-07 29.5 2.3 8.6e-07 28.7 2.3 1.4 1 0 0 1 1 1 1 F-box domain DUF1691 PF07950.11 KPA41883.1 - 1e-39 135.5 6.0 9.4e-34 116.4 4.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.8 KPA41884.1 - 4.1e-06 26.9 2.1 6.7e-06 26.2 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPA41884.1 - 0.0013 19.1 0.4 0.0021 18.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KPA41884.1 - 0.12 13.2 0.2 0.24 12.4 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA41884.1 - 0.16 12.5 0.6 0.27 11.7 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-DBF PF07535.12 KPA41884.1 - 0.64 10.2 2.8 1.1 9.4 2.8 1.4 1 0 0 1 1 1 0 DBF zinc finger Fungal_trans PF04082.18 KPA41885.1 - 9.7e-17 60.9 0.5 6.4e-15 54.9 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41885.1 - 4e-08 33.2 12.7 9.6e-08 32.0 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.23 KPA41886.1 - 7e-84 281.7 31.9 3.8e-49 167.8 11.8 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA41886.1 - 2.6e-67 225.5 0.0 9.8e-33 113.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPA41886.1 - 1.4e-13 50.8 2.0 5.7e-05 22.7 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KPA41886.1 - 3.6e-08 34.0 0.1 0.00095 19.6 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KPA41886.1 - 5.6e-08 32.4 0.0 0.016 14.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KPA41886.1 - 3.9e-07 30.4 0.9 0.029 14.7 0.1 3.7 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KPA41886.1 - 1.6e-06 28.1 0.0 0.086 12.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KPA41886.1 - 2.4e-06 26.6 0.1 0.017 14.0 0.0 2.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 KPA41886.1 - 2.5e-05 24.1 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 KPA41886.1 - 6.8e-05 23.0 2.3 0.48 10.7 0.2 4.4 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KPA41886.1 - 0.00036 20.2 0.1 1.4 8.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 KPA41886.1 - 0.00037 20.5 0.2 0.77 9.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KPA41886.1 - 0.00061 19.1 0.2 0.62 9.3 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_30 PF13604.6 KPA41886.1 - 0.00088 19.0 4.5 0.65 9.7 0.4 4.0 4 1 0 4 4 4 2 AAA domain G-alpha PF00503.20 KPA41886.1 - 0.00095 18.4 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 KPA41886.1 - 0.001 18.9 0.0 1 9.1 0.0 3.4 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KPA41886.1 - 0.0033 17.7 0.2 0.78 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPA41886.1 - 0.0071 16.9 0.0 7 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KPA41886.1 - 0.0072 16.4 0.2 2.1 8.4 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 KPA41886.1 - 0.0074 16.8 0.0 6.4 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KPA41886.1 - 0.0093 16.1 0.1 5.3 7.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 KPA41886.1 - 0.014 15.4 0.1 0.99 9.3 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_14 PF13173.6 KPA41886.1 - 0.015 15.3 0.0 5.7 7.0 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_7 PF12775.7 KPA41886.1 - 0.019 14.5 0.0 1.7 8.1 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KPA41886.1 - 0.034 14.2 0.0 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KPA41886.1 - 0.12 12.8 0.0 7 7.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase PRK PF00485.18 KPA41886.1 - 0.14 11.9 0.2 6.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family VirE PF05272.11 KPA41886.1 - 0.16 11.6 0.0 8.1 6.1 0.0 2.2 2 0 0 2 2 2 0 Virulence-associated protein E AAA PF00004.29 KPA41886.1 - 0.2 12.1 2.0 41 4.6 0.2 4.0 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KPA41886.1 - 0.32 10.7 1.3 7.6 6.2 0.1 2.7 3 0 0 3 3 2 0 AAA domain RAC_head PF16717.5 KPA41887.1 - 9.2e-31 106.7 2.5 9.2e-31 106.7 2.5 4.1 3 2 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KPA41887.1 - 1e-19 70.4 1.3 6.1e-19 67.9 1.3 2.5 1 0 0 1 1 1 1 DnaJ domain V_ATPase_I PF01496.19 KPA41887.1 - 1.3 6.8 9.8 2.4 6.0 9.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ISG65-75 PF11727.8 KPA41887.1 - 3.3 6.9 25.3 7.2 5.8 25.3 1.6 1 0 0 1 1 1 0 Invariant surface glycoprotein Complex1_LYR PF05347.15 KPA41888.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KPA41888.1 - 0.033 15.0 0.1 0.039 14.7 0.1 1.1 1 0 0 1 1 1 0 Complex1_LYR-like RRM_1 PF00076.22 KPA41889.1 - 2.7e-10 39.9 0.0 4.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPA41889.1 - 0.002 18.1 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KPA41889.1 - 0.0023 17.9 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif RRM_occluded PF16842.5 KPA41889.1 - 0.0078 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Sterol_MT_C PF08498.10 KPA41890.1 - 7.1e-29 99.9 0.4 1.2e-28 99.2 0.4 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KPA41890.1 - 4.5e-21 75.3 0.0 8.5e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA41890.1 - 2.7e-19 69.7 0.0 5.5e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA41890.1 - 1.3e-17 64.0 0.0 2e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KPA41890.1 - 6.9e-11 41.9 0.1 9.6e-11 41.5 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KPA41890.1 - 7.6e-11 42.1 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA41890.1 - 1e-10 41.3 0.0 1.8e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KPA41890.1 - 2e-10 41.3 0.0 4.3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KPA41890.1 - 0.00029 20.6 0.0 0.00046 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.16 KPA41890.1 - 0.00059 18.5 0.0 0.0008 18.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 KPA41890.1 - 0.00096 18.8 0.0 0.0028 17.3 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW PrmA PF06325.13 KPA41890.1 - 0.0014 18.1 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KPA41890.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 KPA41890.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KPA41890.1 - 0.0027 16.8 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 KPA41890.1 - 0.0062 15.9 0.0 0.0098 15.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Hormone_3 PF00159.18 KPA41890.1 - 0.037 14.1 0.8 0.098 12.7 0.8 1.8 1 0 0 1 1 1 0 Pancreatic hormone peptide TehB PF03848.14 KPA41890.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KPA41890.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Transket_pyr PF02779.24 KPA41891.1 - 2.7e-46 157.5 0.0 4.2e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KPA41891.1 - 5.4e-37 126.4 0.0 1.7e-36 124.8 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DSHCT PF08148.12 KPA41892.1 - 5.4e-52 175.8 0.3 1.1e-51 174.7 0.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KPA41892.1 - 6.7e-41 139.3 0.0 5.2e-40 136.4 0.0 2.3 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KPA41892.1 - 3e-28 99.5 0.1 5.2e-28 98.7 0.1 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KPA41892.1 - 2.3e-18 66.6 0.0 8.3e-18 64.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA41892.1 - 3.2e-06 27.5 0.0 1.3e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA41892.1 - 5.4e-05 23.3 0.2 0.00021 21.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cut8 PF08559.10 KPA41892.1 - 0.037 13.6 0.1 0.088 12.4 0.1 1.6 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein SNAD4 PF18750.1 KPA41892.1 - 0.082 13.0 0.5 0.19 11.8 0.2 1.8 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 AAA_22 PF13401.6 KPA41892.1 - 0.16 12.2 0.1 0.9 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Snf7 PF03357.21 KPA41893.1 - 1.3e-05 24.9 27.2 1.3e-05 24.9 27.2 1.5 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.14 KPA41893.1 - 0.0001 22.3 5.1 0.00015 21.7 5.1 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF4829 PF16111.5 KPA41893.1 - 0.21 12.4 2.8 0.48 11.2 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4829) CEL_III_C PF18054.1 KPA41893.1 - 0.63 10.1 7.0 0.98 9.5 7.0 1.4 1 0 0 1 1 1 0 CEL-III C-terminal ASL_C PF08328.11 KPA41893.1 - 0.85 9.7 9.1 0.37 10.9 3.9 2.5 1 1 2 3 3 3 0 Adenylosuccinate lyase C-terminal bZIP_2 PF07716.15 KPA41894.1 - 1.1e-06 28.6 20.8 2.4e-06 27.5 20.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KPA41894.1 - 0.0002 21.4 18.7 0.00049 20.1 18.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KPA41894.1 - 0.00043 20.7 13.9 0.00087 19.8 13.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Tropomyosin_1 PF12718.7 KPA41894.1 - 0.025 14.7 10.8 0.053 13.7 10.8 1.5 1 0 0 1 1 1 0 Tropomyosin like TMEM247 PF15444.6 KPA41894.1 - 0.29 11.1 4.3 0.49 10.4 4.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 DUF3450 PF11932.8 KPA41894.1 - 0.5 9.6 7.8 0.8 9.0 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.8 KPA41894.1 - 0.78 9.8 10.6 1.3 9.1 10.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Adeno_E3_15_3 PF03307.14 KPA41894.1 - 0.88 9.5 2.7 1.8 8.5 2.7 1.5 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region APG6_N PF17675.1 KPA41894.1 - 0.94 10.0 10.8 1.8 9.1 10.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 KPA41894.1 - 1.8 7.8 5.8 2.8 7.2 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 KPA41894.1 - 6.5 6.8 8.3 12 5.9 8.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Swi3 PF07962.12 KPA41895.1 - 1.1e-31 108.7 0.2 2.1e-31 107.8 0.2 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Nnf1 PF03980.14 KPA41895.1 - 3 8.3 6.7 2.4e+02 2.1 6.7 2.8 1 1 0 1 1 1 0 Nnf1 NADH-u_ox-rdase PF10785.9 KPA41896.1 - 5.6e-29 100.6 0.2 1.1e-28 99.7 0.2 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KPA41896.1 - 1.1e-24 86.2 0.1 1.5e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DIOX_N PF14226.6 KPA41897.1 - 0.00036 21.3 0.0 0.00072 20.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPA41897.1 - 0.00056 20.4 0.0 0.00094 19.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Xan_ur_permease PF00860.20 KPA41898.1 - 9e-27 93.8 27.2 1.9e-16 59.8 11.3 2.8 3 0 0 3 3 3 2 Permease family zf-CCCH PF00642.24 KPA41900.1 - 0.0012 18.7 0.7 0.0023 17.8 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.9 KPA41900.1 - 0.037 13.8 4.1 0.069 12.9 4.1 1.5 1 0 0 1 1 1 0 Putative zinc-finger domain Myosin_head PF00063.21 KPA41901.1 - 3.6e-268 891.4 0.1 9.3e-268 890.0 0.1 1.8 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KPA41901.1 - 1e-12 47.6 0.1 2.5e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KPA41901.1 - 5.6e-10 37.8 277.2 5.4e-08 31.2 126.7 5.0 1 1 1 2 2 2 1 Myosin tail AAA_22 PF13401.6 KPA41901.1 - 0.011 16.0 0.0 0.011 16.0 0.0 4.9 5 0 0 5 5 5 0 AAA domain PKcGMP_CC PF16808.5 KPA41901.1 - 0.12 12.3 0.0 0.12 12.3 0.0 9.2 10 0 0 10 10 10 0 Coiled-coil N-terminus of cGMP-dependent protein kinase AAA_19 PF13245.6 KPA41901.1 - 0.12 12.7 3.7 1.1 9.6 0.0 3.3 2 0 0 2 2 2 0 AAA domain UDPG_MGDP_dh_N PF03721.14 KPA41901.1 - 0.32 10.5 3.1 0.91 9.1 3.1 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Phage_tail_NK PF16532.5 KPA41901.1 - 2.8 7.5 5.4 11 5.6 0.0 3.0 3 0 0 3 3 3 0 Sf6-type phage tail needle knob or tip of some Caudovirales Arc_PepC_II PF06847.11 KPA41901.1 - 9.7 6.8 9.5 51 4.5 0.0 5.2 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II Pex14_N PF04695.13 KPA41902.1 - 0.06 14.0 3.1 0.14 12.8 3.1 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RdRP PF05183.12 KPA41904.1 - 1.1e-184 615.4 0.0 2.1e-184 614.5 0.0 1.4 2 0 0 2 2 2 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KPA41904.1 - 0.0015 18.3 0.0 0.02 14.7 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.19 KPA41905.1 - 5.5e-61 206.4 0.1 1.1e-60 205.3 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KPA41905.1 - 3.7e-33 114.2 0.0 7.1e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Ribosomal_S4e PF00900.20 KPA41906.1 - 9.2e-37 124.8 0.2 2.1e-36 123.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KPA41906.1 - 3.5e-24 84.2 0.0 5.8e-24 83.5 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KPA41906.1 - 1.6e-18 66.5 4.6 2.9e-18 65.7 4.6 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 KPA41906.1 - 7.1e-06 25.8 5.5 7.1e-06 25.8 5.5 3.3 4 0 0 4 4 4 1 KOW motif S4 PF01479.25 KPA41906.1 - 1.8e-05 24.3 0.0 3.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain Sipho_tail PF05709.11 KPA41906.1 - 0.052 13.0 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Phage tail protein SH3_18 PF18354.1 KPA41906.1 - 0.11 12.6 0.1 2.8 8.0 0.0 2.6 3 0 0 3 3 3 0 CarS bacterial SH3 domain Myb_DNA-binding PF00249.31 KPA41907.1 - 9.8e-16 57.7 0.2 1.2e-08 34.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPA41907.1 - 2.9e-09 37.1 0.0 0.00014 22.1 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KPA41907.1 - 1.6e-07 31.3 0.1 0.00055 20.0 0.0 2.6 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 KPA41907.1 - 0.034 14.3 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 CALM_bind PF16025.5 KPA41907.1 - 0.091 13.2 0.0 0.4 11.2 0.0 2.2 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Lyase_1 PF00206.20 KPA41908.1 - 2e-111 372.3 0.0 2.9e-111 371.8 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KPA41908.1 - 3.9e-22 78.4 0.1 1.1e-21 77.0 0.1 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Myb_DNA-binding PF00249.31 KPA41910.1 - 0.002 18.3 0.1 0.0049 17.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPA41910.1 - 0.0037 17.5 0.1 0.01 16.1 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KPA41910.1 - 0.031 14.4 0.1 0.069 13.3 0.1 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Septin PF00735.18 KPA41911.1 - 5.1e-30 104.7 0.1 1.7e-18 66.9 0.2 3.1 2 1 0 2 2 2 2 Septin G-alpha PF00503.20 KPA41911.1 - 0.015 14.5 0.0 0.041 13.1 0.0 1.6 1 1 1 2 2 2 0 G-protein alpha subunit AAA_15 PF13175.6 KPA41911.1 - 0.037 13.8 0.0 0.068 12.9 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KPA41911.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3313 PF11769.8 KPA41911.1 - 0.075 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) ABC1 PF03109.16 KPA41912.1 - 7.4e-22 77.7 0.0 1.4e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KPA41912.1 - 0.0015 18.5 0.0 0.0044 17.0 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Nse4_C PF08743.10 KPA41912.1 - 0.031 14.5 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 Nse4 C-terminal Pkinase PF00069.25 KPA41912.1 - 0.11 11.9 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain SUR7 PF06687.12 KPA41913.1 - 9.6e-26 90.7 9.9 1.2e-25 90.4 9.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family CDP-OH_P_transf PF01066.21 KPA41915.1 - 1.4e-16 61.0 0.1 1.4e-16 61.0 0.1 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PAP1 PF08601.10 KPA41916.1 - 4.1e-08 33.3 6.0 4e-06 26.8 0.0 2.3 2 1 0 2 2 2 2 Transcription factor PAP1 bZIP_1 PF00170.21 KPA41916.1 - 2.8e-07 30.5 12.0 4.3e-07 29.9 12.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KPA41916.1 - 0.0025 18.3 8.4 0.0045 17.5 8.4 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor SHE3 PF17078.5 KPA41916.1 - 0.0027 17.5 2.9 0.0037 17.0 2.9 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 TSKS PF15358.6 KPA41916.1 - 0.013 13.9 2.0 1.3 7.3 0.9 2.1 2 0 0 2 2 2 0 Testis-specific serine kinase substrate Atg14 PF10186.9 KPA41916.1 - 0.04 13.0 0.9 0.052 12.6 0.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 KPA41916.1 - 0.15 9.9 0.3 0.19 9.6 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 KPA41916.1 - 0.17 11.9 8.1 0.33 11.0 8.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 KPA41916.1 - 1.1 9.3 14.8 23 5.2 14.8 2.2 1 1 0 1 1 1 0 Basic region leucine zipper M PF02370.16 KPA41916.1 - 2.4 9.0 5.3 0.53 11.0 1.2 2.1 2 0 0 2 2 2 0 M protein repeat Raptor_N PF14538.6 KPA41918.1 - 3.1e-64 215.4 0.0 5.7e-64 214.5 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain ANAPC4_WD40 PF12894.7 KPA41918.1 - 5.5e-07 29.8 0.0 0.99 9.7 0.1 4.7 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KPA41918.1 - 1.8e-06 28.0 0.1 0.04 13.9 0.1 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 KPA41918.1 - 6.5e-05 23.6 7.5 7.2 7.7 0.1 5.9 5 1 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.6 KPA41918.1 - 0.00023 21.5 0.3 0.31 11.5 0.0 4.1 4 0 0 4 4 4 1 HEAT repeats Atx10homo_assoc PF09759.9 KPA41918.1 - 0.00066 19.7 0.5 0.0013 18.8 0.5 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 KPA41918.1 - 0.0061 16.7 3.3 1.8 9.1 0.1 4.8 6 0 0 6 6 6 1 HEAT repeat Nup160 PF11715.8 KPA41918.1 - 0.062 11.9 0.1 0.24 10.0 0.1 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Kelch_4 PF13418.6 KPA41919.1 - 2.9e-31 107.2 8.8 2.6e-05 24.1 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KPA41919.1 - 1e-29 102.0 3.8 9.4e-07 28.7 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KPA41919.1 - 3.9e-28 97.1 12.6 3.8e-06 27.0 0.2 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KPA41919.1 - 2.5e-27 94.2 6.4 1.5e-08 34.6 0.4 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 KPA41919.1 - 5.3e-27 93.1 4.6 1.7e-09 37.1 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KPA41919.1 - 5.9e-16 57.7 13.2 6.3e-05 22.8 0.4 6.6 6 1 0 6 6 6 5 Kelch motif Pox_A_type_inc PF04508.12 KPA41919.1 - 0.00068 19.4 9.3 3.3 7.7 0.1 5.5 4 0 0 4 4 4 3 Viral A-type inclusion protein repeat Cnn_1N PF07989.11 KPA41919.1 - 0.0012 18.9 3.6 0.0012 18.9 3.6 7.3 5 2 3 8 8 8 2 Centrosomin N-terminal motif 1 GAS PF13851.6 KPA41919.1 - 4.2 6.7 77.5 0.9 8.9 17.6 4.9 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding SMC_N PF02463.19 KPA41920.1 - 1.7e-26 93.0 0.1 2.4e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPA41920.1 - 2.4e-11 44.5 25.2 2.4e-11 44.5 25.2 5.2 2 2 0 3 3 2 1 AAA domain AAA_15 PF13175.6 KPA41920.1 - 4.8e-09 36.4 0.2 2.1e-05 24.4 0.0 3.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KPA41920.1 - 1.9e-05 24.6 9.6 0.033 14.0 0.1 3.8 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Baculo_PEP_C PF04513.12 KPA41920.1 - 0.0034 17.4 13.5 0.85 9.6 0.0 4.9 5 0 0 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_29 PF13555.6 KPA41920.1 - 0.023 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KPA41920.1 - 0.032 14.7 0.0 0.032 14.7 0.0 4.0 4 1 0 4 4 3 0 ABC transporter AAA PF00004.29 KPA41920.1 - 0.16 12.4 1.3 0.75 10.2 0.2 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KPA41920.1 - 0.21 11.2 2.4 0.6 9.7 0.0 3.0 4 0 0 4 4 4 0 AAA domain AAA_27 PF13514.6 KPA41920.1 - 0.35 10.4 0.0 0.35 10.4 0.0 4.1 3 2 1 4 4 4 0 AAA domain DUF465 PF04325.13 KPA41920.1 - 2.1 8.4 18.6 0.13 12.3 2.0 4.7 3 1 1 4 4 4 0 Protein of unknown function (DUF465) Syntaxin-6_N PF09177.11 KPA41920.1 - 2.3 8.8 40.5 0.06 13.9 3.3 6.5 5 1 2 7 7 7 0 Syntaxin 6, N-terminal Sec34 PF04136.15 KPA41920.1 - 4.9 7.0 26.9 2.2 8.1 0.7 5.8 5 1 1 6 6 6 0 Sec34-like family Pkinase PF00069.25 KPA41921.1 - 5.3e-66 222.7 0.1 3.5e-65 220.0 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KPA41921.1 - 1.3e-40 137.8 0.5 2.8e-40 136.7 0.5 1.6 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KPA41921.1 - 4e-36 124.6 0.1 2.8e-35 121.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA41921.1 - 1.3e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KPA41921.1 - 0.0014 17.7 0.5 0.0026 16.8 0.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KPA41921.1 - 0.0075 15.6 1.5 0.011 15.1 0.1 2.0 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KPA41921.1 - 1.5 8.3 7.0 0.2 11.2 0.2 2.6 3 0 0 3 3 3 0 Choline/ethanolamine kinase Malate_synthase PF01274.22 KPA41922.1 - 1.3e-227 756.3 0.0 1.4e-227 756.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase zf-C2H2 PF00096.26 KPA41923.1 - 5.1e-10 39.2 12.7 0.00014 22.1 4.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA41923.1 - 5.5e-09 36.1 10.6 0.0005 20.7 0.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPA41923.1 - 5.1e-06 26.7 1.7 5.1e-06 26.7 1.7 3.9 5 0 0 5 5 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KPA41923.1 - 0.00063 19.7 6.9 0.11 12.6 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger BolA PF01722.18 KPA41923.1 - 0.001 19.3 1.4 0.27 11.5 0.0 2.7 2 1 1 3 3 3 2 BolA-like protein zf-C2H2_jaz PF12171.8 KPA41923.1 - 0.075 13.3 3.1 0.22 11.9 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KPA41923.1 - 0.24 11.4 2.3 0.58 10.1 2.3 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KPA41923.1 - 0.33 10.8 6.0 2.5 7.9 0.6 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KPA41923.1 - 0.98 9.2 10.9 5.9 6.7 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-CHY PF05495.12 KPA41923.1 - 2.7 8.5 5.4 15 6.1 5.4 2.0 1 1 0 1 1 1 0 CHY zinc finger zf-AN1 PF01428.16 KPA41923.1 - 3.6 7.8 9.4 5 7.4 2.1 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HE PF16278.5 KPA41923.1 - 3.8 8.0 8.7 6 7.4 1.9 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Putative_PNPOx PF01243.20 KPA41924.1 - 2.1e-08 34.2 0.0 6.7e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 KPA41924.1 - 0.00016 22.0 0.0 0.00089 19.6 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.11 KPA41924.1 - 0.0086 16.3 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_1 PF00175.21 KPA41924.1 - 0.031 14.9 0.0 0.06 14.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain CTP_transf_like PF01467.26 KPA41925.1 - 9.2e-29 100.5 0.0 1.3e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Exo_endo_phos PF03372.23 KPA41926.1 - 0.0002 21.0 0.0 0.00052 19.6 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KPA41926.1 - 0.12 12.2 0.3 0.44 10.4 0.3 1.9 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF2461 PF09365.10 KPA41927.1 - 6e-79 264.8 0.2 7.7e-79 264.5 0.2 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) NOA36 PF06524.12 KPA41927.1 - 0.29 10.4 17.1 0.51 9.6 1.7 2.2 2 0 0 2 2 2 0 NOA36 protein AT_hook PF02178.19 KPA41927.1 - 2.5 8.3 9.0 0.16 11.9 3.0 2.4 2 0 0 2 2 2 0 AT hook motif Cwf_Cwc_15 PF04889.12 KPA41927.1 - 2.7 7.7 18.2 3 7.5 9.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Lipase_GDSL_2 PF13472.6 KPA41929.1 - 5.3e-08 33.5 0.0 6.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA41929.1 - 0.0017 18.3 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HSP70 PF00012.20 KPA41930.1 - 2.4e-262 871.5 14.4 2.7e-262 871.3 14.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KPA41930.1 - 2.4e-19 69.3 2.7 4.3e-18 65.2 0.5 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KPA41930.1 - 0.00059 19.6 0.0 0.0035 17.1 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KPA41930.1 - 0.0043 17.4 4.5 1.6 9.2 0.5 3.5 3 1 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 KPA41930.1 - 0.012 14.7 0.3 0.4 9.6 0.2 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KPA41930.1 - 0.042 13.1 1.9 0.29 10.4 0.0 2.8 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase Borrelia_orfA PF02414.15 KPA41930.1 - 2.6 7.6 14.0 0.12 12.0 4.6 2.4 2 0 0 2 2 2 0 Borrelia ORF-A DUF722 PF05263.11 KPA41931.1 - 0.12 12.6 0.8 0.22 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF722) AAA_12 PF13087.6 KPA41933.1 - 4.2e-09 36.3 0.0 5.8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KPA41935.1 - 3.8e-47 160.4 0.0 8.5e-47 159.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KPA41935.1 - 1.8e-26 92.2 1.1 4.1e-26 91.1 1.1 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 KPA41935.1 - 6.6e-08 32.8 0.0 6.6e-08 32.8 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KPA41935.1 - 7.8e-08 32.4 0.1 1.8e-06 28.0 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KPA41935.1 - 5.1e-05 23.6 0.4 0.00025 21.3 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Roc PF08477.13 KPA41935.1 - 0.0015 18.7 0.1 0.44 10.8 0.0 3.0 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KPA41935.1 - 0.017 14.4 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 KPA41935.1 - 0.046 13.2 2.7 1.6 8.1 0.1 3.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Arf PF00025.21 KPA41935.1 - 0.077 12.5 0.0 12 5.3 0.0 2.5 1 1 1 2 2 2 0 ADP-ribosylation factor family FeoB_N PF02421.18 KPA41935.1 - 0.14 11.7 0.1 3.2 7.3 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B NDC10_II PF16787.5 KPA41935.1 - 0.31 10.0 0.9 0.5 9.4 0.9 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Dynamin_N PF00350.23 KPA41935.1 - 0.73 9.9 2.8 5.7 7.0 0.0 3.2 2 1 1 3 3 3 0 Dynamin family CDV3 PF15359.6 KPA41935.1 - 1.1 9.7 10.3 1.9 9.0 8.5 2.2 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Cpn60_TCP1 PF00118.24 KPA41936.1 - 2.1e-156 521.4 5.6 2.4e-156 521.2 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans_2 PF11951.8 KPA41937.1 - 0.00013 20.9 0.1 0.00022 20.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KPA41938.1 - 6.1e-59 199.1 8.0 6.1e-59 199.1 8.0 1.7 1 1 1 2 2 2 1 RTA1 like protein zf-CHY PF05495.12 KPA41939.1 - 6.5e-10 39.4 10.6 6.5e-10 39.4 10.6 3.5 2 1 1 3 3 3 1 CHY zinc finger RWD PF05773.22 KPA41939.1 - 0.00042 20.6 0.5 0.0073 16.6 0.0 2.4 2 0 0 2 2 2 1 RWD domain Mu-like_Com PF10122.9 KPA41939.1 - 0.038 13.4 0.1 0.038 13.4 0.1 2.5 3 0 0 3 3 3 0 Mu-like prophage protein Com zf-trcl PF13451.6 KPA41939.1 - 0.18 11.7 0.1 0.18 11.7 0.1 4.0 6 0 0 6 6 6 0 Probable zinc-ribbon domain ATG16 PF08614.11 KPA41939.1 - 2 8.6 8.5 0.24 11.6 0.8 2.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) zf-RanBP PF00641.18 KPA41939.1 - 4.4 6.7 8.6 9.5 5.6 0.2 3.2 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others MFS_1 PF07690.16 KPA41940.1 - 3.1e-34 118.5 47.8 4.3e-33 114.7 47.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA41940.1 - 1.3e-15 56.9 24.8 1.8e-15 56.4 24.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPA41940.1 - 1e-12 47.7 10.6 1e-12 47.7 10.6 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 KPA41940.1 - 0.00063 18.4 32.8 0.0097 14.5 1.3 3.6 3 1 0 3 3 3 2 MFS/sugar transport protein DUF1129 PF06570.11 KPA41940.1 - 7.8 5.9 18.7 0.37 10.3 1.8 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1129) LXG PF04740.12 KPA41942.1 - 0.055 13.2 6.7 0.053 13.2 2.7 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF848 PF05852.11 KPA41942.1 - 0.063 13.4 10.4 0.044 13.9 7.1 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) KASH_CCD PF14662.6 KPA41942.1 - 0.094 12.5 16.9 0.21 11.4 16.7 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF2508 PF10704.9 KPA41942.1 - 0.19 11.9 10.1 1.3 9.3 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2508) Syntaxin-6_N PF09177.11 KPA41942.1 - 0.21 12.1 11.5 0.42 11.2 6.9 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 KPA41942.1 - 0.31 10.3 5.9 0.56 9.5 5.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Caskin-tail PF16632.5 KPA41942.1 - 0.67 10.4 3.4 1.1 9.7 0.5 2.5 2 1 0 2 2 2 0 C-terminal region of Caskin Fib_alpha PF08702.10 KPA41942.1 - 0.74 10.0 9.7 24 5.1 0.0 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family UPF0449 PF15136.6 KPA41942.1 - 1.2 9.7 13.8 0.67 10.5 6.1 2.7 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 ECH_2 PF16113.5 KPA41942.1 - 6.2 6.2 8.0 6.1 6.2 7.3 1.3 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF1033 PF06279.11 KPA41943.1 - 0.32 11.2 2.8 0.66 10.2 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) PspA_IM30 PF04012.12 KPA41943.1 - 0.83 9.2 40.9 33 3.9 40.5 2.3 1 1 0 1 1 1 0 PspA/IM30 family DUF745 PF05335.13 KPA41943.1 - 2 8.1 37.5 0.25 11.1 11.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.9 KPA41943.1 - 2.6 8.0 42.6 0.079 13.0 18.7 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SecD-TM1 PF13721.6 KPA41943.1 - 4.5 7.8 9.2 0.57 10.7 0.8 2.5 2 1 0 2 2 2 0 SecD export protein N-terminal TM region IFT57 PF10498.9 KPA41943.1 - 5.7 5.8 26.2 0.75 8.7 6.8 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 PolyA_pol PF01743.20 KPA41943.1 - 8.1 6.9 12.1 0.97 9.9 3.9 2.8 1 1 2 3 3 3 0 Poly A polymerase head domain DUF3295 PF11702.8 KPA41944.1 - 3.2e-160 534.8 30.8 3.7e-159 531.3 30.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KPA41944.1 - 1.2e-12 47.4 1.4 2.4e-12 46.4 1.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PFK PF00365.20 KPA41945.1 - 3.1e-187 620.7 0.9 4.1e-103 344.6 1.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.19 KPA41945.1 - 0.019 14.7 0.7 0.046 13.5 0.7 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif TgMIC1 PF11476.8 KPA41945.1 - 0.1 12.4 0.8 0.76 9.5 0.1 2.4 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 DAGK_cat PF00781.24 KPA41945.1 - 0.13 11.9 0.0 1 9.0 0.0 2.5 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain SelP_N PF04592.14 KPA41946.1 - 6.9 6.0 7.7 13 5.1 7.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HEAT PF02985.22 KPA41947.1 - 9.2e-14 50.4 10.8 0.02 15.1 0.0 9.7 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.6 KPA41947.1 - 1.8e-10 41.1 8.5 2.9e-07 30.8 0.0 7.0 6 1 2 8 8 8 1 HEAT-like repeat IBN_N PF03810.19 KPA41947.1 - 2.4e-08 33.7 4.1 2.7e-07 30.4 0.9 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KPA41947.1 - 3.6e-08 33.7 11.1 0.0053 17.1 0.1 6.4 3 2 3 6 6 6 4 HEAT repeats CLASP_N PF12348.8 KPA41947.1 - 2.8e-05 23.8 3.5 1.6 8.3 0.1 5.5 2 2 1 5 5 5 1 CLASP N terminal DUF3385 PF11865.8 KPA41947.1 - 0.015 15.2 4.6 9.4 6.1 0.0 5.0 4 1 1 5 5 5 0 Domain of unknown function (DUF3385) NUC173 PF08161.12 KPA41947.1 - 0.03 14.0 3.5 26 4.4 0.0 4.4 5 1 0 5 5 5 0 NUC173 domain Guanylate_kin PF00625.21 KPA41947.1 - 0.035 13.8 0.1 0.092 12.4 0.1 1.7 1 0 0 1 1 1 0 Guanylate kinase Cse1 PF08506.10 KPA41947.1 - 0.041 12.7 0.0 0.41 9.4 0.0 2.4 2 0 0 2 2 2 0 Cse1 HEAT_PBS PF03130.16 KPA41947.1 - 0.12 13.1 0.1 1.3e+02 3.7 0.0 4.6 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Fungal_trans PF04082.18 KPA41948.1 - 1.1e-05 24.6 0.0 1.1e-05 24.6 0.0 1.9 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA41948.1 - 0.0012 18.9 6.9 0.0021 18.1 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAICAR_synt PF01259.18 KPA41949.1 - 6e-99 330.7 0.0 6.9e-99 330.5 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Aminotran_1_2 PF00155.21 KPA41950.1 - 1.4e-45 156.1 0.0 1.6e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KPA41950.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase 2OG-FeII_Oxy_3 PF13640.6 KPA41951.1 - 1.2e-06 29.4 0.0 3.9e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3876 PF12992.7 KPA41951.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) TP_methylase PF00590.20 KPA41952.1 - 7.5e-46 156.8 0.0 1.7e-45 155.6 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KPA41952.1 - 1.4e-12 47.9 0.0 2.7e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 KPA41952.1 - 4.9e-11 41.9 0.1 1.3e-10 40.5 0.1 1.8 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 KPA41952.1 - 1.9e-08 33.8 0.1 3.5e-07 29.8 0.1 2.3 1 1 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal SO_alpha_A3 PF17806.1 KPA41953.1 - 0.11 12.9 0.0 0.33 11.3 0.0 1.8 1 1 0 1 1 1 0 Sarcosine oxidase A3 domain TRP PF06011.12 KPA41955.1 - 7.7e-164 545.5 26.4 9.5e-164 545.1 26.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KPA41955.1 - 1.2e-40 139.1 0.3 2.1e-40 138.3 0.3 1.4 1 0 0 1 1 1 1 ML-like domain DUF3433 PF11915.8 KPA41956.1 - 1.3e-38 131.4 24.1 1.5e-21 76.7 3.8 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF4381 PF14316.6 KPA41956.1 - 3 8.1 4.8 13 6.1 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) SUR7 PF06687.12 KPA41958.1 - 1.7e-30 106.2 16.3 2.2e-30 105.9 16.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family ABC2_membrane_2 PF12679.7 KPA41958.1 - 7.8 5.7 15.0 1.9 7.7 10.3 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Paf67 PF10255.9 KPA41960.1 - 0.0044 16.1 0.0 0.0092 15.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 ANAPC3 PF12895.7 KPA41960.1 - 0.086 13.1 0.4 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MitMem_reg PF13012.6 KPA41960.1 - 0.097 13.1 0.1 0.95 9.9 0.0 2.5 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function TPR_2 PF07719.17 KPA41960.1 - 0.14 12.3 0.2 0.39 11.0 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1151 PF06625.11 KPA41960.1 - 0.19 11.7 0.8 0.37 10.7 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) zf-PHD-like PF15446.6 KPA41962.1 - 5.9e-71 237.5 14.5 1.8e-70 236.0 14.5 1.9 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KPA41962.1 - 9.6e-49 166.0 0.1 3.5e-48 164.1 0.0 1.9 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA41962.1 - 3e-18 66.2 0.1 1.1e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KPA41962.1 - 8.5e-08 31.7 2.6 3.7e-07 29.6 2.6 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KPA41962.1 - 6.1e-06 26.1 0.5 0.00012 21.9 0.6 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KPA41962.1 - 6.5e-05 22.7 6.2 6.5e-05 22.7 6.2 3.6 2 2 1 3 3 3 1 PHD-finger ResIII PF04851.15 KPA41962.1 - 0.00031 20.8 0.0 0.0012 18.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPA41962.1 - 0.019 14.7 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase PHD_2 PF13831.6 KPA41962.1 - 7.8 6.1 14.9 0.024 14.2 1.2 2.8 3 0 0 3 3 3 0 PHD-finger SpoU_methylase PF00588.19 KPA41963.1 - 1.7e-24 86.6 0.0 3.7e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KPA41963.1 - 1.3e-10 41.3 0.0 2.8e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding PRCC PF10253.9 KPA41964.1 - 0.34 11.7 7.7 0.066 14.0 3.8 1.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting GFA PF04828.14 KPA41965.1 - 1.7e-24 85.9 0.0 2.6e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KPA41965.1 - 0.43 10.6 4.0 2.2 8.4 0.3 2.4 2 1 0 2 2 2 0 Double zinc ribbon DUF1365 PF07103.11 KPA41966.1 - 1.2e-40 139.7 0.0 1.7e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) MBF1 PF08523.10 KPA41967.1 - 3.2e-23 82.0 1.6 6.3e-23 81.0 1.6 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KPA41967.1 - 2.1e-10 40.5 0.0 3.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KPA41967.1 - 0.0012 19.1 0.1 0.003 17.9 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain Coatomer_E PF04733.14 KPA41968.1 - 1.1e-64 218.6 5.3 1.3e-64 218.4 5.3 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KPA41968.1 - 1.3e-10 41.7 15.7 4.8e-05 23.8 1.7 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA41968.1 - 8.7e-08 32.3 0.2 0.069 13.4 0.5 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KPA41968.1 - 3.9e-07 30.3 7.5 0.0013 19.0 0.8 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA41968.1 - 1.1e-05 25.2 2.3 0.091 13.0 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KPA41968.1 - 1.5e-05 24.6 1.0 0.03 14.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KPA41968.1 - 4e-05 24.0 4.5 0.17 12.6 0.0 5.0 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPA41968.1 - 6.5e-05 23.5 11.3 0.02 15.5 0.8 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KPA41968.1 - 7.4e-05 23.2 14.3 0.05 14.4 1.2 5.7 7 1 0 7 7 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPA41968.1 - 0.00056 19.8 11.3 0.0047 16.9 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KPA41968.1 - 0.00068 18.9 4.6 0.19 10.9 3.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF5588 PF17826.1 KPA41968.1 - 0.0011 18.0 0.1 0.002 17.1 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5588) TPR_17 PF13431.6 KPA41968.1 - 0.0079 16.5 3.1 1.4 9.5 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KPA41968.1 - 0.0091 16.1 4.0 0.15 12.2 0.8 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KPA41968.1 - 0.011 15.4 1.2 0.011 15.4 1.2 3.8 5 0 0 5 5 5 0 TPR repeat NARP1 PF12569.8 KPA41968.1 - 0.11 11.4 4.0 4.4 6.1 0.6 2.5 1 1 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 KPA41968.1 - 0.12 12.5 9.2 3.4 7.9 0.1 5.5 6 1 1 7 7 6 0 Tetratricopeptide repeat Smr PF01713.21 KPA41968.1 - 0.14 12.5 0.4 3.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Smr domain TPR_4 PF07721.14 KPA41968.1 - 0.18 12.5 0.5 0.18 12.5 0.5 5.9 8 0 0 8 8 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KPA41968.1 - 1 9.4 4.0 13 5.9 0.2 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 Ribosomal_L44 PF00935.19 KPA41969.1 - 2e-36 124.3 12.5 4.1e-36 123.3 12.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L44 KorB PF08535.10 KPA41970.1 - 0.024 14.7 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 KorB domain Ureidogly_lyase PF04115.12 KPA41971.1 - 9.9e-55 185.2 0.0 1.2e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase RecQ5 PF06959.11 KPA41971.1 - 0.014 15.4 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) CDH-cyt PF16010.5 KPA41972.1 - 1.8e-15 57.1 0.0 2.8e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KPA41972.1 - 1.5e-06 28.4 7.4 1.5e-06 28.4 7.4 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KPA41972.1 - 0.0077 16.4 8.2 0.027 14.6 2.4 3.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) DUF2157 PF09925.9 KPA41972.1 - 0.057 13.2 8.9 0.19 11.5 9.0 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF2427 PF10348.9 KPA41972.1 - 0.11 12.3 6.7 0.064 13.0 2.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) PsbH PF00737.20 KPA41972.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.3 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein DUF1129 PF06570.11 KPA41972.1 - 1 8.8 4.5 0.56 9.7 2.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) PI-PLC-X PF00388.19 KPA41973.1 - 0.00048 19.7 0.0 0.0007 19.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DnaJ PF00226.31 KPA41974.1 - 2.2e-13 50.1 0.1 3.7e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.16 KPA41975.1 - 1.3e-29 103.2 32.1 1.3e-29 103.2 32.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA41975.1 - 3.4e-20 72.3 25.3 1.2e-17 63.9 8.8 2.8 2 1 1 3 3 3 3 Sugar (and other) transporter PC4 PF02229.16 KPA41976.1 - 4.5e-24 83.8 0.2 6.9e-24 83.2 0.2 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) ApoB100_C PF12491.8 KPA41976.1 - 0.21 11.6 0.0 0.37 10.8 0.0 1.5 1 1 0 1 1 1 0 Apolipoprotein B100 C terminal PXA PF02194.15 KPA41977.1 - 1.5e-32 113.1 0.1 3.1e-32 112.0 0.1 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KPA41977.1 - 2.9e-23 82.6 0.3 1.2e-22 80.6 0.1 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KPA41977.1 - 7.2e-06 26.0 0.0 3.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 PX domain DUF5305 PF17231.2 KPA41977.1 - 0.1 12.0 1.6 0.24 10.7 1.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Uds1 PF15456.6 KPA41978.1 - 6.5e-33 113.7 6.6 1.6e-32 112.4 6.6 1.7 1 0 0 1 1 1 1 Up-regulated During Septation Paramyxo_PNT PF14320.6 KPA41978.1 - 0.0015 17.7 0.3 0.0026 17.0 0.3 1.3 1 0 0 1 1 1 1 Phosphoprotein P region PNT disordered DUF5446 PF17522.2 KPA41978.1 - 0.13 12.4 0.3 9.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Stathmin PF00836.19 KPA41978.1 - 0.39 10.7 5.5 0.073 13.0 1.0 2.1 2 0 0 2 2 2 0 Stathmin family Med9 PF07544.13 KPA41978.1 - 3.1 7.9 5.9 7.9 6.6 0.9 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Peptidase_M1 PF01433.20 KPA41979.1 - 3.7e-43 147.6 1.2 5.6e-43 147.0 1.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KPA41979.1 - 4.6e-38 129.8 0.1 9.4e-38 128.8 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KPA41979.1 - 6e-32 111.3 0.2 5.6e-31 108.2 0.0 2.2 1 1 1 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KPA41979.1 - 0.0076 16.0 0.5 0.042 13.5 0.0 2.2 3 0 0 3 3 3 1 Peptidase MA superfamily TbpB_B_D PF01298.18 KPA41979.1 - 0.034 14.6 0.1 0.075 13.4 0.1 1.5 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Peptidase_M61 PF05299.12 KPA41979.1 - 6.7 7.1 6.2 9.3 6.7 2.2 2.9 3 1 0 3 3 3 0 M61 glycyl aminopeptidase DUF952 PF06108.12 KPA41980.1 - 7e-23 80.5 0.0 9.5e-23 80.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Kinesin PF00225.23 KPA41982.1 - 1.4e-111 372.7 0.0 1.4e-111 372.7 0.0 1.9 2 0 0 2 2 1 1 Kinesin motor domain DUF3694 PF12473.8 KPA41982.1 - 1.6e-48 165.3 0.0 6e-48 163.4 0.0 2.1 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KPA41982.1 - 1.7e-36 126.1 11.5 2.7e-31 109.1 0.3 3.9 2 1 0 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 KPA41982.1 - 1.1e-23 83.9 0.0 4e-23 82.0 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 KPA41982.1 - 3.1e-06 27.5 0.2 3.1e-06 27.5 0.2 2.8 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.29 KPA41982.1 - 0.00062 20.2 0.0 0.018 15.5 0.0 2.8 1 1 0 1 1 1 1 PH domain Arm-DNA-bind_5 PF17293.2 KPA41982.1 - 0.0084 16.5 0.3 0.0084 16.5 0.3 2.9 1 1 1 2 2 2 1 Arm DNA-binding domain Yop-YscD_cpl PF16697.5 KPA41982.1 - 0.018 15.3 0.0 0.077 13.3 0.0 2.1 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain YbbR PF07949.12 KPA41982.1 - 0.066 13.6 2.2 0.78 10.1 0.0 3.3 3 0 0 3 3 3 0 YbbR-like protein Exonuc_VII_L PF02601.15 KPA41982.1 - 0.18 11.3 7.4 0.3 10.6 6.0 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2894 PF11445.8 KPA41982.1 - 6.4 7.2 15.9 0.16 12.4 6.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) MMR1 PF08505.10 KPA41982.1 - 8.8 6.5 17.1 2.9 8.1 2.1 2.7 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Methyltransf_23 PF13489.6 KPA41983.1 - 2.2e-14 53.6 0.0 3.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA41983.1 - 4.8e-08 33.6 0.0 1.8e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA41983.1 - 1.7e-05 24.7 0.0 0.00021 21.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA41983.1 - 7.1e-05 23.5 0.0 0.00025 21.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA41983.1 - 0.0052 16.1 0.0 0.014 14.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KPA41983.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 KPA41983.1 - 0.039 14.6 0.0 0.078 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KPA41983.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 KPA41983.1 - 0.21 11.0 0.0 0.41 10.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KPA41983.1 - 0.23 11.0 0.0 0.52 9.8 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Cupin_5 PF06172.11 KPA41984.1 - 4.7e-48 162.9 0.0 5.8e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Peptidase_M48 PF01435.18 KPA41985.1 - 1.1e-37 129.7 0.0 1.9e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF3040 PF11239.8 KPA41985.1 - 0.23 11.7 0.9 7.1 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) RasGAP PF00616.19 KPA41986.1 - 1.2e-31 110.1 0.2 2.6e-28 99.2 0.1 3.0 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KPA41986.1 - 2.1e-08 34.4 0.1 5.5e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain XRN_M PF17846.1 KPA41987.1 - 9.1e-142 473.1 0.3 9.1e-142 473.1 0.3 2.4 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KPA41987.1 - 1.6e-99 332.3 0.0 2.3e-99 331.7 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_2 PF13696.6 KPA41987.1 - 0.071 12.9 3.0 0.18 11.6 3.0 1.7 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_head PF04869.14 KPA41988.1 - 2.2e-113 378.5 0.2 9.2e-112 373.2 0.0 2.5 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Methyltransf_25 PF13649.6 KPA41988.1 - 1.6e-12 47.9 0.0 1.2e-11 45.1 0.0 2.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KPA41988.1 - 2.7e-11 43.4 0.1 2.7e-11 43.4 0.1 3.1 4 0 0 4 4 3 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KPA41988.1 - 1.3e-10 41.3 0.0 8.7e-10 38.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA41988.1 - 1.3e-10 41.8 0.0 9.5e-10 39.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Uso1_p115_C PF04871.13 KPA41988.1 - 9.6e-10 38.9 26.7 9.6e-10 38.9 26.7 5.5 2 1 3 5 5 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Methyltransf_23 PF13489.6 KPA41988.1 - 4.7e-06 26.5 0.0 1.5e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KPA41988.1 - 1.1e-05 25.4 1.0 4.2e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KPA41988.1 - 2.8e-05 23.7 0.2 7.6e-05 22.3 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KPA41988.1 - 3.4e-05 24.5 0.0 0.00014 22.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KPA41988.1 - 0.00052 19.5 0.1 0.0017 17.8 0.0 1.8 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 KPA41988.1 - 0.0041 16.1 0.0 0.0041 16.1 0.0 2.5 2 1 0 2 2 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 KPA41988.1 - 0.0079 15.9 0.1 0.033 13.9 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 KPA41988.1 - 0.016 14.9 0.8 0.05 13.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical protein 95 PCMT PF01135.19 KPA41988.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) VirionAssem_T7 PF11653.8 KPA41988.1 - 0.79 10.3 4.9 1.6 9.3 1.2 2.8 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein Filament PF00038.21 KPA41988.1 - 9 5.8 73.0 0.34 10.5 53.1 3.5 3 1 2 5 5 5 0 Intermediate filament protein OPT PF03169.15 KPA41989.1 - 3e-145 485.3 26.8 3.4e-145 485.1 26.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 KPA41989.1 - 0.18 11.9 5.8 0.21 11.6 0.2 3.0 2 0 0 2 2 2 0 Bacteriophage P21 holin S Rav1p_C PF12234.8 KPA41990.1 - 1.3e-280 932.4 0.0 1.5e-280 932.1 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal Glyco_hydro_32N PF00251.20 KPA41990.1 - 0.12 11.9 0.0 0.39 10.2 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain WD40 PF00400.32 KPA41990.1 - 0.52 11.3 11.6 8.8 7.4 0.0 5.7 6 0 0 6 6 6 0 WD domain, G-beta repeat Sfi1 PF08457.10 KPA41991.1 - 4.6e-25 88.2 86.4 4e-19 68.6 30.9 2.8 2 1 1 3 3 3 2 Sfi1 spindle body protein tRNA-synt_1 PF00133.22 KPA41992.1 - 1.9e-222 739.8 0.2 4.8e-222 738.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KPA41992.1 - 1.6e-23 83.3 0.0 3.9e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KPA41992.1 - 1.1e-14 54.0 0.2 2.6e-05 23.2 0.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KPA41992.1 - 0.013 14.8 0.0 0.051 12.9 0.0 2.0 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Mo25 PF08569.11 KPA41993.1 - 6.6e-129 430.0 0.0 7.4e-129 429.8 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Sec7_N PF12783.7 KPA41993.1 - 0.052 13.5 0.8 2.3 8.1 0.0 2.9 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SWIB PF02201.18 KPA41994.1 - 3.7e-20 71.6 0.1 7.2e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase PF00069.25 KPA41995.1 - 1.5e-68 231.0 0.0 2e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA41995.1 - 3.1e-35 121.7 0.0 3e-34 118.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA41995.1 - 8.4e-05 22.0 0.6 0.016 14.6 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KPA41995.1 - 0.0026 17.1 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KPA41995.1 - 0.0026 16.7 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KPA41995.1 - 0.0046 16.9 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KPA41995.1 - 0.14 11.8 0.3 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Uso1_p115_head PF04869.14 KPA41996.1 - 0.2 10.7 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region SNARE PF05739.19 KPA41998.1 - 2e-07 30.9 1.2 3.9e-07 30.0 1.2 1.5 1 0 0 1 1 1 1 SNARE domain FlgN PF05130.12 KPA41998.1 - 0.0051 17.3 2.1 0.09 13.3 0.1 2.4 2 0 0 2 2 2 1 FlgN protein DUF16 PF01519.16 KPA41998.1 - 0.022 15.3 0.3 4.6 7.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 FlxA PF14282.6 KPA41998.1 - 0.05 13.6 0.9 0.05 13.6 0.9 2.4 2 0 0 2 2 2 0 FlxA-like protein UPF0242 PF06785.11 KPA41998.1 - 0.8 9.8 6.5 5.2 7.1 0.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Glyco_hydro_18 PF00704.28 KPA41999.1 - 7.9e-82 275.5 2.0 1.4e-81 274.7 2.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ANAPC4_WD40 PF12894.7 KPA41999.1 - 0.00062 20.0 0.1 0.04 14.2 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPA41999.1 - 0.013 16.3 0.5 0.013 16.3 0.5 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat PPTA PF01239.22 KPA42000.1 - 2.5e-35 119.2 13.2 1.6e-07 30.8 0.9 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat JmjC PF02373.22 KPA42001.1 - 3.4e-09 37.1 0.1 9.2e-09 35.7 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KPA42001.1 - 9.2e-09 35.4 10.6 9.2e-09 35.4 10.6 2.7 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 UbiA PF01040.18 KPA42002.1 - 4.8e-41 140.7 18.3 6.3e-41 140.3 18.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.25 KPA42003.1 - 4.8e-51 171.2 0.7 6e-51 170.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 KPA42004.1 - 3.9e-21 74.6 0.3 9.7e-21 73.4 0.3 1.7 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) DUF2554 PF10829.8 KPA42005.1 - 0.15 12.5 0.2 3.3 8.2 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2554) HOOK PF05622.12 KPA42006.1 - 4.5e-22 78.0 72.5 9e-20 70.4 52.0 2.1 1 1 1 2 2 2 2 HOOK protein Alliinase_C PF04864.13 KPA42006.1 - 0.0023 16.9 0.2 0.0047 15.9 0.2 1.5 1 0 0 1 1 1 1 Allinase Synaptobrevin PF00957.21 KPA42006.1 - 6.7 6.6 9.6 0.5 10.2 2.1 3.1 2 0 0 2 2 2 0 Synaptobrevin ADK PF00406.22 KPA42007.1 - 1.9e-58 196.8 0.0 2.7e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KPA42007.1 - 4.3e-23 82.2 0.1 8.4e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KPA42007.1 - 3.3e-17 62.2 0.1 9.5e-17 60.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KPA42007.1 - 2.6e-05 24.8 0.0 4.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KPA42007.1 - 0.008 16.3 0.0 0.018 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Tmemb_cc2 PF10267.9 KPA42007.1 - 0.1 11.7 0.3 11 5.0 0.1 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Cytidylate_kin PF02224.18 KPA42007.1 - 0.15 11.7 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase MitMem_reg PF13012.6 KPA42008.1 - 4.3e-36 123.7 0.0 9.4e-36 122.6 0.0 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KPA42008.1 - 2.3e-31 108.2 0.3 6.6e-31 106.7 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 KPA42008.1 - 0.024 14.4 4.9 0.033 13.9 4.9 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Folliculin PF11704.8 KPA42008.1 - 0.084 12.7 1.1 0.13 12.2 1.1 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Connexin PF00029.19 KPA42008.1 - 0.25 11.1 3.3 0.39 10.4 3.3 1.3 1 0 0 1 1 1 0 Connexin Coprogen_oxidas PF01218.18 KPA42009.1 - 8.3e-145 481.0 0.1 9.8e-145 480.8 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF1651 PF07864.11 KPA42009.1 - 0.0049 17.2 0.0 0.029 14.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1651) Atrophin-1 PF03154.15 KPA42009.1 - 1.9 6.7 3.9 0.68 8.2 0.2 2.0 2 1 0 2 2 2 0 Atrophin-1 family Atg8 PF02991.16 KPA42010.1 - 2.7e-51 172.1 0.2 3.2e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KPA42010.1 - 3e-06 27.5 0.0 3.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Methyltransf_11 PF08241.12 KPA42011.1 - 7.8e-17 61.7 0.0 1.8e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KPA42011.1 - 2.8e-16 59.6 0.2 8.2e-14 51.5 0.0 2.3 3 0 0 3 3 3 2 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KPA42011.1 - 9.2e-16 58.1 0.0 1.3e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA42011.1 - 3.5e-15 56.5 0.2 3.2e-14 53.4 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA42011.1 - 2.9e-14 53.6 0.1 2e-13 50.9 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA42011.1 - 2.2e-12 47.0 0.1 4.5e-11 42.8 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA42011.1 - 2.9e-05 23.5 0.1 6.8e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KPA42011.1 - 0.00037 20.1 0.1 0.0025 17.4 0.1 2.1 1 1 0 2 2 2 1 Methionine biosynthesis protein MetW TPMT PF05724.11 KPA42011.1 - 0.0006 19.5 0.0 0.0012 18.6 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KPA42011.1 - 0.0014 18.2 0.1 0.0058 16.2 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_PK PF05891.12 KPA42011.1 - 0.0027 17.2 0.1 0.013 15.0 0.1 2.0 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PCMT PF01135.19 KPA42011.1 - 0.014 15.2 0.0 0.04 13.7 0.0 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KPA42011.1 - 0.022 14.1 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KPA42011.1 - 0.031 14.2 0.1 0.051 13.6 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.11 KPA42011.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Baculo_PEP_C PF04513.12 KPA42012.1 - 0.0052 16.8 1.1 3.5 7.6 0.2 2.9 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 KPA42012.1 - 0.068 12.5 1.2 31 3.8 0.4 3.3 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Trp_syntA PF00290.20 KPA42013.1 - 7.4e-96 320.0 0.0 1.4e-95 319.0 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KPA42013.1 - 1.1e-48 166.2 1.0 2.1e-48 165.3 1.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 KPA42013.1 - 0.1 12.4 0.1 4.4 7.1 0.1 2.5 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein STN PF07660.14 KPA42013.1 - 0.11 12.3 0.3 22 4.9 0.1 2.8 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain Ribosomal_L28 PF00830.19 KPA42014.1 - 1.6e-12 47.4 0.6 2.7e-12 46.7 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L28 family HAUS4 PF14735.6 KPA42015.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 4 Aminotran_1_2 PF00155.21 KPA42016.1 - 2e-97 326.6 0.0 2.3e-97 326.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sugar_tr PF00083.24 KPA42017.1 - 2.6e-82 277.1 16.3 3e-82 276.9 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA42017.1 - 1.4e-16 60.4 32.7 1.1e-09 37.7 3.2 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA42017.1 - 0.0038 16.1 10.9 0.011 14.6 6.7 2.6 2 1 1 3 3 3 1 MFS_1 like family Arylsulfotran_2 PF14269.6 KPA42018.1 - 1.2e-34 120.1 0.6 1.7e-23 83.5 0.2 2.1 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KPA42018.1 - 1.3e-08 34.2 0.0 4.5e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF730 PF05325.11 KPA42018.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF730) DUF5105 PF17118.5 KPA42018.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) ADH_zinc_N PF00107.26 KPA42019.1 - 4.9e-17 62.1 0.0 6.8e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPA42019.1 - 3.6e-06 26.6 0.5 8.1e-06 25.5 0.5 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KPA42019.1 - 0.00054 19.3 0.2 0.00076 18.8 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KPA42019.1 - 0.009 15.3 0.6 0.051 12.8 0.6 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 KPA42019.1 - 0.012 16.7 0.0 0.023 15.7 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KPA42019.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ELFV_dehydrog PF00208.21 KPA42019.1 - 0.084 12.6 0.3 0.13 12.0 0.3 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 KPA42019.1 - 0.1 13.1 0.1 0.15 12.5 0.1 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KPA42019.1 - 0.13 12.8 0.2 0.38 11.3 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPA42019.1 - 0.32 9.8 1.2 0.69 8.7 0.7 1.6 1 1 1 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KPA42019.1 - 0.32 10.0 3.2 0.73 8.9 1.8 1.8 1 1 1 2 2 2 0 FAD binding domain Peptidase_M28 PF04389.17 KPA42020.1 - 6.7e-42 143.4 0.0 8.8e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KPA42020.1 - 3e-13 49.6 0.1 7.2e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KPA42020.1 - 2.7e-06 27.2 0.0 7e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KPA42020.1 - 0.066 12.2 0.0 0.18 10.8 0.0 1.6 1 1 0 1 1 1 0 M42 glutamyl aminopeptidase E1-E2_ATPase PF00122.20 KPA42021.1 - 6.4e-34 117.0 20.1 1.8e-28 99.3 0.6 3.7 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KPA42021.1 - 3e-29 102.0 1.8 3e-29 102.0 1.8 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KPA42021.1 - 4.9e-20 71.4 0.0 1.2e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPA42021.1 - 2.4e-18 67.2 0.0 2.8e-14 53.9 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPA42021.1 - 1.5e-16 59.8 0.1 4.1e-16 58.4 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPA42021.1 - 1.9e-06 27.8 0.5 9e-05 22.3 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_cc PF11790.8 KPA42022.1 - 7.4e-68 228.7 0.2 8.6e-68 228.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fip1 PF05182.13 KPA42022.1 - 0.034 13.7 1.3 0.072 12.6 1.3 1.5 1 0 0 1 1 1 0 Fip1 motif Thiolase_N PF00108.23 KPA42023.1 - 6.3e-67 225.7 1.1 9.6e-67 225.1 1.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPA42023.1 - 3.4e-40 136.5 0.4 8.4e-40 135.2 0.4 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 KPA42023.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Sulfate_transp PF00916.20 KPA42024.1 - 2e-77 260.6 10.9 2e-77 260.6 10.9 1.3 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KPA42024.1 - 1.2e-15 57.1 0.0 2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KPA42024.1 - 0.00086 19.6 0.0 0.003 17.9 0.0 2.0 1 1 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KPA42024.1 - 0.018 15.5 2.6 0.018 15.5 2.6 2.9 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily DMT_6 PF04342.12 KPA42024.1 - 0.054 13.7 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Putative member of DMT superfamily (DUF486) Methyltransf_23 PF13489.6 KPA42025.1 - 2.8e-17 63.1 0.0 4.1e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA42025.1 - 1.5e-10 41.6 0.0 4.2e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA42025.1 - 1.6e-06 28.6 0.0 4.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA42025.1 - 2.9e-06 28.0 0.0 6.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA42025.1 - 6e-06 26.1 0.0 3.3e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA42025.1 - 0.0015 18.0 0.0 0.0071 15.7 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KPA42025.1 - 0.0053 16.2 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KPA42025.1 - 0.037 13.3 0.0 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain MTS PF05175.14 KPA42025.1 - 0.049 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SNF PF00209.18 KPA42026.1 - 4.5e-82 276.4 29.0 5.6e-81 272.8 28.8 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Peptidase_M15_3 PF08291.11 KPA42027.1 - 0.12 12.5 0.8 2.2 8.4 0.0 2.7 2 1 1 3 3 3 0 Peptidase M15 DUF3636 PF12331.8 KPA42028.1 - 6.7e-33 113.6 0.5 1.4e-32 112.6 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DUF812 PF05667.11 KPA42028.1 - 0.001 18.1 1.4 0.0016 17.4 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) UME PF08064.13 KPA42028.1 - 0.026 14.4 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 UME (NUC010) domain DUF4461 PF14688.6 KPA42028.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) DUF483 PF04467.12 KPA42028.1 - 0.16 11.9 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF483) CTP_transf_1 PF01148.20 KPA42029.1 - 4.7e-80 269.2 25.1 6e-80 268.8 25.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family HBD PF18534.1 KPA42029.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Helical bundle domain Amidase PF01425.21 KPA42030.1 - 1.3e-70 238.7 0.0 5.1e-70 236.7 0.0 1.8 1 1 0 1 1 1 1 Amidase 5_nucleotid_C PF02872.18 KPA42031.1 - 7.1e-32 110.8 0.0 1.2e-31 110.1 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KPA42031.1 - 1.4e-06 29.0 0.2 2.4e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glycos_transf_1 PF00534.20 KPA42033.1 - 2.5e-36 124.8 0.0 3.8e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KPA42033.1 - 2.7e-28 99.1 0.0 5.1e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KPA42033.1 - 9.7e-14 52.1 0.0 2e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KPA42033.1 - 1.6e-12 47.8 0.0 9.1e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KPA42033.1 - 6.4e-09 36.1 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 UDPG_MGDP_dh_N PF03721.14 KPA42034.1 - 2.4e-48 164.2 0.0 1.2e-30 106.5 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KPA42034.1 - 6.5e-33 112.8 0.0 1.4e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KPA42034.1 - 1.7e-23 83.0 0.0 6.1e-18 65.2 0.0 3.7 4 0 0 4 4 4 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 KPA42034.1 - 0.014 15.6 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KPA42034.1 - 0.02 15.1 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_75 PF07335.11 KPA42036.1 - 1.2e-64 217.5 0.6 1.8e-64 216.9 0.6 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 adh_short PF00106.25 KPA42037.1 - 1.7e-20 73.3 0.0 2.7e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA42037.1 - 1.1e-09 38.2 0.0 1.7e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA42037.1 - 0.0002 21.3 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF2254 PF10011.9 KPA42038.1 - 0.0084 15.0 0.1 0.0088 14.9 0.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) DUF4834 PF16118.5 KPA42038.1 - 0.033 15.1 0.0 0.041 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) WSS_VP PF12175.8 KPA42038.1 - 0.035 13.6 0.5 0.042 13.3 0.5 1.1 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP Cadherin_C_2 PF16492.5 KPA42038.1 - 0.045 14.5 0.0 0.05 14.3 0.0 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal MAP17 PF15807.5 KPA42038.1 - 0.29 11.4 1.5 0.5 10.6 1.5 1.4 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Red1 PF07964.11 KPA42040.1 - 0.028 12.7 0.6 0.033 12.5 0.6 1.0 1 0 0 1 1 1 0 Rec10 / Red1 NAD_binding_10 PF13460.6 KPA42041.1 - 5.1e-06 26.5 0.0 7.3e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KPA42041.1 - 9.4e-05 21.7 0.0 0.0075 15.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 KPA42041.1 - 0.00013 21.6 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA42041.1 - 0.0011 18.1 0.1 0.0016 17.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KPA42041.1 - 0.0046 16.1 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 KPA42041.1 - 0.015 15.4 0.1 0.03 14.4 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 KPA42041.1 - 0.044 13.3 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 KPA42041.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Con-6 PF10346.9 KPA42042.1 - 1.4e-17 63.4 3.1 2.7e-17 62.5 3.1 1.5 1 0 0 1 1 1 1 Conidiation protein 6 Podoplanin PF05808.11 KPA42043.1 - 0.051 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Podoplanin Yip1 PF04893.17 KPA42043.1 - 0.055 13.2 0.1 0.08 12.7 0.1 1.1 1 0 0 1 1 1 0 Yip1 domain DUF4381 PF14316.6 KPA42043.1 - 0.11 12.7 1.2 0.24 11.6 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Ni_hydr_CYTB PF01292.20 KPA42043.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 OAD_gamma PF04277.13 KPA42043.1 - 0.18 12.4 1.2 5.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CENP-L PF13092.6 KPA42044.1 - 1e-51 175.4 0.0 7.8e-50 169.3 0.0 2.1 2 0 0 2 2 2 2 Kinetochore complex Sim4 subunit Fta1 Moricin PF06451.11 KPA42044.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Moricin Asparaginase_II PF06089.12 KPA42045.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 L-asparaginase II Aldo_ket_red PF00248.21 KPA42046.1 - 1.1e-36 126.5 0.0 5.2e-36 124.3 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family TIP49_C PF17856.1 KPA42046.1 - 0.018 15.2 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 TIP49 AAA-lid domain NAD_binding_7 PF13241.6 KPA42047.1 - 3.6e-30 104.5 0.0 5e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KPA42047.1 - 2.1e-26 91.3 0.0 3.2e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KPA42047.1 - 4.1e-14 51.7 0.1 6.6e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KPA42047.1 - 0.0011 18.3 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Cytotoxic PF09000.10 KPA42047.1 - 0.037 14.4 0.0 0.55 10.6 0.0 2.2 2 0 0 2 2 2 0 Cytotoxic TrkA_N PF02254.18 KPA42047.1 - 0.15 12.3 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain FYVE PF01363.21 KPA42048.1 - 1.5e-23 82.7 19.6 5.6e-17 61.6 5.7 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KPA42048.1 - 3.7e-18 65.0 0.3 1.1e-17 63.5 0.3 1.9 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 KPA42048.1 - 0.00077 19.6 2.2 0.00077 19.6 2.2 4.0 3 1 1 4 4 4 1 AN1-like Zinc finger TMF_TATA_bd PF12325.8 KPA42048.1 - 0.015 15.5 2.1 0.015 15.5 2.1 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding PhnA_Zn_Ribbon PF08274.12 KPA42048.1 - 0.026 14.5 0.0 21 5.2 0.0 4.1 4 1 0 4 4 4 0 PhnA Zinc-Ribbon ABC_tran_CTD PF16326.5 KPA42048.1 - 0.04 14.2 3.9 4 7.7 0.2 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain zf-Di19 PF05605.12 KPA42048.1 - 0.042 14.1 0.1 0.042 14.1 0.1 3.0 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding bZIP_1 PF00170.21 KPA42048.1 - 0.063 13.4 3.3 0.75 9.9 0.0 3.3 3 0 0 3 3 3 0 bZIP transcription factor Chorismate_bind PF00425.18 KPA42048.1 - 0.11 12.1 0.6 0.24 10.9 0.6 1.5 1 0 0 1 1 1 0 chorismate binding enzyme DUF16 PF01519.16 KPA42048.1 - 0.18 12.3 2.0 28 5.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function DUF16 zf-C2H2_2 PF12756.7 KPA42048.1 - 0.21 12.0 5.3 0.78 10.1 0.0 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Seryl_tRNA_N PF02403.22 KPA42048.1 - 0.32 11.2 2.6 0.35 11.1 0.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-C2H2_4 PF13894.6 KPA42048.1 - 1.3 10.1 0.0 1.3 10.1 0.0 5.9 5 1 1 6 6 5 0 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 KPA42048.1 - 1.7 9.0 6.9 5.3 7.4 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon Csm1_N PF18504.1 KPA42048.1 - 2 8.8 5.7 8.7 6.8 0.1 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain zf-C2H2_9 PF16293.5 KPA42048.1 - 5.5 6.9 6.7 11 5.9 0.0 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Ank_4 PF13637.6 KPA42049.1 - 8.2e-14 51.8 1.5 3.5e-08 33.8 0.2 4.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA42049.1 - 2.4e-11 42.8 0.7 0.00058 20.1 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 KPA42049.1 - 6.4e-11 42.7 0.2 0.00089 19.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KPA42049.1 - 4.9e-10 39.4 6.2 0.0019 18.6 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KPA42049.1 - 1.6e-05 25.1 0.9 0.079 13.3 0.2 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KPA42049.1 - 9.8e-05 22.2 0.9 0.00067 19.5 0.4 2.5 2 1 0 2 2 2 1 KilA-N domain BLOC1_2 PF10046.9 KPA42049.1 - 0.14 12.4 1.1 9.6 6.6 1.2 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.14 KPA42049.1 - 0.19 12.1 4.3 0.26 11.6 2.9 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Filament PF00038.21 KPA42049.1 - 0.55 9.8 7.7 0.22 11.1 5.2 1.6 2 0 0 2 2 2 0 Intermediate filament protein Muted PF14942.6 KPA42049.1 - 2.5 8.4 6.9 2.8 8.3 4.7 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Exonuc_VII_L PF02601.15 KPA42049.1 - 4.3 6.8 10.5 0.58 9.7 5.5 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Complex1_LYR PF05347.15 KPA42050.1 - 1.6e-06 28.0 0.6 4.6e-06 26.6 0.6 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KPA42050.1 - 0.001 19.8 2.8 0.0026 18.5 2.8 2.0 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KPA42050.1 - 0.11 13.1 0.3 0.28 11.8 0.3 1.7 1 0 0 1 1 1 0 Complex1_LYR-like Acetyltransf_1 PF00583.25 KPA42051.1 - 1e-16 61.2 0.0 2.3e-16 60.1 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA42051.1 - 1.3e-07 31.9 0.0 2.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA42051.1 - 2.9e-07 30.3 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KPA42051.1 - 5.4e-06 26.4 0.0 8.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KPA42051.1 - 0.0039 17.9 0.0 0.0044 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KPA42051.1 - 0.042 14.0 0.0 0.061 13.5 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA42051.1 - 0.13 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MFS_1 PF07690.16 KPA42052.1 - 1e-36 126.6 28.3 1.6e-35 122.7 28.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily HRG PF16954.5 KPA42052.1 - 0.25 11.8 7.5 1.4 9.4 0.5 3.8 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF1129 PF06570.11 KPA42052.1 - 0.93 8.9 9.4 0.83 9.1 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4234 PF14018.6 KPA42052.1 - 3.1 8.0 9.2 0.18 12.0 0.3 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4234) Methyltransf_31 PF13847.6 KPA42053.1 - 2.7e-24 85.7 0.0 4.2e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA42053.1 - 1.1e-23 83.7 0.0 1.9e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA42053.1 - 2.4e-22 79.5 0.0 7.7e-22 77.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA42053.1 - 1e-16 61.0 0.0 1.5e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KPA42053.1 - 1.1e-15 58.1 0.0 2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA42053.1 - 1.2e-14 54.5 0.0 6e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KPA42053.1 - 4.4e-08 32.9 0.0 6.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 KPA42053.1 - 1.5e-06 27.9 0.0 0.042 13.3 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 KPA42053.1 - 4.2e-05 23.0 0.0 5.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 KPA42053.1 - 6.4e-05 22.2 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase DUF938 PF06080.12 KPA42053.1 - 7e-05 22.7 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 KPA42053.1 - 0.00011 21.8 0.0 0.00065 19.2 0.0 2.2 2 1 1 3 3 3 1 Putative methyltransferase PCMT PF01135.19 KPA42053.1 - 0.00038 20.3 0.0 0.00057 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KPA42053.1 - 0.00045 20.2 0.0 0.00069 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KPA42053.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.9 KPA42053.1 - 0.0039 17.0 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase GCD14 PF08704.10 KPA42053.1 - 0.004 16.9 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 KPA42053.1 - 0.005 16.3 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KPA42053.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 KPA42053.1 - 0.034 12.7 0.0 0.059 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 KPA42053.1 - 0.035 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.11 KPA42053.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MFS_1 PF07690.16 KPA42054.1 - 2.3e-14 53.1 54.2 2.3e-07 30.1 28.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KPA42054.1 - 0.00027 20.4 19.6 0.00043 19.7 19.6 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ADH_N PF08240.12 KPA42055.1 - 1.2e-28 99.1 0.2 2.5e-28 98.1 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA42055.1 - 3.8e-08 33.4 0.2 9.3e-08 32.1 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KPA42055.1 - 4.2e-07 29.8 0.2 9.9e-07 28.6 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 KPA42055.1 - 0.00017 21.2 0.0 0.006 16.1 0.0 2.2 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 KPA42055.1 - 0.0013 17.6 0.5 0.0061 15.3 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KPA42055.1 - 0.0026 17.1 0.2 0.0045 16.3 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KPA42055.1 - 0.06 12.6 0.1 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 KPA42055.1 - 0.064 12.3 0.4 0.096 11.7 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KPA42055.1 - 0.074 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA42055.1 - 0.092 13.3 0.3 0.48 11.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPA42055.1 - 0.34 10.2 1.2 0.42 9.9 0.6 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase AltA1 PF16541.5 KPA42056.1 - 4.7e-16 59.6 6.0 7.1e-16 59.0 6.0 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 GST_C_2 PF13410.6 KPA42057.1 - 8.9e-09 35.3 0.1 1.3e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA42057.1 - 2.1e-05 24.6 0.0 4.8e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA42057.1 - 0.0038 17.4 0.0 0.0066 16.6 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KPA42057.1 - 0.072 13.7 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Amidase PF01425.21 KPA42058.1 - 2e-67 228.1 0.0 2.3e-66 224.7 0.0 2.0 1 1 0 1 1 1 1 Amidase Acetyltransf_1 PF00583.25 KPA42059.1 - 8.8e-16 58.2 0.0 5.8e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA42059.1 - 1.5e-14 54.1 0.0 5.1e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA42059.1 - 2e-10 40.7 0.0 2.8e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA42059.1 - 1.3e-08 34.9 0.2 5.3e-05 23.3 0.1 3.5 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA42059.1 - 2.7e-08 33.6 0.1 0.00017 21.5 0.0 2.7 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_CG PF14542.6 KPA42059.1 - 9.5e-05 22.5 0.0 0.0088 16.2 0.0 2.3 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase G_glu_transpept PF01019.21 KPA42060.1 - 1.1e-165 552.3 0.3 1.3e-165 552.1 0.3 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Kelch_1 PF01344.25 KPA42061.1 - 8.4e-28 95.7 12.1 2e-09 36.9 0.0 6.8 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.6 KPA42061.1 - 1.2e-24 85.7 13.8 1.8e-06 28.0 0.0 7.1 4 2 4 8 8 8 4 Kelch motif Kelch_4 PF13418.6 KPA42061.1 - 4.4e-19 68.2 17.2 0.00012 22.0 0.0 7.4 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KPA42061.1 - 5.4e-16 57.9 9.1 9.9e-06 25.3 0.0 6.1 6 2 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KPA42061.1 - 1e-13 50.9 0.4 0.039 14.0 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KPA42061.1 - 1.1e-13 51.0 10.7 0.0026 18.0 0.1 6.2 7 0 0 7 7 7 4 Galactose oxidase, central domain CDO_I PF05995.12 KPA42061.1 - 0.042 13.2 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Cysteine dioxygenase type I Beta-lactamase PF00144.24 KPA42062.1 - 5.3e-31 108.1 0.0 8.9e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase HNH_2 PF13391.6 KPA42063.1 - 0.00023 21.3 0.1 0.00058 19.9 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease DAO PF01266.24 KPA42064.1 - 5.8e-40 137.9 0.1 6.8e-40 137.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA42064.1 - 5.3e-05 23.4 0.6 0.00018 21.6 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPA42064.1 - 0.00017 20.9 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KPA42064.1 - 0.00065 18.9 1.1 0.0027 16.8 1.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA42064.1 - 0.0069 15.6 0.4 0.084 12.1 0.4 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA42064.1 - 0.0076 15.5 0.0 0.096 11.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA42064.1 - 0.015 15.3 0.3 0.097 12.7 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KPA42064.1 - 0.017 13.9 0.0 0.97 8.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KPA42064.1 - 0.1 11.6 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Zn_clus PF00172.18 KPA42065.1 - 6.6e-05 22.9 11.3 0.00012 22.1 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA42065.1 - 0.0021 17.2 0.6 0.0049 15.9 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C69 PF03577.15 KPA42066.1 - 5.7e-22 78.2 0.0 1.2e-21 77.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase family C69 Pkinase PF00069.25 KPA42067.1 - 7.2e-19 68.2 0.0 1.9e-18 66.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA42067.1 - 2.1e-16 60.0 0.0 2.8e-15 56.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KPA42067.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_L17 PF01196.19 KPA42067.1 - 0.16 12.9 0.1 2.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L17 CorA PF01544.18 KPA42068.1 - 4.5e-08 32.8 2.2 8.1e-08 31.9 2.2 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein AA_permease PF00324.21 KPA42070.1 - 1.2e-53 182.4 35.5 8.2e-52 176.4 35.5 2.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA42070.1 - 9.2e-28 97.2 31.5 1.6e-27 96.5 31.1 1.6 1 1 0 1 1 1 1 Amino acid permease Sprouty PF05210.13 KPA42070.1 - 2.3 8.6 8.1 0.16 12.4 0.4 2.7 4 0 0 4 4 4 0 Sprouty protein (Spry) CorA PF01544.18 KPA42071.1 - 5.4e-09 35.8 0.1 9.5e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 KPA42071.1 - 0.12 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SARS_lipid_bind PF09399.10 KPA42072.1 - 0.0048 17.0 0.0 0.0056 16.8 0.0 1.1 1 0 0 1 1 1 1 SARS lipid binding protein Mito_carr PF00153.27 KPA42073.1 - 5.5e-41 138.4 5.7 7.2e-17 61.1 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S8 PF00082.22 KPA42074.1 - 2.3e-38 132.2 0.8 3.2e-38 131.7 0.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KPA42074.1 - 4.1e-27 94.0 0.4 8.5e-27 93.0 0.4 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KPA42074.1 - 0.0035 18.1 0.0 0.01 16.6 0.0 1.8 1 0 0 1 1 1 1 Peptidase S8 pro-domain PX PF00787.24 KPA42075.1 - 6.6e-21 74.4 0.4 6.6e-21 74.4 0.4 1.8 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KPA42075.1 - 4.5e-07 29.7 10.6 0.002 17.7 10.6 2.3 1 1 0 1 1 1 1 Vps5 C terminal like BAR PF03114.18 KPA42075.1 - 0.0019 17.9 10.5 0.032 13.9 10.5 2.2 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KPA42075.1 - 0.029 14.1 3.3 0.1 12.3 0.2 2.4 2 1 0 2 2 2 0 BAR domain of APPL family DUF3140 PF11338.8 KPA42075.1 - 0.31 11.5 0.1 0.31 11.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) LETM1 PF07766.13 KPA42076.1 - 8.5e-104 346.6 0.8 1.5e-103 345.8 0.8 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 KPA42076.1 - 8.8e-05 22.2 0.0 0.0052 16.5 0.0 2.5 2 0 0 2 2 2 1 SAP domain Glyco_hydro_3 PF00933.21 KPA42077.1 - 1.7e-48 165.6 0.0 2.5e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KPA42077.1 - 7.4e-06 26.0 0.2 0.00019 21.5 0.0 2.2 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain ADK PF00406.22 KPA42080.1 - 2.5e-35 121.8 0.0 1.2e-18 67.6 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 KPA42080.1 - 2.7e-16 59.3 0.0 4.4e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KPA42080.1 - 1.8e-13 51.1 0.0 7.3e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KPA42080.1 - 0.00061 20.3 0.0 0.0091 16.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KPA42080.1 - 0.035 14.3 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ER_lumen_recept PF00810.18 KPA42081.1 - 6.9e-42 143.7 10.5 1e-41 143.2 10.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KPA42081.1 - 0.077 12.8 0.0 0.077 12.8 0.0 2.9 3 0 0 3 3 3 0 PQ loop repeat LicD PF04991.13 KPA42082.1 - 2.6e-17 63.7 10.8 3.9e-10 40.3 4.9 2.3 1 1 1 2 2 2 2 LicD family PAS_11 PF14598.6 KPA42083.1 - 0.086 13.0 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 PAS domain CS PF04969.16 KPA42084.1 - 1.1e-16 61.6 0.4 2.4e-16 60.5 0.1 1.7 2 0 0 2 2 2 1 CS domain PduV-EutP PF10662.9 KPA42084.1 - 0.025 14.3 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MAT1 PF06391.13 KPA42085.1 - 6.1e-32 111.1 12.9 8.5e-32 110.6 12.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KPA42085.1 - 6.8e-31 105.9 9.7 1e-30 105.3 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPA42085.1 - 0.00022 21.0 6.9 0.00041 20.2 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA42085.1 - 0.00043 20.1 7.3 0.0016 18.2 7.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MRP-S26 PF14943.6 KPA42085.1 - 0.0029 17.5 15.1 0.0047 16.8 15.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 zf-RING_2 PF13639.6 KPA42085.1 - 0.0033 17.7 6.8 0.0063 16.8 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPA42085.1 - 0.024 14.5 7.7 0.082 12.8 7.8 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3797 PF12677.7 KPA42085.1 - 0.029 14.3 3.2 0.062 13.2 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_10 PF16685.5 KPA42085.1 - 0.11 12.7 2.6 0.24 11.6 2.6 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KPA42085.1 - 0.19 11.5 11.8 1.6 8.6 12.0 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KPA42085.1 - 0.32 11.1 6.5 0.64 10.1 6.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KPA42085.1 - 1.8 8.6 11.4 29 4.7 11.8 2.2 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KPA42085.1 - 6.9 6.6 8.6 65 3.5 0.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 ANTH PF07651.16 KPA42086.1 - 1.1e-68 231.3 1.2 1.4e-68 230.9 1.2 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KPA42086.1 - 1.7e-08 34.5 0.0 2.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 KPA42086.1 - 0.019 15.3 41.0 0.019 15.3 41.0 5.1 1 1 3 4 4 4 0 Domain of unknown function (DUF1720) adh_short PF00106.25 KPA42088.1 - 2.7e-43 147.7 0.2 3.9e-43 147.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA42088.1 - 4.6e-40 137.6 0.5 1.8e-39 135.7 0.5 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA42088.1 - 8.5e-09 35.6 0.4 1.3e-08 34.9 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA42088.1 - 1.3e-05 24.8 0.0 2.9e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA42088.1 - 0.00043 19.8 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KPA42088.1 - 0.0076 16.2 0.2 0.031 14.2 0.2 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KPA42088.1 - 0.008 15.3 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KPA42088.1 - 0.02 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KPA42088.1 - 0.025 15.1 0.0 0.052 14.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KPA42088.1 - 0.03 13.7 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 KPA42088.1 - 0.04 13.5 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family ApbA PF02558.16 KPA42088.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KPA42088.1 - 0.12 12.3 0.0 0.96 9.3 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RhoGAP PF00620.27 KPA42089.1 - 0.0048 16.7 0.1 0.0086 15.9 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain Sugar_tr PF00083.24 KPA42090.1 - 1.2e-93 314.5 24.7 1.3e-93 314.3 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA42090.1 - 7.9e-23 80.9 59.4 1.8e-21 76.5 31.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sarcolipin PF05366.11 KPA42090.1 - 0.16 11.7 2.4 0.53 10.0 2.4 1.9 1 0 0 1 1 1 0 Sarcolipin Zn_clus PF00172.18 KPA42091.1 - 2.1e-08 34.2 10.6 5.2e-08 32.9 10.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA42092.1 - 2.5e-15 56.2 0.0 4.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA42092.1 - 3e-09 36.9 10.4 6e-09 35.9 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.28 KPA42093.1 - 6.8e-20 71.4 0.2 7.7e-20 71.3 0.2 1.0 1 0 0 1 1 1 1 NUDIX domain UPF0193 PF05250.11 KPA42093.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) Atg14 PF10186.9 KPA42094.1 - 2.8e-13 49.7 1.9 7.2e-13 48.3 1.9 1.6 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KPA42094.1 - 6.9e-12 45.0 0.1 7.7e-08 31.6 0.0 3.4 2 1 0 2 2 2 2 Vacuolar protein sorting 38 UPF0242 PF06785.11 KPA42094.1 - 0.011 15.9 3.9 0.029 14.5 3.9 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COesterase PF00135.28 KPA42095.1 - 1.7e-90 304.4 0.0 2e-90 304.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA42095.1 - 0.00066 19.6 0.2 0.011 15.6 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA42095.1 - 0.016 14.7 0.4 0.029 13.8 0.4 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family ketoacyl-synt PF00109.26 KPA42096.1 - 1.6e-79 267.1 0.0 3.7e-79 265.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KPA42096.1 - 1.4e-70 237.8 0.1 4e-70 236.3 0.1 1.9 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KPA42096.1 - 3.1e-36 125.5 0.0 5e-35 121.5 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KPA42096.1 - 8.3e-33 112.9 0.9 1.8e-32 111.8 0.9 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KPA42096.1 - 1.3e-22 79.9 8.2 5.8e-11 42.6 1.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 KPA42096.1 - 4.5e-22 78.5 0.0 7.9e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PS-DH PF14765.6 KPA42096.1 - 2.9e-13 49.7 0.1 5.8e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KPA42096.1 - 2.3e-06 28.0 0.0 7e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KPA42096.1 - 6.1e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 KPA42096.1 - 0.0013 18.2 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.10 KPA42096.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 KPA42096.1 - 0.025 14.0 0.0 0.059 12.8 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 KPA42096.1 - 0.062 13.4 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_2 PF00891.18 KPA42097.1 - 8e-29 100.4 0.0 1.4e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KPA42097.1 - 0.011 16.5 0.0 0.023 15.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KPA42097.1 - 0.019 15.7 0.0 0.047 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KPA42097.1 - 0.041 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.19 KPA42098.1 - 2e-15 56.9 0.0 4.1e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA42098.1 - 2.3e-06 27.4 0.6 0.014 15.0 0.0 2.5 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA42098.1 - 1.1e-05 24.8 0.0 0.059 12.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPA42098.1 - 0.00079 18.6 0.0 0.0018 17.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KPA42098.1 - 0.0029 17.0 0.1 0.0078 15.6 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA42098.1 - 0.0037 17.4 0.0 0.016 15.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPA42098.1 - 0.0062 15.3 0.0 0.31 9.7 0.0 2.4 2 0 0 2 2 2 1 HI0933-like protein NMT1 PF09084.11 KPA42099.1 - 0.001 19.1 0.0 0.0021 18.0 0.0 1.6 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 KPA42099.1 - 0.0011 18.4 0.0 0.012 15.0 0.0 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NAPRTase_N PF17767.1 KPA42099.1 - 0.0068 16.8 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF4522 PF15022.6 KPA42100.1 - 0.035 14.4 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) EamA PF00892.20 KPA42101.1 - 4.7e-13 49.5 31.4 3.3e-07 30.5 3.3 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 KPA42101.1 - 2.9e-10 39.8 1.4 2.9e-10 39.8 1.4 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 KPA42101.1 - 7.9e-07 28.6 3.0 7.9e-07 28.6 3.0 2.3 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport UAA PF08449.11 KPA42101.1 - 3.9e-06 26.3 10.9 6.6e-06 25.5 10.9 1.3 1 0 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 KPA42101.1 - 1.4e-05 24.7 12.2 1.4e-05 24.7 12.2 1.7 2 0 0 2 2 2 1 Solute carrier family 35 CRT-like PF08627.10 KPA42101.1 - 0.002 17.1 9.1 0.0068 15.4 1.5 2.4 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Heme_oxygenase PF01126.20 KPA42102.1 - 5.5e-09 36.1 0.0 4.9e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Heme oxygenase WD40 PF00400.32 KPA42103.1 - 1.8e-09 38.0 9.9 0.002 18.9 0.4 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat GATase_4 PF13230.6 KPA42104.1 - 2.3e-15 56.2 0.0 8.7e-13 47.8 0.0 2.1 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 KPA42104.1 - 5.3e-09 36.4 0.0 9.8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Defensin_like PF10868.8 KPA42105.1 - 2.9 8.7 9.0 0.23 12.2 1.1 2.3 2 0 0 2 2 2 0 Cysteine-rich antifungal protein 2, defensin-like Fungal_trans_2 PF11951.8 KPA42106.1 - 3.9e-50 170.8 5.7 1.7e-49 168.7 5.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA42106.1 - 1.4e-07 31.5 7.4 3.3e-07 30.3 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.23 KPA42107.1 - 1.2e-61 208.5 0.0 1.7e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPA42107.1 - 6.8e-10 39.1 0.0 1.4e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Zap1_zf2 PF18217.1 KPA42107.1 - 0.009 16.0 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 1 Zap1 zinc finger 2 GSHPx PF00255.19 KPA42108.1 - 1e-39 134.5 0.0 1.2e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KPA42108.1 - 0.0049 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPA42108.1 - 0.059 13.1 0.0 0.065 12.9 0.0 1.4 1 1 0 1 1 1 0 Redoxin DUF4174 PF13778.6 KPA42108.1 - 0.26 11.8 0.0 0.48 10.9 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) DAO PF01266.24 KPA42109.1 - 7.5e-71 239.5 0.3 9.1e-71 239.3 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA42109.1 - 5.9e-07 29.0 1.7 0.00086 18.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA42109.1 - 4.8e-06 27.0 0.5 0.069 13.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA42109.1 - 0.00016 21.9 0.1 0.00036 20.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 KPA42109.1 - 0.0011 18.4 0.6 0.13 11.7 0.1 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Mqo PF06039.15 KPA42109.1 - 0.0016 17.1 0.2 0.18 10.4 0.1 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Trp_halogenase PF04820.14 KPA42109.1 - 0.0075 15.2 0.2 0.01 14.7 0.2 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.19 KPA42109.1 - 0.025 13.8 0.0 0.48 9.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Amino_oxidase PF01593.24 KPA42109.1 - 0.029 13.6 0.6 0.053 12.8 0.2 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Prenylcys_lyase PF07156.14 KPA42109.1 - 0.036 13.2 0.1 0.055 12.6 0.1 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase Sacchrp_dh_NADP PF03435.18 KPA42109.1 - 0.059 13.6 0.5 0.18 12.1 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain MHB PF16525.5 KPA42109.1 - 0.067 13.4 0.0 0.89 9.8 0.0 2.5 3 0 0 3 3 2 0 Haemophore, haem-binding Thi4 PF01946.17 KPA42109.1 - 0.068 12.4 0.3 0.068 12.4 0.3 1.5 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KPA42109.1 - 0.16 12.0 1.1 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Spidroin_N PF16763.5 KPA42109.1 - 0.19 11.7 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term MBF1 PF08523.10 KPA42109.1 - 0.42 11.1 3.6 0.64 10.5 0.3 2.2 2 0 0 2 2 2 0 Multiprotein bridging factor 1 PH PF00169.29 KPA42110.1 - 0.0052 17.3 0.1 0.02 15.4 0.0 2.0 2 0 0 2 2 2 1 PH domain COX14 PF14880.6 KPA42111.1 - 0.083 12.7 0.3 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Spem1 PF15670.5 KPA42111.1 - 0.13 11.8 7.8 0.2 11.2 7.8 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 HSP70 PF00012.20 KPA42112.1 - 5.1e-266 883.6 13.4 5.8e-266 883.4 13.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KPA42112.1 - 3.9e-13 48.9 4.1 3.1e-11 42.7 1.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KPA42112.1 - 0.00096 18.9 0.1 0.0033 17.2 0.1 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 KPA42112.1 - 0.045 13.0 1.2 0.63 9.2 0.0 2.6 2 1 1 3 3 3 0 StbA protein Ploopntkinase3 PF18751.1 KPA42112.1 - 0.069 13.1 0.2 6.4 6.6 0.0 2.6 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 Big_3_4 PF13754.6 KPA42112.1 - 0.12 12.1 0.0 7.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function BPD_transp_1 PF00528.22 KPA42113.1 - 0.014 15.2 0.1 0.018 14.8 0.1 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component Ctr PF04145.15 KPA42113.1 - 0.044 14.4 0.0 0.047 14.3 0.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Spore_III_AF PF09581.10 KPA42113.1 - 0.19 11.7 0.0 2 8.4 0.1 1.9 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) SRP68 PF16969.5 KPA42114.1 - 6e-200 666.0 5.1 6.8e-200 665.8 5.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PT-TG PF14449.6 KPA42114.1 - 0.02 14.8 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Pre-toxin TG SNF2_N PF00176.23 KPA42115.1 - 2e-72 243.8 0.0 3.3e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA42115.1 - 3.3e-13 49.9 0.0 8.7e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KPA42115.1 - 1.3e-06 28.3 4.0 2.2e-06 27.5 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 KPA42115.1 - 0.00062 19.6 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.6 KPA42115.1 - 0.0016 18.2 1.3 0.0016 18.2 1.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KPA42115.1 - 0.003 17.6 0.0 0.013 15.5 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KPA42115.1 - 0.0097 15.8 5.7 0.039 13.8 5.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPA42115.1 - 0.017 15.0 5.4 0.053 13.4 5.4 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KPA42115.1 - 0.032 14.6 2.9 0.07 13.5 2.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KPA42115.1 - 0.1 12.7 3.5 0.08 13.0 1.6 1.9 1 1 0 1 1 1 0 RING-type zinc-finger MPDZ_u10 PF16667.5 KPA42115.1 - 1.4 9.9 5.0 5.1 8.1 5.0 2.0 1 0 0 1 1 1 0 Unstructured region 10 on multiple PDZ protein zf-C3HC4_4 PF15227.6 KPA42115.1 - 1.7 8.9 4.1 26 5.1 4.6 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING GCP_N_terminal PF17681.1 KPA42116.1 - 1.7e-64 218.4 0.0 3.5e-64 217.4 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KPA42116.1 - 1.2e-61 208.9 3.6 1.2e-61 208.9 3.6 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Proteasome PF00227.26 KPA42117.1 - 3.8e-56 189.6 0.1 5e-56 189.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KPA42117.1 - 1.7e-12 46.8 0.0 3.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Fungal_trans_2 PF11951.8 KPA42118.1 - 9.6e-20 70.7 3.9 2.1e-13 49.9 0.2 2.9 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA42118.1 - 5.1e-08 32.9 11.2 9.7e-08 32.0 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA42118.1 - 0.0024 17.0 1.7 0.081 11.9 0.0 2.4 3 0 0 3 3 3 2 Fungal specific transcription factor domain Methyltransf_8 PF05148.15 KPA42119.1 - 8.1e-60 202.4 0.0 1.2e-57 195.3 0.0 2.7 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KPA42119.1 - 3e-06 27.8 0.0 1.7e-05 25.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA42119.1 - 0.00012 22.7 0.0 0.04 14.6 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KPA42119.1 - 0.033 14.2 0.0 0.033 14.2 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KPA42119.1 - 0.079 12.5 0.0 4 6.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KPA42119.1 - 0.15 11.9 2.9 9.4 6.0 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain Raftlin PF15250.6 KPA42119.1 - 1.4 7.6 10.6 2 7.1 10.6 1.2 1 0 0 1 1 1 0 Raftlin Zip PF02535.22 KPA42119.1 - 6.1 6.0 9.5 60 2.7 10.1 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Presenilin PF01080.17 KPA42119.1 - 8.1 5.1 15.9 16 4.2 15.9 1.5 1 0 0 1 1 1 0 Presenilin Asp_protease PF09668.10 KPA42120.1 - 4.6e-62 207.3 0.1 6.8e-62 206.8 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KPA42120.1 - 5.3e-25 87.8 0.0 1.5e-24 86.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KPA42120.1 - 1.6e-12 47.9 0.1 4e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.31 KPA42120.1 - 4.7e-10 39.2 0.0 1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 KPA42120.1 - 9.7e-10 38.1 0.0 2.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.11 KPA42120.1 - 1.7e-05 24.6 0.0 3.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KPA42120.1 - 0.00054 20.2 0.0 0.0015 18.8 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 KPA42120.1 - 0.0041 16.9 0.1 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 KPA42120.1 - 0.0083 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UN_NPL4 PF11543.8 KPA42120.1 - 0.014 15.9 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF4813 PF16072.5 KPA42120.1 - 0.48 10.0 22.6 0.78 9.3 22.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Acetyltransf_10 PF13673.7 KPA42121.1 - 9.7e-07 28.8 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA42121.1 - 4.9e-06 26.8 0.0 8.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA42121.1 - 0.0046 17.3 0.0 0.0075 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA42121.1 - 0.17 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pribosyltran PF00156.27 KPA42122.1 - 4.3e-16 58.8 0.5 6.3e-16 58.3 0.5 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NOG1_N PF17835.1 KPA42123.1 - 1.1e-48 165.2 0.1 1.1e-48 165.2 0.1 2.1 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KPA42123.1 - 1.3e-27 95.5 3.4 3.6e-27 94.1 3.4 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KPA42123.1 - 1.9e-25 88.4 0.3 4.1e-25 87.3 0.3 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KPA42123.1 - 2.7e-15 56.4 0.0 6.2e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPA42123.1 - 2.5e-07 30.4 0.0 6.2e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KPA42123.1 - 0.0063 16.4 1.6 2.1 8.2 0.0 3.5 4 1 0 4 4 4 1 RsgA GTPase AAA_16 PF13191.6 KPA42123.1 - 0.0068 16.8 0.2 0.67 10.3 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain Dynamin_N PF00350.23 KPA42123.1 - 0.0077 16.3 0.0 3.6 7.6 0.0 2.8 1 1 1 2 2 2 2 Dynamin family AAA_23 PF13476.6 KPA42123.1 - 0.059 13.9 1.3 17 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KPA42123.1 - 0.1 12.8 0.6 1.1 9.5 0.0 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTP_transf_6 PF06042.11 KPA42123.1 - 0.15 11.9 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 Nucleotidyltransferase GDI PF00996.18 KPA42124.1 - 1.7e-195 649.6 0.0 2e-195 649.4 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox PF00070.27 KPA42124.1 - 0.03 14.9 0.1 0.55 10.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA42124.1 - 0.04 14.2 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.13 KPA42125.1 - 3e-22 78.5 0.3 5.5e-22 77.7 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 KPA42125.1 - 0.053 13.0 1.0 0.083 12.3 1.0 1.2 1 0 0 1 1 1 0 Clc-like zf-H2C2_2 PF13465.6 KPA42126.1 - 3.3e-06 27.3 10.9 7e-06 26.2 1.1 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KPA42126.1 - 0.00024 21.3 4.1 0.00042 20.6 4.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KPA42126.1 - 0.00027 21.5 15.1 0.024 15.5 5.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA42126.1 - 0.027 14.8 3.1 3.4 8.0 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KPA42126.1 - 0.07 13.6 14.6 0.14 12.6 7.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Fungal_trans PF04082.18 KPA42127.1 - 1.2e-20 73.6 0.1 1.9e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_9 PF01075.17 KPA42127.1 - 0.085 12.2 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) HD PF01966.22 KPA42130.1 - 7.2e-08 32.7 0.2 2.8e-07 30.8 0.1 1.9 2 0 0 2 2 2 1 HD domain F-box-like PF12937.7 KPA42131.1 - 4.4e-05 23.3 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA42131.1 - 0.00088 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain zf-U1 PF06220.12 KPA42134.1 - 6.4e-22 77.0 3.4 9.4e-22 76.5 3.4 1.3 1 0 0 1 1 1 1 U1 zinc finger EMP24_GP25L PF01105.24 KPA42135.1 - 7.1e-41 140.2 0.0 8.2e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sec34 PF04136.15 KPA42135.1 - 0.029 14.2 0.1 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 Sec34-like family tRNA-synt_1b PF00579.25 KPA42136.1 - 9.9e-24 84.2 0.0 1.8e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Sdh5 PF03937.16 KPA42137.1 - 5.4e-24 83.9 0.1 2.3e-23 82.0 0.1 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase MIS13 PF08202.11 KPA42138.1 - 5.1e-58 196.7 0.0 1.1e-57 195.7 0.0 1.5 1 0 0 1 1 1 1 Mis12-Mtw1 protein family FlaC_arch PF05377.11 KPA42138.1 - 0.98 9.9 3.0 5.8 7.4 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Aft1_HRR PF11787.8 KPA42139.1 - 3.4e-30 105.0 10.5 3.4e-30 105.0 10.5 4.1 4 2 0 4 4 4 1 Aft1 HRR domain Aft1_HRA PF11786.8 KPA42139.1 - 1.2e-24 86.4 9.1 1.2e-24 86.4 9.1 3.4 3 1 1 4 4 4 1 Aft1 HRA domain Aft1_OSA PF11785.8 KPA42139.1 - 3.3e-22 78.7 7.4 3.3e-22 78.7 7.4 4.0 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 KPA42139.1 - 7.7e-13 48.3 5.5 1.2e-12 47.7 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPA42139.1 - 5.3e-06 26.4 5.9 9.4e-06 25.6 5.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KPA42139.1 - 0.00079 19.9 2.8 0.0018 18.7 2.8 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Macoilin PF09726.9 KPA42139.1 - 0.72 8.3 8.8 1.1 7.8 8.8 1.3 1 0 0 1 1 1 0 Macoilin family ASD2 PF08687.11 KPA42139.1 - 9.7 5.6 11.0 0.93 9.0 6.2 1.6 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 zf-CCHC PF00098.23 KPA42140.1 - 5.4e-51 168.5 90.0 4.3e-07 29.7 3.0 10.3 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_2 PF13696.6 KPA42140.1 - 6.1e-12 45.1 76.0 0.0077 16.0 1.4 9.6 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_4 PF14392.6 KPA42140.1 - 4.8e-10 39.0 61.0 0.14 11.9 0.3 10.1 10 0 0 10 10 10 8 Zinc knuckle zf-C2H2_10 PF16588.5 KPA42140.1 - 6.3e-05 22.6 7.8 0.00062 19.4 1.8 9.5 10 0 0 10 10 10 5 C2H2 zinc-finger zf-CCHC_3 PF13917.6 KPA42140.1 - 0.014 15.4 1.3 0.014 15.4 1.3 10.0 5 3 5 10 10 10 0 Zinc knuckle zinc_ribbon_4 PF13717.6 KPA42140.1 - 0.028 14.4 4.6 0.028 14.4 4.6 7.7 6 3 3 9 9 9 0 zinc-ribbon domain zf-CCHC_6 PF15288.6 KPA42140.1 - 0.29 11.0 72.6 0.11 12.4 0.8 10.2 8 2 2 10 10 10 0 Zinc knuckle CIAPIN1 PF05093.13 KPA42141.1 - 6.4e-42 142.1 2.4 9.6e-42 141.6 2.4 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KPA42141.1 - 3.1e-33 114.8 0.0 4.7e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Peptidase_S10 PF00450.22 KPA42142.1 - 1.6e-114 383.6 0.0 2.1e-114 383.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4381 PF14316.6 KPA42142.1 - 0.093 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RNA_Me_trans PF04252.13 KPA42143.1 - 3.9e-84 281.2 0.0 4.4e-84 281.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Formyl_trans_N PF00551.19 KPA42144.1 - 2e-21 76.5 0.0 4.6e-21 75.4 0.0 1.6 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.18 KPA42144.1 - 1.5e-05 25.2 0.1 2.9e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain PASTA PF03793.19 KPA42144.1 - 0.19 11.6 0.1 0.64 9.9 0.1 1.9 1 0 0 1 1 1 0 PASTA domain Med1 PF10744.9 KPA42145.1 - 3.8e-115 385.3 0.0 4.7e-115 384.9 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 CMV_1a PF12467.8 KPA42146.1 - 0.15 12.4 2.2 0.44 10.9 2.2 1.9 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family SUR7 PF06687.12 KPA42147.1 - 1.4e-19 70.6 9.2 1.9e-19 70.2 9.2 1.2 1 0 0 1 1 1 1 SUR7/PalI family TMEM52 PF14979.6 KPA42147.1 - 0.0072 16.2 0.1 0.0072 16.2 0.1 1.6 2 0 0 2 2 2 1 Transmembrane 52 Rhabdo_glycop PF00974.18 KPA42147.1 - 0.05 12.0 0.1 0.076 11.5 0.1 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein LapA_dom PF06305.11 KPA42147.1 - 0.12 12.2 0.5 0.12 12.2 0.5 2.9 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain MscL PF01741.18 KPA42147.1 - 0.17 12.2 2.5 14 6.0 0.5 2.2 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL Herpes_gE PF02480.16 KPA42147.1 - 0.23 10.2 3.4 0.13 11.0 1.2 1.7 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KPA42147.1 - 0.6 11.0 0.1 0.6 11.0 0.1 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Trp_oprn_chp PF09534.10 KPA42147.1 - 1.2 8.9 7.2 0.3 10.9 0.9 2.6 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1772 PF08592.11 KPA42147.1 - 1.8 8.9 7.7 0.31 11.4 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DuoxA PF10204.9 KPA42147.1 - 5.1 6.0 10.4 0.66 8.9 5.4 1.9 2 0 0 2 2 2 0 Dual oxidase maturation factor DUF373 PF04123.13 KPA42147.1 - 7.6 5.9 10.2 0.3 10.5 4.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Methyltransf_3 PF01596.17 KPA42148.1 - 1e-35 122.8 0.0 2.4e-35 121.6 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KPA42148.1 - 2.1e-10 41.6 0.0 3.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KPA42148.1 - 3.1e-09 36.9 0.0 4.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KPA42148.1 - 3.6e-07 30.1 0.0 4.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA42148.1 - 5.8e-05 23.7 0.0 0.0001 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ORMDL PF04061.14 KPA42150.1 - 1.1e-56 190.4 3.1 1.3e-56 190.1 3.1 1.1 1 0 0 1 1 1 1 ORMDL family zf-CCHC PF00098.23 KPA42151.1 - 0.00038 20.4 27.5 0.013 15.5 2.1 4.7 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_5 PF14787.6 KPA42151.1 - 2 8.2 16.9 4.1 7.2 0.4 4.5 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger DSBA PF01323.20 KPA42153.1 - 1.5e-19 70.6 0.0 1.8e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain RRM_1 PF00076.22 KPA42154.1 - 6.4e-16 57.9 0.1 4.4e-11 42.4 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KPA42154.1 - 0.0039 17.0 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KPA42154.1 - 0.045 13.9 0.2 0.37 10.9 0.1 2.4 2 0 0 2 2 2 0 RNA recognition motif RRM_3 PF08777.11 KPA42154.1 - 0.55 10.3 7.3 0.92 9.6 5.1 2.6 1 1 1 2 2 2 0 RNA binding motif Cut8 PF08559.10 KPA42155.1 - 5.5e-78 261.9 0.0 6.9e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Rad52_Rad22 PF04098.15 KPA42156.1 - 1.7e-60 203.4 0.1 2.4e-60 202.9 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein TPR_12 PF13424.6 KPA42157.1 - 1.7e-07 31.5 2.4 0.027 14.7 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KPA42157.1 - 2.3e-05 24.0 5.5 0.34 10.8 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPA42157.1 - 0.00016 21.5 8.4 0.019 15.0 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPA42157.1 - 0.0014 18.5 0.1 0.46 10.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA42157.1 - 0.12 12.7 3.3 18 5.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1129 PF06570.11 KPA42157.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Cyt-b5 PF00173.28 KPA42158.1 - 1.6e-12 47.3 0.1 1.8e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2 PF00096.26 KPA42159.1 - 3e-11 43.1 45.8 3e-05 24.2 3.8 7.2 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA42159.1 - 1.4e-08 34.9 44.8 0.0087 16.8 3.3 7.5 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA42159.1 - 0.062 13.6 0.2 0.062 13.6 0.2 6.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPA42159.1 - 0.22 11.9 21.8 1.5 9.3 0.1 6.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KPA42159.1 - 0.72 10.0 10.8 1.1 9.4 0.3 2.7 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KPA42159.1 - 6.4 6.9 19.0 0.077 13.0 2.2 4.4 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KPA42160.1 - 0.00023 21.7 15.9 0.34 11.9 0.7 4.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA42160.1 - 0.00085 19.6 15.0 2 9.0 1.6 4.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KPA42160.1 - 0.033 14.5 1.3 0.34 11.3 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 KPA42160.1 - 0.2 11.6 3.2 5.6 7.0 0.3 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger AIM24 PF01987.17 KPA42162.1 - 5e-51 173.4 1.1 7.3e-51 172.8 1.1 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Terpene_synth_C PF03936.16 KPA42163.1 - 7.4e-07 28.8 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Glyco_hydro_18 PF00704.28 KPA42164.1 - 4.1e-74 250.1 0.0 5e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KPA42164.1 - 2.4e-07 31.1 13.5 7.5e-07 29.5 13.5 1.8 1 0 0 1 1 1 1 Chitin recognition protein CaMKII_AD PF08332.10 KPA42164.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain DUF4267 PF14087.6 KPA42165.1 - 1.3e-15 57.4 2.0 1.6e-15 57.2 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DoxX_3 PF13781.6 KPA42165.1 - 0.00033 21.2 0.5 0.00049 20.7 0.2 1.5 1 1 0 1 1 1 1 DoxX-like family ATG13 PF10033.9 KPA42166.1 - 7e-76 255.1 0.0 1.1e-75 254.4 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 VHS PF00790.19 KPA42167.1 - 8.4e-37 126.2 0.1 2.4e-36 124.7 0.1 1.7 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KPA42167.1 - 1.2e-15 56.8 0.4 2.8e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KPA42167.1 - 6.8e-15 54.5 0.0 1.5e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KPA42167.1 - 1.9e-14 53.3 0.1 4.5e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KPA42167.1 - 2.2e-10 40.7 1.6 2.2e-10 40.7 1.6 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 KPA42167.1 - 0.0055 16.5 3.8 0.016 15.1 3.8 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif S1-P1_nuclease PF02265.16 KPA42169.1 - 9.1e-69 232.1 0.2 1e-68 231.9 0.2 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PQ-loop PF04193.14 KPA42170.1 - 1.2e-36 124.3 11.7 2.3e-19 68.9 0.1 3.0 3 0 0 3 3 3 2 PQ loop repeat Semialdhyde_dhC PF02774.18 KPA42171.1 - 5.6e-37 127.6 0.0 7.4e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KPA42171.1 - 1.7e-30 105.9 0.0 7.2e-30 103.9 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KPA42171.1 - 0.11 13.2 0.0 0.32 11.7 0.0 1.9 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 KPA42171.1 - 0.16 12.3 0.0 0.58 10.4 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain zf-RING_2 PF13639.6 KPA42172.1 - 1.5e-12 47.7 5.4 2.5e-12 46.9 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KPA42172.1 - 4.6e-09 36.4 3.2 8.5e-09 35.6 2.3 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KPA42172.1 - 6.8e-09 35.4 4.5 1.2e-08 34.6 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA42172.1 - 2.1e-08 33.9 3.5 3.5e-08 33.2 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KPA42172.1 - 3.1e-08 33.5 0.0 6.5e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-RING_11 PF17123.5 KPA42172.1 - 5.4e-08 32.4 3.0 5.4e-08 32.4 3.0 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_5 PF14634.6 KPA42172.1 - 6.8e-07 29.1 2.6 1.1e-06 28.5 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KPA42172.1 - 1.2e-05 25.1 3.0 1.8e-05 24.5 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA42172.1 - 2.9e-05 24.0 2.5 6.4e-05 22.9 0.6 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KPA42172.1 - 0.0012 18.9 1.2 0.0024 17.9 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KPA42172.1 - 0.011 15.6 3.0 0.02 14.8 3.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KPA42172.1 - 0.031 14.4 3.9 0.095 12.9 4.0 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KPA42172.1 - 0.13 12.4 2.5 0.35 11.1 2.5 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KPA42172.1 - 0.2 11.3 3.5 0.41 10.3 3.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pep1_7 PF17232.2 KPA42172.1 - 0.35 11.4 3.2 12 6.4 0.0 3.6 2 0 0 2 2 2 0 Elicitor peptide 1-7 zf-RING_4 PF14570.6 KPA42172.1 - 0.52 10.1 2.6 0.97 9.3 2.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KPA42172.1 - 0.52 10.5 3.7 1.1 9.5 3.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KPA42172.1 - 0.55 10.6 3.4 1 9.7 3.4 1.5 1 0 0 1 1 1 0 RING-like domain DUF4083 PF13314.6 KPA42172.1 - 0.61 10.1 4.1 10 6.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) PHD PF00628.29 KPA42172.1 - 0.73 9.8 2.8 1.4 8.9 2.8 1.5 1 0 0 1 1 1 0 PHD-finger CPSase_L_D3 PF02787.19 KPA42173.1 - 0.4 11.0 1.8 0.44 10.9 0.2 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain KASH_CCD PF14662.6 KPA42174.1 - 0.038 13.8 22.3 0.18 11.6 11.8 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF2577 PF10844.8 KPA42174.1 - 0.12 12.7 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) ABC_tran_CTD PF16326.5 KPA42174.1 - 0.14 12.4 19.6 0.034 14.4 10.9 3.7 1 1 2 3 3 3 0 ABC transporter C-terminal domain MCC-bdg_PDZ PF10506.9 KPA42174.1 - 0.18 11.8 7.6 5.5 7.1 0.0 3.5 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF948 PF06103.11 KPA42174.1 - 0.36 11.1 2.8 0.8 10.0 0.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.11 KPA42174.1 - 0.56 10.0 7.8 1.9 8.3 0.8 2.7 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) HAUS-augmin3 PF14932.6 KPA42174.1 - 0.58 9.7 17.4 0.12 11.9 10.0 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 BLOC1_2 PF10046.9 KPA42174.1 - 0.63 10.4 11.1 0.094 13.0 4.9 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.12 KPA42174.1 - 1.6 7.2 10.5 2.5 6.5 10.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 KPA42174.1 - 2 8.8 19.8 9.2 6.7 19.8 2.1 1 1 0 1 1 1 0 Fez1 Viral_P18 PF04521.13 KPA42174.1 - 3.1 7.6 7.4 3.3 7.5 0.2 2.6 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein CENP-F_leu_zip PF10473.9 KPA42174.1 - 3.1 7.8 24.0 0.55 10.3 10.6 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KPA42174.1 - 3.8 7.6 18.7 1.4 9.0 9.2 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KPA42174.1 - 4.5 6.5 16.0 1.2 8.4 12.9 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 KPA42174.1 - 4.7 7.5 18.8 1 9.7 2.6 3.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 KPA42174.1 - 5.3 5.8 25.8 0.31 9.9 8.1 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein OmpH PF03938.14 KPA42174.1 - 5.4 7.4 24.8 0.4 11.0 6.3 2.9 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) YabA PF06156.13 KPA42174.1 - 6.9 7.4 17.8 7.7 7.2 3.2 3.4 1 1 2 3 3 3 0 Initiation control protein YabA Zn_clus PF00172.18 KPA42175.1 - 4e-08 33.3 11.6 6.8e-08 32.5 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup54_C PF18437.1 KPA42175.1 - 0.36 10.8 2.3 0.82 9.6 2.3 1.6 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain LANC_like PF05147.13 KPA42176.1 - 2.8e-24 85.4 0.0 3.1e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein EI24 PF07264.11 KPA42177.1 - 1.8e-12 47.8 2.3 5.1e-12 46.4 2.3 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Pyrid_oxidase_2 PF13883.6 KPA42178.1 - 5 7.1 9.0 0.47 10.4 3.0 2.5 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase QCR10 PF09796.9 KPA42179.1 - 0.093 12.8 0.9 0.24 11.5 0.5 1.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) rhaM PF05336.13 KPA42180.1 - 1.1e-36 125.2 0.6 1.2e-36 125.0 0.6 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase EGF PF00008.27 KPA42181.1 - 0.066 13.5 8.0 0.12 12.8 8.0 1.4 1 0 0 1 1 1 0 EGF-like domain EGF_alliinase PF04863.13 KPA42181.1 - 1.7 9.1 7.1 3.9 8.0 7.1 1.6 1 0 0 1 1 1 0 Alliinase EGF-like domain hEGF PF12661.7 KPA42181.1 - 3.5 8.4 7.8 7.6 7.3 7.8 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.13 KPA42181.1 - 6 7.3 13.4 12 6.4 13.4 1.5 1 0 0 1 1 1 0 EGF-like domain Carboxyl_trans PF01039.22 KPA42182.1 - 1.6e-134 449.2 0.1 2.3e-134 448.7 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KPA42182.1 - 0.0012 18.4 0.1 1.3 8.4 0.1 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Flagellar_rod PF05149.12 KPA42182.1 - 0.16 11.4 1.3 0.22 11.0 0.8 1.4 2 0 0 2 2 2 0 Paraflagellar rod protein Acyl-CoA_dh_1 PF00441.24 KPA42183.1 - 9.7e-42 142.7 0.2 1.8e-41 141.8 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPA42183.1 - 7.3e-32 110.4 0.2 1.5e-31 109.4 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KPA42183.1 - 4.2e-28 97.4 0.2 7.8e-28 96.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPA42183.1 - 3e-14 53.5 0.0 7.2e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KPA42183.1 - 1.9e-05 24.5 0.1 4.5e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short_C2 PF13561.6 KPA42184.1 - 1.8e-55 188.1 0.0 2.4e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA42184.1 - 6e-39 133.5 0.1 7.9e-39 133.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA42184.1 - 2.2e-12 47.2 0.1 3.2e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KPA42184.1 - 0.099 12.0 0.0 10 5.4 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1752 PF08550.10 KPA42185.1 - 0.023 14.5 0.6 0.054 13.3 0.6 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) zf-Sec23_Sec24 PF04810.15 KPA42187.1 - 0.2 11.8 0.2 0.42 10.7 0.2 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger PHD PF00628.29 KPA42188.1 - 2e-09 37.2 2.2 4.8e-09 36.0 2.2 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KPA42188.1 - 0.013 15.1 2.2 0.021 14.4 2.2 1.4 1 0 0 1 1 1 0 PHD-finger CEBP_ZZ PF16366.5 KPA42188.1 - 0.055 13.7 1.4 0.12 12.6 1.4 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain UIM PF02809.20 KPA42188.1 - 0.18 11.8 2.4 0.71 9.9 2.4 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif MMR_HSR1 PF01926.23 KPA42189.1 - 1.6e-11 44.3 0.0 3.2e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA42189.1 - 1.2e-05 25.3 0.3 4.2e-05 23.5 0.1 2.0 2 1 0 2 2 2 1 RsgA GTPase Septin PF00735.18 KPA42189.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 KPA42189.1 - 0.011 15.2 0.1 0.025 14.1 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Glyco_tran_10_N PF17039.5 KPA42189.1 - 0.064 13.7 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal AAA_16 PF13191.6 KPA42189.1 - 0.094 13.1 0.0 0.4 11.1 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 KPA42189.1 - 0.11 12.6 0.1 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Dynamin family HCO3_cotransp PF00955.21 KPA42190.1 - 2.9e-72 244.1 5.1 3.6e-37 128.4 0.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family adh_short PF00106.25 KPA42190.1 - 9.3e-23 80.7 0.0 1.6e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA42190.1 - 2.6e-16 59.9 0.0 9.4e-16 58.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 KPA42192.1 - 9.8e-14 51.5 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA42192.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPA42192.1 - 0.014 16.5 0.0 0.023 15.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HTH_38 PF13936.6 KPA42192.1 - 0.13 12.1 0.1 3.1 7.6 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain PI3Ka PF00613.20 KPA42193.1 - 2.2e-58 196.7 0.6 4e-58 195.9 0.6 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KPA42193.1 - 1.7e-45 155.8 0.1 1e-29 104.1 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KPA42193.1 - 1.7e-30 105.8 0.0 3.3e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 KPA42193.1 - 0.00016 21.9 0.0 0.00047 20.4 0.0 1.8 2 0 0 2 2 2 1 C2 domain MFS_1 PF07690.16 KPA42195.1 - 1.7e-20 73.3 44.6 3.3e-09 36.1 20.8 3.9 2 1 2 4 4 4 3 Major Facilitator Superfamily DUF4381 PF14316.6 KPA42197.1 - 0.11 12.7 0.7 0.19 12.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) OATP PF03137.20 KPA42197.1 - 0.74 8.0 4.8 0.22 9.8 1.7 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family UPF0370 PF13980.6 KPA42197.1 - 0.95 9.5 3.9 1.5 8.9 3.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) hDGE_amylase PF14701.6 KPA42198.1 - 8.2e-179 595.3 0.0 1.1e-178 594.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KPA42198.1 - 3.9e-117 391.4 0.3 7.3e-117 390.5 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KPA42198.1 - 2.8e-88 295.9 0.0 1e-87 294.0 0.0 1.9 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KPA42198.1 - 1.7e-30 105.0 0.0 3.9e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme DUF1687 PF07955.11 KPA42198.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Coiled-coil_56 PF09813.9 KPA42198.1 - 0.17 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 TRM PF02005.16 KPA42199.1 - 1.9e-104 349.8 0.0 1.9e-92 310.4 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_3 PF01596.17 KPA42199.1 - 0.056 12.6 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DAGK_cat PF00781.24 KPA42200.1 - 2e-09 37.1 0.0 4.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PH_TFIIH PF08567.11 KPA42200.1 - 0.095 13.0 0.2 0.26 11.7 0.2 1.7 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Peptidase_C25 PF01364.18 KPA42200.1 - 0.17 11.1 0.0 0.29 10.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase family C25 ABC_tran PF00005.27 KPA42201.1 - 3.9e-44 150.5 5.0 1e-21 77.8 0.2 3.6 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 KPA42201.1 - 2.5e-12 47.2 2.1 0.00062 19.7 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPA42201.1 - 3.6e-09 36.4 0.5 0.0058 16.1 0.0 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPA42201.1 - 2.2e-07 30.5 0.3 0.00091 18.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KPA42201.1 - 3.7e-07 30.2 0.1 0.061 13.4 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 KPA42201.1 - 1.4e-06 28.3 4.2 1.4e-06 28.3 4.2 2.1 2 0 0 2 2 1 1 ABC transporter RsgA_GTPase PF03193.16 KPA42201.1 - 2.2e-06 27.7 1.7 0.014 15.3 0.4 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KPA42201.1 - 2.5e-06 27.9 2.4 0.00046 20.5 0.2 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPA42201.1 - 3.6e-06 26.8 0.6 0.11 12.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KPA42201.1 - 8.8e-06 26.3 0.1 0.25 11.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KPA42201.1 - 1.4e-05 25.6 1.6 0.13 12.6 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 KPA42201.1 - 1.8e-05 23.9 1.5 0.015 14.3 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KPA42201.1 - 3.4e-05 24.1 3.2 0.18 12.1 0.3 3.3 3 2 0 3 3 2 2 AAA domain AAA PF00004.29 KPA42201.1 - 0.0001 22.7 0.2 0.029 14.8 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KPA42201.1 - 0.00021 21.5 2.8 0.42 10.8 0.1 3.3 4 0 0 4 4 3 2 AAA domain AAA_27 PF13514.6 KPA42201.1 - 0.00061 19.5 0.2 0.027 14.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KPA42201.1 - 0.00082 19.3 0.1 0.1 12.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 KPA42201.1 - 0.00099 19.2 6.3 0.41 10.7 0.0 2.9 3 1 0 3 3 2 2 Dynamin family DUF815 PF05673.13 KPA42201.1 - 0.0019 17.4 0.1 0.58 9.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KPA42201.1 - 0.0021 17.4 0.3 0.95 8.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 KPA42201.1 - 0.0027 18.1 0.0 0.42 11.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.17 KPA42201.1 - 0.0036 17.4 11.3 0.25 11.4 0.1 4.0 3 1 1 4 4 4 2 Helicase HerA, central domain AAA_14 PF13173.6 KPA42201.1 - 0.0038 17.3 2.3 0.51 10.4 0.0 3.5 5 0 0 5 5 3 1 AAA domain Thymidylate_kin PF02223.17 KPA42201.1 - 0.0056 16.4 0.2 0.86 9.3 0.0 2.7 2 0 0 2 2 2 1 Thymidylate kinase NTPase_1 PF03266.15 KPA42201.1 - 0.0087 16.0 0.3 1.9 8.4 0.0 3.0 3 0 0 3 3 3 1 NTPase Roc PF08477.13 KPA42201.1 - 0.0092 16.2 0.5 7.6 6.8 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA42201.1 - 0.01 15.3 0.8 0.27 10.7 0.2 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family ATP-synt_ab PF00006.25 KPA42201.1 - 0.012 15.2 0.2 5.1 6.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KPA42201.1 - 0.016 14.7 0.4 0.21 11.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 KPA42201.1 - 0.017 15.1 1.1 0.45 10.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KPA42201.1 - 0.025 14.3 0.2 0.025 14.3 0.2 3.3 3 1 1 4 4 4 0 AAA ATPase domain AAA_24 PF13479.6 KPA42201.1 - 0.025 14.3 4.2 0.96 9.1 0.0 3.6 4 0 0 4 4 3 0 AAA domain Viral_helicase1 PF01443.18 KPA42201.1 - 0.026 14.3 0.1 6.3 6.5 0.0 3.0 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KPA42201.1 - 0.038 13.9 0.2 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 KPA42201.1 - 0.039 14.4 2.8 6.4 7.2 0.1 3.1 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 KPA42201.1 - 0.042 13.8 0.6 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KPA42201.1 - 0.046 13.3 0.6 12 5.5 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 KPA42201.1 - 0.066 12.0 1.7 0.25 10.1 0.0 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Septin PF00735.18 KPA42201.1 - 0.087 12.1 0.2 5.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Septin DUF3710 PF12502.8 KPA42201.1 - 0.094 12.4 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) NYN PF01936.18 KPA42201.1 - 0.13 12.7 0.0 0.38 11.2 0.0 1.8 1 0 0 1 1 1 0 NYN domain Ploopntkinase1 PF18748.1 KPA42201.1 - 0.14 11.7 0.0 5.4 6.5 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 RuvA_C PF07499.13 KPA42201.1 - 0.23 11.9 1.8 29 5.2 0.0 3.7 4 0 0 4 4 3 0 RuvA, C-terminal domain NB-ARC PF00931.22 KPA42201.1 - 0.39 9.9 8.4 0.96 8.6 0.0 3.7 5 0 0 5 5 4 0 NB-ARC domain AAA_23 PF13476.6 KPA42201.1 - 0.9 10.0 22.8 5.1 7.5 8.0 4.1 3 1 0 3 3 3 0 AAA domain MobB PF03205.14 KPA42201.1 - 0.92 9.4 5.1 6.4 6.7 0.1 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 KPA42202.1 - 3.5e-47 160.3 0.0 9.4e-24 84.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KPA42202.1 - 3.8e-19 69.4 22.6 5.7e-13 49.1 0.3 3.5 2 1 1 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.6 KPA42202.1 - 4.3e-17 62.9 1.5 5.5e-05 23.1 0.0 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPA42202.1 - 1.3e-11 44.3 0.0 0.00014 21.4 0.0 3.4 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPA42202.1 - 8e-08 31.9 0.1 0.0054 16.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KPA42202.1 - 2.2e-06 27.7 0.3 0.0051 16.7 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 KPA42202.1 - 7.6e-05 23.0 0.0 0.048 13.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA42202.1 - 0.00012 22.5 0.2 0.3 11.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KPA42202.1 - 0.0002 21.9 0.0 0.42 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KPA42202.1 - 0.00025 21.1 0.2 0.42 10.7 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 KPA42202.1 - 0.00041 19.5 0.0 0.71 8.9 0.0 2.5 3 0 0 3 3 3 2 Type II/IV secretion system protein SbcCD_C PF13558.6 KPA42202.1 - 0.0018 18.5 0.0 0.3 11.4 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KPA42202.1 - 0.0029 17.4 0.0 0.079 12.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 KPA42202.1 - 0.008 16.2 1.0 4.1 7.4 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AAA_7 PF12775.7 KPA42202.1 - 0.012 15.2 0.0 4.6 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KPA42202.1 - 0.013 16.0 0.0 5.1 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KPA42202.1 - 0.017 14.4 0.0 0.052 12.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rad17 PF03215.15 KPA42202.1 - 0.019 14.9 0.0 3.4 7.6 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain AAA PF00004.29 KPA42202.1 - 0.12 12.8 0.3 3.6 8.0 0.1 3.3 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 KPA42202.1 - 0.14 11.7 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KPA42202.1 - 0.15 12.1 0.1 22 5.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KPA42202.1 - 0.16 12.1 0.0 6 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KPA42202.1 - 0.16 12.0 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain NTPase_1 PF03266.15 KPA42202.1 - 0.26 11.2 2.0 8.8 6.2 0.0 3.0 3 0 0 3 3 3 0 NTPase NDT80_PhoG PF05224.12 KPA42204.1 - 1.9e-46 158.7 0.1 2.5e-46 158.2 0.1 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pterin_bind PF00809.22 KPA42205.1 - 2.5e-81 272.9 0.0 3.3e-81 272.6 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KPA42205.1 - 9.7e-32 109.8 0.0 1.7e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF4141 PF13605.6 KPA42205.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) NMO PF03060.15 KPA42206.1 - 2.4e-57 194.8 0.4 3.3e-57 194.4 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KPA42206.1 - 3.5e-11 42.7 1.8 5.9e-11 42.0 1.8 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KPA42206.1 - 0.00021 20.4 3.6 0.00021 20.4 3.6 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KPA42206.1 - 0.014 14.6 0.5 0.022 14.0 0.5 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 KPA42206.1 - 0.11 11.6 2.6 0.22 10.6 2.6 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase HET PF06985.11 KPA42207.1 - 7.1e-09 36.2 0.0 8.6e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ArfGap PF01412.18 KPA42208.1 - 1.9e-35 121.4 0.2 3.3e-35 120.7 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.11 KPA42209.1 - 8.6e-43 145.7 0.0 1.1e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KPA42209.1 - 7.5e-06 25.7 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 zf-H2C2_2 PF13465.6 KPA42210.1 - 4.3e-10 39.6 19.4 1.8e-05 24.9 3.5 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KPA42210.1 - 1.5e-08 34.6 14.0 0.00041 20.6 4.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA42210.1 - 0.0053 17.5 17.5 0.047 14.6 3.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KPA42210.1 - 0.025 14.6 2.0 2.2 8.4 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA42210.1 - 0.048 14.0 0.4 0.048 14.0 0.4 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KPA42210.1 - 0.23 12.1 8.1 0.1 13.3 3.1 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF2225 PF09986.9 KPA42210.1 - 0.4 10.4 0.8 0.85 9.3 0.8 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-H2C2_5 PF13909.6 KPA42210.1 - 5.4 6.9 15.6 2.7 7.8 0.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain RecA PF00154.21 KPA42211.1 - 6e-08 32.5 0.0 1.2e-07 31.5 0.0 1.4 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 KPA42211.1 - 8.5e-07 28.5 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 KaiC Rad51 PF08423.11 KPA42211.1 - 5.6e-06 25.8 0.0 1.2e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Rad51 AAA_11 PF13086.6 KPA42211.1 - 0.00023 21.0 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KPA42211.1 - 0.001 18.7 0.2 0.0015 18.1 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KPA42211.1 - 0.009 15.8 0.0 0.014 15.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KPA42211.1 - 0.0096 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 KPA42211.1 - 0.01 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KPA42211.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KPA42211.1 - 0.013 16.0 0.0 0.018 15.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KPA42211.1 - 0.024 15.0 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DnaB_C PF03796.15 KPA42211.1 - 0.048 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_30 PF13604.6 KPA42211.1 - 0.092 12.5 0.5 0.21 11.3 0.5 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KPA42211.1 - 0.093 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KPA42211.1 - 0.095 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein RNA12 PF10443.9 KPA42211.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein Bromodomain PF00439.25 KPA42213.1 - 6.7e-16 58.1 0.0 1.6e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BTB PF00651.31 KPA42213.1 - 0.00013 22.2 0.0 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ACBP PF00887.19 KPA42215.1 - 2.8e-21 75.5 0.9 3.3e-21 75.3 0.9 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Pyr_redox_2 PF07992.14 KPA42216.1 - 1.1e-38 133.2 0.1 1.3e-38 132.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA42216.1 - 2.8e-06 27.8 0.1 3.6e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA42216.1 - 0.00012 21.4 0.2 0.00076 18.7 0.1 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPA42216.1 - 0.068 13.2 0.5 2.8 7.9 0.0 3.2 3 1 1 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KPA42216.1 - 0.13 11.3 0.2 1.2 8.1 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Tricorn_PDZ PF14685.6 KPA42216.1 - 0.13 12.2 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain End3 PF12761.7 KPA42217.1 - 5.5e-78 261.7 4.5 7.8e-78 261.2 4.5 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KPA42217.1 - 4.3e-50 168.0 0.0 7.5e-48 160.8 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KPA42217.1 - 3.5e-07 29.3 0.3 9.6e-07 27.9 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KPA42217.1 - 6.4e-06 26.5 0.1 3.7e-05 24.1 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KPA42217.1 - 0.00094 18.9 0.3 0.0041 16.9 0.3 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KPA42217.1 - 0.0015 18.3 0.1 0.0037 17.1 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KPA42217.1 - 0.025 14.1 0.2 0.069 12.7 0.2 1.7 1 0 0 1 1 1 0 EF hand DUF4201 PF13870.6 KPA42217.1 - 0.1 12.3 9.0 1.1 9.0 9.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Wtap PF17098.5 KPA42217.1 - 5.6 6.9 9.4 49 3.8 9.2 2.3 1 1 0 1 1 1 0 WTAP/Mum2p family EMP24_GP25L PF01105.24 KPA42217.1 - 7.8 6.4 10.5 11 5.9 2.9 2.9 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD NUDIX PF00293.28 KPA42218.1 - 3.4e-26 91.8 0.0 4.9e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_7 PF13508.7 KPA42219.1 - 2.6e-06 27.8 0.1 4.5e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA42219.1 - 3.5e-06 27.1 0.1 5.8e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA42219.1 - 3.8e-06 26.9 0.1 7.2e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA42219.1 - 1.6e-05 25.1 0.1 2.6e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KPA42219.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KPA42219.1 - 0.0081 16.3 0.1 0.027 14.6 0.0 2.0 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase RPA_C PF08784.11 KPA42220.1 - 1.5e-19 70.6 1.3 2.4e-19 69.9 0.1 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KPA42220.1 - 1e-08 35.1 0.2 2.3e-08 33.9 0.1 1.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Lon_C PF05362.13 KPA42221.1 - 5.9e-68 228.4 0.4 1.2e-67 227.5 0.4 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KPA42221.1 - 4.7e-27 95.2 0.0 9e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KPA42221.1 - 8e-23 81.3 0.0 1.7e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KPA42221.1 - 5.8e-08 32.8 0.0 2.1e-07 31.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KPA42221.1 - 3.2e-07 30.2 0.6 1.6e-06 27.9 0.0 2.4 3 0 0 3 3 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 KPA42221.1 - 1.7e-06 28.2 0.2 8.5e-06 26.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KPA42221.1 - 5e-06 27.0 0.1 3.3e-05 24.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 KPA42221.1 - 3.8e-05 23.6 0.0 0.00012 21.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA42221.1 - 6.8e-05 23.2 0.0 0.01 16.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KPA42221.1 - 0.00028 20.7 0.1 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KPA42221.1 - 0.00056 19.7 0.1 0.0026 17.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 KPA42221.1 - 0.00058 19.2 0.1 0.0012 18.1 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KPA42221.1 - 0.012 15.7 0.0 0.035 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPA42221.1 - 0.017 15.6 0.0 0.056 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KPA42221.1 - 0.033 14.1 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KPA42221.1 - 0.04 13.9 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPA42221.1 - 0.047 14.1 0.0 0.22 11.9 0.0 2.2 2 0 0 2 2 1 0 RNA helicase NTPase_1 PF03266.15 KPA42221.1 - 0.049 13.5 0.1 0.17 11.8 0.1 2.0 1 1 0 1 1 1 0 NTPase AAA_25 PF13481.6 KPA42221.1 - 0.053 13.1 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KPA42221.1 - 0.067 13.2 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KPA42221.1 - 0.15 11.4 0.2 0.35 10.2 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KPA42221.1 - 0.38 11.2 0.0 0.38 11.2 0.0 3.3 1 1 1 2 2 1 0 AAA domain AAA_11 PF13086.6 KPA42221.1 - 0.49 10.1 0.0 0.49 10.1 0.0 2.3 1 1 1 2 2 1 0 AAA domain BLACT_WH PF17778.1 KPA42222.1 - 1.3e-18 66.6 0.0 7.5e-18 64.3 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KPA42222.1 - 3.3e-16 59.9 2.5 3.1e-14 53.4 2.5 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPA42222.1 - 2.7e-06 27.1 0.3 5e-06 26.2 0.3 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KPA42222.1 - 0.0086 16.0 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain UCH PF00443.29 KPA42223.1 - 1.3e-47 162.4 5.2 1.7e-47 162.1 5.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPA42223.1 - 2.9e-31 109.2 9.8 4.6e-31 108.6 9.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KPA42223.1 - 0.00015 22.0 0.8 0.00015 22.0 0.8 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein DnaJ_CXXCXGXG PF00684.19 KPA42223.1 - 2.2 8.7 13.1 1.3 9.4 1.2 3.5 3 0 0 3 3 3 0 DnaJ central domain N6-adenineMlase PF10237.9 KPA42224.1 - 9.1e-46 155.6 0.0 1.8e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase NmrA PF05368.13 KPA42224.1 - 6.1e-16 58.7 0.0 8.7e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA42224.1 - 2e-14 53.9 0.0 5.7e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KPA42224.1 - 7.4e-13 48.5 0.1 1.7e-12 47.4 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA42224.1 - 5.3e-09 35.5 0.0 1.5e-08 34.0 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KPA42224.1 - 1.3e-06 28.1 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KPA42224.1 - 0.00016 21.2 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA42224.1 - 0.0028 17.3 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 KPA42224.1 - 0.015 14.4 0.0 0.28 10.2 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 KPA42224.1 - 0.024 13.8 0.4 2.4 7.2 0.0 2.5 1 1 0 2 2 2 0 Male sterility protein PCI PF01399.27 KPA42225.1 - 2e-09 37.9 0.0 4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KPA42225.1 - 2.2e-06 27.1 0.7 4.6e-06 26.1 0.7 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Gaa1 PF04114.14 KPA42226.1 - 1.8e-168 561.6 2.7 2.2e-168 561.4 2.7 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.22 KPA42227.1 - 2.8e-15 56.6 9.5 2.8e-15 56.6 9.5 1.5 2 0 0 2 2 2 1 Rhomboid family Aconitase PF00330.20 KPA42228.1 - 4.5e-146 487.5 0.0 5.6e-146 487.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KPA42228.1 - 3.9e-43 146.9 0.0 6.9e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 KPA42229.1 - 2.6e-10 40.3 1.2 4.4e-10 39.6 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KPA42229.1 - 0.0072 16.1 0.2 0.012 15.4 0.2 1.3 1 0 0 1 1 1 1 U1 zinc finger Tna_leader PF08053.11 KPA42229.1 - 0.017 15.0 0.3 0.032 14.2 0.3 1.4 1 0 0 1 1 1 0 Tryptophanase operon leader peptide zf-met PF12874.7 KPA42229.1 - 0.018 15.4 0.9 0.036 14.5 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KPA42229.1 - 0.023 15.5 0.5 0.061 14.2 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KPA42229.1 - 0.052 13.9 1.0 0.24 11.8 0.8 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) GH-E PF14410.6 KPA42229.1 - 0.071 13.5 0.1 0.25 11.7 0.0 1.8 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues zf-SCNM1 PF15803.5 KPA42229.1 - 0.094 12.4 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 DASH_Dam1 PF08653.10 KPA42230.1 - 7.7e-28 96.1 2.1 1e-27 95.6 2.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.20 KPA42231.1 - 1.1e-42 145.4 0.0 2.6e-42 144.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KPA42231.1 - 6.7e-15 55.0 0.2 6.7e-15 55.0 0.2 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KPA42231.1 - 4.4e-09 36.6 0.0 7.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DNA_pol_A_exoN PF18305.1 KPA42231.1 - 0.087 13.1 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain HIT PF01230.23 KPA42232.1 - 4.8e-22 78.5 0.0 6.5e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KPA42232.1 - 1.9e-12 47.7 0.0 2.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KPA42232.1 - 4.7e-05 23.3 0.2 7.3e-05 22.6 0.0 1.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Mog1 PF04603.12 KPA42233.1 - 2.7e-40 137.9 0.0 3.3e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SprT-like PF10263.9 KPA42234.1 - 1.1e-35 121.9 0.6 2.2e-35 121.0 0.6 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KPA42234.1 - 2.9e-08 33.5 2.1 6.6e-08 32.3 2.1 1.7 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KPA42234.1 - 0.0087 16.2 0.9 0.021 14.9 0.9 1.5 1 0 0 1 1 1 1 Zinc ribbon domain DUF4379 PF14311.6 KPA42234.1 - 0.59 10.5 3.2 0.71 10.3 1.3 2.2 2 0 0 2 2 2 0 Probable Zinc-ribbon domain zinc_ribbon_5 PF13719.6 KPA42234.1 - 1.6 8.5 6.5 0.67 9.8 1.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Glucan_synthase PF02364.15 KPA42235.1 - 0 1358.6 0.2 0 1357.2 0.0 1.7 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KPA42235.1 - 2.9e-43 147.3 1.1 9.5e-43 145.6 1.1 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 MerT PF02411.15 KPA42235.1 - 0.15 12.1 3.4 0.6 10.1 3.4 2.1 1 0 0 1 1 1 0 MerT mercuric transport protein LcnG-beta PF11632.8 KPA42235.1 - 7.1 6.7 5.9 13 5.8 3.9 2.3 2 0 0 2 2 2 0 Lactococcin G-beta Aminotran_1_2 PF00155.21 KPA42236.1 - 5e-36 124.6 0.0 6e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KPA42236.1 - 9.6e-05 21.1 0.0 0.00021 20.0 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KPA42236.1 - 0.0023 16.7 0.0 0.0047 15.7 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain SnAPC_2_like PF11035.8 KPA42236.1 - 0.098 12.8 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Glyco_hydro_17 PF00332.18 KPA42237.1 - 1.1e-09 38.4 0.2 1.2e-08 35.0 0.0 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 CBS PF00571.28 KPA42239.1 - 1.3e-18 67.2 8.8 1.1e-06 28.9 0.2 5.7 5 1 0 5 5 5 5 CBS domain HEAT_EZ PF13513.6 KPA42240.1 - 2.6e-22 78.9 12.1 6e-11 42.6 0.4 8.2 6 1 2 8 8 8 3 HEAT-like repeat Importin_rep_5 PF18816.1 KPA42240.1 - 7.8e-22 77.3 1.9 7.8e-22 77.3 1.9 3.2 3 0 0 3 3 3 1 Importin repeat HEAT PF02985.22 KPA42240.1 - 2.3e-19 67.8 15.4 0.0023 18.0 0.0 11.6 12 0 0 12 12 9 3 HEAT repeat HEAT_2 PF13646.6 KPA42240.1 - 1.4e-17 63.9 15.6 5.7e-05 23.4 0.0 8.2 3 3 4 7 7 7 6 HEAT repeats Importin_rep_6 PF18829.1 KPA42240.1 - 2.8e-13 49.9 3.9 1.2e-12 47.9 0.2 3.3 3 0 0 3 3 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KPA42240.1 - 1e-11 45.2 0.3 0.023 15.3 0.0 7.8 5 2 4 9 9 7 2 Vacuolar 14 Fab1-binding region Importin_rep_4 PF18808.1 KPA42240.1 - 1.4e-10 41.3 14.4 5.7e-06 26.5 0.1 6.8 5 2 2 7 7 7 2 Importin repeat RIX1 PF08167.12 KPA42240.1 - 1.1e-09 38.3 0.0 0.0013 18.5 0.1 5.3 5 1 1 6 6 5 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 KPA42240.1 - 1.6e-08 34.8 1.6 1.3 9.0 0.1 6.0 4 3 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KPA42240.1 - 3.9e-08 33.1 0.2 0.0013 18.4 0.1 5.7 4 1 2 6 6 6 1 CLASP N terminal MMS19_C PF12460.8 KPA42240.1 - 7.7e-06 25.3 0.1 7.7e-06 25.3 0.1 4.5 5 1 0 5 5 5 1 RNAPII transcription regulator C-terminal DRIM PF07539.12 KPA42240.1 - 7.4e-05 21.3 10.0 0.0079 14.6 0.5 4.4 3 2 1 4 4 4 2 Down-regulated in metastasis Xpo1 PF08389.12 KPA42240.1 - 9.3e-05 22.5 0.7 0.0022 18.0 0.0 3.6 3 1 0 3 3 3 1 Exportin 1-like protein DUF3535 PF12054.8 KPA42240.1 - 0.00089 18.6 1.5 0.0044 16.3 0.4 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF3535) DUF3385 PF11865.8 KPA42240.1 - 0.0012 18.8 9.6 0.14 12.1 0.0 6.2 5 2 0 7 7 7 1 Domain of unknown function (DUF3385) IBN_N PF03810.19 KPA42240.1 - 0.0017 18.2 0.6 0.034 14.0 0.1 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 KPA42240.1 - 0.0023 18.1 3.1 0.32 11.2 0.5 4.9 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 KPA42240.1 - 0.0028 17.0 5.6 0.072 12.4 0.2 3.0 3 1 0 3 3 3 1 V-ATPase subunit H DUF4042 PF13251.6 KPA42240.1 - 0.0046 16.7 0.2 14 5.3 0.0 4.9 4 1 1 5 5 5 0 Domain of unknown function (DUF4042) CAS_CSE1 PF03378.15 KPA42240.1 - 0.0097 14.4 3.0 3 6.2 0.1 4.2 3 1 0 4 4 4 1 CAS/CSE protein, C-terminus DNA_alkylation PF08713.11 KPA42240.1 - 0.011 15.5 0.5 0.1 12.3 0.0 2.8 3 0 0 3 3 3 0 DNA alkylation repair enzyme TFCD_C PF12612.8 KPA42240.1 - 0.016 15.1 0.1 0.5 10.2 0.0 3.3 1 1 1 2 2 2 0 Tubulin folding cofactor D C terminal Cohesin_HEAT PF12765.7 KPA42240.1 - 0.041 14.2 0.3 9 6.7 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Dopey_N PF04118.14 KPA42240.1 - 0.045 12.9 2.9 5.5 6.0 0.0 3.9 3 1 1 4 4 4 0 Dopey, N-terminal Arm PF00514.23 KPA42240.1 - 0.055 13.5 11.7 6.9 6.9 0.0 5.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 KPA42240.1 - 0.058 13.3 0.9 6 6.8 0.0 3.7 3 1 0 3 3 2 0 Domain of unknown function (DUF3361) Peptidase_M9_N PF08453.10 KPA42240.1 - 0.066 12.9 2.7 17 5.1 0.0 3.9 3 1 1 4 4 4 0 Peptidase family M9 N-terminal Telomere_reg-2 PF10193.9 KPA42240.1 - 0.094 13.2 11.4 0.067 13.6 2.0 4.4 4 2 0 4 4 4 0 Telomere length regulation protein MMS19_N PF14500.6 KPA42240.1 - 0.21 11.2 6.4 14 5.2 0.0 5.1 5 2 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II PAS_9 PF13426.7 KPA42241.1 - 2.1e-25 89.0 0.0 9.1e-18 64.4 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KPA42241.1 - 4.4e-21 75.0 0.0 1e-11 45.0 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 KPA42241.1 - 8.1e-18 64.5 1.8 1.3e-06 28.3 0.0 4.6 4 1 0 4 4 4 3 PAS fold GATA PF00320.27 KPA42241.1 - 4.6e-15 54.9 8.9 9.7e-15 53.9 8.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.6 KPA42241.1 - 6.9e-11 42.3 0.0 0.00019 21.5 0.0 3.0 2 1 1 3 3 3 2 PAS domain PAS_4 PF08448.10 KPA42241.1 - 3.8e-09 36.8 0.0 0.00018 21.7 0.0 4.0 4 0 0 4 4 4 2 PAS fold PAS_2 PF08446.11 KPA42241.1 - 1.4e-05 25.7 0.0 0.23 12.1 0.0 3.6 3 0 0 3 3 3 1 PAS fold Glyco_transf_24 PF18404.1 KPA42242.1 - 8.7e-149 494.2 2.3 1.2e-148 493.7 2.3 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KPA42242.1 - 4.3e-67 226.8 0.0 1.2e-65 222.1 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KPA42242.1 - 1.2e-56 192.1 0.1 3.7e-54 183.9 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KPA42242.1 - 2.5e-45 154.7 0.0 5.7e-45 153.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KPA42242.1 - 2.9e-42 143.8 0.1 1.9e-40 137.9 0.1 3.4 4 0 0 4 4 4 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KPA42242.1 - 5.1e-40 136.0 0.0 9.2e-40 135.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KPA42242.1 - 0.00066 19.3 0.2 0.0014 18.2 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Coatomer_WDAD PF04053.14 KPA42243.1 - 5e-146 487.2 0.0 9.8e-146 486.3 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KPA42243.1 - 4.4e-97 325.4 0.0 5.8e-97 325.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KPA42243.1 - 3e-36 122.8 15.5 2.5e-07 31.3 0.2 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA42243.1 - 1.9e-08 34.5 0.7 0.00072 19.8 0.0 5.3 3 2 4 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain IPPT PF01715.17 KPA42243.1 - 0.02 14.7 0.0 0.058 13.2 0.0 1.7 2 0 0 2 2 2 0 IPP transferase Nup160 PF11715.8 KPA42243.1 - 0.048 12.3 6.4 5.6 5.5 0.0 4.0 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.20 KPA42243.1 - 0.19 11.6 0.8 2.6 7.9 0.0 2.8 3 0 0 3 3 3 0 Region in Clathrin and VPS CSN8_PSD8_EIF3K PF10075.9 KPA42244.1 - 2.4e-19 69.7 0.0 4.6e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KPA42244.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 SAC3/GANP family Sel1 PF08238.12 KPA42245.1 - 6e-15 55.4 24.1 2.7e-05 24.7 0.2 7.2 7 1 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.28 KPA42245.1 - 0.0034 17.2 3.7 0.0059 16.4 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA42245.1 - 0.088 13.1 0.2 0.088 13.1 0.2 2.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPA42245.1 - 0.2 11.9 1.6 4.2 7.7 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPA42245.1 - 0.27 12.0 3.3 2.7 8.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 KPA42246.1 - 7.1e-15 55.1 0.0 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA42246.1 - 2.3e-07 32.0 0.0 5.5e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA42246.1 - 0.061 13.2 0.0 0.56 10.1 0.0 2.4 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain DUF3638 PF12340.8 KPA42247.1 - 8.6e-94 313.1 0.1 1.9e-93 312.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KPA42247.1 - 1.3e-15 56.5 0.1 2.9e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) LPD22 PF18834.1 KPA42247.1 - 0.0036 17.5 0.2 0.0092 16.2 0.2 1.6 1 0 0 1 1 1 1 Large polyvalent protein associated domain 22 HTH_AsnC-type PF13404.6 KPA42247.1 - 1.4 8.8 3.6 1.1 9.2 0.9 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain EI24 PF07264.11 KPA42248.1 - 8.2e-09 35.9 17.6 1.5e-08 35.1 17.6 1.4 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Exo_endo_phos PF03372.23 KPA42249.1 - 3.5e-08 33.3 0.2 1.7e-07 31.0 0.2 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Vps62 PF06101.11 KPA42250.1 - 2.2e-09 36.2 4.0 2e-08 33.0 1.7 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 DUF1539 PF07560.11 KPA42251.1 - 0.11 12.5 1.3 1.4 9.0 0.2 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) Dynamin_N PF00350.23 KPA42252.1 - 2.5e-09 37.4 2.1 5.9e-09 36.2 0.0 2.7 3 2 0 3 3 3 1 Dynamin family AAA_30 PF13604.6 KPA42252.1 - 0.025 14.3 0.0 0.077 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KPA42252.1 - 0.074 13.1 2.2 16 5.6 0.0 3.6 4 1 0 4 4 4 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KPA42252.1 - 0.74 10.3 6.2 1.1 9.8 0.0 2.9 2 1 0 2 2 2 0 ABC transporter SOGA PF11365.8 KPA42252.1 - 0.88 10.7 10.9 0.68 11.1 0.1 4.0 3 1 1 4 4 4 0 Protein SOGA DPM3 PF08285.11 KPA42253.1 - 9.5e-35 118.7 0.1 1e-34 118.5 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4355 PF14265.6 KPA42254.1 - 0.056 13.7 2.4 0.099 12.9 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) NB-ARC PF00931.22 KPA42255.1 - 2.1e-17 63.2 0.0 2.9e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KPA42255.1 - 0.00052 20.3 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KPA42255.1 - 0.00086 18.8 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein PNP_UDP_1 PF01048.20 KPA42255.1 - 0.0033 16.7 0.0 0.01 15.1 0.0 1.9 2 0 0 2 2 2 1 Phosphorylase superfamily AAA_16 PF13191.6 KPA42255.1 - 0.01 16.2 0.1 0.089 13.2 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KPA42255.1 - 0.013 15.4 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 KPA42255.1 - 0.19 11.7 0.0 0.68 9.9 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TB2_DP1_HVA22 PF03134.19 KPA42256.1 - 7.5e-26 89.9 9.4 1.2e-25 89.3 9.4 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mgm101p PF06420.12 KPA42257.1 - 1.2e-78 262.5 0.0 1.9e-78 261.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 CHCH PF06747.13 KPA42258.1 - 0.00034 20.7 7.2 0.00069 19.7 7.2 1.6 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KPA42258.1 - 0.0043 17.0 1.2 0.08 13.0 0.2 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GT-D PF08759.11 KPA42258.1 - 0.033 13.8 0.4 0.035 13.8 0.4 1.0 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Cmc1 PF08583.10 KPA42258.1 - 0.06 13.4 7.2 0.14 12.2 6.1 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like BPL_N PF09825.9 KPA42259.1 - 8.1e-147 489.2 0.0 9.8e-147 488.9 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KPA42259.1 - 6.5e-20 71.4 0.0 9.9e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MGC-24 PF05283.11 KPA42260.1 - 2.2e-06 28.1 0.2 8.1e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2207 PF09972.9 KPA42260.1 - 0.00054 18.8 0.1 0.00073 18.4 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) PFO_beta_C PF12367.8 KPA42260.1 - 0.048 13.8 0.1 0.098 12.8 0.1 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal DUF3262 PF11660.8 KPA42260.1 - 0.18 12.2 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Pam16 PF03656.13 KPA42261.1 - 6e-32 110.3 0.2 7e-32 110.1 0.2 1.0 1 0 0 1 1 1 1 Pam16 Arm PF00514.23 KPA42262.1 - 0.0016 18.4 9.3 2.8 8.1 0.1 6.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KPA42262.1 - 0.0036 17.4 1.0 6.4 7.3 0.0 4.5 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 KPA42262.1 - 0.013 15.9 3.0 9.7 6.7 0.1 4.5 4 1 0 4 4 4 0 HEAT repeats Ribosomal_L13e PF01294.18 KPA42263.1 - 7.5e-76 254.0 4.2 1e-75 253.5 4.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e COX14 PF14880.6 KPA42264.1 - 7.4e-21 73.8 0.3 1.8e-20 72.5 0.3 1.7 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DAHP_synth_1 PF00793.20 KPA42266.1 - 6.3e-105 350.0 0.1 8e-105 349.6 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_L50 PF10501.9 KPA42268.1 - 4.3e-19 68.7 0.1 1.4e-18 67.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal subunit 39S STAR_dimer PF16544.5 KPA42268.1 - 0.0084 15.7 0.0 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 Homodimerisation region of STAR domain protein Peptidase_M1 PF01433.20 KPA42269.1 - 1e-85 286.7 0.8 3.1e-85 285.2 0.3 2.0 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 KPA42269.1 - 1.1e-80 271.5 2.8 4.5e-79 266.3 0.9 2.4 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KPA42269.1 - 2.7e-51 174.4 2.1 2.7e-51 174.4 2.1 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KPA42269.1 - 0.023 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) DUF4861 PF16153.5 KPA42269.1 - 0.026 13.5 0.6 2.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4861) DUF3224 PF11528.8 KPA42269.1 - 0.12 12.2 0.1 0.36 10.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) TauD PF02668.16 KPA42270.1 - 9.8e-52 176.4 0.0 1.3e-51 175.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FYVE_2 PF02318.16 KPA42272.1 - 0.29 11.4 2.5 0.53 10.5 2.5 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger MFS_1 PF07690.16 KPA42273.1 - 6e-14 51.7 15.6 6.4e-12 45.1 15.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1304 PF06993.12 KPA42274.1 - 6.1e-45 151.7 2.0 7.2e-45 151.5 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) E1-E2_ATPase PF00122.20 KPA42275.1 - 1.4e-34 119.2 13.8 1.6e-34 119.0 2.6 4.0 4 1 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 KPA42275.1 - 1.8e-15 57.8 0.0 3.8e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPA42275.1 - 9e-12 44.5 0.0 1.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPA42275.1 - 0.0022 17.8 0.1 0.0039 17.0 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sigma_reg_N PF13800.6 KPA42275.1 - 1.7 9.0 4.0 3.2 8.1 0.1 2.9 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Zn_clus PF00172.18 KPA42279.1 - 5.4e-09 36.0 5.7 8.4e-09 35.4 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA42279.1 - 0.00076 18.6 0.1 0.0019 17.2 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain BCMA-Tall_bind PF09257.10 KPA42279.1 - 3 8.0 7.0 6.3 7.0 7.0 1.5 1 0 0 1 1 1 0 BCMA, TALL-1 binding Aldo_ket_red PF00248.21 KPA42280.1 - 3.2e-70 236.6 0.0 3.7e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Lipoprot_C PF08794.10 KPA42280.1 - 0.13 12.3 0.0 29 4.6 0.0 2.7 3 0 0 3 3 3 0 Lipoprotein GNA1870 C terminal like NmrA PF05368.13 KPA42281.1 - 6.6e-12 45.5 0.4 1.6e-11 44.2 0.4 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA42281.1 - 9.1e-11 42.0 0.9 1.4e-10 41.3 0.4 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KPA42281.1 - 3e-06 26.9 0.1 4.6e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KPA42281.1 - 0.00077 19.9 0.2 0.0013 19.2 0.2 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ApbA PF02558.16 KPA42281.1 - 0.0073 16.0 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KPA42281.1 - 0.011 16.2 0.4 0.02 15.5 0.4 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.21 KPA42281.1 - 0.019 14.7 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase KR PF08659.10 KPA42281.1 - 0.026 14.4 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 KPA42281.1 - 0.027 14.7 0.1 0.054 13.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 KPA42281.1 - 0.035 14.2 0.1 0.055 13.6 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 KPA42281.1 - 0.044 14.6 0.1 0.071 13.9 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short PF00106.25 KPA42281.1 - 0.069 12.6 2.4 4 6.8 0.1 2.2 1 1 1 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KPA42281.1 - 0.18 10.9 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Big_3_5 PF16640.5 KPA42281.1 - 0.2 11.9 1.6 19 5.5 0.0 2.7 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) PPR_2 PF13041.6 KPA42282.1 - 1.7e-46 156.2 6.0 1.3e-08 34.9 0.0 14.9 9 5 7 16 16 16 7 PPR repeat family PPR_3 PF13812.6 KPA42282.1 - 6.3e-32 109.4 0.1 0.0095 16.0 0.0 11.6 9 3 3 12 12 12 8 Pentatricopeptide repeat domain PPR PF01535.20 KPA42282.1 - 9.8e-26 88.2 29.3 0.0011 19.1 0.1 15.3 18 0 0 18 18 18 6 PPR repeat PPR_1 PF12854.7 KPA42282.1 - 9.6e-22 76.4 4.9 1.2e-06 28.1 0.0 10.0 11 0 0 11 11 11 4 PPR repeat PPR_long PF17177.4 KPA42282.1 - 1.7e-18 66.8 9.1 4.9e-07 29.3 0.0 6.6 6 1 0 6 6 6 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KPA42282.1 - 0.00012 22.5 0.0 0.004 17.5 0.0 3.3 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 KPA42282.1 - 0.0013 18.6 0.3 0.079 12.8 0.1 3.5 3 1 1 4 4 4 1 Mitochondrial ATPase expression TPR_8 PF13181.6 KPA42282.1 - 1.2 9.5 3.0 9.1 6.8 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.26 KPA42283.1 - 2.8e-15 56.3 1.7 7e-15 55.0 1.7 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KPA42283.1 - 7.1e-09 35.9 0.0 2.1e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 GHMP kinases C terminal Aldedh PF00171.22 KPA42285.1 - 3.4e-129 431.4 0.0 3.8e-129 431.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KPA42285.1 - 0.02 13.9 0.0 0.072 12.1 0.0 1.8 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) RRM_1 PF00076.22 KPA42286.1 - 2.1e-07 30.6 0.0 2.2e-05 24.2 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) N_formyltrans_C PF18216.1 KPA42286.1 - 0.045 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain CDC45 PF02724.14 KPA42286.1 - 7.7 4.7 16.1 0.22 9.8 5.0 2.0 2 0 0 2 2 2 0 CDC45-like protein NMD3 PF04981.13 KPA42287.1 - 4e-78 262.2 2.0 5.9e-78 261.7 2.0 1.3 1 0 0 1 1 1 1 NMD3 family CvfB_WH PF17783.1 KPA42287.1 - 0.18 11.7 0.5 0.39 10.6 0.5 1.5 1 0 0 1 1 1 0 CvfB-like winged helix domain DZR PF12773.7 KPA42287.1 - 6.2 6.9 8.8 2.5e+02 1.8 8.8 2.7 1 1 0 1 1 1 0 Double zinc ribbon Aminotran_1_2 PF00155.21 KPA42289.1 - 2.5e-89 300.0 0.0 2.9e-89 299.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.9 KPA42290.1 - 3e-09 37.0 1.1 1.5e-08 34.7 0.1 2.6 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KPA42290.1 - 0.017 15.1 0.3 0.17 11.9 0.0 2.8 3 0 0 3 3 3 0 SNARE domain ST7 PF04184.12 KPA42290.1 - 0.081 11.4 0.2 0.11 11.0 0.2 1.3 1 0 0 1 1 1 0 ST7 protein MFS_1 PF07690.16 KPA42291.1 - 3.3e-53 180.9 22.8 3.3e-53 180.9 22.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA42291.1 - 9.4e-07 28.0 6.2 9.4e-07 28.0 6.2 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KPA42291.1 - 0.058 11.7 2.0 0.093 11.0 2.0 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1077 PF06417.12 KPA42292.1 - 1.6e-48 163.6 6.2 2e-48 163.3 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.20 KPA42293.1 - 2e-122 409.4 7.5 2.6e-122 409.1 7.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KPA42293.1 - 3.6e-55 186.4 7.8 1e-54 185.0 0.1 3.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KPA42293.1 - 2.9e-14 53.2 4.9 0.00034 20.9 0.0 5.1 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 KPA42293.1 - 4.4e-11 42.0 1.7 0.0015 18.6 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KPA42293.1 - 0.00021 21.7 1.5 23 5.6 0.1 6.0 6 0 0 6 6 6 0 HEAT-like repeat Atx10homo_assoc PF09759.9 KPA42293.1 - 0.0007 19.6 0.2 2.2 8.4 0.0 4.6 4 1 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.8 KPA42293.1 - 0.002 17.7 1.4 0.52 9.8 0.0 2.9 3 0 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 KPA42293.1 - 0.0088 16.2 0.8 0.98 9.6 0.0 3.4 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KPA42293.1 - 0.15 12.1 2.8 14 5.8 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 KPA42293.1 - 0.2 11.4 1.0 20 4.9 0.1 2.8 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) MFS_1 PF07690.16 KPA42294.1 - 3.8e-21 75.4 17.6 3.8e-21 75.4 17.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 KPA42296.1 - 3.2e-08 33.6 6.5 5e-08 32.9 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDZ_assoc PF10600.9 KPA42297.1 - 0.027 15.3 2.5 6.9 7.6 0.0 3.2 3 1 0 3 3 3 0 PDZ-associated domain of NMDA receptors Aminotran_3 PF00202.21 KPA42298.1 - 5.2e-117 390.9 0.0 5.8e-117 390.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DNA_ligase_IV PF11411.8 KPA42298.1 - 0.0066 16.5 0.5 0.012 15.7 0.5 1.4 1 0 0 1 1 1 1 DNA ligase IV Aldedh PF00171.22 KPA42299.1 - 7.9e-165 548.8 0.1 8.9e-165 548.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPA42299.1 - 2.3e-06 27.2 0.2 0.046 13.2 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) DUF126 PF01989.16 KPA42299.1 - 0.24 11.2 1.0 0.61 9.9 0.6 1.9 1 1 0 1 1 1 0 Aconitase X swivel domain TPR_16 PF13432.6 KPA42299.1 - 1.7 9.3 6.6 0.34 11.6 2.7 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KPA42301.1 - 3.8e-20 72.0 0.0 7.1e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA42301.1 - 5.2e-07 29.7 10.6 1e-06 28.7 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1682 PF07946.14 KPA42302.1 - 8.3e-108 360.4 0.2 9.6e-108 360.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4407 PF14362.6 KPA42302.1 - 5.9 6.2 10.1 8.5 5.6 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Haspin_kinase PF12330.8 KPA42303.1 - 1.2e-33 116.5 0.0 1.7e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DDRGK PF09756.9 KPA42304.1 - 0.032 13.8 19.3 0.05 13.2 19.3 1.5 1 0 0 1 1 1 0 DDRGK domain Pex26 PF07163.12 KPA42304.1 - 0.064 12.6 13.2 0.012 15.0 8.6 2.1 2 1 0 2 2 2 0 Pex26 protein CDC45 PF02724.14 KPA42304.1 - 0.095 11.0 16.0 0.13 10.6 16.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 KPA42304.1 - 0.1 11.2 23.4 0.14 10.7 23.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4407 PF14362.6 KPA42304.1 - 0.23 10.8 9.3 0.36 10.1 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EMC3_TMCO1 PF01956.16 KPA42304.1 - 0.65 9.7 2.1 1 9.1 2.1 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF572 PF04502.13 KPA42304.1 - 0.93 9.0 22.2 1.4 8.5 22.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) V_ATPase_I PF01496.19 KPA42304.1 - 1.6 6.6 4.3 1.9 6.3 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 KPA42304.1 - 3.6 8.1 29.2 6.7 7.3 29.2 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region ALMT PF11744.8 KPA42304.1 - 3.7 6.3 10.4 5.1 5.8 10.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter GREB1 PF15782.5 KPA42304.1 - 6.3 3.8 8.8 9.5 3.2 8.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 KPA42304.1 - 9.2 4.6 10.2 13 4.1 10.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 Neur_chan_memb PF02932.16 KPA42304.1 - 9.8 6.2 8.5 21 5.1 8.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PHF5 PF03660.14 KPA42305.1 - 4e-52 174.8 10.4 4.6e-52 174.6 10.4 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KPA42305.1 - 0.69 7.7 7.8 0.71 7.7 7.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KPA42305.1 - 2.5 8.2 15.6 5.6 7.1 1.9 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.13 KPA42306.1 - 1.4e-33 115.7 12.1 1.4e-33 115.7 12.1 2.5 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 KPA42306.1 - 6.2e-05 23.2 8.2 6.2e-05 23.2 8.2 3.8 2 2 1 3 3 3 1 RNSP1-SAP18 binding (RSB) motif Abhydrolase_1 PF00561.20 KPA42307.1 - 4.2e-21 75.8 0.1 5.5e-20 72.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA42307.1 - 7.2e-13 49.7 0.0 9.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA42307.1 - 2.3e-07 30.3 0.0 5.9e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KPA42307.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PhoLip_ATPase_C PF16212.5 KPA42308.1 - 2.4e-80 269.9 19.9 2.4e-80 269.9 19.9 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KPA42308.1 - 5.6e-27 93.2 8.0 1.6e-26 91.7 8.0 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KPA42308.1 - 5.7e-12 45.6 0.0 4.6e-11 42.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPA42308.1 - 5e-11 43.3 0.5 6.7e-05 23.3 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KPA42308.1 - 6.3e-08 32.3 0.0 1.6e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KPA42308.1 - 0.004 16.9 0.4 0.013 15.2 0.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3084 PF11283.8 KPA42308.1 - 0.079 13.0 0.2 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) Mt_ATP-synt_B PF05405.14 KPA42308.1 - 0.16 11.6 0.5 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ecl1 PF12855.7 KPA42309.1 - 3.7e-38 132.4 15.1 3.7e-38 132.4 15.1 1.9 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-FLZ PF04570.14 KPA42309.1 - 0.0012 18.3 2.2 0.0023 17.4 2.2 1.4 1 0 0 1 1 1 1 zinc-finger of the FCS-type, C2-C2 DUF823 PF05689.11 KPA42309.1 - 0.12 12.2 0.2 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) PLATZ PF04640.14 KPA42309.1 - 0.16 12.6 0.6 0.27 11.9 0.6 1.3 1 0 0 1 1 1 0 PLATZ transcription factor DUF2256 PF10013.9 KPA42309.1 - 0.32 11.1 6.0 2.7 8.2 6.0 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Kelch_5 PF13854.6 KPA42310.1 - 8e-16 57.6 11.6 2.8e-11 43.2 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 KPA42310.1 - 2e-08 34.2 13.0 0.021 15.1 0.2 5.8 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KPA42310.1 - 8.2e-06 25.7 12.3 0.021 14.9 0.1 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain SKG6 PF08693.10 KPA42310.1 - 0.00021 20.7 0.9 0.00041 19.7 0.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_3 PF13415.6 KPA42310.1 - 0.0021 18.3 14.8 0.067 13.5 0.8 5.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Rax2 PF12768.7 KPA42310.1 - 0.029 13.8 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Mid2 PF04478.12 KPA42310.1 - 0.046 13.6 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 KPA42310.1 - 0.052 14.4 0.0 0.094 13.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PIRT PF15099.6 KPA42310.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Kelch_2 PF07646.15 KPA42310.1 - 0.4 10.7 13.9 2.5 8.2 0.4 5.5 5 1 0 5 5 5 0 Kelch motif Kelch_1 PF01344.25 KPA42310.1 - 1.1 9.0 11.2 0.18 11.4 0.4 4.3 5 0 0 5 5 5 0 Kelch motif Clathrin_H_link PF13838.6 KPA42311.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Clathrin-H-link SYF2 PF08231.12 KPA42312.1 - 6.8e-55 185.8 16.8 6.8e-55 185.8 16.8 1.8 2 0 0 2 2 2 1 SYF2 splicing factor Adenylsucc_synt PF00709.21 KPA42312.1 - 0.052 12.5 2.3 0.096 11.6 0.2 2.0 1 1 1 2 2 2 0 Adenylosuccinate synthetase DsbG_N PF18257.1 KPA42312.1 - 0.056 13.6 0.9 0.15 12.2 0.1 2.2 2 1 0 2 2 2 0 Disulfide isomerase DsbG N-terminal NAD_binding_10 PF13460.6 KPA42313.1 - 1.3e-06 28.5 0.0 1.2e-05 25.3 0.0 2.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA42313.1 - 1.8e-05 24.3 0.0 3.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA42313.1 - 0.0014 17.6 0.0 0.0034 16.4 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPA42313.1 - 0.0034 16.6 0.1 0.21 10.7 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KPA42313.1 - 0.034 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase YEATS PF03366.16 KPA42314.1 - 1.1e-28 99.1 0.1 1.8e-28 98.3 0.1 1.4 1 0 0 1 1 1 1 YEATS family XkdW PF09636.10 KPA42314.1 - 0.0086 16.2 0.2 0.018 15.2 0.2 1.5 1 0 0 1 1 1 1 XkdW protein TnpV PF14198.6 KPA42314.1 - 0.015 15.3 0.9 0.028 14.4 0.9 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV ER-remodelling PF14755.6 KPA42315.1 - 0.41 10.9 5.7 0.093 13.0 1.8 1.8 2 0 0 2 2 2 0 Intracellular membrane remodeller Ins_P5_2-kin PF06090.12 KPA42316.1 - 6.4e-35 121.1 0.0 3.5e-34 118.7 0.0 1.9 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Nucleoside_tran PF01733.18 KPA42317.1 - 3.9e-39 134.8 11.7 4.3e-39 134.7 8.7 2.3 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 KPA42317.1 - 3.5e-06 26.2 36.7 0.011 14.6 6.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily UL45 PF05473.12 KPA42317.1 - 0.066 12.8 0.3 0.13 11.9 0.2 1.5 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Catalase PF00199.19 KPA42318.1 - 2.5e-161 537.1 0.1 3.1e-161 536.8 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KPA42318.1 - 1.1e-46 158.3 0.6 1.7e-46 157.7 0.6 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KPA42318.1 - 3e-17 62.6 0.0 5.5e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive HET PF06985.11 KPA42319.1 - 6e-17 62.4 0.4 6e-17 62.4 0.4 3.3 2 2 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF3535 PF12054.8 KPA42320.1 - 3.9e-127 425.1 0.2 4.5e-126 421.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KPA42320.1 - 7.5e-66 222.2 0.0 1.8e-65 221.0 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA42320.1 - 2.9e-19 69.4 0.0 1.2e-18 67.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KPA42320.1 - 2.4e-18 64.6 0.6 0.0076 16.4 0.0 8.1 7 0 0 7 7 7 4 HEAT repeat Vac14_Fab1_bd PF12755.7 KPA42320.1 - 4e-09 36.9 0.7 0.23 12.1 0.0 3.9 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KPA42320.1 - 7.6e-09 35.8 0.6 0.00056 20.2 0.1 5.8 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 KPA42320.1 - 3.7e-05 24.1 6.9 8.2 7.1 0.0 7.7 9 0 0 9 9 8 1 HEAT-like repeat CLASP_N PF12348.8 KPA42320.1 - 0.0026 17.4 0.4 2.1 7.9 0.3 3.0 2 1 0 2 2 2 2 CLASP N terminal zf-C2H2_assoc PF16606.5 KPA42320.1 - 0.022 15.0 0.7 2.3 8.5 0.0 2.6 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers UME PF08064.13 KPA42320.1 - 0.032 14.2 4.9 9.1 6.3 1.0 4.1 3 1 1 4 4 4 0 UME (NUC010) domain Adaptin_N PF01602.20 KPA42320.1 - 0.035 12.7 2.5 1.1 7.7 0.2 3.4 4 0 0 4 4 4 0 Adaptin N terminal region ERCC3_RAD25_C PF16203.5 KPA42320.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SMC_N PF02463.19 KPA42321.1 - 1e-56 191.8 31.4 6.4e-56 189.2 31.4 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KPA42321.1 - 2.8e-27 95.3 0.0 1.9e-26 92.7 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 KPA42321.1 - 6.6e-16 59.0 44.6 9.6e-14 51.9 13.0 4.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KPA42321.1 - 3.4e-13 50.1 13.4 3.8e-07 30.2 0.0 4.3 4 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KPA42321.1 - 1.3e-07 32.4 44.1 1.3e-07 32.4 44.1 6.9 2 2 2 4 4 1 1 AAA domain GAS PF13851.6 KPA42321.1 - 0.00029 20.2 10.4 0.00029 20.2 10.4 8.1 3 2 3 7 7 6 4 Growth-arrest specific micro-tubule binding SbcCD_C PF13558.6 KPA42321.1 - 0.00096 19.3 0.1 0.0044 17.2 0.1 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KPA42321.1 - 0.0036 17.0 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Abi_C PF14355.6 KPA42321.1 - 0.0054 16.8 1.1 0.11 12.7 0.2 3.8 3 0 0 3 3 3 1 Abortive infection C-terminus BRE1 PF08647.11 KPA42321.1 - 0.0092 16.0 10.4 0.0092 16.0 10.4 8.4 6 3 2 8 8 8 2 BRE1 E3 ubiquitin ligase ABC_tran PF00005.27 KPA42321.1 - 0.21 12.1 0.0 0.21 12.1 0.0 6.6 3 2 1 4 4 2 0 ABC transporter Matrilin_ccoil PF10393.9 KPA42321.1 - 0.41 10.5 5.1 0.67 9.9 1.8 3.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin MRP-L46 PF11788.8 KPA42322.1 - 3.4e-28 98.8 0.1 7.5e-28 97.7 0.0 1.6 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 zf-rbx1 PF12678.7 KPA42323.1 - 1.3e-10 41.4 8.7 5e-07 29.9 0.3 3.4 3 0 0 3 3 3 2 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KPA42323.1 - 4.2e-09 36.6 17.3 2.5e-07 30.9 0.3 3.6 3 1 0 3 3 3 2 Ring finger domain PHD PF00628.29 KPA42323.1 - 9.4e-09 35.0 6.4 9.4e-09 35.0 6.4 2.6 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KPA42323.1 - 1.4e-06 27.7 2.0 1.4e-06 27.7 2.0 2.2 2 0 0 2 2 2 1 PHD-finger zf-C3HC4 PF00097.25 KPA42323.1 - 4.4e-05 23.3 0.3 4.4e-05 23.3 0.3 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPA42323.1 - 0.0012 18.7 3.2 0.0012 18.7 3.2 2.8 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KPA42323.1 - 0.0016 18.3 0.7 0.0016 18.3 0.7 3.7 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KPA42323.1 - 0.0024 17.8 1.7 0.0024 17.8 1.7 2.6 3 0 0 3 3 2 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 KPA42323.1 - 0.0054 16.8 9.9 0.046 13.8 0.7 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KPA42323.1 - 0.0062 16.5 4.2 0.0062 16.5 4.2 3.6 4 0 0 4 4 4 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KPA42323.1 - 0.0085 15.7 4.2 0.0085 15.7 4.2 2.7 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KPA42323.1 - 0.015 15.2 2.6 0.015 15.2 2.6 3.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.6 KPA42323.1 - 0.064 12.9 4.1 0.041 13.5 1.0 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 KPA42323.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.0 2 0 0 2 2 1 0 PHD-like zinc-binding domain DUF282 PF03380.14 KPA42323.1 - 0.39 10.7 2.7 0.99 9.4 2.7 1.7 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 PHD_3 PF13922.6 KPA42323.1 - 0.52 10.7 2.9 2.8 8.4 0.2 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx zf-RING_9 PF13901.6 KPA42323.1 - 0.82 9.6 10.9 1 9.3 2.7 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Olduvai PF06758.13 KPA42323.1 - 1.7 9.0 5.5 1.6 9.1 0.4 3.0 2 0 0 2 2 2 0 Olduvai domain zf-RING-like PF08746.11 KPA42323.1 - 3.9 7.8 12.2 1.5 9.2 2.3 2.5 2 0 0 2 2 2 0 RING-like domain RINGv PF12906.7 KPA42323.1 - 6.4 7.0 10.2 0.43 10.7 2.1 2.6 2 0 0 2 2 2 0 RING-variant domain zf-RRN7 PF11781.8 KPA42323.1 - 9.2 6.0 10.1 12 5.7 0.6 3.2 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ribosomal_L37ae PF01780.19 KPA42324.1 - 1.5e-40 137.2 10.6 1.7e-40 137.0 10.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KPA42324.1 - 0.0024 18.0 1.6 0.0034 17.5 1.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KPA42324.1 - 0.0041 17.1 2.2 0.0069 16.3 2.2 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Sgf11 PF08209.11 KPA42324.1 - 0.0069 15.9 0.5 0.055 13.0 0.0 2.2 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) DUF1451 PF07295.11 KPA42324.1 - 0.02 14.9 1.0 0.028 14.5 1.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn-ribbon_8 PF09723.10 KPA42324.1 - 0.05 13.7 0.5 0.097 12.8 0.5 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2HC5 PF06221.13 KPA42324.1 - 0.051 13.6 0.3 0.074 13.1 0.3 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-H2C2_2 PF13465.6 KPA42324.1 - 0.093 13.2 1.4 0.49 10.9 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.15 KPA42324.1 - 0.89 9.6 4.9 0.66 10.0 0.4 2.1 1 1 1 2 2 2 0 BED zinc finger Sacchrp_dh_NADP PF03435.18 KPA42325.1 - 3.7e-10 40.2 0.1 6e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Peptidase_C2 PF00648.21 KPA42327.1 - 1.7e-29 102.8 0.0 2.7e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KPA42327.1 - 4.9e-06 26.9 0.0 0.00064 20.0 0.0 2.8 2 1 0 2 2 2 1 Calpain large subunit, domain III Mito_carr PF00153.27 KPA42328.1 - 3e-54 180.9 0.3 5.6e-20 71.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SAM_2 PF07647.17 KPA42329.1 - 4.8e-09 36.2 0.1 8.3e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KPA42329.1 - 0.00014 22.2 0.2 0.00029 21.2 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KPA42329.1 - 0.028 14.5 0.2 0.075 13.1 0.2 1.7 2 0 0 2 2 2 0 IGR protein motif DUF4508 PF14969.6 KPA42329.1 - 0.15 12.3 0.1 0.37 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) TPR_1 PF00515.28 KPA42330.1 - 2.6e-10 39.7 20.7 0.00089 19.0 2.6 9.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPA42330.1 - 1.6e-09 37.2 29.9 0.53 10.5 2.3 10.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 KPA42330.1 - 3.4e-09 36.2 15.1 0.0065 16.1 0.0 6.8 7 1 1 8 8 8 4 TPR repeat TPR_16 PF13432.6 KPA42330.1 - 3.4e-09 37.2 29.4 0.00011 22.8 0.2 8.1 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_20 PF14561.6 KPA42330.1 - 5.1e-07 29.9 10.1 0.27 11.6 2.1 6.4 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPA42330.1 - 9.1e-07 28.8 12.2 1.8 9.1 0.1 8.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA42330.1 - 3.2e-06 26.9 19.6 0.033 14.4 0.1 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPA42330.1 - 1.6e-05 24.6 11.6 0.018 15.1 0.1 7.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPA42330.1 - 6e-05 23.5 37.5 0.015 16.1 0.2 11.1 10 2 2 12 12 11 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPA42330.1 - 0.00056 20.4 25.6 0.16 12.5 0.0 8.2 7 2 3 10 10 10 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KPA42330.1 - 0.0013 19.2 0.4 0.7 10.3 0.0 3.1 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_12 PF13424.6 KPA42330.1 - 0.012 15.9 36.0 0.11 12.8 6.7 8.0 9 1 2 11 11 9 0 Tetratricopeptide repeat TPR_9 PF13371.6 KPA42330.1 - 0.012 15.7 10.9 0.72 10.0 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Aldedh PF00171.22 KPA42331.1 - 8.9e-150 499.2 0.4 1e-149 499.0 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 KPA42332.1 - 2.3e-55 188.1 0.0 3.3e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA42332.1 - 4.6e-38 131.0 0.0 7.7e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPA42332.1 - 2.2e-07 30.3 0.1 0.0022 17.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KPA42332.1 - 6.1e-05 22.2 0.0 9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KPA42332.1 - 0.00033 20.8 0.1 0.00086 19.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA42332.1 - 0.0015 17.8 0.0 0.028 13.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA42332.1 - 0.015 14.9 2.9 0.09 12.3 0.2 2.7 3 1 0 3 3 3 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KPA42332.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KPA42332.1 - 0.23 12.1 0.4 1.2 9.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1479 PF07350.12 KPA42333.1 - 1.4e-146 488.5 0.0 1.8e-146 488.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) OEP PF02321.18 KPA42333.1 - 7.1 6.4 9.4 0.29 10.9 2.6 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein AMP-binding PF00501.28 KPA42334.1 - 1.1e-231 768.8 0.0 1.7e-77 260.9 0.0 3.5 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KPA42334.1 - 2.2e-176 587.0 0.0 2.4e-30 105.6 0.0 7.2 6 2 0 6 6 6 6 Condensation domain PP-binding PF00550.25 KPA42334.1 - 1.8e-53 178.7 14.8 1.8e-09 37.8 0.2 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KPA42334.1 - 1.8e-08 35.2 0.1 7.6e-05 23.6 0.0 3.8 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 KPA42334.1 - 5.1e-06 26.4 0.0 2.2 7.9 0.0 4.9 5 0 0 5 5 5 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.15 KPA42334.1 - 8.9e-05 21.3 0.1 2.6 6.6 0.0 5.4 6 0 0 6 6 6 1 Transferase family Imm1 PF14430.6 KPA42334.1 - 0.092 13.4 1.1 28 5.4 0.1 3.2 3 0 0 3 3 3 0 Immunity protein Imm1 K_oxygenase PF13434.6 KPA42335.1 - 4.8e-105 351.5 0.0 5.7e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPA42335.1 - 1.2e-05 24.7 0.0 3.9e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA42335.1 - 3.7e-05 23.1 0.0 0.00023 20.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KPA42336.1 - 3.7e-10 39.3 0.0 9.8e-10 37.9 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA42336.1 - 8.8e-07 28.9 8.8 1.6e-06 28.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPA42337.1 - 2.6e-33 115.4 16.1 2.6e-33 115.4 16.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily RPAP1_N PF08621.10 KPA42337.1 - 0.18 11.6 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal 2TM PF13239.6 KPA42337.1 - 4.7 7.6 5.5 6.5 7.1 0.9 3.1 3 0 0 3 3 3 0 2TM domain FF PF01846.19 KPA42338.1 - 2.2e-09 37.4 6.7 8.7e-09 35.4 0.7 3.3 2 0 0 2 2 2 1 FF domain WW PF00397.26 KPA42338.1 - 6.1e-09 35.8 4.6 6.1e-09 35.8 4.6 2.2 2 0 0 2 2 2 1 WW domain DUF5641 PF18701.1 KPA42338.1 - 0.022 14.9 0.9 0.058 13.6 0.9 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5641) PAP2 PF01569.21 KPA42339.1 - 1.3e-27 96.2 0.4 1.3e-27 96.2 0.4 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KPA42339.1 - 0.0024 17.6 6.1 0.013 15.2 4.7 2.4 1 1 0 1 1 1 1 PAP2 superfamily SdpI PF13630.6 KPA42339.1 - 0.032 14.3 0.5 0.13 12.5 0.0 2.2 2 1 0 2 2 2 0 SdpI/YhfL protein family RseC_MucC PF04246.12 KPA42339.1 - 0.23 11.4 2.1 3.2 7.7 0.3 2.7 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Proteasome PF00227.26 KPA42340.1 - 1.7e-60 203.8 0.1 2e-60 203.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KPA42340.1 - 2.7e-13 49.3 0.1 8.7e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 KPA42340.1 - 0.013 15.6 0.4 0.04 14.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 KPA42340.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SPOC PF07744.13 KPA42341.1 - 2.5e-25 89.1 0.0 5.4e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KPA42341.1 - 7.3e-19 68.3 2.1 7.3e-19 68.3 2.1 2.4 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KPA42341.1 - 7e-09 35.5 9.1 1.4e-08 34.5 9.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KPA42341.1 - 0.063 13.7 1.6 0.18 12.2 1.6 1.8 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx GSDH PF07995.11 KPA42341.1 - 0.12 11.7 0.7 5.3 6.3 0.0 2.8 3 0 0 3 3 3 0 Glucose / Sorbosone dehydrogenase SnoaL PF07366.12 KPA42342.1 - 1.6e-08 34.4 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KPA42342.1 - 5.5e-05 23.7 0.0 7.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Med7 PF05983.11 KPA42344.1 - 7.1e-61 205.6 0.3 9.1e-61 205.3 0.3 1.1 1 0 0 1 1 1 1 MED7 protein TBCC_N PF16752.5 KPA42344.1 - 0.14 12.7 3.2 0.18 12.2 0.7 2.3 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain zf-C2H2_jaz PF12171.8 KPA42345.1 - 0.0004 20.6 0.0 0.00068 19.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF641 PF04859.12 KPA42345.1 - 0.03 14.7 3.5 0.065 13.6 3.5 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-met PF12874.7 KPA42345.1 - 0.089 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type FAM76 PF16046.5 KPA42345.1 - 2.6 7.3 12.8 4.7e+02 -0.1 12.8 2.1 1 1 0 1 1 1 0 FAM76 protein F-box PF00646.33 KPA42346.1 - 1.3e-07 31.3 0.2 1.3e-07 31.3 0.2 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KPA42346.1 - 1e-06 28.5 1.2 2.6e-06 27.2 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KPA42346.1 - 7.9e-06 25.8 0.1 7.9e-06 25.8 0.1 2.3 2 0 0 2 2 2 1 F-box PelD_GGDEF PF16963.5 KPA42348.1 - 0.11 12.3 0.3 0.14 12.0 0.3 1.2 1 0 0 1 1 1 0 PelD GGDEF domain LAMTOR PF15454.6 KPA42349.1 - 2e-08 34.7 0.1 3.3e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Sugar_tr PF00083.24 KPA42352.1 - 1.1e-81 275.1 15.0 1.3e-81 274.8 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA42352.1 - 1.1e-29 103.4 14.7 1.8e-29 102.8 14.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA42352.1 - 5.9e-06 25.0 1.1 1.2e-05 24.0 1.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KPA42352.1 - 1.6e-05 23.7 0.4 1.6e-05 23.7 0.4 2.8 3 1 1 4 4 4 1 MFS/sugar transport protein OATP PF03137.20 KPA42352.1 - 0.0012 17.2 1.3 0.0012 17.2 1.3 3.0 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family PTR2 PF00854.21 KPA42352.1 - 0.056 12.3 4.3 0.018 13.9 1.4 1.6 2 0 0 2 2 2 0 POT family Dynamin_N PF00350.23 KPA42353.1 - 2.5e-20 73.2 0.0 2.7e-19 69.9 0.0 2.2 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KPA42353.1 - 7e-12 45.2 0.1 5.3e-05 22.6 0.0 2.5 3 0 0 3 3 3 2 Dynamin central region GED PF02212.18 KPA42353.1 - 0.00066 19.8 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KPA42353.1 - 0.024 14.7 0.0 0.15 12.2 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase Amidase02_C PF12123.8 KPA42353.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DLP_helical PF18709.1 KPA42353.1 - 0.19 10.9 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Dynamin-like helical domain Fungal_trans PF04082.18 KPA42354.1 - 2e-19 69.7 0.0 3.4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA42354.1 - 5.9e-09 35.9 11.7 1e-08 35.2 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_3 PF08447.12 KPA42356.1 - 3.1e-12 46.6 0.0 3.2e-10 40.2 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KPA42356.1 - 1.3e-09 38.0 0.0 2.8e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KPA42356.1 - 2.2e-06 27.9 0.0 0.00051 20.3 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KPA42356.1 - 8.5e-05 22.8 0.0 0.0095 16.2 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KPA42356.1 - 0.0024 18.0 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 PAS domain Med13_C PF06333.12 KPA42356.1 - 0.12 11.6 0.0 0.12 11.6 0.0 3.0 3 0 0 3 3 3 0 Mediator complex subunit 13 C-terminal domain Yip1 PF04893.17 KPA42357.1 - 1e-11 44.8 14.7 1.4e-11 44.4 14.7 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KPA42357.1 - 0.12 12.1 7.3 0.18 11.6 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Ran_BP1 PF00638.18 KPA42358.1 - 1.6e-12 47.8 1.4 4.5e-05 23.7 0.0 2.6 3 0 0 3 3 3 2 RanBP1 domain DEAD PF00270.29 KPA42359.1 - 5.2e-28 98.0 0.0 9.4e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KPA42359.1 - 4e-23 82.0 0.3 9.6e-23 80.7 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KPA42359.1 - 1.4e-11 44.7 0.0 1.6e-10 41.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA42359.1 - 5e-08 33.1 0.0 9.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KPA42359.1 - 0.0091 16.3 0.2 0.019 15.2 0.2 1.6 1 1 0 1 1 1 1 DNA replication factor CDT1 like Na_Ca_ex PF01699.24 KPA42360.1 - 2.7e-23 82.6 31.8 1.1e-13 51.4 11.7 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1298 PF06974.13 KPA42360.1 - 0.026 14.5 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) DUF4500 PF14937.6 KPA42360.1 - 0.065 13.3 1.7 1 9.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4500) MIG-14_Wnt-bd PF06664.12 KPA42360.1 - 0.15 11.3 13.0 0.02 14.1 5.1 2.2 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Oxidored_q4 PF00507.19 KPA42360.1 - 9.1 6.5 10.4 14 5.9 1.1 3.2 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Mo-co_dimer PF03404.16 KPA42361.1 - 2.8e-63 212.0 0.4 5.1e-63 211.2 0.4 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KPA42361.1 - 1.1e-55 187.9 0.0 1.9e-55 187.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KPA42361.1 - 1e-33 115.6 0.0 1.9e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KPA42361.1 - 9.8e-31 106.6 0.0 3.8e-30 104.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KPA42361.1 - 2.6e-21 75.6 0.0 4.9e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KPA42361.1 - 0.011 15.9 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 Ferric reductase NAD binding domain MIF4G PF02854.19 KPA42362.1 - 1.2e-55 188.5 0.0 9.9e-29 100.5 0.0 3.8 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KPA42362.1 - 3.8e-42 144.2 6.8 3.8e-42 144.2 6.8 3.0 4 0 0 4 4 4 1 Up-frameshift suppressor 2 RseA_C PF03873.13 KPA42362.1 - 0.07 13.4 1.7 0.21 11.9 1.7 1.8 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain CBP4 PF07960.11 KPA42362.1 - 0.29 11.0 0.0 0.29 11.0 0.0 2.7 3 0 0 3 3 3 0 CBP4 Fib_alpha PF08702.10 KPA42362.1 - 0.73 10.0 3.6 0.37 11.0 0.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Chitin_synth_2 PF03142.15 KPA42363.1 - 8.3e-23 80.8 3.6 8.3e-23 80.8 3.6 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KPA42363.1 - 3.4e-15 56.5 4.1 3.4e-15 56.5 4.1 2.8 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KPA42363.1 - 6.8e-12 45.8 0.2 2.9e-11 43.7 0.0 2.0 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPA42363.1 - 0.0043 16.9 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 HSP70 PF00012.20 KPA42364.1 - 1.2e-164 548.8 0.9 1.2e-164 548.8 0.9 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KPA42364.1 - 3.1e-13 49.2 0.0 7.6e-12 44.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KPA42364.1 - 0.0088 16.4 5.8 0.17 12.3 0.1 3.2 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 KPA42364.1 - 0.043 13.3 0.0 0.4 10.1 0.0 2.3 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family GTP_EFTU PF00009.27 KPA42365.1 - 1.5e-34 119.3 0.0 1.5e-34 119.3 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KPA42365.1 - 3.4e-20 72.1 0.0 9.4e-20 70.7 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KPA42365.1 - 5.9e-08 33.0 9.2 1.6e-07 31.6 0.1 3.9 4 0 0 4 4 4 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KPA42365.1 - 1.1e-07 31.9 0.1 9.6e-06 25.7 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KPA42365.1 - 6.2e-07 29.2 0.1 3.1e-06 27.0 0.1 2.3 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 KPA42365.1 - 0.0001 22.5 0.0 0.00028 21.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KPA42365.1 - 0.0013 18.6 0.1 0.0082 16.0 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMS1_N PF10433.9 KPA42366.1 - 5.6e-64 216.5 0.0 4.9e-63 213.5 0.0 2.3 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RabGAP-TBC PF00566.18 KPA42367.1 - 3.3e-22 79.2 0.0 4.7e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Vps52 PF04129.12 KPA42368.1 - 2.6e-125 419.1 2.3 3.5e-125 418.6 2.3 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KPA42368.1 - 0.002 16.6 2.7 0.0059 15.1 2.7 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec3 DUF812 PF05667.11 KPA42368.1 - 0.0026 16.7 1.2 0.0039 16.1 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Exo70 PF03081.15 KPA42368.1 - 0.0029 16.7 0.0 0.014 14.5 0.0 2.1 2 0 0 2 2 2 1 Exo70 exocyst complex subunit DUF4795 PF16043.5 KPA42368.1 - 0.021 14.4 4.6 0.045 13.3 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) CCDC144C PF14915.6 KPA42368.1 - 0.024 13.8 3.8 0.05 12.7 3.8 1.5 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Spc7 PF08317.11 KPA42368.1 - 0.043 12.7 4.1 0.079 11.8 4.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Apolipoprotein PF01442.18 KPA42368.1 - 0.047 13.6 4.9 0.047 13.6 2.4 2.1 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Med10 PF09748.9 KPA42368.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex DUF1664 PF07889.12 KPA42368.1 - 0.16 12.0 0.5 0.44 10.6 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 KPA42368.1 - 0.28 11.5 2.9 1.8 8.8 0.4 3.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 KPA42368.1 - 6 6.9 9.2 0.46 10.5 2.1 2.7 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 eIF-5a PF01287.20 KPA42369.1 - 1.7e-28 98.5 0.9 2.3e-28 98.1 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KPA42369.1 - 0.00034 20.6 0.5 0.0006 19.8 0.0 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain ubiquitin PF00240.23 KPA42370.1 - 6.6e-33 112.3 0.6 1.1e-32 111.6 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KPA42370.1 - 1.9e-30 104.5 10.1 4e-30 103.5 10.1 1.6 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KPA42370.1 - 3.7e-15 55.5 0.7 6.6e-15 54.7 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-RRN7 PF11781.8 KPA42370.1 - 1.6e-10 40.5 2.0 1.6e-10 40.5 2.0 2.3 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ubiquitin_2 PF14560.6 KPA42370.1 - 0.00021 21.7 0.2 0.00054 20.4 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KPA42370.1 - 0.037 14.4 0.1 0.091 13.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 KPA42370.1 - 0.041 13.8 0.1 0.081 12.9 0.1 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KPA42370.1 - 0.19 11.9 1.5 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DZR PF12773.7 KPA42370.1 - 1.8 8.7 6.1 20 5.3 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon Yip1 PF04893.17 KPA42371.1 - 5.1e-12 45.8 15.1 5.1e-12 45.8 15.1 1.5 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 KPA42371.1 - 0.3 10.6 4.7 0.69 9.4 3.5 2.0 2 1 0 2 2 2 0 YIF1 Rhodanese PF00581.20 KPA42372.1 - 8.4e-18 64.9 0.0 1.2e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain RlmM_FDX PF18125.1 KPA42372.1 - 0.15 12.5 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 RlmM ferredoxin-like domain p450 PF00067.22 KPA42373.1 - 5.6e-47 160.5 0.0 8.6e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Inhibitor_I9 PF05922.16 KPA42374.1 - 2.4e-11 44.1 0.2 4e-11 43.4 0.2 1.3 1 1 0 1 1 1 1 Peptidase inhibitor I9 AMP-binding PF00501.28 KPA42375.1 - 0 1487.7 5.5 5.5e-77 259.1 0.3 6.3 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 KPA42375.1 - 0 1262.2 0.0 6.9e-58 196.4 0.0 14.1 12 3 1 13 13 13 12 Condensation domain PP-binding PF00550.25 KPA42375.1 - 2.4e-87 287.3 8.0 2.1e-13 50.4 0.0 7.9 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KPA42375.1 - 2.7e-14 53.9 0.0 0.24 12.4 0.0 7.1 6 0 0 6 6 6 3 AMP-binding enzyme C-terminal domain OAD_beta PF03977.13 KPA42375.1 - 0.042 12.8 4.2 1.9 7.4 0.0 4.2 5 0 0 5 5 5 0 Na+-transporting oxaloacetate decarboxylase beta subunit Transferase PF02458.15 KPA42375.1 - 0.054 12.1 0.0 24 3.4 0.0 3.9 4 0 0 4 4 4 0 Transferase family DUF1798 PF08807.10 KPA42375.1 - 0.064 13.4 0.0 20 5.4 0.0 3.3 3 0 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) AMP-binding PF00501.28 KPA42376.1 - 1.3e-57 195.3 0.0 1.6e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA42376.1 - 5.3e-16 59.4 0.2 1e-15 58.5 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_membrane PF00664.23 KPA42377.1 - 3.8e-88 295.7 31.2 8.4e-50 169.9 5.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA42377.1 - 2.1e-61 206.4 0.0 1.7e-30 106.3 0.0 3.4 3 0 0 3 3 3 3 ABC transporter SMC_N PF02463.19 KPA42377.1 - 5.8e-15 55.3 0.4 8.5e-05 22.1 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPA42377.1 - 2.5e-08 33.5 0.6 0.00038 20.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KPA42377.1 - 1.6e-07 31.6 0.1 0.056 13.7 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KPA42377.1 - 3.5e-07 30.3 0.0 0.2 11.5 0.0 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KPA42377.1 - 1.3e-06 28.9 3.5 0.15 12.4 0.0 4.3 4 1 0 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 KPA42377.1 - 1.3e-06 28.4 0.0 0.089 12.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KPA42377.1 - 3.5e-05 23.6 3.4 0.46 10.2 0.0 4.6 5 0 0 5 5 5 2 AAA domain AAA_15 PF13175.6 KPA42377.1 - 3.9e-05 23.5 0.0 0.047 13.4 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 KPA42377.1 - 4.3e-05 23.1 0.0 0.095 12.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 KPA42377.1 - 5.4e-05 23.2 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_23 PF13476.6 KPA42377.1 - 7.7e-05 23.3 0.1 0.4 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KPA42377.1 - 9.7e-05 22.4 0.0 0.81 9.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 KPA42377.1 - 0.00011 22.6 3.2 1.5 9.3 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KPA42377.1 - 0.00015 21.4 1.4 0.83 9.2 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KPA42377.1 - 0.00015 22.3 0.0 0.59 10.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KPA42377.1 - 0.00025 21.3 0.0 0.99 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 KPA42377.1 - 0.00057 19.6 0.0 1.3 8.6 0.0 2.8 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 KPA42377.1 - 0.0015 18.3 0.8 0.91 9.2 0.0 3.4 4 0 0 4 4 3 1 IstB-like ATP binding protein SbcCD_C PF13558.6 KPA42377.1 - 0.0037 17.5 4.0 3.2 8.0 0.4 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 KPA42377.1 - 0.007 15.6 0.1 0.2 10.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 KPA42377.1 - 0.0073 16.5 0.2 5.5 7.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPA42377.1 - 0.009 15.8 0.4 3.8 7.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 KPA42377.1 - 0.014 14.2 1.5 2.5 6.8 0.0 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class SRP54 PF00448.22 KPA42377.1 - 0.018 14.6 0.0 7.1 6.2 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain TniB PF05621.11 KPA42377.1 - 0.021 14.3 0.0 7.8 5.9 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein ATP_bind_1 PF03029.17 KPA42377.1 - 0.026 14.3 0.0 2.7 7.7 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KPA42377.1 - 0.04 14.3 0.0 9.5 6.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Dala_Dala_lig_N PF01820.21 KPA42377.1 - 0.09 13.3 0.0 11 6.5 0.0 2.7 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus CHD5 PF04420.14 KPA42377.1 - 0.09 12.6 0.3 0.24 11.2 0.3 1.7 1 0 0 1 1 1 0 CHD5-like protein AAA_17 PF13207.6 KPA42377.1 - 0.11 12.9 0.4 24 5.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.20 KPA42377.1 - 0.13 11.4 0.0 14 4.7 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Thioesterase PF00975.20 KPA42378.1 - 7.6e-12 45.8 0.0 1.7e-11 44.7 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KPA42378.1 - 0.0013 19.4 1.3 0.0066 17.1 1.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KPA42378.1 - 0.0068 16.0 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 KPA42378.1 - 0.01 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Tom6 PF17112.5 KPA42378.1 - 0.18 11.3 0.3 54 3.4 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom6, fungal Sod_Cu PF00080.20 KPA42379.1 - 2.3e-48 164.0 4.3 2.6e-48 163.8 4.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.17 KPA42380.1 - 2.5e-70 233.8 5.3 6.7e-21 74.8 0.0 5.6 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KPA42380.1 - 2.7e-21 75.9 0.0 7.6e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 KPA42380.1 - 0.00025 20.4 0.1 0.00081 18.7 0.0 1.8 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) TAL_FSA PF00923.19 KPA42381.1 - 1.6e-95 319.7 0.4 1.9e-95 319.5 0.4 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 KPA42381.1 - 0.066 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Cas_VVA1548 PF09652.10 KPA42381.1 - 0.09 13.0 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) Metallophos PF00149.28 KPA42382.1 - 3.4e-12 47.3 0.0 7.5e-12 46.2 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPA42382.1 - 1.4e-08 35.2 0.0 1.8e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KPA42382.1 - 0.02 14.2 0.5 0.037 13.4 0.1 1.5 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Borrelia_P83 PF05262.11 KPA42382.1 - 0.073 11.6 1.2 0.1 11.1 1.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Caudo_TAP PF02413.17 KPA42382.1 - 0.25 11.5 3.3 0.9 9.7 1.7 2.1 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Pet191_N PF10203.9 KPA42383.1 - 1.3e-26 92.7 4.9 1.7e-26 92.3 4.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 KPA42383.1 - 0.081 12.9 5.1 0.31 11.1 0.5 2.7 2 1 1 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, PAN_3 PF08277.12 KPA42383.1 - 0.11 12.3 0.4 0.2 11.5 0.4 1.4 1 0 0 1 1 1 0 PAN-like domain Cmc1 PF08583.10 KPA42383.1 - 4.3 7.4 9.1 2.2 8.4 1.0 2.7 2 1 0 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pal1 PF08316.11 KPA42385.1 - 6.8e-45 153.2 1.3 6.8e-45 153.2 1.3 2.8 2 1 0 2 2 2 1 Pal1 cell morphology protein adh_short PF00106.25 KPA42386.1 - 8.9e-19 67.7 0.0 1.2e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA42386.1 - 1.5e-12 47.6 0.0 2.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPA42386.1 - 0.0085 15.6 0.0 0.024 14.1 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPA42386.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.7 1 1 0 1 1 1 0 KR domain RabGAP-TBC PF00566.18 KPA42387.1 - 1.3e-46 159.0 0.1 2.4e-46 158.1 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 KPA42387.1 - 2e-05 24.1 1.0 0.024 14.6 0.3 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KPA42387.1 - 0.0027 17.1 1.3 0.11 12.2 0.7 3.2 2 0 0 2 2 2 1 EF hand GRAM PF02893.20 KPA42387.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.6 KPA42387.1 - 0.0062 17.0 0.7 0.056 13.9 0.9 2.4 1 1 2 3 3 3 2 EF-hand domain pair Pkinase PF00069.25 KPA42388.1 - 3.4e-64 216.7 0.0 4.9e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA42388.1 - 9.4e-30 103.7 0.0 1.2e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA42388.1 - 3.1e-05 23.4 0.0 4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KPA42388.1 - 0.00025 21.0 0.3 0.011 15.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KPA42388.1 - 0.018 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KPA42388.1 - 0.04 12.9 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KPA42388.1 - 0.048 12.7 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Exo_endo_phos PF03372.23 KPA42389.1 - 1.8e-06 27.6 0.0 3.4e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DND1_DSRM PF14709.7 KPA42389.1 - 0.15 12.4 0.0 0.38 11.1 0.0 1.7 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Pkinase PF00069.25 KPA42390.1 - 2.4e-26 92.7 0.0 3.1e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA42390.1 - 6.8e-14 51.8 0.0 9.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPA42390.1 - 3.9e-09 35.8 0.0 6.4e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KPA42390.1 - 0.00017 21.6 0.0 0.0014 18.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family RNA_pol_Rpb2_6 PF00562.28 KPA42393.1 - 0.23 10.5 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Peptidase_C1_2 PF03051.15 KPA42395.1 - 4.5e-150 500.2 0.0 5.2e-150 500.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KPA42395.1 - 1.6e-07 31.6 0.1 0.0049 17.0 0.0 2.5 2 1 0 2 2 2 2 Papain family cysteine protease VirDNA-topo-I_N PF09266.10 KPA42396.1 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal NFACT-C PF11923.8 KPA42397.1 - 3e-42 142.9 0.6 3e-42 142.9 0.6 4.3 4 0 0 4 4 4 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 KPA42397.1 - 9.4e-33 113.1 0.0 1.9e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 KPA42397.1 - 3.1e-32 111.9 10.6 3.1e-32 111.9 10.6 2.1 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Serine_rich PF08824.10 KPA42397.1 - 0.07 13.1 1.6 0.13 12.2 0.2 2.1 2 0 0 2 2 2 0 Serine rich protein interaction domain GREB1 PF15782.5 KPA42397.1 - 0.4 7.8 15.3 0.66 7.0 15.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Annexin PF00191.20 KPA42398.1 - 4.7e-19 68.2 1.8 1.2e-05 25.2 0.2 4.4 4 0 0 4 4 4 4 Annexin Sporozoite_P67 PF05642.11 KPA42398.1 - 0.13 10.3 0.3 0.25 9.4 0.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_A21 PF03566.13 KPA42398.1 - 0.19 10.0 3.0 0.42 8.8 3.0 1.5 1 0 0 1 1 1 0 Peptidase family A21 MAJIN PF15077.6 KPA42398.1 - 6.3 6.5 9.4 14 5.4 9.4 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein Methyltransf_32 PF13679.6 KPA42399.1 - 0.054 13.5 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KPA42400.1 - 3.5e-26 92.0 0.0 5.3e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA42400.1 - 1.8e-12 47.8 0.0 6.5e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA42400.1 - 3e-11 43.8 0.0 6.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA42400.1 - 6.2e-09 36.5 0.0 6.4e-08 33.3 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA42400.1 - 1.2e-08 34.9 0.0 0.005 16.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.20 KPA42400.1 - 7.2e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KPA42400.1 - 0.00035 20.1 0.0 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KPA42400.1 - 0.015 14.8 0.0 0.051 13.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KPA42400.1 - 0.033 13.9 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KPA42400.1 - 0.049 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KPA42400.1 - 0.059 12.7 0.0 0.69 9.2 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KPA42400.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KPA42401.1 - 8.5e-23 80.8 0.0 1.3e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KPA42401.1 - 0.0081 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA42401.1 - 0.067 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KPA42401.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 KPA42401.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Grg1 PF11034.8 KPA42402.1 - 4.7e-32 110.0 13.0 5.4e-32 109.8 13.0 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 BSD PF03909.17 KPA42403.1 - 2.3e-18 65.9 0.2 4.6e-18 65.0 0.2 1.5 1 0 0 1 1 1 1 BSD domain Phage_Gp111 PF07410.11 KPA42403.1 - 0.027 15.0 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein DUF4303 PF14136.6 KPA42403.1 - 0.66 9.7 6.4 1.1 9.0 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4303) WGG PF10273.9 KPA42404.1 - 6.1e-34 116.5 0.1 1.1e-33 115.8 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Abhydrolase_3 PF07859.13 KPA42405.1 - 1.8e-39 135.8 0.1 1.4e-29 103.5 0.1 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPA42405.1 - 6.2e-13 48.4 0.0 1.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KPA42405.1 - 0.00011 21.2 0.0 0.0096 14.8 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family DUF3089 PF11288.8 KPA42405.1 - 0.18 11.3 0.4 2.2 7.8 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3089) MRP-L27 PF09809.9 KPA42406.1 - 1.7e-16 60.0 0.6 2e-16 59.8 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Gryzun PF07919.12 KPA42407.1 - 2e-190 634.5 0.0 2.7e-190 634.1 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KPA42407.1 - 1.8e-87 293.2 3.7 2.4e-82 276.4 3.4 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 MFS_1 PF07690.16 KPA42407.1 - 4.4e-33 114.7 56.1 1.9e-32 112.6 55.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA42407.1 - 1.1e-10 40.6 20.4 1.8e-10 39.9 20.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) REPA_OB_2 PF16900.5 KPA42408.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Replication protein A OB domain Abhydrolase_6 PF12697.7 KPA42409.1 - 1.1e-09 39.3 4.5 2.4e-09 38.2 4.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA42409.1 - 2.6e-06 26.9 0.0 4.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KPA42409.1 - 0.0018 17.0 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 KPA42409.1 - 0.017 14.7 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Piwi PF02171.17 KPA42410.1 - 9.2e-66 222.1 0.0 1.3e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 KPA42410.1 - 7.2e-11 42.3 0.0 3e-10 40.3 0.0 2.2 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoN PF16486.5 KPA42410.1 - 7.2e-09 36.4 0.0 1.5e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KPA42410.1 - 7.6e-08 31.9 0.9 2e-07 30.6 0.9 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KPA42410.1 - 1.7e-05 25.0 0.1 8.5e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 Mid domain of argonaute PAZ PF02170.22 KPA42410.1 - 0.00019 21.2 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 PAZ domain SMI1_KNR4 PF09346.10 KPA42411.1 - 1.2e-07 32.2 0.0 3.5e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 KPA42411.1 - 4.1e-05 23.3 0.0 0.00022 21.0 0.0 2.2 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall SUKH_6 PF14568.6 KPA42411.1 - 9.9e-05 22.7 0.0 0.00041 20.7 0.0 2.1 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall Cornifin PF02389.15 KPA42412.1 - 0.04 14.1 1.7 0.057 13.6 1.7 1.4 1 1 0 1 1 1 0 Cornifin (SPRR) family EcKinase PF02958.20 KPA42413.1 - 3.8e-16 59.3 0.0 7.9e-11 41.8 0.2 2.2 1 1 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 KPA42413.1 - 1.3e-07 30.9 0.1 1.9e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 KPA42413.1 - 2.2e-07 31.0 2.2 3.4e-07 30.4 2.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family SLAC1 PF03595.17 KPA42414.1 - 1e-80 271.4 44.5 1.2e-80 271.2 44.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MR_MLE_C PF13378.6 KPA42416.1 - 2.3e-48 164.7 0.2 3e-48 164.3 0.2 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MFS_1 PF07690.16 KPA42417.1 - 2.4e-37 128.7 28.1 2.4e-37 128.7 28.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 KPA42417.1 - 0.0057 16.4 0.6 2.1 8.2 0.0 2.8 2 0 0 2 2 2 2 Bacteriophage holin family, superfamily II-like SpoVAB PF13782.6 KPA42417.1 - 0.012 15.9 0.5 0.012 15.9 0.5 2.7 2 2 2 4 4 4 0 Stage V sporulation protein AB DHDPS PF00701.22 KPA42418.1 - 2.3e-43 148.0 0.0 2.7e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TPR_10 PF13374.6 KPA42418.1 - 0.038 13.9 0.3 9.3 6.3 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.25 KPA42419.1 - 2.8e-53 180.3 0.0 3.7e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA42419.1 - 1.9e-35 122.5 0.0 2.3e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA42419.1 - 1.6e-13 51.0 0.0 2.3e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA42419.1 - 0.0012 18.1 0.2 0.0029 16.8 0.2 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPA42419.1 - 0.0042 16.6 0.1 0.016 14.7 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KPA42419.1 - 0.012 15.8 0.1 0.023 14.9 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 KPA42419.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Fungal_trans PF04082.18 KPA42420.1 - 3.1e-35 121.5 0.0 5.2e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RCC1 PF00415.18 KPA42421.1 - 7.2e-22 77.8 0.0 1.2e-06 29.0 0.1 4.9 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KPA42421.1 - 1.2e-10 41.5 0.0 5.9e-09 36.1 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain Ank_4 PF13637.6 KPA42421.1 - 1e-09 38.7 0.1 2.9e-09 37.3 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 KPA42421.1 - 3e-06 26.9 0.5 3e-06 26.9 0.5 4.0 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 KPA42421.1 - 4.2e-06 27.2 0.0 1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA42421.1 - 9.6e-05 22.5 0.1 1 10.1 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KPA42421.1 - 0.058 13.7 0.1 0.25 11.7 0.1 2.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Mito_carr PF00153.27 KPA42422.1 - 2.6e-69 229.2 1.3 2.4e-26 91.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pept_tRNA_hydro PF01195.19 KPA42422.1 - 0.035 14.1 0.0 0.92 9.5 0.0 2.1 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase Tim17 PF02466.19 KPA42422.1 - 0.044 14.1 0.8 0.18 12.2 0.8 2.3 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Serine_protease PF18405.1 KPA42422.1 - 0.15 11.2 1.3 9 5.3 0.0 3.3 3 1 1 4 4 4 0 Gammaproteobacterial serine protease YabA PF06156.13 KPA42423.1 - 0.044 14.4 0.1 0.14 12.8 0.0 1.8 2 0 0 2 2 2 0 Initiation control protein YabA ENTH PF01417.20 KPA42424.1 - 9.5e-51 171.1 0.1 1.6e-50 170.3 0.1 1.4 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 KPA42424.1 - 7.6e-05 23.0 50.4 7.6e-05 23.0 50.4 6.4 1 1 1 2 2 2 1 Domain of unknown function (DUF1720) ANTH PF07651.16 KPA42424.1 - 0.0061 15.6 0.0 0.0096 14.9 0.0 1.3 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KPA42424.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 VHS domain UIM PF02809.20 KPA42424.1 - 0.029 14.3 9.0 0.073 13.0 2.0 3.0 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF4264 PF14084.6 KPA42424.1 - 0.19 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) EF-hand_7 PF13499.6 KPA42425.1 - 1.4e-19 70.3 6.9 5.4e-12 46.0 2.0 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KPA42425.1 - 1.5e-14 52.4 5.9 3.9e-06 26.0 0.5 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KPA42425.1 - 4.3e-14 52.1 8.9 6.3e-12 45.2 2.5 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KPA42425.1 - 1e-12 46.9 2.4 4.1e-05 23.2 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KPA42425.1 - 1.3e-07 30.8 2.4 1.1e-05 24.6 0.2 3.3 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 KPA42425.1 - 0.0017 18.6 0.2 0.022 15.1 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 KPA42425.1 - 0.011 15.7 0.1 4.8 7.2 0.0 2.9 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Nup96 PF12110.8 KPA42426.1 - 3.3e-93 312.0 0.3 6.6e-93 311.0 0.3 1.5 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KPA42426.1 - 4.2e-49 166.5 0.0 7.6e-49 165.6 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KPA42426.1 - 1.8e-24 86.4 355.4 1.3e-09 38.8 41.2 11.2 4 2 5 10 10 10 4 Nucleoporin FG repeat region MOZ_SAS PF01853.18 KPA42429.1 - 7e-76 253.9 0.1 1e-75 253.4 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KPA42429.1 - 6.1e-20 70.6 5.0 1.6e-19 69.3 5.0 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 KPA42429.1 - 3.6e-09 36.6 8.4 1.2e-08 34.9 8.4 2.0 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KPA42429.1 - 0.00081 19.2 1.0 0.0022 17.9 1.0 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KPA42429.1 - 0.00086 19.2 9.5 0.00086 19.2 9.5 2.4 2 1 0 2 2 2 1 PHD-finger Rubredoxin PF00301.20 KPA42429.1 - 0.042 13.9 3.6 0.14 12.2 0.3 3.0 2 0 0 2 2 2 0 Rubredoxin PHD_2 PF13831.6 KPA42429.1 - 0.096 12.3 0.9 0.26 10.9 0.9 1.8 1 0 0 1 1 1 0 PHD-finger Acetyltransf_7 PF13508.7 KPA42429.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-MIZ PF02891.20 KPA42429.1 - 5.4 6.9 5.9 3.6 7.4 3.8 1.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger MWFE PF15879.5 KPA42430.1 - 1.4e-23 82.7 0.0 1.6e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit ATP_bind_3 PF01171.20 KPA42431.1 - 3e-19 69.5 0.0 4.9e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KPA42431.1 - 5.3e-17 61.0 4.3 5.3e-17 61.0 4.3 3.1 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 KPA42431.1 - 0.06 12.1 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase RecR PF02132.15 KPA42431.1 - 0.14 11.8 0.3 0.14 11.8 0.3 3.0 4 0 0 4 4 4 0 RecR protein zf-UBR PF02207.20 KPA42431.1 - 0.63 10.2 7.4 6.8 6.9 0.6 2.8 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Ribosomal_L7Ae PF01248.26 KPA42432.1 - 1.8e-21 75.7 1.0 1.8e-21 75.7 1.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KPA42432.1 - 0.012 15.7 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 CLPTM1 PF05602.12 KPA42432.1 - 0.043 12.8 0.4 0.053 12.5 0.4 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) NTF2 PF02136.20 KPA42433.1 - 9e-32 110.2 0.2 1e-31 110.0 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KPA42433.1 - 0.0011 19.3 0.0 0.0012 19.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Apocytochr_F_N PF16639.5 KPA42433.1 - 0.14 12.4 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Apocytochrome F, N-terminal Cwf_Cwc_15 PF04889.12 KPA42434.1 - 0.029 14.1 12.6 0.47 10.2 1.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Seipin PF06775.14 KPA42435.1 - 3.9e-55 187.0 1.7 5.2e-55 186.6 1.7 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) FCH PF00611.23 KPA42436.1 - 2.3e-16 59.8 0.1 7e-16 58.3 0.1 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KPA42436.1 - 3.6e-12 45.7 0.0 7.1e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPA42436.1 - 3.6e-11 42.7 0.1 8.8e-11 41.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPA42436.1 - 2.4e-10 39.9 0.0 1.2e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Not1 PF04054.15 KPA42437.1 - 5.9e-121 403.8 0.7 1.2e-120 402.8 0.2 1.8 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KPA42437.1 - 8.9e-93 309.8 0.4 2e-92 308.7 0.4 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KPA42437.1 - 3.8e-49 166.4 2.2 3.8e-49 166.4 2.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KPA42437.1 - 1.9e-43 147.8 0.0 1.1e-42 145.4 0.0 2.2 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KPA42437.1 - 1.3e-40 138.9 0.0 4e-40 137.3 0.0 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Xpo1 PF08389.12 KPA42437.1 - 0.04 14.0 1.0 2 8.4 0.0 4.2 4 0 0 4 4 4 0 Exportin 1-like protein PhzC-PhzF PF02567.16 KPA42438.1 - 1.2e-34 120.1 0.2 9.1e-34 117.2 0.2 1.9 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein ATP11 PF06644.11 KPA42439.1 - 0.2 11.4 2.7 0.4 10.4 2.7 1.4 1 0 0 1 1 1 0 ATP11 protein DUF4698 PF15769.5 KPA42439.1 - 0.28 10.2 2.6 0.41 9.7 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) SR-25 PF10500.9 KPA42439.1 - 0.69 9.5 12.8 1.8 8.1 12.8 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 KPA42439.1 - 2.6 8.9 12.0 3.5 8.5 10.5 2.0 2 0 0 2 2 2 0 Chorion family 2 Methyltransf_23 PF13489.6 KPA42440.1 - 9.6e-17 61.3 0.0 1.4e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA42440.1 - 6.5e-06 26.8 0.0 0.033 14.9 0.0 3.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KPA42440.1 - 4.9e-05 23.9 0.0 0.00087 19.9 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA42440.1 - 7.6e-05 23.4 0.0 0.00055 20.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA42440.1 - 0.0004 19.8 0.0 0.045 13.1 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KPA42440.1 - 0.00091 19.1 0.0 0.39 10.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain UPF0029 PF01205.19 KPA42441.1 - 1.2e-24 86.6 0.0 2.9e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Pkinase PF00069.25 KPA42442.1 - 7.7e-70 235.3 0.0 9.6e-70 234.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA42442.1 - 5.8e-31 107.7 0.0 7.2e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA42442.1 - 0.00097 18.5 0.0 0.0018 17.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KPA42442.1 - 0.00099 18.1 0.0 0.0084 15.1 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KPA42442.1 - 0.0061 15.6 0.1 0.0089 15.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KPA42442.1 - 0.0072 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cyclin_N PF00134.23 KPA42443.1 - 5.9e-14 51.9 0.8 8.2e-14 51.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 KPA42443.1 - 4.7e-07 30.3 0.1 1.3e-06 28.9 0.1 1.8 1 0 0 1 1 1 1 Cyclin E1-E2_ATPase PF00122.20 KPA42444.1 - 3.4e-49 166.8 1.6 3.4e-49 166.8 1.6 2.3 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KPA42444.1 - 1.4e-36 126.8 0.2 2.6e-36 125.9 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KPA42444.1 - 6.2e-17 61.8 0.1 2.2e-10 40.8 0.1 3.9 4 0 0 4 4 4 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KPA42444.1 - 3.8e-06 26.8 0.6 0.00012 21.9 0.2 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPA42444.1 - 0.0013 19.2 0.0 0.0039 17.6 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Importin_rep_3 PF18806.1 KPA42444.1 - 0.031 14.3 0.0 0.098 12.7 0.0 1.8 1 0 0 1 1 1 0 Importin 13 repeat SDF PF00375.18 KPA42445.1 - 3.5e-85 286.4 36.6 4.2e-85 286.1 36.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family NAD_binding_10 PF13460.6 KPA42446.1 - 2.3e-06 27.6 0.0 3.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KPA42446.1 - 0.0092 15.2 0.0 0.049 12.8 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 KPA42446.1 - 0.1 12.5 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 KR domain Epimerase PF01370.21 KPA42446.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_S8 PF00082.22 KPA42447.1 - 9.6e-37 126.8 4.3 1.3e-36 126.4 4.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KPA42447.1 - 1.6e-16 60.7 0.0 3.8e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 BTB PF00651.31 KPA42449.1 - 7.5e-07 29.4 0.1 8.1e-06 26.0 0.0 2.4 3 0 0 3 3 3 1 BTB/POZ domain DUF1835 PF08874.10 KPA42449.1 - 0.0049 17.1 0.0 0.068 13.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1835) DUF883 PF05957.13 KPA42450.1 - 0.0017 18.9 0.7 0.028 15.0 0.2 2.6 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) Mod_r PF07200.13 KPA42450.1 - 0.03 14.4 2.4 0.062 13.4 2.4 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein PolyA_pol_RNAbd PF12627.7 KPA42450.1 - 0.037 13.8 0.1 7.8 6.3 0.0 2.9 3 0 0 3 3 3 0 Probable RNA and SrmB- binding site of polymerase A ANAPC4 PF12896.7 KPA42450.1 - 0.084 12.4 0.3 0.14 11.6 0.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Atg14 PF10186.9 KPA42450.1 - 0.25 10.4 3.2 0.15 11.1 0.9 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Complex1_LYR PF05347.15 KPA42451.1 - 2.7e-11 43.4 0.5 3.6e-11 42.9 0.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Histone_H2A_C PF16211.5 KPA42452.1 - 2.2e-21 75.3 3.1 3.8e-21 74.5 3.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KPA42452.1 - 7e-17 62.0 0.0 9.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KPA42452.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KPA42453.1 - 3.4e-22 79.2 2.5 4.3e-22 78.9 2.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KPA42453.1 - 1.9e-05 24.8 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KPA42453.1 - 0.00032 21.1 0.0 0.00056 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KPA42453.1 - 0.048 13.3 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain R3H PF01424.22 KPA42454.1 - 2.3e-15 56.3 0.0 4.3e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KPA42454.1 - 2.1e-08 33.9 2.5 5.4e-08 32.6 2.5 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KPA42454.1 - 9.1e-05 22.5 0.9 9.1e-05 22.5 0.9 2.5 2 0 0 2 2 2 1 G-patch domain Herpes_DNAp_acc PF04929.12 KPA42454.1 - 4.1 6.3 4.9 6.5 5.6 4.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Peptidase_C54 PF03416.19 KPA42455.1 - 7.4e-71 238.8 0.0 3e-45 154.8 0.0 2.2 1 1 1 2 2 2 2 Peptidase family C54 DnaJ PF00226.31 KPA42456.1 - 2.2e-23 82.2 0.5 2.2e-23 82.2 0.5 2.6 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 KPA42456.1 - 8.2e-11 41.9 3.0 1.7e-10 40.9 3.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPA42456.1 - 1.8e-09 37.7 2.5 4.2e-09 36.5 2.5 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KPA42456.1 - 0.0002 21.6 1.7 0.00045 20.5 1.7 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KPA42456.1 - 0.0035 17.7 0.5 0.0091 16.4 0.5 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KPA42456.1 - 0.0037 17.2 3.0 0.0074 16.3 3.0 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KPA42456.1 - 0.0046 17.7 0.3 0.013 16.3 0.3 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C3HC PF07967.13 KPA42456.1 - 0.013 15.5 0.5 0.033 14.2 0.5 1.8 1 0 0 1 1 1 0 C3HC zinc finger-like DUF3926 PF13080.6 KPA42456.1 - 0.11 12.5 0.1 0.43 10.6 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Unpaired PF15972.5 KPA42456.1 - 0.11 12.0 6.3 0.035 13.7 1.7 2.2 2 0 0 2 2 2 0 Unpaired protein zf-C2H2_3rep PF18868.1 KPA42456.1 - 0.16 12.6 1.9 0.65 10.7 1.9 2.0 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats SPX PF03105.19 KPA42457.1 - 2.9e-68 231.5 3.9 4.6e-68 230.9 3.9 1.3 1 0 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.25 KPA42457.1 - 3.2e-08 33.3 10.6 6.7e-08 32.3 10.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPA42457.1 - 5.7e-08 32.5 9.0 1.1e-07 31.6 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA42457.1 - 1.1e-07 31.6 10.8 2.4e-07 30.5 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPA42457.1 - 3.7e-06 27.0 10.0 8.7e-06 25.8 10.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KPA42457.1 - 4.2e-06 27.0 10.9 9.1e-06 25.9 10.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KPA42457.1 - 3.6e-05 23.7 8.3 8.2e-05 22.6 8.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPA42457.1 - 3.9e-05 23.5 8.6 9.2e-05 22.3 8.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KPA42457.1 - 0.016 15.1 8.4 0.042 13.7 8.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KPA42457.1 - 0.023 14.5 5.6 0.023 14.5 5.6 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SFTA2 PF15210.6 KPA42457.1 - 0.079 12.9 0.1 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Surfactant-associated protein 2 MCPVI PF02993.14 KPA42457.1 - 0.089 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Minor capsid protein VI zf-ANAPC11 PF12861.7 KPA42457.1 - 0.1 12.7 2.3 0.2 11.7 2.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KPA42457.1 - 0.38 11.1 9.5 1 9.7 9.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain FYVE_2 PF02318.16 KPA42457.1 - 0.58 10.4 6.4 0.53 10.5 4.4 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger zf-RING_10 PF16685.5 KPA42457.1 - 0.98 9.6 8.8 1.8 8.7 8.4 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_5 PF17121.5 KPA42457.1 - 7.7 6.5 9.2 34 4.4 9.3 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cys_Met_Meta_PP PF01053.20 KPA42458.1 - 1.1e-31 109.7 0.0 1.5e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KPA42458.1 - 0.0075 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Podoplanin PF05808.11 KPA42459.1 - 0.089 12.9 0.3 0.089 12.9 0.3 2.5 2 0 0 2 2 2 0 Podoplanin EMG1 PF03587.14 KPA42460.1 - 1.2e-78 263.2 0.1 1.4e-78 263.0 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ribosomal_S17 PF00366.20 KPA42461.1 - 1.8e-21 76.0 0.5 3.3e-21 75.2 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 NARP1 PF12569.8 KPA42461.1 - 0.53 9.1 10.0 0.67 8.8 10.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Menin PF05053.13 KPA42461.1 - 9.2 4.5 9.2 13 4.0 9.2 1.1 1 0 0 1 1 1 0 Menin AAA PF00004.29 KPA42462.1 - 4.9e-38 130.5 0.0 8.9e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA42462.1 - 2.5e-08 33.6 0.0 6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KPA42462.1 - 3.3e-08 33.4 0.0 4.6e-07 29.7 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KPA42462.1 - 1.9e-05 25.0 1.1 0.00089 19.5 0.2 3.4 2 1 0 3 3 2 1 AAA domain RuvB_N PF05496.12 KPA42462.1 - 9.6e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KPA42462.1 - 0.00062 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KPA42462.1 - 0.00065 20.1 2.1 0.0033 17.8 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KPA42462.1 - 0.0022 18.1 0.0 0.0052 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KPA42462.1 - 0.0028 17.6 0.3 0.01 15.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KPA42462.1 - 0.0038 16.7 0.6 0.0099 15.3 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KPA42462.1 - 0.0056 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KPA42462.1 - 0.011 15.9 0.0 0.039 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KPA42462.1 - 0.013 14.6 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KPA42462.1 - 0.035 14.1 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KPA42462.1 - 0.044 14.1 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KPA42462.1 - 0.05 13.2 0.0 0.17 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KPA42462.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KPA42462.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KPA42462.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KPA42462.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KPA42462.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 KPA42462.1 - 0.16 11.4 0.1 0.51 9.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 KPA42462.1 - 0.82 8.8 2.5 2 7.6 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) COG6 PF06419.11 KPA42463.1 - 5.9e-210 698.7 8.6 6.8e-210 698.5 8.6 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 GARP PF16731.5 KPA42463.1 - 0.043 13.5 4.9 1.9 8.1 1.0 2.8 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DASH_Dad3 PF08656.10 KPA42463.1 - 0.045 13.8 2.6 0.12 12.5 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad3 APG9 PF04109.16 KPA42465.1 - 1e-195 651.3 14.1 1.2e-195 651.1 14.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Cation_ATPase_C PF00689.21 KPA42465.1 - 0.27 10.9 3.7 0.068 12.9 0.4 1.6 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Mito_carr PF00153.27 KPA42466.1 - 2.1e-67 223.1 7.3 1.9e-23 82.2 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPA42466.1 - 0.0067 15.6 4.8 0.35 10.0 4.1 3.2 1 1 1 2 2 2 1 Gammaproteobacterial serine protease DnaJ PF00226.31 KPA42467.1 - 2.1e-20 72.6 1.8 2.1e-20 72.6 1.8 2.9 3 1 1 4 4 3 1 DnaJ domain TPR_1 PF00515.28 KPA42467.1 - 3e-18 64.8 0.1 0.0026 17.5 0.0 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KPA42467.1 - 1.1e-16 60.8 0.0 0.00012 22.1 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPA42467.1 - 3.9e-16 57.8 1.4 0.023 14.8 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KPA42467.1 - 8.1e-14 51.9 1.7 6.8e-05 23.3 0.4 4.2 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KPA42467.1 - 1.1e-12 47.1 0.0 0.039 14.2 0.2 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KPA42467.1 - 1.6e-12 47.1 0.2 0.052 14.4 0.0 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KPA42467.1 - 1.9e-09 37.0 1.5 0.036 13.7 0.1 4.5 2 2 2 4 4 4 3 TPR repeat TPR_6 PF13174.6 KPA42467.1 - 7.5e-09 35.7 2.7 3.7 8.4 0.1 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KPA42467.1 - 1.1e-08 34.9 3.6 0.00064 19.9 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPA42467.1 - 3.1e-07 30.0 0.4 1.4 9.1 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPA42467.1 - 8.7e-07 29.5 5.3 2.1 9.1 0.1 5.5 4 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA42467.1 - 4.7e-06 26.7 2.4 0.44 10.8 0.0 4.8 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 KPA42467.1 - 1.8e-05 23.6 0.4 0.0022 16.8 0.3 2.8 2 1 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_12 PF13424.6 KPA42467.1 - 2e-05 24.8 10.1 0.28 11.5 0.1 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KPA42467.1 - 0.98 9.4 3.9 16 5.5 0.2 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RXLR PF16810.5 KPA42467.1 - 3.4 8.1 5.5 0.58 10.6 0.4 2.4 3 0 0 3 3 3 0 RXLR phytopathogen effector protein, Avirulence activity CLZ PF16526.5 KPA42468.1 - 0.019 15.3 2.1 0.54 10.7 0.0 3.1 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_23 PF13476.6 KPA42468.1 - 0.13 12.8 0.6 0.41 11.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain DUF2408 PF10303.9 KPA42468.1 - 0.45 11.1 7.7 6.9 7.2 7.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) COG2 PF06148.11 KPA42468.1 - 0.85 9.7 8.8 0.54 10.3 2.1 2.7 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4404 PF14357.6 KPA42468.1 - 1.1 9.9 16.0 2.9 8.6 0.6 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) Nup54 PF13874.6 KPA42468.1 - 1.9 8.6 8.3 0.21 11.7 3.3 2.0 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Med10 PF09748.9 KPA42468.1 - 2.6 8.0 6.0 22 5.0 0.0 3.3 3 1 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex Vac14_Fig4_bd PF11916.8 KPA42469.1 - 4.1e-80 267.7 6.2 4.1e-80 267.7 6.2 1.8 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KPA42469.1 - 9.5e-46 154.3 0.1 4.3e-41 139.4 0.0 4.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KPA42469.1 - 4.1e-10 39.0 0.3 0.00065 19.7 0.0 4.6 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 KPA42469.1 - 9.9e-09 35.5 3.2 0.001 19.5 0.2 5.3 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 KPA42469.1 - 7.1e-07 29.4 1.4 0.025 14.6 0.3 3.6 3 0 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KPA42469.1 - 0.00013 22.2 0.2 0.97 9.9 0.0 4.2 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.23 KPA42469.1 - 0.003 17.5 0.0 0.51 10.5 0.0 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 KPA42469.1 - 0.0093 15.1 0.0 1.7 7.7 0.0 3.3 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal RasGEF_N_2 PF14663.6 KPA42469.1 - 0.061 13.7 0.1 4.1 7.8 0.0 3.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FA_desaturase PF00487.24 KPA42470.1 - 3.3e-30 105.8 21.5 4.9e-30 105.2 21.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KPA42470.1 - 1.3e-07 31.6 0.8 3.1e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_2 PF07992.14 KPA42471.1 - 3.5e-67 226.7 5.5 4.5e-67 226.4 5.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KPA42471.1 - 7.2e-40 135.7 0.1 3.3e-39 133.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KPA42471.1 - 7.7e-25 87.3 8.9 1.7e-21 76.5 0.6 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA42471.1 - 5.2e-11 42.6 2.9 1.7e-06 28.2 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KPA42471.1 - 6.4e-10 38.7 7.2 3e-07 29.9 3.6 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 KPA42471.1 - 7.3e-10 38.8 7.3 4.7e-09 36.1 0.3 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KPA42471.1 - 4.3e-08 32.7 1.9 0.0037 16.6 0.1 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KPA42471.1 - 1e-07 31.4 9.4 5.3e-07 29.1 2.6 3.2 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 KPA42471.1 - 1.6e-07 30.9 0.4 0.00051 19.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA42471.1 - 2.2e-06 27.5 11.5 0.0018 17.9 0.3 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA42471.1 - 2.3e-06 26.6 12.6 7.7e-05 21.6 2.1 4.0 4 0 0 4 4 4 1 HI0933-like protein Thi4 PF01946.17 KPA42471.1 - 2.3e-05 23.8 4.4 0.00011 21.5 0.2 2.5 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 KPA42471.1 - 2.4e-05 23.8 4.3 0.014 14.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 KPA42471.1 - 0.0001 21.6 0.5 0.42 9.7 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KPA42471.1 - 0.0015 17.6 3.2 0.023 13.8 0.3 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KPA42471.1 - 0.018 15.5 2.2 8.3 6.9 0.1 3.1 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KPA42471.1 - 0.078 12.9 6.0 0.096 12.6 0.2 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RuBisCO_large PF00016.20 KPA42471.1 - 0.082 12.1 3.2 1.8 7.7 0.1 3.0 3 0 0 3 3 3 0 Ribulose bisphosphate carboxylase large chain, catalytic domain 2-Hacid_dh_C PF02826.19 KPA42471.1 - 0.085 12.2 1.0 4.5 6.6 0.2 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.19 KPA42471.1 - 0.26 9.6 0.7 0.46 8.8 0.7 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Amino_oxidase PF01593.24 KPA42471.1 - 0.55 9.5 2.2 1.1 8.5 0.2 2.1 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase CSD2 PF17876.1 KPA42471.1 - 0.57 10.4 2.6 9.1 6.5 0.0 3.1 2 1 1 3 3 2 0 Cold shock domain UDPG_MGDP_dh_N PF03721.14 KPA42471.1 - 0.74 9.4 5.2 3.3 7.3 0.3 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 KPA42471.1 - 3.9 6.2 7.8 0.23 10.3 1.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase MIF4G PF02854.19 KPA42472.1 - 3.6e-23 82.3 1.3 3.5e-21 75.8 0.6 2.4 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 KPA42472.1 - 1.8e-08 34.4 0.7 1.3e-06 28.3 0.0 3.2 2 1 0 2 2 2 1 MA3 domain DUF3632 PF12311.8 KPA42472.1 - 0.0065 16.9 0.0 0.025 15.0 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF4562 PF15123.6 KPA42472.1 - 0.11 12.4 0.3 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4562) DUF1953 PF09196.10 KPA42472.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) Mpp10 PF04006.12 KPA42472.1 - 1 7.8 28.7 1.9 6.8 28.7 1.4 1 0 0 1 1 1 0 Mpp10 protein SRP14 PF02290.15 KPA42473.1 - 1.1e-28 99.4 0.1 1.8e-28 98.8 0.0 1.3 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Me-amine-dh_L PF02975.14 KPA42473.1 - 0.077 13.5 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain CHRD PF07452.12 KPA42474.1 - 2.6e-10 41.3 0.0 3.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 CHRD domain RRM_1 PF00076.22 KPA42475.1 - 1.3e-52 175.5 0.0 3.6e-17 61.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KPA42475.1 - 8.5e-06 25.8 0.1 3.6 7.7 0.0 4.3 3 2 0 3 3 3 3 Limkain b1 RRM_3 PF08777.11 KPA42475.1 - 0.00011 22.2 0.0 1.8 8.6 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif RRM_occluded PF16842.5 KPA42475.1 - 0.00028 20.7 0.0 6.5 6.7 0.0 3.4 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KPA42475.1 - 0.00065 19.3 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.10 KPA42475.1 - 0.00075 19.1 0.0 0.027 14.1 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain PknH_C PF14032.6 KPA42475.1 - 0.013 15.4 0.2 28 4.5 0.0 3.1 3 0 0 3 3 3 0 PknH-like extracellular domain COQ9 PF08511.11 KPA42476.1 - 2e-32 110.8 0.0 3e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 COQ9 SMC_N PF02463.19 KPA42477.1 - 6.1e-18 65.1 16.5 3.4e-17 62.6 16.5 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KPA42477.1 - 1.1e-09 38.6 16.2 1.1e-09 38.6 16.2 3.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KPA42477.1 - 4.6e-09 37.1 41.9 4.6e-09 37.1 41.9 5.7 3 2 0 3 3 3 1 AAA domain SMC_hinge PF06470.13 KPA42477.1 - 0.0011 19.3 0.0 0.0037 17.5 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KPA42477.1 - 0.0018 18.2 0.6 0.0018 18.2 0.6 4.8 3 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPA42477.1 - 0.0018 17.9 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KPA42477.1 - 0.02 15.1 0.0 0.072 13.3 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SGT1 PF07093.11 KPA42478.1 - 1.7e-86 291.0 19.7 7.8e-78 262.4 0.0 2.1 1 1 1 2 2 2 2 SGT1 protein THUMP PF02926.17 KPA42480.1 - 9.2e-15 55.0 3.6 3.7e-14 53.0 1.2 2.4 2 1 0 2 2 2 1 THUMP domain Coronavirus_5 PF05528.11 KPA42480.1 - 0.26 11.3 1.4 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 Coronavirus gene 5 protein TPP_enzyme_N PF02776.18 KPA42481.1 - 3.8e-34 117.8 0.0 7.7e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPA42481.1 - 1e-24 86.8 0.0 3.5e-24 85.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KPA42481.1 - 6.8e-14 51.9 0.0 5e-13 49.1 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KPA42481.1 - 0.055 12.4 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Evr1_Alr PF04777.13 KPA42482.1 - 3.6e-31 107.6 1.0 5.6e-31 107.0 0.1 1.7 2 0 0 2 2 2 1 Erv1 / Alr family APOBEC4 PF18775.1 KPA42482.1 - 0.23 11.6 0.5 0.73 10.0 0.0 1.9 2 0 0 2 2 2 0 APOBEC4 bZIP_1 PF00170.21 KPA42485.1 - 2.4e-07 30.7 9.1 2.4e-07 30.7 9.1 2.3 2 1 0 2 2 2 1 bZIP transcription factor CASP_C PF08172.12 KPA42485.1 - 0.0046 16.3 0.5 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 CASP C terminal Ribosomal_L30_N PF08079.12 KPA42485.1 - 0.33 11.2 9.1 0.64 10.3 9.1 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain bZIP_2 PF07716.15 KPA42485.1 - 2.6 8.2 15.9 7.2 6.8 8.8 2.7 2 1 0 2 2 2 0 Basic region leucine zipper SlyX PF04102.12 KPA42485.1 - 9.9 6.9 9.3 1.1 9.9 0.2 3.5 3 1 0 3 3 3 0 SlyX Pterin_4a PF01329.19 KPA42486.1 - 2.1e-20 72.6 0.4 1.1e-18 67.2 0.4 2.1 1 1 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase FA_hydroxylase PF04116.13 KPA42487.1 - 1.1e-26 93.7 15.6 1.1e-26 93.7 15.6 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily NCA2 PF08637.10 KPA42488.1 - 1.6e-108 362.3 0.1 2.8e-108 361.5 0.1 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 SNF2_N PF00176.23 KPA42489.1 - 1.3e-72 244.5 0.1 1.7e-72 244.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA42489.1 - 5.4e-15 55.7 0.0 1.3e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KPA42489.1 - 3.1e-10 39.8 13.2 3.7e-10 39.5 9.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA42489.1 - 5.6e-10 38.9 10.8 1.2e-09 37.9 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA42489.1 - 2.4e-08 33.7 11.7 5.7e-08 32.5 11.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA42489.1 - 1.2e-07 31.9 10.6 1.2e-07 31.9 10.6 2.0 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KPA42489.1 - 1.4e-07 31.2 8.6 1.4e-07 31.2 8.6 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KPA42489.1 - 6.1e-07 29.3 10.4 1.2e-06 28.4 10.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPA42489.1 - 2.7e-06 27.3 7.9 6.5e-06 26.1 7.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KPA42489.1 - 3.5e-05 24.0 6.7 8.6e-05 22.7 6.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain ResIII PF04851.15 KPA42489.1 - 0.00019 21.5 0.0 0.00072 19.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HIRAN PF08797.11 KPA42489.1 - 0.00032 20.6 0.0 0.001 18.9 0.0 1.8 2 0 0 2 2 1 1 HIRAN domain zf-C3HC4_4 PF15227.6 KPA42489.1 - 0.00098 19.2 9.9 0.0018 18.4 9.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KPA42489.1 - 0.0029 17.7 7.0 0.0074 16.4 7.0 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KPA42489.1 - 0.0041 17.1 2.6 0.0099 15.9 2.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 KPA42489.1 - 0.061 13.0 3.8 0.2 11.4 3.8 1.9 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_6 PF14835.6 KPA42489.1 - 0.12 12.2 3.8 0.33 10.9 3.8 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KPA42489.1 - 0.73 9.7 8.3 1.6 8.6 8.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KPA42489.1 - 1.1 9.0 4.4 3 7.7 4.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 KPA42489.1 - 2 8.3 7.7 4.5 7.2 7.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit LRR_8 PF13855.6 KPA42492.1 - 4e-14 52.1 6.4 7.1e-08 32.1 0.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KPA42492.1 - 1.1e-07 32.1 0.4 7.8e-07 29.3 0.4 2.4 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KPA42492.1 - 0.013 15.9 0.7 4.8 8.1 0.2 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 KPA42492.1 - 0.035 14.2 3.4 4.4 7.6 0.1 2.6 2 0 0 2 2 2 0 Leucine Rich repeat Phosducin PF02114.16 KPA42493.1 - 1.7e-12 46.9 0.1 2.4e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Phosducin NPH-II PF12011.8 KPA42493.1 - 0.077 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA helicase NPH-II Thioredoxin PF00085.20 KPA42493.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin TMA7 PF09072.10 KPA42493.1 - 0.52 11.2 3.1 4.2 8.3 0.5 2.5 2 0 0 2 2 2 0 Translation machinery associated TMA7 Ribosomal_S27e PF01667.17 KPA42494.1 - 3.5e-28 97.1 7.5 4.2e-28 96.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 KPA42494.1 - 0.14 11.7 3.5 0.19 11.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 KPA42494.1 - 1.2 9.2 7.0 2.7 8.0 4.3 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type RNR_inhib PF08591.10 KPA42495.1 - 2.7e-30 105.8 0.0 5.9e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor SIP1 PF04938.12 KPA42496.1 - 4.6e-07 29.8 0.0 0.0002 21.2 0.0 2.8 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF2868 PF11067.8 KPA42496.1 - 0.19 11.2 2.7 1.8 8.0 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) SpoIIIAH PF12685.7 KPA42496.1 - 5.3 6.8 11.6 14 5.5 11.6 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein Amidase PF01425.21 KPA42497.1 - 5.8e-114 381.5 0.1 8.2e-114 381.0 0.1 1.1 1 0 0 1 1 1 1 Amidase RNase_II_C_S1 PF18614.1 KPA42497.1 - 0.05 13.5 2.4 1.6 8.8 0.3 2.5 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain PRP38 PF03371.15 KPA42498.1 - 5.7e-58 195.6 0.0 7.7e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 PRP38 family COX16 PF14138.6 KPA42500.1 - 1.1e-33 115.6 0.3 1.7e-33 114.9 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Arc_PepC_II PF06847.11 KPA42500.1 - 0.51 10.9 1.8 1.3 9.6 0.1 2.0 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Tim17 PF02466.19 KPA42502.1 - 6e-32 110.3 7.6 7.7e-32 110.0 7.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Asparaginase_2 PF01112.18 KPA42503.1 - 7.5e-57 192.7 2.0 2.9e-27 95.5 0.1 4.1 3 2 0 3 3 3 3 Asparaginase GNAT_acetyltran PF12746.7 KPA42503.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase BLM10_mid PF16507.5 KPA42504.1 - 9.2e-200 664.7 0.0 2.2e-199 663.5 0.0 1.6 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KPA42504.1 - 1.2e-29 102.0 0.0 7.6e-29 99.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KPA42504.1 - 3e-22 78.7 0.1 8e-22 77.3 0.1 1.8 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT_EZ PF13513.6 KPA42504.1 - 0.0017 18.8 1.6 0.12 12.9 0.0 4.7 6 0 0 6 6 6 1 HEAT-like repeat HEAT PF02985.22 KPA42504.1 - 0.0024 18.0 0.2 12 6.4 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat Complex1_LYR PF05347.15 KPA42506.1 - 5.4e-11 42.4 0.0 2.1e-10 40.5 0.0 2.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) NPA PF16469.5 KPA42506.1 - 0.065 13.8 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Tropomyosin_1 PF12718.7 KPA42507.1 - 0.037 14.2 1.4 0.056 13.6 1.4 1.2 1 0 0 1 1 1 0 Tropomyosin like TPR_MLP1_2 PF07926.12 KPA42507.1 - 0.045 13.8 2.5 0.074 13.1 2.5 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 KPA42507.1 - 0.16 12.4 3.8 0.28 11.7 3.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 KPA42507.1 - 0.29 11.3 4.4 1.9 8.6 0.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Cep57_CLD_2 PF14197.6 KPA42507.1 - 0.77 9.9 6.3 5.6 7.1 2.7 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Pkinase PF00069.25 KPA42508.1 - 2.3e-29 102.6 0.0 2.8e-27 95.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA42508.1 - 1.9e-19 70.0 0.0 2.5e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase bZIP_1 PF00170.21 KPA42509.1 - 6.5e-08 32.5 0.3 1.4e-07 31.5 0.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor 3HCDH PF00725.22 KPA42509.1 - 0.016 15.8 0.3 4.3 8.0 0.0 3.3 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DDRGK PF09756.9 KPA42509.1 - 0.36 10.4 4.1 0.57 9.7 4.1 1.2 1 0 0 1 1 1 0 DDRGK domain A_deaminase PF00962.22 KPA42510.1 - 1.2e-26 93.9 0.0 1.8e-21 76.8 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KPA42510.1 - 0.00017 21.9 0.0 0.00055 20.2 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase N-terminal DUF2157 PF09925.9 KPA42511.1 - 0.031 14.1 2.1 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF2530 PF10745.9 KPA42511.1 - 0.096 12.9 0.2 0.33 11.2 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) SRP40_C PF05022.12 KPA42512.1 - 1.1e-21 77.5 1.3 1.1e-21 77.5 1.3 3.7 5 0 0 5 5 5 1 SRP40, C-terminal domain zf-C3HC PF07967.13 KPA42513.1 - 5.9e-41 139.6 0.4 4.3e-37 127.1 0.5 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KPA42513.1 - 1.4e-27 95.7 0.7 1.7e-25 89.0 0.0 2.6 2 0 0 2 2 2 2 Rsm1-like BIR PF00653.21 KPA42513.1 - 0.003 18.2 0.1 0.09 13.4 0.1 2.4 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain MMR_HSR1 PF01926.23 KPA42514.1 - 2.5e-18 66.2 0.0 6.4e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KPA42514.1 - 3e-09 37.2 0.4 0.0011 19.0 0.6 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KPA42514.1 - 2.7e-07 30.3 0.0 6.6e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPA42514.1 - 8.9e-05 22.5 0.1 0.0031 17.4 0.1 2.5 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 KPA42514.1 - 0.0037 16.8 0.1 0.0061 16.1 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 KPA42514.1 - 0.0037 16.7 0.0 0.0088 15.5 0.0 1.6 1 1 1 2 2 2 1 Bacterial TniB protein Septin PF00735.18 KPA42514.1 - 0.015 14.6 0.0 0.08 12.2 0.0 1.9 2 0 0 2 2 2 0 Septin IIGP PF05049.13 KPA42514.1 - 0.028 13.5 0.2 0.055 12.5 0.2 1.5 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KPA42514.1 - 0.038 14.2 0.2 0.29 11.4 0.2 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KPA42514.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AIG1 PF04548.16 KPA42514.1 - 0.076 12.3 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 AIG1 family 2OG-FeII_Oxy_2 PF13532.6 KPA42515.1 - 2e-29 103.2 0.0 4e-29 102.2 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily HECT PF00632.25 KPA42516.1 - 4e-63 213.7 0.0 6e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KPA42516.1 - 6.7e-24 83.9 1.6 1.7e-23 82.6 1.6 1.7 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_2 PF12756.7 KPA42517.1 - 3.4e-34 117.2 9.0 1.1e-28 99.5 1.8 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KPA42517.1 - 7.5e-10 38.8 12.9 9.3e-08 32.2 1.9 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPA42517.1 - 2e-07 31.1 4.3 6.6e-07 29.5 0.4 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KPA42517.1 - 0.00013 22.5 13.7 0.16 12.9 0.1 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-DBF PF07535.12 KPA42517.1 - 0.0019 18.3 7.8 1.4 9.0 0.4 4.4 4 0 0 4 4 4 2 DBF zinc finger zf-C2H2 PF00096.26 KPA42517.1 - 0.0061 17.0 19.9 0.33 11.5 0.2 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type SnoaL_2 PF12680.7 KPA42517.1 - 0.012 16.2 0.3 0.044 14.4 0.1 2.0 2 0 0 2 2 2 0 SnoaL-like domain DUF629 PF04780.12 KPA42517.1 - 0.047 12.2 0.4 0.1 11.1 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF629) rve PF00665.26 KPA42519.1 - 0.008 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 KPA42521.1 - 6.2e-11 42.1 1.3 1.2e-10 41.2 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle cwf18 PF08315.12 KPA42522.1 - 7.7e-46 156.1 6.7 7.7e-46 156.1 6.7 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.6 KPA42523.1 - 3.9e-17 62.2 0.0 1.3e-05 25.3 0.0 5.4 6 0 0 6 6 6 2 PPR repeat family PPR_1 PF12854.7 KPA42523.1 - 9.3e-16 57.2 0.0 3.7e-07 29.7 0.0 4.2 4 0 0 4 4 4 3 PPR repeat Fungal_trans PF04082.18 KPA42523.1 - 4.5e-13 48.9 0.4 8.6e-13 47.9 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PPR_3 PF13812.6 KPA42523.1 - 5.3e-08 32.8 0.0 0.0015 18.6 0.0 3.7 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 KPA42523.1 - 1.4e-07 31.3 0.2 0.025 14.8 0.0 5.3 5 0 0 5 5 5 2 PPR repeat Zn_clus PF00172.18 KPA42523.1 - 2.8e-06 27.4 10.7 5e-06 26.5 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.6 KPA42524.1 - 3.1e-13 49.2 15.4 1.4e-07 31.2 1.3 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KPA42524.1 - 6e-12 44.8 17.4 7.6e-07 28.6 1.8 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KPA42524.1 - 3.7e-09 36.7 0.2 7.2e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.18 KPA42524.1 - 4.6e-09 36.2 8.1 1.1e-08 35.1 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_11 PF13720.6 KPA42524.1 - 0.096 13.2 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 SANT_DAMP1_like PF16282.5 KPA42525.1 - 7.5e-31 106.2 0.4 1.7e-30 105.0 0.4 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 EMP24_GP25L PF01105.24 KPA42526.1 - 1.4e-51 175.0 0.0 1.6e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.25 KPA42527.1 - 4e-27 95.2 0.0 5.7e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA42527.1 - 1.1e-13 51.0 0.0 1.5e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPA42527.1 - 4.8e-07 28.9 0.0 7.4e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Peptidase_M44 PF03410.13 KPA42527.1 - 0.19 10.3 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox NMO PF03060.15 KPA42528.1 - 8.5e-34 117.4 1.5 9.3e-33 114.0 1.5 2.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KPA42528.1 - 3e-10 39.6 0.0 4.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KPA42528.1 - 4.4e-07 29.2 0.4 6.3e-07 28.7 0.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KPA42528.1 - 0.00019 20.7 0.2 0.00029 20.1 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase SCP2 PF02036.17 KPA42529.1 - 4.5e-24 84.9 0.3 5.2e-24 84.7 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KPA42529.1 - 0.0001 22.6 0.2 0.00014 22.2 0.2 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KPA42529.1 - 0.022 15.1 0.0 0.035 14.5 0.0 1.3 1 1 0 1 1 1 0 Sterol carrier protein domain LETM1 PF07766.13 KPA42530.1 - 4.6e-12 45.9 1.3 1.7e-10 40.7 0.0 2.3 2 1 0 2 2 2 2 LETM1-like protein GAF_2 PF13185.6 KPA42531.1 - 2.8e-08 34.1 0.0 4.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KPA42531.1 - 0.002 18.8 0.0 0.0024 18.5 0.0 1.2 1 0 0 1 1 1 1 GAF domain C2 PF00168.30 KPA42532.1 - 3.2e-14 53.1 0.0 5.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 KPA42533.1 - 5.5e-25 85.0 8.0 1.2e-06 27.6 0.1 5.5 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 KPA42533.1 - 3.1e-22 78.8 4.6 1.1e-09 38.6 0.0 3.7 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KPA42533.1 - 3.6e-21 73.2 5.1 0.00029 20.5 0.1 5.4 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 KPA42533.1 - 4.5e-19 68.0 7.7 1.6e-08 34.2 0.0 5.2 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 KPA42533.1 - 1.2e-17 62.5 2.0 0.00018 20.9 0.1 4.6 4 0 0 4 4 4 4 EF hand ChaC PF04752.12 KPA42534.1 - 2.7e-52 177.4 0.0 3.3e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein RRM_1 PF00076.22 KPA42535.1 - 1.7e-22 79.0 0.0 2.4e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPA42535.1 - 0.0014 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif HpcH_HpaI PF03328.14 KPA42537.1 - 4e-47 160.2 0.0 8.1e-47 159.2 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KPA42537.1 - 7.6e-15 54.9 0.0 5.6e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF846 PF05832.12 KPA42538.1 - 2.8e-51 173.2 10.6 3.3e-51 173.0 10.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TctB PF07331.11 KPA42538.1 - 0.42 10.9 11.6 0.83 9.9 2.6 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4870 PF09685.10 KPA42538.1 - 2.9 8.1 13.7 0.8 9.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) VSP PF03302.13 KPA42539.1 - 0.00012 21.1 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Gram_pos_anchor PF00746.21 KPA42539.1 - 0.0056 16.6 1.3 0.011 15.6 1.3 1.5 1 0 0 1 1 1 1 LPXTG cell wall anchor motif Podoplanin PF05808.11 KPA42539.1 - 0.027 14.6 0.7 0.054 13.6 0.1 1.8 2 0 0 2 2 2 0 Podoplanin LapA_dom PF06305.11 KPA42539.1 - 0.11 12.4 0.3 0.11 12.4 0.3 2.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Svf1 PF08622.10 KPA42539.1 - 0.13 12.3 0.6 0.21 11.6 0.6 1.2 1 0 0 1 1 1 0 Svf1-like N-terminal lipocalin domain EphA2_TM PF14575.6 KPA42539.1 - 0.19 12.7 0.0 0.42 11.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF726 PF05277.12 KPA42540.1 - 1.1e-125 419.2 2.4 1.5e-125 418.7 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) CbtA PF09490.10 KPA42540.1 - 0.64 9.7 6.3 0.21 11.3 3.1 1.8 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Fcf1 PF04900.12 KPA42541.1 - 5.4e-31 106.9 0.1 8.7e-31 106.3 0.1 1.3 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.14 KPA42541.1 - 2.3 6.4 13.7 3 6.0 13.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 KPA42541.1 - 6.7 6.5 24.0 11 5.9 24.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PP2C_2 PF13672.6 KPA42542.1 - 1.2e-05 25.1 0.1 3.3e-05 23.6 0.0 1.7 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 KPA42542.1 - 0.00012 22.1 0.1 0.00046 20.2 0.1 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KPA42542.1 - 0.008 15.8 0.0 0.034 13.8 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C PH PF00169.29 KPA42543.1 - 2.3e-06 28.1 0.0 7.5e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KPA42543.1 - 0.0027 18.1 1.1 0.0039 17.5 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain Spore_coat_CotO PF14153.6 KPA42543.1 - 0.43 10.5 17.9 0.85 9.5 17.9 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DUF4407 PF14362.6 KPA42543.1 - 1.5 8.1 10.0 2.9 7.2 10.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GREB1 PF15782.5 KPA42543.1 - 6.8 3.7 13.9 11 2.9 13.9 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 KPA42544.1 - 2.4e-60 204.1 0.0 5.3e-60 203.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA42544.1 - 9.7e-27 93.9 0.0 1.7e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KPA42544.1 - 2.3e-08 34.3 0.1 8e-08 32.5 0.1 2.0 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KPA42544.1 - 0.00097 19.4 0.0 0.0035 17.6 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KPA42544.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DZR PF12773.7 KPA42545.1 - 0.043 13.9 4.1 0.11 12.5 1.7 2.5 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KPA42545.1 - 3.8 8.3 9.0 1.7 9.4 4.8 2.4 1 1 1 2 2 2 0 zinc-ribbon family DUF3795 PF12675.7 KPA42545.1 - 5.3 7.5 6.6 0.46 10.9 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3795) STT3 PF02516.14 KPA42546.1 - 3.1e-137 458.5 36.9 9.5e-132 440.4 34.9 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.12 KPA42547.1 - 5.4e-24 84.4 0.1 5.6e-24 84.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain WD40 PF00400.32 KPA42548.1 - 1.2e-08 35.4 10.0 0.33 11.9 1.0 6.6 6 1 0 6 6 6 3 WD domain, G-beta repeat Aldo_ket_red PF00248.21 KPA42549.1 - 4e-54 183.8 0.0 4.5e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Torus PF16131.5 KPA42550.1 - 0.0044 17.7 0.2 0.0095 16.6 0.2 1.5 1 0 0 1 1 1 1 Torus domain CAP_GLY PF01302.25 KPA42551.1 - 1e-19 70.3 0.1 1.8e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KPA42551.1 - 9.5e-15 54.5 7.4 0.00067 20.0 0.5 5.2 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPA42551.1 - 6.2e-12 45.1 5.3 9.5e-05 22.1 0.2 4.7 3 1 2 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 KPA42551.1 - 2.2e-05 24.0 4.5 0.34 10.4 0.0 3.6 3 1 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KPA42551.1 - 0.0002 21.1 7.0 6.4 7.1 0.0 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 KPA42551.1 - 0.55 11.0 6.7 34 5.5 0.1 5.3 7 0 0 7 7 7 0 Leucine Rich Repeat PI-PLC-X PF00388.19 KPA42554.1 - 3.2e-10 39.7 0.0 1e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain S-AdoMet_synt_C PF02773.16 KPA42556.1 - 2e-65 219.0 0.3 3.4e-65 218.2 0.0 1.5 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KPA42556.1 - 7.2e-45 152.1 0.0 1.6e-44 151.0 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KPA42556.1 - 4.1e-44 149.3 0.1 1e-43 148.0 0.1 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KPA42556.1 - 0.14 10.9 0.2 0.64 8.7 0.1 1.9 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) ATP_bind_1 PF03029.17 KPA42557.1 - 1.2e-71 241.4 0.0 3.4e-71 239.9 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KPA42557.1 - 0.0012 18.9 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 KPA42557.1 - 0.0013 18.5 0.0 0.0038 17.0 0.0 1.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Thymidylate_kin PF02223.17 KPA42557.1 - 0.0026 17.5 0.0 1.8 8.2 0.1 2.4 2 0 0 2 2 2 2 Thymidylate kinase AAA_18 PF13238.6 KPA42557.1 - 0.0057 17.2 0.1 0.026 15.1 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 KPA42557.1 - 0.0077 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KPA42557.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.27 KPA42557.1 - 0.021 14.4 0.1 5.9 6.4 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CbiA PF01656.23 KPA42557.1 - 0.023 14.8 0.0 0.026 14.6 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 KPA42557.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KPA42557.1 - 0.033 14.4 0.0 0.067 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KPA42557.1 - 0.054 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 KPA42557.1 - 0.054 12.7 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain RsgA_GTPase PF03193.16 KPA42557.1 - 0.063 13.2 0.1 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 KPA42557.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KPA42557.1 - 0.066 13.3 0.0 0.22 11.6 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KPA42557.1 - 0.1 13.0 0.1 0.54 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KPA42557.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_10 PF12846.7 KPA42557.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.29 KPA42557.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 KPA42557.1 - 0.19 10.9 0.0 0.56 9.3 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit Apq12 PF12716.7 KPA42558.1 - 3.8e-10 39.6 16.0 7.5e-10 38.6 16.0 1.5 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis RP-C_C PF11800.8 KPA42559.1 - 0.021 14.9 0.5 0.078 13.1 0.5 2.0 1 0 0 1 1 1 0 Replication protein C C-terminal region THF_DHG_CYH PF00763.23 KPA42560.1 - 1.2e-24 86.8 0.0 1.9e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KPA42560.1 - 1.2e-14 53.9 0.0 7.1e-12 44.9 0.0 2.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MFS_1 PF07690.16 KPA42561.1 - 4e-29 101.6 16.7 4e-29 101.6 16.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI-anchored PF10342.9 KPA42562.1 - 2.8e-20 72.9 1.3 6.5e-20 71.7 1.3 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family WD40 PF00400.32 KPA42563.1 - 1.7e-55 183.7 14.8 1.5e-09 38.3 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA42563.1 - 3.9e-21 75.2 0.0 5.1e-05 23.5 0.0 6.2 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPA42563.1 - 1.5e-08 34.8 0.0 0.0003 20.7 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KPA42563.1 - 1.5e-06 27.4 0.1 1.1 8.2 0.0 4.4 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KPA42563.1 - 2.9e-06 26.2 4.2 0.052 12.2 0.1 4.5 2 2 2 4 4 4 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 KPA42563.1 - 0.0002 20.5 2.3 2.9 6.9 0.2 3.9 2 1 1 4 4 4 2 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.11 KPA42563.1 - 0.00057 18.7 0.1 1.7 7.3 0.0 3.9 2 2 1 4 4 4 2 Nup133 N terminal like VID27 PF08553.10 KPA42563.1 - 0.0019 17.3 0.0 0.32 10.0 0.0 3.2 1 1 3 4 4 4 1 VID27 C-terminal WD40-like domain BBS2_Mid PF14783.6 KPA42563.1 - 0.0053 16.8 0.0 0.74 9.9 0.0 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 KPA42563.1 - 0.015 14.6 0.0 0.66 9.2 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain Frtz PF11768.8 KPA42563.1 - 0.076 11.3 0.0 0.63 8.3 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz HSP70 PF00012.20 KPA42564.1 - 0.012 13.8 0.0 0.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Hsp70 protein Cnd1 PF12717.7 KPA42564.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Caskin-tail PF16632.5 KPA42565.1 - 0.3 11.5 3.6 25 5.4 0.0 2.8 2 0 0 2 2 2 0 C-terminal region of Caskin Eisosome1 PF12757.7 KPA42565.1 - 0.78 10.0 8.0 0.7 10.2 5.5 2.0 2 0 0 2 2 2 0 Eisosome protein 1 dCMP_cyt_deam_1 PF00383.23 KPA42568.1 - 7.1e-14 51.5 0.1 8.8e-14 51.2 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KPA42568.1 - 3.4e-10 40.2 1.9 1.6e-08 34.8 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KPA42568.1 - 0.0035 17.0 2.6 0.39 10.3 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Peptidase_M42 PF05343.14 KPA42568.1 - 0.051 12.6 0.0 0.057 12.4 0.0 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Pkinase PF00069.25 KPA42569.1 - 6.4e-67 225.7 0.0 1.3e-66 224.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA42569.1 - 4.6e-36 124.4 0.0 8.3e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA42569.1 - 0.00062 19.2 0.0 0.0017 17.8 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KPA42569.1 - 0.011 15.7 0.0 0.034 14.1 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KPA42569.1 - 0.019 13.8 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KPA42569.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF1722 PF08349.11 KPA42569.1 - 0.31 11.3 1.2 1.5 9.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) zf-C2H2 PF00096.26 KPA42571.1 - 3.5e-06 27.2 17.1 0.17 12.4 0.3 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type FOXP-CC PF16159.5 KPA42571.1 - 0.0049 17.5 7.0 0.04 14.5 1.5 3.4 3 0 0 3 3 3 1 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KPA42571.1 - 0.0055 17.4 19.8 1.4 10.0 0.3 5.2 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2HE PF16278.5 KPA42571.1 - 0.013 15.9 0.7 1.5 9.3 0.1 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger TOC159_MAD PF11886.8 KPA42571.1 - 0.057 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain Aa_trans PF01490.18 KPA42572.1 - 1.2e-35 123.0 25.1 8.4e-23 80.7 12.6 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein DUF3742 PF12553.8 KPA42572.1 - 1.8 8.7 7.4 0.94 9.6 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) Methyltransf_16 PF10294.9 KPA42573.1 - 5.3e-12 45.8 0.0 8.3e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Vps39_1 PF10366.9 KPA42574.1 - 0.0055 17.0 0.1 0.056 13.7 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KPA42574.1 - 0.012 16.0 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 CASP_C PF08172.12 KPA42575.1 - 1.2e-95 319.7 0.0 1.2e-95 319.7 0.0 3.3 4 0 0 4 4 4 2 CASP C terminal betaPIX_CC PF16523.5 KPA42575.1 - 0.0018 18.1 3.2 0.0018 18.1 3.2 4.6 4 0 0 4 4 4 1 betaPIX coiled coil bZIP_2 PF07716.15 KPA42575.1 - 0.0085 16.2 3.1 0.0085 16.2 3.1 7.8 6 2 1 7 7 7 1 Basic region leucine zipper TPR_MLP1_2 PF07926.12 KPA42575.1 - 0.017 15.2 7.9 0.017 15.2 7.9 7.1 4 3 1 6 6 6 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KPA42575.1 - 0.018 15.6 7.1 0.018 15.6 7.1 6.1 2 1 3 5 5 5 0 Apg6 coiled-coil region SOGA PF11365.8 KPA42575.1 - 0.019 16.1 3.3 0.019 16.1 3.3 6.2 2 1 4 6 6 6 0 Protein SOGA Fez1 PF06818.15 KPA42575.1 - 0.035 14.6 56.8 0.19 12.2 26.3 4.3 2 1 2 4 4 4 0 Fez1 DivIC PF04977.15 KPA42575.1 - 0.035 13.9 0.7 0.035 13.9 0.7 7.8 6 4 1 7 7 7 0 Septum formation initiator SlyX PF04102.12 KPA42575.1 - 0.57 10.8 0.0 0.57 10.8 0.0 7.1 7 1 1 8 8 7 0 SlyX DUF4407 PF14362.6 KPA42575.1 - 0.64 9.3 43.8 2.6 7.3 15.8 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) Metal_resist PF13801.6 KPA42575.1 - 1.7 8.9 0.0 1.7 8.9 0.0 4.0 4 0 0 4 4 4 0 Heavy-metal resistance FlaC_arch PF05377.11 KPA42575.1 - 9.9 6.6 40.7 4.3 7.8 4.5 6.9 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) DUF3455 PF11937.8 KPA42576.1 - 1.2e-42 146.0 0.1 1.6e-42 145.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) F-box PF00646.33 KPA42577.1 - 0.021 14.7 0.1 0.077 12.9 0.1 2.0 1 0 0 1 1 1 0 F-box domain Ribosomal_L22 PF00237.19 KPA42578.1 - 4e-40 136.2 0.1 5.8e-40 135.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LTD PF00932.19 KPA42578.1 - 0.094 13.1 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 Lamin Tail Domain Fibrillarin PF01269.17 KPA42579.1 - 2.3e-99 331.1 0.0 2.8e-99 330.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KPA42579.1 - 1.1e-06 28.5 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KPA42579.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.22 KPA42580.1 - 1.9e-44 152.2 0.1 2.5e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 TypeIII_RM_meth PF12564.8 KPA42580.1 - 5.5 7.2 6.2 0.67 10.1 0.2 2.6 3 0 0 3 3 3 0 Type III restriction/modification enzyme methylation subunit C2 PF00168.30 KPA42581.1 - 2e-07 31.2 0.0 5.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain Raptor_N PF14538.6 KPA42581.1 - 1.9e-06 27.9 0.0 3.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain FAD_binding_1 PF00667.20 KPA42582.1 - 3.8e-45 154.2 0.0 5e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KPA42582.1 - 9.4e-10 39.1 0.0 3e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Nitroreductase PF00881.24 KPA42583.1 - 1.9e-15 57.4 0.1 2.2e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 Nitroreductase family ubiquitin PF00240.23 KPA42584.1 - 0.00085 19.0 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KPA42584.1 - 0.0018 18.8 0.1 0.0081 16.7 0.1 2.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain THOC2_N PF16134.5 KPA42584.1 - 6.7 5.2 5.3 13 4.3 5.3 1.4 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Peptidase_C12 PF01088.21 KPA42585.1 - 1e-70 237.8 0.0 1.3e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KPA42585.1 - 5.1e-09 35.9 0.2 1.1e-08 34.8 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Xan_ur_permease PF00860.20 KPA42586.1 - 5.6e-27 94.4 22.9 5.6e-27 94.4 22.9 2.4 2 1 0 2 2 2 1 Permease family MFS_MOT1 PF16983.5 KPA42586.1 - 0.11 12.9 16.1 0.069 13.6 3.9 2.9 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily 7tm_2 PF00002.24 KPA42588.1 - 1.3e-11 44.3 3.7 1.3e-11 44.3 3.7 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KPA42588.1 - 6.9e-10 38.5 5.8 6.9e-10 38.5 5.8 1.5 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KPA42588.1 - 4.3e-08 32.8 0.6 6e-08 32.3 0.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KPA42588.1 - 1.1e-06 28.6 9.2 2.2e-06 27.6 9.2 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.9 KPA42588.1 - 0.00023 20.6 2.1 0.00023 20.6 2.1 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Frizzled PF01534.17 KPA42588.1 - 0.0044 16.1 10.8 0.065 12.3 7.8 2.5 2 1 0 2 2 2 1 Frizzled/Smoothened family membrane region LTXXQ PF07813.12 KPA42590.1 - 0.89 10.3 4.1 1.2 9.9 0.8 2.6 3 0 0 3 3 3 0 LTXXQ motif family protein Macoilin PF09726.9 KPA42591.1 - 0.27 9.7 4.2 0.33 9.5 4.2 1.2 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 KPA42591.1 - 2.8 6.1 10.6 0.18 10.1 5.8 1.4 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) adh_short_C2 PF13561.6 KPA42592.1 - 1.9e-47 161.8 0.5 2.6e-47 161.3 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA42592.1 - 4.4e-42 143.8 0.2 7.1e-42 143.1 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPA42592.1 - 2.5e-11 43.8 0.3 3.9e-11 43.2 0.3 1.2 1 0 0 1 1 1 1 KR domain N2227 PF07942.12 KPA42593.1 - 2.5e-97 325.3 0.0 3.1e-97 325.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KPA42593.1 - 0.00023 21.1 0.0 0.00052 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA42593.1 - 0.0014 19.3 0.0 0.01 16.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA42593.1 - 0.0042 17.7 0.0 0.03 15.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain HicA_toxin PF07927.12 KPA42593.1 - 0.06 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, Methyltransf_31 PF13847.6 KPA42593.1 - 0.1 12.4 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PAC4 PF16093.5 KPA42594.1 - 3.6e-21 75.1 0.3 4.9e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 POC3_POC4 PF10448.9 KPA42594.1 - 0.037 14.0 0.0 0.044 13.8 0.0 1.3 1 1 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 HEAT_EZ PF13513.6 KPA42595.1 - 1.9e-32 111.3 6.7 1e-16 61.0 0.1 10.5 8 3 2 11 11 11 5 HEAT-like repeat HEAT PF02985.22 KPA42595.1 - 7.6e-24 81.7 18.0 0.00029 20.9 0.0 11.5 13 0 0 13 13 13 5 HEAT repeat HEAT_2 PF13646.6 KPA42595.1 - 1.3e-17 63.9 0.7 5e-06 26.8 0.0 7.2 4 3 3 7 7 7 5 HEAT repeats Cnd1 PF12717.7 KPA42595.1 - 4.1e-11 43.2 0.1 0.017 15.2 0.0 4.9 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KPA42595.1 - 4.4e-09 36.8 0.8 0.2 12.2 0.0 6.5 5 3 3 8 8 8 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KPA42595.1 - 5.5e-08 32.3 1.3 0.087 11.9 0.0 4.9 4 1 1 5 5 5 3 RNAPII transcription regulator C-terminal Arm PF00514.23 KPA42595.1 - 7.4e-08 32.2 4.6 1.3 9.2 0.0 7.1 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 KPA42595.1 - 8.4e-08 32.0 4.1 3.7e-06 26.8 0.1 5.1 6 1 0 6 6 6 1 Importin-beta N-terminal domain CLASP_N PF12348.8 KPA42595.1 - 5.2e-05 22.9 1.2 8 5.9 0.0 6.2 6 2 0 7 7 7 1 CLASP N terminal HEAT_PBS PF03130.16 KPA42595.1 - 0.00019 21.8 2.0 0.95 10.3 0.0 5.8 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat V-ATPase_H_N PF03224.14 KPA42595.1 - 0.016 14.5 1.6 0.29 10.4 0.2 3.5 3 1 1 4 4 4 0 V-ATPase subunit H TAF6_C PF07571.13 KPA42595.1 - 0.052 13.9 0.0 24 5.3 0.0 4.3 4 1 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain AAA_lid_7 PF17867.1 KPA42595.1 - 0.058 13.6 0.0 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 Midasin AAA lid domain Zn_clus PF00172.18 KPA42596.1 - 1.8e-08 34.4 11.7 2.5e-08 33.9 11.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA42596.1 - 1.3e-07 30.8 0.4 2.3e-07 30.0 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SPRY PF00622.28 KPA42597.1 - 3.7e-20 72.2 0.0 6.1e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain FixS PF03597.15 KPA42598.1 - 0.92 9.3 3.8 1.8 8.3 3.8 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Med3 PF11593.8 KPA42599.1 - 0.00057 19.2 5.5 0.00084 18.6 5.5 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Nop53 PF07767.11 KPA42599.1 - 1.3 8.3 29.2 2.1 7.6 29.2 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 KPA42599.1 - 4.7 6.9 17.8 11 5.8 17.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Exo_endo_phos PF03372.23 KPA42600.1 - 1.4e-06 28.0 0.1 2.1e-06 27.5 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GEN1_C PF18380.1 KPA42601.1 - 0.22 12.4 2.4 7.8 7.5 0.7 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain FAM176 PF14851.6 KPA42601.1 - 1.1 8.9 3.5 4.1 7.1 0.1 2.3 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 KPA42601.1 - 5.4 7.5 15.0 2.2 8.7 0.5 3.4 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AdoMet_MTase PF07757.13 KPA42602.1 - 4.7e-40 136.4 0.0 8.2e-40 135.6 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 KPA42602.1 - 0.048 13.5 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KPA42602.1 - 0.067 13.2 0.1 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain TRP PF06011.12 KPA42605.1 - 1.9e-109 366.2 12.9 2.5e-109 365.8 12.9 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KPA42605.1 - 1.8e-37 128.8 0.0 2.8e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 ML-like domain BLM_N PF16202.5 KPA42605.1 - 0.00044 19.5 2.8 0.00062 19.0 2.8 1.1 1 0 0 1 1 1 1 N-terminal region of Bloom syndrome protein CorA PF01544.18 KPA42605.1 - 0.2 10.9 2.3 3.8 6.7 0.6 2.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Tweety PF04906.13 KPA42605.1 - 0.32 9.6 2.1 0.22 10.2 0.1 1.6 2 0 0 2 2 2 0 Tweety ATP-sulfurylase PF01747.17 KPA42606.1 - 7.6e-86 287.0 0.1 1.1e-85 286.5 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KPA42606.1 - 2.7e-58 196.3 0.0 4.4e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KPA42606.1 - 2.4e-54 183.3 0.0 3.7e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 KPA42606.1 - 0.041 14.0 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Acetyltransf_11 PF13720.6 KPA42607.1 - 0.06 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 UPF0016 PF01169.19 KPA42608.1 - 7e-41 138.4 25.0 3.4e-20 72.1 10.9 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 WD40 PF00400.32 KPA42609.1 - 1.4e-21 76.3 18.2 1.2e-05 26.0 0.8 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA42609.1 - 1.9e-05 24.9 0.0 0.0055 17.0 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KPA42609.1 - 0.0034 16.0 2.6 0.22 10.0 0.0 3.4 2 1 1 4 4 4 1 Cytochrome D1 heme domain DNA_pol_phi PF04931.13 KPA42609.1 - 0.0062 14.7 25.2 0.0084 14.3 25.2 1.1 1 0 0 1 1 1 1 DNA polymerase phi PD40 PF07676.12 KPA42609.1 - 0.015 15.3 0.0 0.092 12.7 0.0 2.4 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat SDA1 PF05285.12 KPA42609.1 - 0.083 12.3 25.9 0.12 11.8 25.9 1.1 1 0 0 1 1 1 0 SDA1 eIF-3c_N PF05470.12 KPA42609.1 - 0.36 9.1 6.2 0.48 8.7 6.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.10 KPA42609.1 - 1.1 8.5 22.2 1.6 8.0 22.2 1.2 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 KPA42609.1 - 5.7 5.6 7.1 8 5.1 7.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Usp PF00582.26 KPA42609.1 - 8 7.0 7.1 17 5.9 7.1 1.6 1 0 0 1 1 1 0 Universal stress protein family Presenilin PF01080.17 KPA42609.1 - 9.1 4.9 9.7 13 4.4 9.7 1.1 1 0 0 1 1 1 0 Presenilin SecE PF00584.20 KPA42610.1 - 2.5e-15 56.1 0.0 2.8e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Coq4 PF05019.13 KPA42611.1 - 1.5e-94 315.5 0.0 2.9e-94 314.6 0.0 1.5 2 0 0 2 2 2 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 RRM_1 PF00076.22 KPA42611.1 - 0.009 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YolD PF08863.10 KPA42611.1 - 0.071 13.2 0.3 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 YolD-like protein dsDNA_bind PF01984.20 KPA42612.1 - 1.7e-41 141.0 15.6 1.9e-41 140.8 15.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain cwf18 PF08315.12 KPA42612.1 - 0.006 17.3 4.6 0.0076 16.9 4.6 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Alb1 PF09135.11 KPA42612.1 - 0.39 11.6 8.0 25 5.8 8.0 2.2 1 1 0 1 1 1 0 Alb1 SUIM_assoc PF16619.5 KPA42612.1 - 0.9 9.6 9.1 0.13 12.3 5.2 1.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 LCIB_C_CA PF18599.1 KPA42612.1 - 4.5 6.5 5.9 13 5.0 5.9 1.6 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases LMBR1 PF04791.16 KPA42612.1 - 6.3 5.6 4.6 7.7 5.3 4.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein K_channel_TID PF07941.11 KPA42612.1 - 9.9 6.7 10.1 6.1 7.4 8.1 1.7 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain ApbA_C PF08546.11 KPA42613.1 - 2.1e-15 57.1 0.0 3.8e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KPA42613.1 - 5.7e-10 39.0 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.15 KPA42614.1 - 4.7e-13 49.6 0.4 4.7e-13 49.6 0.4 2.2 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Glu-tRNAGln PF02686.15 KPA42614.1 - 0.061 13.6 1.3 0.1 12.9 0.2 1.8 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit YojJ PF10372.9 KPA42614.1 - 0.11 12.5 0.1 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus NPV_P10 PF05531.12 KPA42614.1 - 0.43 11.1 5.3 0.86 10.1 1.8 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KPA42614.1 - 0.65 8.8 11.9 2.6 6.8 9.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein tRNA-synt_2 PF00152.20 KPA42615.1 - 5.2e-84 282.0 0.0 8.5e-84 281.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF3506 PF12014.8 KPA42615.1 - 0.0017 18.4 0.2 0.003 17.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) DUF2076 PF09849.9 KPA42616.1 - 2e-08 34.6 11.5 2.4e-08 34.3 11.5 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KPA42616.1 - 2.6e-05 24.2 3.8 3.6e-05 23.8 3.8 1.2 1 0 0 1 1 1 1 CHCH domain Trypan_glycop_C PF10659.9 KPA42616.1 - 0.032 14.6 1.8 0.053 13.9 1.8 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain Glyco_hydro_44 PF12891.7 KPA42616.1 - 0.094 12.6 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Glycoside hydrolase family 44 CX9C PF16860.5 KPA42616.1 - 1.1 9.4 5.3 1.1 9.4 4.2 1.5 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF1631 PF07793.11 KPA42616.1 - 2.9 6.2 6.2 3.1 6.1 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Synthase_beta PF11421.8 KPA42616.1 - 9.9 7.0 8.4 24 5.7 8.4 1.6 1 0 0 1 1 1 0 ATP synthase F1 beta subunit UBX PF00789.20 KPA42617.1 - 4.9e-16 58.7 0.0 1.2e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 UBX domain MAP7 PF05672.11 KPA42617.1 - 0.0018 18.0 28.4 0.0035 17.0 28.4 1.4 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Thioredoxin_7 PF13899.6 KPA42617.1 - 0.074 13.2 0.0 0.64 10.2 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like Asp-B-Hydro_N PF05279.11 KPA42617.1 - 0.18 11.8 12.6 0.3 11.1 12.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SET PF00856.28 KPA42618.1 - 1.7e-08 35.0 0.0 2.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KPA42619.1 - 9.3e-11 41.6 16.6 1.9e-10 40.7 16.6 1.5 1 0 0 1 1 1 1 MYND finger Fungal_trans PF04082.18 KPA42619.1 - 0.0032 16.6 0.8 0.022 13.8 0.0 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain SlyX PF04102.12 KPA42619.1 - 0.011 16.4 0.2 0.037 14.7 0.2 1.9 1 0 0 1 1 1 0 SlyX zf-C6H2 PF15801.5 KPA42619.1 - 0.13 12.6 11.8 0.37 11.1 11.8 1.9 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SURF1 PF02104.15 KPA42620.1 - 5.2e-48 163.6 0.0 6.6e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 KPA42621.1 - 5.5e-43 145.5 0.0 1e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KPA42621.1 - 1.1e-07 32.1 0.0 1.9e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KPA42621.1 - 1.9e-07 31.5 0.0 1.9e-07 31.5 0.0 2.4 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KPA42621.1 - 0.0029 17.9 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cwf_Cwc_15 PF04889.12 KPA42621.1 - 0.073 12.8 3.0 0.15 11.8 3.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Bromo_TP PF07524.13 KPA42621.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DUF4267 PF14087.6 KPA42622.1 - 7.9e-20 71.0 2.2 9.4e-20 70.8 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) NapE PF06796.11 KPA42622.1 - 0.14 11.7 1.1 0.2 11.2 0.1 1.7 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Ras PF00071.22 KPA42623.1 - 4e-55 185.8 0.0 4.6e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA42623.1 - 1.9e-21 76.5 0.0 2.7e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA42623.1 - 1.1e-07 31.5 0.0 1.4e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 KPA42624.1 - 2.1e-13 49.9 0.2 8.3e-13 48.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KPA42625.1 - 4 7.7 5.2 1.1 9.4 0.3 2.7 3 0 0 3 3 3 0 Zinc knuckle Alpha_GJ PF03229.13 KPA42626.1 - 2.7e-05 24.7 0.7 5e-05 23.9 0.7 1.4 1 0 0 1 1 1 1 Alphavirus glycoprotein J stn_TNFRSF12A PF12191.8 KPA42626.1 - 0.0042 17.3 0.0 0.0062 16.8 0.0 1.3 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TMEM154 PF15102.6 KPA42626.1 - 0.025 14.5 1.4 0.038 13.9 1.4 1.2 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 KPA42626.1 - 0.047 12.5 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless TrbL PF04610.14 KPA42626.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein CAP59_mtransfer PF11735.8 KPA42627.1 - 1.7e-67 227.6 0.0 2.4e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Mucin PF01456.17 KPA42627.1 - 0.17 11.9 6.2 0.29 11.1 6.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein FAD_binding_7 PF03441.14 KPA42629.1 - 1.5e-40 138.8 0.9 2.2e-40 138.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KPA42629.1 - 2.7e-17 63.3 0.0 4.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase MmgE_PrpD PF03972.14 KPA42630.1 - 4.2e-149 496.8 0.0 5.3e-149 496.5 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family SH3_1 PF00018.28 KPA42630.1 - 7.1e-14 51.2 0.2 2.7e-13 49.3 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KPA42630.1 - 2.4e-10 40.1 0.1 4.3e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPA42630.1 - 5.3e-09 35.6 0.0 9.9e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CMS1 PF14617.6 KPA42631.1 - 9.6e-84 280.7 2.0 1e-83 280.5 2.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KPA42631.1 - 8.9e-09 35.4 0.0 1.4e-08 34.7 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase MT0933_antitox PF14013.6 KPA42633.1 - 0.064 13.6 8.6 0.65 10.4 6.5 2.7 2 1 0 2 2 2 0 MT0933-like antitoxin protein HTH_Tnp_Tc3_2 PF01498.18 KPA42634.1 - 3.8e-07 30.2 0.1 9.9e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 KPA42634.1 - 0.023 14.5 0.0 0.072 12.8 0.0 1.7 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_32 PF13565.6 KPA42634.1 - 0.046 14.3 3.7 1.8 9.2 0.5 2.8 1 1 1 2 2 2 0 Homeodomain-like domain bVLRF1 PF18826.1 KPA42635.1 - 3.3e-63 212.0 0.2 5.7e-63 211.2 0.2 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KPA42635.1 - 4.2e-07 30.1 0.0 1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KPA42635.1 - 0.0047 17.3 0.4 0.012 16.0 0.4 1.7 1 0 0 1 1 1 1 Ankyrin repeat Casein PF00363.18 KPA42635.1 - 0.098 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Casein CDC45 PF02724.14 KPA42635.1 - 1.4 7.1 10.1 1.3 7.2 4.3 2.2 2 0 0 2 2 2 0 CDC45-like protein RPA43_OB PF17875.1 KPA42635.1 - 2 9.1 7.5 4.5 7.9 3.3 2.9 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I CFEM PF05730.11 KPA42636.1 - 2.5e-06 27.5 1.8 2.5e-06 27.5 1.8 2.7 3 0 0 3 3 3 1 CFEM domain AMP-binding PF00501.28 KPA42637.1 - 2.7e-79 266.8 0.0 3.4e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA42637.1 - 1.2e-13 51.8 0.2 4.8e-13 49.9 0.2 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Asp PF00026.23 KPA42638.1 - 4.3e-54 184.0 0.0 5.8e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA42638.1 - 5.3e-10 39.8 4.8 2.1e-09 37.8 0.6 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPA42638.1 - 0.00073 20.1 0.0 7.4 7.3 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KPA42638.1 - 0.017 15.7 0.0 55 4.4 0.0 3.6 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease ATP12 PF07542.11 KPA42639.1 - 6.9e-42 142.6 0.0 1.5e-41 141.5 0.0 1.6 1 0 0 1 1 1 1 ATP12 chaperone protein Adaptin_N PF01602.20 KPA42640.1 - 2.5e-115 386.0 1.4 3.2e-115 385.6 1.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KPA42640.1 - 3.7e-56 189.5 4.0 7.9e-56 188.4 4.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KPA42640.1 - 1.7e-36 124.9 0.1 5.3e-36 123.3 0.1 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KPA42640.1 - 1.6e-16 60.4 3.1 1.1e-11 45.0 0.1 5.0 3 1 2 5 5 5 1 HEAT repeats Cnd1 PF12717.7 KPA42640.1 - 1.6e-06 28.3 11.2 0.047 13.7 0.1 5.1 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KPA42640.1 - 0.012 15.2 0.1 0.012 15.2 0.1 3.2 4 0 0 4 4 4 0 CLASP N terminal DUF5010 PF16402.5 KPA42640.1 - 0.016 14.0 0.0 0.049 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) HEAT_PBS PF03130.16 KPA42640.1 - 0.018 15.7 0.0 18 6.4 0.0 4.3 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 KPA42640.1 - 0.059 13.6 1.1 5 7.4 0.0 3.6 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 E2F_CC-MB PF16421.5 KPA42640.1 - 0.066 13.6 0.2 0.24 11.8 0.1 2.0 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain HEAT PF02985.22 KPA42640.1 - 0.18 12.1 8.7 2.3 8.7 0.2 5.2 5 0 0 5 5 5 0 HEAT repeat DUF4105 PF13387.6 KPA42641.1 - 0.025 14.2 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Peptidase_S9 PF00326.21 KPA42644.1 - 6.9e-49 166.2 0.1 1.2e-48 165.4 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 KPA42644.1 - 3.9e-41 141.0 6.3 4.2e-41 140.9 4.4 2.0 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region VHL PF01847.16 KPA42644.1 - 1.1e-11 44.4 0.1 2.6e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 VHL beta domain Peptidase_S15 PF02129.18 KPA42644.1 - 1.1e-07 31.7 0.5 0.00018 21.2 0.1 3.3 3 1 1 4 4 4 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KPA42644.1 - 4e-05 23.3 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 KPA42644.1 - 0.0022 17.7 0.1 0.0055 16.4 0.1 1.6 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 KPA42644.1 - 0.0033 17.4 0.0 0.022 14.7 0.0 2.0 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal TnpB_IS66 PF05717.13 KPA42644.1 - 0.0036 17.2 0.1 0.064 13.2 0.0 2.3 2 0 0 2 2 2 1 IS66 Orf2 like protein Hydrolase_4 PF12146.8 KPA42644.1 - 0.043 13.1 0.1 0.58 9.4 0.0 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KPA42644.1 - 0.043 13.7 0.1 3.9 7.3 0.3 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 KPA42644.1 - 0.096 11.3 0.0 4.4 5.9 0.0 2.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 KPA42644.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase FSH1 PF03959.13 KPA42644.1 - 0.12 12.1 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DnaJ PF00226.31 KPA42645.1 - 3.7e-11 43.0 0.3 2e-10 40.6 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain MFS_1 PF07690.16 KPA42646.1 - 6.5e-29 100.9 61.7 4.7e-23 81.7 35.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA42646.1 - 0.017 13.5 14.1 0.098 11.1 2.6 2.1 1 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) FAD_binding_2 PF00890.24 KPA42647.1 - 5.2e-124 414.5 3.7 6.8e-124 414.1 3.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KPA42647.1 - 6e-44 149.1 0.3 9.1e-44 148.5 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KPA42647.1 - 5.2e-06 25.9 1.1 0.0031 16.8 0.5 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA42647.1 - 9.4e-05 21.8 0.3 0.098 11.9 0.1 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KPA42647.1 - 0.00016 20.9 2.2 0.046 12.8 1.9 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KPA42647.1 - 0.0029 16.9 2.3 0.0031 16.8 0.1 2.1 3 0 0 3 3 3 1 FAD binding domain DUF600 PF04634.12 KPA42647.1 - 0.065 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF600 DAO PF01266.24 KPA42647.1 - 0.12 12.0 1.2 0.23 11.0 1.2 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA42647.1 - 0.21 10.2 0.6 0.93 8.1 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein DUF3818 PF12825.7 KPA42648.1 - 4.3e-129 430.4 7.4 6.9e-129 429.7 7.4 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KPA42648.1 - 9e-39 132.4 0.5 1.7e-38 131.6 0.5 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KPA42648.1 - 2.7e-17 62.8 1.8 1.2e-16 60.7 0.1 2.9 2 1 0 2 2 2 1 PX domain Acetyltransf_11 PF13720.6 KPA42648.1 - 3.6 8.1 4.7 14 6.2 1.8 2.9 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Sigma_reg_N PF13800.6 KPA42649.1 - 0.036 14.4 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF2721 PF11026.8 KPA42649.1 - 0.043 13.7 0.6 0.095 12.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF5383 PF17355.2 KPA42649.1 - 0.059 13.8 1.1 0.1 12.9 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Spectrin PF00435.21 KPA42649.1 - 0.091 13.3 2.9 0.12 12.9 1.2 2.0 1 1 1 2 2 2 0 Spectrin repeat NPV_P10 PF05531.12 KPA42649.1 - 1.1 9.8 4.4 41 4.7 0.0 3.2 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DHR10 PF18595.1 KPA42649.1 - 5.7 7.0 10.0 1.2 9.2 5.4 2.2 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF2730 PF10805.8 KPA42649.1 - 7.1 6.8 9.1 8.6 6.5 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF2205 PF10224.9 KPA42649.1 - 8.7 6.4 7.2 5.8 7.0 0.5 3.6 4 0 0 4 4 4 0 Short coiled-coil protein Cgr1 PF03879.14 KPA42650.1 - 9.9e-34 116.0 36.1 1.2e-33 115.8 36.1 1.0 1 0 0 1 1 1 1 Cgr1 family Silic_transp PF03842.13 KPA42650.1 - 3.6 5.8 5.1 4.2 5.6 5.1 1.2 1 0 0 1 1 1 0 Silicon transporter RR_TM4-6 PF06459.12 KPA42650.1 - 4.1 7.2 18.2 4.2 7.1 18.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VIR_N PF15912.5 KPA42650.1 - 9.4 5.8 8.8 10 5.6 8.8 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal HSA PF07529.13 KPA42651.1 - 0.086 13.2 0.6 0.18 12.2 0.6 1.5 1 0 0 1 1 1 0 HSA PelD_GGDEF PF16963.5 KPA42652.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 PelD GGDEF domain DUF1258 PF06869.12 KPA42652.1 - 0.14 11.6 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Fungal_trans PF04082.18 KPA42654.1 - 7.9e-09 34.9 0.1 1.2e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA42654.1 - 4.5e-07 29.9 8.6 8.4e-07 29.0 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KPA42655.1 - 7.8e-21 74.0 0.6 4.6e-05 24.1 0.4 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA42655.1 - 3.1e-08 33.8 0.0 0.0087 16.3 0.0 4.8 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KPA42655.1 - 0.00031 20.4 2.2 0.00052 19.7 1.2 1.9 2 1 0 2 2 2 1 PQQ-like domain Kelch_2 PF07646.15 KPA42655.1 - 0.1 12.6 0.1 0.39 10.8 0.1 2.1 1 0 0 1 1 1 0 Kelch motif Glyco_transf_15 PF01793.16 KPA42656.1 - 9.8e-113 376.7 9.3 1.2e-112 376.4 9.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GCP_N_terminal PF17681.1 KPA42657.1 - 2.9e-41 142.1 0.0 6.2e-41 141.0 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KPA42657.1 - 6.2e-28 98.1 0.9 1.4e-27 97.0 0.9 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KPA42657.1 - 5.9e-10 38.1 0.2 8.6e-10 37.6 0.2 1.3 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Abhydrolase_2 PF02230.16 KPA42658.1 - 3.6e-13 49.8 0.0 8.9e-13 48.5 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase LCCL PF03815.19 KPA42659.1 - 6.7e-20 71.0 0.2 1.2e-19 70.2 0.2 1.3 1 0 0 1 1 1 1 LCCL domain Peptidase_U4 PF03419.13 KPA42659.1 - 0.11 11.7 4.9 0.2 10.9 4.9 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA TGT PF01702.18 KPA42660.1 - 4.1e-61 207.1 0.0 5e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Alk_phosphatase PF00245.20 KPA42661.1 - 5e-71 239.8 0.0 1.3e-70 238.5 0.0 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 KPA42661.1 - 7.7e-06 25.7 0.1 1.4e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KPA42661.1 - 2.2e-05 24.0 0.1 4.6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KPA42661.1 - 0.0011 17.7 0.5 0.0021 16.8 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF229) CutC PF03932.14 KPA42662.1 - 2.9e-17 62.8 0.0 6.5e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 CutC family NAP PF00956.18 KPA42663.1 - 1.1e-27 96.9 9.9 6.1e-27 94.5 5.7 2.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) BUD22 PF09073.10 KPA42663.1 - 0.12 11.7 10.0 0.16 11.3 10.0 1.1 1 0 0 1 1 1 0 BUD22 DUF3246 PF11596.8 KPA42663.1 - 2.3 7.6 5.2 3.6 7.0 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Questin_oxidase PF14027.6 KPA42664.1 - 9.4e-12 45.1 0.1 1.2e-11 44.8 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like WD40 PF00400.32 KPA42665.1 - 7.6e-37 124.7 31.9 1.2e-08 35.4 0.1 11.9 15 0 0 15 15 13 7 WD domain, G-beta repeat Utp12 PF04003.12 KPA42665.1 - 2.5e-24 85.6 0.0 4.1e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KPA42665.1 - 1.9e-19 69.7 0.0 0.017 15.4 0.0 10.1 6 2 5 12 12 11 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPA42665.1 - 1.2e-06 28.5 2.2 0.062 13.2 0.1 5.5 5 1 1 6 6 6 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KPA42665.1 - 2e-06 27.0 2.2 2.9 6.8 0.0 5.9 3 2 3 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KPA42665.1 - 0.00069 19.0 0.1 8 5.7 0.0 4.2 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KPA42665.1 - 0.0018 17.6 0.0 0.35 10.2 0.0 3.5 4 0 0 4 4 4 1 WD40-like domain Nup160 PF11715.8 KPA42665.1 - 0.022 13.4 3.4 14 4.2 0.0 3.9 3 2 1 4 4 4 0 Nucleoporin Nup120/160 Utp13 PF08625.11 KPA42665.1 - 0.09 12.7 0.3 0.31 10.9 0.2 2.0 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain PALB2_WD40 PF16756.5 KPA42665.1 - 0.093 11.6 0.0 5.6 5.8 0.0 2.9 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain RPN1_RPN2_N PF17781.1 KPA42665.1 - 0.18 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain PD40 PF07676.12 KPA42665.1 - 0.21 11.6 1.9 32 4.6 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Septin PF00735.18 KPA42666.1 - 5.6e-115 383.4 0.5 9e-115 382.8 0.5 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KPA42666.1 - 1.7e-07 31.3 0.0 4.2e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA42666.1 - 3.8e-06 26.9 1.6 1.9e-05 24.7 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KPA42666.1 - 1.3e-05 24.8 5.7 9.4e-05 22.0 0.1 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KPA42666.1 - 0.0015 18.9 1.5 0.0034 17.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 KPA42666.1 - 0.0033 17.6 0.1 0.0078 16.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 KPA42666.1 - 0.0034 16.9 0.1 0.0078 15.7 0.1 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein ABC_tran PF00005.27 KPA42666.1 - 0.0086 16.6 0.5 0.087 13.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter KAP_NTPase PF07693.14 KPA42666.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain AAA_25 PF13481.6 KPA42666.1 - 0.012 15.2 0.2 0.062 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPA42666.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 KPA42666.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 KPA42666.1 - 0.015 14.6 0.0 0.015 14.6 0.0 1.6 2 0 0 2 2 1 0 AIG1 family Ras PF00071.22 KPA42666.1 - 0.016 14.8 0.8 0.062 12.9 0.5 2.1 2 1 0 2 2 2 0 Ras family Casc1_N PF15927.5 KPA42666.1 - 0.025 14.3 11.7 0.066 12.9 11.7 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA_16 PF13191.6 KPA42666.1 - 0.027 14.9 1.5 0.062 13.7 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KPA42666.1 - 0.046 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 KPA42666.1 - 0.066 12.3 0.5 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein FOXP-CC PF16159.5 KPA42666.1 - 0.082 13.6 1.0 0.082 13.6 1.0 2.8 2 1 1 3 3 2 0 FOXP coiled-coil domain RNA_helicase PF00910.22 KPA42666.1 - 0.13 12.6 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Dynamin_N PF00350.23 KPA42666.1 - 0.52 10.3 7.6 4.2 7.4 0.1 3.2 2 1 1 3 3 3 0 Dynamin family Ribosomal_L6e PF01159.19 KPA42666.1 - 1.5 9.3 7.0 7.8 7.1 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e AAA_11 PF13086.6 KPA42666.1 - 1.7 8.3 7.1 17 5.1 3.6 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KPA42666.1 - 2 8.2 4.8 8.3 6.2 0.1 2.9 3 1 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation FUSC PF04632.12 KPA42666.1 - 2.5 6.5 4.5 3.3 6.1 4.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family BCDHK_Adom3 PF10436.9 KPA42667.1 - 3.9e-45 153.6 0.6 7e-45 152.8 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KPA42667.1 - 3.7e-07 30.6 0.0 2.7e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KPA42667.1 - 0.0099 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.8 KPA42668.1 - 1e-86 290.2 0.7 1e-85 286.9 0.1 2.7 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KPA42668.1 - 1.8e-75 253.2 2.0 1.8e-72 243.3 1.0 3.5 3 1 1 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KPA42668.1 - 4.1e-46 157.6 2.8 7.3e-46 156.7 2.8 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPA42668.1 - 7.8e-20 71.7 0.1 1.8e-19 70.5 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KPA42668.1 - 4.8e-11 42.8 0.0 2.7e-10 40.4 0.0 2.4 1 1 0 1 1 1 1 MATH domain YukD PF08817.10 KPA42668.1 - 0.0014 19.3 0.0 2.8 8.7 0.0 3.4 3 0 0 3 3 3 2 WXG100 protein secretion system (Wss), protein YukD ABC2_membrane PF01061.24 KPA42669.1 - 4e-83 278.0 57.0 1.7e-43 148.5 15.5 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KPA42669.1 - 3.3e-36 124.8 0.1 3.3e-18 66.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KPA42669.1 - 2.1e-29 101.3 2.0 4.9e-26 90.5 0.0 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KPA42669.1 - 3.5e-15 56.4 3.3 3.5e-15 56.4 3.3 2.6 2 1 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KPA42669.1 - 3.1e-08 33.1 28.0 0.00011 21.5 10.1 2.9 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 KPA42669.1 - 5.6e-06 26.9 0.0 0.00036 21.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KPA42669.1 - 9.5e-06 25.6 0.1 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KPA42669.1 - 1.3e-05 25.1 0.1 0.00081 19.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KPA42669.1 - 0.00013 22.0 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KPA42669.1 - 0.00028 21.3 0.1 0.025 15.0 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KPA42669.1 - 0.00046 19.9 0.3 0.67 9.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KPA42669.1 - 0.0006 20.1 0.1 0.0077 16.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KPA42669.1 - 0.005 17.1 0.0 1.1 9.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KPA42669.1 - 0.0076 15.9 0.1 0.2 11.2 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 KPA42669.1 - 0.0099 15.3 0.7 0.15 11.4 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KPA42669.1 - 0.024 14.8 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KPA42669.1 - 0.025 14.3 0.4 4.9 6.8 0.2 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KPA42669.1 - 0.084 12.0 0.5 2.3 7.3 0.2 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 KPA42669.1 - 0.098 12.4 0.3 1.6 8.4 0.1 2.7 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KPA42669.1 - 0.14 12.1 0.1 3.5 7.5 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KPA42669.1 - 0.19 11.3 0.5 2 8.0 0.1 2.4 3 0 0 3 3 2 0 AAA domain F-box-like PF12937.7 KPA42671.1 - 0.0041 17.0 0.4 0.0069 16.3 0.4 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA42671.1 - 0.021 14.7 1.1 0.034 14.0 1.1 1.4 1 0 0 1 1 1 0 F-box domain AAA_18 PF13238.6 KPA42672.1 - 2.5e-05 24.8 0.0 3.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA42672.1 - 0.00064 20.1 0.0 0.00082 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KPA42672.1 - 0.0032 17.6 0.0 0.004 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPA42672.1 - 0.0038 17.0 0.0 0.0062 16.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 KPA42672.1 - 0.015 14.3 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KPA42672.1 - 0.045 13.7 0.0 0.068 13.1 0.0 1.3 1 1 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.10 KPA42672.1 - 0.045 13.2 0.0 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 KPA42672.1 - 0.063 13.8 0.0 0.07 13.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KPA42672.1 - 0.099 12.9 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KPA42672.1 - 0.13 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 KPA42672.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase CPT PF07931.12 KPA42672.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 KPA42672.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Med5 PF08689.10 KPA42673.1 - 1e-88 298.5 0.0 2.3e-87 294.0 0.0 2.7 1 1 0 1 1 1 1 Mediator complex subunit Med5 Ric8 PF10165.9 KPA42673.1 - 0.046 12.8 0.9 4.6 6.2 0.1 2.8 2 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn Connexin PF00029.19 KPA42673.1 - 0.18 11.5 0.3 0.31 10.8 0.3 1.3 1 0 0 1 1 1 0 Connexin Pyr_redox_2 PF07992.14 KPA42674.1 - 5e-29 101.5 0.1 6.2e-29 101.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA42674.1 - 1.1e-07 32.3 0.1 5.2e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HisG PF01634.18 KPA42675.1 - 1.1e-55 188.0 0.0 2e-55 187.1 0.0 1.5 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KPA42675.1 - 3.4e-28 97.6 0.1 7.1e-28 96.6 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KPA42675.1 - 0.0038 17.2 0.0 0.077 12.9 0.0 2.4 2 1 0 2 2 2 1 NMT1/THI5 like Abhydrolase_9_N PF15420.6 KPA42676.1 - 0.016 15.2 1.4 0.18 11.8 0.8 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus FAM199X PF15814.5 KPA42677.1 - 1.5 7.8 6.6 1.7 7.7 6.6 1.0 1 0 0 1 1 1 0 Protein family FAM199X Ion_trans PF00520.31 KPA42678.1 - 7.1e-118 392.2 92.4 5.6e-43 146.9 9.1 4.7 4 1 0 4 4 4 4 Ion transport protein SOR_SNZ PF01680.17 KPA42678.1 - 0.14 11.9 0.8 0.24 11.2 0.8 1.2 1 0 0 1 1 1 0 SOR/SNZ family PHD PF00628.29 KPA42679.1 - 1.4e-08 34.5 7.2 3e-08 33.4 7.2 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KPA42679.1 - 0.21 11.2 4.7 0.42 10.2 4.7 1.5 1 0 0 1 1 1 0 PHD-finger HMG_box PF00505.19 KPA42680.1 - 4.5e-14 52.6 0.7 1.7e-13 50.8 0.3 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KPA42680.1 - 1.9e-06 28.4 0.4 4.5e-06 27.2 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KPA42680.1 - 0.019 14.3 0.2 0.03 13.6 0.2 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box NOG1_N PF17835.1 KPA42680.1 - 0.13 12.2 0.2 0.21 11.5 0.2 1.2 1 0 0 1 1 1 0 NOG1 N-terminal helical domain Macoilin PF09726.9 KPA42681.1 - 6.8 5.1 20.9 1.9 6.9 8.1 2.1 2 0 0 2 2 2 0 Macoilin family F1F0-ATPsyn_F PF10791.9 KPA42682.1 - 3.2e-41 139.7 0.2 3.6e-41 139.5 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi ETC_C1_NDUFA4 PF04800.12 KPA42683.1 - 4.6e-36 122.9 1.4 7.7e-36 122.2 1.4 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region CLTH PF10607.9 KPA42684.1 - 9e-33 113.3 0.0 1.2e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KPA42684.1 - 8.6e-08 31.9 0.5 1.6e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 LisH PRK PF00485.18 KPA42685.1 - 3.6e-59 199.8 0.0 5.1e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KPA42685.1 - 4.6e-42 143.8 0.0 6.6e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_33 PF13671.6 KPA42685.1 - 1.9e-06 28.1 0.0 5.5e-05 23.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KPA42685.1 - 3.6e-06 27.6 0.0 7.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KPA42685.1 - 6.9e-06 26.0 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KPA42685.1 - 5e-05 22.7 0.0 0.00023 20.5 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.6 KPA42685.1 - 7.5e-05 23.2 3.5 0.0026 18.2 0.5 3.2 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KPA42685.1 - 0.008 16.7 0.0 0.021 15.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 KPA42685.1 - 0.011 15.0 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Cytidylate_kin PF02224.18 KPA42685.1 - 0.028 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase MMR_HSR1 PF01926.23 KPA42685.1 - 0.035 14.2 0.0 0.094 12.8 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KPA42685.1 - 0.044 13.5 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KPA42685.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Glyco_trans_4_4 PF13579.6 KPA42685.1 - 0.12 12.8 0.2 0.43 11.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain dNK PF01712.19 KPA42685.1 - 0.13 12.1 0.1 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_5 PF07728.14 KPA42685.1 - 0.14 12.2 0.0 0.58 10.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KPA42685.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KPA42685.1 - 0.17 12.2 0.0 0.49 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Pyr_redox_2 PF07992.14 KPA42686.1 - 3.6e-43 147.9 0.0 1e-42 146.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA42686.1 - 4.4e-12 46.4 0.4 4.6e-08 33.5 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KPA42686.1 - 5.4e-08 31.8 0.6 1.2e-07 30.8 0.6 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KPA42686.1 - 6e-07 28.9 1.0 1.8e-06 27.4 1.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KPA42686.1 - 6.6e-05 22.2 1.6 0.00014 21.1 1.6 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KPA42686.1 - 9.6e-05 22.8 0.1 0.00029 21.2 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KPA42686.1 - 0.0042 16.9 0.1 0.0095 15.8 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair NAD_binding_8 PF13450.6 KPA42686.1 - 0.1 12.8 0.1 3.5 7.9 0.0 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Nop53 PF07767.11 KPA42687.1 - 4.5e-111 372.1 39.4 5.1e-111 371.9 39.4 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Ras PF00071.22 KPA42688.1 - 7.5e-60 201.2 0.5 9.9e-60 200.8 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA42688.1 - 1.4e-37 128.6 0.1 2.5e-37 127.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA42688.1 - 1.2e-18 67.2 0.3 1.5e-18 66.8 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPA42688.1 - 7.8e-07 28.8 0.1 8.9e-06 25.4 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KPA42688.1 - 7.8e-06 25.4 0.1 1.3e-05 24.8 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPA42688.1 - 1.3e-05 25.2 0.1 3.3e-05 23.9 0.1 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KPA42688.1 - 1.9e-05 24.2 0.5 2.4e-05 23.8 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KPA42688.1 - 0.00011 22.2 0.1 0.065 13.1 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 KPA42688.1 - 0.0044 16.8 0.2 0.012 15.4 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FlgH PF02107.16 KPA42688.1 - 0.034 13.8 1.5 0.049 13.2 1.5 1.3 1 0 0 1 1 1 0 Flagellar L-ring protein TIR_2 PF13676.6 KPA42688.1 - 0.047 14.3 0.1 0.097 13.3 0.1 1.5 1 0 0 1 1 1 0 TIR domain AAA_28 PF13521.6 KPA42688.1 - 0.084 13.1 0.1 16 5.7 0.0 2.3 1 1 0 2 2 2 0 AAA domain Rib_5-P_isom_A PF06026.14 KPA42689.1 - 7.1e-44 149.4 0.0 1.4e-43 148.5 0.0 1.5 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Kei1 PF08552.11 KPA42690.1 - 1.9e-56 191.0 10.9 1.3e-55 188.3 10.9 1.9 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Na_Ca_ex PF01699.24 KPA42690.1 - 0.39 10.7 6.6 0.062 13.3 2.0 2.0 2 0 0 2 2 2 0 Sodium/calcium exchanger protein SPC12 PF06645.13 KPA42690.1 - 1.8 8.7 7.4 0.17 12.0 1.9 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) NIR_SIR PF01077.22 KPA42691.1 - 2.5e-54 183.1 0.0 6.3e-50 168.8 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KPA42691.1 - 3.3e-30 103.7 0.0 7.1e-14 51.4 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KPA42691.1 - 2.2e-28 99.2 0.0 4.6e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 KPA42691.1 - 5.4e-05 23.0 0.3 0.00013 21.8 0.1 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 KPA42691.1 - 0.0022 18.2 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Chitin_synth_1 PF01644.17 KPA42692.1 - 1.3e-77 259.4 0.1 3e-77 258.2 0.1 1.7 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.11 KPA42692.1 - 2.8e-27 94.5 0.2 5.5e-27 93.5 0.2 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KPA42692.1 - 3.4e-24 85.4 7.3 6.4e-21 74.6 0.1 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KPA42692.1 - 1.2e-08 35.2 1.3 3.5e-08 33.6 1.3 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Amidohydro_3 PF07969.11 KPA42693.1 - 1.4e-11 44.5 0.4 6.2e-09 35.8 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KPA42693.1 - 9.8e-10 38.3 0.1 4.5e-08 32.8 0.0 3.1 3 0 0 3 3 3 1 Amidohydrolase family MAAL_N PF05034.13 KPA42693.1 - 0.056 13.1 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase N-terminus LigB PF02900.18 KPA42694.1 - 3.7e-35 121.3 0.0 6.7e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase GATase PF00117.28 KPA42694.1 - 1.7e-06 27.9 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Pkinase PF00069.25 KPA42695.1 - 1.7e-19 70.2 0.0 2.2e-13 50.2 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA42695.1 - 4e-05 23.0 1.1 0.0015 17.9 0.1 2.9 3 1 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.14 KPA42695.1 - 0.00041 19.8 0.0 0.00084 18.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPA42695.1 - 0.0088 16.0 0.1 0.018 15.0 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KPA42695.1 - 0.018 14.3 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Kinase-like LDB19 PF13002.7 KPA42696.1 - 2.7e-37 128.3 0.4 4.4e-37 127.7 0.4 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KPA42696.1 - 0.00023 21.2 0.0 0.00051 20.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain FlxA PF14282.6 KPA42697.1 - 0.0033 17.4 1.5 0.0033 17.4 1.5 2.8 1 1 1 2 2 2 1 FlxA-like protein Remorin_C PF03763.13 KPA42697.1 - 0.0037 17.1 2.7 0.0037 17.1 2.7 1.8 2 0 0 2 2 2 1 Remorin, C-terminal region DUF3080 PF11279.8 KPA42697.1 - 0.0037 16.5 0.8 0.0081 15.4 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) DUF148 PF02520.17 KPA42697.1 - 0.0046 17.1 2.4 0.0089 16.1 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF148 GTP-bdg_M PF16360.5 KPA42697.1 - 0.047 14.3 1.1 0.25 12.0 0.2 2.7 3 1 0 3 3 2 0 GTP-binding GTPase Middle Region SHE3 PF17078.5 KPA42697.1 - 0.056 13.2 4.2 0.49 10.1 1.6 2.6 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 OmpH PF03938.14 KPA42697.1 - 0.067 13.5 8.4 0.98 9.8 0.4 2.7 2 1 1 3 3 2 0 Outer membrane protein (OmpH-like) HsbA PF12296.8 KPA42697.1 - 0.07 13.6 3.6 10 6.6 0.0 3.0 3 1 0 3 3 2 0 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 KPA42697.1 - 0.13 12.2 1.6 2.3 8.3 1.3 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAM184 PF15665.5 KPA42697.1 - 0.34 10.7 5.8 1.4 8.6 5.7 2.0 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Golgin_A5 PF09787.9 KPA42697.1 - 0.34 10.3 6.5 1.8 8.0 6.4 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 KPA42697.1 - 0.39 10.9 6.4 1.6 8.9 4.3 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KPA42697.1 - 0.41 9.9 5.1 0.79 9.0 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 KPA42697.1 - 0.51 10.6 4.5 1.2 9.4 2.9 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.18 KPA42697.1 - 0.51 9.6 4.2 0.32 10.3 2.1 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF349 PF03993.12 KPA42697.1 - 1 9.7 6.0 0.62 10.4 0.9 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) DUF1664 PF07889.12 KPA42697.1 - 1 9.4 3.4 27 4.8 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1640 PF07798.11 KPA42697.1 - 1.4 8.9 7.7 3.2 7.8 7.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.12 KPA42697.1 - 2.4 8.2 8.0 1.7 8.7 1.1 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4618 PF15397.6 KPA42697.1 - 3.3 7.1 8.3 2.2 7.6 1.3 2.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4618) Pkinase PF00069.25 KPA42698.1 - 2.4e-55 187.7 0.0 4e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA42698.1 - 2.4e-34 118.8 0.0 3.9e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA42698.1 - 4e-15 55.9 0.0 1.7e-11 43.9 0.0 2.9 1 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 KPA42698.1 - 0.0024 17.3 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 KPA42698.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 Protein-kinase domain of FAM69 Hydrolase PF00702.26 KPA42699.1 - 0.02 15.2 0.0 0.042 14.1 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1048 PF06304.11 KPA42699.1 - 0.09 13.2 0.0 0.51 10.8 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1048) Bmt2 PF11968.8 KPA42700.1 - 9.8e-85 283.9 0.0 1.4e-84 283.4 0.0 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Ribosomal_L23eN PF03939.13 KPA42701.1 - 5.9e-23 80.8 8.4 5.9e-23 80.8 8.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KPA42701.1 - 2e-15 56.9 0.2 2e-15 56.9 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.15 KPA42702.1 - 1.4e-22 79.1 1.3 1.8e-22 78.7 1.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CorA PF01544.18 KPA42703.1 - 2.3e-43 148.6 0.0 4e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.13 KPA42704.1 - 9.5e-32 108.9 0.9 1.1e-31 108.7 0.9 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ZYG-11_interact PF05884.12 KPA42704.1 - 0.0083 15.6 0.1 0.0083 15.6 0.1 1.0 1 0 0 1 1 1 1 Interactor of ZYG-11 DUF4133 PF13571.6 KPA42704.1 - 0.049 14.0 1.2 0.059 13.7 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) DUF3040 PF11239.8 KPA42704.1 - 0.094 13.0 1.6 0.12 12.6 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) zf-rbx1 PF12678.7 KPA42705.1 - 9.5e-25 86.7 12.6 1.5e-24 86.1 12.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KPA42705.1 - 3.6e-17 62.2 9.8 4.8e-17 61.8 9.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KPA42705.1 - 2.5e-06 27.7 13.8 9.5e-05 22.7 13.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPA42705.1 - 4e-05 23.4 2.7 4e-05 23.4 2.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA42705.1 - 0.0021 17.9 11.5 0.038 13.9 11.5 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPA42705.1 - 0.2 11.5 10.3 0.69 9.8 4.1 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA42705.1 - 0.29 11.2 6.9 1.1 9.4 6.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 KPA42705.1 - 0.33 10.8 16.0 29 4.5 16.0 2.5 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KPA42705.1 - 0.89 9.8 9.1 5.2 7.3 9.4 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KPA42705.1 - 1.7 8.3 14.9 2.6e+02 1.3 14.9 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type PNRC PF15365.6 KPA42706.1 - 8e-08 31.9 8.3 8e-08 31.9 8.3 4.0 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif 4PPT_N PF17837.1 KPA42706.1 - 0.018 15.2 0.4 0.037 14.2 0.4 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Aa_trans PF01490.18 KPA42707.1 - 1.2e-62 212.0 26.9 1.5e-62 211.6 26.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KPA42707.1 - 0.00042 19.5 8.4 0.00042 19.5 8.4 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family ZnuA PF01297.17 KPA42708.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic WD40 PF00400.32 KPA42709.1 - 1.1e-59 197.0 15.3 9.3e-09 35.8 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KPA42709.1 - 6.4e-17 61.6 8.5 1.2e-16 60.8 8.5 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KPA42709.1 - 2.2e-16 59.9 0.0 0.00017 21.9 0.0 6.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA42709.1 - 2.9e-06 26.5 0.3 0.52 9.2 0.0 4.9 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KPA42709.1 - 3.9e-06 26.4 0.0 0.37 10.1 0.0 4.7 3 2 2 5 5 5 2 WD40-like domain Nup160 PF11715.8 KPA42709.1 - 0.0028 16.4 1.2 0.46 9.1 0.0 3.4 2 1 2 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KPA42709.1 - 0.013 14.2 0.1 8 5.1 0.0 3.6 2 1 1 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 KPA42709.1 - 0.056 12.0 0.1 1.7 7.1 0.1 2.8 2 1 2 4 4 4 0 Cytochrome D1 heme domain MMS1_N PF10433.9 KPA42709.1 - 0.065 11.9 0.0 0.48 9.0 0.0 2.0 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Golgin_A5 PF09787.9 KPA42709.1 - 0.086 12.3 4.1 0.13 11.7 4.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Tektin PF03148.14 KPA42709.1 - 0.31 9.7 4.1 0.42 9.3 4.1 1.1 1 0 0 1 1 1 0 Tektin family FA_hydroxylase PF04116.13 KPA42710.1 - 2.5e-24 86.1 17.3 2.5e-24 86.1 17.3 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Babuvirus_MP PF07234.11 KPA42710.1 - 0.25 11.5 0.9 0.48 10.6 0.9 1.4 1 0 0 1 1 1 0 Movement and RNA silencing protein HTH_33 PF13592.6 KPA42710.1 - 0.36 10.5 2.6 6.7 6.4 1.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix DUF2015 PF09435.10 KPA42711.1 - 1.2e-47 160.4 0.0 1.3e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 KPA42712.1 - 1.8e-34 118.9 3.6 2.6e-34 118.4 3.6 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family MRP-S31 PF15433.6 KPA42712.1 - 0.28 10.8 4.5 0.42 10.2 4.5 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Ldh_1_C PF02866.18 KPA42713.1 - 6.7e-45 153.0 0.0 9.7e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KPA42713.1 - 2.1e-42 144.6 0.1 3e-42 144.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KPA42713.1 - 0.0049 15.9 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KPA42713.1 - 0.02 15.3 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TRAPP PF04051.16 KPA42714.1 - 1.9e-46 157.4 0.0 2.9e-46 156.8 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component GARS_A PF01071.19 KPA42715.1 - 1.5e-82 276.1 0.0 2.4e-82 275.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KPA42715.1 - 2.7e-35 121.0 0.2 3.2e-34 117.6 0.0 2.8 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KPA42715.1 - 6e-34 117.4 0.0 1.8e-33 115.9 0.0 1.8 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KPA42715.1 - 4.6e-28 97.3 0.6 9.5e-27 93.1 0.2 2.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KPA42715.1 - 4e-15 56.2 1.5 1.2e-14 54.7 1.5 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 KPA42715.1 - 0.0012 18.4 0.1 0.0022 17.5 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 KPA42715.1 - 0.0044 16.6 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KPA42715.1 - 0.0056 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KPA42715.1 - 0.029 14.0 0.1 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KPA42715.1 - 0.046 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.10 KPA42715.1 - 0.13 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain PINIT PF14324.6 KPA42716.1 - 7.5e-42 143.1 0.1 1.6e-41 142.1 0.1 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KPA42716.1 - 2.3e-22 78.5 5.3 5.3e-22 77.3 5.3 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KPA42716.1 - 1.4e-05 24.8 0.8 6.2e-05 22.7 0.7 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.15 KPA42716.1 - 0.015 15.4 0.1 0.039 14.0 0.1 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Herpes_UL49_1 PF03117.14 KPA42716.1 - 0.044 13.1 0.5 0.068 12.4 0.5 1.3 1 0 0 1 1 1 0 UL49 family Prok-RING_4 PF14447.6 KPA42716.1 - 0.38 10.7 2.5 0.88 9.5 2.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TFIIF_alpha PF05793.12 KPA42716.1 - 0.62 8.6 4.0 0.87 8.1 4.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-C3HC4_4 PF15227.6 KPA42716.1 - 1.4 9.1 4.4 3.1 8.0 4.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2423 PF10338.9 KPA42717.1 - 6.7e-19 67.8 5.3 6.7e-19 67.8 5.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Spore_coat_CotO PF14153.6 KPA42717.1 - 0.16 11.9 8.9 0.18 11.7 8.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO MRNIP PF15749.5 KPA42717.1 - 0.38 11.5 6.3 0.55 11.0 6.3 1.4 1 1 0 1 1 1 0 MRN-interacting protein Phosphodiest PF01663.22 KPA42718.1 - 3.3e-14 53.3 1.3 1.4e-10 41.4 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KPA42718.1 - 9.1e-06 25.3 0.0 2.2e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Sulfatase DUF229 PF02995.17 KPA42718.1 - 0.044 12.4 0.0 0.066 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Cnd3 PF12719.7 KPA42719.1 - 1.2e-93 313.5 4.4 1.3e-93 313.5 3.0 1.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KPA42719.1 - 3.4e-10 40.2 12.4 3.7e-05 24.0 3.2 5.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KPA42719.1 - 0.00014 21.8 14.0 0.078 13.3 0.0 6.9 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 KPA42719.1 - 0.003 17.6 8.6 0.037 14.1 0.1 5.1 4 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 FANCI_HD1 PF14679.6 KPA42719.1 - 0.019 14.9 0.2 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 FANCI helical domain 1 Vac14_Fab1_bd PF12755.7 KPA42719.1 - 0.13 12.8 0.0 3.8 8.2 0.0 3.1 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KPA42719.1 - 0.27 9.8 4.3 2.2 6.7 0.0 2.8 3 0 0 3 3 3 0 Adaptin N terminal region HEAT_EZ PF13513.6 KPA42719.1 - 6.4 7.4 5.8 14 6.3 0.1 4.6 4 1 1 5 5 5 0 HEAT-like repeat RRM_1 PF00076.22 KPA42720.1 - 1.1e-57 191.7 0.0 6.9e-17 61.0 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KPA42720.1 - 2.7e-07 31.0 0.7 5 7.3 0.0 7.2 5 3 2 8 8 8 2 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 KPA42720.1 - 1.6e-06 28.0 0.1 0.23 11.2 0.1 3.8 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KPA42720.1 - 0.0029 17.7 0.2 6.3 7.0 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif Mg_trans_NIPA PF05653.14 KPA42722.1 - 5.2e-60 203.0 6.8 2.9e-57 194.1 4.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KPA42722.1 - 0.0027 17.9 26.1 0.03 14.5 0.9 4.1 3 1 1 4 4 4 3 EamA-like transporter family DUF5362 PF17319.2 KPA42722.1 - 0.04 13.8 0.8 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5362) GRP PF07172.11 KPA42722.1 - 0.045 14.4 5.8 0.15 12.8 4.8 2.3 2 0 0 2 2 2 0 Glycine rich protein family BaxI_1 PF12811.7 KPA42722.1 - 0.097 12.2 9.7 0.21 11.1 9.6 1.6 1 1 0 1 1 1 0 Bax inhibitor 1 like TssN PF17555.2 KPA42722.1 - 0.26 10.6 7.2 0.57 9.5 7.2 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssN MerC PF03203.14 KPA42722.1 - 0.27 11.7 11.2 0.47 10.9 1.4 3.3 2 1 2 4 4 3 0 MerC mercury resistance protein DUF2569 PF10754.9 KPA42722.1 - 0.3 11.5 7.1 0.1 13.0 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) CPP1-like PF11833.8 KPA42722.1 - 0.62 9.7 3.0 1.8 8.2 2.9 1.8 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF4231 PF14015.6 KPA42722.1 - 1.2 9.6 4.5 20 5.7 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) DUF1461 PF07314.11 KPA42722.1 - 1.3 8.9 5.7 0.9 9.4 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF4131 PF13567.6 KPA42722.1 - 1.7 8.3 8.7 2.5 7.7 0.3 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4131) LysE PF01810.18 KPA42722.1 - 7.1 6.0 11.3 0.43 10.0 0.2 2.9 2 1 1 3 3 3 0 LysE type translocator Cutinase PF01083.22 KPA42724.1 - 8.9e-41 139.8 0.3 1.3e-40 139.2 0.3 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPA42724.1 - 7.2e-05 22.4 0.0 0.00014 21.5 0.0 1.5 1 1 0 1 1 1 1 PE-PPE domain Lipase_2 PF01674.18 KPA42724.1 - 0.042 13.4 0.0 0.06 12.9 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 2) Palm_thioest PF02089.15 KPA42724.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 Palmitoyl protein thioesterase SDH_alpha PF03313.15 KPA42724.1 - 0.066 12.9 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain Sec6 PF06046.13 KPA42724.1 - 0.11 10.8 0.1 0.15 10.4 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 CPW_WPC PF09717.10 KPA42726.1 - 0.016 16.2 0.3 1.5 9.9 0.1 2.4 2 0 0 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) GIY-YIG PF01541.24 KPA42727.1 - 0.17 12.2 0.5 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 GIY-YIG catalytic domain Acetyltransf_1 PF00583.25 KPA42728.1 - 2.6e-11 43.8 0.0 7e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA42728.1 - 2.9e-08 34.0 0.0 5.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA42728.1 - 2.3e-06 27.5 0.0 6.9e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA42728.1 - 2.7e-06 27.2 0.0 4.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KPA42728.1 - 0.0019 18.3 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KPA42728.1 - 0.0033 17.5 0.0 0.0075 16.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain HCV_NS5a_C PF12941.7 KPA42729.1 - 0.58 10.0 4.9 1.2 8.9 4.9 1.5 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region zf-C2H2 PF00096.26 KPA42730.1 - 4.4 7.9 10.9 5.3 7.7 0.7 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 KPA42731.1 - 0.023 15.1 6.5 0.37 11.3 1.6 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KPA42731.1 - 0.19 11.9 1.8 0.21 11.7 0.2 1.8 2 0 0 2 2 2 0 Aberrant zinc-finger GalKase_gal_bdg PF10509.9 KPA42732.1 - 2.5e-21 75.0 0.0 5.2e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KPA42732.1 - 3.7e-13 49.5 1.3 1e-12 48.1 1.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KPA42732.1 - 1.3e-11 44.7 0.1 3.5e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal DUF494 PF04361.13 KPA42733.1 - 0.15 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF494) Ceramidase PF05875.12 KPA42734.1 - 2e-60 204.5 10.1 2.2e-60 204.3 10.1 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 KPA42734.1 - 0.049 13.6 1.6 0.22 11.5 1.6 2.2 1 0 0 1 1 1 0 Trp-operon Leader Peptide RINGv PF12906.7 KPA42736.1 - 0.0001 22.4 8.1 0.00018 21.6 8.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KPA42736.1 - 0.013 15.8 10.1 0.022 15.1 10.1 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 KPA42736.1 - 0.029 14.5 5.3 0.053 13.7 5.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain CYSTM PF12734.7 KPA42736.1 - 0.056 13.8 0.7 0.5 10.7 0.0 2.8 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance YceG PF02618.16 KPA42736.1 - 0.26 10.8 1.6 0.39 10.2 1.6 1.2 1 0 0 1 1 1 0 YceG-like family SGTA_dimer PF16546.5 KPA42737.1 - 2e-26 91.5 1.1 3.6e-26 90.7 1.1 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KPA42737.1 - 1.3e-15 56.4 4.4 1.1e-06 28.2 1.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPA42737.1 - 3.9e-14 51.6 5.1 4.1e-05 23.4 0.6 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KPA42737.1 - 6.6e-09 35.3 4.8 0.026 14.7 0.8 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KPA42737.1 - 2.3e-08 33.6 4.5 0.00015 21.4 2.9 2.9 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 KPA42737.1 - 8.8e-07 29.2 3.9 0.069 14.0 0.4 3.8 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KPA42737.1 - 4.8e-06 27.0 5.5 0.015 15.8 0.6 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPA42737.1 - 3.2e-05 24.5 11.5 0.0072 17.0 3.9 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KPA42737.1 - 0.00029 20.9 0.5 0.0014 18.7 0.3 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KPA42737.1 - 0.00035 20.7 6.8 0.013 15.8 1.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPA42737.1 - 0.00085 19.2 1.1 0.11 12.6 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPA42737.1 - 0.00088 19.5 6.9 0.0016 18.7 2.9 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat STI1 PF17830.1 KPA42737.1 - 0.0011 18.9 8.6 0.0017 18.3 4.2 2.4 2 0 0 2 2 2 1 STI1 domain XPC-binding PF09280.11 KPA42737.1 - 0.03 14.1 0.8 0.092 12.5 0.4 1.9 2 0 0 2 2 2 0 XPC-binding domain BTAD PF03704.17 KPA42737.1 - 0.078 13.4 2.2 0.97 9.9 0.3 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KPA42737.1 - 0.17 11.8 7.8 0.87 9.6 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPA42737.1 - 0.28 11.9 4.2 0.85 10.4 0.4 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat p450 PF00067.22 KPA42738.1 - 1e-71 242.1 0.0 1.2e-71 241.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_attach PF05354.11 KPA42739.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Phage Head-Tail Attachment Trypan_PARP PF05887.11 KPA42740.1 - 0.0018 18.3 3.3 0.0038 17.2 0.2 2.2 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Nha1_C PF08619.10 KPA42741.1 - 2.8e-121 406.0 31.8 3.4e-121 405.7 31.8 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KPA42741.1 - 1.7e-74 250.9 21.5 2e-74 250.7 21.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KPA42741.1 - 1.5 9.0 8.1 0.15 12.2 0.9 2.6 3 0 0 3 3 3 0 YrhC-like protein Erythro-docking PF09277.11 KPA42742.1 - 0.11 12.4 2.0 0.4 10.6 2.0 1.9 1 0 0 1 1 1 0 Erythronolide synthase, docking UPF0227 PF05728.12 KPA42743.1 - 0.0098 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) PIG-L PF02585.17 KPA42744.1 - 1.3e-24 87.3 0.0 1.8e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Peptidase_S10 PF00450.22 KPA42745.1 - 4.5e-99 332.7 2.5 5.6e-99 332.4 2.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2461 PF09365.10 KPA42746.1 - 0.037 14.0 0.0 0.037 14.0 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) Nucleo_P87 PF07267.11 KPA42746.1 - 0.19 10.5 11.8 0.3 9.9 11.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HNF-1_N PF04814.13 KPA42746.1 - 0.27 11.8 7.2 0.46 11.1 7.2 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Hamartin PF04388.12 KPA42746.1 - 0.42 9.2 8.3 0.58 8.8 8.3 1.1 1 0 0 1 1 1 0 Hamartin protein OmpH PF03938.14 KPA42746.1 - 2.5 8.4 19.6 4.5 7.6 19.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PA26 PF04636.13 KPA42746.1 - 5.5 5.8 8.6 7.7 5.3 8.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RR_TM4-6 PF06459.12 KPA42746.1 - 6.7 6.4 11.3 11 5.8 11.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Trypsin_2 PF13365.6 KPA42747.1 - 1.1e-24 88.0 0.0 1.8e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KPA42747.1 - 0.022 14.6 0.0 0.052 13.3 0.0 1.6 1 1 0 1 1 1 0 Trypsin SAM_2 PF07647.17 KPA42748.1 - 2.9e-15 56.1 0.0 5.5e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KPA42748.1 - 6.7e-15 55.3 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KPA42748.1 - 1.8e-10 41.3 0.0 3.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 KPA42748.1 - 0.038 14.0 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Aminotran_1_2 PF00155.21 KPA42749.1 - 6.2e-59 200.0 0.0 8.9e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KPA42749.1 - 0.13 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KPA42749.1 - 0.23 10.7 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AMP-binding PF00501.28 KPA42750.1 - 3.8e-45 154.3 0.0 4.9e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KPA42750.1 - 1.9e-08 34.1 2.1 4.7e-08 32.8 0.2 2.4 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KPA42750.1 - 0.00056 20.8 0.1 0.0018 19.2 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 KPA42751.1 - 3.7e-38 128.8 19.2 3.1e-07 31.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA42751.1 - 1.7e-14 53.9 0.0 0.00025 21.3 0.1 4.9 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA42751.1 - 4.8e-06 25.8 0.1 0.44 9.5 0.0 4.0 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KPA42751.1 - 0.00016 21.6 0.0 0.25 11.2 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KPA42751.1 - 0.0053 16.1 0.0 0.3 10.4 0.0 2.8 2 1 1 3 3 3 1 WD40-like domain Phosducin PF02114.16 KPA42752.1 - 2.8e-08 33.0 0.3 2.5e-07 29.9 0.3 2.1 1 1 0 1 1 1 1 Phosducin Citrate_bind PF16114.5 KPA42752.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding Apolipoprotein PF01442.18 KPA42753.1 - 9.9e-05 22.3 3.4 0.00031 20.7 3.4 1.8 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 KPA42753.1 - 3.4 7.1 6.5 0.63 9.5 2.7 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Ran_BP1 PF00638.18 KPA42754.1 - 4.5e-49 165.8 1.9 7.7e-49 165.0 1.9 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KPA42754.1 - 0.0019 18.2 0.3 0.0086 16.0 0.3 1.9 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KPA42754.1 - 0.0032 17.7 0.1 0.0047 17.2 0.1 1.4 1 0 0 1 1 1 1 VID27 PH-like domain PS-DH PF14765.6 KPA42754.1 - 0.024 13.9 0.5 0.04 13.2 0.2 1.5 2 0 0 2 2 2 0 Polyketide synthase dehydratase PHD20L1_u1 PF16660.5 KPA42754.1 - 0.24 12.2 3.2 0.46 11.3 3.2 1.5 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 TMEM247 PF15444.6 KPA42754.1 - 3.6 7.6 6.8 5.5 7.0 6.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 CDC27 PF09507.10 KPA42754.1 - 4.6 6.5 26.7 0.18 11.1 20.9 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 YEATS PF03366.16 KPA42755.1 - 5.9e-22 77.4 0.2 1.1e-21 76.5 0.2 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KPA42755.1 - 1.5e-07 31.5 0.4 3.9e-07 30.1 0.4 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Zn_clus PF00172.18 KPA42756.1 - 3.4e-07 30.3 11.9 5.5e-07 29.6 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cofilin_ADF PF00241.20 KPA42757.1 - 0.0001 22.1 0.0 0.00025 20.8 0.0 1.7 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein UvdE PF03851.14 KPA42758.1 - 1.1e-107 359.4 0.1 1.6e-107 358.9 0.1 1.3 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF4730 PF15873.5 KPA42759.1 - 0.1 12.9 0.1 0.64 10.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4730) E1-E2_ATPase PF00122.20 KPA42760.1 - 2.4e-36 124.9 14.6 1.5e-29 102.8 0.1 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KPA42760.1 - 8.2e-28 97.3 7.7 8.2e-28 97.3 7.7 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KPA42760.1 - 1.6e-20 74.3 0.0 8.1e-19 68.7 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KPA42760.1 - 1.9e-15 56.7 0.0 4.1e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KPA42760.1 - 9.9e-14 50.8 0.2 9.9e-14 50.8 0.2 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPA42760.1 - 7.5e-05 22.6 0.1 0.00043 20.1 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IPP-2 PF04979.14 KPA42761.1 - 1.2e-24 87.5 7.2 1.2e-24 87.5 7.2 1.6 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Ribosomal_L27 PF01016.19 KPA42763.1 - 1.5e-26 92.2 0.1 3.1e-26 91.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal L27 protein adh_short PF00106.25 KPA42764.1 - 1.6e-31 109.3 0.0 2.1e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA42764.1 - 4.4e-20 72.2 0.0 9.3e-20 71.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA42764.1 - 2.6e-12 47.0 0.0 3.7e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA42764.1 - 0.00021 20.8 0.1 0.00067 19.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPA42764.1 - 0.0013 18.0 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KPA42764.1 - 0.0063 15.9 0.1 1.3 8.3 0.0 2.6 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase ThiF PF00899.21 KPA42764.1 - 1.2 8.4 2.7 5.4 6.3 0.8 2.1 1 1 1 2 2 2 0 ThiF family Leu_zip PF15294.6 KPA42765.1 - 0.00064 19.3 0.2 0.001 18.7 0.2 1.3 1 0 0 1 1 1 1 Leucine zipper HAT_KAT11 PF08214.11 KPA42766.1 - 6.7e-97 324.9 0.0 8.8e-97 324.5 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein 2-Hacid_dh_C PF02826.19 KPA42767.1 - 1.8e-38 131.7 0.0 2.3e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPA42767.1 - 1.1e-10 41.3 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KPA42767.1 - 1.7e-05 25.0 0.0 7e-05 23.0 0.0 1.9 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Alb1 PF09135.11 KPA42768.1 - 2.5e-30 105.5 12.3 2.5e-30 105.5 12.3 1.9 1 1 1 2 2 2 1 Alb1 P120R PF08062.11 KPA42768.1 - 0.51 10.7 4.1 1.8 9.1 4.1 2.0 1 0 0 1 1 1 0 P120R (NUC006) repeat Herpes_UL56 PF04534.12 KPA42768.1 - 1.8 8.0 10.8 0.052 13.0 2.9 2.1 1 1 1 2 2 2 0 Herpesvirus UL56 protein IF3_C PF00707.22 KPA42769.1 - 2.1e-10 40.4 0.5 4e-10 39.5 0.5 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KPA42769.1 - 5.7e-07 29.4 5.8 1.6e-06 28.0 5.2 1.8 1 1 1 2 2 2 1 Mitochondrial translation initiation factor WGR PF05406.15 KPA42769.1 - 0.17 11.9 2.4 0.18 11.9 0.5 2.0 2 0 0 2 2 2 0 WGR domain Peptidase_S24 PF00717.23 KPA42770.1 - 4.1e-07 29.9 0.0 6.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KPA42770.1 - 3.2e-05 23.8 0.0 0.0011 18.7 0.0 2.5 1 1 0 2 2 2 1 Signal peptidase, peptidase S26 Arm PF00514.23 KPA42771.1 - 5.8e-76 248.5 31.9 1.5e-13 50.3 0.1 11.1 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KPA42771.1 - 3.8e-21 75.2 7.3 5.8e-05 23.5 0.1 8.2 6 2 2 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 KPA42771.1 - 2e-17 63.3 7.5 0.00012 22.4 0.1 6.8 4 3 3 7 7 7 4 HEAT repeats HEAT PF02985.22 KPA42771.1 - 3.3e-16 58.0 15.0 0.058 13.7 0.2 8.9 10 0 0 10 10 9 5 HEAT repeat Adaptin_N PF01602.20 KPA42771.1 - 3e-12 45.9 7.7 1.8e-07 30.1 0.3 2.7 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 KPA42771.1 - 9.8e-11 41.6 4.5 2.3e-07 30.6 0.9 2.6 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.12 KPA42771.1 - 1.3e-09 36.8 0.5 2.3e-09 36.0 0.5 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KPA42771.1 - 5.7e-09 35.7 1.4 3.1e-05 23.4 1.2 3.1 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 KPA42771.1 - 4.9e-05 23.4 7.2 0.034 14.2 0.3 4.5 1 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 KPA42771.1 - 5e-05 22.9 4.0 0.9 8.9 0.3 4.8 2 2 3 5 5 5 2 Family of unknown function (DUF5578) V-ATPase_H_C PF11698.8 KPA42771.1 - 0.00011 22.3 1.2 17 5.5 0.1 4.8 2 1 5 7 7 7 0 V-ATPase subunit H IFRD PF05004.13 KPA42771.1 - 0.00052 19.2 2.2 1.7 7.7 0.1 3.9 2 1 1 3 3 3 2 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 KPA42771.1 - 0.0047 17.5 6.5 34 5.5 0.2 6.9 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 KPA42771.1 - 0.016 15.2 1.4 2.3 8.2 0.1 3.5 3 1 2 5 5 5 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 KPA42771.1 - 0.079 13.6 0.1 3.6 8.2 0.0 3.3 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 KPA42771.1 - 0.13 12.3 6.0 5.7 7.0 0.1 4.2 3 2 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain CBS PF00571.28 KPA42772.1 - 7.5e-27 93.5 7.0 1.4e-10 41.4 0.1 4.4 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.27 KPA42773.1 - 3e-09 36.9 0.0 7.1e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PKcGMP_CC PF16808.5 KPA42773.1 - 0.013 15.3 4.1 0.031 14.1 4.1 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fez1 PF06818.15 KPA42773.1 - 0.018 15.5 0.7 0.018 15.5 0.7 2.0 2 0 0 2 2 2 0 Fez1 DUF5565 PF17720.1 KPA42773.1 - 0.17 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5565) Rep_fac-A_3 PF08661.11 KPA42774.1 - 1.7e-24 86.2 0.1 1.8e-24 86.1 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 bZIP_1 PF00170.21 KPA42775.1 - 1.3e-11 44.4 2.6 1.3e-11 44.4 2.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KPA42775.1 - 1.2e-05 25.3 1.4 2.6e-05 24.2 1.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KPA42775.1 - 0.00044 20.7 1.0 0.00044 20.7 1.0 2.1 1 1 1 2 2 2 1 bZIP Maf transcription factor BshC PF10079.9 KPA42775.1 - 0.13 11.0 2.9 0.18 10.5 2.9 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC PBP PF01161.20 KPA42776.1 - 1.9e-06 28.2 0.0 3.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PvlArgDC PF01862.16 KPA42776.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Ribosomal_L4 PF00573.22 KPA42777.1 - 5.6e-47 159.9 0.0 8.8e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PLDc_2 PF13091.6 KPA42778.1 - 3.6e-16 59.3 0.0 1.5e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KPA42778.1 - 5.2e-06 26.4 5.1 0.012 15.8 0.4 3.6 3 1 0 3 3 3 2 Phospholipase D Active site motif NDUFA12 PF05071.16 KPA42779.1 - 4.9e-29 101.0 0.1 5.9e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PNTB PF02233.16 KPA42780.1 - 1.1e-170 568.6 26.1 1.1e-170 568.6 26.1 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KPA42780.1 - 1.1e-72 243.8 0.1 3.1e-72 242.3 0.1 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KPA42780.1 - 3.5e-48 163.3 0.2 1.2e-47 161.6 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KPA42780.1 - 8e-29 99.9 3.3 8e-29 99.9 3.3 5.2 3 1 4 7 7 7 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KPA42780.1 - 0.0062 15.9 0.1 0.32 10.4 0.0 2.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KPA42780.1 - 0.014 15.5 1.0 0.65 10.2 0.2 3.1 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.26 KPA42780.1 - 0.016 15.2 0.1 0.066 13.2 0.1 2.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KPA42780.1 - 0.02 14.2 0.1 0.044 13.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 KPA42780.1 - 0.057 13.2 0.1 0.25 11.1 0.1 2.2 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain NAD_binding_8 PF13450.6 KPA42780.1 - 0.066 13.5 1.4 0.44 10.8 1.4 2.6 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KPA42780.1 - 0.099 11.7 1.0 0.16 11.0 1.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fumerase PF05681.14 KPA42780.1 - 0.1 12.0 0.4 0.29 10.5 0.2 1.8 2 0 0 2 2 2 0 Fumarate hydratase (Fumerase) PRIMA1 PF16101.5 KPA42780.1 - 0.28 11.2 1.5 0.79 9.8 1.5 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ribonucleas_3_3 PF14622.6 KPA42782.1 - 2.9e-25 88.9 0.0 4.6e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Glyoxalase_5 PF14696.6 KPA42782.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Ribonuclease_3 PF00636.26 KPA42782.1 - 0.13 12.9 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease III domain TAF6_C PF07571.13 KPA42784.1 - 2.2e-27 95.2 0.1 4.7e-27 94.1 0.1 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KPA42784.1 - 2.7e-22 78.7 0.0 4.9e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KPA42784.1 - 0.0065 16.8 0.1 0.011 16.1 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KPA42784.1 - 0.0089 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 KPA42784.1 - 0.022 15.0 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KPA42784.1 - 0.1 12.7 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Sdh_cyt PF01127.22 KPA42785.1 - 2.7e-14 53.2 2.1 3.8e-14 52.7 2.1 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fungal_trans PF04082.18 KPA42787.1 - 3.1e-17 62.5 0.2 5.4e-17 61.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA42787.1 - 5.7e-09 36.0 9.2 9.3e-09 35.3 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IPPT PF01715.17 KPA42788.1 - 2.5e-62 210.7 1.5 3.8e-62 210.1 1.5 1.2 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 KPA42788.1 - 2.9e-05 23.6 0.0 0.00011 21.6 0.0 1.9 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 KPA42788.1 - 8.2e-05 22.8 1.2 0.0045 17.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain zf-met PF12874.7 KPA42788.1 - 0.0006 20.1 0.3 0.001 19.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KPA42788.1 - 0.0029 17.9 0.2 0.005 17.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_16 PF13191.6 KPA42788.1 - 0.0087 16.5 0.4 0.024 15.0 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPA42788.1 - 0.022 15.0 0.1 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain zf-C2H2_2 PF12756.7 KPA42788.1 - 0.06 13.7 0.6 0.12 12.7 0.1 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AAA PF00004.29 KPA42788.1 - 0.067 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KPA42788.1 - 0.087 13.2 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 KPA42788.1 - 0.12 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 KPA42788.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KPA42788.1 - 0.17 12.4 3.1 1.2 9.7 0.0 2.9 3 1 0 3 3 3 0 AAA domain CTU2 PF10288.9 KPA42788.1 - 0.26 11.5 3.2 0.12 12.7 0.3 1.8 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF87 PF01935.17 KPA42788.1 - 3.8 7.6 5.4 0.89 9.6 0.1 2.5 3 1 1 4 4 4 0 Helicase HerA, central domain SecY PF00344.20 KPA42789.1 - 2.2e-71 240.6 6.8 2.8e-71 240.3 6.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KPA42789.1 - 3.1e-16 58.9 0.2 9.5e-16 57.4 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p ABC_membrane PF00664.23 KPA42790.1 - 1e-54 186.1 24.3 7.9e-32 111.0 5.7 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KPA42790.1 - 6.9e-53 178.8 0.0 1.9e-31 109.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPA42790.1 - 6.3e-09 35.6 0.2 0.01 15.3 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPA42790.1 - 9.4e-07 29.5 0.1 0.011 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KPA42790.1 - 0.00024 20.8 0.3 0.68 9.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KPA42790.1 - 0.00066 20.1 0.1 0.34 11.3 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 KPA42790.1 - 0.0015 18.4 1.6 14 5.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KPA42790.1 - 0.0021 18.0 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase ResIII PF04851.15 KPA42790.1 - 0.0038 17.3 0.0 2.8 7.9 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 KPA42790.1 - 0.0046 17.0 0.1 0.096 12.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 KPA42790.1 - 0.0056 15.8 0.1 0.41 9.7 0.2 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KPA42790.1 - 0.0083 15.7 0.0 0.59 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KPA42790.1 - 0.014 14.7 0.2 4.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 KPA42790.1 - 0.018 15.3 1.6 5 7.4 0.0 3.4 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KPA42790.1 - 0.02 14.6 0.0 0.63 9.8 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_15 PF13175.6 KPA42790.1 - 0.04 13.6 0.1 16 5.1 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_7 PF12775.7 KPA42790.1 - 0.043 13.3 0.1 11 5.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KPA42790.1 - 0.059 13.1 0.8 10 5.8 0.1 2.9 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KPA42790.1 - 0.075 13.1 0.0 0.075 13.1 0.0 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain DEAD PF00270.29 KPA42790.1 - 0.15 11.8 0.0 21 4.8 0.0 3.4 4 0 0 4 4 3 0 DEAD/DEAH box helicase AAA PF00004.29 KPA42790.1 - 0.15 12.5 0.3 68 3.9 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KPA42790.1 - 0.15 11.7 0.1 0.6 9.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KPA42790.1 - 0.21 11.5 1.2 28 4.6 0.1 3.3 3 0 0 3 3 3 0 NTPase TrwB_AAD_bind PF10412.9 KPA42790.1 - 1 8.2 3.3 15 4.3 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Gram_pos_anchor PF00746.21 KPA42790.1 - 2 8.4 4.5 0.71 9.9 0.3 2.7 2 0 0 2 2 1 0 LPXTG cell wall anchor motif Adaptin_binding PF10199.9 KPA42792.1 - 3.9e-12 46.8 8.8 7.8e-12 45.9 8.8 1.5 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Homeodomain PF00046.29 KPA42793.1 - 5.6e-20 70.9 4.3 1.2e-19 69.9 4.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KPA42793.1 - 0.0014 18.5 0.6 0.0048 16.8 0.6 1.9 1 0 0 1 1 1 1 Homeobox KN domain SWIRM-assoc_2 PF16496.5 KPA42793.1 - 0.14 11.0 4.0 0.21 10.4 4.0 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal PhoLip_ATPase_C PF16212.5 KPA42794.1 - 1.3e-72 244.6 23.6 2.6e-72 243.6 23.6 1.5 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KPA42794.1 - 1.2e-22 79.4 0.4 1.4e-20 72.7 0.1 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KPA42794.1 - 3e-12 46.4 0.0 3.5e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KPA42794.1 - 1.9e-11 43.8 1.4 3.9e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KPA42794.1 - 2.4e-11 44.3 0.0 0.00017 21.9 0.0 3.6 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KPA42794.1 - 0.0013 18.5 0.0 0.0045 16.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPA42794.1 - 0.12 12.7 0.8 8.2 6.8 0.0 3.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Synaptobrevin PF00957.21 KPA42795.1 - 5.9e-32 109.3 0.4 7.9e-32 108.9 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KPA42795.1 - 2e-29 101.4 0.0 3.5e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SUV3_C PF12513.8 KPA42796.1 - 9.5e-17 60.7 0.7 9.5e-17 60.7 0.7 2.1 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KPA42796.1 - 1.2e-09 38.4 0.0 2.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KPA42796.1 - 3.5e-09 36.4 0.3 7.9e-09 35.2 0.3 1.7 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 DSPc PF00782.20 KPA42797.1 - 1.1e-08 34.9 0.0 2.4e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KPA42797.1 - 0.019 15.3 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain AT_hook PF02178.19 KPA42798.1 - 0.032 14.1 4.0 0.032 14.1 4.0 2.5 2 0 0 2 2 2 0 AT hook motif SOG2 PF10428.9 KPA42798.1 - 3.1 6.9 8.2 4.1 6.5 8.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ribonuclease_3 PF00636.26 KPA42800.1 - 2e-41 140.9 0.3 4.3e-19 69.1 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KPA42800.1 - 1.1e-26 93.4 0.0 7.7e-11 42.3 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KPA42800.1 - 1.1e-20 73.6 0.5 6.8e-20 71.0 0.5 2.5 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KPA42800.1 - 5.7e-17 62.1 0.1 1.8e-16 60.5 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA42800.1 - 6.3e-14 52.3 0.1 1.6e-13 51.0 0.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPA42800.1 - 1.1e-11 44.9 0.0 2.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF87 PF01935.17 KPA42800.1 - 0.011 15.8 0.6 1.4 9.0 0.1 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain Peptidase_C12 PF01088.21 KPA42802.1 - 8.7e-55 185.7 0.0 1.1e-54 185.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Arf PF00025.21 KPA42803.1 - 5.5e-25 87.8 0.0 1.2e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KPA42803.1 - 4.1e-07 30.2 0.0 9.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KPA42803.1 - 1.8e-05 24.3 0.0 3.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KPA42803.1 - 3.3e-05 23.5 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KPA42803.1 - 5.7e-05 22.6 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KPA42803.1 - 0.0003 20.1 0.1 0.083 12.0 0.2 3.1 1 1 2 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KPA42803.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase EBP PF05241.12 KPA42805.1 - 2.4e-57 193.3 10.6 3e-57 192.9 10.6 1.1 1 0 0 1 1 1 1 Emopamil binding protein Fungal_trans_2 PF11951.8 KPA42806.1 - 3.2e-09 36.1 1.5 4.3e-09 35.7 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA42806.1 - 6.7e-08 32.5 7.6 1.2e-07 31.7 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vma12 PF11712.8 KPA42807.1 - 1e-45 155.2 0.0 2.4e-45 154.0 0.0 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-C2H2_3 PF13878.6 KPA42807.1 - 3e-08 33.3 0.0 6.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DUF4212 PF13937.6 KPA42807.1 - 0.044 14.2 0.4 0.074 13.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) polyprenyl_synt PF00348.17 KPA42808.1 - 1.2e-73 247.3 0.0 2.1e-73 246.6 0.0 1.3 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KPA42808.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Amidohydro_1 PF01979.20 KPA42809.1 - 1.9e-26 93.2 0.0 8.4e-26 91.1 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPA42809.1 - 4.1e-13 49.6 0.1 7.2e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family ABC_tran PF00005.27 KPA42810.1 - 3.1e-48 163.8 0.0 4.5e-24 85.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KPA42810.1 - 2e-47 161.3 37.7 3.1e-27 95.4 12.2 2.9 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.6 KPA42810.1 - 2e-13 50.8 7.1 0.013 15.3 0.0 4.5 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPA42810.1 - 3.3e-09 36.5 0.4 0.0021 17.5 0.1 4.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KPA42810.1 - 4.1e-08 33.8 0.3 0.0057 17.1 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KPA42810.1 - 6e-08 33.0 0.0 0.038 14.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KPA42810.1 - 7.4e-08 33.1 2.5 0.00078 20.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KPA42810.1 - 2e-07 31.1 0.9 0.022 14.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KPA42810.1 - 1.2e-06 28.2 5.5 0.011 15.5 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain NACHT PF05729.12 KPA42810.1 - 1.2e-06 28.5 0.0 0.055 13.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.6 KPA42810.1 - 4.3e-06 27.1 0.5 0.0074 16.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPA42810.1 - 7.2e-06 25.9 0.4 0.044 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KPA42810.1 - 1.1e-05 25.7 0.7 0.085 13.1 0.3 2.7 3 0 0 3 3 2 2 AAA domain cobW PF02492.19 KPA42810.1 - 7.1e-05 22.5 0.6 0.28 10.7 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KPA42810.1 - 7.4e-05 22.4 0.4 0.36 10.4 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KPA42810.1 - 0.00012 21.9 1.6 2.8 7.6 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain T2SSE PF00437.20 KPA42810.1 - 0.00019 20.6 0.7 0.46 9.5 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein ATPase_2 PF01637.18 KPA42810.1 - 0.00057 19.9 0.0 0.46 10.3 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KPA42810.1 - 0.00067 20.0 0.1 1.8 9.0 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_24 PF13479.6 KPA42810.1 - 0.0011 18.7 0.7 1 9.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KPA42810.1 - 0.0018 18.3 2.2 0.79 9.8 0.2 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.6 KPA42810.1 - 0.0025 18.0 0.4 3.1 8.1 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KPA42810.1 - 0.0046 17.5 0.3 4 8.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 KPA42810.1 - 0.0066 16.6 1.8 1.1 9.5 0.6 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KPA42810.1 - 0.0072 16.8 0.1 10 6.6 0.0 3.1 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KPA42810.1 - 0.012 15.5 1.2 2.3 8.1 0.1 3.7 4 0 0 4 4 4 0 NTPase FtsK_SpoIIIE PF01580.18 KPA42810.1 - 0.012 15.0 1.5 2.1 7.7 0.1 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 KPA42810.1 - 0.015 15.5 0.2 5.4 7.3 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KPA42810.1 - 0.018 15.0 0.8 9 6.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MobB PF03205.14 KPA42810.1 - 0.021 14.7 0.6 3.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.16 KPA42810.1 - 0.025 14.0 0.3 3.2 7.1 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 KPA42810.1 - 0.036 13.3 0.1 4.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_ATPase PF09818.9 KPA42810.1 - 0.041 12.7 0.4 1 8.1 0.1 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Septin PF00735.18 KPA42810.1 - 0.042 13.1 0.2 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Septin Pox_A32 PF04665.12 KPA42810.1 - 0.058 12.9 1.3 1.6 8.2 0.2 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein PduV-EutP PF10662.9 KPA42810.1 - 0.063 13.0 0.3 10 5.9 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KPA42810.1 - 0.084 12.3 0.4 11 5.3 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PRK PF00485.18 KPA42810.1 - 0.097 12.4 0.4 6.7 6.4 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 KPA42810.1 - 0.1 12.2 0.6 15 5.1 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KPA42810.1 - 0.12 12.1 1.0 6.6 6.4 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein PDR_CDR PF06422.12 KPA42810.1 - 0.16 11.9 0.1 0.4 10.6 0.1 1.6 1 0 0 1 1 1 0 CDR ABC transporter AAA_17 PF13207.6 KPA42810.1 - 0.16 12.4 0.2 3.3 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KPA42810.1 - 0.18 11.8 0.3 14 5.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KPA42810.1 - 0.21 11.3 5.7 1.6 8.4 0.1 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 KPA42810.1 - 0.28 10.4 0.6 17 4.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin DUF3987 PF13148.6 KPA42810.1 - 0.72 8.8 6.0 23 3.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Mannosyl_trans3 PF11051.8 KPA42811.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KPA42811.1 - 0.0062 16.1 0.6 0.02 14.5 0.6 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 MFS_1 PF07690.16 KPA42813.1 - 1.2e-32 113.2 23.9 1.7e-32 112.7 23.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5455 PF17537.2 KPA42813.1 - 0.0061 17.0 0.2 0.024 15.0 0.2 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5455) PgaD PF13994.6 KPA42813.1 - 1.8 8.6 5.6 1.8 8.6 0.0 3.1 3 0 0 3 3 3 0 PgaD-like protein Ribonuc_L-PSP PF01042.21 KPA42814.1 - 7.5e-35 119.6 0.0 8.4e-35 119.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF3659 PF12396.8 KPA42814.1 - 0.14 12.1 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) TetM_leader PF08076.11 KPA42815.1 - 0.082 12.7 0.7 0.19 11.5 0.7 1.6 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide Acyl-CoA_dh_1 PF00441.24 KPA42816.1 - 7.6e-25 87.9 3.0 4.5e-24 85.4 2.5 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPA42816.1 - 1.7e-19 69.8 0.0 8.1e-19 67.6 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPA42816.1 - 2.7e-09 37.4 4.0 2.7e-09 37.4 4.0 3.3 4 1 0 4 4 4 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPA42816.1 - 3.3e-09 37.4 0.1 1e-08 35.8 0.1 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Aconitase PF00330.20 KPA42817.1 - 4.1e-111 372.2 0.2 3.9e-110 369.0 0.2 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KPA42817.1 - 2.5e-25 89.3 0.0 5e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Birna_VP3 PF01767.16 KPA42817.1 - 0.085 12.9 0.2 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Birnavirus VP3 protein MaoC_dehydrat_N PF13452.6 KPA42819.1 - 4.2e-05 23.7 0.0 7.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase 2-oxoacid_dh PF00198.23 KPA42820.1 - 1e-78 264.0 0.5 1.3e-78 263.6 0.5 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KPA42820.1 - 8.5e-13 47.9 1.2 8.5e-13 47.9 1.2 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme DUF5089 PF17002.5 KPA42820.1 - 0.013 15.4 4.9 0.033 14.0 4.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) Biotin_lipoyl_2 PF13533.6 KPA42820.1 - 0.047 13.5 0.1 1 9.3 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.6 KPA42820.1 - 0.072 13.8 0.4 14 6.4 0.1 2.4 1 1 1 2 2 2 0 HlyD family secretion protein DUF3614 PF12267.8 KPA42820.1 - 0.073 13.6 4.7 0.43 11.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) RNA_pol_Rpc4 PF05132.14 KPA42820.1 - 0.24 11.8 6.6 0.44 11.0 6.6 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 SRP-alpha_N PF04086.13 KPA42820.1 - 0.33 10.8 10.3 0.47 10.3 10.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 KPA42820.1 - 0.58 8.9 4.8 0.8 8.4 4.8 1.1 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 KPA42820.1 - 0.65 8.7 5.2 0.76 8.5 0.0 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Hamartin PF04388.12 KPA42820.1 - 6.8 5.2 7.7 9.2 4.8 7.7 1.1 1 0 0 1 1 1 0 Hamartin protein DUF4551 PF15087.6 KPA42820.1 - 7.4 5.3 6.1 9.7 4.9 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3275 PF11679.8 KPA42820.1 - 8 6.4 6.8 16 5.4 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Ndc1_Nup PF09531.10 KPA42820.1 - 8.1 5.0 5.5 10 4.7 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Fig1 PF12351.8 KPA42821.1 - 0.15 11.9 4.7 0.29 11.0 4.7 1.4 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 ELYS PF13934.6 KPA42822.1 - 4.9e-68 229.4 0.8 5.8e-68 229.2 0.8 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.19 KPA42823.1 - 4.7e-64 215.8 53.5 5.7e-63 212.3 53.5 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KPA42823.1 - 4.7e-24 84.9 0.0 1.7e-23 83.2 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KPA42823.1 - 2.1e-12 47.5 0.8 5.6e-05 23.1 0.4 3.2 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system IFT57 PF10498.9 KPA42823.1 - 3.3e-05 23.0 15.9 3.3e-05 23.0 15.9 5.9 2 2 4 6 6 5 1 Intra-flagellar transport protein 57 Tropomyosin_1 PF12718.7 KPA42823.1 - 0.00019 21.6 8.2 0.00019 21.6 8.2 8.3 3 3 5 8 8 7 3 Tropomyosin like AAA_29 PF13555.6 KPA42823.1 - 0.00033 20.3 0.0 0.00068 19.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1664 PF07889.12 KPA42823.1 - 0.00079 19.5 2.8 0.00079 19.5 2.8 8.6 4 2 5 9 9 9 4 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KPA42823.1 - 0.0076 16.4 16.6 0.0076 16.4 16.6 7.6 2 2 5 7 7 5 2 Uncharacterised protein family (UPF0242) N-terminus DUF4201 PF13870.6 KPA42823.1 - 0.019 14.7 95.4 0.025 14.3 14.1 7.5 3 2 3 7 7 7 0 Domain of unknown function (DUF4201) AT_hook PF02178.19 KPA42823.1 - 0.2 11.6 6.2 1.1 9.3 6.2 2.4 1 0 0 1 1 1 0 AT hook motif ABC_tran PF00005.27 KPA42823.1 - 0.53 10.8 0.0 0.53 10.8 0.0 6.5 4 3 0 4 4 2 0 ABC transporter ATG16 PF08614.11 KPA42823.1 - 2.9 8.1 118.2 0.82 9.9 19.0 8.8 3 2 3 6 6 6 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KPA42823.1 - 5.6 5.8 131.2 0.4 9.5 6.4 7.8 3 2 4 8 8 8 0 Spc7 kinetochore protein MscS_porin PF12795.7 KPA42823.1 - 6.4 6.3 96.0 1.5 8.3 25.8 6.4 3 2 4 7 7 7 0 Mechanosensitive ion channel porin domain Ribosomal_S26e PF01283.19 KPA42825.1 - 2.6e-52 175.8 9.1 3e-52 175.6 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KPA42825.1 - 0.012 15.5 0.4 0.052 13.5 0.0 2.0 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 KPA42825.1 - 0.24 11.2 2.5 0.23 11.3 1.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) ubiquitin PF00240.23 KPA42826.1 - 4.7e-34 116.0 0.9 7.8e-34 115.3 0.6 1.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 KPA42826.1 - 1.7e-26 92.1 1.7 1.7e-26 92.1 1.7 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KPA42826.1 - 2.4e-16 59.3 0.7 4.8e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KPA42826.1 - 2.4e-05 24.7 0.5 0.00013 22.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KPA42826.1 - 0.0012 18.9 0.7 0.0026 17.8 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KPA42826.1 - 0.0047 17.3 0.9 0.0078 16.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KPA42826.1 - 0.0054 16.6 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KPA42826.1 - 0.011 16.3 0.6 0.015 15.8 0.6 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KPA42826.1 - 0.019 15.0 1.0 5.8 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Glyco_hydro_18 PF00704.28 KPA42827.1 - 2.3e-85 287.1 0.7 2.7e-85 286.9 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CagY_I PF14585.6 KPA42827.1 - 0.095 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 CagY type 1 repeat Glyco_hydro_20 PF00728.22 KPA42828.1 - 9.4e-31 107.5 1.0 5.8e-28 98.3 1.0 2.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KPA42828.1 - 3.3e-11 44.1 0.1 8.9e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Mannosyl_trans3 PF11051.8 KPA42829.1 - 0.0043 16.4 0.3 0.0043 16.4 0.3 1.6 2 0 0 2 2 2 1 Mannosyltransferase putative Asp PF00026.23 KPA42831.1 - 1.4e-11 44.4 0.0 2.6e-11 43.5 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 KPA42831.1 - 0.054 12.9 7.0 0.11 11.9 7.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TBK1_CCD1 PF18394.1 KPA42832.1 - 0.005 16.4 0.1 0.0079 15.8 0.1 1.2 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 MtaB PF12176.8 KPA42834.1 - 0.087 11.6 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit An_peroxidase PF03098.15 KPA42835.1 - 6.9e-41 140.4 0.0 6.9e-29 100.8 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KPA42835.1 - 1.3e-12 47.2 0.0 6e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 JAB PF01398.21 KPA42836.1 - 2.5e-12 46.8 0.0 4.5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KPA42836.1 - 1.6e-08 34.7 0.1 2.9e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KPA42836.1 - 4.5e-05 23.2 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Dsl1_N PF11988.8 KPA42837.1 - 0.015 14.3 0.3 0.026 13.5 0.2 1.4 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal Prefoldin_2 PF01920.20 KPA42838.1 - 8.9e-20 70.6 10.9 1.1e-19 70.4 10.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit WEMBL PF05701.11 KPA42838.1 - 0.0021 16.8 4.3 0.0028 16.4 4.3 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Spc7 PF08317.11 KPA42838.1 - 0.0023 16.9 8.7 0.0029 16.5 8.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein HSBP1 PF06825.12 KPA42838.1 - 0.01 15.7 1.5 0.053 13.4 0.0 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Spc24 PF08286.11 KPA42838.1 - 0.01 16.0 6.7 0.76 10.1 0.5 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 MAD PF05557.13 KPA42838.1 - 0.018 13.5 8.4 0.021 13.2 8.4 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Prefoldin_3 PF13758.6 KPA42838.1 - 0.026 14.6 1.9 0.049 13.7 1.9 1.5 1 1 0 1 1 1 0 Prefoldin subunit DUF5082 PF16888.5 KPA42838.1 - 0.033 14.5 8.5 0.55 10.5 8.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) PHM7_cyt PF14703.6 KPA42838.1 - 0.053 13.8 4.0 0.096 12.9 4.0 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MIP-T3_C PF17749.1 KPA42838.1 - 0.064 13.2 6.2 0.16 11.9 1.3 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region BRE1 PF08647.11 KPA42838.1 - 0.1 12.7 11.4 0.25 11.5 1.5 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4164 PF13747.6 KPA42838.1 - 0.12 12.7 4.1 5.2 7.4 0.9 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF641 PF04859.12 KPA42838.1 - 0.19 12.1 5.5 0.57 10.5 0.9 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4201 PF13870.6 KPA42838.1 - 0.2 11.4 6.9 0.89 9.3 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Laminin_I PF06008.14 KPA42838.1 - 0.2 11.3 9.3 1.3 8.7 9.3 2.0 1 1 0 1 1 1 0 Laminin Domain I Occludin_ELL PF07303.13 KPA42838.1 - 0.24 12.2 3.7 0.73 10.6 0.6 2.2 2 0 0 2 2 2 0 Occludin homology domain TMF_TATA_bd PF12325.8 KPA42838.1 - 0.27 11.4 7.6 2.5 8.4 1.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 KPA42838.1 - 0.31 11.1 10.5 0.084 13.0 1.7 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding LPP PF04728.13 KPA42838.1 - 0.32 11.4 4.8 9.4 6.7 0.2 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ABC_tran_CTD PF16326.5 KPA42838.1 - 0.41 10.9 9.8 1.4 9.2 0.3 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain UPF0242 PF06785.11 KPA42838.1 - 0.5 10.4 13.1 2.3 8.3 13.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KPA42838.1 - 0.62 9.4 10.7 0.5 9.7 2.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Rx_N PF18052.1 KPA42838.1 - 0.63 10.4 5.3 0.93 9.8 1.1 2.2 2 0 0 2 2 2 0 Rx N-terminal domain DHR10 PF18595.1 KPA42838.1 - 0.67 10.0 11.8 0.53 10.4 3.2 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain OmpH PF03938.14 KPA42838.1 - 0.7 10.2 20.8 3 8.2 4.8 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) LPP20 PF02169.16 KPA42838.1 - 0.7 10.3 4.4 1.4 9.3 4.4 1.8 1 1 0 1 1 1 0 LPP20 lipoprotein FlaC_arch PF05377.11 KPA42838.1 - 0.83 10.1 4.0 12 6.4 0.0 2.9 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) zf-C4H2 PF10146.9 KPA42838.1 - 0.87 9.9 5.8 0.75 10.1 0.9 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein Prefoldin PF02996.17 KPA42838.1 - 0.88 9.5 9.8 0.22 11.5 1.7 2.3 1 1 1 2 2 2 0 Prefoldin subunit NPV_P10 PF05531.12 KPA42838.1 - 1 9.9 3.4 8.9 6.9 0.9 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein COX16 PF14138.6 KPA42838.1 - 1.2 9.7 5.2 0.37 11.3 1.1 2.0 1 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Golgin_A5 PF09787.9 KPA42838.1 - 1.4 8.3 12.0 0.19 11.2 1.0 2.0 1 1 0 2 2 2 0 Golgin subfamily A member 5 TolA_bind_tri PF16331.5 KPA42838.1 - 1.7 8.8 14.7 5 7.3 7.4 2.8 2 1 0 2 2 2 0 TolA binding protein trimerisation Cep57_MT_bd PF06657.13 KPA42838.1 - 1.8 9.1 7.0 17 6.0 0.3 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SlyX PF04102.12 KPA42838.1 - 3.1 8.5 10.9 1.5 9.5 0.4 2.8 2 1 1 3 3 3 0 SlyX DivIC PF04977.15 KPA42838.1 - 5.4 6.9 16.8 5 7.0 1.4 3.7 2 2 2 4 4 4 0 Septum formation initiator YabA PF06156.13 KPA42838.1 - 5.4 7.7 7.5 10 6.8 2.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA AAA PF00004.29 KPA42839.1 - 1.6e-41 141.9 0.0 4.2e-41 140.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KPA42839.1 - 1.6e-26 92.1 0.1 6.9e-26 90.0 0.2 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KPA42839.1 - 4.6e-17 61.8 3.9 1.3e-16 60.4 3.9 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KPA42839.1 - 1.3e-07 31.3 0.0 5.8e-07 29.2 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 KPA42839.1 - 4.5e-07 29.7 0.0 8.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KPA42839.1 - 1.6e-05 24.3 0.0 3.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KPA42839.1 - 1.9e-05 25.1 0.1 0.0023 18.4 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KPA42839.1 - 3.4e-05 23.7 0.0 8.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KPA42839.1 - 3.9e-05 23.9 0.2 0.019 15.2 0.0 3.2 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 KPA42839.1 - 5.5e-05 23.5 0.0 0.011 16.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 KPA42839.1 - 8.1e-05 22.7 0.0 0.00022 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KPA42839.1 - 0.00012 22.1 0.0 0.0006 19.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KPA42839.1 - 0.00021 20.5 0.1 0.00092 18.4 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KPA42839.1 - 0.00055 19.7 1.9 0.0067 16.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain PrkA PF06798.12 KPA42839.1 - 0.00097 18.8 0.1 0.0058 16.3 0.0 2.0 2 0 0 2 2 2 1 PrkA serine protein kinase C-terminal domain AAA_18 PF13238.6 KPA42839.1 - 0.0012 19.4 0.1 0.004 17.7 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KPA42839.1 - 0.0042 17.3 0.0 0.0096 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KPA42839.1 - 0.008 16.3 0.0 0.027 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KPA42839.1 - 0.023 14.3 0.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KPA42839.1 - 0.025 14.1 0.1 0.13 11.8 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 KPA42839.1 - 0.026 15.0 0.0 0.07 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KPA42839.1 - 0.029 13.8 0.0 0.082 12.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 KPA42839.1 - 0.031 14.1 0.2 3.2 7.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NRDE-2 PF08424.10 KPA42839.1 - 0.055 12.6 0.5 0.087 11.9 0.5 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference PhoH PF02562.16 KPA42839.1 - 0.068 12.6 0.4 0.16 11.4 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 KPA42839.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TPR_12 PF13424.6 KPA42839.1 - 0.11 12.8 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Torsin PF06309.11 KPA42839.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Torsin NACHT PF05729.12 KPA42839.1 - 0.13 12.2 0.0 0.66 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Cytidylate_kin PF02224.18 KPA42839.1 - 0.16 11.7 0.3 0.62 9.8 0.1 2.1 2 0 0 2 2 2 0 Cytidylate kinase RrnaAD PF00398.20 KPA42840.1 - 2.2e-07 30.2 0.0 4.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Glyco_transf_90 PF05686.12 KPA42841.1 - 1.7e-15 56.9 2.7 1.7e-11 43.7 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferase family 90 CblD PF07434.11 KPA42841.1 - 0.17 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator Arginase PF00491.21 KPA42842.1 - 1.8e-74 250.7 0.3 2.2e-74 250.5 0.3 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.23 KPA42843.1 - 2.3e-07 30.9 11.4 2.7e-06 27.5 11.1 2.1 1 1 1 2 2 2 2 Membrane-associating domain Collagen PF01391.18 KPA42843.1 - 0.038 13.7 0.4 0.061 13.1 0.4 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Cnn_1N PF07989.11 KPA42845.1 - 4.8e-22 77.9 6.9 4.8e-22 77.9 6.9 13.1 10 1 2 13 13 13 4 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KPA42845.1 - 6.4e-10 39.2 9.6 6.4e-10 39.2 9.6 13.9 15 2 1 16 16 16 1 Micro-tubular organiser Mto1 C-term Mto2-binding region NPV_P10 PF05531.12 KPA42845.1 - 0.23 11.9 0.0 0.23 11.9 0.0 6.7 7 1 0 7 7 7 0 Nucleopolyhedrovirus P10 protein DUF1479 PF07350.12 KPA42846.1 - 9.9e-163 541.7 0.0 1.2e-162 541.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KPA42846.1 - 0.015 15.6 0.1 8.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) CorA PF01544.18 KPA42848.1 - 6e-05 22.5 0.3 0.00012 21.5 0.1 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3177 PF11375.8 KPA42848.1 - 0.0053 16.6 0.1 0.0081 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3177) Peptidase_S15 PF02129.18 KPA42848.1 - 0.031 13.9 0.5 0.046 13.3 0.5 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1993 PF09351.10 KPA42849.1 - 1.7e-50 171.3 0.0 1.9e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) HSM3_N PF18795.1 KPA42849.1 - 0.047 13.1 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain Mrx7 PF10906.8 KPA42850.1 - 5e-10 39.5 0.0 6.3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 MIOREX complex component 7 Fungal_trans PF04082.18 KPA42852.1 - 2.1e-08 33.6 0.0 3.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MCC-bdg_PDZ PF10506.9 KPA42853.1 - 0.39 10.8 6.7 5.1 7.2 0.2 3.9 4 1 1 5 5 5 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3500 PF12006.8 KPA42853.1 - 0.41 10.1 2.5 13 5.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3500) GCN5L1 PF06320.13 KPA42853.1 - 0.42 10.8 27.5 0.12 12.5 2.7 5.0 5 1 1 6 6 6 0 GCN5-like protein 1 (GCN5L1) Filament PF00038.21 KPA42853.1 - 0.81 9.2 43.5 0.15 11.6 5.8 5.0 3 2 2 5 5 5 0 Intermediate filament protein ADK PF00406.22 KPA42853.1 - 1.1 9.3 5.6 0.66 10.1 3.3 1.7 2 0 0 2 2 2 0 Adenylate kinase Bacillus_HBL PF05791.11 KPA42853.1 - 1.3 8.8 17.7 1.7 8.4 1.3 4.8 3 1 2 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) Prominin PF05478.11 KPA42853.1 - 1.5 6.6 14.0 2.9 5.7 6.5 3.1 2 1 0 3 3 3 0 Prominin HIP1_clath_bdg PF16515.5 KPA42853.1 - 2.4 8.8 44.1 0.04 14.5 4.2 5.8 5 1 1 6 6 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0242 PF06785.11 KPA42853.1 - 3.7 7.6 36.7 3 7.9 11.3 4.5 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 KPA42853.1 - 4.2 7.3 30.4 0.69 9.8 0.6 5.9 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 KPA42853.1 - 4.3 6.1 40.4 0.68 8.8 3.8 4.4 3 1 0 4 4 4 0 Spc7 kinetochore protein DUF4407 PF14362.6 KPA42853.1 - 5 6.4 31.0 17 4.7 2.3 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Mpv17_PMP22 PF04117.12 KPA42854.1 - 2.3e-15 56.6 0.6 5.1e-15 55.4 0.6 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Fungal_trans PF04082.18 KPA42855.1 - 1.1e-20 73.8 0.0 1.6e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA42855.1 - 1.5e-05 25.0 7.9 3e-05 24.0 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.14 KPA42856.1 - 3.7e-105 351.4 2.9 5.8e-105 350.7 2.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KPA42856.1 - 8.4e-45 153.0 0.0 1.6e-44 152.1 0.0 1.5 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain ECH_1 PF00378.20 KPA42856.1 - 2.2e-22 79.6 0.0 7.2e-20 71.4 0.0 2.4 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA42856.1 - 2e-10 40.7 0.1 1.4e-06 28.1 0.0 3.1 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase DPPIV_N PF00930.21 KPA42857.1 - 9.2e-112 373.3 1.8 1.3e-111 372.8 1.3 1.5 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KPA42857.1 - 3.3e-38 131.3 2.3 5.9e-38 130.5 2.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.14 KPA42857.1 - 0.066 12.5 0.1 0.14 11.4 0.1 1.5 1 0 0 1 1 1 0 Secretory lipase PD40 PF07676.12 KPA42857.1 - 0.14 12.2 1.3 1.3 9.0 0.2 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Peptidase_S15 PF02129.18 KPA42857.1 - 0.62 9.6 5.3 1.3 8.6 2.1 2.7 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Phage_holin_3_2 PF04550.12 KPA42858.1 - 0.013 16.0 1.6 0.036 14.6 0.2 2.3 2 0 0 2 2 2 0 Phage holin family 2 p450 PF00067.22 KPA42859.1 - 2.9e-44 151.6 0.0 3.8e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KPA42860.1 - 1.9e-22 79.7 16.3 2.3e-22 79.4 16.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA42860.1 - 1.8e-13 50.2 7.0 2.2e-13 49.9 7.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KPA42860.1 - 0.001 18.5 0.5 0.0014 18.0 0.5 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Bacteriocin_IIc PF10439.9 KPA42861.1 - 1.7 8.8 7.4 0.98 9.6 0.1 3.1 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide TPR_14 PF13428.6 KPA42864.1 - 9.1e-26 88.3 23.7 9.2e-06 26.1 0.1 10.3 7 4 4 11 11 10 6 Tetratricopeptide repeat HAT PF02184.16 KPA42864.1 - 2.1e-19 69.2 74.7 1.6e-11 44.0 2.2 13.1 16 0 0 16 16 15 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 KPA42864.1 - 1.9e-17 63.5 0.6 5e-06 26.9 0.0 6.6 5 1 2 7 7 7 3 Tetratricopeptide repeat Suf PF05843.14 KPA42864.1 - 3.2e-17 63.5 20.1 0.00049 20.2 5.2 6.8 3 1 2 5 5 5 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 KPA42864.1 - 1e-09 38.1 9.8 0.00019 21.6 0.1 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KPA42864.1 - 9.1e-09 35.8 13.9 0.052 14.2 0.1 7.7 7 1 2 9 9 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 KPA42864.1 - 2.3e-07 30.3 18.4 0.0089 15.3 2.2 5.7 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 KPA42864.1 - 4.9e-06 26.8 26.0 0.62 10.8 0.0 8.7 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPA42864.1 - 1.4e-05 24.8 23.9 0.034 14.2 0.2 8.1 8 1 1 9 9 9 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KPA42864.1 - 0.00026 20.3 25.6 0.2 10.7 3.5 5.6 3 3 1 4 4 4 3 NRDE-2, necessary for RNA interference U3_assoc_6 PF08640.11 KPA42864.1 - 0.0034 17.4 25.0 0.084 12.9 0.9 7.0 6 2 1 7 7 6 1 U3 small nucleolar RNA-associated protein 6 ANAPC3 PF12895.7 KPA42864.1 - 0.0087 16.3 3.8 0.9 9.8 0.0 4.5 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KPA42864.1 - 0.022 14.9 11.7 15 6.1 0.1 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat ECSIT PF06239.11 KPA42864.1 - 0.083 12.0 3.9 0.11 11.6 0.1 2.7 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway Fis1_TPR_C PF14853.6 KPA42864.1 - 0.37 10.9 15.5 16 5.6 0.6 6.2 7 1 1 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 KPA42864.1 - 1 9.3 11.2 3.7 7.5 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KPA42864.1 - 1.4 8.9 32.3 1.4 8.9 0.1 7.1 4 3 4 8 8 8 0 Mad3/BUB1 homology region 1 Strep_SA_rep PF06696.11 KPA42864.1 - 2.1 8.4 6.3 3.6 7.7 1.6 2.6 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Nop PF01798.18 KPA42865.1 - 8.2e-72 241.4 0.0 1.2e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KPA42865.1 - 7.3e-46 156.0 1.7 3.2e-45 153.9 1.7 2.2 1 0 0 1 1 1 1 Prp31 C terminal domain RRN3 PF05327.11 KPA42865.1 - 3.2 6.2 9.8 4.8 5.6 9.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-C2H2 PF00096.26 KPA42866.1 - 2.9e-05 24.3 9.8 0.0024 18.2 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA42866.1 - 0.0056 17.4 8.1 0.11 13.3 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPA42866.1 - 0.0096 16.3 0.7 0.0096 16.3 0.7 2.8 3 0 0 3 3 3 1 Zinc-finger double domain Integrin_B_tail PF07965.12 KPA42866.1 - 0.034 14.6 0.6 0.074 13.6 0.2 1.7 1 1 1 2 2 2 0 Integrin beta tail domain zf-met PF12874.7 KPA42866.1 - 0.089 13.2 6.6 0.37 11.3 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Acetate_kinase PF00871.17 KPA42867.1 - 4.1e-88 295.7 0.0 5e-88 295.4 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Sugar_tr PF00083.24 KPA42869.1 - 1.2e-21 77.2 19.9 1.1e-17 64.0 7.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPA42869.1 - 1.7e-17 63.4 21.1 2.4e-17 62.9 9.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KPA42870.1 - 8.9e-20 70.8 0.0 1.4e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA42870.1 - 5.3e-09 36.0 11.6 8.5e-09 35.4 9.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KPA42871.1 - 5.9e-20 71.2 7.2 0.00028 21.6 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA42871.1 - 8.3e-13 48.5 0.0 0.036 14.4 0.0 5.8 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA42871.1 - 0.012 14.6 0.0 2.4 7.0 0.0 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 KPA42871.1 - 0.019 14.1 0.0 3.7 6.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) Nup160 PF11715.8 KPA42871.1 - 0.031 12.9 0.2 0.17 10.5 0.1 2.1 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Ras PF00071.22 KPA42871.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Ras family Cyclin_N PF00134.23 KPA42872.1 - 4.2e-44 149.4 0.0 1.3e-43 147.8 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KPA42872.1 - 9.2e-34 116.1 0.0 1.5e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.18 KPA42873.1 - 1.6e-50 170.5 3.9 5.4e-50 168.8 4.1 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KPA42873.1 - 9.1e-24 83.2 1.6 1.7e-23 82.3 0.6 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain PAP2 PF01569.21 KPA42874.1 - 2.4e-21 75.9 1.6 7.1e-13 48.5 0.1 2.6 2 0 0 2 2 2 2 PAP2 superfamily CK_II_beta PF01214.18 KPA42875.1 - 4.2e-77 258.1 0.1 5.1e-77 257.8 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PBP1_TM PF14812.6 KPA42875.1 - 3.1 8.2 9.7 0.44 10.9 5.3 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RIC1 PF07064.13 KPA42876.1 - 9.6e-93 310.2 0.1 1.3e-92 309.7 0.1 1.2 1 0 0 1 1 1 1 RIC1 Aminotran_1_2 PF00155.21 KPA42877.1 - 2.2e-17 63.3 0.0 3.1e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KPA42877.1 - 4.8e-08 32.2 0.0 1.2e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KPA42877.1 - 0.0044 16.4 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family p450 PF00067.22 KPA42878.1 - 1.5e-58 198.7 0.0 2.3e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.22 KPA42879.1 - 1.7e-91 307.3 0.0 2.2e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KPA42879.1 - 1.8e-31 109.6 0.1 3.3e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KPA42879.1 - 3.5e-06 27.8 0.1 4.6e-05 24.2 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 zf-CCCH_2 PF14608.6 KPA42880.1 - 4.4e-14 52.3 58.0 1.2e-05 25.6 11.8 5.6 5 1 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KPA42880.1 - 0.0014 18.9 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Amino_oxidase PF01593.24 KPA42881.1 - 5.5e-26 91.9 0.0 7.4e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA42881.1 - 7.5e-12 45.3 0.1 2.5e-11 43.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA42881.1 - 9.4e-09 35.3 0.0 5.1e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA42881.1 - 7.4e-05 22.1 0.1 0.003 16.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA42881.1 - 9.9e-05 22.8 0.0 0.061 13.9 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA42881.1 - 0.00023 20.5 0.1 0.001 18.4 0.0 1.9 2 0 0 2 2 2 1 Thi4 family MCRA PF06100.11 KPA42881.1 - 0.00097 18.0 0.3 0.067 12.0 0.0 2.1 2 0 0 2 2 2 1 MCRA family NAD_binding_9 PF13454.6 KPA42881.1 - 0.0018 18.2 0.0 0.0073 16.3 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KPA42881.1 - 0.0087 15.2 0.1 0.73 8.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KPA42881.1 - 0.01 15.2 0.8 0.23 10.7 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KPA42881.1 - 0.018 14.1 0.3 0.23 10.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KPA42881.1 - 0.12 11.4 0.0 0.3 10.1 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KPA42881.1 - 0.15 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Med14 PF08638.11 KPA42882.1 - 9.4e-64 214.4 0.0 1.6e-63 213.6 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 G6PD_C PF02781.16 KPA42883.1 - 3.8e-115 384.1 0.0 6.7e-115 383.2 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KPA42883.1 - 6.2e-60 202.9 0.1 1.1e-59 202.1 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ribosomal_L35Ae PF01247.18 KPA42884.1 - 7.6e-41 138.2 0.2 8.6e-41 138.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KPA42884.1 - 5.7e-05 23.3 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2406 PF10295.9 KPA42885.1 - 2.8e-27 95.2 0.4 1.8e-26 92.6 0.4 2.5 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) VMA21 PF09446.10 KPA42886.1 - 5.3e-07 29.6 14.2 0.001 19.1 4.8 2.1 1 1 1 2 2 2 2 VMA21-like domain DUF5325 PF17259.2 KPA42886.1 - 0.28 11.1 3.6 0.44 10.5 3.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5325) SNF2_N PF00176.23 KPA42887.1 - 4.8e-52 176.8 0.0 7.8e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA42887.1 - 2.2e-17 63.4 0.1 5.3e-17 62.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KPA42887.1 - 5.4e-06 25.8 0.0 1.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KPA42887.1 - 1.9e-05 24.8 0.0 8e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KPA42887.1 - 0.0064 15.7 2.4 0.26 10.4 1.3 2.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 HBS1_N PF08938.10 KPA42887.1 - 0.067 13.5 3.0 0.09 13.1 0.0 2.5 2 0 0 2 2 2 0 HBS1 N-terminus Myb_DNA-bind_6 PF13921.6 KPA42888.1 - 0.0019 18.4 0.2 0.0039 17.4 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain PBP1_TM PF14812.6 KPA42888.1 - 0.031 14.6 2.9 0.031 14.6 2.9 2.3 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sel1 PF08238.12 KPA42889.1 - 1.5e-38 130.4 29.3 2.6e-06 27.9 0.2 7.7 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 KPA42889.1 - 0.054 14.2 1.9 9.6 7.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Chitin_synth_2 PF03142.15 KPA42890.1 - 8.4e-291 965.1 0.1 1.1e-290 964.8 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KPA42890.1 - 7.8e-14 52.0 4.6 2.7e-13 50.3 4.6 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KPA42890.1 - 8.6e-10 38.9 0.0 7.9e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KPA42890.1 - 0.00036 20.0 0.0 0.0042 16.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KPA42890.1 - 0.0017 18.2 0.0 0.072 12.9 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Pkinase PF00069.25 KPA42891.1 - 8.9e-69 231.8 0.0 1.2e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA42891.1 - 5.9e-42 143.7 0.0 8.6e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KPA42891.1 - 4.4e-07 30.0 0.0 0.00042 20.4 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KPA42891.1 - 4.5e-06 26.2 0.0 1.3e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KPA42891.1 - 0.0006 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KPA42891.1 - 0.015 14.1 0.2 0.028 13.2 0.2 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KPA42891.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain OPA3 PF07047.12 KPA42892.1 - 7.2e-48 161.5 0.7 7.2e-48 161.5 0.7 1.7 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) Peptidase_S49_N PF08496.10 KPA42892.1 - 0.017 15.2 5.6 0.13 12.3 0.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Vpu PF00558.19 KPA42892.1 - 0.04 13.7 0.6 0.074 12.8 0.6 1.5 1 0 0 1 1 1 0 Vpu protein XhlA PF10779.9 KPA42892.1 - 0.089 13.0 7.6 0.21 11.8 7.6 1.6 1 0 0 1 1 1 0 Haemolysin XhlA MAP17 PF15807.5 KPA42892.1 - 0.12 12.6 3.0 0.18 12.0 0.2 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Serinc PF03348.15 KPA42892.1 - 0.13 11.2 0.1 0.17 10.8 0.1 1.3 1 1 0 1 1 1 0 Serine incorporator (Serinc) DUF2681 PF10883.8 KPA42892.1 - 0.15 12.5 4.9 0.19 12.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF5033 PF16436.5 KPA42892.1 - 0.15 12.0 0.2 0.37 10.7 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5033) FTCD_C PF04961.12 KPA42892.1 - 0.35 10.6 2.7 1.8 8.3 0.1 2.1 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase DUF4200 PF13863.6 KPA42892.1 - 0.59 10.6 18.5 0.37 11.2 10.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3552 PF12072.8 KPA42892.1 - 0.9 8.9 17.6 0.095 12.1 9.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Tho2 PF11262.8 KPA42892.1 - 1.1 8.4 7.4 0.83 8.8 3.0 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Spc24 PF08286.11 KPA42892.1 - 1.5 9.1 7.1 0.24 11.6 3.0 1.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 UPF0242 PF06785.11 KPA42892.1 - 2.2 8.3 11.7 0.059 13.5 3.7 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YnfE PF17452.2 KPA42892.1 - 2.5 8.5 7.5 0.37 11.1 2.7 2.0 2 0 0 2 2 2 0 Uncharacterized YnfE-like TMPIT PF07851.13 KPA42892.1 - 2.5 7.2 5.9 0.32 10.2 2.1 1.5 2 0 0 2 2 2 0 TMPIT-like protein Occludin_ELL PF07303.13 KPA42892.1 - 4 8.2 11.0 1.4 9.6 2.0 2.6 2 1 0 2 2 2 0 Occludin homology domain DUF4140 PF13600.6 KPA42892.1 - 6.9 7.2 9.1 0.78 10.2 3.0 2.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) TolA_bind_tri PF16331.5 KPA42892.1 - 9.7 6.3 13.6 0.4 10.8 6.6 2.2 2 1 0 2 2 1 0 TolA binding protein trimerisation AAA_lid_7 PF17867.1 KPA42893.1 - 0.016 15.4 0.1 0.069 13.3 0.0 1.9 2 0 0 2 2 2 0 Midasin AAA lid domain 7TMR-DISM_7TM PF07695.11 KPA42894.1 - 0.59 10.0 8.7 0.4 10.6 6.3 1.5 1 1 1 2 2 2 0 7TM diverse intracellular signalling SBDS PF01172.18 KPA42895.1 - 2.2e-24 85.4 0.2 2.6e-24 85.1 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.20 KPA42896.1 - 1.5e-22 80.7 0.0 3.5e-22 79.5 0.0 1.7 1 1 0 1 1 1 1 RhoGEF domain E1-E2_ATPase PF00122.20 KPA42897.1 - 3.5e-51 173.3 5.9 7.7e-51 172.2 1.6 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KPA42897.1 - 3.1e-25 89.7 0.3 6.5e-24 85.4 0.1 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KPA42897.1 - 1.4e-19 69.9 0.0 4.8e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KPA42897.1 - 6.8e-19 67.3 0.0 2.2e-18 65.7 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 KPA42897.1 - 0.00014 22.3 0.0 0.00033 21.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mpv17_PMP22 PF04117.12 KPA42900.1 - 2.7e-11 43.5 1.2 2.7e-11 43.5 1.2 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family YIF1 PF03878.15 KPA42901.1 - 3.6e-100 334.4 3.6 4.2e-100 334.2 3.6 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KPA42901.1 - 0.074 12.8 13.8 0.044 13.5 11.6 1.6 1 1 0 1 1 1 0 Yip1 domain SRP-alpha_N PF04086.13 KPA42902.1 - 1.6e-81 274.4 0.0 2.3e-81 273.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KPA42902.1 - 4.4e-53 179.8 0.2 7.3e-53 179.1 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KPA42902.1 - 4.4e-10 39.6 0.2 1.9e-09 37.6 0.1 2.0 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KPA42902.1 - 4.1e-05 22.7 0.0 8.1e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KPA42902.1 - 0.00024 20.9 0.1 0.00056 19.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KPA42902.1 - 0.0014 19.0 1.7 0.004 17.6 0.1 2.5 2 1 1 3 3 3 1 AAA domain CbiA PF01656.23 KPA42902.1 - 0.013 15.5 0.8 2.1 8.4 0.1 2.7 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 KPA42902.1 - 0.024 14.2 0.1 0.05 13.2 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KPA42902.1 - 0.028 14.0 0.1 0.08 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KPA42902.1 - 0.035 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KPA42902.1 - 0.04 14.3 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KPA42902.1 - 0.041 13.6 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KPA42902.1 - 0.047 13.8 0.3 0.25 11.5 0.3 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KPA42902.1 - 0.077 13.5 0.0 0.24 11.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_31 PF13614.6 KPA42902.1 - 0.097 12.6 0.1 2.1 8.2 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KPA42902.1 - 0.11 12.1 0.1 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain CENP-F_leu_zip PF10473.9 KPA42903.1 - 0.0036 17.3 7.9 0.0036 17.3 7.9 6.5 2 2 4 6 6 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PAM2 PF07145.15 KPA42903.1 - 0.29 10.9 14.5 0.38 10.6 1.3 3.9 3 0 0 3 3 3 0 Ataxin-2 C-terminal region Mid2 PF04478.12 KPA42904.1 - 1.5e-05 24.9 0.3 1.5e-05 24.9 0.3 2.4 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor PI-PLC-X PF00388.19 KPA42906.1 - 5e-55 185.1 0.0 9.3e-55 184.2 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KPA42906.1 - 3.3e-38 130.5 0.1 6.7e-38 129.6 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain zf-C2H2 PF00096.26 KPA42907.1 - 1.1e-08 35.1 14.4 0.00051 20.3 1.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KPA42907.1 - 2.1e-05 24.6 11.5 2.1e-05 24.6 11.5 2.3 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KPA42907.1 - 9.5e-05 22.7 3.5 9.5e-05 22.7 3.5 2.8 3 0 0 3 3 3 1 Zinc-finger double domain Fungal_trans PF04082.18 KPA42907.1 - 0.00048 19.2 0.1 0.00098 18.2 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KPA42907.1 - 0.002 18.8 17.8 0.04 14.8 0.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA42907.1 - 0.027 14.8 1.6 1.6 9.1 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KPA42907.1 - 0.028 14.4 8.3 0.13 12.3 2.6 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger MFS_1 PF07690.16 KPA42908.1 - 4.1e-14 52.3 34.3 6.4e-13 48.3 33.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA42908.1 - 1.8e-08 33.3 11.7 2.4e-08 32.9 11.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MtrF PF09472.10 KPA42908.1 - 0.75 9.2 5.5 5.6 6.4 1.2 3.1 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Rick_17kDa_Anti PF05433.15 KPA42908.1 - 7.5 6.5 8.7 15 5.6 0.2 2.9 2 0 0 2 2 2 0 Glycine zipper 2TM domain ketoacyl-synt PF00109.26 KPA42909.1 - 1.5e-64 218.1 0.2 3.2e-63 213.7 0.2 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KPA42909.1 - 2.3e-49 167.7 0.1 7.7e-49 166.0 0.0 1.9 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KPA42909.1 - 3.3e-44 151.7 0.0 5.7e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KPA42909.1 - 1.7e-43 149.0 0.0 2.4e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KPA42909.1 - 5.2e-36 123.2 0.1 1.1e-35 122.2 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KPA42909.1 - 7.1e-17 61.9 0.0 1.9e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KPA42909.1 - 1.6e-12 47.3 0.1 3.7e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 KPA42909.1 - 0.026 14.9 0.0 0.074 13.4 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KPA42909.1 - 0.027 13.5 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 KPA42909.1 - 0.048 13.0 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 KPA42909.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF16 PF01519.16 KPA42910.1 - 0.0027 18.2 1.5 0.0032 17.9 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF16 Fib_alpha PF08702.10 KPA42910.1 - 0.0061 16.7 0.4 0.0061 16.7 0.4 1.8 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family UME PF08064.13 KPA42910.1 - 0.11 12.4 1.0 16 5.5 0.4 2.3 2 0 0 2 2 2 0 UME (NUC010) domain SlyX PF04102.12 KPA42910.1 - 2.3 8.9 6.3 0.36 11.5 1.7 2.1 2 0 0 2 2 2 0 SlyX Glyco_hydro_31 PF01055.26 KPA42911.1 - 4.3e-115 385.4 2.5 6.3e-115 384.8 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KPA42911.1 - 0.00055 20.2 0.1 0.0031 17.8 0.1 2.3 1 1 0 1 1 1 1 Galactose mutarotase-like Fungal_trans PF04082.18 KPA42912.1 - 2.1e-07 30.3 2.2 3.5e-07 29.5 2.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KPA42913.1 - 9.8e-87 291.7 27.1 1.2e-86 291.4 27.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA42913.1 - 5.5e-21 74.9 54.6 2.3e-20 72.9 31.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PAP1 PF08601.10 KPA42914.1 - 3.7e-74 250.7 66.9 1e-55 190.0 8.0 4.8 2 2 2 4 4 4 3 Transcription factor PAP1 bZIP_1 PF00170.21 KPA42914.1 - 1.1e-08 35.0 11.4 3.8e-08 33.3 11.4 1.9 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 KPA42914.1 - 0.0099 15.6 5.6 0.0099 15.6 5.6 2.0 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 KPA42914.1 - 0.012 15.7 11.5 0.032 14.3 11.4 1.8 1 1 0 1 1 1 0 Basic region leucine zipper dsrm PF00035.26 KPA42914.1 - 0.029 15.1 0.0 0.088 13.5 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF812 PF05667.11 KPA42914.1 - 0.047 12.6 9.2 0.036 12.9 7.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) bZIP_Maf PF03131.17 KPA42914.1 - 0.048 14.2 10.1 0.16 12.5 10.1 1.9 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4618 PF15397.6 KPA42914.1 - 0.071 12.5 5.4 0.16 11.3 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF16 PF01519.16 KPA42914.1 - 0.18 12.3 3.8 2.3 8.8 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 KPA42914.1 - 0.19 12.3 1.2 0.63 10.7 1.2 1.9 1 0 0 1 1 1 0 SlyX EMP24_GP25L PF01105.24 KPA42914.1 - 0.21 11.5 3.3 0.41 10.6 3.3 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TMPIT PF07851.13 KPA42914.1 - 3.8 6.7 8.2 5.6 6.1 1.4 2.2 2 0 0 2 2 2 0 TMPIT-like protein CDC45 PF02724.14 KPA42914.1 - 4.7 5.4 11.1 7.5 4.7 11.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Wbp11 PF09429.10 KPA42915.1 - 4.2e-23 81.5 15.9 4.2e-23 81.5 15.9 2.4 3 0 0 3 3 3 1 WW domain binding protein 11 Lipoprotein_7 PF01540.16 KPA42915.1 - 0.002 17.5 2.9 0.0032 16.8 2.9 1.2 1 0 0 1 1 1 1 Adhesin lipoprotein Mcm10 PF09332.11 KPA42915.1 - 0.45 9.9 8.9 0.13 11.7 2.9 2.0 2 0 0 2 2 2 0 Mcm10 replication factor MFS_1 PF07690.16 KPA42916.1 - 9.7e-35 120.1 69.1 4e-34 118.1 49.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA42916.1 - 1.4e-06 27.5 37.0 0.00014 20.9 13.9 3.1 2 1 0 2 2 2 2 Sugar (and other) transporter DFP PF04127.15 KPA42917.1 - 1.1e-13 51.4 0.0 5.6e-06 26.3 0.0 3.2 1 1 2 3 3 3 3 DNA / pantothenate metabolism flavoprotein Acatn PF13000.7 KPA42918.1 - 3.2e-160 534.2 18.3 9e-82 275.3 8.6 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.10 KPA42919.1 - 3e-63 213.7 0.1 6.9e-63 212.5 0.0 1.6 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Malate_DH PF12434.8 KPA42919.1 - 0.23 11.5 0.3 0.23 11.5 0.3 2.2 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Yae1_N PF09811.9 KPA42920.1 - 1.4e-13 50.3 1.0 2.6e-13 49.4 1.0 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal SNCAIP_SNCA_bd PF16700.5 KPA42920.1 - 0.17 11.6 0.4 0.36 10.6 0.4 1.5 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain Zn_clus PF00172.18 KPA42921.1 - 0.0026 17.8 3.5 0.0045 17.1 3.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KPA42922.1 - 3.6e-34 118.3 0.0 9.5e-34 116.9 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 MFS_1 PF07690.16 KPA42923.1 - 1.4e-40 139.3 32.0 5.8e-39 134.0 18.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA42923.1 - 7.7e-10 38.2 3.8 7.7e-10 38.2 3.8 1.8 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KPA42923.1 - 0.00087 18.2 0.2 0.0063 15.4 0.2 2.6 1 1 0 1 1 1 1 MFS_1 like family GTP_EFTU PF00009.27 KPA42924.1 - 3.2e-54 183.4 0.0 4.7e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KPA42924.1 - 8.7e-41 138.7 0.0 2.2e-40 137.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KPA42924.1 - 9.7e-15 54.7 2.6 1.2e-14 54.4 1.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KPA42924.1 - 0.0017 18.4 0.1 0.032 14.3 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KPA42924.1 - 0.015 15.2 0.6 0.042 13.7 0.6 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 SLS PF14611.6 KPA42925.1 - 5.1e-25 88.6 0.1 1.3e-24 87.2 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator MAGE PF01454.19 KPA42926.1 - 6.5e-64 215.5 1.2 6.8e-64 215.5 0.0 1.5 2 0 0 2 2 2 1 MAGE family SF3b10 PF07189.11 KPA42927.1 - 7.5e-38 128.5 0.0 8.5e-38 128.3 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) zf-MYND PF01753.18 KPA42928.1 - 0.0071 16.4 1.4 0.0071 16.4 1.4 3.8 4 0 0 4 4 4 3 MYND finger zf-C6H2 PF15801.5 KPA42928.1 - 0.012 15.9 1.8 0.012 15.9 1.8 3.4 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding RRM_1 PF00076.22 KPA42929.1 - 4.3e-16 58.5 0.0 1.1e-11 44.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.25 KPA42930.1 - 1.9e-28 99.3 0.0 2.9e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA42930.1 - 1.1e-23 84.1 0.0 1.5e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA42930.1 - 0.00066 19.6 0.0 0.0074 16.2 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KPA42930.1 - 0.0027 17.2 0.0 0.046 13.2 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ras PF00071.22 KPA42931.1 - 6.7e-51 172.1 0.0 7.8e-51 171.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA42931.1 - 3e-18 66.2 0.0 4.2e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA42931.1 - 1.4e-09 37.7 0.0 1.6e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPA42931.1 - 5e-05 22.9 0.1 0.00051 19.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPA42931.1 - 7.1e-05 22.8 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KPA42931.1 - 0.0012 18.9 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KPA42931.1 - 0.057 13.8 0.2 0.13 12.6 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KPA42931.1 - 0.064 12.4 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KPA42931.1 - 0.098 12.9 0.2 1.1 9.5 0.1 2.5 1 1 1 2 2 2 0 AAA domain Scytalone_dh PF02982.14 KPA42931.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase Nif11 PF07862.11 KPA42931.1 - 0.15 12.3 0.0 0.4 11.0 0.0 1.8 1 1 0 1 1 1 0 Nif11 domain AAA_25 PF13481.6 KPA42931.1 - 0.35 10.4 1.3 6 6.4 1.3 2.6 1 1 0 1 1 1 0 AAA domain HET PF06985.11 KPA42934.1 - 2.8e-13 50.5 0.1 5.3e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) bZIP_2 PF07716.15 KPA42935.1 - 0.12 12.4 15.4 0.21 11.7 15.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 KPA42935.1 - 0.19 11.8 10.6 0.3 11.2 10.6 1.2 1 0 0 1 1 1 0 bZIP transcription factor PspB PF06667.12 KPA42935.1 - 1.9 8.6 3.8 3.4 7.8 3.8 1.4 1 0 0 1 1 1 0 Phage shock protein B SGL PF08450.12 KPA42936.1 - 2.9e-62 210.4 0.0 3.4e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 KPA42936.1 - 0.0067 16.3 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat Lactonase PF10282.9 KPA42936.1 - 0.065 12.5 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 KPA42936.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Arylesterase ATP-synt_DE_N PF02823.16 KPA42938.1 - 4.9e-18 64.8 0.1 7.3e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2457 PF10446.9 KPA42939.1 - 6.8e-169 562.9 31.9 6.8e-169 562.9 31.9 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) TFIIA PF03153.13 KPA42939.1 - 0.0079 16.2 24.7 0.023 14.7 24.7 1.7 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 KPA42939.1 - 0.021 13.1 22.9 0.035 12.3 22.9 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KPA42939.1 - 6.5 6.1 33.6 0.056 12.9 25.4 1.7 2 0 0 2 2 2 0 SDA1 Arf PF00025.21 KPA42940.1 - 5.6e-66 221.3 0.0 6.2e-66 221.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KPA42940.1 - 8e-10 38.4 0.1 2.8e-06 26.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KPA42940.1 - 1.1e-07 31.6 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KPA42940.1 - 1.3e-07 31.3 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KPA42940.1 - 1.8e-07 31.4 0.0 6.1e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KPA42940.1 - 3.3e-07 30.4 0.0 4.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KPA42940.1 - 6.3e-06 25.7 0.0 7.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KPA42940.1 - 0.0095 15.5 0.1 0.39 10.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain CENP-M PF11111.8 KPA42940.1 - 0.1 11.8 0.0 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 Centromere protein M (CENP-M) cobW PF02492.19 KPA42940.1 - 0.18 11.4 0.0 9.1 5.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3336 PF11815.8 KPA42941.1 - 5e-49 165.6 5.1 7.9e-49 164.9 5.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KPA42941.1 - 6.9e-18 65.6 0.0 3.5e-17 63.3 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase DnaJ PF00226.31 KPA42942.1 - 1.4e-14 53.9 0.8 4e-14 52.5 0.8 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KPA42942.1 - 1.7e-08 34.0 0.0 3.1e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DUF2347 PF09804.9 KPA42943.1 - 3.8e-108 361.4 0.0 5e-108 361.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KPA42943.1 - 4.9e-65 219.5 0.0 8.3e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.10 KPA42943.1 - 0.00051 20.0 0.0 0.0012 18.8 0.0 1.5 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KPA42943.1 - 0.066 11.9 0.1 2.4 6.8 0.0 2.7 3 1 0 4 4 4 0 Transport protein Avl9 Acyltransferase PF01553.21 KPA42944.1 - 1e-32 112.6 0.0 1.5e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.21 KPA42944.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP ABC2_membrane_3 PF12698.7 KPA42944.1 - 0.57 9.2 8.7 0.94 8.5 8.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4045 PF13254.6 KPA42945.1 - 1.3e-82 278.7 48.4 1.3e-82 278.7 48.4 7.1 3 3 1 5 5 5 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KPA42945.1 - 1.1e-08 34.8 0.0 0.0029 17.5 0.0 3.8 3 0 0 3 3 3 2 Gelsolin repeat Arf PF00025.21 KPA42946.1 - 1.2e-66 223.4 0.6 1.4e-66 223.3 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KPA42946.1 - 4.1e-12 46.0 0.0 4.8e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA42946.1 - 5e-12 46.1 0.1 7.1e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KPA42946.1 - 8.4e-12 44.9 0.9 1e-06 28.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KPA42946.1 - 4.2e-10 39.4 0.0 5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KPA42946.1 - 2.3e-07 30.4 0.0 2.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPA42946.1 - 2.6e-07 30.7 0.0 3.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPA42946.1 - 0.00014 21.4 0.0 0.0013 18.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KPA42946.1 - 0.035 13.6 0.2 0.079 12.5 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 KPA42946.1 - 0.1 12.1 0.1 1.4 8.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KPA42946.1 - 0.16 12.0 0.0 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Acetyltransf_1 PF00583.25 KPA42947.1 - 0.011 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA42947.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KPA42949.1 - 4.8e-51 173.6 0.0 1.2e-50 172.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA42949.1 - 8.6e-20 71.1 0.0 4.1e-19 68.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA42949.1 - 0.065 12.5 0.4 5.7 6.2 0.1 2.4 2 0 0 2 2 2 0 Kinase-like TFIIA PF03153.13 KPA42949.1 - 8 6.3 10.7 13 5.7 10.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mtc PF03820.17 KPA42950.1 - 1.2e-111 372.7 0.0 1.4e-111 372.5 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Lactamase_B_4 PF13691.6 KPA42951.1 - 1.3e-21 76.1 0.0 9e-21 73.3 0.0 2.2 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KPA42951.1 - 3.6e-16 59.3 0.2 7.7e-16 58.2 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KPA42951.1 - 0.00015 21.8 0.2 0.00034 20.7 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Flavin_Reduct PF01613.18 KPA42952.1 - 5.2e-20 72.1 0.0 7.5e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 KPA42952.1 - 0.18 11.6 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) PDEase_II PF02112.15 KPA42953.1 - 1e-53 182.6 0.0 9.3e-45 153.2 0.0 3.0 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KPA42953.1 - 0.034 14.2 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily CK1gamma_C PF12605.8 KPA42954.1 - 0.04 15.1 4.0 0.04 15.1 4.0 2.9 3 0 0 3 3 3 0 Casein kinase 1 gamma C terminal AMP-binding PF00501.28 KPA42955.1 - 5.7e-67 226.2 0.0 1.8e-36 125.7 0.0 4.4 3 2 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 KPA42955.1 - 3.5e-12 47.1 0.0 9.5e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 KPA42955.1 - 0.03 14.3 1.5 0.076 13.0 1.5 1.6 1 0 0 1 1 1 0 Gas vesicle protein G DUF2183 PF09949.9 KPA42956.1 - 2.3e-31 108.1 0.0 6.3e-31 106.6 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KPA42956.1 - 0.033 13.7 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) HMGL-like PF00682.19 KPA42957.1 - 3.1e-75 253.1 0.0 4.4e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KPA42957.1 - 7.4e-22 77.7 0.0 1.7e-21 76.5 0.0 1.6 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Baculo_PEP_C PF04513.12 KPA42958.1 - 5.6e-07 29.7 9.3 6.3e-05 23.0 0.0 2.8 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus DEAD PF00270.29 KPA42959.1 - 1.7e-46 158.2 0.0 3.8e-46 157.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA42959.1 - 1.1e-28 99.7 0.2 3.8e-28 98.0 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KPA42959.1 - 0.001 18.0 1.3 0.0051 15.6 0.0 2.5 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 EB1 PF03271.17 KPA42960.1 - 6.4e-18 64.7 1.2 1.2e-17 63.9 1.2 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KPA42960.1 - 6.6e-06 26.3 0.2 1.2e-05 25.4 0.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 KPA42960.1 - 0.023 14.8 0.2 0.041 14.0 0.2 1.5 1 1 0 1 1 1 0 CH-like domain in sperm protein PX PF00787.24 KPA42961.1 - 1.1e-13 51.2 0.0 2.5e-13 50.0 0.0 1.6 2 0 0 2 2 2 1 PX domain Orbi_VP5 PF00901.17 KPA42961.1 - 0.03 12.7 0.0 0.046 12.1 0.0 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF745 PF05335.13 KPA42961.1 - 0.098 12.4 3.3 0.15 11.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF3138 PF11336.8 KPA42961.1 - 0.34 9.5 0.0 0.34 9.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Thioredoxin PF00085.20 KPA42963.1 - 2.5e-24 85.2 0.0 3.2e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KPA42963.1 - 4.8e-08 33.4 0.1 1.4e-07 31.9 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KPA42963.1 - 4.2e-06 26.3 0.1 6.1e-06 25.8 0.0 1.3 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KPA42963.1 - 4.4e-06 26.5 0.1 6.3e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KPA42963.1 - 5.8e-06 26.5 0.0 9.7e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KPA42963.1 - 5.8e-06 26.2 0.0 1.4e-05 25.0 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KPA42963.1 - 4.5e-05 23.5 0.0 7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KPA42963.1 - 0.0041 17.0 0.0 0.0064 16.3 0.0 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KPA42963.1 - 0.0045 16.8 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KPA42963.1 - 0.0052 16.7 0.0 0.0083 16.1 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 KPA42963.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin ADH_zinc_N PF00107.26 KPA42964.1 - 2.1e-08 34.2 0.0 3.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA42964.1 - 1.1e-07 31.7 0.1 1.6e-06 27.9 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KPA42964.1 - 4.4e-05 23.3 0.0 7.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase MFS_1 PF07690.16 KPA42965.1 - 2.5e-23 82.6 30.0 2.5e-23 82.6 30.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA42965.1 - 1.1e-10 41.0 22.3 1.7e-08 33.8 11.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KPA42965.1 - 2.2e-06 26.4 6.1 3.7e-06 25.7 6.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PAP2 PF01569.21 KPA42966.1 - 0.21 11.4 9.9 1 9.1 2.2 3.3 3 1 0 3 3 3 0 PAP2 superfamily NUDIX PF00293.28 KPA42967.1 - 6.3e-11 42.4 0.0 9.3e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ANAPC4_WD40 PF12894.7 KPA42968.1 - 3.9e-07 30.3 0.0 0.0061 16.8 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KPA42968.1 - 5.6e-06 25.9 0.0 1.3e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 WD40-like domain WD40 PF00400.32 KPA42968.1 - 6.2e-06 26.9 1.2 0.097 13.6 0.1 5.4 5 1 0 5 5 5 1 WD domain, G-beta repeat TruB_C PF09142.11 KPA42968.1 - 0.0004 20.1 0.3 45 3.9 0.0 5.1 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal PD40 PF07676.12 KPA42968.1 - 0.003 17.4 0.1 6.9 6.7 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KPA42968.1 - 0.12 11.3 0.2 5 6.0 0.0 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5122 PF17164.4 KPA42968.1 - 0.39 11.1 1.8 35 4.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller ADH_N PF08240.12 KPA42969.1 - 3.8e-25 87.9 3.4 6.3e-25 87.2 3.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA42969.1 - 9.5e-16 58.0 0.0 2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPA42969.1 - 0.00023 20.6 0.3 0.0004 19.8 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KPA42969.1 - 0.0059 15.9 0.1 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KPA42969.1 - 0.15 11.7 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3180 PF11377.8 KPA42970.1 - 0.038 14.1 1.7 0.065 13.4 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) DUF21 PF01595.20 KPA42970.1 - 0.12 12.0 0.3 0.12 12.0 0.3 2.0 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain IBR PF01485.21 KPA42971.1 - 0.011 15.9 1.4 0.011 15.9 1.4 1.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-CCHC_4 PF14392.6 KPA42971.1 - 0.043 13.5 7.6 1.2 9.0 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle Pectate_lyase_3 PF12708.7 KPA42972.1 - 4.1e-91 304.6 9.6 6.5e-78 261.5 3.5 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KPA42972.1 - 2.1e-06 27.3 2.7 0.011 15.4 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase KaiB PF07689.12 KPA42972.1 - 0.073 12.8 1.4 0.11 12.2 0.2 1.9 2 0 0 2 2 2 0 KaiB domain WD40 PF00400.32 KPA42973.1 - 7.4e-36 121.6 13.6 4e-07 30.6 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KPA42973.1 - 7.3e-10 38.6 0.4 1.5e-09 37.6 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA42973.1 - 2.9e-08 33.4 0.1 5.3e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KPA42973.1 - 5.7e-08 33.0 0.1 0.021 15.1 0.0 5.4 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA42973.1 - 1e-05 24.4 0.8 0.38 9.3 0.0 3.9 1 1 3 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KPA42973.1 - 0.018 13.8 0.2 9.1 4.9 0.1 3.3 3 1 0 3 3 3 0 Nup133 N terminal like PQQ_2 PF13360.6 KPA42973.1 - 0.038 13.6 0.1 0.22 11.1 0.0 2.1 1 1 1 2 2 2 0 PQQ-like domain Ge1_WD40 PF16529.5 KPA42973.1 - 0.046 12.7 0.1 0.43 9.5 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FlaG PF03646.15 KPA42973.1 - 0.061 13.5 0.0 14 5.9 0.0 3.4 4 0 0 4 4 4 0 FlaG protein Cytochrom_D1 PF02239.16 KPA42973.1 - 0.076 11.5 0.0 0.18 10.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome D1 heme domain Frtz PF11768.8 KPA42973.1 - 0.21 9.9 0.1 1.6 6.9 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Scs3p PF10261.9 KPA42974.1 - 5.6e-75 252.0 7.3 7.1e-75 251.7 7.3 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM M20_dimer PF07687.14 KPA42975.1 - 1.6e-07 31.2 0.0 4.3e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KPA42975.1 - 7.2e-06 25.8 0.1 1.1e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cupin_1 PF00190.22 KPA42976.1 - 4.8e-37 126.9 0.2 1.8e-17 63.4 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KPA42976.1 - 2.4e-22 78.4 0.1 1.3e-11 44.0 0.1 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KPA42976.1 - 2.3e-06 27.2 0.2 0.002 17.8 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KPA42976.1 - 4.6e-05 23.4 0.0 0.001 19.0 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 KPA42976.1 - 0.00016 21.6 0.0 0.0023 17.9 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain 3-HAO PF06052.12 KPA42976.1 - 0.0012 18.5 0.0 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Auxin_BP PF02041.16 KPA42976.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Auxin binding protein DUF4397 PF14344.6 KPA42976.1 - 0.14 13.0 0.0 0.26 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4397) Tubulin PF00091.25 KPA42977.1 - 3.3e-68 229.8 0.0 4.8e-68 229.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KPA42977.1 - 1.4e-37 128.6 0.0 2.1e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KPA42977.1 - 2.8e-06 27.6 0.0 6.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KPA42977.1 - 0.0019 17.9 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KPA42977.1 - 0.002 17.4 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin like PRESAN PF09687.10 KPA42977.1 - 0.12 13.0 0.4 17 6.0 0.0 2.9 3 0 0 3 3 3 0 Plasmodium RESA N-terminal Egh16-like PF11327.8 KPA42978.1 - 1.9e-51 175.1 10.7 1.9e-51 175.1 10.7 1.9 2 0 0 2 2 2 1 Egh16-like virulence factor Izumo-Ig PF16706.5 KPA42978.1 - 0.016 15.3 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain I-set PF07679.16 KPA42978.1 - 0.047 13.7 0.2 0.1 12.7 0.2 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain Spore-coat_CotD PF11122.8 KPA42978.1 - 0.29 12.0 3.7 0.82 10.5 0.4 2.5 1 1 1 2 2 2 0 Inner spore coat protein D Aa_trans PF01490.18 KPA42980.1 - 1.6e-51 175.4 32.0 1.8e-51 175.2 32.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Lipase_GDSL_2 PF13472.6 KPA42983.1 - 5e-11 43.3 0.1 6.6e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA42983.1 - 4.8e-09 36.5 0.0 6.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NIF PF03031.18 KPA42984.1 - 1.2e-40 138.8 0.1 1.9e-40 138.2 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase OapA PF04225.12 KPA42984.1 - 0.17 12.0 0.1 0.34 11.0 0.1 1.4 1 0 0 1 1 1 0 Opacity-associated protein A LysM-like domain Vta1 PF04652.16 KPA42986.1 - 7.4e-49 165.5 4.6 1.2e-48 164.8 1.3 2.0 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KPA42986.1 - 8.5e-18 63.8 0.4 1.7e-17 62.8 0.4 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain Thioredoxin PF00085.20 KPA42987.1 - 6.7e-31 106.3 0.1 4.4e-26 90.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KPA42987.1 - 2.4e-08 34.1 0.0 2.7e-05 24.1 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KPA42987.1 - 1.8e-07 31.6 0.1 0.004 17.6 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KPA42987.1 - 3.6e-07 29.8 0.0 3.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KPA42987.1 - 3.8e-05 23.9 0.0 35 4.8 0.0 5.0 3 2 2 5 5 5 0 Thioredoxin-like ERp29_N PF07912.13 KPA42987.1 - 0.0016 18.6 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 2 ERp29, N-terminal domain TraF PF13728.6 KPA42987.1 - 0.007 16.2 0.0 0.007 16.2 0.0 4.1 4 0 0 4 4 4 2 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KPA42987.1 - 0.017 15.2 0.2 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain AhpC-TSA PF00578.21 KPA42987.1 - 0.028 14.3 0.0 0.19 11.7 0.0 2.3 3 0 0 3 3 3 0 AhpC/TSA family Thioredoxin_7 PF13899.6 KPA42987.1 - 0.06 13.5 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like RNase_PH PF01138.21 KPA42988.1 - 2.5e-36 125.1 0.2 3.9e-36 124.5 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Ring_hydroxyl_A PF00848.19 KPA42988.1 - 0.16 11.9 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) ADH_N PF08240.12 KPA42989.1 - 7.2e-29 99.9 2.4 2.7e-28 98.0 2.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA42989.1 - 7.2e-20 71.3 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA42989.1 - 0.00011 23.3 0.0 0.00023 22.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPA42989.1 - 0.00032 20.2 0.2 0.00054 19.5 0.2 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KPA42989.1 - 0.023 14.0 0.4 0.04 13.2 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LOR PF04525.12 KPA42990.1 - 2.1e-23 82.9 0.6 2.4e-23 82.7 0.6 1.0 1 0 0 1 1 1 1 LURP-one-related Glyco_hydro_17 PF00332.18 KPA42991.1 - 1.2e-08 35.0 0.5 1.7e-08 34.4 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 HEPN_LA2681 PF18733.1 KPA42991.1 - 0.16 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 LA2681-like HEPN SPX PF03105.19 KPA42991.1 - 1.8 8.4 13.5 2.7 7.8 13.5 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 KPA42991.1 - 4.5 5.7 12.7 6.4 5.2 12.7 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 KPA42991.1 - 5.6 6.1 16.4 7.8 5.6 16.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Sugar_tr PF00083.24 KPA42992.1 - 2.1e-69 234.6 23.9 2.5e-69 234.3 23.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA42992.1 - 5.2e-19 68.4 25.3 5.2e-19 68.4 25.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPA42992.1 - 0.001 18.0 3.1 0.001 18.0 3.1 2.0 2 0 0 2 2 2 1 MFS_1 like family Phage_holin_2_4 PF16082.5 KPA42992.1 - 0.039 13.7 0.9 0.16 11.7 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Fungal_trans PF04082.18 KPA42993.1 - 1e-56 191.9 0.2 1.7e-56 191.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPA42993.1 - 7.3e-07 29.3 11.7 0.0011 19.3 2.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA42993.1 - 0.0024 18.6 9.3 0.042 14.7 2.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger ADK_lid PF05191.14 KPA42993.1 - 0.23 11.5 1.6 0.51 10.4 1.6 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid Ogr_Delta PF04606.12 KPA42993.1 - 0.38 10.8 3.8 4.3 7.4 0.2 2.5 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger Cytochrom_C PF00034.21 KPA42993.1 - 0.42 11.8 3.0 22 6.3 0.0 4.2 3 2 1 4 4 4 0 Cytochrome c zf-H2C2_2 PF13465.6 KPA42993.1 - 0.55 10.8 5.7 0.095 13.2 1.4 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf_Hakai PF18408.1 KPA42993.1 - 1.8 8.3 8.8 1.2 8.9 1.0 3.1 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain DUF2070 PF09843.9 KPA42994.1 - 8.7 4.5 8.2 12 4.1 8.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Fungal_trans PF04082.18 KPA42995.1 - 1e-13 50.9 0.0 3.9e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA42995.1 - 4.7e-09 36.2 9.1 7.5e-09 35.6 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KPA42996.1 - 9.6e-48 162.8 0.1 1.1e-47 162.5 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA42996.1 - 1e-13 51.6 0.0 1.5e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KPA42996.1 - 1.2e-05 24.5 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPA42996.1 - 9.3e-05 22.0 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KPA42996.1 - 0.0057 16.9 0.0 0.0096 16.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 KPA42996.1 - 0.03 13.7 0.1 0.078 12.4 0.1 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KPA42996.1 - 0.12 12.8 0.1 0.56 10.7 0.0 2.3 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KPA42997.1 - 2.9e-63 214.4 0.3 3.4e-63 214.2 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA42997.1 - 7e-10 39.0 1.4 1.5e-09 37.9 1.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA42997.1 - 4.7e-07 29.9 0.2 1.5e-06 28.4 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPA42997.1 - 4.4e-05 22.4 0.7 0.035 12.8 0.0 3.1 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 KPA42997.1 - 0.00017 21.1 0.1 0.00029 20.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KPA42997.1 - 0.00045 19.4 1.4 0.028 13.5 0.3 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KPA42997.1 - 0.0013 18.0 1.8 0.012 14.8 0.7 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA42997.1 - 0.0058 15.9 0.1 0.01 15.1 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KPA42997.1 - 0.11 11.7 0.2 0.49 9.6 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KPA42997.1 - 0.15 12.7 1.3 0.59 10.7 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA42997.1 - 0.16 11.0 0.6 1.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Gpr1_Fun34_YaaH PF01184.19 KPA42998.1 - 4.6e-84 281.1 17.1 5.4e-84 280.9 17.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Glyco_tranf_2_3 PF13641.6 KPA42999.1 - 0.00016 21.6 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_hydro_26 PF02156.15 KPA42999.1 - 0.0062 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 MFS_1 PF07690.16 KPA43000.1 - 8.8e-27 93.9 54.2 7.9e-17 61.2 26.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA43000.1 - 5.5e-07 28.5 39.0 1.4e-06 27.1 16.7 3.1 1 1 2 3 3 3 3 MFS/sugar transport protein GTP_EFTU_D4 PF14578.6 KPA43000.1 - 0.078 12.9 0.8 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 4 NIBRIN_BRCT_II PF16508.5 KPA43001.1 - 7.2e-37 126.3 0.0 1.9e-36 125.0 0.0 1.8 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein RTT107_BRCT_5 PF16770.5 KPA43001.1 - 1.1e-05 25.3 0.0 1.1e-05 25.3 0.0 2.4 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 KPA43001.1 - 0.00032 21.0 0.3 0.00082 19.7 0.1 1.8 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain FHA PF00498.26 KPA43001.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 FHA domain Cyt-b5 PF00173.28 KPA43002.1 - 1e-15 57.6 0.0 1.6e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DnaJ-X PF14308.6 KPA43004.1 - 3.7e-78 261.8 1.7 3.7e-78 261.8 1.7 3.1 4 0 0 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.31 KPA43004.1 - 9.3e-26 89.7 0.5 3.1e-25 88.1 0.5 2.0 1 0 0 1 1 1 1 DnaJ domain SQS_PSY PF00494.19 KPA43005.1 - 3e-39 135.1 0.0 3.8e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Peptidase_S8 PF00082.22 KPA43006.1 - 5.1e-34 117.9 6.9 1.1e-33 116.8 6.9 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KPA43006.1 - 0.00077 20.1 0.4 0.0015 19.2 0.4 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Methyltransf_24 PF13578.6 KPA43007.1 - 1.7e-13 51.5 0.0 2.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KPA43007.1 - 5.5e-08 32.3 0.0 7.6e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase CmcI PF04989.12 KPA43007.1 - 0.025 14.2 0.0 0.091 12.4 0.0 1.9 2 1 1 3 3 3 0 Cephalosporin hydroxylase F-box-like PF12937.7 KPA43008.1 - 0.00044 20.1 0.5 0.017 15.0 0.2 3.1 2 1 0 2 2 2 1 F-box-like Mannosyl_trans PF05007.13 KPA43009.1 - 7.9e-79 265.2 13.4 1e-78 264.8 13.4 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KPA43009.1 - 2.8e-11 43.1 13.9 1.2e-10 41.0 13.9 1.9 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Translin PF01997.16 KPA43010.1 - 1.4e-63 214.7 0.0 1.6e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Translin family Chal_sti_synt_C PF02797.15 KPA43010.1 - 0.077 13.0 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain SspP PF08179.12 KPA43011.1 - 0.13 12.7 2.7 0.19 12.2 2.7 1.2 1 0 0 1 1 1 0 Small acid-soluble spore protein P family MnmE_helical PF12631.7 KPA43013.1 - 0.013 15.7 3.1 0.026 14.7 3.1 1.5 1 0 0 1 1 1 0 MnmE helical domain YcaO PF02624.16 KPA43013.1 - 0.11 11.7 0.1 0.21 10.8 0.1 1.4 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Allexi_40kDa PF05549.11 KPA43013.1 - 0.98 8.9 7.1 0.11 12.0 2.0 1.8 2 1 1 3 3 3 0 Allexivirus 40kDa protein YgaB PF14182.6 KPA43013.1 - 2.7 8.4 6.0 0.67 10.4 0.9 2.7 3 1 0 3 3 3 0 YgaB-like protein Fib_alpha PF08702.10 KPA43013.1 - 2.9 8.1 7.8 9.5 6.4 1.9 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HEPN_AbiA_CTD PF18732.1 KPA43013.1 - 3.7 7.5 4.9 43 4.0 0.9 2.9 3 0 0 3 3 3 0 HEPN like, Abia C-terminal domain EF-hand_1 PF00036.32 KPA43015.1 - 1.1e-10 40.3 7.2 3.4e-05 23.1 0.3 4.0 3 0 0 3 3 3 2 EF hand ZZ PF00569.17 KPA43015.1 - 5.6e-10 38.9 7.7 1e-09 38.1 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.6 KPA43015.1 - 6.9e-08 31.8 7.4 8.1e-05 22.3 0.4 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KPA43015.1 - 1.3e-07 32.0 6.4 6.1e-06 26.6 3.8 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 KPA43015.1 - 0.00079 19.2 6.3 0.044 13.6 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 KPA43015.1 - 0.0022 17.9 0.0 0.0072 16.3 0.0 2.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand CAF-1_p60_C PF15512.6 KPA43015.1 - 0.0089 16.5 1.2 0.023 15.2 1.2 1.6 1 0 0 1 1 1 1 Chromatin assembly factor complex 1 subunit p60, C-terminal EF-hand_5 PF13202.6 KPA43015.1 - 4.1 7.1 10.8 0.73 9.4 0.4 3.9 4 0 0 4 4 4 0 EF hand HIG_1_N PF04588.13 KPA43016.1 - 6.7e-23 80.7 0.5 6.7e-23 80.7 0.5 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region O-ag_pol_Wzy PF14296.6 KPA43016.1 - 0.15 10.7 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy Presenilin PF01080.17 KPA43016.1 - 4.1 6.1 4.8 5.6 5.6 4.8 1.3 1 0 0 1 1 1 0 Presenilin AAA_23 PF13476.6 KPA43016.1 - 7 7.1 10.8 0.42 11.1 4.8 1.9 2 0 0 2 2 2 0 AAA domain TLD PF07534.16 KPA43017.1 - 7.7e-30 103.9 0.0 1.7e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 KPA43017.1 - 4.5e-12 46.8 3.1 6.4e-12 46.3 1.1 2.3 2 0 0 2 2 2 1 Domain of unknown function MLTR_LBD PF17765.1 KPA43018.1 - 1.1e-05 25.6 0.0 17 5.5 0.0 5.1 2 2 3 5 5 5 2 MmyB-like transcription regulator ligand binding domain DUF2314 PF10077.9 KPA43018.1 - 0.027 14.5 2.3 40 4.3 0.1 3.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2314) O_Spanin_T7 PF17531.2 KPA43018.1 - 0.046 13.7 0.4 30 4.8 0.1 3.7 3 0 0 3 3 3 0 outer-membrane spanin sub-unit 3-alpha PF03475.14 KPA43018.1 - 0.39 10.6 1.6 41 4.2 0.0 3.6 3 0 0 3 3 3 0 3-alpha domain NDUF_B4 PF07225.12 KPA43018.1 - 0.52 10.2 6.3 12 5.8 0.0 4.7 5 0 0 5 5 5 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) TctC PF03401.14 KPA43018.1 - 0.93 8.5 3.4 3.4 6.7 0.1 3.2 4 1 1 5 5 5 0 Tripartite tricarboxylate transporter family receptor Abhydrolase_6 PF12697.7 KPA43020.1 - 7.9e-12 46.2 3.3 7.9e-12 46.2 3.3 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA43020.1 - 3.1e-11 43.4 0.2 4.5e-11 42.9 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA43020.1 - 2.4e-09 36.8 1.2 3.8e-09 36.2 1.2 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KPA43020.1 - 0.00013 21.9 0.4 0.0002 21.3 0.4 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KPA43020.1 - 0.00037 20.2 0.1 0.00065 19.4 0.1 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Cutinase PF01083.22 KPA43020.1 - 0.0053 16.7 0.1 0.0084 16.1 0.1 1.2 1 0 0 1 1 1 1 Cutinase DUF818 PF05677.12 KPA43020.1 - 0.029 13.3 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) MNHE PF01899.16 KPA43020.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit Abhydrolase_2 PF02230.16 KPA43020.1 - 0.09 12.6 0.2 0.25 11.1 0.1 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KPA43020.1 - 0.11 12.0 0.7 0.35 10.3 0.6 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Lipase PF00151.19 KPA43020.1 - 0.21 10.8 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipase NMT_C PF02799.15 KPA43021.1 - 5.2e-83 277.7 1.0 6.6e-83 277.3 0.1 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KPA43021.1 - 4.9e-72 241.0 0.2 1.3e-70 236.4 0.0 2.2 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KPA43021.1 - 0.00016 21.8 0.1 0.00093 19.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Drc1-Sld2 PF11719.8 KPA43021.1 - 0.072 12.6 7.4 0.12 11.9 7.4 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Acetyltransf_3 PF13302.7 KPA43021.1 - 0.084 13.5 0.1 0.36 11.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RNA_polI_A34 PF08208.11 KPA43021.1 - 2.5 8.1 15.7 4 7.5 15.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Coilin_N PF15862.5 KPA43021.1 - 6.4 6.6 8.5 44 3.9 8.5 2.4 2 0 0 2 2 2 0 Coilin N-terminus Hydrolase_4 PF12146.8 KPA43022.1 - 1.2e-14 54.2 0.0 4.3e-14 52.4 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA43022.1 - 9.9e-12 45.0 0.0 8.8e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA43022.1 - 1.9e-10 41.8 0.0 2.4e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPA43022.1 - 0.021 14.3 0.0 0.93 8.9 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 KPA43022.1 - 0.023 14.8 0.0 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain GRDA PF04723.14 KPA43022.1 - 0.033 14.0 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A DUF2048 PF09752.9 KPA43022.1 - 0.093 11.8 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Ribophorin_II PF05817.14 KPA43023.1 - 2.1e-30 105.9 0.1 2.8e-30 105.5 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Acetyltransf_2 PF00797.17 KPA43024.1 - 4.7e-36 124.8 0.0 9.2e-36 123.8 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 KPA43024.1 - 0.027 14.9 0.2 0.33 11.4 0.0 2.2 2 0 0 2 2 2 0 Transglutaminase-like superfamily Peptidase_M28 PF04389.17 KPA43025.1 - 6.3e-34 117.4 0.0 8.6e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 CDP-OH_P_transf PF01066.21 KPA43026.1 - 4.2e-15 56.3 0.3 4.2e-15 56.3 0.3 2.9 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Alpha_GJ PF03229.13 KPA43027.1 - 0.029 14.9 3.6 0.029 14.9 3.6 1.8 2 1 0 2 2 2 0 Alphavirus glycoprotein J PX PF00787.24 KPA43028.1 - 5.9e-20 71.3 0.0 1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 PX domain IQ PF00612.27 KPA43029.1 - 0.00097 18.7 0.4 0.0034 17.0 0.4 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif SAS4 PF15460.6 KPA43030.1 - 5.3e-29 100.2 1.6 5.3e-29 100.2 1.6 2.3 2 1 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 Peptidase_M1_N PF17900.1 KPA43031.1 - 6.2e-05 23.3 0.0 0.66 10.1 0.0 2.6 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KPA43031.1 - 0.0064 16.1 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Vps4_C PF09336.10 KPA43031.1 - 0.0098 15.9 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain HEAT_2 PF13646.6 KPA43031.1 - 0.033 14.6 0.0 0.52 10.7 0.0 2.9 3 0 0 3 3 3 0 HEAT repeats Rap1_C PF11626.8 KPA43032.1 - 4.4e-21 74.7 2.7 2e-20 72.6 0.1 2.5 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KPA43032.1 - 1.9e-14 53.6 0.9 4.4e-14 52.4 0.9 1.7 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 KPA43032.1 - 2.1e-09 37.7 0.0 5.2e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KPA43032.1 - 0.015 15.8 0.1 0.015 15.8 0.1 2.8 4 0 0 4 4 4 0 Rap1, DNA-binding Pkinase PF00069.25 KPA43033.1 - 2.2e-55 187.9 0.1 1.5e-35 122.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA43033.1 - 1.5e-37 129.3 0.0 3e-37 128.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA43033.1 - 0.00015 21.2 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KPA43033.1 - 0.17 11.8 3.2 0.18 11.7 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KPA43033.1 - 0.47 9.2 0.0 0.47 9.2 0.0 2.3 3 0 0 3 3 3 0 Fungal protein kinase DUF3896 PF13035.6 KPA43033.1 - 0.48 10.6 0.1 0.48 10.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Aminotran_1_2 PF00155.21 KPA43034.1 - 8.2e-37 127.2 0.0 9.7e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pirin PF02678.16 KPA43035.1 - 6.9e-30 103.2 0.0 1.6e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KPA43035.1 - 2.3e-25 88.9 0.0 1.6e-23 83.1 0.0 2.6 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KPA43035.1 - 1.4e-10 40.7 1.6 2.3e-06 27.2 0.4 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KPA43035.1 - 0.00033 20.3 0.2 0.38 10.5 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF861) VWA PF00092.28 KPA43036.1 - 1.2e-07 32.1 0.0 1.8e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KPA43036.1 - 0.0048 17.5 0.0 0.012 16.3 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KPA43036.1 - 0.006 16.7 0.0 0.011 15.8 0.0 1.5 1 1 0 1 1 1 1 vWA found in TerF C terminus BST2 PF16716.5 KPA43037.1 - 0.073 13.7 3.6 0.3 11.7 2.2 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 FlxA PF14282.6 KPA43037.1 - 0.087 12.8 0.2 0.087 12.8 0.2 3.1 3 1 1 4 4 4 0 FlxA-like protein XkdW PF09636.10 KPA43037.1 - 0.1 12.7 0.4 0.41 10.8 0.4 2.1 1 0 0 1 1 1 0 XkdW protein UPF0242 PF06785.11 KPA43037.1 - 0.19 11.8 8.9 0.084 13.0 6.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SKA2 PF16740.5 KPA43037.1 - 0.25 11.2 7.1 0.051 13.4 2.0 2.4 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Syntaxin-6_N PF09177.11 KPA43037.1 - 1.5 9.4 8.6 10 6.7 0.2 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal PAM2 PF07145.15 KPA43037.1 - 1.6 8.6 6.1 1 9.2 0.4 2.6 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DUF4094 PF13334.6 KPA43037.1 - 2.1 8.8 4.3 8.9 6.8 0.3 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) SOAR PF16533.5 KPA43037.1 - 2.3 8.2 6.7 0.49 10.4 2.1 2.1 1 1 2 3 3 3 0 STIM1 Orai1-activating region Spc7 PF08317.11 KPA43037.1 - 3 6.6 12.7 5.4 5.8 12.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KPA43037.1 - 3.1 7.9 12.5 3.7 7.6 1.9 3.3 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Syntaxin_2 PF14523.6 KPA43037.1 - 5.2 7.5 7.1 6 7.3 0.2 2.5 2 0 0 2 2 2 0 Syntaxin-like protein RRM_1 PF00076.22 KPA43038.1 - 6.8e-44 147.5 1.2 2.6e-20 72.0 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KPA43038.1 - 5.1e-24 85.2 0.3 1.6e-23 83.6 0.3 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KPA43038.1 - 0.00024 20.9 0.0 0.053 13.4 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KPA43038.1 - 0.0018 18.3 0.0 1.2 9.2 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KPA43038.1 - 0.0038 17.5 0.4 0.067 13.4 0.2 3.3 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KPA43038.1 - 0.0059 16.6 0.4 0.31 11.1 0.0 3.0 3 1 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KPA43038.1 - 0.0081 16.3 0.1 1.4 9.1 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 KPA43038.1 - 0.17 11.5 0.0 0.55 9.8 0.0 1.8 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.28 KPA43039.1 - 7.3e-18 64.5 0.2 7.3e-18 64.5 0.2 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KPA43039.1 - 1.8e-11 44.5 20.1 1.8e-11 44.5 20.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1453 PF07301.11 KPA43039.1 - 0.041 13.9 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) Anth_synt_I_N PF04715.13 KPA43039.1 - 0.093 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Het-C PF07217.11 KPA43040.1 - 3.3e-283 940.4 0.0 4.1e-283 940.1 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PP2C PF00481.21 KPA43041.1 - 2.3e-38 132.3 0.0 9e-33 114.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KPA43041.1 - 5.5e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C rRNA_methylase PF06962.12 KPA43042.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative rRNA methylase FTR1 PF03239.14 KPA43043.1 - 5.2e-77 259.0 7.4 6e-77 258.8 7.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family HTH_Tnp_Tc5 PF03221.16 KPA43043.1 - 0.17 11.9 0.6 0.33 11.0 0.1 1.6 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain DUF3119 PF11317.8 KPA43043.1 - 4.2 7.7 6.6 2.1 8.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3119) Cu-oxidase_3 PF07732.15 KPA43044.1 - 7e-46 155.1 2.8 1.8e-42 144.1 0.6 3.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KPA43044.1 - 6.5e-44 149.0 5.1 7.2e-39 132.7 0.2 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KPA43044.1 - 1.9e-39 135.3 1.3 2.2e-35 122.1 0.1 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KPA43044.1 - 0.0011 19.1 0.0 3.7 7.7 0.0 4.3 3 2 0 3 3 3 1 Cupredoxin-like domain DUF3450 PF11932.8 KPA43045.1 - 0.17 11.2 3.4 0.26 10.6 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fungal_trans PF04082.18 KPA43046.1 - 2.1e-09 36.8 0.0 3.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain OMPdecase PF00215.24 KPA43047.1 - 2.3e-108 361.0 0.0 2.8e-108 360.7 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family CDP-OH_P_transf PF01066.21 KPA43048.1 - 9.2e-13 48.8 0.3 9.2e-13 48.8 0.3 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SRP19 PF01922.17 KPA43049.1 - 2.8e-32 111.5 0.0 5.1e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Dynactin PF12455.8 KPA43050.1 - 6.9e-111 370.1 5.8 6.9e-111 370.1 5.8 4.3 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 KPA43050.1 - 4e-22 78.0 0.4 6.6e-22 77.3 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 KPA43050.1 - 0.0035 16.8 28.6 0.0035 16.8 28.6 4.9 3 2 1 5 5 5 1 Uncharacterized coiled-coil protein (DUF2353) ZapB PF06005.12 KPA43050.1 - 0.0048 17.3 5.0 0.0048 17.3 5.0 9.3 4 3 3 8 8 8 3 Cell division protein ZapB DUF2443 PF10398.9 KPA43050.1 - 4.4 7.4 7.4 1 9.4 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2443) HMG_box PF00505.19 KPA43051.1 - 1.6e-22 79.6 0.5 2.9e-22 78.8 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KPA43051.1 - 7.7e-07 29.6 0.3 1.6e-06 28.6 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain TIP49 PF06068.13 KPA43052.1 - 1.9e-167 556.9 0.1 2.3e-167 556.6 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KPA43052.1 - 6.2e-25 87.1 0.1 1.5e-24 85.9 0.1 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KPA43052.1 - 2.4e-11 44.2 1.0 4.3e-07 30.4 0.1 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPA43052.1 - 2.5e-09 37.1 0.0 1e-06 28.6 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KPA43052.1 - 0.00021 21.5 0.1 0.3 11.4 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KPA43052.1 - 0.00072 19.9 1.6 0.088 13.1 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KPA43052.1 - 0.00083 19.6 0.1 0.0022 18.3 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA43052.1 - 0.00097 19.6 0.1 0.0068 16.8 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KPA43052.1 - 0.0046 16.9 0.1 0.14 12.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KPA43052.1 - 0.0072 16.9 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KPA43052.1 - 0.016 14.5 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 KPA43052.1 - 0.022 14.5 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KPA43052.1 - 0.024 13.9 0.3 0.06 12.6 0.2 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KPA43052.1 - 0.027 14.0 0.1 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KPA43052.1 - 0.028 13.8 0.1 0.87 8.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KPA43052.1 - 0.032 14.0 0.1 0.065 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 KPA43052.1 - 0.062 12.5 0.2 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KPA43052.1 - 0.1 12.3 0.4 3.3 7.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain PhoLip_ATPase_C PF16212.5 KPA43053.1 - 1.1e-50 172.7 3.1 1.1e-50 172.7 3.1 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KPA43053.1 - 2.1e-16 59.4 0.3 4.1e-16 58.4 0.3 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KPA43053.1 - 6.3e-14 52.8 0.1 3.7e-07 30.7 0.0 3.6 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KPA43053.1 - 1.2e-07 31.5 0.2 0.00074 19.1 0.0 2.7 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 KPA43053.1 - 0.00015 21.8 0.0 0.004 17.2 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KPA43053.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Suc_Fer-like PF06999.12 KPA43054.1 - 1.3e-44 152.4 0.0 1.9e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FAD_binding_6 PF00970.24 KPA43054.1 - 9.6e-07 29.1 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KPA43054.1 - 0.00087 19.9 0.0 0.0078 16.9 0.0 2.4 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain Mitoc_mL59 PF18126.1 KPA43054.1 - 0.044 14.1 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 NAD_binding_6 PF08030.12 KPA43054.1 - 0.073 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Aa_trans PF01490.18 KPA43055.1 - 1e-84 284.6 31.5 1.3e-84 284.3 31.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.21 KPA43056.1 - 1.9e-49 168.6 31.5 2.4e-49 168.2 31.5 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KPA43056.1 - 9.1e-23 81.0 0.6 7.7e-10 38.4 0.0 3.2 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 KPA43056.1 - 1.5e-18 66.9 35.8 2.1e-18 66.4 35.8 1.2 1 0 0 1 1 1 1 Amino acid permease RecR PF02132.15 KPA43057.1 - 1.1 8.9 3.4 2 8.0 3.4 1.4 1 0 0 1 1 1 0 RecR protein cobW PF02492.19 KPA43058.1 - 8.4e-40 136.2 0.0 1.1e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KPA43058.1 - 6.4e-05 22.9 0.0 0.00039 20.3 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 KPA43058.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF463 PF04317.12 KPA43058.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_22 PF13401.6 KPA43058.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KPA43058.1 - 0.092 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 KPA43058.1 - 0.097 12.4 0.1 0.9 9.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 KPA43058.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.9 KPA43058.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 KPA43058.1 - 0.22 12.0 0.6 1.3 9.6 0.4 2.5 2 1 0 2 2 2 0 AAA domain PUL PF08324.11 KPA43059.1 - 2.2e-62 210.8 0.1 3e-62 210.4 0.1 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KPA43059.1 - 1.4e-23 83.4 0.0 2.4e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KPA43059.1 - 7.8e-15 54.7 0.0 1.4e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KPA43059.1 - 1.1e-06 28.6 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KPA43059.1 - 1.7e-05 25.2 0.3 5.8e-05 23.5 0.1 2.0 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KPA43059.1 - 0.0025 17.2 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KPA43059.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_3 PF13192.6 KPA43059.1 - 0.018 15.1 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain Redoxin PF08534.10 KPA43059.1 - 0.034 13.9 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 KPA43059.1 - 0.17 12.1 0.1 0.91 9.8 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin GDA1_CD39 PF01150.17 KPA43060.1 - 1.2e-103 347.0 0.0 1.6e-103 346.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AAA_lid_2 PF17863.1 KPA43061.1 - 1.3e-07 31.4 0.0 2.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain Ras PF00071.22 KPA43062.1 - 4.4e-56 189.0 0.0 5.1e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA43062.1 - 6.4e-32 110.3 0.0 9.2e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA43062.1 - 2.2e-13 50.0 0.0 2.5e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KPA43062.1 - 5.1e-08 33.0 0.0 8.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KPA43062.1 - 8.6e-07 28.5 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KPA43062.1 - 1.4e-05 24.7 0.0 0.00054 19.5 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPA43062.1 - 0.0002 21.3 0.2 0.0037 17.2 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase SRPRB PF09439.10 KPA43062.1 - 0.0031 17.0 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 KPA43062.1 - 0.0031 17.5 0.0 0.0084 16.1 0.0 1.7 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KPA43062.1 - 0.0039 16.9 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KPA43062.1 - 0.0056 16.5 0.2 0.19 11.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KPA43062.1 - 0.0064 16.9 0.0 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA43062.1 - 0.011 16.0 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KPA43062.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KPA43062.1 - 0.023 14.0 0.0 0.048 12.9 0.0 1.6 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 KPA43062.1 - 0.025 14.1 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 KPA43062.1 - 0.033 13.8 0.0 0.08 12.5 0.0 1.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KPA43062.1 - 0.074 12.9 0.3 0.13 12.2 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KPA43062.1 - 0.087 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KPA43062.1 - 0.1 11.8 0.1 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain TniB PF05621.11 KPA43062.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KPA43062.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.18 KPA43062.1 - 0.15 11.6 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.6 KPA43062.1 - 0.3 10.9 1.3 3.1 7.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Acyl-CoA_dh_1 PF00441.24 KPA43063.1 - 5.3e-28 98.1 0.3 9e-28 97.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPA43063.1 - 1.2e-20 73.5 0.0 2.1e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPA43063.1 - 3.5e-14 53.4 0.1 1.8e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KPA43063.1 - 2.2e-11 44.1 0.7 3.2e-11 43.6 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Spo12 PF05032.12 KPA43064.1 - 1.3e-16 60.2 1.1 3.4e-16 58.8 1.1 1.8 1 0 0 1 1 1 1 Spo12 family MMR_HSR1_Xtn PF16897.5 KPA43065.1 - 8.6e-35 119.0 3.3 1.1e-34 118.6 1.4 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KPA43065.1 - 5.3e-22 77.6 0.1 1.3e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.23 KPA43065.1 - 2.8e-21 75.7 0.2 6.7e-21 74.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPA43065.1 - 5.9e-13 48.6 0.0 9.4e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KPA43065.1 - 0.00042 20.4 3.5 0.038 14.0 0.0 2.7 2 1 1 3 3 3 2 Dynamin family MeaB PF03308.16 KPA43065.1 - 0.093 11.7 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 KPA43065.1 - 0.093 11.8 0.0 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain Torus PF16131.5 KPA43066.1 - 7.7e-44 148.9 0.3 1.7e-43 147.8 0.3 1.6 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 KPA43066.1 - 2.3e-08 33.8 0.0 5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KPA43066.1 - 0.0036 17.3 0.7 0.0066 16.5 0.7 1.5 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 KPA43066.1 - 0.009 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif UreF PF01730.16 KPA43067.1 - 7.1e-23 81.6 0.7 9.6e-23 81.2 0.7 1.2 1 0 0 1 1 1 1 UreF DUF429 PF04250.13 KPA43067.1 - 0.038 13.8 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF429) PRRSV_Env PF02340.15 KPA43067.1 - 0.056 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 PRRSV putative envelope protein Sugarporin_N PF11471.8 KPA43067.1 - 0.072 13.1 0.2 0.24 11.4 0.2 1.9 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Cut12 PF11500.8 KPA43068.1 - 8.2e-46 155.5 21.4 8.2e-46 155.5 21.4 3.7 2 1 0 2 2 2 1 Spindle pole body formation-associated protein Pox_A_type_inc PF04508.12 KPA43068.1 - 0.019 14.8 10.0 0.74 9.8 0.2 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat HGTP_anticodon2 PF12745.7 KPA43069.1 - 7.3e-84 281.4 2.8 7.3e-84 281.4 2.8 3.2 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 KPA43069.1 - 6.8e-73 245.3 3.7 8.5e-35 120.4 0.0 4.1 5 0 0 5 5 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KPA43069.1 - 4.4e-43 147.4 0.0 3e-19 69.3 0.0 3.7 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 KPA43069.1 - 1.6e-20 73.6 0.6 3.5e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 KPA43069.1 - 1.1e-12 48.3 0.5 3.3e-12 46.7 0.5 1.9 1 0 0 1 1 1 1 RWD domain APH PF01636.23 KPA43069.1 - 4.9e-05 23.4 3.3 0.058 13.3 0.0 3.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KPA43069.1 - 0.002 17.5 0.0 0.86 8.9 0.0 2.7 3 0 0 3 3 3 2 Kinase-like CENP-B_dimeris PF09026.10 KPA43069.1 - 0.078 13.4 8.0 0.25 11.8 8.0 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_ser-thr_kin PF05445.11 KPA43069.1 - 0.15 11.0 0.1 15 4.4 0.1 2.3 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Med21 PF11221.8 KPA43069.1 - 0.76 10.0 11.6 0.054 13.7 6.1 2.0 2 0 0 2 2 1 0 Subunit 21 of Mediator complex DUF1682 PF07946.14 KPA43069.1 - 1.7 7.8 14.5 3 7.0 14.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SUIM_assoc PF16619.5 KPA43069.1 - 2 8.5 6.0 6.1 7.0 6.0 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ALMT PF11744.8 KPA43069.1 - 4.2 6.1 6.0 9.8 4.9 6.0 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter UQ_con PF00179.26 KPA43070.1 - 1.3e-33 115.6 0.0 1.7e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KPA43070.1 - 0.0063 16.8 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.11 KPA43070.1 - 0.022 14.4 0.1 0.034 13.8 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 YL1 PF05764.13 KPA43070.1 - 8.4 6.4 9.3 12 5.9 9.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SAS4 PF15460.6 KPA43071.1 - 0.014 15.5 4.9 0.055 13.6 0.0 2.9 2 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF4245 PF14030.6 KPA43071.1 - 0.06 13.4 0.7 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) PSD4 PF07631.11 KPA43071.1 - 0.21 12.1 2.7 0.48 11.0 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) BRE1 PF08647.11 KPA43071.1 - 9.2 6.4 8.1 76 3.5 2.4 3.3 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DnaJ_C PF01556.18 KPA43072.1 - 3.4e-38 131.0 0.9 4.6e-38 130.6 0.9 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KPA43072.1 - 3.1e-26 91.3 3.0 5.1e-26 90.6 3.0 1.4 1 0 0 1 1 1 1 DnaJ domain HAD_2 PF13419.6 KPA43073.1 - 3.6e-24 85.8 0.0 4.6e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA43073.1 - 5.3e-10 39.9 0.1 1e-09 39.0 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 KPA43073.1 - 3.1e-07 30.3 0.0 0.0043 16.8 0.0 2.1 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase Hydrolase_like PF13242.6 KPA43073.1 - 7.3e-05 22.8 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like UDPG_MGDP_dh_C PF03720.15 KPA43073.1 - 0.017 15.5 0.0 0.18 12.3 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Rit1_C PF17184.4 KPA43074.1 - 3.3e-105 351.4 0.0 4.2e-105 351.1 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KPA43074.1 - 2e-37 127.9 0.0 3.7e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain GFO_IDH_MocA PF01408.22 KPA43075.1 - 1.8e-12 48.2 0.5 1.3e-11 45.4 0.5 2.3 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 KPA43075.1 - 0.0025 18.3 0.0 0.0059 17.1 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Sacchrp_dh_NADP PF03435.18 KPA43075.1 - 0.029 14.6 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 KPA43075.1 - 0.054 14.2 0.0 0.22 12.2 0.0 1.9 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain DHDPS PF00701.22 KPA43076.1 - 3.6e-31 108.0 0.0 4.3e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family YajC PF02699.15 KPA43076.1 - 0.078 12.9 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit MFS_1 PF07690.16 KPA43077.1 - 2.4e-46 158.3 39.9 2.4e-46 158.3 39.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA43077.1 - 4.9e-19 68.5 10.9 4.9e-19 68.5 10.9 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KPA43077.1 - 1.3e-07 30.5 10.8 1.3e-07 30.5 10.8 2.1 1 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) CRT-like PF08627.10 KPA43077.1 - 0.00093 18.2 2.4 0.0018 17.3 2.4 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like MARVEL PF01284.23 KPA43079.1 - 3.1e-05 24.0 9.2 5.9e-05 23.1 9.2 1.4 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.6 KPA43079.1 - 0.00065 20.1 0.3 0.0011 19.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) Nop16 PF09420.10 KPA43080.1 - 1.5e-66 224.4 9.2 1.7e-66 224.3 9.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 PYRIN PF02758.16 KPA43080.1 - 0.098 12.8 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain SlyX PF04102.12 KPA43081.1 - 2.4e-06 28.0 6.7 0.0013 19.3 0.2 2.3 2 0 0 2 2 2 2 SlyX Pox_A_type_inc PF04508.12 KPA43081.1 - 0.0021 17.8 2.2 0.0067 16.2 2.2 1.9 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat JAKMIP_CC3 PF16034.5 KPA43081.1 - 0.018 15.0 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 JAKMIP CC3 domain DivIC PF04977.15 KPA43081.1 - 0.13 12.0 6.1 0.38 10.6 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF2968 PF11180.8 KPA43081.1 - 4.8 6.8 9.8 9.4 5.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DAO PF01266.24 KPA43082.1 - 1.9e-65 221.7 0.5 2.2e-65 221.6 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA43082.1 - 9.6e-07 28.9 0.3 2.4e-06 27.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA43082.1 - 0.00068 19.0 0.1 0.0033 16.7 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPA43082.1 - 0.0032 16.9 1.1 0.0041 16.5 1.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA43082.1 - 0.0082 16.7 0.2 0.017 15.7 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA43082.1 - 0.017 14.4 0.2 0.048 12.9 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KPA43082.1 - 0.018 14.3 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KPA43082.1 - 0.032 13.5 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KPA43082.1 - 0.045 14.0 0.1 0.088 13.1 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 KPA43082.1 - 0.12 12.4 0.2 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KPA43082.1 - 0.13 11.3 0.7 0.23 10.5 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KPA43082.1 - 0.15 11.2 0.2 0.23 10.7 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA43082.1 - 0.24 10.4 0.2 0.38 9.7 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KPA43082.1 - 0.35 10.7 1.5 0.43 10.4 0.4 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2415 PF10313.9 KPA43083.1 - 8.4e-13 48.0 0.0 2.1e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 KPA43083.1 - 3.3e-05 24.1 0.0 0.061 13.6 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans PF04082.18 KPA43084.1 - 3.7e-34 118.0 0.0 6.3e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43084.1 - 5.7e-09 36.0 9.5 9.5e-09 35.3 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPA43085.1 - 2.3e-42 145.2 4.3 2.3e-42 145.2 4.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA43085.1 - 5.6e-10 38.7 1.2 5.6e-10 38.7 1.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Nuc_H_symport PF03825.16 KPA43085.1 - 0.0032 16.5 0.3 0.0032 16.5 0.3 1.6 2 0 0 2 2 2 1 Nucleoside H+ symporter MFS_1_like PF12832.7 KPA43085.1 - 0.2 10.5 16.6 0.018 13.9 3.3 2.5 2 1 0 2 2 2 0 MFS_1 like family ERCC3_RAD25_C PF16203.5 KPA43086.1 - 5.4e-121 402.5 0.2 8.8e-121 401.8 0.2 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KPA43086.1 - 8.5e-34 116.4 0.0 4.5e-33 114.1 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA43086.1 - 1.7e-15 57.4 0.0 3.1e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPA43086.1 - 2.6e-12 47.1 0.1 6.6e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KPA43086.1 - 2.4e-07 29.8 0.0 2.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rep_fac_C PF08542.11 KPA43086.1 - 0.098 13.1 0.0 0.51 10.8 0.0 2.1 2 0 0 2 2 2 0 Replication factor C C-terminal domain DUF473 PF04322.12 KPA43086.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF473) zf-CHY PF05495.12 KPA43087.1 - 2e-11 44.2 18.1 4.3e-11 43.1 18.1 1.5 1 0 0 1 1 1 1 CHY zinc finger RNA_POL_M_15KD PF02150.16 KPA43087.1 - 0.34 10.8 0.1 0.34 10.8 0.1 3.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit SIR2 PF02146.17 KPA43087.1 - 0.58 10.1 3.3 0.99 9.3 3.1 1.3 1 1 0 1 1 1 0 Sir2 family zf-DNL PF05180.12 KPA43087.1 - 0.93 9.5 8.2 5 7.1 4.6 2.6 2 1 0 2 2 2 0 DNL zinc finger Proteasome PF00227.26 KPA43088.1 - 1.4e-54 184.5 0.1 1.9e-54 184.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KPA43088.1 - 1.1e-11 44.1 0.4 3.2e-11 42.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAD-oxidase_C PF02913.19 KPA43090.1 - 6.4e-62 209.4 0.0 8.8e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KPA43090.1 - 3.3e-38 130.6 0.7 6e-38 129.7 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain CH PF00307.31 KPA43091.1 - 8.8e-48 161.0 0.2 7.1e-23 80.9 0.0 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KPA43091.1 - 5.5e-27 93.7 0.6 1.8e-24 85.6 0.1 2.9 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KPA43091.1 - 6.4e-12 45.1 0.1 1.7e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain Spectrin PF00435.21 KPA43091.1 - 5.9e-05 23.5 6.5 0.016 15.7 1.5 2.9 2 0 0 2 2 2 2 Spectrin repeat EF-hand_6 PF13405.6 KPA43091.1 - 0.00032 20.4 0.7 0.0032 17.3 0.1 2.9 3 0 0 3 3 2 1 EF-hand domain EF-hand_7 PF13499.6 KPA43091.1 - 0.0057 17.1 1.5 0.0057 17.1 1.5 2.4 2 0 0 2 2 2 1 EF-hand domain pair EIAV_Rev PF11129.8 KPA43091.1 - 0.02 15.1 3.1 0.043 14.0 1.4 2.2 2 0 0 2 2 2 0 Rev protein of equine infectious anaemia virus EF-hand_8 PF13833.6 KPA43091.1 - 0.022 14.6 0.5 0.46 10.4 0.1 3.0 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 KPA43091.1 - 0.041 13.4 0.3 0.79 9.4 0.0 2.6 2 0 0 2 2 2 0 EF hand zf-RRPl_C4 PF17026.5 KPA43091.1 - 0.076 13.1 0.2 0.26 11.4 0.1 1.9 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type RecG_N PF17190.4 KPA43091.1 - 2 9.2 4.3 7.2 7.4 0.0 3.5 4 0 0 4 4 3 0 RecG N-terminal helical domain PI3K_1B_p101 PF10486.9 KPA43091.1 - 4.1 5.1 12.9 6.8 4.3 12.9 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ribosomal_L19 PF01245.20 KPA43092.1 - 8.7e-11 41.7 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 PALP PF00291.25 KPA43094.1 - 4.3e-67 226.6 0.1 5.3e-67 226.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4 PF00097.25 KPA43095.1 - 8.8e-08 31.9 4.6 8.8e-08 31.9 4.6 5.9 6 2 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA43095.1 - 1.3e-06 28.3 4.3 1.3e-06 28.3 4.3 5.4 4 1 0 5 5 5 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KPA43095.1 - 1.8e-06 27.7 3.8 1.8e-06 27.7 3.8 5.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KPA43095.1 - 9e-06 25.5 0.6 9e-06 25.5 0.6 3.6 4 0 0 4 4 4 1 zf-RING of BARD1-type protein SH3_1 PF00018.28 KPA43095.1 - 1.1e-05 24.9 0.0 2.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain zf-RING_2 PF13639.6 KPA43095.1 - 1.5e-05 25.2 4.9 1.5e-05 25.2 4.9 5.1 4 2 2 6 6 6 1 Ring finger domain SH3_9 PF14604.6 KPA43095.1 - 1.7e-05 24.6 0.0 1.7e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain zf-RING_5 PF14634.6 KPA43095.1 - 5.6e-05 23.0 3.7 5.6e-05 23.0 3.7 5.8 5 1 1 6 6 6 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KPA43095.1 - 0.00029 20.9 3.6 0.00029 20.9 3.6 4.7 6 1 0 6 6 6 1 zinc finger of C3HC4-type, RING SH3_2 PF07653.17 KPA43095.1 - 0.0089 15.7 0.1 0.033 13.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain ECH_1 PF00378.20 KPA43096.1 - 2.7e-76 256.2 0.2 3.1e-76 256.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA43096.1 - 7.5e-35 121.0 0.4 4.7e-34 118.4 0.4 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KPA43096.1 - 0.076 13.0 0.0 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 Rer1 PF03248.13 KPA43097.1 - 8.9e-78 259.9 9.0 1e-77 259.7 9.0 1.0 1 0 0 1 1 1 1 Rer1 family Paf1 PF03985.13 KPA43098.1 - 3.8e-96 322.7 2.7 4.3e-96 322.5 2.7 1.0 1 0 0 1 1 1 1 Paf1 Glyco_transf_90 PF05686.12 KPA43099.1 - 8.2e-17 61.2 3.8 3.5e-15 55.8 3.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_S8 PF00410.19 KPA43100.1 - 7.5e-21 74.4 0.1 1e-20 73.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L7Ae PF01248.26 KPA43101.1 - 1.5e-28 98.3 0.5 1.9e-28 98.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.11 KPA43101.1 - 0.045 14.0 0.0 0.07 13.4 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family PELOTA_1 PF15608.6 KPA43101.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Rotamase_3 PF13616.6 KPA43102.1 - 1.7e-14 54.3 0.1 1.7e-14 54.3 0.1 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.21 KPA43102.1 - 1e-12 48.8 0.0 2.8e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 PPIC-type PPIASE domain SAD_SRA PF02182.17 KPA43102.1 - 1.2e-05 25.1 0.0 3e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 SAD/SRA domain TruD PF01142.18 KPA43103.1 - 3.4e-60 204.0 0.0 4.3e-56 190.5 0.0 3.4 3 0 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Pkinase PF00069.25 KPA43104.1 - 6.9e-63 212.5 0.0 8.3e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA43104.1 - 1.9e-34 119.1 0.0 2.7e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA43104.1 - 5.9e-06 25.8 0.0 9.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KPA43104.1 - 0.00065 18.6 0.0 0.00094 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KPA43104.1 - 0.14 11.7 0.0 6.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DEAD PF00270.29 KPA43105.1 - 6.4e-41 140.0 0.0 2.1e-40 138.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA43105.1 - 2.2e-31 108.5 0.1 1.1e-30 106.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA43105.1 - 1.6e-06 28.3 0.0 4.3e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KPA43105.1 - 0.025 13.3 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 KPA43105.1 - 0.027 14.2 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Cwf_Cwc_15 PF04889.12 KPA43105.1 - 0.22 11.2 9.4 0.38 10.5 9.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 KPA43105.1 - 0.62 10.5 7.9 1.8 9.0 7.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BUD22 PF09073.10 KPA43106.1 - 0.025 13.9 16.1 0.029 13.7 16.1 1.1 1 0 0 1 1 1 0 BUD22 Cag12 PF13117.6 KPA43106.1 - 0.34 11.5 2.1 0.54 10.8 0.1 2.2 2 0 0 2 2 2 0 Cag pathogenicity island protein Cag12 GCV_T PF01571.21 KPA43107.1 - 5.9e-05 22.6 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DUF2235 PF09994.9 KPA43108.1 - 1e-74 251.5 0.0 1.9e-74 250.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BppU_IgG PF18667.1 KPA43108.1 - 0.097 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain DnaJ PF00226.31 KPA43109.1 - 8.7e-14 51.4 0.0 8.7e-14 51.4 0.0 2.6 2 0 0 2 2 2 1 DnaJ domain DUF572 PF04502.13 KPA43109.1 - 1.1 8.8 17.3 1.8 8.1 17.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) BAF1_ABF1 PF04684.13 KPA43109.1 - 2.8 6.9 15.1 0.073 12.1 9.1 1.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor CDC45 PF02724.14 KPA43109.1 - 2.8 6.1 14.8 3.3 5.9 14.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Amidohydro_2 PF04909.14 KPA43110.1 - 1.8e-29 103.5 0.0 2.6e-29 102.9 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KPA43110.1 - 0.01 15.3 0.0 0.04 13.3 0.0 1.9 2 0 0 2 2 2 0 TatD related DNase DIOX_N PF14226.6 KPA43111.1 - 1.5e-25 90.2 0.0 2.4e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPA43111.1 - 8.8e-19 67.9 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PTPLA PF04387.14 KPA43112.1 - 1.6e-55 187.3 11.4 2.9e-55 186.5 11.4 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA PGAP1 PF07819.13 KPA43113.1 - 0.00059 19.6 0.0 0.00088 19.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KPA43113.1 - 0.0026 17.3 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KPA43113.1 - 0.0077 16.9 4.3 0.02 15.5 4.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA43113.1 - 0.017 14.4 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 KPA43113.1 - 0.26 10.8 0.0 0.65 9.5 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) SNF2_N PF00176.23 KPA43114.1 - 2.4e-73 246.9 0.4 2.4e-73 246.9 0.4 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA43114.1 - 1.3e-20 73.7 0.2 2.8e-18 66.3 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KPA43114.1 - 1.7e-20 72.9 0.1 4e-20 71.7 0.1 1.6 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 KPA43114.1 - 1.4e-18 67.0 14.9 1.4e-18 67.0 14.9 5.4 6 0 0 6 6 6 1 HSA SnAC PF14619.6 KPA43114.1 - 3.8e-16 59.5 0.9 3.8e-16 59.5 0.9 4.4 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KPA43114.1 - 6e-12 45.1 3.2 1.8e-11 43.6 3.2 1.9 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 KPA43114.1 - 4.5e-09 36.5 0.0 4.5e-09 36.5 0.0 3.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RBR PF17208.3 KPA43114.1 - 0.003 18.2 3.9 0.003 18.2 3.9 3.1 2 1 1 3 3 3 1 RNA binding Region WD40 PF00400.32 KPA43115.1 - 8e-08 32.8 20.7 0.006 17.4 0.6 5.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA43115.1 - 0.00018 21.7 0.1 0.92 9.8 0.1 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 KPA43115.1 - 0.15 12.0 0.0 0.72 9.8 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal RXT2_N PF08595.11 KPA43115.1 - 0.26 11.3 2.6 0.61 10.1 2.6 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KPA43115.1 - 1.8 7.8 5.8 3 7.1 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein BCNT PF07572.12 KPA43116.1 - 1.1e-21 76.6 0.6 3.1e-21 75.2 0.6 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development DUF4602 PF15375.6 KPA43116.1 - 2e-08 34.6 14.2 2e-08 34.6 14.2 3.6 2 2 0 2 2 2 1 Domain of unknown function (DUF4602) STE PF02200.16 KPA43117.1 - 4e-56 188.2 0.1 6.7e-56 187.4 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KPA43117.1 - 7.2e-11 41.9 12.8 4.3e-06 26.9 2.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPA43117.1 - 5.4e-08 32.9 4.8 5.4e-08 32.9 4.8 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPA43117.1 - 1.4e-07 31.7 10.2 0.00053 20.6 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA43117.1 - 0.0016 18.6 0.4 0.04 14.2 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KPA43117.1 - 0.0043 17.0 1.1 0.0043 17.0 1.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 KPA43117.1 - 0.071 13.4 0.3 0.18 12.1 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon zf-Di19 PF05605.12 KPA43117.1 - 0.1 12.9 3.5 0.19 12.0 3.5 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KPA43117.1 - 5.8 6.9 5.8 6.5 6.8 0.5 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF1899 PF08953.11 KPA43118.1 - 6.5e-34 115.6 0.1 1.2e-33 114.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KPA43118.1 - 1.1e-19 70.0 0.6 2.3e-19 69.0 0.6 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KPA43118.1 - 7.8e-17 61.4 2.7 9.4e-05 23.1 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA43118.1 - 1.6e-07 31.5 0.1 0.00083 19.6 0.0 3.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA43118.1 - 0.0018 17.0 0.7 0.24 10.0 0.1 2.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KPA43118.1 - 0.0073 15.3 0.0 0.9 8.4 0.0 2.3 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SDA1 PF05285.12 KPA43118.1 - 0.8 9.1 5.2 1.2 8.5 5.2 1.1 1 0 0 1 1 1 0 SDA1 Anillin PF08174.11 KPA43119.1 - 1.1e-11 45.3 0.0 3.5e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KPA43119.1 - 1.4e-07 31.9 0.0 5.4e-07 30.1 0.0 2.1 1 0 0 1 1 1 1 PH domain His_biosynth PF00977.21 KPA43120.1 - 3.3e-36 124.9 0.0 3.9e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KPA43120.1 - 0.033 13.6 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Lactamase_B_2 PF12706.7 KPA43121.1 - 5.6e-14 52.1 0.1 1.2e-13 51.1 0.1 1.5 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KPA43121.1 - 1.9e-12 47.4 0.6 1.1e-11 45.0 0.6 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KPA43121.1 - 0.047 13.7 2.7 0.81 9.7 1.2 2.6 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily ERG2_Sigma1R PF04622.12 KPA43122.1 - 2.5e-98 327.5 0.0 3e-98 327.3 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein UCR_6-4kD PF08997.10 KPA43122.1 - 0.086 12.8 0.1 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein NPCC PF08058.11 KPA43124.1 - 4.2e-27 94.8 0.0 5.8e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component ADH_N PF08240.12 KPA43125.1 - 9.1e-20 70.6 0.1 2.1e-19 69.4 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA43125.1 - 2.7e-15 56.5 0.0 5.1e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPA43125.1 - 0.031 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 KPA43125.1 - 0.092 13.2 0.0 0.24 11.9 0.0 1.7 2 0 0 2 2 2 0 CoA binding domain FAA_hydrolase PF01557.18 KPA43126.1 - 8e-55 185.9 0.0 1e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF410 PF04190.13 KPA43127.1 - 2e-93 312.9 0.0 2.6e-93 312.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) UPF0220 PF05255.11 KPA43128.1 - 4.3e-66 221.5 2.9 4.9e-66 221.4 2.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Zip PF02535.22 KPA43129.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 KPA43129.1 - 3.6 6.3 7.8 5.2 5.8 7.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KPA43129.1 - 5.7 5.6 9.7 7.9 5.1 9.7 1.1 1 0 0 1 1 1 0 Presenilin Sec2p PF06428.11 KPA43130.1 - 3.2e-12 46.3 13.0 3.2e-12 46.3 13.0 3.2 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p Spore_III_AF PF09581.10 KPA43130.1 - 1.3 9.0 12.0 2.1 8.3 12.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF4140 PF13600.6 KPA43130.1 - 3.5 8.1 24.2 7.1 7.1 5.2 3.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) HAUS-augmin3 PF14932.6 KPA43130.1 - 3.8 7.0 20.7 10 5.6 16.8 2.9 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 EXOSC1 PF10447.9 KPA43131.1 - 1.1e-18 67.9 4.3 5.9e-14 52.6 0.2 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KPA43131.1 - 3.2e-11 42.8 0.7 6.9e-11 41.8 0.7 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region PCB_OB PF17092.5 KPA43131.1 - 0.021 15.6 1.0 0.035 14.9 0.9 1.5 1 1 0 1 1 1 0 Penicillin-binding protein OB-like domain ABC_membrane PF00664.23 KPA43132.1 - 1e-49 169.6 38.0 3.6e-34 118.7 22.9 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA43132.1 - 2.9e-48 163.8 0.0 7.5e-27 94.5 0.0 2.9 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KPA43132.1 - 1.8e-06 28.0 1.0 0.042 13.9 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KPA43132.1 - 1.4e-05 25.5 0.1 0.089 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KPA43132.1 - 2.3e-05 24.4 2.3 0.0062 16.5 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KPA43132.1 - 2.8e-05 23.8 1.3 0.046 13.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KPA43132.1 - 6.4e-05 22.3 0.0 0.0046 16.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 KPA43132.1 - 7.4e-05 22.7 0.1 0.38 10.5 0.1 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPA43132.1 - 0.00094 18.7 1.8 1.9 7.9 0.0 3.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KPA43132.1 - 0.0012 19.0 2.2 0.3 11.2 1.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain MeaB PF03308.16 KPA43132.1 - 0.0017 17.4 1.0 0.79 8.7 0.5 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 KPA43132.1 - 0.0091 15.7 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Roc PF08477.13 KPA43132.1 - 0.014 15.6 0.4 2 8.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KPA43132.1 - 0.015 14.8 0.6 2.3 7.7 0.2 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KPA43132.1 - 0.016 15.4 0.8 13 6.1 0.2 3.2 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KPA43132.1 - 0.018 14.7 2.3 2.5 7.8 0.2 2.7 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KPA43132.1 - 0.032 13.6 0.0 9.9 5.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ploopntkinase3 PF18751.1 KPA43132.1 - 0.046 13.6 0.1 17 5.2 0.0 2.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KPA43132.1 - 0.061 13.7 0.3 7.3 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.7 KPA43132.1 - 0.081 11.8 1.8 1.3 7.9 0.4 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.6 KPA43132.1 - 0.12 12.0 1.0 3.8 7.1 0.1 2.9 3 0 0 3 3 3 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KPA43132.1 - 0.2 10.5 3.1 7.8 5.3 0.0 2.7 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Orf78 PF06024.12 KPA43132.1 - 1 9.7 6.9 0.94 9.8 0.9 3.4 4 0 0 4 4 2 0 Orf78 (ac78) AAA_23 PF13476.6 KPA43132.1 - 1.2 9.6 0.0 1.2 9.6 0.0 4.3 5 0 0 5 5 4 0 AAA domain Dynamin_N PF00350.23 KPA43132.1 - 3.3 7.7 15.1 0.066 13.3 0.6 3.7 4 0 0 4 4 3 0 Dynamin family TruB_N PF01509.18 KPA43133.1 - 1.5e-45 155.2 0.3 5.6e-45 153.4 0.0 1.9 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KPA43133.1 - 9.9e-06 25.6 0.0 1.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DNMT1-RFD PF12047.8 KPA43134.1 - 8.7e-05 22.6 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain MIF4G_like PF09088.11 KPA43135.1 - 1.9e-85 285.5 0.1 3e-85 284.8 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KPA43135.1 - 6.1e-68 229.2 0.0 1.2e-67 228.3 0.0 1.5 2 0 0 2 2 2 1 MIF4G like Pkinase PF00069.25 KPA43136.1 - 1.6e-64 217.8 0.0 1.9e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA43136.1 - 5.6e-25 88.1 0.0 7.3e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA43136.1 - 4e-06 26.3 0.0 2.2e-05 23.9 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 KPA43136.1 - 0.0027 17.7 0.2 0.011 15.6 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1229 PF06797.11 KPA43136.1 - 0.006 16.8 0.2 0.0095 16.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) Kdo PF06293.14 KPA43136.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KPA43136.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KPA43136.1 - 0.18 10.8 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 6PF2K PF01591.18 KPA43137.1 - 5.6e-59 199.1 0.0 8.3e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KPA43137.1 - 1.3e-20 73.9 0.4 5.2e-20 72.0 0.4 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KPA43137.1 - 0.0093 16.1 0.0 0.062 13.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain ZnuA PF01297.17 KPA43137.1 - 0.12 11.8 0.1 0.39 10.1 0.0 1.9 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic IstB_IS21 PF01695.17 KPA43137.1 - 0.18 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Porin_3 PF01459.22 KPA43138.1 - 1.3e-83 280.6 0.0 1.5e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin UCH_1 PF13423.6 KPA43139.1 - 2.3e-42 145.8 0.0 1.4e-41 143.1 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KPA43139.1 - 4.3e-18 65.7 0.0 8.4e-18 64.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SelP_N PF04592.14 KPA43139.1 - 4.9 6.5 9.7 11 5.4 9.7 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CN_hydrolase PF00795.22 KPA43140.1 - 6.5e-50 169.9 0.0 8.7e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TAF4 PF05236.14 KPA43141.1 - 1e-29 104.2 2.2 8.1e-25 88.1 0.6 2.1 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family ColG_sub PF18496.1 KPA43141.1 - 0.024 14.8 0.2 0.045 13.9 0.2 1.4 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain CPSF73-100_C PF11718.8 KPA43142.1 - 3.2e-88 294.9 0.1 4.5e-88 294.4 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KPA43142.1 - 1.3e-29 102.7 0.0 3e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KPA43142.1 - 1.9e-18 67.2 0.6 3.4e-18 66.3 0.6 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KPA43142.1 - 2.2e-18 66.4 0.1 4.2e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KPA43142.1 - 3.1e-12 46.2 0.0 6.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 KPA43142.1 - 5.6e-06 26.3 0.1 1.5e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KPA43142.1 - 8.7e-06 25.4 1.2 1.7e-05 24.4 0.6 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain V_ATPase_I PF01496.19 KPA43143.1 - 0 1033.2 0.0 0 1033.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KPA43143.1 - 0.029 14.4 2.4 1.8 8.6 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3552 PF12072.8 KPA43143.1 - 0.054 12.9 4.4 2.8 7.3 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF842 PF05811.13 KPA43143.1 - 0.063 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Baculo_PEP_C PF04513.12 KPA43143.1 - 0.087 12.9 5.6 1 9.4 2.3 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.12 KPA43143.1 - 0.11 10.7 6.8 0.39 8.8 0.6 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA CheZ PF04344.13 KPA43143.1 - 0.11 12.4 2.2 2 8.3 0.1 2.7 3 0 0 3 3 3 0 Chemotaxis phosphatase, CheZ YojJ PF10372.9 KPA43143.1 - 0.11 12.6 0.1 29 4.9 0.1 3.3 3 0 0 3 3 2 0 Bacterial membrane-spanning protein N-terminus SprT-like PF10263.9 KPA43143.1 - 0.14 12.1 0.2 1.2 9.0 0.3 2.4 2 0 0 2 2 2 0 SprT-like family SKA2 PF16740.5 KPA43143.1 - 0.23 11.2 4.5 11 5.9 0.2 2.9 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Phage_GP20 PF06810.11 KPA43143.1 - 0.28 11.0 2.5 15 5.4 0.4 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 CLZ PF16526.5 KPA43143.1 - 0.32 11.4 4.9 6.1 7.3 0.2 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Golgin_A5 PF09787.9 KPA43143.1 - 0.37 10.2 6.6 0.33 10.4 0.9 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 KPA43143.1 - 0.6 8.9 5.0 6.2 5.6 0.7 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF16 PF01519.16 KPA43143.1 - 0.76 10.3 4.1 16 6.0 0.7 3.3 3 1 0 3 3 3 0 Protein of unknown function DUF16 SesA PF17107.5 KPA43143.1 - 0.89 9.8 2.8 2.3 8.4 0.3 2.7 2 1 1 3 3 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases UPF0449 PF15136.6 KPA43143.1 - 1.1 9.7 3.7 13 6.3 0.5 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Filament PF00038.21 KPA43143.1 - 1.5 8.3 6.9 6.5 6.2 1.1 2.4 2 0 0 2 2 2 0 Intermediate filament protein Snapin_Pallidin PF14712.6 KPA43143.1 - 3.1 8.3 5.6 15 6.1 0.4 3.0 2 1 0 2 2 2 0 Snapin/Pallidin Prefoldin_2 PF01920.20 KPA43143.1 - 3.2 7.8 5.7 25 4.9 0.3 2.7 3 0 0 3 3 2 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 KPA43143.1 - 3.4 7.7 5.6 1.6 8.7 1.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.13 KPA43143.1 - 5.4 7.1 7.2 31 4.6 2.0 2.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HMMR_N PF15905.5 KPA43143.1 - 5.4 6.4 5.6 15 5.0 1.0 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal BLOC1_2 PF10046.9 KPA43143.1 - 6.8 7.1 8.3 5.4 7.4 0.9 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 cNMP_binding PF00027.29 KPA43144.1 - 3.6e-32 110.3 0.0 1.9e-19 69.5 0.0 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Bax1-I PF01027.20 KPA43144.1 - 4.2e-32 111.7 8.9 7e-32 110.9 8.9 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 cNMPbd_u2 PF16643.5 KPA43144.1 - 5.2e-31 108.2 11.5 1.4e-30 106.8 11.5 1.7 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein F-box PF00646.33 KPA43144.1 - 3.2e-08 33.2 0.3 3.2e-08 33.2 0.3 2.2 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 KPA43144.1 - 8.7e-08 31.6 3.3 0.063 13.4 0.0 5.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KPA43144.1 - 3.2e-05 24.2 0.0 0.093 13.2 0.0 4.0 3 1 2 5 5 5 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KPA43144.1 - 4.2e-05 23.4 0.7 0.00018 21.4 0.1 2.3 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 KPA43144.1 - 0.0029 17.9 3.4 18 6.4 0.0 5.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_8 PF13855.6 KPA43144.1 - 0.097 12.4 0.0 3.1 7.6 0.0 2.9 2 0 0 2 2 2 0 Leucine rich repeat PMSR PF01625.21 KPA43145.1 - 1e-60 204.4 0.4 1.2e-60 204.1 0.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Amidohydro_2 PF04909.14 KPA43146.1 - 1.9e-31 109.9 0.1 2.2e-31 109.8 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.18 KPA43147.1 - 2.3e-22 79.3 1.5 3.6e-22 78.7 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43147.1 - 1.6e-09 37.7 7.8 3.1e-09 36.8 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PKcGMP_CC PF16808.5 KPA43147.1 - 0.38 10.7 1.4 0.85 9.5 1.4 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MIP PF00230.20 KPA43149.1 - 5.8e-44 150.5 15.1 7.2e-44 150.2 15.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein 2-Hacid_dh_C PF02826.19 KPA43150.1 - 1.2e-48 164.8 0.1 8.1e-48 162.1 0.1 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPA43150.1 - 7e-08 32.2 0.0 3.3e-07 30.0 0.0 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KPA43150.1 - 0.023 14.9 0.1 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase SAP PF02037.27 KPA43150.1 - 0.1 12.4 1.5 4.2 7.2 0.0 3.5 3 1 0 3 3 3 0 SAP domain adh_short PF00106.25 KPA43151.1 - 1.2e-33 116.3 0.2 1.5e-33 115.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA43151.1 - 8.3e-30 104.1 0.1 1e-29 103.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA43151.1 - 4.5e-10 39.7 0.5 9.4e-10 38.7 0.5 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KPA43151.1 - 0.036 13.1 0.1 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPA43151.1 - 0.051 13.0 0.0 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ras PF00071.22 KPA43152.1 - 9.5e-43 145.6 0.0 1.3e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA43152.1 - 5.2e-31 107.4 0.0 9.4e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA43152.1 - 9.1e-12 44.8 0.0 1e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KPA43152.1 - 1.4e-07 31.6 0.0 5.3e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase PduV-EutP PF10662.9 KPA43152.1 - 0.0012 18.6 0.0 0.67 9.7 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KPA43152.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 KPA43152.1 - 0.009 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 KPA43152.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KPA43152.1 - 0.017 15.0 0.4 0.13 12.1 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase AAA_28 PF13521.6 KPA43152.1 - 0.025 14.8 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KPA43152.1 - 0.037 14.3 0.1 0.12 12.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KPA43152.1 - 0.038 14.5 0.2 0.14 12.7 0.2 2.0 1 1 1 2 2 2 0 ABC transporter AAA_16 PF13191.6 KPA43152.1 - 0.058 13.8 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KPA43152.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KPA43152.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Mannosidase_ig PF17786.1 KPA43153.1 - 1.3e-12 48.2 0.8 3e-12 47.0 0.2 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KPA43153.1 - 3.6e-11 43.7 5.5 5.8e-11 43.0 0.1 2.8 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KPA43153.1 - 2.4e-06 27.6 0.0 6.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 KPA43153.1 - 1.6e-05 24.6 0.0 4.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 KPA43153.1 - 0.00092 18.4 0.3 0.0026 16.9 0.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Peptidase_S8 PF00082.22 KPA43154.1 - 1.7e-30 106.4 22.6 3.3e-30 105.4 22.5 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KPA43154.1 - 1.9e-17 63.7 0.1 4.9e-17 62.4 0.1 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Malic_M PF03949.15 KPA43155.1 - 8.6e-89 297.2 0.0 1.1e-88 296.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KPA43155.1 - 8.3e-69 231.0 0.1 2.3e-68 229.6 0.0 1.8 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain DUF5427 PF10310.9 KPA43156.1 - 1e-175 585.2 0.1 1.2e-175 585.0 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Ribosomal_L14 PF00238.19 KPA43158.1 - 1.2e-32 112.5 0.0 1.4e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e NUDIX PF00293.28 KPA43159.1 - 4.1e-07 30.1 0.0 9.7e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain Fungal_trans PF04082.18 KPA43160.1 - 5.8e-20 71.4 0.0 9.9e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43160.1 - 1.8e-09 37.6 11.0 3.1e-09 36.8 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Slx4 PF09494.10 KPA43161.1 - 8.1e-21 73.7 0.0 2.2e-20 72.4 0.0 1.7 2 0 0 2 2 2 1 Slx4 endonuclease Ribosomal_S21e PF01249.18 KPA43162.1 - 1.8e-41 140.1 0.1 2e-41 139.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FAD_binding_7 PF03441.14 KPA43163.1 - 2.5e-82 275.3 0.6 7.5e-82 273.7 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KPA43163.1 - 1e-39 136.2 0.0 1.6e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 KPA43163.1 - 0.022 15.3 0.1 0.053 14.0 0.1 1.7 1 0 0 1 1 1 0 Universal stress protein family XLF PF09302.11 KPA43164.1 - 7.3e-56 189.2 0.0 1.5e-55 188.2 0.0 1.5 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Forkhead PF00250.18 KPA43165.1 - 6e-17 61.7 2.2 1.6e-16 60.3 0.9 2.3 2 1 0 2 2 2 1 Forkhead domain MAP65_ASE1 PF03999.12 KPA43165.1 - 9 4.9 8.2 0.27 9.9 1.4 1.7 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Cactin_mid PF10312.9 KPA43166.1 - 9.7e-64 214.8 6.9 1.5e-63 214.2 6.9 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KPA43166.1 - 6.7e-51 171.5 2.5 1.3e-50 170.5 2.5 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Pox_VLTF3 PF04947.14 KPA43166.1 - 0.0052 16.5 2.3 0.0068 16.1 0.5 1.9 2 0 0 2 2 2 1 Poxvirus Late Transcription Factor VLTF3 like SF3A2 PF16835.5 KPA43166.1 - 0.0074 16.6 0.0 0.026 14.9 0.0 1.9 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF1525 PF07511.11 KPA43166.1 - 0.024 14.8 0.8 0.064 13.4 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) DUF1087 PF06465.13 KPA43166.1 - 0.043 13.8 0.7 0.043 13.8 0.7 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Pkinase PF00069.25 KPA43168.1 - 1.4e-34 119.7 0.0 2.4e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA43168.1 - 8.7e-17 61.2 0.0 1.1e-15 57.6 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 KPA43168.1 - 0.00019 21.6 0.0 0.00038 20.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Kinase-like PF14531.6 KPA43168.1 - 0.00044 19.7 0.0 0.0011 18.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KPA43168.1 - 0.039 13.9 0.0 0.086 12.7 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family IBN_N PF03810.19 KPA43169.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Importin-beta N-terminal domain Peptidase_S9 PF00326.21 KPA43170.1 - 3.7e-39 134.4 0.0 5.6e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KPA43170.1 - 3.4e-08 33.0 4.2 0.0018 17.6 1.7 2.6 1 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 KPA43170.1 - 2.3e-07 30.6 0.1 8.4e-07 28.8 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KPA43170.1 - 2.7e-05 23.9 0.1 0.16 11.5 0.7 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 KPA43170.1 - 3.6e-05 23.8 0.0 7.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein PD40 PF07676.12 KPA43170.1 - 0.0001 22.1 0.8 0.0039 17.1 0.1 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.13 KPA43170.1 - 0.0048 16.8 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KPA43170.1 - 0.0098 15.6 0.0 0.16 11.6 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_M14 PF00246.24 KPA43170.1 - 0.026 14.3 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Zinc carboxypeptidase Amino_oxidase PF01593.24 KPA43171.1 - 2.6e-17 63.3 0.0 4.5e-16 59.2 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA43171.1 - 6.9e-08 32.6 0.0 1.8e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA43171.1 - 2.4e-05 24.1 0.0 5e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KPA43171.1 - 0.00015 21.1 0.3 0.00027 20.3 0.3 1.4 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KPA43171.1 - 0.00047 19.4 0.3 0.0007 18.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPA43171.1 - 0.00055 19.3 0.1 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA43171.1 - 0.00099 18.4 0.0 0.0027 17.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA43171.1 - 0.0011 17.8 0.1 0.03 13.0 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KPA43171.1 - 0.0013 18.2 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPA43171.1 - 0.0038 16.5 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KPA43171.1 - 0.011 16.2 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA43171.1 - 0.076 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Aldolase_II PF00596.21 KPA43172.1 - 1.9e-48 164.9 0.1 2.7e-48 164.4 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1275 PF06912.11 KPA43174.1 - 4.3e-44 150.8 14.5 5e-44 150.5 14.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1435 PF07256.12 KPA43174.1 - 0.18 11.9 2.9 0.69 10.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1435) MFS_1 PF07690.16 KPA43175.1 - 3.1e-31 108.6 31.3 3.1e-31 108.6 31.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily HD_3 PF13023.6 KPA43175.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 HD domain Tetraspanin PF00335.20 KPA43175.1 - 0.89 9.2 5.4 2.4 7.8 1.4 3.1 2 1 1 3 3 3 0 Tetraspanin family Pkinase PF00069.25 KPA43176.1 - 9e-75 251.4 0.0 1.3e-74 250.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA43176.1 - 6.1e-38 130.6 0.0 1.3e-37 129.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA43176.1 - 0.00036 20.0 1.2 0.58 9.4 0.1 2.8 2 1 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KPA43176.1 - 0.018 13.8 0.0 0.018 13.8 0.0 2.1 2 1 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KPA43176.1 - 0.028 14.4 0.0 0.13 12.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cutinase PF01083.22 KPA43178.1 - 1.9e-39 135.5 0.0 2.5e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KPA43178.1 - 0.0015 18.4 0.0 0.004 17.1 0.0 1.6 1 1 1 2 2 2 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KPA43178.1 - 0.0028 17.2 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain JAB PF01398.21 KPA43180.1 - 3.7e-33 114.0 0.0 6.4e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KPA43180.1 - 4.6e-12 46.4 0.4 1e-11 45.2 0.4 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KPA43180.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.19 KPA43181.1 - 5.6e-82 275.7 0.1 9.8e-82 274.9 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain RNA_pol_Rpc34 PF05158.12 KPA43182.1 - 8e-100 334.5 0.0 9.9e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 KPA43182.1 - 0.00076 20.1 0.1 0.019 15.6 0.0 2.7 3 0 0 3 3 3 1 Replication protein A C terminal B-block_TFIIIC PF04182.12 KPA43182.1 - 0.014 15.5 0.1 0.045 13.9 0.0 1.9 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC HTH_36 PF13730.6 KPA43182.1 - 0.026 14.5 0.0 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Rrf2 PF02082.20 KPA43182.1 - 0.026 14.8 0.1 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator Ribosomal_S25 PF03297.15 KPA43182.1 - 0.043 14.0 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 S25 ribosomal protein MarR PF01047.22 KPA43182.1 - 0.1 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 MarR family Mnd1 PF03962.15 KPA43182.1 - 0.22 11.8 0.8 6.5 7.1 0.1 2.8 3 0 0 3 3 3 0 Mnd1 HTH domain Pro_isomerase PF00160.21 KPA43183.1 - 2.1e-43 148.4 0.5 2.6e-43 148.0 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 KPA43184.1 - 3.7e-45 153.0 0.1 5.5e-45 152.4 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KPA43184.1 - 0.0028 16.7 0.0 0.0037 16.3 0.0 1.1 1 0 0 1 1 1 1 ANTH domain MARVEL PF01284.23 KPA43185.1 - 9.6e-06 25.7 9.2 1.6e-05 25.0 9.2 1.3 1 1 0 1 1 1 1 Membrane-associating domain Fungal_trans_2 PF11951.8 KPA43187.1 - 1.4e-66 224.9 0.4 2.4e-66 224.1 0.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43187.1 - 2.5e-08 33.9 7.1 5.1e-08 32.9 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA43187.1 - 0.083 11.9 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ctr PF04145.15 KPA43188.1 - 1.1e-39 136.4 0.8 1.3e-39 136.2 0.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family YfhO PF09586.10 KPA43188.1 - 0.4 8.9 6.5 0.48 8.6 5.8 1.4 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Nic96 PF04097.14 KPA43189.1 - 1.8e-221 736.9 0.0 2.4e-221 736.5 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KPA43189.1 - 2.3e-14 54.0 106.6 3e-09 37.6 47.2 4.7 2 1 2 4 4 4 3 Nucleoporin FG repeat region FGGY_C PF02782.16 KPA43190.1 - 3.6e-49 167.2 0.2 5.2e-49 166.7 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KPA43190.1 - 1.1e-25 90.6 0.4 2.5e-22 79.6 0.0 2.8 3 1 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KPA43190.1 - 0.064 12.7 0.3 0.75 9.2 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family VTC PF09359.10 KPA43192.1 - 1.1e-88 297.3 1.4 1.1e-88 297.3 1.4 1.5 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KPA43192.1 - 1.2e-11 44.9 4.4 2.6e-11 43.8 4.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KPA43192.1 - 1.8e-07 31.4 5.9 9e-05 22.5 0.2 4.2 3 1 2 5 5 5 2 SPX domain MgtE PF01769.16 KPA43192.1 - 0.057 13.8 0.1 0.089 13.2 0.1 1.3 1 0 0 1 1 1 0 Divalent cation transporter GATase_2 PF00310.21 KPA43193.1 - 3.9e-183 608.9 0.0 5.3e-183 608.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KPA43193.1 - 5.8e-155 516.0 0.0 5.2e-154 512.8 0.0 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KPA43193.1 - 1.6e-111 372.3 0.0 7.8e-111 370.0 0.0 1.9 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KPA43193.1 - 5.5e-86 287.0 3.5 8.8e-86 286.4 3.5 1.3 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 KPA43193.1 - 2.7e-21 75.5 0.1 5.7e-21 74.4 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 KPA43193.1 - 3.5e-20 72.4 0.1 3.4e-19 69.2 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA43193.1 - 8.5e-08 32.3 0.1 3e-07 30.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPA43193.1 - 1.4e-07 31.9 0.0 0.0011 19.5 0.1 3.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPA43193.1 - 9.2e-06 25.2 0.2 1.9e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KPA43193.1 - 9.5e-06 25.4 3.9 0.0023 17.6 0.6 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA43193.1 - 1.4e-05 24.6 0.9 0.19 10.9 0.1 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPA43193.1 - 7e-05 22.4 0.1 0.00013 21.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA43193.1 - 0.00014 20.7 0.2 0.00035 19.4 0.2 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KPA43193.1 - 0.00081 18.6 0.1 0.0019 17.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KPA43193.1 - 0.0017 17.7 0.0 0.0037 16.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KPA43193.1 - 0.0029 18.0 1.7 3.3 8.2 0.1 3.0 3 0 0 3 3 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KPA43193.1 - 0.0048 16.2 0.1 0.73 9.1 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KPA43193.1 - 0.021 14.1 0.2 0.058 12.6 0.2 1.7 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KPA43193.1 - 0.033 13.3 0.2 1.4 7.9 0.1 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein GATase_6 PF13522.6 KPA43193.1 - 0.04 14.1 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 Glutamine amidotransferase domain FMN_dh PF01070.18 KPA43193.1 - 0.12 11.4 0.8 1 8.3 1.0 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase 2-Hacid_dh_C PF02826.19 KPA43193.1 - 0.14 11.5 0.1 0.8 9.0 0.0 2.2 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.19 KPA43193.1 - 0.19 10.1 0.1 4.1 5.7 0.0 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like GIDA PF01134.22 KPA43193.1 - 0.34 9.9 2.5 0.27 10.2 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Apc15p PF05841.11 KPA43194.1 - 1.4e-20 74.4 1.5 1.4e-20 74.4 1.5 2.9 2 1 1 3 3 3 2 Apc15p protein Use1 PF09753.9 KPA43195.1 - 3.6e-05 23.6 0.0 3.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 CHZ PF09649.10 KPA43196.1 - 6.9e-17 60.6 0.9 6.9e-17 60.6 0.9 2.1 2 1 0 2 2 2 1 Histone chaperone domain CHZ UPF0370 PF13980.6 KPA43197.1 - 0.15 12.2 0.3 0.22 11.6 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) P68HR PF08061.11 KPA43197.1 - 0.23 11.6 0.5 2.1 8.5 0.1 2.1 2 0 0 2 2 2 0 P68HR (NUC004) repeat Cyclin PF08613.11 KPA43198.1 - 4.5e-31 108.4 0.0 9.6e-31 107.3 0.0 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KPA43198.1 - 9.8e-05 22.1 0.1 0.00016 21.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SOG2 PF10428.9 KPA43198.1 - 0.032 13.5 13.4 0.041 13.1 13.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 KPA43198.1 - 3.6 6.2 5.1 4.4 5.9 5.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 KPA43198.1 - 6.2 6.6 13.0 8.2 6.2 13.0 1.2 1 0 0 1 1 1 0 SPX domain Arm PF00514.23 KPA43199.1 - 6.1e-09 35.6 15.5 0.00043 20.2 0.2 7.8 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KPA43199.1 - 0.0016 18.9 14.8 0.13 12.8 0.1 7.3 6 1 1 7 7 7 1 HEAT-like repeat V-ATPase_H_C PF11698.8 KPA43199.1 - 0.0042 17.2 0.5 1.6 8.9 0.0 2.9 2 0 0 2 2 2 2 V-ATPase subunit H HEAT PF02985.22 KPA43199.1 - 0.0074 16.5 15.1 8.8 6.9 0.0 7.6 8 0 0 8 8 8 2 HEAT repeat Bac_rhodopsin PF01036.18 KPA43200.1 - 2.6e-30 105.7 25.5 3.3e-30 105.3 25.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Spore_III_AE PF09546.10 KPA43200.1 - 0.17 11.1 5.8 2.8 7.1 1.7 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AE (spore_III_AE) DUF4064 PF13273.6 KPA43200.1 - 0.28 11.5 0.0 0.28 11.5 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Velvet PF11754.8 KPA43201.1 - 6.8e-51 173.6 10.7 2.7e-33 116.0 0.0 3.4 2 2 1 3 3 3 2 Velvet factor Ank_5 PF13857.6 KPA43203.1 - 2.9e-16 59.3 1.0 9.5e-14 51.3 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KPA43203.1 - 1.9e-12 47.0 2.6 1.7e-05 25.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KPA43203.1 - 3.3e-11 43.6 0.1 6.6e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.24 KPA43203.1 - 6.2e-11 42.2 0.3 1.8e-10 40.8 0.3 1.8 1 0 0 1 1 1 1 IPT/TIG domain Ank_4 PF13637.6 KPA43203.1 - 7.7e-11 42.3 0.7 4.3e-10 39.9 0.5 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA43203.1 - 9.2e-09 34.9 1.0 0.0026 18.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Cauli_VI PF01693.16 KPA43204.1 - 5e-36 122.7 5.1 1.8e-17 63.3 0.8 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 KPA43204.1 - 6.3e-35 120.5 0.0 1.4e-34 119.3 0.0 1.6 1 0 0 1 1 1 1 RNase H L-fibroin PF05849.11 KPA43204.1 - 0.042 13.1 0.1 0.095 12.0 0.0 1.5 2 0 0 2 2 2 0 Fibroin light chain (L-fibroin) dCMP_cyt_deam_1 PF00383.23 KPA43205.1 - 1.2e-08 34.7 0.1 2.3e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KPA43205.1 - 0.0016 18.2 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 MafB19-like deaminase 6PF2K PF01591.18 KPA43206.1 - 2e-66 223.5 0.0 6.8e-47 159.6 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KPA43206.1 - 1.5e-26 93.3 0.1 3.1e-22 79.2 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KPA43206.1 - 0.012 15.8 0.1 0.099 12.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 KPA43206.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sof1 PF04158.14 KPA43207.1 - 1.5e-30 105.3 14.1 3e-30 104.3 14.1 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KPA43207.1 - 1.4e-27 95.3 15.2 5.2e-06 27.1 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA43207.1 - 1.5e-11 44.4 1.0 0.018 15.3 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPA43207.1 - 0.00018 21.4 0.1 0.025 14.5 0.1 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KPA43207.1 - 0.0011 18.0 0.0 0.73 8.7 0.0 3.3 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KPA43207.1 - 0.0016 17.0 0.9 1.2 7.6 0.0 2.8 1 1 1 3 3 3 2 Cytochrome D1 heme domain tRNA_m1G_MT PF01746.21 KPA43207.1 - 0.053 13.2 0.2 0.091 12.4 0.2 1.3 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase PLC-beta_C PF08703.10 KPA43207.1 - 0.07 13.1 7.1 0.12 12.3 7.1 1.4 1 0 0 1 1 1 0 PLC-beta C terminal RNA_pol_A_bac PF01000.26 KPA43208.1 - 1.5e-33 115.5 0.0 2.3e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KPA43208.1 - 3.5e-17 61.6 0.0 4.7e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.27 KPA43209.1 - 3.5e-46 155.1 0.1 3.1e-16 59.1 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Phage_Cox PF10743.9 KPA43209.1 - 0.09 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Regulatory phage protein cox HisKA_4TM PF16926.5 KPA43209.1 - 0.8 9.3 2.7 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase tRNA-synt_2d PF01409.20 KPA43210.1 - 4.2e-48 164.0 0.2 4.6e-25 88.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KPA43210.1 - 2.9e-27 94.9 0.0 7.5e-27 93.6 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Calcipressin PF04847.12 KPA43211.1 - 9.3e-52 175.5 0.7 1.4e-51 174.9 0.7 1.2 1 0 0 1 1 1 1 Calcipressin DUF2236 PF09995.9 KPA43212.1 - 3.1e-17 63.6 5.2 3.7e-15 56.8 0.7 2.3 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2236) Neugrin PF06413.11 KPA43213.1 - 1.4e-10 41.6 0.8 1.4e-10 41.6 0.8 2.1 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 KPA43213.1 - 2.9e-05 24.3 4.8 7.7e-05 22.9 4.8 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 adh_short PF00106.25 KPA43214.1 - 2.6e-40 138.0 0.3 3.6e-40 137.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA43214.1 - 1.4e-32 113.2 0.0 1.9e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA43214.1 - 1.3e-10 41.5 1.9 9.9e-10 38.6 1.9 2.0 1 1 0 1 1 1 1 KR domain Pkinase PF00069.25 KPA43215.1 - 3.5e-05 23.3 0.0 0.19 11.1 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain TRF PF08558.10 KPA43218.1 - 5.1e-24 85.2 0.3 9e-24 84.4 0.3 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KPA43218.1 - 5.1e-05 23.4 0.0 8.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Trypan_PARP PF05887.11 KPA43218.1 - 0.0021 18.0 14.2 0.0021 18.0 14.2 3.8 4 0 0 4 4 4 1 Procyclic acidic repetitive protein (PARP) Glycos_trans_3N PF02885.17 KPA43218.1 - 0.05 13.5 0.2 29 4.6 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Myb_DNA-bind_6 PF13921.6 KPA43218.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Neisseria_TspB PF05616.13 KPA43218.1 - 0.57 8.6 6.0 1.3 7.5 6.0 1.5 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein bZIP_1 PF00170.21 KPA43220.1 - 1.7e-05 24.8 12.1 0.047 13.8 3.2 4.3 3 1 1 4 4 4 1 bZIP transcription factor TSC22 PF01166.18 KPA43220.1 - 0.00025 21.3 8.6 0.57 10.5 1.5 3.8 3 1 1 4 4 4 2 TSC-22/dip/bun family YabA PF06156.13 KPA43220.1 - 0.00041 21.0 10.0 0.015 15.9 1.2 3.5 2 2 2 4 4 4 1 Initiation control protein YabA HAP1_N PF04849.13 KPA43220.1 - 0.00053 19.3 11.1 0.002 17.4 10.5 2.3 1 1 0 1 1 1 1 HAP1 N-terminal conserved region DUF4407 PF14362.6 KPA43220.1 - 0.0034 16.8 0.9 0.0068 15.8 0.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) GIT_CC PF16559.5 KPA43220.1 - 0.005 16.7 1.0 0.27 11.2 0.0 3.2 3 1 0 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor KASH_CCD PF14662.6 KPA43220.1 - 0.02 14.7 10.0 1 9.1 3.4 3.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Herpes_BLRF2 PF05812.12 KPA43220.1 - 0.023 14.8 2.8 11 6.2 2.9 2.9 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein DivIC PF04977.15 KPA43220.1 - 0.024 14.4 8.9 0.18 11.6 0.4 3.9 3 1 1 4 4 4 0 Septum formation initiator bZIP_2 PF07716.15 KPA43220.1 - 0.039 14.0 17.1 5.2 7.2 0.2 4.5 3 1 1 4 4 4 0 Basic region leucine zipper TSNAXIP1_N PF15739.5 KPA43220.1 - 0.04 14.3 2.3 0.15 12.4 0.8 2.7 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus MbeD_MobD PF04899.12 KPA43220.1 - 0.042 14.0 7.4 0.1 12.7 0.5 3.8 2 2 2 4 4 4 0 MbeD/MobD like SlyX PF04102.12 KPA43220.1 - 0.067 13.8 5.7 7.4 7.3 0.3 3.9 3 1 1 4 4 4 0 SlyX Mod_r PF07200.13 KPA43220.1 - 0.099 12.7 6.9 1.2 9.2 0.7 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Csm1_N PF18504.1 KPA43220.1 - 0.13 12.6 9.7 9.9 6.6 0.3 4.1 3 1 2 5 5 5 0 Csm1 N-terminal domain GAS PF13851.6 KPA43220.1 - 0.15 11.4 10.2 0.66 9.3 1.8 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Ax_dynein_light PF10211.9 KPA43220.1 - 0.2 11.6 10.4 0.75 9.7 1.2 2.7 2 1 0 2 2 2 0 Axonemal dynein light chain CENP-H PF05837.12 KPA43220.1 - 0.25 11.8 9.0 0.27 11.7 2.0 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Uso1_p115_C PF04871.13 KPA43220.1 - 0.25 11.7 5.9 9.8 6.6 5.8 2.4 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.12 KPA43220.1 - 0.26 11.8 16.8 2 8.9 3.0 3.5 2 2 1 3 3 3 0 Cell division protein ZapB DUF4303 PF14136.6 KPA43220.1 - 0.3 10.8 5.2 3.7 7.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) Prefoldin_2 PF01920.20 KPA43220.1 - 0.31 11.0 3.2 7.2 6.6 0.0 3.2 2 1 1 3 3 3 0 Prefoldin subunit STAT_alpha PF01017.20 KPA43220.1 - 0.34 10.8 5.6 0.18 11.7 0.7 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain Filament PF00038.21 KPA43220.1 - 0.39 10.3 10.3 0.16 11.5 2.7 2.2 1 1 0 2 2 2 0 Intermediate filament protein TMF_TATA_bd PF12325.8 KPA43220.1 - 0.46 10.7 11.3 0.11 12.7 1.9 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KPA43220.1 - 0.51 10.4 8.0 0.11 12.5 1.0 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Taxilin PF09728.9 KPA43220.1 - 0.51 9.5 11.6 0.97 8.5 0.8 3.0 2 1 1 3 3 3 0 Myosin-like coiled-coil protein Cnn_1N PF07989.11 KPA43220.1 - 0.8 9.9 9.6 2.2 8.5 1.5 3.2 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 KPA43220.1 - 0.89 9.6 11.0 1.2e+02 2.7 11.0 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LtuB PF17455.2 KPA43220.1 - 1.2 9.8 4.9 2.2 9.0 0.4 3.1 1 1 3 4 4 3 0 Late transcription unit B CENP-F_leu_zip PF10473.9 KPA43220.1 - 1.7 8.6 11.7 2 8.5 5.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NRBF2 PF08961.10 KPA43220.1 - 1.8 8.1 10.5 0.35 10.4 1.3 2.8 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator K-box PF01486.17 KPA43220.1 - 3.6 7.8 13.3 2.1 8.6 1.0 4.1 2 2 1 3 3 3 0 K-box region Cep57_CLD_2 PF14197.6 KPA43220.1 - 7.3 6.8 16.2 0.26 11.4 3.1 3.3 4 0 0 4 4 3 0 Centrosome localisation domain of PPC89 SIKE PF05769.11 KPA43220.1 - 7.9 6.4 9.2 12 5.8 0.5 2.6 2 1 0 2 2 2 0 SIKE family HALZ PF02183.18 KPA43221.1 - 2e-07 31.1 17.7 0.0037 17.4 1.9 5.0 2 1 3 5 5 5 4 Homeobox associated leucine zipper KASH_CCD PF14662.6 KPA43221.1 - 4.3e-05 23.4 21.4 4.3e-05 23.4 21.4 1.9 2 1 0 2 2 1 1 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 KPA43221.1 - 7.4e-05 22.8 14.6 7.4e-05 22.8 14.6 3.4 2 1 1 3 3 2 1 TPR/MLP1/MLP2-like protein FPP PF05911.11 KPA43221.1 - 0.00042 18.7 23.7 0.00042 18.7 23.7 1.9 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil GAS PF13851.6 KPA43221.1 - 0.0013 18.1 13.7 0.0013 18.1 13.7 3.0 2 1 1 3 3 2 1 Growth-arrest specific micro-tubule binding MAD PF05557.13 KPA43221.1 - 0.0014 17.1 21.2 0.0014 17.1 21.2 2.1 2 0 0 2 2 1 1 Mitotic checkpoint protein DivIC PF04977.15 KPA43221.1 - 0.0026 17.5 21.0 0.042 13.6 7.5 3.6 1 1 2 3 3 3 2 Septum formation initiator KLRAQ PF10205.9 KPA43221.1 - 0.0054 16.9 9.4 0.0054 16.9 9.4 3.4 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein ADIP PF11559.8 KPA43221.1 - 0.0055 16.8 13.4 0.0055 16.8 13.4 4.5 2 2 3 5 5 3 2 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 KPA43221.1 - 0.014 14.7 16.7 0.42 9.9 8.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 KPA43221.1 - 0.017 15.5 0.9 0.017 15.5 0.9 3.7 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 KPA43221.1 - 0.021 14.8 13.1 0.021 14.8 13.1 3.4 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding DUF5082 PF16888.5 KPA43221.1 - 0.038 14.3 0.7 0.038 14.3 0.7 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) BLOC1_2 PF10046.9 KPA43221.1 - 0.062 13.6 16.6 0.31 11.4 0.5 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF745 PF05335.13 KPA43221.1 - 0.072 12.8 10.0 0.084 12.6 8.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF745) KxDL PF10241.9 KPA43221.1 - 0.22 11.8 14.0 0.099 12.9 7.4 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF1664 PF07889.12 KPA43221.1 - 0.72 9.9 10.5 1 9.4 5.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 KPA43221.1 - 0.83 10.3 28.4 0.062 13.9 4.0 3.3 2 2 2 4 4 3 0 Initiation control protein YabA Sec34 PF04136.15 KPA43221.1 - 1 9.2 13.9 1.4 8.8 2.1 2.5 1 1 1 2 2 2 0 Sec34-like family LPP PF04728.13 KPA43221.1 - 1.3 9.5 11.2 2.2 8.8 0.7 3.8 2 2 2 4 4 4 0 Lipoprotein leucine-zipper Snapin_Pallidin PF14712.6 KPA43221.1 - 1.6 9.2 13.4 0.91 10.0 3.5 2.8 1 1 1 2 2 2 0 Snapin/Pallidin DASH_Dam1 PF08653.10 KPA43221.1 - 1.8 8.4 8.5 4.4 7.2 0.2 3.4 2 2 1 3 3 3 0 DASH complex subunit Dam1 T3SSipB PF16535.5 KPA43221.1 - 2.3 8.7 13.1 2 8.9 10.3 2.3 2 1 1 3 3 2 0 Type III cell invasion protein SipB DUF948 PF06103.11 KPA43221.1 - 2.4 8.5 6.0 8.8 6.7 6.0 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Sec8_exocyst PF04048.14 KPA43221.1 - 3.1 7.7 11.4 2.5 8.0 3.6 2.9 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain DUF4407 PF14362.6 KPA43221.1 - 4.3 6.6 28.5 0.036 13.4 13.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Laminin_II PF06009.12 KPA43221.1 - 5 7.1 16.7 1.5 8.9 8.2 2.4 1 1 1 2 2 2 0 Laminin Domain II APG6_N PF17675.1 KPA43221.1 - 8.6 6.9 47.4 0.17 12.4 9.1 3.1 2 1 1 3 3 2 0 Apg6 coiled-coil region FapA PF03961.13 KPA43221.1 - 9.3 4.7 15.3 4.3 5.8 10.9 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A Smg4_UPF3 PF03467.15 KPA43223.1 - 1.4e-48 165.2 0.0 1.4e-48 165.2 0.0 3.9 3 1 1 4 4 4 1 Smg-4/UPF3 family RRM_1 PF00076.22 KPA43223.1 - 2.7e-06 27.1 0.0 4.2e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 KPA43224.1 - 1.4e-33 117.1 0.0 6.4e-29 101.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KPA43224.1 - 0.048 13.3 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 KPA43224.1 - 0.087 13.3 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Met_10 PF02475.16 KPA43225.1 - 3.8e-08 33.3 0.0 6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein EF-hand_6 PF13405.6 KPA43226.1 - 3.3e-07 29.7 1.8 0.0017 18.1 0.0 3.4 3 2 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KPA43226.1 - 5.4e-05 23.6 0.8 5.4e-05 23.6 0.8 1.7 2 0 0 2 2 2 1 EF-hand domain pair DR2241 PF18069.1 KPA43226.1 - 0.022 14.6 0.6 0.041 13.7 0.6 1.5 1 0 0 1 1 1 0 DR2241 stabilising domain EF-hand_1 PF00036.32 KPA43226.1 - 0.16 11.6 4.2 1.1 9.0 0.1 2.8 3 0 0 3 3 3 0 EF hand ORC6 PF05460.13 KPA43227.1 - 1.1e-31 110.4 0.7 2.8e-31 109.1 0.0 1.7 2 0 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) DUF1970 PF09301.10 KPA43228.1 - 6.7 7.0 7.0 30 4.9 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) adh_short_C2 PF13561.6 KPA43229.1 - 3.7e-58 196.9 0.4 4.4e-58 196.6 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA43229.1 - 8.7e-49 165.6 0.2 1e-48 165.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA43229.1 - 2.9e-09 37.1 0.1 7e-09 35.8 0.1 1.5 1 1 0 1 1 1 1 KR domain zf-ZPR1 PF03367.13 KPA43230.1 - 1.1e-112 373.1 0.0 1.9e-57 193.6 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 KPA43230.1 - 1.1 9.2 4.5 4.7 7.3 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbons DUF866 PF05907.13 KPA43231.1 - 9.7e-64 214.0 2.4 9.7e-64 214.0 2.4 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF866) Rpr2 PF04032.16 KPA43231.1 - 1.2e-12 47.9 0.3 1.2e-12 47.9 0.3 2.9 3 1 0 3 3 3 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Basic PF01586.16 KPA43231.1 - 0.53 11.5 4.5 2.6 9.3 0.3 2.8 2 0 0 2 2 2 0 Myogenic Basic domain PHD PF00628.29 KPA43231.1 - 1 9.3 7.0 2.7 8.0 1.0 2.7 2 0 0 2 2 2 0 PHD-finger Sgf11 PF08209.11 KPA43231.1 - 1 9.0 8.1 4.4 7.0 0.3 2.9 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DUF4379 PF14311.6 KPA43231.1 - 1.9 8.9 6.4 0.52 10.7 1.6 2.5 2 1 0 2 2 2 0 Probable Zinc-ribbon domain HTH_WhiA PF02650.14 KPA43232.1 - 0.019 15.3 0.4 0.062 13.6 0.4 1.9 1 0 0 1 1 1 0 WhiA C-terminal HTH domain PFEMP PF03011.15 KPA43232.1 - 0.27 11.9 0.9 1.7 9.3 0.0 2.5 2 0 0 2 2 2 0 PFEMP DBL domain PPR_2 PF13041.6 KPA43232.1 - 1.8 8.8 4.3 0.86 9.8 0.1 2.7 4 0 0 4 4 4 0 PPR repeat family GDPD PF03009.17 KPA43233.1 - 1.8e-70 237.6 0.0 3.3e-70 236.8 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KPA43233.1 - 2.9e-26 91.8 0.0 2.3e-16 60.1 0.0 4.5 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA43233.1 - 1.3e-24 86.2 0.2 8.9e-09 35.7 0.0 5.8 7 0 0 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA43233.1 - 7.2e-20 70.8 0.0 2.8e-07 30.7 0.0 4.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) SPX PF03105.19 KPA43233.1 - 1.7e-16 61.1 19.5 6e-11 42.9 0.3 4.2 4 2 1 5 5 5 3 SPX domain Ank_3 PF13606.6 KPA43233.1 - 1.1e-14 53.1 0.3 0.0034 17.8 0.0 7.7 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 KPA43233.1 - 1.5e-14 53.7 1.2 0.019 15.4 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat zf-C2H2 PF00096.26 KPA43234.1 - 8.3e-20 70.1 36.4 4.3e-06 26.9 0.1 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPA43234.1 - 1.4e-17 63.2 32.1 2.1e-06 27.9 0.6 6.0 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPA43234.1 - 4.3e-06 27.1 44.9 0.021 15.7 1.3 5.9 7 0 0 7 7 7 4 C2H2-type zinc finger FOXP-CC PF16159.5 KPA43234.1 - 0.0036 17.9 9.6 9.3 7.0 0.3 4.8 2 1 2 4 4 4 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KPA43234.1 - 0.0045 17.3 9.5 1.9 8.9 6.0 3.1 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KPA43234.1 - 0.014 15.1 2.0 0.014 15.1 2.0 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-TRAF PF02176.18 KPA43234.1 - 0.026 15.2 15.5 0.034 14.8 2.4 3.4 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 KPA43234.1 - 0.35 11.0 0.1 0.35 11.0 0.1 3.4 1 1 2 3 3 3 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 KPA43234.1 - 0.53 10.7 9.2 21 5.5 0.0 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Aminotran_1_2 PF00155.21 KPA43235.1 - 9.9e-05 21.7 0.0 0.00034 19.9 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Ribosomal_L4 PF00573.22 KPA43236.1 - 2.1e-35 122.1 0.4 3.8e-35 121.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KPA43236.1 - 6.3e-27 93.5 1.0 1.5e-26 92.2 1.0 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain DUF4428 PF14471.6 KPA43236.1 - 0.1 12.5 0.1 41 4.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-C2H2 PF00096.26 KPA43237.1 - 5.5e-06 26.5 11.7 8e-05 22.9 2.4 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA43237.1 - 0.0021 18.7 2.2 0.0021 18.7 2.2 4.0 5 0 0 5 5 5 1 C2H2-type zinc finger zf-Di19 PF05605.12 KPA43237.1 - 0.0056 16.9 7.9 0.0056 16.9 7.9 2.9 3 1 1 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KPA43237.1 - 0.017 15.4 2.5 0.017 15.4 2.5 2.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PGA2 PF07543.12 KPA43238.1 - 1.4e-34 119.0 0.3 2e-34 118.5 0.3 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 TMEM70 PF06979.12 KPA43238.1 - 0.074 13.5 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex GTP_EFTU PF00009.27 KPA43239.1 - 1.7e-56 190.9 0.1 2.3e-56 190.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KPA43239.1 - 4.3e-25 88.2 0.0 9e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KPA43239.1 - 1.7e-16 60.3 3.7 3.4e-16 59.4 3.7 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KPA43239.1 - 1.7e-05 24.9 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA43239.1 - 0.0018 18.2 0.1 0.0043 17.0 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KPA43239.1 - 0.025 14.2 0.2 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KPA43239.1 - 0.14 11.9 0.2 17 5.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S14 PF00253.21 KPA43240.1 - 2.9e-15 55.8 2.9 6.3e-15 54.7 2.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 KPA43240.1 - 0.0095 15.8 0.7 0.014 15.3 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) Thioredoxin PF00085.20 KPA43241.1 - 1.6e-58 195.1 0.3 4.2e-30 103.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KPA43241.1 - 1.9e-25 89.5 0.1 1.9e-25 89.5 0.1 3.1 4 0 0 4 4 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KPA43241.1 - 8.5e-18 64.8 0.1 5.7e-10 39.6 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KPA43241.1 - 2e-17 63.5 0.0 7.2e-08 32.1 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KPA43241.1 - 7.3e-11 42.1 0.0 0.00016 21.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KPA43241.1 - 1.4e-10 41.3 0.2 0.00011 22.4 0.0 3.3 3 1 0 3 3 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KPA43241.1 - 2.5e-08 33.9 0.1 0.00077 19.4 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 KPA43241.1 - 2e-06 27.6 1.4 0.022 14.4 0.5 2.5 1 1 1 2 2 2 2 Redoxin TraF PF13728.6 KPA43241.1 - 2.3e-06 27.6 0.4 0.027 14.3 0.0 2.7 3 0 0 3 3 3 2 F plasmid transfer operon protein ERp29_N PF07912.13 KPA43241.1 - 0.00014 22.0 0.0 0.49 10.5 0.0 2.6 2 0 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_9 PF14595.6 KPA43241.1 - 0.0004 20.1 0.8 0.56 10.0 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.6 KPA43241.1 - 0.0027 17.7 0.2 0.69 10.0 0.0 2.9 3 0 0 3 3 2 1 Thioredoxin domain Glutaredoxin PF00462.24 KPA43241.1 - 0.0029 17.8 1.7 0.95 9.7 0.1 3.2 2 2 0 2 2 2 1 Glutaredoxin Condensin2nSMC PF12422.8 KPA43241.1 - 0.017 15.3 0.1 0.031 14.5 0.1 1.3 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit HyaE PF07449.11 KPA43241.1 - 0.021 14.8 0.0 0.58 10.1 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 KPA43241.1 - 0.072 13.3 7.0 9.4 6.4 0.1 4.3 3 2 2 5 5 5 0 Thioredoxin Apolipoprotein PF01442.18 KPA43241.1 - 0.2 11.5 9.0 0.065 13.1 3.3 2.8 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain Phe_tRNA-synt_N PF02912.18 KPA43241.1 - 5.8 6.9 9.1 0.32 11.0 2.0 2.3 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain HSBP1 PF06825.12 KPA43242.1 - 8.1e-18 64.0 0.1 1e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Apolipoprotein PF01442.18 KPA43242.1 - 0.005 16.7 0.1 0.0058 16.5 0.1 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KPA43242.1 - 0.012 15.7 0.2 0.014 15.4 0.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 KPA43242.1 - 0.015 15.6 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Matrilin_ccoil PF10393.9 KPA43242.1 - 0.029 14.2 0.1 0.13 12.2 0.1 1.8 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1664 PF07889.12 KPA43242.1 - 0.037 14.1 0.1 0.044 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ANAPC4 PF12896.7 KPA43242.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF2277 PF10041.9 KPA43242.1 - 0.14 12.5 0.5 0.3 11.5 0.5 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) zf-rbx1 PF12678.7 KPA43243.1 - 8.4e-10 38.8 0.6 8.4e-10 38.8 0.6 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KPA43243.1 - 7e-07 29.5 8.1 3.6e-06 27.2 8.0 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KPA43243.1 - 2.2e-06 27.4 0.6 3.8e-06 26.7 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPA43243.1 - 3.1e-06 27.0 0.5 6.4e-06 26.0 0.5 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KPA43243.1 - 7.4e-06 25.7 5.0 3.4e-05 23.6 1.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA43243.1 - 1.3e-05 25.1 1.1 0.00013 21.9 0.1 2.8 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KPA43243.1 - 0.00015 21.5 0.7 0.00015 21.5 0.7 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KPA43243.1 - 0.0016 18.2 1.1 0.0016 18.2 1.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PQ-loop PF04193.14 KPA43243.1 - 0.0033 17.2 0.3 0.01 15.6 0.3 1.9 1 0 0 1 1 1 1 PQ loop repeat Zn_ribbon_17 PF17120.5 KPA43243.1 - 0.008 15.8 0.5 0.021 14.5 0.5 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KPA43243.1 - 0.017 14.9 0.4 0.017 14.9 0.4 3.2 3 0 0 3 3 3 0 RING-like zinc finger zf-ANAPC11 PF12861.7 KPA43243.1 - 0.12 12.4 3.9 0.054 13.5 0.7 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_clus PF00172.18 KPA43244.1 - 5.9e-10 39.1 12.3 1e-09 38.3 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.8 KPA43244.1 - 1.6 7.8 15.2 2.8 7.1 15.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SPICE PF15678.5 KPA43244.1 - 3.8 6.7 5.1 7 5.9 5.1 1.3 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression Thioredoxin_10 PF17991.1 KPA43245.1 - 0.04 14.5 0.1 0.057 14.0 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin like C-terminal domain Rhomboid PF01694.22 KPA43246.1 - 3.2e-37 127.9 5.1 3.2e-37 127.9 5.1 1.7 2 0 0 2 2 2 1 Rhomboid family ABC2_membrane_5 PF13346.6 KPA43246.1 - 0.061 12.9 4.5 0.19 11.3 0.2 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4381 PF14316.6 KPA43246.1 - 3.3 7.9 4.4 2.2 8.5 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Baculo_11_kDa PF06143.11 KPA43246.1 - 9 6.0 5.8 0.53 9.9 0.1 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family DNA_pol_B PF00136.21 KPA43247.1 - 1.8e-148 495.0 1.8 2.6e-148 494.5 1.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KPA43247.1 - 2e-78 263.9 0.3 1.4e-77 261.2 0.2 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KPA43247.1 - 1.2e-17 64.1 7.0 3.3e-17 62.7 7.0 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KPA43247.1 - 0.00033 19.7 0.2 0.0086 15.0 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 KPA43247.1 - 0.0013 18.8 0.3 0.013 15.5 0.3 2.6 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KPA43247.1 - 0.0048 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DUF2614 PF11023.8 KPA43247.1 - 0.079 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain C1_1 PF00130.22 KPA43247.1 - 0.25 11.3 10.3 0.079 12.9 1.1 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ELFV_dehydrog PF00208.21 KPA43248.1 - 2.8e-81 272.8 2.5 3.4e-81 272.5 2.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KPA43248.1 - 1.9e-51 173.3 0.0 3.4e-51 172.5 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 KPA43248.1 - 0.07 13.6 0.1 0.47 10.9 0.0 2.3 3 0 0 3 3 3 0 Putative NAD(P)-binding CoA_transf_3 PF02515.17 KPA43249.1 - 4.6e-68 230.0 0.0 6.1e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Dynamin_M PF01031.20 KPA43250.1 - 6.8e-102 340.5 0.0 1.4e-101 339.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KPA43250.1 - 4.3e-57 192.8 0.0 8e-57 191.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KPA43250.1 - 1.2e-29 102.2 5.6 2.9e-29 101.1 5.6 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KPA43250.1 - 2.1e-06 27.8 0.2 4.6e-05 23.5 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KPA43250.1 - 0.032 14.0 0.2 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.18 KPA43250.1 - 0.11 12.0 0.1 18 4.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B WD40 PF00400.32 KPA43251.1 - 1.3e-20 73.4 9.0 0.00014 22.5 0.0 6.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA43251.1 - 3.9e-08 33.5 0.4 0.48 10.7 0.0 5.4 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CLTH PF10607.9 KPA43251.1 - 0.0067 16.3 0.2 0.028 14.3 0.0 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain WD40_like PF17005.5 KPA43251.1 - 0.0095 15.3 0.0 0.024 14.0 0.0 1.5 1 1 0 1 1 1 1 WD40-like domain Cytochrom_D1 PF02239.16 KPA43251.1 - 0.082 11.4 0.0 6.5 5.2 0.0 2.7 2 1 0 2 2 2 0 Cytochrome D1 heme domain HK_sensor PF16750.5 KPA43251.1 - 0.12 12.7 0.1 0.31 11.3 0.1 1.6 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase SPX PF03105.19 KPA43251.1 - 1.6 8.6 7.2 2.5 7.9 7.2 1.3 1 0 0 1 1 1 0 SPX domain DUF4106 PF13388.6 KPA43251.1 - 3.8 6.6 7.3 5.8 6.0 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Flexi_CP_N PF08358.10 KPA43252.1 - 2.9 8.0 4.7 8.8 6.4 0.4 2.6 2 0 0 2 2 2 0 Carlavirus coat SRP-alpha_N PF04086.13 KPA43252.1 - 5.2 6.9 17.1 0.05 13.5 6.5 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal CAS_CSE1 PF03378.15 KPA43253.1 - 3.8e-175 582.7 0.1 2e-174 580.3 0.0 2.2 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KPA43253.1 - 5.6e-149 496.0 4.7 8.2e-149 495.4 4.7 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KPA43253.1 - 2.4e-13 49.8 0.6 1.1e-12 47.6 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3384 PF11864.8 KPA43254.1 - 1.1e-142 476.4 1.7 2.1e-141 472.1 0.0 3.0 3 1 1 4 4 4 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KPA43254.1 - 4.8e-53 179.5 0.0 7.6e-53 178.8 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KPA43254.1 - 2.4e-39 135.5 2.6 4.1e-34 118.2 0.0 3.6 4 0 0 4 4 4 3 Tuberin DUF5576 PF17739.1 KPA43254.1 - 0.12 12.4 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5576) Acetyltransf_7 PF13508.7 KPA43255.1 - 8e-07 29.4 0.0 1.1e-05 25.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA43255.1 - 1.2e-05 25.5 0.0 7.2e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA43255.1 - 0.00025 21.0 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA43255.1 - 0.00074 19.6 0.0 0.05 13.7 0.0 2.8 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA43255.1 - 0.0021 18.0 0.1 0.026 14.5 0.1 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KPA43255.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CENP-I PF07778.11 KPA43256.1 - 1.4e-33 116.4 0.0 5.6e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Mis6 SPO11_like PF03533.14 KPA43256.1 - 0.19 11.8 0.1 14 5.8 0.0 2.5 2 0 0 2 2 2 0 SPO11 homologue ABC_tran PF00005.27 KPA43257.1 - 4.7e-15 56.3 0.0 2.9e-14 53.7 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KPA43257.1 - 4.1e-11 43.2 1.6 0.00023 21.1 0.5 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 KPA43257.1 - 0.00058 17.5 0.2 0.00077 17.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 KPA43257.1 - 0.00073 19.2 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KPA43257.1 - 0.0026 17.2 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPA43257.1 - 0.0052 17.3 0.1 0.0076 16.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KPA43257.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 KPA43257.1 - 0.018 14.8 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KPA43257.1 - 0.022 15.1 0.2 0.067 13.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KPA43257.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KPA43257.1 - 0.034 14.4 1.2 0.039 14.2 0.2 1.5 2 0 0 2 2 1 0 AAA domain AAA PF00004.29 KPA43257.1 - 0.049 14.0 0.1 0.19 12.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KPA43257.1 - 0.05 13.2 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KPA43257.1 - 0.052 13.0 0.3 0.15 11.5 0.3 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KPA43257.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KPA43257.1 - 0.069 13.5 0.9 0.15 12.4 0.9 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 KPA43257.1 - 0.086 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KPA43257.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KPA43257.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KPA43257.1 - 0.17 11.8 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 KPA43257.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.6 KPA43257.1 - 0.18 11.8 0.0 0.64 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain DNA_pol_E_B PF04042.16 KPA43258.1 - 4.8e-48 163.3 0.0 6.4e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KPA43258.1 - 3.7e-41 140.3 0.0 1.5e-40 138.3 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase delta subunit OB-fold domain Ribosomal_L18A PF01775.17 KPA43259.1 - 0.082 13.0 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PALP PF00291.25 KPA43260.1 - 1.8e-65 221.3 0.2 2.1e-65 221.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CENP-S PF15630.6 KPA43261.1 - 6.6e-36 122.6 0.0 9.7e-36 122.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KPA43261.1 - 2.4e-07 30.9 0.0 3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KPA43261.1 - 0.00039 20.4 0.0 0.00074 19.5 0.0 1.4 1 1 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.16 KPA43261.1 - 0.0037 17.3 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TAF PF02969.17 KPA43261.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) MARVEL PF01284.23 KPA43262.1 - 0.00018 21.6 17.4 0.0016 18.5 17.7 2.0 1 1 0 1 1 1 1 Membrane-associating domain DUF3422 PF11902.8 KPA43262.1 - 0.096 11.8 3.3 4.7 6.2 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3422) DUF4233 PF14017.6 KPA43262.1 - 0.87 10.0 6.3 0.74 10.2 3.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Phage_holin_8 PF16931.5 KPA43262.1 - 1 9.3 5.9 1.9 8.4 5.9 1.4 1 0 0 1 1 1 0 Putative phage holin DUF3402 PF11882.8 KPA43263.1 - 1.1e-213 710.6 0.3 1.4e-213 710.1 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KPA43263.1 - 9.5e-97 323.6 0.1 1.5e-96 323.0 0.1 1.3 1 0 0 1 1 1 1 N1221-like protein DUF2011 PF09428.10 KPA43264.1 - 3.8e-21 75.1 0.5 1.3e-19 70.2 0.0 2.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) NPIP PF06409.11 KPA43264.1 - 3.4 6.7 9.1 6 5.9 9.1 1.4 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) SPT16 PF08644.11 KPA43264.1 - 5.8 7.1 11.8 3.7 7.7 9.8 1.6 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF4407 PF14362.6 KPA43264.1 - 8.9 5.6 11.8 16 4.8 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NDT80_PhoG PF05224.12 KPA43265.1 - 3.8e-34 118.5 0.0 8.1e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family IBR PF01485.21 KPA43266.1 - 9.5e-21 73.8 37.4 2.2e-14 53.4 4.8 4.2 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 KPA43266.1 - 9.7e-17 61.3 0.0 2e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KPA43266.1 - 0.00043 20.5 8.1 0.00043 20.5 8.1 4.0 3 1 1 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.6 KPA43266.1 - 0.00044 20.2 6.1 0.00044 20.2 6.1 3.8 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 KPA43266.1 - 0.0022 17.9 6.6 0.0022 17.9 6.6 3.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KPA43266.1 - 0.0054 16.9 2.3 0.0054 16.9 2.3 4.2 4 1 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KPA43266.1 - 0.0095 15.7 7.6 0.029 14.1 7.6 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KPA43266.1 - 0.43 10.5 37.0 0.024 14.5 8.8 4.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PAP2 PF01569.21 KPA43267.1 - 7.4e-12 45.2 7.2 1.5e-11 44.2 4.7 2.4 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 KPA43267.1 - 0.0011 19.1 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 Divergent PAP2 family UbiA PF01040.18 KPA43267.1 - 0.26 10.5 11.9 0.011 15.1 5.2 1.8 1 1 0 2 2 2 0 UbiA prenyltransferase family Grg1 PF11034.8 KPA43269.1 - 2.2e-29 101.5 9.5 2.4e-29 101.3 9.5 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 MT0933_antitox PF14013.6 KPA43269.1 - 0.018 15.3 5.3 0.027 14.8 5.3 1.3 1 1 0 1 1 1 0 MT0933-like antitoxin protein EBP PF05241.12 KPA43270.1 - 2.2e-71 239.0 8.2 2.5e-71 238.8 8.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein NAD_kinase PF01513.21 KPA43271.1 - 4.1e-70 236.3 0.0 6.2e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KPA43271.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain UL42 PF17638.2 KPA43273.1 - 0.0012 18.8 3.4 0.0012 18.8 3.4 1.7 1 1 0 1 1 1 1 HCMV UL42 NOA36 PF06524.12 KPA43273.1 - 0.28 10.5 9.4 0.41 9.9 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 KPA43273.1 - 8 6.0 13.7 0.13 11.9 5.5 1.9 2 0 0 2 2 2 0 PPP4R2 IF4E PF01652.18 KPA43274.1 - 1.3e-35 122.5 0.0 1.7e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E zf-C2HE PF16278.5 KPA43275.1 - 2.8e-17 62.9 0.2 7e-17 61.6 0.2 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KPA43275.1 - 4.6e-15 56.1 4.4 3.5e-14 53.3 4.4 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KPA43275.1 - 5.9e-15 55.8 0.1 1.3e-14 54.7 0.1 1.5 1 1 0 1 1 1 1 HIT domain NOA36 PF06524.12 KPA43276.1 - 6.3 6.0 8.7 7 5.9 8.7 1.1 1 0 0 1 1 1 0 NOA36 protein Kinesin PF00225.23 KPA43277.1 - 1.3e-115 385.9 0.1 2.2e-115 385.1 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPA43277.1 - 1.1e-24 87.1 0.8 2.2e-24 86.1 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Spc7 PF08317.11 KPA43277.1 - 0.0049 15.8 7.6 0.01 14.7 7.6 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein IL11 PF07400.11 KPA43277.1 - 0.03 14.0 0.4 0.087 12.5 0.4 1.8 1 0 0 1 1 1 0 Interleukin 11 PriC PF07445.12 KPA43277.1 - 0.044 13.7 7.8 0.1 12.5 7.8 1.6 1 0 0 1 1 1 0 Primosomal replication protein priC YabA PF06156.13 KPA43277.1 - 0.27 11.9 12.1 3.1 8.5 0.1 4.0 3 1 1 4 4 4 0 Initiation control protein YabA Tau95 PF09734.9 KPA43277.1 - 0.3 11.9 2.8 0.5 11.2 1.6 1.9 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF87 PF01935.17 KPA43277.1 - 0.72 9.9 0.0 0.72 9.9 0.0 3.4 3 1 0 3 3 3 0 Helicase HerA, central domain Noggin PF05806.12 KPA43277.1 - 0.81 9.6 2.5 24 4.7 0.2 2.8 3 0 0 3 3 3 0 Noggin HA2 PF04408.23 KPA43278.1 - 1.7e-17 63.6 0.8 1.6e-16 60.6 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KPA43278.1 - 1.4e-16 60.6 0.0 3e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KPA43278.1 - 3.2e-16 59.7 0.1 2.4e-15 56.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPA43278.1 - 1.2e-10 41.4 0.1 3.7e-10 39.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.22 KPA43278.1 - 1.4e-06 28.6 0.0 3.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.6 KPA43278.1 - 0.00089 19.5 0.6 0.0046 17.2 0.6 2.2 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KPA43278.1 - 0.0013 18.1 0.2 0.004 16.5 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 KPA43278.1 - 0.0076 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KPA43278.1 - 0.011 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 KPA43278.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein dsRBD2 PF17842.1 KPA43278.1 - 0.016 15.4 0.1 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 DND1_DSRM PF14709.7 KPA43278.1 - 0.018 15.3 0.3 0.051 13.8 0.0 1.9 2 0 0 2 2 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.6 KPA43278.1 - 0.046 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KPA43278.1 - 0.18 12.3 4.9 0.14 12.6 0.6 2.9 2 1 0 2 2 2 0 AAA domain IHABP4_N PF16174.5 KPA43278.1 - 0.39 11.3 5.6 0.068 13.8 0.9 2.1 2 0 0 2 2 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Arm PF00514.23 KPA43279.1 - 1.2e-98 320.5 14.6 7.4e-14 51.2 0.2 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KPA43279.1 - 1.1e-27 96.3 2.0 1.1e-27 96.3 2.0 2.1 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 KPA43279.1 - 1.3e-24 85.5 4.1 3.2e-24 84.2 3.7 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KPA43279.1 - 6.6e-23 80.8 8.2 7.4e-09 35.9 0.1 6.4 4 1 2 6 6 6 5 HEAT-like repeat HEAT_2 PF13646.6 KPA43279.1 - 1.1e-19 70.6 0.1 2.1e-08 34.4 0.0 5.3 1 1 2 4 4 4 4 HEAT repeats HEAT PF02985.22 KPA43279.1 - 4.5e-19 66.9 2.1 1.7e-05 24.7 0.0 7.1 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 KPA43279.1 - 5.3e-08 32.6 0.0 0.076 12.5 0.0 4.3 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 KPA43279.1 - 1.2e-05 24.1 0.0 0.00084 18.0 0.0 2.4 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KPA43279.1 - 0.0001 22.4 0.0 2 8.5 0.0 4.4 3 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.16 KPA43279.1 - 0.00063 20.2 0.2 1.7 9.6 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 KPA43279.1 - 0.00086 19.4 0.0 1.6 8.8 0.0 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 KPA43279.1 - 0.0045 17.2 5.1 3.1 8.1 0.0 5.0 3 2 3 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 KPA43279.1 - 0.017 14.7 0.0 5.6 6.5 0.0 3.8 2 2 3 5 5 5 0 Nucleolar pre-ribosomal-associated protein 1 Glycos_trans_3N PF02885.17 KPA43279.1 - 0.031 14.1 0.0 7.2 6.5 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain NUSAP PF16006.5 KPA43279.1 - 6.8 6.4 6.4 9.6 5.9 6.4 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein Vanabin-2 PF11437.8 KPA43280.1 - 0.86 9.8 7.2 0.25 11.5 4.3 1.5 2 0 0 2 2 2 0 Vanadium-binding protein 2 Gln-synt_C PF00120.24 KPA43281.1 - 2.5e-68 230.6 0.0 3.7e-68 230.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KPA43281.1 - 2.3e-15 57.2 0.0 5.3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Gln-synt_N_2 PF16952.5 KPA43281.1 - 0.00016 21.5 0.0 0.00052 19.8 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase N-terminal domain Response_reg PF00072.24 KPA43282.1 - 1.3e-27 96.2 0.5 3e-27 95.0 0.5 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KPA43282.1 - 3.3e-26 92.0 0.8 8.8e-24 84.2 0.8 2.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KPA43282.1 - 1.6e-14 53.7 0.0 4.8e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain dCache_1 PF02743.18 KPA43282.1 - 0.00062 19.6 2.5 0.00062 19.6 2.5 2.5 2 1 0 2 2 2 1 Cache domain HAMP PF00672.25 KPA43282.1 - 0.001 19.4 0.0 0.018 15.4 0.0 2.6 2 0 0 2 2 2 1 HAMP domain Cnn_1N PF07989.11 KPA43282.1 - 0.14 12.3 0.7 0.31 11.2 0.7 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 CDC50 PF03381.15 KPA43283.1 - 4.2e-100 334.9 0.0 5.1e-100 334.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.11 KPA43284.1 - 7.4e-56 188.5 0.1 7.4e-56 188.5 0.1 2.8 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KPA43284.1 - 1.7e-55 187.2 0.6 5.3e-55 185.6 0.6 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KPA43284.1 - 7.3e-25 87.9 0.0 1.7e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KPA43284.1 - 7.3e-15 55.2 1.4 1.3e-14 54.4 0.2 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Activator-TraM PF11657.8 KPA43284.1 - 0.12 12.2 0.7 40 4.0 0.0 3.3 3 0 0 3 3 3 0 Transcriptional activator TraM CMD PF02627.20 KPA43285.1 - 1.6e-09 37.6 0.0 7.9e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Methyltransf_17 PF12692.7 KPA43285.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase PRMT5_C PF17286.2 KPA43285.1 - 0.16 11.9 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Pkinase PF00069.25 KPA43287.1 - 3.7e-10 39.6 0.0 5.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KPA43287.1 - 2.3e-07 30.4 0.0 2e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPA43287.1 - 6.7e-07 29.5 0.1 0.0047 16.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KPA43287.1 - 0.0001 21.7 0.0 0.00021 20.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 KPA43287.1 - 0.00013 21.6 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KPA43287.1 - 0.11 11.3 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Aldo_ket_red PF00248.21 KPA43288.1 - 2.2e-08 33.6 0.0 3.1e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 KPA43289.1 - 1.3e-51 174.3 1.0 1.5e-51 174.1 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 KPA43289.1 - 0.032 15.0 0.1 0.058 14.1 0.1 1.4 1 0 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 KPA43290.1 - 1.5e-58 197.8 0.0 2.2e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator PAN_4 PF14295.6 KPA43291.1 - 0.0087 15.9 0.8 0.021 14.7 0.8 1.6 1 0 0 1 1 1 1 PAN domain Mpp10 PF04006.12 KPA43292.1 - 4.2e-111 372.3 55.3 7.9e-111 371.4 55.3 1.4 1 1 0 1 1 1 1 Mpp10 protein SHNi-TPR PF10516.9 KPA43293.1 - 1.9e-12 46.4 0.8 4.7e-12 45.2 0.1 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.17 KPA43293.1 - 0.00013 21.8 4.8 0.036 14.2 0.7 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPA43293.1 - 0.00013 22.2 2.1 0.0048 17.2 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPA43293.1 - 0.00093 19.8 1.3 0.0086 16.7 0.5 3.0 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPA43293.1 - 0.16 12.9 0.7 0.98 10.4 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KPA43293.1 - 0.16 11.8 1.1 12 5.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KPA43293.1 - 0.29 11.2 1.2 0.49 10.4 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MscS_porin PF12795.7 KPA43293.1 - 4.1 6.9 13.0 0.87 9.1 1.9 3.6 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain DHquinase_I PF01487.15 KPA43294.1 - 8e-43 147.3 0.0 1.6e-42 146.3 0.0 1.5 2 0 0 2 2 2 1 Type I 3-dehydroquinase Fungal_trans PF04082.18 KPA43295.1 - 7.4e-22 77.6 0.0 1.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KPA43296.1 - 4.7e-31 108.0 55.0 5e-31 107.9 53.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA43296.1 - 2.8e-06 26.5 12.3 2.8e-06 26.5 12.3 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA43297.1 - 4.4e-05 22.6 14.5 4.4e-05 22.6 14.5 4.2 2 2 2 4 4 4 3 Major Facilitator Superfamily NAD_binding_6 PF08030.12 KPA43298.1 - 4.7e-19 69.0 0.0 6.7e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KPA43298.1 - 5.4e-15 55.6 14.1 5.4e-15 55.6 14.1 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KPA43298.1 - 1.7e-07 31.3 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KPA43298.1 - 0.041 14.5 0.0 8 7.2 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain adh_short_C2 PF13561.6 KPA43299.1 - 1.4e-36 126.2 0.3 4.8e-30 104.9 0.1 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA43299.1 - 1.7e-36 125.6 0.3 3.7e-36 124.4 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA43299.1 - 3.6e-08 33.5 1.0 2.6e-07 30.7 1.0 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA43299.1 - 0.00034 20.1 0.1 0.0036 16.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KPA43300.1 - 1.1e-58 198.6 2.3 2.8e-58 197.2 2.3 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA43300.1 - 9.4e-39 132.9 1.5 2.5e-38 131.5 1.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA43300.1 - 4.4e-09 36.5 1.2 6.5e-08 32.7 1.2 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA43300.1 - 0.00086 18.8 0.1 0.002 17.6 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA43300.1 - 0.003 17.0 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1638 PF07796.11 KPA43300.1 - 0.0066 16.5 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1638) Sacchrp_dh_NADP PF03435.18 KPA43300.1 - 0.012 15.9 0.1 0.017 15.4 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KPA43300.1 - 0.037 13.6 0.4 0.037 13.6 0.4 1.5 2 0 0 2 2 2 0 NmrA-like family F420_oxidored PF03807.17 KPA43300.1 - 0.061 13.9 0.3 0.14 12.8 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KPA43300.1 - 0.096 12.0 0.2 0.21 10.9 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-CCHC_5 PF14787.6 KPA43300.1 - 0.13 12.0 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger 3HCDH_N PF02737.18 KPA43300.1 - 0.16 11.9 0.3 0.25 11.2 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CCDC92 PF14916.6 KPA43301.1 - 0.0021 17.8 0.1 0.0021 17.8 0.1 2.8 3 0 0 3 3 3 1 Coiled-coil domain of unknown function Filament PF00038.21 KPA43301.1 - 0.0072 15.9 11.2 0.0072 15.9 11.2 3.6 1 1 0 3 3 3 1 Intermediate filament protein DUF4423 PF14394.6 KPA43301.1 - 0.043 13.5 0.3 0.043 13.5 0.3 3.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4423) Lys-AminoMut_A PF09043.11 KPA43301.1 - 0.071 11.6 2.8 0.17 10.3 2.8 1.6 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Augurin PF15187.6 KPA43301.1 - 0.078 13.2 0.9 0.28 11.4 0.9 1.9 1 0 0 1 1 1 0 Oesophageal cancer-related gene 4 Trimer_CC PF08954.11 KPA43301.1 - 1 9.0 9.2 1.2 8.7 0.9 3.7 3 0 0 3 3 3 0 Trimerisation motif Atg14 PF10186.9 KPA43301.1 - 1.7 7.6 34.3 0.073 12.1 8.4 3.1 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 KPA43301.1 - 5 7.8 38.4 0.2 12.3 11.2 4.8 4 1 1 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FliE PF02049.18 KPA43301.1 - 5.5 7.2 10.5 39 4.5 4.5 3.9 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE DUF1129 PF06570.11 KPA43302.1 - 0.035 13.6 1.7 0.072 12.6 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) RTA1 PF04479.13 KPA43303.1 - 2.5e-42 144.8 10.1 3.4e-42 144.4 10.1 1.2 1 0 0 1 1 1 1 RTA1 like protein TMEM192 PF14802.6 KPA43303.1 - 0.74 8.9 4.6 0.99 8.5 0.4 2.5 3 1 0 3 3 3 0 TMEM192 family DUF3188 PF11384.8 KPA43303.1 - 3.7 7.3 6.6 0.9 9.3 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Arrestin_N PF00339.29 KPA43304.1 - 3.1e-16 59.8 0.0 1.3e-10 41.5 0.0 3.2 3 0 0 3 3 3 3 Arrestin (or S-antigen), N-terminal domain PGAP1 PF07819.13 KPA43305.1 - 3.8e-08 33.3 0.0 5.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KPA43305.1 - 2.7e-06 27.2 0.0 2.5e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA43305.1 - 7.2e-05 23.5 4.1 9e-05 23.2 3.5 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KPA43305.1 - 7.4e-05 22.4 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KPA43305.1 - 0.00027 20.9 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 KPA43305.1 - 0.00075 19.4 0.2 0.0011 18.8 0.2 1.3 1 0 0 1 1 1 1 Serine hydrolase LCAT PF02450.15 KPA43305.1 - 0.0017 17.6 0.0 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KPA43305.1 - 0.022 14.0 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PMP1_2 PF08114.11 KPA43306.1 - 0.0042 16.8 0.6 0.0093 15.7 0.6 1.5 1 0 0 1 1 1 1 ATPase proteolipid family LapA_dom PF06305.11 KPA43306.1 - 1.8 8.4 4.1 0.64 9.9 1.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_MOT1 PF16983.5 KPA43307.1 - 6.8e-66 219.6 25.7 1.6e-35 121.9 6.9 2.5 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily Forkhead PF00250.18 KPA43308.1 - 2.5e-13 50.1 0.0 4.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KPA43308.1 - 0.00027 21.2 0.0 0.00053 20.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain SAM_2 PF07647.17 KPA43309.1 - 1.1e-13 51.1 0.0 2.3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KPA43309.1 - 2.6e-12 46.4 0.0 6e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPA43309.1 - 8.2e-12 44.5 0.0 1.7e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KPA43309.1 - 1.3e-09 38.5 0.0 3.8e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 KPA43309.1 - 0.00065 20.1 0.1 0.0021 18.5 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.17 KPA43309.1 - 0.00084 19.0 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.6 KPA43309.1 - 0.012 15.8 0.0 0.072 13.4 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain SAM_1 PF00536.30 KPA43309.1 - 0.052 14.0 0.0 0.099 13.1 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) zf-MIZ PF02891.20 KPA43310.1 - 1e-10 41.2 1.0 4.7e-10 39.1 1.0 2.1 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KPA43310.1 - 0.00032 20.4 0.1 0.0009 19.0 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TPR_10 PF13374.6 KPA43310.1 - 0.01 15.7 0.6 0.023 14.6 0.6 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2779 PF11074.8 KPA43310.1 - 0.2 12.1 0.1 8.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) Methyltransf_25 PF13649.6 KPA43313.1 - 3.3e-18 66.2 0.1 3e-17 63.1 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA43313.1 - 7.1e-17 61.6 0.0 1.6e-16 60.4 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA43313.1 - 6.7e-16 58.7 0.2 9.3e-15 55.1 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA43313.1 - 2.3e-13 50.7 0.1 2.9e-12 47.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA43313.1 - 8e-12 45.0 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KPA43313.1 - 2.3e-10 40.5 0.0 3.7e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KPA43313.1 - 1.9e-08 34.3 0.0 4.5e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KPA43313.1 - 3.8e-05 23.3 0.0 0.0001 21.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 KPA43313.1 - 0.0014 18.8 0.0 0.0023 18.1 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 KPA43313.1 - 0.021 14.1 0.0 0.027 13.7 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KPA43313.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 KPA43313.1 - 0.12 13.4 0.1 0.31 12.1 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain HAD_2 PF13419.6 KPA43314.1 - 0.00023 21.3 0.0 0.00049 20.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Ribosomal_L5e PF17144.4 KPA43315.1 - 2e-80 268.5 0.6 3.4e-80 267.8 0.6 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KPA43315.1 - 1.1e-33 116.1 8.0 1.1e-33 116.1 8.0 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KPA43315.1 - 0.02 15.2 1.6 0.028 14.8 0.1 1.9 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast FmdE PF02663.14 KPA43315.1 - 0.49 10.4 7.6 18 5.3 5.8 3.0 2 1 1 3 3 3 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon TRAP-gamma PF07074.12 KPA43315.1 - 3.4 7.2 4.6 5.2 6.6 4.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) LRR_6 PF13516.6 KPA43316.1 - 0.05 13.7 8.1 0.94 9.7 0.0 5.4 6 0 0 6 6 6 0 Leucine Rich repeat LRR_4 PF12799.7 KPA43316.1 - 0.28 11.7 1.1 30 5.2 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) SLATT_fungal PF18142.1 KPA43317.1 - 8.1 6.5 5.8 19 5.3 0.1 3.2 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain PS_Dcarbxylase PF02666.15 KPA43318.1 - 1.2e-54 184.9 0.0 1.9e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KPA43318.1 - 2.4e-37 127.3 0.0 1.1e-18 67.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_5 PF13202.6 KPA43318.1 - 0.0038 16.7 0.0 0.0098 15.4 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KPA43318.1 - 0.0086 16.5 0.7 0.031 14.7 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KPA43318.1 - 0.01 15.3 0.0 0.03 13.8 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KPA43318.1 - 0.11 12.4 0.0 0.62 10.2 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain PGA2 PF07543.12 KPA43318.1 - 2.3 8.2 6.1 0.64 10.0 0.8 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Fungal_trans PF04082.18 KPA43319.1 - 7.6e-15 54.6 0.9 1.3e-14 53.9 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KPA43319.1 - 0.0001 22.8 16.1 0.013 16.3 3.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA43319.1 - 0.00026 21.3 13.3 0.00051 20.4 4.3 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KPA43319.1 - 0.0025 18.0 3.5 0.13 12.5 0.7 3.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF4729 PF15866.5 KPA43319.1 - 0.04 13.2 0.2 1.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4729) zf-C2H2_6 PF13912.6 KPA43319.1 - 0.081 13.0 1.8 0.28 11.2 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger CTP_transf_like PF01467.26 KPA43320.1 - 1.6e-30 106.2 0.0 3.2e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 KPA43320.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Pectate_lyase PF03211.13 KPA43321.1 - 8.8e-81 270.3 6.1 8.8e-81 270.3 6.1 1.4 2 0 0 2 2 2 1 Pectate lyase CBM_1 PF00734.18 KPA43321.1 - 1.5e-08 34.5 4.9 1.5e-08 34.5 4.9 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain MSP1_C PF07462.11 KPA43321.1 - 0.26 9.9 0.8 0.88 8.2 0.7 1.7 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus ERG4_ERG24 PF01222.17 KPA43322.1 - 8.9e-133 443.2 20.7 1e-132 443.0 20.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ATP-synt_C PF00137.21 KPA43323.1 - 8.4e-35 118.9 34.0 7.6e-22 77.4 14.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Syja_N PF02383.18 KPA43324.1 - 9.3e-99 330.8 0.0 1.3e-98 330.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KPA43324.1 - 1.2e-39 134.6 0.0 2.7e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase Vpu PF00558.19 KPA43324.1 - 0.038 13.7 0.7 0.089 12.6 0.7 1.5 1 0 0 1 1 1 0 Vpu protein Methyltransf_34 PF11312.8 KPA43325.1 - 8.5e-111 370.1 0.0 1e-110 369.8 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Transketolase_N PF00456.21 KPA43326.1 - 1.1e-160 534.2 0.1 1.4e-160 533.8 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KPA43326.1 - 4.6e-42 143.7 0.0 7.9e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KPA43326.1 - 1.1e-13 51.2 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KPA43326.1 - 8.6e-05 21.9 0.1 0.00057 19.2 0.1 1.9 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase DUF5308 PF17233.2 KPA43327.1 - 1.2e-55 188.2 4.4 1.5e-55 187.9 4.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5308) MFS_1 PF07690.16 KPA43328.1 - 1.5e-40 139.2 39.3 1.5e-40 139.2 39.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA43328.1 - 4e-11 42.4 6.4 4e-11 42.4 6.4 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KPA43328.1 - 0.12 10.7 4.7 0.083 11.2 1.7 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CDT1_C PF16679.5 KPA43329.1 - 4.6e-23 81.5 0.1 7.6e-22 77.6 0.0 2.6 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain HYLS1_C PF15311.6 KPA43330.1 - 0.043 14.6 0.1 0.051 14.3 0.1 1.1 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus GCP_C_terminal PF04130.13 KPA43331.1 - 1e-100 337.2 0.2 1.6e-100 336.6 0.2 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KPA43331.1 - 2e-84 283.8 0.0 6.9e-84 282.1 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal SAGA-Tad1 PF12767.7 KPA43332.1 - 2.2e-67 227.3 0.0 2.7e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit cNMP_binding PF00027.29 KPA43334.1 - 1.6e-40 137.1 0.0 4.4e-20 71.5 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain BCAS2 PF05700.11 KPA43335.1 - 5.2e-51 173.3 3.8 6.7e-51 172.9 3.8 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) IFP_35_N PF07334.13 KPA43335.1 - 0.64 10.1 3.4 0.26 11.4 0.5 1.9 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus KfrA_N PF11740.8 KPA43335.1 - 1.6 9.5 11.7 1.2 9.8 7.1 2.5 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term ACC_epsilon PF13822.6 KPA43335.1 - 6.2 7.6 11.3 0.11 13.1 3.0 2.5 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit HABP4_PAI-RBP1 PF04774.15 KPA43336.1 - 6.8e-05 23.7 0.5 0.00011 23.0 0.5 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family DUF3760 PF12586.8 KPA43336.1 - 0.17 12.1 0.1 0.17 12.1 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3760) SH2_2 PF14633.6 KPA43337.1 - 4.3e-83 278.0 0.0 1e-82 276.8 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 KPA43337.1 - 2.2e-39 134.4 0.4 7.8e-39 132.7 0.4 2.0 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 KPA43337.1 - 2.4e-30 104.9 0.0 9.1e-30 103.1 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif YqgF PF14639.6 KPA43337.1 - 4.2e-30 104.5 0.0 3.2e-29 101.6 0.0 2.5 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 KPA43337.1 - 8.8e-22 77.5 25.1 8.8e-22 77.5 25.1 6.5 3 1 1 6 6 6 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KPA43337.1 - 6.1e-07 30.2 1.9 2.1e-05 25.3 1.9 3.5 1 1 0 1 1 1 1 HHH domain S1 PF00575.23 KPA43337.1 - 3.7e-06 27.2 0.2 1.2e-05 25.6 0.2 1.8 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 KPA43337.1 - 1.2e-05 25.4 0.0 3.6e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 KPA43337.1 - 0.00013 22.1 0.0 0.0011 19.2 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif Tex_YqgF PF16921.5 KPA43337.1 - 0.005 17.3 0.0 0.016 15.7 0.0 1.9 1 1 0 1 1 1 1 Tex protein YqgF-like domain Pkinase PF00069.25 KPA43338.1 - 7.9e-64 215.6 0.0 1.1e-63 215.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA43338.1 - 1.1e-37 129.7 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPA43338.1 - 7.9e-05 21.6 0.3 0.00035 19.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KPA43338.1 - 8.7e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Med3 PF11593.8 KPA43338.1 - 0.0084 15.4 2.8 0.013 14.8 2.8 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Eisosome1 PF12757.7 KPA43338.1 - 0.02 15.1 0.1 0.042 14.1 0.1 1.5 1 0 0 1 1 1 0 Eisosome protein 1 Haspin_kinase PF12330.8 KPA43338.1 - 0.044 12.7 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Spt20 PF12090.8 KPA43338.1 - 0.67 9.5 5.8 1.3 8.6 5.8 1.4 1 0 0 1 1 1 0 Spt20 family SPX PF03105.19 KPA43338.1 - 4.1 7.2 8.5 6 6.7 8.5 1.2 1 0 0 1 1 1 0 SPX domain HAD_2 PF13419.6 KPA43339.1 - 3e-14 53.5 0.0 2.4e-13 50.6 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA43339.1 - 1.5e-10 41.7 0.0 1.3e-06 28.8 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA43339.1 - 3.4e-07 30.2 0.3 6e-07 29.4 0.3 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KPA43339.1 - 0.0024 18.3 0.0 0.1 13.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KPA43339.1 - 0.017 14.7 0.2 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Methyltransf_32 PF13679.6 KPA43340.1 - 0.05 13.6 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FUSC_2 PF13515.6 KPA43341.1 - 1.6e-22 79.9 8.5 1.6e-22 79.9 8.5 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 KPA43341.1 - 3.7e-06 25.8 9.3 6.9e-06 24.9 1.9 3.1 2 1 0 2 2 2 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 KPA43341.1 - 0.0005 20.0 0.0 0.0014 18.5 0.0 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC-like PF12805.7 KPA43341.1 - 0.15 11.1 3.4 3.3 6.7 0.5 2.5 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS DUF5325 PF17259.2 KPA43341.1 - 3.9 7.4 11.2 0.63 10.0 4.9 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5325) DNA_pol_E_B PF04042.16 KPA43342.1 - 3.9e-62 209.4 0.0 5.5e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.25 KPA43344.1 - 2e-73 247.0 0.0 2.9e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA43344.1 - 1.3e-37 129.5 0.0 3.2e-37 128.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KPA43344.1 - 2.1e-17 63.6 0.2 2.3e-09 37.7 0.0 2.9 2 1 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KPA43344.1 - 2.9e-15 56.1 0.2 5.6e-15 55.2 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KPA43344.1 - 4.9e-06 26.1 0.0 8.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KPA43344.1 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KPA43344.1 - 0.0017 17.4 0.0 0.0048 15.9 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain YukC PF10140.9 KPA43344.1 - 0.0076 15.1 0.1 0.013 14.3 0.1 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KPA43344.1 - 0.09 12.7 0.3 0.41 10.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ICL PF00463.21 KPA43345.1 - 1.6e-295 980.6 0.8 1.8e-295 980.4 0.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KPA43345.1 - 4.4e-11 42.7 0.1 1.5e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.18 KPA43346.1 - 5.1e-190 632.7 0.0 6e-190 632.4 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KPA43346.1 - 3.3e-13 49.1 0.1 5.4e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Yippee-Mis18 PF03226.14 KPA43347.1 - 7.9e-21 74.2 0.0 1.1e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KPA43347.1 - 0.0061 16.8 0.6 0.029 14.6 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of RIG-I zinc_ribbon_12 PF11331.8 KPA43347.1 - 0.015 15.1 0.1 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain Peptidase_M20 PF01546.28 KPA43348.1 - 2.1e-33 115.8 0.1 2.8e-33 115.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPA43348.1 - 1.9e-11 43.9 0.0 3.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KPA43348.1 - 0.18 11.4 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 DWNN PF08783.11 KPA43349.1 - 3e-31 107.5 0.1 5.9e-31 106.6 0.1 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KPA43349.1 - 4.1e-09 36.1 6.8 1.9e-08 33.9 6.2 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KPA43349.1 - 0.0013 18.5 10.0 0.0013 18.5 10.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 KPA43349.1 - 0.0059 16.6 1.1 0.0059 16.6 1.1 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-RING_2 PF13639.6 KPA43349.1 - 0.011 16.1 7.2 0.023 15.0 7.2 1.6 1 0 0 1 1 1 0 Ring finger domain U-box PF04564.15 KPA43349.1 - 0.021 15.0 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 U-box domain zf-DNL PF05180.12 KPA43349.1 - 0.034 14.1 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 DNL zinc finger zf-RING_4 PF14570.6 KPA43349.1 - 0.042 13.6 6.4 0.093 12.5 6.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KPA43349.1 - 0.11 12.4 2.2 0.21 11.5 2.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KPA43349.1 - 0.36 10.8 13.8 0.045 13.7 8.2 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KPA43349.1 - 0.63 10.0 10.4 1.3 9.0 10.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 KPA43349.1 - 0.73 10.1 6.0 0.15 12.3 1.5 2.0 2 1 0 2 2 2 0 FYVE-type zinc finger zf-Nse PF11789.8 KPA43349.1 - 1.3 8.9 8.9 1 9.2 6.3 2.1 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KPA43349.1 - 1.4 9.0 6.7 3.2 7.9 6.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KPA43349.1 - 1.9 8.7 9.5 6.4 7.0 9.5 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING HypA PF01155.19 KPA43349.1 - 2.7 8.0 5.3 4.8 7.2 3.0 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ArsA_ATPase PF02374.15 KPA43350.1 - 9.5e-109 363.3 0.0 1.1e-108 363.1 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 KPA43350.1 - 1.8e-12 47.4 0.0 3e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KPA43350.1 - 2.5e-12 47.0 0.0 9.4e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 KPA43350.1 - 5.1e-06 26.1 0.0 1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 KPA43350.1 - 2.5e-05 23.8 0.1 0.00021 20.8 0.0 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KPA43350.1 - 0.00013 21.5 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 KPA43350.1 - 0.00017 21.3 0.0 0.0016 18.1 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KPA43350.1 - 0.029 14.8 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KPA43350.1 - 0.042 13.0 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KPA43350.1 - 0.066 13.8 0.0 0.35 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KPA43350.1 - 0.071 12.7 0.3 0.12 11.9 0.3 1.6 1 1 0 1 1 1 0 AAA domain Transthyretin PF00576.21 KPA43351.1 - 2.2e-34 118.5 0.0 2.8e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family zf-C3HC4 PF00097.25 KPA43353.1 - 2e-07 30.7 5.2 4e-07 29.8 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA43353.1 - 3.9e-07 30.0 2.6 3.9e-07 30.0 2.6 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KPA43353.1 - 4.7e-07 29.6 4.1 9.2e-07 28.6 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA43353.1 - 2.1e-06 28.0 4.6 4.4e-06 26.9 4.6 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KPA43353.1 - 9.8e-06 25.4 3.8 1.8e-05 24.6 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KPA43353.1 - 1.2e-05 25.0 7.0 6.6e-05 22.7 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPA43353.1 - 7.6e-05 22.8 5.8 0.00042 20.4 5.9 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING DUF3150 PF11348.8 KPA43353.1 - 0.0056 16.0 0.1 0.0085 15.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3150) Prok-RING_4 PF14447.6 KPA43353.1 - 0.0075 16.1 9.3 0.065 13.1 9.1 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Meis_PKNOX_N PF16493.5 KPA43353.1 - 0.032 14.6 0.3 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 Cytochrom_C_2 PF01322.20 KPA43353.1 - 0.033 15.1 1.5 0.062 14.2 0.7 1.8 2 0 0 2 2 1 0 Cytochrome C' zf-rbx1 PF12678.7 KPA43353.1 - 0.11 12.8 2.5 0.27 11.5 2.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain TerY_C PF15616.6 KPA43353.1 - 0.34 11.0 1.5 0.47 10.6 0.3 1.8 2 0 0 2 2 2 0 TerY-C metal binding domain zf-RING_10 PF16685.5 KPA43353.1 - 1.3 9.2 4.7 3 8.0 4.7 1.6 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-MIZ PF02891.20 KPA43353.1 - 1.4 8.7 5.8 4.5 7.1 5.8 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger AMPK1_CBM PF16561.5 KPA43354.1 - 4.1e-23 81.4 0.4 8.4e-23 80.4 0.4 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KPA43354.1 - 0.00036 20.8 0.1 0.00082 19.7 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_114 PF03537.13 KPA43356.1 - 7e-86 287.3 1.5 8.6e-86 287.0 1.5 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Fungal_trans PF04082.18 KPA43357.1 - 6.6e-25 87.6 1.0 1.5e-24 86.5 0.6 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43357.1 - 2.9e-07 30.5 11.6 2.9e-07 30.5 11.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.6 KPA43358.1 - 1.9e-42 145.3 0.0 2.6e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KPA43358.1 - 1.2e-10 41.7 0.0 1.8e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short_C2 PF13561.6 KPA43359.1 - 4.7e-51 173.6 0.0 6.4e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA43359.1 - 1.5e-40 138.8 0.1 2e-40 138.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA43359.1 - 1.5e-10 41.3 0.4 2.1e-10 40.8 0.4 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA43359.1 - 0.026 13.6 0.0 0.04 13.0 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein RuBisCO_large PF00016.20 KPA43359.1 - 0.22 10.7 1.8 0.16 11.1 0.4 1.4 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Hydrolase_6 PF13344.6 KPA43360.1 - 1.3e-21 76.6 0.0 2.4e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA43360.1 - 4.4e-13 49.1 0.0 2.8e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KPA43360.1 - 0.082 13.2 0.0 21 5.3 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Mitochondr_Som1 PF11093.8 KPA43362.1 - 5.6e-27 93.6 0.1 7.1e-27 93.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Ribosomal_L22 PF00237.19 KPA43363.1 - 1.7e-22 79.6 0.0 3.1e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e PKcGMP_CC PF16808.5 KPA43363.1 - 0.88 9.5 5.8 14 5.6 1.6 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CFEM PF05730.11 KPA43364.1 - 0.00074 19.6 9.5 0.0017 18.4 9.5 1.5 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 KPA43364.1 - 0.32 10.4 0.1 0.32 10.4 0.1 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Presenilin PF01080.17 KPA43364.1 - 0.34 9.6 1.9 0.47 9.2 1.9 1.1 1 0 0 1 1 1 0 Presenilin Podoplanin PF05808.11 KPA43364.1 - 0.42 10.7 15.3 1.2 9.2 15.3 1.8 1 1 0 1 1 1 0 Podoplanin PPP4R2 PF09184.11 KPA43364.1 - 1.2 8.6 6.5 1.6 8.3 6.5 1.1 1 0 0 1 1 1 0 PPP4R2 Hamartin PF04388.12 KPA43364.1 - 3.6 6.1 8.4 4.4 5.8 8.4 1.1 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.9 KPA43364.1 - 7.8 4.9 7.8 10 4.5 7.8 1.1 1 0 0 1 1 1 0 Macoilin family RRM_1 PF00076.22 KPA43365.1 - 4.1e-50 167.5 0.2 1.4e-18 66.5 0.2 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPA43365.1 - 2.6e-36 123.3 0.6 5.5e-26 90.2 0.0 4.0 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KPA43365.1 - 7.8e-14 51.4 0.1 0.0014 18.6 0.0 3.8 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KPA43365.1 - 1.4e-10 40.9 0.0 8.8e-07 28.6 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KPA43365.1 - 2.6e-07 30.6 0.0 0.099 12.6 0.0 3.6 2 1 1 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KPA43365.1 - 1.9e-05 24.6 0.2 1.1 9.4 0.1 4.0 4 0 0 4 4 4 2 RNA binding motif RRM_7 PF16367.5 KPA43365.1 - 0.00026 21.0 0.0 0.25 11.5 0.0 3.7 4 0 0 4 4 4 1 RNA recognition motif Lsm_interact PF05391.11 KPA43365.1 - 0.005 16.3 0.7 0.012 15.0 0.7 1.7 1 0 0 1 1 1 1 Lsm interaction motif TPR_14 PF13428.6 KPA43365.1 - 0.0074 17.0 0.0 1.3 10.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat BRAP2 PF07576.12 KPA43365.1 - 0.018 15.3 0.1 0.36 11.1 0.0 2.4 2 0 0 2 2 2 0 BRCA1-associated protein 2 RL PF17797.1 KPA43365.1 - 0.027 14.4 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 RL domain PHM7_cyt PF14703.6 KPA43365.1 - 0.035 14.4 5.6 12 6.1 0.1 4.4 4 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Helicase_C PF00271.31 KPA43366.1 - 5.2e-14 52.5 0.0 1.5e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KPA43366.1 - 1.2e-13 51.3 1.0 2.3e-13 50.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 KPA43366.1 - 2.4e-11 43.7 0.0 5.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KPA43366.1 - 1.4e-08 35.0 0.0 2.9e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KPA43366.1 - 2.5e-08 34.3 0.1 9.4e-08 32.4 0.1 2.0 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KPA43366.1 - 0.02 14.3 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 KPA43366.1 - 0.041 14.4 4.1 0.45 11.0 2.4 3.3 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KPA43366.1 - 0.085 12.8 0.0 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 KPA43366.1 - 0.18 12.3 0.3 1 9.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Gcn1_N PF12074.8 KPA43367.1 - 1.8e-117 392.7 6.1 8.1e-117 390.5 6.1 2.3 1 0 0 1 1 1 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KPA43367.1 - 6.6e-29 97.5 37.8 0.017 15.3 0.0 21.6 24 0 0 24 24 21 6 HEAT repeat HEAT_EZ PF13513.6 KPA43367.1 - 2.1e-28 98.4 52.3 5.5e-07 30.0 0.0 20.2 18 4 7 25 25 23 6 HEAT-like repeat HEAT_2 PF13646.6 KPA43367.1 - 6.7e-24 84.1 52.1 0.00035 20.9 0.2 15.0 10 4 7 17 17 16 7 HEAT repeats CLASP_N PF12348.8 KPA43367.1 - 8.4e-15 55.0 0.0 0.014 15.0 0.0 6.9 5 1 2 7 7 7 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 KPA43367.1 - 3.1e-13 50.1 0.0 8.8 7.0 0.0 9.5 6 1 2 8 8 8 0 Vacuolar 14 Fab1-binding region ParcG PF10274.9 KPA43367.1 - 4.4e-12 46.5 4.0 4.9e-05 23.5 0.0 6.8 6 2 1 7 7 6 3 Parkin co-regulated protein Cnd1 PF12717.7 KPA43367.1 - 8.2e-12 45.5 11.3 0.32 11.0 0.2 10.5 5 3 5 11 11 11 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KPA43367.1 - 2.2e-10 39.7 10.1 1.7e-05 23.6 0.6 6.4 5 3 1 6 6 6 4 Adaptin N terminal region DUF937 PF06078.11 KPA43367.1 - 3.9e-06 27.5 0.8 2.8 8.5 0.0 6.5 5 1 1 6 6 6 2 Bacterial protein of unknown function (DUF937) TIP120 PF08623.10 KPA43367.1 - 5e-05 23.1 0.1 1.1 9.0 0.0 6.1 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) Tti2 PF10521.9 KPA43367.1 - 0.00015 21.4 0.8 1.4 8.4 0.0 6.3 8 0 0 8 8 8 1 Tti2 family DUF3385 PF11865.8 KPA43367.1 - 0.00072 19.5 2.1 3.6 7.5 0.0 6.5 6 2 1 7 7 6 1 Domain of unknown function (DUF3385) FANCI_S2 PF14676.6 KPA43367.1 - 0.0015 18.8 1.0 0.35 11.2 0.0 4.7 4 1 0 4 4 4 1 FANCI solenoid 2 MMS19_C PF12460.8 KPA43367.1 - 0.0059 15.8 20.2 0.059 12.5 0.1 7.7 6 2 2 8 8 8 2 RNAPII transcription regulator C-terminal TFCD_C PF12612.8 KPA43367.1 - 0.012 15.4 7.7 0.024 14.5 0.2 4.3 4 1 0 4 4 4 0 Tubulin folding cofactor D C terminal Ipi1_N PF12333.8 KPA43367.1 - 0.014 16.0 2.1 0.63 10.7 0.0 4.6 5 0 0 5 5 4 0 Rix1 complex component involved in 60S ribosome maturation RIX1 PF08167.12 KPA43367.1 - 0.081 12.7 4.9 0.22 11.3 0.3 4.1 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis Arm PF00514.23 KPA43367.1 - 0.52 10.4 18.5 46 4.2 0.0 10.3 12 0 0 12 12 11 0 Armadillo/beta-catenin-like repeat ADSL_C PF10397.9 KPA43367.1 - 1.4 9.5 3.6 15 6.2 0.0 4.2 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminus WASH-7_C PF14746.6 KPA43367.1 - 1.9 8.2 4.7 2.8 7.6 1.2 2.7 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal HEAT_PBS PF03130.16 KPA43367.1 - 4.1 8.4 18.9 69 4.6 0.6 9.1 9 0 0 9 9 7 0 PBS lyase HEAT-like repeat Ribosomal_L19e PF01280.20 KPA43368.1 - 5.1e-61 205.0 8.5 5.1e-61 205.0 8.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e TRAP-gamma PF07074.12 KPA43368.1 - 1.9 8.0 5.9 2.9 7.4 5.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) SHMT PF00464.19 KPA43369.1 - 5.9e-197 654.1 0.0 6.9e-197 653.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 KPA43369.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family 2OG-FeII_Oxy_2 PF13532.6 KPA43370.1 - 1.7e-29 103.4 0.1 4.2e-29 102.1 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KPA43370.1 - 1e-24 87.6 0.0 2.1e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family GST_C_3 PF14497.6 KPA43370.1 - 0.0055 16.9 0.0 0.032 14.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA43370.1 - 0.014 15.6 0.1 0.038 14.2 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPA43370.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TAF8_C PF10406.9 KPA43371.1 - 4.8e-18 65.5 0.2 1.2e-17 64.2 0.2 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KPA43371.1 - 1.9e-10 40.6 0.3 1.1e-09 38.2 0.0 2.2 3 0 0 3 3 3 1 Bromodomain associated WD40 PF00400.32 KPA43372.1 - 1.9e-43 145.6 22.0 1.1e-08 35.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA43372.1 - 1.4e-08 34.9 0.5 0.13 12.5 0.0 4.5 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA43372.1 - 1.3e-05 24.1 8.5 0.049 12.3 0.1 4.4 2 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KPA43372.1 - 0.0054 15.7 0.1 9.3 5.1 0.0 3.9 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KPA43372.1 - 0.016 15.1 0.5 22 5.1 0.0 4.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KPA43372.1 - 0.018 14.4 0.0 0.55 9.5 0.0 2.3 2 1 1 3 3 3 0 WD40-like domain OST3_OST6 PF04756.13 KPA43373.1 - 5.2e-106 354.3 0.0 6.3e-106 354.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 KPA43373.1 - 0.042 14.7 0.3 0.042 14.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Castor1_N PF18700.1 KPA43373.1 - 0.069 13.0 0.0 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain DUF3169 PF11368.8 KPA43373.1 - 0.76 9.2 5.2 0.43 10.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) MscS_porin PF12795.7 KPA43374.1 - 0.0069 16.0 12.7 0.0069 16.0 12.7 3.7 2 1 2 4 4 4 1 Mechanosensitive ion channel porin domain Leu_zip PF15294.6 KPA43374.1 - 0.0082 15.7 21.3 0.0082 15.7 21.3 2.9 2 1 1 3 3 3 1 Leucine zipper Spc7 PF08317.11 KPA43374.1 - 0.025 13.5 47.8 1.1 8.1 27.6 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 KPA43374.1 - 0.027 13.1 33.2 0.01 14.5 28.6 2.0 1 1 1 2 2 2 0 AAA domain FPP PF05911.11 KPA43374.1 - 0.049 11.8 43.0 0.27 9.4 7.3 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4268 PF14088.6 KPA43374.1 - 0.17 11.8 5.1 0.34 10.8 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) TPR_MLP1_2 PF07926.12 KPA43374.1 - 0.28 11.2 48.8 0.22 11.6 5.5 4.1 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 KPA43374.1 - 0.45 10.6 29.1 2.7 8.1 3.5 3.9 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 GAS PF13851.6 KPA43374.1 - 1.2 8.4 55.0 0.52 9.6 18.4 4.3 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding IFT57 PF10498.9 KPA43374.1 - 1.6 7.6 36.9 1.9 7.4 16.9 2.6 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 KPA43374.1 - 1.8 8.0 48.0 1.3 8.4 18.0 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 EzrA PF06160.12 KPA43374.1 - 3 5.9 34.4 5.5 5.0 34.4 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Tropomyosin_1 PF12718.7 KPA43374.1 - 3.8 7.7 46.9 54 3.9 15.4 3.3 1 1 1 2 2 2 0 Tropomyosin like DUF4201 PF13870.6 KPA43374.1 - 5.6 6.7 49.2 3.5 7.3 13.9 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) DUF3584 PF12128.8 KPA43374.1 - 6.3 4.2 40.7 13 3.1 40.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 KPA43374.1 - 9.2 6.3 26.6 1.3 9.0 1.3 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Ribosomal_L18 PF17135.4 KPA43375.1 - 8.8e-93 308.9 2.3 9.8e-93 308.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KPA43375.1 - 0.0033 18.1 0.4 0.0033 18.1 0.4 2.2 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Mito_carr PF00153.27 KPA43376.1 - 1.7e-74 245.8 2.5 3.8e-24 84.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPA43376.1 - 5.9e-05 22.4 0.2 0.0044 16.2 0.0 3.0 3 1 1 4 4 4 2 Gammaproteobacterial serine protease RRM_1 PF00076.22 KPA43377.1 - 7.2e-12 45.0 0.0 9.9e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPA43377.1 - 0.00013 21.9 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CH PF00307.31 KPA43379.1 - 2.3e-70 233.7 0.0 8e-18 64.6 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KPA43379.1 - 5.5e-06 26.7 0.6 7.2e-05 23.2 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KPA43379.1 - 0.0042 16.5 0.2 4.7 7.0 0.1 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KPA43379.1 - 0.017 15.0 0.3 0.98 9.5 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain zf-RING_2 PF13639.6 KPA43380.1 - 0.027 14.8 2.6 0.027 14.8 2.6 2.1 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 KPA43380.1 - 7.4 6.8 7.9 0.83 9.9 3.4 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DDHD PF02862.17 KPA43381.1 - 1.5e-64 218.2 0.1 1.5e-64 218.2 0.1 3.6 3 2 0 3 3 3 1 DDHD domain AAR2 PF05282.11 KPA43381.1 - 0.014 14.8 0.2 0.014 14.8 0.2 2.0 2 0 0 2 2 2 0 AAR2 protein Hydrolase_4 PF12146.8 KPA43381.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KPA43381.1 - 0.2 11.2 0.0 1.6 8.3 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase RNA_pol_Rpb1_1 PF04997.12 KPA43382.1 - 1.7e-84 283.8 0.1 2.6e-84 283.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KPA43382.1 - 3.1e-76 256.3 0.3 4.5e-76 255.8 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KPA43382.1 - 3.6e-72 242.0 0.0 6.4e-72 241.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KPA43382.1 - 1e-38 132.8 0.0 2.2e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KPA43382.1 - 1.7e-27 95.5 0.1 4.2e-27 94.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-ribbon_3 PF13248.6 KPA43382.1 - 3.5 7.2 5.1 5.2 6.6 0.4 2.8 3 0 0 3 3 3 0 zinc-ribbon domain SRAP PF02586.14 KPA43383.1 - 1e-74 250.8 0.0 1.1e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) PH PF00169.29 KPA43384.1 - 2e-06 28.2 0.2 9.7e-06 26.0 0.0 2.3 3 0 0 3 3 3 1 PH domain Prominin PF05478.11 KPA43384.1 - 0.13 10.2 0.2 0.19 9.6 0.2 1.2 1 0 0 1 1 1 0 Prominin Gar1 PF04410.14 KPA43385.1 - 3.3e-38 130.9 0.0 4.4e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region MFS_1 PF07690.16 KPA43386.1 - 6e-30 104.4 51.2 6e-30 104.4 51.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CDP-OH_P_transf PF01066.21 KPA43387.1 - 2.4e-14 53.8 1.3 3.6e-14 53.3 0.4 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.8 KPA43388.1 - 4e-169 562.8 0.0 5.8e-169 562.2 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KPA43388.1 - 1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.6 KPA43388.1 - 0.031 14.4 1.4 0.044 13.9 0.5 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12 Whi5 PF08528.11 KPA43389.1 - 9.3e-10 37.9 0.1 1.6e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Whi5 like Peptidase_C14 PF00656.22 KPA43392.1 - 3.3e-63 213.9 0.0 4.4e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KPA43392.1 - 0.17 11.8 0.8 0.5 10.3 0.0 2.2 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Cnn_1N PF07989.11 KPA43393.1 - 1.9e-26 92.0 4.2 1.9e-26 92.0 4.2 16.4 5 4 9 14 14 14 1 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KPA43393.1 - 1.9e-22 79.6 0.6 1.9e-22 79.6 0.6 5.7 6 2 0 6 6 6 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Filament PF00038.21 KPA43393.1 - 4.3e-06 26.5 47.4 4.3e-06 26.5 47.4 9.6 1 1 6 9 9 9 5 Intermediate filament protein DUF3584 PF12128.8 KPA43393.1 - 7.2e-06 23.9 45.9 7.2e-06 23.9 45.9 5.7 1 1 3 4 4 4 1 Protein of unknown function (DUF3584) MscS_porin PF12795.7 KPA43393.1 - 0.00045 19.8 29.2 0.00045 19.8 29.2 9.2 1 1 7 8 8 8 3 Mechanosensitive ion channel porin domain BRE1 PF08647.11 KPA43393.1 - 0.0024 17.9 5.7 0.0024 17.9 5.7 14.0 4 1 10 15 15 15 7 BRE1 E3 ubiquitin ligase GAS PF13851.6 KPA43393.1 - 0.003 16.9 32.0 0.003 16.9 32.0 11.4 1 1 8 10 10 10 6 Growth-arrest specific micro-tubule binding Synaptobrevin PF00957.21 KPA43393.1 - 0.005 16.6 5.7 0.005 16.6 5.7 7.4 8 2 1 9 9 9 1 Synaptobrevin HALZ PF02183.18 KPA43393.1 - 0.011 16.0 1.7 0.011 16.0 1.7 12.1 13 1 1 14 14 14 0 Homeobox associated leucine zipper Halo_GVPC PF05465.13 KPA43393.1 - 0.9 9.9 7.3 18 5.7 0.2 4.6 4 0 0 4 4 4 0 Halobacterial gas vesicle protein C (GVPC) repeat Transglut_core2 PF13369.6 KPA43394.1 - 3.2e-24 85.2 0.0 6.3e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 KPA43394.1 - 8.8e-13 48.6 0.0 2.7e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.7 KPA43394.1 - 7.4e-05 22.6 1.3 0.00022 21.1 0.7 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KPA43394.1 - 0.00086 19.1 0.3 0.0024 17.7 0.3 1.9 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KPA43394.1 - 0.079 13.5 0.3 0.16 12.5 0.3 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Peptidase_C12 PF01088.21 KPA43395.1 - 1.5e-61 207.8 0.0 2.3e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 I-set PF07679.16 KPA43396.1 - 0.0029 17.7 0.0 1.8 8.7 0.1 4.6 5 0 0 5 5 5 1 Immunoglobulin I-set domain DUF1918 PF08940.11 KPA43396.1 - 0.025 14.2 0.7 23 4.7 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1918) HSF_DNA-bind PF00447.17 KPA43397.1 - 1.3e-30 105.8 0.5 3.2e-30 104.6 0.5 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KPA43397.1 - 2.6e-23 82.3 0.1 1.5e-22 79.9 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain PCRF PF03462.18 KPA43397.1 - 0.0008 19.3 0.9 1.5 8.7 0.0 2.3 2 0 0 2 2 2 2 PCRF domain Ets PF00178.22 KPA43397.1 - 0.17 12.4 0.1 0.72 10.4 0.0 1.9 2 0 0 2 2 2 0 Ets-domain YabA PF06156.13 KPA43397.1 - 0.22 12.2 5.1 0.46 11.1 5.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA CortBP2 PF09727.9 KPA43397.1 - 0.31 10.9 5.6 0.56 10.1 5.6 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 CENP-H PF05837.12 KPA43397.1 - 0.4 11.1 4.6 0.76 10.2 4.6 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) W2 PF02020.18 KPA43398.1 - 4.9e-19 68.3 2.0 1e-18 67.2 2.0 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KPA43398.1 - 1.2e-10 40.7 9.7 7e-06 25.6 5.2 3.2 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KPA43398.1 - 8.3e-06 25.5 11.8 0.00029 20.5 5.2 3.3 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KPA43398.1 - 0.00053 18.3 2.6 0.001 17.3 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 KPA43398.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 KPA43398.1 - 0.0045 16.0 2.4 0.089 11.7 2.4 2.1 1 1 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 KPA43398.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain CP2 PF04516.15 KPA43399.1 - 6.3e-84 280.9 0.0 9.5e-84 280.3 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 KPA43399.1 - 0.03 13.1 0.0 0.058 12.2 0.0 1.4 1 0 0 1 1 1 0 Tektin family TMF_DNA_bd PF12329.8 KPA43399.1 - 0.14 12.2 0.3 0.35 10.9 0.3 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF167 PF02594.16 KPA43400.1 - 2.7e-22 78.7 0.3 4.9e-22 77.8 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 HAD_SAK_1 PF10307.9 KPA43401.1 - 1.1e-80 270.3 0.0 1.7e-80 269.6 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins API5 PF05918.11 KPA43401.1 - 9.4 4.9 6.5 14 4.4 6.5 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MFS_1 PF07690.16 KPA43402.1 - 8.8e-36 123.5 36.0 1.7e-35 122.6 33.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA43402.1 - 1.1e-07 31.1 5.2 1.1e-07 31.1 5.2 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter eIF2A PF08662.11 KPA43403.1 - 1.9e-79 266.1 0.0 7e-79 264.2 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KPA43403.1 - 0.0037 18.1 0.4 5 8.2 0.0 4.3 3 1 1 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.12 KPA43403.1 - 0.12 12.3 4.2 42 4.2 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RPAP1_C PF08620.10 KPA43404.1 - 4.8e-28 97.1 0.0 8.1e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KPA43404.1 - 1.1e-20 73.2 4.7 2e-20 72.3 4.7 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF438 PF04282.13 KPA43404.1 - 0.06 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF438) Enterotoxin_a PF01375.17 KPA43404.1 - 0.22 11.1 0.5 0.35 10.4 0.5 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain HUN PF08729.10 KPA43405.1 - 6.2e-08 32.5 0.1 1.3e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain VHS PF00790.19 KPA43406.1 - 1.2e-44 151.5 0.0 6.2e-44 149.3 0.0 2.1 3 0 0 3 3 3 1 VHS domain Alpha_adaptinC2 PF02883.20 KPA43406.1 - 1e-21 77.3 0.5 2.6e-21 76.0 0.5 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 KPA43406.1 - 1.4e-19 70.1 0.3 1.4e-19 70.1 0.3 2.1 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KPA43406.1 - 3.6e-08 32.9 0.0 1.3e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 GGA N-GAT domain Clathrin_H_link PF13838.6 KPA43406.1 - 0.096 12.6 0.1 3.2 7.7 0.0 2.6 2 0 0 2 2 2 0 Clathrin-H-link Ribo_biogen_C PF04034.13 KPA43407.1 - 5.9e-51 171.5 0.0 8.3e-51 171.0 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KPA43407.1 - 1e-10 41.3 1.1 1e-10 41.3 1.1 1.6 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI BUD22 PF09073.10 KPA43407.1 - 0.53 9.6 23.3 0.75 9.1 23.3 1.2 1 0 0 1 1 1 0 BUD22 GTP_EFTU PF00009.27 KPA43408.1 - 2.9e-34 118.3 4.3 8.8e-33 113.5 4.3 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KPA43408.1 - 5.8e-28 97.1 0.8 2.3e-27 95.2 0.8 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KPA43408.1 - 1.2e-09 38.3 0.1 3.2e-09 36.9 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA43408.1 - 4.8e-06 26.6 1.0 0.00012 22.0 0.1 2.4 1 1 1 2 2 2 1 RsgA GTPase IF2_N PF04760.15 KPA43408.1 - 6e-06 26.0 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.21 KPA43408.1 - 1.7e-05 24.3 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 KPA43408.1 - 3.9e-05 23.2 0.2 8e-05 22.2 0.2 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KPA43408.1 - 0.00093 18.7 0.1 0.0024 17.4 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KPA43408.1 - 0.0011 18.7 0.2 0.0033 17.2 0.2 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 KPA43408.1 - 0.0044 16.6 0.1 0.0085 15.7 0.1 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA43408.1 - 0.0044 17.2 0.0 0.0085 16.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D2 PF03144.25 KPA43408.1 - 0.007 16.7 4.7 2.2 8.7 0.1 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 DUF3854 PF12965.7 KPA43408.1 - 0.05 13.6 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) ATP_bind_1 PF03029.17 KPA43408.1 - 0.06 13.1 0.0 0.24 11.2 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 KPA43408.1 - 0.07 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MeaB PF03308.16 KPA43408.1 - 0.37 9.7 7.7 0.2 10.6 1.8 3.2 2 2 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KPA43408.1 - 6.4 6.8 6.7 27 4.8 0.0 3.7 3 1 1 4 4 4 0 Dynamin family GPP34 PF05719.11 KPA43410.1 - 3.7e-69 232.9 0.5 4.6e-69 232.5 0.5 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SURF6 PF04935.12 KPA43411.1 - 9e-48 162.7 37.3 9e-48 162.7 37.3 5.1 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 KPA43411.1 - 1.4e-14 54.4 0.1 1.4e-14 54.4 0.1 8.7 5 2 1 6 6 6 1 60S ribosome biogenesis protein Rrp14 PP28 PF10252.9 KPA43412.1 - 3.7e-22 78.6 13.3 3.7e-22 78.6 13.3 3.3 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 CoA_trans PF01144.23 KPA43414.1 - 3.4e-99 330.6 0.4 9.1e-60 201.7 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Glyoxalase PF00903.25 KPA43415.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3659 PF12396.8 KPA43415.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Nrap_D5 PF17406.2 KPA43416.1 - 7.3e-62 207.9 0.4 2.2e-60 203.1 0.1 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 KPA43416.1 - 6.2e-59 198.9 0.0 1.1e-58 198.1 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 KPA43416.1 - 1.1e-49 168.1 0.3 6.4e-46 155.9 0.0 2.6 2 1 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 KPA43416.1 - 7.6e-46 155.9 1.1 7.6e-46 155.9 1.1 1.8 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D3 PF17404.2 KPA43416.1 - 4.6e-41 140.6 0.0 1.1e-40 139.3 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KPA43416.1 - 6.6e-38 130.0 0.0 1.8e-37 128.6 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 Xin PF08043.12 KPA43416.1 - 0.19 11.4 0.4 0.4 10.4 0.4 1.6 1 0 0 1 1 1 0 Xin repeat DNA_primase_S PF01896.19 KPA43417.1 - 1.1e-64 217.7 0.1 1.8e-64 217.0 0.1 1.3 1 0 0 1 1 1 1 DNA primase small subunit DUF2604 PF10790.9 KPA43417.1 - 4.7 7.6 5.2 20 5.6 0.2 3.3 4 0 0 4 4 4 0 Protein of Unknown function (DUF2604) tRNA_m1G_MT PF01746.21 KPA43418.1 - 8.8e-28 97.3 0.0 3e-21 76.0 0.0 2.4 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Tim17 PF02466.19 KPA43419.1 - 0.0065 16.8 6.6 0.013 15.9 5.5 1.8 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family MFS_1 PF07690.16 KPA43420.1 - 1.4e-29 103.2 80.7 7.5e-25 87.6 54.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily AIM24 PF01987.17 KPA43421.1 - 9.3e-51 172.5 0.0 1.2e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Kinesin PF00225.23 KPA43422.1 - 3.6e-84 282.5 0.0 4.8e-84 282.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPA43422.1 - 2.7e-23 82.6 0.0 5.1e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding TPR_14 PF13428.6 KPA43422.1 - 0.032 15.1 0.2 0.12 13.3 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_S8 PF00082.22 KPA43424.1 - 3.1e-42 144.9 0.5 4e-42 144.5 0.5 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KPA43424.1 - 0.0014 19.3 0.0 0.003 18.2 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 KPA43424.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain Penicillinase_R PF03965.16 KPA43424.1 - 0.18 12.1 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor Zip PF02535.22 KPA43425.1 - 2.4e-31 109.2 49.0 3.6e-14 52.7 7.3 4.2 3 1 1 4 4 4 3 ZIP Zinc transporter MutS_V PF00488.21 KPA43426.1 - 2.6e-82 275.4 0.3 4e-82 274.8 0.3 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KPA43426.1 - 4.6e-37 128.1 1.4 1.2e-36 126.8 0.5 2.2 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 KPA43426.1 - 1.1e-21 77.6 0.1 7.4e-19 68.4 0.0 3.0 2 0 0 2 2 2 2 MutS domain II MutS_I PF01624.20 KPA43426.1 - 2.1e-18 66.6 0.0 1.6e-17 63.7 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 KPA43426.1 - 1.2e-13 51.2 3.6 1.9e-13 50.6 1.6 2.5 2 0 0 2 2 2 1 MutS family domain IV Clusterin PF01093.17 KPA43426.1 - 0.032 13.3 0.7 0.066 12.3 0.7 1.5 1 0 0 1 1 1 0 Clusterin HMGL-like PF00682.19 KPA43426.1 - 0.051 13.1 0.1 0.53 9.8 0.2 2.2 2 0 0 2 2 2 0 HMGL-like Acetyltransf_10 PF13673.7 KPA43427.1 - 1e-12 48.1 0.1 6.4e-11 42.3 0.1 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA43427.1 - 7.9e-11 42.2 0.0 1.3e-10 41.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA43427.1 - 6e-09 36.2 0.4 1.5e-08 34.9 0.4 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA43427.1 - 4.2e-07 30.1 0.0 0.0056 16.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA43427.1 - 0.00023 21.2 0.0 0.00045 20.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KPA43427.1 - 0.0055 17.4 0.6 0.13 12.9 0.2 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KPA43427.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Fungal_lectin PF07938.12 KPA43427.1 - 0.064 12.6 0.1 0.077 12.4 0.1 1.2 1 0 0 1 1 1 0 Fungal fucose-specific lectin XFP_C PF09363.10 KPA43428.1 - 5.6e-80 267.6 0.0 7.9e-80 267.1 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KPA43428.1 - 7e-80 266.9 0.0 1.3e-79 266.1 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_N PF09364.10 KPA43428.1 - 2.8e-46 158.0 0.1 4e-46 157.5 0.1 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_N PF09364.10 KPA43429.1 - 3.7e-113 378.0 0.2 4.2e-113 377.9 0.2 1.0 1 0 0 1 1 1 1 XFP N-terminal domain Ank_4 PF13637.6 KPA43430.1 - 8.6e-11 42.1 0.2 4.4e-06 27.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA43430.1 - 2.1e-10 41.0 0.0 3.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA43430.1 - 2.4e-10 40.4 0.1 9.7e-10 38.5 0.1 2.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KPA43430.1 - 4.5e-09 36.3 0.1 1e-06 28.9 0.4 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KPA43430.1 - 6.1e-08 32.3 0.0 2.5e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Pkinase PF00069.25 KPA43432.1 - 7.9e-62 209.0 0.0 1.2e-61 208.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA43432.1 - 4e-48 164.0 0.0 6.3e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA43432.1 - 5.4e-08 32.5 0.0 3.3e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KPA43432.1 - 0.0047 16.3 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KPA43432.1 - 0.01 14.7 0.0 0.027 13.3 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KPA43432.1 - 0.086 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pyridox_oxase_2 PF12766.7 KPA43433.1 - 1.5e-23 83.3 0.0 2.3e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Fungal_trans PF04082.18 KPA43434.1 - 2.8e-26 92.1 0.9 4.1e-26 91.6 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43434.1 - 7.7e-08 32.3 9.9 1.4e-07 31.5 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HemY_N PF07219.13 KPA43435.1 - 0.031 14.5 0.6 0.065 13.4 0.6 1.4 1 0 0 1 1 1 0 HemY protein N-terminus TatD_DNase PF01026.21 KPA43436.1 - 6.3e-25 88.0 0.0 9.8e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Spc24 PF08286.11 KPA43438.1 - 1.6e-36 124.7 1.3 2.2e-35 121.0 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 TEX15 PF15326.6 KPA43438.1 - 0.071 12.8 0.8 0.096 12.4 0.8 1.1 1 0 0 1 1 1 0 Testis expressed sequence 15 DUF3073 PF11273.8 KPA43438.1 - 0.69 10.7 4.3 1.1 10.0 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3073) Septin PF00735.18 KPA43439.1 - 4.9e-119 396.8 0.1 4.9e-119 396.8 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KPA43439.1 - 2e-08 34.3 1.0 4.3e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPA43439.1 - 1.6e-06 27.8 0.5 0.00027 20.5 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KPA43439.1 - 0.00038 21.0 4.1 0.02 15.4 0.0 2.6 2 1 1 3 3 3 1 ABC transporter AIG1 PF04548.16 KPA43439.1 - 0.0012 18.2 1.9 0.0022 17.4 0.0 2.2 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KPA43439.1 - 0.0013 18.7 9.0 0.0021 18.0 0.8 3.4 3 1 0 3 3 2 1 RsgA GTPase Roc PF08477.13 KPA43439.1 - 0.0013 18.9 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KPA43439.1 - 0.0018 18.7 0.1 0.005 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 KPA43439.1 - 0.0052 16.4 0.3 0.039 13.5 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.6 KPA43439.1 - 0.0054 17.0 1.2 0.022 15.0 0.0 2.6 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPA43439.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KPA43439.1 - 0.016 15.3 6.8 0.81 9.7 0.0 4.0 4 1 0 4 4 3 0 Dynamin family RNA_helicase PF00910.22 KPA43439.1 - 0.04 14.3 0.8 0.56 10.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KPA43439.1 - 0.046 13.1 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KPA43439.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KPA43439.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KPA43439.1 - 0.099 12.4 1.9 6.5 6.5 0.0 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 KPA43439.1 - 0.25 10.9 6.4 0.39 10.3 6.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3987 PF13148.6 KPA43439.1 - 1.7 7.5 0.0 1.7 7.5 0.0 2.3 2 0 0 2 2 1 0 Protein of unknown function (DUF3987) Strep_SA_rep PF06696.11 KPA43439.1 - 6.8 6.8 7.3 1.7 8.7 3.1 2.1 1 1 1 2 2 2 0 Streptococcal surface antigen repeat DUF87 PF01935.17 KPA43439.1 - 9.3 6.3 7.9 4.3 7.4 0.0 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain Ferrochelatase PF00762.19 KPA43440.1 - 8.7e-100 333.9 0.0 1.1e-99 333.6 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase MP PF01107.18 KPA43440.1 - 0.042 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) Ku PF02735.16 KPA43441.1 - 4.6e-46 157.1 0.0 1.1e-45 155.8 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KPA43441.1 - 2.2e-37 128.9 0.0 3.1e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KPA43441.1 - 1.1e-28 99.7 0.7 3.1e-28 98.3 0.7 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KPA43441.1 - 4.3e-09 35.9 0.0 8.2e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain DARPP-32 PF05395.12 KPA43441.1 - 2.5 8.3 6.8 0.28 11.4 1.2 2.1 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 Nop14 PF04147.12 KPA43442.1 - 0.00029 19.2 29.0 0.00029 19.2 29.0 2.2 2 0 0 2 2 2 1 Nop14-like family MFS_1 PF07690.16 KPA43443.1 - 1.1e-29 103.5 37.0 1.1e-29 103.5 37.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily PPR_2 PF13041.6 KPA43444.1 - 3.2e-06 27.2 0.0 1.6 9.0 0.0 4.8 5 0 0 5 5 5 3 PPR repeat family PPR PF01535.20 KPA43444.1 - 0.025 14.8 1.7 13 6.3 0.0 5.1 5 0 0 5 5 5 0 PPR repeat LSM PF01423.22 KPA43445.1 - 1.9e-17 62.7 0.0 2.6e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KPA43445.1 - 0.004 17.2 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain FAS_I_H PF18314.1 KPA43446.1 - 4.6e-77 258.2 0.0 1.3e-76 256.7 0.0 1.9 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KPA43446.1 - 5.4e-75 251.2 0.0 1.4e-74 249.8 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KPA43446.1 - 4.1e-22 79.0 0.0 8.1e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KPA43446.1 - 4.3e-18 65.5 0.1 1.9e-17 63.4 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KPA43446.1 - 1.1e-12 48.0 0.0 3.4e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KPA43446.1 - 5.7e-07 29.2 0.0 1.5e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA43446.1 - 0.00011 22.2 0.0 0.0004 20.3 0.0 2.0 1 0 0 1 1 1 1 KR domain End3 PF12761.7 KPA43446.1 - 0.23 11.6 4.9 9.1 6.4 0.4 2.8 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF1729 PF08354.10 KPA43447.1 - 1e-155 518.0 0.0 1.7e-155 517.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KPA43447.1 - 7.2e-91 305.0 0.0 4.9e-89 299.0 0.0 3.3 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KPA43447.1 - 7.8e-53 178.2 0.0 1.7e-52 177.2 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 KPA43447.1 - 9.9e-38 128.5 0.0 2.6e-37 127.1 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 KPA43447.1 - 5.3e-36 124.5 0.0 1.8e-35 122.8 0.0 1.9 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 KPA43447.1 - 8.7e-36 122.8 0.0 1.9e-35 121.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 KPA43447.1 - 2.5e-26 92.3 0.0 7.8e-26 90.8 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase PRCC PF10253.9 KPA43448.1 - 0.0055 17.5 0.4 0.0055 17.5 0.4 6.2 2 2 0 4 4 4 1 Mitotic checkpoint regulator, MAD2B-interacting Fungal_trans PF04082.18 KPA43449.1 - 9e-29 100.3 0.0 1.7e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43449.1 - 0.00018 21.6 9.7 0.00021 21.4 8.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA43450.1 - 1.3e-41 142.4 0.0 2.6e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43450.1 - 2.6e-07 30.7 6.9 6.1e-07 29.5 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KPA43450.1 - 0.66 10.1 11.3 0.65 10.1 0.2 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 S4 PF01479.25 KPA43451.1 - 6.7e-15 54.5 0.1 2.3e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 S4 domain DUF2316 PF10078.9 KPA43451.1 - 0.077 13.2 0.5 2.1 8.6 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) S4_2 PF13275.6 KPA43451.1 - 0.086 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 S4 domain AAA PF00004.29 KPA43452.1 - 1.3e-10 41.8 0.0 2.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA43452.1 - 2.2e-05 24.8 0.0 6.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KPA43452.1 - 3e-05 24.0 0.0 6.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KPA43452.1 - 8e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KPA43452.1 - 9.9e-05 22.3 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 KPA43452.1 - 0.0015 18.7 0.0 0.0049 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA43452.1 - 0.0021 18.5 0.0 0.0079 16.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KPA43452.1 - 0.0023 17.7 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KPA43452.1 - 0.0028 17.7 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KPA43452.1 - 0.022 15.3 0.0 0.058 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KPA43452.1 - 0.03 14.2 0.0 0.092 12.7 0.0 1.8 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 KPA43452.1 - 0.047 13.7 0.2 0.34 10.9 0.0 2.4 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KPA43452.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 KPA43452.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 KPA43452.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain FMN_dh PF01070.18 KPA43453.1 - 1.9e-120 402.1 0.1 2.2e-120 401.8 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KPA43453.1 - 9.3e-22 77.0 0.0 1.9e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KPA43453.1 - 2.4e-08 33.5 0.0 4.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KPA43453.1 - 0.00012 21.2 0.2 0.00082 18.5 0.1 2.2 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KPA43453.1 - 0.0019 17.7 0.1 0.0036 16.8 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KPA43453.1 - 0.028 13.9 0.4 0.95 8.9 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KPA43453.1 - 0.16 11.2 0.0 16 4.7 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG BRO1 PF03097.18 KPA43454.1 - 8.6e-134 446.2 6.0 8.6e-134 446.2 6.0 2.0 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KPA43454.1 - 1.8e-79 267.1 23.1 4e-79 266.0 23.1 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF416 PF04222.12 KPA43454.1 - 0.084 12.3 6.7 0.17 11.3 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF416) COG2 PF06148.11 KPA43454.1 - 1.6 8.8 10.8 0.13 12.3 2.2 3.2 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ERp29 PF07749.12 KPA43454.1 - 3.1 8.8 9.7 0.5 11.3 0.8 4.0 2 1 2 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain Gp58 PF07902.11 KPA43454.1 - 4.1 5.6 12.9 0.8 7.9 8.7 1.9 2 0 0 2 2 2 0 gp58-like protein DUF1539 PF07560.11 KPA43454.1 - 5.3 7.1 12.7 5 7.2 0.1 4.3 4 1 0 4 4 4 0 Domain of Unknown Function (DUF1539) PMI_typeI PF01238.21 KPA43455.1 - 1.7e-77 261.1 0.0 2.9e-77 260.4 0.0 1.3 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 KPA43455.1 - 0.0003 20.7 0.0 0.051 13.5 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_2 PF07883.11 KPA43455.1 - 0.0081 15.9 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Lactamase_B_2 PF12706.7 KPA43456.1 - 1.5e-07 31.1 0.0 3.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KPA43456.1 - 7.1e-05 23.0 0.1 0.0002 21.5 0.1 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KPA43456.1 - 0.0002 21.4 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KPA43456.1 - 0.15 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Zn_clus PF00172.18 KPA43457.1 - 6.9e-09 35.7 8.1 1.2e-08 34.9 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA43457.1 - 0.003 16.4 0.2 0.0048 15.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KPA43458.1 - 8.4e-71 237.8 9.1 8.4e-71 237.8 9.1 1.5 2 0 0 2 2 2 1 RTA1 like protein p450 PF00067.22 KPA43459.1 - 3.1e-24 85.6 0.0 4.4e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Beta_elim_lyase PF01212.21 KPA43460.1 - 2.1e-63 214.4 0.0 2.6e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DEAD PF00270.29 KPA43461.1 - 4.4e-41 140.6 0.0 1.8e-40 138.6 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA43461.1 - 9.3e-27 93.6 0.1 3.2e-26 91.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA43461.1 - 0.0019 18.2 0.6 0.0067 16.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KPA43461.1 - 0.043 12.6 0.0 3.1 6.4 0.0 2.5 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 TPR_MLP1_2 PF07926.12 KPA43462.1 - 2.1e-38 131.3 52.7 2.9e-38 130.9 32.9 19.1 8 5 9 17 17 17 5 TPR/MLP1/MLP2-like protein Tup_N PF08581.10 KPA43462.1 - 0.0017 18.6 6.5 0.0017 18.6 6.5 21.7 13 5 8 22 22 22 4 Tup N-terminal ERM PF00769.19 KPA43462.1 - 0.0047 16.8 28.4 0.0047 16.8 28.4 12.2 2 2 8 11 11 11 1 Ezrin/radixin/moesin family DUF3693 PF12472.8 KPA43462.1 - 0.059 13.0 0.5 0.23 11.1 0.5 2.0 1 0 0 1 1 1 0 Phage related protein Pox_A_type_inc PF04508.12 KPA43462.1 - 1.2 9.1 26.9 1.8 8.6 0.3 7.8 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat AMP-binding PF00501.28 KPA43463.1 - 6.4e-72 242.5 0.0 1.4e-71 241.3 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Aminotran_5 PF00266.19 KPA43463.1 - 8.7e-44 150.0 0.0 2e-31 109.3 0.0 2.4 1 1 1 2 2 2 2 Aminotransferase class-V NAD_binding_4 PF07993.12 KPA43463.1 - 1.1e-36 126.3 0.0 2.2e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KPA43463.1 - 2.8e-09 36.8 0.0 4.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA43463.1 - 0.00039 19.5 0.0 0.47 9.4 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KPA43463.1 - 0.0012 19.8 0.0 0.0066 17.4 0.0 2.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cys_Met_Meta_PP PF01053.20 KPA43463.1 - 0.0034 16.0 0.0 0.0062 15.1 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NAD_binding_10 PF13460.6 KPA43463.1 - 0.004 17.1 0.0 0.014 15.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KPA43463.1 - 0.0047 17.4 0.0 0.017 15.6 0.0 2.0 2 0 0 2 2 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KPA43463.1 - 0.0061 16.7 0.0 0.022 14.9 0.0 2.0 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KPA43463.1 - 0.008 15.7 0.1 0.052 13.0 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase Aminotran_1_2 PF00155.21 KPA43463.1 - 0.012 14.8 0.0 0.033 13.3 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II GDP_Man_Dehyd PF16363.5 KPA43463.1 - 0.061 12.7 0.1 0.19 11.1 0.1 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KPA43463.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family ABC_membrane PF00664.23 KPA43464.1 - 6.6e-42 144.0 3.6 9e-42 143.6 3.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KPA43464.1 - 1.8e-40 138.7 0.0 5.1e-30 104.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ATPgrasp_N PF18130.1 KPA43464.1 - 1.4e-17 64.0 0.0 5.5e-17 62.1 0.0 2.1 1 0 0 1 1 1 1 ATP-grasp N-terminal domain SMC_N PF02463.19 KPA43464.1 - 1.7e-13 50.5 0.0 1e-05 25.1 0.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Condensation PF00668.20 KPA43464.1 - 4.9e-07 28.8 0.0 8.2e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Condensation domain ATP-grasp_4 PF13535.6 KPA43464.1 - 1e-06 28.5 0.0 3.3e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain AAA_22 PF13401.6 KPA43464.1 - 4.7e-05 23.7 0.0 0.14 12.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain Dala_Dala_lig_C PF07478.13 KPA43464.1 - 0.0001 21.9 0.0 0.00028 20.5 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus DEAD PF00270.29 KPA43464.1 - 0.0017 18.2 0.0 1.5 8.5 0.0 2.8 2 1 0 2 2 2 2 DEAD/DEAH box helicase ATP-grasp_3 PF02655.14 KPA43464.1 - 0.0081 16.2 0.0 0.093 12.8 0.0 2.4 1 1 0 1 1 1 1 ATP-grasp domain AAA_29 PF13555.6 KPA43464.1 - 0.0092 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KPA43464.1 - 0.041 14.1 5.1 9.1 6.6 0.4 4.5 4 2 0 4 4 3 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 KPA43464.1 - 0.048 12.5 0.5 0.1 11.4 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_16 PF13191.6 KPA43464.1 - 0.051 14.0 2.6 0.23 11.9 0.3 2.8 2 1 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KPA43464.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 KPA43464.1 - 0.087 12.6 0.0 7 6.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 KPA43464.1 - 0.19 10.8 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 KPA43464.1 - 0.21 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AMP-binding PF00501.28 KPA43465.1 - 4.1e-74 249.7 0.0 5.4e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Methyltransf_25 PF13649.6 KPA43465.1 - 4.8e-06 27.2 0.0 1.4e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA43465.1 - 1.6e-05 25.6 0.0 5.8e-05 23.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA43465.1 - 1.6e-05 25.5 0.0 4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA43465.1 - 0.00074 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA43465.1 - 0.0027 17.5 0.0 0.0084 16.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KPA43466.1 - 3.7e-12 46.4 0.0 6.2e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thioesterase PF00975.20 KPA43466.1 - 2.5e-09 37.6 1.3 3.9e-09 37.0 0.1 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KPA43466.1 - 4e-09 37.4 1.5 8.7e-07 29.8 1.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA43466.1 - 5.1e-06 26.3 0.5 8.9e-06 25.5 0.5 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA43466.1 - 0.006 15.9 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KPA43466.1 - 0.22 11.0 0.0 2.4 7.6 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) TMEM154 PF15102.6 KPA43467.1 - 0.024 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Glycophorin_A PF01102.18 KPA43467.1 - 0.033 14.4 0.1 0.07 13.4 0.1 1.5 1 0 0 1 1 1 0 Glycophorin A RCR PF12273.8 KPA43467.1 - 0.057 14.1 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF2897 PF11446.8 KPA43468.1 - 0.23 11.4 1.9 0.56 10.1 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Hce2 PF14856.6 KPA43470.1 - 5.2e-18 65.2 0.3 7.3e-18 64.7 0.3 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor NACHT_N PF17100.5 KPA43471.1 - 2.6e-33 115.7 0.0 3.4e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase RCDG1 PF15725.5 KPA43471.1 - 0.013 15.9 1.1 0.028 14.8 1.1 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Peptidase_Prp PF04327.12 KPA43471.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Cysteine protease Prp Amidoligase_2 PF12224.8 KPA43472.1 - 1.4e-12 47.8 0.0 5.8e-09 36.0 0.0 2.5 2 1 0 2 2 2 2 Putative amidoligase enzyme Hira PF07569.11 KPA43473.1 - 2.5e-81 272.6 0.0 6.6e-81 271.3 0.0 1.8 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KPA43473.1 - 1.9e-30 104.4 24.4 1.4e-05 25.8 0.0 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA43473.1 - 6.2e-16 58.5 0.0 0.0081 16.4 0.0 6.7 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KPA43473.1 - 3e-10 39.7 0.5 7.8e-10 38.4 0.5 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KPA43473.1 - 6.4e-05 22.8 2.5 15 5.7 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KPA43473.1 - 0.01 14.8 0.8 1.4 7.8 0.0 3.9 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KPA43473.1 - 0.017 13.2 0.0 0.07 11.1 0.0 1.9 2 0 0 2 2 2 0 IKI3 family DUF3810 PF12725.7 KPA43473.1 - 0.32 10.3 1.4 0.5 9.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) RR_TM4-6 PF06459.12 KPA43473.1 - 1.4 8.6 7.5 2.7 7.8 7.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_transf_15 PF01793.16 KPA43474.1 - 3.8e-51 174.3 2.1 3.2e-38 131.8 0.5 2.1 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Nuc_sug_transp PF04142.15 KPA43475.1 - 2.7e-98 329.0 6.1 3.6e-98 328.6 6.1 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KPA43475.1 - 2.5e-08 34.2 26.5 4.1e-06 27.0 7.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KPA43475.1 - 7.3e-05 22.1 12.4 0.00038 19.8 3.8 2.2 2 0 0 2 2 2 2 UAA transporter family YSIRK_signal PF04650.17 KPA43475.1 - 0.089 12.7 2.9 0.35 10.8 2.9 2.1 1 0 0 1 1 1 0 YSIRK type signal peptide TPT PF03151.16 KPA43475.1 - 0.2 11.0 12.7 0.096 12.0 0.4 2.6 2 2 0 2 2 2 0 Triose-phosphate Transporter family CRT-like PF08627.10 KPA43475.1 - 0.2 10.5 7.2 0.14 11.1 0.4 2.2 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like NTP_transferase PF00483.23 KPA43476.1 - 1.1e-32 113.6 0.0 1.5e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KPA43476.1 - 9.8e-11 40.9 5.6 1.2e-06 28.0 0.0 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KPA43476.1 - 7.4e-07 29.7 0.0 1.1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glycos_transf_2 PF00535.26 KPA43476.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 ydhR PF08803.11 KPA43476.1 - 0.078 12.9 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Putative mono-oxygenase ydhR DUF2968 PF11180.8 KPA43476.1 - 0.094 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Hexapep_2 PF14602.6 KPA43476.1 - 0.7 9.7 3.1 5.6 6.8 0.0 3.4 4 1 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase CDO_I PF05995.12 KPA43477.1 - 3e-37 127.5 0.0 3.4e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KPA43477.1 - 0.007 15.8 0.0 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO SLAC1 PF03595.17 KPA43478.1 - 3e-54 184.5 16.0 3.3e-54 184.3 16.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel QueT PF06177.11 KPA43478.1 - 0.31 11.4 11.8 3.6 8.0 6.5 2.6 2 1 0 2 2 2 0 QueT transporter Wyosine_form PF08608.12 KPA43479.1 - 1e-25 89.9 0.0 3.7e-25 88.1 0.0 2.1 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KPA43479.1 - 3.2e-21 76.4 0.0 1e-20 74.8 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 KPA43479.1 - 5.7e-11 42.8 0.9 8.6e-08 32.5 0.4 3.6 2 1 0 2 2 2 2 Flavodoxin MAS20 PF02064.15 KPA43480.1 - 2.1e-41 141.0 1.4 2.5e-41 140.8 1.4 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Rhabdo_ncap PF00945.18 KPA43480.1 - 0.044 12.7 0.4 0.051 12.5 0.4 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Exo84_C PF16528.5 KPA43481.1 - 1e-77 260.6 0.4 1e-77 260.6 0.4 2.2 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KPA43481.1 - 2.4e-16 59.6 2.6 2.4e-16 59.6 2.6 2.2 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.11 KPA43481.1 - 0.0047 17.0 0.3 0.11 12.5 0.0 2.4 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 RecX PF02631.16 KPA43481.1 - 0.029 14.8 1.2 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 RecX family DUF4449 PF14613.6 KPA43481.1 - 0.065 13.3 4.0 0.049 13.7 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) H-kinase_dim PF02895.14 KPA43481.1 - 0.85 10.0 3.8 4.2 7.8 0.6 2.8 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain SKA2 PF16740.5 KPA43481.1 - 0.87 9.4 5.2 0.21 11.4 1.6 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 TSC22 PF01166.18 KPA43481.1 - 5.1 7.5 5.9 12 6.3 0.1 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family Metallophos PF00149.28 KPA43482.1 - 3.5e-38 132.2 0.5 5.6e-38 131.5 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KPA43482.1 - 0.089 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF3112 PF11309.8 KPA43483.1 - 8.7e-15 54.8 11.5 1.2e-10 41.2 0.6 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) DUF4345 PF14248.6 KPA43483.1 - 0.0073 16.2 0.2 0.0073 16.2 0.2 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4345) Oxidored_FMN PF00724.20 KPA43484.1 - 2.3e-88 296.7 0.0 3.1e-88 296.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RNase_H PF00075.24 KPA43484.1 - 0.0062 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 RNase H SH3_9 PF14604.6 KPA43485.1 - 5e-06 26.3 0.1 1e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPA43485.1 - 1.1e-05 25.0 0.1 2.2e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain DUF4690 PF15756.5 KPA43485.1 - 0.002 18.7 0.0 0.0064 17.1 0.0 1.9 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 KPA43485.1 - 0.0024 18.0 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 Podoplanin TMEM51 PF15345.6 KPA43485.1 - 0.025 14.4 0.0 0.058 13.2 0.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 DAP10 PF07213.11 KPA43485.1 - 0.43 10.6 2.7 0.63 10.0 0.0 2.6 2 0 0 2 2 2 0 DAP10 membrane protein DcpS PF05652.12 KPA43486.1 - 1e-37 129.1 0.0 1.6e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KPA43486.1 - 8.8e-33 113.2 0.1 1.4e-32 112.5 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF1938 PF09153.10 KPA43486.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) GILT PF03227.16 KPA43487.1 - 2.6e-17 63.0 0.0 4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_1 PF00349.21 KPA43488.1 - 3.9e-50 170.5 0.0 5.1e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KPA43488.1 - 1.8e-47 161.8 0.0 2.5e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase VARLMGL PF14383.6 KPA43488.1 - 0.36 10.4 1.7 0.7 9.5 0.1 2.1 2 0 0 2 2 2 0 DUF761-associated sequence motif MFS_1 PF07690.16 KPA43489.1 - 1.1e-39 136.3 43.6 1.1e-39 136.3 43.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA43489.1 - 5.2e-11 42.1 10.9 5.2e-11 42.1 10.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPA43489.1 - 3.1e-07 29.2 16.8 5.7e-07 28.3 16.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Myb_Cef PF11831.8 KPA43490.1 - 1.1e-54 185.5 8.5 1.1e-54 185.5 8.5 3.3 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KPA43490.1 - 1.3e-22 79.8 4.8 8.5e-11 41.9 0.9 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPA43490.1 - 1.3e-20 73.4 7.8 7.1e-15 55.0 2.9 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KPA43490.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.0 4 0 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MFS_1 PF07690.16 KPA43491.1 - 2.5e-26 92.4 27.6 9.2e-16 57.7 13.7 2.7 2 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA43491.1 - 0.00071 18.6 5.5 0.00071 18.6 5.5 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter DUF5326 PF17260.2 KPA43491.1 - 0.037 14.1 0.8 0.037 14.1 0.8 3.2 4 0 0 4 4 4 0 Family of unknown function (DUF5326) HIT PF01230.23 KPA43492.1 - 2.8e-20 72.9 0.2 4.5e-20 72.2 0.2 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KPA43492.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 KPA43492.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain MFS_1 PF07690.16 KPA43493.1 - 1.5e-30 106.4 25.5 2.9e-27 95.5 5.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA43493.1 - 2.1e-09 36.8 2.5 2.1e-09 36.8 2.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter TPR_1 PF00515.28 KPA43494.1 - 2e-06 27.4 5.4 0.02 14.7 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPA43494.1 - 1.6e-05 24.7 5.0 0.35 11.1 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA43494.1 - 0.0032 17.6 0.9 0.0078 16.4 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KPA43494.1 - 0.007 16.5 2.9 2.4 8.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPA43494.1 - 0.054 14.0 0.6 0.18 12.3 0.6 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DNA_topoisoIV PF00521.20 KPA43496.1 - 4.3e-121 404.8 0.0 1e-120 403.6 0.0 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KPA43496.1 - 1.4e-48 164.4 2.7 1.4e-48 164.4 2.7 2.4 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KPA43496.1 - 5.2e-26 91.2 0.4 1.2e-25 90.0 0.4 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KPA43496.1 - 5.1e-12 46.3 0.0 1.2e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KPA43496.1 - 4.2e-06 26.9 0.0 1.8e-05 24.9 0.0 2.1 1 0 0 1 1 1 1 Toprim domain BBIP10 PF14777.6 KPA43496.1 - 0.12 11.9 1.3 0.32 10.6 1.3 1.7 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 V-ATPase_G PF03179.15 KPA43496.1 - 0.27 11.8 5.0 5.3 7.6 0.4 3.4 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit TAP42 PF04177.12 KPA43497.1 - 4.4e-101 338.2 0.2 5e-101 338.0 0.2 1.0 1 0 0 1 1 1 1 TAP42-like family T2SSK PF03934.13 KPA43499.1 - 0.025 14.0 0.3 0.044 13.2 0.3 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K AAA_18 PF13238.6 KPA43500.1 - 2.1e-06 28.3 0.0 3.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RabGAP-TBC PF00566.18 KPA43501.1 - 5.4e-47 160.2 0.0 2.2e-46 158.2 0.0 2.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Prominin PF05478.11 KPA43501.1 - 0.96 7.3 15.4 0.015 13.3 6.5 2.0 2 0 0 2 2 2 0 Prominin Sec34 PF04136.15 KPA43501.1 - 1.6 8.6 16.1 0.39 10.6 6.1 2.9 2 0 0 2 2 2 0 Sec34-like family DUF1664 PF07889.12 KPA43501.1 - 2.3 8.3 15.4 0.15 12.1 5.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) VPS11_C PF12451.8 KPA43501.1 - 4.3 7.6 5.8 2.6 8.3 2.0 2.7 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Reticulon PF02453.17 KPA43502.1 - 3e-34 118.2 3.2 4.3e-34 117.8 3.2 1.2 1 0 0 1 1 1 1 Reticulon AHSP PF09236.10 KPA43502.1 - 0.014 15.8 0.4 0.12 12.8 0.1 2.3 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein RIBIOP_C PF04950.12 KPA43503.1 - 4.3e-93 311.9 0.1 4.3e-93 311.9 0.1 2.3 3 0 0 3 3 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KPA43503.1 - 4.7e-28 97.1 0.1 1.8e-27 95.2 0.0 2.1 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KPA43503.1 - 1.4e-05 25.4 0.3 7.4e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA43503.1 - 5.6e-05 23.6 0.1 0.0002 21.8 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 KPA43503.1 - 0.00041 20.8 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KPA43503.1 - 0.00046 20.4 0.3 0.0024 18.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KPA43503.1 - 0.00098 19.2 0.0 0.0032 17.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KPA43503.1 - 0.001 19.0 0.0 0.0024 17.8 0.0 1.7 1 1 0 1 1 1 1 NACHT domain GTP_EFTU PF00009.27 KPA43503.1 - 0.0011 18.5 0.0 0.4 10.2 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KPA43503.1 - 0.0016 19.0 0.2 0.007 16.9 0.0 2.2 2 0 0 2 2 1 1 ABC transporter RNA_helicase PF00910.22 KPA43503.1 - 0.0016 18.8 0.1 0.006 17.0 0.0 2.0 2 0 0 2 2 2 1 RNA helicase Ploopntkinase3 PF18751.1 KPA43503.1 - 0.0019 18.1 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 PduV-EutP PF10662.9 KPA43503.1 - 0.0042 16.8 0.0 0.015 15.0 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 KPA43503.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KPA43503.1 - 0.0057 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 KPA43503.1 - 0.011 16.1 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KPA43503.1 - 0.011 15.6 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 KPA43503.1 - 0.016 15.3 0.0 0.057 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KPA43503.1 - 0.019 14.9 0.2 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain MobB PF03205.14 KPA43503.1 - 0.021 14.7 1.3 0.64 9.9 0.1 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KPA43503.1 - 0.037 13.6 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KPA43503.1 - 0.039 14.5 0.0 0.039 14.5 0.0 3.6 4 0 0 4 4 3 0 AAA domain AAA_7 PF12775.7 KPA43503.1 - 0.04 13.4 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Roc PF08477.13 KPA43503.1 - 0.044 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KPA43503.1 - 0.058 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 KPA43503.1 - 0.058 13.6 2.5 0.08 13.2 0.0 2.5 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 KPA43503.1 - 0.059 13.3 0.5 0.18 11.7 0.0 2.0 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KPA43503.1 - 0.073 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KPA43503.1 - 0.15 12.1 0.0 0.84 9.6 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 KPA43503.1 - 0.17 11.3 1.5 0.67 9.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein DASH_Ask1 PF08655.10 KPA43505.1 - 6.6e-30 102.8 0.1 1e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 SBF2 PF12335.8 KPA43505.1 - 1.1 8.8 3.0 1.8 8.1 3.0 1.5 1 1 0 1 1 1 0 Myotubularin protein GCP_C_terminal PF04130.13 KPA43506.1 - 2.1e-80 270.5 0.2 4.7e-80 269.4 0.2 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KPA43506.1 - 8.1e-27 94.6 0.0 1.2e-26 94.1 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal PDE6_gamma PF04868.12 KPA43506.1 - 0.24 11.7 1.0 23 5.3 0.1 2.9 3 0 0 3 3 3 0 Retinal cGMP phosphodiesterase, gamma subunit Eaf7 PF07904.13 KPA43507.1 - 5.7e-27 94.2 0.2 5.7e-27 94.2 0.2 2.5 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 TFIIF_alpha PF05793.12 KPA43507.1 - 0.0013 17.5 23.2 0.0023 16.6 23.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4551 PF15087.6 KPA43507.1 - 0.35 9.6 8.7 0.52 9.1 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CYYR1 PF10873.8 KPA43507.1 - 0.76 10.2 1.8 1.4 9.3 1.8 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Nop14 PF04147.12 KPA43507.1 - 1.5 7.0 22.1 2.1 6.4 22.1 1.4 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 KPA43507.1 - 2.6 6.0 14.7 4 5.4 14.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 KPA43507.1 - 3.8 5.5 19.4 7.7 4.5 19.4 1.5 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-binding PF00249.31 KPA43508.1 - 0.0013 18.9 0.0 0.0033 17.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Helicase_C PF00271.31 KPA43509.1 - 6e-16 58.8 0.2 3.4e-15 56.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA43509.1 - 1.3e-09 38.3 0.0 2.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPA43509.1 - 2.2e-06 27.6 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KPA43509.1 - 0.0065 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Plus-3 PF03126.18 KPA43509.1 - 0.04 14.4 0.0 2.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Plus-3 domain DUF2034 PF10356.9 KPA43511.1 - 1.3e-25 89.9 0.0 1.3e-12 47.6 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KPA43511.1 - 8.9e-07 28.9 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease MOR2-PAG1_N PF14222.6 KPA43512.1 - 1.5e-222 740.4 0.0 2.5e-222 739.7 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KPA43512.1 - 1e-91 307.3 0.1 5.7e-91 304.9 0.0 2.4 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KPA43512.1 - 2e-43 148.3 9.6 1.9e-16 59.0 0.1 3.3 1 1 2 3 3 3 3 Cell morphogenesis central region Cnd1 PF12717.7 KPA43512.1 - 0.27 11.3 2.4 4.7 7.2 0.3 3.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 FAD_binding_1 PF00667.20 KPA43513.1 - 6.3e-63 212.3 0.0 9.5e-63 211.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KPA43513.1 - 1e-33 116.6 0.3 1.8e-33 115.7 0.3 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KPA43513.1 - 2.7e-20 73.0 0.0 1.4e-19 70.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KPA43513.1 - 0.06 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain RRM_1 PF00076.22 KPA43514.1 - 6.6e-20 70.7 0.0 6.2e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.22 KPA43515.1 - 6.3e-42 143.3 0.0 4.6e-41 140.5 0.1 2.2 2 1 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 KPA43515.1 - 1.3e-31 108.6 0.1 3.6e-31 107.2 0.1 1.8 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 KPA43515.1 - 8.9e-08 32.3 0.4 0.00031 20.8 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KPA43515.1 - 1.2e-06 28.0 0.0 0.005 16.2 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.13 KPA43515.1 - 0.0037 17.3 5.8 0.0046 17.0 5.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 KPA43515.1 - 0.044 13.8 3.4 0.077 13.0 3.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.12 KPA43515.1 - 1.2 8.5 8.1 1.7 7.9 8.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.6 KPA43515.1 - 2 8.1 4.1 3.5 7.3 4.1 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KPA43515.1 - 4.6 6.5 9.0 6.8 5.9 9.0 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KPA43515.1 - 5.5 7.4 12.3 13 6.3 12.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4637 PF15470.6 KPA43515.1 - 8.8 6.0 7.8 49 3.6 5.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) RPN1_RPN2_N PF17781.1 KPA43516.1 - 1.5e-113 379.3 7.0 2.8e-113 378.4 6.8 1.6 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KPA43516.1 - 7e-29 99.6 0.0 1.3e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KPA43516.1 - 3.6e-24 83.9 15.9 8.9e-07 29.0 0.2 8.8 8 1 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KPA43516.1 - 3.7e-08 33.7 0.9 0.011 16.1 0.0 4.6 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.22 KPA43516.1 - 0.0053 16.9 0.0 48 4.6 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat MIF4G_like_2 PF09090.11 KPA43516.1 - 0.4 10.1 3.4 1 8.8 3.4 1.6 1 0 0 1 1 1 0 MIF4G like Tho2 PF11262.8 KPA43516.1 - 2.4 7.3 6.4 1.2 8.2 4.0 1.7 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 OPT PF03169.15 KPA43517.1 - 3.8e-205 683.2 35.0 4.4e-205 682.9 35.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1453 PF07301.11 KPA43517.1 - 0.0026 17.8 0.6 0.011 15.7 0.6 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1453) DUF4407 PF14362.6 KPA43517.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) 5-FTHF_cyc-lig PF01812.20 KPA43518.1 - 1.5e-30 106.4 0.0 1.9e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Xpo1 PF08389.12 KPA43519.1 - 7e-26 91.1 3.5 6.6e-25 87.9 0.5 3.7 4 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 KPA43519.1 - 1.6e-06 27.9 0.1 6.2e-06 26.0 0.1 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain UME PF08064.13 KPA43519.1 - 4.5e-05 23.3 2.8 1.3 9.0 0.0 5.4 4 1 1 5 5 5 2 UME (NUC010) domain Importin_rep_3 PF18806.1 KPA43519.1 - 0.018 15.0 0.0 0.76 9.9 0.0 3.2 2 0 0 2 2 2 0 Importin 13 repeat Ribosomal_S5_C PF03719.15 KPA43519.1 - 0.02 14.3 0.0 0.057 12.9 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Adaptin_N PF01602.20 KPA43519.1 - 0.045 12.3 0.7 0.45 9.0 0.2 2.4 2 0 0 2 2 2 0 Adaptin N terminal region Ras PF00071.22 KPA43521.1 - 9.5e-58 194.4 0.2 1.1e-57 194.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA43521.1 - 7e-20 71.4 0.0 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA43521.1 - 4.6e-07 29.5 0.0 5.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPA43521.1 - 7e-06 25.7 0.1 4e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPA43521.1 - 0.00013 21.9 0.3 0.63 9.9 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KPA43521.1 - 0.003 17.5 0.0 0.0065 16.5 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KPA43521.1 - 0.0094 16.0 0.0 0.019 15.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPA43521.1 - 0.044 13.3 0.0 0.16 11.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KPA43521.1 - 0.12 12.1 1.5 1.4 8.6 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MoCF_biosynth PF00994.24 KPA43522.1 - 3.1e-35 121.0 0.0 8.7e-35 119.5 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.20 KPA43523.1 - 1.1e-17 64.0 0.0 1.3e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ParA PF10609.9 KPA43524.1 - 2.3e-96 322.0 0.0 2.8e-96 321.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KPA43524.1 - 6.3e-08 32.7 0.0 1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KPA43524.1 - 0.00026 20.9 0.1 0.0035 17.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KPA43524.1 - 0.00038 19.7 0.2 0.0015 17.8 0.1 2.0 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KPA43524.1 - 0.0047 16.5 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KPA43524.1 - 0.0074 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase Fer4_NifH PF00142.18 KPA43524.1 - 0.014 14.8 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Rad17 PF03215.15 KPA43524.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain MipZ PF09140.11 KPA43524.1 - 0.037 13.3 0.0 0.077 12.3 0.0 1.5 1 1 0 1 1 1 0 ATPase MipZ Zn_Tnp_IS1595 PF12760.7 KPA43524.1 - 0.093 12.7 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain RNA_helicase PF00910.22 KPA43524.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KPA43524.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_26 PF13500.6 KPA43524.1 - 0.11 12.3 0.0 10 5.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KPA43524.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KPA43524.1 - 0.17 12.3 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 KPA43524.1 - 0.21 11.2 0.0 0.36 10.4 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain HEAT_2 PF13646.6 KPA43525.1 - 1.1e-26 93.1 6.0 5.8e-13 49.1 0.1 3.9 2 2 1 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 KPA43525.1 - 6.4e-19 66.7 6.7 0.01 16.5 0.4 6.6 6 1 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KPA43525.1 - 2.7e-07 30.3 3.6 0.52 10.7 0.0 6.2 6 1 1 7 7 7 2 HEAT repeat Arm PF00514.23 KPA43525.1 - 0.007 16.4 3.0 2.7 8.1 0.1 3.3 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KPA43525.1 - 0.02 15.4 9.4 0.56 10.8 0.0 4.6 3 2 2 5 5 5 0 HEAT-like repeat RuvA_C PF07499.13 KPA43525.1 - 0.023 15.1 0.1 17 6.0 0.0 2.9 2 0 0 2 2 2 0 RuvA, C-terminal domain Cnd1 PF12717.7 KPA43525.1 - 0.045 13.8 0.0 1.6 8.8 0.0 2.7 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 AAA_lid_1 PF17857.1 KPA43525.1 - 0.18 12.0 0.1 29 4.9 0.0 3.0 3 0 0 3 3 3 0 AAA+ lid domain TFIIS_C PF01096.18 KPA43526.1 - 7.1e-12 45.0 1.7 7.1e-12 45.0 1.7 3.2 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KPA43526.1 - 6.8e-05 22.7 2.8 6.8e-05 22.7 2.8 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit UCH_1 PF13423.6 KPA43526.1 - 0.00022 21.0 3.1 0.00025 20.7 3.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DZR PF12773.7 KPA43526.1 - 0.00076 19.5 4.8 0.29 11.2 2.0 2.3 2 0 0 2 2 2 2 Double zinc ribbon HypA PF01155.19 KPA43526.1 - 0.0023 17.9 5.9 0.27 11.3 1.5 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KPA43526.1 - 0.003 17.2 13.8 2 8.2 0.1 3.3 3 0 0 3 3 3 3 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KPA43526.1 - 0.0074 16.2 4.7 1.1 9.3 0.1 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 KPA43526.1 - 0.013 15.7 7.4 9 6.5 5.6 3.2 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_7 PF02591.15 KPA43526.1 - 0.033 14.4 7.7 11 6.3 0.1 3.7 4 0 0 4 4 4 0 C4-type zinc ribbon domain ArfGap PF01412.18 KPA43526.1 - 0.14 12.2 3.4 2.1 8.4 0.7 2.1 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Ribosomal_L37ae PF01780.19 KPA43526.1 - 0.15 12.2 0.2 0.15 12.2 0.2 2.2 2 0 0 2 2 2 0 Ribosomal L37ae protein family RIIa PF02197.17 KPA43526.1 - 0.16 11.7 0.0 0.67 9.7 0.0 1.9 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit OrfB_Zn_ribbon PF07282.11 KPA43526.1 - 0.2 11.6 7.1 1.8 8.6 1.2 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RecR PF02132.15 KPA43526.1 - 0.25 11.0 5.7 0.2 11.3 1.7 2.3 2 0 0 2 2 2 0 RecR protein Lar_restr_allev PF14354.6 KPA43526.1 - 0.3 11.5 10.6 1.6 9.2 0.8 3.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 KPA43526.1 - 0.58 10.3 0.2 0.58 10.3 0.2 2.8 2 1 0 2 2 2 0 Zinc ribbon domain zf-ISL3 PF14690.6 KPA43526.1 - 0.91 10.2 9.3 5.3 7.8 0.1 3.1 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.6 KPA43526.1 - 1 8.9 8.7 2.9 7.4 0.4 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Nipped-B_C PF12830.7 KPA43527.1 - 2e-49 168.1 4.0 1.8e-47 161.7 1.5 3.6 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KPA43527.1 - 9.5e-06 25.8 4.0 1.3e-05 25.4 0.3 3.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KPA43527.1 - 9.3e-05 22.4 6.2 0.32 11.4 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KPA43527.1 - 0.0022 18.1 0.1 0.024 14.7 0.0 2.7 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KPA43527.1 - 0.021 14.4 0.1 2.7 7.5 0.0 2.9 2 1 0 2 2 2 0 CLASP N terminal Cnd3 PF12719.7 KPA43527.1 - 0.052 12.7 0.0 1.1 8.4 0.0 3.0 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain AT_hook PF02178.19 KPA43527.1 - 0.57 10.2 6.5 2 8.5 6.5 1.9 1 0 0 1 1 1 0 AT hook motif Na_Ca_ex PF01699.24 KPA43528.1 - 2.3e-45 154.2 37.7 7.7e-25 87.6 14.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein IML1 PF12257.8 KPA43529.1 - 1.5e-115 385.3 0.0 2.1e-115 384.8 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KPA43529.1 - 1.1e-26 92.7 0.1 2.2e-26 91.7 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Fungal_trans PF04082.18 KPA43530.1 - 2.4e-62 210.4 0.2 3.6e-62 209.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPA43530.1 - 1.7e-07 31.3 9.9 0.00077 19.8 0.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA43530.1 - 0.66 11.0 18.3 0.32 12.0 1.0 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger INSIG PF07281.12 KPA43532.1 - 2.1e-82 275.9 1.0 2.7e-82 275.5 1.0 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) UPF0139 PF03669.13 KPA43532.1 - 0.081 12.8 0.3 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) WD40 PF00400.32 KPA43533.1 - 3e-11 43.7 0.3 0.11 13.4 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Pkinase PF00069.25 KPA43534.1 - 8.8e-40 136.7 0.0 1.3e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA43534.1 - 1e-28 100.4 0.0 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPA43534.1 - 0.0014 18.6 0.2 0.092 12.7 0.0 3.0 4 1 1 5 5 5 1 Phosphotransferase enzyme family DUF1168 PF06658.12 KPA43534.1 - 0.013 15.3 0.7 0.028 14.2 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Pkinase_fungal PF17667.1 KPA43534.1 - 0.03 13.1 0.0 0.064 12.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KPA43534.1 - 0.045 13.1 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CYSTM PF12734.7 KPA43535.1 - 8.4 6.8 23.3 14 6.1 23.3 1.6 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Pkinase_Tyr PF07714.17 KPA43536.1 - 9.4e-06 25.1 0.0 2.5e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KPA43536.1 - 0.00017 21.0 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HeLo PF14479.6 KPA43537.1 - 6.7e-46 156.7 2.7 9.2e-46 156.3 2.7 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Zn_clus PF00172.18 KPA43538.1 - 2e-10 40.6 5.2 4.1e-10 39.6 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA43538.1 - 2e-08 33.6 1.2 7e-08 31.8 0.0 2.3 1 1 0 2 2 2 1 Fungal specific transcription factor domain DUF2457 PF10446.9 KPA43538.1 - 2.7 7.1 3.9 4.9 6.2 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ABC2_membrane PF01061.24 KPA43539.1 - 1.1e-27 96.8 25.7 1.7e-27 96.2 25.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KPA43539.1 - 5.9e-26 91.6 0.0 1e-25 90.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KPA43539.1 - 2.2e-06 27.6 0.0 8.7e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KPA43539.1 - 2.4e-05 24.8 0.1 4.4e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KPA43539.1 - 2.7e-05 23.8 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KPA43539.1 - 0.00045 20.1 0.0 0.75 9.5 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KPA43539.1 - 0.00073 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain SMC_N PF02463.19 KPA43539.1 - 0.00084 18.8 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KPA43539.1 - 0.0013 19.0 0.0 0.0034 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KPA43539.1 - 0.0071 16.3 0.0 0.033 14.1 0.0 1.9 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KPA43539.1 - 0.0084 16.1 0.0 0.024 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KPA43539.1 - 0.0096 16.3 0.0 0.033 14.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KPA43539.1 - 0.015 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPA43539.1 - 0.016 15.8 0.0 0.038 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPA43539.1 - 0.017 15.5 0.0 0.046 14.1 0.0 1.7 2 0 0 2 2 1 0 RNA helicase PDR_CDR PF06422.12 KPA43539.1 - 0.021 14.7 0.2 0.021 14.7 0.2 2.5 2 0 0 2 2 2 0 CDR ABC transporter AAA_29 PF13555.6 KPA43539.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KPA43539.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KPA43539.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KPA43539.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 KPA43539.1 - 0.15 11.7 0.0 0.91 9.1 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 KPA43539.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KPA43539.1 - 0.15 11.8 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Cytochrom_B561 PF03188.16 KPA43540.1 - 0.012 15.8 6.2 0.023 14.8 6.2 1.4 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KPA43540.1 - 0.033 14.3 11.4 0.1 12.7 0.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) Herpes_UL17 PF04559.12 KPA43540.1 - 1.2 7.8 6.4 0.76 8.5 4.0 1.7 2 0 0 2 2 2 0 Herpesvirus UL17 protein Phage_holin_2_4 PF16082.5 KPA43540.1 - 1.8 8.4 0.0 1.8 8.4 0.0 3.3 4 0 0 4 4 4 0 Bacteriophage holin family, superfamily II-like Phosphodiest PF01663.22 KPA43541.1 - 5.3e-14 52.6 0.0 9.7e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KPA43541.1 - 4.3e-06 26.3 0.0 1.6e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KPA43541.1 - 0.0058 16.0 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily MaoC_dehydratas PF01575.19 KPA43542.1 - 1.8e-07 30.7 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain CMAS PF02353.20 KPA43543.1 - 2.6e-64 217.2 0.1 3.5e-64 216.7 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KPA43543.1 - 2e-11 44.0 0.0 4.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA43543.1 - 2.2e-10 41.1 0.0 4.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA43543.1 - 1.1e-09 38.9 0.0 2.5e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA43543.1 - 0.0044 17.7 0.0 0.012 16.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA43543.1 - 0.031 14.1 0.0 0.16 11.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KPA43543.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 KPA43543.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KPA43543.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KPA43543.1 - 0.2 11.7 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SH3BGR PF04908.15 KPA43545.1 - 8.3e-05 22.7 3.1 0.00013 22.1 0.0 2.9 2 1 1 3 3 3 1 SH3-binding, glutamic acid-rich protein AAA PF00004.29 KPA43546.1 - 2e-50 170.6 0.0 8.1e-43 146.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA43546.1 - 7.4e-06 25.7 3.2 0.034 14.0 0.1 2.9 3 0 0 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 KPA43546.1 - 7.5e-05 22.5 0.0 0.00053 19.8 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPA43546.1 - 8.9e-05 22.9 0.3 0.02 15.3 0.0 3.3 2 1 1 3 3 2 1 AAA ATPase domain Parvo_NS1 PF01057.17 KPA43546.1 - 0.00069 18.8 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 KPA43546.1 - 0.0016 18.6 0.0 0.009 16.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KPA43546.1 - 0.0017 17.9 0.3 0.025 14.1 0.0 2.8 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KPA43546.1 - 0.0029 18.0 0.0 0.041 14.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 KPA43546.1 - 0.0073 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KPA43546.1 - 0.0082 16.4 0.0 0.038 14.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KPA43546.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KPA43546.1 - 0.024 14.0 0.1 0.057 12.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KPA43546.1 - 0.026 14.5 0.0 0.14 12.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KPA43546.1 - 0.039 13.3 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 KPA43546.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KPA43546.1 - 0.053 13.7 0.0 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KPA43546.1 - 0.054 13.5 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KPA43546.1 - 0.073 13.6 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KPA43546.1 - 0.075 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KPA43546.1 - 0.093 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KPA43546.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KPA43546.1 - 0.17 11.9 0.0 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KPA43546.1 - 0.22 10.7 0.0 4 6.6 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Abhydro_lipase PF04083.16 KPA43547.1 - 6.7e-21 73.6 0.0 1.8e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KPA43547.1 - 7.2e-05 22.5 0.1 0.00023 20.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA43547.1 - 0.00034 20.0 0.0 0.0018 17.6 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 GDE_C PF06202.14 KPA43547.1 - 0.15 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase ATP11 PF06644.11 KPA43548.1 - 1.1e-101 340.2 0.0 1.3e-101 339.9 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein MMS19_N PF14500.6 KPA43549.1 - 2.1e-52 178.3 0.2 7.4e-52 176.5 0.1 2.0 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KPA43549.1 - 7e-21 74.8 2.1 7.8e-20 71.4 2.6 2.3 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal TAN PF11640.8 KPA43549.1 - 0.14 12.3 1.2 6.6 6.8 0.0 3.9 5 0 0 5 5 5 0 Telomere-length maintenance and DNA damage repair SPC25 PF06703.11 KPA43550.1 - 4.8e-53 179.3 0.4 5.7e-53 179.0 0.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) OKR_DC_1_N PF03709.15 KPA43550.1 - 0.14 12.5 0.0 0.43 10.9 0.0 1.9 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain EMC3_TMCO1 PF01956.16 KPA43551.1 - 2.3e-54 183.7 1.1 3e-54 183.3 1.1 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like TatC PF00902.18 KPA43551.1 - 0.014 15.3 0.8 0.039 13.8 1.0 1.6 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) RNA_pol_Rbc25 PF08292.12 KPA43552.1 - 6.6e-32 110.5 1.5 1.4e-30 106.1 1.5 2.1 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KPA43552.1 - 2.2e-13 50.4 0.0 3.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.9 KPA43553.1 - 8.8e-06 25.5 0.0 2.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 KPA43553.1 - 0.036 14.1 6.8 0.064 13.3 6.8 1.4 1 0 0 1 1 1 0 Zinc finger domain DUF4509 PF14970.6 KPA43553.1 - 0.047 13.6 0.7 0.079 12.9 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) zf-CCCH PF00642.24 KPA43553.1 - 0.19 11.7 5.9 0.39 10.7 5.9 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PIEZO PF15917.5 KPA43553.1 - 0.21 11.0 3.2 0.38 10.2 3.2 1.4 1 0 0 1 1 1 0 Piezo SPT2 PF08243.11 KPA43554.1 - 2.6e-10 40.8 26.7 1.6e-07 31.8 26.7 2.3 1 1 0 1 1 1 1 SPT2 chromatin protein Cwf_Cwc_15 PF04889.12 KPA43554.1 - 0.067 12.9 9.0 0.12 12.1 9.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRM_3 PF08777.11 KPA43554.1 - 0.069 13.2 1.4 0.13 12.3 1.4 1.4 1 0 0 1 1 1 0 RNA binding motif Ribosomal_60s PF00428.19 KPA43555.1 - 1.9e-27 95.6 11.2 2.2e-27 95.4 11.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KPA43555.1 - 0.17 12.2 0.5 0.23 11.9 0.0 1.4 2 0 0 2 2 2 0 EF-hand domain Trp_oprn_chp PF09534.10 KPA43556.1 - 0.0018 18.1 1.4 0.13 12.0 0.0 2.1 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) VSP PF03302.13 KPA43556.1 - 0.002 17.1 0.5 0.0033 16.3 0.5 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF5536 PF17688.1 KPA43556.1 - 0.02 14.8 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5536) Cupredoxin_1 PF13473.6 KPA43556.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain Serglycin PF04360.12 KPA43556.1 - 0.81 9.6 3.5 1.9 8.4 3.5 1.6 1 0 0 1 1 1 0 Serglycin Alg6_Alg8 PF03155.15 KPA43557.1 - 9e-127 424.0 30.2 5.6e-80 269.6 12.9 2.2 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family BRO1 PF03097.18 KPA43558.1 - 1.2e-07 30.9 0.0 1.5e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Fer2_3 PF13085.6 KPA43560.1 - 6.4e-33 113.0 0.0 1e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 KPA43560.1 - 5.5e-09 36.3 9.4 6.9e-07 29.6 10.7 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KPA43560.1 - 1e-08 35.5 6.7 1e-08 35.5 6.7 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KPA43560.1 - 1.7e-08 34.4 3.1 1.7e-08 34.4 3.1 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KPA43560.1 - 0.0025 17.7 0.3 0.0025 17.7 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 KPA43560.1 - 0.0051 17.0 0.4 0.31 11.3 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KPA43560.1 - 0.0068 17.0 5.7 0.0068 17.0 5.7 2.4 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KPA43560.1 - 0.54 11.2 10.5 1.4 9.9 1.3 3.0 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KPA43560.1 - 0.64 10.2 14.0 2.9 8.1 11.0 2.9 2 1 2 4 4 4 0 4Fe-4S dicluster domain SpoIIE PF07228.12 KPA43561.1 - 7.9e-12 45.5 0.2 5.3e-11 42.8 0.1 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KPA43561.1 - 2.1e-07 30.8 1.1 4e-07 29.9 0.9 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KPA43561.1 - 5.6e-05 22.9 0.1 0.047 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Mito_carr PF00153.27 KPA43562.1 - 3.2e-47 158.4 6.0 6.4e-19 67.7 0.3 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2523 PF10734.9 KPA43562.1 - 0.05 14.2 0.0 0.16 12.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) Serine_protease PF18405.1 KPA43562.1 - 0.069 12.3 0.4 0.56 9.3 0.1 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease JAB PF01398.21 KPA43564.1 - 9.3e-10 38.5 0.5 1.6e-08 34.6 0.5 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Med2 PF11214.8 KPA43564.1 - 0.32 11.2 1.8 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 2 AdoHcyase PF05221.17 KPA43565.1 - 1.2e-128 428.4 0.0 6.5e-74 248.8 0.4 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KPA43565.1 - 6.3e-84 279.9 1.7 9.5e-84 279.4 1.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KPA43565.1 - 7.9e-07 28.6 0.2 1.6e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KPA43565.1 - 0.013 15.1 0.3 0.024 14.2 0.3 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 KPA43565.1 - 0.025 14.3 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 KPA43565.1 - 0.067 13.5 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KPA43566.1 - 1e-54 184.6 0.0 3.6e-54 182.8 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPA43566.1 - 5.3e-18 65.0 0.0 6.4e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KPA43566.1 - 0.0032 17.6 0.0 0.0054 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Gln-synt_C-ter PF18318.1 KPA43566.1 - 0.14 12.1 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 Glutamine synthetase C-terminal domain DUF1640 PF07798.11 KPA43567.1 - 1.9e-54 184.4 8.9 2.3e-54 184.1 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Phage_coat PF09063.10 KPA43567.1 - 0.0088 16.0 0.1 2 8.5 0.1 2.5 1 1 1 2 2 2 2 Phage PP7 coat protein GNAT_acetyltr_2 PF13718.6 KPA43567.1 - 0.021 14.2 1.1 0.077 12.4 0.0 1.9 1 1 1 2 2 2 0 GNAT acetyltransferase 2 cwf21 PF08312.12 KPA43567.1 - 0.097 12.8 3.9 0.081 13.1 1.9 1.9 2 0 0 2 2 2 0 cwf21 domain HU-CCDC81_bac_2 PF18175.1 KPA43567.1 - 0.34 10.8 2.1 2 8.3 0.6 2.5 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 Metal_resist PF13801.6 KPA43567.1 - 3.4 7.9 7.7 0.36 11.0 2.4 2.0 2 0 0 2 2 2 0 Heavy-metal resistance MFS_1 PF07690.16 KPA43569.1 - 1.7e-43 148.9 44.3 3.4e-43 147.9 44.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2196 PF09962.9 KPA43569.1 - 1.3e-23 82.7 3.0 2.5e-23 81.8 3.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) TRI12 PF06609.13 KPA43569.1 - 4.7e-11 41.8 23.3 1.2e-10 40.5 23.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPA43569.1 - 9.7e-11 41.2 5.5 9.7e-11 41.2 5.5 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KPA43569.1 - 0.0024 16.2 1.3 0.0024 16.2 1.3 3.2 2 2 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family zf-Di19 PF05605.12 KPA43569.1 - 0.0087 16.3 0.6 0.016 15.5 0.6 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Clathrin PF00637.20 KPA43570.1 - 3.4e-202 662.4 41.7 9.4e-33 113.1 1.0 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KPA43570.1 - 7.1e-34 114.5 0.2 6.6e-07 29.3 0.1 6.6 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin_H_link PF13838.6 KPA43570.1 - 1e-29 102.2 2.2 4.1e-29 100.3 0.2 3.1 3 0 0 3 3 3 1 Clathrin-H-link TPR_14 PF13428.6 KPA43570.1 - 1.6e-06 28.4 8.3 8.1 7.6 0.0 8.6 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPA43570.1 - 3.7e-05 23.4 4.4 8.3 6.7 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KPA43570.1 - 0.0012 18.5 1.6 1.1 9.2 0.0 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA43570.1 - 0.0014 18.7 8.4 0.049 13.9 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPA43570.1 - 0.014 15.7 4.4 6.2 7.2 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat 6PF2K PF01591.18 KPA43570.1 - 0.02 14.2 0.8 0.062 12.6 0.1 2.2 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Coatomer_WDAD PF04053.14 KPA43570.1 - 0.025 13.7 10.3 0.12 11.4 0.2 4.7 5 0 0 5 5 5 0 Coatomer WD associated region TPR_2 PF07719.17 KPA43570.1 - 0.036 14.2 7.0 0.83 9.9 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Clathrin-link PF09268.10 KPA43570.1 - 0.095 12.1 0.2 0.24 10.8 0.2 1.8 1 0 0 1 1 1 0 Clathrin, heavy-chain linker TPR_19 PF14559.6 KPA43570.1 - 0.68 10.5 9.7 14 6.3 0.1 6.4 6 1 0 7 7 6 0 Tetratricopeptide repeat YbjQ_1 PF01906.17 KPA43571.1 - 2.9e-26 92.1 0.5 3.7e-26 91.8 0.5 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding DPPIV_N PF00930.21 KPA43572.1 - 9.7e-112 373.2 0.2 1.3e-111 372.8 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KPA43572.1 - 5.8e-53 179.5 1.1 5.8e-53 179.5 1.1 2.2 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KPA43572.1 - 0.0007 20.3 1.9 0.037 14.6 1.0 2.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KPA43572.1 - 0.0017 18.0 0.9 0.0094 15.6 0.5 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KPA43572.1 - 0.096 12.3 0.5 0.23 11.1 0.0 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF5050 PF16472.5 KPA43572.1 - 0.11 11.8 0.0 0.3 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) Trehalase PF01204.18 KPA43573.1 - 2.4e-118 396.2 4.9 1.8e-117 393.3 4.9 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 KPA43573.1 - 7.5e-05 21.8 0.6 0.00013 21.1 0.2 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Beta_elim_lyase PF01212.21 KPA43574.1 - 2.6e-74 250.2 0.0 3.1e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KPA43574.1 - 0.049 12.6 0.0 0.071 12.0 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KPA43574.1 - 0.065 12.5 0.0 0.15 11.3 0.0 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KPA43574.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_transf_17 PF04724.13 KPA43575.1 - 1.1e-51 176.0 0.1 1.1e-50 172.7 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 17 Arf PF00025.21 KPA43576.1 - 7.1e-41 139.5 0.0 7.9e-41 139.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KPA43576.1 - 6.3e-19 68.1 0.0 7.2e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA43576.1 - 3.2e-15 56.4 0.0 4.4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KPA43576.1 - 1.7e-06 27.6 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KPA43576.1 - 2.5e-06 27.0 0.0 3.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPA43576.1 - 3.6e-06 27.0 0.0 5.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KPA43576.1 - 4.1e-05 22.9 0.1 9.4e-05 21.7 0.1 1.8 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 KPA43576.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 KPA43576.1 - 0.19 11.8 0.0 1.1 9.3 0.1 1.9 1 1 1 2 2 2 0 Dynamin family RNA_pol_Rpb2_6 PF00562.28 KPA43577.1 - 1e-111 373.8 0.0 1.4e-111 373.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KPA43577.1 - 2.8e-34 118.4 0.0 4.5e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KPA43577.1 - 5.8e-28 96.9 0.0 1.4e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KPA43577.1 - 1.5e-23 83.4 0.0 3.5e-23 82.2 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 KPA43577.1 - 2.7e-23 81.7 0.0 6e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KPA43577.1 - 4.6e-16 59.0 0.0 1.2e-14 54.5 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 DUF570 PF04489.13 KPA43577.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF570) Tyrosinase PF00264.20 KPA43578.1 - 2.3e-50 171.9 3.1 2.3e-50 171.9 3.1 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KPA43578.1 - 0.00032 21.3 0.0 0.00098 19.8 0.0 1.8 1 1 0 1 1 1 1 Tyosinase C-terminal domain DUF4384 PF14326.6 KPA43578.1 - 0.054 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) zf-C2H2_4 PF13894.6 KPA43579.1 - 0.23 12.4 2.7 14 6.8 0.3 3.0 1 1 1 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA43579.1 - 0.27 11.8 0.2 0.27 11.8 0.2 3.1 2 1 1 3 3 3 0 Zinc finger, C2H2 type ADC PF06314.11 KPA43580.1 - 0.00032 20.3 0.0 0.00072 19.2 0.0 1.5 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Cyclin PF08613.11 KPA43581.1 - 2.7e-40 138.4 3.0 4e-24 85.8 0.0 3.4 3 2 0 3 3 3 2 Cyclin DUF913 PF06025.12 KPA43581.1 - 0.012 14.6 0.1 0.012 14.6 0.1 2.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) GCIP PF13324.6 KPA43581.1 - 0.032 13.8 0.2 0.066 12.8 0.2 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Fib_alpha PF08702.10 KPA43581.1 - 0.036 14.2 0.4 0.036 14.2 0.4 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Proteasome PF00227.26 KPA43582.1 - 3.1e-46 157.3 0.1 3.9e-46 157.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Evr1_Alr PF04777.13 KPA43583.1 - 6.7e-27 93.9 0.3 9.7e-27 93.4 0.3 1.2 1 0 0 1 1 1 1 Erv1 / Alr family McrBC PF10117.9 KPA43583.1 - 0.036 13.2 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component SNAD4 PF18750.1 KPA43583.1 - 0.041 14.0 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC1 PF18769.1 KPA43583.1 - 0.092 13.0 0.0 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 APOBEC1 LmjF365940-deam PF14421.6 KPA43583.1 - 0.16 11.6 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases DUF3433 PF11915.8 KPA43585.1 - 1.6e-36 124.6 10.3 4.9e-20 71.8 2.3 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) DUF3382 PF11862.8 KPA43585.1 - 3.3 8.0 6.9 1.6 9.0 0.7 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3382) PHP PF02811.19 KPA43586.1 - 3.8e-14 53.3 0.0 5.1e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 PHP domain Hist_deacetyl PF00850.19 KPA43587.1 - 1.1e-51 176.1 0.1 2.2e-51 175.2 0.1 1.5 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 KPA43587.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 RTP801 C-terminal region RP-C_C PF11800.8 KPA43588.1 - 0.23 11.5 1.8 0.17 11.9 0.3 1.5 2 0 0 2 2 2 0 Replication protein C C-terminal region MID_MedPIWI PF18296.1 KPA43588.1 - 0.56 10.0 10.0 0.68 9.7 5.7 2.1 2 0 0 2 2 2 0 MID domain of medPIWI Pex14_N PF04695.13 KPA43588.1 - 2 9.0 5.9 3.9 8.1 1.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serglycin PF04360.12 KPA43588.1 - 9 6.2 10.8 0.2 11.6 2.9 2.1 2 0 0 2 2 2 0 Serglycin TGT PF01702.18 KPA43589.1 - 4.7e-141 470.0 0.0 5.5e-141 469.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase ATG22 PF11700.8 KPA43590.1 - 1.7e-196 653.5 13.2 2e-196 653.3 13.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF3602 PF12223.8 KPA43591.1 - 5.6e-23 81.3 13.8 1.4e-22 80.0 5.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Lipase_GDSL_2 PF13472.6 KPA43592.1 - 3.2e-15 57.0 0.1 2e-14 54.4 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA43592.1 - 2.3e-06 27.7 0.0 0.0024 17.9 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CHORD PF04968.12 KPA43593.1 - 1.9e-49 166.2 22.0 1.9e-25 89.3 6.9 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 KPA43593.1 - 4.7e-12 46.7 0.0 7.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.14 KPA43594.1 - 2.9e-13 50.0 0.0 3.4e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KPA43594.1 - 2.4e-05 24.5 0.2 4.7e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 KPA43594.1 - 0.013 15.3 0.3 0.05 13.4 0.0 1.8 1 1 1 2 2 2 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KPA43594.1 - 0.073 13.5 0.1 0.14 12.6 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain HpcH_HpaI PF03328.14 KPA43595.1 - 6.8e-31 107.1 0.0 9.1e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SHS2_Rpb7-N PF03876.17 KPA43596.1 - 2.8e-13 50.0 0.0 4.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KPA43596.1 - 1.8e-11 44.2 0.0 3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.11 KPA43597.1 - 1.4e-26 92.4 2.3 2.1e-26 91.9 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) TctB PF07331.11 KPA43597.1 - 1.4 9.2 9.3 0.13 12.6 5.0 1.6 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family CPSase_L_D2 PF02786.17 KPA43599.1 - 1.1e-108 361.6 0.0 7.7e-84 280.4 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KPA43599.1 - 9.9e-42 142.2 0.1 3.1e-41 140.5 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KPA43599.1 - 1.3e-21 76.9 0.3 2.5e-10 40.2 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KPA43599.1 - 4.8e-20 72.0 0.8 1.8e-09 37.4 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KPA43599.1 - 3.2e-11 43.1 0.0 0.0003 20.5 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 KPA43599.1 - 7.7e-06 25.8 0.3 0.06 13.1 0.1 2.9 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 KPA43599.1 - 3.4e-05 23.4 0.1 0.044 13.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 KPA43599.1 - 3.5e-05 23.9 0.2 0.24 11.4 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain NPL4 PF05021.15 KPA43600.1 - 5.2e-140 466.1 0.0 8.5e-140 465.4 0.0 1.3 2 0 0 2 2 2 1 NPL4 family zf-NPL4 PF05020.15 KPA43600.1 - 3.9e-66 221.7 0.0 6.9e-66 220.9 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KPA43600.1 - 0.00019 21.8 0.0 0.00052 20.4 0.0 1.8 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 KPA43601.1 - 5.3e-79 264.0 0.5 6.2e-79 263.8 0.5 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 KPA43601.1 - 0.0084 16.2 0.1 0.063 13.4 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3848) PEP-utilisers_N PF05524.13 KPA43601.1 - 0.025 14.7 3.8 0.034 14.3 2.8 1.6 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal LPD30 PF18850.1 KPA43601.1 - 0.052 13.3 1.3 2.7 7.8 1.0 2.2 2 0 0 2 2 2 0 Large polyvalent protein associated domain 30 CPL PF08144.11 KPA43601.1 - 0.12 12.8 0.3 0.34 11.2 0.2 1.7 2 0 0 2 2 2 0 CPL (NUC119) domain Rax2 PF12768.7 KPA43601.1 - 0.86 9.0 3.3 18 4.7 0.1 2.1 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DUF3294 PF07957.11 KPA43602.1 - 0.22 11.2 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) ORC3_N PF07034.11 KPA43603.1 - 8.6e-38 130.3 2.7 5.1e-36 124.4 2.7 2.3 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KPA43603.1 - 1.7e-25 89.7 5.6 4.6e-16 59.2 0.0 3.1 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal PWWP PF00855.17 KPA43604.1 - 1.4e-16 60.7 1.7 1.1e-15 57.8 0.0 3.0 1 1 1 2 2 2 1 PWWP domain Med26 PF08711.11 KPA43604.1 - 0.0012 18.8 1.6 0.0029 17.6 1.6 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Sec63 PF02889.16 KPA43605.1 - 3.4e-165 547.4 0.3 1.2e-93 313.0 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KPA43605.1 - 5.9e-51 172.7 0.1 5.5e-28 97.9 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KPA43605.1 - 2.9e-33 114.3 0.2 2.9e-33 114.3 0.2 2.1 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 KPA43605.1 - 4.7e-24 85.3 0.0 2.7e-12 47.0 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPA43605.1 - 6.4e-11 42.6 0.0 5.2e-08 33.2 0.0 3.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KPA43605.1 - 1.2e-06 28.9 0.7 0.1 12.9 0.0 3.4 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 KPA43605.1 - 0.00074 18.7 0.0 1.2 8.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 KPA43605.1 - 0.01 16.1 0.6 17 5.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 KPA43605.1 - 0.012 15.0 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.21 KPA43605.1 - 0.029 13.9 0.1 5.3 6.5 0.0 3.0 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain YjcZ PF13990.6 KPA43606.1 - 0.13 11.6 0.1 0.13 11.6 0.1 2.6 4 0 0 4 4 4 0 YjcZ-like protein Exonuc_VII_S PF02609.16 KPA43606.1 - 0.18 11.9 3.4 0.15 12.1 0.7 2.2 2 0 0 2 2 2 0 Exonuclease VII small subunit Hep_59 PF07052.11 KPA43606.1 - 0.58 10.9 0.1 0.58 10.9 0.1 3.9 4 0 0 4 4 4 0 Hepatocellular carcinoma-associated antigen 59 FAM76 PF16046.5 KPA43606.1 - 0.7 9.2 11.2 0.77 9.1 4.2 2.4 2 1 0 2 2 2 0 FAM76 protein Rep_fac_C PF08542.11 KPA43607.1 - 2.4e-20 72.7 0.0 5.5e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KPA43607.1 - 1.1e-16 61.5 0.0 5.4e-16 59.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KPA43607.1 - 8.1e-13 48.5 0.0 6.2e-11 42.3 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KPA43607.1 - 6.2e-09 36.0 0.0 1.9e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 KPA43607.1 - 7e-06 25.9 0.0 2.5e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPA43607.1 - 7.8e-06 26.4 0.0 0.00043 20.7 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 KPA43607.1 - 5.2e-05 23.2 0.1 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KPA43607.1 - 7.5e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 KPA43607.1 - 8e-05 22.9 0.1 0.00028 21.2 0.1 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 KPA43607.1 - 0.00012 22.3 0.1 0.0096 16.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KPA43607.1 - 0.00085 19.4 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KPA43607.1 - 0.00098 18.6 0.0 0.053 12.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KPA43607.1 - 0.0042 16.3 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KPA43607.1 - 0.006 16.3 0.0 0.02 14.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KPA43607.1 - 0.0071 16.3 0.2 0.093 12.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KPA43607.1 - 0.0089 16.4 0.0 0.062 13.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KPA43607.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KPA43607.1 - 0.021 14.5 0.0 0.067 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KPA43607.1 - 0.024 13.9 0.0 0.064 12.5 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KPA43607.1 - 0.034 14.2 0.0 0.24 11.4 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KPA43607.1 - 0.047 13.9 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPA43607.1 - 0.047 14.2 0.0 0.14 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KPA43607.1 - 0.063 12.7 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 KPA43607.1 - 0.073 12.9 0.0 0.36 10.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KPA43607.1 - 0.077 13.2 0.0 0.28 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPA43607.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.29 KPA43607.1 - 0.11 12.2 0.0 0.98 9.2 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase UQ_con PF00179.26 KPA43608.1 - 1e-40 138.7 0.1 2.8e-27 95.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme DUF2417 PF10329.9 KPA43611.1 - 1.1e-83 280.3 4.3 1.4e-83 280.0 4.3 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) RhoGAP PF00620.27 KPA43612.1 - 1.8e-34 118.7 0.0 3.8e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KPA43612.1 - 3.3e-30 104.1 38.4 1.2e-11 44.6 5.8 5.0 5 0 0 5 5 5 4 LIM domain zf-dskA_traR PF01258.17 KPA43612.1 - 0.3 11.0 8.4 7.6 6.6 0.0 3.9 2 1 1 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger 3Beta_HSD PF01073.19 KPA43613.1 - 1.9e-68 230.5 0.0 2.5e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPA43613.1 - 2.6e-32 112.2 0.3 4.5e-32 111.4 0.1 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KPA43613.1 - 3.7e-16 59.1 0.2 5.3e-16 58.6 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KPA43613.1 - 1.9e-15 56.8 0.1 1.3e-11 44.1 0.1 2.1 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KPA43613.1 - 3e-15 56.5 0.1 8.6e-14 51.7 0.1 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KPA43613.1 - 1e-13 51.6 0.1 1.4e-13 51.1 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KPA43613.1 - 1.1e-08 34.6 0.5 1.5e-07 30.9 0.7 2.6 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein KR PF08659.10 KPA43613.1 - 0.0035 17.3 0.6 0.051 13.5 0.6 2.4 1 1 0 1 1 1 1 KR domain COQ9 PF08511.11 KPA43613.1 - 0.013 15.2 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 COQ9 DapB_N PF01113.20 KPA43613.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HMG_box_2 PF09011.10 KPA43615.1 - 7.7e-09 36.0 4.0 4.7e-08 33.5 4.0 2.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KPA43615.1 - 1.7e-08 34.7 4.7 1.7e-08 34.7 4.7 2.8 3 1 0 3 3 3 1 HMG (high mobility group) box Prok-TraM PF09228.10 KPA43615.1 - 0.03 14.7 3.6 0.46 10.9 0.0 2.9 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM LGFP PF08310.11 KPA43615.1 - 0.15 12.6 0.0 0.32 11.6 0.0 1.6 1 0 0 1 1 1 0 LGFP repeat Proteasome PF00227.26 KPA43616.1 - 2.2e-30 105.6 0.0 2.6e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit SIS PF01380.22 KPA43617.1 - 1.6e-59 199.4 0.1 6.6e-32 110.1 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KPA43617.1 - 1.1e-17 64.5 0.0 2.2e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KPA43617.1 - 2.6e-10 40.3 0.0 6.1e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KPA43617.1 - 0.0003 19.8 0.0 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AAA PF00004.29 KPA43618.1 - 7e-43 146.2 0.0 1.2e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KPA43618.1 - 2.7e-12 46.4 0.1 9.3e-11 41.5 0.1 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KPA43618.1 - 1.6e-10 40.6 0.0 3.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KPA43618.1 - 1.3e-07 32.2 0.0 6.7e-05 23.3 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KPA43618.1 - 1.9e-06 27.9 0.1 3.8e-05 23.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KPA43618.1 - 2.3e-06 27.8 0.0 9.2e-06 25.9 0.0 2.0 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KPA43618.1 - 6.9e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KPA43618.1 - 0.00023 21.4 0.1 0.006 16.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KPA43618.1 - 0.0003 20.0 0.0 0.00076 18.7 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KPA43618.1 - 0.00035 21.1 0.1 0.0023 18.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KPA43618.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KPA43618.1 - 0.0021 17.3 0.0 0.0043 16.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KPA43618.1 - 0.0035 17.3 0.1 0.0097 15.9 0.0 1.7 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KPA43618.1 - 0.0036 16.7 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KPA43618.1 - 0.0045 17.2 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KPA43618.1 - 0.0052 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KPA43618.1 - 0.0059 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KPA43618.1 - 0.0066 16.5 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KPA43618.1 - 0.0083 15.8 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_11 PF13086.6 KPA43618.1 - 0.011 15.6 0.8 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPA43618.1 - 0.012 15.3 0.0 0.057 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KPA43618.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) eIF-1a PF01176.19 KPA43618.1 - 0.025 14.4 0.1 0.048 13.5 0.1 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Prot_ATP_OB_N PF17758.1 KPA43618.1 - 0.027 14.1 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_30 PF13604.6 KPA43618.1 - 0.036 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KPA43618.1 - 0.056 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 KPA43618.1 - 0.058 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KPA43618.1 - 0.091 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KPA43618.1 - 0.095 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KPA43618.1 - 0.1 11.9 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 KPA43618.1 - 0.1 11.9 2.9 0.13 11.5 0.0 2.5 4 0 0 4 4 3 0 KaiC Parvo_NS1 PF01057.17 KPA43618.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 KPA43618.1 - 0.42 11.1 4.1 7.7 7.0 0.7 2.6 2 1 0 2 2 2 0 AAA domain DUF4200 PF13863.6 KPA43618.1 - 1.4 9.3 8.2 0.17 12.3 3.6 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) OmpH PF03938.14 KPA43618.1 - 2.4 8.5 6.2 1.7 9.0 2.0 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Mago-bind PF09282.10 KPA43619.1 - 9.6e-13 47.8 2.3 2.1e-12 46.6 2.3 1.6 1 0 0 1 1 1 1 Mago binding Cation_ATPase_C PF00689.21 KPA43620.1 - 6.9e-31 107.4 0.2 6.9e-31 107.4 0.2 3.0 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KPA43620.1 - 1e-21 77.3 1.2 2.1e-21 76.3 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase UCR_UQCRX_QCR9 PF05365.12 KPA43620.1 - 1.4e-20 72.9 3.0 3.8e-20 71.6 3.0 1.8 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Cation_ATPase PF13246.6 KPA43620.1 - 5.7e-18 64.8 0.0 1.1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPA43620.1 - 4.5e-12 46.7 0.1 8.7e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPA43620.1 - 5.3e-06 26.0 0.1 2.2e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPA43620.1 - 0.00087 19.1 0.1 0.0018 18.1 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Abhydrolase_9_N PF15420.6 KPA43620.1 - 0.38 10.7 3.6 10 6.0 0.1 2.4 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Cyt_bd_oxida_II PF02322.15 KPA43620.1 - 1.4 8.2 7.0 12 5.1 7.1 2.2 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF4271 PF14093.6 KPA43620.1 - 5.8 6.8 9.1 6.4 6.6 0.0 3.9 4 1 1 5 5 5 0 Domain of unknown function (DUF4271) zf-UBR PF02207.20 KPA43621.1 - 3.4e-17 62.3 15.5 3.4e-17 62.3 15.5 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KPA43621.1 - 4.1e-06 26.5 0.0 9.2e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS RPN2_C PF18004.1 KPA43621.1 - 0.89 9.5 3.6 0.31 11.0 0.4 1.8 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CAP_N PF01213.19 KPA43621.1 - 2 7.8 5.5 5.9 6.3 5.5 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CRC_subunit PF08624.10 KPA43622.1 - 2.3e-54 183.5 0.0 4e-54 182.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit RR_TM4-6 PF06459.12 KPA43622.1 - 1.1 9.1 2.7 1.9 8.2 2.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lyase_1 PF00206.20 KPA43623.1 - 7.1e-86 288.4 0.0 9.4e-86 288.0 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KPA43623.1 - 7.2e-23 81.1 0.0 1.5e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Cyclin PF08613.11 KPA43625.1 - 6.6e-08 33.1 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin Mfp-3 PF04202.13 KPA43625.1 - 0.36 11.3 6.0 1 9.8 0.1 2.5 2 0 0 2 2 2 0 Foot protein 3 Nefa_Nip30_N PF10187.9 KPA43626.1 - 4e-24 85.0 14.4 3e-20 72.5 5.6 3.2 3 1 0 3 3 3 2 N-terminal domain of NEFA-interacting nuclear protein NIP30 Lyase_8 PF02278.18 KPA43626.1 - 0.052 13.0 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, super-sandwich domain Tim54 PF11711.8 KPA43627.1 - 2.4e-143 477.4 1.6 2.8e-143 477.2 1.6 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.25 KPA43628.1 - 4.9e-58 196.6 0.0 5.8e-57 193.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA43628.1 - 6.3e-27 94.5 0.2 9.9e-21 74.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KPA43628.1 - 5.8e-05 23.1 2.4 0.018 15.0 0.4 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KPA43628.1 - 8.7e-05 21.6 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KPA43628.1 - 0.00058 19.3 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KPA43628.1 - 0.0012 18.2 0.8 0.0027 17.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KPA43628.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KPA43628.1 - 0.59 9.7 2.2 0.87 9.1 0.0 2.0 2 0 0 2 2 2 0 RIO1 family SF3A2 PF16835.5 KPA43629.1 - 5.9e-34 116.3 0.2 9.3e-34 115.7 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KPA43629.1 - 3.7e-06 27.1 0.9 6.9e-06 26.3 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KPA43629.1 - 1.3e-05 25.1 0.3 1.9e-05 24.6 0.3 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 KPA43629.1 - 0.06 12.9 1.5 0.11 12.1 1.5 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Aminotran_3 PF00202.21 KPA43630.1 - 1.8e-50 171.8 1.3 1.4e-48 165.6 1.3 2.0 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KPA43630.1 - 0.0012 18.2 0.1 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KPA43630.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KPA43630.1 - 0.085 12.0 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II GidB PF02527.15 KPA43630.1 - 0.4 10.0 0.9 10 5.4 0.0 2.2 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G GN3L_Grn1 PF08701.11 KPA43631.1 - 4e-23 81.3 15.8 9.6e-23 80.1 15.8 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KPA43631.1 - 1.1e-17 64.1 0.1 8.8e-13 48.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPA43631.1 - 1.2e-07 31.5 0.0 0.0029 17.2 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPA43631.1 - 4.1e-07 30.0 0.2 3e-06 27.2 0.2 2.1 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KPA43631.1 - 0.0005 19.6 0.3 0.045 13.3 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KPA43631.1 - 0.00078 19.5 7.3 0.42 10.6 0.1 3.7 3 2 1 4 4 4 2 Dynamin family cobW PF02492.19 KPA43631.1 - 0.023 14.3 0.1 0.47 10.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KPA43631.1 - 0.028 13.4 0.1 0.028 13.4 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4632 PF15451.6 KPA43631.1 - 0.064 13.3 0.2 0.2 11.7 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Nuc_deoxyri_tr2 PF15891.5 KPA43631.1 - 0.072 13.4 0.1 0.43 10.9 0.0 2.3 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like ORC3_N PF07034.11 KPA43631.1 - 0.085 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Roc PF08477.13 KPA43631.1 - 0.15 12.2 0.1 20 5.4 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KPA43631.1 - 0.24 11.8 0.1 0.24 11.8 0.1 2.8 2 1 0 2 2 1 0 AAA ATPase domain NOA36 PF06524.12 KPA43631.1 - 2.5 7.4 13.6 4.3 6.6 13.6 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4407 PF14362.6 KPA43631.1 - 9.8 5.4 9.4 16 4.7 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNB PF00773.19 KPA43632.1 - 2.4e-97 326.2 0.1 2.4e-97 326.2 0.1 1.5 2 0 0 2 2 2 1 RNB domain Rrp44_S1 PF17215.3 KPA43632.1 - 2.8e-31 107.3 0.1 8.6e-31 105.8 0.1 1.9 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KPA43632.1 - 2.1e-28 98.9 0.1 6.1e-28 97.4 0.1 1.8 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KPA43632.1 - 2.6e-19 69.0 0.0 7.9e-19 67.5 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KPA43632.1 - 1.6e-10 41.4 0.1 1.6e-10 41.4 0.1 2.5 4 0 0 4 4 4 1 PIN domain CSD2 PF17876.1 KPA43632.1 - 2.4e-05 24.4 0.0 0.025 14.8 0.0 3.0 2 0 0 2 2 2 2 Cold shock domain TcfC PF16967.5 KPA43632.1 - 0.033 13.7 0.0 0.72 9.4 0.0 2.6 2 0 0 2 2 2 0 E-set like domain Dis3l2_C_term PF17877.1 KPA43632.1 - 0.058 13.7 1.3 0.12 12.8 0.0 2.3 2 0 0 2 2 2 0 DIS3-like exonuclease 2 C terminal CRC_subunit PF08624.10 KPA43633.1 - 4.4e-52 176.1 0.1 6.1e-52 175.6 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CBFD_NFYB_HMF PF00808.23 KPA43634.1 - 5.5e-09 36.2 0.1 1.3e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KPA43634.1 - 3.1e-08 34.0 0.6 3.1e-08 34.0 0.6 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KPA43634.1 - 0.0063 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Barttin PF15462.6 KPA43634.1 - 0.52 10.0 7.3 0.051 13.4 0.4 2.2 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) SUIM_assoc PF16619.5 KPA43635.1 - 3.6e-05 23.7 7.1 3.6e-05 23.7 7.1 1.9 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Roughex PF06020.11 KPA43635.1 - 0.0011 18.1 3.1 0.0015 17.7 3.1 1.1 1 0 0 1 1 1 1 Drosophila roughex protein DUF4448 PF14610.6 KPA43635.1 - 0.34 10.7 2.5 1.6 8.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Spt20 PF12090.8 KPA43635.1 - 0.35 10.5 10.8 0.51 9.9 10.8 1.2 1 0 0 1 1 1 0 Spt20 family DFRP_C PF16543.5 KPA43635.1 - 2 8.9 8.1 6.7 7.3 7.6 2.0 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Neur_chan_memb PF02932.16 KPA43635.1 - 3 7.8 7.3 4.1 7.4 7.3 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Amidoligase_2 PF12224.8 KPA43636.1 - 1.9e-20 73.6 0.0 3.5e-18 66.2 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme Sporozoite_P67 PF05642.11 KPA43637.1 - 0.28 9.2 7.6 0.34 8.9 7.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen F-box PF00646.33 KPA43638.1 - 0.055 13.4 0.8 0.49 10.3 0.4 2.8 3 0 0 3 3 3 0 F-box domain Cys_Met_Meta_PP PF01053.20 KPA43639.1 - 4.6e-139 463.2 0.1 5.2e-139 463.0 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KPA43639.1 - 9e-07 28.4 0.2 1.4e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPA43639.1 - 1.3e-06 27.7 0.4 2.4e-06 26.8 0.4 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KPA43639.1 - 6.7e-06 25.6 0.5 1.4e-05 24.6 0.5 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 KPA43639.1 - 0.0093 14.8 0.1 0.014 14.3 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein 2-Hacid_dh PF00389.30 KPA43639.1 - 0.014 15.0 0.1 0.032 13.9 0.1 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Zn_clus PF00172.18 KPA43640.1 - 2.8e-08 33.7 10.3 4.3e-08 33.1 10.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA43640.1 - 8.7e-07 28.1 0.0 1.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-PARP PF00645.18 KPA43640.1 - 9.5 7.2 8.0 11 7.0 4.5 2.6 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Brix PF04427.18 KPA43641.1 - 8e-45 153.3 0.0 1.1e-44 152.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain TPR_1 PF00515.28 KPA43642.1 - 1.6e-21 75.1 5.1 8.2e-07 28.6 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPA43642.1 - 1.6e-20 71.5 5.7 2.2e-06 27.4 0.2 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KPA43642.1 - 3.8e-17 61.5 6.8 4.3e-05 24.0 0.3 6.2 4 2 3 7 7 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KPA43642.1 - 5e-17 62.3 7.0 5.2e-06 27.0 0.9 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 KPA43642.1 - 4.3e-15 55.1 7.5 1.3e-06 28.0 0.1 4.9 3 2 2 5 5 5 3 TPR repeat TPR_19 PF14559.6 KPA43642.1 - 5.4e-15 55.6 6.7 0.00033 21.1 1.3 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KPA43642.1 - 3.7e-12 45.4 1.2 0.00011 22.1 0.1 5.2 7 0 0 7 7 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPA43642.1 - 6.5e-12 45.0 4.4 0.069 13.6 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KPA43642.1 - 3e-09 36.2 5.1 0.021 14.8 0.2 5.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KPA43642.1 - 1.1e-08 35.2 7.0 0.13 13.0 0.2 6.2 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KPA43642.1 - 1.2e-08 35.1 11.1 8.5e-06 26.0 0.9 4.7 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_20 PF14561.6 KPA43642.1 - 6.6e-08 32.8 4.8 0.0039 17.5 0.2 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KPA43642.1 - 5.1e-06 26.5 8.1 0.0073 16.4 0.2 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 KPA43642.1 - 3.2e-05 23.3 4.2 0.072 12.3 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 KPA43642.1 - 0.012 15.6 0.1 6.3 6.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4919 PF16266.5 KPA43642.1 - 0.027 14.4 0.1 0.18 11.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) DUF484 PF04340.12 KPA43642.1 - 0.03 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF484 ANAPC3 PF12895.7 KPA43642.1 - 0.045 14.0 10.2 0.46 10.7 0.3 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KPA43642.1 - 0.048 13.7 1.0 28 4.9 0.1 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain NatB_MDM20 PF09797.9 KPA43642.1 - 0.062 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF1641 PF07849.11 KPA43642.1 - 0.11 12.4 0.2 0.25 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_10 PF13374.6 KPA43642.1 - 0.38 10.7 9.6 0.11 12.4 1.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat HLH PF00010.26 KPA43643.1 - 6.7e-12 45.2 1.1 6.7e-12 45.2 1.1 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain NRBF2 PF08961.10 KPA43643.1 - 1.8e-05 24.4 1.0 3.4e-05 23.5 1.0 1.4 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator DUF4776 PF16003.5 KPA43643.1 - 0.021 13.9 0.4 0.032 13.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) TMEM219 PF14940.6 KPA43643.1 - 0.089 12.4 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Transmembrane 219 ZapB PF06005.12 KPA43643.1 - 2.6 8.5 6.8 1.1 9.8 3.1 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Ceramidase PF05875.12 KPA43645.1 - 1.7e-71 240.8 2.2 2e-71 240.5 2.2 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 KPA43645.1 - 0.094 12.7 1.7 0.23 11.5 1.7 1.6 1 0 0 1 1 1 0 Trp-operon Leader Peptide GMC_oxred_N PF00732.19 KPA43646.1 - 1.5e-30 106.7 0.0 6.7e-19 68.4 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA43646.1 - 9.1e-30 104.1 0.0 1.8e-29 103.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KPA43646.1 - 2e-05 24.0 0.0 3.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA43646.1 - 0.00073 19.7 0.0 0.0023 18.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPA43646.1 - 0.0026 16.9 0.1 0.0051 16.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KPA43646.1 - 0.0067 15.5 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KPA43646.1 - 0.0074 15.6 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KPA43646.1 - 0.031 13.5 0.0 0.65 9.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA43646.1 - 0.13 11.8 0.8 0.2 11.2 0.8 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA43646.1 - 0.15 10.7 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Coat_F PF07875.12 KPA43646.1 - 0.16 12.2 0.2 0.46 10.8 0.2 1.7 1 0 0 1 1 1 0 Coat F domain FAD_oxidored PF12831.7 KPA43646.1 - 0.18 11.1 0.0 0.42 9.9 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.25 KPA43647.1 - 5.4e-18 65.1 0.0 4e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA43647.1 - 2e-12 47.2 0.0 2.8e-10 40.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA43647.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF3425 PF11905.8 KPA43648.1 - 2.8e-16 59.6 0.1 1.6e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Selenoprotein_S PF06936.11 KPA43648.1 - 0.041 13.7 1.2 0.062 13.1 1.2 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) LRR_8 PF13855.6 KPA43649.1 - 4.7e-27 93.5 52.6 3.2e-07 30.0 2.8 8.6 4 2 4 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 KPA43649.1 - 4.7e-26 90.4 50.8 4.8e-05 23.6 1.3 10.0 7 2 4 11 11 11 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KPA43649.1 - 0.0065 16.4 34.5 0.49 10.6 1.5 10.5 12 0 0 12 12 12 2 Leucine Rich repeat LRR_9 PF14580.6 KPA43649.1 - 0.0094 15.5 2.2 0.0094 15.5 2.2 5.4 4 2 3 7 7 7 3 Leucine-rich repeat DUF2207 PF09972.9 KPA43650.1 - 0.11 11.3 0.5 0.12 11.2 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cep57_CLD_2 PF14197.6 KPA43651.1 - 0.018 15.1 5.0 0.018 15.1 5.0 3.2 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Ribosomal_S2 PF00318.20 KPA43651.1 - 0.031 13.5 0.9 0.061 12.6 0.9 1.4 1 0 0 1 1 1 0 Ribosomal protein S2 Thiolase_N PF00108.23 KPA43652.1 - 1.7e-67 227.6 2.4 2.6e-67 226.9 2.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPA43652.1 - 6.1e-43 145.4 1.3 1e-42 144.7 0.2 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KPA43652.1 - 7.3e-05 22.5 1.4 0.00016 21.3 1.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KPA43652.1 - 0.043 13.7 1.3 0.56 10.1 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Peptidase_M35 PF02102.15 KPA43654.1 - 1.2e-75 254.7 7.1 1.4e-75 254.5 7.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KPA43654.1 - 8.8e-41 139.8 2.8 8.8e-41 139.8 2.8 1.9 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase Macoilin PF09726.9 KPA43655.1 - 0.17 10.4 0.9 0.26 9.8 0.9 1.2 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 KPA43655.1 - 4.1 6.9 22.2 2.3 7.8 18.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Chordopox_L2 PF05803.12 KPA43656.1 - 0.056 13.3 0.1 0.074 12.9 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus L2 protein SseC PF04888.12 KPA43656.1 - 0.74 9.3 7.3 0.46 10.0 5.6 1.5 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family SKG6 PF08693.10 KPA43657.1 - 3.7e-05 23.0 0.4 7.1e-05 22.1 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sigma_reg_N PF13800.6 KPA43659.1 - 3.9 7.8 0.0 3.9 7.8 0.0 3.6 4 1 0 4 4 4 0 Sigma factor regulator N-terminal 4HBT PF03061.22 KPA43660.1 - 1.8e-14 53.8 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KPA43660.1 - 0.00084 19.5 0.0 0.0013 18.8 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) SKG6 PF08693.10 KPA43661.1 - 1.2e-06 27.8 0.1 2.6e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KPA43661.1 - 0.045 13.7 0.2 0.065 13.1 0.2 1.2 1 0 0 1 1 1 0 TMEM154 protein family Mannosyl_trans3 PF11051.8 KPA43662.1 - 3.6e-42 144.6 0.0 1e-41 143.1 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative Tfb2 PF03849.14 KPA43663.1 - 2.6e-138 460.8 0.0 3.1e-138 460.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KPA43663.1 - 8.9e-21 74.1 0.3 1.9e-20 73.0 0.3 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KPA43663.1 - 0.00067 19.8 0.2 0.0017 18.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TANGO2 PF05742.12 KPA43665.1 - 9.9e-66 222.4 0.0 1.1e-65 222.2 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Occludin_ELL PF07303.13 KPA43666.1 - 0.0065 17.2 18.2 0.022 15.5 7.4 3.7 1 1 3 4 4 4 1 Occludin homology domain MAD PF05557.13 KPA43666.1 - 0.072 11.4 26.9 0.21 9.9 27.0 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein Rx_N PF18052.1 KPA43666.1 - 0.26 11.6 15.6 1.4 9.2 0.1 3.5 2 1 1 3 3 3 0 Rx N-terminal domain CALCOCO1 PF07888.11 KPA43666.1 - 0.32 9.8 23.5 0.52 9.1 20.9 2.0 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 KPA43666.1 - 0.46 9.3 26.3 0.3 9.9 16.8 2.3 1 1 2 3 3 3 0 Spc7 kinetochore protein APG6_N PF17675.1 KPA43666.1 - 1.1 9.8 33.1 4.4 7.8 5.8 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region CENP-H PF05837.12 KPA43666.1 - 2.7 8.4 26.0 1.1 9.7 8.6 3.4 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Hemerythrin PF01814.23 KPA43666.1 - 6 7.5 9.6 15 6.2 9.1 2.0 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain GAS PF13851.6 KPA43666.1 - 6.5 6.0 27.0 1.2 8.5 3.2 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KPA43666.1 - 7.8 6.5 28.7 3.2 7.8 10.1 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C4H2 PF10146.9 KPA43666.1 - 8 6.7 20.5 0.25 11.6 0.5 2.5 1 1 1 2 2 2 0 Zinc finger-containing protein Fez1 PF06818.15 KPA43666.1 - 8.9 6.7 25.5 4.3 7.7 14.3 2.5 1 1 1 2 2 2 0 Fez1 Methyltransf_16 PF10294.9 KPA43667.1 - 1.8e-23 83.1 0.0 2.9e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KPA43667.1 - 6.8e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA43667.1 - 0.05 13.1 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KPA43667.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KPA43667.1 - 0.11 13.3 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF5044 PF16447.5 KPA43667.1 - 0.17 11.7 0.0 0.57 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5044) HAD_2 PF13419.6 KPA43669.1 - 2.2e-21 76.7 0.0 2.8e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA43669.1 - 6.5e-10 39.6 0.0 1.4e-09 38.6 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPA43669.1 - 7.7e-08 33.0 0.2 1e-07 32.5 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA43669.1 - 0.026 14.6 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_6 PF13344.6 KPA43669.1 - 0.039 14.1 0.0 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Rop-like PF05082.13 KPA43669.1 - 0.17 11.8 0.2 4.9 7.1 0.1 2.4 2 1 0 2 2 2 0 Rop-like ABC2_membrane PF01061.24 KPA43670.1 - 1.1e-69 234.0 62.5 8.1e-36 123.4 27.1 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KPA43670.1 - 1.5e-34 119.4 0.0 6.5e-16 59.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KPA43670.1 - 2.6e-28 97.8 5.4 2e-23 82.1 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KPA43670.1 - 1.3e-17 64.1 0.0 4.6e-17 62.4 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 KPA43670.1 - 1.1e-06 28.8 0.0 0.0022 18.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KPA43670.1 - 1.5e-06 28.3 0.0 0.01 15.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KPA43670.1 - 1.7e-06 28.5 0.0 0.0085 16.5 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.6 KPA43670.1 - 1.8e-06 28.4 0.0 0.0062 17.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KPA43670.1 - 1.1e-05 26.0 0.0 0.014 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KPA43670.1 - 9e-05 22.1 0.1 0.0089 15.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KPA43670.1 - 0.0001 21.5 16.2 0.0001 21.5 16.2 2.7 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.6 KPA43670.1 - 0.00016 21.3 0.1 0.0078 15.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KPA43670.1 - 0.00032 21.0 0.0 0.062 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KPA43670.1 - 0.001 19.0 0.1 0.0063 16.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KPA43670.1 - 0.002 17.8 0.2 0.22 11.1 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KPA43670.1 - 0.0041 17.4 0.0 0.88 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KPA43670.1 - 0.0044 16.9 0.2 2.9 7.8 0.0 2.4 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.19 KPA43670.1 - 0.012 15.1 0.2 0.32 10.4 0.0 2.9 2 2 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KPA43670.1 - 0.032 14.0 0.1 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KPA43670.1 - 0.065 13.7 0.0 11 6.5 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KPA43670.1 - 0.073 12.4 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KPA43670.1 - 0.084 12.6 0.1 19 4.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KPA43670.1 - 0.099 13.0 0.0 9.8 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 KPA43670.1 - 0.12 12.8 0.2 0.49 10.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 KPA43670.1 - 0.15 12.1 0.8 6.5 6.8 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 KPA43670.1 - 0.15 11.8 0.3 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Guanylate_cyc_2 PF09778.9 KPA43670.1 - 0.18 11.1 0.1 0.41 10.0 0.1 1.5 1 0 0 1 1 1 0 Guanylylate cyclase ABC_tran PF00005.27 KPA43671.1 - 4.5e-38 130.9 0.0 2e-19 70.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 KPA43671.1 - 8e-27 94.6 29.6 5.1e-24 85.4 16.9 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KPA43671.1 - 4.4e-10 39.4 0.0 0.00064 19.2 0.2 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPA43671.1 - 5.9e-09 36.1 0.4 0.98 9.2 0.0 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KPA43671.1 - 1.8e-06 27.2 0.2 0.022 13.8 0.0 3.5 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_22 PF13401.6 KPA43671.1 - 1.9e-06 28.2 1.1 0.095 13.0 0.2 3.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KPA43671.1 - 0.00013 21.6 0.1 0.021 14.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KPA43671.1 - 0.00035 20.4 0.1 0.65 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KPA43671.1 - 0.0011 19.1 0.0 0.26 11.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KPA43671.1 - 0.0015 18.1 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KPA43671.1 - 0.0015 17.9 0.1 0.69 9.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_33 PF13671.6 KPA43671.1 - 0.0015 18.7 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KPA43671.1 - 0.0021 17.6 0.0 3.2 7.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KPA43671.1 - 0.0025 17.7 0.1 0.52 10.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 KPA43671.1 - 0.0034 17.5 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_23 PF13476.6 KPA43671.1 - 0.0044 17.5 0.4 0.53 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA43671.1 - 0.0048 17.3 0.1 2.6 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain TsaE PF02367.17 KPA43671.1 - 0.008 16.2 0.3 0.81 9.7 0.0 2.9 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KPA43671.1 - 0.0084 16.6 1.3 1.6 9.3 0.7 3.1 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KPA43671.1 - 0.028 14.5 0.9 2.6 8.1 0.2 2.6 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 KPA43671.1 - 0.037 13.8 0.2 1.6 8.4 0.3 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KPA43671.1 - 0.051 13.3 1.2 0.54 10.0 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.12 KPA43671.1 - 0.055 12.9 0.8 25 4.2 0.1 3.3 3 0 0 3 3 3 0 Poxvirus A32 protein Herpes_Helicase PF02689.14 KPA43671.1 - 0.078 10.9 0.0 0.15 9.9 0.0 1.4 1 0 0 1 1 1 0 Helicase NTPase_1 PF03266.15 KPA43671.1 - 0.13 12.1 0.9 3.4 7.6 0.0 2.7 3 0 0 3 3 2 0 NTPase MobB PF03205.14 KPA43671.1 - 0.14 12.1 0.2 23 4.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1656 PF07869.12 KPA43671.1 - 3.3 7.8 11.1 0.047 13.7 0.6 3.2 3 0 0 3 3 2 0 Protein of unknown function (DUF1656) FYVE_2 PF02318.16 KPA43672.1 - 0.02 15.1 3.8 0.036 14.3 3.8 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Methyltransf_23 PF13489.6 KPA43673.1 - 1.5e-22 80.2 0.0 2.7e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA43673.1 - 1e-12 48.7 0.0 2.8e-11 44.0 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA43673.1 - 1.4e-12 48.2 0.0 2.8e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA43673.1 - 2.4e-12 46.9 0.0 4.8e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA43673.1 - 4.1e-12 46.6 0.0 9.3e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA43673.1 - 2.7e-05 23.6 0.0 0.00017 21.0 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KPA43673.1 - 0.01 15.3 0.0 0.03 13.8 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase MetW PF07021.12 KPA43673.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 KPA43673.1 - 0.049 12.9 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 KPA43673.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 KPA43673.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KPA43673.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase WSC PF01822.19 KPA43674.1 - 5.5e-11 42.5 9.0 5.5e-11 42.5 9.0 2.7 2 1 0 2 2 2 1 WSC domain Meth_synt_2 PF01717.18 KPA43675.1 - 5.5e-16 58.7 0.0 1.5e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KPA43675.1 - 7.8e-07 28.9 0.0 0.001 18.6 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain ABC2_membrane PF01061.24 KPA43676.1 - 6.6e-89 296.9 60.6 1.2e-46 158.8 23.6 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KPA43676.1 - 7.8e-36 121.9 13.9 5.5e-33 112.7 0.0 3.9 4 0 0 4 4 4 2 CDR ABC transporter ABC_tran PF00005.27 KPA43676.1 - 6.5e-34 117.4 0.0 1.7e-16 60.9 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KPA43676.1 - 3.8e-18 65.9 0.0 8.9e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KPA43676.1 - 8.3e-08 32.8 0.1 0.00049 20.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KPA43676.1 - 1.9e-05 24.7 0.1 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KPA43676.1 - 7.2e-05 22.4 0.0 0.00094 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KPA43676.1 - 0.00019 21.3 0.4 0.35 10.6 0.0 2.7 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KPA43676.1 - 0.00033 20.9 0.1 0.18 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPA43676.1 - 0.00033 21.2 0.1 0.038 14.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KPA43676.1 - 0.0024 17.6 0.4 0.036 13.8 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KPA43676.1 - 0.0053 16.9 0.0 0.56 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KPA43676.1 - 0.0088 16.5 0.3 8.5 6.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPA43676.1 - 0.029 14.1 0.2 5.8 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KPA43676.1 - 0.042 14.3 0.1 6.1 7.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KPA43676.1 - 0.055 13.1 1.2 0.16 11.5 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 KPA43676.1 - 0.06 12.8 0.0 3.6 7.0 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPA43676.1 - 0.091 13.3 0.1 0.23 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KPA43676.1 - 0.15 12.3 0.3 3 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Bac_surface_Ag PF01103.23 KPA43677.1 - 4.2e-37 128.3 0.1 5.6e-37 127.9 0.1 1.2 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.26 KPA43678.1 - 7.5e-21 74.3 0.0 1.1e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SK_channel PF03530.14 KPA43680.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Calcium-activated SK potassium channel FA_desaturase PF00487.24 KPA43680.1 - 7.9 6.2 17.4 7.4 6.3 0.3 2.7 2 1 0 2 2 2 0 Fatty acid desaturase AMP-binding PF00501.28 KPA43683.1 - 1.4e-73 247.9 0.0 2.2e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA43683.1 - 5.3e-06 27.3 0.1 1.3e-05 26.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Condensation PF00668.20 KPA43683.1 - 0.0047 15.7 0.1 1.3 7.6 0.0 2.1 2 0 0 2 2 2 2 Condensation domain p450 PF00067.22 KPA43684.1 - 2.1e-64 218.0 0.0 2.7e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 KPA43685.1 - 3.2e-30 105.2 1.0 4.1e-30 104.9 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43685.1 - 9.7e-09 35.2 7.1 1.6e-08 34.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clavanin PF05452.11 KPA43686.1 - 0.073 13.3 0.1 0.24 11.6 0.0 1.9 1 1 1 2 2 2 0 Clavanin Lge1 PF11488.8 KPA43686.1 - 2.3 8.5 6.8 1.9 8.7 0.2 2.5 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 RTA1 PF04479.13 KPA43689.1 - 2.2e-67 226.7 10.6 2.8e-67 226.4 10.6 1.1 1 0 0 1 1 1 1 RTA1 like protein ABC_trans_CmpB PF06541.11 KPA43689.1 - 0.068 13.4 11.5 0.021 15.0 4.4 2.3 2 0 0 2 2 2 0 Putative ABC-transporter type IV MpPF26 PF07666.11 KPA43689.1 - 2.7 8.1 12.1 0.062 13.4 1.1 2.7 3 0 0 3 3 3 0 M penetrans paralogue family 26 Pribosyltran PF00156.27 KPA43690.1 - 4.1e-07 29.7 0.0 5.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF3669 PF12417.8 KPA43691.1 - 0.00033 20.8 0.1 0.00067 19.8 0.1 1.5 1 0 0 1 1 1 1 Zinc finger protein Oxidored-like PF09791.9 KPA43692.1 - 6.1e-25 86.6 2.7 1.1e-24 85.8 2.7 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Wtap PF17098.5 KPA43692.1 - 0.015 15.3 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family DUF5522 PF17653.1 KPA43692.1 - 2.6 8.1 6.5 0.42 10.6 2.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5522) Vint PF14623.6 KPA43693.1 - 2.7e-64 216.0 0.1 4e-64 215.4 0.1 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 KPA43693.1 - 1.9e-28 98.4 0.0 3.2e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 KPA43693.1 - 6.4e-16 59.1 0.0 1.2e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KPA43693.1 - 1.6e-15 57.4 0.0 1.8e-14 54.0 0.0 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KPA43693.1 - 2.9e-14 53.6 0.0 5.7e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Hint PF01079.20 KPA43693.1 - 0.0054 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Hint module UPF0253 PF06786.12 KPA43693.1 - 0.17 12.2 0.0 3.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) DUF1489 PF07370.11 KPA43694.1 - 0.17 11.6 0.1 0.31 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) LcrG PF07216.12 KPA43695.1 - 0.03 14.2 1.7 0.077 12.9 1.7 1.7 1 0 0 1 1 1 0 LcrG protein Ndc1_Nup PF09531.10 KPA43695.1 - 2.3 6.8 9.2 2.8 6.5 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GCR1_C PF12550.8 KPA43696.1 - 2.2e-19 69.6 2.2 2.9e-19 69.2 0.9 1.9 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes KIAA1430 PF13879.6 KPA43696.1 - 0.048 14.4 0.1 0.12 13.1 0.1 1.7 1 0 0 1 1 1 0 KIAA1430 homologue BLOC1_2 PF10046.9 KPA43696.1 - 0.49 10.7 4.1 0.24 11.7 1.4 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Trypan_PARP PF05887.11 KPA43696.1 - 0.61 10.1 12.1 1.7 8.6 12.1 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) eIF3_subunit PF08597.10 KPA43697.1 - 0.019 14.9 3.9 0.023 14.6 3.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit YABBY PF04690.13 KPA43697.1 - 0.23 12.0 2.7 0.31 11.6 2.7 1.2 1 0 0 1 1 1 0 YABBY protein AcetylCoA_hydro PF02550.15 KPA43698.1 - 7.8e-47 159.8 0.0 1.7e-46 158.7 0.0 1.6 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KPA43698.1 - 2.9e-42 144.2 0.0 4.5e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain PUF PF00806.19 KPA43699.1 - 1.2e-38 128.6 4.5 1.4e-05 24.5 0.0 8.3 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat AbiTii PF18864.1 KPA43699.1 - 0.0025 18.0 0.0 0.0079 16.4 0.0 1.8 1 0 0 1 1 1 1 AbiTii CPL PF08144.11 KPA43699.1 - 0.048 14.0 1.1 7.4 6.9 0.0 3.5 3 2 1 4 4 4 0 CPL (NUC119) domain DUF1640 PF07798.11 KPA43700.1 - 7.4e-48 162.9 7.9 7.4e-48 162.9 7.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Nnf1 PF03980.14 KPA43701.1 - 1.2e-34 119.0 0.8 1.2e-34 119.0 0.8 2.8 2 1 1 3 3 3 1 Nnf1 Dynamin_M PF01031.20 KPA43701.1 - 0.078 12.2 0.1 4.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Dynamin central region ADIP PF11559.8 KPA43701.1 - 0.1 12.7 0.8 0.1 12.7 0.8 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Snapin_Pallidin PF14712.6 KPA43701.1 - 0.13 12.7 3.3 0.11 12.9 1.0 2.2 2 0 0 2 2 2 0 Snapin/Pallidin DUF948 PF06103.11 KPA43701.1 - 0.15 12.4 2.3 0.25 11.6 0.8 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Trypan_PARP PF05887.11 KPA43701.1 - 1.4 8.9 7.9 2.8 7.9 7.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF16 PF01519.16 KPA43701.1 - 1.7 9.2 8.1 1.2 9.7 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 PH_9 PF15410.6 KPA43702.1 - 0.0011 19.3 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KPA43702.1 - 0.009 16.5 0.1 0.017 15.6 0.1 1.5 1 0 0 1 1 1 1 PH domain NTF2 PF02136.20 KPA43703.1 - 1.4e-24 86.9 0.4 2.2e-24 86.3 0.4 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KPA43703.1 - 6.6e-07 29.1 0.1 1.4e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KPA43703.1 - 0.039 14.0 0.5 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Ribosomal_L10 PF00466.20 KPA43704.1 - 1.3e-21 76.6 0.0 2e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KPA43704.1 - 2.9e-21 75.2 0.0 4.7e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Glyco_transf_25 PF01755.17 KPA43704.1 - 0.071 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) U1snRNP70_N PF12220.8 KPA43705.1 - 3.5e-26 91.7 6.4 7.4e-26 90.6 6.4 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KPA43705.1 - 1.7e-10 40.6 0.2 6.8e-10 38.6 0.2 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPA43705.1 - 0.001 19.1 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif L51_S25_CI-B8 PF05047.16 KPA43706.1 - 1e-12 47.8 0.0 5.5e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.18 KPA43707.1 - 1.6e-87 292.9 0.2 1.9e-87 292.7 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MIP-T3_C PF17749.1 KPA43707.1 - 0.017 15.1 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region CutC PF03932.14 KPA43707.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 CutC family zf-C2H2_4 PF13894.6 KPA43708.1 - 0.028 15.2 4.3 7.4 7.7 0.7 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA43708.1 - 0.088 13.3 5.7 0.92 10.1 0.0 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type Zn_clus PF00172.18 KPA43709.1 - 2.1e-09 37.3 6.3 3.3e-09 36.7 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KPA43712.1 - 0.00021 21.4 12.4 0.00037 20.5 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF543 PF04418.12 KPA43713.1 - 2.8e-29 100.9 0.0 3.2e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.9 KPA43714.1 - 3.8e-65 219.7 5.5 1.5e-64 217.7 1.6 3.4 3 0 0 3 3 3 1 Urb2/Npa2 family Telomere_reg-2 PF10193.9 KPA43714.1 - 0.038 14.4 0.9 0.31 11.5 0.1 2.9 2 1 1 3 3 3 0 Telomere length regulation protein partial_CstF PF15861.5 KPA43714.1 - 0.12 12.2 0.1 0.58 10.0 0.1 2.2 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain adh_short PF00106.25 KPA43715.1 - 2e-29 102.5 0.0 3e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA43715.1 - 7e-20 71.6 0.0 1.2e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA43715.1 - 6.4e-12 45.7 0.0 1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KPA43715.1 - 0.0033 17.4 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 KPA43715.1 - 0.0066 16.2 0.2 0.015 15.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GDP_Man_Dehyd PF16363.5 KPA43715.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KPA43715.1 - 0.02 14.8 0.0 0.27 11.1 0.0 2.2 1 1 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 KPA43715.1 - 0.024 13.9 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Big_3_5 PF16640.5 KPA43715.1 - 0.051 13.8 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) 3HCDH_N PF02737.18 KPA43715.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KPA43715.1 - 0.13 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KPA43715.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NRDE-2 PF08424.10 KPA43716.1 - 1.9e-101 339.4 8.9 4.9e-99 331.5 4.8 3.3 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference PI-PLC-X PF00388.19 KPA43716.1 - 8e-61 203.9 0.0 1.4e-60 203.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KPA43716.1 - 4.5e-40 136.6 0.0 4.5e-40 136.6 0.0 2.8 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain Nuf2 PF03800.14 KPA43716.1 - 0.11 12.7 0.2 14 5.8 0.1 2.9 3 0 0 3 3 3 0 Nuf2 family TPR_14 PF13428.6 KPA43716.1 - 0.31 12.0 4.5 41 5.4 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KPA43716.1 - 0.31 11.6 3.4 1.5 9.4 0.9 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPA43716.1 - 3.4 8.4 6.0 16 6.2 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Tmemb_170 PF10190.9 KPA43719.1 - 5.4e-28 97.5 13.6 6.4e-28 97.2 13.6 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF1275 PF06912.11 KPA43719.1 - 0.3 11.0 9.5 0.25 11.3 6.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) ICMT PF04140.14 KPA43720.1 - 1.8e-27 95.6 0.6 1.8e-27 95.6 0.6 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KPA43720.1 - 5.3e-11 42.9 1.3 5.3e-11 42.9 1.3 2.9 2 1 0 3 3 3 1 Phospholipid methyltransferase NnrU PF07298.11 KPA43720.1 - 0.00077 19.0 4.2 0.00089 18.8 3.2 1.7 1 1 0 1 1 1 1 NnrU protein DUF1295 PF06966.12 KPA43720.1 - 0.007 15.9 0.3 0.014 14.9 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) MBOAT PF03062.19 KPA43721.1 - 6.1e-19 68.6 16.5 9e-19 68.0 16.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KPA43721.1 - 0.00099 19.3 2.4 0.0032 17.7 2.4 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.32 KPA43722.1 - 1.9e-30 104.4 24.5 3.2e-05 24.6 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA43722.1 - 9.4e-14 51.5 0.1 0.052 13.8 0.0 5.8 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPA43722.1 - 0.0034 17.3 0.0 0.45 10.4 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KPA43722.1 - 0.13 10.5 0.0 0.26 9.5 0.0 1.3 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KPA43722.1 - 0.17 10.8 0.3 17 4.2 0.1 3.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KPA43722.1 - 0.2 10.4 0.0 0.39 9.4 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like Endonuclease_NS PF01223.23 KPA43723.1 - 1e-67 228.3 0.0 1.2e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Zip PF02535.22 KPA43724.1 - 5.4e-32 111.3 4.1 3.3e-31 108.7 4.1 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter zf-C2H2 PF00096.26 KPA43725.1 - 2.5e-26 90.6 54.1 1.4e-05 25.3 0.3 10.5 10 1 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA43725.1 - 1.9e-21 74.9 55.3 0.0015 19.2 1.4 10.8 11 0 0 11 11 11 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPA43725.1 - 2.1e-14 53.2 52.4 0.00051 20.3 0.4 10.7 12 0 0 12 12 10 5 Zinc-finger double domain FOXP-CC PF16159.5 KPA43725.1 - 1.2e-05 25.8 25.3 0.0067 17.0 0.1 6.6 5 1 1 7 7 6 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KPA43725.1 - 7.3e-05 23.0 16.6 0.0042 17.4 2.8 4.8 3 1 2 5 5 5 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KPA43725.1 - 8.3e-05 22.8 15.9 0.02 15.0 1.0 4.5 3 2 0 4 4 4 2 Aberrant zinc-finger zf-met PF12874.7 KPA43725.1 - 0.0024 18.2 14.2 0.41 11.1 0.1 5.7 7 0 0 7 7 5 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KPA43725.1 - 0.0049 16.6 0.1 0.0049 16.6 0.1 8.6 10 0 0 10 10 10 2 C2H2-type zinc-finger domain zf-TRAF PF02176.18 KPA43725.1 - 0.009 16.7 0.9 0.009 16.7 0.9 6.2 4 2 4 8 8 8 2 TRAF-type zinc finger DUF4187 PF13821.6 KPA43725.1 - 0.032 14.0 0.4 0.2 11.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) zinc_ribbon_9 PF14369.6 KPA43725.1 - 0.095 13.0 0.1 0.095 13.0 0.1 4.1 5 0 0 5 5 5 0 zinc-ribbon zf_C2H2_ZHX PF18387.1 KPA43725.1 - 0.11 12.1 9.3 0.15 11.7 0.0 4.2 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-RING_7 PF02591.15 KPA43725.1 - 0.14 12.4 2.0 1.2 9.3 0.1 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf_Hakai PF18408.1 KPA43725.1 - 0.21 11.3 13.0 0.34 10.7 0.1 5.2 5 0 0 5 5 5 0 C2H2 Hakai zinc finger domain zf-C2H2_jaz PF12171.8 KPA43725.1 - 0.26 11.6 30.3 1.6 9.1 0.0 7.4 10 0 0 10 10 8 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KPA43725.1 - 0.3 11.8 23.4 0.23 12.1 0.6 5.2 4 2 2 6 6 5 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 KPA43725.1 - 0.54 10.6 41.7 1.4 9.3 5.3 7.3 4 3 3 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding Ogr_Delta PF04606.12 KPA43725.1 - 0.65 10.0 5.1 23 5.0 0.0 3.8 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zinc_ribbon_4 PF13717.6 KPA43725.1 - 1.3 9.0 8.1 5.6 7.0 0.3 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KPA43725.1 - 2.3 8.4 15.3 3.2 8.0 2.0 4.5 3 1 3 6 6 6 0 Zinc ribbon domain RNA_pol_Rpb6 PF01192.22 KPA43726.1 - 5.2e-17 61.5 0.1 9.8e-17 60.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.12 KPA43726.1 - 2.8 7.9 6.0 28 4.6 6.0 1.9 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Esterase PF00756.20 KPA43728.1 - 1.7e-47 162.2 0.0 1.9e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KPA43728.1 - 1.9e-05 24.2 0.0 0.0003 20.3 0.0 2.1 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KPA43728.1 - 0.00064 19.3 0.0 0.00086 18.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KPA43728.1 - 0.00073 18.9 0.0 0.0045 16.3 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KPA43728.1 - 0.0019 17.8 0.0 0.0043 16.6 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KPA43728.1 - 0.0047 15.9 0.0 0.0082 15.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KPA43728.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KPA43728.1 - 0.046 13.6 0.0 8.4 6.2 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 KPA43728.1 - 0.048 12.3 0.0 0.073 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PGAP1 PF07819.13 KPA43728.1 - 0.2 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Afi1 PF07792.12 KPA43729.1 - 5.9e-47 159.5 0.6 1.1e-46 158.6 0.6 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KPA43729.1 - 1.2e-36 125.1 0.0 2.2e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KPA43729.1 - 4.9e-07 28.8 0.0 0.007 15.1 0.0 3.7 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.9 KPA43729.1 - 0.052 13.1 0.0 0.69 9.4 0.0 2.8 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2347) QWRF PF04484.12 KPA43729.1 - 3.4 7.3 9.2 5.9 6.5 9.2 1.3 1 0 0 1 1 1 0 QWRF family DUF4746 PF15928.5 KPA43729.1 - 4.1 6.7 8.9 2.5 7.4 6.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Rib_recp_KP_reg PF05104.12 KPA43729.1 - 8.2 7.4 16.5 0.086 13.9 4.3 2.5 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region EF-hand_6 PF13405.6 KPA43730.1 - 2.4e-12 45.7 0.2 8.3e-05 22.2 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KPA43730.1 - 9.5e-10 37.3 1.0 0.00026 20.3 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KPA43730.1 - 3.7e-07 30.5 0.0 0.024 15.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KPA43730.1 - 1.9e-05 23.9 1.6 0.16 11.5 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KPA43730.1 - 2.5e-05 24.0 0.2 0.02 14.7 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KPA43730.1 - 5.9e-05 23.3 0.0 0.54 10.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain TPR_1 PF00515.28 KPA43731.1 - 4.2e-37 124.5 18.8 7.9e-08 31.8 0.3 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KPA43731.1 - 5.5e-35 116.7 17.1 1.7e-05 24.6 0.1 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.31 KPA43731.1 - 7.9e-28 96.4 5.7 1.3e-27 95.6 3.5 2.5 3 0 0 3 3 2 1 DnaJ domain TPR_11 PF13414.6 KPA43731.1 - 1.1e-24 85.8 12.9 2.3e-05 24.0 0.4 6.4 5 1 1 6 6 6 5 TPR repeat TPR_19 PF14559.6 KPA43731.1 - 4.2e-24 84.8 13.5 2.7e-09 37.4 0.1 5.5 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KPA43731.1 - 8.4e-21 72.4 9.5 0.00017 21.5 0.2 7.1 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KPA43731.1 - 2e-20 73.1 3.3 7.8e-06 26.4 0.5 6.1 4 3 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KPA43731.1 - 3e-16 59.5 8.1 2.9e-06 27.5 0.4 6.1 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KPA43731.1 - 6.6e-16 57.6 11.2 0.006 17.3 0.0 8.1 5 2 4 9 9 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KPA43731.1 - 2e-15 56.0 13.4 0.012 15.9 0.3 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 KPA43731.1 - 2.3e-11 43.7 3.9 0.018 15.1 0.2 4.6 2 2 3 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA43731.1 - 6.3e-11 42.4 8.6 9.2e-05 22.6 0.7 4.4 4 1 1 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KPA43731.1 - 1e-09 37.7 5.0 0.64 10.2 0.0 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KPA43731.1 - 7.4e-09 35.2 5.6 0.064 12.5 0.0 4.0 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 KPA43731.1 - 8e-09 35.6 13.5 0.4 11.4 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat BTAD PF03704.17 KPA43731.1 - 8.6e-05 23.0 4.6 0.3 11.5 0.1 4.2 2 2 2 4 4 4 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 KPA43731.1 - 0.00014 21.6 10.7 6.3 6.8 0.0 6.2 5 1 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 KPA43731.1 - 0.00015 21.3 3.0 0.33 10.3 1.7 2.8 2 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_4 PF07721.14 KPA43731.1 - 0.0002 21.6 1.3 0.76 10.6 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat ChAPs PF09295.10 KPA43731.1 - 0.00024 20.3 0.0 0.13 11.2 0.0 2.5 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 KPA43731.1 - 0.00031 20.7 3.9 12 6.0 0.0 5.0 3 1 2 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 KPA43731.1 - 0.00066 19.7 1.0 0.07 13.1 0.3 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF627) DUF3856 PF12968.7 KPA43731.1 - 0.0016 18.5 3.9 42 4.2 0.0 5.4 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) Alkyl_sulf_dimr PF14863.6 KPA43731.1 - 0.0054 17.2 0.4 2.6 8.5 0.0 3.4 2 1 0 2 2 2 1 Alkyl sulfatase dimerisation TPR_20 PF14561.6 KPA43731.1 - 0.013 15.8 4.8 11 6.4 0.0 4.7 2 2 2 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KPA43731.1 - 0.017 14.5 0.0 5.5 6.3 0.1 2.5 2 0 0 2 2 2 0 Coatomer epsilon subunit SRP_TPR_like PF17004.5 KPA43731.1 - 0.026 14.6 1.4 1.8 8.6 0.1 3.6 4 1 0 4 4 4 0 Putative TPR-like repeat Tap-RNA_bind PF09162.10 KPA43731.1 - 0.15 11.9 0.0 0.96 9.3 0.0 2.3 2 0 0 2 2 2 0 Tap, RNA-binding TPM_phosphatase PF04536.14 KPA43731.1 - 0.17 12.1 1.1 4.4 7.5 0.0 3.2 3 0 0 3 3 3 0 TPM domain MIT PF04212.18 KPA43731.1 - 0.7 10.0 13.8 0.66 10.1 0.2 4.9 5 1 0 5 5 4 0 MIT (microtubule interacting and transport) domain Med10 PF09748.9 KPA43732.1 - 1.3e-53 180.0 0.1 1.6e-53 179.8 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF1825 PF08855.10 KPA43732.1 - 0.02 14.8 0.1 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) Talin_middle PF09141.10 KPA43732.1 - 0.08 13.0 0.0 1.6 8.8 0.0 2.0 2 0 0 2 2 2 0 Talin, middle domain DUF3877 PF12993.7 KPA43732.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) MYCBPAP PF14646.6 KPA43733.1 - 0.42 9.5 10.6 2.1 7.2 0.2 3.5 1 1 3 4 4 4 0 MYCBP-associated protein family PSD2 PF07624.11 KPA43733.1 - 0.43 10.4 3.4 16 5.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1585) Iso_dh PF00180.20 KPA43734.1 - 6.5e-132 439.9 0.0 7.5e-132 439.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.29 KPA43735.1 - 3.8e-10 39.5 4.8 5.9e-10 38.9 4.8 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KPA43735.1 - 0.021 14.4 2.8 0.036 13.6 2.8 1.3 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 KPA43735.1 - 1.9 8.9 3.5 0.85 10.0 0.9 1.7 2 0 0 2 2 2 0 C1 domain DUF4451 PF14616.6 KPA43736.1 - 3e-24 85.6 0.2 5.2e-24 84.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) PRCC PF10253.9 KPA43737.1 - 2.3 8.9 6.1 4.6 8.0 5.9 1.6 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2236 PF09995.9 KPA43738.1 - 7.9e-10 39.3 0.1 1.1e-09 38.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) FlhD PF05247.13 KPA43738.1 - 0.095 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhD) TfoX_C PF04994.13 KPA43738.1 - 0.12 12.5 0.1 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 TfoX C-terminal domain Actin PF00022.19 KPA43739.1 - 4.5e-28 98.0 0.0 3.8e-18 65.3 0.0 3.0 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KPA43739.1 - 0.0078 15.4 0.3 0.74 8.9 0.0 2.3 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 KPA43739.1 - 0.014 15.8 0.0 0.15 12.5 0.0 2.5 3 0 0 3 3 3 0 Cell division protein FtsA MreB_Mbl PF06723.13 KPA43739.1 - 0.13 11.1 0.0 1.6 7.4 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein MFS_1 PF07690.16 KPA43740.1 - 5.1e-22 78.3 27.1 1.3e-12 47.4 4.6 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 KPA43740.1 - 1.1e-05 24.2 0.1 1.1e-05 24.2 0.1 2.5 2 2 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 KPA43740.1 - 8e-05 21.7 0.0 0.17 10.7 0.1 3.1 2 2 0 3 3 3 2 MFS_1 like family Sugar_tr PF00083.24 KPA43740.1 - 0.044 12.7 11.6 0.93 8.3 0.3 3.4 3 0 0 3 3 3 0 Sugar (and other) transporter Stm1_N PF09598.10 KPA43742.1 - 5e-12 46.5 1.5 5e-12 46.5 1.5 4.2 3 1 1 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.15 KPA43742.1 - 0.0003 21.6 14.0 0.0003 21.6 14.0 2.9 3 2 1 4 4 4 1 Hyaluronan / mRNA binding family V-SNARE_C PF12352.8 KPA43743.1 - 0.031 14.5 0.9 0.057 13.7 0.3 1.8 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus bZIP_1 PF00170.21 KPA43744.1 - 5.2e-06 26.5 6.3 5.2e-06 26.5 6.3 1.9 2 0 0 2 2 2 1 bZIP transcription factor Myb_DNA-bind_3 PF12776.7 KPA43744.1 - 0.11 13.5 1.9 5.7 8.0 0.0 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF5595 PF18077.1 KPA43744.1 - 0.26 11.4 1.8 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DUF2852 PF11014.8 KPA43744.1 - 2.1 8.5 5.2 1.8 8.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DUF4407 PF14362.6 KPA43744.1 - 2.4 7.4 9.6 2.5 7.4 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Glyco_hydro_16 PF00722.21 KPA43745.1 - 1.1e-11 44.5 0.7 1.6e-11 44.0 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WW PF00397.26 KPA43746.1 - 6.1e-10 39.0 2.7 1.6e-09 37.7 2.7 1.7 1 0 0 1 1 1 1 WW domain WRW PF10206.9 KPA43746.1 - 0.034 14.5 0.4 0.071 13.5 0.4 1.5 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f RIX1 PF08167.12 KPA43747.1 - 5e-48 163.3 0.2 1e-47 162.3 0.2 1.5 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Ribosomal_60s PF00428.19 KPA43747.1 - 2.7 8.7 13.1 9.1 6.9 4.6 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_8 PF13181.6 KPA43748.1 - 7.4e-11 41.4 2.7 0.012 15.8 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPA43748.1 - 7.9e-11 41.2 13.6 0.0099 15.9 0.0 7.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KPA43748.1 - 1.1e-09 38.3 22.0 0.043 14.6 0.0 8.7 11 0 0 11 11 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KPA43748.1 - 1.2e-09 37.5 1.1 0.2 11.5 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KPA43748.1 - 2.7e-08 33.6 3.4 0.02 15.2 0.0 6.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KPA43748.1 - 4.6e-06 26.7 0.2 0.44 10.7 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPA43748.1 - 3.9e-05 24.1 3.4 0.12 12.9 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPA43748.1 - 0.00022 21.0 6.0 3.2 8.0 0.2 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPA43748.1 - 0.0036 17.9 9.3 1.5 9.5 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPA43748.1 - 0.0071 16.6 11.2 5.1 7.5 0.5 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KPA43748.1 - 0.02 15.5 3.0 1.1e+02 3.9 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPA43748.1 - 2.4 9.0 0.0 2.4 9.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Xpo1 PF08389.12 KPA43749.1 - 8.1e-36 123.3 3.3 1.6e-35 122.4 0.2 3.1 4 0 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 KPA43749.1 - 0.00025 21.0 0.1 3.9 8.0 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat Aa_trans PF01490.18 KPA43751.1 - 6.2e-45 153.6 32.9 7.4e-45 153.4 32.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MMPL PF03176.15 KPA43751.1 - 0.018 14.0 5.9 0.035 13.1 5.0 1.9 2 0 0 2 2 2 0 MMPL family LRR19-TM PF15176.6 KPA43751.1 - 0.26 11.3 0.1 0.26 11.3 0.1 2.5 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain RTA1 PF04479.13 KPA43752.1 - 8.3e-67 224.8 16.3 8.3e-67 224.8 16.3 1.4 2 0 0 2 2 2 1 RTA1 like protein Ca_hom_mod PF14798.6 KPA43752.1 - 0.03 13.4 0.1 0.063 12.4 0.1 1.5 1 0 0 1 1 1 0 Calcium homeostasis modulator Peptidase_M18 PF02127.15 KPA43753.1 - 3.3e-171 569.8 0.0 5.3e-171 569.2 0.0 1.3 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Whi5 PF08528.11 KPA43754.1 - 1.5e-11 43.7 0.1 2.2e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Whi5 like Glyco_transf_90 PF05686.12 KPA43756.1 - 1.8e-14 53.5 0.1 3.6e-11 42.6 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 Oxidored_q6 PF01058.22 KPA43757.1 - 2.6e-22 79.1 0.1 3.7e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit zf-CCHC PF00098.23 KPA43758.1 - 0.00044 20.2 3.2 0.00075 19.5 3.2 1.4 1 0 0 1 1 1 1 Zinc knuckle MCR PF18509.1 KPA43758.1 - 0.0086 15.6 0.5 0.014 14.9 0.5 1.4 1 0 0 1 1 1 1 Magnetochrome domain zf-CCHC_3 PF13917.6 KPA43758.1 - 0.02 14.9 1.7 0.054 13.5 1.7 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KPA43758.1 - 0.093 12.5 1.3 0.19 11.5 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle WDCP PF15390.6 KPA43758.1 - 0.13 10.6 5.4 0.16 10.3 5.4 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family CorA PF01544.18 KPA43758.1 - 0.22 10.8 0.2 0.29 10.4 0.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PAD_M PF08527.10 KPA43758.1 - 0.28 10.8 2.4 0.49 10.1 0.2 1.9 1 1 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain Ferlin_C PF16165.5 KPA43758.1 - 0.79 9.7 10.6 1.3 9.0 2.7 2.2 2 0 0 2 2 2 0 Ferlin C-terminus TMPIT PF07851.13 KPA43758.1 - 1 8.5 10.7 0.041 13.1 4.8 1.7 1 1 1 2 2 2 0 TMPIT-like protein DUF4207 PF13904.6 KPA43758.1 - 3.1 7.4 17.2 4.3 6.9 17.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) RRP7 PF12923.7 KPA43760.1 - 8.9e-30 103.3 14.9 1.7e-29 102.4 14.9 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KPA43760.1 - 1e-16 61.2 0.1 2.5e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain ADIP PF11559.8 KPA43761.1 - 6.3e-39 133.5 7.2 6.3e-39 133.5 7.2 2.3 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KPA43761.1 - 0.0006 19.4 2.8 0.0006 19.4 2.8 2.1 2 0 0 2 2 2 1 Golgin subfamily A member 5 DUF641 PF04859.12 KPA43761.1 - 0.03 14.7 9.9 0.089 13.1 1.9 3.3 3 2 1 4 4 4 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KPA43761.1 - 0.17 10.7 7.1 0.057 12.3 1.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 KPA43761.1 - 1.2 9.3 11.4 1.4 9.0 4.5 2.8 2 1 0 2 2 2 0 Tropomyosin like DUF724 PF05266.14 KPA43761.1 - 2.7 7.8 7.0 0.51 10.1 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) BRE1 PF08647.11 KPA43761.1 - 3.4 7.8 9.3 0.91 9.6 4.6 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Macoilin PF09726.9 KPA43761.1 - 4.4 5.8 15.9 2.2 6.7 5.3 2.2 2 0 0 2 2 2 0 Macoilin family TMPIT PF07851.13 KPA43761.1 - 6.9 5.8 5.6 10 5.3 1.4 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF948 PF06103.11 KPA43761.1 - 8.5 6.7 6.8 7.4 6.9 0.3 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) FHA PF00498.26 KPA43762.1 - 3.1e-15 56.3 0.0 7e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KPA43762.1 - 0.0025 18.1 0.0 0.009 16.3 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF1769 PF08588.10 KPA43762.1 - 0.04 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) IFRD PF05004.13 KPA43763.1 - 2.2e-48 164.9 2.0 2.8e-48 164.6 2.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DUF3776 PF12618.8 KPA43763.1 - 0.023 15.2 0.2 0.063 13.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) Clathrin PF00637.20 KPA43763.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Region in Clathrin and VPS Claudin_2 PF13903.6 KPA43764.1 - 0.0043 16.8 8.7 0.27 10.9 8.7 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Spo7 PF03907.13 KPA43764.1 - 0.25 10.8 0.4 0.42 10.0 0.4 1.3 1 0 0 1 1 1 0 Spo7-like protein TauD PF02668.16 KPA43764.1 - 0.25 11.1 0.0 8.3 6.1 0.0 2.0 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family PhyH PF05721.13 KPA43765.1 - 4.8e-62 209.9 0.0 5.7e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KPA43765.1 - 0.0069 16.8 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF2373 PF10180.9 KPA43766.1 - 1.9e-25 88.4 0.4 3.5e-24 84.4 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) zf-CCHC_6 PF15288.6 KPA43766.1 - 0.15 11.9 0.4 0.41 10.5 0.2 1.8 2 0 0 2 2 2 0 Zinc knuckle Proteasome PF00227.26 KPA43767.1 - 9.9e-48 162.1 0.0 1.4e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KPA43767.1 - 2.5e-11 43.0 0.2 5.4e-11 42.0 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TMEM234 PF10639.9 KPA43769.1 - 3.5e-33 114.1 0.4 5.9e-33 113.3 0.4 1.4 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KPA43769.1 - 0.00025 21.2 5.8 0.18 12.0 3.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family PetM PF08041.11 KPA43769.1 - 0.068 12.8 1.6 0.068 12.8 1.6 2.9 3 0 0 3 3 3 0 PetM family of cytochrome b6f complex subunit 7 Con-6 PF10346.9 KPA43770.1 - 2.9e-30 104.0 5.5 4.1e-17 61.9 1.2 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.7 KPA43770.1 - 0.02 14.7 2.4 0.069 13.0 0.5 2.0 1 1 0 2 2 2 0 SpoIIIAH-like protein Osteoregulin PF07175.11 KPA43770.1 - 0.054 13.7 2.5 0.056 13.6 1.6 1.4 1 1 0 1 1 1 0 Osteoregulin WD40 PF00400.32 KPA43771.1 - 1.5e-39 133.2 17.6 5.5e-10 39.7 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA43771.1 - 6.6e-14 52.0 0.8 0.023 15.0 0.0 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA43771.1 - 6.3e-08 32.0 0.4 0.23 10.4 0.0 4.6 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KPA43771.1 - 1.3e-06 27.4 3.9 0.081 11.6 0.1 4.8 3 1 1 4 4 4 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KPA43771.1 - 2.3e-05 23.5 4.4 2.7e-05 23.3 0.1 2.9 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 KPA43771.1 - 0.0025 17.0 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region Frtz PF11768.8 KPA43771.1 - 0.0068 14.8 0.0 0.066 11.5 0.0 2.2 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 KPA43771.1 - 0.0069 16.1 1.1 6.8 6.3 0.1 3.3 1 1 2 3 3 3 1 TUP1-like enhancer of split CN_hydrolase PF00795.22 KPA43772.1 - 7.1e-58 196.0 0.0 8.3e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_2 PF07646.15 KPA43772.1 - 0.16 12.0 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 Kelch motif Spermine_synth PF01564.17 KPA43773.1 - 5.4e-74 247.7 0.0 7.4e-74 247.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KPA43773.1 - 2.3e-24 85.0 0.0 4e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KPA43773.1 - 0.0002 22.0 0.0 0.00037 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA43773.1 - 0.0066 17.2 0.2 0.024 15.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KPA43773.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.16 KPA43773.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Trimer_CC PF08954.11 KPA43774.1 - 0.036 13.6 0.0 0.19 11.3 0.0 2.2 1 0 0 1 1 1 0 Trimerisation motif Ribosomal_L16 PF00252.18 KPA43776.1 - 1.2e-45 154.7 0.0 1.6e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.26 KPA43777.1 - 1e-24 86.1 0.0 1.1e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3450 PF11932.8 KPA43778.1 - 0.013 14.8 18.4 0.45 9.8 15.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Cytomega_UL20A PF05984.12 KPA43778.1 - 0.35 11.2 3.0 1.1 9.5 0.4 2.6 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein HeLo PF14479.6 KPA43778.1 - 0.43 10.4 7.8 1.5 8.6 7.8 1.9 1 0 0 1 1 1 0 Prion-inhibition and propagation Bacillus_HBL PF05791.11 KPA43778.1 - 0.76 9.6 8.5 0.47 10.3 6.5 1.6 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ALMT PF11744.8 KPA43778.1 - 9.5 4.9 12.8 18 4.0 12.8 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Vac7 PF12751.7 KPA43779.1 - 9.8e-160 532.1 9.5 9.8e-160 532.1 9.5 2.3 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 PRP1_N PF06424.12 KPA43780.1 - 6.4e-51 172.6 9.6 1.4e-50 171.5 9.6 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KPA43780.1 - 2.7e-31 105.6 38.1 0.00024 21.7 0.1 14.4 6 3 9 15 15 14 10 Tetratricopeptide repeat TPR_19 PF14559.6 KPA43780.1 - 1.1e-26 93.2 14.7 1.1e-06 29.1 0.1 9.7 6 3 4 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 KPA43780.1 - 1.3e-12 48.1 19.7 7e-05 23.4 0.0 7.5 5 1 4 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.6 KPA43780.1 - 4.6e-12 45.4 5.5 3.8 8.1 0.0 10.0 11 1 1 12 12 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPA43780.1 - 9.1e-10 38.0 2.2 0.054 13.7 0.0 8.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPA43780.1 - 7.7e-09 35.0 16.3 1.1 9.5 0.0 9.7 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 KPA43780.1 - 2.4e-07 30.3 1.4 0.14 11.8 0.0 5.5 6 0 0 6 6 6 2 TPR repeat TPR_1 PF00515.28 KPA43780.1 - 7.8e-05 22.3 0.2 2.2 8.2 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.8 KPA43780.1 - 8.2e-05 21.7 5.9 0.57 9.0 0.0 5.4 3 1 2 5 5 5 2 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 KPA43780.1 - 9.6e-05 22.5 16.5 0.0046 17.1 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA43780.1 - 0.00011 22.4 0.1 2 8.7 0.0 4.5 4 1 1 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KPA43780.1 - 0.00031 20.0 21.7 0.016 14.5 5.0 6.0 3 1 2 5 5 5 1 Tetratricopeptide repeat DUF3808 PF10300.9 KPA43780.1 - 0.0012 17.7 0.6 16 4.1 0.0 5.0 3 2 1 5 5 5 0 Protein of unknown function (DUF3808) TPR_21 PF09976.9 KPA43780.1 - 0.0042 16.8 8.3 0.36 10.5 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KPA43780.1 - 0.0047 17.5 7.0 22 6.0 0.0 8.0 10 0 0 10 10 8 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KPA43780.1 - 0.016 15.1 4.4 5.4 6.9 0.0 4.7 4 2 2 6 6 6 0 Virulence factor membrane-bound polymerase, C-terminal Suf PF05843.14 KPA43780.1 - 0.024 14.6 1.2 10 6.0 0.0 4.0 4 1 0 4 4 4 0 Suppressor of forked protein (Suf) OsmC PF02566.19 KPA43780.1 - 0.12 12.9 0.1 19 5.8 0.0 3.2 2 1 0 2 2 2 0 OsmC-like protein GILT PF03227.16 KPA43780.1 - 0.19 12.0 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Apolipoprotein PF01442.18 KPA43781.1 - 0.1 12.5 1.9 0.13 12.1 1.9 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PPR_2 PF13041.6 KPA43782.1 - 7.9e-05 22.8 0.0 0.13 12.4 0.0 2.7 2 0 0 2 2 2 2 PPR repeat family Lin-8 PF03353.15 KPA43782.1 - 0.096 12.2 10.6 0.017 14.7 5.1 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Glyco_H_20C_C PF18088.1 KPA43782.1 - 1.2 9.0 4.6 0.58 10.0 2.2 1.7 2 0 0 2 2 2 0 Glycoside Hydrolase 20C C-terminal domain PP2C PF00481.21 KPA43783.1 - 5.6e-85 285.1 0.0 8.1e-85 284.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KPA43783.1 - 0.025 14.5 0.0 0.86 9.5 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) TPM_phosphatase PF04536.14 KPA43783.1 - 0.093 12.9 0.2 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 TPM domain He_PIG PF05345.12 KPA43784.1 - 1.1e-14 54.4 6.6 3.1e-06 27.3 0.0 4.4 4 0 0 4 4 4 3 Putative Ig domain TMEM154 PF15102.6 KPA43784.1 - 0.0001 22.2 0.2 0.0003 20.7 0.1 1.8 2 0 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.6 KPA43784.1 - 0.0045 16.8 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Hum_adeno_E3A PF05393.11 KPA43784.1 - 0.12 12.4 0.1 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Methyltransf_16 PF10294.9 KPA43785.1 - 2.7e-43 147.7 0.0 3.3e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KPA43785.1 - 0.0046 16.5 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KPA43785.1 - 0.0057 16.5 0.0 0.0075 16.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain DUF1712 PF08217.11 KPA43787.1 - 2.1e-12 46.4 0.5 2.1e-11 43.0 0.0 2.5 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1712) Presenilin PF01080.17 KPA43787.1 - 4.5 5.9 5.0 2.7 6.7 3.0 1.6 2 0 0 2 2 2 0 Presenilin CorA PF01544.18 KPA43788.1 - 0.00049 19.5 0.2 0.0009 18.6 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Kelch_4 PF13418.6 KPA43789.1 - 2e-24 85.3 16.2 3.8e-07 30.0 0.1 7.8 7 1 1 8 8 8 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KPA43789.1 - 8.6e-19 67.4 18.2 5.1e-05 23.4 0.1 7.7 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KPA43789.1 - 1.4e-18 66.4 4.5 2.8e-07 30.6 0.0 5.4 5 2 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KPA43789.1 - 8.9e-17 60.4 3.0 3.9e-08 32.7 0.0 5.3 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KPA43789.1 - 1.9e-14 53.2 0.1 1.8e-05 24.6 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KPA43789.1 - 1.8e-11 43.5 5.0 8.4e-06 25.6 0.2 5.2 5 1 0 5 5 5 4 Kelch motif HMG14_17 PF01101.18 KPA43789.1 - 0.29 12.1 13.9 0.9 10.5 13.9 1.8 1 0 0 1 1 1 0 HMG14 and HMG17 2Fe-2S_thioredx PF01257.19 KPA43790.1 - 4.3e-59 198.5 0.0 5.3e-59 198.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin AMP-binding PF00501.28 KPA43792.1 - 1.7e-85 287.2 0.0 2.2e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA43792.1 - 2.9e-10 41.0 0.1 7.3e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DAO PF01266.24 KPA43793.1 - 1.3e-47 163.1 1.9 1.5e-47 162.9 1.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPA43793.1 - 6.2e-06 25.7 0.3 0.00067 19.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA43793.1 - 5.6e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA43793.1 - 0.0012 18.1 0.0 0.043 13.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA43793.1 - 0.0013 17.5 0.5 0.63 8.7 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KPA43793.1 - 0.0043 16.2 0.2 0.0081 15.3 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KPA43793.1 - 0.0091 15.3 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KPA43793.1 - 0.016 15.2 0.7 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KPA43793.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 KPA43793.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.25 KPA43794.1 - 6.1e-44 150.4 0.0 2.3e-41 141.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA43794.1 - 4.1e-26 91.8 0.0 7.7e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase dCMP_cyt_deam_1 PF00383.23 KPA43795.1 - 1.1e-25 89.4 1.8 1.8e-25 88.7 1.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KPA43795.1 - 6.5e-09 35.7 0.2 1.3e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KPA43795.1 - 8.5e-06 26.3 0.0 2e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Plasmodium_Vir PF05795.11 KPA43795.1 - 0.0092 15.4 0.2 0.014 14.9 0.2 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein TFIIA_gamma_C PF02751.14 KPA43795.1 - 0.032 14.4 0.1 0.061 13.5 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit CoaE PF01121.20 KPA43795.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase ATG7_N PF16420.5 KPA43796.1 - 1.6e-111 372.7 0.0 2.2e-111 372.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KPA43796.1 - 3.1e-46 157.7 0.0 4.7e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KPA43796.1 - 0.035 14.2 0.0 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Chromo PF00385.24 KPA43797.1 - 0.4 10.6 3.4 4.4 7.3 0.3 2.8 1 1 1 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain PIG-F PF06699.11 KPA43799.1 - 2.6e-63 213.5 4.1 3.1e-63 213.2 4.1 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Rick_17kDa_Anti PF05433.15 KPA43799.1 - 0.043 13.7 4.4 3 7.8 0.2 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KPA43799.1 - 5.3 7.1 7.0 22 5.2 1.1 2.3 2 0 0 2 2 2 0 Glycine zipper SNF2_N PF00176.23 KPA43800.1 - 8.5e-50 169.4 0.1 1.5e-49 168.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KPA43800.1 - 3.2e-28 97.6 2.3 1.2e-27 95.8 2.3 2.1 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KPA43800.1 - 5.1e-19 68.7 1.8 2.3e-18 66.5 0.0 3.1 5 0 0 5 5 5 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA43800.1 - 3.2e-08 33.8 0.0 1.2e-07 31.9 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KPA43800.1 - 2.2e-07 30.4 1.6 3.7e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KPA43800.1 - 7.2e-06 25.9 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KPA43800.1 - 0.0011 18.7 0.0 0.0029 17.3 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF1216 PF06746.11 KPA43800.1 - 0.024 14.6 3.3 0.028 14.4 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) AAA_34 PF13872.6 KPA43800.1 - 0.05 12.5 0.5 3.5 6.4 0.1 2.4 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 Methyltransf_23 PF13489.6 KPA43801.1 - 1.3e-10 41.4 0.0 2.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA43801.1 - 1e-06 29.4 0.0 4e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA43801.1 - 6.1e-06 26.8 0.0 0.0001 22.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA43801.1 - 6.8e-06 26.7 0.0 0.00051 20.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA43801.1 - 0.0052 16.6 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA43801.1 - 0.098 12.0 0.0 0.52 9.6 0.0 2.0 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family S4 PF01479.25 KPA43802.1 - 8.2e-14 51.1 0.0 1.5e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KPA43802.1 - 6.1e-11 43.1 0.6 9.5e-11 42.5 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain THDPS_N_2 PF14805.6 KPA43802.1 - 0.04 14.2 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Ribosomal_S18 PF01084.20 KPA43803.1 - 1.1e-08 35.2 0.0 1.9e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 HTH_Tnp_Mu_1 PF02316.16 KPA43803.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Mu DNA-binding domain PPR_2 PF13041.6 KPA43804.1 - 0.00016 21.8 0.5 1.3 9.3 0.0 4.7 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.20 KPA43804.1 - 0.0013 18.8 2.8 0.92 9.9 0.1 4.9 4 0 0 4 4 4 1 PPR repeat Aldo_ket_red PF00248.21 KPA43805.1 - 3.9e-53 180.6 0.0 4.5e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.20 KPA43806.1 - 1.2e-12 48.2 24.9 2.3e-06 27.8 2.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 KPA43806.1 - 2.9e-05 23.2 16.3 0.0019 17.2 16.3 3.0 1 1 0 1 1 1 1 Ceramide synthase regulator SLC35F PF06027.12 KPA43806.1 - 0.013 15.0 4.2 0.022 14.3 3.7 1.7 1 1 0 1 1 1 0 Solute carrier family 35 Mannosyl_trans4 PF15971.5 KPA43806.1 - 0.048 13.5 2.7 0.15 11.9 2.7 1.8 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase Nuc_sug_transp PF04142.15 KPA43806.1 - 0.09 11.9 0.0 0.09 11.9 0.0 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter SieB PF14163.6 KPA43806.1 - 0.57 9.7 7.5 0.22 11.0 2.6 2.5 2 0 0 2 2 2 0 Super-infection exclusion protein B PufQ PF05398.11 KPA43806.1 - 1.2 9.3 4.5 0.34 11.1 0.3 2.4 2 0 0 2 2 2 0 PufQ cytochrome subunit F-box-like PF12937.7 KPA43807.1 - 8.2e-06 25.6 0.2 8.2e-06 25.6 0.2 2.5 2 0 0 2 2 2 1 F-box-like Cerato-platanin PF07249.12 KPA43809.1 - 4.4e-51 172.0 1.5 5.2e-51 171.7 1.5 1.0 1 0 0 1 1 1 1 Cerato-platanin GHMP_kinases_N PF00288.26 KPA43810.1 - 1.6e-10 41.1 0.0 3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KPA43810.1 - 2.8e-05 24.4 0.0 5.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal DHDPS PF00701.22 KPA43811.1 - 1.5e-29 102.6 0.2 2e-29 102.2 0.2 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family 4HBT_2 PF13279.6 KPA43812.1 - 1.3e-05 25.7 0.0 2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Phytochelatin_C PF09328.10 KPA43813.1 - 0.044 13.1 0.1 0.06 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) NPV_P10 PF05531.12 KPA43813.1 - 0.1 13.1 1.7 1.4 9.5 0.1 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KPA43813.1 - 0.16 12.0 0.7 0.36 10.9 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Acyl-CoA_dh_1 PF00441.24 KPA43814.1 - 4e-14 53.1 0.4 4.5e-13 49.7 0.2 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPA43814.1 - 5.1e-10 39.4 0.0 1.3e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AidB_N PF18158.1 KPA43814.1 - 1e-09 38.5 0.0 2.7e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Adaptive response protein AidB N-terminal domain A_deaminase PF00962.22 KPA43816.1 - 1.9e-26 93.2 0.0 7.1e-26 91.3 0.0 1.9 2 1 0 2 2 2 1 Adenosine/AMP deaminase NmrA PF05368.13 KPA43817.1 - 2.5e-12 46.9 0.0 2e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA43817.1 - 8.7e-11 42.1 0.0 9.9e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPA43817.1 - 0.0017 18.6 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Hydantoinase_B PF02538.14 KPA43818.1 - 2.3e-219 729.1 0.1 3.1e-219 728.7 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KPA43818.1 - 8.4e-105 350.2 0.9 8.4e-105 350.2 0.9 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KPA43818.1 - 4.3e-62 209.0 2.3 1.1e-60 204.4 0.2 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region ArAE_1_C PF11728.8 KPA43818.1 - 0.11 12.5 0.2 0.34 10.9 0.2 1.8 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain zf-AN1 PF01428.16 KPA43819.1 - 1.4e-12 47.5 4.2 1.4e-12 47.5 4.2 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger HhH-GPD PF00730.25 KPA43820.1 - 4.9e-18 65.5 0.0 2.2e-17 63.5 0.0 2.0 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KPA43820.1 - 1.4e-06 27.8 0.0 3.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif ADH_N PF08240.12 KPA43821.1 - 1.3e-25 89.4 1.2 1.3e-25 89.4 1.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA43821.1 - 2.2e-20 73.0 0.4 4e-20 72.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KPA43821.1 - 0.0022 17.4 0.8 0.0038 16.5 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KPA43821.1 - 0.0046 17.2 0.0 0.0085 16.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N_2 PF13602.6 KPA43821.1 - 0.0064 17.5 0.0 0.014 16.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPA43821.1 - 0.012 15.1 0.1 0.026 14.0 0.1 1.5 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus IGFBP PF00219.18 KPA43821.1 - 0.021 15.5 0.5 0.072 13.8 0.5 1.9 1 0 0 1 1 1 0 Insulin-like growth factor binding protein UDPG_MGDP_dh_N PF03721.14 KPA43821.1 - 0.032 13.8 0.1 0.054 13.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KPA43821.1 - 0.065 12.6 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1279 PF06916.13 KPA43824.1 - 4.8e-24 84.7 0.0 7.5e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) MARVEL PF01284.23 KPA43826.1 - 1e-20 74.2 13.3 1.2e-20 74.0 13.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF973 PF06157.11 KPA43826.1 - 0.72 8.8 12.7 2.7 7.0 12.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF2208 PF09973.9 KPA43826.1 - 0.94 9.0 3.2 1.4 8.5 3.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF4212 PF13937.6 KPA43826.1 - 4.5 7.7 8.5 26 5.3 5.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4212) DUF485 PF04341.12 KPA43826.1 - 4.5 7.3 7.9 0.79 9.7 3.9 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 PGPGW PF09656.10 KPA43826.1 - 6.8 6.3 9.4 2.3 7.8 3.4 2.5 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) eIF-5_eIF-2B PF01873.17 KPA43828.1 - 9.2e-41 138.4 1.3 1.5e-40 137.7 1.3 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Arc_trans_TRASH PF08394.10 KPA43828.1 - 1.1 9.6 8.4 1 9.8 0.4 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain RR_TM4-6 PF06459.12 KPA43828.1 - 4 7.2 7.4 5.7 6.7 7.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nucleoporin_C PF03177.14 KPA43829.1 - 1.5e-163 545.7 12.1 1.9e-163 545.4 12.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KPA43829.1 - 1.5e-76 257.9 0.0 2e-76 257.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like AFG1_ATPase PF03969.16 KPA43830.1 - 1.1e-54 185.7 0.0 5.9e-27 94.5 0.0 5.0 3 2 1 5 5 5 5 AFG1-like ATPase AAA_16 PF13191.6 KPA43830.1 - 8.7e-05 23.0 0.2 0.022 15.1 0.0 2.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KPA43830.1 - 0.0004 20.4 0.0 0.0012 18.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 KPA43830.1 - 0.00054 19.9 0.1 0.48 10.2 0.0 2.9 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.6 KPA43830.1 - 0.0021 18.4 0.0 0.01 16.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KPA43830.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KPA43830.1 - 0.037 13.8 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KPA43830.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Sedlin_N PF04628.13 KPA43831.1 - 2.1e-12 47.3 0.0 3e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Acyl_transf_1 PF00698.21 KPA43832.1 - 8.8e-21 74.7 0.0 2.7e-18 66.6 0.0 2.1 1 1 0 1 1 1 1 Acyl transferase domain Adap_comp_sub PF00928.21 KPA43833.1 - 2.1e-69 233.8 0.0 2.6e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KPA43833.1 - 0.024 14.5 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain DUF4536 PF15055.6 KPA43834.1 - 1.4e-05 25.2 0.1 2.9e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) ECR1_N PF14382.6 KPA43835.1 - 6.3e-14 51.5 0.2 1.3e-13 50.5 0.2 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KPA43835.1 - 4.2e-05 23.8 0.2 9.7e-05 22.6 0.2 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KPA43835.1 - 0.014 16.0 0.4 0.4 11.3 0.1 2.6 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 Aldedh PF00171.22 KPA43836.1 - 1.2e-77 261.4 0.0 1.4e-77 261.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KPA43836.1 - 2e-05 23.8 0.0 5.1e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) MRP-S28 PF10213.9 KPA43837.1 - 1.3e-46 158.1 0.6 2.6e-46 157.2 0.6 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Ras PF00071.22 KPA43837.1 - 5.2e-05 22.9 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KPA43837.1 - 0.0091 16.2 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF4245 PF14030.6 KPA43837.1 - 0.26 11.3 2.0 9.8 6.2 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) Glyco_tran_28_C PF04101.16 KPA43838.1 - 3.4e-19 69.4 0.0 1.5e-18 67.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KPA43838.1 - 0.0091 14.8 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.6 KPA43838.1 - 0.036 13.3 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 WD40 PF00400.32 KPA43839.1 - 1.4e-30 104.9 21.3 4.1e-05 24.3 0.1 10.7 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA43839.1 - 5.3e-16 58.7 6.7 0.00072 19.8 0.1 6.1 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KPA43839.1 - 2.1e-05 24.3 0.1 2.5 8.2 0.0 3.9 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KPA43839.1 - 0.00052 19.4 0.0 0.051 12.9 0.0 2.8 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 KPA43839.1 - 0.0012 17.9 1.0 3.7 6.4 0.0 3.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KPA43839.1 - 0.0064 16.4 0.6 0.53 10.1 0.1 2.9 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 KPA43839.1 - 0.77 10.3 17.4 5.8 7.5 0.1 6.8 7 1 0 7 7 7 0 PQQ-like domain CFEM PF05730.11 KPA43840.1 - 0.24 11.5 10.7 0.18 11.9 8.7 2.0 1 1 0 1 1 1 0 CFEM domain DUF4691 PF15762.5 KPA43840.1 - 0.34 11.0 9.5 1.6 8.8 3.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4691) TMEM154 PF15102.6 KPA43840.1 - 0.7 9.8 3.7 1.2 9.0 3.7 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF202 PF02656.15 KPA43843.1 - 6.9e-16 58.5 6.9 1.6e-15 57.3 4.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.20 KPA43843.1 - 0.017 14.9 4.5 0.022 14.6 4.5 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Tctex-1 PF03645.13 KPA43844.1 - 8.2e-40 135.2 0.0 9.5e-40 135.0 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family F-box PF00646.33 KPA43845.1 - 0.041 13.8 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 F-box domain F-box-like_2 PF13013.6 KPA43845.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 KPA43845.1 - 0.18 11.7 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 F-box-like SRA PF18491.1 KPA43846.1 - 0.0016 18.5 1.0 0.0049 17.0 1.0 1.8 1 0 0 1 1 1 1 SET and RING associated domain Galactosyl_T PF01762.21 KPA43846.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase SIS PF01380.22 KPA43847.1 - 1.3e-12 47.7 0.0 3.2e-12 46.4 0.0 1.7 1 1 0 1 1 1 1 SIS domain SPX PF03105.19 KPA43848.1 - 2.3e-08 34.4 10.3 0.00014 22.0 0.0 3.0 2 1 0 3 3 3 2 SPX domain Prefoldin_3 PF13758.6 KPA43848.1 - 0.68 10.0 2.3 6.4 6.9 0.6 2.8 2 1 0 2 2 2 0 Prefoldin subunit Fungal_trans PF04082.18 KPA43849.1 - 1.5e-12 47.1 0.0 2.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43849.1 - 7.1e-07 29.3 11.9 1.7e-06 28.1 11.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.25 KPA43850.1 - 4.4e-06 26.9 0.0 5.8e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA43850.1 - 0.00018 21.9 0.0 0.00029 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA43850.1 - 0.00097 19.1 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TMEM239 PF15841.5 KPA43850.1 - 0.038 13.9 1.1 0.11 12.3 0.5 1.9 2 0 0 2 2 2 0 Transmembrane protein 239 family DUF3405 PF11885.8 KPA43853.1 - 2.3e-192 640.2 3.6 3e-192 639.9 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) LIM PF00412.22 KPA43854.1 - 7.6e-22 77.3 19.0 4.2e-11 42.9 5.5 2.9 3 0 0 3 3 3 2 LIM domain WRC PF08879.10 KPA43854.1 - 0.0086 15.7 1.2 0.12 12.0 0.4 2.4 2 0 0 2 2 2 1 WRC NAD_binding_5 PF07994.12 KPA43855.1 - 2.6e-147 490.4 0.2 3e-147 490.2 0.2 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KPA43855.1 - 1.1e-45 154.3 0.6 2.6e-45 153.1 0.6 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase MRC1 PF09444.10 KPA43856.1 - 1.6e-43 148.7 18.9 1.6e-43 148.7 18.9 8.4 6 2 3 10 10 10 1 MRC1-like domain ABC1 PF03109.16 KPA43857.1 - 1.1e-31 109.5 0.0 1.9e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Snurportin1 PF11538.8 KPA43858.1 - 0.13 12.4 8.3 0.33 11.2 8.3 1.7 1 0 0 1 1 1 0 Snurportin1 DUF433 PF04255.14 KPA43858.1 - 0.15 12.0 0.0 0.55 10.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF433) DUF4375 PF14300.6 KPA43858.1 - 0.27 11.5 2.4 0.6 10.4 2.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4375) Pex19 PF04614.12 KPA43859.1 - 3.1e-75 253.1 12.9 3.1e-75 253.1 12.9 2.5 2 1 0 2 2 2 1 Pex19 protein family PP2C_C PF07830.13 KPA43859.1 - 1.3 9.6 12.6 2.4 8.7 0.1 4.4 4 0 0 4 4 4 0 Protein serine/threonine phosphatase 2C, C-terminal domain UQ_con PF00179.26 KPA43860.1 - 2e-49 166.8 0.0 2.3e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPA43860.1 - 2.1e-06 27.5 0.0 2.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KPA43860.1 - 0.034 14.4 1.4 0.067 13.5 1.4 1.7 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.21 KPA43861.1 - 3.5e-92 309.8 0.1 1.3e-52 179.7 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KPA43861.1 - 7.9e-38 129.1 0.0 1.3e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KPA43861.1 - 1.1e-29 103.3 0.0 1.8e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KPA43861.1 - 5.4e-09 35.8 0.0 1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KPA43861.1 - 0.0022 17.2 0.0 0.0057 15.8 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Porin_3 PF01459.22 KPA43862.1 - 7.8e-71 238.7 5.6 8.7e-71 238.5 5.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.31 KPA43863.1 - 3.2e-12 46.4 0.1 6.5e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_47 PF01532.20 KPA43864.1 - 1.7e-165 551.3 0.1 2e-165 551.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 UPF1_Zn_bind PF09416.10 KPA43865.1 - 1.1e-69 233.3 2.0 1.1e-69 233.3 2.0 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KPA43865.1 - 3.7e-60 203.0 0.0 1.5e-59 201.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KPA43865.1 - 3.5e-54 184.3 2.4 3.9e-31 108.8 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KPA43865.1 - 2e-31 108.1 0.0 4.6e-31 106.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KPA43865.1 - 4.1e-13 49.5 0.2 4.3e-12 46.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPA43865.1 - 2.4e-10 40.9 0.1 8.7e-10 39.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KPA43865.1 - 4.5e-06 26.8 0.0 8.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KPA43865.1 - 6.6e-05 22.8 0.1 0.37 10.5 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KPA43865.1 - 6.9e-05 22.8 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 KPA43865.1 - 0.00032 20.0 0.6 0.007 15.6 0.1 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KPA43865.1 - 0.00048 19.4 0.3 0.26 10.4 0.1 2.3 1 1 0 2 2 2 2 PIF1-like helicase ATPase PF06745.13 KPA43865.1 - 0.00081 18.8 0.0 0.0057 16.0 0.0 2.1 2 0 0 2 2 2 1 KaiC DEAD PF00270.29 KPA43865.1 - 0.0012 18.6 0.2 0.0022 17.8 0.2 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KPA43865.1 - 0.0014 18.2 0.0 0.036 13.6 0.0 2.3 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_10 PF12846.7 KPA43865.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.22 KPA43865.1 - 0.025 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KPA43865.1 - 0.13 12.5 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KPA43865.1 - 0.14 11.6 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 KPA43865.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Brix PF04427.18 KPA43866.1 - 1.5e-30 106.8 0.0 1.9e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain Syntaxin PF00804.25 KPA43867.1 - 2.4e-23 82.9 7.2 3.6e-23 82.3 7.2 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KPA43867.1 - 4.8e-10 39.3 0.4 1.4e-09 37.8 0.4 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KPA43867.1 - 0.0099 16.2 8.0 0.0099 16.2 8.0 2.7 2 1 0 2 2 2 1 Syntaxin-like protein TMCO5 PF14992.6 KPA43867.1 - 0.05 13.2 6.8 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 TMCO5 family MCU PF04678.13 KPA43867.1 - 0.084 13.0 8.3 0.29 11.2 8.3 2.1 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Tli4_N PF18443.1 KPA43867.1 - 0.6 10.5 6.8 0.32 11.3 3.9 1.9 1 1 1 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain DUF4094 PF13334.6 KPA43867.1 - 1.1 9.7 7.2 3.6 8.1 0.1 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) Mito_fiss_reg PF05308.11 KPA43867.1 - 1.3 9.0 9.1 4.4 7.3 3.9 2.3 1 1 0 2 2 2 0 Mitochondrial fission regulator Allexi_40kDa PF05549.11 KPA43867.1 - 1.7 8.1 8.1 0.3 10.6 1.7 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein SLATT_1 PF18181.1 KPA43867.1 - 6.1 6.8 10.3 1 9.3 0.3 2.8 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Efg1 PF10153.9 KPA43867.1 - 6.9 7.1 10.6 7.4 7.0 1.3 2.8 3 0 0 3 3 3 0 rRNA-processing protein Efg1 Prominin PF05478.11 KPA43867.1 - 7.7 4.3 10.7 7.5 4.4 3.0 2.5 2 1 1 3 3 3 0 Prominin TPR_1 PF00515.28 KPA43868.1 - 1e-44 148.6 17.8 7.7e-06 25.5 0.1 11.5 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 KPA43868.1 - 2.2e-43 142.9 18.6 3e-05 23.8 0.1 11.6 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_17 PF13431.6 KPA43868.1 - 1.2e-27 94.3 6.0 2.5e-05 24.3 0.0 9.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 KPA43868.1 - 6e-27 91.6 19.5 0.00023 21.1 0.0 10.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 KPA43868.1 - 2e-25 89.1 4.8 5e-07 30.3 0.2 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 KPA43868.1 - 1.7e-20 72.4 14.8 3.7e-05 23.3 0.0 8.8 6 1 2 8 8 8 4 TPR repeat TPR_19 PF14559.6 KPA43868.1 - 1.9e-19 69.9 16.5 2e-05 25.0 0.4 7.3 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPA43868.1 - 1.7e-18 66.7 23.3 0.0013 19.0 0.8 8.6 3 3 7 10 10 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 KPA43868.1 - 7.1e-16 57.5 12.4 0.00088 19.9 0.2 9.5 4 2 6 10 10 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KPA43868.1 - 1.1e-13 51.1 3.6 0.0013 18.9 0.0 6.1 3 2 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPA43868.1 - 3.2e-10 39.3 16.6 0.3 11.2 0.1 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 KPA43868.1 - 4.8e-08 32.6 16.2 0.61 10.0 0.3 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KPA43868.1 - 8e-07 28.7 1.9 2.9e-05 23.6 0.8 2.8 1 1 0 1 1 1 1 MalT-like TPR region SHNi-TPR PF10516.9 KPA43868.1 - 5.5e-05 22.5 6.9 0.069 12.6 0.0 5.2 5 0 0 5 5 5 1 SHNi-TPR TPR_6 PF13174.6 KPA43868.1 - 0.00019 21.9 22.7 0.2 12.3 0.0 9.0 10 0 0 10 10 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA43868.1 - 0.0002 21.5 12.9 0.68 10.2 0.0 5.8 2 2 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KPA43868.1 - 0.0016 17.4 0.7 0.032 13.2 0.3 4.4 3 2 2 5 5 5 2 NMDA receptor-regulated protein 1 DUF4675 PF15720.5 KPA43868.1 - 0.018 14.8 0.8 1.4 8.7 0.4 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4675) Sel1 PF08238.12 KPA43868.1 - 0.019 15.7 5.7 2.2 9.1 0.2 4.5 4 0 0 4 4 3 0 Sel1 repeat PknG_TPR PF16918.5 KPA43868.1 - 0.02 13.6 0.0 0.079 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat DUF3856 PF12968.7 KPA43868.1 - 0.021 14.9 5.5 9.3 6.3 0.1 5.2 4 3 0 4 4 4 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 KPA43868.1 - 0.028 14.5 12.3 27 4.9 0.1 6.4 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Rrn6 PF10214.9 KPA43868.1 - 0.039 12.4 0.9 0.061 11.8 0.2 1.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor MAS20 PF02064.15 KPA43868.1 - 0.13 12.3 13.3 0.14 12.3 0.2 4.7 5 1 1 6 6 5 0 MAS20 protein import receptor Coatomer_E PF04733.14 KPA43868.1 - 0.3 10.5 7.7 0.66 9.3 0.1 3.8 3 2 1 4 4 4 0 Coatomer epsilon subunit BTAD PF03704.17 KPA43868.1 - 0.4 11.1 5.3 19 5.7 0.1 4.5 2 2 1 4 4 4 0 Bacterial transcriptional activator domain Aminotran_4 PF01063.19 KPA43869.1 - 6.4e-22 78.5 0.0 1.1e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV F-box PF00646.33 KPA43870.1 - 1.3e-09 37.7 0.0 4.1e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KPA43870.1 - 2e-09 37.2 0.2 5.1e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KPA43870.1 - 0.16 12.5 9.7 9.1 6.9 0.5 5.8 4 1 4 8 8 8 0 Leucine Rich repeats (2 copies) TPR_1 PF00515.28 KPA43870.1 - 0.6 10.0 2.5 3.3 7.7 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPA43870.1 - 2.6 8.4 5.4 26 5.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MMR_HSR1_C PF08438.10 KPA43871.1 - 1.1e-36 125.8 0.0 2.1e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KPA43871.1 - 5.7e-21 74.7 0.0 2.1e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPA43871.1 - 9.4e-09 35.0 0.1 2.8e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KPA43871.1 - 0.0031 17.6 0.7 0.089 12.8 0.2 2.6 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 KPA43871.1 - 0.0083 15.7 0.3 0.38 10.3 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPA43871.1 - 0.034 14.1 0.4 3.6 7.5 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase MDH PF02315.16 KPA43871.1 - 0.15 12.1 0.2 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit SET PF00856.28 KPA43872.1 - 0.00011 22.6 0.0 0.00024 21.5 0.0 1.5 1 1 0 1 1 1 1 SET domain Pentapeptide PF00805.22 KPA43872.1 - 0.17 11.5 0.0 0.75 9.5 0.0 1.9 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) Fungal_trans PF04082.18 KPA43873.1 - 1.7e-36 125.7 1.5 2.6e-36 125.0 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43873.1 - 2.8e-10 40.1 11.1 5e-10 39.3 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MetOD2 PF18548.1 KPA43873.1 - 0.057 13.5 0.8 4.1 7.6 0.0 3.2 3 0 0 3 3 3 0 Metanogen output domain 2 bZIP_1 PF00170.21 KPA43873.1 - 0.11 12.6 0.7 0.3 11.2 0.7 1.8 1 0 0 1 1 1 0 bZIP transcription factor GDPD PF03009.17 KPA43874.1 - 4.7e-18 65.9 0.4 9e-16 58.4 0.0 2.6 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Plus-3 PF03126.18 KPA43875.1 - 3e-24 85.6 0.0 1.6e-23 83.3 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain Rnk_N PF14760.6 KPA43875.1 - 0.053 14.0 6.3 0.26 11.8 6.3 2.3 1 0 0 1 1 1 0 Rnk N-terminus COQ7 PF03232.13 KPA43876.1 - 2.8e-71 238.8 1.9 3.7e-71 238.4 1.9 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KPA43876.1 - 0.00025 21.5 0.0 0.00057 20.3 0.0 1.6 1 1 0 1 1 1 1 Rubrerythrin PLDc PF00614.22 KPA43877.1 - 6.7e-18 64.1 0.4 4.2e-08 33.0 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KPA43877.1 - 1.6e-12 47.5 0.0 1.6e-06 28.0 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 KPA43877.1 - 9.8e-08 32.0 0.0 7.8e-07 29.1 0.0 2.5 2 1 0 2 2 2 1 PX domain PGA2 PF07543.12 KPA43877.1 - 0.01 15.8 1.7 0.01 15.8 1.7 2.9 3 0 0 3 3 3 0 Protein trafficking PGA2 p450 PF00067.22 KPA43878.1 - 1.1e-48 166.2 0.0 4.5e-48 164.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Rho_N PF07498.12 KPA43879.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain DUF3405 PF11885.8 KPA43880.1 - 3.7e-203 675.8 4.5 7e-202 671.6 4.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Adaptin_N PF01602.20 KPA43881.1 - 8.3e-142 473.4 1.4 9.8e-142 473.2 1.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KPA43881.1 - 4.2e-23 81.8 0.1 1.5e-22 80.0 0.1 2.0 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KPA43881.1 - 2.9e-08 33.9 5.1 0.00057 20.0 0.0 4.4 2 2 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3730 PF12530.8 KPA43881.1 - 3.7e-05 23.4 0.0 0.00027 20.6 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3730) HEAT_2 PF13646.6 KPA43881.1 - 5.3e-05 23.5 2.1 0.28 11.6 0.0 3.6 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KPA43881.1 - 0.011 15.9 1.1 6.4 7.3 0.1 4.4 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 KPA43881.1 - 0.063 13.8 0.6 64 4.2 0.0 4.7 4 1 1 5 5 5 0 HEAT-like repeat NAD_binding_1 PF00175.21 KPA43882.1 - 1.1e-08 35.7 0.0 1.5e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KPA43882.1 - 0.0013 18.8 0.0 0.41 10.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NCBP3 PF10309.9 KPA43883.1 - 1.1e-21 76.4 0.0 1.9e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 V_ATPase_I PF01496.19 KPA43884.1 - 0.032 12.2 3.4 0.044 11.7 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF812 PF05667.11 KPA43884.1 - 0.046 12.6 11.8 0.063 12.2 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) KASH_CCD PF14662.6 KPA43884.1 - 0.25 11.1 14.3 0.46 10.3 14.3 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HXXSHH PF07586.11 KPA43884.1 - 0.56 9.7 4.1 1.1 8.8 4.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1552) Exonuc_VII_L PF02601.15 KPA43884.1 - 0.64 9.5 8.5 1 8.9 8.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SRP_TPR_like PF17004.5 KPA43886.1 - 5.2e-25 87.7 1.0 1.9e-22 79.5 0.4 2.5 2 0 0 2 2 2 2 Putative TPR-like repeat SRP72 PF08492.12 KPA43886.1 - 1.9e-17 63.4 5.9 1.9e-17 63.4 5.9 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_14 PF13428.6 KPA43886.1 - 2.9e-07 30.7 26.0 0.014 16.2 0.3 7.7 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPA43886.1 - 6.8e-07 28.9 18.8 0.71 10.1 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KPA43886.1 - 1.4e-06 28.7 28.7 0.023 15.2 0.3 6.7 4 2 3 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA43886.1 - 0.00039 20.6 12.0 0.0036 17.5 1.4 4.3 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KPA43886.1 - 0.0028 17.6 4.8 2.2 8.3 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR PF01535.20 KPA43886.1 - 0.01 16.0 0.0 3.9 7.9 0.0 4.0 5 0 0 5 5 4 0 PPR repeat TPR_11 PF13414.6 KPA43886.1 - 0.019 14.6 7.8 3.3 7.5 0.1 4.6 4 0 0 4 4 4 0 TPR repeat TPR_6 PF13174.6 KPA43886.1 - 0.069 13.8 10.2 8.3 7.3 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KPA43886.1 - 0.15 12.2 10.9 2.6 8.3 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KPA43886.1 - 0.16 12.3 14.1 7.6 6.9 0.1 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPA43886.1 - 0.21 11.5 13.2 1.1 9.2 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KPA43886.1 - 0.26 11.6 13.4 4 7.9 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPA43886.1 - 0.43 11.3 21.0 5.3 7.8 1.8 6.4 5 1 3 8 8 7 0 Tetratricopeptide repeat Sec7 PF01369.20 KPA43887.1 - 2.7e-30 105.4 0.1 4.4e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KPA43887.1 - 7.2e-06 26.5 0.0 2.1e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KPA43887.1 - 3.5e-05 24.1 0.1 8.2e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain SMAP PF15477.6 KPA43887.1 - 2.8 8.9 7.6 1.1e+02 3.8 0.1 4.8 5 0 0 5 5 5 0 Small acidic protein family TFIIE_alpha PF02002.17 KPA43888.1 - 4.9e-14 52.1 0.3 1.1e-13 51.0 0.3 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit CDC27 PF09507.10 KPA43888.1 - 0.029 13.8 22.0 0.037 13.4 22.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-Dof PF02701.15 KPA43888.1 - 0.057 13.6 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Dof domain, zinc finger Pinin_SDK_N PF04697.13 KPA43888.1 - 5.2 7.7 11.7 0.45 11.2 2.6 2.6 1 1 0 2 2 2 0 pinin/SDK conserved region DNA_pol_B_thumb PF14791.6 KPA43889.1 - 5.5e-21 74.5 0.0 1.5e-20 73.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KPA43889.1 - 5e-19 68.6 0.0 8.9e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KPA43889.1 - 6.3e-10 38.7 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KPA43889.1 - 3.3e-06 27.4 0.0 5.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 KPA43889.1 - 0.038 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain NTP_transf_2 PF01909.23 KPA43889.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Epimerase_2 PF02350.19 KPA43889.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase MAPEG PF01124.18 KPA43890.1 - 1.5e-20 73.4 0.3 1.8e-20 73.2 0.3 1.1 1 0 0 1 1 1 1 MAPEG family Peptidase_M14 PF00246.24 KPA43891.1 - 2.5e-74 250.7 0.0 3.2e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF956 PF06115.11 KPA43891.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF956) RRM_1 PF00076.22 KPA43892.1 - 1.5e-20 72.8 0.0 2.1e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPA43892.1 - 6e-05 22.6 0.0 8.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short_C2 PF13561.6 KPA43893.1 - 2.4e-57 194.2 3.8 2.9e-57 193.9 3.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA43893.1 - 2.4e-42 144.6 3.6 3e-42 144.3 3.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA43893.1 - 2.2e-12 47.3 3.1 2.9e-12 46.9 3.1 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox_dim PF02852.22 KPA43893.1 - 0.086 13.1 0.3 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Acetyltransf_10 PF13673.7 KPA43894.1 - 5.2e-09 36.1 0.0 8.2e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA43894.1 - 1.1e-08 35.4 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KPA43894.1 - 1.2e-06 28.4 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KPA43894.1 - 6.2e-06 26.6 0.0 8.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA43894.1 - 0.00072 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MarR_2 PF12802.7 KPA43895.1 - 0.042 13.7 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 MarR family Tape_meas_lam_C PF09718.10 KPA43895.1 - 0.22 11.7 0.9 38 4.5 0.0 2.9 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) WD40 PF00400.32 KPA43896.1 - 2.8e-19 69.1 16.5 0.00039 21.2 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA43896.1 - 5.1e-14 52.3 5.7 1.6e-05 25.1 0.4 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPA43896.1 - 3.9e-07 30.2 0.1 0.0009 19.2 0.1 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Orthopox_A5L PF06193.11 KPA43896.1 - 1.9 7.9 5.6 3.8 6.9 5.6 1.5 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like DUF2838 PF10998.8 KPA43897.1 - 6.4e-45 151.9 8.3 6.4e-45 151.9 8.3 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) ApoLp-III PF07464.11 KPA43897.1 - 0.011 15.8 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF5023 PF16426.5 KPA43897.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5023) DUF3782 PF12644.7 KPA43897.1 - 0.077 13.1 1.9 0.11 12.7 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) DUF3584 PF12128.8 KPA43897.1 - 0.67 7.4 3.7 0.98 6.8 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DHR10 PF18595.1 KPA43897.1 - 7.3 6.7 10.0 9.2 6.4 3.7 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain SMC_N PF02463.19 KPA43898.1 - 9.3e-35 120.0 28.2 3.7e-34 118.1 28.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KPA43898.1 - 7.7e-26 90.7 0.0 5.2e-25 88.0 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain FPP PF05911.11 KPA43898.1 - 1.3e-06 27.0 88.3 0.00051 18.4 43.3 4.2 4 0 0 4 4 4 4 Filament-like plant protein, long coiled-coil AAA_21 PF13304.6 KPA43898.1 - 0.0004 20.3 0.0 0.0004 20.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 KPA43898.1 - 0.00042 18.0 44.8 0.00042 18.0 44.8 4.8 3 2 1 5 5 5 2 Protein of unknown function (DUF3584) Spc7 PF08317.11 KPA43898.1 - 0.0012 17.8 118.5 0.033 13.1 12.0 7.1 3 2 4 7 7 7 5 Spc7 kinetochore protein MAD PF05557.13 KPA43898.1 - 0.0016 17.0 19.3 0.0016 17.0 19.3 5.1 4 1 1 5 5 5 2 Mitotic checkpoint protein SlyX PF04102.12 KPA43898.1 - 0.0066 17.0 3.7 0.0066 17.0 3.7 9.6 7 3 1 8 8 8 1 SlyX Filament PF00038.21 KPA43898.1 - 0.0098 15.5 3.4 0.0098 15.5 3.4 7.2 3 2 4 7 7 7 1 Intermediate filament protein SbcCD_C PF13558.6 KPA43898.1 - 0.014 15.6 0.0 0.091 13.0 0.0 2.5 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit TrbI_Ftype PF09677.10 KPA43898.1 - 0.17 12.2 6.7 3.7 7.9 0.6 3.6 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) TRAF_BIRC3_bd PF16673.5 KPA43898.1 - 0.25 11.2 0.0 0.25 11.2 0.0 7.5 8 0 0 8 8 7 0 TNF receptor-associated factor BIRC3 binding domain ATG16 PF08614.11 KPA43898.1 - 0.58 10.4 115.7 0.51 10.5 13.1 6.9 4 3 2 6 6 6 0 Autophagy protein 16 (ATG16) WEMBL PF05701.11 KPA43898.1 - 1.2 7.7 94.9 0.24 10.1 1.2 5.4 4 1 1 5 5 5 0 Weak chloroplast movement under blue light Sec39 PF08314.11 KPA43899.1 - 6.2e-272 904.5 0.0 7.5e-272 904.2 0.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.9 KPA43900.1 - 0.00024 21.3 0.0 0.00033 20.8 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KPA43900.1 - 0.05 14.0 0.9 0.15 12.5 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) DUF3859 PF12975.7 KPA43901.1 - 0.0038 17.2 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3859) CTK3_C PF12350.8 KPA43902.1 - 0.032 14.4 1.0 0.032 14.4 1.0 2.2 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus Myb_DNA-binding PF00249.31 KPA43903.1 - 3.2e-26 91.2 2.7 2.7e-14 53.1 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPA43903.1 - 2.3e-17 63.0 2.4 5.4e-13 49.0 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KPA43903.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 SLIDE HTH_23 PF13384.6 KPA43903.1 - 0.082 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Glyco_transf_41 PF13844.6 KPA43904.1 - 1e-99 334.1 0.0 1.8e-49 168.5 0.0 3.4 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KPA43904.1 - 1.2e-21 75.5 4.3 0.0011 18.7 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KPA43904.1 - 2.2e-17 61.7 4.2 0.011 15.7 0.0 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KPA43904.1 - 5.6e-13 48.3 7.3 0.0045 16.7 0.1 6.4 3 2 3 6 6 6 3 TPR repeat TPR_8 PF13181.6 KPA43904.1 - 4.2e-12 45.3 2.9 0.017 15.3 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KPA43904.1 - 2e-11 43.5 0.2 0.037 14.4 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KPA43904.1 - 2.2e-09 36.9 7.8 0.031 14.1 0.1 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPA43904.1 - 1.1e-08 35.2 9.1 0.058 13.7 0.5 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KPA43904.1 - 5.7e-07 30.1 0.5 1.7 9.3 0.0 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KPA43904.1 - 7.4e-07 29.6 2.7 0.021 15.3 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KPA43904.1 - 1.3e-06 28.7 0.3 4.8 8.3 0.0 5.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPA43904.1 - 5.5e-06 26.0 1.0 0.18 11.9 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 KPA43904.1 - 0.0028 18.1 0.4 0.45 11.0 0.0 3.1 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 KPA43904.1 - 0.0073 16.4 1.5 2.5 8.3 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA43904.1 - 0.079 13.2 0.3 1.3 9.3 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KPA43904.1 - 0.27 11.3 2.5 17 5.5 0.0 3.9 2 2 1 3 3 3 0 MIT (microtubule interacting and transport) domain Ribosomal_L11_N PF03946.14 KPA43905.1 - 2.8e-25 87.9 0.2 4.4e-25 87.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KPA43905.1 - 2e-16 60.2 0.2 3.6e-16 59.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Met_asp_mut_E PF06368.11 KPA43905.1 - 0.021 13.4 0.2 0.026 13.0 0.2 1.0 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Sec23_trunk PF04811.15 KPA43906.1 - 3e-79 266.1 0.0 4.1e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KPA43906.1 - 1.3e-30 106.0 0.1 2.6e-30 105.0 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KPA43906.1 - 1.8e-25 88.7 0.1 4.8e-25 87.4 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KPA43906.1 - 1.5e-15 56.9 6.4 2.7e-15 56.1 6.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KPA43906.1 - 8.1e-12 44.9 0.0 2.2e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KPA43906.1 - 0.054 12.9 0.3 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain 2_5_RNA_ligase2 PF13563.6 KPA43907.1 - 1e-33 116.4 0.9 2.9e-33 114.9 0.9 1.8 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MJ1316 PF04457.12 KPA43907.1 - 4e-19 69.1 1.2 1.1e-18 67.7 1.2 1.8 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain PAP_central PF04928.17 KPA43907.1 - 4e-15 55.5 0.0 7.5e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.23 KPA43907.1 - 1.6e-06 27.8 0.0 5.3e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 KPA43907.1 - 0.00017 21.8 0.0 0.00046 20.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain AKAP7_NLS PF10469.9 KPA43907.1 - 0.0035 17.2 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 KPA43907.1 - 0.07 13.3 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 LigT like Phosphoesterase GPW_gp25 PF04965.14 KPA43907.1 - 0.085 12.6 0.0 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 Gene 25-like lysozyme PAP_RNA-bind PF04926.15 KPA43907.1 - 0.11 12.1 0.0 0.41 10.3 0.0 1.9 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain Exo70 PF03081.15 KPA43908.1 - 8.6e-87 291.6 0.0 2.3e-86 290.2 0.0 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Sec8_exocyst PF04048.14 KPA43908.1 - 0.015 15.2 0.3 1.9 8.4 0.0 3.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Apolipoprotein PF01442.18 KPA43908.1 - 0.25 11.2 7.3 0.55 10.1 0.2 3.2 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KPA43908.1 - 0.49 10.4 7.1 39 4.3 0.0 3.9 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.9 KPA43908.1 - 0.66 10.7 4.1 0.49 11.1 0.2 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) MCM PF00493.23 KPA43909.1 - 1.6e-97 325.0 0.1 2.8e-97 324.2 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KPA43909.1 - 2.3e-29 101.8 0.0 4.6e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KPA43909.1 - 2e-23 82.6 0.3 4.2e-23 81.6 0.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KPA43909.1 - 8.3e-13 48.8 0.0 2.4e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KPA43909.1 - 2.8e-07 30.1 0.0 3.2e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KPA43909.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KPA43909.1 - 0.011 15.4 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 KPA43909.1 - 0.069 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TFIIF_alpha PF05793.12 KPA43909.1 - 2.1 6.8 14.8 3.2 6.2 14.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PfkB PF00294.24 KPA43910.1 - 7.5e-14 51.7 0.0 3.1e-08 33.3 0.1 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Trypan_PARP PF05887.11 KPA43910.1 - 0.6 10.1 20.4 0.12 12.3 16.5 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CAP_N PF01213.19 KPA43911.1 - 1.6e-123 412.2 0.3 2.7e-123 411.5 0.3 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KPA43911.1 - 2.8e-56 189.5 3.1 4e-56 189.0 3.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DEC-1_N PF04625.13 KPA43911.1 - 0.17 10.9 19.0 0.11 11.5 2.8 2.3 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Carn_acyltransf PF00755.20 KPA43912.1 - 9.2e-211 701.5 0.0 1.1e-210 701.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Phycobilisome PF00502.19 KPA43912.1 - 0.052 13.5 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Phycobilisome protein SWIRM PF04433.17 KPA43913.1 - 3.6e-32 110.6 0.2 7.5e-32 109.5 0.2 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KPA43913.1 - 8e-31 105.9 4.4 1.9e-30 104.6 4.4 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KPA43913.1 - 7.5e-10 38.9 0.0 2.1e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPA43913.1 - 2.4e-05 24.5 0.1 6.3e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KPA43913.1 - 0.0037 17.1 9.1 0.0096 15.7 9.1 1.7 1 1 0 1 1 1 1 Zinc finger, ZZ type UPF0167 PF03691.14 KPA43913.1 - 0.064 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) DUF3439 PF11921.8 KPA43913.1 - 0.17 11.8 2.1 0.45 10.5 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ETF PF01012.21 KPA43914.1 - 2.2e-42 145.0 2.7 3.7e-42 144.3 2.7 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KPA43914.1 - 4.8e-34 116.3 0.1 1.2e-33 114.9 0.1 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Pyr_redox_2 PF07992.14 KPA43915.1 - 0.0001 21.7 0.0 0.0027 17.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PFK PF00365.20 KPA43915.1 - 0.0015 18.0 0.0 0.016 14.5 0.0 2.0 2 0 0 2 2 2 1 Phosphofructokinase Asp_Glu_race PF01177.22 KPA43915.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase MutL_C PF08676.11 KPA43918.1 - 6.2e-20 71.5 0.1 1.5e-19 70.2 0.1 1.7 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KPA43918.1 - 9e-19 67.3 0.0 2.4e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KPA43918.1 - 7.2e-12 45.3 0.0 2.3e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KPA43918.1 - 1.7e-06 28.5 0.0 3.9e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGAP1 PF07819.13 KPA43919.1 - 1e-92 310.1 0.0 1.5e-92 309.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KPA43919.1 - 7e-06 26.8 0.1 1.7e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA43919.1 - 0.0018 17.9 0.0 0.0057 16.3 0.0 1.9 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 KPA43919.1 - 0.0021 17.9 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 KPA43919.1 - 0.0041 16.4 0.0 0.0083 15.4 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KPA43919.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF1883 PF08980.10 KPA43919.1 - 0.053 13.5 0.0 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1883) LCAT PF02450.15 KPA43919.1 - 0.058 12.6 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Esterase PF00756.20 KPA43919.1 - 0.068 12.8 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Lipase_3 PF01764.25 KPA43919.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) COesterase PF00135.28 KPA43919.1 - 0.24 10.2 0.0 0.34 9.7 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family MFS_1 PF07690.16 KPA43920.1 - 2.6e-14 52.9 9.2 2.6e-14 52.9 9.2 3.0 2 1 0 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KPA43920.1 - 1.3e-12 47.7 2.4 1.3e-12 47.7 2.4 2.1 2 0 0 2 2 2 1 Nodulin-like MFS_3 PF05977.13 KPA43920.1 - 0.23 9.8 3.5 0.1 11.0 0.7 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2207 PF09972.9 KPA43920.1 - 9.2 4.9 6.0 1.9 7.1 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Serinc PF03348.15 KPA43921.1 - 1.7e-158 528.0 12.5 2e-158 527.9 12.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Cys_Met_Meta_PP PF01053.20 KPA43922.1 - 2.8e-138 460.6 0.0 3.2e-138 460.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KPA43922.1 - 2.5e-07 30.0 0.0 6.5e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KPA43922.1 - 3.6e-07 29.7 0.0 6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KPA43922.1 - 6.9e-05 22.3 0.1 0.00022 20.6 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KPA43922.1 - 0.0005 18.7 0.1 0.0023 16.6 0.1 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase ZFYVE21_C PF16696.5 KPA43922.1 - 0.015 15.2 0.0 0.86 9.5 0.0 2.5 2 0 0 2 2 2 0 Zinc finger FYVE domain-containing protein 21 C-terminus Beta_elim_lyase PF01212.21 KPA43922.1 - 0.06 12.6 0.1 0.15 11.3 0.1 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase AAA PF00004.29 KPA43923.1 - 6.5e-38 130.1 0.0 1e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA43923.1 - 1.7e-07 30.9 0.0 3.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KPA43923.1 - 5.1e-06 27.0 0.1 0.00036 21.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KPA43923.1 - 7e-06 26.1 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KPA43923.1 - 8.6e-06 25.6 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KPA43923.1 - 1.1e-05 25.7 0.3 0.002 18.4 0.1 3.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 KPA43923.1 - 4.3e-05 23.5 0.2 0.00039 20.4 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KPA43923.1 - 9.1e-05 22.6 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 KPA43923.1 - 0.0011 18.4 0.1 2.2 7.7 0.0 2.8 2 1 0 3 3 3 2 Bacterial TniB protein Mg_chelatase PF01078.21 KPA43923.1 - 0.0016 17.8 0.1 0.0037 16.7 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KPA43923.1 - 0.0021 17.8 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KPA43923.1 - 0.0036 17.5 0.0 0.0075 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KPA43923.1 - 0.0043 16.6 0.2 0.069 12.7 0.1 2.5 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KPA43923.1 - 0.0064 16.9 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KPA43923.1 - 0.0089 16.6 0.0 0.043 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KPA43923.1 - 0.0094 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KPA43923.1 - 0.012 14.8 0.0 0.17 11.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 KPA43923.1 - 0.012 14.7 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KPA43923.1 - 0.014 15.2 0.0 0.033 13.9 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KPA43923.1 - 0.017 15.0 0.0 0.13 12.1 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 KPA43923.1 - 0.03 14.3 0.1 0.08 12.9 0.1 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KPA43923.1 - 0.032 14.3 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 KPA43923.1 - 0.035 13.8 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KPA43923.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KPA43923.1 - 0.056 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KPA43923.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 KPA43923.1 - 0.075 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Oxidored_nitro PF00148.19 KPA43923.1 - 0.075 11.8 0.0 0.78 8.4 0.0 2.0 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase TsaE PF02367.17 KPA43923.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KPA43923.1 - 0.09 13.3 0.0 0.2 12.2 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Bac_DnaA PF00308.18 KPA43923.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 KPA43923.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 KPA43923.1 - 0.14 12.6 0.6 0.33 11.4 0.1 1.9 2 0 0 2 2 1 0 AAA domain Csm1 PF12539.8 KPA43924.1 - 2.7e-31 108.0 0.1 5.2e-31 107.1 0.1 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 EzrA PF06160.12 KPA43924.1 - 4.7e-05 21.8 6.9 7.4e-05 21.1 6.9 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Spc7 PF08317.11 KPA43924.1 - 0.0032 16.4 12.1 0.0052 15.7 12.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.9 KPA43924.1 - 0.0074 15.4 10.9 0.01 14.9 10.9 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Rootletin PF15035.6 KPA43924.1 - 0.014 15.5 13.8 0.033 14.2 13.8 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.12 KPA43924.1 - 0.022 14.8 3.2 0.041 13.9 3.2 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 KPA43924.1 - 0.025 12.6 2.3 0.033 12.2 2.3 1.2 1 0 0 1 1 1 0 Prominin DUF445 PF04286.12 KPA43924.1 - 0.032 14.0 4.7 0.044 13.6 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HIP1_clath_bdg PF16515.5 KPA43924.1 - 0.034 14.7 15.7 0.16 12.6 12.5 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4201 PF13870.6 KPA43924.1 - 0.047 13.4 9.9 0.075 12.8 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) THOC7 PF05615.13 KPA43924.1 - 0.049 13.9 15.9 0.24 11.7 3.2 2.7 1 1 1 2 2 2 0 Tho complex subunit 7 USP8_interact PF08941.10 KPA43924.1 - 0.049 13.4 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 USP8 interacting DUF3584 PF12128.8 KPA43924.1 - 0.05 11.1 15.1 0.068 10.7 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sipho_Gp157 PF05565.11 KPA43924.1 - 0.07 13.1 9.3 0.14 12.2 9.3 1.5 1 0 0 1 1 1 0 Siphovirus Gp157 DUF5094 PF17015.5 KPA43924.1 - 0.077 13.1 4.8 0.3 11.2 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5094) Jnk-SapK_ap_N PF09744.9 KPA43924.1 - 0.078 13.2 11.6 0.15 12.3 11.6 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Phlebovirus_NSM PF07246.11 KPA43924.1 - 0.083 12.3 3.4 0.14 11.5 3.4 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AAA_13 PF13166.6 KPA43924.1 - 0.24 10.0 9.2 0.35 9.4 9.2 1.2 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.9 KPA43924.1 - 0.35 11.2 9.7 1.1 9.6 8.7 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 KPA43924.1 - 0.42 8.5 7.4 0.55 8.1 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KPA43924.1 - 0.46 10.5 4.0 0.97 9.5 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KPA43924.1 - 0.48 11.1 7.4 5 7.8 0.1 3.5 1 1 2 3 3 3 0 SlyX APG6_N PF17675.1 KPA43924.1 - 0.54 10.8 18.1 1 9.9 18.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Fez1 PF06818.15 KPA43924.1 - 0.56 10.6 16.5 1.5 9.3 16.5 1.6 1 1 0 1 1 1 0 Fez1 Nup88 PF10168.9 KPA43924.1 - 0.57 7.9 8.5 0.88 7.3 8.5 1.2 1 0 0 1 1 1 0 Nuclear pore component Cauli_AT PF03233.13 KPA43924.1 - 0.76 9.7 4.1 1.5 8.7 4.1 1.4 1 0 0 1 1 1 0 Aphid transmission protein CHDCT2 PF08074.11 KPA43924.1 - 0.82 9.8 4.1 1.4 9.0 4.1 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain CREPT PF16566.5 KPA43924.1 - 0.94 9.6 9.0 0.38 10.9 5.7 2.1 2 0 0 2 2 1 0 Cell-cycle alteration and expression-elevated protein in tumour 5_nucleotid PF05761.14 KPA43924.1 - 0.97 8.3 3.5 1.4 7.8 3.5 1.3 1 0 0 1 1 1 0 5' nucleotidase family YabA PF06156.13 KPA43924.1 - 0.97 10.1 9.7 3.5 8.3 7.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 KPA43924.1 - 1 9.1 8.3 1.7 8.4 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phage_GP20 PF06810.11 KPA43924.1 - 1.2 9.0 13.3 4.2 7.2 4.0 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fmp27_WPPW PF10359.9 KPA43924.1 - 1.2 7.9 7.8 1.8 7.3 7.8 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain GAS PF13851.6 KPA43924.1 - 1.5 8.1 15.7 0.53 9.6 7.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AT_hook PF02178.19 KPA43924.1 - 1.5 8.9 27.0 2.2 8.4 5.4 3.8 3 0 0 3 3 3 0 AT hook motif CENP-O PF09496.10 KPA43924.1 - 1.5 8.7 5.4 2.3 8.1 5.4 1.3 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component XhlA PF10779.9 KPA43924.1 - 1.7 8.9 8.4 0.084 13.1 2.0 2.1 2 1 0 2 2 1 0 Haemolysin XhlA UPF0242 PF06785.11 KPA43924.1 - 1.8 8.7 14.0 4.2 7.4 13.9 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 KPA43924.1 - 1.8 8.6 16.6 0.83 9.7 9.3 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Csm1_N PF18504.1 KPA43924.1 - 1.9 8.9 11.0 0.52 10.7 6.8 2.2 1 1 0 2 2 1 0 Csm1 N-terminal domain TPR_MLP1_2 PF07926.12 KPA43924.1 - 1.9 8.5 23.3 0.48 10.5 19.3 2.0 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein TEX13 PF15186.6 KPA43924.1 - 2.1 8.0 9.4 8.4 6.1 9.3 1.9 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF641 PF04859.12 KPA43924.1 - 2.3 8.5 12.7 3.1 8.1 9.0 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FUSC PF04632.12 KPA43924.1 - 2.5 6.5 9.9 4.6 5.7 9.9 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin_2 PF14523.6 KPA43924.1 - 2.6 8.4 9.6 3.3 8.1 5.5 2.4 1 1 1 2 2 2 0 Syntaxin-like protein Fib_alpha PF08702.10 KPA43924.1 - 3 8.0 7.8 10 6.3 7.8 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 KPA43924.1 - 4.5 7.0 8.3 1.8 8.3 5.5 1.8 2 0 0 2 2 1 0 Hepatic lectin, N-terminal domain Bap31_Bap29_C PF18035.1 KPA43924.1 - 4.6 7.3 14.9 9.4 6.3 6.5 3.6 2 2 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2203 PF09969.9 KPA43924.1 - 4.6 8.0 11.7 0.99 10.1 5.9 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DHR10 PF18595.1 KPA43924.1 - 5.2 7.2 22.2 3 7.9 7.0 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Dzip-like_N PF13815.6 KPA43924.1 - 5.2 7.1 8.3 1.8 8.6 4.6 2.0 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal ADIP PF11559.8 KPA43924.1 - 8.1 6.5 17.7 33 4.6 13.2 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KPA43924.1 - 9.8 6.3 22.5 0.92 9.6 11.3 3.0 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding PigN PF04987.14 KPA43925.1 - 2.1e-161 537.8 39.2 2.7e-161 537.5 39.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KPA43925.1 - 2.5e-09 37.2 4.3 3.4e-08 33.5 4.3 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KPA43925.1 - 1.1e-08 34.9 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KPA43925.1 - 1.6e-05 24.4 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily CYYR1 PF10873.8 KPA43925.1 - 0.19 12.2 1.2 0.45 11.0 1.2 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Fungal_trans PF04082.18 KPA43926.1 - 4.5e-37 127.5 0.0 1.9e-36 125.5 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43926.1 - 7.3e-08 32.4 8.7 1.2e-07 31.7 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Stathmin PF00836.19 KPA43926.1 - 0.034 14.1 1.2 0.071 13.1 1.2 1.4 1 0 0 1 1 1 0 Stathmin family LysM PF01476.20 KPA43927.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 LysM domain Arv1 PF04161.13 KPA43928.1 - 1.4e-78 263.9 0.2 1.7e-78 263.6 0.2 1.0 1 0 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.13 KPA43929.1 - 3e-24 85.3 3.5 3.3e-24 85.1 3.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H OppC_N PF12911.7 KPA43929.1 - 0.029 14.4 1.1 1.7 8.6 0.2 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Popeye PF04831.13 KPA43929.1 - 0.39 10.9 2.4 0.47 10.6 2.4 1.1 1 0 0 1 1 1 0 Popeye protein conserved region NAD_binding_2 PF03446.15 KPA43930.1 - 4.7e-28 98.3 0.2 8.8e-28 97.5 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KPA43930.1 - 1e-09 38.7 0.5 1.9e-09 37.8 0.5 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KPA43930.1 - 4.6e-06 27.1 0.3 3.9e-05 24.2 0.0 2.5 4 0 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KPA43930.1 - 5.9e-06 26.4 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KPA43930.1 - 0.054 13.4 0.1 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding NAT PF04768.13 KPA43931.1 - 2.9e-48 163.7 0.0 7.2e-47 159.2 0.0 2.1 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Potassium_chann PF11404.8 KPA43931.1 - 0.15 11.9 0.7 0.32 10.9 0.7 1.5 1 0 0 1 1 1 0 Potassium voltage-gated channel BAR_2 PF10455.9 KPA43932.1 - 6.1e-58 196.2 0.5 8.8e-58 195.7 0.5 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KPA43932.1 - 3.8e-21 75.8 5.7 1.1e-19 71.0 5.7 2.1 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KPA43932.1 - 0.0015 18.2 1.1 0.01 15.5 0.2 2.1 2 0 0 2 2 2 1 BAR domain of APPL family GCP_C_terminal PF04130.13 KPA43932.1 - 0.019 14.4 0.3 0.18 11.3 0.1 2.0 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal ETC_C1_NDUFA5 PF04716.14 KPA43933.1 - 1.2e-25 89.1 2.3 3e-23 81.4 0.0 2.5 2 0 0 2 2 2 2 ETC complex I subunit conserved region RNA_pol_I_TF PF04090.12 KPA43934.1 - 6e-05 22.6 0.0 0.00027 20.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase I specific initiation factor CN_hydrolase PF00795.22 KPA43935.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Carbon-nitrogen hydrolase DUF805 PF05656.14 KPA43935.1 - 2.3 8.7 5.5 8.2 6.9 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF5592 PF17332.2 KPA43935.1 - 4.4 7.9 8.9 1.2 9.7 5.8 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5592) Asp PF00026.23 KPA43937.1 - 7.8e-07 28.8 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease PTP_tm PF18861.1 KPA43937.1 - 0.05 13.6 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 KPA43937.1 - 0.17 12.8 0.0 0.4 11.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain NACHT PF05729.12 KPA43939.1 - 2e-07 31.1 0.0 6e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPA43939.1 - 0.0012 19.3 0.1 0.023 15.1 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPA43939.1 - 0.0022 18.3 0.0 0.0073 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain YvrJ PF12841.7 KPA43939.1 - 0.018 14.6 0.0 1.7 8.2 0.0 2.9 2 0 0 2 2 2 0 YvrJ protein family DAP3 PF10236.9 KPA43939.1 - 0.03 13.5 0.1 2.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 KPA43939.1 - 0.046 14.3 0.0 7.9 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KPA43939.1 - 0.06 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 KaiC KAP_NTPase PF07693.14 KPA43939.1 - 0.14 11.4 0.0 10 5.2 0.0 2.9 3 0 0 3 3 3 0 KAP family P-loop domain SNF2_N PF00176.23 KPA43940.1 - 7.7e-53 179.4 0.0 4.5e-52 176.9 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KPA43940.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NmrA PF05368.13 KPA43941.1 - 1.8e-17 63.7 0.0 2.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA43941.1 - 1.2e-13 51.3 0.1 2.5e-13 50.3 0.0 1.6 2 1 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPA43941.1 - 2.4e-07 31.0 0.0 4.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPA43941.1 - 3.1e-06 26.9 0.0 4.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 KPA43941.1 - 0.0067 17.2 0.1 0.013 16.3 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KPA43941.1 - 0.0094 16.1 0.2 0.027 14.6 0.1 1.9 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KPA43941.1 - 0.012 16.0 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Big_3_5 PF16640.5 KPA43941.1 - 0.019 15.1 0.8 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Ldh_1_N PF00056.23 KPA43941.1 - 0.024 14.8 0.1 0.058 13.5 0.1 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_33 PF10017.9 KPA43942.1 - 4.6e-25 88.4 0.0 1.8e-21 76.6 0.0 2.0 1 1 1 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent Beta-lactamase PF00144.24 KPA43943.1 - 1.2e-47 162.8 0.1 8e-47 160.1 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase sCache_3_2 PF17203.4 KPA43943.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Single cache domain 3 Zn_clus PF00172.18 KPA43944.1 - 2.6e-06 27.4 5.1 1.1e-05 25.4 5.1 2.1 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1646 PF07854.12 KPA43944.1 - 0.25 10.7 0.0 0.39 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1646) AMP-binding PF00501.28 KPA43945.1 - 1.6e-75 254.4 0.0 2e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA43945.1 - 3.1e-12 47.3 1.5 1.7e-11 44.9 0.8 2.7 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain RPAP1_N PF08621.10 KPA43946.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 RPAP1-like, N-terminal PAP2_3 PF14378.6 KPA43947.1 - 2.6e-36 125.1 14.1 4.2e-27 95.1 3.5 2.4 2 0 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.21 KPA43947.1 - 0.00071 19.3 0.6 0.00071 19.3 0.6 2.7 2 1 1 3 3 3 1 PAP2 superfamily RabGAP-TBC PF00566.18 KPA43948.1 - 3.5e-37 128.2 3.1 8.1e-37 127.0 3.1 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KPA43948.1 - 1.4e-06 27.9 0.0 3.5e-05 23.3 0.0 2.8 2 1 0 2 2 2 1 Rab-binding domain (RBD) Mso1_Sec1_bdg PF14475.6 KPA43949.1 - 4.3e-21 74.2 0.1 6.8e-21 73.6 0.1 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 KPA43950.1 - 2.7e-34 118.4 0.1 5.6e-34 117.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KPA43950.1 - 5.1e-27 94.4 12.9 5.1e-27 94.4 12.9 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KPA43950.1 - 8.9e-06 25.3 14.2 1.1e-05 25.0 14.2 1.1 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 KPA43950.1 - 0.039 12.5 23.2 0.048 12.3 23.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PYC_OADA PF02436.18 KPA43950.1 - 0.06 13.1 0.3 0.1 12.4 0.3 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain Reovirus_cap PF00979.17 KPA43950.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 DUF2462 PF09495.10 KPA43950.1 - 0.13 13.0 5.5 5.9 7.7 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) Drc1-Sld2 PF11719.8 KPA43950.1 - 2.8 7.4 19.3 5.7 6.4 19.2 1.6 1 1 0 1 1 1 0 DNA replication and checkpoint protein YL1 PF05764.13 KPA43950.1 - 8.4 6.4 31.9 0.49 10.5 23.5 2.1 2 0 0 2 2 2 0 YL1 nuclear protein Vps55 PF04133.14 KPA43951.1 - 9.1e-45 151.4 8.9 1e-44 151.2 8.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 ABC2_membrane_3 PF12698.7 KPA43951.1 - 2.9 6.9 11.1 3.4 6.7 11.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Chorismate_bind PF00425.18 KPA43952.1 - 3e-66 223.6 0.0 4e-65 219.9 0.0 2.0 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KPA43952.1 - 8.5e-25 87.6 0.0 1.9e-24 86.5 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KPA43952.1 - 9.6e-12 45.3 0.0 3.5e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KPA43952.1 - 9.6e-06 25.5 0.1 3.2e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 UPF0061 PF02696.14 KPA43953.1 - 6.8e-130 434.0 0.0 8.7e-130 433.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Molybdopterin PF00384.22 KPA43954.1 - 2e-72 244.5 0.0 1.7e-70 238.2 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KPA43954.1 - 7.5e-20 70.8 0.1 2.2e-19 69.3 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KPA43954.1 - 1.9e-19 70.1 0.0 4.7e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KPA43954.1 - 1.8e-17 62.6 0.2 1.8e-17 62.6 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KPA43954.1 - 6.6e-08 32.4 0.5 6.6e-08 32.4 0.5 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KPA43954.1 - 0.0022 17.8 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain ACBP PF00887.19 KPA43956.1 - 2.4e-23 82.2 0.5 2.1e-22 79.1 0.0 2.3 2 0 0 2 2 2 1 Acyl CoA binding protein Ribonuclease_3 PF00636.26 KPA43957.1 - 3.4e-15 56.6 0.0 7.3e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KPA43957.1 - 5.7e-08 33.0 0.0 1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like MRP-S33 PF08293.11 KPA43958.1 - 3.1e-31 107.5 0.1 3.6e-31 107.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.19 KPA43959.1 - 1.3e-39 131.6 0.7 3.7e-06 26.3 0.0 9.2 10 0 0 10 10 10 8 Pumilio-family RNA binding repeat DUF4945 PF16303.5 KPA43959.1 - 0.062 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) ATP-synt_D PF01813.17 KPA43959.1 - 0.094 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 ATP synthase subunit D Phage_lambda_P PF06992.11 KPA43959.1 - 0.19 11.5 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 Replication protein P DUF5572 PF17733.1 KPA43960.1 - 7.1e-19 67.4 1.0 1.3e-18 66.5 1.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) PP2C PF00481.21 KPA43961.1 - 5.4e-41 140.9 0.0 8.6e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KPA43961.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C SpoIIE PF07228.12 KPA43961.1 - 0.051 13.5 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) SLAC1 PF03595.17 KPA43962.1 - 5.2e-73 246.1 50.2 7e-73 245.7 50.2 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel RseC_MucC PF04246.12 KPA43962.1 - 0.1 12.5 1.7 0.55 10.2 0.4 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Rhomboid PF01694.22 KPA43963.1 - 1.2e-06 28.5 1.9 1.2e-06 28.5 1.9 1.5 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 KPA43963.1 - 4.5e-06 27.2 0.4 7.9e-06 26.4 0.4 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Gly-zipper_Omp PF13488.6 KPA43963.1 - 0.83 9.7 3.7 0.63 10.1 0.4 2.3 2 0 0 2 2 2 0 Glycine zipper Uds1 PF15456.6 KPA43964.1 - 1.3e-42 145.0 8.2 1.3e-42 145.0 8.2 10.0 3 2 7 10 10 10 2 Up-regulated During Septation HR1 PF02185.16 KPA43964.1 - 0.00011 22.2 2.4 0.00011 22.2 2.4 14.1 11 2 4 15 15 15 5 Hr1 repeat ABC_tran_CTD PF16326.5 KPA43964.1 - 0.00063 19.9 1.1 0.00063 19.9 1.1 15.0 7 3 8 15 15 15 6 ABC transporter C-terminal domain TMF_DNA_bd PF12329.8 KPA43964.1 - 0.0013 18.7 5.9 0.0013 18.7 5.9 13.2 10 4 3 14 14 14 3 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KPA43964.1 - 0.0023 18.2 19.5 0.0023 18.2 19.5 9.7 4 2 6 10 10 10 3 Autophagy protein 16 (ATG16) Tropomyosin PF00261.20 KPA43964.1 - 0.0029 17.0 42.1 0.0029 17.0 42.1 10.2 6 1 1 8 8 8 3 Tropomyosin FliJ PF02050.16 KPA43964.1 - 0.0035 17.6 6.2 0.0035 17.6 6.2 10.3 6 1 6 12 12 12 2 Flagellar FliJ protein Baculo_PEP_C PF04513.12 KPA43964.1 - 0.13 12.3 57.8 0.046 13.8 1.8 9.0 4 2 5 9 9 9 0 Baculovirus polyhedron envelope protein, PEP, C terminus FPP PF05911.11 KPA43964.1 - 4.4 5.4 104.4 0.068 11.4 15.1 6.4 3 1 2 5 5 5 0 Filament-like plant protein, long coiled-coil Tcp11 PF05794.13 KPA43965.1 - 5e-106 355.5 0.0 7.2e-106 354.9 0.0 1.2 1 0 0 1 1 1 1 T-complex protein 11 Peptidase_M75 PF09375.10 KPA43965.1 - 0.032 13.7 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Imelysin DUF1242 PF06842.12 KPA43966.1 - 2e-18 65.9 0.3 3.2e-18 65.2 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.16 KPA43967.1 - 2.4e-18 65.9 0.0 3.5e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KPA43967.1 - 0.00027 20.9 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 KPA43967.1 - 0.0021 18.4 0.3 0.0078 16.6 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KPA43967.1 - 0.037 14.3 0.2 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KPA43967.1 - 0.1 12.7 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 KPA43967.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit EamA PF00892.20 KPA43968.1 - 6e-18 65.3 22.2 4e-09 36.8 3.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family DMT_YdcZ PF04657.13 KPA43968.1 - 0.0018 18.6 3.3 0.0018 18.6 3.3 2.6 2 1 0 2 2 2 1 Putative inner membrane exporter, YdcZ Trp_oprn_chp PF09534.10 KPA43968.1 - 0.045 13.5 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Fungal_trans PF04082.18 KPA43969.1 - 8.6e-12 44.6 0.5 8.6e-12 44.6 0.5 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA43969.1 - 6.6e-08 32.6 14.1 1.2e-07 31.7 14.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.23 KPA43970.1 - 1.6e-82 277.3 29.0 1e-43 149.9 13.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA43970.1 - 2.3e-71 238.7 0.0 2.2e-34 118.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPA43970.1 - 5e-15 55.5 1.4 1.1e-05 25.0 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KPA43970.1 - 2.4e-08 34.3 0.2 0.005 17.1 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KPA43970.1 - 2.9e-08 33.3 0.2 0.0027 17.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KPA43970.1 - 1.6e-07 30.5 4.0 0.0038 16.1 0.1 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KPA43970.1 - 2.2e-07 31.4 0.9 0.004 17.5 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KPA43970.1 - 5.2e-07 29.7 0.1 0.044 13.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 KPA43970.1 - 1.1e-06 28.0 0.2 0.11 11.7 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin AAA_15 PF13175.6 KPA43970.1 - 1.6e-06 28.1 0.0 0.058 13.1 0.0 2.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KPA43970.1 - 2.1e-05 24.2 0.4 0.22 11.1 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KPA43970.1 - 3.6e-05 23.6 0.3 1.4 8.6 0.0 4.0 4 0 0 4 4 4 2 AAA domain G-alpha PF00503.20 KPA43970.1 - 0.00017 20.9 0.0 0.53 9.4 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 KPA43970.1 - 0.0004 20.3 1.8 5.4 6.7 0.2 4.2 2 2 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KPA43970.1 - 0.00049 20.7 0.2 0.39 11.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 KPA43970.1 - 0.00092 19.4 1.8 2.9 8.2 0.1 4.5 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KPA43970.1 - 0.0012 18.8 0.1 3.7 7.5 0.0 3.2 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 KPA43970.1 - 0.007 16.8 0.9 23 5.4 0.0 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 KPA43970.1 - 0.01 15.8 0.1 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 KPA43970.1 - 0.011 15.9 2.6 0.83 9.7 0.1 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_33 PF13671.6 KPA43970.1 - 0.011 15.9 0.0 3.5 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPA43970.1 - 0.012 15.4 0.1 6.2 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KPA43970.1 - 0.015 14.8 0.0 4.4 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KPA43970.1 - 0.015 14.4 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) APS_kinase PF01583.20 KPA43970.1 - 0.025 14.5 0.4 4.4 7.2 0.0 3.4 2 1 1 3 3 3 0 Adenylylsulphate kinase NB-ARC PF00931.22 KPA43970.1 - 0.031 13.5 0.0 3.7 6.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 KPA43970.1 - 0.032 14.3 0.1 5.6 7.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATPase PF06745.13 KPA43970.1 - 0.037 13.4 1.0 0.53 9.6 0.2 2.5 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 KPA43970.1 - 0.055 13.5 0.0 23 5.0 0.0 3.6 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.15 KPA43970.1 - 0.061 13.2 0.0 0.6 10.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 KPA43970.1 - 0.075 13.3 0.0 0.78 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KPA43970.1 - 0.076 13.6 0.1 16 6.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KPA43970.1 - 0.088 13.2 0.1 6.5 7.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KPA43970.1 - 0.14 12.1 0.7 19 5.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain PRK PF00485.18 KPA43970.1 - 0.15 11.7 3.4 6.8 6.4 0.0 3.4 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family DUF5383 PF17355.2 KPA43970.1 - 0.2 12.0 3.8 0.46 10.9 0.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Halogen_Hydrol PF10112.9 KPA43970.1 - 0.45 10.5 3.0 3 7.8 1.5 2.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Sec16_C PF12931.7 KPA43971.1 - 3.1e-112 375.1 0.0 4.4e-112 374.6 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KPA43971.1 - 1e-34 119.7 0.0 5.5e-34 117.3 0.0 2.4 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.7 KPA43971.1 - 2.4e-11 44.3 43.8 2.4e-11 44.3 43.8 4.8 3 1 1 5 5 5 1 Vesicle coat trafficking protein Sec16 N-terminus Hus1 PF04005.12 KPA43972.1 - 2.8e-88 295.8 0.0 3.1e-88 295.7 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein FH2 PF02181.23 KPA43974.1 - 1.8e-84 284.0 5.3 1.8e-84 284.0 5.3 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KPA43974.1 - 2e-62 210.1 0.0 6.4e-62 208.5 0.0 2.0 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KPA43974.1 - 1.4e-52 178.1 2.7 6.5e-52 176.0 2.1 2.4 1 1 1 2 2 2 1 Diaphanous FH3 Domain SNRNP27 PF08648.12 KPA43975.1 - 3e-29 100.8 2.8 7.7e-29 99.5 2.8 1.7 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Glyco_hydro_63 PF03200.16 KPA43976.1 - 3.2e-173 577.0 0.9 3.9e-172 573.4 0.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KPA43976.1 - 1.1e-79 267.7 0.6 3.9e-79 265.9 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KPA43976.1 - 2.7e-08 33.1 0.1 5.1e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Trehalase Collagen PF01391.18 KPA43977.1 - 0.013 15.2 8.2 0.022 14.5 8.2 1.5 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) TrmE_N PF10396.9 KPA43978.1 - 1.8e-35 121.7 0.0 4.6e-35 120.4 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KPA43978.1 - 1.7e-33 116.5 2.7 2.2e-33 116.2 2.7 1.1 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KPA43978.1 - 1e-19 70.7 0.0 2.5e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPA43978.1 - 7.1e-06 25.6 0.0 1.3e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KPA43978.1 - 0.0004 20.3 0.1 0.0081 16.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KPA43978.1 - 0.00054 20.1 0.0 0.0014 18.7 0.0 1.8 1 1 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 KPA43978.1 - 0.0035 16.9 0.2 0.084 12.4 0.2 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KPA43978.1 - 0.022 15.2 0.3 0.048 14.2 0.1 1.8 1 1 1 2 2 2 0 ABC transporter AAA_24 PF13479.6 KPA43978.1 - 0.029 14.1 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_hydro_3_C PF01915.22 KPA43978.1 - 0.079 12.9 0.0 0.2 11.6 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain NatB_MDM20 PF09797.9 KPA43978.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit CorA PF01544.18 KPA43978.1 - 0.3 10.4 1.9 0.47 9.7 1.9 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Aminotran_5 PF00266.19 KPA43979.1 - 6.6e-33 114.2 0.0 1.6e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Proteasome PF00227.26 KPA43980.1 - 6.8e-49 165.9 0.1 8.5e-49 165.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KPA43980.1 - 4.8e-11 42.1 0.2 7.8e-11 41.4 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lysine_decarbox PF03641.14 KPA43981.1 - 1.7e-28 99.3 0.1 2.4e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KPA43981.1 - 5.1e-06 26.2 3.1 9.3e-06 25.3 1.3 2.1 2 1 0 2 2 2 1 SLOG cluster4 family CLPTM1 PF05602.12 KPA43982.1 - 6.3e-150 499.9 0.0 7.7e-150 499.6 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF938 PF06080.12 KPA43982.1 - 0.0032 17.3 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) CD47 PF04549.14 KPA43982.1 - 2.2 8.5 8.2 0.21 11.8 1.8 2.0 2 0 0 2 2 2 0 CD47 transmembrane region PyrI_C PF02748.15 KPA43983.1 - 0.053 13.4 0.1 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.12 KPA43983.1 - 0.33 11.3 2.8 1.2 9.5 0.7 2.8 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF4734 PF15881.5 KPA43983.1 - 0.39 10.9 2.5 9.7 6.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) Longin PF13774.6 KPA43984.1 - 2.6e-24 85.1 0.2 4.6e-24 84.3 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KPA43984.1 - 1.9e-15 56.4 0.1 2.9e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 Synaptobrevin DUF5435 PF17503.2 KPA43984.1 - 0.0053 16.5 0.2 0.01 15.6 0.1 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5435) Paf67 PF10255.9 KPA43984.1 - 0.019 14.0 0.0 0.04 12.9 0.0 1.5 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 DUF1664 PF07889.12 KPA43984.1 - 0.039 14.0 1.6 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_tail_APC PF16778.5 KPA43984.1 - 0.12 12.3 0.0 4.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Phage tail assembly chaperone protein SLM4 PF16818.5 KPA43984.1 - 0.17 11.8 0.9 1.8 8.5 0.1 2.2 1 1 1 2 2 2 0 Protein SLM4 Elong_Iki1 PF10483.9 KPA43985.1 - 3.9e-103 345.1 0.0 4.5e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 NACHT PF05729.12 KPA43985.1 - 0.15 12.0 0.2 0.56 10.1 0.3 2.0 2 1 0 2 2 2 0 NACHT domain Bystin PF05291.11 KPA43987.1 - 5.2e-129 429.7 0.0 6.6e-129 429.4 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.14 KPA43988.1 - 1.5e-64 217.2 0.9 3.8e-64 215.9 0.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KPA43988.1 - 4.1e-21 74.6 1.6 9.8e-21 73.4 1.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Terminase_2 PF03592.16 KPA43988.1 - 0.16 12.4 0.7 0.31 11.5 0.7 1.5 1 0 0 1 1 1 0 Terminase small subunit Kelch_5 PF13854.6 KPA43989.1 - 4.9e-14 51.9 2.2 4e-11 42.6 0.3 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 KPA43989.1 - 4.7e-06 26.7 4.0 0.013 15.7 0.0 5.4 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KPA43989.1 - 0.0097 15.5 1.2 5.2 6.7 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 KPA43989.1 - 0.019 15.3 0.7 2 8.8 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 KPA43989.1 - 0.68 10.0 7.3 2.7 8.1 0.2 4.5 4 1 0 4 4 4 0 Galactose oxidase, central domain DUF3060 PF11259.8 KPA43991.1 - 0.0026 17.4 1.1 0.0026 17.4 1.1 3.9 3 1 0 3 3 3 1 Protein of unknown function (DUF3060) BIR PF00653.21 KPA43992.1 - 1.1e-46 157.3 4.2 1.8e-22 79.8 1.7 3.3 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain AT_hook PF02178.19 KPA43992.1 - 2.6e-06 26.7 19.4 0.12 12.3 1.5 4.6 3 0 0 3 3 3 3 AT hook motif CoA_binding_2 PF13380.6 KPA43993.1 - 1e-26 93.7 0.0 1.1e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain EF-hand_7 PF13499.6 KPA43994.1 - 6.4e-14 52.2 0.2 5.2e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KPA43994.1 - 1.4e-13 51.0 0.1 4.7e-07 30.0 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KPA43994.1 - 3.1e-11 42.3 0.5 0.00014 21.5 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KPA43994.1 - 1.9e-10 39.5 0.5 0.00083 18.7 0.0 3.7 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KPA43994.1 - 1.3e-07 31.3 0.1 6.8e-05 22.6 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain pair PhetRS_B1 PF18262.1 KPA43994.1 - 0.014 15.6 0.1 6.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain EF-hand_14 PF17959.1 KPA43994.1 - 0.15 12.4 0.0 17 5.8 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain GPHH PF16905.5 KPA43994.1 - 0.22 11.3 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Peptidase_M3 PF01432.20 KPA43995.1 - 1.6e-145 485.9 0.0 2e-145 485.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 KPA43995.1 - 0.042 14.2 0.0 0.19 12.0 0.1 2.0 2 0 0 2 2 2 0 Effector protein DUF1409 PF07197.12 KPA43995.1 - 0.07 13.0 0.0 6.6 6.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) MFS_1 PF07690.16 KPA43996.1 - 2.8e-31 108.7 28.2 2.8e-31 108.7 28.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2208 PF09973.9 KPA43996.1 - 0.013 15.1 0.7 0.72 9.4 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Git3 PF11710.8 KPA43997.1 - 0.28 10.9 12.8 0.5 10.1 12.8 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 F-box-like PF12937.7 KPA43998.1 - 5.2e-06 26.2 1.6 1.5e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KPA43998.1 - 0.0052 16.6 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain CDH-cyt PF16010.5 KPA44000.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome domain of cellobiose dehydrogenase Glyco_transf_22 PF03901.17 KPA44001.1 - 4.2e-83 279.9 20.8 4.9e-83 279.7 20.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.14 KPA44002.1 - 5.6e-48 162.6 0.4 5.6e-48 162.6 0.4 1.7 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region YL1 PF05764.13 KPA44002.1 - 0.34 11.0 10.4 1 9.4 1.5 2.1 2 0 0 2 2 2 0 YL1 nuclear protein API5 PF05918.11 KPA44002.1 - 2.1 7.0 3.4 3 6.5 3.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Peptidase_M28 PF04389.17 KPA44003.1 - 2e-29 102.7 0.0 3.4e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KPA44003.1 - 4.7e-06 26.4 0.3 1.4e-05 24.9 0.1 1.9 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 Nucleoporin2 PF04096.14 KPA44003.1 - 0.051 13.7 0.4 0.091 12.9 0.4 1.3 1 0 0 1 1 1 0 Nucleoporin autopeptidase CNDH2_C PF16858.5 KPA44004.1 - 0.14 12.0 3.2 0.21 11.4 3.2 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF1176 PF06674.11 KPA44004.1 - 0.29 10.5 3.8 0.46 9.9 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Sld5 PF05916.11 KPA44005.1 - 2.1e-33 115.0 0.0 5.3e-33 113.7 0.0 1.7 1 1 0 1 1 1 1 GINS complex protein Acetyltransf_9 PF13527.7 KPA44006.1 - 6.1e-05 23.1 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA44006.1 - 0.00056 20.3 0.0 0.001 19.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA44006.1 - 0.00099 19.3 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA44006.1 - 0.0087 16.0 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA44006.1 - 0.045 13.7 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein MOZ_SAS PF01853.18 KPA44006.1 - 0.21 11.2 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family ProRS-C_1 PF09180.11 KPA44007.1 - 1e-23 83.3 1.1 1.6e-23 82.7 0.2 1.8 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KPA44007.1 - 1.1e-20 74.3 0.0 2.2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KPA44007.1 - 2.6e-19 69.1 0.1 6.5e-19 67.9 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain MT0933_antitox PF14013.6 KPA44007.1 - 7.6 6.9 10.9 1.4 9.3 4.8 2.6 2 0 0 2 2 2 0 MT0933-like antitoxin protein Cpn60_TCP1 PF00118.24 KPA44008.1 - 3.3e-152 507.6 12.4 3.7e-152 507.4 12.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MMS1_N PF10433.9 KPA44009.1 - 2e-121 406.1 0.0 2.8e-121 405.5 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KPA44009.1 - 3.7e-54 184.2 0.0 8.4e-54 183.0 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region Rieske PF00355.26 KPA44009.1 - 2.4e-10 40.2 0.0 6.3e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KPA44009.1 - 5.3e-08 33.2 0.2 1.3e-07 32.0 0.2 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region R3H-assoc PF13902.6 KPA44011.1 - 5.5e-23 81.8 3.0 5.5e-23 81.8 3.0 1.7 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 KPA44011.1 - 0.0021 18.0 0.0 0.0089 16.0 0.0 2.1 2 0 0 2 2 2 1 R3H domain AflR PF08493.10 KPA44011.1 - 3.6 7.0 8.6 6.5 6.1 8.6 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein PQ-loop PF04193.14 KPA44012.1 - 5.1e-21 74.2 15.9 2.3e-12 46.5 1.0 3.6 3 1 1 4 4 4 2 PQ loop repeat HC2 PF07382.11 KPA44013.1 - 0.087 12.9 68.1 22 5.1 68.0 2.4 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Fmp27 PF10344.9 KPA44015.1 - 2.7e-210 700.8 0.0 5.4e-210 699.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KPA44015.1 - 2.7e-198 659.7 0.6 2.7e-198 659.7 0.6 3.1 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KPA44015.1 - 1.1e-176 588.5 1.6 2.4e-176 587.4 0.1 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KPA44015.1 - 1.3e-55 187.5 0.2 3.2e-55 186.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 KPA44015.1 - 8.5e-54 181.9 0.0 1.9e-53 180.7 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 KPA44015.1 - 7.9e-34 116.5 0.1 4.6e-33 114.0 0.1 2.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain GPS2_interact PF15784.5 KPA44016.1 - 0.014 15.8 1.1 0.023 15.1 1.1 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain PT-VENN PF04829.13 KPA44016.1 - 0.034 14.2 0.1 0.034 14.2 0.1 2.3 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Bacteriocin_IIc PF10439.9 KPA44016.1 - 2.5 8.3 12.3 0.44 10.7 1.9 2.6 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide RRM_1 PF00076.22 KPA44017.1 - 3.2e-13 49.3 0.0 6.1e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hamartin PF04388.12 KPA44017.1 - 1.6 7.3 9.2 2 7.0 9.2 1.1 1 0 0 1 1 1 0 Hamartin protein NUDIX PF00293.28 KPA44018.1 - 1.2e-06 28.6 0.7 3e-06 27.3 0.7 1.5 1 1 0 1 1 1 1 NUDIX domain ABA_GPCR PF12430.8 KPA44019.1 - 1.1e-55 188.2 1.0 2.3e-55 187.1 1.0 1.6 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KPA44019.1 - 3.7e-24 84.6 0.1 7e-23 80.5 0.0 2.4 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal Usp PF00582.26 KPA44020.1 - 2.3e-13 50.8 2.0 3.7e-13 50.2 0.0 2.3 2 1 0 2 2 2 1 Universal stress protein family Paf67 PF10255.9 KPA44021.1 - 4.1e-156 520.0 0.1 4.8e-156 519.8 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KPA44021.1 - 0.0082 16.2 0.2 0.078 13.1 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KPA44021.1 - 0.14 12.0 0.2 0.99 9.3 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 KPA44022.1 - 2.1e-58 197.0 0.0 3.8e-58 196.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KPA44022.1 - 5.8e-16 58.3 0.0 1.4e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KPA44022.1 - 1e-10 41.8 0.0 4.3e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KPA44022.1 - 3e-07 30.4 0.0 1e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.18 KPA44022.1 - 0.0015 18.3 0.0 0.017 14.9 0.0 2.7 2 1 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KPA44022.1 - 0.015 15.3 0.0 0.041 14.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase DOT1 PF08123.13 KPA44025.1 - 5.4e-73 244.9 0.1 1.1e-72 243.9 0.1 1.5 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 KPA44025.1 - 0.0062 17.2 0.0 0.015 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA44025.1 - 0.025 14.4 0.0 0.097 12.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 KPA44025.1 - 0.15 11.3 0.1 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ATG16 PF08614.11 KPA44026.1 - 1.1e-53 182.5 19.5 1.3e-53 182.3 19.5 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4250 PF14056.6 KPA44026.1 - 0.0056 16.6 2.0 0.17 11.8 0.6 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4250) DUF5031 PF16434.5 KPA44026.1 - 0.079 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5031) Golgin_A5 PF09787.9 KPA44026.1 - 0.083 12.4 17.7 0.13 11.7 17.7 1.2 1 1 0 1 1 1 0 Golgin subfamily A member 5 Tnp_22_trimer PF17489.2 KPA44026.1 - 0.24 11.4 0.0 0.24 11.4 0.0 4.0 3 1 1 4 4 4 0 L1 transposable element trimerization domain APG6_N PF17675.1 KPA44026.1 - 0.26 11.8 18.8 2 8.9 18.6 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 KPA44026.1 - 0.34 10.0 9.4 0.38 9.8 9.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS-augmin3 PF14932.6 KPA44026.1 - 0.4 10.2 10.1 0.35 10.4 7.8 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Noggin PF05806.12 KPA44026.1 - 0.49 10.3 3.8 0.66 9.9 3.8 1.2 1 0 0 1 1 1 0 Noggin UPF0242 PF06785.11 KPA44026.1 - 1.3 9.1 17.4 6.1 6.9 5.0 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Med26 PF08711.11 KPA44026.1 - 2.4 8.3 7.0 83 3.3 7.0 2.8 1 1 0 1 1 1 0 TFIIS helical bundle-like domain PspB PF06667.12 KPA44026.1 - 2.5 8.2 0.0 2.5 8.2 0.0 3.2 2 1 1 3 3 3 0 Phage shock protein B DUF1664 PF07889.12 KPA44026.1 - 3.9 7.5 7.4 2.7 8.1 5.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 KPA44026.1 - 6.4 7.0 15.3 4.5 7.5 12.6 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein Vps16_N PF04841.13 KPA44027.1 - 1.5e-86 290.7 0.0 2.1e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KPA44027.1 - 1.3e-82 277.5 0.0 1.8e-82 276.9 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KPA44027.1 - 0.0065 16.7 0.0 0.054 13.8 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain FHA PF00498.26 KPA44028.1 - 7.8e-14 51.8 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KPA44028.1 - 6.7e-13 48.1 6.4 1.2e-12 47.4 6.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KPA44028.1 - 7.2e-07 29.4 9.7 1.2e-06 28.8 9.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KPA44028.1 - 0.0019 18.0 9.1 0.0033 17.3 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 KPA44028.1 - 0.0044 17.3 0.0 0.009 16.3 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PHD PF00628.29 KPA44028.1 - 0.0072 16.2 4.1 0.013 15.4 4.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-rbx1 PF12678.7 KPA44028.1 - 0.037 14.3 5.8 0.087 13.1 5.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KPA44028.1 - 0.041 13.8 6.5 0.067 13.2 6.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KPA44028.1 - 0.061 13.2 8.7 0.11 12.4 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA44028.1 - 0.17 11.9 8.9 0.35 10.9 8.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KPA44028.1 - 0.2 11.7 1.4 0.36 10.9 1.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger lci PF12197.8 KPA44028.1 - 0.25 11.2 0.8 0.64 9.9 0.8 1.7 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein Zn_ribbon_17 PF17120.5 KPA44028.1 - 0.86 9.3 3.4 1.8 8.2 3.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KPA44028.1 - 3.7 7.8 6.8 8.5 6.6 6.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Peptidase_M16_C PF05193.21 KPA44029.1 - 4.2e-52 176.8 0.0 8.9e-52 175.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KPA44029.1 - 1.4e-42 145.2 0.0 2.6e-40 137.8 0.0 2.3 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) S1 PF00575.23 KPA44031.1 - 9.8e-78 256.5 40.9 9.6e-14 51.5 0.5 12.7 12 0 0 12 12 12 10 S1 RNA binding domain RNase_II_C_S1 PF18614.1 KPA44031.1 - 2.4e-06 27.4 0.6 0.34 10.9 0.1 5.4 5 0 0 5 5 5 1 RNase II-type exonuclease C-terminal S1 domain S1_2 PF13509.6 KPA44031.1 - 5.9e-05 23.0 0.1 15 5.7 0.0 5.7 5 0 0 5 5 5 1 S1 domain TPR_19 PF14559.6 KPA44031.1 - 0.00015 22.2 1.1 0.22 12.1 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KPA44031.1 - 0.00069 20.2 10.3 0.2 12.6 0.0 5.5 3 1 3 6 6 6 2 Tetratricopeptide repeat SDA1 PF05285.12 KPA44031.1 - 0.0011 18.4 23.5 0.0011 18.4 23.5 3.0 2 1 0 2 2 2 1 SDA1 NRDE-2 PF08424.10 KPA44031.1 - 0.0021 17.3 1.4 0.0054 15.9 0.5 2.1 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference Suf PF05843.14 KPA44031.1 - 0.16 11.9 0.0 0.16 11.9 0.0 3.8 2 1 2 4 4 4 0 Suppressor of forked protein (Suf) EF-hand_4 PF12763.7 KPA44033.1 - 2.4e-05 24.2 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Mucin15 PF15672.5 KPA44034.1 - 0.0043 16.6 0.3 0.0066 16.0 0.3 1.2 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 EphA2_TM PF14575.6 KPA44034.1 - 0.0076 17.1 0.0 0.019 15.8 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 KPA44034.1 - 0.013 16.1 0.6 0.013 16.1 0.6 1.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.10 KPA44034.1 - 0.038 13.4 0.7 0.072 12.5 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.6 KPA44034.1 - 0.049 13.4 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SesA PF17107.5 KPA44035.1 - 4e-05 23.8 2.3 0.00012 22.3 2.3 1.9 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF2408 PF10303.9 KPA44035.1 - 0.0016 19.0 3.7 0.0045 17.6 3.6 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2408) Laminin_II PF06009.12 KPA44035.1 - 0.0018 18.3 2.2 0.0044 17.1 2.2 1.7 1 0 0 1 1 1 1 Laminin Domain II FlxA PF14282.6 KPA44035.1 - 0.019 15.0 1.8 0.032 14.2 1.8 1.4 1 0 0 1 1 1 0 FlxA-like protein DUF1870 PF08965.10 KPA44035.1 - 0.043 13.8 0.1 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) V_ATPase_I PF01496.19 KPA44035.1 - 0.094 10.6 0.7 0.13 10.1 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ran-binding PF05508.11 KPA44035.1 - 0.13 11.2 3.8 0.18 10.8 3.8 1.2 1 0 0 1 1 1 0 RanGTP-binding protein NPV_P10 PF05531.12 KPA44035.1 - 0.22 12.0 5.3 1.3 9.5 2.2 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KPA44035.1 - 1.8 8.6 5.0 1.6 8.7 1.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KPA44035.1 - 5.2 7.4 7.3 0.58 10.4 1.0 2.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) tRNA-synt_1c PF00749.21 KPA44036.1 - 4.1e-93 311.7 0.9 5.4e-93 311.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KPA44036.1 - 1.1e-32 113.3 0.0 3e-32 111.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Fungal_trans PF04082.18 KPA44037.1 - 9.9e-17 60.8 0.0 1.8e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA44037.1 - 4.9e-10 39.4 28.3 5.7e-07 29.5 14.9 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain MAP65_ASE1 PF03999.12 KPA44038.1 - 1.3e-78 265.3 9.2 1.3e-75 255.3 0.1 1.9 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) DUF4407 PF14362.6 KPA44038.1 - 0.72 9.2 11.2 0.22 10.9 1.7 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) peroxidase PF00141.23 KPA44040.1 - 8.7e-29 100.8 0.0 1.3e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KPA44040.1 - 0.017 15.1 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Fungal peroxidase extension region His_Phos_1 PF00300.22 KPA44041.1 - 3e-09 36.9 0.2 1e-08 35.1 0.2 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) EphA2_TM PF14575.6 KPA44042.1 - 0.045 14.6 0.0 0.11 13.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Nha1_C PF08619.10 KPA44042.1 - 0.1 11.8 0.8 0.16 11.2 0.7 1.4 1 1 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus TraL PF07178.11 KPA44042.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 TraL protein DUF4246 PF14033.6 KPA44043.1 - 6.4e-176 585.9 0.0 7.4e-176 585.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KPA44043.1 - 0.064 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PEX11 PF05648.14 KPA44044.1 - 0.002 17.6 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Hemerythrin PF01814.23 KPA44045.1 - 1.7e-11 44.9 0.4 2.2e-11 44.5 0.4 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain eIF-3c_N PF05470.12 KPA44046.1 - 1.8e-175 584.7 19.7 1.8e-175 584.7 19.7 3.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KPA44046.1 - 2.1e-14 53.9 0.1 1.3e-13 51.3 0.0 2.5 2 1 0 2 2 2 1 PCI domain DUF2779 PF11074.8 KPA44046.1 - 0.057 13.9 0.4 2.1 8.8 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) Nop14 PF04147.12 KPA44046.1 - 0.15 10.3 18.4 0.25 9.5 18.4 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KPA44046.1 - 0.86 7.8 18.2 1.4 7.1 18.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Fe-S_biosyn PF01521.20 KPA44047.1 - 7.4e-14 51.9 0.0 2.2e-12 47.2 0.0 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Par3_HAL_N_term PF12053.8 KPA44047.1 - 0.06 13.6 0.1 3.3 8.0 0.0 2.8 3 0 0 3 3 3 0 N-terminal of Par3 and HAL proteins Ribosomal_L30_N PF08079.12 KPA44048.1 - 1.1e-25 89.6 17.7 1.9e-25 88.9 17.7 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KPA44048.1 - 5.7e-18 64.5 3.0 5.7e-18 64.5 3.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Tipalpha PF16753.5 KPA44048.1 - 0.03 14.2 0.9 0.061 13.1 0.0 1.9 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter Ribosomal_S11 PF00411.19 KPA44049.1 - 2.2e-46 156.8 1.6 2.8e-46 156.4 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Pilus_CpaD PF09476.10 KPA44049.1 - 0.075 12.8 0.1 0.095 12.4 0.1 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) CBM_25 PF03423.13 KPA44049.1 - 0.077 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) SNF2_N PF00176.23 KPA44050.1 - 1e-66 225.1 0.0 2.1e-66 224.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA44050.1 - 6.7e-16 58.6 0.0 1.6e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA44050.1 - 2.2e-08 34.3 0.1 8.5e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KPA44050.1 - 0.00041 19.6 0.3 0.0021 17.3 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF2935 PF11155.8 KPA44050.1 - 0.16 12.3 1.9 0.56 10.5 1.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) ABC_tran_CTD PF16326.5 KPA44050.1 - 0.99 9.7 8.2 2.7 8.3 0.4 3.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain TMCO5 PF14992.6 KPA44050.1 - 1.4 8.4 11.3 3.1 7.3 11.3 1.5 1 0 0 1 1 1 0 TMCO5 family DUF1664 PF07889.12 KPA44050.1 - 2.1 8.4 5.0 5.2 7.1 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.11 KPA44050.1 - 2.7 7.5 5.6 5.2 6.5 5.6 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein ApbA_C PF08546.11 KPA44051.1 - 1.6e-28 99.4 0.0 2.6e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KPA44051.1 - 2.6e-22 79.1 0.0 4.9e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KPA44051.1 - 0.14 12.4 0.0 6.1 7.1 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Myb_DNA-bind_6 PF13921.6 KPA44052.1 - 2.3e-14 53.4 0.1 1.1e-07 32.0 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KPA44052.1 - 6.1e-13 48.7 0.2 3.1e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 KPA44052.1 - 0.093 12.6 0.0 4.5 7.2 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain AtuA PF07287.11 KPA44052.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA Sigma70_r4_2 PF08281.12 KPA44052.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 PROCN PF08083.11 KPA44053.1 - 1.2e-233 775.1 9.3 1.2e-233 775.1 9.3 1.7 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KPA44053.1 - 1.3e-126 420.9 1.2 2.4e-126 420.0 1.2 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KPA44053.1 - 2.6e-89 297.2 3.3 1.2e-88 295.1 2.0 2.6 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KPA44053.1 - 8.4e-79 262.8 3.0 8.4e-79 262.8 3.0 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KPA44053.1 - 1.6e-71 238.6 0.1 3.4e-71 237.6 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KPA44053.1 - 5.9e-46 154.8 0.1 1.9e-45 153.1 0.1 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KPA44053.1 - 3.2e-44 149.8 0.3 9.4e-44 148.3 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain SAP18 PF06487.12 KPA44055.1 - 4.5e-43 146.8 0.0 6.2e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 KPA44056.1 - 1.6e-54 183.8 0.0 1.6e-54 183.8 0.0 2.1 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KPA44056.1 - 1.4e-11 43.7 0.5 1.4e-11 43.7 0.5 2.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Caldesmon PF02029.15 KPA44056.1 - 0.0049 15.7 20.1 0.0071 15.2 20.1 1.1 1 0 0 1 1 1 1 Caldesmon RPN7 PF10602.9 KPA44057.1 - 2.5e-46 157.6 0.0 4.6e-46 156.7 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KPA44057.1 - 1.9e-16 60.4 1.4 5.3e-16 59.0 0.3 2.1 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KPA44057.1 - 0.0021 18.0 0.6 2.9 8.2 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat COG2 PF06148.11 KPA44057.1 - 0.05 13.7 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_16 PF13432.6 KPA44057.1 - 0.07 13.8 0.1 1.8 9.2 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat XkdW PF09636.10 KPA44057.1 - 0.17 12.0 0.9 0.3 11.2 0.2 1.8 2 0 0 2 2 2 0 XkdW protein Fungal_trans PF04082.18 KPA44058.1 - 2.7e-25 88.9 0.3 4.5e-25 88.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA44058.1 - 9.7e-11 41.6 13.6 1.9e-10 40.7 13.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer2 PF00111.27 KPA44058.1 - 0.2 11.6 2.9 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Peptidase_M24 PF00557.24 KPA44059.1 - 1.8e-60 204.2 0.2 2.6e-60 203.7 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KPA44059.1 - 3.8e-22 78.3 0.0 7.9e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HTH_Tnp_ISL3 PF13542.6 KPA44059.1 - 0.22 11.0 1.8 0.45 10.0 1.8 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Hexokinase_2 PF03727.16 KPA44059.1 - 0.28 10.6 1.1 0.78 9.1 0.4 1.9 2 0 0 2 2 2 0 Hexokinase Lectin_leg-like PF03388.13 KPA44060.1 - 8.8e-26 90.7 0.0 1.3e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family DUF2353 PF09789.9 KPA44060.1 - 0.00012 21.5 6.7 0.0002 20.8 6.7 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) FUSC PF04632.12 KPA44060.1 - 0.0034 16.0 0.5 0.0045 15.6 0.5 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family Baculo_PEP_C PF04513.12 KPA44060.1 - 0.019 15.0 4.2 0.034 14.2 4.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus F_actin_bind PF08919.10 KPA44060.1 - 0.019 15.1 0.6 0.019 15.1 0.6 2.1 2 0 0 2 2 2 0 F-actin binding PHM7_cyt PF14703.6 KPA44060.1 - 0.048 13.9 0.9 0.084 13.1 0.9 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Occludin_ELL PF07303.13 KPA44060.1 - 0.07 13.9 4.0 0.12 13.1 3.3 1.8 1 1 1 2 2 2 0 Occludin homology domain ATG16 PF08614.11 KPA44060.1 - 0.079 13.2 14.2 0.13 12.4 14.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ABC_tran_CTD PF16326.5 KPA44060.1 - 0.087 13.1 3.0 9.4 6.6 0.0 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 KPA44060.1 - 0.2 12.1 2.1 0.57 10.7 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PCRF PF03462.18 KPA44060.1 - 0.29 11.0 3.1 0.45 10.3 3.1 1.4 1 0 0 1 1 1 0 PCRF domain APG6_N PF17675.1 KPA44060.1 - 0.3 11.6 6.8 0.53 10.8 6.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Prefoldin_2 PF01920.20 KPA44060.1 - 0.61 10.1 6.5 9.8 6.2 6.5 2.4 1 1 0 1 1 1 0 Prefoldin subunit KxDL PF10241.9 KPA44060.1 - 0.72 10.2 9.1 0.36 11.1 5.3 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein TMPIT PF07851.13 KPA44060.1 - 1.1 8.4 4.5 1.6 7.9 4.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein FAM76 PF16046.5 KPA44060.1 - 1.3 8.3 13.1 2.1 7.6 13.1 1.2 1 0 0 1 1 1 0 FAM76 protein Lectin_N PF03954.14 KPA44060.1 - 2.7 7.7 11.4 1.3 8.8 4.3 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Fzo_mitofusin PF04799.13 KPA44060.1 - 3.3 7.2 5.6 11 5.6 5.5 1.8 1 1 0 1 1 1 0 fzo-like conserved region Alg6_Alg8 PF03155.15 KPA44061.1 - 1.4e-177 591.6 27.1 1.6e-177 591.4 27.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.9 KPA44062.1 - 3.9e-39 133.2 0.0 3.9e-39 133.2 0.0 3.3 4 0 0 4 4 4 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KPA44062.1 - 1.2e-17 64.2 0.1 1.2e-17 64.2 0.1 3.5 4 2 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KPA44062.1 - 9.1e-16 57.9 0.1 1.8e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KPA44062.1 - 1.5e-08 33.9 0.0 9.7e-08 31.4 0.0 2.4 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Apc13p PF05839.11 KPA44062.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.5 4 0 0 4 4 4 0 Apc13p protein XRN_M PF17846.1 KPA44062.1 - 4 6.3 10.0 0.12 11.4 0.9 2.6 3 0 0 3 3 3 0 Xrn1 helical domain GST_N_3 PF13417.6 KPA44063.1 - 1.6e-08 34.8 0.0 2.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPA44063.1 - 2.8e-08 34.0 0.0 5.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPA44063.1 - 3.7e-07 30.3 0.0 6.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPA44063.1 - 1.1e-05 25.5 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA44063.1 - 7.9e-05 22.8 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPA44063.1 - 0.00013 21.9 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PPR_2 PF13041.6 KPA44064.1 - 2.1e-22 79.0 0.0 1.4e-10 41.2 0.0 6.8 6 2 3 9 9 9 5 PPR repeat family PPR_3 PF13812.6 KPA44064.1 - 4.6e-14 52.3 0.1 5.7e-06 26.3 0.0 5.3 4 1 3 7 7 7 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 KPA44064.1 - 2.1e-09 36.9 0.0 0.016 14.9 0.0 5.3 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 KPA44064.1 - 2e-08 33.8 0.0 0.025 14.0 0.0 4.1 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KPA44064.1 - 3.3e-08 33.2 0.1 0.17 12.2 0.0 4.9 4 0 0 4 4 4 2 PPR repeat RPM2 PF08579.11 KPA44064.1 - 1.2e-05 25.7 0.0 8.4e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 KPA44064.1 - 0.0029 18.3 2.7 16 6.6 0.0 6.3 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF5388 PF17363.2 KPA44064.1 - 0.02 15.1 0.1 0.88 9.8 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5388) MRP-S27 PF10037.9 KPA44064.1 - 0.088 11.7 0.0 0.89 8.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Mis12 PF05859.12 KPA44065.1 - 3.2e-45 153.5 0.0 5e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein AIM3 PF17096.5 KPA44066.1 - 0.00077 20.3 0.0 0.00077 20.3 0.0 5.4 4 1 1 5 5 5 1 Altered inheritance of mitochondria protein 3 TCTP PF00838.17 KPA44067.1 - 1.2e-69 233.9 2.5 1.3e-69 233.8 2.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein FA_hydroxylase PF04116.13 KPA44068.1 - 4.1e-23 82.2 13.7 4.1e-23 82.2 13.7 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Vac17 PF17321.2 KPA44069.1 - 1.4 8.3 8.6 0.57 9.6 4.5 2.1 2 0 0 2 2 2 0 Vacuole-related protein 17 YL1 PF05764.13 KPA44070.1 - 1.4e-75 254.6 34.5 1.4e-75 254.6 34.5 2.3 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 KPA44070.1 - 8.8e-15 54.2 0.8 2e-14 53.0 0.8 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain BSP_II PF05432.11 KPA44070.1 - 0.0045 16.7 8.9 0.0045 16.7 8.9 2.9 2 1 0 2 2 2 1 Bone sialoprotein II (BSP-II) Ufd2P_core PF10408.9 KPA44070.1 - 0.1 11.2 0.5 0.16 10.6 0.5 1.2 1 0 0 1 1 1 0 Ubiquitin elongating factor core zf-HIT PF04438.16 KPA44070.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 HIT zinc finger FapA PF03961.13 KPA44070.1 - 7.6 5.0 7.1 14 4.2 7.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Lipase_3 PF01764.25 KPA44071.1 - 4.1e-07 29.9 0.0 7.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KPA44071.1 - 0.067 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 KPA44071.1 - 0.087 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.7 KPA44071.1 - 0.091 13.4 2.4 0.31 11.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KPA44071.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family POB3_N PF17292.2 KPA44072.1 - 2.8e-30 104.6 1.0 2.3e-28 98.4 0.2 2.9 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 KPA44072.1 - 6.1e-27 93.3 0.1 8e-26 89.7 0.0 2.7 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KPA44072.1 - 5.4e-22 78.0 0.0 2.8e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC37_M PF08565.11 KPA44072.1 - 0.12 12.3 0.4 0.25 11.3 0.4 1.5 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain PPP4R2 PF09184.11 KPA44072.1 - 8 6.0 18.7 15 5.1 18.7 1.4 1 0 0 1 1 1 0 PPP4R2 HLH PF00010.26 KPA44073.1 - 9.3e-13 47.9 0.0 1.9e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ax_dynein_light PF10211.9 KPA44073.1 - 0.11 12.4 2.1 0.24 11.3 2.1 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain DUF2981 PF11200.8 KPA44073.1 - 0.26 11.0 6.4 0.51 10.0 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SUZ PF12752.7 KPA44074.1 - 1.3e-14 54.6 2.8 1.3e-14 54.6 2.8 3.4 4 0 0 4 4 4 1 SUZ domain R3H PF01424.22 KPA44074.1 - 3.3e-08 33.4 0.1 6.2e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 R3H domain Glyco_transf_8 PF01501.20 KPA44074.1 - 0.23 11.0 0.0 0.34 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 8 JAB PF01398.21 KPA44075.1 - 2e-17 63.2 0.0 3.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KPA44075.1 - 1.6e-16 60.7 0.4 3.9e-16 59.5 0.0 1.8 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 KPA44075.1 - 0.022 14.8 0.0 0.088 12.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) UTP25 PF06862.12 KPA44076.1 - 2.9e-200 666.0 0.1 3.7e-200 665.7 0.1 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KPA44076.1 - 0.0007 19.4 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Mpp10 PF04006.12 KPA44076.1 - 0.096 11.1 22.4 0.14 10.6 22.4 1.2 1 0 0 1 1 1 0 Mpp10 protein Ribosomal_L17 PF01196.19 KPA44077.1 - 1.7e-29 102.5 2.1 1.7e-29 102.5 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L17 Mrpl_C PF18502.1 KPA44077.1 - 0.0015 18.8 0.1 0.0045 17.2 0.0 1.7 2 0 0 2 2 2 1 54S ribosomal protein L8 C-terminal domain AIM5 PF17050.5 KPA44078.1 - 3.9e-24 85.2 2.1 1.5e-23 83.3 2.1 2.1 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 PqqD PF05402.12 KPA44078.1 - 0.15 12.4 1.6 4.7 7.6 0.0 2.8 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) QLQ PF08880.11 KPA44078.1 - 0.21 11.4 0.6 0.37 10.6 0.6 1.3 1 0 0 1 1 1 0 QLQ ALAD PF00490.21 KPA44079.1 - 4e-121 404.1 0.0 5e-121 403.7 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Acyl_transf_3 PF01757.22 KPA44080.1 - 1.7e-43 149.0 28.0 2.4e-43 148.5 28.0 1.2 1 0 0 1 1 1 1 Acyltransferase family Amidohydro_3 PF07969.11 KPA44081.1 - 5.4e-39 135.0 3.0 1.4e-30 107.2 0.6 3.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KPA44081.1 - 0.0023 17.3 0.1 0.23 10.7 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family Abhydrolase_6 PF12697.7 KPA44085.1 - 2.8e-18 67.3 0.2 3.3e-18 67.1 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA44085.1 - 4.7e-08 32.6 0.0 7.5e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 KPA44085.1 - 0.044 13.3 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DEAD PF00270.29 KPA44086.1 - 1.5e-33 116.1 0.0 1.7e-32 112.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA44086.1 - 9.1e-24 84.0 0.0 1.9e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA44086.1 - 0.00026 21.0 0.0 0.00047 20.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KPA44086.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 KPA44086.1 - 0.081 13.3 0.0 1.6 9.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain G-patch PF01585.23 KPA44087.1 - 1.1e-13 50.9 0.1 2.6e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KPA44087.1 - 3.2e-05 23.7 0.1 6.3e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Recep_L_domain PF01030.24 KPA44088.1 - 2.9e-05 24.1 7.2 0.057 13.6 0.6 4.7 1 1 2 4 4 4 4 Receptor L domain LRR_4 PF12799.7 KPA44088.1 - 0.27 11.7 8.4 9.5 6.8 1.9 4.7 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) HhH-GPD PF00730.25 KPA44089.1 - 6.2e-12 45.9 0.0 3.3e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DUF4473 PF14747.6 KPA44089.1 - 0.036 14.6 0.2 0.12 12.9 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Ndc1_Nup PF09531.10 KPA44089.1 - 3.9 6.0 7.1 4.3 5.9 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Anp1 PF03452.14 KPA44090.1 - 5.2e-108 360.4 0.0 6.4e-108 360.1 0.0 1.1 1 0 0 1 1 1 1 Anp1 Snf7 PF03357.21 KPA44091.1 - 4.3e-38 130.6 19.9 4.3e-38 130.6 19.9 2.0 1 1 1 2 2 2 1 Snf7 DUF3138 PF11336.8 KPA44091.1 - 0.13 10.8 11.9 0.039 12.6 6.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Allexi_40kDa PF05549.11 KPA44091.1 - 6.2 6.2 9.5 12 5.4 8.5 1.9 1 1 0 1 1 1 0 Allexivirus 40kDa protein PRKG1_interact PF15898.5 KPA44091.1 - 6.2 7.8 17.6 5.8 7.9 7.8 2.6 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Podoplanin PF05808.11 KPA44092.1 - 0.0091 16.1 15.4 0.0091 16.1 15.4 2.4 2 1 1 3 3 3 1 Podoplanin MFS_1 PF07690.16 KPA44093.1 - 2.1e-05 23.6 37.1 0.00015 20.8 28.3 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KPA44094.1 - 4.8e-53 180.2 0.0 6.6e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA44094.1 - 5.9e-19 68.3 0.2 1.8e-18 66.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KPA44094.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPA44094.1 - 0.15 11.6 0.7 0.26 10.8 0.7 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KPA44094.1 - 0.2 11.2 0.1 0.37 10.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pex24p PF06398.11 KPA44095.1 - 2.5e-92 309.7 0.0 3e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 KPA44095.1 - 0.031 12.6 1.8 0.084 11.2 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) polyprenyl_synt PF00348.17 KPA44096.1 - 1.8e-65 220.5 0.0 2.3e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase MFS_1 PF07690.16 KPA44097.1 - 7.4e-41 140.2 34.2 7.4e-41 140.2 34.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA44097.1 - 4.2e-12 45.7 28.6 2.5e-11 43.1 28.8 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Hydrolase_like PF13242.6 KPA44097.1 - 3.2e-05 23.9 0.0 5.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KPA44097.1 - 7.2e-05 22.9 0.0 0.00015 21.9 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA44097.1 - 0.0097 16.2 0.0 0.074 13.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase YjbE PF11106.8 KPA44097.1 - 1.6 9.0 5.9 3.7 7.8 5.9 1.6 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE CDC14 PF08045.11 KPA44098.1 - 1.7e-130 434.3 0.1 1.9e-130 434.1 0.1 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Asparaginase PF00710.20 KPA44100.1 - 3.3e-29 101.8 0.0 4.6e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KPA44100.1 - 1.6e-19 70.2 0.0 3.2e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain INO80_Ies4 PF08193.11 KPA44102.1 - 1.6e-80 270.6 23.4 2e-80 270.3 23.4 1.2 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.9 KPA44103.1 - 4.3e-31 107.8 0.9 7.8e-31 107.0 0.9 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KPA44103.1 - 1.6e-24 86.3 0.6 1.6e-24 86.3 0.6 1.7 2 0 0 2 2 2 1 SPRY domain LisH PF08513.11 KPA44103.1 - 0.00065 19.6 0.2 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 LisH GST_N_4 PF17172.4 KPA44104.1 - 6.5e-21 74.9 0.0 1e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KPA44104.1 - 4.4e-12 45.6 0.0 1.2e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KPA44104.1 - 9.1e-11 42.1 0.1 1.6e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KPA44104.1 - 0.0018 18.3 0.2 0.0035 17.3 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 KPA44104.1 - 0.0033 17.7 0.2 0.0063 16.8 0.1 1.6 2 0 0 2 2 2 1 SAM35, subunit of SAM coomplex T5orf172 PF10544.9 KPA44106.1 - 1.8e-10 41.3 0.1 3.8e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KPA44106.1 - 7.6e-05 23.3 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 DUF5114 PF17141.4 KPA44106.1 - 0.29 11.7 0.1 0.29 11.7 0.1 2.5 4 0 0 4 4 4 0 Domain of unknown function (DUF5114) DUF3403 PF11883.8 KPA44106.1 - 0.76 9.9 5.6 1.4 9.1 3.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) TPMT PF05724.11 KPA44107.1 - 3.5e-34 118.4 0.0 1.1e-30 106.9 0.0 2.1 1 1 1 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KPA44107.1 - 7.5e-10 38.9 0.0 9.8e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA44107.1 - 7.4e-08 33.0 0.0 1.2e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA44107.1 - 1.4e-06 28.8 0.0 2.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA44107.1 - 0.00025 20.9 0.0 0.0016 18.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA44107.1 - 0.00081 20.1 0.0 0.0021 18.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KPA44107.1 - 0.0088 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB OTU PF02338.19 KPA44108.1 - 6.5e-24 84.8 1.9 1.1e-23 84.1 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KPA44108.1 - 0.0022 17.5 0.1 0.11 11.9 0.0 2.6 2 1 0 2 2 2 1 Peptidase C65 Otubain Nop53 PF07767.11 KPA44108.1 - 4.4 6.6 30.4 6.4 6.1 30.4 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Asp-B-Hydro_N PF05279.11 KPA44108.1 - 6.8 6.7 22.0 12 5.9 22.0 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mcp5_PH PF12814.7 KPA44109.1 - 9e-47 158.2 0.0 2e-46 157.0 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KPA44109.1 - 6.7e-05 23.4 13.5 0.00018 22.1 13.5 1.7 1 0 0 1 1 1 1 Fez1 TPR_MLP1_2 PF07926.12 KPA44109.1 - 0.0054 16.8 17.5 0.13 12.3 6.1 2.4 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 KPA44109.1 - 0.036 13.9 4.4 0.07 13.0 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 KPA44109.1 - 0.72 9.9 13.7 1.3 9.1 13.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 KPA44109.1 - 4.1 7.8 10.7 2.7 8.4 1.2 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) HAD_2 PF13419.6 KPA44110.1 - 4.4e-10 39.9 0.0 6.2e-10 39.4 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA44110.1 - 7.4e-06 25.9 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KPA44110.1 - 0.0001 22.7 0.0 0.00014 22.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ras PF00071.22 KPA44111.1 - 2.3e-51 173.6 0.0 4.5e-51 172.7 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KPA44111.1 - 1.9e-17 63.6 0.0 1.8e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA44111.1 - 0.0014 18.1 0.0 0.004 16.6 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KPA44111.1 - 0.028 14.3 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Abhydrolase_4 PF08386.10 KPA44111.1 - 0.035 14.2 0.0 0.083 13.0 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein FeoB_N PF02421.18 KPA44111.1 - 0.036 13.6 0.1 0.42 10.1 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 KPA44111.1 - 0.092 13.1 0.0 0.15 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KPA44111.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Opy2 PF09463.10 KPA44112.1 - 7.5e-09 35.8 17.0 1.2e-08 35.1 17.0 1.3 1 0 0 1 1 1 1 Opy2 protein Mid2 PF04478.12 KPA44112.1 - 0.0027 17.5 0.1 0.0055 16.5 0.1 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor PTP_tm PF18861.1 KPA44112.1 - 0.13 12.3 0.5 0.25 11.3 0.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Chitin_synth_1 PF01644.17 KPA44113.1 - 3.3e-69 232.0 0.0 4.9e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KPA44113.1 - 1.3e-27 95.5 0.0 2.4e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KPA44113.1 - 6.3e-27 94.4 0.0 5.4e-22 78.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KPA44113.1 - 1.4e-08 34.9 0.2 1.4e-08 34.9 0.2 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KPA44113.1 - 0.0069 16.3 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 UQ_con PF00179.26 KPA44114.1 - 2.5e-37 127.6 0.0 3.2e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IlvN PF07991.12 KPA44115.1 - 1.9e-45 154.4 0.0 3e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KPA44115.1 - 7.1e-41 139.9 0.0 1.1e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KPA44115.1 - 0.018 15.6 0.0 0.046 14.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.25 KPA44116.1 - 3e-61 207.4 0.8 2.2e-60 204.6 0.8 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3343 PF11823.8 KPA44116.1 - 0.18 11.3 0.0 0.54 9.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) MFS_1 PF07690.16 KPA44117.1 - 2.8e-44 151.5 27.4 3.7e-44 151.1 27.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA44117.1 - 1e-09 37.8 5.6 1e-09 37.8 5.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KPA44117.1 - 0.00015 21.2 3.9 0.00015 21.2 3.9 2.7 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 KPA44117.1 - 0.0014 17.3 6.1 0.0014 17.3 6.1 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 KPA44117.1 - 0.0057 15.0 2.5 0.17 10.2 0.3 3.0 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF4492 PF14899.6 KPA44117.1 - 5.5 7.0 6.4 6 6.9 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) Aldedh PF00171.22 KPA44118.1 - 6.8e-20 71.0 11.6 8.9e-14 50.8 8.0 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPA44118.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) URO-D PF01208.17 KPA44118.1 - 0.12 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Germane PF10646.9 KPA44118.1 - 0.15 12.8 0.3 1.2 10.0 0.0 2.4 2 1 1 3 3 3 0 Sporulation and spore germination Rep_fac-A_C PF08646.10 KPA44119.1 - 1.3e-57 193.6 8.2 1.6e-56 190.2 5.5 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KPA44119.1 - 1.2e-37 127.8 1.5 4.5e-37 125.9 0.3 2.6 4 0 0 4 4 4 1 Replication protein A OB domain Rep-A_N PF04057.12 KPA44119.1 - 8.1e-22 77.2 0.0 1.5e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KPA44119.1 - 8.4e-15 54.5 0.3 3.8e-11 42.8 0.0 3.2 2 1 1 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KPA44119.1 - 6.4e-06 26.0 1.9 0.00047 19.9 0.7 2.8 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 zf-like PF04071.12 KPA44119.1 - 0.0079 16.1 1.7 0.021 14.8 1.7 1.7 1 0 0 1 1 1 1 Cysteine-rich small domain DUF223 PF02721.14 KPA44119.1 - 0.026 14.8 0.0 0.079 13.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF223 DLH PF01738.18 KPA44120.1 - 1.2e-22 80.6 0.0 1.1e-21 77.5 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KPA44120.1 - 0.0082 15.8 0.0 0.61 9.7 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KPA44120.1 - 0.0089 15.9 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold ADH_zinc_N PF00107.26 KPA44121.1 - 3.9e-27 94.8 0.2 7.8e-27 93.8 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA44121.1 - 7.2e-23 82.1 0.0 1.1e-22 81.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA44121.1 - 1.4e-08 34.6 0.0 1.9e-07 31.0 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2828 PF11443.8 KPA44121.1 - 0.12 10.5 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1510 PF07423.11 KPA44121.1 - 0.14 12.3 0.1 9.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) AMP-binding PF00501.28 KPA44123.1 - 1e-69 235.2 0.0 1.4e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KPA44123.1 - 6.3e-20 70.8 0.4 6.3e-20 70.8 0.4 2.6 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KPA44123.1 - 1.3e-15 58.1 0.0 2.8e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BRCT_2 PF16589.5 KPA44124.1 - 8.4e-09 35.7 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KPA44124.1 - 4.7e-05 23.7 0.0 8.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KPA44124.1 - 0.00048 20.0 0.1 0.0018 18.2 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 KPA44124.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain KilA-N PF04383.13 KPA44125.1 - 8e-05 22.5 0.0 0.0023 17.8 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Fungal_TACC PF12709.7 KPA44126.1 - 2.2e-10 40.8 3.4 2.2e-10 40.8 3.4 4.9 2 2 2 5 5 5 2 Fungal Transforming acidic coiled-coil (TACC) proteins TACC_C PF05010.14 KPA44126.1 - 0.018 14.9 40.3 0.022 14.5 30.7 2.4 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GIT_CC PF16559.5 KPA44126.1 - 0.049 13.5 0.2 0.049 13.5 0.2 4.1 4 1 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 KPA44126.1 - 0.093 12.1 25.9 0.086 12.2 10.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Amidohydro_2 PF04909.14 KPA44127.1 - 5.6e-26 92.0 0.3 8.9e-26 91.3 0.3 1.3 1 1 0 1 1 1 1 Amidohydrolase AMPK1_CBM PF16561.5 KPA44128.1 - 0.0036 17.5 0.0 0.0077 16.4 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Peroxin-3 PF04882.12 KPA44128.1 - 0.24 10.4 8.3 0.3 10.0 8.3 1.2 1 0 0 1 1 1 0 Peroxin-3 Sec3_C PF09763.9 KPA44128.1 - 0.6 8.4 6.3 0.67 8.3 6.3 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Hid1 PF12722.7 KPA44128.1 - 0.62 8.1 5.5 0.75 7.9 5.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GEMIN8 PF15348.6 KPA44128.1 - 1.1 9.5 8.8 2.1 8.6 8.8 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Zip PF02535.22 KPA44128.1 - 1.3 8.2 5.1 1.4 8.0 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KPA44128.1 - 1.6 7.4 8.0 2 7.1 8.0 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 KPA44128.1 - 1.7 7.3 11.6 2.3 6.9 11.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tmemb_cc2 PF10267.9 KPA44128.1 - 3 6.9 7.0 3.4 6.7 7.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RNase_T PF00929.24 KPA44129.1 - 6.4e-08 33.3 0.0 3.8e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 Exonuclease TRP PF06011.12 KPA44130.1 - 6.2e-40 137.2 15.9 1.2e-38 133.0 15.9 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KPA44130.1 - 6.4e-22 78.4 0.0 9.9e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Ydc2-catalyt PF09159.10 KPA44131.1 - 0.024 14.4 1.5 0.11 12.2 0.2 2.0 1 1 1 2 2 2 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 CENP-T_C PF15511.6 KPA44131.1 - 0.073 13.2 0.1 0.16 12.1 0.1 1.7 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold HATPase_c_3 PF13589.6 KPA44132.1 - 2.8e-10 40.1 0.1 5.8e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KPA44132.1 - 7.1e-08 32.9 0.1 1.9e-07 31.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KPA44132.1 - 4e-06 26.5 0.0 9.2e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DMRL_synthase PF00885.19 KPA44133.1 - 8.9e-57 190.9 0.1 1.1e-56 190.6 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DNA_pol_phi PF04931.13 KPA44134.1 - 2.3 6.2 6.5 3.4 5.6 6.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cation_efflux PF01545.21 KPA44135.1 - 6.3e-21 75.0 9.7 8.3e-21 74.6 9.7 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KPA44135.1 - 1.8e-06 28.0 0.0 3.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Adeno_E3B PF03376.14 KPA44135.1 - 0.14 12.4 0.2 0.49 10.7 0.2 1.9 1 0 0 1 1 1 0 Adenovirus E3B protein PI3_PI4_kinase PF00454.27 KPA44136.1 - 3.3e-39 135.2 0.0 8.7e-37 127.3 0.0 2.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KPA44136.1 - 7.8e-24 84.1 0.0 1.8e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Symplekin_C PF12295.8 KPA44136.1 - 0.029 14.4 0.0 0.086 12.9 0.0 1.8 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal Proteasome PF00227.26 KPA44137.1 - 7e-28 97.4 0.4 8.9e-27 93.8 0.2 2.2 2 1 0 2 2 2 1 Proteasome subunit YTH PF04146.15 KPA44138.1 - 5.8e-62 208.5 0.0 1e-61 207.7 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KPA44138.1 - 0.0028 17.4 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPA44138.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif HSP20 PF00011.21 KPA44139.1 - 3.5e-17 62.4 0.3 1.8e-12 47.3 0.7 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KPA44139.1 - 9.7e-06 25.1 0.0 0.00011 21.6 0.0 2.2 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DDE_Tnp_1_2 PF13586.6 KPA44139.1 - 0.058 13.8 0.3 0.18 12.2 0.1 1.8 2 0 0 2 2 2 0 Transposase DDE domain RR_TM4-6 PF06459.12 KPA44139.1 - 0.13 12.0 8.5 1.2 8.9 0.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Rad51 PF08423.11 KPA44140.1 - 1.7e-126 420.7 0.0 2e-126 420.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KPA44140.1 - 1.7e-08 34.3 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KPA44140.1 - 7.3e-08 32.2 0.0 1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KPA44140.1 - 5.2e-06 26.0 0.0 1.2e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KPA44140.1 - 1.9e-05 25.1 0.1 4.7e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DnaB_C PF03796.15 KPA44140.1 - 0.012 15.0 0.0 0.05 12.9 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ssDNA_TraI_N PF18272.1 KPA44140.1 - 0.1 12.6 0.2 0.59 10.2 0.1 2.1 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 KPA44140.1 - 0.17 11.0 0.2 0.82 8.7 0.1 1.9 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.8 KPA44141.1 - 7.1e-130 434.2 0.1 9e-130 433.8 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF2448 PF10476.9 KPA44141.1 - 0.046 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) ApoA-II PF04711.13 KPA44141.1 - 0.15 12.2 0.0 0.54 10.4 0.0 1.9 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) Vps26 PF03643.15 KPA44142.1 - 8.7e-130 431.7 0.6 1e-129 431.4 0.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KPA44142.1 - 0.00042 20.4 0.7 0.28 11.2 0.7 3.6 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain IL17R_D_N PF16742.5 KPA44142.1 - 0.065 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Ribosomal_L6 PF00347.23 KPA44143.1 - 5.4e-29 100.7 7.0 2e-14 54.0 2.9 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF4690 PF15756.5 KPA44144.1 - 0.00082 19.9 1.5 0.0021 18.6 1.5 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Glycophorin_A PF01102.18 KPA44144.1 - 0.0036 17.5 0.0 0.0092 16.2 0.0 1.7 2 0 0 2 2 2 1 Glycophorin A Podoplanin PF05808.11 KPA44144.1 - 0.03 14.5 8.3 0.023 14.8 7.0 1.6 1 1 0 1 1 1 0 Podoplanin Mid2 PF04478.12 KPA44144.1 - 0.059 13.2 0.5 0.73 9.7 0.1 2.5 1 1 0 2 2 2 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 KPA44144.1 - 0.092 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family CYYR1 PF10873.8 KPA44144.1 - 0.39 11.2 0.0 0.39 11.2 0.0 3.4 3 0 0 3 3 3 0 Cysteine and tyrosine-rich protein 1 V-ATPase_H_N PF03224.14 KPA44145.1 - 5.7e-73 245.9 0.0 7.6e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KPA44145.1 - 9.6e-36 122.5 0.0 8.1e-35 119.5 0.0 2.5 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.6 KPA44145.1 - 0.0024 18.2 0.3 0.29 11.5 0.0 2.9 2 1 0 2 2 2 1 HEAT repeats Arm PF00514.23 KPA44145.1 - 0.082 13.0 0.1 26 5.1 0.0 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat GCV_T PF01571.21 KPA44146.1 - 4.6e-77 258.9 0.0 5.7e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KPA44146.1 - 1.8e-22 79.0 0.2 4.3e-22 77.8 0.2 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 KPA44146.1 - 0.074 13.2 0.1 6.2 7.0 0.0 3.0 2 1 1 3 3 3 0 Sarcosine oxidase, gamma subunit family Metallophos PF00149.28 KPA44147.1 - 3.8e-11 43.9 0.7 8.1e-11 42.8 0.7 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_5 PF13854.6 KPA44148.1 - 6.1e-18 64.4 6.3 2.8e-08 33.6 0.1 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 KPA44148.1 - 1.1e-11 44.5 2.4 0.24 11.5 0.0 5.7 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KPA44148.1 - 2.8e-11 43.4 9.0 0.011 16.0 0.0 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KPA44148.1 - 3.2e-11 43.1 5.9 0.079 13.3 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KPA44148.1 - 6e-10 38.5 4.8 0.0035 16.9 0.1 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KPA44148.1 - 1.5e-05 24.8 3.9 0.00076 19.4 0.1 4.4 5 1 0 5 5 5 1 Kelch motif Phage_holin_2_4 PF16082.5 KPA44148.1 - 0.15 11.8 0.4 0.49 10.2 0.4 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like GFA PF04828.14 KPA44151.1 - 3.1e-15 56.3 0.2 9.2e-07 29.1 0.1 2.3 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF1765 PF08578.10 KPA44152.1 - 2.4e-41 141.1 4.0 5.8e-41 139.9 4.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) FSA_C PF10479.9 KPA44152.1 - 7.8 4.5 10.6 12 3.8 10.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PhoD PF09423.10 KPA44153.1 - 2.1e-07 30.3 0.8 0.00067 18.8 0.1 2.7 2 1 0 2 2 2 2 PhoD-like phosphatase Aldedh PF00171.22 KPA44154.1 - 1.3e-104 350.3 0.1 1.7e-104 349.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HLH PF00010.26 KPA44155.1 - 1.1e-13 50.9 0.2 2.7e-13 49.6 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Red1 PF07964.11 KPA44155.1 - 0.4 8.9 8.4 0.55 8.4 8.4 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Per1 PF04080.13 KPA44156.1 - 3.9e-104 347.9 16.1 4.9e-104 347.6 16.1 1.1 1 0 0 1 1 1 1 Per1-like family Pkinase PF00069.25 KPA44157.1 - 1.7e-48 165.3 0.0 2.6e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA44157.1 - 1.1e-21 77.4 0.0 1.7e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KPA44157.1 - 0.0076 15.9 0.1 0.029 13.9 0.0 1.9 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 KPA44157.1 - 0.17 11.5 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KPA44157.1 - 0.38 9.5 0.0 0.38 9.5 0.0 2.4 2 1 0 2 2 2 0 Fungal protein kinase Ribosomal_L21p PF00829.21 KPA44158.1 - 2.3e-13 50.3 0.0 2.9e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ribosomal_S8e PF01201.22 KPA44159.1 - 1.1e-46 158.4 2.9 1.8e-46 157.7 2.9 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e Red1 PF07964.11 KPA44159.1 - 3.9 5.6 9.9 4.7 5.3 9.9 1.0 1 0 0 1 1 1 0 Rec10 / Red1 PrmA PF06325.13 KPA44160.1 - 3e-10 40.0 0.0 4.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KPA44160.1 - 4.2e-10 40.2 0.0 1e-09 38.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA44160.1 - 3.1e-09 36.8 0.0 5.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA44160.1 - 8.1e-07 29.6 0.0 2.4e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KPA44160.1 - 1.8e-06 27.2 0.1 2.6e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 KPA44160.1 - 7.8e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KPA44160.1 - 0.00012 22.0 0.1 0.0002 21.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA44160.1 - 0.0022 18.7 0.0 0.0041 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA44160.1 - 0.0029 17.2 0.1 0.0057 16.2 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KPA44160.1 - 0.0052 16.1 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5_C PF17286.2 KPA44160.1 - 0.032 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Methyltransf_32 PF13679.6 KPA44160.1 - 0.04 13.9 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 KPA44160.1 - 0.042 13.7 0.1 0.076 12.9 0.1 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PGM_PMM_I PF02878.16 KPA44161.1 - 2.5e-16 59.7 0.1 2e-07 30.8 0.0 3.0 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KPA44161.1 - 6.4e-11 42.3 0.3 2.9e-10 40.2 0.3 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KPA44161.1 - 0.0017 18.5 0.1 0.0067 16.6 0.1 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KPA44161.1 - 0.0033 18.0 0.2 0.051 14.2 0.2 2.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ERCC4 PF02732.15 KPA44162.1 - 4e-24 85.6 0.0 7.5e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 KPA44162.1 - 0.00057 20.2 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Pilin_PilA PF14245.6 KPA44162.1 - 0.02 14.9 0.1 8.7 6.3 0.0 3.2 3 0 0 3 3 3 0 Type IV pilin PilA HHH_5 PF14520.6 KPA44162.1 - 0.039 14.5 0.0 0.57 10.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain Lum_binding PF00677.17 KPA44163.1 - 5.1e-46 154.6 2.4 1.9e-22 79.0 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain TPR_16 PF13432.6 KPA44164.1 - 1.9e-12 47.6 1.8 7.2e-06 26.6 1.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KPA44164.1 - 7.9e-12 45.3 4.6 2.2e-05 24.6 1.5 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPA44164.1 - 1.6e-10 40.2 0.9 0.0017 18.3 0.0 5.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KPA44164.1 - 2.5e-09 37.2 4.8 0.22 12.4 0.1 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPA44164.1 - 5.5e-09 36.4 7.5 0.0018 18.7 0.9 4.3 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KPA44164.1 - 5.7e-09 35.5 0.0 0.0037 17.3 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KPA44164.1 - 5.9e-09 35.7 4.0 5.9e-05 22.6 0.1 2.7 2 1 0 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 KPA44164.1 - 7.7e-07 28.7 2.1 0.09 12.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KPA44164.1 - 3.2e-06 26.8 7.5 0.44 10.5 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 KPA44164.1 - 1e-05 25.3 2.3 0.0061 16.3 0.3 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 KPA44164.1 - 1.2e-05 24.9 0.5 0.0098 15.7 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KPA44164.1 - 0.00024 20.7 0.1 0.2 11.4 0.0 4.3 5 0 0 5 5 5 1 TPR repeat TPR_6 PF13174.6 KPA44164.1 - 0.001 19.5 4.0 4.6 8.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KPA44164.1 - 0.003 18.0 8.8 2.1 9.2 0.4 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KPA44164.1 - 0.0071 16.5 4.4 2.7 8.2 0.1 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA44164.1 - 0.0078 16.4 0.1 4.5 7.6 0.0 3.7 3 2 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 KPA44164.1 - 0.013 15.1 4.5 0.5 10.0 0.3 3.7 2 2 2 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 KPA44164.1 - 0.016 15.6 0.0 23 5.7 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF4363 PF14276.6 KPA44164.1 - 9.2 6.4 9.4 34 4.6 1.8 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4363) RWD PF05773.22 KPA44165.1 - 7e-24 84.4 0.5 1.1e-23 83.7 0.5 1.3 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KPA44165.1 - 3.5e-05 24.2 8.0 3.8e-05 24.1 6.2 1.9 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 ApoLp-III PF07464.11 KPA44165.1 - 0.012 15.7 0.6 0.023 14.8 0.6 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF2852 PF11014.8 KPA44165.1 - 0.035 14.3 1.7 0.053 13.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) UQ_con PF00179.26 KPA44165.1 - 0.16 11.6 0.3 0.23 11.1 0.3 1.4 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme CPL PF08144.11 KPA44166.1 - 2.5e-48 164.1 0.1 3.1e-46 157.3 0.0 3.3 3 1 0 3 3 3 1 CPL (NUC119) domain CTI PF06934.11 KPA44166.1 - 0.052 12.1 0.0 0.084 11.4 0.0 1.2 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) CDK2AP PF09806.9 KPA44166.1 - 2.1 8.4 5.7 20 5.1 0.0 2.8 2 1 1 3 3 3 0 Cyclin-dependent kinase 2-associated protein BatA PF07584.11 KPA44167.1 - 0.1 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF202 PF02656.15 KPA44167.1 - 0.16 12.4 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF2235 PF09994.9 KPA44168.1 - 5.4e-80 268.8 0.0 7.5e-80 268.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) RNA_pol_Rpb4 PF03874.16 KPA44169.1 - 3.5e-26 92.0 2.6 4.5e-26 91.6 2.6 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Spexin PF15171.6 KPA44169.1 - 0.032 14.4 0.1 0.068 13.4 0.1 1.6 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin TROVE PF05731.11 KPA44169.1 - 0.035 13.2 0.1 0.04 13.0 0.1 1.1 1 0 0 1 1 1 0 TROVE domain Sybindin PF04099.12 KPA44170.1 - 4e-39 133.8 0.0 4.9e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KPA44170.1 - 8.7e-08 32.4 0.1 1.1e-07 32.0 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.6 KPA44171.1 - 3.3e-26 92.0 0.3 7.1e-26 91.0 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KPA44171.1 - 2e-12 47.7 0.3 2.5e-12 47.4 0.3 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KPA44171.1 - 1.9e-08 34.3 0.0 3.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KPA44171.1 - 0.012 15.5 1.4 0.036 14.0 1.4 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.9 KPA44172.1 - 1.1e-20 73.0 5.3 1.9e-20 72.2 5.3 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal SUI1 PF01253.22 KPA44173.1 - 3e-23 82.2 0.4 3e-23 82.2 0.4 2.0 2 1 0 2 2 2 1 Translation initiation factor SUI1 Methyltransf_11 PF08241.12 KPA44174.1 - 1.5e-12 48.0 0.0 4.4e-12 46.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA44174.1 - 6.1e-06 26.8 0.0 1.7e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA44174.1 - 0.033 14.0 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KPA44174.1 - 0.042 14.6 0.0 0.1 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KPA44174.1 - 0.074 12.4 0.0 0.36 10.1 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KPA44174.1 - 0.085 12.7 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Band_7 PF01145.25 KPA44175.1 - 1.1e-22 80.8 5.1 2e-22 80.0 5.1 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family ubiquitin PF00240.23 KPA44176.1 - 1.4e-24 85.6 0.4 1.6e-24 85.4 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KPA44176.1 - 4.7e-13 48.8 0.3 5.1e-13 48.6 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KPA44176.1 - 0.0014 19.1 0.1 0.0018 18.7 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KPA44176.1 - 0.012 15.7 0.1 0.036 14.2 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KPA44176.1 - 0.052 13.5 0.0 0.061 13.3 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Elongin_A PF06881.11 KPA44177.1 - 1.2e-28 99.7 2.2 1.9e-28 99.0 2.2 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A TFIIF_beta_N PF17683.1 KPA44178.1 - 1.5e-32 113.1 0.0 2.5e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KPA44178.1 - 1.1e-28 99.2 0.5 1.9e-28 98.4 0.5 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain SurA_N_3 PF13624.6 KPA44178.1 - 0.017 14.9 0.1 0.9 9.3 0.0 2.2 2 0 0 2 2 2 0 SurA N-terminal domain HAD PF12710.7 KPA44179.1 - 1.5e-14 54.8 0.1 1.1e-13 52.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA44179.1 - 0.00012 22.5 0.0 0.00025 21.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KPA44179.1 - 0.0018 18.4 1.4 0.85 9.7 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KPA44179.1 - 0.014 14.8 0.2 0.66 9.3 0.1 2.4 2 1 0 2 2 2 0 Putative Phosphatase CorA PF01544.18 KPA44180.1 - 0.0016 17.8 3.6 0.0063 15.9 3.6 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein MIX PF18529.1 KPA44180.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins Glyco_hydro_18 PF00704.28 KPA44181.1 - 5.7e-77 259.5 4.8 9.7e-77 258.8 4.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MAJIN PF15077.6 KPA44181.1 - 0.34 10.7 3.2 0.75 9.5 3.2 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein SWI-SNF_Ssr4 PF08549.10 KPA44182.1 - 3.7e-296 984.6 0.1 4.5e-296 984.3 0.1 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) 6PGD PF00393.19 KPA44183.1 - 5.4e-127 423.1 0.0 6.7e-127 422.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KPA44183.1 - 9.6e-51 172.1 0.0 1.6e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KPA44183.1 - 0.068 13.4 0.1 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DNA_pol3_beta PF00712.19 KPA44183.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain RRM_1 PF00076.22 KPA44184.1 - 3.2e-17 62.1 0.0 5.5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytotoxic PF09000.10 KPA44184.1 - 0.0075 16.6 0.2 0.0075 16.6 0.2 2.1 2 1 0 2 2 2 1 Cytotoxic TPT PF03151.16 KPA44185.1 - 2.2e-21 76.5 10.9 3.8e-21 75.7 10.9 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KPA44185.1 - 0.00015 22.0 34.4 0.0024 18.0 16.0 2.7 2 1 0 2 2 2 2 EamA-like transporter family CrgA PF06781.12 KPA44185.1 - 0.15 12.1 0.9 0.54 10.4 0.0 2.4 2 0 0 2 2 2 0 Cell division protein CrgA Glyco_hydro_15 PF00723.21 KPA44186.1 - 9.6e-53 179.5 0.0 7.5e-50 170.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 MOSC PF03473.17 KPA44187.1 - 3.8e-38 130.5 0.0 6.4e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KPA44187.1 - 3.3e-20 72.2 0.0 6.1e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 KPA44187.1 - 2.4e-19 69.5 0.0 3.6e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF3546 PF12066.8 KPA44188.1 - 1.1e-32 112.4 2.5 1.1e-32 112.4 2.5 2.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KPA44188.1 - 1.2e-16 61.7 0.3 3.8e-16 60.0 0.3 1.9 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KPA44188.1 - 1.7e-12 46.9 0.1 4.2e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) TSP_NTD PF17804.1 KPA44188.1 - 0.17 12.1 0.1 0.17 12.1 0.1 2.4 4 0 0 4 4 4 0 Tail specific protease N-terminal domain PEP-utilisers_N PF05524.13 KPA44188.1 - 0.18 12.0 2.6 2.4 8.4 0.9 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal G-patch PF01585.23 KPA44189.1 - 4.1e-05 23.4 0.0 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 G-patch domain DUF936 PF06075.12 KPA44189.1 - 0.28 10.0 37.8 0.38 9.6 37.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Macoilin PF09726.9 KPA44189.1 - 0.76 8.3 31.1 1 7.8 31.1 1.2 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 KPA44189.1 - 1.2 6.2 26.9 1.5 5.9 26.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer tRNA-synt_2d PF01409.20 KPA44191.1 - 1e-86 290.4 0.0 1.4e-86 290.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KPA44191.1 - 1.3e-17 63.8 1.8 3.5e-17 62.4 0.9 2.2 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KPA44191.1 - 7.3e-07 28.8 0.0 0.008 15.6 0.0 3.1 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KPA44191.1 - 4e-05 22.9 0.1 0.00088 18.4 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 KPA44191.1 - 0.00022 21.1 1.6 0.00049 20.0 1.6 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 2 DUF1938 PF09153.10 KPA44191.1 - 0.075 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) DUF1746 PF08508.10 KPA44192.1 - 8.1e-40 135.7 2.8 1.2e-39 135.2 2.8 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RTC_insert PF05189.13 KPA44193.1 - 1.4e-30 105.9 0.0 2.4e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KPA44193.1 - 1.6e-28 99.4 0.3 2e-28 99.1 0.3 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase PPR_2 PF13041.6 KPA44194.1 - 5.3e-10 39.3 0.0 2.3e-06 27.7 0.0 4.1 4 0 0 4 4 4 1 PPR repeat family PPR_3 PF13812.6 KPA44194.1 - 0.00012 22.1 0.0 0.19 11.8 0.0 3.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain TPR_19 PF14559.6 KPA44194.1 - 0.00072 20.0 0.6 2.4 8.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR PF01535.20 KPA44194.1 - 0.00089 19.4 0.0 2.8 8.4 0.0 3.8 3 0 0 3 3 3 1 PPR repeat TPR_6 PF13174.6 KPA44194.1 - 0.0022 18.5 2.1 3.6 8.4 0.1 4.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPA44194.1 - 0.0044 17.0 0.1 3.6 7.9 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPA44194.1 - 0.0063 17.2 0.0 5 8.2 0.0 3.8 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR_1 PF12854.7 KPA44194.1 - 0.012 15.3 0.0 5 6.9 0.0 3.1 3 0 0 3 3 3 0 PPR repeat TPR_16 PF13432.6 KPA44194.1 - 0.018 15.7 0.1 0.87 10.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KPA44194.1 - 0.028 14.1 0.0 3.6 7.3 0.0 2.8 2 0 0 2 2 2 0 26S proteasome subunit RPN7 PilJ PF13675.6 KPA44194.1 - 0.05 13.6 0.5 18 5.4 0.0 3.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term TPR_7 PF13176.6 KPA44194.1 - 0.054 13.5 0.2 17 5.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat AEP1 PF17049.5 KPA44194.1 - 0.06 12.4 0.0 7.1 5.6 0.0 2.3 2 0 0 2 2 2 0 ATPase expression protein 1 P53_TAD PF08563.11 KPA44194.1 - 0.47 10.0 6.1 0.23 11.0 0.2 2.7 2 0 0 2 2 2 0 P53 transactivation motif GREB1 PF15782.5 KPA44195.1 - 0.36 7.9 9.2 0.41 7.7 9.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EVI2A PF05399.11 KPA44195.1 - 4.7 6.7 11.1 11 5.5 11.1 1.5 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) NuA4 PF09340.10 KPA44196.1 - 2.1e-23 82.0 0.9 3.1e-23 81.5 0.0 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Peptidase_S9 PF00326.21 KPA44197.1 - 5e-55 186.3 0.8 7.7e-55 185.6 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family PD40 PF07676.12 KPA44197.1 - 1.9e-05 24.5 0.1 0.00027 20.8 0.0 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Esterase PF00756.20 KPA44197.1 - 0.011 15.4 0.2 0.028 14.1 0.2 1.7 1 1 0 1 1 1 0 Putative esterase Bromo_TP PF07524.13 KPA44198.1 - 8.5e-09 35.3 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 KPA44198.1 - 2.4e-05 24.4 0.0 3.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PWI PF01480.17 KPA44199.1 - 9e-31 106.0 0.1 1.3e-30 105.5 0.1 1.2 1 0 0 1 1 1 1 PWI domain Nas2_N PF18265.1 KPA44200.1 - 1.4e-28 98.6 0.0 2e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KPA44200.1 - 2.3e-07 30.5 0.0 4.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KPA44200.1 - 9.1e-07 29.1 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KPA44200.1 - 0.00016 22.0 0.0 0.00035 20.9 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KPA44200.1 - 0.00027 21.2 0.0 0.0005 20.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Colipase-like PF15083.6 KPA44201.1 - 0.15 12.2 3.4 0.21 11.7 3.4 1.2 1 0 0 1 1 1 0 Colipase-like Sulfotransfer_4 PF17784.1 KPA44202.1 - 2e-62 210.8 0.0 2.4e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPA44202.1 - 4.8e-05 23.8 0.5 0.0029 18.0 0.0 3.0 1 1 2 3 3 3 1 Sulfotransferase family DHDPS PF00701.22 KPA44203.1 - 3.9e-46 157.1 0.0 5.1e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FlpD PF02662.16 KPA44203.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit RrnaAD PF00398.20 KPA44204.1 - 9.6e-60 201.9 0.0 1.3e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KPA44204.1 - 4.1e-05 24.2 0.0 0.00017 22.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KPA44204.1 - 0.00043 19.7 0.0 0.00067 19.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KPA44204.1 - 0.0045 17.6 0.0 0.012 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA44204.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 KPA44204.1 - 0.021 13.9 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.19 KPA44204.1 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KPA44204.1 - 0.094 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Peptidase_M20 PF01546.28 KPA44205.1 - 8.2e-30 104.0 0.0 1.1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPA44205.1 - 1.7e-11 44.0 0.0 3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF2552 PF10827.8 KPA44206.1 - 0.099 12.8 0.3 0.62 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) DUF521 PF04412.13 KPA44207.1 - 7.4e-144 479.4 0.0 2.1e-143 477.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF521) DUF126 PF01989.16 KPA44207.1 - 1.2e-31 108.3 0.0 2.9e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 Aconitase X swivel domain Aconitase PF00330.20 KPA44207.1 - 0.16 10.9 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) Peptidase_M20 PF01546.28 KPA44208.1 - 2.5e-19 69.8 4.3 1.8e-18 67.0 4.3 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPA44208.1 - 4.2e-19 68.5 0.0 9.1e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KPA44208.1 - 0.022 14.4 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 IF-2B PF01008.17 KPA44209.1 - 7.7e-80 268.1 2.6 8.9e-80 267.9 2.6 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF3606 PF12244.8 KPA44209.1 - 0.017 15.0 0.5 0.99 9.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) DUF2680 PF10925.8 KPA44209.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) TRAPPC10 PF12584.8 KPA44210.1 - 1.2e-22 80.3 0.2 4.3e-22 78.5 0.1 2.0 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 KPA44210.1 - 0.00014 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 Cupin_7 PF12973.7 KPA44211.1 - 1.1e-11 44.4 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF2205 PF10224.9 KPA44212.1 - 2.2e-34 117.3 0.9 3.2e-34 116.7 0.9 1.3 1 0 0 1 1 1 1 Short coiled-coil protein Methyltransf_24 PF13578.6 KPA44213.1 - 9.9e-12 45.8 0.0 1.7e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KPA44213.1 - 1.5e-08 34.1 0.0 4.1e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase DUF3885 PF13021.6 KPA44213.1 - 0.0064 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3885) PI-PLC-X PF00388.19 KPA44214.1 - 4.5e-45 152.8 0.0 6.8e-45 152.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KPA44214.1 - 3e-35 121.0 0.0 4.7e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KPA44214.1 - 0.0069 16.7 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain CENP-B_dimeris PF09026.10 KPA44214.1 - 0.011 16.1 1.2 0.029 14.7 1.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Stealth_CR1 PF17101.5 KPA44215.1 - 0.014 15.1 13.3 5.6 6.8 0.2 5.9 6 0 0 6 6 6 0 Stealth protein CR1, conserved region 1 Trypan_PARP PF05887.11 KPA44215.1 - 1.8 8.6 33.7 1.8e+04 -6.3 33.7 3.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PknG_rubred PF16919.5 KPA44215.1 - 9.3 6.4 11.7 6.3 7.0 1.7 3.1 3 0 0 3 3 3 0 Protein kinase G rubredoxin domain Phytase PF02333.15 KPA44216.1 - 2.5e-74 250.5 1.1 2.6e-70 237.3 0.1 2.3 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 KPA44216.1 - 1.8e-08 34.6 35.3 0.00028 21.2 12.4 2.6 2 0 0 2 2 2 2 EGF-like domain S_locus_glycop PF00954.20 KPA44216.1 - 0.003 18.1 4.1 0.003 18.1 4.1 2.9 2 1 1 3 3 3 1 S-locus glycoprotein domain FAD_binding_3 PF01494.19 KPA44217.1 - 3e-17 62.9 0.0 3.3e-11 43.1 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPA44217.1 - 5e-06 26.6 0.4 1.2e-05 25.4 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA44217.1 - 0.0017 17.6 0.1 0.17 11.1 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPA44217.1 - 0.0072 15.5 0.4 0.01 15.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.21 KPA44217.1 - 0.015 14.7 0.2 0.025 14.0 0.2 1.4 1 0 0 1 1 1 0 ThiF family DAO PF01266.24 KPA44217.1 - 0.024 14.2 1.4 0.05 13.2 1.4 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KPA44217.1 - 0.091 12.0 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family CYSTM PF12734.7 KPA44218.1 - 0.01 16.1 64.8 1.6e+02 2.7 48.7 4.6 2 1 0 2 2 2 0 Cysteine-rich TM module stress tolerance eIF3g PF12353.8 KPA44219.1 - 6.2e-44 149.4 1.1 1.1e-43 148.6 1.1 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KPA44219.1 - 3e-15 55.8 0.1 6e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KPA44219.1 - 0.031 14.6 0.1 0.061 13.7 0.1 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 PEMT PF04191.13 KPA44220.1 - 1.5e-58 195.7 8.6 1e-35 122.3 1.3 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 KPA44220.1 - 0.091 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Lactonase PF10282.9 KPA44221.1 - 5.6e-77 259.3 0.0 6.6e-77 259.1 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Zn_clus PF00172.18 KPA44222.1 - 4.8e-09 36.2 7.9 4.8e-09 36.2 7.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBR PF01485.21 KPA44223.1 - 9.6e-12 45.0 32.3 3.6e-08 33.5 6.2 3.3 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KPA44223.1 - 0.021 15.1 9.2 0.021 15.1 9.2 3.5 3 0 0 3 3 3 0 Ring finger domain zf-RING_UBOX PF13445.6 KPA44223.1 - 0.088 12.8 7.8 0.32 11.0 7.8 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DUF676 PF05057.14 KPA44224.1 - 1.7e-41 142.1 0.1 3.1e-27 95.5 0.0 3.2 2 1 0 2 2 2 2 Putative serine esterase (DUF676) Mit_KHE1 PF10173.9 KPA44225.1 - 1.5e-50 172.0 0.0 2.1e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Svf1_C PF17187.4 KPA44227.1 - 1.1e-63 214.0 0.3 3.1e-63 212.5 0.1 1.8 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KPA44227.1 - 2.2e-55 187.2 0.0 3.2e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain GATA PF00320.27 KPA44228.1 - 1.1e-14 53.7 2.5 2.4e-14 52.6 2.5 1.6 1 0 0 1 1 1 1 GATA zinc finger Macoilin PF09726.9 KPA44228.1 - 0.00041 19.0 8.5 0.00057 18.6 8.5 1.2 1 0 0 1 1 1 1 Macoilin family GAS PF13851.6 KPA44228.1 - 0.0045 16.4 3.5 0.0045 16.4 3.5 2.1 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding ArfGap PF01412.18 KPA44228.1 - 0.051 13.6 1.7 0.059 13.5 0.1 1.8 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf FPP PF05911.11 KPA44228.1 - 0.64 8.1 12.1 0.25 9.5 9.3 1.5 1 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil TPD52 PF04201.15 KPA44228.1 - 0.72 9.5 7.4 3 7.4 4.1 2.4 2 0 0 2 2 2 0 Tumour protein D52 family DUF4472 PF14739.6 KPA44228.1 - 0.77 10.5 15.9 2.6 8.8 10.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) APG6_N PF17675.1 KPA44228.1 - 0.94 10.0 18.6 0.32 11.5 14.0 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 KPA44228.1 - 1.1 9.9 19.8 6.2 7.5 14.1 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SHE3 PF17078.5 KPA44228.1 - 2 8.0 12.1 0.31 10.7 7.0 2.1 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 FapA PF03961.13 KPA44228.1 - 2.3 6.7 4.8 4.2 5.9 4.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 KPA44228.1 - 2.8 6.7 16.0 0.57 9.0 9.9 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Allexi_40kDa PF05549.11 KPA44228.1 - 6.3 6.2 6.2 10 5.6 2.7 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein AbiEi_4 PF13338.6 KPA44229.1 - 0.093 12.9 3.1 0.12 12.6 2.3 1.6 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Acetyltransf_1 PF00583.25 KPA44230.1 - 1.5e-07 31.6 0.0 2.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA44230.1 - 0.061 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ABC_tran PF00005.27 KPA44231.1 - 1.4e-27 96.8 0.0 2.5e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KPA44231.1 - 2.5e-15 56.5 9.0 4.4e-15 55.7 9.0 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KPA44231.1 - 6.9e-05 22.1 10.1 6.9e-05 22.1 10.1 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KPA44231.1 - 0.00014 21.8 0.2 0.00027 20.9 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KPA44231.1 - 0.0049 16.9 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KPA44231.1 - 0.018 14.6 0.2 0.05 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KPA44231.1 - 0.025 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Dynamin family FtsK_SpoIIIE PF01580.18 KPA44231.1 - 0.041 13.2 0.0 0.57 9.5 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family IIGP PF05049.13 KPA44231.1 - 0.042 12.9 0.2 0.066 12.3 0.2 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) T2SSE PF00437.20 KPA44231.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KPA44231.1 - 0.075 12.8 0.5 0.18 11.6 0.5 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KPA44231.1 - 0.077 12.8 0.1 0.26 11.1 0.0 1.7 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 KPA44231.1 - 0.092 11.7 0.2 0.17 10.9 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KPA44231.1 - 0.097 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KPA44231.1 - 0.18 11.1 0.4 0.32 10.2 0.4 1.3 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 KPA44231.1 - 0.22 10.8 0.2 0.39 10.0 0.2 1.3 1 0 0 1 1 1 0 KaiC DUF87 PF01935.17 KPA44231.1 - 0.56 10.3 2.1 0.98 9.5 2.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain MOSC PF03473.17 KPA44232.1 - 2.2e-30 105.3 0.0 3.3e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KPA44232.1 - 5.2e-10 39.3 0.0 1.3e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain GLEYA PF10528.9 KPA44232.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 GLEYA domain His_Phos_2 PF00328.22 KPA44233.1 - 2.3e-113 379.4 0.0 7.4e-113 377.8 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KPA44233.1 - 2.3e-36 123.8 0.1 5.1e-36 122.7 0.1 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KPA44233.1 - 2.6e-05 23.9 0.0 5.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Sulfatase PF00884.23 KPA44234.1 - 8.8e-20 71.3 0.8 2e-19 70.1 0.8 1.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPA44234.1 - 5.1e-07 29.6 0.9 8e-07 29.0 0.9 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KPA44234.1 - 0.00087 18.0 0.0 0.0012 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Utp21 PF04192.12 KPA44235.1 - 4e-86 288.3 0.5 6e-86 287.7 0.5 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KPA44235.1 - 9.7e-19 67.4 15.2 5.2e-06 27.1 0.4 8.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA44235.1 - 4.2e-12 46.2 0.0 0.022 15.1 0.0 5.6 3 3 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA44235.1 - 4.7e-05 22.2 0.0 0.67 8.5 0.0 3.3 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KPA44235.1 - 0.00046 18.8 0.0 0.00099 17.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KPA44235.1 - 0.0027 16.5 0.0 2 7.0 0.0 2.4 1 1 1 2 2 2 2 Nup133 N terminal like COPI_assoc PF08507.10 KPA44236.1 - 5.1e-34 117.1 6.1 6e-34 116.9 6.1 1.0 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 KPA44236.1 - 0.0011 19.3 7.7 0.0018 18.6 7.7 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cytochrom_B558a PF05038.13 KPA44236.1 - 0.023 14.3 0.5 0.023 14.3 0.5 1.6 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DUF2754 PF10953.8 KPA44236.1 - 0.54 10.5 3.2 0.2 11.9 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) GTP_EFTU PF00009.27 KPA44237.1 - 4.5e-53 179.7 0.0 7.1e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KPA44237.1 - 2.1e-21 75.8 0.0 5e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KPA44237.1 - 1e-12 47.9 0.1 3.5e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KPA44237.1 - 0.0002 21.7 0.1 0.001 19.4 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KPA44237.1 - 0.00058 19.7 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Cupin_1 PF00190.22 KPA44238.1 - 4.9e-16 58.7 0.1 7.4e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KPA44238.1 - 0.061 13.0 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Cupin domain SUN PF03856.13 KPA44239.1 - 1.6e-76 257.0 11.5 3.2e-76 256.0 11.5 1.5 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Utp14 PF04615.13 KPA44239.1 - 2.1 6.8 14.9 2.7 6.5 14.9 1.1 1 0 0 1 1 1 0 Utp14 protein CCSAP PF15748.5 KPA44239.1 - 7.3 6.7 17.8 10 6.2 17.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PCI PF01399.27 KPA44240.1 - 4.5e-05 23.9 0.0 0.073 13.6 0.0 2.7 2 0 0 2 2 2 2 PCI domain Thiolase_N PF00108.23 KPA44241.1 - 1e-87 293.8 2.9 1.5e-87 293.3 2.9 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPA44241.1 - 3e-38 130.2 0.7 3e-38 130.2 0.7 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KPA44241.1 - 6.1e-05 22.7 0.9 0.00016 21.3 0.7 1.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KPA44241.1 - 2.2 8.2 5.3 9.2 6.2 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 KPA44242.1 - 1.6e-52 176.9 0.1 1.8e-52 176.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPA44242.1 - 0.00083 19.1 0.0 0.00092 18.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KPA44242.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.4 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.23 KPA44243.1 - 3.7e-112 374.5 0.1 1.2e-111 372.9 0.1 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPA44243.1 - 3.5e-26 91.9 0.0 1.4e-25 90.0 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding HAP1_N PF04849.13 KPA44243.1 - 1.9 7.6 54.3 0.036 13.3 20.0 4.1 3 1 1 4 4 4 0 HAP1 N-terminal conserved region HALZ PF02183.18 KPA44243.1 - 3.8 7.8 12.6 9.2 6.6 0.5 4.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper LCM PF04072.14 KPA44245.1 - 7.9e-20 71.6 0.0 2.2e-19 70.1 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase TFIID-18kDa PF02269.16 KPA44246.1 - 3.3e-17 62.3 7.8 7.7e-11 41.9 0.2 3.6 3 1 1 4 4 4 2 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.18 KPA44246.1 - 0.042 13.8 2.4 0.056 13.3 2.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region ArAE_2_N PF10337.9 KPA44247.1 - 4.5e-13 49.1 14.4 9.2e-09 34.8 0.0 3.3 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KPA44247.1 - 8.3e-12 45.3 16.4 8.3e-12 45.3 16.4 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KPA44247.1 - 1.6e-05 24.0 12.5 1.6e-05 24.0 12.5 2.5 2 0 0 2 2 2 1 Aluminium activated malate transporter ArAE_2 PF10334.9 KPA44247.1 - 0.00059 19.7 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 PDCD7 PF16021.5 KPA44247.1 - 2.1 7.4 6.9 0.39 9.8 2.9 1.7 2 0 0 2 2 2 0 Programmed cell death protein 7 Clat_adaptor_s PF01217.20 KPA44248.1 - 5.6e-56 188.4 1.5 6.2e-56 188.3 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ist1 PF03398.14 KPA44249.1 - 6.1e-61 205.1 1.6 7.8e-61 204.8 1.6 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway PDZ_1 PF12812.7 KPA44250.1 - 5.8e-55 183.2 0.1 1.3e-36 124.5 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KPA44250.1 - 2.4e-22 80.4 0.5 5.1e-19 69.6 0.1 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 KPA44250.1 - 2.4e-13 50.2 0.1 6.2e-06 26.4 0.0 4.4 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 KPA44250.1 - 5.6e-13 48.5 0.1 0.00019 21.2 0.1 4.1 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 KPA44250.1 - 8.7e-09 35.6 0.0 0.00012 22.4 0.0 3.6 3 0 0 3 3 3 1 PDZ domain 4HPAD_g_N PF18671.1 KPA44250.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Tricorn_PDZ PF14685.6 KPA44250.1 - 0.011 15.7 0.1 0.82 9.7 0.1 3.3 3 0 0 3 3 3 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 KPA44250.1 - 0.016 13.9 0.4 0.038 12.6 0.1 1.6 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S7 PF00949.21 KPA44250.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 KPA44250.1 - 0.25 10.8 0.1 0.42 10.1 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) FPN1 PF06963.12 KPA44251.1 - 2e-44 151.9 1.9 2.4e-44 151.6 1.9 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Anillin_N PF16018.5 KPA44252.1 - 0.018 15.7 0.5 0.034 14.7 0.4 1.7 1 1 0 1 1 1 0 Anillin N-terminus Myb_DNA-binding PF00249.31 KPA44252.1 - 0.029 14.6 0.2 0.081 13.1 0.2 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain DnaJ PF00226.31 KPA44253.1 - 2.8e-21 75.4 1.5 7.2e-21 74.1 1.5 1.8 1 0 0 1 1 1 1 DnaJ domain CUE PF02845.16 KPA44254.1 - 1.3e-10 40.7 0.0 2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain VIR_N PF15912.5 KPA44254.1 - 0.033 13.8 2.3 0.042 13.5 1.4 1.6 2 0 0 2 2 2 0 Virilizer, N-terminal Cue1_U7BR PF18499.1 KPA44254.1 - 0.12 12.4 3.5 0.23 11.5 3.5 1.6 1 1 0 1 1 1 0 Ubc7p-binding region of Cue1 NOT2_3_5 PF04153.18 KPA44255.1 - 4e-28 98.1 1.1 6.6e-28 97.4 1.1 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family cobW PF02492.19 KPA44256.1 - 5.5e-48 162.9 0.4 7.1e-48 162.5 0.4 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KPA44256.1 - 1e-05 25.5 0.4 0.19 11.6 0.0 2.5 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KPA44256.1 - 0.00035 20.2 0.1 0.17 11.4 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 KPA44256.1 - 0.0013 19.3 0.5 0.003 18.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPA44256.1 - 0.0013 18.5 0.2 0.28 10.9 0.1 2.2 2 0 0 2 2 2 2 AAA domain Septin PF00735.18 KPA44256.1 - 0.004 16.5 1.8 0.43 9.8 0.2 2.4 2 1 0 2 2 2 2 Septin MeaB PF03308.16 KPA44256.1 - 0.0051 15.8 1.4 2.6 6.9 0.1 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KPA44256.1 - 0.0085 16.2 0.0 0.021 14.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KPA44256.1 - 0.012 15.9 0.1 0.33 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KPA44256.1 - 0.017 14.9 0.9 0.098 12.4 0.9 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KPA44256.1 - 0.021 15.2 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KPA44256.1 - 0.023 14.4 0.4 0.07 12.9 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 KPA44256.1 - 0.034 14.2 0.1 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KPA44256.1 - 0.44 9.6 3.2 0.18 10.8 0.3 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Mob1_phocein PF03637.17 KPA44257.1 - 2.3e-22 79.8 0.2 3.4e-22 79.3 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 KPA44257.1 - 0.15 12.3 4.4 0.36 11.1 4.4 1.6 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Fungal_trans_2 PF11951.8 KPA44258.1 - 3.4e-12 45.9 0.1 1.9e-11 43.4 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA44258.1 - 2.3e-07 30.8 10.8 5.1e-07 29.7 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 KPA44258.1 - 1.6 9.2 4.0 4.1 7.8 4.0 1.7 1 0 0 1 1 1 0 Opy2 protein SMC_N PF02463.19 KPA44260.1 - 2e-70 236.7 0.0 1.9e-69 233.4 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KPA44260.1 - 1.8e-22 79.8 2.7 3.5e-22 78.9 0.5 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KPA44260.1 - 3.3e-10 40.2 7.0 0.00019 21.3 0.1 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPA44260.1 - 0.00011 21.8 0.1 0.00033 20.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.7 KPA44260.1 - 0.00019 21.1 15.5 0.00019 21.1 15.5 6.6 3 3 3 7 7 7 4 Mechanosensitive ion channel porin domain HSBP1 PF06825.12 KPA44260.1 - 0.047 13.5 13.5 0.15 11.9 0.2 4.2 4 0 0 4 4 4 0 Heat shock factor binding protein 1 ABC_tran PF00005.27 KPA44260.1 - 0.11 13.1 0.0 0.11 13.1 0.0 5.9 3 2 0 3 3 3 0 ABC transporter FDX-ACB PF03147.14 KPA44260.1 - 0.13 12.7 6.0 0.5 10.8 0.6 3.8 3 0 0 3 3 3 0 Ferredoxin-fold anticodon binding domain INCENP_ARK-bind PF03941.15 KPA44261.1 - 7.2e-18 64.3 0.9 7.2e-18 64.3 0.9 3.7 5 0 0 5 5 5 1 Inner centromere protein, ARK binding region DUF2267 PF10025.9 KPA44262.1 - 0.11 12.8 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DEAD PF00270.29 KPA44263.1 - 1.8e-44 151.6 0.1 2.9e-44 150.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA44263.1 - 4e-21 75.4 0.0 3e-20 72.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KPA44263.1 - 0.0022 17.3 0.1 0.0035 16.6 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KPA44263.1 - 0.0027 17.7 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ImcF-related_N PF14331.6 KPA44263.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 ImcF-related N-terminal domain AAA_22 PF13401.6 KPA44263.1 - 0.044 14.0 0.1 0.26 11.6 0.2 2.2 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 KPA44264.1 - 6.6e-17 61.6 11.1 0.00052 20.8 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA44264.1 - 0.0016 18.7 0.1 1.6 9.1 0.0 3.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Rav1p_C PF12234.8 KPA44264.1 - 0.15 10.4 0.0 0.32 9.4 0.0 1.4 2 0 0 2 2 2 0 RAVE protein 1 C terminal 2OG-FeII_Oxy_2 PF13532.6 KPA44265.1 - 1.6e-35 123.1 0.3 2.8e-35 122.3 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KPA44265.1 - 8.4e-09 35.4 6.7 1.6e-08 34.5 6.7 1.5 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 KPA44265.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 CUE domain RibD_C PF01872.17 KPA44266.1 - 1e-32 113.6 0.0 1.2e-32 113.4 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Transp_cyt_pur PF02133.15 KPA44267.1 - 5.1e-26 91.4 27.9 3.7e-25 88.6 27.8 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin p450 PF00067.22 KPA44268.1 - 1.5e-30 106.4 0.0 2.2e-16 59.6 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Glyco_hydro_3_C PF01915.22 KPA44269.1 - 7e-61 205.7 0.0 1.1e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPA44269.1 - 1.2e-41 143.1 0.0 2.4e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPA44269.1 - 5.5e-25 87.3 0.4 3.2e-24 84.8 0.1 2.4 3 0 0 3 3 3 1 Fibronectin type III-like domain PA14 PF07691.12 KPA44269.1 - 8.2e-17 61.4 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Lipase_GDSL_2 PF13472.6 KPA44269.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family FAD_binding_4 PF01565.23 KPA44270.1 - 4.2e-33 114.0 3.3 4.2e-33 114.0 3.3 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KPA44270.1 - 4.9e-10 39.4 0.0 9.3e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans_2 PF11951.8 KPA44271.1 - 4.6e-11 42.1 0.9 4.6e-11 42.1 0.9 2.0 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA44271.1 - 2.5e-05 24.3 11.9 5.9e-05 23.1 11.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Patatin PF01734.22 KPA44272.1 - 1.8e-15 57.6 0.0 9.2e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Raptor_N PF14538.6 KPA44273.1 - 0.00085 19.3 0.1 0.0022 18.0 0.0 1.7 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain zf-C2H2 PF00096.26 KPA44273.1 - 0.0009 19.6 18.0 0.06 13.8 2.0 4.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type Peptidase_C14 PF00656.22 KPA44273.1 - 0.009 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Caspase domain zf-TRAF PF02176.18 KPA44273.1 - 0.056 14.2 0.9 0.19 12.4 0.9 2.0 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_4 PF13894.6 KPA44273.1 - 0.12 13.3 21.8 0.15 13.0 1.9 5.1 4 1 0 4 4 4 0 C2H2-type zinc finger Sina PF03145.16 KPA44273.1 - 0.3 11.0 4.0 0.54 10.2 4.0 1.4 1 0 0 1 1 1 0 Seven in absentia protein family Rft-1 PF04506.13 KPA44274.1 - 3.7e-152 507.7 12.5 4.2e-152 507.5 12.5 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 KPA44274.1 - 4.2e-11 42.7 15.2 4.2e-11 42.7 15.2 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 KPA44274.1 - 1.2 8.3 17.1 0.071 12.3 7.4 3.4 1 1 2 3 3 3 0 Polysaccharide biosynthesis protein DEAD PF00270.29 KPA44275.1 - 2e-49 167.8 0.0 4.9e-49 166.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA44275.1 - 2.7e-34 117.8 0.0 2.8e-30 104.9 0.1 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 KPA44275.1 - 0.00087 18.2 0.0 0.0066 15.3 0.0 2.3 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 TFIIF_alpha PF05793.12 KPA44275.1 - 0.98 7.9 28.9 1.4 7.4 28.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAGA-Tad1 PF12767.7 KPA44275.1 - 1.2 8.8 14.3 2 8.1 14.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Mucin15 PF15672.5 KPA44275.1 - 2.8 7.4 12.2 5.1 6.5 12.2 1.4 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 SOBP PF15279.6 KPA44275.1 - 8 7.0 13.4 12 6.4 13.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.10 KPA44275.1 - 9.5 4.8 12.2 11 4.5 12.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HORMA PF02301.18 KPA44276.1 - 2.6e-32 112.2 0.0 3.2e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KPA44276.1 - 0.01 15.8 0.3 0.034 14.1 0.3 1.9 1 1 0 1 1 1 0 Autophagy-related protein 101 DUF2660 PF10859.8 KPA44276.1 - 0.032 14.7 0.1 0.078 13.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF4760 PF15956.5 KPA44276.1 - 0.099 12.8 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) UCH PF00443.29 KPA44277.1 - 1.6e-37 129.4 0.0 2.5e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KPA44277.1 - 5.5e-24 84.3 10.9 2.8e-19 69.2 1.5 3.0 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KPA44277.1 - 1.3e-23 82.5 0.9 2.9e-22 78.2 0.1 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 KPA44277.1 - 1.2e-20 73.0 0.1 5.5e-10 39.0 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KPA44277.1 - 4.2e-15 56.1 0.0 1.1e-13 51.5 0.0 2.9 2 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Sugar_tr PF00083.24 KPA44278.1 - 3.6e-119 398.6 22.1 4.2e-119 398.4 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA44278.1 - 1.3e-16 60.5 51.6 1.6e-14 53.6 25.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_14 PF13428.6 KPA44278.1 - 0.028 15.2 0.4 0.058 14.2 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KPA44278.1 - 0.11 13.0 0.2 0.23 12.0 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Met_10 PF02475.16 KPA44280.1 - 0.24 11.1 0.0 2.2 8.0 0.0 2.0 2 0 0 2 2 2 0 Met-10+ like-protein DUF4386 PF14329.6 KPA44280.1 - 2.8 7.8 9.0 0.87 9.4 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4386) Helo_like_N PF17111.5 KPA44281.1 - 0.0019 17.6 0.3 0.0045 16.4 0.3 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Peptidase_C2 PF00648.21 KPA44282.1 - 1.6e-61 207.9 0.3 5.5e-60 202.9 0.3 2.5 1 1 0 1 1 1 1 Calpain family cysteine protease EF-hand_7 PF13499.6 KPA44282.1 - 0.36 11.3 2.2 11 6.6 0.0 4.0 4 0 0 4 4 4 0 EF-hand domain pair ATP11 PF06644.11 KPA44282.1 - 0.44 10.3 0.0 0.44 10.3 0.0 3.2 2 1 0 2 2 2 0 ATP11 protein zf-CCHC PF00098.23 KPA44283.1 - 3.5e-45 150.1 60.8 6e-08 32.4 2.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KPA44283.1 - 6.7e-10 38.5 39.0 0.16 11.7 1.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KPA44283.1 - 0.00019 21.3 43.7 0.073 13.1 0.3 6.9 3 2 3 6 6 6 4 Zinc knuckle zf-CCHC_5 PF14787.6 KPA44283.1 - 0.00049 19.8 45.2 0.0073 16.0 1.0 7.1 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KPA44283.1 - 0.061 13.2 2.0 0.061 13.2 2.0 7.2 7 0 0 7 7 7 0 Zinc knuckle WD40 PF00400.32 KPA44285.1 - 6e-38 128.2 4.0 6.8e-07 29.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA44285.1 - 8.4e-13 48.4 0.1 0.0015 18.8 0.0 4.6 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KPA44285.1 - 0.0026 16.6 1.8 1.5 7.5 0.1 3.4 1 1 1 3 3 3 2 Nup133 N terminal like WD40_like PF17005.5 KPA44285.1 - 0.031 13.6 0.0 1.3 8.3 0.0 2.6 1 1 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 KPA44285.1 - 0.062 11.9 0.1 15 4.1 0.0 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KPA44285.1 - 0.066 12.2 0.0 27 3.6 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TRAPP PF04051.16 KPA44286.1 - 3.4e-37 127.4 0.1 4.1e-37 127.1 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.6 KPA44286.1 - 0.036 14.0 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Ribosomal_L32p PF01783.23 KPA44287.1 - 0.11 12.7 3.7 0.24 11.7 3.7 1.6 1 0 0 1 1 1 0 Ribosomal L32p protein family LisH PF08513.11 KPA44287.1 - 0.14 12.1 0.3 0.3 11.1 0.3 1.4 1 0 0 1 1 1 0 LisH Glyco_hydro_16 PF00722.21 KPA44288.1 - 1.6e-18 66.8 0.4 2.2e-18 66.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KPA44288.1 - 2e-11 43.0 2.8 2.8e-05 22.7 0.9 2.0 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 KPA44288.1 - 0.037 13.6 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) TFB6 PF17110.5 KPA44289.1 - 1.2e-63 213.9 0.0 1.5e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH SDA1 PF05285.12 KPA44289.1 - 0.12 11.8 1.5 0.15 11.4 1.5 1.1 1 0 0 1 1 1 0 SDA1 STE2 PF02116.15 KPA44291.1 - 2e-91 306.2 25.5 2.3e-91 306.0 25.5 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR UEV PF05743.13 KPA44292.1 - 1.3e-36 125.1 0.0 1.9e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KPA44292.1 - 2.3e-21 75.5 0.0 5.2e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Vps23 core domain IDO PF01231.18 KPA44293.1 - 1e-169 564.9 0.0 1.2e-169 564.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KPA44293.1 - 0.16 10.7 0.0 6.1 5.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Glyco_hydro_45 PF02015.16 KPA44294.1 - 1.4e-100 335.5 16.5 2.3e-100 334.8 16.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CBM_1 PF00734.18 KPA44294.1 - 1e-08 35.0 1.7 1e-08 35.0 1.7 3.6 3 0 0 3 3 3 1 Fungal cellulose binding domain RNA_pol_Rpb2_6 PF00562.28 KPA44295.1 - 2.6e-126 421.8 0.3 6.1e-126 420.6 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KPA44295.1 - 1.7e-54 184.4 0.0 6.1e-54 182.6 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KPA44295.1 - 8.8e-46 155.9 0.0 2.2e-45 154.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KPA44295.1 - 1.4e-32 111.9 0.1 3.4e-32 110.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KPA44295.1 - 2e-25 88.7 0.1 5e-25 87.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KPA44295.1 - 2.3e-21 76.1 11.2 1e-20 74.0 11.2 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 KPA44295.1 - 1.6e-19 69.9 1.6 5e-19 68.4 0.2 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_45 PF10385.9 KPA44295.1 - 0.49 10.7 3.1 4.5 7.6 0.3 3.1 3 0 0 3 3 3 0 RNA polymerase beta subunit external 1 domain MRNIP PF15749.5 KPA44295.1 - 0.87 10.3 5.5 3.3 8.5 0.1 2.7 2 0 0 2 2 2 0 MRN-interacting protein PET117 PF15786.5 KPA44296.1 - 1e-25 89.8 3.5 1.2e-25 89.5 3.5 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial V-ATPase_G PF03179.15 KPA44297.1 - 1.2e-30 106.1 16.5 1.4e-30 105.9 16.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 KPA44297.1 - 0.011 16.1 16.4 0.014 15.8 16.4 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 KPA44297.1 - 0.033 13.6 20.3 0.019 14.4 16.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ATP11 PF06644.11 KPA44297.1 - 0.15 11.8 8.9 0.17 11.7 8.9 1.0 1 0 0 1 1 1 0 ATP11 protein CENP-H PF05837.12 KPA44297.1 - 0.73 10.3 7.5 0.97 9.9 7.5 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HAUS6_N PF14661.6 KPA44297.1 - 0.98 8.9 9.4 1.2 8.7 9.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ATP-synt_B PF00430.18 KPA44297.1 - 0.99 9.5 22.6 0.22 11.6 11.8 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) RRF PF01765.19 KPA44297.1 - 3.9 7.4 12.6 5.3 7.0 12.6 1.2 1 0 0 1 1 1 0 Ribosome recycling factor MRP-S26 PF14943.6 KPA44297.1 - 8.7 6.2 17.9 0.59 10.0 8.8 2.0 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 CTNNBL PF08216.11 KPA44298.1 - 4.9e-41 139.1 0.2 2e-40 137.2 0.0 2.2 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KPA44298.1 - 0.003 17.5 0.1 3.3 7.9 0.0 4.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Mo25 PF08569.11 KPA44298.1 - 0.02 14.3 0.8 0.025 14.0 0.1 1.6 2 0 0 2 2 2 0 Mo25-like Arm_3 PF16186.5 KPA44298.1 - 0.088 12.4 0.2 25 4.5 0.0 3.1 2 0 0 2 2 2 0 Atypical Arm repeat MIT PF04212.18 KPA44299.1 - 1.8e-14 53.5 1.8 3.7e-14 52.5 1.8 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Wbp11 PF09429.10 KPA44299.1 - 1.7 9.1 4.4 2.3 8.7 0.0 3.2 3 0 0 3 3 3 0 WW domain binding protein 11 GTP_EFTU PF00009.27 KPA44300.1 - 2.7e-50 170.6 0.0 4.1e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KPA44300.1 - 8.1e-42 141.7 2.6 1.3e-41 141.0 2.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KPA44300.1 - 1.4e-20 73.1 0.0 2.7e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KPA44300.1 - 1.9e-06 28.2 0.1 4.1e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KPA44300.1 - 2.5e-05 24.3 0.1 7.1e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.6 KPA44300.1 - 0.00025 21.1 0.0 0.00069 19.7 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 KPA44300.1 - 0.0012 18.5 0.0 0.0032 17.1 0.0 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KPA44300.1 - 0.02 15.1 0.1 0.29 11.4 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KPA44300.1 - 0.023 14.2 0.0 0.07 12.6 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RF3_C PF16658.5 KPA44300.1 - 0.036 13.9 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain Snurportin1 PF11538.8 KPA44300.1 - 0.42 10.8 2.5 0.92 9.7 2.5 1.5 1 0 0 1 1 1 0 Snurportin1 His_Phos_1 PF00300.22 KPA44301.1 - 2.3e-10 40.5 0.0 3.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cutinase PF01083.22 KPA44302.1 - 1e-28 100.5 0.2 1e-28 100.5 0.2 1.8 2 0 0 2 2 2 1 Cutinase PE-PPE PF08237.11 KPA44302.1 - 0.00063 19.4 1.4 0.019 14.5 0.0 2.3 2 0 0 2 2 2 1 PE-PPE domain DUF2235 PF09994.9 KPA44303.1 - 1e-85 287.6 2.1 9.3e-85 284.5 2.1 2.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Helo_like_N PF17111.5 KPA44305.1 - 1.8e-07 30.8 0.1 1.8e-07 30.8 0.1 1.4 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KPA44305.1 - 4.9e-05 23.5 0.2 0.00012 22.3 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 KPA44305.1 - 0.00027 20.9 0.1 0.0015 18.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KPA44305.1 - 0.035 14.4 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KPA44305.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran_CTD PF16326.5 KPA44305.1 - 0.059 13.6 0.5 0.65 10.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain AAA_11 PF13086.6 KPA44305.1 - 0.11 12.3 0.0 0.61 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain BLOC1S3 PF15753.5 KPA44305.1 - 0.12 12.6 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 MscS_porin PF12795.7 KPA44305.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain AAA_30 PF13604.6 KPA44305.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.12 KPA44305.1 - 0.22 11.6 0.6 0.47 10.5 0.1 1.7 2 0 0 2 2 2 0 Laminin Domain II DUF4200 PF13863.6 KPA44305.1 - 0.28 11.6 0.9 2.1 8.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) F-box-like PF12937.7 KPA44306.1 - 0.00015 21.6 0.3 0.00041 20.2 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KPA44306.1 - 0.00019 21.2 0.2 0.00045 20.0 0.2 1.7 1 0 0 1 1 1 1 F-box domain MAGE_N PF12440.8 KPA44307.1 - 0.16 12.7 6.3 0.41 11.4 6.3 1.7 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Ank_3 PF13606.6 KPA44308.1 - 5.7e-14 50.9 0.0 0.35 11.6 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_2 PF12796.7 KPA44308.1 - 7.8e-12 45.6 0.0 0.00057 20.4 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA44308.1 - 1.5e-11 44.6 0.0 0.0092 16.5 0.0 6.2 4 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA44308.1 - 7.1e-10 39.0 0.0 0.042 14.2 0.0 4.5 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KPA44308.1 - 8.9e-07 29.1 0.1 3 8.5 0.0 5.6 6 1 0 6 6 6 1 Ankyrin repeat MU117 PF15474.6 KPA44309.1 - 1.8e-20 73.6 9.1 4.4e-20 72.4 9.1 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene family Na_trans_assoc PF06512.13 KPA44309.1 - 0.06 13.6 13.3 0.013 15.8 7.4 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated BUD22 PF09073.10 KPA44309.1 - 0.083 12.2 15.8 0.33 10.2 7.2 2.3 2 0 0 2 2 2 0 BUD22 ATP-grasp_6 PF18419.1 KPA44311.1 - 0.031 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp-like domain KaiA PF07688.12 KPA44311.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiA C-terminal domain AA_permease PF00324.21 KPA44313.1 - 1.5e-84 284.3 32.6 1.8e-84 284.1 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA44313.1 - 4.4e-21 75.2 37.3 5.6e-21 74.9 37.3 1.1 1 0 0 1 1 1 1 Amino acid permease zf-U1 PF06220.12 KPA44314.1 - 7.6e-08 32.0 0.5 1.2e-07 31.4 0.5 1.3 1 0 0 1 1 1 1 U1 zinc finger FMN_bind PF04205.14 KPA44314.1 - 0.063 13.9 0.0 0.27 11.9 0.0 1.9 2 0 0 2 2 2 0 FMN-binding domain DLH PF01738.18 KPA44315.1 - 2.1e-30 105.9 0.2 2.4e-30 105.7 0.2 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KPA44315.1 - 0.076 12.9 0.1 6.6 6.6 0.0 2.3 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF747 PF05346.11 KPA44316.1 - 1.4e-119 399.3 7.2 1.8e-119 399.0 7.2 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Roughex PF06020.11 KPA44316.1 - 0.14 11.2 8.2 0.23 10.5 8.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Macoilin PF09726.9 KPA44316.1 - 3.8 6.0 6.0 6.1 5.3 6.0 1.2 1 0 0 1 1 1 0 Macoilin family HemY_N PF07219.13 KPA44316.1 - 9.2 6.5 5.8 0.92 9.7 0.6 2.0 2 0 0 2 2 2 0 HemY protein N-terminus HEAT_EZ PF13513.6 KPA44317.1 - 4.4e-19 68.6 2.9 2.3e-07 31.1 0.2 7.4 5 2 3 8 8 7 4 HEAT-like repeat HEAT PF02985.22 KPA44317.1 - 8.7e-17 59.8 2.8 0.054 13.8 0.1 8.9 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 KPA44317.1 - 6.4e-15 55.3 6.4 0.022 15.1 0.1 7.4 4 2 3 7 7 7 5 HEAT repeats Cnd1 PF12717.7 KPA44317.1 - 2.9e-08 33.9 0.0 0.49 10.4 0.0 4.9 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KPA44317.1 - 5.9e-08 33.2 0.0 0.076 13.6 0.0 5.0 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KPA44317.1 - 6.3e-08 31.6 0.1 0.0074 14.9 0.0 4.3 4 1 0 4 4 4 2 Adaptin N terminal region Arm PF00514.23 KPA44317.1 - 3.8e-07 29.9 0.1 0.09 12.9 0.0 6.3 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 KPA44317.1 - 1.8e-06 27.8 0.0 0.054 13.2 0.0 3.8 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 KPA44317.1 - 1.3e-05 24.9 0.0 1.5 8.3 0.0 4.1 4 0 0 4 4 4 2 CLASP N terminal IFRD PF05004.13 KPA44317.1 - 1.3e-05 24.5 0.7 0.37 9.8 0.1 4.2 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) IBN_N PF03810.19 KPA44317.1 - 0.00026 20.8 0.1 0.0015 18.4 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain MMS19_C PF12460.8 KPA44317.1 - 0.0057 15.8 2.0 0.22 10.6 0.1 3.4 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KPA44317.1 - 0.025 14.5 0.2 30 4.5 0.0 4.9 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) Tti2 PF10521.9 KPA44317.1 - 0.034 13.7 0.0 1 8.8 0.0 3.3 4 0 0 4 4 4 0 Tti2 family RTP1_C1 PF10363.9 KPA44317.1 - 0.098 12.9 0.4 2.3 8.4 0.1 3.4 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 LysM PF01476.20 KPA44318.1 - 5.6e-11 42.3 0.0 9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 LysM domain LPD28 PF18843.1 KPA44318.1 - 0.14 11.8 0.1 0.87 9.3 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 28 LacI PF00356.21 KPA44318.1 - 0.14 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family SSXT PF05030.12 KPA44319.1 - 0.15 11.7 0.2 0.37 10.4 0.2 1.6 1 0 0 1 1 1 0 SSXT protein (N-terminal region) WD40 PF00400.32 KPA44320.1 - 1.2e-41 139.8 12.2 1.4e-05 25.8 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KPA44320.1 - 4.6e-09 36.0 0.1 9.6e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA44320.1 - 7.6e-09 35.2 0.1 2e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KPA44320.1 - 1.6e-07 31.5 0.6 1.1 9.6 0.0 5.4 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KPA44320.1 - 0.0059 16.2 0.3 0.22 11.1 0.3 2.7 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.8 KPA44320.1 - 0.31 9.6 10.3 32 3.0 0.0 5.6 3 2 3 6 6 6 0 Nucleoporin Nup120/160 Lar_restr_allev PF14354.6 KPA44321.1 - 4.2 7.8 10.3 11 6.5 0.1 4.5 4 0 0 4 4 4 0 Restriction alleviation protein Lar ANAPC4_WD40 PF12894.7 KPA44322.1 - 6e-06 26.5 0.0 0.27 11.6 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPA44322.1 - 1.2e-05 26.0 7.2 0.071 14.0 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KPA44322.1 - 0.028 13.4 0.1 2.8 6.8 0.0 3.1 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DAZAP2 PF11029.8 KPA44322.1 - 0.096 13.6 0.2 0.23 12.4 0.1 1.7 1 1 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) RalF_SCD PF18248.1 KPA44322.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 RalF C-terminal Sec-7 capping domain Peptidase_M20 PF01546.28 KPA44326.1 - 7.4e-22 78.1 0.0 3.9e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KPA44326.1 - 6.9e-16 58.4 7.2 0.0037 18.1 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Peptidase_M28 PF04389.17 KPA44326.1 - 4.5e-05 23.2 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 KPA44326.1 - 0.0012 18.8 0.0 0.0029 17.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.8 KPA44326.1 - 0.0032 16.2 0.4 4.7 5.7 0.0 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KPA44326.1 - 0.01 14.8 0.2 0.028 13.4 0.1 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Podoplanin PF05808.11 KPA44327.1 - 0.013 15.7 2.9 0.021 14.9 2.9 1.3 1 0 0 1 1 1 0 Podoplanin DUF4328 PF14219.6 KPA44327.1 - 0.041 13.5 0.1 0.073 12.6 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4328) Sporozoite_P67 PF05642.11 KPA44327.1 - 0.061 11.4 6.3 0.12 10.5 6.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SKG6 PF08693.10 KPA44327.1 - 0.086 12.3 0.7 0.17 11.4 0.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FAM199X PF15814.5 KPA44327.1 - 1.6 7.7 7.7 2.3 7.2 7.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X FSA_C PF10479.9 KPA44327.1 - 3 5.9 10.9 4.9 5.2 10.9 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus HET PF06985.11 KPA44328.1 - 6.6e-20 72.0 0.0 1.2e-19 71.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 KPA44329.1 - 1.2e-41 142.4 0.0 1.8e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA44329.1 - 1.9e-29 102.9 0.0 2.4e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KPA44329.1 - 0.00082 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 KPA44329.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 KPA44329.1 - 0.2 10.7 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Zip PF02535.22 KPA44330.1 - 2.2e-36 125.7 39.8 4.8e-18 65.5 4.9 3.7 3 1 1 4 4 4 3 ZIP Zinc transporter Fer4_13 PF13370.6 KPA44330.1 - 3.1 8.4 5.3 7.4 7.2 0.2 3.1 1 1 2 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Zip PF02535.22 KPA44331.1 - 0.052 12.8 5.9 0.065 12.4 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RHIM PF12721.7 KPA44331.1 - 8.4 7.0 8.1 13 6.4 0.9 3.2 3 0 0 3 3 3 0 RIP homotypic interaction motif Selenoprotein_S PF06936.11 KPA44332.1 - 0.012 15.4 2.5 0.023 14.5 2.5 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) TFIIA PF03153.13 KPA44332.1 - 1.5 8.7 6.3 1.7 8.5 6.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 KPA44332.1 - 6.6 6.0 8.6 1.5 8.1 1.8 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein ECH_1 PF00378.20 KPA44333.1 - 9.5e-47 159.4 0.0 1.2e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA44333.1 - 6.3e-21 75.2 0.1 1.2e-19 71.0 0.1 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Clr5 PF14420.6 KPA44334.1 - 7.3e-21 74.2 5.0 7.8e-21 74.1 0.9 2.7 3 0 0 3 3 3 1 Clr5 domain SCIMP PF15050.6 KPA44334.1 - 0.18 12.3 1.0 0.47 10.9 1.0 1.7 1 0 0 1 1 1 0 SCIMP protein NINJA_B PF16136.5 KPA44334.1 - 0.53 10.7 4.5 0.31 11.4 1.5 2.1 2 0 0 2 2 2 0 Putative nuclear localisation signal FAD-oxidase_C PF02913.19 KPA44335.1 - 6.7e-62 209.4 2.4 8e-62 209.1 0.3 1.9 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KPA44335.1 - 8.3e-36 122.8 0.0 1.6e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain UPF0183 PF03676.14 KPA44336.1 - 5.8e-59 200.3 0.0 5.1e-35 121.5 0.0 3.1 2 1 1 3 3 3 3 Uncharacterised protein family (UPF0183) LRR_RI_capping PF18779.1 KPA44336.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat Amidase PF01425.21 KPA44337.1 - 7.9e-59 199.8 0.0 1.3e-58 199.0 0.0 1.3 1 0 0 1 1 1 1 Amidase GATA PF00320.27 KPA44339.1 - 1.3e-15 56.7 5.7 2.4e-15 55.8 5.7 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KPA44339.1 - 2.4e-12 46.9 0.0 4.7e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KPA44339.1 - 5.2e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KPA44339.1 - 0.002 18.4 0.2 0.0066 16.7 0.0 1.9 2 0 0 2 2 2 1 PAS domain Zn-ribbon_8 PF09723.10 KPA44339.1 - 0.0042 17.2 0.2 0.0087 16.2 0.2 1.5 1 0 0 1 1 1 1 Zinc ribbon domain PAS_4 PF08448.10 KPA44339.1 - 0.0056 16.9 0.0 0.014 15.6 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KPA44339.1 - 0.02 15.0 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 PAS domain TF_Zn_Ribbon PF08271.12 KPA44339.1 - 0.088 12.3 0.5 0.73 9.4 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF2263 PF10021.9 KPA44339.1 - 0.14 12.5 0.2 0.33 11.3 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2263) DUF4428 PF14471.6 KPA44339.1 - 2.8 8.0 4.9 0.91 9.5 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) AAA_23 PF13476.6 KPA44340.1 - 6.3e-33 115.0 5.8 6.3e-33 115.0 5.8 7.4 1 1 1 3 3 1 1 AAA domain AAA_21 PF13304.6 KPA44340.1 - 8.8e-10 38.9 7.3 0.00077 19.4 1.6 4.3 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KPA44340.1 - 7.8e-07 29.2 0.0 1.4e-05 25.2 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KPA44340.1 - 0.0011 18.8 5.0 0.0011 18.8 5.0 5.7 1 1 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 KPA44340.1 - 0.0024 17.6 0.0 0.0065 16.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KPA44340.1 - 0.051 14.0 0.0 0.051 14.0 0.0 5.3 4 2 0 5 5 5 0 AAA ATPase domain ABC_tran PF00005.27 KPA44340.1 - 0.077 13.5 0.0 0.077 13.5 0.0 7.7 4 1 1 5 5 4 0 ABC transporter AAA_33 PF13671.6 KPA44340.1 - 0.14 12.3 0.0 0.14 12.3 0.0 4.0 4 1 0 4 4 3 0 AAA domain AAA_22 PF13401.6 KPA44340.1 - 0.23 11.7 5.1 0.28 11.4 0.1 3.8 2 1 1 3 3 3 0 AAA domain AAA_13 PF13166.6 KPA44340.1 - 0.32 9.6 114.2 0.19 10.4 0.1 6.7 2 1 4 6 6 5 0 AAA domain Methyltransf_25 PF13649.6 KPA44340.1 - 0.75 10.5 2.6 5.5 7.8 0.1 3.8 3 0 0 3 3 3 0 Methyltransferase domain MFS_1 PF07690.16 KPA44341.1 - 8.4e-50 169.7 55.5 8.4e-50 169.7 55.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA44341.1 - 3.1e-23 82.0 22.2 8.4e-23 80.6 22.1 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPA44341.1 - 1.7e-12 47.0 16.2 1.7e-12 47.0 16.2 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KPA44341.1 - 0.17 10.2 13.0 0.67 8.2 4.6 3.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family OAD_gamma PF04277.13 KPA44341.1 - 0.95 10.1 0.0 0.95 10.1 0.0 2.8 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain FMO-like PF00743.19 KPA44342.1 - 1.7e-41 142.3 0.0 3.5e-24 85.1 0.2 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPA44342.1 - 7e-15 55.1 0.8 1.9e-09 37.2 0.2 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA44342.1 - 7.9e-14 51.6 0.0 2.4e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA44342.1 - 1.7e-10 41.1 0.0 3.2e-09 37.0 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KPA44342.1 - 2.7e-10 40.4 0.0 0.0064 16.1 0.0 3.4 2 1 0 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 KPA44342.1 - 7.7e-10 38.4 0.0 3.9e-06 26.2 0.0 3.0 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPA44342.1 - 4.8e-07 29.9 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPA44342.1 - 1.2e-06 27.9 0.0 2.1e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KPA44342.1 - 4.4e-05 24.0 0.3 0.28 11.7 0.0 3.4 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA44342.1 - 0.0055 15.5 0.4 0.025 13.3 0.1 2.2 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.20 KPA44342.1 - 0.013 15.6 0.0 0.92 9.6 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 KPA44342.1 - 0.02 14.2 0.0 0.77 9.0 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase MCRA PF06100.11 KPA44342.1 - 0.02 13.7 0.0 0.05 12.4 0.0 1.6 2 0 0 2 2 2 0 MCRA family FAD_binding_3 PF01494.19 KPA44342.1 - 0.18 11.0 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Fungal_trans PF04082.18 KPA44343.1 - 8.4e-21 74.2 0.0 1.2e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA44343.1 - 3.1e-07 30.4 8.0 4.9e-07 29.8 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SEF14_adhesin PF06443.11 KPA44343.1 - 0.067 13.1 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 SEF14-like adhesin DUF3523 PF12037.8 KPA44343.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Opy2 PF09463.10 KPA44343.1 - 9.5 6.6 7.8 25 5.3 7.6 1.7 1 1 1 2 2 2 0 Opy2 protein DUF2339 PF10101.9 KPA44344.1 - 0.012 14.2 6.7 0.015 13.9 6.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Bac_rhodopsin PF01036.18 KPA44344.1 - 0.3 10.6 12.4 0.077 12.6 8.0 2.0 2 0 0 2 2 2 0 Bacteriorhodopsin-like protein DUF368 PF04018.13 KPA44344.1 - 4.9 6.7 9.8 4.6 6.8 3.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF368) CLTH PF10607.9 KPA44345.1 - 2.8e-31 108.4 0.0 4.8e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KPA44345.1 - 1.2e-07 31.6 3.2 2.3e-07 30.7 3.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPA44345.1 - 2.8e-05 24.0 1.5 5.3e-05 23.1 1.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KPA44345.1 - 0.00029 20.6 2.7 0.00059 19.6 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA44345.1 - 0.0003 21.1 1.6 0.00058 20.2 1.6 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KPA44345.1 - 0.00084 19.2 1.7 0.0016 18.3 1.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KPA44345.1 - 0.0022 17.8 1.9 0.0039 17.0 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA44345.1 - 0.0051 16.6 2.3 0.011 15.6 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KPA44345.1 - 0.0054 16.1 0.1 0.0099 15.3 0.1 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger Cwf_Cwc_15 PF04889.12 KPA44345.1 - 0.0098 15.6 3.5 0.017 14.8 3.5 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein zf-C3HC4_4 PF15227.6 KPA44345.1 - 0.012 15.7 2.5 0.025 14.7 2.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KPA44345.1 - 0.033 14.0 2.1 0.078 12.8 2.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Sigma70_ner PF04546.13 KPA44345.1 - 0.035 14.0 2.9 0.098 12.5 1.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region KRAB PF01352.27 KPA44345.1 - 0.051 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 KRAB box zf-C2HC5 PF06221.13 KPA44345.1 - 0.094 12.7 0.3 0.2 11.7 0.3 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type HEXIM PF15313.6 KPA44345.1 - 0.32 11.2 4.9 0.61 10.3 4.9 1.4 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein PBP1_TM PF14812.6 KPA44345.1 - 0.47 10.8 5.7 0.93 9.9 5.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KPA44345.1 - 0.64 9.7 2.6 1.2 8.8 2.6 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KPA44345.1 - 2 7.7 7.9 0.16 11.3 3.4 1.5 2 0 0 2 2 2 0 NOA36 protein PG_binding_1 PF01471.18 KPA44346.1 - 0.0076 16.4 0.0 2.1 8.6 0.0 2.7 2 0 0 2 2 2 2 Putative peptidoglycan binding domain Spc7 PF08317.11 KPA44346.1 - 0.29 10.0 5.1 0.5 9.2 5.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 KPA44346.1 - 0.49 11.1 4.3 0.16 12.6 0.8 2.0 2 0 0 2 2 2 0 SlyX BLOC1_2 PF10046.9 KPA44346.1 - 0.77 10.1 3.7 1.1 9.6 1.4 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 KPA44346.1 - 1.4 9.4 5.6 5 7.7 1.3 2.4 1 1 1 2 2 2 0 Spectrin repeat LRRFIP PF09738.9 KPA44346.1 - 3.9 6.9 7.3 3 7.3 0.4 2.2 1 1 1 2 2 2 0 LRRFIP family zf-Tim10_DDP PF02953.15 KPA44347.1 - 4.1e-20 71.2 3.9 4.8e-20 71.0 3.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Inhibitor_I34 PF10466.9 KPA44347.1 - 0.061 13.9 0.6 5.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 Aldedh PF00171.22 KPA44348.1 - 4.7e-144 480.3 0.7 5.5e-144 480.1 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPA44348.1 - 0.00039 19.9 0.1 0.00062 19.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) NAD_binding_3 PF03447.16 KPA44348.1 - 0.0042 17.7 0.2 0.0095 16.6 0.2 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Zn_clus PF00172.18 KPA44350.1 - 6.4e-06 26.2 10.3 6.4e-06 26.2 10.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_47 PF01532.20 KPA44352.1 - 2.3e-115 386.1 0.0 2.9e-115 385.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pribosyltran PF00156.27 KPA44353.1 - 3.1e-18 65.8 0.0 4.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KPA44353.1 - 0.0055 16.2 0.0 0.008 15.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CmcI PF04989.12 KPA44353.1 - 0.24 11.1 0.1 0.41 10.3 0.1 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Cytochrom_B558a PF05038.13 KPA44354.1 - 0.21 11.2 1.2 0.67 9.5 0.2 2.3 2 1 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Pex2_Pex12 PF04757.14 KPA44355.1 - 1.3e-34 119.7 1.6 1.9e-34 119.2 1.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KPA44355.1 - 0.00038 20.6 4.0 0.00079 19.5 4.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KPA44355.1 - 0.0055 16.7 1.3 0.018 15.1 1.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KPA44355.1 - 0.022 14.6 1.5 0.046 13.6 1.5 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA44355.1 - 0.11 12.4 4.9 0.12 12.2 1.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPA44355.1 - 1.2 9.0 10.5 2.1 8.2 5.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA44358.1 - 5.4e-10 39.5 8.4 8.7e-10 38.8 8.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPA44358.1 - 4.4e-07 29.6 7.3 7.3e-07 28.9 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KPA44358.1 - 4.4e-06 26.9 5.5 9.6e-06 25.8 5.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KPA44358.1 - 8.9e-06 25.5 8.4 1.5e-05 24.8 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPA44358.1 - 2e-05 24.2 8.9 2e-05 24.2 8.9 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KPA44358.1 - 0.00014 21.8 8.2 0.00022 21.1 8.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPA44358.1 - 0.00029 20.8 2.9 0.00029 20.8 2.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KPA44358.1 - 0.00073 19.5 2.3 0.0013 18.7 2.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KPA44358.1 - 0.001 18.7 4.9 0.0019 17.8 4.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KPA44358.1 - 0.0046 16.8 7.8 0.009 15.8 7.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KPA44358.1 - 0.01 15.7 6.0 0.017 14.9 6.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YdjO PF14169.6 KPA44358.1 - 0.015 15.0 0.3 2.3 8.0 0.2 2.7 2 0 0 2 2 2 0 Cold-inducible protein YdjO zf-C3HC4_4 PF15227.6 KPA44358.1 - 0.017 15.2 6.7 0.031 14.4 6.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KPA44358.1 - 0.027 14.8 0.5 0.057 13.7 0.5 1.5 1 0 0 1 1 1 0 RING-like domain Rtf2 PF04641.12 KPA44358.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger LapA_dom PF06305.11 KPA44358.1 - 0.25 11.2 2.4 0.22 11.4 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain zf-RING_4 PF14570.6 KPA44358.1 - 0.26 11.1 3.2 0.42 10.4 3.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KPA44358.1 - 0.32 10.9 5.6 0.69 9.8 5.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KPA44358.1 - 0.42 10.8 4.3 1.3 9.2 4.3 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KPA44358.1 - 0.78 9.7 5.8 1.3 9.0 5.8 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 KPA44358.1 - 3.2 7.9 5.4 5.5 7.2 5.4 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 KPA44358.1 - 3.6 7.7 6.1 7.5 6.7 6.1 1.6 1 0 0 1 1 1 0 Zinc-finger Het-C PF07217.11 KPA44359.1 - 6.4e-235 781.0 0.0 8.4e-235 780.6 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C HMG_box PF00505.19 KPA44360.1 - 1.9e-06 28.2 0.2 3.9e-06 27.2 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KPA44360.1 - 0.0051 17.4 0.1 0.017 15.7 0.1 1.9 1 0 0 1 1 1 1 HMG-box domain Mpv17_PMP22 PF04117.12 KPA44361.1 - 6.5e-25 87.1 2.0 1.2e-24 86.3 2.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family TetR_C_20 PF17925.1 KPA44361.1 - 0.1 12.9 0.7 0.64 10.4 0.6 2.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1713 PF08213.11 KPA44362.1 - 3.9e-10 39.5 21.9 3.9e-10 39.5 21.9 2.0 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KPA44362.1 - 0.0018 19.0 0.3 0.0044 17.7 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial protein Pet20 GNAT_acetyltr_2 PF13718.6 KPA44363.1 - 2.8e-99 331.1 0.1 7.3e-99 329.8 0.0 1.8 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KPA44363.1 - 1.2e-91 306.7 0.0 1.2e-91 306.7 0.0 1.7 2 0 0 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KPA44363.1 - 2e-64 216.7 0.0 8.8e-64 214.6 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KPA44363.1 - 1.5e-33 114.6 0.0 4.5e-33 113.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KPA44363.1 - 0.00038 20.2 0.3 0.0094 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPA44363.1 - 0.00081 19.7 0.1 0.076 13.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 KPA44363.1 - 0.02 15.1 0.0 1.1 9.6 0.0 2.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family GHMP_kinases_N PF00288.26 KPA44363.1 - 0.17 12.1 0.2 0.47 10.7 0.2 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain Methyltransf_25 PF13649.6 KPA44365.1 - 4.7e-16 59.3 0.0 4.6e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA44365.1 - 1.9e-12 47.3 0.0 3.3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA44365.1 - 4.2e-12 46.5 0.0 4.5e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA44365.1 - 4.4e-11 43.4 0.0 8.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA44365.1 - 1.3e-09 38.1 0.0 2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KPA44365.1 - 2.8e-06 27.3 0.0 4.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KPA44365.1 - 4.9e-05 23.0 0.0 7.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KPA44365.1 - 0.00091 18.4 0.0 0.0012 17.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 KPA44365.1 - 0.0025 17.2 0.0 0.0088 15.4 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KPA44365.1 - 0.0045 16.4 0.1 0.0072 15.8 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KPA44365.1 - 0.0086 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KPA44365.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase WLM PF08325.10 KPA44366.1 - 9.2e-55 185.7 0.1 1.4e-54 185.1 0.1 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 KPA44366.1 - 0.1 12.7 1.6 0.23 11.5 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 SVIP PF15811.5 KPA44366.1 - 0.16 12.4 5.2 2.1 8.9 1.0 2.4 2 0 0 2 2 2 0 Small VCP/p97-interacting protein HATPase_c PF02518.26 KPA44367.1 - 6.7e-29 100.7 0.1 1.2e-28 99.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPA44367.1 - 1.2e-21 76.9 0.1 2.8e-21 75.8 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KPA44367.1 - 1.8e-21 76.0 0.1 4.9e-21 74.5 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KPA44367.1 - 8.9e-20 70.8 0.3 2.9e-19 69.2 0.3 2.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KPA44367.1 - 1.4e-13 50.9 0.0 5.4e-08 33.0 0.0 3.9 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KPA44367.1 - 1.6e-12 47.6 1.5 5.3e-09 36.3 0.0 4.7 4 2 0 4 4 4 1 PAS fold PAS PF00989.25 KPA44367.1 - 7.6e-12 45.2 0.0 9.1e-06 25.7 0.0 4.1 4 0 0 4 4 4 3 PAS fold PAS_8 PF13188.7 KPA44367.1 - 3.2e-08 33.4 0.1 0.051 13.6 0.0 4.4 4 0 0 4 4 4 2 PAS domain PAS_11 PF14598.6 KPA44367.1 - 0.014 15.5 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 PAS domain C2 PF00168.30 KPA44368.1 - 7.3e-23 80.8 0.0 1.8e-12 47.4 0.0 2.7 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 KPA44368.1 - 0.021 14.3 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain FAD_binding_8 PF08022.12 KPA44369.1 - 1.7e-22 79.6 0.0 3.6e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KPA44369.1 - 2e-21 76.7 0.0 3.2e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KPA44369.1 - 5.2e-20 71.8 9.2 5.2e-20 71.8 9.2 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component Amidohydro_1 PF01979.20 KPA44370.1 - 6.5e-72 242.7 0.4 1.1e-71 241.9 0.4 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KPA44370.1 - 1.4e-53 180.4 2.5 1.4e-53 180.4 2.5 1.9 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KPA44370.1 - 2.2e-42 143.0 0.0 5.5e-42 141.8 0.0 1.7 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KPA44370.1 - 5.2e-40 135.7 0.4 1.2e-39 134.5 0.1 1.8 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KPA44370.1 - 9.1e-11 41.9 0.4 6.5e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Ada3 PF10198.9 KPA44371.1 - 1.3e-55 187.2 2.1 1.3e-55 187.2 0.1 2.1 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF3419 PF11899.8 KPA44372.1 - 1.3e-165 551.3 0.0 1.8e-165 550.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KPA44372.1 - 3e-13 50.0 0.0 3.9e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA44372.1 - 8.3e-09 36.1 0.0 5.5e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA44372.1 - 7.1e-07 29.9 0.0 3.7e-05 24.3 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA44372.1 - 8.7e-07 28.8 0.0 3e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA44372.1 - 1.2e-06 28.0 0.2 0.0071 15.7 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KPA44372.1 - 4.8e-06 27.1 0.0 0.00054 20.5 0.0 3.4 3 0 0 3 3 3 1 Methyltransferase domain PCMT PF01135.19 KPA44372.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2516 PF10724.9 KPA44372.1 - 0.093 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) CybS PF05328.12 KPA44373.1 - 5.8e-52 174.9 0.0 7.3e-52 174.6 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit LrgB PF04172.16 KPA44373.1 - 0.011 15.2 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 LrgB-like family tRNA-synt_1b PF00579.25 KPA44374.1 - 8.7e-76 255.0 0.0 1.3e-75 254.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KPA44374.1 - 4.7e-45 152.3 0.0 9.5e-45 151.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain NPR2 PF06218.11 KPA44375.1 - 1.7e-118 396.1 0.0 9.3e-98 327.8 0.0 2.5 1 1 1 2 2 2 2 Nitrogen permease regulator 2 ubiquitin PF00240.23 KPA44376.1 - 2.3e-18 65.7 0.1 3.3e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KPA44376.1 - 3.1e-06 27.0 7.3 6.1e-06 26.0 0.0 3.4 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.8 KPA44376.1 - 0.00016 21.5 0.1 0.00026 20.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KPA44376.1 - 0.00073 19.6 0.2 0.0012 18.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KPA44376.1 - 0.0041 17.7 0.1 0.009 16.6 0.1 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 KPA44376.1 - 0.016 15.2 0.1 0.039 14.0 0.0 1.6 2 0 0 2 2 2 0 HOIP UBA domain pair CUE PF02845.16 KPA44376.1 - 0.13 12.0 0.7 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 CUE domain GerD PF17898.1 KPA44376.1 - 2.7 8.0 11.0 0.14 12.2 4.2 2.2 2 1 0 2 2 2 0 Spore germination GerD central core domain ADH_zinc_N PF00107.26 KPA44377.1 - 9.2e-31 106.5 0.2 1.5e-30 105.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA44377.1 - 2e-09 38.6 0.0 3.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA44377.1 - 7.5e-05 22.6 0.0 0.00019 21.3 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KPA44377.1 - 0.00032 20.9 0.1 0.00062 20.0 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KPA44377.1 - 0.0045 16.3 0.3 0.0081 15.5 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IBN_N PF03810.19 KPA44378.1 - 3.5e-13 49.3 4.0 3.9e-13 49.1 0.4 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KPA44378.1 - 0.00049 20.2 0.2 0.031 14.3 0.0 3.5 2 1 1 3 3 3 1 Exportin 1-like protein Cse1 PF08506.10 KPA44378.1 - 0.0069 15.3 0.0 0.18 10.6 0.0 2.3 2 0 0 2 2 2 1 Cse1 UME PF08064.13 KPA44378.1 - 0.025 14.5 0.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 UME (NUC010) domain Telomere_reg-2 PF10193.9 KPA44378.1 - 0.047 14.1 0.1 1.7 9.1 0.0 2.8 2 0 0 2 2 2 0 Telomere length regulation protein tRNA-synt_2b PF00587.25 KPA44379.1 - 1e-32 113.6 0.0 9.1e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KPA44379.1 - 4.6e-06 26.7 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain HLH PF00010.26 KPA44380.1 - 6.7e-09 35.6 0.0 1.5e-08 34.4 0.0 1.6 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Maf PF02545.14 KPA44381.1 - 1.5e-48 164.7 0.0 1.8e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DUF5616 PF18481.1 KPA44381.1 - 0.19 12.1 0.1 0.3 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5616) Bromodomain PF00439.25 KPA44382.1 - 2.5e-28 97.9 0.1 2.4e-13 50.0 0.0 2.5 2 0 0 2 2 2 2 Bromodomain CDC45 PF02724.14 KPA44382.1 - 0.012 14.0 8.6 0.017 13.4 8.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KPA44382.1 - 0.016 13.4 11.2 0.022 13.0 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KPA44382.1 - 0.1 12.0 13.3 0.15 11.4 13.3 1.2 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 KPA44382.1 - 0.24 11.5 17.8 0.5 10.5 17.8 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Roughex PF06020.11 KPA44382.1 - 0.78 8.8 11.0 1.7 7.6 11.0 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Astro_capsid_p PF12226.8 KPA44382.1 - 1 8.4 10.9 1.7 7.7 10.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TRAP_alpha PF03896.16 KPA44382.1 - 6.5 5.9 11.4 11 5.1 11.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 KPA44382.1 - 7.1 5.8 16.7 11 5.2 16.7 1.2 1 0 0 1 1 1 0 NOA36 protein GEN1_C PF18380.1 KPA44382.1 - 8.6 7.3 11.5 28 5.7 11.5 1.9 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Sigma70_ner PF04546.13 KPA44382.1 - 10 6.0 16.2 27 4.6 16.2 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3844 PF12955.7 KPA44384.1 - 5.6e-35 119.7 4.7 8.3e-35 119.1 4.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Zn_clus PF00172.18 KPA44385.1 - 2.1 8.6 15.8 3.6 7.8 15.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_1d PF00750.19 KPA44386.1 - 4.5e-59 200.1 1.3 4.5e-59 200.1 1.3 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KPA44386.1 - 4e-12 46.4 0.3 1.4e-11 44.6 0.1 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain DUF2207 PF09972.9 KPA44386.1 - 0.0037 16.1 0.1 0.0063 15.3 0.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF1218 PF06749.12 KPA44386.1 - 2.5 8.7 4.3 2.8 8.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Rhodanese PF00581.20 KPA44387.1 - 3.1e-08 34.1 0.0 4.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain LSM PF01423.22 KPA44388.1 - 5.9e-21 73.9 0.8 6.6e-21 73.8 0.8 1.0 1 0 0 1 1 1 1 LSM domain FMO-like PF00743.19 KPA44390.1 - 5.8e-18 64.6 0.0 3.2e-16 58.9 0.0 2.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPA44390.1 - 1.2e-11 44.4 0.0 2.9e-11 43.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA44390.1 - 7.6e-09 35.7 0.0 8.6e-07 29.1 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA44390.1 - 3.6e-08 33.0 0.0 1.1e-05 24.8 0.0 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA44390.1 - 1.3e-07 31.5 0.1 0.035 13.7 0.0 4.3 4 1 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KPA44390.1 - 3.2e-07 29.8 0.1 2.1e-05 23.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KPA44390.1 - 2.4e-06 27.0 0.0 0.0004 19.7 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KPA44390.1 - 7.2e-06 26.5 0.0 0.016 15.8 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA44390.1 - 0.00012 21.5 0.1 0.044 13.0 0.0 2.7 3 1 0 3 3 3 2 FAD binding domain Shikimate_DH PF01488.20 KPA44390.1 - 0.0068 16.5 0.0 0.13 12.3 0.0 2.5 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KPA44390.1 - 0.017 15.1 0.9 82 3.2 0.0 4.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding Mqo PF06039.15 KPA44390.1 - 0.048 12.2 0.0 1.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 KPA44390.1 - 0.073 12.1 0.0 6.7 5.6 0.0 2.6 2 1 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KPA44390.1 - 0.077 11.7 0.0 12 4.4 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein Amino_oxidase PF01593.24 KPA44390.1 - 0.12 11.7 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Malic_M PF03949.15 KPA44390.1 - 0.15 11.3 0.0 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain RRM_1 PF00076.22 KPA44391.1 - 1.3e-21 76.2 0.0 2.1e-10 40.2 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPA44391.1 - 0.00038 20.2 0.0 0.039 13.8 0.0 2.4 2 1 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KPA44391.1 - 0.026 14.1 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOR PF05036.13 KPA44391.1 - 0.14 12.5 0.0 18 5.8 0.0 2.6 2 0 0 2 2 2 0 Sporulation related domain zf-LITAF-like PF10601.9 KPA44392.1 - 5.9e-15 55.3 0.6 8.3e-15 54.8 0.6 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Lar_restr_allev PF14354.6 KPA44392.1 - 0.057 13.8 0.2 0.12 12.8 0.2 1.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF1328 PF07043.13 KPA44392.1 - 0.52 10.6 1.1 0.79 10.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1328) Sgf11 PF08209.11 KPA44392.1 - 0.66 9.6 3.0 1.1 8.9 0.2 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) GST_N_2 PF13409.6 KPA44393.1 - 2.1e-08 34.4 0.1 4.4e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPA44393.1 - 3.3e-08 33.8 0.0 2.2e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPA44393.1 - 1.1e-07 31.8 0.0 2.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA44393.1 - 0.00089 19.4 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPA44393.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KPA44393.1 - 0.16 12.5 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OTT_1508_deam PF14441.6 KPA44394.1 - 2.2e-17 62.8 0.0 4.6e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase NAD_binding_1 PF00175.21 KPA44395.1 - 1.4e-09 38.5 0.0 3.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KPA44395.1 - 3.3e-07 30.8 0.0 6.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 KPA44395.1 - 0.00015 22.0 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 KPA44395.1 - 0.0062 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Protoglobin FAD_binding_8 PF08022.12 KPA44395.1 - 0.0067 16.5 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KPA44395.1 - 0.0078 16.3 0.4 0.097 12.8 0.2 2.6 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Fib_alpha PF08702.10 KPA44395.1 - 0.2 11.8 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TPR_1 PF00515.28 KPA44396.1 - 2.9e-42 140.8 22.6 3.6e-08 32.9 0.6 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KPA44396.1 - 5.2e-37 125.6 8.1 3.7e-20 71.6 0.2 2.8 3 0 0 3 3 2 2 STI1 domain TPR_2 PF07719.17 KPA44396.1 - 9e-34 112.9 23.3 6.2e-06 25.9 0.3 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.6 KPA44396.1 - 1.9e-16 60.4 5.3 5.9e-05 23.6 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPA44396.1 - 2.2e-15 56.7 14.5 1.1e-10 41.6 0.2 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPA44396.1 - 6.7e-15 54.0 5.9 0.00011 22.0 0.2 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KPA44396.1 - 8.8e-15 54.1 21.5 0.0015 18.2 0.3 8.0 7 1 2 9 9 8 4 TPR repeat TPR_8 PF13181.6 KPA44396.1 - 1.2e-14 53.2 28.7 0.00017 21.5 0.4 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KPA44396.1 - 7.5e-13 48.1 6.2 2.2 9.3 0.0 7.9 4 3 4 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPA44396.1 - 2.3e-12 47.2 9.0 0.00022 21.7 0.1 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KPA44396.1 - 3.5e-10 39.5 3.2 2.6 8.6 0.1 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 KPA44396.1 - 7.3e-10 38.9 0.6 0.0018 18.4 0.0 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KPA44396.1 - 5.3e-07 29.9 10.9 0.38 11.5 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KPA44396.1 - 0.00012 21.8 14.2 0.00083 19.2 0.1 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat MIT PF04212.18 KPA44396.1 - 0.0033 17.4 12.0 2 8.6 0.2 6.2 6 0 0 6 6 6 2 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KPA44396.1 - 0.023 14.7 13.6 0.17 11.9 0.4 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KPA44396.1 - 0.06 12.8 0.9 2.1 7.9 0.1 3.2 3 0 0 3 3 3 0 SHNi-TPR RPN7 PF10602.9 KPA44396.1 - 0.087 12.5 7.6 0.76 9.5 2.6 4.2 3 2 0 3 3 3 0 26S proteasome subunit RPN7 ANAPC3 PF12895.7 KPA44396.1 - 0.1 12.9 6.7 1.7 8.9 0.4 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KPA44396.1 - 0.28 11.5 7.6 2.6 8.4 0.2 4.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPM_phosphatase PF04536.14 KPA44396.1 - 0.42 10.8 8.7 8.5 6.6 0.1 4.4 4 1 1 5 5 5 0 TPM domain XPC-binding PF09280.11 KPA44396.1 - 0.45 10.3 4.5 1.7 8.5 1.7 2.9 3 0 0 3 3 3 0 XPC-binding domain DUF5486 PF17588.2 KPA44396.1 - 6.8 6.7 6.7 10 6.1 1.6 2.8 3 0 0 3 3 2 0 Family of unknown function (DUF5486) DUF3391 PF11871.8 KPA44396.1 - 8.3 6.9 15.6 0.05 14.1 1.4 3.2 2 1 0 2 2 1 0 Domain of unknown function (DUF3391) Glyco_hydro_3 PF00933.21 KPA44397.1 - 1.2e-57 195.7 0.0 2e-57 195.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KPA44397.1 - 6.5e-54 183.0 0.1 2.9e-53 180.9 0.0 2.0 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KPA44397.1 - 2e-22 79.1 0.5 5.4e-22 77.7 0.2 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KPA44397.1 - 5.4e-06 26.3 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Zip PF02535.22 KPA44398.1 - 3.9e-57 194.0 0.1 4.8e-57 193.7 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Sdh_cyt PF01127.22 KPA44398.1 - 0.56 10.2 0.1 0.56 10.2 0.1 2.7 4 0 0 4 4 4 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Hemerythrin PF01814.23 KPA44399.1 - 3.3e-09 37.4 0.3 4.5e-09 37.0 0.3 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain NAD_binding_10 PF13460.6 KPA44400.1 - 2.9e-23 82.7 0.2 3.8e-23 82.3 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPA44400.1 - 8.1e-05 22.2 0.0 0.00019 20.9 0.0 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA44400.1 - 0.012 15.0 0.1 0.08 12.3 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KPA44400.1 - 0.02 14.0 0.1 0.066 12.3 0.1 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 KPA44400.1 - 0.026 14.1 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Presenilin PF01080.17 KPA44401.1 - 0.058 12.2 1.3 0.058 12.2 1.3 1.0 1 0 0 1 1 1 0 Presenilin Dicty_REP PF05086.12 KPA44401.1 - 0.3 9.0 6.2 0.34 8.8 6.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hamartin PF04388.12 KPA44401.1 - 0.55 8.8 12.2 0.61 8.7 12.2 1.0 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 KPA44401.1 - 0.63 10.0 9.1 0.74 9.7 9.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 KPA44401.1 - 1.9 8.3 13.9 2.2 8.1 13.9 1.0 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KPA44401.1 - 2 7.2 6.3 2.2 7.0 6.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KPA44401.1 - 2.6 6.5 5.4 2.9 6.4 5.4 1.0 1 0 0 1 1 1 0 Macoilin family DUF5427 PF10310.9 KPA44401.1 - 3.7 6.4 10.2 4.4 6.1 10.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) G_path_suppress PF15991.5 KPA44401.1 - 3.9 7.5 12.3 4.7 7.3 12.3 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor DIE2_ALG10 PF04922.12 KPA44402.1 - 4.1e-125 418.2 2.9 5.7e-124 414.4 2.9 2.0 1 1 0 1 1 1 1 DIE2/ALG10 family QCR10 PF09796.9 KPA44403.1 - 3e-26 91.3 0.1 3.8e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Med4 PF10018.9 KPA44404.1 - 6.4e-38 130.4 14.8 1.2e-37 129.4 14.8 1.5 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 ZnuA PF01297.17 KPA44404.1 - 0.048 13.1 0.1 0.23 10.8 0.1 2.0 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic DDRGK PF09756.9 KPA44404.1 - 0.12 12.0 18.1 0.23 11.1 18.1 1.4 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.12 KPA44404.1 - 0.33 10.7 5.5 0.67 9.7 5.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EMP70 PF02990.16 KPA44405.1 - 9.1e-202 671.3 4.9 1.3e-201 670.8 4.9 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Sas10_Utp3 PF04000.15 KPA44406.1 - 3.2e-16 59.7 4.6 3.2e-16 59.7 4.6 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF3069 PF11269.8 KPA44406.1 - 5.3 7.3 5.7 0.51 10.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) Sin_N PF04801.13 KPA44407.1 - 2.4e-21 76.5 0.1 4e-21 75.8 0.1 1.3 1 1 0 1 1 1 1 Sin-like protein conserved region PHY PF00360.20 KPA44407.1 - 0.044 13.1 0.2 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Phytochrome region PAT1 PF09770.9 KPA44408.1 - 0 1254.2 13.9 0 1249.5 13.9 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.16 KPA44409.1 - 1.9e-130 434.9 4.7 2.4e-130 434.5 4.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.25 KPA44410.1 - 5.7e-29 100.0 0.7 7.9e-29 99.6 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 KPA44410.1 - 0.21 12.3 0.0 0.49 11.1 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein S12 Acyl-CoA_dh_1 PF00441.24 KPA44411.1 - 5.7e-40 137.0 4.7 1e-39 136.1 4.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPA44411.1 - 1.1e-30 106.6 0.3 4.4e-30 104.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KPA44411.1 - 2.7e-23 82.0 0.0 6.4e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPA44411.1 - 3.1e-17 63.1 1.9 5.5e-17 62.3 1.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KPA44411.1 - 0.00021 21.1 0.1 0.0025 17.5 0.0 2.3 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 KPA44411.1 - 0.026 14.6 0.0 0.081 13.0 0.0 1.8 1 0 0 1 1 1 0 Staphylococcal AgrD protein Pkinase PF00069.25 KPA44412.1 - 1.5e-60 204.8 0.0 3.2e-60 203.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA44412.1 - 1e-35 123.3 0.0 1.7e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KPA44412.1 - 2.5e-24 85.2 17.7 1.8e-12 47.2 5.4 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KPA44412.1 - 5.8e-20 70.9 30.7 5.6e-12 45.4 11.2 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KPA44412.1 - 3e-14 53.4 1.0 1.1e-13 51.6 1.0 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KPA44412.1 - 0.0052 16.1 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-RING_9 PF13901.6 KPA44412.1 - 1.6 8.7 22.7 1.2 9.0 7.8 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PAT1 PF09770.9 KPA44412.1 - 3.6 5.7 10.2 6.1 5.0 10.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 She9_MDM33 PF05546.11 KPA44413.1 - 2.6e-80 268.9 8.0 3.8e-80 268.4 8.0 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family KxDL PF10241.9 KPA44413.1 - 0.39 11.0 9.0 3.1 8.1 0.3 4.0 5 0 0 5 5 5 0 Uncharacterized conserved protein HAD PF12710.7 KPA44414.1 - 2.9e-24 86.5 0.0 3.8e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KPA44414.1 - 3.5e-05 23.5 0.0 8.1e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 KPA44414.1 - 0.002 17.6 0.0 0.064 12.6 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.26 KPA44414.1 - 0.0023 18.2 0.2 0.036 14.4 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KPA44415.1 - 2e-22 79.6 54.3 4.8e-12 45.5 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA44415.1 - 0.0019 16.9 17.0 0.0019 16.9 17.0 2.7 1 1 1 2 2 2 1 MFS/sugar transport protein Phage_holin_2_4 PF16082.5 KPA44415.1 - 0.13 12.0 5.5 0.47 10.2 0.0 3.7 4 0 0 4 4 4 0 Bacteriophage holin family, superfamily II-like Srg PF02118.21 KPA44415.1 - 0.18 11.4 5.5 0.067 12.8 1.4 2.2 1 1 1 2 2 2 0 Srg family chemoreceptor eIF-1a PF01176.19 KPA44416.1 - 1.5e-19 69.6 0.0 2e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.13 KPA44417.1 - 1.1e-141 472.4 19.1 1.3e-141 472.2 19.1 1.0 1 0 0 1 1 1 1 ALG3 protein DAO PF01266.24 KPA44418.1 - 1.4e-38 133.4 0.1 1.6e-38 133.2 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA44418.1 - 3.1e-05 24.1 0.1 6.8e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPA44418.1 - 7.4e-05 22.1 0.2 7.4e-05 22.1 0.2 2.2 2 1 1 3 3 3 1 Thi4 family FAD_binding_2 PF00890.24 KPA44418.1 - 0.0049 16.0 0.0 0.0071 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KPA44418.1 - 0.006 17.1 0.3 0.018 15.6 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA44418.1 - 0.019 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EspF PF04806.12 KPA44418.1 - 0.019 15.4 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 EspF protein repeat Capsid-VNN PF11729.8 KPA44418.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 nodavirus capsid protein ApbA PF02558.16 KPA44418.1 - 0.17 11.5 1.3 0.68 9.6 0.3 2.3 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Thioredoxin PF00085.20 KPA44419.1 - 1e-26 92.9 0.0 1.4e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KPA44419.1 - 1.7e-05 24.6 0.0 2.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KPA44419.1 - 1.7e-05 25.0 0.0 0.00024 21.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KPA44419.1 - 3.1e-05 24.4 0.1 9.3e-05 22.8 0.1 1.8 2 1 0 2 2 2 1 Thioredoxin-like domain Glutaredoxin PF00462.24 KPA44419.1 - 0.00074 19.7 0.0 0.0015 18.7 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin Redoxin PF08534.10 KPA44419.1 - 0.00087 19.0 0.3 0.008 15.9 0.2 2.0 1 1 1 2 2 2 1 Redoxin OST3_OST6 PF04756.13 KPA44419.1 - 0.0011 18.4 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KPA44419.1 - 0.0023 18.1 0.0 0.0037 17.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KPA44419.1 - 0.0038 17.1 0.0 0.0062 16.4 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 KPA44419.1 - 0.013 15.3 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein MscL PF01741.18 KPA44420.1 - 9.5e-20 71.1 0.1 1.2e-19 70.8 0.1 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DZR PF12773.7 KPA44420.1 - 0.028 14.4 0.8 0.042 13.9 0.8 1.2 1 0 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.22 KPA44420.1 - 0.028 14.3 2.6 0.042 13.7 2.6 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KPA44420.1 - 0.35 10.5 2.8 0.52 10.0 2.8 1.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Glyco_hydro_76 PF03663.14 KPA44423.1 - 1.9e-130 435.7 4.0 2.3e-130 435.4 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Mucin PF01456.17 KPA44423.1 - 0.73 9.8 6.4 4 7.4 0.3 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Aminotran_1_2 PF00155.21 KPA44424.1 - 1.2e-62 212.2 0.0 1.4e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KPA44424.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Allinase Cu-oxidase_2 PF07731.14 KPA44425.1 - 7.7e-37 126.1 7.9 2.2e-35 121.4 0.4 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KPA44425.1 - 5.5e-34 116.7 2.4 6.6e-33 113.2 0.8 3.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 KPA44425.1 - 2.1e-33 115.7 0.2 4.4e-33 114.6 0.1 1.6 2 0 0 2 2 2 1 Multicopper oxidase ECM11 PF15463.6 KPA44426.1 - 5.4e-41 140.3 8.1 5.4e-41 140.3 8.1 2.4 2 1 1 3 3 3 1 Extracellular mutant protein 11 Not3 PF04065.15 KPA44426.1 - 0.5 9.7 8.8 0.073 12.5 4.0 1.8 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component KAP_NTPase PF07693.14 KPA44427.1 - 7.2e-06 25.5 0.0 9.9e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain SRP54 PF00448.22 KPA44427.1 - 0.00033 20.4 0.0 0.00043 20.0 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KPA44427.1 - 0.0006 20.4 0.0 0.0013 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KPA44427.1 - 0.0032 16.5 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 KPA44427.1 - 0.0049 16.6 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KPA44427.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KPA44427.1 - 0.013 15.8 0.0 0.02 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain dNK PF01712.19 KPA44427.1 - 0.014 15.2 0.0 0.032 14.1 0.0 1.6 2 0 0 2 2 2 0 Deoxynucleoside kinase APS_kinase PF01583.20 KPA44427.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 KPA44427.1 - 0.027 15.0 0.0 0.05 14.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KPA44427.1 - 0.044 13.8 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KPA44427.1 - 0.045 13.7 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Thymidylate_kin PF02223.17 KPA44427.1 - 0.048 13.3 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase NB-ARC PF00931.22 KPA44427.1 - 0.052 12.7 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Arf PF00025.21 KPA44427.1 - 0.061 12.8 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_33 PF13671.6 KPA44427.1 - 0.07 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KPA44427.1 - 0.098 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KPA44427.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KPA44427.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KPA44427.1 - 0.17 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KPA44427.1 - 0.17 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KPA44427.1 - 0.17 11.8 0.1 0.27 11.1 0.1 1.2 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.17 KPA44427.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein adh_short PF00106.25 KPA44428.1 - 9.2e-83 276.5 10.7 8e-44 149.4 0.6 2.6 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA44428.1 - 2e-66 223.9 4.4 2.3e-35 122.2 0.2 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KPA44428.1 - 2.1e-33 114.5 0.0 3.8e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KPA44428.1 - 3e-30 105.5 2.2 5.5e-14 52.5 0.4 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KPA44428.1 - 0.00034 20.0 1.0 0.00089 18.6 0.7 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MaoC_dehydrat_N PF13452.6 KPA44428.1 - 0.0015 18.7 0.0 2.5 8.3 0.0 2.6 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase PglL_A PF15864.5 KPA44428.1 - 1.1 9.0 6.6 5.4 6.8 1.0 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase IBR PF01485.21 KPA44429.1 - 8.7e-05 22.7 8.2 8.7e-05 22.7 8.2 4.3 3 2 1 4 4 4 2 IBR domain, a half RING-finger domain Cyclin_N PF00134.23 KPA44430.1 - 0.00013 21.7 0.0 0.002 17.9 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain CDP-OH_P_transf PF01066.21 KPA44430.1 - 0.062 14.1 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase PNP_phzG_C PF10590.9 KPA44431.1 - 1.3e-20 73.1 1.8 1.3e-20 73.1 1.8 2.2 3 1 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KPA44431.1 - 5.7e-19 68.1 0.0 9.1e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KPA44431.1 - 0.026 14.1 0.0 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Pyridox_oxase_2 PF12766.7 KPA44431.1 - 0.038 14.6 0.0 0.075 13.6 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.17 KPA44432.1 - 5.6e-114 378.9 0.3 1.2e-84 283.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KPA44432.1 - 1.7e-47 160.4 0.0 3.9e-47 159.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KPA44432.1 - 3.8e-45 154.0 0.0 1.6e-44 152.0 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KPA44432.1 - 6e-45 152.9 0.0 1.3e-44 151.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KPA44432.1 - 3.9e-40 137.0 0.1 8.5e-40 135.9 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KPA44432.1 - 1.9e-29 102.8 0.0 6.7e-29 101.0 0.0 2.0 2 0 0 2 2 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KPA44432.1 - 3.2e-22 78.5 0.0 1.4e-21 76.5 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KPA44432.1 - 6.7e-18 65.0 1.2 5.1e-08 32.7 0.2 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KPA44432.1 - 3e-16 59.5 0.1 5.5e-08 32.6 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KPA44432.1 - 5.9e-11 42.2 0.0 8.9e-06 25.5 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KPA44432.1 - 2.7e-06 27.3 0.3 0.00024 21.0 0.3 2.8 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 KPA44432.1 - 3.8e-05 23.8 0.7 0.14 12.2 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KPA44432.1 - 0.00024 21.0 1.0 0.16 11.8 0.0 4.2 4 0 0 4 4 4 1 DJ-1/PfpI family GARS_A PF01071.19 KPA44432.1 - 0.0004 20.2 0.2 1 9.1 0.0 2.9 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KPA44432.1 - 0.0017 18.0 0.1 0.51 9.9 0.1 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain SOG2 PF10428.9 KPA44433.1 - 0.39 9.8 20.1 0.68 9.1 20.1 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4407 PF14362.6 KPA44433.1 - 4.2 6.6 7.7 0.28 10.5 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TFIIIC_delta PF12657.7 KPA44434.1 - 2.6e-28 99.2 0.0 8.9e-28 97.5 0.0 1.9 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KPA44434.1 - 5.4e-14 52.0 1.7 1.3e-13 50.8 1.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Peptidase_C13 PF01650.18 KPA44435.1 - 1.5e-40 139.3 0.4 2e-40 138.9 0.4 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 KPA44435.1 - 0.061 13.6 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Mid domain of argonaute His_Phos_1 PF00300.22 KPA44436.1 - 3.8e-06 26.7 1.0 0.055 13.2 0.0 3.7 2 2 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Mito_carr PF00153.27 KPA44437.1 - 5.3e-54 180.1 5.4 3.4e-18 65.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_efflux PF01545.21 KPA44438.1 - 5.7e-46 156.8 7.3 7.5e-46 156.4 7.3 1.2 1 0 0 1 1 1 1 Cation efflux family PhaG_MnhG_YufB PF03334.14 KPA44438.1 - 9.1 6.6 6.9 2 8.7 0.4 2.6 2 1 0 2 2 2 0 Na+/H+ antiporter subunit Glyco_trans_1_4 PF13692.6 KPA44439.1 - 1.4e-07 32.1 0.0 1.3e-06 28.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KPA44439.1 - 0.016 15.6 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 UQ_con PF00179.26 KPA44440.1 - 2.7e-35 121.0 0.0 3.3e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPA44440.1 - 0.04 13.6 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 KPA44440.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 zf-C2H2_jaz PF12171.8 KPA44441.1 - 2.4e-05 24.5 0.2 4.8e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 KPA44441.1 - 0.00042 20.3 1.2 0.0017 18.4 1.2 2.1 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-met PF12874.7 KPA44441.1 - 0.0024 18.2 0.1 0.0046 17.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 KPA44441.1 - 0.0031 17.6 0.1 0.0073 16.4 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2 PF00096.26 KPA44441.1 - 0.087 13.3 0.2 0.18 12.3 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DDHD PF02862.17 KPA44441.1 - 9.9 6.2 6.8 2 8.5 3.8 1.4 2 0 0 2 2 2 0 DDHD domain TP_methylase PF00590.20 KPA44442.1 - 6.2e-25 88.4 0.1 1.1e-24 87.6 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pyrid_ox_like PF16242.5 KPA44443.1 - 5.8e-22 77.9 0.0 8.6e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KPA44443.1 - 9.1e-09 35.4 0.0 1.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DNA_pol3_alpha PF07733.12 KPA44443.1 - 0.017 14.7 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain FMN_bind_2 PF04299.12 KPA44443.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative FMN-binding domain SH3_9 PF14604.6 KPA44445.1 - 2.8e-12 46.3 0.0 4.6e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPA44445.1 - 2e-08 33.7 0.0 3.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KPA44445.1 - 1.6e-06 27.7 0.0 2.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain eIF3_subunit PF08597.10 KPA44445.1 - 0.00085 19.3 38.5 0.0015 18.5 38.5 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Nop14 PF04147.12 KPA44445.1 - 0.008 14.5 36.6 0.011 14.0 36.6 1.1 1 0 0 1 1 1 1 Nop14-like family Macoilin PF09726.9 KPA44445.1 - 0.041 12.5 14.6 0.057 12.0 14.6 1.1 1 0 0 1 1 1 0 Macoilin family TFIIF_alpha PF05793.12 KPA44445.1 - 0.098 11.2 37.2 0.21 10.2 37.2 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Borrelia_P83 PF05262.11 KPA44445.1 - 0.22 10.0 33.5 0.3 9.5 33.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Red1 PF07964.11 KPA44445.1 - 0.25 9.6 24.6 0.33 9.2 24.6 1.1 1 0 0 1 1 1 0 Rec10 / Red1 BUD22 PF09073.10 KPA44445.1 - 7 5.9 44.3 11 5.2 44.3 1.3 1 0 0 1 1 1 0 BUD22 SLC12 PF03522.15 KPA44445.1 - 7.2 5.5 20.3 9.8 5.1 20.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Plasmodium_Vir PF05795.11 KPA44445.1 - 7.4 5.9 16.9 14 5.0 16.9 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 KPA44445.1 - 8.6 5.0 26.0 14 4.3 26.0 1.3 1 0 0 1 1 1 0 Presenilin AFG1_ATPase PF03969.16 KPA44446.1 - 1.4e-95 320.3 0.0 3.4e-91 305.8 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.18 KPA44446.1 - 2e-05 24.5 0.2 0.21 11.4 0.0 2.6 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_16 PF13191.6 KPA44446.1 - 3.4e-05 24.3 0.1 0.023 15.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KPA44446.1 - 6e-05 23.1 0.0 0.00015 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KPA44446.1 - 0.00026 21.4 0.0 0.00066 20.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KPA44446.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPA44446.1 - 0.011 16.0 0.0 0.045 14.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPA44446.1 - 0.014 15.8 0.1 0.082 13.3 0.1 2.4 2 1 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 KPA44446.1 - 0.036 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MCM PF00493.23 KPA44446.1 - 0.038 13.1 0.0 0.083 12.0 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain TsaE PF02367.17 KPA44446.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KPA44446.1 - 0.063 13.8 0.0 0.48 11.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter UvrD-helicase PF00580.21 KPA44446.1 - 0.12 11.9 0.0 0.61 9.5 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Mg_chelatase PF01078.21 KPA44446.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KPA44446.1 - 0.16 11.8 0.0 0.79 9.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Cupredoxin_1 PF13473.6 KPA44447.1 - 0.00024 21.1 0.0 0.0027 17.8 0.0 2.1 2 0 0 2 2 2 1 Cupredoxin-like domain NOA36 PF06524.12 KPA44447.1 - 2.9 7.1 6.3 3.7 6.8 6.3 1.1 1 0 0 1 1 1 0 NOA36 protein bZIP_1 PF00170.21 KPA44448.1 - 0.18 11.9 5.6 0.31 11.2 5.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor Metallophos PF00149.28 KPA44450.1 - 1.1e-30 107.7 0.1 6.2e-22 79.1 0.0 2.1 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KPA44450.1 - 0.034 14.6 0.1 0.086 13.3 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 KPA44451.1 - 0.001 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 DUF588 PF04535.12 KPA44452.1 - 0.1 12.4 3.1 0.14 11.9 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Cullin PF00888.22 KPA44453.1 - 2e-193 644.4 13.8 2.6e-193 644.1 13.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KPA44453.1 - 6.7e-26 90.1 3.4 6.7e-26 90.1 3.4 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 KPA44453.1 - 0.0095 16.4 2.6 0.021 15.3 0.4 2.8 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal DUF1803 PF08820.10 KPA44453.1 - 1.4 9.0 9.3 2.6 8.1 0.1 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF1803) Avl9 PF09794.9 KPA44454.1 - 2e-143 477.7 0.0 2.4e-143 477.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KPA44454.1 - 1.2e-06 28.5 0.1 0.00014 21.8 0.0 2.3 1 1 1 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 KPA44454.1 - 7.5e-06 25.7 0.0 0.00048 19.8 0.0 2.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4916 PF16262.5 KPA44454.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) G-alpha PF00503.20 KPA44456.1 - 8.4e-114 380.4 2.5 9.7e-114 380.2 2.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KPA44456.1 - 1.7e-16 60.1 0.3 3.2e-10 39.7 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KPA44456.1 - 6.3e-05 22.4 0.2 0.045 13.1 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KPA44456.1 - 0.0019 18.4 0.0 0.68 10.2 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KPA44456.1 - 0.097 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.20 KPA44457.1 - 0 1051.9 0.0 0 1051.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pkinase PF00069.25 KPA44458.1 - 1.1e-68 231.5 0.0 1.4e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA44458.1 - 2.8e-32 112.0 0.0 3.8e-32 111.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPA44458.1 - 7.4e-06 25.1 0.1 1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KPA44458.1 - 5.8e-05 22.5 0.1 0.00018 20.9 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPA44458.1 - 0.00061 19.8 0.0 0.0017 18.4 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KPA44458.1 - 0.00077 18.9 0.0 0.067 12.5 0.0 2.2 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KPA44458.1 - 0.021 14.4 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KPA44458.1 - 0.023 14.3 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ABC_tran PF00005.27 KPA44459.1 - 3e-50 170.3 0.0 6.6e-29 101.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KPA44459.1 - 5.6e-37 127.9 24.6 4.7e-21 75.7 14.5 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KPA44459.1 - 1.5e-08 34.3 2.5 0.026 14.0 0.6 4.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPA44459.1 - 2.4e-06 28.2 0.2 0.0015 19.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPA44459.1 - 5.5e-06 26.0 2.5 0.044 13.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KPA44459.1 - 1.2e-05 25.0 0.1 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 KPA44459.1 - 1.7e-05 24.1 0.0 0.039 13.1 0.0 3.3 2 2 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 KPA44459.1 - 0.00014 21.8 0.3 0.33 10.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KPA44459.1 - 0.00035 20.7 2.7 0.005 17.0 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 KPA44459.1 - 0.00049 20.5 0.4 1.5 9.2 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain cobW PF02492.19 KPA44459.1 - 0.00067 19.3 0.8 0.19 11.3 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KPA44459.1 - 0.0013 18.6 0.3 3 7.6 0.0 3.7 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KPA44459.1 - 0.0052 17.0 1.6 1.3 9.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KPA44459.1 - 0.0059 16.7 0.4 0.13 12.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Pox_A32 PF04665.12 KPA44459.1 - 0.0059 16.1 2.9 0.81 9.1 0.1 2.4 2 0 0 2 2 2 2 Poxvirus A32 protein NACHT PF05729.12 KPA44459.1 - 0.0068 16.3 0.9 4.5 7.1 0.2 2.6 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 KPA44459.1 - 0.011 15.9 0.1 4.3 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KPA44459.1 - 0.012 15.4 0.0 3.6 7.2 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 KPA44459.1 - 0.016 14.6 0.2 0.4 10.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 KPA44459.1 - 0.016 14.3 1.2 2.9 6.9 0.2 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 KPA44459.1 - 0.029 14.4 2.4 1.2 9.2 0.2 2.6 2 0 0 2 2 2 0 Dynamin family DUF3040 PF11239.8 KPA44459.1 - 0.032 14.5 5.1 0.86 9.9 0.6 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) AAA_30 PF13604.6 KPA44459.1 - 0.053 13.2 0.0 4.7 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KPA44459.1 - 0.056 12.7 0.1 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.18 KPA44459.1 - 0.064 12.5 0.3 6.8 5.9 0.0 2.6 3 0 0 3 3 2 0 Septin DnaB_C PF03796.15 KPA44459.1 - 0.068 12.5 0.0 0.62 9.3 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Roc PF08477.13 KPA44459.1 - 0.08 13.2 0.1 21 5.3 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KPA44459.1 - 0.095 12.4 0.2 11 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KPA44459.1 - 0.13 12.1 1.2 8.3 6.3 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.6 KPA44459.1 - 0.15 12.6 0.0 15 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KPA44459.1 - 0.33 10.4 0.9 2.2 7.7 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 KPA44459.1 - 0.36 10.7 1.2 15 5.5 0.2 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 KPA44459.1 - 0.45 10.6 4.5 9.1 6.3 1.0 3.3 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1774 PF08611.10 KPA44460.1 - 1.3e-35 121.6 5.5 1.3e-35 121.6 5.5 2.5 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) ACPS PF01648.20 KPA44460.1 - 9.1e-08 32.2 0.0 2e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KPA44460.1 - 0.15 12.2 3.3 3.8 7.7 3.3 2.5 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Clr5 PF14420.6 KPA44462.1 - 4.5e-12 46.0 0.3 1.2e-11 44.7 0.3 1.8 1 0 0 1 1 1 1 Clr5 domain AAA_6 PF12774.7 KPA44463.1 - 3.6e-127 423.9 0.0 2.1e-126 421.4 0.0 2.5 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KPA44463.1 - 6.4e-118 394.8 7.2 6.4e-118 394.8 7.2 4.6 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KPA44463.1 - 1.8e-117 392.8 5.8 1.8e-117 392.8 5.8 5.8 4 2 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KPA44463.1 - 2.6e-73 245.8 1.0 2.6e-73 245.8 1.0 3.5 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KPA44463.1 - 3.5e-67 226.5 0.0 5.9e-66 222.4 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KPA44463.1 - 6.7e-42 143.0 0.0 3e-36 124.6 0.0 4.8 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 KPA44463.1 - 1.7e-41 142.4 8.8 1.7e-41 142.4 8.8 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KPA44463.1 - 3.4e-31 108.1 0.0 1.7e-11 44.3 0.0 6.4 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 KPA44463.1 - 1.2e-29 103.3 0.0 4.2e-29 101.5 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KPA44463.1 - 1.9e-28 98.9 0.2 7.3e-27 93.8 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 KPA44463.1 - 8.7e-15 55.2 0.6 0.0099 16.2 0.0 5.9 5 1 0 5 5 4 3 AAA domain Dynein_AAA_lid PF17852.1 KPA44463.1 - 3.7e-14 52.9 0.0 1.4e-13 51.0 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KPA44463.1 - 7.1e-13 49.1 0.0 0.0032 17.9 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPA44463.1 - 2e-10 41.3 0.4 1.8 9.0 0.0 7.3 6 0 0 6 6 5 2 AAA ATPase domain AAA_33 PF13671.6 KPA44463.1 - 8.9e-10 38.9 0.8 0.32 11.2 0.0 5.0 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 KPA44463.1 - 1.4e-09 38.6 0.3 0.07 13.7 0.0 5.7 5 0 0 5 5 4 2 AAA domain AAA_29 PF13555.6 KPA44463.1 - 8.1e-06 25.5 0.0 0.58 9.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 KPA44463.1 - 2e-05 23.8 0.0 0.018 14.1 0.0 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 KPA44463.1 - 2.7e-05 24.3 0.3 0.00035 20.8 0.0 3.1 3 0 0 3 3 2 1 AAA+ lid domain ABC_tran PF00005.27 KPA44463.1 - 8.8e-05 23.0 0.9 5.3 7.6 0.0 5.2 4 0 0 4 4 4 0 ABC transporter Mg_chelatase PF01078.21 KPA44463.1 - 0.00018 20.9 1.1 0.67 9.3 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KPA44463.1 - 0.00027 21.0 0.0 3.6 7.6 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KPA44463.1 - 0.00032 21.0 0.9 0.27 11.5 0.0 4.4 4 0 0 4 4 4 1 AAA domain BRE1 PF08647.11 KPA44463.1 - 0.00085 19.4 2.2 0.00085 19.4 2.2 5.2 4 1 1 5 5 4 1 BRE1 E3 ubiquitin ligase AAA_25 PF13481.6 KPA44463.1 - 0.0012 18.5 0.0 0.22 11.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KPA44463.1 - 0.0012 19.2 0.5 44 4.5 0.0 5.7 6 0 0 6 6 5 0 RNA helicase AAA_30 PF13604.6 KPA44463.1 - 0.0018 18.1 1.5 38 3.9 0.0 5.2 5 0 0 5 5 4 0 AAA domain AAA_24 PF13479.6 KPA44463.1 - 0.0022 17.8 0.3 11 5.7 0.0 4.5 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KPA44463.1 - 0.0039 16.6 1.7 2.4 7.5 0.0 4.0 4 0 0 4 4 3 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KPA44463.1 - 0.0057 16.4 0.4 0.69 9.6 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 KPA44463.1 - 0.014 14.6 0.1 7.9 5.7 0.1 4.0 4 0 0 4 4 4 0 Zeta toxin Rad17 PF03215.15 KPA44463.1 - 0.048 13.6 0.1 6.7 6.6 0.0 3.6 4 0 0 4 4 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 KPA44463.1 - 0.16 11.8 0.6 46 3.9 0.0 4.0 4 0 0 4 4 3 0 NTPase Spuma_A9PTase PF03539.14 KPA44463.1 - 0.28 11.3 2.9 2.4 8.3 0.0 3.6 4 0 0 4 4 4 0 Spumavirus aspartic protease (A9) NACHT PF05729.12 KPA44463.1 - 1.7 8.5 6.7 31 4.4 0.0 4.5 5 0 0 5 5 3 0 NACHT domain Pil1 PF13805.6 KPA44463.1 - 2.5 7.5 21.0 0.022 14.3 0.5 2.7 2 0 0 2 2 1 0 Eisosome component PIL1 AAA_17 PF13207.6 KPA44463.1 - 2.6 8.5 4.4 1.5e+02 2.8 0.0 4.7 4 0 0 4 4 4 0 AAA domain CHAD PF05235.14 KPA44463.1 - 8.4 6.3 22.8 0.052 13.5 5.7 4.5 4 0 0 4 4 3 0 CHAD domain FAR1 PF03101.15 KPA44464.1 - 0.023 15.4 0.0 0.023 15.4 0.0 3.4 2 1 0 2 2 2 0 FAR1 DNA-binding domain zf-H2C2_2 PF13465.6 KPA44465.1 - 1.2 9.7 10.4 1 9.9 0.5 4.0 4 0 0 4 4 4 0 Zinc-finger double domain VASt PF16016.5 KPA44466.1 - 5.6e-37 127.5 0.0 9.6e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KPA44466.1 - 1.7e-23 82.7 0.0 2.7e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 GRAM domain CENP-Q PF13094.6 KPA44467.1 - 0.0011 19.3 7.9 0.0011 19.3 7.9 3.6 2 2 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Clr5 PF14420.6 KPA44467.1 - 0.0016 18.6 1.6 0.0021 18.2 0.2 2.0 2 0 0 2 2 2 1 Clr5 domain bZIP_1 PF00170.21 KPA44467.1 - 0.004 17.2 13.1 0.67 10.1 0.2 2.5 2 0 0 2 2 2 2 bZIP transcription factor Phage_GP20 PF06810.11 KPA44467.1 - 0.0065 16.3 8.7 0.11 12.3 3.7 2.5 2 0 0 2 2 2 1 Phage minor structural protein GP20 Med9 PF07544.13 KPA44467.1 - 0.059 13.5 7.4 0.66 10.1 4.5 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Sec20 PF03908.13 KPA44467.1 - 0.096 12.6 2.7 0.27 11.2 0.2 2.5 2 0 0 2 2 2 0 Sec20 STAT_alpha PF01017.20 KPA44467.1 - 0.18 11.7 4.9 0.95 9.3 4.8 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain BLOC1_2 PF10046.9 KPA44467.1 - 0.19 12.0 5.2 6.4 7.1 1.0 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec34 PF04136.15 KPA44467.1 - 0.21 11.5 6.9 0.23 11.3 0.2 2.8 3 0 0 3 3 3 0 Sec34-like family Snapin_Pallidin PF14712.6 KPA44467.1 - 0.25 11.8 9.3 0.44 11.0 0.5 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Prefoldin_2 PF01920.20 KPA44467.1 - 0.31 11.0 9.3 2.9 7.9 3.7 2.5 2 0 0 2 2 2 0 Prefoldin subunit OmpH PF03938.14 KPA44467.1 - 0.48 10.8 7.8 1.1 9.6 7.8 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TssO PF17561.2 KPA44467.1 - 0.5 10.5 2.9 1 9.5 0.5 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssO GAS PF13851.6 KPA44467.1 - 0.62 9.4 16.3 0.56 9.5 9.0 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.13 KPA44467.1 - 0.65 10.1 11.6 1.5 8.9 0.5 2.7 2 0 0 2 2 2 0 DivIVA protein KASH_CCD PF14662.6 KPA44467.1 - 0.68 9.7 11.8 2.2 8.1 11.9 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH KxDL PF10241.9 KPA44467.1 - 0.68 10.2 10.5 1.4 9.3 4.7 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein GIT_CC PF16559.5 KPA44467.1 - 0.69 9.8 6.2 6 6.8 0.2 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor PspA_IM30 PF04012.12 KPA44467.1 - 0.77 9.3 17.8 0.016 14.8 9.0 2.2 2 1 0 2 2 2 0 PspA/IM30 family Cnn_1N PF07989.11 KPA44467.1 - 0.87 9.8 11.6 1.5 9.0 0.3 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 LMBR1 PF04791.16 KPA44467.1 - 0.99 8.2 5.3 0.16 10.8 0.6 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein Fib_alpha PF08702.10 KPA44467.1 - 1 9.6 8.6 0.064 13.4 2.4 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 KPA44467.1 - 1.1 9.7 6.0 0.26 11.7 1.0 2.4 2 0 0 2 2 2 0 Syntaxin-like protein DUF4164 PF13747.6 KPA44467.1 - 1.3 9.4 13.5 0.43 10.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Ax_dynein_light PF10211.9 KPA44467.1 - 1.6 8.7 14.8 0.9 9.5 0.1 2.7 3 0 0 3 3 3 0 Axonemal dynein light chain DUF3837 PF12939.7 KPA44467.1 - 1.6 9.2 5.9 2 8.8 1.6 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF3837) SOGA PF11365.8 KPA44467.1 - 1.7 9.8 12.0 0.39 11.9 2.8 3.0 3 0 0 3 3 2 0 Protein SOGA Spc24 PF08286.11 KPA44467.1 - 3.5 7.9 12.0 2.5 8.4 0.1 2.8 3 0 0 3 3 2 0 Spc24 subunit of Ndc80 PRKG1_interact PF15898.5 KPA44467.1 - 3.6 8.5 17.0 0.056 14.4 7.5 2.6 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Rootletin PF15035.6 KPA44467.1 - 5.2 7.0 19.3 0.97 9.4 5.2 3.1 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 KPA44467.1 - 6.2 7.5 12.9 4.3 8.0 0.4 2.7 3 0 0 3 3 2 0 Initiation control protein YabA Lebercilin PF15619.6 KPA44467.1 - 6.2 6.4 17.1 0.34 10.6 0.2 2.6 3 0 0 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease Cep57_CLD PF14073.6 KPA44467.1 - 7.5 6.5 18.6 0.057 13.5 6.8 2.7 3 0 0 3 3 3 0 Centrosome localisation domain of Cep57 Cupin_8 PF13621.6 KPA44468.1 - 2.5e-34 119.2 0.0 2.8e-33 115.7 0.0 2.2 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 KPA44468.1 - 3.6e-06 26.7 0.1 0.00019 21.0 0.0 2.7 2 1 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 KPA44468.1 - 7.7e-05 23.1 0.0 0.00042 20.7 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KPA44468.1 - 0.046 13.4 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Cupin domain WD40 PF00400.32 KPA44469.1 - 9.4e-28 95.9 11.0 3.4e-06 27.7 1.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA44469.1 - 1.3e-08 35.0 0.2 0.059 13.7 0.0 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA44469.1 - 4.5e-05 22.3 10.6 2.2 6.8 0.1 5.0 2 2 3 5 5 5 5 Nucleoporin Nup120/160 SKA1 PF07160.12 KPA44469.1 - 0.0076 16.1 0.4 0.016 15.1 0.4 1.5 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF5046 PF16465.5 KPA44469.1 - 0.011 15.2 2.1 0.45 9.9 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5046) Vezatin PF12632.7 KPA44469.1 - 0.19 11.1 0.1 0.31 10.4 0.1 1.2 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes BCIP PF13862.6 KPA44471.1 - 1.3e-68 230.9 1.2 1.6e-68 230.6 1.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Ephrin_lbd PF01404.19 KPA44471.1 - 0.12 12.4 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain Vps5 PF09325.10 KPA44472.1 - 9e-12 45.0 0.5 1.6e-11 44.3 0.5 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KPA44472.1 - 1.4e-07 31.5 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.6 KPA44472.1 - 0.045 14.0 0.4 0.15 12.4 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ADH_N PF08240.12 KPA44473.1 - 3.3e-26 91.3 1.6 6.6e-26 90.3 1.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA44473.1 - 6.7e-16 58.4 0.0 1.2e-11 44.7 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPA44473.1 - 3.9e-08 33.0 0.9 0.00012 21.6 0.2 2.6 2 1 1 3 3 3 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KPA44473.1 - 0.0024 17.2 0.1 0.0043 16.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KPA44473.1 - 0.0036 16.9 0.4 0.0095 15.5 0.2 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 KPA44473.1 - 0.01 15.2 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 KPA44473.1 - 0.021 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KPA44473.1 - 0.031 14.5 0.3 0.094 13.0 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ADH_zinc_N_2 PF13602.6 KPA44473.1 - 0.032 15.3 0.0 0.066 14.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.21 KPA44473.1 - 0.046 13.8 0.5 0.09 12.8 0.1 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DAO PF01266.24 KPA44473.1 - 0.071 12.7 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPA44473.1 - 0.21 10.6 1.3 0.3 10.1 1.3 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KPA44473.1 - 0.27 11.1 0.6 0.44 10.4 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MitMem_reg PF13012.6 KPA44474.1 - 4.5e-09 36.7 0.0 9.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KPA44474.1 - 3.1e-08 33.6 0.0 5.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FCP1_C PF09309.10 KPA44474.1 - 0.71 9.7 6.0 0.57 10.0 4.4 1.6 2 0 0 2 2 2 0 FCP1, C-terminal Glyco_hydro_16 PF00722.21 KPA44475.1 - 2.4e-06 27.1 0.0 3.9e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_2 PF02210.24 KPA44475.1 - 0.09 13.4 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain MFS_1 PF07690.16 KPA44476.1 - 1.4e-16 60.4 42.2 1.4e-16 60.4 42.2 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3169 PF11368.8 KPA44476.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) OATP PF03137.20 KPA44476.1 - 1 7.6 17.5 0.017 13.4 5.7 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family RTA1 PF04479.13 KPA44477.1 - 1.5e-54 184.8 4.0 2.4e-54 184.1 4.0 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2530 PF10745.9 KPA44478.1 - 0.0051 17.0 0.2 0.045 14.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2530) MARVEL PF01284.23 KPA44478.1 - 0.012 15.6 7.3 0.021 14.8 6.7 1.6 1 1 1 2 2 2 0 Membrane-associating domain Mrx7 PF10906.8 KPA44478.1 - 0.014 15.7 0.1 0.031 14.5 0.1 1.7 1 0 0 1 1 1 0 MIOREX complex component 7 CrgA PF06781.12 KPA44478.1 - 0.044 13.8 2.5 8.5 6.5 0.3 3.1 2 1 1 3 3 3 0 Cell division protein CrgA DUF1129 PF06570.11 KPA44478.1 - 0.1 12.1 0.1 0.1 12.1 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4131 PF13567.6 KPA44478.1 - 1.7 8.3 4.5 1.9 8.1 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) FtsJ PF01728.19 KPA44479.1 - 4.4e-06 26.9 0.0 7.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF1168 PF06658.12 KPA44479.1 - 0.38 10.6 3.4 0.8 9.5 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Ppx-GppA PF02541.16 KPA44480.1 - 4.9e-44 150.9 0.0 1.4e-43 149.4 0.0 1.7 1 1 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 KPA44480.1 - 0.14 10.8 0.1 0.32 9.6 0.1 1.5 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family S-methyl_trans PF02574.16 KPA44482.1 - 1.1e-56 192.7 0.0 1.2e-56 192.5 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DAO PF01266.24 KPA44483.1 - 2e-47 162.5 0.3 2.3e-47 162.3 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPA44483.1 - 0.00032 20.9 0.1 0.00073 19.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPA44483.1 - 0.0018 18.8 0.0 0.021 15.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA44483.1 - 0.0019 17.5 0.0 0.16 11.2 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA44483.1 - 0.08 12.0 0.0 2.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KPA44483.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding adh_short PF00106.25 KPA44484.1 - 5.6e-43 146.7 0.3 6.7e-43 146.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA44484.1 - 3.8e-31 108.4 0.1 4.4e-31 108.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA44484.1 - 4.5e-12 46.2 0.1 1.1e-11 45.0 0.1 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KPA44484.1 - 0.0015 18.4 0.1 0.003 17.5 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding tRNA_m1G_MT PF01746.21 KPA44484.1 - 0.0062 16.3 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Epimerase PF01370.21 KPA44484.1 - 0.0099 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPA44484.1 - 0.015 14.7 0.0 0.027 13.9 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase CBFD_NFYB_HMF PF00808.23 KPA44485.1 - 1.3e-17 63.8 0.7 1.3e-17 63.8 0.7 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KPA44485.1 - 0.00014 22.2 0.3 0.00039 20.8 0.1 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KPA44485.1 - 0.043 13.8 0.1 0.12 12.4 0.0 1.7 1 1 1 2 2 2 0 Bromodomain associated SIR2 PF02146.17 KPA44486.1 - 1.3e-54 184.9 0.0 1.9e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family PEP_mutase PF13714.6 KPA44486.1 - 0.51 9.8 2.2 4.7 6.6 0.7 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Cu-oxidase_3 PF07732.15 KPA44487.1 - 1.9e-45 153.7 4.4 4.9e-43 145.9 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KPA44487.1 - 2.3e-38 131.0 8.0 1e-34 119.2 2.9 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KPA44487.1 - 1.1e-33 116.7 0.1 1.8e-31 109.4 0.0 2.8 3 0 0 3 3 3 2 Multicopper oxidase Romo1 PF10247.9 KPA44488.1 - 8.6e-29 99.7 15.0 1.1e-28 99.3 15.0 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KPA44488.1 - 0.0084 16.5 2.8 0.01 16.2 2.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LapA_dom PF06305.11 KPA44488.1 - 0.43 10.4 1.0 9.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain FHA PF00498.26 KPA44489.1 - 1.9e-17 63.3 0.1 5.9e-17 61.8 0.1 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KPA44489.1 - 5.6e-05 23.4 0.0 0.00021 21.5 0.0 2.0 2 0 0 2 2 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF812 PF05667.11 KPA44489.1 - 0.00063 18.8 8.3 0.00094 18.2 8.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) YhfZ_C PF14503.6 KPA44489.1 - 0.0055 16.3 0.1 0.0055 16.3 0.1 2.1 2 0 0 2 2 2 1 YhfZ C-terminal domain GAS PF13851.6 KPA44489.1 - 0.007 15.7 12.1 0.021 14.2 3.8 2.5 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Spc29 PF17082.5 KPA44489.1 - 0.21 11.4 8.7 0.11 12.3 1.6 2.4 1 1 1 2 2 2 0 Spindle Pole Component 29 EzrA PF06160.12 KPA44489.1 - 0.35 9.0 11.4 0.57 8.3 11.4 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3452 PF11934.8 KPA44489.1 - 0.75 9.4 1.8 5 6.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) DUF4407 PF14362.6 KPA44489.1 - 1.1 8.5 16.5 2.7 7.3 16.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KPA44489.1 - 1.2 9.4 8.1 7.6 6.7 7.7 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family MetOD2 PF18548.1 KPA44489.1 - 1.3 9.2 8.6 0.24 11.5 0.3 3.0 2 1 1 3 3 3 0 Metanogen output domain 2 Vps51 PF08700.11 KPA44489.1 - 1.3 9.2 8.5 0.68 10.1 0.7 3.2 3 0 0 3 3 3 0 Vps51/Vps67 Jnk-SapK_ap_N PF09744.9 KPA44489.1 - 1.7 8.8 22.0 1.1 9.4 10.7 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 EAP30 PF04157.16 KPA44489.1 - 2.1 7.6 9.8 0.3 10.3 3.9 2.3 2 0 0 2 2 2 0 EAP30/Vps36 family V_ATPase_I PF01496.19 KPA44489.1 - 2.1 6.2 8.4 3.8 5.3 8.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 KPA44489.1 - 2.7 7.1 10.0 4.3 6.5 0.6 2.2 2 0 0 2 2 2 0 TMPIT-like protein DUF4201 PF13870.6 KPA44489.1 - 3.7 7.2 14.6 0.99 9.1 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 KPA44489.1 - 3.8 7.6 9.3 2.6 8.1 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Med9 PF07544.13 KPA44489.1 - 4 7.6 8.1 2.4 8.3 0.6 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3450 PF11932.8 KPA44489.1 - 4.1 6.6 17.9 0.45 9.8 9.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 KPA44489.1 - 7.4 6.6 12.7 0.27 11.2 2.6 2.5 2 0 0 2 2 2 0 Prefoldin subunit CENP-H PF05837.12 KPA44489.1 - 8.2 6.9 17.0 0.64 10.5 5.3 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Ax_dynein_light PF10211.9 KPA44489.1 - 8.8 6.2 15.1 0.3 11.0 5.2 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain RTA1 PF04479.13 KPA44492.1 - 6.6e-41 140.2 5.1 8.7e-41 139.8 5.1 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3112 PF11309.8 KPA44492.1 - 0.2 11.1 4.0 0.18 11.3 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) DUF4131 PF13567.6 KPA44492.1 - 0.94 9.1 3.2 0.83 9.3 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Tetraspanin PF00335.20 KPA44492.1 - 1.1 9.0 6.1 1.5 8.5 0.2 2.1 2 0 0 2 2 2 0 Tetraspanin family Zn_clus PF00172.18 KPA44493.1 - 5e-07 29.7 7.4 5e-07 29.7 7.4 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA44493.1 - 4.4e-05 22.6 0.4 7.1e-05 22.0 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.26 KPA44494.1 - 2.7e-91 307.0 9.3 3.7e-91 306.5 9.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KPA44494.1 - 0.0027 18.0 0.0 0.0065 16.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) CENP-F_leu_zip PF10473.9 KPA44495.1 - 4e-06 26.9 29.9 4e-06 26.9 29.9 9.6 2 1 4 8 8 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 KPA44495.1 - 0.00014 21.9 8.7 0.00014 21.9 8.7 14.4 6 5 7 14 14 14 1 Centrosome localisation domain of PPC89 Spc7 PF08317.11 KPA44495.1 - 0.00037 19.5 195.1 0.0023 16.9 24.0 9.8 1 1 10 11 11 11 8 Spc7 kinetochore protein MscS_porin PF12795.7 KPA44495.1 - 7.9 6.0 185.7 0.05 13.1 18.1 8.1 1 1 6 7 7 7 0 Mechanosensitive ion channel porin domain Importin_rep_6 PF18829.1 KPA44496.1 - 5 7.3 6.4 1.4 9.1 0.1 2.6 2 0 0 2 2 2 0 Importin repeat 6 PTPA PF03095.15 KPA44497.1 - 5.8e-119 397.0 0.0 6.7e-119 396.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF3636 PF12331.8 KPA44498.1 - 0.066 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) Abhydrolase_3 PF07859.13 KPA44499.1 - 0.00033 20.6 0.0 0.00062 19.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KPA44499.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Ion_trans_2 PF07885.16 KPA44500.1 - 9.9e-36 121.6 23.9 9.1e-21 73.6 5.3 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KPA44500.1 - 1.1e-05 24.8 9.4 0.0006 19.1 0.0 2.8 2 1 0 2 2 2 2 Ion transport protein CPP1-like PF11833.8 KPA44500.1 - 4.4 6.9 9.6 1.4 8.5 0.8 3.1 2 1 2 4 4 4 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like zf-RING_4 PF14570.6 KPA44501.1 - 5.1e-20 71.0 12.4 1.1e-19 69.9 12.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KPA44501.1 - 6.1e-08 32.4 0.0 1.7e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KPA44501.1 - 5.1e-07 29.5 7.6 5.1e-07 29.5 7.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KPA44501.1 - 0.00016 21.2 3.1 0.00016 21.2 3.1 5.2 5 1 0 5 5 3 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KPA44501.1 - 0.00023 21.4 10.1 0.0006 20.1 10.1 1.7 1 0 0 1 1 1 1 Ring finger domain CDC27 PF09507.10 KPA44501.1 - 0.0029 17.1 8.9 0.0029 17.1 8.9 5.7 5 1 1 7 7 4 1 DNA polymerase subunit Cdc27 Prok-RING_4 PF14447.6 KPA44501.1 - 0.0045 16.8 9.0 0.2 11.5 9.5 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 SET_assoc PF11767.8 KPA44501.1 - 0.013 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Baculo_IE-1 PF05290.11 KPA44501.1 - 0.062 13.3 4.8 0.1 12.6 4.8 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 KPA44501.1 - 0.21 11.7 4.7 0.58 10.3 4.7 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE PF01363.21 KPA44501.1 - 2.3 8.4 11.6 0.081 13.1 4.4 2.1 2 0 0 2 2 2 0 FYVE zinc finger Complex1_30kDa PF00329.19 KPA44502.1 - 3.1e-44 150.5 0.0 4.3e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Voltage_CLC PF00654.20 KPA44504.1 - 0.15 11.3 3.2 0.27 10.4 3.2 1.3 1 0 0 1 1 1 0 Voltage gated chloride channel Zds_C PF08632.10 KPA44505.1 - 1.1e-29 101.9 1.2 2e-29 101.1 1.2 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2433 PF10360.9 KPA44506.1 - 2.3e-49 166.6 0.0 3.8e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 KPA44506.1 - 0.00018 22.0 0.0 0.00059 20.4 0.0 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPA44506.1 - 0.0068 16.6 0.0 0.019 15.2 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ubie_methyltran PF01209.18 KPA44507.1 - 3.9e-77 258.7 0.0 5.4e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KPA44507.1 - 3.4e-14 53.3 0.0 6.4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA44507.1 - 2.2e-11 44.2 0.0 4.6e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA44507.1 - 4.4e-11 42.8 0.0 6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA44507.1 - 5e-09 36.8 0.0 8.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA44507.1 - 1.1e-06 28.6 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KPA44507.1 - 0.084 12.7 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase ADH_zinc_N PF00107.26 KPA44507.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase E1_dh PF00676.20 KPA44508.1 - 3.4e-88 295.5 0.0 4.2e-88 295.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KPA44508.1 - 0.0038 17.0 0.5 0.087 12.6 0.1 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SidC_N PF18219.1 KPA44508.1 - 0.027 13.5 0.1 0.038 13.0 0.1 1.1 1 0 0 1 1 1 0 SidC N-terminal domain DXP_synthase_N PF13292.6 KPA44508.1 - 0.036 13.3 0.4 0.18 11.0 0.0 2.1 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase ProQ PF04352.13 KPA44508.1 - 0.086 12.7 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 ProQ/FINO family HECT PF00632.25 KPA44509.1 - 2.3e-76 257.2 0.0 3.5e-76 256.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KPA44509.1 - 0.0013 18.7 8.7 1.9 8.6 0.1 6.5 6 1 1 7 7 7 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KPA44509.1 - 0.019 14.5 0.1 0.087 12.4 0.0 2.0 2 0 0 2 2 2 0 CLASP N terminal HEAT PF02985.22 KPA44509.1 - 0.025 14.8 3.3 0.72 10.3 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat DUF1833 PF08875.11 KPA44509.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) HEAT_EZ PF13513.6 KPA44509.1 - 0.07 13.7 4.7 0.42 11.2 0.1 3.9 4 0 0 4 4 4 0 HEAT-like repeat MMS19_N PF14500.6 KPA44509.1 - 0.11 12.0 1.6 1.8 8.1 0.1 3.3 2 2 2 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II Sec3_C PF09763.9 KPA44511.1 - 3.7e-228 759.4 0.1 4.7e-228 759.1 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KPA44511.1 - 8.5e-29 99.5 0.0 1.9e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 KPA44511.1 - 0.002 18.4 0.3 0.0068 16.7 0.0 2.0 2 0 0 2 2 2 1 Sec3 exocyst complex subunit Vps52 PF04129.12 KPA44511.1 - 0.043 12.5 0.6 0.093 11.5 0.6 1.5 1 0 0 1 1 1 0 Vps52 / Sac2 family DUF2018 PF09442.10 KPA44511.1 - 0.11 13.5 0.1 0.48 11.4 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) Fe-ADH PF00465.19 KPA44512.1 - 3.1e-103 345.4 0.0 3.9e-103 345.1 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KPA44512.1 - 4.6e-15 56.0 0.0 3.1e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 KPA44512.1 - 0.0041 16.8 0.1 0.0069 16.1 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Vps23_core PF09454.10 KPA44512.1 - 0.19 11.7 0.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Vps23 core domain ThrE PF06738.12 KPA44513.1 - 1.9e-66 223.9 24.0 1.9e-63 214.1 4.3 2.4 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KPA44513.1 - 5.9e-13 49.1 10.0 5.9e-13 49.1 10.0 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE Hexapep PF00132.24 KPA44515.1 - 1e-09 37.7 6.3 1.7e-05 24.3 1.7 4.4 4 1 1 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KPA44515.1 - 2.4e-05 24.0 6.7 0.13 12.1 0.4 4.5 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Complex1_51K PF01512.17 KPA44516.1 - 1.4e-47 161.4 0.0 2.3e-47 160.7 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KPA44516.1 - 4.3e-29 100.4 0.3 4.3e-29 100.4 0.3 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KPA44516.1 - 3.3e-09 36.5 0.1 1.1e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 SLBB domain PEX11 PF05648.14 KPA44517.1 - 2.8e-24 85.8 0.0 7.9e-24 84.4 0.0 1.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) CUE PF02845.16 KPA44519.1 - 0.00011 21.8 0.1 0.00021 20.9 0.1 1.5 1 0 0 1 1 1 1 CUE domain Smr PF01713.21 KPA44519.1 - 0.00069 19.9 0.1 0.0019 18.5 0.1 1.7 1 0 0 1 1 1 1 Smr domain NPC1_N PF16414.5 KPA44520.1 - 1.9e-83 279.8 6.7 2.6e-83 279.3 6.7 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KPA44520.1 - 9.9e-75 252.2 5.9 1e-44 152.9 0.0 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KPA44520.1 - 7.5e-50 168.7 4.6 7.5e-50 168.7 4.6 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 KPA44520.1 - 0.0016 18.3 0.2 0.0037 17.2 0.2 1.6 1 0 0 1 1 1 1 Folate receptor family MMPL PF03176.15 KPA44520.1 - 0.0044 16.0 43.0 0.0072 15.3 14.4 3.0 2 2 0 2 2 2 2 MMPL family ACR_tran PF00873.19 KPA44520.1 - 1.6 6.3 19.2 0.31 8.6 11.4 2.1 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Mannosyl_trans2 PF04188.13 KPA44521.1 - 4.7e-52 177.8 4.3 7.2e-52 177.2 4.3 1.3 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) Abhydrolase_2 PF02230.16 KPA44522.1 - 5.1e-28 98.4 0.0 7.2e-17 61.9 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KPA44522.1 - 2.3e-10 40.3 0.0 6.8e-10 38.8 0.0 1.6 1 1 1 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 KPA44522.1 - 1.3e-07 31.5 0.0 4.5e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 KPA44522.1 - 3.1e-06 26.9 0.0 5e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KPA44522.1 - 1.9e-05 24.6 0.0 4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA44522.1 - 0.00014 22.5 0.0 0.00025 21.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA44522.1 - 0.0021 17.4 1.4 1.6 7.9 0.0 2.7 2 1 0 3 3 3 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 KPA44522.1 - 0.005 16.8 0.0 0.0076 16.2 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.28 KPA44522.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Esterase PF00756.20 KPA44522.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.5 1 1 1 2 2 2 0 Putative esterase Abhydrolase_1 PF00561.20 KPA44522.1 - 0.027 14.1 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KPA44522.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) MR_MLE_C PF13378.6 KPA44523.1 - 6.3e-58 195.9 0.0 2.3e-57 194.1 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KPA44523.1 - 0.00058 20.0 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KPA44523.1 - 0.0075 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Phg_2220_C PF09524.10 KPA44524.1 - 0.22 11.6 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) Rad10 PF03834.14 KPA44525.1 - 6.2e-48 161.6 0.0 8.4e-48 161.1 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Myc_N PF01056.18 KPA44525.1 - 0.0025 17.8 1.2 0.0038 17.2 1.2 1.3 1 0 0 1 1 1 1 Myc amino-terminal region UIM PF02809.20 KPA44525.1 - 0.021 14.7 2.1 0.021 14.7 2.1 3.0 3 0 0 3 3 3 0 Ubiquitin interaction motif DUF913 PF06025.12 KPA44525.1 - 0.11 11.5 0.8 0.14 11.2 0.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DNA_pol_alpha_N PF12254.8 KPA44526.1 - 0.062 13.4 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Lactamase_B_2 PF12706.7 KPA44527.1 - 4.6e-31 107.9 0.1 5.3e-30 104.4 0.1 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KPA44527.1 - 2.1e-10 40.7 0.0 6.7e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KPA44527.1 - 0.021 14.8 3.9 0.078 13.0 2.7 2.5 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Ndc80_HEC PF03801.13 KPA44528.1 - 6.4e-59 198.0 0.8 1.2e-58 197.1 0.8 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Spc7 PF08317.11 KPA44528.1 - 0.00045 19.2 35.0 0.00077 18.4 12.8 3.1 3 0 0 3 3 3 2 Spc7 kinetochore protein DUF2935 PF11155.8 KPA44528.1 - 0.014 15.7 0.1 0.27 11.5 0.0 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF2935) DUF1664 PF07889.12 KPA44528.1 - 0.042 13.9 0.6 0.042 13.9 0.6 4.6 3 2 3 6 6 5 0 Protein of unknown function (DUF1664) FliJ PF02050.16 KPA44528.1 - 0.17 12.2 28.5 0.14 12.3 2.6 3.4 2 1 1 3 3 3 0 Flagellar FliJ protein Fungal_TACC PF12709.7 KPA44528.1 - 0.25 11.8 0.1 0.25 11.8 0.1 5.4 4 1 2 6 6 6 0 Fungal Transforming acidic coiled-coil (TACC) proteins AAA_13 PF13166.6 KPA44528.1 - 1.3 7.5 28.6 0.41 9.2 6.8 3.0 3 0 0 3 3 3 0 AAA domain Gp-FAR-1 PF05823.12 KPA44528.1 - 1.4 9.3 14.8 0.4 11.0 1.9 3.2 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TPR_MLP1_2 PF07926.12 KPA44528.1 - 1.4 8.9 43.5 0.023 14.8 17.7 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 KPA44528.1 - 2.7 7.6 34.6 1.7 8.2 8.6 3.6 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease HALZ PF02183.18 KPA44528.1 - 3.6 7.9 12.8 0.31 11.3 0.9 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper FliD_C PF07195.12 KPA44528.1 - 3.7 6.9 13.5 3.4 7.0 3.0 3.2 2 1 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus LRS4 PF10422.9 KPA44528.1 - 3.8 7.0 15.7 0.094 12.3 2.4 2.4 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 PepSY_TM_like_2 PF16357.5 KPA44528.1 - 5.5 6.9 0.0 5.5 6.9 0.0 3.4 3 1 1 4 4 4 0 Putative PepSY_TM-like Pex14_N PF04695.13 KPA44529.1 - 4.1e-36 125.0 4.8 4.1e-36 125.0 4.8 3.4 2 2 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.9 KPA44529.1 - 0.00031 21.1 4.6 0.00031 21.1 4.6 1.8 2 0 0 2 2 1 1 Zinc finger-containing protein CR6_interact PF10147.9 KPA44529.1 - 0.00046 20.0 0.1 0.00082 19.1 0.1 1.4 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF3584 PF12128.8 KPA44529.1 - 0.0011 16.6 7.7 0.0014 16.2 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF1043 PF06295.12 KPA44529.1 - 0.0027 17.7 2.8 0.0064 16.5 2.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1043) HLH PF00010.26 KPA44529.1 - 0.0033 17.3 0.4 10 6.2 0.0 3.3 2 1 1 3 3 3 0 Helix-loop-helix DNA-binding domain Prominin PF05478.11 KPA44529.1 - 0.0047 15.0 1.0 0.0061 14.6 1.0 1.1 1 0 0 1 1 1 1 Prominin Spc7 PF08317.11 KPA44529.1 - 0.0055 15.6 4.8 0.0088 15.0 4.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Golgin_A5 PF09787.9 KPA44529.1 - 0.027 13.9 7.8 0.045 13.2 7.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 AAA_13 PF13166.6 KPA44529.1 - 0.045 12.4 2.7 0.059 12.0 2.7 1.2 1 0 0 1 1 1 0 AAA domain HMMR_N PF15905.5 KPA44529.1 - 0.05 13.1 7.6 0.095 12.2 7.6 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 KPA44529.1 - 0.076 13.1 4.3 0.12 12.5 4.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 KPA44529.1 - 0.11 11.4 0.3 0.14 11.0 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Baculo_PEP_C PF04513.12 KPA44529.1 - 0.14 12.2 7.6 1 9.4 0.5 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-SNARE PF05008.15 KPA44529.1 - 0.15 12.4 4.0 6.9 7.1 0.5 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF848 PF05852.11 KPA44529.1 - 0.15 12.1 6.8 0.26 11.4 6.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Fez1 PF06818.15 KPA44529.1 - 0.16 12.4 4.3 0.26 11.7 4.3 1.4 1 0 0 1 1 1 0 Fez1 SlyX PF04102.12 KPA44529.1 - 0.22 12.2 2.8 0.56 10.9 1.7 2.4 1 1 1 2 2 1 0 SlyX Csm1_N PF18504.1 KPA44529.1 - 0.67 10.3 8.4 0.48 10.8 4.1 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF1664 PF07889.12 KPA44529.1 - 1.3 9.1 4.7 3 7.9 4.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TSC22 PF01166.18 KPA44529.1 - 1.5 9.2 3.8 39 4.7 0.5 2.9 2 1 0 2 2 2 0 TSC-22/dip/bun family 5_nucleotid PF05761.14 KPA44529.1 - 1.9 7.3 3.5 2.6 6.8 3.5 1.1 1 0 0 1 1 1 0 5' nucleotidase family TMPIT PF07851.13 KPA44529.1 - 2.1 7.5 4.2 3.5 6.8 4.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein Cytochrom_B562 PF07361.11 KPA44529.1 - 2.5 8.8 7.3 0.55 10.9 2.8 2.3 1 1 1 2 2 2 0 Cytochrome b562 ABC_tran_CTD PF16326.5 KPA44529.1 - 3.3 8.0 9.6 2.1 8.6 3.4 3.0 1 1 2 3 3 3 0 ABC transporter C-terminal domain CdvA PF18822.1 KPA44529.1 - 3.3 7.5 9.6 3.5 7.5 3.3 2.6 1 1 1 2 2 2 0 CdvA-like coiled-coil domain ERM PF00769.19 KPA44529.1 - 4 7.2 14.5 5.5 6.7 14.5 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Pollen_allerg_2 PF01620.16 KPA44529.1 - 7.5 6.7 18.6 0.087 13.0 9.1 2.3 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) Abhydrolase_3 PF07859.13 KPA44530.1 - 4.9e-46 157.3 0.0 2.9e-45 154.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPA44530.1 - 0.00041 19.3 0.1 0.0098 14.8 0.0 2.2 2 0 0 2 2 2 2 Steryl acetyl hydrolase FAD_binding_4 PF01565.23 KPA44531.1 - 1.4e-15 57.3 0.0 2.2e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phasin_2 PF09361.10 KPA44531.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Phasin protein HMG_CoA_synt_C PF08540.10 KPA44532.1 - 6e-104 347.6 1.0 7.6e-104 347.3 1.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KPA44532.1 - 4e-94 313.4 0.2 7.2e-94 312.5 0.2 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Tic110 PF16940.5 KPA44532.1 - 0.037 12.5 0.0 0.06 11.8 0.0 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter BCS1_N PF08740.11 KPA44533.1 - 8.1e-55 185.7 0.4 8.1e-55 185.7 0.4 2.1 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KPA44533.1 - 2.8e-18 66.6 0.0 1.1e-09 38.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPA44533.1 - 0.0003 20.6 0.0 0.00057 19.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ABC_membrane PF00664.23 KPA44533.1 - 0.0014 18.3 2.7 0.0024 17.6 2.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF815 PF05673.13 KPA44533.1 - 0.0031 16.7 0.0 0.006 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KPA44533.1 - 0.0031 17.5 0.0 0.0096 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KPA44533.1 - 0.006 16.2 0.0 0.015 14.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA44533.1 - 0.0067 16.8 0.3 0.02 15.3 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain ATPase PF06745.13 KPA44533.1 - 0.047 13.0 0.6 0.091 12.1 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.6 KPA44533.1 - 0.056 13.2 8.5 4.3 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_B PF00430.18 KPA44533.1 - 0.12 12.5 14.7 0.35 11.0 14.7 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) AAA_18 PF13238.6 KPA44533.1 - 0.36 11.4 0.0 0.36 11.4 0.0 3.0 2 1 0 2 2 1 0 AAA domain DUF3807 PF12720.7 KPA44533.1 - 6.1 7.1 22.6 11 6.2 22.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF1682 PF07946.14 KPA44533.1 - 9.4 5.3 20.7 19 4.3 20.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) WD40 PF00400.32 KPA44537.1 - 3.3e-25 87.9 15.8 7.4e-06 26.6 0.1 6.9 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA44537.1 - 5.1e-12 45.9 5.7 0.00013 22.2 0.0 4.6 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KPA44537.1 - 0.00068 19.6 9.3 0.099 12.6 0.2 3.7 2 2 0 2 2 2 2 Transcription factor IIIC subunit delta N-term SGL PF08450.12 KPA44538.1 - 0.0017 18.0 0.1 0.071 12.7 0.0 2.3 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KPA44538.1 - 0.0051 16.8 0.1 1.3 9.2 0.0 4.3 5 0 0 5 5 5 1 NHL repeat GSDH PF07995.11 KPA44538.1 - 0.011 15.1 4.4 1.1 8.5 3.0 3.2 3 1 0 3 3 3 0 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 KPA44538.1 - 0.033 14.4 0.1 0.31 11.4 0.0 2.7 2 0 0 2 2 2 0 Two component regulator propeller DUF1604 PF07713.13 KPA44539.1 - 5.1e-41 138.4 2.4 5.1e-41 138.4 2.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KPA44539.1 - 3.7e-06 26.7 1.2 3.7e-05 23.5 0.5 2.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KPA44539.1 - 0.0026 17.8 3.2 0.0052 16.9 0.2 3.1 3 0 0 3 3 3 1 G-patch domain Pkinase PF00069.25 KPA44540.1 - 5.4e-70 235.8 0.0 1e-69 234.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA44540.1 - 3.4e-41 141.2 0.0 1.1e-40 139.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KPA44540.1 - 9e-20 70.2 0.1 1.5e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KPA44540.1 - 6.5e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KPA44540.1 - 1e-05 25.0 0.3 1.9e-05 24.1 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KPA44540.1 - 0.00013 21.0 11.0 0.00074 18.6 11.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KPA44540.1 - 0.0044 17.0 0.0 0.0044 17.0 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family WaaY PF06176.11 KPA44540.1 - 0.0087 15.7 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KPA44540.1 - 0.048 13.2 0.1 0.048 13.2 0.1 2.4 3 0 0 3 3 3 0 RIO1 family YrbL-PhoP_reg PF10707.9 KPA44540.1 - 0.095 12.2 0.0 0.095 12.2 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Rcd1 PF04078.13 KPA44541.1 - 1.4e-125 417.9 4.9 1.6e-125 417.6 4.9 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like CIA30 PF08547.12 KPA44542.1 - 1e-33 116.6 0.1 1.2e-33 116.4 0.1 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) GST_N PF02798.20 KPA44544.1 - 4.8e-12 46.0 0.0 8e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPA44544.1 - 2.7e-08 33.9 0.0 4.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPA44544.1 - 8.6e-08 32.4 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPA44544.1 - 4.8e-07 29.7 0.0 7.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPA44544.1 - 3.8e-06 27.2 0.0 6.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPA44544.1 - 0.00019 21.6 0.0 0.00031 20.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FBPase PF00316.20 KPA44545.1 - 1.9e-69 233.0 0.0 2.5e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain PEX11 PF05648.14 KPA44546.1 - 5.7e-66 222.2 0.5 6.4e-66 222.0 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) RRM_1 PF00076.22 KPA44547.1 - 1.4e-24 85.7 0.0 3.2e-11 42.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPA44547.1 - 0.0064 16.3 0.0 1.4 8.9 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif PXA PF02194.15 KPA44548.1 - 2.1e-53 181.0 0.2 2.1e-53 181.0 0.2 2.6 4 0 0 4 4 4 1 PXA domain Nexin_C PF08628.12 KPA44548.1 - 5.7e-30 104.2 0.1 2.5e-29 102.1 0.1 2.2 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KPA44548.1 - 1.3e-21 76.7 0.7 3.7e-21 75.2 0.7 1.8 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KPA44548.1 - 3.1e-11 43.6 0.2 1.3e-10 41.6 0.2 2.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Methyltransf_4 PF02390.17 KPA44549.1 - 6.3e-57 191.8 0.0 8.4e-57 191.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KPA44549.1 - 0.00012 22.7 0.0 0.00028 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA44549.1 - 0.00018 22.2 0.0 0.00047 20.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KPA44549.1 - 0.0012 18.8 0.0 0.0019 18.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA44549.1 - 0.0017 18.0 0.0 0.0044 16.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KPA44549.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 KPA44549.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KPA44549.1 - 0.052 14.2 0.0 0.18 12.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KPA44549.1 - 0.089 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 CMAS PF02353.20 KPA44549.1 - 0.13 11.5 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KPA44549.1 - 0.19 11.4 0.0 0.48 10.2 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Homoserine_dh PF00742.19 KPA44551.1 - 2.4e-52 177.4 0.0 3.3e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KPA44551.1 - 1.3e-19 70.9 0.0 2.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.6 KPA44552.1 - 2.4e-28 98.3 18.0 2.4e-28 98.3 18.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) bZIP_2 PF07716.15 KPA44553.1 - 5.9e-07 29.5 9.0 1.3e-06 28.3 9.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KPA44553.1 - 1.2e-06 28.5 5.3 2.6e-06 27.4 5.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KPA44553.1 - 6.4 7.4 8.6 0.28 11.7 2.2 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Glyco_hydro_76 PF03663.14 KPA44554.1 - 4.7e-156 519.9 5.6 5.5e-156 519.7 5.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KPA44554.1 - 0.032 13.3 11.4 0.81 8.7 0.6 3.1 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 DUF3602 PF12223.8 KPA44555.1 - 6e-19 68.4 6.5 6.2e-15 55.6 1.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) P33MONOX PF15302.6 KPA44555.1 - 0.17 11.6 3.1 0.2 11.3 3.1 1.1 1 0 0 1 1 1 0 P33 mono-oxygenase Actin PF00022.19 KPA44556.1 - 3.7e-126 421.0 0.0 1.5e-125 419.0 0.0 1.7 1 1 0 1 1 1 1 Actin Ank_2 PF12796.7 KPA44557.1 - 3.8e-13 49.8 1.7 2.2e-05 24.9 0.5 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA44557.1 - 1.2e-08 35.3 0.9 0.0042 17.6 0.5 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KPA44557.1 - 1.7e-08 34.6 0.5 0.0012 19.2 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KPA44557.1 - 3.4e-08 33.6 0.7 0.00039 20.7 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA44557.1 - 1e-07 31.7 0.1 0.055 14.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 KPA44557.1 - 8e-07 28.9 1.2 6.1e-06 26.0 0.1 2.7 2 1 0 2 2 2 1 KilA-N domain HYLS1_C PF15311.6 KPA44559.1 - 0.39 11.5 4.9 1.3 9.8 4.9 2.0 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus V_ATPase_I PF01496.19 KPA44559.1 - 2.4 6.0 13.7 3.4 5.5 13.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KPA44559.1 - 6.2 6.3 18.6 10 5.5 18.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 KPA44560.1 - 2.3e-72 243.5 0.0 4.1e-72 242.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA44560.1 - 6.2e-50 169.9 0.0 1e-49 169.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPA44560.1 - 9.9e-05 21.3 0.0 0.0002 20.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase CLASP_N PF12348.8 KPA44560.1 - 0.032 13.8 1.0 0.31 10.6 0.4 2.2 2 0 0 2 2 2 0 CLASP N terminal Kinase-like PF14531.6 KPA44560.1 - 0.048 13.0 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Kinase-like RTTN_N PF14726.6 KPA44560.1 - 0.39 11.5 1.6 4.9 8.0 0.5 2.6 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Mur_ligase_M PF08245.12 KPA44562.1 - 3.7e-06 27.1 0.3 1e-05 25.6 0.3 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KPA44562.1 - 0.047 13.9 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain PNKP-ligase_C PF16536.5 KPA44562.1 - 0.099 12.9 0.1 3 8.2 0.0 2.7 2 0 0 2 2 2 0 PNKP adenylyltransferase domain, C-terminal region PA28_alpha PF02251.18 KPA44562.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Seryl_tRNA_N PF02403.22 KPA44562.1 - 7.1 6.9 8.5 1.1 9.5 2.6 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF218 PF02698.17 KPA44563.1 - 0.00016 21.7 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Abhydrolase_6 PF12697.7 KPA44564.1 - 0.00034 21.3 0.9 0.00051 20.7 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPA44564.1 - 0.0085 15.6 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family PhoPQ_related PF10142.9 KPA44564.1 - 0.22 10.1 0.1 0.34 9.5 0.1 1.4 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein ICE2 PF08426.10 KPA44565.1 - 6.4e-157 522.8 6.5 7.3e-157 522.6 6.5 1.0 1 0 0 1 1 1 1 ICE2 Aa_trans PF01490.18 KPA44566.1 - 5.5e-28 97.8 30.7 6.4e-28 97.6 30.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FA_desaturase PF00487.24 KPA44567.1 - 7.3e-27 94.8 15.1 7.3e-27 94.8 15.1 1.7 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 KPA44567.1 - 4.8e-19 67.6 0.3 9.9e-19 66.6 0.1 1.7 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.26 KPA44568.1 - 9.9e-24 83.3 0.2 2e-23 82.3 0.2 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KPA44568.1 - 0.0029 17.8 0.2 0.0094 16.1 0.0 1.9 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF883 PF05957.13 KPA44568.1 - 0.062 13.9 0.8 0.3 11.7 0.8 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ATG_C PF09333.11 KPA44568.1 - 0.29 11.5 2.0 1.4 9.3 2.0 2.0 1 1 0 1 1 1 0 Autophagy-related protein C terminal domain Cas_Cas02710 PF09670.10 KPA44569.1 - 0.016 14.0 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) ATPgrasp_Ter PF15632.6 KPA44569.1 - 0.064 13.0 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon HSA PF07529.13 KPA44569.1 - 0.088 13.1 0.3 0.49 10.8 0.2 2.1 2 0 0 2 2 2 0 HSA Peptidase_M24_C PF16188.5 KPA44569.1 - 0.13 12.3 0.2 0.4 10.8 0.2 1.8 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 UBX PF00789.20 KPA44570.1 - 3.5e-07 30.3 0.4 1.3e-06 28.5 0.1 2.2 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 KPA44570.1 - 0.0079 16.1 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2 PF00096.26 KPA44570.1 - 0.09 13.3 0.8 0.17 12.4 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2HE PF16278.5 KPA44570.1 - 0.093 13.2 0.1 0.093 13.2 0.1 2.8 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger SOBP PF15279.6 KPA44570.1 - 0.98 10.0 5.5 1.3 9.6 5.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Ribosomal_60s PF00428.19 KPA44571.1 - 4.3e-27 94.5 11.5 5.2e-27 94.3 11.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage_holin_6_1 PF09682.10 KPA44571.1 - 0.22 11.9 0.3 0.22 11.9 0.3 1.9 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF2408 PF10303.9 KPA44572.1 - 4.5e-41 140.6 5.3 5.8e-28 98.1 0.2 5.0 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 KPA44572.1 - 5 7.6 7.4 3.4 8.2 0.2 3.9 4 1 1 5 5 5 0 Snapin/Pallidin YCII PF03795.14 KPA44573.1 - 4e-08 33.6 0.0 5.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain DUF5134 PF17197.4 KPA44574.1 - 0.02 14.8 0.9 0.045 13.7 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) RDD PF06271.12 KPA44574.1 - 0.035 14.3 0.2 0.035 14.3 0.2 2.5 3 1 0 3 3 3 0 RDD family DUF1345 PF07077.11 KPA44574.1 - 0.22 11.2 2.3 0.22 11.2 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) DUF3262 PF11660.8 KPA44574.1 - 3.8 8.0 8.5 0.2 12.1 0.5 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3262) AC_N PF16214.5 KPA44576.1 - 0.23 10.6 0.5 0.29 10.2 0.5 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region AMP-binding PF00501.28 KPA44577.1 - 3.2e-84 283.0 0.0 4.7e-84 282.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA44577.1 - 3.5e-18 66.3 0.3 8.2e-18 65.2 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KPA44577.1 - 3.2e-06 26.3 0.0 0.00015 20.8 0.0 2.7 3 0 0 3 3 3 1 GH3 auxin-responsive promoter RTX_C PF08339.10 KPA44577.1 - 0.0096 16.0 0.0 0.061 13.4 0.0 2.1 1 1 1 2 2 2 1 RTX C-terminal domain Hox9_act PF04617.13 KPA44577.1 - 0.13 13.0 0.6 0.23 12.2 0.6 1.3 1 0 0 1 1 1 0 Hox9 activation region FCH PF00611.23 KPA44578.1 - 1.6e-23 82.8 0.1 1.6e-23 82.8 0.1 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KPA44578.1 - 1.5e-21 75.9 3.1 2.1e-12 46.7 0.1 2.7 3 0 0 3 3 3 2 Variant SH3 domain C1_1 PF00130.22 KPA44578.1 - 4.4e-15 55.3 4.2 7e-15 54.7 4.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 KPA44578.1 - 3.1e-14 52.3 0.1 6.6e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KPA44578.1 - 3.6e-05 23.4 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 KPA44578.1 - 0.00033 20.9 0.7 0.18 12.1 0.2 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain C1_2 PF03107.16 KPA44578.1 - 0.0057 16.9 4.0 0.01 16.1 4.0 1.4 1 0 0 1 1 1 1 C1 domain SH3_10 PF17902.1 KPA44578.1 - 0.035 14.2 0.0 1.1 9.4 0.0 2.9 2 0 0 2 2 2 0 SH3 domain FYVE PF01363.21 KPA44578.1 - 0.12 12.5 2.1 0.26 11.5 2.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger 7TM_GPCR_Sri PF10327.9 KPA44578.1 - 0.23 10.6 0.1 0.36 10.0 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri LETM1 PF07766.13 KPA44578.1 - 1.9 7.8 6.8 0.35 10.2 0.2 2.2 2 0 0 2 2 2 0 LETM1-like protein OrfB_Zn_ribbon PF07282.11 KPA44578.1 - 3.5 7.6 5.2 11 6.1 5.2 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2H2 PF00096.26 KPA44579.1 - 2.4e-05 24.5 14.8 0.46 11.1 2.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KPA44579.1 - 0.0035 17.5 0.4 0.031 14.4 0.0 2.3 2 1 0 2 2 2 1 Aberrant zinc-finger SHE3 PF17078.5 KPA44579.1 - 0.0036 17.1 5.8 0.0036 17.1 5.8 1.4 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 ZapB PF06005.12 KPA44579.1 - 0.021 15.3 3.6 0.051 14.0 3.6 1.6 1 0 0 1 1 1 0 Cell division protein ZapB HOOK PF05622.12 KPA44579.1 - 0.022 12.9 4.0 0.029 12.5 4.0 1.1 1 0 0 1 1 1 0 HOOK protein Tho2 PF11262.8 KPA44579.1 - 0.055 12.7 0.7 0.079 12.2 0.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 GAS PF13851.6 KPA44579.1 - 0.057 12.8 5.0 0.098 12.0 5.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-C2H2_4 PF13894.6 KPA44579.1 - 0.059 14.2 11.7 8 7.6 1.5 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPA44579.1 - 0.087 13.3 15.6 6.1 7.5 0.5 3.7 3 1 0 3 3 3 0 Zinc-finger double domain Seryl_tRNA_N PF02403.22 KPA44579.1 - 0.14 12.4 3.2 0.28 11.4 3.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.18 KPA44579.1 - 0.16 12.3 4.9 0.1 13.0 2.0 2.2 2 1 1 3 3 2 0 TSC-22/dip/bun family bZIP_2 PF07716.15 KPA44579.1 - 0.3 11.2 5.5 0.24 11.5 3.2 2.1 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 KPA44579.1 - 0.98 9.2 6.5 1.5 8.6 5.7 1.7 1 1 0 1 1 1 0 Septum formation initiator 3-dmu-9_3-mt PF06983.13 KPA44581.1 - 1e-39 135.6 0.4 1.3e-39 135.3 0.4 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase GATase PF00117.28 KPA44582.1 - 4.8e-36 124.3 0.0 7.9e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KPA44582.1 - 3.1e-35 120.1 0.0 5.7e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KPA44582.1 - 3.4e-08 32.9 0.0 3e-05 23.3 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KPA44582.1 - 1.6e-06 28.0 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KPA44582.1 - 0.0044 15.9 0.1 0.0087 14.9 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 KPA44582.1 - 0.011 15.3 0.0 0.066 12.7 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 KPA44582.1 - 0.038 14.0 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 KPA44582.1 - 0.051 12.9 0.1 0.097 11.9 0.1 1.4 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 KPA44582.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 PP-loop family ThiI PF02568.14 KPA44582.1 - 0.17 11.5 0.0 0.43 10.1 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) MFS_1 PF07690.16 KPA44583.1 - 8.5e-30 103.9 31.9 8.5e-30 103.9 31.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily BRI3BP PF14965.6 KPA44583.1 - 0.0083 15.7 1.3 0.023 14.2 1.3 1.7 1 0 0 1 1 1 1 Negative regulator of p53/TP53 DEC-1_N PF04625.13 KPA44584.1 - 0.8 8.6 5.9 0.51 9.3 0.7 2.3 1 1 0 2 2 2 0 DEC-1 protein, N-terminal region DUF4185 PF13810.6 KPA44584.1 - 0.87 8.8 10.6 0.28 10.4 0.1 3.6 3 1 0 4 4 4 0 Domain of unknown function (DUF4185) MRP-L20 PF12824.7 KPA44586.1 - 1.4e-48 165.1 5.3 1.8e-48 164.8 5.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KPA44586.1 - 0.00037 20.6 0.0 0.00061 19.9 0.0 1.4 1 1 0 1 1 1 1 Neugrin HTH_11 PF08279.12 KPA44586.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 HTH domain RasGAP PF00616.19 KPA44588.1 - 1.6e-30 106.4 0.4 1.5e-21 77.1 0.0 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KPA44588.1 - 0.00022 21.4 0.0 0.0007 19.8 0.0 1.9 1 1 0 1 1 1 1 C2 domain Pro_isomerase PF00160.21 KPA44589.1 - 1.8e-47 161.5 0.0 2.8e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KPA44589.1 - 2.3e-05 24.1 8.9 0.0066 16.5 1.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KPA44589.1 - 0.0008 19.5 1.9 0.0035 17.4 1.9 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KPA44589.1 - 0.0046 16.7 6.4 0.059 13.2 1.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA44589.1 - 0.012 15.7 0.3 0.051 13.8 0.3 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPA44589.1 - 0.025 15.2 9.8 0.044 14.4 6.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPA44589.1 - 0.42 11.6 3.9 1.7 9.7 0.4 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KPA44589.1 - 0.42 10.9 3.0 5 7.5 1.9 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.16 KPA44590.1 - 3.3e-41 141.2 0.3 1.5e-33 116.3 0.0 2.0 1 1 1 2 2 2 2 D-Tyr-tRNA(Tyr) deacylase Tail_tube PF10618.9 KPA44590.1 - 0.046 13.6 0.0 0.091 12.7 0.0 1.5 2 0 0 2 2 2 0 Phage tail tube protein Not3 PF04065.15 KPA44591.1 - 7.5e-90 300.4 22.5 1.2e-89 299.7 22.5 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KPA44591.1 - 8.5e-43 145.6 5.1 8.5e-43 145.6 5.1 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF1192 PF06698.11 KPA44591.1 - 0.014 15.4 3.8 0.025 14.6 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Syntaxin_2 PF14523.6 KPA44591.1 - 0.031 14.6 1.2 0.031 14.6 1.2 2.9 3 0 0 3 3 3 0 Syntaxin-like protein DUF2373 PF10180.9 KPA44591.1 - 0.043 13.7 2.9 0.098 12.5 2.9 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.13 KPA44591.1 - 0.13 12.8 10.6 0.18 12.3 0.5 3.4 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CENP-Q PF13094.6 KPA44591.1 - 0.2 11.8 21.8 0.22 11.7 8.9 2.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CorA PF01544.18 KPA44591.1 - 0.27 10.5 4.6 0.12 11.7 1.0 2.0 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Sec5 PF15469.6 KPA44591.1 - 1.4 8.7 9.0 0.9 9.3 0.6 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF1465 PF07323.12 KPA44591.1 - 2.4 8.0 8.5 1.4 8.7 1.7 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1465) 4HB_MCP_1 PF12729.7 KPA44591.1 - 6.4 6.3 13.2 2.5 7.6 6.6 2.3 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DivIC PF04977.15 KPA44591.1 - 9.4 6.1 8.2 5.6 6.8 1.2 3.0 2 0 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 KPA44591.1 - 9.8 6.7 8.2 12 6.4 0.6 3.3 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) FOXP-CC PF16159.5 KPA44593.1 - 0.00026 21.5 4.7 0.18 12.4 0.0 3.2 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 KPA44593.1 - 0.06 13.8 0.3 0.06 13.8 0.3 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA44593.1 - 9.3 7.4 21.2 6.5 7.9 0.1 4.5 3 1 1 4 4 4 0 C2H2-type zinc finger Filament PF00038.21 KPA44596.1 - 0.00019 21.2 22.5 0.00019 21.2 22.5 4.9 3 1 2 5 5 5 1 Intermediate filament protein ATG16 PF08614.11 KPA44596.1 - 0.00063 20.0 7.5 0.00063 20.0 7.5 6.0 3 2 1 4 4 3 1 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KPA44596.1 - 0.004 16.5 10.8 0.004 16.5 10.8 4.1 1 1 3 5 5 4 3 Domain of unknown function (DUF4407) GIT_CC PF16559.5 KPA44596.1 - 0.0075 16.1 3.6 0.0075 16.1 3.6 6.9 6 1 1 7 7 7 1 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 KPA44596.1 - 0.012 15.6 10.5 0.012 15.6 10.5 3.9 4 2 0 5 5 5 0 Protein of unknown function (DUF1664) HOOK PF05622.12 KPA44596.1 - 0.075 11.2 58.4 0.01 14.0 29.7 3.4 2 1 1 3 3 3 0 HOOK protein Bacillus_HBL PF05791.11 KPA44596.1 - 0.14 11.9 16.7 0.75 9.6 0.2 4.4 1 1 3 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) Hemagglutinin PF00509.18 KPA44596.1 - 0.17 10.3 4.9 0.3 9.4 4.9 1.4 1 0 0 1 1 1 0 Haemagglutinin NPV_P10 PF05531.12 KPA44596.1 - 0.92 10.0 18.2 11 6.5 0.0 5.2 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 KPA44596.1 - 3.1 8.1 0.0 0.15 12.3 6.0 7.6 5 1 1 6 6 5 0 ABC transporter C-terminal domain Baculo_F PF12259.8 KPA44596.1 - 4.9 5.6 5.7 9.8 4.6 5.7 1.5 1 0 0 1 1 1 0 Baculovirus F protein WD40 PF00400.32 KPA44597.1 - 6.4e-15 55.3 13.1 0.0024 18.7 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA44597.1 - 0.00037 20.7 0.0 0.92 9.8 0.0 4.8 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KPA44597.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain Glyco_transf_8 PF01501.20 KPA44599.1 - 1.7e-11 44.1 0.0 2.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 ATG2_CAD PF13329.6 KPA44600.1 - 1.7e-50 170.8 0.4 3.4e-50 169.8 0.4 1.6 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KPA44600.1 - 5.1e-30 103.7 0.3 6.8e-29 100.1 0.0 3.1 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 KPA44600.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Amino_oxidase PF01593.24 KPA44601.1 - 5.5e-48 164.4 0.0 1.5e-47 163.0 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA44601.1 - 4.5e-15 55.6 0.0 8.2e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA44601.1 - 6.5e-07 28.9 0.1 1.5e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA44601.1 - 1.7e-05 23.7 0.3 0.00048 18.9 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KPA44601.1 - 2.6e-05 24.0 0.0 0.0002 21.0 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPA44601.1 - 4e-05 23.7 0.1 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KPA44601.1 - 5e-05 22.6 0.2 0.00011 21.5 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KPA44601.1 - 0.00011 22.7 1.2 0.00017 22.1 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA44601.1 - 0.00016 21.0 0.0 0.00029 20.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KPA44601.1 - 0.00047 19.5 0.3 0.00077 18.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KPA44601.1 - 0.0017 17.8 0.5 0.0027 17.1 0.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KPA44601.1 - 0.0022 17.9 0.1 0.0047 16.8 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KPA44601.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KPA44601.1 - 0.041 13.0 0.2 0.069 12.2 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPA44601.1 - 0.049 12.9 0.5 0.17 11.1 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA44601.1 - 0.075 12.1 0.3 0.12 11.3 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Acyl-CoA_dh_1 PF00441.24 KPA44602.1 - 3.1e-35 121.6 0.4 6.3e-35 120.6 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KPA44602.1 - 1.4e-19 70.0 0.0 3.1e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KPA44602.1 - 8e-19 67.6 0.4 1.4e-18 66.9 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPA44602.1 - 2e-09 38.1 0.1 4.3e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KPA44602.1 - 4.6e-07 30.2 0.0 1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-CCHC PF00098.23 KPA44603.1 - 2.4e-52 172.7 67.1 3.1e-09 36.5 2.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KPA44603.1 - 9.2e-12 44.5 41.6 0.1 12.3 0.5 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KPA44603.1 - 7.2e-09 35.5 51.0 0.061 13.3 0.5 7.1 2 2 5 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.6 KPA44603.1 - 7e-08 32.2 49.5 0.0073 16.1 1.6 6.9 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 KPA44603.1 - 0.00036 20.2 42.1 0.57 9.9 1.4 7.0 5 2 2 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KPA44603.1 - 0.0033 17.2 1.5 0.0033 17.2 1.5 7.1 7 1 0 7 7 7 2 Zinc knuckle Beta-lactamase PF00144.24 KPA44604.1 - 4.6e-26 91.9 0.2 7.4e-26 91.2 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase BTRD1 PF17660.1 KPA44604.1 - 9.5e-21 73.4 0.7 6.2e-09 35.5 0.0 3.7 3 0 0 3 3 3 3 Bacterial tandem repeat domain 1 SLAC1 PF03595.17 KPA44605.1 - 1e-88 297.7 48.0 1.2e-88 297.6 48.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HET PF06985.11 KPA44606.1 - 5.5e-24 85.2 0.0 1e-23 84.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NUDIX_4 PF14815.6 KPA44607.1 - 3.7e-22 78.4 0.1 7.2e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 KPA44607.1 - 7.5e-19 68.2 0.0 1.5e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KPA44607.1 - 3.6e-05 23.4 0.0 8.1e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SAE2 PF08573.10 KPA44608.1 - 3.1e-36 124.9 0.9 3.1e-36 124.9 0.9 4.0 3 1 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Prp19 PF08606.11 KPA44608.1 - 0.32 11.0 2.6 0.83 9.7 2.6 1.7 1 0 0 1 1 1 0 Prp19/Pso4-like DUF1664 PF07889.12 KPA44608.1 - 0.44 10.6 4.0 12 5.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) UCH PF00443.29 KPA44609.1 - 8.6e-46 156.5 0.0 1.4e-45 155.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPA44609.1 - 1.9e-10 40.9 0.0 6.6e-09 35.8 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCR_14kD PF02271.16 KPA44610.1 - 3.6e-43 145.6 1.3 4.1e-43 145.4 1.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ferritin PF00210.24 KPA44610.1 - 0.038 13.9 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like domain Mito_carr PF00153.27 KPA44611.1 - 2.2e-63 210.2 3.7 7.2e-22 77.1 0.1 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein AhpC-TSA PF00578.21 KPA44612.1 - 6.2e-25 87.5 0.0 8.9e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPA44612.1 - 1.2e-15 57.5 0.0 2.1e-15 56.7 0.0 1.3 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KPA44612.1 - 0.0003 20.9 0.0 0.0017 18.4 0.0 2.0 2 1 1 3 3 3 1 AhpC/TSA antioxidant enzyme DUF1180 PF06679.12 KPA44612.1 - 0.15 12.5 0.8 0.23 11.9 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CI-B14_5a PF07347.12 KPA44613.1 - 0.053 13.4 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Yae1_N PF09811.9 KPA44614.1 - 3.4e-09 36.2 4.0 5.1e-09 35.7 4.0 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal adh_short_C2 PF13561.6 KPA44615.1 - 1.2e-50 172.3 0.9 1.8e-42 145.5 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA44615.1 - 4.5e-45 153.5 0.1 6.1e-45 153.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA44615.1 - 2.1e-15 57.1 0.1 2.8e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA44615.1 - 6.6e-05 22.5 0.1 0.00046 19.7 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Acetyltransf_1 PF00583.25 KPA44616.1 - 2.5e-11 43.8 0.0 3.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KPA44616.1 - 4.2e-07 29.8 0.1 7.9e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KPA44616.1 - 8.5e-07 29.0 0.1 1.3e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA44616.1 - 8.9e-06 26.0 0.0 2.2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPA44616.1 - 0.022 14.8 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MIP-T3_C PF17749.1 KPA44617.1 - 0.028 14.4 3.8 0.049 13.6 3.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Topoisom_I_N PF02919.15 KPA44617.1 - 0.028 13.9 1.6 0.045 13.2 1.6 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF4407 PF14362.6 KPA44617.1 - 5.9 6.2 6.5 9.4 5.5 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IF-2B PF01008.17 KPA44618.1 - 1.3e-47 162.4 0.2 5.9e-47 160.2 0.2 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 KPA44618.1 - 0.045 13.7 0.1 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain NIF PF03031.18 KPA44619.1 - 4.7e-55 185.6 0.0 6.3e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1761 PF08570.10 KPA44620.1 - 1.1e-26 93.5 2.1 1.3e-26 93.3 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) BRCT_assoc PF12820.7 KPA44620.1 - 0.063 13.1 0.0 0.081 12.7 0.0 1.1 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT Ribosomal_L7Ae PF01248.26 KPA44621.1 - 6.6e-22 77.1 0.4 2.9e-21 75.0 0.4 2.1 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ComGG PF14173.6 KPA44621.1 - 0.024 15.1 0.0 0.98 9.9 0.0 2.4 2 0 0 2 2 2 0 ComG operon protein 7 FAM60A PF15396.6 KPA44621.1 - 5.9 6.8 9.0 1.6 8.7 5.9 1.6 2 0 0 2 2 2 0 Protein Family FAM60A DNA_pol_phi PF04931.13 KPA44621.1 - 6.9 4.6 12.9 0.15 10.1 6.5 1.6 2 0 0 2 2 2 0 DNA polymerase phi UcrQ PF02939.16 KPA44622.1 - 9.2e-35 118.4 0.8 1.1e-34 118.2 0.8 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.25 KPA44623.1 - 3.4e-25 89.1 5.8 6.1e-25 88.2 5.8 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KPA44623.1 - 0.0009 18.4 5.7 0.0012 18.0 5.7 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF676 PF05057.14 KPA44625.1 - 5.6e-55 186.2 0.0 8.1e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KPA44625.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KPA44625.1 - 0.0025 17.6 0.0 0.095 12.4 0.0 2.3 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KPA44625.1 - 0.0044 17.7 0.0 0.062 13.9 0.0 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KPA44625.1 - 0.023 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PRELI PF04707.14 KPA44626.1 - 4.7e-21 75.2 0.2 1.5e-17 63.9 0.0 2.2 1 1 1 2 2 2 2 PRELI-like family MFS_1 PF07690.16 KPA44627.1 - 2.7e-33 115.3 27.3 5.1e-33 114.4 27.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyoxalase PF00903.25 KPA44628.1 - 1.2e-06 28.8 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KPA44628.1 - 0.0014 19.4 0.0 0.0021 18.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Pkinase PF00069.25 KPA44629.1 - 7.4e-63 212.4 0.0 1e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LMWPc PF01451.21 KPA44629.1 - 1.8e-39 135.4 0.0 3.2e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase_Tyr PF07714.17 KPA44629.1 - 3e-27 95.6 0.0 4.7e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPA44629.1 - 0.023 13.6 0.0 0.05 12.5 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KPA44629.1 - 0.049 13.0 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPA44629.1 - 0.083 12.8 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family CKAP2_C PF15297.6 KPA44630.1 - 0.037 13.1 0.1 0.062 12.4 0.1 1.3 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus TFIIA PF03153.13 KPA44630.1 - 0.15 12.1 3.8 0.18 11.8 3.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 KPA44630.1 - 1.6 8.7 9.7 0.15 12.1 3.2 2.2 2 1 0 2 2 2 0 RXT2-like, N-terminal Nop14 PF04147.12 KPA44630.1 - 2.5 6.2 9.6 4 5.5 9.6 1.2 1 0 0 1 1 1 0 Nop14-like family Hexapep PF00132.24 KPA44631.1 - 1.5e-09 37.2 5.3 5.2e-05 22.8 1.8 4.9 3 2 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KPA44631.1 - 1.2e-06 28.2 0.2 0.0075 16.0 0.0 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KPA44631.1 - 0.07 12.1 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase DUF3455 PF11937.8 KPA44632.1 - 2.8e-29 102.5 0.0 3.5e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) MFS_1 PF07690.16 KPA44633.1 - 3.1e-36 125.1 21.7 3.1e-36 125.1 21.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPA44633.1 - 1.7e-05 24.3 0.3 1.7e-05 24.3 0.3 2.8 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB DUF4202 PF13875.6 KPA44634.1 - 4e-77 258.3 0.2 4.5e-77 258.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) FGF-BP1 PF06473.12 KPA44635.1 - 2.1 8.1 33.8 0.46 10.3 8.0 3.2 2 1 1 3 3 3 0 FGF binding protein 1 (FGF-BP1) 14-3-3 PF00244.20 KPA44636.1 - 6.3e-07 29.1 0.0 9.7e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 14-3-3 protein Sterol-sensing PF12349.8 KPA44637.1 - 4.9e-35 120.6 8.0 9.8e-35 119.6 8.0 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KPA44637.1 - 2e-07 29.6 5.3 3.1e-07 28.9 5.3 1.2 1 0 0 1 1 1 1 Patched family Cupin_8 PF13621.6 KPA44638.1 - 3.1e-67 227.0 0.1 3.6e-67 226.7 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KPA44638.1 - 2.9e-06 27.0 0.0 0.0017 17.9 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KPA44638.1 - 0.015 15.8 0.0 0.3 11.5 0.0 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase Spb1_C PF07780.12 KPA44639.1 - 2.3e-85 285.5 22.3 2.3e-85 285.5 22.3 3.3 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KPA44639.1 - 1.4e-55 188.2 0.0 2.6e-55 187.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KPA44639.1 - 1.8e-50 170.9 9.1 1.8e-50 170.9 9.1 5.1 3 1 2 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KPA44639.1 - 0.068 13.0 0.0 0.25 11.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Dynamin_N PF00350.23 KPA44640.1 - 7.6e-44 149.7 0.0 1.7e-43 148.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KPA44640.1 - 5.6e-13 48.8 3.2 3.5e-11 42.8 0.3 2.7 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.23 KPA44640.1 - 2.4e-05 24.4 0.0 0.00024 21.2 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF4872 PF16169.5 KPA44640.1 - 0.0087 15.8 0.6 0.047 13.4 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4872) AAA_21 PF13304.6 KPA44640.1 - 0.041 13.7 1.4 0.086 12.6 0.0 2.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system SRI PF08236.11 KPA44640.1 - 0.092 12.9 0.3 0.41 10.9 0.1 2.2 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain AAA_15 PF13175.6 KPA44640.1 - 0.11 12.2 0.9 0.22 11.2 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 KPA44640.1 - 0.15 12.5 3.5 0.21 11.9 0.1 3.0 3 1 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 KPA44640.1 - 0.18 12.0 0.2 0.7 10.1 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cation_efflux PF01545.21 KPA44641.1 - 1.1e-12 48.1 13.4 1.5e-12 47.6 13.4 1.1 1 0 0 1 1 1 1 Cation efflux family Ferrochelatase PF00762.19 KPA44641.1 - 0.061 12.4 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Ferrochelatase DUF5056 PF16479.5 KPA44641.1 - 1.6 9.0 3.4 18 5.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) PIG-Y PF15159.6 KPA44642.1 - 1.3e-22 80.5 8.4 2.1e-22 79.8 8.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y zf-MYND PF01753.18 KPA44643.1 - 2.8e-07 30.5 20.6 2.8e-07 30.5 20.6 2.0 2 0 0 2 2 2 1 MYND finger zf-TAZ PF02135.16 KPA44643.1 - 0.36 11.3 8.5 0.71 10.4 8.5 1.4 1 0 0 1 1 1 0 TAZ zinc finger SR-25 PF10500.9 KPA44643.1 - 1.1 8.9 14.5 2.3 7.8 14.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ebp2 PF05890.12 KPA44644.1 - 8.7e-96 320.6 12.8 8.7e-96 320.6 12.8 2.3 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 CDC27 PF09507.10 KPA44644.1 - 4 6.7 42.4 0.019 14.4 24.2 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Cyanate_lyase PF02560.14 KPA44645.1 - 6e-32 109.3 0.0 9e-32 108.7 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KPA44645.1 - 0.00088 19.6 0.0 0.0012 19.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KPA44645.1 - 0.034 13.9 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KPA44645.1 - 0.051 13.3 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.22 KPA44645.1 - 0.1 12.6 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Myb_DNA-binding PF00249.31 KPA44645.1 - 0.16 12.2 0.0 30 4.9 0.0 2.8 4 0 0 4 4 4 0 Myb-like DNA-binding domain MPLKIP PF15502.6 KPA44647.1 - 0.036 14.3 0.4 0.036 14.3 0.4 2.2 2 0 0 2 2 2 0 M-phase-specific PLK1-interacting protein B-block_TFIIIC PF04182.12 KPA44648.1 - 4e-12 46.1 0.0 8.8e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC zf-BED PF02892.15 KPA44648.1 - 0.11 12.5 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 BED zinc finger PHD_2 PF13831.6 KPA44648.1 - 1.2 8.8 2.9 14 5.4 0.2 2.4 2 0 0 2 2 2 0 PHD-finger UQ_con PF00179.26 KPA44649.1 - 4.5e-19 68.5 0.0 8.2e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KPA44649.1 - 0.04 14.2 0.0 0.089 13.1 0.0 1.6 1 0 0 1 1 1 0 RWD domain P5-ATPase PF12409.8 KPA44651.1 - 3e-39 134.0 0.0 6.7e-39 132.8 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KPA44651.1 - 2.5e-28 98.8 0.4 6.5e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KPA44651.1 - 3.4e-15 56.9 0.1 9.3e-09 35.9 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KPA44651.1 - 8.5e-08 32.1 7.4 2.6e-07 30.5 7.4 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KPA44651.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) NAP PF00956.18 KPA44652.1 - 9.2e-103 343.1 4.9 1.1e-102 342.9 4.9 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Striatin PF08232.12 KPA44652.1 - 0.16 12.5 2.8 0.19 12.3 0.5 2.0 2 0 0 2 2 2 0 Striatin family ANAPC15 PF15243.6 KPA44652.1 - 6.3 7.3 10.4 1.9 9.0 3.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 DUF4611 PF15387.6 KPA44652.1 - 6.4 7.1 8.8 9.6 6.5 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) 2-Hacid_dh_C PF02826.19 KPA44653.1 - 9.8e-52 174.9 0.0 1.5e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPA44653.1 - 3.3e-35 120.6 0.1 4.4e-35 120.2 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KPA44653.1 - 7.3e-05 23.0 0.4 0.00028 21.1 0.1 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KPA44653.1 - 0.0027 17.3 0.1 0.023 14.3 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KPA44653.1 - 0.005 16.9 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 KPA44653.1 - 0.0052 16.5 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 ACT domain XdhC_C PF13478.6 KPA44653.1 - 0.036 14.6 0.0 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Amdase PF17645.1 KPA44653.1 - 0.091 12.4 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Arylmalonate decarboxylase Myosin_head PF00063.21 KPA44654.1 - 1.6e-261 869.3 0.1 2.3e-261 868.9 0.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KPA44654.1 - 2.1e-26 92.2 2.8 2.1e-26 92.2 2.8 2.6 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KPA44654.1 - 2e-14 52.0 31.9 0.0001 21.8 1.1 6.2 6 0 0 6 6 5 4 IQ calmodulin-binding motif AAA_22 PF13401.6 KPA44654.1 - 0.0028 17.9 0.1 0.012 15.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain Flagellin_N PF00669.20 KPA44654.1 - 0.0048 17.0 5.9 0.014 15.5 5.5 2.0 1 1 0 1 1 1 1 Bacterial flagellin N-terminal helical region DUF812 PF05667.11 KPA44654.1 - 0.01 14.8 24.9 0.017 14.0 24.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 KPA44654.1 - 0.017 14.5 26.1 0.024 14.0 12.2 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_16 PF13191.6 KPA44654.1 - 0.031 14.7 0.4 0.14 12.5 0.0 2.4 2 0 0 2 2 1 0 AAA ATPase domain Sec34 PF04136.15 KPA44654.1 - 0.035 14.0 3.6 0.043 13.7 1.7 2.2 1 1 1 2 2 2 0 Sec34-like family PhoH PF02562.16 KPA44654.1 - 0.057 12.9 1.6 6.5 6.2 0.0 4.4 6 0 0 6 6 6 0 PhoH-like protein Flp_N PF03930.14 KPA44654.1 - 0.067 13.2 0.7 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus Myosin_N PF02736.19 KPA44654.1 - 0.11 12.4 1.4 0.31 10.9 0.2 2.2 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Baculo_PEP_C PF04513.12 KPA44654.1 - 0.15 12.1 2.2 0.62 10.1 2.2 2.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SOGA PF11365.8 KPA44654.1 - 0.62 11.2 14.6 0.54 11.4 0.4 3.8 3 0 0 3 3 3 0 Protein SOGA FUSC PF04632.12 KPA44654.1 - 0.76 8.2 5.2 1.4 7.4 5.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_GP20 PF06810.11 KPA44654.1 - 0.83 9.5 13.9 0.21 11.4 5.1 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF3450 PF11932.8 KPA44654.1 - 0.99 8.7 21.9 5.7 6.2 11.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ABC_tran PF00005.27 KPA44654.1 - 1.5 9.4 0.0 1.5 9.4 0.0 2.8 3 1 0 3 3 1 0 ABC transporter KASH_CCD PF14662.6 KPA44654.1 - 2.3 8.0 26.3 2.5 7.9 7.5 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 KPA44654.1 - 5 7.3 26.4 0.093 13.0 7.6 3.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Noelin-1 PF12308.8 KPA44654.1 - 5.2 7.1 7.2 0.49 10.4 1.2 2.4 2 0 0 2 2 2 0 Neurogenesis glycoprotein Laminin_II PF06009.12 KPA44654.1 - 5.6 7.0 15.1 4 7.5 2.3 2.7 1 1 1 2 2 2 0 Laminin Domain II ADIP PF11559.8 KPA44654.1 - 7.3 6.7 22.9 1.8 8.6 5.2 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KPA44654.1 - 7.4 6.6 27.2 3 7.9 9.7 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 KPA44654.1 - 8.5 6.5 23.0 11 6.1 10.3 3.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase AAA_18 PF13238.6 KPA44655.1 - 6.2e-28 97.9 0.6 3.5e-27 95.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KPA44655.1 - 2e-08 34.7 0.0 8.7e-08 32.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 KPA44655.1 - 3.6e-06 27.4 0.0 0.00054 20.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 KPA44655.1 - 5.6e-06 26.5 0.0 0.0027 17.8 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.6 KPA44655.1 - 1.9e-05 24.9 0.0 0.0045 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KPA44655.1 - 4.5e-05 23.8 0.0 0.00018 21.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KPA44655.1 - 0.00019 21.2 0.1 0.56 9.9 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase dNK PF01712.19 KPA44655.1 - 0.00025 20.9 0.7 0.24 11.2 0.1 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase NTPase_1 PF03266.15 KPA44655.1 - 0.00072 19.5 0.1 0.0017 18.3 0.1 1.6 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.6 KPA44655.1 - 0.0016 18.7 0.2 0.0027 18.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 KPA44655.1 - 0.0021 18.4 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain SKI PF01202.22 KPA44655.1 - 0.0039 17.3 0.2 0.049 13.8 0.2 2.0 1 1 0 1 1 1 1 Shikimate kinase AAA_16 PF13191.6 KPA44655.1 - 0.0046 17.4 0.1 0.0071 16.7 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KPA44655.1 - 0.0069 15.9 0.0 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 KPA44655.1 - 0.013 15.3 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KPA44655.1 - 0.016 14.9 0.0 0.055 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KPA44655.1 - 0.018 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.6 KPA44655.1 - 0.026 14.6 0.0 0.089 12.9 0.0 1.9 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_19 PF13245.6 KPA44655.1 - 0.027 14.8 0.2 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KPA44655.1 - 0.033 13.9 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KPA44655.1 - 0.047 14.1 0.0 0.093 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SRP54 PF00448.22 KPA44655.1 - 0.054 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KPA44655.1 - 0.065 13.0 0.1 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein GTP_EFTU PF00009.27 KPA44655.1 - 0.076 12.5 0.1 0.91 9.0 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Rad17 PF03215.15 KPA44655.1 - 0.087 12.7 0.1 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain MeaB PF03308.16 KPA44655.1 - 0.09 11.7 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KPA44655.1 - 0.12 12.1 1.3 1.3 8.7 0.4 2.3 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KPA44655.1 - 0.17 11.1 0.1 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_3 PF07726.11 KPA44655.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KPA44655.1 - 0.2 10.9 0.7 0.32 10.3 0.1 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family RuvB_N PF05496.12 KPA44655.1 - 0.22 11.2 0.2 0.64 9.7 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Ham1p_like PF01725.16 KPA44656.1 - 8.6e-57 192.1 0.0 9.6e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_C78 PF07910.13 KPA44657.1 - 5.5e-70 235.1 0.0 7.5e-70 234.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Arm PF00514.23 KPA44657.1 - 0.06 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat zf-Di19 PF05605.12 KPA44657.1 - 0.091 13.1 0.9 0.38 11.1 0.1 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ras PF00071.22 KPA44658.1 - 1e-44 152.0 0.0 1.2e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA44658.1 - 3.9e-16 59.4 0.0 5.4e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA44658.1 - 5.3e-06 26.0 0.0 5.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPA44658.1 - 1e-05 25.2 0.0 5.5e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KPA44658.1 - 0.0001 22.3 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KPA44658.1 - 0.00084 18.8 0.0 0.0019 17.6 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KPA44658.1 - 0.0056 16.6 0.1 0.87 9.5 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KPA44658.1 - 0.015 14.9 0.0 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.6 KPA44658.1 - 0.088 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain WAPL PF07814.13 KPA44659.1 - 1.3e-60 205.2 3.8 1.7e-60 204.8 3.8 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 KPA44660.1 - 1.2e-79 266.6 0.0 2.8e-79 265.4 0.0 1.5 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KPA44660.1 - 0.00073 19.1 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Elf1 PF05129.13 KPA44661.1 - 1.6e-29 101.8 0.2 1.9e-29 101.5 0.2 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Vps36-NZF-N PF16988.5 KPA44661.1 - 0.012 15.0 0.2 0.018 14.4 0.2 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PHD_4 PF16866.5 KPA44661.1 - 0.013 15.6 0.2 0.016 15.3 0.2 1.3 1 0 0 1 1 1 0 PHD-finger Cys_rich_CPXG PF14255.6 KPA44661.1 - 0.031 14.2 0.8 0.059 13.3 0.8 1.5 1 0 0 1 1 1 0 Cysteine-rich CPXCG zf-Sec23_Sec24 PF04810.15 KPA44661.1 - 0.055 13.5 1.6 0.55 10.3 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger GTP_CH_N PF12471.8 KPA44662.1 - 3.1e-87 291.3 0.0 4.2e-87 290.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KPA44662.1 - 1.2e-14 54.2 0.0 2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II CTP_transf_like PF01467.26 KPA44664.1 - 4.2e-07 30.3 0.0 8.9e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like Glu-tRNAGln PF02686.15 KPA44664.1 - 0.025 14.9 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit MarC PF01914.17 KPA44664.1 - 0.22 10.9 0.1 0.35 10.2 0.1 1.2 1 0 0 1 1 1 0 MarC family integral membrane protein Ribosomal_S3Ae PF01015.18 KPA44665.1 - 4.6e-88 294.1 1.4 5.6e-88 293.8 1.4 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Ribosomal_L22 PF00237.19 KPA44665.1 - 0.0023 18.1 0.1 0.0051 17.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SUI1 PF01253.22 KPA44665.1 - 0.019 15.5 0.2 0.061 13.8 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor SUI1 Erythro-docking PF09277.11 KPA44665.1 - 0.021 14.7 0.2 8.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Erythronolide synthase, docking NEMO PF11577.8 KPA44665.1 - 0.051 13.6 0.7 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO TipAS PF07739.13 KPA44665.1 - 0.13 12.8 0.1 2.6 8.6 0.0 2.4 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain AMP-binding PF00501.28 KPA44666.1 - 1.7e-76 257.5 0.4 2.8e-76 256.8 0.4 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Abhydrolase_1 PF00561.20 KPA44666.1 - 3e-25 89.3 0.0 5.5e-19 68.8 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA44666.1 - 4.8e-15 56.8 0.6 2.5e-14 54.4 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA44666.1 - 1e-10 41.3 0.0 3.4e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KPA44666.1 - 0.00013 22.2 0.0 0.00028 21.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.6 KPA44666.1 - 0.0002 22.3 0.0 0.00068 20.6 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PGAP1 PF07819.13 KPA44666.1 - 0.00042 20.1 1.0 0.023 14.4 0.1 2.7 2 1 0 2 2 2 1 PGAP1-like protein Esterase PF00756.20 KPA44666.1 - 0.0025 17.5 0.0 0.0075 15.9 0.0 1.8 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KPA44666.1 - 0.085 11.8 0.1 0.75 8.7 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme Zn_clus PF00172.18 KPA44667.1 - 0.00029 20.9 12.7 0.0028 17.7 12.7 2.2 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KPA44668.1 - 4.4e-10 39.3 0.0 1.3e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Sperm_act_pep PF08250.11 KPA44668.1 - 4.7 8.0 4.6 7.6 7.3 1.0 2.6 2 0 0 2 2 2 0 Sperm-activating peptides Diphthamide_syn PF01866.17 KPA44669.1 - 1.4e-87 294.0 0.0 1.6e-87 293.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MARVEL PF01284.23 KPA44670.1 - 2.6e-06 27.5 15.5 3.8e-06 27.0 15.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4293 PF14126.6 KPA44670.1 - 0.063 13.5 10.2 0.019 15.2 5.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) 7TMR-DISM_7TM PF07695.11 KPA44670.1 - 1.1 9.1 19.7 0.79 9.6 14.9 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling SCAMP PF04144.13 KPA44670.1 - 8.4 6.7 17.5 0.41 10.9 8.8 2.5 2 1 0 2 2 2 0 SCAMP family MARVEL PF01284.23 KPA44672.1 - 1.4e-15 57.6 19.5 1.7e-15 57.3 19.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1980 PF09323.10 KPA44672.1 - 0.38 10.7 3.7 0.16 11.9 1.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Rnf-Nqr PF02508.14 KPA44673.1 - 0.066 13.2 0.4 0.066 13.2 0.4 2.3 2 0 0 2 2 2 0 Rnf-Nqr subunit, membrane protein Phage_holin_3_6 PF07332.11 KPA44673.1 - 0.64 10.1 6.4 3.5 7.7 0.5 2.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III GDPD PF03009.17 KPA44674.1 - 1.6e-12 47.8 0.0 2.5e-12 47.1 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Toprim_4 PF13662.6 KPA44674.1 - 0.094 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Toprim domain Glyco_hydro_18 PF00704.28 KPA44675.1 - 5.3e-60 203.8 0.0 6.2e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL15 PF14885.6 KPA44675.1 - 0.042 13.8 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 HATPase_c PF02518.26 KPA44676.1 - 5e-22 78.5 0.0 1.1e-21 77.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPA44676.1 - 1.7e-18 66.8 0.0 6.4e-18 65.0 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KPA44676.1 - 2.6e-10 40.2 0.1 6.1e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ANAPC4_WD40 PF12894.7 KPA44677.1 - 0.0065 16.8 0.0 2.3 8.5 0.0 3.6 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPA44677.1 - 0.12 13.3 7.6 2 9.4 0.0 5.2 6 0 0 6 6 6 0 WD domain, G-beta repeat CDC45 PF02724.14 KPA44677.1 - 2.6 6.2 5.0 3.5 5.8 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Fe-ADH PF00465.19 KPA44678.1 - 5.7e-15 55.0 0.1 3.5e-14 52.4 0.1 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KPA44678.1 - 5.1e-06 26.4 0.3 8e-06 25.7 0.3 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Xan_ur_permease PF00860.20 KPA44679.1 - 8.2e-62 209.1 36.2 7.8e-61 205.9 36.2 2.0 1 1 0 1 1 1 1 Permease family NDUF_B12 PF08122.12 KPA44679.1 - 0.085 12.9 1.6 21 5.2 0.1 3.8 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family AA_permease_2 PF13520.6 KPA44681.1 - 1e-50 172.8 16.3 1.7e-42 145.7 8.1 3.2 1 1 2 3 3 3 3 Amino acid permease AA_permease PF00324.21 KPA44681.1 - 3.3e-12 45.8 5.3 3.3e-12 45.8 5.3 2.8 2 2 2 4 4 4 1 Amino acid permease OppC_N PF12911.7 KPA44681.1 - 0.15 12.0 3.5 4.2 7.4 0.0 3.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C mRNA_triPase PF02940.15 KPA44682.1 - 2.4e-53 181.1 0.0 3.6e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Flu_B_NS1 PF02942.14 KPA44682.1 - 0.22 10.6 0.2 0.38 9.8 0.2 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) RPN2_C PF18004.1 KPA44683.1 - 4.3e-58 195.8 5.5 8e-58 194.9 5.5 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KPA44683.1 - 4.5e-40 134.1 17.2 1.1e-08 35.0 0.0 8.1 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KPA44683.1 - 4.8e-22 78.1 0.1 3.8e-14 52.8 0.0 5.5 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 KPA44683.1 - 3e-06 27.0 0.8 3.9 8.0 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 KPA44683.1 - 1.2e-05 25.7 0.4 0.02 15.4 0.0 5.3 4 1 1 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 KPA44683.1 - 0.0054 16.8 0.9 3.1 7.8 0.0 3.6 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KPA44683.1 - 1.6 9.6 4.5 68 4.6 0.0 5.3 5 1 0 5 5 5 0 PBS lyase HEAT-like repeat Oxidored_molyb PF00174.19 KPA44684.1 - 2.3e-54 183.6 0.0 3.5e-54 183.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KPA44684.1 - 2.5e-31 108.5 0.2 4.3e-31 107.8 0.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KPA44684.1 - 3.7e-14 52.6 0.3 6.6e-14 51.8 0.3 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.16 KPA44687.1 - 9.9e-33 113.5 24.9 9.9e-33 113.5 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1769 PF08588.10 KPA44688.1 - 4.4e-28 97.3 0.5 1e-27 96.1 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) pPIWI_RE_REase PF18154.1 KPA44689.1 - 0.16 11.9 0.0 3.3 7.7 0.0 2.2 1 1 1 2 2 2 0 REase associating with pPIWI_RE Abhydrolase_1 PF00561.20 KPA44690.1 - 1.1e-05 25.2 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA44690.1 - 0.0078 16.8 1.7 0.0078 16.8 1.7 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KPA44690.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Ser_hydrolase PF06821.13 KPA44690.1 - 0.041 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase LIDHydrolase PF10230.9 KPA44690.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 KPA44690.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Cupin_2 PF07883.11 KPA44691.1 - 9.5e-12 44.5 0.0 1.3e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KPA44691.1 - 0.00038 20.1 0.0 0.00047 19.8 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KPA44691.1 - 0.0017 18.3 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KPA44691.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ARD PF03079.14 KPA44691.1 - 0.047 13.9 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 ARD/ARD' family MannoseP_isomer PF01050.18 KPA44691.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase CENP-C_C PF11699.8 KPA44691.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like DUF3506 PF12014.8 KPA44692.1 - 1.3e-48 164.5 0.0 2.4e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KPA44692.1 - 3.2e-08 33.3 1.1 3.2e-08 33.3 1.1 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KPA44692.1 - 6.4e-08 32.3 0.7 1.8e-07 30.9 0.7 1.7 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KPA44692.1 - 0.00019 21.9 0.0 0.00043 20.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A PRANC PF09372.10 KPA44692.1 - 0.079 13.3 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 PRANC domain DUF1581 PF07619.11 KPA44692.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) Polysacc_synt_4 PF04669.13 KPA44693.1 - 2.2e-22 79.5 2.0 1.5e-20 73.6 2.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis CUE PF02845.16 KPA44693.1 - 0.052 13.3 0.2 0.099 12.4 0.2 1.5 1 0 0 1 1 1 0 CUE domain AChE_tetra PF08674.10 KPA44693.1 - 0.12 12.0 2.3 0.26 11.0 2.3 1.5 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain ABC_membrane PF00664.23 KPA44694.1 - 5.1e-87 292.0 25.2 2.7e-48 165.0 1.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA44694.1 - 2e-62 209.7 0.0 1.3e-30 106.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPA44694.1 - 1.8e-15 57.0 3.3 9.7e-06 25.2 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPA44694.1 - 1.8e-12 47.7 0.0 0.0035 17.2 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPA44694.1 - 1.8e-07 30.8 1.5 0.01 15.5 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KPA44694.1 - 1.6e-06 28.6 0.8 0.095 13.1 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KPA44694.1 - 9.6e-06 25.6 0.3 0.084 12.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KPA44694.1 - 1.9e-05 25.0 3.3 0.43 10.9 0.2 4.0 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KPA44694.1 - 2.7e-05 23.2 0.2 0.0076 15.1 0.0 3.1 3 1 0 3 3 3 1 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 KPA44694.1 - 0.00014 21.9 0.1 0.5 10.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KPA44694.1 - 0.00038 21.0 0.5 0.36 11.3 0.7 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KPA44694.1 - 0.0059 16.4 0.0 7.7 6.1 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.17 KPA44694.1 - 0.0063 16.3 0.2 9.8 5.9 0.0 3.5 4 0 0 4 4 3 0 IstB-like ATP binding protein Dynamin_N PF00350.23 KPA44694.1 - 0.0065 16.6 0.3 2.7 8.0 0.0 2.4 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.6 KPA44694.1 - 0.0095 16.1 1.4 1.7 8.9 0.2 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KPA44694.1 - 0.013 15.1 0.0 5.4 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KPA44694.1 - 0.016 14.9 0.0 2.9 7.6 0.0 3.1 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.22 KPA44694.1 - 0.032 13.4 0.4 4.9 6.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF3987 PF13148.6 KPA44694.1 - 0.032 13.2 0.1 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_33 PF13671.6 KPA44694.1 - 0.037 14.2 0.0 14 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KPA44694.1 - 0.058 12.0 0.0 7 5.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KPA44694.1 - 0.082 12.2 0.0 15 4.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 KPA44694.1 - 0.17 12.3 0.5 18 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 KPA44694.1 - 0.18 11.8 0.4 26 4.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KPA44694.1 - 0.21 11.5 0.1 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AIG1 PF04548.16 KPA44694.1 - 0.23 10.7 1.3 2.5 7.4 0.0 2.8 3 0 0 3 3 3 0 AIG1 family FtsK_SpoIIIE PF01580.18 KPA44694.1 - 0.27 10.5 0.8 20 4.4 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.18 KPA44694.1 - 0.32 10.7 0.7 3.6 7.3 0.2 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 KPA44694.1 - 1.6 8.8 5.1 4.4 7.3 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ATPase PF06745.13 KPA44694.1 - 7.9 5.8 6.4 2.4 7.4 0.1 3.0 4 0 0 4 4 4 0 KaiC bZIP_1 PF00170.21 KPA44695.1 - 0.0064 16.6 5.5 0.013 15.6 5.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPA44695.1 - 0.46 10.6 11.0 0.87 9.7 11.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Cation_ATPase_C PF00689.21 KPA44696.1 - 2.5e-41 141.4 4.3 2.5e-41 141.4 4.3 3.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KPA44696.1 - 1.8e-37 128.6 3.5 1.8e-37 128.6 3.5 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KPA44696.1 - 1.7e-21 76.1 0.0 3.2e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPA44696.1 - 5.4e-16 59.5 0.0 4.1e-15 56.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPA44696.1 - 2e-07 30.6 0.2 6.7e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPA44696.1 - 2.4e-05 24.2 0.3 0.00024 20.9 0.5 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NUP PF06516.11 KPA44697.1 - 1.2e-128 428.7 0.0 1.4e-128 428.5 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Pkinase PF00069.25 KPA44698.1 - 2.2e-43 148.5 0.0 1.9e-42 145.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA44698.1 - 2.7e-29 102.2 0.0 3.9e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPA44698.1 - 0.00092 18.6 0.0 0.0087 15.4 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KPA44698.1 - 0.0035 16.7 0.0 0.0075 15.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Zn_clus PF00172.18 KPA44699.1 - 4.8e-06 26.6 5.4 1.2e-05 25.3 5.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAN_1 PF00024.26 KPA44700.1 - 3e-09 36.7 36.8 0.0033 17.3 7.3 5.1 3 1 2 5 5 5 4 PAN domain PAN_4 PF14295.6 KPA44700.1 - 0.052 13.5 0.7 0.052 13.5 0.7 5.6 4 1 0 4 4 4 0 PAN domain CTD PF12815.7 KPA44701.1 - 1.3e-23 83.4 28.2 1.6e-18 67.0 16.2 4.3 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.13 KPA44701.1 - 1.9e-23 82.1 0.1 3.3e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KPA44701.1 - 7.1e-21 75.0 6.1 7.1e-21 75.0 6.1 3.6 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KPA44701.1 - 0.00066 19.5 1.9 0.00066 19.5 1.9 4.9 6 0 0 6 6 6 2 KOW motif Cornifin PF02389.15 KPA44701.1 - 0.031 14.5 6.4 0.07 13.3 6.4 1.5 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF3912 PF13051.6 KPA44701.1 - 0.12 12.6 1.0 0.32 11.3 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) LSM_int_assoc PF16605.5 KPA44701.1 - 0.3 11.2 2.5 0.3 11.2 0.2 2.3 2 0 0 2 2 2 0 LSM-interacting associated unstructured DDRGK PF09756.9 KPA44701.1 - 3.2 7.3 20.3 7.2 6.1 20.3 1.6 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.12 KPA44701.1 - 5.7 6.7 13.6 11 5.7 13.6 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WD40 PF00400.32 KPA44702.1 - 3.1e-13 50.0 4.9 2.1e-05 25.2 0.0 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Serglycin PF04360.12 KPA44702.1 - 0.043 13.8 1.8 0.11 12.5 1.8 1.6 1 0 0 1 1 1 0 Serglycin DUF4831 PF16115.5 KPA44702.1 - 0.27 10.3 0.0 0.42 9.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4831) Filament PF00038.21 KPA44703.1 - 0.0092 15.6 4.7 0.0092 15.6 4.7 2.3 2 0 0 2 2 2 1 Intermediate filament protein DUF4600 PF15372.6 KPA44703.1 - 0.012 16.1 4.0 0.074 13.5 4.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Erp_C PF06780.11 KPA44703.1 - 0.063 13.3 2.6 0.35 10.9 1.2 2.2 2 0 0 2 2 2 0 Erp protein C-terminus Spc7 PF08317.11 KPA44703.1 - 0.069 12.0 13.5 0.045 12.6 4.6 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.6 KPA44703.1 - 1 9.1 9.7 0.58 9.9 4.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) MCU PF04678.13 KPA44703.1 - 1.1 9.3 6.4 1.3 9.1 1.2 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Leu_zip PF15294.6 KPA44703.1 - 1.2 8.6 10.9 4.1 6.9 0.8 2.5 2 0 0 2 2 2 0 Leucine zipper Ribosomal_60s PF00428.19 KPA44703.1 - 6 7.5 8.6 2.9 8.5 3.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nup88 PF10168.9 KPA44703.1 - 6.3 4.5 10.1 0.32 8.8 1.9 2.1 2 0 0 2 2 2 0 Nuclear pore component GrpE PF01025.19 KPA44703.1 - 8.6 6.0 8.1 9.2 5.9 2.5 2.6 2 0 0 2 2 2 0 GrpE DUF1748 PF08520.10 KPA44704.1 - 7.8e-33 112.2 0.1 9.4e-33 111.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.21 KPA44705.1 - 1.8e-170 566.5 3.8 2.2e-170 566.1 3.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KPA44705.1 - 1.9e-37 128.0 0.0 1.6e-36 125.1 0.0 2.4 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KPA44705.1 - 8e-05 21.9 0.5 0.00079 18.6 0.2 2.2 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KPA44705.1 - 0.066 12.2 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain MFS_1 PF07690.16 KPA44706.1 - 1.2e-46 159.3 31.3 1.2e-46 159.3 31.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA44706.1 - 3.9e-08 32.6 8.4 3.9e-08 32.6 8.4 2.4 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KPA44706.1 - 2.6e-05 23.7 3.4 2.6e-05 23.7 3.4 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 KPA44706.1 - 0.002 16.4 0.9 0.025 12.8 0.3 2.3 1 1 1 2 2 2 1 BT1 family MFS_3 PF05977.13 KPA44706.1 - 0.0033 15.9 0.5 0.0053 15.2 0.5 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2583 PF10762.9 KPA44706.1 - 1.3 9.5 4.1 0.81 10.1 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) DUF4191 PF13829.6 KPA44706.1 - 3 7.1 7.1 1.1 8.5 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) GMC_oxred_N PF00732.19 KPA44707.1 - 5.2e-76 255.8 0.0 7.4e-76 255.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA44707.1 - 1e-33 116.8 0.0 2.2e-33 115.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KPA44707.1 - 0.00011 21.4 0.1 0.00016 20.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPA44707.1 - 0.00028 20.1 0.1 0.47 9.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KPA44707.1 - 0.0041 16.4 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA44707.1 - 0.0085 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KPA44707.1 - 0.018 14.7 1.6 0.25 10.9 1.5 2.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA44707.1 - 0.12 12.9 0.1 0.59 10.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TEX13 PF15186.6 KPA44708.1 - 4 7.1 5.1 14 5.4 3.8 2.2 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family PIG-H PF10181.9 KPA44709.1 - 1.3e-25 89.0 0.1 2e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.20 KPA44710.1 - 4.4e-36 123.6 0.0 4e-35 120.5 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase Ras PF00071.22 KPA44711.1 - 2.6e-19 69.4 0.0 3.5e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KPA44711.1 - 1.7e-07 30.8 0.0 4e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KPA44711.1 - 5.3e-07 29.9 0.0 1.3e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KPA44711.1 - 0.027 13.7 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 KPA44711.1 - 0.041 13.6 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KPA44711.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KPA44711.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KPA44711.1 - 0.19 12.3 0.0 0.37 11.4 0.0 1.7 1 1 1 2 2 2 0 AAA domain RNA_pol_Rpb4 PF03874.16 KPA44712.1 - 9.3e-26 90.6 0.0 1.1e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Glyco_transf_54 PF04666.13 KPA44712.1 - 0.024 13.5 0.0 0.025 13.4 0.0 1.2 1 1 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Polysacc_deac_2 PF04748.13 KPA44712.1 - 0.043 13.0 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Pribosyl_synth PF14572.6 KPA44713.1 - 8.9e-43 146.5 0.9 1.2e-37 129.8 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KPA44713.1 - 4.9e-32 110.3 0.0 1e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KPA44713.1 - 1.1e-17 64.0 0.1 2e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KPA44713.1 - 0.0016 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KPA44713.1 - 0.025 14.1 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase dCMP_cyt_deam_1 PF00383.23 KPA44714.1 - 1.4e-09 37.7 0.0 1.8e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KPA44714.1 - 8.2e-08 32.1 0.0 9.4e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase DUF5536 PF17688.1 KPA44714.1 - 0.08 12.8 0.2 0.15 11.9 0.2 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5536) Snf7 PF03357.21 KPA44716.1 - 3.9e-21 75.4 10.3 3.9e-21 75.4 10.3 1.9 1 1 1 2 2 2 1 Snf7 WAPL PF07814.13 KPA44716.1 - 0.057 12.2 2.3 0.073 11.8 0.7 1.7 1 1 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin V_ATPase_I PF01496.19 KPA44716.1 - 2.3 6.0 7.8 0.14 10.0 3.0 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GAS PF13851.6 KPA44716.1 - 2.6 7.4 14.9 0.032 13.6 7.3 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KPA44716.1 - 8.5 6.5 17.0 0.17 12.0 7.0 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CS PF04969.16 KPA44717.1 - 4.6e-09 37.2 0.5 7.2e-09 36.5 0.5 1.3 1 0 0 1 1 1 1 CS domain RRM_1 PF00076.22 KPA44718.1 - 1.4e-17 63.3 0.0 2.6e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KPA44718.1 - 5.7e-05 23.6 1.3 5.7e-05 23.6 1.3 2.8 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KPA44718.1 - 0.0048 16.7 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Peptidase_M35 PF02102.15 KPA44718.1 - 0.024 13.5 3.8 0.041 12.8 3.8 1.3 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family DFRP_C PF16543.5 KPA44719.1 - 3.8e-26 91.4 8.1 3.8e-26 91.4 8.1 3.4 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 KPA44719.1 - 3.1e-06 26.8 9.5 0.00087 19.0 2.2 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 KPA44719.1 - 1.1e-05 25.2 1.1 1.1e-05 25.2 1.1 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KPA44719.1 - 2.2e-05 25.1 4.4 2.2e-05 25.1 4.4 3.7 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 KPA44719.1 - 0.00014 21.8 6.9 0.00014 21.8 6.9 3.2 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 KPA44719.1 - 0.0033 17.6 0.7 0.13 12.4 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KPA44719.1 - 0.56 10.8 15.0 0.51 10.9 5.6 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Mito_carr PF00153.27 KPA44720.1 - 3.1e-37 126.4 8.7 2.2e-13 50.0 0.4 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1269 PF06897.12 KPA44720.1 - 0.046 14.0 0.2 0.26 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) AT_hook PF02178.19 KPA44721.1 - 0.082 12.8 14.8 1.4 9.0 2.4 3.2 2 0 0 2 2 2 0 AT hook motif Meth_synt_2 PF01717.18 KPA44722.1 - 6.8e-153 508.7 0.0 4.6e-147 489.5 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KPA44722.1 - 1.6e-121 405.7 0.0 2.4e-114 382.1 0.0 3.1 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KPA44722.1 - 0.0026 17.0 0.0 0.076 12.1 0.0 2.4 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) Noggin PF05806.12 KPA44723.1 - 0.95 9.3 4.9 0.24 11.3 0.4 2.3 3 0 0 3 3 3 0 Noggin MFS_1 PF07690.16 KPA44724.1 - 3.3e-44 151.3 30.6 3.3e-44 151.3 30.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA44724.1 - 2.3e-13 49.8 2.2 2.3e-13 49.8 2.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPA44724.1 - 1.4e-07 30.3 1.1 1.4e-07 30.3 1.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 KPA44724.1 - 7.2e-05 21.8 4.2 0.00014 20.9 4.2 1.5 1 0 0 1 1 1 1 POT family MFS_4 PF06779.14 KPA44724.1 - 0.59 9.4 14.3 0.14 11.4 5.5 2.8 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Prefoldin_2 PF01920.20 KPA44725.1 - 2.2e-26 91.9 11.4 3.1e-26 91.4 11.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KPA44725.1 - 0.019 14.9 3.6 0.019 14.9 3.6 2.2 1 1 1 2 2 2 0 Prefoldin subunit SPATA24 PF15175.6 KPA44725.1 - 0.045 13.6 10.9 0.059 13.3 10.9 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 PP_kinase_N PF13089.6 KPA44725.1 - 0.047 14.0 0.7 0.047 14.0 0.7 1.9 1 1 0 2 2 2 0 Polyphosphate kinase N-terminal domain Carbpep_Y_N PF05388.11 KPA44725.1 - 0.07 13.7 0.8 0.092 13.3 0.8 1.2 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Syntaxin-6_N PF09177.11 KPA44725.1 - 0.33 11.5 9.0 1.7 9.3 0.6 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spore_III_AB PF09548.10 KPA44725.1 - 0.55 10.3 7.8 0.86 9.7 7.8 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) AAA_23 PF13476.6 KPA44725.1 - 1 9.8 11.0 1.3 9.5 11.0 1.2 1 0 0 1 1 1 0 AAA domain PhoU PF01895.19 KPA44725.1 - 1.5 9.4 12.0 6.6 7.3 0.9 2.2 1 1 0 2 2 2 0 PhoU domain FAM167 PF11652.8 KPA44725.1 - 1.6 9.2 12.5 13 6.4 0.1 3.7 1 1 3 4 4 4 0 FAM167 KfrA_N PF11740.8 KPA44725.1 - 4.4 8.0 10.8 0.64 10.7 3.6 2.3 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term XhlA PF10779.9 KPA44725.1 - 7 6.9 8.5 0.3 11.3 1.5 2.2 2 0 0 2 2 2 0 Haemolysin XhlA CBFD_NFYB_HMF PF00808.23 KPA44726.1 - 9.9e-05 22.6 0.2 0.00014 22.1 0.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 KPA44726.1 - 0.0072 16.5 0.0 0.0077 16.4 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein CENP-X PF09415.10 KPA44726.1 - 0.12 12.7 0.6 0.18 12.1 0.6 1.4 1 1 0 1 1 1 0 CENP-S associating Centromere protein X Homeobox_KN PF05920.11 KPA44726.1 - 0.17 11.8 0.2 0.27 11.2 0.2 1.6 1 1 0 1 1 1 0 Homeobox KN domain GrpE PF01025.19 KPA44727.1 - 0.55 9.9 15.6 0.11 12.2 11.0 2.1 1 1 1 2 2 2 0 GrpE GRP PF07172.11 KPA44727.1 - 0.58 10.9 12.1 1.9 9.2 12.1 1.9 1 0 0 1 1 1 0 Glycine rich protein family HSP70 PF00012.20 KPA44728.1 - 9.4e-52 176.0 11.0 9.4e-52 176.0 11.0 3.7 1 1 1 3 3 3 1 Hsp70 protein PAPS_reduct PF01507.19 KPA44728.1 - 0.062 13.3 0.2 0.17 11.9 0.2 1.8 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Peptidase_M22 PF00814.25 KPA44728.1 - 0.075 12.7 1.2 0.18 11.4 1.2 1.6 1 0 0 1 1 1 0 Glycoprotease family Asp PF00026.23 KPA44729.1 - 8.2e-43 147.0 0.0 3e-35 122.2 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA44729.1 - 4.3e-07 30.3 0.0 0.013 15.8 0.0 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KPA44729.1 - 3.7e-05 23.6 0.0 0.00012 21.9 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KPA44729.1 - 0.0026 18.3 0.3 0.31 11.7 0.0 2.5 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KPA44729.1 - 0.026 15.1 0.0 4.4 7.9 0.0 2.7 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease SKA1 PF07160.12 KPA44730.1 - 0.0016 18.3 1.8 0.0019 18.1 1.8 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 CENP-Q PF13094.6 KPA44730.1 - 0.0022 18.3 6.3 0.003 17.8 6.3 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.12 KPA44730.1 - 0.0035 17.9 3.1 0.0035 17.9 3.1 2.1 1 1 1 2 2 2 1 SlyX Tropomyosin PF00261.20 KPA44730.1 - 0.0065 15.9 3.7 0.0083 15.5 3.7 1.1 1 0 0 1 1 1 1 Tropomyosin Allexi_40kDa PF05549.11 KPA44730.1 - 0.0095 15.5 1.9 0.011 15.2 1.9 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein AAA_13 PF13166.6 KPA44730.1 - 0.017 13.8 1.0 0.02 13.6 1.0 1.1 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 KPA44730.1 - 0.028 13.5 0.9 0.028 13.5 0.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-K PF11802.8 KPA44730.1 - 0.04 13.5 1.9 0.053 13.1 1.9 1.1 1 0 0 1 1 1 0 Centromere-associated protein K UPF0242 PF06785.11 KPA44730.1 - 0.074 13.2 4.9 0.095 12.8 4.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Herpes_UL6 PF01763.16 KPA44730.1 - 0.13 10.8 0.8 0.14 10.7 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like YabA PF06156.13 KPA44730.1 - 0.17 12.6 1.4 0.24 12.1 1.4 1.2 1 0 0 1 1 1 0 Initiation control protein YabA V_ATPase_I PF01496.19 KPA44730.1 - 0.33 8.8 1.0 0.36 8.7 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 KPA44730.1 - 0.47 9.7 6.2 0.53 9.6 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 KPA44730.1 - 0.54 10.8 4.2 1.2 9.7 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 XhlA PF10779.9 KPA44730.1 - 0.6 10.4 2.3 0.99 9.7 2.3 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Ndc1_Nup PF09531.10 KPA44730.1 - 1.1 7.8 5.4 1.3 7.6 5.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spc24 PF08286.11 KPA44730.1 - 1.3 9.3 5.0 2.4 8.5 5.0 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 FAM76 PF16046.5 KPA44730.1 - 3.9 6.8 6.3 3.4 7.0 4.7 1.6 1 1 1 2 2 2 0 FAM76 protein Presenilin PF01080.17 KPA44730.1 - 9.8 4.8 5.5 11 4.6 5.5 1.0 1 0 0 1 1 1 0 Presenilin LapA_dom PF06305.11 KPA44731.1 - 0.18 11.6 2.2 0.33 10.8 2.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MIP PF00230.20 KPA44732.1 - 1.4e-47 162.3 15.8 1.8e-47 161.9 15.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein COX4 PF02936.14 KPA44732.1 - 0.088 12.8 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DBC1 PF14443.6 KPA44732.1 - 0.092 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 DBC1 ANAPC10 PF03256.16 KPA44733.1 - 5.6e-49 166.3 0.0 8.7e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) CENP-B_dimeris PF09026.10 KPA44733.1 - 0.059 13.8 9.4 0.16 12.3 9.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 KPA44733.1 - 1.2 7.2 6.5 1.5 6.9 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 KPA44733.1 - 2.5 8.0 7.7 4.4 7.1 7.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Myb_DNA-binding PF00249.31 KPA44734.1 - 4.6e-19 68.3 4.3 9.7e-08 32.1 0.4 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPA44734.1 - 2.5e-15 56.5 6.1 1.9e-09 37.6 0.6 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KPA44734.1 - 0.027 14.9 2.3 0.17 12.3 0.4 3.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RseA_N PF03872.13 KPA44734.1 - 0.045 14.2 2.9 1.2 9.7 0.1 3.6 2 0 0 2 2 2 0 Anti sigma-E protein RseA, N-terminal domain SANT_DAMP1_like PF16282.5 KPA44734.1 - 0.075 13.2 0.5 0.22 11.7 0.2 2.0 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 KPA44734.1 - 0.26 11.6 5.6 9.9 6.6 0.4 3.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AAA_16 PF13191.6 KPA44735.1 - 3e-06 27.7 0.0 8.1e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KPA44735.1 - 1.3e-05 25.2 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 KPA44735.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 KPA44735.1 - 0.02 14.5 0.0 0.064 12.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KPA44735.1 - 0.028 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 KPA44735.1 - 0.043 13.0 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Fungal_trans_2 PF11951.8 KPA44738.1 - 2.3e-34 118.8 2.4 9.9e-22 77.3 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA44738.1 - 1.2e-08 34.9 12.2 2.3e-08 34.0 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KPA44738.1 - 0.073 13.0 5.1 0.26 11.3 5.1 2.0 1 0 0 1 1 1 0 AT hook motif Pex14_N PF04695.13 KPA44740.1 - 0.013 16.1 3.1 0.017 15.7 3.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1180 PF06679.12 KPA44740.1 - 0.014 15.8 6.3 0.095 13.1 6.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Tim54 PF11711.8 KPA44740.1 - 0.091 11.5 3.4 0.1 11.4 3.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 KPA44740.1 - 0.098 11.9 0.3 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIIAH PF12685.7 KPA44740.1 - 0.18 11.6 11.3 0.22 11.3 11.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Mucin PF01456.17 KPA44740.1 - 0.2 11.6 16.1 0.27 11.2 16.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Presenilin PF01080.17 KPA44740.1 - 0.28 9.9 6.6 0.33 9.7 6.6 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 KPA44740.1 - 0.35 9.6 6.3 0.39 9.4 6.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GREB1 PF15782.5 KPA44740.1 - 0.88 6.6 2.7 0.95 6.5 2.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAPS PF04499.15 KPA44740.1 - 1.4 7.6 8.9 1.6 7.4 8.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.16 KPA44740.1 - 1.9 7.6 5.6 2.4 7.3 5.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TP53IP5 PF15331.6 KPA44740.1 - 2.5 8.2 5.5 3 8.0 5.5 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SLC12 PF03522.15 KPA44740.1 - 3.4 6.6 5.9 4 6.3 5.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 KPA44740.1 - 5.2 6.0 6.4 6.2 5.7 6.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 KPA44740.1 - 5.7 6.7 11.4 7.2 6.4 11.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4820 PF16091.5 KPA44740.1 - 5.8 6.2 6.7 9.2 5.6 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Menin PF05053.13 KPA44740.1 - 6.1 5.1 7.4 7.4 4.8 7.4 1.1 1 0 0 1 1 1 0 Menin CDC45 PF02724.14 KPA44740.1 - 7.4 4.7 11.6 8.9 4.5 11.6 1.0 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 KPA44741.1 - 1e-32 113.4 22.2 1e-31 110.2 24.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 KPA44741.1 - 0.063 13.0 0.4 0.063 13.0 0.4 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like FixQ PF05545.11 KPA44741.1 - 0.42 10.6 0.1 0.42 10.6 0.1 3.6 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ DAG1 PF05454.11 KPA44742.1 - 0.044 13.2 0.9 0.099 12.0 0.0 2.0 2 1 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) NAD_binding_6 PF08030.12 KPA44743.1 - 2.6e-32 112.1 0.0 4.3e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPA44743.1 - 5.7e-21 74.6 0.2 3.3e-20 72.2 0.0 2.3 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 KPA44743.1 - 1.5e-16 60.6 12.8 1.5e-16 60.6 12.8 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KPA44743.1 - 0.06 14.0 0.0 0.21 12.3 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain UQ_con PF00179.26 KPA44744.1 - 8.9e-53 177.7 0.0 1e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPA44744.1 - 0.0037 17.0 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KPA44744.1 - 0.034 14.4 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KPA44744.1 - 0.044 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_1 PF00441.24 KPA44745.1 - 6.5e-25 88.1 0.4 1e-24 87.4 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPA44745.1 - 4.4e-24 85.3 0.2 8.5e-24 84.4 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KPA44745.1 - 6e-17 61.6 0.0 1.1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPA44745.1 - 9.6e-06 25.9 0.3 1.9e-05 24.9 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LrgB PF04172.16 KPA44746.1 - 1.2e-56 191.6 8.3 1.2e-56 191.6 8.3 2.1 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 KPA44746.1 - 0.00016 21.6 10.3 0.00016 21.6 10.3 3.0 3 1 1 4 4 4 1 LrgA family ADP_ribosyl_GH PF03747.14 KPA44746.1 - 0.014 15.1 0.5 0.023 14.4 0.5 1.3 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF4112 PF13430.6 KPA44746.1 - 0.032 14.5 1.1 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) DUF4834 PF16118.5 KPA44746.1 - 0.14 13.1 0.3 0.33 11.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pol_alpha_B_N PF08418.10 KPA44746.1 - 0.2 11.6 0.1 0.31 11.0 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Linker_histone PF00538.19 KPA44748.1 - 8.3e-28 96.6 0.1 8.3e-28 96.6 0.1 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family Mitofilin PF09731.9 KPA44748.1 - 2.2 7.0 36.0 2.4 6.9 36.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HC2 PF07382.11 KPA44748.1 - 4.5 7.3 91.3 0.15 12.2 85.1 1.6 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 Sec23_trunk PF04811.15 KPA44749.1 - 1.8e-52 178.3 0.0 3.5e-52 177.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KPA44749.1 - 2e-22 79.0 0.0 3.9e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KPA44749.1 - 7.5e-18 65.1 0.0 1.4e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KPA44749.1 - 6.8e-15 54.8 4.7 1.3e-14 53.9 4.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KPA44749.1 - 9.5e-06 25.4 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF2263 PF10021.9 KPA44750.1 - 6.2e-08 33.1 0.0 9.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) VlpA_repeat PF04649.12 KPA44750.1 - 1.1 9.7 3.0 0.56 10.5 0.2 2.0 2 0 0 2 2 2 0 Mycoplasma hyorhinis VlpA repeat tRNA-synt_2 PF00152.20 KPA44751.1 - 6.7e-83 278.4 0.0 1.5e-82 277.2 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KPA44751.1 - 4.8e-10 39.3 0.0 9.2e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KPA44751.1 - 0.16 11.5 0.0 7.7 5.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Gti1_Pac2 PF09729.9 KPA44752.1 - 3.3e-44 151.1 3.4 1.6e-37 129.3 0.2 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family Lactamase_B_6 PF16661.5 KPA44753.1 - 1.5e-64 217.0 0.0 2.3e-64 216.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KPA44753.1 - 6e-55 186.0 0.0 6e-55 186.0 0.0 2.3 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 KPA44753.1 - 4.9e-17 61.6 0.0 1.2e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 KPA44753.1 - 1.3e-15 57.7 0.0 4.2e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain SYS1 PF09801.9 KPA44754.1 - 2.3e-47 160.8 2.9 2.6e-47 160.6 2.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COX6B PF02297.17 KPA44755.1 - 5.8e-21 74.5 3.4 7.3e-21 74.2 3.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb EKLF_TAD2 PF16833.5 KPA44755.1 - 0.016 15.2 0.2 0.031 14.3 0.2 1.4 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 2 PIP5K PF01504.18 KPA44756.1 - 4.3e-101 337.7 0.0 4.3e-101 337.7 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Erythro-docking PF09277.11 KPA44756.1 - 0.049 13.5 0.9 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 Erythronolide synthase, docking DEAD PF00270.29 KPA44757.1 - 2.1e-42 144.9 0.0 3.1e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA44757.1 - 9.3e-28 96.8 0.6 5.6e-27 94.3 0.4 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA44757.1 - 0.00096 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KPA44757.1 - 0.11 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit API5 PF05918.11 KPA44757.1 - 0.48 9.2 6.7 0.84 8.4 6.7 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Acyl-CoA_dh_1 PF00441.24 KPA44758.1 - 2.8e-40 138.0 0.2 3.8e-40 137.5 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPA44758.1 - 2e-21 76.0 0.1 4.2e-21 75.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPA44758.1 - 4.1e-21 75.7 0.0 8.9e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 KPA44758.1 - 6.9e-21 74.2 0.2 1.3e-20 73.3 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 KPA44758.1 - 2.8e-07 30.9 0.0 5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 KPA44758.1 - 0.1 13.1 0.0 0.68 10.5 0.0 2.2 1 1 1 2 2 2 0 C6 domain XPG_N PF00752.17 KPA44759.1 - 8.8e-32 109.6 0.0 8.8e-32 109.6 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KPA44759.1 - 2.6e-31 107.8 1.1 5.4e-31 106.8 0.0 2.1 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KPA44759.1 - 3.1e-05 24.5 0.8 0.00014 22.3 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KPA44759.1 - 0.087 13.4 0.0 0.29 11.8 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain WSC PF01822.19 KPA44761.1 - 5.9e-10 39.2 10.7 5.9e-10 39.2 10.7 1.8 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 KPA44761.1 - 7.8e-08 31.6 7.5 1.8e-07 30.4 7.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KPA44761.1 - 3.5e-05 24.0 0.1 5.6e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.6 KPA44761.1 - 0.00066 19.7 0.4 0.0011 19.0 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Alpha_GJ PF03229.13 KPA44761.1 - 0.012 16.2 7.0 0.022 15.3 7.0 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J Insulin_TMD PF17870.1 KPA44761.1 - 0.055 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RskA PF10099.9 KPA44761.1 - 0.77 10.0 9.1 0.22 11.8 6.0 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA NACHT PF05729.12 KPA44765.1 - 1.6e-11 44.4 0.0 3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPA44765.1 - 1.6e-05 25.4 0.0 4.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KPA44765.1 - 0.00069 18.9 0.0 0.025 13.9 0.0 2.6 3 0 0 3 3 3 1 KAP family P-loop domain RNA_helicase PF00910.22 KPA44765.1 - 0.0036 17.7 0.0 0.0081 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.20 KPA44765.1 - 0.036 13.9 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_25 PF13481.6 KPA44765.1 - 0.063 12.8 0.0 0.2 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KPA44765.1 - 0.07 13.4 0.0 0.22 11.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain Asp PF00026.23 KPA44766.1 - 4.1e-111 371.4 0.0 4.9e-111 371.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA44766.1 - 1e-14 55.1 0.7 2e-12 47.7 0.7 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPA44766.1 - 0.00011 22.7 0.0 1.1 9.9 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KPA44766.1 - 0.00011 22.0 0.0 0.0018 18.1 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KPA44766.1 - 0.00023 21.7 0.0 1.4 9.5 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease DUF155 PF02582.14 KPA44768.1 - 3.2e-46 157.6 0.0 4.5e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_1 PF00190.22 KPA44768.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Cupin CRAL_TRIO PF00650.20 KPA44769.1 - 1.8e-36 125.2 0.0 2.6e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KPA44769.1 - 1.6e-07 31.4 0.1 4.3e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KPA44769.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KPA44769.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Mis14 PF08641.12 KPA44770.1 - 3.6e-20 72.6 1.0 3.6e-20 72.6 1.0 1.9 2 1 0 2 2 2 1 Kinetochore protein Mis14 like EFG_IV PF03764.18 KPA44770.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G, domain IV His_Phos_2 PF00328.22 KPA44771.1 - 3.3e-31 109.0 0.0 4.2e-30 105.4 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Fungal_trans_2 PF11951.8 KPA44771.1 - 6.2e-07 28.6 1.0 8.8e-07 28.1 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA44771.1 - 6.2e-06 26.2 2.1 1.7e-05 24.9 2.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Attacin_N PF03768.15 KPA44772.1 - 0.00071 19.7 0.5 1 9.6 0.1 2.7 2 0 0 2 2 2 2 Attacin, N-terminal region DUF4960 PF16324.5 KPA44772.1 - 0.048 13.2 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4960) UPF0180 PF03698.13 KPA44772.1 - 0.1 12.8 0.0 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) Beta-lactamase PF00144.24 KPA44773.1 - 5.9e-50 170.4 0.0 7.6e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KPA44773.1 - 0.0018 18.7 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DUF2924 PF11149.8 KPA44773.1 - 0.12 12.8 0.1 0.79 10.1 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) AMP-binding PF00501.28 KPA44774.1 - 1.4e-83 280.9 0.0 1.7e-83 280.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme F-box PF00646.33 KPA44775.1 - 5e-05 23.1 1.1 0.0002 21.2 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KPA44775.1 - 0.00067 19.5 0.1 0.0027 17.6 0.0 2.1 2 0 0 2 2 2 1 F-box-like Zn_clus PF00172.18 KPA44776.1 - 1.4e-09 37.9 10.7 2.6e-09 37.1 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA44776.1 - 0.0034 16.2 0.2 0.011 14.5 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ldl_recept_a PF00057.18 KPA44776.1 - 0.31 11.3 5.7 0.69 10.2 5.7 1.6 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A MFS_1 PF07690.16 KPA44777.1 - 3.8e-35 121.5 55.4 1.3e-34 119.7 54.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA44777.1 - 2.7e-14 52.5 26.8 6.3e-14 51.3 26.8 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPA44777.1 - 9.6e-13 47.8 4.5 9.6e-13 47.8 4.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter CHCH PF06747.13 KPA44778.1 - 0.00097 19.2 0.3 78 3.6 0.0 5.4 5 0 0 5 5 5 3 CHCH domain Abhydrolase_2 PF02230.16 KPA44779.1 - 2.3e-25 89.7 0.0 5.9e-20 72.0 0.0 2.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KPA44779.1 - 0.0016 17.8 0.0 0.024 13.9 0.0 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Cutinase PF01083.22 KPA44779.1 - 0.0033 17.4 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.21 KPA44779.1 - 0.023 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF5548 PF17702.1 KPA44780.1 - 0.062 13.0 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5548) GFA PF04828.14 KPA44781.1 - 1.2e-14 54.4 0.4 2e-14 53.7 0.4 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Eclosion PF04736.12 KPA44781.1 - 0.046 13.4 2.2 0.072 12.8 0.3 2.3 2 0 0 2 2 2 0 Eclosion hormone Oxidored_FMN PF00724.20 KPA44782.1 - 1.3e-60 205.5 0.0 1.5e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 KPA44782.1 - 0.058 13.1 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) MFS_1 PF07690.16 KPA44783.1 - 1.3e-15 57.2 23.0 1.3e-15 57.2 23.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2070 PF09843.9 KPA44783.1 - 3.4 5.9 5.6 6.1 5.0 5.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) LicD PF04991.13 KPA44784.1 - 7.1e-17 62.3 7.7 1.5e-11 44.8 5.1 2.3 1 1 1 2 2 2 2 LicD family HATPase_c_3 PF13589.6 KPA44785.1 - 1.6e-18 66.8 0.0 2.9e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KPA44785.1 - 4.9e-10 39.4 0.1 6e-09 35.8 0.1 2.4 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KPA44785.1 - 0.0002 21.8 0.0 0.00037 21.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Clathrin PF00637.20 KPA44787.1 - 9e-23 80.7 6.8 5.2e-22 78.3 1.9 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.8 KPA44787.1 - 2.9e-18 65.8 0.5 6.8e-18 64.6 0.5 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KPA44787.1 - 2.9e-06 27.2 5.8 6.6e-06 26.1 5.8 1.7 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KPA44787.1 - 3.4e-05 23.6 5.0 8.1e-05 22.4 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPA44787.1 - 0.00013 21.8 4.4 0.00027 20.8 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KPA44787.1 - 0.0052 16.6 4.4 0.0052 16.6 4.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA44787.1 - 0.033 14.5 5.5 0.092 13.1 5.5 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KPA44787.1 - 0.094 12.8 4.8 0.097 12.7 3.2 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 KPA44787.1 - 0.099 12.9 5.4 0.24 11.7 5.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Curto_V2 PF07325.11 KPA44787.1 - 0.25 11.2 0.8 0.62 9.9 0.8 1.6 1 0 0 1 1 1 0 Curtovirus V2 protein TPR_14 PF13428.6 KPA44787.1 - 0.26 12.2 1.5 36 5.5 0.1 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 KPA44787.1 - 0.35 10.9 1.5 0.89 9.7 1.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KPA44787.1 - 2.3 8.0 4.5 5.9 6.7 4.5 1.8 1 0 0 1 1 1 0 RING-like zinc finger SNF2_N PF00176.23 KPA44788.1 - 2.7e-27 95.4 0.0 4.3e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA44788.1 - 2.4e-06 27.8 0.0 6.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA44788.1 - 5.7e-05 23.2 0.0 0.00017 21.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KPA44788.1 - 0.1 12.9 0.2 2.8 8.2 0.0 2.9 2 2 0 2 2 2 0 AAA domain Methyltransf_23 PF13489.6 KPA44789.1 - 1.4e-13 51.0 0.0 2.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA44789.1 - 1.4e-09 38.5 0.0 2.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA44789.1 - 9.7e-08 32.6 0.0 3.3e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA44789.1 - 0.00017 21.4 0.0 0.013 15.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA44789.1 - 0.00082 20.1 0.0 0.0043 17.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA44789.1 - 0.0074 15.6 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pec_lyase_C PF00544.19 KPA44791.1 - 2.3e-16 60.0 11.5 6.8e-15 55.2 11.5 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KPA44791.1 - 1.1e-08 35.0 20.3 1.4e-07 31.5 11.5 2.3 1 1 1 2 2 2 2 Right handed beta helix region Phage_attach PF05354.11 KPA44791.1 - 0.05 13.5 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Phage Head-Tail Attachment F-box-like PF12937.7 KPA44792.1 - 0.019 14.8 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 F-box-like Na_Ca_ex PF01699.24 KPA44793.1 - 3.7e-22 78.9 28.2 6.4e-15 55.4 12.1 3.7 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KPA44793.1 - 1.2e-16 61.1 10.2 1.2e-16 61.1 10.2 4.6 5 0 0 5 5 5 1 Inner membrane component domain SURF2 PF05477.11 KPA44793.1 - 0.14 11.8 3.7 0.33 10.6 3.7 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) ATP1G1_PLM_MAT8 PF02038.16 KPA44793.1 - 2.3 7.7 4.6 1.4 8.4 0.3 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family AAA PF00004.29 KPA44794.1 - 1.4e-43 148.5 0.0 2.2e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA44794.1 - 1.6e-14 53.4 0.0 4.3e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KPA44794.1 - 1.8e-07 31.3 0.0 4.5e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 KPA44794.1 - 2.2e-07 30.7 2.3 5.8e-07 29.4 2.3 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KPA44794.1 - 2.8e-07 30.8 0.0 5.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KPA44794.1 - 4.1e-06 27.3 0.0 0.00011 22.6 0.1 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KPA44794.1 - 4.3e-05 23.8 0.3 0.018 15.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KPA44794.1 - 9.8e-05 22.1 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KPA44794.1 - 0.00046 20.7 0.1 0.015 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KPA44794.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KPA44794.1 - 0.0013 18.9 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KPA44794.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Prot_ATP_OB_N PF17758.1 KPA44794.1 - 0.0025 17.4 0.1 0.009 15.6 0.1 2.0 1 1 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain ATPase PF06745.13 KPA44794.1 - 0.0065 15.9 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 KPA44794.1 - 0.007 15.8 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KPA44794.1 - 0.0089 15.9 0.0 0.028 14.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KPA44794.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KPA44794.1 - 0.012 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KPA44794.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 KPA44794.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KPA44794.1 - 0.022 14.2 0.0 0.093 12.2 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KPA44794.1 - 0.025 14.3 0.1 0.064 13.0 0.0 1.8 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 KPA44794.1 - 0.026 14.2 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KPA44794.1 - 0.028 14.8 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KPA44794.1 - 0.03 14.3 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2072 PF09845.9 KPA44794.1 - 0.037 14.3 0.1 0.069 13.4 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_7 PF12775.7 KPA44794.1 - 0.05 13.1 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KPA44794.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HR1 PF02185.16 KPA44794.1 - 0.11 12.7 1.0 0.26 11.4 1.0 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_11 PF13086.6 KPA44794.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KPA44794.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KPA44794.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Y_phosphatase PF00102.27 KPA44795.1 - 5.8e-61 206.0 0.0 1.1e-52 178.9 0.0 3.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 KPA44795.1 - 1.3e-13 51.4 0.0 3.4e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 KPA44795.1 - 0.022 14.6 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KPA44795.1 - 0.044 13.8 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Tcp11 PF05794.13 KPA44796.1 - 2.1e-101 340.2 0.0 2.1e-101 340.2 0.0 2.7 3 0 0 3 3 3 1 T-complex protein 11 IQ PF00612.27 KPA44796.1 - 5.8 7.0 6.2 0.51 10.3 0.9 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif Peptidase_M1 PF01433.20 KPA44797.1 - 2.4e-80 269.2 2.2 3.4e-80 268.7 2.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KPA44797.1 - 1.8e-78 264.3 0.0 8e-78 262.1 0.0 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KPA44797.1 - 2.1e-49 168.3 2.4 2.7e-49 167.9 1.4 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KPA44797.1 - 0.1 12.6 0.2 0.67 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) DUF45 PF01863.17 KPA44797.1 - 2.1 8.4 4.9 0.82 9.7 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function DUF45 COesterase PF00135.28 KPA44798.1 - 2.2e-78 264.4 0.0 2.8e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA44798.1 - 0.00023 21.1 0.1 0.0019 18.1 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold P21-Arc PF04062.14 KPA44800.1 - 4.9e-73 244.9 0.0 5.6e-73 244.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit SSFA2_C PF14723.6 KPA44800.1 - 0.057 13.3 0.6 0.11 12.4 0.6 1.4 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Gcd10p PF04189.13 KPA44801.1 - 3.4e-124 413.9 0.0 4e-124 413.6 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family FMO-like PF00743.19 KPA44802.1 - 4.6e-26 91.3 0.1 1.3e-19 70.0 0.0 3.2 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPA44802.1 - 9.1e-13 48.1 0.0 6.3e-11 42.1 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA44802.1 - 3e-09 36.5 0.0 2.3e-08 33.6 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPA44802.1 - 4.5e-09 35.9 0.0 1.2e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA44802.1 - 1.5e-05 25.1 0.0 0.00078 19.5 0.0 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPA44802.1 - 2.4e-05 24.5 0.1 0.00026 21.1 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA44802.1 - 0.0007 19.3 0.5 0.0043 16.7 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KPA44802.1 - 0.025 13.8 0.7 0.14 11.4 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KPA44802.1 - 0.1 11.8 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KPA44802.1 - 0.11 13.1 0.1 4.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Psb28 PF03912.14 KPA44803.1 - 6.6 7.1 6.4 51 4.2 0.1 3.7 2 1 2 4 4 4 0 Psb28 protein PHO4 PF01384.20 KPA44804.1 - 1.1e-114 383.0 13.5 1.3e-114 382.8 13.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.16 KPA44805.1 - 3.6e-15 55.7 31.3 4.7e-15 55.4 25.9 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF2269 PF10027.9 KPA44805.1 - 0.019 15.0 1.3 0.079 13.0 0.0 2.4 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Sugar_tr PF00083.24 KPA44805.1 - 0.57 9.0 25.9 1.9e+02 0.6 25.4 3.0 1 1 0 1 1 1 0 Sugar (and other) transporter HlyIII PF03006.20 KPA44805.1 - 1.6 8.4 11.9 0.025 14.3 2.9 2.5 1 1 1 2 2 2 0 Haemolysin-III related GPI2 PF06432.11 KPA44805.1 - 5.1 6.4 6.3 9.6 5.6 0.0 3.1 2 2 1 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase SDA1 PF05285.12 KPA44806.1 - 2.1e-90 303.7 55.4 4.2e-90 302.7 47.2 2.6 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KPA44806.1 - 3.3e-24 85.0 0.1 1.1e-23 83.3 0.1 2.0 1 0 0 1 1 1 1 NUC130/3NT domain UNC45-central PF11701.8 KPA44806.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central adh_short PF00106.25 KPA44807.1 - 1.4e-17 63.8 0.1 2.8e-13 49.8 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA44807.1 - 4.6e-11 42.7 0.1 4.6e-10 39.4 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA44807.1 - 0.044 13.7 0.0 0.061 13.2 0.0 1.4 1 1 0 1 1 1 0 KR domain DUF5612 PF18462.1 KPA44807.1 - 0.098 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) Polysacc_synt_2 PF02719.15 KPA44807.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ank_2 PF12796.7 KPA44808.1 - 1.1e-11 45.1 0.2 5.2e-10 39.8 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KPA44808.1 - 2.4e-11 43.5 9.2 9.6e-06 25.8 0.2 4.0 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KPA44808.1 - 1.4e-10 41.2 4.0 2.7e-06 27.6 0.3 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPA44808.1 - 4.2e-09 36.8 0.6 7.3e-05 23.2 0.1 5.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA44808.1 - 9.7e-06 25.6 5.3 0.0011 19.3 0.0 4.8 5 1 0 5 5 5 1 Ankyrin repeat CxC7 PF18866.1 KPA44809.1 - 0.46 10.7 5.9 23 5.2 0.1 3.5 3 0 0 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases Arrestin_N PF00339.29 KPA44811.1 - 0.026 14.6 0.0 0.078 13.0 0.0 1.9 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KPA44811.1 - 0.052 14.0 0.4 0.44 11.0 0.1 2.6 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Mito_carr PF00153.27 KPA44812.1 - 4.8e-44 148.2 7.7 6.4e-16 58.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MBF1 PF08523.10 KPA44813.1 - 0.014 15.8 1.4 0.038 14.5 1.4 1.9 1 1 0 1 1 1 0 Multiprotein bridging factor 1 TPR_1 PF00515.28 KPA44814.1 - 0.13 12.1 0.1 0.36 10.7 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat CpXC PF14353.6 KPA44815.1 - 0.036 14.1 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 CpXC protein Zn_clus PF00172.18 KPA44816.1 - 5.6e-06 26.4 9.5 1.1e-05 25.4 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPA44817.1 - 3.9e-39 134.6 38.0 3.9e-39 134.6 38.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA44817.1 - 2.1e-14 52.9 13.6 2.1e-14 52.9 13.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPA44817.1 - 2.3e-12 46.5 15.2 2.3e-12 46.5 15.2 3.1 2 2 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 KPA44817.1 - 0.03 12.7 8.8 0.084 11.3 1.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector p450 PF00067.22 KPA44818.1 - 1e-15 57.5 0.0 2.4e-15 56.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 RdRP PF05183.12 KPA44819.1 - 7.3e-184 612.7 0.0 9.1e-184 612.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase FAD_binding_9 PF08021.11 KPA44819.1 - 0.15 12.3 0.0 3.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Abhydrolase_1 PF00561.20 KPA44820.1 - 5.8e-11 42.5 0.0 1.5e-10 41.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA44820.1 - 4.6e-08 34.0 0.0 8.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KPA44820.1 - 2.5e-07 29.7 0.0 3.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 KPA44820.1 - 2.2e-05 23.8 0.0 6.9e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EthD PF07110.11 KPA44820.1 - 8.6e-05 23.6 0.1 0.21 12.8 0.0 2.8 2 0 0 2 2 2 2 EthD domain Esterase PF00756.20 KPA44820.1 - 0.00013 21.7 0.0 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 Putative esterase DUF4286 PF14114.6 KPA44820.1 - 0.00021 21.7 0.1 0.065 13.7 0.0 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4286) Gpr1_Fun34_YaaH PF01184.19 KPA44821.1 - 5.2e-36 124.2 23.2 6.4e-36 123.9 23.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family F-box PF00646.33 KPA44823.1 - 1.1e-05 25.2 0.1 1.1e-05 25.2 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KPA44823.1 - 0.0051 16.7 0.1 0.015 15.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like zf-Mss51 PF13824.6 KPA44823.1 - 1.5 9.0 4.9 0.63 10.2 2.1 1.9 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 LRR_8 PF13855.6 KPA44824.1 - 1.9e-06 27.5 8.0 0.0011 18.6 0.1 4.7 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KPA44824.1 - 0.00029 21.1 8.7 0.031 14.7 0.2 4.9 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KPA44824.1 - 0.00033 20.5 1.8 0.021 14.9 0.2 3.0 2 0 0 2 2 2 1 Leucine Rich repeat LRR_1 PF00560.33 KPA44824.1 - 0.42 11.3 5.4 7.1 7.6 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat zf-C2H2 PF00096.26 KPA44825.1 - 1.1e-05 25.7 15.7 0.011 16.1 7.4 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPA44825.1 - 0.012 16.0 1.4 0.012 16.0 1.4 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPA44825.1 - 0.13 13.2 0.5 0.13 13.2 0.5 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 KPA44825.1 - 1.1 9.9 5.8 0.26 12.0 1.7 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KPA44825.1 - 6.2 6.9 8.7 0.61 10.2 0.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger Hexapep PF00132.24 KPA44826.1 - 0.00024 20.7 2.9 0.17 11.7 2.2 3.4 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KPA44826.1 - 0.0018 18.6 0.0 0.005 17.2 0.0 1.8 2 1 0 2 2 2 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KPA44826.1 - 0.0048 15.1 0.1 0.0069 14.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KPA44826.1 - 0.0062 15.5 0.4 0.0094 14.9 0.4 1.2 1 0 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.23 KPA44826.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase Spt20 PF12090.8 KPA44828.1 - 3.8e-45 154.3 0.1 3.8e-45 154.3 0.1 7.3 2 1 5 7 7 7 1 Spt20 family ATG27 PF09451.10 KPA44829.1 - 4.7e-93 311.9 0.0 5.4e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KPA44829.1 - 9.8e-06 25.7 0.0 0.011 15.8 0.0 2.8 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat ORC6 PF05460.13 KPA44829.1 - 0.11 11.8 0.3 0.14 11.4 0.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Aminotran_3 PF00202.21 KPA44830.1 - 5.7e-111 371.0 0.0 7.5e-111 370.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KPA44830.1 - 1.9e-07 30.6 0.0 5.9e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II NHase_beta PF02211.15 KPA44830.1 - 0.055 13.5 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Pyridoxal_deC PF00282.19 KPA44831.1 - 8.8e-77 258.3 0.0 1.1e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Abhydrolase_3 PF07859.13 KPA44832.1 - 4.3e-32 111.7 0.0 3.5e-21 76.0 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPA44832.1 - 0.0041 16.0 0.0 0.0064 15.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase SAM_decarbox PF01536.16 KPA44832.1 - 0.23 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase Cutinase PF01083.22 KPA44833.1 - 9.7e-49 165.7 4.7 1.2e-48 165.4 4.7 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPA44833.1 - 0.0022 17.6 0.3 0.0032 17.1 0.3 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KPA44833.1 - 0.0047 16.8 0.0 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 KPA44833.1 - 0.011 15.3 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 KPA44833.1 - 0.038 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DIMCO_N PF16844.5 KPA44833.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Peptidase_C2 PF00648.21 KPA44834.1 - 1.6e-63 214.5 1.3 1.6e-63 214.5 1.3 2.6 2 1 0 2 2 2 1 Calpain family cysteine protease NICE-1 PF15845.5 KPA44834.1 - 0.0044 17.8 0.0 0.013 16.2 0.0 1.7 1 0 0 1 1 1 1 Cysteine-rich C-terminal 1 family SARAF PF06682.12 KPA44834.1 - 0.062 12.9 8.2 0.032 13.9 5.3 2.0 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis ATP11 PF06644.11 KPA44834.1 - 0.2 11.4 0.0 0.2 11.4 0.0 2.9 3 0 0 3 3 3 0 ATP11 protein SKA1 PF07160.12 KPA44834.1 - 0.61 9.9 15.2 1.4 8.7 15.2 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 HAUS6_N PF14661.6 KPA44834.1 - 4.5 6.8 12.9 13 5.3 11.2 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus RNA_pol_3_Rpc31 PF11705.8 KPA44834.1 - 5.8 7.1 36.1 17 5.6 26.6 3.4 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4551 PF15087.6 KPA44834.1 - 6.9 5.4 16.2 13 4.5 16.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-TRAF PF02176.18 KPA44835.1 - 5.9e-11 42.9 25.6 7.6e-08 32.9 3.6 3.6 2 1 1 3 3 3 2 TRAF-type zinc finger zf-C3HC4 PF00097.25 KPA44835.1 - 9.4e-09 35.0 5.2 9.4e-09 35.0 5.2 3.5 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA44835.1 - 1.7e-08 34.2 6.2 1.7e-08 34.2 6.2 3.0 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA44835.1 - 4.7e-08 32.9 6.7 4.7e-08 32.9 6.7 3.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KPA44835.1 - 9.6e-08 31.8 2.2 9.6e-08 31.8 2.2 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPA44835.1 - 1.8e-07 31.2 7.2 1.8e-07 31.2 7.2 3.4 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KPA44835.1 - 1.2e-06 28.7 5.7 1.2e-06 28.7 5.7 3.5 2 1 1 3 3 1 1 Ring finger domain zf-RING_5 PF14634.6 KPA44835.1 - 3.4e-06 26.9 2.9 3.4e-06 26.9 2.9 3.4 3 1 1 4 4 4 1 zinc-RING finger domain zf-TRAF_2 PF15965.5 KPA44835.1 - 0.0002 21.8 9.0 0.0002 21.8 9.0 3.0 1 1 3 4 4 4 1 TRAF-like zinc-finger ALIX_LYPXL_bnd PF13949.6 KPA44835.1 - 0.035 13.4 0.8 0.057 12.7 0.8 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF1664 PF07889.12 KPA44835.1 - 1.1 9.2 3.1 18 5.4 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_6 PF14835.6 KPA44835.1 - 2.6 8.0 8.6 0.34 10.8 3.1 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Ufd2P_core PF10408.9 KPA44836.1 - 1.6e-210 701.0 5.8 2e-210 700.6 5.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KPA44836.1 - 2.4e-25 88.5 1.2 7.4e-25 86.9 1.2 1.9 1 0 0 1 1 1 1 U-box domain A_deaminase PF00962.22 KPA44837.1 - 1.1e-72 245.1 0.0 1.3e-72 244.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Fungal_trans PF04082.18 KPA44838.1 - 3.3e-27 95.2 0.3 3.3e-27 95.2 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA44838.1 - 6.8e-08 32.5 13.6 1.2e-07 31.7 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPO22 PF08631.10 KPA44839.1 - 9.6e-39 133.5 3.9 2.3e-34 119.1 0.0 3.2 2 1 1 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KPA44839.1 - 0.0059 16.9 4.1 0.0081 16.4 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Guanylate_cyc PF00211.20 KPA44839.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Sel1 PF08238.12 KPA44839.1 - 0.043 14.5 0.6 1.9 9.3 0.0 3.7 4 0 0 4 4 4 0 Sel1 repeat TPR_8 PF13181.6 KPA44839.1 - 0.1 12.8 0.4 2 8.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.18 KPA44840.1 - 7e-06 26.1 7.9 1.3e-05 25.2 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KPA44840.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 PAS fold Ald_Xan_dh_C2 PF02738.18 KPA44841.1 - 6.9e-207 688.3 0.4 9.8e-207 687.8 0.4 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KPA44841.1 - 2.8e-48 163.9 0.0 5.7e-48 162.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KPA44841.1 - 3.2e-32 111.2 0.1 9.8e-32 109.6 0.1 1.9 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KPA44841.1 - 3e-30 104.1 0.0 6.8e-30 102.9 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 KPA44841.1 - 2.8e-28 98.1 0.1 1.1e-27 96.2 0.1 2.1 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 KPA44841.1 - 1.9e-07 30.9 1.9 2.4e-07 30.6 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 KPA44841.1 - 0.0034 17.4 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 DUF218 domain Aminotran_1_2 PF00155.21 KPA44842.1 - 8.4e-70 235.7 0.0 9.6e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KPA44842.1 - 0.0024 16.5 0.0 0.0043 15.6 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KPA44842.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KPA44842.1 - 0.019 13.9 0.1 0.15 11.0 0.1 2.0 1 1 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 KPA44842.1 - 0.065 12.5 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase JmjC PF02373.22 KPA44843.1 - 7.5e-36 123.0 0.4 7.5e-36 123.0 0.4 2.8 4 0 0 4 4 4 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KPA44843.1 - 5.1e-21 74.9 5.9 1e-20 73.9 5.9 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KPA44843.1 - 1.9e-19 69.7 7.0 1.9e-19 69.7 7.0 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 KPA44843.1 - 3.9e-13 49.1 0.8 9.7e-13 47.8 0.8 1.8 1 0 0 1 1 1 1 jmjN domain PBP1_TM PF14812.6 KPA44843.1 - 0.85 10.0 11.1 0.51 10.7 4.7 3.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KPA44843.1 - 4.3 7.8 10.6 13 6.3 7.7 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain His_Phos_2 PF00328.22 KPA44844.1 - 1.3e-08 34.6 0.0 5.6e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HET PF06985.11 KPA44845.1 - 1.5e-33 116.2 0.1 2.5e-33 115.5 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) bZIP_1 PF00170.21 KPA44846.1 - 7.1e-09 35.6 9.9 1.8e-08 34.4 9.9 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPA44846.1 - 0.0012 18.8 10.8 0.0012 18.8 10.8 2.5 2 0 0 2 2 2 1 Basic region leucine zipper DivIC PF04977.15 KPA44846.1 - 7 6.5 13.0 1.1 9.1 0.8 2.6 2 0 0 2 2 2 0 Septum formation initiator Glyco_hydro_64 PF16483.5 KPA44847.1 - 4.4e-101 338.8 0.0 4.9e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Pro_isomerase PF00160.21 KPA44849.1 - 1e-47 162.4 0.0 2.1e-47 161.3 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KPA44849.1 - 2.8e-05 24.2 0.0 0.00012 22.2 0.0 2.1 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 KPA44849.1 - 0.00066 19.8 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein E2R135 PF11570.8 KPA44849.1 - 0.011 16.0 1.1 0.023 15.0 1.1 1.4 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Lung_7-TM_R PF06814.13 KPA44850.1 - 7e-71 238.9 16.5 8.6e-71 238.6 16.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4271 PF14093.6 KPA44850.1 - 1.7 8.5 20.2 4 7.3 12.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4271) Methyltransf_28 PF02636.17 KPA44851.1 - 1.1e-84 284.2 0.0 1.3e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 KPA44852.1 - 5e-63 212.9 0.0 6.7e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA44852.1 - 2.1e-29 102.6 0.0 3.7e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPA44852.1 - 0.00032 20.1 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KPA44852.1 - 0.0025 16.8 0.0 0.004 16.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KPA44852.1 - 0.004 16.5 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LpxI_C PF06230.11 KPA44852.1 - 0.077 12.9 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 LpxI C-terminal domain APH PF01636.23 KPA44852.1 - 0.081 12.8 0.1 0.081 12.8 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KPA44854.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF3854 PF12965.7 KPA44854.1 - 0.17 11.9 0.0 0.81 9.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) DCP2 PF05026.13 KPA44855.1 - 2e-31 108.1 0.9 3.5e-31 107.4 0.9 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KPA44855.1 - 6.9e-16 58.5 0.0 1.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.6 KPA44856.1 - 2.3e-35 121.1 0.5 2.9e-35 120.7 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) GAGE PF05831.11 KPA44856.1 - 3.4 8.2 9.7 7.2 7.2 5.9 2.7 2 1 1 3 3 3 0 GAGE protein Ribonuc_red_sm PF00268.21 KPA44857.1 - 1.8e-120 401.6 1.7 2.3e-120 401.3 1.7 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 KPA44858.1 - 4.4e-29 100.7 0.0 6.5e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ank_2 PF12796.7 KPA44859.1 - 2.2e-18 66.6 0.2 2.5e-07 31.2 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA44859.1 - 2.5e-16 59.8 1.8 3.4e-05 24.3 0.0 6.8 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA44859.1 - 1.7e-13 49.4 5.2 0.0021 18.4 0.1 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KPA44859.1 - 8e-13 48.2 8.3 0.0003 21.1 0.4 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KPA44859.1 - 5.6e-12 45.6 1.7 0.0041 17.4 0.0 5.9 5 1 1 6 6 6 3 Ankyrin repeats (many copies) F-box-like PF12937.7 KPA44859.1 - 0.00018 21.3 0.1 0.0032 17.3 0.1 2.3 2 0 0 2 2 2 1 F-box-like Reductase_C PF14759.6 KPA44859.1 - 0.14 12.7 0.0 0.96 10.1 0.0 2.4 3 0 0 3 3 3 0 Reductase C-terminal WD40 PF00400.32 KPA44860.1 - 9.2e-18 64.3 3.0 7e-07 29.8 0.2 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA44860.1 - 6.9e-07 29.5 0.0 0.2 12.0 0.0 4.5 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain EAF PF09816.9 KPA44860.1 - 0.0057 17.0 0.2 0.021 15.2 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Mito_carr PF00153.27 KPA44861.1 - 5.2e-57 189.8 1.6 3.8e-19 68.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MotA_ExbB PF01618.16 KPA44861.1 - 0.09 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family CTU2 PF10288.9 KPA44862.1 - 9.7e-10 38.7 0.0 8.3e-08 32.5 0.0 2.6 1 1 1 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 PutA_N PF18083.1 KPA44862.1 - 0.003 17.6 0.0 0.16 12.0 0.0 3.0 3 0 0 3 3 3 1 Proline utilization A N-terminal domain DZR PF12773.7 KPA44862.1 - 0.061 13.4 3.2 0.16 12.0 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon APH PF01636.23 KPA44863.1 - 1.8e-08 34.6 0.1 2.2e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPA44863.1 - 0.007 16.0 0.0 0.015 14.9 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 KPA44863.1 - 0.033 13.5 0.0 0.044 13.1 0.0 1.5 1 1 0 1 1 1 0 Ecdysteroid kinase PH PF00169.29 KPA44864.1 - 1.2e-25 90.0 1.4 4.4e-16 59.3 0.4 2.3 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 KPA44864.1 - 3.1e-12 46.9 4.5 7.4e-07 29.6 1.9 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KPA44864.1 - 2.2e-09 37.7 5.2 0.00015 22.1 1.5 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KPA44864.1 - 0.00017 21.8 0.3 0.00038 20.7 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KPA44864.1 - 0.0011 19.1 1.5 0.017 15.2 0.4 2.7 2 2 0 2 2 2 1 PH domain PH_13 PF16652.5 KPA44864.1 - 0.009 15.8 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Med2 PF11214.8 KPA44865.1 - 0.1 12.8 1.3 0.29 11.3 0.2 2.1 2 0 0 2 2 2 0 Mediator complex subunit 2 RRM_1 PF00076.22 KPA44866.1 - 2.2e-60 200.4 0.0 4.7e-21 74.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPA44866.1 - 1.9e-09 37.2 0.0 4.6e-05 23.0 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPA44866.1 - 2.3e-09 37.0 0.0 0.0089 15.9 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KPA44866.1 - 1.2e-05 25.2 0.1 0.51 10.4 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KPA44866.1 - 0.00094 19.3 0.0 1 9.5 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif Cas_Cas2CT1978 PF09707.10 KPA44866.1 - 0.0011 18.9 0.0 0.61 10.2 0.0 2.6 3 0 0 3 3 3 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_8 PF11835.8 KPA44866.1 - 0.0022 18.1 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 2 RRM-like domain Limkain-b1 PF11608.8 KPA44866.1 - 0.014 15.4 0.1 6.1 7.0 0.0 3.2 3 0 0 3 3 3 0 Limkain b1 RRM_3 PF08777.11 KPA44866.1 - 0.065 13.3 0.0 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif SET_assoc PF11767.8 KPA44866.1 - 0.078 12.6 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Pkinase PF00069.25 KPA44867.1 - 2.7e-50 171.2 0.1 1.3e-49 169.0 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA44867.1 - 2.7e-23 82.6 0.0 5.4e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPA44867.1 - 0.00034 20.6 0.1 0.00034 20.6 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KPA44867.1 - 0.0029 17.2 0.2 0.0073 15.9 0.2 1.6 1 1 0 1 1 1 1 RIO1 family Btz PF09405.10 KPA44868.1 - 0.021 15.1 0.1 0.039 14.2 0.1 1.5 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.22 KPA44868.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PPR_2 PF13041.6 KPA44869.1 - 1.8e-19 69.7 0.9 1.2e-12 47.8 0.0 4.1 4 1 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 KPA44869.1 - 7e-08 32.4 0.0 0.018 15.1 0.0 3.4 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 KPA44869.1 - 4e-07 29.8 0.4 0.11 12.8 0.0 4.8 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 KPA44869.1 - 8.3e-07 28.6 2.0 2.2e-05 23.9 0.3 2.2 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KPA44869.1 - 0.00033 20.3 0.9 17 5.2 0.0 4.9 5 0 0 5 5 5 1 PPR repeat ATP13 PF12921.7 KPA44869.1 - 0.0083 16.0 0.4 1.9 8.4 0.0 2.9 3 0 0 3 3 3 1 Mitochondrial ATPase expression HHH_2 PF12826.7 KPA44869.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif PfUIS3 PF11567.8 KPA44869.1 - 0.37 11.2 2.2 2.7 8.4 0.1 2.9 2 1 1 3 3 3 0 Plasmodium falciparum UIS3 membrane protein DNA_pol_B PF00136.21 KPA44871.1 - 6e-117 391.1 0.2 9.5e-117 390.5 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KPA44871.1 - 6.2e-68 228.2 1.8 9.6e-68 227.6 0.8 1.9 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KPA44871.1 - 5.1e-42 144.2 0.0 1.2e-41 143.0 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KPA44871.1 - 7e-25 86.9 9.5 7e-25 86.9 9.5 2.9 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KPA44871.1 - 0.0095 14.8 0.2 0.025 13.4 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral MIF4G PF02854.19 KPA44872.1 - 3.1e-52 177.3 0.0 4.9e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KPA44872.1 - 9.5e-24 83.4 1.5 4.2e-23 81.3 1.5 2.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 DUF4148 PF13663.6 KPA44872.1 - 0.012 15.8 2.8 0.3 11.3 0.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Aquarius_N PF16399.5 KPA44873.1 - 0 1104.7 0.0 0 1104.3 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KPA44873.1 - 1.4e-27 96.6 0.0 3.8e-27 95.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KPA44873.1 - 7.6e-21 75.1 0.0 8.8e-20 71.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPA44873.1 - 7.2e-09 35.6 0.0 3.7e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KPA44873.1 - 3.9e-06 27.0 0.0 8.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KPA44873.1 - 6.7e-06 26.5 0.0 1.8e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KPA44873.1 - 0.0031 16.9 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KPA44873.1 - 0.0035 17.7 0.0 0.022 15.2 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 KPA44873.1 - 0.0048 16.7 0.2 0.29 10.8 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KPA44873.1 - 0.0088 16.5 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA44873.1 - 0.01 16.1 0.2 0.08 13.2 0.1 2.4 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 KPA44873.1 - 0.04 13.7 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF2075 PF09848.9 KPA44873.1 - 0.045 13.0 1.2 0.053 12.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KPA44873.1 - 0.085 12.4 0.2 0.26 10.7 0.0 1.9 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain NACHT PF05729.12 KPA44873.1 - 0.19 11.6 0.5 1 9.3 0.0 2.5 3 0 0 3 3 3 0 NACHT domain PIF1 PF05970.14 KPA44873.1 - 0.21 10.7 0.0 3.5 6.7 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase RecA PF00154.21 KPA44873.1 - 0.21 11.0 0.0 0.37 10.2 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein efThoc1 PF11957.8 KPA44874.1 - 1.3e-139 466.1 1.7 1.8e-139 465.6 1.7 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 KPA44874.1 - 6.4e-31 107.4 0.0 1.2e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 KPA44874.1 - 0.022 14.8 0.1 0.066 13.3 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase eIF-5_eIF-2B PF01873.17 KPA44875.1 - 1.2e-40 138.0 0.0 1.1e-39 135.0 0.0 2.1 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 KPA44875.1 - 1.2e-22 79.8 0.1 4.2e-22 78.1 0.1 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon p450 PF00067.22 KPA44876.1 - 2.7e-42 145.1 0.1 6.5e-37 127.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 CdvA PF18822.1 KPA44878.1 - 0.086 12.7 0.0 0.086 12.7 0.0 2.6 3 0 0 3 3 3 0 CdvA-like coiled-coil domain eIF-6 PF01912.18 KPA44879.1 - 1.9e-80 268.9 0.8 2.6e-80 268.5 0.8 1.2 1 0 0 1 1 1 1 eIF-6 family HupE_UreJ PF04955.12 KPA44879.1 - 0.11 11.9 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 HupE / UreJ protein Methyltransf_31 PF13847.6 KPA44880.1 - 5.1e-15 55.6 0.0 7.6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA44880.1 - 1.1e-07 32.4 0.0 2.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA44880.1 - 2.1e-06 28.3 0.0 4.1e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA44880.1 - 4.7e-06 26.5 0.0 1.6e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 KPA44880.1 - 4.8e-06 26.3 0.0 7.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.12 KPA44880.1 - 2e-05 25.2 0.0 3.9e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA44880.1 - 0.00083 18.9 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KPA44880.1 - 0.0017 17.7 0.0 0.02 14.2 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KPA44880.1 - 0.0054 16.9 0.0 0.0069 16.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase AdoMet_MTase PF07757.13 KPA44880.1 - 0.014 15.8 0.0 0.038 14.3 0.0 1.9 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KPA44880.1 - 0.017 15.1 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KPA44880.1 - 0.086 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.11 KPA44880.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) HEAT PF02985.22 KPA44881.1 - 4e-39 129.3 18.5 0.015 15.5 0.1 13.2 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 KPA44881.1 - 2.2e-35 120.9 8.9 9.5e-11 42.0 0.0 8.4 4 2 4 8 8 8 8 HEAT repeats HEAT_EZ PF13513.6 KPA44881.1 - 7.2e-14 51.9 3.9 0.022 15.2 0.0 7.9 8 1 1 9 9 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KPA44881.1 - 7.1e-12 45.8 3.7 0.019 15.6 0.1 7.7 5 2 4 9 9 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KPA44881.1 - 3.9e-11 43.3 12.2 0.00023 21.2 0.2 6.4 5 1 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KPA44881.1 - 5.8e-09 35.0 7.1 0.013 14.1 0.1 5.2 4 1 2 6 6 6 3 Adaptin N terminal region RTP1_C1 PF10363.9 KPA44881.1 - 1.4e-05 25.3 7.8 0.29 11.3 0.3 5.2 5 1 0 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KPA44881.1 - 0.00014 21.5 3.4 1.1 8.8 0.1 4.2 3 3 2 5 5 5 2 CLASP N terminal Ecm29 PF13001.7 KPA44881.1 - 0.0023 16.7 2.7 0.087 11.5 0.0 3.6 4 1 1 5 5 5 1 Proteasome stabiliser Proteasom_PSMB PF10508.9 KPA44881.1 - 0.1 11.1 4.5 0.39 9.2 0.1 2.4 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Arm PF00514.23 KPA44881.1 - 3 8.0 10.1 3.1 8.0 0.0 4.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat API5 PF05918.11 KPA44881.1 - 3.3 6.4 5.5 1.7 7.3 0.1 3.2 4 1 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) tRNA_synthFbeta PF17759.1 KPA44882.1 - 7.7e-47 159.5 0.0 1.2e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KPA44882.1 - 1.7e-32 111.5 0.3 2.3e-31 107.8 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KPA44882.1 - 5.5e-24 84.8 0.1 8.7e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KPA44882.1 - 5.7e-17 61.8 0.0 1e-13 51.3 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain SPRY PF00622.28 KPA44882.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 SPRY domain Myotub-related PF06602.14 KPA44883.1 - 2.9e-149 496.8 0.1 3.6e-149 496.5 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KPA44883.1 - 0.086 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family LytB_WW PF18342.1 KPA44883.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Endo-beta-N-acetylglucosaminidase LytB WW domain Ribosomal_S3_C PF00189.20 KPA44884.1 - 8.3e-25 87.1 0.2 4.3e-24 84.8 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KPA44884.1 - 5.6e-12 45.3 0.1 1.1e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 KPA44884.1 - 0.097 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 KPA44884.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Coilin N-terminus Mg_trans_NIPA PF05653.14 KPA44885.1 - 2.6e-104 348.5 11.3 3e-104 348.3 11.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KPA44885.1 - 6e-05 23.2 6.2 6e-05 23.2 6.2 3.8 3 1 0 3 3 3 1 EamA-like transporter family DUF2530 PF10745.9 KPA44885.1 - 0.11 12.8 0.5 3.2 8.1 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) DUF2420 PF10336.9 KPA44886.1 - 1.1e-11 44.7 0.3 1.9e-11 43.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 KPA44887.1 - 3.4e-16 59.4 0.0 5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KPA44887.1 - 3.1e-09 36.9 0.1 5e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KPA44887.1 - 0.00021 20.9 0.0 0.00077 19.0 0.0 1.7 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain RPM2 PF08579.11 KPA44887.1 - 0.015 15.7 0.3 0.03 14.7 0.3 1.5 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) ANAPC4 PF12896.7 KPA44888.1 - 1.6e-68 230.2 0.1 2.5e-68 229.6 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KPA44888.1 - 8.8e-13 48.4 0.0 1.6e-11 44.3 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Gtr1_RagA PF04670.12 KPA44889.1 - 7.3e-70 234.9 0.2 8.9e-70 234.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KPA44889.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPA44889.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Roc PF08477.13 KPA44889.1 - 0.021 15.0 0.0 0.043 14.0 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KPA44889.1 - 0.032 14.3 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KPA44889.1 - 0.033 14.6 0.0 0.079 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MIF PF01187.18 KPA44890.1 - 1.7e-06 28.3 0.0 2.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) LCAT PF02450.15 KPA44893.1 - 0.035 13.3 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase His_Phos_2 PF00328.22 KPA44894.1 - 2.7e-15 56.6 0.0 6.9e-14 52.0 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RRM_1 PF00076.22 KPA44895.1 - 5.5e-36 122.2 0.0 2.1e-11 43.5 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPA44895.1 - 6.1e-15 54.9 0.0 0.026 14.4 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 KPA44895.1 - 4.3e-08 32.7 6.2 4.3e-08 32.7 6.2 3.2 2 1 0 2 2 2 1 Putative RRM domain RRM_7 PF16367.5 KPA44895.1 - 0.00011 22.2 0.0 0.31 11.2 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif DUF4523 PF15023.6 KPA44895.1 - 0.00014 21.8 0.0 0.098 12.5 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) RRM_Rrp7 PF17799.1 KPA44895.1 - 0.013 15.3 0.0 1.3 8.8 0.0 3.5 3 1 1 4 4 4 0 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 KPA44895.1 - 0.016 15.2 0.0 5.7 7.0 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KPA44895.1 - 0.022 14.8 0.1 0.38 10.8 0.1 2.6 3 0 0 3 3 3 0 RNA binding motif Arginase PF00491.21 KPA44896.1 - 4.6e-93 311.8 0.0 5.8e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KPA44896.1 - 0.0054 17.0 0.1 0.0079 16.4 0.1 1.4 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.22 KPA44897.1 - 9.2e-53 178.2 0.0 1.1e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA44897.1 - 5e-19 68.7 0.0 6.8e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA44897.1 - 9.6e-07 28.4 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPA44897.1 - 0.18 11.4 0.0 0.87 9.1 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain MFS_1 PF07690.16 KPA44898.1 - 2.6e-37 128.6 29.6 4.5e-37 127.8 26.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA44898.1 - 2e-07 29.9 10.4 2.1e-06 26.6 0.6 2.7 2 2 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 KPA44898.1 - 5.7e-06 24.9 5.0 0.00036 19.0 2.0 2.9 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KPA44898.1 - 1.1 8.1 21.1 0.057 12.3 6.8 3.4 3 0 0 3 3 3 0 MFS_1 like family CDC45 PF02724.14 KPA44898.1 - 1.1 7.5 3.5 1.7 6.9 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein COX7C PF02935.16 KPA44898.1 - 7.3 6.9 6.8 4 7.8 2.1 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Pyr_redox_dim PF02852.22 KPA44899.1 - 2.2e-20 72.9 0.0 2.8e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DUF3669 PF12417.8 KPA44900.1 - 1.3e-19 70.2 0.1 3.2e-19 68.9 0.1 1.8 1 0 0 1 1 1 1 Zinc finger protein pPIWI_RE_REase PF18154.1 KPA44900.1 - 0.086 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 REase associating with pPIWI_RE DUF4667 PF15700.5 KPA44900.1 - 2.2 8.3 9.7 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Voltage_CLC PF00654.20 KPA44901.1 - 7.6e-87 291.8 27.8 7.6e-87 291.8 27.8 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KPA44901.1 - 0.021 15.2 0.0 0.22 12.0 0.0 2.3 2 0 0 2 2 2 0 CBS domain Neurochondrin PF05536.11 KPA44902.1 - 2.7e-88 296.9 4.7 3.8e-88 296.4 4.7 1.2 1 0 0 1 1 1 1 Neurochondrin RIX1 PF08167.12 KPA44902.1 - 0.046 13.5 3.8 0.077 12.7 0.5 3.0 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis DNA_ligase_A_M PF01068.21 KPA44903.1 - 4.3e-61 206.1 0.7 1.9e-48 164.9 0.2 2.5 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KPA44903.1 - 3.5e-43 147.9 0.0 8.1e-43 146.7 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KPA44903.1 - 7.6e-30 103.4 0.5 1.3e-28 99.5 0.0 3.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KPA44903.1 - 3.2e-05 24.3 0.2 5.2e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 KPA44903.1 - 0.081 13.0 0.1 21 5.2 0.1 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain E1_dh PF00676.20 KPA44904.1 - 5.1e-114 380.3 0.7 6.7e-114 379.9 0.7 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KPA44904.1 - 0.0014 17.9 0.5 0.0028 16.9 0.2 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.32 KPA44905.1 - 2.8e-37 126.1 23.5 3.9e-07 30.6 0.2 7.2 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 KPA44905.1 - 1.3e-12 47.3 0.6 2.7e-12 46.4 0.6 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KPA44905.1 - 1.1e-09 38.5 1.2 0.2 12.0 0.0 6.0 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA44905.1 - 1.8e-06 26.9 6.7 0.32 9.6 0.1 5.7 1 1 4 6 6 6 2 Nucleoporin Nup120/160 F-box PF00646.33 KPA44905.1 - 4.9e-06 26.3 2.1 1e-05 25.3 2.1 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KPA44905.1 - 0.00034 20.1 0.0 0.074 12.4 0.0 2.8 2 1 1 3 3 3 1 WD40-like domain PALB2_WD40 PF16756.5 KPA44905.1 - 0.012 14.6 2.4 2.3 7.1 0.0 3.6 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 KPA44905.1 - 0.034 14.6 2.0 46 4.7 0.0 4.8 5 0 0 5 5 5 0 PQQ-like domain PQQ_2 PF13360.6 KPA44905.1 - 0.036 13.7 4.6 0.088 12.4 1.0 3.0 1 1 1 2 2 2 0 PQQ-like domain F-box_5 PF18511.1 KPA44905.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 F-box zf_C2HC_14 PF18574.1 KPA44905.1 - 0.14 12.0 0.1 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 C2HC Zing finger domain EH_Signature PF15611.6 KPA44905.1 - 0.14 11.6 0.0 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 EH_Signature domain Zip PF02535.22 KPA44906.1 - 9.9e-33 113.7 34.3 2.8e-31 109.0 34.3 3.2 1 1 0 1 1 1 1 ZIP Zinc transporter DNA_pol_phi PF04931.13 KPA44906.1 - 0.98 7.4 6.2 1.4 7.0 6.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 KPA44906.1 - 5.2 5.7 5.8 0.24 10.1 0.0 1.7 2 0 0 2 2 2 0 Presenilin 4HB_MCP_1 PF12729.7 KPA44907.1 - 0.27 10.8 1.7 0.39 10.2 1.7 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction BAR_2 PF10455.9 KPA44908.1 - 0.076 12.1 2.2 0.11 11.7 2.2 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Phasin PF05597.11 KPA44908.1 - 0.26 11.3 3.3 1.4 9.0 0.3 2.7 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Rep_4 PF05797.11 KPA44908.1 - 0.93 8.5 2.1 1.4 8.0 2.1 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) CRIM PF16978.5 KPA44909.1 - 8.3e-44 149.2 0.0 1.7e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KPA44909.1 - 3.3e-33 114.2 0.0 6.7e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KPA44909.1 - 0.033 14.4 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 TUG ubiquitin-like domain PRCC PF10253.9 KPA44910.1 - 2.3e-31 110.3 9.7 2.3e-31 110.3 9.7 3.8 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting HLH PF00010.26 KPA44911.1 - 0.046 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain DUF3517 PF12030.8 KPA44912.1 - 5.6e-93 311.5 0.0 1.2e-92 310.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 KPA44912.1 - 1.3e-42 146.1 1.8 2.8e-42 145.0 1.8 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPA44912.1 - 1.6e-24 87.1 2.0 3.4e-24 86.0 2.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_P_pop3 PF08228.11 KPA44913.1 - 2.5e-09 37.4 0.0 8.8e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 TcdB_N PF12918.7 KPA44913.1 - 0.15 12.4 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain NOC3p PF07540.11 KPA44915.1 - 5.5e-29 100.5 0.1 2.6e-28 98.3 0.1 2.3 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 KPA44915.1 - 4.6e-27 95.1 0.1 4.6e-27 95.1 0.1 2.8 2 1 0 2 2 2 1 CBF/Mak21 family CENP-B_dimeris PF09026.10 KPA44915.1 - 0.024 15.0 5.0 0.024 15.0 5.0 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Brix PF04427.18 KPA44916.1 - 2.6e-24 86.4 0.1 4e-24 85.8 0.1 1.3 1 0 0 1 1 1 1 Brix domain GDP_Man_Dehyd PF16363.5 KPA44917.1 - 1.8e-68 231.4 0.0 2.1e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KPA44917.1 - 7.4e-55 186.0 0.0 9.1e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPA44917.1 - 3.1e-19 69.2 0.0 3.2e-18 65.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KPA44917.1 - 4.8e-18 65.1 0.0 6.4e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KPA44917.1 - 6.9e-17 61.5 0.0 8.3e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KPA44917.1 - 3.1e-16 59.3 0.1 3.5e-15 55.9 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KPA44917.1 - 6.3e-07 29.5 0.0 9.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KPA44917.1 - 0.072 12.5 0.0 1.3 8.5 0.1 2.3 3 0 0 3 3 3 0 short chain dehydrogenase Methyltransf_23 PF13489.6 KPA44918.1 - 7.8e-16 58.3 0.0 1.4e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA44918.1 - 1.8e-09 38.2 0.0 3.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA44918.1 - 2.1e-08 34.1 0.0 4.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA44918.1 - 1.3e-07 32.2 0.0 3.7e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA44918.1 - 0.00024 21.7 0.0 0.00051 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KPA44918.1 - 0.0013 18.2 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KPA44918.1 - 0.0021 17.6 0.0 0.0063 16.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KPA44918.1 - 0.0021 17.4 0.1 0.01 15.2 0.0 2.1 3 0 0 3 3 3 1 O-methyltransferase domain Ubie_methyltran PF01209.18 KPA44918.1 - 0.0024 17.2 0.0 0.0052 16.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KPA44918.1 - 0.02 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KPA44918.1 - 0.05 13.0 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KPA44918.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LAT PF15234.6 KPA44918.1 - 2.3 7.9 8.0 4 7.1 8.0 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells Pep3_Vps18 PF05131.14 KPA44919.1 - 1.9e-43 147.8 0.1 3.6e-43 146.9 0.1 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KPA44919.1 - 6.8e-10 39.0 0.7 4.8e-07 29.8 0.0 3.3 3 0 0 3 3 3 1 Region in Clathrin and VPS DUF2175 PF09943.9 KPA44919.1 - 4.3e-05 23.7 0.2 0.00087 19.5 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) Zn_ribbon_17 PF17120.5 KPA44919.1 - 0.0014 18.2 0.1 0.0034 17.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KPA44919.1 - 0.0054 16.6 0.8 0.014 15.2 0.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPA44919.1 - 0.0062 16.5 0.4 0.0062 16.5 0.4 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KPA44919.1 - 0.0083 15.9 1.9 0.0083 15.9 1.9 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 KPA44919.1 - 0.038 14.3 0.6 0.1 13.0 0.6 1.7 1 0 0 1 1 1 0 Ring finger domain Vps39_2 PF10367.9 KPA44919.1 - 0.039 14.4 0.0 0.089 13.2 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 KPA44919.1 - 0.04 14.0 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KPA44919.1 - 0.053 13.8 0.2 0.13 12.6 0.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Nup96 PF12110.8 KPA44919.1 - 0.11 11.6 0.1 11 5.0 0.0 2.3 2 0 0 2 2 2 0 Nuclear protein 96 zf-C3H2C3 PF17122.5 KPA44919.1 - 0.82 9.8 6.2 0.15 12.1 1.9 2.0 2 0 0 2 2 2 0 Zinc-finger Nup54_57_C PF18570.1 KPA44919.1 - 1.9 8.2 3.4 1.4 8.6 0.0 2.5 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain ATP-synt_C PF00137.21 KPA44920.1 - 3.8e-28 97.6 29.4 1.2e-19 70.4 13.7 2.2 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 KPA44920.1 - 0.87 9.3 3.4 25 4.6 0.6 2.6 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Asp PF00026.23 KPA44921.1 - 5e-75 252.8 2.9 6.7e-75 252.4 2.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA44921.1 - 3.8e-16 59.8 0.5 1.8e-07 31.6 0.0 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal PBP PF01161.20 KPA44921.1 - 9.2e-16 58.4 0.0 1.8e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TAXi_C PF14541.6 KPA44921.1 - 0.0012 18.7 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KPA44921.1 - 0.0036 17.9 1.0 9 7.0 0.1 3.8 3 1 0 3 3 3 2 Aspartyl protease 2OG-FeII_Oxy_3 PF13640.6 KPA44922.1 - 1.8e-08 35.2 0.1 3.2e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KPA44923.1 - 4.2e-13 48.9 0.0 8.5e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA44923.1 - 3.3e-10 39.9 11.7 6.2e-10 39.0 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferric_reduct PF01794.19 KPA44924.1 - 1.1e-23 83.7 9.7 1.1e-23 83.7 9.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPA44924.1 - 1.2e-16 61.2 0.0 1.8e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPA44924.1 - 1.2e-09 38.3 0.0 2.9e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KPA44924.1 - 3.9e-08 33.9 0.0 9.2e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ctr PF04145.15 KPA44925.1 - 9.6e-36 123.6 3.3 1.2e-35 123.3 3.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Na_H_antiporter PF03553.14 KPA44925.1 - 0.0023 17.2 3.1 0.0031 16.8 3.1 1.2 1 0 0 1 1 1 1 Na+/H+ antiporter family SAM_1 PF00536.30 KPA44926.1 - 2.1e-07 31.3 0.1 4.7e-07 30.2 0.1 1.6 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KPA44926.1 - 4.4e-06 26.7 0.2 1.4e-05 25.1 0.2 1.8 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) HEAT_PBS PF03130.16 KPA44926.1 - 0.0094 16.5 0.8 7.7 7.5 0.0 2.4 2 0 0 2 2 2 2 PBS lyase HEAT-like repeat DUF3767 PF12597.8 KPA44928.1 - 1.9e-37 127.2 0.8 2.2e-37 126.9 0.2 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) CI-B14_5a PF07347.12 KPA44928.1 - 0.0065 16.3 0.8 0.014 15.3 0.8 1.5 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF2205 PF10224.9 KPA44928.1 - 0.0072 16.3 3.3 0.011 15.7 3.3 1.3 1 0 0 1 1 1 1 Short coiled-coil protein DUF1744 PF08490.12 KPA44929.1 - 4.8e-153 509.5 0.0 7e-153 508.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KPA44929.1 - 6.3e-74 249.1 0.1 9.8e-74 248.5 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KPA44929.1 - 6.8e-16 58.0 0.1 5e-13 48.6 0.1 3.5 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KPA44929.1 - 3.8e-09 36.5 0.1 1e-08 35.2 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KPA44929.1 - 5.1e-06 26.6 0.0 1.8e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily FOXP-CC PF16159.5 KPA44930.1 - 0.00031 21.3 5.1 4.1 8.1 0.4 3.5 1 1 2 3 3 3 3 FOXP coiled-coil domain zf-C2H2 PF00096.26 KPA44930.1 - 0.0082 16.6 6.0 1 10.0 0.4 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA44930.1 - 0.08 13.8 13.0 1.5 9.9 0.3 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger CUE PF02845.16 KPA44931.1 - 3e-10 39.6 0.1 6e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 CUE domain NOA36 PF06524.12 KPA44931.1 - 0.14 11.5 4.1 0.24 10.7 4.1 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoporin_FG PF13634.6 KPA44932.1 - 5.7e-11 43.1 136.9 8.4e-05 23.4 21.3 7.5 2 2 4 6 6 6 4 Nucleoporin FG repeat region zf-CCCH_4 PF18044.1 KPA44932.1 - 1.6e-06 27.8 6.2 2.3e-06 27.3 4.9 1.9 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KPA44932.1 - 2.8e-05 24.0 8.4 6e-05 23.0 8.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KPA44932.1 - 0.00044 20.1 3.4 0.00094 19.0 3.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KPA44932.1 - 0.046 14.4 0.3 0.09 13.5 0.3 1.5 1 0 0 1 1 1 0 Torus domain p450 PF00067.22 KPA44933.1 - 2.4e-64 217.8 0.0 3.1e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Frag1 PF10277.9 KPA44934.1 - 4.3e-37 127.8 7.5 4.3e-37 127.8 7.5 2.7 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KPA44934.1 - 0.058 12.9 0.0 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family U3_assoc_6 PF08640.11 KPA44935.1 - 2.4e-26 91.6 1.6 1.9e-25 88.7 0.4 2.7 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KPA44935.1 - 0.00062 20.4 0.1 0.27 12.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KPA44935.1 - 0.00071 18.8 1.4 0.0013 17.9 1.2 1.7 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference Suf PF05843.14 KPA44935.1 - 0.048 13.6 0.0 0.19 11.7 0.0 2.0 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) Radical_SAM PF04055.21 KPA44935.1 - 0.14 12.6 0.2 0.76 10.1 0.1 2.1 2 0 0 2 2 2 0 Radical SAM superfamily ARID PF01388.21 KPA44936.1 - 1.9e-17 63.7 1.8 4.4e-17 62.5 0.0 2.6 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain DUF2407_C PF13373.6 KPA44936.1 - 0.017 15.3 1.8 0.017 15.3 1.8 2.0 2 0 0 2 2 2 0 DUF2407 C-terminal domain Img2 PF05046.14 KPA44937.1 - 2.5e-20 72.5 0.1 3.9e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.10 KPA44938.1 - 1.9e-46 157.8 1.7 4.2e-46 156.7 1.7 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KPA44938.1 - 3.3e-12 46.8 0.0 9.4e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.6 KPA44938.1 - 0.068 14.0 1.6 11 7.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC1 PF12859.7 KPA44939.1 - 2.1e-38 131.8 0.2 2.1e-38 131.8 0.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KPA44939.1 - 0.017 15.5 1.6 8.1 7.1 0.0 4.4 5 0 0 5 5 5 0 Proteasome/cyclosome repeat Clathrin PF00637.20 KPA44940.1 - 1.3e-19 70.5 2.0 2.3e-18 66.5 0.7 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_7 PF13176.6 KPA44940.1 - 0.0063 16.5 0.2 0.051 13.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat WD40_like PF17005.5 KPA44940.1 - 0.036 13.4 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain TPR_2 PF07719.17 KPA44940.1 - 0.056 13.6 0.1 0.27 11.4 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat NBP1 PF08537.10 KPA44940.1 - 0.066 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Vps39_2 PF10367.9 KPA44940.1 - 0.08 13.4 0.0 0.3 11.6 0.0 2.0 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 TPR_12 PF13424.6 KPA44940.1 - 0.14 12.5 3.6 0.66 10.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KPA44940.1 - 0.27 11.5 1.2 0.64 10.3 0.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.6 KPA44940.1 - 0.89 9.6 2.9 2.4 8.2 2.9 1.7 1 1 0 1 1 1 0 zinc-RING finger domain MGC-24 PF05283.11 KPA44942.1 - 3.3 8.1 7.8 5.9 7.3 7.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GatB_N PF02934.15 KPA44943.1 - 7.6e-100 333.8 0.0 1e-99 333.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KPA44943.1 - 3e-11 43.4 0.3 8.5e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 GatB domain MGC-24 PF05283.11 KPA44944.1 - 0.00081 19.9 0.3 0.0019 18.6 0.3 1.6 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Adeno_E3_CR2 PF02439.15 KPA44944.1 - 0.0039 16.9 1.0 0.0061 16.3 1.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4448 PF14610.6 KPA44944.1 - 0.014 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PARM PF17061.5 KPA44944.1 - 0.015 15.5 2.3 0.015 15.5 2.3 2.8 1 1 0 3 3 3 0 PARM SKG6 PF08693.10 KPA44944.1 - 0.031 13.7 2.4 0.061 12.7 2.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 KPA44944.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Podoplanin TMEM132D_C PF15706.5 KPA44944.1 - 0.051 13.4 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Sensor PF13796.6 KPA44944.1 - 0.061 13.4 0.1 0.099 12.7 0.1 1.3 1 0 0 1 1 1 0 Putative sensor Syndecan PF01034.20 KPA44944.1 - 0.062 13.2 0.4 0.1 12.5 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain Orf78 PF06024.12 KPA44944.1 - 0.2 12.0 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DnaJ PF00226.31 KPA44945.1 - 6.6e-08 32.6 0.8 1.2e-07 31.8 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain Gpr1_Fun34_YaaH PF01184.19 KPA44946.1 - 2.5e-53 180.8 16.7 3.5e-53 180.3 16.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2254 PF10011.9 KPA44946.1 - 0.012 14.4 1.5 0.012 14.4 1.5 1.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2254) PhoLip_ATPase_C PF16212.5 KPA44946.1 - 0.045 13.5 7.1 0.068 12.9 7.1 1.2 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal YrhC PF14143.6 KPA44946.1 - 0.34 11.0 4.8 1.2 9.3 4.8 1.9 1 0 0 1 1 1 0 YrhC-like protein S_4TM PF18159.1 KPA44946.1 - 0.69 9.2 2.5 1.2 8.4 2.5 1.3 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Apolipoprotein PF01442.18 KPA44947.1 - 0.0012 18.7 6.3 0.0017 18.3 6.3 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 KPA44947.1 - 0.0019 18.2 10.4 0.0019 18.2 10.4 2.8 2 1 1 3 3 3 1 Late embryogenesis abundant protein ApoLp-III PF07464.11 KPA44947.1 - 0.14 12.3 7.1 0.17 12.0 7.1 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 KPA44947.1 - 0.87 10.2 11.0 0.63 10.7 5.7 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KPA44947.1 - 1.2 9.7 14.4 3.8e+02 1.7 14.4 2.6 1 1 0 1 1 1 0 YtxH-like protein ECH_1 PF00378.20 KPA44949.1 - 2.6e-41 141.6 0.0 6.4e-39 133.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA44949.1 - 1.5e-24 87.1 0.1 2e-21 76.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase UCH PF00443.29 KPA44951.1 - 8e-42 143.5 0.2 2.2e-41 142.1 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KPA44951.1 - 4.9e-08 32.8 5.5 0.03 14.2 1.9 3.8 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.6 KPA44951.1 - 5.5e-06 26.2 6.4 4.2e-05 23.3 6.4 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 KPA44951.1 - 0.0079 16.1 0.0 0.04 13.9 0.0 2.1 2 0 0 2 2 2 1 PUB domain Peptidase_C98 PF15499.6 KPA44951.1 - 0.073 12.5 0.2 2.1 7.8 0.1 2.8 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Kelch_1 PF01344.25 KPA44951.1 - 0.2 11.3 0.4 0.46 10.1 0.4 1.6 1 0 0 1 1 1 0 Kelch motif DUF3433 PF11915.8 KPA44952.1 - 2.9e-40 136.6 9.8 3.1e-25 88.4 0.6 4.2 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Glyco_hydro_61 PF03443.14 KPA44953.1 - 3.4e-08 33.7 0.2 7.4e-08 32.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 KPA44953.1 - 2.3e-05 25.1 0.0 2.3e-05 25.1 0.0 1.8 2 1 1 3 3 3 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading FAT PF02259.23 KPA44954.1 - 1e-74 251.8 4.8 2.2e-74 250.8 4.8 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KPA44954.1 - 9.3e-35 120.6 0.1 2.7e-34 119.1 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KPA44954.1 - 2.1e-06 27.5 0.2 4.9e-06 26.3 0.2 1.7 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 KPA44954.1 - 0.02 15.0 2.4 1.5 9.1 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KPA44954.1 - 0.32 11.3 3.5 0.31 11.4 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPA44954.1 - 1.3 8.9 5.7 10 6.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AMP-binding PF00501.28 KPA44955.1 - 3.3e-40 138.0 0.0 4.7e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KPA44955.1 - 9.6e-06 25.4 1.1 3.4e-05 23.7 0.3 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KPA44955.1 - 1.1e-05 26.3 0.3 3.2e-05 24.8 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1126 PF06565.12 KPA44955.1 - 0.075 12.9 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 DUF1126 PH-like domain DUF1757 PF08560.10 KPA44956.1 - 1.6e-06 28.3 0.0 2.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) TPR_2 PF07719.17 KPA44957.1 - 4.3e-28 95.1 19.1 0.00055 19.8 0.4 10.5 12 0 0 12 12 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA44957.1 - 6.4e-27 93.6 11.6 3e-23 81.8 0.2 5.4 4 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KPA44957.1 - 1e-26 91.6 9.7 0.00011 21.8 0.8 9.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 KPA44957.1 - 5.8e-23 81.2 15.2 0.00063 20.2 0.0 7.9 6 2 3 9 9 8 8 Tetratricopeptide repeat TPR_8 PF13181.6 KPA44957.1 - 6.3e-20 69.7 3.7 0.0026 17.8 0.2 9.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPA44957.1 - 7.5e-19 68.1 14.2 0.00015 22.3 0.0 9.2 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KPA44957.1 - 4.4e-17 61.3 11.6 0.022 15.5 0.0 9.8 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPA44957.1 - 1.4e-15 57.4 17.6 0.00021 21.5 0.1 9.2 7 2 3 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 KPA44957.1 - 3.5e-11 42.3 8.3 3.1 8.0 0.0 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 KPA44957.1 - 6.1e-10 38.6 5.7 0.19 11.7 0.2 7.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KPA44957.1 - 1.7e-09 37.2 5.9 0.018 14.7 0.0 7.1 8 1 1 9 9 9 3 TPR repeat TPR_6 PF13174.6 KPA44957.1 - 5.4e-08 33.0 6.9 0.74 10.6 0.1 8.4 7 2 2 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 KPA44957.1 - 1.2e-07 31.8 5.4 0.023 14.9 0.1 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KPA44957.1 - 0.00035 19.9 6.9 0.045 13.0 0.1 4.7 4 3 3 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 KPA44957.1 - 0.00077 19.8 0.4 2.1 9.2 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KPA44957.1 - 0.0013 18.2 1.1 3.3 7.0 0.0 3.9 3 1 0 4 4 4 1 Coatomer epsilon subunit TPR_21 PF09976.9 KPA44957.1 - 0.0017 18.1 7.5 4 7.1 0.1 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat-like domain TPR_5 PF12688.7 KPA44957.1 - 0.048 13.9 0.3 0.26 11.6 0.0 2.5 2 0 0 2 2 1 0 Tetratrico peptide repeat RPN7 PF10602.9 KPA44957.1 - 0.049 13.4 1.5 30 4.3 0.0 4.1 3 1 1 4 4 3 0 26S proteasome subunit RPN7 HrpB1_HrpK PF09613.10 KPA44957.1 - 0.055 13.1 0.0 3.2 7.4 0.1 2.9 3 0 0 3 3 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Rapsyn_N PF10579.9 KPA44957.1 - 0.14 12.2 0.1 36 4.6 0.0 3.6 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPR_20 PF14561.6 KPA44957.1 - 0.27 11.6 5.9 9.4 6.6 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 KPA44957.1 - 0.29 11.2 2.3 26 5.0 0.0 4.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain IGPD PF00475.18 KPA44958.1 - 1.1e-59 200.8 0.4 1.5e-59 200.4 0.4 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase ArgJ PF01960.18 KPA44959.1 - 2.5e-150 500.4 0.9 2.9e-150 500.2 0.9 1.0 1 0 0 1 1 1 1 ArgJ family IF-2B PF01008.17 KPA44960.1 - 2.2e-44 151.8 0.5 6.8e-44 150.2 0.5 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF562 PF04763.12 KPA44960.1 - 0.089 12.2 0.0 7.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF562) DUF3684 PF12449.8 KPA44961.1 - 0 1467.2 0.0 0 1466.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KPA44961.1 - 0.00011 22.1 0.0 0.00042 20.1 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reprolysin_5 PF13688.6 KPA44961.1 - 0.0048 17.1 0.2 0.015 15.5 0.2 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 WLM PF08325.10 KPA44961.1 - 0.087 12.9 1.0 0.19 11.8 0.1 2.0 2 0 0 2 2 2 0 WLM domain Arginosuc_synth PF00764.19 KPA44962.1 - 1.6e-135 452.3 0.0 1.9e-135 452.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KPA44962.1 - 0.03 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC MMtag PF10159.9 KPA44963.1 - 4.3e-31 107.0 3.5 1.1e-30 105.7 3.5 1.7 1 0 0 1 1 1 1 Multiple myeloma tumor-associated Med6 PF04934.14 KPA44964.1 - 9.1e-37 125.8 0.0 1.3e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component RR_TM4-6 PF06459.12 KPA44964.1 - 0.29 10.9 3.2 5.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 HA2 PF04408.23 KPA44965.1 - 4.7e-26 91.2 0.0 4.7e-26 91.2 0.0 3.2 4 0 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KPA44965.1 - 4.3e-12 46.4 0.1 5.5e-11 42.8 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KPA44965.1 - 2.6e-11 43.7 0.0 5.9e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KPA44965.1 - 8.2e-09 35.5 0.2 9.5e-08 32.0 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KPA44965.1 - 1.7e-05 25.1 0.1 0.00013 22.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPA44965.1 - 9.5e-05 22.2 0.0 0.00044 20.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KPA44965.1 - 0.00034 20.9 0.0 0.00085 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KPA44965.1 - 0.0057 15.8 0.1 0.02 14.0 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase PF06745.13 KPA44965.1 - 0.015 14.6 0.2 0.056 12.8 0.0 2.0 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 KPA44965.1 - 0.025 14.0 0.0 0.062 12.7 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.6 KPA44965.1 - 0.026 15.0 0.0 0.026 15.0 0.0 3.5 2 2 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KPA44965.1 - 0.077 12.3 0.1 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family SAP PF02037.27 KPA44965.1 - 0.37 10.6 2.0 1.1 9.0 2.0 1.8 1 0 0 1 1 1 0 SAP domain Metallophos PF00149.28 KPA44966.1 - 5e-37 128.4 0.1 9.3e-37 127.5 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short_C2 PF13561.6 KPA44967.1 - 4.9e-55 186.6 6.8 1.1e-54 185.5 6.8 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA44967.1 - 1.1e-34 119.6 6.2 7.6e-34 116.9 6.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA44967.1 - 1.5e-07 31.5 2.0 1.9e-07 31.1 0.3 1.8 2 0 0 2 2 2 1 KR domain SBDS_C PF09377.10 KPA44967.1 - 0.0012 18.8 0.2 0.002 18.1 0.2 1.6 1 1 0 1 1 1 1 SBDS protein C-terminal domain 3HCDH_N PF02737.18 KPA44967.1 - 0.015 15.1 1.7 0.016 15.1 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KPA44967.1 - 0.019 14.5 0.1 0.65 9.4 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KPA44967.1 - 0.019 14.3 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KPA44967.1 - 0.021 14.5 0.3 0.05 13.2 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HATPase_c PF02518.26 KPA44967.1 - 0.045 14.3 0.0 0.68 10.5 0.0 2.4 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NAD_Gly3P_dh_N PF01210.23 KPA44967.1 - 0.055 13.4 1.9 0.088 12.8 0.9 1.8 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3150 PF11348.8 KPA44967.1 - 0.17 11.1 0.1 1.8 7.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) TauD PF02668.16 KPA44968.1 - 5.2e-41 141.2 0.0 8.3e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KPA44968.1 - 5.9e-10 39.7 0.9 1.6e-09 38.3 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 KPA44968.1 - 0.098 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 CsiD AJAP1_PANP_C PF15298.6 KPA44969.1 - 0.78 9.9 4.0 2.3 8.4 0.0 2.5 3 0 0 3 3 3 0 AJAP1/PANP C-terminus UCH PF00443.29 KPA44970.1 - 5.7e-37 127.6 0.0 1.2e-36 126.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPA44970.1 - 3.7e-09 36.6 0.8 1.1e-08 35.0 0.8 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2387 PF09526.10 KPA44970.1 - 0.6 10.3 2.2 21 5.4 0.1 2.6 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) TPT PF03151.16 KPA44971.1 - 4.8e-28 98.3 21.7 7.2e-28 97.8 21.7 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KPA44971.1 - 0.0014 18.8 40.3 0.037 14.2 15.0 2.7 3 0 0 3 3 3 2 EamA-like transporter family COMPASS-Shg1 PF05205.12 KPA44972.1 - 1.8e-24 86.4 0.3 1.8e-24 86.4 0.3 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 Glyco_hydro_61 PF03443.14 KPA44973.1 - 3e-64 216.7 0.0 3.7e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Mito_carr PF00153.27 KPA44974.1 - 2.3e-19 69.1 0.7 1.8e-05 24.6 0.0 4.4 3 2 0 3 3 3 3 Mitochondrial carrier protein Fer2 PF00111.27 KPA44975.1 - 5.6e-14 51.9 0.7 1e-13 51.0 0.7 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.12 KPA44976.1 - 5.6e-39 133.5 13.4 5.6e-39 133.5 13.4 2.9 2 1 0 2 2 2 1 Rrp15p Ndc1_Nup PF09531.10 KPA44976.1 - 3.1 6.4 10.4 4.5 5.8 10.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PhoD PF09423.10 KPA44977.1 - 6.6e-44 150.4 0.2 1.3e-43 149.4 0.2 1.4 1 1 0 1 1 1 1 PhoD-like phosphatase EMP24_GP25L PF01105.24 KPA44978.1 - 4.1e-47 160.5 1.8 4.6e-47 160.3 1.8 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SKIP_SNW PF02731.15 KPA44979.1 - 3.3e-67 225.1 7.5 3.3e-67 225.1 7.5 2.6 2 0 0 2 2 2 1 SKIP/SNW domain fn3_3 PF14686.6 KPA44980.1 - 8.5e-29 99.2 0.9 2.3e-28 97.8 0.9 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 KPA44980.1 - 1.6e-25 89.9 0.7 2.4e-25 89.3 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.6 KPA44980.1 - 0.0046 17.2 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Y_Y_Y PF07495.13 KPA44980.1 - 0.013 15.4 0.3 0.071 13.1 0.3 2.3 1 0 0 1 1 1 0 Y_Y_Y domain DUF1772 PF08592.11 KPA44981.1 - 0.027 14.8 8.0 0.048 14.0 8.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Glyco_hydro_16 PF00722.21 KPA44982.1 - 1.1e-09 38.0 0.0 2.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Tim17 PF02466.19 KPA44983.1 - 2.7e-41 140.4 7.2 3.5e-41 140.0 7.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PGP_phosphatase PF09419.10 KPA44985.1 - 1.8e-63 213.2 0.0 2e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KPA44985.1 - 0.00078 19.5 0.0 0.0018 18.3 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like ORC2 PF04084.14 KPA44986.1 - 2.6e-120 401.3 0.0 3.3e-120 401.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF1206 PF06724.11 KPA44988.1 - 0.19 11.8 3.2 0.76 9.9 0.1 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Gly-zipper_Omp PF13488.6 KPA44988.1 - 0.59 10.2 5.6 0.21 11.6 0.2 2.2 2 0 0 2 2 2 0 Glycine zipper Beta-APP PF03494.13 KPA44988.1 - 2.4 8.1 4.0 4.6 7.2 4.0 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF1754 PF08555.10 KPA44989.1 - 2e-11 44.5 21.7 3.3e-11 43.8 21.7 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.10 KPA44989.1 - 0.0055 16.1 16.7 0.0062 16.0 16.7 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 KPA44989.1 - 2.4 7.9 12.9 2.8 7.7 12.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 KPA44989.1 - 2.6 6.7 11.5 2.9 6.6 11.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Rav1p_C PF12234.8 KPA44989.1 - 4.2 5.7 6.3 4.6 5.5 6.3 1.0 1 0 0 1 1 1 0 RAVE protein 1 C terminal AA_permease_2 PF13520.6 KPA44990.1 - 1.5e-62 211.9 41.2 1.9e-62 211.5 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA44990.1 - 1.1e-27 96.8 28.5 1.1e-27 96.8 28.5 2.1 2 0 0 2 2 2 1 Amino acid permease Transmemb_17 PF09799.9 KPA44990.1 - 3.2 8.4 11.7 4.8 7.8 1.7 3.2 2 0 0 2 2 2 0 Predicted membrane protein 2-Hacid_dh_C PF02826.19 KPA44991.1 - 2.8e-52 176.7 0.0 4.4e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPA44991.1 - 5.2e-16 58.5 0.0 6.9e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Ank_2 PF12796.7 KPA44992.1 - 2.2e-42 143.5 0.1 5.8e-09 36.4 0.0 8.8 5 4 3 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA44992.1 - 5.5e-37 125.7 0.4 1.5e-06 28.7 0.2 8.7 8 0 0 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA44992.1 - 4.7e-36 118.7 3.1 0.0013 19.1 0.0 11.9 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 KPA44992.1 - 1.2e-31 108.3 5.1 2e-05 24.7 0.2 10.6 9 2 3 12 12 12 7 Ankyrin repeats (many copies) Ank PF00023.30 KPA44992.1 - 3.9e-29 99.8 2.2 1.8e-05 25.0 0.2 11.7 11 2 1 12 12 12 6 Ankyrin repeat F-box-like PF12937.7 KPA44992.1 - 9.9e-10 38.2 0.0 3.3e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA44992.1 - 5.3e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KPA44992.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 F-box F-box_5 PF18511.1 KPA44992.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box OTT_1508_deam PF14441.6 KPA44993.1 - 2.5e-18 65.8 1.2 4.7e-18 65.0 1.2 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase UvrB PF12344.8 KPA44997.1 - 2 8.3 5.5 0.68 9.8 0.3 2.6 2 1 0 2 2 2 0 Ultra-violet resistance protein B Peptidase_M18 PF02127.15 KPA44998.1 - 1.4e-128 429.4 0.0 1.6e-128 429.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Phage_Gp17 PF17549.2 KPA44999.1 - 0.095 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Gene Product 17 CAF1A PF12253.8 KPA45003.1 - 3.7e-24 84.7 4.3 3.7e-24 84.7 4.3 3.3 4 0 0 4 4 4 1 Chromatin assembly factor 1 subunit A Mitofilin PF09731.9 KPA45003.1 - 0.43 9.4 31.9 0.77 8.5 31.9 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Presenilin PF01080.17 KPA45003.1 - 4.1 6.1 16.2 8.2 5.1 16.2 1.6 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 KPA45003.1 - 9.4 4.9 20.0 1.6 7.4 14.4 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein EXS PF03124.14 KPA45005.1 - 7.1e-101 337.8 33.2 8.7e-101 337.5 33.2 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KPA45005.1 - 3.7e-85 287.2 2.8 3.7e-85 287.2 2.8 1.8 2 0 0 2 2 2 1 SPX domain zf-RING-like PF08746.11 KPA45006.1 - 0.0065 16.8 1.6 0.0065 16.8 1.6 2.4 2 2 1 3 3 3 1 RING-like domain PHD PF00628.29 KPA45006.1 - 0.07 13.0 4.4 0.18 11.7 4.4 1.7 1 1 0 1 1 1 0 PHD-finger zf-HIT PF04438.16 KPA45006.1 - 0.9 9.5 6.5 1.6 8.7 0.3 2.5 3 0 0 3 3 3 0 HIT zinc finger ABC_tran PF00005.27 KPA45007.1 - 2e-50 170.8 0.0 1e-31 110.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KPA45007.1 - 4.1e-44 151.3 25.4 1.5e-27 96.9 10.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KPA45007.1 - 2.9e-14 53.6 0.1 0.003 17.4 0.0 4.5 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPA45007.1 - 5.6e-13 48.8 6.4 0.00011 21.7 0.1 4.6 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPA45007.1 - 8.2e-08 31.9 0.9 0.0024 17.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KPA45007.1 - 1.4e-05 25.5 0.0 0.12 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KPA45007.1 - 1.7e-05 24.8 4.8 0.019 14.9 0.2 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 KPA45007.1 - 1.9e-05 24.9 0.0 0.23 11.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KPA45007.1 - 3e-05 24.1 0.0 0.51 10.4 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 KPA45007.1 - 5.6e-05 23.0 0.3 0.44 10.2 0.0 3.0 4 0 0 4 4 3 2 AAA ATPase domain AAA_23 PF13476.6 KPA45007.1 - 0.0001 22.9 0.8 0.11 13.0 0.0 2.6 3 0 0 3 3 2 2 AAA domain Dynamin_N PF00350.23 KPA45007.1 - 0.0001 22.4 1.5 0.055 13.5 0.1 2.5 2 0 0 2 2 2 2 Dynamin family DUF815 PF05673.13 KPA45007.1 - 0.00014 21.2 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_33 PF13671.6 KPA45007.1 - 0.00018 21.7 0.0 1.2 9.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 KPA45007.1 - 0.0014 19.1 0.1 0.23 11.9 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KPA45007.1 - 0.0015 19.1 0.0 0.42 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KPA45007.1 - 0.0023 17.6 0.2 0.087 12.4 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KPA45007.1 - 0.0025 17.1 0.0 0.12 11.6 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 KPA45007.1 - 0.003 17.3 0.2 0.25 11.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KPA45007.1 - 0.0045 16.5 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KPA45007.1 - 0.0049 16.7 0.1 0.71 9.6 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 KPA45007.1 - 0.0086 15.5 0.4 0.22 10.8 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Roc PF08477.13 KPA45007.1 - 0.011 16.0 0.1 3.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KPA45007.1 - 0.015 15.7 0.1 7.7 7.0 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_PrkA PF08298.11 KPA45007.1 - 0.021 13.7 0.3 2.1 7.1 0.2 2.8 3 0 0 3 3 3 0 PrkA AAA domain NACHT PF05729.12 KPA45007.1 - 0.042 13.8 2.0 5.1 7.0 0.0 2.9 3 0 0 3 3 3 0 NACHT domain RAMP4 PF06624.12 KPA45007.1 - 0.055 13.5 0.2 0.19 11.8 0.2 1.9 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 TsaE PF02367.17 KPA45007.1 - 0.069 13.2 0.1 7.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KPA45007.1 - 0.13 12.2 0.5 8.1 6.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 KPA45007.1 - 0.18 11.0 0.0 9.4 5.4 0.0 2.4 2 0 0 2 2 2 0 Septin DUF87 PF01935.17 KPA45007.1 - 0.68 10.0 3.7 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain MFS_1 PF07690.16 KPA45008.1 - 1.9e-34 119.2 39.0 1.7e-29 102.9 25.0 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily AzlC PF03591.14 KPA45008.1 - 0.01 16.3 1.5 0.01 16.3 1.5 2.8 2 1 1 3 3 3 0 AzlC protein OATP PF03137.20 KPA45008.1 - 0.099 10.9 9.4 0.055 11.7 1.6 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1043 PF06295.12 KPA45008.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Sulfatase PF00884.23 KPA45009.1 - 3.6e-59 200.7 0.2 5.2e-59 200.2 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPA45009.1 - 0.00092 18.9 0.6 0.18 11.4 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KPA45009.1 - 0.03 14.6 0.1 0.067 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) FHA PF00498.26 KPA45010.1 - 2.8e-05 24.4 0.0 5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KPA45010.1 - 0.00049 20.4 0.0 0.00082 19.7 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF3732 PF12532.8 KPA45010.1 - 0.23 11.0 0.1 0.33 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) HbrB PF08539.11 KPA45012.1 - 7.6e-54 182.2 0.0 2e-53 180.9 0.0 1.8 1 0 0 1 1 1 1 HbrB-like Gon7 PF08738.10 KPA45013.1 - 2.3e-10 40.5 5.2 1.1e-09 38.3 1.8 2.0 1 1 1 2 2 2 2 Gon7 family DUF4476 PF14771.6 KPA45013.1 - 0.014 15.6 0.0 0.018 15.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Arfaptin PF06456.13 KPA45013.1 - 0.03 13.9 0.5 0.036 13.6 0.5 1.1 1 0 0 1 1 1 0 Arfaptin-like domain DUF4611 PF15387.6 KPA45013.1 - 0.048 13.9 1.5 0.062 13.5 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Vps39_1 PF10366.9 KPA45014.1 - 6e-34 116.6 0.0 1.1e-32 112.5 0.0 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KPA45014.1 - 1.6e-27 96.1 0.0 8.4e-27 93.8 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KPA45014.1 - 8.3e-12 45.3 0.0 2.1e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KPA45014.1 - 0.00032 20.6 8.5 0.0011 18.8 2.8 3.5 3 1 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.28 KPA45014.1 - 0.014 15.1 8.2 0.78 9.7 0.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA45014.1 - 0.02 15.1 0.8 5.6 7.3 0.0 3.8 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KPA45014.1 - 0.025 14.7 1.0 73 3.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KPA45014.1 - 0.05 14.1 1.1 14 6.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KPA45014.1 - 0.15 12.0 0.1 0.4 10.7 0.1 1.7 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 PPR_2 PF13041.6 KPA45014.1 - 0.48 10.7 1.6 7.4 6.9 0.2 3.2 4 0 0 4 4 4 0 PPR repeat family TPR_12 PF13424.6 KPA45014.1 - 0.53 10.6 1.7 26 5.2 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KPA45014.1 - 9.9 6.7 6.7 14 6.2 0.7 4.1 4 1 1 5 5 4 0 Tetratricopeptide repeat SPX PF03105.19 KPA45015.1 - 1.7e-42 146.8 2.3 4.2e-29 102.7 0.9 2.3 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 KPA45015.1 - 5.9e-35 121.2 37.8 8e-35 120.8 37.8 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KPA45015.1 - 7e-26 91.1 36.7 7e-26 91.1 36.7 2.0 2 1 1 3 3 3 2 Citrate transporter ABC_membrane PF00664.23 KPA45016.1 - 1.6e-84 283.8 29.8 5.4e-45 154.2 10.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA45016.1 - 3.5e-66 221.9 0.0 1.2e-32 113.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPA45016.1 - 4.3e-14 52.5 2.1 0.00013 21.5 0.0 4.3 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KPA45016.1 - 1.4e-06 28.8 1.4 0.095 13.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KPA45016.1 - 7.3e-06 25.6 2.1 0.053 13.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KPA45016.1 - 7.5e-05 22.5 5.4 0.0034 17.1 0.3 3.6 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KPA45016.1 - 8.3e-05 21.9 0.3 0.13 11.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 KPA45016.1 - 0.00018 21.5 0.2 0.37 10.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KPA45016.1 - 0.00023 21.3 0.6 0.023 14.8 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain APS_kinase PF01583.20 KPA45016.1 - 0.0004 20.3 0.4 0.17 11.8 0.2 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_21 PF13304.6 KPA45016.1 - 0.00052 19.9 4.1 1.5 8.6 0.0 4.4 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KPA45016.1 - 0.00069 20.0 0.3 0.56 10.6 0.0 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KPA45016.1 - 0.00078 19.6 0.1 1 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KPA45016.1 - 0.00097 19.7 0.1 0.95 10.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KPA45016.1 - 0.0012 19.1 3.0 1.7 8.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 KPA45016.1 - 0.0021 17.7 0.6 5.6 6.5 0.0 3.6 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.6 KPA45016.1 - 0.0037 17.5 0.5 6.3 7.1 0.2 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 KPA45016.1 - 0.0095 14.8 0.0 0.032 13.0 0.0 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class ATP_bind_1 PF03029.17 KPA45016.1 - 0.012 15.4 0.2 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 KPA45016.1 - 0.013 15.5 0.3 8.4 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 KPA45016.1 - 0.021 13.8 0.5 0.19 10.7 0.1 2.4 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KPA45016.1 - 0.037 13.6 0.4 3.1 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3987 PF13148.6 KPA45016.1 - 0.043 12.8 0.6 1.9 7.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) NB-ARC PF00931.22 KPA45016.1 - 0.053 12.7 0.3 1.4 8.0 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 KPA45016.1 - 0.079 13.0 0.2 4.3 7.5 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KPA45016.1 - 0.1 13.1 3.2 2.1 8.8 0.1 3.0 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 KPA45016.1 - 0.12 12.1 0.3 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DEAD PF00270.29 KPA45016.1 - 0.16 11.7 0.7 0.88 9.3 0.0 2.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_17 PF13207.6 KPA45016.1 - 1.3 9.5 3.5 27 5.2 0.1 3.1 3 0 0 3 3 2 0 AAA domain Pyr_redox_2 PF07992.14 KPA45017.1 - 3e-30 105.5 0.0 4.5e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA45017.1 - 3.3e-13 50.0 2.8 1.6e-12 47.8 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA45017.1 - 8.4e-06 25.2 0.1 1.6e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA45017.1 - 9.5e-06 25.0 0.2 1.9e-05 24.0 0.2 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KPA45017.1 - 0.00081 18.5 0.3 0.0016 17.6 0.2 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KPA45017.1 - 0.0027 17.0 3.3 0.13 11.5 0.1 2.9 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 KPA45017.1 - 0.0078 15.3 0.2 3.4 6.6 0.0 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KPA45017.1 - 0.028 14.4 0.6 18 5.3 0.0 3.4 2 1 1 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KPA45017.1 - 0.03 13.0 1.9 1.2 7.8 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 KPA45017.1 - 0.034 13.7 0.4 0.93 9.0 0.1 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KPA45017.1 - 0.034 13.4 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KPA45017.1 - 0.039 12.8 0.1 0.45 9.3 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DNA_processg_A PF02481.15 KPA45017.1 - 0.048 12.9 0.5 3.9 6.7 0.4 2.2 1 1 1 2 2 2 0 DNA recombination-mediator protein A Cpn60_TCP1 PF00118.24 KPA45017.1 - 0.062 11.9 0.1 0.094 11.3 0.1 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family FAD_oxidored PF12831.7 KPA45017.1 - 9.1 5.5 7.1 3 7.1 0.1 2.7 2 1 0 3 3 3 0 FAD dependent oxidoreductase Acetyltransf_8 PF13523.6 KPA45018.1 - 2.1e-40 137.7 0.9 3.5e-40 137.0 0.9 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 KPA45019.1 - 7.7e-98 327.9 0.0 9.1e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA45019.1 - 2.2e-13 51.0 0.0 5.2e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 KPA45019.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF4050 PF13259.6 KPA45020.1 - 5.3e-59 199.6 0.8 1.1e-58 198.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) PAPA-1 PF04795.12 KPA45022.1 - 7.9e-28 97.1 4.5 7.9e-28 97.1 4.5 3.5 4 1 0 4 4 4 1 PAPA-1-like conserved region Pex14_N PF04695.13 KPA45023.1 - 2.2e-39 135.6 2.2 2.2e-39 135.6 2.2 3.0 2 2 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2730 PF10805.8 KPA45023.1 - 0.033 14.3 0.5 10 6.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) SOG2 PF10428.9 KPA45023.1 - 0.042 13.1 12.3 0.019 14.2 10.3 1.4 1 1 0 1 1 1 0 RAM signalling pathway protein DUF4366 PF14283.6 KPA45023.1 - 0.054 13.5 0.0 0.054 13.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Chromo PF00385.24 KPA45024.1 - 2.9e-08 33.5 2.7 1.1e-07 31.7 2.9 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain VitK2_biosynth PF02621.14 KPA45024.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Menaquinone biosynthesis Ras PF00071.22 KPA45025.1 - 3.9e-63 211.9 0.2 4.7e-63 211.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA45025.1 - 2.7e-35 121.2 0.2 3.9e-35 120.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA45025.1 - 4.2e-13 49.1 0.1 5.5e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KPA45025.1 - 7.8e-08 32.4 0.1 1.2e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPA45025.1 - 0.00029 20.4 0.1 0.0012 18.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KPA45025.1 - 0.00041 19.8 0.1 0.0006 19.2 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KPA45025.1 - 0.00048 20.1 0.8 0.018 14.9 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KPA45025.1 - 0.0028 17.9 0.1 0.015 15.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KPA45025.1 - 0.014 14.8 0.0 0.028 13.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KPA45025.1 - 0.016 15.3 0.1 0.044 13.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KPA45025.1 - 0.017 15.5 0.1 0.028 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KPA45025.1 - 0.022 15.3 0.1 0.037 14.5 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KPA45025.1 - 0.029 14.1 0.1 0.064 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KPA45025.1 - 0.032 13.6 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 KPA45025.1 - 0.088 12.3 0.1 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region SpoIIID PF12116.8 KPA45025.1 - 0.099 12.7 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_21 PF13304.6 KPA45025.1 - 0.099 12.4 0.6 0.14 11.9 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 KPA45025.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Brix PF04427.18 KPA45026.1 - 1.3e-39 136.4 0.0 1.6e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain F-box-like PF12937.7 KPA45027.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 F-box-like Arb2 PF09757.9 KPA45028.1 - 2.1e-101 338.4 0.3 2.9e-101 338.0 0.3 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KPA45028.1 - 2.9e-80 270.0 0.0 4.4e-80 269.4 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Synaphin PF05835.12 KPA45028.1 - 0.23 11.7 7.2 2 8.7 0.1 2.4 2 0 0 2 2 2 0 Synaphin protein LRR_4 PF12799.7 KPA45029.1 - 0.59 10.6 10.7 1.5 9.3 0.9 4.6 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) VEFS-Box PF09733.9 KPA45030.1 - 1.6e-08 34.5 0.5 3.4e-08 33.4 0.5 1.5 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.29 KPA45030.1 - 0.0012 18.7 4.5 0.0012 18.7 4.5 2.4 2 0 0 2 2 2 1 PHD-finger Coatomer_b_Cpla PF14806.6 KPA45030.1 - 0.17 11.9 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Fer4_2 PF12797.7 KPA45030.1 - 2.6 8.3 5.8 1.8 8.8 2.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain DUF382 PF04037.13 KPA45031.1 - 3.3e-59 198.6 0.8 3.3e-59 198.6 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 KPA45031.1 - 4.9e-18 64.7 3.5 1.1e-17 63.6 3.5 1.6 1 0 0 1 1 1 1 PSP COX4 PF02936.14 KPA45031.1 - 0.34 10.9 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV TPT PF03151.16 KPA45032.1 - 2.3e-57 194.5 11.3 2.8e-57 194.3 11.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KPA45032.1 - 9.2e-11 42.1 25.4 1.8e-06 28.2 9.1 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KPA45032.1 - 1.4e-06 27.8 13.4 7.5e-06 25.4 13.4 2.0 1 1 0 1 1 1 1 UAA transporter family SLATT_5 PF18160.1 KPA45032.1 - 0.15 11.3 0.1 0.34 10.2 0.1 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Mus7 PF09462.10 KPA45033.1 - 1.5e-129 433.7 4.3 1.5e-129 433.7 4.3 1.6 2 0 0 2 2 2 1 Mus7/MMS22 family ORC5_C PF14630.6 KPA45033.1 - 1.8e-84 283.6 0.0 7e-84 281.7 0.0 2.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KPA45033.1 - 1.1e-11 45.4 0.0 4.7e-11 43.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KPA45033.1 - 0.017 14.5 0.2 0.077 12.3 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KPA45033.1 - 0.029 14.6 0.1 0.18 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KPA45033.1 - 0.062 12.7 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein MFS_1 PF07690.16 KPA45034.1 - 1.3e-46 159.1 37.1 1.3e-46 159.1 37.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA45034.1 - 2.4e-16 59.7 10.0 2.4e-16 59.7 10.0 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KPA45034.1 - 2e-07 30.7 5.1 2e-07 30.7 5.1 2.0 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF2583 PF10762.9 KPA45034.1 - 0.031 14.7 2.4 0.031 14.7 2.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) DUF3040 PF11239.8 KPA45034.1 - 0.1 12.9 0.1 0.1 12.9 0.1 4.2 5 1 0 5 5 5 0 Protein of unknown function (DUF3040) Zn_clus PF00172.18 KPA45035.1 - 1.3e-08 34.8 7.9 2.3e-08 34.0 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA45035.1 - 2.3e-06 26.8 0.0 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain COX4 PF02936.14 KPA45036.1 - 1.6e-44 151.3 0.1 1.8e-44 151.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.11 KPA45036.1 - 0.041 14.2 0.1 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) AAA_2 PF07724.14 KPA45037.1 - 7.4e-33 114.1 0.0 1.6e-32 113.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KPA45037.1 - 1.7e-11 44.6 0.0 2.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KPA45037.1 - 3.2e-09 36.7 0.0 7.4e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KPA45037.1 - 4.2e-07 30.1 0.0 9.6e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 KPA45037.1 - 0.0009 18.4 0.0 0.0021 17.2 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 KPA45037.1 - 0.0029 17.9 0.1 0.021 15.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPA45037.1 - 0.0043 17.5 0.2 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KPA45037.1 - 0.007 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 KPA45037.1 - 0.0075 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KPA45037.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KPA45037.1 - 0.058 14.0 0.7 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KPA45037.1 - 0.1 12.0 0.0 0.78 9.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein T2SSE PF00437.20 KPA45037.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 KPA45037.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KPA45037.1 - 0.14 11.9 0.0 0.42 10.3 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KPA45037.1 - 0.17 12.4 0.0 0.41 11.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Alpha-amylase_C PF02806.18 KPA45038.1 - 5.3e-28 97.3 0.1 1.6e-27 95.8 0.1 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KPA45038.1 - 7.6e-18 64.7 0.4 5e-17 62.0 0.0 2.4 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KPA45038.1 - 7.3e-16 58.6 1.2 2.2e-12 47.2 1.2 2.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KPA45038.1 - 0.1 11.7 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain ATP-synt_ab PF00006.25 KPA45040.1 - 1.1e-61 208.2 0.0 1.6e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KPA45040.1 - 1.3e-23 83.3 0.4 3.5e-23 81.9 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 KPA45040.1 - 0.0096 15.8 0.3 0.025 14.5 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 KPA45040.1 - 0.015 14.5 0.4 0.081 12.1 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 KPA45040.1 - 0.015 15.7 0.1 0.75 10.2 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KPA45040.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KPA45040.1 - 0.029 13.7 0.1 0.051 12.9 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KPA45040.1 - 0.039 14.3 0.9 0.48 10.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KPA45040.1 - 0.051 13.5 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain T3SS_ATPase_C PF18269.1 KPA45040.1 - 0.052 13.4 0.7 0.32 10.9 0.7 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RNA_helicase PF00910.22 KPA45040.1 - 0.08 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KPA45040.1 - 0.17 11.9 0.1 0.42 10.6 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KPA45040.1 - 0.19 12.1 0.5 0.51 10.7 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain Zn_clus PF00172.18 KPA45041.1 - 6.4e-08 32.6 10.4 1e-07 32.0 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA45041.1 - 0.019 13.8 0.1 0.034 13.0 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain P5-ATPase PF12409.8 KPA45041.1 - 0.17 12.0 0.3 0.4 10.8 0.3 1.6 1 0 0 1 1 1 0 P5-type ATPase cation transporter AAA PF00004.29 KPA45042.1 - 8.6e-38 129.7 0.0 1.4e-36 125.8 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA45042.1 - 3.7e-10 39.4 0.0 1e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KPA45042.1 - 1e-05 25.3 0.0 3.2e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPA45042.1 - 3.1e-05 24.4 0.1 0.0014 19.0 0.1 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPA45042.1 - 0.00051 20.3 0.2 0.1 12.9 0.1 3.1 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KPA45042.1 - 0.0011 19.0 0.0 0.0041 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KPA45042.1 - 0.0081 16.2 0.1 0.027 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KPA45042.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KPA45042.1 - 0.013 15.3 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KPA45042.1 - 0.014 15.3 0.6 15 5.4 0.0 3.6 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 KPA45042.1 - 0.022 14.0 0.0 0.047 12.9 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 KPA45042.1 - 0.032 14.8 0.1 0.11 13.0 0.1 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KPA45042.1 - 0.033 13.6 0.2 0.12 11.7 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KPA45042.1 - 0.047 14.1 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KPA45042.1 - 0.056 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KPA45042.1 - 0.1 12.0 0.0 2.4 7.5 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein Apolipoprotein PF01442.18 KPA45043.1 - 0.07 13.0 12.9 0.12 12.2 12.9 1.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KPA45043.1 - 0.39 10.8 17.9 0.045 13.8 7.4 2.8 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Codanin-1_C PF15296.6 KPA45043.1 - 2.2 8.4 9.0 0.61 10.2 3.0 2.5 2 1 1 3 3 3 0 Codanin-1 C-terminus YtxH PF12732.7 KPA45043.1 - 6 7.5 13.1 0.33 11.5 3.1 2.5 1 1 1 2 2 2 0 YtxH-like protein BSD PF03909.17 KPA45044.1 - 1.6e-27 95.2 1.5 1.8e-13 50.3 0.1 2.7 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 KPA45044.1 - 8.3e-26 90.1 0.1 3e-25 88.3 0.0 2.0 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain DHC_N1 PF08385.12 KPA45044.1 - 0.0055 15.4 0.1 0.21 10.2 0.0 2.3 2 1 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 Transket_pyr PF02779.24 KPA45045.1 - 3.1e-61 206.1 0.0 5e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KPA45045.1 - 4.9e-57 193.2 0.0 7.4e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KPA45045.1 - 8.8e-55 184.6 0.0 1.5e-54 183.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KPA45045.1 - 9.3e-20 70.0 0.4 1.9e-19 68.9 0.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus WD40 PF00400.32 KPA45046.1 - 1.2e-23 82.9 18.6 3.6e-08 33.9 0.2 7.2 6 2 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA45046.1 - 1.1e-06 28.8 1.0 8.6 6.7 0.0 5.1 4 2 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA45046.1 - 0.0045 16.0 1.3 0.18 10.7 0.2 3.5 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 KPA45046.1 - 0.042 12.9 1.6 3.9 6.4 0.2 2.1 2 0 0 2 2 2 0 Coatomer WD associated region DUF2330 PF10092.9 KPA45046.1 - 0.17 11.0 0.1 0.4 9.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2330) MFS_1 PF07690.16 KPA45047.1 - 1.1e-31 110.0 47.3 1.1e-17 64.0 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 KPA45048.1 - 0.00024 20.9 5.3 0.079 12.8 0.2 2.2 2 0 0 2 2 2 2 Glycine zipper 2TM domain DUF4235 PF14019.6 KPA45048.1 - 0.05 13.7 0.1 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4235) DUF2076 PF09849.9 KPA45048.1 - 4.7 7.2 10.4 1.1e+02 2.7 10.4 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FAD_binding_3 PF01494.19 KPA45050.1 - 1.5e-76 257.9 0.0 2e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KPA45050.1 - 8.8e-38 129.9 0.1 1.5e-37 129.2 0.1 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.27 KPA45050.1 - 0.0024 18.4 0.0 0.012 16.1 0.0 2.3 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA45050.1 - 0.0062 15.8 0.0 0.021 14.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA45050.1 - 0.021 14.4 0.0 0.64 9.5 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KPA45050.1 - 0.025 14.2 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 KPA45050.1 - 0.027 14.7 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPA45050.1 - 0.072 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein XdhC_C PF13478.6 KPA45050.1 - 0.075 13.5 0.0 0.27 11.8 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 KPA45050.1 - 0.076 12.1 0.0 0.7 8.9 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 KPA45050.1 - 0.089 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family RGS PF00615.19 KPA45051.1 - 2.7e-06 27.7 0.0 4.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C48 PF02902.19 KPA45052.1 - 3.1e-18 66.4 0.1 5.3e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain YqfD PF06898.11 KPA45052.1 - 0.0049 15.8 0.2 0.0084 15.0 0.2 1.2 1 0 0 1 1 1 1 Putative stage IV sporulation protein YqfD MHYT PF03707.16 KPA45053.1 - 8.7e-24 83.5 19.6 5.9e-10 39.2 1.0 4.6 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat Cupin_8 PF13621.6 KPA45054.1 - 1.6e-37 129.6 0.0 2.6e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 KPA45054.1 - 3.8e-18 66.1 0.0 6.3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 KPA45054.1 - 6.1e-10 38.9 2.9 1.7e-08 34.3 0.0 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KPA45054.1 - 4.2e-05 23.7 1.2 0.16 12.3 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 KPA45054.1 - 0.0018 18.5 0.1 2.9 8.3 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Cupin_4 PF08007.12 KPA45054.1 - 0.007 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_2 PF07646.15 KPA45054.1 - 0.15 12.1 2.7 0.41 10.7 0.0 2.9 3 0 0 3 3 3 0 Kelch motif ANAPC4_WD40 PF12894.7 KPA45055.1 - 7e-05 23.1 0.0 0.21 11.9 0.0 4.1 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPA45055.1 - 0.0031 18.3 2.7 0.66 11.0 0.0 4.2 5 1 0 5 5 5 1 WD domain, G-beta repeat Hira PF07569.11 KPA45055.1 - 0.094 12.4 0.0 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 TUP1-like enhancer of split DSPc PF00782.20 KPA45056.1 - 1.6e-25 89.4 0.0 2e-20 73.0 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KPA45056.1 - 0.0014 18.2 0.0 0.0051 16.4 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KPA45056.1 - 0.13 12.4 0.1 0.78 9.8 0.1 2.2 3 0 0 3 3 3 0 Inositol hexakisphosphate DEAD_2 PF06733.15 KPA45057.1 - 1.7e-56 190.6 0.6 3.8e-56 189.5 0.6 1.7 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KPA45057.1 - 7.7e-47 159.4 1.5 9.4e-44 149.4 0.4 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KPA45057.1 - 1.1e-43 149.3 0.0 4e-43 147.5 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KPA45057.1 - 5.4e-05 23.3 0.1 0.0024 17.9 0.1 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KPA45057.1 - 0.0006 18.6 0.0 0.0034 16.1 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KPA45057.1 - 0.0015 18.3 0.0 0.34 10.7 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase UvrD_C PF13361.6 KPA45057.1 - 0.068 12.5 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PhoH PF02562.16 KPA45057.1 - 0.076 12.5 0.1 3.7 6.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Troponin PF00992.20 KPA45057.1 - 5.7 7.3 8.5 4.2 7.7 1.7 2.4 2 0 0 2 2 2 0 Troponin DDHD PF02862.17 KPA45058.1 - 6.1e-21 75.6 2.5 4.8e-11 43.3 0.0 3.7 3 2 0 4 4 4 2 DDHD domain Abhydrolase_1 PF00561.20 KPA45058.1 - 0.073 12.7 0.0 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KPA45058.1 - 0.087 12.4 0.1 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase PHD20L1_u1 PF16660.5 KPA45058.1 - 5.8 7.7 7.9 46 4.9 0.2 3.5 3 0 0 3 3 3 0 PHD finger protein 20-like protein 1 zf-C2H2 PF00096.26 KPA45059.1 - 5e-13 48.7 22.2 0.0001 22.5 1.4 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA45059.1 - 8.8e-10 38.6 17.2 0.00071 20.2 0.4 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPA45059.1 - 0.0045 17.4 24.1 0.0046 17.3 2.0 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2HC_2 PF13913.6 KPA45059.1 - 0.038 13.9 0.6 0.12 12.3 0.6 1.9 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KPA45059.1 - 0.047 13.5 3.1 0.088 12.6 0.2 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KPA45059.1 - 0.067 13.5 7.9 0.23 11.8 6.6 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KPA45059.1 - 0.084 12.9 0.2 0.084 12.9 0.2 2.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KPA45059.1 - 0.088 13.0 5.2 0.21 11.7 0.5 2.4 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 KPA45059.1 - 1.5 9.2 7.7 11 6.4 0.1 3.4 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KPA45059.1 - 1.8 8.7 11.5 0.43 10.6 5.9 2.4 2 0 0 2 2 2 0 BED zinc finger PRP3 PF08572.10 KPA45060.1 - 6.4e-74 248.5 0.6 1e-73 247.8 0.6 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KPA45060.1 - 8.6e-48 162.2 0.3 8.6e-48 162.2 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) GET2 PF08690.10 KPA45060.1 - 7.2 6.2 9.3 0.36 10.4 3.2 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 RNA_pol_Rpb1_5 PF04998.17 KPA45061.1 - 3.3e-90 302.2 0.3 7.3e-90 301.0 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KPA45061.1 - 3.7e-68 228.9 0.4 1e-67 227.5 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KPA45061.1 - 4e-40 138.1 4.1 8.6e-39 133.7 2.9 3.2 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KPA45061.1 - 4e-32 111.3 0.0 1.7e-31 109.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KPA45061.1 - 2.6e-17 62.7 0.0 1.5e-16 60.3 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Histone PF00125.24 KPA45062.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KPA45062.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KPA45062.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KPA45062.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KPA45062.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KPA45062.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KPA45062.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KPA45063.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KPA45063.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KPA45063.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KPA45063.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KPA45063.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KPA45063.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KPA45063.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KPA45063.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KPA45063.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region zf-C2H2 PF00096.26 KPA45064.1 - 3.3e-10 39.9 13.5 0.0067 16.8 1.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA45064.1 - 1.5e-05 25.5 9.7 1 10.4 1.1 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger SHE3 PF17078.5 KPA45064.1 - 0.039 13.7 0.5 0.039 13.7 0.5 1.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 zf-Di19 PF05605.12 KPA45064.1 - 0.61 10.4 5.8 2.8 8.3 1.2 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding EPSP_synthase PF00275.20 KPA45065.1 - 7.2e-132 440.0 0.0 2.4e-131 438.3 0.0 1.8 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KPA45065.1 - 4.5e-101 337.4 0.0 8.5e-101 336.5 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KPA45065.1 - 1.9e-62 211.5 0.0 3.5e-62 210.7 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KPA45065.1 - 3.3e-36 124.8 0.0 1.1e-34 119.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KPA45065.1 - 3.3e-25 88.1 0.0 8.8e-25 86.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KPA45065.1 - 2.2e-07 30.9 0.0 4.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KPA45065.1 - 1.1e-06 28.2 0.0 2.9e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KPA45065.1 - 5.7e-06 26.4 0.0 0.00013 22.1 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 KPA45065.1 - 0.11 12.7 0.0 0.37 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 KPA45066.1 - 7.6e-27 92.9 2.0 2e-12 46.7 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPA45066.1 - 2.6e-07 30.3 0.0 6.1e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAM33 PF02330.16 KPA45066.1 - 0.0024 17.8 2.1 0.0033 17.4 2.1 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein Roughex PF06020.11 KPA45066.1 - 0.052 12.7 2.3 0.075 12.1 2.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 KPA45066.1 - 0.15 10.8 0.5 0.14 10.9 0.5 1.1 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.12 KPA45066.1 - 0.27 10.6 6.3 0.38 10.1 6.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger ATP-synt_D PF01813.17 KPA45067.1 - 4.2e-65 219.3 1.3 5.5e-65 218.9 1.3 1.2 1 0 0 1 1 1 1 ATP synthase subunit D PHM7_cyt PF14703.6 KPA45067.1 - 0.005 17.1 5.3 0.01 16.1 1.7 2.2 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter HtrL_YibB PF09612.10 KPA45067.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) APG6_N PF17675.1 KPA45067.1 - 0.14 12.7 4.1 0.071 13.6 1.0 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF5446 PF17522.2 KPA45067.1 - 0.15 12.2 2.4 0.15 12.2 0.7 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Prefoldin PF02996.17 KPA45067.1 - 0.74 9.7 7.9 1.2 9.1 0.1 3.1 3 1 0 3 3 3 0 Prefoldin subunit Suf PF05843.14 KPA45068.1 - 3.5e-13 50.2 8.6 0.014 15.4 0.3 6.6 3 2 3 6 6 6 4 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 KPA45068.1 - 8.6e-10 38.7 8.5 0.27 11.2 0.1 7.2 7 0 0 7 7 7 3 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 KPA45068.1 - 2.1e-09 37.4 22.6 3.1 8.9 0.6 11.3 9 4 4 13 13 13 3 Tetratricopeptide repeat TPR_15 PF13429.6 KPA45068.1 - 9e-07 28.4 7.4 3.3e-05 23.2 1.5 4.0 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPA45068.1 - 1.7e-06 27.7 2.2 0.19 12.0 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPA45068.1 - 4.3e-05 23.7 6.2 3.8 7.9 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.9 KPA45068.1 - 0.00031 20.5 1.9 0.0039 16.9 0.4 3.1 3 1 0 3 3 3 1 26S proteasome subunit RPN7 SNAP PF14938.6 KPA45068.1 - 0.0019 17.7 3.8 6 6.2 0.0 4.6 3 2 1 4 4 4 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KPA45068.1 - 0.0027 17.7 14.7 6.3 7.2 0.0 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KPA45068.1 - 0.039 13.1 12.3 0.027 13.6 0.6 5.4 2 2 3 6 6 6 0 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 KPA45068.1 - 0.064 13.7 0.3 41 4.9 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KPA45068.1 - 0.072 13.0 9.0 1.3e+02 2.7 0.4 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPA45068.1 - 0.087 13.5 0.0 8 7.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KPA45068.1 - 0.29 11.2 1.2 1.3 9.2 0.2 2.8 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain Clathrin PF00637.20 KPA45068.1 - 0.48 10.3 3.6 32 4.4 0.1 4.0 4 0 0 4 4 4 0 Region in Clathrin and VPS Egg_lysin PF01303.17 KPA45068.1 - 1.4 9.2 5.4 0.45 10.7 0.3 2.8 3 1 0 4 4 4 0 Egg lysin (Sperm-lysin) HAT PF02184.16 KPA45068.1 - 2.9 8.0 19.3 24 5.0 3.1 7.8 9 1 0 9 9 8 0 HAT (Half-A-TPR) repeat Tannase PF07519.11 KPA45069.1 - 0.014 14.3 0.0 0.014 14.3 0.0 1.0 1 0 0 1 1 1 0 Tannase and feruloyl esterase PolyA_pol PF01743.20 KPA45071.1 - 1.7e-25 89.9 0.2 5e-25 88.4 0.2 1.8 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KPA45071.1 - 3e-11 42.9 0.4 7.2e-11 41.7 0.4 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KPA45071.1 - 0.0039 17.2 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative STI1 PF17830.1 KPA45071.1 - 0.024 14.6 0.0 0.12 12.4 0.0 2.2 1 0 0 1 1 1 0 STI1 domain Tti2 PF10521.9 KPA45072.1 - 6.6e-79 265.4 0.1 9.5e-79 264.8 0.1 1.2 1 0 0 1 1 1 1 Tti2 family HEAT PF02985.22 KPA45072.1 - 0.032 14.5 0.0 0.12 12.7 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat CysG_dimeriser PF10414.9 KPA45072.1 - 0.092 12.5 0.0 0.33 10.7 0.0 2.0 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region TetR_C_20 PF17925.1 KPA45072.1 - 0.2 12.0 2.1 6.3 7.2 0.2 3.2 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Syja_N PF02383.18 KPA45073.1 - 5.2e-76 256.0 0.0 9e-76 255.2 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain DUF5526 PF17664.1 KPA45073.1 - 0.005 16.4 2.2 0.0087 15.6 2.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5526) Sec7 PF01369.20 KPA45074.1 - 5.8e-65 218.4 0.1 1.1e-64 217.5 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KPA45074.1 - 3.4e-15 56.3 0.0 2.2e-14 53.7 0.0 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KPA45074.1 - 0.00023 20.9 0.0 0.00093 18.9 0.0 2.0 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF4378 PF14309.6 KPA45074.1 - 0.13 12.7 0.1 0.85 10.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) Anp1 PF03452.14 KPA45075.1 - 4.4e-114 380.3 0.3 9e-114 379.3 0.0 1.6 2 0 0 2 2 2 1 Anp1 NinG PF05766.12 KPA45075.1 - 0.15 12.0 3.7 0.3 11.0 3.7 1.5 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein RNase_PH PF01138.21 KPA45077.1 - 4e-27 95.3 0.0 6.5e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Activator-TraM PF11657.8 KPA45077.1 - 0.1 12.5 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Transcriptional activator TraM TMP_2 PF06791.13 KPA45077.1 - 0.44 10.2 2.4 0.42 10.2 0.3 1.8 2 0 0 2 2 2 0 Prophage tail length tape measure protein zf-C3HC4_3 PF13920.6 KPA45078.1 - 6.6e-09 35.5 12.7 1.1e-08 34.8 12.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPA45078.1 - 0.042 13.7 13.0 0.075 12.9 13.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2568 PF10823.8 KPA45078.1 - 2.4 8.5 5.4 0.52 10.6 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) Inhibitor_I78 PF11720.8 KPA45079.1 - 3.1e-08 33.5 0.0 3.7e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KPA45079.1 - 0.013 16.1 0.0 0.018 15.7 0.0 1.3 1 0 0 1 1 1 0 Potato inhibitor I family Pre-PUA PF17832.1 KPA45080.1 - 1.7e-20 73.5 0.7 2.4e-20 73.0 0.7 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KPA45080.1 - 2.1e-11 43.6 0.1 3.4e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 PUA domain DUF4267 PF14087.6 KPA45081.1 - 1.5e-25 89.5 0.3 1.7e-25 89.3 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF2688 PF10892.8 KPA45082.1 - 0.046 13.2 0.1 0.16 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) FA_desaturase PF00487.24 KPA45085.1 - 6.6e-11 42.5 27.0 9.3e-11 42.0 27.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase COesterase PF00135.28 KPA45086.1 - 1e-57 196.2 0.1 1.3e-57 195.9 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA45086.1 - 1.2e-09 38.4 0.7 0.00062 19.7 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA45086.1 - 0.14 11.7 0.3 0.31 10.5 0.1 1.7 1 1 1 2 2 2 0 Prolyl oligopeptidase family Retrotran_gag_2 PF14223.6 KPA45087.1 - 4.7e-06 26.3 0.0 8.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KPA45087.1 - 7.7e-05 22.5 9.4 0.00017 21.4 2.7 2.5 2 0 0 2 2 2 2 GAG-pre-integrase domain zf-CCHC PF00098.23 KPA45087.1 - 0.53 10.5 4.0 1.5 9.1 4.0 1.8 1 0 0 1 1 1 0 Zinc knuckle adh_short PF00106.25 KPA45088.1 - 1.8e-05 24.3 0.1 2.6e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA45088.1 - 0.0026 17.4 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 KPA45088.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amino_oxidase PF01593.24 KPA45089.1 - 7.1e-29 101.4 0.0 1.1e-28 100.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA45089.1 - 0.00011 22.3 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF4403 PF14356.6 KPA45089.1 - 0.028 13.1 0.1 0.05 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) TOM20_plant PF06552.12 KPA45089.1 - 0.034 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2167 PF09935.9 KPA45089.1 - 0.058 12.6 0.1 0.12 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) F-box-like PF12937.7 KPA45090.1 - 0.0001 22.1 2.3 0.0003 20.6 0.7 2.6 3 0 0 3 3 3 1 F-box-like Oxysterol_BP PF01237.18 KPA45091.1 - 1.7e-57 195.0 0.0 6.2e-49 166.8 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein UDPGT PF00201.18 KPA45092.1 - 2.3e-09 36.6 0.0 3.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PHO4 PF01384.20 KPA45093.1 - 1.6 7.7 15.3 0.034 13.2 3.3 2.3 2 1 0 2 2 2 0 Phosphate transporter family 7TM_GPCR_Srz PF10325.9 KPA45093.1 - 3 7.1 14.1 0.1 11.9 6.7 2.2 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz WD40 PF00400.32 KPA45094.1 - 4.7e-16 58.9 6.0 9.1e-07 29.5 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KPA45094.1 - 1.9e-13 50.5 0.1 5.4e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KPA45094.1 - 3.4e-09 36.9 1.6 0.00019 21.7 0.1 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Alfin PF12165.8 KPA45094.1 - 0.063 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Alfin DUF3246 PF11596.8 KPA45094.1 - 0.16 11.4 4.1 0.38 10.2 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Thioredoxin PF00085.20 KPA45095.1 - 1.4e-21 76.4 0.0 1.8e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KPA45095.1 - 1e-06 28.4 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KPA45095.1 - 1.5e-05 24.7 0.0 1.9e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KPA45095.1 - 2.8e-05 24.5 0.1 5.6e-05 23.6 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KPA45095.1 - 0.0075 16.6 0.0 0.031 14.6 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_5 PF13743.6 KPA45095.1 - 0.026 14.2 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KPA45095.1 - 0.067 13.4 0.0 0.098 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like WD40 PF00400.32 KPA45096.1 - 4.3e-21 74.8 3.5 4.9e-05 24.0 0.0 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA45096.1 - 0.00012 22.3 0.1 2.8 8.3 0.0 4.3 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA45096.1 - 0.00026 20.1 0.7 0.0082 15.1 0.0 2.9 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eRF1_1 PF03463.15 KPA45097.1 - 6e-43 145.9 0.0 1e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KPA45097.1 - 3.4e-18 66.2 0.1 6.1e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KPA45097.1 - 1.3e-15 57.8 0.0 2.6e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.21 KPA45098.1 - 1.6e-35 122.7 0.0 2.1e-24 86.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Dev_Cell_Death PF10539.9 KPA45098.1 - 0.21 11.4 0.0 0.57 10.1 0.0 1.7 2 0 0 2 2 2 0 Development and cell death domain zf-RING_UBOX PF13445.6 KPA45100.1 - 0.00025 21.0 1.0 0.00085 19.3 1.0 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KPA45100.1 - 0.0019 18.0 4.4 0.021 14.7 0.4 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KPA45100.1 - 0.0024 17.8 4.5 0.0028 17.6 0.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KPA45100.1 - 0.018 14.9 0.6 0.018 14.9 0.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA45100.1 - 0.12 12.3 3.0 0.33 10.8 2.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPA45100.1 - 0.13 12.1 4.3 0.16 11.9 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA45100.1 - 0.22 11.9 5.8 0.16 12.3 0.7 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 KPA45100.1 - 0.79 9.9 3.6 0.97 9.6 0.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prp19 PF08606.11 KPA45101.1 - 8.7e-32 108.9 2.8 8.7e-32 108.9 2.8 1.9 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.32 KPA45101.1 - 2.7e-11 43.8 0.0 0.081 13.8 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA45101.1 - 3.7e-11 43.2 0.0 0.017 15.4 0.0 4.3 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPA45101.1 - 3.8e-06 26.9 0.0 0.005 16.7 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KPA45101.1 - 0.0014 17.8 0.0 0.082 11.9 0.0 2.1 1 1 1 2 2 2 1 Coatomer WD associated region V_ATPase_I_N PF18670.1 KPA45101.1 - 0.0015 18.9 1.0 0.0029 18.0 0.4 1.8 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain VID27 PF08553.10 KPA45101.1 - 0.0031 16.6 0.1 0.0051 15.9 0.1 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain zf-Nse PF11789.8 KPA45101.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KPA45101.1 - 0.023 14.9 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 U-box domain VPS9 PF02204.18 KPA45101.1 - 0.024 14.8 0.0 0.068 13.4 0.0 1.7 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain Frtz PF11768.8 KPA45101.1 - 0.21 9.8 0.0 3 6.1 0.0 1.9 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KPA45101.1 - 0.25 10.6 0.0 4.5 6.5 0.0 2.1 1 1 1 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 KPA45101.1 - 0.31 10.0 0.8 2.9 6.7 0.1 2.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein OHCU_decarbox PF09349.10 KPA45102.1 - 4.7e-40 137.6 0.0 5.2e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DUF4449 PF14613.6 KPA45104.1 - 1.4e-05 25.2 1.6 4.6e-05 23.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) DUF445 PF04286.12 KPA45104.1 - 1.6 8.4 8.4 11 5.7 8.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF445) 4HBT_3 PF13622.6 KPA45105.1 - 1.6e-24 87.5 0.0 2.1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily NMO PF03060.15 KPA45107.1 - 1.2e-31 110.3 4.8 7.8e-25 87.9 3.2 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KPA45107.1 - 7.5e-07 28.5 0.2 3.9e-05 22.8 0.2 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KPA45107.1 - 3.3e-05 23.1 4.2 4.9e-05 22.5 4.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KPA45107.1 - 0.00015 21.1 0.1 0.00024 20.4 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase COX5B PF01215.19 KPA45108.1 - 2.8e-56 188.7 0.0 3.8e-56 188.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 KPA45108.1 - 0.019 14.8 0.3 4.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DUF4604 PF15377.6 KPA45109.1 - 1.8e-32 113.1 19.9 2.1e-32 112.9 19.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF2283 PF10049.9 KPA45109.1 - 0.014 15.6 0.3 0.035 14.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2283) Glyco_transf_15 PF01793.16 KPA45110.1 - 4e-95 318.8 8.7 2.9e-94 316.0 8.7 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L27A PF00828.19 KPA45111.1 - 6.9e-34 117.3 0.6 1.2e-33 116.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Metallophos PF00149.28 KPA45111.1 - 1.5e-06 28.9 0.0 4.2e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPA45111.1 - 0.00011 22.5 0.0 0.0046 17.2 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PX PF00787.24 KPA45112.1 - 3e-18 65.8 0.0 5.5e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 PX domain ILVD_EDD PF00920.21 KPA45113.1 - 3e-212 705.9 0.4 3.4e-212 705.6 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family Myb_DNA-bind_6 PF13921.6 KPA45114.1 - 5.2e-05 23.4 0.2 0.079 13.2 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KPA45114.1 - 0.0031 17.7 0.2 0.067 13.4 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KPA45115.1 - 1.6e-17 63.4 2.3 4e-10 39.7 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPA45115.1 - 9.9e-10 38.5 0.9 0.00019 21.6 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Glyco_hydro_16 PF00722.21 KPA45116.1 - 8.7e-46 155.6 3.4 1.5e-45 154.9 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RXT2_N PF08595.11 KPA45116.1 - 0.99 9.4 7.3 1.9 8.5 7.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF1387 PF07139.11 KPA45116.1 - 5.3 6.7 14.9 7.5 6.2 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Lactonase PF10282.9 KPA45117.1 - 7.3e-63 212.9 0.0 9.4e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 KPA45117.1 - 0.0012 17.4 0.0 0.14 10.6 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain APH PF01636.23 KPA45118.1 - 1.7e-06 28.1 0.6 4.4e-05 23.5 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KPA45118.1 - 3.2e-05 23.4 0.0 5.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KPA45118.1 - 0.00032 20.2 0.1 0.0005 19.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KPA45118.1 - 0.00078 18.3 0.1 0.0011 17.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KPA45118.1 - 0.0058 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 KPA45118.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 WaaY PF06176.11 KPA45118.1 - 0.092 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kinase-like PF14531.6 KPA45118.1 - 0.2 11.0 0.0 0.42 9.9 0.0 1.4 2 0 0 2 2 2 0 Kinase-like SQS_PSY PF00494.19 KPA45119.1 - 8.8e-57 192.6 0.0 1.2e-56 192.1 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Ribosomal_S6 PF01250.17 KPA45119.1 - 3e-24 85.1 0.0 5.3e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6 Peptidase_M24 PF00557.24 KPA45119.1 - 0.021 14.5 0.1 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 Metallopeptidase family M24 Cullin_binding PF03556.15 KPA45120.1 - 2e-34 118.6 7.0 4e-34 117.6 7.0 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KPA45120.1 - 6.5e-13 48.3 0.0 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain PASTA PF03793.19 KPA45120.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 PASTA domain PTCB-BRCT PF12738.7 KPA45121.1 - 5.8e-42 141.5 1.6 1.5e-17 63.3 0.0 4.4 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KPA45121.1 - 4e-33 113.6 0.0 9.8e-09 35.5 0.0 4.5 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KPA45121.1 - 1.6e-18 66.9 0.0 1e-05 25.8 0.0 4.5 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KPA45121.1 - 3e-08 33.8 0.0 0.053 13.8 0.0 4.1 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KPA45121.1 - 0.0011 18.8 0.0 5.2 7.0 0.0 4.0 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KPA45121.1 - 0.03 14.4 0.0 2.6 8.1 0.0 3.2 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Herpes_pp85 PF04637.12 KPA45121.1 - 0.2 10.1 0.0 0.34 9.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3716 PF12511.8 KPA45122.1 - 1.3e-08 34.7 8.7 2.3e-08 33.9 8.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) TMCO5 PF14992.6 KPA45122.1 - 0.31 10.6 8.5 0.02 14.5 0.8 2.1 2 0 0 2 2 2 0 TMCO5 family Snapin_Pallidin PF14712.6 KPA45122.1 - 0.38 11.2 3.8 0.4 11.1 2.1 2.0 2 0 0 2 2 2 0 Snapin/Pallidin DLP_helical PF18709.1 KPA45122.1 - 0.52 9.5 4.2 0.49 9.5 1.3 2.0 1 1 1 2 2 2 0 Dynamin-like helical domain ERM PF00769.19 KPA45122.1 - 8.4 6.1 20.3 0.012 15.5 3.9 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Chs7 PF12271.8 KPA45123.1 - 3.3e-125 417.2 11.0 3.7e-125 417.0 11.0 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 KPA45123.1 - 0.013 15.8 0.6 0.013 15.8 0.6 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) DUF4281 PF14108.6 KPA45123.1 - 1.4 9.3 9.1 0.077 13.4 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) Cyclin PF08613.11 KPA45124.1 - 3e-10 40.7 0.5 6e-10 39.7 0.5 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KPA45124.1 - 0.00012 21.8 0.3 0.00021 21.0 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain AAA PF00004.29 KPA45126.1 - 6.5e-07 29.8 1.1 7.4e-06 26.4 1.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KPA45126.1 - 0.0012 18.8 0.2 0.055 13.4 0.0 3.3 3 1 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 KPA45126.1 - 0.0017 18.7 0.0 0.0053 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KPA45126.1 - 0.0051 16.1 0.0 0.0088 15.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KPA45126.1 - 0.0067 17.0 0.0 0.031 14.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KPA45126.1 - 0.012 15.9 0.1 0.027 14.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KPA45126.1 - 0.022 15.0 1.3 0.055 13.8 0.2 2.3 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KPA45126.1 - 0.035 13.2 0.0 0.079 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 KPA45126.1 - 0.088 12.6 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 KPA45126.1 - 0.14 11.4 1.2 0.18 11.0 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KPA45126.1 - 0.61 10.5 7.6 0.27 11.7 0.7 2.8 2 1 0 2 2 2 0 AAA domain Utp8 PF10395.9 KPA45127.1 - 1.1e-06 27.5 4.6 6.1e-06 25.1 2.6 2.4 2 1 0 2 2 2 1 Utp8 family Phage_connect_1 PF05135.13 KPA45128.1 - 0.0034 17.9 0.3 3.9 8.0 0.1 2.6 2 0 0 2 2 2 2 Phage gp6-like head-tail connector protein ATP13 PF12921.7 KPA45129.1 - 2e-14 53.4 0.0 5.5e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial ATPase expression LSM PF01423.22 KPA45130.1 - 8.7e-19 67.0 0.2 1e-18 66.8 0.2 1.1 1 0 0 1 1 1 1 LSM domain GTP_EFTU PF00009.27 KPA45131.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KPA45131.1 - 1.8e-10 41.1 1.2 8.3e-10 38.9 0.7 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KPA45131.1 - 1.7e-05 25.1 0.0 5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KPA45131.1 - 0.001 19.2 0.2 0.0045 17.1 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA45131.1 - 0.0074 16.2 2.4 1.8 8.4 1.3 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KPA45131.1 - 0.062 13.4 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 KPA45131.1 - 0.091 13.0 0.2 0.74 10.0 0.1 2.4 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 KPA45131.1 - 0.12 12.1 0.3 2.4 7.9 0.1 2.8 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Arrestin_C PF02752.22 KPA45132.1 - 1.1e-16 61.5 0.0 5.2e-16 59.3 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KPA45132.1 - 2e-07 31.1 0.6 0.0093 16.0 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain MFS_1 PF07690.16 KPA45133.1 - 1.1e-35 123.2 49.0 1.1e-35 123.2 49.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA45133.1 - 0.00034 19.6 14.9 0.00034 19.6 14.9 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter NUDIX PF00293.28 KPA45134.1 - 4.6e-17 62.3 0.1 7.3e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KPA45134.1 - 8.5e-06 25.7 0.1 5.8e-05 23.0 0.1 2.1 1 1 0 1 1 1 1 NUDIX domain Fungal_trans PF04082.18 KPA45135.1 - 2e-18 66.4 0.0 3.5e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPA45135.1 - 3.6e-09 36.6 13.5 0.00023 21.5 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPA45135.1 - 9.9e-07 28.9 6.8 9.9e-07 28.9 6.8 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPA45135.1 - 0.00015 22.3 13.0 0.03 15.1 2.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KPA45135.1 - 0.58 9.8 2.6 2.1 8.1 0.0 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain CAP PF00188.26 KPA45136.1 - 3.7e-18 66.6 0.2 5.2e-18 66.1 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family LSM PF01423.22 KPA45137.1 - 5.9e-14 51.5 0.1 1.2e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KPA45137.1 - 0.024 14.3 0.1 0.046 13.4 0.1 1.4 1 0 0 1 1 1 0 Hfq protein Zn_clus PF00172.18 KPA45138.1 - 0.022 14.9 12.4 0.22 11.7 12.4 2.4 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M13_N PF05649.13 KPA45139.1 - 1.7e-72 245.3 0.1 2.2e-72 244.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KPA45139.1 - 1.1e-62 211.2 0.0 2.1e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 SabA_adhesion PF18304.1 KPA45139.1 - 0.059 12.6 0.2 0.096 11.9 0.2 1.3 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain ABC_tran PF00005.27 KPA45140.1 - 6.1e-33 114.2 0.0 1.8e-32 112.7 0.0 1.9 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KPA45140.1 - 2.8e-18 66.6 5.9 2.8e-18 66.6 5.9 2.1 3 0 0 3 3 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KPA45140.1 - 0.00039 19.9 0.0 0.0017 17.9 0.0 2.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KPA45140.1 - 0.00054 19.9 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 KPA45140.1 - 0.012 15.2 0.1 0.039 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KPA45140.1 - 0.023 14.5 0.1 0.054 13.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KPA45140.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KPA45140.1 - 0.064 13.0 0.0 0.22 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KPA45140.1 - 0.078 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase MTABC_N PF16185.5 KPA45140.1 - 0.22 11.0 0.0 0.22 11.0 0.0 2.1 3 0 0 3 3 3 0 Mitochondrial ABC-transporter N-terminal five TM region DUF2484 PF10658.9 KPA45140.1 - 1.3 9.4 5.7 3.3 8.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) SbcCD_C PF13558.6 KPA45140.1 - 1.7 8.9 4.0 3.8 7.8 0.2 3.4 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit bZIP_1 PF00170.21 KPA45141.1 - 1.2e-11 44.5 3.0 2e-11 43.8 3.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPA45141.1 - 0.0001 22.3 1.7 0.00018 21.5 1.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KPA45141.1 - 0.0039 17.7 2.1 0.0066 16.9 2.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Lzipper-MIP1 PF14389.6 KPA45141.1 - 0.11 12.8 0.1 0.38 11.1 0.0 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Aldo_ket_red PF00248.21 KPA45142.1 - 4.4e-78 262.4 0.0 5e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_1 PF00583.25 KPA45143.1 - 0.0013 18.9 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPA45143.1 - 0.051 13.5 0.0 0.28 11.1 0.0 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Vps35 PF03635.17 KPA45145.1 - 0 1033.9 0.6 0 1033.6 0.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF5427 PF10310.9 KPA45145.1 - 3.6 6.4 9.2 5.9 5.7 9.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) TFR_dimer PF04253.15 KPA45146.1 - 9.5e-29 100.0 0.0 1.8e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KPA45146.1 - 1.3e-15 57.6 0.1 2.3e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KPA45146.1 - 4.5e-12 45.8 0.1 9.8e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 PA domain Cyt-b5 PF00173.28 KPA45147.1 - 1e-13 51.2 0.0 1.5e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1768 PF08719.11 KPA45148.1 - 4.1e-45 153.9 0.0 4.6e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Tim44 PF04280.15 KPA45149.1 - 5.5e-35 120.6 0.2 1.2e-34 119.6 0.0 1.7 2 0 0 2 2 2 1 Tim44-like domain Zip PF02535.22 KPA45149.1 - 1.7 7.8 5.2 2.6 7.2 5.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_S11 PF00411.19 KPA45150.1 - 9.7e-10 38.8 0.0 2.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S11 RWD PF05773.22 KPA45150.1 - 0.045 14.0 0.0 0.076 13.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain DUF4169 PF13770.6 KPA45150.1 - 0.15 12.3 1.1 0.55 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) Peptidase_C97 PF05903.14 KPA45151.1 - 5.6e-35 120.4 0.0 7.6e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KPA45151.1 - 0.012 15.9 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF4632 PF15451.6 KPA45151.1 - 0.32 11.1 2.0 0.53 10.4 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) YchF-GTPase_C PF06071.13 KPA45152.1 - 3.9e-36 123.1 0.1 1.4e-35 121.4 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KPA45152.1 - 1.5e-16 60.5 0.0 3.4e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPA45152.1 - 0.00024 20.7 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KPA45152.1 - 0.0025 17.8 0.0 0.0064 16.5 0.0 1.7 1 0 0 1 1 1 1 TGS domain BetaGal_dom3 PF13363.6 KPA45152.1 - 0.034 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 AAA_14 PF13173.6 KPA45152.1 - 0.036 14.1 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KPA45152.1 - 0.11 13.1 0.0 1.8 9.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KPA45152.1 - 0.12 12.5 0.1 5.2 7.1 0.0 2.6 1 1 1 2 2 2 0 Dynamin family VPS9 PF02204.18 KPA45154.1 - 8.4e-18 64.5 0.1 1.8e-17 63.5 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 KPA45154.1 - 8.6e-18 64.2 0.1 1e-13 51.2 0.0 5.2 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA45154.1 - 5.1e-14 52.6 0.9 0.00016 22.2 0.1 4.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA45154.1 - 1.7e-08 34.8 0.3 0.075 13.6 0.0 5.2 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA45154.1 - 5.3e-06 26.4 0.0 0.68 10.7 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KPA45154.1 - 0.00022 21.5 0.4 30 5.3 0.0 5.3 5 0 0 5 5 5 0 Ankyrin repeat PX PF00787.24 KPA45154.1 - 0.055 13.4 0.2 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 PX domain AA_permease PF00324.21 KPA45156.1 - 2.2e-119 399.2 43.2 2.6e-119 399.0 43.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA45156.1 - 4.2e-30 104.9 46.9 5.5e-30 104.5 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2263 PF10021.9 KPA45157.1 - 5.8e-23 81.9 0.0 1e-22 81.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KPA45157.1 - 0.027 14.5 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Macro domain BCS1_N PF08740.11 KPA45158.1 - 1.6e-40 139.1 0.0 2.2e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KPA45158.1 - 1.3e-17 64.4 0.0 2.4e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KPA45158.1 - 0.00026 20.5 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 KPA45158.1 - 0.00068 19.4 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KPA45158.1 - 0.0022 18.0 0.0 0.0053 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPA45158.1 - 0.0034 17.8 0.0 0.0081 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA45158.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KPA45158.1 - 0.01 15.4 0.0 0.057 13.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KPA45158.1 - 0.012 16.1 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KPA45158.1 - 0.014 15.6 0.0 0.077 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KPA45158.1 - 0.027 15.0 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KPA45158.1 - 0.037 13.8 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KPA45158.1 - 0.042 13.8 0.1 1 9.2 0.0 2.6 3 0 0 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 KPA45158.1 - 0.097 12.4 0.0 0.23 11.2 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 KPA45158.1 - 0.11 12.9 0.0 0.44 11.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 KPA45158.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF815 PF05673.13 KPA45158.1 - 0.12 11.5 0.0 0.27 10.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KPA45158.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 KPA45158.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KPA45158.1 - 0.2 12.0 0.0 0.44 11.0 0.0 1.6 1 1 0 1 1 1 0 RNA helicase F_bP_aldolase PF01116.20 KPA45159.1 - 1.2e-92 310.3 0.0 1.4e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Oxysterol_BP PF01237.18 KPA45160.1 - 3.1e-61 207.3 0.5 4.9e-59 200.0 0.5 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF1579 PF07617.11 KPA45160.1 - 0.03 14.2 0.0 0.84 9.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1579) Methyltransf_25 PF13649.6 KPA45161.1 - 4.9e-16 59.2 0.0 1.6e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA45161.1 - 6.8e-15 55.5 0.0 1.4e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA45161.1 - 1.3e-12 47.8 0.0 1.8e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA45161.1 - 3.2e-11 43.3 0.0 3.9e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA45161.1 - 2.2e-09 38.0 0.0 3.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA45161.1 - 6.1e-06 25.7 0.0 7.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KPA45161.1 - 1.2e-05 24.9 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KPA45161.1 - 4.3e-05 23.1 0.0 6.3e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KPA45161.1 - 0.0011 18.4 0.0 0.0051 16.3 0.0 2.0 2 1 0 2 2 2 1 Tellurite resistance protein TehB PCMT PF01135.19 KPA45161.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KPA45161.1 - 0.054 13.2 0.1 0.089 12.5 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase ADH_zinc_N PF00107.26 KPA45161.1 - 0.055 13.5 0.1 0.24 11.4 0.0 2.1 2 1 0 2 2 2 0 Zinc-binding dehydrogenase MetW PF07021.12 KPA45161.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 KPA45161.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain rve_3 PF13683.6 KPA45161.1 - 0.19 11.6 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 Integrase core domain Cellulase PF00150.18 KPA45162.1 - 1.9e-11 43.9 0.6 1.9e-11 43.9 0.6 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TMEM51 PF15345.6 KPA45162.1 - 0.043 13.6 0.1 0.043 13.6 0.1 2.2 2 1 0 2 2 2 0 Transmembrane protein 51 EphA2_TM PF14575.6 KPA45162.1 - 0.082 13.8 2.1 0.16 12.9 0.0 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SNARE PF05739.19 KPA45162.1 - 0.085 12.9 0.4 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 SNARE domain Transket_pyr PF02779.24 KPA45163.1 - 1e-44 152.3 0.0 1.7e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KPA45163.1 - 1.4e-32 112.2 0.2 3e-32 111.1 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KPA45163.1 - 0.0032 17.7 0.0 0.0062 16.8 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II F-actin_cap_A PF01267.17 KPA45164.1 - 3.3e-96 321.8 0.0 3.7e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Cyt-b5 PF00173.28 KPA45165.1 - 9.2e-25 86.6 0.1 1.5e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TFA2_Winged_2 PF18121.1 KPA45166.1 - 3.1e-21 74.8 0.0 6.4e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KPA45166.1 - 9.2e-13 48.3 0.0 1.9e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain DSBA PF01323.20 KPA45167.1 - 8.5e-23 81.1 0.0 1e-22 80.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain zf-C2H2 PF00096.26 KPA45168.1 - 1.2e-19 69.6 33.5 1.7e-05 25.0 0.2 5.5 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPA45168.1 - 1.6e-17 63.1 31.8 1.8e-06 28.1 1.9 5.8 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KPA45168.1 - 5.8e-08 32.8 2.5 0.04 14.2 0.3 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KPA45168.1 - 8.3e-08 32.4 35.7 0.012 16.4 0.2 5.7 6 0 0 6 6 5 4 C2H2-type zinc finger zf-met PF12874.7 KPA45168.1 - 0.0039 17.5 10.8 2.7 8.5 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KPA45168.1 - 0.024 14.8 0.7 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 KPA45168.1 - 0.12 13.0 0.5 0.12 13.0 0.5 3.7 2 1 2 4 4 3 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KPA45168.1 - 0.12 12.1 8.2 2.8 7.8 0.8 3.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-MYST PF17772.1 KPA45168.1 - 0.53 9.9 2.1 3.9 7.1 0.2 3.0 3 0 0 3 3 3 0 MYST family zinc finger domain C1_4 PF07975.12 KPA45168.1 - 0.58 10.4 3.5 17 5.7 0.0 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 KPA45168.1 - 5.4 7.2 9.0 9.9 6.4 0.3 3.2 1 1 3 4 4 4 0 Zinc ribbon domain DUF2256 PF10013.9 KPA45168.1 - 6.1 7.0 8.7 30 4.8 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KPA45168.1 - 9 6.3 10.9 4.3 7.3 0.2 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type VHS PF00790.19 KPA45169.1 - 2.3e-19 69.6 0.0 5.1e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KPA45169.1 - 1.2e-06 28.7 0.2 2.7e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 GAT domain SIKE PF05769.11 KPA45169.1 - 0.036 14.0 1.7 0.074 13.0 1.7 1.5 1 0 0 1 1 1 0 SIKE family SR-25 PF10500.9 KPA45169.1 - 0.057 13.0 11.8 0.099 12.2 11.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein tRNA-synt_1g PF09334.11 KPA45170.1 - 1.3e-138 462.1 2.0 1.6e-136 455.1 2.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KPA45170.1 - 2.3e-06 26.2 2.2 0.00033 19.1 0.0 3.5 5 0 0 5 5 5 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KPA45170.1 - 0.086 12.2 1.0 9.8 5.4 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain DDE_Tnp_IS66_C PF13817.6 KPA45170.1 - 0.15 12.3 0.1 0.84 9.9 0.0 2.3 2 0 0 2 2 2 0 IS66 C-terminal element DUF1168 PF06658.12 KPA45170.1 - 5.1 6.9 15.1 9.4 6.1 15.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) PEMT PF04191.13 KPA45171.1 - 1.1e-32 112.6 1.5 2.5e-32 111.4 0.9 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase RXT2_N PF08595.11 KPA45172.1 - 1.1e-47 162.0 0.0 1.1e-47 162.0 0.0 2.8 3 1 0 3 3 3 1 RXT2-like, N-terminal Sugar_tr PF00083.24 KPA45173.1 - 3.3e-92 309.7 23.5 3.7e-92 309.6 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA45173.1 - 3.3e-28 98.7 23.7 3.3e-28 98.7 23.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Steroid_dh PF02544.16 KPA45173.1 - 0.08 12.9 1.4 2 8.4 0.8 2.7 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2530 PF10745.9 KPA45173.1 - 1.1 9.6 5.1 0.97 9.7 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Glyco_hydro_31 PF01055.26 KPA45174.1 - 3.3e-105 352.8 0.5 4.2e-105 352.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KPA45174.1 - 2.1e-13 50.4 0.2 7.3e-13 48.6 0.2 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_hydro_3 PF00933.21 KPA45175.1 - 1.5e-56 192.1 0.0 2e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KPA45175.1 - 5.9e-53 179.9 1.5 3.1e-52 177.5 0.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KPA45175.1 - 9.4e-23 80.1 0.8 2.1e-22 79.0 0.8 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 KPA45175.1 - 0.039 14.3 1.1 0.26 11.6 0.1 2.7 2 1 0 3 3 3 0 Domain of unknown function DUF11 PAS_2 PF08446.11 KPA45176.1 - 1.1e-09 38.9 0.0 2.9e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KPA45176.1 - 0.0031 17.7 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 KPA45176.1 - 0.058 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold PHY PF00360.20 KPA45177.1 - 2.2e-28 98.8 0.0 5.4e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KPA45177.1 - 2.1e-18 66.8 0.1 4.7e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPA45177.1 - 5.1e-17 62.0 0.0 4e-16 59.2 0.0 2.3 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 KPA45177.1 - 7e-13 49.4 0.0 2.3e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KPA45177.1 - 9.5e-13 48.0 1.9 3.4e-12 46.2 1.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KPA45177.1 - 0.004 17.1 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KPA45177.1 - 0.028 14.2 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CK_II_beta PF01214.18 KPA45178.1 - 4.6e-75 251.4 0.0 1.2e-74 250.1 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Pox_Ag35 PF03286.14 KPA45178.1 - 0.017 14.9 4.7 0.14 12.0 2.9 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RRN3 PF05327.11 KPA45178.1 - 0.05 12.2 2.4 0.07 11.7 2.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Radial_spoke PF04712.12 KPA45178.1 - 0.7 8.8 6.4 0.99 8.3 6.4 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein CDC45 PF02724.14 KPA45178.1 - 1.5 7.0 6.7 2.4 6.3 6.7 1.3 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 KPA45178.1 - 4.5 7.7 10.8 7.3 7.0 3.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 KPA45178.1 - 9.9 4.1 8.0 15 3.5 8.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cupin_8 PF13621.6 KPA45179.1 - 5.2e-25 88.6 0.0 6.2e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KPA45179.1 - 0.0014 19.1 0.0 0.011 16.1 0.0 2.5 3 1 0 3 3 3 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KPA45179.1 - 0.0023 17.5 0.1 0.0061 16.1 0.1 1.7 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 KPA45179.1 - 0.013 15.2 0.0 0.043 13.5 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Sec16_N PF12935.7 KPA45179.1 - 0.053 13.7 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus Ran-binding PF05508.11 KPA45181.1 - 5.7e-114 380.3 0.0 7.8e-114 379.9 0.0 1.2 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.27 KPA45182.1 - 9e-43 146.1 0.0 1.6e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KPA45182.1 - 4.2e-30 104.3 1.8 4.6e-30 104.2 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KPA45182.1 - 3.6e-07 30.5 1.0 6.6e-07 29.6 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KPA45182.1 - 0.0012 18.9 0.0 0.0071 16.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Hamartin PF04388.12 KPA45182.1 - 0.67 8.5 2.3 0.93 8.1 2.3 1.1 1 0 0 1 1 1 0 Hamartin protein PEPCK_ATP PF01293.20 KPA45183.1 - 1.5e-215 716.2 0.0 1.8e-215 716.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KPA45183.1 - 0.19 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KPA45183.1 - 0.22 11.9 0.0 0.38 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SNF2_N PF00176.23 KPA45184.1 - 2.5e-68 230.3 2.7 2.6e-66 223.7 2.7 2.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA45184.1 - 1.1e-16 61.2 0.1 4.1e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA45184.1 - 1.8e-06 28.0 1.3 3.4e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPA45184.1 - 4.4e-06 26.6 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase UPF0139 PF03669.13 KPA45185.1 - 7.3e-10 38.6 0.0 9.4e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Robl_LC7 PF03259.17 KPA45187.1 - 5.3e-09 35.7 0.0 6.2e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.8 KPA45188.1 - 1.1e-26 93.3 0.0 1.1e-26 93.3 0.0 2.3 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation DEAD PF00270.29 KPA45189.1 - 3.5e-43 147.4 0.0 6.6e-43 146.5 0.0 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA45189.1 - 6.6e-27 94.1 0.4 1.7e-26 92.7 0.0 1.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KPA45189.1 - 0.13 11.0 0.0 5.2 5.7 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SecA_DEAD PF07517.14 KPA45189.1 - 0.21 10.8 0.2 0.84 8.9 0.0 1.9 2 0 0 2 2 2 0 SecA DEAD-like domain Aldedh PF00171.22 KPA45190.1 - 4.8e-118 394.6 0.0 5.9e-118 394.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BAAT_C PF08840.11 KPA45190.1 - 0.053 13.4 3.1 0.27 11.1 0.0 2.5 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal PhoLip_ATPase_C PF16212.5 KPA45191.1 - 1.5e-77 260.7 29.1 1.5e-77 260.7 29.1 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KPA45191.1 - 2.5e-19 68.7 1.2 9.1e-19 66.9 1.2 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KPA45191.1 - 4.3e-14 52.4 0.1 6.2e-13 48.6 0.0 2.8 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPA45191.1 - 1.1e-09 38.9 3.2 8.5e-06 26.2 0.6 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KPA45191.1 - 0.0055 16.3 0.1 0.027 14.0 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KPA45191.1 - 0.016 15.0 0.4 0.035 13.9 0.4 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF5007 PF16398.5 KPA45192.1 - 0.036 13.8 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5007) BLM10_mid PF16507.5 KPA45192.1 - 0.1 11.2 0.1 0.26 9.9 0.0 1.6 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, mid region FAM178 PF14816.6 KPA45192.1 - 0.15 11.0 1.0 0.25 10.3 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 vATP-synt_E PF01991.18 KPA45193.1 - 3e-67 225.9 13.1 3.5e-67 225.7 13.1 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit FliH PF02108.16 KPA45193.1 - 0.00058 19.9 0.3 0.0061 16.6 0.0 2.5 1 1 2 3 3 3 1 Flagellar assembly protein FliH Methyltransf_7 PF03492.15 KPA45193.1 - 0.031 13.5 3.3 0.22 10.7 4.0 1.8 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase KxDL PF10241.9 KPA45193.1 - 0.047 14.0 2.4 0.047 14.0 2.4 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein NTS PF15447.6 KPA45193.1 - 0.4 11.2 7.0 0.3 11.6 1.4 2.8 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 Mg_trans_NIPA PF05653.14 KPA45194.1 - 4.3e-14 52.3 10.6 7.9e-14 51.5 10.6 1.3 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KPA45194.1 - 2.5e-06 27.7 11.2 0.00034 20.8 0.1 2.6 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KPA45194.1 - 0.00013 21.3 4.8 0.00013 21.3 4.8 2.1 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport DUF563 PF04577.14 KPA45196.1 - 0.16 12.1 0.1 0.59 10.2 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF563) DUF1501 PF07394.12 KPA45196.1 - 0.17 10.9 1.4 0.25 10.4 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF3433 PF11915.8 KPA45197.1 - 2.5e-30 104.8 23.8 2.5e-28 98.3 4.2 4.3 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Pirin PF02678.16 KPA45198.1 - 1.9e-25 88.9 0.7 4.6e-25 87.7 0.7 1.6 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KPA45198.1 - 1.8 8.3 6.3 0.77 9.5 0.5 3.1 3 1 0 3 3 3 0 Cupin domain Glyco_hydro_18 PF00704.28 KPA45199.1 - 4.5e-16 59.5 1.3 1.5e-15 57.8 1.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 BAF1_ABF1 PF04684.13 KPA45199.1 - 0.068 12.2 3.7 0.092 11.8 3.7 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Oxysterol_BP PF01237.18 KPA45200.1 - 1.5e-134 448.5 0.0 1.5e-133 445.2 0.0 2.1 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 KPA45200.1 - 8.6e-17 61.0 0.1 4e-10 39.8 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA45200.1 - 3.6e-16 59.5 0.0 2.9e-09 37.4 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KPA45200.1 - 4.5e-14 52.2 0.3 0.00021 21.6 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KPA45200.1 - 7e-14 50.6 0.1 4.7e-05 23.5 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.29 KPA45200.1 - 4.4e-12 46.4 0.9 9.4e-12 45.4 0.9 1.6 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 KPA45200.1 - 9.7e-12 45.2 0.0 1.1e-06 29.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH_8 PF15409.6 KPA45200.1 - 1.6e-07 31.5 1.8 2.3e-07 31.0 0.7 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KPA45200.1 - 5.5e-05 23.5 2.6 7e-05 23.2 1.3 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_17 PF18012.1 KPA45200.1 - 0.016 14.9 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 PH domain 4HBT_3 PF13622.6 KPA45201.1 - 3.8e-81 273.0 2.4 4.4e-81 272.8 2.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KPA45201.1 - 2.1e-24 85.9 0.0 1.5e-10 41.0 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Asp PF00026.23 KPA45203.1 - 2.1e-64 218.0 0.6 2.9e-63 214.2 0.6 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA45203.1 - 1.2e-12 48.4 0.4 3e-11 43.9 0.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KPA45203.1 - 0.0099 16.4 0.0 0.3 11.7 0.0 2.9 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KPA45203.1 - 0.017 15.8 1.0 1.5 9.5 0.2 3.3 3 1 0 3 3 3 0 Aspartyl protease TAXi_C PF14541.6 KPA45203.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal G-patch PF01585.23 KPA45204.1 - 3.1e-12 46.2 2.3 5.6e-12 45.3 2.3 1.5 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 KPA45204.1 - 3.1e-08 32.8 1.1 8e-08 31.5 1.1 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 KPA45204.1 - 4.1e-06 26.8 1.8 4.1e-06 26.8 1.8 2.3 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 KPA45204.1 - 1.4e-05 24.8 0.1 0.013 15.3 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MT0933_antitox PF14013.6 KPA45204.1 - 0.00093 19.5 0.8 0.0031 17.8 0.1 2.3 2 0 0 2 2 2 1 MT0933-like antitoxin protein zf-C2H2_2 PF12756.7 KPA45204.1 - 0.0045 17.3 0.1 0.014 15.8 0.1 1.8 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) RED_N PF07808.13 KPA45204.1 - 0.007 16.0 1.7 0.007 16.0 1.7 2.9 3 0 0 3 3 3 1 RED-like protein N-terminal region MoaE PF02391.17 KPA45205.1 - 2.6e-36 124.3 0.0 3.3e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Ferric_reduct PF01794.19 KPA45207.1 - 4.4e-18 65.6 4.4 4.4e-18 65.6 4.4 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPA45207.1 - 9.7e-14 51.8 0.0 6.7e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPA45207.1 - 2.6e-12 46.8 0.0 6e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KPA45207.1 - 0.00025 21.7 0.0 0.12 13.0 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain AIM3 PF17096.5 KPA45207.1 - 0.15 13.0 1.5 0.37 11.8 1.5 1.6 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DUF4405 PF14358.6 KPA45207.1 - 0.56 10.8 7.4 0.2 12.2 0.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) RNase_PH PF01138.21 KPA45208.1 - 1e-20 74.6 0.0 1.9e-20 73.7 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KPA45208.1 - 0.00018 21.4 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 GDI PF00996.18 KPA45209.1 - 2.8e-25 88.7 0.0 5.8e-25 87.7 0.0 1.4 2 0 0 2 2 2 1 GDP dissociation inhibitor Rad21_Rec8_N PF04825.13 KPA45210.1 - 6.5e-34 116.4 0.0 1.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KPA45210.1 - 1e-05 24.7 0.0 2.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Imm10 PF15588.6 KPA45210.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 10 MFS_1 PF07690.16 KPA45211.1 - 8.9e-22 77.5 41.0 3e-18 65.9 13.1 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily ATP-synt_C PF00137.21 KPA45213.1 - 2.2e-28 98.3 37.4 3.2e-17 62.6 14.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ELP6 PF09807.9 KPA45213.1 - 0.052 13.0 0.0 0.062 12.7 0.0 1.1 1 0 0 1 1 1 0 Elongation complex protein 6 DUF2686 PF10887.8 KPA45213.1 - 0.11 11.5 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) CNH PF00780.22 KPA45214.1 - 1.4e-77 261.0 0.0 5e-77 259.2 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KPA45214.1 - 1.1e-43 148.6 0.0 2e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KPA45214.1 - 6.6e-35 121.0 0.0 1.3e-34 120.1 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KPA45214.1 - 6.4e-16 58.2 0.1 1.2e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Abhydrolase_1 PF00561.20 KPA45215.1 - 1.2e-22 80.8 0.2 4.7e-22 78.9 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KPA45215.1 - 4.4e-21 74.2 0.1 8.5e-21 73.3 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.13 KPA45215.1 - 9.1e-05 22.2 0.0 0.07 12.8 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KPA45215.1 - 0.00022 20.6 0.0 0.022 14.1 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 RTA1 PF04479.13 KPA45216.1 - 1.5e-73 246.8 3.8 2.3e-73 246.2 3.8 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2937 PF11157.8 KPA45216.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Abhydrolase_3 PF07859.13 KPA45217.1 - 6.8e-52 176.4 0.0 8.6e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPA45217.1 - 8.9e-06 24.8 0.0 3.4e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KPA45217.1 - 0.0089 15.5 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 KPA45217.1 - 0.047 12.4 0.0 0.1 11.3 0.0 1.4 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KPA45217.1 - 0.061 12.9 0.0 0.42 10.2 0.0 2.3 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KPA45217.1 - 0.14 11.8 0.2 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Putative esterase CNH PF00780.22 KPA45218.1 - 2.7e-61 207.6 0.0 3.9e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KPA45218.1 - 1.3e-31 110.3 2.0 2e-31 109.6 2.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KPA45218.1 - 7.1e-10 39.1 0.0 4.6e-09 36.5 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 KPA45218.1 - 0.00051 19.9 0.0 0.69 9.8 0.0 2.6 2 0 0 2 2 2 2 PH domain PH PF00169.29 KPA45218.1 - 0.00074 20.0 0.0 0.021 15.3 0.0 3.0 2 0 0 2 2 2 1 PH domain MPC PF03650.13 KPA45219.1 - 1.2e-47 160.6 0.2 2.1e-47 159.8 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 KPA45219.1 - 0.041 13.9 0.3 0.067 13.2 0.3 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange DUF1097 PF06496.11 KPA45219.1 - 0.26 11.4 2.7 0.39 10.8 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) L51_S25_CI-B8 PF05047.16 KPA45220.1 - 1.1e-14 54.0 0.0 1.4e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PAM2 PF07145.15 KPA45221.1 - 0.022 14.4 0.1 0.12 12.1 0.1 2.3 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DUF1687 PF07955.11 KPA45222.1 - 5.7e-32 110.9 0.0 7.7e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Ribosomal_L14e PF01929.17 KPA45224.1 - 3.1e-30 104.5 2.5 4.7e-30 103.9 2.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KPA45224.1 - 0.0037 17.2 4.1 0.016 15.2 0.9 2.8 2 1 0 2 2 2 1 KOW motif DRY_EERY PF09750.9 KPA45224.1 - 0.041 14.2 1.3 0.063 13.6 1.3 1.3 1 0 0 1 1 1 0 Alternative splicing regulator NAC PF01849.18 KPA45225.1 - 2.4e-23 81.8 0.1 8.2e-23 80.1 0.0 1.9 2 0 0 2 2 2 1 NAC domain RNA_pol_3_Rpc31 PF11705.8 KPA45225.1 - 0.012 15.9 5.9 0.012 15.9 5.9 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.18 KPA45225.1 - 2.6 7.9 18.6 0.059 13.3 11.1 1.6 1 1 0 2 2 2 0 Myc amino-terminal region Cwf_Cwc_15 PF04889.12 KPA45225.1 - 4.1 7.1 22.5 3 7.5 13.3 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GEMIN8 PF15348.6 KPA45225.1 - 5.8 7.2 12.1 0.14 12.5 2.3 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Mt_ATP-synt_D PF05873.12 KPA45226.1 - 4.9e-21 75.2 3.4 5.8e-21 75.0 3.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T5orf172 PF10544.9 KPA45226.1 - 0.066 13.8 0.2 0.24 11.9 0.2 1.9 1 1 0 1 1 1 0 T5orf172 domain Dor1 PF04124.12 KPA45226.1 - 0.095 11.4 3.0 0.12 11.1 2.6 1.3 1 1 0 1 1 1 0 Dor1-like family TPR_MLP1_2 PF07926.12 KPA45226.1 - 0.33 11.0 9.4 2.3 8.3 0.7 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2408 PF10303.9 KPA45226.1 - 0.64 10.6 4.8 5.1 7.7 4.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Abhydrolase_3 PF07859.13 KPA45227.1 - 7.2e-29 101.1 0.0 9.7e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-CHCC PF10276.9 KPA45227.1 - 0.079 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger domain Hydrolase_4 PF12146.8 KPA45227.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UQ_con PF00179.26 KPA45228.1 - 1.2e-47 161.1 0.0 1.3e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPA45228.1 - 0.00035 20.3 0.0 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KPA45228.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KPA45228.1 - 0.078 13.3 0.0 0.097 13.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 KPA45229.1 - 3.1e-07 31.0 16.2 0.015 16.2 0.2 5.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KPA45229.1 - 6e-07 29.0 10.5 1.3e-06 27.9 10.5 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 KPA45229.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 RWD domain zf-RING_9 PF13901.6 KPA45229.1 - 0.8 9.7 5.4 1.6 8.6 5.4 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon RAP1 PF07218.11 KPA45229.1 - 7.6 4.7 4.7 38 2.3 5.7 1.6 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) SOAR PF16533.5 KPA45230.1 - 0.12 12.3 0.0 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 STIM1 Orai1-activating region GPI2 PF06432.11 KPA45231.1 - 7.9e-135 448.7 0.2 9.5e-135 448.5 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase CFEM PF05730.11 KPA45232.1 - 1.2e-12 47.7 11.0 1.7e-12 47.3 11.0 1.2 1 0 0 1 1 1 1 CFEM domain DUF2291 PF10054.9 KPA45232.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) Metallophos_2 PF12850.7 KPA45233.1 - 4.5e-06 27.0 0.0 7.4e-05 23.0 0.0 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KPA45233.1 - 1.9e-05 25.3 0.0 3.8e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Med31 PF05669.12 KPA45234.1 - 1e-37 128.0 1.7 1.2e-37 127.7 1.7 1.1 1 0 0 1 1 1 1 SOH1 TFIIS_C PF01096.18 KPA45235.1 - 4e-20 71.4 1.7 4e-20 71.4 1.7 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KPA45235.1 - 3.4e-07 30.0 0.6 5.3e-06 26.2 0.1 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KPA45235.1 - 0.00028 20.8 6.1 0.017 15.1 0.8 2.4 2 1 0 2 2 2 2 Transposase zinc-ribbon domain Elf1 PF05129.13 KPA45235.1 - 0.0034 17.4 1.5 0.6 10.2 0.1 2.3 2 0 0 2 2 2 2 Transcription elongation factor Elf1 like Zn_ribbon_recom PF13408.6 KPA45235.1 - 0.0083 16.6 0.7 0.18 12.3 0.1 2.4 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Desulfoferrod_N PF06397.12 KPA45235.1 - 0.072 12.7 0.2 5.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain OrfB_Zn_ribbon PF07282.11 KPA45235.1 - 0.4 10.6 5.2 3.7 7.6 0.8 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 KPA45235.1 - 0.62 10.0 3.8 3.9 7.4 0.9 2.1 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn_ribbon_SprT PF17283.2 KPA45235.1 - 1.1 9.2 5.8 0.39 10.7 1.7 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Nudix_N_2 PF14803.6 KPA45235.1 - 4.3 7.3 7.9 5.3 7.1 2.9 2.7 2 1 0 2 2 2 0 Nudix N-terminal zinc_ribbon_4 PF13717.6 KPA45235.1 - 6.5 6.8 11.0 3 7.8 0.3 3.2 3 1 1 4 4 4 0 zinc-ribbon domain Ank_3 PF13606.6 KPA45236.1 - 6e-10 38.5 0.1 0.03 14.8 0.0 4.0 4 1 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KPA45236.1 - 3.1e-06 27.6 1.6 0.0047 17.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA45236.1 - 1.3e-05 25.7 0.0 4.9e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA45236.1 - 3.9e-05 23.9 0.1 1.8 9.0 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KPA45236.1 - 0.029 14.8 0.0 18 6.0 0.0 3.2 4 0 0 4 4 4 0 Ankyrin repeat Thaumatin PF00314.17 KPA45237.1 - 3.9e-68 229.3 9.1 4.9e-68 229.0 9.1 1.1 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KPA45237.1 - 0.0098 15.2 0.2 0.19 11.0 0.0 2.3 2 0 0 2 2 2 1 Beta-1,3-glucanase HSP70 PF00012.20 KPA45238.1 - 5.9e-11 41.3 0.3 1.7e-09 36.4 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KPA45238.1 - 0.033 13.0 0.1 0.18 10.6 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein FGGY_C PF02782.16 KPA45239.1 - 1.5e-70 237.0 1.6 4.5e-70 235.4 1.3 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KPA45239.1 - 1.1e-64 218.4 0.0 1.5e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BssC_TutF PF08201.11 KPA45239.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 BssC/TutF protein His_Phos_1 PF00300.22 KPA45241.1 - 3.8e-21 75.7 0.1 1.4e-20 73.8 0.0 1.7 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) VHS PF00790.19 KPA45242.1 - 2e-40 137.9 2.7 2.7e-40 137.5 0.0 2.1 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KPA45242.1 - 7.1e-15 54.9 4.5 1.2e-14 54.1 4.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KPA45242.1 - 6.5e-05 22.6 16.6 0.0025 17.6 1.5 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 KPA45242.1 - 0.00012 22.4 0.0 0.00031 21.0 0.0 1.8 1 0 0 1 1 1 1 GAT domain Ribosomal_S30AE PF02482.19 KPA45242.1 - 0.087 13.6 0.0 0.56 11.0 0.3 2.2 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein FYVE_2 PF02318.16 KPA45242.1 - 0.16 12.2 2.6 0.36 11.1 2.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger BAF1_ABF1 PF04684.13 KPA45242.1 - 0.16 11.0 3.4 0.28 10.2 3.4 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor C1_1 PF00130.22 KPA45242.1 - 0.24 11.3 6.1 0.47 10.4 6.1 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Fer4_2 PF12797.7 KPA45242.1 - 3.6 7.9 7.1 14 6.1 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain UCH PF00443.29 KPA45243.1 - 2e-36 125.8 0.0 3.3e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPA45243.1 - 5e-11 42.7 0.1 4.3e-10 39.7 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KPA45243.1 - 2.1e-08 34.6 0.0 4.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain AMP-binding PF00501.28 KPA45244.1 - 7.1e-83 278.5 0.0 1.2e-82 277.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PAN_3 PF08277.12 KPA45244.1 - 0.0022 17.8 0.2 0.0056 16.5 0.2 1.7 1 0 0 1 1 1 1 PAN-like domain AMP-binding_C PF13193.6 KPA45244.1 - 0.016 16.2 0.1 0.051 14.6 0.1 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_C PF12806.7 KPA45244.1 - 0.13 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like DUF4200 PF13863.6 KPA45244.1 - 1.1 9.7 5.4 0.35 11.3 2.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Med17 PF10156.9 KPA45245.1 - 7.2e-88 295.3 0.0 1e-87 294.8 0.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex SNF2_N PF00176.23 KPA45246.1 - 5.9e-47 160.1 0.3 9.4e-47 159.4 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA45246.1 - 1.8e-15 57.2 0.1 5.2e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KPA45246.1 - 6.5e-07 29.1 6.1 1.5e-06 27.9 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA45246.1 - 3.7e-06 26.7 7.4 8.1e-06 25.6 4.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA45246.1 - 8.2e-06 25.6 7.9 2.1e-05 24.3 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA45246.1 - 0.00024 21.0 3.4 0.00024 21.0 3.4 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KPA45246.1 - 0.00043 20.6 8.5 0.00043 20.6 8.5 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KPA45246.1 - 0.0029 17.7 8.1 0.012 15.7 8.2 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING ERCC3_RAD25_C PF16203.5 KPA45246.1 - 0.003 16.8 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SPT6_acidic PF14632.6 KPA45246.1 - 0.0098 16.5 5.1 0.0098 16.5 5.1 2.3 2 0 0 2 2 2 1 Acidic N-terminal SPT6 zf-RING_4 PF14570.6 KPA45246.1 - 0.11 12.3 6.2 0.8 9.6 6.7 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Pellino PF04710.14 KPA45246.1 - 0.15 10.7 1.2 0.24 10.0 1.2 1.3 1 0 0 1 1 1 0 Pellino CDC45 PF02724.14 KPA45246.1 - 0.17 10.1 3.7 0.11 10.8 2.1 1.4 2 0 0 2 2 2 0 CDC45-like protein zf-MIZ PF02891.20 KPA45246.1 - 0.18 11.6 4.6 0.51 10.1 4.6 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Rad50_zn_hook PF04423.14 KPA45246.1 - 0.37 10.6 2.7 1.2 9.0 0.9 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_5 PF14634.6 KPA45246.1 - 1.4 9.0 14.8 0.031 14.2 7.8 2.0 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KPA45246.1 - 5.6 6.9 14.3 2.3e+02 1.7 14.8 2.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SOG2 PF10428.9 KPA45247.1 - 4.1e-76 257.2 0.0 1.4e-51 176.3 0.1 3.9 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 KPA45247.1 - 4.6e-14 51.9 1.2 1.3e-05 24.8 0.1 3.1 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KPA45247.1 - 1.6e-12 47.4 10.7 7.8e-06 26.1 0.4 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KPA45247.1 - 0.0019 18.1 2.5 0.58 10.4 0.0 4.2 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 KPA45247.1 - 0.0023 18.2 3.8 11 7.0 0.1 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat DUF2408 PF10303.9 KPA45247.1 - 0.0029 18.2 0.0 0.0061 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) GCN5L1 PF06320.13 KPA45248.1 - 8.4e-16 58.1 3.4 1.3e-15 57.6 3.4 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF1387 PF07139.11 KPA45248.1 - 0.00033 20.5 1.1 0.00046 20.0 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) Rootletin PF15035.6 KPA45248.1 - 0.0025 17.9 0.3 0.0036 17.3 0.3 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.6 KPA45248.1 - 0.022 14.6 1.8 0.031 14.1 1.8 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Bap31_Bap29_C PF18035.1 KPA45248.1 - 0.032 14.2 0.8 0.056 13.5 0.8 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2968 PF11180.8 KPA45248.1 - 0.16 11.6 6.3 0.27 10.8 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) SPX PF03105.19 KPA45248.1 - 0.21 11.5 4.7 0.27 11.1 4.7 1.1 1 0 0 1 1 1 0 SPX domain TMF_TATA_bd PF12325.8 KPA45248.1 - 0.22 11.7 2.2 0.37 11.0 2.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF737 PF05300.11 KPA45248.1 - 1.7 8.9 6.3 2.8 8.3 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Steroid_dh PF02544.16 KPA45249.1 - 2.7e-28 98.8 1.2 2.7e-28 98.8 1.2 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KPA45249.1 - 6.4e-05 22.6 2.5 8.9e-05 22.1 0.6 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ubiquitin PF00240.23 KPA45249.1 - 0.027 14.2 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Ribosomal_S8e PF01201.22 KPA45250.1 - 4.3e-52 175.9 2.5 4.3e-52 175.9 2.5 2.0 2 0 0 2 2 2 1 Ribosomal protein S8e TIP_N PF12457.8 KPA45250.1 - 0.041 14.2 0.4 0.041 14.2 0.4 2.9 3 0 0 3 3 3 0 Tuftelin interacting protein N terminal SMAP PF15477.6 KPA45250.1 - 5.3 8.1 9.1 1.1 10.3 1.0 3.5 2 1 1 3 3 3 0 Small acidic protein family RabGAP-TBC PF00566.18 KPA45251.1 - 2.4e-48 164.6 0.2 2.4e-48 164.6 0.2 3.0 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 KPA45251.1 - 0.00018 21.6 6.5 0.00018 21.6 6.5 4.4 3 1 1 4 4 4 2 Centrosomin N-terminal motif 1 YabA PF06156.13 KPA45251.1 - 0.025 15.2 2.8 0.025 15.2 2.8 4.5 3 2 1 4 4 4 0 Initiation control protein YabA DUF908 PF06012.12 KPA45252.1 - 2.1e-132 441.9 0.7 2.1e-132 441.9 0.7 4.0 6 0 0 6 6 6 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 KPA45252.1 - 5.6e-132 440.2 0.0 5.6e-132 440.2 0.0 6.0 7 1 0 7 7 7 2 Domain of Unknown Function (DUF913) HECT PF00632.25 KPA45252.1 - 3.4e-92 309.2 0.1 6.1e-92 308.4 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KPA45252.1 - 9.6e-24 82.1 24.2 4.9e-09 35.3 1.6 4.2 4 0 0 4 4 4 3 Ubiquitin binding region Ribosomal_S6e PF01092.19 KPA45253.1 - 1.2e-58 196.5 0.0 2.4e-58 195.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e VRP1 PF03538.14 KPA45253.1 - 0.24 10.8 2.1 0.31 10.4 2.1 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein Ctf8 PF09696.10 KPA45254.1 - 5.5e-42 143.5 1.3 4.4e-41 140.6 1.3 1.9 1 1 0 1 1 1 1 Ctf8 Diphthamide_syn PF01866.17 KPA45255.1 - 1.2e-116 389.4 0.0 1.5e-116 389.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein ATP-synt_ab PF00006.25 KPA45256.1 - 3.1e-66 223.1 0.0 5.7e-66 222.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KPA45256.1 - 3.1e-14 53.2 0.7 6.2e-14 52.3 0.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 KPA45256.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5535) HMGL-like PF00682.19 KPA45257.1 - 1.4e-43 149.4 0.0 1.6e-42 145.9 0.0 2.0 1 1 0 1 1 1 1 HMGL-like Tubulin PF00091.25 KPA45258.1 - 4.2e-66 222.9 0.0 6.1e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KPA45258.1 - 1.7e-49 167.2 0.1 3e-49 166.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KPA45258.1 - 0.0034 17.1 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.9 KPA45259.1 - 0.00033 20.5 0.0 0.00077 19.4 0.0 1.6 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Pur_ac_phosph_N PF16656.5 KPA45259.1 - 0.011 16.3 0.0 0.022 15.3 0.0 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain DUF4365 PF14280.6 KPA45259.1 - 0.037 14.0 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4365) WW PF00397.26 KPA45260.1 - 1.2e-10 41.3 0.5 2.5e-10 40.3 0.5 1.6 1 0 0 1 1 1 1 WW domain Mo-co_dimer PF03404.16 KPA45261.1 - 0.041 13.9 0.1 0.064 13.3 0.1 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain LsmAD PF06741.13 KPA45262.1 - 3e-27 95.0 1.5 3e-27 95.0 1.5 2.6 3 0 0 3 3 3 1 LsmAD domain Peptidase_M16 PF00675.20 KPA45263.1 - 6.1e-15 55.5 0.2 1.1e-14 54.6 0.2 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KPA45263.1 - 3.4e-10 40.2 0.0 5.6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.13 KPA45264.1 - 8.2e-51 173.2 0.0 3.4e-49 167.9 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KPA45264.1 - 4e-14 52.4 1.2 4.2e-12 46.0 0.1 3.0 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KPA45264.1 - 0.00016 21.5 0.3 0.032 14.1 0.0 3.4 2 1 1 3 3 3 1 TFIIE alpha subunit Mito_carr PF00153.27 KPA45265.1 - 2.4e-29 101.1 0.4 1.2e-14 54.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Apolipoprotein PF01442.18 KPA45266.1 - 0.0023 17.9 6.8 0.0023 17.9 6.8 12.5 4 2 5 9 9 9 1 Apolipoprotein A1/A4/E domain CENP-F_leu_zip PF10473.9 KPA45266.1 - 0.0026 17.8 13.5 0.0026 17.8 13.5 11.7 7 3 4 13 13 13 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3849 PF12960.7 KPA45266.1 - 0.093 12.7 3.7 0.37 10.8 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3849) MIF4G PF02854.19 KPA45266.1 - 0.11 12.2 2.6 3.8 7.1 0.1 3.3 2 0 0 2 2 2 0 MIF4G domain Tup_N PF08581.10 KPA45266.1 - 0.18 12.1 29.0 0.74 10.2 0.2 10.3 9 2 3 12 12 12 0 Tup N-terminal DUF3427 PF11907.8 KPA45266.1 - 0.98 8.6 16.2 0.04 13.2 5.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3427) HALZ PF02183.18 KPA45266.1 - 4.3 7.7 25.3 14 6.0 0.0 9.9 12 0 0 12 12 12 0 Homeobox associated leucine zipper DUF2524 PF10732.9 KPA45266.1 - 4.4 7.7 20.5 0.11 12.8 0.2 7.2 7 0 0 7 7 7 0 Protein of unknown function (DUF2524) MCC-bdg_PDZ PF10506.9 KPA45266.1 - 8.9 6.4 8.2 2.3 8.3 0.1 4.6 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DASH_Dad3 PF08656.10 KPA45267.1 - 3.4e-33 113.5 0.4 3.9e-33 113.4 0.4 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 MetOD2 PF18548.1 KPA45267.1 - 0.091 12.9 0.2 0.16 12.1 0.2 1.3 1 0 0 1 1 1 0 Metanogen output domain 2 DASH_Dam1 PF08653.10 KPA45267.1 - 0.17 11.7 0.7 0.63 9.9 0.4 1.9 1 1 1 2 2 2 0 DASH complex subunit Dam1 Ribosomal_S5_C PF03719.15 KPA45268.1 - 1.5e-22 78.8 0.0 1.2e-21 75.9 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KPA45268.1 - 2.9e-17 62.4 0.2 5.7e-17 61.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF5446 PF17522.2 KPA45268.1 - 0.13 12.4 0.9 0.32 11.2 0.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF4951 PF16309.5 KPA45268.1 - 0.15 12.1 0.1 0.54 10.3 0.1 1.9 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) SHR3_chaperone PF08229.11 KPA45269.1 - 0.011 14.7 0.1 0.011 14.7 0.1 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 OAD_gamma PF04277.13 KPA45269.1 - 0.02 15.5 0.5 0.034 14.8 0.5 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PspB PF06667.12 KPA45269.1 - 0.042 13.9 0.1 0.053 13.6 0.1 1.1 1 0 0 1 1 1 0 Phage shock protein B TssO PF17561.2 KPA45269.1 - 0.082 13.0 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF4834 PF16118.5 KPA45269.1 - 0.16 12.9 0.0 0.19 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 KPA45269.1 - 0.24 11.7 1.6 0.34 11.2 1.5 1.4 1 1 0 1 1 1 0 Orf78 (ac78) Renin_r PF07850.14 KPA45269.1 - 1.8 9.2 5.0 0.73 10.5 2.2 1.6 1 1 1 2 2 2 0 Renin receptor-like protein SIT PF15330.6 KPA45269.1 - 2.9 8.4 4.7 5.6 7.5 4.7 1.5 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT FAM165 PF14981.6 KPA45269.1 - 7.2 6.5 8.3 17 5.3 8.3 1.7 1 1 0 1 1 1 0 FAM165 family RasGEF PF00617.19 KPA45271.1 - 1.3e-44 152.5 0.2 3.1e-44 151.3 0.2 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KPA45271.1 - 1.4e-12 47.8 0.6 2.8e-12 46.8 0.1 1.8 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 KPA45271.1 - 0.00087 18.9 0.4 0.006 16.2 0.1 2.4 2 1 0 2 2 2 1 Ras family RsgA_GTPase PF03193.16 KPA45271.1 - 0.0041 17.0 0.1 0.52 10.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KPA45271.1 - 0.015 15.5 0.0 0.12 12.5 0.0 2.5 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KPA45271.1 - 0.087 12.9 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 KPA45271.1 - 0.21 11.7 0.3 0.49 10.4 0.3 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain IIGP PF05049.13 KPA45271.1 - 0.66 9.0 3.2 0.47 9.5 0.1 2.1 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) PROL5-SMR PF15621.6 KPA45271.1 - 2.6 8.6 4.8 1.8 9.1 0.2 2.5 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family zf-HIT PF04438.16 KPA45273.1 - 4.5e-10 39.2 12.0 6.2e-10 38.8 12.0 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KPA45273.1 - 2.1e-05 24.5 5.2 3.2e-05 23.9 5.2 1.3 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.24 KPA45273.1 - 0.062 13.5 4.6 0.089 13.0 4.6 1.2 1 0 0 1 1 1 0 B-box zinc finger Nfu_N PF08712.11 KPA45274.1 - 2.3e-29 101.2 0.1 1.6e-28 98.6 0.0 2.1 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KPA45274.1 - 1e-26 92.8 0.0 1.9e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 KPA45274.1 - 0.00091 19.3 0.8 0.0031 17.6 0.8 1.8 2 0 0 2 2 2 1 Bacterial membrane-spanning protein N-terminus ADH_N PF08240.12 KPA45275.1 - 3.2e-28 97.8 2.4 7.5e-28 96.6 2.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA45275.1 - 2.2e-18 66.5 0.0 3.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPA45275.1 - 7e-06 25.7 1.6 0.00015 21.4 1.6 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 KPA45275.1 - 0.037 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KPA45275.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 KPA45275.1 - 0.14 12.8 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ATP-synt_G PF04718.15 KPA45276.1 - 2.7e-35 121.2 0.7 2.7e-35 121.2 0.7 1.8 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit CAP_N PF01213.19 KPA45276.1 - 0.04 13.4 0.0 0.048 13.2 0.0 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_23 PF13489.6 KPA45277.1 - 2.8e-18 66.3 0.0 4.6e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA45277.1 - 4.1e-05 24.2 0.0 0.00027 21.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA45277.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KPA45277.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KPA45277.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KPA45277.1 - 0.02 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 KPA45277.1 - 0.093 13.5 0.0 0.91 10.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KPA45277.1 - 0.17 11.2 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TFIIA PF03153.13 KPA45278.1 - 6.8e-91 306.3 51.3 3.5e-90 304.0 51.3 1.8 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.10 KPA45278.1 - 0.54 10.7 10.5 1.2 9.6 10.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Presenilin PF01080.17 KPA45278.1 - 0.99 8.1 15.5 1.7 7.3 15.5 1.3 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 KPA45278.1 - 1.8 7.6 16.3 2.4 7.3 16.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Neur_chan_memb PF02932.16 KPA45278.1 - 6.6 6.7 9.5 11 6.0 9.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Glyco_hydro_47 PF01532.20 KPA45279.1 - 2.2e-175 584.0 0.1 2.7e-175 583.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 KPA45279.1 - 0.015 14.4 0.3 0.13 11.3 0.2 2.2 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KPA45279.1 - 0.049 12.1 0.0 1.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 ANAPC4_WD40 PF12894.7 KPA45280.1 - 1.3e-17 63.9 4.4 3.8e-05 23.9 0.2 4.4 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPA45280.1 - 3.7e-17 62.4 21.2 0.00025 21.8 0.1 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KPA45280.1 - 3.6e-07 29.5 0.2 0.00025 20.1 0.0 3.7 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KPA45280.1 - 3.7e-07 30.2 0.1 0.00029 20.8 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Kelch_4 PF13418.6 KPA45281.1 - 1.3e-29 101.9 7.3 7.2e-09 35.5 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KPA45281.1 - 4.4e-24 84.0 2.0 3.8e-07 30.0 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KPA45281.1 - 1.6e-23 82.1 5.9 4.6e-05 23.6 0.0 5.1 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KPA45281.1 - 2.3e-22 78.3 2.0 2.5e-05 23.7 0.0 5.1 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KPA45281.1 - 4.2e-21 74.7 3.5 2.3e-07 30.9 0.1 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KPA45281.1 - 8.9e-20 69.8 2.8 0.00039 20.3 0.0 5.1 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 KPA45281.1 - 4.7e-09 36.5 0.0 7.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_aberr PF17017.5 KPA45282.1 - 3e-05 24.3 1.6 0.024 14.8 0.2 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KPA45282.1 - 7.5e-05 23.0 10.8 0.18 12.4 0.8 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA45282.1 - 0.00098 19.8 11.3 0.38 11.7 1.0 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPA45282.1 - 0.018 15.5 9.1 0.28 11.7 1.0 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Ribophorin_I PF04597.14 KPA45283.1 - 2.7e-150 501.4 0.3 3.3e-150 501.2 0.3 1.1 1 0 0 1 1 1 1 Ribophorin I Pil1 PF13805.6 KPA45284.1 - 7.6e-110 366.6 4.2 1e-109 366.2 4.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 APG6_N PF17675.1 KPA45284.1 - 1.6 9.2 7.1 1.5 9.3 5.2 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Pyrophosphatase PF00719.19 KPA45285.1 - 5.9e-59 198.4 0.1 1.1e-58 197.6 0.1 1.4 2 0 0 2 2 2 1 Inorganic pyrophosphatase MRP_L53 PF10780.9 KPA45286.1 - 8.8e-21 73.8 0.7 1.7e-20 72.9 0.7 1.5 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 KorB_C PF06613.11 KPA45286.1 - 0.038 14.0 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain Ecotin PF03974.13 KPA45286.1 - 0.082 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Ecotin Sec20 PF03908.13 KPA45287.1 - 2.7e-14 52.8 0.5 7.1e-14 51.5 0.1 2.0 2 0 0 2 2 2 1 Sec20 ArAE_2 PF10334.9 KPA45287.1 - 0.043 13.6 0.2 0.093 12.6 0.2 1.6 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 FAM76 PF16046.5 KPA45287.1 - 0.22 10.9 5.2 0.32 10.3 5.2 1.2 1 0 0 1 1 1 0 FAM76 protein Seryl_tRNA_N PF02403.22 KPA45287.1 - 1.6 9.0 5.3 3.5 7.9 0.4 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain UPF0242 PF06785.11 KPA45287.1 - 9.9 6.2 19.4 1.8 8.6 3.6 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Aldolase_II PF00596.21 KPA45288.1 - 2.6e-43 148.1 0.0 3.1e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain VDE PF07137.11 KPA45289.1 - 1.1 8.7 8.3 2.1 7.8 8.2 1.6 1 1 0 1 1 1 0 VDE lipocalin domain MGC-24 PF05283.11 KPA45289.1 - 2.4 8.6 20.1 0.028 14.9 10.4 2.1 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Calreticulin PF00262.18 KPA45290.1 - 2.6e-167 556.3 20.1 3.8e-167 555.7 20.1 1.2 1 0 0 1 1 1 1 Calreticulin family Aldedh PF00171.22 KPA45291.1 - 1.3e-135 452.5 1.0 1.5e-135 452.3 1.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 KPA45291.1 - 0.085 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family FAD_binding_3 PF01494.19 KPA45292.1 - 1.6e-74 251.2 0.0 2.1e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KPA45292.1 - 1.6e-30 106.3 0.0 2.9e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KPA45292.1 - 1.9e-05 24.0 0.0 3.7e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPA45292.1 - 7.7e-05 21.6 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KPA45292.1 - 0.00014 22.0 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPA45292.1 - 0.00091 18.4 0.1 0.002 17.2 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 KPA45292.1 - 0.0016 19.0 0.0 0.0038 17.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA45292.1 - 0.0063 16.1 0.1 0.022 14.4 0.1 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KPA45292.1 - 0.025 13.5 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KPA45292.1 - 0.033 13.5 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KPA45292.1 - 0.045 13.0 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPA45292.1 - 0.051 12.6 0.0 0.093 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KPA45292.1 - 0.098 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KPA45292.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KPA45292.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KPA45292.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 KPA45292.1 - 0.17 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding adh_short PF00106.25 KPA45293.1 - 1.1e-37 129.4 0.1 1.6e-37 128.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA45293.1 - 5.8e-29 101.3 0.0 8.1e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA45293.1 - 2.4e-10 40.6 2.1 3.9e-09 36.7 2.1 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA45293.1 - 2.1e-07 30.6 0.1 5e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA45293.1 - 0.00081 18.5 0.1 0.0014 17.7 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KPA45293.1 - 0.0028 16.8 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 KPA45293.1 - 0.0036 16.7 0.0 0.0071 15.7 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KPA45293.1 - 0.0065 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KPA45293.1 - 0.046 13.6 0.9 0.26 11.1 0.9 2.1 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KPA45293.1 - 0.1 13.2 0.2 0.28 11.8 0.2 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Indigoidine_A PF04227.12 KPA45295.1 - 6e-107 357.3 1.1 8.9e-107 356.8 1.1 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KPA45295.1 - 2.9e-22 79.3 0.1 2.9e-12 46.5 0.0 2.9 3 0 0 3 3 3 2 pfkB family carbohydrate kinase WD40 PF00400.32 KPA45296.1 - 4.4e-07 30.5 0.1 3.7 8.6 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA45296.1 - 3.2e-06 27.3 0.0 0.54 10.6 0.0 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KPA45296.1 - 0.056 13.4 0.0 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat SLD5_C PF16922.5 KPA45299.1 - 1.2e-12 47.8 0.0 2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KPA45299.1 - 7.4e-08 32.8 0.3 2.4e-07 31.2 0.1 1.9 2 0 0 2 2 2 1 GINS complex protein DUF896 PF05979.12 KPA45299.1 - 0.029 14.2 0.1 0.098 12.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) TetR_C_7 PF14246.6 KPA45299.1 - 0.03 14.4 0.2 1.3 9.0 0.1 2.2 1 1 1 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Far-17a_AIG1 PF04750.14 KPA45300.1 - 7.1e-46 156.1 14.3 8.1e-46 155.9 14.3 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pro_isomerase PF00160.21 KPA45301.1 - 2.3e-51 174.2 0.2 5.6e-51 172.9 0.2 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KPA45301.1 - 6.2e-09 36.3 0.2 0.0091 16.8 0.0 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA45301.1 - 3e-05 24.2 0.0 0.014 15.6 0.0 3.9 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA45301.1 - 0.046 12.7 0.2 5.7 5.8 0.1 2.5 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MFS_1 PF07690.16 KPA45302.1 - 1e-34 120.0 26.6 2.9e-34 118.6 27.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TMEM190 PF15431.6 KPA45302.1 - 0.03 14.5 0.1 3.5 7.8 0.0 2.7 2 0 0 2 2 2 0 Transmembrane protein 190 MASE2 PF05230.11 KPA45302.1 - 0.082 13.0 7.1 1.2 9.2 0.8 2.9 2 1 0 2 2 2 0 MASE2 domain LapA_dom PF06305.11 KPA45302.1 - 0.61 10.0 9.9 14 5.6 1.5 4.4 4 1 1 5 5 5 0 Lipopolysaccharide assembly protein A domain Steroid_dh PF02544.16 KPA45303.1 - 9.3e-20 71.1 0.4 3.7e-13 49.7 0.1 2.3 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KPA45303.1 - 0.02 14.4 3.4 0.039 13.5 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) CHD5 PF04420.14 KPA45303.1 - 0.28 11.0 1.4 0.62 9.9 1.4 1.5 1 0 0 1 1 1 0 CHD5-like protein MINDY_DUB PF04424.13 KPA45304.1 - 2.7e-25 88.7 0.0 4e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase DUF1977 PF09320.11 KPA45305.1 - 1.1e-27 96.4 0.2 2.6e-27 95.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KPA45305.1 - 2e-19 69.4 0.1 3.5e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Coprogen_oxidas PF01218.18 KPA45305.1 - 0.0069 15.1 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase ODV-E18 PF10717.9 KPA45305.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Cellulase PF00150.18 KPA45306.1 - 6.7e-54 183.2 5.2 8.2e-54 182.9 5.2 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5103 PF17116.5 KPA45306.1 - 0.04 13.2 0.3 0.057 12.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5103) Ribosomal_S19 PF00203.21 KPA45307.1 - 1.7e-27 95.1 0.0 2e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.13 KPA45308.1 - 2.9e-26 91.2 0.3 5e-26 90.4 0.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TAF4 PF05236.14 KPA45308.1 - 0.082 12.6 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family ER_lumen_recept PF00810.18 KPA45309.1 - 2.5e-54 184.1 8.1 2.5e-54 184.1 8.1 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor COX7B PF05392.11 KPA45309.1 - 0.37 10.5 1.6 0.57 9.9 0.1 1.9 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB PQ-loop PF04193.14 KPA45309.1 - 2 8.3 13.2 1.3 8.8 0.4 3.6 3 1 1 4 4 4 0 PQ loop repeat Nop14 PF04147.12 KPA45310.1 - 0.33 9.1 14.9 0.44 8.7 14.9 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 KPA45310.1 - 8.4 5.7 14.7 16 4.8 14.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Histone PF00125.24 KPA45311.1 - 6.1e-18 65.4 0.0 7.7e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KPA45311.1 - 1.6e-13 50.2 0.1 3.4e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KPA45311.1 - 3.5e-05 24.0 0.0 5.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 KPA45311.1 - 0.05 13.7 0.1 0.067 13.3 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region R3H PF01424.22 KPA45312.1 - 9.9e-11 41.5 0.2 1.9e-10 40.6 0.2 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KPA45312.1 - 2.7e-05 23.9 0.0 6.7e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF357 PF04010.13 KPA45312.1 - 0.17 12.0 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF357) ADH_zinc_N PF00107.26 KPA45313.1 - 3.4e-24 85.3 0.1 5.3e-24 84.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA45313.1 - 2.5e-19 70.6 0.0 5.2e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPA45313.1 - 1.8e-05 24.6 0.0 4.5e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_N PF08240.12 KPA45313.1 - 4.1e-05 23.4 0.2 0.0001 22.1 0.2 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PAP2_3 PF14378.6 KPA45314.1 - 3.3e-38 131.3 9.2 5.2e-38 130.6 9.2 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 KPA45314.1 - 0.00014 21.7 6.8 0.00019 21.2 5.8 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KPA45314.1 - 0.025 15.1 0.4 0.025 15.1 0.4 2.8 3 0 0 3 3 3 0 PAP2 superfamily C-terminal ELYS PF13934.6 KPA45315.1 - 0.0025 17.8 0.1 0.0077 16.2 0.0 1.9 2 0 0 2 2 2 1 Nuclear pore complex assembly Abi_C PF14355.6 KPA45315.1 - 0.064 13.4 1.1 0.56 10.3 0.1 3.0 2 0 0 2 2 2 0 Abortive infection C-terminus DUF3367 PF11847.8 KPA45315.1 - 0.22 9.3 1.2 0.39 8.5 1.2 1.3 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase BC10 PF06726.12 KPA45316.1 - 3.4e-18 65.6 11.3 3.4e-18 65.6 11.3 1.7 2 0 0 2 2 2 1 Bladder cancer-related protein BC10 F-box PF00646.33 KPA45318.1 - 0.003 17.4 4.5 0.0048 16.7 0.9 2.4 2 0 0 2 2 2 1 F-box domain TMEM89 PF15098.6 KPA45319.1 - 0.00021 21.5 0.4 0.00021 21.5 0.4 2.1 3 0 0 3 3 3 1 TMEM89 protein family Podoplanin PF05808.11 KPA45319.1 - 0.099 12.7 3.3 0.18 11.9 2.1 2.1 1 1 0 1 1 1 0 Podoplanin CytochromB561_N PF09786.9 KPA45319.1 - 2.2 7.2 7.2 22 3.8 7.2 2.0 1 1 0 1 1 1 0 Cytochrome B561, N terminal Fungal_trans_2 PF11951.8 KPA45320.1 - 2.1e-58 198.0 0.5 4.7e-58 196.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA45320.1 - 1.8e-07 31.2 12.2 3.2e-07 30.3 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA45321.1 - 1.9e-24 86.1 0.0 3.7e-22 78.6 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA45321.1 - 1.3e-08 34.8 9.4 2.2e-08 34.1 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH_1 PF00378.20 KPA45322.1 - 1.1e-18 67.4 0.0 1.4e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA45322.1 - 4.5e-08 33.0 0.0 5.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glycos_transf_1 PF00534.20 KPA45323.1 - 1.1e-33 116.3 0.0 8.5e-32 110.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KPA45323.1 - 3.2e-15 56.5 0.4 4.9e-15 55.9 0.4 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KPA45323.1 - 1.6e-14 54.5 0.0 4.4e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KPA45323.1 - 8.5e-07 29.5 0.7 8.5e-07 29.5 0.7 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 KPA45323.1 - 0.00032 20.8 0.3 0.74 9.8 0.1 2.8 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glyco_trans_1_2 PF13524.6 KPA45323.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Pkinase PF00069.25 KPA45324.1 - 5.5e-50 170.2 0.1 9e-34 117.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA45324.1 - 9.3e-22 77.5 0.2 5.3e-20 71.8 0.1 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA45324.1 - 0.00023 20.6 0.0 0.00092 18.6 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KPA45324.1 - 0.007 16.3 0.1 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family BPL_LplA_LipB PF03099.19 KPA45325.1 - 1.4e-05 25.1 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.21 KPA45326.1 - 3.3e-140 466.5 0.0 3.7e-140 466.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase RHH_3 PF12651.7 KPA45326.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Ribbon-helix-helix domain RabGAP-TBC PF00566.18 KPA45327.1 - 4.4e-48 163.8 0.0 7.5e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NAM-associated PF14303.6 KPA45327.1 - 0.037 14.7 0.0 0.8 10.4 0.0 3.1 3 1 0 3 3 3 0 No apical meristem-associated C-terminal domain Filament PF00038.21 KPA45327.1 - 1 8.9 6.6 0.13 11.9 0.6 2.1 2 0 0 2 2 2 0 Intermediate filament protein LRR_4 PF12799.7 KPA45328.1 - 1.6e-28 98.3 26.9 1e-05 25.8 3.1 8.6 4 1 5 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPA45328.1 - 1.3e-15 56.9 27.6 0.00034 20.3 2.9 7.1 4 2 5 9 9 9 6 Leucine rich repeat LRR_9 PF14580.6 KPA45328.1 - 3.8e-09 36.3 10.5 0.002 17.6 0.8 4.6 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 KPA45328.1 - 0.0013 18.6 17.3 4.4 7.6 0.0 7.0 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 KPA45328.1 - 0.15 12.7 12.7 91 4.2 0.2 8.1 7 2 0 7 7 7 0 Leucine Rich Repeat FMO-like PF00743.19 KPA45330.1 - 8e-41 140.0 0.0 4.7e-23 81.4 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPA45330.1 - 1.2e-14 54.3 1.0 1.4e-06 27.8 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA45330.1 - 5.3e-13 48.9 0.0 3.7e-12 46.1 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA45330.1 - 5.8e-11 42.1 0.0 6.3e-09 35.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KPA45330.1 - 9.4e-11 41.9 0.0 0.00032 20.4 0.0 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPA45330.1 - 5e-10 39.6 0.0 1.4e-06 28.4 0.0 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPA45330.1 - 5.5e-08 32.9 0.0 4e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPA45330.1 - 3.4e-07 29.8 0.0 0.0011 18.2 0.1 2.4 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 KPA45330.1 - 1.5e-05 23.9 0.0 0.033 12.9 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein Shikimate_DH PF01488.20 KPA45330.1 - 4.4e-05 23.6 0.0 0.002 18.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KPA45330.1 - 4.7e-05 23.9 0.0 0.25 11.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPA45330.1 - 0.0007 19.0 0.0 0.0096 15.2 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KPA45330.1 - 0.0013 18.0 0.0 0.043 13.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Glu_dehyd_C PF16912.5 KPA45330.1 - 0.012 15.1 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus FAD_oxidored PF12831.7 KPA45330.1 - 0.015 14.7 0.4 0.64 9.3 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase MCRA PF06100.11 KPA45330.1 - 0.053 12.3 1.2 0.056 12.2 0.2 1.4 2 0 0 2 2 2 0 MCRA family ThiF PF00899.21 KPA45330.1 - 0.075 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 ThiF family FAD_binding_2 PF00890.24 KPA45330.1 - 0.076 12.1 0.0 3.4 6.7 0.0 2.5 2 1 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.12 KPA45330.1 - 0.084 11.9 0.0 5.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein POT1 PF02765.17 KPA45331.1 - 4.4e-15 55.8 0.0 9.6e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Malic_M PF03949.15 KPA45332.1 - 1.9e-91 305.9 0.0 2.7e-91 305.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KPA45332.1 - 5.3e-70 234.9 0.0 8.8e-70 234.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Fungal_trans PF04082.18 KPA45333.1 - 3e-39 134.6 1.9 6.4e-39 133.6 0.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA45333.1 - 5.1e-08 32.9 9.6 9.5e-08 32.0 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GAS2 PF02187.17 KPA45334.1 - 7.7e-07 29.1 0.1 1.8e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain zf-C2H2_12 PF18658.1 KPA45334.1 - 0.49 10.0 4.0 12 5.6 0.6 2.8 3 0 0 3 3 3 0 Zinc-finger C2H2-type MMR_HSR1 PF01926.23 KPA45335.1 - 3e-17 62.7 0.1 3.8e-15 56.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA45335.1 - 4.4e-07 30.0 0.0 0.00053 19.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KPA45335.1 - 6.3e-07 29.1 0.3 2.3e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KPA45335.1 - 0.0046 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family TRAP_alpha PF03896.16 KPA45335.1 - 0.033 13.4 1.5 0.057 12.6 1.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Dynamin_N PF00350.23 KPA45335.1 - 0.32 11.0 11.3 0.24 11.4 1.0 3.2 3 1 1 4 4 4 0 Dynamin family Rep_4 PF05797.11 KPA45335.1 - 1.1 8.3 3.0 1.7 7.7 3.0 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) LTV PF04180.14 KPA45336.1 - 1.6e-129 433.0 21.8 1.8e-129 432.8 21.8 1.0 1 0 0 1 1 1 1 Low temperature viability protein SAC3_GANP PF03399.16 KPA45337.1 - 3.8e-94 315.3 0.1 7.2e-94 314.4 0.1 1.5 1 0 0 1 1 1 1 SAC3/GANP family CRR7 PF12095.8 KPA45337.1 - 0.075 13.5 0.5 6.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 NmrA PF05368.13 KPA45338.1 - 1.8e-85 286.2 0.0 2.7e-85 285.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA45338.1 - 3.2e-07 30.4 0.1 2.6e-06 27.5 0.1 2.0 1 1 0 1 1 1 1 NAD(P)H-binding DUF3798 PF12683.7 KPA45338.1 - 0.054 12.9 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Fungal_trans PF04082.18 KPA45339.1 - 2.6e-15 56.2 0.9 4.2e-15 55.5 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA45339.1 - 6.6e-08 32.5 12.6 1.1e-07 31.8 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fcf1 PF04900.12 KPA45340.1 - 4.2e-35 120.1 0.2 7.9e-35 119.2 0.2 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KPA45340.1 - 4.6e-14 52.7 0.4 2.3e-12 47.2 0.0 2.1 2 0 0 2 2 2 1 PIN like domain GCV_T PF01571.21 KPA45340.1 - 0.084 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Rep_fac_C PF08542.11 KPA45341.1 - 1.8e-22 79.5 0.0 4.8e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KPA45341.1 - 8.1e-12 45.2 0.0 9.9e-09 35.2 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KPA45341.1 - 1.9e-11 44.5 0.0 3.4e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KPA45341.1 - 6.4e-07 29.5 0.0 1.3e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA45341.1 - 3.3e-06 27.6 0.1 0.00022 21.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KPA45341.1 - 2.6e-05 24.0 0.0 6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KPA45341.1 - 6.6e-05 23.2 0.1 0.045 14.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KPA45341.1 - 0.00021 21.1 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KPA45341.1 - 0.00027 20.8 0.0 0.00052 19.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KPA45341.1 - 0.0032 16.9 0.0 0.027 13.8 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 KPA45341.1 - 0.0035 17.1 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit MeaB PF03308.16 KPA45341.1 - 0.005 15.9 0.0 0.009 15.0 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 KPA45341.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 KPA45341.1 - 0.0084 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_gamma3 PF12169.8 KPA45341.1 - 0.012 15.6 0.2 0.39 10.6 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III DEAD PF00270.29 KPA45341.1 - 0.015 15.1 0.1 0.39 10.5 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KPA45341.1 - 0.015 15.0 0.0 0.063 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KPA45341.1 - 0.016 14.7 0.0 3.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 KPA45341.1 - 0.016 15.1 0.2 0.065 13.1 0.1 2.0 1 1 1 2 2 2 0 NTPase KTI12 PF08433.10 KPA45341.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 KPA45341.1 - 0.019 15.3 0.1 0.057 13.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KPA45341.1 - 0.02 14.9 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 KPA45341.1 - 0.033 14.5 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain AAA_30 PF13604.6 KPA45341.1 - 0.05 13.3 0.1 0.21 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KPA45341.1 - 0.086 12.4 0.0 0.58 9.7 0.1 2.2 2 1 1 3 3 3 0 AAA domain DER1 PF04511.15 KPA45343.1 - 1.9e-25 89.9 9.4 2.2e-25 89.7 9.4 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 KPA45343.1 - 2.2e-05 24.5 2.0 3.7e-05 23.8 2.0 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KPA45343.1 - 0.025 15.2 3.4 0.025 15.2 3.4 2.5 2 1 1 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) CN_hydrolase PF00795.22 KPA45345.1 - 2.2e-14 53.4 0.0 2.6e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Mito_carr PF00153.27 KPA45345.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein DKCLD PF08068.12 KPA45348.1 - 6.2e-34 115.9 0.2 4.4e-32 109.9 0.2 2.7 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KPA45348.1 - 1.2e-22 80.9 0.3 2e-19 70.4 0.3 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KPA45348.1 - 5.1e-21 74.4 0.7 1.1e-20 73.4 0.7 1.6 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 KPA45348.1 - 6e-21 74.4 0.6 6e-21 74.4 0.6 1.8 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain UPF0113 PF03657.13 KPA45348.1 - 0.0016 18.6 0.0 0.0037 17.5 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain Med19 PF10278.9 KPA45348.1 - 0.7 9.8 10.8 1.6 8.6 10.8 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Glyco_hydro_43 PF04616.14 KPA45349.1 - 2.4e-23 82.9 0.0 4.1e-23 82.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 PTR2 PF00854.21 KPA45351.1 - 3.7e-37 128.1 1.4 5.9e-37 127.4 1.4 1.2 1 0 0 1 1 1 1 POT family PTR2 PF00854.21 KPA45352.1 - 1.5e-33 116.2 1.3 1.8e-33 116.0 1.3 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KPA45352.1 - 0.034 13.1 9.1 0.023 13.6 3.8 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily CCB1 PF12046.8 KPA45352.1 - 0.06 12.7 0.5 0.081 12.3 0.5 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B DUF3042 PF11240.8 KPA45352.1 - 0.075 13.1 0.3 14 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) SnoaL_4 PF13577.6 KPA45353.1 - 0.14 12.3 1.7 0.5 10.5 1.7 1.8 1 1 0 1 1 1 0 SnoaL-like domain DPM2 PF07297.12 KPA45355.1 - 8.8e-35 118.9 1.8 1e-34 118.7 1.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KPA45355.1 - 0.0001 22.2 0.4 0.00011 22.0 0.4 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 KPA45355.1 - 0.005 16.9 0.3 0.005 16.9 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) LapA_dom PF06305.11 KPA45355.1 - 0.0073 16.1 0.1 0.0073 16.1 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Phage_holin_3_6 PF07332.11 KPA45355.1 - 0.015 15.4 0.7 0.018 15.0 0.7 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MA3 PF02847.17 KPA45356.1 - 3.8e-24 84.8 0.0 1.1e-23 83.3 0.0 1.9 2 0 0 2 2 2 1 MA3 domain FAM176 PF14851.6 KPA45356.1 - 1.1 8.9 4.2 2.9 7.5 4.2 1.7 1 0 0 1 1 1 0 FAM176 family Ifi-6-16 PF06140.13 KPA45358.1 - 2.3e-11 43.4 47.0 3.4e-07 30.1 27.0 2.5 2 1 0 2 2 2 2 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 KPA45359.1 - 1.3e-09 37.8 31.5 1.3e-09 37.8 31.5 1.8 1 1 1 2 2 2 1 Interferon-induced 6-16 family Dus PF01207.17 KPA45360.1 - 2e-58 197.9 0.0 3.6e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) BKACE PF05853.12 KPA45360.1 - 0.019 14.3 0.1 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 beta-keto acid cleavage enzyme DHO_dh PF01180.21 KPA45360.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase CBP4 PF07960.11 KPA45360.1 - 0.14 12.0 5.3 0.73 9.7 3.1 2.3 2 0 0 2 2 2 0 CBP4 Fungal_trans_2 PF11951.8 KPA45362.1 - 2.1e-08 33.4 1.0 3.6e-08 32.6 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.29 KPA45364.1 - 1.3e-50 171.3 0.0 4.5e-42 143.6 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA45364.1 - 8.1e-10 38.4 0.6 2.8e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KPA45364.1 - 2.4e-08 34.6 0.1 0.00072 20.0 0.3 3.4 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KPA45364.1 - 2.4e-07 30.7 0.0 1.9e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KPA45364.1 - 1.3e-05 25.4 0.0 5.8e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KPA45364.1 - 0.00036 20.8 0.8 0.056 13.7 0.2 3.7 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KPA45364.1 - 0.00075 19.9 0.0 0.031 14.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 KPA45364.1 - 0.00078 19.5 0.0 0.012 15.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KPA45364.1 - 0.0059 17.1 0.0 0.037 14.6 0.0 2.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KPA45364.1 - 0.0087 15.8 0.0 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KPA45364.1 - 0.01 16.0 0.6 0.032 14.4 0.0 2.3 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 KPA45364.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KPA45364.1 - 0.027 14.7 0.6 0.21 11.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KPA45364.1 - 0.027 15.0 0.0 1.1 9.8 0.0 3.3 3 0 0 3 3 3 0 ABC transporter NACHT PF05729.12 KPA45364.1 - 0.041 13.8 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Bac_DnaA PF00308.18 KPA45364.1 - 0.042 13.7 0.0 7 6.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein Sigma54_activ_2 PF14532.6 KPA45364.1 - 0.05 13.7 0.0 1.7 8.7 0.0 2.7 2 1 1 3 3 3 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 KPA45364.1 - 0.06 13.0 0.0 3.4 7.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KPA45364.1 - 0.061 12.7 0.2 0.16 11.3 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KPA45364.1 - 0.061 13.3 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KPA45364.1 - 0.084 12.0 0.0 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KPA45364.1 - 0.086 12.3 0.0 0.37 10.3 0.0 2.1 3 0 0 3 3 2 0 P-loop containing dynein motor region Torsin PF06309.11 KPA45364.1 - 0.23 11.6 0.1 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Torsin AAA_11 PF13086.6 KPA45364.1 - 0.7 9.6 0.0 0.7 9.6 0.0 3.5 4 1 0 4 4 3 0 AAA domain adh_short PF00106.25 KPA45365.1 - 7.1e-27 94.1 0.0 4.2e-19 68.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPA45365.1 - 1.1e-22 80.8 0.2 4.4e-19 69.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA45365.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 KR domain DSBA PF01323.20 KPA45366.1 - 4.9e-17 62.3 0.0 1.4e-16 60.9 0.0 1.6 1 1 0 1 1 1 1 DSBA-like thioredoxin domain DHFR_1 PF00186.19 KPA45367.1 - 2.2e-34 118.5 0.0 4.5e-34 117.5 0.0 1.6 1 1 0 1 1 1 1 Dihydrofolate reductase ketoacyl-synt PF00109.26 KPA45368.1 - 4.2e-61 206.7 2.9 4.6e-60 203.3 0.3 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KPA45368.1 - 6.9e-36 122.8 1.8 1.4e-35 121.9 1.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Ubiq_cyt_C_chap PF03981.12 KPA45368.1 - 3.5e-30 104.9 0.0 9.4e-30 103.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Thiolase_N PF00108.23 KPA45368.1 - 3.9e-05 23.1 1.1 0.0012 18.3 0.2 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPA45368.1 - 0.064 12.9 2.7 0.21 11.3 0.4 2.9 3 1 0 3 3 3 0 Thiolase, C-terminal domain OPT PF03169.15 KPA45369.1 - 1.6e-169 565.5 43.0 3.7e-167 557.7 43.0 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DUF3270 PF11674.8 KPA45369.1 - 1 9.6 5.0 0.39 10.9 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Fungal_trans PF04082.18 KPA45370.1 - 4.4e-15 55.4 0.1 7.3e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA45370.1 - 1.2e-06 28.5 12.5 2.4e-06 27.5 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Biotin_lipoyl PF00364.22 KPA45371.1 - 2e-20 72.4 1.1 3.6e-20 71.5 1.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KPA45371.1 - 2e-11 44.0 0.1 5.1e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KPA45371.1 - 0.00032 20.4 0.0 0.0025 17.6 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KPA45371.1 - 0.073 13.8 0.1 0.42 11.3 0.0 2.2 1 1 1 2 2 2 0 HlyD family secretion protein QRPTase_N PF02749.16 KPA45371.1 - 0.15 12.1 0.0 0.65 10.1 0.0 2.0 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain CCER1 PF15482.6 KPA45373.1 - 0.12 12.2 0.3 0.16 11.8 0.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 LRR_4 PF12799.7 KPA45374.1 - 1.3e-11 44.5 2.8 0.00075 19.8 0.1 3.9 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPA45374.1 - 5e-10 39.0 9.0 9.1e-07 28.6 2.8 3.4 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KPA45374.1 - 0.0044 17.4 8.2 26 5.9 0.1 5.5 4 2 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.6 KPA45374.1 - 0.011 15.2 0.3 0.027 14.0 0.3 1.7 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 KPA45374.1 - 2 8.7 8.9 1.1e+02 3.3 0.1 5.1 6 0 0 6 6 6 0 Leucine Rich repeat zf-HC5HC2H_2 PF13832.6 KPA45375.1 - 4.3e-33 113.8 6.3 4.3e-33 113.8 6.3 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KPA45375.1 - 3.4e-29 102.2 1.7 3.4e-29 102.2 1.7 2.8 3 1 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KPA45375.1 - 2.6e-26 91.7 5.6 2.6e-26 91.7 5.6 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KPA45375.1 - 1.2e-14 53.5 2.0 1.2e-14 53.5 2.0 2.1 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KPA45375.1 - 4.6e-09 36.0 25.0 3.2e-08 33.3 11.7 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KPA45375.1 - 3.6 7.2 14.7 0.015 15.0 2.1 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.11 KPA45375.1 - 5.9 7.3 23.0 0.17 12.2 8.0 2.7 2 1 0 2 2 2 0 RING-like domain Metallophos PF00149.28 KPA45376.1 - 3.5e-40 138.7 0.1 4.5e-40 138.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KPA45376.1 - 2.9e-23 82.0 1.8 4.3e-23 81.5 1.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Rdx PF10262.9 KPA45377.1 - 6.8e-34 115.9 0.0 9e-34 115.5 0.0 1.2 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.22 KPA45378.1 - 1.2e-24 86.1 0.0 1.6e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 GGL domain PCI PF01399.27 KPA45379.1 - 1.9e-08 34.8 0.5 2.3e-07 31.3 0.0 2.9 2 0 0 2 2 2 1 PCI domain WSC PF01822.19 KPA45380.1 - 1.8e-33 114.6 27.8 3.9e-20 71.8 7.1 6.5 6 2 0 6 6 6 2 WSC domain Lamprin PF06403.11 KPA45380.1 - 0.077 13.0 0.6 9.5 6.2 0.1 2.5 2 0 0 2 2 2 0 Lamprin Herpes_LMP1 PF05297.11 KPA45380.1 - 2.8 7.0 16.2 4.6 6.3 16.2 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Steroid_dh PF02544.16 KPA45381.1 - 2.1e-11 44.0 1.0 2.1e-11 44.0 1.0 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase 2OG-FeII_Oxy_2 PF13532.6 KPA45382.1 - 0.0081 16.4 0.0 0.095 12.9 0.0 1.9 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 KPA45383.1 - 7.9e-20 71.2 0.0 1.5e-12 47.9 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA45383.1 - 1.5e-13 50.9 0.0 1e-07 32.4 0.1 4.7 3 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KPA45383.1 - 4.8e-12 45.7 1.6 0.00016 21.9 0.2 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KPA45383.1 - 4.5e-11 42.0 0.2 0.00055 20.2 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KPA45383.1 - 2.2e-09 37.4 0.8 0.00038 20.7 0.2 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) MMR_HSR1_Xtn PF16897.5 KPA45384.1 - 7.1e-41 138.5 0.7 5.8e-40 135.6 0.3 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KPA45384.1 - 1.2e-21 76.5 0.1 2.4e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KPA45384.1 - 1.6e-20 73.3 0.0 5.5e-20 71.6 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPA45384.1 - 2.6e-09 36.8 0.1 1.3e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KPA45384.1 - 0.00021 21.4 0.1 0.052 13.6 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KPA45384.1 - 0.00055 19.5 0.1 5.6 6.5 0.0 4.0 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KPA45384.1 - 0.0089 15.0 0.1 0.025 13.6 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBS PF00571.28 KPA45384.1 - 0.025 15.0 0.1 0.075 13.5 0.1 1.8 1 0 0 1 1 1 0 CBS domain RsgA_GTPase PF03193.16 KPA45384.1 - 0.033 14.1 0.4 6.2 6.7 0.1 2.8 2 1 0 2 2 2 0 RsgA GTPase AIG1 PF04548.16 KPA45384.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Arf PF00025.21 KPA45384.1 - 0.13 11.8 0.1 10 5.5 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family CENP-B_N PF04218.13 KPA45385.1 - 6.6e-11 41.7 0.2 1.2e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 KPA45385.1 - 9.1e-11 41.6 0.1 1.2e-09 38.1 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain MarR PF01047.22 KPA45385.1 - 0.011 15.7 0.1 0.037 14.0 0.0 2.0 2 0 0 2 2 2 0 MarR family HTH_Tnp_4 PF13613.6 KPA45385.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.7 KPA45385.1 - 0.02 14.7 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.6 KPA45385.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KPA45385.1 - 0.085 12.7 0.3 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain PXA PF02194.15 KPA45386.1 - 4.9e-44 150.5 0.4 4.9e-44 150.5 0.4 1.7 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KPA45386.1 - 0.0021 18.6 0.0 0.0074 16.8 0.0 1.9 2 0 0 2 2 2 1 Sorting nexin C terminal zf-Mss51 PF13824.6 KPA45387.1 - 4.3e-30 103.6 8.9 8.7e-30 102.6 8.9 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KPA45387.1 - 0.018 15.1 2.2 0.038 14.1 2.2 1.5 1 0 0 1 1 1 0 MYND finger DTW PF03942.15 KPA45387.1 - 0.061 13.0 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 DTW domain PROCT PF08084.11 KPA45387.1 - 0.13 12.2 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 PROCT (NUC072) domain MMS1_N PF10433.9 KPA45388.1 - 1.3e-156 522.1 0.0 2.6e-156 521.1 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KPA45388.1 - 8.6e-102 340.7 0.0 3.2e-101 338.9 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region UBM PF14377.6 KPA45388.1 - 0.48 9.9 3.3 1.1 8.7 0.5 2.7 2 0 0 2 2 2 0 Ubiquitin binding region LysM PF01476.20 KPA45389.1 - 0.00036 20.5 0.0 0.0008 19.4 0.0 1.6 2 0 0 2 2 2 1 LysM domain UBA_4 PF14555.6 KPA45389.1 - 0.00037 20.2 0.0 0.00071 19.3 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain HopA1 PF17914.1 KPA45389.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 HopA1 effector protein family DUF2040 PF09745.9 KPA45390.1 - 7.8e-38 129.3 28.0 7.8e-38 129.3 28.0 3.9 3 2 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Lipase_GDSL_3 PF14606.6 KPA45390.1 - 4.8 7.3 5.7 0.46 10.6 0.5 1.9 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family zf-Tim10_DDP PF02953.15 KPA45391.1 - 5.7e-23 80.3 2.0 6.8e-23 80.1 2.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger ADH_zinc_N PF00107.26 KPA45392.1 - 1.4e-14 54.2 0.0 6e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPA45392.1 - 2.5e-08 35.1 0.0 3.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPA45392.1 - 7.7e-06 25.8 0.2 2.2e-05 24.3 0.2 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Lectin_leg-like PF03388.13 KPA45393.1 - 8.4e-64 215.1 0.0 1.4e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KPA45393.1 - 7.4e-05 22.4 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain ATG27 PF09451.10 KPA45393.1 - 0.085 12.7 0.2 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 Pkinase PF00069.25 KPA45394.1 - 2.7e-74 249.8 0.0 3.6e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA45394.1 - 1.7e-38 132.4 0.0 2.4e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA45394.1 - 1.6e-08 34.2 0.0 3.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Rad21_Rec8 PF04824.16 KPA45394.1 - 0.16 11.3 0.3 0.34 10.2 0.3 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein TFIIA PF03153.13 KPA45394.1 - 0.35 10.8 19.2 0.48 10.4 19.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CorA PF01544.18 KPA45395.1 - 5.6e-05 22.6 0.0 0.00013 21.4 0.0 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 KPA45395.1 - 0.083 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5531 PF17671.1 KPA45395.1 - 1.8 8.4 5.5 0.42 10.5 1.6 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5531) LMBR1 PF04791.16 KPA45396.1 - 7.3e-108 361.7 11.5 8.3e-108 361.5 11.5 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Hat1_N PF10394.9 KPA45397.1 - 8.4e-47 159.4 0.0 1.2e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.7 KPA45397.1 - 0.04 13.9 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain P5CR_dimer PF14748.6 KPA45398.1 - 7.3e-33 112.9 1.6 1.9e-32 111.6 1.6 1.8 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KPA45398.1 - 7.6e-10 39.2 0.6 5.8e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent CTK3 PF12243.8 KPA45399.1 - 5.2e-48 162.1 0.0 9.3e-48 161.3 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KPA45399.1 - 1.1e-18 67.1 14.9 1.1e-18 67.1 14.9 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus LID PF17916.1 KPA45399.1 - 0.092 12.4 0.6 0.22 11.2 0.6 1.6 1 0 0 1 1 1 0 LIM interaction domain (LID) Ribosomal_L12 PF00542.19 KPA45400.1 - 3.8e-20 72.0 2.4 3.8e-20 72.0 2.4 2.6 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KPA45400.1 - 1.6e-12 46.9 14.1 7.8e-12 44.7 10.5 3.4 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 KPA45400.1 - 0.022 14.6 1.2 0.049 13.4 0.1 2.0 2 1 0 2 2 2 0 Stage VI sporulation protein F Ribosomal_60s PF00428.19 KPA45400.1 - 0.28 11.8 9.7 0.049 14.2 5.7 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein AAA_5 PF07728.14 KPA45401.1 - 9.4e-128 420.9 0.0 6.7e-22 78.0 0.0 10.0 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KPA45401.1 - 2.5e-51 172.3 3.9 7.1e-20 71.2 0.0 5.9 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KPA45401.1 - 2.9e-32 110.9 0.3 3.8e-31 107.3 0.0 2.9 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_3 PF07726.11 KPA45401.1 - 6.8e-32 110.1 0.0 1.6e-09 37.7 0.0 6.9 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPA45401.1 - 9.8e-30 104.2 18.9 2.5e-07 31.2 0.3 9.8 7 3 0 7 7 6 6 AAA ATPase domain AAA PF00004.29 KPA45401.1 - 3e-29 102.1 0.0 0.00035 21.0 0.0 7.1 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KPA45401.1 - 9e-28 97.0 1.3 4.4e-06 26.3 0.0 6.9 6 1 0 6 6 6 4 P-loop containing dynein motor region Dynein_heavy PF03028.15 KPA45401.1 - 1.4e-24 86.5 0.0 0.0026 17.9 0.0 8.1 8 0 0 8 8 6 4 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 KPA45401.1 - 5e-23 81.6 0.1 0.01 14.9 0.0 8.8 8 1 0 8 8 8 6 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KPA45401.1 - 3.7e-21 75.8 0.5 0.0018 18.6 0.0 8.3 8 0 0 8 8 6 4 AAA domain Sigma54_activat PF00158.26 KPA45401.1 - 4.8e-19 68.7 0.0 0.0076 16.0 0.0 6.2 6 0 0 6 6 5 5 Sigma-54 interaction domain TsaE PF02367.17 KPA45401.1 - 3.4e-18 65.8 3.6 0.00093 19.2 0.3 6.5 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KPA45401.1 - 4.3e-17 62.6 0.9 0.014 15.6 0.0 7.2 8 1 0 8 8 6 4 AAA domain AAA_18 PF13238.6 KPA45401.1 - 7.7e-17 62.1 1.7 0.048 14.2 0.0 7.8 8 0 0 8 8 5 3 AAA domain AAA_14 PF13173.6 KPA45401.1 - 8.5e-16 58.2 0.0 0.015 15.4 0.0 6.6 6 0 0 6 6 5 3 AAA domain NACHT PF05729.12 KPA45401.1 - 3.7e-15 56.2 2.7 0.12 12.3 0.0 6.1 5 0 0 5 5 5 4 NACHT domain RuvB_N PF05496.12 KPA45401.1 - 3.8e-14 52.7 2.7 0.042 13.6 0.0 6.4 7 0 0 7 7 6 3 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 KPA45401.1 - 1.5e-13 51.0 3.4 0.037 13.9 0.3 6.9 7 0 0 7 7 7 4 RsgA GTPase RNA_helicase PF00910.22 KPA45401.1 - 3.4e-13 49.9 1.1 0.24 11.8 0.0 6.8 6 0 0 6 6 6 3 RNA helicase T2SSE PF00437.20 KPA45401.1 - 5.4e-13 48.6 1.6 0.013 14.6 0.0 5.3 5 0 0 5 5 5 3 Type II/IV secretion system protein ABC_tran PF00005.27 KPA45401.1 - 2.1e-12 47.7 5.2 0.0063 17.0 0.0 7.4 7 1 0 7 7 6 2 ABC transporter Sigma54_activ_2 PF14532.6 KPA45401.1 - 1.1e-11 45.0 0.8 0.0057 16.8 0.0 5.9 6 0 0 6 6 5 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 KPA45401.1 - 1.3e-11 44.1 4.2 0.0065 15.8 0.0 6.0 6 0 0 6 6 5 3 Zeta toxin AAA_28 PF13521.6 KPA45401.1 - 2.4e-11 44.1 2.2 0.79 10.0 0.0 6.9 6 0 0 6 6 6 1 AAA domain IstB_IS21 PF01695.17 KPA45401.1 - 5.1e-10 39.4 0.3 0.39 10.4 0.1 6.1 6 0 0 6 6 6 2 IstB-like ATP binding protein NTPase_1 PF03266.15 KPA45401.1 - 5.2e-10 39.5 5.9 0.91 9.4 0.1 6.0 5 0 0 5 5 5 4 NTPase Rad17 PF03215.15 KPA45401.1 - 7.8e-10 39.0 0.1 0.22 11.4 0.0 5.6 5 0 0 5 5 5 2 Rad17 P-loop domain Mg_chelatase PF01078.21 KPA45401.1 - 1.9e-09 37.2 0.7 6.5 6.1 0.1 7.9 8 0 0 8 8 7 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KPA45401.1 - 4e-09 36.3 0.3 0.79 9.3 0.0 5.6 5 0 0 5 5 5 1 AAA domain AAA_19 PF13245.6 KPA45401.1 - 2.6e-08 34.3 4.1 2 8.8 0.0 6.5 6 0 0 6 6 5 1 AAA domain AAA_29 PF13555.6 KPA45401.1 - 1e-07 31.6 0.0 5 7.0 0.0 6.2 6 0 0 6 6 6 0 P-loop containing region of AAA domain DUF815 PF05673.13 KPA45401.1 - 3.3e-07 29.7 1.2 0.98 8.5 0.0 4.9 5 0 0 5 5 5 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 KPA45401.1 - 4.9e-07 29.2 3.2 0.37 9.9 0.0 5.8 6 0 0 6 6 5 1 NB-ARC domain ResIII PF04851.15 KPA45401.1 - 7.1e-07 29.4 0.2 0.82 9.6 0.0 5.5 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KPA45401.1 - 7.2e-07 29.4 0.0 2.6 7.9 0.0 5.8 6 0 0 6 6 5 1 ATPase domain predominantly from Archaea SRP54 PF00448.22 KPA45401.1 - 8.5e-07 28.8 3.0 0.52 9.9 0.1 5.2 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain TniB PF05621.11 KPA45401.1 - 9e-07 28.5 0.1 4 6.8 0.0 6.0 6 0 0 6 6 5 0 Bacterial TniB protein PduV-EutP PF10662.9 KPA45401.1 - 1.1e-06 28.5 1.7 0.59 9.9 0.0 4.8 5 0 0 5 5 4 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KPA45401.1 - 1.1e-06 28.7 0.3 22 5.1 0.0 5.9 5 0 0 5 5 5 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KPA45401.1 - 1.1e-06 28.5 0.1 3.5 7.3 0.0 6.6 7 0 0 7 7 6 0 AAA domain TIP49 PF06068.13 KPA45401.1 - 2e-06 27.2 0.3 2.6 7.2 0.0 4.6 5 0 0 5 5 5 1 TIP49 P-loop domain dNK PF01712.19 KPA45401.1 - 1e-05 25.5 3.7 5.7 6.7 0.0 5.5 5 0 0 5 5 5 0 Deoxynucleoside kinase Roc PF08477.13 KPA45401.1 - 1.9e-05 24.9 1.4 7.8 6.7 0.1 5.5 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 KPA45401.1 - 2.4e-05 24.4 0.1 6.8 6.8 0.0 5.3 5 0 0 5 5 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain KAP_NTPase PF07693.14 KPA45401.1 - 0.00022 20.6 0.0 3.3 6.9 0.0 4.6 5 0 0 5 5 5 0 KAP family P-loop domain Viral_helicase1 PF01443.18 KPA45401.1 - 0.00028 20.7 0.0 4.4 7.0 0.0 4.7 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 KPA45401.1 - 0.00038 20.3 3.4 6.2 6.5 0.0 4.8 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein Bac_DnaA PF00308.18 KPA45401.1 - 0.0011 18.9 0.6 7.9 6.2 0.0 4.9 6 0 0 6 6 4 0 Bacterial dnaA protein DUF87 PF01935.17 KPA45401.1 - 0.0022 18.2 0.7 9.1 6.3 0.0 4.7 4 0 0 4 4 2 0 Helicase HerA, central domain MeaB PF03308.16 KPA45401.1 - 0.0022 17.0 2.0 1.6 7.6 0.1 4.1 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 KPA45401.1 - 0.0056 16.1 0.0 24 4.1 0.0 4.2 4 0 0 4 4 4 0 KaiC VWA PF00092.28 KPA45401.1 - 0.0067 16.7 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain cobW PF02492.19 KPA45401.1 - 0.0072 15.9 6.2 29 4.2 0.0 5.6 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase3 PF18751.1 KPA45401.1 - 0.0093 15.9 0.1 8.6 6.2 0.0 4.0 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 CPT PF07931.12 KPA45401.1 - 0.01 15.7 0.7 33 4.3 0.0 5.1 5 1 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein DEAD PF00270.29 KPA45401.1 - 0.015 15.1 0.0 12 5.6 0.0 3.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase Septin PF00735.18 KPA45401.1 - 0.017 14.4 1.3 14 4.8 0.1 4.1 5 0 0 5 5 4 0 Septin VWA_2 PF13519.6 KPA45401.1 - 0.021 15.5 0.0 0.13 12.9 0.0 2.6 1 0 0 1 1 1 0 von Willebrand factor type A domain PhoH PF02562.16 KPA45401.1 - 0.04 13.4 0.2 16 4.9 0.0 3.9 4 0 0 4 4 4 0 PhoH-like protein Thymidylate_kin PF02223.17 KPA45401.1 - 0.042 13.5 6.5 1.8 8.2 0.0 5.3 6 0 0 6 6 4 0 Thymidylate kinase DUF3263 PF11662.8 KPA45401.1 - 0.08 12.8 0.0 2.7 7.9 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) PRK PF00485.18 KPA45401.1 - 0.086 12.6 0.1 13 5.5 0.0 3.3 4 0 0 4 4 2 0 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.18 KPA45401.1 - 0.1 12.1 0.6 95 2.5 0.0 4.4 4 0 0 4 4 4 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 KPA45401.1 - 0.13 11.6 0.9 27 4.0 0.0 3.8 4 0 0 4 4 3 0 FtsK/SpoIIIE family SKI PF01202.22 KPA45401.1 - 0.14 12.3 4.5 8.8 6.4 0.0 4.5 5 0 0 5 5 3 0 Shikimate kinase Hpr_kinase_C PF07475.12 KPA45401.1 - 0.83 9.2 3.5 1.4 8.4 0.2 2.9 4 0 0 4 4 2 0 HPr Serine kinase C-terminal domain Isochorismatase PF00857.20 KPA45402.1 - 7.4e-22 78.3 0.0 1.2e-21 77.7 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DUF919 PF06034.11 KPA45403.1 - 0.1 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Lipase_GDSL_2 PF13472.6 KPA45404.1 - 3.7e-23 82.9 0.0 5.2e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA45404.1 - 1.4e-15 57.8 0.0 1.6e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BP28CT PF08146.12 KPA45405.1 - 2.5e-42 144.4 0.3 3e-40 137.7 0.1 3.1 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KPA45405.1 - 6.5e-23 81.3 9.6 3.2e-22 79.1 0.1 5.4 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KPA45405.1 - 6e-08 32.3 9.3 0.0022 18.1 0.1 6.3 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KPA45405.1 - 0.012 16.1 16.5 0.12 12.9 0.8 6.8 5 1 0 5 5 5 0 HEAT-like repeat RTP1_C1 PF10363.9 KPA45405.1 - 0.015 15.4 2.8 2.6 8.3 0.0 5.3 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 KPA45405.1 - 0.016 15.5 20.7 0.71 10.3 0.1 7.2 8 1 1 9 9 9 0 HEAT repeats HK PF02110.15 KPA45406.1 - 1.7e-76 256.9 2.8 2.9e-76 256.1 2.8 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KPA45406.1 - 1.3e-56 190.8 0.1 2.5e-56 189.9 0.1 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Pyr_redox_2 PF07992.14 KPA45406.1 - 4.2e-46 157.5 0.1 1.4e-45 155.8 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA45406.1 - 4.1e-11 43.3 0.0 1.9e-08 34.7 0.0 3.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA45406.1 - 1.3e-06 27.9 0.4 0.00067 19.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Phos_pyr_kin PF08543.12 KPA45406.1 - 0.0016 17.9 0.1 0.003 17.0 0.1 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ADH_zinc_N PF00107.26 KPA45406.1 - 0.007 16.3 0.9 0.47 10.4 0.4 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 KPA45407.1 - 0.067 13.3 8.6 0.11 12.6 8.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.21 KPA45408.1 - 8.9e-84 281.7 0.0 1.2e-83 281.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPA45408.1 - 8.7e-05 21.6 0.0 0.00029 19.9 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KPA45408.1 - 0.00015 20.4 0.0 0.00028 19.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KPA45408.1 - 0.0054 16.1 0.2 0.0092 15.3 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SNF2_N PF00176.23 KPA45409.1 - 7e-45 153.3 0.0 1.5e-44 152.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA45409.1 - 9e-20 71.1 0.3 4.7e-19 68.8 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA45409.1 - 2.9e-08 33.9 0.0 9.1e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KPA45409.1 - 0.00014 21.6 0.2 0.0031 17.2 0.2 2.5 1 1 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 KPA45409.1 - 0.006 15.8 0.3 0.012 14.8 0.3 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SAM_Ste50p PF09235.10 KPA45409.1 - 0.039 14.2 0.1 0.14 12.4 0.1 2.0 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Arm_3 PF16186.5 KPA45409.1 - 0.14 11.8 1.0 0.35 10.4 1.0 1.6 1 0 0 1 1 1 0 Atypical Arm repeat GSH_synth_ATP PF03917.17 KPA45410.1 - 6.6e-141 469.4 0.0 7.5e-141 469.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KPA45410.1 - 1.6e-33 115.2 0.0 2.9e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SSB PF00436.25 KPA45411.1 - 4.3e-19 68.5 0.0 5.2e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF4741 PF15897.5 KPA45411.1 - 0.024 14.4 0.1 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) STE3 PF02076.15 KPA45412.1 - 1.2e-64 218.4 18.0 1.6e-64 217.9 18.0 1.2 1 0 0 1 1 1 1 Pheromone A receptor 7tm_1 PF00001.21 KPA45412.1 - 0.013 14.9 7.3 0.019 14.3 7.3 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Jagunal PF07086.12 KPA45412.1 - 0.15 12.1 2.6 0.77 9.8 0.2 2.4 1 1 1 2 2 2 0 Jagunal, ER re-organisation during oogenesis DUF4203 PF13886.6 KPA45413.1 - 7.2e-53 179.3 29.6 9.4e-53 178.9 29.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Osw5 PF17062.5 KPA45414.1 - 0.09 12.9 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 Outer spore wall 5 BLOC1_2 PF10046.9 KPA45414.1 - 0.096 13.0 0.7 0.32 11.3 0.4 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4510 PF14971.6 KPA45414.1 - 0.097 13.0 4.0 0.18 12.1 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Matrilin_ccoil PF10393.9 KPA45414.1 - 0.2 11.6 0.6 0.47 10.4 0.6 1.6 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Prominin PF05478.11 KPA45414.1 - 0.26 9.2 1.1 0.37 8.7 1.1 1.1 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 KPA45414.1 - 0.74 8.6 5.7 1.1 8.1 5.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1993 PF09351.10 KPA45414.1 - 0.75 9.9 3.1 7.5 6.7 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) NPV_P10 PF05531.12 KPA45414.1 - 1.6 9.3 4.1 3.1 8.3 0.2 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CCDC-167 PF15188.6 KPA45414.1 - 7.2 7.0 8.1 0.95 9.9 3.7 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Aldose_epim PF01263.20 KPA45415.1 - 1.9e-63 214.6 0.0 2.4e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase SWM_repeat PF13753.6 KPA45415.1 - 0.13 12.4 1.2 0.59 10.3 0.0 2.3 2 0 0 2 2 2 0 Putative flagellar system-associated repeat Cas_Cas1 PF01867.16 KPA45416.1 - 0.065 12.4 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas1 SOG2 PF10428.9 KPA45416.1 - 8.3 5.5 13.2 10 5.2 13.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein UPF0203 PF05254.12 KPA45417.1 - 7.8e-27 93.3 6.4 9.2e-27 93.1 6.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KPA45417.1 - 0.00037 20.8 2.9 0.00085 19.6 2.9 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KPA45417.1 - 0.0004 20.3 6.3 0.0054 16.7 0.4 2.4 1 1 2 3 3 3 3 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 KPA45417.1 - 0.067 13.4 6.6 0.06 13.5 4.8 1.8 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 KPA45417.1 - 0.42 11.5 6.3 1 10.3 2.3 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5339) Gpi1 PF05024.15 KPA45418.1 - 5.8e-78 261.3 6.2 1.2e-77 260.3 6.2 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.21 KPA45418.1 - 0.011 15.1 0.1 0.03 13.7 0.1 1.7 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Sof1 PF04158.14 KPA45418.1 - 0.015 15.6 1.2 0.031 14.5 1.2 1.6 1 0 0 1 1 1 0 Sof1-like domain DUF92 PF01940.16 KPA45418.1 - 0.15 11.5 0.2 0.44 9.9 0.1 1.9 2 0 0 2 2 2 0 Integral membrane protein DUF92 TBCC PF07986.12 KPA45419.1 - 1e-29 102.7 0.0 2e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KPA45419.1 - 4.1e-09 36.9 0.0 7.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain F_actin_bind PF08919.10 KPA45419.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 F-actin binding Med9 PF07544.13 KPA45420.1 - 1.7e-20 72.9 0.2 3.8e-20 71.7 0.2 1.7 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Spc29 PF17082.5 KPA45420.1 - 0.0029 17.5 0.0 0.0039 17.1 0.0 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 Fib_alpha PF08702.10 KPA45420.1 - 0.024 14.8 0.1 0.032 14.4 0.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 KPA45420.1 - 0.027 14.3 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Med21 PF11221.8 KPA45420.1 - 0.034 14.4 1.3 0.036 14.3 1.3 1.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DivIC PF04977.15 KPA45420.1 - 0.054 13.3 1.1 0.086 12.6 1.1 1.3 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 KPA45420.1 - 0.13 12.9 3.4 0.49 11.1 2.7 2.3 2 1 1 3 3 3 0 SlyX iPGM_N PF06415.13 KPA45421.1 - 1e-73 247.4 0.0 1.4e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KPA45421.1 - 5.2e-68 229.1 0.0 5.9e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KPA45421.1 - 9.9e-05 21.9 0.0 0.00097 18.6 0.0 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPA45421.1 - 0.00038 20.2 0.0 0.0011 18.6 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase FRQ PF09421.10 KPA45422.1 - 0 1594.5 55.8 0 1594.3 55.8 1.0 1 0 0 1 1 1 1 Frequency clock protein Prenylcys_lyase PF07156.14 KPA45423.1 - 7.2e-92 308.3 0.0 1e-91 307.8 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KPA45423.1 - 3e-12 46.6 0.0 6.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KPA45423.1 - 5e-08 32.7 0.0 8.6e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KPA45423.1 - 6.5e-05 22.7 0.2 0.00034 20.3 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPA45423.1 - 0.00058 19.9 0.2 0.0014 18.7 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPA45423.1 - 0.0014 17.9 0.2 0.0076 15.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KPA45423.1 - 0.0045 16.6 0.3 2.1 8.0 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 KPA45423.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KPA45423.1 - 0.23 10.5 0.4 0.47 9.5 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain VID27 PF08553.10 KPA45424.1 - 2e-192 638.9 0.1 2.6e-192 638.5 0.1 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KPA45424.1 - 5.8e-74 247.6 0.6 5.8e-74 247.6 0.6 3.5 4 0 0 4 4 4 1 VID27 N-terminal region VID27_PH PF17747.1 KPA45424.1 - 2.1e-42 143.8 0.3 7.6e-42 142.0 0.1 2.1 2 0 0 2 2 2 1 VID27 PH-like domain CDC45 PF02724.14 KPA45424.1 - 5 5.3 8.2 7.6 4.7 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KPA45424.1 - 7.4 4.5 16.0 0.12 10.4 8.4 1.7 2 0 0 2 2 2 0 DNA polymerase phi Glyco_transf_20 PF00982.21 KPA45425.1 - 8e-197 654.6 0.0 9.2e-197 654.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KPA45425.1 - 0.026 14.2 0.1 0.094 12.4 0.1 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain DNA_pol_A_exo1 PF01612.20 KPA45426.1 - 8.6e-40 136.3 0.6 1.4e-39 135.7 0.6 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KPA45426.1 - 3.4e-26 91.7 3.0 3.9e-26 91.6 0.1 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KPA45426.1 - 3.2e-11 43.1 0.1 1.6e-10 40.8 0.0 2.3 2 0 0 2 2 2 1 HRDC domain YL1 PF05764.13 KPA45426.1 - 0.23 11.5 33.0 0.032 14.4 27.8 2.1 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 KPA45426.1 - 3.3 5.9 26.0 6.4 4.9 26.0 1.4 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 KPA45426.1 - 4.6 7.1 31.6 0.27 11.1 25.1 2.0 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal MRP-S26 PF14943.6 KPA45426.1 - 5.7 6.8 20.2 14 5.5 20.2 1.7 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 ATP-synt_C PF00137.21 KPA45427.1 - 8.7e-11 42.0 13.5 8.7e-11 42.0 13.5 1.8 2 0 0 2 2 2 1 ATP synthase subunit C IncE PF17627.2 KPA45427.1 - 0.0077 16.3 0.2 0.0091 16.0 0.2 1.2 1 0 0 1 1 1 1 Inclusion membrane protein E MOZ_SAS PF01853.18 KPA45428.1 - 3e-55 186.6 0.0 4.5e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KPA45428.1 - 2e-08 33.7 0.2 0.004 16.7 0.0 2.3 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_1 PF00583.25 KPA45428.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family LRR_6 PF13516.6 KPA45429.1 - 3.3e-08 32.9 6.0 0.048 13.7 0.0 5.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 KPA45429.1 - 0.0019 18.4 0.0 21 6.2 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_4 PF12799.7 KPA45429.1 - 0.021 15.2 0.0 10 6.7 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Rpn3_C PF08375.11 KPA45430.1 - 1.8e-25 89.1 1.7 1.8e-25 89.1 1.7 2.1 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KPA45430.1 - 4e-21 75.5 0.1 7.5e-20 71.4 0.0 2.5 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KPA45430.1 - 0.0051 16.8 0.1 0.023 14.8 0.1 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPA45430.1 - 0.16 12.6 0.7 0.74 10.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIID_20kDa PF03847.13 KPA45431.1 - 4.5e-17 62.3 0.0 7.3e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Cnl2_NKP2 PF09447.10 KPA45433.1 - 1.2e-24 86.2 0.7 1.2e-24 86.2 0.7 2.4 3 0 0 3 3 3 1 Cnl2/NKP2 family protein Prefoldin_2 PF01920.20 KPA45433.1 - 0.038 13.9 2.2 0.19 11.7 2.2 2.1 1 1 0 1 1 1 0 Prefoldin subunit HisKA_3 PF07730.13 KPA45433.1 - 0.23 12.0 7.9 2 9.0 0.3 2.4 2 0 0 2 2 2 0 Histidine kinase FUSC PF04632.12 KPA45433.1 - 0.28 9.7 3.3 0.34 9.4 3.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family IFT20 PF14931.6 KPA45433.1 - 0.73 10.0 6.4 1.5 9.0 1.6 2.2 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 APG6_N PF17675.1 KPA45433.1 - 2.4 8.7 10.7 15 6.1 9.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region AMP-binding PF00501.28 KPA45434.1 - 4e-70 236.5 0.0 6.8e-70 235.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KPA45434.1 - 4.3e-69 232.6 0.0 6.8e-69 231.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KPA45434.1 - 1.1e-09 38.4 0.0 2.6e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KPA45434.1 - 1.6e-08 33.9 0.1 4.5e-08 32.4 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPA45434.1 - 1.6e-08 34.3 0.0 3.6e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KPA45434.1 - 3.5e-05 24.7 0.0 0.00017 22.5 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 KPA45434.1 - 0.028 14.3 0.1 0.32 10.9 0.1 2.6 2 1 0 2 2 2 0 NAD(P)H-binding MRG PF05712.13 KPA45435.1 - 1.9e-59 200.3 0.8 2.9e-59 199.7 0.8 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KPA45435.1 - 9.5e-08 31.8 0.6 1.7e-07 31.0 0.6 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Ribosomal_L30 PF00327.20 KPA45436.1 - 3.2e-16 59.0 0.1 4.1e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Citrate_synt PF00285.21 KPA45437.1 - 7.7e-20 71.3 0.0 6.9e-17 61.6 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KPA45437.1 - 4.1e-18 65.8 0.0 1.3e-17 64.3 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 KPA45437.1 - 1.3e-15 57.5 0.1 3e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KPA45437.1 - 0.00034 20.4 0.0 0.0038 17.0 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain DapB_N PF01113.20 KPA45437.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Citrate_bind PF16114.5 KPA45438.1 - 1.6e-85 285.1 0.0 2.3e-85 284.6 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KPA45438.1 - 2.1e-08 33.9 0.0 3.1e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Glyco_hydro_72 PF03198.14 KPA45440.1 - 1.3e-112 376.1 0.2 1.7e-112 375.7 0.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 KPA45440.1 - 0.0029 16.8 1.8 0.0074 15.4 1.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DNA_pol_phi PF04931.13 KPA45440.1 - 1.6 6.7 3.2 2.2 6.3 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Septin PF00735.18 KPA45441.1 - 1.3e-112 375.7 0.7 1.5e-112 375.5 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KPA45441.1 - 2.9e-08 33.8 0.0 5.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA45441.1 - 8e-07 29.1 0.1 8.4e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KPA45441.1 - 1.4e-06 28.0 0.3 0.0016 18.1 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KPA45441.1 - 2e-06 27.3 0.0 3.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 KPA45441.1 - 0.0006 20.2 0.0 0.0024 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 KPA45441.1 - 0.00063 19.8 0.2 0.89 9.6 0.1 2.6 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 KPA45441.1 - 0.002 17.4 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KPA45441.1 - 0.0056 17.0 0.0 0.013 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KPA45441.1 - 0.0061 16.1 0.1 0.043 13.3 0.0 2.3 2 1 0 2 2 2 1 P-loop containing dynein motor region Gtr1_RagA PF04670.12 KPA45441.1 - 0.0063 15.9 0.1 0.24 10.7 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KPA45441.1 - 0.007 16.9 0.3 0.015 15.8 0.3 1.8 1 1 0 1 1 1 1 ABC transporter Ras PF00071.22 KPA45441.1 - 0.02 14.5 0.0 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 Ras family G-alpha PF00503.20 KPA45441.1 - 0.033 13.4 0.6 0.13 11.4 0.6 1.9 1 1 0 1 1 1 0 G-protein alpha subunit Roc PF08477.13 KPA45441.1 - 0.043 14.0 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KPA45441.1 - 0.044 13.1 0.1 0.089 12.1 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Microtub_bd PF16796.5 KPA45441.1 - 0.055 13.4 0.1 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Microtubule binding AAA_23 PF13476.6 KPA45441.1 - 0.086 13.3 0.5 0.14 12.7 0.4 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KPA45441.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KPA45441.1 - 0.12 11.5 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1542 PF07564.11 KPA45441.1 - 0.16 12.1 0.1 0.42 10.8 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Ribosomal_L32p PF01783.23 KPA45442.1 - 1.9e-13 50.4 7.3 2.4e-13 50.1 7.3 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family DNA_pol_delta_4 PF04081.13 KPA45443.1 - 3.2e-45 153.7 2.2 5.5e-45 152.9 2.2 1.5 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 BORA_N PF15280.6 KPA45443.1 - 0.0014 18.3 2.3 0.002 17.9 2.3 1.2 1 0 0 1 1 1 1 Protein aurora borealis N-terminus DUF2981 PF11200.8 KPA45443.1 - 1.3 8.7 4.8 1.7 8.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Q_salvage PF10343.9 KPA45444.1 - 1.1e-130 435.2 0.1 1.5e-130 434.9 0.1 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family ThiF PF00899.21 KPA45445.1 - 2e-71 240.2 0.0 4.4e-71 239.1 0.0 1.5 2 0 0 2 2 2 1 ThiF family UAE_UbL PF14732.6 KPA45445.1 - 5e-21 75.1 3.7 5.3e-21 75.0 1.5 2.2 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KPA45445.1 - 2.1e-05 24.6 9.9 5.4e-05 23.2 0.5 3.4 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KPA45445.1 - 0.0066 16.9 0.1 0.04 14.4 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KPA45445.1 - 0.068 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KPA45445.1 - 0.17 12.2 0.7 1.3 9.3 0.7 2.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 KPA45446.1 - 2e-43 148.6 0.1 3.2e-42 144.7 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA45446.1 - 3.8e-36 124.4 0.4 5.4e-35 120.6 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA45446.1 - 1.3e-09 38.2 0.1 2.1e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA45446.1 - 2.2e-07 30.6 0.0 5.8e-07 29.2 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 KPA45446.1 - 0.039 13.8 0.0 0.065 13.1 0.0 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_7 PF13241.6 KPA45446.1 - 0.07 13.6 0.0 0.13 12.7 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KPA45446.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KPA45446.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PAP2 PF01569.21 KPA45447.1 - 2.4e-19 69.5 2.5 1.1e-18 67.3 2.5 2.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KPA45447.1 - 0.00011 21.9 3.0 0.00036 20.3 3.0 2.0 1 0 0 1 1 1 1 PAP2 superfamily Rep_fac_C PF08542.11 KPA45448.1 - 3e-16 59.6 0.0 7.3e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KPA45448.1 - 4.8e-16 59.4 0.0 1e-15 58.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KPA45448.1 - 4.5e-12 46.0 0.0 1.8e-11 44.1 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KPA45448.1 - 1.8e-09 37.8 0.0 3.7e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KPA45448.1 - 1.7e-07 31.5 0.1 6.6e-07 29.6 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_30 PF13604.6 KPA45448.1 - 9.1e-07 28.8 0.1 2.1e-06 27.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 KPA45448.1 - 1.4e-06 28.3 0.2 0.00014 21.7 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPA45448.1 - 7.1e-06 26.3 0.0 2.8e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KPA45448.1 - 1.1e-05 25.4 0.2 0.0001 22.3 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPA45448.1 - 1.3e-05 25.7 0.0 0.00017 22.0 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 KPA45448.1 - 3e-05 23.9 0.0 6.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 KPA45448.1 - 6e-05 22.8 0.3 0.00022 21.0 0.0 2.1 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KPA45448.1 - 9.8e-05 22.2 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KPA45448.1 - 0.00014 21.1 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KPA45448.1 - 0.00036 20.6 0.0 0.0011 19.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 KPA45448.1 - 0.00046 20.0 0.1 0.0019 18.1 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KPA45448.1 - 0.00046 20.5 0.1 0.0012 19.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KPA45448.1 - 0.0018 18.3 0.0 0.051 13.6 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KPA45448.1 - 0.0039 16.7 0.5 1.3 8.4 0.0 2.4 1 1 0 2 2 2 1 PhoH-like protein TniB PF05621.11 KPA45448.1 - 0.0084 15.5 0.1 0.061 12.7 0.1 2.1 1 1 0 1 1 1 1 Bacterial TniB protein Sigma54_activat PF00158.26 KPA45448.1 - 0.0099 15.6 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 KPA45448.1 - 0.013 16.1 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KPA45448.1 - 0.013 15.8 0.0 0.03 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KPA45448.1 - 0.013 15.3 0.1 0.091 12.5 0.0 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 KPA45448.1 - 0.025 14.0 0.2 0.15 11.4 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KPA45448.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KPA45448.1 - 0.041 14.3 0.0 0.12 12.7 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KPA45448.1 - 0.053 13.1 0.0 0.2 11.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain TK PF00265.18 KPA45448.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase HEAT_2 PF13646.6 KPA45448.1 - 0.079 13.4 0.7 0.73 10.3 0.2 2.5 2 0 0 2 2 2 0 HEAT repeats DUF2075 PF09848.9 KPA45448.1 - 0.089 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 KPA45448.1 - 0.096 12.4 0.0 0.47 10.2 0.0 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein HrpB4 PF09502.10 KPA45448.1 - 0.12 12.2 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) BTB_2 PF02214.22 KPA45449.1 - 2.2e-09 37.5 0.2 6.9e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 KPA45449.1 - 0.11 12.7 0.1 1.7 8.9 0.0 2.3 2 1 0 2 2 2 0 BTB/POZ domain DUF4191 PF13829.6 KPA45450.1 - 0.008 15.5 1.0 0.016 14.5 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) Cyt-b5 PF00173.28 KPA45451.1 - 4e-10 39.7 0.0 6.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Phage_P2_GpE PF06528.12 KPA45451.1 - 0.053 13.1 0.4 0.053 13.1 0.4 1.8 2 0 0 2 2 2 0 Phage P2 GpE Cu_bind_like PF02298.17 KPA45452.1 - 0.11 12.5 0.3 0.66 10.0 0.3 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain SDA1 PF05285.12 KPA45452.1 - 2.6 7.4 4.8 3.2 7.1 4.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KPA45452.1 - 7.1 4.7 5.6 9.2 4.3 5.6 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-X PF09415.10 KPA45453.1 - 2e-22 79.3 0.3 3.7e-22 78.4 0.3 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Mito_carr PF00153.27 KPA45454.1 - 8.9e-68 224.3 5.4 1e-23 83.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 KPA45454.1 - 0.049 13.4 0.8 0.18 11.6 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Ribosomal_S25 PF03297.15 KPA45455.1 - 5.3e-37 126.1 5.3 7e-37 125.7 5.3 1.1 1 0 0 1 1 1 1 S25 ribosomal protein Rrf2 PF02082.20 KPA45455.1 - 0.029 14.7 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator Ribosomal_S7 PF00177.21 KPA45456.1 - 2.8e-38 130.9 1.3 3.8e-38 130.5 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Acetyltransf_1 PF00583.25 KPA45457.1 - 0.00024 21.3 0.1 0.00083 19.6 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 KPA45457.1 - 0.0016 19.1 0.1 0.38 11.5 0.1 2.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPA45457.1 - 0.0032 17.4 0.0 0.45 10.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA45457.1 - 0.021 15.2 0.0 0.067 13.6 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA45457.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NPP1 PF05630.11 KPA45458.1 - 2.3e-63 213.9 0.0 2.7e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DOCK_N PF16172.5 KPA45459.1 - 7.2e-121 403.6 0.0 1.1e-120 403.0 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KPA45459.1 - 1.9e-36 125.8 0.2 2.7e-35 122.0 0.2 2.2 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KPA45459.1 - 5.6e-33 114.4 0.0 9.9e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 KPA45459.1 - 5.4e-05 22.7 0.0 0.00014 21.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPA45459.1 - 0.004 17.0 0.0 0.025 14.4 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KPA45459.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Atg14 PF10186.9 KPA45460.1 - 0.0012 18.0 6.7 0.0025 16.9 6.7 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 KPA45460.1 - 0.0027 15.8 2.2 0.0041 15.2 2.2 1.2 1 0 0 1 1 1 1 Prominin LUC7 PF03194.15 KPA45460.1 - 0.0034 17.1 4.8 0.0075 16.0 4.8 1.6 1 0 0 1 1 1 1 LUC7 N_terminus V_ATPase_I PF01496.19 KPA45460.1 - 0.0067 14.4 5.1 0.0087 14.0 5.1 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Apolipoprotein PF01442.18 KPA45460.1 - 0.0074 16.2 14.8 0.049 13.5 14.8 2.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain HOOK PF05622.12 KPA45460.1 - 0.0078 14.4 9.4 0.011 13.9 9.4 1.2 1 0 0 1 1 1 1 HOOK protein GIT_CC PF16559.5 KPA45460.1 - 0.0082 16.0 6.5 0.53 10.2 1.1 2.7 2 1 0 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor Tropomyosin PF00261.20 KPA45460.1 - 0.012 15.0 8.4 0.024 14.0 8.4 1.5 1 0 0 1 1 1 0 Tropomyosin Hemagglutinin PF00509.18 KPA45460.1 - 0.016 13.7 0.3 0.024 13.1 0.3 1.2 1 0 0 1 1 1 0 Haemagglutinin LMBR1 PF04791.16 KPA45460.1 - 0.018 14.0 1.2 0.024 13.6 1.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 KPA45460.1 - 0.034 13.0 11.0 0.06 12.2 11.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4510 PF14971.6 KPA45460.1 - 0.039 14.3 2.0 17 5.7 0.0 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4510) CLZ PF16526.5 KPA45460.1 - 0.071 13.5 7.5 1.7 9.0 7.5 2.6 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GAS PF13851.6 KPA45460.1 - 0.076 12.4 18.1 0.033 13.5 6.1 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ATPase PF06745.13 KPA45460.1 - 0.089 12.1 1.2 0.15 11.4 1.2 1.3 1 0 0 1 1 1 0 KaiC Occludin_ELL PF07303.13 KPA45460.1 - 0.1 13.3 6.3 1.2 9.9 0.6 3.2 3 0 0 3 3 2 0 Occludin homology domain Exonuc_VII_L PF02601.15 KPA45460.1 - 0.13 11.9 3.4 0.23 11.0 3.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF724 PF05266.14 KPA45460.1 - 0.23 11.3 9.8 0.83 9.4 4.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF2968 PF11180.8 KPA45460.1 - 0.24 11.0 10.3 7.1 6.2 10.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) bZIP_1 PF00170.21 KPA45460.1 - 0.24 11.5 10.7 0.087 12.9 0.6 3.4 1 1 1 2 2 2 0 bZIP transcription factor ZapB PF06005.12 KPA45460.1 - 0.24 11.9 16.9 12 6.4 8.6 3.1 1 1 1 2 2 2 0 Cell division protein ZapB YtxH PF12732.7 KPA45460.1 - 0.27 11.8 3.6 6.9 7.3 1.8 2.8 1 1 1 2 2 2 0 YtxH-like protein Syntaxin PF00804.25 KPA45460.1 - 0.3 10.7 14.2 0.019 14.6 8.8 1.8 2 1 0 2 2 1 0 Syntaxin Syntaxin_2 PF14523.6 KPA45460.1 - 0.32 11.4 11.3 2.8 8.4 11.3 2.5 1 1 0 1 1 1 0 Syntaxin-like protein FlxA PF14282.6 KPA45460.1 - 0.35 10.9 13.8 5.2 7.1 7.1 2.7 1 1 1 2 2 2 0 FlxA-like protein Jnk-SapK_ap_N PF09744.9 KPA45460.1 - 0.35 11.1 16.5 4.9 7.4 16.5 2.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Tektin PF03148.14 KPA45460.1 - 0.36 9.5 14.5 0.67 8.6 14.5 1.3 1 0 0 1 1 1 0 Tektin family SPOUT_MTase PF02590.17 KPA45460.1 - 0.36 10.8 2.2 1.7 8.6 2.2 2.2 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Cnn_1N PF07989.11 KPA45460.1 - 0.4 10.9 12.5 3.2 8.0 1.2 3.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Fib_alpha PF08702.10 KPA45460.1 - 0.4 10.8 9.2 0.44 10.7 7.5 2.0 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family SHE3 PF17078.5 KPA45460.1 - 0.43 10.3 14.9 0.49 10.1 7.4 2.1 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 MCC-bdg_PDZ PF10506.9 KPA45460.1 - 0.46 10.5 6.0 0.41 10.7 2.2 2.5 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CENP-F_leu_zip PF10473.9 KPA45460.1 - 0.56 10.2 15.7 5.7 7.0 5.9 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HlyD_2 PF12700.7 KPA45460.1 - 0.78 8.4 5.2 1.2 7.7 5.2 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Bacillus_HBL PF05791.11 KPA45460.1 - 0.85 9.4 7.0 0.54 10.1 4.5 2.0 2 0 0 2 2 1 0 Bacillus haemolytic enterotoxin (HBL) Troponin PF00992.20 KPA45460.1 - 0.88 9.9 9.9 1.7 8.9 6.6 2.4 1 1 1 2 2 2 0 Troponin FAM76 PF16046.5 KPA45460.1 - 0.94 8.8 18.2 3.5 6.9 18.2 1.8 1 1 0 1 1 1 0 FAM76 protein MerR-DNA-bind PF09278.11 KPA45460.1 - 0.94 10.1 4.2 0.84 10.2 0.2 2.8 3 0 0 3 3 2 0 MerR, DNA binding HAUS-augmin3 PF14932.6 KPA45460.1 - 1.2 8.7 16.3 0.079 12.5 6.0 2.4 2 1 1 3 3 2 0 HAUS augmin-like complex subunit 3 Csm1_N PF18504.1 KPA45460.1 - 1.2 9.5 12.8 1.3 9.4 4.0 3.1 1 1 1 2 2 2 0 Csm1 N-terminal domain Baculo_PEP_C PF04513.12 KPA45460.1 - 1.2 9.1 7.2 3.9 7.5 6.9 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 KPA45460.1 - 1.4 9.0 17.7 1.2 9.2 13.7 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein WXG100 PF06013.12 KPA45460.1 - 1.5 9.1 6.9 4.1 7.7 0.3 3.8 3 1 1 4 4 4 0 Proteins of 100 residues with WXG bZIP_2 PF07716.15 KPA45460.1 - 1.9 8.7 13.8 1.3 9.1 0.7 3.2 3 0 0 3 3 2 0 Basic region leucine zipper DivIVA PF05103.13 KPA45460.1 - 2.2 8.4 9.2 1.1 9.3 1.8 2.8 1 1 2 3 3 3 0 DivIVA protein DUF5082 PF16888.5 KPA45460.1 - 2.2 8.6 11.0 0.44 10.8 1.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) FapA PF03961.13 KPA45460.1 - 2.2 6.8 6.3 3.5 6.1 6.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A APC_N_CC PF16689.5 KPA45460.1 - 2.5 8.2 13.3 0.14 12.3 0.5 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Mto2_bdg PF12808.7 KPA45460.1 - 2.7 8.3 9.2 0.67 10.3 2.9 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4407 PF14362.6 KPA45460.1 - 2.8 7.2 6.3 4.9 6.4 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 KPA45460.1 - 3.2 8.5 6.6 7.4 7.3 4.2 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.11 KPA45460.1 - 3.3 8.0 4.7 39 4.6 2.6 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-H PF05837.12 KPA45460.1 - 3.3 8.1 13.0 4.4 7.8 0.5 2.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF4304 PF14137.6 KPA45460.1 - 3.4 7.8 6.4 33 4.7 2.3 3.6 3 1 0 3 3 2 0 Domain of unknown function (DUF4304) Med9 PF07544.13 KPA45460.1 - 3.6 7.7 8.7 6.9 6.8 6.9 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.20 KPA45460.1 - 4.3 7.3 12.7 4.5 7.3 3.6 2.7 1 1 1 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 KPA45460.1 - 4.4 7.4 7.3 6.7 6.8 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ax_dynein_light PF10211.9 KPA45460.1 - 4.6 7.1 13.4 4.4 7.2 1.6 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain DUF5383 PF17355.2 KPA45460.1 - 5.8 7.3 8.5 23 5.4 6.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5383) YabA PF06156.13 KPA45460.1 - 5.8 7.6 10.8 7.2 7.3 4.0 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Nup54 PF13874.6 KPA45460.1 - 5.8 7.0 9.8 27 4.8 9.8 2.2 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 XhlA PF10779.9 KPA45460.1 - 6 7.1 9.6 5 7.4 2.8 2.5 1 1 1 2 2 2 0 Haemolysin XhlA Swi5 PF07061.11 KPA45460.1 - 6.4 6.9 8.4 29 4.8 0.3 2.8 1 1 1 2 2 2 0 Swi5 JIP_LZII PF16471.5 KPA45460.1 - 6.6 7.0 14.3 2.7 8.2 0.9 2.9 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II UPF0184 PF03670.13 KPA45460.1 - 6.9 7.1 8.8 3.6 8.0 4.7 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) DUF3450 PF11932.8 KPA45460.1 - 8.2 5.7 15.0 8.7 5.6 7.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 KPA45460.1 - 8.8 6.5 19.9 0.24 11.6 12.4 2.2 2 0 0 2 2 1 0 Autophagy protein 16 (ATG16) HSP70 PF00012.20 KPA45461.1 - 1.9e-13 49.5 0.0 3.6e-11 42.0 0.0 2.3 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KPA45461.1 - 0.0018 17.2 0.1 0.041 12.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Peptidase_M22 PF00814.25 KPA45461.1 - 0.039 13.6 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family MUG113 PF13455.6 KPA45461.1 - 0.057 14.1 0.1 0.67 10.7 0.0 2.5 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 IBR PF01485.21 KPA45462.1 - 2.6e-20 72.4 22.1 7.4e-11 42.1 4.1 3.1 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Spt5_N PF11942.8 KPA45462.1 - 4.8 8.2 20.5 3.1 8.8 9.4 3.1 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Borrelia_P83 PF05262.11 KPA45462.1 - 5.5 5.4 9.1 8.6 4.7 9.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein ABC_membrane_2 PF06472.15 KPA45463.1 - 1.7e-104 349.0 0.3 2.6e-104 348.4 0.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KPA45463.1 - 3.8e-17 63.1 0.0 8.7e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KPA45463.1 - 0.00031 20.7 0.0 0.00073 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KPA45463.1 - 0.047 14.2 0.2 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KPA45463.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KPA45463.1 - 0.092 12.2 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KPA45463.1 - 0.1 13.0 2.4 0.54 10.6 0.1 2.6 3 0 0 3 3 3 0 AAA ATPase domain RuvB_N PF05496.12 KPA45463.1 - 0.11 12.3 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KPA45463.1 - 0.13 11.6 0.1 0.61 9.4 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KPA45463.1 - 0.17 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KPA45463.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain zf-CSL PF05207.13 KPA45464.1 - 1.3e-21 76.0 0.7 1.6e-21 75.8 0.7 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KPA45464.1 - 0.0033 17.5 0.3 0.0048 17.0 0.3 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Prok-RING_1 PF14446.6 KPA45464.1 - 0.25 11.3 2.1 0.46 10.4 2.1 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Serglycin PF04360.12 KPA45465.1 - 0.0096 15.9 5.2 0.012 15.6 5.2 1.2 1 0 0 1 1 1 1 Serglycin tRNA-synt_1 PF00133.22 KPA45466.1 - 4.7e-41 140.7 0.1 1.3e-29 103.0 0.0 3.0 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KPA45466.1 - 1.5e-15 56.9 0.7 9.6e-09 34.5 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KPA45466.1 - 1e-12 48.3 2.4 2.1e-12 47.2 1.0 2.3 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KPA45466.1 - 9.8e-09 35.0 0.1 2.9e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Clat_adaptor_s PF01217.20 KPA45468.1 - 1.9e-43 147.8 0.0 3.6e-43 146.9 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.16 KPA45469.1 - 2.2e-36 124.2 0.0 3e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Glyco_hydro38C2 PF17677.1 KPA45469.1 - 0.052 13.7 0.2 0.16 12.1 0.1 1.7 1 1 1 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Complex1_LYR PF05347.15 KPA45470.1 - 0.012 15.6 1.7 0.012 15.6 1.7 2.2 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KPA45470.1 - 0.1 13.4 3.4 0.14 12.9 3.2 1.5 1 1 0 1 1 1 0 Complex1_LYR-like Sugar_tr PF00083.24 KPA45471.1 - 1.3e-105 353.8 14.0 1.6e-105 353.6 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA45471.1 - 1.1e-28 100.2 48.2 2.4e-26 92.5 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA45471.1 - 9.9e-11 40.8 21.6 8.9e-07 27.8 7.0 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.13 KPA45471.1 - 0.0064 15.0 3.5 0.094 11.1 0.2 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector TB2_DP1_HVA22 PF03134.19 KPA45471.1 - 3.2 7.8 7.0 0.34 10.9 1.7 2.1 2 0 0 2 2 2 0 TB2/DP1, HVA22 family Chs7 PF12271.8 KPA45472.1 - 9.9e-117 389.4 3.7 1.1e-116 389.2 3.7 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Trp_oprn_chp PF09534.10 KPA45472.1 - 2.5 7.9 4.2 32 4.3 0.2 2.8 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ssl1 PF04056.14 KPA45473.1 - 7.6e-74 247.7 0.0 1e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KPA45473.1 - 4.3e-19 68.5 7.2 4.3e-19 68.5 7.2 2.4 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KPA45473.1 - 1.6e-16 60.8 0.0 3.5e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KPA45473.1 - 0.00012 22.4 0.0 0.00017 21.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyoxalase PF00903.25 KPA45474.1 - 1.2e-22 80.5 0.1 1.2e-15 57.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KPA45474.1 - 1.8e-11 44.3 0.1 0.0001 22.5 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KPA45474.1 - 0.00012 22.3 0.0 0.046 13.8 0.0 3.0 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KPA45474.1 - 0.0069 16.6 0.0 0.021 15.0 0.0 1.8 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Cadherin_5 PF17892.1 KPA45474.1 - 0.18 11.8 0.5 3.1 7.9 0.1 2.3 2 0 0 2 2 2 0 Cadherin-like domain GIT1_C PF12205.8 KPA45475.1 - 0.023 14.8 0.1 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Ribosomal_L27e PF01777.18 KPA45476.1 - 6e-37 125.9 4.7 9e-37 125.3 4.7 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KPA45476.1 - 0.011 15.7 1.9 0.017 15.1 0.9 1.9 2 0 0 2 2 2 0 KOW motif TPT PF03151.16 KPA45477.1 - 1.3e-24 87.1 24.4 1.5e-24 86.8 24.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KPA45477.1 - 0.0033 17.6 37.9 0.023 14.8 15.2 2.6 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 KPA45477.1 - 0.0082 15.4 25.4 0.014 14.6 25.4 1.3 1 0 0 1 1 1 1 UAA transporter family Amino_oxidase PF01593.24 KPA45478.1 - 3e-07 30.1 0.0 7.3e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPA45478.1 - 4.9e-06 26.7 0.1 1e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPA45478.1 - 0.095 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KPA45478.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain RAC_head PF16717.5 KPA45478.1 - 0.16 12.9 0.1 0.34 11.9 0.1 1.5 1 0 0 1 1 1 0 Ribosome-associated complex head domain Pyr_redox_2 PF07992.14 KPA45478.1 - 0.19 10.9 0.1 0.69 9.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA45478.1 - 0.22 10.7 0.1 0.33 10.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HATPase_c PF02518.26 KPA45479.1 - 4.6e-31 107.6 0.0 1.2e-30 106.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPA45479.1 - 1.9e-21 76.3 0.1 8.8e-21 74.2 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KPA45479.1 - 5.7e-18 64.7 0.7 3.1e-17 62.4 0.5 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KPA45479.1 - 3.8e-12 46.7 0.0 1.4e-11 44.9 0.0 2.0 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.6 KPA45479.1 - 1.3e-10 42.0 0.9 1e-09 39.0 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Pkinase PF00069.25 KPA45479.1 - 4.8e-07 29.4 0.0 1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 KPA45479.1 - 1.4e-06 28.9 0.0 4.7e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 KPA45479.1 - 0.001 18.9 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 KPA45479.1 - 0.018 15.4 0.0 0.045 14.1 0.0 1.7 1 0 0 1 1 1 0 GAF domain TPR_12 PF13424.6 KPA45479.1 - 0.024 14.9 7.1 0.92 9.8 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NB-ARC PF00931.22 KPA45479.1 - 0.036 13.2 0.1 0.52 9.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 KPA45479.1 - 0.078 12.9 0.2 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TPR_1 PF00515.28 KPA45479.1 - 9.5 6.2 7.3 11 6.1 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2722 PF10846.8 KPA45480.1 - 2.2e-08 33.5 10.3 2.9e-07 29.8 0.0 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 KPA45480.1 - 0.74 9.7 23.9 0.13 12.3 6.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RabGAP-TBC PF00566.18 KPA45481.1 - 3.6e-34 118.3 0.0 5.1e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DIL PF01843.19 KPA45483.1 - 1.2e-31 109.1 0.6 2.4e-31 108.1 0.6 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KPA45483.1 - 1.2e-15 57.8 0.2 1.8e-09 38.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA45483.1 - 1.2e-11 44.9 0.0 4.1e-09 36.8 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPA45483.1 - 4.5e-10 39.6 0.0 3.4e-06 27.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KPA45483.1 - 4.5e-10 39.5 0.1 0.00092 19.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KPA45483.1 - 8.7e-09 34.9 0.0 0.18 12.4 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Allantoicase PF03561.15 KPA45484.1 - 3.3e-91 302.8 0.1 2.3e-45 154.1 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Cytochrom_B561 PF03188.16 KPA45485.1 - 2.6e-19 69.7 4.9 5e-19 68.8 4.9 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KPA45485.1 - 0.044 13.9 17.8 5 7.3 3.7 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) COX15-CtaA PF02628.15 KPA45485.1 - 0.17 10.9 11.2 1.1 8.2 11.2 2.2 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein DUF4006 PF13179.6 KPA45485.1 - 0.34 10.8 7.4 1 9.4 0.1 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF4006) SLATT_3 PF18184.1 KPA45485.1 - 0.38 10.9 2.6 0.58 10.3 0.1 2.1 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 DUF716 PF04819.12 KPA45485.1 - 3.1 7.4 10.5 0.1 12.2 1.3 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF716) HATPase_c PF02518.26 KPA45486.1 - 4.5e-26 91.6 0.3 9.4e-26 90.5 0.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 KPA45486.1 - 8.1e-22 77.3 2.1 1.4e-11 44.5 0.3 4.9 4 0 0 4 4 4 3 PAS fold Response_reg PF00072.24 KPA45486.1 - 2.5e-20 72.7 0.0 8.2e-20 71.1 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KPA45486.1 - 1.7e-18 66.4 0.0 4.3e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KPA45486.1 - 1.1e-07 32.1 0.0 0.014 15.6 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KPA45486.1 - 1.6e-07 31.6 0.0 2.2e-05 24.6 0.0 2.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KPA45486.1 - 2.1e-06 27.7 0.0 0.091 12.8 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KPA45486.1 - 0.005 16.8 0.0 0.5 10.5 0.0 2.6 2 0 0 2 2 2 1 PAS domain His_Phos_1 PF00300.22 KPA45488.1 - 1e-28 100.3 0.0 2.1e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1168 PF06658.12 KPA45489.1 - 1e-38 132.2 13.1 1.5e-38 131.6 13.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF5401 PF17380.2 KPA45489.1 - 0.65 8.0 12.3 0.89 7.6 12.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Cpn60_TCP1 PF00118.24 KPA45490.1 - 1.6e-172 574.6 1.3 1.8e-172 574.4 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 KPA45490.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 BRK domain UPF0029 PF01205.19 KPA45491.1 - 1.4e-31 109.0 0.0 1.8e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 GMC_oxred_N PF00732.19 KPA45494.1 - 6.2e-26 91.5 0.0 1.2e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA45494.1 - 4.5e-18 66.2 0.1 1e-17 65.0 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPA45494.1 - 8.4e-06 25.1 0.5 0.0002 20.6 0.2 2.4 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KPA45494.1 - 8.4e-05 22.7 0.1 0.00022 21.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPA45494.1 - 0.00046 19.0 0.3 0.00084 18.1 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KPA45494.1 - 0.0026 17.0 0.2 0.0062 15.8 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA45494.1 - 0.0034 17.0 0.1 0.029 14.0 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 KPA45494.1 - 0.0042 16.7 0.1 0.0088 15.7 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KPA45494.1 - 0.0065 15.6 0.0 0.0095 15.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KPA45494.1 - 0.014 15.9 0.2 0.036 14.6 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA45494.1 - 0.017 14.4 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KPA45494.1 - 0.027 13.7 0.1 0.041 13.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 KPA45494.1 - 0.16 11.3 0.5 0.24 10.6 0.5 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KPA45494.1 - 0.19 11.0 1.7 0.63 9.3 1.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Selenoprotein_S PF06936.11 KPA45495.1 - 0.051 13.4 0.9 0.072 12.9 0.9 1.3 1 1 0 1 1 1 0 Selenoprotein S (SelS) Voldacs PF03517.13 KPA45496.1 - 2.2e-20 73.2 1.1 2.2e-20 73.2 1.1 2.0 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling EFTUD2 PF16004.5 KPA45496.1 - 1.1 9.8 8.2 0.13 12.8 2.4 2.2 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF1996 PF09362.10 KPA45498.1 - 1.2e-83 280.8 0.2 1.6e-83 280.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TPR_2 PF07719.17 KPA45499.1 - 5.5e-07 29.2 0.0 0.28 11.4 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KPA45499.1 - 6e-06 25.9 0.7 0.022 14.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPA45499.1 - 3.5e-05 24.0 0.2 0.00051 20.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat UBA PF00627.31 KPA45499.1 - 6.5e-05 22.7 0.1 0.00015 21.6 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain TPR_16 PF13432.6 KPA45499.1 - 0.016 15.8 0.5 0.19 12.4 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 KPA45499.1 - 0.088 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain TPR_19 PF14559.6 KPA45499.1 - 0.11 13.0 2.4 0.36 11.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat UQ_con PF00179.26 KPA45500.1 - 2.4e-50 169.8 0.0 2.7e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPA45500.1 - 0.046 13.4 0.0 0.088 12.5 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B MS_channel PF00924.18 KPA45502.1 - 1.9e-20 73.3 2.2 3.1e-20 72.6 2.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KPA45502.1 - 6.4e-05 22.2 1.3 0.00019 20.7 1.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KPA45502.1 - 0.00023 20.8 0.1 0.00071 19.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KPA45502.1 - 0.00041 19.7 0.2 0.0011 18.3 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KPA45502.1 - 0.0032 17.9 0.1 0.01 16.2 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair DUF4181 PF13789.6 KPA45502.1 - 0.0073 16.6 5.6 0.9 9.8 0.8 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4181) DUF2985 PF11204.8 KPA45502.1 - 3.2 8.0 9.8 0.043 14.0 0.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) Glyco_hydro_31 PF01055.26 KPA45503.1 - 1.3e-139 466.2 4.9 1.7e-139 465.8 4.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KPA45503.1 - 1.7e-24 85.9 0.7 7.3e-24 83.9 0.2 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KPA45503.1 - 1e-06 28.9 0.5 3.8e-06 27.1 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NDK PF00334.19 KPA45504.1 - 2.2e-53 179.9 0.0 2.8e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.9 KPA45505.1 - 4.2e-32 110.4 0.0 1.1e-31 109.1 0.0 1.7 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KPA45505.1 - 0.0046 17.5 0.2 0.007 16.9 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Glyco_hydro_18 PF00704.28 KPA45507.1 - 4.9e-14 52.8 0.0 6.4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RTA1 PF04479.13 KPA45508.1 - 3.8e-57 193.2 8.3 3.8e-57 193.2 8.3 1.4 2 0 0 2 2 2 1 RTA1 like protein Tetraspanin PF00335.20 KPA45508.1 - 1.8 8.2 9.2 0.29 10.8 4.5 2.0 1 1 1 2 2 2 0 Tetraspanin family DUF4140 PF13600.6 KPA45509.1 - 0.08 13.4 0.1 0.08 13.4 0.1 3.6 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 KPA45509.1 - 0.086 12.9 11.7 0.59 10.2 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF3452 PF11934.8 KPA45509.1 - 0.12 12.0 1.1 0.21 11.1 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3452) DUF745 PF05335.13 KPA45509.1 - 0.16 11.6 22.4 0.049 13.4 2.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF745) CREPT PF16566.5 KPA45509.1 - 0.62 10.2 20.6 1.9 8.7 2.5 4.0 4 0 0 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour Glyco_hydro38C2 PF17677.1 KPA45510.1 - 0.097 12.8 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain LSM PF01423.22 KPA45511.1 - 2.6e-15 55.9 0.2 4e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 LSM domain GCD14 PF08704.10 KPA45512.1 - 1.8e-64 217.8 0.7 1.8e-64 217.8 0.7 3.1 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Mycoplasma_p37 PF06646.11 KPA45512.1 - 0.04 13.2 0.3 0.072 12.3 0.3 1.3 1 0 0 1 1 1 0 High affinity transport system protein p37 tRNA-synt_1e PF01406.19 KPA45513.1 - 1.6e-114 382.3 0.0 2.5e-114 381.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 KPA45513.1 - 2.2e-06 28.1 0.1 7.7e-06 26.3 0.1 2.0 1 0 0 1 1 1 1 DALR domain tRNA-synt_1g PF09334.11 KPA45513.1 - 3.7e-06 26.0 0.1 0.038 12.7 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 KPA45513.1 - 0.12 11.2 2.2 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Apolipoprotein PF01442.18 KPA45514.1 - 2.1e-05 24.5 14.6 0.016 15.1 0.2 3.2 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain VirB8 PF04335.13 KPA45514.1 - 0.025 14.4 0.2 0.047 13.5 0.2 1.4 1 0 0 1 1 1 0 VirB8 protein ApoO PF09769.9 KPA45514.1 - 0.029 14.3 0.6 25 4.8 0.3 3.7 3 0 0 3 3 3 0 Apolipoprotein O Phasin_2 PF09361.10 KPA45514.1 - 0.038 14.3 12.4 3.2 8.1 0.3 5.1 5 2 0 5 5 5 0 Phasin protein Trans_reg_C PF00486.28 KPA45514.1 - 0.062 13.4 0.4 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal DUF883 PF05957.13 KPA45514.1 - 0.43 11.2 20.0 3.8 8.2 4.5 5.6 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) GAT PF03127.14 KPA45514.1 - 0.7 10.3 3.8 1.2 9.5 1.5 2.6 3 0 0 3 3 3 0 GAT domain CinA_KH PF18146.1 KPA45514.1 - 0.75 10.0 4.0 30 4.8 0.1 4.2 5 0 0 5 5 5 0 Damage-inducible protein CinA KH domain Peptidase_M41 PF01434.18 KPA45514.1 - 1 9.2 7.3 0.65 9.8 1.1 2.9 1 1 1 3 3 3 0 Peptidase family M41 PRESAN PF09687.10 KPA45514.1 - 7.9 7.1 8.9 2 9.0 0.0 3.5 3 2 0 3 3 3 0 Plasmodium RESA N-terminal p450 PF00067.22 KPA45516.1 - 1.3e-21 76.9 0.0 2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2293 PF10056.9 KPA45517.1 - 3e-34 117.1 1.0 7.8e-34 115.8 1.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) TatD_DNase PF01026.21 KPA45517.1 - 0.042 13.2 0.1 0.071 12.5 0.1 1.2 1 0 0 1 1 1 0 TatD related DNase NUC173 PF08161.12 KPA45518.1 - 9.3e-80 267.1 0.1 2e-77 259.5 0.0 3.2 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.22 KPA45518.1 - 0.049 13.9 3.1 2.6 8.5 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat HHA PF05321.11 KPA45518.1 - 0.09 13.1 0.0 1.2 9.5 0.0 2.8 2 0 0 2 2 2 0 Haemolysin expression modulating protein HEAT_2 PF13646.6 KPA45518.1 - 0.16 12.4 3.2 8.5 6.8 0.1 4.3 4 0 0 4 4 4 0 HEAT repeats Metallophos_2 PF12850.7 KPA45519.1 - 4.1e-12 46.6 0.0 5.3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KPA45519.1 - 0.018 15.5 0.0 0.41 11.1 0.0 2.2 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Shugoshin_N PF07558.11 KPA45520.1 - 2.5e-14 52.9 6.2 9.1e-14 51.1 6.2 2.1 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KPA45520.1 - 8.5e-11 41.5 5.8 8.5e-11 41.5 5.8 3.5 2 0 0 2 2 2 1 Shugoshin C terminus Mod_r PF07200.13 KPA45520.1 - 0.1 12.7 1.8 0.25 11.5 1.8 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Fez1 PF06818.15 KPA45520.1 - 4.1 7.8 8.2 7.8 6.9 0.2 2.8 2 0 0 2 2 2 0 Fez1 DASH_Dad2 PF08654.10 KPA45521.1 - 2.8e-33 114.3 1.5 4.5e-33 113.6 1.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.22 KPA45521.1 - 0.013 15.7 0.4 0.013 15.7 0.4 1.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain IFT20 PF14931.6 KPA45521.1 - 0.022 14.9 1.5 0.03 14.5 0.4 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 CEP209_CC5 PF16574.5 KPA45521.1 - 0.046 13.9 1.3 0.076 13.2 1.3 1.5 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 SLX9 PF15341.6 KPA45521.1 - 0.075 13.4 1.1 0.095 13.1 1.1 1.3 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF1664 PF07889.12 KPA45521.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SKG6 PF08693.10 KPA45523.1 - 5.2e-07 29.0 0.1 1.2e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CcmD PF04995.14 KPA45523.1 - 0.034 14.2 0.6 0.056 13.5 0.6 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4381 PF14316.6 KPA45523.1 - 0.036 14.3 0.1 0.068 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CD34_antigen PF06365.12 KPA45524.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF3149 PF11346.8 KPA45524.1 - 0.2 11.3 0.7 0.36 10.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) HA2 PF04408.23 KPA45525.1 - 5.2e-18 65.3 0.1 1.6e-17 63.7 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KPA45525.1 - 3.1e-14 53.1 0.0 7e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KPA45525.1 - 2.3e-11 44.0 0.0 6e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KPA45525.1 - 5.3e-05 23.5 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPA45525.1 - 0.00023 21.0 0.0 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPA45525.1 - 0.0016 18.8 0.0 0.0041 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KPA45525.1 - 0.0051 16.6 1.0 0.039 13.7 1.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KPA45525.1 - 0.015 14.4 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KPA45525.1 - 0.079 12.4 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 KPA45525.1 - 0.12 11.7 0.3 0.5 9.6 0.1 2.1 1 1 1 2 2 2 0 Zeta toxin cobW PF02492.19 KPA45525.1 - 0.17 11.5 0.2 1.6 8.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KPA45525.1 - 1.9 9.0 5.7 0.29 11.6 1.1 1.9 2 1 0 2 2 2 0 AAA domain CUE PF02845.16 KPA45526.1 - 4.4e-12 45.5 0.0 7.3e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain Ank_2 PF12796.7 KPA45527.1 - 2.9e-29 101.5 2.3 8.5e-09 35.9 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA45527.1 - 1.2e-24 86.4 6.3 1.6e-08 34.9 0.5 6.0 3 1 2 5 5 5 5 Ankyrin repeats (many copies) SPX PF03105.19 KPA45527.1 - 2.1e-21 77.3 16.6 3.4e-09 37.1 1.6 3.2 1 1 2 3 3 3 3 SPX domain Ank_5 PF13857.6 KPA45527.1 - 1.5e-18 66.6 10.2 3.1e-06 27.3 0.0 7.3 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA45527.1 - 1.9e-16 58.5 6.7 0.011 16.2 0.1 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KPA45527.1 - 2.6e-11 43.4 13.6 0.095 13.2 0.1 6.9 5 2 2 7 7 7 4 Ankyrin repeat GDPD PF03009.17 KPA45527.1 - 6.6e-08 32.6 0.0 3.6e-07 30.2 0.0 2.2 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family tRNA-synt_2_TM PF16995.5 KPA45528.1 - 0.052 13.2 0.1 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase Coa1 PF08695.10 KPA45529.1 - 1.8e-41 140.5 0.0 2.3e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L3 PF00297.22 KPA45530.1 - 5.2e-16 58.6 3.4 4.3e-13 49.0 2.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 PITH PF06201.13 KPA45531.1 - 1.3e-43 148.8 0.1 1.6e-43 148.5 0.1 1.1 1 0 0 1 1 1 1 PITH domain Rrn6 PF10214.9 KPA45532.1 - 1.1e-175 586.6 2.8 1.7e-175 586.0 2.8 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 KPA45533.1 - 2.1e-26 91.9 0.7 7.1e-26 90.2 0.1 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Hom_end_hint PF05203.16 KPA45533.1 - 0.14 12.0 3.0 0.26 11.2 3.0 1.5 1 0 0 1 1 1 0 Hom_end-associated Hint Atg14 PF10186.9 KPA45533.1 - 0.22 10.6 7.2 0.37 9.8 7.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 KPA45533.1 - 0.62 7.9 7.5 0.75 7.6 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KPA45533.1 - 0.8 9.7 6.4 3.1 7.9 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KPA45533.1 - 3.6 6.9 10.9 4.9 6.4 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MOZART1 PF12554.8 KPA45534.1 - 8.2e-26 89.5 0.6 9.6e-26 89.3 0.6 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated zinc_ribbon_6 PF14599.6 KPA45535.1 - 3e-25 88.0 0.2 3e-25 88.0 0.2 4.1 4 1 0 4 4 2 1 Zinc-ribbon zf-CHY PF05495.12 KPA45535.1 - 3.5e-19 69.1 21.3 3.5e-19 69.1 21.3 3.8 2 1 1 3 3 2 1 CHY zinc finger zf-RING_2 PF13639.6 KPA45535.1 - 5.9e-08 32.9 10.1 5.9e-08 32.9 10.1 5.7 4 1 2 6 6 5 1 Ring finger domain zf-RING_UBOX PF13445.6 KPA45535.1 - 2.5e-07 30.6 4.8 2.5e-07 30.6 4.8 5.1 5 2 1 6 6 5 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPA45535.1 - 5.3e-07 29.5 7.3 5.3e-07 29.5 7.3 6.1 2 1 2 4 4 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KPA45535.1 - 2.4e-06 27.3 8.3 2.4e-06 27.3 8.3 5.6 2 1 4 6 6 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA45535.1 - 7.4e-06 25.7 7.8 7.4e-06 25.7 7.8 4.7 5 1 1 6 6 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA45535.1 - 1.4e-05 24.9 6.4 1.4e-05 24.9 6.4 5.4 4 2 2 6 6 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPA45535.1 - 0.00064 19.5 8.6 0.00064 19.5 8.6 6.1 3 1 2 5 5 3 1 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 KPA45535.1 - 0.008 16.1 3.5 0.008 16.1 3.5 6.0 6 1 1 7 7 7 1 Prokaryotic RING finger family 1 zf-RING_11 PF17123.5 KPA45535.1 - 0.025 14.3 1.7 0.025 14.3 1.7 5.2 5 0 0 5 5 5 0 RING-like zinc finger Cwf_Cwc_15 PF04889.12 KPA45535.1 - 2.4 7.8 8.4 3.8 7.2 8.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PMT PF02366.18 KPA45536.1 - 4.3e-85 285.2 13.0 4.3e-85 285.2 13.0 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KPA45536.1 - 6.1e-65 218.5 15.3 6.1e-65 218.5 15.3 2.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KPA45536.1 - 7.5e-37 127.0 0.9 1.1e-36 126.4 0.9 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KPA45536.1 - 1.8e-05 25.0 7.3 1.8e-05 25.0 7.3 2.6 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2976 PF11190.8 KPA45536.1 - 0.018 14.8 1.3 0.018 14.8 1.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Ras PF00071.22 KPA45537.1 - 1.4e-50 171.1 0.0 1.7e-39 135.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KPA45537.1 - 4.3e-29 101.2 0.0 1.7e-18 67.0 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA45537.1 - 1.1e-11 44.5 0.0 3.6e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPA45537.1 - 8.8e-07 28.6 0.0 3e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KPA45537.1 - 1.7e-06 27.6 0.0 3.6e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KPA45537.1 - 9.8e-05 22.4 0.0 0.00033 20.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPA45537.1 - 0.0002 21.3 0.2 0.59 10.0 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 KPA45537.1 - 0.025 14.3 0.1 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KPA45537.1 - 0.041 14.2 0.4 1.1 9.6 0.0 2.4 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 KPA45537.1 - 0.23 12.0 1.0 0.7 10.4 1.0 2.0 1 1 0 1 1 1 0 ABC transporter Choline_transpo PF04515.12 KPA45538.1 - 2e-31 109.4 17.1 2e-31 109.4 17.1 2.6 2 2 0 2 2 2 1 Plasma-membrane choline transporter FMN_dh PF01070.18 KPA45540.1 - 1.9e-92 310.0 0.2 5.2e-51 173.7 0.1 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.15 KPA45540.1 - 8.6e-05 22.1 0.4 0.00016 21.2 0.1 1.6 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KPA45540.1 - 0.00012 21.7 0.6 0.068 12.6 0.1 3.1 3 0 0 3 3 3 1 Histidine biosynthesis protein IMPDH PF00478.25 KPA45540.1 - 0.0014 17.7 0.2 0.0036 16.4 0.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KPA45540.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 KPA45540.1 - 0.025 13.8 1.0 0.27 10.4 0.0 2.5 2 1 0 3 3 3 0 Dihydroorotate dehydrogenase ThiG PF05690.14 KPA45540.1 - 0.031 13.6 0.0 0.32 10.3 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Peptidase_M19 PF01244.21 KPA45540.1 - 0.063 12.4 0.1 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) PA PF02225.22 KPA45540.1 - 0.13 12.3 1.7 12 6.1 0.9 2.8 2 1 0 2 2 2 0 PA domain Glyco_transf_28 PF03033.20 KPA45541.1 - 2e-20 73.2 0.2 6.4e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KPA45541.1 - 0.00014 20.8 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KPA45541.1 - 0.00032 21.0 0.1 0.0019 18.5 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KPA45541.1 - 0.0018 18.3 0.1 0.023 14.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain UIM PF02809.20 KPA45541.1 - 0.068 13.1 33.8 0.3 11.1 2.5 5.2 5 0 0 5 5 5 0 Ubiquitin interaction motif SlyX PF04102.12 KPA45542.1 - 2 9.1 4.5 0.42 11.3 0.3 2.0 2 0 0 2 2 2 0 SlyX Sec61_beta PF03911.16 KPA45544.1 - 3e-19 68.8 1.9 4e-19 68.4 1.9 1.2 1 0 0 1 1 1 1 Sec61beta family NIF PF03031.18 KPA45545.1 - 1.4e-54 184.1 0.1 1.9e-54 183.7 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.15 KPA45546.1 - 4.9e-93 311.4 0.3 1.1e-91 307.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KPA45546.1 - 6.8e-15 55.8 0.0 1.7e-14 54.5 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KPA45546.1 - 0.00069 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KPA45546.1 - 0.029 14.9 2.1 1.5 9.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain End3 PF12761.7 KPA45546.1 - 0.057 13.6 0.9 0.13 12.5 0.9 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 RuvB_N PF05496.12 KPA45546.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPA45546.1 - 0.081 13.3 0.1 0.22 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 KPA45546.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 KPA45546.1 - 0.18 12.2 0.0 0.58 10.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 KPA45548.1 - 0.038 13.4 0.0 21 4.4 0.0 3.2 3 0 0 3 3 3 0 Protein kinase domain Pkinase_Tyr PF07714.17 KPA45548.1 - 0.097 11.9 0.1 1.7 7.8 0.0 2.5 3 0 0 3 3 3 0 Protein tyrosine kinase Aldo_ket_red PF00248.21 KPA45549.1 - 5.6e-43 147.2 0.0 7.7e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.7 KPA45550.1 - 7.2e-38 128.0 24.7 1.4e-09 38.0 1.3 6.4 6 0 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPA45550.1 - 3.6e-24 84.3 26.7 1.1e-06 28.3 3.8 5.6 3 2 1 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 KPA45550.1 - 8.9e-20 70.9 25.7 1.8e-08 34.1 1.1 3.6 1 1 4 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 KPA45550.1 - 3.9e-07 29.6 21.4 0.1 12.7 0.5 8.0 9 0 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.33 KPA45550.1 - 0.018 15.5 29.0 11 7.0 0.2 8.8 9 2 0 9 9 9 0 Leucine Rich Repeat Abhydrolase_3 PF07859.13 KPA45551.1 - 0.0031 17.4 0.0 0.0056 16.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA45551.1 - 0.009 15.5 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 KPA45551.1 - 0.18 11.4 0.0 10 5.6 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase BTB PF00651.31 KPA45552.1 - 1.7e-08 34.7 0.1 7.2e-08 32.6 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain PCI PF01399.27 KPA45553.1 - 2.8e-12 47.1 0.0 6.2e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain Ribosomal_L18A PF01775.17 KPA45554.1 - 1.7e-54 183.0 0.1 2.3e-54 182.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Fungal_trans PF04082.18 KPA45555.1 - 3.8e-12 45.8 0.1 7.3e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA45555.1 - 1.7e-09 37.6 9.0 2.9e-09 36.9 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spc7_N PF15402.6 KPA45555.1 - 1 7.5 4.9 1.4 7.1 4.9 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Acetyltransf_3 PF13302.7 KPA45556.1 - 3.3e-23 82.9 0.0 4.9e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1772 PF08592.11 KPA45557.1 - 2.9e-28 98.9 5.9 4.1e-28 98.4 5.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Sm_multidrug_ex PF06695.11 KPA45557.1 - 0.0035 18.0 0.5 0.0069 17.0 0.5 1.6 1 0 0 1 1 1 1 Putative small multi-drug export protein MFS_MOT1 PF16983.5 KPA45557.1 - 0.12 12.8 6.6 0.18 12.2 5.6 1.9 1 1 0 1 1 1 0 Molybdate transporter of MFS superfamily RFX5_DNA_bdg PF14621.6 KPA45558.1 - 0.071 12.9 15.1 0.81 9.4 3.9 2.1 1 1 1 2 2 2 0 RFX5 DNA-binding domain Ric8 PF10165.9 KPA45559.1 - 3.5e-121 405.5 0.0 4e-121 405.3 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.8 KPA45560.1 - 1e-140 469.0 1.8 1.4e-140 468.5 1.8 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal SurA_N PF09312.11 KPA45560.1 - 0.11 12.5 2.4 0.54 10.3 2.4 2.1 1 1 0 1 1 1 0 SurA N-terminal domain Ribosomal_S5 PF00333.20 KPA45561.1 - 2e-27 94.9 1.0 4.9e-27 93.7 1.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KPA45561.1 - 7.9e-23 79.7 0.0 1.3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF1633 PF07794.11 KPA45561.1 - 0.095 10.9 0.1 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) FoP_duplication PF13865.6 KPA45561.1 - 2.3 8.8 14.5 5.4 7.6 14.5 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Rhodanese PF00581.20 KPA45562.1 - 7.4e-18 65.0 0.0 6.7e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain DAP_epimerase PF01678.19 KPA45562.1 - 0.059 13.6 1.6 2.6 8.2 1.6 2.3 1 1 0 1 1 1 0 Diaminopimelate epimerase Hydrolase_like PF13242.6 KPA45562.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like zf-ANAPC11 PF12861.7 KPA45563.1 - 3.5e-45 152.0 12.0 4e-45 151.8 12.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KPA45563.1 - 1e-21 77.0 12.3 1.4e-21 76.5 12.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KPA45563.1 - 1.8e-08 34.6 16.3 4.1e-07 30.2 16.3 2.4 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KPA45563.1 - 6.3e-06 26.1 7.0 5.6e-05 23.1 5.6 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KPA45563.1 - 0.00045 20.0 14.7 0.0018 18.1 14.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPA45563.1 - 0.0011 18.8 8.5 0.0011 18.8 8.5 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KPA45563.1 - 0.0027 17.3 11.8 0.025 14.2 11.8 2.1 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KPA45563.1 - 0.0034 17.1 3.3 0.0034 17.1 3.3 2.3 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KPA45563.1 - 0.0055 16.5 13.3 0.0055 16.5 13.3 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KPA45563.1 - 0.0068 16.6 17.0 0.12 12.6 17.0 3.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Nse PF11789.8 KPA45563.1 - 0.011 15.6 5.0 0.018 14.8 5.0 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KPA45563.1 - 0.013 15.6 12.0 0.016 15.3 9.4 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-HIT PF04438.16 KPA45563.1 - 0.062 13.2 4.8 0.083 12.8 1.0 2.4 2 0 0 2 2 2 0 HIT zinc finger YacG PF03884.14 KPA45563.1 - 0.13 12.0 6.0 0.32 10.8 0.2 2.7 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-RING_11 PF17123.5 KPA45563.1 - 0.14 11.9 12.2 0.64 9.8 9.5 2.9 2 1 0 2 2 2 0 RING-like zinc finger VioE PF18234.1 KPA45563.1 - 0.15 12.2 0.7 0.16 12.1 0.7 1.0 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE zf-RING_5 PF14634.6 KPA45563.1 - 0.22 11.5 17.9 9 6.3 18.4 2.8 1 1 1 2 2 2 0 zinc-RING finger domain Rad50_zn_hook PF04423.14 KPA45563.1 - 0.23 11.3 3.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif UBZ_FAAP20 PF15750.5 KPA45563.1 - 0.24 11.3 6.7 0.75 9.8 0.3 2.8 2 1 1 3 3 3 0 Ubiquitin-binding zinc-finger zf-RING-like PF08746.11 KPA45563.1 - 2.2 8.7 14.2 3 8.2 11.6 2.2 1 1 1 2 2 2 0 RING-like domain RINGv PF12906.7 KPA45563.1 - 2.4 8.3 14.4 2.4 8.3 12.3 2.1 1 1 1 2 2 2 0 RING-variant domain Opy2 PF09463.10 KPA45563.1 - 2.5 8.5 10.7 6.5 7.2 6.3 2.4 2 1 0 2 2 2 0 Opy2 protein DZR PF12773.7 KPA45563.1 - 8.6 6.5 13.0 4.9 7.3 6.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.6 KPA45564.1 - 0.13 13.2 0.4 0.13 13.2 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KPA45564.1 - 0.25 11.7 1.9 0.56 10.6 1.9 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.25 KPA45565.1 - 1.2e-57 195.3 0.0 1.5e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA45565.1 - 8.7e-27 94.0 0.0 1.3e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA45565.1 - 5.3e-08 32.5 0.0 6.9e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KPA45565.1 - 0.0093 15.9 0.0 0.59 10.0 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KPA45565.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 KPA45566.1 - 1.2e-48 164.3 0.0 1.5e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPA45566.1 - 3.8e-05 23.4 0.0 5.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KPA45566.1 - 0.0017 18.6 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KPA45566.1 - 0.0049 16.7 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 UEV domain Ribosomal_L31e PF01198.19 KPA45567.1 - 2.9e-40 136.4 1.6 4.8e-40 135.7 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e RGS PF00615.19 KPA45568.1 - 1.6e-12 47.7 0.0 7.7e-11 42.3 0.0 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain PCI PF01399.27 KPA45569.1 - 3.2e-07 30.8 0.0 5.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 KPA45569.1 - 0.00088 19.1 0.1 0.0021 17.9 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain E1-E2_ATPase PF00122.20 KPA45570.1 - 7.9e-50 168.9 0.1 2.3e-49 167.4 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 KPA45570.1 - 1.4e-46 156.8 0.5 1.4e-11 44.6 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KPA45570.1 - 9.4e-43 146.9 1.9 3.3e-42 145.1 1.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KPA45570.1 - 2.4e-06 27.5 2.1 6.8e-06 26.0 0.8 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L18p PF00861.22 KPA45570.1 - 0.24 11.8 0.6 1.5 9.3 0.0 2.6 3 0 0 3 3 3 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast TPT PF03151.16 KPA45571.1 - 9.7e-34 117.0 15.4 1.2e-33 116.7 15.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KPA45571.1 - 3.2e-07 29.8 18.9 7.1e-07 28.7 18.9 1.5 1 1 0 1 1 1 1 UAA transporter family SLATT_fungal PF18142.1 KPA45571.1 - 0.51 10.3 6.1 0.074 13.0 1.3 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain DUF155 PF02582.14 KPA45572.1 - 1.3e-54 185.0 0.4 2.5e-54 184.1 0.1 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 RasGAP PF00616.19 KPA45573.1 - 1.1e-52 178.7 0.3 3.2e-52 177.3 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KPA45573.1 - 3.1e-48 163.4 5.4 3.1e-48 163.4 5.4 2.7 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 KPA45573.1 - 1.5e-14 52.3 43.3 0.0064 16.2 0.0 14.0 16 0 0 16 16 16 6 IQ calmodulin-binding motif CH PF00307.31 KPA45573.1 - 6e-11 42.5 0.1 3.2e-10 40.1 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain HGD-D PF06050.13 KPA45573.1 - 0.054 13.2 2.0 0.14 11.8 2.0 1.8 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component IL28A PF15177.6 KPA45573.1 - 0.31 10.9 8.0 0.23 11.3 1.6 3.3 2 1 0 2 2 2 0 Interleukin-28A RNase_J_C PF17770.1 KPA45573.1 - 0.32 12.1 1.3 31 5.7 0.0 4.6 4 0 0 4 4 4 0 Ribonuclease J C-terminal domain NPV_P10 PF05531.12 KPA45573.1 - 5.9 7.4 9.1 55 4.3 0.0 4.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Sulfatase PF00884.23 KPA45574.1 - 9e-57 192.8 0.1 1.1e-56 192.4 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KPA45574.1 - 3.4e-25 87.6 0.9 3.4e-25 87.6 0.9 2.2 3 0 0 3 3 3 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KPA45574.1 - 1.4e-08 34.7 0.1 0.00017 21.3 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KPA45574.1 - 5.7e-05 21.9 0.0 8.4e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4994 PF16385.5 KPA45574.1 - 0.01 15.7 0.1 0.52 10.3 0.1 2.4 1 1 0 1 1 1 0 Domain of unknown function DUF4976 PF16347.5 KPA45574.1 - 0.067 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF1501 PF07394.12 KPA45574.1 - 0.18 10.9 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Med8 PF10232.9 KPA45575.1 - 1.4e-32 113.2 6.1 2e-32 112.7 6.1 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 NOA36 PF06524.12 KPA45575.1 - 3.6 6.8 6.0 5.3 6.3 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein GFA PF04828.14 KPA45577.1 - 5.7e-20 71.4 0.9 9.3e-20 70.8 0.9 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNase_P_p30 PF01876.16 KPA45579.1 - 3.1e-56 190.2 0.0 1.2e-55 188.3 0.0 1.8 2 0 0 2 2 2 1 RNase P subunit p30 zinc_ribbon_15 PF17032.5 KPA45580.1 - 9.7e-05 23.0 0.3 0.00014 22.5 0.3 1.2 1 0 0 1 1 1 1 zinc-ribbon family RNA_POL_M_15KD PF02150.16 KPA45580.1 - 0.067 13.1 1.4 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit SWIRM-assoc_2 PF16496.5 KPA45581.1 - 6.2e-06 25.3 2.0 6.2e-06 25.3 2.0 3.7 4 1 0 4 4 4 1 SWIRM-associated domain at the N-terminal BRCT PF00533.26 KPA45581.1 - 0.0049 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AT_hook PF02178.19 KPA45581.1 - 0.12 12.3 18.9 2.1 8.5 0.3 4.6 3 0 0 3 3 3 0 AT hook motif PTCB-BRCT PF12738.7 KPA45581.1 - 0.15 12.0 0.0 16 5.5 0.0 2.4 2 0 0 2 2 2 0 twin BRCT domain MgtE_N PF03448.17 KPA45582.1 - 0.048 14.3 1.4 0.46 11.1 0.2 2.1 2 0 0 2 2 2 0 MgtE intracellular N domain DAHP_synth_2 PF01474.16 KPA45583.1 - 3.4e-200 665.1 0.0 3.9e-200 665.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Aldose_epim PF01263.20 KPA45584.1 - 1.6e-42 145.9 0.0 1.9e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Sugar_tr PF00083.24 KPA45585.1 - 2.9e-114 382.4 21.5 3.7e-114 382.1 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA45585.1 - 4.8e-21 75.1 33.5 1.5e-15 57.0 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KPA45585.1 - 0.0022 16.4 4.4 0.0022 16.4 4.4 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family SurA_N_3 PF13624.6 KPA45585.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 SurA N-terminal domain HisK_sensor PF18698.1 KPA45586.1 - 0.2 12.1 0.2 0.42 11.0 0.2 1.5 1 0 0 1 1 1 0 Histidine kinase sensor domain gag-asp_proteas PF13975.6 KPA45587.1 - 0.0084 16.7 0.0 0.021 15.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Pox_P4B PF03292.14 KPA45587.1 - 0.016 13.5 0.2 0.024 12.9 0.2 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein Asp_protease_2 PF13650.6 KPA45587.1 - 0.02 15.5 0.0 0.054 14.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Pneumo_att_G PF05539.11 KPA45587.1 - 4.4 6.8 6.9 42 3.6 6.9 2.1 1 1 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Arrestin_C PF02752.22 KPA45588.1 - 2.6e-14 53.8 2.0 4.1e-14 53.2 0.2 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.7 KPA45589.1 - 1.6e-22 79.5 1.2 3.8e-22 78.2 1.2 1.7 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KPA45589.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain PQ-loop PF04193.14 KPA45590.1 - 3.4e-26 90.8 2.3 6.3e-18 64.3 0.4 2.9 2 1 0 2 2 2 2 PQ loop repeat SLATT_1 PF18181.1 KPA45590.1 - 0.14 12.0 3.1 0.22 11.5 0.5 2.2 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Peptidase_U4 PF03419.13 KPA45590.1 - 0.34 10.1 9.0 0.17 11.1 5.7 1.9 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Zip PF02535.22 KPA45591.1 - 0.87 8.7 2.0 1.3 8.1 2.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KPA45591.1 - 1.7 7.3 6.7 2.3 6.9 6.7 1.2 1 0 0 1 1 1 0 Presenilin Amidase PF01425.21 KPA45592.1 - 3e-86 290.1 0.0 4.1e-86 289.7 0.0 1.2 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 KPA45592.1 - 9.8e-85 284.4 0.0 2.6e-84 282.9 0.0 1.8 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KPA45592.1 - 1.9e-59 200.7 0.0 3.6e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KPA45592.1 - 4.4e-35 120.6 0.1 2e-34 118.4 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 KPA45592.1 - 3.7e-34 118.2 0.0 7.5e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 KPA45592.1 - 3.3e-30 104.3 0.0 1.1e-29 102.7 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KPA45592.1 - 7.8e-13 48.1 2.0 1.7e-12 47.0 2.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KPA45592.1 - 8.1e-07 28.8 0.0 2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KPA45592.1 - 0.00033 20.4 0.1 0.1 12.4 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.11 KPA45592.1 - 0.0033 17.0 0.0 0.0083 15.7 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GCV_H PF01597.19 KPA45592.1 - 0.0068 16.3 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KPA45592.1 - 0.14 12.1 0.3 0.31 11.0 0.3 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain UDPGT PF00201.18 KPA45593.1 - 7.8e-10 38.1 0.0 1.5e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_4 PF13439.6 KPA45593.1 - 0.017 15.1 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KPA45593.1 - 0.069 13.6 0.4 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_tran_28_C PF04101.16 KPA45593.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain ABC_membrane PF00664.23 KPA45594.1 - 9.7e-41 140.2 12.6 1.2e-40 139.9 12.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KPA45594.1 - 7.4e-33 114.0 0.0 1.7e-32 112.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KPA45594.1 - 1.8e-05 24.3 0.0 0.0043 16.5 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KPA45594.1 - 0.00013 22.4 0.1 0.00029 21.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA45594.1 - 0.00074 19.8 0.0 0.0033 17.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KPA45594.1 - 0.0023 17.8 0.1 0.06 13.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KPA45594.1 - 0.0038 17.1 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 KPA45594.1 - 0.0094 16.0 0.0 0.052 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KPA45594.1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPA45594.1 - 0.02 15.4 0.0 0.17 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KPA45594.1 - 0.02 15.0 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 KPA45594.1 - 0.022 15.2 0.0 0.13 12.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KPA45594.1 - 0.023 14.9 0.0 0.083 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KPA45594.1 - 0.04 13.7 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KPA45594.1 - 0.05 12.9 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.15 KPA45594.1 - 0.064 13.2 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 KPA45594.1 - 0.084 12.6 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KPA45594.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KPA45594.1 - 0.095 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_7 PF12775.7 KPA45594.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KPA45594.1 - 0.16 12.2 0.4 3.3 8.0 0.4 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit p450 PF00067.22 KPA45595.1 - 1.3e-12 47.2 0.0 3.9e-11 42.4 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 RseA_N PF03872.13 KPA45595.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain ACOX PF01756.19 KPA45595.1 - 0.14 11.8 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 Acyl-CoA oxidase Band_7 PF01145.25 KPA45596.1 - 3.5e-29 102.1 2.6 5.5e-29 101.4 2.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KPA45596.1 - 0.0054 16.5 1.3 0.0067 16.2 0.3 1.6 2 0 0 2 2 2 1 SPFH domain-Band 7 family Nop PF01798.18 KPA45597.1 - 3.8e-79 265.4 0.2 7.4e-79 264.4 0.2 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KPA45597.1 - 1.9e-20 73.0 1.8 1.9e-20 73.0 1.8 3.0 3 0 0 3 3 3 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.16 KPA45598.1 - 9.1e-109 364.0 0.0 1e-108 363.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.22 KPA45599.1 - 4.5e-25 87.7 0.6 5.4e-24 84.2 0.5 2.5 2 0 0 2 2 2 1 Ribosomal protein S15 CcdA PF07362.12 KPA45599.1 - 0.018 15.4 0.1 0.018 15.4 0.1 2.3 2 1 0 2 2 2 0 Post-segregation antitoxin CcdA SAE2 PF08573.10 KPA45599.1 - 0.049 14.7 0.4 0.049 14.7 0.4 2.8 3 0 0 3 3 3 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Glyco_hydro_99 PF16317.5 KPA45599.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 99 Ribosomal_S2 PF00318.20 KPA45600.1 - 7.5e-25 87.4 0.5 2.1e-13 50.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KPA45600.1 - 2.7e-06 28.6 14.4 5.1e-06 27.8 14.4 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Collagen PF01391.18 KPA45600.1 - 1.4 8.7 4.8 2.4 8.0 4.8 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) RasGEF PF00617.19 KPA45601.1 - 7.7e-48 163.0 0.1 1.3e-47 162.2 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KPA45601.1 - 2.6e-13 50.1 0.1 5.9e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif AAA PF00004.29 KPA45602.1 - 9.2e-52 175.0 0.0 1e-38 132.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA45602.1 - 3.5e-11 43.5 0.0 0.00024 21.4 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KPA45602.1 - 2.3e-10 40.1 0.2 7.3e-10 38.5 0.2 1.9 1 1 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KPA45602.1 - 7.7e-10 39.4 0.0 0.0026 18.2 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 KPA45602.1 - 1.7e-09 37.8 0.0 0.0011 19.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KPA45602.1 - 8.3e-09 35.1 0.0 0.0017 17.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 KPA45602.1 - 9.6e-08 31.7 0.1 6.1e-06 25.9 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 ATPase_2 PF01637.18 KPA45602.1 - 1.5e-07 31.6 0.1 0.24 11.3 0.0 4.1 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KPA45602.1 - 4.5e-07 30.5 0.0 0.054 14.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KPA45602.1 - 9e-07 29.2 0.0 0.048 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KPA45602.1 - 1.5e-06 28.4 0.0 0.00022 21.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KPA45602.1 - 1.7e-06 28.4 0.0 0.064 13.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 KPA45602.1 - 1.9e-06 27.7 0.2 0.052 13.3 0.1 3.1 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KPA45602.1 - 3.6e-06 27.0 0.0 0.059 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KPA45602.1 - 1.3e-05 24.7 1.0 0.0041 16.5 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KPA45602.1 - 1.3e-05 25.1 0.0 0.15 11.8 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KPA45602.1 - 2e-05 24.2 0.2 0.047 13.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 KPA45602.1 - 5.4e-05 23.2 0.0 0.45 10.5 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KPA45602.1 - 7.2e-05 22.8 0.8 0.06 13.3 0.1 3.3 3 0 0 3 3 3 1 NACHT domain AAA_24 PF13479.6 KPA45602.1 - 0.00016 21.5 0.0 0.028 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KPA45602.1 - 0.00033 20.4 0.1 0.81 9.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 KPA45602.1 - 0.00065 19.0 0.6 0.49 9.5 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain AAA_28 PF13521.6 KPA45602.1 - 0.0007 19.9 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KPA45602.1 - 0.00078 20.0 0.5 0.39 11.2 0.1 2.6 2 0 0 2 2 2 1 ABC transporter ATPase PF06745.13 KPA45602.1 - 0.0026 17.1 1.3 0.035 13.5 0.2 2.2 2 0 0 2 2 2 1 KaiC ResIII PF04851.15 KPA45602.1 - 0.0027 17.7 0.1 3 7.8 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KPA45602.1 - 0.0029 17.1 0.1 2 7.8 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.17 KPA45602.1 - 0.0052 15.9 0.0 0.98 8.4 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KPA45602.1 - 0.0058 16.2 0.6 3.9 7.0 0.1 2.6 3 0 0 3 3 2 1 AAA domain DAP3 PF10236.9 KPA45602.1 - 0.006 15.8 0.0 0.44 9.7 0.0 2.8 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.6 KPA45602.1 - 0.0065 16.9 0.1 3.1 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KPA45602.1 - 0.0091 15.8 0.0 0.72 9.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPA45602.1 - 0.012 15.3 0.1 0.51 10.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_3 PF07726.11 KPA45602.1 - 0.034 14.0 0.0 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 KPA45602.1 - 0.045 13.6 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_19 PF13245.6 KPA45602.1 - 0.048 14.0 0.1 0.98 9.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain TniB PF05621.11 KPA45602.1 - 0.067 12.6 0.1 4.6 6.6 0.1 3.0 2 1 0 2 2 2 0 Bacterial TniB protein DUF2075 PF09848.9 KPA45602.1 - 0.067 12.4 0.2 1.7 7.8 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 KPA45602.1 - 0.092 12.5 1.4 4 7.3 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain DNA_pol3_delta2 PF13177.6 KPA45602.1 - 0.1 12.4 0.0 4 7.2 0.0 2.8 2 1 0 2 2 2 0 DNA polymerase III, delta subunit AAA_23 PF13476.6 KPA45602.1 - 0.12 12.8 0.0 2.9 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KPA45602.1 - 0.14 12.2 0.0 32 4.6 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain IPT PF01745.16 KPA45602.1 - 0.22 10.9 0.1 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Cir_N PF10197.9 KPA45603.1 - 3.3e-08 33.6 0.6 3.3e-08 33.6 0.6 4.2 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.8 KPA45603.1 - 3.6 8.6 13.8 0.46 11.4 4.4 3.3 2 1 1 3 3 3 0 Pre-mRNA splicing factor YadA_head PF05658.14 KPA45605.1 - 0.0024 18.2 4.1 0.0054 17.1 4.1 1.6 1 0 0 1 1 1 1 Head domain of trimeric autotransporter adhesin KxDL PF10241.9 KPA45606.1 - 5.3e-32 110.0 2.2 7.4e-32 109.5 2.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein XylR_N PF06505.11 KPA45606.1 - 0.058 13.1 0.3 0.091 12.5 0.3 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism UPF0242 PF06785.11 KPA45606.1 - 0.32 11.1 3.0 0.44 10.6 3.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF883 PF05957.13 KPA45606.1 - 2.6 8.7 6.4 12 6.6 2.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DEAD PF00270.29 KPA45609.1 - 6.1e-37 127.1 0.0 1.4e-36 125.9 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA45609.1 - 4e-21 75.4 0.0 1.2e-20 73.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KPA45609.1 - 6.3e-19 68.0 0.0 1.1e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KPA45609.1 - 0.0011 19.1 0.1 0.007 16.4 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KPA45609.1 - 0.046 14.0 0.0 0.22 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.11 KPA45609.1 - 2.8 6.3 17.5 3.7 5.9 17.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Zn_clus PF00172.18 KPA45610.1 - 1.6e-07 31.3 9.1 3.3e-07 30.3 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRM1_C PF08767.11 KPA45611.1 - 8.8e-131 435.8 6.0 8.8e-131 435.8 6.0 2.9 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KPA45611.1 - 1.4e-41 142.0 7.9 1.4e-41 142.0 7.9 3.9 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KPA45611.1 - 1.1e-33 114.6 4.2 3.8e-33 112.9 4.2 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KPA45611.1 - 9.9e-28 96.0 1.2 9.9e-28 96.0 1.2 3.2 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KPA45611.1 - 5.6e-18 64.2 1.3 1.7e-17 62.6 1.3 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KPA45611.1 - 1.7e-14 53.4 0.1 6.9e-14 51.5 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KPA45611.1 - 0.01 15.8 7.8 0.36 10.7 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) HD_assoc PF13286.6 KPA45611.1 - 0.027 15.0 1.1 49 4.6 0.0 4.5 5 0 0 5 5 5 0 Phosphohydrolase-associated domain Hemocyanin_M PF00372.19 KPA45611.1 - 0.055 12.6 0.8 0.3 10.3 0.1 2.4 2 1 1 3 3 3 0 Hemocyanin, copper containing domain Vac14_Fab1_bd PF12755.7 KPA45611.1 - 0.44 11.2 2.6 6.7 7.4 0.0 4.2 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Aminotran_5 PF00266.19 KPA45612.1 - 4.6e-24 85.1 0.0 6e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KPA45612.1 - 0.0042 17.1 0.2 0.053 13.6 0.0 2.6 2 2 0 2 2 2 1 B12 binding domain Abhydrolase_6 PF12697.7 KPA45613.1 - 5e-19 69.8 2.1 6.9e-19 69.3 2.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA45613.1 - 4.1e-14 52.4 0.9 3.3e-13 49.5 0.9 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA45613.1 - 1.2e-13 51.4 0.4 2.2e-11 43.9 0.7 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KPA45613.1 - 0.051 13.4 0.8 0.25 11.1 0.8 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KPA45613.1 - 0.13 12.4 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 Thioesterase domain EDS1_EP PF18117.1 KPA45613.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Enhanced disease susceptibility 1 protein EP domain PGAP1 PF07819.13 KPA45613.1 - 0.34 10.6 1.1 0.71 9.6 1.1 1.6 1 1 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.18 KPA45614.1 - 3.7e-07 29.4 0.1 7.9e-07 28.4 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain CNOT1_HEAT_N PF16419.5 KPA45614.1 - 0.022 14.4 0.9 0.035 13.8 0.2 1.7 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat AA_permease PF00324.21 KPA45615.1 - 2e-137 458.7 34.8 2.4e-137 458.4 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA45615.1 - 8e-36 123.8 36.4 1.1e-35 123.4 36.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1741 PF08427.10 KPA45616.1 - 5.4e-88 294.6 0.3 1.1e-87 293.6 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) RasGEF PF00617.19 KPA45617.1 - 7.8e-53 179.3 0.0 1.5e-52 178.4 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KPA45617.1 - 7.3e-16 58.3 0.0 6.7e-15 55.2 0.0 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 KPA45617.1 - 3.3e-06 26.8 0.0 6.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPA45617.1 - 0.0005 19.6 0.0 0.00096 18.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain CHASE3 PF05227.13 KPA45617.1 - 0.091 12.7 0.2 0.22 11.4 0.2 1.7 1 0 0 1 1 1 0 CHASE3 domain Sugar_tr PF00083.24 KPA45618.1 - 3.7e-67 227.1 17.1 4.8e-67 226.8 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA45618.1 - 1.5e-15 57.0 26.6 3.5e-15 55.8 26.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0139 PF03669.13 KPA45618.1 - 1.8 8.5 6.1 1.4 8.8 0.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) FAD_binding_3 PF01494.19 KPA45619.1 - 6.7e-12 45.3 1.8 3.3e-08 33.2 0.4 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KPA45619.1 - 3.2e-08 33.1 0.3 0.00049 19.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA45619.1 - 6.2e-06 26.3 0.0 2e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPA45619.1 - 9.2e-06 25.0 0.1 1.5e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPA45619.1 - 0.00036 19.4 0.2 0.0032 16.2 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KPA45619.1 - 0.00046 19.4 0.1 0.0012 18.0 0.1 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KPA45619.1 - 0.0019 17.7 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA45619.1 - 0.0049 17.4 0.2 0.11 13.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA45619.1 - 0.007 16.0 0.1 0.036 13.7 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KPA45619.1 - 0.018 13.9 0.0 3.1 6.6 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KPA45619.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain La PF05383.17 KPA45620.1 - 6.9e-18 64.4 0.4 1.5e-17 63.4 0.4 1.6 1 0 0 1 1 1 1 La domain Got1 PF04178.12 KPA45621.1 - 6.1e-34 116.8 17.5 7.9e-34 116.5 17.5 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family HLH PF00010.26 KPA45623.1 - 4.1e-12 45.9 0.1 1.9e-11 43.7 0.1 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain NPR3 PF03666.13 KPA45624.1 - 2.5e-144 481.5 0.1 2.5e-144 481.5 0.1 1.9 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 KPA45624.1 - 0.013 14.3 0.1 0.027 13.2 0.1 1.5 1 0 0 1 1 1 0 Nitrogen permease regulator 2 Choline_kinase PF01633.20 KPA45625.1 - 1.8e-48 165.0 0.0 8.3e-48 162.8 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KPA45625.1 - 6.1e-07 29.6 4.9 1.4e-06 28.4 5.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KPA45625.1 - 0.0035 16.3 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KPA45625.1 - 0.0041 16.5 0.1 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase Exo_endo_phos_2 PF14529.6 KPA45626.1 - 0.0013 18.5 0.1 0.032 14.1 0.0 2.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Zn_clus PF00172.18 KPA45626.1 - 0.68 10.1 14.3 0.025 14.7 7.6 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-Di19 PF05605.12 KPA45626.1 - 1.8 8.9 16.8 18 5.7 0.7 4.7 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Sugar_tr PF00083.24 KPA45627.1 - 1.9e-24 86.4 23.3 3.2e-15 55.9 7.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3611 PF12263.8 KPA45627.1 - 0.0075 16.2 0.5 0.0075 16.2 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3611) Pkinase PF00069.25 KPA45628.1 - 3.9e-61 206.7 0.0 1.7e-38 132.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA45628.1 - 9.3e-28 97.2 0.0 3.1e-20 72.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KPA45628.1 - 1.1e-15 57.7 0.0 2.7e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KPA45628.1 - 4.5e-07 29.5 0.1 0.00033 20.1 0.0 2.8 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KPA45628.1 - 0.0001 22.3 0.0 0.0034 17.4 0.1 2.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KPA45628.1 - 0.0059 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KPA45628.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 KPA45628.1 - 0.0069 16.6 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 PAS domain Seadorna_VP7 PF07387.11 KPA45628.1 - 0.032 13.3 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 bZIP_1 PF00170.21 KPA45629.1 - 6e-05 23.1 8.4 0.00012 22.2 8.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPA45629.1 - 0.018 15.1 7.1 0.027 14.5 3.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper PAP1 PF08601.10 KPA45629.1 - 0.16 11.7 4.5 2 8.0 0.0 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 eIF-3_zeta PF05091.12 KPA45630.1 - 1.8e-204 680.6 0.0 2.2e-204 680.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SH3_9 PF14604.6 KPA45631.1 - 6.3e-32 109.2 4.3 5.7e-17 61.3 0.5 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KPA45631.1 - 4.2e-29 99.9 4.2 4.6e-15 55.0 0.3 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KPA45631.1 - 7.4e-17 60.8 0.0 1.8e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 KPA45631.1 - 1.2e-15 57.4 0.0 2.3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2613 PF11021.8 KPA45631.1 - 0.036 14.2 2.7 0.12 12.5 2.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Glutaredoxin PF00462.24 KPA45632.1 - 8.6e-18 64.3 0.0 9.8e-17 60.9 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KPA45632.1 - 1.4e-14 54.0 0.0 2.9e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KPA45632.1 - 0.00075 19.8 0.0 0.65 10.4 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KPA45632.1 - 0.009 16.5 0.1 0.24 11.9 0.0 2.9 2 2 1 3 3 3 1 Thioredoxin-like domain HyaE PF07449.11 KPA45632.1 - 0.019 14.9 0.0 0.12 12.4 0.0 2.2 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Disulph_isomer PF06491.11 KPA45632.1 - 0.061 13.4 0.0 1 9.4 0.0 2.5 2 1 0 2 2 2 0 Disulphide isomerase Ribosomal_60s PF00428.19 KPA45632.1 - 0.11 13.1 1.9 0.28 11.8 1.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Fungal_trans PF04082.18 KPA45633.1 - 1.3e-14 53.9 0.1 2e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA45633.1 - 0.0087 16.2 9.1 0.029 14.5 9.1 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.19 KPA45633.1 - 0.59 10.8 3.5 1.5 9.4 3.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein F-box-like PF12937.7 KPA45634.1 - 0.018 14.9 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KPA45634.1 - 0.02 14.8 0.1 0.069 13.1 0.0 1.9 2 0 0 2 2 2 0 F-box domain Dynamin_M PF01031.20 KPA45635.1 - 2.2e-109 365.1 0.0 3.9e-109 364.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KPA45635.1 - 3e-56 190.1 0.0 5.8e-56 189.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KPA45635.1 - 1.6e-30 105.1 1.4 1.6e-30 105.1 1.4 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KPA45635.1 - 5.6e-05 23.2 0.2 0.00042 20.4 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase CHCH PF06747.13 KPA45636.1 - 5.3e-06 26.4 2.3 7.5e-06 25.9 2.3 1.2 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 KPA45636.1 - 0.0018 18.6 3.9 0.11 12.9 0.4 2.3 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 KPA45636.1 - 0.0075 16.5 3.9 0.038 14.3 3.9 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 LIM PF00412.22 KPA45637.1 - 2.1e-22 79.1 30.2 5.8e-08 32.9 1.2 3.4 3 0 0 3 3 3 3 LIM domain zf-dskA_traR PF01258.17 KPA45637.1 - 0.94 9.5 20.4 0.42 10.6 0.5 5.4 4 1 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger DUF2321 PF10083.9 KPA45637.1 - 1.3 8.7 12.9 0.04 13.5 0.6 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn_ribbon_recom PF13408.6 KPA45637.1 - 3.2 8.4 21.1 0.27 11.8 5.4 3.6 4 0 0 4 4 4 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.10 KPA45637.1 - 9 6.5 23.7 1 9.5 1.1 4.9 4 1 1 5 5 5 0 Zinc ribbon domain Rad60-SLD PF11976.8 KPA45638.1 - 1.7e-20 72.6 0.1 2.1e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KPA45638.1 - 1.6e-10 40.6 0.1 1.8e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family HH_signal PF01085.18 KPA45638.1 - 0.13 11.9 0.1 0.14 11.8 0.1 1.0 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Nup84_Nup100 PF04121.13 KPA45639.1 - 3.1e-201 670.3 0.2 3.6e-201 670.1 0.2 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Mod_r PF07200.13 KPA45640.1 - 3e-35 121.5 5.3 3.5e-35 121.2 5.3 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein F-box PF00646.33 KPA45642.1 - 1e-05 25.2 0.1 2.6e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KPA45642.1 - 3.7e-05 23.5 0.1 3.7e-05 23.5 0.1 2.3 3 0 0 3 3 3 1 F-box-like SUIM_assoc PF16619.5 KPA45642.1 - 1.3 9.2 10.1 0.068 13.2 3.8 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Parvo_coat PF00740.18 KPA45643.1 - 0.0045 15.7 2.1 0.007 15.1 2.1 1.2 1 0 0 1 1 1 1 Parvovirus coat protein VP2 Lipoprotein_16 PF03923.13 KPA45643.1 - 0.073 12.7 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized lipoprotein AT_hook PF02178.19 KPA45643.1 - 0.25 11.3 17.3 1.3 9.1 2.5 2.9 2 0 0 2 2 2 0 AT hook motif V-ATPase_C PF03223.15 KPA45645.1 - 1.4e-116 390.0 0.0 1.6e-116 389.8 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C PBP_dimer PF03717.15 KPA45645.1 - 0.0053 17.1 0.1 0.017 15.5 0.1 1.8 2 0 0 2 2 2 1 Penicillin-binding Protein dimerisation domain mRNA_cap_C PF03919.15 KPA45645.1 - 0.0092 16.6 0.1 0.023 15.3 0.1 1.8 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain APS_kinase PF01583.20 KPA45646.1 - 4.6e-73 244.3 0.0 5.6e-73 244.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KPA45646.1 - 5.8e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KPA45646.1 - 1e-05 26.1 0.0 2.7e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KPA45646.1 - 0.00076 19.0 0.0 0.00093 18.7 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KPA45646.1 - 0.004 16.4 0.0 0.028 13.7 0.0 2.1 1 1 1 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KPA45646.1 - 0.0073 16.7 0.1 0.011 16.1 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain PRK PF00485.18 KPA45646.1 - 0.035 13.8 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family 6PF2K PF01591.18 KPA45646.1 - 0.048 13.0 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CPT PF07931.12 KPA45646.1 - 0.049 13.5 0.2 0.17 11.7 0.2 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF463 PF04317.12 KPA45646.1 - 0.073 12.0 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_29 PF13555.6 KPA45646.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain 4HBT PF03061.22 KPA45647.1 - 1.3e-10 41.5 0.0 2.6e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily CBF PF03914.17 KPA45649.1 - 3.7e-49 167.0 0.0 3.7e-49 167.0 0.0 2.8 2 1 0 2 2 2 1 CBF/Mak21 family Cnd1 PF12717.7 KPA45649.1 - 0.016 15.2 0.1 0.042 13.9 0.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 tRNA-synt_2b PF00587.25 KPA45650.1 - 1.2e-27 97.0 0.0 3e-27 95.8 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KPA45650.1 - 1.7e-10 40.9 0.0 3.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Prefoldin PF02996.17 KPA45651.1 - 4.2e-22 78.3 0.3 4.2e-22 78.3 0.3 1.5 2 0 0 2 2 2 1 Prefoldin subunit UvsW PF11637.8 KPA45651.1 - 0.002 18.2 0.2 0.0049 16.9 0.2 1.6 1 0 0 1 1 1 1 ATP-dependant DNA helicase UvsW CLZ PF16526.5 KPA45651.1 - 0.0033 17.8 6.7 0.39 11.1 0.7 2.3 2 0 0 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TACC_C PF05010.14 KPA45651.1 - 0.021 14.6 10.1 0.11 12.3 1.6 2.1 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cep57_MT_bd PF06657.13 KPA45651.1 - 0.098 13.1 0.3 0.098 13.1 0.3 2.5 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Med10 PF09748.9 KPA45651.1 - 0.2 11.6 3.9 0.7 9.9 0.3 2.1 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DUF1664 PF07889.12 KPA45651.1 - 0.53 10.3 3.4 2.3 8.3 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FXMRP1_C_core PF12235.8 KPA45652.1 - 0.11 13.1 2.4 0.2 12.3 2.4 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal AAA PF00004.29 KPA45653.1 - 4.2e-16 59.6 0.0 7.9e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KPA45653.1 - 2.8e-11 43.4 0.1 7.6e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 KPA45653.1 - 4.7e-11 43.4 0.3 7.5e-10 39.5 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPA45653.1 - 7.1e-09 36.1 0.0 1.5e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 KPA45653.1 - 3.4e-07 30.2 0.0 8.3e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 KPA45653.1 - 0.0018 18.7 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KPA45653.1 - 0.0041 17.7 0.0 0.0095 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KPA45653.1 - 0.0046 16.9 0.0 0.069 13.1 0.0 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KPA45653.1 - 0.014 15.4 0.0 0.032 14.2 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 KPA45653.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KPA45653.1 - 0.028 13.7 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 KPA45653.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 KPA45653.1 - 0.1 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain RNA_helicase PF00910.22 KPA45653.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KPA45653.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 KPA45653.1 - 0.17 10.6 0.0 0.33 9.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KPA45653.1 - 0.25 10.5 0.0 0.58 9.3 0.0 1.5 2 0 0 2 2 2 0 PIF1-like helicase WD40 PF00400.32 KPA45654.1 - 9e-45 149.8 17.2 6.3e-09 36.3 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA45654.1 - 0.00011 22.4 0.7 16 5.9 0.0 4.7 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Zeta_toxin PF06414.12 KPA45654.1 - 0.0087 15.3 0.7 0.016 14.5 0.7 1.4 1 0 0 1 1 1 1 Zeta toxin Nup160 PF11715.8 KPA45654.1 - 0.018 13.7 3.6 10 4.6 0.0 4.4 1 1 4 5 5 5 0 Nucleoporin Nup120/160 Ank_5 PF13857.6 KPA45655.1 - 7e-39 131.4 3.7 4.9e-10 39.4 0.1 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPA45655.1 - 3.3e-33 113.6 1.0 1.2e-07 32.1 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA45655.1 - 1.1e-32 112.4 0.0 8.7e-11 42.3 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA45655.1 - 1.4e-27 92.7 0.0 0.0025 18.2 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KPA45655.1 - 1.6e-23 82.1 0.0 0.018 15.5 0.1 6.2 6 0 0 6 6 6 5 Ankyrin repeat TMF_TATA_bd PF12325.8 KPA45656.1 - 3.9e-39 133.4 9.3 3.9e-39 133.4 9.3 6.6 4 2 3 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KPA45656.1 - 1.7e-14 53.6 15.3 1.7e-14 53.6 15.3 8.7 4 3 3 8 8 8 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KPA45656.1 - 0.00018 21.8 1.3 0.00018 21.8 1.3 6.8 3 1 3 6 6 6 2 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 KPA45656.1 - 0.45 11.0 12.2 4.6 7.8 0.4 5.3 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KPA45656.1 - 2.6 8.5 0.0 0.74 10.3 5.3 6.9 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) DUF2459 PF09601.10 KPA45657.1 - 8.7 6.1 6.8 4.6 7.0 2.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2459) zf-C2H2 PF00096.26 KPA45659.1 - 2.1e-10 40.5 22.4 3.6e-06 27.1 2.4 4.0 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPA45659.1 - 1.6e-08 34.6 22.6 1.9e-07 31.2 0.2 4.2 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPA45659.1 - 1.1e-07 32.0 15.9 0.0004 21.0 1.5 4.3 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KPA45659.1 - 1.6e-07 31.1 8.4 0.00032 20.6 0.3 3.9 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA45659.1 - 1.2e-06 28.6 0.3 0.088 13.1 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPA45659.1 - 4.7e-05 23.6 1.7 0.013 15.8 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KPA45659.1 - 0.052 13.8 1.4 0.13 12.5 1.4 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 KPA45659.1 - 0.15 12.6 1.9 4.9 7.7 0.2 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_recom PF13408.6 KPA45659.1 - 0.2 12.2 0.7 0.44 11.1 0.7 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_11 PF16622.5 KPA45659.1 - 0.47 10.3 14.1 0.41 10.5 0.7 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type LIM PF00412.22 KPA45659.1 - 0.52 10.6 3.7 17 5.7 0.1 2.4 1 1 1 2 2 2 0 LIM domain FYVE PF01363.21 KPA45659.1 - 2.8 8.1 5.2 5.2 7.3 5.2 1.4 1 0 0 1 1 1 0 FYVE zinc finger C5HCH PF17982.1 KPA45659.1 - 4.4 7.5 6.8 26 5.1 0.4 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain AOX PF01786.17 KPA45660.1 - 4.2e-94 314.1 0.0 5.4e-94 313.8 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase eIF3_subunit PF08597.10 KPA45661.1 - 2e-70 237.5 29.1 2.2e-70 237.3 29.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit YL1 PF05764.13 KPA45661.1 - 0.002 18.3 14.9 0.002 18.3 14.9 2.0 2 0 0 2 2 2 1 YL1 nuclear protein IHABP4_N PF16174.5 KPA45661.1 - 8.3 7.0 22.1 0.39 11.3 12.2 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal MDM31_MDM32 PF08118.11 KPA45662.1 - 1.7e-248 825.6 0.0 2e-248 825.3 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_8 PF17903.1 KPA45663.1 - 7e-05 22.8 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KPA45663.1 - 0.0082 15.9 0.3 0.02 14.7 0.3 1.7 1 0 0 1 1 1 1 KH domain Enolase_C PF00113.22 KPA45664.1 - 1.1e-151 504.1 0.0 1.6e-151 503.6 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KPA45664.1 - 8.6e-58 194.2 0.4 1.7e-57 193.2 0.4 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KPA45664.1 - 1.4e-05 24.8 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KPA45664.1 - 0.016 14.3 0.6 0.55 9.3 0.1 2.6 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus Mad3_BUB1_I PF08311.12 KPA45665.1 - 5e-43 146.0 0.2 1e-42 145.0 0.2 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 KPA45665.1 - 1.5e-08 34.6 0.0 4.2e-07 30.0 0.0 3.2 4 0 0 4 4 4 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KPA45665.1 - 5.5e-08 32.5 0.0 3e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA45665.1 - 0.00016 21.0 0.0 0.00095 18.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3811 PF11656.8 KPA45666.1 - 0.073 13.5 2.7 0.094 13.1 2.7 1.3 1 0 0 1 1 1 0 YjbD family (DUF3811) zf-H2C2_2 PF13465.6 KPA45667.1 - 3.1e-13 49.5 18.2 5e-07 29.9 2.3 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KPA45667.1 - 7.2e-11 41.9 23.6 0.0021 18.4 8.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA45667.1 - 5.1e-07 30.0 19.5 0.02 15.7 6.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger Rad50_zn_hook PF04423.14 KPA45667.1 - 0.00068 19.4 2.7 0.12 12.3 0.4 2.6 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 KPA45667.1 - 0.0016 18.4 17.3 0.14 12.2 0.1 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KPA45667.1 - 0.013 15.3 3.1 2.3 8.1 0.2 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 KPA45667.1 - 0.027 14.6 6.2 0.12 12.5 2.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-CHCC PF10276.9 KPA45667.1 - 0.037 14.1 2.4 2.1 8.4 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger domain Zn_ribbon_SprT PF17283.2 KPA45667.1 - 0.19 11.6 6.5 0.56 10.2 1.0 2.6 2 1 0 2 2 2 0 SprT-like zinc ribbon domain ZapB PF06005.12 KPA45667.1 - 0.19 12.2 0.2 0.19 12.2 0.2 2.2 3 0 0 3 3 1 0 Cell division protein ZapB DZR PF12773.7 KPA45667.1 - 0.29 11.2 7.1 2.2 8.4 7.1 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF16 PF01519.16 KPA45667.1 - 0.42 11.1 2.6 1 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 zf-C2HC_2 PF13913.6 KPA45667.1 - 0.43 10.5 6.2 0.23 11.4 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF3268 PF11672.8 KPA45667.1 - 0.76 10.1 2.9 3.2 8.1 2.9 1.9 1 1 0 1 1 1 0 zinc-finger-containing domain zf-Di19 PF05605.12 KPA45667.1 - 0.9 9.9 18.6 0.05 13.9 6.6 3.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 KPA45667.1 - 1.1 9.6 6.7 11 6.4 0.1 3.2 2 1 1 3 3 3 0 zinc-ribbon TF_Zn_Ribbon PF08271.12 KPA45667.1 - 1.1 8.8 4.6 2.7 7.6 1.4 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding HypA PF01155.19 KPA45667.1 - 1.3 9.1 3.4 5.6 7.0 3.3 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-BED PF02892.15 KPA45667.1 - 1.4 9.0 10.4 0.6 10.2 4.7 2.8 2 1 1 3 3 3 0 BED zinc finger Zn_Tnp_IS1595 PF12760.7 KPA45667.1 - 3.8 7.6 8.5 12 6.0 3.4 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GAGA PF09237.11 KPA45667.1 - 4.3 7.2 6.4 3.5 7.5 0.5 2.9 1 1 2 3 3 3 0 GAGA factor zinc-ribbons_6 PF07191.12 KPA45667.1 - 6.5 6.8 6.2 38 4.4 6.2 2.1 1 1 0 1 1 1 0 zinc-ribbons zf-UDP PF14569.6 KPA45667.1 - 9.3 6.4 9.3 7.9 6.7 0.5 2.9 1 1 1 2 2 2 0 Zinc-binding RING-finger SUN PF03856.13 KPA45668.1 - 6.7e-94 313.9 10.2 9.2e-94 313.5 10.2 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Vma12 PF11712.8 KPA45669.1 - 0.16 12.1 0.3 0.23 11.5 0.3 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase LapA_dom PF06305.11 KPA45669.1 - 2.7 7.8 11.7 1.4 8.8 0.1 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Hist_deacetyl PF00850.19 KPA45671.1 - 1.7e-78 264.2 0.0 2.3e-78 263.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.7 KPA45672.1 - 7.4e-24 84.3 4.9 1.1e-23 83.7 4.9 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KPA45672.1 - 0.00019 21.2 9.3 0.00019 21.2 9.3 1.6 2 0 0 2 2 2 1 PHD-finger DUF2552 PF10827.8 KPA45672.1 - 0.054 13.7 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2552) zf-HC5HC2H PF13771.6 KPA45672.1 - 0.11 12.8 1.0 0.22 11.8 1.0 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 KPA45672.1 - 1.1 9.7 6.4 2.1 8.8 6.4 1.5 1 0 0 1 1 1 0 Ring finger domain Methyltransf_16 PF10294.9 KPA45673.1 - 0.016 14.9 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Lysine methyltransferase Complex1_LYR_2 PF13233.6 KPA45674.1 - 1.4e-20 73.8 0.1 2e-20 73.3 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KPA45674.1 - 7.7e-11 41.9 0.2 1.8e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) RPAP1_N PF08621.10 KPA45674.1 - 0.074 12.8 1.3 0.18 11.6 1.3 1.8 1 1 0 1 1 1 0 RPAP1-like, N-terminal HA2 PF04408.23 KPA45675.1 - 5.2e-18 65.3 0.8 2.3e-17 63.2 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KPA45675.1 - 2.8e-13 50.2 0.0 9.6e-13 48.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KPA45675.1 - 6.1e-11 42.5 0.1 2.4e-10 40.6 0.1 2.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KPA45675.1 - 6.1e-06 26.6 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KPA45675.1 - 1.4e-05 25.0 0.0 2.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 KPA45675.1 - 0.024 14.4 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KPA45675.1 - 0.046 14.3 0.4 0.21 12.1 0.0 2.3 2 1 1 3 3 3 0 ABC transporter AAA_16 PF13191.6 KPA45675.1 - 0.11 12.8 0.3 0.56 10.6 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain Phage_HK97_TLTM PF06120.11 KPA45675.1 - 0.22 10.7 3.6 0.23 10.6 0.3 2.2 2 0 0 2 2 2 0 Tail length tape measure protein V-SNARE_C PF12352.8 KPA45676.1 - 0.05 13.9 6.1 0.044 14.1 3.1 2.2 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Usp PF00582.26 KPA45676.1 - 4 7.9 6.5 0.74 10.3 0.5 2.3 1 1 1 2 2 2 0 Universal stress protein family Atg14 PF10186.9 KPA45676.1 - 5.9 5.9 15.4 1 8.4 9.4 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GTP_EFTU PF00009.27 KPA45677.1 - 1.6e-08 34.3 0.0 3.4e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KPA45677.1 - 0.026 14.3 0.1 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rab5ip PF07019.12 KPA45678.1 - 1.5e-28 99.2 5.4 1.7e-28 99.0 5.4 1.0 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) URO-D PF01208.17 KPA45679.1 - 5e-129 430.4 0.0 5.6e-129 430.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF3602 PF12223.8 KPA45680.1 - 4.7e-15 56.0 18.7 1.1e-11 45.2 4.1 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Velvet PF11754.8 KPA45681.1 - 2.4e-90 302.8 0.0 2.4e-90 302.8 0.0 2.6 2 1 0 2 2 2 1 Velvet factor DUF572 PF04502.13 KPA45683.1 - 2.8e-58 198.1 12.7 3.3e-58 197.9 12.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) MDM10 PF12519.8 KPA45683.1 - 0.095 11.6 5.0 0.12 11.3 5.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 BAF1_ABF1 PF04684.13 KPA45683.1 - 0.097 11.7 8.3 0.12 11.5 8.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FB_lectin PF07367.11 KPA45683.1 - 0.1 12.5 0.1 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 Fungal fruit body lectin Kin17_mid PF10357.9 KPA45684.1 - 6.9e-49 164.9 0.4 6.9e-49 164.9 0.4 2.0 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KPA45684.1 - 0.0014 18.9 1.3 0.0014 18.9 1.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPA45684.1 - 0.013 15.8 2.1 0.031 14.7 2.1 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KPA45684.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Ndc1_Nup PF09531.10 KPA45684.1 - 2.4 6.7 9.8 3.2 6.3 9.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt4 PF06093.13 KPA45685.1 - 2.6e-32 110.8 0.3 3.2e-32 110.5 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TBCC PF07986.12 KPA45685.1 - 0.0051 16.5 0.3 0.0063 16.2 0.3 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C PPP5 PF08321.12 KPA45687.1 - 9.9e-33 112.3 0.0 2.5e-32 111.0 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 KPA45687.1 - 2.9e-30 106.3 0.1 4.3e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KPA45687.1 - 3.9e-20 70.7 0.3 8.9e-06 25.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPA45687.1 - 5.2e-14 51.1 0.1 0.0033 17.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KPA45687.1 - 2.1e-12 46.5 1.3 9.2e-05 22.0 0.0 3.4 3 0 0 3 3 3 3 TPR repeat TPR_8 PF13181.6 KPA45687.1 - 3.3e-08 33.1 0.2 0.062 13.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPA45687.1 - 3.9e-06 26.9 0.9 0.28 11.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPA45687.1 - 4.9e-06 27.0 0.0 0.0033 17.9 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KPA45687.1 - 0.0001 22.3 0.0 0.0012 18.9 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPA45687.1 - 0.0011 19.6 0.2 1.4 9.7 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KPA45687.1 - 0.0067 17.2 0.0 17 6.6 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KPA45687.1 - 0.032 14.3 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KPA45687.1 - 0.034 14.4 0.0 4.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KPA45687.1 - 0.086 12.9 0.1 0.46 10.6 0.1 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KPA45687.1 - 0.12 13.0 0.6 7 7.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Es2 PF09751.9 KPA45688.1 - 7.4e-120 401.6 7.7 9e-120 401.3 7.7 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 CN_hydrolase PF00795.22 KPA45689.1 - 1.8e-32 112.8 0.0 2.7e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ABC1 PF03109.16 KPA45689.1 - 2.6e-31 108.2 0.0 6.9e-31 106.9 0.0 1.8 2 0 0 2 2 2 1 ABC1 family NAD_synthase PF02540.17 KPA45689.1 - 2.7e-28 98.7 0.0 6.1e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 NAD synthase Muted PF14942.6 KPA45690.1 - 0.023 15.0 0.9 0.027 14.8 0.9 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein FerA PF08165.11 KPA45690.1 - 0.031 14.2 0.2 0.12 12.3 0.0 2.0 2 1 0 2 2 2 0 FerA (NUC095) domain Flavi_NS5 PF00972.20 KPA45690.1 - 0.081 11.1 0.0 0.086 11.0 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase RRP36 PF06102.12 KPA45691.1 - 9.7e-57 191.5 31.3 1.8e-56 190.7 31.3 1.4 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 DUF1824 PF08854.10 KPA45691.1 - 0.18 11.7 2.6 0.38 10.7 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1824) NIF PF03031.18 KPA45692.1 - 1.7e-19 70.1 0.0 2.3e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EF1G PF00647.19 KPA45693.1 - 5.6e-45 151.8 0.7 1e-44 150.9 0.7 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KPA45693.1 - 2e-13 50.4 2.8 3.7e-13 49.5 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KPA45693.1 - 2.7e-08 34.0 0.0 6.9e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPA45693.1 - 2.5e-06 27.4 0.7 7.7e-06 25.8 0.2 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA45693.1 - 0.00066 19.8 2.1 0.0013 18.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPA45693.1 - 0.0009 19.6 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GET2 PF08690.10 KPA45693.1 - 1.2 8.7 0.0 1.2 8.7 0.0 1.9 2 0 0 2 2 2 0 GET complex subunit GET2 Ribosomal_S9 PF00380.19 KPA45694.1 - 4.7e-41 140.1 0.9 8.2e-41 139.3 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF-hand_1 PF00036.32 KPA45696.1 - 1.2e-26 90.3 13.3 2.4e-07 29.8 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KPA45696.1 - 1.4e-23 83.1 13.4 3e-14 53.2 1.4 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KPA45696.1 - 1.7e-19 68.0 8.2 8.9e-05 22.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KPA45696.1 - 3.5e-18 64.2 10.9 1.7e-06 27.2 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KPA45696.1 - 4.1e-13 49.0 12.3 0.00014 21.7 0.5 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KPA45696.1 - 4.2e-07 30.3 0.1 0.00094 19.5 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KPA45696.1 - 1.9e-06 27.7 7.6 0.0023 17.9 0.5 3.7 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KPA45696.1 - 0.025 14.7 0.7 0.12 12.6 0.7 2.2 1 1 1 2 2 2 0 Dockerin type I domain EF-hand_9 PF14658.6 KPA45696.1 - 0.026 14.8 0.2 4.2 7.8 0.1 3.0 2 1 1 3 3 3 0 EF-hand domain EPL1 PF10513.9 KPA45697.1 - 1e-19 71.5 1.8 1e-19 71.5 1.8 2.9 3 1 0 3 3 3 1 Enhancer of polycomb-like Peptidase_M22 PF00814.25 KPA45698.1 - 9.1e-85 284.6 0.0 1.1e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family AMPKBI PF04739.15 KPA45699.1 - 4.4e-26 91.0 1.4 2.3e-25 88.7 1.4 2.3 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KPA45699.1 - 7.5e-23 80.6 0.0 1.5e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase ABC2_membrane_2 PF12679.7 KPA45700.1 - 0.0079 15.5 6.1 0.0093 15.3 6.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Pkinase PF00069.25 KPA45701.1 - 6.7e-65 219.1 0.0 7.9e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA45701.1 - 1.9e-27 96.2 0.0 2.5e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA45701.1 - 0.0027 17.1 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KPA45701.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase T2SSK PF03934.13 KPA45701.1 - 0.051 13.0 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K Haspin_kinase PF12330.8 KPA45701.1 - 0.074 12.0 0.0 0.18 10.7 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Asparaginase PF00710.20 KPA45702.1 - 9e-59 198.2 0.0 1.8e-58 197.3 0.0 1.5 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KPA45702.1 - 5.5e-26 91.0 0.0 9.2e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KPA45702.1 - 5.2e-10 39.8 0.4 2.1e-09 37.8 0.3 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA45702.1 - 1.5e-08 35.0 0.0 0.00047 20.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA45702.1 - 9.4e-08 31.8 0.2 0.017 15.6 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KPA45702.1 - 6.2e-06 26.4 0.2 0.069 13.6 0.2 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KPA45702.1 - 6.7e-05 23.1 0.2 0.0011 19.3 0.2 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) SLAC1 PF03595.17 KPA45703.1 - 5e-44 150.9 24.4 4e-42 144.6 24.4 2.0 1 1 0 1 1 1 1 Voltage-dependent anion channel TRAP_alpha PF03896.16 KPA45704.1 - 3.8e-10 39.5 0.0 5.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SNF2_N PF00176.23 KPA45705.1 - 4.2e-62 209.9 0.0 6.4e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KPA45705.1 - 1.6e-08 34.3 9.1 3.1e-08 33.3 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA45705.1 - 2.4e-08 34.2 12.0 5.2e-08 33.1 12.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPA45705.1 - 9.6e-08 31.7 12.5 2.2e-07 30.6 12.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA45705.1 - 2.8e-06 27.1 11.5 6.6e-06 25.9 11.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPA45705.1 - 5.9e-06 26.1 10.3 1.3e-05 25.0 10.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Helicase_C PF00271.31 KPA45705.1 - 0.0004 20.7 0.0 0.001 19.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-rbx1 PF12678.7 KPA45705.1 - 0.00057 20.1 9.4 0.0015 18.8 9.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KPA45705.1 - 0.00061 19.7 11.8 0.0012 18.7 11.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPA45705.1 - 0.0011 19.0 7.7 0.0011 18.9 5.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger Baculo_IE-1 PF05290.11 KPA45705.1 - 0.0083 16.1 1.8 0.02 14.9 1.8 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 KPA45705.1 - 0.19 11.6 5.1 0.53 10.1 5.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KPA45705.1 - 0.22 11.7 10.5 0.53 10.5 10.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KPA45705.1 - 0.61 10.0 2.8 1.5 8.7 2.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 KPA45705.1 - 0.63 9.7 7.1 2.1 8.1 7.1 1.9 1 0 0 1 1 1 0 P-11 zinc finger IGR PF09597.10 KPA45706.1 - 6.4e-25 87.0 0.4 1.1e-24 86.3 0.1 1.6 2 0 0 2 2 2 1 IGR protein motif SAM_1 PF00536.30 KPA45706.1 - 0.058 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4661 PF15576.6 KPA45706.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) bZIP_2 PF07716.15 KPA45707.1 - 0.0043 17.1 10.4 0.0076 16.3 10.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KPA45707.1 - 0.54 10.4 9.0 1 9.5 9.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor SMAP PF15477.6 KPA45708.1 - 2.2e-10 41.4 4.0 2.2e-10 41.4 4.0 4.6 3 2 0 3 3 3 1 Small acidic protein family RAMP4 PF06624.12 KPA45709.1 - 3.1e-18 65.6 1.4 3.4e-18 65.4 1.4 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF5090 PF17009.5 KPA45709.1 - 0.064 13.2 0.7 0.077 12.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Mid1 PF12929.7 KPA45711.1 - 3.7e-154 514.0 6.4 4.4e-154 513.8 6.4 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KPA45711.1 - 8e-05 23.2 5.6 0.019 15.5 1.5 2.6 2 0 0 2 2 2 2 Fz domain EcpB_C PF18649.1 KPA45711.1 - 0.12 12.3 0.2 0.12 12.3 0.2 1.9 2 0 0 2 2 2 0 EcpB C-terminal domain TB2_DP1_HVA22 PF03134.19 KPA45712.1 - 7.4e-27 93.1 8.3 1.1e-26 92.5 8.3 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4407 PF14362.6 KPA45712.1 - 0.73 9.1 3.5 0.91 8.8 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) RFX_DNA_binding PF02257.15 KPA45713.1 - 4.6e-28 97.7 0.0 1.3e-27 96.3 0.0 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain AA_kinase PF00696.28 KPA45714.1 - 8.3e-40 136.9 0.5 1.4e-39 136.1 0.0 1.6 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 KPA45714.1 - 6.5e-12 45.0 0.7 1.4e-07 31.1 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KPA45714.1 - 3.6e-11 42.7 4.7 6.4e-09 35.5 0.3 2.4 2 0 0 2 2 2 2 ACT domain Sec10 PF07393.11 KPA45715.1 - 2.6e-164 548.5 0.0 3e-164 548.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KPA45715.1 - 1.3e-07 31.4 0.0 3.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA45715.1 - 2.9e-06 27.0 0.0 5.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KPA45715.1 - 0.028 14.3 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 F-box Pkinase PF00069.25 KPA45716.1 - 2e-63 214.2 0.0 2.5e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA45716.1 - 3.6e-35 121.5 0.0 4.7e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA45716.1 - 0.0014 18.0 0.0 0.0034 16.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KPA45716.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KPA45716.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Frag1 PF10277.9 KPA45718.1 - 2.1e-39 135.3 14.9 2.5e-39 135.1 14.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SUR7 PF06687.12 KPA45718.1 - 0.075 12.7 4.7 1.9 8.1 0.9 2.2 2 0 0 2 2 2 0 SUR7/PalI family MerC PF03203.14 KPA45718.1 - 5.2 7.6 9.5 10 6.6 1.6 2.8 1 1 0 2 2 2 0 MerC mercury resistance protein Eisosome1 PF12757.7 KPA45719.1 - 6.8e-47 158.8 13.2 6.8e-47 158.8 13.2 4.2 2 2 2 4 4 4 1 Eisosome protein 1 Y_phosphatase3 PF13350.6 KPA45720.1 - 7.1e-41 140.7 0.0 1.4e-40 139.7 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KPA45720.1 - 0.00012 21.7 0.0 0.0022 17.6 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 KPA45720.1 - 0.0045 16.0 0.0 0.0076 15.2 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KPA45720.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HTH_Tnp_Tc5 PF03221.16 KPA45721.1 - 0.0019 18.2 1.6 0.006 16.6 0.1 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain T3SS_ATPase_C PF18269.1 KPA45722.1 - 0.015 15.1 0.5 0.39 10.6 0.1 2.3 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain DUF737 PF05300.11 KPA45722.1 - 0.019 15.3 6.1 0.021 15.2 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Troponin PF00992.20 KPA45722.1 - 0.075 13.3 8.1 0.25 11.6 5.5 2.1 1 1 1 2 2 2 0 Troponin Exonuc_VII_L PF02601.15 KPA45722.1 - 0.097 12.2 5.7 0.11 12.0 5.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MCPsignal PF00015.21 KPA45722.1 - 0.11 12.3 3.3 0.14 12.0 3.3 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LCIB_C_CA PF18599.1 KPA45722.1 - 0.28 10.4 1.6 0.35 10.1 1.3 1.3 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Tup_N PF08581.10 KPA45722.1 - 0.74 10.2 7.9 0.77 10.1 1.6 2.3 2 0 0 2 2 2 0 Tup N-terminal APH PF01636.23 KPA45723.1 - 6.5e-13 49.2 0.0 1.3e-12 48.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPA45723.1 - 0.0049 16.5 0.0 0.0096 15.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase YnfE PF17452.2 KPA45723.1 - 0.16 12.3 0.1 0.61 10.4 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized YnfE-like Ribosomal_L15e PF00827.17 KPA45724.1 - 4.4e-88 294.0 10.6 4.4e-88 294.0 10.6 1.8 2 0 0 2 2 2 1 Ribosomal L15 Rad51 PF08423.11 KPA45725.1 - 7e-46 156.6 0.0 2.5e-45 154.7 0.0 1.7 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KPA45725.1 - 7.8e-08 32.1 0.3 7.8e-07 28.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain RecA PF00154.21 KPA45725.1 - 5.1e-06 26.2 0.1 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 KPA45725.1 - 0.00029 20.3 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.6 KPA45725.1 - 0.032 14.6 0.6 0.071 13.5 0.1 1.8 2 1 0 2 2 2 0 AAA ATPase domain RNA_pol_Rpb2_6 PF00562.28 KPA45726.1 - 1.1e-120 403.3 0.0 1.9e-120 402.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KPA45726.1 - 6.5e-55 185.8 0.1 1.1e-54 185.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KPA45726.1 - 2.2e-33 114.5 0.9 4.9e-33 113.4 0.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KPA45726.1 - 8e-29 100.6 0.1 2.2e-28 99.2 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KPA45726.1 - 7.1e-22 77.5 0.2 1.9e-21 76.1 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KPA45726.1 - 3.3e-19 68.8 0.0 6.6e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KPA45726.1 - 1.8e-10 41.2 0.6 7.6e-10 39.2 0.6 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PUF PF00806.19 KPA45728.1 - 1.1e-56 185.5 14.1 1.1e-07 31.2 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Carn_acyltransf PF00755.20 KPA45729.1 - 4.9e-208 692.5 0.0 1.5e-207 690.9 0.0 1.7 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase MFS_1 PF07690.16 KPA45730.1 - 2.5e-34 118.8 52.3 6.5e-32 110.8 51.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA45730.1 - 7.1e-08 31.3 7.7 7.1e-08 31.3 7.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HSP70 PF00012.20 KPA45732.1 - 9.4e-258 856.3 5.4 1.1e-257 856.2 5.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KPA45732.1 - 6.7e-17 61.3 0.0 4e-16 58.8 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KPA45732.1 - 0.0065 16.2 0.0 0.027 14.2 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KPA45732.1 - 0.012 14.9 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.6 KPA45732.1 - 0.032 14.6 1.5 8.6 6.8 0.1 3.3 3 2 0 3 3 3 0 Cell division protein FtsA StbA PF06406.11 KPA45732.1 - 0.04 13.2 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 StbA protein Actin PF00022.19 KPA45732.1 - 0.17 10.5 3.0 0.63 8.6 0.0 2.5 2 1 0 3 3 3 0 Actin DUF3128 PF11326.8 KPA45733.1 - 2.2e-27 95.2 2.4 2.2e-27 95.2 2.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) GET2 PF08690.10 KPA45733.1 - 2.8 7.5 6.4 3.5 7.2 6.4 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 RNA12 PF10443.9 KPA45734.1 - 8.1e-156 519.2 0.3 1.6e-155 518.2 0.1 1.6 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.22 KPA45734.1 - 1.8e-06 27.7 0.0 8.7e-06 25.5 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 KPA45734.1 - 1.8e-05 24.8 0.1 0.00016 21.7 0.1 2.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2487 PF10673.9 KPA45734.1 - 0.0045 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) Mif2_N PF15624.6 KPA45735.1 - 5.7e-35 121.0 6.7 5.7e-35 121.0 6.7 3.5 2 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 KPA45735.1 - 2.3e-33 114.3 0.1 3.5e-33 113.7 0.1 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KPA45735.1 - 2.4e-05 24.0 0.0 5.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KPA45735.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RNase_HII PF01351.18 KPA45736.1 - 1.8e-46 158.5 0.0 2.3e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII RHD3 PF05879.12 KPA45737.1 - 0 1028.1 0.0 0 1027.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KPA45737.1 - 3e-07 30.0 0.1 5e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KPA45737.1 - 1.8e-06 28.1 0.3 4.3e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KPA45737.1 - 0.00013 22.0 0.0 0.00034 20.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KPA45737.1 - 0.0018 18.5 0.4 0.0055 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 KPA45737.1 - 0.046 13.0 0.1 0.087 12.1 0.1 1.4 1 0 0 1 1 1 0 Septin DLH PF01738.18 KPA45738.1 - 1e-24 87.3 0.0 1.4e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KPA45738.1 - 0.0044 16.7 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KPA45738.1 - 0.041 13.8 0.0 0.097 12.6 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cadherin_5 PF17892.1 KPA45738.1 - 0.095 12.7 0.1 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Cadherin-like domain MS_channel PF00924.18 KPA45739.1 - 1e-18 67.7 2.6 1.9e-18 66.8 2.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.6 KPA45739.1 - 0.1 13.1 0.3 0.32 11.5 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 KPA45739.1 - 0.15 11.7 1.5 0.42 10.3 1.5 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KPA45739.1 - 0.38 10.8 2.8 0.63 10.1 0.3 2.7 3 0 0 3 3 3 0 EF-hand domain E1-E2_ATPase PF00122.20 KPA45739.1 - 2.6 7.6 5.1 21 4.5 0.1 2.4 2 0 0 2 2 2 0 E1-E2 ATPase Sugar_tr PF00083.24 KPA45740.1 - 3.9e-91 306.2 19.2 5e-91 305.8 19.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA45740.1 - 1.9e-13 50.1 44.5 2.7e-10 39.7 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abp2 PF09441.10 KPA45741.1 - 1.4e-80 269.3 0.0 2.3e-80 268.7 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 TMF_TATA_bd PF12325.8 KPA45741.1 - 0.39 11.0 0.9 0.77 10.0 0.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LBP_C PF17386.2 KPA45742.1 - 0.036 13.9 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase C-terminal domain Sds3 PF08598.11 KPA45743.1 - 4.4e-26 92.2 7.5 6.5e-26 91.7 7.5 1.3 1 0 0 1 1 1 1 Sds3-like Amidinotransf PF02274.17 KPA45743.1 - 0.073 12.2 0.2 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Amidinotransferase COG5 PF10392.9 KPA45744.1 - 0.014 15.6 3.7 0.022 15.0 0.1 2.8 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Ku_PK_bind PF08785.11 KPA45744.1 - 0.025 14.7 1.5 0.025 14.7 1.5 1.9 3 0 0 3 3 3 0 Ku C terminal domain like 2CSK_N PF08521.10 KPA45744.1 - 0.059 13.5 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal Baculo_PEP_C PF04513.12 KPA45744.1 - 0.074 13.1 4.0 0.091 12.8 1.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF572 PF04502.13 KPA45744.1 - 1.7 8.2 5.8 0.75 9.4 1.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF3486 PF11985.8 KPA45744.1 - 3 8.2 10.4 0.29 11.5 0.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3486) Ala_racemase_N PF01168.20 KPA45745.1 - 2.5e-22 79.6 0.0 3e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 KPA45746.1 - 2.3e-122 409.2 10.1 2.8e-122 409.0 10.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KPA45746.1 - 7.1e-47 158.3 0.0 1.9e-46 156.9 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KPA45746.1 - 8.8e-15 55.0 0.0 1.8e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain AP4E_app_platf PF14807.6 KPA45746.1 - 0.0028 18.0 0.0 0.01 16.2 0.0 2.0 2 0 0 2 2 2 1 Adaptin AP4 complex epsilon appendage platform RTP1_C1 PF10363.9 KPA45746.1 - 0.012 15.8 0.2 0.052 13.7 0.2 2.2 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KPA45746.1 - 0.077 12.5 0.5 0.23 11.0 0.5 1.9 1 0 0 1 1 1 0 CLASP N terminal Methyltransf_23 PF13489.6 KPA45747.1 - 5.6e-10 39.3 0.0 9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA45747.1 - 1.5e-09 38.4 0.0 3.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA45747.1 - 2.8e-08 34.4 0.0 4.7e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA45747.1 - 2e-07 31.6 0.0 6.7e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA45747.1 - 0.00015 21.6 0.0 0.00068 19.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA45747.1 - 0.041 13.2 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family P16-Arc PF04699.14 KPA45748.1 - 3.9e-52 176.7 0.0 4.6e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) PSP1 PF04468.12 KPA45749.1 - 1.3e-28 99.1 1.2 2.4e-28 98.2 1.2 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region WD40 PF00400.32 KPA45750.1 - 6.1e-20 71.2 6.3 6.5e-05 23.6 0.0 8.9 10 0 0 10 10 10 4 WD domain, G-beta repeat SUR7 PF06687.12 KPA45751.1 - 7.3e-30 104.2 2.8 9.2e-30 103.8 2.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 KPA45751.1 - 0.23 11.3 4.5 0.051 13.4 1.1 1.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) HSP70 PF00012.20 KPA45752.1 - 1.4e-07 30.1 0.0 1.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein Lysine_decarbox PF03641.14 KPA45752.1 - 0.055 13.6 0.0 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 Possible lysine decarboxylase MreB_Mbl PF06723.13 KPA45752.1 - 0.086 11.6 0.0 0.53 9.0 0.0 2.2 3 0 0 3 3 3 0 MreB/Mbl protein CdvA PF18822.1 KPA45753.1 - 0.003 17.4 0.7 0.04 13.7 0.5 2.4 2 0 0 2 2 2 1 CdvA-like coiled-coil domain Prefoldin_2 PF01920.20 KPA45753.1 - 0.012 15.5 1.4 0.16 12.0 2.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit Takusan PF04822.13 KPA45753.1 - 0.014 15.3 0.3 0.035 14.0 0.3 1.7 1 0 0 1 1 1 0 Takusan TEX13 PF15186.6 KPA45753.1 - 0.016 14.9 1.6 0.037 13.7 1.6 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Phage_GP20 PF06810.11 KPA45753.1 - 0.073 12.9 1.6 0.15 11.9 1.6 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 FAD-SLDH PF12318.8 KPA45753.1 - 0.081 13.0 0.7 0.2 11.7 0.7 1.6 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase GTP-bdg_M PF16360.5 KPA45753.1 - 0.88 10.2 5.1 0.62 10.7 2.3 2.1 2 1 0 2 2 2 0 GTP-binding GTPase Middle Region Med21 PF11221.8 KPA45753.1 - 1.3 9.2 7.0 0.44 10.8 1.7 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Spc7 PF08317.11 KPA45753.1 - 1.5 7.6 8.8 0.62 8.9 3.9 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 KPA45753.1 - 2.1 9.0 5.2 6.9 7.4 1.9 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Metallophos PF00149.28 KPA45754.1 - 1e-34 120.8 0.7 1.6e-34 120.2 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KPA45754.1 - 4.6e-17 62.2 0.0 9.5e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain RRM_3 PF08777.11 KPA45755.1 - 0.021 14.8 0.2 0.039 14.0 0.2 1.3 1 0 0 1 1 1 0 RNA binding motif Aldedh PF00171.22 KPA45756.1 - 7e-166 552.3 0.1 7e-166 552.3 0.1 1.4 2 0 0 2 2 2 1 Aldehyde dehydrogenase family RRF PF01765.19 KPA45756.1 - 2.1e-31 109.1 4.1 2.1e-31 109.1 4.1 1.8 2 0 0 2 2 2 1 Ribosome recycling factor SWI-SNF_Ssr4 PF08549.10 KPA45756.1 - 0.092 11.4 6.6 0.15 10.7 6.6 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) ATP-synt_B PF00430.18 KPA45756.1 - 0.4 10.8 6.5 1 9.4 6.5 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) HATPase_c PF02518.26 KPA45757.1 - 7.8e-22 77.9 0.2 1.6e-21 76.9 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPA45757.1 - 6e-21 74.7 0.1 1.2e-20 73.8 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 KPA45757.1 - 1.4e-09 38.2 0.0 0.0013 19.0 0.0 2.9 3 0 0 3 3 3 2 PAS fold HisKA PF00512.25 KPA45757.1 - 1.9e-06 27.8 1.2 2.9e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KPA45757.1 - 3.6e-06 27.2 0.1 0.00013 22.2 0.0 2.9 2 1 0 2 2 2 1 PAS domain PAS PF00989.25 KPA45757.1 - 8.6e-05 22.5 0.1 0.00054 19.9 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 KPA45757.1 - 0.00031 20.7 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 PAS domain GAF_2 PF13185.6 KPA45757.1 - 0.00033 21.0 0.0 0.91 9.8 0.0 2.8 2 0 0 2 2 2 2 GAF domain PAS_3 PF08447.12 KPA45757.1 - 0.0015 18.8 3.6 0.0027 17.9 0.1 3.0 4 0 0 4 4 4 1 PAS fold GAF_3 PF13492.6 KPA45757.1 - 0.013 15.9 0.0 0.039 14.3 0.0 1.8 2 0 0 2 2 2 0 GAF domain PH_6 PF15406.6 KPA45758.1 - 2.5e-44 150.1 1.2 2.5e-44 150.1 1.2 3.4 4 0 0 4 4 4 1 Pleckstrin homology domain PH PF00169.29 KPA45758.1 - 0.0026 18.3 0.0 0.0081 16.7 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KPA45758.1 - 0.1 12.4 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Ribosomal_L36 PF00444.18 KPA45760.1 - 2.3e-21 75.7 11.5 2.9e-21 75.4 11.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 Complex1_LYR PF05347.15 KPA45761.1 - 1.5e-18 66.6 0.1 2.1e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KPA45761.1 - 9.5e-07 29.5 0.0 1.4e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like PLAC8 PF04749.17 KPA45762.1 - 2.7e-24 86.0 15.5 3.5e-24 85.7 15.5 1.1 1 0 0 1 1 1 1 PLAC8 family IMPDH PF00478.25 KPA45763.1 - 1.8e-127 425.1 2.8 2.1e-127 424.9 2.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KPA45763.1 - 4e-16 59.2 0.1 1.2e-07 32.0 0.1 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KPA45763.1 - 6.9e-07 28.6 0.5 1.9e-06 27.2 0.4 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KPA45763.1 - 1.4e-06 28.0 3.3 0.014 14.8 3.2 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KPA45763.1 - 0.00044 19.8 2.0 0.063 12.7 0.1 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein YpsA PF06908.11 KPA45763.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family PK PF00224.21 KPA45763.1 - 0.037 12.9 0.0 0.11 11.4 0.0 1.7 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain ThiG PF05690.14 KPA45763.1 - 0.059 12.7 1.6 0.31 10.3 0.3 2.5 1 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG Raffinose_syn PF05691.12 KPA45764.1 - 6.6e-53 179.6 5.9 4e-51 173.7 2.5 2.7 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 Peptidase_M16 PF00675.20 KPA45765.1 - 3.5e-58 195.8 0.4 7.8e-58 194.7 0.4 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KPA45765.1 - 1.7e-38 132.5 0.0 5.1e-38 130.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Esterase PF00756.20 KPA45765.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Putative esterase RbsD_FucU PF05025.13 KPA45765.1 - 0.067 13.6 0.2 0.51 10.8 0.1 2.3 2 0 0 2 2 2 0 RbsD / FucU transport protein family TFIID-31kDa PF02291.15 KPA45766.1 - 2.5e-42 143.8 0.0 3.3e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Mucin PF01456.17 KPA45766.1 - 2.8 7.9 16.6 0.082 12.9 10.5 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Histidinol_dh PF00815.20 KPA45767.1 - 2.5e-158 527.4 4.8 3.4e-158 526.9 4.8 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KPA45767.1 - 4.7e-23 80.8 0.0 9.8e-23 79.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KPA45767.1 - 7.2e-13 48.8 0.2 1.7e-12 47.6 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase LNS2 PF08235.13 KPA45768.1 - 5.7e-93 310.5 0.0 7.9e-93 310.1 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KPA45768.1 - 1.4e-41 140.5 0.0 3.3e-41 139.4 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KPA45768.1 - 0.0075 15.9 0.0 0.44 10.1 0.0 2.6 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.21 KPA45769.1 - 8.1e-10 38.9 0.1 2.3e-09 37.5 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain APG6_N PF17675.1 KPA45769.1 - 7.2 7.1 64.4 1.2 9.7 19.7 3.7 1 1 2 3 3 3 0 Apg6 coiled-coil region Lebercilin PF15619.6 KPA45769.1 - 7.4 6.2 50.7 3 7.5 0.9 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Vps53_N PF04100.12 KPA45770.1 - 5.5e-107 358.0 1.1 1e-106 357.1 1.1 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 KPA45770.1 - 3.2e-06 26.7 5.9 5.8e-06 25.8 5.9 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KPA45770.1 - 0.00014 21.8 0.3 0.00037 20.4 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.13 KPA45770.1 - 0.0013 17.7 2.1 0.22 10.4 0.0 3.2 3 1 0 3 3 3 2 RINT-1 / TIP-1 family Zw10 PF06248.13 KPA45770.1 - 0.0028 16.3 4.2 0.0066 15.1 4.2 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Spc7 PF08317.11 KPA45770.1 - 0.024 13.5 4.3 0.05 12.5 4.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein FliG_N PF14842.6 KPA45770.1 - 0.029 14.9 0.3 0.27 11.8 0.1 2.8 2 0 0 2 2 2 0 FliG N-terminal domain UPF0175 PF03683.13 KPA45770.1 - 0.045 13.5 0.1 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) VPS53_C PF16854.5 KPA45770.1 - 0.05 13.5 0.0 0.47 10.3 0.0 2.4 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus CENP-R PF06729.12 KPA45770.1 - 0.055 13.4 1.8 0.14 12.1 1.8 1.6 1 0 0 1 1 1 0 Kinetochore component, CENP-R DUF5082 PF16888.5 KPA45770.1 - 0.26 11.6 3.6 0.56 10.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) COG2 PF06148.11 KPA45770.1 - 2.3 8.3 5.8 9 6.4 3.3 3.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Pyr_redox_2 PF07992.14 KPA45771.1 - 2.9e-46 158.1 0.6 3.4e-46 157.8 0.6 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA45771.1 - 4.2e-18 65.6 0.6 1.3e-16 60.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPA45771.1 - 4.1e-15 56.1 0.2 1.3e-12 48.1 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KPA45771.1 - 8.9e-05 22.9 0.0 0.045 14.2 0.0 2.8 2 2 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KPA45771.1 - 0.00022 20.6 0.1 0.00057 19.2 0.1 1.7 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KPA45771.1 - 0.00046 20.4 0.2 0.053 13.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPA45771.1 - 0.0015 17.8 0.1 0.33 10.0 0.0 3.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KPA45771.1 - 0.0042 16.7 0.9 1.2 8.6 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KPA45771.1 - 0.0088 15.4 0.2 0.052 12.9 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KPA45771.1 - 0.02 14.0 3.5 0.42 9.6 0.3 3.4 3 1 1 4 4 4 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KPA45771.1 - 0.11 11.6 5.4 0.22 10.5 0.4 2.8 2 1 2 4 4 4 0 FAD binding domain Shikimate_DH PF01488.20 KPA45771.1 - 0.14 12.3 0.0 14 5.8 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 KPA45771.1 - 0.14 11.0 0.1 0.47 9.2 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase UDPGP PF01704.18 KPA45772.1 - 2e-54 184.9 0.0 2.4e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase UDG PF03167.19 KPA45773.1 - 1.4e-21 77.1 0.0 2.2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Actin PF00022.19 KPA45774.1 - 7.5e-153 508.9 0.0 8.5e-153 508.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KPA45774.1 - 1.1e-06 27.7 0.0 0.0048 15.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein tRNA-synt_2 PF00152.20 KPA45775.1 - 1.2e-62 211.8 0.0 2.4e-51 174.7 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KPA45775.1 - 1.5e-09 37.7 0.2 2.9e-09 36.8 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KPA45775.1 - 2.6e-05 23.9 0.0 0.012 15.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SpoU_methylas_C PF12105.8 KPA45775.1 - 0.13 11.9 0.9 3.3 7.5 0.2 2.5 2 0 0 2 2 2 0 SpoU, rRNA methylase, C-terminal FSAP_sig_propep PF03032.15 KPA45775.1 - 0.58 10.2 3.4 1.9 8.6 3.4 1.9 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide DUF2401 PF10287.9 KPA45776.1 - 6.7e-92 307.2 1.9 6.7e-92 307.2 1.9 1.5 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 KPA45776.1 - 4.4e-22 78.3 0.0 1.2e-21 76.9 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Helicase_C PF00271.31 KPA45777.1 - 3.6e-25 88.5 0.0 9.7e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPA45777.1 - 2.3e-24 86.1 0.0 1.8e-23 83.2 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KPA45777.1 - 3.8e-05 23.7 0.2 0.00011 22.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIA PF03153.13 KPA45777.1 - 6.8 6.6 12.3 22 4.9 12.3 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMS19_C PF12460.8 KPA45779.1 - 0.045 12.9 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal CorA PF01544.18 KPA45781.1 - 3e-11 43.2 0.1 5.7e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Vps8 PF12816.7 KPA45782.1 - 2.1e-73 246.1 0.0 4.7e-73 244.9 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 PIG-P PF08510.12 KPA45782.1 - 1.3e-51 173.6 0.9 3.1e-51 172.4 0.9 1.7 1 0 0 1 1 1 1 PIG-P Clathrin PF00637.20 KPA45782.1 - 3.6e-05 23.7 0.1 0.032 14.1 0.0 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS DPM2 PF07297.12 KPA45782.1 - 0.15 12.4 9.5 0.35 11.2 9.5 1.6 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF3752 PF12572.8 KPA45783.1 - 6.7e-50 169.5 11.1 6.7e-50 169.5 11.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Barttin PF15462.6 KPA45783.1 - 1.6 8.4 9.5 0.17 11.7 4.5 1.8 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) zf-RING_2 PF13639.6 KPA45784.1 - 1e-11 45.0 6.7 1.6e-11 44.3 6.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPA45784.1 - 5.7e-08 32.5 6.4 9.2e-08 31.8 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA45784.1 - 6.6e-08 32.3 3.8 1.2e-07 31.5 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPA45784.1 - 7.2e-08 32.0 0.9 1.3e-07 31.3 0.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KPA45784.1 - 1e-06 28.9 8.3 3.7e-06 27.1 8.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KPA45784.1 - 9.1e-06 25.5 3.7 1.5e-05 24.9 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KPA45784.1 - 0.002 18.1 5.2 0.0066 16.5 5.2 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KPA45784.1 - 0.0029 17.6 0.9 0.0029 17.6 0.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KPA45784.1 - 0.0033 17.2 2.9 0.0059 16.4 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KPA45784.1 - 0.02 14.7 6.5 0.041 13.7 6.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KPA45784.1 - 0.13 12.1 4.0 0.28 11.1 4.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 KPA45784.1 - 0.22 11.5 6.0 0.42 10.5 6.0 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KPA45784.1 - 0.41 10.3 4.5 0.72 9.5 4.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KPA45784.1 - 0.56 10.4 3.6 1.7 8.9 3.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain OAD_gamma PF04277.13 KPA45784.1 - 0.77 10.4 0.0 0.77 10.4 0.0 4.3 4 2 0 4 4 3 0 Oxaloacetate decarboxylase, gamma chain zf-C3HC4_4 PF15227.6 KPA45784.1 - 0.87 9.8 4.6 1.9 8.7 4.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pro_isomerase PF00160.21 KPA45785.1 - 2.1e-49 167.8 0.2 2.4e-49 167.7 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TEA PF01285.18 KPA45786.1 - 4e-27 94.1 0.0 9.1e-27 92.9 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain RRM_1 PF00076.22 KPA45787.1 - 1e-74 246.3 0.2 3.9e-19 68.2 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPA45787.1 - 2.2e-08 33.8 0.0 0.21 11.4 0.0 4.7 5 0 0 5 5 5 3 Occluded RNA-recognition motif RRM_7 PF16367.5 KPA45787.1 - 3.2e-05 24.0 0.0 1.1 9.4 0.0 3.9 3 0 0 3 3 3 2 RNA recognition motif RRM_Rrp7 PF17799.1 KPA45787.1 - 9.2e-05 22.3 0.1 23 4.8 0.0 4.7 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 KPA45787.1 - 0.0001 22.3 0.1 6.1 7.0 0.0 5.3 5 1 0 5 5 5 1 Limkain b1 Smg4_UPF3 PF03467.15 KPA45787.1 - 0.044 13.8 5.4 0.29 11.2 0.0 4.1 4 1 0 4 4 4 0 Smg-4/UPF3 family PHM7_cyt PF14703.6 KPA45787.1 - 0.052 13.8 2.4 4.2 7.6 0.1 4.3 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KPA45787.1 - 0.056 13.4 0.0 5.3 7.1 0.0 3.5 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.12 KPA45787.1 - 0.072 13.3 0.0 28 5.0 0.0 3.0 2 0 0 2 2 2 0 RNA recognition motif 2 Dynein_light PF01221.18 KPA45788.1 - 4e-39 132.8 1.3 4.9e-39 132.5 1.3 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 SGTA_dimer PF16546.5 KPA45788.1 - 0.076 12.8 0.5 0.11 12.2 0.5 1.2 1 0 0 1 1 1 0 Homodimerisation domain of SGTA Methyltransf_16 PF10294.9 KPA45791.1 - 6.8e-20 71.5 0.0 1.4e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KPA45791.1 - 0.043 13.6 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF4599 PF15371.6 KPA45791.1 - 0.37 11.4 1.3 0.69 10.5 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) KIND PF16474.5 KPA45793.1 - 1.6 8.6 6.5 2 8.3 0.6 2.7 2 1 0 2 2 2 0 Kinase non-catalytic C-lobe domain Fer4_13 PF13370.6 KPA45793.1 - 7.9 7.1 6.5 40 4.9 0.3 3.8 3 1 1 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I RNA_pol_N PF01194.17 KPA45794.1 - 2.1e-29 101.6 1.0 2.6e-29 101.3 1.0 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KPA45794.1 - 0.021 15.1 0.2 0.034 14.4 0.2 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) WD40 PF00400.32 KPA45795.1 - 5.7e-09 36.5 8.6 0.018 15.9 0.1 5.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA45795.1 - 4.9e-06 26.8 1.4 0.5 10.7 0.1 5.2 4 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DIOX_N PF14226.6 KPA45796.1 - 7.5e-34 117.0 0.0 3.8e-32 111.5 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPA45796.1 - 2.1e-11 44.2 0.0 4.3e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GxGYxYP_C PF14323.6 KPA45796.1 - 0.061 13.2 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain Taq-exonuc PF09281.10 KPA45796.1 - 0.08 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Taq polymerase, exonuclease zf-met2 PF12907.7 KPA45797.1 - 9.2e-17 60.9 4.5 9.2e-17 60.9 4.5 1.6 2 0 0 2 2 2 1 Zinc-binding 4F5 PF04419.14 KPA45797.1 - 1.2e-05 26.1 10.2 1.2e-05 26.1 10.2 2.0 2 0 0 2 2 2 1 4F5 protein family DUF382 PF04037.13 KPA45797.1 - 0.025 14.7 0.3 0.029 14.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF382) FAD_binding_4 PF01565.23 KPA45798.1 - 6.7e-20 71.3 3.5 6.7e-20 71.3 3.5 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KPA45798.1 - 1.2e-07 31.8 0.3 2.5e-07 30.7 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KPA45798.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding HHH PF00633.23 KPA45799.1 - 0.025 14.5 0.1 0.058 13.3 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF1479 PF07350.12 KPA45800.1 - 2.5e-142 474.5 0.0 2.9e-142 474.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Bap31 PF05529.12 KPA45801.1 - 1.1e-49 167.8 7.3 1.5e-49 167.3 7.3 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KPA45801.1 - 6.4e-13 48.5 6.2 1.1e-12 47.7 6.2 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Mod_r PF07200.13 KPA45801.1 - 0.013 15.6 2.7 0.021 15.0 2.7 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein V_ATPase_I PF01496.19 KPA45801.1 - 0.015 13.3 1.6 0.021 12.8 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Wtap PF17098.5 KPA45801.1 - 0.022 14.7 3.0 0.035 14.0 3.0 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family TolA_bind_tri PF16331.5 KPA45801.1 - 0.044 13.9 1.1 0.11 12.5 1.1 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF192 PF02643.15 KPA45801.1 - 0.05 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 DUF2730 PF10805.8 KPA45801.1 - 0.052 13.6 0.5 0.1 12.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Spc7 PF08317.11 KPA45801.1 - 0.067 12.1 4.6 0.093 11.6 4.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 KPA45801.1 - 0.072 13.6 4.9 0.14 12.7 4.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DHR10 PF18595.1 KPA45801.1 - 0.13 12.4 7.7 0.24 11.5 7.5 1.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Prefoldin PF02996.17 KPA45801.1 - 0.31 11.0 4.1 0.38 10.7 1.7 2.0 1 1 1 2 2 2 0 Prefoldin subunit DivIC PF04977.15 KPA45801.1 - 0.38 10.5 9.3 0.76 9.6 2.8 3.2 4 0 0 4 4 4 0 Septum formation initiator UPF0242 PF06785.11 KPA45801.1 - 3.5 7.7 7.7 0.11 12.6 1.0 1.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 KPA45801.1 - 4.3 7.7 8.5 1.1 9.6 4.5 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain EZH2_N PF18601.1 KPA45802.1 - 4.2e-37 126.3 7.3 6.1e-37 125.8 5.9 2.1 2 0 0 2 2 2 1 EZH2 N-terminal domain Ezh2_MCSS PF18600.1 KPA45802.1 - 1.8e-24 85.1 0.9 4e-24 84.0 0.9 1.6 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 KPA45802.1 - 5.9e-14 52.8 0.1 5.9e-14 52.8 0.1 3.5 4 2 0 4 4 4 1 SET domain preSET_CXC PF18264.1 KPA45802.1 - 4.3e-06 27.1 14.8 4.3e-06 27.1 14.8 3.2 2 1 0 3 3 3 1 CXC domain PYST-C1 PF09690.10 KPA45802.1 - 1.2 9.0 12.5 1.7 8.4 1.4 2.7 2 0 0 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) Importin_rep_4 PF18808.1 KPA45802.1 - 2 8.7 7.5 7.9 6.8 7.5 2.0 1 0 0 1 1 1 0 Importin repeat Pil1 PF13805.6 KPA45803.1 - 1.2e-124 415.1 0.4 1.4e-124 414.8 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 T3SSipB PF16535.5 KPA45803.1 - 0.1 13.0 1.1 0.26 11.7 1.0 1.7 1 1 0 1 1 1 0 Type III cell invasion protein SipB FAM92 PF06730.11 KPA45803.1 - 0.35 10.2 4.3 0.23 10.9 1.5 1.9 1 1 0 2 2 2 0 FAM92 protein APG6_N PF17675.1 KPA45803.1 - 7.8 7.0 10.1 36 4.9 3.6 3.0 1 1 0 2 2 2 0 Apg6 coiled-coil region LSM PF01423.22 KPA45804.1 - 3.1e-11 42.8 0.0 4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KPA45804.1 - 0.062 13.4 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain XPG_N PF00752.17 KPA45805.1 - 2.7e-34 117.6 0.1 8.1e-34 116.1 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KPA45805.1 - 6.3e-28 97.0 0.0 1.9e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 KPA45805.1 - 0.00048 19.9 1.6 0.00048 19.9 1.6 3.1 2 0 0 2 2 2 1 Ubiquitin interaction motif 5_3_exonuc PF01367.20 KPA45805.1 - 0.099 13.3 0.0 0.35 11.5 0.0 1.9 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TFIIS_M PF07500.14 KPA45806.1 - 1.1e-29 103.2 2.3 1.1e-29 103.2 2.3 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KPA45806.1 - 5.9e-17 61.2 7.5 9.7e-17 60.5 7.5 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KPA45806.1 - 5.1e-12 45.6 0.3 5.1e-12 45.6 0.3 3.2 4 1 0 4 4 4 1 TFIIS helical bundle-like domain PALP PF00291.25 KPA45807.1 - 5.6e-63 213.1 0.7 6.7e-63 212.8 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.17 KPA45808.1 - 4.8e-38 131.3 0.0 6.9e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KPA45808.1 - 0.0058 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase tRNA-synt_2c PF01411.19 KPA45809.1 - 9.8e-215 714.2 0.1 1.7e-214 713.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KPA45809.1 - 5.3e-17 61.6 0.1 1.6e-16 60.1 0.1 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KPA45809.1 - 1.7e-08 34.9 1.9 1.7e-08 34.9 1.9 2.8 2 1 1 3 3 3 1 DHHA1 domain EF-hand_7 PF13499.6 KPA45809.1 - 0.67 10.5 4.6 6.6 7.3 0.1 3.7 4 1 0 4 4 4 0 EF-hand domain pair RCR PF12273.8 KPA45811.1 - 5.1e-11 43.3 14.4 1.1e-10 42.2 14.4 1.7 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4381 PF14316.6 KPA45811.1 - 0.049 13.9 0.6 0.074 13.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Sel1 PF08238.12 KPA45812.1 - 1.6e-35 120.8 32.8 0.0001 22.9 0.0 13.0 13 1 1 14 14 14 9 Sel1 repeat TPR_17 PF13431.6 KPA45812.1 - 0.0066 16.8 6.6 13 6.5 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KPA45812.1 - 0.0067 17.0 10.9 35 5.3 0.2 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 KPA45812.1 - 0.085 13.1 0.4 1.1 9.7 0.2 3.0 2 0 0 2 2 2 0 PPR repeat SNAP PF14938.6 KPA45812.1 - 0.16 11.3 1.9 0.72 9.2 0.0 2.8 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KPA45812.1 - 0.62 10.2 9.4 2.8 8.2 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 KPA45812.1 - 0.84 10.2 10.3 1.9 9.0 0.6 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1708 PF08101.11 KPA45813.1 - 4.5e-177 589.6 0.0 6.3e-177 589.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DP PF08781.10 KPA45813.1 - 0.29 11.0 2.4 16 5.4 0.1 2.5 2 0 0 2 2 2 0 Transcription factor DP UDG PF03167.19 KPA45814.1 - 2.6e-24 86.0 0.0 4.5e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF726 PF05277.12 KPA45815.1 - 2.7e-115 385.0 0.2 3.5e-115 384.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KPA45815.1 - 0.0038 17.4 5.0 0.0042 17.2 0.0 3.1 4 0 0 4 4 4 1 Thioesterase domain Abhydrolase_9 PF10081.9 KPA45815.1 - 0.026 13.6 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family PE-PPE PF08237.11 KPA45815.1 - 0.098 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_6 PF12697.7 KPA45815.1 - 8.7 6.9 8.8 0.19 12.3 0.6 2.2 2 1 1 3 3 3 0 Alpha/beta hydrolase family ThylakoidFormat PF11264.8 KPA45815.1 - 8.8 6.0 7.7 0.3 10.8 0.1 2.0 2 0 0 2 2 2 0 Thylakoid formation protein GAGA_bind PF06217.12 KPA45816.1 - 0.047 14.0 11.9 0.062 13.6 11.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family GREB1 PF15782.5 KPA45816.1 - 0.38 7.8 8.4 0.36 7.9 8.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 KPA45816.1 - 1.9 6.5 14.3 2.1 6.4 14.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AAA_11 PF13086.6 KPA45816.1 - 4.1 7.1 15.0 5.4 6.7 15.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 KPA45816.1 - 6.6 6.0 11.0 6.9 5.9 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.22 KPA45816.1 - 8.2 5.5 9.3 12 5.0 9.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CRT10 PF08728.10 KPA45816.1 - 8.6 4.4 11.9 10 4.1 11.9 1.0 1 0 0 1 1 1 0 CRT10 SAPS PF04499.15 KPA45816.1 - 9.7 4.8 12.1 11 4.6 12.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Thg1 PF04446.12 KPA45817.1 - 9.1e-54 180.8 0.0 1.4e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KPA45817.1 - 1.3e-49 167.4 3.0 1.9e-49 166.9 3.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Tipalpha PF16753.5 KPA45817.1 - 0.062 13.1 0.2 2.3 8.0 0.1 2.2 2 0 0 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter WD40 PF00400.32 KPA45818.1 - 8.8e-14 51.7 6.2 0.00027 21.6 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA45818.1 - 2.2e-09 37.5 1.2 0.013 15.8 0.0 4.7 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPA45818.1 - 8e-07 29.1 0.4 0.011 15.6 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PKD PF00801.20 KPA45818.1 - 0.051 13.4 0.2 22 5.0 0.0 3.6 3 1 1 4 4 4 0 PKD domain RNA_pol_Rpb1_1 PF04997.12 KPA45819.1 - 8.6e-108 360.4 0.0 1.3e-107 359.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KPA45819.1 - 1.5e-101 339.4 0.0 2.3e-101 338.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KPA45819.1 - 6e-76 254.3 0.0 1.2e-75 253.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KPA45819.1 - 1.3e-58 198.0 0.2 2e-58 197.4 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KPA45819.1 - 6.6e-47 158.9 4.2 1.8e-46 157.5 3.9 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KPA45819.1 - 5e-44 150.0 0.0 1e-43 149.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KPA45819.1 - 1.1e-36 125.1 0.2 2.3e-36 124.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KPA45819.1 - 2.9e-06 27.3 194.5 0.0057 17.0 0.0 13.5 10 3 2 13 13 13 8 RNA polymerase Rpb1 C-terminal repeat DIRP PF06584.13 KPA45819.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 DIRP MafB PF06255.13 KPA45819.1 - 0.16 11.4 2.3 0.29 10.5 2.3 1.3 1 0 0 1 1 1 0 Neisseria toxin MafB Glyco_transf_54 PF04666.13 KPA45820.1 - 3e-17 62.4 0.0 4.5e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glycos_transf_2 PF00535.26 KPA45820.1 - 0.084 12.7 0.2 1.9 8.3 0.2 2.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 Peptidase_S9 PF00326.21 KPA45821.1 - 3.9e-29 101.6 0.0 6.8e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KPA45821.1 - 1.5e-24 85.4 6.9 8.5e-07 28.8 1.8 5.6 5 0 0 5 5 5 4 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KPA45821.1 - 2.8e-08 32.9 0.0 0.00021 20.2 0.0 3.2 2 2 0 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DLH PF01738.18 KPA45821.1 - 5e-06 26.2 0.0 0.00026 20.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KPA45821.1 - 0.00035 20.4 0.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KPA45821.1 - 0.00042 20.2 0.0 0.00073 19.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA45821.1 - 0.00069 20.3 0.2 0.0046 17.6 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KPA45821.1 - 0.0014 18.7 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 KPA45821.1 - 0.013 14.7 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ANAPC4_WD40 PF12894.7 KPA45821.1 - 0.03 14.6 0.0 5.9 7.3 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KPA45821.1 - 0.035 13.9 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain GST_C PF00043.25 KPA45822.1 - 8.2e-14 51.6 0.1 1.9e-13 50.5 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPA45822.1 - 4.1e-10 39.5 0.1 1.7e-07 31.1 0.0 2.4 2 1 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA45822.1 - 3e-09 37.0 0.2 3.5e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KPA45822.1 - 2.7e-08 34.0 0.0 6.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPA45822.1 - 1.4e-07 31.8 0.1 4.5e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPA45822.1 - 3.5e-07 30.4 0.0 6.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KPA45822.1 - 1e-05 25.2 0.1 5.2e-05 23.0 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Aldedh PF00171.22 KPA45823.1 - 3.6e-47 160.9 0.3 4e-47 160.8 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 KPA45824.1 - 2.3e-100 336.3 0.0 2.7e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_16 PF10294.9 KPA45826.1 - 5e-18 65.4 0.0 7.2e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KPA45826.1 - 0.00029 21.5 0.0 0.00056 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA45826.1 - 0.0012 19.5 0.0 0.0022 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA45826.1 - 0.0047 16.5 0.0 0.01 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KPA45826.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KPA45826.1 - 0.042 13.6 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 KPA45826.1 - 0.076 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KPA45826.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Mpv17_PMP22 PF04117.12 KPA45827.1 - 0.0036 17.5 0.0 0.0081 16.4 0.0 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Serinc PF03348.15 KPA45827.1 - 0.18 10.7 1.8 0.26 10.2 1.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) EcKinase PF02958.20 KPA45828.1 - 3.6e-15 56.1 0.0 6.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 KPA45828.1 - 1.2e-08 35.1 0.1 6.4e-08 32.8 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPA45828.1 - 0.007 16.0 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RhlB PF12300.8 KPA45829.1 - 0.081 13.1 2.1 0.12 12.5 2.1 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Serglycin PF04360.12 KPA45829.1 - 0.42 10.6 4.3 0.63 10.0 4.3 1.3 1 0 0 1 1 1 0 Serglycin Atrophin-1 PF03154.15 KPA45829.1 - 2.8 6.1 12.9 3.7 5.7 12.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family Sugar_tr PF00083.24 KPA45830.1 - 1.5e-108 363.5 17.1 1.9e-108 363.2 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA45830.1 - 2.3e-22 79.4 31.6 1.7e-17 63.4 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA45830.1 - 0.00063 18.4 17.2 0.0064 15.1 2.6 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein DUF4419 PF14388.6 KPA45833.1 - 2.1e-95 319.7 0.5 2.4e-95 319.4 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) SMI1_KNR4 PF09346.10 KPA45833.1 - 0.0092 16.4 0.2 0.024 15.0 0.2 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Mannitol_dh_C PF08125.13 KPA45834.1 - 2.8e-40 138.4 0.1 4.2e-40 137.8 0.1 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KPA45834.1 - 5.8e-19 68.7 0.3 1.6e-18 67.3 0.1 1.9 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 KPA45834.1 - 0.0037 16.9 0.6 0.0075 15.9 0.2 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3842 PF12953.7 KPA45834.1 - 0.078 13.4 0.3 0.15 12.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) PGI PF00342.19 KPA45835.1 - 3.4e-230 764.7 0.7 3.8e-230 764.5 0.7 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Coatomer_WDAD PF04053.14 KPA45836.1 - 4.3e-174 579.7 0.0 9.9e-174 578.6 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KPA45836.1 - 5.4e-39 131.5 10.6 3.2e-06 27.8 0.0 9.1 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA45836.1 - 9.2e-09 35.5 0.0 3 8.2 0.0 6.2 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA45836.1 - 5.4e-05 22.0 2.2 0.04 12.6 0.0 3.8 2 2 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KPA45836.1 - 0.01 15.8 0.1 7.8 6.6 0.0 3.8 3 2 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.25 KPA45837.1 - 2e-69 233.9 0.0 2.6e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA45837.1 - 2.2e-32 112.4 0.0 3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KPA45837.1 - 4.9e-13 49.5 2.3 4.9e-13 49.5 2.3 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KPA45837.1 - 8e-06 25.0 0.1 1.2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 KPA45837.1 - 0.0012 19.1 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KPA45837.1 - 0.0017 17.7 0.0 0.0041 16.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KPA45837.1 - 0.074 12.7 0.1 0.9 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KPA45837.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Polysacc_deac_1 PF01522.21 KPA45839.1 - 2.1e-29 101.9 0.0 3.2e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KPA45839.1 - 3.6e-11 43.3 31.8 1e-05 25.9 14.8 2.4 2 0 0 2 2 2 2 Chitin recognition protein LLC1 PF14945.6 KPA45839.1 - 0.081 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein MFS_1 PF07690.16 KPA45840.1 - 9.9e-15 54.3 43.0 4e-09 35.9 13.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA45840.1 - 3.9e-06 25.6 18.2 6.5e-06 24.8 18.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4203 PF13886.6 KPA45840.1 - 0.00073 19.3 5.3 0.00073 19.3 5.3 3.9 2 2 3 5 5 5 2 Domain of unknown function (DUF4203) ERM PF00769.19 KPA45841.1 - 0.00081 19.3 16.1 0.00081 19.3 16.1 2.0 2 0 0 2 2 2 1 Ezrin/radixin/moesin family TMPIT PF07851.13 KPA45841.1 - 0.13 11.5 12.6 0.22 10.8 12.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Laminin_II PF06009.12 KPA45841.1 - 0.16 12.0 5.8 0.33 11.0 5.8 1.4 1 0 0 1 1 1 0 Laminin Domain II EzrA PF06160.12 KPA45841.1 - 0.23 9.6 13.4 0.32 9.1 13.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ApoO PF09769.9 KPA45841.1 - 0.32 11.0 3.1 0.75 9.8 3.1 1.6 1 0 0 1 1 1 0 Apolipoprotein O Borrelia_P83 PF05262.11 KPA45841.1 - 1.3 7.4 20.5 2 6.8 20.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.19 KPA45841.1 - 1.4 6.7 11.5 2.1 6.1 11.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KPA45841.1 - 1.6 7.5 22.7 3.2 6.6 22.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 KPA45841.1 - 1.9 8.5 7.9 3.7 7.6 7.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3552 PF12072.8 KPA45841.1 - 2.6 7.4 21.1 4.7 6.6 21.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Prefoldin PF02996.17 KPA45841.1 - 3.7 7.5 14.8 1.2 9.0 9.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit FapA PF03961.13 KPA45841.1 - 4.5 5.8 12.1 7 5.1 12.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A HOOK PF05622.12 KPA45841.1 - 5.9 4.9 24.9 8.8 4.3 24.9 1.2 1 0 0 1 1 1 0 HOOK protein Seryl_tRNA_N PF02403.22 KPA45841.1 - 8.5 6.7 15.7 19 5.5 15.7 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Glyco_hydro_12 PF01670.16 KPA45842.1 - 2.3e-40 138.9 8.7 2.8e-40 138.6 8.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 XhlA PF10779.9 KPA45842.1 - 3.2 8.0 4.3 0.42 10.9 0.3 1.6 2 0 0 2 2 2 0 Haemolysin XhlA Tmemb_cc2 PF10267.9 KPA45843.1 - 0.03 13.5 0.1 0.042 13.0 0.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TAFII28 PF04719.14 KPA45844.1 - 4.7e-33 113.1 0.0 8.5e-33 112.3 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF5008 PF16400.5 KPA45844.1 - 0.11 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5008) Nucleo_P87 PF07267.11 KPA45844.1 - 0.48 9.2 4.0 0.76 8.6 4.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GTP_cyclohydroI PF01227.22 KPA45845.1 - 3.3e-74 248.2 0.3 4.6e-74 247.7 0.3 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KPA45845.1 - 0.0011 19.0 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein MFMR_assoc PF16596.5 KPA45845.1 - 0.15 12.5 5.9 0.28 11.6 5.9 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR MRC1 PF09444.10 KPA45845.1 - 4.6 7.8 11.2 0.15 12.6 5.0 1.6 2 0 0 2 2 2 0 MRC1-like domain PLU-1 PF08429.11 KPA45846.1 - 7.6e-116 387.0 16.2 4.2e-111 371.4 14.4 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KPA45846.1 - 9.1e-43 145.3 0.1 2.4e-42 143.9 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KPA45846.1 - 1.2e-21 77.2 0.0 3.7e-21 75.6 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KPA45846.1 - 1.6e-14 53.5 34.0 3.6e-09 36.4 6.1 3.2 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 KPA45846.1 - 2.1e-14 53.2 0.5 4.7e-14 52.1 0.5 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 KPA45846.1 - 2.8e-11 43.6 7.0 9e-11 42.0 7.0 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger KIX PF02172.16 KPA45846.1 - 0.0052 17.0 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 KIX domain zf-PHD-like PF15446.6 KPA45846.1 - 0.041 13.5 6.5 1.2 8.7 0.4 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 KPA45846.1 - 3.2 7.9 20.2 2.5 8.3 6.5 3.0 2 0 0 2 2 2 0 PHD-finger GIY-YIG PF01541.24 KPA45847.1 - 2.9e-10 40.3 0.0 5.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.6 KPA45847.1 - 0.16 12.2 2.8 0.27 11.5 2.8 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF3449 PF11931.8 KPA45848.1 - 7.8e-78 260.5 3.0 8.3e-78 260.4 0.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KPA45848.1 - 1.5e-26 92.7 0.2 4.1e-26 91.3 0.2 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KPA45848.1 - 3.7e-13 49.1 0.3 8.2e-13 48.0 0.3 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KPA45848.1 - 6.4e-09 35.9 1.9 5.4e-07 29.8 0.8 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KPA45848.1 - 1.5e-07 31.6 1.4 1.5e-07 31.6 1.4 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KPA45848.1 - 0.014 16.2 1.2 2.6 9.1 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KPA45848.1 - 0.023 15.1 0.5 0.023 15.1 0.5 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C4H2 PF10146.9 KPA45848.1 - 0.05 13.9 0.4 0.05 13.9 0.4 2.2 2 1 0 2 2 2 0 Zinc finger-containing protein zf-LYAR PF08790.11 KPA45848.1 - 0.13 12.2 0.5 0.34 10.9 0.5 1.8 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger PRP9_N PF16958.5 KPA45848.1 - 0.14 12.1 18.3 0.11 12.5 1.3 3.1 2 2 1 3 3 3 0 Pre-mRNA-splicing factor PRP9 N-terminus zf-U1 PF06220.12 KPA45848.1 - 0.16 11.8 1.2 0.56 10.0 0.7 2.1 2 0 0 2 2 2 0 U1 zinc finger Neur_chan_memb PF02932.16 KPA45848.1 - 0.89 9.6 2.2 0.73 9.8 0.7 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-C2H2 PF00096.26 KPA45848.1 - 1 9.9 4.4 3.5 8.3 0.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.29 KPA45849.1 - 5.1e-42 143.6 0.2 8.5e-42 142.9 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA45849.1 - 2.7e-33 114.6 0.0 9.7e-33 112.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KPA45849.1 - 0.00051 19.8 0.1 0.00076 19.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KPA45849.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KPA45849.1 - 0.0014 19.0 0.1 0.011 16.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 KPA45849.1 - 0.057 13.4 0.3 0.18 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain DUF5393 PF17371.2 KPA45849.1 - 0.062 11.4 0.1 0.096 10.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) TniB PF05621.11 KPA45849.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KPA45849.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KPA45849.1 - 0.13 12.5 0.8 0.65 10.3 0.8 2.0 1 1 0 1 1 1 0 AAA domain AA_permease_2 PF13520.6 KPA45850.1 - 3.9e-51 174.2 44.8 5.3e-51 173.8 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA45850.1 - 3.1e-20 72.2 42.2 5.6e-20 71.4 42.2 1.3 1 1 0 1 1 1 1 Amino acid permease DUF1688 PF07958.11 KPA45851.1 - 1.3e-178 594.0 0.0 1.5e-178 593.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) An_peroxidase PF03098.15 KPA45851.1 - 0.21 10.1 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Animal haem peroxidase TOM13 PF08219.11 KPA45852.1 - 1.1e-34 118.2 0.0 3.4e-34 116.7 0.0 1.8 2 0 0 2 2 2 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 KPA45852.1 - 1.2e-13 51.3 0.9 1.9e-13 50.7 0.9 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein WXG100 PF06013.12 KPA45852.1 - 0.39 11.0 2.7 0.4 10.9 0.3 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG SEP PF08059.13 KPA45853.1 - 2.3e-23 82.6 0.0 4.8e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 KPA45853.1 - 1.5e-10 40.7 0.3 2.5e-10 40.0 0.3 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KPA45853.1 - 3e-09 37.0 0.0 5.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 UBX domain DUF3246 PF11596.8 KPA45853.1 - 4.1 6.8 8.6 0.58 9.5 3.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Gtr1_RagA PF04670.12 KPA45854.1 - 5.6e-94 313.8 0.0 7.2e-94 313.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KPA45854.1 - 4.6e-08 33.3 0.0 9.1e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA45854.1 - 1.4e-07 31.1 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KPA45854.1 - 2e-07 31.1 0.0 3.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KPA45854.1 - 2.6e-07 30.4 0.0 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KPA45854.1 - 0.00091 18.5 2.3 0.6 9.2 0.3 2.8 2 1 1 3 3 3 2 G-protein alpha subunit ABC_tran PF00005.27 KPA45854.1 - 0.0043 17.6 0.1 0.017 15.6 0.1 1.9 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KPA45854.1 - 0.0047 16.8 0.2 0.23 11.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KPA45854.1 - 0.0057 16.4 1.3 0.064 13.0 0.5 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRPRB PF09439.10 KPA45854.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 KPA45854.1 - 0.022 13.9 0.2 0.05 12.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KPA45854.1 - 0.043 13.3 0.1 0.47 9.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Pkinase PF00069.25 KPA45855.1 - 7.6e-21 74.7 0.0 1.3e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA45855.1 - 6.1e-11 42.1 0.0 1.6e-10 40.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase VWA PF00092.28 KPA45855.1 - 0.0011 19.3 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Pox_ser-thr_kin PF05445.11 KPA45855.1 - 0.011 14.7 0.0 0.092 11.7 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Syntaxin_2 PF14523.6 KPA45856.1 - 0.057 13.8 0.1 7 7.1 0.1 2.8 2 0 0 2 2 2 0 Syntaxin-like protein FBD PF08387.10 KPA45856.1 - 0.069 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 FBD Sporozoite_P67 PF05642.11 KPA45856.1 - 0.14 10.2 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SKG6 PF08693.10 KPA45857.1 - 0.0031 16.9 0.5 0.0058 16.0 0.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 KPA45857.1 - 0.0048 15.8 0.0 0.0076 15.1 0.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4185 PF13810.6 KPA45857.1 - 0.023 13.9 0.3 0.034 13.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) Gly_rich PF12810.7 KPA45857.1 - 0.056 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Glycine rich protein TMEM51 PF15345.6 KPA45857.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1970 PF09301.10 KPA45857.1 - 0.07 13.4 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) CoatB PF10389.9 KPA45857.1 - 0.31 10.9 1.6 0.6 10.0 1.6 1.4 1 0 0 1 1 1 0 Bacteriophage coat protein B adh_short PF00106.25 KPA45858.1 - 5.4e-16 58.6 0.0 2.8e-15 56.3 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA45858.1 - 1.9e-06 27.6 0.0 9.4e-06 25.3 0.0 2.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA45858.1 - 0.00069 19.6 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA45858.1 - 0.0049 16.4 0.0 0.0097 15.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PFK PF00365.20 KPA45858.1 - 0.15 11.4 0.3 0.44 9.8 0.0 1.8 2 0 0 2 2 2 0 Phosphofructokinase DUF2235 PF09994.9 KPA45859.1 - 1.9e-102 342.5 0.4 2.8e-102 342.0 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) ECH_1 PF00378.20 KPA45860.1 - 5.3e-55 186.5 0.0 7e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPA45860.1 - 1.8e-25 90.1 0.0 5.2e-25 88.6 0.0 1.6 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase PWI PF01480.17 KPA45861.1 - 1.4e-14 54.1 0.2 3.6e-14 52.8 0.2 1.7 1 0 0 1 1 1 1 PWI domain Ribosomal_S21 PF01165.20 KPA45862.1 - 1.5e-09 37.4 4.1 2.6e-09 36.7 4.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 HAUS6_N PF14661.6 KPA45863.1 - 2.8e-59 200.5 0.3 6e-59 199.4 0.3 1.6 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus JAKMIP_CC3 PF16034.5 KPA45864.1 - 0.0023 17.9 15.8 0.021 14.8 2.9 2.9 1 1 1 3 3 3 2 JAKMIP CC3 domain RIIa PF02197.17 KPA45864.1 - 0.0082 15.8 0.1 0.024 14.3 0.1 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit TPR_MLP1_2 PF07926.12 KPA45864.1 - 0.018 15.1 0.1 0.018 15.1 0.1 4.3 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein THOC7 PF05615.13 KPA45864.1 - 0.11 12.7 0.4 0.11 12.7 0.4 4.0 3 2 0 3 3 3 0 Tho complex subunit 7 HALZ PF02183.18 KPA45864.1 - 0.74 10.1 15.7 0.57 10.5 0.9 3.9 3 1 1 4 4 4 0 Homeobox associated leucine zipper TRAF_BIRC3_bd PF16673.5 KPA45864.1 - 0.89 9.4 8.4 0.6 9.9 0.3 3.5 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain GIT_CC PF16559.5 KPA45864.1 - 8.3 6.4 13.4 7.9 6.4 0.1 4.5 4 1 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Herpes_BLRF2 PF05812.12 KPA45865.1 - 0.00039 20.6 0.5 0.00074 19.6 0.5 1.5 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein TPR_MLP1_2 PF07926.12 KPA45865.1 - 0.013 15.6 10.4 0.024 14.7 10.4 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein LCD1 PF09798.9 KPA45865.1 - 0.02 13.4 6.7 0.027 13.0 6.7 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF2381 PF09544.10 KPA45865.1 - 0.024 14.2 0.4 0.034 13.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) HALZ PF02183.18 KPA45865.1 - 0.029 14.6 4.0 0.067 13.4 2.7 2.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 KPA45865.1 - 0.035 13.9 1.9 0.035 13.9 1.9 2.3 1 1 1 2 2 2 0 Septum formation initiator Fungal_TACC PF12709.7 KPA45865.1 - 0.053 14.0 3.2 0.14 12.6 2.9 1.8 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins YabA PF06156.13 KPA45865.1 - 0.059 14.0 2.8 0.12 13.1 2.8 1.6 1 0 0 1 1 1 0 Initiation control protein YabA PRKG1_interact PF15898.5 KPA45865.1 - 0.059 14.3 10.4 0.065 14.1 9.2 1.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain bZIP_1 PF00170.21 KPA45865.1 - 0.14 12.3 5.9 0.38 10.9 5.9 1.8 1 1 0 1 1 1 0 bZIP transcription factor CENP-F_N PF10481.9 KPA45865.1 - 0.15 11.6 11.1 0.097 12.3 8.8 1.6 1 1 1 2 2 2 0 Cenp-F N-terminal domain UPF0242 PF06785.11 KPA45865.1 - 0.29 11.2 7.7 0.38 10.8 7.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Chibby PF14645.6 KPA45865.1 - 0.56 10.6 4.7 1.5 9.3 2.7 2.3 1 1 1 2 2 2 0 Chibby family bZIP_2 PF07716.15 KPA45865.1 - 0.57 10.3 8.8 0.07 13.2 3.3 1.8 1 1 2 3 3 3 0 Basic region leucine zipper DUF1003 PF06210.11 KPA45865.1 - 0.6 10.2 4.7 1.2 9.2 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) bZIP_1 PF00170.21 KPA45866.1 - 0.028 14.5 1.6 0.028 14.5 1.6 2.0 2 0 0 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 KPA45866.1 - 0.13 12.6 1.7 0.24 11.8 0.5 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 KPA45867.1 - 0.33 11.0 22.6 0.1 12.6 17.3 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KPA45867.1 - 1.9 7.7 20.7 0.072 12.4 10.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) bZIP_2 PF07716.15 KPA45867.1 - 1.9 8.6 15.1 3.4 7.8 0.5 3.7 2 1 0 3 3 3 0 Basic region leucine zipper Rootletin PF15035.6 KPA45867.1 - 2.7 8.0 25.3 3.3 7.7 11.5 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1811 PF08838.10 KPA45867.1 - 2.9 8.2 4.8 2.7 8.3 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) DUF4472 PF14739.6 KPA45867.1 - 3 8.6 21.4 1.9 9.2 10.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) ADIP PF11559.8 KPA45867.1 - 6.3 6.9 22.8 1.3 9.1 15.0 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KPA45867.1 - 6.4 7.3 27.1 2.7 8.5 9.4 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region Fib_alpha PF08702.10 KPA45868.1 - 0.053 13.7 15.9 0.028 14.6 10.9 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Macoilin PF09726.9 KPA45868.1 - 0.56 8.7 12.6 0.87 8.1 12.6 1.2 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 KPA45868.1 - 1.2 6.9 3.9 2 6.3 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF16 PF01519.16 KPA45868.1 - 7.4 7.1 12.7 2.1 8.9 7.5 2.7 3 1 0 3 3 3 0 Protein of unknown function DUF16 FMN_dh PF01070.18 KPA45869.1 - 5.1e-83 279.0 0.5 5.4e-50 170.4 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 KPA45869.1 - 2.2e-05 23.7 0.2 0.00029 20.0 0.2 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KPA45869.1 - 0.00077 18.8 0.0 0.23 10.7 0.0 2.6 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KPA45869.1 - 0.019 14.2 0.1 1.6 7.9 0.0 2.5 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase Peptidase_M19 PF01244.21 KPA45869.1 - 0.032 13.4 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) TMP-TENI PF02581.17 KPA45869.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase His_biosynth PF00977.21 KPA45869.1 - 0.074 12.5 0.1 9.8 5.6 0.0 2.4 2 1 0 2 2 2 0 Histidine biosynthesis protein Glu_synthase PF01645.17 KPA45869.1 - 0.078 12.1 0.1 0.15 11.2 0.0 1.4 1 1 0 1 1 1 0 Conserved region in glutamate synthase IGPS PF00218.21 KPA45869.1 - 0.15 11.2 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase G3P_antiterm PF04309.12 KPA45869.1 - 0.17 11.3 0.0 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Sugar_tr PF00083.24 KPA45870.1 - 1.3e-30 106.7 27.0 1.3e-28 100.1 27.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA45870.1 - 1.1e-29 103.5 50.1 8.6e-29 100.6 29.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Mei5_like PF17021.5 KPA45870.1 - 0.19 11.8 0.3 0.4 10.7 0.3 1.5 1 0 0 1 1 1 0 Putative double-strand recombination repair-like COX8 PF02285.15 KPA45870.1 - 0.41 10.6 4.4 11 6.0 0.3 3.3 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIII TIP120 PF08623.10 KPA45871.1 - 3.4e-73 244.9 4.6 4.9e-69 231.4 0.1 5.3 3 2 3 6 6 6 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KPA45871.1 - 3.8e-13 49.6 18.2 0.012 16.0 1.3 9.1 7 2 2 9 9 8 4 HEAT repeats HEAT PF02985.22 KPA45871.1 - 7.1e-12 44.5 16.6 0.82 10.1 0.1 10.9 11 0 0 11 11 10 3 HEAT repeat Adaptin_N PF01602.20 KPA45871.1 - 1.2e-10 40.6 14.3 0.015 13.9 0.0 6.7 5 2 2 7 7 7 4 Adaptin N terminal region RTP1_C1 PF10363.9 KPA45871.1 - 2.6e-07 30.8 6.4 0.4 10.9 0.0 6.6 7 0 0 7 7 7 2 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 KPA45871.1 - 2.7e-05 24.7 1.7 1.4 9.6 0.0 7.4 8 1 1 9 9 9 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KPA45871.1 - 3.1e-05 23.7 1.2 5.9 6.4 0.0 5.9 6 2 1 7 7 7 1 CLASP N terminal Cnd1 PF12717.7 KPA45871.1 - 5.7e-05 23.2 19.7 0.15 12.1 0.6 6.9 7 1 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KPA45871.1 - 0.00012 21.4 1.8 1.4 8.0 0.2 5.1 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain VHS PF00790.19 KPA45871.1 - 0.029 14.2 0.5 2.7 7.8 0.0 4.0 4 1 0 5 5 5 0 VHS domain RIX1 PF08167.12 KPA45871.1 - 0.035 13.9 9.6 4.2 7.1 0.1 5.5 4 2 1 5 5 5 0 rRNA processing/ribosome biogenesis PUL PF08324.11 KPA45871.1 - 0.041 13.1 1.8 0.26 10.5 1.8 2.5 1 1 0 1 1 1 0 PUL domain RasGEF_N_2 PF14663.6 KPA45871.1 - 0.089 13.2 2.8 9.6 6.7 0.0 5.0 6 0 0 6 6 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3437 PF11919.8 KPA45871.1 - 0.098 12.6 0.0 47 4.0 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) DUF3510 PF12022.8 KPA45871.1 - 0.11 12.9 0.3 0.48 10.8 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) HEAT_EZ PF13513.6 KPA45871.1 - 0.12 12.9 21.2 25 5.5 0.1 10.5 10 3 3 13 13 12 0 HEAT-like repeat MMS19_C PF12460.8 KPA45871.1 - 0.87 8.6 10.2 3.3 6.7 0.4 4.7 5 1 1 6 6 6 0 RNAPII transcription regulator C-terminal RasGEF_N PF00618.20 KPA45873.1 - 0.12 12.6 0.5 0.27 11.5 0.1 1.8 2 0 0 2 2 2 0 RasGEF N-terminal motif Apc13p PF05839.11 KPA45874.1 - 2.1e-35 120.8 0.1 2.4e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.16 KPA45875.1 - 8e-42 142.4 0.0 9.5e-42 142.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component BCS1_N PF08740.11 KPA45876.1 - 4.3e-31 108.4 2.2 4.3e-31 108.4 2.2 2.2 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KPA45876.1 - 1.2e-16 61.4 0.0 8e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPA45876.1 - 0.0018 18.1 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain CDC45 PF02724.14 KPA45876.1 - 0.0018 16.7 11.2 0.0018 16.7 11.2 1.6 2 0 0 2 2 2 1 CDC45-like protein FXR_C1 PF16096.5 KPA45876.1 - 0.0093 16.2 8.5 0.029 14.6 8.5 1.9 1 0 0 1 1 1 1 Fragile X-related 1 protein C-terminal region 2 AAA_11 PF13086.6 KPA45876.1 - 0.016 15.0 7.1 0.41 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KPA45876.1 - 0.097 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 KPA45876.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KPA45876.1 - 0.2 11.8 4.2 0.22 11.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain RR_TM4-6 PF06459.12 KPA45876.1 - 0.44 10.3 7.2 1 9.1 7.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF3_subunit PF08597.10 KPA45876.1 - 0.49 10.3 20.8 0.075 12.9 11.4 3.0 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit TraG-D_C PF12696.7 KPA45876.1 - 0.52 10.3 3.6 1.1 9.2 3.6 1.6 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Zip PF02535.22 KPA45876.1 - 0.63 9.2 2.1 1.1 8.4 2.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter VIR_N PF15912.5 KPA45876.1 - 2.6 7.6 10.2 5.1 6.6 10.2 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal CRAL_TRIO PF00650.20 KPA45877.1 - 4e-39 133.9 0.0 5.3e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KPA45877.1 - 5.8e-14 52.0 0.5 5.8e-14 52.0 0.5 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KPA45877.1 - 0.095 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Exo_endo_phos PF03372.23 KPA45878.1 - 7.2e-10 38.8 0.0 2.4e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4748 PF15932.5 KPA45879.1 - 1.4e-26 92.0 0.5 2.1e-26 91.4 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) DUF4439 PF14530.6 KPA45879.1 - 0.0027 18.4 0.7 0.0033 18.1 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) Rav1p_C PF12234.8 KPA45879.1 - 0.14 10.5 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal CTD_bind PF04818.13 KPA45880.1 - 3.3e-13 50.2 0.2 9.3e-13 48.8 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RSRP PF17069.5 KPA45880.1 - 0.035 13.7 62.0 0.076 12.6 62.0 1.6 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 B56 PF01603.20 KPA45881.1 - 7.2e-192 637.9 4.3 8.4e-192 637.7 4.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KPA45881.1 - 5.5e-05 23.1 1.3 0.31 10.9 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Ndc1_Nup PF09531.10 KPA45881.1 - 0.5 9.0 5.9 0.69 8.5 5.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF737 PF05300.11 KPA45881.1 - 0.62 10.4 6.2 0.53 10.6 3.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Tau95 PF09734.9 KPA45882.1 - 1e-39 136.6 1.4 1.3e-39 136.2 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KPA45882.1 - 2.9e-33 114.8 0.0 5.3e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain zf-C2H2_4 PF13894.6 KPA45883.1 - 3.6e-09 36.7 8.4 0.12 13.2 0.1 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KPA45883.1 - 8.5e-09 35.2 9.6 0.0003 20.7 0.2 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KPA45883.1 - 1.8e-05 24.9 9.8 0.54 10.8 0.2 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KPA45883.1 - 0.00014 22.1 8.1 0.15 12.4 0.4 4.1 2 2 2 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 KPA45883.1 - 0.00023 21.4 0.8 0.00023 21.4 0.8 2.2 2 1 1 3 3 3 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 KPA45883.1 - 0.00063 20.0 17.9 0.024 15.1 0.1 4.8 4 1 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 KPA45883.1 - 0.0007 19.8 9.0 0.16 12.3 1.6 3.2 2 2 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KPA45883.1 - 0.0055 17.0 5.3 0.29 11.5 0.0 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 KPA45883.1 - 0.01 15.7 0.9 4.3 7.3 0.2 3.0 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 KPA45883.1 - 0.12 13.2 5.4 0.35 11.7 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon family Zn_ribbon_SprT PF17283.2 KPA45883.1 - 0.12 12.3 2.0 0.72 9.8 0.1 2.8 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Elf1 PF05129.13 KPA45883.1 - 0.35 10.9 9.4 0.66 10.1 0.1 3.6 2 2 1 3 3 3 0 Transcription elongation factor Elf1 like TF_Zn_Ribbon PF08271.12 KPA45883.1 - 0.7 9.5 4.7 12 5.5 0.8 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_3rep PF18868.1 KPA45883.1 - 1.7 9.3 5.7 70 4.1 0.7 3.6 2 2 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_ZIC PF18366.1 KPA45883.1 - 4.3 7.5 6.6 41 4.4 0.1 4.2 4 1 1 5 5 5 0 Zic proteins zinc finger domain Zn-ribbon_8 PF09723.10 KPA45883.1 - 4.7 7.4 11.3 0.95 9.6 1.3 3.0 3 0 0 3 3 3 0 Zinc ribbon domain DHHC PF01529.20 KPA45884.1 - 3.9e-36 124.1 11.0 3.9e-36 124.1 11.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase HD PF01966.22 KPA45885.1 - 7.2e-07 29.5 0.3 1.2e-06 28.8 0.3 1.3 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KPA45885.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme PI-PLC-X PF00388.19 KPA45886.1 - 3.8e-58 195.2 0.0 8.7e-58 194.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KPA45886.1 - 3.3e-44 149.9 0.1 1e-43 148.3 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KPA45886.1 - 1.6e-06 28.3 0.0 5.5e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 KPA45886.1 - 0.001 19.5 0.0 0.0026 18.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like Zw10 PF06248.13 KPA45887.1 - 2.5e-09 36.3 3.1 0.00019 20.1 4.6 2.6 3 0 0 3 3 3 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KPA45887.1 - 0.013 15.2 0.1 0.19 11.5 0.0 2.6 3 0 0 3 3 3 0 Retrograde transport protein Dsl1 C terminal CagS PF16707.5 KPA45887.1 - 0.15 12.1 0.2 0.38 10.8 0.2 1.6 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori HWE_HK PF07536.14 KPA45887.1 - 0.18 12.5 2.2 1.1 10.0 0.1 3.0 3 0 0 3 3 3 0 HWE histidine kinase Peptidase_M16_C PF05193.21 KPA45888.1 - 3.3e-19 69.6 0.0 3.2e-14 53.4 0.0 3.1 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KPA45888.1 - 6.6e-09 35.9 0.0 1.1e-06 28.7 0.0 2.6 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KPA45888.1 - 0.00085 18.5 3.2 0.91 8.6 3.0 2.4 2 0 0 2 2 2 2 Peptidase M16C associated Peptidase_M48_N PF16491.5 KPA45889.1 - 4e-66 222.4 9.9 4e-66 222.4 9.9 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KPA45889.1 - 3.3e-47 160.8 0.0 5.9e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KPA45889.1 - 0.00039 19.7 0.1 0.00087 18.6 0.1 1.6 1 0 0 1 1 1 1 BlaR1 peptidase M56 Taxilin PF09728.9 KPA45890.1 - 6.6e-92 308.0 61.9 9.4e-92 307.5 61.9 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF4810 PF16068.5 KPA45890.1 - 0.00048 20.6 0.7 0.00048 20.6 0.7 4.3 2 2 3 5 5 5 1 Domain of unknown function (DUF4810) Laminin_I PF06008.14 KPA45890.1 - 1.3 8.7 42.0 1.7 8.3 14.9 3.3 2 1 1 3 3 3 0 Laminin Domain I TMF_TATA_bd PF12325.8 KPA45890.1 - 6 7.1 58.2 0.43 10.8 15.9 5.0 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding M16C_assoc PF08367.11 KPA45891.1 - 5e-83 278.1 0.0 9e-83 277.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KPA45891.1 - 1e-32 113.6 0.0 1.1e-22 80.9 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KPA45891.1 - 7.6e-09 35.7 0.0 7.3e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) UvrA_inter PF17760.1 KPA45891.1 - 0.12 12.5 0.2 0.56 10.3 0.1 2.1 2 0 0 2 2 2 0 UvrA interaction domain Orn_Arg_deC_N PF02784.16 KPA45892.1 - 4.3e-86 288.3 0.0 5.7e-86 287.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KPA45892.1 - 7.9e-18 64.5 0.0 1.2e-17 64.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SNF2_N PF00176.23 KPA45893.1 - 2.7e-46 157.9 0.1 1.6e-41 142.2 0.0 2.5 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KPA45893.1 - 3e-16 59.7 0.0 1.1e-15 57.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA45893.1 - 2.7e-06 27.5 0.8 5.3e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KPA45893.1 - 2.8e-06 27.1 10.0 2.8e-06 27.1 10.0 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPA45893.1 - 0.0021 17.9 10.3 0.0021 17.9 10.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA45893.1 - 0.0041 17.4 11.9 0.0041 17.4 11.9 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPA45893.1 - 0.0077 16.1 10.1 0.0077 16.1 10.1 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 KPA45893.1 - 0.026 13.7 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 KPA45893.1 - 0.053 12.4 0.0 0.16 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 AT_hook PF02178.19 KPA45893.1 - 0.14 12.1 28.3 0.15 12.0 2.4 4.6 4 0 0 4 4 4 0 AT hook motif zf_UBZ PF18439.1 KPA45893.1 - 0.78 9.4 10.8 0.21 11.2 1.0 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-RING_UBOX PF13445.6 KPA45893.1 - 2.2 8.4 11.0 6 7.0 11.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_10 PF16685.5 KPA45893.1 - 8.4 6.6 15.2 0.14 12.3 6.4 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 LRR_6 PF13516.6 KPA45894.1 - 2.1e-06 27.3 0.1 0.11 12.6 0.0 6.0 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.7 KPA45894.1 - 0.00084 19.7 0.8 6.9 7.2 0.1 5.1 4 3 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPA45894.1 - 0.0013 18.4 0.1 0.021 14.6 0.1 2.9 3 0 0 3 3 3 1 Leucine rich repeat Lipase_3 PF01764.25 KPA45895.1 - 6.4e-31 107.1 0.0 1.1e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.12 KPA45895.1 - 0.00095 18.8 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase Lipase3_N PF03893.16 KPA45895.1 - 0.0016 18.4 0.1 0.0035 17.3 0.1 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 KPA45895.1 - 0.0058 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA45895.1 - 0.036 14.7 0.0 0.045 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L34 PF00468.17 KPA45896.1 - 6.6e-09 35.6 11.2 1e-08 35.0 11.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Treslin_N PF15292.6 KPA45896.1 - 0.06 11.7 0.1 0.061 11.7 0.1 1.1 1 0 0 1 1 1 0 Treslin N-terminus Dynamin_N PF00350.23 KPA45897.1 - 1e-21 77.7 0.0 2.1e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KPA45897.1 - 2.3e-15 56.6 0.0 2.7e-10 39.9 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KPA45897.1 - 9.3e-06 25.7 0.0 6.1e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPA45897.1 - 0.0016 18.0 0.0 0.38 10.3 0.0 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B Roc PF08477.13 KPA45897.1 - 0.061 13.5 0.2 4 7.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase tRNA-synt_1g PF09334.11 KPA45898.1 - 9.4e-97 324.2 1.4 4.8e-96 321.9 1.4 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) Acetyltransf_3 PF13302.7 KPA45898.1 - 8.8e-25 88.0 0.1 4.9e-24 85.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain tRNA-synt_1 PF00133.22 KPA45898.1 - 2.1e-20 72.6 5.2 3.7e-10 38.7 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KPA45898.1 - 9.6e-11 41.6 0.1 2.6e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain FR47 PF08445.10 KPA45898.1 - 0.0002 21.2 0.1 0.003 17.5 0.1 2.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KPA45898.1 - 0.00022 20.9 0.1 0.00088 19.0 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA45898.1 - 0.001 19.3 0.1 0.0045 17.2 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Anticodon_1 PF08264.13 KPA45898.1 - 0.002 18.1 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Acetyltransf_7 PF13508.7 KPA45898.1 - 0.012 16.0 0.0 0.038 14.4 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NTF2 PF02136.20 KPA45899.1 - 0.0079 16.8 0.5 0.028 15.0 0.5 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KPA45899.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 PPTA PF01239.22 KPA45900.1 - 6.1e-35 117.9 17.0 9.2e-08 31.6 0.1 6.0 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_7 PF13176.6 KPA45900.1 - 0.0004 20.2 0.6 0.082 13.0 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF4689 PF15755.5 KPA45900.1 - 0.025 14.2 1.0 0.046 13.3 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) GHMP_kinases_N PF00288.26 KPA45901.1 - 2.9e-16 59.4 0.0 7.8e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KPA45901.1 - 1.8e-09 37.8 0.0 4.7e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KPA45901.1 - 0.003 17.1 0.1 0.0058 16.2 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Glyoxalase PF00903.25 KPA45902.1 - 1.9e-08 34.6 0.0 2.4e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KPA45902.1 - 0.034 14.1 0.1 0.051 13.5 0.1 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain EH_Signature PF15611.6 KPA45903.1 - 0.025 14.0 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 EH_Signature domain ABM PF03992.16 KPA45903.1 - 0.13 12.4 1.1 9.7 6.4 0.5 2.6 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Ribosomal_L38e PF01781.18 KPA45904.1 - 2.3e-30 104.5 4.7 2.7e-30 104.3 4.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Herpes_UL3 PF03369.13 KPA45904.1 - 0.0024 18.4 0.9 0.0025 18.3 0.9 1.1 1 0 0 1 1 1 1 Herpesvirus UL3 protein Cyclophil_like2 PF18050.1 KPA45904.1 - 0.041 13.8 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin-like family DUF5374 PF17344.2 KPA45904.1 - 0.072 13.0 0.8 0.11 12.4 0.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5374) PAZ_siRNAbind PF12212.8 KPA45904.1 - 0.23 11.3 3.0 1.8 8.4 0.2 2.0 1 1 1 2 2 2 0 PAZ domain Ish1 PF10281.9 KPA45905.1 - 4.3e-05 23.7 0.3 7.8e-05 22.9 0.1 1.5 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KPA45905.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 SAP domain DUF4538 PF15061.6 KPA45905.1 - 0.064 13.0 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) NMO PF03060.15 KPA45907.1 - 4.1e-50 171.0 0.1 6.5e-50 170.4 0.1 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KPA45907.1 - 6.5e-11 41.8 0.2 3.7e-10 39.3 0.3 2.0 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KPA45907.1 - 0.00014 21.0 0.5 0.00025 20.2 0.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KPA45907.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase FAD_binding_4 PF01565.23 KPA45908.1 - 7e-17 61.5 0.1 1.1e-16 60.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain F-box-like PF12937.7 KPA45910.1 - 0.00084 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KPA45910.1 - 0.032 14.1 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 F-box IBD PF10416.9 KPA45910.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD F-box PF00646.33 KPA45910.1 - 0.075 12.9 0.2 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 F-box domain PARP PF00644.20 KPA45911.1 - 2e-59 200.5 2.5 2.1e-59 200.4 0.0 2.3 2 1 2 4 4 4 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KPA45911.1 - 5.7e-47 159.2 0.7 9.1e-47 158.6 0.7 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KPA45911.1 - 3e-25 88.1 0.5 7.8e-25 86.7 0.5 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 KPA45911.1 - 1.1e-12 48.1 0.0 2.2e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KPA45911.1 - 5.8e-07 29.8 0.0 1.3e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KPA45911.1 - 1.1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain SMYLE_N PF18615.1 KPA45911.1 - 6.1 6.3 7.8 12 5.3 7.8 1.4 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Zn_clus PF00172.18 KPA45912.1 - 8e-17 61.1 25.2 9.7e-09 35.2 5.9 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA45912.1 - 3.1e-13 49.4 0.0 5.2e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3433 PF11915.8 KPA45913.1 - 6.1e-33 113.2 21.7 7.2e-20 71.3 4.6 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Fungal_trans PF04082.18 KPA45913.1 - 1.1e-10 41.0 0.6 1.9e-10 40.2 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA45913.1 - 3.8e-10 39.7 17.4 1.2e-07 31.8 12.2 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_Pi_cotrans PF02690.15 KPA45913.1 - 0.1 12.7 0.7 0.33 11.1 0.7 1.8 1 0 0 1 1 1 0 Na+/Pi-cotransporter Hap4_Hap_bind PF10297.9 KPA45916.1 - 3.2e-09 36.6 6.9 1.4e-08 34.5 6.9 2.3 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KPA45916.1 - 0.00019 21.5 10.0 0.0004 20.4 9.5 1.8 1 1 0 1 1 1 1 bZIP transcription factor dsrm PF00035.26 KPA45916.1 - 0.12 13.1 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif Glutaredoxin2_C PF04399.13 KPA45916.1 - 0.23 11.3 0.5 0.41 10.5 0.5 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain HMMR_N PF15905.5 KPA45916.1 - 0.32 10.4 7.3 0.55 9.6 7.3 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Fmp27_WPPW PF10359.9 KPA45916.1 - 1.6 7.5 5.4 2.2 7.0 5.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Nup54 PF13874.6 KPA45916.1 - 1.8 8.6 9.4 3.1 7.9 9.4 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 COG2 PF06148.11 KPA45917.1 - 1.4e-24 86.7 0.2 2.5e-24 85.8 0.2 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KPA45917.1 - 0.00065 19.7 0.2 0.0037 17.3 0.1 2.3 1 1 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KPA45917.1 - 0.0027 17.9 0.7 0.0061 16.7 0.2 1.9 2 1 0 2 2 2 1 Golgi transport complex subunit 5 Vps54_N PF10475.9 KPA45917.1 - 0.0067 15.7 0.0 0.023 14.0 0.0 1.7 1 1 1 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Spc7 PF08317.11 KPA45917.1 - 0.011 14.7 0.7 0.018 14.0 0.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein COMP PF11598.8 KPA45917.1 - 0.024 15.1 0.6 0.25 11.8 0.1 2.6 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Dor1 PF04124.12 KPA45917.1 - 0.038 12.7 1.3 0.069 11.8 0.6 1.6 2 0 0 2 2 2 0 Dor1-like family NPV_P10 PF05531.12 KPA45917.1 - 0.051 14.0 0.0 0.72 10.4 0.0 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Sec8_exocyst PF04048.14 KPA45917.1 - 0.061 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DLP_helical PF18709.1 KPA45917.1 - 0.088 12.0 0.2 0.22 10.7 0.1 1.6 2 0 0 2 2 2 0 Dynamin-like helical domain Exonuc_VII_L PF02601.15 KPA45917.1 - 0.09 12.3 0.3 0.15 11.6 0.2 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4611 PF15387.6 KPA45917.1 - 0.099 12.9 3.6 0.25 11.6 3.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) DUF1664 PF07889.12 KPA45917.1 - 0.11 12.5 0.2 0.22 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 KPA45917.1 - 0.83 9.8 3.8 34 4.5 0.7 3.1 2 1 0 3 3 3 0 Nucleoporin complex subunit 54 SurE PF01975.17 KPA45918.1 - 2.7e-29 102.3 0.1 5.5e-29 101.3 0.1 1.5 1 0 0 1 1 1 1 Survival protein SurE Ribosomal_L1 PF00687.21 KPA45918.1 - 1.6e-22 80.2 0.1 2.5e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family PHM7_cyt PF14703.6 KPA45919.1 - 0.0057 16.9 7.0 0.01 16.1 7.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter betaPIX_CC PF16523.5 KPA45919.1 - 0.023 14.5 4.7 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 betaPIX coiled coil Fez1 PF06818.15 KPA45919.1 - 0.048 14.1 10.4 0.023 15.2 7.8 1.9 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 KPA45919.1 - 0.059 13.6 8.6 0.031 14.4 5.7 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_S46 PF10459.9 KPA45919.1 - 0.06 12.0 5.7 0.085 11.5 5.7 1.1 1 0 0 1 1 1 0 Peptidase S46 Syntaxin_2 PF14523.6 KPA45919.1 - 1.2 9.6 11.8 0.3 11.5 4.8 2.8 2 1 1 3 3 3 0 Syntaxin-like protein FapA PF03961.13 KPA45919.1 - 1.5 7.4 4.6 2 6.9 4.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ATG16 PF08614.11 KPA45919.1 - 2.4 8.3 16.9 0.47 10.6 11.7 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) OmpH PF03938.14 KPA45919.1 - 5 7.5 10.1 2 8.8 7.4 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SnAC PF14619.6 KPA45919.1 - 6 7.6 10.3 3 8.5 0.2 3.0 2 1 1 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex COesterase PF00135.28 KPA45920.1 - 2.5e-92 310.4 0.0 2.8e-91 306.9 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA45920.1 - 7.2e-08 32.5 0.0 1.8e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KPA45920.1 - 0.12 11.9 0.1 0.98 8.9 0.0 2.3 2 1 0 2 2 2 0 Esterase PHB depolymerase PAF-AH_p_II PF03403.13 KPA45921.1 - 1.1e-43 149.2 0.0 2.9e-38 131.4 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KPA45921.1 - 2.7e-05 23.2 0.0 0.00011 21.2 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KPA45921.1 - 0.00087 18.6 0.0 0.65 9.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KPA45921.1 - 0.0049 15.9 0.0 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase DLH PF01738.18 KPA45921.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KPA45921.1 - 0.18 12.4 0.3 0.52 10.9 0.3 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Acetyltransf_10 PF13673.7 KPA45922.1 - 1.1e-07 31.8 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA45922.1 - 1.3e-06 28.7 0.0 1.9e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA45922.1 - 9.6e-06 25.8 0.0 1.5e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Connexin43 PF03508.13 KPA45922.1 - 0.053 13.1 0.3 0.093 12.3 0.3 1.3 1 0 0 1 1 1 0 Gap junction alpha-1 protein (Cx43) zf-C2H2 PF00096.26 KPA45923.1 - 2.2e-09 37.3 11.5 0.00012 22.4 1.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPA45923.1 - 6.3e-07 29.6 10.2 3.4e-05 24.1 2.0 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPA45923.1 - 1.6e-05 25.3 10.8 0.018 15.8 1.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KPA45923.1 - 0.0093 16.3 2.2 0.035 14.5 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KPA45923.1 - 0.015 15.3 0.4 0.015 15.3 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA45923.1 - 0.037 14.3 2.9 0.11 12.9 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 KPA45923.1 - 0.19 11.6 5.6 0.21 11.5 0.9 2.3 1 1 1 2 2 2 0 SprT-like zinc ribbon domain ADK_lid PF05191.14 KPA45923.1 - 4.4 7.4 5.2 14 5.8 1.4 3.2 2 1 1 3 3 3 0 Adenylate kinase, active site lid EST1_DNA_bind PF10373.9 KPA45924.1 - 4.1e-10 39.6 0.3 9.6e-10 38.4 0.3 1.8 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Fungal_trans_2 PF11951.8 KPA45925.1 - 2.9e-22 79.0 0.0 5.9e-22 78.0 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Hydrolase_4 PF12146.8 KPA45926.1 - 3.5e-08 33.0 0.1 0.0026 17.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA45926.1 - 0.059 13.0 0.0 6.1 6.4 0.1 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Zn_clus PF00172.18 KPA45928.1 - 9.8e-05 22.4 8.2 0.00015 21.8 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_binding_3 PF13727.6 KPA45928.1 - 0.049 13.6 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 CoA-binding domain Fasciclin PF02469.22 KPA45929.1 - 1.7e-32 112.3 0.0 4.6e-18 65.7 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain DUF924 PF06041.11 KPA45930.1 - 3.2e-40 138.2 0.0 5.1e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) O-antigen_lig PF13425.6 KPA45930.1 - 0.044 12.6 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Dynactin_p62 PF05502.13 KPA45932.1 - 5.8e-203 675.0 5.7 1.2e-202 674.0 5.7 1.5 1 1 0 1 1 1 1 Dynactin p62 family zinc_ribbon_10 PF10058.9 KPA45932.1 - 0.62 9.8 0.0 0.62 9.8 0.0 3.4 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein Ribosomal_S7e PF01251.18 KPA45933.1 - 3.5e-82 274.6 0.3 6e-82 273.9 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S7e PseudoU_synth_1 PF01416.20 KPA45933.1 - 3.8e-09 37.0 0.0 1.3e-07 32.0 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 KPA45933.1 - 0.052 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) CHZ PF09649.10 KPA45934.1 - 0.0054 16.2 2.1 0.012 15.1 2.1 1.5 1 0 0 1 1 1 1 Histone chaperone domain CHZ WD40 PF00400.32 KPA45935.1 - 3.8e-40 135.1 21.9 3.5e-08 34.0 0.1 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KPA45935.1 - 6.4e-14 51.6 0.8 1.2e-13 50.7 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA45935.1 - 4.7e-11 42.3 0.3 1.2e-10 41.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KPA45935.1 - 3.1e-09 37.0 0.8 0.0054 17.0 0.0 5.8 2 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA45935.1 - 1.1e-06 27.6 4.1 0.66 8.5 0.1 4.2 3 1 1 4 4 4 4 Nucleoporin Nup120/160 F-box_4 PF15966.5 KPA45935.1 - 0.00016 21.5 0.1 0.00045 20.1 0.1 1.8 1 0 0 1 1 1 1 F-box WD40_like PF17005.5 KPA45935.1 - 0.084 12.2 0.3 1.5 8.1 0.1 2.5 2 1 1 3 3 3 0 WD40-like domain PALB2_WD40 PF16756.5 KPA45935.1 - 0.31 9.9 3.8 18 4.1 0.1 3.5 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Apolipoprotein PF01442.18 KPA45937.1 - 7.3 6.4 61.3 1.6 8.5 9.8 6.9 6 1 0 6 6 6 0 Apolipoprotein A1/A4/E domain RINGv PF12906.7 KPA45939.1 - 3.5e-17 62.3 6.6 5.9e-17 61.5 6.6 1.4 1 0 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 KPA45939.1 - 0.0084 16.1 1.9 0.017 15.1 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KPA45939.1 - 0.013 15.9 6.9 0.021 15.2 6.9 1.4 1 0 0 1 1 1 0 Ring finger domain NUDE_C PF04880.13 KPA45940.1 - 1.1e-40 140.0 10.8 1.1e-40 140.0 10.8 4.7 2 1 3 5 5 5 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 KPA45940.1 - 0.023 15.1 10.1 0.023 15.1 10.1 4.7 2 1 2 4 4 4 0 Cell division protein ZapB PSII_Pbs27 PF13326.6 KPA45940.1 - 0.051 13.9 2.2 0.13 12.6 2.2 1.6 1 0 0 1 1 1 0 Photosystem II Pbs27 Fez1 PF06818.15 KPA45940.1 - 0.42 11.0 28.3 0.51 10.7 13.0 2.8 2 1 1 3 3 3 0 Fez1 ERM PF00769.19 KPA45940.1 - 0.75 9.6 34.2 1.5 8.6 26.5 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Chibby PF14645.6 KPA45940.1 - 1.5 9.2 10.9 3.2 8.2 2.5 2.6 1 1 1 2 2 2 0 Chibby family Filament PF00038.21 KPA45940.1 - 1.7 8.1 32.5 0.62 9.6 11.0 2.5 2 1 1 3 3 3 0 Intermediate filament protein PRKG1_interact PF15898.5 KPA45940.1 - 3.7 8.5 31.7 0.61 11.0 11.7 3.2 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain ACC_central PF08326.12 KPA45941.1 - 4.2e-283 941.1 0.0 5.3e-283 940.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KPA45941.1 - 3.5e-182 606.5 0.0 4.7e-182 606.0 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KPA45941.1 - 1.5e-52 178.2 0.0 2.9e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KPA45941.1 - 7.2e-28 97.3 0.1 1.5e-27 96.3 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KPA45941.1 - 1.2e-24 86.5 0.0 5.7e-20 71.4 0.0 3.5 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KPA45941.1 - 6.5e-17 61.1 0.0 1.4e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KPA45941.1 - 0.0041 17.2 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KPA45941.1 - 0.0082 16.0 0.1 0.033 14.0 0.0 2.0 2 0 0 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KPA45941.1 - 0.014 14.9 0.0 0.039 13.5 0.0 1.7 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus GxGYxYP_N PF16216.5 KPA45941.1 - 0.016 15.4 0.1 0.089 13.0 0.0 2.3 2 0 0 2 2 2 0 GxGYxY sequence motif in domain of unknown function N-terminal ATP-grasp PF02222.22 KPA45941.1 - 0.093 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 KPA45941.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Utp13 PF08625.11 KPA45941.1 - 0.61 10.0 5.1 0.26 11.2 1.4 2.2 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain SBF PF01758.16 KPA45942.1 - 1.7e-57 194.3 8.2 1.7e-57 194.3 8.2 2.0 3 0 0 3 3 3 1 Sodium Bile acid symporter family DUF1129 PF06570.11 KPA45942.1 - 0.017 14.6 0.3 0.017 14.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) 2TM PF13239.6 KPA45942.1 - 0.96 9.8 0.0 0.96 9.8 0.0 4.1 4 2 0 4 4 4 0 2TM domain bZIP_1 PF00170.21 KPA45943.1 - 0.7 10.0 5.9 1.2 9.3 5.3 1.6 1 1 1 2 2 2 0 bZIP transcription factor Pex14_N PF04695.13 KPA45943.1 - 0.85 10.3 12.9 23 5.6 12.9 2.2 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BolA PF01722.18 KPA45944.1 - 4.3e-10 39.7 0.0 9.9e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein tRNA-synt_1d PF00750.19 KPA45945.1 - 2.3e-99 332.7 1.8 3e-99 332.3 1.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KPA45945.1 - 1.8e-28 99.1 0.2 5.2e-28 97.6 0.2 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KPA45945.1 - 2.9e-08 34.2 0.0 1.2e-07 32.2 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain POT1 PF02765.17 KPA45945.1 - 0.028 14.3 0.0 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 Bestrophin PF01062.21 KPA45946.1 - 8.9e-38 130.4 0.1 1.9e-37 129.3 0.1 1.4 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF3431 PF11913.8 KPA45947.1 - 1.2e-86 290.0 0.1 1.4e-86 289.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Med22 PF06179.12 KPA45948.1 - 4.6e-20 71.8 1.2 6.1e-20 71.4 1.2 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Peptidase_S8 PF00082.22 KPA45949.1 - 3.8e-46 157.7 0.5 5.6e-46 157.1 0.5 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KPA45949.1 - 1.4e-18 67.6 0.2 2.5e-18 66.8 0.2 1.4 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 KPA45949.1 - 0.00048 20.1 0.0 0.0016 18.4 0.0 2.0 1 0 0 1 1 1 1 PA domain NFACT-R_1 PF05670.13 KPA45950.1 - 3.1e-30 105.0 0.1 7.8e-30 103.7 0.1 1.7 1 1 0 1 1 1 1 NFACT protein RNA binding domain Mrx7 PF10906.8 KPA45950.1 - 0.25 11.6 3.8 0.23 11.7 1.8 2.0 1 1 1 2 2 2 0 MIOREX complex component 7 Velvet PF11754.8 KPA45951.1 - 0.00088 19.3 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 Velvet factor MFS_1 PF07690.16 KPA45952.1 - 2.4e-26 92.5 38.9 2.4e-26 92.5 38.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA45952.1 - 1.3e-05 24.3 26.4 2.8e-05 23.2 21.6 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.8 KPA45952.1 - 0.0028 16.4 11.3 0.029 13.0 1.5 2.8 1 1 2 3 3 3 2 Vacuole effluxer Atg22 like HeLo PF14479.6 KPA45953.1 - 6.5e-06 26.1 0.7 0.064 13.1 0.1 2.6 1 1 1 2 2 2 2 Prion-inhibition and propagation Cofilin_ADF PF00241.20 KPA45955.1 - 8.4e-34 116.0 0.0 2.8e-18 65.8 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.27 KPA45956.1 - 3.3e-67 222.5 1.6 9.3e-22 76.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC_tran PF00005.27 KPA45957.1 - 4.5e-45 153.5 0.0 8.3e-28 97.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KPA45957.1 - 8e-22 78.2 9.8 2.4e-13 50.4 5.9 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KPA45957.1 - 1.8e-14 53.8 0.3 0.0011 18.5 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPA45957.1 - 8.8e-08 32.9 0.1 0.0009 19.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KPA45957.1 - 1.4e-06 28.8 0.7 0.061 13.7 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KPA45957.1 - 1.9e-06 27.5 1.3 0.012 15.3 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KPA45957.1 - 8.3e-06 25.8 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KPA45957.1 - 2.9e-05 24.1 0.3 0.055 13.6 0.1 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KPA45957.1 - 0.00013 21.9 0.4 0.23 11.2 0.1 3.9 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KPA45957.1 - 0.00024 20.8 0.2 0.36 10.4 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KPA45957.1 - 0.00034 20.9 0.1 0.52 10.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KPA45957.1 - 0.0022 18.2 0.0 5.1 7.4 0.0 3.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 KPA45957.1 - 0.0024 17.9 0.0 0.23 11.5 0.0 2.6 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 KPA45957.1 - 0.0057 16.8 3.1 0.018 15.1 0.7 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 KPA45957.1 - 0.0084 15.2 0.8 2.6 7.0 0.9 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.12 KPA45957.1 - 0.0087 16.0 0.1 4.2 7.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 KPA45957.1 - 0.01 15.2 0.2 0.071 12.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.9 KPA45957.1 - 0.011 15.0 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AIG1 PF04548.16 KPA45957.1 - 0.037 13.4 0.6 0.31 10.3 0.1 2.6 2 0 0 2 2 2 0 AIG1 family AAA_15 PF13175.6 KPA45957.1 - 0.048 13.4 0.0 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KPA45957.1 - 0.055 12.8 0.4 5.3 6.3 0.2 2.5 2 0 0 2 2 2 0 Zeta toxin DEAD PF00270.29 KPA45957.1 - 0.093 12.5 0.1 19 5.0 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_25 PF13481.6 KPA45957.1 - 0.12 11.9 0.1 0.78 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KPA45957.1 - 0.15 12.2 0.1 6.8 6.9 0.2 2.9 2 1 0 2 2 2 0 AAA domain CLP1_P PF16575.5 KPA45957.1 - 0.17 11.7 0.7 68 3.2 0.0 3.4 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 KPA45957.1 - 0.46 10.2 2.1 9 6.0 0.1 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein NB-ARC PF00931.22 KPA45957.1 - 0.47 9.6 1.6 14 4.7 0.1 2.8 4 0 0 4 4 4 0 NB-ARC domain Herpes_capsid PF06112.11 KPA45958.1 - 1.7 8.7 10.6 2.5 8.1 10.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ferric_reduct PF01794.19 KPA45959.1 - 3.3e-17 62.8 15.4 3.3e-17 62.8 15.4 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KPA45959.1 - 2.9e-12 46.6 0.0 5.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KPA45959.1 - 1.9e-07 31.3 0.0 2.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain PHO4 PF01384.20 KPA45960.1 - 0.018 14.1 2.9 0.022 13.8 2.9 1.1 1 0 0 1 1 1 0 Phosphate transporter family SLC35F PF06027.12 KPA45960.1 - 0.027 14.0 1.1 0.037 13.5 1.1 1.2 1 0 0 1 1 1 0 Solute carrier family 35 SirB PF04247.12 KPA45960.1 - 0.79 9.8 6.0 0.32 11.1 0.7 2.1 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB OPT PF03169.15 KPA45961.1 - 1.4e-156 522.7 43.6 1.6e-156 522.5 43.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TMA7 PF09072.10 KPA45962.1 - 6.5 7.7 10.4 6.4 7.7 1.3 2.3 2 0 0 2 2 2 0 Translation machinery associated TMA7 TMEM214 PF10151.9 KPA45962.1 - 9 4.6 5.7 15 3.9 5.7 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Peptidase_M24 PF00557.24 KPA45963.1 - 6.1e-42 143.7 0.1 8e-42 143.3 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Cyclin PF08613.11 KPA45966.1 - 1e-43 149.5 0.0 1.5e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin TPP_enzyme_N PF02776.18 KPA45967.1 - 1.4e-39 135.5 0.0 5.9e-38 130.2 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KPA45967.1 - 1.2e-21 77.1 0.1 2.7e-21 75.9 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPA45967.1 - 1.1e-13 51.1 0.0 5.3e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain FAD_binding_4 PF01565.23 KPA45968.1 - 1.6e-25 89.4 1.0 3.1e-25 88.5 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPA45968.1 - 3.9e-10 39.7 0.3 1.2e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like Fic PF02661.18 KPA45969.1 - 3.2e-20 72.8 0.0 6.1e-19 68.7 0.0 2.4 2 0 0 2 2 2 1 Fic/DOC family Pox_F17 PF04767.12 KPA45969.1 - 0.016 15.7 0.2 0.029 14.9 0.2 1.4 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein Catalase PF00199.19 KPA45970.1 - 4.1e-172 572.6 0.7 5.6e-172 572.1 0.7 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KPA45970.1 - 3e-16 59.4 0.1 5.9e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KPA45970.1 - 1.1e-08 34.8 0.1 3.5e-08 33.2 0.1 1.9 1 1 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KPA45970.1 - 3e-05 23.9 0.0 5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family XFP_C PF09363.10 KPA45971.1 - 6.8e-83 277.1 0.0 9.5e-83 276.6 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KPA45971.1 - 2e-78 262.1 0.0 3.5e-78 261.4 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_N PF09364.10 KPA45971.1 - 6.9e-58 196.2 0.0 1.7e-42 145.5 0.0 2.2 1 1 1 2 2 2 2 XFP N-terminal domain YrhK PF14145.6 KPA45971.1 - 0.15 11.9 0.0 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 YrhK-like protein Imm59 PF15597.6 KPA45972.1 - 0.019 15.4 1.0 0.057 13.9 0.6 2.0 1 1 1 2 2 2 0 Immunity protein 59 CMV_1a PF12467.8 KPA45972.1 - 8.1 6.8 7.1 15 5.9 1.9 2.3 1 1 1 2 2 2 0 Cucumber mosaic virus 1a protein family AA_permease_2 PF13520.6 KPA45973.1 - 2e-46 158.7 50.9 2.6e-46 158.3 50.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA45973.1 - 6.8e-27 94.2 43.3 8.6e-27 93.9 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease Myco_arth_vir_N PF09610.10 KPA45973.1 - 1.5 9.0 3.7 5.2 7.2 3.7 1.9 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Chitin_synth_2 PF03142.15 KPA45974.1 - 4.6e-42 144.3 0.1 8.5e-33 113.7 0.6 2.2 2 0 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 KPA45974.1 - 4.8e-10 39.5 0.0 0.00059 19.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KPA45974.1 - 3.8e-08 33.5 2.1 3.8e-08 33.5 2.1 3.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KPA45974.1 - 1.9e-06 27.9 0.0 0.0047 16.8 0.0 2.8 2 1 0 2 2 2 2 Glycosyltransferase like family 2 YiaAB PF05360.14 KPA45974.1 - 0.099 12.9 0.4 0.099 12.9 0.4 2.1 2 0 0 2 2 2 0 yiaA/B two helix domain Polysacc_deac_1 PF01522.21 KPA45975.1 - 1.7e-26 92.5 0.0 3.1e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KPA45975.1 - 2.4e-13 50.3 84.8 1.2e-05 25.7 16.5 4.1 4 0 0 4 4 4 3 Chitin recognition protein DUF2334 PF10096.9 KPA45975.1 - 0.021 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) UDPG_MGDP_dh PF00984.19 KPA45976.1 - 2.3e-20 72.6 0.0 7.6e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 KPA45976.1 - 3.1e-15 56.2 0.1 4.1e-13 49.3 0.1 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 KPA45976.1 - 7.8e-06 26.1 0.1 1.3e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 KPA45976.1 - 0.0028 18.1 0.0 0.0056 17.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TrkA_N PF02254.18 KPA45976.1 - 0.077 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 KPA45976.1 - 0.16 12.5 0.0 0.78 10.4 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent F-box-like PF12937.7 KPA45978.1 - 0.034 14.0 0.1 0.087 12.7 0.1 1.8 1 0 0 1 1 1 0 F-box-like Shisa PF13908.6 KPA45979.1 - 0.0021 18.3 0.1 0.0038 17.5 0.0 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 KPA45979.1 - 0.0023 17.7 2.7 0.004 16.9 2.7 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Gly-zipper_OmpA PF13436.6 KPA45979.1 - 0.0037 17.0 1.7 0.0062 16.3 1.7 1.2 1 0 0 1 1 1 1 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 KPA45979.1 - 0.031 14.0 1.5 0.052 13.3 1.5 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Mucin15 PF15672.5 KPA45979.1 - 0.033 13.7 0.9 0.06 12.8 0.9 1.4 1 1 0 1 1 1 0 Cell-membrane associated Mucin15 DUF456 PF04306.13 KPA45979.1 - 0.047 14.0 0.9 0.063 13.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) TMIE PF16038.5 KPA45979.1 - 0.06 13.2 0.8 0.096 12.5 0.8 1.3 1 0 0 1 1 1 0 TMIE protein EphA2_TM PF14575.6 KPA45979.1 - 0.091 13.7 0.0 0.12 13.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gly-zipper_Omp PF13488.6 KPA45979.1 - 0.096 12.7 2.5 0.14 12.1 2.5 1.3 1 0 0 1 1 1 0 Glycine zipper Tweety PF04906.13 KPA45979.1 - 0.16 10.6 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 Tweety Peptidase_M28 PF04389.17 KPA45980.1 - 2.3e-41 141.7 0.0 4.3e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KPA45980.1 - 1.1e-09 38.1 0.1 2.2e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KPA45980.1 - 0.00028 20.6 0.0 0.00053 19.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 PALP PF00291.25 KPA45981.1 - 2.3e-64 217.6 0.0 3e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KPA45981.1 - 2.4e-12 47.1 0.0 9.2e-09 35.6 0.0 3.2 3 0 0 3 3 3 2 CBS domain SRPRB PF09439.10 KPA45982.1 - 7.3e-31 107.0 0.0 1.9e-30 105.6 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPA45982.1 - 2.2e-07 31.0 0.1 3.4e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KPA45982.1 - 1.4e-06 27.9 0.0 1.8e-05 24.3 0.0 2.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPA45982.1 - 5e-05 22.9 0.1 0.00014 21.5 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KPA45982.1 - 0.001 18.9 0.0 0.0091 15.8 0.0 2.0 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 KPA45982.1 - 0.0015 17.9 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KPA45982.1 - 0.0051 17.0 0.1 0.018 15.2 0.1 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KPA45982.1 - 0.012 16.0 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KPA45982.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Ras PF00071.22 KPA45982.1 - 0.018 14.7 0.0 0.087 12.4 0.0 2.0 1 1 0 1 1 1 0 Ras family Septin PF00735.18 KPA45982.1 - 0.037 13.3 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Septin cobW PF02492.19 KPA45982.1 - 0.049 13.2 0.6 0.73 9.4 0.0 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DHHC PF01529.20 KPA45983.1 - 5.8e-34 117.1 15.8 5.8e-34 117.1 15.8 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KPA45983.1 - 3e-29 101.4 0.0 4.8e-14 52.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA45983.1 - 1.1e-24 86.5 1.2 1e-07 32.3 0.1 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA45983.1 - 6.2e-23 78.4 0.8 3e-07 30.2 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KPA45983.1 - 6.6e-23 80.1 0.2 1.5e-05 25.2 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KPA45983.1 - 3.3e-22 78.2 0.0 9.1e-06 25.9 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) DUF3251 PF11622.8 KPA45983.1 - 0.14 11.8 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) PocR PF10114.9 KPA45983.1 - 0.38 10.5 3.3 0.76 9.5 3.3 1.4 1 0 0 1 1 1 0 Sensory domain found in PocR Pyr_redox_3 PF13738.6 KPA45985.1 - 6.9e-15 55.1 0.0 4e-13 49.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPA45985.1 - 5.4e-14 51.5 0.1 7.6e-13 47.7 0.1 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPA45985.1 - 7.4e-11 41.8 0.0 3.8e-09 36.2 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA45985.1 - 1.9e-09 37.1 0.0 4.7e-06 26.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPA45985.1 - 7.6e-06 26.1 0.6 3e-05 24.2 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA45985.1 - 1.3e-05 24.9 0.0 6.6e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPA45985.1 - 0.00012 22.5 1.2 0.18 12.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KPA45985.1 - 0.0051 16.9 0.1 6 6.9 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KPA45985.1 - 0.0075 15.6 0.8 0.11 11.8 0.4 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KPA45985.1 - 0.011 15.6 0.5 0.018 14.9 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KPA45985.1 - 0.018 15.0 2.6 0.4 10.7 0.3 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KPA45985.1 - 0.047 12.8 1.2 0.077 12.1 1.2 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KPA45985.1 - 0.064 13.7 0.0 0.56 10.7 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KPA45985.1 - 0.23 10.1 1.7 0.39 9.3 0.5 1.8 2 0 0 2 2 2 0 HI0933-like protein Aa_trans PF01490.18 KPA45987.1 - 2.1e-53 181.5 35.7 2.4e-53 181.3 35.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein COX2_TM PF02790.15 KPA45987.1 - 0.025 14.7 0.9 0.025 14.7 0.9 3.2 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain DAO PF01266.24 KPA45988.1 - 7.9e-41 140.8 0.2 1.1e-40 140.4 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA45988.1 - 8.8e-08 31.7 0.0 0.0086 15.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPA45988.1 - 1.3e-05 24.5 0.1 0.021 13.9 0.0 2.7 3 1 1 4 4 4 2 FAD binding domain GIDA PF01134.22 KPA45988.1 - 4.5e-05 22.7 0.0 0.013 14.6 0.0 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KPA45988.1 - 0.00011 22.4 0.0 0.00028 21.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPA45988.1 - 0.00013 20.9 0.0 0.065 11.9 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KPA45988.1 - 0.00037 19.9 0.0 0.0047 16.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPA45988.1 - 0.0021 17.3 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KPA45988.1 - 0.0054 16.7 0.3 2.3 8.2 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KPA45988.1 - 0.011 16.3 0.0 0.058 14.0 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KPA45988.1 - 0.043 13.3 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Amino_oxidase PF01593.24 KPA45988.1 - 0.059 12.6 0.0 6.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 KPA45988.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KPA45988.1 - 0.065 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HAUS-augmin3 PF14932.6 KPA45990.1 - 0.0091 15.6 9.9 0.0091 15.6 9.9 3.5 2 1 2 4 4 4 1 HAUS augmin-like complex subunit 3 Herpes_ICP4_N PF03584.15 KPA45990.1 - 0.067 13.0 0.1 0.65 9.8 0.2 2.4 2 1 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region DUF16 PF01519.16 KPA45990.1 - 0.57 10.7 17.2 1.7 9.2 1.3 3.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF4061 PF13270.6 KPA45990.1 - 0.81 10.0 11.9 0.072 13.4 2.8 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4061) DASH_Dam1 PF08653.10 KPA45990.1 - 0.92 9.4 4.7 4.2 7.3 0.1 3.8 5 0 0 5 5 5 0 DASH complex subunit Dam1 DUF1759 PF03564.15 KPA45990.1 - 1.2 9.1 5.9 2.8 7.9 0.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Spc7 PF08317.11 KPA45990.1 - 1.2 7.9 26.9 1.4 7.7 5.0 2.8 2 1 2 4 4 4 0 Spc7 kinetochore protein ERM PF00769.19 KPA45990.1 - 3.3 7.5 25.7 11 5.7 25.5 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family ApoLp-III PF07464.11 KPA45990.1 - 7.5 6.6 18.7 2.2 8.4 3.8 4.3 2 2 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) STAT_alpha PF01017.20 KPA45990.1 - 9.6 6.1 19.8 3.7 7.4 12.2 3.0 3 1 0 3 3 3 0 STAT protein, all-alpha domain LrgB PF04172.16 KPA45991.1 - 2.2e-24 86.2 5.9 3.3e-16 59.5 0.7 2.6 2 0 0 2 2 2 2 LrgB-like family DUF4212 PF13937.6 KPA45991.1 - 0.019 15.3 3.1 0.019 15.3 3.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Cytochrome-c551 PF10643.9 KPA45991.1 - 9.6 5.7 7.0 3.8 7.0 3.3 2.1 1 1 1 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Rotamase PF00639.21 KPA45992.1 - 3.4e-21 76.0 0.0 4.8e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KPA45992.1 - 4.9e-15 56.1 0.0 6.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KPA45992.1 - 8e-08 32.2 1.9 8.9e-08 32.1 0.5 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KPA45992.1 - 0.0081 17.0 0.0 0.01 16.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 KPA45992.1 - 0.016 14.9 0.4 0.035 13.8 0.4 1.6 1 0 0 1 1 1 0 WW domain RNA_POL_M_15KD PF02150.16 KPA45993.1 - 2.8e-11 43.1 2.5 2.8e-11 43.1 2.5 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 KPA45993.1 - 0.0096 16.2 8.0 0.49 10.8 0.1 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme MqsA_antitoxin PF15731.5 KPA45993.1 - 2.4 8.2 4.6 0.58 10.3 0.3 2.0 1 1 1 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA DZR PF12773.7 KPA45993.1 - 3.9 7.6 15.3 0.27 11.3 2.9 2.9 2 1 0 2 2 2 0 Double zinc ribbon zf-ACC PF17848.1 KPA45993.1 - 7.4 6.7 10.7 2.6 8.2 0.1 3.6 3 1 1 4 4 4 0 Acetyl-coA carboxylase zinc finger domain TFIIS_C PF01096.18 KPA45994.1 - 2.5e-16 59.2 5.9 2.5e-16 59.2 5.9 2.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_ribbon_17 PF17120.5 KPA45994.1 - 0.008 15.8 5.7 0.14 11.8 0.4 2.2 2 0 0 2 2 2 2 Zinc-ribbon, C4HC2 type Apo-CIII PF05778.12 KPA45994.1 - 0.08 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Lar_restr_allev PF14354.6 KPA45994.1 - 0.082 13.3 2.4 0.14 12.6 2.4 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar UPF0547 PF10571.9 KPA45994.1 - 0.12 12.5 11.0 0.12 12.5 0.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.10 KPA45994.1 - 1.5 9.0 9.0 5.7 7.1 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Ribosomal_L14 PF00238.19 KPA45995.1 - 2.4e-46 156.8 1.3 2.8e-46 156.6 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.28 KPA45996.1 - 2.5e-10 41.0 0.1 9.6e-10 39.1 0.0 2.0 2 1 0 2 2 2 1 SET domain Tmemb_55A PF09788.9 KPA45996.1 - 0.022 13.9 0.1 0.065 12.3 0.1 1.7 1 0 0 1 1 1 0 Transmembrane protein 55A FAM76 PF16046.5 KPA45996.1 - 0.036 13.4 0.6 0.036 13.4 0.6 2.7 3 0 0 3 3 3 0 FAM76 protein SPATIAL PF15256.6 KPA45996.1 - 5.1 7.4 10.4 5.8 7.2 4.9 2.6 2 0 0 2 2 2 0 SPATIAL Oxidored_FMN PF00724.20 KPA45997.1 - 1.4e-66 225.2 0.0 1.7e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_M28 PF04389.17 KPA45999.1 - 9.8e-38 129.8 0.0 1.4e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KPA45999.1 - 8.4e-11 41.8 0.2 2.2e-10 40.4 0.2 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KPA45999.1 - 0.0023 17.7 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 zf-RING_UBOX PF13445.6 KPA46001.1 - 6.6e-06 26.1 3.6 6.9e-06 26.0 2.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KPA46001.1 - 1.6e-05 24.7 5.0 1.6e-05 24.7 5.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPA46001.1 - 0.0002 21.1 10.7 0.0028 17.5 6.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPA46001.1 - 0.00051 19.8 14.0 0.017 15.0 9.5 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KPA46001.1 - 0.0047 16.9 12.3 0.0047 16.9 12.3 2.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 KPA46001.1 - 0.0064 16.8 13.5 0.15 12.4 13.5 2.5 1 1 0 1 1 1 1 Ring finger domain Pellino PF04710.14 KPA46001.1 - 0.068 11.8 1.8 0.11 11.1 1.8 1.2 1 0 0 1 1 1 0 Pellino zf-C3HC4_4 PF15227.6 KPA46001.1 - 0.12 12.6 8.2 0.36 11.0 4.4 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KPA46001.1 - 0.61 10.0 15.5 0.51 10.2 5.9 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KPA46001.1 - 1.6 8.8 12.0 49 4.1 0.2 3.0 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 KPA46001.1 - 5.7 6.8 9.9 2.9 7.7 2.8 3.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Chorismate_bind PF00425.18 KPA46002.1 - 6e-87 291.5 0.0 1.3e-84 283.8 0.0 2.9 2 1 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 KPA46002.1 - 1.7e-31 109.3 0.0 2.8e-27 95.7 0.0 3.0 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region BTB PF00651.31 KPA46003.1 - 1.7e-07 31.4 0.0 6e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain 4HBT PF03061.22 KPA46004.1 - 5.2e-12 46.0 0.7 7.4e-12 45.5 0.2 1.5 2 0 0 2 2 2 1 Thioesterase superfamily DUF1993 PF09351.10 KPA46005.1 - 1.3e-37 129.4 0.1 6.9e-33 114.1 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF1993) Glyoxalase_3 PF13468.6 KPA46006.1 - 9.7e-14 51.9 0.0 1.4e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain zf-RING_5 PF14634.6 KPA46007.1 - 2e-05 24.4 3.2 2e-05 24.4 3.2 2.0 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KPA46007.1 - 3.8e-05 23.5 3.6 0.00075 19.3 1.9 2.9 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KPA46007.1 - 0.00085 19.6 4.8 0.00085 19.6 4.8 2.4 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 KPA46007.1 - 0.009 15.8 8.8 0.0096 15.8 0.7 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA46007.1 - 0.027 14.5 12.7 0.22 11.6 1.8 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KPA46007.1 - 0.051 13.5 5.2 0.16 11.9 3.0 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPA46007.1 - 0.13 12.1 4.3 4.5 7.2 0.4 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPA46007.1 - 0.23 11.6 11.0 1.3 9.3 0.1 3.1 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING adh_short_C2 PF13561.6 KPA46008.1 - 6.4e-59 199.3 0.8 8e-59 199.0 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA46008.1 - 2.4e-42 144.6 0.5 3.1e-42 144.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA46008.1 - 5.6e-05 23.1 0.1 9.2e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF4501 PF14946.6 KPA46008.1 - 0.026 14.6 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) NusB PF01029.18 KPA46008.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 NusB family ILVD_EDD PF00920.21 KPA46009.1 - 2.3e-154 514.9 0.2 2.6e-154 514.7 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Fungal_trans PF04082.18 KPA46010.1 - 1.9e-20 73.0 0.1 2.9e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ldh_2 PF02615.14 KPA46011.1 - 4.2e-123 410.7 0.7 4.8e-123 410.6 0.7 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase NicO PF03824.16 KPA46013.1 - 5.1e-69 232.8 9.4 6.8e-69 232.3 9.4 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein Dabb PF07876.12 KPA46014.1 - 5.3e-13 49.4 0.1 8.9e-13 48.7 0.1 1.4 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Peptidase_C2 PF00648.21 KPA46015.1 - 1.9e-59 201.1 0.3 5.4e-58 196.4 0.3 2.4 1 1 0 1 1 1 1 Calpain family cysteine protease RF3_C PF16658.5 KPA46015.1 - 0.17 11.7 3.2 0.56 10.0 3.2 1.9 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain APG17 PF04108.12 KPA46016.1 - 2.6e-130 435.1 6.8 3.1e-130 434.9 6.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DEAD PF00270.29 KPA46016.1 - 0.006 16.4 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Bacillus_HBL PF05791.11 KPA46016.1 - 0.11 12.3 1.4 1 9.2 0.0 2.8 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) NAD_binding_2 PF03446.15 KPA46016.1 - 0.12 12.5 0.2 2.5 8.3 0.0 2.4 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Choline_transpo PF04515.12 KPA46017.1 - 2.5e-87 293.1 23.8 2.5e-87 293.1 23.8 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 KPA46017.1 - 0.45 11.2 3.0 1.1 9.9 3.0 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ferlin_C PF16165.5 KPA46017.1 - 1.1 9.2 3.9 3.1 7.7 3.9 1.7 1 0 0 1 1 1 0 Ferlin C-terminus Deltameth_res PF16020.5 KPA46017.1 - 1.1 9.2 0.0 1.1 9.2 0.0 4.5 5 0 0 5 5 5 0 Deltamethrin resistance AA_permease PF00324.21 KPA46018.1 - 5.3e-130 434.2 45.0 6.4e-130 433.9 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPA46018.1 - 1.5e-33 116.3 50.5 1.9e-33 115.9 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.28 KPA46019.1 - 1.5e-76 257.7 0.0 4.1e-76 256.3 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KPA46019.1 - 7.5e-60 202.3 0.0 3.5e-59 200.0 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 KPA46019.1 - 7e-53 179.0 4.1 3.4e-52 176.8 4.1 2.2 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA46019.1 - 1e-40 139.8 2.0 2.1e-40 138.7 2.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA46019.1 - 1.3e-18 67.5 2.8 1.3e-15 57.8 1.9 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KPA46019.1 - 1.3e-17 64.1 0.0 1.4e-09 37.8 0.0 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KPA46019.1 - 9.9e-12 45.0 0.0 2.6e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 KPA46019.1 - 5.4e-09 36.2 0.5 1.3e-06 28.5 1.1 3.2 4 0 0 4 4 4 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KPA46019.1 - 2.3e-07 30.2 2.1 0.00017 20.8 0.1 3.4 3 1 0 3 3 3 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 KPA46019.1 - 2.7e-07 29.9 0.1 0.011 14.8 0.0 3.1 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KPA46019.1 - 7.7e-07 28.5 4.2 8.7e-05 21.8 0.7 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein AMP-binding_C PF13193.6 KPA46019.1 - 1.3e-05 26.1 0.1 7.5e-05 23.6 0.1 2.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KPA46019.1 - 0.00034 20.1 0.1 0.2 11.0 0.0 2.7 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KPA46019.1 - 0.0022 17.3 0.4 0.0054 16.1 0.4 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 KPA46019.1 - 0.018 14.6 4.0 0.72 9.4 2.6 2.6 2 0 0 2 2 2 0 NmrA-like family ApbA PF02558.16 KPA46019.1 - 0.079 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LPMO_10 PF03067.15 KPA46020.1 - 5.2e-13 50.1 0.1 5.2e-13 50.1 0.1 1.7 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading BSP_II PF05432.11 KPA46020.1 - 0.35 10.5 13.0 0.62 9.7 13.0 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC27 PF09507.10 KPA46020.1 - 0.46 9.8 9.0 0.63 9.4 9.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RdRP PF05183.12 KPA46022.1 - 7.9e-127 424.3 0.1 1.9e-126 423.1 0.0 1.6 2 0 0 2 2 2 1 RNA dependent RNA polymerase DUF2959 PF11172.8 KPA46022.1 - 0.11 12.7 5.5 0.028 14.6 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2959) DUF5093 PF17011.5 KPA46022.1 - 0.13 12.6 1.7 0.25 11.6 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) Fungal_trans PF04082.18 KPA46023.1 - 3e-18 65.8 1.0 5.4e-18 65.0 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA46023.1 - 5.7e-08 32.8 13.6 1.1e-07 31.8 13.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIO1 PF01163.22 KPA46024.1 - 1e-70 237.2 0.8 1.7e-70 236.4 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KPA46024.1 - 0.00098 19.1 0.0 0.95 9.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KPA46024.1 - 0.038 13.4 0.1 4.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp PF00026.23 KPA46025.1 - 6.8e-64 216.3 2.2 8.2e-64 216.0 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPA46025.1 - 5.1e-09 36.6 1.2 4.5e-07 30.3 0.6 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KPA46025.1 - 0.012 15.5 0.0 0.055 13.2 0.0 2.1 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KPA46025.1 - 0.029 15.0 0.1 31 5.3 0.0 3.4 2 1 0 2 2 2 0 Aspartyl protease NmrA PF05368.13 KPA46026.1 - 1.9e-20 73.4 0.0 2.4e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPA46026.1 - 8.1e-07 29.1 0.1 1.6e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPA46026.1 - 1.5e-05 25.3 0.3 3.5e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KPA46026.1 - 5e-05 23.4 0.3 0.0012 18.9 0.3 2.6 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KPA46026.1 - 0.00031 20.3 0.0 0.00058 19.4 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Glyco_trans_1_4 PF13692.6 KPA46026.1 - 0.068 13.6 0.1 0.15 12.5 0.1 1.6 1 1 0 1 1 1 0 Glycosyl transferases group 1 Pyr_redox_2 PF07992.14 KPA46028.1 - 3.2e-15 56.1 0.1 5.3e-15 55.4 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA46028.1 - 1.1e-05 24.7 1.4 0.00032 19.8 0.1 2.9 2 1 1 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KPA46028.1 - 2.1e-05 23.9 0.4 0.0004 19.7 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPA46028.1 - 2.2e-05 24.6 0.0 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KPA46028.1 - 9.9e-05 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KPA46028.1 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA46028.1 - 0.00046 19.9 0.4 0.00074 19.2 0.4 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPA46028.1 - 0.00068 18.5 0.0 0.0015 17.3 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KPA46028.1 - 0.00071 18.9 0.3 0.0099 15.1 0.1 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KPA46028.1 - 0.006 15.7 0.2 0.13 11.3 0.1 2.2 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KPA46028.1 - 0.011 15.8 0.4 0.32 11.0 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KPA46028.1 - 0.013 14.8 0.1 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KPA46028.1 - 0.019 15.5 0.9 1.4 9.5 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA46028.1 - 0.096 11.8 0.1 3.1 6.8 0.1 2.3 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Hydrolase_4 PF12146.8 KPA46029.1 - 9.7e-08 31.6 0.0 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA46029.1 - 1.5e-07 32.2 0.2 2.4e-07 31.6 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA46029.1 - 0.051 13.2 0.1 0.15 11.7 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_M24 PF00557.24 KPA46030.1 - 8.5e-56 188.9 0.0 1.2e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KPA46030.1 - 7.5e-26 90.3 0.0 1.5e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Flavokinase PF01687.17 KPA46031.1 - 7.5e-12 45.5 0.0 1.3e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase CBM_21 PF03370.13 KPA46033.1 - 1.6e-33 115.3 0.2 2.6e-33 114.5 0.2 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KPA46033.1 - 4.7e-10 39.9 0.5 1.1e-09 38.7 0.5 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Methyltransf_34 PF11312.8 KPA46034.1 - 1.3e-78 264.4 0.0 1.6e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Cauli_VI PF01693.16 KPA46035.1 - 7.3e-08 32.6 0.4 1.3e-07 31.8 0.4 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin zf-CCHC PF00098.23 KPA46036.1 - 0.00025 21.0 3.1 0.00025 21.0 3.1 2.3 2 0 0 2 2 2 1 Zinc knuckle MCM_OB PF17207.3 KPA46036.1 - 1.5 8.7 4.2 2.1 8.2 2.2 2.2 2 0 0 2 2 2 0 MCM OB domain zf-CCHC_3 PF13917.6 KPA46036.1 - 4.5 7.3 10.6 18 5.4 10.6 2.0 1 1 0 1 1 1 0 Zinc knuckle DUF1610 PF07754.11 KPA46036.1 - 4.8 7.2 6.5 0.36 10.8 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) RVT_1 PF00078.27 KPA46037.1 - 4.6e-37 127.7 0.0 7e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KPA46037.1 - 3.3e-15 56.0 0.0 1.8e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KPA46037.1 - 0.0089 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 KPA46040.1 - 5.7e-30 104.4 23.5 8.9e-30 103.8 23.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily AA_permease_2 PF13520.6 KPA46041.1 - 4.9e-44 150.8 55.3 6.1e-44 150.5 55.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA46041.1 - 9.1e-32 110.3 50.7 1.1e-31 109.9 50.7 1.0 1 0 0 1 1 1 1 Amino acid permease HR_lesion PF05514.11 KPA46041.1 - 0.12 12.6 0.0 0.12 12.6 0.0 2.2 3 0 0 3 3 3 0 HR-like lesion-inducing Cofilin_ADF PF00241.20 KPA46042.1 - 2.9e-23 82.0 0.0 3.2e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Scytalone_dh PF02982.14 KPA46043.1 - 2.3e-60 203.0 0.2 2.7e-60 202.8 0.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KPA46043.1 - 3e-09 37.1 0.4 3.7e-09 36.8 0.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain Pyr_redox_2 PF07992.14 KPA46044.1 - 9.2e-14 51.4 0.0 1.6e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPA46044.1 - 1.6e-11 44.1 0.5 2.1e-09 37.1 0.2 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA46044.1 - 6.7e-11 41.9 0.1 3.9e-09 36.1 0.0 2.5 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KPA46044.1 - 2.7e-10 39.3 0.0 7.3e-10 37.9 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 KPA46044.1 - 4.7e-06 26.0 0.1 0.01 15.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 KPA46044.1 - 2.5e-05 24.8 0.4 0.013 16.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SnoaL_2 PF12680.7 KPA46044.1 - 4.8e-05 23.9 0.4 0.00012 22.6 0.4 1.7 1 0 0 1 1 1 1 SnoaL-like domain NAD_binding_8 PF13450.6 KPA46044.1 - 6e-05 23.2 0.0 0.00097 19.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SnoaL_4 PF13577.6 KPA46044.1 - 0.00014 22.0 0.3 0.002 18.3 0.1 2.3 2 0 0 2 2 2 1 SnoaL-like domain FAD_binding_2 PF00890.24 KPA46044.1 - 0.0058 15.8 1.4 0.19 10.7 0.3 2.8 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.20 KPA46044.1 - 0.0059 16.7 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KPA46044.1 - 0.0065 15.8 0.1 5.7 6.1 0.7 3.0 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 KPA46044.1 - 0.009 15.4 0.5 0.019 14.3 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KPA46044.1 - 0.03 13.9 0.5 1.1 8.7 0.3 3.0 3 1 1 4 4 4 0 FAD dependent oxidoreductase DUF4440 PF14534.6 KPA46044.1 - 0.043 14.2 0.2 0.12 12.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) HI0933_like PF03486.14 KPA46044.1 - 0.12 11.1 0.3 0.26 10.0 0.3 1.5 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KPA46044.1 - 0.15 11.3 0.2 0.45 9.8 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ANAPC4_WD40 PF12894.7 KPA46046.1 - 2e-11 44.0 0.0 0.037 14.3 0.0 6.9 4 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPA46046.1 - 0.00013 22.7 0.0 2.5 9.1 0.0 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat YqgC PF17430.2 KPA46046.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized YqgC-like ANAPC_CDC26 PF10471.9 KPA46048.1 - 4e-12 46.8 7.0 6.8e-12 46.0 7.0 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Ribosomal_60s PF00428.19 KPA46048.1 - 0.014 15.9 2.3 0.017 15.7 2.3 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Metallophos PF00149.28 KPA46049.1 - 1.5e-07 32.1 8.0 4.5e-07 30.6 8.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S18 PF01084.20 KPA46050.1 - 0.031 14.5 0.4 0.099 12.9 0.4 1.8 1 0 0 1 1 1 0 Ribosomal protein S18 IF4E PF01652.18 KPA46052.1 - 6.9e-55 185.2 0.1 8.5e-55 184.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.28 KPA46053.1 - 2e-69 234.2 0.0 2.8e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA46053.1 - 1.5e-12 48.3 0.1 3e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Beta-TrCP_D PF12125.8 KPA46053.1 - 0.41 10.6 1.0 1.2 9.0 1.2 1.7 2 0 0 2 2 2 0 D domain of beta-TrCP BolA PF01722.18 KPA46054.1 - 3.5e-31 107.3 2.0 4.5e-31 106.9 2.0 1.1 1 0 0 1 1 1 1 BolA-like protein PIP5K PF01504.18 KPA46056.1 - 9.6e-32 110.3 6.5 2.9e-24 85.7 0.2 3.4 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KPA46056.1 - 3.9e-27 95.0 0.0 6.4e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KPA46056.1 - 2.1e-14 53.4 10.1 5.8e-14 52.0 10.1 1.8 1 0 0 1 1 1 1 FYVE zinc finger MMM1 PF10296.9 KPA46057.1 - 1.1e-06 28.0 0.0 1.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 VPS28 PF03997.12 KPA46058.1 - 1.1e-67 227.4 0.0 1.3e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.13 KPA46059.1 - 1.8e-127 424.7 0.1 2.9e-127 424.0 0.1 1.3 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 KPA46059.1 - 2.3e-07 29.5 0.2 2.3e-07 29.5 0.2 3.7 2 2 1 3 3 3 1 Nop14-like family Cep57_CLD_2 PF14197.6 KPA46060.1 - 4e-27 94.1 68.4 1.5e-16 60.2 15.2 6.9 6 2 2 8 8 5 3 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.13 KPA46060.1 - 4.7e-27 94.2 0.2 4.7e-27 94.2 0.2 6.2 5 1 1 6 6 5 1 Centrosome microtubule-binding domain of Cep57 KASH_CCD PF14662.6 KPA46060.1 - 3.8e-05 23.6 23.8 8.7e-05 22.4 16.2 5.8 3 1 3 6 6 5 3 Coiled-coil region of CCDC155 or KASH PRKG1_interact PF15898.5 KPA46060.1 - 0.0022 18.9 9.6 0.0022 18.9 9.6 7.5 4 3 2 7 7 5 2 cGMP-dependent protein kinase interacting domain GAS PF13851.6 KPA46060.1 - 0.0062 15.9 15.3 0.0062 15.9 15.3 5.4 3 1 3 6 6 6 3 Growth-arrest specific micro-tubule binding HALZ PF02183.18 KPA46060.1 - 0.0064 16.7 0.7 0.0064 16.7 0.7 8.8 7 1 1 9 9 9 3 Homeobox associated leucine zipper bZIP_1 PF00170.21 KPA46060.1 - 0.012 15.6 2.7 0.012 15.6 2.7 8.2 3 2 5 8 8 8 0 bZIP transcription factor DUF2968 PF11180.8 KPA46060.1 - 0.015 14.9 0.8 0.015 14.9 0.8 6.1 5 1 2 7 7 6 0 Protein of unknown function (DUF2968) DUF1664 PF07889.12 KPA46060.1 - 0.059 13.4 24.4 0.23 11.5 2.0 5.1 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 KPA46060.1 - 0.12 12.6 47.3 3.2 8.0 4.6 7.5 4 2 1 5 5 5 0 Centrosomin N-terminal motif 1 Bap31_Bap29_C PF18035.1 KPA46060.1 - 0.28 11.2 27.6 0.49 10.4 0.5 6.5 6 0 0 6 6 6 0 Bap31/Bap29 cytoplasmic coiled-coil domain JIP_LZII PF16471.5 KPA46060.1 - 0.59 10.3 46.9 0.24 11.6 4.8 7.2 2 1 4 6 6 6 0 JNK-interacting protein leucine zipper II RasGEF_N_2 PF14663.6 KPA46060.1 - 1.3 9.4 5.3 0.66 10.4 0.4 2.8 3 0 0 3 3 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain WXG100 PF06013.12 KPA46060.1 - 1.9 8.8 21.6 8.3 6.7 0.0 6.3 4 2 1 5 5 5 0 Proteins of 100 residues with WXG DUF730 PF05325.11 KPA46060.1 - 2.3 8.2 8.0 27 4.8 0.1 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF730) SOAR PF16533.5 KPA46060.1 - 6.9 6.7 19.9 0.43 10.6 4.0 4.9 2 1 1 3 3 3 0 STIM1 Orai1-activating region Glyco_hydro_76 PF03663.14 KPA46061.1 - 6.1e-21 75.3 0.3 4.6e-20 72.5 0.3 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 PALP PF00291.25 KPA46063.1 - 1.1e-76 258.1 0.1 1.5e-76 257.7 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KPA46063.1 - 1.6e-40 136.7 0.0 6.9e-19 67.4 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase ING PF12998.7 KPA46064.1 - 1.6e-07 31.9 0.1 0.0003 21.3 0.0 2.6 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KPA46064.1 - 1.3e-06 28.1 7.8 2.3e-06 27.4 7.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KPA46064.1 - 0.24 11.7 1.4 0.6 10.4 1.4 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prenyltransf PF01255.19 KPA46065.1 - 2.3e-82 275.9 0.0 3.4e-82 275.3 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Glyco_hydro_63 PF03200.16 KPA46066.1 - 2.6e-07 29.8 9.7 2e-06 26.9 0.1 4.0 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain 1-cysPrx_C PF10417.9 KPA46066.1 - 0.092 12.6 1.3 0.21 11.4 1.3 1.6 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin OSCP PF00213.18 KPA46067.1 - 1e-46 159.2 3.8 1.2e-46 159.0 3.8 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Mob1_phocein PF03637.17 KPA46068.1 - 3.8e-69 232.0 0.0 5.3e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family DBR1 PF05011.13 KPA46069.1 - 2.4e-48 164.1 0.2 6.3e-47 159.5 0.0 2.2 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KPA46069.1 - 2.9e-05 24.7 0.8 5.1e-05 23.9 0.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Skp1_POZ PF03931.15 KPA46070.1 - 2.1e-07 31.0 0.0 3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ras PF00071.22 KPA46071.1 - 1.6e-48 164.4 0.0 2.2e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPA46071.1 - 9e-21 74.3 0.0 2.3e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA46071.1 - 5.4e-06 26.0 0.0 1.4e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KPA46071.1 - 0.047 13.1 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KPA46071.1 - 0.084 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region CAP PF00188.26 KPA46071.1 - 0.12 13.2 0.0 0.45 11.3 0.0 1.9 2 0 0 2 2 2 0 Cysteine-rich secretory protein family Abdominal-A PF12407.8 KPA46071.1 - 0.26 10.9 2.6 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Homeobox protein GrpE PF01025.19 KPA46072.1 - 6.2e-48 162.6 5.2 8.1e-48 162.2 5.2 1.2 1 0 0 1 1 1 1 GrpE Prominin PF05478.11 KPA46072.1 - 0.086 10.8 0.1 0.1 10.5 0.1 1.1 1 0 0 1 1 1 0 Prominin RPN6_N PF18055.1 KPA46073.1 - 1.9e-44 150.7 3.1 1.9e-44 150.7 3.1 2.5 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KPA46073.1 - 4.6e-20 72.1 1.5 9.8e-20 71.0 0.2 2.3 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 KPA46073.1 - 3.8e-10 39.3 2.1 7.1e-10 38.4 0.8 2.2 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 KPA46073.1 - 8.5e-05 22.3 0.7 0.38 10.9 0.2 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KPA46073.1 - 0.00011 21.8 2.3 0.00011 21.8 2.3 2.8 2 1 1 3 3 3 1 MalT-like TPR region DDRGK PF09756.9 KPA46073.1 - 0.00016 21.3 0.1 0.00016 21.3 0.1 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_12 PF13424.6 KPA46073.1 - 0.0068 16.7 17.7 0.084 13.2 1.4 5.2 6 1 1 7 7 7 2 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 KPA46073.1 - 0.011 15.7 0.2 0.19 11.8 0.0 2.7 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain TPR_2 PF07719.17 KPA46073.1 - 0.013 15.6 1.1 30 5.0 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat DprA_WH PF17782.1 KPA46073.1 - 0.065 13.4 0.2 0.52 10.5 0.0 2.5 3 0 0 3 3 3 0 DprA winged helix domain TPR_14 PF13428.6 KPA46073.1 - 0.39 11.7 7.6 5.1 8.2 0.0 5.0 5 1 1 6 6 5 0 Tetratricopeptide repeat MetRS-N PF09635.10 KPA46073.1 - 0.41 11.2 0.1 0.41 11.2 0.1 3.1 3 1 1 4 4 4 0 MetRS-N binding domain TPR_6 PF13174.6 KPA46073.1 - 1.6 9.6 7.2 31 5.5 0.1 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPA46073.1 - 7.5 7.3 8.4 13 6.6 0.2 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat AT_hook PF02178.19 KPA46074.1 - 0.014 15.2 17.3 1.1 9.4 5.8 3.8 2 0 0 2 2 2 0 AT hook motif Mito_carr PF00153.27 KPA46075.1 - 2.9e-50 168.2 4.6 4.4e-16 58.6 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPA46075.1 - 0.062 12.4 1.4 4.2 6.4 0.0 3.0 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Wzz PF02706.15 KPA46075.1 - 0.097 13.0 0.9 1.2 9.5 0.1 2.7 3 0 0 3 3 3 0 Chain length determinant protein Mak10 PF04112.13 KPA46076.1 - 1.7e-64 216.4 0.0 3.2e-64 215.5 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase YbjN PF10722.9 KPA46076.1 - 0.085 12.9 0.0 0.25 11.4 0.0 1.8 1 1 0 1 1 1 0 Putative bacterial sensory transduction regulator ATP-synt_Eps PF04627.13 KPA46077.1 - 1.3e-24 85.9 1.6 2e-24 85.3 1.6 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain LtrA PF06772.11 KPA46078.1 - 2.8e-63 214.3 21.6 3.4e-63 214.0 21.6 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Fungal_trans_2 PF11951.8 KPA46080.1 - 1.1e-06 27.8 0.4 1.7e-06 27.1 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_cc PF11790.8 KPA46081.1 - 2.8e-50 171.1 0.1 2.8e-50 171.1 0.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core CDC27 PF09507.10 KPA46081.1 - 0.2 11.0 8.5 0.28 10.5 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-RING_2 PF13639.6 KPA46082.1 - 8.5e-13 48.4 6.2 1.4e-12 47.7 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KPA46082.1 - 3.8e-11 42.5 3.2 8.6e-11 41.4 3.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KPA46082.1 - 4.6e-08 32.8 5.8 7.5e-08 32.1 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA46082.1 - 1.3e-07 31.3 4.1 2.3e-07 30.6 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KPA46082.1 - 2.6e-06 27.6 6.7 9.2e-06 25.9 6.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KPA46082.1 - 7.6e-06 25.7 3.7 1.4e-05 24.8 3.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KPA46082.1 - 8.1e-06 25.7 3.2 1.3e-05 25.0 3.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KPA46082.1 - 0.00053 19.8 2.1 0.00093 19.0 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KPA46082.1 - 0.0027 17.7 2.7 0.0089 16.1 2.7 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KPA46082.1 - 0.0035 17.3 2.5 0.0035 17.3 2.5 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-HC5HC2H_2 PF13832.6 KPA46082.1 - 0.035 14.3 0.1 0.071 13.3 0.1 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.6 KPA46082.1 - 0.041 13.7 3.6 0.078 12.8 3.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KPA46082.1 - 0.079 12.9 3.7 0.12 12.3 1.8 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 KPA46082.1 - 0.096 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.29 KPA46082.1 - 0.64 10.0 3.5 1.4 8.9 3.5 1.6 1 0 0 1 1 1 0 PHD-finger CAP_GLY PF01302.25 KPA46083.1 - 4.1e-20 71.6 1.2 6e-20 71.0 1.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KPA46083.1 - 1.8e-19 69.9 0.0 2.8e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KPA46083.1 - 0.00015 21.4 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family T6_Ig_like PF18002.1 KPA46083.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 T6 antigen Ig like domain Myb_DNA-binding PF00249.31 KPA46084.1 - 3.4e-15 55.9 2.8 7.4e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPA46084.1 - 2.4e-06 27.7 2.7 0.0017 18.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Methyltransf_11 PF08241.12 KPA46085.1 - 1.6e-12 47.9 0.0 3.6e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA46085.1 - 3.1e-11 43.8 0.2 4.9e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA46085.1 - 3.5e-09 36.6 0.0 7.8e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA46085.1 - 3.5e-07 30.2 0.0 6.8e-07 29.3 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA46085.1 - 6.3e-07 30.1 0.0 1.3e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPA46085.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GFO_IDH_MocA PF01408.22 KPA46086.1 - 7.1e-16 59.1 0.1 1.3e-15 58.3 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OpuAC PF04069.12 KPA46086.1 - 0.0048 16.5 0.4 18 4.8 0.0 3.4 4 0 0 4 4 4 3 Substrate binding domain of ABC-type glycine betaine transport system Aldo_ket_red PF00248.21 KPA46087.1 - 3.6e-15 55.9 0.0 6.1e-15 55.2 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family DS PF01916.17 KPA46089.1 - 3.9e-130 433.3 0.0 4.5e-130 433.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Myb_DNA-binding PF00249.31 KPA46090.1 - 5.8e-10 39.2 0.0 2.2e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KPA46090.1 - 0.047 13.6 2.3 0.07 13.0 0.0 2.5 2 0 0 2 2 2 0 Myb DNA-binding like DUF3086 PF11285.8 KPA46090.1 - 0.052 12.7 0.8 0.21 10.6 0.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Myb_DNA-bind_6 PF13921.6 KPA46090.1 - 0.099 12.9 1.5 6.5 7.1 0.1 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain DASH_Dad1 PF08649.10 KPA46091.1 - 4.8e-27 93.9 1.7 6.2e-27 93.5 1.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KPA46091.1 - 0.0062 16.5 0.1 0.0089 16.0 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 CK2S PF15011.6 KPA46091.1 - 0.062 13.2 0.0 0.07 13.0 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate DUF4363 PF14276.6 KPA46092.1 - 0.45 10.7 3.3 0.41 10.8 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) CMV_1a PF12467.8 KPA46092.1 - 9.5 6.5 10.7 24 5.3 0.4 3.1 3 1 0 3 3 3 0 Cucumber mosaic virus 1a protein family RFC1 PF08519.12 KPA46093.1 - 6.1e-56 188.9 0.0 3e-55 186.7 0.0 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KPA46093.1 - 6.1e-14 52.2 0.0 1.5e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KPA46093.1 - 6e-08 33.2 0.0 2.4e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KPA46093.1 - 0.00022 21.1 0.0 0.00048 19.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KPA46093.1 - 0.0021 18.4 0.0 0.01 16.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KPA46093.1 - 0.0028 17.6 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KPA46093.1 - 0.0035 17.8 0.1 0.027 14.9 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KPA46093.1 - 0.015 15.8 0.1 0.11 13.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KPA46093.1 - 0.061 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KPA46093.1 - 0.075 13.2 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KPA46093.1 - 0.41 10.9 0.0 0.41 10.9 0.0 2.2 2 0 0 2 2 1 0 AAA domain Ribosomal_L16 PF00252.18 KPA46094.1 - 3.6e-30 104.7 0.9 5.5e-30 104.1 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol3_delta2 PF13177.6 KPA46095.1 - 2.7e-11 43.5 0.1 5.6e-11 42.5 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KPA46095.1 - 8.6e-07 29.4 0.1 1.8e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPA46095.1 - 3.1e-06 27.5 0.0 3.7e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KPA46095.1 - 0.00037 20.3 0.4 0.0012 18.7 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA46095.1 - 0.00094 19.6 0.4 0.01 16.2 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.11 KPA46095.1 - 0.001 19.4 0.1 0.0037 17.7 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain T4SS-DNA_transf PF02534.14 KPA46095.1 - 0.011 14.6 0.1 0.041 12.7 0.0 1.8 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Rad17 PF03215.15 KPA46095.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 KPA46095.1 - 0.025 15.1 0.0 0.06 13.9 0.0 1.7 2 0 0 2 2 1 0 ABC transporter DNA_pol3_delta PF06144.13 KPA46095.1 - 0.041 13.7 0.1 0.078 12.8 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit TniB PF05621.11 KPA46095.1 - 0.049 13.0 0.1 0.53 9.7 0.1 2.4 1 1 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 KPA46095.1 - 0.1 12.5 0.2 0.35 10.7 0.2 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KPA46095.1 - 0.19 11.7 0.4 0.74 9.8 0.4 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AMP-binding PF00501.28 KPA46096.1 - 1.7e-86 290.5 0.0 2.1e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPA46096.1 - 6e-25 88.0 4.6 5e-24 85.1 1.2 3.1 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KPA46096.1 - 1.8e-16 59.8 0.1 4.6e-16 58.5 0.1 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Reprolysin_5 PF13688.6 KPA46097.1 - 2.9e-60 203.8 2.9 2.9e-60 203.8 2.9 2.5 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KPA46097.1 - 3.7e-51 173.8 1.5 4.6e-51 173.5 0.5 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KPA46097.1 - 3.4e-46 157.5 0.5 7.3e-46 156.4 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KPA46097.1 - 6.1e-17 62.2 35.9 6.1e-17 62.2 35.9 4.8 4 2 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KPA46097.1 - 1.3e-13 51.5 0.0 2.8e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 KPA46097.1 - 0.00062 20.0 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide TMEM100 PF16311.5 KPA46097.1 - 0.025 14.2 1.0 0.067 12.8 1.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 100 WD40 PF00400.32 KPA46099.1 - 5.3e-09 36.6 10.8 0.032 15.1 0.0 7.2 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA46099.1 - 1.5e-07 31.6 0.0 0.0077 16.5 0.0 4.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KPA46099.1 - 0.014 15.3 0.4 0.083 12.9 0.2 2.2 2 0 0 2 2 2 0 LisH Vps16_N PF04841.13 KPA46099.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region IKI3 PF04762.12 KPA46099.1 - 0.033 12.2 0.0 0.064 11.2 0.0 1.4 1 0 0 1 1 1 0 IKI3 family UBA2_C PF16195.5 KPA46099.1 - 0.047 14.4 1.1 0.17 12.6 1.1 2.0 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus SSP160 PF06933.11 KPA46099.1 - 1.5 6.9 5.2 2.5 6.2 5.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1751 PF08551.10 KPA46100.1 - 2.5e-26 92.1 5.6 4.7e-26 91.2 5.6 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KPA46100.1 - 0.019 14.9 10.7 0.034 14.2 10.7 1.3 1 0 0 1 1 1 0 Rhomboid family DUF3377 PF11857.8 KPA46100.1 - 0.2 11.6 0.7 0.57 10.2 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Ferric_reduct PF01794.19 KPA46101.1 - 6e-17 61.9 12.2 6e-17 61.9 12.2 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPA46101.1 - 1.7e-16 60.7 0.0 2.5e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPA46101.1 - 1.4e-07 31.5 0.0 8.6e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KPA46101.1 - 0.0014 19.3 0.1 0.014 16.0 0.1 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain RRM_1 PF00076.22 KPA46102.1 - 1.4e-08 34.4 0.0 3.3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPA46102.1 - 1.2e-05 24.9 0.0 3.3e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.20 KPA46103.1 - 2.1e-13 50.2 0.1 3.5e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 RF-1 domain Pkinase PF00069.25 KPA46104.1 - 1.4e-71 241.0 0.0 1.7e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46104.1 - 2.1e-28 99.3 0.0 2.8e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA46104.1 - 2.7e-07 30.2 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KPA46104.1 - 6.2e-05 22.0 0.1 0.00017 20.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KPA46104.1 - 0.0005 20.1 0.1 0.00075 19.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KPA46104.1 - 0.00083 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Equine_IAV_S2 PF06502.11 KPA46104.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein PAP2_3 PF14378.6 KPA46105.1 - 1.1e-21 77.3 14.4 1.1e-21 77.3 14.4 2.0 1 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KPA46105.1 - 1.8e-11 43.9 3.1 1.8e-11 43.9 3.1 3.0 2 1 1 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 KPA46105.1 - 0.014 15.9 9.9 0.12 12.9 4.1 2.6 2 0 0 2 2 2 0 PAP2 superfamily C-terminal RNA_polI_A34 PF08208.11 KPA46106.1 - 2.3e-39 135.6 15.2 2.3e-39 135.6 15.2 5.6 2 2 2 5 5 5 1 DNA-directed RNA polymerase I subunit RPA34.5 CLP1_P PF16575.5 KPA46107.1 - 3.7e-34 118.2 0.0 5.4e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop TniB PF05621.11 KPA46107.1 - 0.22 10.9 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Fungal_trans PF04082.18 KPA46108.1 - 1.2e-16 60.5 1.4 1.9e-16 59.9 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA46108.1 - 0.00024 21.1 15.2 0.00042 20.4 15.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KPA46110.1 - 9.9e-14 50.9 21.8 2.3e-06 27.7 3.3 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA46110.1 - 2.9e-07 30.8 19.2 0.0046 17.7 0.9 4.0 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KPA46110.1 - 4e-05 23.5 12.1 4.3e-05 23.4 0.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KPA46110.1 - 0.00026 20.7 6.1 0.058 13.2 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain CpXC PF14353.6 KPA46110.1 - 0.00086 19.3 0.1 0.0012 18.8 0.1 1.2 1 0 0 1 1 1 1 CpXC protein LIM PF00412.22 KPA46110.1 - 0.0067 16.6 3.0 0.018 15.2 3.1 1.8 1 1 0 1 1 1 1 LIM domain zf-H2C2_2 PF13465.6 KPA46110.1 - 0.012 16.0 0.4 0.012 16.0 0.4 4.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 KPA46110.1 - 0.031 14.2 0.8 0.084 12.8 0.8 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 KPA46110.1 - 0.048 14.0 4.7 0.16 12.3 4.4 2.1 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KPA46110.1 - 0.057 13.7 4.0 2.7 8.4 0.1 3.5 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KPA46110.1 - 0.31 11.1 7.7 3 7.9 0.2 3.3 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_11 PF16622.5 KPA46110.1 - 0.31 10.8 12.3 0.76 9.6 0.9 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type Lgl_C PF08596.10 KPA46111.1 - 1.4e-121 405.9 0.0 2.3e-121 405.2 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KPA46111.1 - 3.2e-05 24.6 1.7 0.038 14.9 0.1 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA46111.1 - 0.043 14.1 0.1 3.5 8.0 0.0 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA46111.1 - 0.085 11.5 0.3 25 3.4 0.0 3.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KPA46111.1 - 0.33 11.5 3.2 2.3 8.8 0.3 3.8 3 0 0 3 3 3 0 PQQ-like domain MFS_1 PF07690.16 KPA46113.1 - 7.7e-32 110.6 29.3 7.7e-32 110.6 29.3 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KPA46113.1 - 0.00012 21.5 14.2 0.00042 19.7 14.0 1.9 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB Remorin_C PF03763.13 KPA46113.1 - 0.77 9.7 2.9 10 6.0 0.2 2.7 3 0 0 3 3 3 0 Remorin, C-terminal region Sacchrp_dh_C PF16653.5 KPA46114.1 - 5.3e-85 285.7 0.0 7.7e-85 285.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KPA46114.1 - 1.1e-23 83.9 1.3 1.7e-23 83.3 1.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KPA46114.1 - 2.2e-06 27.8 0.4 6.9e-06 26.2 0.4 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KPA46114.1 - 3.9e-06 26.9 1.2 7.2e-06 26.0 1.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 KPA46114.1 - 0.011 16.3 0.4 0.029 14.9 0.4 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KPA46114.1 - 0.023 15.1 0.4 0.076 13.5 0.3 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KPA46114.1 - 0.025 13.9 0.3 0.041 13.2 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 KPA46114.1 - 0.071 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KPA46114.1 - 0.1 12.1 0.6 0.16 11.5 0.6 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_3 PF03447.16 KPA46114.1 - 0.13 13.0 1.4 0.2 12.3 1.4 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Piwi PF02171.17 KPA46116.1 - 1.2e-67 228.3 0.0 8.4e-54 182.9 0.0 2.2 1 1 1 2 2 2 2 Piwi domain ArgoN PF16486.5 KPA46116.1 - 1.9e-16 60.9 0.0 4.4e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KPA46116.1 - 7.7e-13 47.9 0.1 6.9e-12 44.9 0.0 2.4 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 KPA46116.1 - 9.3e-13 48.2 0.0 1.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KPA46116.1 - 2.3e-12 47.0 0.0 4.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KPA46116.1 - 2.7e-06 27.5 0.0 7.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute Suf PF05843.14 KPA46117.1 - 6.1e-88 295.6 0.1 6.1e-88 295.6 0.1 5.3 4 3 1 5 5 5 1 Suppressor of forked protein (Suf) HAT PF02184.16 KPA46117.1 - 0.00098 19.0 0.1 0.4 10.7 0.0 2.9 2 0 0 2 2 2 2 HAT (Half-A-TPR) repeat ASF1_hist_chap PF04729.13 KPA46118.1 - 6.4e-73 243.8 0.0 8.4e-73 243.4 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone SURF2 PF05477.11 KPA46118.1 - 1.7 8.3 7.6 2.1 8.0 7.6 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Na_trans_assoc PF06512.13 KPA46118.1 - 4.9 7.4 12.5 6.3 7.0 12.5 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 KPA46118.1 - 5.1 5.2 19.7 6.5 4.8 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family CorA PF01544.18 KPA46119.1 - 1.7e-16 60.4 0.3 3.4e-16 59.4 0.3 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DivIVA PF05103.13 KPA46119.1 - 0.0017 18.4 1.0 0.065 13.3 1.0 2.2 2 0 0 2 2 2 1 DivIVA protein YabA PF06156.13 KPA46119.1 - 0.097 13.3 0.4 0.19 12.4 0.4 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF484 PF04340.12 KPA46119.1 - 0.17 11.6 0.9 0.75 9.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF484 DivIC PF04977.15 KPA46119.1 - 0.18 11.6 0.5 0.38 10.6 0.5 1.5 1 0 0 1 1 1 0 Septum formation initiator CBFB_NFYA PF02045.15 KPA46120.1 - 1.8e-28 98.9 4.6 3.5e-28 98.0 4.6 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 KPA46120.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein Paf1 PF03985.13 KPA46120.1 - 2.5 7.0 5.8 3.6 6.5 5.8 1.1 1 0 0 1 1 1 0 Paf1 Redoxin PF08534.10 KPA46121.1 - 8e-26 90.5 0.0 9.5e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KPA46121.1 - 1e-06 28.7 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family RasGAP PF00616.19 KPA46122.1 - 3e-58 196.9 2.6 3.3e-58 196.8 0.0 2.3 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KPA46122.1 - 6.6e-30 104.0 7.9 6.6e-30 104.0 7.9 2.7 3 0 0 3 3 3 1 RasGAP C-terminus YabA PF06156.13 KPA46122.1 - 1.9 9.2 9.8 7.2 7.3 1.2 2.9 2 0 0 2 2 2 0 Initiation control protein YabA DUF5344 PF17279.2 KPA46122.1 - 2.2 8.9 6.2 7.9 7.1 1.9 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5344) FlxA PF14282.6 KPA46122.1 - 9.7 6.3 15.4 6 6.9 3.4 3.1 2 1 1 3 3 3 0 FlxA-like protein APH PF01636.23 KPA46123.1 - 8.5e-44 150.3 0.0 3.2e-43 148.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KPA46123.1 - 3.3e-06 26.6 0.0 3.9e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KPA46123.1 - 0.0015 18.2 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KPA46123.1 - 0.02 14.5 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.14 KPA46123.1 - 0.099 11.8 0.0 1 8.5 0.0 2.2 1 1 0 1 1 1 0 Fructosamine kinase Kdo PF06293.14 KPA46123.1 - 0.12 11.8 0.0 0.38 10.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MTS PF05175.14 KPA46124.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain LSM PF01423.22 KPA46125.1 - 2.3e-19 68.9 0.1 2.8e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KPA46125.1 - 0.00074 19.6 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain SelK_SelG PF10961.8 KPA46125.1 - 0.023 15.3 4.1 0.035 14.7 4.1 1.3 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Cullin PF00888.22 KPA46126.1 - 2.3e-201 670.6 5.2 2.9e-201 670.3 5.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KPA46126.1 - 2e-26 91.8 1.5 4.1e-26 90.8 0.3 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain DFF-C PF09033.10 KPA46126.1 - 0.21 11.5 2.5 0.17 11.8 0.4 2.0 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain NTase_sub_bind PF08780.11 KPA46126.1 - 0.3 11.0 3.7 1 9.4 0.1 3.2 3 0 0 3 3 3 0 Nucleotidyltransferase substrate binding protein like LSM PF01423.22 KPA46127.1 - 9.7e-18 63.6 0.5 1.2e-17 63.3 0.5 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KPA46127.1 - 0.0021 18.2 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 KPA46127.1 - 0.0036 16.9 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Hfq protein AEP1 PF17049.5 KPA46127.1 - 0.0053 15.9 0.1 0.0053 15.9 0.1 1.1 1 0 0 1 1 1 1 ATPase expression protein 1 DRMBL PF07522.14 KPA46128.1 - 3.5e-32 110.9 0.0 6.8e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KPA46128.1 - 6.1e-08 32.4 0.1 2e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain TRAPP PF04051.16 KPA46129.1 - 0.15 11.8 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component Pkinase PF00069.25 KPA46130.1 - 1.2e-54 185.4 0.0 1.6e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46130.1 - 1.8e-40 138.9 0.0 2.6e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPA46130.1 - 0.00043 19.3 0.1 0.046 12.7 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 KPA46130.1 - 0.0015 17.9 0.0 0.0065 15.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KPA46130.1 - 0.0061 15.4 0.1 0.021 13.6 0.0 1.8 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 KPA46130.1 - 0.033 14.1 0.0 0.3 11.0 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KPA46130.1 - 0.058 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Telomere_reg-2 PF10193.9 KPA46131.1 - 2.4e-34 118.0 0.0 1.6e-33 115.4 0.0 2.4 2 0 0 2 2 2 1 Telomere length regulation protein ThiF PF00899.21 KPA46132.1 - 4.4e-67 226.0 0.0 6.2e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KPA46132.1 - 4.6e-32 110.0 0.1 7.4e-32 109.3 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KPA46132.1 - 1.9e-05 24.7 1.1 0.00041 20.4 0.0 2.5 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 KPA46132.1 - 9.6e-05 22.9 0.0 0.00039 21.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Sacchrp_dh_NADP PF03435.18 KPA46132.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 KPA46132.1 - 0.045 14.3 0.1 0.34 11.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KPA46132.1 - 0.049 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KPA46132.1 - 0.056 13.4 2.0 0.75 9.8 0.0 2.8 2 2 1 3 3 3 0 FAD-NAD(P)-binding E1_UFD PF09358.10 KPA46132.1 - 0.097 13.4 0.0 0.38 11.5 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin fold domain UBA_e1_thiolCys PF10585.9 KPA46132.1 - 0.21 11.5 1.0 8.2 6.3 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site RNA_pol_A_bac PF01000.26 KPA46133.1 - 5.3e-25 88.0 0.0 1.3e-24 86.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KPA46133.1 - 6.2e-21 73.6 0.0 9.6e-21 73.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Nucleoporin_FG PF13634.6 KPA46134.1 - 4.7e-10 40.2 43.5 8.1e-07 29.8 12.3 7.1 3 2 2 5 5 5 3 Nucleoporin FG repeat region NUP214 PF16755.5 KPA46134.1 - 1.4e-06 27.8 0.0 8.6e-06 25.2 0.0 2.0 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 KPA46134.1 - 0.00021 21.5 0.0 0.0071 16.6 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Na_trans_assoc PF06512.13 KPA46134.1 - 0.0076 16.6 2.2 0.022 15.1 2.2 1.7 1 0 0 1 1 1 1 Sodium ion transport-associated DUF1796 PF08795.10 KPA46134.1 - 0.037 14.0 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) FapA PF03961.13 KPA46134.1 - 0.082 11.5 0.5 0.13 10.9 0.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A SDA1 PF05285.12 KPA46134.1 - 1.3 8.4 10.4 0.024 14.1 2.0 2.0 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 KPA46134.1 - 2.1 6.5 5.6 3.6 5.8 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Proteasome PF00227.26 KPA46135.1 - 6.2e-48 162.8 0.0 8.1e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KPA46135.1 - 1.8e-13 49.6 0.7 1.8e-13 49.6 0.7 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Sel1 PF08238.12 KPA46136.1 - 1.1e-10 41.9 8.6 0.0079 16.8 0.4 3.8 4 0 0 4 4 4 3 Sel1 repeat COPIIcoated_ERV PF07970.12 KPA46137.1 - 2.4e-86 289.1 0.2 4.8e-86 288.2 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KPA46137.1 - 1.1e-30 105.8 0.0 3.9e-30 104.0 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CSTF2_hinge PF14327.6 KPA46138.1 - 2.5e-32 111.2 1.6 2.5e-32 111.2 1.6 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KPA46138.1 - 1.4e-21 76.0 0.0 2.3e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KPA46138.1 - 1.2e-10 40.8 5.7 1.2e-10 40.8 5.7 3.2 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KPA46138.1 - 0.014 15.5 0.0 0.035 14.2 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 KPA46138.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 KPA46138.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 CorA PF01544.18 KPA46139.1 - 1.3e-40 139.6 0.3 4.6e-40 137.8 0.3 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DctQ PF04290.12 KPA46139.1 - 0.1 12.5 0.4 0.17 11.8 0.4 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component CBF PF03914.17 KPA46140.1 - 3.4e-36 124.8 0.1 1e-35 123.3 0.0 1.9 1 1 1 2 2 2 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.14 KPA46141.1 - 2.2e-51 173.7 9.1 2.8e-51 173.4 9.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.11 KPA46141.1 - 0.085 12.9 1.8 0.11 12.6 0.7 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) tRNA_anti-codon PF01336.25 KPA46141.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MSC PF09402.10 KPA46142.1 - 8.3e-116 387.1 0.0 1.2e-115 386.6 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KPA46142.1 - 4.1e-16 58.4 0.1 8e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 KPA46142.1 - 0.0029 17.2 0.0 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 Thymopoietin protein RRF PF01765.19 KPA46142.1 - 0.4 10.6 3.2 8.8 6.3 0.3 2.4 2 0 0 2 2 2 0 Ribosome recycling factor PAXIP1_C PF15364.6 KPA46142.1 - 0.86 9.9 14.1 0.09 13.1 8.8 2.0 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein FAD_binding_3 PF01494.19 KPA46143.1 - 8.2e-26 91.1 0.0 1.7e-24 86.7 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPA46143.1 - 1.7e-05 24.6 0.2 0.057 13.0 0.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA46143.1 - 5.7e-05 22.5 0.0 0.00066 19.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPA46143.1 - 0.00011 21.4 0.3 0.0067 15.5 0.1 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.10 KPA46143.1 - 0.00011 21.3 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 KPA46143.1 - 0.0093 15.2 0.0 0.059 12.6 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KPA46143.1 - 0.0099 16.1 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPA46143.1 - 0.018 13.8 0.0 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KPA46143.1 - 0.078 13.0 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 KPA46143.1 - 0.081 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KPA46143.1 - 0.11 11.3 0.2 3.7 6.3 0.1 2.6 2 1 0 3 3 3 0 Tryptophan halogenase Complex1_49kDa PF00346.19 KPA46144.1 - 2.1e-123 410.8 0.0 2.8e-123 410.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KPA46144.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Acetyltransf_3 PF13302.7 KPA46145.1 - 3e-24 86.3 0.0 3.6e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA46145.1 - 7.1e-06 26.3 0.0 1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KPA46145.1 - 8.5e-06 26.0 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 KPA46146.1 - 5.6e-08 32.8 10.9 8.3e-08 32.2 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAN_1 PF00024.26 KPA46147.1 - 5.4e-05 23.1 0.1 9.5e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 KPA46147.1 - 0.00022 20.7 0.1 0.0014 18.1 0.1 2.0 1 1 0 1 1 1 1 Fringe-like UCH PF00443.29 KPA46148.1 - 2.4e-38 132.1 0.0 1.1e-32 113.6 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPA46148.1 - 3.6e-08 33.4 4.5 0.00022 20.9 1.3 3.0 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase ATG11 PF10377.9 KPA46150.1 - 5.6e-45 152.5 0.4 5.6e-45 152.5 0.4 3.8 3 0 0 3 3 3 1 Autophagy-related protein 11 MscS_porin PF12795.7 KPA46150.1 - 8.1e-06 25.6 15.5 8.1e-06 25.6 15.5 5.0 2 1 2 4 4 4 1 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 KPA46150.1 - 7.2e-05 22.8 16.4 7.2e-05 22.8 16.4 8.3 6 3 3 9 9 9 3 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 KPA46150.1 - 0.00052 19.8 8.8 0.00052 19.8 8.8 6.6 6 2 3 9 9 9 1 Domain of unknown function (DUF4201) Tropomyosin PF00261.20 KPA46150.1 - 0.0011 18.4 7.2 0.0011 18.4 7.2 7.3 3 1 3 6 6 6 1 Tropomyosin Spc7 PF08317.11 KPA46150.1 - 0.0015 17.5 17.1 0.0015 17.5 17.1 7.3 4 3 4 8 8 8 3 Spc7 kinetochore protein APG17 PF04108.12 KPA46150.1 - 0.0033 16.6 11.4 0.0033 16.6 11.4 6.1 2 2 1 4 4 4 1 Autophagy protein Apg17 Cleaved_Adhesin PF07675.11 KPA46150.1 - 0.0046 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Cleaved Adhesin Domain FERM_f0 PF16511.5 KPA46150.1 - 0.0056 17.0 0.1 1.7 9.0 0.0 2.8 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM NuA4 PF09340.10 KPA46150.1 - 0.11 12.4 8.8 5 7.1 0.0 4.8 3 2 1 4 4 4 0 Histone acetyltransferase subunit NuA4 CENP-H PF05837.12 KPA46151.1 - 1.3e-35 122.1 9.5 8.1e-34 116.4 2.8 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) TMCO5 PF14992.6 KPA46151.1 - 0.077 12.6 6.4 0.2 11.2 6.4 1.6 1 1 0 1 1 1 0 TMCO5 family HMG_box PF00505.19 KPA46152.1 - 2.7e-24 85.4 1.2 4.2e-24 84.8 1.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KPA46152.1 - 4.5e-18 65.6 1.7 6.8e-18 65.0 1.7 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KPA46152.1 - 0.0034 17.9 0.0 0.0034 17.9 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 KPA46152.1 - 0.027 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain HMG_box_5 PF14887.6 KPA46152.1 - 0.045 13.7 0.8 0.045 13.7 0.8 1.8 2 1 0 2 2 2 0 HMG (high mobility group) box 5 PGM_PMM_I PF02878.16 KPA46154.1 - 1.3e-33 115.6 0.1 2.1e-33 115.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KPA46154.1 - 2.2e-26 92.3 0.0 3.5e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KPA46154.1 - 4.8e-16 59.2 0.0 1.1e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KPA46154.1 - 2.8e-05 24.2 0.0 6.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.24 KPA46155.1 - 9.1e-25 88.1 0.2 1.1e-24 87.9 0.2 1.1 1 0 0 1 1 1 1 Exonuclease GFO_IDH_MocA PF01408.22 KPA46156.1 - 4.2e-09 37.3 0.0 1.5e-08 35.5 0.0 1.9 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPA46156.1 - 0.0001 22.3 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Alpha_GJ PF03229.13 KPA46157.1 - 0.11 13.0 11.2 0.092 13.3 8.8 2.1 1 1 1 2 2 2 0 Alphavirus glycoprotein J SKG6 PF08693.10 KPA46157.1 - 6.8 6.2 7.7 3.5 7.1 5.2 1.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain NUDIX PF00293.28 KPA46158.1 - 0.0002 21.4 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Ribosomal_S19 PF00203.21 KPA46160.1 - 4.5e-33 113.0 0.2 6.1e-33 112.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 KPA46160.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH EpmC PF04315.12 KPA46160.1 - 0.15 11.7 0.0 9.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Elongation factor P hydroxylase GAS PF13851.6 KPA46161.1 - 2.9e-07 30.0 6.2 5.7e-07 29.1 6.2 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KPA46161.1 - 4.6e-05 23.7 1.8 8.1e-05 22.9 1.8 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KPA46161.1 - 0.00038 21.0 12.5 0.00056 20.4 12.5 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Cluap1 PF10234.9 KPA46161.1 - 0.00078 18.9 0.4 0.0011 18.5 0.4 1.3 1 0 0 1 1 1 1 Clusterin-associated protein-1 CEP63 PF17045.5 KPA46161.1 - 0.0011 18.9 6.8 0.0017 18.3 6.8 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa HMMR_C PF15908.5 KPA46161.1 - 0.0012 19.1 3.6 0.0025 18.1 3.0 1.7 1 1 1 2 2 1 1 Hyaluronan mediated motility receptor C-terminal FlaC_arch PF05377.11 KPA46161.1 - 0.002 18.5 1.4 0.23 11.9 0.5 2.8 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) FPP PF05911.11 KPA46161.1 - 0.0025 16.1 0.7 0.0033 15.7 0.7 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 KPA46161.1 - 0.004 16.1 7.0 0.0073 15.2 7.0 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein KASH_CCD PF14662.6 KPA46161.1 - 0.0048 16.8 7.6 0.0097 15.8 7.6 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 KPA46161.1 - 0.0053 16.8 4.2 0.84 9.7 2.0 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Cast PF10174.9 KPA46161.1 - 0.0065 14.8 6.4 0.0088 14.3 6.4 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone SKA1 PF07160.12 KPA46161.1 - 0.014 15.3 0.9 0.025 14.4 0.9 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 KfrA_N PF11740.8 KPA46161.1 - 0.019 15.6 1.8 0.04 14.6 0.2 2.2 2 0 0 2 2 1 0 Plasmid replication region DNA-binding N-term DUF2353 PF09789.9 KPA46161.1 - 0.021 14.2 8.9 0.035 13.5 8.9 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF848 PF05852.11 KPA46161.1 - 0.023 14.8 5.8 0.039 14.0 5.3 1.6 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) RasGAP_C PF03836.15 KPA46161.1 - 0.024 14.8 3.2 0.053 13.7 3.2 1.6 1 1 0 1 1 1 0 RasGAP C-terminus HOOK PF05622.12 KPA46161.1 - 0.026 12.7 8.4 0.034 12.3 8.4 1.1 1 0 0 1 1 1 0 HOOK protein CAP_N PF01213.19 KPA46161.1 - 0.03 13.8 3.4 0.027 14.0 1.5 1.8 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal bZIP_1 PF00170.21 KPA46161.1 - 0.033 14.3 1.8 0.063 13.4 0.9 1.9 1 1 0 1 1 1 0 bZIP transcription factor Uso1_p115_C PF04871.13 KPA46161.1 - 0.034 14.5 8.6 0.087 13.2 3.1 2.5 2 1 1 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region EzrA PF06160.12 KPA46161.1 - 0.038 12.2 5.1 0.053 11.7 5.1 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA YscO PF07321.12 KPA46161.1 - 0.038 14.0 5.6 0.076 13.0 5.6 1.6 1 0 0 1 1 1 0 Type III secretion protein YscO BLOC1_2 PF10046.9 KPA46161.1 - 0.038 14.3 3.5 3.5 8.0 0.1 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Golgin_A5 PF09787.9 KPA46161.1 - 0.039 13.4 6.4 0.059 12.8 6.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 NPV_P10 PF05531.12 KPA46161.1 - 0.039 14.4 9.2 0.071 13.6 2.9 3.3 2 1 2 4 4 3 0 Nucleopolyhedrovirus P10 protein FapA PF03961.13 KPA46161.1 - 0.047 12.3 1.6 0.065 11.8 1.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4618 PF15397.6 KPA46161.1 - 0.049 13.1 5.1 0.069 12.6 3.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Macoilin PF09726.9 KPA46161.1 - 0.05 12.2 0.9 0.064 11.8 0.9 1.1 1 0 0 1 1 1 0 Macoilin family TBCC_N PF16752.5 KPA46161.1 - 0.062 13.7 3.3 0.15 12.5 3.3 1.7 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Csm1_N PF18504.1 KPA46161.1 - 0.077 13.3 6.8 1.9 8.9 3.2 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain Tropomyosin_1 PF12718.7 KPA46161.1 - 0.077 13.1 9.8 0.14 12.4 9.8 1.3 1 0 0 1 1 1 0 Tropomyosin like Cep57_CLD_2 PF14197.6 KPA46161.1 - 0.085 13.0 13.1 0.4 10.8 7.8 3.3 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Fez1 PF06818.15 KPA46161.1 - 0.09 13.2 6.8 0.15 12.5 6.8 1.3 1 0 0 1 1 1 0 Fez1 Cnn_1N PF07989.11 KPA46161.1 - 0.091 12.9 7.1 0.21 11.8 1.2 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 KPA46161.1 - 0.11 12.5 9.5 0.27 11.2 9.5 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 KPA46161.1 - 0.13 13.2 4.9 0.26 12.2 4.4 1.7 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Seryl_tRNA_N PF02403.22 KPA46161.1 - 0.13 12.5 8.3 0.23 11.7 5.8 2.5 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_Maf PF03131.17 KPA46161.1 - 0.14 12.7 6.2 0.11 13.0 3.3 2.3 3 0 0 3 3 1 0 bZIP Maf transcription factor Fungal_TACC PF12709.7 KPA46161.1 - 0.15 12.5 3.5 0.18 12.3 1.3 2.1 1 1 0 2 2 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins SPAM PF02090.15 KPA46161.1 - 0.15 11.9 6.0 0.38 10.6 6.1 1.5 1 1 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF2730 PF10805.8 KPA46161.1 - 0.15 12.1 3.5 0.67 10.1 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Syntaxin-6_N PF09177.11 KPA46161.1 - 0.16 12.6 8.7 4.9 7.8 3.7 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TMF_TATA_bd PF12325.8 KPA46161.1 - 0.17 12.1 6.8 0.33 11.2 6.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 KPA46161.1 - 0.19 11.8 11.1 0.38 10.8 10.9 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4201 PF13870.6 KPA46161.1 - 0.22 11.3 7.8 0.37 10.5 3.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) bZIP_2 PF07716.15 KPA46161.1 - 0.22 11.6 4.9 0.14 12.3 2.3 2.1 2 0 0 2 2 1 0 Basic region leucine zipper Laminin_II PF06009.12 KPA46161.1 - 0.22 11.5 2.7 0.68 10.0 2.4 1.9 1 1 0 1 1 1 0 Laminin Domain II Rootletin PF15035.6 KPA46161.1 - 0.23 11.4 7.4 0.72 9.9 7.6 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Snapin_Pallidin PF14712.6 KPA46161.1 - 0.24 11.8 6.2 1.1 9.7 4.8 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Prefoldin PF02996.17 KPA46161.1 - 0.26 11.2 3.4 1.4 8.9 1.7 2.4 2 0 0 2 2 2 0 Prefoldin subunit Atg14 PF10186.9 KPA46161.1 - 0.27 10.3 7.1 0.42 9.7 7.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Retrotrans_gag PF03732.17 KPA46161.1 - 0.29 11.4 3.8 7.8 6.9 3.8 2.9 1 1 0 1 1 1 0 Retrotransposon gag protein YabA PF06156.13 KPA46161.1 - 0.33 11.6 4.1 0.73 10.5 3.8 1.8 1 1 0 1 1 1 0 Initiation control protein YabA Allexi_40kDa PF05549.11 KPA46161.1 - 0.41 10.1 2.5 1.3 8.5 2.4 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein TolA_bind_tri PF16331.5 KPA46161.1 - 0.45 10.6 13.3 4.5 7.4 4.5 2.9 1 1 1 2 2 2 0 TolA binding protein trimerisation CC2-LZ PF16516.5 KPA46161.1 - 0.55 10.6 6.9 0.99 9.8 5.7 2.0 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Mto2_bdg PF12808.7 KPA46161.1 - 0.62 10.4 6.3 0.67 10.3 2.6 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Occludin_ELL PF07303.13 KPA46161.1 - 0.67 10.7 3.0 2 9.2 1.1 2.2 1 1 0 2 2 2 0 Occludin homology domain ADIP PF11559.8 KPA46161.1 - 0.7 10.0 7.4 1.2 9.2 6.7 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding THOC7 PF05615.13 KPA46161.1 - 0.74 10.1 7.1 1.6 9.0 4.7 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 DUF4407 PF14362.6 KPA46161.1 - 0.74 9.1 6.9 4.3 6.6 6.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KPA46161.1 - 1 9.8 7.5 1.2 9.7 4.5 2.6 2 1 0 2 2 1 0 Cell division protein ZapB DivIC PF04977.15 KPA46161.1 - 1 9.2 6.7 10 6.0 4.8 2.8 2 1 0 2 2 2 0 Septum formation initiator Spc24 PF08286.11 KPA46161.1 - 1.4 9.2 6.6 11 6.3 3.1 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF1640 PF07798.11 KPA46161.1 - 1.6 8.8 7.7 4.6 7.2 7.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF2968 PF11180.8 KPA46161.1 - 1.6 8.3 8.9 1.9 8.1 6.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Rx_N PF18052.1 KPA46161.1 - 2.7 8.4 11.3 1.4 9.2 1.1 3.1 2 1 1 3 3 3 0 Rx N-terminal domain BST2 PF16716.5 KPA46161.1 - 3.9 8.1 6.8 60 4.3 7.1 2.2 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 Sec2p PF06428.11 KPA46161.1 - 4.1 7.4 10.0 15 5.6 6.4 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p HalX PF08663.10 KPA46161.1 - 5.9 7.3 10.9 15 6.0 2.7 2.9 2 0 0 2 2 2 0 HalX domain DUF4140 PF13600.6 KPA46161.1 - 8.2 6.9 11.0 21 5.6 4.1 2.9 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) AA_permease_2 PF13520.6 KPA46162.1 - 5.7e-58 196.7 47.0 7.1e-58 196.4 47.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPA46162.1 - 8.5e-20 70.8 37.5 1.1e-19 70.4 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4690 PF15756.5 KPA46163.1 - 0.026 15.1 0.1 0.039 14.5 0.1 1.2 1 0 0 1 1 1 0 Small Novel Rich in Cartilage EutA PF06277.11 KPA46163.1 - 0.2 10.4 0.6 0.27 10.0 0.6 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA CYYR1 PF10873.8 KPA46163.1 - 2.8 8.4 5.6 0.75 10.2 2.4 1.7 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 GATase PF00117.28 KPA46164.1 - 3.4e-13 49.8 0.0 4.7e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KPA46164.1 - 0.0013 18.6 0.1 0.029 14.1 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 KPA46164.1 - 0.033 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 KPA46164.1 - 0.11 12.3 0.0 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 SNO glutamine amidotransferase family Fungal_trans_2 PF11951.8 KPA46165.1 - 1.5e-42 145.8 2.6 3e-42 144.8 2.6 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA46165.1 - 5e-08 32.9 11.5 8.3e-08 32.2 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAZAP2 PF11029.8 KPA46165.1 - 4.8 8.1 9.4 0.38 11.7 1.5 2.7 2 1 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) SHMT PF00464.19 KPA46166.1 - 3.6e-202 671.3 0.0 4.2e-202 671.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KPA46166.1 - 0.00031 20.0 0.0 0.0011 18.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KPA46166.1 - 0.033 13.5 0.1 0.068 12.5 0.1 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family GCV_H PF01597.19 KPA46167.1 - 2.9e-38 130.5 1.0 3.5e-38 130.2 1.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KPA46167.1 - 0.008 16.0 0.2 0.015 15.1 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 KPA46167.1 - 0.034 14.1 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GDC-P PF02347.16 KPA46168.1 - 1.3e-184 614.0 0.0 1.6e-169 564.3 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KPA46168.1 - 1.2e-05 24.7 0.1 2.5e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KPA46168.1 - 4.1e-05 22.7 0.2 0.00022 20.3 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class-V RTC4 PF14474.6 KPA46168.1 - 0.063 13.4 0.2 14 5.8 0.0 2.3 2 0 0 2 2 2 0 RTC4-like domain E1-N PF14463.6 KPA46168.1 - 0.087 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 E1 N-terminal domain Aminotran_1_2 PF00155.21 KPA46168.1 - 0.12 11.5 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II Pkinase PF00069.25 KPA46169.1 - 1.7e-07 30.9 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KPA46169.1 - 0.00026 21.0 0.1 0.00027 20.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPA46169.1 - 0.00051 19.7 0.1 0.00092 18.9 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 KPA46169.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KPA46169.1 - 0.063 12.0 0.1 0.089 11.6 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase PABP PF00658.18 KPA46169.1 - 0.083 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain Phage_Arf PF17585.2 KPA46170.1 - 0.37 10.8 1.9 0.95 9.5 0.1 2.4 2 0 0 2 2 2 0 Accessory recombination function protein Pex24p PF06398.11 KPA46172.1 - 7.6e-93 311.4 0.7 1e-92 311.0 0.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4834 PF16118.5 KPA46172.1 - 1.2 10.2 0.0 1.2 10.2 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) SpoIIIAH PF12685.7 KPA46172.1 - 4.9 6.9 10.6 3.5 7.4 0.4 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein HRG PF16954.5 KPA46173.1 - 0.0018 18.7 0.8 0.059 13.8 0.2 2.5 2 0 0 2 2 2 2 Haem-transporter, endosomal/lysosomal, haem-responsive gene Ank_2 PF12796.7 KPA46174.1 - 2.5e-45 153.0 7.2 6.6e-16 58.7 0.1 5.6 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA46174.1 - 2.3e-37 126.9 3.9 1.9e-08 34.7 0.0 7.1 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA46174.1 - 6.7e-30 99.8 0.3 0.00029 21.0 0.1 9.3 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KPA46174.1 - 2.3e-29 101.0 4.4 2.8e-07 30.7 0.1 6.5 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KPA46174.1 - 3.7e-28 96.7 13.7 3.1e-05 24.2 0.1 9.3 9 0 0 9 9 9 8 Ankyrin repeat NACHT PF05729.12 KPA46174.1 - 3.4e-05 23.8 0.0 9.7e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPA46174.1 - 0.0013 19.1 0.0 0.0038 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPA46174.1 - 0.037 14.3 0.0 0.094 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPA46174.1 - 0.069 13.6 0.1 0.29 11.5 0.1 2.1 1 0 0 1 1 1 0 RNA helicase Acetyltransf_10 PF13673.7 KPA46175.1 - 6.3e-06 26.1 0.0 2.2e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA46175.1 - 2.7e-05 24.4 0.0 3.9e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPA46175.1 - 0.0003 21.2 0.0 0.00051 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPA46175.1 - 0.003 17.6 0.0 0.0085 16.2 0.0 1.7 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KPA46175.1 - 0.0097 16.0 0.0 4.5 7.3 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPA46175.1 - 0.05 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein HgmA PF04209.13 KPA46176.1 - 1.8e-192 639.8 0.1 2.1e-192 639.5 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Med9 PF07544.13 KPA46179.1 - 0.00075 19.5 8.9 0.062 13.4 2.3 3.0 1 1 2 3 3 3 2 RNA polymerase II transcription mediator complex subunit 9 TMPIT PF07851.13 KPA46179.1 - 0.00091 18.6 2.1 0.0012 18.1 2.1 1.2 1 0 0 1 1 1 1 TMPIT-like protein KASH_CCD PF14662.6 KPA46179.1 - 0.0011 18.8 7.1 0.0019 18.0 7.1 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH CtIP_N PF10482.9 KPA46179.1 - 0.0017 18.4 6.9 0.0017 18.4 0.4 2.4 1 1 1 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain DUF3450 PF11932.8 KPA46179.1 - 0.0022 17.4 5.7 0.0022 17.4 5.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) TSC22 PF01166.18 KPA46179.1 - 0.0033 17.7 4.4 0.041 14.2 0.1 3.0 2 2 0 2 2 2 1 TSC-22/dip/bun family ABC_tran_CTD PF16326.5 KPA46179.1 - 0.0061 16.8 2.2 0.0061 16.8 2.2 3.5 3 1 1 4 4 4 1 ABC transporter C-terminal domain Csm1_N PF18504.1 KPA46179.1 - 0.0076 16.6 9.3 0.28 11.5 0.1 3.6 3 1 1 4 4 4 1 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 KPA46179.1 - 0.0083 16.1 13.4 0.024 14.6 0.7 3.1 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 KPA46179.1 - 0.01 16.3 6.4 0.01 16.3 6.4 2.8 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF3584 PF12128.8 KPA46179.1 - 0.013 13.0 8.9 0.18 9.3 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 KPA46179.1 - 0.014 15.5 5.0 0.014 15.5 5.0 2.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 KPA46179.1 - 0.019 14.5 9.2 0.012 15.2 6.8 1.7 1 1 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 KPA46179.1 - 0.028 13.3 9.9 0.07 12.0 8.9 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 KPA46179.1 - 0.034 14.8 4.9 0.66 10.6 0.3 3.1 1 1 1 2 2 2 0 SlyX CALCOCO1 PF07888.11 KPA46179.1 - 0.041 12.8 6.3 0.045 12.6 6.3 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 KPA46179.1 - 0.057 13.5 7.4 0.27 11.2 7.6 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Hsk3 PF08227.11 KPA46179.1 - 0.068 13.5 3.1 2.5 8.5 0.4 3.2 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like DUF4559 PF15112.6 KPA46179.1 - 0.079 12.6 7.3 0.072 12.8 5.9 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4559) GNVR PF13807.6 KPA46179.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase DUF3251 PF11622.8 KPA46179.1 - 0.098 12.3 0.6 0.15 11.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) ATG16 PF08614.11 KPA46179.1 - 0.11 12.7 10.9 0.06 13.6 3.9 2.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KPA46179.1 - 0.11 11.8 10.1 0.24 10.7 10.1 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 KPA46179.1 - 0.13 10.9 6.3 0.15 10.7 6.3 1.2 1 0 0 1 1 1 0 AAA domain DUF2203 PF09969.9 KPA46179.1 - 0.14 12.9 6.3 0.13 13.0 3.2 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Lebercilin PF15619.6 KPA46179.1 - 0.17 11.5 9.9 0.43 10.2 9.9 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.6 KPA46179.1 - 0.18 11.5 7.0 0.28 10.9 5.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) ADIP PF11559.8 KPA46179.1 - 0.23 11.5 10.4 1.1 9.3 1.2 2.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4349 PF14257.6 KPA46179.1 - 0.36 10.3 2.9 10 5.5 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) AATF-Che1 PF13339.6 KPA46179.1 - 0.36 11.5 5.3 0.44 11.2 2.1 2.3 1 1 0 2 2 2 0 Apoptosis antagonizing transcription factor JIP_LZII PF16471.5 KPA46179.1 - 0.36 11.0 4.7 6.1 7.1 1.6 3.4 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Tropomyosin_1 PF12718.7 KPA46179.1 - 0.41 10.8 13.8 6.4 6.9 7.8 2.9 2 1 1 3 3 3 0 Tropomyosin like FlxA PF14282.6 KPA46179.1 - 0.41 10.7 9.7 0.18 11.8 1.5 2.7 1 1 1 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 KPA46179.1 - 0.68 10.1 7.0 3.3 7.9 0.8 2.8 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family MCC-bdg_PDZ PF10506.9 KPA46179.1 - 0.75 9.9 5.5 3.7 7.6 0.3 3.7 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome BLOC1_2 PF10046.9 KPA46179.1 - 0.99 9.7 10.7 3.8 7.9 0.7 3.3 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 KPA46179.1 - 1 9.2 12.1 3.1 7.6 0.3 3.4 1 1 2 3 3 3 0 Septum formation initiator ZapB PF06005.12 KPA46179.1 - 1.5 9.3 13.7 2.2 8.8 0.4 2.6 2 1 0 3 3 2 0 Cell division protein ZapB DUF4407 PF14362.6 KPA46179.1 - 1.7 7.9 9.6 2.4 7.4 8.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 KPA46179.1 - 2.1 8.1 6.6 4.9 6.9 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) KxDL PF10241.9 KPA46179.1 - 2.2 8.6 8.0 6.6 7.1 2.1 3.3 1 1 1 3 3 3 0 Uncharacterized conserved protein Cep57_MT_bd PF06657.13 KPA46179.1 - 3.8 8.0 6.3 7.1 7.2 0.2 3.5 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF2046 PF09755.9 KPA46180.1 - 0.00066 19.0 0.6 0.035 13.3 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Phage_lysis PF03245.13 KPA46180.1 - 0.018 15.2 1.2 0.043 14.0 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Pox_A_type_inc PF04508.12 KPA46180.1 - 0.032 14.1 0.9 0.094 12.6 0.9 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat PRKG1_interact PF15898.5 KPA46180.1 - 0.04 14.8 0.5 0.04 14.8 0.5 2.5 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Cnn_1N PF07989.11 KPA46180.1 - 0.056 13.6 1.3 0.25 11.5 0.1 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Spc29 PF17082.5 KPA46180.1 - 0.12 12.1 0.3 0.12 12.1 0.3 2.2 2 0 0 2 2 2 0 Spindle Pole Component 29 NUDE_C PF04880.13 KPA46180.1 - 0.24 11.9 0.2 0.24 11.9 0.2 3.0 3 0 0 3 3 3 0 NUDE protein, C-terminal conserved region 5-FTHF_cyc-lig PF01812.20 KPA46180.1 - 0.35 10.7 3.2 0.16 11.8 0.3 1.8 2 0 0 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family ZapB PF06005.12 KPA46180.1 - 1.5 9.4 7.7 0.31 11.5 2.5 2.1 2 0 0 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 KPA46180.1 - 3.3 8.1 6.8 0.7 10.3 1.6 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) RRM_1 PF00076.22 KPA46181.1 - 3.7e-07 29.9 0.1 6.3e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPA46181.1 - 0.026 14.4 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KPA46181.1 - 0.034 14.2 0.1 0.071 13.2 0.1 1.5 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.6 KPA46181.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DZR PF12773.7 KPA46183.1 - 0.36 10.9 6.4 0.43 10.7 1.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon F-box PF00646.33 KPA46184.1 - 1.9e-09 37.1 0.0 0.0014 18.5 0.0 2.6 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 KPA46184.1 - 3.1e-09 36.6 0.0 0.00069 19.5 0.0 2.4 2 0 0 2 2 2 2 F-box-like F-box_4 PF15966.5 KPA46184.1 - 0.056 13.3 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 F-box Xol-1_GHMP-like PF09109.10 KPA46185.1 - 0.21 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like Epimerase PF01370.21 KPA46187.1 - 2.5e-18 66.4 0.0 4.1e-18 65.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPA46187.1 - 1.1e-11 44.3 0.0 1.8e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPA46187.1 - 6.4e-10 38.6 0.0 6.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KPA46187.1 - 4.2e-09 36.3 0.0 7.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KPA46187.1 - 1.3e-08 34.7 0.1 3.2e-06 26.9 0.2 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KPA46187.1 - 8.9e-05 22.5 0.6 0.00025 21.0 0.4 1.8 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 KPA46187.1 - 0.003 17.1 0.3 0.039 13.4 0.4 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPA46187.1 - 0.009 15.9 0.7 0.031 14.2 0.7 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPA46187.1 - 0.016 14.3 0.6 0.037 13.2 0.6 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Rad4 PF03835.15 KPA46188.1 - 1.3e-30 106.0 0.5 3.1e-30 104.8 0.5 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KPA46188.1 - 5.3e-27 94.0 0.1 1.6e-26 92.5 0.1 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KPA46188.1 - 3.3e-23 81.3 0.0 8.3e-23 80.0 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KPA46188.1 - 5e-20 72.2 1.4 5e-20 72.2 1.4 4.0 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KPA46188.1 - 0.01 16.3 0.2 0.056 13.9 0.2 2.3 1 1 0 1 1 1 0 Transglutaminase-like superfamily ABC_tran PF00005.27 KPA46189.1 - 1.7e-48 164.6 0.2 1.8e-26 93.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KPA46189.1 - 4.6e-32 111.5 39.8 4.6e-18 65.4 24.7 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KPA46189.1 - 8.4e-22 78.3 2.1 6.8e-05 22.8 0.0 4.6 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPA46189.1 - 1.4e-11 43.9 2.7 0.00051 19.7 1.0 3.6 3 0 0 3 3 3 3 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KPA46189.1 - 1.2e-06 28.5 0.3 0.0073 16.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 KPA46189.1 - 2.1e-06 27.3 8.7 0.098 12.1 0.4 4.6 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPA46189.1 - 2.4e-06 28.2 4.0 0.026 15.0 0.4 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KPA46189.1 - 0.00011 22.7 0.1 0.59 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KPA46189.1 - 0.00034 20.4 0.0 0.11 12.2 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain DUF4162 PF13732.6 KPA46189.1 - 0.00068 20.3 0.0 0.31 11.8 0.0 3.3 2 1 1 3 3 2 1 Domain of unknown function (DUF4162) AAA_24 PF13479.6 KPA46189.1 - 0.00089 19.0 0.2 16 5.1 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_27 PF13514.6 KPA46189.1 - 0.0059 16.2 0.3 1.6 8.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPA46189.1 - 0.0062 16.3 0.3 4.4 7.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPA46189.1 - 0.0097 16.5 0.0 6 7.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KPA46189.1 - 0.01 15.4 0.6 19 4.8 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KPA46189.1 - 0.011 16.0 0.0 6.6 7.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KPA46189.1 - 0.06 13.1 0.0 44 3.7 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_28 PF13521.6 KPA46189.1 - 0.066 13.5 0.9 4.8 7.4 0.5 2.7 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 KPA46189.1 - 0.085 12.7 0.9 12 5.6 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal SRP54 PF00448.22 KPA46189.1 - 0.1 12.2 0.9 16 5.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 KPA46189.1 - 0.11 12.7 0.0 8.4 6.7 0.0 3.8 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit T2SSE PF00437.20 KPA46189.1 - 0.12 11.4 0.1 5.1 6.1 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KPA46189.1 - 0.15 11.4 0.6 17 4.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 KPA46189.1 - 0.21 11.7 2.8 4.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Mito_carr PF00153.27 KPA46191.1 - 4.2e-52 174.0 6.2 6.9e-18 64.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPA46191.1 - 0.038 13.1 5.0 0.089 11.9 0.0 3.0 2 1 1 3 3 3 0 Gammaproteobacterial serine protease BUD22 PF09073.10 KPA46193.1 - 2.7e-102 343.4 28.7 3.1e-102 343.1 28.7 1.0 1 0 0 1 1 1 1 BUD22 p450 PF00067.22 KPA46194.1 - 7.3e-50 170.0 0.0 9.3e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Chal_sti_synt_C PF02797.15 KPA46195.1 - 2.4e-22 79.6 0.0 8.8e-22 77.7 0.0 1.8 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 KPA46195.1 - 1.8e-19 70.1 0.1 2.8e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 KPA46195.1 - 0.00044 19.7 0.0 0.00067 19.0 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 KPA46195.1 - 0.0041 17.2 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KPA46195.1 - 0.049 13.5 0.2 0.18 11.7 0.1 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Fungal_trans PF04082.18 KPA46196.1 - 1.2e-11 44.2 0.0 2.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA46196.1 - 2e-08 34.2 8.6 3.4e-08 33.5 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vac_ImportDeg PF09783.9 KPA46196.1 - 0.021 14.7 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Vacuolar import and degradation protein TRAUB PF08164.12 KPA46198.1 - 3.6e-29 101.1 0.3 1.2e-28 99.4 0.0 2.1 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KPA46198.1 - 2.5e-23 83.3 0.7 2.5e-23 83.3 0.7 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor ParA PF10609.9 KPA46199.1 - 2.9e-96 321.7 0.1 3.3e-96 321.5 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KPA46199.1 - 1.7e-11 44.2 0.0 1.1e-10 41.6 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KPA46199.1 - 1.4e-09 38.1 0.2 6.1e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 KPA46199.1 - 9.4e-05 21.8 0.0 0.00015 21.2 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 KPA46199.1 - 0.00012 21.9 0.6 0.0059 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KPA46199.1 - 0.00043 19.6 0.3 0.011 14.9 0.0 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KPA46199.1 - 0.00043 19.8 0.1 0.014 14.8 0.1 2.5 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KPA46199.1 - 0.011 15.2 0.3 0.093 12.2 0.1 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KPA46199.1 - 0.023 14.3 0.7 0.054 13.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain Tudor_3 PF18115.1 KPA46200.1 - 5.3e-05 23.0 0.0 9.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KPA46200.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) FlxA PF14282.6 KPA46200.1 - 0.036 14.0 0.2 0.036 14.0 0.2 2.1 2 0 0 2 2 2 0 FlxA-like protein GOLGA2L5 PF15070.6 KPA46200.1 - 0.046 12.4 1.1 0.07 11.8 1.1 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 LBR_tudor PF09465.10 KPA46200.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain IL11 PF07400.11 KPA46200.1 - 0.12 12.0 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Interleukin 11 TCO89 PF10452.9 KPA46201.1 - 0.0018 17.4 1.3 0.041 12.9 0.2 3.4 3 1 1 4 4 4 2 TORC1 subunit TCO89 NicO PF03824.16 KPA46201.1 - 2.5 7.4 4.6 3.9 6.7 4.6 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF4648 PF15505.6 KPA46201.1 - 4.8 8.1 11.2 8.4 7.4 5.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) ABC1 PF03109.16 KPA46202.1 - 7.7e-22 77.7 0.0 2.7e-12 46.9 0.0 3.1 3 0 0 3 3 3 2 ABC1 family POTRA_TamA_1 PF17243.2 KPA46202.1 - 0.003 17.6 0.1 0.13 12.3 0.0 2.6 2 0 0 2 2 2 1 POTRA domain TamA domain 1 APH PF01636.23 KPA46202.1 - 0.021 14.8 0.0 0.059 13.3 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KPA46202.1 - 0.094 12.1 0.0 0.4 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain Cyto_heme_lyase PF01265.17 KPA46203.1 - 2.8e-124 414.4 0.1 3.2e-124 414.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DbpA PF03880.15 KPA46205.1 - 0.031 14.2 0.0 0.079 13.0 0.0 1.7 1 0 0 1 1 1 0 DbpA RNA binding domain UCH_1 PF13423.6 KPA46207.1 - 7.2e-102 341.3 0.0 1.1e-101 340.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KPA46207.1 - 4.5e-22 79.3 0.0 7.6e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KPA46207.1 - 1.9e-05 24.3 0.0 4.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Methyltransf_25 PF13649.6 KPA46208.1 - 1.6e-07 31.9 0.0 2.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA46208.1 - 1.1e-06 29.3 0.0 1.8e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA46208.1 - 7.2e-05 22.6 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA46208.1 - 0.00073 20.1 0.0 0.0012 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA46208.1 - 0.038 13.8 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KPA46209.1 - 8.6e-09 35.4 11.0 1.3e-08 34.8 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA46209.1 - 0.024 13.7 0.5 0.065 12.3 0.5 1.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain PBECR2 PF18810.1 KPA46209.1 - 0.087 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Copper-fist PF00649.18 KPA46210.1 - 2.4e-22 78.1 2.8 2.4e-22 78.1 2.8 3.8 2 1 3 5 5 5 1 Copper fist DNA binding domain ApbA PF02558.16 KPA46211.1 - 1.4e-24 86.5 0.0 1.9e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KPA46211.1 - 1.1e-23 83.8 0.0 1.7e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Glyco_hydro_3 PF00933.21 KPA46212.1 - 7.9e-63 212.7 0.0 1.1e-62 212.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KPA46212.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.25 KPA46212.1 - 0.018 15.3 0.0 0.088 13.0 0.0 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family Fe_hyd_SSU PF02256.17 KPA46212.1 - 0.16 12.1 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Iron hydrogenase small subunit Amidohydro_1 PF01979.20 KPA46213.1 - 3.9e-13 49.4 0.0 6.9e-13 48.6 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPA46213.1 - 6.5e-11 42.4 0.0 1.3e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family NDT80_PhoG PF05224.12 KPA46214.1 - 4e-32 111.9 0.0 6.9e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glucosamine_iso PF01182.20 KPA46215.1 - 1.1e-22 81.1 0.0 1.8e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.16 KPA46216.1 - 2.5e-59 200.6 0.0 4e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KPA46216.1 - 8.7e-40 136.7 0.0 1.3e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase RTT107_BRCT_5 PF16770.5 KPA46217.1 - 3.1e-33 113.6 0.0 1e-29 102.4 0.0 3.9 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KPA46217.1 - 2e-31 107.7 0.3 5.9e-20 71.0 0.1 4.6 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KPA46217.1 - 7.4e-23 80.7 0.2 1.2e-09 38.4 0.0 4.9 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KPA46217.1 - 8.4e-23 80.6 0.1 7.1e-06 26.3 0.1 5.5 5 0 0 5 5 5 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KPA46217.1 - 1.4e-08 34.9 0.7 0.19 12.0 0.0 4.2 4 0 0 4 4 4 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KPA46217.1 - 4.1e-05 23.6 0.1 0.088 12.9 0.1 3.4 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain ALF PF03752.13 KPA46217.1 - 0.19 11.7 1.1 0.73 9.9 0.2 2.2 2 0 0 2 2 2 0 Short repeats of unknown function ESCRT-II PF05871.12 KPA46218.1 - 5.2e-52 175.8 0.0 6.4e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Pyr_redox_2 PF07992.14 KPA46219.1 - 4e-48 164.1 0.2 7e-48 163.3 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KPA46219.1 - 6.3e-21 74.5 0.0 1.2e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KPA46219.1 - 1.4e-18 67.2 1.7 9e-17 61.4 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KPA46219.1 - 6.9e-16 58.3 8.2 9.3e-12 45.1 7.2 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 KPA46219.1 - 9.8e-13 47.9 0.1 5.7e-12 45.4 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KPA46219.1 - 2.4e-11 43.5 0.0 1e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KPA46219.1 - 2e-09 37.1 0.0 4.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KPA46219.1 - 1.9e-05 24.5 0.8 0.033 14.1 0.0 3.7 4 0 0 4 4 4 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KPA46219.1 - 0.0015 18.5 0.0 1.5 8.8 0.0 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KPA46219.1 - 0.0017 18.8 0.0 0.084 13.3 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 KPA46219.1 - 0.02 14.0 0.0 0.17 11.0 0.0 2.1 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KPA46219.1 - 0.041 13.0 2.0 0.12 11.4 0.0 2.4 2 1 1 3 3 3 0 FAD binding domain HI0933_like PF03486.14 KPA46219.1 - 0.12 11.1 0.1 3.7 6.1 0.0 3.1 3 1 1 4 4 4 0 HI0933-like protein DUF2014 PF09427.10 KPA46220.1 - 1.8e-112 375.0 9.0 2.6e-112 374.5 9.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KPA46220.1 - 8.4e-17 60.9 0.9 1.9e-16 59.8 0.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nnf1 PF03980.14 KPA46220.1 - 0.13 12.7 8.1 1.9 8.9 0.4 3.4 4 0 0 4 4 4 0 Nnf1 PRKG1_interact PF15898.5 KPA46220.1 - 4.5 8.2 6.1 0.61 11.0 0.7 2.5 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain UvrD-helicase PF00580.21 KPA46222.1 - 6.8e-65 219.6 3.1 1.7e-63 215.1 0.1 3.0 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KPA46222.1 - 1.1e-64 219.0 0.5 4.2e-64 217.1 0.2 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KPA46222.1 - 5.6e-32 111.1 0.0 2e-31 109.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KPA46222.1 - 1.3e-14 53.7 0.0 2.9e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KPA46222.1 - 1.1e-10 41.6 0.5 1.8e-05 24.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KPA46222.1 - 2.4e-05 24.1 0.1 0.00034 20.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KPA46222.1 - 2.8e-05 24.0 0.9 0.46 10.2 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KPA46222.1 - 0.01 15.6 1.7 0.068 12.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF3517 PF12030.8 KPA46222.1 - 0.011 14.7 0.5 0.037 12.9 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3517) AAA_16 PF13191.6 KPA46222.1 - 0.24 11.8 2.9 4.6 7.6 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain DUF3106 PF11304.8 KPA46223.1 - 0.034 14.6 0.0 0.041 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Opacity PF02462.15 KPA46223.1 - 0.065 13.3 0.1 0.075 13.1 0.1 1.1 1 0 0 1 1 1 0 Opacity family porin protein DASH_Duo1 PF08651.10 KPA46223.1 - 0.093 12.5 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 GMC_oxred_N PF00732.19 KPA46225.1 - 5.2e-61 206.6 0.4 5.2e-61 206.6 0.4 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPA46225.1 - 8.1e-33 114.0 0.1 1.6e-32 113.0 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPA46225.1 - 0.00016 20.9 0.0 0.00076 18.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KPA46225.1 - 0.00019 21.6 0.1 0.00058 20.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA46225.1 - 0.00041 20.0 0.1 0.008 15.8 0.0 2.7 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPA46225.1 - 0.00049 19.4 0.1 0.0012 18.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KPA46225.1 - 0.00075 18.6 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KPA46225.1 - 0.024 13.4 0.1 0.038 12.7 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 KPA46225.1 - 0.045 13.0 0.2 0.18 11.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KPA46225.1 - 0.075 13.3 0.2 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 KPA46225.1 - 0.08 12.2 0.0 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HHH_5 PF14520.6 KPA46225.1 - 0.085 13.5 0.2 9.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain YqzM PF14141.6 KPA46226.1 - 8.9 6.5 7.5 11 6.2 0.5 2.9 2 0 0 2 2 2 0 YqzM-like protein FAD_binding_4 PF01565.23 KPA46227.1 - 2.9e-27 95.1 2.2 5.4e-27 94.2 2.2 1.5 1 0 0 1 1 1 1 FAD binding domain Sugar_tr PF00083.24 KPA46228.1 - 7.3e-98 328.4 30.2 8.7e-98 328.1 30.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA46228.1 - 7.8e-29 100.7 32.0 7.8e-29 100.7 32.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 KPA46229.1 - 1.6e-05 24.9 11.8 3.5e-05 23.8 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPA46229.1 - 3.5e-05 22.8 0.0 5.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KPA46230.1 - 3.4e-64 217.3 0.0 4.6e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KPA46231.1 - 1.8e-47 161.7 0.0 2.7e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KPA46231.1 - 9.7e-27 93.9 0.0 2.4e-26 92.6 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KPA46231.1 - 1.4e-20 73.9 0.0 5.6e-20 72.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain GFO_IDH_MocA PF01408.22 KPA46232.1 - 2.1e-25 89.9 0.9 3.4e-25 89.2 0.9 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPA46232.1 - 5.3e-06 26.4 0.0 9.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.19 KPA46232.1 - 0.056 14.1 0.1 0.17 12.6 0.1 1.8 1 0 0 1 1 1 0 CoA binding domain PPV_E2_N PF00508.17 KPA46232.1 - 0.18 11.1 0.1 0.28 10.5 0.1 1.2 1 0 0 1 1 1 0 E2 (early) protein, N terminal Glyco_hydro_32C PF08244.12 KPA46233.1 - 2.1e-22 79.8 0.7 3.3e-22 79.2 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KPA46233.1 - 1.1e-18 67.9 0.0 2.9e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain DND1_DSRM PF14709.7 KPA46234.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.8 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Ribosomal_S7 PF00177.21 KPA46235.1 - 1.1e-23 83.6 0.0 1.6e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Usp PF00582.26 KPA46236.1 - 3.9e-23 82.5 0.4 4.5e-15 56.4 0.1 2.6 2 0 0 2 2 2 2 Universal stress protein family HET PF06985.11 KPA46237.1 - 4e-13 49.9 6.1 1.4e-10 41.7 0.5 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Gln-synt_N_2 PF16952.5 KPA46238.1 - 0.16 11.8 0.3 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain RRM_1 PF00076.22 KPA46239.1 - 4.7e-82 269.8 8.0 1.1e-22 79.6 0.2 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KPA46239.1 - 1.2e-28 99.1 0.8 5e-28 97.1 0.8 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KPA46239.1 - 2e-10 40.3 0.0 0.017 14.7 0.0 5.0 2 1 3 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPA46239.1 - 6.9e-08 32.5 1.3 0.97 9.6 0.0 5.5 5 1 0 5 5 5 2 RNA recognition motif RRM_occluded PF16842.5 KPA46239.1 - 7.1e-07 29.0 0.2 0.0013 18.5 0.0 3.9 4 0 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KPA46239.1 - 0.002 18.1 0.3 23 5.1 0.0 4.7 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KPA46239.1 - 0.0042 17.1 1.1 1 9.4 0.1 3.4 3 0 0 3 3 3 1 Limkain b1 CbiG_mid PF11761.8 KPA46239.1 - 0.044 13.9 2.8 10 6.3 0.0 3.7 4 0 0 4 4 4 0 Cobalamin biosynthesis central region NPR3 PF03666.13 KPA46239.1 - 0.08 11.7 10.1 0.13 11.0 10.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SOBP PF15279.6 KPA46239.1 - 0.5 10.9 9.7 1.1 9.8 9.7 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein Zip PF02535.22 KPA46239.1 - 3.2 6.9 5.6 6.5 5.9 5.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 KPA46239.1 - 3.7 6.4 7.8 6.5 5.6 7.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2151 PF10221.9 KPA46239.1 - 5.4 5.5 12.0 7.6 5.0 12.0 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Presenilin PF01080.17 KPA46239.1 - 5.8 5.6 12.0 8.8 5.0 12.0 1.2 1 0 0 1 1 1 0 Presenilin YflT PF11181.8 KPA46239.1 - 9.1 6.9 20.0 0.052 14.1 1.2 3.8 4 0 0 4 4 3 0 Heat induced stress protein YflT HECT PF00632.25 KPA46240.1 - 7.3e-77 258.9 0.0 1.4e-76 257.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KPA46240.1 - 0.0036 17.0 0.5 0.0097 15.6 0.5 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif ASRT PF07100.11 KPA46240.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Anabaena sensory rhodopsin transducer Glyco_hydro_125 PF06824.11 KPA46241.1 - 3.3e-169 563.2 0.0 4.2e-169 562.9 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DASH_Dam1 PF08653.10 KPA46241.1 - 0.051 13.4 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 DASH complex subunit Dam1 ETF_QO PF05187.13 KPA46242.1 - 1.6e-48 163.1 0.9 2.6e-48 162.5 0.9 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 KPA46242.1 - 3.3e-08 33.6 0.0 8.5e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA46242.1 - 1.3e-06 28.3 0.6 0.0002 21.1 0.2 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA46242.1 - 7.1e-05 22.2 0.0 0.0002 20.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPA46242.1 - 9.1e-05 21.8 0.0 0.00034 19.9 0.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KPA46242.1 - 0.00012 21.3 1.0 0.0062 15.7 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KPA46242.1 - 0.00055 18.8 0.3 0.00083 18.2 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KPA46242.1 - 0.00059 19.2 0.1 0.00094 18.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KPA46242.1 - 0.0006 20.3 0.1 0.38 11.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA46242.1 - 0.0013 18.7 0.1 0.0056 16.7 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KPA46242.1 - 0.0036 16.6 0.1 0.0052 16.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPA46242.1 - 0.0083 15.0 0.0 2.2 7.0 0.1 2.3 1 1 1 2 2 2 2 Tryptophan halogenase Fer4_7 PF12838.7 KPA46242.1 - 0.0097 16.5 1.0 0.027 15.1 1.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_oxidored PF12831.7 KPA46242.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KPA46242.1 - 0.038 13.3 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Internalin_N PF12354.8 KPA46242.1 - 0.047 13.8 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal Lycopene_cycl PF05834.12 KPA46242.1 - 0.071 12.1 0.3 0.1 11.6 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_2 PF12797.7 KPA46242.1 - 0.15 12.2 0.7 0.44 10.8 0.7 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain GIDA PF01134.22 KPA46242.1 - 0.2 10.7 0.2 0.31 10.1 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Metaviral_G PF09595.10 KPA46242.1 - 1.3 9.1 6.0 2.5 8.1 6.0 1.4 1 0 0 1 1 1 0 Metaviral_G glycoprotein TBP PF00352.21 KPA46243.1 - 1.4e-67 223.6 0.1 7e-33 112.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KPA46243.1 - 0.00011 22.2 0.0 0.22 11.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KPA46243.1 - 0.12 12.2 0.1 0.67 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DAO PF01266.24 KPA46244.1 - 1.4e-42 146.6 0.0 1.6e-42 146.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPA46244.1 - 8.2e-06 25.9 0.1 0.073 13.1 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 KPA46244.1 - 0.00026 20.2 0.0 0.00059 19.0 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KPA46244.1 - 0.00036 20.7 0.0 0.00084 19.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA46244.1 - 0.00056 19.2 0.1 0.042 13.1 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_G2 PF11962.8 KPA46244.1 - 0.017 14.5 0.2 0.028 13.8 0.2 1.3 1 0 0 1 1 1 0 Peptidase_G2, IMC autoproteolytic cleavage domain FAD_binding_2 PF00890.24 KPA46244.1 - 0.041 13.0 0.0 0.37 9.8 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Formyl_trans_N PF00551.19 KPA46245.1 - 2.1e-34 118.8 0.0 2.5e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Surp PF01805.20 KPA46246.1 - 3.8e-10 39.6 0.0 7.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Surp module POTRA_2 PF08479.11 KPA46246.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type Copper-fist PF00649.18 KPA46247.1 - 1.5e-18 66.0 0.6 3.6e-18 64.7 0.6 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain Metallothio_PEC PF02068.16 KPA46247.1 - 6.2 7.2 44.0 0.1 13.0 2.7 4.2 4 0 0 4 4 4 0 Plant PEC family metallothionein Metallothio_2 PF01439.18 KPA46247.1 - 8.8 7.3 30.2 0.16 12.9 5.3 4.2 4 1 0 4 4 4 0 Metallothionein Methyltransf_16 PF10294.9 KPA46249.1 - 5.2e-13 49.1 0.0 6.8e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KPA46249.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 KPA46249.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 KPA46249.1 - 0.14 12.9 0.1 1.4 9.6 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain PhyH PF05721.13 KPA46250.1 - 5.1e-11 43.2 0.1 1.1e-10 42.2 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.18 KPA46251.1 - 7e-12 44.9 0.5 2.2e-11 43.3 0.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPA46251.1 - 9.4e-08 32.1 8.5 0.0052 17.2 3.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA46251.1 - 2.7e-05 24.6 8.1 0.011 16.5 2.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPA46251.1 - 0.00017 21.9 13.4 0.00053 20.3 1.8 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KPA46251.1 - 0.064 13.6 0.4 0.74 10.2 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KPA46251.1 - 3.2 7.8 5.5 4.6 7.2 2.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type NMO PF03060.15 KPA46252.1 - 2.4e-53 181.7 0.4 2.4e-52 178.4 0.4 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KPA46252.1 - 2.5e-12 46.5 0.6 1.9e-10 40.3 0.6 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KPA46252.1 - 0.00088 18.4 0.4 0.0014 17.7 0.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase F-box-like PF12937.7 KPA46253.1 - 0.0034 17.2 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA46253.1 - 0.04 13.8 0.1 0.092 12.7 0.1 1.6 1 0 0 1 1 1 0 F-box domain Med13_C PF06333.12 KPA46256.1 - 1.3e-84 284.3 4.7 1.3e-84 284.3 4.7 3.4 3 1 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KPA46256.1 - 3.9e-30 105.3 2.6 3.9e-30 105.3 2.6 1.7 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KPA46256.1 - 1.8e-14 54.1 0.6 1.1e-05 25.4 0.2 3.4 2 1 1 3 3 3 2 MID domain of medPIWI NUC153 PF08159.12 KPA46257.1 - 3.5e-11 42.7 1.6 6.3e-11 41.9 1.6 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KPA46257.1 - 2.6e-07 31.2 0.1 0.03 15.2 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA46257.1 - 0.13 12.6 0.0 0.42 10.9 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPA46257.1 - 0.14 12.0 0.1 1 9.2 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Zn_peptidase PF04228.13 KPA46258.1 - 0.089 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase 7TM_GPCR_Srd PF10317.9 KPA46258.1 - 0.14 11.3 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF1902 PF08972.11 KPA46259.1 - 0.2 11.7 2.6 8.3 6.5 0.2 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) MCD_N PF17408.2 KPA46259.1 - 4.3 7.6 17.7 0.82 9.8 2.0 4.9 3 2 1 5 5 5 0 Malonyl-CoA decarboxylase N-terminal domain Ribosomal_L33 PF00471.20 KPA46260.1 - 2e-05 24.9 0.0 2.4e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L33 Aminotran_1_2 PF00155.21 KPA46261.1 - 2.4e-42 145.4 0.0 3.2e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KPA46261.1 - 0.027 13.0 0.0 0.05 12.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RPN7 PF10602.9 KPA46262.1 - 3.9e-50 170.0 0.4 8.6e-50 168.8 0.0 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KPA46262.1 - 2.1e-14 53.9 0.0 6.7e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 PCI domain Pox_MCEL PF03291.16 KPA46263.1 - 5.7e-71 239.3 0.0 3.8e-48 164.3 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KPA46263.1 - 4.2e-10 40.2 0.0 0.00013 22.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KPA46263.1 - 6.9e-09 36.3 2.0 0.0013 19.4 0.0 3.2 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_31 PF13847.6 KPA46263.1 - 1.2e-07 31.7 0.0 6.6e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KPA46263.1 - 7.9e-07 29.6 0.0 2.4e-05 24.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPA46263.1 - 1.3e-06 28.3 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KPA46263.1 - 0.0081 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Raftlin PF15250.6 KPA46263.1 - 0.032 13.0 1.8 0.083 11.6 0.0 1.9 2 0 0 2 2 2 0 Raftlin FAM92 PF06730.11 KPA46263.1 - 0.037 13.5 1.9 0.056 12.9 1.9 1.2 1 0 0 1 1 1 0 FAM92 protein Methyltransf_4 PF02390.17 KPA46263.1 - 0.16 11.5 0.0 2.1 7.8 0.0 2.2 1 1 0 1 1 1 0 Putative methyltransferase EF_assoc_2 PF08356.12 KPA46264.1 - 2.9e-34 116.9 0.0 5.8e-34 116.0 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KPA46264.1 - 5.5e-30 102.8 0.1 1e-29 101.9 0.1 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KPA46264.1 - 3.1e-22 78.9 0.0 1.6e-14 53.9 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KPA46264.1 - 1.1e-12 48.3 0.0 1.2e-08 35.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 KPA46264.1 - 3.4e-09 35.6 3.9 0.00035 19.9 0.1 2.8 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 KPA46264.1 - 1e-07 32.0 0.0 0.0008 19.5 0.0 3.7 3 1 0 3 3 3 2 50S ribosome-binding GTPase EF-hand_6 PF13405.6 KPA46264.1 - 1.1e-07 31.2 2.5 0.0085 15.9 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KPA46264.1 - 3.1e-07 30.8 0.8 0.00057 20.3 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.23 KPA46264.1 - 3.1e-06 27.3 0.0 0.004 17.2 0.1 3.1 2 1 1 3 3 3 1 Dynamin family AAA_16 PF13191.6 KPA46264.1 - 0.00028 21.3 0.0 0.032 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain EF-hand_5 PF13202.6 KPA46264.1 - 0.00028 20.2 7.0 0.063 12.8 3.1 2.6 2 0 0 2 2 2 2 EF hand AAA_22 PF13401.6 KPA46264.1 - 0.00031 21.0 0.0 0.098 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPA46264.1 - 0.00075 19.2 0.0 0.053 13.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KPA46264.1 - 0.0013 18.3 0.0 4.5 6.8 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPA46264.1 - 0.0021 18.0 0.0 1.8 8.5 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase Septin PF00735.18 KPA46264.1 - 0.0033 16.7 0.0 0.47 9.7 0.0 2.3 2 0 0 2 2 2 1 Septin EF-hand_10 PF14788.6 KPA46264.1 - 0.012 15.4 1.7 0.27 11.1 0.1 2.4 2 0 0 2 2 2 0 EF hand AAA_28 PF13521.6 KPA46264.1 - 0.015 15.5 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPA46264.1 - 0.038 13.7 0.0 4 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KPA46264.1 - 0.041 14.4 0.0 2.4 8.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter SPARC_Ca_bdg PF10591.9 KPA46264.1 - 0.069 13.5 0.3 4.7 7.6 0.1 2.9 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KPA46264.1 - 0.11 12.4 4.0 7.9 6.4 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair RNA_helicase PF00910.22 KPA46264.1 - 0.12 12.8 0.0 25 5.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KPA46264.1 - 0.15 12.2 0.0 3.8 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KPA46265.1 - 4.3e-11 43.2 20.4 1.6e-05 25.5 0.2 5.7 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA46265.1 - 9.8e-09 35.4 0.1 0.0036 17.6 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KPA46265.1 - 0.0012 17.0 0.0 0.0025 15.9 0.0 1.4 1 1 1 2 2 2 1 IKI3 family eIF2A PF08662.11 KPA46265.1 - 0.0037 17.2 0.0 0.013 15.4 0.0 1.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KPA46265.1 - 0.021 13.4 0.0 0.044 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain PD40 PF07676.12 KPA46265.1 - 0.038 13.9 0.0 5.8 7.0 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Arrestin_C PF02752.22 KPA46266.1 - 1.9e-14 54.2 0.0 3.8e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KPA46266.1 - 9.3e-13 48.5 0.0 1.5e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KPA46266.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like PH PF00169.29 KPA46267.1 - 0.00038 20.9 0.0 0.00065 20.2 0.0 1.4 1 0 0 1 1 1 1 PH domain Clr5 PF14420.6 KPA46268.1 - 6.9e-17 61.4 0.8 1.1e-16 60.8 0.8 1.3 1 0 0 1 1 1 1 Clr5 domain Fapy_DNA_glyco PF01149.24 KPA46270.1 - 2.3e-37 128.2 0.1 4.2e-37 127.3 0.1 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KPA46270.1 - 5.7e-22 77.5 0.0 1e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KPA46270.1 - 0.01 14.6 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 KPA46270.1 - 0.11 12.9 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S13/S18 DHBP_synthase PF00926.19 KPA46271.1 - 7.3e-79 263.8 0.0 8.5e-79 263.6 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Big_6 PF17936.1 KPA46271.1 - 0.038 14.3 0.0 3.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial Ig domain Methyltransf_23 PF13489.6 KPA46272.1 - 3.8e-19 69.1 0.0 5.3e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA46272.1 - 2.6e-16 60.0 0.0 6.6e-16 58.8 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA46272.1 - 2.7e-15 56.8 0.0 5.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA46272.1 - 1.5e-14 54.0 0.0 2e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA46272.1 - 1.1e-11 45.3 0.0 1.7e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KPA46272.1 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KPA46272.1 - 0.00033 19.7 0.0 0.00048 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KPA46272.1 - 0.0048 16.5 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KPA46272.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KPA46272.1 - 0.11 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain NodS PF05401.11 KPA46272.1 - 0.2 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 KPA46272.1 - 0.26 11.2 0.0 0.48 10.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KPA46272.1 - 0.27 11.2 0.0 0.44 10.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S10 PF00450.22 KPA46273.1 - 2.8e-78 264.2 0.0 4.9e-78 263.4 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase zf-Nse PF11789.8 KPA46274.1 - 6.3e-22 77.2 0.3 6.3e-22 77.2 0.3 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KPA46274.1 - 0.0011 18.9 0.4 0.0022 18.0 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.20 KPA46274.1 - 0.0013 18.5 0.3 0.0025 17.5 0.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 KPA46274.1 - 0.0047 16.8 0.2 0.0089 15.8 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF241 PF03087.14 KPA46274.1 - 0.0055 16.6 3.1 0.011 15.6 3.1 1.5 1 0 0 1 1 1 1 Arabidopsis protein of unknown function MerR-DNA-bind PF09278.11 KPA46274.1 - 0.03 14.9 1.7 0.03 14.9 1.7 2.9 3 1 0 3 3 3 0 MerR, DNA binding COG5 PF10392.9 KPA46274.1 - 0.2 11.9 6.7 2.2 8.5 6.5 2.3 1 1 0 1 1 1 0 Golgi transport complex subunit 5 PAS_9 PF13426.7 KPA46275.1 - 1.5e-12 47.7 0.0 2.5e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KPA46275.1 - 0.085 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 KPA46275.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.12 KPA46275.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.7 1 1 0 1 1 1 0 PAS fold PAS PF00989.25 KPA46275.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 PAS fold Atx10homo_assoc PF09759.9 KPA46276.1 - 2e-11 43.7 0.0 7.4e-11 41.9 0.0 1.9 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Zip PF02535.22 KPA46276.1 - 0.061 12.5 15.5 0.11 11.7 15.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PNP_UDP_1 PF01048.20 KPA46277.1 - 8.7e-40 136.4 0.4 1.1e-39 136.0 0.4 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Methyltransf_33 PF10017.9 KPA46278.1 - 8.2e-84 281.4 0.0 9.2e-84 281.2 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Fungal_trans_2 PF11951.8 KPA46279.1 - 5.4e-24 84.7 0.1 2.2e-23 82.7 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 KPA46281.1 - 3.9e-32 112.2 0.0 5e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA46281.1 - 2.1e-06 27.2 0.3 0.0008 18.7 0.1 3.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPA46281.1 - 4.7e-06 26.7 0.2 0.019 15.0 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KPA46281.1 - 0.0016 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_8 PF13450.6 KPA46281.1 - 0.002 18.3 0.0 0.0047 17.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KPA46281.1 - 0.0092 16.4 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KPA46281.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KPA46281.1 - 0.013 16.1 0.0 0.048 14.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPA46281.1 - 0.025 13.7 0.1 0.89 8.6 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KPA46281.1 - 0.026 13.4 0.2 5.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 KPA46281.1 - 0.033 14.4 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.24 KPA46281.1 - 0.06 12.4 1.2 0.3 10.1 1.2 1.9 1 1 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 KPA46281.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase F420_oxidored PF03807.17 KPA46281.1 - 0.11 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 KPA46281.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 ThiF family FAD_binding_1 PF00667.20 KPA46282.1 - 1.4e-67 227.5 0.0 2.9e-67 226.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KPA46282.1 - 1.1e-09 38.9 0.0 2.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 KPA46282.1 - 5.8e-08 33.0 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 KPA46282.1 - 1.8e-06 28.2 0.1 4.2e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KPA46282.1 - 0.00014 21.8 0.1 0.00035 20.4 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain MFS_1 PF07690.16 KPA46284.1 - 7.6e-37 127.0 50.6 7.6e-37 127.0 50.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily RVT_thumb PF06817.14 KPA46284.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase thumb domain Fungal_trans PF04082.18 KPA46285.1 - 4.5e-18 65.2 0.0 6.2e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA46285.1 - 1.6e-08 34.5 11.8 2.8e-08 33.7 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 KPA46286.1 - 5.9e-10 39.2 0.0 9.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA46286.1 - 0.0012 19.6 0.0 0.003 18.3 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA46286.1 - 0.013 15.3 0.0 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KPA46286.1 - 0.17 12.5 0.0 0.33 11.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CDC45 PF02724.14 KPA46287.1 - 1.2e-253 843.1 0.0 4.8e-253 841.2 0.0 2.4 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.12 KPA46287.1 - 0.0032 17.2 8.5 0.0032 17.2 8.5 2.3 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KPA46287.1 - 0.25 10.6 24.5 0.037 13.4 9.3 2.1 2 0 0 2 2 2 0 BUD22 FAM60A PF15396.6 KPA46287.1 - 5.6 6.9 7.3 0.15 12.0 0.8 1.6 2 0 0 2 2 2 0 Protein Family FAM60A EF-hand_7 PF13499.6 KPA46288.1 - 3.8e-24 84.9 8.3 8.3e-16 58.2 1.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KPA46288.1 - 2.2e-23 80.0 12.5 1.2e-07 30.7 0.2 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KPA46288.1 - 8.1e-23 78.4 6.4 6.6e-06 25.6 0.1 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KPA46288.1 - 2e-16 58.7 11.8 0.00013 21.2 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KPA46288.1 - 4.9e-14 51.9 10.7 2.1e-05 24.2 0.5 3.8 2 2 1 3 3 3 3 EF-hand domain pair Methyltransf_16 PF10294.9 KPA46288.1 - 1.3e-11 44.5 0.0 1e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase EF-hand_4 PF12763.7 KPA46288.1 - 8.3e-07 28.9 8.0 0.023 14.6 0.2 4.2 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KPA46288.1 - 0.0011 19.2 0.6 0.026 14.8 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 KPA46288.1 - 0.057 13.3 1.5 1 9.3 0.1 3.5 3 0 0 3 3 3 0 EF hand SPARC_Ca_bdg PF10591.9 KPA46288.1 - 0.091 13.1 2.9 4.5 7.6 0.4 3.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Aconitase PF00330.20 KPA46289.1 - 6.5e-161 536.4 0.0 7.9e-161 536.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KPA46289.1 - 2.6e-40 137.8 0.0 5.9e-40 136.6 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2418 PF10332.9 KPA46291.1 - 1.7e-34 118.2 0.6 2.6e-34 117.6 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.17 KPA46292.1 - 4.5e-34 116.7 0.1 6.6e-34 116.1 0.1 1.2 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit SHMT PF00464.19 KPA46292.1 - 0.16 10.6 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase E1_DerP2_DerF2 PF02221.15 KPA46293.1 - 1.3e-26 93.7 0.1 1.6e-26 93.4 0.1 1.1 1 0 0 1 1 1 1 ML domain Alph_Pro_TM PF09608.10 KPA46293.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) PapG_N PF03627.13 KPA46293.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 PapG carbohydrate binding domain PHD PF00628.29 KPA46294.1 - 2.8e-08 33.5 9.4 5.7e-08 32.5 9.4 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 KPA46294.1 - 4.8e-06 27.1 0.0 1.5e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 SET domain Glycos_transf_4 PF00953.21 KPA46295.1 - 1.6e-29 103.0 8.8 1.6e-29 103.0 8.8 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 4 SNARE_assoc PF09335.11 KPA46295.1 - 0.016 15.7 0.6 0.016 15.7 0.6 2.9 3 0 0 3 3 3 0 SNARE associated Golgi protein DUF2107 PF09880.9 KPA46295.1 - 9.5 6.4 8.6 0.3 11.2 0.3 2.8 4 0 0 4 4 4 0 Predicted membrane protein (DUF2107) K_trans PF02705.16 KPA46296.1 - 5.5e-180 599.4 15.1 6.6e-180 599.2 15.1 1.0 1 0 0 1 1 1 1 K+ potassium transporter DUF485 PF04341.12 KPA46296.1 - 3.7 7.6 12.4 15 5.6 0.0 4.2 2 1 1 3 3 3 0 Protein of unknown function, DUF485 Herpes_LMP1 PF05297.11 KPA46296.1 - 7.4 5.7 10.0 16 4.5 10.0 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Transglut_core PF01841.19 KPA46297.1 - 4.8e-10 39.9 0.0 8.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KPA46298.1 - 2.1e-07 30.7 0.7 4.4e-07 29.7 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA46298.1 - 8.1e-07 28.8 0.4 3.1e-06 26.9 0.4 2.1 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 KPA46298.1 - 0.0009 19.2 0.0 0.0025 17.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like domain LRR_4 PF12799.7 KPA46298.1 - 4.8 7.7 8.6 20 5.8 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Iso_dh PF00180.20 KPA46299.1 - 5.3e-101 338.2 0.0 6.6e-101 337.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.7 KPA46299.1 - 0.015 15.3 0.0 0.064 13.4 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Phage_30_3 PF08010.11 KPA46299.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Sec5 PF15469.6 KPA46300.1 - 8e-37 126.9 0.0 2.5e-36 125.3 0.0 1.9 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KPA46300.1 - 7.5e-05 22.7 1.4 0.00064 19.8 0.1 3.0 2 0 0 2 2 2 1 Vps51/Vps67 Sec15 PF04091.12 KPA46300.1 - 0.17 11.3 0.9 0.35 10.2 0.3 1.7 1 1 1 2 2 2 0 Exocyst complex subunit Sec15-like TRAF6_Z2 PF18048.1 KPA46301.1 - 0.085 13.0 0.9 0.23 11.6 0.9 1.7 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_6 PF13912.6 KPA46301.1 - 0.54 10.3 2.3 1.9 8.6 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_clus PF00172.18 KPA46301.1 - 0.55 10.4 12.7 0.027 14.6 6.9 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.14 KPA46302.1 - 1.6e-10 41.3 0.0 6.5e-10 39.3 0.0 1.9 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.20 KPA46302.1 - 2.2e-07 30.6 0.1 4.6e-07 29.5 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.6 KPA46302.1 - 0.032 14.7 0.0 0.089 13.3 0.0 1.7 1 1 0 1 1 1 0 CoA binding domain Solute_trans_a PF03619.16 KPA46303.1 - 4.7e-100 334.5 10.3 5.5e-100 334.3 10.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4293 PF14126.6 KPA46303.1 - 0.35 11.1 5.2 0.065 13.5 1.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) GTP_EFTU PF00009.27 KPA46305.1 - 7.8e-67 224.6 0.4 1.1e-66 224.1 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KPA46305.1 - 7.6e-33 112.9 0.0 2.7e-32 111.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KPA46305.1 - 6e-21 74.3 0.0 1.9e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KPA46305.1 - 1.1e-13 51.4 0.2 4.5e-13 49.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KPA46305.1 - 6.1e-12 45.5 0.0 2.1e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KPA46305.1 - 0.00032 20.8 0.3 0.00076 19.6 0.3 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAD_M PF08527.10 KPA46305.1 - 0.099 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain PduV-EutP PF10662.9 KPA46305.1 - 0.13 12.0 0.2 0.5 10.1 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FAST_1 PF06743.15 KPA46305.1 - 0.17 11.9 0.0 2.8 8.0 0.1 2.3 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 RRM_1 PF00076.22 KPA46306.1 - 3e-08 33.3 0.1 5.4e-06 26.1 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KPA46306.1 - 8.7e-08 32.4 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 KPA46306.1 - 2.7e-07 30.5 0.0 1.7e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 KPA46306.1 - 9.9e-05 22.1 5.6 0.00019 21.3 5.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_occluded PF16842.5 KPA46306.1 - 0.0023 17.8 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif zf_CCCH_4 PF18345.1 KPA46306.1 - 0.021 14.9 3.1 0.046 13.8 3.1 1.6 1 0 0 1 1 1 0 Zinc finger domain PHM7_cyt PF14703.6 KPA46306.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KPA46306.1 - 0.17 11.9 6.7 2.6 8.1 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif Atg14 PF10186.9 KPA46306.1 - 1.5 7.8 7.5 2.2 7.3 7.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MTHFR PF02219.17 KPA46307.1 - 1e-113 379.5 0.0 1.5e-113 378.9 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3425 PF11905.8 KPA46308.1 - 2e-11 43.9 1.6 5.3e-10 39.3 1.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 KPA46308.1 - 1.7 8.8 6.9 3.2 7.9 6.9 1.4 1 0 0 1 1 1 0 Basic region leucine zipper MFS_1 PF07690.16 KPA46311.1 - 1.2e-27 96.8 26.7 2.1e-27 96.0 26.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily HTH_Tnp_Tc5 PF03221.16 KPA46312.1 - 3.8e-18 65.3 0.7 3.6e-08 33.3 0.1 4.7 4 0 0 4 4 4 3 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.11 KPA46312.1 - 2e-15 56.4 1.0 2e-15 56.4 1.0 2.5 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KPA46312.1 - 1.9e-05 24.4 0.5 4.9e-05 23.1 0.5 1.7 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 KPA46312.1 - 0.0024 18.2 14.0 0.041 14.3 3.9 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA46312.1 - 0.0033 18.1 3.8 0.0033 18.1 3.8 4.2 3 0 0 3 3 3 1 C2H2-type zinc finger DUF4667 PF15700.5 KPA46312.1 - 0.033 14.3 8.5 0.071 13.2 8.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) GATA PF00320.27 KPA46313.1 - 1.3e-29 101.5 16.6 1.5e-15 56.5 3.0 2.7 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KPA46313.1 - 5.5e-07 29.0 2.0 0.0054 16.2 0.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KPA46313.1 - 0.00029 20.9 1.8 0.61 10.2 0.2 2.5 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 KPA46313.1 - 0.00073 19.6 6.7 0.085 13.0 0.1 3.2 3 0 0 3 3 3 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 KPA46313.1 - 0.0045 17.1 5.7 0.35 11.1 0.7 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 KPA46313.1 - 0.005 16.7 6.0 0.27 11.2 0.9 2.7 2 0 0 2 2 2 2 Putative transposase DNA-binding domain zf-RRN7 PF11781.8 KPA46313.1 - 0.072 12.8 0.5 0.072 12.8 0.5 3.1 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 KPA46313.1 - 0.077 13.0 14.6 4.3 7.4 1.5 3.3 1 1 1 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 KPA46313.1 - 0.079 12.8 4.6 2.2 8.2 0.4 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-ribbon_3 PF13248.6 KPA46313.1 - 0.82 9.2 10.6 23 4.6 0.2 4.3 4 0 0 4 4 4 0 zinc-ribbon domain ADK_lid PF05191.14 KPA46313.1 - 2.5 8.2 6.0 4.1 7.5 0.3 3.6 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 KPA46313.1 - 3 8.0 13.9 0.066 13.3 0.8 3.5 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger zinc_ribbon_2 PF13240.6 KPA46313.1 - 6.5 6.6 11.5 17 5.3 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain UPF0492 PF15744.5 KPA46314.1 - 0.88 8.7 5.8 1.3 8.2 5.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Baculo_PEP_C PF04513.12 KPA46315.1 - 0.079 13.0 0.4 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SR-25 PF10500.9 KPA46315.1 - 3.6 7.1 11.3 5.4 6.6 5.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SMC_Nse1 PF07574.13 KPA46316.1 - 1.6e-71 240.2 0.4 2e-71 239.9 0.4 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KPA46316.1 - 3.5e-15 56.0 8.3 5.3e-15 55.5 8.3 1.3 1 0 0 1 1 1 1 RING-like domain C1_2 PF03107.16 KPA46316.1 - 0.0079 16.5 1.3 0.0079 16.5 1.3 2.0 2 0 0 2 2 2 1 C1 domain PaaX PF07848.12 KPA46316.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 PaaX-like protein DUF4113 PF13438.6 KPA46316.1 - 0.12 12.5 0.6 0.32 11.1 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) zf-HC5HC2H_2 PF13832.6 KPA46316.1 - 0.42 10.8 4.5 0.96 9.6 4.5 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KPA46316.1 - 0.55 10.5 5.6 0.2 11.9 2.7 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_2 PF13923.6 KPA46316.1 - 2.1 8.2 6.6 3.5 7.6 6.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPA46316.1 - 9 6.7 8.2 16 5.9 8.2 1.4 1 0 0 1 1 1 0 Ring finger domain Clr2_transil PF16761.5 KPA46317.1 - 5e-08 33.6 2.7 2.2e-07 31.6 2.7 2.1 1 1 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KPA46317.1 - 6.8e-06 26.9 0.0 6.8e-06 26.9 0.0 3.6 3 2 0 3 3 3 1 Transcription-silencing protein Clr2 TFIIA PF03153.13 KPA46317.1 - 0.11 12.4 24.0 0.17 11.8 24.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 KPA46317.1 - 2.1 6.5 17.3 2.8 6.1 17.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HypA PF01155.19 KPA46318.1 - 0.011 15.7 22.4 0.11 12.6 2.3 3.4 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IBR PF01485.21 KPA46318.1 - 0.85 9.9 27.4 0.91 9.8 4.8 3.5 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain DZR PF12773.7 KPA46318.1 - 1.4 9.0 34.2 5.4 7.1 15.2 3.7 2 2 0 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.16 KPA46318.1 - 2.6 8.3 21.3 0.66 10.2 2.8 3.3 2 1 1 3 3 3 0 FYVE-type zinc finger F-box-like PF12937.7 KPA46319.1 - 2.6e-08 33.6 0.0 5.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA46319.1 - 1.2e-06 28.3 1.9 1.2e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 F-box domain UIM PF02809.20 KPA46319.1 - 0.081 12.9 11.5 1.5 8.9 0.3 3.6 3 0 0 3 3 3 0 Ubiquitin interaction motif Asp PF00026.23 KPA46321.1 - 2.9e-10 40.1 0.0 2.3e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Rax2 PF12768.7 KPA46321.1 - 0.00036 20.1 0.0 0.00076 19.0 0.0 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SKG6 PF08693.10 KPA46321.1 - 0.0018 17.6 0.7 0.0034 16.8 0.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain FAD_binding_1 PF00667.20 KPA46322.1 - 1.3e-30 106.6 0.0 2.3e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KPA46322.1 - 4e-28 98.4 0.0 6.2e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KPA46322.1 - 8.6e-16 58.5 0.0 1.8e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain RRM_1 PF00076.22 KPA46323.1 - 1.3e-30 105.0 0.1 3.3e-15 55.6 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPA46323.1 - 3.6e-05 23.8 0.0 0.052 13.7 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KPA46323.1 - 3.7e-05 23.3 0.0 0.59 9.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4783 PF16022.5 KPA46323.1 - 0.058 13.6 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) Limkain-b1 PF11608.8 KPA46323.1 - 0.065 13.3 0.2 19 5.4 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 DbpA PF03880.15 KPA46323.1 - 0.1 12.6 0.1 15 5.7 0.0 2.7 3 0 0 3 3 3 0 DbpA RNA binding domain Lipoprotein_8 PF02030.15 KPA46323.1 - 0.11 11.2 0.8 0.17 10.6 0.8 1.2 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) TEX19 PF15553.6 KPA46323.1 - 9.2 6.2 5.9 1.5 8.8 1.2 2.0 2 1 0 2 2 2 0 Testis-expressed protein 19 ETF PF01012.21 KPA46324.1 - 1.1e-43 149.3 1.3 1.6e-43 148.7 1.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.18 KPA46324.1 - 2.6e-31 108.1 0.6 5e-31 107.2 0.6 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CPSase_sm_chain PF00988.22 KPA46325.1 - 4.2e-47 159.2 0.0 1.8e-46 157.1 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KPA46325.1 - 8.4e-47 159.4 0.0 1.1e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KPA46325.1 - 1.9e-05 24.5 0.2 0.00084 19.2 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KPA46325.1 - 0.0084 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family SAP PF02037.27 KPA46326.1 - 1.5e-11 43.8 0.2 2.3e-11 43.2 0.2 1.3 1 0 0 1 1 1 1 SAP domain DJ-1_PfpI PF01965.24 KPA46327.1 - 3e-13 49.9 0.1 6.2e-13 48.9 0.1 1.5 2 0 0 2 2 2 1 DJ-1/PfpI family ThiJ_like PF17124.5 KPA46327.1 - 0.00016 21.4 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like Hamartin PF04388.12 KPA46328.1 - 2.8e-28 99.1 4.2 2.8e-28 99.1 4.2 3.3 1 1 2 3 3 3 2 Hamartin protein HAP1_N PF04849.13 KPA46328.1 - 0.00098 18.4 11.5 0.00098 18.4 11.5 3.1 1 1 1 2 2 2 1 HAP1 N-terminal conserved region Fungal_TACC PF12709.7 KPA46328.1 - 0.0031 17.9 4.3 0.0031 17.9 4.3 3.1 3 0 0 3 3 3 1 Fungal Transforming acidic coiled-coil (TACC) proteins Sec7_N PF12783.7 KPA46328.1 - 0.0081 16.1 0.1 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Urb2 PF10441.9 KPA46328.1 - 0.048 13.6 3.2 1.6 8.6 0.0 3.3 3 0 0 3 3 3 0 Urb2/Npa2 family Prefoldin PF02996.17 KPA46328.1 - 1.8 8.5 10.5 0.51 10.3 4.1 2.9 2 0 0 2 2 2 0 Prefoldin subunit Prominin PF05478.11 KPA46328.1 - 3 5.7 9.2 7.5 4.4 8.3 2.0 2 0 0 2 2 2 0 Prominin VPS11_C PF12451.8 KPA46328.1 - 9.2 6.6 5.8 1.9 8.8 0.6 2.7 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Ras PF00071.22 KPA46329.1 - 1.8e-40 138.2 0.0 1.8e-39 135.0 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KPA46329.1 - 4.9e-31 107.4 0.0 7.3e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPA46329.1 - 5.4e-10 39.0 0.0 9e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KPA46329.1 - 0.00066 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KPA46329.1 - 0.0095 16.3 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KPA46329.1 - 0.023 14.1 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 KPA46329.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DLIC PF05783.11 KPA46329.1 - 0.13 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_33 PF13671.6 KPA46329.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RTP1_C2 PF10304.9 KPA46329.1 - 0.22 11.3 0.2 0.45 10.3 0.2 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 QRPTase_C PF01729.19 KPA46330.1 - 8.9e-54 181.8 0.1 1.1e-53 181.5 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KPA46330.1 - 1.8e-16 60.0 0.0 8.3e-16 57.8 0.0 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Cu_amine_oxid PF01179.20 KPA46331.1 - 3.7e-148 493.8 0.0 4.4e-148 493.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KPA46331.1 - 1.4e-05 25.2 0.0 2.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CAP PF00188.26 KPA46332.1 - 9.9e-21 74.9 2.6 1.4e-20 74.4 2.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CHCH PF06747.13 KPA46334.1 - 2.4e-08 33.9 13.0 8.4e-07 29.0 3.4 2.5 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.10 KPA46334.1 - 0.00038 20.4 9.2 0.023 14.7 0.5 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KPA46334.1 - 0.00049 20.1 4.1 0.23 11.5 1.2 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KPA46334.1 - 0.15 12.4 6.4 5.7 7.3 0.8 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Nup54 PF13874.6 KPA46335.1 - 3.9e-38 130.7 2.5 8.8e-38 129.6 0.5 2.3 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KPA46335.1 - 4.5e-15 54.9 4.2 4.5e-15 54.9 4.2 1.9 2 0 0 2 2 2 1 NUP57/Nup54 C-terminal domain DivIVA PF05103.13 KPA46335.1 - 0.0019 18.3 3.9 0.012 15.7 0.3 2.2 1 1 0 2 2 2 1 DivIVA protein Nucleoporin_FG PF13634.6 KPA46335.1 - 0.0024 18.7 14.5 0.0036 18.1 14.5 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeat region Adhesin_P1_N PF18652.1 KPA46335.1 - 0.029 14.4 3.8 0.077 13.0 0.6 2.5 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain DUF3782 PF12644.7 KPA46335.1 - 0.1 12.7 0.5 0.72 10.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) Nbl1_Borealin_N PF10444.9 KPA46335.1 - 0.25 11.0 2.4 6.5 6.5 0.1 3.2 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal CLZ PF16526.5 KPA46335.1 - 0.71 10.3 4.7 13 6.2 0.3 3.2 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 KPA46335.1 - 2.2 8.6 10.3 6.4 7.1 0.9 4.2 4 0 0 4 4 4 0 ABC transporter C-terminal domain WD40 PF00400.32 KPA46336.1 - 9.9e-17 61.0 6.0 0.013 16.4 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPA46336.1 - 9.2e-07 29.1 0.2 4 7.8 0.0 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPA46336.1 - 0.25 10.3 0.0 2.6 6.9 0.0 2.6 3 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PHD PF00628.29 KPA46337.1 - 3.9e-11 42.7 6.9 9.3e-11 41.5 6.9 1.7 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KPA46337.1 - 0.13 12.6 0.2 0.46 10.9 0.2 1.9 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx zf-RING_2 PF13639.6 KPA46337.1 - 3.3 8.1 6.6 11 6.5 6.6 1.9 1 0 0 1 1 1 0 Ring finger domain SCO1-SenC PF02630.14 KPA46338.1 - 3.3e-48 163.0 0.0 4.5e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KPA46338.1 - 0.0032 17.4 0.0 0.0078 16.1 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPA46338.1 - 0.013 15.3 0.0 0.15 11.8 0.0 2.2 1 1 0 1 1 1 0 Redoxin Hydrolase_6 PF13344.6 KPA46339.1 - 3.5e-21 75.2 0.0 7.5e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA46339.1 - 4.1e-17 62.0 0.0 8.4e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KPA46339.1 - 0.00021 21.7 0.0 7.6 6.8 0.0 4.2 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase T5orf172 PF10544.9 KPA46340.1 - 7.6e-17 61.7 0.1 2.4e-16 60.2 0.1 1.9 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KPA46340.1 - 7.4e-08 33.0 0.2 3.5e-07 30.8 0.1 2.2 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 Choline_kinase PF01633.20 KPA46341.1 - 8.7e-60 201.9 0.3 1.9e-59 200.8 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KPA46341.1 - 1.2e-17 63.3 0.0 2.2e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 KPA46341.1 - 4.8e-05 23.4 0.5 0.00012 22.1 0.5 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4674 PF15719.5 KPA46341.1 - 0.23 11.5 5.5 0.63 10.1 5.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Macoilin PF09726.9 KPA46341.1 - 4.2 5.8 11.9 5.9 5.3 11.9 1.3 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 KPA46341.1 - 5.5 5.7 9.0 9.7 4.8 9.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BTB PF00651.31 KPA46342.1 - 1.9e-27 95.7 0.1 1.6e-13 50.8 0.3 3.2 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 KPA46342.1 - 5.1e-08 33.3 0.0 1.5e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA46342.1 - 6.1e-07 29.9 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KPA46342.1 - 3e-06 27.4 0.1 0.014 15.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KPA46342.1 - 1.3e-05 25.4 0.0 3.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA46342.1 - 2.9e-05 24.1 0.1 0.19 12.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat DHHC PF01529.20 KPA46343.1 - 6.6e-29 100.7 4.9 6.6e-29 100.7 4.9 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ni_hydr_CYTB PF01292.20 KPA46343.1 - 7.2 6.2 10.1 0.32 10.6 0.7 2.4 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF3185 PF11381.8 KPA46344.1 - 0.38 10.8 7.6 5.1 7.2 1.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Aha1_N PF09229.11 KPA46345.1 - 3.8e-41 140.5 0.6 5.9e-41 139.9 0.6 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KPA46345.1 - 2.3e-18 66.6 0.3 4.1e-18 65.8 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein SH3BGR PF04908.15 KPA46345.1 - 0.029 14.5 1.3 4 7.7 0.1 3.4 3 1 1 4 4 4 0 SH3-binding, glutamic acid-rich protein Complex1_LYR_2 PF13233.6 KPA46347.1 - 2.2e-21 76.4 0.0 2.7e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Inositol_P PF00459.25 KPA46348.1 - 1.9e-53 181.8 1.5 4.4e-53 180.5 1.5 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.23 KPA46349.1 - 8.6e-19 68.0 0.0 8.7e-09 35.9 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein L6 Med3 PF11593.8 KPA46349.1 - 5.1 6.2 5.7 7.1 5.7 5.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Tubulin PF00091.25 KPA46350.1 - 1.6e-68 230.8 0.0 5.9e-68 229.0 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KPA46350.1 - 1.3e-42 145.0 0.1 1.9e-42 144.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KPA46350.1 - 1.1e-05 25.7 0.0 5.8e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KPA46350.1 - 0.0033 17.1 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KPA46350.1 - 0.0049 16.1 0.0 0.024 13.8 0.0 1.9 2 0 0 2 2 2 1 Tubulin like TANGO2 PF05742.12 KPA46351.1 - 0.073 13.1 0.1 0.08 13.0 0.1 1.1 1 0 0 1 1 1 0 Transport and Golgi organisation 2 ABC_tran PF00005.27 KPA46352.1 - 2.2e-47 161.0 0.7 1.9e-22 80.2 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KPA46352.1 - 1e-19 70.3 7.3 1e-19 70.3 7.3 3.9 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 KPA46352.1 - 1.3e-17 64.6 0.9 0.0017 18.2 0.0 4.5 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPA46352.1 - 1.9e-09 37.3 6.9 0.0079 15.7 0.0 4.6 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KPA46352.1 - 9.4e-07 29.4 0.0 0.029 14.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KPA46352.1 - 1.7e-06 28.1 1.2 0.012 15.7 0.2 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KPA46352.1 - 1.9e-06 27.5 0.2 0.059 13.1 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KPA46352.1 - 5.6e-06 26.4 1.4 0.054 13.4 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_23 PF13476.6 KPA46352.1 - 7.1e-06 26.7 18.4 0.0054 17.3 0.0 4.7 5 0 0 5 5 5 2 AAA domain AAA_30 PF13604.6 KPA46352.1 - 1.6e-05 24.8 2.0 0.0098 15.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 KPA46352.1 - 1.6e-05 25.2 0.2 0.37 11.1 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KPA46352.1 - 4.9e-05 23.8 0.4 0.082 13.3 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KPA46352.1 - 6.9e-05 23.3 0.0 0.62 10.5 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KPA46352.1 - 0.00011 22.1 12.1 0.08 12.6 0.0 5.0 5 1 0 5 5 5 2 AAA ATPase domain AAA_24 PF13479.6 KPA46352.1 - 0.00012 21.9 1.1 0.99 9.1 0.1 3.9 4 0 0 4 4 4 2 AAA domain AAA_28 PF13521.6 KPA46352.1 - 0.00034 20.9 0.4 0.45 10.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPA46352.1 - 0.00039 20.6 1.4 1.2 9.3 0.1 3.2 3 1 0 3 3 2 2 AAA domain MeaB PF03308.16 KPA46352.1 - 0.0021 17.1 1.4 0.37 9.7 0.0 2.7 3 0 0 3 3 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KPA46352.1 - 0.003 17.8 1.1 1.5 9.1 0.0 3.0 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KPA46352.1 - 0.0038 17.3 0.0 2 8.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KPA46352.1 - 0.0042 16.7 1.4 3.8 7.1 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KPA46352.1 - 0.0044 16.5 0.0 2 7.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 KPA46352.1 - 0.005 16.5 0.5 1.3 8.6 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 KPA46352.1 - 0.0051 16.5 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 KPA46352.1 - 0.0055 16.6 0.4 3.8 7.4 0.0 2.8 2 0 0 2 2 2 1 NACHT domain MobB PF03205.14 KPA46352.1 - 0.0066 16.4 0.0 0.53 10.2 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KPA46352.1 - 0.0076 16.2 0.0 1.3 9.0 0.0 2.7 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KPA46352.1 - 0.011 16.1 0.0 7.4 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 KPA46352.1 - 0.015 15.3 0.2 3.9 7.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KPA46352.1 - 0.022 14.0 0.0 4.2 6.5 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 KPA46352.1 - 0.043 14.3 2.2 25 5.3 0.2 3.8 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KPA46352.1 - 0.065 13.2 0.0 9.6 6.2 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CHASE6_C PF17150.4 KPA46352.1 - 0.1 13.3 1.0 0.31 11.7 0.0 2.4 2 0 0 2 2 1 0 C-terminal domain of two-partite extracellular sensor domain Rad17 PF03215.15 KPA46352.1 - 0.21 11.5 1.7 9.4 6.1 0.0 3.2 2 1 1 3 3 3 0 Rad17 P-loop domain Thymidylate_kin PF02223.17 KPA46352.1 - 0.31 10.7 2.9 4.8 6.8 0.0 3.7 4 0 0 4 4 3 0 Thymidylate kinase DUF87 PF01935.17 KPA46352.1 - 0.94 9.5 9.0 2.9 7.9 0.0 4.0 4 0 0 4 4 4 0 Helicase HerA, central domain Zeta_toxin PF06414.12 KPA46352.1 - 1.8 7.8 7.1 5.1 6.3 0.1 3.8 4 0 0 4 4 4 0 Zeta toxin Dynamin_N PF00350.23 KPA46352.1 - 8.6 6.4 18.0 13 5.8 0.0 5.1 5 2 1 6 6 5 0 Dynamin family DUF4568 PF15132.6 KPA46353.1 - 0.044 13.2 0.1 0.087 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) Spermine_synth PF01564.17 KPA46355.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 KPA46355.1 - 2.4e-06 27.5 0.0 2e-05 24.5 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA46355.1 - 0.0027 18.4 0.0 0.0055 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA46355.1 - 0.017 15.8 0.0 0.03 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KPA46355.1 - 0.095 13.4 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 KPA46356.1 - 1.4e-22 80.0 0.0 2.7e-22 79.1 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA46356.1 - 0.064 13.4 5.3 0.12 12.5 5.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_10 PF13673.7 KPA46357.1 - 1.3e-10 41.3 0.0 1.9e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPA46357.1 - 5e-08 33.3 0.1 7.9e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA46357.1 - 2.9e-06 27.5 0.0 4.1e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KPA46357.1 - 7.4e-05 22.7 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KPA46357.1 - 0.00046 20.3 0.0 0.0017 18.5 0.0 2.0 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KPA46357.1 - 0.0016 18.5 0.1 0.0037 17.3 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Tyrosinase PF00264.20 KPA46358.1 - 2.1e-45 155.7 4.5 3.7e-45 154.9 4.5 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KPA46358.1 - 0.00057 20.5 0.1 0.0053 17.4 0.1 2.2 1 1 0 1 1 1 1 Tyosinase C-terminal domain DHDPS PF00701.22 KPA46359.1 - 3.8e-37 127.6 0.0 5.1e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family IU_nuc_hydro PF01156.19 KPA46359.1 - 0.009 15.6 0.3 0.16 11.5 0.0 2.0 2 0 0 2 2 2 1 Inosine-uridine preferring nucleoside hydrolase zf-primase PF09329.11 KPA46360.1 - 2.4e-17 62.5 2.2 4.5e-17 61.6 2.2 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 KPA46360.1 - 0.027 14.4 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RNase_H2-Ydr279 PF09468.10 KPA46361.1 - 6.1e-45 153.3 1.1 6.1e-45 153.3 1.1 2.6 2 1 1 3 3 3 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KPA46361.1 - 1.7e-24 85.9 0.0 4.8e-24 84.4 0.0 1.8 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain SSP160 PF06933.11 KPA46361.1 - 0.0095 14.2 5.3 0.013 13.7 5.3 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Latrophilin PF02354.16 KPA46361.1 - 0.12 11.4 4.8 0.02 14.0 0.8 1.6 2 0 0 2 2 2 0 Latrophilin Cytoplasmic C-terminal region DASH_Duo1 PF08651.10 KPA46362.1 - 2e-30 104.4 0.2 3.1e-30 103.8 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF1682 PF07946.14 KPA46362.1 - 0.063 12.5 5.4 0.081 12.1 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF2681 PF10883.8 KPA46362.1 - 1.4 9.4 6.1 2.4 8.6 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF3391 PF11871.8 KPA46362.1 - 1.9 9.0 7.9 9.1 6.8 4.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) FYVE_2 PF02318.16 KPA46362.1 - 2.3 8.4 5.8 4 7.7 5.8 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger TTL PF03133.15 KPA46364.1 - 1.4e-55 188.5 0.0 2.2e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KPA46364.1 - 5.3e-52 176.4 0.0 8.3e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KPA46364.1 - 0.00043 19.6 0.0 0.0012 18.1 0.0 1.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp Cation_ATPase_C PF00689.21 KPA46365.1 - 1.6e-43 148.5 6.0 1.6e-43 148.5 6.0 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KPA46365.1 - 6e-32 110.6 0.6 6e-32 110.6 0.6 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KPA46365.1 - 6.9e-22 77.3 0.0 1.4e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPA46365.1 - 1.7e-21 77.5 0.0 5.6e-21 75.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPA46365.1 - 3.5e-07 29.8 0.0 1.6e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPA46365.1 - 1.5e-06 28.2 1.3 9e-06 25.6 0.8 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPA46365.1 - 0.0082 16.6 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KPA46365.1 - 0.099 11.5 2.7 0.33 9.7 2.7 1.9 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF2976 PF11190.8 KPA46365.1 - 0.52 10.1 7.9 0.96 9.3 0.4 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) SIR2 PF02146.17 KPA46366.1 - 2.1e-59 200.4 0.0 3.2e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KPA46366.1 - 0.0004 20.1 0.3 0.36 10.6 0.1 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KPA46366.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Pkinase PF00069.25 KPA46367.1 - 2.8e-17 62.9 0.0 1.1e-16 61.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46367.1 - 2e-09 37.1 0.0 1.4e-08 34.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 KPA46367.1 - 0.019 14.6 0.2 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 Aminotran_4 PF01063.19 KPA46368.1 - 6.8e-35 120.9 0.0 8.6e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV ESSS PF10183.9 KPA46369.1 - 4.2e-07 30.1 0.0 5.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ArAE_2_N PF10337.9 KPA46370.1 - 1.7e-10 40.6 2.5 7.9e-07 28.5 0.3 3.3 2 1 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KPA46370.1 - 6.8e-09 35.9 31.5 1.4e-07 31.7 8.4 3.1 2 1 1 3 3 3 2 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KPA46370.1 - 5.3e-05 23.2 0.0 9.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 Dna2 PF08696.11 KPA46371.1 - 1.8e-69 233.7 0.1 5.3e-69 232.1 0.0 1.9 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 KPA46371.1 - 1.3e-52 178.3 0.0 2.7e-52 177.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPA46371.1 - 1.6e-31 110.0 2.2 7.8e-16 58.6 0.0 3.5 3 1 1 4 4 3 2 AAA domain AAA_30 PF13604.6 KPA46371.1 - 9.1e-17 61.4 0.0 2e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPA46371.1 - 8e-12 45.7 0.4 2.6e-11 44.0 0.0 2.2 2 0 0 2 2 1 1 AAA domain Cas_Cas4 PF01930.17 KPA46371.1 - 2.5e-09 37.4 0.1 6.3e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KPA46371.1 - 1e-05 25.4 3.6 0.54 10.0 0.1 3.9 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KPA46371.1 - 0.00012 21.9 0.0 0.00044 20.2 0.0 1.9 1 1 0 1 1 1 1 Helicase PIF1 PF05970.14 KPA46371.1 - 0.00058 19.1 0.0 0.072 12.3 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase SRP54 PF00448.22 KPA46371.1 - 0.0011 18.6 0.2 0.0023 17.6 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KPA46371.1 - 0.0014 19.0 0.0 0.0076 16.7 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KPA46371.1 - 0.0071 16.4 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KPA46371.1 - 0.0081 15.7 0.1 0.021 14.3 0.1 1.8 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain CbiA PF01656.23 KPA46371.1 - 0.0095 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 KPA46371.1 - 0.011 15.3 0.1 0.023 14.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MobB PF03205.14 KPA46371.1 - 0.012 15.5 0.2 0.033 14.1 0.2 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.9 KPA46371.1 - 0.02 14.2 0.0 0.048 12.9 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KPA46371.1 - 0.02 14.4 0.0 0.081 12.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KPA46371.1 - 0.036 14.1 0.2 0.32 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KPA46371.1 - 0.046 14.2 0.2 0.17 12.3 0.1 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KPA46371.1 - 0.048 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KPA46371.1 - 0.069 13.1 0.3 0.17 11.8 0.3 1.5 1 0 0 1 1 1 0 NTPase Csa1 PF06023.12 KPA46371.1 - 0.07 12.5 0.0 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 CRISPR-associated exonuclease Csa1 cobW PF02492.19 KPA46371.1 - 0.097 12.3 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KPA46371.1 - 0.12 11.3 0.0 0.31 10.0 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 KPA46371.1 - 0.13 12.0 0.1 0.36 10.6 0.1 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF87 PF01935.17 KPA46371.1 - 0.27 11.3 1.2 0.46 10.5 0.2 2.0 2 0 0 2 2 1 0 Helicase HerA, central domain DUF5123 PF17161.4 KPA46371.1 - 7.2 7.7 7.8 13 6.9 2.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5123) Aim21 PF11489.8 KPA46373.1 - 5.1e-174 581.1 93.3 5.1e-174 581.1 93.3 2.4 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 21 Cg6151-P PF10233.9 KPA46374.1 - 5.4e-41 139.4 14.5 6.4e-41 139.2 14.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P AgrB PF04647.15 KPA46374.1 - 0.11 11.8 12.6 0.15 11.4 12.6 1.2 1 0 0 1 1 1 0 Accessory gene regulator B COPI_assoc PF08507.10 KPA46374.1 - 0.58 10.2 15.7 1.3 9.1 15.6 1.6 1 1 0 1 1 1 0 COPI associated protein CbiQ PF02361.16 KPA46374.1 - 0.8 9.3 7.9 1.1 8.8 7.9 1.2 1 0 0 1 1 1 0 Cobalt transport protein Presenilin PF01080.17 KPA46374.1 - 2.6 6.7 8.5 3 6.5 8.5 1.1 1 0 0 1 1 1 0 Presenilin OCD_Mu_crystall PF02423.15 KPA46375.1 - 3.2e-12 46.0 0.1 4.1e-07 29.2 0.0 2.5 3 0 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Thiolase_N PF00108.23 KPA46376.1 - 1.6e-74 250.6 2.7 2.3e-74 250.0 2.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPA46376.1 - 8.9e-43 144.9 0.2 2e-42 143.7 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KPA46376.1 - 0.017 14.7 0.2 0.17 11.5 0.1 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KPA46376.1 - 0.079 13.1 0.0 0.27 11.4 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal YXWGXW PF12779.7 KPA46378.1 - 0.24 11.6 2.4 0.55 10.4 2.4 1.7 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) SelR PF01641.18 KPA46379.1 - 7.2e-49 164.9 0.0 9.1e-49 164.6 0.0 1.1 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 KPA46379.1 - 0.036 13.8 0.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 KPA46379.1 - 0.13 11.8 0.9 0.95 9.0 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Yippee-Mis18 PF03226.14 KPA46379.1 - 0.17 12.1 0.2 0.44 10.8 0.2 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 KPA46379.1 - 0.23 11.5 2.6 3.9 7.6 2.9 2.2 1 1 1 2 2 2 0 Double zinc ribbon ArfGap PF01412.18 KPA46380.1 - 1.5e-39 134.7 0.8 2.1e-39 134.2 0.8 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 KPA46380.1 - 0.12 12.1 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Synaptobrevin PF00957.21 KPA46381.1 - 0.015 15.1 0.4 0.18 11.6 0.1 2.0 1 1 1 2 2 2 0 Synaptobrevin Ysc84 PF04366.12 KPA46382.1 - 2.6e-41 140.4 0.2 4.3e-41 139.6 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KPA46382.1 - 9.3e-15 54.0 0.2 5.4e-14 51.5 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KPA46382.1 - 1.8e-13 50.1 0.0 3.7e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPA46382.1 - 1.1e-11 44.3 0.0 3.3e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 KPA46382.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) ARID PF01388.21 KPA46384.1 - 1.8e-17 63.8 0.1 7e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain NAAA-beta PF15508.6 KPA46384.1 - 0.068 13.5 0.1 1.8 8.9 0.0 2.8 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase adh_short_C2 PF13561.6 KPA46385.1 - 1.9e-64 217.4 0.5 1.9e-64 217.4 0.5 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA46385.1 - 7e-51 172.5 0.3 1.1e-50 171.8 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA46385.1 - 6.4e-11 42.5 0.3 9.5e-11 41.9 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPA46385.1 - 0.00013 21.6 0.2 0.00025 20.6 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPA46385.1 - 0.019 14.1 0.0 0.044 12.9 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KPA46385.1 - 0.064 14.0 0.1 0.16 12.7 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 KPA46387.1 - 5.5e-71 239.0 0.0 7.2e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46387.1 - 4.9e-45 153.8 0.0 7.7e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KPA46387.1 - 8e-19 67.8 0.0 2e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KPA46387.1 - 2.6e-07 30.2 0.5 4e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KPA46387.1 - 1.3e-06 27.5 0.0 2.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KPA46387.1 - 0.0076 15.6 0.1 0.077 12.3 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPA46387.1 - 0.025 14.5 0.7 0.26 11.2 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KPA46387.1 - 0.048 12.6 0.1 0.048 12.6 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain TFIIA PF03153.13 KPA46387.1 - 0.067 13.2 10.3 0.13 12.3 10.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KH_1 PF00013.29 KPA46388.1 - 8.3e-97 317.1 28.0 5.3e-14 51.8 0.1 14.5 15 2 0 15 15 15 9 KH domain KH_2 PF07650.17 KPA46388.1 - 1.2e-13 50.7 23.6 0.002 17.9 0.2 8.3 7 1 1 8 8 8 4 KH domain SLS PF14611.6 KPA46388.1 - 6.2e-11 42.6 6.9 0.0047 16.8 0.1 6.8 4 2 1 6 6 6 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 KPA46388.1 - 3.5e-05 23.6 8.5 0.12 12.2 0.1 5.9 6 0 0 6 6 6 2 KH domain BON PF04972.17 KPA46388.1 - 0.00029 21.1 2.3 1.3 9.4 0.0 4.5 3 0 0 3 3 3 2 BON domain KH_5 PF13184.6 KPA46388.1 - 0.0099 15.9 10.9 24 5.1 0.0 6.2 7 1 0 7 7 7 0 NusA-like KH domain DUF5300 PF17224.3 KPA46388.1 - 0.073 13.3 5.5 78 3.6 0.0 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF5300) AvrPto PF11592.8 KPA46388.1 - 0.085 12.9 0.2 7.1 6.7 0.1 3.5 3 0 0 3 3 3 0 Central core of the bacterial effector protein AvrPto BMC PF00936.19 KPA46388.1 - 0.13 12.2 0.5 25 5.0 0.0 4.5 5 0 0 5 5 5 0 BMC domain DUF211 PF02680.14 KPA46388.1 - 3.2 8.0 6.5 6.3 7.0 0.2 3.3 3 0 0 3 3 2 0 Uncharacterized ArCR, COG1888 YqgF PF14639.6 KPA46388.1 - 6.3 6.6 7.7 3.5 7.4 0.1 3.8 5 0 0 5 5 5 0 Holliday-junction resolvase-like of SPT6 adh_short PF00106.25 KPA46389.1 - 0.079 12.4 0.0 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.16 KPA46390.1 - 3.5e-21 75.5 38.6 4.9e-21 75.0 34.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_2 PF00002.24 KPA46390.1 - 0.03 13.6 0.5 0.81 8.9 0.1 2.5 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) UCR_hinge PF02320.16 KPA46391.1 - 1.7e-27 95.4 10.5 1.7e-27 95.4 10.5 1.8 2 0 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Mpp10 PF04006.12 KPA46391.1 - 0.044 12.2 18.3 0.048 12.1 18.3 1.0 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.12 KPA46391.1 - 0.067 13.0 12.0 0.082 12.7 12.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BUD22 PF09073.10 KPA46391.1 - 0.11 11.8 14.4 0.12 11.7 14.4 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KPA46391.1 - 0.35 9.0 19.1 0.37 8.9 19.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 KPA46391.1 - 0.48 9.3 5.7 0.53 9.2 5.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 KPA46391.1 - 0.49 8.6 12.6 0.51 8.6 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3391 PF11871.8 KPA46391.1 - 1.2 9.7 10.7 1.9 9.0 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) GET2 PF08690.10 KPA46391.1 - 1.3 8.6 6.8 1.6 8.4 6.8 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 DNA_pol_phi PF04931.13 KPA46391.1 - 1.4 6.9 24.2 1.7 6.7 24.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Cytomega_UL84 PF06284.11 KPA46391.1 - 1.6 7.1 12.1 1.7 7.0 12.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CPSF100_C PF13299.6 KPA46391.1 - 1.7 8.8 7.8 2.1 8.5 7.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Neur_chan_memb PF02932.16 KPA46391.1 - 1.7 8.6 4.4 1.9 8.5 4.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1115 PF06544.12 KPA46391.1 - 1.8 8.7 7.5 2.2 8.3 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) DUF2722 PF10846.8 KPA46391.1 - 1.9 7.4 10.5 2.2 7.1 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SAPS PF04499.15 KPA46391.1 - 2 7.1 7.0 2.2 7.0 7.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 KPA46391.1 - 2 7.7 18.7 2.3 7.5 18.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.6 KPA46391.1 - 2.1 8.8 10.1 3 8.3 10.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SDA1 PF05285.12 KPA46391.1 - 2.3 7.6 19.6 2.6 7.4 19.6 1.1 1 0 0 1 1 1 0 SDA1 SpoIIP PF07454.11 KPA46391.1 - 2.3 7.6 9.9 2.6 7.4 9.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TLP-20 PF06088.11 KPA46391.1 - 2.6 7.9 7.2 3.9 7.3 7.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Presenilin PF01080.17 KPA46391.1 - 2.8 6.6 9.1 3.2 6.4 9.1 1.0 1 0 0 1 1 1 0 Presenilin RPN2_C PF18004.1 KPA46391.1 - 3.3 7.6 13.1 4.1 7.3 13.1 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TRAP_alpha PF03896.16 KPA46391.1 - 4.2 6.5 12.4 4.9 6.3 12.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Astro_capsid_p PF12226.8 KPA46391.1 - 5.1 6.2 17.5 6.5 5.8 17.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CLN3 PF02487.17 KPA46391.1 - 5.2 6.0 4.0 6.2 5.8 4.0 1.1 1 0 0 1 1 1 0 CLN3 protein HSP70 PF00012.20 KPA46391.1 - 6.4 4.8 9.3 6.5 4.8 9.3 1.0 1 0 0 1 1 1 0 Hsp70 protein RRN3 PF05327.11 KPA46391.1 - 6.4 5.2 10.9 6.8 5.1 10.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Hid1 PF12722.7 KPA46391.1 - 7.9 4.5 6.9 8.6 4.3 6.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tim54 PF11711.8 KPA46391.1 - 8.5 5.0 13.0 9.5 4.9 13.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sporozoite_P67 PF05642.11 KPA46391.1 - 8.7 4.3 12.7 9.9 4.1 12.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Vps36_ESCRT-II PF11605.8 KPA46392.1 - 0.042 14.0 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 KPA46392.1 - 0.097 13.0 0.0 0.21 12.0 0.0 1.5 1 1 0 1 1 1 0 Bacterial PH domain RraA-like PF03737.15 KPA46393.1 - 6.4e-24 84.8 0.2 8.6e-24 84.4 0.2 1.2 1 0 0 1 1 1 1 Aldolase/RraA tRNA_bind_3 PF17176.4 KPA46393.1 - 0.0019 18.5 0.2 0.0057 16.9 0.1 1.6 1 1 0 1 1 1 1 tRNA-binding domain Drf_GBD PF06371.13 KPA46394.1 - 3e-14 53.0 2.3 3.8e-13 49.4 2.3 2.1 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Lactonase PF10282.9 KPA46395.1 - 5.7e-19 68.6 0.0 7.4e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF21 PF01595.20 KPA46396.1 - 3.2e-31 108.4 0.3 6.7e-31 107.3 0.3 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KPA46396.1 - 3.7e-07 30.5 0.6 0.015 15.8 0.1 3.7 3 0 0 3 3 3 2 CBS domain 2-Hacid_dh_C PF02826.19 KPA46397.1 - 1.7e-53 180.6 0.1 2.6e-53 180.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPA46397.1 - 6.1e-35 119.8 0.2 4.1e-34 117.1 0.1 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KPA46397.1 - 0.0005 19.8 0.1 0.0064 16.2 0.0 2.5 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.21 KPA46397.1 - 0.0012 19.0 0.2 0.0026 17.9 0.2 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 KPA46397.1 - 0.0024 17.2 0.4 0.0051 16.1 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Prot_ATP_OB_N PF17758.1 KPA46397.1 - 0.057 13.1 0.6 0.32 10.7 0.3 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain XdhC_C PF13478.6 KPA46397.1 - 0.058 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Glyoxalase PF00903.25 KPA46398.1 - 4.4e-37 127.1 0.1 4.8e-18 65.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KPA46398.1 - 8.7e-15 54.9 0.0 7.5e-06 26.2 0.0 3.6 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KPA46398.1 - 5.4e-06 27.2 0.0 0.029 15.1 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KPA46398.1 - 7.7e-06 26.1 0.0 0.026 14.7 0.0 2.9 1 1 3 4 4 4 4 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KPA46398.1 - 2.8e-05 24.0 1.2 3 7.8 0.0 4.5 4 1 1 5 5 5 3 Glyoxalase-like domain MoaF PF10703.9 KPA46398.1 - 0.011 15.6 0.0 0.72 9.8 0.0 2.4 2 0 0 2 2 2 0 MoaF N-terminal domain Pkinase PF00069.25 KPA46401.1 - 2.7e-06 27.0 0.0 0.22 10.8 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain SSB PF00436.25 KPA46401.1 - 0.066 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Single-strand binding protein family KCH PF16944.5 KPA46402.1 - 2.2e-100 335.6 10.1 2.6e-100 335.3 10.1 1.1 1 0 0 1 1 1 1 Fungal potassium channel PDEase_I PF00233.19 KPA46403.1 - 5.8e-68 229.2 0.0 8.7e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase UCH PF00443.29 KPA46404.1 - 4.6e-66 222.9 0.0 6.7e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KPA46404.1 - 3.7e-11 43.5 0.0 9.3e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 KPA46404.1 - 1.2e-08 35.0 0.0 0.00046 19.9 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-ribbon_3 PF13248.6 KPA46404.1 - 0.24 10.9 1.1 3 7.4 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_M16_M PF16187.5 KPA46405.1 - 1.4e-98 329.6 0.9 2.3e-98 329.0 0.9 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KPA46405.1 - 1.3e-33 116.1 0.0 6e-33 113.9 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KPA46405.1 - 3.3e-26 92.4 0.0 1.6e-15 57.6 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain FANC_SAP PF18081.1 KPA46405.1 - 0.0014 18.7 0.1 0.0043 17.2 0.1 1.8 1 0 0 1 1 1 1 Fanconi anemia-associated nuclease SAP domain MPP6 PF10175.9 KPA46406.1 - 4.9e-09 36.8 12.3 7.2e-07 29.8 12.2 2.4 1 1 0 1 1 1 1 M-phase phosphoprotein 6 zf-CCHC PF00098.23 KPA46406.1 - 0.00037 20.5 2.6 0.00058 19.8 2.6 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF2870 PF11069.8 KPA46406.1 - 0.24 11.8 3.3 7 7.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) zf-CHCC PF10276.9 KPA46407.1 - 1.3e-15 57.1 0.8 2.1e-15 56.5 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain UPF0047 PF01894.17 KPA46408.1 - 5e-38 129.8 0.0 5.7e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 NUDIX_2 PF13869.6 KPA46409.1 - 1.3e-80 269.4 0.0 1.6e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Pet100 PF09803.9 KPA46411.1 - 3.4e-18 65.9 0.2 4.3e-18 65.6 0.2 1.1 1 0 0 1 1 1 1 Pet100 ATPase_gene1 PF09527.10 KPA46411.1 - 0.064 13.4 0.3 0.084 13.1 0.3 1.1 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Transcrip_reg PF01709.20 KPA46412.1 - 2.2e-64 217.2 0.5 2.6e-64 217.0 0.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator TelA PF05816.11 KPA46412.1 - 0.013 14.6 0.4 0.063 12.3 0.2 2.1 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) HEAT_2 PF13646.6 KPA46413.1 - 3.1e-09 37.1 1.7 0.074 13.5 0.0 7.3 7 0 0 7 7 7 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KPA46413.1 - 5.3e-05 23.7 0.0 0.21 12.2 0.0 4.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KPA46413.1 - 5.6e-05 23.0 10.5 1.7 9.1 0.0 7.5 9 0 0 9 9 9 2 HEAT repeat CLASP_N PF12348.8 KPA46413.1 - 0.0002 21.0 0.4 26 4.3 0.0 5.4 4 1 1 5 5 5 0 CLASP N terminal IFRD PF05004.13 KPA46413.1 - 0.0012 18.0 9.9 0.0025 17.0 0.2 5.6 6 1 1 7 7 7 1 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 KPA46413.1 - 0.019 14.9 5.2 0.051 13.5 0.0 4.3 6 0 0 6 6 6 0 Myosin-binding striated muscle assembly central gpUL132 PF11359.8 KPA46413.1 - 0.047 13.2 0.1 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Glycoprotein UL132 HEAT_EZ PF13513.6 KPA46413.1 - 0.087 13.4 11.2 30 5.2 0.0 7.6 7 0 0 7 7 7 0 HEAT-like repeat Arm PF00514.23 KPA46413.1 - 0.25 11.5 1.2 55 4.0 0.3 4.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat RRM_1 PF00076.22 KPA46414.1 - 4.8e-09 35.9 0.0 0.0038 17.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PD40 PF07676.12 KPA46415.1 - 0.088 12.8 0.6 4.7 7.3 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KPA46415.1 - 0.091 10.7 0.0 0.85 7.5 0.0 2.1 3 0 0 3 3 3 0 IKI3 family SmaI PF17411.2 KPA46415.1 - 0.23 10.6 0.0 0.39 9.8 0.0 1.2 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease Mob_synth_C PF06463.13 KPA46416.1 - 7.2e-38 129.4 0.1 7.8e-37 126.1 0.0 2.1 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KPA46416.1 - 8.7e-25 88.0 0.1 2.7e-24 86.4 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KPA46416.1 - 4.8e-06 26.9 0.0 1.7e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KPA46416.1 - 0.036 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain MoaC PF01967.21 KPA46417.1 - 6.3e-55 185.0 3.2 7.8e-55 184.7 3.2 1.1 1 0 0 1 1 1 1 MoaC family FYVE PF01363.21 KPA46418.1 - 2.1e-14 53.4 12.2 4.1e-14 52.5 12.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KPA46418.1 - 3.8 7.7 19.4 0.044 13.9 9.2 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger ELO PF01151.18 KPA46419.1 - 1.8e-78 263.6 9.8 2.2e-78 263.2 9.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_S10 PF00450.22 KPA46420.1 - 2.5e-132 442.3 1.0 3.2e-132 441.9 1.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KPA46420.1 - 1.4e-16 61.1 4.9 5.7e-15 56.0 4.9 2.4 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide SBDS_C PF09377.10 KPA46421.1 - 1.6e-45 153.9 0.0 2.4e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KPA46421.1 - 4.4e-35 119.6 0.1 8.2e-35 118.8 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_S13 PF00416.22 KPA46422.1 - 4.1e-56 188.9 3.1 4.7e-56 188.7 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KPA46422.1 - 0.012 14.4 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KPA46422.1 - 0.1 12.9 0.1 0.41 10.9 0.0 2.0 1 1 1 2 2 2 0 Helix-hairpin-helix motif PP28 PF10252.9 KPA46422.1 - 0.14 12.6 0.3 0.34 11.4 0.3 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 DUF2989 PF11207.8 KPA46424.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) MFS_2 PF13347.6 KPA46426.1 - 1.8e-10 40.0 4.2 1.8e-10 40.0 4.2 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.16 KPA46426.1 - 1.3e-07 30.9 27.0 2.2e-07 30.2 21.6 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily S1FA PF04689.13 KPA46426.1 - 0.28 11.3 1.0 24 5.2 0.1 3.2 3 0 0 3 3 3 0 DNA binding protein S1FA MAPEG PF01124.18 KPA46428.1 - 4.6e-15 55.7 2.6 5.5e-15 55.4 2.6 1.1 1 0 0 1 1 1 1 MAPEG family Glyco_transf_34 PF05637.12 KPA46430.1 - 1.2e-65 221.6 0.5 1.6e-65 221.2 0.5 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Imm17 PF15562.6 KPA46431.1 - 0.68 9.8 9.7 0.87 9.5 2.3 3.1 3 0 0 3 3 3 0 Immunity protein 17 Peptidase_M22 PF00814.25 KPA46432.1 - 3.1e-46 158.3 0.2 3.4e-44 151.6 0.2 3.2 1 1 0 1 1 1 1 Glycoprotease family Proteasome PF00227.26 KPA46433.1 - 3e-47 160.6 0.4 3.5e-47 160.4 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit C2 PF00168.30 KPA46434.1 - 1.1e-85 282.6 0.1 9.1e-24 83.7 0.0 5.4 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 KPA46434.1 - 0.00086 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain UvrD-helicase PF00580.21 KPA46435.1 - 2.7e-09 37.0 0.0 5.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KPA46435.1 - 1.1e-05 25.1 0.0 2.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KPA46435.1 - 9.8e-05 22.7 0.0 0.0053 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KPA46435.1 - 0.012 15.4 0.0 1.8 8.2 0.0 2.5 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KPA46435.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain UvrD_C PF13361.6 KPA46435.1 - 0.026 13.9 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PRY PF13765.6 KPA46435.1 - 0.085 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 SPRY-associated domain FYVE PF01363.21 KPA46436.1 - 2.3e-21 75.7 2.0 2.3e-21 75.7 2.0 3.3 4 0 0 4 4 4 1 FYVE zinc finger zf-RING_2 PF13639.6 KPA46436.1 - 7.6e-07 29.4 5.1 7.6e-07 29.4 5.1 4.1 4 0 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 KPA46436.1 - 0.00026 20.7 4.0 0.00026 20.7 4.0 3.0 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KPA46436.1 - 0.00058 19.7 4.4 0.00058 19.7 4.4 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA46436.1 - 0.0027 17.7 5.9 0.0027 17.7 5.9 3.8 3 0 0 3 3 3 1 RING-type zinc-finger FYVE_2 PF02318.16 KPA46436.1 - 0.0046 17.2 1.8 0.0046 17.2 1.8 2.7 3 0 0 3 3 3 1 FYVE-type zinc finger zf-RING-like PF08746.11 KPA46436.1 - 0.006 16.9 2.4 0.006 16.9 2.4 2.8 2 0 0 2 2 1 1 RING-like domain zf-piccolo PF05715.13 KPA46436.1 - 0.034 14.3 14.0 0.085 13.0 5.4 3.1 3 0 0 3 3 3 0 Piccolo Zn-finger Rad50_zn_hook PF04423.14 KPA46436.1 - 0.04 13.8 2.2 0.15 11.9 0.4 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif DZR PF12773.7 KPA46436.1 - 0.14 12.2 7.7 2.5 8.2 5.0 3.0 2 0 0 2 2 2 0 Double zinc ribbon Elf1 PF05129.13 KPA46436.1 - 1.4 9.0 11.1 4.4 7.4 2.4 3.8 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like IBR PF01485.21 KPA46436.1 - 5.5 7.3 11.3 0.47 10.7 4.7 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Cupin_2 PF07883.11 KPA46437.1 - 7.6e-07 28.8 0.1 2.6e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KPA46437.1 - 0.00017 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KPA46437.1 - 0.054 13.2 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_1 PF00190.22 KPA46437.1 - 0.086 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Cupin Fungal_trans PF04082.18 KPA46438.1 - 6.3e-08 32.0 0.0 2e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPA46438.1 - 7.5e-08 32.4 14.3 2.4e-05 24.5 3.3 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KPA46438.1 - 1e-06 28.8 10.1 1e-06 28.8 10.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KPA46438.1 - 4.9e-06 26.9 12.9 0.00064 20.4 2.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPA46438.1 - 0.018 15.5 0.4 0.018 15.5 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 KPA46438.1 - 0.044 13.8 3.7 0.38 10.8 0.6 2.5 1 1 1 2 2 2 0 BED zinc finger zf-met PF12874.7 KPA46438.1 - 0.052 14.0 0.9 11 6.6 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KPA46438.1 - 0.076 13.3 1.2 0.3 11.4 1.2 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KPA46438.1 - 0.56 10.6 5.7 11 6.4 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Hydrolase_4 PF12146.8 KPA46439.1 - 1.2e-12 47.6 0.2 2e-12 46.9 0.2 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPA46439.1 - 2.3e-10 41.5 6.2 3.2e-10 41.0 6.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA46439.1 - 2.7e-09 37.0 0.1 5.7e-09 36.0 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold UPF0227 PF05728.12 KPA46439.1 - 0.12 12.3 0.1 4.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 KPA46439.1 - 0.16 12.1 0.1 1 9.4 0.1 2.0 2 0 0 2 2 2 0 Thioesterase domain ABC_membrane PF00664.23 KPA46440.1 - 2.6e-83 279.8 37.3 2.8e-44 151.8 14.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA46440.1 - 1.1e-62 210.6 0.0 2.8e-31 108.9 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPA46440.1 - 2.9e-14 53.0 6.0 1.6e-06 27.7 0.7 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KPA46440.1 - 1e-08 35.8 1.0 0.002 18.5 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KPA46440.1 - 2e-06 28.1 1.5 0.15 12.4 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KPA46440.1 - 3.3e-06 26.7 0.3 0.0099 15.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KPA46440.1 - 5.6e-06 26.4 0.2 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KPA46440.1 - 8.6e-06 24.8 1.4 0.045 12.5 0.0 3.7 5 0 0 5 5 5 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 KPA46440.1 - 3.9e-05 23.5 0.1 0.044 13.5 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KPA46440.1 - 6.2e-05 23.0 4.1 1.8 8.3 0.1 3.6 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KPA46440.1 - 6.6e-05 22.7 0.4 0.3 10.8 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 KPA46440.1 - 0.00012 22.5 1.3 12 6.3 0.1 4.5 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KPA46440.1 - 0.00089 18.9 0.6 0.97 9.0 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_5 PF07728.14 KPA46440.1 - 0.0016 18.4 0.1 1.2 9.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KPA46440.1 - 0.0069 16.9 2.6 0.33 11.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KPA46440.1 - 0.015 15.1 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rad17 PF03215.15 KPA46440.1 - 0.016 15.1 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 KPA46440.1 - 0.022 14.8 0.1 5.1 7.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain ATPase_2 PF01637.18 KPA46440.1 - 0.027 14.4 0.2 0.39 10.6 0.1 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KPA46440.1 - 0.036 13.6 0.1 8.3 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 KPA46440.1 - 0.045 13.5 0.0 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain S_4TM PF18159.1 KPA46440.1 - 0.055 12.8 0.1 0.055 12.8 0.1 2.8 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain AAA_33 PF13671.6 KPA46440.1 - 0.06 13.5 0.1 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KPA46440.1 - 0.063 13.0 0.0 10 5.8 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 KPA46440.1 - 0.077 12.6 0.0 17 4.9 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KPA46440.1 - 0.14 11.4 0.0 17 4.5 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 KPA46440.1 - 0.15 12.6 0.0 9.5 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KPA46440.1 - 0.19 12.0 5.4 4.3 7.6 0.4 3.9 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit tRNA-synt_His PF13393.6 KPA46441.1 - 1.8e-40 139.2 0.0 4.2e-34 118.2 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KPA46441.1 - 2.1e-13 50.2 0.0 4.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KPA46441.1 - 2.8e-05 23.8 0.0 5.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 KPA46441.1 - 0.017 14.2 0.1 0.067 12.3 0.1 2.2 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) Rac1 PF09632.10 KPA46441.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Rac1-binding domain NPBW PF15180.6 KPA46442.1 - 0.075 12.9 0.9 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 Neuropeptides B and W Pkinase PF00069.25 KPA46443.1 - 2.7e-67 226.9 0.1 5.4e-67 225.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46443.1 - 3.1e-33 115.1 0.0 5.3e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA46443.1 - 0.0001 21.7 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KPA46443.1 - 0.00062 18.7 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KPA46443.1 - 0.0054 16.3 0.1 0.48 9.9 0.0 2.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.14 KPA46443.1 - 0.0087 15.4 0.1 0.024 14.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Foamy_BEL PF03274.14 KPA46443.1 - 0.079 12.3 0.2 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Foamy virus BEL 1/2 protein UQ_con PF00179.26 KPA46444.1 - 7.7e-26 90.4 0.0 8.9e-26 90.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPA46444.1 - 5.9e-06 26.0 0.0 7.2e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KPA46444.1 - 0.00025 20.9 0.1 0.00033 20.5 0.1 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KPA46444.1 - 0.0014 18.9 0.0 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.11 KPA46444.1 - 0.066 12.8 0.0 0.098 12.3 0.0 1.3 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Sec1 PF00995.23 KPA46445.1 - 1.2e-129 434.2 0.0 1.3e-129 434.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Transposase_22 PF02994.14 KPA46445.1 - 0.01 16.0 0.0 0.16 12.2 0.1 2.7 2 0 0 2 2 2 0 L1 transposable element RBD-like domain DGCR6 PF07324.11 KPA46445.1 - 0.16 11.6 2.7 0.19 11.3 0.4 2.3 3 0 0 3 3 3 0 DiGeorge syndrome critical region 6 (DGCR6) protein UPF0014 PF03649.13 KPA46445.1 - 0.23 10.8 0.2 1 8.7 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0014) Amino_oxidase PF01593.24 KPA46446.1 - 1.6e-85 288.1 0.2 8.5e-73 246.2 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KPA46446.1 - 3.7e-12 46.4 0.0 1.2e-11 44.7 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 KPA46446.1 - 3.3e-07 30.4 0.0 7.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 KPA46446.1 - 3.7e-06 27.3 9.2 6.4e-06 26.5 2.3 2.9 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KPA46446.1 - 7e-05 23.3 2.5 8.3e-05 23.1 1.1 1.9 1 1 0 1 1 1 1 HMG-box domain DAO PF01266.24 KPA46446.1 - 0.00048 19.8 0.1 0.0012 18.5 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPA46446.1 - 0.01 15.1 0.1 0.03 13.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ATP-synt PF00231.19 KPA46447.1 - 2.4e-80 270.3 2.7 2.9e-80 270.0 2.7 1.0 1 0 0 1 1 1 1 ATP synthase DUF1678 PF07913.11 KPA46447.1 - 0.09 12.5 0.0 1.4 8.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1678) Topoisom_I PF01028.20 KPA46448.1 - 2.7e-95 318.1 4.5 2.7e-95 318.1 4.5 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KPA46448.1 - 2.6e-91 304.9 6.9 2.6e-91 304.9 6.9 3.7 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KPA46448.1 - 3.9e-32 110.0 0.4 3.9e-32 110.0 0.4 2.5 2 0 0 2 2 2 1 C-terminal topoisomerase domain LigA PF07746.11 KPA46448.1 - 0.0073 16.4 0.0 0.05 13.8 0.0 2.5 2 0 0 2 2 2 1 Aromatic-ring-opening dioxygenase LigAB, LigA subunit Glyco_hydro_16 PF00722.21 KPA46449.1 - 3.2e-43 147.3 1.3 5.2e-43 146.6 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-C2H2 PF00096.26 KPA46450.1 - 8.5e-13 48.0 11.0 2.4e-06 27.7 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA46450.1 - 5e-08 33.1 8.9 0.0028 18.4 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPA46450.1 - 6.3e-08 32.7 12.0 2.5e-07 30.8 4.5 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KPA46450.1 - 2e-06 28.0 3.9 0.00037 20.8 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KPA46450.1 - 9.1e-06 25.8 3.5 0.0044 17.3 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KPA46450.1 - 4.6e-05 23.3 8.3 0.0079 16.2 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KPA46450.1 - 0.018 14.7 3.0 1.8 8.3 0.1 2.6 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 KPA46450.1 - 0.066 13.2 5.1 0.035 14.1 1.5 2.3 1 1 1 2 2 2 0 BED zinc finger zf_UBZ PF18439.1 KPA46450.1 - 0.074 12.7 1.6 3.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KPA46450.1 - 0.62 9.9 5.4 11 5.9 0.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KPA46450.1 - 2.4 8.3 4.7 12 6.1 0.6 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-CHY PF05495.12 KPA46450.1 - 8.6 6.9 8.2 4.5 7.8 2.8 2.4 2 0 0 2 2 2 0 CHY zinc finger Diphthami_syn_2 PF01902.17 KPA46451.1 - 7.4e-23 81.2 0.0 3.1e-17 62.8 0.0 3.3 2 1 1 3 3 3 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KPA46451.1 - 3.8e-09 36.6 0.1 2.3e-05 24.4 0.0 3.5 3 0 0 3 3 3 2 Endoribonuclease L-PSP Aldo_ket_red PF00248.21 KPA46452.1 - 3.6e-53 180.7 0.0 4e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L35p PF01632.19 KPA46452.1 - 0.35 11.4 0.8 0.79 10.3 0.8 1.5 1 0 0 1 1 1 0 Ribosomal protein L35 AAA_11 PF13086.6 KPA46453.1 - 2.3e-59 201.3 0.2 1.8e-58 198.4 0.3 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KPA46453.1 - 6.1e-49 166.4 0.0 2.1e-48 164.6 0.0 1.9 3 0 0 3 3 2 1 AAA domain DUF202 PF02656.15 KPA46453.1 - 1.6e-20 73.3 1.4 2.1e-20 72.9 0.4 1.8 2 0 0 2 2 1 1 Domain of unknown function (DUF202) AAA_30 PF13604.6 KPA46453.1 - 1e-11 44.9 0.0 2e-10 40.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPA46453.1 - 1.3e-08 35.2 0.0 4.2e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KPA46453.1 - 6.2e-07 29.0 0.1 2.7e-06 26.9 0.1 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KPA46453.1 - 4e-06 26.9 0.0 1.2e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KPA46453.1 - 4.5e-05 23.1 0.0 0.00038 20.1 0.1 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KPA46453.1 - 0.00048 19.9 0.0 0.47 10.1 0.0 2.7 3 0 0 3 3 2 2 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KPA46453.1 - 0.0028 16.8 0.0 0.0062 15.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Helicase_RecD PF05127.14 KPA46453.1 - 0.003 17.5 0.0 0.066 13.1 0.0 2.6 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.6 KPA46453.1 - 0.0047 17.3 0.1 0.015 15.7 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KPA46453.1 - 0.0049 16.5 0.3 0.19 11.3 0.0 3.3 3 1 1 4 4 4 1 AAA domain AAA_22 PF13401.6 KPA46453.1 - 0.0059 16.9 0.2 0.047 13.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KPA46453.1 - 0.023 14.4 0.0 0.11 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KPA46453.1 - 0.025 15.0 0.2 0.13 12.6 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KPA46453.1 - 0.025 14.0 0.0 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein 4HB_MCP_1 PF12729.7 KPA46453.1 - 0.054 13.0 0.5 0.16 11.5 0.5 1.7 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Flavi_DEAD PF07652.14 KPA46453.1 - 0.055 13.4 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain ParA PF10609.9 KPA46453.1 - 0.074 12.5 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase IstB_IS21 PF01695.17 KPA46453.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein XhlA PF10779.9 KPA46454.1 - 0.038 14.2 0.3 0.4 10.9 0.0 2.4 2 0 0 2 2 2 0 Haemolysin XhlA MbeD_MobD PF04899.12 KPA46454.1 - 0.11 12.6 0.7 15 5.8 0.1 2.5 2 0 0 2 2 2 0 MbeD/MobD like Peptidase_M3 PF01432.20 KPA46455.1 - 3.3e-118 395.9 0.0 6.4e-118 394.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KPA46455.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like PA28_beta PF02252.18 KPA46455.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit ApoO PF09769.9 KPA46456.1 - 4.3e-42 143.2 2.1 1.2e-41 141.7 0.1 2.3 3 0 0 3 3 3 1 Apolipoprotein O Dus PF01207.17 KPA46457.1 - 1.2e-45 156.0 0.0 8.6e-45 153.2 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxysterol_BP PF01237.18 KPA46459.1 - 6.3e-91 305.0 0.1 8.1e-80 268.4 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein zf-CCCH PF00642.24 KPA46460.1 - 1.2e-08 34.6 18.6 5.3e-07 29.4 2.6 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KPA46460.1 - 0.0041 16.9 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KPA46460.1 - 0.0072 17.0 3.2 0.4 11.4 0.2 2.5 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KPA46460.1 - 0.012 15.6 2.9 0.012 15.6 2.9 3.3 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 KPA46460.1 - 0.17 12.1 3.7 0.37 11.0 0.1 2.5 2 1 0 2 2 2 0 Zinc-finger containing family ELMO_CED12 PF04727.13 KPA46461.1 - 3.7e-49 167.2 0.0 6e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KPA46461.1 - 5.5e-41 140.2 0.0 9.5e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KPA46461.1 - 1.2e-14 54.5 0.0 3.3e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) PRA1 PF03208.19 KPA46462.1 - 3.1e-34 117.6 1.5 4.9e-34 117.0 1.5 1.2 1 0 0 1 1 1 1 PRA1 family protein Renin_r PF07850.14 KPA46462.1 - 2 9.1 7.6 0.19 12.3 0.4 2.7 2 1 0 2 2 2 0 Renin receptor-like protein Spt5_N PF11942.8 KPA46462.1 - 8.1 7.5 21.9 21 6.2 1.3 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal UQ_con PF00179.26 KPA46463.1 - 2.4e-31 108.2 0.0 3e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_E PF14462.6 KPA46463.1 - 0.012 15.4 0.0 0.049 13.4 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic E2 family E BphX PF06139.12 KPA46463.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 BphX-like Prok-E2_B PF14461.6 KPA46463.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KPA46463.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 UEV domain Anp1 PF03452.14 KPA46464.1 - 4.2e-108 360.7 0.0 5e-108 360.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KPA46464.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Cmyb_C PF09316.10 KPA46464.1 - 0.12 12.0 0.2 3.5 7.3 0.0 2.2 2 0 0 2 2 2 0 C-myb, C-terminal RRM_1 PF00076.22 KPA46465.1 - 1.3e-18 66.6 0.0 2.3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KPA46465.1 - 6.4e-06 26.6 16.9 6.4e-06 26.6 16.9 3.9 3 2 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 RRM_3 PF08777.11 KPA46465.1 - 0.075 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif RHH_7 PF16777.5 KPA46466.1 - 0.41 11.1 0.1 0.41 11.1 0.1 1.8 2 0 0 2 2 2 0 Transcriptional regulator, RHH-like, CopG Ank_2 PF12796.7 KPA46467.1 - 1.5e-47 160.1 10.3 1.1e-12 48.3 0.1 9.3 3 2 8 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA46467.1 - 1e-43 147.1 10.0 1.3e-08 35.2 0.0 11.3 8 3 4 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA46467.1 - 2.6e-41 134.8 13.8 0.0044 17.4 0.0 15.6 17 0 0 17 17 17 10 Ankyrin repeat Ank PF00023.30 KPA46467.1 - 4.4e-29 99.6 22.5 0.014 15.8 0.0 13.8 12 2 2 14 14 14 9 Ankyrin repeat Ank_5 PF13857.6 KPA46467.1 - 2e-16 59.8 15.6 0.0036 17.6 0.1 9.8 6 2 4 10 10 10 6 Ankyrin repeats (many copies) DUF1932 PF09130.11 KPA46468.1 - 5.4e-25 87.2 0.0 9.9e-25 86.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KPA46468.1 - 1.4e-06 28.5 0.0 2.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KPA46468.1 - 1.8e-06 28.4 0.2 3.6e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Porph_ging PF09697.10 KPA46468.1 - 0.095 13.3 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) tRNA-synt_1 PF00133.22 KPA46470.1 - 9.4e-221 734.2 0.3 1.6e-219 730.2 0.3 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KPA46470.1 - 3.1e-34 118.1 3.0 1.1e-33 116.4 3.0 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KPA46470.1 - 1.9e-13 50.0 0.3 2.5e-06 26.5 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KPA46470.1 - 5.9e-12 45.5 0.0 7e-09 35.5 0.0 2.8 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 KPA46470.1 - 2.9e-07 30.7 5.1 2.9e-07 30.7 5.1 2.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm Fusion_gly PF00523.18 KPA46470.1 - 0.08 11.2 0.0 0.14 10.4 0.0 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 DEAD PF00270.29 KPA46471.1 - 1.7e-47 161.4 0.0 4.6e-47 160.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA46471.1 - 2.2e-28 98.8 0.0 1.4e-27 96.3 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA46471.1 - 0.00055 20.0 0.0 0.0017 18.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 KPA46471.1 - 0.0025 18.3 2.7 0.0025 18.3 2.7 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2986) PRAI PF00697.22 KPA46471.1 - 0.034 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Mitoc_mL59 PF18126.1 KPA46472.1 - 3.9e-45 153.3 3.0 4.5e-45 153.1 3.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 zf-CSL PF05207.13 KPA46473.1 - 1.9e-21 75.5 2.8 2.8e-21 75.0 2.8 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KPA46473.1 - 2.1e-11 43.8 0.0 3.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain 14-3-3 PF00244.20 KPA46474.1 - 1.9e-106 354.6 3.7 2.2e-106 354.3 3.7 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 KPA46474.1 - 0.26 11.8 3.4 0.76 10.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat IATP PF04568.12 KPA46475.1 - 1.1e-30 105.9 0.5 1.3e-30 105.7 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF489 PF04356.12 KPA46475.1 - 0.067 13.2 0.8 0.086 12.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) IKKbetaNEMObind PF12179.8 KPA46475.1 - 0.15 12.1 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DUF2205 PF10224.9 KPA46475.1 - 0.17 11.9 5.3 0.23 11.5 5.3 1.2 1 0 0 1 1 1 0 Short coiled-coil protein NPV_P10 PF05531.12 KPA46475.1 - 0.17 12.3 0.8 0.24 11.9 0.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Nsp1_C PF05064.13 KPA46476.1 - 2e-39 134.0 3.1 2e-39 134.0 3.1 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KPA46476.1 - 4.1e-17 62.8 191.7 9.4e-06 26.4 31.9 8.0 1 1 5 6 6 5 5 Nucleoporin FG repeat region ERM PF00769.19 KPA46476.1 - 0.071 12.9 8.5 0.11 12.3 8.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family NPV_P10 PF05531.12 KPA46476.1 - 0.18 12.3 1.9 0.6 10.6 0.2 2.5 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BRE1 PF08647.11 KPA46476.1 - 0.39 10.8 5.8 0.82 9.8 1.7 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase V-SNARE PF05008.15 KPA46476.1 - 0.42 11.0 8.0 0.39 11.1 0.5 3.1 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus MAS20 PF02064.15 KPA46476.1 - 0.74 9.9 2.3 1.5 8.9 2.3 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor MIP-T3_C PF17749.1 KPA46476.1 - 1.2 9.1 7.1 1.1 9.3 0.0 3.0 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF1664 PF07889.12 KPA46476.1 - 2.5 8.2 3.7 36 4.4 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Rotamase PF00639.21 KPA46476.1 - 3 8.9 5.0 37 5.4 0.2 3.3 2 1 0 2 2 2 0 PPIC-type PPIASE domain CENP-Q PF13094.6 KPA46476.1 - 3.1 8.0 7.4 6.3 7.0 7.4 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_13 PF13166.6 KPA46476.1 - 3.4 6.2 8.0 6.9 5.2 2.3 2.0 1 1 1 2 2 2 0 AAA domain DUF724 PF05266.14 KPA46476.1 - 4.8 7.0 7.9 3.2 7.5 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4200 PF13863.6 KPA46476.1 - 5.6 7.4 10.9 15 6.0 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) KxDL PF10241.9 KPA46476.1 - 6.3 7.2 7.4 15 6.0 0.1 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein APG6_N PF17675.1 KPA46476.1 - 7.9 7.0 13.9 12 6.4 6.7 2.2 1 1 0 2 2 2 0 Apg6 coiled-coil region DUF5102 PF17104.5 KPA46477.1 - 6.1e-113 377.7 3.1 6.1e-113 377.7 3.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF5102) Nop14 PF04147.12 KPA46477.1 - 3.6 5.7 20.7 5.5 5.1 20.7 1.2 1 0 0 1 1 1 0 Nop14-like family eIF2_C PF09173.11 KPA46478.1 - 2.6e-34 117.3 0.5 6e-34 116.2 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KPA46478.1 - 2e-22 79.7 1.7 2.7e-21 76.0 1.7 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KPA46478.1 - 4.1e-09 36.7 0.2 8.4e-09 35.7 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KPA46478.1 - 0.0036 17.4 0.0 0.0075 16.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KPA46478.1 - 0.0059 16.6 0.8 0.018 15.1 0.1 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 KPA46478.1 - 0.024 14.6 0.2 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase MARVEL PF01284.23 KPA46479.1 - 0.0011 18.9 6.2 0.0011 18.9 6.2 2.2 1 1 1 2 2 2 1 Membrane-associating domain Ninjurin PF04923.12 KPA46479.1 - 0.0067 16.4 3.0 0.0078 16.1 0.4 2.0 2 0 0 2 2 2 1 Ninjurin 7tm_3 PF00003.22 KPA46479.1 - 0.0075 16.0 9.3 0.14 11.8 4.4 2.1 2 0 0 2 2 2 2 7 transmembrane sweet-taste receptor of 3 GCPR DUF2569 PF10754.9 KPA46479.1 - 0.019 15.4 2.0 0.019 15.4 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF4064 PF13273.6 KPA46479.1 - 0.032 14.5 7.0 1.3 9.3 0.2 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF4064) DUF996 PF06195.13 KPA46479.1 - 0.14 12.5 4.0 1.6 9.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) SfLAP PF11139.8 KPA46479.1 - 0.14 11.6 2.4 0.78 9.1 2.8 1.9 1 1 1 2 2 2 0 Sap, sulfolipid-1-addressing protein Peptidase_M56 PF05569.11 KPA46479.1 - 0.2 10.8 3.9 0.32 10.2 3.9 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF3290 PF11694.8 KPA46479.1 - 0.23 11.4 3.5 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) SCIMP PF15050.6 KPA46479.1 - 0.39 11.2 3.0 0.46 11.0 0.0 2.6 4 0 0 4 4 3 0 SCIMP protein Vut_1 PF02592.15 KPA46479.1 - 0.87 9.9 5.8 1.6 9.1 5.8 1.3 1 0 0 1 1 1 0 Putative vitamin uptake transporter Frag1 PF10277.9 KPA46479.1 - 0.98 8.9 9.6 0.99 8.9 5.3 2.0 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family DHHC PF01529.20 KPA46479.1 - 2.1 8.5 10.1 0.94 9.6 3.1 2.1 1 1 0 2 2 2 0 DHHC palmitoyltransferase TMEM190 PF15431.6 KPA46479.1 - 5.3 7.2 7.3 39 4.4 0.1 3.4 1 1 1 4 4 4 0 Transmembrane protein 190 DEAD PF00270.29 KPA46480.1 - 1.1e-45 155.5 1.4 1.8e-45 154.9 1.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA46480.1 - 6.3e-32 110.2 0.4 8.7e-31 106.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA46480.1 - 2.9e-06 27.4 0.0 4.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KPA46480.1 - 0.0001 22.7 0.3 0.00088 19.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPA46480.1 - 0.00023 21.0 0.2 0.00046 20.0 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KPA46480.1 - 0.016 15.5 0.7 0.08 13.2 0.7 2.1 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 KPA46480.1 - 0.026 13.9 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 KPA46480.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Helicase UvrD-helicase PF00580.21 KPA46480.1 - 0.076 12.5 0.4 0.11 12.0 0.4 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 KPA46480.1 - 0.082 12.9 0.0 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain IL17R_D_N PF16742.5 KPA46480.1 - 0.083 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Cupin_8 PF13621.6 KPA46481.1 - 9.6e-20 71.4 0.1 5.7e-18 65.5 0.1 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KPA46481.1 - 2.6e-10 40.7 0.0 9.6e-10 38.9 0.0 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 KPA46481.1 - 1.1e-07 31.7 0.1 2.5e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA46481.1 - 5.5e-05 22.9 0.1 0.00017 21.4 0.1 1.8 1 0 0 1 1 1 1 F-box domain Cupin_4 PF08007.12 KPA46481.1 - 0.00099 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein DUF1771 PF08590.10 KPA46482.1 - 1.6e-14 54.0 11.9 3.3e-14 53.0 11.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KPA46482.1 - 3.3e-08 33.3 7.9 1e-05 25.4 0.4 2.9 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 KPA46482.1 - 1.2e-06 28.8 0.0 3.4e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 KPA46482.1 - 2.6e-06 27.2 3.3 0.001 18.9 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KPA46482.1 - 0.00025 21.4 4.5 0.11 13.0 0.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KPA46482.1 - 0.00037 20.2 11.1 0.0056 16.5 0.3 3.1 2 1 0 2 2 2 1 CCCH-type zinc finger HBS1_N PF08938.10 KPA46482.1 - 0.056 13.7 0.0 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 HBS1 N-terminus Torus PF16131.5 KPA46482.1 - 0.28 11.9 4.7 1.5 9.6 0.4 2.3 1 1 1 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 KPA46482.1 - 0.53 10.5 3.2 16 5.7 0.2 2.2 1 1 1 2 2 2 0 Zinc-finger containing family SNARE_assoc PF09335.11 KPA46483.1 - 1.2e-16 61.3 5.4 1.2e-16 61.3 5.4 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein PMP1_2 PF08114.11 KPA46483.1 - 0.15 11.8 3.2 2.2 8.1 0.1 3.3 3 0 0 3 3 3 0 ATPase proteolipid family Abhydrolase_1 PF00561.20 KPA46485.1 - 2e-13 50.6 0.0 4.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA46485.1 - 1.7e-07 30.8 0.0 3.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPA46485.1 - 0.0021 17.6 0.1 0.0063 16.0 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 KPA46485.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Peptidase_S15 PF02129.18 KPA46485.1 - 0.061 12.9 0.0 0.36 10.4 0.0 2.1 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KPA46485.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative esterase BTB PF00651.31 KPA46486.1 - 0.00019 21.6 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-ribbon_3 PF13248.6 KPA46486.1 - 0.13 11.7 0.2 0.13 11.7 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain SR-25 PF10500.9 KPA46486.1 - 0.26 10.9 8.2 0.4 10.3 8.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 KPA46486.1 - 0.72 9.5 3.2 1.1 8.9 3.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DEAD PF00270.29 KPA46487.1 - 2.4e-08 33.9 0.1 1.3e-07 31.6 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.6 KPA46487.1 - 0.015 15.9 0.0 0.058 14.0 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain Cdd1 PF11731.8 KPA46487.1 - 0.078 13.2 0.0 0.94 9.8 0.0 2.5 3 0 0 3 3 3 0 Pathogenicity locus zf-HC5HC2H_2 PF13832.6 KPA46488.1 - 1.5e-21 76.6 2.5 1.5e-21 76.6 2.5 4.5 5 0 0 5 5 5 2 PHD-zinc-finger like domain BAH PF01426.18 KPA46488.1 - 1.6e-17 63.5 0.0 3.5e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KPA46488.1 - 5.3e-17 61.9 3.9 5.3e-17 61.9 3.9 4.9 4 1 1 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.29 KPA46488.1 - 3.3e-13 49.3 53.5 9e-07 28.7 8.5 6.3 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.6 KPA46488.1 - 2.8e-08 33.1 3.7 2.8e-08 33.1 3.7 5.5 7 0 0 7 7 7 2 PHD-finger C1_1 PF00130.22 KPA46488.1 - 0.001 18.9 1.4 0.001 18.9 1.4 6.0 6 1 1 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KPA46488.1 - 0.0064 16.4 34.1 0.045 13.7 6.3 4.5 4 0 0 4 4 4 2 Prokaryotic RING finger family 1 C1_2 PF03107.16 KPA46488.1 - 0.02 15.2 0.3 0.02 15.2 0.3 6.6 8 0 0 8 8 8 0 C1 domain ELM2 PF01448.24 KPA46488.1 - 0.026 15.3 3.0 0.06 14.1 0.3 2.9 2 0 0 2 2 2 0 ELM2 domain TrkA_C PF02080.21 KPA46488.1 - 0.15 11.9 0.0 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-C domain FAM220 PF15487.6 KPA46488.1 - 0.5 10.0 16.3 3.2 7.3 2.2 2.7 2 0 0 2 2 2 0 FAM220 family Pkinase PF00069.25 KPA46489.1 - 6.5e-35 120.8 0.0 3.5e-20 72.5 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46489.1 - 8.9e-14 51.4 0.1 8.5e-13 48.2 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPA46489.1 - 0.0064 16.4 0.2 0.016 15.1 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KPA46489.1 - 0.024 14.0 0.0 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Glyco_hydro_38N PF01074.22 KPA46490.1 - 9.4e-88 294.3 0.7 1.4e-87 293.7 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KPA46490.1 - 3.9e-53 180.7 0.2 9.8e-53 179.4 0.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KPA46490.1 - 2e-28 98.4 0.0 6.6e-28 96.7 0.0 2.0 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KPA46490.1 - 1.3e-13 50.8 0.2 4.1e-13 49.2 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Na_trans_assoc PF06512.13 KPA46491.1 - 0.0046 17.3 8.2 0.0077 16.5 8.2 1.3 1 0 0 1 1 1 1 Sodium ion transport-associated Thioredoxin_12 PF18400.1 KPA46491.1 - 0.1 12.4 0.6 0.18 11.7 0.6 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain MutS_V PF00488.21 KPA46492.1 - 1.2e-69 234.1 0.1 2.9e-69 232.9 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KPA46492.1 - 2.9e-45 154.9 6.7 4.8e-45 154.1 6.7 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KPA46492.1 - 5.3e-18 65.3 0.0 1.5e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KPA46492.1 - 1.4e-08 35.1 0.0 5.2e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 MutS domain II DUF494 PF04361.13 KPA46492.1 - 0.03 14.2 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF494) CobA_CobO_BtuR PF02572.15 KPA46492.1 - 0.062 13.6 0.1 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Ribosomal_L10 PF00466.20 KPA46493.1 - 5.8e-25 87.3 0.1 1.5e-24 86.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KPA46493.1 - 7.8e-22 77.1 0.0 1.5e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KPA46493.1 - 5.5e-17 62.1 7.3 6.1e-17 62.0 4.3 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein DXP_reductoisom PF02670.16 KPA46493.1 - 0.0098 16.6 0.0 1 10.1 0.0 2.3 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase VirE_N PF08800.10 KPA46493.1 - 0.039 14.1 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 VirE N-terminal domain WD40 PF00400.32 KPA46494.1 - 5.4e-05 23.9 0.2 1.6 9.7 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat CDC45 PF02724.14 KPA46494.1 - 0.37 9.0 3.2 0.59 8.4 3.2 1.4 1 0 0 1 1 1 0 CDC45-like protein DnaJ_C PF01556.18 KPA46495.1 - 2.9e-37 128.0 0.1 3.8e-37 127.7 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KPA46495.1 - 3.4e-26 91.1 2.9 6.4e-26 90.3 2.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KPA46495.1 - 1.9e-16 60.2 17.9 3.3e-16 59.4 17.9 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF2614 PF11023.8 KPA46495.1 - 0.37 10.9 7.0 1.1 9.3 1.5 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain zinc_ribbon_9 PF14369.6 KPA46495.1 - 0.44 10.9 2.2 32 4.9 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon Anti-TRAP PF15777.5 KPA46495.1 - 0.64 10.0 17.8 0.54 10.2 3.8 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KPA46495.1 - 0.68 10.0 10.1 0.44 10.6 2.7 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 KPA46495.1 - 1.5 8.8 8.7 4.8 7.2 2.4 2.4 1 1 0 2 2 2 0 zinc-ribbons DUF3425 PF11905.8 KPA46496.1 - 2e-15 56.9 0.0 4.1e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 KPA46496.1 - 0.0011 19.0 7.4 0.0019 18.2 7.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper MAT1 PF06391.13 KPA46496.1 - 0.042 13.7 0.7 0.042 13.7 0.7 1.5 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 CAP_GLY PF01302.25 KPA46497.1 - 1.6e-18 66.5 0.5 5.9e-18 64.6 0.7 1.9 2 0 0 2 2 2 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KPA46497.1 - 7e-08 32.2 11.4 0.00043 20.1 1.3 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle Spc7 PF08317.11 KPA46497.1 - 3.2e-05 23.0 27.6 0.046 12.6 4.9 3.2 2 1 1 3 3 3 3 Spc7 kinetochore protein Med4 PF10018.9 KPA46497.1 - 0.0083 15.8 2.2 0.0083 15.8 2.2 2.9 2 1 0 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF3584 PF12128.8 KPA46497.1 - 0.087 10.3 22.2 0.13 9.7 22.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 KPA46497.1 - 0.14 12.6 12.0 2.9 8.4 0.3 3.8 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Csm1_N PF18504.1 KPA46497.1 - 0.22 11.9 20.1 4.5 7.7 0.0 5.4 4 1 1 5 5 5 0 Csm1 N-terminal domain XLF PF09302.11 KPA46497.1 - 0.94 9.6 11.4 4.1 7.5 0.1 4.1 2 1 1 4 4 4 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component FAM76 PF16046.5 KPA46497.1 - 0.96 8.7 16.7 5.9 6.2 1.9 3.3 2 1 1 3 3 3 0 FAM76 protein DUF1664 PF07889.12 KPA46497.1 - 1 9.4 14.8 2.1 8.4 1.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KPA46497.1 - 1.1 8.6 18.8 0.29 10.4 5.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Glutaredoxin2_C PF04399.13 KPA46497.1 - 1.8 8.4 4.0 9.1 6.1 0.5 2.5 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain zf_PR_Knuckle PF18445.1 KPA46497.1 - 2.2 8.2 4.4 8.6 6.3 0.2 2.5 2 0 0 2 2 2 0 PR zinc knuckle motif Exonuc_VII_S PF02609.16 KPA46497.1 - 2.3 8.3 14.0 0.045 13.8 5.4 2.6 2 0 0 2 2 2 0 Exonuclease VII small subunit Filament PF00038.21 KPA46497.1 - 2.9 7.4 29.5 4 6.9 9.7 3.2 2 1 1 3 3 3 0 Intermediate filament protein TMF_DNA_bd PF12329.8 KPA46497.1 - 3.2 7.8 36.7 0.063 13.3 2.5 5.4 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.6 KPA46497.1 - 4 6.0 18.7 0.16 10.6 6.2 2.7 2 1 0 3 3 3 0 AAA domain CENP-F_leu_zip PF10473.9 KPA46497.1 - 4.2 7.4 33.0 1.5 8.8 5.2 3.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.20 KPA46497.1 - 5.4 7.0 21.6 2.4 8.2 0.5 4.2 3 1 2 5 5 5 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 KPA46497.1 - 7.5 6.6 34.1 2.2 8.3 12.5 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 KPA46497.1 - 9.2 6.6 28.5 27 5.1 0.6 4.2 2 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Glycogen_syn PF05693.13 KPA46498.1 - 0 1179.9 0.0 0 1179.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 KPA46498.1 - 1.6e-05 25.0 0.2 4e-05 23.7 0.2 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KPA46498.1 - 3.4e-05 23.6 0.1 7.4e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KPA46498.1 - 5.9e-05 22.7 0.0 0.0042 16.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KPA46498.1 - 6.5e-05 23.4 0.0 0.061 13.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KPA46498.1 - 0.00051 20.5 0.2 0.0015 19.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain WD40 PF00400.32 KPA46499.1 - 5.9e-19 68.1 15.8 8.7e-06 26.4 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 KPA46499.1 - 3.2e-15 56.4 0.3 5.5e-15 55.7 0.3 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain T3SS_HrpK1 PF16937.5 KPA46499.1 - 0.063 12.9 0.3 0.24 11.1 0.0 1.9 1 1 0 2 2 2 0 Type III secretion system translocator protein, HrpF Nup160 PF11715.8 KPA46499.1 - 0.23 10.1 1.2 1 7.9 0.9 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 DNA_pol_A_exo1 PF01612.20 KPA46500.1 - 2.8e-16 59.8 0.0 4.8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HTH_40 PF14493.6 KPA46500.1 - 0.13 12.8 0.0 0.36 11.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain LSM PF01423.22 KPA46501.1 - 4.8e-23 80.6 0.1 5.3e-23 80.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KPA46501.1 - 0.023 14.8 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 KPA46501.1 - 0.13 12.4 0.0 0.16 12.1 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain RNA_pol_L_2 PF13656.6 KPA46502.1 - 9.5e-23 79.8 0.2 1.4e-22 79.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KPA46502.1 - 8.6e-07 28.3 0.0 2.3e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MTS PF05175.14 KPA46503.1 - 5.6e-07 29.3 0.0 3.6e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_10 PF05971.12 KPA46503.1 - 9.7e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase PrmA PF06325.13 KPA46503.1 - 0.00016 21.1 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.16 KPA46503.1 - 0.00082 18.7 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_31 PF13847.6 KPA46503.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA46503.1 - 0.0085 16.8 0.0 0.018 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 KPA46503.1 - 0.012 15.0 0.1 0.33 10.4 0.0 2.0 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 KPA46503.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 KPA46503.1 - 0.073 12.7 0.1 0.8 9.4 0.1 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmC_N PF17827.1 KPA46503.1 - 0.08 13.5 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 PrmC N-terminal domain Met_10 PF02475.16 KPA46503.1 - 0.18 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Peptidase_M41 PF01434.18 KPA46504.1 - 1e-68 230.9 0.0 1.6e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KPA46504.1 - 1.7e-42 145.0 0.1 1.4e-41 142.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA46504.1 - 1.8e-13 50.0 0.0 5.2e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KPA46504.1 - 2.9e-12 46.9 0.0 9.5e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.13 KPA46504.1 - 0.0013 18.0 0.1 0.0075 15.5 0.1 2.2 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_5 PF07728.14 KPA46504.1 - 0.0017 18.3 0.0 0.0074 16.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KPA46504.1 - 0.012 15.3 0.0 0.058 13.1 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KPA46504.1 - 0.019 15.3 0.3 1.5 9.1 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 KPA46504.1 - 0.023 14.8 0.0 0.08 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KPA46504.1 - 0.025 15.0 0.6 0.56 10.6 0.1 2.8 2 1 0 3 3 2 0 AAA ATPase domain AAA_33 PF13671.6 KPA46504.1 - 0.052 13.7 0.1 0.58 10.3 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.6 KPA46504.1 - 0.085 13.3 0.0 0.28 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KPA46504.1 - 0.14 11.8 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KPA46504.1 - 0.16 12.5 0.5 2.8 8.5 0.1 2.7 3 0 0 3 3 2 0 AAA domain HCO3_cotransp PF00955.21 KPA46505.1 - 7.8e-85 285.6 8.5 7.2e-46 157.1 5.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family TNFR_16_TM PF18422.1 KPA46505.1 - 0.43 10.6 6.4 0.15 12.1 1.1 2.7 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain TIMELESS PF04821.14 KPA46506.1 - 1.1e-85 287.2 0.0 1.1e-85 287.2 0.0 3.1 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 KPA46506.1 - 3.2e-26 92.6 48.8 3.2e-26 92.6 48.8 3.9 3 2 0 3 3 3 1 Timeless protein C terminal region 3HCDH_N PF02737.18 KPA46507.1 - 2.8e-52 177.2 1.3 3.7e-52 176.8 1.3 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KPA46507.1 - 1.1e-31 109.3 0.0 2.4e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KPA46507.1 - 0.00017 21.8 0.9 0.00056 20.2 0.5 2.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 KPA46507.1 - 0.0013 18.1 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KPA46507.1 - 0.0036 17.5 0.4 0.0099 16.1 0.3 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 KPA46507.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 KPA46507.1 - 0.034 13.8 0.1 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KPA46507.1 - 0.039 13.3 0.3 0.1 12.0 0.3 1.8 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KPA46507.1 - 0.042 14.1 0.2 0.15 12.3 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KPA46507.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KPA46507.1 - 0.1 13.1 0.1 0.24 12.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 KPA46507.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KPA46507.1 - 0.12 12.9 4.6 1.4 9.5 4.3 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Homeodomain PF00046.29 KPA46508.1 - 5.6e-18 64.5 3.4 1.1e-17 63.6 3.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KPA46508.1 - 0.0023 17.8 0.1 0.0068 16.3 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain vMSA PF00695.19 KPA46508.1 - 0.24 10.5 6.8 0.32 10.1 6.8 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Rox3 PF08633.10 KPA46509.1 - 8e-65 219.0 0.4 8e-65 219.0 0.4 1.8 2 0 0 2 2 2 1 Rox3 mediator complex subunit Fungal_trans PF04082.18 KPA46510.1 - 1.4e-25 89.8 0.1 5.7e-25 87.8 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Folliculin PF11704.8 KPA46510.1 - 0.0093 15.9 0.7 0.055 13.4 1.5 1.8 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport PEHE PF15275.6 KPA46510.1 - 0.22 12.2 2.6 0.44 11.2 2.6 1.4 1 0 0 1 1 1 0 PEHE domain efThoc1 PF11957.8 KPA46510.1 - 1.3 7.6 3.3 1 8.0 0.0 2.0 2 0 0 2 2 2 0 THO complex subunit 1 transcription elongation factor Zn_clus PF00172.18 KPA46511.1 - 1.2e-10 41.3 11.5 1.9e-10 40.7 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KPA46511.1 - 0.0065 16.6 0.1 0.017 15.3 0.1 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain Adeno_E3_CR2 PF02439.15 KPA46512.1 - 0.032 14.0 0.2 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KPA46512.1 - 0.19 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain F-box-like PF12937.7 KPA46513.1 - 9e-05 22.3 1.3 0.00018 21.3 1.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA46513.1 - 0.00016 21.5 0.6 0.00066 19.5 0.6 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KPA46513.1 - 0.072 13.0 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 F-box PGAP1 PF07819.13 KPA46514.1 - 8.3e-06 25.7 0.1 6e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 KPA46514.1 - 1.1e-05 25.0 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KPA46514.1 - 0.00095 19.8 3.0 0.00095 19.8 3.0 2.2 2 1 1 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA46514.1 - 0.0024 17.2 0.0 0.0053 16.1 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF3665 PF12427.8 KPA46514.1 - 0.043 13.5 3.2 0.13 12.0 3.2 1.8 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Abhydrolase_1 PF00561.20 KPA46514.1 - 0.096 12.3 0.5 0.53 9.9 0.0 2.4 2 2 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KPA46514.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 KPA46514.1 - 1 9.4 0.0 1 9.4 0.0 2.5 2 1 1 3 3 3 0 Thioesterase domain HET PF06985.11 KPA46515.1 - 1.7e-20 73.9 0.0 3.2e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 KPA46516.1 - 4.4e-15 55.2 0.0 1.7e-07 30.2 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme DEAD PF00270.29 KPA46517.1 - 6.4e-48 162.8 0.0 2.3e-47 161.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA46517.1 - 9.2e-33 112.9 0.0 3.1e-32 111.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA46517.1 - 0.0027 17.8 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KPA46517.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KPA46517.1 - 0.22 10.7 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Proteasome PF00227.26 KPA46518.1 - 7.8e-32 110.3 0.0 8.7e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sigma54_AID PF00309.20 KPA46518.1 - 0.029 14.2 0.0 0.062 13.2 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) WD40 PF00400.32 KPA46519.1 - 1.1e-20 73.5 8.5 0.00013 22.7 0.3 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 KPA46519.1 - 0.00059 19.3 0.0 0.015 14.7 0.0 2.9 3 1 0 4 4 4 1 WD40-like domain ANAPC4_WD40 PF12894.7 KPA46519.1 - 0.0012 19.0 0.1 0.033 14.5 0.0 3.1 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA46519.1 - 0.0044 15.7 0.0 3.9 6.0 0.1 3.2 2 2 2 4 4 4 2 Nucleoporin Nup120/160 Nha1_C PF08619.10 KPA46519.1 - 0.091 12.0 10.7 0.17 11.1 10.7 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Peptidase_C48 PF02902.19 KPA46520.1 - 8e-34 117.4 0.0 2.2e-33 115.9 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SPC22 PF04573.12 KPA46522.1 - 9e-42 142.5 0.4 1.9e-31 108.8 0.1 2.0 2 0 0 2 2 2 2 Signal peptidase subunit XRN_M PF17846.1 KPA46523.1 - 2.2e-102 343.3 4.4 4.5e-102 342.3 4.4 1.5 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KPA46523.1 - 6.8e-97 323.6 0.0 1.1e-96 323.0 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KPA46523.1 - 1.9e-71 239.8 0.0 3.9e-71 238.8 0.0 1.6 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KPA46523.1 - 5.6e-37 125.8 0.0 1.7e-36 124.3 0.0 1.9 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KPA46523.1 - 1.3e-20 73.2 0.1 2.6e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KPA46523.1 - 5.9e-07 29.5 0.6 1.3e-06 28.4 0.6 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 Sterile PF03015.19 KPA46523.1 - 0.027 14.7 0.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein DsrD PF08679.11 KPA46523.1 - 0.88 9.9 2.5 1 9.7 0.1 2.4 3 0 0 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) WD40 PF00400.32 KPA46524.1 - 2.5e-29 100.9 1.8 6.8e-06 26.7 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KPA46524.1 - 3.7e-27 94.4 0.2 2.7e-26 91.6 0.2 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KPA46524.1 - 1e-07 32.1 0.9 0.014 15.7 0.2 4.7 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPA46524.1 - 0.06 12.0 0.3 0.28 9.8 0.5 1.9 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Sporozoite_P67 PF05642.11 KPA46525.1 - 2.9 5.8 6.0 5 5.1 6.0 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-RanBP PF00641.18 KPA46526.1 - 2.6e-18 65.0 13.3 8.8e-11 40.9 1.6 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KPA46526.1 - 2.9e-08 33.4 0.0 6.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KPA46526.1 - 3.9e-07 30.8 0.0 5.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Pmp3 PF01679.17 KPA46527.1 - 2.5e-21 75.6 9.3 3.1e-21 75.3 9.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pkinase PF00069.25 KPA46529.1 - 9.9e-69 231.6 0.0 1.4e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46529.1 - 6e-37 127.3 0.1 1.7e-36 125.8 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA46529.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KPA46529.1 - 0.0049 16.2 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KPA46529.1 - 0.021 14.4 0.1 0.058 13.0 0.1 1.7 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KPA46529.1 - 0.068 12.1 0.2 0.17 10.8 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KPA46529.1 - 0.37 9.5 0.0 0.37 9.5 0.0 2.9 3 1 0 3 3 3 0 Fungal protein kinase Abhydrolase_1 PF00561.20 KPA46530.1 - 8.4e-11 42.0 0.1 2.9e-09 36.9 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA46530.1 - 1.2e-09 37.8 0.0 4.2e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 NADH_B2 PF14813.6 KPA46531.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 DUF2052 PF09747.9 KPA46531.1 - 2.2 8.4 13.4 0.31 11.2 7.4 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) GATA PF00320.27 KPA46533.1 - 4.7e-16 58.1 3.5 7.4e-16 57.5 3.5 1.3 1 0 0 1 1 1 1 GATA zinc finger GCS PF03074.16 KPA46534.1 - 5.3e-174 578.8 0.0 6.3e-174 578.5 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Endosulfine PF04667.17 KPA46535.1 - 1.4e-26 92.4 0.0 2e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region BESS PF02944.20 KPA46535.1 - 0.2 11.5 0.2 2 8.3 0.0 2.2 2 0 0 2 2 2 0 BESS motif UPF0160 PF03690.13 KPA46536.1 - 3e-133 444.4 0.0 3.4e-133 444.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) G-alpha PF00503.20 KPA46537.1 - 1.5e-108 363.2 0.0 1.8e-108 362.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KPA46537.1 - 1.4e-13 50.7 0.5 3e-08 33.3 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KPA46537.1 - 0.00041 19.8 0.5 0.054 12.8 0.0 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KPA46537.1 - 0.081 13.1 0.1 6.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DAP3 PF10236.9 KPA46537.1 - 0.095 11.9 0.3 0.16 11.1 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 FtsK_SpoIIIE PF01580.18 KPA46537.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KPA46537.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Vps62 PF06101.11 KPA46538.1 - 5e-10 38.3 0.3 5e-10 38.3 0.3 1.5 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 TFIIIC_sub6 PF10419.9 KPA46539.1 - 2.8e-26 91.2 0.0 4.9e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain His_biosynth PF00977.21 KPA46540.1 - 2.1e-49 168.1 0.2 8.3e-49 166.1 0.2 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KPA46540.1 - 4.3e-22 78.8 0.0 6.7e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KPA46540.1 - 3.8e-09 36.6 0.0 5.1e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KPA46540.1 - 4.6e-07 29.6 0.0 1.3e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.17 KPA46540.1 - 0.12 11.4 0.1 0.43 9.6 0.0 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.13 KPA46540.1 - 0.13 12.0 0.1 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 NMO PF03060.15 KPA46540.1 - 0.16 11.3 0.3 0.44 9.9 0.0 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase ODC_AZ PF02100.17 KPA46541.1 - 9.4e-45 151.3 0.1 1.4e-44 150.8 0.1 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ArfGap PF01412.18 KPA46542.1 - 2.7e-38 130.6 0.5 6.3e-38 129.4 0.5 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.31 KPA46542.1 - 0.007 16.3 1.2 0.014 15.3 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Oxysterol_BP PF01237.18 KPA46543.1 - 4e-111 371.5 0.0 1.3e-110 369.7 0.0 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KPA46543.1 - 8e-38 128.6 0.2 6.2e-37 125.8 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KPA46543.1 - 9.4e-09 35.7 0.1 3.7e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_17 PF18012.1 KPA46543.1 - 0.031 14.0 0.2 0.32 10.7 0.2 2.3 2 0 0 2 2 2 0 PH domain Glyco_hydro_72 PF03198.14 KPA46544.1 - 1.6e-126 421.9 2.9 2e-126 421.5 2.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KPA46544.1 - 1.4e-05 24.7 0.4 0.00042 19.8 0.4 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CENP-K PF11802.8 KPA46545.1 - 6.4e-10 39.0 2.7 0.0013 18.4 5.2 2.3 2 0 0 2 2 2 2 Centromere-associated protein K Serine_rich PF08824.10 KPA46545.1 - 0.86 9.6 8.1 0.89 9.5 0.2 2.9 3 1 0 3 3 3 0 Serine rich protein interaction domain DUF1664 PF07889.12 KPA46545.1 - 0.99 9.5 7.8 0.26 11.3 0.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) HOOK PF05622.12 KPA46545.1 - 1.9 6.5 15.8 0.19 9.8 8.2 2.1 2 0 0 2 2 2 0 HOOK protein UPF0242 PF06785.11 KPA46545.1 - 2.1 8.4 14.9 0.062 13.4 6.4 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BAF1_ABF1 PF04684.13 KPA46545.1 - 5.7 5.9 10.6 0.2 10.7 2.5 2.1 1 1 1 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DinB_2 PF12867.7 KPA46545.1 - 6 7.4 11.9 1.1e+04 -3.1 11.9 3.4 1 1 0 1 1 1 0 DinB superfamily SlyX PF04102.12 KPA46545.1 - 7.4 7.3 17.9 1.6 9.4 1.8 4.1 3 1 0 3 3 3 0 SlyX Laminin_II PF06009.12 KPA46545.1 - 8.6 6.4 13.0 4.6 7.3 1.2 3.3 4 0 0 4 4 4 0 Laminin Domain II Phos_pyr_kin PF08543.12 KPA46546.1 - 6.9e-10 38.7 0.0 9.8e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KPA46546.1 - 6e-07 29.1 0.1 7.6e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 pfkB family carbohydrate kinase PCNA_N PF00705.18 KPA46547.1 - 4.9e-55 184.6 5.1 7.9e-55 184.0 4.3 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KPA46547.1 - 3.4e-52 176.0 0.1 3.9e-50 169.3 0.0 2.1 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KPA46547.1 - 3.9e-09 36.3 0.2 4.7e-09 36.1 0.2 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KPA46547.1 - 2.3e-05 23.6 0.9 0.0014 17.8 0.9 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KPA46547.1 - 5.4e-05 22.5 0.4 0.00075 18.7 0.1 2.1 2 0 0 2 2 2 1 Hus1-like protein Vezatin PF12632.7 KPA46548.1 - 1.2e-74 251.2 0.2 1.7e-74 250.7 0.2 1.2 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF4131 PF13567.6 KPA46548.1 - 0.12 12.0 1.1 0.31 10.7 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4231 PF14015.6 KPA46548.1 - 0.22 12.0 1.9 0.38 11.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) zf-RING_2 PF13639.6 KPA46551.1 - 2.3e-10 40.6 6.4 3.7e-10 40.0 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KPA46551.1 - 1.8e-09 37.8 4.7 3.2e-09 36.9 4.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KPA46551.1 - 2e-07 31.0 1.0 3.7e-07 30.1 1.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KPA46551.1 - 1.1e-05 25.3 2.3 1.7e-05 24.7 1.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KPA46551.1 - 1.4e-05 24.9 6.5 3.3e-05 23.6 6.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPA46551.1 - 6.6e-05 22.8 4.7 0.0001 22.2 4.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KPA46551.1 - 0.00034 20.4 5.4 0.00054 19.8 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPA46551.1 - 0.00053 19.8 5.2 0.001 18.9 5.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KPA46551.1 - 0.00093 19.0 5.3 0.0018 18.1 5.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPA46551.1 - 0.038 14.2 0.6 0.038 14.2 0.6 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KPA46551.1 - 0.048 13.8 5.9 0.95 9.7 5.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 KPA46551.1 - 0.091 12.5 2.6 0.29 10.9 2.6 1.9 1 1 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KPA46551.1 - 0.11 12.1 6.2 0.25 11.0 6.2 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rtf2 PF04641.12 KPA46551.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Cullin PF00888.22 KPA46552.1 - 6.8e-24 84.4 0.0 1.2e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KPA46552.1 - 3.2e-21 75.6 0.2 8e-21 74.3 0.2 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 CAP_N PF01213.19 KPA46552.1 - 4.6 6.6 4.7 9.5 5.6 4.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-C2H2 PF00096.26 KPA46553.1 - 0.0061 17.0 4.1 0.44 11.1 0.6 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 KPA46553.1 - 0.1 12.0 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain MFS_2 PF13347.6 KPA46554.1 - 9e-13 47.6 9.6 9e-13 47.6 9.6 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 KPA46554.1 - 0.001 18.0 5.0 0.001 18.0 5.0 2.1 3 0 0 3 3 3 1 MFS_1 like family RhoGEF PF00621.20 KPA46555.1 - 4.9e-29 101.9 0.0 9.7e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 KPA46555.1 - 1.3e-07 31.5 2.2 1.3e-07 31.5 2.2 2.1 2 1 0 2 2 2 1 BAR domain Telomerase_RBD PF12009.8 KPA46556.1 - 2.4e-52 176.6 0.5 5e-52 175.5 0.5 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KPA46556.1 - 7.6e-13 48.5 0.0 7.3e-09 35.5 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MBOAT_2 PF13813.6 KPA46557.1 - 7.8e-16 58.1 3.1 1e-15 57.8 1.6 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Zn_clus PF00172.18 KPA46558.1 - 1.1e-06 28.6 10.1 2.9e-06 27.3 10.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol3_chi PF04364.13 KPA46558.1 - 0.016 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC Mito_carr PF00153.27 KPA46560.1 - 1.3e-67 223.8 0.4 4.2e-21 74.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPA46560.1 - 0.65 9.1 2.6 1.1 8.3 0.1 2.4 3 0 0 3 3 3 0 Gammaproteobacterial serine protease IU_nuc_hydro PF01156.19 KPA46561.1 - 1.4e-81 274.4 0.0 1.7e-81 274.2 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.13 KPA46562.1 - 3.3e-09 36.7 10.1 3.3e-09 36.7 10.1 2.9 3 0 0 3 3 3 1 RED-like protein N-terminal region Lsm_interact PF05391.11 KPA46562.1 - 0.054 13.0 0.3 0.15 11.6 0.3 1.8 1 0 0 1 1 1 0 Lsm interaction motif DUF2924 PF11149.8 KPA46562.1 - 0.35 11.2 3.7 0.57 10.6 0.3 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2924) GvpG PF05120.12 KPA46562.1 - 2.8 8.0 8.8 0.59 10.2 3.9 2.4 2 0 0 2 2 2 0 Gas vesicle protein G IMS PF00817.20 KPA46563.1 - 5.8e-40 136.7 0.0 2.3e-39 134.8 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family REV1_C PF16727.5 KPA46563.1 - 4.8e-25 87.8 2.2 9.6e-25 86.8 2.2 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KPA46563.1 - 3.7e-14 53.4 0.0 1.1e-13 51.9 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 KPA46563.1 - 4.7e-13 48.1 5.0 0.001 18.4 0.0 3.9 4 0 0 4 4 4 3 Ubiquitin binding region BRCT_2 PF16589.5 KPA46563.1 - 5.6e-10 39.5 0.0 1.4e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KPA46563.1 - 0.00015 21.9 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 KPA46563.1 - 0.00024 21.4 0.0 0.00064 20.0 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain mCpol PF18182.1 KPA46563.1 - 0.00028 21.2 0.0 0.00068 20.0 0.0 1.6 1 0 0 1 1 1 1 minimal CRISPR polymerase domain DUF1805 PF08827.11 KPA46563.1 - 0.022 15.1 0.0 0.097 13.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) IMS_HHH PF11798.8 KPA46563.1 - 0.051 13.9 0.4 0.97 9.9 0.1 2.8 2 0 0 2 2 2 0 IMS family HHH motif MgtE_N PF03448.17 KPA46563.1 - 0.18 12.4 0.6 58 4.4 0.3 3.4 3 0 0 3 3 3 0 MgtE intracellular N domain WSC PF01822.19 KPA46564.1 - 3.4e-06 27.1 0.6 5.7e-06 26.4 0.6 1.3 1 0 0 1 1 1 1 WSC domain SHR3_chaperone PF08229.11 KPA46565.1 - 4.8e-77 257.2 0.0 5.4e-77 257.0 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Thymidylat_synt PF00303.19 KPA46566.1 - 9.4e-110 365.9 0.0 1.1e-109 365.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Mito_carr PF00153.27 KPA46567.1 - 6.5e-62 205.5 0.0 1.4e-20 73.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.15 KPA46568.1 - 8.2e-44 148.9 9.2 9.9e-44 148.7 9.2 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF2417 PF10329.9 KPA46568.1 - 0.041 13.3 0.4 0.051 13.0 0.4 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) AAA_22 PF13401.6 KPA46569.1 - 4.4e-15 56.2 0.0 1.2e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPA46569.1 - 6.8e-13 49.4 0.1 2.9e-12 47.3 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KPA46569.1 - 3.1e-10 40.6 0.0 1.1e-09 38.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KPA46569.1 - 1.7e-07 30.8 0.0 5.8e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Bacterial TniB protein AAA_19 PF13245.6 KPA46569.1 - 2.5e-06 27.9 0.2 3.6e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPA46569.1 - 8.4e-05 22.4 0.0 0.00036 20.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Cdc6_C PF09079.11 KPA46569.1 - 0.0001 22.2 0.0 0.00033 20.6 0.0 1.8 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 KPA46569.1 - 0.00013 22.0 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_7 PF12775.7 KPA46569.1 - 0.0014 18.2 0.0 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 KPA46569.1 - 0.004 17.0 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KPA46569.1 - 0.0067 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 KPA46569.1 - 0.0077 15.5 0.0 0.013 14.7 0.0 1.4 1 1 0 1 1 1 1 KAP family P-loop domain ATPase_2 PF01637.18 KPA46569.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KPA46569.1 - 0.015 15.7 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KPA46569.1 - 0.032 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activat PF00158.26 KPA46569.1 - 0.04 13.6 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_32 PF13654.6 KPA46569.1 - 0.043 12.6 0.0 0.079 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain SseB_C PF14581.6 KPA46569.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 SseB protein C-terminal domain AAA_5 PF07728.14 KPA46569.1 - 0.055 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 KPA46569.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_14 PF13173.6 KPA46569.1 - 0.09 12.8 0.0 0.34 11.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain DNA_pol3_delta2 PF13177.6 KPA46569.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_24 PF13479.6 KPA46569.1 - 0.19 11.4 0.0 0.45 10.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arrestin_N PF00339.29 KPA46570.1 - 2.6e-17 63.2 0.0 1.5e-16 60.7 0.0 2.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KPA46570.1 - 8e-08 32.8 0.1 2.2e-05 24.9 0.0 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain HSCB_C PF07743.13 KPA46571.1 - 2.1e-19 69.8 9.4 3.6e-19 69.0 7.3 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KPA46571.1 - 3.1e-06 27.2 0.1 6.8e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain ThiD2 PF17792.1 KPA46571.1 - 0.049 14.1 0.8 0.12 12.9 0.8 1.6 1 0 0 1 1 1 0 ThiD2 family FMN_dh PF01070.18 KPA46572.1 - 1.6e-103 346.4 0.0 2e-103 346.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KPA46572.1 - 6.1e-20 71.1 0.0 1.5e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KPA46572.1 - 3.7e-07 29.6 0.1 6.2e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KPA46572.1 - 1e-05 24.8 0.4 0.0002 20.5 0.1 2.6 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KPA46572.1 - 0.0089 15.4 0.4 0.013 14.9 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ATP11 PF06644.11 KPA46572.1 - 0.043 13.6 0.1 0.065 13.0 0.1 1.2 1 0 0 1 1 1 0 ATP11 protein His_biosynth PF00977.21 KPA46572.1 - 0.052 13.0 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 KPA46572.1 - 0.065 12.4 0.1 0.15 11.3 0.1 1.7 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Ribul_P_3_epim PF00834.19 KPA46572.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF3712 PF12505.8 KPA46573.1 - 3.7e-26 91.8 4.5 9.9e-26 90.4 3.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF1005 PF06219.12 KPA46573.1 - 0.045 12.8 0.0 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) DUF3671 PF12420.8 KPA46573.1 - 0.11 12.6 1.1 0.13 12.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function PBP1_TM PF14812.6 KPA46573.1 - 0.23 11.8 0.0 0.38 11.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HCNGP PF07818.13 KPA46574.1 - 1.1e-31 109.3 0.8 1.8e-31 108.6 0.8 1.3 1 0 0 1 1 1 1 HCNGP-like protein DEAD PF00270.29 KPA46575.1 - 5.5e-50 169.6 0.0 5.9e-49 166.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA46575.1 - 6.1e-28 97.4 0.0 2.5e-27 95.4 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CbiG_mid PF11761.8 KPA46575.1 - 0.038 14.1 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 Cobalamin biosynthesis central region SVIP PF15811.5 KPA46576.1 - 0.24 11.8 13.7 0.54 10.8 13.7 1.6 1 1 0 1 1 1 0 Small VCP/p97-interacting protein zf-H2C2_2 PF13465.6 KPA46577.1 - 9.5e-21 73.2 39.8 2.4e-07 30.9 0.1 7.9 7 1 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 KPA46577.1 - 2.5e-18 65.4 50.4 0.00017 21.8 0.8 7.4 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA46577.1 - 5.6e-16 57.9 50.1 0.0013 19.4 4.1 7.6 7 0 0 7 7 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KPA46577.1 - 1.2e-08 34.7 29.8 0.019 15.0 0.3 6.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA46577.1 - 0.00011 22.3 34.9 0.052 13.9 1.2 6.6 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding Agro_virD5 PF04730.12 KPA46577.1 - 0.00032 19.4 0.6 0.00054 18.6 0.6 1.2 1 0 0 1 1 1 1 Agrobacterium VirD5 protein zf_ZIC PF18366.1 KPA46577.1 - 0.019 15.1 0.8 0.019 15.1 0.8 2.8 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-H2C2_5 PF13909.6 KPA46577.1 - 0.19 11.5 35.3 0.11 12.3 0.7 6.3 6 0 0 6 6 5 0 C2H2-type zinc-finger domain Zip PF02535.22 KPA46577.1 - 0.45 9.7 5.8 0.83 8.8 5.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter zf-met PF12874.7 KPA46577.1 - 0.55 10.7 30.0 0.17 12.3 0.4 6.3 6 0 0 6 6 5 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KPA46577.1 - 6.6 6.7 13.2 5.2 7.1 0.6 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Ribosomal_L29 PF00831.23 KPA46578.1 - 3.4e-19 68.6 0.5 3.4e-19 68.6 0.5 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein Spc7 PF08317.11 KPA46578.1 - 0.053 12.4 2.6 0.058 12.3 2.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Vps54_N PF10475.9 KPA46578.1 - 0.087 12.1 0.7 0.097 11.9 0.7 1.1 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Phe_tRNA-synt_N PF02912.18 KPA46578.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.1 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain V-SNARE_C PF12352.8 KPA46579.1 - 2.2e-17 63.1 10.7 3.7e-15 56.0 0.7 2.9 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus RE_LlaJI PF09563.10 KPA46579.1 - 0.028 13.6 0.4 0.04 13.1 0.4 1.2 1 0 0 1 1 1 0 LlaJI restriction endonuclease DUF4337 PF14235.6 KPA46579.1 - 0.59 10.2 3.0 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) PP2C_C PF07830.13 KPA46579.1 - 2 8.9 3.8 2.3 8.7 1.2 2.3 1 1 2 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain APG6_N PF17675.1 KPA46579.1 - 2.5 8.6 10.6 0.57 10.7 5.8 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region TAP35_44 PF07265.11 KPA46579.1 - 2.9 7.9 5.2 5.5 7.0 0.2 2.7 2 1 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 DUF1451 PF07295.11 KPA46579.1 - 6.7 6.7 6.8 6.2 6.9 2.6 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain ATP-synt_10 PF05176.14 KPA46580.1 - 1.6e-77 260.2 0.0 2e-77 259.9 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein 2-oxoacid_dh PF00198.23 KPA46581.1 - 1.5e-74 250.4 0.2 2e-74 250.0 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KPA46581.1 - 9.6e-19 67.0 0.7 3.3e-18 65.3 0.2 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KPA46581.1 - 1.5e-13 50.8 0.1 4.3e-13 49.4 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain SKI PF01202.22 KPA46582.1 - 1.3e-11 44.9 0.0 1.8e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KPA46582.1 - 7.5e-11 42.7 0.1 3.8e-10 40.4 0.0 2.3 1 1 1 2 2 1 1 AAA domain AAA_33 PF13671.6 KPA46582.1 - 1.3e-09 38.3 0.0 2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KPA46582.1 - 2.3e-06 28.1 0.1 8.7e-06 26.2 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KPA46582.1 - 3.3e-06 27.1 0.0 7.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 KPA46582.1 - 2.1e-05 24.4 0.0 7.5e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase AAA_17 PF13207.6 KPA46582.1 - 3.2e-05 24.4 0.1 0.00012 22.6 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KPA46582.1 - 7.7e-05 23.1 0.0 0.00016 22.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.17 KPA46582.1 - 0.0003 20.5 0.0 0.074 12.7 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase NTPase_1 PF03266.15 KPA46582.1 - 0.00062 19.7 0.2 0.18 11.7 0.0 2.1 2 0 0 2 2 2 1 NTPase dNK PF01712.19 KPA46582.1 - 0.00065 19.6 0.0 0.047 13.5 0.0 2.3 2 1 0 2 2 2 1 Deoxynucleoside kinase Cytidylate_kin2 PF13189.6 KPA46582.1 - 0.00086 19.5 0.2 0.015 15.4 0.0 2.5 1 1 1 3 3 3 1 Cytidylate kinase-like family AAA_22 PF13401.6 KPA46582.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KPA46582.1 - 0.0025 18.1 0.2 0.0035 17.6 0.2 1.6 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 KPA46582.1 - 0.0032 17.2 0.0 0.038 13.7 0.0 2.1 2 0 0 2 2 2 1 Dephospho-CoA kinase PRK PF00485.18 KPA46582.1 - 0.0037 17.0 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KPA46582.1 - 0.0046 17.3 0.0 0.0082 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.20 KPA46582.1 - 0.0056 16.6 0.0 0.0089 15.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_14 PF13173.6 KPA46582.1 - 0.0066 16.5 0.0 0.038 14.0 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KPA46582.1 - 0.0075 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KPA46582.1 - 0.0085 15.8 0.1 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KPA46582.1 - 0.0086 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KPA46582.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KPA46582.1 - 0.012 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KPA46582.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ploopntkinase1 PF18748.1 KPA46582.1 - 0.025 14.1 0.0 3.5 7.1 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 Mg_chelatase PF01078.21 KPA46582.1 - 0.025 13.9 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KPA46582.1 - 0.048 14.2 0.0 0.091 13.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KPA46582.1 - 0.052 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KPA46582.1 - 0.057 13.1 0.1 0.091 12.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 KPA46582.1 - 0.064 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase PhoH PF02562.16 KPA46582.1 - 0.066 12.7 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 KPA46582.1 - 0.076 13.5 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KPA46582.1 - 0.078 12.7 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase PF06745.13 KPA46582.1 - 0.083 12.2 0.4 0.28 10.5 0.1 1.9 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.6 KPA46582.1 - 0.092 13.1 0.4 0.31 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KPA46582.1 - 0.095 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KPA46582.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KPA46582.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain T2SSE PF00437.20 KPA46582.1 - 0.11 11.5 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 KPA46582.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_M49 PF03571.15 KPA46583.1 - 1.4e-245 815.9 0.0 1.7e-245 815.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 DUF1104 PF06518.11 KPA46583.1 - 0.033 14.6 0.6 0.92 9.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) CdiA_C_tRNase PF18664.1 KPA46583.1 - 0.093 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain Cdh1_DBD_1 PF18196.1 KPA46583.1 - 0.11 12.8 0.3 0.32 11.3 0.2 1.7 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 LprI PF07007.12 KPA46583.1 - 0.14 12.8 0.2 0.4 11.4 0.2 1.7 1 0 0 1 1 1 0 Lysozyme inhibitor LprI Ribosomal_L6e PF01159.19 KPA46584.1 - 7.8e-40 135.9 0.3 7.8e-40 135.9 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e AAA_2 PF07724.14 KPA46585.1 - 1.1e-44 152.6 0.0 1.1e-43 149.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KPA46585.1 - 2.9e-36 123.5 2.5 2.9e-36 123.5 2.5 2.7 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KPA46585.1 - 2.9e-24 84.9 0.1 2.9e-24 84.9 0.1 2.6 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KPA46585.1 - 2.1e-19 70.2 0.0 1.9e-10 41.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KPA46585.1 - 7.6e-13 48.6 0.0 8.5e-09 35.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPA46585.1 - 1.6e-09 38.4 2.9 0.0011 19.4 0.1 4.2 2 2 2 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KPA46585.1 - 2.1e-07 30.8 0.3 0.00059 19.6 0.1 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KPA46585.1 - 2.5e-06 27.8 2.9 0.061 13.6 0.0 3.6 3 2 0 3 3 2 2 AAA domain TniB PF05621.11 KPA46585.1 - 1.2e-05 24.9 0.1 0.0049 16.3 0.1 3.7 3 1 0 3 3 2 1 Bacterial TniB protein NACHT PF05729.12 KPA46585.1 - 3.9e-05 23.6 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 KPA46585.1 - 6.6e-05 23.0 0.0 0.33 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KPA46585.1 - 0.00015 21.3 0.0 0.67 9.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KPA46585.1 - 0.00022 21.0 0.3 0.29 10.8 0.0 2.8 2 1 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.27 KPA46585.1 - 0.00073 20.1 1.6 0.26 11.8 0.0 3.4 3 0 0 3 3 3 1 ABC transporter ATPase_2 PF01637.18 KPA46585.1 - 0.0021 18.0 10.1 1.3 8.9 0.0 4.4 3 3 3 6 6 4 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KPA46585.1 - 0.0027 18.3 1.7 0.3 11.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KPA46585.1 - 0.0061 16.0 0.1 2.9 7.2 0.0 3.1 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KPA46585.1 - 0.0063 16.3 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KPA46585.1 - 0.0087 16.3 0.1 3.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KPA46585.1 - 0.0097 16.3 0.0 1.2 9.6 0.0 2.9 2 1 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KPA46585.1 - 0.01 15.4 0.3 0.16 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KPA46585.1 - 0.012 15.9 0.6 6.7 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KPA46585.1 - 0.015 15.3 0.1 10 6.1 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ERM PF00769.19 KPA46585.1 - 0.015 15.1 9.3 0.027 14.3 9.3 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ResIII PF04851.15 KPA46585.1 - 0.016 15.2 0.0 9.9 6.1 0.0 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 KPA46585.1 - 0.016 15.1 3.5 1.6 8.6 0.0 3.4 3 1 1 4 4 3 0 RsgA GTPase SRP54 PF00448.22 KPA46585.1 - 0.018 14.7 0.1 0.67 9.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KPA46585.1 - 0.02 14.6 0.0 0.6 9.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KPA46585.1 - 0.03 13.8 0.1 0.73 9.3 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein PduV-EutP PF10662.9 KPA46585.1 - 0.041 13.6 0.0 0.92 9.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 KPA46585.1 - 0.053 12.7 0.4 1.6 7.8 0.1 3.1 3 2 0 3 3 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 KPA46585.1 - 0.069 13.6 19.0 5.6 7.4 17.8 3.2 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KPA46585.1 - 0.074 13.2 0.0 18 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KPA46585.1 - 0.088 12.1 0.2 2.6 7.3 0.0 2.7 3 0 0 3 3 2 0 Zeta toxin DUF1640 PF07798.11 KPA46585.1 - 0.091 12.8 7.5 0.18 11.8 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_19 PF13245.6 KPA46585.1 - 0.13 12.5 2.3 1.1 9.6 0.1 3.0 2 2 0 3 3 3 0 AAA domain Baculo_PEP_C PF04513.12 KPA46585.1 - 0.14 12.2 0.8 0.83 9.7 0.4 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus OEP PF02321.18 KPA46585.1 - 0.15 11.8 3.9 0.35 10.7 3.9 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein CHDCT2 PF08074.11 KPA46585.1 - 0.17 12.0 2.7 0.39 10.9 2.7 1.5 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain UvrD-helicase PF00580.21 KPA46585.1 - 0.21 11.1 3.5 1 8.8 0.1 2.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Cob_adeno_trans PF01923.18 KPA46585.1 - 0.21 11.7 3.1 0.6 10.2 3.1 1.8 1 0 0 1 1 1 0 Cobalamin adenosyltransferase AAA_29 PF13555.6 KPA46585.1 - 0.23 11.2 0.3 8 6.3 0.0 2.6 3 0 0 3 3 2 0 P-loop containing region of AAA domain DNA_topoisoIV PF00521.20 KPA46585.1 - 0.24 10.3 3.5 0.38 9.6 3.5 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A CENP-F_leu_zip PF10473.9 KPA46585.1 - 0.24 11.4 16.9 1.4 9.0 16.9 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATP_bind_1 PF03029.17 KPA46585.1 - 0.33 10.7 2.2 2.9 7.6 0.0 3.1 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 KPA46585.1 - 0.35 10.6 3.7 1.8 8.3 0.0 3.4 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4061 PF13270.6 KPA46585.1 - 0.47 10.8 7.2 3.9 7.9 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) FAM76 PF16046.5 KPA46585.1 - 0.7 9.2 3.9 1.2 8.4 3.9 1.3 1 0 0 1 1 1 0 FAM76 protein GrpE PF01025.19 KPA46585.1 - 0.95 9.1 12.2 1.1 8.9 10.1 2.1 2 0 0 2 2 2 0 GrpE DUF16 PF01519.16 KPA46585.1 - 1.1 9.7 8.8 21 5.7 5.6 3.4 3 1 0 3 3 2 0 Protein of unknown function DUF16 Atg14 PF10186.9 KPA46585.1 - 1.3 8.1 8.0 2.3 7.2 8.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KPA46585.1 - 2.2 8.8 13.3 7 7.2 13.3 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 KPA46585.1 - 2.5 5.9 3.9 3.4 5.5 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.6 KPA46585.1 - 3 7.9 7.9 22 5.1 7.8 2.1 1 1 0 1 1 1 0 FlxA-like protein NPV_P10 PF05531.12 KPA46585.1 - 5.9 7.4 7.2 2.1 8.8 1.4 2.9 3 1 1 4 4 2 0 Nucleopolyhedrovirus P10 protein Arf PF00025.21 KPA46586.1 - 7.3e-80 266.5 0.2 8.6e-80 266.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KPA46586.1 - 1.6e-14 54.1 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KPA46586.1 - 2e-14 53.4 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KPA46586.1 - 2.6e-13 49.9 1.4 2.2e-09 36.9 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KPA46586.1 - 3.2e-13 49.6 0.0 3.5e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KPA46586.1 - 1.3e-10 41.0 0.0 1.7e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KPA46586.1 - 2.9e-06 27.3 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KPA46586.1 - 0.01 15.2 1.0 0.03 13.6 1.0 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase EMP24_GP25L PF01105.24 KPA46587.1 - 5.8e-46 156.7 0.0 6.6e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3405 PF11885.8 KPA46588.1 - 7.9e-229 760.5 1.4 7.9e-229 760.5 1.4 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3405) RRM_1 PF00076.22 KPA46590.1 - 2e-14 53.1 0.1 1.5e-05 24.7 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tropomodulin PF03250.14 KPA46590.1 - 0.029 14.4 0.2 0.062 13.4 0.2 1.6 1 0 0 1 1 1 0 Tropomodulin RRM_7 PF16367.5 KPA46590.1 - 0.043 13.9 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif ELL PF10390.9 KPA46590.1 - 0.046 13.2 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Proteasom_Rpn13 PF04683.13 KPA46591.1 - 1.1e-27 96.4 0.0 1.7e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KPA46591.1 - 2.1e-11 44.0 0.1 2.3e-10 40.6 0.1 2.2 1 1 0 1 1 1 1 UCH-binding domain L27_2 PF09045.10 KPA46591.1 - 0.021 14.7 0.1 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 L27_2 EF1_GNE PF00736.19 KPA46592.1 - 4.5e-33 113.3 1.4 7.4e-33 112.6 1.4 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KPA46592.1 - 5.4e-14 52.3 7.4 5.4e-14 52.3 7.4 2.7 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 KPA46592.1 - 0.00017 21.8 0.6 0.0012 19.1 0.0 2.6 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPA46592.1 - 0.00017 21.7 0.2 0.0013 18.9 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain OAD_gamma PF04277.13 KPA46592.1 - 2.9 8.6 7.1 7.7 7.2 0.7 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Sld5 PF05916.11 KPA46593.1 - 5.6e-13 49.3 0.0 7.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 KPA46593.1 - 0.1 13.5 0.0 0.72 10.7 0.0 2.3 2 0 0 2 2 2 0 Flagellar protein FliT Sulfate_transp PF00916.20 KPA46594.1 - 1.2e-54 185.6 14.5 2e-54 184.8 14.5 1.4 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KPA46594.1 - 6e-16 58.3 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KPA46594.1 - 2.3e-09 36.9 0.0 4.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain Stk19 PF10494.9 KPA46595.1 - 7.6e-62 209.2 0.0 9.2e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Kinesin PF00225.23 KPA46596.1 - 5e-94 315.0 0.0 9.3e-94 314.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPA46596.1 - 5.2e-21 75.2 0.0 4.4e-20 72.1 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 KPA46596.1 - 0.036 13.9 0.4 0.036 13.9 0.4 3.6 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TAFII55_N PF04658.13 KPA46598.1 - 3.6e-51 173.1 0.0 8.2e-51 171.9 0.0 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region FUSC PF04632.12 KPA46599.1 - 0.032 12.8 4.3 0.041 12.4 4.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HsbA PF12296.8 KPA46599.1 - 1.6 9.2 5.5 2.2 8.7 0.8 3.1 2 2 0 2 2 2 0 Hydrophobic surface binding protein A DUF1664 PF07889.12 KPA46599.1 - 1.9 8.5 5.4 1.1 9.3 1.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) OmpH PF03938.14 KPA46599.1 - 2.8 8.3 12.9 0.19 12.1 3.6 2.7 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF3074 PF11274.8 KPA46600.1 - 9.6e-42 143.0 0.7 1.3e-41 142.6 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) p450 PF00067.22 KPA46601.1 - 2.4e-73 247.5 0.0 2.9e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3045 PF11243.8 KPA46601.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) RRM_1 PF00076.22 KPA46603.1 - 8.4e-34 115.2 0.1 4.5e-16 58.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KPA46603.1 - 0.00069 19.2 0.0 0.87 9.3 0.0 2.4 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 KPA46603.1 - 0.001 19.2 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif NDUFB10 PF10249.9 KPA46604.1 - 0.0056 17.2 0.0 0.0075 16.8 0.0 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 KPA46604.1 - 0.1 13.3 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 HWE histidine kinase Ribosomal_L37 PF08561.10 KPA46605.1 - 3.2e-41 140.6 6.9 4e-41 140.3 6.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 WH2 PF02205.20 KPA46606.1 - 1.3e-09 37.6 0.8 1.3e-09 37.6 0.8 2.7 3 0 0 3 3 3 1 WH2 motif MU2_FHA PF18221.1 KPA46607.1 - 0.086 12.9 0.3 0.25 11.4 0.1 1.9 2 0 0 2 2 2 0 Mutator 2 Fork head associated domain Seryl_tRNA_N PF02403.22 KPA46611.1 - 0.015 15.5 0.4 0.036 14.3 0.4 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HLH PF00010.26 KPA46611.1 - 2.3 8.2 6.0 3.3 7.8 1.6 3.0 2 1 1 3 3 3 0 Helix-loop-helix DNA-binding domain DHR10 PF18595.1 KPA46611.1 - 2.7 8.1 7.6 9.3 6.3 7.6 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain adh_short PF00106.25 KPA46612.1 - 7.9e-14 51.6 0.0 2.2e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KPA46612.1 - 0.01 15.8 0.2 0.015 15.2 0.2 1.2 1 0 0 1 1 1 0 KR domain RhgB_N PF09284.10 KPA46613.1 - 2.8e-104 348.1 4.9 4.3e-104 347.5 4.9 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KPA46613.1 - 1.9e-40 138.4 0.0 4.6e-40 137.2 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KPA46613.1 - 5.3e-20 71.0 5.9 7.6e-20 70.5 3.3 2.6 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KPA46613.1 - 0.041 14.1 1.0 0.041 14.1 1.0 3.2 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain LELP1 PF15042.6 KPA46614.1 - 0.077 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 TMEM154 PF15102.6 KPA46615.1 - 0.00026 20.9 0.0 0.00031 20.7 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.16 KPA46615.1 - 0.033 13.0 0.0 0.034 12.9 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Na_Ca_ex PF01699.24 KPA46615.1 - 0.033 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Sodium/calcium exchanger protein EphA2_TM PF14575.6 KPA46615.1 - 0.038 14.9 0.1 0.065 14.1 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MLANA PF14991.6 KPA46615.1 - 0.18 12.1 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A Trypan_PARP PF05887.11 KPA46616.1 - 2.7 8.0 21.7 0.033 14.1 12.9 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4551 PF15087.6 KPA46616.1 - 5.2 5.8 6.9 6.5 5.5 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Annexin PF00191.20 KPA46617.1 - 1.5e-67 223.6 4.8 4.6e-19 68.2 0.0 4.2 4 0 0 4 4 4 4 Annexin DUF3574 PF12098.8 KPA46617.1 - 0.0002 21.1 0.1 2.4 8.0 0.1 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3574) BTB PF00651.31 KPA46619.1 - 0.018 15.3 0.0 0.048 13.9 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain DUF1199 PF06712.11 KPA46619.1 - 1.7 8.8 5.9 13 5.9 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) Ppx-GppA PF02541.16 KPA46621.1 - 1.1e-24 87.4 0.0 2.5e-24 86.2 0.0 1.5 1 1 0 1 1 1 1 Ppx/GppA phosphatase family zf-Mss51 PF13824.6 KPA46622.1 - 1.7 8.8 5.3 19 5.4 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Aldedh PF00171.22 KPA46625.1 - 2.2e-183 610.0 0.1 2.5e-183 609.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_12 PF13087.6 KPA46627.1 - 3.3e-14 53.0 0.1 5.8e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain SNF2_N PF00176.23 KPA46628.1 - 6.6e-39 133.6 0.0 3.5e-35 121.4 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 KPA46628.1 - 0.0007 19.6 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit F-box-like PF12937.7 KPA46629.1 - 0.0066 16.3 0.0 0.026 14.4 0.0 2.1 1 0 0 1 1 1 1 F-box-like Zn_clus PF00172.18 KPA46631.1 - 0.0019 18.3 4.3 0.0044 17.1 4.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HECT_2 PF09814.9 KPA46632.1 - 2.3e-107 359.1 1.4 2.6e-107 358.9 1.4 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GFA PF04828.14 KPA46632.1 - 0.026 14.9 0.2 0.62 10.4 0.1 2.5 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DNA_RNApol_7kD PF03604.13 KPA46632.1 - 0.62 9.8 3.2 0.96 9.2 0.1 2.7 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Questin_oxidase PF14027.6 KPA46633.1 - 2.4e-90 303.5 0.4 2.9e-90 303.3 0.4 1.1 1 0 0 1 1 1 1 Questin oxidase-like DUF3885 PF13021.6 KPA46633.1 - 0.23 11.6 0.2 0.23 11.6 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3885) Rad17 PF03215.15 KPA46634.1 - 6.8e-25 88.1 0.0 1.7e-24 86.8 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KPA46634.1 - 0.001 19.5 0.0 0.0082 16.6 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPA46634.1 - 0.0011 19.4 0.4 0.0037 17.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPA46634.1 - 0.0043 17.3 0.2 0.015 15.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPA46634.1 - 0.005 16.6 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KPA46634.1 - 0.037 14.0 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KPA46634.1 - 0.037 13.9 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 KPA46634.1 - 0.063 13.0 0.1 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KPA46634.1 - 0.068 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 KPA46634.1 - 0.11 12.7 0.1 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AICARFT_IMPCHas PF01808.18 KPA46635.1 - 1.8e-92 310.0 0.0 2.4e-92 309.6 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KPA46635.1 - 1.3e-22 79.8 0.0 2.4e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Lactamase_B_2 PF12706.7 KPA46635.1 - 0.033 13.7 0.0 5.6 6.4 0.0 2.8 3 0 0 3 3 3 0 Beta-lactamase superfamily domain Lipase_GDSL_2 PF13472.6 KPA46636.1 - 7.8e-16 59.0 0.0 9.4e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPA46636.1 - 6.6e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fungal_trans PF04082.18 KPA46638.1 - 5.9e-12 45.2 1.4 1e-11 44.4 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA46638.1 - 3.1e-07 30.4 8.4 6.9e-07 29.3 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4516 PF14990.6 KPA46638.1 - 0.21 11.4 1.1 0.44 10.3 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) MARVEL PF01284.23 KPA46639.1 - 0.013 15.6 1.0 0.013 15.6 1.0 2.9 2 1 1 3 3 3 0 Membrane-associating domain Ank_4 PF13637.6 KPA46640.1 - 5.2e-38 128.9 5.7 2.4e-06 27.9 0.0 7.9 8 1 1 9 9 9 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPA46640.1 - 7.9e-34 116.1 2.2 1e-06 29.2 0.0 7.0 4 2 4 8 8 8 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPA46640.1 - 2e-27 92.2 7.7 0.001 19.3 0.0 11.7 12 1 0 12 12 12 6 Ankyrin repeat Ank PF00023.30 KPA46640.1 - 7e-26 89.5 21.2 3.8e-05 23.9 0.2 10.6 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 KPA46640.1 - 2.2e-22 78.8 4.9 6.2e-07 29.6 0.0 7.2 6 1 1 7 7 7 5 Ankyrin repeats (many copies) DUF2470 PF10615.9 KPA46641.1 - 1.9e-22 79.7 0.1 2.5e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 KPA46641.1 - 0.075 13.4 1.6 0.15 12.4 1.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4499) zf-C2H2_2 PF12756.7 KPA46642.1 - 0.004 17.5 0.7 0.01 16.2 0.7 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KPA46642.1 - 0.12 13.2 3.4 1.9 9.6 0.8 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KPA46642.1 - 0.18 11.6 6.9 0.074 12.8 2.1 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type CDC45 PF02724.14 KPA46642.1 - 0.84 7.9 8.2 1.2 7.3 8.2 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2 PF00096.26 KPA46642.1 - 2.7 8.6 4.7 0.61 10.6 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type F-protein PF00469.20 KPA46642.1 - 3.1 7.3 7.4 7.2 6.1 7.4 1.6 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef UBN_AB PF14075.6 KPA46642.1 - 6.6 6.4 12.4 0.054 13.2 3.2 2.2 3 0 0 3 3 3 0 Ubinuclein conserved middle domain Tetraspanin PF00335.20 KPA46643.1 - 3.9e-07 30.0 0.0 7.1e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 Tetraspanin family Pox_A14 PF05767.12 KPA46643.1 - 0.11 12.7 0.6 0.38 10.9 0.2 1.9 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DEAD PF00270.29 KPA46644.1 - 1.9e-32 112.5 0.0 1.9e-16 60.3 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA46644.1 - 2.9e-21 75.9 0.0 6.1e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA46644.1 - 3.2e-07 30.5 0.0 3.2e-07 30.5 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PIGA PF08288.12 KPA46645.1 - 4.7e-47 158.5 3.5 5.4e-47 158.3 1.0 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KPA46645.1 - 4.2e-28 98.5 0.7 6.4e-28 97.9 0.7 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KPA46645.1 - 3.5e-27 95.0 0.0 5.4e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KPA46645.1 - 2.5e-22 79.7 0.1 5.4e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KPA46645.1 - 5.6e-14 52.9 0.0 9.1e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KPA46645.1 - 0.00041 20.4 0.1 0.00074 19.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KPA46645.1 - 0.003 17.9 0.0 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KPA46645.1 - 0.17 11.5 0.0 0.4 10.3 0.0 1.6 2 0 0 2 2 2 0 Starch synthase catalytic domain Bromodomain PF00439.25 KPA46646.1 - 0.00017 21.6 0.0 0.00072 19.6 0.0 2.0 1 1 0 1 1 1 1 Bromodomain WD40 PF00400.32 KPA46647.1 - 5.6e-14 52.3 6.8 0.0029 18.4 0.1 8.1 8 0 0 8 8 8 3 WD domain, G-beta repeat WD40_like PF17005.5 KPA46647.1 - 0.0036 16.7 0.2 0.12 11.7 0.1 2.8 3 0 0 3 3 3 1 WD40-like domain ANAPC4_WD40 PF12894.7 KPA46647.1 - 0.0045 17.3 0.0 24 5.3 0.0 4.6 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KPA46647.1 - 0.0061 16.2 0.0 3.4 7.2 0.0 3.0 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 KPA46647.1 - 0.49 11.0 5.6 2.2 8.9 0.1 4.4 4 0 0 4 4 4 0 PQQ-like domain Hamartin PF04388.12 KPA46647.1 - 3.7 6.1 8.4 9.2 4.8 8.4 1.6 2 0 0 2 2 2 0 Hamartin protein Rgp1 PF08737.10 KPA46648.1 - 5.4e-157 523.2 0.0 8.9e-157 522.5 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 KPA46648.1 - 0.0011 19.1 0.0 0.0036 17.4 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KPA46648.1 - 0.049 14.1 0.0 0.29 11.6 0.0 2.2 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain DUF1776 PF08643.10 KPA46651.1 - 1.2e-102 343.3 0.0 1.5e-102 343.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) zf-CCCH PF00642.24 KPA46652.1 - 3.3e-23 81.1 32.5 2.5e-08 33.6 0.6 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KPA46652.1 - 9.1e-21 73.2 35.6 3.7e-06 26.8 3.1 5.3 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 KPA46652.1 - 1.4e-11 45.0 25.6 0.00035 21.2 0.8 5.6 1 1 5 6 6 6 5 Torus domain zf-CCCH_4 PF18044.1 KPA46652.1 - 3.3e-08 33.2 36.9 9.2e-06 25.3 1.4 5.2 5 0 0 5 5 5 4 CCCH-type zinc finger GRP PF07172.11 KPA46652.1 - 0.18 12.5 8.6 0.28 11.9 8.6 1.3 1 0 0 1 1 1 0 Glycine rich protein family zf-CCCH_3 PF15663.5 KPA46652.1 - 1.1 9.5 18.2 0.12 12.6 2.8 3.4 1 1 2 3 3 3 0 Zinc-finger containing family Methyltransf_23 PF13489.6 KPA46653.1 - 3.1e-08 33.6 0.0 4.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPA46653.1 - 1e-06 29.3 0.0 6.8e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPA46653.1 - 9.4e-05 23.1 0.1 0.00057 20.6 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPA46653.1 - 0.0004 20.2 0.3 0.0019 18.0 0.1 2.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPA46653.1 - 0.00067 20.3 0.0 0.0017 18.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPA46653.1 - 0.0045 16.5 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KPA46653.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 KPA46653.1 - 0.019 14.7 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase GidB PF02527.15 KPA46653.1 - 0.04 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.17 KPA46653.1 - 0.055 12.9 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 KPA46653.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KPA46653.1 - 0.2 10.9 0.0 0.51 9.6 0.0 1.7 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase Glyco_hydro_18 PF00704.28 KPA46654.1 - 1.2e-66 225.6 0.0 1.3e-66 225.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Syntaxin PF00804.25 KPA46656.1 - 2.5e-19 69.7 15.2 2.5e-19 69.7 15.2 2.0 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 KPA46656.1 - 9.9e-13 47.9 0.7 9.9e-13 47.9 0.7 2.8 2 1 1 3 3 3 1 SNARE domain Use1 PF09753.9 KPA46656.1 - 5.1e-05 23.1 7.8 5.1e-05 23.1 7.8 1.6 1 1 1 2 2 2 1 Membrane fusion protein Use1 ODV-E18 PF10717.9 KPA46656.1 - 0.0018 18.1 1.1 0.0018 18.1 1.1 2.3 3 0 0 3 3 3 1 Occlusion-derived virus envelope protein ODV-E18 Mid2 PF04478.12 KPA46656.1 - 0.0023 17.8 0.5 0.0046 16.8 0.5 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Chordopox_A33R PF05966.12 KPA46656.1 - 0.0026 17.1 0.9 0.07 12.4 0.2 2.3 2 0 0 2 2 2 1 Chordopoxvirus A33R protein Mod_r PF07200.13 KPA46656.1 - 0.0031 17.6 14.0 0.14 12.3 2.7 2.5 2 1 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein DUF5385 PF17359.2 KPA46656.1 - 0.0037 16.8 1.0 0.0037 16.8 1.0 2.4 3 0 0 3 3 3 1 Family of unknown function (DUF5385) Sigma_reg_N PF13800.6 KPA46656.1 - 0.026 14.8 0.7 0.053 13.8 0.7 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3671 PF12420.8 KPA46656.1 - 0.03 14.4 0.2 0.056 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function Ac76 PF05814.11 KPA46656.1 - 0.034 14.1 0.2 0.085 12.9 0.2 1.7 1 0 0 1 1 1 0 Orf76 (Ac76) AA_permease_2 PF13520.6 KPA46656.1 - 0.038 12.8 0.8 0.049 12.5 0.8 1.1 1 0 0 1 1 1 0 Amino acid permease DUF3357 PF11837.8 KPA46656.1 - 0.038 14.4 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Allexi_40kDa PF05549.11 KPA46656.1 - 0.06 12.9 8.3 0.068 12.7 1.6 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein SBF_like PF13593.6 KPA46656.1 - 0.071 12.4 0.3 0.1 11.9 0.3 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) 7tm_7 PF08395.12 KPA46656.1 - 0.089 12.0 0.1 0.089 12.0 0.1 2.5 3 0 0 3 3 3 0 7tm Chemosensory receptor Chordopox_A13L PF05961.11 KPA46656.1 - 0.12 12.7 1.2 0.4 10.9 1.2 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein EphA2_TM PF14575.6 KPA46656.1 - 0.15 12.9 0.4 0.15 12.9 0.4 2.0 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain TMCO5 PF14992.6 KPA46656.1 - 0.25 10.9 11.2 22 4.5 11.2 2.2 1 1 0 1 1 1 0 TMCO5 family AnkUBD PF18418.1 KPA46656.1 - 0.37 11.0 3.3 0.37 11.0 0.1 2.4 2 1 1 3 3 3 0 Ankyrin ubiquitin-binding domain DUF4094 PF13334.6 KPA46656.1 - 0.55 10.7 4.6 1.4 9.4 1.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Orf78 PF06024.12 KPA46656.1 - 0.81 10.0 13.3 0.084 13.2 6.9 2.6 2 1 1 3 3 3 0 Orf78 (ac78) V-SNARE PF05008.15 KPA46656.1 - 1.6 9.2 15.9 0.22 11.9 1.8 4.2 2 2 2 4 4 4 0 Vesicle transport v-SNARE protein N-terminus CRA PF06589.11 KPA46656.1 - 2.2 8.4 7.9 0.95 9.6 4.5 2.0 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) Prominin PF05478.11 KPA46656.1 - 2.3 6.1 13.2 0.15 10.0 4.8 1.9 1 1 0 2 2 2 0 Prominin Baculo_11_kDa PF06143.11 KPA46656.1 - 2.5 7.7 6.9 0.16 11.6 0.7 2.2 3 0 0 3 3 3 0 Baculovirus 11 kDa family T2SSF PF00482.23 KPA46656.1 - 5.6 6.9 7.9 1.4e+02 2.4 6.4 3.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F COG2 PF06148.11 KPA46656.1 - 6.2 6.9 7.9 0.92 9.6 0.9 2.9 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Memo PF01875.17 KPA46657.1 - 5.4e-74 248.7 0.0 6.3e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein SesA PF17107.5 KPA46658.1 - 0.0012 19.0 0.3 0.0021 18.3 0.3 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_2 PF12796.7 KPA46658.1 - 0.0031 18.1 0.0 0.015 15.8 0.0 2.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA46658.1 - 0.028 14.7 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA46658.1 - 0.029 14.9 0.5 0.13 12.9 0.1 2.5 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 KPA46658.1 - 0.14 12.8 0.0 1 10.0 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Cation_efflux PF01545.21 KPA46659.1 - 2.8e-50 170.8 12.0 9.6e-50 169.1 12.0 1.7 1 1 0 1 1 1 1 Cation efflux family DUF3395 PF11875.8 KPA46660.1 - 2.8e-23 82.5 0.3 9.3e-23 80.9 0.0 2.0 2 0 0 2 2 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KPA46660.1 - 1.9e-11 43.9 0.4 4.6e-11 42.7 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain Mpp10 PF04006.12 KPA46660.1 - 0.00057 18.5 10.9 0.00074 18.1 10.9 1.1 1 0 0 1 1 1 1 Mpp10 protein RRN3 PF05327.11 KPA46660.1 - 0.0021 16.7 13.7 0.0029 16.2 13.7 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 KPA46660.1 - 0.0037 15.6 13.2 0.006 14.9 13.2 1.3 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 KPA46660.1 - 0.039 12.2 26.1 0.055 11.7 26.1 1.1 1 0 0 1 1 1 0 Nop14-like family PT PF04886.12 KPA46660.1 - 0.1 12.2 3.8 0.33 10.5 3.8 1.9 1 0 0 1 1 1 0 PT repeat SDA1 PF05285.12 KPA46660.1 - 0.15 11.4 22.5 0.24 10.8 22.5 1.2 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.8 KPA46660.1 - 0.23 10.4 11.2 0.35 9.8 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PPP4R2 PF09184.11 KPA46660.1 - 0.61 9.6 18.8 1 8.9 18.8 1.3 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 KPA46660.1 - 2.6 6.1 36.9 3.9 5.4 36.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KPA46660.1 - 3 7.1 27.1 6.1 6.1 27.1 1.5 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 KPA46660.1 - 4.4 7.2 23.6 0.75 9.7 19.7 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pox_Ag35 PF03286.14 KPA46660.1 - 5.4 6.8 13.9 12 5.6 13.9 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.12 KPA46660.1 - 5.9 6.2 23.4 10 5.4 23.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.13 KPA46660.1 - 9.9 6.0 21.2 22 4.8 21.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Ig_6 PF18452.1 KPA46661.1 - 0.28 10.8 1.3 10 5.8 0.3 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Cyclin_N PF00134.23 KPA46662.1 - 9e-39 132.1 0.1 4.8e-38 129.8 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KPA46662.1 - 6.1e-11 42.4 0.0 2.2e-10 40.6 0.0 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain MOSC PF03473.17 KPA46663.1 - 1.2e-14 54.4 0.0 1.8e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 MOSC domain Ribonuc_L-PSP PF01042.21 KPA46665.1 - 7.9e-10 38.8 0.0 1.3e-09 38.1 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP MbeB_N PF04837.12 KPA46665.1 - 0.14 12.5 0.1 0.24 11.8 0.1 1.3 1 0 0 1 1 1 0 MbeB-like, N-term conserved region adh_short PF00106.25 KPA46666.1 - 7.2e-24 84.3 0.0 8.1e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA46666.1 - 1.2e-12 47.9 0.0 1.5e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPA46666.1 - 7.6e-06 25.6 0.0 9.2e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPA46666.1 - 6.1e-05 23.0 0.0 7.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 KR domain GCIP PF13324.6 KPA46666.1 - 0.094 12.3 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting MRFAP1 PF15155.6 KPA46667.1 - 0.094 13.2 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 MORF4 family-associated protein1 DLH PF01738.18 KPA46668.1 - 1.2e-23 83.9 0.0 1.3e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KPA46668.1 - 0.057 12.9 0.0 0.29 10.6 0.0 1.8 1 1 1 2 2 2 0 Prolyl oligopeptidase family 3HCDH_N PF02737.18 KPA46669.1 - 6.4e-40 137.0 0.0 1.5e-39 135.7 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KPA46669.1 - 1.4e-09 38.4 0.0 2.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.25 KPA46669.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 KPA46669.1 - 0.0027 17.1 0.0 0.0057 16.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KPA46669.1 - 0.047 13.9 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short_C2 PF13561.6 KPA46669.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF29 PF01724.16 KPA46669.1 - 0.15 12.3 0.4 0.55 10.5 0.4 1.9 3 0 0 3 3 3 0 Domain of unknown function DUF29 CoA_transf_3 PF02515.17 KPA46670.1 - 1.2e-33 116.8 0.0 8e-32 110.8 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III FAD_binding_3 PF01494.19 KPA46671.1 - 4.2e-18 65.7 0.5 2.5e-17 63.1 0.5 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPA46671.1 - 1.3e-05 25.3 0.3 4.2e-05 23.7 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPA46671.1 - 0.00017 20.9 0.6 0.00035 19.9 0.5 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPA46671.1 - 0.0021 17.7 0.3 0.0041 16.7 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPA46671.1 - 0.0045 16.1 0.6 0.0074 15.4 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KPA46671.1 - 0.0069 15.7 0.1 0.17 11.2 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KPA46671.1 - 0.019 15.5 0.9 0.075 13.6 0.8 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KPA46671.1 - 0.058 12.4 0.0 0.24 10.4 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase OAD_beta PF03977.13 KPA46671.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit Amidase PF01425.21 KPA46672.1 - 6e-106 355.1 0.0 8e-106 354.7 0.0 1.2 1 0 0 1 1 1 1 Amidase RGS PF00615.19 KPA46673.1 - 7.4e-37 126.2 0.2 2.2e-36 124.7 0.1 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KPA46673.1 - 2e-22 79.0 0.0 9.6e-19 67.2 0.0 3.3 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.6 KPA46673.1 - 0.031 14.3 0.1 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Replication-relaxation Flocculin_t3 PF13928.6 KPA46674.1 - 0.0071 16.8 4.8 0.0071 16.8 4.8 2.4 2 1 0 2 2 2 1 Flocculin type 3 repeat ORC4_C PF14629.6 KPA46676.1 - 1.9e-67 226.8 0.0 2.7e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus PHD_2 PF13831.6 KPA46676.1 - 1.2e-12 47.2 1.6 1.2e-12 47.2 1.6 1.6 2 0 0 2 2 1 1 PHD-finger AAA_16 PF13191.6 KPA46676.1 - 1.3e-12 48.4 0.1 4.4e-12 46.7 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain PHD PF00628.29 KPA46676.1 - 9.8e-11 41.4 7.0 1.6e-10 40.7 7.0 1.4 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.6 KPA46676.1 - 3.3e-09 37.1 0.0 6.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KPA46676.1 - 4.1e-07 30.5 0.0 9.4e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KPA46676.1 - 5.8e-07 29.6 0.0 2e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KPA46676.1 - 5.4e-05 23.6 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain FYVE_2 PF02318.16 KPA46676.1 - 7.5e-05 22.9 1.2 0.00016 21.9 1.2 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger KAP_NTPase PF07693.14 KPA46676.1 - 8.7e-05 21.9 0.0 0.00027 20.3 0.0 1.6 1 1 1 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.22 KPA46676.1 - 9.5e-05 21.7 0.1 0.00015 21.1 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KPA46676.1 - 0.00025 20.8 0.0 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KPA46676.1 - 0.00027 21.0 0.0 0.0007 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KPA46676.1 - 0.00028 20.9 0.0 0.00061 19.8 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea TniB PF05621.11 KPA46676.1 - 0.00078 18.9 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein ATP-synt_ab PF00006.25 KPA46676.1 - 0.0041 16.8 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.27 KPA46676.1 - 0.0087 16.6 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter C1_1 PF00130.22 KPA46676.1 - 0.0095 15.8 0.3 0.02 14.8 0.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF815 PF05673.13 KPA46676.1 - 0.022 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MobB PF03205.14 KPA46676.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 KPA46676.1 - 0.055 13.7 0.1 0.21 11.8 0.0 2.0 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KPA46676.1 - 0.073 13.5 0.0 0.25 11.7 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Prok-RING_1 PF14446.6 KPA46676.1 - 0.082 12.8 3.2 0.23 11.4 3.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 AAA_33 PF13671.6 KPA46676.1 - 0.097 12.8 0.3 0.34 11.0 0.1 2.1 2 1 0 2 2 1 0 AAA domain PIF1 PF05970.14 KPA46676.1 - 0.099 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_7 PF12775.7 KPA46676.1 - 0.11 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KPA46676.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KPA46676.1 - 0.14 11.3 0.0 1.8 7.6 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Viral_helicase1 PF01443.18 KPA46676.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.9 KPA46676.1 - 0.17 10.8 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 KPA46676.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KPA46676.1 - 0.18 11.7 0.0 0.47 10.3 0.0 1.7 2 0 0 2 2 2 0 NTPase C1_2 PF03107.16 KPA46676.1 - 0.2 12.0 4.6 0.079 13.3 1.4 1.9 2 0 0 2 2 2 0 C1 domain zf-PHD-like PF15446.6 KPA46676.1 - 0.41 10.3 2.4 0.71 9.5 2.4 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.6 KPA46676.1 - 5.7 7.4 6.7 11 6.4 6.7 1.5 1 0 0 1 1 1 0 Ring finger domain LtrA PF06772.11 KPA46677.1 - 5.8e-19 68.5 19.3 5.8e-19 68.5 19.3 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) DUF2157 PF09925.9 KPA46677.1 - 5.6 6.7 13.3 0.55 10.0 2.5 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) ASXH PF13919.6 KPA46678.1 - 1e-39 135.7 0.9 2e-39 134.8 0.9 1.5 1 0 0 1 1 1 1 Asx homology domain UPF0172 PF03665.13 KPA46678.1 - 0.6 10.1 4.8 0.17 11.9 0.7 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) DUF2264 PF10022.9 KPA46679.1 - 6.2e-135 449.8 0.2 7.6e-135 449.5 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Sugar_tr PF00083.24 KPA46680.1 - 3.1e-120 402.1 26.5 3.7e-120 401.8 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA46680.1 - 1.4e-21 76.8 28.5 1.4e-21 76.8 28.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRAPPC9-Trs120 PF08626.11 KPA46682.1 - 0 1431.1 0.0 0 1430.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit adh_short PF00106.25 KPA46682.1 - 1.5e-20 73.5 0.0 2.8e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPA46682.1 - 1.3e-15 57.7 0.0 2.3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPA46682.1 - 0.16 11.8 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 KR domain Aldo_ket_red PF00248.21 KPA46683.1 - 1.1e-44 152.8 0.0 2.3e-43 148.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family XRCC4 PF06632.12 KPA46684.1 - 5.5e-09 35.3 8.2 7.7e-09 34.9 8.2 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 SPATA24 PF15175.6 KPA46684.1 - 0.018 14.9 0.6 0.018 14.9 0.6 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 Methyltr_RsmF_N PF17125.5 KPA46684.1 - 0.023 15.2 0.0 0.076 13.5 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF Chal_sti_synt_N PF00195.19 KPA46684.1 - 0.11 11.8 0.4 0.19 11.1 0.4 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Arg_decarbox_C PF17944.1 KPA46684.1 - 0.3 11.7 1.2 0.81 10.3 1.2 1.7 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension Tis11B_N PF04553.12 KPA46685.1 - 8.7 6.9 7.0 1.8 9.2 0.3 2.9 2 0 0 2 2 2 0 Tis11B like protein, N terminus Methyltr_RsmB-F PF01189.17 KPA46686.1 - 5.7e-76 254.6 0.0 1e-75 253.8 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KPA46686.1 - 7.1e-08 32.8 0.0 2e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF PCMT PF01135.19 KPA46686.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2431 PF10354.9 KPA46686.1 - 0.023 15.0 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_25 PF13649.6 KPA46686.1 - 0.038 14.7 0.0 0.1 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KPA46686.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Blt1 PF12754.7 KPA46687.1 - 1.7e-38 132.3 0.7 2.3e-38 131.9 0.7 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KPA46687.1 - 2.5e-19 68.6 0.2 3.9e-19 68.0 0.2 1.3 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 KPA46687.1 - 1.5e-05 24.6 0.1 2.3e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Cofilin_ADF PF00241.20 KPA46688.1 - 3.2e-39 133.5 0.5 3.7e-39 133.3 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.24 KPA46689.1 - 2.5e-86 290.3 10.8 6.6e-86 288.9 10.8 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3552 PF12072.8 KPA46690.1 - 1.8 7.9 26.4 0.29 10.5 11.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) rRNA_processing PF08524.11 KPA46691.1 - 0.012 15.6 13.2 0.018 15.1 13.2 1.3 1 0 0 1 1 1 0 rRNA processing RNA_polI_A34 PF08208.11 KPA46691.1 - 0.14 12.2 19.4 0.18 11.9 19.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 ORC6 PF05460.13 KPA46691.1 - 0.36 10.0 12.4 0.38 10.0 12.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TLP-20 PF06088.11 KPA46691.1 - 0.44 10.4 3.9 0.52 10.2 3.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RR_TM4-6 PF06459.12 KPA46691.1 - 0.52 10.1 14.1 0.62 9.8 14.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 KPA46691.1 - 1.7 7.5 5.4 2 7.3 5.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SRP-alpha_N PF04086.13 KPA46691.1 - 2.2 8.1 15.3 2.3 8.0 15.3 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Consortin_C PF15281.6 KPA46691.1 - 2.4 8.2 3.4 4.5 7.3 3.4 1.4 1 0 0 1 1 1 0 Consortin C-terminus DUF5427 PF10310.9 KPA46691.1 - 5.1 5.9 14.7 5.2 5.9 14.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) MCM_bind PF09739.9 KPA46691.1 - 6.3 5.1 6.9 6.3 5.1 6.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor FancD2 PF14631.6 KPA46691.1 - 6.6 4.0 8.3 7 3.9 8.3 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease NPR3 PF03666.13 KPA46691.1 - 7.1 5.3 10.0 7.5 5.2 10.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4551 PF15087.6 KPA46691.1 - 7.6 5.2 7.9 7.9 5.2 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 KPA46691.1 - 9.5 4.4 9.7 11 4.2 9.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4677 PF15726.5 KPA46692.1 - 0.0038 17.4 0.6 0.0041 17.3 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4677) VIR_N PF15912.5 KPA46692.1 - 0.022 14.4 2.8 0.027 14.1 2.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Med3 PF11593.8 KPA46692.1 - 0.07 12.3 2.0 0.078 12.2 2.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Astro_capsid_p PF12226.8 KPA46692.1 - 0.076 12.2 4.3 0.084 12.0 4.3 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ORC6 PF05460.13 KPA46693.1 - 0.25 10.6 3.8 0.31 10.3 3.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Myb_DNA-bind_4 PF13837.6 KPA46695.1 - 2.3e-05 24.7 0.2 0.59 10.6 0.0 3.4 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain HTH_12 PF08461.10 KPA46695.1 - 0.0025 17.7 0.0 3.6 7.6 0.0 3.7 4 0 0 4 4 4 1 Ribonuclease R winged-helix domain TFIIA PF03153.13 KPA46695.1 - 6.6 6.6 33.0 1.1 9.2 27.4 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ORC6 PF05460.13 KPA46696.1 - 0.042 13.1 2.9 0.048 12.9 2.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DTHCT PF08070.11 KPA46696.1 - 0.049 14.4 12.1 0.095 13.4 12.1 1.5 1 0 0 1 1 1 0 DTHCT (NUC029) region DUF1770 PF08589.10 KPA46696.1 - 3.6 8.6 7.0 8.1 7.5 7.0 1.7 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Ribosomal_60s PF00428.19 KPA46696.1 - 6.5 7.4 11.9 0.39 11.3 1.0 2.4 1 1 1 2 2 2 0 60s Acidic ribosomal protein UFD1 PF03152.14 KPA46697.1 - 4.2e-67 225.0 0.0 5.3e-67 224.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 GYF PF02213.16 KPA46698.1 - 8.5e-09 35.0 2.1 2.2e-08 33.6 2.1 1.7 1 0 0 1 1 1 1 GYF domain Gluconate_2-dh3 PF13618.6 KPA46698.1 - 0.59 10.4 8.0 0.1 12.8 2.5 2.3 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Gp_dh_C PF02800.20 KPA46699.1 - 8.5e-73 243.2 0.0 1.3e-72 242.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KPA46699.1 - 3.3e-39 133.3 0.3 8.9e-39 131.9 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KPA46699.1 - 0.0038 17.4 0.5 0.015 15.4 0.2 2.3 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 KPA46699.1 - 0.052 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPA46699.1 - 0.08 12.3 0.1 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TFIIE-A_C PF11521.8 KPA46700.1 - 2.3 8.6 7.7 11 6.4 7.7 2.2 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Spore_YpjB PF09577.10 KPA46701.1 - 0.0042 16.9 2.7 0.0042 16.9 2.7 2.9 2 0 0 2 2 2 1 Sporulation protein YpjB (SpoYpjB) DUF1441 PF07278.11 KPA46701.1 - 0.024 14.6 3.6 0.068 13.1 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) DUF3660 PF12398.8 KPA46701.1 - 0.095 12.8 1.5 0.34 11.0 1.5 1.9 1 0 0 1 1 1 0 Receptor serine/threonine kinase DUF3287 PF11690.8 KPA46701.1 - 0.29 10.9 3.5 13 5.5 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) Trimer_CC PF08954.11 KPA46701.1 - 0.37 10.4 0.0 0.11 12.0 0.5 5.5 6 1 0 6 6 6 0 Trimerisation motif Tropomyosin_1 PF12718.7 KPA46701.1 - 2.2 8.4 55.4 0.51 10.5 8.4 6.0 4 1 1 5 5 5 0 Tropomyosin like TIP49 PF06068.13 KPA46702.1 - 6e-154 512.5 1.4 7.8e-154 512.1 1.4 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KPA46702.1 - 1.5e-21 76.3 0.1 8.4e-21 73.9 0.1 2.4 3 0 0 3 3 3 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KPA46702.1 - 1.1e-08 34.9 0.4 7.2e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KPA46702.1 - 6.9e-08 33.0 0.9 6.3e-05 23.4 0.1 3.0 1 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KPA46702.1 - 6.7e-07 28.9 1.3 1.4e-06 27.8 1.3 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KPA46702.1 - 4.1e-06 27.3 0.1 1e-05 26.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KPA46702.1 - 0.0013 18.2 1.0 0.023 14.1 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KPA46702.1 - 0.0036 17.3 0.3 1.9 8.5 0.0 3.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPA46702.1 - 0.0047 17.2 0.0 0.74 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KPA46702.1 - 0.0088 15.8 0.1 3.6 7.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 KPA46702.1 - 0.0092 16.3 1.4 0.48 10.7 1.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPA46702.1 - 0.022 14.6 1.6 0.29 10.9 1.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KPA46702.1 - 0.032 13.8 0.1 0.068 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KPA46702.1 - 0.051 12.7 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 KPA46702.1 - 0.057 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KPA46702.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KPA46702.1 - 0.11 12.0 0.2 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DJ-1_PfpI PF01965.24 KPA46703.1 - 2.2e-14 53.6 0.0 3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HLH PF00010.26 KPA46704.1 - 7.2e-08 32.3 0.2 5.6e-07 29.4 0.0 2.5 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain ORC6 PF05460.13 KPA46704.1 - 0.28 10.4 10.7 0.45 9.7 10.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MTBP_C PF14920.6 KPA46704.1 - 2.9 7.6 10.3 5.3 6.7 10.3 1.5 1 0 0 1 1 1 0 MDM2-binding PRIMA1 PF16101.5 KPA46704.1 - 3.4 7.7 11.6 0.58 10.2 0.9 3.1 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 TMEM135_C_rich PF15982.5 KPA46705.1 - 0.00027 21.5 1.2 0.002 18.7 1.2 2.2 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 GET2 PF08690.10 KPA46706.1 - 3.2e-48 165.0 0.0 4e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 DUF350 PF03994.14 KPA46706.1 - 0.089 13.0 1.0 0.49 10.6 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) Pex19 PF04614.12 KPA46706.1 - 0.17 11.6 0.5 0.35 10.6 0.1 1.8 2 0 0 2 2 2 0 Pex19 protein family Sec16_C PF12931.7 KPA46707.1 - 2e-11 44.1 0.3 4e-10 39.9 0.1 2.7 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 KPA46707.1 - 8.1e-10 38.7 0.0 8.1e-10 38.7 0.0 3.7 2 1 1 3 3 3 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 KPA46707.1 - 3e-07 31.0 0.6 0.067 14.1 0.0 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat Sec16 PF12932.7 KPA46707.1 - 7.1e-05 23.4 0.2 0.00031 21.3 0.2 2.1 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region ANAPC4_WD40 PF12894.7 KPA46707.1 - 0.00086 19.6 0.2 0.4 11.0 0.2 3.2 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 KPA46707.1 - 0.015 15.2 0.1 2.5 8.1 0.0 3.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal PALB2_WD40 PF16756.5 KPA46707.1 - 0.032 13.1 0.0 0.15 11.0 0.0 1.9 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain RRM_1 PF00076.22 KPA46708.1 - 1.8e-15 56.5 0.0 2.3e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPA46708.1 - 0.0045 17.0 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KPA46708.1 - 0.007 16.5 0.0 0.0092 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 KPA46708.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.3 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KPA46708.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) B12D PF06522.11 KPA46709.1 - 0.0003 20.5 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit ThrE PF06738.12 KPA46709.1 - 0.18 11.1 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter COX6B PF02297.17 KPA46710.1 - 8.6e-18 64.3 4.6 9.8e-18 64.2 4.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KPA46710.1 - 0.028 14.4 1.5 0.047 13.7 1.5 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 KPA46710.1 - 0.049 13.6 1.5 0.055 13.4 0.9 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 KPA46710.1 - 0.22 11.0 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Sde2_N_Ubi PF13019.6 KPA46711.1 - 2.3e-70 235.7 0.8 3.4e-70 235.1 0.8 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain His_Phos_1 PF00300.22 KPA46711.1 - 0.043 13.5 1.5 0.065 12.9 1.5 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) LacI PF00356.21 KPA46711.1 - 0.071 12.9 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family VIT1 PF01988.19 KPA46711.1 - 0.51 10.2 1.3 2.2 8.1 1.5 1.9 2 0 0 2 2 2 0 VIT family S10_plectin PF03501.15 KPA46712.1 - 3e-42 142.6 0.1 3.6e-42 142.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain HECT PF00632.25 KPA46714.1 - 7.3e-78 262.1 0.0 1e-77 261.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) L51_S25_CI-B8 PF05047.16 KPA46715.1 - 3e-15 55.8 0.4 5.2e-15 55.1 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MMR_HSR1 PF01926.23 KPA46716.1 - 6.8e-05 22.9 0.0 0.47 10.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase PPI_Ypi1 PF07491.11 KPA46717.1 - 1e-25 89.3 0.9 2.4e-25 88.1 0.9 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor Glu-tRNAGln PF02686.15 KPA46718.1 - 1.3e-12 47.8 0.2 5.8e-12 45.7 0.2 1.9 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.6 KPA46719.1 - 4.6e-114 380.6 19.6 5.2e-114 380.4 19.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KPA46719.1 - 1.3e-11 44.7 15.5 3.2e-06 27.3 0.7 4.3 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPA46719.1 - 2.1e-05 24.3 21.8 0.058 13.5 0.3 7.2 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPA46719.1 - 0.00043 20.3 12.3 0.017 15.3 0.1 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPA46719.1 - 0.0039 17.1 10.8 8.1 6.7 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat PhageMin_Tail PF10145.9 KPA46719.1 - 0.013 15.4 7.2 0.074 12.9 2.0 2.7 2 1 1 3 3 3 0 Phage-related minor tail protein TPR_19 PF14559.6 KPA46719.1 - 0.018 15.5 0.7 0.018 15.5 0.7 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPA46719.1 - 0.019 15.6 18.8 1.5 9.6 0.0 6.3 4 2 2 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 KPA46719.1 - 0.26 11.0 6.3 0.63 9.7 0.4 3.7 1 1 2 4 4 4 0 26S proteasome subunit RPN7 TPR_3 PF07720.12 KPA46719.1 - 0.59 10.2 10.5 0.48 10.5 0.5 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPA46719.1 - 0.84 10.3 23.9 3.1 8.5 2.0 5.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPA46719.1 - 1.2 9.1 15.3 2.6 8.0 0.4 6.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KPA46719.1 - 1.8 8.8 7.7 7.2 6.8 0.3 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 KPA46719.1 - 2.7 8.2 6.5 3.3 7.9 0.0 3.3 2 2 3 5 5 5 0 HemY protein N-terminus TPR_14 PF13428.6 KPA46719.1 - 4 8.5 19.1 22 6.2 0.1 5.6 4 2 2 6 6 5 0 Tetratricopeptide repeat Glyco_hydro_15 PF00723.21 KPA46720.1 - 3.1e-99 332.8 0.7 3.7e-99 332.5 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KPA46720.1 - 5e-34 116.1 1.5 1.6e-33 114.5 1.5 1.9 1 0 0 1 1 1 1 Starch binding domain GAD-like PF08887.11 KPA46720.1 - 0.037 13.8 0.1 0.097 12.5 0.1 1.7 1 0 0 1 1 1 0 GAD-like domain SART-1 PF03343.13 KPA46721.1 - 4.2e-183 610.3 58.9 5e-183 610.1 58.9 1.0 1 0 0 1 1 1 1 SART-1 family GTP_EFTU_D2 PF03144.25 KPA46721.1 - 0.27 11.6 1.3 6.1 7.3 0.1 3.4 3 0 0 3 3 3 0 Elongation factor Tu domain 2 Carbpep_Y_N PF05388.11 KPA46722.1 - 0.015 15.9 0.3 0.017 15.7 0.3 1.2 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide MPS2 PF17060.5 KPA46722.1 - 0.038 13.2 0.3 0.038 13.2 0.3 1.0 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF1192 PF06698.11 KPA46722.1 - 0.047 13.7 0.2 0.075 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) ZirS_C PF16583.5 KPA46722.1 - 0.076 12.6 0.2 0.076 12.6 0.2 1.1 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain MLTD_N PF06474.12 KPA46722.1 - 0.23 11.7 0.5 8.4 6.7 0.0 2.4 2 0 0 2 2 2 0 MltD lipid attachment motif DUF3712 PF12505.8 KPA46723.1 - 1.6e-10 41.3 0.1 3e-08 34.0 0.1 3.3 3 1 0 3 3 3 2 Protein of unknown function (DUF3712) OTCace_N PF02729.21 KPA46724.1 - 8.6e-43 145.9 0.0 1.3e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KPA46724.1 - 3.7e-42 144.0 0.0 5.6e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ALS_ss_C PF10369.9 KPA46725.1 - 3.2e-15 56.1 0.0 3.4e-14 52.8 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KPA46725.1 - 9.7e-14 50.8 0.1 1.7e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KPA46725.1 - 1.3e-08 34.5 0.1 4.3e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 KPA46725.1 - 0.057 13.4 0.0 22 5.1 0.0 3.1 3 1 0 3 3 3 0 ACT domain KH_1 PF00013.29 KPA46726.1 - 8.6e-11 41.5 0.1 4.7e-08 32.8 0.0 2.6 2 1 0 2 2 2 2 KH domain Trp_repressor PF01371.19 KPA46726.1 - 0.16 12.1 0.0 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Trp repressor protein DUF974 PF06159.13 KPA46727.1 - 3.6e-85 285.7 0.0 4.3e-85 285.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.21 KPA46728.1 - 2e-58 197.4 0.0 3.5e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KPA46728.1 - 3.1e-15 55.9 0.8 6.3e-15 54.9 0.8 1.5 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 KPA46728.1 - 1.6e-13 51.2 0.0 3.7e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 uDENN domain C1_2 PF03107.16 KPA46728.1 - 0.024 14.9 4.0 0.047 14.0 4.0 1.5 1 0 0 1 1 1 0 C1 domain C1_1 PF00130.22 KPA46728.1 - 0.035 14.0 5.8 0.071 13.0 5.8 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Leader_CPA1 PF08252.11 KPA46728.1 - 0.059 12.8 1.4 0.12 11.8 1.4 1.5 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide SPA PF08616.10 KPA46728.1 - 0.07 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis Zf_RING PF16744.5 KPA46728.1 - 0.16 12.1 3.1 0.34 11.1 3.1 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-HIT PF04438.16 KPA46728.1 - 0.63 10.0 7.7 1 9.3 7.7 1.4 1 0 0 1 1 1 0 HIT zinc finger PHD PF00628.29 KPA46728.1 - 1.1 9.1 6.5 2.9 7.8 6.5 1.7 1 0 0 1 1 1 0 PHD-finger DUF726 PF05277.12 KPA46729.1 - 1.5e-102 343.1 0.3 2.2e-102 342.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) FoP_duplication PF13865.6 KPA46729.1 - 0.08 13.5 7.8 0.15 12.7 7.8 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 IMS_C PF11799.8 KPA46730.1 - 5.5e-13 49.6 0.0 8.2e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain HHH_5 PF14520.6 KPA46730.1 - 0.029 15.0 0.0 0.74 10.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain Astro_capsid_p PF12226.8 KPA46730.1 - 0.14 11.3 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 KPA46730.1 - 0.32 11.4 6.3 0.61 10.5 6.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain IMS PF00817.20 KPA46731.1 - 1.2e-26 93.5 0.0 1.4e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 impB/mucB/samB family NuiA PF07924.11 KPA46733.1 - 0.025 15.0 0.0 1.5 9.2 0.0 2.3 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein Ribosomal_L3 PF00297.22 KPA46734.1 - 3.8e-183 608.6 9.8 4.3e-183 608.4 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.28 KPA46735.1 - 1.6e-55 182.8 33.1 5.7e-08 32.3 0.1 10.7 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KPA46735.1 - 2.3e-49 161.6 25.1 1.2e-05 25.1 0.0 10.5 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KPA46735.1 - 3.3e-34 114.2 23.0 6.5e-05 22.8 0.0 10.7 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 KPA46735.1 - 6.6e-29 98.2 24.8 0.002 18.4 0.1 10.0 9 1 1 10 10 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 KPA46735.1 - 8.6e-28 96.7 18.8 0.00012 22.5 0.5 7.3 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 KPA46735.1 - 9.7e-28 96.5 13.1 1.6e-06 28.7 0.0 6.8 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KPA46735.1 - 1.5e-27 93.9 11.1 9.2e-05 23.0 0.0 8.7 2 2 7 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 KPA46735.1 - 2e-26 91.4 33.4 1.5e-06 27.7 0.3 9.9 5 3 4 9 9 9 7 TPR repeat TPR_6 PF13174.6 KPA46735.1 - 1.5e-24 84.9 14.7 0.014 15.9 0.7 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 KPA46735.1 - 5e-22 78.0 22.1 2.3e-05 24.6 0.7 7.3 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_9 PF13371.6 KPA46735.1 - 1.8e-18 66.4 7.8 0.00089 19.4 0.1 6.3 2 1 4 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 KPA46735.1 - 2.4e-18 64.7 13.8 0.011 15.7 0.0 9.5 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_15 PF13429.6 KPA46735.1 - 9.7e-13 48.0 11.8 0.0022 17.3 1.4 5.4 1 1 5 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA46735.1 - 1.4e-10 41.2 16.1 2e-08 34.3 2.6 3.9 3 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KPA46735.1 - 2.6e-06 27.3 13.0 0.00027 20.7 1.3 4.8 3 2 2 5 5 5 3 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 KPA46735.1 - 0.00064 20.0 6.7 0.6 10.5 0.3 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KPA46735.1 - 0.0015 18.3 15.4 30 4.7 0.2 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF2225 PF09986.9 KPA46735.1 - 0.0033 17.2 6.3 0.026 14.3 0.3 3.0 2 2 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Fis1_TPR_C PF14853.6 KPA46735.1 - 0.017 15.2 2.4 34 4.6 0.0 4.9 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.6 KPA46735.1 - 0.019 14.4 17.4 1.5 8.2 0.3 5.0 3 1 2 5 5 5 0 Soluble NSF attachment protein, SNAP BTAD PF03704.17 KPA46735.1 - 0.23 11.9 9.5 8.4 6.8 0.6 3.4 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_3 PF07720.12 KPA46735.1 - 6 7.0 23.3 7.4 6.7 0.6 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat SHMT PF00464.19 KPA46736.1 - 3.1e-209 694.5 0.0 3.6e-209 694.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KPA46736.1 - 0.00013 21.3 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPA46736.1 - 0.00036 19.6 0.0 0.00063 18.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KPA46736.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase GNAT_acetyltr_2 PF13718.6 KPA46736.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Cys_Met_Meta_PP PF01053.20 KPA46736.1 - 0.13 10.7 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Bromodomain PF00439.25 KPA46737.1 - 2.7e-19 69.0 0.4 6.5e-19 67.8 0.4 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 KPA46737.1 - 7.9e-10 38.6 0.1 1.6e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Bromodomain associated PSII_Pbs27 PF13326.6 KPA46737.1 - 0.091 13.1 0.5 0.34 11.2 0.4 2.1 1 1 0 1 1 1 0 Photosystem II Pbs27 VanZ PF04892.12 KPA46738.1 - 3.5e-09 37.4 3.5 5.1e-09 36.8 3.5 1.3 1 0 0 1 1 1 1 VanZ like family Saf_2TM PF18303.1 KPA46738.1 - 0.053 13.1 0.3 0.29 10.7 0.0 2.0 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain RseC_MucC PF04246.12 KPA46738.1 - 0.054 13.5 1.2 5.3 7.0 1.1 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC TauE PF01925.19 KPA46738.1 - 0.09 12.4 3.4 1.1 8.8 3.7 1.9 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE PTS_EIIC_2 PF13303.6 KPA46738.1 - 0.12 11.3 1.0 0.16 11.0 1.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF2070 PF09843.9 KPA46738.1 - 0.13 10.5 0.6 0.17 10.1 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YfhO PF09586.10 KPA46738.1 - 0.21 9.8 1.4 0.27 9.4 1.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1097 PF06496.11 KPA46738.1 - 0.3 11.2 3.4 0.42 10.7 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) Prefoldin PF02996.17 KPA46740.1 - 4.1e-35 120.3 0.3 6.6e-35 119.6 0.3 1.3 1 0 0 1 1 1 1 Prefoldin subunit DUF4201 PF13870.6 KPA46740.1 - 0.025 14.3 3.5 0.77 9.5 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) FlaC_arch PF05377.11 KPA46740.1 - 0.03 14.7 1.0 1.2 9.5 0.2 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Filament PF00038.21 KPA46740.1 - 0.053 13.1 4.3 0.69 9.4 4.3 2.0 1 1 0 1 1 1 0 Intermediate filament protein Prefoldin_2 PF01920.20 KPA46740.1 - 0.11 12.4 7.6 0.093 12.7 0.6 2.8 2 1 1 3 3 3 0 Prefoldin subunit Y_phosphatase PF00102.27 KPA46743.1 - 1.4e-45 155.7 0.0 2.1e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KPA46743.1 - 4.8e-05 23.5 0.0 0.00016 21.8 0.0 2.0 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KPA46743.1 - 0.0061 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KPA46743.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RCC1 PF00415.18 KPA46744.1 - 2.1e-29 101.9 6.9 1.5e-08 35.1 0.0 7.9 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KPA46744.1 - 4.2e-15 55.1 17.4 7.8e-10 38.3 0.1 7.3 8 1 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat DNA_gyraseA_C PF03989.13 KPA46744.1 - 0.066 12.7 0.0 8 6.0 0.0 2.8 3 0 0 3 3 3 0 DNA gyrase C-terminal domain, beta-propeller Sec34 PF04136.15 KPA46745.1 - 2.6e-49 166.9 1.2 6e-49 165.8 0.3 2.2 2 0 0 2 2 2 1 Sec34-like family Phasin_2 PF09361.10 KPA46745.1 - 0.046 14.0 0.1 0.17 12.2 0.1 2.0 1 0 0 1 1 1 0 Phasin protein CSN8_PSD8_EIF3K PF10075.9 KPA46745.1 - 0.15 12.1 1.8 17 5.4 0.0 3.4 4 0 0 4 4 4 0 CSN8/PSMD8/EIF3K family Mito_carr PF00153.27 KPA46746.1 - 6.7e-53 176.6 0.7 3e-21 75.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RINT1_TIP1 PF04437.13 KPA46747.1 - 2e-172 574.6 1.0 2.9e-172 574.0 1.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family ADIP PF11559.8 KPA46747.1 - 0.33 11.0 7.1 0.61 10.2 5.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding COG2 PF06148.11 KPA46747.1 - 0.39 10.8 4.4 1.3 9.1 1.5 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4164 PF13747.6 KPA46747.1 - 1.8 8.9 12.6 1 9.7 7.3 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF4164) Fig1 PF12351.8 KPA46748.1 - 1.4e-57 194.7 2.0 1.4e-57 194.7 2.0 2.2 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KPA46748.1 - 8.1e-09 35.4 6.6 1.2e-08 34.9 6.6 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 KPA46748.1 - 0.0094 15.0 9.8 0.017 14.2 9.5 1.7 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF751 PF05421.11 KPA46748.1 - 0.22 12.3 0.2 0.22 12.3 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF751) TFIIB PF00382.19 KPA46750.1 - 7.4e-33 112.4 1.6 1.1e-20 73.4 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KPA46750.1 - 4e-12 45.5 1.2 8.4e-12 44.4 1.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KPA46750.1 - 0.00015 21.8 0.7 0.00047 20.2 0.1 1.9 1 1 1 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 KPA46750.1 - 0.0014 18.7 0.1 1 9.4 0.1 2.5 2 1 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.23 KPA46750.1 - 0.0089 15.8 0.8 0.12 12.1 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sigma70_r4_2 PF08281.12 KPA46750.1 - 0.019 14.7 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 KPA46750.1 - 0.032 13.6 0.0 0.46 9.9 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Rrf2 PF02082.20 KPA46750.1 - 0.056 13.8 0.0 5.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulator zf-ribbon_3 PF13248.6 KPA46750.1 - 0.11 11.9 2.8 0.38 10.2 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain HTH_36 PF13730.6 KPA46750.1 - 0.18 11.8 0.1 16 5.6 0.0 3.2 3 1 0 3 3 3 0 Helix-turn-helix domain Asparaginase PF00710.20 KPA46751.1 - 3.1e-53 180.2 0.7 4.1e-53 179.8 0.7 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KPA46751.1 - 1.3e-18 67.2 0.0 3.9e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain PhoLip_ATPase_C PF16212.5 KPA46752.1 - 1.4e-68 231.4 15.5 1.4e-68 231.4 15.5 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KPA46752.1 - 7.4e-25 86.4 1.8 3.6e-23 81.0 0.0 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KPA46752.1 - 1.2e-11 44.5 0.0 1.5e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPA46752.1 - 1.8e-11 44.7 0.8 7e-07 29.7 0.0 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KPA46752.1 - 1.2e-10 41.2 0.0 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KPA46752.1 - 0.014 15.2 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KPA46752.1 - 0.093 12.9 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Nif11 PF07862.11 KPA46752.1 - 0.28 11.5 1.2 4.6 7.6 0.3 2.7 2 0 0 2 2 2 0 Nif11 domain Sacchrp_dh_NADP PF03435.18 KPA46753.1 - 7.9e-07 29.4 0.0 1.4e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KPA46753.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ZnuA PF01297.17 KPA46753.1 - 0.18 11.2 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic MFS_1 PF07690.16 KPA46754.1 - 1.7e-40 139.0 54.4 3.9e-39 134.6 51.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4191 PF13829.6 KPA46754.1 - 4.8 6.5 6.8 14 4.9 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) CUE PF02845.16 KPA46755.1 - 2.3e-07 30.4 0.0 3.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain TAXi_N PF14543.6 KPA46756.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Ofd1_CTDD PF10637.9 KPA46757.1 - 5.1e-93 311.1 0.0 1.5e-88 296.5 0.2 2.4 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KPA46757.1 - 1.5e-25 89.6 0.0 9.6e-25 87.1 0.0 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KPA46757.1 - 4.2e-12 46.8 0.0 8.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1963 PF09234.10 KPA46757.1 - 0.025 15.1 0.1 0.063 13.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) Ribul_P_3_epim PF00834.19 KPA46758.1 - 2.1e-61 206.8 0.0 1e-60 204.6 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 KPA46758.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.14 KPA46758.1 - 0.018 14.4 0.2 0.028 13.7 0.2 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG QRPTase_C PF01729.19 KPA46758.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain PG_binding_3 PF09374.10 KPA46758.1 - 0.15 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain CFEM PF05730.11 KPA46759.1 - 3.1e-15 56.0 11.9 5.9e-15 55.1 11.9 1.5 1 0 0 1 1 1 1 CFEM domain Herpes_capsid PF06112.11 KPA46759.1 - 2.3 8.3 10.2 3.8 7.6 10.2 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Abhydrolase_6 PF12697.7 KPA46760.1 - 5.3e-23 82.8 0.4 9.3e-23 82.0 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPA46760.1 - 1.6e-08 34.5 0.1 5.6e-08 32.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPA46760.1 - 6.6e-07 28.8 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KPA46760.1 - 0.00016 21.8 0.1 0.0004 20.6 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain DUF676 PF05057.14 KPA46760.1 - 0.038 13.5 0.0 0.079 12.5 0.0 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KPA46760.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 KPA46760.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.18 KPA46761.1 - 3.7e-07 30.1 7.6 6.2e-07 29.4 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF202 PF02656.15 KPA46762.1 - 0.00012 22.4 1.4 0.00012 22.4 1.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) zf-C2H2 PF00096.26 KPA46763.1 - 9.7e-05 22.6 22.9 0.00076 19.8 0.6 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPA46763.1 - 0.0026 18.5 0.6 0.0026 18.5 0.6 4.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KPA46763.1 - 0.019 15.0 0.2 0.057 13.4 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KPA46763.1 - 0.03 14.2 0.2 0.96 9.4 0.2 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type YpsA PF06908.11 KPA46763.1 - 0.59 10.1 6.1 1.2 9.1 6.1 1.4 1 0 0 1 1 1 0 YspA SLOG family TRP PF06011.12 KPA46764.1 - 2.9e-138 461.2 14.5 3.5e-138 460.9 14.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KPA46764.1 - 3e-35 121.6 0.2 5.2e-35 120.8 0.2 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 KPA46764.1 - 0.006 17.0 0.4 0.011 16.2 0.4 1.4 1 0 0 1 1 1 1 ML domain FtsL PF04999.13 KPA46764.1 - 0.12 12.4 5.1 0.2 11.7 0.0 2.5 2 0 0 2 2 2 0 Cell division protein FtsL PDR_CDR PF06422.12 KPA46764.1 - 0.98 9.4 3.2 0.75 9.7 0.2 2.3 2 0 0 2 2 2 0 CDR ABC transporter RNA_ligase PF09414.10 KPA46765.1 - 1.2e-28 100.5 0.0 1.6e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 RNA ligase VPS9 PF02204.18 KPA46766.1 - 4.9e-31 107.0 0.1 8.1e-31 106.3 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KPA46766.1 - 2.1e-15 56.8 0.0 4.5e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KPA46766.1 - 3.4e-08 33.0 0.0 8.6e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 CUE domain ABC_trans_N PF14510.6 KPA46766.1 - 0.18 12.5 0.6 1.2 9.8 0.0 2.8 2 0 0 2 2 2 0 ABC-transporter N-terminal DUF4291 PF14124.6 KPA46767.1 - 1.2e-69 233.8 0.1 1.4e-69 233.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) DUF3378 PF11858.8 KPA46767.1 - 0.068 13.3 1.3 0.34 11.1 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) HET PF06985.11 KPA46768.1 - 1.6e-14 54.5 2.9 3.4e-11 43.7 0.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 KPA46769.1 - 7e-57 192.7 0.0 9.3e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPA46769.1 - 9.5e-45 152.5 0.0 1.2e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPA46769.1 - 6.3e-10 39.3 0.0 8.5e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KPA46769.1 - 0.0093 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KPA46769.1 - 0.02 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sod_Cu PF00080.20 KPA46771.1 - 5.9e-09 36.2 0.1 8.6e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Aminotran_5 PF00266.19 KPA46772.1 - 3.7e-08 32.7 0.0 0.026 13.5 0.0 3.5 2 1 0 2 2 2 2 Aminotransferase class-V LPP20 PF02169.16 KPA46772.1 - 0.76 10.2 5.9 1.8 8.9 2.2 2.5 2 0 0 2 2 2 0 LPP20 lipoprotein DUF4702 PF15774.5 KPA46772.1 - 0.83 8.5 7.2 0.43 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4702) Fungal_trans PF04082.18 KPA46773.1 - 2.3e-15 56.4 0.0 3.7e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA46773.1 - 1.9e-06 27.9 13.4 3e-06 27.2 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPA46774.1 - 1.7e-18 66.6 0.9 2.3e-18 66.2 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA46774.1 - 3e-07 30.5 9.0 4.7e-07 29.8 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 KPA46774.1 - 0.014 15.3 0.4 0.035 14.1 0.4 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Sugar_tr PF00083.24 KPA46775.1 - 1e-106 357.6 23.9 1.2e-106 357.4 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPA46775.1 - 1.9e-30 106.0 32.3 4.3e-25 88.4 5.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPA46775.1 - 3.5e-05 22.5 24.7 0.00018 20.2 4.9 3.6 2 2 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 KPA46775.1 - 8.6 4.5 18.9 0.13 10.5 1.5 3.4 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_7 PF00840.20 KPA46776.1 - 1.8e-197 656.3 19.0 2.3e-197 656.0 19.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KPA46776.1 - 1.2e-12 47.6 6.9 1.2e-12 47.6 6.9 4.3 4 1 0 4 4 4 1 Fungal cellulose binding domain SNF5 PF04855.12 KPA46777.1 - 3.7e-92 308.4 0.0 4.8e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KPA46777.1 - 0.0022 17.6 1.8 0.0052 16.4 1.8 1.7 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 KPA46777.1 - 0.03 14.0 4.9 0.13 12.0 1.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Terminase_GpA PF05876.12 KPA46777.1 - 0.14 10.7 0.4 0.25 9.9 0.4 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zinc_ribbon_10 PF10058.9 KPA46777.1 - 0.34 10.7 1.4 0.59 9.9 0.0 2.0 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein CAP PF00188.26 KPA46778.1 - 7.8e-14 52.6 1.8 9.9e-14 52.3 1.8 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAN_3 PF08277.12 KPA46778.1 - 0.14 12.0 1.8 0.28 11.0 1.8 1.4 1 0 0 1 1 1 0 PAN-like domain DRIM PF07539.12 KPA46779.1 - 4.3e-203 676.1 0.4 2.2e-202 673.7 0.0 2.5 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.22 KPA46779.1 - 0.001 19.1 3.6 2.9 8.4 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat DUF2828 PF11443.8 KPA46779.1 - 0.15 10.1 3.5 0.34 9.0 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Sec7_N PF12783.7 KPA46779.1 - 0.2 11.5 1.9 8.5 6.3 0.1 4.4 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3361 PF11841.8 KPA46779.1 - 0.27 11.2 3.1 19 5.2 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3361) CwfJ_C_1 PF04677.15 KPA46780.1 - 1e-22 80.3 0.0 2.3e-22 79.1 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KPA46780.1 - 3.7e-18 66.2 0.4 7e-18 65.3 0.4 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Rhodanese PF00581.20 KPA46781.1 - 6.7e-13 49.1 0.0 1.4e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DNA_pol_phi PF04931.13 KPA46782.1 - 3.3e-208 693.5 25.8 4.3e-208 693.1 25.8 1.1 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 KPA46782.1 - 0.00021 20.8 25.2 0.00021 20.8 25.2 2.2 2 0 0 2 2 2 1 SDA1 DUF883 PF05957.13 KPA46782.1 - 0.38 11.4 0.1 0.38 11.4 0.1 3.6 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF1676 PF07898.13 KPA46782.1 - 1.7 8.7 7.8 2.2 8.3 6.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) Anti-adapt_IraP PF10796.9 KPA46782.1 - 1.9 9.1 4.6 21 5.8 0.2 4.3 4 0 0 4 4 4 0 Sigma-S stabilisation anti-adaptor protein Proteasome PF00227.26 KPA46783.1 - 1.5e-45 155.0 0.0 1.3e-29 103.1 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KPA46783.1 - 6.6e-11 41.7 0.7 9.3e-11 41.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2457 PF10446.9 KPA46783.1 - 0.71 8.9 14.4 0.84 8.7 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 KPA46783.1 - 3.3 6.9 11.5 4.2 6.6 11.5 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KPA46783.1 - 8.7 6.8 15.3 17 5.9 15.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4390 PF14334.6 KPA46784.1 - 0.053 12.9 0.2 0.087 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) LRR_6 PF13516.6 KPA46785.1 - 1.6e-09 37.0 2.7 0.16 12.1 0.0 6.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KPA46785.1 - 1.2e-05 25.6 6.0 5.7 7.5 0.0 5.5 6 1 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KPA46785.1 - 0.00029 21.0 0.1 51 5.0 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 KPA46785.1 - 0.0092 15.7 9.2 3.1 7.6 0.0 5.0 4 1 0 4 4 4 2 Leucine rich repeat CDC45 PF02724.14 KPA46785.1 - 6.9 4.8 11.6 2 6.6 8.7 1.5 2 0 0 2 2 2 0 CDC45-like protein Cytochrom_C1 PF02167.15 KPA46786.1 - 3.6e-91 304.8 0.0 4.7e-91 304.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KPA46786.1 - 0.0076 16.6 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III IBR PF01485.21 KPA46787.1 - 0.028 14.6 5.5 0.047 13.9 5.5 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Tsc35 PF15079.6 KPA46787.1 - 0.12 11.9 0.2 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 Testis-specific protein 35 AAA PF00004.29 KPA46788.1 - 1.2e-40 139.0 0.0 2.2e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPA46788.1 - 5.9e-07 29.2 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KPA46788.1 - 6.8e-05 22.9 0.1 0.00043 20.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPA46788.1 - 0.0001 22.6 0.0 0.0069 16.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KPA46788.1 - 0.00023 21.3 0.0 0.00084 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KPA46788.1 - 0.0007 20.0 0.1 0.014 15.8 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KPA46788.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KPA46788.1 - 0.0079 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KPA46788.1 - 0.029 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KPA46788.1 - 0.035 13.6 0.0 0.097 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KPA46788.1 - 0.042 14.2 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KPA46788.1 - 0.051 13.7 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPA46788.1 - 0.051 14.1 0.0 0.5 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPA46788.1 - 0.052 13.3 0.1 0.28 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KPA46788.1 - 0.059 13.2 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KPA46788.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KPA46788.1 - 0.17 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.24 KPA46789.1 - 2.3e-147 491.6 13.8 2.6e-147 491.4 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HECT PF00632.25 KPA46789.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) T2SSF PF00482.23 KPA46790.1 - 0.011 15.7 0.9 0.02 14.9 0.9 1.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F GrpE PF01025.19 KPA46790.1 - 0.012 15.3 2.4 0.015 15.0 2.4 1.1 1 0 0 1 1 1 0 GrpE Seryl_tRNA_N PF02403.22 KPA46790.1 - 0.04 14.1 6.3 0.1 12.9 1.1 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.11 KPA46790.1 - 0.17 12.2 4.5 1.7 8.9 1.8 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Urease_linker PF18473.1 KPA46790.1 - 0.28 11.1 1.6 0.35 10.8 0.1 2.0 2 0 0 2 2 2 0 Urease subunit beta-alpha linker domain Noelin-1 PF12308.8 KPA46790.1 - 1 9.4 8.3 2 8.4 1.5 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein COX17 PF05051.13 KPA46791.1 - 2.4e-21 75.8 7.3 2.9e-21 75.6 7.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Abhydrolase_3 PF07859.13 KPA46792.1 - 9.8e-38 130.1 0.0 1.3e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KPA46792.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family HSP20 PF00011.21 KPA46793.1 - 8.9e-11 41.9 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KPA46793.1 - 0.00027 20.4 0.0 0.0021 17.6 0.0 2.3 1 1 0 1 1 1 1 HSP20-like domain found in ArsA LEAP-2 PF07359.11 KPA46793.1 - 0.25 11.2 0.0 0.43 10.5 0.0 1.3 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) GRP PF07172.11 KPA46793.1 - 0.32 11.7 6.3 0.72 10.6 6.3 1.6 1 0 0 1 1 1 0 Glycine rich protein family CH PF00307.31 KPA46794.1 - 0.0011 19.1 0.1 0.029 14.6 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain PRCC PF10253.9 KPA46795.1 - 0.011 16.5 2.8 0.011 16.5 2.8 1.5 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF5349 PF17298.2 KPA46795.1 - 0.081 12.7 12.5 0.11 12.2 12.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) KAR9 PF08580.10 KPA46796.1 - 3.9e-178 594.2 3.4 3.9e-178 594.2 3.4 1.6 1 1 0 1 1 1 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.11 KPA46796.1 - 0.025 15.1 12.7 0.43 11.2 1.5 4.6 2 2 2 4 4 4 0 Syntaxin 6, N-terminal EAP30 PF04157.16 KPA46796.1 - 0.12 11.7 3.8 6.3 6.0 0.3 2.9 2 1 1 3 3 3 0 EAP30/Vps36 family DALR_1 PF05746.15 KPA46796.1 - 0.15 12.3 0.4 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 DALR anticodon binding domain DUF4795 PF16043.5 KPA46796.1 - 0.57 9.7 9.5 0.59 9.7 2.4 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) FliT PF05400.13 KPA46796.1 - 2.9 8.8 7.0 6.3 7.7 0.5 3.6 3 0 0 3 3 3 0 Flagellar protein FliT PLU-1 PF08429.11 KPA46796.1 - 3.9 6.6 7.5 2.2 7.3 0.3 3.2 2 2 0 2 2 2 0 PLU-1-like protein Spectrin PF00435.21 KPA46796.1 - 4.5 7.8 11.7 1.6 9.3 1.6 3.8 3 1 0 3 3 3 0 Spectrin repeat DEAD PF00270.29 KPA46797.1 - 1.4e-22 80.3 0.0 3.4e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA46797.1 - 3.7e-18 65.9 0.0 2.2e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KPA46797.1 - 2e-16 60.5 3.9 5.5e-16 59.1 3.9 1.9 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 KPA46797.1 - 2.4e-13 49.8 0.0 5.8e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 KPA46797.1 - 1.9e-06 28.0 0.0 4.5e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.23 KPA46797.1 - 5.3e-05 23.1 0.4 0.00026 20.9 0.1 2.4 2 0 0 2 2 2 1 HRDC domain PCRF PF03462.18 KPA46797.1 - 0.88 9.4 3.2 36 4.1 5.1 2.5 2 0 0 2 2 2 0 PCRF domain DUF4200 PF13863.6 KPA46797.1 - 1.4 9.3 7.4 4.6 7.7 7.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.22 KPA46797.1 - 1.7 8.9 9.4 31 4.9 9.3 2.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Ank_2 PF12796.7 KPA46798.1 - 2.2e-43 146.7 6.6 6.5e-13 49.1 0.0 9.5 6 2 2 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPA46798.1 - 6.2e-35 119.1 0.1 0.00021 21.8 0.0 11.1 9 2 3 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPA46798.1 - 1.3e-34 114.3 2.5 0.0021 18.4 0.0 12.4 13 0 0 13 13 13 6 Ankyrin repeat Ank PF00023.30 KPA46798.1 - 2.2e-26 91.1 6.5 0.00055 20.3 0.0 10.6 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 KPA46798.1 - 8.7e-25 86.5 3.3 0.0003 21.0 0.1 9.9 10 2 1 11 11 11 6 Ankyrin repeats (many copies) Imm49 PF15575.6 KPA46798.1 - 0.0016 18.3 0.1 0.41 10.4 0.0 2.7 1 1 1 2 2 2 2 Immunity protein 49 DUF1772 PF08592.11 KPA46799.1 - 7.1e-08 32.9 2.2 1e-07 32.3 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Helicase_C PF00271.31 KPA46800.1 - 5.9e-21 74.9 0.1 1.6e-20 73.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA46800.1 - 1.2e-20 74.2 0.0 2.3e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPA46800.1 - 1.9e-15 57.1 0.0 5.7e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KPA46800.1 - 0.00036 20.3 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KPA46800.1 - 0.02 15.2 0.0 0.17 12.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain PGA2 PF07543.12 KPA46800.1 - 0.62 10.0 10.3 1.4 8.9 10.3 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 TAP_C PF03943.13 KPA46801.1 - 6.1e-18 64.2 2.0 1e-17 63.5 1.3 1.8 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.7 KPA46801.1 - 3.5e-09 36.8 0.1 9.4e-05 22.7 0.0 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) NTF2 PF02136.20 KPA46801.1 - 0.00018 22.1 0.0 0.00047 20.7 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_6 PF13516.6 KPA46801.1 - 0.0039 17.1 0.1 3.8 7.8 0.0 3.0 3 0 0 3 3 3 2 Leucine Rich repeat RRM_9 PF18444.1 KPA46801.1 - 0.0043 16.9 0.0 0.019 14.8 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif LRR_8 PF13855.6 KPA46801.1 - 0.15 11.8 0.3 1.3 8.8 0.0 2.7 2 1 0 2 2 2 0 Leucine rich repeat Kelch_6 PF13964.6 KPA46802.1 - 3.5e-05 23.9 2.9 2.4 8.6 0.0 5.7 6 0 0 6 6 6 1 Kelch motif Kelch_3 PF13415.6 KPA46802.1 - 0.00013 22.2 0.0 6.3 7.2 0.0 5.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Rax2 PF12768.7 KPA46802.1 - 0.0015 18.0 1.9 0.003 17.1 1.4 1.7 1 1 0 1 1 1 1 Cortical protein marker for cell polarity Amnionless PF14828.6 KPA46802.1 - 0.0036 16.2 0.3 0.0062 15.4 0.3 1.3 1 0 0 1 1 1 1 Amnionless RIFIN PF02009.16 KPA46802.1 - 0.059 13.3 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Rifin AJAP1_PANP_C PF15298.6 KPA46802.1 - 0.13 12.5 5.6 0.24 11.6 5.6 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus TMEM154 PF15102.6 KPA46802.1 - 0.16 11.8 11.7 11 5.9 11.7 2.4 1 1 0 1 1 1 0 TMEM154 protein family Kelch_5 PF13854.6 KPA46802.1 - 0.26 11.3 3.6 3.7 7.6 0.0 4.0 4 0 0 4 4 4 0 Kelch motif SBBP PF06739.11 KPA46802.1 - 0.6 10.2 0.0 0.6 10.2 0.0 2.5 3 0 0 3 3 3 0 Beta-propeller repeat Gram_pos_anchor PF00746.21 KPA46802.1 - 0.92 9.5 4.6 2.6 8.1 4.6 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif HLH PF00010.26 KPA46803.1 - 1.9e-10 40.5 0.0 3.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 KPA46803.1 - 0.0081 16.2 1.3 0.022 14.8 1.3 1.7 1 0 0 1 1 1 1 bZIP transcription factor Cnn_1N PF07989.11 KPA46803.1 - 0.012 15.7 1.3 0.012 15.7 1.3 2.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Myc-LZ PF02344.15 KPA46803.1 - 0.065 13.3 0.8 0.12 12.5 0.8 1.4 1 0 0 1 1 1 0 Myc leucine zipper domain HALZ PF02183.18 KPA46803.1 - 0.13 12.5 3.2 0.26 11.6 3.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper FlxA PF14282.6 KPA46803.1 - 1.5 8.8 15.3 0.44 10.6 8.0 2.8 2 0 0 2 2 2 0 FlxA-like protein Pcc1 PF09341.10 KPA46804.1 - 5.2e-31 106.6 0.3 6.5e-31 106.3 0.3 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.6 KPA46805.1 - 1.5e-42 145.4 0.0 2.7e-40 138.1 0.0 2.7 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KPA46805.1 - 9.4e-17 61.1 0.0 2.2e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KPA46805.1 - 5.4e-06 26.1 0.0 9.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KPA46805.1 - 0.091 12.9 0.4 0.26 11.4 0.0 1.9 3 0 0 3 3 3 0 Inositol hexakisphosphate HeLo PF14479.6 KPA46806.1 - 1.5e-51 175.2 0.6 6.6e-51 173.1 0.2 1.9 2 0 0 2 2 2 1 Prion-inhibition and propagation TetR_C_31 PF17940.1 KPA46806.1 - 0.049 13.8 3.1 0.12 12.6 0.1 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain APAF1_C PF17908.1 KPA46806.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 APAF-1 helical domain ABC_membrane PF00664.23 KPA46807.1 - 7.7e-83 278.3 26.3 9.7e-44 150.0 1.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPA46807.1 - 1.3e-66 223.3 0.0 6.1e-32 111.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPA46807.1 - 1.1e-14 54.4 1.4 0.00027 20.4 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KPA46807.1 - 5.7e-08 33.3 2.7 0.0066 16.9 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KPA46807.1 - 1.4e-07 31.1 0.2 0.022 14.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KPA46807.1 - 3.2e-07 30.3 0.5 0.0033 17.2 0.0 3.5 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 KPA46807.1 - 4.7e-07 29.3 0.0 0.026 13.8 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.6 KPA46807.1 - 9.8e-07 29.1 0.4 0.19 12.0 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KPA46807.1 - 4.6e-06 26.7 1.2 0.58 9.9 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KPA46807.1 - 7.1e-06 26.0 0.0 0.017 15.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KPA46807.1 - 1.4e-05 25.7 2.9 0.21 12.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 KPA46807.1 - 2.2e-05 23.4 0.2 0.0065 15.3 0.0 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DUF3987 PF13148.6 KPA46807.1 - 0.00016 20.8 0.0 0.52 9.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) DUF87 PF01935.17 KPA46807.1 - 0.00027 21.1 0.1 0.9 9.6 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain APS_kinase PF01583.20 KPA46807.1 - 0.00032 20.6 0.1 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase G-alpha PF00503.20 KPA46807.1 - 0.00036 19.8 0.0 0.31 10.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.6 KPA46807.1 - 0.00062 19.9 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KPA46807.1 - 0.001 19.6 0.1 1.7 9.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KPA46807.1 - 0.0022 17.6 0.3 1.6 8.2 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 KPA46807.1 - 0.0027 18.1 0.1 27 5.2 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KPA46807.1 - 0.0029 17.8 0.5 3.8 7.8 0.1 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KPA46807.1 - 0.004 17.2 0.1 11 6.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KPA46807.1 - 0.0045 16.2 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain MMR_HSR1 PF01926.23 KPA46807.1 - 0.009 16.1 0.0 2.6 8.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.6 KPA46807.1 - 0.018 15.5 0.0 12 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KPA46807.1 - 0.029 14.1 1.7 1.8 8.2 0.0 2.4 3 0 0 3 3 2 0 AAA ATPase domain AAA_24 PF13479.6 KPA46807.1 - 0.058 13.1 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KPA46807.1 - 0.092 12.4 0.0 16 5.1 0.0 3.1 3 0 0 3 3 2 0 Thymidylate kinase PRK PF00485.18 KPA46807.1 - 0.13 12.0 0.1 9.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KPA46807.1 - 0.17 12.3 0.0 10 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Cytochrome-c551 PF10643.9 KPA46807.1 - 1.8 8.1 5.0 1.2 8.6 2.7 1.9 2 0 0 2 2 1 0 Photosystem P840 reaction-centre cytochrome c-551 Acetyltransf_3 PF13302.7 KPA46808.1 - 3.1e-24 86.2 0.0 1.2e-23 84.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPA46808.1 - 5.6e-06 26.6 0.0 7.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KPA46808.1 - 0.0045 16.7 0.0 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KPA46809.1 - 1.8e-11 43.6 73.5 3.1e-06 26.3 39.1 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KPA46809.1 - 0.45 8.9 27.4 0.44 8.9 25.8 1.7 1 1 1 2 2 2 0 Fungal trichothecene efflux pump (TRI12) SURF4 PF02077.15 KPA46810.1 - 1.9e-96 322.8 6.1 2.2e-96 322.6 6.1 1.0 1 0 0 1 1 1 1 SURF4 family DUF1129 PF06570.11 KPA46810.1 - 1.3 8.5 5.6 1.3 8.5 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) HhH-GPD PF00730.25 KPA46811.1 - 0.038 14.4 0.0 0.074 13.5 0.0 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DUF3439 PF11921.8 KPA46811.1 - 0.083 12.9 0.2 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RRM_1 PF00076.22 KPA46812.1 - 6e-19 67.6 0.3 1.2e-18 66.7 0.3 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPA46812.1 - 2.6e-05 23.8 0.0 3.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPA46812.1 - 0.034 14.0 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif SWIM PF04434.17 KPA46813.1 - 0.00027 20.5 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 SWIM zinc finger DUF515 PF04415.12 KPA46813.1 - 0.18 10.2 4.0 0.29 9.5 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) AF-4 PF05110.13 KPA46813.1 - 6.7 4.7 16.9 9.4 4.2 16.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pkinase_Tyr PF07714.17 KPA46814.1 - 0.0038 16.6 0.1 0.02 14.2 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 KPA46814.1 - 0.0058 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.18 KPA46815.1 - 0.011 15.9 6.7 0.011 15.9 6.7 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 KPA46816.1 - 4.1e-12 46.5 0.0 5.5e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family IBN_N PF03810.19 KPA46817.1 - 3.6e-14 52.4 3.8 1.7e-12 47.1 0.0 4.0 3 1 1 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 KPA46817.1 - 1.8e-08 33.6 0.1 5.5e-08 32.0 0.1 1.8 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 KPA46817.1 - 0.00017 21.7 2.7 0.0013 18.8 0.1 3.7 4 0 0 4 4 4 1 Exportin 1-like protein RIX1 PF08167.12 KPA46817.1 - 0.0027 17.5 0.1 0.8 9.4 0.0 3.8 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 KPA46817.1 - 0.0048 17.3 2.9 0.89 10.0 0.4 3.8 4 0 0 4 4 4 1 HEAT repeats GRIP PF01465.20 KPA46817.1 - 0.027 14.4 0.3 0.72 9.8 0.1 3.2 2 1 1 3 3 3 0 GRIP domain Vac14_Fab1_bd PF12755.7 KPA46817.1 - 0.04 14.5 3.5 4.7 7.9 0.0 4.0 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KPA46817.1 - 0.11 12.8 1.0 1.4 9.3 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat Cnd1 PF12717.7 KPA46817.1 - 0.42 10.6 4.9 0.41 10.7 0.1 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 SIMPL PF04402.14 KPA46817.1 - 0.89 10.0 8.3 0.39 11.2 5.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF541) Caleosin PF05042.13 KPA46818.1 - 6.8e-68 227.9 0.2 8.2e-68 227.6 0.2 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 KPA46818.1 - 0.00083 19.1 7.8 0.014 15.3 0.2 4.4 5 0 0 5 5 5 1 EF-hand domain EF-hand_7 PF13499.6 KPA46818.1 - 0.0033 17.9 0.7 0.14 12.6 0.1 2.9 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KPA46818.1 - 0.11 12.1 8.4 0.19 11.4 0.2 4.2 5 0 0 5 5 5 0 EF hand EF-hand_8 PF13833.6 KPA46818.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.6 4 0 0 4 4 4 0 EF-hand domain pair ISN1 PF06437.11 KPA46820.1 - 2.7e-199 662.2 0.0 3.1e-199 662.0 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Cys_Met_Meta_PP PF01053.20 KPA46821.1 - 4.7e-32 111.0 0.0 6.1e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta-Casp PF10996.8 KPA46821.1 - 0.087 13.1 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Beta-Casp domain Peptidase_M48 PF01435.18 KPA46821.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 CBAH PF02275.18 KPA46822.1 - 1.6e-08 34.6 0.0 1.7e-07 31.2 0.0 2.2 1 1 1 2 2 2 1 Linear amide C-N hydrolases, choloylglycine hydrolase family GH131_N PF18271.1 KPA46823.1 - 8.3e-84 281.3 0.1 9.5e-84 281.1 0.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 KPA46823.1 - 0.038 13.8 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Pkinase PF00069.25 KPA46824.1 - 5.1e-49 167.0 0.0 7e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46824.1 - 3.8e-24 85.4 0.3 2e-22 79.8 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KPA46824.1 - 0.0088 15.4 0.1 0.13 11.6 0.0 2.6 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KPA46824.1 - 0.014 14.2 0.0 0.036 12.9 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase MMM1 PF10296.9 KPA46825.1 - 2.7e-08 33.3 0.3 2.1e-06 27.0 0.1 2.9 2 1 0 3 3 3 2 Maintenance of mitochondrial morphology protein 1 Mcp5_PH PF12814.7 KPA46826.1 - 2.1e-46 157.0 0.1 4.4e-46 156.0 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KPA46826.1 - 1.5e-05 25.4 0.0 4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 PH domain SKG6 PF08693.10 KPA46827.1 - 0.0071 15.7 1.2 0.016 14.6 1.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 KPA46827.1 - 0.087 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF5337 PF17272.2 KPA46827.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Syndecan PF01034.20 KPA46827.1 - 0.22 11.4 0.8 0.58 10.1 0.1 1.9 2 0 0 2 2 2 0 Syndecan domain Gly_transf_sug PF04488.15 KPA46828.1 - 2.4e-09 37.7 0.0 5e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KPA46828.1 - 5.9e-06 25.9 0.1 7.8e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein zf-CCCH PF00642.24 KPA46829.1 - 2.2e-07 30.6 2.6 3.4e-07 30.0 2.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KPA46829.1 - 0.00016 21.6 4.4 0.00016 21.6 4.4 2.1 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 KPA46829.1 - 0.0015 18.3 2.7 0.0024 17.6 2.7 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KPA46829.1 - 0.047 14.2 2.9 0.091 13.3 2.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_8 PF18633.1 KPA46829.1 - 0.16 12.1 1.2 0.43 10.7 1.2 1.7 1 0 0 1 1 1 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 Autophagy_N PF03986.13 KPA46830.1 - 2e-46 157.3 0.6 3.7e-46 156.5 0.0 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KPA46830.1 - 1.7e-16 60.5 0.1 3.7e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KPA46830.1 - 5.4e-16 57.8 0.6 9.8e-16 57.0 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal TSC22 PF01166.18 KPA46831.1 - 0.0055 17.0 0.4 0.014 15.7 0.4 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family TPR_MLP1_2 PF07926.12 KPA46831.1 - 0.0077 16.3 9.8 0.021 14.9 9.7 1.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 KPA46831.1 - 0.75 10.7 8.0 1.8 9.5 8.0 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 KPA46831.1 - 0.95 9.5 4.1 1.6 8.8 4.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mod_r PF07200.13 KPA46831.1 - 1 9.4 5.8 2 8.5 5.5 1.6 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CCDC-167 PF15188.6 KPA46831.1 - 1.1 9.6 4.6 2.4 8.6 4.6 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2458 PF10454.9 KPA46831.1 - 2 8.1 6.6 3.4 7.3 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DNA_pol_B PF00136.21 KPA46832.1 - 3.3e-104 349.2 0.0 4.3e-104 348.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KPA46832.1 - 1.5e-22 80.3 0.0 3.2e-14 52.8 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KPA46832.1 - 1.9e-15 57.1 3.7 1.9e-15 57.1 3.7 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Cript PF10235.9 KPA46832.1 - 0.13 12.8 1.0 0.41 11.2 1.0 1.8 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-C3HC4_3 PF13920.6 KPA46832.1 - 0.14 12.0 1.3 0.37 10.7 1.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KPA46832.1 - 8.3 6.4 6.3 1.3 9.0 0.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Slu7 PF11708.8 KPA46833.1 - 4.3e-75 252.9 21.7 4.3e-75 252.9 21.7 3.3 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KPA46833.1 - 0.071 12.8 0.6 0.13 12.1 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KPA46833.1 - 0.26 11.4 3.2 0.5 10.5 3.2 1.4 1 0 0 1 1 1 0 Zinc knuckle S4 PF01479.25 KPA46834.1 - 4.7e-12 45.4 0.6 4.7e-12 45.4 0.6 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KPA46834.1 - 1.6e-06 28.9 0.0 2.8e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 KPA46835.1 - 8.3e-47 157.2 5.5 8.3e-47 157.2 5.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e DUF5486 PF17588.2 KPA46835.1 - 0.067 13.1 2.7 0.46 10.4 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5486) ANTH PF07651.16 KPA46836.1 - 7e-82 274.5 0.0 7e-82 274.5 0.0 3.2 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.17 KPA46836.1 - 1.8e-55 187.4 9.4 1.8e-55 187.4 9.4 6.0 4 1 3 7 7 7 2 I/LWEQ domain ENTH PF01417.20 KPA46836.1 - 0.0046 17.0 0.2 0.23 11.5 0.0 3.2 2 1 0 2 2 2 1 ENTH domain MATalpha_HMGbox PF04769.12 KPA46837.1 - 2.7e-70 235.8 0.0 3.8e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box MAT1-1-2 PF17043.5 KPA46838.1 - 3.6e-45 153.6 0.0 5e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Mating type protein 1-1-2 of unknown function DUF507 PF04368.13 KPA46838.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF507) HMG_box PF00505.19 KPA46839.1 - 6.8e-16 58.4 0.2 1.3e-15 57.6 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Exo_endo_phos PF03372.23 KPA46840.1 - 2.4e-11 43.6 0.1 3.8e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family COX6A PF02046.15 KPA46841.1 - 5.5e-51 171.8 3.8 6.5e-51 171.5 3.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2933 PF11666.8 KPA46841.1 - 0.055 13.5 0.2 0.096 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) DUF1770 PF08589.10 KPA46843.1 - 4.4e-37 127.0 1.0 5.6e-37 126.7 1.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.6 KPA46844.1 - 1.6e-05 24.3 0.0 3.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DNA_pol_phi PF04931.13 KPA46844.1 - 7 4.6 20.2 10 4.1 20.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_L2_C PF03947.18 KPA46845.1 - 1.5e-41 141.5 4.7 2.6e-41 140.7 4.7 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KPA46845.1 - 1.4e-12 47.4 0.1 3.1e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.24 KPA46846.1 - 2e-67 227.7 0.0 2.3e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KPA46846.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 KPA46847.1 - 1.3e-53 182.3 2.5 5.7e-53 180.2 0.3 2.1 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KPA46847.1 - 1.7e-18 67.5 1.4 6.5e-18 65.7 0.1 2.7 3 0 0 3 3 3 1 Telomerase activating protein Est1 PHB_depo_C PF06850.11 KPA46847.1 - 0.033 13.6 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 PHB de-polymerase C-terminus PDE4_UCR PF18100.1 KPA46847.1 - 0.13 12.9 0.6 0.47 11.1 0.0 2.3 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) zf-C2H2 PF00096.26 KPA46848.1 - 0.019 15.4 0.7 0.019 15.4 0.7 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type G10 PF01125.17 KPA46849.1 - 5.3e-63 211.1 4.1 6e-63 211.0 4.1 1.0 1 0 0 1 1 1 1 G10 protein Complex1_LYR_2 PF13233.6 KPA46850.1 - 1.3e-06 29.1 0.2 1.8e-06 28.6 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KPA46850.1 - 0.00049 20.1 0.2 0.001 19.0 0.2 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RNA_pol_L_2 PF13656.6 KPA46851.1 - 2.9e-31 107.0 0.0 3.8e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KPA46851.1 - 1.8e-11 43.3 0.0 2.4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.25 KPA46853.1 - 2.4e-50 171.3 0.0 3.4e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46853.1 - 3e-28 98.8 0.0 3.9e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA46853.1 - 0.0021 17.4 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KPA46853.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KPA46853.1 - 0.22 11.1 0.0 0.46 10.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KPA46854.1 - 1.9e-56 191.4 0.0 9.8e-51 172.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46854.1 - 2.5e-32 112.2 0.0 4.5e-31 108.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA46854.1 - 8.8e-08 31.8 0.0 2.2e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KPA46854.1 - 0.00063 19.7 0.1 0.0013 18.7 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KPA46854.1 - 0.02 13.7 0.0 0.053 12.3 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KPA46854.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sybindin PF04099.12 KPA46855.1 - 1.6e-24 86.4 0.0 1.9e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Peroxin-3 PF04882.12 KPA46856.1 - 1.1e-171 572.0 0.1 1.3e-171 571.7 0.1 1.1 1 0 0 1 1 1 1 Peroxin-3 ATG101 PF07855.12 KPA46857.1 - 2.2e-59 199.9 0.1 2.6e-59 199.6 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Mo-co_dimer PF03404.16 KPA46857.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Forkhead PF00250.18 KPA46858.1 - 2.2e-34 117.6 0.1 4.2e-34 116.7 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain EF-hand_4 PF12763.7 KPA46859.1 - 4.3e-25 87.7 0.0 5.8e-14 51.9 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 KPA46859.1 - 0.0001 22.0 1.4 0.0049 16.7 0.2 2.7 2 0 0 2 2 2 1 WH2 motif EF-hand_7 PF13499.6 KPA46859.1 - 0.0013 19.1 0.0 0.12 12.9 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KPA46859.1 - 0.029 14.3 0.2 5.4 7.2 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain DUF812 PF05667.11 KPA46859.1 - 3.1 6.6 47.7 0.006 15.5 30.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF812) LRR_4 PF12799.7 KPA46860.1 - 0.0013 19.0 4.2 6.4 7.3 0.3 5.2 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) DUF3978 PF13123.6 KPA46860.1 - 0.04 13.7 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) LRR_6 PF13516.6 KPA46860.1 - 0.12 12.5 8.8 1.3 9.3 0.0 5.9 7 0 0 7 7 7 0 Leucine Rich repeat FAD_binding_6 PF00970.24 KPA46861.1 - 2.3e-30 104.8 0.0 3.7e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KPA46861.1 - 4.3e-28 98.1 0.0 6.5e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KPA46861.1 - 0.00051 20.2 0.0 0.033 14.3 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain TPR_2 PF07719.17 KPA46862.1 - 6.2e-30 100.9 16.5 0.00029 20.7 0.2 12.2 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 KPA46862.1 - 6.3e-30 101.8 16.8 2e-05 24.2 0.4 11.4 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 KPA46862.1 - 9.6e-22 75.3 14.3 0.0031 17.6 0.3 10.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KPA46862.1 - 3.4e-19 67.9 18.7 0.047 14.5 0.0 12.6 11 2 2 13 13 12 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPA46862.1 - 9.7e-17 61.0 17.7 2.8e-05 24.3 1.1 10.1 6 3 2 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KPA46862.1 - 1.1e-16 59.6 13.8 9.2e-05 22.2 0.0 9.6 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 KPA46862.1 - 6.8e-15 55.3 18.9 0.00069 20.1 0.0 9.9 7 3 5 12 12 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 KPA46862.1 - 5.2e-12 45.3 8.9 0.34 11.4 0.0 10.2 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 KPA46862.1 - 2e-11 43.8 15.3 1 10.2 0.1 11.5 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 KPA46862.1 - 4.3e-11 42.3 6.2 0.12 12.1 0.0 8.0 7 0 0 7 7 7 3 TPR repeat TPR_16 PF13432.6 KPA46862.1 - 4.6e-09 36.8 17.9 0.00049 20.7 0.0 7.9 9 1 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 KPA46862.1 - 1.2e-08 34.6 13.0 0.52 10.3 0.1 9.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_15 PF13429.6 KPA46862.1 - 1.7e-08 34.1 12.3 0.0016 17.7 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KPA46862.1 - 4.9e-05 23.4 1.4 3.2 8.0 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KPA46862.1 - 0.00071 19.7 17.8 0.24 11.7 0.4 7.3 8 0 0 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 FAD-SLDH PF12318.8 KPA46862.1 - 0.11 12.5 0.1 0.42 10.7 0.1 1.9 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Amnionless PF14828.6 KPA46863.1 - 0.077 11.8 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Amnionless Adeno_E3_CR2 PF02439.15 KPA46863.1 - 0.13 12.0 0.5 0.28 11.0 0.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 HemY_N PF07219.13 KPA46863.1 - 0.16 12.2 0.7 0.3 11.3 0.7 1.3 1 0 0 1 1 1 0 HemY protein N-terminus PX PF00787.24 KPA46864.1 - 2.9e-19 69.1 0.0 1e-18 67.4 0.0 2.0 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KPA46864.1 - 7.7e-12 45.3 8.0 1.8e-06 27.7 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like mRNA_cap_enzyme PF01331.19 KPA46865.1 - 3.3e-50 170.6 0.1 4.4e-50 170.2 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KPA46865.1 - 4.8e-33 114.0 0.6 8.8e-33 113.2 0.6 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KPA46865.1 - 4.3e-06 26.5 0.1 0.0014 18.4 0.1 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain HEAT PF02985.22 KPA46867.1 - 0.00052 20.0 0.0 1 9.8 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KPA46867.1 - 0.0018 18.7 1.1 0.028 14.9 0.0 3.6 3 0 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 KPA46867.1 - 0.018 15.4 4.0 0.85 10.1 0.1 5.0 6 1 0 6 6 6 0 HEAT repeats Nitr_red_assoc PF09655.10 KPA46867.1 - 3.3 8.3 5.7 26 5.4 0.0 3.5 3 0 0 3 3 3 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) SNF5 PF04855.12 KPA46868.1 - 3.2e-65 220.2 0.3 3.5e-64 216.8 0.1 2.3 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 INO80_Ies4 PF08193.11 KPA46868.1 - 0.0026 17.8 5.6 0.0026 17.8 5.6 3.1 2 1 1 3 3 3 1 INO80 complex subunit Ies4 Peptidase_M24 PF00557.24 KPA46869.1 - 1.1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.29 KPA46870.1 - 3.5e-13 49.2 19.0 1.4e-07 31.3 10.5 2.5 2 0 0 2 2 2 2 PHD-finger C1_2 PF03107.16 KPA46870.1 - 0.19 12.1 12.7 0.23 11.8 0.6 2.5 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 KPA46870.1 - 1.4 8.9 15.8 0.073 13.0 0.8 2.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KPA46870.1 - 4.7 6.9 13.7 0.11 12.0 3.8 2.8 3 0 0 3 3 3 0 PHD-finger PUF PF00806.19 KPA46871.1 - 4.5e-27 92.2 0.0 0.0001 21.8 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KPA46871.1 - 6.1e-12 45.2 0.0 1.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KPA46872.1 - 7.6e-68 228.7 1.7 7.6e-68 228.7 1.7 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46872.1 - 9.4e-53 179.1 0.1 9.4e-53 179.1 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KPA46872.1 - 7.8e-24 83.8 0.5 2.2e-23 82.3 0.0 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.6 KPA46872.1 - 2.9e-06 27.6 0.0 9.6e-06 26.0 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 KPA46872.1 - 3.5e-06 26.5 0.0 5.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KPA46872.1 - 1.1e-05 24.4 0.0 1.1e-05 24.4 0.0 2.1 2 1 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KPA46872.1 - 0.0009 18.3 0.0 0.002 17.1 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain PH PF00169.29 KPA46872.1 - 0.0025 18.3 0.1 0.006 17.1 0.1 1.7 1 0 0 1 1 1 1 PH domain Seadorna_VP7 PF07387.11 KPA46872.1 - 0.039 13.0 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KPA46872.1 - 0.1 12.5 0.2 0.1 12.5 0.2 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family HGTP_anticodon PF03129.20 KPA46873.1 - 4.6e-23 81.2 0.0 8.9e-22 77.1 0.0 2.7 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KPA46873.1 - 3e-08 33.8 0.1 2.3e-07 31.0 0.1 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase PF00069.25 KPA46874.1 - 6.9e-72 242.0 0.0 8.5e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46874.1 - 2.2e-44 151.7 0.0 2.9e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA46874.1 - 1e-06 28.3 0.0 1.9e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KPA46874.1 - 0.00098 18.5 0.1 0.0016 17.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KPA46874.1 - 0.0072 15.9 0.0 0.033 13.8 0.0 1.8 1 1 1 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.9 KPA46874.1 - 0.014 14.9 0.2 0.039 13.5 0.2 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 KPA46874.1 - 0.019 13.9 1.6 0.047 12.6 1.6 1.7 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KPA46874.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KPA46874.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KPA46874.1 - 0.17 10.6 0.6 0.24 10.1 0.5 1.3 1 1 0 1 1 1 0 Fungal protein kinase Peptidase_M76 PF09768.9 KPA46875.1 - 4.6e-65 218.6 0.6 5.6e-65 218.3 0.6 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KPA46875.1 - 0.0038 17.1 0.7 0.011 15.5 0.4 1.7 1 1 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 KPA46875.1 - 0.11 12.8 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Effector protein AA_kinase PF00696.28 KPA46876.1 - 8.2e-40 136.9 0.9 1.1e-39 136.5 0.9 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KPA46876.1 - 2.9e-19 68.8 2.2 8e-19 67.4 0.2 2.3 2 0 0 2 2 2 1 PUA domain UPF0113 PF03657.13 KPA46877.1 - 1e-25 89.8 0.0 1.9e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 KPA46877.1 - 1.7e-25 89.4 0.0 2.4e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 KPA46877.1 - 0.0071 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 PUA domain TIP41 PF04176.13 KPA46878.1 - 6.1e-68 227.7 0.1 7.5e-68 227.4 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family DEAD PF00270.29 KPA46880.1 - 5.3e-30 104.5 0.0 8.8e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPA46880.1 - 5.4e-20 71.8 0.0 9.4e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPA46880.1 - 1.1e-06 28.7 0.0 2.9e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KPA46880.1 - 0.23 10.2 0.5 1.2 7.9 0.0 2.1 1 1 1 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AMPK1_CBM PF16561.5 KPA46881.1 - 1.4e-06 28.4 0.1 2.7e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Iwr1 PF08574.10 KPA46882.1 - 2.1e-16 60.7 8.0 2.1e-16 60.7 8.0 3.0 3 1 0 3 3 3 1 Transcription factor Iwr1 SANT_DAMP1_like PF16282.5 KPA46883.1 - 0.046 13.9 0.6 0.081 13.1 0.6 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 His_Phos_1 PF00300.22 KPA46884.1 - 1.7e-18 67.0 0.0 1.9e-17 63.6 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribonuc_red_lgN PF00317.21 KPA46884.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain DUF3425 PF11905.8 KPA46885.1 - 3.7e-23 81.8 0.0 6.7e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KPA46885.1 - 1.3e-05 25.2 5.9 2.1e-05 24.5 5.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPA46885.1 - 7.3e-05 22.8 6.5 0.00013 22.0 6.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper F-box-like PF12937.7 KPA46886.1 - 7.9e-09 35.3 0.0 3.7e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 KPA46886.1 - 6e-08 32.1 18.2 0.036 14.1 0.0 8.0 9 0 0 9 9 9 2 Leucine Rich repeat F-box PF00646.33 KPA46886.1 - 5.6e-06 26.1 0.1 9.5e-05 22.2 0.0 2.9 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 KPA46886.1 - 3.6e-05 24.0 11.5 0.079 13.4 0.0 5.6 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) baeRF_family10 PF18854.1 KPA46886.1 - 1.5 9.1 4.6 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 Pkinase PF00069.25 KPA46887.1 - 3.5e-58 197.1 0.0 5e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA46887.1 - 1.5e-20 73.6 0.0 2.2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPA46887.1 - 2.6e-05 23.7 0.0 4.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KPA46887.1 - 3.3e-05 23.0 0.0 5.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KPA46887.1 - 0.0056 15.5 0.0 0.0093 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KPA46887.1 - 0.0066 16.1 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KPA46887.1 - 0.019 14.9 0.1 0.085 12.8 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family zinc_ribbon_16 PF17034.5 KPA46888.1 - 1.5e-17 63.9 8.7 3.9e-17 62.6 8.7 1.8 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KPA46888.1 - 4.9e-06 26.1 5.0 4.9e-06 26.1 5.0 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Efg1 PF10153.9 KPA46889.1 - 2.9e-34 117.8 6.9 7.6e-34 116.5 6.9 1.7 1 0 0 1 1 1 1 rRNA-processing protein Efg1 TM1586_NiRdase PF14512.6 KPA46889.1 - 0.3 10.6 1.0 0.53 9.8 1.0 1.3 1 0 0 1 1 1 0 Putative TM nitroreductase dsrm PF00035.26 KPA46890.1 - 0.00012 22.7 0.0 0.00068 20.3 0.0 2.3 2 0 0 2 2 2 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KPA46890.1 - 0.024 14.9 0.6 9.1 6.6 0.0 3.4 2 2 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 PTS_2-RNA PF01885.16 KPA46891.1 - 9.5e-62 208.3 0.0 1.1e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Gon7 PF08738.10 KPA46891.1 - 0.022 14.9 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 Gon7 family DSPc PF00782.20 KPA46893.1 - 3.2e-25 88.5 0.0 1.6e-23 83.0 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KPA46893.1 - 0.041 13.5 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase UAA PF08449.11 KPA46894.1 - 8.1e-45 153.3 8.7 1.3e-44 152.6 8.7 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KPA46894.1 - 6.5e-08 32.8 30.7 4.3e-07 30.2 5.2 3.6 4 0 0 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KPA46894.1 - 8.6e-06 25.1 1.2 0.024 13.8 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 KPA46894.1 - 0.0068 15.8 9.4 0.11 11.8 1.2 2.6 2 0 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 KPA46894.1 - 0.0075 15.3 7.3 0.12 11.3 0.5 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like DUF2892 PF11127.8 KPA46894.1 - 0.17 11.9 0.2 0.17 11.9 0.2 4.6 5 1 1 6 6 6 0 Protein of unknown function (DUF2892) KH_1 PF00013.29 KPA46895.1 - 2.2e-40 136.3 11.3 7.6e-16 57.7 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KPA46895.1 - 9.1e-10 38.2 10.6 0.013 15.3 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KPA46895.1 - 1.7e-08 34.2 4.3 0.033 14.1 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KPA46895.1 - 5.6e-05 23.1 5.9 0.23 11.5 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain Aconitase_B_N PF11791.8 KPA46897.1 - 0.19 11.8 0.9 1.2 9.2 0.1 2.4 3 0 0 3 3 3 0 Aconitate B N-terminal domain DUF664 PF04978.12 KPA46897.1 - 0.33 11.3 3.2 0.23 11.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF664) RabGAP-TBC PF00566.18 KPA46898.1 - 1.9e-17 63.6 4.9 8.3e-17 61.6 4.9 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Amidoligase_2 PF12224.8 KPA46899.1 - 8e-17 61.7 0.0 6.8e-12 45.6 0.0 4.1 3 1 0 3 3 3 2 Putative amidoligase enzyme DUF4925 PF16272.5 KPA46899.1 - 0.06 12.8 0.0 0.091 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4925) HEAT_2 PF13646.6 KPA46900.1 - 0.0084 16.5 0.0 0.066 13.6 0.0 2.4 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KPA46900.1 - 0.11 12.8 0.0 0.4 11.1 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat Nop14 PF04147.12 KPA46901.1 - 9.1e-300 996.9 30.1 1.1e-299 996.6 30.1 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4187 PF13821.6 KPA46902.1 - 1.6e-22 79.0 2.0 4.5e-22 77.6 2.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KPA46902.1 - 1.6e-09 37.5 4.2 3.9e-09 36.3 4.2 1.7 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KPA46902.1 - 0.092 12.9 1.1 0.48 10.5 1.1 2.3 1 0 0 1 1 1 0 G-patch domain HNH PF01844.23 KPA46904.1 - 0.0033 17.5 0.3 0.0089 16.2 0.3 1.8 1 1 0 1 1 1 1 HNH endonuclease DUF3545 PF12065.8 KPA46904.1 - 0.036 14.1 0.2 0.99 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) Cas3_C PF18395.1 KPA46904.1 - 0.089 13.3 0.7 0.33 11.4 0.1 2.1 2 0 0 2 2 2 0 Cas3 C-terminal domain FHA PF00498.26 KPA46906.1 - 9.3e-14 51.5 0.0 1.6e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF5427 PF10310.9 KPA46906.1 - 7.2 5.5 12.4 10 5.0 11.8 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5427) DUF676 PF05057.14 KPA46907.1 - 1.4e-05 24.8 0.0 3.4e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KPA46907.1 - 0.0001 23.0 1.0 0.00017 22.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA46907.1 - 0.027 13.7 0.1 0.055 12.7 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ADH_N PF08240.12 KPA46909.1 - 1.8e-30 105.0 0.7 3.1e-30 104.2 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPA46909.1 - 2.5e-13 50.1 0.0 3.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPA46909.1 - 1.1e-06 28.4 0.2 3.3e-06 26.8 0.2 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KPA46909.1 - 0.061 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KPA46909.1 - 0.071 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Sec7 PF01369.20 KPA46910.1 - 5.1e-29 101.2 0.1 1.7e-28 99.6 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 KPA46910.1 - 3.8e-19 69.2 0.0 8.2e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1524 PF07510.11 KPA46911.1 - 3.8e-08 33.3 0.1 4.7e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Ank_2 PF12796.7 KPA46912.1 - 0.0023 18.5 0.0 0.13 12.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPA46912.1 - 0.0037 17.5 0.6 2.5 8.5 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) DUF3618 PF12277.8 KPA46912.1 - 0.068 13.4 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) Ank_3 PF13606.6 KPA46912.1 - 0.081 13.5 3.4 15 6.6 0.0 4.5 5 0 0 5 5 5 0 Ankyrin repeat Erythro_esteras PF05139.14 KPA46913.1 - 1.7e-124 416.2 1.7 1.9e-124 416.0 1.7 1.0 1 0 0 1 1 1 1 Erythromycin esterase DIM1 PF02966.16 KPA46914.1 - 8.8e-69 229.4 0.1 9.9e-69 229.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KPA46914.1 - 0.0011 18.9 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF917 PF06032.12 KPA46915.1 - 5.8e-124 413.5 0.2 5.8e-124 413.5 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KPA46915.1 - 1.4e-30 106.3 2.0 5.9e-29 101.0 0.1 3.6 4 0 0 4 4 4 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KPA46915.1 - 1.5e-29 103.2 3.3 5.3e-25 88.3 0.1 3.4 2 1 0 3 3 3 2 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 KPA46915.1 - 2.7e-05 23.8 2.0 0.062 12.8 0.1 3.6 4 1 0 4 4 4 2 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 KPA46915.1 - 0.0018 17.0 0.6 0.41 9.2 0.0 2.9 3 0 0 3 3 3 2 MutL protein StbA PF06406.11 KPA46915.1 - 0.0056 15.9 1.0 1.9 7.6 0.1 2.7 3 0 0 3 3 3 2 StbA protein ROK PF00480.20 KPA46915.1 - 0.017 14.6 0.1 0.12 11.8 0.0 2.5 3 0 0 3 3 3 0 ROK family MreB_Mbl PF06723.13 KPA46915.1 - 0.022 13.6 3.2 0.58 8.9 0.0 3.1 2 1 1 3 3 3 0 MreB/Mbl protein HK97-gp10_like PF04883.12 KPA46915.1 - 0.15 13.1 4.2 1.9 9.5 0.4 2.9 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component CBFD_NFYB_HMF PF00808.23 KPA46915.1 - 0.18 12.1 2.4 5.1 7.5 0.9 2.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SMI1_KNR4 PF09346.10 KPA46916.1 - 8.8e-31 107.0 0.0 1.7e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Sec8_exocyst PF04048.14 KPA46917.1 - 5.2e-48 162.5 2.1 5.2e-48 162.5 2.1 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KPA46917.1 - 4.7e-11 42.5 1.9 8.1e-11 41.7 1.9 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Swi5 PF07061.11 KPA46917.1 - 0.018 15.1 0.4 0.061 13.4 0.4 1.9 1 0 0 1 1 1 0 Swi5 Vps53_N PF04100.12 KPA46917.1 - 0.063 12.2 1.1 0.13 11.2 1.1 1.5 1 0 0 1 1 1 0 Vps53-like, N-terminal ATP-grasp_4 PF13535.6 KPA46917.1 - 0.094 12.3 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp domain TMF_TATA_bd PF12325.8 KPA46917.1 - 0.49 10.6 3.1 0.73 10.1 1.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Exonuc_VII_L PF02601.15 KPA46917.1 - 0.55 9.7 4.8 0.23 11.0 2.0 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Lebercilin PF15619.6 KPA46917.1 - 3.1 7.4 8.2 1.8 8.2 4.4 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease EHN PF06441.12 KPA46918.1 - 5.1e-25 87.9 0.8 5.1e-25 87.9 0.8 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus TaqI_C PF12950.7 KPA46918.1 - 0.028 14.5 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Abhydrolase_6 PF12697.7 KPA46918.1 - 0.033 14.8 0.1 0.079 13.6 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hid1 PF12722.7 KPA46919.1 - 7e-302 1003.5 0.0 8e-302 1003.3 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KPA46919.1 - 1e-104 351.2 0.0 1.2e-104 351.0 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF913 PF06025.12 KPA46919.1 - 0.035 13.1 1.9 0.058 12.4 1.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4611 PF15387.6 KPA46919.1 - 0.059 13.6 6.3 0.13 12.5 6.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) MazG PF03819.17 KPA46919.1 - 0.088 13.0 0.7 0.19 11.9 0.7 1.5 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain DUF3246 PF11596.8 KPA46919.1 - 0.24 10.8 3.6 0.42 10.0 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Cwf_Cwc_15 PF04889.12 KPA46919.1 - 0.25 11.0 6.9 0.53 10.0 6.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KPA46919.1 - 0.48 9.7 8.9 0.72 9.1 8.9 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KPA46919.1 - 7.7 4.7 6.9 12 4.0 6.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Pet127 PF08634.10 KPA46920.1 - 2.7e-119 397.7 2.9 4.5e-119 396.9 2.9 1.4 1 0 0 1 1 1 1 Mitochondrial protein Pet127 MalF_P2 PF14785.6 KPA46920.1 - 0.0024 17.9 0.3 0.0066 16.5 0.3 1.7 1 0 0 1 1 1 1 Maltose transport system permease protein MalF P2 domain Metallophos PF00149.28 KPA46921.1 - 2.3e-13 51.1 1.8 3.6e-13 50.5 1.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FMO-like PF00743.19 KPA46922.1 - 1.4e-50 172.2 0.2 2.9e-50 171.2 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPA46922.1 - 3.1e-18 66.1 0.0 1.3e-15 57.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPA46922.1 - 1.7e-12 47.2 0.1 3.7e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPA46922.1 - 1.1e-09 38.0 0.3 5.3e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KPA46922.1 - 3.6e-06 26.4 0.1 0.021 14.1 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KPA46922.1 - 6e-06 25.7 1.7 0.0054 16.0 0.1 3.1 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KPA46922.1 - 4.4e-05 23.6 0.1 0.00012 22.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPA46922.1 - 8.8e-05 22.2 0.6 1.2 8.6 0.0 3.5 2 1 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KPA46922.1 - 0.00055 20.0 0.1 0.72 9.9 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KPA46922.1 - 0.0081 15.5 0.3 0.29 10.4 0.1 2.3 2 0 0 2 2 2 1 ThiF family NAD_binding_9 PF13454.6 KPA46922.1 - 0.016 15.2 2.9 0.38 10.7 0.2 3.2 3 1 0 3 3 3 0 FAD-NAD(P)-binding Glu_dehyd_C PF16912.5 KPA46922.1 - 0.029 13.8 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 KPA46922.1 - 0.071 13.7 0.6 10 6.8 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 KPA46922.1 - 0.13 11.9 0.0 18 4.9 0.0 3.0 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 KPA46922.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KPA46922.1 - 0.21 10.6 1.1 1.1 8.3 0.1 2.3 2 1 0 2 2 2 0 FAD binding domain ATP-synt_ab PF00006.25 KPA46923.1 - 1.2e-108 361.7 0.0 1.9e-108 361.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KPA46923.1 - 1.5e-46 157.2 0.4 6.6e-46 155.1 0.0 2.1 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension UPF0029 PF01205.19 KPA46923.1 - 1.2e-30 105.9 0.0 2.6e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 ATP-synt_ab_N PF02874.23 KPA46923.1 - 5.1e-16 58.9 2.7 1.3e-15 57.6 2.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RWD PF05773.22 KPA46923.1 - 9.8e-05 22.6 0.0 0.00061 20.1 0.0 2.4 3 1 0 3 3 3 1 RWD domain WG_beta_rep PF14903.6 KPA46923.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 WG containing repeat ACT_7 PF13840.6 KPA46924.1 - 4.3e-23 80.9 0.6 1.7e-17 62.9 0.1 2.4 2 0 0 2 2 2 2 ACT domain Methyltransf_32 PF13679.6 KPA46925.1 - 1.9e-21 76.7 0.0 3.2e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.11 KPA46926.1 - 4.4e-26 91.3 0.9 4.6e-25 88.0 0.1 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KPA46926.1 - 1.4e-07 31.3 2.5 1.7e-07 31.1 1.0 1.9 2 0 0 2 2 2 1 SNARE domain Caskin-tail PF16632.5 KPA46926.1 - 0.022 15.2 2.0 0.21 12.0 0.1 2.9 2 1 1 3 3 3 0 C-terminal region of Caskin HMMR_N PF15905.5 KPA46926.1 - 0.03 13.8 3.0 0.59 9.6 0.0 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 KPA46926.1 - 0.039 14.0 3.4 0.2 11.6 0.7 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 KPA46926.1 - 0.047 14.0 3.2 0.099 13.0 0.7 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Use1 PF09753.9 KPA46926.1 - 0.064 13.0 0.6 0.094 12.4 0.6 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 TBCA PF02970.16 KPA46926.1 - 0.066 13.5 6.3 0.11 12.9 3.0 2.7 1 1 2 3 3 3 0 Tubulin binding cofactor A DUF5089 PF17002.5 KPA46926.1 - 0.07 13.0 0.6 0.09 12.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) ArAE_2_N PF10337.9 KPA46926.1 - 0.18 10.8 0.2 0.23 10.5 0.2 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal COG2 PF06148.11 KPA46926.1 - 0.19 11.8 2.5 2.7 8.1 0.0 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc24 PF08286.11 KPA46926.1 - 0.2 11.9 3.8 0.83 9.9 0.1 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.7 KPA46926.1 - 0.29 11.3 4.1 0.25 11.5 0.6 2.1 2 1 0 2 2 2 0 Tropomyosin like NPV_P10 PF05531.12 KPA46926.1 - 0.4 11.2 3.5 2.9 8.4 0.3 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 KPA46926.1 - 0.47 10.5 6.3 2.4 8.2 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus GLE1 PF07817.13 KPA46927.1 - 9.8e-62 208.4 0.0 1.3e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 GLE1-like protein PE PF00934.20 KPA46927.1 - 2.1 8.8 0.0 2.1 8.8 0.0 3.8 4 1 1 5 5 5 0 PE family RNB PF00773.19 KPA46928.1 - 5.5e-77 259.3 0.0 9.6e-77 258.5 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KPA46928.1 - 1.3e-25 89.3 0.0 3.2e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KPA46928.1 - 1.2e-24 86.4 0.0 1.2e-24 86.4 0.0 2.3 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KPA46928.1 - 3.6e-06 27.0 0.0 0.024 14.8 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain DUF4355 PF14265.6 KPA46928.1 - 0.015 15.5 0.8 0.015 15.5 0.8 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4355) Rrp44_CSD1 PF17216.3 KPA46928.1 - 0.058 13.1 0.1 0.058 13.1 0.1 1.7 2 0 0 2 2 2 0 Rrp44-like cold shock domain Ferritin_2 PF13668.6 KPA46929.1 - 5.7e-37 127.0 0.7 8.4e-37 126.4 0.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain MKT1_C PF12246.8 KPA46930.1 - 2.8e-65 219.9 0.0 3.8e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KPA46930.1 - 5.8e-34 116.3 0.0 1.2e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KPA46930.1 - 0.00022 21.6 0.0 0.00057 20.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain DIOX_N PF14226.6 KPA46931.1 - 2e-18 67.3 0.0 3.8e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPA46931.1 - 9.1e-15 55.0 0.0 1.8e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 KPA46931.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family DNA_ligase_A_M PF01068.21 KPA46932.1 - 4.1e-21 75.6 0.0 8.3e-21 74.6 0.0 1.5 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KPA46932.1 - 3.1e-17 63.5 0.0 8.8e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus RNA_ligase PF09414.10 KPA46932.1 - 4.5e-06 27.1 0.0 8.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DUF4048 PF13257.6 KPA46934.1 - 5.4e-12 46.1 28.1 2.8e-10 40.5 22.3 3.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4048) DUF4188 PF13826.6 KPA46935.1 - 5.7e-35 120.2 0.4 8.1e-35 119.7 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 KPA46935.1 - 3.5e-05 23.4 0.1 4.8e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase Glyco_hydro_76 PF03663.14 KPA46936.1 - 1.3e-152 508.5 15.1 1.6e-152 508.3 15.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KPA46936.1 - 0.0025 16.9 14.8 0.019 14.0 0.4 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 RhlB PF12300.8 KPA46936.1 - 0.1 12.8 1.4 0.22 11.7 1.4 1.5 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Dak1 PF02733.17 KPA46937.1 - 1.5e-107 359.1 4.1 2.4e-107 358.5 4.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KPA46937.1 - 4.6e-48 163.4 0.2 1.1e-47 162.1 0.2 1.7 1 0 0 1 1 1 1 DAK2 domain DUF5635 PF18685.1 KPA46937.1 - 0.11 12.5 0.3 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5635) Nuc_deoxyrib_tr PF05014.15 KPA46937.1 - 0.17 11.9 0.3 0.64 10.0 0.2 1.9 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase LSM PF01423.22 KPA46938.1 - 9.2e-18 63.7 0.1 1.2e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KPA46938.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Hfq protein ECH_2 PF16113.5 KPA46939.1 - 2.1e-124 415.4 0.0 2.5e-124 415.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KPA46939.1 - 2e-25 89.6 0.3 7.5e-23 81.1 0.0 2.5 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase GATA PF00320.27 KPA46940.1 - 2.2e-05 23.9 4.2 0.018 14.6 0.9 2.6 2 0 0 2 2 2 2 GATA zinc finger Pol_alpha_B_N PF08418.10 KPA46941.1 - 6.4e-84 281.8 0.0 8.3e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KPA46941.1 - 2.2e-41 141.5 0.0 3.6e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MFAP1 PF06991.11 KPA46942.1 - 3.9e-65 219.7 31.5 3.9e-65 219.7 31.5 3.0 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing NOD2_WH PF17779.1 KPA46942.1 - 0.13 12.7 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 NOD2 winged helix domain Ras PF00071.22 KPA46943.1 - 6.2e-40 136.4 0.0 9.3e-39 132.6 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KPA46943.1 - 1.3e-11 44.7 0.0 2.7e-11 43.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KPA46943.1 - 0.0012 18.9 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KPA46943.1 - 0.0031 17.0 0.0 0.018 14.5 0.0 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family PRK PF00485.18 KPA46943.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AMMECR1 PF01871.17 KPA46944.1 - 2.5e-46 157.3 0.0 3.1e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 DUF2070 PF09843.9 KPA46946.1 - 0.0037 15.6 0.9 0.0052 15.1 0.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) DUF202 PF02656.15 KPA46946.1 - 0.022 15.2 0.2 0.11 13.0 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) TssN PF17555.2 KPA46946.1 - 0.029 13.7 0.5 0.045 13.1 0.5 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN MFS_1 PF07690.16 KPA46947.1 - 8.2e-42 143.4 44.5 8.8e-42 143.3 42.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPA46947.1 - 7.7e-16 58.0 9.9 7.7e-16 58.0 9.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Siva PF05458.12 KPA46948.1 - 0.061 13.0 1.2 0.11 12.2 1.2 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) RACo_linker PF17650.1 KPA46948.1 - 0.09 12.6 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 RACo linker region TFIIA PF03153.13 KPA46949.1 - 0.45 10.4 11.0 0.9 9.5 11.0 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glucosamine_iso PF01182.20 KPA46950.1 - 8e-71 238.5 0.0 9.2e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SET PF00856.28 KPA46951.1 - 4.9e-09 36.8 0.0 3.6e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KPA46951.1 - 0.023 14.8 4.7 0.023 14.8 4.7 2.2 2 0 0 2 2 2 0 MYND finger TPR_14 PF13428.6 KPA46951.1 - 1.1 10.3 3.4 73 4.6 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat CH PF00307.31 KPA46952.1 - 1.1e-13 51.4 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KPA46952.1 - 0.082 12.8 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain NDUFA12 PF05071.16 KPA46953.1 - 1e-09 39.1 4.5 1e-09 39.1 4.5 2.1 2 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 MOR2-PAG1_mid PF14228.6 KPA46954.1 - 0.07 10.8 0.0 0.11 10.2 0.0 1.2 1 0 0 1 1 1 0 Cell morphogenesis central region MFS_1 PF07690.16 KPA46955.1 - 1.7e-43 148.9 48.4 6.3e-43 147.0 47.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPA46955.1 - 1.3e-13 50.3 17.5 1.9e-13 49.7 17.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPA46955.1 - 2.9e-08 33.0 11.3 2.9e-08 33.0 11.3 2.2 2 1 1 3 3 3 1 Sugar (and other) transporter DUF4064 PF13273.6 KPA46955.1 - 0.078 13.3 0.2 0.078 13.3 0.2 4.2 4 2 0 4 4 4 0 Protein of unknown function (DUF4064) PUF PF00806.19 KPA46956.1 - 2.8e-11 42.5 0.1 1.2 9.0 0.0 7.3 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat NQR2_RnfD_RnfE PF03116.15 KPA46957.1 - 0.25 10.7 0.1 0.39 10.1 0.1 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family CobU PF02283.16 KPA46957.1 - 4.2 6.9 5.1 9.1 5.8 5.1 1.6 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Oxysterol_BP PF01237.18 KPA46958.1 - 1.3e-50 172.3 0.0 5.1e-40 137.5 0.0 2.2 1 1 1 2 2 2 2 Oxysterol-binding protein MAM33 PF02330.16 KPA46959.1 - 3.3e-73 246.2 4.7 4.8e-73 245.6 4.7 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tma16 PF11176.8 KPA46960.1 - 7.2e-47 158.9 0.2 8.8e-47 158.6 0.2 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 XPG_N PF00752.17 KPA46961.1 - 1.7e-22 79.8 0.0 4.5e-22 78.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KPA46961.1 - 4.6e-22 78.2 0.0 1.1e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KPA46961.1 - 0.0077 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing DUF5343 PF17278.2 KPA46961.1 - 0.041 14.0 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5343) 5_3_exonuc PF01367.20 KPA46961.1 - 0.12 13.0 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Pilin_GH PF16734.5 KPA46961.1 - 0.15 12.4 0.1 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Type IV pilin-like G and H, putative HHH_5 PF14520.6 KPA46961.1 - 0.18 12.4 0.5 4.2 8.0 0.0 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix domain IBR PF01485.21 KPA46962.1 - 9e-24 83.5 44.3 6e-13 48.8 5.0 4.5 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KPA46962.1 - 0.001 18.9 5.6 0.001 18.9 5.6 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.8 KPA46962.1 - 0.0018 18.7 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_2 PF13639.6 KPA46962.1 - 0.0045 17.3 7.3 0.0045 17.3 7.3 4.3 2 1 1 3 3 3 1 Ring finger domain zf-RING_4 PF14570.6 KPA46962.1 - 3.2 7.6 40.6 1.5 8.7 9.9 4.1 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain VRR_NUC PF08774.11 KPA46964.1 - 1.4e-21 76.5 0.0 3.3e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain Arc_PepC PF06819.11 KPA46964.1 - 0.068 13.3 0.1 6.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain Dpy-30 PF05186.13 KPA46965.1 - 1.2e-14 53.7 0.0 1.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.12 KPA46966.1 - 3.2e-28 97.5 0.3 7.4e-28 96.4 0.3 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain RRM_1 PF00076.22 KPA46966.1 - 1.1e-25 89.2 0.0 2.6e-11 43.1 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S15 PF00312.22 KPA46966.1 - 3.4e-14 52.8 0.1 9.2e-14 51.4 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein S15 OGG_N PF07934.12 KPA46967.1 - 9.6e-24 83.8 0.0 2.1e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KPA46967.1 - 1.8e-15 57.3 0.0 3.8e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KPA46967.1 - 0.0017 18.1 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif SF3b1 PF08920.10 KPA46968.1 - 1.7e-27 96.3 5.9 1.7e-27 96.3 5.9 2.7 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 KPA46968.1 - 1.9e-12 47.4 4.2 0.012 16.1 0.0 8.1 8 1 1 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 KPA46968.1 - 3e-11 43.5 7.8 0.35 11.3 0.0 7.6 5 3 3 9 9 9 3 HEAT repeats HEAT PF02985.22 KPA46968.1 - 3.9e-09 36.0 9.2 0.75 10.2 0.0 9.0 10 0 0 10 10 10 3 HEAT repeat Cnd1 PF12717.7 KPA46968.1 - 8.7e-07 29.1 0.7 2.3 8.2 0.0 6.2 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KPA46968.1 - 3.4e-05 24.3 0.2 1.4 9.6 0.0 5.4 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KPA46968.1 - 7.3e-05 21.5 0.3 0.028 13.0 0.0 3.2 2 2 1 3 3 3 2 Adaptin N terminal region DUF3385 PF11865.8 KPA46968.1 - 0.00032 20.6 0.3 0.055 13.4 0.0 4.4 5 1 0 6 6 6 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 KPA46968.1 - 0.00071 19.3 0.5 0.88 9.2 0.0 4.2 4 2 1 5 5 5 1 NUC173 domain UNC45-central PF11701.8 KPA46968.1 - 0.0033 17.4 0.0 0.01 15.8 0.0 1.8 2 0 0 2 2 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KPA46968.1 - 0.015 14.9 0.2 1.8 8.1 0.0 3.6 4 0 0 4 4 4 0 CLASP N terminal DRIM PF07539.12 KPA46968.1 - 0.033 12.5 0.1 16 3.7 0.0 3.7 2 1 1 3 3 3 0 Down-regulated in metastasis MMS19_C PF12460.8 KPA46968.1 - 0.17 11.0 0.0 9.7 5.2 0.0 3.3 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal zf-C2H2 PF00096.26 KPA46969.1 - 5.1e-10 39.2 11.5 2.2e-05 24.7 4.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPA46969.1 - 6.1e-09 35.9 14.2 4.7e-05 23.6 0.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPA46969.1 - 6e-07 29.8 10.8 0.0013 19.4 3.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KPA46969.1 - 7e-06 26.3 1.3 1.8e-05 25.0 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KPA46969.1 - 0.00012 22.0 2.4 0.00012 22.0 2.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPA46969.1 - 0.00057 20.1 4.2 0.00074 19.7 1.8 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KPA46969.1 - 0.044 14.1 2.4 0.062 13.6 1.4 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KPA46969.1 - 0.1 12.4 7.4 2.1 8.2 0.6 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KPA46969.1 - 0.54 10.2 4.8 12 5.9 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Rax2 PF12768.7 KPA46970.1 - 4.4e-75 251.8 0.0 6.1e-73 244.8 0.0 3.8 3 1 2 5 5 5 1 Cortical protein marker for cell polarity Kelch_4 PF13418.6 KPA46970.1 - 0.04 13.9 1.8 0.63 10.1 0.2 3.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.25 KPA46970.1 - 0.18 11.4 1.9 1.1 8.9 0.1 3.0 2 0 0 2 2 2 0 Kelch motif DUF5122 PF17164.4 KPA46970.1 - 0.19 12.1 19.7 1.4 9.3 0.0 7.5 7 0 0 7 7 7 0 Domain of unknown function (DUF5122) beta-propeller SNase PF00565.17 KPA46971.1 - 1.6e-24 86.4 0.4 1.6e-24 86.4 0.4 1.8 2 0 0 2 2 2 1 Staphylococcal nuclease homologue P34-Arc PF04045.14 KPA46972.1 - 3.8e-104 347.6 0.3 4.6e-104 347.4 0.3 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.32 KPA46973.1 - 3.5e-51 170.1 31.3 9.1e-07 29.5 0.4 11.9 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.12 KPA46973.1 - 1.6e-18 67.0 0.2 3.6e-18 65.8 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KPA46973.1 - 3.2e-18 65.8 7.2 0.028 14.7 0.1 8.9 5 2 6 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KPA46973.1 - 2.8e-06 26.9 0.1 1.9 7.8 0.0 4.2 4 1 1 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 KPA46973.1 - 3.8e-06 26.1 0.6 0.68 8.8 0.1 5.2 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KPA46973.1 - 2.8e-05 23.0 1.2 0.26 9.9 0.0 5.1 5 1 1 6 6 6 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KPA46973.1 - 0.00085 18.2 6.6 0.2 10.4 0.1 4.4 3 1 0 5 5 5 2 Nup133 N terminal like RAB3GAP2_N PF14655.6 KPA46973.1 - 0.0032 16.8 0.2 0.73 9.0 0.0 3.3 4 0 0 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus eIF2A PF08662.11 KPA46973.1 - 0.016 15.1 0.3 0.69 9.8 0.0 3.7 5 1 0 6 6 6 0 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KPA46973.1 - 0.08 12.3 0.2 7.6 5.8 0.0 3.6 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal FAA_hydrolase PF01557.18 KPA46975.1 - 6.8e-53 179.5 0.0 7.8e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.12 KPA46976.1 - 1.3e-66 222.9 0.0 1.5e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KPA46976.1 - 5.5e-06 26.0 0.0 8.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KPA46976.1 - 0.00039 20.1 0.0 0.00058 19.5 0.0 1.2 1 0 0 1 1 1 1 Cupin DZR PF12773.7 KPA46976.1 - 0.0018 18.3 1.4 0.0034 17.4 1.4 1.5 1 0 0 1 1 1 1 Double zinc ribbon AraC_binding PF02311.19 KPA46976.1 - 0.0065 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain TF_Zn_Ribbon PF08271.12 KPA46976.1 - 0.021 14.3 0.1 2.9 7.5 0.0 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_10 PF10058.9 KPA46976.1 - 0.074 12.8 0.2 0.69 9.7 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein YhfH PF14149.6 KPA46976.1 - 0.11 12.5 1.2 2.8 8.0 0.1 2.4 2 0 0 2 2 2 0 YhfH-like protein E3_UbLigase_EDD PF11547.8 KPA46976.1 - 0.13 12.0 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD C1_1 PF00130.22 KPA46976.1 - 0.14 12.0 1.8 0.82 9.6 0.3 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HalOD2 PF18547.1 KPA46976.1 - 0.44 10.5 2.4 1.1 9.2 0.4 2.3 2 1 0 2 2 2 0 Halobacterial output domain 2 OrfB_Zn_ribbon PF07282.11 KPA46976.1 - 0.98 9.4 4.5 2.7 8.0 0.3 2.4 1 1 2 3 3 3 0 Putative transposase DNA-binding domain zinc_ribbon_5 PF13719.6 KPA46976.1 - 1.7 8.5 5.3 3.9 7.3 1.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain ADK_lid PF05191.14 KPA46976.1 - 2.3 8.3 4.8 24 5.0 4.8 2.4 1 1 0 1 1 1 0 Adenylate kinase, active site lid zinc_ribbon_2 PF13240.6 KPA46976.1 - 2.8 7.8 5.1 11 5.9 0.1 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Ctr PF04145.15 KPA46977.1 - 1e-18 68.4 3.9 1.5e-16 61.3 3.9 2.0 1 1 0 1 1 1 1 Ctr copper transporter family NUDIX PF00293.28 KPA46978.1 - 1.3e-09 38.2 0.2 9e-09 35.5 0.0 2.1 1 1 1 2 2 2 1 NUDIX domain EXS PF03124.14 KPA46980.1 - 2.1e-112 375.7 7.4 2.4e-112 375.5 7.4 1.0 1 0 0 1 1 1 1 EXS family F-box-like PF12937.7 KPA46982.1 - 8.5e-05 22.4 0.2 0.00017 21.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPA46982.1 - 0.12 12.3 0.4 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 F-box domain EphA2_TM PF14575.6 KPA46983.1 - 0.0058 17.5 0.0 0.015 16.2 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KPA46983.1 - 0.0096 15.7 2.3 0.019 14.7 2.3 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 KPA46983.1 - 0.013 15.6 0.2 0.023 14.8 0.2 1.3 1 0 0 1 1 1 0 Podoplanin TMEM154 PF15102.6 KPA46983.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family BatD PF13584.6 KPA46983.1 - 0.11 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance MscL PF01741.18 KPA46983.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Syndecan PF01034.20 KPA46983.1 - 0.26 11.2 0.6 0.5 10.3 0.6 1.4 1 0 0 1 1 1 0 Syndecan domain Granulin PF00396.18 KPA46983.1 - 0.46 10.8 31.9 1.6 9.1 3.0 3.5 2 1 1 3 3 3 0 Granulin Lustrin_cystein PF14625.6 KPA46983.1 - 1.7 9.1 22.0 0.56 10.6 8.3 2.9 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain Haemadin PF09065.10 KPA46983.1 - 2.7 7.9 16.3 0.3 10.9 8.9 2.7 2 0 0 2 2 2 0 Haemadin DUF3328 PF11807.8 KPA46984.1 - 2.2e-32 112.7 1.4 2.5e-32 112.4 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.8 KPA46985.1 - 1.9e-88 296.9 0.2 2.4e-88 296.5 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA46985.1 - 2.9e-08 33.7 5.9 5e-08 32.9 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PH PF00169.29 KPA46986.1 - 2.5e-06 27.9 0.2 1.5e-05 25.4 0.0 2.3 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.17 KPA46986.1 - 4e-06 26.8 0.0 8.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KPA46986.1 - 0.0056 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KPA46986.1 - 0.017 15.3 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Spt20 PF12090.8 KPA46986.1 - 0.25 10.9 14.6 0.51 9.9 14.6 1.4 1 0 0 1 1 1 0 Spt20 family Vma12 PF11712.8 KPA46986.1 - 0.57 10.2 1.8 1.3 9.0 1.8 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Sod_Fe_C PF02777.18 KPA46987.1 - 5.3e-13 49.0 0.0 3.5e-11 43.2 0.0 2.4 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KPA46987.1 - 0.0041 17.6 0.1 0.007 16.8 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain STIMATE PF12400.8 KPA46988.1 - 4.8e-41 140.2 5.1 4.8e-41 140.2 5.1 1.7 2 0 0 2 2 2 1 STIMATE family Synaptobrevin PF00957.21 KPA46989.1 - 0.078 12.8 0.3 0.12 12.1 0.3 1.2 1 0 0 1 1 1 0 Synaptobrevin GP41 PF00517.17 KPA46989.1 - 0.17 11.7 0.1 0.24 11.3 0.1 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Corona_S2 PF01601.16 KPA46989.1 - 1.5 7.2 16.7 2 6.8 16.7 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein RCR PF12273.8 KPA46990.1 - 9.9e-19 68.1 21.2 8.4e-18 65.2 21.2 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Hum_adeno_E3A PF05393.11 KPA46990.1 - 0.033 14.2 0.3 0.046 13.7 0.3 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein SfLAP PF11139.8 KPA46990.1 - 0.038 13.4 0.1 0.05 13.0 0.1 1.1 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein GRP PF07172.11 KPA46990.1 - 1.7 9.4 19.0 0.12 13.1 6.1 2.4 1 1 1 2 2 2 0 Glycine rich protein family CPSase_L_D2 PF02786.17 KPA46992.1 - 2.3e-81 272.3 0.3 3.8e-81 271.6 0.3 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KPA46992.1 - 2.5e-69 233.0 0.0 4.6e-69 232.1 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KPA46992.1 - 2.8e-39 134.0 0.1 5.8e-39 133.0 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KPA46992.1 - 3.9e-31 107.3 0.0 1.3e-30 105.7 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KPA46992.1 - 2.8e-26 92.6 0.0 6.4e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KPA46992.1 - 3.5e-19 68.4 0.4 1e-18 66.9 0.4 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KPA46992.1 - 1.5e-12 47.1 0.4 1.1e-06 28.3 0.0 2.9 2 1 1 3 3 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KPA46992.1 - 1.6e-09 37.6 0.0 3.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KPA46992.1 - 1.1e-07 31.6 0.1 2.2e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KPA46992.1 - 1.3e-05 25.3 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KPA46992.1 - 7.3e-05 22.1 0.1 0.079 12.2 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 KPA46992.1 - 0.00013 21.7 0.0 0.0004 20.0 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.19 KPA46992.1 - 0.0036 17.1 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.6 KPA46992.1 - 0.0082 16.1 0.7 0.024 14.6 0.2 2.1 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain DUF3572 PF12096.8 KPA46992.1 - 0.0084 16.3 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3572) ATP-grasp_4 PF13535.6 KPA46992.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain HlyD_3 PF13437.6 KPA46992.1 - 0.026 15.2 0.0 0.65 10.7 0.0 3.1 2 1 1 3 3 3 0 HlyD family secretion protein ATPgrasp_ST PF14397.6 KPA46992.1 - 0.029 13.6 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 KPA46992.1 - 0.052 13.5 0.1 0.18 11.7 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) MPC PF03650.13 KPA46993.1 - 6.1e-36 122.9 0.0 7.7e-36 122.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers R3H PF01424.22 KPA46994.1 - 2e-08 34.1 0.0 4.3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KPA46994.1 - 1.4e-06 28.2 31.2 6.6e-05 22.9 11.5 7.2 7 0 0 7 7 7 3 NF-X1 type zinc finger Hydrolase_4 PF12146.8 KPA46995.1 - 6.2e-17 61.7 0.0 5.5e-12 45.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPA46995.1 - 6.8e-12 45.6 0.2 2.1e-07 30.9 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 KPA46995.1 - 2.4e-05 24.1 0.0 8e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) AXE1 PF05448.12 KPA46995.1 - 7.8e-05 21.5 0.0 2.4 6.7 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) DUF818 PF05677.12 KPA46995.1 - 0.00039 19.5 0.1 0.0013 17.8 0.1 1.7 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_6 PF12697.7 KPA46995.1 - 0.00084 20.0 0.0 0.0021 18.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KPA46995.1 - 0.0023 17.5 0.0 0.033 13.7 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KPA46995.1 - 0.0035 16.8 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 KPA46995.1 - 0.023 14.6 0.0 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KPA46995.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KPA46995.1 - 0.13 12.1 0.0 3.9 7.2 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KPA46995.1 - 0.15 11.6 0.0 0.77 9.3 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1057 PF06342.12 KPA46995.1 - 0.21 10.6 0.1 0.3 10.1 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) zf-LYAR PF08790.11 KPA46996.1 - 8.2e-14 51.2 5.9 9.5e-14 51.0 2.3 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger SASRP1 PF15160.6 KPA46996.1 - 0.0029 17.3 6.1 0.0062 16.2 6.1 1.5 1 0 0 1 1 1 1 Spermatogenesis-associated serine-rich protein 1 SCAI PF12070.8 KPA46996.1 - 2.3 7.0 7.9 0.26 10.1 1.4 2.0 2 0 0 2 2 2 0 Protein SCAI Pex2_Pex12 PF04757.14 KPA46997.1 - 1.1e-40 139.6 1.5 1.3e-40 139.3 1.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 KPA46997.1 - 1.5e-11 44.4 9.4 2.3e-11 43.9 9.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPA46997.1 - 1.7e-11 43.7 9.1 2.6e-11 43.1 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPA46997.1 - 1.7e-10 40.6 6.8 2.5e-10 40.0 6.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPA46997.1 - 5.6e-10 38.9 7.2 8.6e-10 38.3 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPA46997.1 - 3.4e-08 33.4 7.0 6.7e-08 32.4 7.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KPA46997.1 - 1.8e-07 30.9 6.4 2.7e-07 30.3 6.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KPA46997.1 - 4.1e-07 30.2 6.6 7.5e-07 29.3 6.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KPA46997.1 - 6.8e-07 29.2 6.1 1.1e-06 28.5 6.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KPA46997.1 - 1.3e-05 25.3 8.2 2e-05 24.6 8.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KPA46997.1 - 0.00062 19.8 5.2 0.0011 19.1 5.2 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KPA46997.1 - 0.0028 17.5 1.9 0.0061 16.4 1.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 KPA46997.1 - 0.0057 16.4 1.7 0.0097 15.7 1.7 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KPA46997.1 - 0.025 14.4 7.0 0.056 13.2 7.0 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KPA46997.1 - 0.039 14.0 1.7 0.062 13.4 1.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KPA46997.1 - 0.059 13.1 3.9 0.13 12.0 3.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger Fungal_trans PF04082.18 KPA46998.1 - 1e-28 100.1 0.2 1.8e-28 99.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPA46998.1 - 2.5e-10 40.3 12.9 3.9e-10 39.7 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 KPA46999.1 - 1.1e-86 291.8 0.0 1.3e-86 291.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPA46999.1 - 0.00082 19.3 0.1 0.0027 17.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPA46999.1 - 0.077 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family ETRAMP PF09716.10 KPA46999.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Abhydrolase_6 PF12697.7 KPA46999.1 - 0.64 10.6 3.0 3.1 8.3 2.9 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Mon1 PF03164.14 KPA47002.1 - 1.7e-155 518.1 0.0 2e-155 517.9 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.14 KPA47003.1 - 6.3e-115 383.5 0.0 1.4e-114 382.3 0.0 1.6 1 0 0 1 1 1 1 Dopey, N-terminal DUF3867 PF12983.7 KPA47003.1 - 0.17 11.9 0.0 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) bZIP_1 PF00170.21 KPA47004.1 - 0.0099 16.0 4.5 0.02 15.0 4.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor RRN3 PF05327.11 KPA47005.1 - 4.5e-174 580.1 0.0 4.5e-174 580.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Ferritin-like PF12902.7 KPA47005.1 - 0.015 15.2 0.0 0.05 13.5 0.0 1.8 2 0 0 2 2 2 0 Ferritin-like CBFD_NFYB_HMF PF00808.23 KPA47006.1 - 1e-29 102.6 1.1 1.5e-29 102.1 1.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KPA47006.1 - 7.4e-07 29.6 0.0 1.3e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KPA47006.1 - 0.00087 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KPA47006.1 - 0.0014 18.6 0.1 0.0025 17.8 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KPA47006.1 - 0.0018 18.4 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KPA47006.1 - 0.041 14.4 0.2 0.077 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.20 KPA47007.1 - 5.7e-26 90.5 9.5 6.5e-26 90.4 9.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4757 PF15949.5 KPA47007.1 - 0.0021 18.6 1.1 0.0027 18.2 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4757) PhaP_Bmeg PF09602.10 KPA47007.1 - 0.0041 17.1 2.4 0.067 13.1 0.2 2.1 1 1 1 2 2 2 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) SAS-6_N PF16531.5 KPA47007.1 - 0.029 15.0 0.2 0.038 14.6 0.2 1.5 1 1 0 1 1 1 0 Centriolar protein SAS N-terminal Prefoldin PF02996.17 KPA47007.1 - 0.043 13.7 5.5 0.4 10.6 0.5 2.2 1 1 1 2 2 2 0 Prefoldin subunit Tho2 PF11262.8 KPA47007.1 - 0.048 12.8 2.5 0.83 8.8 2.7 1.9 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CagS PF16707.5 KPA47007.1 - 0.055 13.5 0.5 0.07 13.1 0.5 1.1 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori DUF2089 PF09862.9 KPA47007.1 - 0.075 13.1 2.9 0.2 11.7 0.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2089) SLATT_1 PF18181.1 KPA47007.1 - 0.15 12.0 1.5 0.31 11.0 0.2 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4351 PF14261.6 KPA47007.1 - 0.24 11.5 0.3 0.24 11.5 0.3 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) Cmc1 PF08583.10 KPA47008.1 - 2.3e-15 56.3 6.9 2.9e-15 56.1 6.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 KPA47008.1 - 0.72 10.3 5.0 1.6 9.2 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Tmemb_14 PF03647.13 KPA47009.1 - 1.2e-24 86.8 6.2 1.4e-24 86.6 6.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 KPA47009.1 - 0.11 12.8 2.0 0.66 10.3 2.0 2.2 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 DAD PF02109.16 KPA47010.1 - 1.5e-38 131.5 2.4 1.8e-38 131.2 2.4 1.1 1 0 0 1 1 1 1 DAD family GRASP55_65 PF04495.14 KPA47011.1 - 5.1e-43 146.7 0.0 1.1e-41 142.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KPA47011.1 - 0.00048 19.9 0.0 0.097 12.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Methyltransf_15 PF09445.10 KPA47012.1 - 1.8e-43 147.9 0.0 2.5e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KPA47012.1 - 0.0071 16.1 0.0 0.008 15.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_5 PF01795.19 KPA47012.1 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family Cons_hypoth95 PF03602.15 KPA47012.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Wza_C PF18412.1 KPA47012.1 - 0.35 10.7 1.4 0.63 9.8 1.4 1.4 1 0 0 1 1 1 0 Outer-membrane lipoprotein Wza C-terminal domain DUF4110 PF13422.6 KPA47013.1 - 5.9e-30 103.2 0.6 5.9e-30 103.2 0.6 3.3 3 0 0 3 3 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 KPA47013.1 - 1.8e-24 85.5 18.1 1.8e-07 31.0 0.0 6.8 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KPA47013.1 - 6.2e-21 74.2 9.8 9.3e-07 29.0 0.0 5.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KPA47013.1 - 7.3e-17 61.0 1.9 3.5e-06 26.9 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KPA47013.1 - 1.3e-14 53.8 1.8 0.00027 21.1 0.1 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KPA47013.1 - 1.9e-11 43.4 5.3 0.00078 19.3 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KPA47013.1 - 2.9e-10 39.6 2.1 0.00046 19.7 0.0 5.0 4 1 0 4 4 4 2 Kelch motif BUD22 PF09073.10 KPA47013.1 - 0.81 9.0 31.9 0.065 12.6 17.3 2.4 2 0 0 2 2 2 0 BUD22 Na_trans_assoc PF06512.13 KPA47013.1 - 1.3 9.2 19.7 0.021 15.1 8.7 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated PI3K_1B_p101 PF10486.9 KPA47013.1 - 1.4 6.6 8.2 2.7 5.7 8.2 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CAC1F_C PF16885.5 KPA47013.1 - 3.1 7.4 15.0 0.13 11.9 6.3 2.3 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term CDC45 PF02724.14 KPA47013.1 - 4.2 5.5 24.3 0.025 12.9 12.6 2.1 2 0 0 2 2 2 0 CDC45-like protein Sporozoite_P67 PF05642.11 KPA47013.1 - 9.2 4.2 15.6 15 3.5 15.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_C15 PF01470.17 KPA47015.1 - 4.9e-12 46.4 0.0 0.00091 19.4 0.0 3.1 3 0 0 3 3 3 3 Pyroglutamyl peptidase DUF4279 PF14106.6 KPA47015.1 - 0.13 12.4 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) HAD_2 PF13419.6 KPA47016.1 - 8.9e-21 74.8 0.0 1.2e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPA47016.1 - 5.5e-09 36.6 0.0 0.00036 20.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPA47016.1 - 9.5e-06 26.1 0.0 1.2e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPA47016.1 - 0.00042 20.3 0.0 0.00077 19.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KPA47016.1 - 0.0038 17.3 0.0 1.8 8.7 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase GHL6 PF14871.6 KPA47016.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Homeodomain PF00046.29 KPA47017.1 - 7.9e-15 54.5 3.1 1.7e-14 53.4 3.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KPA47017.1 - 0.0049 16.7 0.8 0.015 15.2 0.8 1.9 1 0 0 1 1 1 1 Homeobox KN domain SLD3 PF08639.10 KPA47018.1 - 7.3e-171 569.6 4.3 7.3e-171 569.6 4.3 2.0 2 1 0 2 2 2 1 DNA replication regulator SLD3 DUF4246 PF14033.6 KPA47018.1 - 0.021 14.0 0.2 0.039 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Trs65 PF12735.7 KPA47019.1 - 3.1e-123 411.2 0.0 4.4e-123 410.7 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 FF PF01846.19 KPA47020.1 - 1.2e-48 163.1 10.9 1.5e-13 50.7 0.0 7.2 6 1 0 6 6 6 6 FF domain WW PF00397.26 KPA47020.1 - 1.2e-17 63.7 17.5 1.4e-09 37.9 3.3 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KPA47020.1 - 0.0038 17.9 10.7 2.3 8.9 0.0 4.7 4 0 0 4 4 4 2 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 KPA47020.1 - 3.9 7.8 9.4 7.6 6.9 0.7 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain ABC_tran PF00005.27 KPA47021.1 - 3.6e-33 115.0 0.0 1.4e-15 58.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KPA47021.1 - 1.5e-12 47.1 4.4 3.9e-12 45.8 4.4 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KPA47021.1 - 2e-12 47.0 0.0 0.0001 21.8 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPA47021.1 - 1e-09 38.7 3.5 0.15 11.8 1.1 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KPA47021.1 - 3.3e-06 27.1 0.0 0.13 12.0 0.0 2.9 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KPA47021.1 - 1.4e-05 25.4 0.0 0.003 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.27 KPA47021.1 - 3.2e-05 23.6 2.7 3.2e-05 23.6 2.7 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA PF00004.29 KPA47021.1 - 4.7e-05 23.8 0.0 0.038 14.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPA47021.1 - 4.9e-05 23.8 0.0 0.058 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Fer4_10 PF13237.6 KPA47021.1 - 5.6e-05 23.2 8.2 0.0039 17.3 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain AAA_23 PF13476.6 KPA47021.1 - 6.9e-05 23.4 0.0 0.013 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KPA47021.1 - 0.00011 22.2 0.0 0.023 14.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KPA47021.1 - 0.00029 20.8 0.0 0.79 9.6 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase RNA_helicase PF00910.22 KPA47021.1 - 0.00033 21.0 0.0 0.21 12.0 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 KPA47021.1 - 0.00042 20.9 0.1 1.7 9.2 0.1 3.2 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.6 KPA47021.1 - 0.00047 19.8 0.1 0.62 9.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.22 KPA47021.1 - 0.00054 19.6 1.0 0.052 13.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_21 PF14697.6 KPA47021.1 - 0.00065 19.8 10.1 0.0013 18.9 10.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain NACHT PF05729.12 KPA47021.1 - 0.00074 19.5 0.5 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KPA47021.1 - 0.0017 18.1 0.6 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 KPA47021.1 - 0.0024 16.6 0.2 0.0077 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPA47021.1 - 0.0024 18.0 0.0 0.56 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KPA47021.1 - 0.0024 17.6 0.2 2.3 7.9 0.0 3.1 3 0 0 3 3 3 1 Thymidylate kinase TsaE PF02367.17 KPA47021.1 - 0.0039 17.2 0.1 0.046 13.7 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KPA47021.1 - 0.0061 16.1 0.7 0.079 12.5 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 KPA47021.1 - 0.0077 16.2 0.1 0.33 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KPA47021.1 - 0.0081 16.4 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 KPA47021.1 - 0.011 15.5 2.6 0.61 9.8 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_6 PF12837.7 KPA47021.1 - 0.013 15.6 1.7 0.013 15.6 1.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 KPA47021.1 - 0.016 15.8 7.3 0.027 15.0 0.5 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KPA47021.1 - 0.031 14.4 10.7 0.061 13.5 10.7 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.6 KPA47021.1 - 0.036 13.8 0.2 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KPA47021.1 - 0.043 13.0 0.0 2.8 7.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain VirE PF05272.11 KPA47021.1 - 0.069 12.9 0.0 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E MMR_HSR1 PF01926.23 KPA47021.1 - 0.1 12.7 0.2 19 5.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase TniB PF05621.11 KPA47021.1 - 0.13 11.7 0.0 0.98 8.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Fer4_16 PF13484.6 KPA47021.1 - 0.14 13.1 0.1 0.14 13.1 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain NTPase_1 PF03266.15 KPA47021.1 - 0.22 11.4 1.6 5.9 6.8 0.0 2.6 2 0 0 2 2 2 0 NTPase CLP1_P PF16575.5 KPA47021.1 - 0.26 11.1 0.9 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 KPA47021.1 - 0.43 10.6 1.6 13 5.8 0.0 3.1 3 1 0 3 3 2 0 AAA domain Fer4_2 PF12797.7 KPA47021.1 - 2.2 8.6 10.4 0.58 10.4 1.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.23 KPA47022.1 - 2.6e-54 184.3 0.1 4.3e-54 183.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KPA47022.1 - 2.1e-25 88.4 6.7 1.2e-17 63.6 0.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KPA47022.1 - 1.7e-19 70.0 0.0 9.7e-19 67.6 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KPA47022.1 - 7.2e-19 68.2 0.0 2.2e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 KPA47022.1 - 2.5e-05 24.6 0.9 2.5e-05 24.6 0.9 5.0 3 1 1 4 4 4 1 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 KPA47022.1 - 9.6e-05 22.4 0.0 0.00039 20.4 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDH1_2_SANT_HL1 PF18375.1 KPA47022.1 - 0.0031 18.1 0.9 0.0031 18.1 0.9 3.0 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 SLIDE PF09111.10 KPA47022.1 - 0.007 16.4 2.7 0.014 15.4 0.0 3.0 3 0 0 3 3 3 1 SLIDE AAA_22 PF13401.6 KPA47022.1 - 0.015 15.6 0.0 0.048 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF4510 PF14971.6 KPA47022.1 - 0.16 12.3 0.0 0.16 12.3 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4510) Inositol_P PF00459.25 KPA47023.1 - 2.3e-41 142.1 0.1 9.1e-41 140.2 0.1 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family AAA PF00004.29 KPA47024.1 - 1.5e-55 187.2 0.0 3.6e-43 147.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KPA47024.1 - 3.5e-28 97.8 1.5 5.8e-28 97.1 0.2 2.1 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KPA47024.1 - 4.5e-14 52.0 0.5 2.4e-09 36.8 0.0 3.3 3 1 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 KPA47024.1 - 1.5e-11 44.9 5.1 4.7e-05 23.8 0.2 4.8 3 2 0 4 4 3 2 AAA ATPase domain NACHT PF05729.12 KPA47024.1 - 8.9e-09 35.5 0.4 6.3e-06 26.2 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 KPA47024.1 - 1.2e-06 28.8 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KPA47024.1 - 2e-06 27.4 0.0 9.6e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 KPA47024.1 - 5e-06 26.6 0.1 0.023 14.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KPA47024.1 - 1.2e-05 25.9 0.1 0.054 14.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KPA47024.1 - 1.9e-05 24.7 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KPA47024.1 - 1.9e-05 24.6 0.1 0.052 13.5 0.1 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KPA47024.1 - 4.8e-05 23.6 0.1 0.27 11.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KPA47024.1 - 0.00014 22.2 1.9 0.42 10.9 0.2 3.7 2 2 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 KPA47024.1 - 0.00014 22.2 0.0 0.26 11.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 KPA47024.1 - 0.00017 20.8 0.0 0.0022 17.2 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 KPA47024.1 - 0.00029 21.4 0.0 0.13 12.8 0.0 3.1 2 0 0 2 2 2 1 ABC transporter RuvB_N PF05496.12 KPA47024.1 - 0.00031 20.5 0.0 0.014 15.1 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KPA47024.1 - 0.00075 19.8 0.1 0.29 11.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain KAP_NTPase PF07693.14 KPA47024.1 - 0.0012 18.1 0.7 0.083 12.1 0.2 2.4 1 1 1 2 2 2 1 KAP family P-loop domain IstB_IS21 PF01695.17 KPA47024.1 - 0.0016 18.2 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 KPA47024.1 - 0.0023 17.2 0.1 0.74 9.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.13 KPA47024.1 - 0.003 16.8 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain PEX-2N PF09263.10 KPA47024.1 - 0.0069 16.7 0.2 4.2 7.7 0.1 2.9 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal Mg_chelatase PF01078.21 KPA47024.1 - 0.0072 15.7 0.2 0.76 9.1 0.1 2.6 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KPA47024.1 - 0.0084 15.8 0.1 0.11 12.3 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 KPA47024.1 - 0.011 16.1 2.1 2.4 8.6 0.1 2.9 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 KPA47024.1 - 0.015 15.2 0.0 0.58 10.0 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SKI PF01202.22 KPA47024.1 - 0.015 15.4 0.1 2.4 8.3 0.1 2.7 2 0 0 2 2 2 0 Shikimate kinase AAA_30 PF13604.6 KPA47024.1 - 0.015 15.0 0.1 0.77 9.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 KPA47024.1 - 0.016 15.0 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 KPA47024.1 - 0.02 14.3 0.3 5.7 6.2 0.0 2.7 3 0 0 3 3 2 0 KaiC NTPase_1 PF03266.15 KPA47024.1 - 0.021 14.7 0.1 0.39 10.6 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 KPA47024.1 - 0.03 14.7 0.1 0.53 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPA47024.1 - 0.035 13.8 0.1 8 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KPA47024.1 - 0.036 14.0 0.0 9.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 KPA47024.1 - 0.046 13.3 2.0 1.4 8.5 0.1 3.2 2 2 1 4 4 4 0 AAA domain DUF2075 PF09848.9 KPA47024.1 - 0.058 12.6 0.0 9.2 5.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KPA47024.1 - 0.062 13.0 0.0 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain APS_kinase PF01583.20 KPA47024.1 - 0.063 13.2 0.2 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 KPA47024.1 - 0.083 12.1 0.2 12 4.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain KTI12 PF08433.10 KPA47024.1 - 0.13 11.6 0.1 0.52 9.7 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Cytidylate_kin2 PF13189.6 KPA47024.1 - 0.15 12.2 0.0 5.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family RsgA_GTPase PF03193.16 KPA47024.1 - 0.25 11.2 0.8 0.44 10.4 0.1 1.8 2 0 0 2 2 1 0 RsgA GTPase MCM PF00493.23 KPA47025.1 - 3.2e-104 346.9 0.0 4.6e-104 346.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KPA47025.1 - 2.5e-30 104.9 0.7 4.3e-30 104.1 0.7 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KPA47025.1 - 2.4e-20 72.8 1.1 5e-20 71.7 1.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KPA47025.1 - 3.8e-17 62.8 1.2 1.2e-16 61.2 1.2 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KPA47025.1 - 1.3e-07 31.2 0.0 1.2e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KPA47025.1 - 5.8e-06 26.4 0.0 2.6e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KPA47025.1 - 0.0019 18.0 0.1 0.0059 16.4 0.1 1.8 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase_C PF13335.6 KPA47025.1 - 0.0019 18.8 0.4 0.013 16.1 0.2 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 KPA47025.1 - 0.021 14.7 0.0 0.075 12.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KPA47025.1 - 0.13 12.0 0.1 0.73 9.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4192 PF13830.6 KPA47025.1 - 0.27 11.3 5.6 1.4 8.9 2.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4192) DAP3 PF10236.9 KPA47026.1 - 6.2e-87 291.7 0.0 8.1e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RRS1 PF04939.12 KPA47027.1 - 1.3e-56 191.0 4.6 1.6e-56 190.7 4.6 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.27 KPA47028.1 - 3.4e-29 101.6 0.0 5.5e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Abhydrolase_1 PF00561.20 KPA47029.1 - 1.5e-16 60.8 0.7 4.9e-15 55.9 0.7 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPA47029.1 - 5.6e-15 56.6 2.2 7.1e-15 56.2 2.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPA47029.1 - 1.9e-14 53.5 0.4 1.1e-13 51.0 0.4 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 KPA47029.1 - 0.0074 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Prenyltrans PF00432.21 KPA47030.1 - 9.8e-56 185.2 8.5 8.2e-13 47.8 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KPA47030.1 - 0.0011 18.1 0.0 0.094 11.8 0.0 2.9 2 1 1 3 3 3 1 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KPA47030.1 - 0.0058 15.8 0.2 0.16 11.0 0.0 2.7 1 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SWIRM-assoc_3 PF16498.5 KPA47030.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal MutS_V PF00488.21 KPA47032.1 - 1.9e-72 243.2 0.1 3.8e-72 242.3 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KPA47032.1 - 2.8e-34 119.0 0.5 2.8e-34 119.0 0.5 2.4 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KPA47032.1 - 2.6e-29 101.8 0.0 7.2e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KPA47032.1 - 1.8e-13 50.9 0.5 4.5e-12 46.4 0.0 3.2 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 KPA47032.1 - 0.00088 19.6 0.0 0.003 17.9 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 KPA47032.1 - 0.0054 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4911) MMS19_N PF14500.6 KPA47032.1 - 0.011 15.3 0.6 0.45 10.1 0.1 2.5 1 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II AAA_23 PF13476.6 KPA47032.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAR2 PF05282.11 KPA47032.1 - 2.1 7.7 7.6 1.3 8.4 5.7 1.6 1 1 0 1 1 1 0 AAR2 protein WW PF00397.26 KPA47033.1 - 1.5e-11 44.1 0.1 4e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 KPA47033.1 - 4.8e-05 22.6 1.1 0.00068 18.8 1.1 2.2 1 1 0 1 1 1 1 PhoD-like phosphatase PMM PF03332.13 KPA47034.1 - 6.2e-104 346.6 0.3 7.2e-104 346.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KPA47034.1 - 0.00037 20.3 0.0 0.0019 18.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPA47034.1 - 0.12 12.8 0.0 9.1 6.6 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 KPA47034.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase Na_Ca_ex PF01699.24 KPA47035.1 - 1.4e-52 177.7 41.4 1.1e-28 100.1 17.0 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein MARVEL PF01284.23 KPA47035.1 - 0.0057 16.7 0.4 0.0057 16.7 0.4 4.1 4 2 1 5 5 5 2 Membrane-associating domain Cnd2 PF05786.14 KPA47036.1 - 0 1060.1 8.0 0 1059.8 8.0 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KPA47036.1 - 0.0043 17.3 0.0 0.0043 17.3 0.0 2.1 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF3602 PF12223.8 KPA47036.1 - 0.042 14.5 0.3 0.24 12.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) HMG_box PF00505.19 KPA47037.1 - 7.5e-17 61.5 0.8 1.6e-16 60.5 0.8 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KPA47037.1 - 2.3e-15 56.9 1.2 4.9e-15 55.9 1.2 1.6 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.30 KPA47037.1 - 4.6e-10 39.8 0.0 7.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KPA47037.1 - 3.9e-07 30.1 0.0 7.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_5 PF14887.6 KPA47037.1 - 1.7 8.7 4.1 1.1 9.3 0.9 2.0 1 1 1 2 2 2 0 HMG (high mobility group) box 5 Spc7 PF08317.11 KPA47038.1 - 0.0068 15.3 1.7 0.0083 15.0 1.7 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein CLZ PF16526.5 KPA47038.1 - 0.041 14.3 0.3 0.081 13.3 0.3 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAMP PF00672.25 KPA47039.1 - 1.6e-43 146.9 14.3 9.3e-09 35.5 0.2 7.3 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.26 KPA47039.1 - 2.7e-30 105.2 1.0 8.8e-30 103.5 0.3 2.3 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPA47039.1 - 6e-25 87.6 0.2 6e-25 87.6 0.2 3.0 3 0 0 3 3 2 1 Response regulator receiver domain HisKA PF00512.25 KPA47039.1 - 1.7e-16 60.0 0.6 1.7e-16 60.0 0.6 3.7 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 KPA47039.1 - 2.7e-06 27.7 15.0 2.1 8.8 0.1 7.4 2 2 5 8 8 8 3 Syntaxin-like protein Fib_alpha PF08702.10 KPA47039.1 - 0.0022 18.2 34.0 0.61 10.3 0.2 6.5 6 0 0 6 6 6 2 Fibrinogen alpha/beta chain family DUF3829 PF12889.7 KPA47039.1 - 0.0041 16.7 11.6 1.9 7.9 0.2 4.6 4 2 1 5 5 5 3 Protein of unknown function (DUF3829) DUF948 PF06103.11 KPA47039.1 - 0.0043 17.3 46.2 0.9 9.8 2.1 9.8 2 1 4 6 6 6 3 Bacterial protein of unknown function (DUF948) DUF4795 PF16043.5 KPA47039.1 - 0.0064 16.1 24.9 0.14 11.7 4.2 5.1 1 1 3 4 4 4 1 Domain of unknown function (DUF4795) DUF4279 PF14106.6 KPA47039.1 - 0.0099 16.1 0.0 34 4.7 0.0 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF4279) CMD PF02627.20 KPA47039.1 - 0.02 14.9 3.4 18 5.4 0.0 5.4 6 0 0 6 6 6 0 Carboxymuconolactone decarboxylase family GhoS PF11080.8 KPA47039.1 - 0.11 12.5 7.5 0.59 10.1 0.1 3.8 4 0 0 4 4 4 0 Endoribonuclease GhoS GLE1 PF07817.13 KPA47039.1 - 0.28 10.3 7.3 13 4.9 0.0 4.5 3 1 2 5 5 5 0 GLE1-like protein BORCS6 PF10157.9 KPA47039.1 - 1.1 9.4 12.6 9.5 6.4 0.1 5.8 4 2 3 7 7 6 0 BLOC-1-related complex sub-unit 6 DUF883 PF05957.13 KPA47039.1 - 1.8 9.2 18.9 3.5 8.3 0.2 6.2 4 2 3 7 7 7 0 Bacterial protein of unknown function (DUF883) Flagellin_C PF00700.21 KPA47039.1 - 5.6 7.4 25.8 0.92 9.9 0.2 6.7 7 0 0 7 7 7 0 Bacterial flagellin C-terminal helical region PMC2NT PF08066.12 KPA47039.1 - 5.9 7.6 9.5 3.5 8.4 1.6 4.4 4 1 1 5 5 5 0 PMC2NT (NUC016) domain Membr_traf_MHD PF10540.9 KPA47040.1 - 3e-18 66.4 1.2 3.2e-15 56.6 1.2 3.0 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KPA47040.1 - 8.8e-17 61.3 0.0 2.1e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 KPA47040.1 - 5.5e-09 35.1 0.1 1.2e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) ArfGap PF01412.18 KPA47041.1 - 9.1e-33 112.8 0.0 3.3e-32 111.0 0.0 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KPA47041.1 - 7.6e-21 74.9 16.1 1.2e-20 74.2 16.1 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KPA47041.1 - 1.2e-11 45.0 0.6 3.1e-11 43.7 0.1 2.0 2 0 0 2 2 2 1 PH domain TF_Zn_Ribbon PF08271.12 KPA47041.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding PH_9 PF15410.6 KPA47041.1 - 1.4 9.3 4.4 3.1 8.2 0.8 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain Pkinase PF00069.25 KPA47042.1 - 4.5e-78 262.3 0.0 6.2e-78 261.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPA47042.1 - 1.1e-38 133.1 0.0 1.5e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KPA47042.1 - 8.3e-16 58.1 0.3 1.9e-15 57.0 0.3 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KPA47042.1 - 7.1e-12 45.2 0.0 5.5e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 KPA47042.1 - 5e-09 36.4 0.0 1.1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 KPA47042.1 - 9.5e-06 24.6 0.3 1.5e-05 23.9 0.3 1.6 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KPA47042.1 - 0.0047 16.3 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KPA47042.1 - 0.024 13.6 0.1 0.024 13.6 0.1 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KPA47042.1 - 0.029 13.4 0.2 0.065 12.2 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 KPA47042.1 - 0.07 12.8 0.1 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KPA47042.1 - 0.078 12.9 0.0 3.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2961 PF11175.8 KPA47042.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) PCI PF01399.27 KPA47043.1 - 2.6e-14 53.6 1.0 7e-14 52.2 0.1 2.2 3 0 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 KPA47043.1 - 4.1e-11 42.4 0.5 9.5e-11 41.2 0.5 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Vps35 PF03635.17 KPA47043.1 - 0.0046 15.5 0.3 0.051 12.1 0.0 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 35 ENT PF03735.14 KPA47043.1 - 0.023 14.7 0.1 4.3 7.5 0.0 3.1 2 0 0 2 2 2 0 ENT domain zf-GRF PF06839.12 KPA47045.1 - 2.6e-08 33.8 7.3 5.1e-08 32.9 7.3 1.5 1 0 0 1 1 1 1 GRF zinc finger Prefoldin_2 PF01920.20 KPA47045.1 - 0.0015 18.4 0.3 0.0031 17.5 0.3 1.5 1 0 0 1 1 1 1 Prefoldin subunit SPATA24 PF15175.6 KPA47045.1 - 0.064 13.2 2.0 0.21 11.5 0.3 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 Csm1_N PF18504.1 KPA47045.1 - 0.077 13.3 0.7 0.18 12.2 0.7 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF4834 PF16118.5 KPA47045.1 - 6.6 7.8 5.3 4.1 8.4 1.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) ADK PF00406.22 KPA47046.1 - 2.7e-44 150.9 0.0 3.4e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KPA47046.1 - 1.4e-36 125.9 0.0 1.9e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KPA47046.1 - 2.7e-08 34.4 0.0 4.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KPA47046.1 - 3.9e-07 30.3 0.0 6.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KPA47046.1 - 0.0053 16.4 0.1 1.7 8.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.12 KPA47046.1 - 0.091 12.0 0.0 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin PQ-loop PF04193.14 KPA47048.1 - 1.1e-18 66.8 3.2 2.1e-12 46.6 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat VGLL4 PF15245.6 KPA47049.1 - 0.0058 16.7 0.7 0.0086 16.2 0.7 1.3 1 0 0 1 1 1 1 Transcription cofactor vestigial-like protein 4 UPF0054 PF02130.17 KPA47049.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein family UPF0054 Pol_alpha_B_N PF08418.10 KPA47049.1 - 1.4 8.8 4.3 3.3 7.6 4.2 1.7 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MTHFR PF02219.17 KPA47050.1 - 7.7e-103 343.8 0.0 1.1e-102 343.2 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase tRNA-synt_1 PF00133.22 KPA47051.1 - 1.5e-53 182.0 0.3 2.3e-19 69.1 0.1 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KPA47051.1 - 3.4e-43 147.3 0.0 6e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KPA47051.1 - 1.2e-29 103.3 0.1 3e-19 69.0 0.0 5.1 4 1 1 5 5 5 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KPA47051.1 - 1.9e-13 50.7 0.0 5.3e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Zn-ribbon_8 PF09723.10 KPA47051.1 - 0.28 11.3 2.1 0.78 9.9 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 KPA47051.1 - 0.39 10.2 2.0 10 5.7 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain PQ-loop PF04193.14 KPA47052.1 - 7.3e-33 112.1 8.2 5e-16 58.2 0.6 2.6 2 0 0 2 2 2 2 PQ loop repeat # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fusarium_langsethiae-ASM129263v1/GCA_001292635.1_ASM129263v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fusarium_langsethiae-ASM129263v1/GCA_001292635.1_ASM129263v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fusarium_langsethiae-ASM129263v1/GCA_001292635.1_ASM129263v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fusarium_langsethiae-ASM129263v1/GCA_001292635.1_ASM129263v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 20:44:48 2019 # [ok]